LOCUS       DAEQJM010000001       157814 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.001, whole genome shotgun sequence.
ACCESSION   DAEQJM010000001 DAEQJM010000000
VERSION     DAEQJM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 157814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 157814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..157814
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.001"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            268..2457
                     /locus_tag="KRQ43_000001"
     CDS             268..2457
                     /locus_tag="KRQ43_000001"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HBH2740383.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEEFIDIKTDLEKVTKANISIRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            2525..3292
                     /locus_tag="KRQ43_000002"
     CDS             2525..3292
                     /locus_tag="KRQ43_000002"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBH2740384.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            3350..4366
                     /locus_tag="KRQ43_000003"
     CDS             3350..4366
                     /locus_tag="KRQ43_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH2740385.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVYAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            4432..4680
                     /locus_tag="KRQ43_000004"
     CDS             4432..4680
                     /locus_tag="KRQ43_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740386.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELGVLLEEKKELEEE"
     gene            complement(4857..5354)
                     /locus_tag="KRQ43_000005"
     CDS             complement(4857..5354)
                     /locus_tag="KRQ43_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH2740387.1"
                     /translation="MYKIGESVMYPKEGACYISGLVTKDINHHIQKYYELTVIYNSNL
                     KISIPVLNADKIGVRPIMDENEVENFIQSLDKVDCLWVFDRKKRLKLYHDKFHSGDVF
                     EIVKLIKMLMIQDNSKQLCSTDKDFLNKAQRFALSELAAAQCKSYTIVLEEMKNHILN
                     SKNNN"
     gene            complement(5595..6659)
                     /locus_tag="KRQ43_000006"
     CDS             complement(5595..6659)
                     /locus_tag="KRQ43_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2740388.1"
                     /translation="MIRLTIANIKRYIKNHALLVNMVLFPVILMFYLNFFTGNSENQS
                     MYFSPVAIVSNSSGKYEHKLIDSSKLKENSFGLNEQDKAMDLLKNNKVSAVFILDKNF
                     SSNIDNLKRPEVKCFKTENGGGSLWAESQIESFITNSLKLKIDRNIDDKLTKTNIIDN
                     SSGKNKNSFLIVFLICYFMYINAAHLASDLFSLKKSNTLKRLVSTKHNDIKIIFSIFL
                     GLFFTQAIVYTLTLVCFTSISNFKLTLNTLMIVLANSFVATGFVFWIARVFKNEGSIS
                     LMSTFYSLIGLAISISNMIPSLDKLSFMANLSKLTPFYWTIDAINNNGNILINIIVLI
                     LIGMVFVTAGSLNLRDFARN"
     gene            complement(6662..7759)
                     /locus_tag="KRQ43_000007"
     CDS             complement(6662..7759)
                     /locus_tag="KRQ43_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2740389.1"
                     /translation="MKLYISVKTMLKVLKSSFMLNLIYFLALPLVLAGFLGMVTESIF
                     QNPIKTDLTSIVIYDKDNTKLSSNLTGYLKNDLSSILTVQKDDSKADLKLTIPKGYEN
                     NLLNEKSNNLSIEKLKSNDNIAILLQDILDTYHEKLYLNNSQKLSSEDFSKLFNKNSI
                     DTSIIKNNVKQNSYEYFALVSLGFFAIIFIMNSILSNYVSESKGLSKRLYSIPVTRVQ
                     FLIYDFIGFWIYSFIFLSLYVLFFRTLGVTFKGNFVILALLCALASYFMTSISTFITT
                     FFSKKYGTVIVYALLFLQTVFGGIFSIVNDVFTKFTSLSPTYLIGTLFSNYETFKTID
                     SIESLIFTCLIASTVLIALSIVKEKYKWREV"
     gene            complement(7773..8708)
                     /locus_tag="KRQ43_000008"
     CDS             complement(7773..8708)
                     /locus_tag="KRQ43_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2740390.1"
                     /translation="MDIVRVNNITKRFNDKLALDNISFSVKEGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGDIQINGLDLSKDCIKAKSIIGLVPQELALIETLTPFDNLEYFGT
                     YYGLKGKLLQERITEALEVTGLTDVKKKKIKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKNISKKQKTTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVVSILENNSLLELGVDKKLQLTDV
                     LSVVDKNNSKITRISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(8896..9540)
                     /locus_tag="KRQ43_000009"
     CDS             complement(8896..9540)
                     /locus_tag="KRQ43_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740391.1"
                     /translation="MNKIKVLIVDDEKLIRKGLNIILSSYDDLEIVGDASNGYEALEF
                     CKTNDVDIVLMDIRMKVCDGVLGTRLIKEYDSSIALLILTTFNDDEYIEDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMYPQKTIEQKHISDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILGKLELRDRTQLVIFAFKNKIVI"
     gene            complement(9533..10693)
                     /locus_tag="KRQ43_000010"
     CDS             complement(9533..10693)
                     /locus_tag="KRQ43_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH2740392.1"
                     /translation="MNRKKTFIFIRYLSLFILLISYLNHTENTLYPAITMIILFLIIN
                     NQVRFFSLSSENKFILISYFLELILIFIFCKYIKTFNPLYYVSLILDASFLIKEKYKY
                     ILFSLVIIFSFIIGLDKNLYLALESSSTLLIITLFSVYLENENLSKLYNQSLYDKLRV
                     SKDELKKANADLEIYANSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLLK
                     DKPLISDLVHELREFVTESFQDVRRAISELKPIEYENYQNLLKIRELVNSFIKLTNIN
                     VRLTISKNTWNLSTNQSIALYRLVQESLSNASRHGKATEIRIFITFNPSNLIITISDN
                     GIGCNNIKRGNGLSSISERIYELNGKVEFDNSNTGFTIRASFPKFSGGDFFE"
     gene            10878..11222
                     /locus_tag="KRQ43_000011"
     CDS             10878..11222
                     /locus_tag="KRQ43_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBH2740393.1"
                     /translation="MNNKEKGDFGEEIAVNYLLSKGAKILEKNYRLRIGEVDIIANIG
                     DEVVFVEVKSRSNIKYGYPCESVDFKKRKKIIGVAKYYIIKNNLNNTPIRFDIIEVYL
                     LEKRINHIMNAF"
     gene            11253..12854
                     /locus_tag="KRQ43_000012"
     CDS             11253..12854
                     /locus_tag="KRQ43_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBH2740394.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLLVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVSIMSFLDDKSRKENGELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISIEEMIEVSKV
                     YSILGMINESKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            12873..13973
                     /gene="dprA"
                     /locus_tag="KRQ43_000013"
     CDS             12873..13973
                     /gene="dprA"
                     /locus_tag="KRQ43_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBH2740395.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGYAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            14006..16093
                     /gene="topA"
                     /locus_tag="KRQ43_000014"
     CDS             14006..16093
                     /gene="topA"
                     /locus_tag="KRQ43_000014"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBH2740396.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            16258..17043
                     /gene="codY"
                     /locus_tag="KRQ43_000015"
     CDS             16258..17043
                     /gene="codY"
                     /locus_tag="KRQ43_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBH2740397.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAENSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            17150..18415
                     /locus_tag="KRQ43_000016"
     CDS             17150..18415
                     /locus_tag="KRQ43_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBH2740398.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            18446..19216
                     /locus_tag="KRQ43_000017"
     CDS             18446..19216
                     /locus_tag="KRQ43_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2740399.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDTLAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            19325..19771
                     /locus_tag="KRQ43_000018"
     CDS             19325..19771
                     /locus_tag="KRQ43_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH2740400.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            19789..20982
                     /gene="nifS"
                     /locus_tag="KRQ43_000019"
     CDS             19789..20982
                     /gene="nifS"
                     /locus_tag="KRQ43_000019"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HBH2740401.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGRVDLRQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            21036..21476
                     /gene="nifU"
                     /locus_tag="KRQ43_000020"
     CDS             21036..21476
                     /gene="nifU"
                     /locus_tag="KRQ43_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HBH2740402.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            21765..22844
                     /gene="mnmA"
                     /locus_tag="KRQ43_000021"
     CDS             21765..22844
                     /gene="mnmA"
                     /locus_tag="KRQ43_000021"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBH2740403.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    22987..23225
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            23293..25932
                     /gene="alaS"
                     /locus_tag="KRQ43_000022"
     CDS             23293..25932
                     /gene="alaS"
                     /locus_tag="KRQ43_000022"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBH2740404.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            25957..26214
                     /locus_tag="KRQ43_000023"
     CDS             25957..26214
                     /locus_tag="KRQ43_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBH2740405.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            26224..28395
                     /locus_tag="KRQ43_000024"
     CDS             26224..28395
                     /locus_tag="KRQ43_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740406.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYGTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNVGYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIININMIIFEKNN"
     gene            28601..29026
                     /gene="ruvX"
                     /locus_tag="KRQ43_000025"
     CDS             28601..29026
                     /gene="ruvX"
                     /locus_tag="KRQ43_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBH2740407.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            29104..29391
                     /locus_tag="KRQ43_000026"
     CDS             29104..29391
                     /locus_tag="KRQ43_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBH2740408.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            29673..30131
                     /locus_tag="KRQ43_000027"
     CDS             29673..30131
                     /locus_tag="KRQ43_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH2740409.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(30248..30985)
                     /locus_tag="KRQ43_000028"
     CDS             complement(30248..30985)
                     /locus_tag="KRQ43_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH2740410.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            31202..32878
                     /locus_tag="KRQ43_000029"
     CDS             31202..32878
                     /locus_tag="KRQ43_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBH2740411.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            33084..33284
                     /locus_tag="KRQ43_000030"
     CDS             33084..33284
                     /locus_tag="KRQ43_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HBH2740412.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            33338..34501
                     /locus_tag="KRQ43_000031"
     CDS             33338..34501
                     /locus_tag="KRQ43_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH2740413.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(34712..35134)
                     /locus_tag="KRQ43_000032"
     CDS             complement(34712..35134)
                     /locus_tag="KRQ43_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HBH2740414.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(35155..35991)
                     /locus_tag="KRQ43_000033"
     CDS             complement(35155..35991)
                     /locus_tag="KRQ43_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH2740415.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            36289..36885
                     /locus_tag="KRQ43_000034"
     CDS             36289..36885
                     /locus_tag="KRQ43_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HBH2740416.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLIYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGIYQIILSPIYTVLLKIVYLFV"
     gene            36915..37634
                     /locus_tag="KRQ43_000035"
     CDS             36915..37634
                     /locus_tag="KRQ43_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBH2740417.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            37636..38175
                     /gene="scpB"
                     /locus_tag="KRQ43_000036"
     CDS             37636..38175
                     /gene="scpB"
                     /locus_tag="KRQ43_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBH2740418.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            38337..38966
                     /locus_tag="KRQ43_000037"
     CDS             38337..38966
                     /locus_tag="KRQ43_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HBH2740419.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADINNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTKSYGNNS"
     gene            38920..39348
                     /gene="ytfJ"
                     /locus_tag="KRQ43_000038"
     CDS             38920..39348
                     /gene="ytfJ"
                     /locus_tag="KRQ43_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HBH2740420.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            39596..40036
                     /locus_tag="KRQ43_000039"
     CDS             39596..40036
                     /locus_tag="KRQ43_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2740421.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            40052..41503
                     /locus_tag="KRQ43_000040"
     CDS             40052..41503
                     /locus_tag="KRQ43_000040"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBH2740422.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGSFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAIETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(41594..42262)
                     /locus_tag="KRQ43_000041"
     CDS             complement(41594..42262)
                     /locus_tag="KRQ43_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HBH2740423.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSQYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            42531..42671
                     /locus_tag="KRQ43_000042"
     CDS             42531..42671
                     /locus_tag="KRQ43_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740424.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(42846..43166)
                     /locus_tag="KRQ43_000043"
     CDS             complement(42846..43166)
                     /locus_tag="KRQ43_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH2740425.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(43286..44023)
                     /locus_tag="KRQ43_000044"
     CDS             complement(43286..44023)
                     /locus_tag="KRQ43_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBH2740426.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            44238..46061
                     /gene="acd"
                     /locus_tag="KRQ43_000045"
     CDS             44238..46061
                     /gene="acd"
                     /locus_tag="KRQ43_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HBH2740427.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYIS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            46276..50574
                     /locus_tag="KRQ43_000046"
     CDS             46276..50574
                     /locus_tag="KRQ43_000046"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBH2740428.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEILPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            50778..51239
                     /locus_tag="KRQ43_000047"
     CDS             50778..51239
                     /locus_tag="KRQ43_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBH2740429.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            51269..52423
                     /gene="nusA"
                     /locus_tag="KRQ43_000048"
     CDS             51269..52423
                     /gene="nusA"
                     /locus_tag="KRQ43_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBH2740430.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVKSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELGTSEDNFSEEE"
     gene            52430..52711
                     /locus_tag="KRQ43_000049"
     CDS             52430..52711
                     /locus_tag="KRQ43_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBH2740431.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            52701..53012
                     /locus_tag="KRQ43_000050"
     CDS             52701..53012
                     /locus_tag="KRQ43_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HBH2740432.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            53034..54974
                     /gene="infB"
                     /locus_tag="KRQ43_000051"
     CDS             53034..54974
                     /gene="infB"
                     /locus_tag="KRQ43_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBH2740433.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            55017..55397
                     /gene="rbfA"
                     /locus_tag="KRQ43_000052"
     CDS             55017..55397
                     /gene="rbfA"
                     /locus_tag="KRQ43_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBH2740434.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDNLIKRVNEKNAQQNEDENYDE"
     gene            55378..56361
                     /locus_tag="KRQ43_000053"
     CDS             55378..56361
                     /locus_tag="KRQ43_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBH2740435.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNVGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLRFLVEGVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQTKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSDYYKLLGEA
                     LKGLEIFDSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYVDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            56374..57279
                     /gene="truB"
                     /locus_tag="KRQ43_000054"
     CDS             56374..57279
                     /gene="truB"
                     /locus_tag="KRQ43_000054"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBH2740436.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEVVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            57410..58339
                     /locus_tag="KRQ43_000055"
     CDS             57410..58339
                     /locus_tag="KRQ43_000055"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBH2740437.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEYAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            58443..58700
                     /gene="rpsO"
                     /locus_tag="KRQ43_000056"
     CDS             58443..58700
                     /gene="rpsO"
                     /locus_tag="KRQ43_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBH2740438.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            58940..59785
                     /locus_tag="KRQ43_000057"
     CDS             58940..59785
                     /locus_tag="KRQ43_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH2740439.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            59910..62021
                     /gene="pnp"
                     /locus_tag="KRQ43_000058"
     CDS             59910..62021
                     /gene="pnp"
                     /locus_tag="KRQ43_000058"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBH2740440.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            62287..63030
                     /locus_tag="KRQ43_000059"
     CDS             62287..63030
                     /locus_tag="KRQ43_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH2740441.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            63188..64435
                     /locus_tag="KRQ43_000060"
     CDS             63188..64435
                     /locus_tag="KRQ43_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH2740442.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAICLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            64470..64715
                     /locus_tag="KRQ43_000061"
     CDS             64470..64715
                     /locus_tag="KRQ43_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH2740443.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            64725..65948
                     /gene="dapG"
                     /locus_tag="KRQ43_000062"
     CDS             64725..65948
                     /gene="dapG"
                     /locus_tag="KRQ43_000062"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH2740444.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEENIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            66061..66795
                     /locus_tag="KRQ43_000063"
     CDS             66061..66795
                     /locus_tag="KRQ43_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HBH2740445.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            66918..69329
                     /locus_tag="KRQ43_000064"
     CDS             66918..69329
                     /locus_tag="KRQ43_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBH2740446.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKSNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKSSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            69332..70390
                     /gene="mnmH"
                     /locus_tag="KRQ43_000065"
     CDS             69332..70390
                     /gene="mnmH"
                     /locus_tag="KRQ43_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBH2740447.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESVFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            70384..71718
                     /gene="rimO"
                     /locus_tag="KRQ43_000066"
     CDS             70384..71718
                     /gene="rimO"
                     /locus_tag="KRQ43_000066"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBH2740448.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFSELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            71705..72247
                     /gene="pgsA"
                     /locus_tag="KRQ43_000067"
     CDS             71705..72247
                     /gene="pgsA"
                     /locus_tag="KRQ43_000067"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBH2740449.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            72535..73581
                     /gene="recA"
                     /locus_tag="KRQ43_000068"
     CDS             72535..73581
                     /gene="recA"
                     /locus_tag="KRQ43_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBH2740450.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            73757..75298
                     /gene="rny"
                     /locus_tag="KRQ43_000069"
     CDS             73757..75298
                     /gene="rny"
                     /locus_tag="KRQ43_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBH2740451.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            75933..77714
                     /locus_tag="KRQ43_000070"
     CDS             75933..77714
                     /locus_tag="KRQ43_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBH2740452.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(77796..78326)
                     /gene="lepB"
                     /locus_tag="KRQ43_000071"
     CDS             complement(77796..78326)
                     /gene="lepB"
                     /locus_tag="KRQ43_000071"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH2740453.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSVVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEILG
                     KVMVRLLPLDNIGKVD"
     gene            complement(78366..79190)
                     /locus_tag="KRQ43_000072"
     CDS             complement(78366..79190)
                     /locus_tag="KRQ43_000072"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH2740454.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILINEFIKLNF
                     SNTFINTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRVFFNSTVVAIALIVYGIIMIGLEKRNKRPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            79447..80355
                     /locus_tag="KRQ43_000073"
     CDS             79447..80355
                     /locus_tag="KRQ43_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH2740455.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            80499..81944
                     /locus_tag="KRQ43_000074"
     CDS             80499..81944
                     /locus_tag="KRQ43_000074"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBH2740456.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINKRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            82255..82707
                     /locus_tag="KRQ43_000075"
     CDS             82255..82707
                     /locus_tag="KRQ43_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2740457.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            83120..84697
                     /locus_tag="KRQ43_000076"
     CDS             83120..84697
                     /locus_tag="KRQ43_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH2740458.1"
                     /translation="MKQKMKEFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     IPFLENNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGILAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYALVYYNVFKVLILRFNLQTPGREEITDINFDLEPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKENIEDITNCITRLRVVVKDMSKVDENAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            84856..85608
                     /locus_tag="KRQ43_000077"
     CDS             84856..85608
                     /locus_tag="KRQ43_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH2740459.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            85741..87087
                     /locus_tag="KRQ43_000078"
     CDS             85741..87087
                     /locus_tag="KRQ43_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH2740460.1"
                     /translation="MTMKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVV
                     EERQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKI
                     PLQFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALK
                     RVFPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDL
                     VPKIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKV
                     AKSNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIVEVAEAIAH
                     NKHQIAIVITENNGAINNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAY
                     EKLAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(87199..88395)
                     /locus_tag="KRQ43_000079"
     CDS             complement(87199..88395)
                     /locus_tag="KRQ43_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH2740461.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            88780..89730
                     /gene="galT"
                     /locus_tag="KRQ43_000080"
     CDS             88780..89730
                     /gene="galT"
                     /locus_tag="KRQ43_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBH2740462.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            89891..90643
                     /gene="xth"
                     /locus_tag="KRQ43_000081"
     CDS             89891..90643
                     /gene="xth"
                     /locus_tag="KRQ43_000081"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBH2740463.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(90735..91511)
                     /locus_tag="KRQ43_000082"
     CDS             complement(90735..91511)
                     /locus_tag="KRQ43_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH2740464.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGVGDLKELYRNINYHKLPSSSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            91826..93724
                     /locus_tag="KRQ43_000083"
     CDS             91826..93724
                     /locus_tag="KRQ43_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HBH2740465.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            complement(93852..94973)
                     /locus_tag="KRQ43_000084"
     CDS             complement(93852..94973)
                     /locus_tag="KRQ43_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HBH2740466.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLEEFKTVIHPEKIADYISELIDNHYS"
     gene            95172..95504
                     /locus_tag="KRQ43_000085"
     CDS             95172..95504
                     /locus_tag="KRQ43_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH2740467.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            95491..96549
                     /locus_tag="KRQ43_000086"
     CDS             95491..96549
                     /locus_tag="KRQ43_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBH2740468.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNIKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSVTIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            96542..97612
                     /locus_tag="KRQ43_000087"
     CDS             96542..97612
                     /locus_tag="KRQ43_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBH2740469.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDISVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSTSSYLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSNMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            97714..98250
                     /locus_tag="KRQ43_000088"
     CDS             97714..98250
                     /locus_tag="KRQ43_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH2740470.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            98367..99074
                     /locus_tag="KRQ43_000089"
     CDS             98367..99074
                     /locus_tag="KRQ43_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH2740471.1"
                     /translation="MNNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRKLIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVIGYQGEVSKEQN
                     LEKLFMKVVAENRKRGE"
     gene            99076..99792
                     /locus_tag="KRQ43_000090"
     CDS             99076..99792
                     /locus_tag="KRQ43_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH2740472.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWAGKMIYCIICCSIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLTNMFFT
                     IVGVAVFSTTEMWYVFPYSIPSRLMVVVLHILPNGLPVPEGSELLNNAVILPGVLISV
                     ILFVLFALVTRAWFNNREVK"
     gene            99794..100552
                     /locus_tag="KRQ43_000091"
     CDS             99794..100552
                     /locus_tag="KRQ43_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH2740473.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            100696..102084
                     /locus_tag="KRQ43_000092"
     CDS             100696..102084
                     /locus_tag="KRQ43_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HBH2740474.1"
                     /translation="MLRSKKSNNKKVEKLRTIFIKYLSLFFVMTISFALLLMLSFSVL
                     LSSGVILPANYSEKQFDKYKEKIISSEKAIEDIIPNLYEYGVYTLDGNLISGTFNKKE
                     SKQVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKLVSEYSSPVLRAYLPKPEMLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNILF
                     SMDKMKLALKNSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAINMSEFIKDVLLQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVSNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(102160..102981)
                     /locus_tag="KRQ43_000093"
     CDS             complement(102160..102981)
                     /locus_tag="KRQ43_000093"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HBH2740475.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            103217..104386
                     /locus_tag="KRQ43_000094"
     CDS             103217..104386
                     /locus_tag="KRQ43_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBH2740476.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSEDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            104569..104769
                     /locus_tag="KRQ43_000095"
     CDS             104569..104769
                     /locus_tag="KRQ43_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH2740477.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            105190..105618
                     /locus_tag="KRQ43_000096"
     CDS             105190..105618
                     /locus_tag="KRQ43_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH2740478.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(105761..106516)
                     /locus_tag="KRQ43_000097"
     CDS             complement(105761..106516)
                     /locus_tag="KRQ43_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH2740479.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(107217..107723)
                     /locus_tag="KRQ43_000098"
     CDS             complement(107217..107723)
                     /locus_tag="KRQ43_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740480.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            complement(107805..108125)
                     /locus_tag="KRQ43_000099"
     CDS             complement(107805..108125)
                     /locus_tag="KRQ43_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH2740481.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            108294..108491
                     /locus_tag="KRQ43_000100"
     CDS             108294..108491
                     /locus_tag="KRQ43_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740482.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            108596..109036
                     /locus_tag="KRQ43_000101"
     CDS             108596..109036
                     /locus_tag="KRQ43_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740483.1"
                     /translation="MENKKDILFKETDERLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            109285..109728
                     /locus_tag="KRQ43_000102"
     CDS             109285..109728
                     /locus_tag="KRQ43_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740484.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPIMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTITLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            109733..110797
                     /locus_tag="KRQ43_000103"
     CDS             109733..110797
                     /locus_tag="KRQ43_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBH2740485.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTEEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            110811..111239
                     /locus_tag="KRQ43_000104"
     CDS             110811..111239
                     /locus_tag="KRQ43_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH2740486.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            111353..111799
                     /locus_tag="KRQ43_000105"
     CDS             111353..111799
                     /locus_tag="KRQ43_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH2740487.1"
                     /translation="MNENGLSKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            111826..111993
                     /locus_tag="KRQ43_000106"
     CDS             111826..111993
                     /locus_tag="KRQ43_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740488.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            111993..114446
                     /locus_tag="KRQ43_000107"
     CDS             111993..114446
                     /locus_tag="KRQ43_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740489.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASSRVNSLNSSLRKVQTTASSVSSTMAKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKRVEKRPYQGSINLKDMVSSAMARILPKLMLFKNT
                     FWSGVIAIKDMASSIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKTSQKDVDKYYDSLVNMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSSKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            114446..114868
                     /locus_tag="KRQ43_000108"
     CDS             114446..114868
                     /locus_tag="KRQ43_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740490.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEVATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            115150..116679
                     /locus_tag="KRQ43_000109"
     CDS             115150..116679
                     /locus_tag="KRQ43_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH2740491.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            116695..117021
                     /locus_tag="KRQ43_000110"
     CDS             116695..117021
                     /locus_tag="KRQ43_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBH2740492.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            117021..117449
                     /locus_tag="KRQ43_000111"
     CDS             117021..117449
                     /locus_tag="KRQ43_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH2740493.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDVLSANVKVSTIYGEVEINV"
     gene            117442..118494
                     /locus_tag="KRQ43_000112"
     CDS             117442..118494
                     /locus_tag="KRQ43_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH2740494.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGENNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            118491..119189
                     /locus_tag="KRQ43_000113"
     CDS             118491..119189
                     /locus_tag="KRQ43_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBH2740495.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSEMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            119190..120176
                     /locus_tag="KRQ43_000114"
     CDS             119190..120176
                     /locus_tag="KRQ43_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH2740496.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGDTDILTTDSKDLSGAINEVVKKIENISFDDVISGQIQTDISVLKNSY
                     NKLSEKVLDILIYLELESEVTVDEAGYWYDTLANGNNIVAIEGLKLDLNRKCITGEIG
                     NVIFRDVVLPFSANRVRYIHDMDNNFVETKSSNTYLKEQKDITLSKYSYEIR"
     gene            120198..125375
                     /locus_tag="KRQ43_000115"
     CDS             120198..125375
                     /locus_tag="KRQ43_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome condensation regulator"
                     /protein_id="HBH2740497.1"
                     /translation="MKQNKLLQRGAYFNDKNILIDDFDKRYNDYDFVEFFTGISNSTF
                     GLKSDGNLYACGDNTGFQLGLGKDSSERRMFSKVKIDNVKYVSCGSKHSVAVTKDGFA
                     YGAGTSNVGQLGVIESTVYYEFTKLPIDDVKTVACGYDFTFVLKNDGTLYSAGLNSSG
                     QLGLGDTNNRATFTKVNIDSVKDVVTYNQSVFIIKMDGTAHACGLNSNGQLGINSTLN
                     KSVFNKIEGMDNVKQIACGSSHTILIKNDGTMYTTGYNGVGQLGTGNNNNSIVFTLSS
                     INNVKYASCGNNHTMILKYDNTLFSTGQNNYGQLANANKDVASRNTFAKVNVENIKDI
                     KCGSQFNFLINGSKEIFVSGCNLAGQLGSFFHTTFLYEFSNVQSSNLDNYSGLLVNDD
                     YLYVTKDNSEFLNVKLSDNFQDYKKIELTDSNMFIVMNDGTLYACGLNNYGQLGLGDT
                     VNRSVMTKVDIDNVLDIKGNGNSTFVLKNNGTLYSCGLNSNGQLGLRDEVNRNIFTKI
                     EIENVKDFCVGSNYVIALNHSKEVYGWGNNPYNNIEKTSNYPYKQGISNIEKIAAYDY
                     SVYMINSEGKLYVSGYNYNYQLGKGNNSNQSKALVSQCRTNSTSSTSNGLRTLPKITN
                     VFPFYDGCAIIDEGGYVYLTGYHGYLRTLNSSPSISDYSRYGTFIEATNSNHNTYFIQ
                     ETDFSGIEKVIGMSNNILFFKKGSSYITGYPKTFGSTITGHRSYTSINSESSNLGSNF
                     IIYHSNSKLYGKGIANSGQFGNSTNIDGTSNYDTGLKDIKDIIVKGNTVVVVDKNNNI
                     YVTGMNQNNKLGIGEYNNEPVKKFTNITEQSNSFIFMDDIKEITTSRNTMFIVKNDGT
                     AYATGNNSSGQLGLGDTINRNKFTQINLDNIKKISTSIDGNTTFAIRNDGTLYSTGLN
                     TKGQLGLGDIVNRNTFTKVNIQNVRDVVLGTTHSHAIKDDNTLYSCGENTHGQLGLGS
                     ESNHPDVLTFTVNNITNVRDVYCSDTTTFIVKDTNIAYCCGYNNNSQLGMGNTTDQYS
                     FIKCMENVKEVIPNEINTYIITIYNTAYSTGLNTDYCLGLNSNSNQSSFSEIPISNVV
                     KVAPNRNNAVLLLTSEGDVYTAGKCSNGSGTGSETPEKIKKIASKAKDIGMNYRCGHY
                     VSDNGDLYGTGFNNNGQLGVGDVTKRDTFIKTNTRVKKILPLEYANIAIKDTNDIYIC
                     GLNNYGQLGVGNRYDSRNNDNRIFNYKHMNFVMGDLTSIKNRHNFILLNNKIVIPTTK
                     DIDYGLVLGNLYKGDLYTELPYEDIKEVSISKTHIIILLNDGTMYGCGTNYHGELLQD
                     LSINQVDEFVQINVSDVKHVSCGDNFTYFIKSDDSLWSIGKNSEYQLGIGHNNPVTEL
                     QRITTISSCKEVHCGKNYTLVVTTGNELFVQGYNDKGALGLGSDSENTIIKFFTKALT
                     DIREIKSYGSDHILVLKNDNSVWVTGKNRDVYKIEQPVEFLKEFTIVPISEDVNTVKD
                     VLATDNTLYIISEVGTTNAAIEITEKSISSIKIKIQDPNKDISRIEMLINGESVKSVS
                     DLTTEKISFEVPPDKIKIGENKILFRAYCKGDDLYASLFIFKESTGNSIIKDSYVMIG
                     NRMYKVVNTTSNEQDITITLDRGLEEDLNLGDPIYQLINKTKVQVKINKSDLFKDMKL
                     VEIKKSDSSYQEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            125392..125745
                     /locus_tag="KRQ43_000116"
     CDS             125392..125745
                     /locus_tag="KRQ43_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740498.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQAKQDDDITNNFI
                     ANAEIYEMLLSQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGRKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            126008..126268
                     /locus_tag="KRQ43_000117"
     CDS             126008..126268
                     /locus_tag="KRQ43_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740499.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(126493..126948)
                     /locus_tag="KRQ43_000118"
     CDS             complement(126493..126948)
                     /locus_tag="KRQ43_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740500.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(127176..127595)
                     /locus_tag="KRQ43_000119"
     CDS             complement(127176..127595)
                     /locus_tag="KRQ43_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740501.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            127894..128103
                     /locus_tag="KRQ43_000120"
     CDS             127894..128103
                     /locus_tag="KRQ43_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740502.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            128135..128344
                     /locus_tag="KRQ43_000121"
     CDS             128135..128344
                     /locus_tag="KRQ43_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740503.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(128561..128959)
                     /locus_tag="KRQ43_000122"
     CDS             complement(128561..128959)
                     /locus_tag="KRQ43_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2740504.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMMILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(129380..131872)
                     /locus_tag="KRQ43_000123"
     CDS             complement(129380..131872)
                     /locus_tag="KRQ43_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2740505.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSINQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            complement(131886..132428)
                     /locus_tag="KRQ43_000124"
     CDS             complement(131886..132428)
                     /locus_tag="KRQ43_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2740506.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            132671..134185
                     /gene="glpK"
                     /locus_tag="KRQ43_000125"
     CDS             132671..134185
                     /gene="glpK"
                     /locus_tag="KRQ43_000125"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH2740507.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            complement(134299..134928)
                     /locus_tag="KRQ43_000126"
     CDS             complement(134299..134928)
                     /locus_tag="KRQ43_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2740508.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            135517..136308
                     /locus_tag="KRQ43_000127"
     CDS             135517..136308
                     /locus_tag="KRQ43_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HBH2740509.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRSVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV"
     gene            136337..137557
                     /locus_tag="KRQ43_000128"
     CDS             136337..137557
                     /locus_tag="KRQ43_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HBH2740510.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVDTMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            137577..138272
                     /gene="pxpB"
                     /locus_tag="KRQ43_000129"
     CDS             137577..138272
                     /gene="pxpB"
                     /locus_tag="KRQ43_000129"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBH2740511.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            138302..139288
                     /locus_tag="KRQ43_000130"
     CDS             138302..139288
                     /locus_tag="KRQ43_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HBH2740512.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRSKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLNSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(139507..140073)
                     /locus_tag="KRQ43_000131"
     CDS             complement(139507..140073)
                     /locus_tag="KRQ43_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740513.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            140425..141492
                     /locus_tag="KRQ43_000132"
     CDS             140425..141492
                     /locus_tag="KRQ43_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HBH2740514.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESVILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEESKDISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            141511..142671
                     /locus_tag="KRQ43_000133"
     CDS             141511..142671
                     /locus_tag="KRQ43_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH2740515.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEETELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            142684..144780
                     /locus_tag="KRQ43_000134"
     CDS             142684..144780
                     /locus_tag="KRQ43_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HBH2740516.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGFNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTKEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(144939..145283)
                     /locus_tag="KRQ43_000135"
     CDS             complement(144939..145283)
                     /locus_tag="KRQ43_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH2740517.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            145575..146465
                     /locus_tag="KRQ43_000136"
     CDS             145575..146465
                     /locus_tag="KRQ43_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH2740518.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            146683..147969
                     /locus_tag="KRQ43_000137"
     CDS             146683..147969
                     /locus_tag="KRQ43_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH2740519.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDICEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKKFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(148058..148501)
                     /locus_tag="KRQ43_000138"
     CDS             complement(148058..148501)
                     /locus_tag="KRQ43_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HBH2740520.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(148525..149319)
                     /locus_tag="KRQ43_000139"
     CDS             complement(148525..149319)
                     /locus_tag="KRQ43_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HBH2740521.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(149885..150361)
                     /locus_tag="KRQ43_000140"
     CDS             complement(149885..150361)
                     /locus_tag="KRQ43_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH2740522.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPNVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(150462..151631)
                     /locus_tag="KRQ43_000141"
     CDS             complement(150462..151631)
                     /locus_tag="KRQ43_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2740523.1"
                     /translation="MLNIRTLCHEINDWIINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKNYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            151794..152657
                     /locus_tag="KRQ43_000142"
     CDS             151794..152657
                     /locus_tag="KRQ43_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBH2740524.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDDLYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            152728..153321
                     /locus_tag="KRQ43_000143"
     CDS             152728..153321
                     /locus_tag="KRQ43_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HBH2740525.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(153572..154207)
                     /locus_tag="KRQ43_000144"
     CDS             complement(153572..154207)
                     /locus_tag="KRQ43_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH2740526.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNIHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(154287..155018)
                     /locus_tag="KRQ43_000145"
     CDS             complement(154287..155018)
                     /locus_tag="KRQ43_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH2740527.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLYMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQNNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            155349..157538
                     /locus_tag="KRQ43_000146"
     CDS             155349..157538
                     /locus_tag="KRQ43_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HBH2740528.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEYNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKKALPE"
BASE COUNT        62437 a        17350 c        27220 g        50807 t
ORIGIN      
        1 aagttaaaat gaaaaaaata taaaaaaata aagtatataa gagtataatt tgacttttat
       61 atactttttt atattatttt tgagtttttt aggaagatat tttacaagtt aagaaaacta
      121 taaggagtgt tatattgaat ataaaatagt ataatatata ttatgttaga taattaatat
      181 gaaaatatac aaatatataa aaaagtttgt ttagagttat agttaatgtg tgtattaatt
      241 taatactaat ttattggagg tttaaaaatg aaatacataa taaaaagaga tggtacaaaa
      301 gaacttttta gtaaaagtaa gattgaagat gctgtctata aagctagtat aaatagtgaa
      361 ggtggagtag atagagagtt ggcatatgat atatcaagaa aaatagctaa tgactataat
      421 tctatggaaa aatgcttatc cgtagaagaa atacaagata tagttgaagt actacttatg
      481 gaatcaaata gaaaagatat agcaaaacac tacatattat atagagaaag acgctctgaa
      541 ataaggacta aagcttggga gtttgatgaa ttacaaaaat caatatggaa gaacaagtat
      601 agacataatg gtgagagttt tgatgaatgg ataaagagaa tttcaaataa tagttcaaga
      661 atatcaaaac taataagaca aaaaagattt ctatttgctg gaagaatttt agcaaataga
      721 ggattacaga aagaaggaaa aaaagtaaca tattctaatt gttatgtaat agaaccacca
      781 aaagatagca tagaagatat atttgatact gcaaaaaaac ttgctagaac ttttagttat
      841 ggtggaggag ttggaattga tatttcaaag ctaagaccaa aaggagcgaa agttaacaat
      901 gctgcaaaac atacgactgg agcagtctct tttatggaac tttacagtat gacaactggc
      961 ttaattggtc aaagagggag aagaggagct cttatgattt ctatggatgt aaatcatccg
     1021 gagatagaag agtttataga tataaaaaca gatttggaga aggttactaa agcaaatatt
     1081 tccataaggg taacagatga atttatgcaa gctgtaaggg aaaaaaagtt atataattgt
     1141 acttttgaag ttgaaactac tggagaaaaa atagttaaga tagtaaatgc ttatgattta
     1201 tttaataaat ttgtgaaaaa taactgggat tatgcagaac caggtatatt gttttgggat
     1261 aaaataaaaa catataattt tatgagtgaa gataagaact tttgcttttc aggagtaaat
     1321 ccttgtgcag aagaaccact tccaagtgga ggaagttgtc tacttggctc aataaacttg
     1381 tcagagttta taatacaacc atttggtgaa catgctactt ttgatattaa taaattaaaa
     1441 tcttgcgtta gagaagctgt agtagcttta aatgatgtct tagatgaggg gttgaacttg
     1501 catccattac aagaacaaag agatagtgta cataagtata gacagatagg tttaggtgta
     1561 atgggtatag ctgatatgct tataaaaatg ggaataagat atggttctga tgaatcttta
     1621 gaactatgtg atttaattgg taagactatg ttaaatgaag ctgtgaagca atcagcatta
     1681 attgctaaag aatatggaac atttagtgag tataaatatg aaaatatttc taaatctaag
     1741 ttttttatag aaaatctaaa tgaagacact aaagaaatgg ttaaaaagta tgggcttaga
     1801 aattcacaac ttttaaccat acctcctaca ggttctatat ctacaatgat aggtatcagt
     1861 ggtggaatag aacctatatt taatctttca tatataagaa aaactgaaag cttgcatgat
     1921 gaggatgtgt attataaagt atatactcca attgttaaag agtatatgga caagaaaggt
     1981 attacagatg aagaatgttt accagatttt tttgttactg ctatgaatat aggatatgaa
     2041 gaaagaataa acatgcaaaa agtatggcaa aagtatattg atgcttctat atcatctaca
     2101 ataaatatac cttttgaaac tacagttgaa gatgttttca atatatatat taaggcatgg
     2161 gaggctggtc ttaaaggagt aacaatattt agagatggat gtaaaaggag tggaatttta
     2221 ataaatgaaa aaaaggaaga aaataataaa gaagataaaa aagaaaatag taaaaaagaa
     2281 tattataaaa ataataaaaa agaaaaagat aataaagatg aaaaagccaa agaaataata
     2341 aataaaaatt ttgaagaaga tgaaaaattt gtgtgccctg aatgtggaag tgaaggaatt
     2401 gcacatacag gtggatgtag tatatgttta aaatgtggct atagtggatg caattaaact
     2461 ctaattaaaa aattttaata tatttaaaaa ttaaattttt aaaaacgaaa gatgagggaa
     2521 tggtatgcag gataaaagtg tgagggagat taaagaaata atagagactt tagaagtaga
     2581 aaaatatatg gaatatatag aactgttaag agttgatgaa agaaaatctg tacaaggtct
     2641 agctataaaa ctagcaaaaa agctggataa tattagaaaa gaagaagaaa gattggaaac
     2701 tataaatata tttgagaacg aaggctatga taaaggttat ttgtatattg gaggaattga
     2761 tgaggcggga agagggccac ttgctggacc tgttgtagct tctgttgtag tatttaaaaa
     2821 agatacaaaa atagaaggtg taaatgactc taagaaactg agtgaggcaa aaagagatga
     2881 actttttgaa gtaataaaag aagaagcact agattatgga ataggtatag taaataatga
     2941 agaaatagat gaatttaata tattaaatgc tacatatatg gcaatgaaaa aggctataaa
     3001 ttgtttaaaa aaagcaccgg attatttatt agttgatgca gcaacaatac caggtattga
     3061 catatctcaa aatccaattg tgaaaggaga ttcaaaatct atatcaatag cagcagcaag
     3121 tatacttgct aaagttacta gggatagtat aatgtaccaa tatgatagag tatacccaga
     3181 atatgggttt aaatctcaca aaggatatgg aactaaagaa cactatgaag ctattgaaaa
     3241 atatggcata actcctatcc acagaaaaag ttttttgaaa aatatactgt aaatataata
     3301 tgatataatg tatataatat aaattactat agttaatggg ggattaaaga tggaatataa
     3361 tgaattatta aaaagtgcta gagaaaattt aaatggaagt tgtaaagttt gtaaggtttg
     3421 taatggggtt gcttgtgcag gtgaagtgcc tggcatggga ggtaaaggaa gtggttcttc
     3481 ttttatagaa aatagcaaga gtttagaaaa agtaaaagta aatatgagag taatacatga
     3541 tgtatcaaat cctgatacat ctatagagat gtttggaaag aaaatgagtg cacctatatt
     3601 tgcagctcca gtaacaggaa ctactttaaa tatgggtgga aaaattaatg aaagagatta
     3661 catagaacca gtagttgcag gatgtgctaa tagtggtatt tatgcaatgg ttggtgatac
     3721 ggcagtagat gcttttttaa tggaaaattt agatgtagtc aaaaagtata atggagctgg
     3781 aattgtattt attaaacctt gggataatga aaatattata aaaaagataa gattagctga
     3841 agaagctggt gcatttgcag ttggagttga tatagatgcc tgtggtctag taactttatc
     3901 attacatgga aaaccagtac ttcctaaaaa tgttaaacaa ataaaggagt tagtaaagtc
     3961 tactaaacta ccatttatat tgaaaggtat aatgactgtt gaagatgctt taatggcagt
     4021 agaagcaggt gtgtatgcaa tagttgtatc aaatcatgga ggaagagtgc ttgactgtac
     4081 accaggagca tgtgaagttt taccaaaaat tgctgatgct gttaaaggta aagttacaat
     4141 acttgcagat ggtggagtga gaactggttt agacgtacta aaaatgatag gtttaggtgc
     4201 agatgcagta ttaataggaa gaccttttgt gactgcttca tttggtggtg caactgatgg
     4261 tgtagaaact tatgtaaata aacttcaatc agagctaagt agttctatga tattaactgg
     4321 atgtcaaact ataaaagata ttgatggaaa agttatatac aaataaaatt ttatacaaaa
     4381 aagaggaaaa atcattttaa tgtagaataa ttgtacaaag ggggaattta tatgagtaga
     4441 aaagcttatg aagaagcctt agtagaatta gaaaaattta ttgatgaaag aaaagaaata
     4501 attaaaagtg cggaggactg tattgataag tacatagttg acagaacgct accttttgat
     4561 tacaaagata aatgtgtgga atggcaacaa gagttacttg atattgcaga ggcacaagtt
     4621 ttagaagcaa acgaattagg tgttttactg gaagagaaaa aagaacttga ggaagagtaa
     4681 gttttattac taaatctagg gaaaatcaag aatatgattt acccctagat ttttttattt
     4741 aaataaagat gtctatataa ttaatctatc tttatcaatg ttagattaaa aggtttgaag
     4801 aaaaatagag taattgtatg aatagttaaa caattaaact agtctataag accaatttaa
     4861 ttgttatttt ttgaatttag tatatggttt ttcatttctt ctaatacaat tgtgtaggat
     4921 ttgcattgtg ctgcagccaa ttctgacaaa gcaaaccttt gagccttatt tagaaagtcc
     4981 ttatctgtgc tacatagttg ttttgaatta tcttgtatca taagcatctt aattaatttt
     5041 acaatctcaa aaacatctcc tgaatgaaat ttatcatggt atagtttaag tcgttttttt
     5101 ctatcaaaaa cccataaaca atcaacctta tcaagggatt ggataaagtt ttcaacttca
     5161 ttttcatcca taattggacg tacaccaatc ttatcagcat ttaaaactgg aatcgaaatt
     5221 ttaagattac tattgtaaat aacagtcaat tcatagtatt tctgtatatg atgatttata
     5281 tcctttgtta caagaccact tatataacag gctccttctt ttggatacat tacactttca
     5341 ccgattttat acatatggtt atacctccaa actgaatttt agatattgca atttgggtac
     5401 aatgctttaa ttatctaata attaatatta tatcacgaaa tgcttgacaa gtcaaaaaga
     5461 ttaatatata ataaaaagtt tagaataata gatatatata attggctata aaaatataag
     5521 ataagaggat ttaatatatt aaaatatcta gttagtattg tataaaataa catactaact
     5581 agatttaata attattaatt tctagcaaaa tctcttaagt taagacttcc ggctgttaca
     5641 aataccattc caataagaat taaaacaatt atatttatta atatattacc attattatta
     5701 atagcatcta tagtccaata aaatggtgta agctttgaaa gattagccat aaaggataat
     5761 ttatcaagtg atggtatcat attagatatg gatatagcta aacctattaa agaataaaac
     5821 gtagacataa gacttataga accttcgttt ttaaacaccc tagctatcca aaatacaaat
     5881 ccagtagcaa caaaactatt tgctagtaca atcatcaatg tatttagagt caatttaaaa
     5941 ttacttatag atgtgaaaca tactaaagtt aaggtgtata caattgcttg agtaaaaaat
     6001 aaccctaaaa atatgctgaa aattattttt atatcattat gctttgtaga aacaagtctt
     6061 tttaaggtat tagatttctt taatgaaaat aaatcagaag ctagatgtgc tgcattaatg
     6121 tacatgaaat aacatatcaa gaaaactatt aaaaatgaat ttttattctt acctgaactg
     6181 ttatcaatta tatttgtctt ggtcaattta tcatctatat ttctatctat ttttaatttt
     6241 aatgaattag taataaaaga ttctatttgt gattctgccc aaagactacc tccaccattt
     6301 tcagttttaa aacatttaac ctcaggtcgt tttaagttat ctatattgct tgaaaagttt
     6361 ttatctaaaa tgaagacagc agaaacttta ttatttttta atagatccat agccttgtct
     6421 tgttcgttta atccaaatga gttttctttt aatttagaac tatctattaa cttatgttcg
     6481 tattttccag aagaattgga tacaatcgct actggagaaa agtacattga ttgattttct
     6541 gagttgccag taaaaaagtt aagataaaac attaatataa caggaaacaa aaccatatta
     6601 actaaaagag catgattttt tatatatctt tttatgtttg caatagtcaa cctaatcatt
     6661 attaaacctc cctccattta tatttttctt ttacaataga aagtgcaatc aatactgtag
     6721 atgcaattag gcatgtaaaa attaaacttt ctattgaatc tatagtttta aacgtctcat
     6781 aattactgaa caatgttcct attaaataag taggagataa acttgtaaac ttagtaaaca
     6841 catcatttac tatgctgaaa atacctccaa aaactgtttg caagaagagt aatgcataaa
     6901 ctataactgt accatatttc ttgctaaaaa aggtagttat aaaagtagat attgaagtca
     6961 taaaataaga agctaaagca caaagtaaag ctaatataac aaagttacct ttgaatgtta
     7021 caccgagtgt tctaaaaaat aaaacgtata atgataaaaa tataaatgag taaatccaga
     7081 aacctataaa atcataaatt aaaaattgta ctctagttac aggtatagag tagagtcttt
     7141 ttgaaagtcc ttttgattca cttacataat ttgataaaat gctattcatt ataaaaatta
     7201 ttgcgaagaa tccaagggaa actaaagcaa agtactcata agagttttgt ttaacattat
     7261 tttttattat agaggtatca atagaattct tattaaataa ttttgagaaa tcttctgaac
     7321 ttaatttttg agaattattc agatataatt tttcatgata agtatctaat atatcttgaa
     7381 gtaatattgc aatattatca ttagatttaa gtttttctat acttagatta tttgattttt
     7441 catttaataa attattctca tatcctttag gtatagtaag ttttaagtct gccttagaat
     7501 catctttttg aactgttaat atagaagata aatcgttttt tagatatcct gtcaaattac
     7561 ttgatagctt tgtattatct ttatcatata taacaattga tgtcaaatct gtttttatag
     7621 gattttgaaa tatactttct gtcaccatcc caagaaatcc agctaaaact agaggtaagg
     7681 ctaagaaata tattaaatta agcataaagg agctttttaa aacttttagc atagttttta
     7741 cactaatgta caatttcatg aaatcacctc cattagtccc ttaaattttt acctgttaga
     7801 tttaaaaata cgtcttctaa actaggttct tcataagata ttcgtgttat ttttgaatta
     7861 tttttgtcaa caacagataa tacatctgta agttgtaatt ttttgtctac acctaattct
     7921 aataatgaat tattttctaa aatagataca acacctttag tattttttaa atcaaatata
     7981 agttgagcat ttatattttt tatttccata attaattttg tatttgtaga tactaatgat
     8041 tttaaataat cattatctcc aaaagcaatc tctttacctt catccataat aaaaatctta
     8101 gaacaaagat gctcaacttc ttccatataa tgagaagtat atattactgt ggttttttgc
     8161 tttttagata tattttttat aaaattgaaa atatggtttc ttgattgcgg gtcaacacct
     8221 acagttggtt catccaatat taatatttta ggatgattta aaagtgctat tccaatgttc
     8281 aatctccttt gcataccacc agataatttt ttgatttttt tctttttaac atcagtgagt
     8341 cctgtgactt ctaaggcttc agttattctc tcttgaagca attttccctt tagtccatag
     8401 taagtgccaa agtactctaa gttatcaaaa ggagtaagag tctctataag tgctaattct
     8461 tgtggaacta atcctattat agactttgct tttatacaat cttttgacaa atctaaacca
     8521 ttgatttgga tgtcgccact atttggtaac ataagatttg taattatatt tataagtgta
     8581 gatttaccag caccattcgg tccaataagt ccaaatatct ctccttcttt aacagaaaag
     8641 ctgatattat caagtgctaa tttatcatta aatctttttg ttatattatt tactcttact
     8701 atatccataa taattcctcc caaaataatt ttgtataagt taaaaatcta taatactata
     8761 ataaagaatt atgaatcata attctattac tataagtcac taaaaaaagt gacttaagtc
     8821 actttatatt ttcatttatt ataaatgagt ttgtgagtaa gaaatttcta gggtatagat
     8881 ttcttaccta tatatttata ttacaatttt atttttgaag gcaaatataa ctagttgtgt
     8941 cctatcacga agctctagtt tccctaagat attggtgata ttattcttta ttgtaccttc
     9001 agataagaat aattcttggc tgatttcttt gttgttaagt ccatttgcga ttaatctaat
     9061 tatggatatt tctttttctg ttaaattata catatcagaa atatgttttt gttctatagt
     9121 tttttgaggg tacataattt tttcagccac acttttatca agtacaatat ttccaaaaaa
     9181 cgaggaacga atcccttcat gtaatacttc atccgaacta tcctttaaaa gatatcctga
     9241 agccccaaat ttcatagcat cttctatgta ctcatcatca ttaaaggttg tcaaaattaa
     9301 taatgctata gagctatcat attcttttat aagtcttgtg cctagaactc catcacaaac
     9361 tttcatccga atatccataa gaactatgtc tacatcattt gttttacaaa attctaatgc
     9421 ttcatatcca ttggaagcat ctcctacaat ttctaaatcg tcataagatg ataaaataat
     9481 gttaagacct tttctaatca atttttcatc atctactata agaactttga ttttattcaa
     9541 aaaaatcacc tcctgaaaat ttaggaaaag acgctctaat tgtgaatcca gtattagaat
     9601 tatcgaattc aactttacca tttaattcat atattctttc gctaatactg ctaagtccat
     9661 ttcctctttt tatattgtta caccctatac cattatcgct gatagtaatt ataagatttg
     9721 aaggattaaa tgttataaaa attctgattt cagttgcttt tccatgtctt gatgcgttgg
     9781 aaagagattc ctgaacaagt ctatataaag cgatagattg atttgtagat aggttccagg
     9841 tattttttga tatagttaat ctaacgttga tatttgtaag tttaataaag ctattaacca
     9901 gttctctgat tttaagtaaa ttttggtaat tttcatattc aatgggtttt agttcagata
     9961 tagctcttct cacatcttga aaactttcag ttacaaactc tctaagttca tgaactaaat
    10021 cagaaatgag aggtttgtct tttaagagtt tttctatagc atttaattgg attatcgtcg
    10081 tagaaagaga atgtcccaca ctatcgtgta tttccctcga tatacggttt ctttctttca
    10141 aaattgctaa ctcttctata gaatttgcat aaatctctaa atcggcatta gcttttttta
    10201 attcatcttt agaaaccctg agtttgtcat aaagactttg attgtataat ttagataaat
    10261 tctcgttttc tagatacaca gaaaagaggg ttataattag taatgtagaa cttgattcta
    10321 gtgctaaata taaattttta tctaaaccaa taataaaaga aaatattata actaaagaga
    10381 ataatatata tttatatttt tcctttatta aaaatgaggc atccaaaatt aaagaaacat
    10441 agtaaagtgg attaaaagtc tttatatact tacaaaatat aaaaattaga ataagctcta
    10501 aaaaataaga aataagtata aatttattct cacttgataa agaaaaaaat ctaacttgat
    10561 tatttattat tagaaataat ataatcattg ttatagctgg atacaatgta ttttcagtat
    10621 ggtttaaata acttataagt aatataaata gagataaata tcgtataaaa ataaatgttt
    10681 tttttctgtt cattaaagac attcctccat aaaaataaac tttcattata aaaactagca
    10741 taatatcata aaagaataaa gtcaatagaa gtatttatta atatcaatgg aaataaaatc
    10801 aatttcaaaa aattgaatag ttaaattgta tactgacgat aatttaaaag taaaaattta
    10861 atatattgga gtagataatg aataataaag aaaaaggtga ttttggagaa gaaatagcag
    10921 ttaattatct gctatcaaaa ggtgcaaaga tactagaaaa aaattataga ttaaggatag
    10981 gggaggtaga tataatagca aatataggag atgaagttgt atttgtggag gtgaaatcaa
    11041 ggtctaacat aaagtatggc tacccttgtg aatctgtaga ttttaaaaaa agaaaaaaga
    11101 taattggtgt cgcaaaatac tatattataa aaaataactt aaataatact cccataagat
    11161 ttgacatcat agaggtctat ttgttagaaa aaagaataaa tcacataatg aatgcttttt
    11221 aaaaaagata atgtttttgg aaaggattaa atatgttaag tattattaat tcaagcaact
    11281 tagtaggaat cgacagcttt ttagttaagg ttgaagtaga tgtaagcaat ggaataccta
    11341 gttttaatat tgttggtctt ccaggcaaag aaattaaaga agcaagagaa agagtaaagt
    11401 cagcaattct taatagtgga tataaatttc caagcacgag aatagttgta aatttatcac
    11461 cagcagatat aaaaaaagaa ggagcttttt tagatttatc tataagtata ggccttttaa
    11521 gagagttaat aaaaaaagat gaaaattaca taagagaaag tatgtttata ggagaattat
    11581 cattagatgg aaaaataaga aaagtaagag ggatattgcc cataattatg ggtgcaaaaa
    11641 ctcagaacat aaaacgtatt tttataccaa ttgagaacat aaaagaaagt ctattagtag
    11701 atgaaattga tataattcct attaaaagtt taaaagaatg tgtcgatttt ttaaacgaag
    11761 agataaaagt cgataaagta agtataatgt cttttttgga tgataagtca agaaaagaga
    11821 acggagaatt agaaaaagat aatagttata tagattgcaa atatactaag attaataatg
    11881 aagaaagtaa atatgatgaa gactttaaag atgtaaaagg aaattatttt gtaaagagga
    11941 gtgcagaaat tgcagcagct ggaaatcata atatgtttat gattggacct ccaggctcag
    12001 gaaaaactat gattgcaaaa agagtaagga caattttacc agatataagt atagaagaaa
    12061 tgatagaagt aagtaaggtt tatagtatat tgggtatgat aaatgaaagt aaaggaataa
    12121 ttgataaaag accttttaga gcacctcatc atacaactac aaagcaatct ttaattggag
    12181 gaggaatgga tgcaagacct ggagaaattg ctttagcaca tagaggtatc ttatttttag
    12241 atgagatagc cgaatttgat agaaaaatac ttgagacttt aagacaacct atagaagatg
    12301 gatatgtaaa tatatccaga gtaaagtaca gtgcaaaata tccttgtaga gtactgttag
    12361 ttgcagctat gaatccatgt ccatgtggtt attatatgtc agagacagag tgtagatgta
    12421 gaagtaacga aattgataga tacataaata aaatatcagg tccattgtta gataggtttg
    12481 atatttttgt agaagttaat tctataaaat attcagattt taattcttta aaacaagaag
    12541 aaagctctca aaaaataaag agaagagtag aaaatgctag aaaaatacag ataaatagat
    12601 ttaagaaaga taatataaaa aataatagtg aaattaaagc ttacaattta tttaaatatt
    12661 gtaaactgga aaaagaagct tcaaaaacgg ctgagatgat atttaataaa tacaacctaa
    12721 gcagtagaag ttatacaaaa cttttaaaaa tggcaagaac aatagcagat ttagaagaaa
    12781 gagacttgat aaattcacag tgtattatag aagctttttc atttagaaag gcttattata
    12841 gttattttaa atagtttttt gaggtggatt ttatggaaaa aagagatact tatttatggt
    12901 taaaatcaat tggtggaata acaacaaaaa caattgaaat aatagaaaat gaaatagtaa
    12961 atattgaaga tatatttgat ttttctgaaa aagaaatata taatttaaaa aatataagct
    13021 tgaatattag aaaaaatata gtaaaatata gaggttacgc ttatttagaa aatataaaag
    13081 aactacttta caaaaaagcg attaaatata tttgtaaata tgataaagaa tatcctgaaa
    13141 atttaaagaa tatatacaac gctccaaagt tattattcta caaaggtgac ataggtttag
    13201 ttaataataa ttttaatata gctatagtag gttcaagaaa acctacagcc tatggaatta
    13261 attgtgcaaa aacaataagt tgtcaactat cccaatatgg agttaatata gtaagtggat
    13321 tagctatagg aatagatgca tactcgcaca taggttgtat gagtggaaaa tctaaaacta
    13381 tagcagtact tggttcagga gtagacaatc ctcttccaaa acaaaattta catttatcaa
    13441 ataaaatatt agaaaatggg ggattattat tatcagagta taatattaac tcgacagtag
    13501 ccccgtacca tttttctaat agaaatagaa ttatcagtgg tttaagtgat ggagtagttg
    13561 ttgtagaagc agcaataaaa agtggtgcac taatcacagt agattttgct cttgaacatg
    13621 gaaaaaatgt ttttgcaata cctggtaata taaattctca aatgagtaga ggttgtcata
    13681 aaattataaa agaaggtgca aaattaattg aaaatataga tgatatttta aatgaatata
    13741 acatatttaa tattattgat aaaaaaataa atcaaaaata tgataatata agtctaaatg
    13801 ccaagtctaa gcaaataatt gaagctataa aaagagaagg aaacttgcat atagatagta
    13861 tttgtgatta tactggtata gaaataaagt atgtaaattc aataatcaat gaattagtac
    13921 taaatgagtt agtagtagaa atgaataata aaacgtacag tttaaatgta taaattaaga
    13981 ttaggtagtg ggggtgtatg gttttatggc caaaacatta gtcatcgtag aatcgcctgc
    14041 aaaagctaaa actatagaaa aatttttagg gaaaagtcat tacacagtta aagcatcagt
    14101 tggtcatgtc agagatttac ctaaaagtaa attaggtgta gatatagaaa ataattttga
    14161 acctcaatat ataaatataa gaggaaaagg cgatgtaata aaagaattaa aaaaagaagc
    14221 taaaaaatct aaacaagtat atctagcaac tgaccctgat agagaaggtg aagctatatc
    14281 atggcattta gctcatatac taaatttaga tgaatctgag gattgtagaa tagagtttaa
    14341 tgagataact aaggatgcaa ttaaaaaagc aattaaacat cctagaaata ttgatataaa
    14401 tttggttgat gcacaacagg caagaagagt gctagacaga cttttaggtt atcaaataag
    14461 tcctatatta tggcaaaagg ttagaaaagg tcttagtgca ggtagagtgc aatctgttac
    14521 aacaaagtta atttgtgata gagaaaaaga aataaaggca tttattccaa aagaatactg
    14581 gacaatagat gttgaggcta agacagtaaa agacaaagat ataactttga aattttatgg
    14641 taaaaatgat gaaaagattg aattagaaaa tgaagaagct gtaaatgaaa tactaaaaga
    14701 aatggaaggt aaagatttaa aggttgagaa gatagaatct aaatcaagac gtaaatcagc
    14761 tccaaaacca tttacaacaa gtatgcttca acaagaagga gcaaataagt tattttttac
    14821 tactaaaaaa acaatgatga tagcacaaga attatatgaa ggtatcgaca tagaaggtga
    14881 aggtactgtt ggtcttatat catatataag aactgactct aaaagaatat ctgatgaagc
    14941 aaaagaaaaa gctaagggtt atatcgtaaa caatttagga gaaaactact ataaaaacac
    15001 tggtgataaa aaagaaaaaa aggatactaa aaaggttcaa gatgcccatg aggcaataag
    15061 accaacctca gttgatagaa ctccagagag tataaaagcc tcattgagca aagaccagta
    15121 caagttatac aatttaattt ggagaagatt tgtagctagt caaatggaag attcagtgtt
    15181 tgatatacta aatgtagaat gtaaaatagg cgatattgta tttaaggcaa ctggttcaaa
    15241 aatgaaattt gatggttata ccaaggtata taatttttca gaaagagaag acaaaatttt
    15301 accaagtata gaaaaaggag atatattaaa tatagaaaat atattgccag accaacattt
    15361 tacacaacca ccagcaagat atacagaagc tagtttagta aaaacactag aagaactagg
    15421 tataggtaga ccaagtacgt atgctccaac aatagctact atactgaata gagagtatgt
    15481 tgaaaagcaa ggaacaagtc tatgtccaac agaacttgga ataatagtta ctgatatttt
    15541 ggaaaataat ttccataaat ttatagatgt agattttact gctgatatgg aaagtaaact
    15601 tgatgttata gaagaaggca atacagattg gaaaaagatt gtatcagaat catatgcacc
    15661 acttaaagag gctattgaag aagctcttga aaatatagaa aaagtaaata tggatgaaga
    15721 aactgatgag atttgcgaga actgtgggtc taatatggtt atcaaatatg gtagatttgg
    15781 aaagtttatg gcttgtaaaa actatcccga ttgtaaaaca actagaccaa ttatgaataa
    15841 aattggtgtt aaatgtccaa aatgtgaaga aggagatatt atacttagaa aatctaaaag
    15901 aggtaaagct ttttatgggt gttctaatta tccaaactgt gactttgtag cttggaataa
    15961 gccaacagga gagttttgtg agaagtgtgg ttcatatatg gttgaaaaag tgactaaatc
    16021 tgaaacaaaa acagtgtgtt ctaataaaga atgtaataaa gagacaaaag agcataatga
    16081 cggaaaagag tgaaaattga aaaaaatcac ataattctct tgaaaaaggt tccaatctat
    16141 gataatcttt caagtgtaaa caactaatag aaaaataaat tttcattaaa tgtgaaaata
    16201 atattagaaa atataaaagg ttattaaaag gcctaaattt catgaggaga tgattaaatg
    16261 gcaagtgaag tgttacaaaa aacaaggaaa ataaataaaa cattacaaac aagtggtgga
    16321 agcagtgtct cttttgattt actggccgga gcattgggcg acgttttaag ttctaatgtt
    16381 tatgtagtaa gtgcaaaagg taaagtacta ggtcttcatt taaatgatgt tcaagacagt
    16441 tcagttatag aagatgagta tactaagcaa aagaaatttt cagatgaata tactcaaaat
    16501 gtgttaaaaa ttgatgaaac attagaaaat ttaaatggtg agaagatatt agaaatcttt
    16561 cctgaagaac atggaagatt acaaaaatat actacagtag ttccaatatt aggaagcggt
    16621 caaagattag gaacattggt actttcaaga tattcaaatt cattcaatga tgatgattta
    16681 gtaatagctg aaaacagtgc aactgttgtt ggtcttgaaa tattaagagc aataggtgaa
    16741 gaattagaag aagaaatgag aaagaaagct gtagttcaaa tggcaatagg cactctgtcc
    16801 tactccgagc ttgaagcagt tgaacatatt tttgctgaat tggatggaaa agaaggtcta
    16861 cttgtagcaa gtaagatagc tgatagagtt ggtataacta ggtctgtaat agtaaatgca
    16921 cttagaaaat ttgagagtgc aggtgtgata gaatcaagat cattaggtat gaaaggtact
    16981 catataagaa tacttaatga caaacttaca gatgaattaa aaaaattaaa aaacaatcaa
    17041 taatctatat tttataggtt tagattagaa aaggtatcta tttcaaatag ataccttttt
    17101 tagacgaatt attaaggtaa tgataagtat attaaaaagg agtgagaaaa tgcctttagc
    17161 agataaaata agaccaaaaa caatgaatga tgtaataggt caaagtcata taataggtaa
    17221 tggaaaaata ttgtctaaga tattacaatc taatttttta ccaaatatga tattttttgg
    17281 tcctcctggt gttggtaaaa ctacagtagc ggaaataata gcagaaagaa gcaataaaag
    17341 cttctataaa ataaatgcta ctaattcatc tttagaagat ataaaaaagg tgatatcaga
    17401 gcttggaagt ataaataatg taaatggagt cctattatat atagatgaaa tacaaagttt
    17461 taataaaaaa cagcaacaat caatattaga atttatggaa aatgggagta taactttgat
    17521 tgctagcact acagaaaatc catatcatta tgtatataaa gctcttttaa gtaggtctac
    17581 tgtatttgaa tttaaacctt tagaaaaact tgatatagaa aaaggactga aaagagctgt
    17641 tgaagtatta aatgaagata gctatatgga tattgagtgc aataataatg ctattgaaga
    17701 tatagcaatt ctttctgatg gagatatgag aagagcctta aatattttgg aagtggtagt
    17761 ctattcaact aaaccaaata aggataatat aacttatata gattcagatg taataagggc
    17821 atctacattt aataaaatta taaactatga caaaaatggt gatagtcatt atgatatttt
    17881 aagtgcattt caaaaatcta taagaggaag tgacccacag gcatctatac actatctagc
    17941 aagacttata aaaggtgggg atttgataag tatatgtagg agacttttag taatagctag
    18001 tgaagatata ggtttagctt atccaaatgc tattgtaatt gtaaaggcat gtgtagactc
    18061 agctatgcaa cttggatttc cagaagcgaa aataccatta gcagaagcta ctattctttt
    18121 ggctacatct ccaaagtcta attctgcatg tatagcaata atgaaagcta tggatgaact
    18181 ggataaagag tttgttaagg atataccaaa tagtataaag gatgctcact attctggttc
    18241 taaagaaata ggtaggggtt gtggatacaa atatcctcat aattttaaaa atcattatgt
    18301 aaagcaacag tatttaccag atagcataaa agatagtatt tattacatac cacaagaaaa
    18361 taaaactgag aaaaatataa aaaaatattt agaatatcta aatagtgatt tttagactga
    18421 attttatgta tcgggggtag atattatgat tataaaactt aactcaactt atcacagtag
    18481 agttatgaaa tacttaaaaa aagaacctga gtacaatttg tttataatag gggatattga
    18541 aagatatgga tatggaaata attttttaaa tatatgggca gacgtgggtg aacatggtga
    18601 aataaaggca atattactta aatattttga atttatgatg ttttattctg atggagagta
    18661 tgatgttgaa ggtttttata atctacttcg taatactaat tacgaagaaa tatctgggaa
    18721 aatatgtgct gtagatactt tagcaaagag attaggactt aataatttaa aggtagttga
    18781 tttttgcaaa cttcaaacta aaaagttttt gatagataat aattgtaatg caaaggttaa
    18841 gagaattagg cttggaaatc taaaaaagac agtgaaactt tatgacttaa tagatgaatt
    18901 tcacagtaca actttagaga atttaaaaaa tggactaagg acaggtagag gatattgtat
    18961 agagattaac aaacaggtgg tgtcaatggc aaagagtact tcagaaaata ggactcatgc
    19021 aatgataatt ggagtaggaa cacatcctaa atatagagct aaaggacttg ctacaaaatg
    19081 cctaattaaa ctatgttcag agttactgag agaaaacaaa attccttgtt tgttttatga
    19141 taatgaagag gctggaaaga tatataaaaa actaggattt gaaaacattg gaaaatgggg
    19201 aatttattca aaataaaaaa ttaaaattaa tcttgacaaa attagtaggg tataataaaa
    19261 ttatcttgaa agtaattcct actaaaacag tatgaattag atttctatat agaggtgata
    19321 atatatgaag ttgtctacta aaggtagata tggactaaaa gcaatgtttg aattagcatt
    19381 aaatcaagac aatggaccag tatcattaaa atttattgct aagaagcaaa aaatatcaga
    19441 tcagtactta gaacaaatat tttcatcttt aaaaaaatcg ggtctagtaa aaagtgtgag
    19501 aggtgctcaa ggaggttatt tgctttcaaa gaatgctgaa gacataacag taggagatat
    19561 acttgtagta ttagaaggac cagttgcatt atctgactgt gtactagatg aagatgtatg
    19621 tgaaaactca aacatgtgtg taacaaaaat agtttgggaa aagatgaaaa agggtataga
    19681 agatgttata gattcaatta ctcttaaaga tatgataaat gactataaca aaaataaatt
    19741 agaaaatgat ataacaaata ttaaaaaata gatttggaga tgaatgtaat ggaaaaaaga
    19801 agattgtata tggattattc tgcaacaaca cctattaaaa aagaagtatt ggatgcaatg
    19861 atgccatacc taacagatta ttttggtaat gcatctagtt ttcacacatt cggaagagaa
    19921 gcaaaagatg ctttggataa agcaagagaa caagtagcag cccttataaa tgctgaacct
    19981 agtgaaatat attttacagc aggtggttca gaaagtgata actggacact agagggtgta
    20041 gcttatgcta ataaaaacaa aggtaatcat ataataactt caaaaataga gcaccatgca
    20101 atacttcata catgtgaata cttagcaaaa catcatggat ttgaaataac ttatttagat
    20161 gttgatagcg aaggaagagt agacttaaga caactagaag attcaataaa agatactact
    20221 atacttataa gcataatgtt tgcaaataat gaaataggaa ctatacagcc tattaaagaa
    20281 atatccgaaa tagctaaaaa acataagata ttattccaca ctgatgcagt acaagctaca
    20341 ggtaatattc cagtagatgt taaagaatta ggaatagatt tgatgagtat gtcttcacat
    20401 aaaatatatg gaccaaaggg tgtaggagct ttatacataa gaaaaggtgt aagacttcat
    20461 aactttgtcc atggtggagc acaagaaaaa agcaaaagag ctggtacaga aaatatacct
    20521 gcaatagttg gatatggaaa agcagcagaa ttagctaagg aaaatatgca aaatcatgta
    20581 gaaactttaa ctcgtcttag aaataagtta atagatggtg tgttagaaag aataccttac
    20641 acaagagtaa atggtagctt agaaaataga ttgccaggaa atgcaaactt tgcattccaa
    20701 tttatagaag gtgaaggaat acttttatta ttagatatgt taggaattgc tggttcaagt
    20761 ggttctgcat gtacttctgg ttcattagac ccttcacatg tacttcttgc aataggttta
    20821 ccacatgaaa tagcacatgg ttcattaaga cttacagttg gagattttac aacagatgat
    20881 gatatagatt atatactaga gaacttacca aaagtaatag aaagacttag aagcatgtca
    20941 ccactttatg atgatgcgaa gaaacaaggt ttagtaaaat agacagaaag ataaagcata
    21001 aaaaatagac ataaattgag taggaggaaa agataatgca atatagtgat aaagttatgg
    21061 aacattttat gaatccaaga aatatgggag aaattgataa tgcaagtggt gtaggtgaag
    21121 ttggaaaccc tacatgtgga gatataatga agatattttt agacatagat ggagatgtaa
    21181 taaaggatgt taagtttaaa acatttggct gtggttcagc tatagcaagt tcttctatgg
    21241 caactgaaat gataaaagga aaaactataa aagatgcatt agaacttaca aataaagctg
    21301 ttgcagaagc tttggatggt ttaccaccag taaagatgca ttgttcagtt ttagctgaac
    21361 aagctgtaaa agcagctctt atagattatg ctcaaaagaa caatatccat ataccagaat
    21421 tggatggata tgttatagat gatgctcatg accatgatgt tgaagaagaa gaataaaaat
    21481 aagtgattgt gttatgagaa gtttacaatg attaaaaaga agtactaatg atataattag
    21541 gacataaaaa atagctgttt ttaaaatggc tattttttat tgcctaaatt aagtatttta
    21601 acttgattta gaggttaatt agttaacaaa ataatccata agattcaaat aataaagatg
    21661 attatttttt tagaaaatag aacaagctat attttaaata agtacaatac ttgctctata
    21721 tggtataata ataagtaatg caaaagatga ggtgaaattt gtttatgaat aaaaaagtaa
    21781 tgataggtat gagtggagga gttgatagct ctgtagctgc atatctttta aaacaacaag
    21841 gatatgatgt cattggtgtt actatgaagt tgtggcaaga tgatgatgtt gttgaaattg
    21901 aaggtggttg ttgctcttta tctgctgttg aagatgctag aagggtagca aataaaatag
    21961 gtataccatt ttatgtttta aattttagag aagtgtttaa agaaaaagta atagattatt
    22021 ttatagatga atatttggaa ggaaaaactc ctaatccctg tatagcttgt aataaacata
    22081 taaaatttga tgatttttat aagaaggcta gacaaatagg ttgtgattat gtagctacag
    22141 gtcactatgc aaagatagaa aaggatgaaa gtacaggaag atatttgcta aaaaaatctg
    22201 ttacagataa aaaagaccaa acttatgcac tttataatct tacacaagag caactagagc
    22261 atactttatt gccaataggt gactatgaaa aagatagagt aagagaaatt gctaaggaaa
    22321 tggggatggc agtacacaat aagcctgata gtcaagaaat ttgttttgtt aaagataatg
    22381 actatgcaaa ttatgtaaaa aaacattcta aaaagcgtat tgaagaaggt ttttttgtag
    22441 atactaaagg caatatactt ggaaaacata agggtatatt atattatact ataggccaaa
    22501 gaaaagggct tggaattact tttggaaaac caatgtttgt aatagacata aatccaataa
    22561 ataataccat agttcttgga gacaatgaag atttatttaa aaaggaactt attgctaaag
    22621 atgttaactt tatatcaata gatacgttag aagaaccctt aagagttcaa gccaaaataa
    22681 gatattcagc aaaaccatca ccagctacta ttcatagagt aggagaagat actattaaaa
    22741 tagtttttga tgaagctcaa agagctatta ctaaaggtca atctgtagta atgtatgatg
    22801 gagatattgt agtaggtgga ggtataatcg agaaaagttt ataaaaacat ctaaaaaatt
    22861 aaaaaaataa gcaataaagt atattaagag taaataaagt ttataaaata aatttattgt
    22921 atattaaaat atagtattga ttaattttgt aaaatttagt aatataatta gtatattaat
    22981 taaaaaacaa atacagtgat aaggaatagt aaaatatttg atgtcttaca gagagaggga
    23041 aatgctggaa gcccttagaa tatgatattt gaagcagcct tttagtagca atcttgaaca
    23101 atttatcttt tataaagaag atttaagtag agattgacgg tagttacgtt atagctaagg
    23161 ttttccgaag atatcatact ttgtatgata attagggtgg taccgcgatt gtcctcgccc
    23221 ctataaattt atttataggg acgaggtttt ttatttaaac gaaaaaataa aatttattag
    23281 gaggaacatg atatggaaaa gatgggatta aatgaaataa gaagtaagtt tttagaattt
    23341 tttgagtcaa aaggtcatta tgtagcaaat agttattctt tagtaccaaa caatgataag
    23401 agtttgttac ttataaactc aggtatggca cctttgaaaa actacttttc aggtgtagaa
    23461 gtacctccaa gtgtgagaat gtgtacatct caaaaatgta taagaacagg agatatagaa
    23521 aatgtaggta taactgcaag acatgctaca ttctttgaaa tgatgggtaa cttctcattt
    23581 ggagattact ttaaaagaga gtcaatcaaa tggggatggg aatttgttac agaatggcta
    23641 aatataccag aagataagat atgggtgact gtatatgaag aagatgatga ttcttatgat
    23701 atatgggcaa aagaaatgaa tttcccagaa gaaagaatgg ttagacttgg aaaagatgat
    23761 aatttctggg aaataggtac aggtccttgt ggtccttgtt cagaaatata ttttgataga
    23821 ggagaagaat atggatgtga caatccagac tgtaaaccag gctgtgattg tgataggtat
    23881 ttagaatttt ggaaccatgt atttactcaa tttgatagag atgaagaagg aaattatagt
    23941 ctattagaaa acaagaatat agatacaggt atgggtcttg aaagaatggg atgtattatg
    24001 caaggcgtag acactatctt tgaagttgat acaattaaat ctatactaga agcagttgag
    24061 aagttaacag gagtaaaata tggagagaat ccaaaaaatg atatatcaat aagaataata
    24121 actgaccaca taagagctgt aacattctta gttagtgatg gagtgcttcc atcaaatgaa
    24181 ggaagaggat atgttcttag aagactcctt agacgtgctg ctcgtcatgg taagttatta
    24241 ggagtaaaag aattattttt acagaaacta atagatgaag ttataaaggt aaatgataaa
    24301 gcatatccag ttttagttga aaaagaaagt tatattaaaa aagtagttgg aatagaagaa
    24361 gaaaaattca atgaaactat agaccaagga acagaaatat tgaactctta tatagaagta
    24421 ttaaaaaatg aaggaaagac tgtcctaagt ggtcaagaag cttttaaact atatgatact
    24481 tatggcttcc ctatagactt aactaaagaa atattagaag aagaacatct atctgtagat
    24541 gaagaagctt ttaatgaaga aatggaaaag caaaaagaaa gagctagaaa tgctagagga
    24601 aatatggatg gagaaagttg gaaggaagac cctctatcaa aattagaatc tacagttgac
    24661 agtacattta atgggtatag tgaaatttat ggtgaaggaa ctattgaagc tatagttaaa
    24721 gatgatgagc tagttcaaag tgcagaagaa ggcgataagg tatctatagt actagataac
    24781 actactttct atcctgaagg tggaggacaa gttggagatt gtggattgat aactaatgaa
    24841 aacttagttt tagaagtatt aaatactaaa aaaggtgcta ataatagtat aaaacatata
    24901 ggtataataa aatcaggaag aataagtaat ggggacaaag taaagacact cgtagataga
    24961 gaaactagaa tgtcagctgc aagaaatcac agtgctacac atttacttca taaggcatta
    25021 agagaagtat taggagaaca tgttaatcaa gctggttctt tagtaactcc agaaagactt
    25081 agatttgata ttactcactt tgaagcgata tcaaatgaag aattaaaagt aatagaagaa
    25141 aaagtaaata atgttatttt atcatcttta gacataaaat gtgatattat gaatataaag
    25201 gaagctaaag aaaaaggagc tacagcacta tttggtgaaa aatatggtga tgaggtaaga
    25261 gtagtttcta tgggagatta ttctacagaa ctttgtggag gaactcactt gacaaatact
    25321 tctcaagtag gaatgttcaa aatattatct gaaggtggag tagcagcagg tgtaagaaga
    25381 atagaagcaa taacaggaaa agctgtttat gaatacctaa aagaaagaga tggaattatc
    25441 tctgaagttt gtgtaaactt aaaatctaaa gaagataatt taattcaaag aataagttct
    25501 ttattagaag aaaataaaaa cttatctaaa gaattgcatg atatgaaagc taagatgagt
    25561 ttacaatcag ttgattctat ttttgattct aaagttgaag taaatggagt taatttgata
    25621 actaataaat ttgaaggtat ggatatggat acactaagag aaacagcaga taatctaaga
    25681 gataagcttg gttctggtgt agtagtactt gcaaatgtag tagatgataa agttaacttt
    25741 gtagttactg ccactaaaga tgtattagat aagggaatac attcaggtaa tattgttaga
    25801 gaagttgcaa aaatagctgg aggaaaaggt ggaggaagac ctaatatggc acaagcagga
    25861 gctagtgatg tatctaaggt tgaccaagct ttaagctatg caagtgaggt tattaagaca
    25921 caagttaaat aacattcact caaggaggtt tttagtttgg aaaaagattt agactacact
    25981 atgaaatttg aaggaatacc agaagatagg atgagtgtag gagatactat tgattttgta
    26041 tataaagcat tagttgaaaa aggatataac cctataaatc aaattatagg gtatctcctt
    26101 tctggtgatt ctagctatat aactagtcat aaaaatgcaa gagctataat taaaaaattt
    26161 gaaagagatg agatacttga agaagtaatc acgcactatc tgaatagaaa gtaggtcaaa
    26221 taaatgagaa aaaagattat gtcgttgttt gcaatagtca ttatgatttt tgtatcaact
    26281 gctagctatg gttttgctga agaaaaaggc aaggtcatat ttattgatat gaataggacc
    26341 aatcttggaa gtatgatgaa tattccaatc ttgaaaaatg agatagaaaa gagaggctat
    26401 gtagctctca tgaatataag aggggatcaa ggtactgatg atagaaggtc ttatgcaagt
    26461 atgggtgcag gaacaagagc tagtgtaact actgaagact atatcaattt tcaaaaagta
    26521 gaccaagata ctgctaaagc ttttgaagtc gcaacaggtc aaaaagctaa agaaataaat
    26581 gatttaggca ttaatagatc tataaatgaa aatcttgagt atggagaata tggagcaaat
    26641 ttagggtcat taggaaaaac tttatcagaa aatggtttaa agacatctgt aattggaaat
    26701 gctgatataa ttgaaaataa tcaattagtt aaaaatagaa acttatgttt agtagctatg
    26761 gaccaatatg gaaggattga ttcaggtaat attgataata ttaataagaa agattctaaa
    26821 atgccatttg gaatatctac agactacgat aaattactag atgaaactaa aaaatcctat
    26881 aaaaatagtg atgctatatt tgtagaactt ggagatacat atagattaga tatgtataga
    26941 ttaaatctaa atgataatac ttatggtaca atgaagaaaa atattgtaaa aaatataaat
    27001 aaatatcttg aacaagtatt ttctatggtt ggagaaaatg acactgttta tatagcaagt
    27061 gcatttccaa gtgacctaga ttataagaat aagagaagac tttctccaat aataaaattt
    27121 agtggagaag ggaaaggtct actggaatct gccacaacaa gaaaggctgg aattgttgcc
    27181 aatttagatg ttggagtaga tatactaggt acatttggtc ttgaaaataa agagatggta
    27241 ggtagaagtt atactttagt aaataaagag gacaatgttg gctatctaaa atcactttat
    27301 gaaaggatag tgtctatatc ttcaataagg tcaactatta taaatggctt tgtaggcgta
    27361 atatctgctt cttgggtaat tgccatgttt gcgattttct ttagaaatta tatgccacat
    27421 aaagagcgtg tattcaaagt acttaaggag tttataaaat taggcataat aatgccacta
    27481 tcatttatgt tagctccttt gatgaatttt aaaactccaa tttcaatatc tttgggaata
    27541 tttgcgacta cgctaatatt atacttgtta ggtagaaaat tatttaagga caatgatata
    27601 aagcacatgg gattttttgc aacacttact attttagtca tagttataga ttctgtattt
    27661 ggaacatact taatgcaaaa taacataatg agttatgatg ctgtcatagg agctaggtac
    27721 tatggtgtag gaaatgaata tgaaggtgta actatagcaa gtgcagtatt tggcttagca
    27781 gtattattac attataagaa ggtatctaaa ttacttgttg taattttttc gttaataata
    27841 cttataacta gtgcatatcc ttcaatgggt gcaaatgttg gtggagctat atcagaatgt
    27901 gtagcatatt tgttgtttat aatgcttata tatgacatta aaatagattt taagaaagct
    27961 gtattattag ctgtttcagc tgtagttgtc gtttttgcat ttgcagcttt agatatactt
    28021 tcaggtagtg aatctcattt aggtatgttt gtacagagaa ttttcctaaa tggaccagga
    28081 gagatattac aaacatttgg aagaaaaatt caaatgaata tgcaactagc acagacaagt
    28141 gtatgggtaa atattttact tgtaggaatt ggagtaattg cagtacttat atttaaacca
    28201 tctagacact ttagaaagat aatgaataat tttccaatct tgtttaaagg gtttattgca
    28261 tctatggttg gttgtataat tactctttta gttaatgatt ctggaatagt tgctgcatct
    28321 acagcatcta tatatatact tataccacta ataataataa atataaatat gataatattt
    28381 gaaaaaaaca actaaaaaat tttttactgt tcatatagga tttaaataaa aaatgcaata
    28441 tgattattaa tgtaaactgg atgcttacat aaaaaatcat attgcaattt ttatgattga
    28501 ttatgcaaaa ttctatgaag caggaagcct gtgaccttag ttatgagagg ttcagaatat
    28561 gtatttaatc tatagaatat aaatagataa aggaggaact atgttagatg gaagaataat
    28621 gggtcttgat gttggtgata aaactattgg agttgctgtg agtgatttga tgggattaac
    28681 tgcacaaggt gtaaaaacaa taaaaagagt tggcaagaaa aaagatattg aagagttaaa
    28741 agcaataata aaagaaaaac aagtaaataa aattgtatca ggattaccaa aaaatatgaa
    28801 tggaacttta ggtccacaag gagaaaaagt aatcaagttt tgtgaattgg taaaagcaga
    28861 aacaggtatt gatgtagagt tttgggatga gaggctttct acagtagcgg cagagaggtc
    28921 tttattagaa gcagatgtta gtagacaaaa aagaaaaaag gttatagata tgttggcagc
    28981 agtaataatt ttgcaaggat atttagattt taaaataaat tcataaaaga actataaaat
    29041 tgaatactta tgatatataa tataaataat aaaaataaaa ataaatttga ggtgaatgac
    29101 attatggaag aaaatataat aaatttaata gacgaaaatg gcgttgaaag ccaatttgaa
    29161 ataatattaa cattagaagc agaaggaaaa gagtatgcaa tattaatgcc tttagatgat
    29221 gaagaagctg aagaagcttt aatctttaga attgatgagg atgaagaagg tgaaatatta
    29281 atacctttgg aaagtgatga agagtatgaa actgttgtag ctgtgtatac tgctataatg
    29341 gaagaagaag gtttaaatta cgacgaagat gaatcaaatg gacttaacta gataagtaat
    29401 taagtttgta tataaaaatc agatatttat tatatttgct ttaattaaac cttattaatt
    29461 gtaaaagcat ttatagtata tatctgtttt tttgtttttt attaaaaata ccaaaaaatt
    29521 tatgaatttt ggtgaataat atatctttta tgggtatata tttatattat gagaataaat
    29581 taaatttatt taaatgtctt gacaaaaaat gaattatcaa ttacaatatt atttaataaa
    29641 gattatcaat tgaaaatagt aagggtgatg ttatggcaaa tacaatggat ttattaaaag
    29701 acaagttaaa agaaactggt tttaagatta cgccacaaag aagagcaata gttgaaatat
    29761 tgcttaaaca tgaccattca catctaagta gtgaggaaat ctatgattta gttagggttg
    29821 actgtcctga aataggctta gctactgtat atagaacaat gcagctattg gatgaaatag
    29881 gattaatatc aaaactaaac ttagacgatg gatgtataag atatgagatt agtctacata
    29941 aagaagactg tcataatcat catcatctta tttgtaaaaa ttgtggaaag ataatggaag
    30001 ctaaagaaga ccttttagac aatatagaaa aagagataca atcattgtac aaatttaaaa
    30061 tacttgatca tgatgttaaa ttttatggat tatgtgacga gtgtaatgga gtaagcgatt
    30121 cagaagaata aacttctatt gcttaatgtc gatggaagaa tagtatagaa cttttatatt
    30181 ctatgctatt cttccatttt ttattataaa ccatctacaa aatgcaaata tacagttttc
    30241 aagatgctta tagttttaat attgaaaata taattaatcc tataagtaca aaaatgaatg
    30301 atttttctat gaaattacta aatggtcctc caacagttaa aaaacctaaa gaaattttct
    30361 tttcgcttag cggataaaaa attggtattc cttgctttgt aaataaatct cctaaaaaca
    30421 tatgacttgc ataaccaatc gtaccataaa aagataaatt attaatatta gtgattaatt
    30481 ctatctgttt tagtaaaaaa tatactatta tagttgcaaa tatgctatga gaaaaacttc
    30541 tgtgctttaa ccagggaaaa attgacaaca ttagacaaaa aattgtaaaa tatatttcaa
    30601 cttctatgat gtataagcat atagctaata gtataaatat taatgataga aaaacttttc
    30661 ttagaaatgt gtgggttagt tttgcttcaa taattataat tgcaacaaat gtaattattg
    30721 cgcttaaata aaaattatca tttatattta ttgaaataaa gaaaataata atattaacag
    30781 catatataaa aattctatat atgtatttgg atacattgtt ttttagaatg aaatttgaga
    30841 ccatagaatt agatttatcc aaatcgggta gtacagcaaa agtagctgaa actaaaatat
    30901 caactaaaga tataggaatt ttaaatatta aagatgtttg gatagctgtt aagattccta
    30961 ttgcacaatg agttttacca cgcataaatc ctcctaaatt atccgatatt aaatcatata
    31021 atatttagag gatatcaaaa taaaataggt ttgtcaaaat aatacgttaa atgtatttta
    31081 aatatagctt aaaatatgat acgaattatg gtacaataag aataactggt agcgagtgcg
    31141 tgatttgata ttatttatga ttgtagaacg tgttaaaaaa ttaaatagac agaaggagat
    31201 gatgcaattg ttcaaaaaga acaccaacaa gataaaggta atggccttgg gtggacttaa
    31261 cgaagttgga aaaaatatga ctgttgttga gtataaagat gaaataattg ttatagatgc
    31321 tggacttagt tttccagagg atgaaatgtt aggagtagat atagttatac cagatataac
    31381 ttatttagta aaaaataggg ataaaataaa gggtatattt attacacatg gacatgaaga
    31441 ccatatagga gctcttccat atatattaaa gaaaataaat gtacctgtat atggggcaag
    31501 acttagtata ggtcttatac aagtaaaact taaagaacat aaaatgaata atgttaagtt
    31561 aaatgttata ggtcctagac aagttataaa gcttgataat atggaagtag agtttttgaa
    31621 aaataaccat agtataccag atgcttactc tattgcaata cacacagacc aaggtataat
    31681 ataccacaca ggagatttta agattgactt gactcctatt gatggagatg ttatggatat
    31741 gcatagaatc tgtgagttga gcaaaaaagg agttctttta atgctggcag atagtactaa
    31801 tgcagaaaaa ccaggattta ctatgtctga aaagactgtt ggggtaggtc ttgacgaatt
    31861 atttgcaaaa ggaaatggca gaagaattat agttgctacc tttgcatcca acatacacag
    31921 attacaacaa ataataaata ctgctgaaaa gtttaataga aaagttgcta tatcaggtcg
    31981 ctcaatggtc aatgtagtcg gagttgcaaa agaattagga tacctagata tttctgatga
    32041 catgcttata gatttaaatg atatatgtaa gtatgaagat agtgaattag tgataataac
    32101 aactggttca caaggtgaac ctatgtcagc tcttgctaga atggcttttt cagagcacaa
    32161 aaaagtagaa ataaagagtg gcgatttagt tataatatct gctcatccaa taccaggaaa
    32221 tgaaaaatta atatcaagag taatcaattt cttatttgaa aaaggagcag aagtagtata
    32281 cagtgatata gctgatatac acgtttctgg acatgcctgt caagaagaat taaaacttat
    32341 acatgcatta gttagaccaa agttttttat gccagctcat ggtgaatata gaatgttaaa
    32401 aagacatgct gaaatagctg aacagcttgg tatggataaa gaaaatattt ttgtcatgca
    32461 aacaggagat gttttagaat tagataaaaa ctctgctaag gtagcaaacc gtatacaaac
    32521 aggaaacata ttagttgatg gtctaggagt aggcgatgta ggtaatatag ttttaaggga
    32581 tagaaagcat ttatcagaag atggtcttat gatagttgta gttactattt ccaaggatga
    32641 gggtaaggtc ttagcaggtc cagatataat ttccagagga ttcgtatatg taagagagtc
    32701 agaagattta atggatggag caaaggatat aattaagaat gttctaaatg aatgtgaaga
    32761 gaaaaatatt aaagaatggg cttatttaaa gaataatatt aaagaaaacc taaaagaata
    32821 tttatatcaa aaaactaaac gaaatccaat gatacttcct atcataatgg aagtataata
    32881 taaaaaaact ataaatttga aaattagacc tcttgtaatt tttaaagtaa tatcaaaaat
    32941 ccaattgata ttatcttaag aattacaaga ggtcttttta atactcattt aaaaaaaata
    33001 tatattacat aaaataccaa ttataacaat cttttattag taaaaactac ttatatataa
    33061 attttactga taggaggatt cttatggatg atgtttcaag acaaaatgct ataaaagctt
    33121 taaaacaaac aaaaatggaa atagcaggag agtatggaat gaattatgaa gatgcttttg
    33181 aaataataga aaatgcgtct aataaaggtg ttttagaagg ttactttaaa aagcttgaaa
    33241 agaaaaaaaa tttaggtcaa ggtatatcta ggcatttaga ataaaaaaag ttaaatgtga
    33301 gaaaataagt ttaaataaac tttaagaggt gacatcgatg aaaaaattag ctagtactgc
    33361 tttggctata ttaattgcgc ttactccttt aagcttttct tttgcaaata ataaggaaaa
    33421 tgctgatgcc aaccaactaa atatatcttc aaaatcagca attttgatgg atgttggtag
    33481 tggacaaatt ttatatgaaa aggatgctca taaaaagctt cctcctgcta gtgtaactaa
    33541 ggtaatgact atgctactta tagtagaagc tttggattca ggcaagatta agcttgatga
    33601 tgaagttcaa gtaagtgaaa ctgcatctag tatgggtggt agtcaaatat tcctagagcc
    33661 aggagaaact caaaaggttg atacattatt aaaaggtata gctgttgctt ctgcaaatga
    33721 tgcttgtgtt gctatggctg aacacttagc tggaagtgtt gaaggatttg ttgatagaat
    33781 gaatgctaaa gcaaaagagt taaatatgaa tgatactcat tttgcaaata caaatggact
    33841 tccagttgca aaccactata catctgctca tgatatagct ttaatgtcta gagaactatt
    33901 aaaacacgaa atgataagta aatacttaac tacatggatg gataaggttg tagtagggaa
    33961 gaaacaagtt acagtaggtc ttgcaaatac taataaactt ataaagcatt atcaaggagc
    34021 aactggtgtt aaaactggtt ttactcaaga agcaaaatac tgtttatcag catctgcaaa
    34081 gagaggtaat actcatctag ttgctgcaac tttaggagca gagacttctc cagaaagatt
    34141 taatgatgcc tctagccttt taaactatgg atttgctaat tatgaaagtg ttaagttatg
    34201 tagtaaaggt gataatatag caacacttac attggataag gctgatgaaa acaaagttaa
    34261 attggttgct aaagaagatt taaatgctct tattaaaaaa ggaagctcta aagaatttga
    34321 gaagaaaatt gaaatagtaa aaaatcctaa gatgccaatt aaaaagggaa ctgttttagg
    34381 aaaaataaag atatgtaaag ataaaaaagt aataggcgaa gtggaattga taaatactaa
    34441 ggatataaat aaggcaagct atctacaaat gcttcaaaga ataattgata atatgatata
    34501 aataattatc agatgaaata taattataat acacaaagat atgattataa tacacataaa
    34561 aaataccctt atgtagttat ttgccatagg ggtattttta tttaccatat agaagtattt
    34621 tataatctta tgatttttat agaaatatag aaaagtttat gtatcttaaa atatcatttg
    34681 atttaatatc atatataggg ttgtttaaca attatctaag taaaggcata ctaccagtaa
    34741 gtttattcac tttcttttta ttcccataaa ttgctatccc aaaatactgt aactcatctt
    34801 ctggaacact agcaatcttt tgtgtaaatt cttcataaag attgcaactt tgtgctacat
    34861 ctgaaaaatc tacaacagtt aaatcgttaa attccaaagt atataatttt ttacgtaaat
    34921 cttttattat ttctttgttt ccttttaaaa taggtacagg aatgtcaata attcctaagt
    34981 ggctattacc tgttttgtca attacatctg gcccaacagt ttctggggca tgttttccta
    35041 gtgtaattcc cattatagct gctgtattgg atataattcc cattggtaaa ttttcgtcta
    35101 ttaccatgac acattttgaa tttttatttt ccatttttat ttctcctttt taccttattt
    35161 aaagttgttt gaatcatcat ttataaatat attttgatac tgctttggtg taagaccaat
    35221 aaaattctta aaaaagtttg taaagtgact ttggtctaca aatcctgttt gtatcgcagc
    35281 atctataggt tctacgcctt tttctaaaag ctttttagct ttgtttaccc gtatattttc
    35341 taggtatcta tatggtgtaa taccttttaa tttcgtaaaa ttacgaagta gagagtactt
    35401 attcatacct gctatagtgc ttaattcgtc aagtactata tgttcagcat aattattttc
    35461 tagataatca catactgctt gaatttctat atttgtattt tccaagttag attgcaaatt
    35521 tggctctgta tgttcttcaa ttaattgctc aattaggaag aaaaaaagct cttccttttt
    35581 aaaatccaat tcttcttcca tgattatata gtgtaattct tgtagtagag gtactagctc
    35641 actgcgaaat ataacaggtt gattaaattt tggtaaataa tttttacctg taatttcaaa
    35701 gacggttttt ttcattattt ctggcttaat attgatacat ctgtaatcaa gtactttatc
    35761 atctatttgt tcacaagtat gactgtcaaa agggttaaaa agtagcaaat ctccagtact
    35821 tgtggtatac tctttatttt tacaagataa atatctttga cctttttcta taaaaccaat
    35881 tacataatgt tcatgaaaat ggtttgggaa tttttgcatt atgcctttaa atctatatgc
    35941 ttcaattttt aattccctat caaagcatac tgtgcgttct tcttgtctca cttaggtaac
    36001 ctcctttcat gttatacaaa gtgtaacaca tattttttta tacttcttgt ataatattga
    36061 ctaagagaca ataatgtcaa ttcatgtcaa tataatatta cacttacagt aggtgtaatt
    36121 attatatttt cacaatgaat atgatataat aataaaagtt ataaaataaa aagcaaattt
    36181 taattttatg cctagaagtt aaaattatta taatgtaaaa taattttgat tataagctat
    36241 ttaattgtta taataatatt aaaaatttaa tttaggagat gtacattaat gttaagtatg
    36301 aatataggag aaatagtagc aagtttagtt ggtatagcta tggcaatatc aatacatgag
    36361 tttggccatg cttattcagc tcacttattg ggagatgata cagctaaagc ttatggtaga
    36421 atgacattaa atcctgtaag acatgttgat ccaataggtc ttttggctat gtttatcctt
    36481 aagatagggt gggcaaagcc agtaccagta aatccaaata attttaaaaa ctataagata
    36541 ggaaacctga tagtttcact tgcaggcgtt ttttgtaatg ttttgactgc tatactgtgt
    36601 gtaattatca ataagtatgt gcatatgtat gctataaata caatagctgg atatgtgctt
    36661 atatatagta tgggatttgc agcttttaac ttacttccga tacctccact tgatggatgg
    36721 ggagttatat ctacatttgt accatataaa tggaatgaat atttgtataa atttgaaagt
    36781 atgagttata taattttatt aattgcttta tttactggta tatatcaaat aatactatca
    36841 ccaatatata cagtgttgct aaaaatagta tatttatttg tttaatataa taaacagatt
    36901 aaagagggat tgatatgaag tataatatac aattacaagt ctatgaggga ccattagatt
    36961 tactttatga tttaataaca aagcataaaa tagatataaa ggatatatct ataatagata
    37021 taactaagca gtatctaaat tatttgaaaa tgctagataa aatggattta gagataacta
    37081 gtgaatttat aactatggca tcaaaacttt tagagataaa gtctaaatat ctgctttata
    37141 agcaaaaaga tgaagaagaa gacccaagaa tagaacttat ggaaaagtta gaagaatata
    37201 gaaagtttaa ggtagcatca caagatataa aagaaaatat aacttatgtt aatgagagat
    37261 tttatagaaa taaagaagag ataattattg atgacaatgt ggatttagaa gatatatcaa
    37321 ttgaagcaat aaaaaatata cttccataca tatttaaagt taaaacatca cagatagaaa
    37381 atgctaatga tgagaaacta gacaaaatag taaggaagaa gataatatct gtggaagaaa
    37441 agatattgta tataagagat attataaaag ataagattga agttactttt acaaatatta
    37501 taaaatcata tgaaaatgat gaaataatag ctactttttt atctatatta gagcttataa
    37561 aagaaaaaga aatagtagta gtacaagaca tattttttga tgatattcta ataagaaaaa
    37621 gttcggagtg ttaaaatgaa aagagaagat ataaagtata ttatagaatc tgttatgttt
    37681 gcatatgggg aaccaataag tataaaagaa ttaaactata taataaataa agaactttca
    37741 tcaaaagaaa tagagattat gttaaattta cttattgagg agtacagaga acaaaataga
    37801 ggtattcaaa taatcaagct agagaataag taccaaatgt gtacaaataa agactatgca
    37861 gaatatataa agaagattat tgaaccaaag aaaaagaaaa gtttgagcca agctacatta
    37921 gaaactctta ctataattgc ctacaaacaa ccaataacaa aggtagaaat agaggatata
    37981 agaggagtaa aatgtgataa ggtattacaa actttgtttg aaaatgaact tataagagaa
    38041 gctggtagat tgaataagat agggaaacca ataatttata aaacaacaga tgaattttta
    38101 aagttgttga atatagaaag tcttgaagaa ttgccgccta tagaaaatta tcaagaagtg
    38161 gcaacaaatg aataaaaata taaaatcaca ataatttagt atgtaatttt aaattttaaa
    38221 agatttaaaa tgctctaagt tgttgtgttt ttttgtataa atataaaatt ataattctct
    38281 taaaataaat atggataatt aagtataaat agtaattttt tgatgataat ataaacatgg
    38341 agcttaatga attatttaat tttaagtatt taataatagc tgtaattttt attataagtg
    38401 taactatgtt gattttaata tctcatataa acatcttaat aatagctgat ataaacaaca
    38461 aagatatttg tttaaagctt aatataaaat acatgtttaa tttaataaat ataaatagac
    38521 aactttatcc agctgaaaat agtaaaaata atgataaaaa agaggggatg aagaataata
    38581 tagattcaag tatattatta gctgatgacc ttttgagcat ttatagatta ttaaaaaaga
    38641 taaaaataca tgaactttat tcaaatatta attttggaac tggaaatatt ggcttaacat
    38701 cttctgtata tgtattgata aatactttgt atggaaattt atttaatatg attgatgcag
    38761 aaaaaatgta tttaaatgta aatccagatt ttacaaaaga ttatgtttta ggaaatataa
    38821 ggatacatat aaggccaaga ataaaagctt tatttaatat tataataatg attaataaaa
    38881 ttatgaataa aaataaagga aataaggaag gtgatagtaa tgagagcaac aggttcgata
    38941 caaagtctta tggaaacaac tcttgaaaca attaaaggtt ctatagatgc aaatactatt
    39001 ataggagacc ctataaaaac agatactaca gtggttgtac ctatatcaaa ggttacaatt
    39061 ggctttggta taggaggagg agaatactca aaaggatatg atgataaaga tagggaaatt
    39121 gaattaaaaa atgaaaaatc agatacgaat tttgctggag gtagcgcagg ggctatatct
    39181 gtacaaccag tagcatttgt agtagttgaa agtggagaga ctagaataat gagtttagac
    39241 agtaatatca atctagtgga taatatatta tctataactc ctagagtatt ggagaaaatt
    39301 caaaatatat cacaaagtaa taagaatcaa gataaaaaca atatgtaaga ataaaatatt
    39361 tttaaatatg tatatagttt taagtaaagt agtggggtta gtataaatcc cactattttg
    39421 ttgtgtactt taaacattta tatctaataa gattttagtt taaaacaatt taaatagata
    39481 ataaagttga tatatagtat aattataaaa agaaaagaag tattatatta tagatatata
    39541 aacgcatttg agatataaga gggagttata aatcattagt tttgaggtga atgttatgag
    39601 cgataaagaa ttatctattt tgttgttaga aagtatgaat aattttcata atttaataaa
    39661 gattattaat aacgaaagat ataaaaaaga taaggttctt acagaaagac agttctttgc
    39721 cttagtaaaa ataagaaaac atgataaaat agagcttaaa aatctaagta gagatttaca
    39781 tgtatctact tctagtctgt gtatactact taataaattg gttgagcaag agtatgtata
    39841 tagggaagaa gatagtagag atagacgaaa tactttttat ggaataacta aaaatggaga
    39901 aaagatattg gataatgaaa tactaaagtt tgtatctata ataagtgata aaatggattg
    39961 cttagatata gataataaag ataaattatt tacttctttg gaagagtcta aaaatataat
    40021 agaacaatta ttttaaaaag gagaatttat tatgaatata aagtattcta aagagatatt
    40081 aaaaagttta gaaaatgcta taacagtagt agctctattt gagggagaag atgtttctac
    40141 gacatttgat aaaataaata tgataagcag aaattttaat tctaaagaaa atagtataga
    40201 tactgtaaca ttggttgaaa ataacaactt ggtaaatgtt tgtcttgttg gttttggtaa
    40261 gagagagtta ttgaatagag aaaaaattag aatcataggt ggtaatttgt gtaaaaaatt
    40321 aaaaaatata ttgaaaaatg aagcatataa gagtagtgat gttaatgtac ttaatcttaa
    40381 tttaaatagt gatgaaatag gttcttttgt agaagggata ttacttggaa attataagtt
    40441 tgataagtat aagacaaaaa gtaaggattt tgaaagaaaa gaagttgata ctataactat
    40501 atttactgaa aaagaagttg agtgtcaaat agaaaaggct aaaatattag ctaattcaac
    40561 tataatagct agaaatctag ttaatgaacc atcaaacgta atatatccaa aaacattagc
    40621 aatagaaaca gttaaacttg gtgcagagtt cgggtttaat gttgatgttt atgaagaaga
    40681 aaaaataaag gcattgggaa tggatgcttt tttcgccgtt tcaagaggtt caatcaataa
    40741 accaagattc atagtaatga gatactttgg agataaagaa agtacagata tattaggtct
    40801 agtaggtaaa ggattgactt atgatactgg tggatattct ttaaaatcaa atgcttctat
    40861 gctagatatg aagacagata tggctggtgc tgcgagtgtt ataggtgcta tgtgtgctat
    40921 atctcaaagt aaattaaaga aaaatgttat agcagtagtg gctgcatgtg agaatgcttt
    40981 atcaggaggt tcatacaaac ctggagatat aattagttct atggcaaaga aaactattga
    41041 agttttaaat acggatgccg aaggtagact tacattagct gatgcaatat actacattat
    41101 aaacaatgaa aaagtaacaa aggtagttga tgtagctaca ttaactggtg ctgctttaac
    41161 attgttagga aatgttgcaa ctcctatagt aacaaataat gatgattttt attgtgaatt
    41221 agaaaaagct gccactttat caggagaaag ggtatggaag atgccaattt atgatgaatt
    41281 taaagatatg ataaaaggag aagaagcaga ccttaaaaac actggtggta aaaatgctgg
    41341 atgtataaca gcaggagctt ttattggtga atttgttggg aatactcctt ggatacatat
    41401 ggatatagcg gggacaagta catcatcaaa atcaattgga tacaaagcaa agggggctac
    41461 aggagaacct gttagaacat tatactattt ggcagaaatc taaaaaacaa ttataaaata
    41521 taatttataa agccacatgg atatttttgt aatttaagat tatctatgtg gctttatttt
    41581 ttatttaagt aaattattta ctctttttct ttttctcaag tataaaagta tctctattaa
    41641 ataaaagagc aggtatgtac ataatactag taacaaaaat aaacgtaaaa atagcagttg
    41701 tgctatgact taaaaaacca taatagtatt gtgagttggt aaatgtgttt agtaaaaata
    41761 tgaatgaaaa ataaataaaa catatagcta agttatctct aagtgcatat ctgttaactc
    41821 taaattttct aacatcaacc atatatatat ctgcataaat tatcaagcac ttagagaaga
    41881 taaatataaa atatattaag ctaggaaatt catagcccaa gtttttagaa aaaatgagtt
    41941 ctccaactga acaaactaaa ctccaagaaa aaaatatatt aaaaagatga tactgcttaa
    42001 aaattagtat ggctatacac agatatatac agatataatt gattccaatt ggtaaagagt
    42061 ttagagtact ataattacct gaagaaataa gtaataattg ctctagagcc ataattatta
    42121 caagtaatgt acaaattatc ttctcaactg tatagctata aggtaaaata tttttggtta
    42181 gttttggaca atagtataaa aataatccaa atataaagag acttacaaat tgttcactag
    42241 aaaaaagaaa aattttaaac atataacatt ctctcctata ataaatttaa tatgtatcta
    42301 tataaatata ttcattatat ctcaatttaa tatataaaaa agataataat agttagactt
    42361 tttatatgaa ttttaatagg taaaatatcc tattgttttg tagatatatc ctaattatgt
    42421 caaaaaataa aaaaattttt atttattaga gtttttggaa ataataataa cagatattat
    42481 aattaattaa cagtttttgt aagtatttga caatagagag ggtgtaacaa atgggaataa
    42541 tagagtcagc atcaaaattg gctgagatgg ttcatttatt ggctgttgaa aaggggataa
    42601 ctgatataga agcatgggat gaagctgtga aagaatacag caaaatttat gaagaaagaa
    42661 gaaatgaata gaatgataaa aaatgaaaac ttgatgataa aaaataactt tatttaaaga
    42721 aattcaattt ttatagaaat attaaaaata atataaataa aaagatggta tttcaaatgt
    42781 aagtaaaaaa tcattttggg ataccatcct tattatttat tttaataata tataagtaat
    42841 aaatcttact tatccatatt ttttatgtaa cctctttttt ctagcttttt tatatgctcc
    42901 ttacgtattt catcaagatt aataccatat tgttcttcta gcttaaacat catagtaaca
    42961 catgtctgag ctacatccat tagttcctta gcagttttct ttataatatc aacttcatct
    43021 aaatcattat tttctccact tagatttctg aatttaccta tacattcagc taattcacct
    43081 tgttcttcac ccattttgat aaatgtagat tctagtgttg ggtctaaatt attaagctct
    43141 ggtaaagata tagtttttag tttcataaaa gctcctttca agttattcgt atttatacta
    43201 aaacatcata acaaaaataa tactaaaaaa aaactttaaa ttcaacataa aaacttacat
    43261 atataataaa aatcgtgaaa taaatctata tttgtcttaa tacagcctca tataaaactt
    43321 ctccaatagg tttatttatt acaagagaag ctgacttatc atagactgta tttgctttat
    43381 taataagagc aatataatca cctttgtaat aatctataaa acttgctgct gggtacacag
    43441 ctaatgatgt acctcctata atcaataaat cagcattact tatagcagaa attgttttag
    43501 taatgacatc actgtcaaga gcttcctcat aaagtactac atctggtttt actatagaac
    43561 cacagttgtc acaataagga atattacctc ccagatttaa catagattct aagtcaaaaa
    43621 acttaccaca tttagtacaa taatttctat gtacagaacc atgaagttct agcacatttt
    43681 tacttccagc catttgatga agtccatcaa tattttgagt tatgacagct ttaagcttac
    43741 ccatttcctc gagttttgct aaagctatat gagcattgtt gggttttgca ttaggatata
    43801 ttaatttatc cttataaaat tcaaaaaatt cttctggata tctaacaaaa aaagtatgtg
    43861 aaactaattg ttcagcagta aattgtttat tgagtttttg gctaaataat ccagtagaac
    43921 ttctaaagtc tggaatatta gattcagttg aaacacctgc tccaccaaaa aatacaatat
    43981 tattgtgatt agctattaag tcttttaagc tatttgcatc catagttaca cctccaaatt
    44041 attatatata aattgtacta catattaggt cttttatgtt ttattaattt aaataaatat
    44101 gtagtttaat aagttaaata aagggaatat aaataaaatg tatacagagt ataaatagac
    44161 aatatttact aaaataacaa gttgtcgtat aattatatta aaattgtttt agtgtataag
    44221 aagggcgggg gaagtacgtg aagaaaaaag cagctttagc aacattggct atgttaccct
    44281 taggtgtggt aaatgcacat gctgatggag atataggtat agtgactata aattatttaa
    44341 atgtaagaaa tgagccaact gccgaaagta gcatagcctt tgttgctaaa aaagatgata
    44401 aagttttgat taaagactct tctaatggat ggtataaaat aaaagctgaa tctggacaag
    44461 aaggttgggc ttcatcaaaa tatatagcaa aatcaaatag tgactcttta agaacgtcta
    44521 caaataaaga aaaacaagtt atttcaaata gtttaaatat gagaaatgga gcaggtacaa
    44581 gttacagagt aataactgta ctaaaaaaag gtcaaaaagt agaagtaata tcagagagta
    44641 atggatggtc taaaatcaaa tatgatggaa gactaggata tgtatctagc tcttatttag
    44701 gagacgtttc aaattcaact aataaatcaa aaactaaaca agtgaataca acttcactaa
    44761 atgtaaggag tggaccaaat acaagttatg gtttgttagg caagttgcca aaaggaagta
    44821 aagtagaagt aatatcagaa agtaatggat ggtccaaaat aaagtataat ggaaaagatg
    44881 cctatatatc tagtatgtac ttatcggatg taagtcaaag taattcagac aattctagtc
    44941 aaagcaatga taaaaagaat actgataagg ttgtaaatac agcttcttta aatgtaagaa
    45001 gtggaccagg ttctacatat agtaagttgg gaaaagttta taaaggaagt aaagtaactg
    45061 tactatcaga aagtagtgga tgggctaaga ttaattttaa caataaagaa gcatttgtag
    45121 taggcaatta tttatctact tcagcagata cttcaaataa taactcaaat agtaactctg
    45181 ataacagttc taatagtaat ggcaataatt cttcatcatc aggtcaagta aatggtatgt
    45241 caggtataag tggggctaaa attgattata aatctttgag ttatacttta gaatctcata
    45301 taagtaaaca agttgagaaa gcagcatcag gaggaaatgt gatagctcca agtaatagga
    45361 aaagcactcc aagtcctgaa tttagtactt tttcagctca aagaacaagc tcatttgtaa
    45421 atgcaagttc aagtgatata gaatattatt taaatcctaa aaattttaca aatactacta
    45481 aaggtatgat gcagttttta aagattaaca gttatagaga tggtatttca gaatcaagtc
    45541 ttaactcgta tcttaatggt ttatcttcta gtgtatttaa aaaccaggga gcagccttta
    45601 taaatgctgc caagaagtat aatatagatg ttgtatatct agtatctcat gctatgtggg
    45661 aaactgctta tggtaagtct acacttgccc aaggtcaaac attaacatct tataagggac
    45721 aacctcttag taagccagtt aaagtataca atttttttgg tataggagca atagataaaa
    45781 gtgctaatgt ttcaggtgca gaagcagcgt attccaatgg ctggactagt gtagaagcta
    45841 caatagatgg ctctgcaaag tggatatcac aaaattacgt aaatagttct aagtacaatc
    45901 agaatactat ctacaagatg aagtggaatt atgattatac atggcatcag tatgcaactg
    45961 atgtaaactg ggctaatgga atttctggaa ttatggaaaa tttaattggt ctttatggag
    46021 gaggaagtag tttggttttt gaagttcctc aatataagta atacataaat aaaaaatata
    46081 gactatgggt agttttcatt ttatttaaat tatctatagt ctttttgtat ataatttata
    46141 atctgtaaat ttaatgttaa caaaactttt atgttataat attaattcta agtaaatata
    46201 agtgagtaat aggtagaaat agataaaaag tggtaataat atatataaag ataattttga
    46261 gaaaggagga tatatatgga aagtattaag gaatatttgg ataagttaga aattaataat
    46321 agtggtcttg gaaagcaact taaagaagtt tatataaata gagtagttta ttttaaggaa
    46381 gataagatag tttattttta tctaacttct aaagatattg tttctcatga acttttagat
    46441 aaatttaaag aagaattgat gtataaactc gattatttta aagatatgag gatgaagata
    46501 agatttactg gtcttgaaag aaaatccaat aaagatgtta taaaaaaata ttggaataat
    46561 atattgtata tattaaagta tctttgtcca tctattgcag ggtggtataa acaagtagaa
    46621 tttctttgtt tagaagaaga attaaaaata aaacttccaa aaggtatatt ttatgagcga
    46681 ttaatgaaaa aaaatgtaac ttatgtactt aaaaccgtgc ttagcgaaga gttgggatta
    46741 gatttaaata taacaataga aaaagctgtt gatgaaaagg taaataaaga aagactcata
    46801 agaatcaatg atagagaaat ggaagaaaaa attagggctt tagaaattgg aaaagttaat
    46861 aactgtgaag aaaatgaaga ggaaagctat gtcattaagt ctgatgtaga tgaaaattta
    46921 atctatggag ataatgcaaa tgctatgatt gaaaatatag ttgaattaaa tgcatcttct
    46981 ggaacagttg cagttgttgg agatatattt gatgttgaca ctaaagaact taaaaacgga
    47041 aaaatactta tgatagcttc aattacagat tatactagct caataagctg taaacttttt
    47101 ttaacagata caaataagga tggagtactt gaaaatgtta aaaagggagc atacttaaaa
    47161 atcaagggtg acatagttta tgatacatat caaagagaaa ttagtatgat gattagtggg
    47221 ataagaaaag aaactagaat agagagagaa gataaatcag aggaaaaaag ggtagaactc
    47281 catgcacata cacaaatgtc ttctatggat gctatttgtt ctgttaaaaa gcttgtagag
    47341 cgtgcagcca aatggggtca ttctgctatt gctataacag accatggtgt tgtacaagga
    47401 tttccagatg ctatgaatgc aggtaagtca aataatataa aaatacttta tggagtagaa
    47461 gggtacttgg ttgaagatga ttctctcatt atagaggatg caaatgataa agaactttcg
    47521 cagacatttg ttgtatttga catagagaca actggttttt ctaatacaaa tgataaaata
    47581 actgagattg gtgctgtaaa aatagaaaac tttaagattg tagatagatt tagtgagtta
    47641 ataaatcctg aaaaagatat ttcctataag atacaggaat tgacaggaat aactaatgaa
    47701 ttaattaaag acaagccaac cattgaagaa attcttccta agtttatgga atttgttgga
    47761 gatagtgtat tagtagcaca taatgcagag tttgataccg gatttatatc gcaaaaatgt
    47821 agggaacaag gcttgttata taataacaaa aaagtagata cacttatgtt agcaagagta
    47881 atgttgccaa acttaaaaag acatagatta aatgtcgttg caaaagaact tggtattcct
    47941 cttttaaatc accatagagc agtggatgat gctgaggcta cagcacttat atttaataag
    48001 tttttgcaga tgcttacaga aaaaggtgca aaaactctaa gtgatgtaaa caatatactt
    48061 ggaaagattg attacacaaa gcttagcaca aatcatataa ccttgatagc aaaaaattct
    48121 ataggtataa aaaatttata taaaataatt tcagatgcac atgtaaatca tttttttaga
    48181 gcaccaagaa tccttagaag tgtattaaat gaatataaag aaggattaat aattggttcg
    48241 gcttgtgaag ctggggtggt ttttcaagct gtaaagaaaa acgtgtctga tgaggaaatg
    48301 aaaaaaataa tagatttata cgattatatt gaagtaatgc ctatagataa taatagattt
    48361 atgattgata aaggagaagt aaaggatgaa gaagagttaa gggagttgaa taggaaatta
    48421 attgatacag ccaaaaaatt tgacaaaatt ccagtagcta ctggggatgt tcatttttta
    48481 gacaaacatg aagctgtctt aagaaaagtt cttaaatatt ctcaaggttt taaagtagat
    48541 gaagaagaaa cttatttaca ttttagaaca acagatgaaa tgttggaaga gtttagttat
    48601 cttggagaag aattggcata tgaagttgta gttgaaaata gtaatctgat tgccgatatg
    48661 gttgaagata taaaacctat accagatgat acttatcctc caattataga gggctcagat
    48721 gtggagttaa gagaaatgtg ttacaaaaaa gccaaacgaa tctatggaga cccaatacca
    48781 gaaatagttc aaaaaagact ggatagagaa ttaaattcaa taataagcaa tgggtatgca
    48841 gttatgtata ttatagctca aaaactggtt gcaaaatctc tttcagatgg atatttagtt
    48901 ggttcaagag gctcagttgg ctcatctttt gcagctacta tgagtgatat aacagaagtt
    48961 aatcctcttc cagcacatta tatttgtgaa aacgaagact gtaaatattc attcttttat
    49021 gaaataggtg aatggggctc aggtgttgat ttaccagaca aggattgtcc aaagtgtgga
    49081 agaaaacttg ctaaaaacgg tcatgatatt ccatttgagg ttttcttagg ttttgaaggt
    49141 gataaggaac cagatataga cttaaatttc tcaggaaatt atcagccaac aattcataaa
    49201 tacacagaag aactatttgg agaggggtat gtatataggg ctgggactat aggtactgta
    49261 gcagaaaaaa cagcttttgg atacgcaaga aaatatgtgg aagaaaataa tataagtgta
    49321 ccaaatgcag aagtacttag gctttcaaat ggatgtactg gagtaaaaag aacctcagga
    49381 caacatcctg gtggagttat ggttatacca gactataaag atgtatacga ttttacacct
    49441 atacagtatc cagcaaatga tacttcttgt ggtgttataa ctactcactt tgattatcat
    49501 tcaataagtg gtagaatact taaacttgat atacttggac acgacggtcc taccattata
    49561 aggatgcttg aagatatgac tggaataaat ataacagaaa ttcctttaga tgataaagag
    49621 actatgtctc tatttacatc tacagaagca ttaggtgtta caccagaaga aataaactgt
    49681 cctataggtt gccttgctgt accagagttt ggaactaagt ttgtacgaca gatgttactt
    49741 gacaccaaac ccactacatt tgcagaactt gtgcgtatat ctggtctctc tcatgggaca
    49801 gatgtttggg taaataatgc acaagactta gttagagaag atatagttgg attaaaagat
    49861 gttatatcta cacgagatga cataatgaac tatttaatat ttaaaggatt acctcccaaa
    49921 atgagtttta caataatgga gagcgtaaga aaaggtaaag gtctaaaacc agaacacatt
    49981 gaagaaatga aaaaaaataa tgttccagaa tggtatatag gctcatgtaa aaagattaag
    50041 tacatgttcc caaaagcaca tgctgttgct tatgtaatga catcatttag aattgcatat
    50101 tgtaaagttc actatccaga agcattttat gcgacttatt ttacgacaaa agttgaggat
    50161 tttgatgcag atttaattgt taaaggatta gatgctataa aatcaaaaat aaatgaaatt
    50221 gagtcactgg gaaatgatgc aaccacaaaa gaaaaaggta tgttgaccgt tttagaagtt
    50281 gctcttgaaa tgtatgctag aggaataaaa ttattaccag ttgatatata taaatcagat
    50341 gcaactgagt ttatagttgt aggagaaaaa acattacttc caccaatggc agcaatacaa
    50401 gggcttggag gaaatgcggc tataaacatc caaaatgaaa gaaaaaatgg tgaatttata
    50461 tcaaaagaag atttgagaaa gagaacaaaa atatcaaaaa cggtaataga aactcttact
    50521 aatcatggtt cacttgagaa tatgagtgag agaaatcaat tgtcattgtt ttaagttagc
    50581 ccaaaaagtt gcaaataaaa gaattttatg atatcatagt atagaaaata gtatactttg
    50641 cagaaactaa gagtgagaca gctgttctca ctcttttatt ttaaatatat tattaaaaag
    50701 ttggtttatt tttattaaat atattttatt taagattata taaactaatc atttacaatt
    50761 gaataggagg aactttaatg aaaaaaaatt tagaagctac aattgaggag attgtaacta
    50821 aaataacgga tgaacatgga tttgaaatgg ttgatgttga atatgtaaaa gaagcaggag
    50881 aatactactt aagagtatac atagataaag aagaaggaat atctttaaat gaatgtgaat
    50941 tagttagtag agaattaagt ccaatactag atgaaaaaga ccctataaaa gaaaattact
    51001 ttttagaggt atcttctcca ggacttgata gagcattaaa aaaagacaga gattttgtta
    51061 gatatcaagg tagagatgta gatttaaaat tatataaacc attaaatgga tgtaagcaat
    51121 ttgaaggtga acttgtagga ttaacagaag ataataatat aaaaatcatt gcaaatggta
    51181 aggaaatgga atttaataga aaagatgttg ctattgtcag attagcaata aagttttagt
    51241 ggtatattaa atagggagga tataaaaaat gaatcatgaa tttatggaag cattagatga
    51301 attagtagtt gacagaggta tagataaaga aatacttata gatactatag aacaagctct
    51361 tttaactgca tacaagaaaa actttggttc agcacaaaat gttagagttg aatttgatag
    51421 agacaaggga gatataaaag tattttctca aagagttgtt gttgatgaat cagatttata
    51481 tgatactttc ttagaaatag agttagcgga tgctagagag ataaacccta attatgaatt
    51541 aggtgatatt atagaacatg aagttacacc taaaaacttt ggaagaattg cagctcaaac
    51601 agcaaagcaa gtagttgttc aaagaataag ggaagctgag agagaaatag tgtataatga
    51661 atttatagaa aaagaaaatg aaatagttac aggagaggtt gctagagcaa ataaaaatgt
    51721 tgtttatgta aatcttggaa gaatagaagg tataatgact caaagtgaac aaataccatt
    51781 tgagaattat aaagcaggtc aaaaaataaa attctatata cttgaagtta aaaagactaa
    51841 caaaggacct caaatagttg tatcaagaag tcatccgggt ctagtaaaga gattgtttga
    51901 agaagaagtt cctgaaatat atgaaggaat agttcaaata aaatctgtag caagagaagc
    51961 agggtcaaga actaaaatgg cagtaaaatc tatagatgaa aaaatagacc caattggagc
    52021 ttgtgttgga ccaaaaggac ttagagtaaa aaatatagtg gatgaacttg gcgatgagaa
    52081 aatagatata ataaaatata gtgaagaccc agcagagttt atatcagcag cacttagccc
    52141 atcaaaagtt gttagagtag atatagatga agatgaaaag tctgccttag taatcgttcc
    52201 agattatcag ttatcgcttg ctataggtaa agaaggtcaa aatgcaagac tagcagcaaa
    52261 attgactaac tggaaaatag atattaagag cgaatctcaa gcagaacaag aaatgttaaa
    52321 tcttgaaaat tccaaagaaa tagaagctga ggatgttgaa gctgaattta tcgaccaaga
    52381 agagttaggt acttcagagg ataattttag tgaagaagag taaggaggga tgattttgaa
    52441 aaaagtaaaa aaagtgcctc aaagaaaatg catagcatgt caagatagag actctaaaaa
    52501 agagcttata agaatagtta aaaataaaga aggaaaaata tttttagacc caacaggaag
    52561 agccaatgga agaggagcat atgtatgtaa aagctctgaa tgtctaaaaa aagctataaa
    52621 gagtaaagca ttaaataaag cttttaaaat agatgttcca gatgaagtct atgataatct
    52681 acttatggag ttagaagaat atgaaaaata ataaagaaaa agtactttcg ttcttagggc
    52741 tcgcaactcg tgcagggaaa atagtgtctg gtgatgattc aactttgctt gaccttaaaa
    52801 aaggaaaagt aaatttgatt ttaatcgcag aagatgcatc aaataatact aaaaaacttt
    52861 ttaaagataa atcaactttt agaaatattc catatctatt tttttcaaca aaagaggaaa
    52921 taggatttgc aataggaaaa tctccaagag cagttgtagg aataaaagat gaaaattttt
    52981 ctaaaaagat aattgaacta atagaaattt aaaataaaat agggggtgat cttgtgtcaa
    53041 aaacaagagt ataccaaata gcagaagaat taaatatatc aaatgaagag cttataaata
    53101 agttagctga attagatata aatgtaactg acaaagattc agtattagaa ggtgaagagt
    53161 tagaattagc acttgaaatg ttaggtgaag atttatctca agaaaatgga aatgttatag
    53221 aaatagatgg aaagttgaca gtacaagtat tagcaacgaa attagataaa tctccatcag
    53281 aaataattat gaagcttatg aaaatgggaa ctatggcaac aataaatcaa gagataagtt
    53341 ttgagattgc tgctttggct gccaaagact atggatttga attaacagta gctgaaagtg
    53401 atgatacaga agctttagaa atagaagctt taatggaaat tgaagaagat aaagaagagg
    53461 atttaaaacc tagaccacca gttgttacag ttatgggaca tgttgaccat ggtaagacat
    53521 ctttactaga tgcaataaga aaaactgatg tgatttcagg tgaagctgga ggaataactc
    53581 agcatatagg tgcttcagaa gttaaaatca atggacacaa aatagtattt ttagatactc
    53641 caggacatga ggctttcaca tcaatgagag caagaggagc acaagttaca gatatagcaa
    53701 tattagtagt tgcagcagat gatggtataa tgcctcaaac agttgaagct ataaaccatg
    53761 ctaaagcagc aggtgtacct ttaatagttg ctattaataa aatagataaa ccaggtgcaa
    53821 acccagataa ggttaaacag gaattagcag accaaggatt attagttgaa gactggggtg
    53881 gagaagtaat agcagttcca gtatcagcta agaaaaaaga aggaatagat acacttttag
    53941 aaatggtatt attggttgct gaaatggaag agttaagagc taatccaaat aaaagagcag
    54001 taggaactgt tatagaagct gagcttgata aaggaagagg gccagttgca acagtacttg
    54061 ttcaaggtgg tactttaaca gtaggtgacc caatcgttgc aggtgttgca tgtggtaaag
    54121 ttagagcaat gataaatgca aaaggtaaga gagtaaaaac agcaggacca tctacagcag
    54181 ttgagatatt aggtctatca gaagttccac aaggaggaga ccaatttgtc gaagttccaa
    54241 ctgataagat tgctagaagt gtagcagcaa gaagacaaca aatagttaga gatgaaatgt
    54301 taaaatcaac tcaaagatta tcactagatg ctctatttag tcaaatgagt gaaggttcta
    54361 taaaagacct taatatagtt ataaaagcag atgtacaagg ttcagtacag gcagttaaac
    54421 aatctttaga aaaattatca aatgaagaag ttcaagttaa agtaatacat ggtggtgttg
    54481 gagctgtaac agaatcagac atattacttg cagcagcttc taacgcaata ataataggat
    54541 tcaatgtaag accagttcca ggtgcagaat ctctaggaga aaaagaaaat gttgatataa
    54601 gaacatatac tataatatac aaggcaatag aagatataca agcggctatg actggtatgt
    54661 tagaccctga atatgttgat gaagaaacag gaaaagctga aataagagaa atatataaaa
    54721 tatctggtgt tggaacagta gctggatgtt atgtgactaa tggtaagata tttagaaatt
    54781 gtaaagtaag attagttaga gatagcataa taatacatga aggtgagctt gcagcactta
    54841 agagatttaa agatgatgta aaagaagtta attctggata cgaatgtggt atgagttttg
    54901 taaattataa cgacataaaa gaaggcgata tagtagaagc ttatataact aaagaagtag
    54961 aaagaaaatt ataaattcgt atcaaagaaa atcagttagt aaagaaggtc gatggtatgg
    55021 catcatataa tagaacaaga aggatagcag aagaaataag aaaagtcgta agtactatgc
    55081 ttataaatgg agtaaaagac cctagaataa catctatggt gagtgtaact gatgtagaag
    55141 ttacaaatga cctaagatat gcttatgtat atgtaagtat tctaggtgga gatgaagaat
    55201 ccacactaac aggtcttaaa agtgctggag gatatataag aagagaagta ggaaaaaata
    55261 taaaacttag atatattcct gagatagtat ttaaacttga tgattcaata gaaaaaggaa
    55321 tgtatatgga taaccttata aaaagagtta atgaaaaaaa tgctcaacaa aatgaggatg
    55381 aaaattatga tgaataatat ggatagtatt ataaactata tttatgaggg tgactatttt
    55441 atagttacct ctcatatcag tccagatgga gacaatgttg gttctacact ttcaatgtat
    55501 tatacattga agaatttagg aaaaaatgta tattatgtac ttgatgatga agctccatta
    55561 aatttaaggt ttttggttga aggtgtaaaa atctataagt ctaatgaatt taatatgaag
    55621 aactattctt taattgcact tgattgtggg gataagatga gaatatgtgt gagtgatgaa
    55681 atcaaaaata atgcatcaaa attaatctgt attgaccatc atgctagtaa tgattcatat
    55741 ggagatttaa attatgtaga tattgatgca tcttctacat gtgaactagt ttataattta
    55801 ttggttagat ttcagcaaac aaaagatatt aatattataa atgaagatat agcaacatgt
    55861 ttatatacag gtcttgtaac tgatactgga aacttttcgt attcaaatgt acatgcaagt
    55921 agttttgaaa tggcaaaaaa tttacttgtt ttaggtgcac aaaaaaatac tataatacaa
    55981 aatatatatc aaagcaattc ttctgattat tataaattat taggagaagc tctaaaaggt
    56041 ttggagatat ttgattcaaa ggtatctagt atagttttaa ctcaagacat gatgaataga
    56101 aataatatta gctttaatga tgttgatgga ataacaacat atacaagaga tataaaaggt
    56161 atagaagttg gaattttatt taaagagaaa aaacaaaatg aaattaaagt gagttttagg
    56221 tcaaaaaatt atgttgatgt aagtgaaata gccaagttat ttggcggtgg tggtcatgta
    56281 agggctgctg gatgtactat tagagatagt attgataatg caaagaaaat ggtactagag
    56341 gcagtgttaa aatcaattta aggtgacagt aaaatgaata agattataag tatattgaaa
    56401 cccacaggta tgacatctca tgatgttgta agtagagtga gaaagatttt aaatataaaa
    56461 aaagttggtc atacaggtac tcttgaccca gatgcttcag gtgttttacc aatctgtata
    56521 gggaaagcta caaaagtatg tgaagttatt ttaaacaaag ataaatcgta tatatgtgag
    56581 cttactttag gtataagtac agatacttat gatgcttcag gtgaaatttt aaaaaaagtt
    56641 gatgatttta aatttagtaa tgaagacata gaaagagctt ttgatacaca aagaggagag
    56701 ataaatcaac ttcctccaat ttattcagct ttaaaggtaa atggaaagag aatgtgtgat
    56761 ttagtaagaa gtggtagaca atctgaaatt actttaaaaa caagaagagt aaatataaaa
    56821 gacataaaaa tactaagtat aaaaggtaat aaagtaatgt tttatgttga gtgttctaaa
    56881 gggacttatg tgagaagtat ttgccatgat ataggagaat atctgggttg tggagctcat
    56941 atgtcgtttt tgaatagaac atcttctggt aaatttgact tagataattc aataacatta
    57001 gaagaattag aattatttta tgaaaataaa actttagaca aatacttata tgatatagat
    57061 tatgtccttg attcgtttaa ttatgttgta ttaaacccta atgctataaa atattatagt
    57121 aatggtggct caatagatga taaaaggttt ttaaaaaata atttcgataa agatgatgaa
    57181 gttgtaagag tatacagtac agataatttc ttaggattag gaaagttatc aaaacacaat
    57241 aatacaataa gtgttaaaag tgataagatg ttcatataac caatgtattt aaaaaaacaa
    57301 caaaagagat agtactataa taacttctat agtctatctc ttttacttat gctataatag
    57361 tttgtgaata agttaagagt aaattatatt ttagcgggga acatttatta tggtgattat
    57421 aaaatctata aaagaaatag caaacataaa agaaagtgtc attaccatag gaaattttga
    57481 tggtgtacac aaaggacatc aagttcttat aggaaaaaca gttgaatatg caaaaaaaga
    57541 aaatatacag agtattgtat ttacatttgc aaatcatcct gtaaattact ttagaccaaa
    57601 ctcaacaaaa aatattataa gcaatgatga taaaataaaa ttattagaag atttgggaat
    57661 agatatagtt gtaatcatac catttgatga gtatatgact aaaatacctg caaaggattt
    57721 cgtagatgag atactagtaa aaaaattaaa agctaaaaag atagtaattg gacatgactt
    57781 tacatttgca agggcaaaag aaggcaatgt taatctatta aaaagcttag aacatgaatt
    57841 tggttttgag gtagaagtaa taaaacccat caaaatcaat gatgtaagag tgagtagtac
    57901 ttatattaga agtttagtat cccagggtga tatggctaat gtcaaggaat atttgggtag
    57961 aaattacaag ttagaaggtt gtgttataca ttctaaacac cttggaagaa ctataggatt
    58021 cccaacggca aatattgacc ttaagaataa tatgctcgtt ccaaagagag gtatttatgc
    58081 ttctattgta catattggag atgagactta ttttggtgct acaaatgtag gctataaccc
    58141 aacagttaat ggaaaaactt tgtctattga aacaaatatt ttagagtttg atagagatat
    58201 ttatggggaa aatataattg ttgaattttt ggaaagaata agagatgaaa gaaagtttaa
    58261 ttcaatagat gacttaaaaa atcaattgta taatgataca aattatgtgt atgaaaacta
    58321 tgtttgcaaa aacaagtaat gtatgataaa atgattaagg aaaataacca ttactcggca
    58381 tttgaatact ccaatcaatg cttagtaata ggcgtttcta aaaaaatacg gaggtaatct
    58441 aaatgataaa caaatcagaa ataataaaag aatatggaag agctgaaggg gatactggtt
    58501 ctccagaagt acaaatagct ttattaacag ctagaataaa cgagttaaat ggacatttaa
    58561 aaactcataa gaaagaccac cattcaagaa gaggactatt aaaaatggtt ggtagaagaa
    58621 gaaacttatt agcttactta aaggaaaaag atcttgaagg atatagagca ttaatagcta
    58681 aattaggatt aagaaagtaa tttcattctt tataaaaaag caggtatagt gtatacctgc
    58741 ttttttatag ttaattcatt ataaagtaaa atagttaata ataaaagtag tttatatgtt
    58801 ataaaaaatt ataaaatgaa taatattggg taagaatatt aaaatagtat acaaatacat
    58861 aatcaattta aaaggaaaga caggataaat atagaaattt tataacagga taattagttg
    58921 gaataaggag gatattattt tgaaaataaa gttagtatgc gatagtttgt gcgatattcc
    58981 agatgaaata tcagaaaaag attatataga gatagttcca cttacagtta tttttaatga
    59041 tagggaatat atagaaggag tagatataaa gaaagaagag ttttataaaa aagtaaaaga
    59101 aatcaagcaa atacctaaaa cttcacaagc tacatatatg gagtttaaag aagtgtttga
    59161 taagttcata acagaaggtt atcatataat ctgtatgaca ggggctgcaa acgcatcagg
    59221 aacttttcaa agtgctatga tagctaaaaa tgatgtaaat gaaaatgaaa aaatacatat
    59281 atttgatact agaaatttat ctctaggtag tggacaatat gttataaagg catgtgaact
    59341 tcttgaagaa ggactgggat ttgaagaaat tatagatgaa ttagaaaata ctcgcagtag
    59401 tgtaagatta ctttttgcac catatacact tgatttttta aagcagagtg gaagagttcc
    59461 agttgcaact gctttgatag gaaatatgtt aaatataaag cctatatttt tctttgataa
    59521 tggggaagct aagttggtaa ataaggttag aggaataaag aatatagcaa gtaaactggt
    59581 cgatataatt ttagaaatga atgaagggtc tttagaagga aaaatcgtca caataggttg
    59641 tggagataat ttacacgatt gtgaaatatt aaaagatgaa gtaaataaaa gaataaaagc
    59701 aagaagagta ttatttactc gaggaggagt ttctatttgc tctcatacag ggccagatat
    59761 attggctata agttgttcta attagtagta atataaggtt tttgcatata tatgtgaaga
    59821 taattttata ttgttaattt atagtatttt tgataatata gtaaatagag tgatatacgt
    59881 gttttttaat aagaggagga caagcattaa tgtttgaaca taaaatattt aaaatggatt
    59941 ttgcaggaag agaactttct gtagaaatag gaaagatttg tgaaatggct agtggtagtt
    60001 gtatagttcg atacagtgac agtatggtaa tggtaaatac aactaaatca gccaaaccta
    60061 gagacggaat agactttttt cctttaagtg tggattatga agaaaaatta tactctgtag
    60121 gtaagatacc tggaggtttt ttaaagagag aagggaagcc ttcagaaaaa gctatactta
    60181 catcaagatt gatagataga ccaataagac ctttattccc aaaaggattt agaaatgatg
    60241 ttcaggtagt tgcaacagtt ctatcagtag accaagattg tacaccagat atagtagcaa
    60301 tgataggttc ttcaatagcc ctttctatat cagacatacc atttaatgga ccaacaggtt
    60361 cagtatgtgt tggccttgta gatggtgcat ttgttgtaaa tccaaacgca gagcaaagag
    60421 aaaaaagttc aatgcatcta gttgtttcag gtacaaagga agcaataatg atggttgaag
    60481 ccggagctga tgaagttcca gatgaggtaa tgcttgatgc tattttattt gctcaccaag
    60541 aaataaaaaa aatagttgag tttatagaag gtatagttgc agaagttgga aaagaaaaaa
    60601 tgcctgttga attataccat gcaggagaag aaataactca attggttcgc gaatttgcaa
    60661 ctgataagat gaaaaaagca gttcagactt ttgaaaagtt agagagaatg gaaaatatgg
    60721 atagagttaa agaagaaact ttagctcact ttgaagaaac tttagaagat tttgaagatt
    60781 ttgttggaga tatagaagaa gtattacaag atataataaa agaagaagta agaaaactta
    60841 tagtacatga aaatgtaaga ccagataata gaaaacttga agaaataaga cctatatggt
    60901 gtgaaactgg catgatacct agagctcatg gttcagccat atttactaga ggacaaactc
    60961 aagtacttaa tgttgctact ttaggtgctt taggagatgt tcaaaaatta gatgggttag
    61021 atgaagaaga aaacaagaga tatatgcatc attataattt ccccgcatat agtgttggag
    61081 aagctagacc atcaagagga ccaggaagaa gagaaatagg acatggtgct ttagcagaaa
    61141 gagctttatt accagtaata ccatctcaag aagaatttcc ttatgctatt agattagttt
    61201 ctgaagtatt aagttcaaat ggttctacat ctcaagcaag tgtatgtggc tcaacattat
    61261 ctttacttga tgcaggtgta cctataaaag atatggttgc aggtatagca atgggactta
    61321 taaagcatga tggtaaggtt gcagtgcttt cagatataca aggtatggaa gaccatttag
    61381 gcgatatgga ctttaaagta gctggaacag agtatggtat aacagcaata caaatggata
    61441 taaaaattga tggtatagat aaagaaattc tacaacgtgc tttaaaacaa gctaaagagg
    61501 gtagaatcca tatactagga gagatgagaa aaactatatc tcagccaaaa ccagaacttt
    61561 caccatatgc acctaagatt gttaaaatgc aaataaatcc tgacaagata aaagatgtaa
    61621 tagggcctgg tggaaagata ataactaaga taatagacga aactggagtt aagatagata
    61681 ttgaacaaac tggggaagta tttatatcag gtattgagat tgatatgatt aagaaagctc
    61741 aagaacttat aaataatata gtagttgaac cagaagtagg aaaaacttat aaaggtaagg
    61801 taagtagaat aatgaacttt ggagcatttg ttgaaatact tccaggaaaa gaaggattac
    61861 ttcatatatc tcatatagct catgaaagag ttgccaaagt tgaagatgta ttgaatatag
    61921 gggatgaagt tgaagttaaa gttacagaga ttgatgaaaa aggaagagtt aatttatcaa
    61981 gaaaagttct tttaccaaaa ccagaacata aaaataaata acttattata taattaaaag
    62041 caaagtctta ggattttgct tttttaaata caaaaaagta gataatttta aaatgatagt
    62101 tatggatggc ttatagttct ttttctgtaa ggctttactc ttataaagaa gctatttaaa
    62161 agctgattaa tagaaagctt tattgatata tatagaatca cttaagttat atttagtgca
    62221 taaacagagc ttatttttaa tagtattaaa taagaaacaa tttgtacata attaggggga
    62281 gttttaatga taatgatggt acttaataag agtaagctca aaaaaatcat aatactaatt
    62341 ttagtagtgt tattagtatt atcaggaggg gtaatggtat taaagttatt taacaacaag
    62401 ccagtattta atttatttaa tggtgtagat ttaccatatg aaagaggtac aaaggataaa
    62461 agtggatatg ttgcattaac ctgtaatata gaccttggat gggaaacaga gtacgtagaa
    62521 tccattttag aaacacttaa aaaagaaaat gtaaagatta catttaatgt aactggaaaa
    62581 tgggcagaaa agaataagga tgaattatta aagataaaaa aacaaggaca tgaaataggt
    62641 aatcatggat ataaacattt agattattct acattatcat atgaagacaa ttatgagcaa
    62701 atagagacct ctaaaaagat aattgaagaa attataggtg aaaaaactaa attttttcaa
    62761 gcaccagcag gttcctttgg tccagaaaca gtaaaggctg ctaaagcatt agggtatact
    62821 tctatcaaat gggatgccga tactatagat tggaaataca aagaccaacc agaggtaatc
    62881 attgatagaa tgaagaaaaa agacattaaa gatagtagta taatcttaat gcatccaacc
    62941 aacgcaacga caaaatgtat agatgatatt atagctattg taagagaaaa aggactaaaa
    63001 ccagggaaac ttagtgatgt atttaagtag acaaagtata aatatttggt taagattgta
    63061 taagttgtag ttgaattaat taaaagactg acttataatg taatacatat aaaaaataaa
    63121 tataattaaa acatagtgtt ttcaataatc caatatgaaa caaagaataa attgttagga
    63181 gaatgtaatg tataagacaa aaatactgga aaatgggctt acaataattg gtgaagaaat
    63241 accatatcta aagtcaataa cattaggtat ttggataaat gcaggctcta ggatagaaga
    63301 agcacaggtg agtggaactt ctcattttat agagcatatg atgtttaaag gaaccaaaaa
    63361 cagaacatca aaagagattg ctagttcaat agataatttg ggtggtcaaa taaatgcatt
    63421 tacaagtaaa gaatgtacat gttattatgt aaaactaata gatgagcata tagatacggg
    63481 aattgatgta ttgagtgata tgatactaaa ttctaaattt gataaaaatg atatagataa
    63541 ggaaagactt ataatattgg aagaacttaa gatgtatgaa gactctccag atgacttatc
    63601 ttatgattta ttagtggaaa atatatatgc taatgatgga ttaggaatga atataattgg
    63661 gacaaaagaa tctctataca atataactag agaatccatg ttagaatact taaataagta
    63721 ttatattcca aataacgctg ttatttctat agctggaaac tttaactttg atgatatggt
    63781 ggagaaaatc aaatcaaaat ttggacactg ggaaaagaaa aatttgagta tagacataag
    63841 tgaggctaag tttaatcctt gctttatatc aaaaaataaa gatactgaac aggtgaactt
    63901 agctatctgc ctaaaaggta ttccttttga aaatgatgaa gaagtctact caatggcagt
    63961 ggtaaataat attttcggtg gaagtataag ctcaaggctt tttcagaaaa taagggaaga
    64021 aaaaggttta gtatattcaa tatactcatc acagacatta tataggaaat gtggtgaatt
    64081 aggcatattt gcaagtatga gtacagaaaa tttacaagat gtatataatt taataaagaa
    64141 agaaattgaa aatataagag aaaactatct tacagaaaaa gaaatatctg aaagcaagga
    64201 acagttaaaa ggaaattata tattggattt agaaagtact agcagtagaa tgatgtctac
    64261 tggtaaatct atgttactta gcaaaaaagt aaaaactaca gatgaaatac ttgaatgtat
    64321 aaataatgtt aatattaatt caataaagaa ggttgttgat aaggtattca atatcgaaaa
    64381 tattggtaca tgtatagttg gaagagatgt agaaaagatt ctacacttgg attaatattg
    64441 aaaaaagtaa atctctggag gtataaaata tgaatttatc tgaaatagca ggtaaggaaa
    64501 tagttaactt ggtcacagga gaaagattgg gggtcattgg agaatgtgac cttatactag
    64561 atgaaactac aggcggtata ttagcgcttc taattccaaa ggaaaaagga ttttttgcca
    64621 gaagaaaaga taagtcattt ttagaagtac catggagaaa tgtaaaaaaa ataggtaatg
    64681 acatgataat tatagaatat gagggatata tttaggagga aaaaatgagt attttagtgc
    64741 aaaagtttgg tgggacatca gtagaatcat atgaaaaaat gaatgaagta tgtaagatag
    64801 taaaagcata caaaaaaaat gatgaagaat tacaattagt attagtagtt tcagcaatgg
    64861 gaagaaaagg agctccatat gctacagata cacttataaa tttgtgtagt gcagtaaatg
    64921 atgagccaag taaaagagaa cttgatttaa taatgtcttg tggagaaata atatcaggaa
    64981 caattcttgc taatttattg aatgcacagg ggatagattc tgttttcttt actggtcagc
    65041 aagcaggtat aattacaagt gatgaatatt ctaatgcaaa gataaagtat ataaatccta
    65101 aaaaggtaaa aagagcttta gatgatggta aggttgtagt tatagctgga ttccagggtg
    65161 taacagatga tggagaaata actactcttg gaagaggagg aagcgataca tcagcagttg
    65221 ctattggtaa agctttagaa tgtgaaacag ttgaaattta cactgatgtg gatggtataa
    65281 tgactgcaga ccctagagta gaaccaaacg ctaaagtatt gagttttata gattatgagg
    65341 aagtattcca aatggctgac aaaggtgcaa aagtaataca tccaagagca gtacagttgg
    65401 ctaaaagtgg aaatataact ttagccataa agaatacaat gaatccaact tttgaaggta
    65461 caaaaatagg ttctttatgt agacacttag aagagaatat agaatatgaa caagaaagag
    65521 attttaaggt tgctgttgca aataaagata gtgtagcaca agttaagatt aaatcagcag
    65581 aagaagtgtt tacagaagta ttaaatgaga tagaaaagaa acttataact atagatatga
    65641 taaatttctt tatatcagaa aaagcatttg ttgtagaaga tgctgatata aaatcattaa
    65701 aggaaatact agataaattt gaattagatt atgaagtaaa tagagactgt gctaaggtaa
    65761 cattgatatg ttcaagaatt gctgatgaaa tgtctggtat catgtcaaag gtagttagag
    65821 gattatcaaa agcaggggta tctcttttac aaacatcaga ctcaaatatg actatatctt
    65881 gtttagttag tgaagaagat atgcatacag cagtacatgc tatacaccaa caattttatt
    65941 taaaataaac tgtataatac aattattttt taatcaaatt taagaatttc atatatatct
    66001 taatatattt gatttatttg gtaaaactaa attaaatata attttgatag gagttttttt
    66061 atgaaagatt atagagaaga taatgaaaga tttgataaag ataattgtag tgaagaatct
    66121 agttgcgaag agagagaatg tataaagcaa tttggtacca atgaaatgcc acctcaacct
    66181 cctaaagata ttcaatgtat aactataatt ggagaaattg agggacattt tataggaaat
    66241 cctcaaaaaa aagctacaaa gtacgagcat ataattccaa tgctatactc aattgaggaa
    66301 agcaatgatg ttaaaggagt gttagttgtt ttaaacactg ttggaggaga tattgaagca
    66361 ggtttagcta ttgcagaact tttaaacagt acatctaaaa aagtagttac tcttgttcta
    66421 ggaggaagtc atagtatagg tgttcctctt gctacagcag gagattactc atttatagca
    66481 ccaacagcaa ccatgattat acatccagtg cgaactactg gtcttgtgat tggtataaat
    66541 gagacttttg aatattttaa aaagatgcaa gatagaataa ttcaatttat aataagaaca
    66601 tcaaatatca aaaaagatgt acttgaaaaa cttatgcatg aaaaagatga acttgtaagt
    66661 gatgttggta gtgtattaat aggaaaagaa gctgtggatt atggtcttat agatgaagtt
    66721 ggaggactaa aagaagcact taaaaaatta agagagctta taaaagaatc tgaggaagaa
    66781 aaaaataatg attaaaattt gtttaaataa taaaatttat gatataatga tgtaataaag
    66841 taggagtgtt agtgttaagg cattagcact ttttgctgtg aaggggtaaa acttgctaaa
    66901 aataaggagt gatattaatg gccacgaaaa agaagaaaaa aaagaaggta aataccttaa
    66961 gttttaatgc agaatatcat aatttaataa caatatttat aggtgtattt ttattatata
    67021 gtttaaattc taattctatg ggatggatac ctgtgttaat gcaaaatctt tttaagggac
    67081 tatttggagg gctttcaata gcaataccat ttatagtaat tataacagga cttttaggat
    67141 tttttgatgg aaatgaatat atatataggc taagaaagac taaactatac tacataatta
    67201 ttttatttat atttgtattt tatggattat taaatgcagg aactcttcct gtagatagcc
    67261 cactaaaagg taacatgttt gatgatgtta tgaaattggg tgtaagtgga caaggtagtg
    67321 gtttgatagc aacaactatt gcgtattata tgagtaaaat atttggtata gcaggtggat
    67381 ggttaataag tatcttcgca cttatacttt ctgtaatgtt tatatttaat atttctataa
    67441 aagatttggt gtcaaatgca aaatcaaaat ctaaagcatc taaagacagc aatttaacgt
    67501 ttaaagataa aattgcaaat atgaaaaaat ctgcaataga tatgatgact gatgaagtag
    67561 atgatactac tataaataaa aaaccaggtt tctttaaagg gttaatgtca aaaggtctta
    67621 ataatgatga tgaagaagat gaatattttg aagaagaaaa tagtgatggt gtagatgata
    67681 aaactataaa aatagttgga tttaataagg cagaagatga gtatttagaa atattagaag
    67741 gaactcaaag tatgccagag ttagatgttt taaaagaatt acaaaaagct accaatgaaa
    67801 atccagttgt agatactaaa ccagaaaaaa aagttgatat agctaaatct aatttaaata
    67861 tagaaaaaac tcaacctatg agtattgtag cagagccagt taatgaggat tattcaaact
    67921 ataaaaagcc tagcattgag cttttaaata aagtaaataa gaagtctgat gaaaatggta
    67981 aaaagaaagt gttgaaaaat gcttctcttt tagaaaagac actatcagat tttggagtgg
    68041 aagcaaaaat taatcaagtt acagttggac ctactataac aagatatgaa atacaaccaa
    68101 gtccaggagt caaggtaagt aaaattgtaa atttaactga tgatatagct ttaagtttag
    68161 cagctaaaag tataagaatt gaagccccaa ttcctggtaa aagtgcaatt ggaatagaag
    68221 ttccaaatga agaagctcaa atggttggtg tgagagaagt tctagaaagt gaagaattta
    68281 ataattttaa ctctcctctt gcaatgggac ttggaaaaga cgtagcagga aaaattataa
    68341 ttggagatat aggtaagatg ccacacttac taatagctgg ttctacaggt tcaggaaaga
    68401 gtgtgtgtgt aaatacatta ataagtagta ttttatataa ggcaaatcct gatgaagtaa
    68461 aattactatt aatagaccca aaagtagttg aacttgcaaa ttataatgga ataccacatc
    68521 tattgatacc agtagttact gaccctaaaa aagctgcaaa tgctttaaat tgggcagtta
    68581 cagagatgaa tagaaggtat aaattatttg cagatgctca agtaaaagat gtaacaagtt
    68641 ataatgagaa agcggaagaa aaacttccta aaatagtaat aataatagat gagttagcag
    68701 atttaatgat ggcaagtgca aatgatgtag aagattatat ttgtagatta gctcaaatgg
    68761 caagagctgc tggaatgcac ttgattgtag caactcaaag accatctgtt gacgttataa
    68821 caggggtaat aaaggctaat ataccatcta gaatagcatt tgcagtatca tctcaaactg
    68881 attcaagaac aatccttgat atgggtggtg cagagaagct tctaggtaaa ggtgatatgt
    68941 tattctatcc acttggtgca gcaaaaccag ttagacttca aggggcattc atatcagaga
    69001 gtgagtcgga aaaagtaatt gattttgtaa aaagtcaggt taaagatgga ataaaatatg
    69061 aagaagatat aattgaaact atatctaagg ttaatacttc aaagagtagt gatgaggatg
    69121 agtttttgag tgaagcgata gaatttgtcg tggaaagtgg tcaagcatct gcctctatgc
    69181 tacagagaag atttaaaata ggattcaata gagcagctag acttatagat tctatggaag
    69241 aaagaggcat aattggagca agtgagggaa gtaaacctag aaaggtatta ataagcaaac
    69301 aggatttgca gaatttagaa ggtgaataga attgtcagtt ataaaaatag aaaaagcact
    69361 taagctagat aaagtaatat ttgtagatgt gagaactgaa ggagaatatg aagaagacca
    69421 tatattgaat gcaatcaata tgcctctttt taaaaataat gaacataatg aagttggaac
    69481 aatttataag atgcagggaa aacatgaagc aatacaaaaa gggtttgact atgtatcgta
    69541 taaattaaag gatatatatt tacaagcagc agaacttgca ttaaattatg ataatattgt
    69601 catatattgt gcaagaggcg gaatgagaag tggaagtata gtaaatttat tatcatcatt
    69661 aggtgtaaat gtatatcaac ttgaaggtgg atataaggct tatagaaatt ttgtattaga
    69721 gtatctaagg catgtaatgg atacaaaaaa ctttgtatct gttcatggat tgactggtac
    69781 aggaaagact gatttgttac atttattaga tgaaaaagga atagatgtac tggatttaga
    69841 aggcatagct aaaaacagtg gttctacctt tggttttata acttttgata aaaagccacc
    69901 atctcaaaag aactttgaaa caaaactatt tgaaagtgta tttttttcga aagagaatta
    69961 tatatttgtc gagagtgaaa gcaaacgagt tggaagtgtt acagttccaa atgaaatttt
    70021 cgaggcaatg acacgagaag gacatcatat attattagaa tgtgatattg aaaatagagt
    70081 tgatagactt tgtagagatt atatttatga taaagatgaa ggtaatatat tgattttaaa
    70141 agaatgtata aacaagttta gaaaaagatt gggtaataaa gtagtagatg attatattga
    70201 tttattagaa tcaggtgaat ataaagaact tgtaaaaaga tatcttttag aatactacga
    70261 cccactttat atgcattcag tagagaaata taagtatagt aagattataa attttaatga
    70321 tacacaaaaa gctttagaag atgttataga cttatatgag agtatattgg aaggagaaag
    70381 tgaatgttaa aaatagcatt ggaatcatta ggatgctcaa aaaatttagt agatgcagaa
    70441 ataatgatgg gaattttaaa taacaaaggc tataaattaa ttggagattt tgaagaagct
    70501 gatgtaatta tagtaaatac atgtgggttt atagagtcag ctaaacaaga atctatagat
    70561 acgataataa acttttcaga gttaaaaaaa actggcaatt taaagttgtt gatagtaaca
    70621 gggtgtctag cccaaagata ttctgaagaa ttaaaaactg aaattcctga aatagatgct
    70681 atagtaggaa caggaagcta tcaaaatata gataaaatac ttaaagaatt aagtgaaatg
    70741 catcaaattg taagccttaa tgatatagag tttgtattta atgaagattt accaagatat
    70801 atatctacac ctagctatat ggcctattta aaaattggag aaggatgctc caataattgt
    70861 acttattgta taataccaaa actaagaggt aaatatagaa gtagaaaatt tgaagatata
    70921 attaaagaag ctaagaaatt agctgaatct ggagtaaaag aacttgtggt tatagcacaa
    70981 gatacgacaa agtatggttt tgatttatat ggaaaagaaa gattatcaga acttttagaa
    71041 gaacttgcaa aaatagatgg atttaagtgg ataagggtta tgtattcata tccagaatct
    71101 ataacagagg aattgataca agttataaag aaatatgata atatatgtag ttactttgat
    71161 atgccaatac agcatgcaag taacaatatt ttaaaattaa tgaatagaaa aactactaaa
    71221 gaagatatat taaataaaat caatctgata agaagtaata taccagatgc tatacttaga
    71281 actacgataa tagtagggtt tcctggtgaa acagaagatg acttcaaaca acttgtggac
    71341 tttgttgaag aggttaaatt tgatagactt ggtgcatttg catattcaag agaagaagat
    71401 acaccagcag atagattgcc aaaccatata gatgaagaag taaaaataca aagaagagat
    71461 actttaatga tgattcaaca aaaaatatct gaagaactta atgacaaaaa gataggaaaa
    71521 acttatgagg tgttaataga agaacagata gaagataatg tatatacagg aagaacacaa
    71581 ggtgatgcgg aagaaattga cagtatagtg tatgtaaaaa gtgtagacaa tcttgaagta
    71641 ggagaatttg taagtgttca aataaatgat gcaatggaat acgatttaat gggagatgtt
    71701 ttatatgaac ttgcctaaca agttaacttt gtttagaata tttttaatac cagtatttgt
    71761 tttaattatg ttgctcaatg taccaaataa atttttaata gcttgtatta tttttataat
    71821 agcttcaatt actgatgctt tagatggaaa aatagctaga aaatacaatc tagtcactga
    71881 ctttggaaaa tttatggacc cattagcaga taagttattg gttatttcag cacttacatg
    71941 tatgatagaa gaccatcttg taagtagttg gatggtaatt ataatagtgg ctagagagct
    72001 tacagttagc atattaagag ctatagctgc tgctgatgga aaagtaattg ctgctggaaa
    72061 cagtggaaaa cttaaaacga taactcaaat ggtatctata gtgtttttat tgttaggcgc
    72121 tcagtttgaa aatgtattga tattaaatat tggtgaaatt ctcattctta tagctacact
    72181 acttacatta tattctggat gggaatatct atataaaaat aaagagcttt ttatgtcttc
    72241 taagtaaaaa attatgcttt aataaataaa aactaatgat taataaataa aaaataacaa
    72301 cttaaaattt taaaaatgta aaaaagggta tactattata gtatacctct tttcatttta
    72361 agaatatttt cttttgtgta tataattatt aataatggtt tataaataaa atgtaatgaa
    72421 taaaaatata atcattagta gcgtttttaa attgactagg tttgatttat gttatataat
    72481 taatatataa caagagaaca aatgtttgta gataaatgaa gggatggtat agagatgagt
    72541 gtagatcaag aaaaattaaa agcgttgaat gaagctttag gtaaaattga aaaagatttt
    72601 ggtaaaggtt cagtaatgaa attgggagaa gcaacatcta tgtctataga tgttatatca
    72661 acaggagcga ttggtttaga catagctatt ggtataggag gtctacctag agggagaata
    72721 gttgaagtat atggtccaga atcttctggt aagactactg ttgcgcttag ttgtgtagca
    72781 tcagctcaaa aagatggagg aatagctgca tttatagatg cagaacatgc acttgaccca
    72841 gtatatgcaa aagctttggg tgtggatgtt gataacctaa taatatctca accagataca
    72901 ggtgaacagg ctttagagat agcagaggca ttgataagaa gtggagcgat agatataata
    72961 gtaatagact cagtagcagc attagttcca aaggctgaaa tagatggaga tatgggtgat
    73021 tctcatgtag gtttacaagc tagacttatg tcacaagcac ttagaaagtt aactggttca
    73081 attaaaaaat caaattgtgt tgctatattt ataaaccagt taagagagaa agtaggaata
    73141 atgtttggaa acccagaaac tactactgga ggacgtgcac taaaattcta ttcatcagtt
    73201 agattggatg ttagaaaaat agatacaata aaacaaggtg ataaagttat aggtagtaga
    73261 actagagtta aagttgttaa aaacaaagta gcaccaccat ttaagcaagc tgaatttgat
    73321 ataatgtatg gagaagggat ttcaaaaatt ggagaccttt tagatatagc tgctgatgta
    73381 gatatagtta aaaaatcagg ttcatggtat agttacaatg atactaaact tggacaagga
    73441 agagaaaatg ttaaaaaatt cttggaagat aatttagatt taactactga aatagatgag
    73501 aaagttagag cattttacaa tttaaatgaa gaacatgaag aatcaggtac ttcagtatca
    73561 aaagaaattg tagaagaata agtaaaaata caaaaaaata actagtaatt aaagacatgc
    73621 cacgctccct attagcttga cacaatgttg aaaaaattat aaaattaagt gaggataaaa
    73681 tatctaaatt taattttaat tattaggaat attttttaat catagtgatg acattttggg
    73741 attattaacg aaggaggtgg atgtcataga tagtgtagta atgattgtaa taggtgcagc
    73801 tgttggtatt atagctggat attttgttag aaaaaatata tctgaagcaa aaattggaca
    73861 agctgaaaac ttggccaaag aaataataga taaagcacac cacgactcag aaacagtaca
    73921 aaaagaaaaa ttactagaag ctaaagaaga gatccataag tggagaacag aagctgaaag
    73981 agaaaacaga gaaagaagaa cagaagtaca aaagtatgaa aaaagagtag tacaaaaaga
    74041 agaagtctta gatagaaaat tacaaaattt agaatctaaa gaagtaaacc taagtgaaaa
    74101 attaaaggta gtggaaaaga aagaagaaga agtcgaagta ataaaaactc aacagttaga
    74161 aaaattagaa agtatatcag gaattacttc tgataaggcc aaagaaatca tcttaaccaa
    74221 tgcggagaga gatgtaagac gtgaaatgtc tataatgata aaagagatag aaagtcaagc
    74281 taaagaagaa gctgataaga aatcaagaga aattatagga tatgcaattc aaaaatgtgc
    74341 agcagatcac gtagccgaaa ctactgtaac agtagtaagc ttgcctaatg atgaaatgaa
    74401 aggtagaata ataggtaggg aaggtagaaa tataaggact ttagaaacct taacaggtat
    74461 agaccttata atagatgaca ctccagaagc cgtaatttta tcaggatttg atccaataag
    74521 aagagaaatt gcaagaattg ctctagaaaa attaatagca gatggaagaa tacatccagc
    74581 tagaattgaa gaaatggttg aaaaggcgag aaaagaagtt gacaatatta taaaagaata
    74641 tggtgaacaa gctgcatttg aaactagtgt acatgggatt catccggaat taataagatt
    74701 attaggtaga cttaactata gaactagtta tggacaaaat gtacttaaac attctataga
    74761 agttgctcat atagctggta taatggctgc tgaaatagga gcagatatta gattggctaa
    74821 gagggcaggt ttattacatg atataggtaa ggctgtagac catgaaatgg aaggtacaca
    74881 tgttgaaata ggtatggatt tacttagacg ttataaagag tctaaagaag ttatacatgc
    74941 catgagtact catcatggag attacgaacc tcaaacagta gaggctgtat tagttacagc
    75001 agcagatgca atatcagctg ctagacctgg tgcgagaaga gaaactttag aagcatatat
    75061 aaagagactt gaaaaattag aagaaatagc taattcatat gaaggtgtag aaaaatcatt
    75121 tgctatacaa gctggtagag aaataagaat aatggtaaaa ccagaagcta taaatgatga
    75181 agaaatacat ctattggcta gagatatgac taagaaaata gaggatgaac ttgaatatcc
    75241 tggacaaata aaagtaagca taataagaga aacaagagct atagagtatg cgaagtaaaa
    75301 gaaataatat ctaaataata agaaaatatt tttagaaatt taaatttgcc acaagatatg
    75361 ataatatatc ttgtggcttt taaattgttt aagtttaatt ttatataatg caaaaataat
    75421 ctaagtgcta aaagtgctac ttacaaaaga ttaataaaat aaagctttat atatgtatta
    75481 tttatataat tatccaagtt tgtttgatat aatgaagttg taaaatcaat actttactac
    75541 aaaataaata gtaaatacta cagtaaaatc taaaaatagg atataatagt attaatataa
    75601 gaagattata aataaaacct gctaatgaaa atagattatt tttagcaggt ttttaaattt
    75661 tttataataa atcttatttt tagtcaacaa gatttatttt ttttaaaact ttacttacta
    75721 ttttaaacat taattatgaa atttatcatt ttattattta cagaaagtat tctataacaa
    75781 taaatatcta tatttattgc aaaattattt tagcagtttt gtatttattt gtatttattt
    75841 tgaatttatt tactaaattt gcctataaaa agtatatata aaaatatagt tcaaaatggt
    75901 ataattaagt ataacagaag gaggtaatgt aagtgagcca atacataaat ataaattctc
    75961 agttagacgc cctaaaattg aaggagttcg agaaaatatt ttacgaaaat atcaatgagg
    76021 acgttaaagt agtgccaaaa gttactcctt ttaaaggaat aaataccgat ttgttgtatg
    76081 ttaaagatgg aagaatttta tttataaaat ttatggatac aacagaagat atatttttta
    76141 ttttagaaga agagttactt gaagttatga atgaggaata tgaacttttg aaactaaaaa
    76201 tgggacaaaa gaatagaaat ataagttata actacgttta cattatgcca tacgttgaag
    76261 ttgaggaaac atatgaattt gaagaatttg ttaataataa tataatagat aaaaataagc
    76321 ttcaagatat aatgaataag ggttcgctgg aggagtatct taatgatgag aatgatgaaa
    76381 taaacttaaa tttattttta ctagacatat gttcagaata ctatataata aatgataaac
    76441 ttcatctaaa tgaaaaattt aaaaaaattt cattctacaa tgatgactat aagtatacag
    76501 caactatgat ggaagacgtt caaattaaag atgttgtttc tattaaatat gggaatacac
    76561 ttattgaagg tggttctggt ataggcaaaa cagcaattat gctttctagg gctataaaat
    76621 tagcaaaagt atatccacat cataaattag tcatatttac acatacaaaa caattgtgca
    76681 atgagcttcg agagaggata gagttattat acaaagataa taacaattta gaagttcaca
    76741 catttagttc ttttatattt aaactagcta aaaaattcaa tttaattgta gattataaca
    76801 tgttaaaaaa tgattacgaa aagaccttta ataatcttgt aaaacaagca cagaacatta
    76861 taaaaaataa aaatatgttc aaggctattt ttattgatga agcagaaagc tttttagagt
    76921 atgaaataga ttttataagg gagtttttat ataaaacaaa attcatattt aatgtgtgtt
    76981 cttgtaactc cttgaatatc tctaatagat tgaatatatt taaaaaatta tataatggta
    77041 tagaatttga tgataagatt atcttaagta aaaattatag acaagctaaa gagattgtag
    77101 attttacaaa taaattttca aataattcta actcatatat caacgaatta agaccaaata
    77161 cagaatttag tactttcttt tatactaaag cacttagagg tggaaataag tctgttgata
    77221 taataaaagt aagtgacctt gatgaccaaa taagttctgt aatctgggaa attgagtatt
    77281 taataagtaa aaaaggtctt gattattctg aagttgctat cgtttatcct tataataaga
    77341 agaaattaaa aagtggaaaa accatttact ttcaatatat gttaaaaaaa gcattggaag
    77401 aggcaaaaat tccttatata tgtgcagaag ataatttgac aaatataagt aagaaggtag
    77461 gaactacaat agcaaatata tatgcaataa agaatttaga gtataaagcg gtaatagtat
    77521 gtgaattaga gatgttatac aatcaaacta taaatgatat tgaacaagat tatcaagtaa
    77581 atgactttgt aggagattta aataaggttt atttagctat gagtagagca acagactacc
    77641 taagtatagt aacaactttt aatgaagaag caagtgatat aataagactt attacagaat
    77701 caaaagatat ttagtaaaaa aatatttgta atttaagaaa ataaaaagag actgagattt
    77761 gtaaaataaa ctttaccaat tcagtctctt attttttagt ccactttccc aatattatca
    77821 agaggtaata gtctcaccat aaccttacca agaatttcat cttcatcaac catacctaca
    77881 tcagggaatc tactatcatt actattttct ctattatctc ccattgcaaa tagtttacct
    77941 tttggaacaa cagtatctat atctccagaa gtatagttat tgtgtatata tggttcattt
    78001 aataattttc catttacata cactttagaa tttgatattt ttattctgtc accttcagta
    78061 gctataactc tttttattaa gtcttttttc tttcctgttt ctccatcaac taaattggtt
    78121 ttaaaaacta caatatcgcc tttttcaggt ttaccaacct tgtatgatat cctatttaaa
    78181 atcagataat ctttatcatc taaagtagga tacattgatt ctccacttac aacagaaggt
    78241 cttataaatt gtagaattac aaatgcaagt acaatagcca tagctattga cttaatccaa
    78301 tcaaatattt cttttttaac actcataact tttctcctta tcatttgtta ttaaattaga
    78361 atacattata atagaaagaa ataagcaaga accactatac ccaagactat tctataataa
    78421 ccaaatactt tgaagtcatg ttttttgata tagtccataa aaaatttaat aactacaatt
    78481 gaaacaacaa atgctactac agaaccaaca cctaaaataa gccattcaaa tccagtaaat
    78541 ccaaatccag cttttagaag ttttaatgca ctagctccaa gcattgtagg aatggctaag
    78601 aagaatgaaa actctgctgc tacatatcta gaagtaccaa gtaatactgc acctattata
    78661 gtagaaccag acctagatgt acctggtatg agagctagac actggaataa tcctatacaa
    78721 agagctaatt tatatgtaac ttgagaaaaa tctttatact taggtctttt atttctcttt
    78781 tcaagcccta tcattattat accatagaca ataagagcaa tagcaactac tgttgaatta
    78841 aagaatactc tgtctatgtc atcttcaaac agtattccaa taactccaga tggtataact
    78901 gcaattataa ccttaagcca taaacgaact gtttcttttt tctgtttaat attctttgca
    78961 ctatcaaaag gatttaactt tctaaaaaat ataacaagta cagctagtat tgaaccaaat
    79021 tgaattacaa ctaaaaatgt atttataaat gtatttgaaa aattcaattt tataaactca
    79081 ttaattaata tcatatgccc tgtactactt actggtagcc attctgttat tccctgaact
    79141 atgcccaaaa tgactgcctt aaaaatttca agcaaactaa atgtttccaa atcaaaatac
    79201 ctccaataca aatttatagt agcatatttt attcatagat taataaaaaa atgccacctt
    79261 ttactaactt ataataccat agtactgtgt agtgcacaat ggaagattga tattttcata
    79321 aaaccttcat aatataacaa aataaactta aaagttatct attgaataag gggtatattt
    79381 gagggggaaa tatatggtat agtaaaagta tagctatttt attttatgaa aaggaaagga
    79441 gttattatgt atagtacaaa aatactagat gattatgagt atgaaacttt taatgttttt
    79501 tctacaaaat taaatccaaa cacgaaacac gattatttat caaaggttat actgtttaaa
    79561 gaatttttaa aagggaaaga attgatttat gctacaaaag aagattgtaa aaattttgta
    79621 gactatatac agactaaata tgcgaaatca acttgtgaaa agatatatag ttatttacat
    79681 agtttttata acttcttaaa aaaagaagga tacatagata taaatccatt tagatatgta
    79741 gaaaaaccca cagtaacaag aataaaaaca aaagatgatg ttctaagtat acaagaaata
    79801 aataaactta taggtatcct accaaaatta aatataagag atagagtaat aatagtctgt
    79861 ctagttacta ctgggtgttt attaaatgaa ttagttagct taaagtggaa agaccttatg
    79921 gtagatgaaa acgataactc atatgtaagg ttaggtaagg gaagaaaaga aagagtagtt
    79981 aaattacatc catacttttt taaactttta gaagattaca ggaattattc tgggcttcca
    80041 gaggtaataa tacctagtga tgattttatt tttacaactc aaaagagtaa ttctataaca
    80101 gatagaaatg tcagacttat agtcaaaaaa gcattagatt tagctggact ttctcaatat
    80161 tcagcaagag attttagaca ttcatttgca gcaataagtt taaggcttgg ggcagatgaa
    80221 agtgatgtaa aaaatcagct tggatggagt gataaatact atgcaattag atataagtat
    80281 gtattaaatt ttgttgatag tgaaatagtg gattacttaa ttgaaaaaga taatttggat
    80341 ataaataaaa aatagtaata aataaaaaat actatatata gatgtgaaca aaaaataaaa
    80401 aagtcttgtt atagttcgta aaattatata taattattta tgtactaatg tgtacacagt
    80461 aatcacacga caaaagattt aaggaaggtg ctaatataat gatagataat aaatatacta
    80521 cttactcaaa cccacttaca gacagatatt gtagcaagga catgagttat atattttctc
    80581 cacaatttaa attctctaca tggagaaggt tatgggttgc acttgcagaa ggtgaacatg
    80641 agttaggaat caatataact gaagaacaat tagatgagct aagagctaat atagataata
    80701 taaattttga tgaagctaga aaaatagaaa aagaagtaag acatgatgta atgtctcacg
    80761 taaaagctta tggtttacaa tgtgaaaaag ccaaaggaat aatacattta ggagcaacat
    80821 ctgcatatgt tggagataat acagatgtta tacaaatgaa tgaagcttta aaacttctaa
    80881 gagtaaagct tgtaaattta ataaacaatt taaaagaatt tgcacttaag tacaaagata
    80941 tgccagctct tggatttaca cacttccaag ctgctcaact tacaacagta ggaaaaagag
    81001 cttgtttatg ggctcaagat ttaattcttg atttggaaga tttaaactat agaatagata
    81061 acatgaagtt aagaggagtt aaaggtacta ctggtactca agcaagtttt ttaagcttat
    81121 ttgaaggaga ccacgaaaaa gtaaaagagt tagataagaa aatttgtaaa aagatgggat
    81181 accattcttc ctatgcagta agtggacaga catatactag aaagttagat tatcaagtaa
    81241 taagcatact atcagggata gctcaaagta tgcataagat gactaacgat ataagacttt
    81301 tacaaagttt aaaagaatta gaagagccat ttgaaaaaaa tcaaataggt tcatcagcaa
    81361 tggcttataa gagaaaccca atgagaagtg agagaatagc atctttatct aagtatataa
    81421 tctctgaatc tataagccct gcaatggtac aagccactca atggttagag agaacattag
    81481 atgactcagc caataagaga ttggcaatac ctcaagcatt tatggcagca gatgctatac
    81541 ttgaaatagg gataaatgta actgatggtt tagtagtata tgaaaatatg ataaataaac
    81601 gtgtaaatga agaacttcct tttatggcta cagaaacaat acttatggaa gctgtaaaaa
    81661 gaggtggaga tagacaggaa ttacatgaaa taataagaga atattctatg aaagctgcct
    81721 atagagtaaa gcacgaaggt aaggataata acttaattga acttataatg aatgatgatt
    81781 catttaaaat gagcaaggaa gaaatactat ctataatgga cccaaaaaac tttataggta
    81841 gagctccaga acaagttgta gaatttgtaa atgaagttgt agaacctgct ataaaagatt
    81901 ataaggaaga cttaggaaaa gtagatgtgg acctaagagt atagaattgt acagataaaa
    81961 tataattaaa aacggctatc ttatttataa ataagatagc cattttaatg ggctagcgtc
    82021 ttctcttcag cgctgtgaag agttcttctt tacttactat accatgaatt taataaaata
    82081 gctatataaa taatatttaa tagaaataat ataaataaaa ataaaaaaat gataagatta
    82141 ctaattaaat ttaaacattc agcaaaaact attgtacttg caatattttt aatgtaaact
    82201 gaaataaagt tatttagata atttaataaa ttttaaaaca accgaggtga ttatatgaac
    82261 tatatagtaa aagataccat aagtttttta gtaaaaacat ttcctaagat ttattctagt
    82321 ctgtacttag aagacctaaa aaaatttgca ccagattata atgtaaataa aacacaatta
    82381 agagcattag ttttcataaa aaattatgga gtaataagta tgactgattt atgctctaag
    82441 ttaaatatag aaaaaggcag tttaactagt atggttgatg atttaactga taagaagtat
    82501 gtaacaagga aaagagattt agttgataga agaaaatatc taattgacat tactgaagag
    82561 ggagataaga tagcaactga ttttatggat aaattaagtg atggtttagg agaaaaactt
    82621 tctaaattaa ctgaagaaga cagaaaaaaa tatttagaag caataaatac tcttcaatat
    82681 atattaaaca aagaagaatt tagatagaaa aaatataaaa aatttttata tttaatagta
    82741 ctaagattaa ttctttgtta ttcatttaac tatataatta taagtctaaa tacaatctaa
    82801 aaagtacatc ttaaattttc ttgatgtact tttttataat ttcttataca ttttcttatt
    82861 tgttagtacc tactcatacc tctttgtgta atttatattt ttccatttta tattcaataa
    82921 ttttattttc taatctcttt ttaaatttct atatatcaca atgttactat gtctttgttt
    82981 gaaaaaattt acagttttga aaaaattact atttatgtaa aaatatttta aaacaaatta
    83041 taaagtttca aaaacaaaat aaaaatatat aattatgaca tagaaaacgt tttaaaaatt
    83101 taaaaatgga gggatagaaa tgaaacaaaa aatgaaagag ttttttttac agttaggaaa
    83161 atcattttta ttgccaatag cattaatatc tgctgcaggt atatttttag gaataagttc
    83221 agcattttca aatcctaata tagttagtga tatacctttt ttagaaaata attttattca
    83281 aggaatattg ggttttacaa aagctataac aggagtactt tttggaaact tagcaatatt
    83341 ctttgctata tcaatatctg ttggtcttgc taaagaagaa aaagcagttt ctgcattttc
    83401 tggttttgtt ggttatttag tattacacac tagtgtaaat tatatgttag ggtgtagagg
    83461 tattcttgct gaacctgaca tgatgagaga aatgggtcaa gctgtaactt taggcataca
    83521 aacattagag ttaggagtat ttggtggaat tgtagttggt ataataacag catcattaca
    83581 taataaatac tataatataa aactgccaga ttatttaggg ttctttggtg gaactaggtt
    83641 tgttccaata ataacaacag tagtattctc tattttgggg ataataatac catatatatg
    83701 gccatatgta aatacaatta ttcagagtgt aggtattggt atagctagtt taggatattt
    83761 aggaaccttt gtatttggat ttcttgaaag gcttttaata ccatttggat tacatcatat
    83821 attaaatgct atgtttagat ttactgaagt aggaggttct ttagttgtag gaggacaaga
    83881 agtatttgga gcattgaaca tatttttagc tcaactaagt gaccctgaaa caatcagttt
    83941 ttcaacagaa gcaactagat ttttagctca agggaaaata cctataatgg tatttggtct
    84001 tcctgctgca gcatatgcca tgtataaaac tgcaaagcct gaaaataggt cgaaggttaa
    84061 aggtatatta ctagctggtg ctttagcaac atttgtaaca ggaattacgg aaccattgga
    84121 attttcattc ttatttgtat caccaatatt atttgttata catgcatttt tatcaggtat
    84181 atcatttatg atgatgcata tatttggagt agcaatagga aatactcaag gtggcataat
    84241 agatttagta gtatttggag ttatgcaacc aaatacaaag tggatttatt ctataatact
    84301 tggtttagtg tatgcactgg tttattataa tgtatttaag gttttgatac ttagatttaa
    84361 cttacaaact ccaggacgag aagaaataac agatataaat tttgatttag aacctttatc
    84421 aaataaagta gaaatagctc aaagtggaga aactactaag agagcattat ccataattaa
    84481 atatttaggt ggtaaggaga atatagaaga tataacaaac tgtataactc gcttaagagt
    84541 agtagttaaa gatatgagta aagtagatga aaatgctttt aaaaaatata caggtgcaat
    84601 gggcgttata aaagtatctg ataaagatat ccaaataatt tatgggccat ctgtatctca
    84661 agtaagagac gaagtttctt ttgcaatgtc tatttaatgt ctatctaatg taaatattaa
    84721 aaggcaatac taatttataa tttgtattgt cttttttgta gtataataaa cataagataa
    84781 atgttgtata gtgtatattt atataataaa tatgagaaag ttgtttaact acaaatcatt
    84841 attatggagg tataaatgaa cctaatagac aaattagata taaatcaaaa aaaattatct
    84901 acaaatgaaa tatctctttt aaactatttt ctaaaaaatt ctgaaaaaat aaatcaaaaa
    84961 aagattaaag atatagcaaa tgaaactttt aattcgactg catacatagt aaggttttgt
    85021 cagaagctcg gcttttctgg atatagtgaa tttaaaaact ttttagtttt ttcatattca
    85081 aatagaaatg aaagaaataa ggagtttact aaaagtcaaa gtgatatttt tactgatgtt
    85141 atggatacac aaaatttaat aaatgtagag aatatagata tgtgtttaaa tgaaatacat
    85201 aattctaagc atatatattt ttttggtgtt gggtcttcta gattagtatg tactgaaatg
    85261 tctcaacgtt tttcagctat aggtgtaaat gtaaaatact atgatgattc aactctcatg
    85321 tatttggctg catcaaatat tactaaagat gaccttgtaa ttgctgtatc tatgtctgga
    85381 gagactgctc aagttattaa ggcatgtaat atagcaaaaa caaatcaagt taaagtaatt
    85441 tctctgacaa atataagtgt caattcatta tcaaatatag ctgatataaa attatttgta
    85501 tcttctccac aatataattt taatagtgtt aactatacgt ctagagtgcc agcactttct
    85561 cttatggaat atatgtttca taaatacatt gaaaaataca atagatgaaa aaaattacaa
    85621 ttttgaaaaa aatactaaaa ttgaactatt tttaatgatt acctaaaagt attcatgtag
    85681 aaaactttat atattataat catcttacaa gttagttaat aaaaaacagg ggtgattaat
    85741 atgacaatga aaaaaagata caatatagct atagttggag gaggcagtac ttggactcca
    85801 ggacttttaa agtctttatg taaaatgagt gatagatttc ctctaaataa agtaactatg
    85861 ttagatgtag tagaagaacg tcaaagatta ataggggaat ttggaaaaat attatttaaa
    85921 gaagaatatc ctaaagcaac acttgaatat actacaaacc cagatgaagc atttatagat
    85981 gtagattttg tatttgttca aatgagaact ggtggtctta agatgcgaga attagatgaa
    86041 aagattcctc tacaatttgg actggttggt caagaaactt gtggagctgg tggatttgct
    86101 tatgggttaa ggtctatagg tgatatgata gaaatggtta agactgtaag aaaatactct
    86161 cctaaagcat ggatattaaa ttatacaaat cctgctgcta ttgttgcaga agcattaaaa
    86221 agagtatttc cagatgataa aagattactt aatatgtgtg accaaccagt taacttgtta
    86281 aggtcttatg gaagattgtt agacatggat tcaagaacat ttgagcctgt atactttgga
    86341 ttaaatcact ttggatggtt tacacatttg tatgataaaa atggtgaaga tttggtacct
    86401 aagataaaag atttagtagc aaactctgga ttccaacctg ttgatgcaga acaaagagat
    86461 aaatcttggt tagacactta tggaatggtt aaagatatgt tggaagatgt accagattac
    86521 ttacctaata catatgtaca gtattatcta tatcctgata aaaaagtagc taaatcaaat
    86581 ataaattgta ctagagcaag agaagttatg aatggaagag aaaagcgtgt atttgaagaa
    86641 tgtaaatctg ttatagaaaa aggaacatct ataggttcta atttagtgca taatgatgct
    86701 catggggaat ttatagttga agttgcagaa gcaatagctc ataacaaaca ccaaatagcc
    86761 atagttataa cagaaaataa tggggctatt aacaacttac ctgatgatgc aatggtagaa
    86821 gtagctgcga ttcttacaaa gaatggaccg agacctttac atgtaggtaa tataccaaca
    86881 ttttataagg gactgttaga aggtcaacta gcttatgaaa agttagcagt tgatgcatac
    86941 tttgaacaat cttatgaaaa agctatttta tctttaacat taaatagaac tataatctct
    87001 ccaactaagg caagacaagt tttagatgct ttaattaaag tgaataaaga ttactggcca
    87061 acactatata aagaaaatga aaaatagtca ggtctaagtc ttaattaata tattaattaa
    87121 gaaatgtccc cttttcaaat aatatctgaa aaggggacat tttatatcat taaatttata
    87181 taaattaagt ttaaaaaatt atttttgtaa agctacatat tgctctaaac cttcttttaa
    87241 taatgtagca gctctatgaa ggtctttttc atttaagatg taagctaatc ttatttcatc
    87301 acgtcctaaa cctggagtag catagaatcc ttcagcaggg caaaccataa ctgtttcatt
    87361 atctttgtta aattctttta acatccaaat tgtgaaatct tctgcatttt caactggtaa
    87421 tttagcaact atatagaaag caccagttgg ttttttacat ataacacctt caaccttcat
    87481 taattcattg tataatacat ctcttctttt tttgtactct tcattaactt ctttgaagta
    87541 agaaacagga gttttgtata actcaacagc tcctatttgc tctaatgtag gaacacaaag
    87601 tcttccttga cataatttaa gtatttgagc gataagacct ttatttttgc aagcgataga
    87661 accaattcta gcaccacaag cactgtatct cttagaaaca ctgtctatta ttataactct
    87721 atcctgtaca ccctctaagt taccacagct tgtatactca agcccatcat aaacaaattc
    87781 tctataaact tcgtctgcta ttatccataa atctttttct ttagctattt cagctaggat
    87841 attaagttct tcttttgtat aaattgcacc agttggattt cctgggttag aaagaattat
    87901 agccttagtt ttatcatcta ctttagacaa tatttcttct ttagatggaa ggtggaaacc
    87961 gttttctgcc tttgttgtaa cagcattaac ttctacattt acagattgac caaatccatt
    88021 gtagtttgta tagaatggtt ctggaactaa tagattatct cctgggtcac aaactgccat
    88081 catagtgaaa agtaaagctt cactaccacc attagttact aataattcat ctttttcaaa
    88141 attcatatcg taagttttat agtaattttg aagtgcttct aataattctg gaataccttc
    88201 tgatgtagca tattctaaga cttcgctatc aaagttttta acagcatcaa aaaatccttt
    88261 aggagttttt atgtctggtt gtcctatgtt taagtgatat actttgattc ctttatcttt
    88321 tgctgcttgt gcaaatggaa caagttttct gattggagag gcttgcattg cactaactct
    88381 gtttgaataa ttcattttaa taccccctat ttaatttaaa tacgtatatt gtattatgta
    88441 aattgtatgt ttgaatacaa gacatcttta caagataata ataacatact tatgggtaaa
    88501 aatcatcaaa aaaaattaat atagctttaa aataaacttt taacaaatta tagtaaaata
    88561 cccatgttta tgccactaaa ttatgtattc ataaattaat ttatagtaag ataatattct
    88621 gatacactga tagtgatttt ttagttataa tctttcagct atagacaaaa tatataataa
    88681 taaatatgca aaattataaa aaatattata aatttattta acagatacga taaatatcat
    88741 ataattatat taaaggctat taactaagag gtgttaatta tgaaagaatt aagaatagat
    88801 ccaattacta atgatgttgt tatatttgct acagataggt taaaaagacc tttagataca
    88861 gcagatatcc caaatgaaga tgaagaaact aatgaatatg atgaagaatg cccattttgc
    88921 aaaggaaatg aagctcatgc aactgatgca ttatttgaaa tagaaagtga agaaggatgg
    88981 cttgtaaaat ctgtctacaa taaatttcct ataattgatg atatggcaag agatgtatat
    89041 ggtgttcatg aagtaatgat agagagcgat aaacataatc gtagttttta taacatgagt
    89101 caaaaagaat ttgaagatgt tttttttatg tatagaaata gatttagaga tttgtcgaaa
    89161 gatgataaag tagagtatgt tagtatcttc aaaaacttct tgagaaaggc aggagcatct
    89221 ttgatgcatc cacatgctca aatattgtct atgtctttta ttccacctga aattacgaat
    89281 gaactgttag tttcaaagga gtattatgac agcaataaaa gctctttgta tgatgattta
    89341 atagaaaatg aaataagttt agatagaaga gttgtttata atggagaagc ttttttggta
    89401 cttataccat atgcaaccaa gtatagtgga gaagtaagaa taatatttaa agataaaata
    89461 gagtttggtg agttaaatga taataatata caggagcttt ctacaatatt tgaaaagttg
    89521 tttaagaagt tatacaatat caatggatat atgccattta acttatgtat tcacactcat
    89581 ccaacaaaga ttgaaacaaa atcgtatttt aatgttcata tgcacataat cccaagaaaa
    89641 tataattttg gaggatttga acttggaaca aatatgtatg tttcttcaat gagccctgaa
    89701 gatttaacaa aaaagttaaa aattgattaa aacatatatt tttaggtatt aagtaaatag
    89761 taattataga tgaaattata gtatagtatt gttaaaataa aagtaaatta agaatttaca
    89821 ataaaattgt tgaaaagccc ccatctttag ctatggggag tgtgtcaatg tttagatgag
    89881 gagtataagt atgaaattta tatcatggaa tgttaatgga ataagagctt gtgttgggaa
    89941 aggattttta gactttttca aagaagtaga tgcagatata ttttgtttac aagaaactaa
    90001 attgcaagaa gggcaaatag agttagattt accaggatat tttcaatatt ggaattatgc
    90061 tgagagaaag ggttattcag gtactgctat atttacaaaa aaagagcctt taaaagtaat
    90121 gtatggaata aatatagaag aacatgacaa agagggtaga gtgataactc tagagtttga
    90181 agatttttac tttgttacag tatatacgcc aaattctcaa tctgaattaa agagactaga
    90241 atatagaact agatgggaag acgactttat agattattta accaaactag ataatcataa
    90301 gcctgtaatt gtgtgtggag atatgaacgt tgcacataaa gaaatagatt taaaaaatcc
    90361 taaaaataat atgaaaaatg caggttttac taaagaagaa agagagaagt tttctaaatt
    90421 attagacagt gggtttatag acacatatag atattttaat cctgataaag aaggcgttta
    90481 tagttggtgg tcatatagat ttaatgcaag aaaaaataat gcagggtgga gaatagatta
    90541 tttttgtgca tccaaaaaat tagaagatag attagtaagt gcggatatac acactgaaat
    90601 attaggttca gaccattgtc cagttgaatt agagataaaa taaaaattaa ttacgataaa
    90661 aattgggctg tagatataaa tttaaagtta actagttttt taatctacat gcctattttt
    90721 tatctaaata aactctattt gttttttctt tgcttaacat tttctaatgt aaattgattt
    90781 gttttcccca tattataagc taagttaatg atttttttct cgtctttagt taattcacga
    90841 tttaaaattt tcctaaattc atcaaataac ttatcataat caactctttt tttattagaa
    90901 tatcttatag ttttaggttt tatactcgta taaagatata tatctgggac tatacttgga
    90961 ttgtatatct taataaaaac tttagcagta taatatgcat catttaaagc attgtgataa
    91021 gacatttttt catcaagttc caatatagaa atagcatttt gtaggccaat gctttttcct
    91081 gctggattat tgaaatattt agatgcatgt tgttgtatat taatataaga tttaggtaag
    91141 gaacttgatg gtagcttgtg atagttgata ttcctgtata attcctttaa atctccaact
    91201 ccccaaacac ataatatagg gtcttgtgat gatataaatt ttataaaatt gttgtagacc
    91261 tcagggaaag taggcgaatc attaaaatca gaatttttaa tattagtcat acgactaata
    91321 aagggatgta tgtctttata aattgtaggt tttacatagc tattaaacgt atctattata
    91381 ttgaatttag aatccaattt aattgctcct atttgtataa tttcaaaagg acacttttca
    91441 ttggatacag ttttattgag ttttttatca aatccttggt taaattccaa atcgaaaatt
    91501 atgtattcca taaagtttat ctcctaaatt tttttattat ttcttttact atagattata
    91561 ttataaataa aattaaattt tcaaataaaa atacttttat tttagtatac cccatatttg
    91621 taaaaatgtt aaactattgt atgtataata ttttttccaa taaaaaatat tgcgaacttt
    91681 ttatacttga tatataataa tataaataaa aacacgaata aaacacgaat aatttgcaag
    91741 aaaaattcat gaatgtaagg aaaatgaaat ttatcttgta tttaacaaaa taaaatatac
    91801 ataaaaatta tgggagagtg gaaaaatgga tagtctatta tacgtaatag agaaagataa
    91861 acacactaat gaagaattaa gagaaatcct aaaaagcaat aaaaatataa gatttgtttc
    91921 cttaatgggg gttgatttag gaggaaatgc aacagatgaa aagattcctg tagaattatt
    91981 tttggaggat atagataaat ttttggaatc agctatacag actgatggtt caagtgttga
    92041 gctttataat atagctacat taaataatgc gaaagtagat ttaatgccag ataaaagttg
    92101 tcattggtat gtagattaca atatggaata tatagacgaa gaagtaggtc tacctgttgg
    92161 aacattaaag atacctgcat ttttaataca tgataataaa aaagtatgtt ctagaggagt
    92221 acttcaaaaa gcagataagt actttaaaaa gtcaatgtat gaaatattta gagaatatcc
    92281 acatgtaata aataacatag gaatagattc agtagatgat atagaggaaa taatgttaac
    92341 agcagctaca gaacttgagt tctgggttaa tactcctgag gataaagctg acttagagaa
    92401 attatatgta tcacaaagcc taaaagagca atactggaaa agaactcatg gtattataag
    92461 aacttgttta gagaaaagtt taattatact tcaaaagcta ggtgtaaacc ctgaaatggc
    92521 tcacaaagag gtcggaggaa tacaaagttc tattagtata gatggaagaa caaaccatgc
    92581 tatggagcaa ttagaggttt cttggaagtt ttctacacca ttacaagcag cagacaatga
    92641 attattagta agagatgtta tagaggatgt atttacatca catggactag aagttacatt
    92701 taaagcaaag ccaattcatg gagtagcagg aagtggtgga catacacatg taggagtaag
    92761 tgcgaagtta aaggatggaa gtataaaaaa tctatttgct ccaaaagatt taaaagaaga
    92821 ttatctaagt gaactaggat atggggctct tatgggactt ctttacaatt atgaagtatt
    92881 aaacccaatt gtaacagctt ctaatgatgg atttaataga ttagttcctg gatttgaagc
    92941 tcctgtatgc atagttacat ctttagggca tagttatgag attccatcaa gaaataggtc
    93001 agtgcttgtt ggattaataa gagatatgaa aaatccaaag actgtaagat ttgagttaag
    93061 gtcaccaagc cctctatcta acacgtattt agtaatagca ggatgttatc aaacaatgtt
    93121 ggatggtata aaagcagcag ctaagagtgg tcttagtaca aaagaacttg aaaaagagtt
    93181 atctaaaaat gtaggtgaag aaagtttcta tttagaaaaa gatagagcat atagagatga
    93241 aaatgatgta tttgaacatt atagtttgga agaaagaaat gcaagatttg gaataccacc
    93301 ggctacagtt tatgaaaata tgaaaaactt agaaatatat gcttcaaaat taaaatcttt
    93361 aaaacaaggt gatgtattta ctgatagtat aatagaatca tttaagattg gagctataga
    93421 taagtggcaa aaaaaattaa aaactagaat aatagaggct gggattcaaa aaataagaag
    93481 tattgtcaag atacacacaa aagaaaatat ggatgcgctt gatgaggtag tttggaactc
    93541 aatatcggat ttaaagttca atattatgaa ggatacttta actagagaat cactattcac
    93601 tagagtgaga gaagctatag aaaataagga ttaccagact gcttcagatt tacaaataga
    93661 attaaagaga agtatggaag aaatacaaca actgtatatg cagtacaaga aaaatatata
    93721 ctaatataac aatttgattt tgatatgata aaggcaatca agtattatta aacactatga
    93781 gtaaattctc aagtgtaaaa gcatacttga ttgcctttaa ttttatgttt gaaatttttt
    93841 aatagtacaa tttaactgta atgattatct attaattctg atatataatc agcaattttc
    93901 tctggatgaa taactgtttt aaattcttct aaattttttt tcataaagtt tattatagaa
    93961 tcaaattcat ttgatactaa tttataaaat atgtttttaa ggtctaggtc atcactataa
    94021 atcatgccaa gacccttatc tattataaat ttagcgtttt caatttcttg tccaactttt
    94081 ggcattttca cgagtactgg agtttgtgat tgaatagctt caaatatagt tgctcctcca
    94141 ggcttagtta gcattaggtc acattctctt attagattat acatgtcgtt tacaaatcca
    94201 agtactttaa tattttttag aggtttttta tgagttagat tgtcatataa ttttttgttt
    94261 ttaccagtaa ctattgtaat ttctatagaa ttactatgtt cttcaataaa ttcatctatc
    94321 caatgcataa aatcctcatc tatatcaaat aggcctcttc ctccacctag aagtaatagt
    94381 ctatatttat cacaacatag ttctttactt tcaatttgaa atctcttatc aacaggaact
    94441 ccagtaacct ttatggagtc tggatttatt cctttctgaa aaaatctatt ttttatttca
    94501 ggagaaggaa caaaatacaa atctgtattt tcaaaaaccc attccatact atctacaaca
    94561 tctgttataa ctgtaagtgt aggtatattt atatcaggat tttttatctt aaagttattt
    94621 acacaagcag ccgctagtgg aaatgtagag ataatcaaat ctggatttat atcagcaata
    94681 tactcagaaa gtttaggtgt atataattta tgagataaat catgtcttga atcaaacgat
    94741 ttcttaaagt aataatagta attatataat ccaggagtat attttgtatt gttttcataa
    94801 agttttacca taggtttatt catcatggga atacttgcat ttataaagtt ttgtataaca
    94861 acattatagt tactatattt ttcaataata cattctttga ctgcttttgc agcacttata
    94921 tgtccagcac caaattgagc agttaagatt aatattgttt tatcatcttt cattttagcc
    94981 aatttatcac cactttcata aaatatatct gattagagta ttatacattt atagaaggat
    95041 ttaatcaaca agaatattta aaaataacta ttgtgcagaa catagtactg tgttattatg
    95101 aggatataag aagttttaac atagtacctt gtaaaacaca atactgtgta tttaaagaaa
    95161 ggatggagta tatgaacaca caatttagaa agggtgtttt agaaatttgt gtacttgctc
    95221 tcatatctaa gaaagatatg tatggatatg agatagtaca taacatctct aaagtaatag
    95281 atgtaaatga aggaacaata tatcctattc taagaagact tacaaaagat ttgtatttcg
    95341 aaacatatat actagaatct aatgaaggtc ctgctagaaa atactataga ataacttcac
    95401 taggaaaaga gaatttatcc aatctgatgg aagagtggag agaatttgta aaggctgttg
    95461 agattttaat aagtgaagat gagggaggta atgaacttga ataaaactga gtttcttgaa
    95521 attttaaagg attatctaaa aaaagatttt tctgagagcg aagttaatga tatattgaga
    95581 gattatgaag agtatttcgt agatggtctt atagagggaa agagtgatat ggagataata
    95641 gcatcacttg gttcaccaaa atctatagcc aaagaactta tcttgcagac taaagaaaaa
    95701 aatattgaag aggaaaaaat aataaataca gatgttttga atgataagtt tagtaaattt
    95761 aaatcagata tgaaaaaagg ttactctatc ttaaaagatg aagcaaaaga aaagtatagt
    95821 aaatcaaaag aaaatataga tggaaaaata atgaatacag atatattaaa tggtaaattt
    95881 agtaggttta aatcaaatat aaaaaaggat tactctatct tgaaagatga agctaaggaa
    95941 aagtacaata aatcaaaaga aaatataaat gataaactta caccaagtat agaagaaggt
    96001 gtagggggat tatctagaca agttataaag ggattattag tagtgttatc tttatttcta
    96061 attgttccag catttgcgtt tgtatgtgct attgtatctg ttactattgc attagtatgt
    96121 tcattaattg cttttgttat attaattcca tttgtgatta aatttatagc aatggttcca
    96181 gatgttatga tgttttgtat tttcgcaacc atagcatttg tagggcttga gatacttgca
    96241 tggcaaattt tattatttgc tataaaacta ggtaaacaat tactaaataa ttatatacat
    96301 tggataaaga gaaaaaatat ttatataaag gcaaatgaaa agatggaaaa aagaaaaaaa
    96361 gctactttaa atgatgaaga tttgaataaa gacattaatg aagattcata taataatgat
    96421 tactacaata gagaagaaga aagcataaaa gaaactgatg aatataatga tgatagtata
    96481 aattttgagg cgatatataa ggaccttgaa gatatagaaa ataagaaagg agaagataaa
    96541 catgaataaa aaacttgcta tatttgctgc agttttattg gtaataggta taatagggac
    96601 aacatggtca gggattttag ttatgccaag cctaataaac tttggtttag aaaaggaagc
    96661 tgaatttaaa aaagaaaata aactttatca agaaaaagta aatattgaca agttagatat
    96721 atctgttgac aatataaacg ttacaataaa gaaaagttca agtgaagatg tgcgtgtaac
    96781 aacaagagga aataatgagt tttacaaata caatgtaact ttaaaagata agactttagt
    96841 tgtaaaaggt gaaagaaaat atgaaaataa aattaaaaag attaaaaatt tcgaccaatt
    96901 attaaataca tctataaata gtatgttttc acatgattat agagaaatta taatatatgt
    96961 accaaataat gtagacataa atgcatcaag tacaagttca tacttatttg tatatgataa
    97021 tgtagcttca aatactataa catataaaac ttcttatgga ggttttagta gagctataac
    97081 agagaacaaa gtaaatagat tagaaaacct aaacttaata tctaatagca atcttcactt
    97141 gtcaacaaaa tcaattttag gcgttaaaaa tgtaaacata gaatcagagt cattggatat
    97201 atcttcagag aatgaagatg tatttatcaa taatatagaa gagtatatac ctgaaaatgt
    97261 aaatataaaa gagaaaatag gtagaaattc aaattatgaa agtgaatttt acttgtactc
    97321 taatatgcca attgctaagt tcctggacat agaagttcca aattctaagg taagacttga
    97381 tataccagta aataagtata aatttaattg tgatataaag tcaaaagaag caattgaaga
    97441 atttaataat gatgaagaat atgacaatga ttcatatgat tatgaacata gtgaagaaca
    97501 tagcaacaag tatagaaata cgagggaaat aaaagggctt ttgaataaaa atctgtcgaa
    97561 tttagagaaa gaatatacta taaaaataaa ttcaaatagc ttagaattgt aaataattta
    97621 ctataataat ttataaattg atttaaaagt ataaaaatat aatctatact atggtataat
    97681 aagtatcgaa agagaattag gagagggata cttatgaata aaatagcagt aagtttttta
    97741 ataattgcta ctactttatt gagtacagca tgtatggatt atagcatcag tgcagttgag
    97801 ctagttgatt ctaaagaatc agcagttgta aagaaggatg aagatgcaaa agaagaaaca
    97861 actagtaaaa tgattaattc taaaaaaact actaaaatac ctatagagat aatttcaaag
    97921 gatgagaaaa tagtaaagta cttacagatt gatgaagaaa gttcacttaa ggataaactg
    97981 cgattaatct tagatacatt atcaaatgag tattttaatg gtttagacat ggaagtagaa
    98041 gttaaggaaa aagataatct tgttaaaata aacttgatag aaccagataa aaaaagtaga
    98101 gtttcttgga aagatgatta tttgaatgaa caaaatataa tatatactat aaataatatt
    98161 attaaaaatg tcatccaaga agaagataat agcatttgga ttgaagaagt agagatatac
    98221 tacaatggaa aattaataga attaagataa aaaaagatgt gtttttaaca catctttttt
    98281 ttgtttttta attcttataa aatccttata tttatgattt agaatgattc ttgtaaataa
    98341 gtttgacaaa agaaaggatg aaaattatga ataattatat tttgcaggta aaaggagttt
    98401 ctaaaaaatt taaggagcag atggcagttg ataatatttc actagcaatt aaatctaatt
    98461 ctatatatgg attattagga ccaaatggag ctgggaaatc tactttatta aaaatgataa
    98521 ctgggatttt aaatccaact tcaggaaaaa taatgtttga gggacataga tggactagaa
    98581 aggatttatc aaatattggt tctcttattg agtctcctgc tatatatgag aatttaacag
    98641 cacgagaaaa tttaaaagtc catactactt tacttggtct tcctgactct cgaattgaag
    98701 aagttttaga gactgtcgac ttaagagata cttttaaaaa gcgttcaggt caattctctc
    98761 taggtatgaa gcaacgtctt ggtattgcta ttgcattatt aaatcaccca aaacttttaa
    98821 tcttagacga gcctacaaat ggtcttgacc ctattggtat tgaagaactt agaaaattga
    98881 ttcgttcttt tccaaaacaa ggaattacag ttattttatc aagccatatc ttgtctgaag
    98941 ttgaacaagt cgtagatgaa atcggaataa tttctaatgg agtaattggt tatcaaggag
    99001 aagtatcaaa agaacaaaac ttagaaaaac tttttatgaa agttgtagct gaaaatagaa
    99061 agagagggga gtaatatgga aagatttatt agagtggaat ttcaaaagat gaaaggaact
    99121 tttggaatga agttgatatg gatagttcca gtgttttgta tacttttgtg tggactaggt
    99181 ggagggcaaa atgctgcttt caactggtgg tatacgacat ttcttccagg agcattaaca
    99241 ttaatatctt ctttaatagt attaaaagat gaaaaaagta aatatcgtgg tattttacca
    99301 ttgccaattg aaatgaaaga cgtttgggct ggaaaaatga tttactgtat tatttgttgt
    99361 tctatagcat cgattatttc tgcaataggt gtagtttttg ttgggataat ctataaagaa
    99421 actatttcaa taggtcaaaa tatcattgca actatattaa ttattttact atttatgtgg
    99481 cagattcctc tttgtatgtt tttagcttca aaatttggta tatttgttac agttctaaca
    99541 aatatgttct ttactattgt tggagttgct gttttctcaa ctacagaaat gtggtatgta
    99601 tttccatatt cgattccttc aagattaatg gttgttgtat tgcatattct accaaatggg
    99661 cttcctgtac cagaggggag tgaactttta aataatgctg ttattttacc aggagtatta
    99721 atatctgtta ttttatttgt attatttgct ttagttacaa gagcttggtt caataataga
    99781 gaggtgaagt aatatgagac aactaataag aatattttgt tctgatttaa taaaattaaa
    99841 gagaaatttt ataatactaa tgcacatttg cattgcttta atggggatgg gattgttttt
    99901 atggtattat aaggtttcag gagctgataa tatattaaag atagtagcat atttacaagt
    99961 tatagcaata gcttttcctt tattgtcagg tgttgtgtgt tcaatgtttg ttgaacaaga
   100021 atattatgca gggaattata aacatatgtt aacaacatct aatccaaaat atcttactct
   100081 tataagtaaa tatataatct tagtatgtct tggttttgta gcaacattag tgtctgtatt
   100141 aggttttaaa tttggtatat ctaaggctta ctttacatca agcttttata tgatttcaat
   100201 tctaatttta attgggtgta atttatttga atacatatta catttattct taagtttaag
   100261 gttcggaaaa ggaacatcaa ttggagtagg tatagttgaa atgttacttt cagcattatt
   100321 attaactgga ttgggttctg gcatttggca gtattttcct tgtgcatggg gtgttagatt
   100381 tataactatt tggtcgtctt tttcaagttc taaaacggtt gaatatataa aggttgaatc
   100441 aataaaagca tatcaatcaa caggtttaat gtgtggtttt gtaacaattt tagcatttgt
   100501 aattttatgt atttggtttt ctaaatggga aggtaaaaag tcagaagaat aaataaaaat
   100561 tgactgttta tttacattat atttatatta ttatgttaaa atataactta gcaatgaaaa
   100621 atataaaata atcaaataaa aactggttag gtattaatta tgaattaatt aaaatatttg
   100681 gaggatatgg cacaaatgct tagaagtaaa aaatctaaca acaaaaaagt tgaaaagtta
   100741 agaactattt ttataaaata tttatcttta ttctttgtta tgacaatttc atttgcactt
   100801 cttttaatgt tatcattttc tgtattatta tcatcaggtg taatattacc agctaattat
   100861 tcagaaaaac aatttgataa atataaagaa aagattattt caagtgaaaa agcaattgaa
   100921 gatataattc caaatttata cgagtatggt gtttatactt tagatgggaa tttgatctca
   100981 ggcactttta ataaaaaaga atcaaaacaa gtatggaatt taatgagaga tattgaagaa
   101041 aggcatgcat attcagaaag ttatataaag ttttttaaga aagatgaagt ttttataata
   101101 aaatacaaac tagtatcaga gtatagttct ccagttttaa gagcatattt accaaaacca
   101161 gagatgttag gtatgattat ttttagtata atatttttta ttgaaattgt tatattatca
   101221 aaagtatttg gcaagaaatt taatattgaa atggagcttt taaaaaatac tacagaaaaa
   101281 atagaacaac aggatttaga ttttgttgta gaatctagta aaatttatga aattaacaat
   101341 atcctttttt ctatggataa aatgaagttg gcgttaaaga attctttaga aaaacaatgg
   101401 atgctagaag aaaatagaaa ggaacagata tctgcactgg cacatgatat aaaaacacca
   101461 ttaacaatta tacatggaaa tactgactta ttaattgaaa taaatgaaaa tcctgagtta
   101521 ttagaataca tggaatatat ctcaaagggt gtcactcaaa tagaaaaata tattaatact
   101581 ttaatagata tatcaaaaac agagaatggc tatatattaa ataaagaagc aattaatatg
   101641 agtgagttta taaaagatgt cttactgcaa atagaagcat tagctagtac taaaaactta
   101701 gatgtggagt tttataaaca agataatttg cctaaaaata taactataga tagagaactg
   101761 ttattcagag ctattatgaa tataatttca aatgctatag attattcacc aagccagagt
   101821 aaactataca taagtgtatc agtaagtaat aaatacttaa aatttgtagt tacagattgt
   101881 ggaagtggtt tttctaaagc agatttgtca aaagctacag aacagtttta tacaggagat
   101941 ttgagtagaa attctaaatc tcattacgga atgggacttt atattgtaaa taatattgta
   102001 caaaaacata atggaatttt atatattgaa aattctgtga aaactggtgg tgctatggta
   102061 acaattgaaa taccaatagt ttagtaaata atatccattt tgtaaatacc taaattttat
   102121 gatttatagg tatttataaa atggatagtt tttttgattt tatatattag ttaaatctga
   102181 taaaaagttt tcaaacataa ctccatcatt tctatcagta tcaaattgag atgtgtaatt
   102241 tatagtttta tatataaaat ctgttgcagt attaaccgct actcccaaat catgtttatt
   102301 tactaacata ccacaaagta tagatgtgaa tatatctcca gttccactgt aagaacaatt
   102361 attgtatttg actgatgtaa agaatacatg gtcattatct ctatcataag ccaaatttaa
   102421 tatattatca tcttctaata taccagtaat aacgactttg ctaggtccca aatcagatac
   102481 agattttgca atatatataa gctcatctct attataatcg cttttagtat aatcatttcc
   102541 agttaagaaa caagcttctg ttaaattagg agtagttaaa tctgaatgtt taactaattc
   102601 tttaatttcc tgtctcattt cttctgtgaa tattggatac ataactccat tatcacccat
   102661 cacagggtca actacgataa aagcattggg ataatcattt ataaaattag ccactatctc
   102721 aatttgatgc tttgaaccca aaaaaccact atatatacta tcaaaattga cttttaaatt
   102781 tttccaaaca tttgaatatt ttaccatttc atcagtaaag tctaagaaag taaattcagg
   102841 ataaccagtt tgacttgaaa gtatggccgt tggaaatgga caacattgaa cctttaatgc
   102901 tgaaagtata ggtatagcaa ccgataatga gcattttcct attccagata agtcattaat
   102961 tgctgcgact tttttttgca taaaaaaccc tccattagta tgtattaatt ataatgatac
   103021 caaaatattt atatacatat atattactat aaaaaaaaga aaaaagtaga ttataaaata
   103081 aaaaattgta aaaaaaacag tgtattgata caattaattt ttaatattgg acataataaa
   103141 atagagaatt attaaatatg aaaattattg tatatgacag aatcttcttt gtaatttcat
   103201 ttataaggtg tactatttgg gaggtgtagc tttgaaaata ctgaaaaata agaataagta
   103261 catcaaaggt ataatggcat ttgtattttt gtctttagct actacagcag gtgtattttt
   103321 aatcaatgat ttaagtatga aaaatatgga agaaaaagtc atggaatctg caaatgttga
   103381 aggtgatgat gtaaaagacc aatataaact attgcttgaa aacttatttg actacagaaa
   103441 taaggcaata ttagagaaaa atgaaaacat tttaaaaggt ctttatgaga cggataaaaa
   103501 atttggtctg tgggcttatg aaaatgaagt aaaaaagatg aagtatttag aaaactggtc
   103561 tagtaagcaa ggtgtaaaat ttaaagacat aaagacaagg gttaagatta aaaaaataaa
   103621 agaaaaagaa aaagacctct atggtataat ctgttcagta tcgactgaat ataagtattc
   103681 atatgaaaat caaaaggaca aagaaaatgc ctttagaata ggtacatatc attatctaaa
   103741 tgtaaaaatt atagataatc aatatgtcat aactaaagag tggtacacag acccttttgc
   103801 agactcttta aatttagaaa atataaaatc tgaggatata agaaactata ttgggcaaca
   103861 agatggtgta gagttacagc ttacagatga acaaaaaaag gctatagatt atgcacataa
   103921 atactgtgga gccgcagctg atgaagaaca tggtatgaaa tttaatccaa actataggga
   103981 ttataatcca gaaggtggag attgtgcaaa ctttgcatca cagataatgt ttgaaagtgg
   104041 aaggttcaaa aagaactcaa tttggaatta tagcgagaga gcaggtacaa aagcatgggt
   104101 aaatgcacaa gcttttaaaa attatgcact gtatagtgga agaggttcat taattgctaa
   104161 aggttcctat gaagaagtat acaaagaagc ttataattta cgtccggggg attttgttgg
   104221 ttatgagaag aaaggcagaa taacacatgt ttcgacagtg acaggattag actcaagagg
   104281 atatcctttg gtaacttgcc ataatactga tagaatgttg gtgccatggg atttaggctg
   104341 gagtgataag tccataagat tccatataat aaaaataaat tattaaaaaa ttataaagaa
   104401 aaataaagtg taaaagataa taatcattta aaattataaa gtaaaaaaat tgattattaa
   104461 tgtataaaaa taataataat tgacaaacat agctatatat gatagagtag taataaggtt
   104521 acagaaaaga gtagctaaat atttgtgttt ttttaggagg atttattaat gaaaactggt
   104581 gtagttaaat ggtttaacaa cgaaaaagga tttggattca tatctgtaga aggtgaagga
   104641 gatgttttcg tacatttctc agctataact ggagatggat acaaaacatt agaagaagga
   104701 caaagcgttg agttcgaagt agtagatgga gctaaaggtc ctcaagctgc taacgtagtt
   104761 agattataat taaaaattca tatatattag tgttctagta atatgagaga taagccgcta
   104821 atcatttagc ggttttttca gtttttgtaa ataaaattaa tagcaaaata aattaaaatt
   104881 attaaaataa aatcattaat aatgagataa atatgttaaa attaatagtg tagagtaaaa
   104941 ttattatggc taagtttaag tcaattaatt tttagtaaat tttctaaaaa gagaataagt
   105001 gatactgata gaccatataa aaatattaat aaagcataat aagattaaaa tgagcaaagg
   105061 aaaaacgctt gttacagcgt atagtattaa gaatacttag aaaataagaa aggagaaagt
   105121 tactgcaaaa aagtaacatt ataaatattg agtaatattt ataagttttc agtaacggtg
   105181 ggtagtgtaa tgaacatatt attctttcta acaccaaaaa gtgaagtagc atatatatat
   105241 gaagactaca ctataaggca agcactagaa aaaatggaat atcacaaata ctctgcaatt
   105301 ccaataataa gtaaggatgg taaatatgtt ggaactataa cagaaggtga ttttttatgg
   105361 acattaaaaa acgatttaaa tctggactta aagggattgg aagatgttcc agtgacagat
   105421 ataaatagaa aaatggataa ttctcctgtt tccatcaacg cagatattga agatttagtt
   105481 ataaaatctt taaatcaaaa tttcattcct gttatagatg accaagacac atttattggg
   105541 ataataaaaa gaagagatgt aataggttac tgttatgaga taatacgtgg atataaaaat
   105601 ttagctaatg ataattaaaa atcttattta aacttttaag ctgagttctt tacaataaaa
   105661 gaatgataat atgaaactga atatttaaac tttaatataa aaagctgtct tttctaataa
   105721 atattgtgaa aagacagctt ttttatatat gaccttatga ttaatcgttg tattttacaa
   105781 ggtttccgta cttagcatta agagcattta tcttatttcc ataaacttca ttttgttttt
   105841 gatataataa acttttttca acttcagcct taacttcatc aaatgtagac tctgtacttt
   105901 cttgaaggtc ttctaatttt attatatggt atccaaattg agttttaact ggttcactta
   105961 cttcaccttt agccatagag aacacagctt cttcaaattc aggaaccatt tgtcctctac
   106021 cgaatgttcc taaatcacca cccatatctt tagatgggca agaagaatgt ttaagagctg
   106081 catcttcaaa agatatttct tctgatttta tttgagcaag tatttcttta gctttttcat
   106141 cactatctac taatatatgt ttagcagttg cactttctgg tttagagaaa gagctcttat
   106201 tagcttcaaa gaattttact ttttcatctt ctgttacatt aacactagat aaaactttat
   106261 ttatagcaaa ttgctttaat acattttctt ctatcttttt catttctaat ttaaatattt
   106321 cttcttcatc taatttttct tctttagcat ctaagaagaa taattcttga ttcactaaat
   106381 catttaataa gtgttttttt ccttcttcag ttttaaattg catagcttga taagggtcta
   106441 atgattttaa tgcattttca atatcaatat tagttatctc tttttctcca actgttgcta
   106501 aaactttttt ttccataata gttaactcct tcatagtgta tttcattatt aatataagac
   106561 taccatctta aataatatca gaaaataatg tagatgtcta atatttaaag ccatattaag
   106621 tcaaatagaa ttaaatttag tagaacaaag ttattacaat taataaaagt gagctcataa
   106681 tacccactac accttcatca tctttaaatt taagagtttt tactattgaa taataaaggt
   106741 atattccagt aaaaataatc tttaaataca agaaaaataa actctttggg tatattaaaa
   106801 agctaaaaag tgtaaatata aaagcaagta gagtacttat cctgtaaaag aaatctattt
   106861 gtgtaatgtc tttatatttt atcataaaca ccgaatataa aatgatgaaa ataattgcga
   106921 cgattgcata tatggtaaat aacatatttt caagagtacc atttgaaatt actatccact
   106981 tataccacat aattggccaa aataatagtg ctaagaactt aaaataatta tcaaacaact
   107041 tttctttata cattcatcaa acaacctttc ttaacaaaag catatatttg tttttagaat
   107101 tttaaataat atgatatcat tattatatat taatattgaa tttatagaaa ccaaaatttg
   107161 ttaaaataaa tatatagatt ttactgttaa gccagttaaa attactacta tttttattat
   107221 gaaattggat caaatatgta gaaatacggc aaattagtta atattaaata tttattattt
   107281 ccaagttgta aagactgttt ttttaatgat aaaaattcta atcttttttg aaagaaagta
   107341 atatccacat taagtatgtc tgccatttca taaacgcaag tgatgccaga attaattatg
   107401 tttattatat cttcttcagt aattaagaac tcacaagccc attttaaggc tttattttcg
   107461 cacttatcta taataatttt tgtataataa tcgttataag aggatacata gtatccaagg
   107521 ctagtgaaat gatgtccaag ttcttcagct aagatggatg tcaatttttt tgagttttgt
   107581 tttaaattac tgagtaatga tataatttta ataccatgtt tgtttatata tagcccttct
   107641 aaatcacctg caatataagt ggtataatga attattatct cttcttgaga agctaattca
   107701 aaaagcttat ccaaattatt cataaaaatc cccctaaaat agaatgtatg tttgccttta
   107761 aattatatta aaagagcaga aaaatagact gctcatcata tggtttattt ttttttatat
   107821 ttatttagta aaaattctat ataatcatta agttgttctt gtgcttcttc aggtaactct
   107881 tcatgtggat tttttctatg tgcagctact gtatcaatat tttccttaac taaggttctt
   107941 ccaagaaggt aatcaactga tacattaaat acatcagcca atttgtttaa aatgtgttca
   108001 tcaggaaatc tgttttctgt ttcatagtac cctaagactc tttgggaaac gcctactttt
   108061 tctccaagtt ctctttgagt caatccaaat tcctttctaa gttctcttaa tcttttggca
   108121 aacattataa caccacctta tgtatagatt ataacaaatt gttctaaaaa ataaaactaa
   108181 taaaatataa aagaatattt ttttctaaaa tctattgata aagaacaaat gattctatat
   108241 aatctaagtg tggaagaaca aaatattctt aatggtaatg gaggtataaa acaatgttta
   108301 aaaataactt gaaatattat agaaaatgca aaggtatgac acaaattcaa cttgccagaa
   108361 aggctggaat tacaaatgac tatatatctc aaatagaaag aggtataaaa aatcctggtc
   108421 ttcttatggc taagaagatt tctagtattt tagaacaaaa tatagaagaa gtttttttta
   108481 tacagttata gaacaatatg ttcttgaaag ttgtgagatt agtaaaaaac tgtgcactaa
   108541 agagattatt gtaaatttga agctaataat aagtatataa aaaaggagaa gtactatgga
   108601 aaacaaaaaa gatatattat ttaaagaaac agatgaaaga ttacataatt ataagtattt
   108661 ggatataaag ataaagaata ttaatttgga cataaaaaga tgtgagaatg aatactctgg
   108721 atgtggagca atggtatata cagaaaagac tagtaacaca tataacataa gttcttctgt
   108781 ggaaaatgag gtgttaaaaa gagaggaaag attaagaaaa ttaaaaatgg aaaaagaaga
   108841 tatagaaata gaaaaagaga agatagaaaa tgctctaaca tgtctaaatg atatagaaat
   108901 ggaatttttt aatctttttt ataatagtaa gacaaaaaac aatatgacat atatttctat
   108961 gaaactacac ttagatagaa catcttgcta caatttaaag aaaaaaatga tatttaaatt
   109021 gagtgagata ttataaaaaa tatgacaact ttacaacact ttatatacac tattgcaaca
   109081 ctaggcaata aaatatgtga gataatgtta ttgtgaaaga aatccatatt gaaggaggtg
   109141 ataaattgaa aagaataata ttacctaaaa atatagaaga tatttgacag gaataaatga
   109201 gatgtatatt taaaaatgac ttatatcatt tatagtaaga ttatcagatt aagcaagaat
   109261 atttagtgat agtgtggtga ttatttgctt aaatacaagg aaatattaga aacaattatt
   109321 gagattctca aaaaaaactt tactgaaagt atttttattg atgatgaaag tgtgcaaggc
   109381 tctgaagggt cttgtttttt tgtaagtata ctatcagtta tttgtacacc tataatgtta
   109441 aatacgaata ataaagatat tgttatctct ataaaatact taccaaaacc acagtcaaag
   109501 agtattagaa tgtatgaaat ttcagatgaa ttaaataagt tattcaacag aaatataaag
   109561 gtaacagaca gaaaattaaa tataacaaag ctagaacaaa gtattaaaaa agaagagtca
   109621 atttatgtat tgaactttac aattacacta aattatctgg atagtgtata tgaagaagat
   109681 gtagtatatg aaaatatgga agaaatcaat ttaaatttag gagagtgata gtatggctat
   109741 aggattacca agtatcaaca tatcatttaa ggagctagct acaactgtta aagaacgttc
   109801 agctagagga ataattgcaa tggtgcttaa agatgctaag gcactaggtc ttaatgaaat
   109861 acatgaaaaa gaggatatac cagttgattt atctgctgaa aataaagagt atataaattt
   109921 agctttgatg ggaaatgtta acactccaaa taaattatta gtttatgtaa tagaaggaga
   109981 agcagatatt caaactgcat tagatttttt agagactaag gaatttaatt atctatgtat
   110041 gccaaaagca gtagaagctg ataagactgc tataaaaaat tggataatta aacttagaga
   110101 tatagataag gttaaggtta aagctgtatt aggaaaagtt gtaggaaatc atgaagggat
   110161 aattaatttt actacagaag atgtgttagt tggagaaaag aaatacagtg ttgatgagtt
   110221 tacaagtagg gtggctggac ttatagcagg aacaccttta agtcaatcag taacttatac
   110281 taagcttagt gatgtagttg atatacctaa gatgacgaaa gttgatgcag aatcaagggt
   110341 taataaagga gagcttatac ttattaagga agcaggggct ataagaattg caagaggagt
   110401 aaattcttta actgagttaa cagaagaaaa aggagaaatg ttccagaaaa taaaaatagt
   110461 tgacacttta gatattatac atagtgacat aagaaaggtg ataatagatg actatatagg
   110521 aaaggttact aacagttatg acaacaaatg tttattgata gtagctataa aaagttattt
   110581 agaagaatta gaaaagtcag cacttataga atctgattct actgttgaaa tagattttga
   110641 agcacaaaaa tcgtatttaa aatcaaaagg agtagattta tcttatatga cattacaaga
   110701 aataaaagaa gctaacacag gttctaaagt atttttaaaa gcaaaaataa aagtacttga
   110761 tgctatggaa gatatagatt tatcaataga aatataggag gattattaat atggcaaata
   110821 tggaagctag aaatgtaatg agtggtactt ggggagaact ttggcttgat ggaaacaaag
   110881 tagcagaagt aaagaagttt caagcaaaga tggaatttac aaaagaggat attataatag
   110941 caggtcaaat gggtactgat acaaagtata tgggatataa aggaaaaggt tcaataactc
   111001 tataccatgt tagttcaaga atgcacaagt taattggaga aaagataaag agaggttctg
   111061 aacctagatt tgttgctata tctaaattaa atgacccaga ttcttatgga gcagaaagaa
   111121 tagcagtaaa aaatatagca tttgatgatt taactttagc tgattgggag gttggagtaa
   111181 aaggagagat agaagcacct ttcacattta ctgagtatga ttttcttgat ataatttagt
   111241 tttatatttg gttttatact gatatttagt agatatatac ttaataaatt taggtagtta
   111301 ataagtaaaa aagttagttg attgaatttg attgataaag gagcaaataa taatgaatga
   111361 aaatggatta tcaaaaaata taaacatagt agatttactt ttaaatgcag atacagaaaa
   111421 cttagaaaga ccaagtacta tagttgaact taagagatta tcaactatat ttgggcagga
   111481 atttaaagta atgtgtagag ctttaacaat aagtaaagat gaagagatac aaaatacttg
   111541 tcttaaaatt gatgaaaata tgaaaacgga tatagactta ccggagatgc agatgcttac
   111601 aattatagaa ggtgtttgtg atttggatgg aaagctttta tttaaaaata aggaactaat
   111661 ggataaattt aaggctccaa caccaaaaga attggcaaga aaactattat taccaggtga
   111721 aattaccaac ctatatagaa tacttcaaga tgttatgggt tatggtaaaa atgcagtgat
   111781 agaagaggta aaaaactaat agggacggat accaagacta caataatgta ctattattgg
   111841 aagaaaaaag gtataagacc gtcccttttt tatgcaatgg ataaaggcga attaaagctt
   111901 attgaagctt ttttcgcctt agaaattgag gaagaagttg aaaaaatgaa acatggatat
   111961 ggagtgtgtc ctttgacagg aggtggtatg taatgggaaa tgtgagagaa gaaggtataa
   112021 atatgtatct tacagataat tacacaccaa aaatgaacca aattatatca gtaactgata
   112081 attttaggag agcaactgtg gctgtttcac tttccactaa tgtaatggct agtagcataa
   112141 aaaattctat tggaagtgca agtagtagag taaacagttt aaattcctcg ttaagaaaag
   112201 ttcaaactac tgctagtagt gtaagttcaa ctatggcaaa attaagttct agcataaatg
   112261 ctgtttcagg agttattgga agtttaaatg gaagtattat gagactagca ataactatag
   112321 ctatgattat tgattatttt aataagttga ttcaaaagaa aaatgagttt aattcaaata
   112381 ttatgattat attaatattt aaagctaaaa gtgatgaagt agaaaaaact aaaaataaat
   112441 tacttggaaa tttaaaaaag attggtggca agatttggaa tatcgtaata aaagcaaaag
   112501 atatgactaa gagagtgata agtagtatct tgggaaaatt aaaacgagta gagaaacgtc
   112561 cttatcaagg aagtattaat cttaaagata tggtaagtag tgctatggct agaattttgc
   112621 ctaagttaat gttgtttaaa aatacttttt ggagtggtgt aatagctata aaagatatgg
   112681 caagtagcat tataagtaaa gtatttccca aattgagatt gtttgcaggt aaggtatgga
   112741 gtggtgcaat agctgtaaag gatatggcaa gtggaatact tggttcgata aaagggaaga
   112801 tatctgattt gacaaatggt gctactatag gtgtcgctgt gaaaaagggt gttgacttac
   112861 ttggtcagga acaaaatcag aaagttgttc tagaaagtgt aatgaaaaga aatactggaa
   112921 aaactagcca aaaagatgtt gataagtatt atgacagttt agtaaatatg gcaaatgata
   112981 cgccttttga ccctgaagat gttgttgcaa tgggaactaa agctaaaatg attagtaata
   113041 ttactggtgg caaaaaagaa aaagatataa ctcaagctat ggtagatgtt agagctttaa
   113101 atatgaatac aagtagtgaa caagatgtat cagcagcttt cttaagtgca gcaaaaggaa
   113161 atatggaatc tcttaatact ctggtaggag aaaattataa aacttttgat gaagcattgg
   113221 aaggcataag tgtaaagcag atggggttag ctaaagaaat gagtaataca ataccaggta
   113281 taatatcagg agctcaaaca agcattaaca atggtttgaa gagtattgtt aaaccttttg
   113341 atgatatttt aggtcaagga ctaaagaaaa taaaaacttt tatagaaagt ggattaggga
   113401 atttagctgg cttatctgaa aaaatggctg gtaaaatagg caatgtaatg aatggtaaga
   113461 taattattgg caacaaatat gaccagatgc aatctagaag tgtaaaaaat ggaaaagagt
   113521 tttctgattc tactcaatat cgaatttcta atgaggctga aaagcgtaaa atgatggttg
   113581 aaaataagca agaacgtttt gaaaatcatg cagcaacaat gatagggaat gcaccaaaag
   113641 caattgttaa cgcaggaagt acactattac aaaatattga ttttacagca ttaatagatt
   113701 cactacttcc agtagtaaac ttagtaaata atttactaga tagtataaac aataaatcac
   113761 caattgcaca aggattaata agtatatttg gtacaatagt aactacagca ttccaactaa
   113821 tcggacctgt agttgaagct gttagtccta ttatcacaag aatttttact tttttaggtg
   113881 aatatgcacc tcaaataaac aattttatag agacactggg tgttatttgg aaaactgtat
   113941 gggagacctt aggacctctg ttggaaactg gatggaaaat tatagagcca atattgggag
   114001 ctttttttaa catattagat aaagtatgta aaatagttaa agatatatgc aaatggtggc
   114061 aaactatgat taataagata aaaaatggaa gcatcacagg aacagtttta aatctagtgg
   114121 aaaagagtaa aaaaaattac aaagataatc catatgctgg aacaaaggct ggtgattctg
   114181 gtaaagctta ttcaagtaag aaaggtaata atgcatttgg attgaactat gttccttata
   114241 atgactatca aaccagactc catgaaggtg aaatggtttt aactaaacaa gaagcaaatc
   114301 aatatagaag cagaaaaaat ggtggaaata taaacatagc taagttagct gatacaatag
   114361 tgattagaga agaagctgat atagaaaaga taacatcaaa attagttgca agtatccaat
   114421 tggcacagtt agggggtgtc ttataatgga aatgtggctt agacaagcag aagatagatt
   114481 tagatttcca gtatttccat cttcctttag tattaatgga aaagctgctg taaactcttc
   114541 tagtatactc aaaataggtg aagtagcaac ttttggtggt gtagctctta aaagcatttc
   114601 aatatcaagt ttttttccaa ataaagacta cactttctgt gactatacag gttttccatc
   114661 accatatgat tgtgtaaata agatagaaaa atggatgaag gaaggtttta tattaagatt
   114721 tacaattacg gaaacaaata taaatatgga agtcataatt gaagggttta gttatgaaga
   114781 aagagatggg actcgagatg tatattttac attagattta aaagagtata aaagaataaa
   114841 gataccaaaa gtaactccaa aacaataact attatagata ataagttgta agtaactgct
   114901 gatagaatta aatgaaaagg caggtgattt tttattatta agatttgggt acacataaaa
   114961 aacggaagta tatatgacat aactgacata gtagacaagg tatcatggtc aggtgattat
   115021 aaatctccat caaggacact agagttttca ataatacaat catcatttga tgtaaatttc
   115081 caacaaatcg atataccaat agctagtaca gtctgtttct atgtagatga gaaagaactc
   115141 tttagaggaa tgataattaa taggtctaaa gattcaagca gtaatgaaat tagttttgta
   115201 tctaaagata tgggattttt acttacacaa agtgaagtgt catacaattt taaagataag
   115261 ttagttgaag acatagcaaa gcaagtattt gctgaaaata ggctttcagt tggaacaata
   115321 gcaaagacca atgtcaagta tacaaagatg tttataggag taaatggtta tgacacaata
   115381 atgagtgcat atacagaggc aagtaaaaag acaaagaaaa agtatatgat agaggctaat
   115441 ttagataagt ttaatgttat tgaaaaagga actgttacat taagtgttat gtttgaagag
   115501 ggatttaata ttataaatac caccttttcg gagagcatgg aaaatgtaaa aaataaagta
   115561 atagtggtag accagtatgg aagcaagatt agcgaaaaaa tagataatga aatttttaag
   115621 gaagtaaatg taataatgca aaaagtaatt cagcaacaag aaaatcaaga tgtagatatt
   115681 gatagcgagt ttaatgggat agaaaaaagc tgttctctta aaggttatgg agatgtaagt
   115741 tgtataactg gtagaggagt aaaagttaaa gattcttata caaagcttgt aggactattt
   115801 tatatagata cagacaaaca tacttggcaa aatggagaat atcaaattga gcttgaactt
   115861 aattttcaaa atcttatgga tgaaaagtca gcaggacagg atgaacctaa ggaagaaagt
   115921 aatttagggg gagaagatta tgcaggagga aaagagttta cagcagaatt tacagcttac
   115981 tgtcctagaa aagaagaagg tggagataca gattgtagaa agaaaaaact tgacccatct
   116041 aaaaaaactt gcgctgctcc tatggttggt aaatatgagc aaacttatta tacaaaagag
   116101 tttttaaata aacatccttt attgaactat ggagatgaaa tacaggtaat tacaggagtt
   116161 tctggtcgtg atggagtcta taaagtaaat gacgtaggac ctgcaataac tatagaaaaa
   116221 aatggaacat accatataga tattttattt ggaaatgttg aagaagctag taaatttgga
   116281 agaagaaaag gaaaaattat tattggtggt tattctggta atgtatctga taaagctaaa
   116341 atagtaatat cagaggcaaa aaaacatcta ggtaaacctt ataaatgggg tggaaatgga
   116401 ccaagtagtt ttgactgttc tggtttaatg gtctactgtt ttaaaaaagt taatgttagt
   116461 ttgccaagaa cgtcaaatca acaatctaaa aaaggcaaga aagtagaaca aaaaaatctt
   116521 caagcaggag atttagtatt ttttcataat ccagtcagcc atgttggatt atatataggt
   116581 aatggagaat ttttacatgc tccacaaaaa ggtgatgtag ttaaaataag taagttaagt
   116641 agtagaagag attttaatac agctaggaga gtattataaa aggatggtga tataatggct
   116701 aatccaataa atgaatttat aggaataata agagaagaag gaaagtatca taatcaacct
   116761 tcttttttta ttggaaaaat taaaagtaaa ttaccagatt taaaaataga gacaaataac
   116821 atcatattag aaaaagaaga tattttgata gatagttgga tgattgatag acagctagaa
   116881 acatttgaca cagaaacaaa tcaagaacac cagcatgaag taaaaaatcc ttttatagat
   116941 aactttgaat ctggggatat ggtaataatg tttagaatag gcgaaaaatt tgctgttgta
   117001 agtaagttgg tgagcttata atgagtacaa tatttccttt tataggtgtc ccagaggatt
   117061 atatcttacc taaaacagaa gaattgccaa tctttcgtga agtggcatgg gattttgaaa
   117121 aagatgaacc tattttagaa aaaggtgact ttaaaataat tgaaaaaaaa gaagccttaa
   117181 aagtttggat atacaagtgt ataaagacaa atagatatga acatgagata tactctttag
   117241 aatatgggac agagctttca gaactaatag gacaaaaata tacaaaaggt cttacagaaa
   117301 gtgaagctag tagattcata aaagaggccc ttctaataaa tccatatata ttagaagtaa
   117361 acgtaaaaag tgctaacttt aacagagacg tattgagtgc aaatgtaaaa gtatccacta
   117421 tctatgggga ggtggaaata aatgtatagt gaccagacat atgaagtaat aaaaaataga
   117481 actcttgaaa atattaatct tgatatttat aaaggagaag gttcttttct aaacaacatg
   117541 gtatctggaa ataatctaga actttcgaag atatatctag aactttcaaa gatacataaa
   117601 atggctttta tacaagacac atataaccag tttcttgata aaagagtcaa tgaatttggt
   117661 gtatatagaa agttaggtac agagtcaaat ggagaagttg aatttattgg agagaaagga
   117721 actgtaataa ataatggcac aataatatca tatagagatt tactatttgt agtaataaaa
   117781 gatgtaacta ttggtagtga agaaggtgac aatagcccag ttcaagctct ggaagttggt
   117841 aagaaatata atttacctac aaattgtgaa tttaaactag ttgataatat atctggagta
   117901 acaaagatta ctaacacaag aagttttgaa ggtggtacag atatagagac agatgaagaa
   117961 ctaaaagaaa gattttataa aatccaaaga aatcaagcta caagtggaaa taaagctcac
   118021 tatgaagaat gggctttgga agtagatgga gtctataatg ttaaggttta tccaagatgg
   118081 gatggtccag gaacagttaa ggtcttgata tttggggaaa ataatcaagc tgttgataca
   118141 gaaacgattg aaaggtgtca gcaacatata gatgaagaga agcctattgg accaactata
   118201 acagttgtga caccattacc aatagaaata agtataagtg cagtaatgaa actagaagat
   118261 ggatatacat tagacaatgt aaaagaatct ttcctagaaa gtataaatac atactttaga
   118321 gatattagag gagagataat ctatacaaaa gtcatgggaa tacttataaa tactactggt
   118381 gtacacgatt taagtaatct acttataaat ggaagtacag ataatataac tattaatgaa
   118441 gataaaatac ctagtgtaac aactgttaat tttagtgagg tggaaaatca atgaagctaa
   118501 ttgataaact accatcattt gatagaaatt acattgtaga ggagatacaa ggtgcatacg
   118561 atacagaatt aaatattctt aaagaagata ttgatgatac ctttaaccaa ttatttgttg
   118621 atacagcgac atggggatta gatatgtggg aagacatact ctgcattgaa aaaaaagaac
   118681 ttgattttga cacaagacgt agcaatataa aagctaaaat gagaagcaga ggtactagta
   118741 ctattgaagt tataaaaagt atatgtgagg catatacaaa atcagaaaca gatataaaag
   118801 tttatagtga tgaatttaca ttcgtattga gttttatagc aaataactgt gactataaaa
   118861 ctcttttaga ttgtagcgag atgattgaaa gagtaaaacc tgctcactta ttacactatt
   118921 tagaaccaat aatactagat aaaagtatgg tctattgtgg tggaggtatg gtatgtagtg
   118981 aagaggtaaa agttcatcca tactttgaac caattataaa atgtagtgct gttgtaaact
   119041 gtggagctgg aatgttaagt agagaagaaa taaaggttta tcctttaagc attaaatgca
   119101 ttgaaaataa ttgtaagatt aatatagcta ttgcaaatga tacaggcgta gaaaatgtag
   119161 tagtttatcc taaatcggag gtggtataat tggaagaaaa attttatata atattaacca
   119221 aaattggtag agaaaaaata gcaaatgcaa ctgcactagg agagcttgtt ggattaacca
   119281 agtttcaagt tggagatagt aatggagaat attatgagcc aacagaggaa caaactgctt
   119341 taaagaatgt agtttgggaa ggaaatataa attctctaag aattgatgaa aaaaatccta
   119401 attggatagt tatagagact attttaccag gaacagttgg tggatttatg ataagagaag
   119461 ctgctgttct ggataatgag aataatataa tagctatagg taagtatcca gagacgtata
   119521 agccacgtgc tgaagatggc agtattaaag atttggttgt aaaaatgatt ttacaattgt
   119581 ccaatacttc aaatgttaca ttagaagtag acccgacgtt ggtttttgta actcaaaagg
   119641 atattcaaga tttagatgat aagtttgata aaaatataaa agaaataaaa gtaaaaattg
   119701 gagatacaga tatattaact acagattcta aagatttatc aggagctata aatgaggtag
   119761 ttaaaaaaat agaaaatata tcttttgatg atgttataag tggtcaaata caaactgata
   119821 tatcagtatt aaaaaatagc tataacaaat tatctgaaaa agtgctagat atattaatat
   119881 acctagaatt agagtcagaa gtaactgtag atgaggctgg ttattggtat gatacattag
   119941 caaatggaaa taacatagta gctatagaag ggcttaagtt agatttaaat agaaaatgta
   120001 taacaggtga aattggtaat gtgattttta gagatgtagt attaccattt agtgcaaata
   120061 gagttagata tatacatgat atggataata actttgttga gacaaaatct agtaacactt
   120121 atttaaaaga acaaaaagat ataactctaa gtaaatattc atatgaaata agataaataa
   120181 aggaggtagt actaataatg aagcaaaata aacttttaca gcgtggtgct tattttaatg
   120241 ataagaacat attgattgat gattttgata aaagatataa tgattatgat tttgtagaat
   120301 tttttactgg tataagtaat agtacctttg gtttaaaatc agatggtaat ttatatgctt
   120361 gtggcgataa tacaggtttt caactaggac ttggaaaaga ttcgtcagag agaaggatgt
   120421 ttagtaaagt aaaaattgat aatgtaaaat atgtatcttg tggttcaaaa cacagtgtag
   120481 cagtaactaa agatggattt gcatatggag caggaacaag taatgtaggt caattaggtg
   120541 taattgagtc tacagtatat tatgaattta ctaagctacc aatagatgat gtaaaaactg
   120601 ttgcatgtgg ttatgacttt acatttgtgc ttaaaaatga tggaacatta tattcagcag
   120661 gtttaaactc aagtggtcaa cttggactag gtgatactaa caatagagct acttttacta
   120721 aagtaaatat agatagtgtg aaagatgtag tgacttataa tcaatctgta tttatcataa
   120781 aaatggatgg gacagcacat gcatgtggat taaattcaaa tgggcagttg ggaattaata
   120841 gtactttaaa taaaagtgta tttaataaaa tagaaggtat ggataatgta aaacagatag
   120901 cgtgtggtag tagtcataca attcttatta agaatgatgg aactatgtat actacaggct
   120961 ataatggagt tggtcagctt ggtacaggaa ataataataa ttcaattgta tttactcttt
   121021 ctagtataaa taatgttaag tatgcttctt gtggaaataa tcatactatg atattaaaat
   121081 acgataatac actgtttagt acaggacaaa acaattatgg tcaactagcc aatgccaata
   121141 aagatgtagc atcaagaaat acttttgcta aggttaatgt agaaaatata aaagatatta
   121201 aatgtggttc tcaatttaat tttttaataa atggttcaaa agagatattt gtatctggct
   121261 gtaatttagc aggtcaactt ggttcatttt ttcatacaac ttttctgtat gagttttcaa
   121321 atgtgcaatc ttcaaattta gataattatt caggtttatt ggttaatgat gattatttat
   121381 atgttacaaa ggacaatagt gaatttttaa atgtaaagtt aagtgataat tttcaagatt
   121441 ataagaagat agagttaaca gatagcaata tgtttattgt tatgaatgat ggtacattgt
   121501 atgcttgtgg tttaaataat tatggacagt taggattggg agatactgtt aacaggtcag
   121561 ttatgactaa ggtggatata gataatgttt tggatataaa aggaaacgga aactcaactt
   121621 ttgtgcttaa gaataatgga acattatatt catgtggttt aaatagtaat ggacaattgg
   121681 gtttaagaga tgaagttaat agaaatatat ttacaaaaat agaaatagag aatgtaaagg
   121741 atttttgtgt aggaagcaat tatgtcatag ctttaaatca ctcaaaagaa gtatatggat
   121801 ggggaaataa tccttataat aatatagaaa aaacttctaa ttatccatat aagcagggaa
   121861 taagtaatat tgaaaagata gcagcatatg attattctgt atatatgata aacagtgaag
   121921 ggaaactata tgtttctgga tacaattata attatcaatt aggtaaagga aataatagta
   121981 accaaagcaa agcattagta tctcaatgta gaacaaattc aacatcttct acatcaaatg
   122041 gacttagaac gttacctaaa ataactaatg tttttccttt ttatgatggt tgtgcaataa
   122101 ttgacgaagg aggttatgtt tatttaacag gatatcatgg atatttaaga acattaaata
   122161 gcagtccaag tatatctgat tattcaagat atggaacttt tattgaggct acaaattcaa
   122221 atcataatac ttattttata caagagactg attttagtgg aattgaaaaa gtaataggga
   122281 tgtcaaataa tatattattt tttaagaaag gaagttcata tattactgga tatccaaaaa
   122341 catttggctc aaccattact ggacatagaa gttatactag tattaattct gagagttcta
   122401 atttaggaag taattttata atatatcata gtaattccaa gttatatgga aaagggattg
   122461 ctaatagtgg gcaatttggg aattcaacaa atatagatgg cacaagtaac tatgatacag
   122521 gattaaaaga cataaaagat ataattgtaa aaggaaatac tgtagtagta gtagataaaa
   122581 ataacaatat atatgtaaca ggaatgaatc agaataacaa acttgggata ggggaatata
   122641 acaacgaacc agtaaaaaaa ttcacaaata taactgaaca atcaaactca tttatattta
   122701 tggatgatat aaaagaaatt acaacatcaa gaaatacaat gtttatagta aaaaatgatg
   122761 gaacagccta tgccacagga aataatagtt ctggacaatt aggattaggt gacacaataa
   122821 atagaaataa gttcactcag ataaaccttg ataatataaa gaaaatatca acaagtatag
   122881 atggtaacac aacatttgca attagaaatg atggaacact atactccaca ggattaaata
   122941 ccaaaggaca actgggatta ggtgatatag taaatagaaa tacatttacc aaagtaaaca
   123001 tccaaaatgt aagagatgtt gttttaggga ctactcactc gcatgcaatc aaagatgata
   123061 acacattata ttcatgtgga gaaaacactc atgggcaact gggcttagga agcgaaagca
   123121 accatccaga cgtattgaca tttactgtaa acaatataac taatgtaaga gatgtgtact
   123181 gctcagatac aacaacattt attgtaaagg acacaaacat tgcatattgt tgtggataca
   123241 ataataattc acaactaggt atgggaaata ctactgacca gtatagtttt ataaagtgta
   123301 tggaaaatgt aaaagaagtt ataccaaatg aaataaatac ctatataata acaatctata
   123361 atactgcata tagtacaggt ttaaatactg attattgctt aggtctaaat agtaatagca
   123421 atcaaagttc attttctgaa attccaattt caaatgtagt aaaagtagct ccaaacagaa
   123481 ataatgcagt acttttactt acaagtgaag gggatgtata tactgcaggc aaatgtagta
   123541 atggttcagg tacaggaagt gagactccag agaagattaa aaaaatagca tcaaaggcaa
   123601 aggatattgg aatgaattat agatgtggac attatgtaag tgataatgga gacctatatg
   123661 gtacaggttt taataataat ggacaattag gtgttggtga tgtaacaaaa agagatacat
   123721 ttataaaaac caatacaaga gtaaagaaaa tacttccttt agaatatgca aatatagcaa
   123781 taaaagatac taatgatata tatatttgtg gattaaataa ctatggacaa ttaggtgttg
   123841 gaaatagata cgatagtaga aataatgata atagaatatt taattataag catatgaatt
   123901 ttgtaatggg tgatttgaca tctattaaaa acagacataa ctttatactt ctaaacaata
   123961 agatagtgat acctaccaca aaagacatag attatggttt agtattagga aatttataca
   124021 aaggagacct ttatactgag cttccatatg aagatataaa agaagtatct atttctaaga
   124081 ctcatattat tatattactt aatgatggaa caatgtatgg atgtggtaca aactaccatg
   124141 gagaattatt gcaagacttg tctataaatc aagtggatga atttgtgcag attaatgtat
   124201 cagatgtaaa gcatgtttca tgtggagata actttactta ttttataaaa tctgatgata
   124261 gtctttggtc tattggtaaa aattccgaat atcaattagg tataggtcac aataatccag
   124321 ttactgaatt acaaagaatt acaactatat ctagctgtaa agaagtacat tgtggtaaaa
   124381 actatacatt agtagtaact acaggtaatg aattatttgt acaaggatat aatgataagg
   124441 gagctttagg attaggaagc gatagtgaaa atactataat taagttcttt acaaaagcac
   124501 taacagacat aagagaaata aaatcttatg gaagtgacca tatattagta cttaaaaatg
   124561 ataattcagt atgggttact ggaaaaaata gggatgtata taaaattgaa caaccagtag
   124621 aatttttaaa agaatttact atagtaccta tttctgaaga tgtaaataca gtaaaggatg
   124681 tacttgcaac agacaataca ttatatatta tatcagaagt aggaacgaca aatgctgcta
   124741 tagaaattac tgaaaaatca atttcatcaa ttaagataaa aatacaagac cctaataaag
   124801 atataagtag aatagaaatg cttataaatg gtgaaagtgt aaaatctgta agtgatttaa
   124861 ctactgaaaa aatatccttt gaagtaccac cagataaaat taaaatagga gagaataaga
   124921 tactatttag agcttattgt aaaggtgatg atttatatgc atctttattt atttttaaag
   124981 agagtactgg aaattctata attaaagatt cttatgttat gataggtaat agaatgtaca
   125041 aggtagttaa tacaacatct aatgaacaag atattacaat tacactagat agaggacttg
   125101 aagaagattt aaatcttgga gaccctatat atcaattaat aaataaaact aaagttcaag
   125161 taaaaataaa taaatctgac ttattcaaag acatgaaact agttgaaatc aaaaaatcag
   125221 actcaagtta tcaagaaatc tatgaattag aagaagccaa cataaaaagt gctcagccta
   125281 aaatcatagt agaaaaagga gataaatgga cagctataaa acgtccatct atgattttta
   125341 gatatgatgc tgaaaacaac gagccacaag cttaaaatgg aggtgtaaaa attgtttaaa
   125401 ttcgataaaa ataaaataga acaaatcaaa caaggtagaa aagtagaaat gcagtataaa
   125461 gacatttcag acataagtat aggtcaagca aagcaagatg atgatataac aaataatttt
   125521 atagcaaatg cagaaatata tgagatgttg ttaagtcaaa gttctgtcaa tgaagcaagt
   125581 aatataagca cttttagtgt aagaaaatct ggaggtgaga gtggaatggt agaagtatat
   125641 gtagctttaa ttttaagagg cagaaaaaca atagaagaag taccagcagt aattagagag
   125701 caagttagaa ttagatgtaa agaattagaa ataccagttg aatagtaaat ttagaataac
   125761 tatgtattag ttattttttt tatgtaaagt acaaggtctt aactttaata agtaagcctt
   125821 gtacttattt tttgttatat tagaaattgt atatatattt attatttatt caatctataa
   125881 attaaaccta caatttaaag tacagaagat taaattgata atcctgaaaa tataatattg
   125941 catgatgtaa gaatataaca aaaattaaag ctataagtat aaaaaattta gacaatagga
   126001 ggctataatg gataaattaa taaccgaatt gagtagtctg ggggcaatag gtatactatg
   126061 tgctctatta tttaaaaata ctatgcagga gaaaaaagaa gatagagaca tgtataaaaa
   126121 aactgtagaa aattttatag aattatctac acaacaacaa gaaataaaca aaaatatact
   126181 tgttcaaatg ggaataatga aaacagatgt agaggaaatt aaggaagatg ttactgatat
   126241 aaaaggtatg ttacaaaacg gtgtataaca tgaaagtagc agtagcacca gattatatat
   126301 tattaggaaa agataaagta gtattgtaga tagtgcccta ttttattgag aaggatttta
   126361 tattttaaaa tattaattaa aaaaagtaat aaaaataata tataaaaata acatataaaa
   126421 attcaaaaag gagttaagct taaatttgat tagaaaaaat caattttaag acaactcctt
   126481 ttttttatta aattattgtc tattaaccaa aatagctatt ttagcatctg gattataact
   126541 tatctgaacc atttgatttt tcttaacatg ttcaaggtct tcaccaccat aagctatttg
   126601 taacttaact ggtaacttac cttgttttat aatagcaacg tactcttttt tacctttttt
   126661 ctctaaacta atcaaattgc caacataagg tttaaagttc tgatactttt tactagaatt
   126721 tcttatgtag aagaaagcac caacagcaat aactaaattt atgccaagtg taacccaaga
   126781 attgatttta agcatagctc cagcgattat tatcacgaac attaaaacga taggtaatat
   126841 agctttctta agaagcaatt tacccattat ttcattagcc tttttctcag ggccactcat
   126901 agtttttgat ctagcaaatg attgcgcgaa tttgtctctt aagcccattt tatcctccta
   126961 attttaataa atatttagtt ataataacga gatattactt gaaactaaaa atttactaca
   127021 tttatattat gtttgacttt tgtataaata attacattca agtaaagcaa aatatactaa
   127081 ttattttatc ataaaattat aaaaaagaaa ataaatgaaa taaaaatatt agaacaaaga
   127141 aatgatgtaa aatcgtatca aaagcaacat aaaaattatt tatctatttt ctcatcttta
   127201 tttttgttat actcaatttt tcctaaatcc ttctcttttt catattcatg aagttttaat
   127261 tcaatcatac cttctatttt ggctttatca taatcattta actttctaaa gttgtttaaa
   127321 agctttattt cattagagtt tatgctatta agtggatagt ttgaggagga atcgcaaatt
   127381 aaatctgatt tatgtgatag attatctcca tttaatagcc agtctactga aacattaaat
   127441 atctcagcta tagattttaa tatttcataa tttggttttc taatgtttct ctcaaattta
   127501 cttaagttgt cacagcctaa catttcttct agttcatatt gtttaaggtt ttttgctttt
   127561 ctcaaataaa caattctttc tcctaaagta tccataaaca ctctccattc aattaatgtc
   127621 aaaaagactt tttaagatgt aaatagtttc aaattaaagg tcaaaatgac ataaaaacca
   127681 ttgacttaag gtcaaaatga ctttataatt aacttaatga tacgaattta catcctaatt
   127741 ttagcacaaa gtaatcaaaa aatcttattt agtattaaat aaatttatat acttaatatg
   127801 tgtacatatt aaaaatatat actaaataga gggggtgcgt aagctaaagt aatataaaag
   127861 taaatataaa tcacttagaa aggaagttga taaatggatg ctcgaaaaaa atggatacct
   127921 tttttgggag tgcaagtcaa gcaaagactt attgaattaa atatgactca aagggaatta
   127981 gcgaagaaaa taggtgttaa tgaaaactat ttgtcagcta ttttaaatgg aagaagaaca
   128041 ggtaaaaaat ataaatcatc aatttatcaa ttacttaata tagaatattc agaagatgat
   128101 taataaatag tatataaagt aggtgaatat tcttgtgtgc aaattggatt cagatggggt
   128161 tatagagtgt tgtagagcaa ttgatgattt tattacagca cttagtaata taaaaagctt
   128221 aaatatggaa agattaaata ctttaactaa atattctagt acatgttcaa tccttcttaa
   128281 agaggggaat tatgaaggat gtacaattgt gtatagaaag atgttggaag aattaaaaac
   128341 atgagtaatg catttcttag gaatataaat tatacataga aatgtattat atttttcaaa
   128401 gtacttaaac taaaatatgg ataagataat ctaaatatta taaatgtgct tgaaattaga
   128461 ctatacttgt ttttaaataa tccaatatcc atattttagt aatatactac aaaaaaagaa
   128521 ggttaataga tgatgtaaaa tcgtatcaaa ttatgtatgt ttaaaccatt ttatcttcat
   128581 tattattaga ggaatgcttt tttaagtctt tatattcaga tatcttaagt tcaagtattc
   128641 cttctatttt tattttatca cgttcgttta gttgtctgta tagatttaat atcatcattt
   128701 catcattagt aacatgtaag taatcttctt tatcttcttt tacactacta ttgacattta
   128761 ccttctcttt accatagaga agccagtcag tcgtaacatt aaaataatca gctattgaca
   128821 ttagtatatc acaattaggt tttctatctc ctgtttcata cttgcctaag ttttcaaatt
   128881 ttaaaatatc cataagtttg cgctgagtaa gttttttgga gtttctcaaa taagcaattc
   128941 tttttcctaa agtatccaca aaatacactc ctttcttttt atgagtaatg tctaaatgac
   129001 atttgaaatt aaaaatatat aaatttataa tataaaacta ctaaattaaa gtctaaatga
   129061 cattttgctt aaattaatat gctcataata tgattttaac atattatagt tgaaaatata
   129121 tggtttattt tgatttgtat atataacaat agatttaatt gttataaaaa tgtaaagggg
   129181 tgtatgaata gattgtataa atttatttcg ataaactaag attgcttttt gattgtctgt
   129241 aaaagagaaa aagattaaga taaaaatagt attatattgt aatttatatt aatcaattac
   129301 aaagatttta tgaatttatt ctttagggta aaatatttaa gaataagata aatttacaat
   129361 ataatactat aacactcttt tatctagttt tattttcttt atagaacaat aatattataa
   129421 atgctagtag atttacacag aatactgtta tatacatctg tttgaatcct gagtttagag
   129481 tagattgtag tgtattttct atttttgttc tattattttc tatggaattt atataatcca
   129541 attttgattt atcaaaagcc tttggtattt cagtttttac ctcttgtgtc tttgctaaaa
   129601 ctgcttggag tgattttttt tgctgttgca ttgtatcaag gcttttttcc atgtctttct
   129661 tttggtttat agaattattt aacttgcttt gtagctcttt cttttgagat tccattgatc
   129721 ttagtttttt acttaattcg ttcttttgag ttttattttt ttgtaacttt gtatttaagt
   129781 catctcttgt cttttttagt tgctgtattt gagcatttaa actttctttt tgttcattta
   129841 catttggttt attctcgctg gaattgttat tcttattttc tgtagaatca ttcttagtgt
   129901 cgtctgattc agaattactg gtattactct ggttttgttc atttgagtta ttttcgttat
   129961 cagtaggagt cttttctgta gtaggtattt tattataagc agttgtaagt tccttgatgg
   130021 cctcatcttg tttttcaaga ccttgttcca taccttttat acctttgtca acaccagcaa
   130081 tacctttttt tacaccatct attccttgat taataccagc tctagctttt accatattgt
   130141 caataccagt ttgaactcct ttaataccac tatttagttt attttcacca tcttcaatac
   130201 cgtttattcc actttgtgtt ccatctattc ctttttgtac atttttctgt attttagtaa
   130261 ttatagatgg aactttttca tcaaacattg ttgttgatat ttcttttgtt atattggtaa
   130321 tgttggttgt atctgctgac tgaactttat taagtaagga ttttggaagt ttgccacctg
   130381 tcatgtccat atttatattt gaagtatcat tcatatttgg gatagagaca ttttttaaat
   130441 tttttgccat ttcagggtct gattttaagt catctatcat gttttcaagt tcttcaagtt
   130501 gaactatttt aggagttgag ggctttccaa ctaagtccat aatattatct tgcacagata
   130561 atcctgcatg tgctataaat ccaatcatta tagctggaga aattgaagta ccaattgagc
   130621 gtatcaagga taatgttgca agtgctgaat tagattcttc taatcttgta tttgataaca
   130681 tcatatagtt tagaggagtt cccatagtaa agcccattcc taatcccata aatattaaac
   130741 ttacacatac actaaataca gtattggttt ttagagcaat taaaactagg taaagagagc
   130801 ctatcataga tacagaaaat cctagtaata gtattttctt tgccccaaac ttgtcaataa
   130861 gtcttccgct taaaggagca gcaatacctg caaataatcc caatatagct acaaaatatc
   130921 caccagaacc agcatttatc tttaatgcat tttcagcata ctgtggaacg aataccatac
   130981 ccatcattcc aataccaaca attaaagata aaataagtac tatcaatatt ctcggattta
   131041 aaaaatattc aaagcttaaa atagggtctt tagctctatt ttcaataaat atgaaaatag
   131101 gtataagtac aataaatgtc aataagtatg gataaactga tatatcttgt atagaatttt
   131161 taaaattaaa aaagtctata ttcataagac catataatag tgatacgatt atacatatca
   131221 acatcaatgt accaagctta tctatttttt ctttagattc agacttattg tttttaatac
   131281 agaaaactcc accaataagt atgattaaac aaattggaag gtttacaaaa aatagccact
   131341 tccaattttg agttccaaag atacttagaa ttgtgctacc aatgcttgaa cctaaaatat
   131401 tggcaatacc atatgttgcc ccaactaaac ctaaagccat gcctctttta ttttctggga
   131461 aggtagttcc aaattctgct gtagcaattg gcatgattcc accaccacca attgcttgaa
   131521 taacacgacc aattaataaa atatagaaat tggaaaatag tgatgataat ccacatatta
   131581 atgaaccact accaaataga aatatactaa ctagatacac atattttctt cctattttat
   131641 ctgctaattt tccagagata ggaattacag aagcgtatgt taatgtgtat atggtaatca
   131701 tccaaattcc cgttttttca tttactccaa ggctattttg tataatcgtt cttgctggtg
   131761 atactattcc agtatcaata gctcccataa atatacctaa tagataaagt gtaagtacta
   131821 aaaatatttt tggattactg tccttgttct taatactagt attatgattc aaggtaaaca
   131881 ccaccttaat gtattaattt ttcaatatag ggttttaaat cttcaaattc tatatgaaga
   131941 tatgttgaat atgaaaaaaa catttttatt atgatattgc atactaattt gtcattatta
   132001 aaaaaacttt ctttttctaa agcttcatat actttatttg aaagctgttc atgaaagtcg
   132061 tctttgtgtt ttttcatttc aaaaaatctc tctgtttcaa aagtgtttaa aaagtcattg
   132121 tattggatat tatgaacttt gtttataaaa tttcttattt cagtaaaaat aatgtttagt
   132181 ttttttatgt aatcttcagt gtttttattg gagtattcaa ttcgccttat caataaatcc
   132241 cattcagatt ttgtgatata ttctattatt tcttgttttg aattaaagta attatatact
   132301 gtacctgcac ttataccaca cctttgagct attttcctta tgctaatatt cgagtaatct
   132361 tcttctaaaa tcatatcccg agatactttt aatatatctt cttttacatt ttctaaaatc
   132421 tttggcatat taccacctct tttattaaaa ttattatgaa cactgtttat tatactcctt
   132481 taaaatttat taatcaatat gtaagctata atgtataata ttattatata gatatgatag
   132541 aaaataagtg tctttttata aatatctatt atattaaatt tgtacttaag tatgattatt
   132601 tattgaaata tgtgatatta aatttttctt tttaataaat taaatattat atgataagga
   132661 gaatatggtg atggaaaaga agtatgtaat ggcattagac caaggaacaa ccagttcaag
   132721 agctatacta tttaataaaa aaggcgaaat agtgaaaatt gcacaaaaag agttcaatca
   132781 aatttatcca aaagctggat gggtagagca tgaccctatg gaaatatggg ggtcacaaag
   132841 tggtgtaatg agagaagtta tagaaacagc aggtataaga ccagaagaaa ttgcttcaat
   132901 agggataact aatcaaagag agactacggt tgtttggagt aggtatactg gtaaacctat
   132961 ttataacgca atagtatggc agtgtaggag aacatcagaa atatgtgatg aacttaaaaa
   133021 taaaggattg gaagaatcaa taaaagaaaa aacaggtctt ttaatagatg catacttttc
   133081 agcaacaaaa gtaaaatgga tattagataa tgtagaagga gctagggaaa aagcagaaca
   133141 aggagagtta ttatttggaa ctatagatac atggttaata tggaatttaa ctcgtgggaa
   133201 agtacatgta acagattact caaatgcatc tagaacaatg atgtacaata taaatgattt
   133261 agaatgggat gaggatatat tacgagaatt ggacatacca ataagcatgt tgccattagt
   133321 aaaaccttct agctatgttt atggtcatac agatgagcgc atgttatcag gagctaaaat
   133381 acctattgca ggatgtgctg gagaccaaca agcagcatta tttggtcaaa attgtgttga
   133441 agaaggtact gcaaaaaata cttatggaac gggttgtttc ttacttatga atacaggcag
   133501 taacatagtt aaatctaagc atgggttact tacaacaatt gcttggggag ttgatggaaa
   133561 agtaacatat gcattagaag gaagtatatt tattggagga gcatctgttc aatggcttag
   133621 agatgaatta aagataattg aatctgcaaa agatagtgaa atgtatgcaa atagggtaga
   133681 ggatactaat ggtgtatatg tagtgccagc atttacaggt cttggagctc catattggga
   133741 tatgtatgct aggggttcaa ttttaggact tacaagagga gcaaaaaaag aacatatagt
   133801 aagagccaca ttggaatcaa ttgcttatca gacaaaggat gttttagaag caatgcaaaa
   133861 cgattcaaaa ttaaaactaa aatcattaaa agttgatggt ggagcaagta ataataattt
   133921 tttaatgcaa tttcaatcag atatattaaa tgtagatata gatagaccca aaatagtaga
   133981 aactacagct ttaggagctg cttatttagc agggttgtct gttggattct atattggaag
   134041 aaatgaaatt acttcaaagt ggtcagtaga aaaagagttt aatccaaata tgagtgaaga
   134101 gaagagatgt aaattatata aaggatggaa aaaagctgta tcgagagctt taagctggga
   134161 aaaagaagat gaattggata tttaaaaatt aatcaaagtt aaatttattt gaatttaaaa
   134221 agagctttat gtaaaatatg aagctctttt tttgttgtta attttgcatt tttatataat
   134281 catactaaat tatataattt atttttcgtt ttcatataaa aacattggta tagaattgta
   134341 aatgtgttgg tcaccaacta ctaagagaat gtctccttct aaaaattcaa tatatggtcc
   134401 aggagatatt ataagttctt cacctctttt aattgcaact attgtagcac ctgtattttg
   134461 ccaaaattta gtttgtgcag ctgtttgacc aatatatttg caattagaat ttatggtgaa
   134521 ctgaacgggc actaaaggat tgattatttc aagtctgttg gaatagtcta aaattttatt
   134581 tatagtatct aatatttcat tttctaaatt agatttagta tctattaaat tataaagtgt
   134641 tgatttatat gatgatatat ttgtaatatc tctatatttt tttataaaag aagaagcttt
   134701 gtctggagat agtacaataa cacctttacc ctttatgctt ttaacaacgc caatgtcctc
   134761 taaaattttg acagctcttc ttatcgtttc tggagataca ttgtatttac cagccaaaac
   134821 agagcgtcca aatagtactg aatcctcttg tatttcaccc gtgtatattt tatttgcaat
   134881 atccaacgct attttttggt atattggcat cgtatagttt ttatccattg tttttccccc
   134941 aatacaaaat ttatgttaaa aaaatatata atcttaacaa tactattgta taatttatag
   135001 gtttatatgt ctacaatatg tacaaatatt gtgcatgttt taaaataata ttttaacatg
   135061 catttagtat acatgatttt attatactta aaactatata aagaattaat tataaaaata
   135121 taaagatatt ttacttacaa agaatgataa ttatatagat gaaagaaaca aataaatgaa
   135181 gaaaaatgat tctgtcttgc atataaagtg attaaaaatg aaaaatactt taaaaatgaa
   135241 ggttaaggcc cttattttaa gtgaaaataa ttaattatta actaaaaaat ggtaaaaaga
   135301 ttttttgaaa aagaaataca aatgaatgtt caattaaaat aattgcaaaa atattcctta
   135361 aatggtaaaa ttatattaat taaatgcaat agaatagttg caaaaataaa attgaataca
   135421 agtgataaaa tatttcatgc aatatataaa ataaacaaaa tttaaaaatt aaaactactt
   135481 attctatcaa aatgttagca aggagggggt cataaattgt ataaagtaga tttaaatagt
   135541 gatttaggag aaagttttgg aacgtataag attggtttag atgaagaagt tttaaaatat
   135601 atttcatcag ctaatatagc ttgtgggttt catgcaggtg accctagtca tatggaaaaa
   135661 acagtacagc tagctaaaaa aaatggagtg aaaataggcg cacatccagg tttcctagat
   135721 ttaataggat ttggaagacg tgagatgaaa ataacaaagc aggaagctaa agattataca
   135781 aaatatcaat tgggtgcttt aatggcattt gcaagttcaa atggatgtaa tatacaacat
   135841 gtaaaaccac atggagcatt atacaatatg gcagctaaag ataaagagtt agctatgggg
   135901 atttgtgaag ctatatatga agtcgataaa gatattatac tgttggggct atataatagt
   135961 gaaatgataa attctgctaa agaaattgga cttaggtttg caaatgaagt atttgcagat
   136021 agagcttatg ataataatgg ttttttggtt ccaagaagtg tagaaggagc agttatacat
   136081 gatacaaaac atgcaataga tagggttgtt aggatggtaa aagaaggaac tgtagaaact
   136141 ttaacaggtg aagttataca tatcaaagca gattctatat gtgtacatgg ggacaatcca
   136201 aaagcaatag agtttgtcaa agaaataaga aagcgttttg aattagaagg tatagaagtt
   136261 tgtccattag aaaacataga agtttgttcg tcagagaaca tagtataaga ctgataacat
   136321 gagggggaga taaaatatga gtacaaaaaa tattacagat aaaactaaaa ataaaaaaga
   136381 tgtcggagca cttatagggg ctgcatttat aatggcaaca tcagcaattg gaccagggtt
   136441 tttaactcag actgcacaat ttacccaaga ttttggacca aatttttcat ttgtaatttt
   136501 aattacaaca atccttttta taggggctca agtaaatgta tggagagtaa ttggtgtatc
   136561 aggacttaga ggtcaggata tagcaaataa aataataccg ggattaggtt atttagtagc
   136621 ttttttagta gctcttggag gattagcttt taatatagga aatgttggtg gagctgcact
   136681 tggtatgaat gtaatgttta atatgaatat gacattagga actgtattaa gtggattaat
   136741 agctatattt gtatttatgt caaaaaattc aaattctcta gtcgataaga taactaaatt
   136801 tttagcatta ggaatgataa ttatagttgg atatgtagca atatcaaatc atcctcctgt
   136861 tggagaggca gtatcaagaa tggtaaaacc agaaaatcca aaaggattga tattcccaat
   136921 aataactcta cttggaggaa gtgttggagg ttatataact tttgctggag gacatagatt
   136981 aatagacggt ggaataacag gagaagaaaa tataaaagaa ataactaaat cttctctttt
   137041 gggtatatta gttgacacaa tgatgagagt tcttttattt ttagcaatac tggcagtggt
   137101 ttcaaaaggt cttcaacttg acccagaaaa tccagctgct tcagctttta aatttagtgc
   137161 aggagcaata ggatataaat tctttggact tgtattatgg tctgctgcaa ttacatcagt
   137221 tataggagct gcttatacat cagtttcttt cttaaagaca ctaaatcctt ttatagataa
   137281 atatgaaaaa tattttataa tagcatttat agcaatatca acacttataa tggcatttat
   137341 aggaaaacca gctactttat taattttagc aggagcttta aatggattga tacttccaat
   137401 cacattagga attatgctta tagcatctaa aagaaaagat attgttggag attacaagca
   137461 tcctacatgg cttttaatat ttggattaat agtagtttta atatctgcat atacaggaat
   137521 aacttctctt agcagcctag gtgctttatt tgcttaattt agaagaggtg acatttatgg
   137581 aaactagata cttgatatca ggggataagg cagtggttgc tgaatttgga aatgagatat
   137641 cagaagatat aaacaaaaaa gtaatttcat ttatgagagc aatagaaata tcgaatctta
   137701 aaggtattgt aacagaaatg gtaccaacat ataggtcact tatgataagt tataatccat
   137761 tagaaataga ttttgatagt ttgattgaga atttaaaaaa aatagaagat aatttggaaa
   137821 gtatagtatt accaaaacct aaaatacatg agattccagt atgttatgat gaggtttttg
   137881 gtatagatat taaaaacgtt gcaagctaca ataatctcac tgtagatgaa gttataaaaa
   137941 tacacacaag cagagagtac ttgatatata tgctagggtt tactcctgga tttccatatc
   138001 taggtggtat ggatgaaaga atagctacac ctagattaga agtgccaagg actaaaattt
   138061 atggtgggag tgttggaata gcaggttccc agactggtgt atatcctatt gatagtcctg
   138121 gtggatggca aataattggt aggacacctt taaaattata tgatgaaaat agagaagaac
   138181 agattttgct tagagctgga gactttataa aatttgttcc aataacatta gatgaattta
   138241 tagaaatcga aaaaaataac ttaagtattt aaatatcgtt atagtacagg gagtggtata
   138301 tatgggattc aaagttgaat taggaggttt ccaaacatta atacaagaca gaggtagagt
   138361 tggctatggt caatatggtg tatctggatg tggagcaatg gatgagtatg cacatagagt
   138421 aggaaatata ttagtaggaa attctgaaga tgaggcttct ttagaagttt taatgttagg
   138481 tcctacaatt acctttgatg aatatacgca aatagcagta actgggggag atttaggggc
   138541 taaaataaat ggaaaagaaa ttcaaaactg gaggtcatat caaataaatc caggtgatgt
   138601 attatcattt agaggtgtga aatcaggtgc tagagcctat gtgtcaatag ctggtggaat
   138661 agatgttcca cttgcaatgg gaagtaagtc aacttataca agatctaaaa ttggcggatt
   138721 tgaaggtaga gcacttaaaa aaggagatta tataaatact tttattcagg aaaaagattt
   138781 tacaataaat aaaaaattaa attcaaaata tattccaact tatagttcag aaatcgtact
   138841 aagaattgta aaaggtcctc aatttgatgc tttttctaac ggtgaagtag agaaattttt
   138901 atcaaataaa tacaaagtta cgaatgaaat agatagaatg ggttgtagac tagatggaga
   138961 gagtataaag caccttaatg gagcagatat tatatctgat ggtatttctt atggagctat
   139021 acaagtacct ggtcatggaa aaccgattat aatgttatca gatagacaga ctagtggtgg
   139081 ctatactaag atagggaacg ttataagtgt agatttgtat aagttagcac aagcaaagcc
   139141 aaatgatgta gtaaaatttg aacttgtaga tatatatgaa gcacatagac tattgagaga
   139201 gcaagaagat aagattcaag atatctacaa gagtatgaaa aatataagag ttgtaaaggc
   139261 aaaagtatta aatgatatag cagtttaatt taattttaac aaatacaatt tttattataa
   139321 tttataatat aacttacaaa tagctattta ctatttacca taattaagat ggtttagatt
   139381 agtcaaatag ctattttttt agtttgagta aatattttaa atttaaataa atacttcaat
   139441 tttaaaataa aagcaatatt taaatttatt atattatcta caaaaagtag gtgtgttatg
   139501 ttgagtttat ttagatttta ttggccaaat tggaggtgat ataactccat atccacgagc
   139561 tattgtatct ttacttggat tgatgatttt atgtggtaca ttagctttta taaatgttga
   139621 gtcacctgga tttaatctaa ctaccttttc acccatacaa atatcaacca caccactcgt
   139681 taccaccata atttcttctg atgcatgata gatataatct ttagcatcct cactttctgg
   139741 tttaagttca aactctacaa ataaaattga aggtgtaaat tcagttgtag gcattggaga
   139801 tactatctcg taaaacattt cactctttgg aaatttcatc ataactctat cttcttttct
   139861 aattactaaa tcatcagtat tattgtcatc cataaacata tataaaggag tgtctaaaac
   139921 ttcagcgatt tttctcaatg aagacaagga tggttcaata gcatctcttt ctatttgaga
   139981 gatataactt atagataaat ctgtcaattt ggaaacatca cttaatgttt ttttcttgct
   140041 ttttcttata tttctcatct tttcacctag cataagaacc tccaaataat aaaattaata
   140101 taaaatattc gcttaaaaca aagtaattat agcacaacat agaagtagtg gcaataagaa
   140161 tacatagtag attttgacaa ttaaaattta attaaatcca aataaaagtc tatgaaaatg
   140221 aattattgtt aaattaatat aaagaaaata ataataaaaa aatttaatag aagagtatta
   140281 attgaattaa gattatcaca ttatattttg gaaaagagta aattttcagt aaattatctt
   140341 gacatatata ttgaagtaat aatataattt aaagtataaa attttaaaaa ttgaattata
   140401 acttcaaaaa ataaggaggg taatatgaag ataacagata tcaaatttga aaagcttaga
   140461 attaaattaa aaaaacctgt agtagtttca tttggagtaa ttgaatatgg agaaagtgta
   140521 attttaaaaa ttgaaactga tgaagggtat tgtggatttg gcgaagcagc acctcttgca
   140581 gcagttacag gtgaagtttt ggataatgtt ctttcagtat tgcttatgtt taaaaaagag
   140641 ttaataggca aagacccact agatattgaa accatacata caatcatgga tggaattatt
   140701 ataggtaata cttctgcaaa agcagctatt gacatagctt tatatgatat taaaggaaaa
   140761 attatgaatg cacctcttta taaagttctt ggaggatttg atagtaaagt ccaaacggat
   140821 attactataa gtatagataa gccagaaaaa atggcagtag aagctttaga aagagtaaaa
   140881 gaaggtttta ggatattgaa gcttaaagca ggtataaatc ctgaagacga tattgaagct
   140941 gtaaaattaa ttagagaagc cgttggagag agtataagaa ttagaattga tgcaaatcaa
   141001 ggatggaacg taaatagcag tataaatact atcaaaaaat tagaagaatt taatgttgat
   141061 gcaattgaac aagcacttcc acattgggat ttagatggta ctgcttacat aagaaataaa
   141121 agtaatacaa aaattatgat agatgaatcg ttacattcac caatagatgc aattaaggct
   141181 ataaaaaaga atgcagttga tacatttaat attaagctga tgaaatcaag tggaatatat
   141241 cctgctataa aaatcaacaa catagctgag gcaagtggag taaattgtat gttaggatgt
   141301 atgctggaaa cgagaattgg tataacagca gcagcaaatt taatagcatc taaaaagaac
   141361 ataacagaag ctgaccttga tagttttatg ttttgtgaag aatcaaaaga tatatctgga
   141421 ggatttgtaa tggatggaga tattatgaat cttgtcaata aaccaggttt aggaatagaa
   141481 gtaaacttat gataaatttg gaggttaaat atgaatacac ttttttcaaa tccaggtagt
   141541 atacttgctg taatgacatc aatgattgca ttgggttttt acttacaaag atacaaagcc
   141601 attaaaagct taggaccagc acttacaata atcataatgg gaataatact ttcaaactta
   141661 aaagtagttc cagtaagtac tgagttatat ggaactattt caacatatgc tatcccagtt
   141721 tctatgacta taatgttgat gagtgttgac ttaaaagaaa tgacaaaatt atcaagagaa
   141781 cctttaattg caatttttgt agctgtatta actgtaagta tcatggcatt tttatttgga
   141841 ttagtatttg cagaaaaaat atcagaaggt tggaaggttg ctggaatgtt tgtaggtaca
   141901 tacactggtg gaagtgctaa tcttacagct attggaacag gccttaatgt aagtagacaa
   141961 actcttgctg cagcaaatgc agcagactat gtaattggag taccaacatt gatatttatg
   142021 tttgctctac cagcaatatt aaaaaattca aagaagttta aaaaactttg gccatatcat
   142081 gtagaagaaa cagaattaga agattgtcaa aatgaagaat ttatggagtc aaaagaatgg
   142141 agtattaaag atatagcttg gatgttggct ataggttttg ttgttacaga agtttcaaca
   142201 atacttgctg gatatttcaa ttcaagtttt agtagtgcag caagaatact tttagttaca
   142261 acaatttcaa ttataattgc tcaattaaag ccagtaaaga aactaaaggg aaatttagat
   142321 ttaggattat ttgttgcatt attcttttta tgtacaatag gtttttcagt agatataaaa
   142381 gagtttttag gttcaacttt tactataaca ctttactgtt ttagcataat ttttgcttca
   142441 tttgtttttc atttaggcat aactagactt ttaaagataa agtatcaata tgtaatactt
   142501 tctatagtag gagcaattgc tgatggtcct acttcagctt tagtagctgc ttctgcaaag
   142561 tggaattcgc ttgtaagtgt agcagtcgta atgggagtaa ttggtggagt attaggaaat
   142621 tatgcaggta tatcagtggc atatgcaata aagatgtctc taggattata ggggggagtt
   142681 taattgataa aatttaaatt atacatatct ggactataca gtggaaatgt aatctttgat
   142741 ggcgatttat taattgaaaa gttgaatcct tttacaaata aaatagaaag tttaaaacca
   142801 ataagcaaag aagaaaatac atactattta aatcttacaa aaatagattt aaagtcttta
   142861 tttaataact ttgatgtata tactaaaagc ttagtaaaca cagataaaga cacagttata
   142921 aataacttag gagaaacgca ttctaaactt aatgaatata tatgggttca aagaaacaaa
   142981 aagttcccac tagatataat tattgtagat aataaaatag taggttttat ctgtttatcc
   143041 agagaaactt gtactatatt aattatggat ggatatgaag agtatactgt attaaaagaa
   143101 tgggaaaaaa cccataaaaa tgaagagata tattctataa gatttggtgg aaattatatg
   143161 attgatatga aagatggtat aaaactttct acagatgtat atctccctga ttttgtagat
   143221 tctaccaaaa aagcaccaac aattcttatg agaactccat atggaaaaga aaatgataaa
   143281 gaaatatatt ataaatatgt acaaagagga tatgctgttg taatacaaga tgttagggga
   143341 agaaatgaat cagaaggtaa gtgggaacct atgattcatg agagggaaga tggagatagt
   143401 accataaatt ggatagtatc acaggaatgg tcaagtggaa tagttggaat gcttggagca
   143461 tcatatcttg gttatgtcca atgggcagct gcatcttcag gcaataagca tcttaaagct
   143521 ttagttagta tagtaacatc aggaagccct tttattgata taccaagaaa aggaggagct
   143581 tttgtatctg gtatgcttgc atgggcattt atggtatcaa gaaataaagt tgatagaagt
   143641 aaaatggtaa gagatgattg ggatgatgtt ttaaacatac gaccaataga aaatatacct
   143701 gttgaagctc ttggatatag aattgaattt ctggaagaat ggttaaagag agtagaaaaa
   143761 gatgagtatt gggatttgat ggattggcat ttacaaaaag ataaaataaa tgtacctgca
   143821 ttggttgtat ctgggtggta tgatgataat agtatgggaa ctacagaggc cttagatgtt
   143881 ataaaggact atgaaaaagg aaagagaaag gctattctag gtccatggat gcataattca
   143941 aatactttaa gagatataaa tggtatttct ttaggaaata gttcattaag atatgatttg
   144001 gattataatt atctattatg gtttgataaa tacttaaaag gtatagaaaa taacatagat
   144061 acgactgctc cagtagagta ttactctgta ggttttaata agtggaagac agaagaaaat
   144121 tggccaataa taaataagat agataaaagt atgtatctaa taagtgatgg aaatgctaac
   144181 acatctttag gaaatggtag attagtattt gataatgatt tagaagaaaa gtatgatagt
   144241 tatatatata atccaaaaga cccatcagta caactaattg atatgtcaga gaatgaagtt
   144301 ggagttccaa ataactacaa agatttagaa aaaagaagtg atatgttgtg ttatacatca
   144361 gatgctttta gtgaagaatt tactgtaaca ggtgatataa agttagagtt ttttgcatca
   144421 agttctgcca aagatactga ctgggttata aaaattatgg acgtggattt agatggaaat
   144481 tcaattaaat tagctgatgg tatacttagt gctagattta gaaatagttt ttataagtca
   144541 gagtttatgg aagaaggaga gatttataag tttacgatta taacttcaaa aatatcaaac
   144601 acgtttaaag ttggtcataa aattagacta gatataacgt ctagtgctaa aaactttatt
   144661 ttccaaaata gcaacacgaa agagggatat aatagtattg aatatataga agcaaagaat
   144721 acgatttacc atggaggtaa atatccatct aaattgatat tgccaataga aaataagtaa
   144781 atttatatag attaaatagt gaggaggtgt ctcaaaatga attttttagt tcgtgagaca
   144841 ctttctttta tacgaaatca aatatatttt catcatttca acaatgaaaa agaggcttat
   144901 ctctctgttt tgagatagcc tcctataagc taaattgatt attttgtagc tgcaacaacg
   144961 ctcatttcaa ctaacaaatg ctctctagca agtctagctt caacacaagc tctagcaggt
   145021 tcaaatcctt tttcaaccca agcatcccaa acagagttca tagcttcaaa gtctttcata
   145081 tctcttaaat aaatagtaac agatagcaaa tgttgcttat ctgaaccata tttgtttaat
   145141 aaatcttcta ttttagctaa aacttcagtt gtttgttcaa ttactcctcc ttcagcatga
   145201 gtttgtccac ataaataaac tgtattgtta tgaactacag ctctactcat tcttccagtt
   145261 ccttcatatc tctttatttc catattttaa atacctccat agttaagaaa tctattaaaa
   145321 atctaaataa taaattaaaa aaagtctata ctatataaaa ttatattata tattctgata
   145381 ataatccata aaaacatata actttttagc tataattatt attgttatta attgaaaaga
   145441 cttattagtt acttgacata gtttacactt ttaattatag tataaattgg aatatttaga
   145501 taattattat ttaatgtata agctaagttt ttaattaata tggctttata catttatata
   145561 gaaaagaggt acgtatgagt agcacaatca aatcaaatcg aataaaaggt ataatgttta
   145621 taatagcatc agcgcttggc tttgcaatga tgtctgcatt cgtaaagcta gctggagatt
   145681 taccaagttt tcaaaaagtg ttctttagaa atctggtatc agctataata gctttttggc
   145741 ttatcataaa acataaagga agtctaactg gtaaaaaaga aaatttaaaa gtacttttat
   145801 ataggtcaat atttggaact ctaggagtta tatttaacta ctatgcaatt gacaagttga
   145861 tgctttcaga tgctaatatg ctaaataaaa tgagtccctt ccttgtagta atattttgtg
   145921 caattgctct aaaagaaaaa ataaatgtaa agcagatagg agctattata attgcattta
   145981 taggagcttt attcataata aaaccaacat ttagtgtaga agtaattcca tatcttgggg
   146041 gaattgcagg agctgtattt gcagcaatgg catatacttg tttaagagtt cttggagata
   146101 gagaagatta ctatacaatt gtatttttct tttcagtttt ttcattagtt actgtagggc
   146161 caattgcttt tgcagtatat gaaccaatga cccttatgca acttatatat ctattactag
   146221 gtggagtatt tgcaagtcta ggtcaatttg gaataacttt agcatataaa tatgcacctg
   146281 ctaaggaaat ctctatattt gactatagta atataatctt ttcagcaatt ttaagtatat
   146341 tcttattcaa tgtctatcca gatatgttaa gtgttgttgg atatttaata gtattttcgg
   146401 cagcatttta tatgttttta tacaataaga agttagataa attagacaaa gaaaagaaga
   146461 agtaaactag ataaaagtgt ttttataatt tgtattgaat atttaagtct ttgtattaaa
   146521 attaaagaaa atttaattaa aaatgtttgg tatattaact tataacagca gttaaaattg
   146581 aaaaattata actgctgttt cttttattaa aaatatccaa atgtctgtaa aaatagacta
   146641 taatagagta gtataaataa tataaagggg ataaattaaa gtatggaaaa agtgaaagtt
   146701 gctgtgattg gagcaggtaa tagaggaacg tatgcatatg ctccatatat ttatgaaaat
   146761 tctgatatat gtgaaatagt tgctgtagca gaacctaaaa aaggaagacg agaactattt
   146821 acacaaaaat ataacctaga tagtaaaaat gtatttgaaa ctttagaaga cttttttaaa
   146881 catgacaaga tggcagatgc agtaataata gctacaaatg atgatagaca ttatgatgta
   146941 gcaaaactag ctcttgaaaa aggttatcat gtactattag aaaagccaat gtctaatagt
   147001 ttagatggtt tggtacatat agatgacttg tgtgataagt ataaagataa gatttttatg
   147061 atttgccatg tactgagata ttctccattt tataataaat taaaagaaat tgtagaaagc
   147121 aaaaaattag gagagctagt tagtatacaa tataatgaaa atataggata ttggcatttt
   147181 gcacatagct ttactagagg gaattggaga aatagcaatg aaaccagccc tttaatttta
   147241 gcaaagagtt gtcatgacat ggatattttg ttatatttag taggaagtag atgcaaaaaa
   147301 atatctgcat ttggaagctt aaagcatctt aataaccaaa atgctagtgg agagatggca
   147361 caaaattgtc ttcagtgttt agttgaaaaa aaatgtccat attcagcaaa gagaatttat
   147421 ttagaaaaag atagaagtat aaatagagct gttcacataa atccaactga agagaatcta
   147481 ttaaatatac ttaagacaag tccatatgga agatgtgttt acagatgtga taataatgtt
   147541 gtagacaata tggtaaatat attacagttt gaaaatggag tgacggctac ttttaattta
   147601 tgtgcattta ctaaagaaaa tggaagaact ataaagttaa tgtttagtca tggtgaagtt
   147661 ggtggggatt taaataaaaa tgagataaga attaaaaaat ttggaaaaaa cgaagaaata
   147721 gttatgaatc catcaaatca acagaatatg gtagaggaat atgatagaaa tcttatagct
   147781 gaatttatta aattagtttc aaataaagaa ctagaaaagg gtagagtagc agcaaaagaa
   147841 gctatacaaa gtcatgtaat ggcatttgca gcagaatatt ctagggtcag tgatgaagta
   147901 gtgtatatag aagaattttt tgatagtgct aagcaaatga ctaaggagat agaagaaact
   147961 atattttaat taataaaaat ttattaaata aaataaagat agattaaata atagaaatac
   148021 gaaaatatgt gttctattaa ggaatctatc ttttttatta aggttttttc ttatccctat
   148081 caaaaaaatc catacattct gataaaagat aagaaagtaa agcgaataag atttctgtac
   148141 ttaaaggaat cgttactgaa tccataaagg tatcaattat gttcatagct agaaaagtta
   148201 gtataaaatc aattataaat tcgcaaagtt tatatattga gtatggtaat ttgtttacat
   148261 atctgaatat atctaaaata gtagtgcata gaaaatcaat tggagtggtt atacaaaaat
   148321 atattaaaaa gaaaattaat acagctccaa gagatttata ttcaaatcct aagaatgata
   148381 agaagccaat tcctataacc gtgaaaatac aaaaagttat accaaaaaaa acagcaaaaa
   148441 ataaaaatac agaaataaat tcgcctaaag gaatccttct tttattactt atcttaatca
   148501 actccttaat ttatgatatg aaatttatat aaataataac attcttaaaa attcataata
   148561 gtcctctgtt tcaaatagta ctgtttgaga atctattttt ttcatatttg gataaaaaga
   148621 ggccttaaaa gctttataat gttctctaaa ttttatttct atcttaaatt tatctggcaa
   148681 ttttattaag tgcctagata aatctccaga taaagctttt ttgacacctt tttcaatttt
   148741 ttttagtgca aggtttggat ggattgaaat tgaaccattt ccaattcctt ttgacacagg
   148801 aacagtgact atatttggat ttagtttttt tgcactctca caaagcattt catctccact
   148861 taaaaatgct acaggaacat tataatatgc agcaatataa gcatttatag taaattcaga
   148921 tgctatttca tcatttattt taaaatagtc ataatcaata tccatagtat gagaaagtgg
   148981 attaccatta caagtagctc cagagtgata gccggtgaat atacatgcat caaagctttc
   149041 atcaattcca gccatcataa ctagtgggtc tttggtccat cctctaagta ttttgacgtt
   149101 ttcaggtaaa atatttggat taatatttct accactgtca tgtgcatctt taacaagtat
   149161 ttcatgtaca ccagattgag tagctccatc acatgctgct gttatctctt tactcatttg
   149221 tgttctatag tgttgtgaaa attcacattc aagttttgtt tcatcccaat ttacaatacc
   149281 acaagtacct tctatatcag cacttaaata caatttcata atatataccc ccttatgttt
   149341 attattgatg ataataacag ataacagaaa atacataatc aataaagggc ataaaaatat
   149401 tatgtcttac tattaattat tattaaatct gtaactgaaa aataactaaa ttggtattaa
   149461 aaaatataac actatgtgtc atttatttat atagtttttt atatctgatg tttatataaa
   149521 attgtaacat ataagtggtt acatttacta gtttaacata gttaaaatag ttaggtatta
   149581 tttttaagtt aaattgatta ttataaaatc gtagaataaa agaaaaattt aatttattaa
   149641 aatgcatgaa atgttttttc ctcaacataa tgctaaatta aactcaaaaa gaaataatag
   149701 aaaaatctta tgtagcttag aaagaatgtg aatgatttaa gggaaaaata gaaatttatt
   149761 atataatatt aggctgtatt atgtaataca gcctaatatt atatgtatat gtgacataaa
   149821 atcttggtaa gtgtaaataa aataaatgtg gaaaacaaat taatgaaatc aagaaaaaag
   149881 taatttaaaa ttcaatttca tcttcccaat taaattctcc tgatttttct acactcttag
   149941 gccagtgact acaccattta ggaacggacg gattttcaac cctatcaacg cttggagtat
   150001 atggctttaa gtctataaca ggactattat cattagcatc aatatatggt atttttatta
   150061 taccattttc atggtcgata ttgataattt gtacagcagt caatgctatt ggattgggtc
   150121 ttataggtga ccttgttgca aatattccta taacgtttgg tccactttta taaggttttg
   150181 gggtttctaa aatacttctt agttcaggat tatcaaaccc atcagcccac caaaatacat
   150241 ttaaatgact gaaatcgtcg agttcattta atgcaggtac atactttttg tctaatttaa
   150301 taaagacctc ttcgccttga atacatattt tacctatagg atttattaat atttctttca
   150361 taatattacc tccaactatt taatttatca tttgtaattt tagggtataa catgacatca
   150421 tgtgagggtc aatataaaat aataaataaa aatattaata gttagaatga taatacattt
   150481 tttacatgga gcatgacacc agtaataagg caatcttcgt caatatcaaa agtagaggta
   150541 tgcaaagggg aagtaatgtt tttttcacga tttgcacaac caaggtggta aaaagctcct
   150601 tcacagtgtc ttagaaaata cgaaaagtct tcagccccaa gagtgggcga gtctttaagg
   150661 ataatatttt cttctccaaa caattctaca gcattttgct tgacgtaatc tactagatgg
   150721 tttgaattga taagagctgg ataaccttcc tcaatttcaa cagaaatact tcctccaaat
   150781 gttttacaag taaaatcgca aatttctcta attcgttttt ttgaaaactc tctagtttca
   150841 ggagtcaagg ttctcaaagt accccttata accactttgt cacaaactat attttccttg
   150901 attccacctt caatctttcc tagagaaata accacagaat cagttggatt tgtgtttcga
   150961 ctaacgattg tctgtagagc tgtaataata tgagcagata taacaatagc atcaatacct
   151021 tgatgtggat aagctccatg acattttgaa ccatgtacag ttaattgaag tgtatcggtg
   151081 gaagcattta gagtgttgta ttttaattca attagatttt tgttgatatt gggatttaca
   151141 tggagtccaa atatatattt tacatttggg ttttcaagac atccatcttc tatcataagt
   151201 tgagccccac caatagtttc ctcggcaggt tgaaaaaaga attttacatt tacatttaag
   151261 taattcttta atttaaatag tatattacaa gtacccagta aaatagcagt gtgtgcatca
   151321 tgaccacatg catgcatttt accaatatta atagatttat aagaataatt aagttcttct
   151381 gttataggta aggcatctat atcagctctt atagcaactg tttcaaagtt tggactcacg
   151441 ttaatgtatg cagttatccc tgtatgattc ttatattcaa tataatttat acctatttca
   151501 tttaagtatt taataatttt tttcttagtt tgaaattctt ctaatccaag ttctggagtc
   151561 ttatgtaaat ctcttcttat atttataatc caatcattta tctcatgaca aagagttctt
   151621 atattaagca taaaacacat cctaactata ttaaaaattt atttttcttc attaattata
   151681 ttattttatg taaatcatta ttatgtatca agtacaaata aaatatctta taattatatt
   151741 agagatattt agtatggaga agaatatatc attttataag aagaggtgtt taaatgttag
   151801 gaataattgc gccatctggg ccattaagaa atacaagttt ggaggaaata aagtttaatt
   151861 tagaaagtta tggttacgaa gttaagtttt ctgaaagttg tagtttaaat tataaaggtt
   151921 atttagctgg taatgatgat attagagcaa gggatataga agatatgttt ttagataaag
   151981 atgtagatat aattatgtgc ttaagaggag gttatggaac aacaagaata ttggataaaa
   152041 taaattatga tataataaag caaaatccaa aaccatttat aggtttttct gatataacag
   152101 gtttaaattt agctttttat aaaaattgtg gacttttacc atatcatgga ataatggcag
   152161 caaatgtagg taaatgggat aaatttacct ataaatcatt ggtaaatgct ttagaattta
   152221 aagatgactt atatttagaa aatccaaaag aagaaaagat ttatactgta tgtgaaggta
   152281 aagcagaggg aataataatg ggaggaaatt tatccttaat aattgccaca atgggaacaa
   152341 aatatgaaat agatgcaaaa gataaaattt tgtttattga ggaaattgga gaacctcaat
   152401 ataaactgga tagaatgtta acacaactat attcttcagg aaaacttgag gaatgtaatg
   152461 gtataatttt tggagatttt aaggattgta ttgaagaaaa tgatttgatg gaattactaa
   152521 tagaatttgc aaataaggtc aataaacctt ctatatataa tcttcagtca ggacattgta
   152581 tcccaatgat aactattcct ttgggcagaa tgtgcgaatt agatgctaca gaaaaaatcg
   152641 ttaaattaaa aaaatagtgt gtatataaat ataatagaaa tatggtataa tcttatacaa
   152701 gtaaaaattt agctaggagg atgaaaaatg tctgatgata gaataataga ctttaacgaa
   152761 ctaaagaaca aagttaaaga ttctgatgta gataaatttg agcaatacat atataactta
   152821 tatttttctg ttatggatgg aaagatgtcc atggctgagt tttcaagaaa aatattcgat
   152881 tatatgagag ataacaacat atctcaagaa aaatttatga aaatacaaaa gcaatttatg
   152941 gagagatatg gtatggacac tgaagaagta gaaaaacaac ttagaaactt tggaatcgac
   153001 ccttctacag caggttttat gagtaataat acttccagca aagtatctac agaagattta
   153061 gagtcattta agaagagtgc aggattttat gagaaatatg gagaaaaaat ccaaccaaag
   153121 agttgtataa caacatttat aaaaaatgac ttaaatgata ttaatgtaat aatcgaccaa
   153181 gaaaagataa tgctttgtag tgatagaaaa ataaatctta tggattcaga actaaatgag
   153241 tttttattag aatataagaa tatgtttaat aaaaaaataa aggtagtaat gtgcgaaact
   153301 acgaataagt atgattatta aaaaatgaat ttaaatactg aagtagtatc aattaattgt
   153361 actacttaaa aataaaaatc gcaatttatt attccttata aatttgtata aggaatatct
   153421 aaactgcgat tttttatatt gtgaagatta gtcataatag atagtgtttt aaattgtaat
   153481 cttctcacta aaactgtgtt tttctattag aaattttatt aaaaataaat atctgataat
   153541 tgtattatat gggatgtaaa gtattagagg cttaacgaat ctcttttaat acattaactc
   153601 cattttgaat catactgttg aaaaatacta agtttaaaat ctcagcaggg tgaatgttag
   153661 gaatatcata agtatctact aaattcatag gtacaactat atttttttca atattatgtt
   153721 gattaaaata tgattttaga gttattgcaa attgatatat gcatatatct gtgcaatcgc
   153781 caactataat tatattatct atattatcaa aatccaaatt ttctaatgca aaaaatccat
   153841 tagtagaatt tttaggaaga atttgtaggt tttctatcga cttaagttca tcaaccaatt
   153901 cactttctac atcattttcc aaacagtgaa caggataact caaaagttct attgatttag
   153961 gagtatgaga atcagtaaat gctattactc tatttaattt gtttgatatt ttttttgtaa
   154021 acatttcaat tggttttatt aaagactcta ctctaggaga gtataatgca ccttgtcttg
   154081 caaagccatt attaacatca attataaata aagcagtttt actcaaatca taattttcta
   154141 ttttttctat tggtagatta tctaaattac tctttaaagc ttcaagttca tttaataagt
   154201 tatccatagt tatacctcca agataaattt aataaaattg tacatattaa ttatataaaa
   154261 gtcaaggagt acaaactatt gtataattag ctgtattgtt ttgagtgtaa aagatttgaa
   154321 gcaatatctg gatagttagt aaaaatacca tctacattga gttttagaca gtgtagtata
   154381 tcatcctctt catttacagt atatacattg acaccaagta gatttttgtg acaaagttca
   154441 attagagatt catttactaa aactagaggt ggatgaaggt aactattacc cagaaattta
   154501 gcaaaattga ctacattgtt tataggtaaa taacacaata atcctgtttt tacactaggg
   154561 tctaatttat gaaagttttt taagctattg ctgttgaaac tagatataag aactctattt
   154621 ttcatattat actttaaaat aagctctaaa acgtcttttt ctatattggg atagtttatt
   154681 ttgtcagttt ttagttctat atttaaaata aggtctgtag gtgaaattag aattaatact
   154741 tcttctaaag ttggaatttt acattcttta ttgttttgat atccttcaaa agatgagttt
   154801 agagttttta attttcttaa agtaaagtct tttacaaaac catgtccatt aaaagttcta
   154861 tcaacctttt catcatgaat aactacaatt tttccatcct tagttctgtg gacatcaagt
   154921 tctattccat atatatccat atacaaacat tttttaaaag ctagaatagt attttctgga
   154981 tactttccac taaaccccct atgagcataa atattcattt atatggttcc ctcctataag
   155041 tataacttat cttataaaaa tttaattaat ataatatatc atattccaaa aggtattgtt
   155101 atatattagt taaataacta tttgtaattt atatattata taaatgtaga aaaataaaat
   155161 catatatgtg ttataatata ttttaaacat tgtaaatatt acgaatttag tagtcataat
   155221 aagtgtaatt ttatgcaagc tcatgttttt agagcttgca tatgtattat taatatattt
   155281 atatattgtg aaaataaaat tccaaaagaa ttttttctat agacttagta gtaaggggga
   155341 attttgatat gtatgaagtt aatttagaac gagctatgaa ttattggatg gatttgttag
   155401 atgattatac gaatatagca aaaattccaa atgatttttt ttataaagat tgttctgatg
   155461 aagtagtaga tgaggttttt aagatgaata ttgagaaaca tgaaaggtta attcaatatt
   155521 ctaaagtgaa caatattagc atagactcta tcatagaaac tatatatggc cttatacttc
   155581 aaaagtatat atatgaagat gatgtagttt ttggtaaaac aatgaatata attccaataa
   155641 gagtaagagt tagacaaagt gaaaaattta tagatgttgt aaggaagcta aaaaggcagt
   155701 ggagcaggtc tttagagtat ggatactatt tgttatcaga tatagagaat aaaaatcatc
   155761 taaatactaa gcttataaac acaatattta tagctaaaag ttttgattta tcatatgatt
   155821 atgacataga aaaaaaagga tatgatttat ctgtaatagt atatactaag agggcactta
   155881 aaataaaaat aaagtataaa ccatctatat ataaaagaga aactattaga agaattttaa
   155941 atcaatttga ttatataata gagcaaataa tagaagataa tgatatttta atagaagatt
   156001 tagaatttgt atgtaaggaa gaagaaaaag tattattgga agactttaat aataatcaat
   156061 atgaagtacc ctatgataaa agttatgttg atttatttag ggagcaagtt aaggtaacac
   156121 ctagtaatat agctgctagg gatgaaaata gaaagttaac atataaagaa ttggatgagg
   156181 taactgataa acttgcaggt tatttaaatc atataggagt ggaaagtgaa gacatagtag
   156241 ctgtaatgtt accaagagat attaacataa ttattacagc aatagggatt atgaaatcag
   156301 ggggagcatt ttttccaata gacacgagta atccagaaga aagattgaat taccttcttg
   156361 aagatagtaa tgcaaaagta gtgataacta cagatgaact caaaagtaag gttgtaaatg
   156421 agaataccat agtactcgat ataaatgatg aagaaatgtt taagcttgga tatgaattaa
   156481 ctgaaaaaat aacatcatca aattgtgcat atacgatatc tacttcaggg tcaactggta
   156541 ggccaaagac catagctata gaacataaga gtttagtaaa tatgtgttat tatagcgtaa
   156601 aatctataag cgctacagaa aatgatatat gtggtatata cttaagtttc agttttgatg
   156661 ctgtaatgaa acaactattc ccttatttgc ttgtaggtgc atcaatagat attatgcctg
   156721 aagaagctaa atttgatgaa tatacagtaa atgaatactg tgaggaaaat gacataacta
   156781 tactagcatt gccaacagca tttgcaaggt tatttataca aaattgcaat aataattcac
   156841 ttagagttgt acagactgga ggagaaagat taaaaggata tagaaagcgt aattatgaac
   156901 tatataatga gtatggacca accgaattta ctgttgtatc gacttctttt catgtggaca
   156961 gagaatatgg aaaaatacca ataggaaaac ctatatttaa tacttatgca tatgtattag
   157021 ataaaaagaa caaactatgt ccaattggag caccaggaga gctatgtcta tcaggcattc
   157081 aaatatcaag aggatattta aataaaaaag ggctaacaga gcaagtattt gtagagaatc
   157141 cttacaaaac ttgtgaatat aataagttaa tgtatagaac tggtgattta gtaagatggt
   157201 tagatgatgg aaatttagat tatattggaa ggatggacaa tcaagtaaaa attgatgagt
   157261 ttaggataga gctatatgag attgaaaata taataaataa tattacagaa attaaaagtg
   157321 ttgtttgtat atcgagaaca aatgatgacg gggatatgta tatatgtgca tattatgtaa
   157381 ttgatgagga agatagtggt aagataaatg aaagaaccat tagagaatat ttaaatgagc
   157441 atctacctcc atatatgatt ccaacaataa taatgaggat agataaaata ccagttacac
   157501 caataggaaa agtaaataaa aaagcactac cagagtgatt ttttattatg acaggtgttg
   157561 taaagtgatt ccatacattt ctttatgaca cctatttttc tgaggaaatc aattgatgta
   157621 aaaaaaagaa ttttctgtat atatttacta tggtgaaaat ttatttataa gaatgattat
   157681 tgtatttttt atacttttcc gtgttttaaa gcattttttt tacaaaatta attttacatt
   157741 aaaaattttt tttattttat atcttaatag tttttagtag aattgaaaaa taaaaagaaa
   157801 attagcataa aaat
//
LOCUS       DAEQJM010000002       105927 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.002, whole genome shotgun sequence.
ACCESSION   DAEQJM010000002 DAEQJM010000000
VERSION     DAEQJM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 105927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105927
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.002"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            203..862
                     /gene="cprR"
                     /locus_tag="KRQ43_000147"
     CDS             203..862
                     /gene="cprR"
                     /locus_tag="KRQ43_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HBH2740529.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            1073..2131
                     /locus_tag="KRQ43_000148"
     CDS             1073..2131
                     /locus_tag="KRQ43_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH2740530.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            2382..4526
                     /gene="fdhF"
                     /locus_tag="KRQ43_000149"
     CDS             2382..4526
                     /gene="fdhF"
                     /locus_tag="KRQ43_000149"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2796..2798,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HBH2740531.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKTWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            4575..5408
                     /gene="fdhD"
                     /locus_tag="KRQ43_000150"
     CDS             4575..5408
                     /gene="fdhD"
                     /locus_tag="KRQ43_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBH2740532.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCASVKSNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            5419..5592
                     /locus_tag="KRQ43_000151"
     CDS             5419..5592
                     /locus_tag="KRQ43_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740533.1"
                     /translation="MCTKKEEQKCSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            5650..6201
                     /locus_tag="KRQ43_000152"
     CDS             5650..6201
                     /locus_tag="KRQ43_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH2740534.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            6226..7602
                     /locus_tag="KRQ43_000153"
     CDS             6226..7602
                     /locus_tag="KRQ43_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH2740535.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            7602..8117
                     /locus_tag="KRQ43_000154"
     CDS             7602..8117
                     /locus_tag="KRQ43_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH2740536.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(8195..9478)
                     /locus_tag="KRQ43_000155"
     CDS             complement(8195..9478)
                     /locus_tag="KRQ43_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HBH2740537.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSHSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            9666..10088
                     /locus_tag="KRQ43_000156"
     CDS             9666..10088
                     /locus_tag="KRQ43_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HBH2740538.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSEKNGENIIRDILDGNISSECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            10190..11128
                     /locus_tag="KRQ43_000157"
     CDS             10190..11128
                     /locus_tag="KRQ43_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBH2740539.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            11314..13338
                     /gene="ligA"
                     /locus_tag="KRQ43_000158"
     CDS             11314..13338
                     /gene="ligA"
                     /locus_tag="KRQ43_000158"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBH2740540.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            13498..14847
                     /gene="rph"
                     /locus_tag="KRQ43_000159"
     CDS             13498..14847
                     /gene="rph"
                     /locus_tag="KRQ43_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBH2740541.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEIADEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARAIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            14847..15317
                     /locus_tag="KRQ43_000160"
     CDS             14847..15317
                     /locus_tag="KRQ43_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH2740542.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            15511..16797
                     /locus_tag="KRQ43_000161"
     CDS             15511..16797
                     /locus_tag="KRQ43_000161"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBH2740543.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            16946..17530
                     /gene="clpP"
                     /locus_tag="KRQ43_000162"
     CDS             16946..17530
                     /gene="clpP"
                     /locus_tag="KRQ43_000162"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH2740544.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            17549..18799
                     /gene="clpX"
                     /locus_tag="KRQ43_000163"
     CDS             17549..18799
                     /gene="clpX"
                     /locus_tag="KRQ43_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBH2740545.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(18870..19397)
                     /locus_tag="KRQ43_000164"
     CDS             complement(18870..19397)
                     /locus_tag="KRQ43_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH2740546.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(19385..19897)
                     /locus_tag="KRQ43_000165"
     CDS             complement(19385..19897)
                     /locus_tag="KRQ43_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH2740547.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            20077..22440
                     /gene="lon"
                     /locus_tag="KRQ43_000166"
     CDS             20077..22440
                     /gene="lon"
                     /locus_tag="KRQ43_000166"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBH2740548.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFNSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     ARKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTAVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            22430..23041
                     /locus_tag="KRQ43_000167"
     CDS             22430..23041
                     /locus_tag="KRQ43_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBH2740549.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23306..24676)
                     /locus_tag="KRQ43_000168"
     CDS             complement(23306..24676)
                     /locus_tag="KRQ43_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2740550.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYALGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDISGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(24851..24966)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25254..26333
                     /locus_tag="KRQ43_000169"
     CDS             25254..26333
                     /locus_tag="KRQ43_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2740551.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKATEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            26725..27405
                     /locus_tag="KRQ43_000170"
     CDS             26725..27405
                     /locus_tag="KRQ43_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH2740552.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            27398..28777
                     /locus_tag="KRQ43_000171"
     CDS             27398..28777
                     /locus_tag="KRQ43_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH2740553.1"
                     /translation="MINIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGVLLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            28948..30033
                     /locus_tag="KRQ43_000172"
     CDS             28948..30033
                     /locus_tag="KRQ43_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH2740554.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            30087..30446
                     /locus_tag="KRQ43_000173"
     CDS             30087..30446
                     /locus_tag="KRQ43_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBH2740555.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            30499..31371
                     /locus_tag="KRQ43_000174"
     CDS             30499..31371
                     /locus_tag="KRQ43_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBH2740556.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            31372..31815
                     /locus_tag="KRQ43_000175"
     CDS             31372..31815
                     /locus_tag="KRQ43_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740557.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYINQNKLVDKSKHTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            31830..32414
                     /locus_tag="KRQ43_000176"
     CDS             31830..32414
                     /locus_tag="KRQ43_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740558.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            32667..33704
                     /locus_tag="KRQ43_000177"
     CDS             32667..33704
                     /locus_tag="KRQ43_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH2740559.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            33785..34150
                     /locus_tag="KRQ43_000178"
     CDS             33785..34150
                     /locus_tag="KRQ43_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740560.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINVAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            34155..34472
                     /locus_tag="KRQ43_000179"
     CDS             34155..34472
                     /locus_tag="KRQ43_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740561.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            34520..36124
                     /locus_tag="KRQ43_000180"
     CDS             34520..36124
                     /locus_tag="KRQ43_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740562.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVVLKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYINVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            36248..37876
                     /locus_tag="KRQ43_000181"
     CDS             36248..37876
                     /locus_tag="KRQ43_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH2740563.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIAKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            38141..39490
                     /locus_tag="KRQ43_000182"
     CDS             38141..39490
                     /locus_tag="KRQ43_000182"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBH2740564.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            39646..40725
                     /locus_tag="KRQ43_000183"
     CDS             39646..40725
                     /locus_tag="KRQ43_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH2740565.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            41070..41978
                     /locus_tag="KRQ43_000184"
     CDS             41070..41978
                     /locus_tag="KRQ43_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH2740566.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGVNIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            41983..44352
                     /locus_tag="KRQ43_000185"
     CDS             41983..44352
                     /locus_tag="KRQ43_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBH2740567.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRLTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPKDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            44677..45480
                     /gene="proC"
                     /locus_tag="KRQ43_000186"
     CDS             44677..45480
                     /gene="proC"
                     /locus_tag="KRQ43_000186"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH2740568.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGINTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            46078..48834
                     /locus_tag="KRQ43_000187"
     CDS             46078..48834
                     /locus_tag="KRQ43_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2740569.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSKFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNTILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEIFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALESKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINGPMLFIDQISTISALEVGNLLMQGKNIEQIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLPNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            48966..49445
                     /locus_tag="KRQ43_000188"
     CDS             48966..49445
                     /locus_tag="KRQ43_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2740570.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTRDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKEIGDLGIDIELRMLPRDKKKQLSDLIK"
     gene            49461..49883
                     /locus_tag="KRQ43_000189"
     CDS             49461..49883
                     /locus_tag="KRQ43_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBH2740571.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLANIEYFCMTKDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSIFL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENRNKIKNVM"
     gene            49923..50714
                     /locus_tag="KRQ43_000190"
     CDS             49923..50714
                     /locus_tag="KRQ43_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2740572.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMFDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTTLINAIPKVILDGLGVAGTLLPAVGFALLMDMLISKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAMNTLTEGEIDFE"
     gene            50707..51507
                     /locus_tag="KRQ43_000191"
     CDS             50707..51507
                     /locus_tag="KRQ43_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH2740573.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     KVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFLIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            51555..52610
                     /locus_tag="KRQ43_000192"
     CDS             51555..52610
                     /locus_tag="KRQ43_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH2740574.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRANLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGTISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(52770..54716)
                     /gene="feoB"
                     /locus_tag="KRQ43_000193"
     CDS             complement(52770..54716)
                     /gene="feoB"
                     /locus_tag="KRQ43_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH2740575.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKSNTH"
     gene            complement(54734..54952)
                     /locus_tag="KRQ43_000194"
     CDS             complement(54734..54952)
                     /locus_tag="KRQ43_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH2740576.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            55158..55667
                     /locus_tag="KRQ43_000195"
     CDS             55158..55667
                     /locus_tag="KRQ43_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBH2740577.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            55745..55906
                     /locus_tag="KRQ43_000196"
     CDS             55745..55906
                     /locus_tag="KRQ43_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HBH2740578.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            56057..56722
                     /locus_tag="KRQ43_000197"
     CDS             56057..56722
                     /locus_tag="KRQ43_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH2740579.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            56788..58572
                     /gene="pepF"
                     /locus_tag="KRQ43_000198"
     CDS             56788..58572
                     /gene="pepF"
                     /locus_tag="KRQ43_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH2740580.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEKYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            58824..59666
                     /locus_tag="KRQ43_000199"
     CDS             58824..59666
                     /locus_tag="KRQ43_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH2740581.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVMANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     regulatory      59899..59982
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            60562..61239
                     /locus_tag="KRQ43_000200"
     CDS             60562..61239
                     /locus_tag="KRQ43_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740582.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVERI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            61311..63326
                     /locus_tag="KRQ43_000201"
     CDS             61311..63326
                     /locus_tag="KRQ43_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH2740583.1"
                     /translation="MKKYNILKGTLIVLIVSLLAIAGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGEDKLLSLELPEIFSASEVWINGEIVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKDTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKLYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDSSY
                     FMVVLCIICINGSISKIEEDKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFIIVILFSLMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KKFLADVAHDLKAPVSAIQSFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNDFIKEIYENNLPDTQACGVNFETYILEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKVSDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            63376..64056
                     /locus_tag="KRQ43_000202"
     CDS             63376..64056
                     /locus_tag="KRQ43_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740584.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKEISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILTDGDGWTLCKKIRNVTTCPIVYMTYINEEQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            64438..65136
                     /gene="vanR"
                     /locus_tag="KRQ43_000203"
     CDS             64438..65136
                     /gene="vanR"
                     /locus_tag="KRQ43_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HBH2740585.1"
                     /translation="MSGKILVVDDERDIADLIEVYLTNENYIVYKFYSGLDALNCINL
                     NEFDLAILDVMLPGVNGFSLCQKIREKYTYPIIMLTAKDEETDKITGLTLGADDYVTK
                     PFRPLELVARVKAQIRRYKKYSGSLQSGEELSHIFSFLGLELNTQTYECHLNGKALSL
                     TPTEFSILHVLLKNKGSVVNSENLFHAIWKDEYYNKSNNTITVHIRHLREKLGDTVDE
                     AKYIKTIWGVGYKI"
     gene            65172..66287
                     /locus_tag="KRQ43_000204"
     CDS             65172..66287
                     /locus_tag="KRQ43_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2740586.1"
                     /translation="MKKINNFTYRKLRDKYKFIKREKNTEAYLKYKLYIMLAIYTGIV
                     LVLMFMADYTFSNFSNPLVKWLKLRRDVLFFLVFIIGYITIFNFYWKKPWNYLREIIN
                     ATHTIYQQNDELVELSKPLKEIEQQMNQIKMSVLLSQQAVKEAENKKNNLVMYLAHDI
                     RTPLTSVIGYLSLLKEIPNMDNSQKSKYTEVALDKAQYLEKLINELFEITRYNSNQIK
                     INFEKVDLYYMLLQLKDEFYPLLSEKGNRAILKANESLTIKADSEKLARVFNNILKNA
                     IAYSYPNTEIIISAVHKDSKVDIAFRNYGQTIPEEQLSAIFEKFNRLDEARKSDMGGA
                     GLGLSIAKEIINLHGGDITVQSKDEVTTFTISLPTSI"
     gene            66432..67319
                     /locus_tag="KRQ43_000205"
     CDS             66432..67319
                     /locus_tag="KRQ43_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2740587.1"
                     /translation="MELKIEHVTKKFKDKIAVEDVCLTLTPGVWGFLGANGAGKTTLM
                     RIITDIMKPTNGKILYNGKNIYIMGAEYRNLLGFLPQEFGFPQDFSVKDYLEYIAALK
                     DVPPREVKGKINNLLEILTLSDVKNKKIIKLSGGMKRRVGIAQAMLNDPKILIMDEPT
                     AGLDPGERVRFRNFISEFSHNRVVLISTHIVSDIEYISTQNAIMKSGKILDVGTTDKL
                     VKKVEGKVWECLISNRDISKYEMNLRIINQRSEKNNQVSIRYLAEKSQIDNSIAVEPR
                     LEDLYLWLFPEAVYSKEGK"
     gene            67320..68555
                     /locus_tag="KRQ43_000206"
     CDS             67320..68555
                     /locus_tag="KRQ43_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2740588.1"
                     /translation="MRIFYLEIKRVLHSRRTLILLLLALVLSALMAFLPITYEGINYL
                     DNNGKVVELSGLDAIKYKKTIYANNSEISSGVVTPKKLKHALNIWKKTEEKYGKVGSE
                     DFPLDIYSKSILPIRPLLNRLPEAFANSETGFATELSEINTNDLDSFYEQCKTHLNDI
                     MKIERQTSSAQMKAQELYRKVDTPFEIYPGYSKDAFDYIIFYIFILLIICVAITAPTF
                     SGEYQTQSDSILRCTKHGHTRLAFTKILALFSIFIVMFVVCISIHLAISDLAFGTECL
                     KTSFQMLFSVISLVNINLLQAQILIAIGGLISILAMVSLTLFLSAKCKDSLTSMLIAF
                     SICLIPMGIGVSWIGYLLPPGGIGLKISLLYQMTSFNFLHLGGMSFWTPHIILFFSVI
                     EIPIFIFLAIRTYCKHQVS"
     gene            68937..69854
                     /gene="pstC"
                     /locus_tag="KRQ43_000207"
     CDS             68937..69854
                     /gene="pstC"
                     /locus_tag="KRQ43_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBH2740589.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGILSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            69856..70680
                     /gene="pstA"
                     /locus_tag="KRQ43_000208"
     CDS             69856..70680
                     /gene="pstA"
                     /locus_tag="KRQ43_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBH2740590.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVIIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            70699..71463
                     /gene="pstB"
                     /locus_tag="KRQ43_000209"
     CDS             70699..71463
                     /gene="pstB"
                     /locus_tag="KRQ43_000209"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBH2740591.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            71491..72144
                     /gene="phoU"
                     /locus_tag="KRQ43_000210"
     CDS             71491..72144
                     /gene="phoU"
                     /locus_tag="KRQ43_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBH2740592.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            72302..73171
                     /locus_tag="KRQ43_000211"
     CDS             72302..73171
                     /locus_tag="KRQ43_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH2740593.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGNYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            73258..74694
                     /locus_tag="KRQ43_000212"
     CDS             73258..74694
                     /locus_tag="KRQ43_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBH2740594.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            74742..75569
                     /locus_tag="KRQ43_000213"
     CDS             74742..75569
                     /locus_tag="KRQ43_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH2740595.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    75870..76132
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            76208..78874
                     /locus_tag="KRQ43_000214"
     CDS             76208..78874
                     /locus_tag="KRQ43_000214"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBH2740596.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKAHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKVKKEKFEEMIKSVEERLTNLESKIK"
     gene            79299..80009
                     /gene="rgaR"
                     /locus_tag="KRQ43_000215"
     CDS             79299..80009
                     /gene="rgaR"
                     /locus_tag="KRQ43_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HBH2740597.1"
                     /translation="MFRVVICDDEKIQRSILKEFTKKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            81055..82086
                     /locus_tag="KRQ43_000216"
     CDS             81055..82086
                     /locus_tag="KRQ43_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH2740598.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALLMKVADVVRDCL
                     DIEDNNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            82219..83517
                     /locus_tag="KRQ43_000217"
     CDS             82219..83517
                     /locus_tag="KRQ43_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBH2740599.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(83631..83876)
                     /locus_tag="KRQ43_000218"
     CDS             complement(83631..83876)
                     /locus_tag="KRQ43_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH2740600.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            84024..84890
                     /locus_tag="KRQ43_000219"
     CDS             84024..84890
                     /locus_tag="KRQ43_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBH2740601.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(84894..85430)
                     /locus_tag="KRQ43_000220"
     CDS             complement(84894..85430)
                     /locus_tag="KRQ43_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HBH2740602.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(85620..85823)
                     /locus_tag="KRQ43_000221"
     CDS             complement(85620..85823)
                     /locus_tag="KRQ43_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH2740603.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            86114..86878
                     /locus_tag="KRQ43_000222"
     CDS             86114..86878
                     /locus_tag="KRQ43_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH2740604.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKYDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKKTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            87267..88580
                     /gene="prdC"
                     /locus_tag="KRQ43_000223"
     CDS             87267..88580
                     /gene="prdC"
                     /locus_tag="KRQ43_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HBH2740605.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     gene            88749..88911
                     /locus_tag="KRQ43_000224"
                     /pseudo
     CDS             88749..88911
                     /locus_tag="KRQ43_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011020315.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            89381..91141
                     /gene="prdR"
                     /locus_tag="KRQ43_000225"
     CDS             89381..91141
                     /gene="prdR"
                     /locus_tag="KRQ43_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HBH2740606.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            91570..93450
                     /gene="prdA"
                     /locus_tag="KRQ43_000226"
     CDS             91570..93450
                     /gene="prdA"
                     /locus_tag="KRQ43_000226"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HBH2740607.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            93531..93815
                     /locus_tag="KRQ43_000227"
     CDS             93531..93815
                     /locus_tag="KRQ43_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740608.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            93853..94578
                     /gene="prdB"
                     /locus_tag="KRQ43_000228"
     CDS             93853..94578
                     /gene="prdB"
                     /locus_tag="KRQ43_000228"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:94303..94305,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HBH2740609.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            94658..95416
                     /gene="prdD"
                     /locus_tag="KRQ43_000229"
     CDS             94658..95416
                     /gene="prdD"
                     /locus_tag="KRQ43_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HBH2740610.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            95431..95898
                     /locus_tag="KRQ43_000230"
     CDS             95431..95898
                     /locus_tag="KRQ43_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBH2740611.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            95916..96398
                     /locus_tag="KRQ43_000231"
     CDS             95916..96398
                     /locus_tag="KRQ43_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBH2740612.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPAVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            96418..97425
                     /locus_tag="KRQ43_000232"
     CDS             96418..97425
                     /locus_tag="KRQ43_000232"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HBH2740613.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            97545..98426
                     /locus_tag="KRQ43_000233"
     CDS             97545..98426
                     /locus_tag="KRQ43_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH2740614.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            99094..99729
                     /locus_tag="KRQ43_000234"
     CDS             99094..99729
                     /locus_tag="KRQ43_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH2740615.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            99913..100482
                     /locus_tag="KRQ43_000235"
     CDS             99913..100482
                     /locus_tag="KRQ43_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH2740616.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            100560..100697
                     /locus_tag="KRQ43_000236"
     CDS             100560..100697
                     /locus_tag="KRQ43_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740617.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            100694..102469
                     /locus_tag="KRQ43_000237"
     CDS             100694..102469
                     /locus_tag="KRQ43_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2740618.1"
                     /translation="MMVMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDVCRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            102894..104201
                     /locus_tag="KRQ43_000238"
     CDS             102894..104201
                     /locus_tag="KRQ43_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBH2740619.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDEKLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            104529..105068
                     /gene="hpt"
                     /locus_tag="KRQ43_000239"
     CDS             104529..105068
                     /gene="hpt"
                     /locus_tag="KRQ43_000239"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH2740620.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            105446..>105927
                     /locus_tag="KRQ43_000240"
     CDS             105446..>105927
                     /locus_tag="KRQ43_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HBH2740621.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGATGATGA
                     NGVTGATGPTGNTGATGPTGSIGATGANGVTGATGPIGATGPTGAVGATGPDGLVGPT
                     G"
BASE COUNT        42588 a        11391 c        19007 g        32941 t
ORIGIN      
        1 ttttatattt aagtaaatgc gtgtaaaatg aatataaagt ttttgaaata taaagttttt
       61 gtatctaaaa tattttattt gtaaaatagt aattaattat tgtaagctat aatatgagag
      121 tattatggtt aatgtgaatt ttaaagatat tattaaagat ataaattaga atactattaa
      181 acggataaat ggaggagtta ttatgtctaa gatattagta gtagatgatg agttagatat
      241 gttaaagttg attgaaaatg tgttgaaaag agatggacat gaagtaaagg taattagtga
      301 tgtagaaaag gctatgaaca tggattttaa ttattttaat ctaataatat tagatgttat
      361 gatgcctaag atggatggtt ttgaagtatg taaaactata agaaataagg ttgattgtcc
      421 aatactgttt ttgacagcaa aaaatatgga aagtgatatt atgtacggtc ttggcatagg
      481 tgcagatgac tatataacca aaccttttgg tgtaggagaa ttaagggcta ggataactgc
      541 tcatttaagg cgagaaagta gagaaaaaaa gaatttatta actatctcaa atgttcaatt
      601 taacttttta ggcaaagaag tttcaattga tggtaaaaaa attaatttta ctaaaagtga
      661 atatctaata tgtgaatttc tagcaaaaaa taagggacaa gtattttcaa aagaaagaat
      721 atatgagtcg gtatatggtt ttgatggaga aagtgatata agtactatca cagagcatat
      781 aaaaaatata cgaagcaaat taaaacaata tgatatttat acaatagaaa ctgtatgggg
      841 gatagggtat aaatgggtgt aataagtata agtgttgctt agtgaaaata ttatatatat
      901 ctacaaaatg tttgtaaaat attaatctat atattaaaat ttaatttata gattaatatt
      961 ttttgtaaat gacaaaattg taaggtattt tgttataaaa tattaagatt catagtgtat
     1021 actaataata tagtatttag tataaatctt gagcaaagga tggttatttc taatggatag
     1081 actaaagaat attagaaaga gtttactaca gtatacattt ttatttttgt taataggtat
     1141 aacaatttac ctagtgttta aaacattgga tattaaaatg ctatcaaatg ttatggttat
     1201 ggtagataag aagtttttat tcataggtgc tttggcaata atgtgtcaca taatgcttga
     1261 aggagtagta atgaagataa ttatagaaag cactcacaaa gttaatatta gatttattgg
     1321 ttttaagcta gccattatgg gattttatta taatttaata actccttttg cttcaggaag
     1381 ccaaccagta cagatatatg tacttaaaaa atgtaaaatg ccacttagta aggcaagtgc
     1441 agttgttacc aataagtcta ttattttcca aatagtggtt actttttatt gtacaatact
     1501 tgtattaatg aattttgcta tgttagaaaa acaaatgaaa atgattatgc ctctagtgtt
     1561 tctagggata gccattaatt catttgtctt aattatgata atattagtta ttttaaaccc
     1621 taaaaaaata aaatatttta tgagaattac tataaagcat ttatcaaaaa ttaagttttt
     1681 aaaattttta gataataaga ttgaatccat agaaagtttt atagatgatt atagtaaagc
     1741 aataaatttt tttgcaaaga ataaaaaggt attaatttca actataatag taacttttat
     1801 tcaattaagt gcttacttta gtgtttcatt ttggatatat aaagcattta atttacaagg
     1861 ttatagctat atttatatac tgacattaca agcattttta tatatggcaa tatctccaat
     1921 accaacacct gggaatgtag gagctaatga attagccttt ttcactatat tcaaatcagt
     1981 attccctcaa cctttgatgg gatatgcagt atttttatat ggtggattta tgtactattt
     2041 aattctgatt ggaagtggaa tatttactgt aattactcac tatagaatga aaaatagaat
     2101 tggcagaaat attgttttaa gtgaaaacta aataagttta aagaatatat attgagtata
     2161 ttaaaaaata tgtcataaga actagaatat tttaattaaa tggttgaaat ataaagatta
     2221 ttatgacata ttttttttga aatttaagag gaattgtgag aaaattgttg aatttaatag
     2281 atagtattgc aaaatattta tgattttgca tattataaaa acactcatta tctttaagat
     2341 aaattttact tatcagggga taaatctaag gggggaattg tatggagaaa aaaattttaa
     2401 cagtttgtcc atactgtgga gctggatgcc aattatatct agtagtaaaa gataataaga
     2461 tattaagagc tgaaccggct aatggtagaa caaatcaaga aagtttgtgt ttaaaaggtc
     2521 gttatggatg ggattttcta aatgacccta aaattctaac acctaggcta aaaaagccaa
     2581 tgataagaaa acaaggtgta ctagaagagg ttgaatggga tgaggctata aactatacag
     2641 cttcaagact aaatgaaatt aaagaaaaat atggacctga ttctattatg ggaacaggtt
     2701 ctgcaagagg acctggtaat gaagcaaact atataatgca aaaatttatg agagctacaa
     2761 taggaactaa taatgttgac cattgtgctc gtgtatgaca tgcaccatct gtagccggtc
     2821 tggcttactc attaggtagt ggtgcaatgt ctaattctat accagagata gaaaatgcag
     2881 atgttttatt tatatttgga tataatggag cagattcaca tccaatagtg gcaaatagaa
     2941 tagtaaaagc taaaaaaaat ggtgctaaat taattgttac tgaccctaga gtaactgaat
     3001 ctgcaagaat tgctgatata catctaccta taaaaggtgg aacaaacatg gttttagtaa
     3061 atgcttttgg aaatgtatta atagaagaag gtctttacaa taaagaattt gttcaaaatc
     3121 atacacaagg atttgatgag tataaagaaa ttgttaaacc atatacagct aaatatgctg
     3181 aaaagattac aggaatccca gaagagctta taagaaaagc tatgagagaa tatgcaaaag
     3241 ggaaaaaagc tatgatactt tatggaatgg gtgtctgtca atttggtcaa gctgttgatg
     3301 tagttaaggg acttgcatca attgctctac ttacaggtaa ttttggtaga gaaagcgttg
     3361 gaataggacc tgtacgtgga caaaataatg ttcaaggagc ttgtgatatg ggagctcttc
     3421 ctaatgtata tcctggctat caaaatgtaa ctgatgataa gataagagaa aagtttgaaa
     3481 aaacttgggg ggtaaaatta tctcctaata atggttatag tttaactcaa gttccagact
     3541 tagtactaaa agagaaaaag cttaaagctt attatatatt tggagaagac ccagtgcaaa
     3601 gtgacccaga tgcatcagaa gttagagaag cattagatga attggaattt gtcattgttc
     3661 aagatatatt tatgaataag acagcacttc acgctgatgt tatacttcca gctacttctt
     3721 ggggagaaca tgagggagta tatacatgtg cagatagagg attccaattg atgagaaaag
     3781 ctatagagcc acaaggagat gtaaaaccag actggcaaat tataagcgaa atttctacag
     3841 caatgggata tcctatgaat tataaaaata ctaaggaaat atgggacgaa cttagacaat
     3901 tatgtccaag tttcttaggt gctacttatg aaaagataga aactcaagga tgcgttcaat
     3961 ggccttgtaa gagtgaaagt atggaagata aaggaactat gtatctgtat gaaggtcaaa
     4021 agttttctac tcctaatggt aaaggtaatt tgttcgctgc tgaatggaga ccccctatgg
     4081 aagttgaaga tgatgaatac ccatttagtt tatgtactgt aagagaagtt ggacactatt
     4141 cagtaagaac aatgactggt aattgtagaa cacttagttc attagaagat gaaccaggac
     4201 gtgttcaaat aaattctaat gatgctgaaa aattaggaat tgaagatgat gaattagtta
     4261 gaattagttc aagaagagga agtgtaataa caagagcaac agttactgat agagttaagg
     4321 aaggtgcaac atatatgact tatcagtggt gggttggagc ttgcaatgaa cttacaatag
     4381 caaatttaga ccctatatct aaaacaccag agtataaata ttgtgctgtt aaacttgaaa
     4441 aacttgaaga ccaagaatta gcagaaaaat gtgtaagaga agagtatcaa agtttgaaag
     4501 acaaaatgac agctacaaat atctaatgat ttattagatt taagatttat aaaaggcaga
     4561 aaggctaata ttttatgaac aatatatact caaaaactaa attacaagaa aatagtaagg
     4621 ataaagtttt tgaaaatagt tatagtctag tggactacaa atatttaaat tcttttaatg
     4681 tagaagtaag caaaataaat gaacatgaag tatcaataga taatgaagaa ataattgcag
     4741 aatatccact tagttttatt ttaaatgata aatatgtaaa tacattttta tgtaccccat
     4801 ataatttaga ggaacttata gtaggattct tgaaaacaaa aggatacata gaaaacaaaa
     4861 aaagcttatt aaaatttgag ataaatgaga gtgaacgttt tgcaaaagta actattcaag
     4921 agaaacaaaa aaatcaagat gagcaaatta tatttttaaa ttcactagac tatataacat
     4981 gtgcttctgt aaagagcaat ataaaaataa attatgatac gatttacagt ataatggata
     5041 gaaatttaaa ttcatcagaa ttatttaaaa atactggtgg ggtacatagc gtatctgtat
     5101 ttaattttga taaaaaaata gtcacttgtg aagatgtagc aaggcataat gcaatggata
     5161 aggctattgg attttgtgtt ttaaatgaca taacattaaa agataaaatt gtggctgtaa
     5221 gtggaagaat atcattggaa atgatattaa aagcagctat gactcaaatt cctattgtag
     5281 tatcaaaatc agcaccgact aatttatcaa tagagctttc taaaaaatta aatataacgc
     5341 ttattggatt tgtaagagga agacggatga atatttatgc aaatccacag agagttatca
     5401 aaaagtgaga ataagtatat gtgtactaaa aaagaagaac aaaaatgttc aaagtgtgaa
     5461 atctgtggag tattaattga cgatactgat aaggtgtata ataacacata caatttgtgc
     5521 aaaaaatgta aacgaaatat aagtactgag aaaatagtga aatatataaa tatatatgat
     5581 gaaagtaagt agacatatga tgaaagtaac tagagggttg gaaatataca aattgaaagg
     5641 tgggataata tgaaaaataa aataggctct tttgtaatag cggacccaaa caaatgtaca
     5701 ggttgtagag cttgtgaagt agcttgtttt acaatgcata atcagcataa taatgtgggt
     5761 tatacagttg gaacagttga tatacctgtt atacctagac tttatttagt aaaaggtgac
     5821 aatttctgta tgccaataca gtgtagacat tgtgaagatg ctccttgttt aaactcatgt
     5881 ccacaaaaag ctatagtcaa agaaaacaat attatgtctg taaatgaaga aaagtgtata
     5941 ggatgtaaaa cttgtctgct agcatgtcct tttggagcta tagacttact tccacaatat
     6001 gaagatggta aagaagtaga acaagtaatt ttagatgaaa ataagaagat agcttataaa
     6061 tgtgacttat gtaaagacaa tgaaaaaata gcttgtataa gtgcatgtcc tcaggaagca
     6121 ttaaaacttg ttactccaat agatgacaaa aaagctaaga atagacaagc tgcacttagt
     6181 ttattgttaa caaataaata aaggatacag gggtaggtga cgtttatgat aataaatata
     6241 gataaggatt tatgtactgg atgtagagaa tgttcaaagg tctgtccagt aaatgctatt
     6301 gaaggtgaag agggaaagcc acaagagata aatttagata gatgtgttat gtgcggtcaa
     6361 tgtgttcaaa cttgtaaatc ttatgcctca gttatagatg aaggatttga gtttttacaa
     6421 gagaaaaaac aagaaagaga gataccagag tctataaatg aacctatatt tgcagcatac
     6481 aatgtatgtg atatagataa ggtaaagaaa gctttaagtg acccaaatgt attcactatg
     6541 gtccaatgtg caccagcagt tagagttgct ttaggagaag atttcggata ttatttagga
     6601 tacttaggtg ctggaaaaat ggcagcagca cttagagctt taaattttga tagagtctac
     6661 gatactaatt ttgcagcaga tttaactata atggaagaag gtagtgaatt aattaaaaga
     6721 gtgacagaag gtggaactct tccaatgttt acatcttgtt gtccagcttg ggtaaaattc
     6781 atggaaaaaa attatcctaa attaactaat catttatctt cttgtaaatc acctcagcag
     6841 atgggtggtg caatatttaa aacttatggt gcagagataa ataatgtaga tgcatcaaag
     6901 atatttagtg tttctataat gccatgtaca tgtaaaaaat atgaatgtga tagagaagaa
     6961 atggattcta gtggatatag agatgtagat gtagtattaa ctactagaga actagcttat
     7021 ttaataaaag acatgggaat tgattttaaa aatttaagag aagaaaaatt tgatagtcct
     7081 ttaggtagtt atagtggagc tggaactatc tttggtgtta ctggtggggt tatggaagct
     7141 gctataagaa caggatatga gcttataact ggagaaagta ttcctgatgt agaagtaaaa
     7201 caagtaagag gagaaaatgg ttttagaaag tcaactatta aaataggaga cttagactta
     7261 agagttggag tagtaagtgg attaaaaaat gtaataccag tgcttgaaga cttggaaaaa
     7321 ggaaaattag atgtagattt tattgaagtt atgacttgtc ctgttgggtg tgtaagtggt
     7381 ggaggtcaac caaaaatttt actagaagaa tataaggaat tggcttatga aaatagaaca
     7441 aaagcaacat acgtgcatga tgaacattta gcaattagaa aatctcatga gaatcctgat
     7501 attaaaaaac tgtatgatga atatctggta gaaccattag gagaaaaatc tcatcatcta
     7561 ttacacacta catattgtat aggaaaggaa gtggctaagt gatgaactat tttgttatag
     7621 cagaccctga taaatgcata ggatgtagaa cttgtatgat aggatgtgta gttgcacatt
     7681 cagatgaaga tattttttac caaaatccag atgaaataaa ttttaatcca aaactttctg
     7741 tcataaagac aaaagaagta agtgctccaa tacagtgtag acattgtgaa gatgctcctt
     7801 gtgcaaaggc atgtccaaat ggtggtatag ttagggttgg gaacacaata aaaataaatg
     7861 aagaaaattg tataggatgt aagacttgta tgttagcatg tcctataggt gcaatagaca
     7921 tagttacatt aaaagatgta gatgaaggaa agctttgctt tagagaaaga atgacagcaa
     7981 ataagtgtga tttttgtata gaatcgccag aagggcctgc atgtgtaaat gtttgtccaa
     8041 ctaaggcatt tactatagtt aaggatgagg atatagatag taaagttaaa aataagagaa
     8101 aattagctat attgtaatat aaaaaagatg gagttttatt tatgattaaa agctccatct
     8161 tttttattat aatatttata tatctaaaaa tcaattattg cattagttta tctaatcttt
     8221 ctttattcaa ttttttcatt cctatagaag ttataataag taaagtatag gcaattataa
     8281 ctgataaaat tataatagac caagaaaatc tgtatccaaa attatcaact aacaatccaa
     8341 ataatgttga acctaatgca aatcccactg caaaaattaa ttgtacgatt ccatatatgc
     8401 taccaaactc cttttgacca aagaaagagc cagttaaata agcaggacca atcatataag
     8461 caaatacaga aagacctttc aaaatggcaa atacaaatgc aaaagtagaa gatttatcta
     8521 ccaatagtaa tgataaagtt gctataagaa ccaatacaaa agatataata agtggctttg
     8581 tttgaccgaa tttatcaaac aataatcctc caaataaatt accaatgaga gcaaataaag
     8641 caaatgtgga gcctactgtt cctattagaa taggatttag ataatttcta agataagttg
     8701 gatattgtac ggataatgat gaaacatata taccaacaaa tataaatcca atagtcataa
     8761 tccaaaaata tttaattttt ttagcttctt ttaatgtata accccatact gaaggagaaa
     8821 ttgtatcaga tgctttctct tttttacctt tagattttac cttttcatta atatctttag
     8881 gcatcctgag tatgaataat attacaggta taccaactat taatgctata attccaaata
     8941 ttagataaga atgactgtat ccttgagttg ctaataagcg aactgcaagt ggttgtagaa
     9001 atatactacc aatagaacca ccagcaaaag caaagcccaa agcttttcct ttgctttctt
     9061 catcaaacca agcacttatt aaaacaggta ttcctatagc agatataatt gtagcgccaa
     9121 tttgaacaat acatgataca gtgtaaaatt gccatagttc agtacatata gaaaaagtag
     9181 caaaagcaat actagaaatt atacaaccta ataaatatag tatcttaata ttgactttag
     9241 aaaataatac acctataaaa ggtgatgcaa ttgctgaggc aatagtacca atagtgaata
     9301 ttagagaaaa agaagctaaa ctaaagcctt ctccttctac aacataactt ataaattgag
     9361 gctgtatact tgctacaata ctaaatggaa cagcttgtat taacatacaa ccaagtacta
     9421 taacccaagc atttgaaaag tttttaatgc taaatttatt gtttagtaat gtattcatgg
     9481 tatctctcct ttaggttatg atttgtagat attaatctaa ttattctaat tttatatatt
     9541 agttttggat agcctaacta tttaaatgta atttgggtat taatataaaa attaactata
     9601 aaaattgatt attttaaatg tatggggtaa attaaagtat ataaataaat gaaaggatgg
     9661 ataaaatgtc atttgaaaaa ataaataata ataacctaga taaaatacac aataggaagt
     9721 gtattatgct tgtaaacttt aataaaaaag aattatcatt aattaaaaac gtaagtaact
     9781 ttgctggaat aagagaccat ataatcttaa gtgaaaaaaa cggagagaat ataataagag
     9841 acattttaga tggaaatata tcaagtgaat gtgaaaatgg gattaagagt aagtctgtaa
     9901 tatttaataa cactccaagc acacaagtaa atgcattttt agaaggtcta aaaaaagtga
     9961 gaataaatag accttttaca gctatggtaa cagagacatc tattgattgg acattgaata
    10021 atttaataga aaatttagtt caagaacgta atgctatgtc tttaggaaaa acaattgaac
    10081 ataagtaaat ttaagatatc ttatagtaat tttaactaat gtacattgag tatcatatta
    10141 tattttagaa tataaaattt taaatgtggg tagatagagg agatttgaga tgaaagtttt
    10201 atttacaata aattatggaa aagaaaaatt tgataaaata agagaattag gctatgatgt
    10261 catacattac tctgaagata gtattgaaaa taatgaggat gtaaatacag cagatgtact
    10321 agttacatac aatccatttg agagattaga tatttctaag atgaaaaatt tacaatatat
    10381 acagacaact agtgtaggta tagaccaact tccaaaagaa gaggtattga agagaaatat
    10441 taagatagct aataatagag gcggatatag tgtacctatt ggtgaaagta ttgtattgta
    10501 tattttagaa atatataaaa atagtgcaaa attttttaaa caacaacaaa ataaagaatg
    10561 gaagatggat ttttctgtat cagaattgta tggacaaaga gttggatttt taggaacagg
    10621 tactatatct tcagaagcag caaaacgatt aaaagctttt ggtgtagaaa tatggggtgt
    10681 caatactgat ggaagtagta aaaaatactt tgataagtgt tttgctactg aagatatgaa
    10741 tattgtattt gaagaatgtg atatagtagt tgtagcaatg ccttctacaa aaagtacaga
    10801 tggaatagta aacaaagata tgtttaaact tatgaaagat ggttctgtat ttataaatgt
    10861 aggtagagga aatacagtta atcagaaaga tttagaagaa tgtgtagaga aatttagagg
    10921 ggtagcacta gacgtatttg aaagtgaacc tttaaacaag gacaataagt tgtgggagtg
    10981 cgaaaatgtc atagtaactc ctcataattc ttgggtgtca gataaaaaca aagagagaac
    11041 atttaatatg gtttataata atttgaaaca ctatataatg gagaataaac ctgtagataa
    11101 tgttgtagac atatcaagag gctattaaaa ataaaaaatt ttgataaaaa taaaaactct
    11161 tattagtcgt attaaagata ctaataagag ttttttttgt aataaattta aagtcaaaaa
    11221 agtgatatac taaaaaatat ataaatagga gataattaat tatagggaaa tttcaaaata
    11281 atttaatttt aaaaatatga agaggtgcaa aaagtgagcg taaaagatga aattaataaa
    11341 cttatagaga caataaacta ccataatgaa aggtattata atcaagatag cccagaaata
    11401 tcagattatg aatacgataa gttaatgaag gagttaattt ctttagaaga agaacatcca
    11461 gaactaaaga gaattgattc tccaacaaat agggtaggag gtaagccatt agataaattc
    11521 aatcaaattg tacataaaac tcctatgttg agtttatcaa atgctttttc agagcaagat
    11581 ttgagagatt ttgataagag agttcaagaa tatgtgggag aaaatgttga atatgttgtt
    11641 gaatttaaaa tagatggtct ttctgtaggt ctaacttata acaatggaga gtttgaaaaa
    11701 ggagcaacta gaggagatgg agttgtagga gaagatattt ctcaaaactt aatgacagta
    11761 aaaagcatac ctcttaagat aaatgataaa aaagaactaa tagttagagg agaagtatat
    11821 atatcaaaag ataattttag aaaagtaaat gaacaacaag aagaacaaga acagccatta
    11881 tttgctaatc caaggaatct tgcagctggt tcattgagac aattagaccc aaaactaaca
    11941 gcaaagagac cattagatat atttgtattt aatatggaaa atatagaaga atatgattta
    12001 gaaagtcaca gtgaatcact agagtactta gaaaaactag gattttcagt aagtcagagt
    12061 tataaagttt gtaaaagtat agatgaagtt attgagcata ttgaatactg gacagataac
    12121 aggggtaatt tagactacga aatagatggt atggtaataa aagtaaacaa tataaaacaa
    12181 agagacgaaa tgggatatac agccaaaagt cctagatggg caattgcata taaattccca
    12241 gcagaaaaga agaaaactaa aatagtagat ataatagtag aagttgggag aactggtaca
    12301 ataacacctt cagcaattct tgaaccagtc agacttgcag gtactactgt aagtagagct
    12361 acacttcaca atgaagatta tataagagaa aaagatataa aaataaatga tacagtatta
    12421 gttcaaaaag caggggacat aatacctcaa gttttagaag ttataaaaga ggaacgtact
    12481 ggagatgaaa tagattttaa aatgccagaa aagtgtccag tttgttcaga gccaacaata
    12541 agattagaag gagaggctgc tgtaaaatgt atcaatatgt cttgcccagc ccaaataaga
    12601 aggggaatta tacactttgt gtcaagggat gcaatgaata tagatggatt gggagaatct
    12661 ataattacac tgctattaaa tgaaaaaatt attcaagatg tatctgattt atattatata
    12721 aaaaaggaag atgtagtcga cctagagaga atgggcgaaa aatctgctga caatttaata
    12781 aattcaattg aaaaatcaaa agaaaatgat ttatggagac ttataaatgg attaggtatt
    12841 aaatttatag gagttaaagc agctaagata cttgcatata actttaagga tttagatgaa
    12901 gtaatttctg caactagtga gcaactagaa gaattagagg aatttggaag tataatggca
    12961 aacagcgttg tcgagttttt taaggaagac aaaaatatga acgttataaa caagttaaaa
    13021 aatgtaggag taaatacaaa atcattggat aatacaggtg aaaaagtaga aaaaatattt
    13081 gaagggatga aaatcgtatt gactggtaca cttcctacat taaaaagaaa tgatgcgaaa
    13141 gatatgatag aaaaaagagg tggaaaagct acatctagtg ttagtaaatc gacaacattt
    13201 gttttggcag gtgaagaagc tggttctaaa cttactaaag caaatgattt aggaattaaa
    13261 gttatagatg aagagagatt tttagaatta ttaaagttat catcgaaaga tgaagtaaaa
    13321 gctgtattag agagttaaaa agtcgcttaa tttagtagaa aactactata attaatgata
    13381 gaatagttca gtaagctaat aagattacga aaaatgacaa taattaatat ttgacaaaat
    13441 taaaaattat aaaaataaat ttataaaaaa taaaaaatat gagaaaggat ataaaaaatg
    13501 accagaagtt atgatagaag taacgaacag ataagacctg taaagataac tagagattat
    13561 acaaagtatg cagaaggttc tgttcttata gaaatgggag agacaaaggt tatatgcact
    13621 gcatcagtgg aagaaaaagt tcctcctttt ttaagaaata gtggtactgg atggataaat
    13681 gctgaatatt ctatgctacc aagagcaaca caacaaagaa agataagaga tgcatctagg
    13741 ggaaaaattg atggaagaac acaagaaata cagaggttaa taggaagagc aataaggtct
    13801 gttgtagact tgaataaatt aggagaaaga actatttggg tagattgtga tgtgattcag
    13861 gcagatggtg gaactagaac tgcatctata acaggggcat ttgtagcagt tgcagaagca
    13921 atatataaat tatataaagc aaagacaata aaagagatgc caataacaaa ttttgtatct
    13981 gcaattagtg ttggtattgt aaatggaata cacatgctag atttatgtta tgaagaagat
    14041 tctaaagcac aggtagatat gaatataata atgactgata agtgtgagtt tgtagaagta
    14101 caggggacag gagaagagaa acctttttca agagcagatt taaatttatt gttagagtta
    14161 ggcgaaaaag ggaataaaga attaataagg cttcaaagag aagctttagg tgaaatagca
    14221 gatgagatat tgggtatgga ttatggtaat gaagtagtga ttgctactaa taatgctcat
    14281 aagctagaag aaataggtga aatcttaaaa gattttgaat ataaagtgta ctctttaaaa
    14341 gatgttgatt tagcaggtat agagatagta gaagatggaa aaacatttga gcataatgcg
    14401 ttgataaaag ctagagcaat agcaaaaaag actaaactta tagcaatatc agatgattct
    14461 ggcttagaag tagatgcttt aggcaaaaaa cctggtgttt attcagctag atatgcagga
    14521 gaacatgcaa cagatgaaga aaatagaaaa aaactgttaa aagctatgca aaatgtacca
    14581 atgagcaaaa gaaatgcaag attcgtctct gcaatagcag tagtttttcc tgatggaaaa
    14641 gaatttgtag taagaggaat ttgtgaagga atgataggat ttgaagaaaa aggtaaaaat
    14701 ggttttggat atgatagctt atttatagta aaaggatatg ataagacttt tggtgaaata
    14761 cctagtgtta taaaaaattc aatcagtcat agagcaaacg cactaaaact tatgaaacaa
    14821 gagtttataa aaagggtagt gaagtaatga aaataggcat agtaagcgac acacatatga
    14881 tgattaaaaa tatggaaaaa acaataccat atttgaaaga atgtgaccta ataattcatg
    14941 caggagataa ctttactgat tcaagatata ttcatagcat gactaatgta ggtattattg
    15001 cagttaaagg taattgtgac tttgatgctg ttgaggaaga agttgtcttt gaagtggcaa
    15061 ataaaaccat attcttatgc catggagata agtatggtgt aaaatatgga actaatatgt
    15121 tagaaaaaaa ggcaactgaa gttgatgctg atatagttat atttggccat acccataccc
    15181 catttagaga aattaaagat ggtgtacttt acataaatcc tggaagcact tcacttccaa
    15241 gaggagtatc gtataaaagt tttgtcatta tggatataga agaagatgac ataaaaattg
    15301 aagaaatacg catataaagg tgtatttatc taaaaaaatg gcaaaaaacg ctcaaaaaat
    15361 taaattttat caaataagta caacgatatt aatggaacac ttgtaaataa aaaaacttat
    15421 gtgatataat taagtggttg aattataaat agaatgaatt ataataccgt tatcgggtat
    15481 tacataaata tcactaggag gattagaagg atgaaagcag aactaattaa aaaagagggt
    15541 aataaagtta ctttaaaaat aacagtagat aacaataaat ttgaagcagc agtaaataag
    15601 gcttataata aaagcagaaa taaatacaat atacctggat ttagaaaagg taaagctcca
    15661 agaattgtta tagagactca atatggaaaa ggtatattct acaatgatgc tatagaaata
    15721 ttattcccag aagtttatcc agaagctatc aaggaattag acatagaccc aatagacaat
    15781 ccagatttag atatagaaga aataagtaaa gataatgggt tggttatggt tcttaatgta
    15841 gaagttaaac cagagtttga attaggaaac tacaagggta tagaaatagc taaggttgag
    15901 aatactgtaa gtgacgaaaa tgttgatgct aaactacaag aaatggttga aaaaaatgcc
    15961 agattagtaa gtgtagaaga caaagcttta gaagatggag atacagctat aatagacttc
    16021 gaaggttttg aaaatggtgt agcttttgat ggtggtaaag gtgaaaatta taacttagtt
    16081 ataggttcaa acacatttat accaggattt gaagaacaat tagtaggtaa aaaagctggt
    16141 gaagaagtag aagttaatgt tactttccca gaagaatatc actcacaaga tttagctgga
    16201 aaaccagttg tatttaatgt aaaaataaat gatgtaaaag taaaagaatt atctgcactt
    16261 gatgatgaat ttgctaaaga tactagtgaa tttgattctt tagatgaatt aaaagcagat
    16321 gtaagagcta agttagaaga agaagctaaa aatagagcag atgcagaaac tagaaattca
    16381 gtagtagaaa aagttgctga aaatacagaa atagaaatac cagaagttat gatacaacat
    16441 caaatagata atatgttaaa tgaacttaac taccaattac aatatcaagg atttggatta
    16501 caacaattac tagagatgac tggtagaact atggaagaat taagagaaga gagaaaagaa
    16561 gatgctaaaa aattagttaa gtcttcttta gtattagaag caataactaa agctgaagga
    16621 attgaagcaa cagaagaaga atttaaggct gagttagaaa aaatggcttc tgcttacaat
    16681 atggaagtag aaaaaataga agcttcttta agagatgctg acaaagaaga tataaaaggt
    16741 caaataaaaa taagaaaaac aatagattta ttagttgata atgcaacaat agcttaataa
    16801 aataaacgct aactaatata gttgacgtta tgaaatgttt agtatataat gatgtgcaaa
    16861 tataatttag ttaaatgcgt ataataattt acagtagctt aaaaaagcta ctgtaaatta
    16921 tatagaataa agggggtatg aaaccatggc attagtacct gtagttgttg aacaaacagg
    16981 aagaggagaa agatcttatg atattttttc tagactatta aaagacagaa taatcttctt
    17041 aggagatcaa gttaacgatg ccacagcagg gcttatagta gcacagctat tatttttaga
    17101 agctgaagac ccagacaaag atatacattt atatataaat tctccaggag gaagtataac
    17161 ttctggaatg gctatatatg atactatgca atacatcaaa ccagatgtaa gtactatatg
    17221 tataggtatg gctgcttcta tgggagcatt cttgttggca gcaggagcaa aaggaaaaag
    17281 actagcacta ccaaatagtg aaataatgat acatcaacca ttaggtggag ctcaaggtca
    17341 agcaacagat atagaaattc atgcaaagag aattttaaaa ataaaagaaa ctttaaatga
    17401 gatattatct gaaagaactg gtcagccatt agaaaaaatt aaaatggata ctgaacgtga
    17461 taacttcatg agtgcactag aagccaaaga atatggttta atagatgaag tatttacaaa
    17521 gagaccgtag atagagagag gtgttaatat gtctaaatat gaagaaaaac gacaattaaa
    17581 gtgttcattc tgcggtaaaa atcaagatca agtaagaaga ttaattgcag gtccaaatgt
    17641 atatatttgt gacgagtgtg ttgaactttg tgacgaaatt attcaggaag aaatagaaga
    17701 tactatagat gaagatacta catctttacc aaaaccaaag gaaatgatgg agattctaaa
    17761 tgattatgta ataggtcaag aaaaagctaa aaaagcttta tcagttgcgg tttataatca
    17821 ttataagaga atatacagta aaaaatctag tagtaaggat atagaaattc aaaagagtaa
    17881 tatactttta ttaggaccta caggttctgg aaagacatta cttgctcaaa ctctagcaag
    17941 aactctaaat gtaccttttg caatggcaga tgctacatca ttgactgaag ctggatatgt
    18001 tggagaagac gttgaaaata tacttttaaa acttattcaa gctgctgatt ttgatataga
    18061 aaaagctgaa agaggtataa tatatataga tgagatagat aagattgcaa gaaaatctga
    18121 aaacccatct ataactagag atgttagtgg tgaaggtgtt caacaagcac ttctaaaaat
    18181 attagaaggt actgttgcaa atgttccacc acaaggagga agaaaacatc cccatcaaga
    18241 atttttaaag atagatacta ctaatgtatt atttatatta ggtggagctt ttgatggatt
    18301 agagaagata attcaaaaac gtggtggaga taaaacacta ggttttggag ctaaaataga
    18361 aagtaaaaaa gaattagatt tagggaagct gtatgaaaaa gtacttccag aggatttatt
    18421 aaaatatggt ataataccag agtttatagg aagaatacca gttttagcta ctttagagtt
    18481 gttggatgaa gatgcattaa tgcagatatt acaggaacct aaaaatgctc tagtaaaaca
    18541 gtataaaaag ttattggagt tagatgatgt tgagctagaa tttgaagaag gtgctcttcg
    18601 tgcaatcgct aaaaaggcta tagaaagaaa tacaggagct agaggactta gaagtatagt
    18661 tgaaagcgta atgatggaaa ctatgtttga agtaccatct agagataata taaagaaggt
    18721 tatagtaaca gagaaatctg tgaacgaaga ctcagtaaat cctatcatag tacttaagga
    18781 tcaagaggaa agtgcataag atgatgaaaa ggagctttaa aagctccttt ttttatgtta
    18841 atatgctaaa tataaaatag gtatcattat cataaaaatg tgagtaatat acctagaata
    18901 ccaaagacga atacaattgc aatggaacca atttttcctt tatataaaag ataaaatgat
    18961 gctataaatg caattattcc atataaatcc caattaactt ctttggcaga tgaaaaagct
    19021 gctgataata tgaatcctag agtaattggt ctaagaactg tcaataagtt ttctaccttt
    19081 ttattatttt taaatttaga aaataacttt gatataatag ttagacctat taatgcaaaa
    19141 attgtaacac caatagttgc agctagagaa ccaaagaagc cagcagtctt aaatcctaca
    19201 aatgtagcac tatttattgc tacaggacct ggtgtagatt gtgatatagc aagtaaatcc
    19261 aaaaactctt gattagttat aaagtgatat ttagatataa attcttgctg gataaatggt
    19321 agcatggcat aaccgccacc aaaactaaat gcccctattt taaggaatat taagaagagt
    19381 agtattattt ctgacataga ctatatacac ctcctccaat tattaaataa atagggctta
    19441 tattgaatac accaacagat aaaactgcta taattaatag tagtatgtta gttttagact
    19501 ttggtagttt cttgaacatg ctcgtaaaag aatacaatat aagagctatt acaacaggcg
    19561 caactccttt aaaaaatcca tctaaaattt tagatgatga atttttaaag tatagatacg
    19621 ataagactaa gactatacaa aatgatggta aagcagagcc taaggtacat ataagaactc
    19681 ctggtatacc ataaagttta tatcctaata atacagatat attaactgcc agtactccag
    19741 gataactttg agctatggat aaataatcaa taaattcttc ctgctctaaa agtttttgtt
    19801 tgtttacaag ttcatcttgt ataagaggaa ccatagcgta tccaccacca aatgtaaacg
    19861 caccaatttt taaaaaggtt aaaaacaatt tcaacataat agaaacctcc aaaagataaa
    19921 taacatctaa gtatactaat attaatatta tatcataata aaaagataat atagtatgat
    19981 agtattctaa gaatttatca ttaatgttga aaattaactt gttcaaatat ataatattaa
    20041 aagcaaagca attagactag aaaaggagta atgttgatgg aacaaaatta tactaaaata
    20101 gatcatgaat taccattaat tcctctaaga ggattagcta tatttccata tatgatatta
    20161 aattttgata taggtagaga gatatctctt aaagctttag accaagctat gatggatgaa
    20221 gaacttatat ttttaacttc tcagaaagaa gcagaggtag atgagccagg agaagaggat
    20281 ttttatcatg tgggaacaat ctgtaaagtt aagcaaatga taaaattacc aggagataca
    20341 gttcgtgttt tggttgaagg tgtatcaagg ggtagagtaa agaaaataga acaagaagat
    20401 gggtatttca gagcagtaat agaagaaata gtatttaata gtgataattt ggatagtgaa
    20461 acagaagttg aaattgaagc atttgtaaga aatgtatttg atgcctttga agagtatata
    20521 aatattggaa atagggtatc accagaaata ttaatatctc tagctgatat agaagatgta
    20581 gatagattta tagatacgat agctgcaaac atatatctaa aatcaagcca aaaacaagaa
    20641 atattagaag aatttgatat tagaaaaaga cttgaactta tttattctat attattagag
    20701 gaaatagata tattaaaaat agaaaagaaa ataactttaa gagtaaaaaa acagatgaat
    20761 aaggttcaaa aagaatatta tcttagagaa caattaaaag ctatacagaa agaattaggt
    20821 gaagaagaag atataaattc tgaagcagat gagtatagag aaaagcttaa aaaaataaaa
    20881 gcacctaaga caaccaaaga aaaaatagaa aaagagatag ataaattttc aaaaatatct
    20941 tctatgtctc cagatgtatc tgtaagtaga aactatttag atactatatt ctcattgcca
    21001 tggaataaag agacaaaaga taaattagat ataactaagg caaaagatat attagatgaa
    21061 gaccattatg gattagaaaa agttaaggag agaatactag agtatctagc tataagaact
    21121 cttgctaagt cacttaaagg gcctataata tgtctagttg gtcctccagg aacaggaaag
    21181 acatctatag taaaatcaat cgccagagca ttaaatagaa aatttgtaag aatatctttg
    21241 ggtggagtta gagatgaagc agaaataaga ggtcatagaa gaacttatgt aggttcaatt
    21301 ccaggaagaa taattaatgg ggtaaaagaa gcccaaacaa aaaatcctgt attcttattt
    21361 gatgagatag ataagatggc agcagattat aaaggtgacc cagcttcagc aatgttagaa
    21421 gtattagacc cagagcaaaa taaggacttt gtggaccatt acttagaaat accttttgat
    21481 ttatcaaaaa tactatttgt tacaacagca aatagtctag gtaatatacc aagaccatta
    21541 ttagatagaa tggaagtaat agaagtatct gggtatatag aagaagaaaa attaaatata
    21601 gcaagaaaat acctacttcc aaaacagatt aaagaacatg ctttaaaaga aaactttata
    21661 aaaatagatg atgaaacttt aagaagtata attaaccatt atacaagaga agctggtgta
    21721 agaacactag aaagaactat tggtaagatt tgtagaaagg ttgccaaaaa atacgttgaa
    21781 gacccaactc ttgaagaggt tgttataaat aagtctgacc tagagacata tcttggaaaa
    21841 gacatgttta agtatcaact tgcagaagtt aatcctcaaa taggattagt aaatggtctt
    21901 gcatggacag cagttggtgg agttacactt gaagtagaag taaacgtact taaaggtaaa
    21961 ggagaaattg tattaactgg aaaattagga gatgttatga aggaatctgc gaagacaggt
    22021 atctcttata taaggtcaat agtggacaag tttgatatag accctgaatt ttataagacg
    22081 aatgatattc atatacacat tccagaaggc gctgttccaa aagatggacc atcagctggt
    22141 ataactatgg ctcttgcagt aatctcagca cttactaaaa gacctgttcc tggaaatata
    22201 gcaatgacag gagagataac tttaagaggt agagtcttag cagtaggagg ggttaaagaa
    22261 aagttattag cagctcatag agctggtata acaaaagtat taattcctaa agaatgtgaa
    22321 gctgatttag atgaaatacc agaaaatgta aaagaaaaaa tggagtttgt gcttgtagaa
    22381 catatggatg aagtattaga acaagcttta ttaaagagtg gtgaaaataa tgaaaattag
    22441 aagttcagag ataactatga gtgctgtgaa taaatcacag tatccagcag aaggaatccc
    22501 agagatagca ttggctggta ggtcaaatgt tggaaaatca tcaataataa atacattgct
    22561 taacagaaga aacttcgcta gaaccagtca aacaccagga aaaactagaa ctataaattt
    22621 ttatctaata aataatgaat tttattttgt agaccttcca ggctatggat atgcaaagat
    22681 agctaagtct gaaaaagaaa agtggggagg tataatggaa agatatctag aaagtagaca
    22741 agagttatgt tctatattcc tacttgtaga tattagacat gagcctacag cagatgataa
    22801 gcttatgtat gaatggataa agcactttgg atataactgt gtagttattg caactaaggc
    22861 agataaaata tctagaggac aatatcaaaa acacataagt ataataagaa aaaaattgca
    22921 aatggaaagt agtgaaaaag taattcctgt ttcttcacta aaaaagactg gtgttgaaga
    22981 attatgggaa gagattgtaa atcaatacaa tcaacatgga tatgaaataa cagtagatta
    23041 aatttaaaat gttaaatatt gacataagat ttatttgaat aataaatgta ataatagtta
    23101 gttttaatta tattaatatt aaagcaaaat ataggatgcc ttaaaatagt tttaatgaac
    23161 tttttttggc atccttattg tttataaaca ataaatatca gtaattttgc taaatactaa
    23221 taaattttag taaggtatgg gaaaattagt ataaattagt tcaactaaaa aattattgac
    23281 ttatgtagtc agcaataaat agcatttaag aaatagattt atctgttttt ctcataaaga
    23341 aaacagttag tataagccct ataaaacata ctgatgctgc aatccaataa gactgattgc
    23401 tagctataac ataggctgat gtgtgacttt taaacttttg attgtatgta agactttgtg
    23461 caaaaaaact actaaaaaat gctgttccaa gagcaaatga taaattacga atagttgcaa
    23521 gaaaactgcc tccgtacccc tgtttttgag gaggaacatc tgctaaaata ctactattgt
    23581 ttggtgaact aaatgctcct agcccaagtc caaaaataac taaacataca attaaaagat
    23641 acaatggaga atctgctttt aaaagtgcca ttccaactag tgagatggtc ataaatgaaa
    23701 aagatgctgt tagaatgttt tttgcaccgt gtttatcaga aagtgaacct gcaataggtg
    23761 ctataagtac cataataagt ggatgtacag tcattacata accagccatc ataggagata
    23821 aattttttaa ttgttctaaa taaaatggaa gtagaaaaga tactgccatt tgaggaaaat
    23881 aacaagctac tccaatgata ttgcctacag taaagtttct atttttaaat agaggtaggt
    23941 caataaagct ttgttcaaat tttacttctc ttaatgccaa caataagaag attataagtg
    24001 ctgttatacc taaatacaat cttgtattac ccttctcatt cattgcaagt aatataagcg
    24061 tagtgcaaga tgcgaaaagt agaagacctg aaatatcaaa gctcttgttt tgttcatcca
    24121 aaacaggttt aggcagaaat ttaatgccaa gaaagactgc tataatacca ataggtatat
    24181 tgataataaa aatagaaggc catccaaaat gttctaaaat tatacctcca attacaggac
    24241 cactcatatt tcctatacca actacagctc cagtgattcc tatagctttt cctttttcat
    24301 ttgctggaaa tgcattggaa actataccaa gcccagtagc cattaaaata cttgctccaa
    24361 ctgcctgaaa gattcttgaa gaaattaatg ttgataaatt gtttgacata ctacacagaa
    24421 aagaacctat tgtaaatata aaaaatccta atgcgtatag acgatttgaa cctactttat
    24481 caccaagttt tccgaaaaat aacatagtag ctgttacaac aagcatataa gctgttacaa
    24541 cccactgaat ttgtgacatg ttaattttaa agtcagcagc aattgtagga tttgcgatat
    24601 ttagtatact tccatcaaga gtagacataa atacaccaat acagatgata atcaatacta
    24661 tccatttttg tttcatgata acactccaat cttaatagat tttataagta cgatataatt
    24721 gtaaaataaa caacaaaaaa agcacctgta tattaggtac cttgaatgtg tctaatttca
    24781 tgaataaata cggtagttga aggatttgta tagattactc atgtaaaatt acataaaggt
    24841 actcatatac tattttcttc taccatccag attttactgt cggctttgga atatgaccaa
    24901 attatgccat aaggctcgcg ggcttttacc gccgataggg aatttcaccc gtttatgaag
    24961 aaaaacagat gtattttgta atattatttt aacataaaat tataatggaa acaattggat
    25021 ttaagtaata tccagctgta ttacaataca aatatttcaa tatggacact taaattgtat
    25081 ttatagatag aataaggtac agtatgagaa tctataataa ttagataaaa ttaatatgtt
    25141 attagtatta gatggtaagt tttaaatttg tcaaaatcag aaagctgtaa taaaattctt
    25201 ataatatgaa tatcttaatt aagagatatt gtaaattatg aggaggcgct aatatggaag
    25261 gaaaggtaaa gaaggcattc ccaggtggaa atacatcaca aggctcatat tctttttttg
    25321 actatataat tcctgaaaat gtaaaaagag ttttttgttt aaagggtgga cctggagtag
    25381 gaaaatcctc acttatgaaa aaaatttata aagagttttt gcatagagga tatgatattg
    25441 atttatatca ttgtccttct gacccaagtt cgttggatgg tttagttata aagaaattag
    25501 gcgtggtact tatggatgca actgccccac atactatgga cccaaagcta cctggagctt
    25561 tggatgagat aattaattta ggtgattact ggaatacaga agaattagaa aagaataaac
    25621 aagaaatatc agtttatgat aaagatatta gtaattcatt taaaagagca tttaagtttt
    25681 taaagtcagc agaaccaatt tttagagaca tagaagaaaa atattctgat tgtatggatt
    25741 atggcaaagt aaatttggtc acagaagaat ttataaaaag gttatttgat ggagttaaaa
    25801 gcacaggaaa tctaaaaaga gaaaagcatt tatttggttc agctataact cctgtagggt
    25861 gtttagatta tacagaaaac attttaaaag atgtaaagaa agtctattat ttagatggag
    25921 aaataggaac tgggaaaact acattattaa acaaagtata taagaaagct actgaaaaag
    25981 gtttaaatgt agaagtttat cattatccac ttattccaga gaaaattgaa actgtactat
    26041 taactgattt agatataggc ataactataa gtacgacttt taaagaagaa gatacaattg
    26101 atttaaatca gtttttaaat agagaaaaac tacttaaata tgaagaagat attaaatttg
    26161 atgaaaaagt tttagatgat ttaatttgtt gggcagtact aaatcttaag agagccaagt
    26221 ctaaacatga tattatagaa agttactata gtcctaatat gagatttgat gaagtaggga
    26281 aattaagaga taagttaatt aaaagaattt taaaatatga ggaaaactta taaacgtata
    26341 tgtttaaaat taatgttaat aataatataa tttttagtaa attggtgtag ctttgaggct
    26401 atgccatttt actttttttt gctaaaaaat gatattaata atctccaaag ccattatttg
    26461 tttttcataa ttattatttc ctttcctaat ttatgttttt ttataatatc acaacaatgt
    26521 ttattgaaag tttatataat tttaagaaca tctaaaaatg catacttgat attggtaaat
    26581 tagtgatagg agttcaatgt atgatattat atactaaaga tgaattttaa tatataactt
    26641 tgatataata agcatatgta aatgtttaat atttaattaa agaaaattat catataaaaa
    26701 taaatttgta aggagcaata cagtatgaaa aaacaatatg tgtttataat actagcaagt
    26761 actattttag gtatacttgt tggaaccata tttagagatt atagcaatga agaaacagtt
    26821 tatacaagca aagacaagtc aataagaaaa gaaataaaaa tgacaagaaa atctataaaa
    26881 gaattaacca aagagaaaga caagttagat aaagaaatta attcaatgaa acaaaatcaa
    26941 aaaaattctg aagaaatatc agaaatagaa acacttagag atagtctatc atattcagat
    27001 gtaaagggta gtgggataat attaagtata gatgctatag atgaaaaaac agggaatata
    27061 gctaatagta tagactataa taagattctt gtaaaagtta taaatgaatt aaaagtaaac
    27121 ggaggaaaat acatagaaat aaatggtcaa agaattaatc aatattcaga agttgtactt
    27181 gcaggaagcc atataaatat aaatggagtt cctgtagcac aaccatatga aataaagtgc
    27241 attggagata aggagaaatt atctaattat gtagataaag gtagtaaata tttagatagc
    27301 atacaaacca attatccaat gaaaataagc ataaaaactg aagaaaatat ctctatgaaa
    27361 aaaatgaata tacctaataa attaaagtat ataaagggtg attaatatta tattagagga
    27421 aagcagtttg ccaatgttaa taccagaaaa acttgcaaag aaatataatg tatttccagt
    27481 tgagtttcaa gatgataatt tagttgtaga aatagaagat gaggatattt atgctctaca
    27541 ggacttgaga ttagctacag gtaaagaaat tatattgaag aaggagaaaa aagaacttat
    27601 aagtgaaaag attgaaaaat attataatag ctttgaactt gatgaggatt atgcaaaaaa
    27661 attatttgaa aatcttttag aaaaagctat aaaagaaaat gcaagtgata tacatataga
    27721 accatttaaa gaacatttaa tagtgagaat gagggtagat ggagaactaa aggaagtatc
    27781 aaagttttta gttgatgtct atccatcatt gtctacggtt ataaaattaa aggcatcaat
    27841 ggatataaca gaaaaaaggc ttcctcagga tggtagggtg gatataaagt taggtggaaa
    27901 tttaattgac attagagttt catcaatacc aactgtctat ggtgaaaaaa tagttttgag
    27961 gatacttaat agagatactt ttttaaaaga caaattagaa cttggttttt cagaggaagc
    28021 tataaaatct ataaatcgta taataaataa aagagcagga gtattattag tgacaggtcc
    28081 tacaggtagt ggaaagacta caacagtata ttccttatta aatgatttaa aaggaataaa
    28141 taaaaatatt atgactatag aaaatcctgt agagtataag atggatggca taagtcagat
    28201 tcaagtaaat tcaaaagtag ggttgagctt tgatgtaggt cttagagcga tattaagaca
    28261 agacccagat ataataatgg tcggagaaat aagagatgca gaaacagcta agatagcagt
    28321 aagagcagct ataacaggtc atttagttat aagtacttta catactaatg atgcagtatc
    28381 ttccatagct agattactag aaatgcaaat accaccatat cttttaaatg cctctcttat
    28441 aggtgttata tctcaaaagt tggttagaaa agtttgtaat cattgtagcc atgagattat
    28501 gataaaagat aattttagtg gagatgtaaa tactaaggta gctgtagggt gtgaaaaatg
    28561 taatgataaa ggatactttg gaagaacagc aatttatgaa atcttagaaa ttaatgatga
    28621 tataaagaca tgtataagaa atatggagga ttctagtact attaaagatg tggcacaaaa
    28681 taatggaatg ataacatttg aagatagctg taaaagacta ataaatgaaa aaataacgac
    28741 attagaagag tgtttagtag taaatgaaat gatttaactg aattgtatag ttaaacttcg
    28801 tttggtcagt tgtctttatt taatctattt taattaagat gtttgagtat aaattatatt
    28861 taagtgaaat aaaattaaat gcattaaatt agaaaatatt aagtttattt aattgtaatt
    28921 aatataattt ggaaggtatt atagtacatg agattatcta aaaatatatt ttataattta
    28981 gaaaagtttt atttagtatt aaatagaatc agtgataaag aaattagagt aatttgcaaa
    29041 gagataggca tattgctgga atctggatgt gaaattacaa aaatatttga aatcattgag
    29101 agtcagtcaa gtaaaaaagt aaagaatttg cttagtatag tatcaaatca tattcaaaaa
    29161 ggtaactcaa tagcagaatc atttcaaata acaggtatat tttctaaatt ctttataagt
    29221 atgataaaag caggagaaac tagtggaaac ttagatataa taatgagtga tttatctaat
    29281 tattatgata aagaatacaa attaaaaatg aaaataataa ctatttcaat atatccaata
    29341 atacttataa tattatctat cttatcaatg ttgtttatat tcgtatttgt aatacctaat
    29401 tttcaggtgg tttttaccaa caatggaatt gaaccacctt taataactag agttttaatg
    29461 ggaatatcta cagtggttac aaataactta gcttatataa tatttagttt tatattgttt
    29521 tcaataggaa gcatttattt ctttataaca aatgataata taaaaaaatt gattaattcg
    29581 ttaaaattca aaataccttt tataaaaaaa attaatcagt tagtagctac aacaagattt
    29641 tcaagggcat tgtccgtttt aattagcagt ggaatacaaa ttgtggaagc tatagacatg
    29701 tcagctagtg ttatagacaa cgaatttatt tatgaaaggt taaagatttc taataattat
    29761 ataaaaaaag gaaatagcat aggtaaatct ttgaatttag caaatgtttt tccaaaatta
    29821 tttatttcaa tggcaaatac aggagaagaa agtgggaaac tagataaaag tctaaatgta
    29881 ataaataaat tttatgaaaa tgaattaaat aacaaaatag agcaaataat gaaatttata
    29941 gaacctatgc taattgtatt tatgggatta attattggca cttttatttt agcaatggtt
    30001 gttcctatgt ttgatgcaat tactaatttt tagagagaaa aataaatttt attagatgaa
    30061 acttttgaaa aggagagaat atttaattga taaatttgat aaataaaaaa cgaaaaggat
    30121 ttacacttgt tgaaatgatt gtagtagtaa ctattttagg cgttatatct agtatagcat
    30181 tagttaagta tagtaaggtt caagaaagtg ccaaattaaa tgcagactat acgaatgctg
    30241 ctaatatagt aactgcagct agcatggcaa ttaatgatga tgaaaagaca atagactctc
    30301 taagtgtaga aacattgaag gaaaagggat acctaaatac tgttccagtt cctcagagta
    30361 catcaggtaa attcgaactt gtcataaatg atagcggaac agatataagc gtaaatataa
    30421 attctaaaca attttatcca aaataatatt ttatattgat tgctgtaagt tttaaaatta
    30481 tttttattta agaaggagat ggctataatt aaaaaaattc taaacttaga aataaatgat
    30541 gattatataa ggcttgtatt tttaagaaaa agtcataaaa aagtttttat agataaatca
    30601 attataaaag agattaactt tgatataaaa aatgatagta attcgattga gaagattaaa
    30661 tatatagaag atgtagttag atttgtaaaa gaggagattg gtaaatcaaa aatattatat
    30721 aaaaatttat actttaacat tcaaattcaa gatatagtca ttagaaatgt tgaagttcta
    30781 aatactaaga aaaaaagaga catattaagc atgattgaat ttgaaataac acaatacatt
    30841 ccaataaaca taaataacta ttcaataaaa tataaagtta taaattctaa aaatgataaa
    30901 ttgaatatac aagtaattct tttcccaaag agtattattc aattaattaa gaacatttca
    30961 gaaaatctaa atatgaatcc aaagactata aatataaatt ttgatatatt acaaaagctt
    31021 ataaacttaa atttaataga gaatttttca gaagaagggg tatttataga atgtaaaaaa
    31081 agtcagttaa ttataaatat aacaaaagat aaaaaaataa gagaaacata cttgctatca
    31141 aaagagggaa aatcatatga gttcataaaa agattattaa gggattttaa gtatgtttat
    31201 tactatggta tagaaaattg ttttattgaa gaatacttta aatatacaga taaatctatt
    31261 gaagtaaatc cattaagatt aaaagataaa gtaaaagtag aaaataattt tgatgcagat
    31321 ttagaagaca ataggataaa ttatataaat agtataggaa tgattattta agtgaaagtg
    31381 gataaaacaa taaattttct taatggattt aaaaaaacta aaccatgtaa taaaatctat
    31441 aaaataataa tagtcttaat tttaacgtgt attttattta aatcatttat gtatgtgaaa
    31501 tctataaatg aacttgaaga ttatataaat caaaataagc tagtggataa atcaaagcac
    31561 actttaccaa caacagataa aactagagag aaattttcta aaataaaact taatgaaata
    31621 aaaaaaatat atgaaacaat tggaataaat agtattacta aaatatcgat agataaaaat
    31681 aagctagaga tggaaggtgt gtgtagtgat ttagatgttt taaacaacct aaggaaaata
    31741 aagtacataa aatattatta catagacagt attgtaagag atggagaata ttatagattt
    31801 agaataaaaa gttagatagg tgattatttt tgagattaaa taatagagaa aaaaatctac
    31861 ttaaaatatt gttaatatta gttattatat tggcaagtga tatagcagta agttatttgg
    31921 aagaaaacct aactagtttg aagaatgaaa agcaaaatat aataaataaa ataaataatc
    31981 aagataatta tcaaataaag gataataagc atatagatga taaatatata gaaagtgttg
    32041 aattaaataa aaatgaagaa ttgaaaaata attttaataa ctcattttta gataaaaaaa
    32101 caaataaaga tatagtgtta ttagtagaaa atgaactgag agatattgtg aatgtagaat
    32161 atattaatca agaaagtagt ttagataatc acaataaaaa acaagttaat ttagaaataa
    32221 aagttaatgg agaacttgca aatgtgttga aacttgaagg tgtaatgaag aagttaagac
    32281 taaataataa acttgaaaag atagaaatta acaaattaaa agtcaataat tttgatgttc
    32341 aaaatattcc aaatgaatat aaacaagaaa aagacaatat tgttgaatgt aaaatgacag
    32401 ttagagtcat ataacaaaaa agaatagata aagtaaaaaa ctattatcaa ttaataaaat
    32461 tttatagagg aattagtttt acgataattc atttctacaa gagggattgt tgatgatttt
    32521 atcgaaatcc taattaaagt taatatattg taccaaaata taagtgaatt taatagaata
    32581 tttacttata ctatagattg attaataaaa aaatggtata ataacaaatt gtactttaat
    32641 ttaataataa gggagtggaa gtcatattgt tagggagaaa tgagctatgc ccttgtggaa
    32701 gtggcaaaaa atacaagaaa tgttgtttaa ataaagatat tgtttcagaa agagcatgca
    32761 gaaaaactga actttcacaa aaacaatata cagatttata ttcaaagtta tatgattatt
    32821 caagacagga taagtttaaa gaagaatgtg aaaaagctaa agaaatgttt tatataatgc
    32881 aaaatgatag tgtaaatgaa aaatttgaaa gattttttaa tacttattta atacaagacc
    32941 acataatgga aaataaaaag gttatgacag ttggttttct tgaagaaaat ggtgcaaacc
    33001 taagtcaatc agaagtatca atattaaaaa gtatgtttga atcatacgta agtatttatg
    33061 aggtaaaaga agtttctgct ggaaaaatag tattaaagga ctgtttaagt ggaaatgaac
    33121 tttgtacaga agatgtaaaa cttctgagaa gttttaaaat cggaagttgt atgatagcta
    33181 gaatagttga tattgaagga actaacatat tgatagatat aactataagt atatcaaatg
    33241 aggttaaaga tataatttta aaggatatta tgaatctatt caatcaatat caagatgtat
    33301 acaaagatat gaagtcgttc ttaatttatc atacacatat actatacaag tatatacaac
    33361 agcttttaga cccaagtata gctgaatatt taaagagaga aagagataaa aacgatacaa
    33421 aagttaattc agaaaatgaa ttagctgaag aagaatgtaa agttttagat actcttaaag
    33481 aaaatgtaga aaaagaaaat atagatgcat gtatagagtt ttggaatgaa tataagaaaa
    33541 atcatgaaaa tataaaagga gctgaaaatg gttgggcagc tgctgttgaa tactatgtta
    33601 aaaaagaagc aggacaacct ataactcaag ttcaaatatc aaagaaatac gatataagct
    33661 ctagtacact aggaaagaga tacaaagatt taaaaatatc ttaattaatt ataaaaagct
    33721 ttaagtcata gataaagaat ctatagtata atatatgtat aatgtttaga aagaggtatt
    33781 aataatgagt cttagtttag gaaatgcaat tgctgtatca acgaacttta taaaatctaa
    33841 cccagctgta cctgtgtaca acggagaaga aatatatgca gttatttatc atatagaaat
    33901 aggatataat aatggtgtat cacctgatac caaacaatat ataataatag actataaaga
    33961 gtttgattta tctatggata aaaaaaatga actaataaat gttgctaaag agtactgtaa
    34021 atctaaaggt attgtagaaa acgaaaacct tgaaataaac cttttagaca atgaagaagc
    34081 agagaacttc ttagaaaagg tgtttaataa catgaaggtt ataagaggtc ttataactaa
    34141 aaaaggataa ataaatggac tatataggaa tagaaaatat aacaccttat gaaaatacat
    34201 atgaatttag tgtatatgaa tatgatgatg aaatcacctt aggtagtgaa aagttatatg
    34261 tgtgtgaatt aagggttgta ttgattaaag ttaattctct gtatgttgaa agattgcata
    34321 aatcagttga agcaatggtc ttagtaaaaa acttgaaaaa ggatttagat aaaacacttg
    34381 ttgtaaacaa aataaagaat tttgtgctag atgagatttg ggtagaaaat ctagtaaaag
    34441 agaatataga agttatattt gtagaaagct aggaataacc ctagcttttt tatattacaa
    34501 tctaagagag gaaaacaata tgttaagagt atctaatgta aaacttggaa ttgataaaga
    34561 tatatcttta ttaaaagatg ttgtacttaa gaagctaaaa ataaaagaaa aaaacttagt
    34621 caaatatagt atatataaag aatctataga tgctagaaaa aaaggaaaaa tggaatttgt
    34681 ttattctgta gatgtagaag tcaaagatga aaataaaata cttaactcaa aaataaaaga
    34741 tgtaacaaaa ataaaggaaa tcagatacat aaatgtacct gtgggtgata aaaaattaaa
    34801 gaataatcct ttggtaattg gtagtggacc agctggttta tttgcaggtc tgcttttagc
    34861 tcaaatgggt tatgaaccaa tcatacttga aagaggtctt gatgtagaca gtagaaccaa
    34921 agatataagt gatttttgga caactagaaa attaaaaaat aattcaaacg ttcaatttgg
    34981 agaaggtgga gcaggaactt tttcggatgg taaacttaca actagaataa aagatatacg
    35041 atgtagaaaa gtattagaag agttagttca gtttggagca ccagatgaaa tattatactc
    35101 acataagcca catgttggaa cagatatatt aaaaaatgta gttaaaaata taagaaatga
    35161 aataataagt ttaggtggtc aagttagatt taattcaaaa gtaacagata tagttgtatc
    35221 aaatgattct atacaatctg taataataaa tgatactgaa aaaatagata cagatacaat
    35281 tatactagct gttggacata gtgcaagaga tacttatgaa atgttgtatt caagaggtat
    35341 aaaaatagtt caaaaacctt ttgcaatagg agctagagtt gaacatccac aagatttaat
    35401 aaataaagca cagtacaagg atttttataa tcatcctagg ttaggagctg cagattatag
    35461 acttatagag catgtttcaa atggaagaac agcatatact ttttgtatgt gtccaggagg
    35521 tagtgtcata gcatctgcat caaatgattt tgaaatagtt acaaatggta tgagtgaaca
    35581 tgcaagagat aaaataaatg caaatagtgc atttttagta aatgtaacgc cagaagattt
    35641 taagagtgat aatccactag caggtgttca tttccagcag aagtatgaaa aattagcttt
    35701 tgaattaggt ggaaaaaatt acaatgcacc agttcagctt gttggagatt ttataaacaa
    35761 taagacttct ttgaatttag gaagtgttga gccatcatat agaccaggat atacacttac
    35821 aaatttaagt gaatgtttgc ctagcttcgt aacagagact atgagagaag cgtttatatc
    35881 tcttgataaa aaattgaatg ggtttgcaat gtatgatgct gttttgacgg gagtagaaac
    35941 taggtcatca tcaccaataa gaatagtaag agatgaaaat actttagaat cagtgagtat
    36001 taagaatcta tatccatgtg gtgaaggcgc tggatatgca ggtggtatag ttacagcagc
    36061 agttgatggt ataaaatgtg cagaaaaaat aatacaaaaa tacaccaata atacaaaaat
    36121 ttaacataaa cttaatgatt ttttaatatt taacatgaat ttaacattat cactcctata
    36181 atttgataaa atacaatagg ttataaaatt tttagataca gtaatctctt tacaaggagg
    36241 aaataatttg aacattataa taagtctaat gggtggatta ggtctgttct tatatggtat
    36301 gaaccttatg ggagaaggtc ttcaaaaatc tgctgggaca aagctaaaaa agataataaa
    36361 actacttact agtaacctat ttatgggagt tttggtaggt acaggagtta cagcagtaat
    36421 acaaagttca agtgctacta ctgtaatggt tgttggtttc gtaaatgcag gaataatgac
    36481 tttaaaacag gcaataggag ttataatggg tgctaatata gggactactg ttacagccca
    36541 attggtatct ttcgacttaa ctggtatggc cccagtagca ttaggtgtag gtattatact
    36601 ttatttattt ggaaataagc ctagaataaa aaatatagcc gaaatactta taggttttgg
    36661 tatattattt acaggtatgg attttatgaa gatggcagtg gagccactaa gagactatca
    36721 aggatttact gacctacttg ttacatttgg tagatatcca ctacttggat tattattggg
    36781 atttgggatt acagcaataa tacaaagttc aagtgcatct atgggtatgt tggttgcact
    36841 ggcagcagaa ggtctagtgc cattatcagc agcactgcca attctttatg gccaaaatat
    36901 tggtacatgt gtaacttcac tgttatcaag tattggtgct aacaaaaatg cacgaagagc
    36961 agctatgatg catctaatct tcaatgtttt aggaacggtg atattcttaa tattcttgaa
    37021 taaaccagta gtaagcatgg ttacaagttg ggatccaagc aatgttgcaa gacaaatagc
    37081 caatacacat acattgttta atataatatc tgtattgata cttttaccat ttacaaatct
    37141 tattataaaa ctagctataa agcttgttcc tgatagagca ggtgatatag atgaagatga
    37201 aactaaaact attaaatata tagatgatag aatgatagaa actccttcta tagctcttgc
    37261 aaatacgata aaagaagcac ttcgtatggg tgagaaggcg aaggaaagcc taaatgcatc
    37321 tatggaagcc ttagtagaac attcaactga aaaaatagct aagacatata gacgagagag
    37381 attaatcaat gatttacaga aagctatttt aaattactta cttaaacttt caaaagcacc
    37441 tttagatgat gattcaagag aagttgtgga tactttgttt aatacagtca atgatataga
    37501 aagaattggt gaccacgcta aaaatatagc tgaattatcg caagttgcaa tagattcaaa
    37561 tatttctttc tcagaagaag gacaatctga acttgatgtt atgtataata gagttgtttc
    37621 agcatatact tatgcattag aatcaatgag aactgataat gttgatttag cttgtaaggt
    37681 tataaaaatt gaagaacaag ttgatataat ggagaaatct tgtagagcta atcacatgta
    37741 tagattgaac aataatctat gtagtataga aaatggagtt atttatttag acgtaataag
    37801 taatttagag agaatatctg accatgctgt caatatagca caacaagtta tagcgaagag
    37861 attaggaaat gattaaaaat aattaattta aaataatata aaatttaaaa tagaggataa
    37921 ataaaagaga aactttaaat gatacgttta gagtttcttt ttttgtaaat ttatttgact
    37981 aaaattttta aatttataca tagttatagt atttagaaga atcgatttcc tgataataaa
    38041 tgatgagata tgtatgattt tgtggcaaac ttttaaaaaa aacacctata ttttgtgtta
    38101 taatctcttt aaaacgaata tgctgaaaag agggatttaa atgggaaaaa taaattttga
    38161 ttatagtaaa gctacagagt ttttttgtca aaacgaaata gatgtcatgc aaccatatgt
    38221 agatgttgcg cacgacatgt tacataataa aactggttta ggaaatactt ttttaggatg
    38281 gatagacctt cctaaaaatt atgataaaga agagtttgac agaataaaaa aatctgctga
    38341 gaagataaaa tcagactcag atgttcttct ggtaataggt ataggaggct cttatttagg
    38401 ttcgagagct gctatagata tggtaagtca ttcttttagg aatggactta aaaaagagca
    38461 aagaaaggct ccagaagtat attttgtagg gcataatata agctcaacat atattatgga
    38521 tttattagat ataattgaag gaaaggatat ttctgtaaat gtaatatcta aatcaggaac
    38581 tactacagaa ccagctctgg cttttagaat atttaaagat tacttagaga aaaagtatgg
    38641 taaggaagaa gcaagaaaga gaatttatgc aacaacagat gcaagtaaag gtgcacttag
    38701 acagttagct acagaagaag gatatgagac ttttgtaata ccagatgatg taggtggtcg
    38761 tttttctgta ttgacagcag ttgggttact tcctattgct gctgctggac ttgatattga
    38821 tgctatgatg aaaggcgcaa atgatgctag agaagcattt caaaatcctg acttaaaaag
    38881 taatgatagt tatagatatg ctgttgctag aacaatttta catagaaaag gaaaagatgt
    38941 agagttatta gtgaactatg aacctcaact acattatgta agtgagtggt ggaaacagct
    39001 ttatggagaa agtgaaggaa aagaaaataa aggtttattc cctgcttctg tagatttctc
    39061 aacagattta cattctatgg gtcaatacat acaagatgga aaaaggcttt tatttgagac
    39121 agtacttaat gttgaaaact gtaagagaaa tataactata agttcagagg aagtagactt
    39181 agatggttta aattatttag caggtaagac tgtagatttt gtaaatcata aagcttttga
    39241 aggaactcta ttggctcata cagatggaaa agtacctaat ttagtaataa atatacctca
    39301 actagatgag tataattttg gatatttagt ttatttcttt gagaaggctt gtggaataag
    39361 tggatattta ttgggagtta atccatttga ccaaccagga gtagaagctt acaagaaaaa
    39421 tatgtttgct ttactaggca aaccaggtta tgaaaaagaa aaggaagagc tagaaaaaag
    39481 acttaaataa ttttaaatag ttaaggttta attaagatta aaataatata atgaaatcat
    39541 cgaaaaggag tttactcaaa atagatgatt tcattttttt tatgaaaaat tgggaaaaat
    39601 atattttgat aatttatatt atattaagat agggagtggt atgagatgtc aagaagaaag
    39661 aaagggataa gtttagtaat attagttgct ataataagtt caatacttag tagttttcta
    39721 acaataattt tagttaagga caatttagta agcaaatcta caggaagttc tacgccgata
    39781 gttgtaaatg atgatggtaa gagtcaaaat atttatcaag cagttgcaga aaaagctacg
    39841 ccatctgttg taggtattac aacaactagt gttgatacta gtaatatgtt tgcaatacca
    39901 actgaaacac aaggtgtagg aactggaatc atagttgatt caaatggata tatacttact
    39961 aattctcatg ttatatcaga tggtcaagct acaagtgtaa atgtattatt caatgatggt
    40021 tcaacaactt caggtaaagt agtatggttt gaccaacaac ttgatttagc tatagttaag
    40081 gttgataaaa ctggactaac accagcagaa tttgctgata gtgacaaagt aaaagttgga
    40141 gatatatcaa tagcaatagg taatcctctt ggattagatt ttcaaaaaac agttactcaa
    40201 gggataataa gtggattaga tagaactata caaacagaaa aaactaatat gactggttta
    40261 ttacaaactg atgcaagtat aaatgcagga aatagtggag gaccattgtt aaatcaaaaa
    40321 ggtcaagtaa ttggtataaa cacagcaaaa gcttctcaag cagaaggatt aggatttgca
    40381 ataccaatca atacagctaa gagtatagtt gaagaagtaa tcaaaaatgg aaaatatgaa
    40441 aaagtaactt taggcataaa aggtacagat gtatcaaatt atgaagcagc aacaggtaca
    40501 aaattaagta ctgataaagg tgtttatgtt gcagaagtaa tatctggttc atcagcagaa
    40561 aaagctggag taaaggtagg ggatattata actaaagtag gagatacaga tataacaggt
    40621 atgaatgatt taaataaaaa gttgtatact ttctcaaaag gtgctagtac aaaaataaca
    40681 gtaaatagag gcggaaaagc agtaacaata aatgtgaatt tctaaatatg accagaaaga
    40741 aggagactac atggtaaagt gtagtctcta tttttattta atttttatag tatatacatc
    40801 taaattaatt aaaatgatgt attgtttata gtttattgct atattttctt ataaaaataa
    40861 atttaataaa tatttaaatt taatttacaa aaacaatata aatatcataa taaaataaaa
    40921 ttttttaata ttactaaaaa tatatagaca aaataataac aaatatagta ttatgtaatt
    40981 gtagaaatgc ttttcatagg tatattctat gaagatgaat tgcataaaaa tgaaaaaatg
    41041 gaatggatat tatttagggg tgaaaaatca tgaatccatt agttataaac ttacaaaaat
    41101 gtagcataca tgatggacca gggataagaa gtacagtatt ttttaaaggg tgtccacttg
    41161 aatgtgtttg gtgtcataat ccagagagtc aaacatatac aaaacaagtt ttgtataatg
    41221 aagaaagatg ttcaaaatgt gaagcatgta taaatatatg ccctcataag gcaatttaca
    41281 aaggtgaaac aaaaatatgc ttagaccaag ataagtgtga gttttgtgaa acttgcttag
    41341 actattgtgt aaacaatgca agagagattg ttggtcaaga gtattctgta agagacttgg
    41401 ttaaagagat agagaaggat agaattttct atgaagaatc gggtggtgga gtaacactat
    41461 caggtggaga agtaatggct caagatatgg acttcatttg tggagtaata aacatgtgca
    41521 aatcaaaggg aatccatgta gcaattgata catgtggcta tgcaaagtca gaaaattatg
    41581 aaagagttgc taaatgtgca gatttgtttt tatatgatat taagcttatt gatgaggata
    41641 agcacataaa atttacagga aaatcaaatg acttaatact gaaaaatgtt aagattttaa
    41701 gtgaattagg ggttaacata aatataagaa taccattaat tgtaggagta aatgtagatg
    41761 atgaaaattt agaggttaaa aaaatgatag agtttttaaa gcctttgaat atacaagcag
    41821 taagtcttct tccatatcat aatattggta aacacaagta tgataaaatt tataaaaagt
    41881 atgaaggaga agaactacaa agaccatcag aagaaaaatt agaggaaata aaaagactgt
    41941 ttgaagcaag taatttcaat actaagattg gagggtaata aaatggcaag aggaactttt
    42001 gagagaacta aaaaattaag agaagaaagt attaatgcag aaccacacat atctattgaa
    42061 agagcagtac ttatgacaga agcttataaa aaatatgagg gaagtgtaga gattcctgta
    42121 cttcgtgctt tatcatttaa gcattatatt gagaatagaa ctcttagcat aaatgatgga
    42181 gaattaatag taggtgaaaa aggtgattct cctaatggag caccaacata tccagaaatt
    42241 tgttgtcaca caatggaaga tttagaagta atgcacaata gagatataat aaattttagc
    42301 gtatcagaag aagctagaaa aatacataaa gaagaaataa ttcctttttg gaaaaaaaga
    42361 caaacaagag ataagataat aaatgcaatg acacctgagt ggttagcagc atatgaagca
    42421 ggtatgttta cagagtttat ggaacaaaga gccccaggac atacagtttg tggagataca
    42481 atatataaaa aaggattttt agatttaaag aaagacatag aagcaagatt aaaagagcta
    42541 gattttctta atgatttaga tgcatataat aaaaaagcag atttagaagc tatggcaata
    42601 gcttgtgatg caatggttat attaggtaaa agatatgctg agaaagcaag acaaatggca
    42661 gaagaagaaa cagatgaagc taagaaaaaa gatttattac taattgctga aacttgtgat
    42721 gttgtaccag ctcacaaacc agaaacttat catcaagcta tacaaatgta ttggtttgtt
    42781 catatagggg ttactactga acttaatata tgggatgctt ttactccagg aagacttgac
    42841 caacatctaa atcctttcta tgaaagagat gtagaaaatg gaatactaga tagagataga
    42901 gcacaagaat tacttgaatg tttatgggtt aaatttaaca atcagccagc accaccaaaa
    42961 gttggtataa cattaaaaga aagtagcaca tatacagatt ttgcaaatat aaacactggt
    43021 ggaataaatc cagatggtca agatggtgtt aatgaagtta gttatataat acttgatgtt
    43081 atggatgaaa tgaaattgat acaacctagt tcaaatgttc aaataagtaa aaagactcct
    43141 caaaaattct taaagagagc ttgtgaaata tcaagaaaag gatggggtca accagcattt
    43201 tataatactg aagcaatagt tcaagagctt atggaagctg gaaaaactat agaagatgca
    43261 agacttggtg gaaccagtgg ttgtgttgaa actggatgtt ttggtaaaga agcatatgtt
    43321 ctaactggat atatgaacat tccaaaaata cttgaattaa cattaaataa tggatatgac
    43381 ccaattagta aaaaacaaat aggtattgaa actggagacc ctagaaattt ccaatcttat
    43441 gaggaactat ttgaagcatt taaaaagcaa ttacattata tgattgacat aaaaatagaa
    43501 ggaaatgctg tgatagaaaa tatatgtgca aaacacatgc cttgtccact tatgtctaca
    43561 atagttgatg attgtataga aaaaggcaag gattaccaaa gaggtggagc aagatacaac
    43621 actagatata tacaaggtgt tggtatagga actataacag atagtttaac agcaataaaa
    43681 tataatgtat ttgataagaa aaaattcgat atggatacat tgcttaaagc acttgatgct
    43741 aattttgaag gatatgaagc tatacttaat ttagtttcaa ataagactcc taaatatgga
    43801 aatgatgatg attatgctga tgaaataatg caagagatat tcaatgcata ttacaatgag
    43861 gtaactggta gactaactgt ttgtggtgga gaatacagag tagatatgtt accaacaact
    43921 tgtcatatat actttggaga aattatggga gcaagtccaa atggtagact ttgtgcaaaa
    43981 ccagtttcag agggaatttc acctgaaaaa ggtggagata ctaatggacc tacagcagtt
    44041 ataaaatctt gtgctaagat ggaccacata aaaactggtg gaacattatt aaatcaaaga
    44101 tttgcaccat cagtagttca aggagaaaaa gggttagata atatggctaa tctagtaaga
    44161 gcatacttta atatggatgg tcatcatata caatttaatg tatttgataa aaatgtactg
    44221 ttagaggctc aaaagaatcc taaggattat aaagacttaa tagttagagt tgcaggatat
    44281 agtgaccatt tcaataattt aagtagaaca ctacaagatg agataatagg aagaactgag
    44341 caaacattct aggtttgctt gtaaataaaa cttcttacta tataaaatcg taactgatat
    44401 aataaagtat aaatggtttg attccatttt taaaatttta gattaattat gagctaactt
    44461 tctaaatagg aagttagctc gttaagttta atgaaaaaat cgttaaattt atatttagta
    44521 aatcatacac atattagtaa gtaatacata caaaagaata atttattata gttataataa
    44581 ggttatattt tataaaaata agataatttt aagcagttaa aataaagtca atttagctac
    44641 tttaaaataa aactaataga aaaaaggaga tttgatatga aaactttagg atttattggt
    44701 tcagggaata tgggaagtgc aatgataggt ggcatagtac agtcaggatt agtaaaggca
    44761 gaagatataa ctgtatcaga tttaagccaa gttgccttag ataaagtaaa agaagaattt
    44821 ggaataaata ctacaactga ttcaaaggta gctgttacaa attctgatgt ggtaatagta
    44881 gcacttaaac ctaatatatg cgaaaaggct ttaactccac ttaaagaatt aatagatgca
    44941 aataaaataa tagtatctat agcagcaggt aaaactatag aaagtctgga aagttttata
    45001 ggttcagata aaaaaatagt aagagtaatg cctaatactc cagcccttgt tggcgaggga
    45061 atgtcagctc tttgtaaaaa tagtaatgta acagatgaag agttaaatat gattaaggct
    45121 ctgtttgaat cttttggtga ggcagaaata gtatcagaat atttaatgga tacagttaca
    45181 ggtattagtg gttcttctcc tgcatatgta tttatgttta tagaagctat ggcagatgca
    45241 gcagtattag ctggaatgcc aagacaacaa gcttataaat ttgcatctca agcagtaatg
    45301 gggtcagcta agatggttct tgaaactgga aaacatccag gtgaattaaa agatatggtt
    45361 tgttctccag caggaactac tatagaagct gttaaggtat tagaagaaga aggctttaga
    45421 gcagcagtta taaaatctat tgttgcttgt atagataagt ctaaagatat gagcaaataa
    45481 cagatgtaat taagtttact atatggtttc ttgaattgtt tttttagtac ttatttatat
    45541 ctatacataa atgtatttgg tataagtaaa ataagagtaa tttactataa aaaggaattt
    45601 aatgattgag tgagaattta ttacttaaat attaataatt aaatagatat atttttaact
    45661 atatttgaga tatatcattg tgaaaaaata aaatttataa gtattattgt gaggttataa
    45721 gtagatttat ttaaaaataa atttatttat agccttttta aatttgaaat aatattcata
    45781 aggtaataaa agttacaaat attttcttcg ctaataagtt ttaaaatacc tataatgttt
    45841 tactttttat tataataaat acaataaata tattcttata taaattctat gtcagatata
    45901 tggaaagata agaaccttga gattatgtta aaaaatctag attttatact tataaaaagt
    45961 ttgattttac aaccttacaa aagagaatca agataggaat ataattatct ttttcataaa
    46021 tatataaatg atatactaat attatagtat tattgatatt tgtattggag gttgaacatg
    46081 agggatgaaa ttttaagttt tgtaaatgaa tgtgtattat ttaacaactt tgatgaactt
    46141 aaaaaagaaa gtggcataat aacagaagat atagtaaaaa agtttaattt aagtagaact
    46201 caatcaagta gattattaaa tgatttagta aaatctgata atcttataaa gataaacagt
    46261 agacctgtta tttttttacc taaaaataaa ataaatgatg tagtaggacc tacaaaaaaa
    46321 agtatttatg aaaatttaga tgaacttaaa aatgagtgta aattattaaa gcaagagact
    46381 gtgtttaata gtatcatagg atatgataat agcttaaaag aagtaatcga acaaataaaa
    46441 accgctgtac tttatccaaa tggcggactt acaataatgc tgacaggtga aagtggagta
    46501 ggaaaaactt ttttagccaa gataatatac aaatatagtg taagcagtaa tgtattagaa
    46561 aaaaattctc catacaatgt gttaaactgt gcgcagtatt ataataattt ggagttattg
    46621 tctagtctat tatttgggca tgtaaaagga gcatatactg gagcaaatga atctagagca
    46681 ggtctaatag aacaatcaga tggtggtgtt ttatttttag atgaagtaca tagattaaat
    46741 agtgaaggtc aggaaaagtt atttacattt atggatacag gtacgttttc taggattgga
    46801 gagaatggag taattagaaa agctagggta agattaatat ttgcaacaac agaaagtcta
    46861 tccaaatttt tgcaaacttt tttaagaaga atacccataa atatttatgt tcccaatata
    46921 gaagaaagag ggactattga aaaaagaaag attgtagaac attttattta tgaagaaagt
    46981 aaggtacttg gcttgcctat agagataact caaattacat taaatacgat tttaaagata
    47041 aaattcaagg ggaatatagg tgaatgtaaa aatgtaataa aatatgcatg tggacgagct
    47101 tatgcaaaaa atcaaagaag aaatggaaat atttttgtta ctcttcaaga cctccctaga
    47161 aatctttata tagaaaatgt agatatattt caattccaaa gtggtaaaag caaaagcatt
    47221 atcttttctc ctaaacaatt tagtattgaa atgtcaaatg gaagaaataa aagaaatata
    47281 atctatcaaa gtttcataaa atgtttagac tactttgata gactagaaaa aaatgaaata
    47341 acaaaagaaa tatttagtaa aaagagttct aatctaatga ttagactaat ggacaattta
    47401 gtcttttcaa ataatgatga aaataataac gtacttatgg agcttataat atcgataatg
    47461 caggatatat ttagaaattt agaagttaat aacaatataa aatacgatgg gaataatgta
    47521 ttggcatttt cgtcttatct ttatttgaag gacgaatctt atcaattatc tgatgagtat
    47581 aaagctttag aaagtaaatt actaatatat ttaaaaaaag agagttacaa agaatactct
    47641 ataataagta aaatatcaac attaataacg aatagattgg atatgtatct taataatgta
    47701 gatacaatca taatgattat atttattaaa tcaacaatta taagaatgaa atttaatcaa
    47761 gttaatgcga ctattatagc acatggatat gctactgcca gtagtatggc gaatgtatgt
    47821 aatcggatgt tgggtaaaaa tatatttaca gctattgata tgcctataga tgctaccatt
    47881 gctgatgtat caaaacaaat gtctagatac ctagaaggag ataggataaa gaatggttta
    47941 attgtgttat ttgatatggg ctctcttaat cttatctatg aagatttaaa aaataagata
    48001 aatgggccaa tgttatttat agaccaaata tccactattt ctgcactaga agtaggaaat
    48061 ttattaatgc aaggtaaaaa cattgaacag attgcagaaa ttatggatga agaaactaaa
    48121 cctaatatac aattgtatta tcctcaaaaa aataaagaat atgctataat atcatcttgt
    48181 tttacaggga taggtactgc tataaaaatc caacatctac tttccgaaag tttaattggg
    48241 atagttgatg tcaaaataat accttatgat tatgatagtc ttgtttctat gggagataaa
    48301 gaaccagttt ttgaaatgta tgatgtgatg gctatagtag gaactgctaa tccaaatgtg
    48361 aatggggtgg attttatatt gttagaggat ataatatcag gaaaaggaga agatgatgtt
    48421 tttagaatat ttagtagagt agtagaaaat gaaaaaataa agaacataaa tgattctatt
    48481 gtaaagaatt tttcattaat tagagtaata gacagtctaa ctattttaga ttcaaaaaag
    48541 ataatagaga gaatagaaga aggaatcaat gctatagaaa atattcaaaa gaaaaaactt
    48601 ccaaatgata aaaagatttc tttatatgtt catttaagtt gtatgattga aagattagtt
    48661 agacaaactg aaattgaaga gtatactgat atggatttgt taatcaaaaa ccatcatagt
    48721 gaagtaaaac taataaaaaa tgcatttagt gtgctagaaa agagttatag tgtgcaaata
    48781 ccaatttcag agataggata tatttataat attatctatg gtctaccaca gtaaaataca
    48841 agattacaaa ataagtaaat gaaatttaaa atagtatgcc agtatttggc atactttttg
    48901 cttttataga taaatgagag tataaacaat aaaaatttta atgtatgatg gaggatttgg
    48961 ggaaaatggt atctttgatg agaattgatg acagattgat acatggtcag gttgcatatg
    49021 gatgggcaac atcactaggt ataaatgtaa tactagttgc aaatgatgaa gcaaaaaatg
    49081 accaaatgaa agctatgtca ctgaatttag cgaaacctag caatgtaact ttatatataa
    49141 ggggggtaga ggaatctgga gaaatagtag aaaaatttgc ttcttcaaag aaaagcaatg
    49201 tattagtgtt agtaaaaaat accagagatg ctttagttgt agctaaaaat tcaggaggag
    49261 tattaaaaga aataaatgta ggagggttaa gatatgaaga aggaaaaaag aaacttacag
    49321 atttagttgc tgttgatgat gatgatataa ataactttaa agaaataggt gatttaggaa
    49381 ttgatataga acttagaatg ttacctagag acaaaaagaa acaactatca gatttaataa
    49441 aataatttag gagaaagaga atgaaaaaat ttctaattgc aacacatgga gaattgtcta
    49501 gagaacttgt tgacacaagt aaattaataa ttggttcatt agctaatatt gagtattttt
    49561 gtatgacaaa agataaatca gcagatgatg ctgagaaaga aattagaagt atattatcaa
    49621 ataataaaga tagtgaagaa tttgttgttt taacagatgt gtttggtgga agtgtggcaa
    49681 atatatgtac aaacttactt ttgcaagggt tcaaatttga attgttgaca ggcgtaaatt
    49741 taccaatgct tttatctata ttcttattag ttgaggagga tacaaaacta atagttaaat
    49801 caggcttaga ggaagcaaaa aatggaattg tttatgtaaa tgagttatta gaaaatcgaa
    49861 ataaaatcaa aaatgtaatg taatttaatg taaattaaac taagttaaaa tggaggttca
    49921 atatgttagt acaagctact atgttagcta ttatagcagg agttggtata ctagatgggc
    49981 gtatatttgg tcaatctatg tttgataggc caatagttac aggtatgtta gttggattag
    50041 ttttaggaga cataaaatca ggaattatga ttggtgcaca gcttgaatta atttggatgg
    50101 gaattgcagg gataggtgca gctactcctc cagacgtagt aacaggaggt gtattgggta
    50161 cagcttttgc tatattatca ggtaatggtg cagaagttgc tttagcagtg gcagtgccag
    50221 tagcagtatt agcacaatct cttggagtat tagttagaat aataaattcg tacttttctc
    50281 aaaaggcagt tttctatgct aaacaggctg attttaagaa agttaccata atgatgtggt
    50341 tgccagtaat attattcttt ttaagtacat cagttccaac ctttttagca attatgattg
    50401 gtgctgataa agttacaaca ttgataaatg caatacctaa agttatatta gacggattgg
    50461 gtgttgcagg aacattgttg ccagcagtag gttttgcgtt gcttatggat atgttgattt
    50521 caaaaaagat gtctgtattt ttctttatag ggtttttgtt agcatcttat ggtggattag
    50581 atataactgc tatagcttta tttggagtat gtgtagcatt tgtactaaac ttttatatca
    50641 ataacaaaga aaataatcaa aatcctcaat tagcaatgaa tactttaacg gaaggagaga
    50701 ttgactttga ataaattaac aaaaaaagaa ttaagaagta tgttttggcg ttcatttgct
    50761 cttcaaggtg catttaatta cgaaagaatg caaaacttag gttattgtta ttcaatgtta
    50821 cctgcaataa agaagctata taataagaaa gaaaatcaag caaaagcaat agaaaggcat
    50881 ttagagattt ttaatacaac gacagtggta gttcctgcta tattaggtat aacagcagct
    50941 atggaagaag aaaatgctaa taatccagaa tttgatgaaa gttcaattag tgctgttaaa
    51001 acagctctta tgggacctct tgcaggaatt ggtgattcat tattctgggg aacatttagg
    51061 attatagcag caggagtagg agtatcactt gcaaaagaag gcaatatctt tggaccacta
    51121 ttattcttat tattatacaa tataccagca tttgccctta gaatatttgg acttaagtat
    51181 ggttataaag taggggtaaa ttctcttgaa agaatacaaa gagagggact tatggagaag
    51241 ataatgtcta tggctacaac tgtcggttta ttcgttgtag gaggaatggt tgcaactatg
    51301 ttgagtataa ctactccttt gaaatttaac ttaaatggtg cagaagtaat tttacaagat
    51361 atactagata aaataatacc taatatgtta cctttaacct ttgcattttt aatatattac
    51421 atgttgaaga gaaaggtaag tgtaacaaaa ttaactatag gcactatagt aacaggaatc
    51481 gctttacatg ctataggttt gttatagaaa ttaattataa tttattgaat atatagataa
    51541 ggaaggtgta taaaatgaca atacaagatt atatgttaga aacaccagtt agaatgagag
    51601 aaattatatc taatgcagat agcttattta atgaagttaa gagagcaaat ctaaaaaaga
    51661 ttataataac aggttcaggt actagctatc actcaggagt gcaagtgcaa ccatatttac
    51721 aaaatttatt agatatagat gttgtgaaaa tgtatccatt tatgataact gaagatacat
    51781 tcaagtttga taatgaaaat accctagtag taggtgtatc tcaaggtggg agtagttatt
    51841 ctacatacaa cgctatgaag ttagctgaag ataagggttg taaaatagca tctatggcag
    51901 gttgtaagaa tgctttaata gatgagattt ctgattatat attaacagta aattgtggtg
    51961 aagaaaaatc tggagctaaa acaaaaggat attattgtac aaagttaaac ttaatgttat
    52021 taggtcttca aatagctaga gaaaaaggta caatatctag tgaaaagtac aatgaggaaa
    52081 taaataagat attagatgca attaatagat ttgaagcagt gtataagctc tctaaacaat
    52141 ggattgaaag aaacaaagaa aagttagtta attctaaaga aataagaata ataggtcact
    52201 ctgatatata tggagataca ttagaagcag cattaaaatt attggaaaca atgagaatac
    52261 ctgtaactgg gtatgagttt gaagagttta tacacggtat atataatgct ataaatagtg
    52321 attctactat atttatacta gatacaggaa aagaacctag agtaactaag atgattgatg
    52381 tactttctgg ttggacggaa aatgtatttg ctataggtag agatgttaca gaaaatgata
    52441 aaaatttaaa gattgatatc acagataatc cttactatca aacatttaat tttatagtac
    52501 ctatacaact aatatgtggg gaaataccta cattaagagg cgtagaccca agtgttccaa
    52561 aagatactag gttccacatg aagttaggta gcaagaaact gaataagtaa caaaaaaaga
    52621 ggttgtctca aaatagagat aagcctcttt ttgactgttg aaatgatgaa aatatatttg
    52681 attttatata aaaaagagtg cctcatgaac taaaaagtta attttgagac acccactttt
    52741 atcttatttt aaactaaaat atttatatat tagtgtgtat tacttttttt attgctgtct
    52801 tccttacttg agcaagaatt agcacttgga catccagagc aaatagaaca tccactacag
    52861 acatttccgt tttttgtaga cttgaattta ttaaacagaa taaagagtgc aaggactata
    52921 attattccac ctatcaaagc ttccattatt gaattaccca taaatagtac tccacctatg
    52981 cttttaacta taaaagccat tatccatgct agtataaatt gatatgcaaa tgatgtaaac
    53041 atcattttat tgccatattc ttttttcata gttgcaagtg cagctataca tggagtatat
    53101 aaagcagtaa atatcaagaa tgtatatgca gtaactccat taaatattgt tggtaagaca
    53161 acagttagat taccatatag tatatttaaa gagtttacta cgatttcttt tgctccaaga
    53221 ccacttaaaa tagcaactga agttctccaa tcatcaaaac caagaggttt gaatatagga
    53281 gatataatat gacctagagt agccaagaag cttacattta tatcttctgt atatccaaaa
    53341 acattgaatg aagaaagtcc ccaaattacg actgacattg caaacatgac agtaacaact
    53401 cttatcaaga aaccttttga tttattccaa gtatttttaa taagtgcatc tatagtaggg
    53461 attctatatt ctggtaattc taatataaat ggttcagcct ctgttttaaa ggctgtttta
    53521 tttaagaata atgcaactac aattgccata actataccca ccaaatacag tgacgtagtt
    53581 actaaagcag cattatgtgg aaagaatata gctacaaata gtgcatatat aggtagcttt
    53641 gctccacaag tcataagtgg tgcaataaga gctgtaactc ttctatcttt ttcgctttcc
    53701 aatgttctag ttgccattat agctggagaa gaacatccca tacccataac tataggtata
    53761 aaagctttac cagatagacc aacctttctc ataactttat ccattaaaaa tgctgttctt
    53821 gacatgtatc cactatcttc aaacaacgat ataccaaaga ataatgtaaa tattaaaggg
    53881 aagaatggta aagtaccacc aacacctcca attattccat caactataag tgatttaaac
    53941 catgggctag agttagataa catatcacta acaggtgcag aaatataagc ctctataaga
    54001 ctagcaaatc cctcttgtag tggtcctccg acccagtcaa aggtaaattt aaataagagg
    54061 aacaatacac caataaatat cggatatgct aatataggat tcaagactat attgtctatc
    54121 ttatcactga tagatttctt ttgtgtatat gtagtttttg tacatctcga taaaatggat
    54181 tctaattttt tatatgtttc tgtttcactt ccaaagtttt tctgatatat aaaagctttt
    54241 tgcgtagctc ccttaatctc ttcttctatc ctatcaacac catttttctt ttttgctata
    54301 attggaacaa caattactcc aagttcttca cttaattttt tggcatctat attaactcct
    54361 ttagattctg caatgtctaa catattaagc aatataacta taggcttgtt aaattgcata
    54421 agttgagttg ttaagtaaag gtttcttgat aaattagaag catcaactac atttactatt
    54481 acatcaacat cttcattttc taaatatgat ttagaaacct tttcttcatt tgagaaagta
    54541 tccattgcat atataccagg taaatcgaca acctttatct cttttccaag aaatccttct
    54601 tttttttcta tagtaacacc aggccagtta cctacatatt gatttgaacc tgtaagtaga
    54661 ttaaaaacag tagttttacc gacatttggg tttcctaata atgctacatt aatcacgggt
    54721 agctcctcct ctattattgt aaagaaatat ttttagcatc agattttcta atcgcaaggt
    54781 caaagcctct aaatctaatt ataattgggt ctccaagtgg ggcaaccttt ttaacttcta
    54841 tttcagtact atttatacat ccaagtgcaa gcaatctttt agataattta atatctccat
    54901 ctatactatt aataaatcct ttttctccta tttttaaatc gtaaacagtc attattaaca
    54961 cctcctaatg aaattcatta tcattaaaat tgtaacaagt atgatacaaa aagtcaagat
    55021 ttatagaggt aattgcacat tgaaataact aatatttatt ctaaatagat taaaaatatt
    55081 ttagtctaaa ttaggtgttt ttatatattt tgtattataa tgtaagatga tagataaaat
    55141 ttggaggagt taacttaatg aaaactagaa aaatgacatt tttaggtctt atgatagggt
    55201 atagtttagc tttatatgta ctagagacat atataccaaa tcctcttata gttatatttc
    55261 caggggcaaa attgggtttg agcaatatta taactttaat ttcattaatg ttgttaggtg
    55321 tcaaagatac tgttataatt gttactatca gggtaatttt gtcatcaata tttgcaggcc
    55381 ctttatcata tctactattt agtataggag gagcttatct gagtctttta tttatgtatt
    55441 tagcgagtaa aataaaagat ttatcactaa tagggataag cattataggt gcaatagggc
    55501 ataatatagg tcaattaata gttgcaagtt taatcataga aaatatactt gctatagggt
    55561 acttaccatt tatgttaatg gcatcattag taactggtat gtttgtaggc ttagtatcca
    55621 ggtatacaat acctaaatta aagcattttt atagtaagtt ttattgacat aatattgaca
    55681 aaatataata ttgtttgata aaatgtatat aaaaatatac aaatttgtaa tagtggtgat
    55741 tattatggcg aacaatgaat tagaagcgtt aaaaaatgag attgaagcag ttagggaaga
    55801 gataaataca tacatagaat atccagaaat atttcaagaa gagttagtag aatcaagtaa
    55861 gaaaatagat atattaataa ataaatacat gtacctaagc aaatagccca cagttgtggg
    55921 tttttttgta tcaaaaatta acagatggct atattttaca tatattaata ataatattaa
    55981 gatataaaat agtatttctg atgtgtaaat tatctgtagg acataagttg taattaagtc
    56041 aggagggttt tatattatga ttgatatagg aagtaaggag atagcaataa ggttactatt
    56101 agcactaata ataggaggaa taataggctt agagagagaa aaaataagac agtttgcagg
    56161 atttaggaca catatactaa ttgcaatagg ttcttgtatt gtttcaataa cttcgattca
    56221 attattcttt gattataatt tgtatacaaa tgctgaccca gcaagaatgc ctgctcaagt
    56281 attatctgga attggttttt taggtgcagg agcaatttta aaaaataaag gtggagtaaa
    56341 agggcttact acagctgctg ggatgtgggc aactgcatgt attggtatag cagttggata
    56401 tggttattat gaattggcaa ttctaggtgg attatttgta atgatagcat tatttgtgct
    56461 taggataatc aatacgtttt tatttagcca agaaaagaat gtattgatat taaaattaag
    56521 caatttggac tctatacctt ttttatatga taaatttgaa aaaaatcaac ttatcgtaag
    56581 aaatatggaa atagaatgtc gtaatgaaga atactggaag gttaattttt ttgtatctta
    56641 tgctaagaga atacacttac acgacgttat gaaagaaata aatatgatag aaggagtaat
    56701 aaatgtagat tatttggact aaaatatata caatatattt tgtaaagtga ataaaatata
    56761 aaacaaatta aaatagaggt gtatgatatg ggaactgata gaagtacaat agaagaaaag
    56821 tacaaatgga agatagataa gatgtactcc agtaaagagg aaattgaaaa agacataagt
    56881 aaagtaaaaa atcttatcca agaagtaaaa gaatataaag ggaagctttc tgagagtaag
    56941 gagaacttat ataaagtatt aaatatctct gaaaatgcat ctaggattgt tcaaaattta
    57001 tatgtatata ctcatatgaa acaacatgaa gatactagaa ttaatgataa tcaaggaaga
    57061 gccactaaga cagaaatgtt atctactgat ttaggtgtgg ctacttctta tatagttcca
    57121 gaaatactgg cgatagaaga gaataagtta agtgaatact taaaagatga gaagctatcc
    57181 ttttatacaa aatatataaa ggatatattg agagataaac cacatacttt gagtgaacga
    57241 gaggaagaaa tacttgcagc tacatcagaa ttatcgacaa ttccagaaaa tgtatacgat
    57301 atgttagcat atgcagatat ggaatttcct gagatagaag atgaggaggg taataaggtt
    57361 aagctttctc attcaaacta ctctttattt ataaaaagta agaatagtag agttagaaaa
    57421 gacgcttttg aaggtgaatt ttcaacatat gagaaatata aaaatacatt tgcctcaacg
    57481 ctttatggtg gaataaaatc agagatattt tacgcaaaaa ctagaaagta taattcagca
    57541 atagaagcgt ctttattttc agatgatgta agtttagatg tttacaataa tcttatatca
    57601 gctatagata aaagtattcc taatctaaat aaatatgttg agcttaaaaa gaaattttta
    57661 ggattgaatg aaatacacat gtatgatttg tatgttcctt tgacagataa atttgacatg
    57721 gatataccat atgataaagc acaggatatc atattagagg cacttaaacc tttaggagaa
    57781 aaatacttga aggtcataaa aagtgctttt gatgaagggt ggattgatgt atatgataat
    57841 gaaggtaaaa aaggaggagc ttattcttgg ggaagttatg attcacatcc ttatatatta
    57901 atgagctata aaaatgacct taattctcta ttcactttaa ttcatgaatt agggcactct
    57961 gttcacagtc attattcaag aacaagtcaa ccatttttat attcggacta taagatattc
    58021 gttgcagaag ttgcatctac attaaatgaa ttacttctta taaattattt attagaaaat
    58081 tctaagtcta aggatgaaac tatatactta ttaaattatt atttagaaca atttagaact
    58141 acagttcata gacaaactat gtttgctgaa tttgaaaaaa ttgtacatca aagggtagag
    58201 agtggagaac cacttactgc tgatgaattt actaatatat actacaaatt aaatgaaaag
    58261 tattacggaa aatctgcaat agtagataaa caaataggaa tagaatgggc gagaatacct
    58321 catttttatt caaacttcta tgtatataag tatgccacag ggttttctgc tgcaagtgct
    58381 ttaagtcaac agatactttc agaaggaagt actgcagtag atagatatat aaacttctta
    58441 aaaagtggag ggtcagaata cccactagaa caattaaaat ctgctggtgt agatatgact
    58501 aaaaaagaat ctatagagga agccttaaat gtatttgctg aattagttaa taaactagaa
    58561 aaagaattat aggatgtgat aggttgatag cttcaatgaa gacttctgat aatatgagtt
    58621 gtattgtgtt tatatctgcc taaagtaact ttaaaaagtt aatctaatta agaataaatc
    58681 atataaaatt aagtttttac atgtatttaa caatatttac atttacttaa ccctgctcta
    58741 atattcattt aacaaagaat ctgtattatt aaaatataga aaaatgacaa caaaaaatta
    58801 aaatataagc gggggtaagt aaaatgttta aaaagaaaat aggcgttctt ttagctagta
    58861 caatgttagt tggagcttta gcagtaggat gtagttctaa ctcaggaggt tcaggtgatt
    58921 caggagattc aagcaaagtt tctgtttcag gttcaacttc aataggtcct cttatggaaa
    58981 ctatcggaga aaagtttcaa gaaaaaaatc aaggtgttag tgtagaagta caacagattg
    59041 gttcttccgg aggtataaaa aatgccatag aaggaacatc tgaaatagga atgagttcaa
    59101 gagatttaaa agatgaagaa aaaagtgctg gattaaagga aactaaaata gcaatagatg
    59161 gtatagcatt gataactaat actgcaaact cagtaaaaaa cctgacaatg gaccaagtta
    59221 aaggtatata tacaggaaag attactaact ggaaagaagt aggaggaaat gatgcaccaa
    59281 tagtaatagt atcaagagaa gaaggttcag gaactagaga tggattccaa gaaattgtag
    59341 ggtttgattc agaagaacta actaaagatg cacaaataag tgatggttca ggaaatataa
    59401 aaactacagt tgaaggaaat gaaaatgcta taggatatat atcatttgga tatgttgatg
    59461 agaaagtaaa tagtttaaaa ataaatgatg ttgaagcaac tgatgcaaat gtaatggcta
    59521 ataaatatcc aatatcaaga ccatttatat tagttaataa agaagatggt ttgtcagaaa
    59581 aagggaaagc tttaatagat tatatattaa gtgatgaagg acaagcactt gtttcagaaa
    59641 aaggatttat taaagttaat caataacatg aattataata taaagtaaac atataatacc
    59701 ctgtgagata agctcataaa aatgatgctt taacttgcag ggtattgtct attattgaat
    59761 gtagaaatat aaatatcttt agataaaata ggtattttag tatcttatat ctaaaaatat
    59821 ggaaatattg acaaaataat attacaatgt tagaataaaa aagaaattta tgaaaatata
    59881 taaaagattt ttaataaaaa tattttagaa actgagaagt atatcttatt attgggcatc
    59941 tggagatata tggagttagt ggtgcaaccg gctatgaata taatttttat attgcatagt
    60001 ctttttttgc tttaaaatta acaaaaatgt tgcaaaattt gaaaataaga gtattagtcg
    60061 ttaagatttt tattgatagg tgaaattttg gcttttaaag tagccatttg ttggaaaagg
    60121 gaaatttttt aaaaagtata atactattat aataagaaaa taaagttttt ataaacattg
    60181 agatgcaaaa tataaacctt ttgtaacaat atatttacca aaataataca atttatttta
    60241 tattataacc atataaatca tataaatcaa tactcaaact agccaataga caagtttcta
    60301 gaaaaataat aaatttataa gtgaaaatga ctttaagctc cattctccaa caatcggaga
    60361 ctttaattag tatttaataa taaatcttaa tgttcaatac aatattcaag aattgttcaa
    60421 aaatacttaa gtattatagt ctagtttgta aagatattat aaaataataa tactagttat
    60481 atatgaaaat aaaacattat aatttgtaat aattataaaa cttgagatta tgattaaaat
    60541 acctttgaat ggagtggtgt aatgtataat ttactggttg tagatgatga tgttgatatt
    60601 ttaaatataa atcaaattta tttttctaat ataggtttta atgtatatac atcagagact
    60661 gctaaagatg ctatggatat agtagagcgt atagttttag actgtataat tttggatatt
    60721 tcattgccag atatagatgg atataaaatg tgcaatgata taaaagaaaa ggttaacata
    60781 cctataatat ttttatctaa ttatgagcat gaagaagaaa aagttcgggg atttttagct
    60841 gggggggatg attatataac aaaaccttat agtttaaaag aacttgaact tagaatatat
    60901 gctcgtatga ggcagtacaa aaatattaca tcagttccta atgtgttaaa gttttcagcg
    60961 ttagtaataa atgtaaattc aagaaaagta acttttgatg gagaaagtat agatttaact
    61021 actatggaat ttgaaatatt attgtttcta gctgaaaaca aagaacaagt attttcgaag
    61081 atagagatat ataaccaagt ttggaaaatg cctgatattg gagatcaaca tacagtgcag
    61141 gttcatattg cacagatgag aaaaaaaatt aattctttaa gcagggagca tcaatacatt
    61201 caaaccgtat ggggaaaagg atataagttt gtaccataag tgagatactg taattaataa
    61261 atagttcttg ttttatttaa tactactatg aaagagatgt ggttgatgca atgaaaaagt
    61321 ataatatact aaaaggaact ctcattgtat tgatagtctc tctgttggca atagcaggat
    61381 taaatcttct gtataaatat gataataaat atacatataa gtctattaga gcaagtaatg
    61441 gaattttaac tatagataat gatactttca ctaaaggtaa acttgtcttt ctgatagatg
    61501 actgggagtt ttataatcat aaaatattta aaccgaatga ttttacagag caagatataa
    61561 aaccagaata tgtttttata ggtcaatatc cagatttttc tatgagaaaa gggaatcagt
    61621 caccatatgg gaatgctact tatcgtatga gaataaaaaa tgaaggtgag gataagctac
    61681 taagtttaga gcttcctgag attttttccg caagtgaagt atggataaat ggagaaatag
    61741 tttctaaatt aggagatgta ggaacagaaa aatatagacc caaaattaaa aattcagtag
    61801 taagttttat tgcaaagaaa gatacagaaa ttataatcaa tgtatcgaat ttttcacatt
    61861 attatagtgg tttgtattat ccgcctgcat taggagaaac aaaggacata agtaatatga
    61921 tgttttatcg attacttttt tatagtataa tttgcttcac aacttttgca atagctatat
    61981 tttcgttgtc tgtatggttt ctttcaaaca aaagtaaact ttacttatat tttggatgta
    62041 tgtgtgtttt ctttgccatc catgtatcct atccctttgt acatttgtta ggactgcctt
    62101 tggtaagctt tacatatgcg gttgaagatt cgtcctattt tatggtagtt ttatgtatta
    62161 tttgtataaa tggaagtata tccaaaatag aagaagataa agtgtataga tttttaattt
    62221 taccattagg aattacaatg agtatcatat ctatagtgat accaattatt cttcttccat
    62281 atgatatgta ctttgtcaac atatatggga aattaataga catatataaa tatattgtat
    62341 ttatatatat attaatgtct tcgctggttt caatatataa aaagacatgc tctgagcata
    62401 taagttctta tattttagtt tcagtaaaca ctgtttttgg aattagcata ttatttgatg
    62461 cagttactag taatagattt gagcctatat ttacagggtg gcaaacagaa tattgtggat
    62521 ttataattgt tattttattt tctcttatga tgataaacag gaatagaata ataataaaag
    62581 agaatgaaaa acttacaagg aatcttgaac atgaagttga agtgagaact aatgaactta
    62641 caacattgtt aaatgaacgt aaaaaattct tggcagatgt ggcacatgat ttaaaggcac
    62701 ctgtttcagc tatacaatca tttatagact tgataaaggt tggtaatatt catgtagatg
    62761 aagagacaag aacctatctt tatgctataa atcaaaagtc aaatgaagta caaaatagag
    62821 tacgtagttt gcaagaattt acatcacaag ataaaagcat tggtattagt gaaaaaatat
    62881 gtctaaatga ttttattaaa gagatatatg aaaataactt gccagataca caagcatgtg
    62941 gtgtaaactt tgaaacttac atattggaga aaaaaatata tgcaaagata aataaagaga
    63001 tgcttacaag agcatttgag aatttaattt ataatgcttt gacatttact ccatttgatg
    63061 gaaagataat tttatcaatg gataaagaag atggatttgc aattattaaa gtttctgata
    63121 atggaaaagg tatacctcca gaaaatatac caaaggtatt tgacagattc tttacagaaa
    63181 gagataataa tgagccaaaa gggcaagggc tagggttata tattgtcaaa tccattataa
    63241 gagagcatgg cggagaaatc tttgtagatt cagaactagg aaaaggaact gtttttacaa
    63301 taaaattaag tctatgtttt ttataataat agcttattta atataaaaga ataatgatat
    63361 ttgggagtga ttataatgca aactaagata ttgataatag atggagacaa ggataattgc
    63421 cagaagctaa aaggatttct ggaggaaaaa gaaataagta tagatttagc atataattgt
    63481 gaagaagcta ttggaaaaat atttagcaat aaatatgatt taatattttt agaaataatt
    63541 ctaactgatg gtgatggatg gactctttgt aaaaaaatta gaaatgtaac tacttgtcca
    63601 attgtttata tgacttatat aaatgaagaa caaagcattt taaatgcttt aaattctggc
    63661 ggagatgatt acttaataaa gcctctaaat ttagaaatat tatatgcaaa agtaaaagct
    63721 attttaagaa gaatgaactc atatgtaaat aataatgaaa ataatacaaa attagaggaa
    63781 tataatagaa ctagtggagt aataaagtta gaagacaaaa taataaaatt gactccaaca
    63841 gaaaataagc tgttaaactt ttttatagag aatcctgaaa agactctgac tactaaagag
    63901 atatatgaac atgtatggat gaatgagtac ttagaggata actatagtgt ggtagttgca
    63961 gtgaatggat taagaaagaa aatagagaaa gattataaaa atcctcagaa aattataaca
    64021 ataagaggag caggatatta ttttaataaa gaataataaa tatattaatc tcattaataa
    64081 ttgttataaa tgtgaaatgc taacgatatc taaactaaat tattataaaa tagctgactg
    64141 taatttaatt gataaagcct attcttctag actttgccag ttaaattaca gtcagtttta
    64201 ttatatgaaa aaatgcgtaa cagaactatt attttataga ttatatttga aaagatagat
    64261 aaattgtata tctaaatcta tatatattca tttttatctt taatatatgt taaataataa
    64321 aatagttaca taataagatt aagaatttct taataaattc taatgtaaaa aatcatataa
    64381 aaaaattaaa tttagtataa tatatataaa tatatataga aaggatgttt aaagtctatg
    64441 agtggaaaaa ttttagttgt agatgacgaa cgtgatatag ctgatttaat agaagtctac
    64501 cttacaaatg aaaactatat tgtttataaa ttttattctg gtcttgatgc actaaactgc
    64561 attaatttaa atgaatttga ccttgcaatt ttagatgtta tgttgccagg agtaaatgga
    64621 ttttctttat gccaaaaaat ccgagaaaaa tatacttatc caatcattat gttaacagct
    64681 aaggatgaag aaacagacaa gattacaggc ttaactttag gtgcagatga ttatgttact
    64741 aaacctttcc gacctttgga acttgttgct agagtgaagg cacagattag aagatataag
    64801 aaatacagtg gaagtttaca atctggtgaa gaactttcac atattttttc ttttttaggt
    64861 ctggaattga atacccaaac atatgaatgc catttaaatg gtaaagctct ttcacttact
    64921 ccaacagagt tttctattct acatgtatta ttgaaaaata aaggctctgt ggtaaattca
    64981 gaaaatcttt ttcatgctat ctggaaagat gaatattaca ataaaagtaa caatactata
    65041 acagttcata ttcgccatct tcgtgaaaaa ttaggtgata ctgtagatga agcaaaatat
    65101 ataaaaacaa tttggggtgt tggttacaag atttgacacc tatttttctt gtcaagaagg
    65161 gatgtagtat tatgaaaaag attaataatt ttacttatag gaaactaaga gataaatata
    65221 aatttataaa aagagaaaaa aatacagagg cgtatttaaa gtataaatta tatataatgt
    65281 tagctatcta tacaggtata gtattggttt taatgtttat ggctgattat acgttttcaa
    65341 atttttcaaa tcctcttgtt aaatggctta agttgagaag agatgtatta ttttttttgg
    65401 tttttataat tggatatatc actattttca atttttattg gaaaaaacca tggaattatt
    65461 taagagaaat catcaatgca acacatacta tttatcaaca aaatgatgaa ttggttgaac
    65521 tatctaagcc attaaaggaa atagagcaac aaatgaacca aattaagatg tctgttttgt
    65581 taagtcaaca agcagtgaaa gaggctgaaa ataaaaagaa taaccttgtg atgtatctag
    65641 cacatgatat aaggacacca cttacttcag ttattgggta tttgagctta ttaaaagaaa
    65701 tacctaatat ggataattct caaaaatcta agtatactga agttgcactt gacaaagcac
    65761 aatatttaga aaaacttatc aatgaacttt ttgaaataac acgatataat tctaatcaaa
    65821 tcaaaattaa tttcgaaaaa gtagacctat attatatgtt acttcaatta aaggatgaat
    65881 tttacccatt gctgtctgaa aaaggaaata gagccattct aaaagcaaat gaaagtttaa
    65941 caataaaagc agattctgaa aaacttgcaa gagtgtttaa taatatcttg aaaaatgcta
    66001 ttgcttacag ctatcctaat acagaaatta ttatctcagc ggttcataaa gacagcaagg
    66061 tagatattgc ttttagaaat tatggacaga caattccaga agaacaactt tctgctatat
    66121 ttgaaaagtt caatcgttta gatgaagcta gaaaatctga tatgggtggt gcaggtttag
    66181 ggctttctat agctaaggaa attataaatt tgcatggtgg tgatattact gttcaaagta
    66241 aagatgaagt cacaacattt actatatcgc ttcctacatc tatttagtaa aatataaatc
    66301 aaatattagg attttcttaa gaaattatct atttaatatt aaaattatga gtgtctttgt
    66361 ttagtaaaat aaatactaag caagacactt ttgtttttgc aggtaagtag ataaagagag
    66421 gagtttcaaa tatggaatta aaaattgaac atgtgacaaa aaaatttaag gataaaattg
    66481 ctgtagaaga tgtttgcctt accttaacac caggtgtgtg gggatttcta ggagcaaacg
    66541 gagcaggtaa aactaccttg atgagaatta ttacagacat tatgaaacct accaatggca
    66601 aaattctgta taatggaaaa aatatttata taatgggtgc tgagtacaga aatttactgg
    66661 gatttttacc acaagaattt ggtttcccac aggatttttc tgtaaaagat tatttagaat
    66721 atatagcagc attgaaagat gtaccaccaa gagaagtaaa aggaaaaatt aataatctat
    66781 tggaaattct tacattatct gatgtaaaaa ataaaaagat tattaaatta tctggtggaa
    66841 tgaaacgacg agtgggaatt gcacaagcca tgttaaatga ccctaaaatc cttataatgg
    66901 atgaaccaac agcagggctt gaccctggtg agcgagtgag atttcgtaat tttatttcag
    66961 aattttctca taatcgtgtt gtcctaatat ctactcacat tgtatctgat attgagtaca
    67021 tatcaactca aaatgctatt atgaaaagtg gaaaaattct tgatgtggga acaaccgata
    67081 aactggttaa gaaagtagag ggcaaagtat gggaatgtct tatatcaaat agagatattt
    67141 caaaatatga aatgaattta cgtataatca atcagcgtag tgaaaaaaac aatcaagtat
    67201 ctattcgtta cttggcagaa aagtcacaaa ttgataactc tattgctgtt gaaccacgac
    67261 tagaagattt atatttatgg ttatttccag aagcagttta tagtaaggag gggaaataaa
    67321 tgcgtatttt ttatttggaa attaaacgag tgttgcactc acgtcgtaca ttaattttat
    67381 tattgttggc attggtttta tctgcattga tggcttttct tccaattact tacgagggta
    67441 tcaattattt agataataat ggcaaggtag ttgaattgag tggtttagat gctattaaat
    67501 ataaaaaaac aatttatgct aataatagtg aaattagtag tggagttgta acaccaaaaa
    67561 aattaaagca tgctttaaat atatggaaaa aaacagaaga aaagtatggt aaagtaggta
    67621 gtgaagattt cccactagat atttattcta aaagtatttt accaatacgc ccattgttga
    67681 atagacttcc tgaagcattt gctaattcag aaacaggatt tgcaacagaa ttatcagaaa
    67741 taaatacaaa tgatttagat tctttttatg aacaatgcaa aactcattta aatgatatta
    67801 tgaagattga acgacaaact tccagtgcac aaatgaaagc tcaagaactt tatagaaaag
    67861 tagatactcc atttgagata tacccaggtt attctaaaga tgctttcgat tatataatat
    67921 tttacatttt tatattatta attatatgtg ttgcaattac tgcacctact ttttctggtg
    67981 agtatcagac acaatcagat agcatccttc gttgtacgaa acatggacat actcgtctag
    68041 cgtttactaa aatattagct ctattttcta tatttatagt aatgtttgtt gtatgtattt
    68101 ctatccattt ggcaatttct gatttagctt ttggtactga atgtttgaaa acctcatttc
    68161 aaatgttgtt ttctgtcatt agtctagtaa atataaattt actacaagca cagattctta
    68221 tagctattgg tggtctaatt tcaatacttg caatggttag tttaacatta tttttatctg
    68281 caaaatgtaa ggattctctt acttctatgc tgattgcttt ttctatttgc ttaattccta
    68341 tgggaatagg tgttagttgg attggatacc tattaccacc agggggaatt ggtcttaaga
    68401 ttagtttatt atatcaaatg acatcattta atttcttaca cttaggaggt atgagttttt
    68461 ggacaccaca cattatactg tttttctcag tgatagaaat acctattttt atatttttgg
    68521 ctattcgtac ctattgcaaa catcaagtat cataacaatt tgatagaaat aatagtgata
    68581 taaactagag gatacgataa ttatatatgt agtataaaag ttaaatttag ttaacaaatc
    68641 ttaatagcag atataggtaa taaattatac ataaactgta ttattatcta tatctgctat
    68701 tttaatatag agaaacaaca gtatattgta aagtaaatgt caaatatagt tttaaaagta
    68761 aaattaatgt taaaaaagta aatataattt tacacttgct taacttaatc ctaatataga
    68821 tttaacttaa aaaaagtaga ataaaagtac aggaaatttg atgaagacga attataaaaa
    68881 attaaatttt gaatacagaa cgaaaatcga taagtatatt ttaatgggag ggtattatga
    68941 tagtaaaatc tagattagta ggtttagaaa aaaatgacaa taatggcaat aagacaaaat
    69001 acgtaattga aaaagtagca aaaaatattt ttctacttag tgctttagta gcagttgcaa
    69061 gtttactttt gataatagga ttcgtatttt ataaaggctt aagaccattt atatttgaag
    69121 gatattcatt tatagacttt ttaactggtg cagattgggt tccttctgcc aataaatttg
    69181 gaatattatc tatgatagta gcatcaatat ttgcaacact tggagcactt gtgataggag
    69241 tacctgttgg tatattaacc tctgtattta tagcagaagt agcacctaaa agattagcaa
    69301 aaataatgtc accagcagtt gaacttttag caggtatacc ttcagtatta tatggtgtat
    69361 ttggtcttgc agtgatagtt ccaactatac aaagtatatt taatcttcca aaaggtcaaa
    69421 gtttgttagc aatagtaata gtattagcag taatgatgtt accaacaata atatctgtat
    69481 cagaaacagc aataagagca gtaccaaaag catacaaaga aggttcatta gcacttggtg
    69541 catcaaaaat agaaacaata ttcaaagttg tactacctgc tgcgaaatct ggagtattag
    69601 ctgcagtagt attaggagta ggaagagctt taggtgaaac aatggcagta atacttgttg
    69661 caggaaactc accagttatg ccaactgcaa taacagatag tgtaagacca cttacaacta
    69721 atatagcact tgaaatggga tacgcatttg gtacacatca agaaatgtta tttgcaactg
    69781 gagtagtatt gtttacattt atattaattt taaacttagt tttaaataaa ctttcaaata
    69841 aggcggtaaa ttaagatgag aaagttcaaa gagaatctat tgaagtcatt agtatatcta
    69901 tcagcactat ttacaatagt atcattagtc attatagtgg gatttatatt tataaaggga
    69961 attggcaaca tgaattttaa tttcttattt agcaattatt cagcatcagg tgatggtggt
    70021 atacttccaa tgataattac aacattatat acagtagtag tttctatagt tgtagcaact
    70081 cctataggaa tattggctgc tatatattta caagaatatg ctaaaaaagg aaaagcagtt
    70141 acagctataa gatttgcaac tgaaagttta tcagggatac catctatagt atatggatta
    70201 tttggaggaa ttttctttgt agttacatta aaaatgggat attccatagt tgcaggttca
    70261 cttacagttg caataataat attaccagta ataattcgta caacagaaga agctttaaaa
    70321 acagttcctc aagcttatag agaatcatca ttggcattag gagctacaaa atttcaaact
    70381 ttatataagg tagtacttcc aagtgcaata ccaggaatct tatctggagt aatcttatca
    70441 gttggtcgta taattggaga atcagctgca atattactta cagcaggtac tgtagccaag
    70501 atgccaggtg gaatatttga tagtgcaaga acattaactg tacactcata cttactgact
    70561 aaagagagtg gagatatagc aacagcagcc agtataggaa ttgttttaat agtaattgta
    70621 ttagcactaa acatgctagc aagatttgtt gctaagaaat taaataaagc taattattaa
    70681 atttaagagg tgtgaataat ggaattaatc gataagataa aaatgagtgt aaaagatttg
    70741 gatttatttt atggtgataa gcaagcatta aagaaaataa atatggatat aaaagagaat
    70801 aaggttactg ctttaatagg tccatctgga tgcggaaaat caacttttat aagaacgtta
    70861 aatagaatga atgacttaat cgaagatgta acaattaaag gaaacatttc tgttgatgga
    70921 gaggacatat atacctcaga tgatgttata aatcttcgta ctaaagtagg aatggtattt
    70981 caaaaaccaa atccatttcc tatgagtata tatgataatg tggcatatgg tcctcgtaca
    71041 catggactaa gagataagaa gcaattagat aaaattgtag aagaaagctt aaaaggtgca
    71101 gctatttggg atgaggttaa agacaggctt aaatcatctg cactaggact ttctggtggt
    71161 caacaacagc gtatatgtat agcaagagca attgctatga gaccagaagt tattcttatg
    71221 gatgaaccta catctgcttt agacccaatt tcaacattaa aagtagagga acttatagag
    71281 gatttaaaaa aagactacac aatagtcata gttacacata atatgcaaca agctgctcgt
    71341 atatcagatg aaacagcttt tttcttaaat ggagaggtta tagaatttag cgatacaaaa
    71401 actatgttta ccactcctgt agataaaaga acagaagact atataacagg tagatttggt
    71461 taaaatatat aactataaag gagttagaca atggtcaata atagtttaga tataagtatt
    71521 gatactttaa aagaacaaac agtacttatg atggaaaaat gtgaagaagc aatagaaaag
    71581 tctgtgactt gtatgataga gaaggattta gagggtgcaa gaaaagtagt agaagatgat
    71641 gaagaaataa ataaattaag agaagaaata agagataaga gtatagagct aatagtatta
    71701 aagcaaccaa tggcaaggga cttaagattt atttattcat taggtaatat atcgatagag
    71761 ttggaaagaa taggagatta tgcagcaaat atagctagag aaatgttgaa gataggtgga
    71821 gaggcttata taaaagagct gatagatatt cctaagatgg caaaagaatg taagtctatg
    71881 atgtctcaga ctagagaagc tttaatctta tttgatgcaa gtatagctta tgatgttgga
    71941 actaaagatg atattgtaga tggattgtat gaacaagtac aaattgattg tttaaaaata
    72001 atgcatgaaa attcaaatac tatagaccaa ggagtaaaac ttctacttat aggaagatac
    72061 cttgaaagaa ttggagacca tataacaaat gtatgtgaga agataatttt tgcaattgag
    72121 ggtaaaatgg ttgagatagg ataaaaaact gctttaaagc agttttttta ttgtctaaat
    72181 taagaaagaa ttgataaaaa aatatgatta atgggtaaat ttaaaaaatt gtgatatact
    72241 aggaacatat taaatatgag gatgcgtatt ttatataagg tgctttttag gaggtggaac
    72301 tttgaaactt caaaagatgg gtatgaggac tataaaaaca ggaattagtg tcactttatg
    72361 tatgattctt ggtaactatc tagtagagaa tatgttttat tctctagtag catgtataat
    72421 ttctgttcaa gatacggtaa aaggttcttt aaagacagga atcaatagag tggaaggtac
    72481 tattttaggt ggtataatag gattcatatt tgccatcatt aaagctggag accctttttt
    72541 atgtggtcta ggagtaatgt gctcaatata tttatgcaat ctgtttaaaa taaagtcagt
    72601 agtagttgcc tgtgtaacct ttctggctat acatctaggt gtaggaaata gtgaccctgt
    72661 gtattattct ttacatagag tgttagatac atctgtaggt gttttgtttg gagtacttgt
    72721 taattattat gtggctagac caaattatct aaatagtgtt atagatgaat ttaaaaagat
    72781 agaagaactt tcaatgttac ttattgaaga taaaattctt agaaaagaaa atttaaatgt
    72841 agagaaattt gaagaagaag tagaaaaatt agaagaaata tattcaaaac ttattgatga
    72901 gttggattat agtttgagtg aaactaatat agaaaaaatt gagaatgcct taaggatatg
    72961 tagagaaata cattttcata tgcagtctat agagttactt gaaaataaac tttatttgaa
    73021 agagcataca tataaatacc ttaagaaaac atataatgtg gataagctag actggaatat
    73081 agatgaagaa aaaagccccg tattcaacta tcatctaatg aaaataatga ttgaaataga
    73141 gttgttgaga aagctaaata aatcatatta ataatagtag ttaaataata aataaaaaat
    73201 agtatctttg taaatattaa acatatataa gtttaattta tggaggtact attttttatg
    73261 aatactagaa atgacaattc taaaatacta gaaatatata aaatgaagct ttttggcgaa
    73321 cttgtaaaag cagtgtggaa tgatgatata gaggatattg aaaacttacc taataaaatt
    73381 ttaaatgaag atttaaagga taatttaaat aattatttta gtggaaaatt tgataaagat
    73441 actatggtaa atttaattag ggtaactatg ggattggatg tgacagaaga tacagataaa
    73501 aatttaaaag agtcactaca tgaagctgta aatttagatg aagtcaaaag accaataata
    73561 tctgtaatat cagatgcttg caaatattgt gatgaaaata ataaggaaga tgagtcatgt
    73621 aagataagaa gtaagcatat taattgtaat gaggaagatg tatgtagtgc ttgtggtgat
    73681 tgtgtatcaa gatgtaagtt gggtgcaatt tcagataaaa tagaatttat accaatgata
    73741 aaattgttaa aagatataaa gagccctgta tatgcaatag ttgcaccagc ttttgtagga
    73801 cagtttggga aagatgtaag ccctggtaaa ttaagaactg cattaaaaaa gataggattt
    73861 gaagatatga tagaagttgc tttggcagca gatatgctta ctgcaaaaga agcatatgat
    73921 tattatgagc atatgaaaaa ggacgaagaa ggatgcttta taactagttg ttgctgtcct
    73981 atttgggtta gtttgataca aaatagtttt cctcagatat tggagaatgt atcaccatcc
    74041 gtttctccta tgattgcttg tgggagagct gtaaaaattt taaatccaga tgctaaagtt
    74101 gtattcatag gtccttgtat ggcaaaaaag aaagaagcaa tgttagaaga tataaaagat
    74161 gcagttgatt ttgtgcttac atttaaagag ttgcaagaaa tatttgatgc attagagtta
    74221 aatccagcaa taatggatga gagtaataga gtagaggcgt ccctttcagg tagagtttat
    74281 gctagaacag gaggtgtaag taaagcagtt aagttatcag tcagaagaat tgacaaaaat
    74341 ataaaatttg aagaaaaggc atttgaagga acaaaagagt gcatggacgg tctaaagaaa
    74401 gttctaaata aagaaataga agctacattt atagaaggaa tggggtgtgt aggaggctgt
    74461 gtaggaggtc cgaagcgtat tttaagtgtg gaagaaggta ctaagaatgt tgatgaatat
    74521 agtgaaagta cgaatatgga aactccattt gataatttaa atgtattaca atttttaact
    74581 tctttgggaa tcaaaagagt agaatcttta ggagaaaaag aagaagaaaa ggttaaaaaa
    74641 atatttagta gagatataaa aagtaataag aaagagaata aatataaaaa ataacttttt
    74701 aagtcttaaa cttatgcttt tataaaaggg agatatgggg gatgaaaatt aaagataata
    74761 aggctgtttt tcatgtattt ataaggatat ttcttatagc tgttttaatt ttaactggaa
    74821 cattattgga ggaaaaaatt aataatgttc cagttgaaaa tataagttca aaaggtgaaa
    74881 atacactgga actgctttct caaagtaata ctttaggaga aatcatatac aaagcatctc
    74941 aagaagaaac aaaaggtcca ggggctactt ctgaaaaagt agcatacata acaatagatg
    75001 atggtccatc aaaatataca aatgcactac ttgatatttt aaaagaaaat gatgtcaaag
    75061 cgacattttt tatgcttaat caaaatatga aaaatcacaa ggaagaagta aggagagtct
    75121 tggaagagga aaactcaata ggttttcata gtgtaagtca tgatatacat aagttatata
    75181 aaagcccaga agtaacagtt ggggaattta atacatgcaa taatactcta caagaaataa
    75241 ctggtcagag ttcaaaatta ataagattac catacggaag taaaccatat atgccagaag
    75301 gttcatataa taaacttatg gcaaatgatt atttaatttg ggactggaat ttggatacac
    75361 aggattggaa gtcttctaca agtcagatag taagtaatat attatattat ggaagaaaaa
    75421 gagatgaatt agtagtatta attcatgaga aagagcaaag tttaaatgct ttaaataata
    75481 ttataagaat cttaaaagag agaggatata caatattgcc aattacagaa aatataacac
    75541 ctaaaaattt ctggcaagaa aacttataat aaatttaaat atagtaaaag ataaagtaaa
    75601 ttatttataa aataaaacat ataatataaa aaatacgaat aagaggtata ctgtaaggat
    75661 aatataatat aaaattaatg agaaagcatt aaaattaaaa taaaataatc ttgcaattat
    75721 tgacattata agacagaata actgtaaaaa catattttaa aatataacaa ctatataaaa
    75781 gagaatagac ataattaaga aaattcagaa aaaataaaat aaaaataatt gacaaagaga
    75841 ataatatttg tatataataa tatgtaatat taaagactga gaagaagagg agtaagtaaa
    75901 tactactaaa agagaggaaa attcactggc tgtaagattt tctaagtata agatttactg
    75961 aatgtagctt tggagtttct aaactgaact ataagtaagt ttagacggtt agaaccgtta
    76021 aattctttga gagtcaaagt tgataaaata acattaacta ataatttaat tatatgttaa
    76081 tgtattttaa gctttggaat taaggtggta acgcgagctt ttcgtccttt ttaaagagga
    76141 tgaagagctc ttttttattt ctaaagatat ttaaaaaatt tatttataaa atacaggagg
    76201 caggacaatg gaaaatacga atttatcaaa aacttataac ccaaaagatt ttgaggctag
    76261 gctatataaa aaatggatgg atgaagggta ttttaaatct aaaccaaatc cagataaaaa
    76321 accatttaca ataatgatgc caccaccaaa tataacaggg caattgcata tgggacacgc
    76381 tcttgaccat acacttcaag atatattaat cagatggaaa cgtatggatg gatatgaagc
    76441 tttttggctt ccaggaactg accatgcttc tatagcaaca gaagttaaag ttgttgaaag
    76501 aataaaaaaa caagaaggca agacaaagta tgaaataggt agagaagaat ttttaaagag
    76561 agcctgggaa tggaaagatg aatttggagg aaaaatatct aatcagctta aacaactagg
    76621 tgattcttgt gattgggata aagaaagatt tactatggat gaagggtgta atgaagcagt
    76681 tatagaattt tttgtaagcc tatatgaaaa aggtcacata tacagaggaa atagaataat
    76741 aaactggtgc ccagattgca aaactacttt atcagatgca gaagttgaac atgaagaaca
    76801 cgacggaaac ttttatcata taaagtaccc actaaaagat agtgaagact ttttagaaat
    76861 agctacaact agacctgaga caatgatagg agatactggt atagcagtaa atccagaaga
    76921 tgatagatat aaacatttaa taggaaaaac agcaatactt ccattagtag gaagagaact
    76981 tccaatagtt gcagatagtt atgttgattt agagtttgga actggtgcag ttaagatgac
    77041 tccagcacat gaccctaatg attttgaagt aggattaaga cataatcttg agcagttaaa
    77101 tactatgaat gaagatggaa ctatgaatga agtttgtgga aaatatgaag gtatggatag
    77161 atttgagtgt agaaaagcta tcgtagcaga cttaaaagaa caaggttacc taattaagat
    77221 aaaagcgcat aatcataatg taggaacttg ttatagatgc catacagtag ttgagcctag
    77281 attatcagag caatggtttg ttaagatgga agaacttgca aaaccagcta tagatattct
    77341 taaaaaagga gaattagaat ttgttccaga taaatttgat aaaacttatt tacaatggct
    77401 agaaaatata agagattggt gtatatcaag acaattatgg tggggtcatc aaataccagc
    77461 ttattattgt caagagtgtg gagaaatagt agttgctaga aaaatgccag ataagtgtcc
    77521 taaatgtgga agcactcatt ttaaacaaga tgaagatgcc ttagatactt ggttcagttc
    77581 tgcattatgg cctttctcta ctctaggatg gccaaataag actgaagctt tagattatta
    77641 ttatccaaca agtgtacttg ttacaggata cgatataata ttcttctggg tagttagaat
    77701 ggcatttgca ggtatgttct gtatgaatga aaagccattt gaccatgttt tggttcatgg
    77761 attagtaaga gattctcaag gtagaaaaat gagtaaatct ttaggaaatg gtatagaccc
    77821 attggagata atcgagcaat atggagctga tgccctaaga tttacattaa caactggaaa
    77881 ttccccagga aatgatatga gattctatat ggaaagagta gaatttgcta gaaactttgc
    77941 aaataagttg tggaatgcat caagatttgt atttatgaat attgatgaag atataattaa
    78001 aaacatgact agagaaagtg ttaaagagga cttaactcta gctgataaat ggataatatc
    78061 aagagcaaat aatattgtaa aagaagcaac taataacatg gataagtttg atttaggaat
    78121 agcacttcaa aagatatacg attttacttg gtcagaatac tgtgactggt atattgaaat
    78181 ggttaaacct agattatatg gggaagatgc aaatgctaaa tctgcagcat tatatacatt
    78241 aacttatgtt cttgaaaaaa tattaaaatt attacatcca tacatgccat ttataacaga
    78301 ggaaatatat actcatcttc ctactgttga aggatgtata atagtatctg aatggccaaa
    78361 atataatgaa gaagataaca tggctgaaga agaagatatg atgaacttat tgatggaagg
    78421 tataagaagt ataagaaatg tgagagcaga aatgaatgta ccaccttcta agaaagctaa
    78481 attgataata atcccaagtg aagaaaaaat agaagctatt gagcttggta aagactattt
    78541 tataactcta gcatctgctt caaatgtaga gatagcaaaa gataaatcta atgttccaga
    78601 agatgcagtt ggagtagtta ttgatggtgt tgaaatattt atacctctta atgaattagt
    78661 tgattttgaa aaagaaattg agagattgtc taaagaaaag aaaaagttag aaggcgaaat
    78721 aaagagagtt aatggaaagc ttgcaaatca aggtttctta gcaaaagctc ctgaaagttt
    78781 aattgaagaa gaaaaagtaa aaaaagaaaa atttgaagag atgattaaat ctgttgagga
    78841 aagattaaca aatttagaat ctaaaataaa ataaatataa gaattagtaa aaacatacaa
    78901 aaagtatata ttctatactt tttgtatgtt tttctttata tatatacaaa tatgatgtta
    78961 taattcttta cagatgtgtt atatttttat tttatgttgt gaatatatga attttatgtc
    79021 ttaaaattta taagcaataa aaatttgata tattatgatg tttaatatag ggtaataaat
    79081 acatattata tttattttac tatatttttt tacataatat atctagaaaa gtataggaat
    79141 ttatcgtaat ttaagtttaa atattaaaga gaatttctat aagtagttta atcgacaact
    79201 taaatttata aagaaattta aatttgaaag ctagtgagta cagtttggaa attgaaataa
    79261 agtaaactaa atgatatttt agatttggag gtgatattat gttcagggta gttatatgtg
    79321 atgacgaaaa aatacaaaga agcatactaa aagagtttac aaaaaaactt ttgtctgaaa
    79381 gatgtctaaa ttatcaaata ctggaatttt cctgtggaga agatttaata tccaaatacc
    79441 cagaaaaaat tgatattata tttttagata tccaaatgaa agatatcaat ggaattgagg
    79501 tggctaaaaa aataagaaag tttgatgaaa aagtagaaat tatatttaca acagcttttt
    79561 cagagtatgc cccccaaggt tatgaggttc gtgcttatag atatttagta aagcctatag
    79621 agtatagtaa ctttgcaatg ggtgtaaatc tttgtattga taaccttcaa agaaagaagg
    79681 agcgttatat agttttaaat agtaaaaaag gatttaatag aatactgata gattctattt
    79741 tatatgttga aactgtaaag agagatttag ttgtacatac aataggtaga gattataaag
    79801 ctaatatgag catgaaacaa gcagaaaaat tactgtgtga aaatggcttt tttagatgtc
    79861 atacaagttt tattgttaat ttaagaagaa tagaagatct tagggataat atgattacta
    79921 ttaatgaaca atttatacct ataagtaagt atagacttaa agatttaaaa gtagcattaa
    79981 caagcttgtt atgtgatata atgtattaat tttaaaaagg taattgaaaa tatcgtaaaa
    80041 aagatttaat gtcatcacag ggctattgat taaaactgtc ttaatatata aaatgttatt
    80101 tatattaaga cagttttatt atgcaaaata tcagtttata gacttttaat attgtttaat
    80161 atgtatatgt agagtttcca ttacagtagc atgattatta attagtagcc tgattattaa
    80221 tatactatta ttgattttta tatgcattat atgtattttt agaatatgat taccttttta
    80281 aaataatgac tatttataaa actctataga tatttgtttc atttagctat gcatacttta
    80341 attaattata ttaatattta atggagtata atataaatat taaagcgaca tcttatagtt
    80401 tattgaacct atagtaatga attaataaat ggtttaattc tatgaaaaga tttcctttta
    80461 tgcaatttat ttattgaaat atgatataat atataaaggt gtaagtatta gttgttaaaa
    80521 taatatttat attagttttt atgcatactt ggtataagtt tttcatatat tggttaaaat
    80581 tgatgttgat ttattatttt tagtattttt tcaccttttg attcatactt tgtagaatgg
    80641 tgtattttat aaaactgatt ataagacaag ttcattcaaa ttagcatttt tatatcatat
    80701 aaataattgt tccccctaaa taagatttag atatatagta ttaaaatcaa aaagtataaa
    80761 ataaaattga tgcttaatca tagataaata ttaataaaat atacaagggg attgtctaat
    80821 aaaaagataa tctccttttt tacaaataat cctaaattgt gatataaatc taaaaatttt
    80881 atcttaacat ttaaccattt aatgataata attgatataa taaatataaa ttaaatatat
    80941 ggtgtactta ttttatgttt ttagcaagaa atatagcatt taaaagataa attgtgcaac
    81001 ttaaatcaaa gtttaagatg aactattaac atagatatat taaaaacttt tgtaatggag
    81061 aatatatgtg atatgaataa taaagttaag gttgcagtat tagatacagg aatagacaaa
    81121 gaacatgatt acttaaaaga taatttagtt ggaggaattg cttttgaatg tatgcatgat
    81181 tatatcttta tatcagataa atttgatgat gaagatggtc atggaactgc ttgtgcatca
    81241 ataataaaga aagagtatga agatgtagag ttatttgtaa taaaaatttt gagaaaagat
    81301 ggtattacaa atataaaagt tcttgaagaa gcattaagat accttttaga cactaacata
    81361 agattaatta atttaagttt atcagtcata ggagtagaga gtgttaaggg cttatttgaa
    81421 gtttgttacg aattgtttag aaaaggaaaa ataatagtat gttcactcgc taatgatttt
    81481 gatttaagtt atccagctat gtttaacaat gttataggtg taagaggatt tactttagat
    81541 ggagatgatt cattttggta caacaaaaaa tatgatgttc aatgtgttat ggatagcaat
    81601 tcatatataa gttgtgatat aaataattcc tatagattac caccaaaatg taatagttat
    81661 ttatcagcaa agcttactgg taaaatagct aagatattat cagaaaaacc aggcataaca
    81721 atatctgatt taaatgataa gcttgaatca ttagcaacta gaaatcattg ggatagttgt
    81781 gattttgatg agtgtagtag aattgtaaac tttaaattgg atttgtatga caaagaaaat
    81841 gctcttctta tgaaagttgc tgacgttgtt agggattgtt tagatattga agataataat
    81901 gaaaaactct ttaagggtag cctttttaat aaggagatag gtttggttta tgataattgt
    81961 tttaatctgt tgaaaaagct agagcataga tttgacataa agtttaatta tatggacatc
    82021 tcaaaatatg acttagtttc aatatataca ctgactgaat tagtggaaag atataaaaac
    82081 ttataaataa agatttgtag ctaaatttaa tgtagaaggt attaaattat atgtattctt
    82141 tgtcggtaga ttaaaagtaa aaaatatact ataattagat agcataagag aaaatgccaa
    82201 tacaggggga gttagataat gaaatatgaa gaagcattag agtacatatc acaaactaat
    82261 aaattcggta taagattagg attagaaaat atcggaaagt tattagaatt attaggaaat
    82321 ccacaagaaa ctttgaatat aatacatgta gctggaacta atggaaaagg ttctgtgtgt
    82381 tcttttgttt ctaatatact aagagagtgt ggatataaag ttggtttata tacatctcca
    82441 tatttagaaa cttttactga gcgtataaga gtaaatggac aaaatatacc acaggatgat
    82501 gttgctagaa taattgagtt aataaaagaa aaaatagaga ttatggtaaa agaaggctat
    82561 gcatatccaa cagaatttga agtggttact gcaatggcat tttattacta ttcagaacaa
    82621 aaggtagact ttgtggcatt agaagttggt ttaggtggca gatatgatgc tacaaatata
    82681 ataacaaaat cacttgtaag tgtgatagta tctataagtt tggaccatac aggtatactt
    82741 ggagatacaa tagaaaaaat agcgtacgaa aaggctggaa taataaagga aaatggagta
    82801 gtactagtat atgaccagac tgatgaagcg aaggatgtta taaagtcagt ttgtaaagag
    82861 aaaaaagcta aatatataga agttgatttt gatgatataa acataaaaaa atcagatata
    82921 aattctcaaa tatacgattg tactgtaatg aaagaaactt atagagacct tgaaataaaa
    82981 ttgataggtg aacatcaaat aaacaattct atcttggcaa ttagtgtaat aaaatatcta
    83041 aaagacataa ataaattagc aaatataaat gaagaatcta taagaaaagg acttataaat
    83101 actaaatggc caggaagaat agaaaagata aaagaaaatc caatttttat aatagatggt
    83161 gcacataatg aagatggagc aaaatctttg gcaaaagcac ttgataagaa ttttaaaggt
    83221 agaaaattaa ccttattaat aggtatgtta gaagataaag atattgatag tgttttagag
    83281 atattgttgc cacattttaa taaggtaata acaacaacac caaataaccc aagggccata
    83341 aattcagata tattaagaga aaaagtatta aaatatgtag atgatgtaac atcaaagcat
    83401 gagatagagg atgcagtaaa ttatacatta gaaacatcaa gtgaggatga tattataata
    83461 agtgcaggtt cattatatat gattggtaca gtgagaactt tagtaaagaa attataattt
    83521 tataaaataa atatacaaat aaagatataa aaaagagttg tctaaaaaat ggacaactct
    83581 ttttatataa agtaagtttt taataatttt actgatgttt atataagtaa ttatatagat
    83641 tgacgtatag ccttagataa ttggtctggg caagaagtac cttttccacc acagtcaata
    83701 ccgtttaatt tatcagcaac ttcaagagca ttttggccga ttattaagct tctaagtcct
    83761 gataaattac cattacatcc tcctataaac tcagcatcaa caatcacatt attttcatca
    83821 acttcaaaaa tcatttctct acaacataca ccacttggat taaatgttac tttcattaaa
    83881 aagacctcca ttaaatatta tttctttttt taacaataat aataatacca aatatatgcg
    83941 taataatgca actataaagc ataatacaag ctaatgaaat aatatattat tgtagtatat
    84001 gtattgtaga gaggaggggt tatatgaaaa tctatatttc taactactta tcaaagagta
    84061 ttagcatagt tgattattct acacttgaac tagaaaaaga aatagtatta gaagataata
    84121 tatatccaca ccatttttgc atagaaaaag aaaaaaattt aatatacata cctagttcaa
    84181 gtaatgggat actttatgtc ttagatttaa gtaatgataa aataattgat actgtctcta
    84241 taggaggaag tcttagtcaa gttgtactta gtgataatga attgtttgtg gcaaatgaag
    84301 attctaatag tatatatgta ctagataaaa acacattaaa tccaatagga attattggag
    84361 ttgataatat gccacatgga tttgactttg atagagaaag taaaaaatta tatgtaccgt
    84421 gtataaactc gatagtatgt atagatacaa ttaataaaaa tatacaaaag aaaataaata
    84481 tggactttag agcttggcat atagagcttg ataaacaaaa gaaagaaatg tatatatcaa
    84541 cacttgatgg aaagcttata ataatagatg aagtaagcat ggatataaaa aaggtattat
    84601 atgaattttt attaccagta gaaataagat ttaattatag tggcaaaaaa gtttatgttg
    84661 ctgatttggg ttataataat gtaagaattt tagattatac aacgagtaga tacattggaa
    84721 atattgaaat aaatgggatt cctcaaggct tagaaatatc taaagatgaa aagctactat
    84781 ttgtatcaga tacacaagaa aattcagtaa aagtttatga aactgcaaac aataaattaa
    84841 taaaagaaat caaggtagga aaagagccta caactataat ttgtttgtag gctttaatgt
    84901 atgtctctta taagtaaatc gataacttcg gcatacatat aagatgcatt atttttccag
    84961 ttattgcaaa taagttttgc ttgtttctct gatgaaacat ttagatttaa atctattaag
    85021 ttagactgat tttctatgac tctaaggttg acaataaatt cattatcact ttgttttaca
    85081 aaactagact ttacttgagt atctgctagt agattttctt tgttagaatc tatatacttg
    85141 tctatttttt cagtaacact agtaggtatt cgattaaaga agtattctag actttctacg
    85201 cctctttgag taagagcata atattctctg tcagagtctt tatatgtagt caaaaactta
    85261 gattccataa gctgagataa aagctgttgt aatgaaaaat aattcatcat ctcagtctct
    85321 aatactactt gagttatttg agaattagtt aaatccattt taattttttc taatatatat
    85381 aaaattaaaa gtttgtgata ggctaattct tcagacgagt tttcaaacat aaatatcatc
    85441 ctccgtcaaa ctatttctat atataatata ttaaactaat ttgtacaaaa ttaaaagaac
    85501 aatttgtatt gtattattaa tctttaataa ttcatataaa acaattttat aaataaatat
    85561 agagaaacag ggctgctaat tagcagccct gttgataccc aggtgtcaaa atttactatt
    85621 tattttccag ccatttgtct ttcagccatt tcaactaatt tcttagtcat atatccacca
    85681 acatatccat tttctctagc tgttaagtta cctttatcta tgttttcata gttagataaa
    85741 cctatttcgt tagctatttc taatttcatt tggtttaaag cagcttttgc ttctggaact
    85801 actgttctgt ttgaatttga catagtaaat ttcctcctca aataattagt ttatgatgtc
    85861 taacaacact tttatttatg tgatgttaat actaatttct ccaaaataaa aataatatat
    85921 acagaaaaat aaaggtaaaa atgtaaaaaa tataaaaaaa ttaaataaat gagtatttta
    85981 gagagtttaa ttaggtcaat ataggtttta tttttttagt tattgtctta taaattaaat
    86041 attacagtac ttttttgagc tgaaaaaaaa taaattttaa atatagaaga aattatttca
    86101 aagggggaat agtatgaaaa gagaagttaa aaggactaaa gctttgatat atagtgtttt
    86161 atttttttca ttattattag tgttaatatt tgtttttgtt tatggaataa aatacatatg
    86221 ttctaaatac gacaattcaa aaatgcctat atataaagtt gatacaaatg agaaaaaaat
    86281 agccttgagt tttgatgtag catggggaac tgataatatg gatgatattt taaaaatttt
    86341 agataaacat aatgtaaaag ctaccttctt tttagttggt agttgggtgg atgataatga
    86401 agaaattgta aaagctatag atgaaaaagg acatgaaatt ggaaatcatt caaacactca
    86461 tgccaatttg aaggaaatat caaaagaaga cataacaaaa gagatagaaa ctacatcaga
    86521 aaaaatatat aatataacag gaaaaaagac taatttattt agacctcctt ttggggacgt
    86581 aaacaataaa gctatggaca tttgtagtga tttaggttat aaagtaatta agtgggatgt
    86641 agattctata gattggaagg agcttggacc aaatcatgta attgagaaag taataaaaga
    86701 atctcaacct ggttcaatag ttttattcca tgctaatata aatgatgtag ataactattt
    86761 ggatactata ataagtcgac taaaaaaaga tggatacagt ctagtcaaaa tatctgattt
    86821 gttgtataaa gataattatg tagttgattc caatggagtg caaaaaacta agaattaata
    86881 agtaataaat gtatatttta agtaaagttg tgataaatta tatagtatat gttagaaaag
    86941 tgtcgataaa aagacggtgt ctattttttg acacttttta tacatgtatg caatatcaat
    87001 aattatagat taaattgatt aaaaaagtgt ctaataattg actttttttt gatggattta
    87061 aaaatttaga agaattaatg aatgctgtaa gacagtattt ccaaagggta taagtttgtt
    87121 taaaagttgg catagaaatt gctttgttaa taagcgatat gttctataga aataaacaat
    87181 atgttaagac cttataatag aaaaatagca ttaacattat ttgaacagct tataaaaaaa
    87241 ttaatatact taagggggcg tactagttga acaaactata ttctatttta ttaaaacaac
    87301 acgttggtgg tccagataag ccagtagtaa gtgttggaga tgtagtaaaa aaaggaactc
    87361 taatcgcaga accaactgga ttaggggcaa atatttatgc cagtgttagt ggaaaaataa
    87421 gtgaaataaa tgaccaagcg atagtaattg aagctgatga agtacaagaa gatacttttg
    87481 aaccattaaa aggagaaggt atacttgact taattaaaga agctggagta gtaggaatgg
    87541 gtggagcagg attccctact catgtaaaat taaacataga tttaaatggt ggaacaatat
    87601 tagcaaatgc agctgaatgt gaacctttat tagctcataa tataaaagaa atagaagaaa
    87661 gaccagaaat agtttatcaa ggtataaaat atgctatgga agttactaat gctggaaaag
    87721 gtatgctagc aataaaaagc aagcatccaa aagcaataga agctttcaaa aaagtaataa
    87781 agccaggaga caacatagaa gttgcagaac tagttgatat gtacccaatg ggagaagaga
    87841 gagcaatagt aagagacgtt ctaggaaaat tacttgagcc aactcaatta ccttcagagg
    87901 ctaatgcagt agtaataaac gtagaaacac taactagaat agtagaggct gttgagcaaa
    87961 aaagaccagt tatatctaaa aatataactg tagttggtca attaaacagt ggaaaagagt
    88021 ctatagtatt tgaagatgtg ccaattggaa caactgtcgg agaattaatt gaaagagctg
    88081 gtggaataaa aggtgaatat ggtgaaataa tcctaggagg acctttcact ggtaaagcta
    88141 ctactttaga tgctccaata actaaaacta gtggtggtat aatagttact atgccatttg
    88201 ttaatgaaaa gagaaaaatg ggtcttttag tctgtgcatg tggacctaat gaagagagaa
    88261 tgagagatat agcaactaaa atgggagtta ctgatatagt atcagttcaa aaatgtaaac
    88321 aagctcaaga aattaaaggt gcattaaaat gtgaaaatcc aggacactgt ccaggacaag
    88381 ctcaaaaatg tattgaattt aagaaagctg gagcagaagt tatattaata ggaaactgta
    88441 ctgactgtag taacacagta atgggttctg caccaaaatt aaagttaggt gtatatcata
    88501 ttactgacca tgtaatgaga acagttaatc acccattaat aagaagaata aaaggtgacg
    88561 taagattaaa aataaaataa tagataaata gaagttagac atctttagaa gtaaaactta
    88621 aaaattactt ctaaggatgt tttttaatgt attttgaggg caatatatag ctttaaaaga
    88681 aatcaaaaaa gtgccaaatg taaaactaat taaaccatat atatttaaga agggattgaa
    88741 ttggagttgt gaattatgtt agtagaaacc attctaagtg tttgttattg gtacatttga
    88801 tatttgtatg taaatacaga aaaaactttt tgctcagatg gatactttgc tttcagtgta
    88861 ggaaatgttt ctaaagaaat gattgaaaaa tacatacaaa gtaagggata ggtttacatc
    88921 caccaaccta aaggtatagt ggttttacgc cttaatttat aaaaagaaat taatttatat
    88981 tattattaag tttaaaataa aaagtctcaa attgatttat aagtcatttt gggacttttt
    89041 tatgtaaata taatatgcaa atatagtttg tttaaaaata tctattttaa ttatattctt
    89101 aaatttatga ttggatacag gcattcatta attgtttgat gaatagaaaa atgttttgaa
    89161 ggtgaaaata gtattgaaaa aataatatac taagggtata attcatttga tttcatttgt
    89221 ataaatttaa ttataaattt taaagtgatt atataaattt aaatgctaat tacttaataa
    89281 attttaataa taattattta ataaataatt attataatat gctagaataa atatatataa
    89341 ataagttttg atgaggtact actataaagg gggggacttt atgttttcga taccagaagt
    89401 aaaaaaagta gaagaggtaa tggatacaaa atttacaact atagacgaag acacaagaat
    89461 tgaagatgca ataaaagaaa tgataaaaag caacacaaaa actctaatgg taatagattc
    89521 atctgaccaa ttaaaaggca ttatatccat gacggatata cataatcttt atgagatgca
    89581 taaaaagtat gaaggtcaac cagtaaaact tataatgaag aaggatgtaa tatatgtcaa
    89641 cgaaggttta accttagatg aatgtagaga tataatgata ttaaaaaata tagggattct
    89701 tcctgttctt agagataata aaattattgg agttctaaaa caagagcaca ttagggacta
    89761 tctatatatg catttagaag attatggatt gactttgaag tatattatag gtcaaattaa
    89821 agaaggaatt tgtgctataa ataacgaagg tgttgttatc ttgtggaata agtttatgga
    89881 ggaaaggtat gatataaagt ctgaagatat agttggtcga ccgatgaatg aatttttgga
    89941 aaatactatt tcagaaaaag tactaaatag taaagttgga atgagtgact tgtattttac
    90001 agataaaaaa gaaaatatgt atgcattagt tcatgcaaat cctatatttt ataaagaaga
    90061 atttatcggt gttgtatgta cagaagttga tgttacagaa gctaagatat tagctcttga
    90121 acttgaaaaa gtaaatgata cattaaaata tctaaagaac gaagtcaaaa atttatctaa
    90181 aggtagtttt gataagattt taggtaaaag ttataaattg gaaaaatcga aagcgattgc
    90241 aaaacaagtg gctagaacaa atagtagcat atttatttgg ggtgaaagtg gtacgggtaa
    90301 agaagtattt gcaagagcta ttcatgatta tagtgagaga aaaggtcaat ttatacctgt
    90361 taactgtagt gccataccaa atgagttatt tgaaagtgag ttttttgggt atgaatcagg
    90421 tgcatttaca ggagcaagta aaaagggtcg aataggtata tttgaacttg caaaagatgg
    90481 aactgtattt ttagatgaaa ttgccgattt acctcttagt atgcaagcaa agttgcttag
    90541 agtattacag gaaaaagaaa taagaagagt tggtggagat accacaataa aaataaatcc
    90601 tagaataata tcagctacca ataaagattt gagtaaaatg gtaaaggcag aaaaatttag
    90661 agaagattta tactatagat taaatgttgt tgaaataaag attcctccac ttagagagag
    90721 aaaagaagac ataggattat tggttcatag ctttttagag gagatatgta aacaaaataa
    90781 taagcctgtt cttacaatta gcaaagatgt aatagatata tttcagaatt atagatggaa
    90841 aggtaatatt agagaattaa aaaatacgat tgaaaatatt gttgtattgt cacaaaattc
    90901 taaaatagat gtagatgatg taccaagtta tatgatggat tctacaaata atagtactga
    90961 agaagaagag tatcccttag atttaacgaa ggcaactcaa aaaattgaaa taaagaatat
    91021 aaccaaggca cttaaaatgt ctaatggaaa taaagctaaa gcagctaaga tattaaatat
    91081 acccagaaca actttgtatt ataagataga ccaatacaaa atagatgtgt ctaaaatatg
    91141 acatatgact aaattttgac aaaatgataa actttaattt aaaacctagt aaagccaaca
    91201 cttgtataag tgttgtgtat atagatgtgt taaaaaaaat gaaaaagtgt tgattaattg
    91261 acactttttt tgtttgagaa aatgtttaca aatacaaaaa ataacatatt ttaaataaat
    91321 atttatataa tatttggcta aaaatagcga tagatgaaga atctattata gaaaaaatct
    91381 ttttgttaat aagttggcat aggaattgct tataatataa agtgactttg agtgagaaaa
    91441 aaataatatt aatcataaca aattatgtag gttttaattt acttaatttc tcagttaagg
    91501 ggttacctgt tgaggaattg agatttaaaa taataaataa gaaaataatg taaggaggta
    91561 ttttatacta tgtcaataac tttagaaaca gctcaagccc atgcaaatga cccagcagtt
    91621 tgttgttgta gatttgaagc gggaacaatt atagcgccag aaaacttaga agatccagca
    91681 atatttgcag acttagagga ttctggatta ttaacaatac cagaaaatgg attaactata
    91741 ggtcaagtac taggagctaa gttaaaagaa actttagatg cactttctcc aatgactaca
    91801 gataacgtag aaggatacaa agcaggagag gctaaagaag aagtagtaga agaaacagta
    91861 gaagaagcag ctccagtatc agaagcagca gtagttccag taagcacagg agttgcaggt
    91921 gaaacagtta aaatacacat aggtgaaggt aagaacataa gcttagagat acctttatca
    91981 gtagctggtc aagcaggagt tgctgctcca gtagcaaacg ttgctgctcc agtggcaagt
    92041 gcagcagcag aagtagctcc aaaagttgaa gaaaagaaac ttttaagaag cttaactaaa
    92101 aaacacttta aaatagataa agttgaattt gctgatgaaa ctaaaataga aggaactact
    92161 ttatacatca gaaacgcaga agaaatatgt aaagaagcta atgaaactca agagttagtt
    92221 gtagatatga agttagaaat aataactcct gataaatatg aaacttacag tgaagctgta
    92281 ttagatatac aaccaatcgc tactaaagaa gaaggcgaat taggttcagg tataactaga
    92341 gttatagatg gagctgtaat ggtattaact ggtacagatg aagatggagt tcaaataggt
    92401 gaatttggtt cttcagaagg tgagttaaat actactataa tgtggggtag accaggtgct
    92461 gctgacaaag gtgaaatatt catcaaaggt caagtaacaa taaaagcagg aactaacatg
    92521 gaaagaccag gacctttagc tgctcaccgt gcatttgact atgtaactca agaaataaga
    92581 gaagcattaa agaaagttga caactcttta gtagttgatg aagaagtaat agagcaatac
    92641 agaagagaag gtaaaaagaa agttgttgtt ataaaagaaa taatgggaca aggtgcaatg
    92701 catgataacc taatattacc agttgagcca gttggtacat taggagctca accaaacgtt
    92761 gacttaggaa acatgccagt tgtattatct ccacttgaag tattagatgg tggtatccat
    92821 gcattaactt gtataggacc tgcatcaaaa gaaatgtcaa gacattactg gagagagcca
    92881 ttagtaataa gagctatgga agacgaagaa atagatttag taggtgttgt atttgttggt
    92941 tctccacaag taaatgctga gaaattctat gtatctaaga gattaggtat gttagttgaa
    93001 gctatggaag ttgatggagc tgtagtaact actgaaggtt tcggaaacaa ccatatagat
    93061 ttcgcatctc acatagagca aataggtatg agaggtatac cagtagttgg tgtaagtttc
    93121 tcagctgttc aaggtgctct agttgttggt aataaataca tgactcacat ggtagacaac
    93181 aataagtcta agcaaggtat agagaatgaa atattatcta acaacacttt agctccagaa
    93241 gatgctgtta gaataatggc tatgcttaaa aatgctatag aaggtgtaga agttaaagct
    93301 cctgaaagaa aatggaatcc aaatgttaaa ttaaataaca tagaagctat agaaaaagtt
    93361 acaggagaaa aaatagtatt agaagagaat gagcaatctc taccaatgag taagaagaga
    93421 agagaaatat acgaaaaaga cgaaaactaa aatttagata ctaactaaga tttagacaat
    93481 aacataaatt tagatccaag tttaaaacag tatagagagg tagaattata atggataggt
    93541 taaaatatat ctcatcagag actttttatg aaggtattat agttgacatc aaaggtggtg
    93601 gagtgactat agacctaaaa ggtagacttg gacaatttaa aatacctaat agaatgctta
    93661 taactgacta cgaacttaag ataggtcaag aagttggatt catgctaagc tatcctgagg
    93721 tattaagtcc agagcctaat caagagtatg tagaaaatat taggagagaa aaagaaaaac
    93781 aagcagaaat gcaatcaaaa caagaagaaa aataataaat aatcgtttga aaatagaagg
    93841 gagaggaaat atatgagcct tacaacagta caaggacttc aatctgaaat attcgttcca
    93901 ataacacctc ctccagtttg gactcctgta actaaagaat taaaagatat gactatagct
    93961 ttagctacag cagctggtgt tcatttaaaa tctgacaaga gatttaatct agcaggagat
    94021 actacattta gagctatacc taatacagct acagttgatg aaatgatggt atcacatggt
    94081 ggatatgaca atggagatgt aaacaaagat ataaactgta tgttccctat agatagatta
    94141 catgaattag ctgcagaagg atttatcaaa ggagtagctc ctatgcacta tgcattcatg
    94201 ggtggtggag gaaaccaaca tgtcttcact gaagaaactg gtcctgctat cgctgctaaa
    94261 cttaaggaag agggagtaga cggtgtagtt atgacagctg gctgaggtac ttgccataga
    94321 actgccgtga tcgtgcagag agcaatagag gaagctggaa tacctacaat aataatagca
    94381 gctcttcctc cagtagttag acaaaacgga actcctagag cagttgctcc attagttcca
    94441 atgggtgcta atgctggtga accacataat atagaaatgc aaacacatat attaagagat
    94501 acattagagc aattagttgc aataccatct gctggtaaga tagttccatt accatacgaa
    94561 tataaagctc acgtttaaaa tgtaatttat atttgaaaat atagaaccct tctcctacac
    94621 ggttaggaga ggggttttaa gaacaaaggt ggatattatg gaagaaaaaa taatgagaag
    94681 acttgttata aaaccgtttc atatgaatga agttaatttc ggttcaaaaa cttctataaa
    94741 gaaagatgta cttacaatag atttatcaag tatagatgaa ataaaagaaa gagaagagtt
    94801 aataacagac ataaaagtag acattataaa acctggagat tatgatagag aaattaatac
    94861 tattatggac attataccaa tatcaacaaa agttttaggc agactgggag agggtatcac
    94921 acatacttta acgggtgtat atgtaatgtt aactggtgca gatgaagatg gaaatcaaat
    94981 gcatgaattt ggttcttcag aaggaatttt gaaagaccaa atggtatttg ggagatatgg
    95041 aactccatca gttgaagatt atataatcca tgtagatgta actttaaagg gaggtttacc
    95101 ttttgaaaga acacttccac ttgcagcatt cagagcatgt gatgatttta tacaagaaat
    95161 aagagcgtct ttgaaaatgg aagacggaag aaatgctact caagttcgtg aatattttga
    95221 caaaattcga ccaaatgcaa aaaaggttgt catagtaaaa caaatagcag gtcaaggtgc
    95281 tatgtatgac aatcagttat tctcaaagga acctagtgga tttgaaggag gaacatcaat
    95341 tatagatatg ggaaatgtac ctatgattat atctcctaat gaatacagag atggtgccct
    95401 tagagctatg acttaagaga ggtggatatt atgggaatag gaccttcaac aaaagaaaca
    95461 tctcttcatc actttagaga cccactttta gacatagttg aaagtgataa ggatgtagat
    95521 ttacttggag taatagtagt aggaactcca gatggaaatg aaaataaaac ctttgtggga
    95581 caaagaacgg ccgcttggct ggaagccatg agagtagatg gagctatagt ttcatcagat
    95641 ggttggggaa actcacatgt tgactacgct aacacatttg aggaaatagg aaaaagagat
    95701 atacctgtag ttggagttac atttaatggg actcaagcta agtttgttgt aagcaatcaa
    95761 tatatggata ccatagttga tatgaacaaa tcaaaggaag gtattgagac agaagtagtt
    95821 ggagaaaaca acacaaatga aatagatgct aaaaaagctt tagcattttt aaaacttaaa
    95881 atgagaaaac atggataaaa aatttaagta agggaatgag ttttgtggga atttctacat
    95941 caatgaaaaa cacatcactt catatattta gagacccgtt actagatttg atagataatg
    96001 attctgacat agacttgtta ggagtggttg tagttgggac atcagagcac aatgaatgga
    96061 aaacattttt agcaactaga cttggaagat ggattgaatc attgcgacct gatggagtga
    96121 ttataacttt agatatggca ggaaaccagc acattgattt tacaaatgct atagcagagt
    96181 ttgtaaaatc agatatacct gcagtaggtc ttactattat gggagcagat ggattagtaa
    96241 ttaccaatcc atatttggat aaagctacca taattgatta taaaaagaca acaggctaca
    96301 tagaaacaga agtagttgga gacaatcaca tggatgaagt tgatgttaaa aaagcattgg
    96361 ctttcctaaa attaaaaatg cgtaaagacg caaaataaac ctaaggggga atttgatatg
    96421 aaatttagca gaagtataca agctatagac tctcatacag caggtgaagc aactagaata
    96481 gttgtaggtg gaatacctaa cataaaagga aattctatgc ctgagaaaaa agaatattta
    96541 gaggaaaatc tagattattt aagaactgct ataatgttag agccaagagg acataatgat
    96601 atgtttggtt ctgtaatgac tcaaccttgt tgcccagatg ctgactttgg aataatcttc
    96661 atggatggtg gtggatacct taacatgtgt ggccatggta caataggagc tatgacagca
    96721 gctatagaaa caggtgtagt tccagcagta gagcctgtaa ctcatgtagt tatggaagct
    96781 ccagcaggaa taataagagg agacgttaca gttgtagatg gaaaagctaa agaagtatca
    96841 ttcttaaacg taccagcttt cttatataaa gaaggtgttg aagttgactt accaggtgtt
    96901 gggactgtta aatttgacat atcatttggt ggaagcttct ttgctataat acatgcaagt
    96961 caattaggtt taaaaatcga acctcaaaat gctggtaaat taactgaact agctatgaaa
    97021 cttagagata taataaatga gaaaatagaa atacaacatc caactttagc tcatataaaa
    97081 actgtagact tagttgaaat atatgatgag ccaactcatc cagaagctac ttacaaaaat
    97141 gtagttatat ttggtcaagg tcaagttgac agatctccat gtggaactgg aacaagtgct
    97201 aaattagcta ctttacatgc taaaggtgaa ttaaaagtag gagaaaaatt cgtatatgaa
    97261 agtatattag gaactttatt caaaggtgaa atagttgaag aaactaaagt tgcagatttc
    97321 aatgctgtag tacctaaaat aactggttct gcttatataa ctggatttaa tcattttgta
    97381 atagatgaag aagacccact taaacatgga tttattctta aataagtaat aaataaatta
    97441 ggaaattaaa atagaatagt agccacttgt cggttgctat tctatagctt ttaggctata
    97501 agattcagaa tatatgaaaa aataaaaaaa taggaggatg gattatggta gcaatcttaa
    97561 aggcattata tgtagtattc gcagcaatct ttgcagttgt gtttggtaaa gacgtagcta
    97621 aagcaaacaa agaggggaaa ctagaagaac aaagtactcc aaaagttgct gtaacaggat
    97681 ttataacaga cttctttgat acattaggaa tagggtcatt tgctccaaca atagcaatgt
    97741 caaaggcttt aaagttaaat ataccagata aaaaaatgcc tggtacatta aacgtagcac
    97801 atactattcc agttgttaca gaagcattca tatttacatc aatcatacca gttgatggtg
    97861 ttactttagt atctatggtt gtggcagcag cagttggttc atatataggt gcaggaataa
    97921 tagctaagat ggacgagaga aaaatacaac ttgttatggg tgtaacttta gcattaacag
    97981 caatattaat gttattaggt catccttgga ttaacgtatt accaggtgga ggaaatgaat
    98041 taggtcttac tggtgttaaa ttggtaatag gtgtaatagg taactttata ctaggagctt
    98101 taatgacagc tggtataggt ctatatgctc caggtatggc aatggtttat ttcttaggaa
    98161 tgtctgcaaa agttgcattc ccaatagtta tgggttcttg tgcattatta atgccagttg
    98221 caagtatgaa atttataaaa gaagatgcat atactaaaaa agcatcagtt ataatagcta
    98281 tatgtggttt aataggagtt ttcgtagctg catatatagt aaaaactcta ccaatggata
    98341 tattaaaagc attagtaata gtagttatag cttatacttc tgctacaatg ataatggctg
    98401 caaataaaaa caaaaagact gcttagttaa agactactta gtgtttatta aatattacag
    98461 ctaataataa agattataaa ctgctttaaa atattgaatt aatattttag ggcagttttt
    98521 tatttgctaa attaatataa agcaattaac atgccaatta tgtaatatat atagtgattt
    98581 agtagattta atgtaaaaaa cgttgtattt tcaaagaata aagcataatt taaagctaaa
    98641 tatttaaatt ttataatcaa taagttcaat aaatgttcat atattaatac agattaataa
    98701 aaatataagc tgtaataagt ctaatataac ttataattaa gaaaaataag tttataatga
    98761 ctcaatattc atctgaatta tttgaataaa tttaattcgt tgaagttgct tatatagagt
    98821 gaataaattt aagttatata tgacttatta attatataat aggattttta taattaatac
    98881 aaaactgaaa taggtagttt aattagtata tgtagtacaa aaagataata attttataat
    98941 tataaaagtg aaatattaaa tgaaatttat aactaaataa aaacttttaa acagcaatca
    99001 aagatttgta ataaaataca tcccttataa atatatttat tatataagct gataccagaa
    99061 atataagaat taacaattgt ggagggataa aatatgatag ctgttaaaga tgagaataac
    99121 gtagtaaact taagagggga gttagacaat aagctagaat ttagccatga gatatttgga
    99181 gaaaaatttt ataatatgaa aataaaaata aacagactaa gcgattcttt tgatatactt
    99241 ccaatgactg tatcagaaag acttctccaa gatattgacc ttgataaaca aaatttagtc
    99301 aatgtcgtag gccaattaag atcatataac aaaacattaa ataataaaaa tagattagtg
    99361 cttacagtgt ttgtcagaga aataaaaagc atagacgagg aaaataaaga ccctaatagt
    99421 atatttttag atggatatgt atgtaaggaa cctgtgtata ggaagacacc tttaggaagg
    99481 gaaataaccg atttattagt tgctataaac agaccttata ataaatctga ttatatacca
    99541 tcaatagttt ggggtagaaa tgctaaattt gcaaagaatc taaaggttgg tgatagaata
    99601 cagctttggg gtagggttca aagtagagaa tatgagaaaa aaatagatga aaataatgtg
    99661 gtcaaaaaaa tggcatatga agtatccata tcgaaaataa aaaaattgga tgaaaataac
    99721 aatgaataaa cataaaaaat agactgattt ttatgaataa aatcctaata aatttggtat
    99781 aatatcatat taaaatgtat aaagattgtt taaaaaaata ctaatgaaat atctcttgaa
    99841 tagttgctcg ccatttatta taatgtaatc tgtacataat ttataattga ggaaatgaag
    99901 aggtgaagca ttgtgaaaag catattatgt cagataaata aacagccagt taaagctaaa
    99961 tatacatctg atgaattaga atgttttttg gatacaattg agtataatgt aggtgataaa
   100021 atattgcttg ttggtcatat aggaaaccta ggcaagagat tgagaggtct tggaacttct
   100081 gtaactatac tggagaatag taattatgaa gatgtctgtt attctctagt gtataatgaa
   100141 aattgcaatg tagttaaagg taagttagag tttctaccat ttgatgataa tcagttcaac
   100201 aagataataa tagttgacca atttaatgtt attacagatt gtgaaaaagc ttcatctgaa
   100261 atacaaagag tgttaaaggg caatggagag gttatattag aggatttaaa tttaaagaat
   100321 ttaaaagtta agttaaatta tcttaaacat aaattttgtg gttctgttgc aaagattcac
   100381 tatccacatg aagtatttaa tatattttca agattaaact ttgatggtat gattaaagag
   100441 tcaaataaat taaaatatat ttatgtggga aaaagaagat aaatgagtta aaatataaat
   100501 atggatataa tataaaagac taggttaagc ctagtctttt gttataagga gatgtttaga
   100561 tggaaataaa ttatgagtta ataataattg ttatgctctt tgtaatcctg atgtcaatcc
   100621 aatttacttt aaataagata tacttgattc ttaaagaaat aagacaaata cttatgttaa
   100681 agaaaaataa ggaatgatgg ttatgatagg tttagaatat ataaaatctg atattcaaaa
   100741 tatagctgaa gctatagtat cagtactcaa tatagatgta actatagtaa ataaggagtt
   100801 atttaggatt gcaggtacag gagtatatat agacaaaata ggtgagaaag tagataaata
   100861 tacggctttt aaaaaatcac ttacagaaca gatcacaata ctaattgatg acccaaagag
   100921 tagtgatgta tgtagggaat gctataaaag tggggcttgt gtagagtttg cagaggtgtg
   100981 ttgtcctatt atatgtgatg gcgattctca tggcgttata ggccttatag cctttacaaa
   101041 agaacaagca caaattatag aaaataataa aagtggtctt ataaactttt taggcaaaat
   101101 ggcagactta atatctaata aattaaaagc acaaattaaa acttatgagc ttgaattaga
   101161 aaagaaaaaa ttagagacac tattaaacaa tatggacaaa gctgttgtgt ctattgatgt
   101221 ggatggaaaa attgataaat ataattcaaa atttaaagag cttttcaata taaaggatag
   101281 tataactggc aaaaacatat ttgtcgaatt agattttata aagaaacctt ctataaataa
   101341 ctttaagaaa gacaaatcgt gtagtttttt ttataaaaga tacggatatg attcgaaggg
   101401 aatatacaac atcaataaaa tagtattaaa aaatgagtta aagggatatg ttattgattt
   101461 tatagataaa agagatgcta taaaaaacta caataagatg aataaagatt atagaataaa
   101521 attggaaaac ataattggag aaagtgtagc tataagaaat tctaaaaagg aagccctaat
   101581 agcttctaaa tcaacatcaa cagtacttat tactggggaa agtggaacgg gtaaggagct
   101641 atttgcaaga gccatacaca accatagcaa tagagtagat aatcctttta tagctgtaaa
   101701 ctgtgctgct ataccagaca atttattaga gagtgaatta tttggatatg aagagggagc
   101761 ttttactgga gctaaaaaag gtggaaagct tggaatgttt gaagtagctc ataagggaag
   101821 tatattttta gatgaaatag gagatatgag tttgcattta cagtcaaagt tattgagagt
   101881 attacaagaa aaggaactta ataaaattgg aagtaaatca aatgtctcaa tagatgtaag
   101941 aattattgct gctacaaata aagatttaga aaaaatggtt caaaatggca cttttagaga
   102001 agatttatat tatagattaa atgttatacc tataaaatta ccaagtttaa gagagagaaa
   102061 agaagatatc ccacttataa tcaagcatat ggttaaagag tattcaaaaa aattagataa
   102121 aaatgttatt gacatagata gcagggttgt tgatgctatg atggaatata agtggccagg
   102181 gaatataaga gagttgcaga atattattga atatagtgtg aatatgtctt cttcttcaat
   102241 aatcacaatg aatgtaattc ctcaaaaaat taagaatacc tctgtagaag agttagaagt
   102301 taaaagcgat aggataattc cacttgatga actagagaag attgagataa taaaagcttt
   102361 aaataagtac aaagattata aaaaagataa agaattaaca gctaaagcac ttggaatatc
   102421 aagagctaca ttatatagaa aaattgaaaa atacaatata atttcatagt aatataataa
   102481 aaagctatat aaaatttaaa tttttctaaa ttcataactt taaagaaagc tttaaactta
   102541 tactataagt gttttgcata atcttttttt atgaattaaa aaatggtttt tataagttaa
   102601 aaaataacac atttgagccg tctcaaaatg atatagaatc tcattctgag actttttttt
   102661 gtctttttgc gaaattgtca tatgtttctc cattttaaag aatataaata ctctatgtaa
   102721 ataaaaaaaa tacataaata gaagcagtca taccaatggt tatagaatat aagactaaaa
   102781 atataaaaag atataaaaaa tatggcatgt attttgctat aaatatagat aagaaattat
   102841 ttaattaatt atttgagtac taaatctaaa cttaattggg aggtttatat ataatgagag
   102901 atataagaaa agaattagtg gaaatgttaa aggcagaagt taaaccagca gtagggtgta
   102961 ctgaaccagt agccttagct ctagcatgtg caaaggcaaa ggaattatta ggagaagaaa
   103021 tagttgaaaa tcgtatgtta gttagtccta gtatctacaa aaatggcatg tgcgtaggta
   103081 taccaggtac tgaaagatta ggattaaaaa ttgcagcagc tctaggtata gtaggtggcc
   103141 attctgaaaa tggattaagt gtgttagaaa ctctaacaaa agaagaagtt aaaatagctg
   103201 aggattatat ggataatact ccactatcaa taacacctgc tgatacaaga gagaaagtat
   103261 ttatagaagt tgtgttaaaa ggaaaaaatc atattgctaa agtgagaata agaactaaac
   103321 atgataattt tacgttctta gaaaaagatg gagaagtatt attagacaat gaaccaaaag
   103381 tatcagcttc aaatgatgcg gcagaaaaag ctgaaagttt aatggataca gtaactatac
   103441 aagaattaat aaaaaatgta gaagaaattg attttaaaga tatagaattt ttactagatg
   103501 gagtaaaaat gaatgaagag atggctgaat atggattaaa acaaaaaact ggtattggtg
   103561 tcggatatgg aattaaaaag tctatagaag aaggtctttt aggtaatgat gttataaatt
   103621 atgcaatgat gttaactgct ggagcttcag atgcaagaat ggcaggcgta aaaatgcctg
   103681 ttatgagttc aaatggaagt ggaaatcatg gattaacagc aattcttcca atcgttgctt
   103741 ataataaaaa attcccacaa tctgatgaaa aactagcaaa ggctttagct atatctcatc
   103801 tagtaactgg ttatattaag aactatacag gaagattatc tgctgtgtgt ggatgtggtg
   103861 ttgctgcttc tactggagca actgctggta tctcttggct tatgaatggt actgaaaagc
   103921 aaatagaagg agctatagaa aatatgatag ctgacttaag tggaatgata tgtgacggtg
   103981 cgaaagctgg ttgtgcatta aaattatctt ctgcagcatc tgcagctata caaagtgcta
   104041 taatagctaa gcaagattgt tttgtaccac cactaaatgg tatagttggt tcaagtgttg
   104101 agcaaagtat acaaaactta ggtagagtaa gtgacaaagg tatgtctata acagatgaga
   104161 taatcttaaa tgtaatgaat gatatgaata aagttgacta gtactttata atatgttttg
   104221 tattatgagg tataacaaaa atagcataaa taaatttaat tagtaccctc taataaaata
   104281 tgattatgta taaatttatg tataatagaa aaaacttgtt agtgcaagtt ttttcttttt
   104341 ttgtctaaaa tatatagtat gtaatttagt gtggatatat gaactactta aaatataaga
   104401 tacattgtta ataattgttg aatgaacata aaaactcaat aatattgact aatattgaat
   104461 aagagtattg aaaaagtgag caatctctta taaaattaag aaggattatt acaattggag
   104521 gtctttttat ggatatagaa acaaaaaaat gggaagtatt gtattcagaa gaaaaaatta
   104581 aagataaatt aagggaatta ggagcaatta tagaaaaaga ttataaagat aaaaatctta
   104641 tggtagtttc tctattaaaa ggtagcttta tattttgtgc agacttagtt agaaatataa
   104701 atttaccact tagagttaat tttatgacta catctagtta tggaaacaat gaagaaagta
   104761 ctggaaaggt taaagtggtt tcagatgtga ctactgatat agcaggatat gatgttttgg
   104821 ttgtagacga tattactgat tctgcactta ctatggattt tgtgttaaaa catctaaaag
   104881 ctaaaaatcc tgctagttta aaatgctgtg ttcttttgga taaaccaagc agaagaaaag
   104941 ttgatttagt gccagattat tgtggatttg aaatagaaga taagtttgtg gttggatatg
   105001 ggtttgattt tggtgattat tatagaaatg ttccttatat attcaatgtt actgatgaag
   105061 atagataagc aattatataa ttttgtggat gccttaatat gatttttatt aatcgtgttg
   105121 aggttttttt atttaaaaag taattaaagt agtattaaat taattttatg caatttaatt
   105181 atctattttt tataacataa taaaaaaatt ttaaataatt gatgggaaat gagtttttta
   105241 attgtattaa taattgtaaa agagtactaa taattgtaaa agattttaca aaaaagtaat
   105301 gaaatttaag aatcaaagca tatatgttga tataagcaaa tagatacatt atcacataag
   105361 aaattgtcga ttcatataat tatatagagt aatactcaat atttatagag taatactcta
   105421 actttaaaaa aggaggatta attatatgag tgatatttca ggtccaagtt tatatcaaga
   105481 tgtaggtcca acagggccaa caggtgctac tggtccaaca ggaccgacgg ggcctagagg
   105541 cgcaaccgga gcgaccggag caaatggaat aacaggacca acaggaaata cgggagcaac
   105601 cggggcgaat ggaataacag gaccaacagg aaatatggga gcgactggag caaatggaac
   105661 aacaggttct acaggaccaa caggaaatac aggagcgact ggagcaaatg gaataacagg
   105721 tccaacagga gcaacaggag caacgggagc aaatggagta acaggtgcta caggcccaac
   105781 aggaaataca ggagcaacag gtccaaccgg aagtatagga gcaacgggag caaatggagt
   105841 aacaggtgcc acaggtccaa taggagcaac aggtccaacc ggagcagtag gagcaacagg
   105901 tccagatggt ttggtaggtc caacagg
//
LOCUS       DAEQJM010000003       103572 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.003, whole genome shotgun sequence.
ACCESSION   DAEQJM010000003 DAEQJM010000000
VERSION     DAEQJM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 103572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 103572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..103572
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.003"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(1..2081)
                     /locus_tag="KRQ43_000241"
                     /pseudo
     CDS             complement(1..2081)
                     /locus_tag="KRQ43_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
     gene            complement(2076..3725)
                     /locus_tag="KRQ43_000242"
                     /pseudo
     CDS             complement(2076..3725)
                     /locus_tag="KRQ43_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(3826..3978)
                     /locus_tag="KRQ43_000243"
     CDS             complement(3826..3978)
                     /locus_tag="KRQ43_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740622.1"
                     /translation="MDNDWNGLADLIANLITKYAGVLDLENLPNPTPVKNTEDKNKFD
                     IAKSTD"
     gene            complement(4467..4877)
                     /locus_tag="KRQ43_000244"
     CDS             complement(4467..4877)
                     /locus_tag="KRQ43_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2740623.1"
                     /translation="MAKEYYLYIRGQKVKVSEDIYIVYWREKEHEKYLEQVDRKNHLL
                     FFSALDHDGHFTDNIVDESVDVEKIVETQMMIEAVRSAITRLNAEERDIIERLYFNDE
                     TVRSVAKLKSITHPALIKRRNKILEKLKKFIEEL"
     gene            complement(5401..6720)
                     /locus_tag="KRQ43_000245"
     CDS             complement(5401..6720)
                     /locus_tag="KRQ43_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2740624.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLVFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLELYSKSSEIKAFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKTRLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKALQDEEFFIFKIKIFS"
     gene            complement(6717..7370)
                     /locus_tag="KRQ43_000246"
     CDS             complement(6717..7370)
                     /locus_tag="KRQ43_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740625.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYNDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            complement(7468..8844)
                     /locus_tag="KRQ43_000247"
     CDS             complement(7468..8844)
                     /locus_tag="KRQ43_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2740626.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKIFQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSSKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDVHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFVGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIARQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFIIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(8844..9500)
                     /locus_tag="KRQ43_000248"
     CDS             complement(8844..9500)
                     /locus_tag="KRQ43_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2740627.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQKKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(9510..10787)
                     /locus_tag="KRQ43_000249"
     CDS             complement(9510..10787)
                     /locus_tag="KRQ43_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2740628.1"
                     /translation="MIKNAIAYITRKRNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIGENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNKSENNKIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKHIIKIMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMLNITTLGQ
                     SYLILISIIVLSVVFASSLILIKKPKEILSKIS"
     gene            complement(10806..11696)
                     /locus_tag="KRQ43_000250"
     CDS             complement(10806..11696)
                     /locus_tag="KRQ43_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2740629.1"
                     /translation="MDRIKNIINGSTKKDKYKIRDRFRHLFQSVWFLITNSYFEGFKT
                     GKIYGGNLKKICVPGMNCYSCPGAKGSCPIGSLQAVIGNSKYKISYYIVGILFFIGAL
                     VGRFVCGWLCPFGLIQDLLHKIPFFKKVETFKFDKHLRKLKYIILLVFVIILPLFLVD
                     ILGQGSPYFCKLICPIGMLEGGLPLVLLNKSMRNAIGFLYYWKGIILIVTLLLSIIIY
                     RPFCKYICPLGAIYSIFNPISIFRYRLDKDKCINCGKCKKVCQMNIDPVENCNHLECI
                     RCGRCKNACPVDAISYGVRK"
     gene            complement(11863..13020)
                     /locus_tag="KRQ43_000251"
     CDS             complement(11863..13020)
                     /locus_tag="KRQ43_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBH2740630.1"
                     /translation="MKKIVSRGACLLLTLCLSLSTVGCKKSNESNKIKEGQSISSEEA
                     GMSTNEKDKNETFKPSDYTLKTKKEYVYEYLGLKFKLSDKFKKYMDDKKIAMLDDQSP
                     IDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELERIGTIGIFEKNTSEEKISK
                     ITKCDTHTKIGVSSDGKYDCYLSTNSGAESNLLDELKRTEIQIIDKKERPKNGFVLSE
                     KTDLENTEAFNKESVKDLRKLSTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEI
                     PDLVEVQNEMKSKGVNIVGVVTDTVDDNGENKEAIEKSKLIHEKTKASYPFLMPDKTN
                     FNGRLNGIQAMPETFFVDSNGNIVGDTYSGAKSSKEWKQVIEKELEKIKNK"
     gene            13354..13704
                     /gene="mobC"
                     /locus_tag="KRQ43_000252"
     CDS             13354..13704
                     /gene="mobC"
                     /locus_tag="KRQ43_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBH2740631.1"
                     /translation="MANRIRNERLEIKLTEEEKALFEEKRKLARCRNMSHFIRKCVLE
                     KEIYQVDLEPFRDLQGLLSNATSNINQIAKRVNSTGIIYKDDINDMKKQIEYFSKELW
                     QIHSLLLNRTSGGD"
     gene            13710..15041
                     /locus_tag="KRQ43_000253"
     CDS             13710..15041
                     /locus_tag="KRQ43_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBH2740632.1"
                     /translation="MAITKIHPIKSTLNLAISYIVNGKKTDEQILVSTHKCHQETAHT
                     QFLRTRNDVGTNGTVLARHLIQSFLPGEASPKMAHQIGLELCKKILKDEYEFVLSTHI
                     DKGHIHNHIIFNNVNMVTGKCYQSNKKSYHKIRYQSDKLCKENNLSVIDEFYESYKRK
                     YKTNGKSWYENEQSKRGTSWKSRLQFDIDRLIKQSKYWEEFLKKMAELGYEIKYGKHI
                     AFKPKDKTRFTRAKTIGEDYTEERLKERITENQSITTPPVKRRIGNIINMNANAKVKE
                     SKGYEYWATKHNLNTMAESVIFIREHGINSIKQLDKYIQKSAEERQDLQDKMKEIDKD
                     MQLLSDTMEQVHTVKKYRAYYKEYKANPSDKAFFEEHKAEITHYEIALSKLKKSYSKL
                     PNSKDILDKLNKLQEKKNTLIQEYSSTKSTMDELYQIRKNYGIYMGKEMER"
     gene            complement(15077..15883)
                     /locus_tag="KRQ43_000254"
     CDS             complement(15077..15883)
                     /locus_tag="KRQ43_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009354872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PQQ-like beta-propeller repeat protein"
                     /protein_id="HBH2740633.1"
                     /translation="MEISKKELRKISRKFRILASNVMNSYYGEQNANLEEMINYIEQT
                     LLIKEYLHSLEYDVDGLDDLLNTISNSYGRKVLNLGNDSNKRTYLLYRAFSFITGNNL
                     PTYTFGWYYAGSNKYQDMAKAFGDRMVYPFVLEVENYMKDISTDMGYDENNALYNINV
                     NSSGVQVNIAEHGSTINADQENKFNTEEVIKAINNVEDLIKGMEDDNSKSILNQNLDN
                     IKNEIKQKHPKKEVLTTCLKSMHFITTSVALIPDLALGIKMLASLIGISI"
     gene            complement(15873..16334)
                     /locus_tag="KRQ43_000255"
     CDS             complement(15873..16334)
                     /locus_tag="KRQ43_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBH2740634.1"
                     /translation="MANDIKFEISVPADEEGYVQLKCPSCSEKFMLTVEDIEAESTID
                     IWCPNCGLTHENYLDDDIYELAERIVENQVAEMLNDFSKNLEKSFRNSKSIKFKRGKE
                     IKKEAELPIGRKTGDYEEKKYLCCGKTARISSIKKLEGSYCPFCGEMIDGD"
     gene            complement(16362..17429)
                     /locus_tag="KRQ43_000256"
     CDS             complement(16362..17429)
                     /locus_tag="KRQ43_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009354804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBH2740635.1"
                     /translation="MSGKLYIAAAGSGKTRKIIEDSLNTHKKILILTYTITNEQQIIS
                     RIKNKVGVIPNNITVSTWFSFLLKDGIRPYQGSRFKERIEGIIFVNGQNNTYVKKTSN
                     KYFAKDNRVYTDKLSECVVELNDKCNGKVFERISGMYDCIYVDEVQDMVGYDLEILKC
                     LIASRIEVIMVGDPRQCTYSTHSSKKYKKYSCGKIDEFLKNECRKLDVRIDETTLNCT
                     YRNNDIICKFANSLYPERTSTNFVRRAEDESDGVMIIDKADVEKYLQKFNAMQLRENK
                     RTSVNNEYPYYNFGESKGLEFQRVLIYPTQPMWDWIINNNTSLKEQSKARLYVAVTRA
                     ENSVVIVRKDARPCSLPVVKL"
     gene            complement(17426..19048)
                     /locus_tag="KRQ43_000257"
     CDS             complement(17426..19048)
                     /locus_tag="KRQ43_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2740636.1"
                     /translation="MSIRKLKIKNFKCFSDWFIVDFENGINILVGNNGTGKSTILEAI
                     NLVLTGTYHGKNIRNELTQYLFNKNIVENYIREVNEGVNVEPPKIIIEAYFDAEMPSF
                     LGDGNSEKTKDTPGICLSISFDEKYSNEYKMLCKNKITSLPIEYYEVSWMSFARENIT
                     ARSIPIKSAMIDTTSYTPTSGSDIYISRIVKNLLDDNEIINISQAHRLMKEQFSRDEN
                     IANINRKLTETSNNELTISVDFGTKTSWESSLVTQLNEIPYNNIGKGTQCIVKTQLAL
                     SDHKIENKQIVLLEEPECHLSYSNLNILLDKVNESVKEKQIIVTTHSSFVSNKLGLEN
                     LILLNRGKTLRLGDLSNETNLFFKRIAGYDTLRLLLSNKAILVEGDSDELIVQRAYMD
                     SHNGKLPINDGIDIISVGISFLRFLEIAKLLELRVSVITDNDGNIDALNRKYSDYLGD
                     NCCENINIYFDDSTHEYNGSLENYNYNTLEPCIYRSNSMSILNEILNKSYEDPDDLLK
                     YMKGHKTEVALKIFESDKAIEFPQYIKEGILI"
     gene            complement(19251..19481)
                     /locus_tag="KRQ43_000258"
     CDS             complement(19251..19481)
                     /locus_tag="KRQ43_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740637.1"
                     /translation="MRVFSYKRLFKKLIDLDMTNNELMEKAKVSKSTFYKMKNGQNVT
                     TDVLLRICNALDCDIEDIMECVIIEDVRRMGV"
     gene            complement(19621..20280)
                     /locus_tag="KRQ43_000259"
     CDS             complement(19621..20280)
                     /locus_tag="KRQ43_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH2740638.1"
                     /translation="MDYKTMRDRVEDMLSDNHKDFVKAIISMEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLRGQGQIKDLLYVREEKDNLINIVGNIVGEVDVIEREN
                     KNGETFKVANFSVVSKDDEGNKLYHNCSVYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNIRILSSKLLKAKEQMKGQEEKKESILGAIKKYQAEDKEKPKEKKEASKEAE
                     R"
     gene            complement(20323..29052)
                     /locus_tag="KRQ43_000260"
     CDS             complement(20323..29052)
                     /locus_tag="KRQ43_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH2740639.1"
                     /translation="MRINDFHNILELIKQDVLYNEAEYLKLLKVVGNNQRYDFRSQLS
                     IYDKNPEATACAKFDYWRERFNRTVMRGQKGIPILEDYGTYKKVDYIFDISQTVSKNR
                     DVNEVNLWRFDKEAHQDVLKEMIKSEGYEESESTLENIFSLSRLYGDEKIDTLMNELR
                     VADEDRISFTKFVRDSVSYAVASRFKLDYPMDYELLRENFQRFDSISLMSLGESVSDI
                     SGKIIDETIQKSKELELQKEVLIGKEAGYNKIKEELEEVEENVFRRDDQERNENERVL
                     RNGEYGRDNRKNQGEYAKQLGGTDGLYKEVSESDLRSDEAELPFTERGAEPLRDAFGS
                     IQGEEADRTPDGYSETGSRVYESREAKVDSSLEDRGREQSAVWGDDFSSQRNDHQGSS
                     GDLKDNTDKGIIEAEKASFSLPENSYGQISLTIPLTEKDIDTVLINGGNHDGGRLPVI
                     AEFSKGKSIEELGEYLKDTFKGGNGFYIDEREVSSWYSDKGIHLAYGTSAREDNTQIL
                     SWSDAASRINELLDRGEFATNVELLEAQDYERDRISESLWYLTHDLSEEGIEQGYFNS
                     FERGGGFPQETKRLSEALKNPEYLKETIKEYSRFLEGYKESRNVLRYHYHKVDSLYQK
                     LQELELQRKEYSTNLTELPKVKLFITEDEVLESLSRGSGVDRGKERITKFFKENHTLQ
                     EKANFLKDEYGIGGHSHVVSGAMGSDEWHDAKGFKLQKNDCNDVFLTWTSVAKHIDEL
                     LSKKLYFEEKETESTAEIEEVKEPQYYSKNDPGNLMPDEILERVPEIYAQEDVDLADK
                     QVHAAYIIPFRSNWTWYMTEYDRESGDAFGLVLGIEPEWGYFNLEELKELNAQRLILE
                     DFPKTFRELKDIELIKQMDEQELQFVFNGELSFEDKVELEAPEETEEATKRGTVQATL
                     FDYLKEREEVELNEKEDSLLEEFAVKAGDTVYFNHEEYKVREISKNEITGRYDLWLDP
                     VRSGNHQIPIVDFTDNEDLLNKISLERPNFIVGDEVKYKDKNHTITRFDDMRKNLNTV
                     TVKDNTEYFGGMITSFDVIPYRLESDLERVFENLTYKQPEQTTEETQIRKAEAHNFKI
                     TEETLPEKLSPSERLNNNLEAISMLNRVESGQRELDSTAQEVLARYVGWGGLSEVFDE
                     SKEGQWKEARAFLNENLSHAEYEAARESTLTSFYTPKTVIDGIYKTLSDMGFKQGNIL
                     EPSMGIGNFIGNIPDEMNKSKFYGIELDSVSGRIGKLLYPESEVQIKGLEETSFSNNF
                     FDAVIGNIPFGEYKVNDREYNKNNFLIHDYFFAKSIDKVRNGGIIAFITSSGTMDKKD
                     ESVRRYLAARAEFLGAIRLPNDTFKGIAGTEVTSDIIFLKKRDSIRERDEDWIHLAED
                     ENGLTYNKYFVDHPEQVLGTMREVSGRFGNTLACLPKENADLKELLTKASEEISKGST
                     YEEIELLDDEITSIPATDDVKNFSYTVIDDEVYYRENSLFIKKEITDKNKEKIKDYLE
                     LNTALKDVIYKQKEDYSDDEVKKAQEKLNEVYDNFSKKHGFINNLSNTRALKEDSNFP
                     LVSSIEILDEEENVKAKGDIFSKRTITKAKVIDHVDTSLEALVLSVSEKGYVDFEYME
                     SLTGKDRPTLIEELRGEIYLNIREEQNFYRPLSFNLEDGDLPFACANGSNSYKYGYVT
                     KDEYLSGNIRDKIAIVDSYLAKLRQTERELPHLGFVENGKEKELISYEMNRLEYQKAE
                     LTKVLPKELEASEINVRLGATWIPIKDIEKFIFETLKTPGYARWDIKVKFSNITSEWN
                     VEGKSRDKGNDLAEMTFGTSRVNAYKLIEDALNLKETKVFDQIINPDGSKTSVLNKKE
                     TMLAGQKQELLKEEFKNWIFNDQERRNRLVKLYNERFNSIRNREYDGSNLSFEGMNTE
                     IDLRPHQRNAIARSLYGGNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPNHL
                     TGQIGREFMQLYPSANIMVADKKDFEPKNRKRFIGKIATGEYDAVVIGHTQFEKIPMS
                     KEYQEKHIQDQINEIVNYVEEYKHDRNQNFTVKQLEKTKKKLETRLEKLNDDFKKDDV
                     ITFEELGVDMLFVDEAHNYKNLYLYTKMRNVAGIGQSEAFKSSDMFMKCRYMDEMTGG
                     KGIVFATGTPVSNSMTELYTMQRYLQYESLKKNHLEHFDSWASTFGETQSSFELSPEG
                     TGYRVKTRFSKFYNLPELMSMFKEVADIQTADMLNLPTPEANYEVIKTEPSEEQKEIL
                     KSLSERADDVRNRVVEPDVDNMLKITNDGKKLALDQRLINPLLPDNPDSKVNVCVKNV
                     FAIWDKTKENRSTQLLFSDMSTPKGDGEFNIYDDIREKLVAMGIPKEEIAFIHEANSD
                     KQKDELFAKVRKGEVRILMGSTQKMGAGTNVQNKLIALHDLDVPWRPADLEQRAGRIV
                     RQGNENEKVNIYRYVTENTFDAYLWQTIENKQKFISQIMTSKTPVRVAEDVDESSLNY
                     AEIKALATGDPKIKEKMDLDNEVTKLKMLEANYKSNRYRLEDKVAKNYPEEIARTEKL
                     IEAVKKDISNVEPKAEGEEKFTSITIAGEKITDKKLAGERLLEAISKVKINESKVIGK
                     YRNMDLEVSYNFFTNSHNFSLNGVAKHLGELGTSADGNITRLDNALEKMPEKLNMLEE
                     KLISTKEQLENAKEELKKPFEKADELKTKVLRLAELNKLLDMGEVEEKKNDNPLVEDV
                     KRAIIDFCNREYEENHSYDEFHTLYPDLKHIGIAYTNTPDERHGIQYELNLEEKTWTQ
                     YIDDTPIKTESFDYENKGENEALRNMKNEIELSTFSDLVYVDSEDLRVATGLDIDDEG
                     NFYDPFAKDLDNDGIPDRYDSDFKDSDYFESTYDVEDNLHSKEETTQKSDDKPSILGQ
                     IRAYQEESKTEEKQKIKEQEFLR"
     gene            complement(29135..29938)
                     /locus_tag="KRQ43_000261"
     CDS             complement(29135..29938)
                     /locus_tag="KRQ43_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HBH2740640.1"
                     /translation="MSKINVEGSEISIIAIDNRDYISLTDMVRNIENGSALIEKWLRN
                     KNTIEFLGIWEEMYNTNFNSPEFEGIKNEAGFNRFILSVKQWVEKTNSIGIVARAGRY
                     GGTYAHKDIAFEFASWVSPYFKLYLIKEFERLKEEEQKKLGWDIKRNLAKINYRIHTD
                     AIKNKLVPDKLSKEKINFIYASEADILNVSLFGITAKEWRDENPDLKGNIRDYADISQ
                     LVCLSNLENLNAVFINEGMSQSERLEKLNAIAIEQMKILSESESIKKLK"
     gene            complement(30023..31729)
                     /locus_tag="KRQ43_000262"
     CDS             complement(30023..31729)
                     /locus_tag="KRQ43_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBH2740641.1"
                     /translation="MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYRVSWCVGHLI
                     QMANPDAYDEKYAKWNMADLPIIPSDYKYEVAKATKKQFNILKKLMNDKEVDTVINAC
                     DAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDNLTDGKDYDNLFESAQA
                     RAIADWLVGMNISRLYSCLYQQNYSVGRVQTPTLAMIVKRDDEIANYQKEKYYTVELS
                     MNGFTLSTDRIDDEVAAEQLISLVGDKIEITDVIQKEKITKPDLPFDLTTLQRECNKY
                     FGYSAKQTLDYTQSLYEKKLITYPRTDSRCLTEDMIVSTVNNILGKNDFDTERIKVVF
                     NSKKVTDHHAIIPTISSVKEDVSELPLSEAKVYFLISDKFHASVGYPLIENTTKIVAS
                     FDGFEFTSSGKVIKDEGFSKYLKEYKSKKSEDAVLPDVSVGDVLSVENKEVKEKFTQP
                     PKHFTEDTLLKSMEIAGNDALEKGVEVERKGLGTPATRAGIIENLIFKRFVERDKKNL
                     IATHKGISLVTIVADTFKSAETTAKWEMELSDIAQGKSSKKEFLDAIENEIKEAVLTY
                     RK"
     gene            complement(31824..33365)
                     /locus_tag="KRQ43_000263"
     CDS             complement(31824..33365)
                     /locus_tag="KRQ43_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBH2740642.1"
                     /translation="MKTSLKKNNKFWTVALAVIVSISCILGLWTVVYAQEQKSEAPTK
                     NEAVQTEVEVNVRYIFEDEKVFKEEKIKAEKGQLIDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGKDEIIRKVAKMEVKDKETQTEEEKPKQDECTQTEDKGTQTELSKDDISKIEKEA
                     KELQDKLDKLNCELKDKDKLSDKQKNKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKKE
                     IDKLTEKVKELEKKATETNKAPVTSQSVTPISPISGIKTSSGISPQTPQTSVSSTGKG
                     SSDSVSSGNTTKDTGKGKTEVKEKEKEVRYPNKLTAKAPANNSQDSSMGSASKSVNTN
                     KGVASSPSKARASVTENKDNANKEYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEVVKEEPVKEEVKPEKKDEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSESESEEEINDADE
                     VEDEE"
     gene            complement(33340..33579)
                     /locus_tag="KRQ43_000264"
     CDS             complement(33340..33579)
                     /locus_tag="KRQ43_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH2740643.1"
                     /translation="MKKELTTVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIAI
                     CRKNNITISDLIAKVNRQKAEMKKEKTNENQFEKE"
     gene            complement(33591..35723)
                     /locus_tag="KRQ43_000265"
     CDS             complement(33591..35723)
                     /locus_tag="KRQ43_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBH2740644.1"
                     /translation="MGKKLKKDFKERHKASLEREMFHSKTDTIPEESKLKHNDDYRGK
                     IVHEKERFQDKVHEKTSKVSADNEKSYGTSKRNEKYRTSDKGDVNSAIETGRSDYITE
                     VKDGKIYDPLGKDLDNDGIIDRYDNDFRDSNYFESTYDVEDNLSHKEKSLENSFKNHK
                     TQKSRYKRKNYSESLYTRKKDDAPKGNKADDKKAGKDAVSGKVYSSLSKDQKKKLKKD
                     MVKVSALSGLAKGSETVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKKYSDKKRAK
                     RGYDLTNKDYKIRKRKSKLEFRDAKKELKKTDEYKRASAYKRFQKKNQVKAAISRENK
                     SRLRDRIKEGLIGTLKSSKDMIIRKAKGLMLIFIGIIILGTFVINFAGTGMTGFMNST
                     SSVLTTSYLSKPNVLSEINQKFSDMEGELQSEVDYVKENYPGYDEYILNNTEYIGHNV
                     HELLSYITSRCGEVKSVSEVESILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNE
                     YTESHEEPYEYKKLIVTLHKKEMDSIIRKVFANYPDNLKHYEALFLAQGNMREAFGNS
                     DLISANGGIGGGKEYEASTEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGG
                     NACDMYRNYTFTSDRSKLKVGMLVAVESSSSGSSAGLTYGHVGIYIGDGKVIDNIGRI
                     RVTTLDDWIATFCKHHPVGFGFPPNVKK"
     gene            complement(35727..38156)
                     /locus_tag="KRQ43_000266"
     CDS             complement(35727..38156)
                     /locus_tag="KRQ43_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2740645.1"
                     /translation="MNKKRKIQQIKLMQNEKALRSQKRDLKKSNCKSKKDKGGILDLI
                     FKKEPKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSISIEFSYINQLGRNEEMKSAIQIPDKKDGFDDIRFEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLEIDILSSLKSMGVRAESLNGEERLKILHD
                     VLNPNKTFKFSYKDLKKRESTKTYIVPDEFNFTPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIRAIDQSEAIKMVKRKNTDIDKMKIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHSQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYEKYFEHPTPDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFIDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(38068..38457)
                     /locus_tag="KRQ43_000267"
     CDS             complement(38068..38457)
                     /locus_tag="KRQ43_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBH2740646.1"
                     /translation="MAYVPIPKDLNRVKTKVAFNLTKRQLIGFTLAGLVGIPVYLFMR
                     KFVPNDIAVIFLIVSTLPIFFITLFEKDGLTFEKYFKYIYLHKFYQPQKRVRKEVYLE
                     QEKKNSANKTHAKRKGIEKSKAGLKEK"
     gene            complement(38461..38721)
                     /locus_tag="KRQ43_000268"
     CDS             complement(38461..38721)
                     /locus_tag="KRQ43_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH2740647.1"
                     /translation="MNKRKTVFIVVIGAGIMAIIDRIRLHNKVEELEEKTEDIGRCHN
                     DFYLIQQRYNKNTDEQLATIQEEIGSVYEHFEELSKGKEDGR"
     gene            complement(38739..39602)
                     /locus_tag="KRQ43_000269"
     CDS             complement(38739..39602)
                     /locus_tag="KRQ43_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740648.1"
                     /translation="MFGIFDKIEEFFKELLLGGIQANLESMFLDINDKVGAVATDVGK
                     TPMGWNGDVFAFIKSINDSVIIPIAGLIITAVLCIELINMVMQKNNMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFEFSMAVFDVAQHMVNKAAGVINTSAVISGDQIVKMVDGLKDKG
                     LGELVMILFETSLIKVAIQVISIVIMLVVYGRMFEIYVYSSISAIPFATMGNKEWGQI
                     GTNYIKGLFAIGLQGLFLMVCLGIYAVLVKTIQITDIHTSTFTILGYAVLLGLMMLKS
                     GTLAKSVLNAH"
     gene            complement(39622..39705)
                     /locus_tag="KRQ43_000270"
                     /pseudo
     CDS             complement(39622..39705)
                     /locus_tag="KRQ43_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(39796..41466)
                     /locus_tag="KRQ43_000271"
     CDS             complement(39796..41466)
                     /locus_tag="KRQ43_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH2740649.1"
                     /translation="MAMMNEMEYRTIGSALAGGYRAAVYCRLSKDDDLQGESASIANQ
                     RDMLEKYCEKQGWEVVAVYQDDGFTGLNMERPDLQRMLRAIERRQINLVITKDLSRLG
                     RNYLQTGHLIEDFFPRNGVRYIAMNDGIDTLRDNNDIAPFKNILNEMYSKDISKKVHS
                     SYLLKAQKGQFTGCLAPFGYRKDPEDKNHLLIDEETAPIVRLIFGYALNGHGPNYIRR
                     RLEEEKIPCPTWWNRERGLRNTRTKWEKKDPEKGRYMWDFSVIKDLLMNPVYTGAIAS
                     QKKDYRFKIGTIGEKKPEDWIVVEGQHEPLIDRMSFDIVQNKLKSRQRPGQTNEISLF
                     AGLIKCGECGKSLTVRYTNAKHPQQIYSCKTYNAFGKNHCTQHRIDYDTLYSHVLRKI
                     RECARAALMDGEAVADRLTNTCEAEQREQREAMERSLTRDEERIEVLDKMVMRLYEDM
                     IAGRISEQNFNTMLEKTQTEQAELKAKVSEGRKRLSDEVQLANDAKQWVEAIQEYANI
                     TELDAATLNRLIKEIVVHERIDEDKTRHISIEIHFNLKPIPEVEQVTA"
     gene            complement(41467..41664)
                     /locus_tag="KRQ43_000272"
     CDS             complement(41467..41664)
                     /locus_tag="KRQ43_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009249737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740650.1"
                     /translation="MAKNKTEIHVTTVFDGELDATDVFVSLISQKYGKTNTKEYLAKK
                     KDLKYNEDEVQKSQIPSGLCG"
     gene            complement(41906..43243)
                     /locus_tag="KRQ43_000273"
     CDS             complement(41906..43243)
                     /locus_tag="KRQ43_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005945226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
                     /protein_id="HBH2740651.1"
                     /translation="MNAMQPPQSIEEIKAGLGTTEKGGVRQSIRNCLTVFQRDPLLSG
                     AIAYNILTDRKDIIKPIGFHRESTALNDTDMKYLLLYLEETYGLTNEKKIDNAIGIVA
                     NENKYHPIRDYLNTLVWDGTERIRFCLRHFLGADADDYTYEALKLFLLGAISRAFQPG
                     CKFEIMLCLVGGQGAGKSTFFRLLAVRDEWFSDDLRKLDDDNVYRKLQGHWIIEMSEM
                     MATANAKSIEEIKSFLSRQKEVYKIPYETHPADRPRQCVFGGTSNALDFLPLDRSGNR
                     RFIPVMVYPEQAEVHILEDEAASRAYIEQMWAEAMEIYRSGRFKLAFSPAMQRYLKEH
                     QRDFMPEDTKAGMIQAYLDKYTGSMVCSKQLYKEALNHAFDEPKQWEIREINEIMNQC
                     ISGWRYFPNPRMFSEYGRQKGWERENPATDLCNPSEKTRDGFVEVSEQMELPF"
     gene            complement(43212..43856)
                     /locus_tag="KRQ43_000274"
     CDS             complement(43212..43856)
                     /locus_tag="KRQ43_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBH2740652.1"
                     /translation="MNVFEAVKQSVTTRQAAEHYGIRVGRNGMACCPFHHDKTPSMKL
                     DRRYHCFGCGADGDVIDFAAALYGLGKKEAAVQLAQDFGLSYEDWKPPGKVKKPKPRQ
                     KSPEEQFQEAKNRCFRILADYLHLLRAWRKDYAPHSPEEAFHPRFVEALQKQDQVEYL
                     LDVLLFGETEEKAALITDYGKDVIQLEKRMAELAAANAARTKKHHERHAAAPEH"
     gene            complement(43922..45502)
                     /locus_tag="KRQ43_000275"
     CDS             complement(43922..45502)
                     /locus_tag="KRQ43_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HBH2740653.1"
                     /translation="MPCPHNEITIVQRSQRQSAVAAAAYQSGEKLFCEYDQQVKHYPE
                     KRGIVHNEILLPANAPPEYADRNTLWNAAEAVEKQWNSQLARRWVLTIPREIPPDQYA
                     VIVREFCEQQFVSKGMIADFAIHDPHPPGHNPHAHVMLTMRAMDEHGKWLPKSRKVYD
                     LDENGERIKLPSGRWKSHKEDTVDWNDQKYCEIWRHEWEVIQNRYLEANDRPERVDLR
                     SYARQGLDIVPTVHEGTAVRQMEKRGIQTNIGNLNRDIRAANRLMKSIRQLIQNLKGW
                     ITELGEKRKELLAQKAAEEATLLPNLLMKYMEIRKEERKDWTRAGQNRGTSQDLKAVS
                     EALSYLRQKGLSTVEDLEVFLESSGKSAADYRNQMKPKETRSKVIDGILASRTDCQEC
                     KPVYEKYQKIFFKKTKEKFKQEHPEVARYEKAAAYLAKHPDDKDSTQKELQEEQETLL
                     EEIAALKTPLTEVQEDLKKLRDIRYWVRKATPGTEESKEPPKKQPIKEVLQDKTDEKK
                     AQRTAPEQTKHKQQDMEL"
     gene            complement(45690..45833)
                     /locus_tag="KRQ43_000276"
     CDS             complement(45690..45833)
                     /locus_tag="KRQ43_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009249958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740654.1"
                     /translation="MKKIGLGIAILLFAIIISLCSSGMGLLVIGIGIVGLIFSIIGFI
                     ERK"
     gene            complement(46133..46429)
                     /locus_tag="KRQ43_000277"
     CDS             complement(46133..46429)
                     /locus_tag="KRQ43_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HBH2740655.1"
                     /translation="MPDTSKLEKLNRELEKSEKKLRKAINDEKVLQHQLKQLTRKERT
                     HRLCTRGGMLESFLQEPERLTDDDVMLLLKLIFHRQDTQELLKKLLERKKPETP"
     gene            complement(46422..46763)
                     /locus_tag="KRQ43_000278"
     CDS             complement(46422..46763)
                     /locus_tag="KRQ43_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009251547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBH2740656.1"
                     /translation="MNFEFMTIDTPLPPCMPFPRALTGFPVSSTAKVMYCRMLDAMLS
                     KGQEDENGILFVCFPVTAIAAVLSRSPMTVKRSLNELETAGLIMRVRQGVGEPNRIYV
                     LIPGKEDAALA"
     gene            complement(46760..46948)
                     /locus_tag="KRQ43_000279"
     CDS             complement(46760..46948)
                     /locus_tag="KRQ43_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740657.1"
                     /translation="MPRMSKKRKYELSFYLNDRGRVTYNELCRKCQHGCRQSFRAVVI
                     DCPRYLSKRAKKKEAHTE"
     gene            47432..48238
                     /locus_tag="KRQ43_000280"
     CDS             47432..48238
                     /locus_tag="KRQ43_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740658.1"
                     /translation="MKGATSIQERLWELRKDKGLNLEELSKLTGISKSALGSYEKEDF
                     KEINHGNLITLADFYGVSVDYLLCRTENREQINTSLTELHLNDEMVALLKSGRINNRL
                     LCELATHKDFIKFLADIEIYVDGIATMQIQNLNALVDTVRHEIIERYRPGEDDPHLKV
                     LQAAHISDDEYFSHMVLDDLNLIIRDIRETHKKDSESAPQTTVADELKENLEAVENFK
                     GSRDEKLVILYCKQLGINYKNLSEEEFRWLIRILKKSKKMGTPISQRKKR"
     gene            complement(48332..49633)
                     /locus_tag="KRQ43_000281"
     CDS             complement(48332..49633)
                     /locus_tag="KRQ43_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter MatE"
                     /protein_id="HBH2740659.1"
                     /translation="MNNKRTFFQYVIPSVLSFALSGVYAIVDGFFVGNSIGDAGLSAI
                     NIAYPITAVLQSVGTGIGMGGSVKYSILKAAGNEKKAREFVAGATWLMLLFSAVLTVT
                     VFFTSEKILSALGASGELLTLGNEYIKVIALGAILQVFGTGLVPFMRNYGGSLWAMIA
                     MICGFATNIALDYTFVWVLGRGMYGAALATIIGQGVTMAVALVYCAIKKNLTLKIAPV
                     DTPKTAFQILKIGLAPFGLTLAPNISLVIINRFSVYYGGQEAIATYACISYIICIVYL
                     LLQGVGDGSQPLMSQFYGAGEEKSLKQTKTLAYEFSMVLAVISAILIYLLRGKIGLLF
                     GSSAEVNAGVIKVMPIFLVSVPFDAITRVSAAAFYATEKSVLSYVLTFIEPIIMLVLM
                     LMLPPVFGGQITIWWSAVFAKVITASVSIVLSVRYSAQRNR"
     gene            complement(49626..50060)
                     /locus_tag="KRQ43_000282"
     CDS             complement(49626..50060)
                     /locus_tag="KRQ43_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2740660.1"
                     /translation="MENNHFNVAWAKSTALYTKAASVLGIGYPEMMVLYALESMGELT
                     QKQIAENFGMQKQTVHTVVSALQKKGYLLLEASEGDKREKRIVLTESGQVYAHRMIAP
                     LRKAEEKVYRTIGNERLQAMCEILDLFNLLFERELRGGLGSE"
     gene            complement(50177..50554)
                     /locus_tag="KRQ43_000283"
     CDS             complement(50177..50554)
                     /locus_tag="KRQ43_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015537038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HBH2740661.1"
                     /translation="MSELKPRITENGIDYILVGDYYIPDLKLPEEHRPIGKYGRMHRE
                     YLREVHPAKLNTLTLTGELWTYLADLNEQAQERLDTIMEQMKDAEGVTEELKRTQQME
                     WVRRCNNIHNRAEEIILQEMIYS"
     gene            complement(50514..50786)
                     /locus_tag="KRQ43_000284"
     CDS             complement(50514..50786)
                     /locus_tag="KRQ43_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2740662.1"
                     /translation="MHISYKPLWHTLLERDMRKEDLRLAAGMTTNMIANMSKEGKHIS
                     MDTLARICETLNCEITDVIELVSDEPASTGGKEHERIETKNNGKRN"
     gene            complement(50942..51100)
                     /locus_tag="KRQ43_000285"
     CDS             complement(50942..51100)
                     /locus_tag="KRQ43_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740663.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQFMAN"
     gene            complement(51104..51415)
                     /locus_tag="KRQ43_000286"
     CDS             complement(51104..51415)
                     /locus_tag="KRQ43_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH2740664.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGEEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKAEKAEDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(51579..51812)
                     /locus_tag="KRQ43_000287"
                     /pseudo
     CDS             complement(51579..51812)
                     /locus_tag="KRQ43_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565771.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraG"
     gene            51954..52127
                     /locus_tag="KRQ43_000288"
     CDS             51954..52127
                     /locus_tag="KRQ43_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2740665.1"
                     /translation="MDYMTLKEASEKWGVSSRQINYYCTDGRIPGAVKMAGVWLIPKE
                     AEKPKDRRYNESR"
     gene            52132..52842
                     /locus_tag="KRQ43_000289"
     CDS             52132..52842
                     /locus_tag="KRQ43_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740666.1"
                     /translation="MLHIAICDDEKDFVQYLTDLLNQYSKETGRDIKITPYYDGMELI
                     EKYDPTIDLIFLDIQMKVVDGLHAAERIRQMDETVGIIFLTTLTQYGLEGYKYHATNY
                     IIKPMKYARLKSEMDKFLERSQKEDTPSLVITNDTGKYKVPLKSIRYVETYNRNLMFH
                     TEQENIICYKSMKEVERELCDKDFVRCHTSYIVNLFYVKGIKKLDIELITGEIIPISQ
                     PKRKEFMERLTDYWGDML"
     gene            complement(53113..53274)
                     /locus_tag="KRQ43_000290"
                     /pseudo
     CDS             complement(53113..53274)
                     /locus_tag="KRQ43_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569186.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            53885..54070
                     /locus_tag="KRQ43_000291"
     CDS             53885..54070
                     /locus_tag="KRQ43_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH2740667.1"
                     /translation="MLKKYWIKCPICNGKTRVQVFHNTVLKDFPLFCPKCKLTHIIDV
                     EKLEIVIKNTEKQTFII"
     gene            54087..55070
                     /locus_tag="KRQ43_000292"
     CDS             54087..55070
                     /locus_tag="KRQ43_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBH2740668.1"
                     /translation="MKRLPKYTPAEVRNDPYGFTYKEMSEVIGENEAKALYEELYKQL
                     PRKKNLSMLVKNICKSSDTEKYVYELKDNKYIETVFIKRRDGGTVCVSTQVGCPVGCI
                     FCESGRNGFVRNLTSSEIVQQIILLRRKVNRIVFMGMGEPLFNYDNLIKAIHILRDRY
                     GLNFPTDGITISTVGPVDQLKKLREEHLKIQLTISLHAATQSARNRIIPHMRIYAIED
                     VVKQALSYSERHNRKIVFAYLLLPGINDRPSDVRQLAKWFRGKKVMINVLQYNPTSNS
                     RIKAPQKREIVAFKHQLEQAGLEVTMRVSHGREINAACGQLANTYNKFKKK"
     gene            55544..55981
                     /locus_tag="KRQ43_000293"
     CDS             55544..55981
                     /locus_tag="KRQ43_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2740669.1"
                     /translation="MELSSSDKERIQHQYDALAKKTLVGEAKSHRRTLAKRAAREVTF
                     SDLSESELAQLFTTDEYESDYFRFQVSGFDVLVKNELLAEALNALPERKRDIILLSYF
                     LDMSDAEIGELLNVVRTTVFRHRKSALAKIKQYLEGKADDEYR"
     gene            55965..56207
                     /locus_tag="KRQ43_000294"
     CDS             55965..56207
                     /locus_tag="KRQ43_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2740670.1"
                     /translation="MMNTVRKSENLLPFPVISAAANGDTTAMCAILKHYEGYIAKLCT
                     RTLKDDAGNTYSYVDEEMRNRLQVRLITRTLAFHVG"
     gene            56666..56839
                     /locus_tag="KRQ43_000295"
     CDS             56666..56839
                     /locus_tag="KRQ43_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HBH2740671.1"
                     /translation="MDKKQTITTERKIGKITYLVQALPSEKATDTIHKKIEKLIVKDL
                     QKKPGNPGFLASE"
     gene            56917..58590
                     /locus_tag="KRQ43_000296"
     CDS             56917..58590
                     /locus_tag="KRQ43_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016289898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH2740672.1"
                     /translation="MLQSNKITALYCRLSQEDMQAGESGSIQHQKMILQRYADEHHFL
                     NTKFFVDDGFSGVSFEREGLQAMLQEVEAGRVATVITKDLSRLGRNYLKTGELIEIVF
                     PENGVRYIAINDGVDTAREDNEFTPLRNWFNEFYARDTSKKIRAVKQAQAQKGERVNG
                     EYPYGYIPDPNNRHHLIPDPETAPIVKQVFAMFVSGVRMCEIQKWLAENKVLTIGALR
                     YQRTGQARYQRAMIAPYTWPDKTLYDILARQEYLGHTITAKTHKVSYKSKKTRKNEEE
                     QRYFFPNTHEPLVDEETFELAQKRIATRHRPTKAAEIDIFSGLLFCAGCRHKMYYQQG
                     VNIEPRKFSYSCGAWRNRARTGSECTSHYIRKNVLLDLVLEDMRRVLRYVKEHEQDFI
                     CKATEYGDMEARKALAQQQKELFKAQARMTELDTLFRKLYEDNALGRLTDERFVFLTS
                     GYVDEKKSLAARIDELQQQIATVTERKRDISRFIQIVGKYSDIQELTYENVHEFIDRI
                     LIHELDRETNTRKIEIHYSFVGQVDTEQEPTQVVNHDRRNMVDVKSIAI"
     gene            58614..59069
                     /locus_tag="KRQ43_000297"
     CDS             58614..59069
                     /locus_tag="KRQ43_000297"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740673.1"
                     /translation="MKEYTLIIKGEMDFIILSPQVLSSLITQIHNSPERKVVVSIESI
                     MPPKFTDYLLRVINSNRFSNERFRYRYILENPVTKKGMYEILRQQLSRTNTERFPCFQ
                     TIQLTDTFQGNVELDMECNDLFFWACKDTAAKFVYTFPDGREETLVIEY"
     gene            complement(59117..60769)
                     /locus_tag="KRQ43_000298"
     CDS             complement(59117..60769)
                     /locus_tag="KRQ43_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008978103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH2740674.1"
                     /translation="MSRKKQVYEKITALYCRISLDDGGDNESMSISNQKLMLRDFAEK
                     HGMFQYEYYVDDGYTGRNFNRPSFQRMIADIEAGKIGCVITKDLSRLGRNYIEAGSYI
                     EIFFPKHNVRYIAVTDGVDSLTRQEMDITPFKNILNDMYSRDISKKVLAGRMTRSRQG
                     KFCGGQPPLGLMRDPEDKGHLILDPETAPVIRKIYDMALDGWGCMRIAKQLMDDKIPI
                     TRVKSNTECDVNYYSWGSARISHILRNPFYKGAHLVCRTHQKGIRSNTYDIIPREDWE
                     VIEGCHEAIVTPEEWEQVQDIIDRRPTIMKGNACPFYNLFHGLVYCATCGKSMQVRYE
                     KVGRTGKNRFTGEMREPIDRAYYICQTYNRLGKNACTSHKIEARDLYNLVLKDIQELA
                     AQAMKDADAFYQRLSSRMERRYLVDASQTEKERKRLEDRNQEIDGMFLSLYTDKAKGV
                     LTEQRFMKLTAALEQEQEANQKRLHDLAVMQSRADAQESEVRTFIKEIRRYAAIAELD
                     ESVLNRLISKILIGEVKKVDGQKVQEVRIVYNFVGEIPEIAA"
     gene            complement(60842..61009)
                     /locus_tag="KRQ43_000299"
     CDS             complement(60842..61009)
                     /locus_tag="KRQ43_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008978104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740675.1"
                     /translation="MEKSKNQKNKVRFVVVREFSGEKSMREAFEQLIERQTCEHFEEW
                     RHQREMAEKAA"
     gene            complement(61277..62635)
                     /locus_tag="KRQ43_000300"
     CDS             complement(61277..62635)
                     /locus_tag="KRQ43_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015559850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
                     /protein_id="HBH2740676.1"
                     /translation="MSAAEALAPEQSVDEVREGLSVTEKGQPANTIGNCRTVFSHDPL
                     LRDAIRLNLLTDRVDIVRDLGWRRNTSALTDTDVKYLLLYFEQNYGLTSEKKMTAALS
                     IVANENCYHPIQDVLNGLVWDGTPRIRSCLHHFLGAEVSDYVEEMLKHFLLGAIRRVF
                     SPGSKYEEMLCLVGGQGAGKSSFFRLLAIRDEWFSDDLKKLDDDRVFLKLQGHWIIEM
                     SEMLATSSAKSIEEIRSFISRQKETYRTPYEAQPKDRLRQCVFGGSSNTLDFLPLDRA
                     GNRRFLPIMIYPEKAEVHILEDEDASRAYLLQVWAEAMTIYRSGKYSMKFSKSIQRQL
                     VEVQKDFMPEDTEAGQIQGFLEHYTGSMVCSKQLFKEALGHTYDEPKRWQLHNINEIM
                     NTVVTGWKPFSNPRMFAGYGRQKGWERDVSGNELPGNEDGFVELSEEECRQLELPKEW
                     IA"
     gene            complement(62595..63281)
                     /locus_tag="KRQ43_000301"
     CDS             complement(62595..63281)
                     /locus_tag="KRQ43_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBH2740677.1"
                     /translation="MKTGCLFLCLEVRKSNVFEAVKQAVPTRQAAESYGIQLGRNGMT
                     CCPFHDDKHPSMKVDRRFHCFGCQADGDVIDFTARLFGLNKKDAALKLAEDFSVGFDA
                     KGHDPPRRKPGKRKISEELRYRQAEQKCFRVLCDYLHLLERWEKEYAPQTPEEAWNPL
                     FVEALQKKPYTEYLLDILLSGSMEERACVVAEYGKEVRKIEQRISEFTASHPAGRHER
                     SRSFSAGAER"
     gene            complement(63297..64541)
                     /locus_tag="KRQ43_000302"
     CDS             complement(63297..64541)
                     /locus_tag="KRQ43_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/arginine repetitive matrix protein 2"
                     /protein_id="HBH2740678.1"
                     /translation="MKLTRHNGRSGKHGTYNPRHNDRRFDVENSEHIDAERARQNVYW
                     DCYRGFTTHEFRENPEQPDFSFEEIERMYYNEHYGGHVEAQNARNEKTRHTERNRTVE
                     DLLKNNKTCPEESIYQIGTMGESVPPDTLFSIVNEFYEEFERRFGSHIHILDWALHLD
                     EGTPHIHERHVFDCENRYGELCPQQEKALEELGIPLPNPEKPKGRNNNRKQTFDAVCR
                     TILFDIARRHGLHLDQEPSYGGRDYLEKQDYILMKQKEQLAAQEQKLEELTLKIEDVE
                     TLLDDVSDAAYDKAVEVVTDTVRQETHKEDIRLVEESKKWVLSPERKAPKKEREYAAE
                     RLDGVITKIKNAMQHALAKIQRTLMQPEVKQAGKEQVKKKAKESIMDILAKAKINADR
                     DNRERWEREGRIAPTKKNDIEL"
     gene            complement(64969..65274)
                     /locus_tag="KRQ43_000303"
     CDS             complement(64969..65274)
                     /locus_tag="KRQ43_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HBH2740679.1"
                     /translation="MRKLSKYEKETIINWNEAENLASVYTFNASLKRRLADFSRKYPL
                     LCRLERSTPEGSVTYVLDKSRLSIRLVPPYSEERKAAASAYAKEHGFQVVGAEEKIA"
     gene            complement(65258..65551)
                     /locus_tag="KRQ43_000304"
     CDS             complement(65258..65551)
                     /locus_tag="KRQ43_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740680.1"
                     /translation="MTLSMKEKKILYAYGCPSHHNTVTRLKWLTALTVDPEAKRRMLG
                     LARKVETEVGENWYEDFYHHLRMEMDEYRRLKRSLRVLKSYTDYEEDLYEEAV"
     gene            65917..66765
                     /locus_tag="KRQ43_000305"
     CDS             65917..66765
                     /locus_tag="KRQ43_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740681.1"
                     /translation="MYAKLTIPERLKDLRVVDKHLTLEQLAEQTGLSKSALGKYETDD
                     YKDISPFAIATLADFYGVSTDYLMGLTENKNHPNIELQSLHLSDDMVELLSSGKINNR
                     LLCELATHPNFRRLMIDMEICIDQIANMRVEQMNLVLEATRQTVMNKYAPGEDDLYMR
                     TLELGQVQESDFYSHVMHDDLDSIVRDIREAHRKDKTTADPQPTLDDVKEKFEQAIGQ
                     GSDTEMLIHEFCDKLQIPFEKISSEDFSAFLRILSLSKQLKSSNNMRGKASPIPPNRK
                     ARRKRK"
     gene            complement(66887..67168)
                     /locus_tag="KRQ43_000306"
     CDS             complement(66887..67168)
                     /locus_tag="KRQ43_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740682.1"
                     /translation="MILEEMYNGRFYPCETVVADSPRFKQAVKASAALMDTLSERLSK
                     EDYALVEELREQVAIAQCEENESHFKYGFSAGLLVQQEAHAQVSQKDKE"
     gene            complement(67182..67559)
                     /locus_tag="KRQ43_000307"
     CDS             complement(67182..67559)
                     /locus_tag="KRQ43_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HBH2740683.1"
                     /translation="MEHLPKKIHHNGISYTLVGDYYIPDLKLSEEIRPIGRWGRIHKA
                     FLQEHRPGQYNELLLSGKLWTYLADLNEQADDRLACIISQMQAAEGVTEELKARDQLA
                     WVGGMNSIRSRVEEIILSEMIFV"
     gene            complement(67612..68238)
                     /locus_tag="KRQ43_000308"
                     /pseudo
     CDS             complement(67612..68238)
                     /locus_tag="KRQ43_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891895.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            complement(68333..68698)
                     /locus_tag="KRQ43_000309"
     CDS             complement(68333..68698)
                     /locus_tag="KRQ43_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740684.1"
                     /translation="MLYTEKEKHEIERVKEVFAEHLRQSPDFELLWSDKVGYVWLAIG
                     VNPVYVDTGTRIESAADLCYRCLDDVATDVLYMTGNDHALEAADPLELAEIKRRWEPY
                     INQLPDYAYLCKDLLNGKM"
     gene            complement(68776..68970)
                     /locus_tag="KRQ43_000310"
     CDS             complement(68776..68970)
                     /locus_tag="KRQ43_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019161305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HBH2740685.1"
                     /translation="MNKEPRTMQVSDAATASRAPENTPAMVKKIGKTTYKVHVHFSNT
                     STETMSDKIKRMLKNEIQQM"
     gene            complement(69014..69877)
                     /locus_tag="KRQ43_000311"
     CDS             complement(69014..69877)
                     /locus_tag="KRQ43_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2740686.1"
                     /translation="MIEITAEIRAFIDKAAAGVELAEDEYIDPSDGLIHCKKCGGQRQ
                     TVVPCFGKSGYFMPRCICQCQREAEEQRKAAEERQRRMERIKRRKAQGLQDRYLYDYT
                     FANDNGQNPLMDKARAYVENWKEAYKSNIGLLLFGDVGTGKSFFAGCIANALLDRDVP
                     VLMTNFPTILNRLTRMFSEDRSEFIASFDEYDLLIIDDLGVERSTEYAMEQMFFVIDS
                     RYRSRRPMIITTNLKLSELKNPPDLAHARIYDRILERCAPILFDGKNFREENAGATRQ
                     TAKDIVNSKHD"
     gene            complement(69874..70608)
                     /locus_tag="KRQ43_000312"
     CDS             complement(69874..70608)
                     /locus_tag="KRQ43_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015536522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBH2740687.1"
                     /translation="MSDNRKYYYLKLKENYFDDDSIVLLESMQDGVLYSNILLKLYLK
                     SLKHGGRLQLDEDIPYTAQMIATITRQQIGTVERALQIFLKLGLVEVLDSGTFYMSNI
                     ELLIGQSSTEAERKRAARLQNKALSAPRTNGGHLSDIRPPEIEIELEKEIEIKREIEK
                     GRSARAYGRYQNVFLTDGELADLQASFPTVWSQYIEKLSEYMASTGKRYQSHAATIRR
                     WAGEDAKKTVTPSRNRDYSVKEDETV"
     gene            complement(70722..71120)
                     /locus_tag="KRQ43_000313"
     CDS             complement(70722..71120)
                     /locus_tag="KRQ43_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBH2740688.1"
                     /translation="MKNNKSEPIPVMDYRQYRRARRLVHECCNYIGGNCIALDDGEKC
                     VCVQSISYSLLCRWFRTAVLPQDKELETALFHRLNAKKCAVCGALFTPGSNRAKYCPE
                     CATRMKRINAAKRKRKQREKCHALGAEKPL"
     gene            71247..71525
                     /locus_tag="KRQ43_000314"
     CDS             71247..71525
                     /locus_tag="KRQ43_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005924829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBH2740689.1"
                     /translation="MAGNTTNISIRMDADLKAQADALFTELGMNLTTAFNIFVRQSLR
                     EGGIPFEVRLEQPNKETVAAMLEAERIAKDPSVKGYNDLDELFADLKR"
     gene            71522..71812
                     /locus_tag="KRQ43_000315"
     CDS             71522..71812
                     /locus_tag="KRQ43_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HBH2740690.1"
                     /translation="MKETKYTVKYTTSFKKDYKRAIKRGLKIELLEQVVALLAMGEPL
                     PDKNRDHDLSGDWAGHRECHILPDWLLVYRIEDDVLVLTLARTGTHSDLFGK"
     gene            complement(71920..73365)
                     /locus_tag="KRQ43_000316"
     CDS             complement(71920..73365)
                     /locus_tag="KRQ43_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HBH2740691.1"
                     /translation="MFPIDFCHIPVSIIKRSAGRSAVAAAAYRSGTKLTNEWDGMTHD
                     YTRKGGIVHAEIMLPAHAPPEFADRSILWNSVEQIEKARDSQLAREIEAALPRELSGE
                     QQLALVRAYVKDNFVDKGMCADFAIHDKGTGNPHVHIMMTVRPLKENGAWGAKCRKAY
                     DLDENGQRIPDGKGGWKNHREDTTDWNDKGNVEIWRAAWAAYTNRALESAGRPERIDH
                     RSYKRQGIDKIPSVHLGPAASQMEKRGIRTDKGEVNRQIAADNKLLKEIKARITRLYN
                     WSKAEAEKPEGQQPSMIDLWEAQQQLKRPDTRTGKIRALQESAALFSFLQANGIQSMQ
                     QLHEKIADMNSRYYDLRGKIVKAERRIAILTERGEMWEQYNQYKSIHKQLAKVKPEKR
                     EQFEQRHSRELILYDAAARYLKELKDSGEGITPKAWQLEIDQLAAGKQTDTLAMKSMR
                     EDLKSVERLRKTAEQLSRQERDKPHDREPDR"
     gene            complement(73552..73842)
                     /locus_tag="KRQ43_000317"
     CDS             complement(73552..73842)
                     /locus_tag="KRQ43_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008791598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HBH2740692.1"
                     /translation="MNEKITAHPQKEEREKVLKEIRQLENRKKILENKQRNEERRVRT
                     RRLIERGAVLEGIFPLAPDLSGAEVKAFLIALSHLPGAAELTANLPKSGDTP"
     gene            complement(73871..74332)
                     /locus_tag="KRQ43_000318"
     CDS             complement(73871..74332)
                     /locus_tag="KRQ43_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2740693.1"
                     /translation="MQTINLKQYYPFCKEDIFVEVSDEIVEAFLLDKRAEAARDRKMF
                     RYKAFYSLDCNDGIENAAIGWAQPSPEDYLIEKEELAEYEELIRRLYEAISSLPPMQA
                     RRVHARYMLGMKVKDIAAMEGITPSQAGKSIHAALRRLRRYFARQKWTVNL"
     gene            complement(74343..74795)
                     /locus_tag="KRQ43_000319"
     CDS             complement(74343..74795)
                     /locus_tag="KRQ43_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019161297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-24"
                     /protein_id="HBH2740694.1"
                     /translation="MKTINLRWMYPHYRHDEFVDVTDEVWAAMYQAKREMENYERRKV
                     YHRAYYSLDAYSWLENYALEHSRSPEDILLEREEMTTRLHLIAALPVALAHATPTQAR
                     RVHAYYIAGIKQPEISRREGVHSSKVSVSIRRGLRNMRRCYDGLFQTE"
     gene            complement(74897..75310)
                     /locus_tag="KRQ43_000320"
     CDS             complement(74897..75310)
                     /locus_tag="KRQ43_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019161296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2740695.1"
                     /translation="MEVTINYNGQAVAVEVTLEVYEFLDRADHKTENLFHEQRRHWDG
                     REFDEYIAFTEGVGVYSETPEEYLCRMETLHELMAVLDTCTEAQRRRFLFYALDGLSL
                     AEIGVLCGCSKVAVYQSVEAVRKKFINFFENRLNE"
     gene            complement(75755..76216)
                     /locus_tag="KRQ43_000321"
     CDS             complement(75755..76216)
                     /locus_tag="KRQ43_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740696.1"
                     /translation="MKKIVLALAFVLLGSFMISGCSKDEILNHYNNIVQSAGSIELTG
                     KSSLQGEKEKGIDDYTGTYTADYANFSGTEYLFGGTSIKREAGKELSIDCTLEITEGT
                     AKVFWISGSDEAVTLIEATGTYSDTITLPDGGNYIGIECENFTGNIELNIE"
     gene            complement(76224..77003)
                     /locus_tag="KRQ43_000322"
     CDS             complement(76224..77003)
                     /locus_tag="KRQ43_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009255077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2740697.1"
                     /translation="MVRIVKTEFYKLKRYHILWAGVALMLLSVLLTLFTSMANDGSVW
                     DFAYLTEQVIKNNMSMIFPMCISLIAGYMISREQTDDTLKNILTVPISFKKLLTGKLI
                     VCGVLSIIFGLICSLFTIIAEMIVGFPGFEISLALKAALQITAVNFFLYLAVLPIIAL
                     TCRRAGSFLVGVIIAFVYGYGGMFAAGNMTLANLYPITASLGMVGYRSYDTAVNWNIG
                     TCSCSLALAVVISAILILCMKEREATQTKKKAKKVAPKKGW"
     gene            complement(77006..77791)
                     /locus_tag="KRQ43_000323"
     CDS             complement(77006..77791)
                     /locus_tag="KRQ43_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006874368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2740698.1"
                     /translation="MLKLIKCEFLKLKRKKFIPLIILAAFLFPIPLTYLMTTPSMMER
                     YTDRADAFDGLFNMVLGYGIQFLLPCIIGVIAAILFFMERDNDTFKNLRTIPVTSTQM
                     VLAKIIVLFLFGIVFCVASTIATILCGIGTLEVYGIGYKLFLAVETGIFITAGTLPLI
                     VLVVFFSKTYVFSILLCVFYSVLNMSATALFDTLPKTMLWLLPTPLTTFWSAGDMAAH
                     GIKMDLEQMTGLIPSTFQVVFILGIMALVSFLLIDRLYKQRGE"
     gene            complement(77784..78710)
                     /locus_tag="KRQ43_000324"
     CDS             complement(77784..78710)
                     /locus_tag="KRQ43_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2740699.1"
                     /translation="MDTNYIIETKNLTKQYGSQKSVADLNIHVKRGRIYGLLGRNGAG
                     KTTTMKMLLGLTKPTSGEVKIWGKSLQGNEKKLLPRIGSLIESPGFYPNLTATENLRI
                     FATLRGVPNSHAIRDALDLVGLPYKDKKLFSQYSLGMKQRLAIALAVMHDPELLILDE
                     PINGLDPIGIAEVRSFIRELCDARGKTILISSHILSEISLLADDIGIIDHGALLEEES
                     LAELEQKSSKHIRFTLSDTAQAARILERNFHENHFSIQDDHNLRLHNLDLPVGKIVTA
                     FVENGLEVSEAHTCEESLEDYFKRVTGGEGIA"
     gene            complement(78845..79762)
                     /locus_tag="KRQ43_000325"
     CDS             complement(78845..79762)
                     /locus_tag="KRQ43_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2740700.1"
                     /translation="MEIIVFLSIVIAVVAVLTSIVLVRRVKKQIAEMTDVLVDVKNGN
                     GNRRILSATNELTAPLAYEINEIVVAYESRLSTVRQTEETNRQLMTSLSHDVRTPLTT
                     LLGYLDATHKGLVTGKDRDDYIETARRKAHDLKEYIDVLFDWFKLNSNEFALEIQSVE
                     VAELTRNILIDWIPIFEDKQVDYDIDIPEQPVRVRLDMDSYMRIINNLIQNVIAHSHA
                     DKIKISLSKKENNMELLLADNGVGIEKEDLKHIFERLYKCDKGRSEKGSGLGLSIVHQ
                     LVEKMGGSITVESLPGKGTEFMLLFPLES"
     gene            complement(79768..80460)
                     /locus_tag="KRQ43_000326"
     CDS             complement(79768..80460)
                     /locus_tag="KRQ43_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740701.1"
                     /translation="MNKILIIDDDKELCALIKRSVQAENIEADFCNTGKEGLQKLREQ
                     EYQLVVLDVMMPGMDGFETLEEIRKEYSLPILMFTSKNDSISKVRGLRAGADDYLTKP
                     FDMDELIARIASLIRRYTRFNQQAGAIQKLNFDGLQIDLENRSATTSNGTFELPPKEF
                     DLLLYCAKHQGKILTKQQIYEEVWGEEYFYDDSNIMAIISRLRKKLEVNPSSPKYIQT
                     VKGIGYRFNKEV"
     gene            complement(80453..80641)
                     /locus_tag="KRQ43_000327"
     CDS             complement(80453..80641)
                     /locus_tag="KRQ43_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015540979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2740702.1"
                     /translation="MDYMTLKEAAEKWGVTPRRVNYYCAAGRIPGAVKMATIWLIPKD
                     AEKPIDGRTKQGKELRHE"
     gene            80786..81154
                     /locus_tag="KRQ43_000328"
     CDS             80786..81154
                     /locus_tag="KRQ43_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740703.1"
                     /translation="MAKVEDCPGFETFGADVKAAREARRLARKTLAEMVGIEWRYLAN
                     IENQGAIPSLPVMIQLIKVCGLPVERYFNPEIMREESEQRQRVSHKLKLCPEEYLPII
                     EGAIDGALKMEQTAKQKEDA"
     gene            complement(81182..81481)
                     /locus_tag="KRQ43_000329"
     CDS             complement(81182..81481)
                     /locus_tag="KRQ43_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740704.1"
                     /translation="MLTFEKILKVFQAYLDDDPLYEVVQTSHGYTLMAWEPHRNDWYS
                     AEIQKTPEDLRNALLGTYANFLEDKITGNDRDLTVTETGEIQQRCRELLEKCREP"
     gene            complement(81498..81851)
                     /locus_tag="KRQ43_000330"
     CDS             complement(81498..81851)
                     /locus_tag="KRQ43_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HBH2740705.1"
                     /translation="MSKLTYIRCGDYDIPNLKLSEQPETSIGKYGRMRKSYLKEHRPI
                     LYNHLLMSEKLYPHLLEIERTAQGRVETMLPHMMEVAGVTEELKACDPMRWVGLMNTL
                     TAQIEEILIRELICS"
     gene            complement(81878..83758)
                     /locus_tag="KRQ43_000331"
     CDS             complement(81878..83758)
                     /locus_tag="KRQ43_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HBH2740706.1"
                     /translation="MRNEKITPLYERLSRDDELQGESNSISNQKQMLEDFARRNGLPN
                     PTHFTDDGISGTRFDRPGFLAMMEEVEAGRVEAIVIKDMSRLGRDYLKVGQVMEVLRQ
                     RGVRLIAINDGVDSLKGDDDFTPFRNIMNEFYARDTSRKIRSVFKSKGMSGKHLTGTV
                     IYGYLWDEKREHWLVDEEAAEVVRRIFSLTLEGYGPYQIAYKLSTDRIEIPVVHLARF
                     NEGVNRSKPVKDPYGWGSSTIVNILKKREYLGHTINFKTRKHFKDKKSHYVSEDEWTI
                     FENTHEAIIDQQTFDLAQKIRSNVRRYPNGWGEAAPLTGLLYCADCGGKMYVHRTNNG
                     KRVSQYTCSNYTKVPCGTLCPTQHRINESAVLTLVSDTLRAIAEYSRNDRTEFIHTVQ
                     ETQVAQQSADISKKRRRLAAAQKRAGELEKLICKIYEDNALGKLPDARYKALDAQYAK
                     EQDALEIEIAELEKAVTGYEQSQKSAEKFIALIDKYENFDTLTNTMLNEFVEKILVHE
                     RARKGSQDTTQEIEIYFNFLGRYIPPSLQPVPLTPEEQEELRKKEERKDRLHQNYLKR
                     KASGAQKQYEDKIKAKKKAEMDAKKALIRAEDMKKGVFSTIGQLPKEEPRKGSIAASA
                     AV"
     gene            complement(83831..84835)
                     /locus_tag="KRQ43_000332"
     CDS             complement(83831..84835)
                     /locus_tag="KRQ43_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBH2740707.1"
                     /translation="MIDKILKDIKGLFKVQDKAKFLKQNIPYLAFFYVGNIFSHHVRA
                     YTGGDVIDKIFQGILELNTMSFLPSIHPTDILMGVVVAVLIKIIVYTKGKNAKKFRQG
                     KEYGSARWGTKKDIEPYMDEKFQNNILLTQTERLTMNGRPANPKYARNKNVLVIGGSG
                     SGKTRFYVKPNLMQMHSSYCVTDPKGTIVLECGKMLEDNGYEIKILNTINFKKSMKYN
                     PFAYLRSEKDILKLVQTIIANTKGEGEKSGEDFWVKAEKLYYTALIGYIFYEAPREEK
                     NFATLLDMIDASEVREDNETYMNPIDRLFEALEKKEPTHFAVKQYKKYKLAAGDICSK
                     "
     gene            complement(84832..85317)
                     /locus_tag="KRQ43_000333"
     CDS             complement(84832..85317)
                     /locus_tag="KRQ43_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBH2740708.1"
                     /translation="MINEEIARKTLNMEINAGKVTGKVLLNLLKKLMKEAEKFGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKNKETGKNSVF
                     FQAKDMKVMDKAFKHALSKSEKKAERKESIHKNIEKFKEMAKNSISKEKIKNKQKEQS
                     L"
     gene            complement(85319..86341)
                     /locus_tag="KRQ43_000334"
     CDS             complement(85319..86341)
                     /locus_tag="KRQ43_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH2740709.1"
                     /translation="MYLFDEQPIVANKTLAREIGLNEALILQQINYWIEINKKSGKNY
                     HDGKYWTYNSIRAWQENDFDYMSFDTVKRTFSKLEKAGYLLVGNYNKDPRDKTKWYTI
                     NNDKLEELYMDMDLKKQKIQTEALKNSMPNALGQNAPMDKGKISQCNNADCTNAQVQN
                     ALMQKDNLHQPLPENTTNNTTNNTTNNSAYISIHPSIKEKNQLFSENMKGGRIDISYK
                     NIYQNCLEELRHQTGYYEHMSIGNKSVAEEFDEILKILADVMVLDDESFITINQTKIS
                     VQVVKERFRKLNSGHLEYLVGVLRENEYRIRNIRAFVLTAAYNAPSGIDAYYSALVSY
                     DMRGGY"
     gene            complement(86427..86708)
                     /locus_tag="KRQ43_000335"
     CDS             complement(86427..86708)
                     /locus_tag="KRQ43_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740710.1"
                     /translation="MRWILKIILFPISIALSILIAFLSFLLGIGTAILYLLMMFCIFG
                     AIASFLQKEVTIGIEALILGFLLSPYGIPMVGTAVIAVLTGVKEAIRSI"
     gene            complement(87018..88268)
                     /locus_tag="KRQ43_000336"
                     /pseudo
     CDS             complement(87018..88268)
                     /locus_tag="KRQ43_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
     gene            89059..89379
                     /locus_tag="KRQ43_000337"
     CDS             89059..89379
                     /locus_tag="KRQ43_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH2740711.1"
                     /translation="MEKIMNFLKENSTFYFATVEDNKPRVRSFGFIMDYEGKLYFGIV
                     KYKTSYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAK
                     NSLV"
     gene            complement(89328..90074)
                     /locus_tag="KRQ43_000338"
     CDS             complement(89328..90074)
                     /locus_tag="KRQ43_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBH2740712.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNSIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(90092..93529)
                     /locus_tag="KRQ43_000339"
     CDS             complement(90092..93529)
                     /locus_tag="KRQ43_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH2740713.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPIFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEISKQL
                     YKNKTIELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENILGGIIITEFNDDFTIKYTNSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIIDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSEMVKTISNSIIHKDNKEVFLNTFLCKNLLSAYNKNITEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIKLKLKAERDTLTGLYN
                     KGTTENLINDFLNSDEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKHLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENTKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNNCIYQNELENNISDNNIKLANK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSER
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            complement(93562..95043)
                     /locus_tag="KRQ43_000340"
     CDS             complement(93562..95043)
                     /locus_tag="KRQ43_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH2740714.1"
                     /translation="MKKNRLIIKNISIAFIVLFFFSVFTFFYIGNISRVLEYETNDIM
                     TVTITGWIILSFLFLCIIIYILYSKAKSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTNINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIIANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLLEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFLKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            complement(95311..96150)
                     /locus_tag="KRQ43_000341"
     CDS             complement(95311..96150)
                     /locus_tag="KRQ43_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBH2740715.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            complement(96171..96704)
                     /locus_tag="KRQ43_000342"
     CDS             complement(96171..96704)
                     /locus_tag="KRQ43_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBH2740716.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            complement(96716..97525)
                     /gene="aroE"
                     /locus_tag="KRQ43_000343"
     CDS             complement(96716..97525)
                     /gene="aroE"
                     /locus_tag="KRQ43_000343"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH2740717.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRIFEILNIESAYKNFEIPKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            complement(97572..98768)
                     /gene="pheA"
                     /locus_tag="KRQ43_000344"
     CDS             complement(97572..98768)
                     /gene="pheA"
                     /locus_tag="KRQ43_000344"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBH2740718.1"
                     /translation="MEDLTRYRNEIDNIDKEIIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAIDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKTISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYELEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAENNINMTKIESRPMKNASWRYFFYIDFECSIYNSKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            complement(98771..99850)
                     /gene="aroC"
                     /locus_tag="KRQ43_000345"
     CDS             complement(98771..99850)
                     /gene="aroC"
                     /locus_tag="KRQ43_000345"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBH2740719.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDKIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQRDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            complement(99828..101141)
                     /gene="aroA"
                     /locus_tag="KRQ43_000346"
     CDS             complement(99828..101141)
                     /gene="aroA"
                     /locus_tag="KRQ43_000346"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBH2740720.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNSTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            complement(101141..102205)
                     /locus_tag="KRQ43_000347"
     CDS             complement(101141..102205)
                     /locus_tag="KRQ43_000347"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBH2740721.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            complement(102227..103240)
                     /gene="aroF"
                     /locus_tag="KRQ43_000348"
     CDS             complement(102227..103240)
                     /gene="aroF"
                     /locus_tag="KRQ43_000348"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH2740722.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKIVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            complement(103370..103525)
                     /locus_tag="KRQ43_000349"
     CDS             complement(103370..103525)
                     /locus_tag="KRQ43_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740723.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
BASE COUNT        28207 a        22649 c        17535 g        35181 t
ORIGIN      
        1 acagaaatat ctgctgatga acttacctct gcttctgatg ttgaagtatt gttatttaga
       61 tttgggtcag gtgtagttga acttactgtt gctgtattta taattgtacc tattgctgtt
      121 tgacttactg ttccccttat tatgatattt cttatctctc cagcatctaa agtacctata
      181 ttaaggcttc cattccatgg ttggaaagtc actccattat ctattgagta ctctggattt
      241 aaaatagaag ctggtatatt atctgttaaa gttacgttct ctgcaaaaga tggtcctgca
      301 tttgcaattt caattccata aataaatctt ccccctggta tagcaactgg ttcgttgcct
      361 tttatcacag aaatatctgc taatggactt atatctgttt catctgttga agtattatta
      421 tctggatttg ggtcaggtgt aggtgaactt attgttgctg tatttataat tgtacctact
      481 gctgtctggc tcactgttcc tcttattata atacttctta tttctccagc atccaaagtg
      541 cctatactaa gatttccatt ccatggttgg aaagttactc ctccatccaa tgaatactct
      601 ggatttaaaa taacatctgg tatatcatct gtcaaaacga tactttgtgc agcagatggt
      661 cctaaattta taactgttat agtataacta aaagtttctc ctggaactgc tgtatccata
      721 ttgctagttt ttattacttc tatatctgct gatggaacta taggagttgt cactgttgat
      781 gaatccgtaa ctggttctgg tacatctgca cttacttctg ctgtattagt aatatctcct
      841 gtagcagttg aacttactaa tccctttatg ataattctta ttaattgccc tggtgcaact
      901 gtacctatat taagacttcc attccatggt tggaaagttg ctcctccatc caatgaatat
      961 tctggattta aaataacatc tggtatatca tctgttaaaa ctacattcgt agcattagat
     1021 ggtccttcat taaaaatttc aattgtatat acaaattctt ctcctggaac agctacatcc
     1081 tcgtcagcta cttttataat agaaatacct gcttgtgggt taactggtgt aataatggta
     1141 gatatattgt tgcttaaatc tgggtcaggt gtagttgaag aaactgttgc tgtatttact
     1201 atatattctg aagaatttaa actaactgtt ccttgaatta aaactgttaa tgaaattcca
     1261 gagtttaaag ttcctatatt aagacttcca ttccatggtt gaaaacttgc tcctccatcc
     1321 aatgaatatt ctggatttat aatagaggct ggaatatcat catttaatat tacattttca
     1381 gcatttgctg gtcctaagtt ttctacttga atagtatatc tcaataaagt acctggaaca
     1441 gctgaattag gttctgctgt tttcattact aaaatatctg ctaataaatt cacttctgtc
     1501 tctattgtag atgtattatt attaaggttt gggtctgctg tagttgaaga tactacagct
     1561 gtatttgtta taattcctac tgttgatgga tttacaatac ccctaattat aataactctt
     1621 gtctctccta cttctaatgt ccctatattt aaacttccag tccatggttg aaaagttact
     1681 cctccatcta atgaatactc tggatttata atagaagctg gtacatcatc tgttaaaacc
     1741 acattctcag atgggaatgg tccattattt actactttta tagtgtatat taattcctct
     1801 cctggattca ctatagtagg ttcagataat tttgtaactt caacatctgc tgagattact
     1861 tcaacaggaa ctggattaga atctactgaa aaatcatttg gtataccgcc ttctacaggt
     1921 gtataggagt aatctatagt agctatatta ttagtaggat ttgggttagg aatactttca
     1981 accacaacat caaaagttac ttcaacccct attcctcctc caatatctgg aagtggaaaa
     2041 cctgtattag ggtctactcc tggtacagat actccatcaa cttgctcatc attttccaaa
     2101 cttatattaa gatcttcatc aatgataggt agcttaaaag taatggattt tagccattgt
     2161 ccattaggct gcttttcttc ataaatttga atttctgaaa tgagtgcttc tattaactgc
     2221 ctgcgttcaa catcgttcat gactttataa agcttgtcaa aataaatcaa tactttatat
     2281 atgttatcac cagtaagttt ctcaacctct atcgtttctt tttttgcttt agcttctatt
     2341 aactgacttt ctaattcctc aattttatcg tacatacgat aaagcctatc atctaaatca
     2401 ttttttcttc tcttataatg tttatcctct acatctaaat tatctatttc ctcaataagc
     2461 ttatactttg tagaatgact ttttcttagt tcattttggt aattatctat ctcattttca
     2521 atagcagatg tatcaacctt catgttaatt ttttcttgta tcatagatgc aaatttaggg
     2581 ttgcttacta acttgattat tacctcagca acggcatcat ctaacaattc ttctctaatt
     2641 tgtttattat aggtacattt atgtcctcta ttcataagtc tatgcttaca accatagtaa
     2701 tagaagtctt tatacttcgt cccatctttt ttatatttta tagatttatt cccaaacatt
     2761 ccagctccac atatcggaca ctttactatt cctgataata agtgtgtcct catgttcttg
     2821 cccttattta catgttcata ctttttagct tgtgctttca gtttaacttg tgcagcctgc
     2881 cacaattcat ctgggattat tgcttcatga atgccttctg ctactaaata atcgtcctgc
     2941 tctacttgtc tgtattcatt ccttgtacca tgaacttttt ctaaagttct tcttccaaat
     3001 gctattttcc cgttatacac aggattcttt aatatttttc ttataagacc tgcgtcaaac
     3061 aatggatttt tcccattttg tcttggtatt ttccttatac catgattttc taaatattta
     3121 gaaagaccat tagctccaat acttgtattt acatattgat caaaaatagt tcttattgca
     3181 attgcttctt cctcatttat tatcaatttc ccatcaataa gttgataacc atacggagca
     3241 aatccaccat tccatttacc ctcttttgcc ttttgaatgc gaccttccat tgtttggaca
     3301 cgaatgtttt ctctttctat ttcagccact gccgataaaa cagaaatcat caatttaccc
     3361 gcatctttag atgaatcaat tccatcttca acgcaaataa gatttactcc aaaatcctgc
     3421 attatttgta aagtcgaaag tacatcagca gcatttcttg caaatctcga tagtttaaat
     3481 acaagaacga aagacactcc atcctttccg gattttatat cttccatcat acgagtaaac
     3541 tgaactctac cttctataga ttttccagac ttacctgcat cttcgtattc accaacaatc
     3601 tcataatcat tatagagagc aaaagccttc attcttgatt tttgtgcctc taaagaataa
     3661 ccatctatct gtatggatgt agatactctt gtatagagat atacttttat tttttctttt
     3721 gacatagcat taacctcaat atccttatta tatatttata tatttttacc aataaaggtt
     3781 tggactttaa tctcaagtat attatagcac ttttatttct ctttctcaat ccgtgctttt
     3841 agctatatca aatttattct tatcctctgt attttttact ggagtaggat ttggaagatt
     3901 ctctaaatct aaaactccag catattttgt aatcagattt gctatcaaat cagccaatcc
     3961 attccagtca ttatccacta atacacctcc tccactttaa attctttata accaaatatt
     4021 atttttctta ctaagtttta tgacattggt aggtgcattg gctgctacat aggaatctca
     4081 cctccgcccc ttgtttcaga cgaggcagct taaactattg aagtatcatt atcaccactt
     4141 acatcatcga aataagctgc cacgcttatc ttttatgtat tcctatctat cgctcatttt
     4201 cttctaacct cggcattatg ccggtattca tttgaaccga ttttcatcag cagaaaagtc
     4261 ttggcgtagg tcataactct cagtaagtag ataaagtcct accttggtct attcagttgt
     4321 caaagatcaa tatttgaaag ggactgtttt ctttacattt tcctatttgc cataagcagg
     4381 cgtatctcct actcaagaaa gtaaaggagg tcaaactccc cttcacttta cataaggaaa
     4441 atttgccccc tttggttacc aaagttttaa agttcttcga taaatttttt cagcttttca
     4501 agaattttgt ttcttctttt gattaaagcc ggatgtgtaa tacttttgag ctttgctact
     4561 gaacgaacag tttcatcatt gaaatacaag cgttcaataa tatctctttc ttctgcattg
     4621 agccttgtta tagcacttct tactgcttca atcatcatct gtgtttcaac aatcttttct
     4681 acatcaacac tttcatcaac aatattatct gtaaagtgtc cgtcatgatc caatgctgaa
     4741 aaaaagagca agtggttttt cctgtccacc tgctctaaat acttctcgtg ttctttttct
     4801 cgccagtaga ctatatatat atcttcactg acttttacct tttgtcctct gatataaaga
     4861 taatactctt ttgccataaa gtttcctcca tctctttttt atctgcttgt ttttcagata
     4921 aaaaaggagg acttctgcat cttggcataa gaagtcctct gaaatgaaag aataaaaata
     4981 tttctttata tgaacttgat tgtttcaatt cgcacctgaa acaatcatct actatacata
     5041 ttataaaaaa gaggaatgta ttgaattcta aatatttcta acattaaacg tttagatgct
     5101 tccatattta tttcctccat tttatcaata atctaaataa ccatcatatt catctactac
     5161 ttatataatt gagttttatt aaacttttta agtttctatt ctatcaaata tttaaacagt
     5221 ctctgcatcc gaaaagacta actcatatag ttttactaac aatattttca ttagcgtgtt
     5281 caaatcctga tttcttgtat caattatttt ctgttcactt tcaataagaa aaaagccttt
     5341 acttccatgg ctaataataa gtctctattt ttcaataact attgcaaaat tatatcttgt
     5401 ttaagaaaat attttaattt taaagataaa aaattcttca tcctgcaatg ctttatattc
     5461 tatattgtaa ttattcagaa tattacttac aatatataaa cctaatccat tactattttc
     5521 cttatttaaa tcaaatttaa catcaaatat tttatccata ttcgaaattt tattgttacc
     5581 gtatgaattc tctatatata accaatcatt aactatccca atattaatta ccccatttac
     5641 atcagtatat tttaccgcat tactaatcaa attagataga ataatcttta aagctgtttt
     5701 tcctatataa acattctcat ctaatatata attattgaca gttattttct tttgatttgc
     5761 taatatttca tactttttta atatgtcttc taatgtatca tttattttca aatattcttc
     5821 atcattattc aaattttcta tagaatgaac tgataatatt tgagaaatat tttttgttaa
     5881 actatcaacg atttcaatac attcattaat ataaatatct ctttctttat attttccaat
     5941 attgtatttc atgttttcca gtattatttt aagactagca agaggagttt taagttcatg
     6001 ggatgcacct ttaaaaaagt catattttaa cttttctaat tttaaaattt ctttattttt
     6061 aaattccaaa tcgtcaattg ttcttaataa agtagaatac aaatcattaa tttgttgttt
     6121 taattctcca acttcatcat tagagctaac ttttaaacgc gtttttttat caagtttcat
     6181 cattttatca gtaacaattt ttatttcttg tatattattt tttattgatt ttgcataaat
     6241 taaagaaata atagcagaaa ataaaattga tattaataaa gaatatggta aaaatttaag
     6301 gcttaaatct ttcgcatctt tttgcatatc agctgtagaa acaaattgta gatttgtttt
     6361 tttaccatca ttaagcttta tttctctttc ttcaattatc aaagaattac tatcactttc
     6421 taaattaaca tttatattat ctttgatttg tatttcattc ttattatttt tttcttttat
     6481 aaatgctttt atttcactac tcttagaata aagctccaaa gtttgttcta tatattttat
     6541 ttcttttcca ttcatattac tagaaatttc atttgccata ttatgaatct tttcttttct
     6601 cgtctccaaa tatgttttag gaaagataaa aaaaactaat gaatgaacta atataattat
     6661 tattccaaga acagaaaata tttgtatgaa catttttgga aatatcttta attttttcat
     6721 tttctctcca atttatatcc tacatttctt atagtagtta tacagtctaa ttgtaatttt
     6781 tttctaagtt cttttatata tacatctatt actcgatcat aaggagtttc ttcgctatct
     6841 ttccatacat aatcaataat ttgcattctt gttaacactt gtccattatt atccaataaa
     6901 cattttaata cttctagttc ttttgcattt acatctattt cttcaccatt tattttagct
     6961 gtatagctat taaaattaac cgatagatca ttatattcaa acttctctaa atgtccataa
     7021 ttcttcttaa ttaaagaatc tattctagcc tttaagaccg gcaatgaaaa tggcttttct
     7081 acatatccgt ctactaaatt agtaaatgca tcaattttat attcttcatc actaaatgca
     7141 gtcaagatta gaattggtaa attgcttttc tttctaattt ctttcaacac ttctaaacca
     7201 tttataaaag gtatctgaat gtctaagata accaaattta tatcgctatt aaattttgac
     7261 aaggcttctc ttccatcttt agcttgaata acagtatatc caaattctga aagatattca
     7321 cttattccct ctcttatcat attatcatct tcaacagtta atattttcat atatacctcc
     7381 acttaagcct ctacacttat attatacagc atattatttg atatttaaaa gccaaaaaat
     7441 ttttggtgct aaaaagcacc gaaaatttta attattgtca attaataatt cttttggatt
     7501 ccttcttaat atattgaatg aagaaataat caatgataca agaagtacta aactcataaa
     7561 tataactaca taaattatga atttaggtaa tacatttata tctaaacttg ataatgtctt
     7621 gttaaatcct tcagcttctg ccccaccacc taattggcta gatgcagatt gtctagctat
     7681 ttgtttagct atatcaccag taaccttatt caatatatta ttcccaagct tatcagctgt
     7741 atattgagct aagaaataag aaccaacgaa tgcggggatt gatataaata ccatctcaat
     7801 taggaattga ccaaaaattt ctaattttga tatacctaat gatagtaata ctgctatttc
     7861 tttctttcta gcattcatcc ataagaataa taataatgaa actacaactc ctgcaaatat
     7921 taatgagcca acaaataatt tatttgaaat tgagtagata cctgatatag attgttgtaa
     7981 tgcagggtaa tttgatgaac ttttaatcaa attatattct ctccaattta tatctaattt
     8041 cccaagatct tttattacac tatcaagatt cttatcacct tttacaaaga atgttgcatc
     8101 ttggtataca gctgtatctt ctgtattacc ataaacttta gcagctgtat gaacatcagt
     8161 gattaatgta ttttcgtata gttcttgtgc tgcacttact ccaccgctat tatgcccatc
     8221 gaatagacct ttaatttcta cttctactgt ttcatctgca cctttctcat tatcagcatc
     8281 aaataaatta gattttattt ttatcttatc tccaacttta agattatttt tttcagctaa
     8341 atctttatgc attaagattt tatttttatc ttcattttct aaatgctttc cttctactaa
     8401 tttatatgct tctgatacaa attttgtttc ttttgatgag tcgttaaccc cagttaacat
     8461 aactgttctt ttaaaattct tcgctctttc aggtgattga ttcgcaagag tctcttgagt
     8521 ttcaataata tcataatcaa ctaaatctgc aacactgttt attcttttta cataggagtc
     8581 tatactatct gtttgaaata tctttttaat atcttcacct tttacatttc ccccacctct
     8641 aggtgttcct ggatttactt gtctatttat ctccatagaa aaactatttg ttatattagc
     8701 aaatgtttct tttgaagctc tgtccgtagc atctttaata gataaactaa tgagacttaa
     8761 agttgacata gataaaataa ctaatataat aattaatgat tttaagcttt ttctagttac
     8821 ataagcaaat gcatttttta tcattattca acctccaaat tcattttatt tacttttttc
     8881 aactttttac cacttagttc taaaatgata tccgcagaat ctgctacttc cttactatgt
     8941 gttacaacta ttacacattt atttctatct ttagctaatg tctttaatat attaattatt
     9001 tctccagcag taacactgtc tagattacca gtaggctcat cagctagtat tattggagca
     9061 tctgatacca atgctctagc aatagctact ctttgttgct gtccaccaga taatttcata
     9121 acatttcttt ttatttgttt tttatctaaa cctagttcaa acaagatact ttcatctgct
     9181 gatttattta ctaatctaat attttcaatt ggtgataaat aatctattaa attatagttt
     9241 tgaaatacta aagatatatt attttttcta tgattactat atcctttctt ttgtatatct
     9301 tcattcttaa acaatatttt tcctgtttga ggtttatcaa gtccagcaag taaggaaaga
     9361 agtgtagatt ttcctgttcc tgactttcct actatcgcat aaaacttccc aagttcaaat
     9421 ttttgattta ctcctgacaa aactttttct ttagaatttg cataactata tgctacattc
     9481 tttatttcta atatatccat tattttctcc taacttattt ttgataatat ttctttaggc
     9541 ttcttgatta atattaatga agaagcaaat acaactgata aaacaataat acttattaat
     9601 attaaataac tttgtccaag tgttgttata tttaacataa aactactatt atttattaaa
     9661 cttccaccgg aaatcattga gtcctctgag ttaatgaatc catctacaat tacttttagt
     9721 aatacatttc ctaaaaataa ggaagatatt atacttggta tcgatatgaa tattaactcg
     9781 aatataaatt gcattataat ttgtatctta gatgttccaa tagataaaaa tatacctatt
     9841 tcataaattc tttctcttaa ccatagaatc aagattaatg aaagaacaac catcccacct
     9901 aacataatag aataagtcat tatttttatt atatgtttta ttccactcac tgactctaaa
     9961 gactcttcaa acgcattaga atctttttca acaaaatact ttgactcatc aattttaagc
    10021 tctttcaatt tgtttaaggc taagtctgta gattctgcac taccagaata cattaaaatt
    10081 ttatttgcga ttttattatt ttctgattta tttaatatct cttggcttgt tgaataatct
    10141 acaaacacca tattttcact aaaatcagaa gataatcctg tatatgtttc ctgtttttta
    10201 ccagaaaaga tccctataat tttaaattta tgacttttta tttttccact tttttcaata
    10261 tctagtaatt caagatcaac ttcatcacct aattttagat tgttttgttt agcaaattct
    10321 tcatgaacaa taattgaatt cttatcattt tctcctatat ttttgccttc tttaattgta
    10381 aatactccac tactaaataa aatatttctt ttagtattat ttgtagcttc gagtgaaaca
    10441 acattcttaa attcgtcaga taaatcttct ctatttattc tttgttctcc gctaactact
    10501 ttagcatctt ttagttttgc taatccatca tattgaatta ttttttcttc aatttctttt
    10561 aatttttcaa tatctttaaa ttgattaaca ttaaaatatt taccatcttt ttttgttatt
    10621 gatattgaag aattagaact ttcatataaa gccttttcta tttcattgct tgatttcatt
    10681 attgttaaac aagaatacaa gcaagaaaga actatagtta atatgataaa aattattaaa
    10741 gttctatttc tctttcttgt aatatatgct atagcatttt ttatcacttt cctaactact
    10801 cctctctatt ttcttactcc ataactaatt gcatccactg gacaagcatt tttacatcgt
    10861 ccacatctga tacactccag atgattgcaa ttctcaactg gatctatatt catttggcaa
    10921 acttttttac attttccaca attaatacac ttatccttat ccaatctata tctaaatatt
    10981 gaaatagggt taaaaattga gtaaatagct ccaagtggac atatatattt acaaaaaggt
    11041 ctatatataa ttatagaaag taacaaagta actattagaa tgattccttt ccaataatac
    11101 aagaaaccta tcgcatttct catactttta tttaataaaa caagtggtaa tcctccttcc
    11161 agcataccaa tcggacaaat aagtttacaa aaatacggag aaccctgacc taaaatatca
    11221 accaaaaata aaggtaatat tattacaaat acaagtaata ttatgtattt caattttctc
    11281 aaatgtttat caaacttaaa tgtttcaact tttttaaaaa agggaatctt atgtagcaaa
    11341 tcttgaatca atccaaatgg acacagccat ccacaaacaa atcttcccac caatgctcct
    11401 ataaaaaaca aaatcccaac tatataataa ctaatcttat attttgaatt tccaattact
    11461 gcctgtagtg atcctattgg acaagaacct tttgctcccg ggcatgaata acaattcata
    11521 cctggaacac aaattttctt taaattccca ccgtagattt taccagtctt aaacccttca
    11581 aagtaagaat tagtaattaa aaaccaaacg gattgaaata aatgcctaaa acgatctctt
    11641 attttatatt tatctttttt tgtactacca tttataatat ttttaattct atccaattcc
    11701 aatacactcc atacaaattc ttatcgcctt atccaagaca actttagttt ctccattact
    11761 atgaccatag taaatcatcg ccatactaat aaagataatt aataaagaca aggcacggct
    11821 ttttaaaaac ttattaacca tataccaatc accgctttac ttttatttat tttttatttt
    11881 ttccaattct ttttcaatta cctgcttcca ttcctttgaa ctctttgccc cagaataagt
    11941 atcacctaca atatttccat tactatcaac aaagaaagtc tctggcatag cctgtatacc
    12001 attcaatcta ccattaaagt ttgtcttatc tggcattaag aaaggatatg aagcctttgt
    12061 cttttcatgt attaactttg acttttcaat tgcttccttg ttttcaccgt tatcatcaac
    12121 agtatctgta acaactccaa cgatatttac acccttgctt ttcatttcat tctgaacctc
    12181 aaccaaatca ggaatttcct ttacacaagc tgtacaccaa gttgcaaata catttaccat
    12241 agtaagatca tacttctcaa aatctttact tgtaaaatcc ttgccattta tgtcctttgt
    12301 tgatagttta cgtaaatctt taaccgattc tttgttaaat gcttctgtat tttctaaatc
    12361 agttttttct gatagcacaa aaccattttt aggacgttct tttttatcta taatttgaat
    12421 ctcagttctt tttaattcat ccagaagatt actttcagct ccgctatttg tgcttaaata
    12481 gcaatcgtat tttccatcac ttgaaactcc tattttagta tgagtatcac attttgtaat
    12541 tttagatatt ttttcttctg atgtattttt ttcgaatata ccaatagtcc caattctttc
    12601 aagctcattt tgccaatttt tatatccatc gcccatcttt tctataactg cattcttttg
    12661 ttcttctgtc attttttcaa atgtcaaaat agcatacttt agttctttat ctataggact
    12721 ttgatcatct aacatcgcta tctttttatc atccatatac tttttaaatt tgtctgaaag
    12781 tttaaattta agacctaaat attcataaac atattctttt tttgttttta aagtataatc
    12841 tgatggctta aatgtttcat ttttatcctt ctcattagtt gacatacctg cctcttcaga
    12901 acttatagat tgtccttctt taattttatt gctttcatta ctttttttac acccaactgt
    12961 acttaagctc aaacataacg taagtaatag gcatgctcct cttgatacta tttttttcat
    13021 aaatttttcc tcctttattc ctcctttatt tttacacaat agcagtttat aactactttc
    13081 aataatattc tacacacctt ttatgaaacg ttgatgaaat ataatttttt atttttccaa
    13141 actatggtat aataatataa atattatgct taaagttgtt cttacacgat tagtatatga
    13201 tcgattagta tatgagcaag cacagtaagt gtacggacac ttacgaaaaa attgatgaag
    13261 cagccctctg ggatatgctt ctttttttat caatttttaa cttgttaggg tataccctaa
    13321 gaccccgaaa tacattcaaa ggaggattta cctatggcaa atagaatacg aaatgaaaga
    13381 ctggaaatta aactaactga agaagaaaag gctctttttg aggagaaacg aaagctcgca
    13441 aggtgcagaa atatgagcca ctttatccgc aaatgcgttt tggaaaagga aatatatcaa
    13501 gtggatttag aaccgtttag agatttacag ggcttactgt ccaatgctac aagcaacatc
    13561 aatcagattg caaagcgtgt aaattccacc ggcataatct ataaggacga tataaacgat
    13621 atgaaaaagc agattgaata tttctcaaaa gagttgtggc aaatacattc tctgcttctt
    13681 aacagaactt ctggaggtga ttaaatctta tggctataac aaaaatacat cctataaaat
    13741 caacccttaa tcttgccatt tcatatattg ttaatggaaa aaaaacagat gagcaaatct
    13801 tagtaagcac tcataaatgc catcaagaaa ctgctcatac ccagttttta agaacacgaa
    13861 atgatgttgg aacaaacgga actgttcttg ccagacacct tattcaatcc tttttacccg
    13921 gagaagcaag tcctaaaatg gcacatcaaa tcggtcttga actgtgtaaa aagatattaa
    13981 aggacgagta cgaatttgtc ttatctaccc acatagataa agggcatatc cacaaccata
    14041 tcatcttcaa taatgtgaat atggtaacag gcaagtgcta tcaatccaac aagaaaagct
    14101 accacaaaat caggtatcaa agcgataagc tatgcaaaga aaacaacctt tctgtgattg
    14161 atgagtttta cgaaagctat aagagaaagt acaaaacaaa tggcaagtca tggtatgaaa
    14221 atgagcaatc taagagaggt acttcttgga aaagcagact tcaatttgac attgatcgtc
    14281 ttataaaaca gtctaagtat tgggaagaat ttctaaaaaa aatggcggag cttggttatg
    14341 aaataaagta tgggaaacac atagccttta aaccaaaaga taagacaaga tttacaagag
    14401 ctaaaacgat tggtgaggac tatacagaag aaagattaaa agagcgtatt acagaaaatc
    14461 aatctattac aactccacct gtcaaaagac gaatcggaaa tatcatcaat atgaatgcca
    14521 atgccaaagt gaaagagagc aaaggctatg aatattgggc aaccaaacat aacttaaata
    14581 caatggctga gtcagttatt tttatcagag aacatggcat taactccatt aagcagcttg
    14641 ataaatacat tcaaaaaagt gctgaagaaa gacaagactt acaagataaa atgaaagaaa
    14701 ttgacaagga tatgcagcta ctttccgata caatggagca ggttcatact gttaaaaaat
    14761 atcgagccta ctacaaagaa tataaagcaa acccttccga taaagcattt tttgaggagc
    14821 ataaggctga aattacacac tatgaaatag ctctttcaaa gctaaaaaaa tcctattcaa
    14881 agctgccgaa ttcaaaggat attttagata aacttaataa actgcaagaa aaaaagaata
    14941 cccttattca agagtattct tctacaaaat ctactatgga cgaactttat caaatacgaa
    15001 agaactatgg aatttacatg ggtaaggaga tggaacgata actctaatat tatatagctt
    15061 tcttattttt ataatattaa attgaaatgc ctatcaatga tgcaagcatt tttataccta
    15121 aagctaaatc aggaattaaa gctacggaag tagtgataaa atgcatactt tttaaacaag
    15181 tagtcaatac ttctttcttc ggatgcttct gcttaatttc attttttata ttatctaaat
    15241 tctgattaag tattgatttg gagttatcat cctccatacc tttaattaag tcttctacat
    15301 tgttaattgc cttgattact tcttcagtat taaatttatt ttcttggtca gcgttaatcg
    15361 tgcttccgtg ttccgcaata ttgacttgaa ctccagaact attaacattg atattatata
    15421 gagcattatt ttcatcgtac cccatatcgg tagaaatatc tttcatataa ttttcaacct
    15481 caagtacaaa cggatagacc attctatcgc caaacgcctt tgccatatct tgatatttat
    15541 tactgccagc ataataccag ccaaaagtat atgtaggtag attatttcct gttataaagg
    15601 aaaatgctct atacagtaga tacgtccttt tattactatc attgccaaga ttcaaaactt
    15661 tacgtccata agaattactt atcgtattta ataagtcatc taagccatca acatcatatt
    15721 ctaaactatg caaatactct tttatcaaca atgtttgctc tatataattt atcatttctt
    15781 ccaaatttgc attctgttct ccataatatg aattcataac atttgaagct aatatcctaa
    15841 attttctact gatttttcta agttcttttt tactaatctc catctatcat ctctccacaa
    15901 aacgggcaat aactaccttc taattttttt atactactta ttctagcggt tttgccacaa
    15961 cacaaatatt tcttttcttc ataatctcca gtttttcttc ctatcggaag ttctgcttcc
    16021 tttttaatct cttttccacg tttaaacttt atacttttac tattcctaaa acttttttca
    16081 agattctttg aaaaatcatt tagcatttca gcaacttgat tttcaactat tcgttctgct
    16141 aattcataaa tatcatcgtc taaataattc tcgtgtgtta aaccacaatt aggacaccaa
    16201 atatctattg tgctttcagc ctcaatatct tccaccgtta acataaattt ttcactacaa
    16261 cttggacatt ttaattgaac atatccctct tcatccgctg gaacagaaat ttcaaatttt
    16321 atatcattag ccatttaaat ttcatctcct cacaataaaa gttataattt caccactggt
    16381 agactacaag gtcgtgcatc tttacgtaca ataacaacac tattctcagc acgtgtaaca
    16441 gcaacatata atctagcctt actttgttct tttagagatg tgttattgtt aataatccaa
    16501 tcccacatcg gttgagtcgg atatataagt actcgttgga attccaagcc ttttgattct
    16561 ccaaaattat aatatggata ttcattattg acggatgtcc ttttattttc tctcaactgc
    16621 attgcattaa atttctgcaa atacttctct acatctgctt tatcaattat cataacacca
    16681 tctgattcat cttcagctct acgcacaaaa tttgtagatg ttctctctgg atacagacta
    16741 ttcgcaaatt tacatataat atcattgttt ctataagtac aattaagtgt cgtttcatca
    16801 attcttacat ctaattttct gcactcattt tttaaaaact catctatttt cccacaacta
    16861 tattttttat atttttttga tgagtgagtt gaatatgtgc attgtctagg atccccgacc
    16921 attatcactt caattcttga agctattaaa cactttaata tttccaaatc ataccccacc
    16981 atatcttgga cttcatcaac atatatacag tcatacattc cactgattct ttcaaaaact
    17041 tttccattac atttatcatt taactctaca acacactctg ataatttatc agtatatacc
    17101 ctgttatctt tggcaaaata tttgttggat gttttcttta cgtacgtatt gttctgtcca
    17161 tttacaaata taattccttc aattcgttcc ttaaatctac ttccttgata aggtctaata
    17221 ccatctttta acaaaaaaga aaaccatgta gaaactgtaa tattattagg aattacacca
    17281 actttattct taattcggct aattatttgt tgctcatttg taatagtata tgttaggatt
    17341 agtatttttt tatgagtatt aagagaatcc tctataattt ttcttgtttt tccagatcca
    17401 gcagcagcta tatataattt cccactcata ttagaatacc ctcctttata tattgtggaa
    17461 attctatagc tttatcactt tcaaaaatct ttaaagcaac ttctgtttta tgccccttca
    17521 tatatttaag taaatcatct ggatcttcat atgatttatt caatatctcg tttaaaatag
    17581 acatggaatt cgatctatat atacacggtt ccaaagtatt atagttgtaa ttttccaaag
    17641 aaccattata ttcatgggta ctatcatcaa aatatatatt tatattctca caacaattat
    17701 ctcctaaata atcgctatat tttctattta gtgcatcaat atttccatca ttatcggtta
    17761 tcactgacac acgtaattct agcaattttg cgatttccaa aaatcttaaa aaagaaattc
    17821 caaccgatat tatatctatt ccatcattaa taggcaattt accattatga gagtccatat
    17881 atgctctttg aacaattagt tcgtccgaat caccttcgac taaaattgct ttatttgata
    17941 ataataatcg taacgtatca taacctgcaa ttcttttaaa aaataaattt gtttcatttg
    18001 ataaatcacc tagccgtagt gtttttcctc gatttagtaa aattaaattt tcaagtccta
    18061 atttatttga tacaaaacta ctatgcgtag taactattat ctgtttttct tttactgact
    18121 catttacttt atctaggaga atatttaagt ttgaatatga caaatggcat tcaggttctt
    18181 ctaaaagcac aatctgctta ttttctattt tatgatcact taatgccaat tgtgttttaa
    18241 caatacattg tgtaccttta ccaatgttat tatatggtat ttcatttaat tgggttacca
    18301 agctgctttc ccatgaagtt ttcgtaccga aatctacaga aattgtcaat tcgttatttg
    18361 atgtttccgt taattttcta tttatattag caatattctc atctctagaa aattgttctt
    18421 tcataagcct atgcgcttgc gatatattaa taatttcatt atcatctaac agattcttta
    18481 ctattctcga tatgtatata tctgacccac tggtaggagt atagcttgtc gtatcaatca
    18541 ttgcagactt aattggaatg ctccttgcag ttatattttc tctggcaaaa gacatccaac
    18601 ttacctcata atattcaatt ggcaacgatg ttatcttgtt cttacaaagc attttatact
    18661 cattgctata tttttcatca aaactaattg ataaacaaat cccaggggtg tctttagttt
    18721 tttcagaatt tccatcacct aaaaaacttg gcatttctgc atcaaaatac gcttcaataa
    18781 ttattttagg aggttctaca ttcactcctt cgttgacttc tctaatatag ttttccacta
    18841 tattcttatt gaaaaggtac tgagtaagtt cattcctaat atttttccca tgataagttc
    18901 cagttaaaac cagattaata gcttccaaaa ttgtagattt acctgttcca ttattgccaa
    18961 ctaatatatt aatcccattt tcaaaatcaa ctataaacca atctgaaaag catttaaaat
    19021 tctttatttt taatttccta attgacattt tatccccctt ctttatctaa tataaaaatc
    19081 atgattttag aatataaata ttgataacta tataaataca gttatgagtt tcctgtttaa
    19141 tcacaatcat aaatttttta tgctacatcc cttaatattt tttcaagcaa taatttaaca
    19201 ataagtttta tgatcctcta gctcctgaaa ataaatctat gactgtaaac ttagactccc
    19261 attctcctta catcttcaat aattacgcac tccataatat cttcaatatc acaatccaaa
    19321 gcattacaaa ttctaagcaa aacatccgta gttacattct gtccattctt cattttgtaa
    19381 aatgtacttt tactcacttt tgccttttcc atcaattcat tatttgtcat atctaaatca
    19441 atgagttttt tgaacaatct tttataacta aaaaccctca ttcttatcct ccgttcaaga
    19501 aaactatatc tagtatatta taccacaaaa tatacttttt tcataaatat attctcttta
    19561 atcgaacttg cataaataaa aaagagccgg tgcagtccta agaccacacc gaccgtaaat
    19621 ttatctctca gcttctttgc ttgcttcttt cttttctttc ggtttttcct tatcttcagc
    19681 ctgatatttt ttgatagctc caagtataga ttctttcttt tcttcctgtc ctttcatctg
    19741 ttcctttgcc tttaacagtt ttgaagaaag tatcctgata ttgctatgct ccttgccgtt
    19801 atcatcaatg gaagttctga tctgcccaaa gagtttgaca aaatctccct gcttaaagtc
    19861 ctttggaata tcactctttt ctccataaac ggagcagttg tgatataact tatttccctc
    19921 atcatcttta gatactacgg agaagtttgc taccttaaag gtttctccgt tcttattttc
    19981 cctttcaatt acatcaactt ctccaacgat atttccgaca atattgataa gattatcctt
    20041 ttcttcccga acataaagca ggtcttttat ctgcccctgt ccccttaaat cctcaatcat
    20101 atagtcaaac tcctcatgca gcaaattaag gctatcattg tccatataag cgtcatatag
    20161 cttatctaaa gcactttcat cattgatacc cttttccatg cttataatcg ctttaacaaa
    20221 gtctttatga ttatcactta acatatcttc aactctatct ctcattgttt tgtaatccat
    20281 gtttttatct cctttcatgg taaaagggag gttgccctcc ctttatctta aaaattcctg
    20341 ctcttttatt ttttgttttt cttctgtttt actttcttcc tgataggctc ttatctgtcc
    20401 taagatagac ggcttatcat ctgatttttg tgtggtttct tctttgctat gaagattgtc
    20461 ctccacatca taagttgact caaaataatc actgtcctta aaatcactat catatctatc
    20521 cggaataccg tcattatcaa ggtcttttgc aaacggatca tagaagttac cctcatcgtc
    20581 aatatcaagt cccgttgcta ctcttaaatc ttcagaatca acataaacca aatcactaaa
    20641 tgtagataac tcaatttcat ttttcatatt tcttagagct tcattttctc ccttattttc
    20701 ataatcaaag ctctctgttt taataggcgt atcatcaatg tactgtgtcc aagttttctc
    20761 ctctaaatta agctcatatt gaataccatg tctttcatcc ggtgtattgg tataggcgat
    20821 accgatatgc tttaagtcag gatatagagt atgaaactca tcataactgt gattttcttc
    20881 atactctctg ttacagaagt caatgattgc tctttttaca tcttccacaa gaggattatc
    20941 atttttcttt tcttccacct ctcccatatc gagcagctta tttaactctg caagtcttaa
    21001 taccttagtt ttcaactcat ctgccttttc aaaaggcttt tttaattcct ctttggcatt
    21061 ttcaagctgt tcttttgtac ttatgagctt ttcttcaagc atatttagtt tctccggcat
    21121 tttctcaagg gcattatcca gtcttgtgat attaccgtcc gcacttgttc caagctctcc
    21181 taaatgcttt gcaacaccgt ttaagctgaa attatgagaa ttagtaaaga agttatagct
    21241 tacctctaaa tccatatttc tatactttcc tataaccttg ctttcattga tttttacctt
    21301 tgaaatagct tcaagtaatc tttctccggc taatttctta tcggtaattt tttctcccgc
    21361 aatggtaata gaagtaaact tttcttcacc ttccgcttta ggctctacat tggatatatc
    21421 ttttttgaca gcttctatga gcttttctgt tcttgcgatt tcttcaggat agttttttgc
    21481 caccttatcc tctaatctgt aacggttaga cttatagttt gcttcaagca ttttaagttt
    21541 tgtaacctca ttatccaaat ccatcttttc tttaatcttt ggatcacccg ttgccaacgc
    21601 tttaatttcg gcgtaattta agctgctttc gtccacatct tctgccacac gaacaggagt
    21661 cttactggtc ataatctgtg aaatgaactt ttgcttattc tctatcgtct gccaaaggta
    21721 ggcatcaaag gtattctctg taacataacg atagatattt accttctcat tttcatttcc
    21781 ctgccttaca attctacccg cacgctgttc aagatcagct ggtctccaag gcacatccaa
    21841 atcatgaagt gcaatcagtt tattttgcac attcgttccg gctcccatct tctgcgttga
    21901 acccattaag atacgaactt cgccttttct tacctttgca aagagttcat ccttttgctt
    21961 atcagaattc gcttcatgga taaaggcgat ttcttctttc ggtattccca ttgctacaag
    22021 tttttctcta atatcatcat agatattaaa ttctccatct ccttttggag tagacatatc
    22081 ggagaaaagt agctgtgttg acctattttc ttttgtctta tcccaaatag caaatacatt
    22141 ttttacgcat acatttactt tactatcagg gttatcagga agtaggggat tgattaaacg
    22201 ctgatctaag gcaagtttct taccgtcatt ggtaatctta agcatattat caacatccgg
    22261 ctctacaacc ctatttctga catcatccgc tctttcagaa aggctcttta ggatttcctt
    22321 ttgttcttca gaaggctcag ttttaataac ttcataatta gcttcaggtg taggaaggtt
    22381 aagcatatcc gcagtctgaa tatctgctac ttccttgaac atactcatta gttcaggcaa
    22441 gttatagaac tttgaaaatc tcgtttttac cctatatcct gttccttcag gagatagttc
    22501 aaaggagctt tgtgtttctc caaaagtgga agcccaagaa tcaaaatgct ctaagtgatt
    22561 tttctttaaa ctctcatact gaagatacct ttgcattgta taaagctctg tcattgagtt
    22621 acttacaggt gttcctgtgg caaaaactat gccttttcct cctgtcattt catccatata
    22681 tctgcatttc ataaacatat cggaggactt aaaggcttct gactgcccga tacctgcaac
    22741 atttctcatt ttggtataga gataaaggtt cttgtaatta tgtgcctcgt caacaaagag
    22801 catatcaact cccagttcct caaaggtaat tacatcgtct ttcttaaaat catcatttaa
    22861 tttctcaagc cttgtttcca gttttttctt tgtcttttca agctgtttta ctgtaaagtt
    22921 ctgatttctg tcatgcttgt attcttctac atagtttacg atttcattaa tctgatcttg
    22981 gatgtgcttt tcctgatatt ccttactcat cgggattttt tcaaactgcg tatgcccgat
    23041 aacaaccgca tcatattccc ctgtggcaat ctttccgata aatctctttc tgttcttcgg
    23101 ttcaaagtct tttttatcag ccaccataat attagccgac ggatatagct gcataaattc
    23161 acgaccgatt tgtcctgtta agtgatttgg aacaacaaac aaagacttac tgcacattcc
    23221 aagtctttta ctttccattg cggaagctac catctcaaag gtctttccac tgcctaccac
    23281 atgagcaagc aatgtgtttc ctccataaag acttcttgct atggcatttc tttgatgagg
    23341 tcttaaatca atttctgtat tcattccctc aaaagaaaga ttgcttccat catattctct
    23401 gtttcggatt gagttaaaac gctcattata cagttttaca agacggtttc ttctttcctg
    23461 atcgttaaat atccagttct taaattcttc ttttaatagc tcctgctttt gtcctgcaag
    23521 catggtttct tttttattta agacagaagt tttagaaccg tccggattta taatctggtc
    23581 aaataccttt gtttctttaa gatttagggc atcttcaatc agcttatagg catttaccct
    23641 tgatgtacca aaggtcattt ctgcaaggtc atttccttta tccctgcttt ttccctctac
    23701 attccattca cttgtaatat ttgaaaattt aaccttaata tcccatcttg catatcccgg
    23761 agtttttaaa gtttcaaaga tgaatttttc aatatcttta atcggtatcc aagtcgcacc
    23821 aagacgcaca ttgatttcac ttgcttctaa ttcctttgga agaactttgg taagctctgc
    23881 tttttgatat tccaaacgat tcatttcata gcttatcagc tctttttctt ttccattctc
    23941 aacaaagcca agatgaggaa gctctcgttc cgtttgtctt aactttgcaa ggtagctgtc
    24001 tacaatggca atcttatctc taatatttcc gcttaggtac tcatcctttg ttacatagcc
    24061 gtacttatat gaattactgc cgtttgcaca agcgaaaggc aaatctccat cttcaaggtt
    24121 aaaggataat ggtctataaa agttttgttc ttctctgatg tttagataaa tttctcctct
    24181 aagttcttct atcaaagttg gtctgtcttt acctgtaagg ctttccatat actcaaaatc
    24241 cacatagcct ttttcagata ccgataagac aagagcttca agggaagtgt ccacatggtc
    24301 tatgactttg gcttttgtaa tggttctctt tgagaaaata tccccctttg ccttgacgtt
    24361 ttcttcttca tcaagaattt caatggaaga tacaagaggg aaattgctat cctcttttaa
    24421 ggctctggta ttgcttaaat tatttataaa gccatgcttc tttgaaaagt tgtcatagac
    24481 ttcattaagc ttttcttgag ctttctttac ctcatcatcg gaatagtcct ctttctgctt
    24541 gtagataaca tctttaaggg cagtattcag ttcaagatag tccttaatct tttccttatt
    24601 cttatccgtt atctctttct tgatgaaaag ggagttttct ctgtaataga cttcatcatc
    24661 aataacggta taggaaaagt ttttgacatc atccgttgca ggaattgaag tgatttcatc
    24721 atctaaaagc tctatttctt cataagttga tcctttggat atttcttcac ttgcttttgt
    24781 cagaagctct tttaagtcgg cattttcttt cggcaggcac gcaagtgtgt ttccaaatct
    24841 tcctgaaact tcacgcattg tgccgagtac ctgctcagga tgatctacaa aatatttgtt
    24901 ataggtaaga ccattttcat cttcagcaag gtgaatccag tcctcatctc tttctctgat
    24961 actgtccctt ttctttagga atataatatc tgaggttact tctgttccgg ctatgccctt
    25021 aaaggtatca tttggaagtc tgattgcccc taaaaactct gctcttgctg caagatagcg
    25081 tcttacactt tcatcctttt tatccattgt tccacttgat gtgataaagg cgataatacc
    25141 gccgtttctg actttatcaa tggatttcgc aaagaaataa tcatggataa ggaagttatt
    25201 tttgttatac tccctgtcat ttaccttata ttctccaaag ggtatattgc cgataaccgc
    25261 atcaaagaag ttattggaaa aggaggtttc ttccagtcct ttaatctgca cttcactttc
    25321 agggtatagt agttttccaa ttcgaccgct taccgagtca agttctatgc cataaaactt
    25381 ggacttattc atttcatcag ggatattgcc tataaagttt ccgatgccca ttgatggttc
    25441 taaaatgttt ccctgtttaa atcccatatc cgaaagcgtc ttatatattc cgtcaattac
    25501 ggttttcggt gtataaaagc tcgttaaagt agattctctt gcagcttcgt attctgcatg
    25561 tgataagttc tcatttagaa aagcccttgc ttctttccac tgaccttcct tgctttcatc
    25621 aaagacttcg gaaagtccgc cccagcctac ataccttgct aaaacttcct gagctgtact
    25681 gtcaagctct ctttgtccgc tctccactct gttaagcatg gaaattgctt caaggttatt
    25741 atttaacctt tcgcttggac ttaacttttc agggagcgtt tcttctgtaa ttttaaagtt
    25801 atgagcttcc gctttcctta tttgagtttc ctcagtagtc tgctctggct gtttatatgt
    25861 caggttttca aataccctct caaggtcgct ttccagacga taaggaatga catcgaagct
    25921 tgttatcatc ccgccaaaat actcggtgtt gtccttcacc gttaccgtat ttaggttctt
    25981 tctcatatca tcaaagcgtg ttatggtatg gtttttgtcc ttgtatttaa cttcatcacc
    26041 gacaataaag ttcggtcttt caagacttat tttattcagc aagtcctcat tatctgtaaa
    26101 gtctacaatc ggaatttgat ggtttccact tcttaccgga tcaagccaca aatcatatct
    26161 tcctgtgatt tcatttttag aaatttctct gactttatat tcttcatgat taaaatagac
    26221 ggtatcgcct gctttaactg caaactcttc taaaaggctg tcctcttttt cattcagttc
    26281 tacttcttct ctttctttga ggtaatcaaa taaggtagct tgaactgtgc cacgctttgt
    26341 agcttcttct gtttcttcag gtgcttcaag ctctacttta tcttcaaagc taagttctcc
    26401 attaaagaca aactgaagct cctgctcatc catttgtttt ataagctcta tatctttaag
    26461 ttctctaaag gtctttggaa aatcctctaa aatgagcctc tgggcattta attctttcag
    26521 ttcctcaagg ttaaaatatc cccattcagg ctctattcca agaacaagtc caaaggcatc
    26581 accgctttcc ctgtcatact ccgtcatata ccaagtccaa tttgaacgaa aaggaataat
    26641 atatgctgca tgaacctgct tatccgctaa atctacatcc tcctgtgcgt aaatctctgg
    26701 cactctttca agaatttcat caggcattag atttccagga tcatttttag aataatattg
    26761 cggttctttt acttcttcta tctctgccgt actttctgtt tccttttcct caaaataaag
    26821 ttttttagaa agcagctcat caatatgctt tgcaacactt gtccaagtaa ggaacacatc
    26881 attacaatca ttcttctgta atttaaaacc ctttgcatcg tgccattcat cacttcccat
    26941 tgcacctgac acaacgtgag aatgtcctcc gattccatat tcatctttta ggaaattggc
    27001 tttttcctgc aaagtatgat tttctttaaa aaacttggtg attcgttctt ttcctctatc
    27061 aacgccgctt cctcttgaaa ggctttcaag gacttcatct tctgtaataa agagctttac
    27121 cttcggaagt tctgtcagat tggtactata ttcctttcgt tgcagctcaa gttcttgcaa
    27181 cttctgataa agactatcta ccttgtgata atgatacctt aatacatttc tgctttcttt
    27241 gtatccttct aaaaacctgc tatattcttt gattgtttct ttcagatatt caggattttt
    27301 taatgcttca gataatcttt tcgtttcttg cggaaagcca ccacctcttt caaaagagtt
    27361 gaaatatcct tgctctattc cttcttcgct taaatcgtgc gttagatacc ataaggattc
    27421 tgaaattcta tccctttcat agtcctgtgc ctctaaaagt tctacatttg tagcaaactc
    27481 acctctgtca agaagttcat ttatcctact tgctgcatca ctccaactta aaatttgtgt
    27541 attatcctct cttgccgatg ttccataagc taaatgaata cctttatccg aataccagga
    27601 agatacttct ctttcatcaa tgtaaaatcc gtttccgcct ttaaaggtat ctttgaggta
    27661 ttctcccaat tcttctatgc tcttgccttt tgaaaactca gcaataacag gaagcctacc
    27721 gccatcatga tttcctccgt taataaggac ggtatctata tccttctcag ttagcggaat
    27781 agtaaggctt atctgtccat aagaattttc gggtaaagaa aaagaagcct tttcagcttc
    27841 tattatccct ttatccgtat tgtcttttaa atctccacta cttccttgat ggtcatttct
    27901 ttgagagctg aaatcatcgc cccatactgc ggattgttct cgtcctctat cttccaagct
    27961 gctatcaact ttggcttctc tgctctcata aactctactg cctgtttctg aatatccatc
    28021 aggtgtcctg tcagcttctt ctccttgtat agatccaaaa gcatctcgaa gtggctctgc
    28081 tcctcgctct gtgaaaggta attcagcctc atcactgcgt aggtcggatt cggatacttc
    28141 cttataaagt ccgtctgttc ctccaagctg tttagcgtat tctccctgat tttttctatt
    28201 atctcgtccg tactctccat ttcggagaac tcgctcgttt tcatttcttt cctgatcatc
    28261 tcgtcgaaat acattttctt ctacctcctc taattcttct ttaattttat tatatcccgc
    28321 ttcttttcct attaaaactt ctttttgaag ctcaagctct ttgctttttt gaatggtttc
    28381 atcaataatc tttccgctaa tatccgatac actttcacca aggctcatta aggatatgct
    28441 gtcaaatctt tgaaaatttt ctcttaaaag ctcataatcc atcggataat ctaacttaaa
    28501 tcttgaagct accgcatagc ttaccgagtc ccttacaaac ttggtaaatg atattctatc
    28561 ctcatccgct actctaagtt cattcattaa ggtatctatt ttttcatcac cgtagagtct
    28621 gcttaaagaa aagatgtttt caagtgtgct ttcactttcc tcatagccct cgctttttat
    28681 catttccttt aagacatctt gatgggcttc tttatcaaat ctccaaagat tgacctcgtt
    28741 gacatccctg ttttttgaaa ctgtctggct tatatcaaag atatagtcca cctttttata
    28801 tgtgccgtaa tcctctaaaa ttggtatccc tttctgccct cgcataaccg ttcggttaaa
    28861 gcgttccctc cagtagtcga acttggcaca ggctgtcgct tcaggatttt tatcatatat
    28921 acttaattga cttctaaaat catacctttg attgtttccg acaactttta ggagctttag
    28981 atattctgct tcattataca aaacatcttg ttttattagc tccaaaatgt tatgaaaatc
    29041 atttattcgc atttttacct ccttcttttt tcaaacaaaa aaggcggtta gattttactc
    29101 taatcacctt cgctatatac caaatattat tactctattt caatttttta attgattcac
    29161 tttcagatag tatcttcatt tgttcaatag ctattgcatt taatttttcc aatctttcag
    29221 attggctcat gccttcattt ataaataccg cattaagatt ctcaagatta gaaaggcaga
    29281 caagctgtga tatatccgca taatctctaa tattgccttt taaatccgga ttttcatcac
    29341 gccactcctt agctgttatt ccaaatagag aaacattaag aatatccgct tcacttgcat
    29401 aaataaaatt gattttttct tttgaaagtt tatccggtac aagtttgttt ttaatggcat
    29461 ctgtgtgaat tctataattg atttttgcca aatttctctt aatatcccat cctaacttct
    29521 tttgttcttc ttcctttagg cgttcaaatt ccttgattaa atataattta aagtatggcg
    29581 atacccaaga agcaaactca aacgctatat ctttatgagc ataagttcca ccatatcttc
    29641 ctgctctcgc aacgataccg atagaattag ttttttccac ccattgcttg accgataata
    29701 taaaacggtt aaatcctgct tcatttttaa ttccctcgaa ttcgggggaa ttaaaattcg
    29761 tgttatacat ttcttcccaa atacctaaaa actctattgt attcttgttt ctgagccact
    29821 tttcaatcaa agcagaaccg ttctcaatat ttctaaccat atccgttaaa gaaatataat
    29881 ctctattgtc tatggcaata atgctgattt ctgaaccttc aacatttatt ttagacatat
    29941 aatcacctct caatcattaa attgattact ttgcattata gcatttttag agcatttttt
    30001 ccacgctgaa attagtgctg tcttacttgc gatatgtcaa aaccgcttct tttatctcat
    30061 tttcaatcgc atctaaaaat tctttcttag aggatttacc ctgagcaata tcagataatt
    30121 ccatttccca ctttgctgtc gtttctgccg acttaaaggt atctgctaca atcgttacaa
    30181 ggctgattcc tttatgcgtt gcaattagat tcttcttatc tctttcgaca aatctcttaa
    30241 agattagatt ttcaataatt cctgcccttg ttgccggagt gccaagacct tttctttcca
    30301 cctctacacc tttttctaag gcatcatttc ccgcaatctc catagacttt aagagcgtat
    30361 cttcagtaaa gtgtttcgga ggttgggtaa atttttcttt aacctcttta ttttcaacgc
    30421 tcaaaacatc accaacactt acatcgggca atacagcatc ttcactcttt tttgatttgt
    30481 attctttaag gtatttgcta aagccttcat ccttaattac cttacctgaa cttgtaaatt
    30541 caaaaccgtc aaatgaagct acaatctttg ttgtattttc aataagcgga tagcctacac
    30601 ttgcatgaaa tttatcggat ataaggaagt aaacttttgc ttcacttaaa ggtaattcag
    30661 aaacatcttc ttttactgaa ctgattgtcg gtatgattgc atgatggtcc gtaacctttt
    30721 tagagttaaa tactaccttg atacgctctg tatcaaagtc atttttaccc aaaatgttgt
    30781 tgactgtact cacaatcata tcctctgtta aacatctgct gtctgttctg gggtaagtaa
    30841 tcagtttctt ttcatacagg ctttgagtat agtcaagtgt ctgcttggca ctatatccaa
    30901 aatatttatt gcactccctt tgaagcgtag ttaggtcaaa aggtaaatca ggctttgtaa
    30961 ttttttcttt ttgaataaca tcagtaattt caatcttatc gcctactaaa cttataagct
    31021 gttcagcagc aacttcatca tcaattctgt ctgtggagag tgtaaatcca ttcatagaaa
    31081 gctctactgt gtaatatttt tctttctgat aatttgctat ctcatcatct ctttttacaa
    31141 tcatggcaag ggtaggtgtc tgcactctgc caacactgta attttgctga tacagacaag
    31201 agtagagcct actaatattc attccgacta accaatccgc aatagctctt gcctgtgccg
    31261 attcaaagag attatcatag tcttttccgt ctgttaggtt atcaaaaccc tctttaatgg
    31321 cactatcttc cattgaagaa atccaaaggc gtttcatctt ctttttacaa ttcacttgat
    31381 tatatacaag tctaaaaata ctttctccct cacgccctgc atcgcacgca ttgataaccg
    31441 tatcaacctc cttatcattc atcagctttt taaggatgtt aaactgcttc ttggttgcct
    31501 ttgctacttc atacttgtag tcgctcggaa taatcggtaa atcagccata ttccacttgg
    31561 cgtacttttc atcataagca tccggatttg ccatttgaat taggtgtcca acgcaccagc
    31621 tcaccctata tccgtttcct tcataatatc cgtctttctt tttatttgct ccaataacct
    31681 ttgcaatgga gattgcaaca ctcggctttt ctgcaataac taacttcatc tgtgttttcc
    31741 tcctgttata aatcaaaata gggcgaaaga tgttactctc ccgccctaac tttgcaccca
    31801 aaataatatg tttttaggtg cgtttattct tcatcttcta cttcatctgc atcatttatt
    31861 tcttcctcgc tttcagattc agaaaagaaa tcatcatctt cctcctctaa ggcttcaagt
    31921 tctttatctt ctttcttttt cacaacctta aaatagtagc ctgctcctaa tgcaccacct
    31981 actacaagaa gcaaaataat ataggttcct aaattactct tttcgtcctt cttctcaggc
    32041 tttacttctt ccttaacagg ttcttctttt actacttcct gctttggtgc ttcttttttc
    32101 tccaccatgt taagcaaatc atcttcagat acttccgtaa gaagcattac attctcacta
    32161 tcttcatcat gattgatgat taaatgaaaa gtcttaccgt ttttcgtttg aaaggtaata
    32221 aactgccttg catctgccga atactgatcc gtttctttgt tatcgctgct atctccatga
    32281 tgaatcggat actccttatt tgcattatct ttattctccg taacggatgc tctcgccttt
    32341 gacggagatg aagctactcc cttgttggtg tttacactct tacttgcaga ccccattgat
    32401 gaatcctgac tgttattcgc aggagctttt gccgtcaact tattgggata gcgaacttcc
    32461 ttttctttct cctttacttc cgttttgcct ttaccggtat cctttgtagt attacctgag
    32521 cttaccgaat ccgatgagcc tttaccggta ctacttacag aagtctgtgg tgtttgagga
    32581 gaaatacctg aacttgtctt aattccggaa ataggactaa tcggtgtaac tgattgtgat
    32641 gttacaggag ctttatttgt ttcagttgcc tttttctcaa gctctttcac cttttccgtc
    32701 agcttatcta tttccttttt catatcttct gataagtcct tatttccctt atctttcttc
    32761 attttttctt tcaggctatc aatttcatct tcaaggtctt taattttatt cttttgctta
    32821 tcacttaatt tgtctttgtc cttaagttcg caatttaact tatcaagttt atcctgaagc
    32881 tcttttgcct ctttttctat ttttgaaata tcgtctttag aaagctctgt ctgcgttccc
    32941 ttatcttctg tctgagtgca ttcatcctgc tttggctttt cttcttccgt ctgcgtttcc
    33001 ttatccttaa cctccatctt tgctacctta cggataatct catcttttcc atctcccttt
    33061 acctcataaa acagaaattc atcaatgaat ttcatatcat ctgggagcat tggaagatct
    33121 ccgctatcaa taagttgtcc tttctcagcc tttatctttt cttccttaaa gaccttttca
    33181 tcttcaaaga tataccttac atttacttca acttccgttt gaacagcttc gttttttgtt
    33241 ggagcttcag atttttgctc ctgtgcataa acaaccgtcc aaagacctaa aatacaacta
    33301 atacttacaa ttaccgcaag tgctaccgtc caaaacttat tattcttttt caaactggtt
    33361 ttcatttgtt ttctcctttt tcatttctgc tttttgtctg tttacctttg ctatcaaatc
    33421 gctgattgtg atgttgttct ttctgcaaat ggcaatgatt tcttcatttt caagctcttc
    33481 ttcacgaatg aataaaggct ccaattcttc atcaatcaga gcctttttat cctttaactt
    33541 ctttattctg ttttttactg ttgtaagttc ctttttcaaa ttgttacctc ctatttcttt
    33601 acatttggcg gaaaaccgaa tcctacggga tggtgcttac aaaatgttgc tatccaatca
    33661 tctaaggtag ttactcttat tcgaccgatg ttatcaatca cttttccatc tccaatgtaa
    33721 atacctacat gaccataggt aagccctgca ctgcttccgc tactgctgct ttcaactgcc
    33781 acaagcattc ccacttttag ctttgacctg tctgatgtaa aggtatagtt tcggtacata
    33841 tcacaggcat tcccgcctat atatccaagt cctgcatttt gatagacctg tgatacccac
    33901 atggcacacc agcctgcacc cggagatggc gtaatgtatg cagcattaac aatcttcttt
    33961 tgtacttccg tagatgcctc atactctttt ccaccgccga tacctccatt tgcactgata
    34021 aggtcagaat taccaaaggc ttctctcata ttgccttgtg caaggaacaa ggcttcatag
    34081 tgctttagat tatcgggata gtttgcaaag acctttcgga taatactgtc catctctttt
    34141 ttatgaagcg ttacgatgag ttttttatac tcataaggtt cttcgtggct ttcggtatat
    34201 tcattgccat cttcatcggt ataggtttcc gtaaccgtcc tgtatctgat ttcaatttct
    34261 tccctatact caaggtcata catggactca aataattctt ttaatatgga ttctacttcc
    34321 gatacactct ttacctctcc gcaccttgat gtaatgtagg ataaaagctc atggacatta
    34381 tgaccgatgt attctgtatt atttaagata tattcatcat atccaggata attttctttc
    34441 acatagtcaa cttcactttg aagctcaccc tccatatctg aaaatttctg attgatttca
    34501 cttaggacat ttggctttga taaatagctt gttgtaagca cagagcttgt agagttcata
    34561 aagcctgtca ttcccgttcc tgcaaagtta atcacaaaag tccctaagat aatgatacct
    34621 atgaaaataa gcattagtcc ttttgctttt cggataatca tatcctttga gcttttcagt
    34681 gttccgataa gtccctcttt aattcgatct ctaagccttg acttattctc acgagaaatt
    34741 gctgccttta cctgattttt cttttgaaat cttttatatg cacttgctct tttatactca
    34801 tccgtctttt tcagttcctt tttggcatca cgaaattcca actttgactt acgctttctg
    34861 attttatagt ccttatttgt aaggtcatag cctcttttag ctcttttctt atcagagtac
    34921 ttctttatgc catgaatgag cttggagctt gtatctgctg tcttttctcc tgcttccact
    34981 ccttgatttt catcacttcc atgagacaag taatctctta cagtttcact tcctttagca
    35041 agtcctgaaa gggcagatac ctttaccatg tcttttttta gctttttctt ttggtctttt
    35101 gataggctgc tataaacttt tccgctgaca gcatcttttc ccgccttttt atcatcagcc
    35161 ttatttccct ttggtgcatc gtcctttttc cttgtataaa ggctttcaga atagttcttc
    35221 ctcttgtacc tgcttttttg agtcttatga tttttaaagg aattttctaa tgatttttct
    35281 ttatgggaaa gattatcctc cacatcatag gtcgattcaa aatagttgct gtctctaaag
    35341 tcattatcgt atctgtctat aatcccgtca ttatcaaggt cttttcctaa aggatcatag
    35401 atttttccat ccttaacctc cgtaatataa tctgatcttc ccgtttcaat tgcggaattt
    35461 acgtctccct tatctgaagt tctatatttt tcgtttctct tggatgttcc ataagacttt
    35521 tcattatcag cacttacctt acttgttttt tcatgcactt tatcctgaaa ccgttctttc
    35581 tcatgaacga ttttacctct gtaatcatcg ttatgtttta gcttactttc ttcaggtatc
    35641 gtatctgttt tactatgaaa catctctctt tcaaggcttg ccttatgcct ttccttaaaa
    35701 tcctttttca gcttctttcc cataggctac ctcacttctt ccggcttggt agtcatcttc
    35761 tgatataaaa ttgtatcttt cggaaactta tcaatgaaag gcacaatggt atttccaaag
    35821 aataagagtc cctcaccttc atttgaatta gtaacatatc tgagctgtgg aagtgagatt
    35881 ttaagttttc ttgcaagtat ctccctatct cctgatgctt gattaagcat taagacaaag
    35941 tctgtattgt caaagatatt ttctatctcc ttactcataa gtaggtcttt gacattctgc
    36001 gtaatacctg ttggaatacc tccccattta cgaaatcttt tccaaatctc tacggaatag
    36061 gatgctgtct gctcatcttt taaaagcaaa tggaactcgt cgatatagta ccttgtagcc
    36121 ttgtttcctc tgttttgtga caccttattc cacacctgat cctgaataac aagcataccg
    36181 attttcttta attgacttcc aagctcctta atatcaaaac aaaggagctt cttatttaaa
    36241 tccacatttg acctgtgatt aaagacattg agagaccccg atacatagat ttccatctct
    36301 gttgccagct tcttaccgac cttttcttcc tgccctttta acatatcgta taggtcttga
    36361 agtatcggca tattgtcagg agtaggatgt tcaaaatact tttcatagat tttaggaagg
    36421 cacctatcta taacggactt ttcttctgct gtaagaccac taccgcctac tacaagctca
    36481 agcatactca tgataaagtt tgccttgtct ttcagcggtg catccccatc accgtagttc
    36541 atgtttatat caagaggatt caggtaatcc ttcgacttac tgctgacctt aatgacttct
    36601 cccttaaact gccttacgag gtttccatac tctccttccg gatcgcagat aatcacatca
    36661 tcatctgtta ctaaaatcgc atttgccatt tctcttttgg cactaaagga cttaccgctg
    36721 cccggagttc cgaggattag accgtttggg ttctttaatt tctttctatc tgccataatc
    36781 aggttatggc ttagggcatt tagtccgtag taaagactat tacttgaatt gataaaaagc
    36841 tcctctgtgg taaatggcat aaatactgcc gttgatgagc ttgtcaatcc tctatctatt
    36901 tcaatcttat ttacaccaag aggcagcacg ctcactaaac cttgttcctg agaatggtca
    36961 agtcttttca gcttacagtt atgcttattt gcaatggagc ttatttgagc aattgtgtta
    37021 tcgagctttt gcactgtcct tgcaaagttc ataaagacga tacttaccac aaacattcgc
    37081 tcatctcttg tctgcaagtc ttttaagagg ctctttacat cctcaccata ggtaattaag
    37141 tccgatggaa gaatgtccat atcataaccg cttcttaccg ccttcttatt ttcctcaatt
    37201 ttcatcttat caatatcagt gttttttcgt tttaccatct taatggcttc cgattggtcg
    37261 attgccctaa tatgaaagga aatattgatg ttatcgtcaa tatccaaaaa ctcggataac
    37321 atcctatctg aaagctcact ggcaaggatt tgaaaatgac ttgttgctcc gatgaatttg
    37381 ccgaacttaa agtatctact cggtgtaaag ttaaactcat caggcacaat atatgtcttt
    37441 gtgctttccc ttttctttag gtctttgtag gaaaatttaa atgttttatt tggatttaaa
    37501 acatcatgaa gtatctttag cctttcttct ccgtttaggc tttctgctct tactcccata
    37561 cttttaagac tcgataatat atctatctcc agtctttcaa gttttgatgt tgcctgttct
    37621 aaattatccg cttccactgt aaaggttaca tactttgatt ttttcaatcc gttatttccc
    37681 tttacaatct ggcttttaag catctctcta aattcaaagc gtatatcgtc gaaaccgtcc
    37741 tttttatccg gtatctgaat tgccgacttc atttcttcgt ttcgtccgag ctgattgata
    37801 tatgaaaact caatgctgat acttggatca aaagagttta ggaagtttgc aaattgatta
    37861 aaaatcaagt ccctatcttc atctaaggca agctgatagt taatgtcctg aaaggctata
    37921 cttttactga agtgcttttc atcaagctgg catattccgc tttttaaaag ccttagatag
    37981 ggaatggtat cttctaccgt atatcttttc ggttctttct taaagataag gtcaaggatt
    38041 cctcccttat ctttttttga cttgcaatta cttttcttta agtcccgctt ttgacttctc
    38101 aatgcctttt cgttttgcat gagttttatt tgctgaattt ttcttttctt gttcaaggta
    38161 aacctccttt ctcactctct tttgcggttg ataaaactta tgaagataaa tgtacttaaa
    38221 gtatttctca aatgtcagtc cgtctttttc aaatagtgtg atgaaaaaga taggaagcgt
    38281 ggatacgata aggaatatga cagctatgtc atttggcaca aacttcctca taaataaata
    38341 gactggtatt ccaaccagtc ctgcaagtgt gaagcctatg agctgccttt tcgttaggtt
    38401 aaaagcaacc tttgtcttta ccctatttaa gtctttaggg attggtacat atgccatatc
    38461 ttacctccca tcttctttac cctttgacag ctcctcaaag tgttcatata cagagccgat
    38521 ttcttcctga atagtcgcaa gctgttcgtc tgtgttcttg ttatatcttt gctgtattag
    38581 gtaaaaatcg ttatggcagc gaccaatgtc ctctgttttt tcttccaatt cttccacctt
    38641 attatgaagc ctgatcctat caattatcgc cataatacct gctccaatta ctactataaa
    38701 tactgttttt cttttgttca tattaccctt cctttctttt agtgtgcatt taatacgctt
    38761 ttggccagtg ttccgctctt taacatcatt aaccctagca aaaccgcata tccaagtatc
    38821 gtaaaggtac ttgtgtgtat atctgttatc tgtattgtct taactaatac tgcgtatatt
    38881 ccaagacaaa ccattaaaaa gagtccttgt aaacctatgg caaacaatcc tttgatatag
    38941 tttgttccaa tctgtcccca ctctttgttt cccattgtgg caaatggaat ggctgaaatg
    39001 gatgagtaaa cataaatctc aaacattctt ccgtaaacca caagcataat cacaattgaa
    39061 atgacctgta ttgccacctt tataagcgag gtttcaaaga gtatcatgac aagctctcca
    39121 agacctttat cctttaatcc atctaccatt tttactatct gatctccgga gataacggca
    39181 gaagtattga ttacccctgc cgctttattt accatgtgct gtgccacatc aaagaccgcc
    39241 attgaaaact caaatgcatg tgatactaac catacagcaa tccacatctt gatgatgtac
    39301 ttgaaaaatt caaaagtatc tgtatcgtgc atattgttct tttgcattac catattgata
    39361 agctcgatac aaaggactgc tgtgatgatt agccctgcta tgggaataat gacggaatcg
    39421 ttaatgcttt taataaaggc aaatacatct ccgttccacc ccataggagt ttttcctaca
    39481 tctgttgcaa ctgcaccaac tttatcgttg atgtcaagaa acatggactc taagtttgct
    39541 tgaataccgc ccagtagaag ctctttaaag aattcttcta tcttgtcgaa tattccaaac
    39601 atctaagctc tccttttctt attacttgag tacatttgca agaagcggaa tcagcttaag
    39661 tccgataagg acaatgcctc ctcccgccat aagctgtttt atccccaatt aggtgtaaaa
    39721 ctctgctcga tggcgggcgg cggcgtacaa aaaatctata tggtgttttt aagagaaccg
    39781 tcccggcggg acaggtcagg cagtgacctg ttccacctct gggatgggtt tgagattaaa
    39841 atgaatttcg atagaaatgt gtcttgtttt atcttcgtca atgcgctcat gcacgacgat
    39901 ttctttgatt aagcggttga gggtggctgc gtccagctct gtgatattgg cgtattcctg
    39961 aatggcttcc acccattgtt ttgcgtcatt ggcaagctgg acttcatcgg acagccgctt
    40021 tctgccctcg gacacttttg ctttaagctc cgcttgctcg gtctgtgtct tttccagcat
    40081 ggtgttgaaa ttctgttcac tgatacgccc tgcaatcata tcctcataaa gccgcattac
    40141 cattttgtcc agaacctcaa tccgttcctc gtcccttgtg agggagcgtt ccattgcttc
    40201 ccgctgttcc cgctgctcgg cttcacaggt attggtcaag cggtcggcaa ccgcttcccc
    40261 gtccatcagg gcggctctgg cacattcccg gattttccgc agcacatggc tgtaaagggt
    40321 gtcataatca atccggtgct gggtgcagtg gttctttcca aaggcattgt aggtcttgca
    40381 ggaataaatc tgctgaggat gttttgcgtt tgtgtagcgt accgtcagcg acttcccaca
    40441 ctcgccgcat tttatcagtc cggcaaacag gctgatttca ttggtctgcc ccggacgctg
    40501 gcgggatttc agcttattct gcacaatgtc aaagctcatg cggtcaatca gcggttcatg
    40561 ctgcccctcc accacaatcc agtcctccgg cttcttttcc ccaatcgtgc cgattttgaa
    40621 acggtagtcc tttttctggg aagcaatcgc cccggtgtag acgggattca tcaaaaggtc
    40681 tttgatgacg gagaagtccc acatataccg tcctttttct gggtctttct tttcccattt
    40741 ggtgcgggta ttgcgaagcc cccgttcccg gttccaccat gtggggcagg ggattttttc
    40801 ttcctccagc cgtctgcgga tatagttcgg accatgaccg ttcagggcat atccgaaaat
    40861 cagtcgcaca atcggggcgg tttcctcgtc aatgagcaga tggtttttgt cctccgggtc
    40921 tttccgatac ccaaacgggg caagacaccc ggtaaactgt cctttctgcg ctttcagaag
    40981 ataagaggaa tggactttct tggaaatatc cttgctgtac atctcgttca ggatattctt
    41041 gaacggggca atatcgttgt tatcacgcag ggtgtcgata ccgtcattca tggcgatata
    41101 gcggacaccg tttcttggga aaaagtcctc aatcaaatgc ccggtttgca gatagttacg
    41161 ccccagtcgg ctgaggtctt tcgtgatgac aaggttgatt tgcctgcgct caatggctct
    41221 caacattctc tgtaaatcag gacgctccat attaagacct gtgaagccat cgtcctgata
    41281 gactgccaca acctcccatc cctgcttttc gcagtatttt tccagcatat cacgctggtt
    41341 tgcgatactg gcactttcgc cttgcaggtc atcgtccttt gacagtctgc aatagaccgc
    41401 tgcacgataa cccccggcaa gtgccgaacc gattgttctg tattccattt cgttcatcat
    41461 agccatttac ccacacaatc cagacggtat ctggctcttt tgaacctcat cttcattata
    41521 cttcaaatct ttctttttag caagatattc tttcgtattt gtcttaccgt atttctggga
    41581 aatcaggctg acgaacacat cggttgcgtc cagctccccg tcaaacaccg ttgtaacatg
    41641 aatctctgtt ttgttttttg ccataggcag ttatcctcca tacatgaaaa tagccagaca
    41701 gagggtgtcg gcaacgaagt ccggcaacgg gcttcaaaag accttgcaaa caatctcaat
    41761 ctggcgatgg ttactattta tacttttctt ttatttttct gttgttttgg ttgtcatagg
    41821 ggagaaaagc ccagaaataa gggattttcc ccggcaaccg gctcggcaac gggatagcaa
    41881 cagggggtgc aacgggctgt cattttcaga atggaagctc catctgttct gagacctcca
    41941 caaaaccgtc cctcgttttt tcagacgggt tgcataagtc cgttgccggg ttttcacgct
    42001 cccagccctt ttgtctgcca tattcggaaa acattcttgg gttcgggaag taccgccagc
    42061 cagaaatgca ctggttcata atctcgttga tttcccggat ttcccattgc ttcggctcgt
    42121 caaaggcatg gttcaaggct tccttataga gctgcttgga gcagaccatg ctcccggtgt
    42181 acttatcaag atacgcctgt atcatcccgg ctttggtgtc ctccggcata aaatcccgct
    42241 ggtgttcttt gagataccgc tgcatggcag ggctgaaagc cagcttgaac ctgccgcttc
    42301 tgtaaatttc catcgcttct gcccacatct gctcgatata ggctctggaa gcggcttcgt
    42361 cctccaaaat gtgaacctcg gcttgctccg ggtacaccat gacggggata aagcggcggt
    42421 tgccggaacg gtcaaggggc aggaagtcaa gggcattgga agtgccgcca aacacgcact
    42481 gacgggggcg gtctgctggg tgggtttcat agggtatctt gtaaacctct ttctgtcggc
    42541 ttaaaaatga cttgatttcc tcaatgctct tggcgttggc ggttgccatc atttccgaca
    42601 tttcgataat ccagtgacct tgcagcttgc ggtacacatt gtcatcgtcc aacttccgca
    42661 aatcatcgga gaaccactcg tcccggactg ccagcagacg gaagaaggtg gacttgccag
    42721 ccccctgacc gcctaccaga cagagcatga tttcaaattt gcatcccggc tgaaaggctc
    42781 gtgagattgc gcccagcagg aacagcttca acgcttcata ggtgtaatcg tctgcgtcag
    42841 cccccagaaa gtgccgcagg cagaaacgga ttcgttctgt cccgtcccac acaagggtat
    42901 tgagatagtc ccggatggga tggtacttgt tttcattcgc cacaatcccg atggcgttat
    42961 caatcttctt ctcattggta agcccgtagg tttcttccag atagagaagc agatacttca
    43021 tgtccgtatc gttcagggcg gtgctttccc tgtggaagcc gatgggcttt atgatgtcct
    43081 tgcggtcggt caggatgttg tatgcgatag ccccggaaag cagcgggtca cgctggaata
    43141 cggtcaggca gttccgtatg ctctgacgga caccgccttt ctcggtagtt cccagccccg
    43201 ccttgatttc ctcaatgctc tggggcggct gcatggcgtt catggtgttt tttagttctt
    43261 gctgcgtttg cggcggcaag ctctgccatt cgcttttcaa gctgtatcac atcctttccg
    43321 tagtccgtaa tcaaagctgc tttttcctct gtctccccaa agagcagcac atccagcaga
    43381 tattccactt ggtcttgctt ctgtaaggct tccacaaacc gtggatgaaa ggcttcctcc
    43441 ggggagtgcg gggcataatc ctttctccat gcccgaagca agtgaagata atcggcaaga
    43501 atacggaagc agcggttttt tgcttcctga aactgttcct ccggggattt ctgccggggc
    43561 ttgggctttt ttaccttccc cggcggtttc cagtcctcat aggaaagccc gaagtcctgt
    43621 gccagctgta cggcggcttc tttctttccc agcccataca gggcggcggc aaaatcaatc
    43681 acatccccat ccgcaccgca gccgaagcag tggtaacgcc gatccagctt catgcttggg
    43741 gttttatcgt gatggaacgg gcaacaagcc atcccgttcc ggcctacacg gattccataa
    43801 tgctccgcag cctgtcttgt tgtgacggac tgcttcacag cttcaaatac attcaaatct
    43861 atccctcctt gaaaaaaaga aaagcacctg acattctctg attgaaaatg gcaagtgcct
    43921 gttaaagttc catatcctgt tgtttgtgtt ttgtctgctc cggggcagtt ctttgtgctt
    43981 ttttctcgtc tgtcttatcc tgcaagactt ccttgatggg ctgcttcttg ggcggctctt
    44041 tgctttcctc tgtgccgggt gtggctttcc gtacccagta gcggatgtcc cgcagcttct
    44101 tcaaatcctc ctgtacctcg gtcagcggtg ttttcagagc tgcaatttct tccagaagcg
    44161 tttcctgctc ctcttgcagc tccttttggg tgctgtcctt atcgtccggg tgcttggcaa
    44221 ggtaggcggc ggctttctca taccgggcaa cctccgggtg ttcctgtttg aatttctcct
    44281 ttgttttttt gaaaaatatc ttctggtatt tctcatagac aggcttacat tcctggcagt
    44341 ctgtccggct ggcaagaatc ccgtcaatca ctttgctgcg ggtttccttt ggcttcatct
    44401 gattgcggta atcggcggct gatttcccgg aagattccag aaatacttct aagtcctcca
    44461 cagtggaaag ccccttttgc cggagatagg acagggcttc gctgactgcc tttaagtcct
    44521 gtgaagtccc ccggttctgt ccagcccttg tccagtcctt ccgttcttcc tttcgtatct
    44581 ccatatactt catcagcaga ttgggaagaa gtgtcgcttc ctccgccgcc ttttgtgcaa
    44641 gcagttcttt tcgtttttct cccagctcgg taatccagcc tttgaggttt tgaatgagct
    44701 gccggataga cttcatcagg cggttggcgg ctctgatgtc ccggttcagg ttgccgatgt
    44761 tcgtctggat accccgcttt tccatctgcc ggacagcagt cccctcatgg acagtgggga
    44821 ctatatcaag cccctgtctg gcataggaac gcaagtccac acgctctggg cggtcattgg
    44881 cttccagata gcggttctgg atgacctccc attcatgccg ccagatttcg caatacttct
    44941 ggtcgttcca atccaccgta tcctccttgt ggcttttcca tctgccggac ggaagtttta
    45001 tccgttcccc gttttcgtca aggtcataaa ccttgcggct cttgggaagc cattttccat
    45061 gttcgtccat tgccctcata gtgagcatga catgggcgtg gggattgtgt cccggcggat
    45121 gggggtcatg gattgcaaaa tcagcaatca tgcctttgga aacaaactgc tgctcacaaa
    45181 actcccggac aatgacagca tactggtcgg gtggtatctc tcttgggatg gtaagcaccc
    45241 acctccttgc aagctgggag ttccattgtt tttccacagc ttcggcggcg ttccataagg
    45301 tattacggtc tgcatactcc ggcggggcat ttgctgggag cagaatctca ttgtggacga
    45361 taccacgctt ttccgggtag tgcttcactt gctggtcgta ttcacagaac agcttttcgc
    45421 cactctggta agcagcggcg gcaaccgcag actgccgctg gctgcgctga acaatcgtga
    45481 tttcgttgtg tggacagggc atttcgtgtc cctcctttcg ctaattggtg gacggggtgg
    45541 cgttttacca cctcattttg ggcagaaaaa aagcaggaga cctttttcag atttcctgct
    45601 cggtgtgccg ctatgtgggc ggcgggtatt taattgtaaa agttcggggc aagttgaccc
    45661 gatgtgaagc tgacaaactg gaagttattt tacttgcgtt ctataaatcc tatgattgaa
    45721 aaaatcaatc ctacaatccc aattccgata acgagcagcc ccattcctga tgagcaaaga
    45781 gaaattataa tggcaaagag tagtatcgca atacctaatc caattttctt cattgtaaat
    45841 cctcctttac aaatgccgat ttgttgtcat cttcattata cttcattggc tatcgaaaag
    45901 atagcatatt ttatgaaact tgtcggctgg gaacagcttg caacgcaagg tgtccccaga
    45961 tggcaagtac acaaaagggt agctggcggc agccagcgca ggggaagcgt agcgtcccct
    46021 gtatgatttg gagcagacca tgactgcgga aaattacagc cctccggcga ggagccttcg
    46081 gagaacgcaa tgcaccaacc tctgggtggt gtataattgc gcccttagta aactaagggg
    46141 tttccggctt cttccgttcc agcagttttt tcaatagttc ctgcgtgtcc tgcctgtgaa
    46201 aaatgagttt caataacagc atgacatcat catctgtcag gcgttccggc tcttgcagaa
    46261 aactttccag cataccgcca cgggtacaga gccggtgcgt ccgttccttt cgggtaagct
    46321 gcttcaactg gtgctgcaat accttttcat cattaatggc tttccgcagc ttcttttcgc
    46381 ttttctccag ctccctgttg agcttttcca gctttgaggt atcaggcaag ggcagcgtcc
    46441 tcctttcccg gtatcagcac ataaatcctg tttggttctc caacgccctg acgcacccgc
    46501 atgataagtc cggcggtttc cagttcattc agagaacgct tgaccgtcat gggactgcgg
    46561 gacaggactg cggcaatggc tgtgacaggg aagcagacaa acaggattcc gttctcgtcc
    46621 tcctgccctt tggacagcat agcgtccagc atccggcagt acatgacctt tgcggtgctg
    46681 ctgactggaa atcctgtcaa cgctctggga aagggcatac agggcggcaa gggtgtgtct
    46741 atcgtcataa attcaaaatt cattcggtgt gtgcctcctt tttctttgct cgtttggata
    46801 aataacgggg gcagtcaatc acaaccgccc ggaagctctg cctgcaccca tgctggcatt
    46861 tccggcataa ttcgttgtaa gtgacacgcc cccggtcatt gaggtaaaag gaaagctcat
    46921 atttcctctt tttactcatt ctcggcatat tgtgtttcct cccgttttag tgtatggttt
    46981 cggggcgatt ttcggcaaaa ttacagccat agagccgcct aaaatctccc gaagtatcag
    47041 cgatagggta ggctatcccc ctatcagatt gtcgtgtttc ggtatcattt cggtgtcagt
    47101 tcgccagttc tccccggtgt cgttcctccc ctgaatctca cagcggcgta tcgctccctt
    47161 tggtacgctc gtttcggtca gggttcctcc acatccctgc caaaagtcat ggcactacat
    47221 cgccggggaa gcatatccca cacaggctgg tcattcgatt ggaataatcc atcgatgaac
    47281 tacctgtatc atagaacatt tttgtgccct gtgccgtatg tccacaaagt aggaattagg
    47341 agtaaaaatc agaaatttcc acgattgcgg aaagtgtgat ataatccagt taagcggcag
    47401 caatgaaacc gccggaaagg agtgtgcgcc catgaaagga gcaacaagca tacaggaacg
    47461 cctttgggaa ctccgcaagg acaaaggctt aaatctggaa gaactatcaa agctgacggg
    47521 tatttccaaa tctgctctcg gaagttatga aaaagaggat tttaaggaaa tcaatcatgg
    47581 caaccttatc acgctggcag acttctatgg ggtttccgtt gattatctac tgtgccggac
    47641 agagaacagg gagcagatca acacgtcatt gacggagctg catttgaatg atgagatggt
    47701 tgctctcctg aaaagcggtc ggattaacaa ccgtctgctc tgtgagcttg ccacacataa
    47761 agattttatc aagtttcttg cagacattga gatttatgtg gacgggattg ccaccatgca
    47821 gattcaaaat ctcaatgcac ttgtcgatac cgtccggcat gaaatcattg aacggtatcg
    47881 ccccggcgaa gatgacccgc atttgaaagt gctgcaagcc gcccatatca gcgatgatga
    47941 atatttcagc cacatggttc tggatgacct caatctcatt atccgggata ttcgggaaac
    48001 tcacaaaaag gacagtgaga gtgcgcccca gaccaccgtt gccgatgaac tgaaagaaaa
    48061 tctggaagcg gtcgaaaatt tcaagggcag tcgggatgaa aagctggtca tcctttattg
    48121 caagcagctc ggtatcaact ataaaaatct gtcggaagaa gaattccgct ggctcattcg
    48181 gattctcaaa aaatcaaaga aaatgggaac gcctatcagc caaaggaaaa aacggtaaag
    48241 aaaaaccgct gttgcatggt ttgttagctt ccatgtagca gcggttttta ctgtggttat
    48301 tcagttgaaa atcagaacga taaactggaa gttatcgatt tctttgtgcg ctgtatctaa
    48361 cggacagcac aatgcttact gatgcggtaa tgacctttgc aaatacggcg ctccaccaaa
    48421 tcgtgatttg accgccaaac accggcggca gcatcagcat caacaccagc atgatgatgg
    48481 gttcgataaa ggtcagaaca taggacagca cacttttttc ggttgcgtag aaagccgccg
    48541 cggaaactcg tgtgatggcg tcaaacggaa ccgacacaag gaagatcggc atgaccttta
    48601 tgacccctgc gtttacctcg gcagatgaac cgaacagtag tccaatcttt ccacggagca
    48661 ggtaaatcag aatcgcactg attaccgcca aaaccatgga aaattcatac gccagcgttt
    48721 tggtttgttt gagcgatttt tcttcgcctg ctccgtagaa ctgactcatg agcggctggc
    48781 taccatcacc gacaccctgc aaaagaagat aaacaatgca gatgatatag gagatacagg
    48841 cataggtggc gatagcctcc tgtccgccat aataaaccga aaatcggttg atgatcacaa
    48901 gagagatatt tggggcaagg gtcaagccaa atggagcaag tccgattttt aatatctgaa
    48961 atgccgtttt cggggtatca acaggtgcga ttttcagagt gaggttcttt ttgatggcgc
    49021 aatacacgag tgcaaccgcc atggtaactc cctgcccaat aatggtcgcc aatgccgcac
    49081 cgtacatgcc ccgtccaaga acccacacaa aagtatagtc aagagcaata ttggtagcaa
    49141 agccgcagat catagcgatc attgcccaca aagaaccgcc gtaattacgc ataaacggaa
    49201 ccagtccggt gccgaacacc tgtaaaatcg ctccaagggc aattaccttg atatactcat
    49261 ttcccagagt aagcaactcg cccgatgcac caagggcaga aaggattttc tctgaagtga
    49321 agaaaacggt gacagtcagg acagcgctga aaagaagcat cagccatgtt gcaccggcaa
    49381 cgaactcccg tgcttttttc tcatttcctg ctgctttcag aatggagtat ttgactgaac
    49441 cgcccattcc gattcctgtc cctacggatt gcaggaccgc cgtgatggga tatgcaatgt
    49501 tgattgcgga aagtccggca tccccgattg agttgcctac aaagaaaccg tcaacgatgg
    49561 catacacccc ggaaagcgca aaggataaca cggacggaat cacatactga aagaaagtcc
    49621 gcttgttatt cactgcccag acctcctctc agctctcttt caaagagaag attgaaaagg
    49681 tcaagaattt cacacatggc ttggagccgt tcgttcccga ttgttctata aaccttctcc
    49741 tcggcttttc gtaaaggcgc aatcattctg tgggcgtata cctgtccgct ttcagtcaag
    49801 acgatccgct tctcacgttt atcgccctcg ctggcctcca acagtaaata gcccttcttt
    49861 tgaagtgcgc tcacgaccgt atgaaccgtc tgtttttgca taccgaaatt ctctgcgatc
    49921 tgcttttgcg tcagttctcc catggattcc agcgcataca gcaccatcat ttccgggtat
    49981 ccgatgccaa gtactgaagc tgcttttgta tatagcgcag tgcttttcgc ccacgcaacg
    50041 ttaaaatgat tgttttccat aagtcctcct cttacaaata atatttacaa atactattat
    50101 agtatattgt aaggactatt gtcaagggcg tatggagcaa aaaattctta tttgtcataa
    50161 tcattctacc ataccgttat gaataaatca tctcttgcaa aataatttct tctgcccggt
    50221 tgtgaatgtt attgcaacgc cgcacccatt ccatttgttg ggttcgtttc aattcctcgg
    50281 tcacgccctc ggcatctttc atctgctcca tgatggtgtc taaccgttcc tgtgcctgtt
    50341 cgttcaggtc tgcaaggtat gtccataact cccctgtcaa ggtcaaggtg ttcaatttgg
    50401 ctgggtggac ttctcttaaa tactcccggt gcatccgtcc gtactttccg atagggcgat
    50461 gttcctccgg cagcttcaaa tctgggatat agtaatctcc gacaaggata taatcaattc
    50521 cgttttccgt tattcttggt ttcaattcgc tcatgctcct tacctcctgt ggaagcaggc
    50581 tcgtctgata ctaactcaat cacatcggta atctcacaat tcagcgtttc gcagatacgg
    50641 gctaatgtgt ccatgctgat gtgctttccc tctttgctca tgttggcaat catattcgtt
    50701 gtcataccgg cggcaagcct taaatcttct tttctcatat cacgctctaa cagtgtatgc
    50761 cagagtggtt tatagctgat gtgcatattg ctttcctgcc tttctatcca taccaccggg
    50821 gcggctgccc cggcaggaac ttttctctta ttatagcacc aatcttgtga aatcacaatt
    50881 tattcttgta gcctgccgct gataccgtct ggattgtgct tttcctttct ttttgttccc
    50941 tttaattagc cataaactgc ttgatgccct gagatttcgc tcccggatta tcattaccat
    51001 atccttccat aaggttaata actccccatg ctccaagtcc agcacctact gccataacta
    51061 aaatctttaa tacatttact gcctgtgcga aaaattccat aatttattcc tcctcatttt
    51121 cttctttctt ctcaatcttg ttatatgact tcactacaaa gtttttgtaa gtctttccct
    51181 ctttttcacg cttcttaaag tagccgaata catgaatcaa atcgcctttt tcaaagtcct
    51241 ctgctttctc tgctttttct ccgtaggctg cacaattgat gtactccttg ccctttccat
    51301 atttttttac aagcgtaaag tttacaactt ctacttcttc accctctttt tcaaaacttg
    51361 agaaagtagg ttctgccact aagttggcgt tgatgttaat catttcttgt ttcatctttt
    51421 taaatttctc cttttcattt caataaaaaa aacgactgga gtttttcttt tccaatcgct
    51481 gatactctta ctatttagtt ttcgtttaag tgggatttct gatccttatc atcttgcctc
    51541 ctgattttga ataaaaaaac agcaaatctt tttaagactt actgcattct tgtaataacc
    51601 gtctctctat ttaattttgc ttttcctttt cgcttcatat agctttctat gtcaaacaaa
    51661 ttcttcttgt cataatcctc aagcagctta taattcttgt gctttgtaat atcgtattta
    51721 tctgaaagaa aaggtctgac acctctaagc tgaaatatac attttccacc gtccattaca
    51781 gtaatctcat cttgactcat cagttctttg ccacaatgtc aagtgatgaa ttaaaaaaag
    51841 ctatcaaaga aatccttctt cgatagcagc gtattcaaca tctattcaca tttcctgcct
    51901 tgcgttcttc gagctgatga aatataataa gaaatgttgt cggaggtgcg aatatggact
    51961 acatgacgct caaagaggca agcgaaaaat ggggcgtttc gtcccgacag ataaattatt
    52021 actgcaccga tggacgcatc cccggtgctg tcaaaatggc cggtgtctgg ctgatcccca
    52081 aggaggcaga gaagccaaag gacagacggt ataacgaaag caggtgatac agtgctgcat
    52141 atagcaattt gtgatgatga aaaagacttt gttcagtatt tgaccgattt actgaaccaa
    52201 tacagcaagg aaacaggacg ggacataaag attaccccgt actatgacgg tatggagctg
    52261 attgaaaaat acgatccaac catagacctg attttccttg atattcaaat gaaggtggtg
    52321 gacggacttc atgctgccga gcgtatccgg caaatggacg aaaccgtggg cattattttt
    52381 ctcactactc ttacacagta tgggcttgag ggatataaat accatgcgac gaactacatc
    52441 attaagccca tgaaatatgc ccggctcaaa tcagaaatgg acaaattctt ggagcgcagc
    52501 cagaaagaag ataccccctc tctggtgatt accaacgata ccggcaaata taaggtgccg
    52561 ctaaaatcaa ttcgatatgt tgaaacatat aaccgcaatc tgatgttcca taccgagcag
    52621 gaaaatatta tctgctataa gagcatgaaa gaagtggaac gggagctttg cgacaaagac
    52681 tttgtgcgct gccataccag ctacattgtc aatctgttct atgtgaaagg catcaagaag
    52741 ctggacattg aattgattac aggcgagatc attcccatca gccagccgaa acggaaagaa
    52801 tttatggaac ggctgacgga ctattggggg gatatgctgt aatgtggtta tatcaagtgc
    52861 tcgacataac agcaacgctg acagaatctt tgggactgta tttattcagt atttgttttt
    52921 gcaaagaacc acggtatcgt gcttctgtaa atagatggct tataacaggt ataagttttt
    52981 tgtgtgcgta tacattgaca tggttttctg aacttggcgc actcaaagcg ccttttcttc
    53041 ttacgattta tcttgtcctt ttgaaagttt gttatagaga ttctgtctat caatgtgctg
    53101 ttgctgaaga actgaattat attgcaactt gttctcgata ttcgcaaggt agcgcgggga
    53161 aatatataac tcgtcgctta cctttttgcg gctctcgccg tattcatttc tcgcggcttt
    53221 tatagctgcc ccgaaagcct taaagtcgta caatggtacg ggtctttttg ccattttcat
    53281 tcaccctgtt acattttaca gttcaccttt ctttttggat atgtccacac aattcatatc
    53341 attaggttaa atacttcctg ttgtgtattg acagtagact gattttctga taaaataaaa
    53401 tttatgtaaa aggaggcggc gtttatgttg catagcatgc gtattagata agcattgaaa
    53461 aaaaggattt tcccattttc aacatgggct tttttgtcat gcttattttg cggatgctat
    53521 acaaaaaact aacgacgtat agatatagta tagacatagt gcaagctatg ccttagtttt
    53581 gttgtactgc tctgtgcatt ttttgggtag ggaaaccacc ggctgtgccg gtggaggtac
    53641 cccgtaaaaa agctttagct tcaagcatcg agcgaagcga gctgctaaca gcaaattatc
    53701 agtgaagaaa gacttgcatt agaacagcgg ctgcccgttt acgggctgcg gggcaaatga
    53761 tgcgggtgaa ataaaattca gtgcgtcttg agacgcatgc cggtaatagg cccttatagg
    53821 gccaactcaa gccaccggct tagccggtgg ttatgacttg tgtaaaaagg acgagtgaaa
    53881 tataatgctt aaaaaatatt ggataaaatg tccgatttgt aacggaaaga cgagagttca
    53941 agtatttcat aatactgtat taaaagattt tcctcttttc tgccctaaat gcaaattgac
    54001 gcatatcatt gatgtagaaa aattagagat tgtaatcaaa aatacagaaa aacaaacttt
    54061 tattatttag aagaaaggat ataaaaatga aacgtttacc taaatatacg cctgcggaag
    54121 tacggaatga tccatacgga tttacttaca aagaaatgtc ggaagttatt ggcgagaatg
    54181 aagcaaaagc cttatatgaa gaattatata agcaattacc acgcaaaaaa aatctatcaa
    54241 tgttggtaaa aaatatttgc aaaagcagtg atactgaaaa gtatgtttac gaactgaaag
    54301 acaacaaata cattgaaacg gtttttatca agcggcgaga tggtggaact gtttgcgtga
    54361 gcacacaagt cggttgtcct gttggttgta ttttttgtga gtccgggcga aatggctttg
    54421 ttcgtaatct aacatcgtca gaaatcgtac aacagattat attgttgcgt cgaaaagtaa
    54481 accgtatcgt ttttatgggt atgggagagc ctttattcaa ttatgacaac ttgataaaag
    54541 caatccatat tctccgagat agatatgggc tcaactttcc aaccgacggc attaccatat
    54601 caacagttgg tccggtcgat caattaaaaa aattgcgcga ggaacatctt aaaattcagt
    54661 tgacaatatc tttacacgca gcaacacaat ctgcaagaaa tcgtattatt cctcacatgc
    54721 gcatatatgc tattgaagat gttgttaagc aagccttatc ctattctgaa aggcataatc
    54781 gcaaaattgt ctttgcgtat ttgcttttac cgggtataaa tgaccggccc tcagatgtaa
    54841 gacaacttgc aaaatggttt cggggcaaaa aagttatgat taacgtgtta caatacaacc
    54901 caacaagcaa ttcaagaatt aaagcaccac agaaacggga aatagttgca ttcaaacatc
    54961 aattagagca agcaggactt gaagttacta tgagagtttc tcatggcaga gagattaacg
    55021 cggcttgtgg acagttagct aacacatata ataaattcaa aaaaaaatga ttaaaagtgc
    55081 cagacgcata gacgcagagc cgataacgca ttaggtcaaa aaacctatgt gttatcggct
    55141 tttttattta atattgcgca aaagccgctg ttccctatta tagaatggat tgcgggtagt
    55201 gtattaaagt cgcccttttt taaggatacg gcggtatcgg ggaggtatcg ccgtgtccat
    55261 ttttatttac tgtaacccgc ctaatgcttt gcggtcaaaa aaagctatgc tccgcaagcg
    55321 ggatattccg gctatgaatg tgaactgtca atacatttag ctactgctta catttccttt
    55381 gcgcccgtcc gcgtcttgcg gacgggcgca ttttgctttt ttcaactttt ttctgaaaag
    55441 cgcactcaag agccatctcc cgaacgggta cggagcgaaa ggggcagaga ggacaagccc
    55501 ttaactcccg tcctctactc cacgcgggaa ggaggtgaac tctatggagc tatcttcttc
    55561 cgacaaggaa agaatacaac atcagtacga cgcattagca aagaaaactt tggtcggcga
    55621 agcgaaaagc caccgccgca ctcttgcgaa acgcgcagca cgcgaagtta ctttttcgga
    55681 tttgagcgaa agcgaactcg cgcagctttt cacaacggac gaatacgaaa gcgattattt
    55741 ccgttttcaa gtgtccggct ttgatgtact cgtcaaaaat gaactgcttg ccgaagccct
    55801 taacgctttg cccgaaagga aacgcgacat tatccttttg tcctacttct tggatatgag
    55861 cgacgcggaa attggcgaac tgctgaatgt tgtacgcacg acggttttcc ggcacaggaa
    55921 atccgcgctt gcgaaaatca aacagtattt ggagggaaaa gcagatgatg aataccgtta
    55981 ggaagtctga aaatctgttg ccgttccctg tcatttccgc agcggcaaac ggcgacacaa
    56041 ccgccatgtg cgcgatcttg aagcactacg agggttacat agcgaaactt tgtacccgca
    56101 cgctgaaaga cgacgcgggc aatacctatt cctatgtgga cgaggaaatg cgtaacaggc
    56161 tgcaagtgcg ccttattacc cgcacccttg cttttcatgt aggataatct tttagcccat
    56221 gcggggagcg tgtccccttt ccacgcttcc cgttatgggc tatttgtcgt tccgcaaaag
    56281 catatccgct gttgatgtgc ttttgcaggc cgacaaagcc tattgttctt tgacaaagaa
    56341 agcggccttt ggtgcgcagc ataacaggca aacgggtaca ttccgtctgt accgagccag
    56401 tcggcgggta cgccatgaca gcttttcccc ataggggaaa agccgagcga gaactaccgc
    56461 gccgtaaaac aggtttagca gcttgtgggc gacgacatac aaggcggcac aatgatactc
    56521 ccgcgttgaa caccctcaaa gtattgcgcg gcgcacccat aagcatgggc cggggtgaaa
    56581 ctcccgtgag gttgcagcta acaaccgccc gtttttgcct tttgacgaat atagtttatc
    56641 catacaggaa aaggaggttt ttctaatgga taaaaaacag acaattacaa ccgaacgcaa
    56701 aatagggaaa atcacctatc ttgttcaagc gttgccgagt gaaaaggcaa ccgatacaat
    56761 ccataaaaag attgagaaac tcattgtaaa ggatttgcag aaaaagcccg gaaatccggg
    56821 atttttagcg tccgagtagt gcattaggcg gcgggatatg gtataatgat agcaacacat
    56881 tatacctgtt tattcggctg tcggaaagga ggactaatgt tacagtcgaa taaaatcacc
    56941 gccctttact gccgtttaag tcaagaggat atgcaagccg gagaaagcgg aagcatacag
    57001 caccaaaaaa tgatacttca acgctatgcg gacgaacacc attttttgaa cacaaagttt
    57061 tttgtggacg acggattttc cggcgtgagt tttgagcgcg aggggctgca agcgatgttg
    57121 caggaagtgg aagccggacg agtggcgacg gtcattacca aagacctttc ccgtcttggc
    57181 agaaactatc tgaaaacggg cgaactcata gagattgtat ttcccgaaaa cggagtacgc
    57241 tatatcgcga tcaacgacgg agttgacaca gcgcgggagg ataacgagtt tacccccttg
    57301 cggaactggt ttaacgagtt ttacgcccgc gacacaagca agaaaatccg cgcagttaaa
    57361 caggcacagg cgcaaaaagg cgagcgcgtc aacggggaat atccatacgg ctatatccca
    57421 gacccgaaca accgccacca ccttataccc gacccggaaa ccgcgccgat tgtcaaacag
    57481 gttttcgcta tgtttgttag cggcgtgcgt atgtgcgaaa tccaaaaatg gcttgcggaa
    57541 aacaaagtct tgacgattgg agcgttgcgc tatcagcgta caggacaggc gcggtatcag
    57601 cgggcaatga tcgcccccta tacttggccg gacaaaacgc tctatgacat attagcaagg
    57661 caggaatatt tagggcatac cataaccgcg aaaactcaca aggtatccta caagtcgaaa
    57721 aagacccgga agaacgaaga agaacaacgc tatttcttcc caaacaccca tgagccgctt
    57781 gttgacgagg aaacctttga acttgcgcaa aagcggattg ctacccgcca ccgcccgaca
    57841 aaagcagcgg agattgatat tttttccggc ttgctgtttt gcgctggttg cagacataag
    57901 atgtattacc aacagggcgt aaatatcgag ccgcgcaagt tttcctattc ttgcggcgca
    57961 tggcgcaaca gggcaaggac aggcagcgag tgtacctctc attatatccg caaaaacgta
    58021 cttcttgatt tagtgctgga agatatgcgg cgggttttgc ggtatgttaa ggaacacgaa
    58081 caggacttta tctgtaaagc taccgagtac ggcgacatgg aagcgagaaa ggcattagcg
    58141 cagcagcaaa aggaactttt caaagcacag gcgcgtatga ccgaacttga cacgcttttc
    58201 cgcaagctgt atgaggacaa cgcattaggc agactgacag atgaacggtt tgtgtttcta
    58261 acttccggct atgtggacga aaagaaatcc cttgccgcaa ggatagacga gttacaacag
    58321 cagatcgcaa ccgttaccga gcgaaaaagg gatatatcaa ggtttattca gattgtcggg
    58381 aaatacagcg acatacagga attgacctat gaaaacgtcc atgagtttat cgaccgtatt
    58441 ttgatacatg aattagaccg ggaaaccaac acccggaaaa tcgaaatcca ttatagcttt
    58501 gtcggacagg ttgataccga gcaggagccg acgcaagttg tcaaccatga ccgccgcaac
    58561 atggtagatg taaaaagtat cgctatctaa ccccagcaaa aaaggggcct gaaatgaaag
    58621 agtacacgct aattatcaag ggagaaatgg attttatcat cttatctccg caggtgcttt
    58681 cttccctgat tactcaaatc cataacagcc cggagcgaaa agttgtggta agtattgaga
    58741 gcatcatgcc accaaagttt accgactatc tgcttcgggt aatcaatagc aaccgcttta
    58801 gcaatgaacg gttccgctat cgctacattt tagaaaatcc tgttacaaag aaagggatgt
    58861 atgagatttt acggcaacag ctttcccgca ccaatacgga gcgatttcct tgttttcaga
    58921 ccatacaatt gaccgacact ttccagggta atgtggagct ggacatggag tgcaacgatc
    58981 tgttcttttg ggcttgcaaa gatacagcag caaagtttgt ttacacgttc ccggatggac
    59041 gggaggaaac actggtgatt gaatactgaa tgagaaaagc cccatccctc aatggttgag
    59101 agatggggca aactatttac gctgcaatct ccgggatttc cccgacaaag ttataaacaa
    59161 ttctgacttc ctgcaccttc tgaccgtcca ccttcttaac ctcgccgatc aggattttgc
    59221 tgataagccg gttcagtacg gactcgtcca gttccgcaat ggcggcatag cgccggattt
    59281 ccttgataaa ggttcggact tcgctttcct gtgcgtccgc ccggctctgc atcaccgcca
    59341 gatcgtgcag gcgtttctga ttggcttcct gctcctgttc cagcgccgcc gtcagcttca
    59401 taaaccgctg ctcggtgagg acgcctttgg ccttatcggt gtacaggctc aaaaacatcc
    59461 cgtcaatttc ctgattccgg tcttccagcc gtttccgttc cttctctgtc tgggaagcgt
    59521 ccaccagata ccggcgctcc atccggctgc tgagccgctg gtagaacgca tcggcgtcct
    59581 tcatggcctg cgccgccaat tcctgtatat ccttcagcac cagattgtac aaatcccttg
    59641 cctcaatctt gtggctggta caggcgttct tgcccagccg gttgtaagtc tggcagatat
    59701 agtatgccct gtcaatcggc tcccgcattt cgccggtgaa gcggttcttc ccggttctgc
    59761 cgaccttttc ataccgcacc tgcatggact tcccgcaggt ggcgcagtag acaagcccgt
    59821 ggaacaggtt atagaagggg caggcgttgc ctttcataat ggttggcctg cggtcaatga
    59881 tgtcctgtac ctgttcccat tcctccggcg tcacaatcgc ttcgtggcag ccctcgatga
    59941 cctcccaatc ctcacggggg ataatgtcat aagtgttgga gcggatgcct ttctggtgtg
    60001 tccggcagac aagatgtgcg cctttataaa agggatttct caggatatgg ctgatccttg
    60061 cgctccccca tgaatagtag ttcacgtcac attctgtatt gctttttact ctggtgatgg
    60121 ggattttatc atccatgagc tgctttgcga tccgcataca gccccagccg tccagtgcca
    60181 tatcatagat ttttcggatc accggcgcag tctccgggtc aaggatcaga tgccctttgt
    60241 cctccgggtc acgcatcagg ccaagaggcg gctgcccgcc gcagaacttt ccctgccggg
    60301 aacgggtcat gcgtcccgcc agcacctttt tggaaatatc ccggctgtac atatcgttca
    60361 ggatattctt aaagggcgtg atgtccattt cctgacgggt caggctgtcc acaccgtccg
    60421 tgacggcgat atagcgtaca ttgtgtttgg ggaaaaagat ttcgatatag ctgccagctt
    60481 cgatataatt cctaccgagc ctcgataggt ctttcgtgat gacgcagccg attttccccg
    60541 cctcaatgtc agcgatcatg cgctggaacg aggggcggtt gaaattgcga cccgtatagc
    60601 cgtcatccac ataatactca tactggaaca tcccatgctt ttctgcgaag tcccggagca
    60661 tgagtttctg gttgctgatg ctcatgctct cattgtcgcc gccgtcatcc agagaaatac
    60721 ggcagtagag agcggtgatt ttttcataga cttgtttttt cctgctcata gcgttctcct
    60781 tctatgaaca gggacacgat accattatag taccatgtcc ccgtccctga atcaaccgtt
    60841 tttacgcagc tttttctgcc atttcccgct gatgacgcca ttcctcgaag tgttcgcagg
    60901 tctggcgctc aatgagctgc tcaaaggctt cccgcatgga cttctccccg gagaactccc
    60961 gcaccaccac aaaacggact ttattcttct gatttttgct tttttccata ggctacctcc
    61021 atagagagac aggccgaacg gcagcaccgg caacgaagtc cggcaacgaa cctctaaaaa
    61081 cctgtaaact accgtctggc ctgcaaatct tactttgtga attttcttga aaaatctcgt
    61141 tgctttcgtt gccggagata atgataaata ttaaaatatc ccttatttac tggctttttc
    61201 cgtatccaga cagggaaatc cccggcaacg aacccggcaa ccaagtggca accatcccgg
    61261 caacagaccg ccattttcag gcgatccact ccttcggaag ctccaactgg cggcattctt
    61321 cctcgctcag ttccacaaat ccatcttcgt tgccgggcag ttcgttgccg gaaacgtccc
    61381 gttcccagcc cttctgcctg ccgtatccgg cgaacatccg gggattggag aatggcttcc
    61441 agcccgtcac cactgtattc atgatctcgt tgatattgtg aagctgccac cgcttcggct
    61501 cgtcataggt gtggcccaat gcctccttaa aaagctgttt ggaacagacc atgctgccgg
    61561 tataatgttc cagaaagccc tgtatttgac cggcctccgt gtcctccggc atgaaatcct
    61621 tctgcacctc cacaagctgc cgctggatgg acttgctgaa tttcatggaa tacttcccgc
    61681 tgcggtagat ggtcatggcc tccgcccaga cctgcaacag gtaggctctg gaagcgtcct
    61741 cgtcctccaa aatgtgaacc tccgctttct ccgggtaaat catgatggga aggaaacgcc
    61801 ggttcccggc ccggtcaagg ggcaggaagt ccagcgtgtt ggatgaaccg ccgaacacgc
    61861 actgccgcag ccggtctttg ggctgggcct catagggtgt gcggtaggtt tccttctggc
    61921 gactgatgaa cgagcggatt tcctctatgc ttttggcgct gctggtggcc agcatctctg
    61981 acatctcaat gatccagtgg ccttgcagct tcaaaaatac ccggtcatcg tccagctttt
    62041 tcaggtcatc ggagaaccac tcgtcccgga tcgccagcag gcggaagaag ctggacttgc
    62101 cagccccctg tccgcccacc agacagagca tttcctcgta tttggagccg ggagaaaaca
    62161 cccgccggat ggctcccagc aggaagtgtt ttaacatttc ctctacataa tcgctgactt
    62221 ctgcacctaa gaagtgatgg agacaggagc ggatgcgggg cgtcccgtcc cacacaaggc
    62281 cgttcagcac gtcctgtatg ggatggtagc agttctcatt cgccacgatg gagagcgccg
    62341 ccgtcatttt cttctcgctg gtcaggccgt agttctgctc aaaatagaga agcagatact
    62401 tcacatccgt atccgtcagg gcgctggtgt tcctgcgcca gcccaaatcc cgcacgatgt
    62461 ccacccggtc agtcaggagg ttcagccgga tggcgtcccg caggagaggg tcatgggaga
    62521 acaccgtccg gcagttgccg atggtgttgg cgggctggcc cttctccgtg acagaaaggc
    62581 cttcccgcac ctcgtcaacg ctctgctccg gcgctaaagc ttcggctgcg ctcatgacgg
    62641 cctgccgggt ggctggcggt aaactctgat attcgctgct caatcttcct cacctctttt
    62701 ccatactcag cgaccacgca ggcccgttcc tccatactgc cggacagcag aatatccagc
    62761 agatactccg tgtacggctt tttttgcagg gcctccacaa acagcgggtt ccatgcttcc
    62821 tccggcgtct gcggggcata ttccttctcc cagcgttcca gcagatgcag ataatcgcac
    62881 aacacccgga aacatttctg ttccgcctgc cggtagcgca gttcctcgct gatttttcgc
    62941 ttgcccggct tcctgcgggg cgggtcatgg cctttagcgt caaagccgac cgagaaatcc
    63001 tccgccagct tcaaggccgc atctttcttg ttcagcccga acagacgggc ggtaaaatca
    63061 atcacatccc cgtccgcctg acagccgaag cagtggaacc ggcggtcaac cttcatgctg
    63121 ggatgtttgt catcatggaa gggacagcag gtcatcccgt tcctgccgag ctgtatccca
    63181 taagattccg cagcctgcct tgtggggaca gcctgcttca ccgcttcaaa cacattcgat
    63241 tttctcacct ccagacagag aaaaaggcat ccggttttca cagaaaatca gatgccttac
    63301 aactctatat cgttcttttt ggtcggggcg attcgcccct cacgttccca acgctcccgg
    63361 ttatcccggt cagcattaat ttttgccttt gccagaatat ccataatgga ttctttggct
    63421 ttcttcttga cctgctcctt cccggcttgc ttgacttccg gctgcatcag cgtccgctgg
    63481 attttcgcca gagcgtgctg catggcgttt ttgattttgg taatgacccc atccagacgc
    63541 tcagcggcat actcacgttc cttctttgga gctttgcgct ccggcgaaag cacccatttt
    63601 ttcgattcct ccaccagacg aatatcttcc ttgtgcgtct cctgccggac ggtatcggtc
    63661 accacctcca ccgccttgtc ataggccgca tcggaaacat catctaacag tgtctccacg
    63721 tcctcaattt tgagcgtcag ttcttccagc ttctgctcct gcgccgccag ttgctccttc
    63781 tgtttcatca ggatataatc ctgtttttcc agatagtccc gcccgccgta ggacggctcc
    63841 tgatccagat gtagcccatg ccgtctggcg atgtcaaaca gaatcgtccg gcaaaccgca
    63901 tcaaaggtct gcttgcggtt gttgttccgg cctttgggct tctcagggtt tgggagaggg
    63961 atgcccagtt cttccagcgc cttttcctgc tggggacaca gttccccgta gcggttctca
    64021 cagtcaaaga cgtgccgctc atggatgtgg ggcgtcccct cgtccagatg gagcgcccag
    64081 tccaggatgt ggatatggga accgaagcgg cgctcaaatt cctcataaaa ctcattgacg
    64141 atggaaaaaa gcgtgtccgg cgggacggat tctcccatcg tgccgatctg gtagatgctt
    64201 tcctccgggc aggtcttgtt gtttttcagc aagtcctcca cggtgcggtt gcgctccgtg
    64261 tgccgggttt tctcattccg ggcgttctgg gcctccacat ggccgccgta atgctcgttg
    64321 tagtacatcc gctcgatttc ctcaaagctg aaatccggct gctccgggtt ctcccggaac
    64381 tcgtgtgtcg taaagccccg gtagcagtcc cagtagacat tttgccttgc ccgttctgcg
    64441 tcaatgtgtt cgctgttctc cacatcgaac cggcggtcat tgtggcgggg attataggtg
    64501 ccatgcttgc cggagcgccc attgtgtcgt gtcagtttca aacagatttc ctccttcctg
    64561 cgaagatgtt ctggggccgg ggaaggggcg gcgaagccgc aaatcctgcg aattttgcgt
    64621 caggtaatac ccagtacgag ttgacgcagg catcaactct ccctgggcaa ggcgtttcac
    64681 ccttgacccg ataatggctg ccgcccttaa cctgccaatg ggcgttgccc cttgacccca
    64741 gcagtgcgct gccgcccctg caccccggca caaagggctg gctgccctct gtactcccgc
    64801 accggcgaag ctggattcca ccgcagaagc ggtgtttgcc agtttcaccg gctccgtatc
    64861 cgcacatttg cgcccataag cggggaatgg atacggaata cgcctgcggg gattgccggt
    64921 caaaacagcg ggtgcagacc cggcattttt tccgtaaacg ccccggtttc aggcgatttt
    64981 ttcttccgcc cctaccacct gaaagccatg ctcttttgcg taggcgctgg cggcggcttt
    65041 ccgttcctcg ctgtacggcg gcaccagccg gatcgacagc cgggacttat ccagcacata
    65101 ggtcacgctg ccctccggcg tgctgcgctc caaccggcac agcagcgggt acttccggct
    65161 gaaatcagcc agcctgcgct tcaagctggc gttgaaggtg tagacgctgg caaggttttc
    65221 cgcctcgttc cagttgataa tggtttcttt ctcatactta gacagcttcc tcatacagat
    65281 cctcctcata atcagtgtaa gatttcagca cacgcaggct gcgcttgagg cggcggtact
    65341 cgtccatctc catccgcaga tggtggtaaa aatcctcgta ccagttttcg cccacctccg
    65401 tctccacctt ccgggccagc cccagcatcc ggcgtttggc ctccgggtca accgtcagtg
    65461 ccgtcagcca tttcagccgt gtcaccgtat tgtggtggct gggacagccg taagcgtaga
    65521 gaatcttctt ttctttcata ctcagtgtca taatgatttc ctccgtttct ttgctgcgga
    65581 gccatgcgcc ccgcatgatt gataaacttg tttctgtctg ccggtctgcc tgcaagccgc
    65641 tcctgcccgg aatttctccc ggcgtatcgg cctctttggt gcgctcgatt tctgtcctgg
    65701 cgtcacttcc ccggaggcca taccccttgc agccggtcat tcgattttca aggttctgtg
    65761 cctgtctgca agaaccagtt taccgaaaaa agaggccctt tcccgtatat ccaaaacgtc
    65821 ggaaaaacgc ttgaaatccg catatttcca cgcttatgga atcgtgctat aatgggtgta
    65881 atcactgaaa aacgataacg agagaggggg ctttggatgt acgcaaagct gacaatcccg
    65941 gagcggctca aagacctgcg ggtggtagat aagcacctga cgctggaaca actggcggag
    66001 cagaccggcc tgtctaaatc cgcgctggga aaatacgaaa ccgatgacta caaggacatc
    66061 agcccgtttg cgattgcaac gctggcggac ttttacggcg tgtccaccga ctatctgatg
    66121 gggctgacgg aaaataaaaa tcacccaaac atagaacttc aatctctgca tctgagtgat
    66181 gatatggtgg aacttttgag cagcggcaaa atcaacaacc ggcttctctg cgaactggct
    66241 acccacccga atttccggcg gctgatgata gatatggaaa tctgcatcga ccagatcgcc
    66301 aatatgcggg tggagcagat gaatctggtg ttggaggcca cccggcagac cgtcatgaac
    66361 aagtatgcac ccggagaaga tgacctctat atgcggacgc tggaactggg gcaggtgcag
    66421 gaaagcgatt tttacagcca cgtcatgcac gatgatctgg acagcatcgt ccgggacatc
    66481 cgggaagcac accgcaaaga caagaccacc gccgacccgc agcccacgct ggatgatgtg
    66541 aaggaaaaat ttgagcaggc catagggcag ggcagcgata cagaaatgct gatccacgag
    66601 ttctgcgata agttgcagat accctttgag aagatttcct cggaggactt ctcggcgttc
    66661 ctgcggatac tgagcctgtc caagcagctc aaaagctcca acaatatgag gggaaaggcc
    66721 agccccattc ctcccaaccg caaggccaga cgtaagcgga agtaaaattt ccatatccgg
    66781 aagcggcaaa aaagccatcc gccgattgat tggcaaatgg ctttcgtgaa gctgtattct
    66841 gttgtagtgg ttgtgcccag tttgggaaca gtcactattg aagatgctat tctttgtctt
    66901 tctgcgatac ctgtgcatgg gcttcctgct gaacaagcag ccccgcagaa aagccatatt
    66961 tgaagtggct ttcgttttcc tcacactggg cgattgccac ctgctcccgc agttcttcaa
    67021 ccagtgcata gtcctctttg ctcagacgct ccgataaagt gtccatcagg gcggcgctgg
    67081 ctttgactgc ctgcttgaac ctcggtgaat cagcgaccac cgtttcacag ggataaaatc
    67141 tgccgttata catttcttcc agaatcatgc acccacctcc ctcagacaaa aatcatctca
    67201 gacaggatga tttcctctac ccggctgcgg atgctgttca tgcccccgac ccatgcaagc
    67261 tggtcacggg ctttcagttc ctcggtgacg ccctccgcag cctgcatctg cgagatgata
    67321 cacgccagtc ggtcatcggc ctgctcgttc agatcggcaa gatacgtcca gagttttccc
    67381 gacagaagca gttcattgta ctggccggga cggtgttctt gcagaaacgc cttgtgtatc
    67441 cgaccccacc gcccgatggg gcggatttcc tccgacaact ttagatcggg gatatagtag
    67501 tctcccacca gcgtatagct gatgccgttg tgatggattt tctttggtaa atgctccatg
    67561 ttcgacctcc tgtattcagt tttttcagaa tccagttgat cgtgtccctg ttcatgtgaa
    67621 attcaaggca actgaactct tcacgaacaa gtatggcata tccttaccag tcttttgata
    67681 gtttaaacca aagctctttt gatttgacct tgtttccgac gtgttataca ggtcgatagt
    67741 ttcttttccc agtgtttcag acaattcttt tagcgtagtt ttctccttgc caccaagaaa
    67801 caaggtacta tcacagttac ctacgattgt atcagcgtta tccttgtaga ttgcctttag
    67861 ctgagattgt gcttgaagta tgatacttgc tgaaatctct cttgaacgga ttgttgcaat
    67921 taacttctca aacttaggaa ttaagccgat attagcgaac tcatcaagta gacacctcac
    67981 atggacaggt aatcgtccgc catatacatc atcggcttta tcacataaaa gattaaataa
    68041 ctgtgagtac ataatggata ctacaaagtt aaatgtatca tcggtatcgg agataataac
    68101 aaatagtgct gtttttctat ctcccagtgt atcaagctca agttcatcgt cactcatcaa
    68161 gtccctaagt tcctgaatat caaagggagc aagtcttgca ccacaagaaa taagaatcga
    68221 tttggcagtt tttccagaga caaattgtca aggacttttt catcaaattc acaaaaatct
    68281 acaaaaaagg tgccagaagc actgtatggc tcctgacacc tcgtttgata gattacattt
    68341 ttccgttcag caggtctttg cagagatacg catagtctgg cagctggttg atatatggct
    68401 cccagcgccg cttgatttcg gccaattcca gcggatcggc tgcttccagc gcgtgatcgt
    68461 tgcccgtcat atataaaaca tccgtagcta catcgtccaa acacctgtaa cagagatcgg
    68521 cggcagattc gattctggta ccggtatcca catagactgg atttacgcca atcgccagcc
    68581 agacatagcc taccttgtcc gaccagagca gttcaaaatc agggctttgc cgcagatgtt
    68641 ccgcaaagac ctcctttact cgttcaattt catgcttctc tttttctgtg taaagcattt
    68701 tcgtgtcctc cttgacaaaa attttggtgc gtaccattat cagtttagca caaggcggct
    68761 tcgtttatca gtctgtcaca tctgctgaat ttcatttttg agcatacgct tgattttatc
    68821 gctcatggtt tctgtgctgg tattgctgaa atggacatga accttgtagg ttgtcttacc
    68881 gattttcttt accatcgctg gcgtgttttc cggcgctctg gacgcagtag cggcgtctga
    68941 cacctgcata gtacggggtt ctttgttcat ggcgctcctt tctccgaacg gttctgtgcc
    69001 gcccggtaaa aaatcaatcg tgcttactgt ttacaatgtc ttttgctgtc tgtcgggtag
    69061 caccggcatt ttcttcccgg aaattcttcc cgtcaaaaag aatcggcgca caccgttcca
    69121 aaatacggtc atagatacga gcgtgagcca gatcaggcgg gtttttcagc tcggacagtt
    69181 tcaagtttgt tgtgataatc atgggtctgc ggctgcgata gcggctgtca atgacgaaaa
    69241 acatctgctc catagcatat tcggtactgc gctctacacc caaatcgtca atgataagca
    69301 ggtcatactc gtcaaagctg gcaataaact ccgacctgtc ctcagagaac atcctggtca
    69361 agcggttcag aatggtggga aagttcgtca tcagcaccgg cacatcccgg tcaagcaaag
    69421 cgttggcaat acatccggcg aagaaagact tgccggttcc cacatctcca aacagcaaaa
    69481 gcccgatatt gctcttatat gcctctttcc agttctccac atatgcgcgg gccttgtcca
    69541 tcaggggatt ttggccgttg tcgttggcaa aggtgtagtc atagagatag cggtcttgca
    69601 aaccctgtgc ctttcggcgt ttgatacgct ccatgcggcg ctgccgttct tcagcagcct
    69661 tgcgctgctc ctcagcttcc cgctggcact ggcagatgca gcgcggcata aagtagccgg
    69721 atttcccaaa gcatggcaca acggtctgcc tttggccgcc gcatttctta cagtgaatga
    69781 gcccgtctga cgggtctata tactcgtcct cagccaattc cacaccggca gctgccttgt
    69841 cgatgaatgc ccggatttct gcggtaatct caatcataca gtttcatcct cctttacgct
    69901 gtaatcccgg ttgcgtgagg gtgtgacagt ttttttagcg tcctcaccgg cccagcgccg
    69961 gatggtggcg gcatggctct gataccgctt gccggtagaa gccatgtact cggatagctt
    70021 ttcgatgtac tggctccata cagtgggaaa gctggcctgt aagtctgcca gttccccgtc
    70081 cgtcaggaaa acattctggt aacggccata ggcgcgggcg gagcgtccct tctctatctc
    70141 tctctttatc tctatctctt tctctaactc tatctctatc tctggtggac gaatgtcgga
    70201 caaatgtccg ccgtttgtcc ggggcgcaga aagagcctta ttttgaagcc ttgcagcccg
    70261 ctttcgctcg gcctcggtag aggactggcc gattaaaagt tcgatgttgc tcatgtagaa
    70321 tgtgccactg tccagcactt ccacaagacc cagcttcaaa aagatctgca aggctctctc
    70381 cacagtgccg atctgctggc gggtaatggt ggcgatcatc tgcgccgtgt aaggaatgtc
    70441 ctcgtcaagt tgaagccgtc caccatgttt cagcgatttc agatacagct tgagcagaat
    70501 gttggaatac agcacaccat cctgcatact ttccagcagc acgatggaat catcgtcaaa
    70561 atagttttct ttgagtttca ggtaataata ttttcggttg tctgacatag ggttcctcct
    70621 tggggtttct cttgggattc tgtacgcatt ttaaggccgt tttaggggcc ggaggataaa
    70681 tctatcagcc tgcctttgac accctcgaaa aaatccttga tttacaaggg tttttcagcc
    70741 cctaaagcgt gacatttctc ccgttgtttt cgcttacgct ttgcggcgtt gatccgcttc
    70801 atgcgtgtgg cacattccgg gcagtatttg gccctgttag aaccgggggt aaacagcgcc
    70861 ccacatacgg cgcatttctt agcattcagc cggtggaaca gcgccgtttc cagttcctta
    70921 tcctgcggca ataccgccgt ccgaaaccac cggcataaca gggagtagga aatggactgg
    70981 acacagacac atttctcccc atcatccagc gcgatacagt tgccgccgat gtagttgcag
    71041 cactcatgta ccagccgccg cgctctgcgg tactggcggt aatccatgac ggggataggt
    71101 tcagacttat tattcttcat aaatgatttc tttcataaag ccggtaacct ccttgaatga
    71161 atttattgtt aaatattcgt gcaaagtatt gttttcttcg tgcaaatggc atatactata
    71221 attgccagca gaaaggggtt gatcgtatgg ctggaaatac cacaaacatc agtatccgca
    71281 tggacgcaga tttgaaagcg caggcggacg cactgtttac tgaacttggc atgaacctga
    71341 ctacggcgtt taacatcttt gtgcgccagt cgcttcgtga aggcggcatt ccctttgaag
    71401 taaggctgga acagccgaac aaagaaacgg ttgctgccat gctggaagcg gaaaggattg
    71461 caaaagaccc gtctgtaaag ggctacaatg accttgacga gttatttgct gacctgaaaa
    71521 gatgaaagaa accaaatata ccgtcaagta cacgaccagt ttcaaaaaag actacaaacg
    71581 agccatcaag cgtggcttga agatcgaact gctggagcag gtcgtagcgt tgctggcgat
    71641 gggcgaaccg ctgccggata agaaccgtga ccatgacctg tccggcgatt gggcaggcca
    71701 tcgggaatgt cacattctcc cggactggct gcttgtctac cgcatagaag atgatgttct
    71761 ggtgctgacg ctggcccgca ccggcacaca cagcgacttg ttcggcaaat aaacagtctg
    71821 ccgccgtatg gggaaacctg tacggcggtt tttctgtgtg caaaagtatg tcgtgaaatg
    71881 cgatgcactt gatatgggta cgccaaaatg cagtatcctt taccgatccg gctcccggtc
    71941 gtgaggctta tcccgttcct gtcgggacag ctgctcggcg gttttgcgga gccgttccac
    72001 tgatttcaaa tcctcccgca tggatttcat ggcaagcgtg tccgtctgct ttccagcggc
    72061 cagctggtca atttccagct gccatgcctt cggggttatc ccctcgccgc tgtctttcag
    72121 ttctttcaga taccgggctg ctgcatcata caggatcagt tcccggctgt ggcgctgctc
    72181 aaactgttcc cgcttttccg gctttacttt ggcaagctgc ttgtggatgg acttgtactg
    72241 gttgtactgt tcccacatct ccccgcgttc ggtaagaatg gcgatccgac gctcagcttt
    72301 gacgattttt ccccgcaggt catagtaacg gctgttcata tcagcgattt tttcatgaag
    72361 ctgctgcata gactggatgc cgtttgcctg caaaaagctg aatagtgcag cgctttcctg
    72421 caaagcccgg attttgccgg tgcgggtgtc aggccgcttg agctgctgct gggcctccca
    72481 caagtcaatc atgctgggct gctgaccctc cggcttttcg gcttcggcct tagaccagtt
    72541 gtaaagacgg gtaatgcggg ctttgatttc tttcagcagc ttgttgtcgg cagcgatctg
    72601 ccggtttact tcgcccttgt cggtgcggat gccgcgcttt tccatttggc tggcggctgg
    72661 ccccagatgg acagagggaa tcttatcaat gccctgccgc ttgtagctgc gatggtcaat
    72721 gcgctccggt ctaccggcag attccaacgc ccgattggtg taggccgccc acgctgcccg
    72781 ccaaatctcc acatttcctt tatcgttcca gtcggtcgta tcctctctgt gatttttcca
    72841 accgcctttc ccatccggga tacgctggcc gttttcgtcc aggtcgtatg ccttgcggca
    72901 ctttgcgccc catgcgccat tttctttcag gggccggacg gtcatcatga tatgaacatg
    72961 ggggttgccg gttcccttgt catggatagc aaagtcggcg cacattcctt tgtctacaaa
    73021 gttgtccttc acataggcac gcacaagggc aagctgctgt tcgccggaca gttcacgggg
    73081 cagggctgct tcgatctcgc gggcaagctg gctgtccctt gctttctcga tttgctccac
    73141 gctgttccag aggatagatc ggtctgcaaa ttccggcggc gcatgggcag gcagcatgat
    73201 ctccgcatgg acaatgccgc ctttccgggt gtagtcgtgg gtcatgccgt cccattcatt
    73261 tgtcagcttg gttccgctgc ggtaagcagc tgcggcaaca gcagaacggc ctgcgctgcg
    73321 cttgatgata ctgacgggga tatgacagaa atctatgggg aacacctcct ttcagtgagg
    73381 ggataacagg ctctgtggag ccggacaaac gcaaagcggg tgtttggctg tgcagagcgc
    73441 acaaggggtt tggggagcgt agcttcccat cgcggacgaa gtacgcaatg cccccggcag
    73501 ggcgcacagc accggcaacg gtgtataagt gcgcccttgt aaacaaggga cttatggcgt
    73561 gtccccggat tttggcaggt ttgcagtcaa ttccgcagcc cccggaagat gagacagggc
    73621 aatcaaaaat gctttaacct ctgcgccgga aaggtcggga gccaacggga aaatcccctc
    73681 caaaacggct ccacgctcaa tcaggcggcg ggtgcgaacc ctgcgttctt cgttccgctg
    73741 cttgttctcc aaaatcttct ttcggttttc aagctgccga atctccttca ggactttctc
    73801 ccgttcttct ttttgggggt gggctgtaat tttttcgttc atgtcaggca cctcttttct
    73861 ttggaaatac tcatagattg accgtccatt tctgtcgagc aaagtaccgg cgcagcctcc
    73921 gcagtgcggc atggatggat tttcccgcct gtgatggcgt gataccctcc attgcggcaa
    73981 tatctttcac tttcataccc agcatatagc gggcgtgaac acggcgagcc tgcataggcg
    74041 gcagggagga aatggcttcg tacaatcgcc gtatcaattc ttcgtattcg gctaattctt
    74101 ctttttctat caggtagtcc tccggcgatg gctgcgccca gccgatggcg gcattttcga
    74161 ttccatcgtt acaatcgagg gaataaaacg ccttataccg gaacatcttg cgatctctgg
    74221 cggcctcggc tctcttgtcc agaagaaacg cttcgacgat ctcatcggac acctccacaa
    74281 aaatgtcctc tttgcaaaat ggataatatt gtttgaggtt gatggtctgc ataggcacgc
    74341 cctcactctg tttggaaaag accatcatag caacggcgca tattccgcag cccccgacgg
    74401 attgaaacgc tgaccttgct gctgtggacg ccctctctcc gggagatttc cggctgcttg
    74461 ataccggcaa tgtagtaggc gtgaacacgg cgggcctgtg tcggagtggc atgagccaga
    74521 gccaccggca gagctgctat cagatgcagg cgggtggtca tttcttctcg ttccagcaaa
    74581 atatcttccg gcgatctgct gtgttccagc gcgtaatttt ccagccagct gtatgcgtcc
    74641 agagagtagt aggcgcggtg gtagactttc cgacgctcat agttctccat ctcccgcttg
    74701 gcctgataca tcgctgccca tacctcgtcc gtaacatcta caaactcgtc atgccggtag
    74761 tggggataca tccaccgcag attgattgtt ttcataggct tacctcctga aaatcggaga
    74821 ggcggacagc ttgtccgctg tccgcccctc gctgggataa gggaaaatcc ctttcacttg
    74881 gtagcccgaa aacaggtcat tcgttaagcc tgttctcaaa gaaatttata aatttttttc
    74941 tgaccgcctc cacactttga tacacagcca ctttggagca gccgcacagc acaccgatct
    75001 ctgcaaggct cagcccgtca agcgcataga acaggaaccg gcggcgctgg gcctcggtac
    75061 aagtgtccag aacagccatc agctcatgca gcgtttccat gcggcaaagg tattcctccg
    75121 gcgtttcgct gtaaacgccc acgccctcgg taaaagctat gtactcgtca aactcccggc
    75181 catcccaatg ccgccgctgt tcatggaaca ggttctccgt tttgtgatcg gcccggtcaa
    75241 gaaattcata gacttccagc gtaacctcca cggccacagc ttgtccgtta taattgatgg
    75301 taacttccat ctgcctttcc tccattcaga ttttttcggg aaaatctgaa tggggtggcg
    75361 gagagcggca ccggggataa agttcgggcc atgctgaccc gatgttctgg ctccataggg
    75421 acaaaaaaac gcccggacgg cataaagcca tacgagcgta atagagtata ttttgctgtt
    75481 tagttacatg gtatagtgca tacttctgac cgcattgctc cgctgctggg aacaggcttt
    75541 ttttaactgg tgcagatcat ggatactgcg aaataaaaag aaggacacgg taaatcaacc
    75601 tccaatcggc taccgtgtcc ctgcaagtcg tcattggttt gtgcaaacgc aaagaaacgg
    75661 cggctctgaa aatcaaagcc gccgtttcaa atgggcgtgt caaattgtct gctctacgac
    75721 ggcttttttt cttttgccgt cgtccggcag agtattattc aatatttaat tcaatgtttc
    75781 cagtgaaatt ctcacattca atgccaatat aatttccacc atcaggaagt gtaattgtgt
    75841 cactataagt tccggttgcc tcaatcaacg tgactgcttc atcagatcca gaaatccaaa
    75901 atacttttgc agtaccttcc gtaatctcca aggtgcaatc aatagacagc tccttaccgg
    75961 cttctctctt tatggaagtt cctccgaaca aatactctgt acctgaaaag ttcgcataat
    76021 cagccgtata agtccctgta taatcatcaa ttcctttttc tttttcccct tgcagtgacg
    76081 atttccctgt cagttctatg gagcccgcag actgaacaat gttattgtaa tgattgagaa
    76141 tttcatcttt tgaacagcca gaaatcataa aacttcccaa aaggacaaat gctaatgcta
    76201 aaactatttt cttcataaaa tcatcaccag cctttctttg gagctacctt tttggccttt
    76261 ttctttgttt gggttgcttc tcgttctttc atgcacaaaa tcaagatggc agaaataacg
    76321 acagcaagcg caagactgca agaacaggtt ccaatattcc agttgactgc ggtatcatag
    76381 ctacggtagc ctaccattcc aagacttgcg gtaatcggat aaaggtttgc taatgtcata
    76441 tttcctgcgg caaacatccc tccatatcca tagacaaaag caatgattac accgactaaa
    76501 aagctgcctg ccctccgaca agtaagagcg ataatcggca gaaccgcaag atataaaaag
    76561 aaattaaccg cagtaatctg caaggctgct tttagagcta aggaaatctc aaagccggga
    76621 aatcccacaa tcatttctgc tatgattgta aacagactgc atatcagccc gaaaataata
    76681 gacaatacgc cgcacacaat caattttccg gtcaacagtt tcttaaaaga gatcggcaca
    76741 gtcagaatat ttttcaatgt gtcatccgtc tgctcacgag aaatcatata tccagcaatt
    76801 aggctgatac acatcggaaa aatcatggac atattgtttt tgatgacctg ttctgtaaga
    76861 taggcaaaat cccaaacgga accatcattc gccatagagg taaacaaggt cagcaggacg
    76921 gataggagca tgagtgcaac gcccgcccaa aggatatgat accttttcaa tttataaaat
    76981 tctgttttta caatgcgaac catgtttatt cccccctctg cttatataat ctgtcaatta
    77041 gtaagaacga aaccaatgcc atgatcccaa gaatgaatac aacttgaaat gttgagggaa
    77101 ttagccctgt catttgctcc aagtccattt ttattccatg agccgccata tctcccgcac
    77161 tccaaaatgt agtcagtggc gtgggcagaa gccataacat agttttaggc agtgtgtcaa
    77221 acaatgccgt agcactcatg ttcagaacgc tgtaaaagac acacaacaaa atggaaaaaa
    77281 cataggtctt actgaaaaag acaacaagga caatcaacgg gagtgttcct gccgtaatga
    77341 agatccccgt ttcaaccgcc aaaaacagct tataaccaat tccataaact tctaatgttc
    77401 caattccgca aagaattgtt gcaatggtag aagccacaca aaaaacaatt ccaaaaagaa
    77461 agaggacaat aatctttgca agcaccattt gcgtgctggt tacgggaatt gtacgcagat
    77521 ttttgaatgt atcgttgtcg cgttccataa agaacaggat agcggcaatc actccaataa
    77581 tgcagggcag taaaaactgg ataccatatc ccaacaccat gttaaatagt ccatcgaaag
    77641 catctgcccg atccgtatat cgctccatca tagagggcgt tgtcatcaga taagtcagcg
    77701 ggattggaaa caggaaagca gccagaataa tcagcggaat aaatttcttc cgtttcaatt
    77761 tcaaaaattc gcatttgatt agtttaagca attccttcgc cccctgtcac acgcttgaag
    77821 taatcttcaa gactttcttc acaggtatgt gcttctgata cctccaatcc gttttctaca
    77881 aaggcagtta caattttacc cacaggcaga tcaaggttgt gcaggcgcag attatggtcg
    77941 tcctgtatgg aaaaatggtt ttcatggaaa ttgcgttcca aaattcttgc cgcctgtgca
    78001 gtatccgaaa gcgtaaaacg gatatgctta ctgctttttt gctccagctc ggcaaggctt
    78061 tcttcttcca gcaatgcgcc gtggtcgata attccaatat cgtcagccag caaggaaatc
    78121 tccgaaagaa tgtgactgga aatcaaaatg gtttttcctc gcgcgtcaca aagctcacga
    78181 ataaaggaac gtacttctgc gataccgata gggtcaagtc cattgatagg ctcgtctaaa
    78241 attaaaagtt ccgggtcgtg catgactgca agggcaatcg ccaaccgctg cttcatacca
    78301 agagagtatt gcgaaaacag ctttttatcc ttgtaaggaa gcccgaccaa atccagagca
    78361 tccctgattg catggctgtt cggcactccc cgtagagtag caaaaatacg cagattttcc
    78421 gttgcggtca aattcggata aaagccgggg gactcaatta gactgccaat gcgggggagc
    78481 aacttctttt cattcccttg caaagacttt ccccagattt tgacctcccc ggaagtcggc
    78541 ttcgttaagc ccaacagcat tttcatggta gtggtttttc cggctccgtt tctgcccagc
    78601 agaccgtaaa ttctcccacg cttgacatgg atatttaagt cggccacact cttttgtgag
    78661 ccgtattgct ttgtcagatt ttttgtttca atgatataat ttgtatccat attcaaaacc
    78721 tcctgttctg taaggtattc tatcatgcca accttgcatt aaccttgccg caaccttgca
    78781 ttaaccttgc aatttgaaat ccagtaaaat gacaaaggct cccgccataa agacgggaac
    78841 ccgcttaact ctccaaagga aaaagcaaca taaattcagt tccttttccc ggcaaacttt
    78901 caactgttat acttccaccc attttttcta caagctgatg gacaatagaa agaccaagtc
    78961 cgctgccttt ttcagagcgt cctttatcac acttataaag ccgttcaaat atgtgtttca
    79021 aatcttcttt ctcaattccc actccattat ccgccagcag cagctccatg ttattttcct
    79081 tcttcgatag ggaaattttg attttgtccg catggctgtg agcgattaca ttttgaataa
    79141 ggttattgat gatcctcata tagctatcca tatccaatct tacccggaca ggctgttcgg
    79201 gaatatcaat gtcataatca acctgtttat cctcaaaaat cggtatccag tcgatcagaa
    79261 tatttcttgt cagctctgca acctcaacgc tctggatctc caaagcaaac tcgtttgaat
    79321 ttaacttgaa ccagtcaaag agtacatcaa tgtattcttt cagatcatgg gctttccgac
    79381 gggcggtttc aatataatca tcccggtctt ttcctgtgac cagtcctttg tgtgtagcgt
    79441 caagataccc aagcagagta gtaaggggcg ttcgcacgtc atgggaaagg ctcgtcataa
    79501 gctggcggtt ggtttcttct gtctgccgta cagttgaaag tctgctttca taggccacaa
    79561 cgatctcatt gatttcatag gcaagaggtg ctgtcagttc atttgttgca gatagaatac
    79621 gccggttgcc atttccgttt ttcacatcaa ccagcacatc ggtcatttct gctatttgtt
    79681 tttttacacg ccgaacgaga acgatggaag tcaatacagc cacaacagca atcacaatgg
    79741 acaagaatac gataatttcc atgctgatta cacctcctta ttaaaccggt agccaatccc
    79801 tttgaccgtt tgtatatact ttgggcttga aggattgact tctaattttt tacgaagccg
    79861 actgataatc gccataatgt tactgtcatc atagaaatat tcttcgcccc atacttcctc
    79921 ataaatctgc tgtttggtca aaattttccc ttgatgtttt gcacagtaca ggagcaaatc
    79981 aaattccttt gggggcagtt caaaagtgcc gtttgatgta gtagcagaac gattttcaag
    80041 gtcaatctgc aatccgtcaa aatttagctt ttgtatggct ccagcttgct gattaaagcg
    80101 agtgtagcgg cgaataagag acgcaatacg ggcaatcagt tcatccatat caaacggttt
    80161 tgtaagataa tcgtccgctc cggcccgtaa gccccgtact ttagaaatgc tgtcattttt
    80221 agatgtgaac atcaaaatcg gcaagctgta ctccttgcga atttcttcca gcgtttcaaa
    80281 cccgtccatg ccgggcatca tcacatccag caccacaagc tggtattcct gctctcttaa
    80341 tttttgtaag ccctcttttc cggtattaca aaaatcagct tctatgtttt ctgcttgtac
    80401 gctacgttta atcaaagcgc acagctcttt gtcatcatct ataatcagga ttttattcat
    80461 ggcgcaactc ctttccttgt tttgtccttc cgtcaatcgg cttttccgca tcttttggaa
    80521 ttagccagat agttgccatc tttacagcac caggaatacg cccggcagca caatagtaat
    80581 ttactctacg aggtgtcacg ccccattttt cggcggcctc ttttagtgtc atataatcca
    80641 ttctgcacct ccatagagta tattatagtt ctctttctcg aacaatgcaa ggaacgaaat
    80701 gtgaattata aacttcaacc aacctgcata tagcaacatt ccacgggtga agtatgaatt
    80761 atacaatgta actgggtgat gttatatggc gaaagttgaa gattgtcccg gttttgaaac
    80821 cttcggtgca gatgtcaaag ccgcacgaga ggcaaggcgt ctggcacgaa aaacattggc
    80881 agaaatggtt gggattgaat ggcggtatct tgccaacatt gagaatcaag gtgcgattcc
    80941 gagcctgcct gtgatgatcc aattgattaa ggtctgcgga cttcccgtgg aacggtattt
    81001 taacccggag attatgcgag aagaaagcga acagcggcaa cgggtcagcc acaagctgaa
    81061 gctttgccct gaagaatacc tgccgattat cgaaggtgcc atagacgggg cgctcaaaat
    81121 ggaacagact gcgaagcaga aggaggacgc ataatcgcgg cctccttctg gcatttctat
    81181 atcaaggttc ccggcacttt tccaaaagtt cccgacacct ctgttggatt tctccggttt
    81241 ctgtcacagt caggtcacgg tcatttccag taatcttatc ttccagaaag ttggcgtatg
    81301 tacccaacaa agcgttccgt aaatcctccg gggttttctg tatttcagcg ctgtaccagt
    81361 cattccggtg gggttcccat gccatcaatg tataaccgtg gctggtctga accacctcat
    81421 acagtggatc atcatccaga tatgcctgaa acactttcaa aatcttttca aaggtcagca
    81481 ttttccgcac ctcccattca gctgcaaatc agttccctga ttaaaatttc ctcaatctgt
    81541 gccgttaatg tgttcatcag ccccacccag cgcatagggt cacaggcttt cagttcctcc
    81601 gtgacacccg caacttccat catgtgaggc aacatggttt ccacacgccc ctgtgctgtc
    81661 cgctcaatct ctaacaggtg tggatacagc ttctcgctca tcagcagatg gttgtagaga
    81721 atggggcgat gttcctttag gtaggatttt cgcattctgc cgtacttgcc gatagaagtt
    81781 tccggctgtt cagaaagttt taggttgggt atatcataat ctccacaacg aatgtaagtc
    81841 aacttactca tattcattct cctttgcttc gtgatgatta gactgctgcg ctggctgcta
    81901 tgctgccttt gcgcggttct tcttttggta gctgaccgat agtagaaaaa acaccttttt
    81961 tcatatcctc agcccggatc agggctttct tagcgtccat ttccgctttt ttcttcgcct
    82021 tgattttgtc ctcatactgt ttctgtgcgc cgctggcttt ccgcttcaaa taattctgat
    82081 gaagcctgtc cttgcgttct tcttttttcc gcagttcttc ctgttcctcc ggggttaaag
    82141 gaactggctg taaggatggt gggatatagc gccctaaaaa attgaagtag atttcaattt
    82201 cctgcgtggt gtcctgactg ccttttcggg cgcgttcgtg gacaaggatt ttctctacaa
    82261 actcgttgag catggtgttt gtcagagtgt caaaattctc atacttatca attagggcta
    82321 taaatttctc tgcggatttc tggctctgct catagccggt aacagccttt tccagctctg
    82381 caatttcaat ctcaagtgcg tcctgctctt tggcatactg tgcatcaagc gccttatatc
    82441 gtgcatccgg cagcttgccg agggcgttgt cctcatagat tttgcaaatc agtttttcca
    82501 gttctccggc tctcttttgg gcagcagcca gacgcctgcg ctttttcgat atatcggcac
    82561 tctgttgagc aacctgcgtc tcctgaacag tgtgaataaa ttccgtccgg tcatttctcg
    82621 aatattcagc gatagcccgg agcgtgtcgg aaaccaatgt caggacagca ctctcattga
    82681 tacggtgttg tgtagggcat agtgtcccac acggaacttt ggtataattg gaacaggtat
    82741 attgagaaac ccgcttgcca ttgttggtgc ggtggacata catcttgccg ccgcaatcgg
    82801 cacaatagag caagcctgtg aggggagccg cttcgcccca gccgtttgga taacgccgta
    82861 cattgctgcg gattttctgc gccaaatcaa aggtctgctg gtcgataatg gcttcatggg
    82921 tattctcaaa gatcgtccat tcgtcctcag aaacatagtg gcttttcttg tccttaaagt
    82981 gcttgcgggt tttgaaattg atggtatgcc ctaaatactc tcgttttttc aaaatgttca
    83041 cgatggtaga tgatccccac ccataggggt ctttgaccgg ctttgaacgg ttcacaccct
    83101 cgttgaagcg ggcaaggtgt acgacaggaa tttcaatccg atctgtggat aatttgtagg
    83161 cgatctggta aggcccatat ccctccagcg tgagggagaa tatacggcgt accacttcgg
    83221 cagcttcctc atctaccagc caatgctccc gtttttcgtc ccataagtag ccgtaaatca
    83281 cagtgccggt caggtgcttg ccactcatgc cttttgactt aaacacagat cggattttcc
    83341 gactggtatc acgggcgtaa aattcattca taatgttgcg gaacggggta aaatcgtcat
    83401 cgcctttcag actgtccaca ccgtcgttga tggcaatcag acgaacgcct cgctgccgca
    83461 aaacctccat aacttgaccg accttcagat agtcgcgtcc taaccggctc atgtccttga
    83521 tgacgattgc ctctacacgc cctgcctcca cttcctccat catcgccaaa aatccggggc
    83581 ggtcaaaacg ggtgcctgag ataccatcat cggtaaagtg cgtagggttg ggcagcccat
    83641 tccggcgggc aaaatcctct aacatctgtt tttggttgga tatggagttg ctctcgccct
    83701 gtaactcatc gtcccggctc aggcgctcgt acagtggggt aattttttca tttctcatgg
    83761 ctgtacctcc tgaaacaaaa atgctctaag tgattgcttc actaaccatg acaaaatcat
    83821 gattaagaag tcacttagag catatatcac ccgcagccaa tttgtacttt ttatattgct
    83881 tcactgcaaa gtgtgtaggt tctttcttct ccagtgcttc aaagagccta tctatcggat
    83941 tcatataggt ttcattatct tctctgactt ctgaagcatc aatcatatca agcagagttg
    84001 caaagttctt ttcttctctt ggagcttcat agaagatata gccaataagt gctgtatagt
    84061 agagtttctc agctttcacc caaaaatctt cacctgattt ttctccctct cccttggtgt
    84121 ttgcgataat tgtctgtact aatttgagta tgtccttttc acttctaaga taagcaaagg
    84181 gattgtattt catagacttt ttgaagttaa tggtatttag gatttttatc tcatatccgt
    84241 tatcttcaag catcttaccg cactcaagga ctatagttcc tttaggatcg gtcacacaat
    84301 atgacgagtg catctgcata aggttcggtt ttacataaaa tctcgttttt ccacttcctg
    84361 atccaccgat tacaagtaca ttcttatttc ttgcatactt tggatttgcc ggtctgccat
    84421 tcatggttaa tcgttctgtt tgcgtaagta ggatattgtt ttgaaacttt tcatccatat
    84481 atggctctat atcttttttc gttccccatc ttgctgagcc atactctttc ccctgtctaa
    84541 actttttagc atttttccct ttggtatata cgataatttt gattaaaaca gctactacca
    84601 ctcccattaa aatatccgta ggatgaatgc ttggaagaaa gctcatggtg ttaagttcca
    84661 gtataccttg aaatattttg tctattacat cgccaccagt atatgctctt acatgatgag
    84721 aaaagatatt gccaacatag aaaaatgcaa gatagggaat gttctgcttt agaaactttg
    84781 ccttatcttg caccttaaat aagcctttga tgtcttttag tatcttatct atcataggct
    84841 ttgctccttt tgtttatttt tgattttctc ttttgaaata gagtttttag ccatctcttt
    84901 gaacttctca atattcttgt gaatagattc tttcctttct gctttctttt ctgattttga
    84961 aagagcgtgc ttaaaagctt tatccatcac tttcatatct ttggcttgaa agaatacaga
    85021 gtttttacct gtctctttat ttttcatcac tgaaaattta acaccgtatc tattcaactc
    85081 ttttttaagt tctttaagct cagcttcttc cactgggatt tcttcaagct gtcccttttt
    85141 aaccatatct tttagcttta cttcatttcc gttggcattg accagttttt caagtcctcc
    85201 gaatttctcc gcttctttca tcaatttttt taataagttt aatagaactt ttccagtaac
    85261 tttaccagca tttatctcca tatttaaggt ctttcttgct atttcttcat tgatcacatc
    85321 aatatcctcc tctcatatca tagcttacaa gagccgaata ataggcatct attccacttg
    85381 gtgcattata agcggcggtc aggacaaaag ctcttatatt tctaatccta tattcatttt
    85441 ctcttaatac tcctactaag tactctaaat gtcctgaatt aagtttccta aatctttcct
    85501 ttactacttg tacagatatc tttgtttggt tgatagtaat gaaagattca tcatctaata
    85561 ccattacatc tgccagtatc tttaatattt catcaaactc ttcagccaca ctcttattcc
    85621 caatactcat atgttcataa tatcctgttt ggtgtcgcaa ttcttctaaa caattttgat
    85681 atatattttt atagcttata tctatcctcc ctcccttcat attctctgaa aataattgat
    85741 tcttttcttt gatggaagga tggatggaaa tatatgctga attatttgta gtattatttg
    85801 tagtattatt tgttgtattc tctggtaatg gttggtgcaa attatccttt tgcattagtg
    85861 cattttgaac ctgtgcatta gtgcaatctg cattattgca ttggctgatt ttgcccttat
    85921 ccattggtgc attttgccct aatgcattgg gcatagaatt ttttaatgct tctgtttgta
    85981 ttttttgttt tttcaaatcc atatccatat ataattcttc aagtttatca ttattaattg
    86041 tataccattt tgttttatct cttggatcct tattgtaatt tccaactaaa agataacctg
    86101 ctttttctaa ctttgaaaaa gttcttttta ctgtatcaaa gctcatatag tcaaagtcat
    86161 tttcttgcca tgctcgaatt gaattatatg tccagtattt accatcatga taattctttc
    86221 ctgatttttt atttatttct atccaataat taatctgctg tagtatgagt gcttcgttta
    86281 atcctatttc tctagcaaga gttttattcg caactatagg ttgttcatca aataaataca
    86341 taactcatca aacactcctt tctttttttc aaacaaaaag acgatagtta tttctatcgt
    86401 ctaaaatcat atataaatat cattttctaa atagagcgta ttgcttcttt cactcccgtt
    86461 aaaacggcta taacagctgt tccaaccatt ggtattccgt atgggcttaa caaaaatcct
    86521 aatatcaatg cttctatccc tatggtaacc tctttttgta aaaaagatgc tattgctcca
    86581 aatatgcaaa acatcatcaa caggtaaagt attgctgttc ctatgccaag taaaaatgaa
    86641 agaaatgcaa tgagaatact taacgctata ctaattggaa ataagataat ttttaatatc
    86701 catctcatat atactctcca tttatactaa atcattttaa aatgtcttaa agcgtccatt
    86761 atagcttctt ctttttcagg cgtacactgt gggatagcct gattgtcttt tttagattta
    86821 ttataatgct ctctcagttc aattccacat ttcttcttaa tctgtgcaat ataaagtgta
    86881 gaaaccttta gcccaaattt ttctaataca tactccttaa tttgagcata tgttgctttg
    86941 ctctctgcac ttgtcaaatc aagctcatcc agcttaattt caacatctat atgcttatcg
    87001 acatcaagtt tggacaataa cgctaccgtc tcaaccgtta cagttccagg tataaactct
    87061 aaaccatttg gaattaaatc cctaaaaaat acattagtta aagggctatc acaagtatta
    87121 tctaatgtaa ctgtatatgt gattatatca cctacattag cagtttctgt gttacttgtt
    87181 tttattggag taaaggttgg aacagctatt tctcttaaag aaacatcatc tatagcatag
    87241 tcatttccaa tggcgctttc tccttcacta aaaaattcta ctgtaagttg attattattt
    87301 tgagaattaa tcacagtacc tacttctttc cattctggtg cgtttgtatt aactggaatt
    87361 tgagctccta atgttgcttg atatagtata ttattatttt ggtcaaatat tcttacacct
    87421 agctgtggtg gtggatatcc tgttacctta aaaaggttta aaatccaagt gctaaataaa
    87481 taattagtgt taggtgtaac ttgtactgtt gatttaaaaa atacagctcc aggattaaaa
    87541 ccatttacca ccatcattct tcctgtttca tttcctgtag tatggtcagc aatacgccac
    87601 caagctccta taacattact cattgcattt gtcataatat tttgtactgt atattctcca
    87661 tctaaaggtg taaacttagt tgggtctggt acaacatacg taaaatctgg cgtcacattt
    87721 gggtaaggtt ctatttcagg tcctgtatta cttggtgtac ctggtggaaa aaaaccgaat
    87781 gttccgttat ctgcatctgt aataaggttt atattagata cagacacgca agaatccaat
    87841 atattctcta taggtgtata aatcacaggc ccatttaata tattttgatt tattatatct
    87901 gaacctgcta ctgttattaa tagtgtgtta ggtgttgtac catctaagtt tgttgaacca
    87961 ataggaggat ttgtcacaga actaataggt ggcatttctg caattggaac tggacctact
    88021 atcgctgttg caaaattccc tggtgttggt actcctcctg tagttccaaa agcttctaca
    88081 attctatagt taccatttgg aacattagta aaaacataat ttcctgatgc atctgtgaga
    88141 accacaagtc taactccagt tgctatatct tgtaatacaa ctggtatatt ggctattcct
    88201 gagtccccag aatcaatggt agcacttcta tttctatcaa aaactatttg tcctgatact
    88261 gttgccatat tatcactcct ttgtgattac aaaatttgtg ttcataatat attattcttt
    88321 gaaactcttt tatgtgacat tttaagccta taagtgcgct ttttttctat aacatctaat
    88381 atgtattttt tttatttgca atatcaattt ttttatattt tattgtatat gttaaaaaat
    88441 atcttatgtc ataagttaaa aactatcaaa caatagtaaa tggcataaaa ggtattattt
    88501 tatgccattt ttcaataatc aagtattttc aatgtattta taataacaaa attacaattt
    88561 gtcagtgaaa tgtcagtgat ttttttgtta ttttttactc tttttaattt gagaagatta
    88621 agaatatgct tttatattat aaatcatcaa acaaaatatc gtaaaattta aacttaatta
    88681 cttgagatat tcagagatat aattttttgt attttatttt tatctaattg agtttagagg
    88741 gtctattttt ctcgaaaata acaagctttt atattgcttt ttaaatgggt ttaatttttt
    88801 tcggtgatag tttgtacctt tctaatcaaa tcaagcttaa aatctactta aatacttaat
    88861 ctggcacttt aatctaaaat caataatttt agtttacttt atttttatta tgtaaactga
    88921 aatgtttttc tgaattttat atataatttt gaataatcaa tataatattg taattgtttt
    88981 tatatcaatt tatattagta ttataaatat tttatttata ttcattatat tagtataaga
    89041 tacaaagagg atttaatcat ggaaaaaata atgaattttt taaaagaaaa ctcaacattc
    89101 tattttgcta cagttgaaga taataaacca agagtaagat cattcggatt tataatggat
    89161 tatgaaggaa aattatattt tggaatcgta aaatataaaa cttcttataa gcaattactt
    89221 gtaaatccca atgttgaaat ttctacaaca agtaaagttg gaaaatggat tagaattaag
    89281 ggaatagaaa agactagata tgagtttata tctagtcttt ttatttatta tctatcaaaa
    89341 atgattgttt tccataatgc aaaaaattct cttgtatagt aagttggtac aaatgaaagt
    89401 tttgatttac tagcataaaa agacgtattt ttatatccat ttctatatgc taatatttta
    89461 cttctgagaa catgaaaatc tgttgttact atttttactt ttaaatcact tagttttctt
    89521 tgactatgtt cttctatctt caattttgaa tatttaaaat tctcataagt attcgtggat
    89581 ttatcctctt ctattatcct atttttatct atactatttt ttataagata atctttcata
    89641 gcttttgcct cagttatttt ttctccactt cctttaccac cagatactac cacataacaa
    89701 ttatcattaa tttttaggta tttcaatgca gtgtctaacc tacccttcag ggttgtactt
    89761 ggtgtagtct tttttacaga agctcctaaa attaagagat aatcactttt tgattctaaa
    89821 ctatttttag gataaaaaat aattaaactc tcagtaacta caaatactat taaaaaaatg
    89881 ctgattatta tttttaacac cctataaaaa accttctttt ctttaatttt tttcttaaat
    89941 atttgataga taattagtac aattcctaca actaagaaaa tctcactaaa tgaaattcct
    90001 ccaaaaacta ttttgagata aaaatagtaa attgtaaata ttataccaag tatcaaagtt
    90061 atactattta acatatcttc atagtccttt tttatttatt tttgtataaa gaagaatcta
    90121 tacactctat aagacagttg tattctccat ctatgcaatt aatccaactt gctatactga
    90181 tatttttacc aaatgtattt gtctctattt tgaattttga atgcttattt tcttctaatc
    90241 cgttaagagg gcaattatta catggtctct cagattttaa tagtgattta taacaggttt
    90301 ctcctaattt tatctctaaa tccaaacgag acaccttatt attgacaaaa agaagttcat
    90361 aagtatttgg attcactata taaatataat tatcaataga atcaagaatt tctttaagta
    90421 ctggtttgga tttctcacat ttatttgcta attttatatt attatcactt atattatttt
    90481 caagttcatt ttggtagata caattattat aaagtgcata cttatctttt cctttgctct
    90541 ttgcataata aagtgctatg tctgcttttt tataaagttc ttcaaataca gttccatgtt
    90601 ctggtacaaa tgaaattcca actgttccag atattttata tgtcttttta ttttccgtat
    90661 aagaatttct aaatatatcg catatttttt ctgctttctt tttggtattc tcaaaagact
    90721 gaatattttt taagaatact ataaattcat ctccaccaat tcgacctact atatcatctt
    90781 ttctaaatat aggttttagg tgtttagaaa cttcaaataa tactttatct ccaaatacat
    90841 gtcctaaatt atcatttaca gatttaaaat tatctatatc aacaattaaa aatgcatgca
    90901 ttcctaagct tgcttcgtca gagttcaaga aatcattaat caaattttct gtagtacctt
    90961 tattatataa tcctgtaaga gtatctcttt cagcttttaa ttttaattta atttcttcat
    91021 ttttttgctt gtcaatatct ttaacataag caagtgcttt tatatcattc gtaatagaat
    91081 cttttattaa gtgcattgtg caaatgaccc aaatcatttt attttcttga ttcattcttc
    91141 gatattctaa ttttatttca gttatatttt tgttatatgc agataataaa tttttacaca
    91201 aaaatgtatt taaaaacacc tctttattgt ctttgtgaat aatactgttt gatatagttt
    91261 ttaccatttc agaataatta ttgtcaggct taattccaaa tggtttttgc caactttcat
    91321 ttcctttgat aaaagtatct tttgatacat ttatttcata ggttatcatt gcttccgaca
    91381 atatagctga atgatactta ccttcttgat tatatcttat ctctgcttcc ttttgtttgc
    91441 ttatatcttc ctgtatacca attgctctta caggattacc atcttcatca aaaatagtag
    91501 tcaaggtaac tttattccat atataatttt catctggaag tttcatctta actacacaac
    91561 ttgctttttt tgctccattt attacatttt catacatgtt tataaaatca tcactaaaat
    91621 ctttatgaat aactcctgat tctactagag aatatggaac gtttttagta attttataaa
    91681 tattatattt atcaagctct ttactagtat ttaaaagtga ctttgttttt atatcatact
    91741 caaatatagt atttgatgtt tgctttaatg caattctaaa tctttcttca tttattttaa
    91801 gtttttgttc tgcatttttt aaatctgtta tgtcatttag aatccaaata cctttttcaa
    91861 taccatcatc atcaataata agccttcctt ttatagaaac ccagataata ttaccatctc
    91921 ttcttcttat tctatgttga tatacagcta ttccttttgt gtttaattga tgttgtatac
    91981 tttcaagagc cttctttcta tcttcataaa aaacaagatt acaagctttg tatttaagtt
    92041 cattttctaa ttgttcacgt gtatatccaa tcattgaaag ataaccagag ttagtgtatt
    92101 ttatagtaaa atcatcatta aattctgtta taattatacc acctaaaata ttttctgata
    92161 tcatttcaag ttctagattt ttttgttcca tctcttgttc taattgtttt gttctagtaa
    92221 tatctacagt tacacaacaa aaatattctt ttccatcagg ttctgttata agttctcctt
    92281 tatctaaaac ccatactgta ttaccatttt ttgttataat cctatattct aattcaatag
    92341 ttttattttt gtaaagttgt ttagaaattt ctttttttat tctttcaaca tcatctttat
    92401 gtattaaact ataaaaatca ttattaaaca atgtttttat ttcttctctt gtataaccaa
    92461 acaactctat aaatccatca cttaaaaaat taatattgca tgtttcaccc agggtacact
    92521 tttgtactcc tccaggaatg ctatttgtaa tagatgagat ttctttgtta gcttttagta
    92581 tatctttctg agatttattg tttttataaa taatatatat tataagcata ataaacaata
    92641 agaatacttt gaaaataaga gaaaatgcta attgatttat tttatcaatg tttcttctta
    92701 cagtatattg tggtatcaca gaaattacat accagtcatt tacaccaatg ggtgtataag
    92761 tagcataacg attttctcct ttgtattcat atgaggtaaa gccactcttg ttattttttg
    92821 tatcttcata tattttttta tagctataac catcatcaaa agaagctttt ttaaatatat
    92881 catatatgtt actacttgac ttaatcagtt tgtttgtatg tgaagatttt aaaacaaatt
    92941 gaccactaga ttcaaatata tctatgtacc cttcactatt aaaacttgtt atatctataa
    93001 attcagctaa tttatcattg tagtaagaac cgtataaaac accaattatt ttgttattct
    93061 tattaaatat aggagtagct ataacaaaag tatcttttcc atcaattgga gatttcacaa
    93121 cttcagatat attgctttct cctttaatag ctttcttaaa atactgatat tttgacacat
    93181 tgataatttt gccatcgctg gtatgactta ttccatcagg agatacaata gagattcttt
    93241 gaaagtcaga ttcttttgat atgttagcta ataatggaac tatttttgag ttatctatag
    93301 tattaaaata agaaaccata tttgccacac ttttaataaa ggatagagaa ctatctaatt
    93361 ttatttttat agcattggaa ctttgtaggg atatttccct taaattaatt ttactatttt
    93421 cttcttcctg gacattagtt ttaaatgcaa aatcagaaaa agaaattatt gtaaataaaa
    93481 atattaaaac aatactcagt acatttttta acgattttgc tcttatcact taatcaccac
    93541 ctcccattta agactcgctg actatatttt atagactaat ttttcaaatt ctttaattgg
    93601 taatggtttt gaaaaataat atccttgaac aatatcacaa tttgcttttt ttaacatttc
    93661 tatttgactt cttgtttcaa ttccttcagc aacaaccctt attcctaatt gcttaatgag
    93721 agaaactatg ctttttataa caatttgact cttatcaaca tctttatcat caacaaaaaa
    93781 tcctctatct aattttatta catttaatgg tatattttta agcatattta cagaagaata
    93841 tcccgagcca aaatcatcca ttgcaactat aaaaccaata tcctgtaggt ttctactaac
    93901 attaaataga gtatcagtat ctccaaacat actagattca gtaatttcaa tttctattaa
    93961 actatatggt attttatatc tatcacatat atttactatg ttttcaataa aatctttttt
    94021 taaaaaatca actcttgaga agtttacaga tataggtaaa ggtgaaattc ctttatcaaa
    94081 taaagaccgg atttctttac aagcttgttc taatatgtac atatcaattt ttctaataaa
    94141 tccatttttt tcaaatatag gaataaaatc acctggatat atgacttctt tttctgtata
    94201 ttgccatctg actagggctt cacttccaca aaatttatct aatttaatat tatattttgg
    94261 ttgtaaatac attacgaatt gcccactttc aagagcatat tccatttctt tttctatctt
    94321 atcttcaagt aataatttct ctcttaattt atcattaaaa aatgcaaaat ttacatcact
    94381 attatttttt attgatgatt ttgcaagtga agctctatca ctatatacac ttacagataa
    94441 atccttatct ttgatttcat aaattccaaa agataagttt acaagttcat tatttgctat
    94501 aattttttta ataatattta ttatatcctc ttttttgtta tatgttaata atatattaaa
    94561 attatcagca cttacacgag caaaagtttc attgatatta gtcaattcat ttaaagtatc
    94621 tgcaatatct tttaatatta aattgccctt tttatgtcca tatatatcat taattgcttt
    94681 aaatttatca atatcgaata tgaccattgc atatttatta ttttgtgatg ttttctttaa
    94741 taaatttgta acatctaatt caaactttct ccagttggaa taacctgtta caaaatccgt
    94801 atatgctact ttttctatag ttttttgact ctttgctttt gaatataata tgtaaattat
    94861 aatacataaa aataaaaatg aaagtataat ccatccagta attgtaactg tcattatgtc
    94921 atttgtttca tattctaata ctctactaat attacctata taaaagaatg taaatacact
    94981 aaaaaagaat agtactataa atgctattga tatattcttt attattaatc tatttttttt
    95041 caaatagcta cacctcactc tctttagcaa ttataatata attgattcac tttattttac
    95101 tattaataag tattttttac aattaagttt tataaattgt taataaagag catttaaata
    95161 aatatcatta tcatttaaaa gataacaata gttaagggta caaatatatc aatagcatat
    95221 ttaattatat tgaatccata tttattaata caattaaata cactatcgct tacatttata
    95281 cccatctata tatagcttaa atattaatat ttatttttct aaagcttctc ttcttattga
    95341 tgatttttta aaatactcta tcaatttatt tttatcattg ttaaatatag cttcttttac
    95401 taaatttact tctgattcaa agttttctat aacttttagt aaattatctc tatttcctaa
    95461 aaaaagttca ctccataagt cttcattcat atttgcaatt ctagttaaat ctctataact
    95521 atctccaata aatttacctg tatctctacc ttcttcatca ctatttataa gagcaactgc
    95581 cataacatga ggtaactgag aagtaaaagc tataatctca tcatgttttt gtgaagttaa
    95641 cttttttact cttttaaatc caatctctaa aattaaattt tcaactaact ctaaattttt
    95701 tatgttgttt ctgccagttg gagtaattat ataatttgcg ccattaaaaa cttgttcact
    95761 tgcaaaatca ataccctttt tttccctacc tgccattgga tgtccaaata taaaatctat
    95821 atcatctgga ataatttgca acacatcatt gataagtgtt tcttttattc ctgtagtatc
    95881 agtaattata gtcccttttt taaaaaagtt tttattatta tttagaaaat ctacaactaa
    95941 tctaggatat atagatagta taattaaatc agctttttta aataactctt tacctgtagt
    96001 acatcctttt tttatgattt ttgctttttc tgcttttttt aaagtttcta aatctacatc
    96061 tactccaaat acattttcat atccagcttt ttttaatgct ttagcaaaag agcctcctat
    96121 aactcctagt cctacaataa caatattcat tatttttatt tccccctaga ttatttttct
    96181 ttaaagtcaa atttaaaatt ttcactgact gcatttgtaa tattatatac agcattattt
    96241 aatgatttat catttaaaat ctctatatct gaaaattttt tataaagatt tattctctca
    96301 ttataaagat tatacaatct atcttttccg ttttttaata atggtcttga attaatattt
    96361 atatcttcca aaatcttttg tataggtcta tcaataaaaa ttattatacc tgtttctttt
    96421 agtatttcca tattaacatc cttttttatt acacctccac ctgtagatat cactgtttta
    96481 tcacttatag aaagttctct acatgcttga gtctcatagt tcctaaagat atcttctcct
    96541 tctgaaaaca actctgctat acttttttga gatatttgaa ttatataatc atccatatca
    96601 cagaaactac aattatattc tttggccaaa agtttaccaa ttgtagtttt tccactacct
    96661 ggcataccta ttaatatcaa tttttctttt gttttattta tcatgacaat ctcccttaca
    96721 aaaattctaa ttttagttca ttatatataa catctaaaat actattatct attttagtat
    96781 cttgccaaat ttcctgagat tttattgctt gccctaccag catatataat ccatcacaag
    96841 tttttttacc catactatta ccaattctta aaaactctgt ttctccagga ttgtaaatta
    96901 aatctattaa tatatcaaaa ttttgtataa tagattttga cactggtgaa attcctacat
    96961 tagggtacat acctactggt gtagcattta atattatatc tccttttata tgtttaagtt
    97021 cttcataatc tattaatata gctttactat ttaataattt tttatcatcc ttttttctag
    97081 ttgaaacata aagcttttct ataccagaat caataaaata tgtaagagca gctttagaag
    97141 cacctccagt tcctaatata actgctactt ttccttgaac atcaatatta gccattttaa
    97201 acatactatc aagaccaaag taatctgtat tgtaaccata taacatattt tctctgagta
    97261 aaattgtatt aactgctcct atacgttttg cctctggtga tataaaatca agatatttca
    97321 taatacgctc cttatatggt acagtaacat ttactccttg tattcctaat aattttatag
    97381 caccgtctag cttagatata tcttcttttg gaatttcaaa gtttttataa gcactttcaa
    97441 tattcaatat ctcgaatatt ctcttgtgga tttgaggtga aacactgtga gagagttttt
    97501 cacctactag accgaaaaaa ttcatactta cacctcctaa taattataaa ttaaataaaa
    97561 atttatatta tctattcagt tttattttta tatactccca taaatttaaa atatgctgta
    97621 ttatgttcta tcaattctaa taagtcgtac actttagaat tgtatataga acactcaaaa
    97681 tctatataaa agaaatatct ccatgaggca tttttcatag gtcttgactc tatttttgtc
    97741 atatttatat tattttcagc aaagtatcca agtactttat aaagttttcc tgcttcatgt
    97801 tcaacagaaa atactacact cattttgttt gattcttctt caatgtgtat ttgattactg
    97861 attactacaa atcttgtata gttgtttgca atatcattta tacaaggact tattatttct
    97921 aattcataaa tacttgcagc ttttttgctt gcaattgctg cttttgtttt atcttgaagt
    97981 tttcttacaa gttctgcact tgttgctgtg ttattaaatg gtatcaattt ccatgtacta
    98041 ttttgtttta aaaattcact acattgtcct ataccttgtg gatgagaata tatttctttt
    98101 atatcttcaa gttttgtgtc ttttatccct attaaatttt ggtctatttt tatacattct
    98161 tctccaacta tataaaaacc gtactttctc aaaaggtcat aagtttcaga gatagctcct
    98221 gtagatgaat tttctatggg gattattcca tagtttattt ctttattttt aagtgctatg
    98281 aaaacatctt caaattcttt aaattgtttt tttgatattg ttttgttgaa gaatttattt
    98341 agtgcttctt ctgtaaatga acctgatttt cctggaaatc ctactaggat atttttttta
    98401 tttaattcat cttttaaaga cttatattta tttacatttg acaaatcaaa tttcttattt
    98461 gatgaatcta aactaaactc gattttctgc tcaccatcat tatctatcaa tcttttttgt
    98521 aatcctctac taatttccat tatagaatta aaaaactgta ccgtttcttg tgagtatgct
    98581 ttattatcta aattatctat ggctctactt agtacttttt cttctctatc tttttgaagt
    98641 atagtagtgt tatttttcat tttatgtctg gcaatttcaa gaactgtatt cattctcttt
    98701 tcaaataatt gaataatctc tttatctata ttgtcaatct catttctata tctcgttaaa
    98761 tcctccatta ttatcgtcct ttcatcaaat caaaaattcc aatggctgtt actgcttcta
    98821 ttacaggtat agccctttga actatacaag ggtcatgtct gcctttaata tataaaatat
    98881 cgtccttttt atcttttata ttaactgtgt tttgttgtct gctaattgaa ggagttggct
    98941 taattgccac tttgaaaatt attggcattc cagtagtaat ccctcctata atccctccat
    99001 tgttatttgt tttgctctta acttgatttc cttcataata catttcatca ttactttgag
    99061 agccatacat atctgcaagt tcaaaaccta aaccaaactc tacacctttt acggcaggaa
    99121 cagaaaacaa taaatgtgat aaagtagatt caacagagtc aaaaaatgga tttccaagcc
    99181 ctacattaat acctactact gcacactcaa ttataccacc aactgaatct ctttgatttt
    99241 ttgcatctat aatcgtattt ttcatggctt cttcctttga taaatcaagt aaaggtagtt
    99301 ccaaagtttg caaatttgat aactgttgtt ttgaaatatt tacataatca aaactcatat
    99361 cttctatatt tttaattttt tttatgtgtg ctcctatctc tattcctttt tgtgataaaa
    99421 tttgtttaca tatagcccca caaaatacta atggagctgt tatcctacct gaaaaatgac
    99481 ctccccctct atagtcatta aatccagaat atctcacatt acctgtgaaa tctgcatgtc
    99541 ctggtctcat taaattttta agctctccat aatcttttga acgagtatca ctatttctta
    99601 tgattgcaca taatggcgtt cctgtagttc ttccattaaa atatccactt agaatttctg
    99661 gtatatcact ttcatttctt gaagtagata tagaattttt tccaggtgct cttctcttca
    99721 tttctttatc aatcttatca aggtcaagtt caatccccga aggaagacca tctatattta
    99781 tacctatagc atttccatga gattctccaa aaattgatac ttttaaatta tttccccata
    99841 ttccactcat caattcgacc tcctaacatc ttaaaatctt taaaaaaatg tggataagat
    99901 tttgatacac actcaaaatc ttttaatatt attggtttat cacatctaca agaagcaatt
    99961 gcaagtgtca tagcaattct atggtctttg tgactccaca cctctactcc accatttaac
   100021 ttgcttactc cttcgattat caaactatcc tctttctcct ctatatttgc tccaagttta
   100081 cttaactcaa catttattgc atgaagtcta tcacattctt taattctaag cctaccagca
   100141 ttaattattg tagtcctccc tatacttaag gatgctacta cagataatac aggtattata
   100201 tctgggcatt gagatgcatc tatcaaagta ctatttaaac catttgttat tccttttatt
   100261 ttgttgcctt ctcttaatat ttccattccc atcctagata aaatttcaac tacttcacta
   100321 tccccttgaa gagaatcttc tttaaggtct aatatgctaa tatcttctcc tatagcatct
   100381 gctgataaat aaaatgctcc ttgagaataa tctccttcta ctttataatc tctcgcttta
   100441 tacgtttgat ttccttttat aataaattct ttatagttat tgtttataat ttctacccca
   100501 aaatctttta tcgttgaaag agttaaatct aaatatcctt tagattctag ctcagtagta
   100561 attattatct ttgaatcact ctctagtgta ggcaatataa acaatagacc tgtgataaac
   100621 tgagaactta tatttccttt tactctaaat tcatctggtt taagcttacc tgatataatc
   100681 aaatctaact gattttcttt gtaactatat tttatattct gtctgtcaaa tatctcataa
   100741 taagtatcaa gtggtctttt tccaagatta cctctaccta taaacctttt tacaccatca
   100801 aatgctaaag atataggtac taaaaatctt aatgtagagc ctgattcatt acaatctatt
   100861 gtcaatttag gttgattcaa ctgattctct ctatttaaaa taccttcttt agaaaaaatt
   100921 cccgaaattt ctaaaatatc ttctttcttt tctataatag ctcctaatga tgtcattgct
   100981 cttatagtag ctattatatc atcagaaaaa tctatattag aaattctact ttttccattg
   101041 cttagagatg aacaaataac tgccctatgt gccatacttt ttgatggtgg tatttttaca
   101101 tctccagata atttacttgg atatattttt agacttccca ttatcttacc tcctgaaaaa
   101161 atttagaagt agtattatat ataatactct ctccaatatc ttttaaaagt attattttta
   101221 atgtatcacc tagatttttt ttatcaagag atatagcatc tactatagat ttattatctc
   101281 ttaattcaat ctcataaggc aaattataat tcattaaaat tgattttata agttctgatg
   101341 tacctttttt tgtaattcct atcttttcac tttctaaagt tatcttatac attcctatgg
   101401 caacagcttc tccatgggta taacccgtaa aattgtagta tttctcaata gcatgaccta
   101461 atgtatggcc aaagtttaga agcattctat ctccaaagtc tttttcatca gcttcaacta
   101521 cagttttttt aataaagcaa catttatgta taatgtattc tatatgttgc attacttctt
   101581 ctctattttt taaacttaaa agtttattga aaaaagtttt gtcttttata catccatatt
   101641 ttataacttc tgccattcca tctctataga atttttctgg aagtgataat aatacatttg
   101701 ggtcgataaa cacagctttt ggttggtaaa agcttcccac taaatttttg cctctctcaa
   101761 ggtcaactcc aacttttcca cctacagaac tatcaacttg tgctaataaa gatgttggaa
   101821 tttgaataaa acttatacct cttaaaaaag ttgctgctgc aaatccacct aaatcaccta
   101881 ttacccctcc tcctaaagta ataatcaaat cttttctagt taacttaaag tcaagtaaac
   101941 tatcgtatat tttaggaaga gtattaaatg attttgtttc ttcaccagat tttaatatta
   102001 aagatttaat ttcaaatcca gattcactta aattattttt tactttatcc aagtataatt
   102061 ttgctatatt ttcatcagtt acaataaaaa tcttatttcc aaaatatatt ttttttattt
   102121 cttctcctat attctttagt atattttttt taataaatat attgtagcta ttttctttta
   102181 aatttactaa tagtttttct tccacgttta accatccttt tatagattat atttctctac
   102241 caactgctga tgcgatagtc tttaattcac ttatcaattc atcatattca tttggcttaa
   102301 tcgattgttt tccatcacaa agtgcatgtg ctgggtcatt atgaacttct attattagac
   102361 catctgctcc aactgcaatt gctgccttag ataaagagtc aaccatccat gatttacctg
   102421 ctgcatgact tgggtcaact ataactggta aatgactaag tttcttcaca gctaaaattg
   102481 cacttaaatc caaagtattt ctagtatatg tttcaaaagt tcttatacct ctttcacaaa
   102541 gaactacatt ttcatttcct ccagccatta tatactctgc tgacattagc cactcttcaa
   102601 ttgtagcaga taatcctctt tttaaaagta ttgttttatt tgttttacct aattctttta
   102661 ataaatcaaa gttctgcatg tttctagctc caacttgaat tacatctaca ttttcttcaa
   102721 atatatctat atcttgtgtt gacattattt ctgtaactat aggaagccct gttttttctt
   102781 ttgctttttt taataaatcc aatccatcat atttcaatcc ttggaaagcg tatggtgatg
   102841 ttcttggttt gaatgctcca cctctcaaaa atcctgcacc tgattttttc acatctttag
   102901 ctatagatac tatttggtct tctgtttcaa cagaacaagg cccagctatc atagcaattt
   102961 tctttgaacc aatttccatt ccattaacat ttatgattga aggttctgga tgaaattttc
   103021 tattggcctt tttaaaaggc tctactacat gcataacttt ttcaactatc ttatttgctt
   103081 ctattctttt ggcatctatt ttactagtat ctccaactaa acctaaaaca gttaattctg
   103141 ttccatctat gggattaact tctactcctt ctctcccaat agcctcaatt aattttttaa
   103201 cttcattttt atctgctccc atttttaata ctactatcat ttttactacc tcccaatatt
   103261 ataattttat atttaaaata aaaaagagaa ctcactaatg agttctctaa aataatctat
   103321 caagcactaa atcttatata aatatataaa ataatcattt ttataaaatt tacttatgct
   103381 caaaatcact aaaataaggc ctcaccagaa aggaagtaca tatatttttg taaaagaaat
   103441 agccagcgct aaaataaaag ccccagaaca taaagtaaaa aaagctataa agttttgctg
   103501 ttagttcttt taatattcct ttcatagtat tatcctccat ttttataatt tattattctt
   103561 cttgtttaat aa
//
LOCUS       DAEQJM010000004       100791 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.004, whole genome shotgun sequence.
ACCESSION   DAEQJM010000004 DAEQJM010000000
VERSION     DAEQJM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 100791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100791
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.004"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(806..1315)
                     /locus_tag="KRQ43_000350"
     CDS             complement(806..1315)
                     /locus_tag="KRQ43_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH2740724.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLSEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            complement(1526..2935)
                     /locus_tag="KRQ43_000351"
     CDS             complement(1526..2935)
                     /locus_tag="KRQ43_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740725.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDMDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDVEIDYSP
                     ERTHDIWDESNEIDKNTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKAEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(2939..4069)
                     /locus_tag="KRQ43_000352"
     CDS             complement(2939..4069)
                     /locus_tag="KRQ43_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2740726.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLRESIDEPIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEGFVKSYFESYSLIRG"
     gene            complement(4081..4884)
                     /locus_tag="KRQ43_000353"
     CDS             complement(4081..4884)
                     /locus_tag="KRQ43_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740727.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            complement(5266..6147)
                     /locus_tag="KRQ43_000354"
     CDS             complement(5266..6147)
                     /locus_tag="KRQ43_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HBH2740728.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSNKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            6603..7577
                     /locus_tag="KRQ43_000355"
     CDS             6603..7577
                     /locus_tag="KRQ43_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740729.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYKLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNHPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(7693..8724)
                     /locus_tag="KRQ43_000356"
     CDS             complement(7693..8724)
                     /locus_tag="KRQ43_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH2740730.1"
                     /translation="MKKIRKLATKLLITTIVLVSGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNNKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPTVGAVAQTQKPALPGKHTMLPHQDGAK
                     VVGKFGDIKDKHVMYEGVRCVVINSSVNTVTFLGSKSNLDPSNLTIAVIGFMNTPYGM
                     FALAPEGEPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIEITDEKANIGL
                     GQIMYIRYE"
     gene            complement(9336..10187)
                     /locus_tag="KRQ43_000357"
     CDS             complement(9336..10187)
                     /locus_tag="KRQ43_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH2740731.1"
                     /translation="MSCILKLKQIFEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(10204..11124)
                     /locus_tag="KRQ43_000358"
     CDS             complement(10204..11124)
                     /locus_tag="KRQ43_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HBH2740732.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDGIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(11234..12148)
                     /gene="murQ"
                     /locus_tag="KRQ43_000359"
     CDS             complement(11234..12148)
                     /gene="murQ"
                     /locus_tag="KRQ43_000359"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBH2740733.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNRVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(12247..13344)
                     /locus_tag="KRQ43_000360"
     CDS             complement(12247..13344)
                     /locus_tag="KRQ43_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH2740734.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDMGFT
                     GSEKALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLTGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFDFKPSTK"
     gene            complement(13577..14923)
                     /locus_tag="KRQ43_000361"
     CDS             complement(13577..14923)
                     /locus_tag="KRQ43_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2740735.1"
                     /translation="MLDKFTEFLDSKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(15012..15320)
                     /locus_tag="KRQ43_000362"
     CDS             complement(15012..15320)
                     /locus_tag="KRQ43_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2740736.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEASVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(15581..15970)
                     /locus_tag="KRQ43_000363"
     CDS             complement(15581..15970)
                     /locus_tag="KRQ43_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740737.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSNKNTKKEMEKNQRTDYNIPTISFK
                     SGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRGFSL
                     GFFRLYILFVLSFAIIGYFWIYKGIHI"
     gene            complement(15972..17132)
                     /locus_tag="KRQ43_000364"
     CDS             complement(15972..17132)
                     /locus_tag="KRQ43_000364"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBH2740738.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAIIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDKNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGVHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(17562..18581)
                     /locus_tag="KRQ43_000365"
     CDS             complement(17562..18581)
                     /locus_tag="KRQ43_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2740739.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDILKNRYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYINLYNCIENSGEIDSYLIDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDDYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSKIGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(18581..19255)
                     /locus_tag="KRQ43_000366"
     CDS             complement(18581..19255)
                     /locus_tag="KRQ43_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740740.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFMDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIDILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYII"
     gene            complement(19407..21314)
                     /locus_tag="KRQ43_000367"
     CDS             complement(19407..21314)
                     /locus_tag="KRQ43_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH2740741.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSLIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKHIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEVKTKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMNDLSGIYILSLVICLIIFVIYGAVS
                     VNKFKSVVYKN"
     gene            complement(21315..22067)
                     /locus_tag="KRQ43_000368"
     CDS             complement(21315..22067)
                     /locus_tag="KRQ43_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2740742.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFIAIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPAVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(22385..23539)
                     /locus_tag="KRQ43_000369"
     CDS             complement(22385..23539)
                     /locus_tag="KRQ43_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2740743.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMILSLFGCLAYGLIVLLNYLQE"
     gene            complement(23542..24009)
                     /locus_tag="KRQ43_000370"
     CDS             complement(23542..24009)
                     /locus_tag="KRQ43_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH2740744.1"
                     /translation="MFFKRKKEASTINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(24023..24511)
                     /locus_tag="KRQ43_000371"
     CDS             complement(24023..24511)
                     /locus_tag="KRQ43_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740745.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(24525..25856)
                     /locus_tag="KRQ43_000372"
     CDS             complement(24525..25856)
                     /locus_tag="KRQ43_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH2740746.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARILGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMIEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(25870..27435)
                     /locus_tag="KRQ43_000373"
     CDS             complement(25870..27435)
                     /locus_tag="KRQ43_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH2740747.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFLFTFLIKKFDMKTPGREEDNEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKVVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(27604..28389)
                     /locus_tag="KRQ43_000374"
     CDS             complement(27604..28389)
                     /locus_tag="KRQ43_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH2740748.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(28556..29755)
                     /locus_tag="KRQ43_000375"
     CDS             complement(28556..29755)
                     /locus_tag="KRQ43_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HBH2740749.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(30277..31614)
                     /gene="xylA"
                     /locus_tag="KRQ43_000376"
     CDS             complement(30277..31614)
                     /gene="xylA"
                     /locus_tag="KRQ43_000376"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBH2740750.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNVTDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(31710..33260)
                     /gene="xylB"
                     /locus_tag="KRQ43_000377"
     CDS             complement(31710..33260)
                     /gene="xylB"
                     /locus_tag="KRQ43_000377"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBH2740751.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNIIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYINTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYKIYHRLYKRIYKSLKDDFKLLDE
                     VVNTKINN"
     gene            33468..34628
                     /locus_tag="KRQ43_000378"
     CDS             33468..34628
                     /locus_tag="KRQ43_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH2740752.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(34784..35188)
                     /locus_tag="KRQ43_000379"
     CDS             complement(34784..35188)
                     /locus_tag="KRQ43_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2740753.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANDDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(35209..35691)
                     /locus_tag="KRQ43_000380"
     CDS             complement(35209..35691)
                     /locus_tag="KRQ43_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2740754.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(35711..36520)
                     /locus_tag="KRQ43_000381"
     CDS             complement(35711..36520)
                     /locus_tag="KRQ43_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH2740755.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(36513..37292)
                     /locus_tag="KRQ43_000382"
     CDS             complement(36513..37292)
                     /locus_tag="KRQ43_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2740756.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(37292..39370)
                     /locus_tag="KRQ43_000383"
     CDS             complement(37292..39370)
                     /locus_tag="KRQ43_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBH2740757.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(40161..40682)
                     /locus_tag="KRQ43_000384"
     CDS             complement(40161..40682)
                     /locus_tag="KRQ43_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH2740758.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAINLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFNEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLE
                     IPIVGFDELREDK"
     gene            40848..41414
                     /locus_tag="KRQ43_000385"
     CDS             40848..41414
                     /locus_tag="KRQ43_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH2740759.1"
                     /translation="MDTKKVTFSSICIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(41631..43694)
                     /locus_tag="KRQ43_000386"
     CDS             complement(41631..43694)
                     /locus_tag="KRQ43_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HBH2740760.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFND
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDVYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(44075..47410)
                     /locus_tag="KRQ43_000387"
     CDS             complement(44075..47410)
                     /locus_tag="KRQ43_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH2740761.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEKLRKSLTEKRKVNTVNYDFKIDEVNEFETRKRYINIELKLAGWE
                     FGKDIGEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGKYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMVTAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRKLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(47460..47888)
                     /locus_tag="KRQ43_000388"
     CDS             complement(47460..47888)
                     /locus_tag="KRQ43_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740762.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(47878..48258)
                     /locus_tag="KRQ43_000389"
     CDS             complement(47878..48258)
                     /locus_tag="KRQ43_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBH2740763.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(48291..48599)
                     /locus_tag="KRQ43_000390"
     CDS             complement(48291..48599)
                     /locus_tag="KRQ43_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740764.1"
                     /translation="MNQIELDLYHDMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(48632..49816)
                     /locus_tag="KRQ43_000391"
     CDS             complement(48632..49816)
                     /locus_tag="KRQ43_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBH2740765.1"
                     /translation="MVDEAKILDVVSISRENVKKFDGERSYLSTGNLDFNKISNLEIV
                     TYENKPSRANQTVNIGEVIFAKMKDTKKTLVINKTNKNIIVSTGFYVLKPSKEILPQY
                     LYHYLNSSYFLNQKNRLSKGATQSALNNEGLANIKIRMYNLKVQEKVVRVLDKAQELI
                     DKRKEQIEVLDELVKSRFIEMFGTPSKNEKNWEISEIGKYLDVLTDYHSNGSYETLRD
                     NVTLLDTKGYALMVRTTDLENNNFEKGVKYIDEHAYNYLEKSKVFGGEVIINKIGSAG
                     KVYLMPFLNKPVSLAMNQFMLRFNEDKVNHIFLYNLLLTSYMESKIKEKVRGAVTKTI
                     TKDAVRKINIIVPPIRLQNQFANFVKQVNSLKFEMETSLKELEDNFNSLMQKAFKGEL
                     FN"
     gene            complement(49820..51283)
                     /locus_tag="KRQ43_000392"
     CDS             complement(49820..51283)
                     /locus_tag="KRQ43_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBH2740766.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFEKIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KESAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVKVLEKEIVDGLEELERMLEV"
     gene            complement(51793..52662)
                     /locus_tag="KRQ43_000393"
     CDS             complement(51793..52662)
                     /locus_tag="KRQ43_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH2740767.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIGTVKC"
     gene            complement(52682..54598)
                     /locus_tag="KRQ43_000394"
     CDS             complement(52682..54598)
                     /locus_tag="KRQ43_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBH2740768.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDGHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMISATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(54601..55521)
                     /locus_tag="KRQ43_000395"
     CDS             complement(54601..55521)
                     /locus_tag="KRQ43_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBH2740769.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(55623..56375)
                     /locus_tag="KRQ43_000396"
     CDS             complement(55623..56375)
                     /locus_tag="KRQ43_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH2740770.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(56672..57289)
                     /locus_tag="KRQ43_000397"
     CDS             complement(56672..57289)
                     /locus_tag="KRQ43_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740771.1"
                     /translation="MNVIKKFIFVILIINILGCGISLILQSSLGSDAITLLNEGIHIK
                     LGISYTIAGLIYNGTLLLIALLLNKKSLGLGSCVYVLVAGIFIDLYIYLLLDFNISSL
                     GIIIRIMSFIIGHILMCSGFAMLIKFDIGMSPLDAILIYIEGKFKYPYKVLKTIADLI
                     FLILGVYLGGNLGFGTIFSILCTGTTISIVSKMISVNKKRYYSSI"
     gene            complement(57377..58834)
                     /locus_tag="KRQ43_000398"
     CDS             complement(57377..58834)
                     /locus_tag="KRQ43_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH2740772.1"
                     /translation="MIKLSKFPKDFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKHYESDMTVDKIKFAMKDNNGYYPKRNGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKDKVKYWIVINQINLMYHESFNSVAFCVDQVDDVEEAKYQ
                     AIHHQFMATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRIQYFFT
                     DVSFRGEYPAYIKRFFKENNINIVMEEGDDKVLKENTMDFLALSYYYSTTVSASKNTM
                     NPIDNVKNQYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYKNVIRTNGEELKEKVDSF"
     gene            complement(58856..59209)
                     /locus_tag="KRQ43_000399"
     CDS             complement(58856..59209)
                     /locus_tag="KRQ43_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH2740773.1"
                     /translation="MTTEEHVIDEELVEVAMQIILRAGEARTEIKHALNDLERFDYKN
                     ADLKLAKAKEFMTEAHRAQTNIIQGEASGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(59238..60485)
                     /locus_tag="KRQ43_000400"
     CDS             complement(59238..60485)
                     /locus_tag="KRQ43_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2740774.1"
                     /translation="MGRLFMNKFIDLLSEKFTPVVNKITKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVALVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDSMLPIAVIMFIGWGLIYGLNFDMFEIIVRIFKPVSDIAQTLPGFV
                     LLNFLVVFLYSLGISGWVLSPITYAIQLSAIAANAAAVASGGLATNIYTYEVVQTGWI
                     TLGGWGATLPLVLMMCLSRAGRIKAIGRACIVPSIMNINEPVMFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYLPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEELKLESQEA"
     gene            complement(60493..60810)
                     /locus_tag="KRQ43_000401"
     CDS             complement(60493..60810)
                     /locus_tag="KRQ43_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2740775.1"
                     /translation="MKNIKVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLPEIDCLLLGPHLDYMKDEIQKKADEYNVPVACISKTAYGRLDGVKALEEALELI
                     LNK"
     gene            61058..62971
                     /locus_tag="KRQ43_000402"
     CDS             61058..62971
                     /locus_tag="KRQ43_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2740776.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     STGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNLTLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDEHFVKLTKKIIKNVYDLYFIDLSDDEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQILENIEIDEDEISYISLHVGSFFDRQKLLED
                     KILCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIS
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYKNKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(63094..64248)
                     /locus_tag="KRQ43_000403"
     CDS             complement(63094..64248)
                     /locus_tag="KRQ43_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBH2740777.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(64530..67145)
                     /gene="mngB"
                     /locus_tag="KRQ43_000404"
     CDS             complement(64530..67145)
                     /gene="mngB"
                     /locus_tag="KRQ43_000404"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH2740778.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNKDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YNRNEIVNAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKISDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIINVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGKKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKIPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKEEALVVRFYNSKEETKSANVVFNKNIKTAKWTNLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(67289..69214)
                     /gene="mngA"
                     /locus_tag="KRQ43_000405"
     CDS             complement(67289..69214)
                     /gene="mngA"
                     /locus_tag="KRQ43_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBH2740779.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDSNNKVELI
                     FLIAVPESEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIVLAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKKADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVIGKPVAA
                     LNNGLINWLNGMTGINAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIHVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            complement(69344..70069)
                     /locus_tag="KRQ43_000406"
     CDS             complement(69344..70069)
                     /locus_tag="KRQ43_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH2740780.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(70332..71111)
                     /locus_tag="KRQ43_000407"
     CDS             complement(70332..71111)
                     /locus_tag="KRQ43_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HBH2740781.1"
                     /translation="MHKMKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPF
                     SRQAIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGK
                     EVFNYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPY
                     YLDSCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSS
                     LIQERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(71104..72531)
                     /locus_tag="KRQ43_000408"
     CDS             complement(71104..72531)
                     /locus_tag="KRQ43_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH2740782.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAVSAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGHEVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            72922..73644
                     /locus_tag="KRQ43_000409"
     CDS             72922..73644
                     /locus_tag="KRQ43_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2740783.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECIGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            73841..75508
                     /locus_tag="KRQ43_000410"
     CDS             73841..75508
                     /locus_tag="KRQ43_000410"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBH2740784.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNLENEKVREECYKVLEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(75604..76923)
                     /locus_tag="KRQ43_000411"
     CDS             complement(75604..76923)
                     /locus_tag="KRQ43_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH2740785.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLIKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYADKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(76964..77710)
                     /locus_tag="KRQ43_000412"
     CDS             complement(76964..77710)
                     /locus_tag="KRQ43_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH2740786.1"
                     /translation="MKKLVKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(77954..79963)
                     /locus_tag="KRQ43_000413"
     CDS             complement(77954..79963)
                     /locus_tag="KRQ43_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2740787.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEEIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQSFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQGVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYSITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(80401..81834)
                     /locus_tag="KRQ43_000414"
     CDS             complement(80401..81834)
                     /locus_tag="KRQ43_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH2740788.1"
                     /translation="MVLRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSREVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMTKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(81921..83837)
                     /locus_tag="KRQ43_000415"
     CDS             complement(81921..83837)
                     /locus_tag="KRQ43_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH2740789.1"
                     /translation="MRRYEQLSKEIIENVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASIGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVIIIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGVLTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTSVVAAMYFKLKDKKIKELCIPAVISGICGVIEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDSIVEISKDNNGQGVVEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTIMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKHFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIIENTQ
                     KHVNNSQELITVLA"
     gene            complement(83911..84771)
                     /locus_tag="KRQ43_000416"
     CDS             complement(83911..84771)
                     /locus_tag="KRQ43_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH2740790.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKCIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(85122..86309)
                     /locus_tag="KRQ43_000417"
     CDS             complement(85122..86309)
                     /locus_tag="KRQ43_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH2740791.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGDNKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIESGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(86323..87714)
                     /locus_tag="KRQ43_000418"
     CDS             complement(86323..87714)
                     /locus_tag="KRQ43_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBH2740792.1"
                     /translation="MSSLKKKKFTMPQTLTIIFSLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMVFLTIGLYLGF"
     gene            complement(88309..90009)
                     /locus_tag="KRQ43_000419"
     CDS             complement(88309..90009)
                     /locus_tag="KRQ43_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH2740793.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLASNGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(89981..91384)
                     /locus_tag="KRQ43_000420"
     CDS             complement(89981..91384)
                     /locus_tag="KRQ43_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH2740794.1"
                     /translation="MIVNKELIIDYLKSNQENIIKDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGENGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTDDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSSAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(91648..92139)
                     /locus_tag="KRQ43_000421"
     CDS             complement(91648..92139)
                     /locus_tag="KRQ43_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH2740795.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPNEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(92165..92977)
                     /locus_tag="KRQ43_000422"
     CDS             complement(92165..92977)
                     /locus_tag="KRQ43_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH2740796.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLMGYEYKKVLSKEAIKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(92990..94141)
                     /locus_tag="KRQ43_000423"
     CDS             complement(92990..94141)
                     /locus_tag="KRQ43_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH2740797.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            94411..95052
                     /locus_tag="KRQ43_000424"
     CDS             94411..95052
                     /locus_tag="KRQ43_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBH2740798.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CTNLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTVDGANTFERDWSKVNK"
     gene            95078..96622
                     /locus_tag="KRQ43_000425"
     CDS             95078..96622
                     /locus_tag="KRQ43_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH2740799.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AVFELATVNKSYTELKEILFSNSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(96839..97465)
                     /locus_tag="KRQ43_000426"
     CDS             complement(96839..97465)
                     /locus_tag="KRQ43_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH2740800.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(97600..98316)
                     /locus_tag="KRQ43_000427"
     CDS             complement(97600..98316)
                     /locus_tag="KRQ43_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HBH2740801.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            98731..99945
                     /locus_tag="KRQ43_000428"
     CDS             98731..99945
                     /locus_tag="KRQ43_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH2740802.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            100564..>100791
                     /locus_tag="KRQ43_000429"
     CDS             100564..>100791
                     /locus_tag="KRQ43_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740803.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPL"
BASE COUNT        32973 a        17812 c        10750 g        39256 t
ORIGIN      
        1 tttaggtatg ctttactata taaaaatgat tttttatctt aattttctaa atataagtga
       61 atgctatcat tttaagtatc ttataagcaa tgtaactata tatctctaat aactactttt
      121 ttaacatgct taaactattt ataagctatt atatttatgt attaacctaa taactttttc
      181 actaaaaaat aacaatctat tcaaagataa actatagtac ttcttctact ttgtttcaat
      241 aaaatactaa ataaatttcg tacatccaca atttttcagg ctacactata aatatacaat
      301 atttatctta gttataagtt taagaatatt tttagtctta ttttgtcgaa tatattttta
      361 ataaaacttc ataattctaa gcatattttt acactgtgtt ttcatgtaca aaaataatgc
      421 ttacaaataa acaacataaa taaaacttaa ataagatgga ttctattcaa catagtatcc
      481 atcttattca ttcaaaacct aaaaggattt tttataatat tatatatttt aaaatctaag
      541 taactcatta tagtatcaat ttcacttaaa gcttacaata cacttattaa tcttgcttta
      601 tattaaaaac atctacaata acaatttaaa tctttaagtg atatccatct cacacctaaa
      661 ggagtgggct ctccgcacta ttctgtaatt cttcaataca atcattctta attttttata
      721 taatttaatt atatatttta ttttaccaaa accagcatac ataaataata cttaaaatag
      781 attaaataaa ggatactaaa acactttatt gaggtatatg acttgaaata tatgaactaa
      841 cttcattagg agaaatatct aaaatagttg caaattcttc acttaataac ctttctgctt
      901 ctttcattat attatcatct gcttgatgtg tttttttacc aatagatttt acatactctc
      961 tgttattatc tatacttctt actaatttta ttaactcttc acatttacca cctctgagta
     1021 tttttttaaa ttgctcactt cttaattttt cattatctat ccatgatgta tccatattag
     1081 gaatatcatt tattaatgaa agcacattaa ttttagaaag taactttctc attggtactt
     1141 tttcattatc tacaggaatt tttattactg tattattaga ataaatagga ctcaatacat
     1201 aatactcttt ttttattcca tttgtaaatc gttcatttgt tatatccatg actttgcaga
     1261 ctcctgtcat accatacatt atataatcat caatcttaaa caaaaacatc accatcctta
     1321 ataaaaaaaa tagttttgac aactaaatcc atcttgccaa aactatctgc tatatattat
     1381 attttaacac attttaagac ttaaatgtaa gtaaaactta tattattaaa attaaaaaat
     1441 acattaacca ttgattaatg tattttttag atttttataa caagcatatc aaaataaatt
     1501 aatacagctt atctcctgtg aatacctata aaattggtgc ttggctattc attgagtacc
     1561 catcatttct tacatcattt atttctaata tttcatcatt tgttttaacc ttagtaagtt
     1621 ttttaactgc tccataaggt tcttttaatg aaattttatc tcctcttcca gaaataaccc
     1681 ataaaatttt ataccctcta ggtattactt gtagtttatt ttcaccttta ccatcagtaa
     1741 agtagactaa caaattaatc tttttattat tagcatactc aaagactgga gaaaatctag
     1801 tacctccacc tatcctaatt ctatctttta tatctttttc agttctcact ttatatacac
     1861 gtctaatttc attatcacat tctataattg taatttcatg attatagttt ttcactatac
     1921 taagaacttc tttaatagct tgtttaaatt cttcatcact aatacttcca cttacatcaa
     1981 gtgcaactgc tatttctgcc ttatgacttc taagttctcc cctcaaatct aaacgatttg
     2041 gttgtcttct atttcttctt gttatagtct tctttttatt attttcaact gttcccatta
     2101 ttctattaag atataaattc catggcaatt cacccttact atttttaagt gatgatatca
     2161 tactttctaa ataagcagga actttacctt tttgagaact gttaataaat ttttcagtaa
     2221 attctctaag ggtattttta tctatctcat tggattcatc ccatatatca tgagttcttt
     2281 cggggctata atcaatttct acatctccat atttatcact atcatcttcc tcaccatctt
     2341 catccacttc catcaaatct aattcagtct gaatcttttc tacataatat tcaaaaggtt
     2401 catatggttc aagttttaag gaatatttta aatttaccca ctctaaggta gttgcatatg
     2461 gtggtaaatt gtttagaaat ttatttacta ctatatccat tgccatatta attgccaatg
     2521 tactatactt tccttttaac tcctttgctc tcatcaaatg catagataat atatgatgaa
     2581 tttcatgttt aattgtagtc tccatttgct ttatgtcaag cgttaaaaag attattggat
     2641 taaaatatat aacatattta gctcccttaa aattcacgcc tgtaggacta cttatatcaa
     2701 atcttatttc tcttgacatc tgaaacaaaa aatatccata aaaattatct tcttcttcca
     2761 taagacttaa attcacttta tctacaagac taaaaaactc atacttaaaa tcttgtggta
     2821 tatccatatc aaatttctca ttagcacgat ttgcctttag catagaatga gtatttataa
     2881 tttcacttgc tttattataa agctcttttg cttgtttatc aaaataattt tccatacatt
     2941 atccccttat taagctataa gattcaaaat atgattttac aaaaccttca ttttctatgg
     3001 cttttttata tacttcaata taactgtttc taatatcctt cataatacct atcattaaat
     3061 ctacaggata catttttaaa aattcaataa atctattaat atagtggttt gattcatatt
     3121 tatcattctt aatatttaat tctaagtctt ttagaatgtt catagctgat agataaagtc
     3181 ttgtatgact ctcatttttt actctttcta caatgggctc atcaatagat tctcttaaaa
     3241 aaacatcttc ataggatatt aatggttcag agtttgattc aataaaactt ataaattctt
     3301 ctgcaataac tttacctaca ttacccttta caacatttaa aaatactgct ctaggaatag
     3361 aattattttt ttctttataa actttataaa ttttagatac tctctcataa cttctaggag
     3421 tagctcttac atcatcttca tttattttat gcagatattc tggaaaagtg gaaataaact
     3481 cgataacttt tctttcaata ccctcatcta ttgcccattt tatccattgt gtatggtcac
     3541 tctccatatt taaccaaaca aacctatttt cttgggctgc atccatatct accacttgat
     3601 aatcaaaatc tgaaccatat ttacttgatg gattcattgc tgctaaaatc tttacatcat
     3661 catgcagttt atatccatta atttctctat ttaaaattaa attcataagt tcttgctgta
     3721 ctgtatgctc acaacgattt atctcatcta taaataaaag aactgtctta cttttagata
     3781 tctcttcatc aatttctctt aatttgttat gaacagcata cactgttgtt ttcttttcag
     3841 tcttatatcc attagaatta actcctacat aagattctat agttggaaga ccacctattt
     3901 caccctcttt aagtaagttt ccatcaataa caattaaact ccaatcattt tctttggcaa
     3961 gcttatttgc taaagctgtt tttcctattc cactttcacc tactattaaa ggtacttctc
     4021 cagtggataa tattaagtca acgcttttta atgtgtctat aaaattcatt tttctctctc
     4081 ctacataatc tttaatttct catctacagc tatttttttt gctgtcttac ttccatattt
     4141 ataaataaac ataattttat ctattggtat actttcgcta tttctatcta taacactaca
     4201 attcaaaaaa tctctaatat acttttcctc aacatcttct ttggataata cttcttttaa
     4261 tacactctct aattcatctt tagatacttt tttcagaatg tacttaatca ctaaaatatt
     4321 cacttttaaa aattccaaca ttttattttt atctaaatca gttataaagc taatagctgc
     4381 ttcattattt tttatagcta taagttctgc attataacta ggtgaatcta tatatctcaa
     4441 ggcatcataa cttattctta ctgcctcctc ttgtacactt tcataaggtt gttttataaa
     4501 ctttatcgaa tcataatttt ttcttactgc taacagttgt aattcttcac ttggattttt
     4561 agcatattta attgcccatc ctgcttgatt tatagccatt tcaataactt tatcagttgg
     4621 gtttttgata taatccagta tactccatcc ctcatttact gcttttatca tcatatcttc
     4681 tgttggatta tctataaatt taattgctct aatattatta tctattgcta gttcttgcat
     4741 ctctctggtt ggattattta tatattctag tacaagccca ttttctttaa tagctaacaa
     4801 tttcatttca tcagttggat tatctattgt agctataata ttgggattat tttttatcat
     4861 ttcaataact ctcaattttt ccataatgtg cctttctttc tataattatt tttatatcta
     4921 tattaattat aataatctat tcctatttat ataattgttt cttattataa ttaatatact
     4981 ttttaatcaa atttaaacag aataattata ccaatatata aaaaaatttc taaaaaacaa
     5041 taaaattaag ttataaacac caatatattt ctattatttc aataagtata caattagatt
     5101 agaatctaac gctagtaata aaaaattact ttcccaaaat agatataagc ctcattttat
     5161 cgttcaaata atgaaaatat atttgatttc atgcaaaaag agtgcctaat gaactaaaaa
     5221 gttcattttg agacactcat ttctttatat aaatttatat agtttttaat cgttcgcatt
     5281 caaccactca gttaagactt ttatatattt ctcattttct tcaacgaatg gcatatgtct
     5341 tgaatactca aataactccc acttactatt aggtattcta tcatacatag tctttgcaat
     5401 atatggcgaa cataaatcta ttgctccact agttactaga caaggctctt ttatttcatg
     5461 taatctatct gtaaattcat atccagaaag agttcctgta ggagaaaatt cattttgtcc
     5521 ccatcctaca atatatgctt cagaacctga ttttttaggt cttctcaggc actctggaga
     5581 atcttctgtc acttcacctg cacaatacat ttccataaat ctttctaatg catcattata
     5641 ttctttatta gagtaatctc cagtatttac tgcatcaagc aatgcttttt ggtcaacctc
     5701 actcatatat gatattcttc ttttttgttc tttctcccaa agttttgcag aagaaagagt
     5761 agatgaaagg atgtaagact taataccttt tggtttatat tcaatagcat accaaatagc
     5821 ctgcatacct ccccaagatt gacctaacag atgaatttca tcaagtccta gatgttttct
     5881 tagttcaata agctcctcta tccaagtatc tgcattaaat aactcaggat gcccttctac
     5941 aaaggaattt ccacaaccaa tttggtcata cattattact tgtctaccac tttcagctat
     6001 cttatccaat acctcaaaat agttgtgtgt agaacctgga cctccatgaa gtaatactaa
     6061 tggcttcttc ccttccgtat tttctcctac tatacggtaa tacgttttaa aacctttaaa
     6121 aggcatatat ccttcagtaa ttttcatatt tatctcctcc aatttgtaat tataaacaat
     6181 aatcaagttc attaacaata ctatttaaaa cctctcatac gtatttaatt atgtctttta
     6241 atctttatac ctacttttat aaatagtata acataaaagt taaaaatctc tatactaaac
     6301 caattataaa attatattaa ctatataatt ttatttttta ataatagtat atacatattt
     6361 gattattttc atttgctatt taaaatcaat tttaagtttt cttcttataa taaacttcct
     6421 ctttgtggtc tcatgttagt ctctaaattt aaaattttac aaaaaatttt cataaaataa
     6481 aattatattg attgtatcta aacaaatagg gcaataaaat aattaagtat agttacttac
     6541 ctttcaagca atattagttt tatgttagaa ttttattata ttgatttaca ggaggtttgc
     6601 atttgaataa tattaattca cttaaagtaa taaaattatc tcttggatgt tctcttgcta
     6661 tattcattgc ttggctatta aaattagaat attcaatggt tgctggagtt atagtactac
     6721 ttacagtaaa ggacactaaa agagaaactc ttaaaggctc cattggaaag atttatggtt
     6781 ttcttttatg tactattttt tcatatttat gttttaatat tttaggatat aatttgactt
     6841 cattttcaat atttatattt ataattatac cactttgttt tttgttaaat attcaagatg
     6901 ttattgctat gtgtgtagtc atagcatccc attactacct tcaaggagaa acttctatca
     6961 aatggatttt aaatgaagct ggaatatttg cagtaggaac tggaataggt gtcttaataa
     7021 atatgtatat tccaacaaat atacataaaa tccatgaagt tcaaaaaaag ttacaggaag
     7081 aagtgagtat tgtacttata gacattgcag atattattgt aaatcctaaa aaagaaaatg
     7141 gatatagtag agatttatat aaattaaatt cacttattga cagcagtatt tctgaaactt
     7201 acgataatat taataatact ttattaagtg atactagatt cttcttagaa catatggata
     7261 ttataaaaag ccaacgggat atcttagaaa atttgtatag ttatgtatct caactaaatt
     7321 ctacaccacc acaagctcac attctatctg ctttcataca taaaataggt tatactgaat
     7381 ttgaagctga aacaggcaat cttcttcttg aagaattgaa gagattaatg cttagtatga
     7441 aaaaccatcc tctacctgtt gacagaacag agtttgaaaa cagagctatt ttattcctat
     7501 gcttgactga gttaaaacaa tttttagtta atcgtaaaca tgctcagatg cttagagata
     7561 ataattttta taaataaaaa ggtgagaaat ccagcagttg acctgactac aaaatatcag
     7621 atataatatt aaatgcgccc ctagtaagag ggcgcgatgt ttataactta ttctactgtc
     7681 atgattaaat cattattcat atcgaatata cattatttga ccaagtccaa tattagcttt
     7741 ttcatcagtg atttctattt taatagtcac atcatttttt ttacagtact ttgctaattc
     7801 tgcaccagaa cgatttttac cactaaaatc taaagaaaat ggcttatcat atttaaaagg
     7861 atattcaaca ggttcacctt ctggtgctaa tgcaaacatc ccatatggtg tgttcataaa
     7921 tcctattaca gcaattgtaa gatttgatgg gtctaaattt gatttactac ctagaaatgt
     7981 aactgtattc actgatgaat taattacaac acatctaaca ccttcataca ttacatgttt
     8041 atcctttata tctccaaatt ttccaacaac ctttgccccg tcttgatgtg gtaacatagt
     8101 gtgcttccca ggtagtgctg gtttttgcgt ttgtgctact gctccaactg ttggatatgc
     8161 tgtcttatca aatggtaatg ggtggctaag actcttgtat atgatatcct ttcctgctga
     8221 tttattagca tcaatatcta catgatacaa acgcccatca ccaaaacgta taagattcca
     8281 ctggtggtca tttgatgtgc tgtgtacata ataagattca attcccatag cgtcacacaa
     8341 agctttcatg ctcctagcca ttcctgaaca tgcacctttt ttagtaacca atgtataggc
     8401 agtattcgct ccttctactg cattccagtc aacatatgtt gtgttatttt taatgtgatt
     8461 ataggcaact aaaatcttag cgtctgtagt catgttcttt gtaattttat tgttcataaa
     8521 atctgctgtt gcttgtgcta ctgagtttag ttgggcttgt gacagctttg gaccatatac
     8581 gctattggtt ccagtgacat agctttttgg tgtttttgct gttacctctt tggctgtcat
     8641 accataaact gtcatactca tacctgagac taaaacaatt gttgtaatca ataacttggt
     8701 agctaacttc ctaattttct tcatacttag tattctcctt tataaaatat tgttacttcc
     8761 tattctctac cattaataaa gttcatttgg gatttaaaaa ggtggattgt caatatgtat
     8821 gtttcttcat ttatacgttc gtgaaatatt taaatttcat ggaaaatcta atagatattt
     8881 tctagataat ttgtatacaa tacaactcgc aaatcagggt gtttgctgtt agtttgagaa
     8941 aatgatgatg attaatatat tcggaatctt tgacctataa taaataccat tgtcttcaat
     9001 cattaataat ggtaagagta aagagaatta tcaataatac agttaaaatc aactttgtat
     9061 acatttcata cattctctcc caacaacatt atacttctta taatttgtat attcaatacg
     9121 ttttctggga aaatatagga tatatctata aaaatataaa aaaggagttg aacttaaaat
     9181 ttgattaaaa aaaatcaatt ttaagacaac tcatttgtat tataaaaatg ctatatatta
     9241 ttattaagta agtcaatatt ttagatattt atctatttct tattgactta cgcttatagt
     9301 ctaacttatt tgtttagttg atatataacc tagttttaag cattattaat atttaaataa
     9361 tcaagtatcc tttttgtttc ttgtagtttc tgttctgcct catttaagtt ttcttgaatt
     9421 atagaaatat atattatatc tatcaacgta agcattgcta ttcttgaaga aatagctcct
     9481 tctctaagcc ttttttctat atttggtact actagcttta aatcactaat cttactaaga
     9541 tgattgtcac tatatttagt tatacaaatg accttacatc cttttaattt tgcattttct
     9601 atagacttta ttacttcttt tgattctcca gagtaagata ttgctatagc tatatcttct
     9661 ttatctacat ttgaagatac cataagttgt gtatgactat ctaaagaggt aaatgcctgt
     9721 ttatttatcc ttaaaagttt catctgtaaa tctagtgcaa ctaaagccga accacctact
     9781 ccaaatatat atacattttt agcctttatt atctgttcaa ctgcttcttt tattatatct
     9841 ttttcattca acaaccttgt ttggttgata gtctctatgt ttttgtttgt aattttgttt
     9901 ataacactat ctatattaca atcatagttt tcatctacat atgtgtattc attttctttg
     9961 cccatcaaat ctttagctat ctcaattttt aaatccccaa aacccgaata tcccattttt
    10021 ctagaaaacc taactatact tgctgtactt gtttttgagt ttgacgccaa ttctgataca
    10081 gaaagcttac ttatagcctc tgtattatta agtatgtaat cagctatttt tttatctact
    10141 tccgttaaat cttcaaatat ctgttttaat tttaaaatgc aactcatact ctaccacctc
    10201 tacctattta ctataatatt tcttcttagc aagtaaacat gctcctaaat ctggagtcaa
    10261 cactggtctc actataccaa atctcgtttt attcaaatat tttttaagtg gctctaatat
    10321 taaatctcct gacttaaaca ctccacctga ataagatacc tttatctttg taccttgttc
    10381 aaaatgatgc tctaatccta ttataagcct acttaattca taagctgcat catcaaatat
    10441 tttactagca gtattatcac cttcaataac tgcttttaaa catatcgtag caaactttgc
    10501 tatttctatt ctatctcctt gtattccatc atttacatat tttattatgt cataatcatt
    10561 ctctatatta agatgtcttt ttattaaatc atataatttt gtctttgaac accttccatc
    10621 agactgcatt gtgaacattt ttaaggtagc cattcctata taatacgctg aaccttcatc
    10681 tcctaataca tagccccatc ctccacatct gtgaagattc ccatctttat ctaaagcctg
    10741 tgctattgaa ccagtacctg caattatatt tatacctttt tccccattta aagaacctgc
    10801 taatgctatt tctacatcat tacctagagt ataatttata tgactatatg cattttttgt
    10861 tgctacttct aatgcataca atacttcttt tatttttcca tatccagcaa gtccaacaaa
    10921 tgcatacgtt atttcttcta catttatctt agcatcttta caaacttctt ccaacccagt
    10981 tattaataat ttcgttagat tatcaaatcc tatttgatta taatgacaag ttcctttggt
    11041 tatggttcct actatattta attcttcatc tactaatgta aatgttgttt tcgttcctcc
    11101 accatctaca cctaaaaaat acatactatc ctcctacaat atctttaata attctttcaa
    11161 tacttaatat ctaaaaataa ccttccaatg ctgttttttt aatattgaaa ggttatcagt
    11221 actattattt attttacaat ttttctattg attttaaagc ttcacttata taaccttctt
    11281 gtctatctag gatactcttt gcactatcct tatctaaacc actttttatc ataaatatag
    11341 ccaatttaac tctattatct gcttcttcta agaatttttc tgcaacgtca tattttacat
    11401 ttgtagctat cattattatt ctttttgctc tttcaaccaa cttttcattt gatgtcttaa
    11461 catctaccat caagtttgag tatacttttc ccatcttaac catagaagct gttgttaaca
    11521 tattacatac cattttttga gctgtaccac ttttcattct agttgaaccc attattactt
    11581 ctgcccctac tataatgttt attggtaaat ccgctttttt actcatttca ctattcggat
    11641 tcatagttat tgatagtact gcacacccca attccttagc atactccatt gcacctataa
    11701 cataaggagt ccttcctgat gcagctatac cacatataac atccttagat gtaactcctc
    11761 tatctattat atcttgcttt ccaagttctt tatcatcttc agcaccttct attgctttaa
    11821 atattgcttg atttccacca gctattatag cttgaacaag ctcaaaatcc actccgtaag
    11881 ttggaggaca ttctgtggca tctagtattc ctatcctccc actggtacct gctcctatat
    11941 agaataatct acctccctgc ttcattctat ctactattat attaacagct tttgctatac
    12001 tctccttttg ttcttcaaca gcataggcta cagttttatc ttcgttattt attaattcta
    12061 ttatgcctaa tgtatcttct ttatctattt gcaatgtatt cttatttcta ccttctgtaa
    12121 ctaaattttc taaagttttt attaacatat catttcctca ttttcttaat attaaatttt
    12181 taaacacatt ttaactccaa ctttcataat tatattttta taataaatta atattttcat
    12241 aataaattat tttgttgagg gtttaaaatc aaacttttgc catggtttaa tataatctaa
    12301 tataaataat tcttcttttc ttatatatcc tactacattc gatttaccac tgtttttcat
    12361 atcagtcaag gctatttgta actcccctgc ataatgacca tattcactac tttcaattac
    12421 tatatctcct ctttttatta ttttaggagt attaaatagt tcaaatttgt atcctttata
    12481 tttaacacga gattgagtag accttatcag actgtcagat atatcccctc tattaaaatg
    12541 tatttcttca aagagtatct tcttctcaac ttctcgtata ttttcctcta ttgctacatc
    12601 aaatgtaacc atatcttttc tcatagaacc taataccttt agctcctcat atgttggata
    12661 acaatttgat attattatat catttatatt attcatagct attatatgct ttacttgaat
    12721 atctataggt agatttctgt gcatctcaat tgttggaagc ccatcagtta caggccatgg
    12781 tccaaatgtg gtttcatttt gacttgttac aaaaactgct gttcttaatc catacttatt
    12841 aaatctttct gtacatttta taaagtgttc taaatttaat ccactatatc tatgtggata
    12901 aaagttatga catcctgtca aattttcttt atttggttgg tagtccatta ttgtatctat
    12961 ataattagta ttattactca tattgatttc tattttaaga ttttgaggat taaaagtcat
    13021 taaggccttt tcagaacctg taaatcccat atcaagcctt attccgtctg ccttcgtctt
    13081 tttaaaaaaa gtcaaatctt tgtagcttat ttctaattca ccaaatactc tgggatttac
    13141 atcaagtatt acctcaaaac ctttaaactt agcgtattca tttatacttt taaatttttt
    13201 aattatattt tctttagtat ctttaactga taataaacat gaaaatatac gtgtaaatcc
    13261 attttcagca gctttatcta tataatcata tatttcctta gatgttgttt tttctggata
    13321 aattgatatt cctaatcttc ccatctgtgt catctcctta tatcctatat gtgtttaaat
    13381 ttatttcgaa ttacacgaaa cttttttaaa aatttggtga aaaaaagttt catatatatt
    13441 tataaaaaaa gaaaagttta ccttttcttt ttttataaac aatcaacaaa atatcttcgt
    13501 tacttatttc ataactgtta tactttgaaa tttatactaa tctaatatag tttttaattt
    13561 ccaatatagt ttctaattaa taagcttctt gctcttcaac tttttcttca tgaagcaatc
    13621 tcttatcgta catcttgaca aatggatagt aaattattat tgatatagct atacataata
    13681 agttaagaac tgaagctctc caatctccac cagtggctaa atatgcccct actggtcctg
    13741 gtaatgtcca aggagcagta actactactc tggatactaa attagcactc atagcaaacc
    13801 atgaaactgt tgccattact attggtgcca caacaaatgg tattattaat attgggttta
    13861 atactattgg tgctccaaat attattggtt catttatatt gaatattgct ggtattacag
    13921 ttgcttttcc taaagacttt ccataagctg attttgctct aaatgcaaga agtaaagcta
    13981 agcctattgt agctccagaa cctccaatcc atataaacca ttgaaaaaag ggttcagcag
    14041 caatacctgg aactgcttga cccgcagcat atgaagctgt attagcatct aataattgta
    14101 tccataaagg tcttgccaat gaacctatta ttgatacacc atgtattcca aatgaccaaa
    14161 aaaacgttat taaaaatatt agtataatta ctgatggtaa tgtgtcagtg gctgaaacta
    14221 atggagttac taatttagct atgaagccat gccaatcaaa ccctaggaaa taagtaacaa
    14281 tagccattaa aattattatt aatgcggctg gtgtcagagc ttcaaaagac cttgtgactg
    14341 atgctggaac tgcttctggc atggttatct tgaatttaga tttgtcagta aatctataaa
    14401 tctcaacacc tattatagat gttacaatag caacaaacat tgaacctcca ccaagattag
    14461 ccattggcat ttgccatcct tgaggaattg aattatacca agctaaaagt tctggactct
    14521 tttcaactat ctttaataaa tcaggggtaa gaccctctat tgcagtagga actattgtca
    14581 aaaggaatgt agctgtagct aataaacctc ctgtcaatcc atctaactta tatgactttg
    14641 ccaaactata acctatgcca aatgtagaat atactgatat aataaaaaat gtcattctat
    14701 atggtagtaa tattgtaact gcattttcct ttagatactg agttaccccc catgaatctg
    14761 gtaatggagg aaatgctaat atcaagaaaa atgacccaac tattataagt ggtaatgaag
    14821 ctacgattcc atctcttaca gctcttaagt gacgttgttc tgccaatctg gccatagaag
    14881 ttgataattt actgtctaaa aattctgtaa atttatctag catcttttct ctccttaatt
    14941 aatatttatt tttattatca ttaaaatttt tataaaatta actttcttct aacctaacaa
    15001 cactgcaact actatttact caacaactct tgaacttgtt ttaataactt tggtcctcct
    15061 aatggactat aagcttgtgc ttgtattaat gcacatggta cactagcctc atcagcaaaa
    15121 gcttttaaat agtcaaatct atgtctgact tgtggagcta ccatagcaat atcccatcca
    15181 tttttaactt cattctcaaa ctcttgagta ccaacagcca aaacatctat atctattcca
    15241 ttttttgctc cttctttttg taatgcatta actgctatag cacttgacat ccctgatgaa
    15301 caaacaaata atactctcat attgattccc cctgtttttt tatttctttt caatcattat
    15361 agcatgtatt tttgattaca ggaatacgtt tgtatatatt ttttcatatt ttacattttt
    15421 aattgtaatt ttatttcatg catttatatc ttgctttaat tgctttattt atctaatcat
    15481 tcttttgtct aaaattacac actacttaaa atactcatat cttttcttaa aaaagaaaaa
    15541 agactatctt ttattaacat aaaatagtct caatactttt ttaaatatgt attcctttat
    15601 atatccagaa gtaacctatt attgcaaatg ataaaacaaa taaaatatac agtctaaaaa
    15661 atcccaaaga aaaacctctc ttagtttcaa caaagtatct tgtatatgca actgcaaaag
    15721 atgtaattaa tgaatttcct ataacaactc caaatctatt atctattcca aatatagata
    15781 ataacaaagg aaaaactaca gtacttacta gagatgaaac tattagtatt aatccacttt
    15841 taaaacttat agttggaata ttataatctg ttctttgatt tttctccatt tctttcttag
    15901 tatttttatt actttttgca tttttataat tattattttt ctttcttttc ttttttttat
    15961 tattagacat gtcatttacc tccaaaaggt ttaggtgtta tattccctaa aataacttta
    16021 tttttagccc ctgttgcaga tattacatta gaaaaagaat tatttaatgt ttcattgccc
    16081 aagattacaa atgccaaagc ctcctttgca tcagaagaat acccatattc atcttgagtt
    16141 aatacttcaa cctctaataa taactctttt atatatccta ttaaagttag attatgaact
    16201 cctccacctc caattaataa agtatctaca ttaacctttg gaagtatgaa gtttttataa
    16261 ttataatata tagcttttgc cgtaaacata gttactgttg ctatcaaatc atatttatct
    16321 acatgtttat atttgttaag catgttatcc aaatagactt gtccaaatac ctctcttcca
    16381 gtgcttttag gtggcgcttg actaagatac ttatgactca tcaaatcttt taacatttct
    16441 tcattaattt taccttttga tgcaaagtat ccatttttat catactttct attaaataat
    16501 ctttgacata ctccatctat tatcatattt cctggtcctg tatcaaatgc aaatacatca
    16561 tctatgttac atgatttagg tattatagta atatttccta ttccaccaat attttgaagt
    16621 gctaaatttt tatttttatc actatataat aaaaattcac tatatggtac taatggagca
    16681 ccttctccac ctgctgctat atccattact ctaaaattag atattacctt tgtatttgtt
    16741 tcatatgcta taattgctgg ttcacctatt tgaagcgttg aagatacaaa attattataa
    16801 cttcttggta tatgaaagat tgtttgacca tgagatgcga taaaatccaa atttgctata
    16861 tgaaagtttg ctttatgaca cactgatttt acagctttac taaataaata tccaagctta
    16921 aaatttaagc tacagattaa atcaacactc gattcctctt ctatacagca ctttcttatt
    16981 tcgtctttta tatctttagg aatttctaga gttataaatt ctatttgctt aactttagta
    17041 tttctaccat tcccactaat ttcagctagt actgcatcaa ctccatctaa ggaagttcct
    17101 gacattaaac ctacactata catagttatc atccttttaa gtttatagtt attcctcccc
    17161 aaatcaaggt attaagttta ataattttag aattaatctt atttcatctt taattgcgat
    17221 aatttactct tacgaaatta atcgagttaa tcttatacac gttttttacc ttagctaaat
    17281 cttacattaa tttattttca gtgtcaatgt aatgcatgta attttttttc acaaacaaaa
    17341 catattctct ctccaaaaac catattaaaa tagttactac aaataaaaaa cataccaggt
    17401 acctatctga tatgtttttc atatataata attattattt tataatatag atagaacatc
    17461 atttaaggca ctaattaaat cttcactatt ttcaagaact aaatttattc ttattgtata
    17521 tgtcgatttg tatatgatga tagattttat agtctaataa cctaactatc taggcttaaa
    17581 taatccgata tatcataaaa gtagatatta aaaattgtat atgaaccaat tttcgaacat
    17641 acctcaatct catgccctaa actatctatc attttcttta caaaatacat ccccattcca
    17701 gtagacttat acaattgatt tcttccattt ttccccgtaa atcccttgtc aaaaacccta
    17761 gatatatctt cctcatttat acctatacca aaatctttta tagataatac cactccattt
    17821 tctaactttt ttgaattaaa ttcaatctta ccaacttcct ttgaatactt tatagcatta
    17881 ttaataattt ggtctaaaac atatgacatg catttagaat ctgtgtaaac atcattttct
    17941 aattcattca aactaacttc tacattattt tttataagca aaaatgaatt attttttata
    18001 gacattttta ccaatttttc taaattaaat ttatttataa atacatcttc aaacatagtg
    18061 ttgcttctac tactatacaa aatagagttt actaaaaaat ttatctttgc aacctgattc
    18121 ttaatatcca aactatcttc tatgctactt aacctatctg taattatact taaagaagat
    18181 attggaattt ttatttcatg aacccattta gctatgtaat catctaattc ttttaatgat
    18241 tgtttataag tctctatgtc actattattt tttattttta agttttctat aatatctttt
    18301 attagatttt cttcaaaaga ttgtccatca attaaataac tgtctatttc accactattt
    18361 tctatacaat tatataaatt tatataacta tttctaaaat ttatataatc tataacaaaa
    18421 aataccatta ttataaacag cactaaaaaa tctaagtata ttaattctga atatctattt
    18481 tttaaaatat ctatagcaaa taaatagata tttattatac taactacaac taaaggtaga
    18541 gcaatatact tagacctacc ttttaaatat tttactagca ttatattata tatcctatcc
    18601 ccttcttagt ttttataaaa tcatcaaaac ctagttcttt aactttactt ctcaatctat
    18661 tcatatttac agtaagtgca ttgtctgtca caaactcatc attatcccat agagtcatca
    18721 taagactttc ccttgataca accctattct tattttttaa taataatgtt aaaattttta
    18781 tttcgttttt agtcaactct atacttttat ccttatactt atgttttata atccctttcc
    18841 ccacatcaaa catcaaatct tcacaataca aaatactatt agaatcacta taattataga
    18901 ctcttcttat tataccattt attttggtaa ccaatatgtc tatagaaaat ggtttggtaa
    18961 tataatcatc tgctccatta tttataccca ttattaaatc catatcagaa tctcttgatg
    19021 ataaaaatat taatggtaca tttgaaatag ctcttatttt ttcgcaccag taaaatccat
    19081 tatataatgg taaatttaca tctaaaagta ctacatctgg ttttttatcc ataaattcat
    19141 ctaatactac ctcaaaatca tcaattaatt ctactttaaa tccccatttt tcaagtgcta
    19201 acgcaatctc ttttgataaa tcaatatcgt cctctactaa taaaattcta tacatttgta
    19261 tattctccat tatcctaata tttcactatg ccatgaatta ttaatatcat aacatatttt
    19321 atataaattt attacccaaa ttatttagtt aatcaacaag gagactctta ttacaagaat
    19381 ctcctttctc tttattaata tatcaactaa tttttataca ctacactctt aaacttatta
    19441 acagatactg ctccatatat tacgaatatt atcaaacata tcactaaact tagtatatat
    19501 ataccagata aatcgttcat caataaatct cctgctaatc tcaatgcaaa ataactagat
    19561 atagttgcac ttaacattgg caaagtataa aatatagcta cttctttaag tatagctcta
    19621 tttatatctt tttctgtagt acctattttt aataaaatct tgtatttctc tttatcttca
    19681 tatgcatcac tatatatttt catatatatt atacttccag ctacaattgc aaagactaag
    19741 aataaaaaca caagcactac atatgcaaac ttcatccatt gactctcacc ttgagcttta
    19801 tatccattct gaatatatcc attttttaaa cttaaattct tttcaatatt gttgaacatt
    19861 acttggctat tttcttcttg aaataccttt gcaccataaa aatatacttg ttgaccctta
    19921 tctcttagtt taaaatatgt atcatcattt accactataa tactttgatt aagtcctgtc
    19981 cctaatactg gaacttttac ttctcccctt gaaatattat ataactgacc atcaagtttt
    20041 gtcttgactt cttttgtagc tattgatgct atcgtttgag gactttttag ctctattaca
    20101 ttatttccac taactaatct ttcaccatac tcttttaatt ctttatcatt gccattcact
    20161 ttaagagtat tacaaaaatc actatatttc attatagtat ctgttgtatc ataagcttct
    20221 tttatatctg ttttctttaa gattgttagt tctggattta cggagtactt tatcttatta
    20281 gtatctttta ttatgttctc tatttgtttt ttattcactt catctttatc cattgaaact
    20341 atgctaatag tgtacacatt tctttgttct tgggcattct tatgtatatg cttcatagca
    20401 actgaagcac caagagttga tattgttgta gttataatta tagctattat agcataagtt
    20461 ttatagtttt tatttaatcg gtagtttata ttgtttatcg caattatatt atttccatta
    20521 aataatattt ttttattttt gattataata tcaaatataa caggcataac tgatttgaat
    20581 aagccataag tacctactat tattatacct ataacaggta gtacactagt tatatctcca
    20641 gttcttatat tcgtagaaag atagtatcca tatcctatta ctataagtga tactatagct
    20701 aatatatata tacctattcc tacctttggt attttttctt gttttttaga tatattgatt
    20761 agatttatta cactacttct acatattgtt ataaaacctt ttacagccat tattataaat
    20821 atagaaataa agattaaagt agcatatagt atagcttcta tgctaagtcc attagatacc
    20881 tttatattaa atccagataa ttttattatc actacttgaa aaaatctaga tgttattatc
    20941 cctataatta ttcctgttat acaagaactt attcctataa gcatattttc tacaaaatat
    21001 atttttccta tagtatataa atctaatccc ataaaggaca atattccaat ttctttagac
    21061 ctattcttaa aaaatatatt tgttgcatac catataaaga aaaataaaaa tactgatagt
    21121 atcattatta cagctactaa cactgatagt gtaaattttt tattttcctc ttgtaacaca
    21181 tttatagcat ctccatatct taataattca aaattagtca gcacaactac tgaaaaaacc
    21241 atagatataa aaaatgctag ataagttctt atgttactct taaaattatt ataagcaatt
    21301 ccaagtatac tcacttacat ctcacctccc atagaggcta gcatatccat aatttttcca
    21361 taaaattctt ttctactatt tcctttgttt aatttacact ttatatttcc atcatttatc
    21421 atatatactt catttgaata acttgccgtt agagggtcat gtgtaatcat tataatagta
    21481 gcgttgtttt ctctgtttat tttttctaat gattctaaaa gttcatatgc tgatttagag
    21541 tccaaagcac ctgttggttc atcagcaaat atgactgctg gatttgtaat taatgaccta
    21601 gctgctgcgc ctctttgttt ttgtcctcct gataactgat atggatattt atctaaatga
    21661 ttttctaatc caaatttttt agctatagaa aataccttag cttctatctc cttgcttttc
    21721 ttttttccta atgctagagg aagtgctata ttgtccatta gtttcatatt gtctaataga
    21781 ttatagtctt gaaatataaa ccctattttt tctcttctta attttgatag ttcattattt
    21841 tttacttttg atatattaat tccatctagt attatttctc ctgaagtttg tttgtcaagt
    21901 gtagacatta aatttagcaa tgttgtcttt cctgcaccag atggacccat tattgctata
    21961 aaatcacctt cattgactgt aagagatata ttttttaaca catttgtttt aaatcctttt
    22021 attccataat cttttgatat attttttatt tttaatattt ctttcataat aatagcctcc
    22081 agttgctaat tttttaatat atatttattt taaaggtttt atataaataa atccttaagt
    22141 aaatattaca ttttaactgt tagcattaca cttttgtaac atatggaaga ctattataat
    22201 tatagtggaa atatcttaaa ataaaagcat gattcacttt tttgtataaa caaagaaaag
    22261 aagcccctaa gaagcctcta atctatacaa taattcttct ctataaaaaa ccaaaaatac
    22321 aaccttgatt gtggcaaata caggtactat aaacaagtga tattactact atatattaaa
    22381 acaattattc ttgaagataa ttcaataaga ctatcaagcc ataagctaag catccaaaaa
    22441 gacttaatat cattaatgta taattatacc caatattaat actcaaaaaa ccagcaacag
    22501 ttggaataat cagagatgaa cctcccataa atatacttaa agctattaat tggctactac
    22561 ttctaagttt tttaggagaa acttcaaata ttaatctttt tgaagtaatt aaaattaaag
    22621 gagtagaaaa cacttgaaaa acacacagta taataatgat atttgaatca tttgttaaag
    22681 caaataatag aaactgaact gttatcataa tagcacttaa ttttaataag tttaaactgc
    22741 tatatttttt taataaataa gaaccagcca gatatgttgg tatctctaat aatgactgta
    22801 aagaccactt taaagatatc tgagaatttg tagcatttaa agctatcatt ttatctatta
    22861 cagtacagtt atttgctacc accattgagt ataataagaa taaaatacat actagtaaga
    22921 tatatttttt atcttttaat aattcaataa tatctttatt agttacattt attttcttat
    22981 taatcttttc aatatcaggt aataatagta tatttataat aagtaatact acaattaaac
    23041 caatcgctac agataatcca aaatatgaga atctaagaat caagtaagat gctaccatac
    23101 ttccaatagc ccatccaatc gacccaaaag tcttaataaa tgacaaataa ttattaatat
    23161 tatctccaca acctattatc catgtatcat ataaactaca gcaagtattt aataatcctc
    23221 ctgataaagc aacaagtaat aagtatatta taaaagttgc agattcagta gaaaacataa
    23281 taactgatgc aattccataa actgataaac taattaaaac aatttttttc attgtttgat
    23341 acttatcagc taatactcca aataataatt gaaataatat attggttatt gcatagctcg
    23401 ataatataat tcctctttca aacgctgagt aacctaattt tgataagaaa ggtgtgaatt
    23461 ttgttgaagc aaaggcaaaa ataatatatg agaaaaaata gaatatgata aatttaaatt
    23521 taatcgcttt attaatcata atcaatcaaa attgataact ttaataccac tatttccttc
    23581 ctgatttaag tttgaaagat gatattttac cgtattagga ttctctacaa taactaaagg
    23641 aatatataaa gtattttcaa gtaacttatt atcaatttct actaactttt cccccatatt
    23701 aacttcttga ccttgtttaa cttctaattt aaagttttct ttttttgttg ttgcactatc
    23761 caatccaata tgaataagaa tttgaacatc attttgcaat ttaattccta tagcatggtt
    23821 agtttgagca ataaaactta ttactccttt agtcggtgat ttaagaatat tgtcctttgc
    23881 tatcatagca aatccatctc ccattacctt agttgaaaat actttatcag gaatttctcc
    23941 aagattaatt atttttccat caatgtatga attaattgta cttgcttctt tttttctttt
    24001 aaagaacatt atagacactc ctctacataa ttaactttat tctaattatc attacaaata
    24061 acgatattaa gcatactgca attgaggaaa aaagagcctt atagctcttt ccccattgta
    24121 gttctttaat actgcttatg atttgtttaa ttccaacaaa tttataaata taggtaaaca
    24181 tgataacaat agttattgtg taaatttgga atatctgccc taataagact aaatagaaag
    24241 caatcatgtt ttcttttatc tctttattct tttttatatt gtaaataaca tatgcactgt
    24301 atactgcact aaagttagag attaaattta aacttgcatt aacatcattg tttaaaagtt
    24361 gtgaaaatga aatgtttgta aataatgatg tcaattctaa atacactata tataaaacag
    24421 gtaatattag aaaacaaacc ataaccactg aaagaaatat attttcatct tttaatactg
    24481 ctgttatatt ttttatttta tttgttatca tgtttttgtt ctccttattt aaaagttggc
    24541 cagaaatcct tattagccac aatcatttca tctaagattt cttttgctac ttttgcactt
    24601 ggaacagttt tactcatagt aaacgactgc cataattttt gataactttt ttctatccat
    24661 gcttctacag ctaatttttc agaagcaact tgttgttcca ttaaaccttt ttggaaagtt
    24721 ggaattttac ctatagacat aggttcaacc atatcttttc caacaaggca aggaatttca
    24781 atcattgcat catctgcaaa attttcaata gctccattat taggaacaat cagtaaaaat
    24841 ctttcctgag tattaaatgc taatgcacaa gctaattcaa caataaattg agaatgttca
    24901 cttgcatcaa accatgtatc ccttgctgtg ccatttttta taattctttc acattcttcg
    24961 aatgtatcct tttctcttct atccataatt tcatttgctc ttgtataatt tggattagca
    25021 tgttcaacag tttcatcagc cattaaataa tattttaaat aagtattagg taatgtagtc
    25081 ggttctattt ctaataagtc ctttgctgct ctcatagttt ctaaccaact agattctttg
    25141 tgttgacctt gaggtgtaaa ttcctcatat ccttttttag cacaatattc ctgtaattta
    25201 ggcattaaat catttccttc tttgtcctta atacttgtcc accacccgaa atgattcaat
    25261 ccataatatc taacatcaaa gtctttacga gaatttaaac ctaaaattct agcaaatatt
    25321 tcctctaaac atactggcat atcacaaata ttaataattc ttgaatttgg tcttaataca
    25381 cgacatgctt ctgcaactat agctgctgga tttgaataat taagcatcca agcatttgga
    25441 gaatattttt ccatataatc aatcatttcg attattggac ctattgttct taatccatag
    25501 gcaattccac ctgccccaca agtttcttga ccaacaaccc catattttaa tggaattttt
    25561 tcatcttgtt cacgtaaagc atataaacca acacgaattt gtgccattac aaaatcaata
    25621 tcagtaaatg cttcttctgg atttgttgta taactaaatt taatttctgg atttttctct
    25681 ctaacaatta ttgcacatgc ttcagcaact tttctttgtc tctcatcatt attatcatat
    25741 aatttaattg attcaatagg aaatttagca acactttcaa ttaacattgt tacaattcca
    25801 gcagtataag tactaccccc accagcaatt agtatcctct gtctttttct ttccatcttt
    25861 ccttctcctt tataataaat tttcaaattc ttctcttaca cttggtactg aaagcccaat
    25921 aataatctga atagcttttc cattatgcac taaaccatgt gcacctacta ccttaaaatc
    25981 ttcttcttta gaaataattg agtcatcctt caaggttaat ctcaacctcg tagcacagtt
    26041 tgtaacatct acaacatttt ctgctccacc aactaatttt atgtattcag atgcttgttg
    26101 agaggcttta ctcaatttat ttcctttttc atctttagtt tctaagtatt catttttagt
    26161 atatagtttt gtttcttcat tatcttcctc tctaccagga gttttcatat caaacttctt
    26221 aattaagaaa gtaaataaaa agaaccagat aaatgaaaat ataatcccta caacaacttg
    26281 aacaacatat accttccagt gatacattcc aagaggaagc caatttaata caacccagtt
    26341 aataattcct ccaccaaaat caccaacaac tcctaaggca aacgaaatcg tttgcaagca
    26401 tgcatctaaa aatgcatgta ctaggaataa aagtggtgct acaaataaaa atgtaaattc
    26461 taacggctca gtaattccag ttaatactgc agtaagagta gcaggaatca ttaaacctaa
    26521 tacttttttc tttttttctg gctttgcagt tacatagaaa gcaccaaata cacctaatga
    26581 accaaacacc ttcgataatc cagataatga aaatccgatt ggatacattt cctttagagt
    26641 cttagctgaa gtttgaaagt cctgaatatg agtagcccaa tatactgatg taccacctgg
    26701 aacaacaaca ctatcataac aaattggtgc atatacaaaa tgatgtaatc cagttggtat
    26761 taaaatcttt tgtaagaatg cataacacca aactcctata tttccactat ttataaaaaa
    26821 cgtttgcaaa tgtctaataa cattttgaat atgaggccaa ataaaacaag ttaataatgc
    26881 aactggtatc ataacaaaga aacaaattgc aactacaagt gatgagcctc taaataatcc
    26941 aataaaatct ggtagttctt tatcataaaa tctattatga atataaatga caatacctga
    27001 tattaacaaa gcaccaacca taccagtatc taatgtttta ataccagcaa tgcttacaag
    27061 tccacttcca gcacttattt cagctgcgaa atcaactcca aagctttttc cccaaaaact
    27121 taacatagaa cctacaaaat aattaaaagt caaatacgtt gctaaagcct ccatacaagc
    27181 tcttgcttgt tgcttttttg caagtgctat tggtaaagaa atagcaaata ataatggtaa
    27241 ttgattaaat accatccaag ctccactaga tattacaccc caaaattggt accaaatatt
    27301 ttctggtgta gcaagtgaac ccataattga ctgattttga aatacaattg agaatccaac
    27361 cattatcccg gcaaaagcaa ataatagtgt tggtgtaaac attgcccctc caaaacgctg
    27421 tattttcttc atcatataaa ttactcccct cctcatattt ttagtttatc tttggcctta
    27481 gatatctatt attttaacag gttaataaat atatacaatc tttagggtac atttggagct
    27541 tattcacagt caaataagtt tttgcacatt tttatgttca aattctcata aaaaaaagaa
    27601 tgactacaat ttgcaatcaa tcccttctgt aatcattcta tgccttttat aaatactata
    27661 tttaataaat aataactcaa tcaatataaa atataacatt gtcaatttat aactagggtg
    27721 catttgtaaa aatgagatat tagtcgctga aatataaatt gattcatcac ttaaatcagt
    27781 caatgtatta tttttaaact ctgtaattga aattatttta gttcctatta attttaatct
    27841 tctagcaata ttaagtgtat tctcattctc accacttagg gatataataa tcataacatc
    27901 atttttactg acaatattgt aaaaagaatc atcaaatgtt cttccctcaa aatcatatat
    27961 tatttcttga catgataaga acattctctt tatctgtttt gcaaccacat tttgaatatc
    28021 acctgaacca taagcgtata ttgttcttga ttcataaaga agtttacaca atgcatcata
    28081 atctttattt ttttgatctt caacatactt aattattgaa ttacatgcaa tatcaaatga
    28141 ctgattttct atgacatgaa ccttttctga ttcccagctt aataatactt taaactcact
    28201 gaaacctttt aaatctaatt ttttaacaaa tcttgtaata gttgcacgag acacattaca
    28261 tttcatagca agttcattta ttgacatctt actacaatgt tttttatttg cagttatata
    28321 tttccatatt aataaatctg tatcattcaa tttattataa tttaaaaaaa tcatttcttc
    28381 taatctcata aactattatc ccctttaatt aaaaatcgtc ataaatatta taccaatatt
    28441 caacattaaa ttacagcgta ttcttatatt tactatttag cccataaaat tgactataaa
    28501 aaatactgct ataattgatg tttaaaaaaa tgtagtttta attttattct tttatctaat
    28561 aattaatatt ttcaagttct agtgcttttc ttatgcaatt atcatcttta aaatcagcag
    28621 tccttttaca atcttttact ttaaattctg gaatagtttt aaattcctca tcacatattc
    28681 cattcttatt taaatacata caacttgcca ttctaactat tagaccacta ttttttaaat
    28741 taaacaatac agggtctata caccctccat ctccgccagt agtttcacca actaaagtcg
    28801 caaatttagt ttctttacaa aacattgcaa atgactctga tgatgaatat atttttctat
    28861 caacaagtaa gtatatatta cccttaaatt ttgaatcatc tgtagatttt atagtatagg
    28921 aagtatcttc aaaatcatta aaatctttta taatttcttt aggtgcattt tcctttacac
    28981 ttgctggtaa attttctaca ggatttaatt ttatatttct tgcatttgta tattttttta
    29041 ctatttcatt attatttcta taaattctat aaccatttat tttgacatca ttttttatga
    29101 gtttagatac gattccctgc caatacctat cacttccacc taaattacct cttatatcaa
    29161 taattaaagc tttatgtttt tctaaagtgt taatataatc tccaattatt tttaaatcat
    29221 tatttataga gccattcttt gatgacattg atggtaaata catatatcca atctgaccct
    29281 taataacatc ctttaaaatt aattcttttt ttacaaaaat atcatctggc atttttattt
    29341 taagattcat agagtcatat ctatccacaa cttttttatc attaagaaaa tcataccaat
    29401 cattattaga gtatgatttc ttaaaaagtt catatctttt cttattatct attacttctg
    29461 tgtgtttatt atttaaatca gataatatag atgacagttc ttctataaat tcttcatcat
    29521 tttcagtgtt ttttattcgt tttgtatatt catccttatt tgctaaccaa tcaatattat
    29581 taagtctctt atttacacct agatatggat atcctgtctt tacaacatta tacacataat
    29641 taaagtcatc caccttttcc tcttcagaca actgattctt ttgagaataa gtagaattac
    29701 ctaataagat tataaatgct aaaataatta ctaaaaataa tactttcttt ttcatgtaat
    29761 tctcatccac tttcagattt tatattttaa tacattgtat cattatttta ttatcaccta
    29821 aacagttaaa agaaattctt gaagatatat tccactatta ttctatttaa aaatttttat
    29881 ttgtattttc aaaattattt catgaaagtt ataaaataac aattatattc aaatatctat
    29941 tttactgcta tatcctgaaa gtaaattctt atcagtgata tactaaaaaa gatatgctaa
    30001 aaaatttatc cattataatg acttaaattt agatacttta ctgattttta tttattagtt
    30061 gagaaaggta ttgataatta aaaatattga taactataga aatgattatt ttttatagaa
    30121 attttaagga tataaactaa ttatacttaa gtctatatcc ttaatttatc atgattatga
    30181 gaatttttac aaatacttat ctttgtccgt tttagaataa aaacaagaac atatcctgtt
    30241 attttattca aacatccaag tttaattact acacaattac ttattagaaa ttgtatctac
    30301 ttcatatata tatctgttaa gtatagcttc tagcatttct tgtcttccag acttattctt
    30361 tataactggc atttgcagtg cataagattc taactcttta aatccaacct taccttctac
    30421 tatatcctta cctatacctt cactaaaact tgcatatctt tctttagtaa agttttcaaa
    30481 tacctcatct tctaataatt tatgagctat taataatccc tttgcaaatg tatccattcc
    30541 tgcaatataa gctaggaata agtcttctac ctcaaaagat gctcttctta ctttagagtc
    30601 aaagttaaat cctcctggtg ctattccacc ttgctttaac acttcataca tagcaagtgt
    30661 tgcatcatat atatttgttg gaaattggtc tgtatcccaa cctaataata ggtctccttg
    30721 atttgcatct atactaccta aaacattgtt tattcttgct atatttaatt catgttggaa
    30781 agtatgtcct gcaagtgttg catggtttgc ttctatattc attttgaagt atttatccag
    30841 attatacttt cttaaaaatc ctaaaacagt agcagtatca aaatcgtatt gatgtttagt
    30901 aggctctttt ggcttaggct ctattaagaa ttggccagtg aatcctattt ccttagcata
    30961 atctacagcc atttgtaaga atcttgcaaa gttatccatt tcaagttctg tattagtgtt
    31021 aagtaaagtt tcataacctt ctcttccacc ccagaataca aaattttctc ctcctaagta
    31081 cttagttatt tccatagctt ttttaacctg agctgctgca tatgcatata catctgcatt
    31141 acatgttgta gatgcaccat gaacaaatct tggatttcca aacatattgg cagttcccca
    31201 taataacttt atacctgtct tttccatatt aacttttata tactcaacta tttcatctaa
    31261 tatcttattt gtctcttcta aatctcttcc ttctggagct atatctctgt catgaaaaca
    31321 gaaatactca attcccatct tagacataaa ttcaaatcct gcatcaactt taatctttgc
    31381 tatctcaatt gggtctgtta cattattcca aggtctctct actgtgccta ctccaaatgg
    31441 gtcattaccc tctccacata aagtatgcca atagctcatt gcaaatctta agtgttcttt
    31501 catagtctta ttacctacca cttgttcagg attgtagtat ctaaatgcta attcattgtc
    31561 agattttact ccttcaaatt ttatctgtcc tattccttta aatatttcac tcatttcatg
    31621 tcctcctaat attttacaca tataatatat gtcgtatgtt ttcttaattt aaaactattt
    31681 tctatcttta tttttctttt taagctaatt taattattta tttttgtatt aactacttca
    31741 tctaataact taaagtcatc tttcaaagat ttgtatattc ttttatacaa tctatgatat
    31801 atcttgtatg tatctacatt ttcacttatt ggttctaatt tagttgaagt ttttattata
    31861 gcatcacaag ctttttgtat attttcatat attccagctc ctactaatgc aagaattgca
    31921 actccaagtg ctggtccttc acttgaattt atagtatata catcttgatt aaacatatct
    31981 gcttgcatct gtctccatac tttacttttt ccacctccac ctgaggctct tacttcatta
    32041 acgtctatat taagattctc tattatatcc atacagtctt taagactata tgaaacacct
    32101 tccattattg accttgcgat ttctttttta gaatggattg gagataatcc aaagaacaca
    32161 cctcttgcat aagggtcaag atgaggagtt ctttctccca tcatatatgg taagtaaagc
    32221 aatccattac atcctgttgg tacttgactt acttgattat ttataatctc atatacatct
    32281 tcacctaaag aatttgaaac ttccacttca ctttgacaga aattatcttt aaaccatttt
    32341 aatgacaatc cagctccttg agtaactccc ataacatgcc atgtatttgg tattgcatga
    32401 cagaaagtat gaactctacc ttctttatca atttttggct ctttcgtata agcaaatact
    32461 acacctgatg tacctatagt agatgaaact actccatctt taactattcc atttcctata
    32521 gctcctgctg cttggtctcc agctcctcct accactattg ttccttcttt aagccctgtc
    32581 aaacttgcta catctctagt cacataacct gtaatctctt gtgattcata aactttacct
    32641 aaaagatttt tatctatatt taacttttct agtacttcat cgctccaatc tctttttctt
    32701 atatcgagca actgcatacc acttgcatct gatacctctg tagcatattc acctgtcaat
    32761 ttgtatctta tataatcttt tggaagaagt attttattag tatttatata tatatctggt
    32821 tcattgtttc taacccataa tatctttgat gctgtaaatc ctgtaagcgc tggattagca
    32881 gttatttcaa tcagtctttc ttcacctact aaatcagtta tctcctcaca ctcttttact
    32941 gttcgttggt cacaccatat tatagagttt ctcaatgttt taccttcatt gtccagcata
    33001 actagaccat gcatctgccc tgataatcca attcctttta tacattcact gcttatattt
    33061 gaactttgaa ctacttctct tatagattcg actacagctt tccaccaatc atttgcatcc
    33121 tgctctgccc aacctgattt ctcttgtata agaggatatt catatgtaca actttttata
    33181 atatttccta gtttatcaaa taaaactgtt ttagtacctg atgtaccaat atccacacct
    33241 aatacatact ccaacttcat ccctccttga atgccacttc ataactatcg ttttcctatc
    33301 ctaatttttt tatattttag gtatatttta cttgctttat ttttgttagt atattaaact
    33361 aacttatgaa ctaataataa aatatttaat tatctttgtc aatgcaaaat aaccttttat
    33421 ttttgtgtaa aaagtattac aatattattt taaggaggaa tatcaaattg gttactgata
    33481 aatacactat tcgagaaatg aatgaaagat tggtacttga acaaattata aaaaatggtc
    33541 ctatttctag ggcaagtata gcttctacta taggattgaa taaagcaact atatccgcta
    33601 ttaccaaaaa acttattgat gaatctctag ttcatgaaat aggaattgga aatagtactc
    33661 atagtggcgg aagaaaaccc atattattag tatttaataa atgtgcaggg atttctttaa
    33721 gtatggacat tggatacgac tatatatttt cttctctatc ttacttagat ggaactatta
    33781 taaattctaa gaaattaaca gatatacaag taagtaaaga caatgttata caattgatag
    33841 atgaaattat aaatagttat aacatatcca aaatagacac tccttataag gtaattggtc
    33901 ttactttggc tatacatggg attacttgtg aaaataaagt attgtttact ccatattata
    33961 atcttaatga gattgactta tatagcatcc ttagcaaaaa gtatgacttt cctattcata
    34021 tagaaaatga agcaaactta acagctttag ctgagaatac tttttcaact gtacataact
    34081 cactacttag tctcagtatt cacagtggat ttggttcagg cattataata aataataaat
    34141 tatatagcgg cagaaatggt atgagtggag aaattggtca cactatcatc atgcctaatg
    34201 gtaaactatg tccttgtgga aatcgtggct gtttagaaca gtattgttca gaaaaaaagg
    34261 tatttgaaca gctttcttct ttagaaaata ttcctaaaat agattctgat atagtaaagc
    34321 aactatatta tgaagataac cagaatgcca aaaaagttat tcatgagttt tgtagttact
    34381 taacaatagc tataaataat gctattacaa cttatgctcc tgaaataata tatttaaata
    34441 gccaaataat tagtgatatc cctgagatat tacagattac aaaagatatg ttagttagct
    34501 cttttaacaa aggaataaat atagaaattt catcattagg gtctgaggca tctctatatg
    34561 gtggctctgc cgtaaatatc aagagctttt tgaatataca aaatttaact ttaattaatg
    34621 aaatataagg gttatgacta tatacagcca taacccttta aattatacat tctaaaatta
    34681 gatttattat atagtttatg caagattagc tatatttttt aaaaattgta tatcaattaa
    34741 gtattaacac aagtattttg ttttaaatat taatataatc ttcctactca tcatcagata
    34801 ataaacttgc attttgttca accatagaaa tattatcttt acctattttc tctaattttg
    34861 ctgccaattc ctttgtatct aaaaaagctg attcaataac catacctaaa tttagccctg
    34921 aaataatttt aattcgactg tcatcattgg ctactaataa agcagcattg catggagttc
    34981 cacctagtaa atctgccatt ataattattt ctgaactttc cttgtacact tctaaagctt
    35041 tttttaattt ttctattgtt ccttctattc catcatcttg tttcatattt acagtaggat
    35101 aatctataga atcccctatt atcatttttg cagaatttaa gacttcttca gccatattgc
    35161 catgactcat caaaataata ctattcactt taatacacct ctttaaatct ataagatgtc
    35221 tacaagataa gttttcttat catcaggcgt cattatagtt gtaatttcaa ttccttcatc
    35281 taaaagtctt ttaaatgctt ctttctcttc ttcagtaaca ctgatattag gtcttagaac
    35341 tgttgtatct tttctacttg acatatttcc tacatttata ttatgtattt taaatcctgc
    35401 ctctacaaat ggaataaggt ccacaggaga cttaacaatt aataatacat tttgtccttc
    35461 atactttcct gcagtaatat tttttatagc agtctcttct gtaattatag atgacgctat
    35521 acctgcaggt gtagccattc ttaaaacttg tttttgaaca gaattgttag ctactgcatc
    35581 atttactacc attaatcttg taacacccaa tttattactc cacatagttg caacttgacc
    35641 atggattaaa cggtcatcta tacgaatatt tttaatacct ttcatttcca tatctaatat
    35701 catcctttcc ttattttaaa atacctaatg catataaaat tattgaaaca accattactc
    35761 ctaaaattaa gtatataggt tttatattct ttttaagagc ccaataaaca atcacaacta
    35821 aaattgcagg aactaaccca ggcataattt ggtctaatat ttcttgacct ttcattgtaa
    35881 aatcaccttg ttgaaagttc aaagcaacat tagcttttac aactgaaggt attaatgcac
    35941 ctacaaccat taaacctaaa atagatgtac tctcagttaa aatctttaaa cttttttcaa
    36001 ttgaagatat tagcttagta cctgatgtat agccagcatt aaatagtggt atacttaata
    36061 atttcaatgc tacactcact acaatccaca gtaagattcc aaatggactt ccatctatcg
    36121 ccatattagc tgctatagct ccaaaaattg tccacggaat aacgacaaat aaactatctc
    36181 ctaaacctgc tactggtccc atcaagcctg ttttaattga agcaacagcc tcttcagtct
    36241 cttcacttga taactcctcc attgctacat taatacccaa aatataaggg gcaacccaag
    36301 gattagtgtt aaaaaattgt aaatgattta atacagcact ttgtaacttt tctggattat
    36361 ctttgtatac tacttttaaa aaaggtagta ctgcataaca gtatgccaag gcctgcatct
    36421 tctcataatt tgaagaaaca gaactagtaa aaaaccagcg ccataagaca ctttttttca
    36481 ccttttcatt tgatttattt aatgatacct tatcactcat cttcgtccat acctcctact
    36541 acagtatatt gttgttcttg attttccaaa ttctttttgt aaattataag tgcaattgct
    36601 ccaccaatta aagctacacc taataatggt actttcatat atactgctaa aacaaaacca
    36661 attactaagt aactaaaata ctccttagca ggaagatatc taagtaataa tcctatccct
    36721 actgctggaa gtagtcctcc agctactgtt aaaccacctg ttaaccattc aggtgtatat
    36781 ttcaaaatgg tattaattaa agaaggtcca aatattacag atagagcaac tggaatacct
    36841 gttgtagctg ctgttaatag tactcctaac atttgcatat aggttatatt tttataattt
    36901 ccttttttag ctccatcttc tgctttatga actagccata taccaatagt atttctaaga
    36961 acatctaatt gtaccatcaa taaagcaact ggaataccta tagagattcc tacagatgct
    37021 tcttgcttag tcgtaatagt tataaatgtg gctactatac ttgctgtttg ataatcaggt
    37081 attgatgctc caccaaagtt actaatacct aatgataata gctgtaatgt acctccaata
    37141 tataaccctg tatttatatc tcctaagata agaccagtaa taaaacctgc tgttactggt
    37201 tgatatgttc caaacattgt tgaatttttt tcatagttta taaaaaatcc atatagtacg
    37261 attaataata attgccataa ttgtggctcc attatgattt cacctctccc aaaatatttt
    37321 ttagttcttt aaaattataa ctggaatctt gctttaggaa aataggaatt tcttccagcg
    37381 ggcattcaac ttcataagtt ttcccacctt cataactaac tccactaaat atattttccc
    37441 atgtatgtcc ttttggtaaa tatacttttc tacttctatc tttataattc attattggag
    37501 ctaccaaaat ttcatctcca agcatatatg tattatccac ctcccaagtt ttatcatctt
    37561 caggaaattc ataaaataaa gttctcataa ctggtgttcc atcttcatgc gcttctttca
    37621 tcagtttttt taaataagtt tttaagctct ctctaatttt tatgaatttt gtaagaatta
    37681 cttcaacttc ttcaccataa gaccatattt cattaggagc tccagttacc attgagcctc
    37741 cacctttatt tgataatggt ttactatgag gcaatctatc tccatgcatt ctcaaaattg
    37801 gtgaaaaagt agcatattgg aaccatctta ccataagttc tctaaattct gggtctttag
    37861 gatttcctcc atggaaacct ccaatatcag tagtccacca tggtatacct gccagtccca
    37921 tatttaaccc tgtatttact tgattattaa aagcctcaaa actagaatca atgtcaccag
    37981 accatactaa agctccatac ttttgagctc ctgcccaagc tcctcttaca agagttacaa
    38041 cagactctat gtcattatgt aaaccatcat aaatcatttt taaataatca ataggataaa
    38101 tattaccaca acttaaaaca tttccttttt tatatctata gttatcaaaa tcatacacag
    38161 aatagccagg ttcagctaca tctaaccaat aatagtcaat cccaagttgt ttataatttt
    38221 tatctattct atcccaaaca tattctcttg cattttcatt tgtcatatct acaaagactg
    38281 tatttccttg aatttgcatt gtcattctaa caccacgatt aacattgact aaatagccat
    38341 tttctaaata atcattgtag ttttctgcat cactttgaac tgtaggccat acagatacta
    38401 ttggttctac tgaatactct tctttcaatt ttttaactaa ttctttagga tttttccaat
    38461 aatctaagtc aaatttatat tcaccttgct taggccaatg aaaatagtca attgcaattg
    38521 atgaaagctt aattcctctt ttagaatatt ccttcacaac atctaaaact tcttctgaag
    38581 ttctatatct tagtttactt tgccatagtc ctaaaaggtt ttcaggcatc ataggaacag
    38641 ttccagtaac ttgagaataa tttttattta actcttttgg gctttctcca caagtaatcc
    38701 aataatctat aaaatttgta gaaaacatct tccattctgt catattttta gcaaaagata
    38761 cttttccaat tcccggatta ttccataaaa gtccataacc tagactagaa atataaaaag
    38821 gaactgatat ttgagaattt ctttgggcta actccaaaac agtattcttt aaatctaaaa
    38881 atttatgttg atattgtccc attccaaaaa tcttttcaga aggctcagat tcaaatctag
    38941 tagttacttc aaattctcca ctatagcttg gtcgatattc tcttgatttt aactttagag
    39001 tagagttaaa gtctttggta atctcaattg tccctacatc ttctccacca tcatcatgtt
    39061 ttacagctct taatcgaata tattctttca ataatatttc atttttatca ttataaaaag
    39121 taattctatc tctatggtct aagacagctt ttatctttcc atttttaatg attgcacttc
    39181 catcttcatt tttattaatt gtaatatcat ctttatttaa cttaggtttt tcgttaagag
    39241 catagttttc atcaacaaaa ttttggtcta caaacgacct aatacgtaaa gagttttttc
    39301 cccatgcttc tattcgcaat agttcattgt caaatctttt ttcaatatag tcttcagata
    39361 tttttatcac ggctacctcc taaatcaatg gtataatatt ctatctttgt gtagcttaag
    39421 ttaaataatg tcgtttagta tcgttattta taaattaggt tttatatata attcatttgt
    39481 acattaaact aacttaccaa taatatactt tatttgactt tgtttgtcaa tcgctttccg
    39541 gattttagta aaattttcta atatgttgct tgaaagtcgt tcttaatatc ttttatttat
    39601 acttttaata tctgtgatga tacctatata catctagttt tttttaaaca catacaggaa
    39661 taaaatttgc ctattatgta gataatattg gacttgaaaa tatgtatagt gaccttataa
    39721 atacagataa taatatatta gatattgttc aaaacaatgg attttataat tataaataat
    39781 ttatgaaatt atttaagaaa atatataatt gtataccaag tcaaaaacga caacaaataa
    39841 ataaaactaa aaaagatgtt gtctcaaaat atagataaat ttatttttca ttgctaaaat
    39901 gattaaaata tatttgattt aatatacttg atttaatata aaaaaagagt gtctcataaa
    39961 ctaaaaagtt cacttttaga cactccttta tatatattat caattcattt attacctctc
    40021 tacattttct ttcagctagt agatacatct ttataagtac taattactcc acttaaaaat
    40081 gattcaggta ctgtccatca gtcatatttt tctgccaaat ataatggtgt ttcataatga
    40141 gacaataaat atttatatct ttacttatct tctctaagct cgtcaaatcc aactataggt
    40201 atctctaaat tatattcttt aagtagcttt tctagctctt ctataaaaat acctttccca
    40261 tccaccattt gtatatcatt tattttatcc atcaattcat tgcaaccact tagctcacca
    40321 aaccaacgtt tagaactaca tgtcttatta taaccacaac ttggactacc atctattgca
    40381 atgatacttt ttatatcata atcatttttt aaatattcat taaactgcct tacatgaggt
    40441 attaacattt gcctacattg ttctctaaaa aacaaattgt caaactgttc ttttacatgt
    40501 ccccacctat ttattccata cataatcatt tctgggcatg gtagttgaat tattccatac
    40561 cctttattta ttaaatttat cgctatattt tgtgctccct taaattctga caatccctct
    40621 actttagaat tacaatttaa tatacaatga catactacta caatctctct atttctcttc
    40681 ataataatct ccttagttat tcttaatttt aatgatacta catattttga taattatatt
    40741 atttatttgt tctatatttc caatattcta tatagaaata tacaattagt aatcttttat
    40801 aatctatact atgataaatg tatatatttt tttaggaggt attataattg gatactaaaa
    40861 aagtcacatt ttcttcaata tgcatagtta ttaatattgt cttaggtatg gttatatcta
    40921 tgataaatat accattatta tttttagata cagttggtac tgtacttggg gctgtcgtat
    40981 taggtccttt ttggggtgct cttattggtg ggtgtacaaa cttagtttta ggtgttatat
    41041 caggtcctac aaatatacct tttgctcttg taaatattgt tcttggtctt attgttggat
    41101 atatttctaa gaaaaaaggt tttggttata aagaagctat tattacagga gtaattttat
    41161 ctattgtttg tcctttaatt ggtactccta tttcagtttt attgtttggt ggtttaagtg
    41221 gaagtggtgc tgatttattg gttggttttt tagttcagtc tggtcagaag atatttactg
    41281 ctgcgttctt tccaaggatt cttagtaata tagtagacaa acctttgtct tgtattatgg
    41341 tggtatattt tataagtaaa atgcctaaag gttttataaa acaatatagt aaaaatactt
    41401 ctagttcata ttaataaatc atttattatg taagatttat tactctttaa aatgctatat
    41461 actcattttt atataacatt tttattaata atttaattag atagtatttg tattatttta
    41521 attaaacgta acctcttgat ataaatttga gctataaatc tatatcaaga ggtgctattt
    41581 tatttttaat ataattaata ttctattacg caaaaaatgc atatatttca ttattttatg
    41641 gaaaatatta cttcatttaa ctctatatca aactcattaa gtaaaaatct aattatattt
    41701 aatttagcct ctgtatttaa atttgtttct aaatatatat tttctgatat tttaatacct
    41761 tttcttaatt tatatacatc tctagactta atattatcta taaaatctct tttataagtc
    41821 ttgtctacaa tactgttaaa ccttacagaa tccaaatcat ataaagtaag agcaacttgt
    41881 tcataaaatt ctgtccaatt tttagcctta tatgactctc ctaatatact aaatgatact
    41941 atactttcat ttgtaaaatt aacatcatca tcctctaacg taaatatatt ttcactgtta
    42001 cttggaggtt catatgtaac acttggatat ttccaaattt ctacagctct atctagtaat
    42061 atcttagttc tattttttat ttcttcttca ttccatttat ctatagatga aatatattta
    42121 tttagataaa gcctactatc tttaaatcca tcttccattt ctttcttttc ttcaaatgtt
    42181 ttattactta gttttgaatt atatcctgtc aaagttaaat ttccaattgt atgtaaatat
    42241 ttatcatgta tctccttata gttatctcct agtgattcct tccatttatt tgttaatgtc
    42301 tgtggcatta tatgctctat atttagcata ttattattga ttaaattttc taaatcaaca
    42361 atttctttat tattataatt ctctaacctc tcaagtatat ataacttatt ctttgactta
    42421 gtattatata tatctttagt ttcaaaagca tttgaaaatt cactgtcagt aggaaatctt
    42481 tgagatgatt tcttatttat aaaaatatat cttaatatat tagaatagtt ttctttataa
    42541 tcactaaatt ttttaatttc ccttcctaag ttcataaata ctttattcag tgcattcgga
    42601 ggtacatcac atactattct tcttaatata aaacattcta ctaaattaag ggattctaca
    42661 agtacttttt tatttattat accttcatta taatcattaa ataattctaa tataaacgga
    42721 tatgatacaa atatttcaag tttgtttatc cttttcaaaa ctttgtttac atcattatca
    42781 tcagtacatg aataagatat ctctctataa tagttagaaa atttaagtaa atcttttaat
    42841 aaaatttcta tatctatacc attatctgat acataccttt taaaactaaa atatacttta
    42901 tttttattcg gtatacttct ctcctttata gtcaaatagt ctcttataaa gctacttacg
    42961 ttgctacttg tatttttttc aattttatac caataattat tataaaattc ctcttgtaac
    43021 ttagagcttc tacccattaa cacaaagttt cttactctat cagcttcact taaatctaag
    43081 ccagttgaat ttagactttc aaagattaat tgagggtcat cttcaccatt ttttaactct
    43141 atttctacta tagttaattt ctgtatagca tcaaacaaat catctattga tatattatct
    43201 tcttttattc tattataaaa atataaataa tttgaaacta tattagaatt tctatctgta
    43261 ttcatttctt cttcaaatag ttcatagtaa gcttttctat cttctgctat tggttttaac
    43321 tttatttttc catctttatc tcttgagtgc ttgtttataa gataacactc cttaatctgt
    43381 tcttctgttg taataattcc ttttgattct ccaaactctt ttattatttg acacatggca
    43441 atcaataata ttgacacagt agtcactctt tgttgtccat ctattattaa atattctttt
    43501 cccatactat atatagatac aactgaccct aagaaatgag ttctaaatcc agaatctatt
    43561 atatcctcta aatcatcaaa caatctttta cattgttctt tcttccagtt ataatttctt
    43621 tgatatacag gcactacaaa acttttgttt gacccctcta aataactaag aaattcaatt
    43681 tctcctgctt tcatattaac tccccctata agttaaataa attccattca taactccatg
    43741 tatctatata ttatatcaaa attttgactc ataaatgtat atgaaagcct tattatatac
    43801 ctttttatac ctatttttat tttattaaag taaatacatg attattctat aaaatataca
    43861 aatacttaat tttaaaaatt attatttaat cttcttcatg agtaattcat agttatttat
    43921 caattaaaaa gagatattgc ataattattc aatacctctc tttgtatatt tacattatcc
    43981 atatctagtt atctatttca acccaatatt agactaccta ctaataaatt tattctctac
    44041 ataattaaca ataattttgc actaaataac atcattagcc tatctctgat gcattttctt
    44101 taattttatt tatagtttta atcaatttat ttctctcttc aatatgattt tcaaataaat
    44161 caattatact tccaacagtt ctaaatgggt cttccatcaa cactttgtta tcctctataa
    44221 atccattctt gactacataa tcgactataa gtttaacaaa atgtatttgc ttagtattaa
    44281 aactcttatt atttaaaaac tctgaaaaag cttcatttgc agcttctcta tccaatccca
    44341 ctagttttct cactaattga cttactggag tatctccaaa ctccttttta taatcatcac
    44401 aattacctaa ctgctttaag agtatttcct ccaacgtttc aacatcttgc tttgttatct
    44461 ttttattatt tcttaattta aatattgcta attcatcttt atggctattt aaataatact
    44521 ctaccttctt tttataattc ttaagattgt ttgcattata tacagaatca tttctatctt
    44581 ctgctacaat catatcttca aaacttgtat aatatatctt ttgactagac ttttcaagat
    44641 acttaataag ctctcttaat gatatacgta cttcttctac ctcaaatata tctgaatctt
    44701 cccaaaaatc ctctgtcatt gctttttcaa tagtatattt ttgttgctgg atctgtggta
    44761 tagtcccaag tttcgaaagt ttttctgctg taaccattac atgccttatc cctttacttg
    44821 cattattatt ttgtaagtat gcaagttgta tattatacat aactacatca aatcttttag
    44881 ccaattcatc atcactatat gaagttatga gtggtgatat atattctctt atctcatttt
    44941 gtgctactgc tccaatattg ctccaaacat tttcattttt atacttatgt acataactta
    45001 aattcatcct aactatataa ctatcctcat ttaaagcttt tacagaagtt ataagttctt
    45061 ctaacaattc ttttctaagt tctgcatact taccttctat atatttaata tcttgaagtt
    45121 ctttaaccat acttaccttt atattaaata atttttcagt aagtgtttct gctttatttc
    45181 cctcaaatcc tttaggatta aatttaaaaa attcaaaatt attacaaaaa tcaaatatta
    45241 agaatctttc cttatccata tcaacaccta ataaatctgg acataatcta gttcctctac
    45301 ctatcatttg ccaaaactta gtcttacttc tcactttctt gaaaaaaaca agatttagga
    45361 tttcaggtat gtcaattcct gtatcaagca tgtctactga aactgctatt tgaggtaatt
    45421 tattcttatc agaaaaatca tctattatag aatctacata atttatacta tagtcaactg
    45481 cttttacaaa gttcccacca tactttggat acagtttatt aaatctttca actattgccc
    45541 tagcatgctt tgtattcttt gcaaaaatta tagtcttacc aatcttttct tctccttcta
    45601 ttttcaaccc ctctgtcatt agcttattta aaactaaatc tattgtgtca gaattaaata
    45661 gccactcatt tactgcatta ttccctattt cgtctccaat actctcatca tcattaaatg
    45721 tattttcata ttcttccttc tcttcatcag aaagctcatc atacttaatt ccatcttcca
    45781 taatcttagt cttaaactca atactagtat aatctactaa atatccatcc tcgactgctt
    45841 tattatactc ataagcatat gtaggtactc cattttccat gtcaaaaact gaataagtat
    45901 ttttatctat ctcatccttt ggtgtagcag taagacccat taagtaagaa tcaaaataat
    45961 caaagattga cttatacttt ttataaatac ttctatgcga ttcatctatt ataattaaat
    46021 caaaatgacc aggtgtaaac aatctctttc catccttaga cttcgtatca tcaattgcat
    46081 tcatcattgt tggatatgta gaaaatatca tcctagcatc ttctgggctg tctttgctat
    46141 ccaataaatt acataacgcc aagttaggta atagcttagt aaaacttttt ttagcttgct
    46201 ttaccaatgc ttttctatct gctagaaata atatattttt aatccaatta tgtcttgaaa
    46261 gtacatcaac tatagatata gcaattcttg tttttcctgt accagtagca cataccaaaa
    46321 gagttttgcg ttgcttattt tcaagagcct cacatacagc cctaatagct tctttttgat
    46381 aatatctatt ggatatttca tcatttattg ttacagaact taaagacttc ttactctttc
    46441 ttctatctat cataagttgt aattctgatt ttttataaaa tccataaact tttctatctg
    46501 aatagtcatc ccaaatatac atatcaaaac cattcgtcaa aaatattact ggtctttgac
    46561 tatatctctt ttccaaacaa tctgcatata atttagcttg ttgttgacca attttcgggt
    46621 ctttgctcgt tcttttcgcc tcaactactg ctaatggctt accattttca ccataaagaa
    46681 cataatctac atatcctaca ccactttcat taggcatacc ttgtacttct atttcctccc
    46741 ctatatcttt tccaaattcc caacctgcaa gctttaattc tatatttata tatctttttc
    46801 ttgtctcaaa ttcgtttact tcgtctatct tgaaatcgta gtttacagta ttaacttttc
    46861 tcttttcagt tagtgacttt cttaatttct cattttcttt tattacttct tcaagctttt
    46921 tatcttttga acttaatctc tcataaagat ttttaagctc gtctggtctc gtccttttct
    46981 cttccccatg aagtaataaa tcttcattaa agtcttctgc tgtatattca tctgaataac
    47041 aatagtctat ccaactaaca aattgatgca aattgttaag tgaaagtatt gcttctcctc
    47101 tctctatgtt cgcactagta tgtacagata aattacctaa tttaactata tattttaata
    47161 aaggtaacat atcatagtct ataagttcta taaaactatt attatgaatc aacgtactaa
    47221 gattatcttg ataaggcaat actaaatcac tatcattagc atatagccat tttactgcaa
    47281 gctctaaagc tcttcttgtt atagttgcac aagtagatgg gctaactagt atactttttt
    47341 ctgcttctaa gcaagcagta ttaaaactat tgaaattttt cttcttttgt aaaaagtcaa
    47401 aattacccaa ggcttttctc ccccttttgt cccttagtta aaataaatct ctctaaaaac
    47461 tatttcttac agctgtttct tatactaaca aatacttctt cattttctgt aaacaattcg
    47521 tacatatctt caaactgtgg tatatcatat ccatgagaat catcatttct caattttcta
    47581 agtgtttcta taactataga agaattttta ggtaataaat tgtgatactc acaagctaaa
    47641 aggtagtcat aaaagttttt agattttatg tttaaatcaa ttgatttata atacaacatt
    47701 gcttttgtta attctaaaaa tgagaccata tagcttttaa aaccttcttt tatgtatcta
    47761 gcccataact caggcatttc ttccttatca tataagattt tgaagttttg caggtcatat
    47821 aagcaagaac caaaatccct atttacttct tctattgagt tccaagataa tttgtttcta
    47881 attaccatac atgtccctcc aatctaagat atctattaca tcactgtttt caaaatagaa
    47941 tttatttata taatccttaa aatctttaga ttcataaata acttcacctt ctaaaatagc
    48001 ttttttaagt gctattgtat aattatctgt aacaattttt aggtctacat caatgtctaa
    48061 tatatttctt agagcttctg tcttagttgc aagttctgta attggtactt ttttgatagg
    48121 aatccaagct atgtctatat cgctttctga tgtatgttta tctgttccat aactaccaaa
    48181 tattatgatt gctagagtat tttcttttgg aaatacattt attattgagt ttttaatctc
    48241 atttggtata tttctcattt aatcacctct tgtttattag gtaatattgc ttaattgaat
    48301 ttatatccat aatcttttaa tctatttata catatttctc tttcttcatc agtaaacaac
    48361 tctttatact tttcttttaa tactaatact tctaatgata aatctaatct cttacactcc
    48421 catagccttg taaatccttc agtagctcct tctttattga ttaattcttt agcagctaat
    48481 aaggctcctt tgttatttat cagttgtaaa aatcttgttg gcttatagtt acattgtaaa
    48541 tcagcttctt tatagatatt taccatgtca tgatataaat ctagctctat ttgattcata
    48601 gattttattc ccccatttta atacttgtat ttcagttgaa caattctcct ttaaaagctt
    48661 tttgcattaa tgagttaaag ttatcttcta gttcttttaa gctagtttcc atttcaaact
    48721 tcaaagagtt tacttgttta acgaagttgg caaattgatt ttgaagtcta ataggaggta
    48781 caataatatt tatttttcta acagcatctt tagttatcgt ttttgttaca gctcctctta
    48841 ctttctcttt tattttactt tccatatagg atgttagtaa aaggttatat aagaatatat
    48901 gattcacttt atcttcatta aatctaagca taaattgatt catagctaaa gatactggtt
    48961 tatttaaaaa tggcattaaa taaactttac ctgcactacc tatcttattt attataacct
    49021 caccaccaaa cacctttgat ttttcaagat aattatatgc atgttcatcg atatacttaa
    49081 cacctttttc aaagttatta ttttctaaat ctgtagttct taccattaag gcataacctt
    49141 ttgtatctaa aagagttaca ttatctctta aggtttcata actaccattt gaatgataat
    49201 cagttaaaac atctaaatat ttccctattt ctgaaatttc ccagtttttt tcgttctttg
    49261 atggggtacc aaacatctca ataaatcttg atttaactaa ttcatccaat acttctattt
    49321 gctcttttct tttatctatt aactcttgag ccttgtctaa aacacgcact accttttctt
    49381 gcacttttaa attatacatg cgtattttta tattagctaa tccttcatta tttaaagctg
    49441 attgtgtagc acctttactt aacctatttt tttgatttag aaaataacta ctatttaagt
    49501 aatggtataa atattgaggc aatatttctt ttgatggttt taaaacataa aagccagtcg
    49561 atactattat atttttatta gttttattaa taactagtgt tttctttgtg tccttcattt
    49621 ttgcaaatat aacttctcct atatttacag tttgatttgc tctagaaggt ttattttcat
    49681 aagtaactat ttctagattg cttatcttgt taaaatctaa gtttccagta ctaagatatg
    49741 agcgttctcc atcaaacttt tttacatttt ccctgcttat actaacaaca tctaaaattt
    49801 ttgcttcatc aaccatactc tacacctcta acattctttc tagttcctct aatccatcca
    49861 ctatctcttt ctctaacacc ttaaccctac ctataataac actaggagca tcataaacta
    49921 cttcctcata cactacctct ttatacttat taatagataa atcataccca ttctctctta
    49981 tctcttccac atcaacaaaa aagctttgct ctgttctttt tctatctact tccccatcaa
    50041 gattatcaaa tctcttaata atatcctcta tatcactatc ctttatctca tttctcttat
    50101 catccaaaga ataaccatca gctttcatat catagaacca taccttatca gttccacctg
    50161 tccctgtttt agtaaatatc attatagctg tagatacccc tgcatatggc ttaaatacac
    50221 cacttggcat tgatattata gcttccaatt tatgattatc aactatttct tttcttatcg
    50281 atttatgtcc acctgttgaa ccaaacaata ctccatctgg cactatacat gcgcatcttc
    50341 caccaatttt taaaactctt aaaaaaagtg ccaagaataa taactctgtt ttctttgtct
    50401 tagtcacttt taataaatct gctgacactg cttcataatc taaacttccc ttaaaaggag
    50461 gatttgctag caccaatgta aacttatctt tatctgtatt aacctccgat aaagaatcct
    50521 tatactctat attaggattg tcaacgccat gcaacatcat attcatagca cctattctaa
    50581 gcatagttct atccatatca aatccataga acataccatt attaaaatgc tccttcagcc
    50641 cttgcactaa gaaaagactt gaatgattat cccttaagta ctgttgtgat gatactaaaa
    50701 aacctgccga acctgctgcc gggtctacta taatatcttc tggtgttggt ttaataagtc
    50761 ttactatcat atctattatg tgtcttggag tcctaaattg accattagta cctgctgtag
    50821 ccactttgga taataaatac tcatacaaat ctccctttgt atctctatcc ttacttaatt
    50881 ctaaattact aataccatca actattttag ataacataag aggcgtagga attttaaata
    50941 ttgcatctcc catgtacttt gcataagctg attctttatt tccatgtaat ttttttatga
    51001 aaggaaacac ttcattttgt actatttcat acattttttc tgagtttcct tcattagaaa
    51061 acttactcca tcttaaatgt tgatgttcat catcaaatat cttttcaaaa gaaacaccca
    51121 aaagagttgc ttctgcttca ttttttgttt ctacttcatc caatccttta ataaataaaa
    51181 gatatgtaaa ttgttctata acttctaatg gattagttaa tccaccagtc caaaatgtct
    51241 cccaaatctt gtctacttta ctccttaatt ctcctgtaat catatatgac tttccctcca
    51301 gtgttcataa aataatttaa atatatattt tagtcgtacg ccttaatagt tagtgtctta
    51361 tgttaaatcc aagtttttac tacacaatta ttaaattatt tttcccattt acatatttta
    51421 gctaaaaaac taatgcaata ctcttatttt atgattatta tatataccat acaaaattat
    51481 tttatcatat atccatcata gaagtcatct acctggataa ctcttaccat attataactt
    51541 tttaatatta atttaaactt agaaagaaat tttttattta attatatcat cttccttatt
    51601 tcaaatttct caactacaat cctaatcaaa aaataaaata agatgctgtc tcaaaataga
    51661 tataatcttc ttttttattg tcagaatgat gaaaatatat ttgatttcac acaaaaaaga
    51721 gtgcctcatg aactaaaaag ttcattttga gacacccctt aatttaatct tacttattct
    51781 ttccctttat tattaacact tcactgtccc tattgctttt cctacacatc cacaaacttc
    51841 catcctactc ttaacaaaat ctttaactga ctctaaacct tttttaccat atttcttagg
    51901 gtcaattacc tctgggtcag aattaagcac atccttaacc ccattgctat aagcaatcct
    51961 taattcagtt gcataattaa ctttgcaaat acctcttttt atagattcct taataacctc
    52021 atctggtatt ccagacccac catgtaatac taatggaact gatacaacct ctctaatttc
    52081 agataatcta tctaaatcaa gctttggctc tcccttatat agtccatgtg ccgtacctat
    52141 tgctactgcc aaagatgata cccctgttct ctctacaaac tcttttgctt ctaatgggtc
    52201 tgtatatgct ccaccatcac caccatctaa atcgtcttcc ttacctccaa ctttgcctaa
    52261 ttcagcctca acaggtatat ctgaaggcat acatgcatct acaacagatt tagatattga
    52321 aatattatct tcgtaacttt catgagaacc atcaatcata atagaagtat atccaactct
    52381 aagtgcctgc atagctagtc caaagcttga accatggtct aagtgcattg ccactggaac
    52441 acttgccttc tctgatgcta cctttacatt cgctaaataa taatctagcc ctgcatactt
    52501 tattgttgaa ggtgttgttt gcaatattac tggtgattta agttcttcag cagcctctat
    52561 tactgccata accatctcca tattttcaac attaaatgca cctactgcat aatgcccttc
    52621 ttgtgcatct aataatattt gtttagttgt cactaatgcc ataatttctc ctcctatatg
    52681 tttatactga tttgatttct tcgttattta attttgatac tatttctcta cttgttttgc
    52741 tatttaataa ctcatttaaa aattcttcat tcattaattt tgaagatagt tgagataatg
    52801 tttttaagtg taaattatca ccattatctg tagctgatat cataaatata atatgtgcca
    52861 agcttccatc ttctgattca aagtcaaacc cttcttttga tacacctact gctacacgtg
    52921 gtacctttac tgcatctgtt tttgcatgtg gtatcgctat ccccatacca aaacctgtag
    52981 atgatatttc ttctctttta aggatttctt ctttaaactt ctttttatct aaaagaacac
    53041 cagatttatc aagtattcca atcatttcat caattacatc tgttttattt tttcccttaa
    53101 catctaaaat tactgtttct tcgctatata aagagatatt attagatacg ttttccgatt
    53161 ctgcactttc atttttatgt ccatcttttg ttgcatttgt attttctata gtatttttct
    53221 catttactac tttaggtgta accatcatat aaagtacagc acctactaat gaacctacaa
    53281 atatacaccc tacccataaa agtggcttat tgactaatcc tagaaccaaa aaccctccat
    53341 gtggagctgg tacttctatt ttcattatat aagttaaaat tgatgatatt gatgatgcaa
    53401 tcataagtac tggcaacact tttaatggat tttttgctgc aaaaggtatt gccccctctg
    53461 ttatatgagt actacctagt atataattga ttaatcctgc tgctctatct tcttctgtaa
    53521 atctattttt aaataaagta gatgctattg ctattaccaa tggtggtgtt atacaagctg
    53581 cagatacacc tgccataaat aaataatttc cctgtcctag aagcatagtt ccagttacat
    53641 atgctgcttt atttactgga cctcccatat caaatgctga catacatcct attactattc
    53701 ccaaaattat aggacttgaa ttttgtaacc ccgatagaaa gttcatcata gcattgttaa
    53761 gtgctgaaca tggtccacca agtaacaaca ttgctacacc cacaagacct acgctgacaa
    53821 taggaattat aaaaatcgat ttaagacctt ctaattgtcg tggtaatttt cttaacaaat
    53881 gtacaaatag tttaactaag taacctgcta aaaatcctga tatgattcca cctaaaaacc
    53941 ccgaacctgt atcaaatgat atcattcctc caacaagtcc tgccaacata ccagctcttc
    54001 ccgatataga ttgagctata aatgctgcca atacaggaac catcaagttc atagaatatc
    54061 caccaacaga ttttaatgta gctgctattt gattatattg ttctgaattt gggtcaaatg
    54121 aataaatccc ccataaaaat gatatagcag taagtactcc acctgctact actaaaggta
    54181 acatgtgaga tacaccattc attaagtctt tatacaactt ttgaccaaac gataaatttc
    54241 cttcttctgc aattttactg cttgataagt ttccttttct aatagctact tttccatcaa
    54301 tacacctttg tataagttca ttagccttat gtataccttc tttgacaggt acttctatta
    54361 ccggctttcc attgaatctg tccatatcaa catttttatc acaagcaact attattgcat
    54421 ctgccatttc gatatctttt gctgttaact tattttctac acctatagct ccattcgtct
    54481 caacttttat gtcacaccct aattcccttg ctgaattttt taatgcttct tctgccataa
    54541 aagtatgagc tattccagtt ggacaacctg ttacccctag aatcattttc tttcccatct
    54601 ttataccacc tttctgactc ttatattttt tatataatct tccacattct ccaaattacc
    54661 tataccatta ctttcagcca cacttgctcc tgttgctgct gaccttttta atgcttcttc
    54721 aatatgttct ggattttcca accatatact taaaaaagca gctaatgcag aatcaccagc
    54781 acatgcagag ctgactactg taactggttg agcactagca taataaattg attttccatt
    54841 ataaaaataa gaaccttttt ctcctaaagt tagcaatata ttttgagcac cttttaaatg
    54901 cagtaattta agtacatcct taatatcttc ttcatctctt acaataattc caaatatatc
    54961 tttgatttct tcatcatttg gttttatcaa atatggatta tactgtagta actcctttaa
    55021 ttttggtgaa cttatatcga gtattgtctt tatactttta tttttacaaa ttttaaatat
    55081 atcctcatag taattatcat caataccagg aggtagactt ccacttattg ataagtaact
    55141 tatatctgct aatgactgta tcttatctag catatctagt ttttgttttt cgtttacata
    55201 tgacccagag tttacaaatt taaattcatc acttccatca tttaaaaata tatttatacg
    55261 agttgtatct tctacccaag taggtaatac gtcaaatcct ctcttttcgc tttcttcaac
    55321 tatatatttt cctgaaaatc ctccaaaaaa tcctaatatc ttagattcta taccataatg
    55381 acctagtaca aaagttacat ttaatccctt tccattagga gaatatacag catttgatgt
    55441 acgatttact aattttctct ttatcccatt agtagatata ttcatatcta ttgcaggatt
    55501 cgtagttaat gtatatatca ttgtcttccc ccttgcttgt gctgtgtatg ttttcattat
    55561 aataaaaaag tctatgaaaa tcttttcaca aatagaaaat cgattttcat agacttttca
    55621 atttaatttt cagaattatt atatctgacc atataatcta taattatcct agatataata
    55681 tacaagggca atctggaaga tacttcatat tcagaaattg atatatgttc atgtttgtat
    55741 cctacaatat ataaatccga atactttata agttttgcac tttcactaca acagcaagtt
    55801 ataaccttag ctccaactaa attggcattc tgtgctgatt ctacaagctc tatggtattt
    55861 ccattcaatg aaaatatgat tataagttcg tcttttttta ttgatttaga ttttattttc
    55921 attatgttgg ggtcatttat aaaaacaaca ttaaaatcaa gtaattgcaa tttaagacta
    55981 aactcttttg ctacatattc agtaagccct cttgccaaaa tatatatctt actagattta
    56041 tttatagttt ttattatatt gattagtgta gttaaagata tttgttctat aactctctgt
    56101 gcttctataa aggatttatt tattatatcc cccatatttt gtatatcatc attttcatct
    56161 tttactgtta atctatacct aagttcattg aatccattta aaccacattt tctaattgct
    56221 cttgaaacgg ttgctggaga tgaatatgtt tcatgagcaa tctctactat agataattct
    56281 ggtaatattg attcattttc atttataaat ttaattattt caagttccgt cttcgttaga
    56341 ttttcagaat tacttttgtt tagctcaatt atcatatgtt atctcccctt atataagttt
    56401 tatttgtcta aatttatcga gtaatataat atattacctc ttaactactt atttttatat
    56461 acaattaaga tttagtcaat gtctatatat gtaaatttat aatataataa ttttatgctt
    56521 caattaatta tgtaattatt agagtatttt gtaataaaaa ttggagttac tcaattactg
    56581 aaactgagta actccaattc ttacagcctc aaattaactc gaattattga aaatgattca
    56641 taaacattat cctatactct cacttatcaa tttatatact tgagtaatac ctttttttat
    56701 taacagaaat catcttacta acaattgaaa ttgtagttcc agtacataat attgaaaata
    56761 tagttccaaa ccctaaattt ccgcctaaat atacacctaa aattaaaaat attaaatctg
    56821 ctatagtttt taaaacttta tatggatact taaatttgcc ctcaatatag attaatatag
    56881 catctaaagg gctcattcca atgtcaaatt ttataagcat tgcaaatcca ctacacataa
    56941 gtatatgtcc aattataaag ctcattattc taatgataat ccctaaacta cttatattaa
    57001 aatctaataa taaatatata tacaaatcta taaatattcc tgctactaat acataaacac
    57061 agcttcctaa tcccaaactt tttttattca ataacaatgc tataagtaat agagttccat
    57121 tatatattag ccctgctatt gtataactta tacctaactt tatatgtata ccctcattta
    57181 aaagtgtaat tgcatcacta ccaaggcttg actgaagtat aagagatata ccacatccca
    57241 gtatatttat aattaaaatt acaaatataa atttttttat gacattcata attaataaac
    57301 caccttattt ataattataa tccctcttat aaaactgtat taataacata gtatttataa
    57361 gagggattat ttatatttaa aaactatcta ctttttcttt taattcttct ccattagttc
    57421 ttattacatt tttataccaa taaaaactat cttttttgta acgttctttg cttccatttc
    57481 cattgttatc tatatctaca tatataaatc catatctttt ttccatttct tgagatgaac
    57541 aacttactat atctattggc gaccacatac aataagctaa tatttcggtt ccatcagcta
    57601 tagcttcacc tatttgttct atatgttttc ctaaataatc tattctataa ctatcatgaa
    57661 cttttccatc ttcaaattta tcatgcattc caaatccatt ttcagctatc attattggct
    57721 tttgatatct atcataatat tgagataaag tattgtataa tcctttaggg tcaattgccc
    57781 acccccaagg atttgctttt aagtattgat tttttacatt atcaattgga ttcatggtat
    57841 ttttacttgc tgatactgtt gtagagtaat agtatgatag agctagaaaa tccatagtat
    57901 tctcttttaa cactttatca tcaccttctt ccataactat atttatgtta ttttctttga
    57961 agaatctctt aatataagct ggatactccc ctctaaaact tacatcagta aaaaaatatt
    58021 gtattctatt tctttttaaa gcaaatacta cattttcagg gtcgcaatct tctggataag
    58081 atgtacaatc tgccatcatc atccctatca tcatatctga atttatttct tttccaagct
    58141 tcttagttaa agctgtagcc atgaattgat gatgaatagc ttgatatttg gcctcttcta
    58201 catcatctac ctggtctaca caaaatgcaa ctgaattaaa tgattcatga tacattaaat
    58261 ttatttggtt tataactatc caatatttaa ctttatcttt gtatctattt aatattaatt
    58321 ctgcatatct aacaaagaaa tccactactt ttctattaga ccatccttta tattttaata
    58381 ctaaattcaa aggagtctca taatggagta gtgttacaat aggttccata ccattatcta
    58441 ttacttcatt tataagatta tcataaaact ttaatccctc ttcattaggc tctaaatcat
    58501 ctccatttgg aaatattcta gcccaattta ttgaaaatct aaaacacttt aaccctagtt
    58561 ctttcaaaag ctttaaatct tctttgtatg tatgataaaa gtctattcca ttacgcttag
    58621 gataataccc attattatct ttcatagcaa actttatttt atctacagtc atatcagact
    58681 cgtaatgttt agatatatct ctatctttat catacatatg tacatcagct aagcaccacc
    58741 ctttgccacc ttcattccaa gcaccttcta attgattagc tgctacagct ccaccccaca
    58801 aaaaatcttt aggaaactta ctcaatttaa tcactcctta ttttatttat ttaaatcatt
    58861 tactattatt taccttatat tctatagact ttactattcc tactaaagac atagttatat
    58921 ttaactcgct gaatattgtc ataagagtat cttgagcatg tgcaaataaa agtgaatgtg
    58981 ctcttttttc tccactagct tccccttgta taatgttagt ttgagctcta tgtgcttctg
    59041 tcataaactc ttttgcttta gctagtttta aatcagcatt tttataatca aacctttcta
    59101 aatcattaag agcatgttta atttctgttc tagcctcacc tgcacgaagt attatttgca
    59161 ttgctacttc tactaattct tcatctatta catgttcttc agttgtcata tttataattt
    59221 cctttcaaca tctaaattta agcttcttga ctctctaatt ttagttcttc tttttcataa
    59281 gctttaaaaa atggatacca tatcatgaat agcaatacta tatttattgc taaaacaata
    59341 agccctctaa catcttgatt taccataaaa gtagatatac caaaaggaag ataccataaa
    59401 ttaaacacct tactcggaat tgtcacaaat cccatactca ttgataagta agtagttatt
    59461 gatattacta ctgttcctat ccacataggt aacattaaaa atgggttcca tgctactgga
    59521 gctccaaaca ttactggttc atttatgttc attatagaag gaacgataca ggctcttccg
    59581 attgctttta ttcttccagc tctagataaa cacatcatta gcactagtgg taatgttgct
    59641 ccccacccac ctaaagttat ccaacctgtt tgaacaactt cataagtata tatattagtt
    59701 gcaagccctc ctgatgctac agctgctgca ttagctgcaa ttgcactaag ctgaattgca
    59761 taagttattg gggataatac ccatccactt atacctaaag aatataaaaa tactactaag
    59821 aagtttaata gtacaaatcc aggcaatgtt tgtgctatat ctgatactgg tttaaatatc
    59881 ctaactatta tttcaaacat atcaaagtta agtccataaa ttagtcccca acctataaac
    59941 attattactg ctataggtaa catactatca aaccacttac ttacaaaatc aggaagtgct
    60001 gaatcttcac caaaaaatga gaaagaccca aataaagaca ttattaatcc ggagaataat
    60061 cctgcaacta gtgctacaag cattccttct cctccaaatc tattgaagtt aaatatagct
    60121 ccttcattcg taatctctgg acgaatcatc attaacatta atccagcacc tgcaagacca
    60181 gctactacac tcatactttc aaatttctta ttcttcatta tttccatagg taataaaaat
    60241 gctataaata gtcctaaaag tccaaatgta tattgattta ttggacttaa atcaggtaag
    60301 aaacttatgt aattcttcaa gacagaaact atagttacta aagaacctac aaataccata
    60361 ggcaaaactt tcattatagt tgattgaact gattgtaccc atatattctt agttatctta
    60421 tttacaacag gagtaaactt ttcacttaac aaatctataa atttattcat aaacaatctc
    60481 cccatagata ttttatttgt ttaatattaa ttctaatgct tcttctaaag cctttacacc
    60541 atctaatctt ccatatgctg ttttagatat acatgctact ggaacattat attcatcagc
    60601 ttttttttgt atttcatctt tcatataatc taaatgtggt cctaataata aacaatctat
    60661 ttctggtaaa tatttatcta tctctgactc acttctagct tttatatctg cttctatgcc
    60721 ttttttcttt gcactctttc tcatactagt tgccataaaa cctgtacttg ctcctgagcc
    60781 acatgccaac aacactttta tattcttcat aacaatacct ccagtatttt tattcattaa
    60841 tttatttctt aatgaatttt tatttgattt gattgtattt atattgtact tcctaaataa
    60901 tttcctttca cataaatata tttcctaata ataggaaatc atttactctt aaccagacac
    60961 ataaatatat agtataatgt acattataat acgtacattc aattatataa atatcatatc
    61021 atacagattt tattttaaaa ctatgagagg gaatctaatg aaaacatcta aaaaagagtt
    61081 atttttaaac ttcataaaaa cgcaacatga ttggatagat tcatccacat tagctaatta
    61141 tcttaatgta tcaacacgtt cgattagaaa atatgtaaat gaaattaatt ctactggtga
    61201 atttatatta tcctctaaaa aaggatataa agtaaatctc aataataact gtcaaaccaa
    61261 ggttgatagt tcagaaaata tatcacctga taacaggtta aatttaattt taaaagaact
    61321 tatagttaat agtaatggaa ttaatatatt tgatttaagt gaagaattgt ttgttagtcc
    61381 agctactatt gaaggggata tagtcaaagc taataaattt ataggaagtt ataatttaaa
    61441 gataaagcaa tcgaaatttt tattgaaact aattggaaat gagtctgcaa agcgcaaatt
    61501 aatgagctct ataatattta aagaaacggg aagtgatttt ttaagcttat ttgatgtaca
    61561 aaaaatatat caagagtata atttgaccaa actgaaagaa aatataatat atatattaaa
    61621 aaaatacaat ttgtttataa atgagtacgc tataaataac atacttcttc atttaatgat
    61681 aactatagac agaataaaaa agaataacta catagaatct gtcgaagtag taaactacat
    61741 agataataat aatgatataa gcatttcaag agatatatca aattttttag agtctgaata
    61801 caatttaact ttaactagtg cagaattata ctacttagta tttcagttaa caaacaaaac
    61861 cacagtctta aattatcatg aaatggatac taagtcattg ccaaattata tagatgaaca
    61921 ttttgttaaa ttaactaaaa aaataattaa aaatgtatat gacttatact ttatagattt
    61981 atctgatgat gaatttgttg taaaatttac tcttcatgta aaaaatttaa tcagtagggc
    62041 taaaaataat caagttttga gaaatcaaat acctcagaag ttaaaagatt cctaccctct
    62101 gatatatgat atatctgttt atatttgtaa tcaaattcaa attttagaaa acatagaaat
    62161 agatgaagat gaaatatcgt atatatctct tcatgtaggt tcattttttg atagacaaaa
    62221 attactagaa gataaaattc tctgtgcatt aattactcca aattactatg atttacaatt
    62281 caaaatagta agagacctcg agaagagatt taatgaatcc atagaaatta ttcaaatttt
    62341 ttcagatact cataatcttg attttgacaa taaggtagac atggttatta ctactttacc
    62401 aattagtgat agatgcccta taccttttgt ttatgtaaat ccttacctaa acagaaaaga
    62461 ttatgataat atccaaagta aatttattca gattaaagat agaaaaaata tacttactgt
    62521 acaaaatcat ttagaaatgt actttagtga atctttgttt atgaaaaaca tatatttaga
    62581 tagtgctaaa gattacataa aatttatggg aaatattctg tacaaaaata aatatgtcaa
    62641 acccaattat atagatgatg ttcttataag agaaaaaatg tcttcaactg catttaataa
    62701 caatgtagca attcctcata gcatgaaaat ggatgcttta aaaactggag tatgtttaat
    62761 tgttaacgat aaaccagtta aatggggtga ggaaaaagtt caaattatag ctatgatacc
    62821 tataaatgaa aaagaaaaag aaaaattcaa ttacatattt gaaagcttta ttgaaatatt
    62881 atctgagtgg aataatgtta aagaacttac taaggcagat aactacagta gttttatgaa
    62941 tagaatagct tatcttattc aaaatatcta aatccattaa tttatttcca atatatgttt
    63001 cttaagttat taacacaaaa tagataagct gtcacactaa aaagtctaaa ttaatatgtg
    63061 acagcttttt acctaatata ctttgcttta atactacata ttttttgatt gttgtatact
    63121 agttataaga ttgaatattt gtgttgttgt agctgtcata ttctcactag cagttgcttt
    63181 atccattgct tcttctattg tcatagctct atttactata gaaaaataag catctatacc
    63241 ctcttcatta catttaactg catcttctgt tgtggctcca gccaaaccta ttacttttac
    63301 cccatatttt tttgccagtt ttgcaactcc tattggagcc ttgcccatag cagtttgatt
    63361 atccaatcta ccttcaccag ttatgacaaa atctgcatct tttaactctt cctctaattt
    63421 aatttcttct aatattattt ttattccaga ttctaatttt gaatttaaaa atgctaaaaa
    63481 agcaaaacct aatcctcctg ctgctcctgc tccttctaca ttagctacat ctttacttaa
    63541 gtaattttta actactttgg aaaaatttct aagcccatta tctaactcct caattatttc
    63601 tgatgttgca cctttttgag acccatatat gtatgcagct ccatttttcc caaacagcgg
    63661 attatttaca tcacaggcta ttttaaactt acattcatct aattccttta atctattttc
    63721 tatttttata tgtcttattt catttaaaac ttttccacct aatcctacta acttgttatt
    63781 ttcatcataa aactcaaacc ctaaggcttg aagcatacct atcccagcat cattagtagc
    63841 acttccacct attccaacta taaaatttct atagccttta tttattgctt cctttattat
    63901 ttccccaaca ccataagttg tagtgtataa aggatttcta agttcagtcg gaaccaatgt
    63961 taatcctgat gcttgagcta tttctattat tgctgtactt gtatttttta ataatccata
    64021 tgttgcatcc acttttttag ctattggtcc agtaacttct atagtctctt ttttaccatt
    64081 catcccttga actaaagcat ctactgtccc ttcaccacca tcagcaagtg gcaatatctt
    64141 tacttgcgca tcttctttaa ccttcaatat cccctttttt attgcatttc ctgcctctat
    64201 tgaagataaa cttcctttca aagaatctat agaaattaat attttcatat ttatctactc
    64261 ctttttattt actctttatt ttaaatatat aattttataa gcttaattta tcttttattt
    64321 tatactctat atttcacttt gtatacaact tataccctta atattctttt atcttataaa
    64381 aaagggagtg tctcaaaatg aactttttag ttcatgagac actctttttg tataaaatta
    64441 aatatatgtt tattatttca acaatgataa ggaggattat ctctatttta agataattcc
    64501 tttttagcac tatctaatca tttttagcac tatttaacca atatagtttt aacttggttc
    64561 attaggcact ctacatttac agagttatta tctattgata tagattctaa ttctttttca
    64621 tttaggttag tccatttagc tgttttaata tttttgttaa atactacgtt agctgatttt
    64681 gtttcttctt tagaattgta aaatctaact actaatgcct cttctttttc agcctttttt
    64741 acaacactta acacaaggtc cttattagtt tccttaagta aactatatga ataatctact
    64801 tctatttctg attgattcaa tttcatagca ttatatggta ttttattata agtttgtatt
    64861 tttgttaaat actctttagc catatttgca acatttgctt ctagtgtaga tttttcatga
    64921 gtgactattg ctaagtctat ttttatatct cctatcattt gagaatctgg agtaggcaac
    64981 tttattcctg atggacgacc tgggcgtctt gccatttctt ctttacctag gaatcctaca
    65041 cttctaaata atgttatagc tattgtgtca aattttttcc ctactatttc aaactctctt
    65101 gtactgtttg taagaacagc tactccatgc tctttgtcag acaatccaac gaatgttagc
    65161 attggatata tagaatctgg tctttcactc cattcttcct gttgccaaac ttccatagca
    65221 tcatcataca cacttctctt tatatgtcca aactgattat cagacacaga aaactttgaa
    65281 gctatatttg ttggtatata agttctaacc ctacaatctc ttgcttggtt atttatattg
    65341 aatactacat ttattatagc tttatcattt ggaacattta taactatatc aaagtcaata
    65401 aatgaatctg ctctattatt ttttctagct tgtatatctt ttggtacttt taatctataa
    65461 tttatcttta tctcattatt aaatctattt ttctttatag tggaatttgc tactatatta
    65521 tcgttaaata ttaatttctc atttggaagt ggtgaaaaat catactcatc tccttcatct
    65581 cctccatttt ccatcaataa tacattttca aaagttttat ttaatttttt atcagatatc
    65641 tttaatgtcc cgttttcatt aacttgaata gtataaaagt cattatctac catgtcacat
    65701 acttcataag ctttttctaa catatgttca acttctttta tcatatacgc cttatacccc
    65761 attgcaggta ttttatcttt aaagtttatt gtatatacca taaatgaatc atagtttcca
    65821 taatgaacaa tttgacggtc tattaatcct gcatctatta cttctttatg taccacttca
    65881 aaatccaact tattattatc tttatcaaat atttcaaatg ctttcatttt agttataact
    65941 tgggcgttca ctatttcatt cctattgtaa ggcattaagt taaatgctac taacttatct
    66001 aaagccattt cacaactcat tgcatcaact attcttcttt tgtaaaatgt tattaattgg
    66061 tctacttttt cctcagctaa gaaaaatcta ttcattattt cctggtgaac tttatctgaa
    66121 caacaacatc caatgctgtc atgagcatga tttttcatta tttctttcca aattaactct
    66181 attaatccat gatgatattc aaatcctaga gaatatgcaa tagaagctag tggctccaat
    66241 atgttggtta tctttgattc tattctagca tttgctgatt ttatatccat tcttgttgag
    66301 aatatacttc tatgaaccct catatatttc ccatctaaaa attccccttt tattgtatct
    66361 atatccttat ttttttctag ctctttaaat atgttttcat atctacttaa gaaaaatttt
    66421 ctctctggat aacattcttt taatttatat ataacttcaa atatattctt ttgaattggc
    66481 atttggtcat gtccatttgg aagtattata tggtcagtag ttgcaccctt atcaagaacc
    66541 ggtaaatatt tatccattct tgttcttagc tcatcttcat tcattggtag atattttcct
    66601 attgcataac ctaatggaag tatttgaacc aaaacagaag acccatcatc actcttccaa
    66661 ttaaactctg ttttattagt tccttttctt tcagaacatc ctctccaaaa cattgagtat
    66721 tttatatcaa acccatttag tatttgcggc atttgagcac tttgaccaaa tgaatctggt
    66781 aaatatccta ttttcatata ttctccaaat tcatcacaat cttttattcc atacagtaaa
    66841 tttctaagta tggattctcc accaactacc atttcatcag tttgagtata ccaaggacct
    66901 attattagcc ttccttcttg aactaatttt tttattctct ccttacattc aggcttaact
    66961 gctaaataat cttctaatat agcagtttga ccatccatca cataatatgg atagttatga
    67021 ttattttcta acatatccat tatttcttcc atattattta caagtaatat tctagattcc
    67081 tcagttgaga agtaccattc tctatcccaa tgcatatgag gaactatgtg tacatttttt
    67141 ttcattgctt atcctccaaa acttatctga taatattttc tgtctaatta aaaatccaat
    67201 aaaaatacta ctgagtttac acaatttttt aatatttatt ttatcactat aattaaacct
    67261 ttgatttaaa tatctaataa cgtatctttt aatgtatctt tctttgattt ttttgtttcc
    67321 tagttattat taataatatt gctgatatta tagctccaag tactgccgca aagaaccata
    67381 ttgatgctat aataaatcct gacatacttc cctctaaaag cgccaatgag aatatccccg
    67441 ctccaggcac ttgaagacct atattgaaga atgctactat agacccagtt atggctgaac
    67501 cagctactaa tgatggtata acatggattg ggtcctctat cataaatggt attgcacctt
    67561 cagttattcc agccaatcct aatatccaag tttgctttcc tatttccttt tctgattctg
    67621 aaaataaatc tctgcctaaa acagtagcta ttgtaactcc aaaagctgag accatcttaa
    67681 ctgatgcaaa tattgcataa ggtataaaat ttccacttgc tattgctcct attgcaaatg
    67741 tataggctgc tttatttatt ggtccaccta agtcaaatga aaccatagct cctattattg
    67801 cacctagtag tattgcattt attccagtca tcccatttaa ccaatttata agaccattgt
    67861 taagtgctgc tacaggcttt cctattacaa ataacatcaa taaacctact accaaagaac
    67921 caactactgg atatacccaa aaacttacga atccagctaa tgtgcctttg gctggtatat
    67981 tcttctttaa aaattttact atataaccag caagtaaacc tcctaacata cctccaagaa
    68041 atccactacc tattaaatca gctgctagac ctgctgcaaa tcctggtcca agacctggtt
    68101 tttcagctag tgagtaagac atatatgctg ataatactgg aaccatcaat gtacctaaca
    68161 tccctccaga aagctttctt aattgccata accaagaacc ttcttgattg tatagttctt
    68221 gtaaaccaaa tgcttgagat gctaatactg caaatgcaag tatcatacct cctgccacaa
    68281 taagtggtat tatatgagat actcctgtaa gtattgctga ttttacatct tttttccatg
    68341 atgatttttc acaatatgat atatcagatg atttttctat ataatcacct ttaccttgtt
    68401 tttgtgctac ttctaaagct tcgtatatta tttcttttgc cctttttagt ggagctgcta
    68461 ctgacgtttt tatgtttggc aaatgttcaa atctttctgt atttttaggt gctacatctg
    68521 ttgcatatat tattgcatct gcctttttta ttatatctgg tgtatgaggg tccaccatac
    68581 cattagctcc ttgcttttct acatacacat ccacacctat ttctttgcca gctttaatta
    68641 atgcttctgc tgacatatat gtatgtgcta tacctgcagg gcatgctgtt attgctaata
    68701 caattttttt tgattcattt tgaatcctaa tctcttcttt tatttgttct ttcttttctt
    68761 ttatatctaa gttattaaat aactctttct tagtttttga atttaacaac atattcatat
    68821 aatcttcatt agacagtcta gtaactaact cagaaagtat ttgtatgtgt gtatttccac
    68881 cttcactttc tggtactgct attaaaaata ttagctctac tttattattt gagtctacgc
    68941 tttcccaatt ttctattggt gtctctaagg tcatagctgc aaatgcagct tctttaactg
    69001 acttagattt tccatgagga attgcaagcc ctctttcaaa acctgttgga gataaagttt
    69061 ctctgtacat tacagcttct aaatattcct cataagatgt taacttgcct tcatcatata
    69121 gctttcttgc taagaacttt attgcgtctt cctttgtttt tattttttgt tttaaaaaaa
    69181 caaggttttc atttgtgatt ttcttaaatt ccaaaattac gacctcctta aatcatttaa
    69241 tgttatgaat atagcataaa ataaatcatg aaaatgtttt tttgaaatta tacacacaat
    69301 ttcttcttaa aaaataagga tttgtgtatt tatacacaaa tctctatctt aaccagtatt
    69361 gttctattat tgctctcata atcatcataa ttggaacctt atctgatata ttgtacccat
    69421 ttacttgttt aattgttgaa tagcaatata aacttatatc tgcaatttgt tgcaattgat
    69481 tttcacatat atgtgttaga gctactacct tacaaccctt attaactgct gtctttgctg
    69541 cttctataac ttctttcgtt tctccactta aactaagcgc gaaaaacata tcttgttcac
    69601 ctaattttcc tatatcatga agtacttcat gtctttggct atagtaagtt atattatcat
    69661 gcccacctct aatttctttt actaatatct cacataaagg aatgttttga cctattccat
    69721 aaactataat actcctagat ttttgaatta tatctgctac tttatttatt ttttcataat
    69781 ctattagctc taatgtcttt tttatatctg attcaaaacc attttttggc tctttatcct
    69841 cattttttaa ctcttctttt aaattgtttt ttagttgaga gaaaccatca tactccattt
    69901 ttttacatag cctaactatg gtatttggga cagtaaaaaa tttatctgct aaagattgta
    69961 ttgataattt tactatttct tctttgtttt ttctcatata ctcaattatc atgtcttctg
    70021 tatctgtaaa tttatactca tatttttttg ctctttcata aaattccata gtttctcctc
    70081 catctatttt attattcata agtaaaattc aaaaatatta gctaaaattt tcgttaatat
    70141 aattataatt taatattttt aatttattaa tgcatactac tctttttatt atacataaaa
    70201 aatgtgtact tcctatattg atagagatga ttcaggtttt tattttgata catctctatc
    70261 aatatttttt tagaaaatac acattttttt caaatactta tttttaatta aaactttagg
    70321 taatctattc tttatatata attattagac ttgaaaatat ctttaaaatc aaccaattca
    70381 atattatttc tttttaacca cattttaact tccttatcac atagcattgc atgttcatat
    70441 actctctctt gaataagaga agatgatttt ataagactat aatctataaa tcctggatga
    70501 gtaaccatca atgttatatc tttatctaaa tttatatatt tttcttcaaa taatttaaca
    70561 aaagatttat ttaacttgta aaaatcattc tgaggatatt tacttggcat gctaatacat
    70621 gaatctaaat aatagggaca acttggtata ccgtattctt ttgcagcatc acacattgct
    70681 gatattgata catcttcttc tataccatgt atatcaatat actcaggcaa tttactcata
    70741 tacaacttgt aagtttcaat ttgagcacaa acttcttcat atacttcttc ataattaaaa
    70801 acctctttac ctgtcagtag ttgcgttctt cttattttgc tagaaacaaa ttttccacct
    70861 tcatctaaca aattctttat cttaatatgt tctttacaac aaggttctcc tattactaaa
    70921 ttaacatgta aaccaaaaca tacatcatca ttttttacca tttctatagc ttgtcttgaa
    70981 aaaggcatat tcaccatgat tccagcactt gtaacaatac cgttcttata agaagatatt
    71041 atccctagtg taacaccttc tgaatatcct atatcatctg ccctaactac taatttcttc
    71101 attttatgca tctgcctgct ttctcaactc atcaagttgc atttccatct catcctttac
    71161 tttaacaaca tccgttccta tgatgatttg aactgatgta ttactcaatt taattacccc
    71221 tttggctcct gtttttttaa tattatcatc attcaaaata gtggcatcct tcacttctaa
    71281 acgtaacctc gtcatacaat tattaagagt cactatattt tcataaccac cacaattttt
    71341 aattatctgc ttagccatat atgaaaaatt accatgagaa agttttaaat tcttttcttt
    71401 ttcactaact ttatcaccta tctctatctc aacttcatgt cctggtgttt gtacattatc
    71461 ttttattatt atatatttaa atgttacata atataataca aagaatacaa ctcctacagg
    71521 tataactaac cacgctttat ctccataact aaaacttaag acatagtcaa ttatacttgc
    71581 tccattaaat gaacccaagc gagcacccag taaatatagt acaactccac ctagaccaga
    71641 ataaaaagaa tgaattatat ataactttgg agatgcaaat aaaaacgaaa attctattgg
    71701 ttcagttact gttgccataa aagaagtcaa tgctccagcg gtcattgcac cttttacttc
    71761 ttgcttcttt ttatcttgtg ctgttttata tatagcataa gaaatagcag gtattgaaaa
    71821 catcataatt atgtaaaatc ctgtccagaa gaatcctgca tttgggtctc ctgccataaa
    71881 tctaggaatt tctcctctta taacttctcc tgttgatgtt gtatattcac ccatttcaaa
    71941 taatatgtaa gcatttaaaa cttgatgtaa cccagttggt attagtgcac ggttacagaa
    72001 taaaaacaag aatattccta ttgcaccagc tcctcccaac caaaaaccaa attgattcat
    72061 tgcagcttgt ggatatatcc ataataaact aaatatatat gataaaatta aagcaaccac
    72121 tggtgatagt gtaattacac atttttctcc tgcaaagaag cttaaaaatg ctggaacttt
    72181 aactttatat gttttattgt aagtccatgc tatacaagct ccaacaatta tcccaccaaa
    72241 tacacctgca tttaatgtat cattcaataa ctctaaattt gacttaaata tcatatatgc
    72301 aactacggct gcaaccatta cacttgtctt gtctttagac tttgaataag cactaactgc
    72361 tcctaataaa aataagtagt ccacatttga aaatactata ttagatatat tagatatagc
    72421 tggcacatta agcatatttg gaccaaataa taatcctaat atacctgctg ctggcattac
    72481 agctattggc accagcatag tctttcctaa aagtgacagt tgttgcatca ttttgtttaa
    72541 gaacctcttc atatccaatc ccctttctat ttcggtttaa ttttttgtga aaacgattta
    72601 ttcacatttt atattttaaa tattatattt atttaaacaa attgtcaata ttttttattc
    72661 attttatttt tatcatttag tttcatatct aaatcctttt aagtatattg ctatatctag
    72721 cctatttttt aaatttattt tttttatttt taaaatatgt ttaaccatgt atttgaaaca
    72781 acccacaaaa tagttcaaat ttatcctttt tatggtttat ataattctat tttcactata
    72841 catgtctaaa cacatttgat ataatttgtt catatcagtt caataatatt actaaagacc
    72901 tttaaggagg gataggggta tatggctaaa aataaatttt cagagatata tgaagtattg
    72961 aaagaggaaa tacttgatgg taaatataca agtaatatga tgctgcctac tgaacttcaa
    73021 cttattgaaa ggttttcatg tagcagaaac actgtacgta gagcaatttc tcaattaaac
    73081 acagaaggat atgttcaaag tataaaaggc aagggtgttg tagtgttaga aaatagttgt
    73141 tctaatgatt tttttctaaa tatgcacaat ttcaaaggtg tagaatcgat tgtagaagat
    73201 aaaaaggtta atactgctac tagtgttctc cacttcagca aaatcttaat tgataataag
    73261 ttatctaaaa agacaggttt taaagttggt agtgaagtat attaccttca cagactaaga
    73321 tatattgata acatacctaa aattctcgac attaactatt ttctatgtag tatagttaaa
    73381 gaccttgatg tttctatagc acaaggctct atttataaat atatagaaga gtgtataggt
    73441 acaaaaattg tttcatccag aaagatattt aaaattgaaa aagctacaga gcttgagtta
    73501 aaaacgctac ctctaaatga ttataattgt gttggtgtta ttaaaaatag tgtatatact
    73561 gatgatggaa agctctttga atatacagaa tcaaagcata cacctgaaac atttgtattc
    73621 atggatgtta ctcaaagata ttaaaaaaat tatgtttaat taaacataat ttttttacgt
    73681 ttagacactt tatcccatac taacctcact attctatata caattatatg tttatacaaa
    73741 taattattta ttgtatattt tagctttaat attagtttaa tacttgacaa tttgtttaaa
    73801 catattataa ttaacttata aattacagga ggtatcaatt atgaaaaatt ggtggaaaaa
    73861 agcaactgtc tatcaaatat atccaaaaag tttcaaagat agcaacaatg atggtatagg
    73921 tgatataaat ggtattatag aaaaattaga ttatctgtat tctttaggtg ttgatttatt
    73981 atggttgact cctatgtacg tttctcctca aagagataat ggatatgata tagaagatta
    74041 ttataatata gacccaaaat atgggacaat gagtgacttt gaaaaactct taaaagaagc
    74101 tcataaaaga gacataaaaa taatgatgga tatggtccta aaccatacat ctactgaaca
    74161 taaatggttt aaagaatcta aaaaaagcaa agacaatcca tatcgtgatt attatttctg
    74221 gaaagatgct aaacctgatg gttctgttcc taataactgg atatccagat ttagtggaac
    74281 tgcttggaaa tatgatgaaa ctactaacca atattattta catttatttg aagaaactca
    74341 agctgattta aatttggaaa atgaaaaggt tcgtgaagaa tgttacaaag tactagaatt
    74401 ttgggctgat aaaggtattg atggttttcg tttagatgta gtcaacctac tctccaaaac
    74461 acctggatta cctgatgacc ctataacagg gccaaaagga gatggaagaa ctcattacgc
    74521 tgatggtcct cgtatacacg aatatttaca taatatgaat caaaaagttt tcaaacctaa
    74581 aaatatagtt actgtaggtg aaatgtcatc tactacacct gaagagtgta tcaactatac
    74641 tagagaaaat cgagaagaac tatctatggt ttttagcttc catcatatga aaacagatta
    74701 taaaggaggc gcaaaatgga ctaatgaaat gttctctctg gataaattaa aaaaagcaca
    74761 atctgacttt caatataaaa tgtatgaagg aaagggatgg aatgctctat tttactctaa
    74821 tcacgaccaa cctagagctt tatctcgatt tggagatgat agattttttc gtcaagaaag
    74881 tgctaagatg ttagccataa cactatttgg tctacaaggt actacataca tatatcaagg
    74941 tgaagaaata ggtatgacaa atgcctactt tactaaaata gatgaatatg atgatgctga
    75001 aagtaagaat gcatactatc atatgattaa atctggtatt gatgaaaagg aggcattgct
    75061 tatacttcaa caaaaatcca gagataatgc ccgtactcct atgcaatggg ataatactat
    75121 ttataagggg ttttctaatc ataaaccgtg gttaaaagtt aataatgaca atattagtgt
    75181 agaaaatgag cttaatgatt ctcgttcagt attttatact tatcaaagat taatcaaata
    75241 tcgtaaacaa tatgatattt ttacagaagg tacttataga ttgttagatg aaaatcataa
    75301 aaatctattt gtttatgaaa gagagtataa aaaccaaaat cttcttgtta taagtaattt
    75361 tactcatgat aatgtagtat ataaattacc tgaaacttat ttgaataaat taaactacac
    75421 aatacttgaa accaattaca ctagagatat aattgaaaat aaaatggaaa taaaacctta
    75481 cgaaagtata atgatatatt ataaataaag ttatttatat aaaaattggt ataacaccag
    75541 ggtgttatac caattttact aaattcaaaa taacatttat agaatatcta tagattacaa
    75601 taattatttg acttctacat cattatattt ctttgaatat actttagtca tatagaaata
    75661 tataggaact acaattatca tcccacctaa tccccaaact atcttcatag gttcatcaat
    75721 acctgctttt atcagtaata atatacttat aataactgca aatattggta taattgctcc
    75781 tccaggtatt ctaaaattta catctttatc agcatacttc tttctcaata ttagtacagc
    75841 taaacatgta ggaatatatt gaataaatct agatacaaca cttatttgag ataatgttgt
    75901 gaatgaaccc gaccatgcta ttagtaaagt tcctatgaca gatactataa ttgctatata
    75961 aggagctcca tttttattag tttttcttat agacttaggc attaatcctt gttcaaccaa
    76021 agcagcagca gaccttggtg taaatatgga tgatgcaata tttatacctc caacagatac
    76081 tatagttcct attgtaatta tatacccacc tataggacct agcatcttaa tggcagcatc
    76141 tgcaacagga gtagctgacc ctgccaagcc attacccaac acccctatac ttattcccag
    76201 tataagcata tatattactg atactacaaa cattaccatt accaatgctt taggtacatt
    76261 tttcttaggg ttctccatat cttttgctgc aacagctaaa gattcaaatc ctgtaaaagc
    76321 ataaaataaa gttatagata ctgctacaaa agctgatgac gcactttgac ccttttgtat
    76381 tattacaaat ggggtaaaat tagaaccctt tataaagaat aatcctacag ctataaataa
    76441 aactattggt aataattttc ctatagtcat gatattattt aagtgcttag attgtttcat
    76501 tcccataaaa tttataatcc caagtcctac aactaatata ccaattatta tatttttaat
    76561 aagtggttct gctgcttgtg gccatacaga tgatagtgtt acagcaaaaa aatttgccat
    76621 agtagcccaa gcaatcatac taactatcca cttcataaat ccaacttcaa atccaacaaa
    76681 atctccaaat gcctcttttg cataaagata aggccctcca tcagtatcaa accaactacc
    76741 tgcttcagca aaacataaag caatagaaac agctaaaagc atacaaaaaa ctaatactaa
    76801 tatacttgct ggacctatat ctgtataagc atcaccaggt aacccgaata tacctgaccc
    76861 tattattgca ttgattccta atagtacaat actccaaaaa cctaacttaa tgcctttttc
    76921 cattgttatt ccccccaaag ccaacttaat atatttatat tttttattta gatgcttctt
    76981 taactattgc cataaatatt tttttcatat tatcataatc tctagtcatc atttctggat
    77041 gccattgtat ccctattaca aactcacttc cttccttttc tatagcttca attaaaccgt
    77101 ctttagatgt agctgaaaca atatatcctg gtgctacttt gttgacaact aagtgatgaa
    77161 aactattaac taaaacttct ttttctccta atatttcata taattttgtc ccctccttta
    77221 tctgtactgt atgtgtaggt acattagata gatgttgctg attgtgttta atataagcac
    77281 cttcaattaa agataaatct tgatacaaac tacctccttc agttacattt ataatttgtt
    77341 ctcctctaca tatacctaaa actggttttt tcatatctaa agcatgtttt aataatttca
    77401 tatcaaaact atctctcttt ggtgatattg cccccaactt attatgaggt tcttctttcc
    77461 atatgagtgg atttacatct tgtcccccag atagtataag cgcatctata ttagatacct
    77521 gctcctttat aatctcatca tcatatacaa tcggtacaat atatggtata gctttacaca
    77581 taactactga ttgtatataa tcattattta cataagccct ttcatagcca ggaaacattc
    77641 ctccttcatc aattagtaaa ttacctgata ttcctattat tggatatttc tttttaacca
    77701 atttcttcac cccttaactt atttgtgaac aataaaaaat gctacttctc ttaaagagca
    77761 agtagcatac caagatttta tttatttgaa cattataatt cattttagaa atactttttt
    77821 tgaatacaag taatataaat aactttattt acttatattt tattttaatc ctgtttagtt
    77881 tgactttttt aaattgtttt aagtacaact aataggtaaa ataggcattt agattttcct
    77941 ttttatcaac ctattaaata ctgtttaata tattttttcc ccttctattt aattcacttc
    78001 cctttctacc agattcacat attatcaaat ccagctcttt taacatatta agtattcccc
    78061 ttacctcacc ttctgttata ctgtagccta attcatttat tgaattaaca ataccatttc
    78121 tacctatatt tttattaaga ttattggcat tttttaaaca ctccattact aactttactt
    78181 tctctataga tgttctatcc tttaatatgc ttatttcttt actaaaatct tcagttatat
    78241 ttaataagtt atgaggtaaa tcatttatta aaataacatc ctcagaactc ataatgttaa
    78301 tatacatagc agtatttttt aattctctta tattacctgg ccattcatat gcattaataa
    78361 tgtcttgaac accttgacta attgctctct tccttttcat aaaatgcttt aacataactt
    78421 ctatatcttc ttttcgctct cttaaaggtg gtatatttat gggcaataca tttatcctat
    78481 agtataaatc tgctctaaat ctatctcctt ttatcatttc taataaattt ttatttgtag
    78541 ccgcaattac tctaacatct atatctatta cattttctcc tccaaccctc attacttgat
    78601 tctcttgtaa tactctaagt aatttgcttt gtaagtatat aggcatgtct cctatttcat
    78661 ccaaaaatat agttccattg ttagcctgtt caaataatcc ttttttacct ccttttaaag
    78721 ctcctgtaaa agcaccttct tcatatccaa aaagttcact ttcaagtaaa ttttctggca
    78781 tagctgcaca gtttatcgct ataaatgact gactatgtct tggtgatgca ttatgaatag
    78841 actgagccat aagttctttt cctgttccac tttctcccgt tataagaatt gtataatcag
    78901 attcagctat tttcatacct aatttcttag ttctttccat cttcgttgaa actgttttta
    78961 tatcatcaaa agtatatcta gcaacttgtc ccttttctct aagcttcttt gataggtttt
    79021 gctccaattt tcttatataa gttatttctt gaatacaaaa ataataccca gtaacccttc
    79081 caaaactctc tatattatac ttatttacgt ttaagtactt attattaaat tttataactt
    79141 catcatgtgc cttactcaaa ctaaaaatct ttttaatatt ctcattctct aattcatcta
    79201 tatttttccc tataatatta ctttgaatat ctagtatatc ccttaaacta ttattgcaaa
    79261 taattatgtt tcccttatct gataccattg ccatacctaa gtttgataaa tttattatag
    79321 aatttaattc atctgctttt atagtaagtt ctttgtattt agtatttatt cctgaatata
    79381 aactaattat ttcatctgta tacttaatta gcctctcagt aatttcttta tcatccagtt
    79441 tgagttttgc tattatttga ataaacgttg aactatcaat atacctatgg cctaaatcaa
    79501 taacttcttc tatatatttt ggaactaaac ttgactctcc tggcgttata gctatcttaa
    79561 tatttctata ttcttcattg ggattgtatg gtataaaatt caaatggttt attcctatat
    79621 tgtataaatt agatattgtt tccaatacag tatgcttatt atcgtttact actaatacat
    79681 ctatttcttc tggcaatgaa aataacttat atatatcctt ttgctttatg ctcctattta
    79741 tagttattat ctttgagaca tcttctacat atttttttat ttttaatact ctatcatcta
    79801 tcattaccaa tattatgtca tcttttatta attccttctc tgttatttta tttaaataat
    79861 aattttttat cattacttta tctttaaata tcatttctag atttttattt aagaaacatt
    79921 ctaatttaga caacccatca gttactactg ctattgtttt catttgatta ctccttttaa
    79981 aatatactct actcttttat aatatacatc tgattttcac tttaatagca caaaaaattg
    80041 tacatttagt atactaacat attcctttat tagttttatg tccctaaata tcatagttgc
    80101 aatatctatc atatttctta aacttctata aagcaaaaat tgtgccaaat taataatttt
    80161 cttaatttta ttctaaagtt cctcaatagt atttacagac ttagcactta tagcttataa
    80221 gtctttatat tattaatcta tttttatagg ttaattgtac aaatcatata tcacttttac
    80281 ctattaaatg cattataaaa aagatggaat aacgattcgt cactccacct tttttgtaat
    80341 aaaaaattgt atatataaac actatttact actcttctaa gtacaaacag tatctacata
    80401 ctataacctt tcaccattag attctattac ttgtttatac cagtcaaaac tctttttctt
    80461 aatcctagac aagtctccac ttccatcatc atacttatcc acgtatataa acccatatct
    80521 cttggtcatc tcaccagtag atgcacttac taaatctata catccccatg gagtatatcc
    80581 aaataaatca acaccatctt ctacagcttc cttcatttgc tctatatgtg cttttaaata
    80641 ctctatacga tagtcatcat ttatcactcc attagattct tttttatcat aagctcctaa
    80701 accattttca actaccatca taggtattct atatctatca taaatttcat ttagtgcata
    80761 tctaagccct tcagggtcta tttgccatcc ccattcacta gacttaagat atggattttt
    80821 cactccacct aatatgttgc cacttgtatt atcttcttta gaatcactac ttacacatgt
    80881 agacatataa taactaaatg tataaaaatc tacacaacct tcttttaaaa tttctaaatc
    80941 tcctttttcc atttttattt caatattatt ttctccaaaa tatctattca tataagttgg
    81001 atattcgcca cgcacttgta catctccaca gaaataattc attactctac tatctctttg
    81061 agttttaact gcatcatctg gattacaagt ataaggatac attgttgcaa atatttgcat
    81121 acatccaact tgataatttg aatctatttc atgagctaat ttaacagcct tagcacttgc
    81181 tacaaattga tgatgtaacc cttgaaaacg aagttgaggt atatctactt ggtttataaa
    81241 atctgtagtc ccttcattta atattccttg tgataagtag cctcccatag gcattgtagc
    81301 tgaatttatt tcattaaatg tcagccaata ttttactttt cctttatatc ttttaaatat
    81361 tgtttcacag taattcatat acaagtctat tacctctctt gaaacccatc cattgtattt
    81421 ctctgttatt gcaaatggta tttcatagtg agatattgtt attaatggtt ctatattata
    81481 ttttaaacat tcatctatca cattttcata aaatttaagt cctgcttcat ttggttcttt
    81541 ctccattcca gttggaaata ttctagtcca tgctattgaa aatctaaata ccttaaatcc
    81601 catttctgca aataaagcta tatcttcttt gtatctgtga taaaaatcta ttgcttcatg
    81661 acttggatag aatgttcctt tttctataac tctcgttatt cttttactta ctttttgaga
    81721 acccccagta cacatatctg aacaagaagg acctttccca tctaaattcc atgctccttc
    81781 acattgattt gctgctgttg ctccacccca taaaaaatct tttctaagta ccattactct
    81841 acctccaata atttatttat agtaaattta ttttaaaata aaaatacata tatctaattt
    81901 ttaattaata aaactctctt ttaagctaaa acagttatca attcctgact attatttaca
    81961 tgcttttgtg tattttctat aatatccaca taatcagaat aattagtaac aactactggt
    82021 gtttctaagc aatatccttc ttttgatatg ctttctatat caaaagttat taatgtctga
    82081 ccttttttaa tcttatcccc ttgattaaca aaagatttga aatgtttacc ttccaactga
    82141 atagtattta accctatatg tatcaatagt tcacaaccat tatcagatat aattcctatt
    82201 gcatgttttg ttggaaataa agtcattata gtcccatcaa atggtgccac tacttttcct
    82261 tctttaggtg ttattgctac accttttccc aatatacctg ttgaaaacgc tgcatcttgt
    82321 atctgctcca aagcctttac ttcacctttt attgggctat atactacttc tcttttgttt
    82381 ttttctacaa cgccttgccc attattatct ttagaaattt ctactataga atcatctttc
    82441 caaaaaaata atgttaaaac aaatcctact acaatagcta ctattattgc tattatagtt
    82501 gcataaacac ctttcatatc tccagttgtt ggatttatat aattaggtat accaaatatt
    82561 ccaagtccac ccattacata actttttaca ttcattatcc ccattacagc tcctgccaca
    82621 gcaccaccta cacaactata tatgaatggt gtttttcttg gtaaagttat tccatatatt
    82681 gcaggctcta ttacaccaca tatccctgaa ataactgcag gtatacacag ctcttttatc
    82741 ttcttatctt ttaatttaaa gtacattgct gctactactg atgtttgtgc aaaagatggt
    82801 acaaatgctc ccactaatat tgtgtcaaac cccatagtca taaggtttga catagctatt
    82861 ggtactaatc cccaatgtag accaaatatt acaagcactt gccacaataa accagttaat
    82921 acaccacata aaattggtga aaagttaaat aaagctaaaa atccatttcc aactatatta
    82981 gaagcatagg tagctatagg ccctataacc ataaatccca atggtaaaga aactaataaa
    83041 actgccattg gtacaaagaa attctttact acatctggta ttattttagc aaacactttc
    83101 tccaacttag ctgctaataa tactattata attactggta ctactgttga agtgtagttc
    83161 attgctatta ctggtaatcc taagaaagtt atatatactg gtgattcaaa tattgttcca
    83221 gtaaatagat tgtataaagg ttgacctata gatgctagag tatctaattg aatacctgaa
    83281 tagcataaaa ctgcacctat aagcattcca ataaatggtt ttaatttgaa tttcttagca
    83341 gctgtatatc caagaattat tggcatatac tggaacattg catctccgat tgcatttaac
    83401 ataatatatg caccatcagt ttctccatac aaacccaatg ctgtaaatac tgcattaaat
    83461 ccttttatca taccagcagc acacagaact cctaatattg gttgaaaaac tcctgatatt
    83521 atgtctataa acttattaag taatcctttt ggcgcatctg aatctgaatt atctattgta
    83581 tctcctccta atccagccaa atcgcacaca acttcataaa catctggaac atgattacca
    83641 ataactactt ggtattgacc tgcacttttc attacagtaa ctataccatc catttttttt
    83701 agcacatcat catttgctat tgattcatct tttaatttaa aacgtagcct cgttatacag
    83761 tgagataaac tgctaatatt atccttccct cctacattct caatgatttc ttttgatagt
    83821 tgttcatatc ttctcatttt ttctcctcca ttttcttttt gaaatatgaa ggtttggcca
    83881 acttaatgtc accacccaat atatataaac ctaattatta ggatttatat ctgacttaat
    83941 acttttactt accactcttt caacgtgaat agttaagtat aatttttcct catctgttaa
    84001 atcgtagttg tattttttat gtataaattc atccaacttt tctatgcatt tataagcatt
    84061 tttatattta acttttatta catttagtaa atcatcttca ttattttcat gtaaattatt
    84121 actaacaatt cgttctgcaa aatactttaa gtgagtaata aatctatgat aataaactga
    84181 atcttcatca aatactattc tgtaatggta tttaaccata tttgaaattt cttgtattat
    84241 ttgtgtaatc tcatatatag tttttatact ttgatccatt tgtgcattaa ctatatgcag
    84301 tgctataaat ccagcttcat cttctgatag tctaatttca aatttttttt ctatataatc
    84361 caatgcttct aaccctattt taaattcact cttataaaat ctttttatat cccaaagtaa
    84421 tacatttttt acacttactc cttcacgagc tctttctatt gcagtataca tatggtctgt
    84481 taaagaaata taaatactat catttaatct tttccctagt ttttctttag catataaaat
    84541 tatttcatct gataattcca tatatcttat aggaatatct gctattagtt ctttaaattt
    84601 atcagatata tttgggtctg aaagtttgaa tatcttatca attttatcct ttgatatatg
    84661 ctctcctgta cgttttttat aagctaaacc tctccccata actactattt ccttatgatt
    84721 ttcatcagtt gtaataatta cattattatt gagtattttt tcaataatca ttgtgatgcc
    84781 ccctttatta gcattaagtt aaaataaatc ttttttaatt atttagaata tttaaaatgt
    84841 aatttattac ataaaaaaaa acctatttat tacacattaa atagactccc atgagtcctg
    84901 agtaataaat aggtttagct tgtatttaaa caatcactat ccgtttgtat tttattttaa
    84961 ttattattta ttatatgtta gcaaatttat tttttagtgt caactttttc tcaatatttt
    85021 aattctaaat aaattatata aattgcatct gcaaagtact atttttataa ataaacaaaa
    85081 taaaaaaggt attacttgct ttaagtaata cccatttatt tttaatttaa gtggtttttc
    85141 ttaatctcat caagtagtcc atcttctaaa taaatttcta atgcacatcc taccattgcc
    85201 tttactgctt tgtgaagttt atcataagct tcctcagaat ttgcataatt tagaaattct
    85261 ttttcatgaa catataccat tggacttata tctaaggcta tttctgtata catagtaggg
    85321 caaacttgac ttacattacc tatatctgta gaacctactg gaccatcttt accttctaat
    85381 atatctgtta tacctgactc aatcaaatta ttctttgtta tcttttgaag tactttgtta
    85441 tttattatgt tgtcaaaaga attttcaaag tatctataag aaagcttagc tcctgtcatt
    85501 aactctgcac cttttgcaca gtttataact tttttagtca cttcatctaa ataacttctt
    85561 tcagcagctc ttacaaaaaa cttacaagct gctttttctg gaactatatt tggagcctct
    85621 cctccatttg aaactattcc atgtattcta acatctgatt ttacatgttg tcttagtgca
    85681 tttatcccag caaaagtaag ttgtactgca tctagtgcat taactcccat atgagggtga
    85741 ctagctgcat gtgctgatac cccttcaaaa ctaaactcta atgaatctat tgccaaagcc
    85801 ttacagttta tattattaaa agcttctata tgcatttgat aacttacatc aacatcatca
    85861 aaagctcctg ccttaactaa atcacatttt cctcctgttg tttcttcagc tggtgttcct
    85921 attagtacaa tttttccttt aaaattttct tttaacttac ttaatactat acaagctcct
    85981 agtgtagatg ctgcaatcca gttatgccca caagcatgag ctggttcttt attgtctcca
    86041 tatccaggaa gtgcatcata ctcagctaaa aatgctatgg taggtccatc attatctcct
    86101 aattcagctc taaaagcagt ctccatatta caatatggat aaactgtatc aaatccatat
    86161 tccttcattt tctctactaa gtattttgat gatatgtatt cttcttcccc taattctgga
    86221 ttgttaaata taaaattaca aacttcttca atttcttttc caagttcatt ctctatctca
    86281 taagctctct tctttatact ctctatcata acttacctcc cactagaatc ctagatataa
    86341 tcctattgtc aaaaatacca ttacaagaat tgttaatact accattaaag gaattacgaa
    86401 tctaacccac tttgaccaag gaatattggc tactgctagt gctcccatta aaacacctga
    86461 tgtaggtgtt attaagttag ttacacctat accaaattga taagctgtaa ctatcatttg
    86521 tcttgataca tctactaagt cgccaagtgg tgcaagtaca ggtattgtaa gtgatgcaag
    86581 ccctgatgct gatggtatta aaaatgctat taatccttct attaagaaag ttaaatttat
    86641 aaatatagtt tttggtaatc catttaataa atttgctgca gaatttaaaa ttgtatctat
    86701 tataaatcca ttttctgcta ttattacgat tccacgtgca aatgctatac ataaccctgc
    86761 tgtaattaaa tctcctgctc cacttataaa tgaattaact atctcatctt gtttaagccc
    86821 tgatgctatt cctgatatta tacctatagc tgtaaatatc attgcaattt cagttatgta
    86881 ccactctagt cttaaaactc catatatcat aatcgccata cctattgtga aaatggctat
    86941 taccatggct tctctttttg taaattcctt tatatttgta tcactattaa ccattgattc
    87001 ttgatttagt gatatatcgt gtactaaaga ttttttaggg tcttttttaa ctttattggc
    87061 atacatcata acaaatccta tagatatagc catatatatt ataaacataa caactctaaa
    87121 ctctattcca gaacctggta ctatttgtga taatgcttgt gctattccta cagagaaagg
    87181 attcgtagta gctgctccaa atccagctgt tgctcctata aatactgtgg ccactgctgt
    87241 caatgaatca tatcccatac tggtcataag tggaataaat atcatataaa aaggtagtgt
    87301 ctcttcactc attccaaacg tcgtcccacc tagtccaaat agaatcattg aaatcggtat
    87361 tattaaaaat tgaaacttct tcattttatt tacagtatga gctataacag cttctatagc
    87421 ccctgtttta ttaactatcc caaaagctcc tccaactatt aaaacaaatc caactacttc
    87481 agctgcatct ataaatccgt ttataggtgc tgtaaataca tcagtaattc cttgtggatt
    87541 tgatggtgct ttttcataag ttccagctac aacaactgac cttccgtcta tatctactct
    87601 ttcaaaattt ccacttggca ctatccaagt aagaattgcc attaacacta ttagcgaaaa
    87661 tattattgta agtgtctgtg gcatagtaaa ctttttcttt tttaaactgc tcatttttaa
    87721 tctccccact ttttaaatta aatattttat tattgcatcc ctttatccta ttttgtatag
    87781 atgtaaaaaa gctcaacatg gatacatgtt gagctaaatg tgctaaatac aacatacctg
    87841 catcttccct ttatcttgtt taagatagct ctccatcaaa attcgggata attttgatga
    87901 cagtactgta cctattaaat acagtcccag cactagcttt ggacactagc acttcggcac
    87961 ttactccttt tatattgcct cattggtttc caacctcttc aatattaatc ttagtaaatg
    88021 caacctctac ctcaatctgt tcgttagatg aggtaattct tattaatttt tattgattca
    88081 aagtaattgt agcataatat gtcgagattg taaatatttt cagtataata attcttactt
    88141 tatgatgtca ttccattttt cacaaataat tttttctcca tataatttaa atactgtagt
    88201 atattttaaa tacacacaaa ctttccacaa atttttaatt attataatac ctttataata
    88261 aaaaataaaa gccatgtaaa cttatcaatt tacacagctt tatatacatt aatctactcc
    88321 aagtacagct ttaagctttg atgctattgt aataactcgt ggaccaaata taacttgaac
    88381 tgagtttttc tttttaacaa ctccacttgc acccaattca tttacccaga aaccatcttc
    88441 atagaatcca tcaattgaat ttagctctac cctaagtcta gttgcacagt ttgtaacatt
    88501 ttttatatta ttacttcctc ctaaaccttc tattatagaa tgtacaagct ttgtatcttt
    88561 atcatctact tcctcttcta ctgcattgtt gtatgctgtt ttaccagcat ctacagattg
    88621 tctttctcta tattctttct tactataaag cttaacttct tctgaacttc ttcctggtgt
    88681 ttttatatca aacttcttaa ttgcccatgt aaatattata taagtaacta taaaaaatat
    88741 tggtatcaaa aataataatg gtaacgcatc cactttttgt ggttgtaata aattaggaaa
    88801 catatttcta aatgattctc ccattataga aacattaaac atttctgtaa atacatacgt
    88861 caatcctgcc agtggtacat atgctacaaa atacaataat ggtgcaacaa ataggaatgt
    88921 atactctatt ggttccgtta cccctaccaa catggctgtt actattgctg gtatcaatat
    88981 acttattgct tttttcttat tagcattatc agccaactta tacatagcta aagctgctgc
    89041 tggtaatatt gcaaaatgta ttaataaacg acctgttgtg aagttacgag ttatataaga
    89101 tagtgtatct gggtctccca tttgagctaa tcttatatta ttaacaccct cgtaaattgc
    89161 tccacctact tccattgttc cacctactct tgtatattct atagggaatg caattaagtg
    89221 atgtatacca aatggtaata atgctttatc cattgctcca aaagtaaatg ttcctaataa
    89281 tccactagaa cctatccaat taccaagttt agataatgcc aaccctactg gtggccatat
    89341 aaagtacatt gctgtaccca atactattga tgctataaac atcataatca ttgaaaatct
    89401 tggacctgag aaaaaagata atgcactagg aagttctatg tcaacaaatt tgttatgtac
    89461 tgcactagct acaaatccag ctattatagc tccaaatata ctacaatcat atgaaaagat
    89521 tcctaagaaa gaaccatata aagaacttcg actatatgct tctgcctctc ctaatccaga
    89581 tgccataaac gcttctgctg taactgtatc tgaatttata ccatttgatg ctaacaatgt
    89641 acttataact gtgtgcattc ctataaataa aacaattcct cctaatgcac cccatccttt
    89701 ttccttttta gataatccaa aagctatacc tgtaacaaag aatattggta agtatctcat
    89761 taccataaat cctaaatcgt ttattacttt aaagaataca tttataaatg acccttcttt
    89821 tattagtccg ctaagcccta atgcagaaac gttttccata tttgcaaaag ctgaccctaa
    89881 tcctataaat actcctgcta caacaagtaa tataacaggt atcatcattg ctccagaaag
    89941 tacttgtaat ttatccttca tagtattatt tcctccattt ttattgaaat gccaggctat
    90001 ataatgcata tatatatact tctattgctt tgtataatgt atctatactt atattttcat
    90061 ttgcctgatg tgaatttgga ttatctccct ctattgtggg tccaaatgca actccatttt
    90121 ttaacactct tgcataagat gcagctcctt ttgtaaaaag ttcggcttct tttccaaaac
    90181 cttgtttata tgcacttgat aatttattta ttaattcact atctggtttt acatacagta
    90241 attttaaatc cttatatata tcaactatta aattttcttt tttcccaatt tcattaattc
    90301 tattagttat aaactcccaa cttataccct taggatatct aaagtctatt ttcatattca
    90361 attcattttt ctctaagaag atactcatta tacatattgt agaaactccc atatctacat
    90421 cttctttata tatccctaat ttttttccat gattatcatc tgtaaagtat gaatttaaaa
    90481 tatcccttat tataacgcct ttatcattta gctttttaat tttctctaaa tcttttgcta
    90541 aactaaatgc acagttatat gacctgtgtg gatttctcga taaagccctt tctcctgtat
    90601 atcttactaa tactttacct tcttctagtt cttctatctc tgtataataa gctaatgatt
    90661 ctactaaatc tttcttatca tcagttttaa aaacagcctc aattttgtca catacaaatc
    90721 catcttcttt gtttgacttt atatcaacta aattgtgatt tctaaattta tctttatcta
    90781 ttttctttct tagattgaag tataaaatac cattttctcc atttactatt gggaagtttc
    90841 catctggaga aaatgcaaat tttggctgtt cattgacact aaagtaatgc tccatacatt
    90901 cccaagtcgt ctcttcagct ccacccacta tcaatctaat ctttctcttc ggcttttcat
    90961 taagttctct taagaaaagt aatgcatata aaatccctat caaaggtcct ttgttatcat
    91021 taactcctct accataaaga tagttatctt tttgacatac tttaaaaggt ttactcttcc
    91081 aaagttcttt attatatatt ggcaccacat ctatatgatt aagcacccct actacttctt
    91141 ctccttctcc atattctata tgaattgcat atccatcaaa gtcttttaca acaaaatctt
    91201 tgtcttttgc tatttgaata agcttatcga aggcatttct tatttctatc ccaaatggtt
    91261 gatttatatc tgttgtactt tcatctctaa ttgaaggtat ttcaactaaa cttctaatat
    91321 cctttatgat attttcttga ttggatttta aataatcaat aattagttct ttgtttacta
    91381 tcatcttaat tatttatcac ccctttatat taattttaca aagcatttca gttcatatct
    91441 acattataaa ttttgaatat tattttttca atatttcaaa tacttctcta aattaccata
    91501 atgatacggt aaacaatcaa cagattatga caaaatcata ctatacctat tactaatatt
    91561 ttaacttatc tattacgtct tttttaatgt aattttattc caaaaataga tataaaaaga
    91621 tgtagcctta gctacatctt tttatatcta ttcaacttcc attattatgc tattaatatc
    91681 tacatttcca ggttctatcc tatcttttac tgttctctta acagaatcag catcatccat
    91741 tataactaca ggagttatta tatttaaatc atttgacgtt ataaaatcta aatctacttc
    91801 cattattaaa tctttagctt ttaccttatc tcctgccttt accttaacat caaacggctt
    91861 tccttctagt gacattgtct ctaaacctac atgtattaat atatttgtat tatcattact
    91921 cttaatcatt attgcatgct ttgtatcaaa tacattgact atttcaccat caacaggaga
    91981 atataactta ccttcatttg gtattattgc tactccatct cccatcatct tttgggcaaa
    92041 aactgcatct ggaacatctt ctaagttcac taaatttccc ttaaaagggc tatatatttt
    92101 ctcaatctta ttttcttttt tcttaaatat attaaacata acacactctc catattataa
    92161 aattttatga taatattttt cttaaagctt ttgctacacc atcatttaca ttagtatcag
    92221 ttacaaaatc tgccatagat tttacttcat ctgtagcatt tcccatagca ataccaagac
    92281 ctgcaaattt aatcatggat atatcatttt cattatcacc tatacaaata acttctttgc
    92341 tatctatacc taatatatca caaaattttt taactgcaat accttttgaa gtacctttac
    92401 tcataacttc aaaatttatc tttccagaac ttactacttc taaatcttct tgttttttaa
    92461 attcttcctt tgcttctctc aaagaatcta cgttttctga gaaaagtata cattttaaaa
    92521 tttcattatc agctttttct aataaagttt cacaacttgc attttctatt atttcaattc
    92581 tgtcttcttc tttattttta ctatttatta atctatatgg atgttcttca cctatttcat
    92641 tgttggatat aactatttta cagcctttaa aatgtttgtt taaattatac ttttcaccta
    92701 ttgtatagat tttctttata gcttctttgc tcaaaacctt cttatactca tatcccatta
    92761 atttaaaata tgtcccatta gttgatataa tatatatatc atcccctaaa acacttgtaa
    92821 aatatttcat agcattataa ggtcttcccg taactaaggc taccttgata cccttttcca
    92881 tagcttcttt tagtgcttta atattttctt ctgatacttc aaatcctttc cccatcaaag
    92941 taccatccat atcagtacaa attaatttat atcgcatttg tatcacatcc tagtaagatt
    93001 tttctaatat ttcaacaagg tcttctttct ttccaaaagg taaaaatcct aaaactggac
    93061 agcttgttat ttgttctaat tgttcctttg ttacattaaa ctcagacatt tttgtcttaa
    93121 gtcccactct ctttaaaaaa ctttctattt catttcctaa agttttagct gcttcatcat
    93181 cttccacttt ttctaattct tggtttagca ttctcgctac tttggcaaat ttctctatat
    93241 tatccttata gaacttttct gcaaattttg ggaacactat agccaaagcc tcaccatgag
    93301 gaatatgtgt aactcctcct attatttcac ttagtggatg tggtgctgct gctccagcat
    93361 ttgccagtga acttcctcct aatgtatctg ctactgctaa ctttgttctg tattctatat
    93421 tatttttatc ttccattact ttaggtagat agttaatgac taattccata gatttttcag
    93481 acattatctc tgtaaagtca ttagcatttg gatttatata actttcaaat gcatgagtaa
    93541 aagcatcaaa tgctgttgat gcagtaattc tctctggcag agttaacata agctctgggt
    93601 caactataca ttcttttgag aaacaatttt gatgaaatat tgtatttttc tcgcttcctc
    93661 tcgatattac tgctgcttgt gtaacttggc ttcctgttcc agaagtagtt gatacagcta
    93721 ttaatggtaa ttctttttca cttaccttat cgtatatttt aaatggattt gtatatgtac
    93781 taaacatata atcccaatct attttttcta aaccaaaagt caatgctaat acttttgcag
    93841 tatctatact tgaacctcct ccaacagcta aaacaacatc tacagattct tttttagcta
    93901 attcgaaccc ttcatttatt aattctacag ttgggtttgg ctctactcta tcaaagtgta
    93961 caacttctat acctttttct attaaattca atgtaactct tttatataac ttgtctaatg
    94021 gctctacatt tggagtagta actaacaaac atttctttcc atattttcct attattctag
    94081 gtagttcact taaagttcct tgtccaaaat ttattcttga tggttgataa aagttaatca
    94141 tatttttcct cccttaaatt attgacttca tattcaaatt atacatatca taggattttt
    94201 aaggcaatac cttcactgtt aactcttatt tactaaagct tatggcaatt attagacaat
    94261 aaatgtttta ttattaccat atcattatgt aaattttatt aagtacccat gttataattt
    94321 tataatcaat cttattgtat aattgactta ataataaaaa tagagtatat acactttttt
    94381 atgacaaata gcttaaagga gaattaaatt atgaaatatt tgatagacag tgctaatctt
    94441 gatgaaattc aaaagtgttt aaagtatgga tttaagggaa taacagctaa tccatctatg
    94501 tatcttaaag agaaggtaaa cttccatgaa tttattgaga catgtactaa tttaaatcca
    94561 gaaatattaa ctgctgaagt cattggaaat aatttatacg aattaattaa ttcatgtgat
    94621 aagatattaa atataaataa aaacactata ataaaaataa atttctctga agttggctta
    94681 gaacttataa acatattaaa tagtaaaggt gtaaaaactg catgtacctt gattttcaat
    94741 gtaaatcaag catcattagc tataaatgca ggtgctgatt acctattccc ttttataggt
    94801 agaaatgatg aaaatgggaa tgatggtata aaaaacctta cagaaatatg taaccttata
    94861 tcaataaatg gatataatac taaagttgtt gcagcttcta ttaaaaatgt attccactta
    94921 actcaagcat ctctttgtgg atgtgattat gcagctgtaa catatgattt atttaaaaaa
    94981 gcttctttta accagcttac agtagatggt gccaatactt ttgaaagaga ttggtccaag
    95041 gttaataaat agtaactaag atttaggagg gtttgcattg aacaaaagat tattagatat
    95101 tgctgaatta ttactcaaca gctcagacta tattactgta gatactattg ccgaagaatt
    95161 aaaagttagt aataaaacta ttcgtaatga ccttgttatt ttagatgaat ggcttttaga
    95221 gtttaattta tccctagata aaaaaactgg ttcaggggtt attattctag gtaatgaaga
    95281 tataaaactt aaagttatta gagatatcaa tgataaatca aattgtatat atgcatactc
    95341 tcctgaagat agaaaaaggt atattctaag taaattattt attaaaaatt ctaagtttag
    95401 gattcgtgat atttgcaatg aactacatgt tagtagagct actgttcata aagacttggt
    95461 agttattcaa aattttttgc aaaactttaa agtgactcta gttagaaaaa ccaataatgg
    95521 agtatattta gagggaaaag agaaagatat tcgaaaagca gtttttgaac ttgctactgt
    95581 taataaaagt tatactgaac ttaaagaaat attattctcg aactctaatg aatgcaaaga
    95641 taccccatca acaaaaatat ttaaggagct atttaactat gattttgaga aattatctca
    95701 aatcactcta cacaccttac aagtagaaaa aagtaacctt agtgatgagt attatataaa
    95761 cttcttaata catatagcta tatgtattaa gagaatttca attaaaagat atattaactt
    95821 atctgaaggt ttttttagag aattattaga acatgaatac tttgaaaaat caaaaatttt
    95881 atgtgctaac ctaagtgaag cttttgacgt agaatttatt gatgaagagg tctgttatat
    95941 acttcttcat atagaaggat tacttaaatc aataaagaaa actactactc ttgaacctct
    96001 taaaaatgaa gaaattacag agtataatct atctgaagca atagctgttc attggggaag
    96061 tatactaaat ttaaacttaa aggatgattt aatattaata aagtctcttg ctaatcacct
    96121 taaatcagtt ctacacagaa taaactatgg atttactatt acaaatccca tattaaatga
    96181 tataaagaga acatttcctt atacttataa ggctgctaaa gagtctaata ctgttatcaa
    96241 acagttgatg aattatgaag tcaatgatga cgaaatagga tatcttgctt tatatttaat
    96301 atcagcaata gatagaagca aatctcccct aaatactatt ttaatatgtc actgtagtga
    96361 tggtgtatct aatttattag tccaaaagtt aagttttgaa tttaatcaga ttaatatagt
    96421 taaatctata cctctatctt ctatttcatt tacgaacttt gatgatgtgg acttaatact
    96481 aaccactgct cctgtagact ttgaacataa tgctgaactg ataaatataa atgctctttt
    96541 aagtaagaat gatatttcca gacttagtac aattataaaa aaactatatt ctgaaaaaaa
    96601 taaaatatta tcttataaat aaacaaaaat aggcttgtct caacatagag ataaacctat
    96661 ttttcattgt ccaaatgata aaaatatatt tgatttcata gaaaaagtgc ctcatgaact
    96721 aaaaaattca ttttgagaca ccttcatttt ttatatttaa tctttttatt taagctttta
    96781 tattttttaa acttttatat tttttaaact tttatattta aagtaaattt tattattttt
    96841 attgagcgca agcattattt atattattaa tttcttcagt attcttacca aactttgtag
    96901 ttacaaatcc tattgttttt attatgagta ataaggatat caatgaatat atagatatca
    96961 taaaattctt acttattatt ccagatgcta ctattataaa tccatctagc ataaataata
    97021 taactggcaa cttcagaaac ttaattacct tattaataag cattgcaact aaatcagttc
    97081 caccagtact acagcccctt attattgcta tccctatagc agttcctacc aataacccac
    97141 ctatcactcc tgctactaat agattgtcag ttatgtgagt ttgtggtatt acttttaaga
    97201 ataatggacc cataagagtt atatataatg tttttattcc aaaacctttc cctaaaaata
    97261 ataatcccat tactaaaagt ggcatagata ttcctaatga tatattctca acaggcattg
    97321 ataagaatgt gctaagtacg actgataatc ctgttatccc tcctggagct aatgtatgtt
    97381 ctgcaaagaa aaaattaact gctaatgcca ttaaaaatgc tgatattgtt atcagtaaat
    97441 aatcttttat catttctttt ttcatttaat aacctcctat gattatattg tttcagtata
    97501 aaaaatcaat taaattagtc tagcttcctg tagtttttca taaaattaat gcttccttaa
    97561 aacattaaga aagcatctct tttatcatag tttattatct tattctaaac caaactttgt
    97621 agctgcttca tctatagctt ttctacaatt cttaacacct gctgttatac catctttatc
    97681 cttgaatatt gctgaagata atattacaac gtctggatta cattctatta atggctccat
    97741 attgtctgct cttagtccac catctattgc taattcacac ttaggattct tttcgtctat
    97801 catttttcta gctcttttta ctaaatcaac agcactcttt ctccatcccc agttatcttt
    97861 tccatcagtt tcatcaacac catgaacgac tatttgcaat ctatctatat catatatagc
    97921 ttcatcaaca aaacatagtg gtgtgtaaca tccaattgtt aatcctactt tcataccaaa
    97981 ttctctacag taatttatta tgtatgcaag aggagcgcct aaaaaatgtt ctgctggtat
    98041 tatcaacaag ttacatcctg ctgctgctat tttttctata aataatctat cacaatctct
    98101 tgtgtatata tggcattcta ttggtttatc tgtcactggt cttattgctt ctattatttg
    98161 atgaccaccc ataagttgca tattttttaa gtcatgcata tctgctgcat ctgaatgtac
    98221 gtagtctaca cctgcatcca ttgcttcttt aactacggct gatatatgac cgtaatttac
    98281 atgtgctaat cctgctgcta tttttatgtg tttcatattt gtatacctcc atattttact
    98341 ttaattagta ttaaatatta gtttttgata ttttttaatc cagtattact tttatttagc
    98401 attactttta ttgctgtata tatttctttt atgaacttat tctgcttttg ttaactgtga
    98461 acttattttg ctttgtaaat taatattaca ctgatatatt ttttttcaca acactttgac
    98521 tactccttaa aagtaccttt atattgtggt aaattataga cattaattgt atataaaaag
    98581 ttagtttttt accacattct tatggcattt attgtctata ctaactcaat tgatatagct
    98641 agttcattta atatataatc agactataaa tataaattta ctcgataaaa agtaccattc
    98701 ataacaatat taatgaaagg gagatgtaaa atgagaaact gtattattgc ccaatctgga
    98761 ggccctacag ctgttatcaa tgcttctgca gttggtattt atgaaaaaaa tttagaaact
    98821 aaatactttg ataaagtata ttttggtatc aatgggattg aaggtatatt aaacaaaaat
    98881 ataatagatt cagactcctt aaacaaagat aatgtattaa atttaaagca aacaccttcg
    98941 tctggtcttg gttcttgtag atacaaactg gctgattata aaataaattc ttatgattat
    99001 gatagagtta taaatatact agatgaatat gaaatagata cattatttta tataggcgga
    99061 aatgattcta tggacacagt gatgaaattt tctcaatact gcaaaaacac tacttgtaaa
    99121 ataaaattta tagggattcc taaaacaata gataatgatt tattaggaac tgacaactgt
    99181 cctggatttg gttctgctgc aaagcttatt tctacactaa taatggaaac atacttagat
    99241 ttttctatat acaaaaataa tggtatattt atagtagaaa ccatgggtag agatactgga
    99301 tggttagcag cttcttcttc actagctaga cttaatgata ctccacttgt tgatttaata
    99361 taccttccag aaattgattt ctatgaagat aagtttatag aagatgttag aaaaatattt
    99421 aaagaaaaaa ataaggctta tatagttgca tcagaaggta taagggataa atacgggaac
    99481 tttatatgcg aacaaaaaac ttctgctcat gataaatttg gtcattccca attaggtgga
    99541 gtaagcaact atctaaagaa tcttatagta tcatcatcaa ttacaacaag agtaaaaacc
    99601 ttagaacttg gtgtaataca aagatgtgct atgcatttag cttcagatac tgatttaaaa
    99661 caagcagctg aagttggtgc atatgggata gaactatcta aaaaaggata tacaggagtt
    99721 atggctatca ttaatagaac atgcaataat ccttataagt atgaagttag tcatactgat
    99781 atttctaaaa tagctaacaa gacaaaatat tttcctaaag agtggataaa tgaagaatgt
    99841 aattatataa ctgatgaagc cctaaattat ctatatccac ttattcaagg taaaccagat
    99901 atcaaatata aaaatggact accttatttt tcaattattt actaggaaat tattataatt
    99961 tgatatacac tcaattctat cgctcttaaa tacctaagtg gctgttaaat aaaattataa
   100021 attgttatat gacagtcact taatcgttta attatttaac tgtttagttt tttaattttt
   100081 taatcttttt taatactaat acgatttgtt gtaataatat ctcacaccca ttttcatttt
   100141 ggatagatta taattagtta gacaataaat attttgtcat gatattatta tatatagtga
   100201 tacaaataga aatactttta tcatgactag aaaaacaaag attacacaaa ggatttaaaa
   100261 atcaaacaac ttcaattaaa ataaatggtt aaaataactt ctaaatcaac tacataaaca
   100321 ataaaagaac ataaagtagt taaatctaca attataaaat tggtaagact ataataactt
   100381 aaataaaatt aaagttaaca aagactatta aagttagcaa atattcctct acctaaataa
   100441 ttgcttttta taaagagtta tttattttaa tttattttaa ttgaaatacg attttaacta
   100501 gaacaataga ttaatgtaat atttaatata aaataattat aataattgaa aaggaagtaa
   100561 tctatgatga aaatagcagt cataacaacc gaatttttaa aagagtttgt agataattct
   100621 ataaaaaagt taaatattaa tgcagaaatt gaaatatata tctatagaga tttttctcat
   100681 gttggagatt tatatttaga aatagaagat aggtttgatg gatttgcagt tagtggcccc
   100741 atccccaaaa aagctattac aaaaaaggct ggaactatta aaaaacctct a
//
LOCUS       DAEQJM010000005        99960 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.005, whole genome shotgun sequence.
ACCESSION   DAEQJM010000005 DAEQJM010000000
VERSION     DAEQJM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 99960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99960
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.005"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            690..1892
                     /locus_tag="KRQ43_000430"
     CDS             690..1892
                     /locus_tag="KRQ43_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH2740804.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIVGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRTDNGT
                     LIVFYVKE"
     gene            1897..2667
                     /locus_tag="KRQ43_000431"
     CDS             1897..2667
                     /locus_tag="KRQ43_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740805.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSSIEVVNEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYENYAVDAFSLDVFDYVLKP
                     YSEERIISMLNKLEKSEMSDIELSNSNSNLYKYKKETVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            2813..4234
                     /locus_tag="KRQ43_000432"
     CDS             2813..4234
                     /locus_tag="KRQ43_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH2740806.1"
                     /translation="MVSFLGSIVVLIVGYFIYGTFVEKVFGINDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGIVVAI
                     ILGLLFFKKAKDIKEQNAHKLAS"
     gene            4418..4900
                     /locus_tag="KRQ43_000433"
     CDS             4418..4900
                     /locus_tag="KRQ43_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH2740807.1"
                     /translation="MDTKKYKDKLLKEREKLTNLVVDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDSALSKIENGTYGFCDLCHNQI
                     DLERLDILPDTNLCNNCAKKENALLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGTLRD
                     "
     gene            4950..5729
                     /locus_tag="KRQ43_000434"
     CDS             4950..5729
                     /locus_tag="KRQ43_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH2740808.1"
                     /translation="MKKAIWGICICLLSIVGVYTYNHNTHNQNSSKETYTLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQILDILKKNNVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYGSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDTIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            6039..6485
                     /gene="lspA"
                     /locus_tag="KRQ43_000435"
     CDS             6039..6485
                     /gene="lspA"
                     /locus_tag="KRQ43_000435"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBH2740809.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRVIWEYVFNVADVFVVVGTVFLCIYVLFFESKSR"
     gene            6454..7401
                     /locus_tag="KRQ43_000436"
     CDS             6454..7401
                     /locus_tag="KRQ43_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH2740810.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKAKYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDFVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEAIKKIK"
     gene            7760..8293
                     /gene="pyrR"
                     /locus_tag="KRQ43_000437"
     CDS             7760..8293
                     /gene="pyrR"
                     /locus_tag="KRQ43_000437"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBH2740811.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            8577..9788
                     /locus_tag="KRQ43_000438"
     CDS             8577..9788
                     /locus_tag="KRQ43_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBH2740812.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKIVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLLLRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISIGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            10087..11739
                     /locus_tag="KRQ43_000439"
     CDS             10087..11739
                     /locus_tag="KRQ43_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH2740813.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEYLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGLLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLLEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGCFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYIISRNKKTPSRDKQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQITKLKNSF"
     gene            complement(11954..13729)
                     /locus_tag="KRQ43_000440"
     CDS             complement(11954..13729)
                     /locus_tag="KRQ43_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HBH2740814.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEIANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIVLSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            14025..15059
                     /gene="ltaE"
                     /locus_tag="KRQ43_000441"
     CDS             14025..15059
                     /gene="ltaE"
                     /locus_tag="KRQ43_000441"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBH2740815.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            15346..16176
                     /locus_tag="KRQ43_000442"
     CDS             15346..16176
                     /locus_tag="KRQ43_000442"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBH2740816.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGVLEV
                     "
     gene            16180..17061
                     /locus_tag="KRQ43_000443"
     CDS             16180..17061
                     /locus_tag="KRQ43_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBH2740817.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            17091..17708
                     /gene="gmk"
                     /locus_tag="KRQ43_000444"
     CDS             17091..17708
                     /gene="gmk"
                     /locus_tag="KRQ43_000444"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBH2740818.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            17711..17977
                     /locus_tag="KRQ43_000445"
     CDS             17711..17977
                     /locus_tag="KRQ43_000445"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBH2740819.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            17982..19181
                     /gene="coaBC"
                     /locus_tag="KRQ43_000446"
     CDS             17982..19181
                     /gene="coaBC"
                     /locus_tag="KRQ43_000446"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBH2740820.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLAFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            19420..21945
                     /gene="priA"
                     /locus_tag="KRQ43_000447"
     CDS             19420..21945
                     /gene="priA"
                     /locus_tag="KRQ43_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBH2740821.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNEIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            21963..22403
                     /gene="def"
                     /locus_tag="KRQ43_000448"
     CDS             21963..22403
                     /gene="def"
                     /locus_tag="KRQ43_000448"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH2740822.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            22418..23347
                     /locus_tag="KRQ43_000449"
     CDS             22418..23347
                     /locus_tag="KRQ43_000449"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBH2740823.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTIYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            23357..24109
                     /locus_tag="KRQ43_000450"
     CDS             23357..24109
                     /locus_tag="KRQ43_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HBH2740824.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNVGELI
                     KLKEKTNVKIFVATGGTLARKIIMDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIDFLTGKNILICN"
     gene            24178..24879
                     /locus_tag="KRQ43_000451"
     CDS             24178..24879
                     /locus_tag="KRQ43_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBH2740825.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            24941..26266
                     /gene="rsmB"
                     /locus_tag="KRQ43_000452"
     CDS             24941..26266
                     /gene="rsmB"
                     /locus_tag="KRQ43_000452"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBH2740826.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            26274..27305
                     /gene="rlmN"
                     /locus_tag="KRQ43_000453"
     CDS             26274..27305
                     /gene="rlmN"
                     /locus_tag="KRQ43_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBH2740827.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGNIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            27325..28077
                     /locus_tag="KRQ43_000454"
     CDS             27325..28077
                     /locus_tag="KRQ43_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBH2740828.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            28094..30109
                     /gene="pknB"
                     /locus_tag="KRQ43_000455"
     CDS             28094..30109
                     /gene="pknB"
                     /locus_tag="KRQ43_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBH2740829.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     EEEEEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGSSNSGNSGGNSGNNGGNSGGSNSGNSGGSSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            30217..30954
                     /locus_tag="KRQ43_000456"
     CDS             30217..30954
                     /locus_tag="KRQ43_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH2740830.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVENMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            31052..31936
                     /gene="rsgA"
                     /locus_tag="KRQ43_000457"
     CDS             31052..31936
                     /gene="rsgA"
                     /locus_tag="KRQ43_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH2740831.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            31941..32612
                     /locus_tag="KRQ43_000458"
     CDS             31941..32612
                     /locus_tag="KRQ43_000458"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH2740832.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            32621..33262
                     /locus_tag="KRQ43_000459"
     CDS             32621..33262
                     /locus_tag="KRQ43_000459"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBH2740833.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTVSVTAI
                     KGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            33393..34022
                     /locus_tag="KRQ43_000460"
     CDS             33393..34022
                     /locus_tag="KRQ43_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH2740834.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            34077..34733
                     /locus_tag="KRQ43_000461"
     CDS             34077..34733
                     /locus_tag="KRQ43_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH2740835.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGASIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            35148..35864
                     /locus_tag="KRQ43_000462"
     CDS             35148..35864
                     /locus_tag="KRQ43_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740836.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMRLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVNIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAINTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            35839..38172
                     /locus_tag="KRQ43_000463"
     CDS             35839..38172
                     /locus_tag="KRQ43_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH2740837.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGGA
                     KNPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLL
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(38489..41167)
                     /gene="mngB"
                     /locus_tag="KRQ43_000464"
     CDS             complement(38489..41167)
                     /gene="mngB"
                     /locus_tag="KRQ43_000464"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH2740838.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISNIENYIDSVKNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTANEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESSKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERSIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLLFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNNSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(41242..42348)
                     /locus_tag="KRQ43_000465"
     CDS             complement(41242..42348)
                     /locus_tag="KRQ43_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH2740839.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            complement(42462..42770)
                     /locus_tag="KRQ43_000466"
     CDS             complement(42462..42770)
                     /locus_tag="KRQ43_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH2740840.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            complement(42773..43225)
                     /locus_tag="KRQ43_000467"
     CDS             complement(42773..43225)
                     /locus_tag="KRQ43_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2740841.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGIATNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            43459..45387
                     /locus_tag="KRQ43_000468"
     CDS             43459..45387
                     /locus_tag="KRQ43_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH2740842.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITISRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQNNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            complement(45647..46408)
                     /locus_tag="KRQ43_000469"
     CDS             complement(45647..46408)
                     /locus_tag="KRQ43_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2740843.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            46627..47103
                     /locus_tag="KRQ43_000470"
     CDS             46627..47103
                     /locus_tag="KRQ43_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH2740844.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            47201..47353
                     /locus_tag="KRQ43_000471"
     CDS             47201..47353
                     /locus_tag="KRQ43_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HBH2740845.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(47513..47701)
                     /locus_tag="KRQ43_000472"
     CDS             complement(47513..47701)
                     /locus_tag="KRQ43_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBH2740846.1"
                     /translation="MAKVCSVCDKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            48062..48412
                     /locus_tag="KRQ43_000473"
     CDS             48062..48412
                     /locus_tag="KRQ43_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH2740847.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            48431..50074
                     /locus_tag="KRQ43_000474"
     CDS             48431..50074
                     /locus_tag="KRQ43_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBH2740848.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            50155..52212
                     /gene="recG"
                     /locus_tag="KRQ43_000475"
     CDS             50155..52212
                     /gene="recG"
                     /locus_tag="KRQ43_000475"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBH2740849.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIRNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMERFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            52271..52825
                     /gene="rsmD"
                     /locus_tag="KRQ43_000476"
     CDS             52271..52825
                     /gene="rsmD"
                     /locus_tag="KRQ43_000476"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBH2740850.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNVKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            52827..53324
                     /gene="coaD"
                     /locus_tag="KRQ43_000477"
     CDS             52827..53324
                     /gene="coaD"
                     /locus_tag="KRQ43_000477"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBH2740851.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            53328..53852
                     /locus_tag="KRQ43_000478"
     CDS             53328..53852
                     /locus_tag="KRQ43_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740852.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            54196..56115
                     /locus_tag="KRQ43_000479"
     CDS             54196..56115
                     /locus_tag="KRQ43_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH2740853.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQERFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISKEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKSVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            56128..56415
                     /locus_tag="KRQ43_000480"
     CDS             56128..56415
                     /locus_tag="KRQ43_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2740854.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            56548..57807
                     /locus_tag="KRQ43_000481"
     CDS             56548..57807
                     /locus_tag="KRQ43_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBH2740855.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISKFIGSLFGGIL"
     gene            57810..58550
                     /locus_tag="KRQ43_000482"
     CDS             57810..58550
                     /locus_tag="KRQ43_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH2740856.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQILVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            58873..60183
                     /locus_tag="KRQ43_000483"
     CDS             58873..60183
                     /locus_tag="KRQ43_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH2740857.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            60281..61198
                     /locus_tag="KRQ43_000484"
     CDS             60281..61198
                     /locus_tag="KRQ43_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH2740858.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVKRDNSDF"
     gene            61214..62023
                     /locus_tag="KRQ43_000485"
     CDS             61214..62023
                     /locus_tag="KRQ43_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH2740859.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            62080..63828
                     /locus_tag="KRQ43_000486"
     CDS             62080..63828
                     /locus_tag="KRQ43_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HBH2740860.1"
                     /translation="MEISYVLKDCTFKHNKYSVIEAETWKEKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSTISWKGLENRVRLALNVPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLNIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDKSKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMSKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDENDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIENLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            64091..65113
                     /locus_tag="KRQ43_000487"
     CDS             64091..65113
                     /locus_tag="KRQ43_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HBH2740861.1"
                     /translation="MFGGINIKRIGIIIMFFLSIAFIGFYLAIRGNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEEFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLSSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNVPKDSNIVV
                     SFHYYEPNDFAFQGNIYHNGFEHLSNITWEGTNEQMDYLKKRFDIVENWANKNKVKIF
                     LGEFGVTKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            65118..67424
                     /locus_tag="KRQ43_000488"
     CDS             65118..67424
                     /locus_tag="KRQ43_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH2740862.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPVISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMRILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKNKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKIRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKNIYPKEIALEINENIVLECDLCEGKIDERGLLYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTIPVSNPSEKKEKSIDEFEPMEYI"
     gene            67396..68511
                     /locus_tag="KRQ43_000489"
     CDS             67396..68511
                     /locus_tag="KRQ43_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740863.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSAKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSRITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQKINLSIQSKNMLEFRLKEGSEIFLEDKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEKSNVVLDSSMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     SFLHNIKITGNEEVQIPVLGQSISQYEVLGLKRDSKIKYSLMGKQDNVSISQNGKLTL
                     SNKAEPGQIILQVNVDDKFKIGRKIALTESWSINKKDKDGVPYTLVSPEQSPTVQYMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            68529..69947
                     /locus_tag="KRQ43_000490"
     CDS             68529..69947
                     /locus_tag="KRQ43_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBH2740864.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCVYNIGVLFIFKYLAFAL
                     RNISELINTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTMQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMLGG
                     NGVIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            69962..71170
                     /locus_tag="KRQ43_000491"
     CDS             69962..71170
                     /locus_tag="KRQ43_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740865.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNICYSGKDMIQEIKNSVAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSEEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKENYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCK"
     gene            complement(71251..72639)
                     /locus_tag="KRQ43_000492"
     CDS             complement(71251..72639)
                     /locus_tag="KRQ43_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBH2740866.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFTIHLIFITLNGLNPITYIRNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSLYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFGKKNIS"
     gene            72981..74315
                     /locus_tag="KRQ43_000493"
     CDS             72981..74315
                     /locus_tag="KRQ43_000493"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HBH2740867.1"
                     /translation="MRVVIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFDDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(74444..75361)
                     /locus_tag="KRQ43_000494"
     CDS             complement(74444..75361)
                     /locus_tag="KRQ43_000494"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBH2740868.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLNSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            75569..76453
                     /locus_tag="KRQ43_000495"
     CDS             75569..76453
                     /locus_tag="KRQ43_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HBH2740869.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRIKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGKKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            76666..78507
                     /locus_tag="KRQ43_000496"
     CDS             76666..78507
                     /locus_tag="KRQ43_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HBH2740870.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKNKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDYVVSKKVDEIKEQQEKILDKVIGATTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGERITSIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPILKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNQGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            78811..79518
                     /locus_tag="KRQ43_000497"
     CDS             78811..79518
                     /locus_tag="KRQ43_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740871.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            79512..80822
                     /locus_tag="KRQ43_000498"
     CDS             79512..80822
                     /locus_tag="KRQ43_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2740872.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMAQE
                     NYLKDTTESEETGYLVEYNEYFKEGTFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEKLEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            80939..81622
                     /locus_tag="KRQ43_000499"
     CDS             80939..81622
                     /locus_tag="KRQ43_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2740873.1"
                     /translation="MKILYTENLSKHYGKGENLVRALDNVNLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            81615..84002
                     /locus_tag="KRQ43_000500"
     CDS             81615..84002
                     /locus_tag="KRQ43_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH2740874.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFELIKGKLPTKENEIVLDSGALKALGYKNKDLGEKIKISYNDYKNDK
                     KIEKEFVISGILKTSEISEAGKYYYAIISELYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGGFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKNNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNLIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKAVISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            84281..85423
                     /locus_tag="KRQ43_000501"
     CDS             84281..85423
                     /locus_tag="KRQ43_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH2740875.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIVGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLDRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALKLTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNENLLNLFNKYYF"
     gene            85442..85966
                     /locus_tag="KRQ43_000502"
     CDS             85442..85966
                     /locus_tag="KRQ43_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH2740876.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYITEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            86066..86884
                     /locus_tag="KRQ43_000503"
     CDS             86066..86884
                     /locus_tag="KRQ43_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH2740877.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSELFAKKLEESLNPTQSVEKIVLYLEEMLLSILEEDLISNKSV
                     KLLNSFIYDNRYSNIKAFCDNTNINIKTLERICLKYTGYTPKILKRIYRFKMASSQLI
                     YNYKDNELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYNYL"
     gene            86962..87273
                     /locus_tag="KRQ43_000504"
     CDS             86962..87273
                     /locus_tag="KRQ43_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBH2740878.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(87576..89579)
                     /locus_tag="KRQ43_000505"
     CDS             complement(87576..89579)
                     /locus_tag="KRQ43_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HBH2740879.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     NFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(89732..90370)
                     /gene="recX"
                     /locus_tag="KRQ43_000506"
     CDS             complement(89732..90370)
                     /gene="recX"
                     /locus_tag="KRQ43_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBH2740880.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            90646..91335
                     /locus_tag="KRQ43_000507"
     CDS             90646..91335
                     /locus_tag="KRQ43_000507"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBH2740881.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            91336..91908
                     /gene="yqeK"
                     /locus_tag="KRQ43_000508"
     CDS             91336..91908
                     /gene="yqeK"
                     /locus_tag="KRQ43_000508"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBH2740882.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSRNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            92025..92375
                     /gene="rsfS"
                     /locus_tag="KRQ43_000509"
     CDS             92025..92375
                     /gene="rsfS"
                     /locus_tag="KRQ43_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBH2740883.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            92729..95149
                     /locus_tag="KRQ43_000510"
     CDS             92729..95149
                     /locus_tag="KRQ43_000510"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBH2740884.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            95576..95888
                     /locus_tag="KRQ43_000511"
                     /pseudo
     CDS             95576..95888
                     /locus_tag="KRQ43_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431045.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            95987..96655
                     /locus_tag="KRQ43_000512"
     CDS             95987..96655
                     /locus_tag="KRQ43_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH2740885.1"
                     /translation="METVSNNQSSVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(96813..97808)
                     /locus_tag="KRQ43_000513"
     CDS             complement(96813..97808)
                     /locus_tag="KRQ43_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBH2740886.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGIGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(97929..99557)
                     /gene="aspD"
                     /locus_tag="KRQ43_000514"
     CDS             complement(97929..99557)
                     /gene="aspD"
                     /locus_tag="KRQ43_000514"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HBH2740887.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDEI
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        38721 a        10972 c        17127 g        33140 t
ORIGIN      
        1 tattattata aaaaatttat ttatattaaa taatatgttt tatattaact tagataataa
       61 aaattttctg gaatttttat tcttatacgt gataaaaata gttataacta tgtatttcag
      121 aaaataaaat ttagaggtat tttttttaga agaattattt aacttctaat tatagaagtg
      181 actttcaagg ttggcaaatt attatggtaa atatacatta taatgattta ctatcaaaca
      241 tatgatttta aatataggat ttatttactt tatcgatata cggctatata ataaatatat
      301 aacagagaga tgataatgtg tgtttagcac aattaaatca aatgagatat ttgaacaaag
      361 aatagtataa aatttttaaa gaaatatgtt gtatgagtaa gaatctacat aacattgtat
      421 tatataatat tcgaaagtat tacttctaag aaaagagatt tctaaagtat aaaattaaat
      481 actagaattg tagagttaat gataactaca agttattaca agcttgtgtt agtcagctag
      541 tattagttgt taatagaagt atatccattt tttatttaat taaaaggtta aatgtggaaa
      601 atgtcgagat aggattactt caaatatata agttacaaca aacataataa atttagagtg
      661 tgtaaaaatt tattttttaa aggtggaata tgaaaacatc aattttaatc gcattaatag
      721 aaaagacaag cctcattgta gtactgtttc ttctaataac aaagttaaaa atatttaagc
      781 agatatttca aaaggaagaa tatagtttta atgacttggt ctgtatagca ttagttttta
      841 cttttttagc catatttgga acttatagtg gtataaatta tatggggtca atagtaaaca
      901 ctagaataat atctatagta tcaggtggca ttttatttgg tccaatggta ggtattacag
      961 caggagtttt ttcagggatt catagatatt ttatggatat tggggggata acatctgttc
     1021 catgtctttt atcaagtata ctagcaggtg tattatcagg atttctatat aagaggatac
     1081 caaagcaaca tagagtaatg tatggtatat tggtaggtat gatttctgaa agttttacta
     1141 tactacttat atacttaata tcatatccac attctttagc aattcaaata attgttggga
     1201 tatatttacc tttaattgtt ggacagattg gaataggatt tgttatatct atagtagagg
     1261 ggattgagaa agataaaaaa gatatagaag cgagaaataa agcagaaata aaagcacttc
     1321 aaagacaaat taatccgcat tttttgttta attccctaaa cacaatagct tcatttataa
     1381 gatttagtcc agataaggct agagagttaa taataaattt atcaacttat ctaagatata
     1441 atcttgaata tagtgataac ttaattgata taaataaaga gattgaacaa gttaaatctt
     1501 ttgtagagat agaaaaagct aggtttggag aattactaac tgtatcttat gatatagaag
     1561 atgtaaatat aaagattcca agtttgatta tacaaccatt agtggaaaat gcgataatac
     1621 atggtatttt agaaagtggt agagctggtg tagtgaaaat atccataaaa aagttacctt
     1681 attcattaga aaatactgtg agaatatcaa tagaggataa tggtataggt ataagtgagg
     1741 aaattataaa taatgtatat caagataata tgccagaaaa taagattgga ctttataatg
     1801 tacatttaag gcttaaactg atgtatggaa gagggcttaa tataagaaga acagacaatg
     1861 ggactttgat agtattttat gtaaaggagt agaagtatga gagctataat agtggaagat
     1921 gaatttccgg caagaaagga attaagatat tttattgaga ataaaagtag catagaggta
     1981 gtaaatgaat ttactaatgg tatagaagtg ttagacttta ttcaggaaaa taaaatagat
     2041 gtaatttttt tggatataaa tatacctcat ctcgatggaa tgcttcttgc aaaaacatta
     2101 aatcagttta aatcaaggcc taaaattgtt tttataacag cgtatgaaaa ttatgcagta
     2161 gatgcttttt ctttagatgt atttgattat gtactgaagc catattctga agagagaatt
     2221 atttctatgt tgaataaatt agaaaaaagt gagatgagtg atattgaact gtctaatagc
     2281 aatagtaatt tatataaata taaaaaagag acagtaaatc aggagataga agaaataaca
     2341 cataaaatta gcctttggaa aggtgataaa ttggttgtaa tagatattga tgatatatat
     2401 tattgtgaag ctaatgaaag gcagacattt atatatactg agaaagaaaa gtttatatta
     2461 aaagaaggca tatcagaagt agagaatctt ataaatgata aaacattttt tagaacacat
     2521 aggtcttata tcgtaaattt aaccaaagta aaagaaatta taccatggtt taacaataca
     2581 tacatattga aattaaaaaa tagtgactat gaagtaactg taagcagaag caaagtaaaa
     2641 gaatttaggc tgttaatgca tatataaagt catttcatgt acttaaatat gcacttaatg
     2701 taattaatat ttatattagc ataaaaaagt attactattt gaactggaaa tagttttctt
     2761 aaactcataa aaatttataa agcaattata taaaaactaa ggggatgaat ttatggtaag
     2821 ctttttaggt tcaatagtag tacttatagt aggttatttt atctatggta cttttgtaga
     2881 aaaggttttt ggaatcaatg acaaaaacca aactccagct atagcttgta gggatggagt
     2941 agattatgtg ccaatgaaat ggaagagaat ctttttaatt cagtttctaa atatagcagg
     3001 gttaggtccg atatttggag ctatacaagg ggcgttattt ggaccatcag catttttgtg
     3061 gattgtgttt ggaacaatct ttgcaggtgg agtacacgat tttgcttcag gatatttatc
     3121 aatgaagaac aaaggtacat ctgcatcaga gttggtaggt ctttatctag gaaatggtgc
     3181 aaaaatagca atgagaatat ttagtgttat tcttttagta ttggttggag ttgtatttgt
     3241 aacaggtcca gcaggattat taaagacatt gacaggtgta aacgcacaaa tatgggttgg
     3301 agtgataata ctttattata ttatggctac tgttttacca atagataaat tgattggtaa
     3361 aatatatcct ttatttggag cagcattatt aattatggca gtaggtgtag ctggaggatt
     3421 aataataaag gggtataaca taccaaatat aaatttacaa aatatgaatc caaatggaac
     3481 acctttattc ccatacttat ttataacaat agcatgtgga gcaatatcag gtttccatgc
     3541 aactcaatca ccacttatgg cgagatgtgt tgagaaagag agtgaggcaa gaccagtatt
     3601 ttatgggtca atggttgcag aaggtataat agctttagtt tgggcagcag cagctatgtc
     3661 atatttccat ggtatacctc agcttaatgt aatatttaat gatggtggag cagcaactgt
     3721 tgtaaataca gtatctgttg gattaatggg acctattgga ggcgctttgg ccatacttgg
     3781 tgttgtagca tgtcctataa cttcagggga tacagcattt agaagtgcta gattaacaat
     3841 agctgatgca atgaattata atcaagatgc agttaaaaat agatttttaa tagctttgcc
     3901 attatttgct gtaggggttg cccttacatt tatagatttt aatataattt ggagatattt
     3961 ctcttgggca aatcaaacac ttgctatgat aatgttgtgg actggttctg catatttagt
     4021 caaagcaaat aaaaatcatt acataactac attgccagca ctttttatga ctgtagtaac
     4081 atttagttat ataatgcagg caaaagaagg atttagactt ccagttaata tatctaatgg
     4141 aataggtatt gtagttgcaa taatccttgg acttttattt tttaaaaaag ctaaggatat
     4201 aaaagagcaa aatgctcata aattagcaag ttaatgtaat tattatcaaa aactaaaaac
     4261 attatattaa aaatatatgt aaagaatttg taggtgaatt ttaagtttac ctacaatttt
     4321 ttttgaaaaa atcaaatctt gttttttatt gtatttttaa tttagttttc cacatactat
     4381 ttttatgata taaatattaa aattagaggt gttgaaaatg gatactaaaa aatacaaaga
     4441 taaattatta aaagaaagag aaaagttaac taatttagtc gtagatatga aagataatac
     4501 cttgtttgga gacactacta aacatactag tgaaaaatat tcatcaggag aattatctag
     4561 ttatgacaat catattggag atatgggaac ggatttatat atgcaaaata tgcaaaatag
     4621 tttaataaat catgaagaag gaagactgta tcaaatagat tcagcattat ctaaaataga
     4681 aaatggaaca tatgggtttt gtgatttatg tcacaatcaa atagatttag aaagattaga
     4741 tatattacct gatacaaatt tatgtaacaa ttgtgcaaaa aaagaaaatg ctttattagg
     4801 tgatgcaatg caaaatcctg atgtagaaga ttctaacttt tattcagaag acctaacaaa
     4861 tttaactgat ttaaataaaa atggaacatt gagagattag aagcctgaca tcatatattg
     4921 ttagaatgaa ttagaaaaga ggtaatgaca tgaagaaagc aatatggggt atatgtatat
     4981 gtttattatc catagtaggt gtatatacat ataaccataa tacacataat caaaatagtt
     5041 caaaagaaac ctatacttta aatgacaata taaaagacga ttatgaagat gtaataataa
     5101 aaaaaggaaa tgaggatgaa aagattctag cattgacttt tgatgatggt ccagatgagg
     5161 attttacacc acaaatactt gatatattaa agaaaaataa tgtaaaagca actttttttg
     5221 tagttggaga aaaagtagaa tataacaaag aattattaaa aaggcaatat gatgaggggc
     5281 atgaaatagg gaatcataca tttacacata taaatgttgc aaaaaatagt tatggtagtg
     5341 ttgaaaaaga aataacagat acacaaaata ttataaaaag tgtaatagga gtagaaccaa
     5401 agatatttag acctccatat agagccatga gtaaaagtgt ctgtgatatt atagtttcta
     5461 aaggcatgaa tataattctt tggtcaaact tagaccctag agattggtct aaccctggtg
     5521 tagatacaat tataaatact attcttacaa aggtccaaaa tggtaatata atacttttac
     5581 atgattataa cactaaaaga aatgataaat cacaaactat acaagcttta gaagtagtaa
     5641 ttcctaaatt aaaagagaga ggatataaat tcgtaacagt atctgaactt atacaacatt
     5701 tagataaaaa taagcaagtg caaaagtaaa aatatttgtt tgaagattag tggtgcttgt
     5761 aagtttaaag tacagacatc attaatcttt aatctataaa acacacaaaa agtattaatt
     5821 agtatgttat ttttaaattt tttatacata ataatatgat tttaaatatg tagcaatctg
     5881 caatataaaa aagatggtac tattttaaat tttgctctag ctttattaag aaaatacaat
     5941 tttaataaag ttgctcttta gagcattttt tttgtataat aataatagtg tgtttcaaat
     6001 aaaattggtt tttaaataat ttataggggg aaaaatcatt gctatatata ttaataataa
     6061 ttctactcat aggcttagac caactgtcta aaatatgggt attgaataat ttggtagatg
     6121 tttcaacaat accaataata aataatgtat ttcatttaac ttatgtcgaa aatagaggtg
     6181 cagcatttgg attattacaa aataatcagt ggatatttat aattgttgca ttacttgcaa
     6241 cagtatttgg attatactat cttaatacaa ggaaagtaca tatatttgga aggttgggaa
     6301 ttatattaat tatatctggt gcattaggaa atctaattga tagagtacga ttaggttttg
     6361 tggtagatta cttcgacttt agagttatat gggaatatgt attcaatgta gctgatgtat
     6421 ttgtagttgt aggaactgtg tttttatgta tatatgtttt attttttgaa agtaaaagta
     6481 ggtgatataa tggatgaagt aaaagagttt ttagtacttg aagaggaaga agaagttaga
     6541 cttgatattt atctagcaga acaattaggt gatatgtcaa gaagttatat acaaaaaatt
     6601 ataaaagatg gaaaagtaaa ggtcaataat aaagtagaaa aagctaaata tctagttaaa
     6661 gaggaagata atattgttat agagatacca gaacctaaag tattagaggt tttacctcaa
     6721 gatattccaa tagatattgt atatgaagat gatgatgtct taataataaa taaaccccag
     6781 gatatggttg ttcatcccgc tcctggaaac tatgaaaata cactagtaaa tgggatttta
     6841 tatcattgta aagataagtt gtcgtcaata aatggagtta ttagacctgg tatagttcat
     6901 agaatagaca aagatacttc tggtcttctt atgatagcta agaacaatta tgcacataat
     6961 tttctagcag aacagttaaa ggaacatact ataactagag agtatgaatt tatatgctat
     7021 ggtgtggtta aagaagataa aataactgtt gataaaccta tagggagaaa tcctaaggat
     7081 agattaaaaa tggctgtagt aaaggatgga aaaaatgcaa ttactcattt tgaagttgta
     7141 gaaagatttg ataagtttac acatatgaga gctaggcttg aaactggtag aactcatcaa
     7201 ataagagttc atgctttgtc tataaatcac ccacttttag gtgattttgt atatggtcca
     7261 aaagaaacta aatttaaatt aaaaggacaa actttgcacg ctaagaagtt gggatttata
     7321 catcctacca ctaaggaata tatcgaattt aattcagaat tacctgagta ttttaaggaa
     7381 gctattaaga agataaaata accatttgta taatacttat aaatcatttt ttgtttttat
     7441 ataagtaaat aaatttagtg aaatttaaat aaaatatctt atattaaagt attttgttta
     7501 aaaaagcttg aaaaatttga aatataaata tataatttga gttgatagat taaaaaatta
     7561 tctttaaacg atacagagat atcgtaagac aattgctaaa ttacactgta tattttttat
     7621 ataagagctt cttgtcttgt gatgagaagt tttttgttgt ttaaattgaa attttaaata
     7681 aaaataaatt tataaaaaat taaaagaaag gagtagattt gtcaaataga tatattatat
     7741 ctttgacaat aattatgata tggtagaaaa agctcaatta atggatgaaa aggcaatagc
     7801 aagagcaatt actagaataa gtcatgaaat aattgaaaga aataaaggtg tagaaaatct
     7861 agttttagtt ggaataaaaa ctagaggtgt gccaattgca aatagaattt ctaagaaaat
     7921 agaacaaata gaaggaacaa aagtagatac aggagatatt gatataactt tatatagaga
     7981 tgatttggaa aaaattcatg ttgaacctgt agttaaagga acttatttag attttaatgt
     8041 aaatgataag acagtagttt tggttgatga tgttttatac actggaagaa ctgtgagagc
     8101 ttcactagat gcgattatag atataggaag acctaaatca atacaattag cagttctagt
     8161 ggacagaggg catagagagt tgcctataag agcagattat gtaggaaaaa atgtacctac
     8221 ttctagacat gaaattatat ctgtcagttt attagaaatt gatggagaag attcagttac
     8281 aatcaaagaa taattagttt taagtattat ataaaagctt agcattgaat agtcagggag
     8341 gaggataaag cttacataga ttgcacaaaa taaatattat aattttatgg atgtgagtct
     8401 taatgtagtt tttattctcc tttatttgag tttttgatgt cgtaaaatgt aaaataatga
     8461 taaattatat aataagtata tagaggttaa aaaatagaat ctagggaatg ataattaatt
     8521 aaaagatatt aattaaacag aggatttatt tatatataat aattttggag gtttttatga
     8581 aaaaaacaat aatgtcttta caacatctat tagccatgtt tggagcgaca gtattagttc
     8641 ccattttgac aggttttaat ccgtcagttg caattttctg tgctggtgtt ggtacattga
     8701 tatttcattt ttgtacggaa ggaaaagtac ctgccttttt aggttcaagt tttgcgttta
     8761 taccagttat actagcagct aaagaggcgt atggtggaga tttagcatat gctcaaggtg
     8821 gtataatagt agcaggatta atttatatta taatgtcgat tatagtaaaa atagttggtg
     8881 taaataaaat taaattatat tttcctgcac aagttacagg agctatgata gtagttatag
     8941 gattaaattt attgccaaca gcttttagta tggcttcagc taattttgta atagcattta
     9001 taactttagc aatagcaatt ttaaccaata agtttggtag aggatttata aaacaattag
     9061 gaatattaat agccgttttt tctgggtata taatctgttt actgttaagg ttagtagata
     9121 taactactat tacagaagca agtttatttg caataccgaa ctttacagtt cctaagttca
     9181 gtttaggagc aattgtgatt atatctccag ttgtattagc tgtatttatg gaacatatag
     9241 gagatatgac tactaatggt gctgtagtag gtaaaaactt tatagaaaat ccaggattaa
     9301 atagaacatt acttggggat ggatttgcga ctatagttgc agggtgttta ggaggaccag
     9361 ccaatacaac ttatggagaa aatacagcag tacttgctat aactaaaaac tatgaccctt
     9421 caatacttag acgtacagca atatttgcta tattgcttgc atgtgtagga aagtttggtg
     9481 gatttcttca aagtatacca ggttcagtta tgggtggaat tagtataatg ctattttcaa
     9541 tgataactta tgtaggatta aaaactataa gggacagttc ttgtgtagaa agtaagataa
     9601 atatattaat aatagcagtt atattattaa taggtcttgg aacaacatat ttatctaata
     9661 aaggcatttc tattggaatc cctataacaa gtacagtaaa gataactggt cttagtttag
     9721 ctgcaattgt tggaattgta ttaaacagaa ttttaaataa tcaggatttt aaagttgaag
     9781 aagaataaat ttaaagaata aattgtatat tgaataacta aaattagtta attttctata
     9841 gacatttgta attaatgttg atataatgat taaaaataaa tgaaagaaag ggcaaggtaa
     9901 ctaggacaat gagaatataa tctatttttt ataatttaaa gtattgtaat ttttgaaaag
     9961 cctattttga tggctttatt tgcaatgctt aaattaagga gagtagatta tagtctatac
    10021 gtttatttgt tatgcctatt tatagaatct ctccttatat ttaagtgtgt taaggaggga
    10081 ttttttatgt tgttagtaaa agtagagaat ttaaagaaat attatgcaga taaattaatt
    10141 ttggatatag ataaacttga aatattagaa aatgacaaaa taggtctagt tggttcaaat
    10201 ggtcaaggaa aaacaacatt attaaaagca atattgggtg aaatagaaat tgatgaagga
    10261 tatacttacc ttacagaaag ctattcttat ataagtcaga gtgaaaataa tattgaaaca
    10321 tgtagtcata gtaaggagaa gagtctttta aatgctccag ataaatttga agaatactta
    10381 tcaggagggg aaaaggttaa gttaaaaata gcagatgcgc tgagtaataa gaaaaatatc
    10441 ataatagctg atgagccaac ttcaaactta gataaaaaaa gcattgggct tttggaagat
    10501 atgtttaaaa ggcatgaggg agcattatta ttaatatctc atgatagacg ttttctggat
    10561 gagttatgta caactatatt agaactagaa gatggaaaac taaaagctta caaaggcaat
    10621 tacactgatt atttaatgca aaaagatgaa gaagtaaaaa gagctgattt tgagtatcaa
    10681 gaatatgtta aagagaaaaa aaggcttgaa aaagctcttt tatataaaaa agctttaagt
    10741 gatggcataa gaaagacacc aaaaagaatg ggtaattcag aagctaggtt gcacaaaatg
    10801 ggtggtcaga ctaataagaa aaagttggac tcaaatgtga aggctataaa aagcagaatt
    10861 gataaacttg aggtaaagaa taaacctaaa gtttctaaag aaatgaacat taagattcaa
    10921 gatggtatgg agataattag caaaaatcta ttagaggtaa aagatatgac tctaaagtta
    10981 gaaaataagc tcttgttaga taatgtttcc tttaagataa aaagaggtaa aaagatagca
    11041 ttattaggtg ataatgggtg tggaaaaagt actctgataa aagaaatatt ggctgataaa
    11101 aatgacaata taaaaataaa taacaaggta aaagtaggtt gttttgacca aaatcaaagt
    11161 ttattagatg aggaaaagag tgttctatac aatactaaag ttaatagttc atttgatgaa
    11221 tcttttataa ggataaactt aagcctattt gggtttaaag gtgatgatgt ctacaaaaaa
    11281 gtaaaagtac ttagtggtgg agaaaaggta aaaatagcac tatgtaaaat aatattggaa
    11341 gataataatt ttttagtatt tgatgaacca acaaattact tagatataaa atctatggaa
    11401 gcactggaaa aggcactgat aaatactgat aaaactatgc ttatagtgtc tcatgataga
    11461 gtatttgtat cacatatttg taactatatt atagagataa aagatgctaa aataagggag
    11521 tttgattgta attatgacga atatataatt agcagaaata aaaaaactcc tagtagagac
    11581 aagcaaatca aaaaagagaa tcttctagta ttagaaaata gacttacaac tgttatatct
    11641 atgttatcta tagaaaaaga taatctaaaa aaagaattgt atgaatcaga atataatgaa
    11701 ttactaaaac aaatcactaa attaaaaaat agcttttagt gttaactttt taattacatc
    11761 tatataagaa gactgaaaat atttgttggg aatataagta tagttattaa aacagaaaag
    11821 tattttgtta gaaaattaaa agtaagctaa ttagaaagtg gccttattat tgtactttat
    11881 aagaaggcca ctatttttat ttagaatgat aatgtgtgct tgtctaacat ttattttgta
    11941 tttagtgcag aatttattca gatttaacct taagcttggc tactgtttct tcttcaggag
    12001 taacataaat agtactgtta gtttcataaa taaccatacc tggtttagaa ccactaggtt
    12061 ttttcacatt ttttctctta gtatagtcta caggcacctg agaagaaagt tttgacttac
    12121 taaagaatgc tgctagcata gctccttcaa atacagtatt atcagggact tccttaccag
    12181 cacactttat tattacatga gaaccaggaa tattctttgt atgcatccat aagtcatcat
    12241 tatcagcaag tcttagtgta agatagtcat tttgcttatt gtttttacca accaatattt
    12301 taaatccatc agaagacaca aattcatgag gttttgtaga tgggatagta tcctttttac
    12361 tgtttttctt ttgagtcttg atatatccaa ccttagcaag ttcttctttt atatcttgta
    12421 attcagctaa attttcgcag ttttcaatac ttaaaactat gttttctaag taatctattt
    12481 cttccttatt taaggaaatt tgatgagata tctcgacttt agcatgtttc attttgttat
    12541 actttttaaa gtatttttga gcattttcag atggtgtcaa gtttttattt aattctattg
    12601 ttacatcatt acaattttca tcatagaagt tagcaatttc aatactttcc ataccttttt
    12661 ctaccatata aatatatgaa gtaatcaatt ctccttttat cttataaatg tctgcatttt
    12721 cggattctga taattcttct tcttgttttt taagtttatt ataaagtcta tcaagcttaa
    12781 cagatatact cttctttaaa tcagatgaac gttgattaat tctgtcttta atatctttag
    12841 ttctatagaa atcttctaga atacgagaca tactatcctt atttatatat gataaatcgc
    12901 taaataatgt aaggtttata caactgaaat caactacctt atccaccttt ttatctataa
    12961 taatgcaagg ggagtatttg ttagaattta tatcattgaa taaattacaa aatactttgt
    13021 gtaaagaatc aaattgttca tcagatatat cctttatgat agcattttga tttacacctg
    13081 ctctgtagca aatttcttta gctataatag ggcttatacc tagaaattta gaatatatag
    13141 acttaaagat aggtccttcc aattcttcta ggtttttaat aaacaaatcc ttagatatat
    13201 catcaagagg gttgagtttg ttttgttctg gtggtaatga ataatcatga ccaggtaaaa
    13261 cttgacgaac tctacttatg ctaaaaggga ctctttttat agaatctata attttatttt
    13321 cttcaccatg agttattatt atgttgctat gtcttcccat aatttcaatc ataatatttt
    13381 taactgtctt ttcttttaat tcatctaaag attcaacact tatttttatt attctttcaa
    13441 aacctatttg agaaatttct actatatttc caccttgtat gtattttcta agtaacatac
    13501 aaaacatagg cgcttttaga gggttttctt tttgataatt acttgtaaga taaactctag
    13561 gatttgaggc acttgcactt aaaaccaatc taaaattttc tttattattt cttatattaa
    13621 aaattacctc atcatcttca ggttgatgta tcttatctat ttttccacct gtaagttttg
    13681 atgataattc atcgactatt gaatgtataa ctaatccatc taatgccatt tatagcaccc
    13741 ctttctttga ccaaaatgag tcagtaaatt aattatacac ataatatacg ctttgtgact
    13801 agggggaatt taaacgatag agattaatat ttaaattgta taattattta tacttattag
    13861 agaggaaact ttatttttaa aattaataat ttaaagtaga ttaaatataa agtaaatata
    13921 gtataattat tgtgtagagt ataagctatg aaagtatatg aactttacag aaaaaatcaa
    13981 ttttaaggtt ctatagtata taaatatgaa agaaggttga aaaaatgaga tttatcgatt
    14041 taagaagtga tactgttact atgcctactg acgaaatgag agaagctatg gcaaaggctc
    14101 ctgttggaga ttcaatcttt agagatgacc ctactgtaaa taaacttgaa gaattagcag
    14161 cagctaaagt tggaaaagaa gatgctattt tccttccaag tggaactttt gggaatcaat
    14221 tagctctatt tactcattgc ctaagagggc aagaaataat tattggtaaa ggttatcaca
    14281 ttgtaactca tgaggttggg gcacctgctg taatagctgg agttcagctt agaactatag
    14341 atgaagacga aagtggagct ctaaatcctg aacttgttga aaaggcaatt agaagagatg
    14401 acatacatga accacagaca gggcttatat gtgtagaaaa tgcatattca ggtggaactg
    14461 ttgtgagtct tgataattta agagaaatta aaaaaatagc tgagaaacac aacttaccag
    14521 tacatttaga tggagcaaga ttatttaacg cagcattaac tttgggtgta gaagctaaag
    14581 aaatagcaaa gtgttgtgat agtgttatgt tctgtgtgtc aaaaggttta gctgcaccaa
    14641 tgggttctat acttgctgga agtaaagaat ttatagcaaa agctagaaga aagcaaaaag
    14701 ttatgggtgg gggaatgaga caagtaggta tagttgcagc agctggtata attgccattg
    14761 aaaaaatgac tttaagattg aatgaagacc atgaaaatgc aaaatattta gcttgtgaat
    14821 taaataaaat tgatggcatt gaagtaaaca atgttaatcc agatataagt atggtatttt
    14881 ttaagatgag tgaagatatt ataaaagagg atgttttaat aaaagaattt tttgaaagaa
    14941 atataaaaat taataaaatg gaaaatggtg aatatagatt tgtaactcat gtagatatta
    15001 ctaaggaaga tttagactat gttttaaaaa cacttaaaga attaataggt gtatgttaat
    15061 agatatctac taaaaggatt atagctggtt accagatgtt taattaaaaa attcatagac
    15121 agtttaaata aaacatacat aaaattcata tagaaatatt aatatataaa catagaaaga
    15181 actagcttaa aaacataata taattaccct aattgtaatg acaactctcc ctcacatcct
    15241 caaattatag ttgtcattac aaaacttttc ccataaatta taagtttatg ggaatttttt
    15301 tatgttataa tagtttaagc gttaatttac gaaggagcga tacttatgaa attttggaaa
    15361 ctacatggaa taggaaatga ttttatagca atagatggaa gattcgacca gataaatcca
    15421 tctgattata ctgctttagc aaaaaaagta tgccatagaa gattttctgt aggagcggat
    15481 ggattgttag ttgtgaaaga ttcaaaagtt gcagatgtag aaatggtata ttataattct
    15541 gatggttcaa gagcagctat gtgtggaaat ggccttagat gtttttgtaa atttgtttat
    15601 gataattgta tagttaaaaa agaaagtttt acagtagata cattagatgg tataaaagat
    15661 ataaaaataa atcttaccaa tagagaaata aactctataa gagtcaatat gggaaaagga
    15721 agttttatag ctaaggatgt tcctgtactt acaaataaag aacgttttgt gcaagaaagt
    15781 ataaaggttt tagataggga gcttaaagtt acttctatgt tgatgggggt tcctcataca
    15841 gtagttatag tagatgaatt agatgtagat gatgtttgta aatatggaaa agagattgaa
    15901 aataataaaa tatttcctga aaaaacgaat gtaaattttg taaaggtaga agataagtat
    15961 aatatacatg tttatacttg ggaaagaggt tgtggatata ctttaggttg tggtactggt
    16021 atgactgcat cagcaatagt gtgcaattta cttaatatgg tagaaagtag tgtaaatgta
    16081 acgtctcaag gtggaacagt taaaatagat gtaggagatt tctcttatat gacaggtcca
    16141 gcagtaaaaa tatgtgaagg tgttttggag gtttaattaa tggctataag tatgactggt
    16201 tttggaagag gagaatacaa ggatgataat tattactttt tagtagagtg taaaacgata
    16261 aatcataagt attcagatat aaacatacgt cttccaagaa aaatttcatt tttagaggat
    16321 aaagttagaa atttagtaaa aaattatgta aaaagaggaa gagtagattt atacataaag
    16381 tttgacttat taggcaaaga agatgtaaac ttaaattttg atgagggatt agcatctcag
    16441 tatatagaca tactaaaaga aataaaaaat aaatttgata ttatagatga tattagcgtt
    16501 atgaatgttg caaagtttcc tgatattgtg aaaatagaag aaaaggaaga agatgaagat
    16561 ttattgtggt caatgttgaa tcaagcagtt gaagatgcat taatcaaatt aagagaaatg
    16621 agaagtgaag aaggtaaaaa attagctgaa gatattgcca tgagatgtga tttattaaaa
    16681 aatcatatag aagagattga aaaatattca agtagtgttg tagaagatta tagagaaaaa
    16741 ttgaatttga gaataagtga attactggat gacccaagta taatagatga gaatagatta
    16801 gcacaagaag ttgcaatata tgcagataaa agcagtataa cagaagaaat agttagattt
    16861 aaaagtcata tagggcaact taaaaatact atatttaaag acgactctat aggtagaaaa
    16921 atagatttct taatacaaga gatgaataga gaaactaaca ctataggttc gaagtcatct
    16981 gatataaata taactaattt agtagtagaa gtaaaaagcg aattggaaaa aataagagaa
    17041 caaatacaaa atatagagta agaatacaat attagaaggg gaatgcttaa atgtttgtga
    17101 aaaaaggatt attgctagtt gtatcaggac catcaggtgc aggaaaaggt actatttgca
    17161 aagaactact taaagaaaat gatacaataa aactttctgt atcagctact acaagaaaac
    17221 ccagaactgg agaagttgat ggagtaaatt atttcttcat aagtaaggaa aagtttgaag
    17281 agatgataga aaaaggtgag tttttggagt atgctcaaat ttatgataat ttttatggaa
    17341 ctccaaaagc ggcaataatg gaatgtttag aaaaaggaca agatgtatta ctggagattg
    17401 aaatgcaagg agcaaaacaa ataaaagaag tttgcccaga gggagtattt atatttgtac
    17461 taccaccatc acttgaagaa ttaaaaaata gaattgttgg aagaggtaca gaaacagaag
    17521 ctgaaataga gaagagattt agctgtgcat atgaagaaat taaaatgatt aaggattatg
    17581 attattttat atttaatgaa gatgtaaaaa catctgctaa agaaatagaa ggtataatat
    17641 catctgaaaa gaataaagtt agcagatata aaaatattat aatagagaaa tttaaggagg
    17701 aattataatt atgttaaaac catctatcaa tgaggtacta gaaaaaatag acaacagata
    17761 ctatttagta gggactgttt caaagagagc aagaaaatta attgatggag aagaaccata
    17821 tgtttcaaat aaaactaagg aaaagcctgt atgtgtagca actaaagaag ttgcaagtgg
    17881 aaaaataaca tatagattat tgacagaaga ggaaatagag atagaagaag ctagacatca
    17941 tgctgagcaa caccaacaaa tttcagaaga ggagtaaggt catgctaaaa gataaaactg
    18001 ttgtaattgg cataagtggc ggtatagctg catataaggc ttgtgatgtt gtaagtaagt
    18061 taaaaaaact aaatgcaaat atccatgtta taatgacaaa atcagcaaca gaatttgtta
    18121 aaccacttgc atttcaatcg ctgagtcaaa attatgtagt agaagatatg tttgaagaac
    18181 caaaaacttg ggaagttgaa catatatcat tagcaaaaaa agcagattta ttcttaatag
    18241 ttccagcaag tgcaaatgtt ataggcaaga ttgcaaatgg tatagctgac gatatgttga
    18301 caactactgt tatggcaacc aaagcacagg ttcttatagc accagctatg aatactaata
    18361 tgtatgaaaa tccaattgtt caaaaaaata tacaaacttt aaagagcttt ggatataaat
    18421 ttattgaacc agaaagtggg aggcttgcat gtggagatat tggaacaggc aaattagcta
    18481 atccagacat aatagtagag gaagttttga ctaatcttac taaagagcaa gatttaaaag
    18541 gtcaaagtat gatagttaca gctggtccaa ctgtagagag tatagaccca gtaagatatt
    18601 taactaatag gtcttctggt aaaatgggat attctatagc aagagaagct atagctagag
    18661 gtgctgatgt aacattaata tcaggtccta caaatctttc tattccacaa aatcttaaaa
    18721 aatttgttca aatagagtca gcacaagatt tgtatgaagc agtagtatca aatttaagtg
    18781 aaaataaaat agtaattcaa agtgcagcag ttgcagatta taaaccaaaa acttattctg
    18841 acaaaaaaat taaaaagaag aatgatgatt tatcaataga actaagtaga aattatgata
    18901 ttgcttatga aataggaaaa ataaaagaag ataagatact aattggattt gcagctgaaa
    18961 ctaatgacct tatagaacat gccaaaggaa aaataaaaaa gaaaaattta gattttattg
    19021 tggcaaatga tttaactaaa gaaggtgctg gttttagagc tgatactaat attgtaaaaa
    19081 taatagatgt agagggaaat attactgagt atcctaagat gaaaaaagaa gaagtagcca
    19141 atgttatttt agataaagtt aaagcgttgc ttgagaaata agaccttttt taaatatgat
    19201 atttgtgtat tttatcacag ctaaagtggc tgaaagctgc aatttaattt tagcgagtaa
    19261 aaactcgcaa atgtcagtta aattgtagtt ttcagcattt attttgtcat aaagtataaa
    19321 atataattaa tagttaatta ttaaaataaa gttaatatta ataacttgaa attgcttata
    19381 aattctgaga ttttaatatc ttgtaaagta tattaaaata tgaacaatat attaaattta
    19441 agtagaggtt ttataatgaa aaaatatgca aaggtaatag ttagaagtaa tactatatat
    19501 acagataatt tatttacata tcaaattcct gtatttttat ctgatgtaat aaaaatcggg
    19561 cacagaatat tagtaccatt tggaaaaggt aataaaccaa cagaagcctt tgtatttcaa
    19621 tttacagata gcttagatga aaaaataaaa ataaaagaaa ttattgatat attagatgaa
    19681 aatccaatat ttagaaaaga agatttagag ttggtttatt ggatgaaaaa tagatatttg
    19741 tgtacttata tagaatgtat aaatttgata tatccaaagg gatacaaatt aaataattat
    19801 aaagtagtcc tattaggtga aagtttaagt ggattaaatg agattgaatt gaaggaaaaa
    19861 atatcaactt taagtgataa aaatagagaa atagtagaga aagtgattga tagtaaaggt
    19921 aaaattaagg ttgataagtt aaaatatata ccaaacttaa atagttcttt gtacacaatg
    19981 aataaaaatg gaattataaa attatgttgg gaatataaaa atcacaaaaa tgaaaagaaa
    20041 gtatgttata tatctttgag tttagaaagt gataagattg acgattatat agagcaaaat
    20101 aaaataaatg tgggaagtaa acaaaaagag atattaagtt ttcttaaaaa taatgaaaat
    20161 gtagagataa atgatttatt ggatttatta aatgcttcaa aacaaagtat aaattctcta
    20221 agtaagaaaa agctaataac cctagaattt aaggattatt atagagagcc aaaaagtatt
    20281 tacaaatccg tactaaaaag tataaaatta aacaatgaac aacaagaagc agttgatgag
    20341 ataaagtcga atatgtttgt agatgataaa aaaccatact taattcatgg agtaactgga
    20401 agtggaaaaa ctgaagttta catggaaata atagaatttg ctctaaatca aggcttagac
    20461 agtatattct tagtacctga gatagcatta actcctcaaa caatagatag gctaaagagt
    20521 aggtttggag atttagttgg agtgttccac agtaaactat ctgaaggaga aaaacatgat
    20581 gtttacaaag ctgtcaaagc aggtaaagta agagtgttaa ttggagctag gtcagcttta
    20641 tttgcacctt ttaattcctt aggcttaata ataattgatg aatgtcatga gtcatcatat
    20701 aagtctgaga agaatccaaa atttaatgct atagaagttg ctagatttat ggcattaaaa
    20761 aataatataa ctcttatttt aggttcagca acgccctcaa ttgaagagta ttatagggca
    20821 aaatctggag aatacaaact tataaatata aaaagtagag caaatgataa gcctcttcca
    20881 aacattgaag tggtagacat gaaagatgaa ttagataaag gaaatagaag tatatttagt
    20941 ttgaaattac aaaaagaaat acgttatgcg attgaagaaa ataatcaagt gatactattt
    21001 ttaaacagaa gaggttatgc aaattttgta tcttgtagaa agtgtggata tgtgtttcaa
    21061 tgtgaaaatt gtgatatatc tttaacttat cataagaaaa gcaatactgg aagatgccac
    21121 tattgtggat atgagaaaga aattccaaaa gagtgtcctg aatgtaaaag tacttatgtt
    21181 aagccatttg gagttggaac tcaaaaaatt gaagaggaat taaaatatat ttttccagat
    21241 ataaaaactt tgagaatgga taaagataca acttcaaaaa aaggtgcttt agatgagata
    21301 ctaaataaat ttaaagataa agaagcagat gtacttattg gaacacagat gttaagtaaa
    21361 gggctggatt ttgagaatgt aactttagta ggtattttgt ctgcagacat gatattaaat
    21421 tttccagact ttaaaagttt tgaaactaca tttcaattga taactcaagt ctctggaaga
    21481 gcagggagag ctgataaaga gggaaaagta gtacttcaga cttatgacac tgaacactat
    21541 gctattaagc atgctattga atatgattat gagggttttt atgaagatga gataaaaata
    21601 agaaaagcat ttggatattc tccttttaat aatatgttaa gtgtagttgt tagtggtgaa
    21661 gatgaaagat tagtgataaa aaatataaaa aatatgcatg catcattgat ttatttatta
    21721 gaaaaaaggg gtataaatga tttaggattt atattaggtc caaatccatg ttcaatatca
    21781 aaaataaatc aaaattatag atggcaaata ctctttaaag atgaaaatat tgaaattaat
    21841 ctcttaaagg gtataataaa atatatatgt ataacaaaac gagatttgat atttgataag
    21901 aatatcaatg tatctataga tattaatcca aacagtgtat tataaattta ggaggaatta
    21961 taatggcttt aagacaaata gttcaaatag gagaaccagt attaagaaaa aaatcaaaaa
    22021 aggttgaaaa aattgatgaa aagataatac aattattaga tgatatggca gaaactatgt
    22081 atgatgcaga tggtgttgga ctggctgcac ctcaagttgg aatattaaaa agagtagtag
    22141 taatagatat tggagaagag cttatagaac ttataaatcc tgaaataata gaaacatctg
    22201 gggagcaaat agatgaggaa ggatgtttaa gtgttgttgg agaagctgga aatgttagaa
    22261 gaccaaatta tgtaaaggtc agagctttaa atagaaatgg cgaaacaata gagttagagg
    22321 gagaagaact tttagctaga gcattttgtc atgagataga ccacttagat ggaattttat
    22381 ttgttgacaa aatagaaaag tagtaggagt tgatttgatg aaaatagtat ttatgggaac
    22441 tcctgatata gcagttccat gtttacaaaa aataatagat gagaagtatg aaatattggg
    22501 tgttgtaact caaccagata aaccaaaagg aagaggtaaa aaactaggta tgagtccagt
    22561 aaaagaactg gcaattgaaa ataatatacc tgtatatcaa ccagtaaagg ctagagataa
    22621 agaatttata gataaaatta aatctttaaa tccagatgta atagtagttg tagcttttgg
    22681 acagatactt ccaaaagaaa tattagagat tcctaaactt ggatgtataa atgttcatgt
    22741 ttctttactt ccaaaatata gaggtgcggc acctataaat tgggtaataa taaatggtga
    22801 agaaaagact ggtgttacaa ctatgtatat ggatgaaggg ttagatactg gagatatgat
    22861 actaaagaca gaagtaaatc ttgatgaaaa tataacagca ggagaacttc atgataaaat
    22921 gatgaatata ggagcagaaa ctttaaaaga aacattaaga ttaattgaag aaggaaatgc
    22981 tccaagagaa gtacaaaatc atgaagaatt ttcctatgcg ccaataatga ataaatcatt
    23041 aggtaacata gatttttcaa aaagtgccag agaaatacac aatttagtta gaggagtaaa
    23101 tccatggcca agtgcttata ctatctataa tgatgtcata atgaaagttt ggaaaactaa
    23161 agtgttagat gaaaaaagca caaaagatgt aggtacaata attgatgtaa gcaaagatgg
    23221 gataaaagta agtactatag ataatgtact tttaattgaa gaaattcaga tgccgaataa
    23281 aaagagaatg ttggttggtg aatatataaa agggaatact atagaaactg gtttagtatt
    23341 gggttaggtg aaaagtatga cagatataaa gaagtattta acaagtgttg ggattttgat
    23401 tttaatatta ggaattttga taggagttgt taattttttt ataataagtt taactcaaat
    23461 attctccttg atgataaata ttataataat atcactaata cttataatac tatgttcaac
    23521 agcagttact tatagagtaa ttaaaggaaa gtatgttaac tcaaatataa tgaaaataaa
    23581 ttttaatatt gtcagtggat tatttcctat tatatctttc attgcatcat catttggtat
    23641 gtcaaaaagt gatattagaa gaatatatat aaagttaaat aatgaatata tatacagtaa
    23701 taaatataat tttaatccag aggatataat aattttaata cctcattgta ttcaagagaa
    23761 tagttgtaaa ttaaaagtta ctaatgatat agataattgt aaagaatgtg gaagatgcaa
    23821 cgtaggagaa ttaattaagc taaaggaaaa aactaatgta aaaatatttg tagctacagg
    23881 aggaacccta gctagaaaaa ttataatgga taataaacct aaagctgttg tagctgttgc
    23941 atgtgaaaga gatttgacat ctggaataca agatattaag aaaattcctg ttttaggtgt
    24001 atttaacaaa agacctaatg gaccttgtgt aaatactaat gtagacatga tggatattga
    24061 aaaagctata gactttttaa caggaaaaaa tatattaatt tgtaattaaa ctgtttttaa
    24121 gttaagtgaa tattaagagg atgtataata aaaatatatt ttaggagagt gttatttatg
    24181 taccctgtat atggcggttt ttggggattt gacccaacaa tggttgtatt aattccagct
    24241 atattactta ctatatatgc acaatttaaa gtgagttcaa caacaaataa gtatttaaga
    24301 gtaaatacac gtcgaggata tactggagag caaacagcaa gaagagtact tgattcaaat
    24361 ggtttgtatg atgtaaagat agaaatggtt agagggcatc taagtgacca ttatgaccca
    24421 agaagaaagg ctgtaaggtt gtcagaagat gtatattatg gaacatctat aacttctgtt
    24481 gcagtagctg cacatgagtg tggtcatgcc atacaacatg ctaaaggtta tgcgcctctt
    24541 caaataagaa gtagtttagt accagtagtg aattttgctt caagtatatc ttggttttta
    24601 atatttttag gatttattat ggctggtcca tttttaaaaa ttggtatact attgttttcg
    24661 gcttcagtgt tattccaaat aataacattg cctgtagaat ttaatgcttc aagtagagca
    24721 atcgttcaac ttgggaattt aggtattata gatgaaagtg agtcaagaca aagtagaaga
    24781 gtactttcag cagcagcttt aacatatgtt gcagcagcat tggtttcaat acttcaatta
    24841 cttagattgt tactaatagc tcaaagaaga aatgactaaa agtaaagtgg gttgtttaga
    24901 aacaaccctt ttttatgttt aataaaaggg agaaatttat atggatgcaa gagaagttgg
    24961 atttaaagta ttatgtgata tagaaaaaaa tgacaattat tcaaatattg caataaataa
    25021 gcattttaaa aatttagaaa taagtgatat ggatagagga cttgcaacag agttaattta
    25081 tggagtaata gaaaataaat attatttaga ttatataatc aataaacttt caaaaataaa
    25141 ggtaaaaaaa atgtcaactt atgttaaaat ctttttaaga atgggaacat atcagatttt
    25201 atttttagat agtatatcag attatgcagc agttaatgaa actgtaaaat tatctaagaa
    25261 atatgataaa aaatcttctg gtttcataaa tgctattctt agaaatgaaa taagagctaa
    25321 agagactata atggacataa ctgaggaaga tagtgtaaaa tacttatcta taaagtattc
    25381 ctataactct tggattataa aaaactggat agataaattt ggacaagaat ttgctgaaga
    25441 tttgttggaa gcaaataatg aaaagcctag tatctatata agaacgaata cacttaaaat
    25501 aagtagagaa gaacttattg aaaaattaag tgaaatgggt attgtatgtt taaaagttcc
    25561 tatggtagaa gaagctatta aagtcgaaaa aatgaaaaat atagaaaaaa atgaattatt
    25621 taaggctggt ttatttacaa ttcaagatat aagttctatg atagtaggga aagtaattaa
    25681 tccaaaagaa ggttcatttg ttttggatgt atgtagtgct cctggaggga aatctactca
    25741 cttagctact ttaatgaaca atacgggtca agtagtagct agagatattt ttgagcataa
    25801 actaaagctt ataaactcta ctgtaaatag attggggctt aaaaatgtgt ttgtagaaag
    25861 atttgatgct tctgagattg atgaaaatag tataagtaaa tttgattatg ttttagcaga
    25921 tgttccttgc tctggttttg gtataataag acgtaaacca gaaattaagt ataagaaaga
    25981 agaagagtta aaagacatca cttctataca aaagaaaatt ttagaaaatg catctaaata
    26041 tgtcaaagtt ggtggaactt tagtatatag tacatgtaca attcaagatg tggagaatat
    26101 aaatatagtt acttcttttg ttgaagaaaa tcacaacttt gaatttgttc caattgatac
    26161 agtaaatgta gacttagaca atcaagataa aggatattta aagatatatc ctaatattca
    26221 tggtatagat ggttttttca tagcaaaatt aaagagaata aggtagtgag agaatggaaa
    26281 agaaaaagat agtattaaaa aattttactg aagatgaact taaagaattt atgaaaacta
    26341 tagatgaaaa gccctttaga ggaagtcaaa tattctcttg gatatataag ggtgcaaaaa
    26401 cttttgatga tatgaacaat ataccaaaaa gtttgagaaa taaattagaa gaggtttcat
    26461 gtatagggaa tatagatata gaattaaagt tagaatctaa ggtagataat acaaaaaaat
    26521 atttgttttt attagatgat ggaaatataa tagaaactgt gatgatggat tatgatagta
    26581 gagttactgt ctgtgtttct aaccaagtag gttgtaggat gggatgtaat ttttgtgcat
    26641 ctacaatgga tggattaatt agaaacttag agccatggga aattttagac caagttatta
    26701 aaattcaaga agatactggt aagagggtat caaatcttgt attgatgggg agtggtgagc
    26761 cacttgataa ctttgaaaat acaaaacaat tcttaaaaat aattaacgaa aaaaatggtc
    26821 ttaatatagg gtatagacat ataactcttt caacttgtgg aatagtacct aaaatgtatg
    26881 agttggcaga cttagaaata gctataaatt tagctttatc acttcattca ccatatgatg
    26941 aagaacgaag aaaaattatg cctgtagcaa atgcttattc tattgaagaa atattgaatg
    27001 catgtagata ttatataaaa aagacaaata gaagggttac atttgaatat tctcttataa
    27061 aaggagtaaa tgactcagaa aaagaagcaa aggcattagc taagctccta aaaggtatgc
    27121 tatgtcatgt aaatttaatt ccaataaata aagttgaaga aagagaatac gaaaagccag
    27181 ataaagcatt tatttataaa tttagggata gtttggagaa gaacaatata cctgccacag
    27241 ttaggatgtc tatgggttct gatattagtg gagcttgtgg tcaattgaga agaaaataca
    27301 agtaatttgt aaggaggaag tcgtatggtt tatagttgtg cctcccatat aggaaaaata
    27361 agaaaaaaca atgaagacta ttgtgaggga gaagttatag atacagaaca tggtccaata
    27421 ggaatatttg ccatagctga tggaatgggt ggacataaaa aaggtgaagt cgccagtaaa
    27481 ttagcagtag aaaatataat tgattttcta aaggaaaact tattacaaca tgataatgta
    27541 aaaatagact atatagatga tatattaaaa caggcttata ataatgtaaa ctcaattgtg
    27601 cacaaaaaat ctatggaaga tatagaattt gaaggaatgg gaactacatt agttacggct
    27661 atagtgtata ataatgtctt atatgtggca aatgttggag atagcagatg ttatttgtta
    27721 acagatgaaa aatttgataa aataactata gaccattccg tggttgaaga acttatgatg
    27781 gcccatgtca ttacagaaga agaggcaaga agacatccac agagaaatag aataactaga
    27841 gcaattggaa cagatgatat ggttgttgta gatattttta agaaagaaat caaaaaaagt
    27901 gatataatac ttcttgcgac agatggatta actgggttta ttgatgatga agatataaga
    27961 gatttaatat tagattatga atatgagaga actagtaata taagtgaaga attgataagt
    28021 atggccaatg atgtttctgg taaagataat gtttcggtta tagtgataaa agtataatta
    28081 ggacggtgat attgtgggag atacaatttt aggaaatcga tatgaaatca tcaggaagat
    28141 tggtgatgga ggaatggcct ttgtatatga ggctaaagac agattattaa acaggactgt
    28201 tgcacttaaa gtacttagac ctgaatttgt agatgatgat gaatttctaa caaagtttaa
    28261 aagagaggca gaagcagtag caagtctttc acatccaaat atagtaaatg tttatgatgt
    28321 tggtgaagat ggaaaagttc actacattgt aatggagttt gtagatggga agaatctaaa
    28381 agagattata caagatgaag gtatattaga tgaatatact gcattagata taacaaaaca
    28441 aatagctatg gcacttagtg cagcgcacaa aaaggggatt atacatagag atataaaacc
    28501 tcataatatt ctcatatcaa atgaaggaag agtagtaaaa gtggctgatt ttggtatagc
    28561 caaagctgtt tcaaattcaa caatgactaa tattggtagt ataataggtt cagtgcatta
    28621 tttttcacca gagcaagcta aaggtaaatt tgtaactaat aatgctgacc tgtattctct
    28681 aggtatagtt ttatatgaaa tgttgatagg aaaagttcca tttaggggag atagtccaat
    28741 ttctatagca cttcaacaca ttaatgatga tatagacttt acatcagaag aaaaagttag
    28801 gattcctcaa agtgtaagaa ctacaataaa aaagcttaca gaaaaatcta gcgcagatag
    28861 atatcaaact gctgaagaat tgatagaaga tatagagtat atagaaaaaa atattgattt
    28921 agattttata aaagaatatg atgattttgc aactaagaaa attgatgaaa aagaaattaa
    28981 taaagttgta aatccaacac ttgcaaaacc agctcctgaa aaagtggtta agcctgttga
    29041 agtagctgat ttggatgatg atgaagatta ctatgatgat ttttatgaag aagatgaaga
    29101 agaagaagaa gaagaggaag agataatgag agctaaaaag aatcagagac ctaagagtac
    29161 tccaagtaag agaactaaga aaaagaagaa aaaacaggaa agcccaaaat ctagaagaag
    29221 attaaaagta attgcggctg ttttgatact gatattgtgt gctcaagtat tcttagcata
    29281 taagttttta tttgctggag ggtttggcaa taaatctttg actgttccta atcttgtaaa
    29341 tatgacatta gaagaagctc aaagtgctgt tgaaaaagaa ggattatacc tgagtgtaaa
    29401 aagtgaagag tataatagtg aagttgatga aaattgtata atatcacaga cacctgaagg
    29461 tggaagtaca aatgtcaaaa agggtgatac tataaatgtt gtcgtaagta aaggttcaag
    29521 tcaggcatct gttcctaatg tggtgggact tactttgagt aatgcaaaac aacttattga
    29581 agaaaataac ttaaaagtgg gaactgttaa gtatgaatat agctcaatat ataaagaagg
    29641 tacagtttta agtcagagtc caggtgctgg ctcatcaaga gctcaggaag gtgatgaggt
    29701 aaacctatat gtaagcaaag gttcagaaaa atcaaataca cagactccaa cagtaccaga
    29761 taaaaaacca acaacaccag agaataatac accaacagaa cctggttcaa actcagggaa
    29821 cagtggtgga aattcaggaa gttcaaactc aggaaatagt ggaggaaact caggcaataa
    29881 tggaggtaac tcaggaggtt caaactcagg aaatagtgga ggaagctcag gaggctcaaa
    29941 ctcaggagat aatggaggaa gttcaggagg ttcaaactca ggagataatg gaggaagttc
    30001 aggaggttca aactcaggag acaatggaga tagttcagga ggctcaaact caggagataa
    30061 tggaggaact tcatcaggaa ctggcgcaaa cattggtaaa acagaataaa tattaataaa
    30121 ataagagctg tccttttata gaaaatattt tctttaaagg gcagtttgtt ttgtataaaa
    30181 tactgaattg gttataatat aaggagaaaa gtatttatga agaagaaaac cgttttaatt
    30241 acaggaggag ctagagggat tggtaaagct atgtctaaag cttttgcaaa agaaggttac
    30301 aatgtattag taaattttaa taagtcagaa aatgaagcta aagagttgta tactatatta
    30361 aatgaaaaaa atttttctgt aaaacttttt aaggctgata tttcaaatag agaagatgta
    30421 gagaatatgg tagattattg tataaaagaa tttggaggat tggatgtact tgtaaacaat
    30481 gctggtgtaa gtcaagataa gttgtttaca gatataaccg atgaagattg ggataatatg
    30541 atgaatatta atttaaaagg aagcttttat tgttcgcaag ttgctttaaa atacatgata
    30601 tcagaaaaaa aaggaaatat aattaatata tcttcaatct ggggtatatc aggtgcgtct
    30661 tgtgaagtgc attattctat aacaaaagca ggtataatag gtatgacaaa ggcattagct
    30721 aaagaagtag gaccatcaaa tattagagta aatagcatag ctccaggtgt cattaatact
    30781 gacatgttat ctggatataa tgaggaagat atagacgctc ttgtggaaga aacccctcta
    30841 atgaggctag gaactccaga agatatagca aattgtgcta ttttcttggc atcagacaaa
    30901 tcaaatttta tcactggtca ggtaattagt ccaaacggag gatttgttat ttaaaaaaaa
    30961 tgtggtatta tataaaaata ggaaagaata acacgatata ctattcataa acagtatgtg
    31021 tttatataaa ttttataaag ggaggcattt gatgctagaa ggaaaaatta taaaggggat
    31081 tagtggattt tattatgtag atacttataa tggtatttat gaatgtaagg ctagagggat
    31141 atttagaaag cagaaaataa cacctttggt tggtgataga gtcaaaataa gcattgttga
    31201 tgaagatgaa aaaaagggta tcttagaaga aatcgacagt agagatacag aacttataag
    31261 acctcctatt gcaaatgtag ataaagcatt aatagtattc gcaataaaaa atcctaaacc
    31321 aaacttatct cttttagata gatttatagt tttggcagaa aaagaaaatt tagaaactgt
    31381 aataatcctt acaaaagcag atttagatga taatgataca ttagaaactg ttaaaaatat
    31441 atatgaactt agtggctata aagtcattcc tgtaagcaat attactaagt taaatataga
    31501 taaagtaaaa gaagaattaa aagaaaatgt agtagtgttt gcaggaccat ctggagttgg
    31561 aaaatcaagc ttattaaatg aaatagatga aaattttaaa cttcaaacag gagtggtaag
    31621 tgataaaata aaaaggggaa aacatactac tcgtcacgct gaacttttaa aattggaatt
    31681 tggtggaatg gttgcagata caccaggttt tagttccctt gcacttgaag atatagagga
    31741 agttgaactt aaagattatt ttatagaatt tgataaattt aatgattgta agtttggttc
    31801 aaagtgtatt catgaaaatg aacctaattg tgctataaaa gaagctgtta caaatggaga
    31861 aatatctaaa gaaagatatg atagttatat acagctgcta catgaaataa gacaaaataa
    31921 tagtaggagg tattagaaaa atgattaaat tagcaccatc aatattatca gcagattttg
    31981 caaaattatt agaagatgta agaaaagtag aaagtgcagg atgtgaatat cttcatatcg
    32041 atgtaatgga tggacacttt gtaccaaaca ttacattagg accacttgta gtcaaaagtt
    32101 taaagaaaga aaatataaat atggtatttg atgctcatct tatgatagaa aatccagacc
    32161 agtatattga agaatttgta aaagcaggat gtgatataat aactgttcac caggaggctt
    32221 gtgttcatct acatagaact atacaaaata taaaatcaca tggaataaaa gctggtgtag
    32281 tacttaatcc agctacacca gtagatacga ttaaacatgt actacctgat ttagatatgg
    32341 tattattaat gtctgttaac cctggatttg gaggacaatc atttattcct tgtgttttag
    32401 ataagattaa agagttaaaa gctattatag atagtcaagg attaaacatt gatatagaag
    32461 ttgatggtgg tataagccct aaaaacgtag ccgaagttgt acaagcagga gctaatgtaa
    32521 tagtagcagg ttctgcaata tttggaagtg atgacattca agaaacagtt aatttattta
    32581 gaaagaatgc ttctcttgaa gaattagttt aaatttaata atgaaaatct gtattgtttt
    32641 aaatggcgaa attgaagatt acgaagttac aagagatatt ataattaagg aatgttatga
    32701 ctgcataata tgtgcagatg gaggggcaaa tcacacttat aaaatggaaa taatgccaga
    32761 ttatatatta ggagatttag attcagtaga agaagaaaag ataaacttct ataaaaataa
    32821 aggtgttaaa tttgaaaaat ttccatctaa aaaagatgag actgatacag agctttgtct
    32881 ttttttagct aagacactta aagcaaatca tattgatttt tttggtgctt tagggggaag
    32941 gattgaccac actcttgcaa atataaagct attatattat ttaaaagaag atggtatata
    33001 ttctaggata ctttctgata aagaagagat gtatatagtt gaaaatgagg aaatttcatt
    33061 gtatggaaac ccaggggaca ctgtttctgt aacagctata aaaggtgatg ctaagggtgt
    33121 aacacttact ggcttagaat accctctcga taattattat atgaaatact ctgtacctat
    33181 tggaatatca aatgttatgt tgagtaattc ttgtaagatt aaagtagagc aaggctgtgt
    33241 acttgtagtt agaaatttat aaaatttgat tttgacaatt ggttttatat tgtagagcag
    33301 atacaatcaa gtaaaatata tttatgattg tatctgcttt ttagtatata attataaata
    33361 tataataaac tttgacataa gggggatttt ttgtggtaga tagtattatt tttgatttag
    33421 atggaacatt gtgggattca actgaagaag tatgcaaagt ctggcaggat gttttaagta
    33481 aacataagga aatagaatta agtgtcacaa aagatttatt tagaagtctt atggggcttt
    33541 cttttgagga aatagcaaat cgtttatttc caaatttaag tgaagaagaa agaatgaatt
    33601 tattgaatga atgttctttg aaagaatgtg actatttatc tgaaaatgga gctaaattat
    33661 ttgatgatat agaagatact cttaaattac tatctaaaaa atataaatta tttatagtaa
    33721 gtaattgtca agctggatat atagaatctt ttttaaaagc acataaacta gaacagtatt
    33781 ttatagattt tgaatgtcct ggtaatactg gtttgcataa aggagaaaat aataaactta
    33841 taattgaaag aaataaatta ataaatccaa tctatgttgg tgatacgcaa ggtgatgcaa
    33901 atagtgctaa gtttgtaggt atacctttta tatatgccaa atatgggttt gggaatgtag
    33961 atgtatatga ttattttata gattcattta aagatttgtt agaacatgat atattaaaat
    34021 aagatgagtt taaaaattat attaaaataa taaaaaagtt atggggggat ttaaaaatgg
    34081 aattacaaga tactattttt aaaagacaaa gtgtaagaaa gtttaaaaat caagatgtat
    34141 cagatgaaga tattttaaaa atgataaaag cagcaggtgc agcaccatca ggcaagaata
    34201 ttcaaaactg gcattttgtt gttataaaac gccgtgattt aatggaaaag atagcagatg
    34261 tgataactaa aaagcaacaa gaaatacttg tggaaatgga taaagtatca gtggataagg
    34321 ctaatagatt tagaaaattt gttaaaaact ttacactatt ttacttaaaa gctccagttt
    34381 tagtattagt ttttacaaag gtatataatc catcaggata ttatgaatta gagcttatag
    34441 atgcacctaa ggagactata gataaattat ttataagaaa tccaggtatg cagagtctag
    34501 gtgcttcaat tgaaaacttt acactatcag caattgaact tggatatggt tcttgttggt
    34561 tgacaagtca aaactatgca gcagatgaga tagaagctgt tttagaagca gaaactggtt
    34621 ttgaaaaggg agagtatttt ttaggtgcaa tgttagctct tggagtgcca gaggacaatt
    34681 tgaagagtcc atctaaaaaa ccagtagaag aaatatgtac atttataaaa taaaagtcaa
    34741 ggacatttta aaatcaaagt aaattaaaaa caagataaat taaaaataaa tatttaaaaa
    34801 attaaaaagt aggttttatt gatattaatt ttatatttca aatcattgat ttaattaata
    34861 caataagaac tacttttttt tatatattaa ttctaaatat atttaaatct ttagaaaatc
    34921 tttagaaaag tatatgtaat atcttaagtt tttaatttta atattaagta tataaaacaa
    34981 aatgaaaaaa tattaagttt aaactagaag gaggtttcta agatggacat taaatacaaa
    35041 taaccagaac aaaagatata aatatatata taaatggaaa aacttctatc atattgtata
    35101 atcatatatg taaagaaaat ttataaatta atataaagga gattaaaatg aattcatata
    35161 atattttggt ggtagaagat gaaaaggaga tcgcagatgc tatagagata tatctattaa
    35221 atcaaggata taatgttttt aagggataca atggattaga aggtcttaag gttatagaaa
    35281 accaagaaat acatttagct atagttgata taatgatgcc taaaatggat ggtataacac
    35341 ttacaatgag gcttagagaa aactataatt ttccagtaat aatgctatct gcaaaatcag
    35401 aagaagttga caaaataatg gggcttaata taggagcaga cgattatgta acaaaacctt
    35461 ttaagccatt agaactattg gctagagtta attcacaact tagaaggtac actaagtatc
    35521 taaacatggt tggaaataaa gagcaaaagg tagaaagtga tgatagtgtg tttgcaatag
    35581 gcggattaga attaaatgaa aatacaaaag aagttaatat tgatggaaaa tatataaaaa
    35641 caactcctat agaatttaaa atactaagtt tacttatgag aaatgcagga agagtttttt
    35701 ctgctgatga aatatatgaa agagtttgga atgaaaatgc tataaataca gatacagtta
    35761 tggtacatgt gaggaatata agggaaaaga tagaaattga cccaaaaaat cctaaatatt
    35821 taaaggtggt gtggggtgtt ggatacaaaa ttgaaaaaat ttaaagataa atatatagtt
    35881 actattatag tttttatact tatgttatca gcatcattag gtatgattag tcaatattct
    35941 actatacaag caggtgctaa aggtggagca aagaatccat ttgaacagga aagctttgta
    36001 gatagtatat ataaaggaag ttatgtttta tatcataata tgaaggaaga acaagaaggt
    36061 aagatgatac aaccatcaaa gctatttatc aatgaagaaa ctatgaacta tataaaaaat
    36121 gtaagtaaag aaaaagatac ttatgatggt tcagaaactt attatacaga tgatagtatt
    36181 aatgcagatt ttaatgaaaa ctttgaaaat tgggagcatt tcattaaagc gtcaggaaag
    36241 aatttaaagt actatttagt tgataaagaa agcaattttg aattttttaa tgataataaa
    36301 gaattaggag tacttgatac aacaaagaat gatgcttcaa aagaaaattc tgatgaaaat
    36361 cagtcaaaaa atacagaaat gaatgatgag gaaagacaaa agcagattac agatataaag
    36421 gaaaactata gattctacgt tgtaatgaat tttgataaag atggaaaagt aaatattgtg
    36481 gattcttatg gagtaaatca aaaagttatt aatcaaatgt tgttatctaa agcaagagaa
    36541 gatttaatgg atacaagttt aggaggaaat tcaatttcat ataagttatc tccaataaaa
    36601 aatataacat tagtatatgc tgtacctaaa gtaataagta aaggtgatag tgtagagtat
    36661 ggttatggaa atacttattt tgatgatggt ataatttcat atataagcaa tgtagaaaat
    36721 aattcttatt ataagatttc tggaatgatt ttaaaaatta tattagctat agttgttatt
    36781 gtagctttag cattcccata tagaaaatct aaagagttgc taggatttga tacattatta
    36841 agaataccgt tagagatact ctttattgct cttgctatta tacaggggct tgtagattta
    36901 tatcctactg ttataataag taataccttg agtgggaatt atgtagagta ccttataaac
    36961 aatgacataa gtgctaaaat ggctagcata ttggtaagtt taatgaattt aacttattgg
    37021 tttgtaatat tctcaataat atttgtattt ataatacttt taaaacatat tttaaatgtt
    37081 ggaataagag agtattttac aaaacatact gtgacaggaa tgttttttgt atggttaaaa
    37141 aaagcaggaa aaacagttat taatcaaatt agaacaataa atctaaaaga aaagccaaat
    37201 aaaactatag ttacaatttt gggaataaat ttattgatta tagttataat gtgtagtatg
    37261 tggttctttg gaataatact cgcattaata tattcagtag tattatttaa gatactgtca
    37321 gattactcta aaaagacaat atatgaatat aatcaacttt tagatgttac aaagaaaatt
    37381 tcagatggaa acttagatgt aaatatggaa aaagatttag gattttttaa tcctataaaa
    37441 gacgaattag gaaatattca aactggattt aaaaaagctg ttgacgaaga ggttaagagt
    37501 caaaagatga aaacagagct tatatcaaat gtatcacatg acttaaaaac acctctaaca
    37561 tctataatca cttatataga tttattaaaa gatgaaagta taacagatga aaatcgtaag
    37621 ttgtatattg atacattaga cagaaagtca caaagattgc aacatctaat agaagatttg
    37681 tttgaagtaa gcaaggcaaa tagtggagat gtttatttga atatagtaaa tgtggatatt
    37741 gtatctctaa tgaagcagac acttttagaa ttagatgaca aacttgcaga ttcatctcta
    37801 atagtaaaga ataacttttc taatgaaaaa ataatattac cattagatag tcagcgtaca
    37861 tttagagtat ttgaaaatct tataataaat ataagcaaat atgcaatgcc aaattcaaga
    37921 gtgtatattg atattttaga aacagataat aaagtaaata ttatgcttaa aaatatgtct
    37981 gcatctgaga ttgattttag tgtagatgat ataatggaga gatttgtaag aggagataaa
    38041 tcacgtaaca cagaaggttc tggtcttggt ttagcaatag caaaaagttt tatagaatta
    38101 cagggtggta agatgaatat aagtgtggat ggtgatttat ttaaagttac aattactttt
    38161 aacaaaaatt agattagact tctttaataa ttataaagtc tatagaataa aagagtctgg
    38221 aaatatttat gtgtattctt taaataaaaa tttataggta ttgttttaaa ataatttgta
    38281 agtattattt caaaacagct tataaatgtt attttaaaac agaatgttga tttatttaaa
    38341 aaaggtgaat cctaatatac aaggttcacc tttttatttt acaaaatgtt atttagtgtt
    38401 acagagctta taaatagcat aatatctggg tttactatta acatagtact agcaatttat
    38461 tttgaaatct tgtataagct attttatatt atttaattac tattgtttgt actttacaat
    38521 gtgataaaga atttacctct acagttttag tatttacttt aagcttgcta ttattatcat
    38581 agatttcgtc gagcattgca ctataagcat cattgacatt tttattgatg ttaagacttc
    38641 ccttagcatc ctcatttttc ataccattga agattctaac tacaattcca tctccttttt
    38701 cttctttctt tattgcactt actgtgaaat ttgaattatt tacattcatc aaactaaatt
    38761 cattttcata tatttgtttt tcgtcattga atgcaaatag aagtctacca tttaaaaaat
    38821 cagcatattc atatatttgt ataggtgtta agaatctctt agctgtatta gctacatttg
    38881 cttcatcaaa tttattgtta tatatgtaaa gaccaaagtc aaagtttaac tctttaagta
    38941 attgtgcatc tggtgttgct attatttttt ctccagaagc tcttcctggt ctataaagta
    39001 aattttctct tcccatatat ccaaatgacc tgaatagtgt taatgctatt gtatctaaat
    39061 tatcaccaac tatttgatat tctcttacac aaccagttat taatgctatt cctctttgtc
    39121 catcctctaa agtaacaaaa ctttgcattg gttcgatagt tataggtttt tcttgccatg
    39181 agtaattgtc tcttttccat aatgcaaggt ctttttctaa tactgttggt ctttgtatta
    39241 ttccaaattg ttgatctgct atagaaaact tagatgctat ttctgtatta aataaaactc
    39301 ttactctatg agatagtgct tggttatttt ttatattaac attaaactta attatttgtt
    39361 ctttaggttc taaggtaatt ttcattgtta ctggcatttt cacagaaact ttacctatag
    39421 acctttcttc cagtgaagct ggtatggtca atgaatattt aagtatcatt tcttcttgaa
    39481 tatttgattt tagcacttct actgaagata cagaatctaa agatgaaaca taaatatctt
    39541 ttcttggagg agaatagttg tatgaatctc catcatctcc attgtcttca attacagctt
    39601 ggtttttata agtcttacta gattctttat ctaatatttc taatgaacca tttttattgg
    39661 ctgttatttt gtaatatttg ttttctattt ctttgcaatt acttgtttct atttcacatt
    39721 tatttttagt atccaattca aaaactagtt gagtatatcc cattggtggt atatctttta
    39781 ctgaaagtgc aatttttgct ctatatacag ttttgggtat atatattttt ttacttgggt
    39841 ttaatcttat tgtttgagtt aatatataat ttgtaatatc ttctttttct tttattatat
    39901 aattaagaat ttctccattt ttattcttta tcacaaaatc ttgacctgga atataagtgt
    39961 caaattctac aacttcattt ctgacttctg ggaatccatt gaatactgtt aatgttattt
    40021 cttcattatt atttttgatt tgagtactta taagtctcat atgcaaatct aataaattta
    40081 tactcaaatc tctggcttgt ttgtatcttg tgtatacatc ctcatttgct gtgtcactat
    40141 tacaagaacc tatgctgtca tgagctgcat tttcaaacat aagtttccat atatctttta
    40201 taactagatg agggtattca tttccaagtg aataacttaa tgttaataat ggttcaagta
    40261 catttgtgat ataattttct aatttgttat tcattatttt aaggtctgac cttgaggaga
    40321 atatggattt gtgtattctc atatgtttag catttaaaaa ttcaccttta agctctgtaa
    40381 attcatttct ttcatttttt actgaatcta tatagttttc tatattactt atttcgtatt
    40441 cattttcatt atctatttca ttagcttttt ttaatatatc aggaaggttt tttcttattg
    40501 gtgcttggtc aaatccattt ggaaaatata cgttattagt agaagcttta accttaagtt
    40561 ttccaattat atcttttaaa tattctttta aatctgaatc atcttctggt atattacctc
    40621 catagtaata accaaatggt atttgaactg ctaatacttt tgaaccatca gaacctttcc
    40681 atataaactc tgttgtatct accatatcat cagaaactcc acgccaaaat aatgaactat
    40741 ctattccaaa acctctgtat atttgtggca tttgagctga ttgcccaaaa gaatctggta
    40801 catatccaac cctcataggt tcaccaaatt cattgcatct atctattcca tagtaaaggt
    40861 ttctaattat agattctcct gatataacca attggtctgt ttgagtatac caaggtccaa
    40921 taactaatct tcttctttga actaaatctc ttattctata ttcatcctga ggtctccatt
    40981 ttaaataatc atctaagaga gaagcttgtg catccatagt aaagtattta aagtcctctt
    41041 tttcttccaa tatgtctaat atatcttgaa aatctttcat taaatatatt tttgaccttg
    41101 atgttgtaaa ataccattct ctatcccaat gactgtgtgg aactacatgt acttttgtct
    41161 ttttcataaa aatcctccca aaatttaatt gagaattgag agtacactca attctcaatt
    41221 atctaaaatt aagtttttaa tttacattat atctaactct atttcatcaa attctgtatt
    41281 ttccgtagtt tcatcttcat tgaagtctac taaagttgtt gataatattg ctattactaa
    41341 agctccaaat attgcaccta ctaagtaagc ccatccagaa cctattgata taaatccata
    41401 taatccacca actggaggca ttatagcatg tacacctaac aaagctgata atcctacacc
    41461 caaagcgcat cctatcatat taacaggaac taattttaat ggatttgtta aagtgaaagg
    41521 aattgcacct tctgttattc caattatacc cataactata ttgccttttc ctgtttcagc
    41581 taatgcattg gaaaattttg attttcttat gaatgtagct aaaccatatc ctagtggagg
    41641 tataactatt gcgcagttta ccaatatcgc tggtagatag attccctcta acaataatgc
    41701 atttcctgcc atccaagctg ctttatttac tggtccacct aaatcgaatc ctatcattgc
    41761 gcctaaaatt aaagccaata ccaccgaatt tgttccattt tgacacattt cagctaccca
    41821 agcatttaat gaagtattta tgtttcctaa aggtcctgct aatacaacac tcattaaaaa
    41881 accagttaat ccaactgtta taagtggcat tattataagt ggcatcattc ctgatgctga
    41941 cccagatatt ttaatttttt tctttaaaaa cttacaaaca tacccagcaa agaaacctgc
    42001 tattactgct cctaagaatc ctgcattagt attacttgct atgagcccac caataaaacc
    42061 tgcacccata gctggtttct cacctattga aaatgctata aatcctgcta ataccgtatt
    42121 taatagacct atgccagtcc aaccaacttg ttccattaag taaagaatat gataaaaacc
    42181 agatacattt ttataagcat ctaaacttgt tatacccatt gctaaagctg taagctttgg
    42241 gatagctaca actaaagatg agcctattac aagtggcaac atatatgaga tacctgtcat
    42301 taagtgtccc ttaagttcac ttaaaagaga tttatttttt ttactcattt ttaatcctcc
    42361 tatataagtt tgttatattt tttgataata tgttataatt acattagaca attttttaat
    42421 tttttatttt tctcattcta tattagagtg agattttttt attaagaaat agcttctata
    42481 cactttgtta agacagcttc tggttttttt aacgctatac ctattttgac ttttatcact
    42541 tttttaccat caaatctttc cattccagat atagtttggt cagatgctat aagtataaag
    42601 tccgcatctt gtgcttcttc ttttgttata gtatttactc gtcccatagc accttgttgt
    42661 tctactttga tttcatgacc catttttgat gcagcttgtt ctaaagcttt tgctgccata
    42721 ggtgtgtgtg ctaatcctgc tatacatgat gttattgcta ctattttcat aattattcct
    42781 ccttcatttt attagttata tattttacta aatgacttgc atcactagca tttttaactt
    42841 cacttgtaaa atcatcctcc attaaacatg tggctaattt agatagagtt tttaaatgta
    42901 tatttccttc atttttatgt ggggctaaca aactaaatac atatctaacc ttactatcat
    42961 ctaaagtttt ccactctaac tcgttagttg ttttaatata gagtatggaa gcttccttta
    43021 catttacact ttttgtatga ggtatcgcaa atccatcttt tattcctgtt ggaaattcat
    43081 tttctctttt tagaaggtct tttaaaagag cctctttatt agttgcaata cctagtatat
    43141 aagcactatc tgcaataaaa tttaatactt cttctttgct ttttaagtct ttatctataa
    43201 atatatattt ttcttgtagt accatatatt tttccactcc attcgtaatg tcttaactta
    43261 tatttatatt gtaatcatta tcctaattaa attaaatata actaatttcc acttcgacat
    43321 ggaaatttat attatgataa taactaattt ccatatagaa gtggaaagaa attattataa
    43381 tacaatttta ttagagtaat tgtattatat gagtgtaaat agtataattt agaagaaatt
    43441 ctataagggg ggatatttat gcacaagaga ttgctcacgt tgtttaaatt attaaatgaa
    43501 agtgatgata aaattacttg taaaacttta agtaatcatt taaaagtgag tgagagaact
    43561 ataagaaatg atattacttc tataaatgga actttagaga aaaatggtgc tattattaaa
    43621 ataaaaaaag gagaaggata ttatatagat attcttaatt tagcattata ccaacagtat
    43681 ctagcattaa tatctgatga tattatggat tcaagtgaaa taccagattc tcctatagaa
    43741 agaaatcaat atattttaaa atatattctc tataacaata catatataaa actagaagat
    43801 ttagctaata gcttgtatgt gagtaaattt acaatactaa atgacataaa aagaataaag
    43861 cctattttgt caaagtataa tttaatatta gtttctaagc catattatgg agttaaagtt
    43921 gaagggaagg aaatagatat tcgaagatgt atttctaata atatgataaa taggaatttt
    43981 gaaaactata taattggaat tacagataga gaaatagaat tatttaataa tgtagattta
    44041 atagagcttc aaagggtagt gttaagtgaa attaataaat ttaatataaa ttttctagat
    44101 tttaatctaa aaaactttat tatccattta gctattacta taagtagaat acttgatggt
    44161 tactgcttag ataatgtttt agatgttgtt ttaacagatt ttcaatcgaa tacaactgtt
    44221 gaaaatatat ttaattatat tgagagtaaa tatactataa ttatttcaaa ggcagacaga
    44281 gtttatctat ataatcattt tataactaaa agttctcttt tggataacgt ttccaatagg
    44341 gtggatacta aaattataga gtatgttgaa gaaattttag aagtaatcaa caatcaatat
    44401 acttttgacc ttagaaatga tagtgtatta tttgatgatt tagtactgca ctttaaatca
    44461 attctcaatt ctaaatctta taatttaaat aaggtgaatc cccttataaa tacaataaag
    44521 agtaattatc ctttagcatt tgaaataact ttaaatgcta tagaaaaagt ttttaaaaat
    44581 agtatttact ctttaacaga agatgaaatt ggatatgtat ccctgcatat aggtgctgga
    44641 atagagagat tttttcaaaa taatattaag tgtaaaaacg tagtattagt atgtggttca
    44701 gggtatggtt caagtaggtt attagaggtt caattaaaca aagtttttca tgataaaata
    44761 aatatacttc aatgtctatc atttaatcaa tttttagcta gtgaattgtc agatgtagat
    44821 ataataatat cgacaattcc tttaaatcat gatagtattc ctattgtatt agtggattta
    44881 aaactattaa aaaaagatat agagaatata tctaagtcaa tcactaataa ttcccatatt
    44941 tatagtaatc ttttggacaa tttctttgat aaaaatttat ttattgttaa tcctaaaatc
    45001 aaagataaag atgagcttat aaagttgatg tgcaacaaat taactcaaag tgaaattgta
    45061 tttccatcat ttgctgaatc tgtattttac agagaaagtt tatcttctac caatatagat
    45121 gattttttag ctatacctca tcctatggaa ttaagctcta taagaactaa gatttgtatt
    45181 tccatattga atgaaccaat atattggagt gaagattcta ctgttaaatt aatcatgatg
    45241 ttagctataa ataaagatga ttatataaaa ataaactcca tttatgatat ccttttaaag
    45301 ataattcatg acaatgatat tagagatagt atatctaatt gtaatgattt tgataatttt
    45361 ctttccataa tcaagtctat agtatagatt tttatattac ataagtttta aaaactttaa
    45421 taaaatattt tttgttttta gcataaatag tataagtaag ttttgtataa tttgttatta
    45481 ttttgtattg attataatta ttatacaata aagattctgt ctcaaaatag agagagaaac
    45541 ttgtttttca ttgataaaat gataaaaata tatttgattt catacaaaaa agagtgtctc
    45601 atgaactaaa aagttcattt tgagacacca cctttattat tttatattat ttatctcttg
    45661 tatatattac tatagcatcc cttaaaaact tagctaatcc aggttgttct ctatcataat
    45721 atgatgtaaa acgttcatca tatacataca tctgtgctag agaggaatga gcttctttag
    45781 agtatgtgtt ccaagtgtaa ctcaaccatt tatgatgtaa ttttgcaact tcctgagcca
    45841 gttcactaga ggcatcacca gttttaaaag cttttttaag tttactaatt atttcgatat
    45901 ttaggttttg ccaattttca taatcttgct tagacatatt tttaagcttt ttatttgatg
    45961 tatctataat atctttacca tatttctctc taatttcagt tccataattt ttttcatttt
    46021 catcaatcat cttttcttta aaaccttcaa atttttctat atctgtcata gtgtattttc
    46081 cctccttcag agctatagtt ttagttacat tttctattag taaatcaatt tgctttcttt
    46141 tggctagtaa tttattatgg tgttctttta acgcacttaa actatcgaag tttggtgaat
    46201 ttataatgtt ttttatattt tctaagttaa ttcctaattc tctataaaaa agtatttgtt
    46261 gaagtttatt aacttcattt tgaccatata tacgataacc tgaagaattt attttaagtg
    46321 gcttaagaag acctatttca tcataatatc taagtgttct agtacttata ccagctagtt
    46381 tacttaattt ttgaactgta tattccataa gtaatacctc ctataaatta aatatacact
    46441 tttacgcaac gtaaatgtca atatattaaa atataaaaat ttatatcttt taataaaaat
    46501 ataaaaaaat atctttactg gatattttac acacaactgt caatactcac taatgaaaat
    46561 taaaaaataa aatttataga ctatctttac taaaatatag aaggtctata gcctaggagg
    46621 aactgtatga atttaaaaag aagcaatgaa aaacgagaag agtacagaag aatgtattca
    46681 gataaagaaa gttttttaag tttgattcaa aattttacaa gtgtctcaat agcaaaagaa
    46741 ttaactctta aaaatataga gttagaaaca tcttttatat gtgaatataa aggaaaagaa
    46801 gttgatataa tttataaggt attttctaaa agtggcaaag tatcacatta tatagtgtta
    46861 gaatttcaaa cagaaatgga tactgaaatt gtcccaagat tgaaatcgta tagagaacaa
    46921 atttggaaaa gttttattat gaaaaaaagc cttgaagaaa tagaagataa aaattttaaa
    46981 cttcctaaag ttataccagt ggttttatat agtggacctg aaaggttaag tagaaaaaaa
    47041 ggaattttgg atattgtaga atctatatcg gagttcagta ataattctag tatgaaaaat
    47101 taaaattaca taatgtgttt attggtctaa aatggaaaac tgtcgcataa acttgaatat
    47161 gaaaatattt atagatacag gttctatgtg gaggtgttcc atgagaaata acaagtctaa
    47221 ggtattgcta ggaatacttt gtctagcaac aggaatggct gtaattctgt caatgttgct
    47281 tcctggctgg atttggtcag cacttaccgc attaatactt attggatgtg gagcattatt
    47341 atttttttgt taaaatagtt ttaactataa agtgtggggt gagtattgat gaaagtagta
    47401 acaataaaat taccaaaatg gatttcaagt ataatcctaa aatttatgag aaagagtaaa
    47461 aatgattaaa ttaaaaagcc tacttacgga agtaggcttt taaacgtggt tactaagctc
    47521 tttcaatttt accagaacgt aaacatctag tacaaacttt tactctctta ggagctccat
    47581 ctataatcgc tcttacgctt cttaagttag ctgaccatgt tcttttatta tgtttatttg
    47641 agtgtgatac ttggtttcca gaaaccttac ctttatcaca tacgctacat acttttgcca
    47701 tctacgcaca cctccttaaa atgataacta tttaaagact aaaaacatat ttatattatc
    47761 ataaataaca aaaatttgca atagaaatat atatttgcct tacacatatt gaagaatttc
    47821 ttattatcat ataaaattat atatataatt ttatataaag taaatatatt tggaaaataa
    47881 ttattatttt tctttgaata tatatactat agaagaaatt ttatccaaaa acttttctag
    47941 gtttaaatta taccatattt atagtatgat atgattataa ttttatataa taaataagta
    48001 aaaatagtaa aaaataaatt aagaaatgtt tttaataaaa ataagcttaa gggggtcaac
    48061 catgagtgca aaggtaacga atcaatatgg aaatatagaa atagataatc aagtaatagc
    48121 tcaagtcgta tatagagctg caatggaaag ttatggctta gtaggtttag catataagtc
    48181 taaaggaata gtagagctat taaaaggcga gaacgcaact aaaggtgtaa gagttgagga
    48241 agtagaagaa gatgccatag caatcgaact ttatgttata atacaatatg gtacaaatat
    48301 atctactgtt gccaataata taatagatag agtaaagtat gtagttgaaa aaatgactgg
    48361 cgtaagagtt actagaattg atattaatgt acaaggaata agagttaagt aatttcatag
    48421 gaggaaacaa atgattcaat atatagatgg taaaaggtta agggagatgt ttatttcagg
    48481 tgcaaacaat ctccaaaaca ataaagagtt agttgacaag ttaaatgtat tccctgtacc
    48541 agatggagat acaggaacta atatgtcatt aacaatatct tatgccttaa aagaattagc
    48601 aaaagttgaa aatgataata tatcagatat cggaaaagca ttatctaaag gttctttaat
    48661 gggagctaga ggaaactcag gagttatact ttcacaaata atcagaggta tagctaaatc
    48721 tatagaagga aaaagtaaat tatcaacaga agatttagca aaagctttta aaaatggttc
    48781 agacacagca tataaagctg taataaaacc aattgaagga actatactta ctgtagttag
    48841 agaaagtgga gagtttgcaa taaaaactgc gaaaaaagag aaagatgtag taaagttttt
    48901 aagtatgctt gtgaaggaat caaattcttc attagaaaga actccagacc ttctaaagaa
    48961 tctaaaagaa gctggtgtag ttgactctgg tggaaagggt cttgtactta tatatgaagg
    49021 aatgttagct tctataaaag gcgataacat agaaataaaa aatgttgacc tagatactaa
    49081 tatttcaaca agtatggatt ttgcaaagag tactactagc acagatgata taaaatattg
    49141 ctattgtaca gaatttattt tagaaagttc taaggtagaa gatactaaaa taagagacat
    49201 aatgatggct tatggtgata gtctagcagt agttggagat gatggagtca taaaggtaca
    49261 tgtacacact aatgacccag gaaatgtact tcaagaagct ctaaagtacg gtcaattatt
    49321 aactataaaa atagaaaata tgaagttaca acatgaaaat acattactgg atgtagaaga
    49381 aaagaaagaa aatgatagtg aacctttaga agaagagaaa gagtttgggt ttatagctac
    49441 ttctatgggt gaaggtttgg caaatatatt taaagatttc ggagttgacc atataataga
    49501 aggtggtcaa actatgaatc caagtactga agattttatg aatgctataa agcatataaa
    49561 tgctaaaaat atatttattt tcccaaataa cagcaatata ataatggctg ctaatcaggc
    49621 aaaagaattg agtgataaaa atataatagt tatacctaca aaaaatacgc ctcaaggatt
    49681 tgctgcatta gtaactttta atggagaatt aagcgaagat gaaaataaag aagctatgat
    49741 gaatgcttta aactcagtta aatcaggtca agtaactttt gctgttaggg atacagtgat
    49801 gaatgaaatt gatgttaaag aaggtaatat aattggaatt gcagaaggaa atttattatc
    49861 agcaggagat tatgtggatg aagtaacatc aaaccttatt gaaaagttgg ttgatgaaga
    49921 tactgctata ataacattat tctttggtga agatgttaca gaatctcaag caaatgaact
    49981 acgtacttct ttagaagaaa agtttgaaga tgtagatgta gagttatatt atggaggaca
    50041 acctctttat tattacttaa tttcagttga ataatgatta taagaacctg tatgaccaag
    50101 tagcttttat aaaattggtt gtacaggatt tttgtgtagt aggtgatata tttgttggat
    50161 ttatataaag atgttcaata tgttaaggga ataggaccta aaaaagcaga taaattaaat
    50221 aaactgggta tatttacact aaaagaccta ttgtattatt ttccaagaca atttgaagat
    50281 agaaataatc taaagaaaat agcacaatta gaagatggtg agaaagttac gataaaagca
    50341 gtaatatcaa gtataaatac atttagccca aaagaaggta tgactttaac aaagattgat
    50401 gtaaaagatg agacaggctc ggctaaatta gtgtttttta ataaaagtta tataaaaaat
    50461 acttttcgtc caggagattc aatattagtt tttgggaagg ttaagaaaaa atttaataac
    50521 ttagaactta catcatgtga attagaatat cttactaatt cacctaagaa tacatgtaga
    50581 tttatgcctg tgtaccagct tacatacggt gttacaaata aagaaattat gagtataatt
    50641 agaacagtac ttgaagataa agaattaatt atacaagaat atatgccaca aagaattata
    50701 gaaaaatata ggctatgtag tatagatttt gcagttagaa acatacattc accaagtagt
    50761 aaggaatcat taaaaatagc tttatataga attgtatttg aagaattact tatactacaa
    50821 ctagggttgt ttgtatttaa aagtggcaga aataaagaag atggaataaa gtttgaaaca
    50881 agtaaagact taaaaaaaat aataagtgct ttaccattta aactgactaa agctcaaaac
    50941 agggcattag atgaaattat acaagatatg aatttagaga aaataatgaa tagattggta
    51001 caaggtgatg tagggagtgg taaaacagta gtagctctct tagcacttgc aaattgtgtt
    51061 ttaaatggtt atcagggcgc tttgatggca cctacagaga tattagcagg gcaacattac
    51121 atttcactta ctgagtctct aaaagatttt ggaataaatg taggtctatt aataggtagt
    51181 cttacaaaaa aacaaaagga tacagtattg gaacaaataa ggaataatga gattgatata
    51241 ttaataggta cacatgcact aattgaagat aaggttgaat ttaataatat tggtttagtt
    51301 ataacagatg aacagcatag atttggtgtt atgcaaagga gcaaactttc attgaaagga
    51361 gcaaatcctg atatattagt aatgacagca acaccaatac caagaacttt agcacttata
    51421 ctctatggag atttagatat ttctattata gatgaacttc ctccaggaag acagccaata
    51481 gaaacaattg ctattgaaaa aagtaagcga gatagagcat ataataacct tgtaagaaga
    51541 gaggttgaat caggaagaca agtgtacatt gtatgtcctt tggtagaaga aagtgaagct
    51601 atagaagcta aatcagcagt tgaacttgta gaggaattaa gagctgaata tttccacgat
    51661 ttaaggcttg gattgcttca tggtaaaatg aaatcgagtg aaaaagacga agtaatggaa
    51721 cgttttaaaa ataaagaaat agatatttta gtttcaacaa cagttataga agttggtgtc
    51781 aatgtcccaa atgcaacatt aatgataata gaaaatgcag aaagatttgg acttgcacaa
    51841 ttacatcagc ttagagggcg agttggaaga ggtagtcata aatcgtattg tgtactaatt
    51901 tatgattcta aaacagatgt atgtagacaa agaatggcta taatggaaga gaccaatgat
    51961 ggttttaaga tttcagagaa ggatttagaa ataagaggac ctggagaatt ttttgggaca
    52021 aggcaacatg gtcttccaga acttaaagta gcaaacttat ttaaacatat aaaaatattg
    52081 aagttagcac aacaagaagc tcgatatata ttgggtgaag ataataatct acaattgaaa
    52141 gaaaacatgg cactcaaaaa agaaattata gataaattta aagatacatt gaaagaaatt
    52201 tcattaaatt aattttaaat tatgttaaaa tattactaat gtaataatgt gctgaaggga
    52261 gattgtcata ttgagagtaa tttcaggaaa agcgagagga ttaaaactaa atactccaaa
    52321 aaatgaagat gtaaggccaa ctacagatag agtaaaagag tctctattta atatgataaa
    52381 ttcatatata atggaaagtg aagttctgga tttatttgct gggactggtt ctttaggaat
    52441 agagtgctta tctaggggtg ccaagtcatg tacttttgta gatatcagta aggaaagcat
    52501 agatattgtt aagtccaatg taaaaaaggc aagagttgaa agtgaaagta ttattttaaa
    52561 ccttgatttt aagactgcaa tagataaact taaattacaa aatagtaaat ttgacataat
    52621 ttttatggac cctccgtatt ataaaaatat gtttatagaa gctattgaaa aaattgataa
    52681 ttctaatcta ttgaacgaag atggaataat agttgtagaa catgatacga atgatttatt
    52741 tccagataag atatgtaaat tggagaaaac tagagataag aaatatggaa atactacatt
    52801 aactttttat aagatggagg cataatatgg aaaataaacc tagaaaagct atatttgcag
    52861 gaagttttga cccaattact aatggacatt tagatattat ttgcagggct tcgaagttat
    52921 ttgacgaatt acaaatagga gtattaaata atcctaataa aaagggtcta tttagctttg
    52981 atgaaagagt aaaacttata gaaaaaagta caagccattt aaataatata aaagttgtga
    53041 cttttgatgg tttattaata aattactgtc aggaaaatgg gattggagca ttagttagag
    53101 gtgtgagaag tggtgctgat gttgattatg aacttcagat ggcacatatg aatagagagc
    53161 ttaatccaga tatagagact ataattttac caagttgtac aaaatattca tttataagtt
    53221 catctttaat aaaagaggtt ttgctctttg atgctgatat aaaaaatttg gttccaaaga
    53281 ttgttttgga agaattaaag aaaaaaacta gtgggggtaa ttgatatatg aagatagatt
    53341 tagaaatgat tgaactattt gagcagttag aggagatatt tagaagtgct tctacaatcc
    53401 ctttctcaca taaatgcaca gtggataaag atgaggtttt agcaataatt aatgatataa
    53461 gaactttaat accagaagaa gtaacacagg cagtatggat taataaagaa agaaataaaa
    53521 taataagtca agctaagcaa gatgctacaa atatagttga acaagcgaaa aaagaagctg
    53581 agagaataca acaagaatat caagataata tagaggaatt aaagaaaaat tctgaagatg
    53641 tagtaaaggc atatgtagaa tccagcgaac ctgttgttca agcagaccaa agagcaaaag
    53701 atatagttga tagagctgag agaatagcca atgagataag aattgggtca attgaatatg
    53761 cagaggatgt gctttctagt gttgagtata atttaagaga aatattagaa gaagtaaaaa
    53821 gagataaagc tgaacttaga cctaaaaaat aaattttaaa taaataaaaa tggagctatc
    53881 acacaaaaaa ttccaattga tgtgtgatag ctctctttta atatagcaat tttttgttat
    53941 ataattgtgc tttttagatt acttatatct tattttgata ttataatgta gcttaatctt
    54001 ttatttgttg aaatcaactt atttatttgt ataaataata taggttattt tcaaattttt
    54061 ttaataattt taccactgtc ttcttttaga ttagggttag actgtgcaaa attataaaat
    54121 aatactaaat catgtgcaat tatttggtat ggcactacat gtagaaaata tagataataa
    54181 aattaaggag gtagtatgaa ggaaagggct aaaaaaatat tagattttat tattaaaaat
    54241 aacaatgtaa catcacaaga actacaagaa aggtttaatg tttcaaagag aactatttat
    54301 tacgatattc tagctataaa tgaacaacta ggaaaaagtg gtaatataaa aaatgtaaaa
    54361 cacaaattta tatttgaagg taatttatgt gatgcaagga aaataatttc aactgaagaa
    54421 gataaatttt tagatagtga ttacagaaaa acttttatat taaacaagat attacttggc
    54481 gaaaaaatat caatagaaaa actaacaaat gaaatgttac tttcaaaaaa cacagtagta
    54541 caaacaataa ctgatgtaaa aaaatacctt caaacaatgg ggttaagatt agagtataag
    54601 ggaaagtaca aaattatagg tgatgaatac gttattagag agctgtttct gataattgtt
    54661 caagaaaatg tactggaaat taattctata agtaaggaag taagtagttt cgatacaaaa
    54721 ggacatataa aacttactga ttattcttta ttaaatctaa ctaagtttgt ggaatttcta
    54781 aataaaagga taagagatgg gaaaacatta tactcatata aatatctaaa tgaagctaaa
    54841 aaaattagtt actttagtaa ttgtaaagaa cttttatgtg aagaagccaa tgaaaatgaa
    54901 caagcctata tatgcactta cataagttca cttcctagct taaatagtga agttaaggaa
    54961 gatgttgttg aagaatatgt agataaactt atagataagt ttgaagtaaa tacagcaata
    55021 aaattagaaa gtaagcatga gtttaagaaa aatattttaa ggcacctcca ctcttcttac
    55081 aacagaatac gatttaagtt tcctattaga aatccaatgt tagatgagac taagtataaa
    55141 catgagtcac tttataaaat tataaaatca attatagaaa atgaagaaga gtttcctgta
    55201 tttgagggga taagagaaga agagatagga tttatagcag cgtattttgg agggtattta
    55261 agagggtcta gggataatgg cctaagaaga aataaagtct tactagtttg tcctaatggt
    55321 cttatggtat caaagagttt ggaaatacaa ctatataaat acataccaac catagaaata
    55381 gtaggtatag tgtccattaa gcaactaaaa gaagtaaatg tatactacga ttacataatt
    55441 acaactatag atatacaaaa tgtaaacaat gtaattgttg taaatcctct tttaacatca
    55501 tcagatgttc aattacttat gaacaaacta ataagtgtaa aagaaaacga gaagtatttc
    55561 aatcttgaat taataataca agctataaga aaaaatggag ttatcaataa tgaagaagca
    55621 ctaaaagctg atttattaaa cataatacac aagatagatg aaggagagat gtatcaacca
    55681 atgttaaagg aattaattaa tgcagaaagg gtcaatataa taaaaagtgt tagagattgg
    55741 aaagaagcaa taaaaatagc ctcaaagcca ttgttagaag ataactctat agaagagtta
    55801 tatatagaaa atatgataaa gtcagttgaa aaatatggac catatattgt tttagctgat
    55861 agatttgctc taccacatgc aagttctaaa gaaggagtaa acaagcttgc tatgtcttta
    55921 ctaatagtag aagatgaagt tgatttatta ggaaaaccag taaatatatt tatggtatta
    55981 gctgctgtag ataacactac tcacattaga gcattagcat cactatcaga gatgatgtac
    56041 gaggaagaaa atgtaaaact aataattaat ggtgataaaa gttcaatact agaacttata
    56101 aataagcaaa attaggagga atgaaaaatg aagatattag cagtatgtgg ttttggtgta
    56161 ggttcatcaa tggtattaaa aatgacaata caaaaggctc taaagcagtt aggtatagaa
    56221 tgtgaagtag aaaatacaga tataaattca gctagaggtg ctgattgtga ctgtatattc
    56281 acaagtcaag aattgttaaa tgaattaaaa ggaacttgta atgtagatgt atatccagtt
    56341 aaaaagtaca tggatttagc agaagtcaca gaagttgttc aaactttttt aagtgataaa
    56401 aatgataaga aatagtataa gttttaaaaa gtaaatttaa gttaatcaga ataaaataaa
    56461 aacttactaa attcaaaaat agtaagaaag agaggaggga tttagtggta gaaaacttaa
    56521 acagttgacc tatcactaaa aaatataatg cttgatttta tttcaaataa tattttacgt
    56581 aatccatcta tgttaattgg attaatagca gcatttggtc ttgtactaca gaaaaagaaa
    56641 gcatctgatg ttataaaggg gtcactactt gcagctttcg gaattataat tatggagact
    56701 ggaacaggta tgttagttag ttcaatagca ccaattaatg gagctttcca aagtataagt
    56761 ggtggtgcag taacaaaagg tttaagtgat gttactttta ctgcaagtta tggtggaatt
    56821 ataggtttag caatgtttgc gggtttagct attcacctaa tgatagcaag atttactcct
    56881 attaagacaa tcttcttaac aggtcacatg ctttattggt tcccattcat atttgtagct
    56941 tcaggagttg aagctggatt aaatggtgga gtattaatag cttttgcagc agtattatca
    57001 gcactctatt ggtcaataat gccttggtta ttaagaaaat atgtgtttga tgttatagga
    57061 gatgattctt ttacattagg tcatccatct ggttgtttag cacttatatc aggatttgtt
    57121 gctaaattag taggaaataa agaaaaatct acagaagata taaacatacc tcaaagttta
    57181 tcatttttta gagaaatatc tataagtggt ggaatggcag tgtttttaat gtttatagtt
    57241 gttgggatag taataccagg tgcgtttaaa gatagtaatg agtttattgg aacgtatgca
    57301 ataaagcaag gtctttcttt tggagcaggt cttataataa tgcttcatgg ggtaagaatg
    57361 ctaataaatc aaataatgcc agcatttcaa ggtatatctg aaaaagttgt gccaaatgca
    57421 ctacctgctt ttgactgtcc aatattattt aattataaac caaatgctgt attaatagga
    57481 ttcttagttg ctatgctaac atctacagct atgattttaa tatgtaacta ctttaatgta
    57541 tttaatttgc tacttatacc acttgttata acttcattct ttgagtgtgg agcagcagca
    57601 gtaataggag aatcacaagg tggtatacgt ggagctataa taggtacagc tatagctgca
    57661 atatttatgg tagttttagt aggaatatct gctgtaattt actcaggaac tattcaaaat
    57721 tggatactaa tatttggagg taacgacctt tcattatttg gtataattag taagtttata
    57781 ggttcactat ttggaggaat attatagata tgaaatttaa atacatagat gagataagaa
    57841 gattaattga tataatagaa aacgaagaaa aagtcaatat ggaaaaagca gtacaaatcc
    57901 ttgttgaagc aatagaaagt aaaaatgcta tattttcatt tggagcttca catgcaggaa
    57961 tattaacaga agaattattc tatagagcag gtggctgtgt tcttataaat ccagtatttg
    58021 caaaatctct aatgttagat acagcgccta taactcacac aagtaagatg gaaagattag
    58081 aaggatatgg tacagctcta gctgataaaa ctccaattaa aaaaggagat gtagttatag
    58141 ttcattcagt atctggtaga aatccagtaa gtatagagtt tgctatgaaa gctaaggaaa
    58201 ataaggcaat agtaatatgt ataactaatt taagttactc aaaaagtgta tcttcaagac
    58261 attcttcagg aaaaaaactt tatgaagtat gcgatttagt gatagataat catggtcaaa
    58321 agggagatgc ctgtgtagag atagatggat taaaccaaaa agttagtcca acttctactg
    58381 taatagcaac tactgtgatg aactctatta tagctcaagc tactcaggaa ttagttaata
    58441 aagggctaaa gaatcctccg attttctata gtgccaatat tgatggtgga gatgagttaa
    58501 ataagaagat ttttgatgaa tataaaagtg taattcatta tgaatattaa ggttaaaaaa
    58561 atatgttaat gaactttgaa gtttatcaac aaagaatatt aataatatat aataaatgct
    58621 atcatttaaa agctgtaggt aaaaatctac agctttttat tattgtagat taaaaagatg
    58681 cgtaattaaa ttttaaattg gagaaaataa attggaaggt atcaattata aatattagaa
    58741 acgttgtcat agaaaaaaac tatattaaaa aaaagtacat agaaaaaact gattagacaa
    58801 taaatacatg ctttgataat attttaaatg gagtgaaaat gtgtagaatt ataatgaaaa
    58861 aagaaaataa aaatgaaaaa agaaaataaa atggagggaa taaaagtggg tatgttaaaa
    58921 aaattatgtt cactagctat ggtagcaatt atgactacaa cacttataac agggtgttca
    58981 agtggaaatg gaaaagattc aaaaaaggat ggcgaaaaag aaaaactagt tctttggatg
    59041 ccaccagtag aaaataatat gaaggaagtt tgggacccta ttttagataa atttgaggaa
    59101 aaaaataact gtgaagtaga tttacagata attccttggg ataattattc tgaaaaattt
    59161 gcaacagcta taagtgctgg cgaaggtcca gatgtaggat atatgtatgc agaaatgtat
    59221 ccacagttta tagaaagtgg agcagtagaa gatttgacta actatgcaac taaagaggat
    59281 aaagagcaat ctatttatat aaaaacatct gaaatgatgg gtggaatgta tggtatgcca
    59341 ttccaagcag caaatccagg ggtattatac tataacaagg atattttaga gaaattagga
    59401 gagaaacctc ctaagacatg ggaagatttt aaaagaattt gtaaaaaagc aacacaagat
    59461 actgatggtg atggaaagat agaccaatgg ggattagctc agggatgggg agctaaaact
    59521 tttggtaact taaactggaa ctggtatcct tatttatggc aagctggtgg agatattttt
    59581 aatgatgatt taaaatcggt taaatttaat gataagagtg gtttagaagc agctaatttc
    59641 ttaaaagaat tacaagcata tgtgcctgaa gattctttat ctaaagatag taatgaaatg
    59701 atagaaagcg tatttggacc agggaaagca gcatttacaa taatgttatc ttctgctgca
    59761 acaagtgtat ttgatgaatc attcccggat ttaaattggg ggtttgtaac tggactagaa
    59821 gataagaaag cagcaacttt tggagcagta gaccatttat ctttaatgtc atctgctaaa
    59881 aataaagaac ttgcatacaa gttaatacaa catatgttaa gtgttgaatc aatgacagaa
    59941 tttcataaag caataccaag agcaccaata acaaaaggtg aaccatatca aggtgatgaa
    60001 agattcaaag aaatggtgga aaatgacaaa aatgtatata gaccattagt agtaggacct
    60061 catggagttg aaatatatga atatttatgg aaagaacttc aaactatgat ttcaggagat
    60121 aaaactccaa aacaagcatt agatgatgct gcaaaatatt caaatgattt attagcacaa
    60181 taaaagttta aagctgtaat atgttgtaaa ggactttaca gattaaaatt agcattgtat
    60241 ttataaatac aatgctaata tttatattgg agaggataaa atggaaaact tagttagaga
    60301 gtttgaagaa aattcaaaaa gaaaaaaaac aaaattaaat attaaaccat atatgtatat
    60361 attgccattg ggaataattt tagtggcgtt ttatgtgata ccaataataa tgtcaatata
    60421 ctttagtttt acaaagtata atattattag tccagccact tttataggtt tagaaaatta
    60481 taaaaaatta tttacagatg aaacattaaa agtatctatt ataaatacta ttaaatttac
    60541 tgttgttgta gtaccttgcc aaactatatt atcattgatt ttggcagttt ggattacagg
    60601 aaaaggaaat agtaaaatag cttcatttgc taaaggtgct atatttatac cagtattatc
    60661 atctatggtt ttgataggta tggtatggag ggctttattg aatggagaag gttctattat
    60721 atatcaggta ttaggtgcct ttggaataga atcatctaaa cttttaggag atagtaagac
    60781 agcattacct acacttatgt ttatatctat gtggaaaaat atagggtatt tcatggtaat
    60841 ttatatttca gctataatga atttaccaaa acactgctat gaagtagcga aggttgatgg
    60901 ggctacaaaa cttcaagaat ttataaaaat aactgtacct ttattgaaac caactacaat
    60961 aatggttgta tttttagggt cgatatggtc attacaagta tttgacttaa tttatactgt
    61021 gacaggtgga ggtccaggta tatctactat gagtatagtt atgcatgcat ttaacttaaa
    61081 ctttaaaaac tttaattctg gatatgcaat gactgtagca aacgtattat ttttgttaat
    61141 agcagtagtt tcgattttac aaaataagct tgtaaaacga gacaattcag atttttagaa
    61201 aggtaggtat aatatgaaaa cagcaagaag attattaagt gatggtttac ttttatttat
    61261 agcgtgtgca agtttggtac cttttatata catgttgata atatcattga agataacata
    61321 taactcatat agtttggata tatctttttc aacagtaact cttcaaaact atatagatat
    61381 ctttactaaa aaaggatttg cacaatattt ttttaataca gcaatagtat ctttttcagg
    61441 tgtattatta aatttagtat ttagtacatt agcaggatat tcttttgcga agatggattt
    61501 taaaggtagt gataagttat ttttatttat gataatgact ttaattatac cttcccaagt
    61561 tacaatgata ccactatata taataatgaa acacttagga tggataaata gttatcttgc
    61621 acttattatg ccaataccaa ctgcatttgg cgtatttata atgagacaag ctattttagg
    61681 agtaccaaaa gagttattag aatcagcaaa gatagatggt tgctcggatt ttagaatttt
    61741 aatacaaata gtattgcctt taatcaaacc agcattaatt acactagcaa tatttacttt
    61801 tatgggagca tggaacgagt ttatgtggcc tcttatagct acaactaaag atgcaatgag
    61861 aacattaaca gttggattat ctactcttaa gacattccag ataactaatt atggacagat
    61921 gatggcaggg gctacaataa catttttacc tccatttatt ttctatttga ttttacaaag
    61981 taaatttgtt gaaggtgtgt ctttgtctgg tataaaaggt taaatagtct aatttaataa
    62041 cataaaagaa acttatataa atatggagga atttaaacta tggaaatttc atatgtactg
    62101 aaagattgca cattcaaaca caataaatac tcagttatag aagctgaaac ttggaaagag
    62161 aaggatttgg atattgtagt agctaaaggt gaaaaatttg catttcaaat tatgctaaaa
    62221 gcaacagaag aatttaattg tacaattgat aaaagcagta ctatatcatg gaaaggactg
    62281 gaaaatagag taagattagc attaaatgtg cctaatagtt tagaaaataa ttttagtata
    62341 aatatattag gatatgttca agatgataca aaggcatttg tgaatgatgc tattttaagg
    62401 gataaagatg tgttagtaga gcaatatttg cctcaaacat tttggattga aggtcaagta
    62461 ccagaagatt ttgaagaaaa taaccttaat ataggtattg atatatttaa aagctttgga
    62521 tatgaagatg aagaaaaagt ttgtacaatt gatgttcctg taaaagtaag aaatgtcgtg
    62581 ctaaagcctt tagataaaag caagttcttt ttagatttat ggcaacatcc aagttgttta
    62641 gctagaatgt ataaagttga gttatggtct gatatacatt ttgaaatagt cgataactat
    62701 ttaaaagaat tagcatcttt aggagaaaaa gttgcaacag ttatagtttc agattatcca
    62761 tgggcagggc aaagttgtta taaagtttat aaaaatccat caaacctata tgaatataac
    62821 atggtaagtg tatcaaaagg attggatgga aagattaaat gtaactttga gagtatggat
    62881 aggtatataa gcatagctga taagtataaa atgtctaagg agatagattt atttggtcta
    62941 ttaggtaatt ggtgtgctgg tgagtttgga aatcctgtag aaggttataa ggaccctata
    63001 agagtaagat attttgatga aaatgataaa gtatttaaat ttataaacaa tacaaatgat
    63061 ttaaaagaat atataggatt agtattaaat catttaatag agtgtggatt atgggataga
    63121 gtaaggatta tagctgatga accaaataat ccagaagtag tcaaagagtg tatagaattt
    63181 ataaattcta ctgtaggtac tcatcaagtt aaatataaat cagcaactca cgaccaaaac
    63241 tttttagata gagctaaaga tgaaattgat gatatgtcaa taaatttaaa acttactata
    63301 caaaattata aagatataga aaatcttaag aaaaaaatca atgacaaggg tgggatattg
    63361 acttggtttg tatgctgttt tccagagaaa ccaaatagtt ttttaagttc tccttttgta
    63421 gaaaatagaa taataggatg gtatacttat tactttggtc ttgatggatt tttaagatgg
    63481 gactataatt tatggacaga agacccttgg aaagattcaa gttacaaatt ccctatttgg
    63541 aaagctggag atatgttctt tgtttatcct ggaaaagatt taaagccagt tagaagtgtc
    63601 agaatggaga atttaagatt tggaatacag gactttgagt tatttacaat gttagaaaaa
    63661 gaaaagggca gagagtatat agaagttgag cttatgcaag aattattaaa taaaaaagaa
    63721 aatgctgaaa ttaaaggttt tggtgacata gaattaggat attcacttga taattgggga
    63781 tatgataaag ttaaaaaata tgtattagag ttgttagaca gagtataaaa aaatataaga
    63841 gtgtctcaaa atgaactttt tagttcatga ggcactcttt ttgtatgaaa tcaatatagt
    63901 ttcattgttt caacaatgaa aaataggatt acttatattc taagatagcc ctttagtttt
    63961 ttagttgtat tcaatgtttt aaaactaact ataaacgcta taaagtttat aaatgacaat
    64021 aattatatgt aacatgatgt actttaattt gctataatag ggattgaata atattatatg
    64081 gaagataaca ttgtttgggg ggattaatat aaaaagaata ggtattatta taatgttttt
    64141 tttaagtata gcttttattg gattttatct tgcaataaga ggtaacagtg atacagttaa
    64201 gatgcaacga gggataaata taggtaatgc actagaatca cctaaggatt ttccgtggga
    64261 tgtaaaaatg tcaaataagt tttttgatga tataaaagat gcaggttttg acacagtacg
    64321 tataccagta aggttttctg attatacgtc agattctgat aattttaaaa ttgatgaaga
    64381 attttttaaa aagattgata aatatgtaga ttatgcattg gataaagact taatagttgt
    64441 gttggattta catcattttg aagaaattat gaaagaacca agagttcata aagaagagtt
    64501 tttaaaaata tggcaacaga tagctaatag gtatcaaaaa tatgataaaa aattggtatt
    64561 tgaattatta aatgaaccta aagaaaattt atcttcacaa ttactaaacg aatacattga
    64621 agaagcaata aagataatta gaaaaactaa ccctaaaaga actattatag tgggaccata
    64681 taatttctat caaattgatt atttgaatga attaaatgtt ccaaaagatt ctaatatagt
    64741 agtttctttt cactattacg aaccaaatga ttttgcattt caaggaaaca tttatcataa
    64801 tggatttgag cacttgagca atattacttg ggaaggaaca aatgaacaaa tggattattt
    64861 aaaaaaaagg tttgatattg tagaaaattg ggcaaataaa aataaggtaa aaatattctt
    64921 gggtgaattt ggagtaacaa aagaagcacc agaagcttca agaagagctt ggataaaagc
    64981 tgtaagagaa gaagctgaaa aacgaaactt ttcatgggct tattgggagc ttgcttctgg
    65041 atttggtata tacaatcaaa ttgaagggac ttgggataga gacatattaa gtgcattaat
    65101 agaaaagagg tgattttatg aagaaaaatt caaaaaagat acttataact ttaactatta
    65161 ttactaatat cgtatatata ttgtggagaa ttttttacac agtacctaaa gaagaaggga
    65221 tgtttgcctt aatctgtgct ataatacttc tttttgtaga gataatgggt atgatggaaa
    65281 tgtttgtaca ttattatggt atgtcaaata ttgagtatcc tgaaaaacca gtcataagtg
    65341 aagaacttta tccacatgta gatgtattca ttgcaacata taatgagtct gttgatttgg
    65401 tgagaaaaac tgtaaatgga tgtattcata tgcagtatcc agataagaaa aaggtacata
    65461 tatacatatg tgatgatgga aatcgtgaag aaatgcgtat tctagcagaa aaaatgggtg
    65521 taaattacat aactagaact gaaagagaag gagcaaaagc tgggaattta aataatgcaa
    65581 tgcaacatac aaactctcct ttgattgcta cgtttgatgc agatatgata ccaatgcatg
    65641 actttttaat tgctacagta ccatactttt tgaaaaatga gcaagctaaa aaagatggag
    65701 aaaaagagga gtatgaaaag gttggttttg tgcaaactcc acagagtttt tataatccag
    65761 acttgttcca atttaatctg cactctgagg gaaggattcc aaatgagcaa gattattttt
    65821 acagagatat tcaattggct agaaatagga caaattctgt aatttatggt ggtagtaata
    65881 cagttatttc aagggaagca cttgaagaag ttgatggatt ttatacttat tctattacag
    65941 aagattttgc aacaggtatc ttaattcaaa gtaaggggta tagatgttat gctattccag
    66001 aagtacatgc atcaggttta tctcctacag atttaaaaag tcttattaag caacgtgaaa
    66061 gatgggcacg tggatgtata caaactggta gacgtctaaa tattttgttt aggagaggtt
    66121 taggtttttg gcagaaaata agttatattt cttcaattac ttattggtat gcaagtataa
    66181 aacgctttgt atatataatg gcacctattt tattttctgt gtttaatgtg attgtagtaa
    66241 aatgtacatt acttcaagta ttggtatttt ggttgccaat gtatatttta agtagtttat
    66301 ctcttaaaat attttctcaa aatataagaa atactagatg gaccaatata tatgaaacta
    66361 taatgtttca gtctttaatg ccagcagtaa tacttgaaac gtttgcaata tctaaaaata
    66421 aattttcagt aacaaataag aataaattag aagaaaatag aatgtataag tttttacagg
    66481 gaatacctta ttttatttac atggtcttat ctatcatagg aattttaaaa atgtttgtag
    66541 caatatttaa aatgagttca atgacatatt cagttgtatt attttggttg attggaaacc
    66601 tttttaacct tgttatggct acattattta tatcagggag acaacagtta agaaagtctg
    66661 agcgttatat tgctgaaatt gattttaagt taaagcaaaa ctcttatgtt ctttcttcaa
    66721 aaacgattga tatatcagaa aatgggtttg catttttgct agaaaatcca gaatatattt
    66781 ccccagaaga agagttcgag gtagagttta gagaaaaatc aggaaatgaa atgtatatag
    66841 ctaatatgaa agcaaagatt gttaatgttg tggaagtaaa ttcaaagtgg aaatatgcag
    66901 cttatattac acatattgaa gatagtgaaa tagataattg gatgtgtatt gttcacgata
    66961 gaatacctac tttaccgatg acaatatcta atcaactagg tttctttgat gatttgcaaa
    67021 ttaatgtaaa aaaacgtatt gaaaagatta gaacattatc acgaagaagt ccaagaatca
    67081 atatgaattt tcagatggat ataaaaaata caggtaaatt aagaatagta aattttaatt
    67141 atcaatatgt attattaaat tttgagaata aaaatattta tcctaaagaa atagcattgg
    67201 aaattaatga aaatattgtg ttagaatgtg atttatgtga gggtaaaatc gatgaaagag
    67261 gtctcttata taaagtaaat aacattgaca gcataatgca aaatttcttt ttaagagatg
    67321 aaatgatgga ttggatatta caaaataaga caattcctgt ttcaaatcct agtgaaaaga
    67381 aggaaaaaag tatagatgag tttgaaccca tggaatatat ttaggagaga tgaaatgaag
    67441 actttaaaag tgtttttttg ttctgcaaaa tatcttattt tggtgtttat tttttttata
    67501 aatactactt ttataagttc agcgacaagt gataaaattt tagatttatc ctttaaaaag
    67561 atagagactg atttaagttc taggattaca tatgaagata caggtgtaaa aatagaaaca
    67621 gatagttcta aaagtgataa ggaacgttat ttatatattt accaaaatat aaaagaaaat
    67681 tggagtatgt ataataattt ttatattgaa attcaaaata aaaataaaag ttcccagaaa
    67741 ataaatttaa gtatacaaag taagaatatg cttgaattta ggttaaaaga aggtagtgaa
    67801 atatttttgg aagataaaaa tataatatat tcagataaaa taaaagaagg atgcatagaa
    67861 gtaccaggtg aatttgaagg caaaatttat gtgaacttta atagccttat aaatgagaaa
    67921 agtaatgttg tgctggactc aagtatgctt tcaaacattg ttagttgggg aattacattt
    67981 attccatctg atgaagaaca taatattgtt attataaaaa agatatcttt attgtctgaa
    68041 gagaaattaa gttttttaca taatattaaa ataactggca atgaagaagt acaaatacca
    68101 gtattgggtc aaagtataag tcagtatgag gtattaggtc ttaaacgtga ttctaaaatt
    68161 aagtattctc ttatgggaaa acaagataat gtgagcatat ctcaaaatgg taaattaaca
    68221 ttaagtaata aagccgaacc tggacaaatt attttacaag ttaatgttga tgataagttt
    68281 aaaattggaa ggaaaatagc attaactgaa tcttggagta ttaataaaaa agataaggat
    68341 ggtgttccat atacattggt atctcctgag caatcaccaa cagtacaata tatgaaaaaa
    68401 ataaacttta tgaataacat cataacgttt gttcgaattt tatttgtatc tctagtaata
    68461 atatgctttg gaatatattt atattggaaa aaatgttcaa aaactaagta aagagaggag
    68521 gttagattgt gttattttca agtttaattt ttttatttta ttttttacct ataactttgg
    68581 ttttatatta tgtatttagg tttaaccgaa cgatacagaa catgatattg cttgctgtta
    68641 gtttattttt ttatgcttgg ggagagccaa aatttgttgt tatcatgata gtttccataa
    68701 taatgaacta tatatttggt ttactagtag atagatatag ggaaagtaaa ataaaagtaa
    68761 aagttttttt agttttgatg tgtgtatata atataggtgt tttatttata tttaaatatc
    68821 tagcttttgc gctaagaaat attagtgaac ttattaatac tgaactaact atacctagta
    68881 ttgttttacc tataggaatt tcatttttta catttcaggg aatgtcttat gttatagatg
    68941 tatatcgtag acatggagaa gtccaaaaga atccttttta tgtgggactg tatatagcat
    69001 ttttcccaca attaatagca ggtcctatag ttagatatga gagtgtggca gaacaaattc
    69061 tcaatagaaa agaaacttgg aataaatttt ctattgggac ttgcaggttt ataacaggtc
    69121 taggcaaaaa agtattaatt tcaaataaca tggctatagt agcagactat atttacacta
    69181 tgaatagtca aggagaaata gctgcatcac ttgcatggct tggttcaata gcctatacta
    69241 tgcaaatatt ctttgatttt tctgcttatt cagatatggc tataggttta ggtcttatgt
    69301 ttggttttaa atttgaagag aactttaatt atccatatat atcaaaatca attagtgagt
    69361 tttggagaag atggcacatt tctttgggaa tgtggtttaa gagctatata tactttccgc
    69421 ttggaggttc tagagtagca aataaagata ttatgattag aaatatgttt atagtgtggt
    69481 tatttactgg aatatggcat ggagcagaat ggacatttgt aatttggggg attttaaact
    69541 ttgttttctt gattatagag cgatttataa tgtttgaaaa gattgaaaat cacaatttta
    69601 taaaacatat ttatgcgtta ttagtagtta actttgggtg ggtattgttt aggtcaccta
    69661 atttaaaaga agcatataat tatttcaaag ctatgcttgg aggcaatgga gttatatgga
    69721 gtgattatac atatatgttt ttaaaagaat actgggtttt ctttatattt gcatttattt
    69781 ttagtgtacc tattgcaaag aaaatcaata agtttgttgt tgaacaagct aaatatagta
    69841 tgatatttaa cgtattttat ccaatctcag ctattttatt gttctttatt tctgtgacat
    69901 atttagtaac tggaagctat aatccattta tttattttaa tttttagttg ggaggaaaag
    69961 tatgaataga ttttttaaag taagattaat aactgcaatt atgttcttaa ttattttatt
    70021 cgctttctct atctttaata tttgttattc tggaaaagat atgatacagg agataaaaaa
    70081 ttcagttgct gaaaaaagta gtttaaaaga tacaatatca tctattgata acacagtaaa
    70141 tgacaaagta atatataaaa atacgttcat tgaaacttat ggctacttac aaaagttaat
    70201 gggtaaaaat gagttttcaa aatttagtgt tgtaaaagat acttctggaa agatgcatta
    70261 tacatatttt gctaaagctc caaatccagt tggtgtgata gcagataggg taagaaaatt
    70321 ttctgaggaa atggaaaagc aaaacactaa attagtttac ttaatgactc cagataagta
    70381 tataaaagga gtgacaaaat ttccaaaagg aataccttat tcttatagca atgagacagc
    70441 agataatttt ttaaatcaac taaaaaagta taatgtggac tatattgatt ttagagaaaa
    70501 tattttaaag agtggtattc caaaagatga tttatttttt aaaacagacc atcactggaa
    70561 agtagaaact tctttttggg catttggaga attagttgag caacttaata aaaaatacaa
    70621 tatgaattta gatgaaaatc attactatag agataaagaa aattataact caattgtata
    70681 tcctaagtca tttcttggtt ctatgggaag aaagactggt atcttatatg gtggtataga
    70741 tgattttaca ttaatttatc ctaaatttaa gactaattat acttattata cagattctaa
    70801 atctcaaaaa tttgaattaa aaggaaggtt tgaagagagt ttaatattat catatccttt
    70861 taatgcagac cttgatttaa tggatggtca atcagataag tattttacat atttattggg
    70921 gaatagacca ttagttaaaa taaaaaatat agaaaatcca gatggattaa aagtgctgtt
    70981 tgttaaagat tctctaattg taccaacagc agcatttttt tcctctgttt gttcatctat
    71041 agatatgata gaccctagat attatgatgg agatatacta gaatatgcaa aatcccatga
    71101 ctatgacttt gtttttatat ctgtatatcc ccaaaatctt acaaaagaat tttttccgtt
    71161 ttgtaagtaa atttctaaag aaattttctt ataaaataaa aaataaatgg ctaactagtt
    71221 aaaagttagc catttatctt aagtgttact ctaagaaatg ttttttttac caaatacttc
    71281 tttatctatt tttccaagtg attttcctac agtaattgat gataccatag caccattaac
    71341 atttatcatg gtacgtccca tatctagtat agggtctatt gcaagtatac caccaactaa
    71401 tggaaaataa gaaccaagac caactccaga gataacaact gaaacggcca ttgtagcagt
    71461 tcctggaaga ccagctattc caaacgaact aattgttata acaattaaca acataacata
    71521 aaggctcata tccatgttta ctccagccat attggcaagt gttacagcca ttaaagcagg
    71581 atatatacct gcacaaccat tcatacccat atttgcacct aaacttgctg taaagcttga
    71641 tacaccctca tcaactccgt gattttgtac tagactttct atcgttacag gcaatgttcc
    71701 taaactagaa cgtgaagtaa atgccagaag taaagcttca gttgaatttc ttatataagt
    71761 aatgggattt agaccattta aagttataaa aattaaatgt atggtaaata atattgccac
    71821 tgatatataa agagctaata taaactgtaa aacagatact attgagctaa taccttgtga
    71881 agttattgta tttgcaagca gagcaaccac agcataaggc ataaatttaa taacagtcat
    71941 agacacactt acaattattt tgtaagatgc ttctataaaa tctataaatg gttttattgt
    72001 ttcaaagtgt tttttactta atctctttat tgaggtagct ataaatgtag caaatattat
    72061 tgtagctaca atatttccat ttgccatagc cattacagga ttagatggta gtaatcctct
    72121 taaagtatcc acaagagagt ttatttcttt aagttcttga ttttcaacta aagtaggcat
    72181 attagctcct acacctaact tcattatatt tgcaacgata attccaacaa ttgcagctat
    72241 agcagtagta gcaagaagca tacctaaaga tttaaatgtc agagttccaa gattgttatc
    72301 tttcatattt ataattactt ttataatgga taagaaaact aaaggtacta ctaacatttt
    72361 taataagtcc ataaatccag aaccaaatag gctataccac ttgcttactt cttgtagcca
    72421 agtgacttga gtggtatcat taggaaaacc agcaaaagct tgtattatga ttcccaatat
    72481 gagtcctagt actgtagcat atattgttct caatgaaaat tttatttttt tcttttcaaa
    72541 ttgtctaaca ataaagaatg tacctagaag taatattatg aaaaaaatcg ttttaaaatc
    72601 tgtaatcata agaaattgtg ataaaaatga actttccaat attttttctc cttttattta
    72661 aaaataaatt tttctaagtt taaatgatac caatatatta aaaaaatgtc aatattatat
    72721 cacaatttac ttaaatagag taaaataaat tgattttgaa aaatgtgatt aagtatagaa
    72781 aaatagggta taataaatgt ttaaagaatt tgaattgtgg taagaaaata aaaaatagct
    72841 tttataatat ttgatttcaa attaaaatat gttaaataaa taactaaaaa ttgttatgaa
    72901 aaatgtttac atagaatata tatcaaatga aaagcttaaa ataagtgaag aaattaacta
    72961 gacatcaaag gagagataaa atgagagtag taataattgg tggtgttgca gctggtatga
    73021 gtgctgcagc aaaattaaaa agaataaaac ctgagtatga agttgttgtt tatgaaaaaa
    73081 ctgaaatagt atcttttggt gcttgtggat taccatactt tgttggtggt ttttttgatg
    73141 atgctgatga attattagca agaacaccag agaaacttag agaagctgga attgatttaa
    73201 atatatttag agaagtcgtt gaggttgata gtgaatctaa gaaaataaaa gtaaaaaata
    73261 taaaaacaga tgaaatatat gaagattact atgataaatt gatgatagca actggagcaa
    73321 gaagtattat gcctcctata aaaaacataa aattgaagaa tgtttctaca ttaaaaagtt
    73381 tatatgatgg agaatatcta aaaaaacttt taagtaatga agataataaa agagtgacaa
    73441 taataggagc tggttttata gggttagaag cagttgaggc atgtaagaaa ttaggtaaag
    73501 atgtagatgt aattcagtta gaagatagaa tattgccaca agtatttgat aaggagatga
    73561 cggatgtatt agaagaagaa ataaatagac ataatgttaa tttgcacttg gatgaaatgg
    73621 ttgtagaact ttgtggagaa gataaagtag aaaaagttat aacaaacaaa ggggaaatag
    73681 atacagatgt agtaataatt gctactggtg tgagacctaa taccgagttt ttgtcaaata
    73741 ctaatataaa aatgctaaaa aatggagcta tagtagttga tgaatatgga agaacttctg
    73801 tagaagatat atactctgct ggagattgtg caactataaa gaatatagta agtaatgaaa
    73861 atgtatatgt tcctttagct actggagcta ataaattagg taggatagta ggagaaaacc
    73921 tagcaggaag agaagtatct tatcaaggtt cactatcttc aagttgtata aaaattatgg
    73981 atatggaggc agcatcaact ggaattacag aaaagcaagc taaagattta ggcataaatg
    74041 tcaaatctaa atttatttct gattataatc aaactcatta ttatccagga agaaataaaa
    74101 tatatgtaaa acttatttat gatgcagata caaaagttat tttaggcgga caagtggctg
    74161 ggtttaagga tgctgtccaa agagcaaatg tattggcagc tgctatcttt ggaaaaatga
    74221 ccacaagtca acttggaatg ttagatttat gttatgcccc accatttgca agaacatggg
    74281 atgttttaaa tgtagctgga aatgtgtcta aataatattt agattatagc taatatagtt
    74341 gacaagcaat taagggaatg aatttaccta aactattttt atcatggtaa aattcatccc
    74401 taaattttta ttccaaattt ttagaaataa ggattccatt aaattattca tcaaaattta
    74461 aacgcaagct taatctatct tctccaagaa tagtattttc aaaaacatta gtagcatttt
    74521 ctaaatacat actaggtatg tctaaagaag gactaaaatg ggtcagtaaa agttgtttga
    74581 catttccaag ttttgcaaga ttagcagctt ctctaaaagt catatgtttg tttctaacag
    74641 cttttgatat atctaaatca tcaccataca tggcttcaca tataaataaa tcactatctt
    74701 ttatgaaatc tggtattgat tctataggtc ttgtatcggt tgtaagactt atcttaactc
    74761 cctttctcaa ttctcctaag accatatctg gagtgtattg ttttgaattt aaaactatat
    74821 tttgaccttc ttggagtttg ttccataata ttttaggaac ttcgttttta gttgccttat
    74881 ctatatcaaa tttagggttt cttctaaaat taaaactgta tcctaaacac tctatagagt
    74941 gttctaaact gattgttgaa atttctaaat ttcttaaaac tttattatct aaagaaaaat
    75001 tgccttgagg gttttctata atttttaaag tgtatggtac atattctact aaatttctca
    75061 tagaacgtat acaatcgact attccaactg gaccaactat agttaaatca cttgtacgac
    75121 cactattccc aattgttgat aaaagtccta aaagtccaaa tatatggtca ccatgtaaat
    75181 gggttataca aatcaagtct atatctttaa agccacattt ttttagcttc atagatacct
    75241 gagtaccttc accacagtca attagtattt ttctaccttt atagtttata aatacagagg
    75301 atagaaatct gtttggcata ggtacatttc caccacatcc aagtaaagtt aaatctatca
    75361 ttttttcccc tttctaaaat taacacaaat ctgttgtttg tttttattat gatatcctat
    75421 tataattatt ttaacattaa atataacaat aaatgtgtat ttgagtcaag aaatattatc
    75481 aaataaagtt tttatatagc aatgtataaa aatttggaga acgaaaagtg aaaattatat
    75541 ttaggagtat ttaaaggagg aaaatttaat gaaagtatta aagaaaatta ctattttgtc
    75601 attgattaca ttaaccttag ttggttgtag taacggagaa gataaaaaag tggttgaagg
    75661 ttctaagaaa attcaaaatt ctaaaaaaga tgaacagcct ataatagtac ataaagatgc
    75721 aaatatattg aaagataggt atgagccacc aaaaggattt aaaagagttg atgtagaaaa
    75781 aggtagtttt gaatcatttc ttaggaatac taagctaaaa aattatggag agaaagtaaa
    75841 gtattatgat ggaagaatta aggaatcaaa aggtatttat gatagtgtat ttgatgttga
    75901 tattggcaat agagatttgc atcaatgtgc agatgcgatt atgcttatga gagcagaata
    75961 cttgtatcag aataaactat atgatgaaat aagttttgat tttgttgatg gttttaaggc
    76021 gaagtattca aaatgggcac aaggatatag aatttcagta aaagatagtg gttcaagctg
    76081 gtataaagca actgaatatt caacatctta tgagagtttc agaaagttta tggatatagt
    76141 gtttgcatat tcaggaacgt tatctcttga aaaagaattg gagcctgtaa aagttgagga
    76201 tatgaaaata ggagatgtgt ttatagttgg tggaagtcca ggacatgcaa gtataattat
    76261 ggatatggca gaaaatgaaa agactggtaa aaaggtattt atgatagccc aaagctatat
    76321 gcctgcacaa caaacgcaac ttcttattaa tcgtaaaaat ccaaatttga gtccttggta
    76381 tagtttagat tttgaaggtg atttgacaat acctcaatgg acttttaaaa gagaccagtt
    76441 gaaaagattt taaaataata attttatata ataaaagaaa aatatagatg tgaaaaaatg
    76501 taattagatt aaaactaatt ggatatggac aaaattaaat tgatagataa atattaaaaa
    76561 ttacactaat caatcttact atagtttaat atttatctaa aaagttttat gtaaaatata
    76621 aattttatat taaagctaaa actaatttga ggaggctaat ttatattgaa gattagaagg
    76681 tatttaattt tggtaattat aattctaatt acaacaagtc agagttttat ttcttatggg
    76741 ctagagcgat ttgaagaaat aaccattttt cacactaatg atatacatgg aagatatgct
    76801 gaaggtgatg accatataca aataggaaat ctagccacat tgaaaaaaga aactccaaac
    76861 tcaattttag tagatgcagg agattgtttg catggacttc caatagtaaa tatggataga
    76921 gggaaaagtg caattgaatt aattaaatgt gctggatatg actatattac tcctggaaat
    76981 catgacttta attatggaaa agatagactg tttgagttat ctaaaagtgc taatttagga
    77041 gagaatactt taaaattttt atcatcaaat atttttgaaa atggaaaaaa agtttttgat
    77101 agtaatgata taaaagaaat agatggaata aaaataggat tttttggact ctcaacccag
    77161 gaaacaaaga acaaaactgg atttaaaaat gtggaaggat tagagtttaa aaatcctata
    77221 gaaagtgcaa cagaacaagt aaatgaatta aaaggaaaag gtgccaatgt aatagttgca
    77281 atatgtcata ttggtacaaa tagtttaagt aagccaaata gtatagatat agcaaatgag
    77341 gttcaaggaa ttgatttgat tattgatgga cacagccaca ctaagtttga aaatggtaaa
    77401 caagtgggtg atacattgat tgtaagtgca ggacaatatt tagaaaatat tggcgagata
    77461 aaactaactt tggatactaa tgatgtagaa aatataaaaa tagaaaataa atcagttaga
    77521 ttaattggaa aagaagaagc attaaagtat aagcttgact acgttgtaag taaaaaggtt
    77581 gatgaaataa aagaacaaca agaaaaaata ttagataaag ttataggtgc aactacaaat
    77641 actctagatg gttcatatga aaatgtaagg acaaaagaaa ctaatttggg taatttaata
    77701 agtgacattt tactagataa aactaaggct gatatttctt tatttaatgg agggaatatt
    77761 cgagatacga tagaaaaagg caatataaca agaagagata ttgtagatgt atttcctttt
    77821 agcaatacta tagttaccaa agaacttaca ggagcacaga ttaaagatgt attggagcat
    77881 ggagtaaaac tttatccaga aaaaagttca gcctttttgc aagtgggagg aatttcatac
    77941 tactttaatc ctaaacaaaa agaaggcgaa agaataacaa gtattcaaaa agaaggaaag
    78001 ccattagatt taaataaaaa gtatgtagtt gcaacgaatg attatatagc ctcaggtgga
    78061 gatgaatttc cttgtttttc aaaagagcca atactaaagg aatttggaaa tttagagagt
    78121 gcagtcattg aatatataga gtacaaaaaa gaaatatcaa aaaatgtaga tggaagaatt
    78181 ggtattaaat ctaaagatga gttaataagc aagaatcatg agagtgattt gatattaagt
    78241 gaaaatgaaa aaaatatcaa tgataatgaa gagaatctat ctaataatat aaaaagctct
    78301 gatagtgaca aaaataaaag cttagataaa acaagtgcta gagaaagttc taatcaagga
    78361 atatctaaaa gagaagctaa agaaaaatct cctaaaacag gagatttagg tttttcaaat
    78421 agtataatta tatttatagt ttcaagtaca ttgatatgtt tattgaattt taatcaaaaa
    78481 gagttaaagg ataaaaagtc aaaataaaaa ttaatgagca aaattagtag atagtaattt
    78541 aattttagat aatagtaaac agcaaaggaa attagttata taaatactaa tttcctttgt
    78601 tttatgcttt aacatgatta tttttaaata aaattgtatt ttatgaaaaa taattacact
    78661 aaatggcata gtattatggg gatttttagt ttttattcaa gtaaatgaaa tcatattaac
    78721 aacttctgat atatttacaa attgataaaa aaatgatttt attagtatga tataatttag
    78781 ctagtatata tgatgatgga ggatataggg atgaataata tattactttt ggaagatgac
    78841 aaatctttaa atagaggaat tagttttaaa ttaaaaaaag aaggatacaa tgtttttagt
    78901 gcatttggta tagaagaagc aaaaaatatt ttcgcaaaag aagagatatg cttaattatt
    78961 tccgatatag gtctacctga tggtagtggt tttgactttt gtgaggagat tagaaagaaa
    79021 agtgatgttt acataataat gttgacagct cttgatgaag aggtggatat tgtcacagga
    79081 tatgatttag gtgcagatga ttatatcaca aagcctttta gcttgatggt attaatatca
    79141 aaagtgaatg cgcttatgaa aagagtaaat acagtaaaaa attatactct attagtttgt
    79201 gatgatttat tcttttatta tatagaaaat aaattaatta taagaacaga tgataaggaa
    79261 gaagagataa ttttaagtaa gacagagaca aaactattaa aatatttgat ggaaaattct
    79321 atgcagacat tgactaaaga acaactgtta gaatctttat gggatagtag tggtaatttt
    79381 gtagatgata atacgattgc agtaaatata agaagactta gacaaaaggt tgaaaaaaat
    79441 ccatctgaac ctaaatatat aaaaacagta agaggggttg gatatatgtg gggagaaagg
    79501 agtataaaaa aatgctaaaa aatatgaacc tcaaagatgg tttaagtgtg aaagatgatt
    79561 atataatgag aagagttatt gtatattctg ttttatctgt actaatagta acccttgtat
    79621 ttatactttt tgaatatagc agattacata aattgtatga acatcaaata aaaaatactc
    79681 aaaatattgc tggaatattg attgaaaaat atcctaatga tgaaatagat atagtaaatt
    79741 ctatttataa ttccgattat agtaaggtgt ctactggaga aaaggcattt aagaaatttg
    79801 gctatggatt ggaaaataaa atgtcaaatg ataaaaattt tagtttatac ttaaaatctt
    79861 tttttaagga atcatttttt atttttttaa tgatgtttat agtagttata ggtataatat
    79921 attattttat aagatacata aataaaagat tgagtaaaat ttattttata gtagataaga
    79981 tggcacaaga aaactacttg aaggacacta ctgagtcaga agaaactggt tatctagtag
    80041 aatataatga gtattttaaa gaaggtacat ttagtaagat aaataactgt ctatatgagc
    80101 ttaatagaag tttaaagata aagtttatta aattagaaaa agaaaaagaa agtgtaaaat
    80161 cattagtaac agatatttct catcaattaa aaactccttt agcatcctta aaattataca
    80221 atacattact tatagaagaa aaattagaag aagatgaagc caacgagttc ttattaacca
    80281 ataaggcttc tataaataaa ttagaaaatt taataaattc tttagtgaac atatcaaggt
    80341 tagaaattag catgataaac ataaaaaaag aagataatga tataaaaaat actattctaa
    80401 atgcagtaaa aagtgttacc cctaaggcta agagcaaaag tataacatta aatttaaatg
    80461 aatttaacag tagaattata ccacatgata aaaagtggac tgaggagagt atttttaatg
    80521 tattagataa tgctgtaaag tacacacagg taaatggaga aataaatata tctgtagaag
    80581 aaactgctaa tttctttaaa attataatag aggataatgg catagggatt gaaaaaaatg
    80641 agtttaataa tatatttaaa cgtttttata gaggttctgc tgatgaaatt gaatctgtag
    80701 aaggtagtgg ggtaggattg tatttaagta gaaagatttt agaagaacaa ggtggaaata
    80761 ttatagtttc ttcaaaagta gggataggga gtaagttttc tttgtttctt acaactatgt
    80821 aatattaaat gaaaggaaaa tgtaagcctc tacatttatt atataagtat aaacagctcc
    80881 agaaataaaa aattaataaa atatggggta atataactta gaatgagggg ataattttat
    80941 gaaaatacta tatactgaaa atttatcaaa gcattatgga aaaggagaaa acttagtaag
    81001 agctttggac aatgttaact tagaaataaa tgaaggtgaa tttgttgcaa taataggaaa
    81061 atcaggttct ggaaaaagta cacttttaca tatgattgga ggtcttgata tacctacatc
    81121 tgggaaggtg tatatagata ataaaaatat atttacatta aaagaagaag aactagctgt
    81181 gtttagaaga agaaaaatag ggtttatatt tcaaagctat aatttaattc catctcttaa
    81241 tgtatgggaa aatgtagtgt tgccaatcgg tctagatggt agagaagtag atgaatcttt
    81301 tataaaagaa cttttgaaat cattaggact tgaaaataaa catgacgttt taccaaatac
    81361 attatcaggt ggtcaacaac aaagggtggc aatagcaaga gcattagcta caagaccagc
    81421 tataatactt gctgatgaac caactggaaa cctagattct aaaacatctg atgaggttat
    81481 gagtatatta aaatctatgt ctaagaagta cagtcaaact ctagttatga taactcatga
    81541 tgacagtata gcccaaatgg ctgatagagt tatattcata gaagatggca gggtgtcaaa
    81601 ggttggtgat aaaaatgatt aatactacta aaatagcaaa aagtaattta aaacaaaata
    81661 aatcaaaaag tattctaata ataatcacta taatactttc tactttaatg ctttcttcta
    81721 ttggaattta tattgttgat gcaggagcat atcaaaaaga aaatactata aagtattcag
    81781 gtaattatca aggtatatta gcaaatgtag atgaaaaaca ggctgatata ttgagtaatc
    81841 atgcagatgt tgaattaact ggtgaaatga atggagtagg tgttgaaaaa ctggaagatg
    81901 attcaaatat ttctctagca tacatgaatg aagatgcttt gaaattaaat agttttgaac
    81961 ttatcaaagg aaaattgcca acaaaagaga atgaaattgt gttagatagt ggagctttaa
    82021 aggcacttgg ttataaaaat aaagacttag gtgaaaagat aaaaatatct tataatgact
    82081 ataaaaatga taaaaaaatt gaaaaagagt tcgttataag tggaatctta aaaactagcg
    82141 aaatatctga agcaggtaaa tattattatg ctattatatc agaattatat atgagaaata
    82201 ctagagatat gtcacaagaa gattttaata tttatgtaaa atttaatgat aaaagtaatt
    82261 tatcaataga gcaagcaaaa gaaaaattag ataaaattgc taatgatata ggacttgata
    82321 ctattaatac tgctgtaaat gaaaattata taaatgcttt aaaaccagat atggaaacga
    82381 ttatgggtgg aggttttgta ggattagtaa ttgtattatc tagtatttta gtaatataca
    82441 atatatttta tatttcaata gttacaaaag ttcaagaatt tggaaaactt agagcaattg
    82501 gtgcaactaa gaaacaaata aaaaatatag tgtttaagga agggtttata ttagccggaa
    82561 tagcaatacc aataggaata attttaggct atgtacttgc aaatattata ataaaatcat
    82621 ttatggatat agatgtaaaa tcatcacgat taccagttat attatcggtt gtggtaataa
    82681 gctttatatc tgttgtttta tcacttttaa aaccaatgaa agtagcatca aaagtatcca
    82741 ttgttgacgc agtaagatat acaggaaata aaataagtaa taagagtaag agaaaaggat
    82801 ataaaaatat aaatctaaag agattatcac atgccaattt agaaagaaat aaaaaacgta
    82861 cttacatgac attggcatca cttatactta gtggaactat atttataaca gtatcaactg
    82921 ctttagaaag ttttgatgct gagaaaatgg caagagaaca ctttccttat gatatagaag
    82981 ttagactatc tggttatgaa atgaacagtg ataaaaatcc taaaaataat ttgaatattt
    83041 tacaaatgga taatcctcta agtaaagatt tttttaatca aataaagaac atggaaggaa
    83101 ttaaaagaat agaatctgca agaagtgtaa aaattggtat ggaggactat gatgttgaat
    83161 ttaagtatga ccttttacaa agtataaatg aaaatgatgt aaaatcatta aacaagaatc
    83221 taatagatgg aaaaataaat cttgaaagac tgcaaactgg agatgaaata gtaattactc
    83281 atgttgatac agcaaaagaa atgggagtaa aagcaggaga taaaataaga ttaactttat
    83341 atgatggaga taaaaagata aaaaaagaat ttaaagttca agcaatagct atgggggttc
    83401 caagttttgg tatagggaag gattttattg atagaacttt aaaatacgat tcaactagta
    83461 gcttgggaat atatacagaa gaaggaaagt atcaagaaat caaagatagt atcaagaaga
    83521 ttgctaaaaa taatggattt ttagagactg attttataga tagtagaatt gagtcaaata
    83581 aggctgttat ttcatttata aagataatgg gatacacgct aacaggcata ataggtgtga
    83641 ttggatttat gaatcttgtc aacacaatga taactagcat agttactaga aaaaaagaac
    83701 ttggtatgct tcaagctatt ggtcttacta ataaacaatt agtgaaaatg cttaattcag
    83761 aggcaatgta ttacacttct ggaatgatga taggaagtat tttatttgga ggtatattag
    83821 ggtatattgc tgttatattt ctaaaaaaga ctggattatc ttatgcaaca tattctttgc
    83881 caatagtacc aatcttgttg atgattgtgt gtattcttat agctcaattt ataacaactt
    83941 atttgatagg acgaagtttt aataaagaat ctcttattga tagagtaaga tacagtgaat
    84001 aaaatgcaaa tatttgtggt tagtttaact agcaaaaagc atataaaaaa tatagttaaa
    84061 gagattcata attaaatagg ttaaagcata gtacagagca aacaatttaa acggatgttt
    84121 gctctgtatt ttattatgta atcaataata tatctaatat actgatatta ttcatgttag
    84181 aaaatgtatc ggtacaattc taaaaaagta taaaattgta ccatataaaa tgaaaatttt
    84241 gtataataat cgtatagaaa ataaatagga gctgatatat atgaataaga agattaatta
    84301 tgcaccagga ccaactgaaa ctagggaaaa tgtaagatta gcaagagcag aaaaaacaac
    84361 aaatccagat atagatattg attttgttga attttataaa aagacatgcg agaagtttgg
    84421 caatatagtt ggaacaaaaa acgatgttta catattgagt ggtgaaggaa tattagggct
    84481 tgaagcagca tgtgcatcac ttaccgaaaa aggagataga gtacttgtaa ttgacaatgg
    84541 tatatatgga gaaggtttta aagattttgt aacaatgtat ggtggggagt atgtgctttt
    84601 ttcaagtgaa tatactaaaa gtatagatat tgatgaattg aaagcatttt tagatgagga
    84661 tagtaatttt aaatatgcaa cagtagtgca ttgtgatact ccaactggcg tattaaatga
    84721 tgtaagcaaa atatgtccat tacttaaaga atatggaata ttaactgtag ttgattctgt
    84781 agcaggtatg gtaggagaaa gattaagtgt ggatgaatct aaaatagata taatattagg
    84841 tggttcacaa aaagctattt ctgcaccagc aggacttact atagttggaa taagtcaaga
    84901 tgcaaaaaat tgtataaaaa atagaaaaac tgatgtaata ggtttttatt gtaatttaaa
    84961 tatatgggaa ggctattatg aaaaaaaata cttcccttat acaatgccaa taagtgacat
    85021 aatggggctt gataaagcac ttgataatat attagaagaa ggaatagaaa atgtattaga
    85081 tagacatgaa aagatagctt atagtgttag aaaatctatt gaggaatatg gtctagaact
    85141 atttttagaa gaaggatatt ctaatacagt cacagctata aaaattcctg aaagtatagg
    85201 agctttaaaa cttactgatt atatgcttaa aaattataat acacttgttg caacatcact
    85261 aaatcaatat atggatacta ttttaagaat aggtcatatg ggagagaatg caaatctaaa
    85321 taaaatagag catgtactaa atgtcttgga taaaagttta agtgcattag gattcaaagg
    85381 aaatgaaaat ttgttgaatt tatttaataa gtattatttt taatagatag ggggatatag
    85441 tatggaagtt acagctaagc aaaaatttac aacgaaagac atggtggaaa cctcactatt
    85501 aatagcatta gtatttattg caactaaatt tataaatata agattaccaa tatctataaa
    85561 tggtgggctt gtgcatttag gaacagcaat gttgttcata tcagcaatag tatttggaag
    85621 taaaaaaggt gctttatcag gagctattgg tatgtcactt tttgatttaa tatctgggtg
    85681 gactttatgg gcaccgttta cctttatagt tagaggagtt atgggttatt tacttggaaa
    85741 gattgcatgg gcaaatggta ataatgggaa taatttttta atcaatgtaa taggaatatg
    85801 tgtctcatca atttggatgt tatttggata ttatataaca gaagttatac tttatggtaa
    85861 ttttatagta cctcttactt caataccagg taacttaatg caagtattga taggtcttat
    85921 aatagcgctt cctatttcta aggtattgaa aaaatgtata aaataaatat aaagtgaact
    85981 aaaatttatg atagcataaa ttatactgta taatattaag atggagtaca taattaaaaa
    86041 attttagtat agaggttagt tcacaatgtt atcagttaca agatattcaa tcaaaaatgt
    86101 tcgtttaaag ccgtgggtaa agtttatttg gtattttgaa acaaaatcaa atatactgtt
    86161 aaataataag ttacttccta cagacagtat agatattatt cttaatcttt ctgatgttat
    86221 ggaatataaa attgaaaatc aagactatac tgctagtaat atgcatttta atggaataag
    86281 ggataaacat ggatttatta ttcaacatgg aaatatacgt gttataggga tttcttttta
    86341 tccatttggt ctctatccat ttttaaagat accaatttca gagtttaaca gacaaattgt
    86401 tgacttagaa gcagtatcag aactatttgc caaaaaattg gaagagtcat taaatccaac
    86461 acaatcagta gaaaaaattg ttttatattt agaagaaatg ttattatcca tattagaaga
    86521 agatttaatt tcaaataaat ctgtaaagct tctaaattca tttatatatg ataatagata
    86581 tagcaatata aaagcatttt gtgataatac aaatataaat attaaaacat tggaaagaat
    86641 ctgtttaaaa tatacagggt atacacctaa gattttaaag agaatttaca gatttaaaat
    86701 ggcaagtagt caacttattt ataattataa agataatgaa ctttttgatt ttatttatga
    86761 aaatgagtac tatgaccaag cacactttat aaaagaattt aaaaaatttt cagggacgtc
    86821 accaattaaa tttattggtg agaataagac gattaaagaa aatataaagt acaactattt
    86881 ataattatac tgtcgatttt ttacaatacc tccaatttat tttttgatat gatataggaa
    86941 aataaattgg aggttttaca tatgaaaatt attacagaaa tagttgagtt taatgtggaa
    87001 gaaaatttat caaaagaaga gtttatagaa attgtaaatg acttagaatt aaaatttcat
    87061 tctattcaat ctggttttat tgatactgag cttttatatg atgaaaagtc tcaaaagtgg
    87121 attatgatac aacattggga atctatagaa gacctcaaga gtgcttctag taaaatgttt
    87181 aaagattctt caactgagaa atttagaaaa gctttaaaga atcaaactgt taagatgaat
    87241 ataataccac aaattaaaag ttggaaatta tagaactgaa tgtaaaagat agttaaatag
    87301 tatcaaacta aattagccaa ataacatttt gtatttaaat tgttatttgg cttttagtgt
    87361 ttactttaat atgagtgtta tatactagaa aaaccaacaa actgttagag tgtggattat
    87421 aataatgtca tatttgggag ctaaaaggct taatactgat ttgtcaatat gtctttttag
    87481 catgttgaac aggtatattg ccatgctttc attattttat ttttttgcct tatactggac
    87541 tacatttgca gtttcctaat atatttggct catatttaaa tgccattatc taaaagtact
    87601 attgctgtac gagaggcaat aggcatttta gaagaaggag gagttgagct aaagtataca
    87661 tcataatctc ttaagttttc tttttttgtg tttcctccaa actctaccat atcagtattt
    87721 aatatcgttt tgtagtttgt attttgaaac tttgaaatat caactgattg tattagatta
    87781 gggtggaaat taaatataaa taaatatttg cccttactgt acaccaaaat ctttttatca
    87841 ttatccatat gtataagttc atgactattt tggataaaaa tatcactgta ttttgtaagt
    87901 tcgagcatag atttatcaaa atttaataat tgtttatact ttaagttgtt atcttctgaa
    87961 aggctccatt gtcttctggc atacttatag ctccaattgt tgccttctcg tggaaaatca
    88021 atccactcag gatgtccaaa ttcatttccc ataaaattta gatatccttc acctgctaga
    88081 gaaaaagtta ttaatttaat taatttaata agagatattg ctctattgat aacatggtta
    88141 tttgagttta tttccatatt ccagtacatt tccttgtcag ctagccaaaa aataattgtt
    88201 ttatcgccaa ctaatgcttg gtcatgggat tcacaatatc ctatattttt ttctccaggt
    88261 cgtctagtag taagttcata ccacattttt cccaaatccc agtcttcatc agataagtta
    88321 gagatagttt ttatccaaaa atcaggtact cccattgcga gtctatagtc aaatccaatt
    88381 ccgccgtctt ttatagggat acacatacca ggcattccac tcatatcttc tgcaatactt
    88441 atcgaattag gtttaatttc ttttattaat tcatttgcaa attggagata tgttatagct
    88501 tcaatatctg tattcatact aaaatatttt tcataactat caaatgaaac tccaagacca
    88561 tggttatgat ataacattga agtcacacca tcaaacctaa agccatcaaa atggtactca
    88621 tttaaccaaa attttatatt tgaaagcaaa aaatgtatta cttcaggttt accatagtta
    88681 aaaagttttg taccccaagc aggatgattt ccctttgaac ctgagtggaa aaattgatgt
    88741 tcacttccat caaactcatt tattccttct aaagtattct ttacagcatg agaatgaact
    88801 aaatccaata aaacagcaat ccccattgaa tgagcagtgt ttatgaggtt ttttaagtct
    88861 tcaggagtac caaacctaga tgagattgca taaaagtttg aaacttggta tccaaaagat
    88921 gcataatatg gatgttccat aatagccata agctgaatgg tattgtatcc agcttttttt
    88981 atcttaggaa gtattttttc agtaaattca ttataagttc caatagattc gctttcagta
    89041 gacataccta tatgacattc atagattagt ggagaagtta tgttttttaa gtcaaaatta
    89101 ttgtcagtcc agataaatgg agtttttggt tgccatattt gtccattaaa tccaccaaaa
    89161 tctttttgaa ttactctttt tatatataat ggtatacggt caaatgtttt tccatttgca
    89221 gtaacttgta cctttacctc tgatttgtga ggtaagctat tttgaccagg aataaatatt
    89281 tcccaattac cagacccaat ttttcttaga ggatgagatt ttctattcca attattaaag
    89341 tcaccaatta gtgacaaact atctgcattt ggagcccatt ccctatagaa gaatccatca
    89401 tttgtctgat gaaatccata gtaaagatga gcatttgcaa aagaactaaa atctttatag
    89461 tttttcaatg tttttgattt catatcctca taatgtttca ttcgcttttt tatatcagat
    89521 tcaaatggtt gtaggtatac atcaatatct aaaattttaa atcttttttg acttttcatt
    89581 gtatttctcc tccataataa atattacatt taaaaaataa tatttatctc atactatctt
    89641 ctctgtataa ttgatatata ttatataatc ctaataaaaa gcttaagcca ccaatgatta
    89701 atttcataat ttacctccct agtatttata cttatatatc gtattcatca aaatttaaaa
    89761 gtttgtttaa aactctttta ataatatcat aatcaaagcc tttataggaa agatgttgag
    89821 aaattttttg atatattttc tttttatctt ctttctttac tctttcatac cttttttttg
    89881 ctagatacat agcattttca aattcagtgt ccttgtctaa ttcagatact gcttcattga
    89941 ttgtacttct attgatacct ttattatata aattctgctt aattctgttt ttgccacatt
    90001 tatttaggtt aacatttgtg ttaacaattt tttgagctaa tacactgtca tttacgagat
    90061 tataactttt aagaaaatct atgaccctct caattatatt ttcatcaaat tctgatgata
    90121 gtttttcttt taattttttt tcagattggt cagcatgaga taaaatattt aatgctttat
    90181 ttttagcttt tatatacatt tcatcatcta aaataggttt taattcttct tcatttattt
    90241 cattcccttt ttttaaatta aatgtataaa caagttcttt aaatatagca ataaaaaatt
    90301 tatcatctac ataaatatta actctatcat catttctttt ttgttgttct atttttgtaa
    90361 ttatacccat aagtcctcct tttttatatg taattatatt aacaaaagca actaataaaa
    90421 tttaacaaaa aacttatatt tgtatgttat attttatcaa aattaagaca aaatagtaaa
    90481 aagttatttt tattaaaaag taaagcagaa tcatgttaaa taattatttt ttaaagtgtt
    90541 ttttagcata taaatataat tatataccca aaaaaacaaa ttataagctt taagaaataa
    90601 aaaataatgg tacaatagta ttataacatt aaaaggagac aaaatatgag aagtgaaaat
    90661 ctagttaaga tggcagagtt gaaaaatact gaaaaactag agaaatttaa tcgccataaa
    90721 ggcaaaatca aaataggtat attgggaggt acttttgacc ctatacacta tgctcattta
    90781 gcaacagcag aatttattag agacaagtat gacattgaca aaataatctt tataccatca
    90841 ggaaatccac cacataaatt atgtatcact acagataagt atgatagata taatatgaca
    90901 cttctagcaa ctgaaagcaa cgaagatttt ttagtttcaa aagtagaaat cgaaagaaag
    90961 aaaaggactt atacaataga tacattaaaa tacttaaaga aaaaatacaa aaatgcagac
    91021 atttatttta taacaggtgc agatgcaatt tgtagtgttg aagagtggaa agatgtaaag
    91081 aaaaactttg agttagctac ttttatagcc gcaactagac caggaattag tttgttaagg
    91141 tcacaagaga ctatagaaaa actaactaag aagtataatg ctgacattat aacagtttat
    91201 gttccatcac tggatatatc gtccacatat ataagggaac agctaaatga aggcaagtca
    91261 atacgttact tagtacccga aaatgtagaa aattatttat atgaaaataa actatatcaa
    91321 tatggagatg attaaatgaa cttagaaaat attaaccaaa gactaaatca aatgctacca
    91381 gtggggaggc ttagccattc aagaaatgtt gcaaaatgtg ctgaaaaatt atgtgagatt
    91441 tatggatgtg acaaagaaaa agcttactta gcaggaatga ttcatgattg tgcaaagtat
    91501 ttaagtgaca aggaaataga ggattatgta aataagtatg aaatatattt agacccaata
    91561 gaggatggaa atcgttcctt gtctcatagt gtaattgggg cgtacatatg cgagtatgaa
    91621 tttgaagtag aagatgaaga tattataaat gcaatcaaat atcatacaac agggagagag
    91681 gacatgtctc ttttagaaaa aataatttac atagctgatt taattgaaga aggaagaaaa
    91741 tttccagttg tagatacatt aagagaatta gcatatggag ggaagcttga tgaagcactt
    91801 ttaacttctt ttaataatac tttaatgttt gtcatcaata aaaaagaaga gatacatcca
    91861 agaacagtta tggcaagaaa ctatctaatt aaagaaaagt tattataaaa aagctatata
    91921 aaggcaaaca tattaataaa tttaaatttg actatgttac aaaatcgtat taatatgtta
    91981 caataactaa gtgtatttta attaggaaag tgaggaattt ttatatgaca gtggaacaaa
    92041 tgacaaaaat agcatatgat gccatagaag ataaactggg tcaagataca gttataataa
    92101 atataggaaa agtttctagt ttgtgtgatt attttattat tactacagca tcttctcaga
    92161 gacaggtaaa agctattgct gacaatgtgg aagatgaatt agcaaaacta ggattagagc
    92221 caagaggtaa agaaggacaa ggaactcaaa cttgggtact ccttgattat ggagacataa
    92281 tggttcatgt atttaatgag gaaaatagag ggttttataa tttagaaaaa ttatggaaag
    92341 atgcacctta tatagatatt gacacattag cataaacatg ataatatatg ttattataat
    92401 tagaaaattt caaaaattat attaaattga atagactaga gcagtaaaag attatatttt
    92461 ttcagagagt tagtggaagg tgagaactaa tattatataa ctttgaactt actagattaa
    92521 aatctattct ccatggctgg attaaaagct atctaagaga gtctatatat gtagtaggct
    92581 aattagggtg gtaccgcgaa gatttatcct cgtccctaaa cgtaagttta gtgacgagga
    92641 ttttttattt tcaaagaatt atttggaaat tataagtaaa taatactaaa taaggtagtt
    92701 atacacaatt aaaaatagga ggcaaaatat gagcgtatat aattttaaag aagtagaatc
    92761 gaaatggcaa aaaatttgga aagataataa tcagtataaa atggatactg cacaaactga
    92821 aaaacctaat tattacacat tagaaatgtt cccttatcca tctggaaaaa tacacatggg
    92881 acatgttaga aattattcta taggtgatgt tgtcgcaaga ttcaaaaaaa tggaaggata
    92941 taatgtactt catccaatgg gatgggattc ttttggatta ccagctgaaa atgcagctat
    93001 aaaacatgga atacatccgc ataaatggac aatggaaaat atagaagaaa tgaaagagca
    93061 attaaattta ttaggtatta gttatgattg ggataaagaa gttgcaactt caactccaga
    93121 atactataga tttacacaag aaatattttt gaagttttta gagcatgggc ttgcatataa
    93181 gaaaaaatca tatgttaact ggtgtccttc ttgtgagact gttcttgcaa atgagcaagt
    93241 tgttcaagga gcatgtgaga gatgtaaagc aacagtatta aagaaagatt tagaacaatg
    93301 gtattttaag actactgaat ttgcagaaga attacttaat gacttagata cattagatgg
    93361 atggccagaa aaagttaaaa caatgcaaaa aaattggata ggtaaaagta caggagcaga
    93421 tttagttttt gatatagatg gaactgataa atctatgaca gtatttacaa ctagaccaga
    93481 cacaacttat ggagttactt atatggtact tgctccagag catgaattag ttaaagaatt
    93541 ggttgcaggg actgaatatg aagcagatgt tgaagctttt gttcaaaaaa tgcatactat
    93601 gacagaaata gaaagaacag cagctgatgt agaaaaagaa ggaatgttta taggtagata
    93661 tgttataaat cctttaaatg gcaagaaagt tcctctatgg atagctaact atgtattagt
    93721 tgagtatgga acgggtgcta taatggcagt tccagcacat gatgaaagag atagagattt
    93781 tgctgaaaaa tataatttag acataattga tgtaataaca gaagataaca aaatgataaa
    93841 ttcagaagaa tttaatggat tagatgcttc agaaggattt gaaggaataa tcgataagtt
    93901 agaaaaagaa ggtagaggaa agagaacaat taattataga cttagagact ggttagtttc
    93961 aagacaaaga tactggggtt gtcctatacc tgtggtttat tgtgatgaat gtggaatagt
    94021 tccagttaaa aaggaagatt taccagttct tttaccaaca gatgttgaat ttactggaaa
    94081 gggagaatct ccacttacga cttcaaagca atttatgtca acaacttgtc ctcactgtgg
    94141 aaaaccagct agaagggaag ttgatactat ggatacattc gttgattctt cttggtattt
    94201 cttaagatat gtggatagca ataatgaaaa tgaaccattt agtaaggaat tagttaatag
    94261 atggcatcca gtagaccaat atataggtgg agtagaacat gctataatgc atttgcttta
    94321 tgcaagatgg tttgtaaagg catttaagag tatgggaatg gtagacttca atgagccatt
    94381 taaaaactta cttactcaag gaatggtact tatggatggt tctaaaatga gtaagtctaa
    94441 agggaataca gtatctccta tggatataat agatgagtat ggagcagata ctgcaagact
    94501 tttcgtatta tttgcagcac caccagaaag agatttagac tggtcagagc aaggtgttga
    94561 tggatgcttt agattcttaa atagggttta tagattggtt gacgagttag cagatgtggt
    94621 taaaaaggat gtagagtttg gagaattaaa ttcccaagat aaggatatga gatatactat
    94681 acactctaca cttaaaaaag ttactgctga tttaagtgaa aaattcggat ttaatactgc
    94741 tatatcagct cttatggaat taataaatga tatgtataaa tataaagagt tagataatat
    94801 aaacgaagca gttataaaag aaggtgtaca aactatagta actataattg caccatttgc
    94861 ccctcattta ggtgaagaac tatggactat gataggtaaa gaaggaagtg tatttgatat
    94921 agactggcct aaatatgacg aaaaagcttt agtaaaagat gaaatagaag ttgttgtaca
    94981 agttaatgga aaagttagag gaaaattaac tgttaactca aatatatcta aagatgagat
    95041 ggaaaaggta gctttagaag atgaaaaaat aaaaggatta gttgaaggta aaactatagt
    95101 taaagttgta gctgtaccta aaaaattagt aaatatagtt gttaaataac tcaaaaatat
    95161 gaacaaaaat ataaatttat aaaataaatg aggctgtctc aaaatagaga taagcctttt
    95221 ttcattgttg aaattacaaa aatagatttg attttataca aaaaaatgat taaagaacta
    95281 aaaagttcat tcttatacac tctaattgtt gttttaaata ttattataat taatgttaaa
    95341 tcgtgttaat gtattaagtg gtatgtaaat tattcagttt ctaaagtgtt gttcatcaag
    95401 gaactgctct aagcttaaac gaaaaaaata taattattgt atttttaaaa ttttttttat
    95461 ataatgaaaa caggcaaaaa aggtgcgtat ctatgcttta tcttaaacac ccagacaacg
    95521 agattcagat tcatataata actaccatgt ttctaaaaag gaacttgcaa aaaagatagg
    95581 cgtttcaact tcccagttga ttaaaattat caccaggaaa acaaggatgg tcagcagtag
    95641 tattctaatg ggtgttgctg atatatccaa gttgggattg tttgaggatg ttatcaaatg
    95701 acttgtgata ggtgcagtag atgtggagat tcctgatacg gatttattct caggggatgt
    95761 ttgcttcagg agatatggag cgtaaccagt ttattgatat ggtaaccatt tttttgtcta
    95821 atttgatgaa agaatcccaa gaataccata cagaagtaag acaggaatta actggtggta
    95881 taaactgata aaggcaaatt taaaaatttt gataggatga ttttaagatt tatcttctat
    95941 tttgtttttt agaaataatt gaaatgttat gagggggtgt gtacaaatgg agactgtatc
    96001 aaataatcaa tcaagtgtag aaattcaact cagtctgttt gaagctatca aagatttatt
    96061 gttaattaat cctattttct tgttgggaat tatcttgatt ggtattttct tagttgtaat
    96121 attcaagaaa aatagtgata ttccaaaggt aaaaacatct attttatcac tggcaatgta
    96181 ttactactta tgtttaacac tatcgcatat tgttggtatc cctacattca gtgaatatat
    96241 aagactgtca cagttagggg aaacgttctt taatccaaac ataaatctta ttccttttag
    96301 tgatggattt agtttgagtt ttattttgaa tattttactt tttgttccat taggtttttt
    96361 atgtccgctt atcagcaaaa cctttgaacg gttgagaaat acattcttga ttggttttgg
    96421 attatctctc tttatcgaaa ctattcagct ttttacgtta cacagagcaa ccgatataga
    96481 cgacttactc acgaatgtaa ttggaacaat aataggctat ttctgcttca aactgattgc
    96541 taaattgcga attgtaaaac tacattcaga tgatgactct atggaacagg attacacagt
    96601 atgtattccg attgccatta taatagttgc ccttatatta ggatttttta gttaagttcc
    96661 aaatagctaa tttgggaatc cagacaatat aacagatagt atgttacctt ttacaggagc
    96721 atactgtctg ttatgttgtc aacatctcat tttatggttt gtgtgtattt tcttgtaaac
    96781 tgaactaaat aattaaatag aagttattag aattagcaat agattccttt ttcaaagaaa
    96841 tctttgattt catcaaggtt atcagttttt ccaagtgcta agataagttt tattctagct
    96901 ttttgacctg gcaagtcccc accaaatata caaccaagat tttttaaatc tctaccagaa
    96961 ccaaagtaac cataactatc gaatactcta cctgaatgac atctagaaac tataactaca
    97021 ggaagtcctt tttctctagc atattcaact ccagaaagca tttgaggagg aatattacct
    97081 atacccattg cctcaataac tataccttta taaccactat caacagcaaa tcttataaag
    97141 tcagcatttt ctcctacata tgctttaaat aaggcaactt tagattctac cttatcagta
    97201 tctataattg ttctatttac aatatctctt gtaaggacaa gttcgttgca gtcaattatt
    97261 cctaatggac cactagttag agatttaaat gtatttagag aaagagtatt tgttttagta
    97321 gcttcagaag ctaataatac ttcattgttt aaaactacaa ggactccttt tcccatagca
    97381 tctttggata ctgcagtaca aactgatgca gataaattac ttgaaccatc atatccaagt
    97441 tcagaactac ttctcatagc acctgtgact attacaggtt tgatgttgtc aattgtaagg
    97501 tctagaaaat aagctgtttc ctctaaacta tctgtaccat gtgttattac aacacctgta
    97561 atatcttttc ttgctaataa atcatttaca taatttttca attccatcat tctataaggt
    97621 gttatgtgag gtcctggaat ttcatcaaaa ttaaaaactt caacatctgc aactttatca
    97681 atgttggtaa ccattgatag tatttgttca cctgataaag ttggtatagc tgctccgact
    97741 ttatcatcta ctgtcataga tatagttcca ccagtaaaaa ctatggcaac ttttttctta
    97801 atactcatac gattctctgc ctttcataaa taaaatttat aattccgata ggattatatc
    97861 aaaaaaagta gttaaggtct acataaactc ttttattcat ataatttaga tatttcagtg
    97921 taatataatt atttcttaat tttttgccat tcaacgatat aaccatttaa tatctctctt
    97981 atggcttttc ctatcttagt ataagcttca tcatatagat ttgctagaga tattctaatt
    98041 gaccattcag ggccatagaa tccatttcca ctaagtaaaa ctactgaata gtcattagct
    98101 aatttataaa gaacatctac tggagatgca gttttactta taaatttaaa taagtcttct
    98161 ccgtagttta atttagccca ttcttcaata tcaaattgag tgtaatatgc agcattgttt
    98221 ttgttttcat taattggaag ctctaaagct tcaaataata gtttttgacg tctatggcag
    98281 atactcatat tgagtttttt gtaggcatct actttgtcaa tcaatgcaaa agcagagaaa
    98341 aacgccattt gtacttgctg tggagtagaa agaccagcag tatggttgag agcaacaagt
    98401 ctgctatcag caacaactct ttccataaat gaaagactag aagggttaag actcatatca
    98461 ctgtaacgct tatctactga tttttttaat tctccagtta aatcatttat tttcttatca
    98521 aaaacatttt tcttatgaag ggcaaatgta ccaagtctcc atcctgtaac tccaaaatat
    98581 tttgaataag aatatactcc aacagtgttg taaggtagtt ttgacattaa ggatgaaaaa
    98641 tcttctacaa aagttccata tacatcatct gatattatca ttaaatcttt attataattt
    98701 tcaattacat ctattagatt attacaagat atttcatcca tagctataga agcaggatta
    98761 ttaggattaa caacgaataa agctttaata gatttgtcac gaagtttctc taattctttt
    98821 tttgtatatt gccatgtatg agcacctttt tcatcaactt cattagcatt tatatttacc
    98881 actttaaagt cgtaacgagg aaggttaggt atttcaagat aaggtgtaaa tattggagtc
    98941 attaaggcta ttgtatctcc tttttttaga agttcatttg ccattaatga atcaaatata
    99001 tagcacatag cagctgtagc accttcaaca gcaaaaattt ctacatcacc atatttacct
    99061 gatatatcat atttcatttc ttgaactagg taatcgtgta ctattttttc catatgaggt
    99121 aacattctat ctggaagtgg atagttatca ccaataattc catcagctag ttcatgaaca
    99181 aattcatctc catcaaatcc aagttcattt ataccaaagt ttataatatc tctagctaaa
    99241 tatgctccag gcatatctat attttcattt ataaatttaa aaaatctttc tttaataccc
    99301 tttttttgag gcattccagc caaatgacct aaatcccaat tagaacgagt ttcagtaata
    99361 gcgaaatgac caaaagtaaa aaaggcttct ctagcagttg aacaagtcca gtttggattt
    99421 ccacgacctg catcaagtaa ttctctgtta ttttcttttg cagtgtattt tgcaatatct
    99481 attaatttgt ccttaaattc aaaagggctt atttttccat atatgttttt gatttcttta
    99541 taagtatgat ttttcatgtt aaattcctcc ttatgtaata agtttcacat ttttataata
    99601 aaataaacaa gttgcaaaaa tgattatact ttaattataa taggtttata gaaaaagtaa
    99661 agtatgaaat taaaataata actctattta gccttattaa atatatgtta aaataaaaaa
    99721 taccttttaa taaaaaatga ttgttatata aaataaatat tcaatttaat tatcacctta
    99781 gtttttttat tgtattttat tatatatgta tagttttcta attttgaata aaaataaagt
    99841 aaaactttct tttatattga agttgtttag taagacatgt attttattaa tttattaatc
    99901 ttaataatgt taaataaaat caaaaaaata gattttgggt aaataaaata atataaaata
//
LOCUS       DAEQJM010000006        97300 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.006, whole genome shotgun sequence.
ACCESSION   DAEQJM010000006 DAEQJM010000000
VERSION     DAEQJM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 97300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97300
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.006"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..491
                     /locus_tag="KRQ43_000515"
     CDS             <1..491
                     /locus_tag="KRQ43_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HBH2740888.1"
                     /translation="DISSSADISVIKLANKTEACVEEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVILLRGIIKSTCLDRLTNI
                     AEVTSTTPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCCCNCCKNDF
                     WC"
     gene            948..1295
                     /locus_tag="KRQ43_000516"
     CDS             948..1295
                     /locus_tag="KRQ43_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH2740889.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(1445..2494)
                     /locus_tag="KRQ43_000517"
     CDS             complement(1445..2494)
                     /locus_tag="KRQ43_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2740890.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWVQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            2880..3614
                     /locus_tag="KRQ43_000518"
     CDS             2880..3614
                     /locus_tag="KRQ43_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH2740891.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(3756..4247)
                     /locus_tag="KRQ43_000519"
     CDS             complement(3756..4247)
                     /locus_tag="KRQ43_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH2740892.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            4596..4979
                     /locus_tag="KRQ43_000520"
     CDS             4596..4979
                     /locus_tag="KRQ43_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740893.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKVVLKSPEYIGSHPKKPGKSVEFIKKIDNYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNNGRVKQYDG"
     gene            5485..5868
                     /locus_tag="KRQ43_000521"
     CDS             5485..5868
                     /locus_tag="KRQ43_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH2740894.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            5870..6220
                     /locus_tag="KRQ43_000522"
     CDS             5870..6220
                     /locus_tag="KRQ43_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740895.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(6314..6772)
                     /locus_tag="KRQ43_000523"
     CDS             complement(6314..6772)
                     /locus_tag="KRQ43_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740896.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(6817..7605)
                     /locus_tag="KRQ43_000524"
     CDS             complement(6817..7605)
                     /locus_tag="KRQ43_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH2740897.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(7744..8181)
                     /locus_tag="KRQ43_000525"
     CDS             complement(7744..8181)
                     /locus_tag="KRQ43_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBH2740898.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            9003..9512
                     /locus_tag="KRQ43_000526"
     CDS             9003..9512
                     /locus_tag="KRQ43_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740899.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDSLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVIVIVFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            complement(10423..11223)
                     /locus_tag="KRQ43_000527"
     CDS             complement(10423..11223)
                     /locus_tag="KRQ43_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2740900.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(11418..13016)
                     /locus_tag="KRQ43_000528"
     CDS             complement(11418..13016)
                     /locus_tag="KRQ43_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH2740901.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELNISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIIW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            13344..13520
                     /locus_tag="KRQ43_000529"
     CDS             13344..13520
                     /locus_tag="KRQ43_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740902.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     SILEKELNISKANT"
     gene            13694..14824
                     /locus_tag="KRQ43_000530"
     CDS             13694..14824
                     /locus_tag="KRQ43_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH2740903.1"
                     /translation="MNNFEIKTRIKFGEGSLKVLQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKSIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSDTAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILNNIK"
     gene            15065..15415
                     /locus_tag="KRQ43_000531"
     CDS             15065..15415
                     /locus_tag="KRQ43_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH2740904.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKRD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            15423..15872
                     /locus_tag="KRQ43_000532"
     CDS             15423..15872
                     /locus_tag="KRQ43_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HBH2740905.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDDIGLEKLFKYLEKSKNIDEV"
     gene            15974..16549
                     /locus_tag="KRQ43_000533"
     CDS             15974..16549
                     /locus_tag="KRQ43_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH2740906.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            16542..17951
                     /locus_tag="KRQ43_000534"
     CDS             16542..17951
                     /locus_tag="KRQ43_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HBH2740907.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSNENGTEVLITIPTQINI"
     gene            18135..19568
                     /gene="eutA"
                     /locus_tag="KRQ43_000535"
     CDS             18135..19568
                     /gene="eutA"
                     /locus_tag="KRQ43_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBH2740908.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQTIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSVDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            19586..20950
                     /locus_tag="KRQ43_000536"
     CDS             19586..20950
                     /locus_tag="KRQ43_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HBH2740909.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFYKDGKLTELAGDAS
                     VLLG"
     gene            20963..21844
                     /gene="eutC"
                     /locus_tag="KRQ43_000537"
     CDS             20963..21844
                     /gene="eutC"
                     /locus_tag="KRQ43_000537"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HBH2740910.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKTTEVVVDNNAFI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSQETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            21864..22517
                     /gene="eutL"
                     /locus_tag="KRQ43_000538"
     CDS             21864..22517
                     /gene="eutL"
                     /locus_tag="KRQ43_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBH2740911.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEIAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            22528..23229
                     /locus_tag="KRQ43_000539"
     CDS             22528..23229
                     /locus_tag="KRQ43_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH2740912.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRIDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEITDNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            23232..24701
                     /locus_tag="KRQ43_000540"
     CDS             23232..24701
                     /locus_tag="KRQ43_000540"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HBH2740913.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNIPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            24797..25084
                     /gene="eutM"
                     /locus_tag="KRQ43_000541"
     CDS             24797..25084
                     /gene="eutM"
                     /locus_tag="KRQ43_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HBH2740914.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            25211..25972
                     /locus_tag="KRQ43_000542"
     CDS             25211..25972
                     /locus_tag="KRQ43_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HBH2740915.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLEDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            25985..26614
                     /locus_tag="KRQ43_000543"
     CDS             25985..26614
                     /locus_tag="KRQ43_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH2740916.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            26656..27381
                     /locus_tag="KRQ43_000544"
     CDS             26656..27381
                     /locus_tag="KRQ43_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HBH2740917.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEILEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            27394..27666
                     /locus_tag="KRQ43_000545"
     CDS             27394..27666
                     /locus_tag="KRQ43_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBH2740918.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            27659..28210
                     /locus_tag="KRQ43_000546"
     CDS             27659..28210
                     /locus_tag="KRQ43_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH2740919.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYVVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            28222..29313
                     /gene="eutH"
                     /locus_tag="KRQ43_000547"
     CDS             28222..29313
                     /gene="eutH"
                     /locus_tag="KRQ43_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH2740920.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NSGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLRKENV"
     gene            29315..29788
                     /locus_tag="KRQ43_000548"
     CDS             29315..29788
                     /locus_tag="KRQ43_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HBH2740921.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(29908..30009)
                     /locus_tag="KRQ43_000549"
                     /pseudo
     CDS             complement(29908..30009)
                     /locus_tag="KRQ43_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            30304..30825
                     /locus_tag="KRQ43_000550"
     CDS             30304..30825
                     /locus_tag="KRQ43_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2740922.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            31204..32379
                     /locus_tag="KRQ43_000551"
     CDS             31204..32379
                     /locus_tag="KRQ43_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2740923.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQAYGVDVKVTHTGGIGPVINDEEAVKMSKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            32414..33952
                     /locus_tag="KRQ43_000552"
     CDS             32414..33952
                     /locus_tag="KRQ43_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH2740924.1"
                     /translation="MQGALKENKKKSGGGFLGWIERVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQVI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            33984..35186
                     /locus_tag="KRQ43_000553"
     CDS             33984..35186
                     /locus_tag="KRQ43_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH2740925.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFIQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     SEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     IWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(35365..35964)
                     /locus_tag="KRQ43_000554"
     CDS             complement(35365..35964)
                     /locus_tag="KRQ43_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2740926.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            36133..37491
                     /locus_tag="KRQ43_000555"
     CDS             36133..37491
                     /locus_tag="KRQ43_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740927.1"
                     /translation="MSNIITNLIESVFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            37484..38116
                     /locus_tag="KRQ43_000556"
     CDS             37484..38116
                     /locus_tag="KRQ43_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH2740928.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSKIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            38445..39602
                     /locus_tag="KRQ43_000557"
     CDS             38445..39602
                     /locus_tag="KRQ43_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2740929.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     FNSEEIVYFTPKGKSYHSIKNCSGLSRSKKILSGTIEESKKNDPCDICYGK"
     gene            complement(39750..40385)
                     /gene="lexA"
                     /locus_tag="KRQ43_000558"
     CDS             complement(39750..40385)
                     /gene="lexA"
                     /locus_tag="KRQ43_000558"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBH2740930.1"
                     /translation="MYLDLTEKQVLILEFIKSQITLKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(40489..41616)
                     /locus_tag="KRQ43_000559"
     CDS             complement(40489..41616)
                     /locus_tag="KRQ43_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH2740931.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(41938..42783)
                     /locus_tag="KRQ43_000560"
     CDS             complement(41938..42783)
                     /locus_tag="KRQ43_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740932.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(42813..43184)
                     /locus_tag="KRQ43_000561"
     CDS             complement(42813..43184)
                     /locus_tag="KRQ43_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH2740933.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIEDACKILSCNGYEVE"
     gene            complement(43337..43597)
                     /locus_tag="KRQ43_000562"
     CDS             complement(43337..43597)
                     /locus_tag="KRQ43_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HBH2740934.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(43786..44730)
                     /locus_tag="KRQ43_000563"
     CDS             complement(43786..44730)
                     /locus_tag="KRQ43_000563"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HBH2740935.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(44751..45605)
                     /locus_tag="KRQ43_000564"
     CDS             complement(44751..45605)
                     /locus_tag="KRQ43_000564"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBH2740936.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKELLY
                     QILAMHKK"
     gene            complement(45620..46981)
                     /gene="accC"
                     /locus_tag="KRQ43_000565"
     CDS             complement(45620..46981)
                     /gene="accC"
                     /locus_tag="KRQ43_000565"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBH2740937.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(46997..47449)
                     /gene="accB"
                     /locus_tag="KRQ43_000566"
     CDS             complement(46997..47449)
                     /gene="accB"
                     /locus_tag="KRQ43_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBH2740938.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(47719..48165)
                     /locus_tag="KRQ43_000567"
     CDS             complement(47719..48165)
                     /locus_tag="KRQ43_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740939.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            48440..48718
                     /locus_tag="KRQ43_000568"
     CDS             48440..48718
                     /locus_tag="KRQ43_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740940.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(48847..49593)
                     /locus_tag="KRQ43_000569"
     CDS             complement(48847..49593)
                     /locus_tag="KRQ43_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740941.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLDFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(49722..50366)
                     /gene="trmB"
                     /locus_tag="KRQ43_000570"
     CDS             complement(49722..50366)
                     /gene="trmB"
                     /locus_tag="KRQ43_000570"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBH2740942.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(50504..50824)
                     /locus_tag="KRQ43_000571"
     CDS             complement(50504..50824)
                     /locus_tag="KRQ43_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HBH2740943.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(51277..51702)
                     /locus_tag="KRQ43_000572"
     CDS             complement(51277..51702)
                     /locus_tag="KRQ43_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012201185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH2740944.1"
                     /translation="MHDELKIKMYSFTMDCKDPHELAKFYAALLNWEIAFYNEEYACV
                     GAPGTNQGTYPGITFQRNSEYKPPVWPEKPESQQQMAHMDFAVNDLEEAVQYEIHCGA
                     TIAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(51855..52316)
                     /locus_tag="KRQ43_000573"
     CDS             complement(51855..52316)
                     /locus_tag="KRQ43_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH2740945.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(52354..53187)
                     /locus_tag="KRQ43_000574"
     CDS             complement(52354..53187)
                     /locus_tag="KRQ43_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740946.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCMQLKNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMYICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(53460..54146)
                     /locus_tag="KRQ43_000575"
     CDS             complement(53460..54146)
                     /locus_tag="KRQ43_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2740947.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALVGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(54161..56638)
                     /locus_tag="KRQ43_000576"
     CDS             complement(54161..56638)
                     /locus_tag="KRQ43_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH2740948.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDVLTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEMTENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIENVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDVVMIQIRDLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKKRSIAMYKSIGLSDK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(56858..58261)
                     /locus_tag="KRQ43_000577"
     CDS             complement(56858..58261)
                     /locus_tag="KRQ43_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2740949.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIIFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLTLANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGSK
                     FVGGKSIVFSIIGIIFLIILISGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNKYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            58760..59620
                     /locus_tag="KRQ43_000578"
     CDS             58760..59620
                     /locus_tag="KRQ43_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH2740950.1"
                     /translation="MKKQKSPILLEMLGLFLGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(59860..60417)
                     /locus_tag="KRQ43_000579"
     CDS             complement(59860..60417)
                     /locus_tag="KRQ43_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2740951.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(60607..61494)
                     /locus_tag="KRQ43_000580"
     CDS             complement(60607..61494)
                     /locus_tag="KRQ43_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH2740952.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            61613..62812
                     /locus_tag="KRQ43_000581"
     CDS             61613..62812
                     /locus_tag="KRQ43_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HBH2740953.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(63006..65561)
                     /locus_tag="KRQ43_000582"
     CDS             complement(63006..65561)
                     /locus_tag="KRQ43_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH2740954.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKKNKKSKEYIVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETAMEGFVNDYLQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKRGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTGEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKS"
     gene            complement(65558..66244)
                     /locus_tag="KRQ43_000583"
     CDS             complement(65558..66244)
                     /locus_tag="KRQ43_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2740955.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            complement(66321..67229)
                     /locus_tag="KRQ43_000584"
     CDS             complement(66321..67229)
                     /locus_tag="KRQ43_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2740956.1"
                     /translation="MFILAFIICTVVIFIVSTKINQRRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKSEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(67231..67902)
                     /locus_tag="KRQ43_000585"
     CDS             complement(67231..67902)
                     /locus_tag="KRQ43_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740957.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKACLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            68164..69228
                     /locus_tag="KRQ43_000586"
     CDS             68164..69228
                     /locus_tag="KRQ43_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HBH2740958.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            69386..70072
                     /locus_tag="KRQ43_000587"
     CDS             69386..70072
                     /locus_tag="KRQ43_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2740959.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINLFKQKVKAFLNHLTTKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            70062..71093
                     /locus_tag="KRQ43_000588"
     CDS             70062..71093
                     /locus_tag="KRQ43_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2740960.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFNISIYLITDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDLSHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIRVATECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            71175..71840
                     /locus_tag="KRQ43_000589"
     CDS             71175..71840
                     /locus_tag="KRQ43_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2740961.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGSLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            71853..74270
                     /locus_tag="KRQ43_000590"
     CDS             71853..74270
                     /locus_tag="KRQ43_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2740962.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNLSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKTISLQGNILSIIFIPLGAI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKQAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     SYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLIRNIEKKSL
                     TERLRSQ"
     gene            complement(74451..75242)
                     /locus_tag="KRQ43_000591"
     CDS             complement(74451..75242)
                     /locus_tag="KRQ43_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH2740963.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(75275..75862)
                     /locus_tag="KRQ43_000592"
     CDS             complement(75275..75862)
                     /locus_tag="KRQ43_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2740964.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(76039..77430)
                     /locus_tag="KRQ43_000593"
     CDS             complement(76039..77430)
                     /locus_tag="KRQ43_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HBH2740965.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(77620..78918)
                     /locus_tag="KRQ43_000594"
     CDS             complement(77620..78918)
                     /locus_tag="KRQ43_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HBH2740966.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSTERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKLLSSDLNN"
     gene            complement(79279..80154)
                     /locus_tag="KRQ43_000595"
     CDS             complement(79279..80154)
                     /locus_tag="KRQ43_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBH2740967.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIKEYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(80347..81033)
                     /locus_tag="KRQ43_000596"
     CDS             complement(80347..81033)
                     /locus_tag="KRQ43_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBH2740968.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(81082..81615)
                     /locus_tag="KRQ43_000597"
     CDS             complement(81082..81615)
                     /locus_tag="KRQ43_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH2740969.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDA"
     gene            complement(81659..82291)
                     /locus_tag="KRQ43_000598"
     CDS             complement(81659..82291)
                     /locus_tag="KRQ43_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBH2740970.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYNTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(82381..83460)
                     /locus_tag="KRQ43_000599"
     CDS             complement(82381..83460)
                     /locus_tag="KRQ43_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBH2740971.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(83593..84939)
                     /gene="pepV"
                     /locus_tag="KRQ43_000600"
     CDS             complement(83593..84939)
                     /gene="pepV"
                     /locus_tag="KRQ43_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBH2740972.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(85008..86288)
                     /locus_tag="KRQ43_000601"
     CDS             complement(85008..86288)
                     /locus_tag="KRQ43_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HBH2740973.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(86415..86675)
                     /gene="hfq"
                     /locus_tag="KRQ43_000602"
     CDS             complement(86415..86675)
                     /gene="hfq"
                     /locus_tag="KRQ43_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBH2740974.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(86789..87724)
                     /gene="miaA"
                     /locus_tag="KRQ43_000603"
     CDS             complement(86789..87724)
                     /gene="miaA"
                     /locus_tag="KRQ43_000603"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBH2740975.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDIDAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKGKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTARWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(87762..89729)
                     /gene="mutL"
                     /locus_tag="KRQ43_000604"
     CDS             complement(87762..89729)
                     /gene="mutL"
                     /locus_tag="KRQ43_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBH2740976.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKDKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(89740..92583)
                     /gene="mutS"
                     /locus_tag="KRQ43_000605"
     CDS             complement(89740..92583)
                     /gene="mutS"
                     /locus_tag="KRQ43_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBH2740977.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(92746..93480)
                     /locus_tag="KRQ43_000606"
     CDS             complement(92746..93480)
                     /locus_tag="KRQ43_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2740978.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(93449..94462)
                     /locus_tag="KRQ43_000607"
     CDS             complement(93449..94462)
                     /locus_tag="KRQ43_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2740979.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(94484..95254)
                     /locus_tag="KRQ43_000608"
     CDS             complement(94484..95254)
                     /locus_tag="KRQ43_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2740980.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(95229..95519)
                     /locus_tag="KRQ43_000609"
     CDS             complement(95229..95519)
                     /locus_tag="KRQ43_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HBH2740981.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(95650..95749)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      96369..96458
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            96511..96687
                     /locus_tag="KRQ43_000610"
     CDS             96511..96687
                     /locus_tag="KRQ43_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2740982.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(96802..97158)
                     /locus_tag="KRQ43_000611"
     CDS             complement(96802..97158)
                     /locus_tag="KRQ43_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2740983.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKDVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
BASE COUNT        35026 a        13977 c        12998 g        35299 t
ORIGIN      
        1 tagatataag ttcatcagca gatatttctg taataaaatt agcaaataaa acagaagcat
       61 gtgtagaaga gcaaatagat tttgtaatag tagtatcaaa tgcaggacca gaaaatgctc
      121 aaaatgttac tttaatagac aatgtttcag ataagcttaa gaaagcagta ttttcacttg
      181 atagaggtgt aagtttccaa ccatggactg gaagtcttaa tataggtaca ctaccagctg
      241 gaactttaag agttattcta ttaagaggaa ttataaaatc aacatgtctt gatagattaa
      301 caaatattgc agaagttact tcaacaacac cagattcaaa ccttaacaat aatatatcaa
      361 gagtgcaagt agaaataaaa caatgttgtt gtaatgattg ctgttgtaac aactgtagta
      421 attgttgttg caatgattgt ggttgtaaag attgttgctg taattgttgt aaaaatgact
      481 tttggtgttg attttataaa ataattttgt ataccttaaa ttaaactgaa ataaaaaata
      541 aattcacata tgagtaaaat attttataaa tattaataaa ttttctatct ttgatatgga
      601 ccacattcgt aatactagtt attaaatgaa gtggtccttt ttaattcatt aaaattattt
      661 attctaatta aattttaaat gtattaaata attttaattt tttataaaaa atattcatat
      721 attctttata ttaaagttta gatatctaaa aatactttta gaatttatta tattatgtta
      781 atttttttat atcttataat gattatattt ttctaactat aaaaatagta tttacttata
      841 tttaaaaata aaagaatttt attcctattg tgtaaagtga gaatactatt ttcttatatt
      901 ggtataataa tagtaaatct ataatataga aaagaggtat ttctagtatg catgaaaata
      961 aaaagaatct attagacgga agcttagctc aatataatga tacagcagtt ccaaaaatac
     1021 cagtatttgc tggtaacgat ataacttcag aagtttatta ttttaaacct aatcaagttc
     1081 ttaatgctca tagacaccct aatggtgaac aaatatttgt gttcctaaaa ggagaaggta
     1141 aaatgaaact tggtgagcat gaatgtgatg taaaaaacgg cgatactgta tttgtaccaa
     1201 caggagagtg gcatgaaatt actaatggaa gcaatgaaga aatggtagcc gttcaaatta
     1261 caaaaattaa tgctggagca gaatacagag gatagatata taagtacagt tagtacttta
     1321 atatctattt tattatataa actttaatct caaatataaa aagagtcttt taaaaggctc
     1381 tttttatatt tttgttaatt ttcattataa aaacaagaaa atatctagct aaaactaata
     1441 tattttattt aatatttttt atagcattgt ttgcaaactc agtatttacg atatctttat
     1501 aaggtgcttc cttatctagt tctttagctt ctttcataac agtcatcaat ttcttcaaac
     1561 cttcctcctt taatacagga ttttgagacc atgcatctat tgatttatat ctatctacaa
     1621 ctgttgttaa atcttctaaa gatatatctt caaagaaagg ttgcatagcc ttagctactt
     1681 ctttgctaga tgcttgttga acccataatt gacctttata aacagcattt gtaaatcttt
     1741 gaattaaatc tttattgttt ttcatgtatg atctcgtagt agagtatgct gtaaaaggta
     1801 tttctccaga atcttttcct atagatgtaa ctatatatcc actaccttct ttttccattg
     1861 ctgttgctgt aggttcaaat gctgttgtaa agtcaccctc tccacctgca aaagctccag
     1921 ccattacacc aaattgtaca tcagttctta cattaacatt gcctgctttt agattttctc
     1981 caatagtaag acctttttct tttagaacat attcaaaagt cattagtgga actccacctt
     2041 ttctaccacc taatatttct gttcctttta aatcattgta agagaaatta ggcatttttt
     2101 tcctagcaac tagaaaacta ccatctcttt ttgtcaattg agcaaagttc actgcataat
     2161 cgtttttgtt ttgattatat acatatatag atgcttcagg acccattaaa cctacgtttg
     2221 cttcacctga aatcaaagct gccatagttt tatctgcacc ttgggtattt ataaggtcaa
     2281 tctttatacc ttcatcttca aagaatcctt tcgtaatagc agcatactgt ggagcataaa
     2341 aaacagagtg agtaacttct gctatagtta ctttatccag atttttagac gaagaagatt
     2401 catctttttt gtcattagag ttaaaatcac atccagttag acatattgta cttacaatga
     2461 tagagcttgc tattgcgact atttttttaa acataataaa tacctcccat aagacatacg
     2521 aatagtatat agtattaaaa atttattgta gttgttacaa aaatgtatct atgcttataa
     2581 tatttctaca aaaacttaat aataattttc agttttatgt ttagtttttt tagtaatatg
     2641 taatattgga taaattatat tgattattta taaactaagt aataaaatta aaataatatc
     2701 acttttttgt ctattatata taaggaaaaa ttttttaata atataaatca tattcattta
     2761 tattattaaa aaatttgttt atagaaactt ttattatttt atataaaaat gataaaaact
     2821 tatattttgt atttaataga gtgttgctaa gtgaatatat ttaaaatgga ggaaacttta
     2881 tgaaacaaaa taaatatgat gatgatagat tttttaataa atacagtaaa atggaacgtt
     2941 ctacaaatgg attagcaggt gctggagaat ggcatgtttt aaaaaaaatg ttacctgatt
     3001 tcaaaggaaa aagagtttta gatttaggat gtggatttgg atggcattgt caatatgcag
     3061 ttgagaatgg agcaatttct gctgttggag ttgatatttc agaaaaaatg ttaaaagaag
     3121 ctagaaacaa aacgcaactt gataatataa attacatatg tatgcctatt gaagatatta
     3181 attttccaaa agatagtttt gatgtagtta ttagttcctt ggcatttcat tatattcaat
     3241 catttgaaga tatatgtaag aatataagta attgtctttc aaataaaggt aattttgtat
     3301 tttctgttga acatcctata tttactgcat atggaagtca agagtggtac tgtgataaag
     3361 atggcaataa tctacactgg ccagtagata gatattttga agaaggagta cgtaagtcaa
     3421 attttctagg agaagaggtt ataaaatatc ataaaacatt aacaacttat ttaaatacgt
     3481 taatgaaaac aggatttgaa atattagaaa ttattgaacc tcaaccagaa gaaaaactgt
     3541 tagatacaat tcctgatatg aaagatgagc tacgtagacc tatgatgtta cttgtatctg
     3601 caaaaaaaag ataagtaaat ataaataatc attattgtag aaaaaaattg tagaaaataa
     3661 ttacactaat ggagatgatt ataccagtgg tattaattac accagtagta aggaggcaaa
     3721 agcattcgtt gcttttgcca ttttttaagt tgcaattata cttctacgta gtatatttcg
     3781 tttccatttt cttctataag ctttttcata tcttcaaatt ttaaaaatac agtagcagta
     3841 ttatcatttg gatgtatacc tattttatcc atttttaata aatccttatc aaatacaact
     3901 tttacaacag cctctttatc atttaatata ccaaaaggag tcacagctcc tttagtaagt
     3961 ttcaagtatt tttgaagtct ttcttctgat gcaaaactaa gaggtttact atcaatttgt
     4021 tgacgaatat cttttaaatc tgcttttttg tctttaccta atacaactaa aaaatgttct
     4081 tttcctttag catcacgaag aaataggttt tttacaacaa attccatatg taatgttttt
     4141 aattcttcca tttcttcaat tgtataaact ggtggatgat ttacagcctc ataaggtatg
     4201 cttaactcat ctaatttttt atatacttcc tgttgttgat tgttcatgat ttcctcccat
     4261 tagaaattta ttttatatat aaataatatt atcacagaaa actttaaaag aaaacgtttt
     4321 atataatata gacaatagat tatattttta taaagaagca agaatactca ataaaactta
     4381 aagaaattaa acaatttcta aaaatacctt gaaaatagaa ccttatttgc catttataaa
     4441 ttatataaaa agggattata taaagtcata tatgaaaaaa ctatattata ctatcttttc
     4501 tttttggaat aaactatact ttaaatatag atatttaatt taaataaatt ttacagtatt
     4561 aatagtaaat tatcttagaa aggaatgtgc tttatatgtc tacagacaaa gttgttggaa
     4621 tcatagatga agaaacggca gaacttgcag gaattgaata tactggtaaa atttatgctt
     4681 cttctggtgt tataaaacat ataaagaaaa aacatagatg tcaactgagt aaggatattt
     4741 ttaatgatat aatagacact ataaaagtgg tattaaagtc acctgaatat ataggaagtc
     4801 atcctaaaaa acctggaaaa agtgtggagt ttataaaaaa aattgataat tatattttag
     4861 tagctacaga attagataca aaaaaaggat atttatatgt atcttcaatg tatgctataa
     4921 aagaagcaaa attagaaagt agagtaaaca atggaagagt aaaacaatat gatggttaac
     4981 ataatattat taattttccc caaaatattg aaaaatatta ttatataagt tataatatta
     5041 atatacacgt agatatttat tagttagatt tgaggttgga aaaggcaccc aatacgctac
     5101 tatagagtag ttaatagaga tgcaggatac gccgccctgc caaatctaat taaattaaaa
     5161 agagaggatt aattcctctc tttttgtttt tttgagatac taatttaatc tatatagaaa
     5221 gattgaaggt catttatact aaaagttttc agttatatac attaaactaa ttaaataaga
     5281 tatttataat ctatatatga tacatattat atattaataa aagaaaaata tatagaaaat
     5341 ccttataaaa atttaaattg taatgaatag taagtaatta aaaagaattt ttattgattt
     5401 ttaaaaattt agttagaaac tatatcatta tggtaaagaa tgtattataa tgtttagaaa
     5461 tattataata aggagcgatt aaacatgaat ctatcgaaga aaatagaaga taaaagaaaa
     5521 gctaaacaga gagctgaaaa agttaagaaa gctaaaattg ctacagctgg tgtggtatta
     5581 ggagctgtta ctggtgcagt gagtggagta cttttggctc ctaaatctgg aaaagaaaca
     5641 agagaggata taaaagatgc ttcacaacaa attgctgaaa agataaatat gaaaactgta
     5701 gatgtaaaag gcaaagtatc tgagaagcta gaggataaaa aaggaaactt tatagaatca
     5761 aagaaaaaaa taaaaaaata tatagataac aaaaagagtg ttgaaaattc tagtgaggaa
     5821 gataaaataa tagatatagt tgaaccagtt agtgttactg aggaataata tggacaatac
     5881 aataacgatt aacataagta taatatatgt attattagct atacttgctt gtattgcttt
     5941 agtttattta attattgtac ttgttaaact acataagatt ttaaataatg ttggaactat
     6001 gttaaatgaa aatactcaaa atataaatac aactttaaat aatcttccta atgttgtaga
     6061 aacttttgga gaagtaggag aaaatatgaa agatgtaaca gaagtagtta ctgaagttac
     6121 agcagatttt cttgttacta aagacagtgt caaatcaaat atggatgtta tagtcgatat
     6181 attgactata attaaaaata tttttctaga taaaaagtaa taaatttaat ataaaataag
     6241 atataattta aacgacctta aaataacatt tataaggtcg ttttttatta gcttgatttg
     6301 acactatgtg tttttaataa ttggtaatat tcctctttat catttgaaca tatatatcta
     6361 tgcttgttgt ttcaattaca tccataagaa catctttaca ttcaagctca aaatcttcca
     6421 ttccttctaa atattcatca tcttcatcaa aaaagatata agaattatat agccattctt
     6481 caaatttttc ttcaagtata tcccaatacg aactccaaaa taatccacaa cctgatatat
     6541 aagatgctct actttgattt atataaacct catttagaag cttttgtaat ctactgctat
     6601 aaagaaaatc tgctcttcca ctgcttgata ttaattcatt taaatcttct attgacatta
     6661 attcaacttt accactttta tcataaggag tataattttc atcaacccat ttatgtggtt
     6721 tgttttctct gcatactgtt gctatcaact ctacaacttt tgttcttatc atttttttat
     6781 cctaacttat ttatttttta taaaataatc atgattttat aatttatcta tttcttgtaa
     6841 tgctaattta acagtttcat atctatcagc accatttatt actacatcac cttttacaag
     6901 tttattagct tctccaccta caacataaac ctttttacct aaaccttgct tataactaga
     6961 cgcctcaatt attaaagaat ctttcaattg ccaatgtaaa atctgagcag ccactttatc
     7021 agcatcacct gtataaacga ttacattttc atacacttta ttttcccctc ccccttgaga
     7081 atttgatata gatttgttta gtataccttc tgctatcaat ttagcaactt tatctttatt
     7141 attaacataa taatctgtat ctgctttact atctacaaaa catacttcta ttaatattgc
     7201 tggtgcaata gtatgattaa gccaataaag acctctaaca tcagactttg cacccctatc
     7261 tttgaatact gtagctaacc tagtattcac tctttctgca taggttttgc cattattagt
     7321 cttatatatt gtttctgtcc ctactggagt tgaagttgta gcatttgaat taaaatgaat
     7381 ctgaacagcc aaatcagttt cctgtttatt tgctatagca cattggtctg ctaaatgatt
     7441 acttgattca tcaactcttc ctgtataaac agtagctcca cctattttaa gccatttaac
     7501 aattaagtca ttcagtattc ttgtttcttt gctttcgttt atatacccaa cagctcctgt
     7561 accttttcca attaaagtgt gccctggtat tattactact ttcaaactaa catctccttt
     7621 acaattaaat ttaacttcta tttaatatat gcataaccta gaattttgtt tctttttata
     7681 tcttatactt ttattataac ccattttgta aaaatataga atattaagta aataatgtta
     7741 aaattataat tttgtatata agacattact tgattgcaat aattttatag catattcatc
     7801 tattctatat ccagttctat aatatatatg tttaattcca gcttgaatta tagccttagt
     7861 acaatttaag caaggaaagt gagttacata aatagagcaa tctttaactg aaataccttc
     7921 ttttgcacaa taataaaggg cattttgttc agcgtgaatg gttctaatac aatgtccatc
     7981 tctcatttca tgaccaactt cactacaatg cttatctcca gaaatactac cattatatcc
     8041 agtagacact attctgtttt ctgaattgac aattatagct cctacataag ctctatcaca
     8101 agttcctctt tcagctactg tttcgcacag tctcataaaa tattcttgcc atgagcatct
     8161 attttcaagt tttttattca aatcatatac ctccaaaatt tatatctaat atataagatt
     8221 tataccttaa aaataatatt aaaaacaaat ttatacgata aataaaattt attaatactg
     8281 tttttagtct aaattatttc attttaaatt aaagttacaa ggaatctaaa attatatata
     8341 tctttcttcg taatatgaat gttacaatat aaaaaactgt ctcaataaaa tagagacagt
     8401 tttacagtca aagtttataa tacaagttca tatttttctt taaattcttt tacagcttcg
     8461 ggccatgcct tttgttctgt aatacctttt tctttagcta ttttaattgc aatctctctt
     8521 atcattgcag cgccttctaa tattcccatt tttaatctcc cttcaaatat ctttttgtat
     8581 agaatataaa tagtgctaag atttattaca tgctgcatat acaatatcta tacaacacat
     8641 aacttgtaaa ttccttttat tttcatacgt ctttaaccga catataatta tattcaataa
     8701 gttttaaaat tatgaactca attataatta tttttatttt tttagaatct aaacactaaa
     8761 aattgtaggt aaatttgtct tatgccttta taaatatttc tacagtttta attactggac
     8821 atatctattt ttattataaa aagcgcttaa aaatcgagaa tatccgcgta aaagctgtat
     8881 ataagcaaaa cgattaaagg aaaaagaaga aatttacttg aatgttaaaa tgcgttgctt
     8941 gaagcaacgg gcagttttgc ctataatatc ggtaacaact gaaagaaagg tggttagccc
     9001 taatgttaag cgaaaacatt aaaacaatca ggaagtcaaa aggactttca caacaagaac
     9061 ttgctatcaa actgaatgta gtgcgacaaa caatatctaa atgggaacaa ggactgtcgg
     9121 ttcccgattc tgatatgttg atttccatat cagaggtgct tgaaacgcct gtaagcactt
     9181 tacttggaga aactattgtt gagtcggaag ttgatagctt aaaagtgatt tctgaaaaat
     9241 tagagattat aaacttgcaa cttgcacaaa gaaaaaacat gagaagaaaa atgtttcatt
     9301 ggttatttat tttattatgt gcagtcatag taatagtttt tgtggtctta gggggactaa
     9361 atagtcctta cttggattgg aattataccg accctgaaac cgctgttttt ggagtagctt
     9421 ttcatgcttt tgagtggcta tttgtcagat tagtaccgat tgtccttata ggagcaatta
     9481 ttggaatctt tttgacacgt aagaaaatat gaagtaactc tgctttttat aatatagcaa
     9541 gcgttcctta aaagtgtcat tctacatggc aatcgaggac aactatgtaa ggaagaacct
     9601 ttttgatttc caactaagcg aagttattga ggacgccagt aggcccaaaa ccgcattaag
     9661 taaagtacag gaagcaagac tgctggactt atactctcat gcgtcagatg cagaaaatgc
     9721 gaggtctgta gcatgattta caacgatttg tacaacgact acgagtagaa atatatggag
     9781 ataagtatta tctacgaaat cagaaaagaa atgacttgat aatttactca tgttataatt
     9841 attgatgtga aattaataaa tcgaaattcc ttttttagat ttaacaatac tgagtaagga
     9901 aaaagtgaat gacttttgca aggaggtgtt aatatcaggc aaataaagtc ttttgttttt
     9961 ccagttatat ccttaatatt cttagatcaa attagcaaag ttcttatagg attattctta
    10021 atggactttg aaattgatat aattgggaaa tttttaagat tcaatcctgt tcaaaataca
    10081 aaattaagtc tctgctatct aacaaacgga gcacaaaaat gaaaattaaa tattaaatat
    10141 aaagcacagt taattttgat taaaaagttg actgtctttt cttttttata aatttaagca
    10201 tgggtaataa agaaatgact gcatttaagc attatgtata taattggagg caataaaaag
    10261 ccagcaaagc ccataaaata gagctgtgct agcaacatga tgagttataa gaagataatc
    10321 aaaagcttac gctttatttt aatttaaaaa aatgattact gtaaagaaat cattttttat
    10381 tataatcact gatacatcaa atattctaaa taaaattttt atttatctgg aattgtatat
    10441 tttttctata atattaacta cagcgtacat tgcccaagca caaatagcca atacaaatac
    10501 tcccatcatt actaaatcta atttaaatac ttgagaacca tatactatca agtagcctat
    10561 tccatatctt gaaactaaaa attctccaac tattacacct acccatgcca taccaatatt
    10621 aattttagtt aaatttatta aatttcctgt gtttgcaggt aatatgagtt taaataatat
    10681 ttgagattta gtagctccaa agctttttaa catcttaatt ttttcttcat ctatattcat
    10741 aaaataatta taagctgaaa gtatagtaac aacaacagaa atcgttacag ctgttacgac
    10801 gattccttct attccagcac ctacccaaac tataattata ggagctaaag cagtcttagg
    10861 aagagcattt aaaactacca aaaatgggtc taatattttt gataattttt ctgaccacca
    10921 aagagcaatt gctaccaaaa tacctaatac agtacctata acaagaccaa gaacagtttc
    10981 atatacagat attccaatat gtttaaataa ttgaccacta aatgcatatt gaataaataa
    11041 attgtaaata tcacttggtt tgctaaatag aaatgtattt ataacattta agtcagctaa
    11101 aagttcccag attacaataa aaccaattaa aattaatagc tggtagaata atacatttct
    11161 tttttctctt tttacacctt taacatagtt tatatatcct tcagatcttt tattaagcct
    11221 catgtgtatc tagctccttc cataatatgt cgaaatactt ttgaaaatca ggaactttac
    11281 gtgttttgag aggcgttttt gttccatcca tgttaagttc aatatcgtaa atatttttta
    11341 tggtagctgg tcttttagat agtattgcaa ccttatctga tatgcttatt gcttctgcta
    11401 tagctaaaaa agtgcaacta attgcttaaa gaaacagaat tatccacttc agcacccata
    11461 taaacaatat taagatttcc taaactgcta tcccaaatga tactattaat aatagtagat
    11521 aataacaatc tcttatcatc taaactggca ttatcaactt catcattaaa tctcttcaaa
    11581 ttactaacaa taatatcaat attaatactg tcactactaa tattgatatt actagattcc
    11641 aaaatattaa tcttatcctt taaaatacta atctcattat ttaggctctc aatctgggaa
    11701 actatataat cagaagcagt actaccagta ttttttgcaa gctctataac taaattttta
    11761 ataagtcttt ccttatctaa aatttgattt ttaagtaaat tagtctcaga tttaaaaata
    11821 ttaaaaacat tatcagtctt aatgttatta ctattgaatg cacttataat agactcttct
    11881 ttacaattct taattttatc tataactaaa ctttcaacta atggaccatt aagattttta
    11941 cagttgcaac tatcagaccc aagtgttttt ttagtaccac aaatataata atactttaaa
    12001 tccttgtcag tttttttgcc tttataggta attctcatat tagaaccaca tttaccacat
    12061 tttataagac cagataaaag agcagttttt ccagttgata tccttggagt tttatcacga
    12121 tttttatcta attgattttg tacttcaagc catatttcag gttctatgac tccatggtgt
    12181 tttgcaattg ctgctattga gttagatgta tttttagcat aggtaaggat tccacatttt
    12241 ctatctggag tacctacaac atccatacca ctatttttaa ggtaatctaa aatttcatca
    12301 ttagctttta catatgctgg atttctaagt attctagata aagaactagg gtcaaattta
    12361 ccaccacgag gaccccttat tccattatta tagacatatt tatataactt agataaggac
    12421 ctaagttcta aatatttatt gtatattagc tttacaatct ccatttgttc atcatttact
    12481 tgaagcttat acatacttct ttcttttaga ttttcatcta agaatgtgat tttttcactg
    12541 ttgaatccat gaggtgtatt gcctccaagc catctaccac tacgggctaa ttcatacatg
    12601 ttgtctttta tacgttctgc tattgtttct ctttctaatt gagcaaatac acttgatata
    12661 aacatcatag ctcttcccat tggagttgaa gtatcaaatt gttctttgat agatataaat
    12721 gatatgttta gttcatttaa tttttctatt aaagtagaga agtcagatac atttctcgat
    12781 atcctatcta atctataaca aactaggtaa ctaaatttct tatctttagc atcctgcatc
    12841 attttcttaa attgtggtct atctatattg ctaccactaa atccctcatc ttcatatatc
    12901 aaaaaatctt ttacaccaat agactttgca taatcaatac ataattgtat ttgattttct
    12961 atagaatcac cttttccagt aaatcttgat tttcttgaat aaattgcagc tttcaaaatt
    13021 aaaacctcct ataaattagg atatatattt gaaattattt atatacaacc ttttaagtaa
    13081 acttattaga ataaatttat taattaggta aatttatata attctacttt ttataatata
    13141 tgactattta ttttatttct ttactattca agttctaaat caataataaa ttttgatatt
    13201 taattgtatc aggacaaatc tctaatttca tatattatta atataaaatc ataggttagt
    13261 gtgaaaaagt tgaaatttaa atattttaaa agataatttt ttggaactaa taggtataac
    13321 aaaaatttat agggggattg catatggaaa tcaatgttat agaaattttc cctaaagata
    13381 aagctaaact taataaaata gaaatggata aagctagttg gtttgtaaat ataataagta
    13441 aaaaatatcc taaagaagct ttaaatgaag catttagtat tttagaaaaa gaattaaata
    13501 taagtaaagc taatacataa gctttgatta ttgattttat atactattgg ttttatacgc
    13561 tatgacttga cattatatta atcaaatagt atatttttaa atatagcaca atgaagtgtt
    13621 aaaagagcaa tggagctcca tagataaagt ctatggagct tttttgcgta tttaacttaa
    13681 ggaggataga gctttgaata actttgagat taaaactaga ataaaatttg gagaaggttc
    13741 actaaaagtt ttgcaagaat taaaaaacaa aaatgtatta ataataacag acccttttat
    13801 ggtgaaatca aaaacaatag ataaaataac atctaattta ataaactcaa catatcaagt
    13861 ttttgaagaa atagtaccag acccaccaat agaagtagta gtagcaggaa tagaagcatt
    13921 taaatctata aatccagacg taataatagc attaggtggt ggttctgcaa tagatgcagc
    13981 aaaatctata atggactttt ctaaaaaaat attaaaaatt aacgaagtag agtttatagc
    14041 aataccaaca acaagtggaa caggttcaga agtaacatca tttgctgtaa taacagatag
    14101 tcaaaaaaaa tgtaagtatc cattagtgag tgatgattta cttccagata tggcaatact
    14161 agacccagag cttgtaaaaa ctgtaccaaa ttttataaca gcagatacag ggatggatgt
    14221 attgacacat gctatagaag cttacgtatc tacaaattct aatgactttt cagatgcact
    14281 agctgaaaaa tctataaagt tagtatttaa atacttaata aaagcatata aagatggaaa
    14341 tgacatagaa gctcgagaaa aaatgcacaa tgcatcttgt ttagcaggta tggcatttaa
    14401 ccaagcatca cttggcataa atcattctat tgcacatgta ttaggtggaa aattccatat
    14461 accacatgga agaacaaatt ctatattact tcctcatgta atagaatata attcatcaat
    14521 agtaggatat actaacacaa cttactctga tacagctaaa aaatatgcac aaatagcaga
    14581 attagtagga cttgggagtg ctaatataag aatatctgtt agaaatttag taaatgaaat
    14641 aaagaaacta caaaaagaaa tgaatatgcc aactaaattg acacaatgca aattaagttt
    14701 agaagatata actaatgaag aaagagaaat agcaaaactt gctataaaag atacttgtac
    14761 attaactaat cctaaggtac caactgaaga tgatataata aacatattaa ataacattaa
    14821 ataactacat tttattacat gtaaatataa tattatacaa atagggaaaa tgtttttaaa
    14881 aatataaatt atatattgac aaatataaaa cataaaacta taatgaaagt atcacaaagg
    14941 cgtgatactt tagtagaaag caatggagct tcttaggaat attaatatta ttcttatgga
    15001 gctcctttta ttttaagcaa atagcttttt aataaactat attcaaagaa agcagggaat
    15061 aaatttgact gaagaatcta agcaaagagt tattcaagaa tatgttcctg gaaaacaggt
    15121 tacattagca catatcatag ctaaccctaa tgaagacata tataagaagt taggattagt
    15181 acttgataaa agagatgcaa taggaatact tacaataaca ccaagtgaag cgtcaataat
    15241 agcagcagat gttgctacaa aggcttcaaa tgtatcttta ggttttatag atagatttag
    15301 tggttcagta gtaatatcag gtgatgtaag ttctgtagaa tcagcgttaa atgatgtttt
    15361 agaagtctta ggaaatatgt taaacttctc atctacaaaa atcacaagga cataataata
    15421 caatgaagaa tataatattt atgggaaaga caggtagtgg taaaactacc ttatgtcaaa
    15481 aactagacca gttagaatta aagtataaaa aaactcaatc agtggaactt tataataatg
    15541 caatagatac tcctggtgag tatatggaaa atagaaacct atataatgcc ttaataacaa
    15601 catcagcaga tgctaaaatt atagcaatag tgtatgatgc cacacaagaa gaaaattata
    15661 tagcaccagg ttttgccagt atgttttgca aagacgtaat aggaattata actaaaataa
    15721 ataaagctac tgaaaacgaa gtcaatatag cttatgaaag actatcacta gcaggagcaa
    15781 gtcaaatctt taaaatagac acagttgatg atattggact tgaaaaatta tttaaatatc
    15841 tagaaaaatc taaaaatata gatgaagttt aaggggaaat atttttttat tcaaaaatat
    15901 tattaaagta tgataaaata aaaaaatgta taaactattt taagaagatt taatctttaa
    15961 gcgaggtagg aacatgggga aaaaaatact attggttgat gatgaaccac tgttaaggat
    16021 ggatacaaaa gatatattag aaagtcatgg ctatgaaata ataggcgaag caagtgatgg
    16081 atttgaagct gttgaaatgt gtaaaaaaca caaacctgat ttagttataa tggatataga
    16141 gatgccaata cttgatggta taaaggcagg caaaataata tgtaaagaaa atctagctgg
    16201 tggagtactt ttattaactt catttgaaga taaagaatac gtagaaaagg ctaaaagtat
    16261 aggtgcttat ggatatttag taaaaacagc aagtgaaaaa tcacttatcc caaccataga
    16321 aatgtgttta aataaggtaa atgaatttga aaaaatgaaa aaagatttag aaaaagtaaa
    16381 ttctaaattg aatgaaagaa aattagtaga aagagcaaaa ggtatactta taagagagtt
    16441 taagatttct gaggatgaag catacactag aataagaaaa ttaagtatgg ataaaagaac
    16501 tacaatgatg gaaattgcca aaatgattat aataggatac gatgactaat acgataaaaa
    16561 aaatatcaac tgcacaaaca tacttaaata ataacgaaat tgaaaaaatt atagaagtat
    16621 caaaatcctt agatttaatg gcttcttttt atgaggctga tgtttttata gatgtactaa
    16681 gtaaatttga tgatgaagca attgttgtgg cacatggtag acctaaagaa aagtcaatgt
    16741 actgtgaaaa tgttataggt aaaaaggctt taattgaaaa tgaaccagga gttataaagt
    16801 gcttaaaaac aggagaaaga gtaagagata ttaaagcttt aacacaggaa tataaactgg
    16861 tcaaacaaaa tattcagcca ataacactag atgacaaagt tttagcagta ctaatagttg
    16921 aaaaagatat aagtagtgaa gttaagaatg agtttaatgc tagtgaagac gaagaaaata
    16981 aaaatttaca tcagtttata aaacttatcg gaaataatga ctttttagtt gataatttaa
    17041 attcagccat attaatattt gataaaaatg gaaaattaaa aattaaaaat cgtattgcaa
    17101 ctgagatata caaaaatctt gggtttggat atgatataca agatatgcat tacaatgatt
    17161 tagatataga aaccaacacc tttgaaaata tattaatgga tgaaaattat gatgagacaa
    17221 atgaagtttc aataggtaat atgtttttta aaataaagac catatacatc aaagatgatg
    17281 aatttaaggt ttgcaaaata gtacaagata taagtgattt aaagagaaaa gaagaagaat
    17341 tagttttaaa aacagtggct ataagagaag ctcatcatag agtaaaaaat aatcttcata
    17401 cagtaatatc tataataaaa aaacaaagta gattatctca aaatgatgaa gtaaagcagt
    17461 gtttagataa cataataaac agagtatttg caatactttc aactcattat ttactatcta
    17521 aagaagttga taataatata tctatacgag aaggtatcaa tttattagtg tcaaatattc
    17581 aaggtggcta tttatttagt aaggatatag atatacgtat aactggtgaa gattttaaaa
    17641 ttagtggaga aaaagcaaca gcaatacttt tggttataaa tgaaatacta caaaattgtt
    17701 atgaccatgc attttcggat agagaacatg gtactataca aatattaata aataaagata
    17761 acgactatag aaatattgct attatagatg atggaattgg atttgatagt aataatataa
    17821 ataaaaatag cttagggaca tatataatag atagttatat aacacagatg ttaaaaggaa
    17881 atatagagag aaaaagtaat gagaatggta cagaagtatt aattactata cctacacaaa
    17941 ttaatattta aataataact catctacaaa gtagtagttt taattgagca aagaggctta
    18001 aggttattaa tagattaagt taattgaatg tatttataaa aattataagt atatattcaa
    18061 tttaacaggt atttattata actttaagcc tctttgcttg tttaagacat acttaaattt
    18121 taggaggtga gaaaatgaga gaagagttat taagtgttgg tattgacatt ggaacaagta
    18181 ctactcagtt aattttttct aaattaatag tagaaaatac tgaatcaaat ttttcggtac
    18241 ctagaataag tatagtagac aaagaaatta tttataaaag caaagtttat ttcacccctc
    18301 ttatttcaaa taatgaaata aatggtcaac aaataaaaga tatagttgaa aatgaatata
    18361 aaaaagcaaa tatatctaaa gaggatatac atacaggagc agtaataata actggtgaaa
    18421 cagctagaaa agaaaatgca aatgatgtac ttcatacttt gagtggattt gctggggact
    18481 tcgttgttgc aacagcagga cctgatttag aaagtataat atcaggaaaa ggagctggag
    18541 ctcatattta ttcaaaagaa cattcaacta caattgtaaa tatagacata ggtgggggaa
    18601 ctagtaacat agcctcattt aaaaggggag aagtaaccga tactgggtgt ttggatatag
    18661 gtggaagact tgtgaagata gataaaataa gtaaaaaaat aacttatata tcacctaaaa
    18721 tagataaaat cataaaagat aataatttaa atcttcaagt aggcacaatg gctactgtag
    18781 aaaatacaaa gccaatagtg gatataatgg ttgacttatt aatggaaagc ataggattaa
    18841 agaaacagac acctttgttt gattttataa taaccaataa atcaataagt atagatgaaa
    18901 atattaaaaa tgtttcattc tctggtggag tagctgatta tatttactat gatggagaaa
    18961 taaaagatta ttttgaatat ggtgacttgg gaattttact tgggcaaaca ataaaaaatt
    19021 gtgaatacct taaaaaagta aatgtagtta aatctatgga aacaataaga gccacagtgg
    19081 ttggggcagg ttctcatact actgaagtaa gtggaagtac aataacttac actagcgaaa
    19141 agtttccact taagaacttg ccagttttaa aattatcagt tgatgaagaa acaggtactt
    19201 caaaacaaat cagtgaagct ataaaaaata aacttaattg gtttaaacta gaaaatgatt
    19261 tgcagaaagt tgctatagcc atgataggaa agaaaaatcc aaccttttta gatatacaag
    19321 agtatgctaa agggtttgta gatggaatgc aacaaatcat agaaaatgat ttacctttta
    19381 tagtaattgt tgaaaatgat atggcaaaag tgttaggtca agcaatatat gcattattaa
    19441 attatgaaaa agaaattgtt tgtatagaca gtgtcaaggt tgaaaatgga gactatatcg
    19501 acattggaaa acctatagtt gaaggtaaag ttttacctgt ggtaataaaa acattagttt
    19561 ttaattaata gaaggaggta agtaaatgat tttaaataca aaattatttg gacgtactta
    19621 tcagtttaaa ggcttatatg atgtaatggc taaagctaat gaagaaaaat caggagataa
    19681 attagcaggt cttgcagcag aatcagctga agaaagaata gcagcaaaag ttgttttatc
    19741 acacataaaa ttggaggata taagaaataa tcctgcagtg gcatatgaag aagatgaagt
    19801 aacaagaata atacaagatg ctgtaaatga aaaagtttat gaagaaataa aaaattggac
    19861 agtatctgaa cttagagaat ggctattgga ttcaaatact acaagtcttg atataagaag
    19921 aatatcaaga ggattaactt ctgaaatgat agcagcagtt gcaaaattaa tgtcaaatat
    19981 ggacttagtt tatgcagcta aaaagataaa ggttactgct cactgtaata caactatagg
    20041 agaacaagga acattatcag caagacttca acctaatcat ccaacagacg acccagatgg
    20101 aatacttgca tcacttcttg aaggtttaac ttttggtata ggagatgcag tacttggatt
    20161 aaatccagtt gatgactctg ttgagagcgt tactaaagta ttaaaaagat ttgaagaagt
    20221 aaaacaaaaa tatcagatac caactcaaac atgtgtattg gcacacgtta ctacacaaat
    20281 ggaagcaata agaaatggtg ctcctgcaga tttaatattc caatctatag caggttctga
    20341 aaaaggaaat gaagcatttg gatttaatgg cgacactata gaagaagcta gacagttagc
    20401 tttaaaacac ggtacagcta caggacctaa cgttatgtat tttgaaactg gacaaggttc
    20461 agaattatct tcagaagcac atcatggaat agaccaagtt actatggaag ctagatgcta
    20521 tggatttgct aaaaagtatg aaccattctt agtaaataca gttgttgggt ttataggacc
    20581 tgagtactta tatgatgcta gagaagttgt aagagcagga cttgaagacc actttatggg
    20641 taaactacat ggcttaccaa tgggtgttga tgtttgttac actaaccata tgaaggctga
    20701 ccaaaatgat atggaaaact tagccatact attaacaaca gcaggatgta cgtattttat
    20761 gggaatacct catggagatg atgttatgct taactatcaa acaacaggat accatgaaac
    20821 agcatcactt agagaaatgt ttggactaac agcaataaaa gaatttgatg cttggatgga
    20881 aaagatggga ttctataaag atggtaagtt aacagagttg gcgggagacg catctgtatt
    20941 attaggatag gaggtattta atatgaatga gaaggattta aaagcattgg tagaacaatt
    21001 agttggacaa atggttggag aattagatac taatgttgta tctgagactg ttaaaaagac
    21061 aactgaagtt gtagtagaca acaatgcttt tatagatgat ataacagaag ttgatataag
    21121 aaagcaatta ctagtaaaaa atcctaagga tgcagaagct tatttagata tgaaagcaaa
    21181 aacacctgca agattaggta taggaagagc tggtactaga tataaaacag aaacagtttt
    21241 aagatttaga gcagaccatg ctgctgcaca agatgctgta ttctcttatg tagatgaaga
    21301 atttataaaa gaaaataata tgtttgcagt ggaaacttta tgtaaagata aagatgaata
    21361 cttaacaaga ccagatttgg gaagaaaatt ttctcaagaa actataaata atataaaatc
    21421 taaatttggt acaaatcaaa aggttttaat attagttgga gatgggctta gctcagctgc
    21481 aatagaggca aatttaaaag actgtgtgcc agctataaaa cagggtctaa aaatgtatgg
    21541 tatagattca agtgaaattt tatttgttaa acattgtaga gttggtgcta tggaccactt
    21601 aggtgaagaa ttaggttgtg aagttatatg tatgttggtt ggagaaagac caggattagt
    21661 tactgctgaa tcaatgtcag catatatagc ttataagcca tatataggaa tggcagaagc
    21721 aaaaagaaca gttatatcaa atattcacaa aggtggaaca actgcagttg aagcaggtgc
    21781 tcatatagct gaacttataa aaactatgtt agataaaaaa gcttcaggaa tagaccttaa
    21841 ataaagtcga gggagtgtag aatatgaaaa atgatgtaat tcgtcctaat atactaggaa
    21901 ttaaaataat ttcgaatata agtccagaaa tggcacaaaa actagaatta aaatcacatc
    21961 acaaaagttt aggtttaata actgcagact gtgatgatgt tacgtataca gctcttgacg
    22021 aagcaactaa agcttcagag gttgatgttg tatatgcaaa atcaatgtat gcaggtgctg
    22081 caaatgcttc aacaaaactt gctggtgaag tattaggaat aatagcaggc ccaagcccag
    22141 cagaagtaag aagtggtcta aatgcagtag ttgattttct agagtatgga gcaactttta
    22201 taagtgcaaa tgatgatgat tcaatagcat actatgctca ctgcgtatca agaacaggta
    22261 catacctttc agagatagca ggaataagag aaggtgaagc attagcttat ttagtagcac
    22321 caccacttga agcaatgtat gcactagatg cagcaatgaa agctgcagat gttaagatgt
    22381 gtgaattatt tgcacctcca actgaaacaa actttggtgg agcattactt acaggttctc
    22441 aatcggcttg taaagcagca tgtgatgcat ttgcagaagc agtaaaatca gttgcagaca
    22501 atccaacagg attttaagga tagttagatg gatgctatag gcttaataga agtaatagga
    22561 tatgttgctg caatagaagc ttctgatgct tgtttaaaat ctgcaaatgt taatattgta
    22621 agaattgata aggttggggc aggtattgtt actttaacaa tatgtggaga tgtcggtgct
    22681 gtaaaagctg ctttagaagc aggtgaaata gcagcttcca gagttggtac attaagaaca
    22741 tcacatatta taccgagaat ccataatgaa gtaacaaatg ctttattcaa aactaaagaa
    22801 cctaaagtct gtgaagtttc agaagataaa gaaaaaaact ttgagattac attggaaata
    22861 actgataatg tatcgaaaaa tttatcagaa aaagaaaatg taattttaga tgtcaatgaa
    22921 aacagtggag atactgaaaa tttatatagt gatatagata aaacaaacaa aaaaattgaa
    22981 acagttgatg atagtttaac agaagctaat gaggaaaaaa tagaaaatac taatgataaa
    23041 gaagtattgg aacaagttaa aatagaaaat tccgattttg atagagatga cctatcaaag
    23101 aacagtgtaa aaaaacttaa agctatggct aagaaattag attcttcaat aacttataaa
    23161 gatttaaatg ttcttaaaaa agaagaatta ataaacttag ttaaaaagct tagcagaagg
    23221 gatagatagt tatgacactt ttagataaag atttagtatc tatacaagaa gtcagaactc
    23281 ttgtaagaag atctaaagtg gctcaagaga aactttctaa aatgagtcaa gagcaaatag
    23341 ataaaatagt aaaagctgtt gtagatgcag catttaataa tgctactaaa ttagctaaaa
    23401 tggcaaatga agaaactgga tttggaaaat gggaagataa agtaattaaa aatacttttg
    23461 catctatggg agtttatgaa actttaaaga acacaaaaac tattggaata attggtgaag
    23521 ataaagaagc caatacgata gatatagcta caccagttgg agttgtggca ggtcttatac
    23581 cttcaacaaa cccaacatca acagtaatat acaaaactat aatatctcta aaagcaggaa
    23641 atactatagt tttctctcca catccaaatg caaaaaactg catacttgaa acagttaata
    23701 taataagtga ggctgctata aaggctggag ctccagagga ttcaatatta tgtataacta
    23761 atccaagtat agttggaacc aatgaattga tgaaacataa agatacaaac ttaatactag
    23821 caactggagg agaagcaatg gttagagctg cttactcttc aggaacacca gctattggag
    23881 ttggaccagg aaatggacca gcatttatag ataaatcagc aaatgttaaa ttagcaatca
    23941 aaagaataat agattctaaa acttttgata atggtgttat atgtgcatca gagcaatcta
    24001 tagtaataga aaaatctatg gaagaaactg ttttaaaaga gcttaaaaat caaggtgcat
    24061 atgttttaaa tgaagaggaa agtgaaagat tagcaaaatt catattaaga gctaatggta
    24121 ctatgaatcc acaaatagtt ggtaaaagtg ttgaggtaat agcaaattta gcagacttaa
    24181 caaatatacc taaaaataca aaagttctag ttgcaagaga aaataaagtt ggtcacaatg
    24241 tagcctattc aagagaaaaa cttacaccaa tactagcgtt ttatgttgaa gaaaatgtag
    24301 aagctattat gaacagatgt agagaaatat tgttaaatga aggtgcaggt catacattct
    24361 caatgcatgt aaatgatgaa gaattggtaa aaagatttgc ccttaatatg ccagtatcaa
    24421 gaatacttgt gaatactcct tcagcacttg gaggaatagg tgcatcaaca aaccttgtac
    24481 cagcactaac acttggttgt ggtgcaatag gtggaagttc aacttcaaac aatataggac
    24541 cacttgattt aataaatgtt aaaagagtag cttatggaat caaagaaata gaagaacttg
    24601 gaagagataa atctcaagtt gaaaaatcaa tgtttgactc aatggataaa gaagaattaa
    24661 taaatcttct tgttcaaaaa ctagtcaaag aactagcata actaaaataa acaatgaaac
    24721 ttatggctat cgctataaat ttataaaaat ataaactata aaaaactata aaattaaatt
    24781 tttggaggat aagattatgg caagtgcaaa cgcattagga atgatagaaa ctaaaggatt
    24841 agtaggagca atagaagcag cagatgcaat ggttaaagct gcaaatgtac aattagtagg
    24901 aaaagagcaa gtaggtggag gattagttac tgtaatggta agaggagatg ttggagctgt
    24961 taaagctgct acagatgcag gagctgcagc tgccgagaga gttggagaac taatatcagt
    25021 tcatgttata ccaagaccac actttgaagt agatgctata ttaccaaagg tatcagctga
    25081 gtaatataag aataatttta aaatttaaat tttgattgaa aaagaggcta tctcaaaaat
    25141 gagtcttact aataaactca atgtattttg aggtagtctt ttttatacat ctaataggag
    25201 atgtgataaa atgggtgttt taacagaaaa cgaagtaaaa agaaaaattg gaaaaaacaa
    25261 aaataatata actgaatttt atatagaaaa aggtcaaata ataactcctt ctgcaaaatc
    25321 ttatttagct gagagaagta ttgagcttaa atatgttgat aaactttcag atgtaaacaa
    25381 tgaacctaaa gaagttgtaa aagaagtagt taaagagaaa aaatataaat atactactgt
    25441 atttggcgct aaattggatg aaaaaccaga acatatgact caattaaatg gaaatctttt
    25501 agtttttaaa gaccataaaa gaataatatt gagaggaaaa atagattctc ttgaatcaga
    25561 aatactaaag gtacagatac tttgtcagaa actagatatg ccaaagcttg ttaaggaatt
    25621 gcaagaagta ttagactttg taagaaatat aatgagatgt gaagttttag atgaaaagct
    25681 agaagacttt aaacttttag gattaactcc tcaagaactt agagaacaat ctcactatcc
    25741 taaaaaatac tttggtatag gacatgaatt cccaagttat gaaatgggag aagtagtagt
    25801 agctataaat agtataagaa gtaatacacg agaggttgaa cttgcagcct atgaagcatt
    25861 taagggtgag tatggaaatg ttcacagaga agatttaata aaggcactta atagattatc
    25921 gtcagtattt tggataatga tatataaggt tagaactaat aagtataagt agttggagga
    25981 cataatggag aatctattaa atgaaatagt ggaagaagta ataactagag ttaaaaaaga
    26041 agcatttata gaagttgaag catcaggaag acacgttcac ttaagtagag aagatgtcga
    26101 taaattattt ggagaaggat atactcttac aaaactaaaa gacctatctc aaccaggtca
    26161 atatgcatgt aaggaaagag ttacaataac tggtcctaaa ggaagtataa aaaatgtagt
    26221 tgtacttgga ccatgtagaa atgaaactca ggtagaaata tctttaacag atggttcaac
    26281 tcttggacta aaagctccta taaaacaaag tggagactta gaaggtactt taagtattaa
    26341 aatatcaaca caatatggtg aagttgaact tgataagggg ttaatggttg ctaaaagaca
    26401 tatacacatg actcctaaag atgctgaaaa attcaatgta tgtgataaag agatagttga
    26461 agccaaggtg atgggtcaaa gacctttaac atttgatgat gtagtaataa gagtgagtga
    26521 cagttttaaa acttatatgc atatagacta tgatgaagcc aatgcatgtg gttattcaaa
    26581 aggaactgtt gctaaaataa taaagaaagc ataaatttaa cctactatat aaattacctc
    26641 tagggaggat ttaatatgaa ttatgataac cttgtagatt taataacgga agaaatctat
    26701 aaaaaaataa atagtaatga aataaaaata tctaataaac ctaaagctgt gattgtattt
    26761 gaacaagata acaataaatt taacttatta aaagatgaat ttgaaatact agaatttgat
    26821 aaaagtataa gggaatgtga aatagtgata gtttcaagac tttgtatgag ggggctatcg
    26881 aatatagcac ttggaaattc aacaagtgat gaagaaagat ttatactaaa aatgattatg
    26941 aaaggcaaaa aagtatatgt cctagatgaa ggaattgaat acaaaaaata taaggatact
    27001 gcaccaaaag cattatataa gaaatttatg tcatttgaag atgaaatatg taaatttggt
    27061 gtagaaatta taaaagactt aaatgttata actaaaaata agttaaatat aaagaaagaa
    27121 ctagaaagta ctagaggttc taaaaaagaa gatacaaaag ttttagataa agatgtttta
    27181 aatttaacca gtgtagaaag tgtaaaaata gataatgaat ttagtttgga tttaaggaat
    27241 aaaaaactta tatcggaagc tgacttaaga aaaccaacta taaatggagt taaaaacata
    27301 ttagttaata aaaaaagtat aataacacca ttagctgtag attttatgag aatacaccat
    27361 ctcaaactaa agaaactgta aggaggtaat tttatggata taggaaaagt tgtaggtaat
    27421 gtttgggcta caagaaaaga tgaaaaatta tgtggccaaa aacttttagt tgtaaaaatt
    27481 ttaaaaacta aagacacata caaggaaggc ttcatggttg cagccgataa tgcaggagca
    27541 ggaaatggag acttagttct tatatccaaa ggttcctcag ctagagagtc gattgaaaaa
    27601 tctcatgttc cagtagatgc aactatagtt ggagtagtcg attcgtttga ggtgtttgat
    27661 gaataaaagt ataggagcta tagagtttaa aagcattgct aaaggtatag aagtatccaa
    27721 tgaaatgata aagaaatctt cagttgatgt attgtactta aaaagtattt gcccaggtaa
    27781 atttctaata atagtaggtg gagaaacttc ttatataaat gaatgtgtag attatggaat
    27841 aaaacttgga gaaggatata ttgtagataa cttcgtaata aatgcaattt cacaagaaat
    27901 attagatgga tttaaaaata agtatcaaaa gctagatagt atagtctcta taggcgttgt
    27961 tgaaagtagt aaagtatgcg ctggaataaa aatgcttgat aagactttaa aatctggcga
    28021 cttagtatta gtaaaacttc aattatcttt tgctataggt ggcaaattag tatatgtagt
    28081 agcaggagat ttaagtagtt tagaatatgc attaaaagaa agtgaaaatg tagtaagaga
    28141 aaaagaagta atatataaga ctgtaatacc atcagtagac agtcaaataa taaaaagtct
    28201 aataaaataa tggggggaat tatgagtata aacgaaatta taatctatgt aatggtagtc
    28261 ttcatggtac ttggagctat agataaatgt ataggtaaca aatttggtct tggagaacaa
    28321 tttgaagaag gtataatggc aatggggtca cttgcagttg caatggttgg tgttatatgt
    28381 ttagcaccag ttcttgctga tgtattaaga ccaattgtag taccagtatt taatatactt
    28441 ggagctgacc cagctatgtt tgctggaagt ttattagcta atgatatggg tggtgcgcca
    28501 cttgcacttg aacttgcgaa agaccctaat tctgggttat ttggtggatt aatagtaggg
    28561 gctatgatgg gacctacaat agtatttata ataccagttg cgcttggaat aattgaaaaa
    28621 gaagaccaaa aattcttagc aacaggaata cttgcaggta taataacaat acctattgga
    28681 gcattcgttg gtggattagt tgcaggattc gaggtaatga tggttcttag aaacttagtg
    28741 ccaataataa tatttgcagt agttatagca cttggattat taaaattcga aaatgctatg
    28801 ataaaaggat tcacatactt tggaaaaggt gtagtaatag ttataacttt aggacttgct
    28861 gctgccatag ttgaagcttt aacaggaata gttgtaatac ctggaatgaa accaatcagt
    28921 gaaggtatag aaatagttgg agatatagca atagttttag caggagcatt cccattagtg
    28981 tttgttataa caaaggtatt taataaacca ttaatggctt taggaaaagt tcttggaatg
    29041 aatgatgtat cagcagcagg ccttgttgca agtttagcta actgtatacc aatgtttggt
    29101 atgatgaaag atatggacaa tagaggaaaa ataataaatg tagcattctc tgtatcagca
    29161 gcattcgtat ttggagacca cttaggattt acggcaggat ttaattctaa tatgataaca
    29221 ccaatgatag ttgctaaatt agttggtggt ataacagcag tattgttagc tatggttatc
    29281 gcaaataaga cactaaggaa ggagaatgta taagatggat atatcaaata tagataaaaa
    29341 tttaattgaa acattagtaa gacaaataat agaagaaaaa ataagtggaa ctaaagacac
    29401 agtagatttt gttagaaata aagacattag tggaataact tctataaagt taccaactgt
    29461 aaaagttagt gaatctgata gattagatac agggaatcca agtgatgtag tttacacaaa
    29521 agatttattt acattagagg aaagcccaag attaggttgt ggtatgatgg aaatgaaaga
    29581 aacaactttt gattggactc taaactatga tgaaatagat tatgtaatag atggaacttt
    29641 agatataata atagatggaa gaaaggtttc tgcttcttca ggtgaattaa tattcatacc
    29701 aaaaggaagt aagatacaat tttctgtacc tgattatgct agatttatat atgtaacata
    29761 tccggcagat tgggcatctc aaaattaata aaaatcaagt taagttaata ataatcaaat
    29821 aaataattta aaatacaaac tcttaaataa acacacatat ttaaaaaagc tatgaattaa
    29881 aattcatagc tttttttata aagaatgtta tattttagac gtattttttc tatatttact
    29941 gggagacata ttatattttt tattaaataa tctaataaaa tgctctacat ttggataacc
    30001 aatactattt tactgataat cttttcctta tcactaatct tacattttaa aatattattt
    30061 ttactcgtaa tattatcata agaatttgtt tcttatttaa aactaattag aattataaag
    30121 tttattgcca tgttattaat aaaataaatc cagttaaatc gagtgctagt taaagtaata
    30181 agaaactttt acaatggttt cctttatcga ttgaaataaa agttaatatg gtataatatc
    30241 taaagagaga atcttatcaa ttagaatatg catagaaaca agtggcttaa aaggagacgt
    30301 tatatggaag agatagtaaa gaaggaacaa gcaagtatga atgatatttt tttgtatctt
    30361 aaagctaaat caaactcatt atataaattt gtaatattat ataatgagtt tatcaataaa
    30421 cctaaagatt atggaactgg ggaacttata aacatggttg aagtacatat gctaacagcg
    30481 attgaagaaa atccaggaat aagtccaact cagttagcta aaatatggaa cagaactaaa
    30541 ggtgcaatat ctcaaactat atctaaattg gagaaaaagg gttatataac taaagaaaag
    30601 aaagaaggaa atgcaaaaac tatattacta tatccaacca catcaggagt agagttaagt
    30661 aaggcacata aactatatga caccatagat gttacaagaa catttgaata cttaatcaag
    30721 gagtgtacat tagaggagat agatagtttt tataaagtaa ttgatttgtt tattaattta
    30781 ttagaagaat ctccgcagga aaataatgat tctgaaaaag tgtagctaag attgaagttg
    30841 aataaagaga aatagatatt atagaagtag tacttaagta cacattatat aaaaatataa
    30901 taggtatagg attaaaaagt ttagtggttt aaagtttaac cactaaactt ttttaatgtc
    30961 tataatctac tattatttaa tttactaaaa ataaaaaaac tcattatatt aagatgaaaa
    31021 tagaaaaata actagaaaaa tactataata tatcagctta atacagaaaa aagttaaaaa
    31081 tattgagaaa aataaaaatg aaaacgtttt atattgacat agagaaaaag tagtgatacc
    31141 atttaaatat agtttagtag ctaaactata tttaaattat aataactatt ttagggggat
    31201 gttatgaatt taaaacaatt aagtgaaaaa tacgaagaat atgtaattca aatgagaaga
    31261 gaatttcata agtatccaga attatctttt aaagaaataa gaacaaccca aagaataagg
    31321 gaagaattac aaaaaatagg ggtccctttt gtatctattg aaccaaatat cgtaatagct
    31381 actatacaag gcaaaaatga aggtaagaca attgcaatta gaggagatat agatgcgctt
    31441 ccaatgcaag aagattcaga tgttgaatac aaatcagaat atgatggaat aatgcattct
    31501 tgtggacatg atgctcatgg agctatgtta ctaggacttg cacatatgct aaatgatata
    31561 agaaaagatt taaaaggtag agtattatta gtttttcaag cagctgaaga agttggtggc
    31621 ggacacaagg agataataca gtactttaag gaaaatggag gaccagatag attaatagct
    31681 actcatgttt ggtccgatat tgaagctggt aaaatttctg ttgaaccagg acctcgtatg
    31741 gctggtgggt ctggttggag aatagacata acaggtagag gaggtcatgg ttctagacca
    31801 gatcaaagca tagatcctat aaagccagct tgtgatatag ttttaaaagt atcttctata
    31861 ccagttaatc atataagtgt actagaacaa tgtgttgtac atgcatgtgc aatacatgga
    31921 ggaactacaa taggaaatgt tattccaaac aatgcagagg taataggtgg atatagatat
    31981 tttactgaag aatcaggcaa aaaagtgttt gacattataa agcaaatgag taatggtgtt
    32041 ggacaagctt atggagtgga tgtgaaggtt actcatactg gaggcatagg acctgttatc
    32101 aatgatgaag aagcagttaa gatgtctaaa gaaatagttt ctaatataga tggattggag
    32161 ttagattctt atgagccaat atgtgcatca gattgttatg gtgaaatatt aaaagagtat
    32221 tctggttttt attgttatct aggggtaggt aacaaagaaa aaggaataat atatgcacaa
    32281 caccatccta agtacaatat agatgaagat acattaaagt taggttgcga atttatggct
    32341 aaatatgcag ttgaattttt aaataaaaat aataactaaa ataaatcgaa ttttataaat
    32401 gggggggatg aaaatgcaag gtgcattaaa ggaaaataag aaaaaaagtg gtggaggatt
    32461 tttaggatgg attgaaagag ttgggaataa aatgccacat cctctagcat tatttacata
    32521 tattacattg atagtagtag cattatctgc aatagcaagc tttttaggtt tttcagcaac
    32581 aagtcctgct acaggaaagt taataaaagt tatgaactta ataagtgcaa aaggtttagt
    32641 actatttatg caagagtttg ttaagaactt ccaaaacttc cctgtgcttg gggtagtttt
    32701 agttatggca gttgccacag gagtttgtga aaagacagga tttttttcaa ctgccataaa
    32761 aatgagttta tcaaaagtta aggggaatgc ggttgtattt ataatagctt ttataggagt
    32821 atttgctaat caagctggtg atgctgcttt tgtattagta ccaactcttg caggagcaat
    32881 attttatgga ttaaatagaa atccattagc tggtatattc tgtggatttg catcagttgg
    32941 tggtggattt gcaacagctg taattcctgg gggatgggac gttacgctaa cgccaataac
    33001 tgtatcagct gctcaaacta ttcaacctgc atttgatatg acattattag ctagttatta
    33061 tgcactattt gtatctgcgt ttatagtagc tacagtatca acaatagtaa cggttaaatt
    33121 tatagaacct aaattaggta agtatactgg taaaccagaa ggtatagatg ataatcaagg
    33181 ttttgaggtc acaaaagaac aagcaaaagc agcaaagtta gcaggtttta cagttttagc
    33241 ttatgtagcg ttattaattg ctttgtgtat accagctaat agttttttaa gaagtccaga
    33301 aggttcttta atatttggag caccacttat gtcttgctta cagtttttta tagtaatact
    33361 attcttcttg ccagggattg tgtatggaat gagggttggt aaaatcaaga ctgtaaaaga
    33421 cttaaatgat atattatgtc aatcaatggc agcaatggca ccgtttatcg tacttgcaat
    33481 agttataggt caattcttaa cgctattctc agtgtctaat ttagcacagg tactagctat
    33541 aaaaggtgga gcattactca actcattgcc actaccacca caagttataa tactgctatt
    33601 cttagtacta gtagcgttta taaatatatt tgttataagc ggaagtacaa aatggatgat
    33661 atttggacca gtatttgttc cgatgttaat gcaattaaac atacatccag catttactca
    33721 gtttgtatat agattaggag attctgtaac taatcattta tcaccattaa atgcattctt
    33781 tataatactt ttagcaacag tccaaaaata cgataaaaat gcaggtatgg gaactatatt
    33841 ctcagctatg ataccttaca ctataggtta ctttgtagta cttgcagttt tagtagtagt
    33901 ttggatgaca ataggtatac cagtaggaat aggtggacaa gtttggttat aaaacatatt
    33961 taataatttt gggaggaaag aaaatggaaa caactgaaat aagatacaat tttgatgaag
    34021 taatagatag aagtggaaca aactgtctta aatatgatct taagagtcaa tttatgccag
    34081 aatctccaga agatgcacta ccactatggg tagcagacat ggattttgca tgtgctcctg
    34141 agataattaa tgcaatgcat gaaagaatag acagaaaaat atttggatat agctctcaac
    34201 aaactgatga ttattatgaa gctgtatgtg gatggtttaa gagaagattt gattggaaaa
    34261 tagaaaaaga gaatatattc tttagcccag gggttgtgcc tgcgttagga tttttcatac
    34321 aaatattaac acaaaagggt gatggtatca taatagaaaa gcctgtatac tatccttttg
    34381 aagataaaat aactaataat gaaagaaaag tagttaatag tcctttaaag tttgaagatg
    34441 gtcattattc tatggattat gatggatttg aagaattagc taaagatgaa aataataagg
    34501 tgtttatatt atgtagtcct cataatccag ttggtagagt atggaaaaaa gaagaactta
    34561 gaaaaatagt agacatatgt aagaaatatg atttgtggat aatatctgat gaaatacatt
    34621 gtgatattat tcgtaaaagt gaaaagcata taccattaga agtagcatgt cctgattata
    34681 aagatagaat aataacttgt acagctccaa gtaagagttt taacttagct ggtatgcaat
    34741 tatcaaatat agtaatcaat aataaggaat tacaagaaaa atggatgctt gaaacagatt
    34801 ctaaattagc tatattccta cctaatccat tcgcaatagt tgctactaaa gttgcttata
    34861 atgattgtga agattggatg aatcaagtaa atgagtatat agatggtaat attaaatatg
    34921 tagaagattt tgttaatgag tatatgccta aagtaaagat aataaaatct caaggaactt
    34981 acttaatttg gttagacttt agagggtatg gattagatgc aaaacagctt gaatatgtaa
    35041 tgcttaacaa ggcgaaggta ttgctagatg aaggatacat attcggagaa gaaggagcag
    35101 gatttgaaag aataaatgtt gcttcgccta gaacaattat agaagagtgt atgaatagaa
    35161 taaaatgtgc atttgaagga ttataatagt aatatctaaa taatatattt gtgtatttta
    35221 aaaaaagact atgttaaaaa aatatttcaa agcatagtct tttaaagttt tatgatgagt
    35281 ttaaaaaatt tcaaaacgtt actattattg ataatcttca cttatatgtt tatattagaa
    35341 ataattccac aatatgctca ttttctaaag ttgcactttt atacaccttg cttcaccaat
    35401 atcatgtgta accaaaatag tagacttatt ctcattctta ataatactat aaacatcatc
    35461 acaaactaat aatctagtct gataatcaag agctgaaaaa ggttcatcta aaagtagaat
    35521 atctggattt acagaaagtg ttctaataag cgcaactctt tgtctcatac ctccagataa
    35581 ttcttttgga tacatacttc taaaatccca taatccataa gtctttaaaa ggctttcaac
    35641 tctatctaaa gattttttat cttttttgcc ttgaatttcc aatccaatag ttatattatc
    35701 cattatattt ctccattcaa gcaaattatc tttttgaaac atatatccaa tatttccagt
    35761 aatctttata tcaccactag tcggttttaa aagattagta agaatattta atattgtaga
    35821 tttaccactt ccagaaggac caagcaaagt taatatttct ccttctttca agttaaaatt
    35881 gacatccttt aatacttcaa gctcgccttc cttagtgtag aagttcatat ttatattttt
    35941 aacttctact atgttgtcat tcattatgcc accccctata acttttagct cgtatatatt
    36001 atgttattaa caatatgacc tatttgtacc atttttcata aatataatat aaatattttg
    36061 tttatttacg tattttctta gtaacttgta cgtataaatt ataataaata aattataagg
    36121 taggggataa atttgagtaa cataataacg aatttaatag agtcagtatt tactaatcca
    36181 ataactatat tgtttttact tgcaataact gtgtattctg tttttaaaat aatagaaaat
    36241 aacagagtat attcatttgt aagttcaaaa ttagacgaaa tcaatagaga ttataagaca
    36301 agtgagtttt ataaaaaggt aagggatgac tactatacat atagtaaaga aaatccttat
    36361 gcagacgtaa atataacttc atttatagag gaagttgtat ctgatttaaa gcataataat
    36421 ttgccattgt tagaaaaaat tagaagtata aaaaattcat cttcaataag tatattactt
    36481 ggggttttag gtacgtttgt tggtctttct acaatgcttt tatgtgttga tactaaagac
    36541 attataaatt cacttccttc aactattagt agtatgcaaa ctgcatttac aactagtata
    36601 tttggagttg tattttctct aattataggt tactttacta agataaaaga ttgtgaacat
    36661 gttttgatac aaataatgtt aaaatctgaa aatttactaa catctgaaat aactcatttt
    36721 aagtcagaaa gaatggattt aaaagtagaa gaggtaaaaa atacaataaa acaaataagt
    36781 aagtctatag aagctattga aaaatttgat aaaatatcta aagatttaaa tgactttaat
    36841 gatgaattta tcagtggtat agaagcttta aaaagccttt tagaaggttc tcaaagttct
    36901 attaagacat ttgaccagag cgtaagaaaa ttagataaac agtttaatat tttaaatata
    36961 aaatttgtaa agctttttga taaatatgat aatcaagata atataaataa agagatttta
    37021 tttgatataa aagaatcttc aaaaaatata tacaatgcca ctgaaagcca attcaaaatt
    37081 agagattata taaaaaatat aaatgcagga tttgctctat atgaaagaag tgctcaagat
    37141 ttattaacta aattaatgac ccatgaaaat aaaatctctc aaaatcaaaa aatcctttta
    37201 gatgaaaagt ttaccttaga tgactcaata aaaaatctct caagtattat tgaaaacttt
    37261 tctaatgacc tacaagttaa actggatatg atgtttgaaa attctttaga tattcaagat
    37321 aagttagatg ttatgtttaa taactctttt atgaatgatg aagttcctct tgatagtgag
    37381 gaattattta aggatgatgt taataatgta tttaatcctt ttagtgaaga aatttatgag
    37441 atagaggata aagaaataaa ggtcataggt gaggatgagt taaatgaata ataaatatag
    37501 aagaactgtt aacagagaat ttgaaaagag tagcttttgg ccaacattta cagatttatt
    37561 atctactgta ttgatggttg tgattcttat cttatttagc tcagaaagta tttcaggttc
    37621 tgttgaacaa gatttagcta agaatgtcaa tgcttctgtt gaagaaactt ttaaaaaaag
    37681 caaaatacct gtgaaggtag ataaatctaa tgggcaagta acttttggtg aaaaaaccat
    37741 gtttgatgta gatagtgatg ttttaaaacc agaggctaaa gaaatgctaa aaatgtttgt
    37801 tccaaagtac atagagacta tttataaaga ttatggtgac tatatatcca aaatagttat
    37861 agaaggtcat acagatgatg tgggaagtta tatatacaac ttagatttat cgcaaagaag
    37921 agcatatagc gttgctaaat ttatagtggg agatgaaata ggtgactata aatacaaaga
    37981 taaagtgact aagcatatta ttgcaatagg aaggtcaaaa gctgaactca tcaaaaatgg
    38041 tgacaatagc gtgaatagag atgcatctag aagagtagaa ctaaaatacg aaataaatat
    38101 taatcaaaat aaataattaa atttttataa aaaaaaagaa ggcagttggt gtgagcttta
    38161 agccttcttt aaggaaaaag tttatttatt tttgttgata cttaacatat tatagttttt
    38221 agaagcagtt tgcaatatat taaacgtaaa tggtcgttta aaatgcataa ctggatacta
    38281 ctgatgtaaa atatttcatt ttatataata taaaaattat acagtgtcaa ttttctatat
    38341 tattgtacta taatctatta tttaaaatat tatgtaaaaa aatatcataa aaacgcatat
    38401 catgttataa ttactagagt attatgaata tggaggcgta gtttgtgata gaaataagta
    38461 taaaaaataa aaaaaattct aaaattaaaa ctttgatact tttattgata gtatctatat
    38521 cgatttattt aactggttgt actacatcag ataatggaaa taatcaatca aataataatg
    38581 attctttgtc tagtagtata tcaagtgata agaatgtaaa aattcatttt attgacactg
    38641 gaaatagtga tgcaatattg attcaagatg gtaaaacttt tacattgata gatgggggag
    38701 ataatgatga tgagggatta atggtagatt acctaaacaa tcaaggtgta aaagatatta
    38761 aatatcttat agctacccat tctcatgcag accatttagg tggacttgat tctgttgtca
    38821 aaaactttaa tatagaaaat gtttttgtat cgaatggttc agcagaaaca aagagttata
    38881 gggactttat aaatgcttta gcaaataagg gtttatcccc aagtgtaccg cttgaaaata
    38941 ataagttcta tttagaagat tcttattttg aagttctaaa tacaaatggg ggagatacta
    39001 ctaatgaaca atctctagtc cttgtatata ctaatgggaa tgataaagtt ttatttacag
    39061 gtgatgctga agaaggtacc gaaaaagaaa tactacctaa gcttgagaaa gtagaccttt
    39121 taaaagtagc tcatcatggt tctcgtagta gttcatctca agagttttta gataaagtaa
    39181 atcctgaata tgcggttctt ttagtaggca agggtaattc atatggtcat ccacatcagg
    39241 agacaatgaa taaattgaaa aaaatgggag taaaagtaca tagaagtgat gagtgttcag
    39301 atataatatt tgaatcaaca ggtgatggag tatttacaag ttgtaaagat ggaagttata
    39361 ataaaggtgt tagagaagat ggaaactctg gaaaatcaaa cagtaataca agtaaaaatg
    39421 attcttttaa aaataaacaa aatacattca attcagaaga aatagtgtat tttactccaa
    39481 aaggtaagag ttatcactct ataaaaaatt gtagtgggct ttcaagaagt aaaaaaatat
    39541 tatcaggcac aattgaagaa agtaagaaaa atgacccatg tgatatatgt tatggaaaat
    39601 aacaaaaaaa caaccaattt atctataaag cttctgaact ttaaatcatt taaaaaataa
    39661 aataaatgca taaaaaaaat aagctataat caatagataa tacatttcat ctatacgaat
    39721 agcttatttt tttaagtatt ttttaatagc tatttaataa ctctaaatac accagttaca
    39781 atacctacaa tttcaacttc tgagtcattg agcataattg gttccataaa atcattttct
    39841 ggctgaagtc ttattaaatt tccttcttta aaaaacctct taactgtagc agattcacca
    39901 tttataagtg caactactat ctgagaattt aaggccgtat tttttttgtc tactacaacg
    39961 taatcttcat ctaaaattcc tgcattaatc atactttcgc cttttactct taatacaaaa
    40021 ttgttactgc cctttactaa actggcaggg aatggaatgt attcctctat gttttgttga
    40081 gctaaaatgg gttctccagc tgttatttga cctactaaag gaagctctat tatttcttga
    40141 ttagctccag aaacatcatt tactttacta cgttctaaaa cttcaatagc tcttggttta
    40201 gtagggtcct ttcttatgta tcccagtttt tcaagtttat ttagatgaga gtgcacagtt
    40261 gaagtagatc ttaaccctac agcagtacat atttctctta cagcaggtgg ataacctttt
    40321 aatgtgattt gagactttat aaattccaat atcaagactt gcttttcagt tagatctaaa
    40381 tacataacat cactcatttc caaacatatt ttgtttttat ttccatacac tttatatttt
    40441 taattataac ataatccatt tatatctgca aacatttgtt cctgattttt aatcgtcctc
    40501 aatccattca aaattcttga ctatatcacg ttttacattt ttcttatgag ctgcataaag
    40561 ctgagtagtt gtgacattat catggtcaag taagttttga acatcatata tagaaaatcc
    40621 tgtttggatt agagaagttg cagccgttgc tcttaattta tggggactat atccattgtc
    40681 tctagtagta tcaagtggaa tagatgtata tttttttacc agtgttctta tagcctttgc
    40741 tgtaattctc ttattttgaa gagacaaaaa taaagcatct ttttcttcat catttaatag
    40801 ttcatctctt gttctttcgt tttgcaaata atcttttatt acatgttcac aagtatgatt
    40861 tataggcatt aaaacttctt tcccacgttt tctatatatt ttaaattcac ctcttgaaaa
    40921 attaaaagag gagatattga gttctctaag ctcatttaat ctaagcccgt atgtaacaaa
    40981 taatgctagt atagctttgt cacgtaattt agtttttctc caatatacct tttctttctc
    41041 tgtaagccct tcacctgttt ctactgattc aagcatctta gcaacttcat ctatctcaag
    41101 gcgcttaata gcatctggct gaggtttagg aagttttatt ggattgaatc catcagttat
    41161 attattatct atctgagagt ttctgtataa gaatttaaat agagtagaga tggatgattt
    41221 ttttcttgct aacgctctat tgttattttc aaaaatcaat gtgttttttt ctgtattttt
    41281 gtaatatcta ctgcaataat cacctaagaa taaatttata tctcttgatt ttattgtatt
    41341 aaaatcatct tctgtaatat cttttacaca atctgcattt gttaattctt tggtttcaat
    41401 caaatatgaa caaaaaaaat taatatcttc taaataagca agtcgtgtag aaactgcaac
    41461 agaacctttt aaatatataa aataatcctt cataaataca ggaagtttat tttccaaaag
    41521 tagacatttt tctatgagtt cattttcttt gataacaata ttatcaggtt tatctgattt
    41581 attatgtact tttataattt tcttatcatt attcaaaatt aaacctccta aaactaaaat
    41641 ataaatcttt tatattattt tttgatattt ataccaagtg agtataaata tttaatttaa
    41701 tcatttttta catttttaag agattagcag tgctttagat gaaattatca ctaactattc
    41761 cctaaatcca catttaaaga ctagttgaat ttaagtactc tttttttatt tctcaatata
    41821 tttatagaaa tattttaaaa tatattgaga aattttttat gctctactaa aatctttttt
    41881 atataatatt tttatatatt tctaacgaaa ccaaatatta gtaaaatatg tatttattta
    41941 actaaagttt ttaaatgggc tgactaagct taaaatatag gatattatga gagttactat
    42001 tgaaaaaata aaccctattg ccataaagaa acttataaat atgttatact taactattaa
    42061 actggatata ttcaagttat caaatccaaa taagtatgta attgaactta ttacaaaaat
    42121 aactataact ataaagctca gaccatttaa gctatttttt aaatcagcac tactaagtga
    42181 catatgtgta gatatagaat acattaaaaa cataaatata aaatacttca atgaatatac
    42241 actaggtgtt aacaacatta ttcttataaa attggaaata tcacctaaaa taatgtgtat
    42301 aaaaccattt atatttaaat tattaatcat acttacatat aactttaaat ctatattttg
    42361 agtcactttc atataactat ctggcagtaa tatcttaaaa attaaaataa tcattattgt
    42421 tccacctata ataggtgcaa ttcctataaa gaaatttcct atactttgat aaagattatc
    42481 ttttttatag ctatgactta catatcctag tataccatca tttttacttt ctattggtct
    42541 gaaaaactta actgaattta ttttatgcat gaaaatcaag cacattatca aatgactcaa
    42601 ttcatgaaca aacgttccta tagctccagt tacaataatt ccagtttttc caaaagatga
    42661 aaagataaat ttattattta gattttctgt aatgctaaaa atcaatccaa atacaataaa
    42721 tattcctatg aaacaaaaaa tatttattac acttattttt aaaatttcga ttatataaat
    42781 cataagttaa gtcctcatgt aaaagtattt aactactcta cttcatatcc attacagctt
    42841 aaaattttac aagcatcttc tatatctttt tcttttacta agatatagtc tgtatcatac
    42901 gtagaaattg caaatatgct tattttgttg tctgctaaca aactacttaa cttagataaa
    42961 attcctacaa gtgaaaagtc taaaggacct agtatcttaa gtattctcca ctccttttct
    43021 gacttaacat cagaaggaat attattattt aaacatacaa cacttaattc atcatcagtt
    43081 ctagttatag agtaaaactt ctctgtatct atccatgttg gtattttact gtcattattt
    43141 aatctacata ctgcatactc ttctaccaat aattttaatt tcataatgta tatttcctcc
    43201 aatcttattt gtttacttaa gattatacat taaaagttac ataaaataaa acatataaag
    43261 taaaaaaggt tcactatagt gtcctatttc tatagccaac ctttaaaact taattaaatt
    43321 ctaataaaga gatatattat ctaggttcaa ttataagttt aatggctgtt ttcttatcac
    43381 cttcgatttc tatatcagta aatgcgggaa tgcaaactaa atccattcca ctaggtgcaa
    43441 caaaacctct tgctattgca attgatttta tcgcttgatt tagagctcca gctcctatag
    43501 cttgtatttc tgcaacgcct cgttctctta gtactccagc caaggctcca gctacagaat
    43561 taggattaga ttttgatgaa acttttagta cctccatttc aacatctcct tgttaatttg
    43621 ttaaagtatc cattacctaa agtactaaat cataattgcc atttactaat tacaatcatc
    43681 atttaaagta tacttttata aaaatatact tctataatcg ttttaagaaa acctttattt
    43741 tttttaacca ttttattatg aaaaaactac aaatttcttt atattctata agcattttcc
    43801 aatatttcta aattttttat atctttgagc tataatttcc tctttatcca tatctttgta
    43861 atgatttaat ctttctaaaa tataagcttt tatttctttt gaaacagctt ctacatcttt
    43921 ttgtgctcct ccaagaggtt cttttataat cttatctatt atttttaaat catataaatc
    43981 attacttgta agcttcataa catcacaagc ttctttagct ttagatgaat ctttaaatag
    44041 aatactagaa agcccttctg gagaaatcac agaataaact gaatgttcta gcatacaaac
    44101 atcatttcct actccgatac ctaaagctcc tccactacca ccttcaccaa ttacaaaagt
    44161 gattactgga acagaaagtt tactcatttc aagtaagttt cttgcaatag cttctccttg
    44221 tcctctttct tctgcttcta aaccacaaaa agctcctgat gtatcaataa acgttattat
    44281 aggtctatta aatttttcag cttgtttcat aagtcttaat gcttttctgt atccttctgg
    44341 atgaggcatt ccaaaatttc tttttatatt ttcttttgta tctcttcctt tttggtgtcc
    44401 aactatagta acattaaact ttcctatctg accaatccct ccaaccatag aagggtcatc
    44461 tttaaaaagc ctatctccat gaagttctaa aaaattagaa caaatatgtt ctatgtattc
    44521 caatgtcgta ggtctcttta tatctctact tagtgttacc ttttcatatg ctgatagatg
    44581 tgaaaaagca tcttccttaa gcttttccaa tttctcatta agtgaattta ttttatcact
    44641 taaatctata ttatttgcct tagaaatagt tattaattgt ttaatatcat tttctaagac
    44701 ttttattttt tcactattat tttcaatcaa aacagttcct cctttatgcc ctatttcttg
    44761 tgcatagcaa gaatttgata taataattcc ttcatttttc ttctatctac tatcatgtca
    44821 ataaaacctt tttcaagtaa aaactcagaa gtttgaaatc cttcaggaag tttttgattt
    44881 attgtttgct ctattactct tggacctgca aaacctatca acgtatttgg ctcagaaatt
    44941 ataatatcac caagcatagc aaaactagca gttactcctc cagtagtagg gtcagttaga
    45001 actgatatat atggcaatga tttttcttca agcttagaaa gtgcttgaga agtctttgcc
    45061 atctgcataa gagataccat accttcttgc attctagctc ctcctgaagc agaacaaata
    45121 attataggta aattattttc agcagcatac tctattgaat aagttatttt ttccccaaca
    45181 atagaaccca tacttcccat cataaaatca ggattcatta cacaaataac tgttttaatt
    45241 ccatttattc ttccataacc tgtgacaaca gcttctgact cttttgtttt ttccttataa
    45301 gagtctactt tttctttgta tttaggaaaa tttagtggat tttgaaattc tacatcagaa
    45361 ttaaactcca taaaagttcc tttatcaatc aataaattta ttctttttct tgctcttaag
    45421 ccataatgtc ttgaacattt tggacataca aatgaatttt cttctatgtc ctttctaaat
    45481 acatgactat cacaaccttt gcaataggtc caaaatttat catctacact attcttttta
    45541 aagttgtcat ctaaagaaat cgtaacatac ttagattctt ttgatgataa aaattttttt
    45601 atcataatct atttactcct tataatgtag caaattcttt cttcataaag acatcttcta
    45661 taaatttggt atgatgagta tcttctctaa actcctcact tgttacaagt gccttttgaa
    45721 attctacatt tgtattaata ccttctacaa taatttcgtc tagagctcta tatattctac
    45781 ttatacattc ttctctagtt tcagcccaac atattaactt acctatcata gaatcatata
    45841 aaggtggtat agtatatcct gcatatacaa aagtatcaaa tctaacacca aaacctccag
    45901 gtaaatttaa tgattctatc ttacctggtg atggagcaaa attctttgat gaatcttctg
    45961 catttattct acattcaata gcatgacctc taaaagtaat atcttcttgt ttaaaaggaa
    46021 ttttatcccc attagctata gatatttgaa gttttataag gtcaagattt gttaccatct
    46081 ctgtaactgg atgttcaact tgtattcttg tattcatctc tataaaataa aagtttttat
    46141 ctttgtcaac tataaactca atagtacctg caccgatata acctactcct tttactatat
    46201 ctactgcaat tttatgaagt ttttgtcttt cttcatctga aaggtatgga cttaaagatt
    46261 cttctattac tttttgattt cgcctttgca tagaacaatc tctatcacct aaatgtattg
    46321 catttgaatg tttatctcca aatacttgta cttctatatg tctaggattt tctataaact
    46381 tttccatata taaatcacta ttagaaaatg ctgctagagc ttctgaactt gccatatcaa
    46441 aatttgaaaa aagttcttct tcttttctaa cgattctcat accttttcca ccgcctccac
    46501 ttgaggcttt tatcataaca ggatatccaa tttctcttgc aacttctaaa gcttcttcct
    46561 tagttttcaa aacagattct gaaccaggaa caacagggat attcaattcc atcatagttt
    46621 ctcttgctct agatttatct cccatcaaaa tcatttgttc tcttgttgga cctataaaaa
    46681 taatattatt atcttcacat tgctttgcaa attcaggatt ctctgataag aatccaaagc
    46741 ctggatgaat agcatcacac tttaatttaa gagcaagata gattatattt tctatattat
    46801 tataactctt acttatatta tttggtccta tacaaataga ttcatcagct atatatctat
    46861 gaaaacaatc tttatctatt tcagaataga tagcaacagt ttttatacct agttctttac
    46921 atgttctgat gattctaact gctatatcgc ctctatttgc aactagtatt ttttttatca
    46981 acttaaatac ctcctactac aatggtttta tcttaaataa aggttgatta tattctacta
    47041 gttcttcatt actaactaat acttcaatta tttcaccttt aatttcgctt gttatctcat
    47101 tcataagctt cattgcttct aatatacata aagtgtcgcc ttcttcaact acatcgccaa
    47161 ctttaacaaa gctatctgca tctggacttg gagaatcata gaatgttccc atcaaaggag
    47221 ctactactac tgatagattc tcattagatg tgacaggtgt atcgtttaca actggctttt
    47281 ctaaagaaag atccactact gattcttgtt gtacacttaa aacaggtgaa cttgtagatt
    47341 gagctttttt agatacttct aatcttaaat cgctactttc aagttttaca tattctaagt
    47401 tagttgagtc tatggccttt aataattcct taatttcatt gatgttcatt ttgttacccc
    47461 cttgtattat tacctggtgc taatattata tcacaaaaaa caaatttata aaagaaaaag
    47521 tgctgactag agaatcaaca catcaatata tcttttaatt ttaaattaac aaccagtaac
    47581 ttatatttgt tttaattttc cattattaat ataaattata agtataaaat gaataaaatt
    47641 caatattttt tgcaaaatac aagagaatac aaattaatac ctcgggaatt tttaagacaa
    47701 ataccaatat tatgcaattt agacttcgct ttctttcaaa ttagtatcat tttctttatt
    47761 tttacatagg atgtacttta atttagctat caaaacatta ctatataggt taaaagttat
    47821 tagaattgca ggaattataa agtaaactct agcacctata aaaccaaaaa ctactgtaat
    47881 aagtattaat cttttattta aagtaaaaaa aggtatatta aaaatacttt tgtcggatgt
    47941 ttctggagta taagaatata taactccaaa aatcaaagta agcatacaaa gtggaagtag
    48001 tgtataactt gaaattattc ccagaaatcc tatactttca aaatatttgc tagcactatt
    48061 tgtataaaca aacatgtatc catttaaata tgcgcatata catgatataa tgccaaaagt
    48121 tccccctaag gattgagtgt accaattaaa aaatttagat tccatatacc tcacctccta
    48181 aaactgtata tataatgata tgcatttaaa tagtaaaata tatctttata tgtttctgaa
    48241 taaaattttg ttaatttcat taatttatgt ttaagaaatt tgaagtatag tgtagtatat
    48301 attaatgtag atgaagtttt atagtactta tttcatagtg cttaatcaag ttatcttatt
    48361 atggattcaa aagttgtttg tagggtttta tattttgttg agctgaaaaa tttattataa
    48421 atgaagggat gttttcgctt tggtagatac attagaattt ggtcttaaaa ttttattttt
    48481 tatattatca ataatttgga tgggtaaaat aatgatttta agaactgata agcaaatagt
    48541 aatcaatcct ttgcttattg gtatatctgc agtccttgtg atgttgcata cctcacagag
    48601 taacattgaa ttttttggat tagatgtcca atatataaga atagttttgt atataatata
    48661 ttcactgata attttaatag gaatatgggc tactaacaga agaaatggaa ttttttagat
    48721 aatctatttc tataaaattt aaaggttgct agtaacaaag cactaatatt agcgttctgt
    48781 tactaacaac ctttattttg attatacact taaattgaaa atagaatgat tgaataagtt
    48841 gacatattat tttacattga cagtgattag aacttcttga gatgtattta aatcattttt
    48901 gtcgcttagt ataactttta ccacagcttg acctgtttta ttacctttaa ttatcatatc
    48961 ttcacatgaa agtacactct tatcacttac agatacaata aagtctaaat cttttggaag
    49021 attatcagta acttcccagt atttataata actatcaatt ttcttcgtaa ttatttttct
    49081 caaatcaata ctttcacctt ttgctatatc aacattatga tatttagagt ccagtttata
    49141 ctgattatct tttgtatcaa taaaatttaa atcgcaattt acatccacac cattatgaga
    49201 aagagaattt actacatcgt catcaatcaa ataattattg gcaagattta ttgaatccat
    49261 atcttttaga cttaaagctt ccttaggaac ctcttttata ttattattcc aaaaaataaa
    49321 attgtctaca ttttcaagat atgatattcc ttttaaattt gaaatgctct caccagttgc
    49381 ataaaattct ccatctaaag cctttatatt gcttatagtc atctcatctg ggtttatata
    49441 tctttttaca actgctctta aatttgcatc aggaaaaata tctttaagtt gattttcgct
    49501 caaaacctta tcatttgaat ttattggact taaagctgct gcagaaataa taaatggtat
    49561 taaattagct aaattcatag taccctccca cataaatttt ttattataat aatttaattt
    49621 ctatgagagg gttctgtttc cttgttatat atacctactt tcgtacactt tattaatata
    49681 aattaaaata aatttctact attaaactta taaacatatt actagttacg ttttttagct
    49741 tcacatctaa atattcgcat accttgtgac ataaatttgt cttcatactc tgttgtaaca
    49801 ttattttcat actcactatt tcctaaatca agagaaatat tctttaatag ccaattattt
    49861 gcagcaattt catttaaact aaactcgaat aatttttcat tatctgtttt aaagtgaatt
    49921 tcgccatcat cttccaaaac cctattgtac atttctaaaa atccagaatg agtgagtctt
    49981 cttttactcc atctattttt aggccatggg tcacagaaat ttatataaat tctcgataat
    50041 tctttagctt caaagtaatc caaaatattg cttacatctc cccataaaaa tagtatatta
    50101 ttcaaattag aagcatctgc tttttcaaca gcttttaaaa gaacttcttc cttaagttcc
    50161 atggcaatat aatttatgtc agggttctgc ttagctaaag ttgttataaa cttacctttt
    50221 ccagtcccaa attcaacatg tattggatta tcatttctaa actttaaatt ccacttgcct
    50281 tttaatttgt ctatatcgtc tcttaaaaca tattttgtat aacttaaaag cttttcatct
    50341 gcaccttttt ttcgtcttct tctcacaata attctcctta catataaaaa attagtaaaa
    50401 tacattttta ttatacatta tctcaccaaa aaataaaaag aactctctta aaatagaaat
    50461 ttatttctat aaagagagtt ctaaacttac taaaaactta atcttagtgg caccctgaac
    50521 aaccagagca tcctcctcca ccttgatctt tcatattttc aggaataact ctaaatccaa
    50581 atcctgtatc ttctattatt atatctccat actgactata ttcatcagag ctcattacaa
    50641 attgtaattc tccaacttca taagttaagt catcttcttt tttctcatct aaagctaatc
    50701 caaaagaagg acctccacaa ccaacacctg caaagtatac tcttatatta ttaggtttat
    50761 cttgattgtc ttttaagata ctttttaaag tatcaatagc tgtttctggt aaagtaattt
    50821 tcatcaaatc attccctttc aaatatttta ttaaaacaat atctattata tacccataca
    50881 aggtacataa tcaattagtt tttgcatatt ttactaaaac ttctacctaa tattacctaa
    50941 ggctttaaaa tattttatat aatattttat taccttaaat aaatacccta tcataaactt
    51001 agtaaacaaa taaaattatt attctaaaaa atataataat tttatttgtt gttttaatat
    51061 tataacacat ttgataatgt ccaattcata tatgcaaaat ttatatactt taaaatatct
    51121 aagaaattat tcaataaaaa aatactattt tttaaaaatt atcattattg ataaagctct
    51181 actatttata ttttttagtg tattcatgta taataagtaa aagcacaacg gtatatactg
    51241 ttgtgctttt ttgtaattaa taaacaatat tttggtctat aacaatgaaa aatggctact
    51301 ttccataatt gatttcatct gacataagca aaaagggtgt ccagctgggt caatcataac
    51361 tctccagtca tcagtaaatt gctcctctgc gattgtagct ccacaatgaa tttcatattg
    51421 aactgcttct tctaaatcat taacagcgaa atccatatga gccatttgct gttgagattc
    51481 aggtttttct ggccacacag gcggtttata ctcagaattt cgttgaaatg ttataccagg
    51541 atatgttccc tgatttgttc ctggagcacc aacacatgca tattcttcat tataaaatgc
    51601 tatttcccaa ttgagtaacg ctgcataaaa ttttgctaat tcatgtgggt ctttgcaatc
    51661 catcgtaaat gagtacattt tgattttcag ttcatcatgc ataacgtaat tacctccaag
    51721 tataaatttc ttcgtctttt catttttaag ctaaattcaa acattaagta tgtaatttat
    51781 ttcaagtatt tttctattat gccccaagcc tttgtttttt gcaatataaa gaaaaaatta
    51841 tatattttaa tattttataa ttgttgaaat tgtgtaataa attcaactgg atacatagtg
    51901 cgttttgaaa tttcttctaa agctaaacct tgttttaaaa gcctctttat gacgctttcc
    51961 atactttctg aaatttctat aatattttta tcaaaatcat aaaacctaaa agttctttga
    52021 ccccatgggt attcttttat ataatgcaaa aattcaatat ttcctattct atttatctta
    52081 ctttcccatt gtttgatatc attaacctca aaatacaact gaaagttatt tgattgttga
    52141 tatattggta aatcatatcc aattatagct ttataattac tttgtaatcc aaatccattt
    52201 tcaaatgata catgttctcc taaatctaat gtaatttttt gctccataac atcttcataa
    52261 aacttttttg atttatttat gtctttgaca attagcaata ctcctccaaa tttcatctta
    52321 tcactatcct ttctttgtta taagtattat aacttaaaat tttgcaattt cactgtaaaa
    52381 atcagacata ttagctcggt atttttgagg agttattcca cagacaattt taaaatcttt
    52441 aataaaatgt ggtatatcat agaatcctaa ttcattacat atatacatca atgaagtttt
    52501 attattgttt agaagtttta tagatttatt aatacgtacc aaacgagaaa atgacttcat
    52561 actcaaccct aggtactgat taaagagtct gtttaaatgc ctagaactat aaaatacttt
    52621 tttagaaatt tcttgtgaag atatgtttcc agagttttga ataatcaact gaattgccaa
    52681 aataaactca tatgagtatt caattttaat attagaaatc aataattctt ccaactttaa
    52741 aatcaattta tctatagata aagattcatt aaatattttt ttaatttcta aatctaatga
    52801 agtattaatt atagaaaatg gaacaacttt atcaataagt tcactttgct gtatacctat
    52861 aagcgggaaa aaaccagcag gttgaaattc tataattagt ataacatcac atctattagc
    52921 aatatttcct actgtttttg gtttagtagt tggaccaaat aatagactat gtaaccctgt
    52981 ggcatcataa aaaaacacca aagttacact tccatgagga ataatcgtgt aattatcaga
    53041 aattattgtt tgatttggaa acgatatagt aaaattcgat atccaatttt ttaattgcat
    53101 acaaggcaag agataaacaa aattgtcttc acaaactata agtgacctat ttttatttat
    53161 aaaatgaata ctttcttttt ttaacatata ttatatcctg tcctatcgtg aatatttatt
    53221 aaagtaagaa gaatccatat tatctctata tatcattaac tgcttttaat aatagagata
    53281 gtatgaatac tcattagata tttaataaac aaataaatta aaataatcaa taaaaaatat
    53341 agtactttta tctgttattt taatattata gcacatttat agtatttaac ttatatccac
    53401 tttacatatg tctaatttat atagttaaaa atgcttatct caaatacaat aattagtcct
    53461 tatacaatta aaccatctga aactgtaata gtacgactac tacttttggc tgcttctggt
    53521 gagtgagtta ccataattat agtttgtcca ttgtctctgt ttattttatt cagtaaatct
    53581 attatttcta tccctgtttt actatctaaa tttccagtag gctcatcagc aaataaaatc
    53641 tctggttttc caactaaagc tcgagctata gcaacacgtt gttgctgacc accagataac
    53701 tctcgtggtg tatgtttacg tctatcagtt aaaccaacta tatctaagat ttcatctaat
    53761 tgatttttat aatcttttaa atttttacca tctaataaca aaggaagcat tatattttcc
    53821 tccacattta aatttggtat taagttataa aattgaaata cgaatcctat atttctacga
    53881 cgtattatgc tcattttctc atcattaaaa tgtgatatat cagctccatt catatacact
    53941 tttccactcg ttggagtatc taaaccacct aaaatatata aaagagtact tttaccagaa
    54001 ccagattgac ccatgataga aacaaattca cctttcatta cttgtaaaga tacctctttt
    54061 aacactcgag ttgttgtatt tccaatttta tattctttga taatattttt tgcttctaca
    54121 gctaaactat tatgtgtaat tttcatatta acctccataa ttattcaaac ttaatttctt
    54181 ctatcagttt cattttcttc ccttttataa taggcactat cgaacctatt aaagttacta
    54241 taattcccaa taacccaaca ataataaatg ttttaaaatc taaatctggt ttcattgaaa
    54301 tttttggtcc tgcaactata aagatagttt gaatctcaag tatagatatc acaataccaa
    54361 taacagctcc aagtaaacct gaagtaaacc cttcaatcaa tgtcactttt atattttgtt
    54421 tatcacttag tcctatagat ttatacatag ctatagaacg ttttttttga atataattaa
    54481 tcagtagatt attaataata cctactgtag caagaagaaa aatgaaatag gtcatcttat
    54541 tcataggaga caaaaaacta cttatagtat ttaaagaatc attattaaat tcttcaactg
    54601 tacgactcca attatatgta tctccaaata aatctcttat ctgaatcata acaacatctg
    54661 gattgactgc tgtatatact aaaaaaccat aattagtttt atcaaaatca ttaactgcat
    54721 aatgtgatgg tataacagct tctacatcat ttgcacggga tttaaaacta cctactattt
    54781 tataagaaaa atcatactta tcattagata gagttattgt atctcctata gataagccta
    54841 ctttttttag agtatcttca ttcaaaataa cagaacgttt atcattaaaa gcttctatta
    54901 cttgtttttt tatctcaaaa tttgtataat tgattccaaa catagagtta tatagtttta
    54961 tattatctgt accctctagt cttgataatg ttacaccatt accagaaatc tcattattca
    55021 taacataaag aggtaatatt tttttaattc catccatatg tctaacattt tcaataaact
    55081 cttcattcat ctttccatct gcaaaacctt gtaattctgc gtcacgaaac acatctgtta
    55141 tataagtttt gacaaagtta ccaacaacac ttattgcaat aactgcagaa atacttataa
    55201 atagtaaagt gatattctgt attatatttt tgttattttt catatttcta gcagctaatt
    55261 taccctcatt ccctaaaata tttttataaa caaactcaaa aactatagac atgatatcag
    55321 taataagagg aatcaacaca atagtagcta caattaatcc tagtaatgaa aatccaccag
    55381 ctagatacaa tgtattttca ggggatattc ttggaagtaa aatagataaa ataaacatta
    55441 tacttcctat aaaaagtata gaacgatttg aaacattctt ttcttctact gttcctagta
    55501 caatattttt tattggcaaa tggctagctt ttttaacagg tatatatgca ctaaatgaag
    55561 aaacgattat tgctactata acagatataa tcactccaat gggtgatatt actactggaa
    55621 ttgatattcc ttgttcgaga gaatttccta acccatgaag cattaaattt aaaacaacta
    55681 caccaatagg aatagcaatt aatcctccta tacttccgta taatatactt tcaagcatca
    55741 atatacgagt tacagttttt tcattggcac caatacttct aaatgttcca ataaaaggaa
    55801 gacgttctaa tgtaataacc ttatagctgc tgtatatgat aaatatacta agggttaatg
    55861 caaaaaaact tattaaaaag aaaggcattg tcttttgtct agcatctgaa attatcttag
    55921 tttcatttat agtatttgat accatatatt tttcagtgga aagttcttcg gataatttat
    55981 ttactagatt ttctgtcatt tcttcttctg actctataag aactcttgta tatccactgc
    56041 ctttatttat aatttttgat agagtctctt tgggtagcag tgcatttaca cctcttgtat
    56101 tcctcaaaaa tactgtatca taagatgcaa tatcactaac ttgaaaagta taagactttc
    56161 cataaatctg taaagtaata gaatcacctt tttttatttt atattttgat gtaaagcgat
    56221 ttggaagaat aattttatca ccagaaaaat cagtaatact atcgccattt tctaatcgtg
    56281 gcttgttgat tttatttagt tgacttaagt ctgctgatat aagactaaat tcttcatagt
    56341 atcccccttt attataaata gcagagcttt ccaatacacc aacctttgat tttatagcat
    56401 ttaaatcagg tatgtcttct aaattggtta atacatctgg atttttactt tggacagata
    56461 tagtcgctgt accatacata ccttttgcca tttttctttg tgcactttca taagataatc
    56521 caattgagaa tgaaacaaaa agtaaaactg ttgataaaac tatggacagt aacataactg
    56581 ctgttctaat ttttcgttct ttaatatttg tgaaaatata ctttaatata attttcaaat
    56641 ttacaccttc ttcctttatc taagatattt cagtataata tttttatact ttaatccaaa
    56701 ttgaatctct aatagactcc tccatacttt tatcattcta tttataatat ttttaatcaa
    56761 atcacctcct taaataaaaa agattgataa actactatat aaatataata atctatcaac
    56821 cttaatatat tttttatttg accttaatta accttaatta aataggaaag gtgatataaa
    56881 atgagctacc taatccaggt atactttcaa cagatatatt ccctccatga acttcaataa
    56941 tttgcttcgt tattgctagt cctaaaccag ttccttctat tttttgtttt gtattgcttc
    57001 ctctataata acgattaaac aaatttgatg cttcttctct tgacatccct tttccattat
    57061 cagatataat gatttcaatt ctttcattta atgttatatg tacacaaact ttagtatttt
    57121 tatctccata tgtaaaagca ttgacaataa gattactaaa agctcgtttt aatagtgtac
    57181 aatcaaaatc aaagttaata ttatctatat tactcttaaa ttcaactata tttgattcat
    57241 attctggata atttaaaata tcaatggata attctttcaa gaatcttact aaatcatatt
    57301 tatttttatt taaaggaatt attccatttt ttaattgata ggttaatttt aaatcgttta
    57361 taagtgtatt tgtatattct atattcttta acatgattga agcatattta tatacttttt
    57421 caggtgaata attagtacta ctatctgtaa gaagctctgc ataccctttt attggtgaaa
    57481 gtggagtttt taaatcatga gttatatttg aaatccactc ttctctcata atatcagttt
    57541 tattttgtat ctcatcactt ctatgaattt cttcatttaa aatatttaaa ctattatata
    57601 tatcagcaaa aacaccttta atattaactg gaagatagct tcgttttgaa atatcactaa
    57661 cagcagatgt aatatttgat atgcactttg ttacccagta accataagca attccagaaa
    57721 tcaaaattat taaaaatata atccctatga ttgaaaatac aattgactta ccacctacaa
    57781 atttacttcc atcaaaaaac atattcactt tagatatatt taatggaaaa tatataatat
    57841 aaatatagtc atttttatta tttttaattg tattaaagta tacagttcca ttacttgaat
    57901 tattttggtt agctaatgtt aataattcag aattagaata ataatcttta tgctcttttg
    57961 gttctaaaaa cccataaact ctatttccac tagaatctaa aatttgcaac cacaattgat
    58021 tttctcgaag cttttctaat ccagactgtt ttacttgtgg cttattatct ataaatatga
    58081 tttgttcatt aaagttttct gtaaattttt tcggccagtc actacgaata aattccccat
    58141 ttggtttctg aatagtaata agtgataaga aaatacctat tactgtcagg attaagcaaa
    58201 taaaaatcat gaaaaaaata atgtatgaat gaaatactgt tttataacta ggtttatgca
    58261 tttaatcaac tcttttctta aacttttatt ttagtttgat tgttgcttat ataaaataga
    58321 taataattat tgatatgtaa aaatttattt aaaaatacaa ctatctacat aaattatatt
    58381 tatataatta tatgttatca agctgtctgt tgtatttaat aaatcctttt gataacatat
    58441 aaaagcaaga taattttttc cattaaatac cttataatta tacacaaaat ctctatatac
    58501 gttaaacagt atagagaaaa ttttcataga accatcttta taggggatac tttataaaag
    58561 aataaaaaaa ttataatata taaaaaactt cataggagtg taacaacatc agtaaagata
    58621 tgaaaacact atataaaaat tcaaaaatat taagaataat gaaatacttg aaattgctta
    58681 tatcaagaaa ttttatataa tataaactgg tcaaatatgt tataatatta aattgtgaca
    58741 agttcatgga ggtgtttata tgaaaaaaca aaagtcgcca attttacttg aaatgcttgg
    58801 actatttttg ggttgtatat caatgagtat tggtataaat atgtttttaa aaccacatac
    58861 aattgctcct ggaggactta gtggtctatc attagtacta aacaaggtta caggacttcc
    58921 agtatcagct atcatgttaa ttataggtgt cccattagta atacttgctt ttagaattat
    58981 gggtacaaaa aattcattaa aaactttatt tggaacagtt gtattttcag ctatagttca
    59041 attaacagac ccattatcaa aactaagatt tactaatgac ttattattgt cttctattgc
    59101 aggaggaatc ctagttggta taggtttagg aataatgttt aaatcagatg cttctactgg
    59161 aggaacagac ttaattgcac tcatacttag taagaaattc ccaggaataa aagctacaaa
    59221 attcatgtca tgcctagatg gaatggttgt tatatcttct ggtatagtaa atcgtagttt
    59281 agaaactgct ctttactctg gtatagcact ttgtgtatta ataaaaatag cagatatgat
    59341 aatggaagga tttgaccatt caaaagcatt ttttattatc tctgatgagc ctgaaagttt
    59401 aagacaagct ataactgaag aacttgatag aggtcttact attcttgatg gtaaaggtgg
    59461 atacactaga gaaaataaag aagttctatt agtcgtagtt tctaaaaaac aagaacttta
    59521 tctaaagaga ttagttaaaa gaactgaccc tactgcattt gttattgtta cagatgtgca
    59581 tgaggttctt ggagaaggat ttaaaaattt agagaactaa taaaaattaa tattttaagt
    59641 atatatacta ttttaattaa aatacgattt attcaaaaag agtgtctcat aaacttttta
    59701 gttcatgaga cactcttttt tgtataaaat caaatgcatt ttcagtattt taacaataaa
    59761 aaacaggatt atctatattt tgagtcaact actttattga aattttattt agaaaacaat
    59821 cattactaaa taaccaggat agatattaaa tgattatatc tattgttttt tcaattcata
    59881 ttgataacaa ggaacatttt ttacagtatt tccagtatga atttttttga tatactttcc
    59941 tgtacattta aatcctaata aatctaatga ttttgtagaa ttttggtttt cttcataggt
    60001 tattgcaatt attttattta agtttagttc tctaaatcca tactgtatta ctctttttgt
    60061 tatctcagta gcaaaatcat gtccccaata gcttggattt atacatatac ctatttctgc
    60121 ttctaatgct ttaggattta tattattaaa ccccatattc ccaataactt tattgtctct
    60181 tttatatact atagcaaagt ggccaatttt ccctttttta tagggattta gaaaaaatga
    60241 ttttataaac tttcttgtat cttctaaaga tttatgctca ctaaatggta aatgttttac
    60301 tactatttta tttttataac agtcaaaaaa atcttcaaca tcatctaatg atgcaggtct
    60361 tagtatacaa cttctagttt ctaaggtttt catttgagga tattcagaat cagacatttc
    60421 taatccccct ttatacatta atctaaatat actgttcata tttaaaatac gatattaatt
    60481 atataaatgt tctcaaatta accttatctt tatttttaat aaaaactaat tactatatga
    60541 atctttcaaa tttacgaatt tatctctatt tttatattaa attacttgtg aaatatgtat
    60601 tctaaattat atgttattag atatcatgct taaaaattct ttggttgcta aggataaaga
    60661 tatatctttt aaatggcagt aacctatatt tctcttaggt attggctctt ttatatctaa
    60721 tttaaacaat ttctcatttt ccaaataatc tatgctaaat tcttctataa cacaagacac
    60781 tccaagattt atatacgcaa attctaaaag taattcatga gaacccaatt ctatatccgg
    60841 gtttagtttt ataccttttg ataaaaaata ttcatttaca taaagtcttg aatttgcttt
    60901 attttctagc attattaaag gcaatgtgtt taattcttcc aatgatattt tcctaccttt
    60961 gtattctatg taatcatttg cacatacaaa tatatcatgt atttcaatac actcaacaat
    61021 atttagtgta tcatcttcta ttggcatgtt tataattgct atatctatat tcccatcttt
    61081 gagtaaagat ataagttctc tactcgttct atttattgta gatacatgta tatgtggata
    61141 cttcttatga aaaatttcta aatattttaa caagaaaaaa cgtgcagctg tatctcctac
    61201 tcctattttc agagaaccgt attctaattt tttaaattta tttattctat cttctcctga
    61261 tgatatcaac tttaatgcag tagtgacatg ttcacttaga attttcccct ctggagttaa
    61321 ttttactccc ttattgtttc tataaaataa taaagtatct aattgttctt ctaattgctt
    61381 tattgactgg cttacagctg gctgtgacat aaacaattcc ttagcagcaa gagaaaaact
    61441 cttattattt acaactgcat taaaaacctt ataaagttca agttttatat tcatatataa
    61501 ttactcctta tgtcaaatat tagtattatt tattttactt ataattatat ttgaattata
    61561 atatacatgg tactaatatg acaatattaa ttctttagga ggattttaga taatggatag
    61621 attagttgga actgtttcaa gaggggttag agcacctatt ataagacaag gagatgactt
    61681 agttaaaata gttgttgatt ctgttttaaa tgcgtcaaaa agtgaaaact ttgaagttag
    61741 ggacaaagat gtaattgccg ttacagaagc tgttgtagct agagcacagg gaaattatgc
    61801 tcacgttgac aatattgcaa aagatgtaaa agataaattt ggagatgata ctgttggggt
    61861 tatattccca attttaagta gaaatcgttt tgctatatgt ttaaaaggaa ttgcaaaagg
    61921 atgtagaaaa gtcgtattaa tgttaagcta cccttctgat gaagttggaa atcacttaat
    61981 aagtattgat gaacttgatg ataagggaat aaatccttgg tcagatgttt taacagaaga
    62041 aaaatacaga gaactatttg gatataacaa gcatacattt actggtgtag attatgttga
    62101 ttattataag aatttaatca aggattgtgg tgcagaggta gaaatagtat ttgcaaacaa
    62161 tccaaaaact attcttaact atacaacaag tattttaact tgtgatatac atacaagaca
    62221 aagaacaaag agaattttaa gacaaaatgg agctaaaaaa gtatattcac ttgatgatat
    62281 aatgacagca agtgtagatg gtagtggtta caatgaccag tatggacttt taggttcaaa
    62341 caaagctaca gaagaaacag taaaattatt ccctataaat tgcgatgaag ttgtaaacaa
    62401 aatccaaggt aatataaaag aaataacagg gaaagatgta gaagtaatgg tttatggaga
    62461 tggagctttt aaagaccctg taggtaaaat atgggaatta gctgacccag tagtatctcc
    62521 tgcttataca aaagggctag agggaactcc aaacgaagta aaattaaaat acttagcaga
    62581 taatgatttt gctgacttat ctggtgatga gttaaaagaa gcaatttcaa aatacatagt
    62641 tgaaaaagat aataaatctg atgatttaac aggaaacatg gtttctcaag gtactactcc
    62701 aagaagatta acagacctta taggttcttt agcagattta acatctggaa gtggagataa
    62761 gggtactcct attatttaca tacaaggata tttcgataac tatacaaaat agtatgtttt
    62821 aataagattt aatttttttg gattatatat attaacatga aaatttatta aaacctctta
    62881 atagatatga cttttcaaga gttatatcta ttaagaggtt tatttaatgt tcacagataa
    62941 gatatattta aataatttaa acaagattgt cataaagtta tataatctta aaaatttata
    63001 taactctaac tcttatttat ttctgaaata atatcactct tcaaaatttg tcttactgga
    63061 ataattacag caactatact aatagtgata tttaaaataa tcatacctat gtatagaggt
    63121 gtatttattt taagaattgg atttatatat aaatatacac gttttaccat aaaataaatc
    63181 ataaattgtc caataacact tccaattacc attataatac ttgcatagaa tccatataaa
    63241 aaaccttctc ttatcatcat aagtaaaaac ttattatccg taatacccat agctcttaaa
    63301 attccaaact catgtcttct tgaaaaaatt aagtagctta ctgtattgat tatatggaac
    63361 aaacttattg caagaagtac aaatacaata ccatatataa ataagagttt ttgatttaag
    63421 taggtattat ttttttcaat agcaatggta taatctgtta cgatacatct ttttacatca
    63481 cttacaacac tttttatgtt ctcagacaat tcctcactgt tactatcttc tgtctttttt
    63541 atacttactg aattataatt ttcgatatca aagttatttt tcatttgccc attcgtcata
    63601 actatatcca taccataatc accaatgaaa tatatgttat ttgccatcac acgttttaca
    63661 gtagcagcaa ctacaaattc ttttgttgta taatcattct tattttcttc tttaaattta
    63721 acaatttcac ctgttggttt cattgtcttt ggcactttaa cttttattgt atctcctgga
    63781 tttatatcaa ctgcatcata catcccagtt ccatccatag gtagtctaac tataacctta
    63841 ttatttttaa ccatatcatg ggtattaatc tccccatcta taatataaga atttaatcct
    63901 tctaacatac cattgttata accataaata tttgttttta aaagatagcc accttcattt
    63961 tgctttgtac aaataccatc aaaaaaagtc tttatcctgt aatctttttc aagaggttta
    64021 aagaaatttt tccaaaatag ttgttcttct ttaatttgca tagctccaaa taaatatctt
    64081 actggataga cttttgatat tccctcaaca ttgtttaatc ttgaaatttt atcttttggt
    64141 atacctacat caaaatctgt tgtttgcata gttatttggt agtcagaatt taaaccatca
    64201 tcagctttca ttgtaagttc attattgttt ttagtaagct gtatagagta actagaacat
    64261 agaaatataa ttccaccaag tgataatgaa aacaaaattc caataaacat tccccttttt
    64321 tgagtcatgt atttatgaga taatactttt gtcatgttag agtgttttac actttctaat
    64381 attctctttt tcttattagt aatcttaaag tttttcatag attctatact agagtattta
    64441 ttcaactgat gtacaacacg tacagcaatt aaaattaaca acaataagat aaataaaaag
    64501 cctaaataaa tagatttttc acttataaaa aatgctcctg gaacaatatc actactcaaa
    64561 aatatatgtg gaaattgttc atatattgta gacgctactc caatacctaa gaagcaacct
    64621 ataggaaatc caacaataaa aagtaaaaat aactctaaaa atagtagaaa taaaagttgt
    64681 ttattattag cgcctaatac ttctaaaacc ccatattgtg atattctctg aagtattgaa
    64741 acatggaaaa tactatatac tgctgctgca ccaaacactc caacaagcaa tataattgca
    64801 tttgtattta gttctaaatt ttttaagaac tcaaatatat tatatttttc tatattcttt
    64861 ggtggtttta ctccaaattc aactgaaaga ggccagttta tataagtttt ttcttttgat
    64921 atgttgaatt ttttcataaa tttataattt tgctttttaa tatttttatt ttcatcatat
    64981 tttacataaa ctatataaga atccttttct ttaggctgca aataatcgtt tacaaatccc
    65041 tccatagcag tttctgggtt tgaaagactt gataaaatac cacataactt atagatttta
    65101 ccatctaaat tgatttctgt tccaatttct ttgtttacat ttaaattgtt tagagaatat
    65161 gtgtcaagta ctatctctcc atctttacta ggaagagttc cttttaataa ttttctacct
    65221 gtcatgtcta aatatgaaga atcagcattt aaaaattcta taataaaagg ttcatctatc
    65281 tgatttttag gttttgtaac gccaagtcta tctacaatgt attcctttga ttttttattt
    65341 tttttaattt tattaagttg ttccttatct actttataga aataatgata atctccacta
    65401 tcttccctta tcttttcaat tctacttttg tctgcactat gaactaaaga accaattccc
    65461 gtcaataatg ctactgatag tactatgctt aaaactatag atatagattg ttttttataa
    65521 tgctttatat attgaattga aaattttact agagacatca tagtacttca ccaccagtat
    65581 tcaccacaac tccatcttca atatggataa ttgagtcgca tacttgtgct atattttcat
    65641 tgtgtgttac cataagtatc gtttgatgga attttgcact actttctttt aataaacata
    65701 ccacttccat tgtagtttta ctatcgagat ttcctgttgg ttcatctgct aatataagtg
    65761 caggtttatt tgccaaagct ctagcaattg ctaccctctg ttgttgacca ccagatagtt
    65821 cgcttggaaa ttttaaacgc ttatcccaaa ttcccaatgt cttcatcagc atttcaatat
    65881 attcatggtc tatatggttt cctttatcta atgtaacagg aagagctata ttatcataag
    65941 tgtttaatac gggcattaaa ctgtagtttt gaaatataaa tcctatattt cttcttctaa
    66001 atactgtcaa atcttttttt cctattttag atatgttctt tcctttaatt attacatcac
    66061 ctgaggttgg attatctaat ccacctataa tatttaacaa tgtgcttttt ccagaaccag
    66121 aagttccaac tatagcagta aatgtatctc gttcaatttc tatacttact ccatttaagg
    66181 cttttacttt agtctcacct tttccatagt gtttcactaa attattcgtc actaatatac
    66241 tcatttaatt tctcctttca atacagatat atgttctata aaatattgta agtgacgata
    66301 attacactca tcctacaaag ttagtttaaa ctcttacaat tctgtaagaa tatactaaaa
    66361 caacatccac ttcctagttt agattctact ataatgtttc cattttcttt ttctaaaatt
    66421 aatcttgtaa gatatagacc aatccctgtg ccattttggt tttccacatt tttacttctg
    66481 taaaatcttt taaaaatatc atttagttct ctactatcaa tacctattcc ttcatcttta
    66541 atagtaatct tcgtatatag ctccattttt attacagaaa tagtaatcgt gctatctgat
    66601 ggtgagtatt ttattgcatt ttctaaaaca tttacaattg cttctatggt ccacttttta
    66661 ttatgaacta actttatatc tgaaaatggt tcgagattta tccttatatt tttagcttct
    66721 gatttattaa agatagtact gatgctttga ataagagtat ctttaattag tagttcttct
    66781 acttcaaatt ctataactcc atcctctaat ttagtcattt taaataagga ttgtaacaac
    66841 cagtcaatct taaaagtttc atttttcatc ttttgtaaaa actccttctt ctgtaatgtg
    66901 gaaatattta tattctccag aagttcacaa taaatggtta tatttgaaag tggagttttt
    66961 aattgatgtg acatatttga tattaaacct ttaatcgctt ctttttctga ctttgactgt
    67021 tctacctcta tttctatcat atccttaatt ttttttactt ggtgagaaat ttttgacgct
    67081 cttgtatcct tcgtatctgg ataagtaact tctttacctt ccaatatttg atttaacatc
    67141 aaatttaatt catcatatct tctttgattt attttagtag atactataaa tataacaact
    67201 gtacatatta taaaggctaa tataaacata ttattctacc tcattccata aataacccat
    67261 tccataagct gtttttatat attttggatt agatgggtca tcctctactt ttactctaag
    67321 tcttcttata tttacagata caatattatc atcaacataa ttttcttcgc tgtcccaaat
    67381 atggtgtaaa atttgttcct ttaataatat ctgaccttta ttttcaatta gataacttag
    67441 aagcttatat tctacagagc taagttccaa acatgcttta tttttatata cttttagtaa
    67501 cttttggtcc aattttattc cattggaata tattacttta ttattcgatt tttttcttat
    67561 tgctactttg actcttgcct ttaatacaga taaagaaaat ggttttgtaa tataatcatc
    67621 aagccctatt tctaatcctt ttacttcatc aatttctgag tctcttgcag taagcattat
    67681 aattggtata tctgactttt cccttattat ttgacataca tcaaatccat ctccatctgg
    67741 aagattgcag tctaagatta taaaatctat atttttacta ttaaatatat ttaatccttc
    67801 ttgttttgta taagccttaa atacattaaa tccatcattc tcaaatgcat aaaaaagacc
    67861 ttcatttaag tttatatcat cttcaataat taataagttc aattttactc tcctttagat
    67921 tttttagata aataattatt ttcttgcatt atcatactaa aaatatttta attttattta
    67981 tttcactaaa aagattgtat ttaaatttgt tttcaaaata aaaacatcat aatcaagcat
    68041 atagttatat atttcccaat ttaattacgc ttaaattgaa aatataacgt tattcttata
    68101 taattaaatt atacaacaat aaagttatat tttttaaata tatttttact agggggaata
    68161 gaattgaaaa gggttgatga gagaaatact atgtttgcaa gagcaaatta caaaaaagat
    68221 agtactgctt ataatgatta ttataagaaa aatcctgaca aaaaagaaat tgatgatagt
    68281 ataagaaata gaccaaattt atgtagtgaa ggaacaatga cttacaatga gttaaactct
    68341 ccaatggcaa gtagtgcatt cgatttttta tctgatatca aatctttatg cgaaggaaaa
    68401 gtttctgata ctaaagtaga tgtagatgca aagtcaatga caaaaaaaat taagggtctt
    68461 gcaaagcagt atggagcttc tgtagttggt ataactaaat taaaagacta tcatatttat
    68521 acaaataggg gtagacatga agaaaattac ggtgaagaaa ttaatctaac tcataagtat
    68581 gcaattgtat ttggatgtga gatggataaa gaaatgataa atagagctcc aatgatatgt
    68641 gaagttatag aaacatcaaa gtgctatgtg gatgcatcta tcgtcggcat gattttaagt
    68701 tactatataa gaaatttagg atatgatgct agaaatcata tggatgctaa ttatttagta
    68761 atgcctgttt ttatagctcg tgatgcaggt ttaggagata taggaagaaa tgctatactt
    68821 acaaataaag attatggctc tagacttaga ttaggtgttg ttactacaga tattcctctt
    68881 ttagaagatg aatatgttga ttttggacta gaagattttt gtaaggtctg taaaaaatgc
    68941 tcttttaact gcccttctca ttcgctttct aatgatatta aaattggtga tgatggaaaa
    69001 tataattggg taattgaaca tgagacatgc tatattaaat ggagatattt aggtacagat
    69061 tgtggtatgt gtatatctgc ttgcccattt agccaaaatc tcgaaactat aaagaatact
    69121 acttcattta agggtaataa tgagcttatt caaaaagctt tagatgagta tacttcaaaa
    69181 tttggtaaaa gaatatttat acctggaaat ccatcttggt tgaaataatt ttatttaata
    69241 aagaatctgt actagaattt atcataggac aggttcttta ttaaatatat aaatttttaa
    69301 atactttttc tcgtttataa caattcagca atgtttttag tctataattg acattataaa
    69361 atattaaact aaaaggagta actgtatgga aaaaatatta gtagtagaag atgattctat
    69421 attaaataaa actctatcat ataacctaat tgaagatgga tatataatta cttcaaaatt
    69481 tacagctaaa tctgcactaa agtctatttt tgaatgtgaa tttgatttaa taattttgga
    69541 tattaattta ccagataaaa gtgggtttga attatgtaat gaaataaagg aaaattacaa
    69601 tataccaata atttttttaa ctgctaatga tatggaatgt gatatgatta aaggctatga
    69661 acttggagct ttggattata taacaaaacc atttaatatc aatttattta aacagaaagt
    69721 taaagctttt ttaaatcatc ttacaacaaa aacaaaacaa gattactata gggatggata
    69781 tcttgaaatt aacttttctg agttatctgc caatataaat ggaaatcaaa ttatatttac
    69841 accattagaa tatcgtactt taaaactgct tactgaaaat cctaaaagta ttttaacaag
    69901 gaaagtactt ttagaaaaac tctgggatat agatgctaac tttgtagatg aacatacttt
    69961 aacatctgtt ataagtagga ttagaagcaa aattgaaaaa gacaatctta agtatatcaa
    70021 aacggtatat ggtatgggat atatgtggtt aggtgaaaga aatgaatttt aaaaaatttt
    70081 cttttagttc tatttattta ataattgctg ttggtataat ttttacagct attttattta
    70141 atatttcaat ttatctaata actgatgatt taaaactaat tgctctatta ttaatatata
    70201 caatagtact ttgtggattt atagcattaa taatattttt acttcataaa aaaatagtta
    70261 tattttgttc taaaatatgt cacactttag atagtatgat gaatagtgaa gacaatattg
    70321 aaattgaatt agaagaagaa actattttat cacgtatcaa tcacagatta attagaatgt
    70381 atgaagttat tcaagaaaat cgcaatagta ttgctataga gaaagctgat ttacaagaac
    70441 tagtttctga tctatctcat caaattaaaa ctcctattgc aaatttaaaa atgattaata
    70501 ctactctact aaatcaaaca tttaaaacag aaattcaaaa ggatttttta atggatatgg
    70561 aaaaccaatt agataaatta gattttttaa tgcaatctat ggtaaaaacc tccagactag
    70621 agacaggtat aatcacacta tctaaaaaga aaaattcaat ttatgaaaca attgctacag
    70681 cacttagtgg aattttgttt gatgctgaaa aaaagaatat tgaagttaca gttgattgtg
    70741 acccaaattt atatataatt catgacaaga aatggacttc tgaagctatt tttaatatat
    70801 tagataatgc tgtaaaatac acaaattcta atggtaagat acgtgtagct acagaatgtt
    70861 gggttatgta tacaaaaata gatattattg ataatggaaa aggaatatca gaaagtcatc
    70921 aagcagaaat ctttaaaaga ttttatcgtg aagaagatgt acatgacata gaaggtattg
    70981 gaataggtct atatctttca agaaaaatta tatctcttca aggtggctat attaaagtta
    71041 catcagatat tggaaaaggg tcgacttttt ctatcttctt acctaataaa taaattttta
    71101 aatattttat ttgtaatgat tctgcaacat tttgatttta tactgtattt acaagatgtt
    71161 aaggaggtat tattatgagt attttacaag taattaattt aaagaaatat tatggacaaa
    71221 gttcaaacat tacaaaagct cttgatggtg taactctatc tattgaaaaa ggcgaattta
    71281 tttctattgt aggtacatct ggtagtggca aatccacatt attaaatatg atgggaggat
    71341 tagataatcc tacatctgga aaggttatta taaagggtaa ggaattatct actatgactg
    71401 atgaacagct tacaatcttt agacgcagaa atataggttt tatatttcaa aattataatc
    71461 ttgttccttt acttaatgta tatgaaaata ttatcttacc aataggattg gatggagaga
    71521 ccatagataa ggattttata aatgaaatta taaatatgct ttctcttgaa gaaaaattat
    71581 atgatatgcc aagtaatctt tctggtggtc aacagcaacg tgttgctata gctagagcac
    71641 ttgtaacaaa accagctatt atactagctg atgaacccac aggtagcctt gatagtagaa
    71701 ctagttcaga tgtactgagt ttacttaaag tgacaagtaa aaaattcaac caaacaattg
    71761 taatgattac acacaataat gaaattgcac aactaactga tagaattatt cgtattgaag
    71821 atggaaaaat tgttaactag gaggtgtagt atatgtttag aaataataat cgcacattta
    71881 taagaaaaat agctttaaat gatttaaaaa ttaataaact taaaacatat ctttcaggta
    71941 tcattataat gatttctaca tgtttattat taacagtgac cttagtttca tataatgctt
    72001 ctgtagattt agttaatgca tctccatatc atgctatata taaatctgta gatgaaaaag
    72061 caaaaaatat actatataaa gataaaaacc ttagtggcgt aggaacctac aaattaattg
    72121 gaagtaataa aaagacagac tgtattatgt cgattgttta tgcagatgat acagcaatta
    72181 aacttatgaa ttttcaacca ttgaaaggca aactacctac aaataaaaat gaaattgcta
    72241 tttcagaaaa atatttacag gaatttggtt tagataaaga tattggagat agcattaaat
    72301 taaattatta tgatgatatt acgaataaag aagttcaatg tgattttatt attgttggat
    72361 ttctagaaaa ttattatcaa gataatgcca agcaatacta tacagtcgtt tcaaatgatt
    72421 attttaagaa tatagcttct acacctttac aaaataaaag taatactttt gacgagtcaa
    72481 gacctgatac tgtagatgta ttagttaaac tatcagaaga aaatacagag aaagattcag
    72541 cttcaattaa gacacagtta aagaaaattg gtttatcttt aggtattaag aaatataata
    72601 tatacttaaa tgataactat attgaatcaa atttaattga tggtgagcag attattacag
    72661 ttttagtagt tggaatagtt gttctttttt ctagcgtttt tgttatatat agtatttttt
    72721 atatttcagt tgttaattca gttcagatgt atgctaagtt gaaatcgtta ggtatgactt
    72781 cttttcagtt aaaaaagact atttctctac aaggaaatat tttgtcaatt atttttattc
    72841 cattaggggc tatagcttct tgtataattg cttacataat tcaaccatta gcatggcaaa
    72901 tgatagctga tttatttata attttaattt tatcactggt aatgttttta actgttagaa
    72961 tttctttatt taaaccagct agaattattt ctaaaatatc tgctattgaa gccatgcaat
    73021 atacagaaac taaatttaga aaacaagcaa aaaattttag ttatataaat ataaaaaatc
    73081 tagcattaaa gaatatcgag tcaaatagaa agaaaaattt gattgcatta atatcgctaa
    73141 gcattagtgg agttttattt atttcaatcg ctaatcttgc taattcaata gatttcaaaa
    73201 aacaactatc tcaacaattt gtctataacg aagattatat aattagcatt aagagtgata
    73261 acttatatga gcatattaca gaaatccaac aaaataatcc actaacagat tctcttaaga
    73321 atgaaattaa atctattcat ggagtaaaaa aattaattga atccaaatca attaaaagta
    73381 atattataga accttacatc aaagatagag acgaaaaaca atttattact ctaattaaag
    73441 gtattacgcc tgaactttca aaatcacttg aagaatatat tgtcagtgga aaaatagact
    73501 atacacattt agattcagat agtttaatta taaataaata tagaacaaaa tcttatggat
    73561 taaatttaaa agttggagat acagttacat ttaatatctt tagtggaaat gatattatta
    73621 aaaagaaaat gaaaattata ggaatcattg acaattccaa tacaggaggt atgttttttg
    73681 cttcagacaa aactttagaa tctctaacac catataatac aaatttagat ttttctattt
    73741 taatagataa aaagcattct aaagaagttg aagaaaagtt gttaagtata attcagaaaa
    73801 attcaaattt aatgctttat tcatatgaag atgattatag aatgattact agagcatttc
    73861 aatatataat tatagcttca tacatttttg ttggtttaat ttcttgcttt ggtatactaa
    73921 atatgaccaa taccctaata aacagcgttt taattagaaa aaaagagttt gccttacttc
    73981 aagccgttgg aatgacaaga aagcaactgc gaaatatgct ttatagagaa ggtctaaaca
    74041 taagtatcaa agctatatgt acttcaagta tactaggtta ttttggttca aatctacttt
    74101 gcacttttat aaaagatgta attagattag actttattaa ttttaaattt tctatattta
    74161 ctattttaat tttttcattc gtattaattg gtatacaagt tttagtgact gaattactta
    74221 taagaaatat agaaaaaaaa tcacttacag aacgcttacg ttctcagtaa gaatgtatat
    74281 aaaaaataac cattttttat acaagtttta acataatttt ttaaaagcta aaaggataga
    74341 aaattttgac tttacataat tttctgtccc tctacttgtt tttattttat acagatacac
    74401 ttccttatat ctccaagcaa catcaccaga gacataaaca agcatattcc ttattttcta
    74461 aatatgtcaa ttgcatgact tgtaactcct actaaatctt cacgttcaca agtagcaagg
    74521 tgatatttta aatataacgc aaatgcatca tcatccatag agtctactgc ttcacgcata
    74581 tacaaagcca aaccatctga tgcgacataa tgcagtctag ttacattaaa tgcagacatc
    74641 aaatcatcaa tgttttcttt acgtacaagc tcaaacaaat cctttggttc agacttagca
    74701 gcaaatgtct gtggatcaat caaacctttt tcaatatatt cagatacatt aatatttcct
    74761 ctatggaacc cctcgtcaat gagacagcca tcagatataa cgtatgcagc aaaaaccaca
    74821 ccaccaggtt ttgttacacg aattgcctca tgtaaagctt gttgtttatc ttctttgtta
    74881 taaagatgat atagtggtcc taacagtaac gtaatatcat atttattatc tgggaaaaca
    74941 gataaatcca tagcattacc ctgagtaatg cttatatttt catttgattg agtattttta
    75001 tggaaaacct ctatattatg ttcgactaat tccactgcgt caacatcata tccctgacgt
    75061 gccagtgtgt gagaataacg accagttgca gcgccaattt caagcacaca atcacctgat
    75121 tttatgtact tatcaatgta atgcatagta gtgagaaatt ccaccattcc atgttttaat
    75181 gcaagtcgac tatcttcatc ataagtatta taaaagtcaa ttaagtattg ttttgtttcc
    75241 ataatctcac ctcttctata ttagttaata aacatcaaat agacaaattc caatctggtt
    75301 tttcttgtct tataaaagct gttaatatat ttttcaacat tttttcagca ctatatctat
    75361 ctaatgttaa tttttttgtt gctgttaaga cagctatgcc atgagtataa agaaataaat
    75421 ctaaaaatat tacttttgca cattccaact ctattccaat gctttccgaa aaaagtcttg
    75481 cctttttttc attgtcaatt tctttataaa aatcattcgc ctctttcatc atcaaatcta
    75541 aatcatttat aaataacaac ttaaataaat acgtttcttc ttgagcaaat tcaatgtatg
    75601 aaagcggaag cagtaaataa gggcttacac ttttagaatt acgataatta acaacatact
    75661 gattataata ttcatatgca aaagcaagaa attcattttt taattcattc atgttttcgt
    75721 aacaagtaaa aattggtcga gtggaacact gtaatttact tgcaatactc ctcgcattta
    75781 cagcttcaaa tcccacttct cttgtaatat ccaagactgt attcaaaatc atttcttttg
    75841 ttatctttac tttaggtggc atatatgttc acctctccat taaattttta taaaacacat
    75901 atgttatata actatagtaa catatcaaga aattatgtca agaaaaagct ttgcattttt
    75961 ttgcaattcc taaaacttat aaataaaaca tgagttgcaa ttaatctatt aatagataac
    76021 agcaactcat attttccttt aaatactctt ctttttgtct aatatttcat atacacaatc
    76081 ttctattgaa ttaatatctt tttcttttct ttttttagaa tcaattaaaa tgaaatacag
    76141 tataaaacct acagcaagtc cccatgttcc gcctttagca gcaattacac ctcccataag
    76201 tccaatcaat cccttctcaa cacctgtatt acatagctcc attgatagct ttgtacataa
    76261 atatccttga actaaaagtg ttactgacaa tgctaatggt ataagaggtg tagcaatctg
    76321 cgcaattgga taaaaacaga taaaaattgc tgaaacccat actaatgtac ccatgccact
    76381 aaaaacagac tgcatggctt cctttccaac cttgtacctt tgagcaacac ttcctgtaag
    76441 tgtcgcagct aatggaccgc acattggtat atatggagaa aagattgcca taaaaatatt
    76501 tcttatccca cttataacat tagacctatt tgaattgaaa tctatatatt catcttttct
    76561 attttcactt tcagaaagta ctaagttttc acctgttata aaatcaccaa aggcaattat
    76621 gtatatcata aaagccattg gtatcccttg tataaataac attacacttg gaaaacctat
    76681 tccaaaagga gatactgtat ttatcagatt tttaaaatct actatgtaaa ctaaattgtc
    76741 aaaactaaat ctaggaattt ctatttcttt actaaatata cctactatta aactcactaa
    76801 aatagctgat actacaccat attctcctaa atgaaataaa aatttattct taacttttag
    76861 agtatcaaat ctttcagaaa acattacaaa acaagcaacc aaaattccta ctgttataga
    76921 tataggataa gaatcaaatc tccctttagg attaaactct gatattatag tcgatatacc
    76981 gacacccatt agtattccac ctttaataga atttggtatc ttactaacta actttccagc
    77041 tacaccagtt atacccatta aaataaatat tattcctaaa tctatttgta aagctgttaa
    77101 tgcttgtatt ctttcaatgc ccatgctgaa ctttaacaaa tatgcagttg taagagttat
    77161 agaagctgta atccagccag gtacaactgg gtctcccata aaaacatgca aacagtataa
    77221 tattgagtta ataatagcca tactccatgc cacttcatag ggtaatccca aaatttgtgt
    77281 actaaggcca attgtgccta aacttgtcat acttgatatt ataccttgaa tagcttctgg
    77341 tttctcaaat ctgtaatgta taaatggaat tcttatctta aacattccaa attttatatg
    77401 aggttgttcc cttctagcga gtctttccat aacttcactc cacctttcaa taactcttat
    77461 aagtttacaa ctttataatt gtttataaat tgtcaatgtc attaaaatta gtatataaca
    77521 tgcaaattat ataaacaata aattaaatct ataaaattga tagattttgt gcatatatag
    77581 aaaaaccgct tcatttttag ttacttaaat cacttaatat tagttattta aatcacttga
    77641 taaaagtttt ttataaaatt caatagttct attccatgat tcaaactgtc cttttgaatt
    77701 tccttctaca gttccacctg aagaaaaaat ccctccactc atactcatac ataaagtctc
    77761 ctttagaggc ataatatatg gaattggtaa cggatgaccc atattattgt atgttaataa
    77821 ttctacgtta tatggataat tattttcttc aaagatttct aatgcctcta aacaagcttc
    77881 ataactattc catatgttat cttcttttcc agcaatcata agtatatctg ctttggaatt
    77941 ttctattttt attctagcct cttttctatt ctctgctctt ttaagacttt tcttataagt
    78001 actattaaat ccaaatggaa taccttttga tatatttttt ttctgttctt caaagaatat
    78061 atcattgtct actttgatat atggaaatgg ctctccttta tatgaccatg atgaagtatc
    78121 atttccactc atcaatccat taagagcttg gaaacaataa atgtgaggtt gtgatactac
    78181 aaccttttta atttgttcat atcttgaagc aagtaaaaag gccaattctc caccctttga
    78241 tgtcccatgt acaaatattt ctttagtact ggtaatttca ttttcactaa tccactcaaa
    78301 tactttttca aaatattcta atggaacctc ttctaattta tctggtaacc cttctaaagc
    78361 aaagtatgca actgttagta cattgaatcc tctagatgca agtggagctg ctaaaaggtc
    78421 tagagcgtct aaatttccat cagaaccacc tagcattaaa attgttttat tattagaatt
    78481 ttgtttataa aataattttc ctataaactc atcagatatg tattttgtgg taatatcttc
    78541 tgatttaaat attctcttta attcaacttc ttttctttca gtagaagttt caaatatcat
    78601 attcataatt attggtttat caatagatat attttctgca aaatttttac cttcagtttt
    78661 agatttttcc agcgaataaa ttaaccccat acaattatca gccttataag taccttctat
    78721 aggttcaact aaatctaaat ctacttctcc tttttcattt gaacaaaaca ctccataaga
    78781 tgaaaattct tctcccttgc accatggaaa ttccattttc acacttattt taagtttagt
    78841 atttggaatt aagtctgaaa ccataatctt aagtctttca tccacaaatg attctacatt
    78901 gtatacattt actttcataa tctatttctc cttataataa ttatttatgc tttatatata
    78961 aaacaacttt atctaataca acataaataa atttttaaat taagacacca tattgactat
    79021 ttcattttat caacatattt catttttgtc aatatattgt cttttttagt aatttaaaat
    79081 tatgtagtct atatgaaatc cagttgattt ttggctaatt aaagatagga atgctattag
    79141 gtttaaaata tatctattca aaataaaaaa ccactcattt taagaatggt ttttaatata
    79201 aactatttgt tattaataag gatatttttt tatttaaatt tatataattg aacatctaat
    79261 atttaatgtt taataaaatt atgcatttgc aaaagtatat atggcattaa ctcttgctac
    79321 atataaattc tcatcactac atccaatata tctagcatat ttttcaatct tttcttttgc
    79381 attttcaaca tcattttcat cgctctccat taactcattt atataaatat ccattaatga
    79441 cgctttatat tcttttatat catagcctaa aaattcagtc aatctctcaa tttccttact
    79501 aaaatctcca tcttctttta ccaaaaattc gtatacatct tccctatatg gatttaaagt
    79561 tattatttgt tttactactt tgcattcgtc agccttccca ataaaaccat ctttataatt
    79621 attaaataag gcattagatt tttttataga ttcttcatca atataagaat gtaccgcagt
    79681 tatacgattt tctataaggg catctacaac agcataatga attttaaaac aatcattgta
    79741 taaataattg ctcattttct ttattgtcga ttctatttct aagaagctag cgtgcccatt
    79801 ttttttattt ttatttggta taataaaagt tttattcaag ttattaaaaa gtctcttaaa
    79861 atctaaatat ttttcacaat aaacgctttt aaaggtatcg atatctatag ttataattcc
    79921 aaaacttact atagtctcaa ttcctttctt aaaagactct tctatatatt tttctcctaa
    79981 acttaaacct ctatcagata tttgctttag attttgaaaa ctatttaaac aatctctctc
    80041 aaagttttta gatatttcta aagcatataa tttaaagatt ttccttatct tattataatt
    80101 attttttgta tcatcaaatc tgataatagc tccatttaca tcaaaagtaa tcattgagtt
    80161 ttaacctccc cattagtttc atcaataaaa taaatttaat ataaacttta taatcataat
    80221 attaaactta tttatactat aattattaat ttgatgataa aagctatttt ccttctaaat
    80281 aaaaaatttg tctaaagttt ctaaaaaatt tagacaaatc ttaggttatt attctttaaa
    80341 ttatttttaa attattccaa atacaccaaa taatattggt ataaatatag ctggtaacaa
    80401 attagctact tttatattcg ttaatttaag tacatttaga ccaagtccta taattaataa
    80461 acttccagct gctgtcattt ctgtgactac aggatcactt aaaaatccat ttaaaaatga
    80521 tgctcccaca catataatac cttcatacaa aaatacagat attgcagaaa acattacacc
    80581 tatacctaaa gaagcagtaa atataattga agctattcca tctataacag attttacaaa
    80641 taaagtatca tgacttcctg taagaccact ttctaatgaa ccaactactg ccatggctcc
    80701 tatacagaat aataaactag atgatataaa accctctgct atagaatctt ttttatttcc
    80761 tttagaaaat ttactttgta aaaaagcacc caacttattt acccatttgt caatatctat
    80821 taattctcct atcagagcac ctacagctac ggatattatt gtcactaatg tgttttttcc
    80881 ttctagtgct cctgatatac caatgtacaa tacacataag gcaattccat tcattatagt
    80941 atcacttact ctttgaggta atcctccttt tattataaga cctactatac atccacctgc
    81001 aattgctaga ctatttgcta ttactccaaa cattttttct cccctcgatt agctaattga
    81061 aatttatcct attattaaaa cctaagcatc tatactttgt attggatatt ttaaatattc
    81121 caaaaattct tcaaaacctt ttctagatat atttacagtt ttagtattta tgttaggatg
    81181 aaaatttaag taatcttctt taattacatc tttatctatg taaagctcaa cttttctttc
    81241 tgtatcattt attaatgaaa aaggatttac acttccagga agaagtttaa gtacattgta
    81301 tagtctttca ggtgaagcaa acgataatct agaacttcct atcttatctt taagtgagtt
    81361 taaatcaact tgtttttctc ctttaactac aataagataa tacttatttc ctttggcatt
    81421 tcttaaaaat aaatttttac attgacaccc ctttgttatt ccatctaaaa tgactaattg
    81481 ctctgctgta tatacagctt catgctctac tacatcatat tcaacattta atttatccaa
    81541 aatatcatat attttagttt cattcatgct agattcattt tcatcttgtt cttttttatt
    81601 atttaaatca ctcatacttt tctccttaaa cacttcatca taatatcatt gtgaggtatt
    81661 attctactat agctattgct cttactggag ctccatcagc atcattatac ttaaatggtg
    81721 ctgctataaa tagaaatttt tctggaacat tttctaaatt tgtaagattt tctatgatta
    81781 tttttccttt ttcaaataaa atatgatgca cttcaaatac tgatgtgtta tatctatcca
    81841 ctgatagcat atctattcct atgcctttta tattagtatt agctatatag tttgcagctt
    81901 cttttgttaa tgtaggataa cctacatagt actgcttttt atcccaaaat tttgaccaac
    81961 ctgatttaaa tattataaaa tcactatttt ttatttcatc ttcatatttt tttagatatt
    82021 ctaattctat attctcattt cccttttcaa gttccaatac ataagctttc ccaacaaaat
    82081 tttctatatc caacttatct agggtctcac ctttagtata catatgtctt ggtgaatcca
    82141 tatgagttcc attgtgagaa aatacactaa ttaatgtttc ttgataacca ttttcttcaa
    82201 taatagctac tttcttgata tctggtctat taggctctgc atatacaggc atgtcattat
    82261 gtgtcacatg agttaaatca aaaaccttca tctttatata ccccctatgt ttttattttc
    82321 tattatatac ctaaattcat tttatttcta tcagatttta ttccattata taccatacta
    82381 ctatatattt tttataaacc tcaagggatt taccgaaaaa tcttggaaag aattatcagt
    82441 aaatataaca tcttcaccca aaaaacgttt ataccttcct tcttctttct ttaaagtaat
    82501 tctctgtttt tgtgaatgat tattaaaaac cattatctta agaggaggtt tttttctatt
    82561 agtctgcact ctttttaaca tgtattttat gtgcatatca gcttcaggaa atgaatatcc
    82621 acaaaatatt aaaaggtcag tatctcttaa agttttttct gtttcattcc aaacattact
    82681 taaaaatatg tttgacatat tcttaaaata tgttggtggc actataatag gttctgttaa
    82741 ctcaccacac tctaaacatt ttgtctctga actattttca ataagcttca tgacaccacc
    82801 ttcatgtggt gtaagagtta cactattaca aatggggcaa taaagccaat tcaatgaccc
    82861 atgtatctta tataatttga ttaatggttc ttttggtttt ctccaattta actcctcttt
    82921 aaaatttgta aactccacac cataatcaag cataattggc aaatcattct tatctcttaa
    82981 tccagtaact gtattgtcta tatgtatatc ataatttgca ctaataaaag tagtatcaag
    83041 aagcaaatca ttttccaaaa gattttcaac taaaagttta tgatatttat tatctgttct
    83101 aggtgtatta tgaattgctt cagccattag cagtattaaa tattgtctta aaaaacgtat
    83161 actatcactt ctgttattta gattttctag tccaaaattt ctaaatgctt cttttctttg
    83221 ttctgctaag tctaaaagac ctaaaacttc ttcaaaggta ggaaaatttg cattatctat
    83281 attatctttt actatatcaa tattgaacat ctgtttaaag aaaatataca attctctatt
    83341 cattttggta ttataatttg tgggatttag ttttttaaaa tattcgctaa aaagttcatt
    83401 ttgaataggt agattctctg ctgctgaagc tcctgctcct aaaaatattg ctattttcat
    83461 atagttcctc ctaatataaa tattactcct atttttatat ccattaaata tccatatcat
    83521 ttattttatg atacaacaat aaagctgtct tttactagaa aaaatcctat tacaagacag
    83581 ccttatatta tattaaatct ttaataattc gtaaatagaa agagcatata tttgagtagc
    83641 ttttataata tcctctacta ttaagtattc attagcttgg tgttctgttt ctggttttcc
    83701 tggaaaaata gctccaaatg caacacaatt atctaaagct cttgcgtatg ttgctcctcc
    83761 agatgaaagt ggtgttccat caagaccagt ttcttcttca tatacttttc taagtgtctt
    83821 aacaagaaga gtatcttctg gaacatagat tgaatccaag aaatcatatt cttcataatt
    83881 taaattgtat ttatctgtca ttttctttaa ctcttttaca aaatcatcct ttttgtatgt
    83941 tactggaatc cttacatcta ttcctgcaaa ttctttttcg ttatcaatag ttactctacc
    84001 tatatttact gttagtttac ctgatacatc atccttgcaa ttaggaatta tattgtttcc
    84061 attagcatct tcaccaataa cttctgctaa aaacttaatt atattagaat ctatacctat
    84121 attattaaga gctatacaaa gtctagccac tgcatttata ccagtatcac ttgctgctga
    84181 atggacactt tttccaatta tacagatttt attaccttca acagtatact caaaatttaa
    84241 tttatcaagt tcttttttta atttatcaga gtattttcca atatagattg ctttacctgg
    84301 aactgcattt aaagcctttc caactgacaa ctctatatca cttttgctat cacaagtcaa
    84361 atgaacttgt aaaagacctt tctctgcatt tgttattggg aatctagaat ctggagtaaa
    84421 tccatagttt ggtatttctt cattattttc tttatattta tttatacatc tccaaagatt
    84481 ttcttcatca gccccaaaaa tgaatcttat cctcttatta aagtctacat ttaaatccat
    84541 aagagctttc actgcataaa ttgctgatat tgtaggtcct ttatcatctt gtgttcctct
    84601 tccatacaat ttaccatctt ctaaaacagc ttcaaatgga gggtaattcc agctttctaa
    84661 atcaccttct ggaaccacat caacgtgacc aagtatacct atcatttttt caccttgtcc
    84721 tatttctgca tatccataat atccatcttt gtatactgtc ttaaatccta aagatttaca
    84781 taagtctaat atacctctta aagctttatc tacattttca ccaaatgggc aattttcagt
    84841 tgcttcagat ataacactag gtatttttac actttcttgt attgaagaaa tcatttcatc
    84901 ttgtagagaa tttacttttt ctttaatttg ctctttcata ttatcaccct tcaattttca
    84961 tcataatata ctaataaata ttttgacctt tttaaaaaaa aatatgctta ttttttcagt
    85021 ttttttataa attcaatcgc ttttaaagtc cccatttttg aatggtcaaa tgtaagtcca
    85081 ccttgaaaat aaacattata aggaggtctt attggagcat ctgcacttaa ttctatagaa
    85141 gaaccttgta taaatgctcc tgctgccatt atgacttcac tttcgtatcc aggcatgtcc
    85201 caaggaacag gttttacata agaatcgact ggtgcagctt cttgtatacc ttcacaaaaa
    85261 cttattactt catcagcatt attaagtcta atacattgaa taatatcact tcttaagtca
    85321 tcatattttg gtaatacatc atatcctaat ttttcaaaag ctcttgagca aaagatagct
    85381 cccattacag cctgagatac tatataaggc gccaagaaaa aaccctgaag tacatttcta
    85441 gttgttccaa aagtaagacc acattctttt cctattccag gagaagtcat tctataagat
    85501 ataagctcaa tcaaatcttt tctaccagct atatatccac ctgtcaatgc aagcccacca
    85561 ccaggatttt ttattaaaga gccagccata acatctgctc caacatcagt aggctctttg
    85621 gtatctaaaa actcaccata acaattatca accattacta tagcttctgg tttaacagac
    85681 tttattactt ctatagcttc ttttatatca ctaattgaaa gtgattttct ccaagaatat
    85741 ccttttgacc tttgtatcat aacgagttta gttctatcat ttattttgtt tttaattcct
    85801 tctaaatcta agtttccatc ctctaaaaaa tctacatcat catatgtaac accatactct
    85861 ttcaatgaac ctttttcttc tcttatgcct ataactccct ctaaagtatc atatggtcta
    85921 ccagtaacag ataaaatttc atctcctggt ctaactatac cttgtataca taaagtaagt
    85981 gcatgtgtac catttacaat tattggtctt acaagagcat cttctgtatt aaatacttta
    86041 gaataaattt cctctatttt ttcacgacca atatcattat atccatatcc tgtagtccag
    86101 ttaaagtgca tatcacttag tttagattct tgcatagctt ttaaaacttt atattgatta
    86161 tattctctta tttcttttat ttcttcaaac ttatctttta tttcttccat tatttcttgc
    86221 gatagtttaa aagtatcatc atctattcca tagtagtctt ttaataattc ttttgtctca
    86281 ttaagcattt tatcacctgt ctctttatta ttttatttaa acatgtaaag gagactattt
    86341 tactaaaaca aataaattat agtttataag ttagtataag tctcctctca atcatcttaa
    86401 attaaattaa ttatctatct gttgttatta ttattgttgt tttggttttg atttgttaga
    86461 ttaatatact ttccaggttg tatagttgat acagcatgtt tataaatcat gttttgttgt
    86521 ctattatccc cttctattaa tattatataa ctatcaaacc cctttacaag ccctttaact
    86581 tgcactccat taactaaata tatagtaaca ggtatccttt ctttccttgc attatttaaa
    86641 aacaaatctt gtaaatttaa aactgtattt ttcattagat ttgtaccctc ccaagattaa
    86701 attgaacttc taaaatattc ctaccttata ttctatataa gttatgacaa attttcaata
    86761 ttaagttgta tacttaaaaa tttatatatt attttataga atctttaata tataagatta
    86821 tttcattttt taattcgtct atattttcat attggtctaa atcaaaccat cttgctgttt
    86881 tatatctttt aaaccatgtt atctgacgtt ttgcatacct tctagaatct cttttaatta
    86941 tttcaatagc ttcttcgtat gtatattctc catccagata cttcaatatc tctttataac
    87001 ctataccttg cattgatatc atatcttttt taaatcccat acttaaaagt ttttttacct
    87061 cttcaaccaa tccattttta atcataatat caactctcat atttattctt tgatacaaat
    87121 gttctctatc tctatttaga actattatta ttggttgata ttcttcatta aattttaaat
    87181 cacttgaaaa atcattcatt ttcttaccac ttagacaaac ttcaagagct cttatgaccc
    87241 ttttagtatt gtttttatgg attctattag cagattcttc atcaagttct tttaacttat
    87301 tatgcatgta atctattccc ttttcagcaa gctgtttttg aagttcttct cttaattcat
    87361 tattggcatc agattgtgca aaatccatat tatatattaa agagtttaaa taaagtcctg
    87421 tgcctccagt tactaaaaca cattttccct tttcatttat ttcatgtata tatttttttg
    87481 ctctttgttg aaactctgaa actgaaaatg gatagtcagg cttaacttca tctataaggt
    87541 aatgcttcac tccttgcatt tcttcctctg taacttttgc acttccaata tccatatatt
    87601 catatatttg catagaatca gctgaaatta tctctgcatc tatatctttt gctaatttta
    87661 ttgacaaatc tgtttttcca acagcagttg gacctgtaag tattataagt ggtatttttt
    87721 tcataacatt cctttccata tattttaaat atccaaatat tttacataat tcttttaaac
    87781 attttttcta tttctgtctt agatatttcg accattatag gtcttccatg agggcatgta
    87841 aatggattct cacacttttc tagctgttcc aataaacttt ttatttcaat atcgtatatt
    87901 ttatcatttg cttttatagc agacctacat gccatagatg caaatctctc tccttttaaa
    87961 tcataattac ttgtaatttc ttctatatta tcaattattt gaagtataaa tttctcagtt
    88021 tcaggtactc caaatatagt aggaacacat cttaccatta tatgattatt gccaaaaatt
    88081 tctagttcaa aaccaaattt cataaataac tccaagttat tttcaatttg aagcatatct
    88141 acatttgata cttcaataac cactgggtct aaaagtattt gcatattgat atcttgtcta
    88201 tagaacttct ccatatatct ttcatatagt attctttcat gtgcagcatg ttggtccaac
    88261 aaatacatag aatcgtcttt gctcaaaatt atataagtat taaatacaac tccaattaca
    88321 gaatatccat ataaggaaaa cttgcgtttt gaactacaca agtattcttc ttcactgtcc
    88381 ttaatactat ctcctaagta ataatttcct tcatttttaa ttccatcaac ttgaaactct
    88441 tcttgtatat tatcatttgc actatcttca cttagataat taatgttttt tacatcatct
    88501 tctacacttg catttaggac ttcacttact gattgaaatt catttattgg tttttcactt
    88561 gataaagtca caacttcaat gacttcatcc ttatctttag taatattact atttttagga
    88621 gtagattcta ataaatcatt atttcttaat ttataatctg tacttttttc tctactgtta
    88681 atagcgattc taggttgtgt ttttttatca ctataagtag catattttcc aataagattt
    88741 gagtgtatta atttaacctt taaaaaatct ctaagttcta tatacacttc ttgttctttt
    88801 tcaaatttaa tttcaagttt attggggtgt atatttacat ctatacatga tgggtctact
    88861 tctatattta agaagcacac tgcatgttta cctattggaa ttatagactt ataactttct
    88921 gttattgcat ctatgattat tttacttttt acaaatcttt tatttatata gatatgttgt
    88981 aagtttttat ttgaacggta tatattgtta ttacctatat atccattcat tttaaagtga
    89041 ttgcacttaa actctacatc tattatattt tccgttattt cttttccata tatacttcta
    89101 atagtgttta caagttttcc atcccctgga gtatttaaca tctgtttatt gttatttgta
    89161 tatttaaatt gaatgtttgg attacctatt gcaagtttat ttatcaaatc acttatgttt
    89221 atagtttctg catgagtaga ttttaaaaat ttctgtcttg ctggtgtatt aaagaaaata
    89281 tcttttataa tgatggtagt tccattagta gaacctattg gttcttttga tattattttt
    89341 ccgccttcaa catatatttt agttcctatt atttcatctt tagttttagt cgtcatttct
    89401 aattttgata cagctgaaat agatgccaat gcttctcctc taaaaccaag agagtataaa
    89461 tcatacaaat catcaatttt tttaatttta ctagtagcat gtctcaaaaa tgatttttca
    89521 acttcacttg aaggtattcc tattccatta tctgtaatct taattagact ttttcctcca
    89581 tcaattatat ctatggaaat tttatttgca cctgcatcaa tggagttttc aataagttct
    89641 tttactacag aagaaggtct ttctacaact tcacctgctg ctatcttatt tatagtcaaa
    89701 tcatctagga tgttaattat atttttcatt tttacacctc taagatttta tttcttttgc
    89761 ttttctttga agattataaa gagagtttat agcatctaat ggagtcatat ttaaaatatc
    89821 cagatttaaa atttcttctg atagtatatc tctatttaca ctatcaaaag agatttgagt
    89881 taaggctact tcttttacag aatcttcttg attaattttc tctttatcat cattttgctt
    89941 cattaaagca acttcatcat ttaatgcttt aaatttagaa tttaatttat cataatcctt
    90001 ttttatatgt ttgtagtctt ttactataag ttcatgttct atttttagag attcatattt
    90061 attcttaaaa ttactttgat ttaccttaac taattcttcg tccaaattac tattaattat
    90121 attattgttt tctttatctc catttattgc aacactgttg taaacatgat ttttttccaa
    90181 gtctttaagt atatattttg ctctttctat gacttcgtct ggtaatttag ctaatttagc
    90241 aacatatatt ccataactct tgtctgctcc ctgaggaatt atttttctta aaaatattat
    90301 tccttcccca tcttctttga ctgctattga ataattttta acctctttaa actcttcttc
    90361 taaatcagta agttcatgat aatgtgttgc aaataatgtc ttacatctaa tatttttttg
    90421 aatatattcc actattgacc atgctaaact tatcccatca taggtactag ttccacgacc
    90481 tatttcatct aatataacta aacttctctc tgttgcattt tttaatataa gggatacttc
    90541 attcatctct accataaaag tagattgacc ttgagataaa tcgtcactag ctccaactct
    90601 tgtaaatatt ctatctaata ttggaatatc agcagactct gctggtacaa atgagcctat
    90661 atgtgccata agagctatta tagcagtttg tctcatatat gttgatttac ctgacatatt
    90721 aggaccagtt attatgttaa taatgttttc tccacgattt aaataagtat catttggaac
    90781 gaaattctcc tctcctacta tattttcgac aacaggatgt ctaccatttc ttatatcaag
    90841 tttattattt tcatttattg ctggttttac atagttattt atatgtgcaa ctgttgcaag
    90901 ggacacaaaa acatctatat tagctatagt cttagccact ttttgtattc tatctatgtt
    90961 tttatatatt gtatctctta tctctacaaa tatctcgtat tctaaagatt taatcttttc
    91021 ctctgcatgt agtatctttt cttctatttc ctttaattct ggagttatat atctttctgc
    91081 attactaagt gtttgctttc ttatatatgt ctcatctagc tttgcctgtt taaagttggc
    91141 ttttgttatt tctatataat atccaaaaac tttattaaat cctattttta atgatttaac
    91201 tcctgttttt tctctttccc tgttttctat ttcctttaca agaaaggctc cattcttaga
    91261 aatctctctt agttccttaa gttcatcact aaaatctgat ttaattatgt ttccatcttt
    91321 tatggttatc gtaggttctt ctagaatagc ttcatctatt aaattgtata tatcatctaa
    91381 tttatccatt tctgaaacat actcttttag gatttttgca tttgataaat ttatagtatc
    91441 ttttaaatta ggtaactttt ctatcgaatt ttttaagtga attaactctt ttggtgttac
    91501 tctctcaaat gctatctttc cacatattct ttctatatcg tatatatttt taagtatatc
    91561 atttaggtct tctcttaata taaagtcatc ttttatttct tctattacat ctaatctatt
    91621 ttcaatttta gatttattta tcaaaggttc ttctacatat tttcttaaaa gtctacctcc
    91681 cattgctgta gaagttttat caagtacatg taataatgaa ccttttttct tattccctct
    91741 tatagtttga gtaagttcta aattagttct agtaaacata tctaaaacca tatattctga
    91801 tgaattgtat atatttatat tattaatgtt agatgttatt tgtttttgag tattgtatat
    91861 ataattcaga agaattgata agcttgactt tattagacct ttatcatcaa actttagttt
    91921 ttgtagataa acatctggaa aatattcttt taatatattt atatccaaat agttatcact
    91981 aaaactttca tttatgtata tattacttac agtagctata tctctaagct tttctataaa
    92041 gtctaaatca tttataatta tttcagttgg atggattttt gcaatttctt caattacctt
    92101 atcttcattt aaacatgttg cattagtttc tcctgtactt atatcaacat aagttagacc
    92161 tatattagta ccatccttat acaaagataa taaataatta ttctttttat tttcaagtaa
    92221 atttccatct aaaactgtac caggagtgat gactcttata acctctcttc taacaattcc
    92281 ttttgctgta gatgggtctt ccatttgttc acctattgct actttatatc cattttcaac
    92341 taattttgat atatatgaat tggctgagtg gaaaggaaca ccacacatag gagcacgttc
    92401 ttctaaacca caagcttttc ctgtcaatgc tatttcaaga gcttttgaag ctactaatgc
    92461 atcttcaaaa aacatttcat aaaaatctcc aagtctaaaa aacagtatac agtctttata
    92521 tctatttttt acttcaagat actgtttcat cataggagtt aatttattca tatctatttg
    92581 cattatcaaa cctccttctt ttctaattaa atattatatc atagtagatg attattatta
    92641 acacaatata taaaattttg acatataact aaaaacaatc caaaatgtat actcacattt
    92701 tggattgcta agtttaatgc ttattaaata aaaatatata tatttttaca ataaagatat
    92761 tatttctttt ttaagtttaa tgatattttc aaggttatct tcatttaact ttctactatc
    92821 tataacaaat tctttcttta ctattgatgg tttttttgaa ataacataaa ttctgtttga
    92881 tagcattata gcttcgtcaa tatcatgagt tataagaagt attgttgaat ttactttttt
    92941 cttaacatct aaaagccatt tttgcatgga tgttttagtt aatgaatcaa gtgccccaaa
    93001 aggctcatct aaaagcatta tgtcattaga atttataaaa gttctcaaga agttagctct
    93061 ctgtctcatt cctccagaaa gttctgaagg atatttatct tcatatccgc ttaatccaaa
    93121 cacctcaaaa taaggtttta ccattgacct agctttactc tttttttctt tttttaaaat
    93181 tagtggtagt gacacattat ctattatagt tttatatggc aagagtaaat ctttttgata
    93241 catataacta tatttaccat ttatattcac tttgccacta tcataatctg taagtttagt
    93301 tataatatta aaaatagtac tttttccaca tccacttggc cctaatatag aaacaaactc
    93361 accttcataa acatcaatac ttatatcttt taaaacttca atatctttat aagtttttga
    93421 tacattttct atagatactt ttactttttt attgtggtaa aaattcattt gtgtaagcat
    93481 cacttgcctt catatcctta tctattaatt tatattcttt taagaatgat gtatagttgt
    93541 tccatacact atctttcatt tctccccatc gtggtgcatc atctttgtac ttgcttgcta
    93601 aatattcttg actctttaaa gctagttttt catctacttc aggtgcatgt tttactaaaa
    93661 tttttgctga ttcttctgga ttttttattg catattcata accttttgtt gtagctttta
    93721 agaatttttt agcaagctct ggattatctt taagcacagt ttcattagaa attataagtg
    93781 gtgtataata atccaatctc tcatctaaat cttttactgg tataaagttt aagtcatatc
    93841 caattaaatc agctttaact gcatcccaac cttcaaatat ccatgcaaaa tctacagttt
    93901 tcatagctgc aaagaaatca tcttgaccag tattaactat ctttaactta ttaaaatcag
    93961 ctccattttt cttcataact gctttaaaaa cagcttcttc tgatggagag ccccaaccac
    94021 cataagtttt tccttcaaaa tctttagctg ttgttatatt cttttctttt ggtgatgcaa
    94081 acccagaagt attatgttgt ataacagttg ctacagcttt tattggaagt ggatcttcac
    94141 tagtctttgc ataagtaact tgttcttgat agcttatacc aaagtcagct tttcctgttg
    94201 ctactaaagt ttctgctcca ctttcaggtg gttgtactat ttcaacatcc aaaccttctt
    94261 ctttatagta acccttatca agtgctacaa ataatccagt atgatttgta tttggtgtcc
    94321 aatcaagcac catagttact tttttagaag aagtatcttt atcattgttt ttgtctttat
    94381 tgttatttga agaacatcca gttattgttg ccaatgtaaa aacacttact aaacctaata
    94441 ttcctaactt tttaaaattc ataattgcct ccctcaaata cctttaatca attaatctat
    94501 gtcttataac aacttttttt acagcctgta caattcctac aaacattaaa ctaaatataa
    94561 ctactaatat agtagatgca aatactttat caagtgcata tgcacttttt gacctaagca
    94621 tataaacacc aagtcctttc gttccaccta gccattctgc aacagttgct gccattacag
    94681 catacgttgc agatatttta agtccagaaa aaaatttatc cattgccata ggaaatttaa
    94741 ggtgaatgaa tgtattaact ttatttgagt ccatagtctt aaataaattt aaataatctt
    94801 tatcaatatt ctcaatgcca tctacaaaac ttattaatat aggaaaaaaa caagtaagca
    94861 ttaccatcaa tacttttggc attgttccaa atccaaacca tatcataaaa agtggtgcta
    94921 taattattgt aggtatcatc tgtgtaacca acataatagg ataaagacat ttttttatta
    94981 ttgatacaaa atccatcaat attccaatta ccaatgatat tataattgcg actataaaac
    95041 caagtattgc ttctcctata gtaaccacag catgcatgga taaattttga taatctttaa
    95101 aaaacacatt aattatatct actggtgtgg gtagtatata ctgaggaact tctaaaactc
    95161 ctaccataga ttgccaaaga ataagtataa acaaaaatgt tgctattgga tatatactat
    95221 ctttgacttt atctatgatt tctaagtttt tcatctatag tcagacctcc agctttttca
    95281 tctactctag ctactgttat gactctttca catccaagat taaaagggat tttatgtacc
    95341 ttttttaata attcaaaaac ttcatcaaaa tcaccttcaa cagtagtgct cattgctcct
    95401 atttcacatt taagaccact tttttcaatt tcagcaatac aagcatctac tactttatac
    95461 atttcttctt cacctttgta aggtcttagt ggcattactg ctatgtctgc gattaccatt
    95521 taaatcactc ctttaaaaat aattaatacc tactaggtat attttgtttt ttattaaaaa
    95581 attttattac taaaaagata ttatatttaa ataaaagaaa agtcttatcc aaaataggat
    95641 aagacttatt tttatcttaa ctggtctccc tacactggca ttatccaaac aggttcaaag
    95701 ggtcgagata aaatctcctc tcagcacatt agctccccga aatatattat atcttttcta
    95761 cttgattata ctacacttat catattttaa caaatttttt atttatatta gatattttat
    95821 ccgttcaaaa atatctaata tacattgtac attattacac caaataaatt atcttaaaat
    95881 ggtaatttat caacatcttc caaaactaga ttaactgaat tttctagttt ttattttgct
    95941 atttcaagca tatttggatg tatatcaatt ccatacaaat attgttctaa atttctgttt
    96001 tcactaatct aatttgcaat cgttacagat tacagattag aaatagcttt tagactctac
    96061 ttatctttat ctacaaaaaa tccttcaata aattcagtaa taatattcag taatctaaaa
    96121 ataaacctct atctggattt ttaagataca agccttttag gaagtatctt ttgtgataat
    96181 ataaaaatta ctcgtcatta tcatcaaaat cctcagcaac caacatttta gataagaatc
    96241 aaactctata atataattat tttatccaat ttatttttga gaaataaaat atttttttaa
    96301 tttttaaatt ttttaatatg caccttgaaa aaagaaacgt tttcctatat tatggtaata
    96361 gtagaataaa actaaatagg caaaactaga gaaatttagt gacgcaaagc tatagggact
    96421 aagacttatg aaatgagtta tgtcagccag ttgccaaaga gatattttct ttttgttttt
    96481 atgaatgttt tttaggggga tatatgatat atgtttatgg ataaaatgga tagatgtaca
    96541 catatactaa ctgcatatat atgcagttca cgcgattact gcaattttat agatacacaa
    96601 ttaaatgatt ttatactaga atatggagag aatgtggtag aatcttgttt gcatcaagtg
    96661 atggtattgg taagcagata taattaaaga aattttattt tctagaaaac cctttttagt
    96721 tttatctacg ttttataatt cattaaagaa ctaatcaaaa taagcttcat tatatatttt
    96781 tcatgaagta aacagttgag tttatctcat atactgttta ccccaattac ataattctaa
    96841 taatatagat tccaatgatt taccacgttt agtagacaaa tattcaactt ttggaggaat
    96901 agtcggataa gaaattctct taataagtcc atctctttca agatacttta attcttgtga
    96961 cagtatctta tgacttatat gaacaacatc tttttttaat tgactgtaac gtattggctc
    97021 ttgttttaaa atatgccata aaataattgc cctccattta cttcctatca cagtcatggt
    97081 aaaaccaatt gaacaattaa aatctttttg tctttcttca atatttggaa attcttcaaa
    97141 attattatct atatccatct caatcctctc tttcaaaata gtaagtatct aactaaaaag
    97201 tgcattcttg tttagcgtac taattcgtaa tataatcttg attaaaaaat agctacgcac
    97261 actcgtgact ttagtcatga gttagtagct aaaatagtca
//
LOCUS       DAEQJM010000007        97224 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.007, whole genome shotgun sequence.
ACCESSION   DAEQJM010000007 DAEQJM010000000
VERSION     DAEQJM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 97224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97224
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.007"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..2487)
                     /locus_tag="KRQ43_000612"
     CDS             complement(<1..2487)
                     /locus_tag="KRQ43_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH2740984.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQST
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANQG
                     VYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGG"
     gene            2701..3399
                     /gene="yunB"
                     /locus_tag="KRQ43_000613"
     CDS             2701..3399
                     /gene="yunB"
                     /locus_tag="KRQ43_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HBH2740985.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(3611..4618)
                     /locus_tag="KRQ43_000614"
     CDS             complement(3611..4618)
                     /locus_tag="KRQ43_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH2740986.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNSEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISNLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            4846..5730
                     /locus_tag="KRQ43_000615"
     CDS             4846..5730
                     /locus_tag="KRQ43_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH2740987.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDKKNKIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            5932..7482
                     /locus_tag="KRQ43_000616"
     CDS             5932..7482
                     /locus_tag="KRQ43_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH2740988.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKEKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            7511..8146
                     /locus_tag="KRQ43_000617"
     CDS             7511..8146
                     /locus_tag="KRQ43_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBH2740989.1"
                     /translation="MKKFLNVLFSVCISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSEDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVFLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPNLDPVINILPEEFFFHSGMMILILILLASILLFVMYRLYKSFKIK"
     gene            complement(8257..8517)
                     /locus_tag="KRQ43_000618"
     CDS             complement(8257..8517)
                     /locus_tag="KRQ43_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HBH2740990.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCMLPHKKDNYNYIMGKFQDLVKITSKK"
     gene            8734..10017
                     /gene="hflX"
                     /locus_tag="KRQ43_000619"
     CDS             8734..10017
                     /gene="hflX"
                     /locus_tag="KRQ43_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH2740991.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTSESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGENGITLDVNFDEEDFNIYREYILEK"
     gene            10025..10702
                     /locus_tag="KRQ43_000620"
     CDS             10025..10702
                     /locus_tag="KRQ43_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBH2740992.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEAGEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            10788..11231
                     /locus_tag="KRQ43_000621"
     CDS             10788..11231
                     /locus_tag="KRQ43_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH2740993.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTNCVLAPEFQE
                     GGFYKVKDALDMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            11537..12181
                     /locus_tag="KRQ43_000622"
     CDS             11537..12181
                     /locus_tag="KRQ43_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBH2740994.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVVVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITNGTGKIILGEEFYLSEQNGEILI"
     gene            complement(12267..12644)
                     /locus_tag="KRQ43_000623"
     CDS             complement(12267..12644)
                     /locus_tag="KRQ43_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH2740995.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(12644..13030)
                     /locus_tag="KRQ43_000624"
     CDS             complement(12644..13030)
                     /locus_tag="KRQ43_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH2740996.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            13209..13964
                     /gene="nadE"
                     /locus_tag="KRQ43_000625"
     CDS             13209..13964
                     /gene="nadE"
                     /locus_tag="KRQ43_000625"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HBH2740997.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYRAEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            14047..14766
                     /locus_tag="KRQ43_000626"
     CDS             14047..14766
                     /locus_tag="KRQ43_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH2740998.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(14934..15938)
                     /locus_tag="KRQ43_000627"
     CDS             complement(14934..15938)
                     /locus_tag="KRQ43_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH2740999.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            16204..17100
                     /locus_tag="KRQ43_000628"
     CDS             16204..17100
                     /locus_tag="KRQ43_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HBH2741000.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            17238..18500
                     /locus_tag="KRQ43_000629"
     CDS             17238..18500
                     /locus_tag="KRQ43_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741001.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            18576..19769
                     /locus_tag="KRQ43_000630"
     CDS             18576..19769
                     /locus_tag="KRQ43_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH2741002.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LKRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            20398..21192
                     /locus_tag="KRQ43_000631"
     CDS             20398..21192
                     /locus_tag="KRQ43_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH2741003.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            21286..22626
                     /locus_tag="KRQ43_000632"
     CDS             21286..22626
                     /locus_tag="KRQ43_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH2741004.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            22763..23995
                     /locus_tag="KRQ43_000633"
     CDS             22763..23995
                     /locus_tag="KRQ43_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH2741005.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            24035..25177
                     /locus_tag="KRQ43_000634"
     CDS             24035..25177
                     /locus_tag="KRQ43_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH2741006.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGTDIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGIGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASSTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            25188..25982
                     /locus_tag="KRQ43_000635"
     CDS             25188..25982
                     /locus_tag="KRQ43_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH2741007.1"
                     /translation="MNIVVCLKQVSDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFAPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            25993..27015
                     /locus_tag="KRQ43_000636"
     CDS             25993..27015
                     /locus_tag="KRQ43_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH2741008.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELEVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEVLPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            27114..28490
                     /locus_tag="KRQ43_000637"
     CDS             27114..28490
                     /locus_tag="KRQ43_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH2741009.1"
                     /translation="MKEQWYKDIFARILSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKDKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(28822..29166)
                     /locus_tag="KRQ43_000638"
     CDS             complement(28822..29166)
                     /locus_tag="KRQ43_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741010.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            29654..30664
                     /locus_tag="KRQ43_000639"
     CDS             29654..30664
                     /locus_tag="KRQ43_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH2741011.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEESTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            30800..31288
                     /locus_tag="KRQ43_000640"
     CDS             30800..31288
                     /locus_tag="KRQ43_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH2741012.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            31464..33392
                     /locus_tag="KRQ43_000641"
     CDS             31464..33392
                     /locus_tag="KRQ43_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH2741013.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFILSNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFENLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            33567..33977
                     /locus_tag="KRQ43_000642"
     CDS             33567..33977
                     /locus_tag="KRQ43_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBH2741014.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            33999..34301
                     /locus_tag="KRQ43_000643"
     CDS             33999..34301
                     /locus_tag="KRQ43_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HBH2741015.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(34517..35209)
                     /locus_tag="KRQ43_000644"
     CDS             complement(34517..35209)
                     /locus_tag="KRQ43_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH2741016.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMMAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(35235..36422)
                     /locus_tag="KRQ43_000645"
     CDS             complement(35235..36422)
                     /locus_tag="KRQ43_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2741017.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRIPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSISYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            36758..38635
                     /locus_tag="KRQ43_000646"
     CDS             36758..38635
                     /locus_tag="KRQ43_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH2741018.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKTVYDEVIKIVPQSNDVGKKNESQEKQSIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSFIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            38947..40353
                     /locus_tag="KRQ43_000647"
     CDS             38947..40353
                     /locus_tag="KRQ43_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH2741019.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNTVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            40381..41229
                     /locus_tag="KRQ43_000648"
     CDS             40381..41229
                     /locus_tag="KRQ43_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH2741020.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            41890..42582
                     /locus_tag="KRQ43_000649"
     CDS             41890..42582
                     /locus_tag="KRQ43_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2741021.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            42579..43514
                     /locus_tag="KRQ43_000650"
     CDS             42579..43514
                     /locus_tag="KRQ43_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2741022.1"
                     /translation="MKMDEQTIILFLFLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGNENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIGQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVDDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTVFTVSLPLI"
     gene            43662..44585
                     /locus_tag="KRQ43_000651"
     CDS             43662..44585
                     /locus_tag="KRQ43_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741023.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRKFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAHAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            44569..45339
                     /locus_tag="KRQ43_000652"
     CDS             44569..45339
                     /locus_tag="KRQ43_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741024.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVTVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            45349..46131
                     /locus_tag="KRQ43_000653"
     CDS             45349..46131
                     /locus_tag="KRQ43_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741025.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGIAVLLSLFSFLCTFILGLLFCNINISVTLIVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            46508..47044
                     /locus_tag="KRQ43_000654"
     CDS             46508..47044
                     /locus_tag="KRQ43_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH2741026.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            47076..47465
                     /locus_tag="KRQ43_000655"
     CDS             47076..47465
                     /locus_tag="KRQ43_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH2741027.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            47502..47888
                     /locus_tag="KRQ43_000656"
     CDS             47502..47888
                     /locus_tag="KRQ43_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBH2741028.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGSQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            48015..49457
                     /locus_tag="KRQ43_000657"
     CDS             48015..49457
                     /locus_tag="KRQ43_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH2741029.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVENESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLIDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            49754..50569
                     /locus_tag="KRQ43_000658"
     CDS             49754..50569
                     /locus_tag="KRQ43_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2741030.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINNFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKRVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
     gene            51170..52354
                     /locus_tag="KRQ43_000659"
     CDS             51170..52354
                     /locus_tag="KRQ43_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741031.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(52731..53840)
                     /locus_tag="KRQ43_000660"
     CDS             complement(52731..53840)
                     /locus_tag="KRQ43_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH2741032.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            54303..55496
                     /gene="nifV"
                     /locus_tag="KRQ43_000661"
     CDS             54303..55496
                     /gene="nifV"
                     /locus_tag="KRQ43_000661"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HBH2741033.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVI
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            55521..57446
                     /locus_tag="KRQ43_000662"
     CDS             55521..57446
                     /locus_tag="KRQ43_000662"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HBH2741034.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSNVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            57468..58463
                     /locus_tag="KRQ43_000663"
     CDS             57468..58463
                     /locus_tag="KRQ43_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HBH2741035.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGAEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            58790..59263
                     /locus_tag="KRQ43_000664"
     CDS             58790..59263
                     /locus_tag="KRQ43_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2741036.1"
                     /translation="MVGSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDEFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            59297..59791
                     /locus_tag="KRQ43_000665"
     CDS             59297..59791
                     /locus_tag="KRQ43_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2741037.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            59888..60409
                     /locus_tag="KRQ43_000666"
     CDS             59888..60409
                     /locus_tag="KRQ43_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH2741038.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMYDDNIEADKYIREELKVPSKYSVECIISIGYSDEEKKAYND
                     SDLDYKKVHFNNF"
     gene            60598..60909
                     /locus_tag="KRQ43_000667"
     CDS             60598..60909
                     /locus_tag="KRQ43_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH2741039.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            60937..61623
                     /locus_tag="KRQ43_000668"
     CDS             60937..61623
                     /locus_tag="KRQ43_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH2741040.1"
                     /translation="MKYSYKKCIIDSILLMFIIQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            61855..62739
                     /locus_tag="KRQ43_000669"
     CDS             61855..62739
                     /locus_tag="KRQ43_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH2741041.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            62838..64013
                     /locus_tag="KRQ43_000670"
     CDS             62838..64013
                     /locus_tag="KRQ43_000670"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HBH2741042.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEELLKDIPTANKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            64141..64995
                     /locus_tag="KRQ43_000671"
     CDS             64141..64995
                     /locus_tag="KRQ43_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741043.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSNESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKIKDDSSC
                     LYLDIYND"
     gene            65039..66274
                     /locus_tag="KRQ43_000672"
     CDS             65039..66274
                     /locus_tag="KRQ43_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBH2741044.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREIVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKSISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYISLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNEKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            66375..67316
                     /locus_tag="KRQ43_000673"
     CDS             66375..67316
                     /locus_tag="KRQ43_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HBH2741045.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(67545..67898)
                     /locus_tag="KRQ43_000674"
     CDS             complement(67545..67898)
                     /locus_tag="KRQ43_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH2741046.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMIW
                     LEKLKEDNTYEIYSI"
     gene            68194..69105
                     /locus_tag="KRQ43_000675"
     CDS             68194..69105
                     /locus_tag="KRQ43_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HBH2741047.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            69365..69799
                     /locus_tag="KRQ43_000676"
     CDS             69365..69799
                     /locus_tag="KRQ43_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741048.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            69822..71357
                     /locus_tag="KRQ43_000677"
     CDS             69822..71357
                     /locus_tag="KRQ43_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741049.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVIYK
                     IDCDVILVNLFELIINNCIFSTILGNEVINLEISKYEYEFLEKQFKNMYNNITEDKVI
                     GSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKNEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKTEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            71441..72808
                     /locus_tag="KRQ43_000678"
     CDS             71441..72808
                     /locus_tag="KRQ43_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2741050.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKARDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMNTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            72843..73067
                     /locus_tag="KRQ43_000679"
     CDS             72843..73067
                     /locus_tag="KRQ43_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HBH2741051.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(73517..73915)
                     /locus_tag="KRQ43_000680"
     CDS             complement(73517..73915)
                     /locus_tag="KRQ43_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HBH2741052.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMVG"
     gene            complement(73918..74319)
                     /locus_tag="KRQ43_000681"
     CDS             complement(73918..74319)
                     /locus_tag="KRQ43_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH2741053.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLVAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            74678..75664
                     /locus_tag="KRQ43_000682"
     CDS             74678..75664
                     /locus_tag="KRQ43_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741054.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLNEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            75648..76559
                     /locus_tag="KRQ43_000683"
     CDS             75648..76559
                     /locus_tag="KRQ43_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741055.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIRNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            76672..78240
                     /locus_tag="KRQ43_000684"
     CDS             76672..78240
                     /locus_tag="KRQ43_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2741056.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHVLEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            78315..79340
                     /locus_tag="KRQ43_000685"
     CDS             78315..79340
                     /locus_tag="KRQ43_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741057.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDEYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            79333..80277
                     /locus_tag="KRQ43_000686"
     CDS             79333..80277
                     /locus_tag="KRQ43_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741058.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            80636..82294
                     /locus_tag="KRQ43_000687"
     CDS             80636..82294
                     /locus_tag="KRQ43_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2741059.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERDSKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASNGKSSW"
     gene            82275..83291
                     /locus_tag="KRQ43_000688"
     CDS             82275..83291
                     /locus_tag="KRQ43_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH2741060.1"
                     /translation="MVKAVGDIIGKCSAISFDMKLDKSYDEVIVDFKNLINNIDNKDV
                     LLFTDMGSLNSFDEIIKKEKKCEVRVIPMVTTLTVLEAVQKANMGLPLNDVYNSITNT
                     RKYYFGTNEIQNKENLSKTIIIASHVSEGVDNKTRKILEEKMSRYLDGIDIISVPYKT
                     EKDLSLNITKLKESSNIVAVINEQRINIRGIDYISKKDIDKDENINKLKNIIKISIGY
                     DDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLVFNIEKKYDKVIGLMMHLAFMVDGLI
                     GNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDKKYNIEINEKECYQILLILEYAEIIE
                     KDYQ"
     gene            83506..84135
                     /locus_tag="KRQ43_000689"
     CDS             83506..84135
                     /locus_tag="KRQ43_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741061.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            84270..84596
                     /locus_tag="KRQ43_000690"
     CDS             84270..84596
                     /locus_tag="KRQ43_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2741062.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            84612..85901
                     /locus_tag="KRQ43_000691"
     CDS             84612..85901
                     /locus_tag="KRQ43_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2741063.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            85925..86254
                     /locus_tag="KRQ43_000692"
     CDS             85925..86254
                     /locus_tag="KRQ43_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH2741064.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            86402..87730
                     /locus_tag="KRQ43_000693"
     CDS             86402..87730
                     /locus_tag="KRQ43_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH2741065.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            88047..88907
                     /locus_tag="KRQ43_000694"
     CDS             88047..88907
                     /locus_tag="KRQ43_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HBH2741066.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            89112..90092
                     /locus_tag="KRQ43_000695"
     CDS             89112..90092
                     /locus_tag="KRQ43_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2741067.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVICGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
     gene            90295..90744
                     /locus_tag="KRQ43_000696"
     CDS             90295..90744
                     /locus_tag="KRQ43_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741068.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARVLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(90905..91834)
                     /locus_tag="KRQ43_000697"
     CDS             complement(90905..91834)
                     /locus_tag="KRQ43_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741069.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            92027..92839
                     /gene="modA"
                     /locus_tag="KRQ43_000698"
     CDS             92027..92839
                     /gene="modA"
                     /locus_tag="KRQ43_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH2741070.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKTDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEVESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            92988..93671
                     /gene="modB"
                     /locus_tag="KRQ43_000699"
     CDS             92988..93671
                     /gene="modB"
                     /locus_tag="KRQ43_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBH2741071.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            93672..94748
                     /locus_tag="KRQ43_000700"
     CDS             93672..94748
                     /locus_tag="KRQ43_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBH2741072.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            94754..95311
                     /locus_tag="KRQ43_000701"
     CDS             94754..95311
                     /locus_tag="KRQ43_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH2741073.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(95475..96497)
                     /locus_tag="KRQ43_000702"
     CDS             complement(95475..96497)
                     /locus_tag="KRQ43_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2741074.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRIGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(96628..>97224)
                     /locus_tag="KRQ43_000703"
     CDS             complement(96628..>97224)
                     /locus_tag="KRQ43_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2741075.1"
                     /translation="GLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQS
                     LSLIMSCLTSPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALH
                     YGDRLIMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
BASE COUNT        37001 a        11066 c        17408 g        31749 t
ORIGIN      
        1 accgccacca ttatcacctg tgttattatt gttattatta ttttcttctg gttggttatt
       61 gtctggtttt tttgtatctt cagatgatgg ttgagaactt actttagtag gagcagtacc
      121 ttcaataaat gctgctttag agccagaaga ttgctttcct ccatcctcta aattaatttt
      181 tgtaaaatat acatttttag gaacttcaaa ttcagtaacc gttaaattag catgtatttt
      241 ttccataatt ttttcccata gttttgcagt actagtactt ccatgtggta cttctctacg
      301 ttttatagtg ttaccagaat catcttttct accagcatca tctccaatat aagttgcacc
      361 aacataataa ggagtgtaac cgacaaacca agcatcatat gcactatttg tagtacctgt
      421 tttacctgct acaggcattc cctttggaag tgtagcaaca ccaccagtac cttcagtaat
      481 tacgctttct aacatatctg taacaacata agctacttca gggtctacaa ctttatgttc
      541 ttcaggagca tttttaacta ataattgacc atcaaaggta gttatagtag taaaaataga
      601 aggttctaca taaacacctt gatttgccaa tgtaccataa gcagcagcca tttgaagtgg
      661 agtaatacca ttcgccatac cacctagtgt caatgatggg aattttctat cacttgcttc
      721 agatgaacct gagtgattat tctttaaagt tgttatacca aagttcttta agtaatccat
      781 cattatatct acacattcat cataagagtc tccaagcatt tcagcagttt tgacagctat
      841 cgtgtttgaa gatttagcaa gtgctttacg taaactcata gaaccatgac cagcagtagt
      901 agttcttgga ttccatttat tattttcttc aaacttatat cctcctcgag aatcacttag
      961 agcagttgat tgtgttattt ttagggtatc aatagcaggt gtatatattg ctaaaggttt
     1021 tatagaagaa cctggctgat gagggttagt agcacgattc aaagtttttc taccacttat
     1081 atttcttcct ccagctagtg ctcttatttc accattttta taatctaaga ttaccattgc
     1141 agcttgtggt tggctaactc catcagggcc gaccatatgt cctgggaaat tgctatttct
     1201 atcaaattct tcttctaaag catcttgcat tttagggtct atagttgtgt ttacaattag
     1261 accaccattg tagaataagt tttgagcttc atcatttgta tgtccttgtt ccattaaagc
     1321 atttataact tcactttcga taaggtcttc tacagatgaa gaaactttat ctgatgattg
     1381 aggcaatttt atttctattt tagctttgat tgcttcatca tattcacttt gttttatata
     1441 tttcaattct aacattttct ttaaaacaat ttcttgtctt tttttagctt cagggttact
     1501 tacagccttt ctaacaacta atgtacctgc ttttaattgt ctataagtat cattagatat
     1561 aagctcccaa gattttattt tttcaatcat atcaaagtcc acttgagtag ggtcatctaa
     1621 atcatcatca gttgtgttaa caaaaaataa taatttattt tctaaatcct ccttagtttc
     1681 atttccctct aacttagaag ttttataggc tgaaaatctt gatggatttt tagttgaacc
     1741 agcaagaagt gctgactctg ctagagtgag gtcagctgca gacttatcaa aataaccacg
     1801 tgcaccagcc tcagcacctg ctagacctct accaacgaag aagttattta aataagtttc
     1861 tagtatttta tctttactta ctgttttact catctcatgt gcatagtaaa tatcctttat
     1921 tttacgaggt atagtttgct gttcagttgt taacagcatt ttggatacct gcataggaat
     1981 agtactacca ccttgcttag tacctgtaag ggtctttaat actgacctaa ataaaccttt
     2041 aatatcgaca cccttatgct cataaaaacg ctcatcttct attgcaatta cagcatgttg
     2101 aagataaggg gaaatcttat ctaatggaac gggtgtcttt ttatttacac ttggagctgt
     2161 agacaatgtt tttccattag cgtatttaat agtagttgtt tggttcgtct gtttatctaa
     2221 aacagcttct gtaactggag ttacatctct tagtgacgca aatactagac cagcagtacc
     2281 tgctgtacca acaactagta aaactaaaaa tactatccca aatactctta gttttttaaa
     2341 tttatcgctt tttttagatt ttttcttgtt ttttgttgaa cgagtcttgt tagctgaagt
     2401 tctattaatt ggtttatttg tattaccaga tgagctaact ttttttctcc tgattttatt
     2461 tccattttta tcattatcgt tattcataag attttaacct ccttacttaa tgcaatatta
     2521 taacacaaat aggagtagtt ttgtaattaa tagaaaaaat gaatttgcta taatattctg
     2581 tacattgtat atgtataaac gtaatatatt aaaaagtcta tatttttatt ttatttattt
     2641 ttgacaaata ttataaaaat tatgccaaag ctacatataa ataaatagga ggggataatt
     2701 ttgaatagaa tagtagatag aaaaacaaaa aatgaattta gaaaaatcat agctattttt
     2761 ttagtaattc ttttcttgtc tgtatttata ggcagtttta tatatataga taaaacttta
     2821 agaccgacaa taacagtttt agcagagact aaagctcttg aactagcaaa taggtcgata
     2881 aataaagctg ttgctgagat ggtagaagga aaaataaatt atgaagattt aatggatata
     2941 caacttgata ataatggtaa aataactatg atacaagcaa acactataat gatgaatgaa
     3001 attgcatctg caatagcttt agaaatacaa gatgaattaa aaaaggataa gacagcaagt
     3061 tcttacatac ctataggaac agcattagga agtcctatat tagctaaata cggtcctaaa
     3121 cttgaagtgt ctattgaacc tataggaaca gtatcagtaa actttaaaac ggaatttgag
     3181 tcttcaggta taaatcaaac tagacataga atatatttag aagctcaaac acaagttaaa
     3241 gtagtaatac cacttataac ttcaacaaaa caaattaaag ctcaaatacc tatttgtgaa
     3301 actataatag taggtgatgt tccagaaagt tatgtaaata ttccagaaaa aaatctagga
     3361 aatgttttac ctaacactgg aaagaatacc aacaagtaat ataaagttgt atatttttaa
     3421 ataaattcaa aataatagtt tataaataaa atttttggaa ataatattaa tataatttta
     3481 ataaaaattt atattttata ctatgtaaaa tatctaatat atttggtctg taggttaaat
     3541 aaaagtacct ttagaccaaa tatattatta ataacttaat aacatcttaa aacttattta
     3601 tttatattat ttacaacatc catttaataa atacaccata acctacagct gggtcatttt
     3661 caattgcatg tgacactgct ccgattattt tattatcttg aactattgga gtaccactca
     3721 taccttgtac aataccacca gtttgagcta aaagcttttt atctgtaatt ttaattttaa
     3781 aacttttact ttctggatgt ttttggtttt ctatatctat aatttcaata ttatattttt
     3841 tacacttatt aaagttatct tgtaaaatta tttgagcttt tcctaattta acttcatcta
     3901 aagatgctac tttatatttt tttaaattgg aaatatcaaa gttattaatt tgacctctta
     3961 ttccaaaatc agtattttct gtaaagctac caataatatt ttctcgtttt gcatttatac
     4021 atccaacact acctttataa gatttttcta tattaaggtg cttagttgta gaaattgaac
     4081 ctgttttaat aggtattttt cttgcattac caacacttat tggatgacct acagctccaa
     4141 actctgatgt atctggattg atatacgtta aagtagcaaa tccagaaagt aaattgttaa
     4201 aactaatttt ttctaatatg tgtttggtag ttttcattgt tataagttgt ccacctctat
     4261 ttaataaaat agatacttgt ttttcttctg gtaaagcatt taaggtattg gcaaagtcac
     4321 tatatccatc aacttcagaa ttatttacct ttactatagc atcacccaat ctaaatggag
     4381 atgcttctcc aggatttcta actatgatat tttttaattc tgcgtcaatt tgaagtacgt
     4441 ttccaattgg tattaaatat tcaggttcat ttttttgtaa attttgtgca taaattaaat
     4501 tatttgagaa aaaatataat aaaaataaaa atgttaaaac aattgtaaat tttgacttag
     4561 ctaagttggt ttttttactt aaagtattat ttttaaaatg aaaattttta agttgcataa
     4621 aacacctctt tcttattaaa ttattttaat aatagaattg aagttttctt gctgcttcta
     4681 tattatgttg tgcaagaatt atgttttgat gcttggaaaa ctgactcaat aacaccttag
     4741 ttttcataaa aataaataaa ataaatagtg tatatgataa aataaataca tattcatata
     4801 aataaaaata aacaataact gtctagcata agaaaggagc aaaaaatgaa aaaatataga
     4861 ttgttagtta cttgtataat tgccatggga atcataatta taggaacatc aaatccagtt
     4921 agcaattttt acaagactac aaatttgatt agttcaggaa atatcacaaa tgaaaaagca
     4981 gataaagatg aaaattcaaa caaaaataat aaagataaaa atgaagacaa atctaattct
     5041 aaaagtaata aagataagtc atcagaggac aaatcgtcag ataaaaaaaa taaaattcaa
     5101 aaaaataaaa aacttttaat ttgtatagac ccagggcatc aaggaaaagg agatagcaat
     5161 ttagaaccag tagctccagg ttcttcctct aaaaaagcga gagtatcttc aggaacagag
     5221 ggtattgcta caaaaaaacc agaatatgtt ctaaacttag aagcatctct tgttttaaag
     5281 agtatattag aatctaaagg ttataatgta ataatgacta gagagacaca tgatgtaaat
     5341 ataagtaatt cagagagagc aatacttgct aatgataaaa aagcagatat ggttgtaaga
     5401 atacatgcag atagtttaaa taattcttca aaaactggag catctatatt gattcctgaa
     5461 aaagatggaa aatatacagc tcctatatat gaagagagta ataaatgtgc tgaatttatc
     5521 aaacagaata tggaacaatc aggtatacaa atcaatggaa tcgttcaaag aggtgatttg
     5581 actggattta actggtcaaa agtaccagcc gtattagtag aaatgggatt tatgagtaac
     5641 tataatgaag accaaatgat gtcaaatcca gactaccaaa gaaaaatgat gcagtgtata
     5701 gctgatggat tggatgcgta ttttaaataa gatatgaata gagaaaaagt taggttggta
     5761 ttattttcct aatttttatc tctatttttt attgtacata atgcaaagaa gaagtttatt
     5821 ttaggttaaa ttgtcgtaaa tataactaaa aatattggga atacttgatt taagtttaaa
     5881 aagaatatat tatagtatag aatgtgtaaa atttttttga gaggtgttga aatgctagta
     5941 gtagaaaatg tgagtcatgg atttggtgcg agaacaatat tagaaaatgt atcctttaga
     6001 cttagaaaag gtgaacatat tgcactagtt ggtgctaatg gagaaggaaa atcgagtttt
     6061 ttaaatataa taacaaagaa gcttatgcca gatgctggaa atataaaatg gtcttcaaga
     6121 gctacagtag gttacttaga ccaacatacg gtattaagca aggaaaaaac tataagagaa
     6181 gtgcttagag aggcttttaa gcatatgttt gacttagagc aagaaatgat tgctatgtat
     6241 gacaaaatgg gagaagctag tgatgatgaa atgagtaagc ttcttgaaga aacagcagag
     6301 atacaaacta tacttgaaaa tagtggtttt tatatgatag atgcaaagat acaagaagtt
     6361 gcaaatggtc ttggtcttgg agaaattggt cttgataaag atgtaactga cttaagtgga
     6421 gggcaaagaa caaaagtact tcttactaaa cttctacttg aaaatccaac tattcttata
     6481 ttggatgagc ctacaaacta tttagacgaa gagcatataa catggcttac taagtacctt
     6541 caagagtatg agaatagttt tgtcttagtt tctcatgata ttgaatttat aaataataca
     6601 tgtaatgtaa tatatcatat ggaaaatgga gagttaaata gatataaagg aaattatgat
     6661 gaatttgtaa gacttaatga tataaagaaa cgtcaagaag aacaagctta tgataaacaa
     6721 gttgaagaaa gaaaaagact agaggatttt gtagctagaa ataaagctag agtagcaact
     6781 agaggaatgg ctaacagtag acaaaagcaa cttgataaga tggaaatatt agaaagacca
     6841 aaagaaaaaa taaaacctac ttttgctttt aaagatgcta gagcagctag taaaataatt
     6901 tttgaaacag agaatttagt tttagggtat gatgaagcat tgacaaaacc acttaatttc
     6961 catttagaaa gaggaaaaaa gattgcctta aaaggaatga atggtattgg gaaatctact
     7021 ctattaaaaa ctttacttgg aataataaaa ccatttgaag gaaatgttaa attaggtgac
     7081 tatttggaag ttggatattt tgaacaagag agttcaaggg aaaatagtaa tacacctatg
     7141 gatgaagttt ggagtgaatt tccagggctt acaaactttg aagttagaca ggctcttgca
     7201 aaatgtggac ttacaaatga acatataacg agtcaaatga gagtattaag tggtggagaa
     7261 gctgctaagg ttagactttg caaagtaatg ttaaaaaata taaatttctt agtattagat
     7321 gagcctacaa atcatttaga tgttgaggca aaagatgaat tgaagaaggc tatcaaagag
     7381 tttaagggaa cagttctttt agtatgccat gagccagaat tttattcaga aattgttgat
     7441 gatgtatgga atatagaaga ttttaccact aaaatcgtgt agtgatttaa cttattgctg
     7501 gggggatttc atgaaaaagt ttctaaatgt acttttttca gtttgtatta gtattgttat
     7561 aatagtaggt gttattaatt ttactgttgg atttaaacaa ctttattatt ttgacattga
     7621 ttacttaaat atatcagagt tatctggttt atctgaagat gatataaaat tgaactacga
     7681 ttatctaatt gattataact taaataagaa tgtgtctgag ttcaagttac caacattaaa
     7741 atcttctcca caagggaaga tacattttga agaagtcagg aatatatttc aaaatataaa
     7801 taaattagct aaattattat tggtagtttt tttagtagga attatattga gtgtaaaaaa
     7861 taaaaatata aaaatcttga aaactacatc aataacactt ataattatgc cattattatt
     7921 aacagttcca attttattaa attttgaaaa atcatttatt atttttcata aattattatt
     7981 tagaaatgat tattggatat ttaatccaaa tttagaccca gttataaata tattgccaga
     8041 ggaatttttt tttcactcag gaatgatgat tttaatatta attttgttag caagtatctt
     8101 actatttgta atgtatagat tatataaatc tttcaaaata aaataagata gcaaaaacga
     8161 attatattaa aggttataca ataaaaatag ctatgtaata atatttaaac taagagtagt
     8221 cgataaatat ttatgcatag ctatttctaa tagaaattac tttttactag tgattttaac
     8281 taaatcttga aatttgccca taatgtaatt gtaattatct tttttgtgag gtaacatgca
     8341 actactgcaa tctttgatac ctttatctgt atacttaaag tttccaccac agttttctcc
     8401 taaagcatac aaaggacaat agcaaaatag acagttaaac tcttctggtt tattagtttt
     8461 atgacaaggg aaaaattcgc aatctttgtg attaaaaaac ttataatttt cgcccatatt
     8521 ttcctcctaa ttaaataaaa tttaaatttt ttatactata taagattttg gtgataatat
     8581 aattatacta aataatttta tgaatagtcg ataatatagt attattaatc atagtattaa
     8641 tggtataatt agtcaacaga aaaataatgt aaaaattatg taagtgtatt ttgtaattag
     8701 aatatgtttt ataacaaaaa atgaggtgat taagtgaaag aaattcaaga aaaagcactt
     8761 cttgtaggtc tgaatttgac tacaatagtg aaaaaaaatg atgatataga cactagtgaa
     8821 tctatggaag aattaaaaga gctaacaaaa gctgctgggg cagaagttgt aggtagctta
     8881 attcaaaata aacattctgt agatgcagct tattatatag gaaaaggtaa agtagaagaa
     8941 ataagagcct atagtgactc tttagatgct actttagtaa tttttaatga tgaattatct
     9001 ggtgctcaaa tcagaaatat agagaatgtt gttggaagaa aagtaataga tagaactact
     9061 ttaattttag atatatttgc tcaaagagca cttagtaaag aaggtaaatt acaagttgaa
     9121 ttagcacaat taaaatatag attgccacga ctttatggaa tgggtggtga gatgagtaga
     9181 acaggtgcag ggattggtac tagaggtcct ggagaacaaa aactagaaat agataagaga
     9241 catatactta ataaagcagc agacataagg cgtgaactta aagaagtaaa aaagaatagg
     9301 gagacacaga gagttaagcg tttaaagtca aatataccga ttgtagcact tgttgggtat
     9361 acaaatgcag gaaaatctac tcttttgaac gaattaataa agacacacaa ggattatgaa
     9421 caagaaaaag aagtttttgt aaaagatatg ctttttgcaa ctttggatgt aactctaaga
     9481 aaggctcttt tgccgaataa aaaagaattt ttagtagtag atactgttgg atttgtaagt
     9541 aaacttcccc atgatttagt agaggcgttt aaagcaacat tggaagaagt acagtatgca
     9601 gatttaattt tacatgtaat tgatgcgaca aatactagtt atgaattgca aaaaagtacg
     9661 actgaaggtg tattaaaaga acttggtgta aatgataaaa aacatatact tgtatataat
     9721 aaagtggata agctagaatt ggatatatat cctaaaagtc aagaagatat tgtgtatatt
     9781 tctgcaaaac aaggcataaa tatggataag ctattaaata tgatagaaat tgctttaatg
     9841 gaaaatactt attcagtaag cttgatgtta ccttatgaga gaggtgatat atttagtaga
     9901 ataaaagata aatataatgt ggagaatttt gagtatgggg aaaatggcat aacgctagat
     9961 gtaaacttcg atgaagaaga ttttaatatc tatagagagt acatactaga aaaataggtt
    10021 gaatatggat ataaattggg aaaatataga taatcttgaa gattatttta taacctatct
    10081 tctttataaa gaatctaaaa cagtatctca aattagtaaa attagaaata tttcaagtac
    10141 tgaagcaggt gagcaactta tacaagcaaa attaaaaata aaggaaatgc aaaaagatga
    10201 ttttgaggca tctaaggata ttttagataa atttttagaa ctagataaaa ttaagagact
    10261 tgattttatg gatagcttag atgacgaaaa aatggtatac tttaagagaa aggttttcaa
    10321 aagaatcctt gtggaaaaaa atgctgaaga tttaattgtt ttaatttggg cgacaggtga
    10381 gctaaaagat gatagattct taaagttgct tcatcagctc acaaaccaca gacactcaga
    10441 tattagaaga ataacttatt cagcaatcag aaagattgaa tcaccaagta gtagagaagt
    10501 actgcaaaaa ggtctctacg ataaaaatgc acaaactaga cagtattgtg caaaggctct
    10561 ttcaaaacta ggggatgaaa acagtttaaa gattttacag cagttgaaag acaagaataa
    10621 gaattttgaa aaagaatatg tgcttagagc ttatgacgaa gccattaagt cattggaaaa
    10681 tgcaaaaaat ttgaaaaagt aattttttat taaagcaatt tgtttactta atgatgtatt
    10741 tctagagttt aacaaggtaa taaataaatt aatgggaggg gtttcaaatg atagtaagac
    10801 gttgtgcagg tggagtagtg ttttatgcta ataaagtact tattgtaaaa aatgataggg
    10861 gagaatggac acttccaaaa ggaaagatac ttggaggagg acttccatat gagagtgctg
    10921 ttcaaagagt taaagtagaa actggcatag atgctaaaat gatagatgtg gctggcgata
    10981 ctatgtatga atttttctca agaagtagac aacaagaagt ttgtaatgca ataatgtggt
    11041 atgttatgga agcttgtaac actaattgtg tacttgctcc tgaatttcaa gaaggtggat
    11101 tttataaagt aaaggatgct ttagatatgt tatcacatca taaagagcaa gctttagtag
    11161 aagtatctta taaaaagttt aaggaattaa agaaattagt ttcagagggc gatgatgttc
    11221 cagcaaatta attgtgaatt tagaggattc tgaggaaggg atagcccctt ccttttttaa
    11281 ttgaagcagt tttaagcgta aattatatag tctctttaaa ttatgattta tcaatttaga
    11341 gctttagtag tttatattta aaatcagtaa gatatattta aaataaaaat taaaaagtat
    11401 acaattttat tatataattg tcttatgata ttgattaaag aagtattaaa agtccattta
    11461 tttttaaata gaataatttt atagatatat aatttgatgt gtatattaga aaatgattaa
    11521 aataggagga aatacaatga gcaattacag gacattacat gaatttggaa cagatgaaat
    11581 aactattgaa aagtctgttt ttattggata tgctaagcct ataaagagtg aagaagaagc
    11641 attagagttt ataaatgaaa taaagaaaaa gcataaagat gcaactcaca atgtgtgggc
    11701 ttatactgta ggtaaaaata tgaatataca aagatatagt gatgatggag aaccacaagg
    11761 aacagctgga atacctacat tagaggttat aaaaaaagaa gatttgagag atgtagtggt
    11821 tgttgttact aggtattttg gaggaacaaa attaggtgca ggcggtctag ttagagctta
    11881 tacaaaaggt gctaaattgg gacttgaagc aggtaagata atttataagg taatgtatca
    11941 agaagttaag gttaagatag actatactca acttggaaaa gtgcaaaatg agttaatgaa
    12001 tttggggtat tttataaaag atactgtata tgaggataat gttgagatag tagtgtattc
    12061 aagattagaa gatgtagaga aattatcaga aaaaatgatt gatataacaa atggaacagg
    12121 aaaaataatt ttaggagagg aattttattt gtctgaacaa aatggagaaa ttttaatata
    12181 atctaaaagg ttattagaat agttaatacc tcaaatagcc aattagtatt tttaagtgaa
    12241 aagccattaa attgatttaa tctaaatcaa tttaatggct ttttatcgga ttttgcacag
    12301 aatccttttt ttacttcaaa taaaccgact aaaagtaaaa atatcccaaa tatttttttt
    12361 aatatatctg aagacagata attagctaat agtgaaccaa atacagctcc taaaacccca
    12421 aacacagcta taggtataac caatttaaaa attacatttt tattttttat atgtatagca
    12481 agtgctataa gtgtcatagg gatagatgaa agtaaattta cgctttgtgc tattttagtg
    12541 tctatgccag caagtaaaac gagtgcaggt ataaggattg ttcctccacc cattcccatt
    12601 cctccaataa ttcctgcaaa aaatccaatt agagcaaata acattaaaac accatcctta
    12661 atgctgcaat tatcataatt attccaaaag aaattctaag aaactttcca gtaaccttat
    12721 ttagtaattt agctcctata ataccaccaa gaatacttcc aactgcaact ttaattgtta
    12781 agttaacatc ataagtacct ttagatacat ataaaacaga acttgctgtc gttaagaata
    12841 ttattataga aagagcagtt gcatgagatt tatgttcttc taccttaacg atgtcattta
    12901 atattggaac taaaagagta cctcctccag aaccaaaaac tccatttata aatcctgtaa
    12961 aaactccaat tatcgtattt tttaagttaa aatcaaagta ttttttcttt aaatcatcag
    13021 tttttttcat aaaaatcacc ttctgaaata gttttaccaa aataggcaaa ttatatttat
    13081 ataaaataag attaaatata atctttcatg tttgtttaat tttgcataaa aaaaaacata
    13141 ttaaaacaac atattaatat atggtataat atattaaaac aaagtagcaa atttgagagg
    13201 agataacaat gtcaaatata aaaatacaaa tagacaaaac tgtagaatgg cttataaata
    13261 aggttaatga ggcaaatgca aaaggattaa ttgttggtgt atctggagga attgattcgg
    13321 cagtagttgc taatttaatt aaaaaggcat ttccagaaaa ctctatggga gttataatga
    13381 gcataaaaag taatcctcaa gatagagaag atgcacttaa ggttatagag ggatgtgata
    13441 tagaatacct tgatttagac cttatagaac cacaaagtgc tatattagac atggtagtag
    13501 gaaatttaaa agataaacat ttatatagag cagaatattt aaagatgaca gatgcgaact
    13561 taagagcaag agtaagaatg agtacaattt atacaattgc taacaatcta ggatatttag
    13621 ttgttggtac agacaatgct gcagaaatac acacaggata ttttactaaa tttggtgatg
    13681 gtggagttga tattttacct attgcaaatt taactaaagg agaagtatat gaatgggcaa
    13741 aagagcttgg tgttcatgaa gatttaataa acaaagctcc ttcagcaggt ctttgggaag
    13801 gtcaaacaga tgaagatgaa atgggaacta cttacaatat gatagatgct gtgttagaag
    13861 gtagattgga tgaagttcct aaaagagacc aagagataat agaaagactt catagattaa
    13921 gtgaacacaa gagaaaaacg cctgcacaac ctcctaagtt ctaatttact atttataaga
    13981 tttgtgataa aatttacaag tgatgaaaat tagaataatt aattgtacgt attaaggagt
    14041 ggaaatatgg gacgtatagg taatataatt aatagaaaag gtaaacaaga tgctcaaaga
    14101 gcaaagatat ttactaaaca tgctagagca atagcagttg cagctaaaga aggtggagca
    14161 gacccagagt acaatgcagc gttaaaaaca gctatagaaa aagctaaggc agataatatg
    14221 ccaaatgata atatagatag agctatcgct aaaggtgctg gagcaggcgc tggagaagac
    14281 tatgaaacta tagtttatga aggatatgga cctggtggag ttgctgttat agtagaaact
    14341 ttaactgaca acaaaaacag aactgctggt aacgtaagat actattttga caaaaacgga
    14401 ggaaacttag gaactagtgg atgtgtgtct tttatgtttg ataaaaaagg acaaatatta
    14461 gttggtttag gagatggagt ttcagaagaa gaattgatgg atgttgcatt agaagcagga
    14521 gctgaagatt tcataacaga agaagatggt tatgaaataa taactacacc agaagatttt
    14581 tctagtgttc gtgatgagtt aaaagctaaa ggatatgagt ttatatctgc tgatgtgaag
    14641 atgatacctc aaactacgac tgtattgact gaagaatctc atttaaaaat gatgaataaa
    14701 ttagttgata tgcttgaaga agatgatgat gttcaagata tatatcataa ctgggaagta
    14761 gaataaatag tataagcata ttgaaattta taagcattga atcaatttta acatgtgata
    14821 aattttatag aataagaaat tactaaaata gacatacgca cctctaacct atatttgcat
    14881 aataatatgt aagtataggt aaggggtgtt tttatattta taggttaaga aatttaaagt
    14941 aaattttgag ctggacttga ttgtctataa ataattgatg ggtatataac ttgttgctga
    15001 ataccattta tacgcccagt tactgtatca ataatcatcc taagactacg ttctgctgtc
    15061 tcttccattt ttaaatctat aactgtcaaa ggaggaatac ttcttgccat tagtcgtgaa
    15121 ggtccattac ttgctgcaaa tatttgaata tcctctccaa ttacaattcc agattcatga
    15181 aatgcattca tcataccaag agctacaaca tcatgattac aaaaaattac tttttttagt
    15241 gaattttttg caagcatttt ttgagcaata tcatatccac tatctatttt attagaacaa
    15301 taatatatag aatctgatag atgtattcca tgttctttac atgtttttaa aaaagattta
    15361 ccccttaaag tcatacatgt aaaggaagtt gggttgaata caacagcaat atcattttta
    15421 ccattttgaa tagcatgtaa agctgctata cgaccagttt cctcattatc aatagataca
    15481 cttgaaaaac caggtatttc acgatttaca acaactacag gaattttagg tttatttttt
    15541 actagatatt ctatatcatc agcattgata cctgttaaaa caattccatc ataataatta
    15601 tttgcaaaaa agtattcatc atcacataga tgaccaactt tgtaaggtcg tatgatgata
    15661 tttatgttta aatgttctaa agaaattatg tggtttattg cttgaagtat attggttgat
    15721 gccaactcaa atccctcatc ctgccaataa aaagctattt taatattatt atgtttaata
    15781 ggagtagagc gtttatatcc aagcttatca gctgaattta atataagctc ttgtgtatgt
    15841 agcggaatcc tgcgttcatt tcctttacca cttaagacgt acgagacagt tgctgaagaa
    15901 agaccacagt cttttgcaat atctttgatt gttgccatga taaaatcctc cttaaatagt
    15961 tgcttaaatt tgcttatacc aataatctta acatatattc aactaaagaa caatattcta
    16021 caaggtgcat attttacagg attagaataa ataaatttaa aaaaacttct tacttatgtt
    16081 gacataattt agtttatagg attataatat gcttaaataa gcttattatt aactcaaatt
    16141 aagcaaagtt aagcaggaac atgcaatgct agcttgcaat gtgactgtaa agggggaaaa
    16201 ggtatgagta aggtaaatat atttgaagtt ggtcctagag atggatttca aaacctgaaa
    16261 gagtttttag aaactgataa aaagcttaag attattgatg gtcttattgc ttcagggatt
    16321 aaacaacttg aaattagttc atttgtaagc ccaaaagcaa tacctcagat gaaagatgca
    16381 aaagaagtag caacttattg tgtagaaaaa tatcctgatg tgaaacttta tgcattagtt
    16441 ccaaatttat atggtgctaa agttgcatgg gagtgtggta taagagatat atcctatgtt
    16501 atatctttga gtgaaactca taataaaaaa aatataaatc gtacccatga agagtctatt
    16561 gatgagctta aaaaaataat gaatacttat ccagacatga atatatgtat tggaatggct
    16621 actgtatttg ggtgtccttt tgaaggttta ccaaaaattg aagatgccat aagatttgct
    16681 aaacgccttt gggaaaacgg tatcagggag ataaatctag cagatacaat agggattgct
    16741 gaccctaagc aagtaagaga aactattagt gcattagttg aagctttacc agagtgcaga
    16801 tggcaggtac atattcatga tactagaaat atgggaatgg ttaatactct tgtggctatt
    16861 gaatctggaa ttactactgt tcagtctaca cttggaggat taggaggatg cccatttgct
    16921 cctggagcat ctggcaatac tgcaactgaa gatttagtat atatgcttga acgtatgggg
    16981 tatgatacag gagttgattt tgttaaactt cttgaattat caaagtatca gaagagtttt
    17041 gtaaatggag tatatagtgg tcatcatgta aatataaagt ctgatagttg taattgttag
    17101 ttctattgat taatcgatta aaaaaatatg ttgattaaaa aaatatgctg attggtaaaa
    17161 tagatttatt gataaaaaag ataaattata aaatacatta tctaataaaa caaataaaaa
    17221 aattgagggg gattagtatg gatattatag ctttactttt atttttagga gttattatta
    17281 ttgcatttgt acgtaagaat aatgcaggta ttttggctct agctattggt gtcatagctg
    17341 ttagaatttt tggaatggat gataaagaac tttatggagc tataagcaac tcaatgttta
    17401 ctacacttgt tggtataaca ctactctttg caatagtgaa ctcaacagga gcattaaagc
    17461 ttgttgcaga aaaaattgta gctgcttctg gtaaacgtgt ttggcttata cctatagcag
    17521 tttttatagc aggatttgtt gttgctggtg ttggacctgg ggcaattcca gcacttgcaa
    17581 ttatcccagc aatggctgtt cctgtagcca taacggttgg ttataatcct gtaatgcttg
    17641 cacttatagg tgaatgtgga ttaatggcag gtcgtatgac tcctattact ccagaaggtc
    17701 aaattataac aaccgttgca gaaggggttg gaattgaaaa tgttatgcct actatcttag
    17761 cctgtcaaac tctttctaca attgtatttt caatagtatt gtttataatt ttcaaaggat
    17821 ataaacttaa aaaacctata aatgttatag atagtaagca aatagaaaaa tttaatataa
    17881 agcagataat ttctctaata agcatagtag ttatgattgc ttttatcata atttttgata
    17941 tgaatgttgg gcttgcagct tttgcagttt cagctgtact tatttttttc aatattgctg
    18001 atgaaggaga atgtatcaaa tcaattccat ggagcacgat agtaatggtt cttggagtag
    18061 gtgcaatgat gacaatcgta gatgcagcag gaggtattga cttgatgagt aatgcattat
    18121 catcactgat gaatagtaaa acagctactc caattatgag tatttcagca ggacttatgt
    18181 ctatggttag ttctgcttta gcagtagttt atccaactat gatgcctatg tgtgttgata
    18241 tagctaaggc agttggagga gtagacccac tagcacttat tgctgcagtc ggtgttggag
    18301 gttctcttgc tggtgtaagc ccactttcta ctggtggggc attgatttta gcagctatgg
    18361 gttcaagtaa gaaagacttt aataaggaag aacaaaataa ggtttttgta cagcttttca
    18421 ttatgagtgc agttggctta ttggttattg cagtagtatc aatattatca tttaatgcaa
    18481 taacacattt aatgaactaa ttataataac tgaaaataat tcattaaatt taatttttaa
    18541 tattaatcaa tataatataa tttggagggg aagttatgaa aaaaggagca ttaagcaata
    18601 taaaggtact tgaccttaca agagttcttg caggtccata ttgtacaatg atgttggcgg
    18661 attttggagc tgatgttata aaaatagaga tgccaagaaa aggtgatgat acaagaggtt
    18721 ttggaccttt tgtaaatgga gagagtttat actatgcaaa tataaataga aataaaaaag
    18781 gtatcactct aaaccttaaa tcagaagaag gaaaaaatat atttttagaa atggtaaaac
    18841 atgctgatgt tgtagtagaa aattacagac caggtgtaat ggaaaagtta ggtctgggtt
    18901 atgatgagtt ggctaaagtt aacaatcaaa taatttatgg agctgtatca ggatttggat
    18961 gttatggacc atattcagaa cgtccaggtt atgatattat tgcacaggca atgggtggtc
    19021 ttatgagtat aacagggcaa gaaggaggag aaccaacgag agttggtaat gctatgggtg
    19081 atgtactagg tggaatgaat ttaactattg gtatactcac agcactcaac gctagaaaaa
    19141 taataggaaa aggacaaaga gtagatgttt ccctcgttga ttctgttgta tcgtctctcg
    19201 aaactggtat acagagatac tttgattcag gacaacctga acttatgggt aatagatatg
    19261 cttcagccta tccttatgac tcttttaagg caagtgatgg aagttttgta ataggctgtg
    19321 gtaatgacaa actttttgaa aagttatgta aaaaagttct ttttagagaa gaccttttaa
    19381 tagatgagag atttaaaaca aatcttaagc gttgtgaaca ttacaaggct cttaaaccag
    19441 aaatagaaaa atggtctgtt aagcatacaa taaaagaagc agttgactta atatcagagg
    19501 ctggagttcc tgctgctcct atctataatc ttgattgtgt tacaacagat gaacatatag
    19561 caaaagcaag agaaatgatt gtagatatta gtcatcctat tataggaaat atgaaagtca
    19621 atggaaatcc agttaagttg atgacaacaa aagctaaaat tgatatgcca gcaccatctc
    19681 taggggaaag taacgaggag atttataatg gttggcttgg ttttgatagt gataaaataa
    19741 aagatttaaa agaaaatgga gttatttgat taaaaaatag ctaaacacac ttgtgacttt
    19801 agtcatggga ggttcagtta gaataatatc aaaaaatatt aaatcaatac tgtaaatcaa
    19861 atatagaatt gtcagaagca tttaagatgg gaaaagctac ttagacattg agtctttgtg
    19921 gcttttccta ttttcattaa gaactttata ttatcagaat agatatgtac taaactaaag
    19981 tattaacaat ttaaattaat agaaaataaa ctacctaatt atgttgaata aagactactt
    20041 tagtgaaaat aaacttatag agatgctatt taaattattt taatggaaat atcaaaaatg
    20101 agactgcatt ctcaaaaatg agactgcgtt ttttaagtat tttctcgaaa atgagacaaa
    20161 aatattgttt tatgagtttt attgaagaaa aattcttctg tgaattacaa tttaatcaat
    20221 tttaaagttg aaaattatta aaaatttagt gaaatttatg tatatttcgt ttattttatt
    20281 aaaaataaca attttttact aaaaataaag aacttcaatg gtgattggca tagtacttgc
    20341 tattttatat taacaagaaa tgtagaaaaa ataacaatgt ataatggggg gaatatgatg
    20401 gaatctgtaa tggaaaattt gaacaatctt aaggtggagg ttaaggacaa agtctgtgtt
    20461 attactataa atagacctaa agctttaaat gctcttaata gtgacactct tagggaacta
    20521 tcacaagtta ttgatgtagt atcagaaaat gaggcaatat taggagttat tattactgga
    20581 gaaggtaaag tttttgtagc cggtgctgat atacgccaga tgcaaaacta taaaagtgag
    20641 gaaggcagaa aatatgcagg ttatgctcag ggaatttttg ataaaattga agctcttgag
    20701 aaaacagtaa tagcagcagt taatggatat gcattaggtg gtggatgtga acttgctatg
    20761 agttgtgata ttagaattgc atcagaaaag gctatatttg gacaacctga agttaattta
    20821 ggagttattc catgttttgg tggaactcaa agattatcaa gacttgttgg aactggaata
    20881 gctaaagagt taatttttac ggggagacaa gtaaatgcag aagaagctaa atctattggg
    20941 cttattaata aagtggttcc aagtgattta cttttagaag agtctatgaa gatgatgaac
    21001 caaatagttg aaaaagcgcc aatagcaata agatatgcaa aagttgttat taacaaaggg
    21061 atagatatgg atttaaagaa tgctcttgaa ctagagaaag atattgcagg tttaactttt
    21121 gctacaagag ataagcaaga aggaatgaat gcatttatag aaaagagaaa gccagttttt
    21181 gaaaataagt agctattata actaaattgg aacaatgtag aatatattca aaatctaaat
    21241 ttcgtgaaaa aatacatata gtttaatttt aaaaggagtt aatttatgaa tacgggagta
    21301 attataagtt tagtagggat tatcatagct ctatctcttc tagttgtaat ggttatgaag
    21361 ggaataaata tttttattat agcaattgta tgttcatcat tagttgctat aacaggaagc
    21421 ctaaatgtgt atgatgcact taaagtggat tatatgacag gatttgttgg atttcttcag
    21481 gcaaatttct ttattttcct aacagggaca ttaatgggaa aaataatgga gattactggt
    21541 ggagcaaaat ctattgctaa gatgattgta agatggattg gtaaggataa agcactactt
    21601 tctattccaa tagcttgtgg aatattagcc tatggtggag taagtgtttt cgttgtaagt
    21661 tttgcagtgt ttccgatagc tttagaaatt tttaaagaag ctgatttgcc acgaagattt
    21721 ataccagcag ctttgacttt tggatgctca acttttgcta tggttgcacc aggggcacca
    21781 caaattcaga atattgttcc agcatcaaca ttagggacag atattatggc cggagcagta
    21841 aatggtttta tatcatgtgc agtaatgttt atagttggaa gtaccatttt gtacaaaatg
    21901 gtttcaaaag aaaaagccaa tggtggtcat tttatagcac atgaatcaga tatatttgat
    21961 gaagcagaag caactaattc taagagagaa aatggtccta atggtgtaat tgccttaatt
    22021 ccattgatag tgtcaatttt aataattaat gtaaaagtta atggaaaagc gatagtacca
    22081 attgaggtgg gagtatttat tggagcttta ttagtatatt tattgttaaa taaatatcaa
    22141 gataatacta aaatagttgg acatgttggt gatgcatgta aaactacagt agtagcaata
    22201 tgtaatactt gtgctgtagt tgcatttggt tcagtagtaa aatcagcagt tggttttgac
    22261 ttcatagtta atgccatgac taatattcct ggtcctccta ttgcaggggc tgcagttgga
    22321 actacagtta ttgcaggtat ttgtgggtca gcttcaggtg gactaggaat tgcagctcca
    22381 cttcttggac cagtattttt agccaagggt gtttccgctg cagcattaac taggactatg
    22441 gcaatttcat cagcagcatt agattcactt ccacacaatg gatatattgt tactgtaaca
    22501 aatggtctgt gtaaagaaac acataaggat gcctatatgc caatattctg ggtaactgtt
    22561 ttaactccgt ttattggaac catagtagca gtcctactgt ttacaatgtt cccgggattg
    22621 ccataagaga aaagataaaa ggtataaatt atattttgat attataaaat caattttcaa
    22681 aatatataca ataaatttca tgttttaata ctataaatat gtatttaaaa taacaaattg
    22741 accatataag gaggaattga aagtgttaaa taaaccatta gagggagtta aggttattga
    22801 cctaacgtat tttgtagcag gtccagggac ttctaaaata ttagctgatt ggggtgctga
    22861 cgttattaag gtagagccaa gctttggaga cccaggaaga aagacagggg caacaatgac
    22921 aatgccaata gatgattata ataatccttt ttacagcaca tataattcaa ataaaagagg
    22981 tttgtctata aatcttaaga gtgaaactgg aattgaaatt atggataagc ttttaagtga
    23041 agcaaacgta tttgtttcaa gttatagaac aggagcatta aaaagactag gtcttgatta
    23101 tgaatcatta agtaaaaagc atccacacct tatctggggt cagataaatg gttttggcga
    23161 ttttggacct gctaaggata atgcaggatt tgatacagtt gccttttggg caagaagtgg
    23221 ggctatgctt gatatagcag aaaaagatac aagtccaata aatccaccta tagcctttgg
    23281 agatgcaaca acttcttgta gtttatctgg aggaatatgt gcagctttgt accagcaagc
    23341 taagactgga aaaggacaaa aagtaatggc atctttattt gggcaagcaa tatggaatgc
    23401 atcatcttta ttagcatcta cacagtttag tgatgagtat ccaaaaacta gaaaaaatgc
    23461 tatttcacca gtaataaatt cttatcgttg taaggatgga aagtggatat tcttaagtat
    23521 tttagagcat gaaagatatt ttgaggcact ttgtagatta tttggaagag aagacttaat
    23581 aaaagaagag aaatttgcat cttcagtaga aagtaagaaa aatgctacag aacttattaa
    23641 tattttggat ggtgaatttg caaagtttac tcaaaatgag atggttgaaa aacttactgc
    23701 tgctgatata gctcatgaaa aaattcaaca tgttaatgat gtagtgactg atgaacaggc
    23761 tattgctaat aactatatat atgagcatac aagtaaaaat ggaaataaga caatgcttgc
    23821 atccactcca gttaaatttg gaaatattga agttaacatg acttgtgatg ctccacttat
    23881 aggagaacat tcagatgaga tattgagaga acttggatac agtgattctg atatagaagc
    23941 tctaattgaa tctggaattg taacaatgaa taaagaagca tgtgaaatat gttaataaac
    24001 atgtgaagta tgttaataaa taggagggaa ttttatggat tttagattaa cagaagcaca
    24061 attaatgctt caaagagtag caaaagaatt tgcagagaat gaaatagcac caatagctgc
    24121 tgaaacagat aaaacaggta tttttccaag ggagcttttt agcaaaatgg ctaaaatagg
    24181 atttaatggc attggaacac ctgtagagta tagtggttct ggagggacag atatagaaaa
    24241 ggtaattgtt gttactgaga ttgccaaaaa atgtgcagca tctgcagcaa tattatcaat
    24301 acacacaata tatgctcaag ctattttgaa atttggtact gaggaacaaa agaaaaaata
    24361 ccttccaatg atggctgaag gtgggtgtgt aggtgctttc gccttaactg aacctaatgc
    24421 tggttcagat gctgcaagag ctgcaacaac tgcaattatt gatgaagaaa cggatgaata
    24481 tgttttaaat ggaactaagt gttttatttc tggtggaggt caagcagaat cattaataat
    24541 atttgcactg acagacccat caaagggaat aaagggaatg tctgctatca ttgtcgacaa
    24601 aggtactcca ggtttttcaa taggaaaaat tgaagaaaaa atgggtattc atggttcaga
    24661 aactgcagag ttaatatttg ataactgtag agttccaaag tctaacttat taggaaaaga
    24721 aggcaaagga tttaatatag ctatgacttg tttagatgga gcaagaattg gaattggagc
    24781 tcaagctgta ggaattgctg aaggggcttt agaagaaagt atcaaatatt ctaaagaaag
    24841 agtccagttt ggcaagccaa tttcagcgtt gcaaggtatt caatggtata tagcagatat
    24901 ggcgacaatg gtggaatcag caaaattatt agtatattat gctgcagatt tgaaagctag
    24961 aggagaaaaa cacactaaag aagctgctat ggcaaaatac aatgcgtcaa gtactgcaag
    25021 agaggttaca aatctagccc ttcaaatcca tggtggatat ggatatatga aggattatcc
    25081 attagagaga atgtacagag atgccaaaat aacagaaatt tacgaaggta cttcagaaat
    25141 acacaaagtt gttatttcaa gagcagtact aggataggag gaaaagaatg aatatagttg
    25201 tttgcttaaa gcaagtttca gatactaatg aagttaaaat aaataaagag acaggtactc
    25261 taataagaga tggtgtacca agtataatca atccagatga tagaaatgct ttagaagaag
    25321 ctctaaaaat gaaagatgaa ctaggagcag tgattaaggt tataagcatg ggacctcctc
    25381 aagctaaaag tgctttaaaa gaagctttgg caatgggagc tgatgaagct tatttaatct
    25441 cagatagagc ttttggtggt tcagatactt gggctacatc tacaattatt gctgctgcta
    25501 tagaaaaggt tggaaagtat gatgtaatat tctgcggaag acaagctata gatggagata
    25561 cagctcaggt tggaccagag gttgcagaat ttttagggat accacaagtt acttatgcaa
    25621 aagaagtaaa ggttcaagat gacaaattac tagtaactcg ttatacagag acaggggatt
    25681 atttaataga agcaaagatg ccagttttat taactgctat aaaagagtta aacaatccaa
    25741 gatatccaag tgtaaaagga atcttagaag cttataataa tggagatgcg aagattactg
    25801 tattaacact tgcagattta gatgttgata caactcaaat tggattaaag ggttcaccta
    25861 caaatgttta taagtctttt gcaccagtta aagacaagca taatgaaata atagaaggta
    25921 taaataaaaa agaaaaagct gagaaactaa tagaaatact attcgatttg aaactagtat
    25981 aggagtgtta agatgatgag agcaaaagtt aatcaaggta taaatttaaa tgattataat
    26041 ggtgtttggg taatagggga gcaaagggaa ggcaaaatta atcctgttac gatagaactt
    26101 attggtgaag gaagaaagct tgctgaccaa ttaggaaaag agcttgaagt tgtgatagct
    26161 ggatatgaag tagagaaaga agtgaaggaa ttacttcact atagtgttga taaagtatat
    26221 tacatcaatg accctcttct taaagatttc actactgatg gatatgcaat ttcaattgca
    26281 aatttaatcg aaagaaaaaa gccagaggtt gtattggttg gtgctacttc tataggaaga
    26341 gatatagcgc ctagaattgc aggtaaggtt ggaacaggtc taactgctga ctgtacaaaa
    26401 cttgaaatag attcaacaga taataagtta ttacaaacaa gaccagcatt tggtggaaat
    26461 ttaatggcca ctattgtttg tccaaaaaat agaccacaga tgtcaacagt tcgtccagga
    26521 gttatggcaa aagctgtaag aaacgaatca gagactggaa ttttagaagt tgttactcca
    26581 gaacttactg aaaaaatgat tagaactaga ttagtagagg tacttccaca agaaaagaaa
    26641 tctgtaaatc taactgatgc tagaataata gtatcaggag gaagaggatt aaaaagagca
    26701 gaaggatttg agcttataaa agaattggct gataaattgg gggcagagat tggtgcttca
    26761 agagcagcag tagattcagg gtggatagaa cattctcatc aagtgggaca aacaggaact
    26821 actgttagac cagaactata cattgcatgt ggaatatctg gagcaataca acacttagca
    26881 ggtatgagtg attctaaata tatagttgct ataaataaag atgcaaaagc ccctattttt
    26941 agtatatgtg actatggaat agtaggagat ttatatgaaa ttatacctga aatgatagaa
    27001 tcattaaata ggtaactttt agaaaacatt gaatatgtag aatgataagt cttataatat
    27061 tgtattgtaa gacttattat ttttgctgaa ggttatagtg gggagatgaa acaatgaaag
    27121 agcagtggta taaggatata tttgcaagaa tattatctat gactgatgat ggttttattg
    27181 ttgtaaatac aagtggagta ataatagata ttaatgataa atattgtgac tttttaggaa
    27241 aagaaagaaa agatataata ggacaaaata tacaaagtat tataccaaat acaaaaatgc
    27301 tagatgttat gaaagataag tactgtgaag aaggagctat acatcattat tcaggtggaa
    27361 atacaaaaga aaaaagtgta atagtaagta ggtcttatgt agaaaatgac aatggagaag
    27421 tagttgcagg agtagctcaa gttaaattta gattgcaatc atttgatgta gctaaaaaat
    27481 taatgtcaga atatatggag ctccaatatt ataaagagca gtttaaggat aactgcggtt
    27541 ttgacaagct cataggtgaa aatagagact tcatagaact taagaaaaca ggtgtgaaag
    27601 cttctaaaac aaactttcca gtacttttaa cgggtgaaac aggcacaggt aaagaagtct
    27661 ttgctagagc aattcacaat aatagcagta ggtcagataa acctatggtt agtataaact
    27721 gcgctgcaat accagaagaa ttattagagt cagagctatt tggttatgac gaaggagctt
    27781 ttacaggagc aaaaaagggt ggtaaaaaag gtaagttttt agttgcaaat aatggtacaa
    27841 tctttttaga cgagataggt gacatgcctt tgaccatgca agcaaaactt ttaagggttc
    27901 ttcaggaaag tgagatagaa ccagtgggag gtcttaaaac tataaagata gatgtaagag
    27961 taatctctgc cacaagaaag aatttaagta aaatggttga agagggatta tttagagaag
    28021 acctatacta tagattaaat gtaataaaca ttcatatgat ggaattgaag gacaggcaag
    28081 atgatatttt attgctagca aattatatat taaacaaatt aaatgttgaa tacaaggaat
    28141 tgaaggtttt aagtgataag gttaaaaatt gttttattaa ctatacttgg ccgggaaata
    28201 taagagaact acaaaatgta ataaaaagtg cctatgctgt aagtgatgat atggtcatta
    28261 tgatgtgtga ccttccatct aagatggata atatcagcag agtagctcaa tgtaatgtgg
    28321 atagcaattg ttcaattcat gaaatggttg agaattatga aaaaagctta attattgatg
    28381 tgttaaggaa gtataattgg aaatgttcta aggcagcaga ggttatggga atacacaaga
    28441 gtcttttata taagaaaata aaaaagtatg aaattgaatt aaataattaa gataacttga
    28501 attaaggcaa tgctaaaaaa agcgccctta ttcaaagcga actgtataaa ctgttttatg
    28561 cagttaaaac gtgtaaaagt agatgtgaag tactaatgtc aatcattagt actttttatt
    28621 gtatttataa ttactatcta tatttcagta tcttttgata tctaagatta ttatgtttaa
    28681 tttaggatat aacaaaaccc tcttagttat tgacagtttt ttatatttta actgtctact
    28741 aagaggggat agtttagttt aaatttagag taaattttat ctagcattta taaaaaatat
    28801 tttgaatagc ttttttgtta tttagtcata attttctact tctttatcaa gttctttgcc
    28861 acaagaatca cacttatata tagcattgta tccataatca tattcatcaa ctattttctt
    28921 ttgtctaaat acaccaccac actcacatag gaaaccaatt tttataagtg taacgataaa
    28981 ttgtgatttt ataaatttta tatcattaca tttatcgtta gtgtaaaatg tataaatata
    29041 agagttatcg cactcatctc ttaattcaaa tctttcaata tatgtgttat tttttaattc
    29101 ctcaaattct tctttagtta aatatgattt ttgttgcaat tcatgtaaac gcttaatttg
    29161 gtccattatt tatatcctcc caataatttt agtattttaa gcttagataa ggaatctaag
    29221 ttttattaaa tttatcccaa ggaattattt aaatcatatt tagttttatt aattacaaca
    29281 tatataaatt acacgaaaat aaaactaatt gtaaaaataa tatcctgtga aaacctaaac
    29341 tactaacccc ttactaaccc gaaaactaaa aaaagaaaat atatccaaat ataagtgata
    29401 tataaataaa gatgttttat ataaatttaa ctttaaatat tctgacaata atatatataa
    29461 atatattata gttaaaatat accacatatt ttgggcattg tatactggaa ttagagtaat
    29521 taatttattt tttaacatac aaatgatttt atgaaaaaaa acaagactca aaaattttta
    29581 tattctttga tagaataaaa ttgagagtaa atttattgaa ttttataaaa tttataaggg
    29641 gtgagtctaa gatatgcatg aagataaaaa tgatatattt gaatcaatag atactgagga
    29701 ttttgataat aaaacagaag aagaatgttt agagctagta agaaaaaatg gattgaattt
    29761 aatatacata aaaaatcaaa cagaagagat atgtctagag gctgttagac aaaattgtaa
    29821 tgcaataaaa tgtgttcaga atcagacaga aaaaatatgt atagaagcag ttaaacaaga
    29881 ttggagaatg ttagaatttg tggaagagtc aacagaagaa atttgcatgt tggctattaa
    29941 ccaagatgga acagcattaa aatatataga aaatcagaca gaggagttat gcttaagagc
    30001 cgttgaaaaa aatggtgcgg ctttggagta tgtaaaagaa caaacagaag aaatatgtat
    30061 agaagcagtt agaaacagcg aatttggatt ggcaagagtg aaaaatcaaa cagaaaaaat
    30121 atgtatggaa gcagttaagc attgtagcta taatctaaaa tgggtagaaa atcaaacaga
    30181 agaaatatgt atggaagcag tgagacaaaa tgggcttgat ttgaaatttg taaaaaatca
    30241 aacagaaaca atctgtttaa gagcagtaag acaaaatgga atggcattag aatttgtaaa
    30301 ggaacagact gttggtatat gcttaaaggc agtaagacaa tatggaatgg cattaaaatt
    30361 tgtaaaagaa caaacagaag aaatttgtac agaagctata aaacaagata aaagagcact
    30421 tagttttgta aaaggagata aggaaaaata caaggctcta tatgataata atgaaccatt
    30481 tgcaaagaga tatgttagaa atgtaataga aaaagaaaac agagcattga ttaaaaaagg
    30541 agaagaaaat gcaaaaatca aaattgcagg aaaactttat gatagaggca tgtcttttga
    30601 agatatatca gatatagttg agattgaaat aagcaagtta aaagtgagtt taggtgtttt
    30661 ttaaagtaat aaatgtaggt gttttttatg ggaaatagtt aataaaaaaa taatcgacta
    30721 gctctttgta ggacagcaaa attagtgata taatttgatg tataataaat tatttttatt
    30781 agataagggg gaattaaagt tgaagattac agtattatac caaacaagaa gtggaaacac
    30841 agaaagggtc gctaagctga tagaagatgg agctaaaaag gtggatggag tagatgtaaa
    30901 gcttatgaga cttgataata ttgatttaga ttatttaaat gaaagtaaag cagtaatatt
    30961 tggaacacct acttatttag caaatacaac ttgggaagta aaaaaatggt ttgatgaaga
    31021 ttcaaaaaaa gttaatttag ctggaaaatt aggagctgtt tttgctacat gtgattatat
    31081 atgtggaggt ccagatgttg cgatacttac tatagtagga catttgatgg ttaaagggat
    31141 gcttgtgtat tctggaggtg gttctttagg aaagccattt atacatttag gacatgtaca
    31201 ttcaattgaa ggtccagagt tacaagatga gaaggctata atatttggtg aaagaattgc
    31261 tactaaggca aaagaactat ttgcttaatt tctatatgca taataatgat tagagtaaat
    31321 ttagggtttt aatggagatt tgaagtaaaa gttataaaat aaaaaatttt ccataaaatt
    31381 actcaagatg aattataata taattataaa taaattatat tattaaaata tttaaaatca
    31441 aacgtcaata gcgagggaag tttatggtat ggcatataga atatgagatt ttttctgcaa
    31501 ttatagttat ttttttaatg gtatactttt ttagaagtaa atttatacct actttacaaa
    31561 acaaaatata ttgtgcactt ttaatattct catttttatt tatactttca aatattttag
    31621 gttcattttg tctaaataat atagacaaaa ttccaatttt tattactttt ttattgaatc
    31681 agatatactt attgttattg ccaataccag cagctcttgt atcattttat gttatggcta
    31741 ttatttatca agatataagg tatatgaaaa aaagattatt atttttatct ataccactta
    31801 taatttgtat aatcttatct attacaaatc cttttacgca tattctattt ggattgtcaa
    31861 aagaaacagg ttatatacgg ggttgtggat atgttgcaac ttttgcatct tttttctttt
    31921 atgcaatata ttcagcattt ttatctttta aatatagaaa agcaatgcat gaatcaaaaa
    31981 tatgggctat tagaggtttt cttatagttt caattgtggc aattatctta caggcaattt
    32041 ttttacagta tcttcttaca ggaactgcat gtgcatgtag tttacttttg acatatcttt
    32101 ctatgcagaa tcgaggtctt attattgatg accttactgg tgtactcaat agacaatctt
    32161 ttattcaaga gctagatttg aatatcaata ctgaacaatc aggatttatt attacaattg
    32221 cgcttgatga ttttaagttt atgaatgaaa cttttggaac aaaaaatgga gatattgcac
    32281 taaaagaagt tggaaaatat ttgattcaga tacatgatgt aaaccatgta tatagaatag
    32341 ggggagatat attttctatt gttgtcaata gtcaattagg tatagaacca gatgatatta
    32401 tcagaaagat agaagaaaga tttaaaaagc cttggctagt agaagagata agttttaatt
    32461 tagcaactag tattgctgtt gtttattacc cagaaaatgc agaaacgaca gaagatgtaa
    32521 ttgttgctat agatttctct atacatgaag caaaacgttc tgagtcaagg cgagttgttt
    32581 atgcagatgc gtctataagt gaaaagataa agaagaaaca tgttattaaa aattgtttaa
    32641 aagaagcatt aaaaaatgat gggtttgaag tgtactacca acctatattt tctaatagca
    32701 ggggcaggtt tacttcagca gaggcattac ttaggctaga acacaaagag ttaggtttta
    32761 tacctcctga tgaatttatt ccaattgcag aacaaacagg attgattaac tcaattggat
    32821 tagtagtctt tgagaaggta tgtagattta tagctagtga tgagtttgaa aatttaaaat
    32881 tggataatat agctgtgaat ctttctgtag tacaatgtat gcaaaaaaac ttagctgatg
    32941 atttacttta tcttatgaat aaatataatg tatcaccaac taaatttaaa cttgaaatta
    33001 ctgagactgt ggctatgggc tcttttaata taattaaaga aacaatggaa agattaattg
    33061 atttaggtgt taagtttgca cttgatgatt ttggaattgc ttattctgga gttactaata
    33121 tgctttcttt accattttca gtaattaagt tagataagag tttgatttgg tctatgaatg
    33181 aagatagtag gcataagctt acagttgaga cgattatagc tcttataaat aaattgaata
    33241 tgaaggctgt agcagaaggt gttgaaacca ttaagtgtgc tgaagattta atagctatgg
    33301 agtgtgaata tttgcaaggg tattattttt ctaaaccagt tccagaagat gtttttaaaa
    33361 atttgttgaa agaaaatact tttacaagtt aacacccttt atttttttaa ttacaacttt
    33421 gttcattgac actgccagcg atatattata aaattaacac aataataaat attaaattta
    33481 ttatacatat tattaatatt aattaatgga gtaaagattt attatatttt atttaattat
    33541 cctaaagtga gaaaggaaga tgtgacatga ataaaaagaa aatattagtg ccaattgatg
    33601 ggacagaaag aagtatgcat tctttggaat ttataaaagg aatatttaaa aaagatgaag
    33661 ttgaagtaga aataatgaat gtaaaagaac tagtatttat tgatggcata tccctggctg
    33721 aagagataaa aaattctgaa aatttaggaa gaagaatctt ggataaagca gcagagataa
    33781 tgggagagta tgatgttaaa gtacatttta cttttggata tccaggagat gagataatta
    33841 gaaaagcaaa agaagataat gtagatttta tagttatgac aaaatctact aaaaaaggtc
    33901 ttacaagaat gataggttca gtaacagcaa gtgtagttaa acaagcaaaa tgtatagtga
    33961 tgattgtacc ggagtagaat tagaaaggta tttgaaatat gaataaaaag atagtagcag
    34021 tttgtgaaag tgaaagaagt ttaaattctc ttaagacagc tgcaaatgat ttaggatttg
    34081 atttagttta tgaaattcaa gaaaatgata atataaaaaa tgaactttct atttatgata
    34141 tagaagatgc atctatagtg ttatttgtta caagtgattc tatagaaagc atagagaaga
    34201 ttgatagatt tatagataga gaattttatg aagttgatcc aaagtatata atagaggatg
    34261 caaaatctat agtaagtgaa attttaatag acttaaatta atcgtgggtg tcgcactaag
    34321 aatagagcga cgccttttta catattttac ataagaaata aagggctgtc tcaaactata
    34381 gataagactc tttttcattg ttgaaatgat gaaaatatat ttgatttcat acaaaaaaga
    34441 gtgcctcata actaaaaagt tcactttgag acactccatt tttatatgtt agttgcattt
    34501 aaggtaaaat agaagtttaa tcatgttgaa ataactgaat tacatcttct aaatgattgt
    34561 acattgatgt ataacctaag taagagtctt tactatcaaa tgccatcatt atcttgttat
    34621 ggtggctaat catatcctta agagaatttc tatatttaaa accgaagtat tggttagaag
    34681 aaactgtttt aggtattaac tcataatatt ttataaaaat tggattatga gaagctaaaa
    34741 ttatctcttt gtgaaattgt aagtcagcat cataacattc ttctatcaaa ccatgagaaa
    34801 ccttatccaa ttcctctatt gactttaggt aagtatattt tattttttga agttctttag
    34861 atgtagcatt taaaattgct agtttagtag cttcactttc gataagttgt cttgctctta
    34921 aagattctac ataaaattct tgtatgttat gatttttata gatttcacca tcatcaaata
    34981 ggtcaacttt tttaaatcct tcaactatag gacttgagta aggcacagct ctaagtattc
    35041 cttccttaca gagtatattt atggcatttc ttacaggtat tctacttatg ttaaataggt
    35101 cagcaatctt tctctcactt ggtaatttac tattaatttt aaaagttcca tttagaatgt
    35161 ttaatttaat ataatcaata attttttcag tggcatttaa gcttttcata aaaactccta
    35221 aacatataat ttttttatga ttgtattata tcatagttaa gagttaaatc tactttttta
    35281 taatatgtat aagacaggat agaggccaaa atagctataa tagccaagat aaagtatcca
    35341 tattgtattg aagtatattc cgatatttta ccaactatca ttggaaatac agacattcct
    35401 atagcataaa ttgcttgaaa aaaacccatt gcagtagatt tctgatgttt tggtacattt
    35461 ttcatagact cgctagtaag gtaagaaagg agtatacctg tagatatacc tggtagcact
    35521 tgtagtacaa atattatatt aatatttttt attgttggaa ctaaaaagca ataggctgaa
    35581 actaaaataa aaactaaagg aatccaaaat tttggcccat acttagtaca aaatttagta
    35641 gaagcaaagc cagaagaagc aacagcacac accatgtaag atatagaaga tagacctatg
    35701 agggtagaac tagaacctaa gtttttaaga atttgagtag taaatgacat tgttgtagac
    35761 atttgaatac cctgttgaat taatgccata aaggaaaaaa atacaagtct tttatctttg
    35821 cagatagata aatatttttt aattgatatt ttttcaggta ttttttttga attatgattt
    35881 tttatattta aggctagaat cgttccaata actgaagaca atacactcat gatacataag
    35941 gctgtcattc ctaatttttc ataaaataaa gtactcataa caaatccaat caacattcct
    36001 agattgttta ccaatattat cgtactcgta gctttttgtt gatgttctgt agaaaaaaag
    36061 ttggtatagt gaaccatgta agaaatccaa gttgatgatg atattccaga taaaatgtta
    36121 gctataagaa aaccattgcc tccaggagaa aagactctta taagagatgc taaaccagca
    36181 aagaaaattc cagacagtat aaatatttta tgtttattta tagaatcagc aaatactcca
    36241 acaggaatcc ttaataaaca ttgtgagatt ccatatgcac ctattattat accaatcata
    36301 tttgtagata cattacatgc acttaaatat ggattttgga aaggtatata tacatattgt
    36361 gaaaaccaga aaaatgtaac aatagaaagt aaaagtaatt tttgattaga tatttttttc
    36421 atattatcct ccatatggta tttttataat gcaaataata taccatttag attttttaat
    36481 caagtacttt ctctattaaa aaaaatttaa atatataatt attatttaca aaaaaattat
    36541 actttatagt tgaattaaga aaacgcttat gatactataa agttaacaaa tttgaatata
    36601 taacagtaga cgtgttactg gtaatgcagg caagatcgaa tcaattttta tagattatct
    36661 atagagtact atgggtataa tctatttatt tggttcgatt tttttgttta attggccata
    36721 aaacaaaaag cctatagttg aaaatggagg attttttatg gattataaaa atatagctca
    36781 agaaattcta ctaaatgtag gaggaaaaga gaatgtaaat gaagtgactc attgtatgac
    36841 aagacttaga tttaaagtca aaagcgcttc taaagtgaat aaggataaat tatctaaaac
    36901 tgaaggagta ataactgttg ttgagagtat gggtcaaata caagttgtaa ttggaaataa
    36961 agtaaaaaca gtatatgatg aggttataaa aattgtacct caatcaaatg acgtaggtaa
    37021 aaagaatgaa agtcaagaaa agcaaagtat aattaattct atattatcag cagtagctgg
    37081 tatatttaca cctacaatac ctgctatagc aggggttggt atgattaaag gtattttatc
    37141 agttcttgct atgtattata tgaataaaaa tggagtagat ataaaagaaa cgcaaagtta
    37201 tattatctta aatgccatgg ccgattctat attctatttt atgcctatta tactaggata
    37261 tactgcggct aaagtattta atgcaaataa aataatatct atggtattag gagctacact
    37321 ttgttatcca acttttactg ctttgatggc aggtgaagaa tctgttagat ttttaggatt
    37381 ggcagtaaca aaagctacgt atacatcatc tgttattcca ataattattg ctatatgggc
    37441 tctttcatac gttgaaaaag tattagaaaa gtatatacct gaggtaatta aaataataat
    37501 ggttccaact ttatcattgg ttgtaatgtt acctgcaaca ttatttttat ttggaccaat
    37561 cggaatttat ataggaaatg tcataaactt ttcttataag tatatttatg aattaagccc
    37621 agcgttgtgt ggagcatttg taggtgggtt atggtgtgtg ttggttatat ttggtgctca
    37681 tagagcatta ttaccaatag gtataagtga tgttgctcaa acaggaagac agaatttatt
    37741 ggcatttgca ggagctgcaa acttttcaca agcaggggct gctctaggag tattctttaa
    37801 aactaaaaat caaggactaa aaacaatttc tatgtctgca actataacag ctttatttgg
    37861 tataactgaa cctgcaatat acggtgccaa tcttagatta aaaaaaccta tggtatgtgc
    37921 cgtaatatgt ggtgcatttg gaggtgcgat aatgggaatg ggtggagctt atggtaatgc
    37981 atttgcaaac caaggtgttt taactatacc tgtatatgct gaagcaggtg cattaggttt
    38041 cttaagttat ctaggtggtt gtgctatagc attttttggt tcagctattt caacttatct
    38101 agttggattt gaagatttgg aagagtcttc taataaggaa aattcattta taaaagtaga
    38161 aacgaaggat ggtgttattg atataacttc acctgtagag ggcgaatgta tagaattgtc
    38221 agaagtaaag gatgatgtat ttgcttcaaa agctatggga gaaggtatag ctgtgttacc
    38281 tacaaaagga gtaataacag cccctactga ttgtgaagta gcttctttat ttccaacatt
    38341 acatgcaata ggattaaaat tagataatgg agcagaaatg ttaatacatg ttggaatcaa
    38401 tacagtagag ttaaatggta aatactttac aaaacatgtt aatcaaggag atttagtgaa
    38461 aaaaggtgat aaacttatat cgtttgatat agataaaata aaaaaggctg gttatgatgt
    38521 aactacgcca gttatagtaa acaatacatt tgattttggg caagtagttt cttgtaaatc
    38581 tagttatgtt tcaaccaatg ataatataat ttcattagta ttagctggta attaagttaa
    38641 tttgactaga gataagtaaa ttgatttaaa aggaaataag taaatcaaca attaaataca
    38701 tctaaaagta agtttattgc aatgaattgt taaagaaaat aattaatatg gagtaaagct
    38761 attgcaatga agtaacaaag aaaataatta atatagagta agtttattgt aatgaattgt
    38821 taaagaaaat aattaatata gggtaaatct atctcaatga aataacaaag aaaagagtta
    38881 atatagagtg aacttattgc aatgaatcaa caaaaaaaat aatcaatata aaaaggagaa
    38941 atatttatga atacaggatt tccaaaagac tttttatggg gagcatcatc ttctgcattt
    39001 caagtggaag gagcttggga taaagacaat aaaggaaaaa ccgtagccga ctataattct
    39061 tttaaaaagt ctcatttaca ggcagatact aaagttgcat cagactttta ccataattat
    39121 gaagaagata ttgaattaat gaaagaatta gggatgaaaa catatcgttt ttcaatttca
    39181 tgggcaagga taataccaga tggtgaagga gagataaacc agaaaggttt agacttttat
    39241 aataagataa tagacaaact aatagagtgt gatattgagc cattcgtaac tttataccat
    39301 tttgaccttc catttaaatt agtagagaaa tataatggtt gggaaagtag agaaactgtc
    39361 tatgcttttg aaagatttgc taaaatatgc tttaagcatt ttggagatag ggtaaagtat
    39421 tggcaacctc ataatgaaca gaatttaatt gttagagtgg aggagagaat taatatatat
    39481 gatgaaacag attcatggaa gatagataaa atgcgtgctc agatggatta taatctttgc
    39541 ttagcacatg cattagcagt caatgcatgt catgagatga taaaagaaag taaaattgga
    39601 gcagcagtat catcatctgt aacatatcct cttacttcta agccagaaga tgtatatgca
    39661 gctagaatga atgataattt taaagtgtac tatatgcttg atatgcatca ttatggagaa
    39721 tatccagggt attatatgaa gtatcttgaa aaaagaaata cagttcctca catggaagat
    39781 ggggataaag agatacttaa aaaagctaaa atggatttta tagctgtaaa ttattatagg
    39841 acaaattgtg cagaagcttt acctgaagat tcacaacatc catttggatt aagagaagga
    39901 actgttgatt ttagtatgta tggactattt aaaatgtcaa tgaatcctaa cttagaggct
    39961 tctgagtatg gagcagcaat agacccatca ggtcttagag ttgccttaaa tgaatattgg
    40021 caaagatatc acttacctgt tataataaca gaaaatggtc taggagctaa agatatatta
    40081 gaagatggaa aaattcatga tgactatcgt atagactatt taagaagtca tataaatgca
    40141 tgtaaactag ctattgaaga tggtgtagag atgattggat attgtccatg gtcatttaca
    40201 gaccttttaa gttcttctca aggttttaat aagcgttatg gacttgttta tataaataga
    40261 actgaccatg aagttttaga tttaaaaaga atcaagaaag atagttttta ctggtataaa
    40321 gaagttatag agaacaatgg aatagtaaaa taaacataaa tatatattga gggttttagt
    40381 atgtacatta caaaggtatt aaataattcg ttgctacttg caaaggatga taatgatgaa
    40441 gaaataatat tgatggggaa aggcattggc cataattata aggccgggtc tgagttaaat
    40501 aaaaaagata tagaaaagat ttttgttctt catgatgaaa atataaaaaa gagtattata
    40561 caattggcaa cagaaataga tgcagaatat tttggtatag ctcaaatgat aattgcatat
    40621 ggaatagaaa aatataactt aaaacttatg aaccatatat atttggcctt aactgaccac
    40681 attgcctttg cagtgagacg ctttaaagaa ggtataatga ttgaaaatca ctatttgttc
    40741 gaaatcaagg aatttaatcc aaaagagtat gatataggaa aatatgctat tactgttttt
    40801 aaggaggttc ttggtttaga cctaccagaa gaagagattg gtaatatagc aggccatttt
    40861 ataaatgcac aacaagataa tccttatagt gatagaaata agagaagtgc taaaattgta
    40921 aatgctattt tgcaaatagt tcattatcac ttttctattg tatataataa agagtcattt
    40981 tattatagga gatttgtaat gcatctaaag gccttttcac aaagatttct ggctaatgaa
    41041 ccatcaagag aaaaaataga ttttatatat gagcaagttc aaaaaaattg taaggaagag
    41101 tatgaatgtg tgaaaaaggt aggagcttat atgtataagg aatactccag agaattacca
    41161 agacaagagg agttatattt gatgattcat attcataaga ttttaggaga attatgcgaa
    41221 aatagttaga atatcttaat atgctagtaa tattataaaa aattaaaaat taactacact
    41281 ttaaatatga acaattgcat tacttaaggg ggttgtctta aaattgattt ttttaattaa
    41341 atttgaagct caactccttt tttaaacctt tatatcatta caactttaat gtttatacgc
    41401 ctgtacttta gatgtatatc tactttttac atttctcaac atgcaaacct accatttttt
    41461 gcagtatgtt aattgaaata aaccattgag ttaaccctaa atttattctg gacttatagg
    41521 aatagttcca aagatacttt aaaatatttt ctggaataat tgcttatttc acatatgttt
    41581 tattgtgatg ttttgattta ataaattctt caactctgta tatagtaaat gtattatcat
    41641 gtttgtttta ttcaagcaca cttataatac gcttgatttt ttcacaatga tgaaatatac
    41701 taatgggtgt tataggtata agaatcgaat tacacttgaa gaagtaagtg ataaatgaga
    41761 tataaatcct catatgataa actactattt cattgaggaa catattctaa gtgatgtcaa
    41821 gatactacaa tatgactaaa ttcctagtga taaaaaagtc tacgaatgag tgtagaaagg
    41881 ggaactaaga tgaataaagt tttaattata gatgatgata aagatctttg tattttgtta
    41941 aaaaagagta tttcaattga acagattgaa gcaaactatt gccattctgg gagagatgga
    42001 ctggttgaac tttcaaaaca agattatcag ttagtagttc tagacgtgat gatgccaggt
    42061 atggatggtt ttgaaactat ggaacaaata cgaaaatata gcagtattcc catcttaatg
    42121 ctgacatcaa aaagcgataa ttacagcaaa gtgcatggat tgcgagctgg tgcagatgac
    42181 tatctaacca aaccatttga aattacagaa tttactgctc gtgtactgtc tttaatccga
    42241 cgttacaccc gttttaatcc aaaaaatgag gaaccacagc aactttcttt caaaggtttg
    42301 ttgattgacc ttgaccagca tacagtgact accaatggcg aacctatgtt gcttccaccc
    42361 aaggaatttg gtgtgcttct ttactgtgca aggcatcagg gtaagatttt gacaaaacag
    42421 cagatttatg aagctgtgtg gggtgagcca tatgtatatg atgacagcaa tatcatggct
    42481 attatcagtc gcctaagaaa aaaaattgaa ctagacccat catctcccat ctatttgcaa
    42541 acaataaaag gaattgggta tcaattcaac acggaggtat gaaaatggat gaacaaacga
    42601 taattctttt cttattcttg ctgtcgattg gtctactttt tctttccata tttgcttttt
    42661 ccaagcttgg gcatattcac aaacgcctaa aagatataga ggagatactg gctgatgtac
    42721 aaattggaaa cgaaaatcgc aaaatactaa ttaagccatg tgatgttatg gctccattgg
    42781 tttatcagct taatgagatt gtctacgatt atgaaaataa gttactttct ctgaaaaagt
    42841 cggataaagc tagcaaacaa cttatgacaa gtctatctca tgatgttcgt acaccattaa
    42901 caactctgat tggttatctg gatgctgtac acagtggtat agttatcgga caagaacggg
    42961 aggaatacct tgaaatcgct aggcgtagag cctacgacct caaggattac attgatgttc
    43021 tttttgactg gtttcggttg aactctgatg aatttacgct gtcaatagaa tctgtggaaa
    43081 ttgcagagtt gtcacgcaat attttgaaag actggattcc tatattccat gaaaagaaac
    43141 tgaattttga aattgatatt ccagaaaatc gactaatggt aaatctcgac ccagatggat
    43201 attcccgtgt ggttaataat ctggttcaaa atgttcttgc tcacagtaag gctcggcaaa
    43261 tcaagattac catgagtgag gattccagaa tggtattact ccgtgttgat gatgatggtg
    43321 ttgggattgc cagagaaaat ttaccacata tttttgagcg actgtataag tgtgataaag
    43381 gacgttcaga aaaaggaagt ggtcttggtc tatctattgt cagtcaaatg gtggagcgaa
    43441 tgggtggtca gatttccgta gaaagtgaga ttggaaagta taccgtattt acagtgagct
    43501 taccattaat ataaaattgt ttttccccca tgtgacatgt atacacaggg ggattttttg
    43561 taagttataa agttgcaagg ttaatacaag gttgttgcaa ggttaatgta agattgaggt
    43621 ggtatgatag ctttaataaa caaaggagga ttttattatt tatgaataat ttaattattg
    43681 aaacaaaaaa tctcactaag caatatggtg ctcaaaagag cgtttctaat ttgaatattc
    43741 acgttcagaa aggtcgcatt tacggattgc taggaagaaa cggtgcgggt aagacgacaa
    43801 ctatgaaaat gttattgggt ctaacaaaac caactactgg agaaattaaa atatttggtc
    43861 aggacattca caataacgag aagaagcttc ttcctcgaat tggatgtttg attgaatcac
    43921 cagggtttta tcctaatctg acaggaacag aaaatctcaa aatctttgca aggcttagag
    43981 gaataccaaa aaaaaatgca gtagaatcag cactggatgt agtcggtttg ccaaacaatg
    44041 acaaaaagtt attttctcaa tactctcttg gtatgaaaca gaggttggcg attgctcttg
    44101 ccattatgca tgacccacaa ctgttgattt tggacgagcc tatcaatgga cttgatccta
    44161 ttggtattgc agaagtaaga aagtttattc gtgatctctg cacagaacga ggtaaaacta
    44221 ttttgatttc cagtcacatt ctttctgaaa ttgccttgtt ggcagatgac attggtatta
    44281 ttgaccatgg tattttgttg gaggaagaaa gtcttgccca attagaagaa aaaaacagta
    44341 aatacataca ttttgctgta tctgatgcag cacatgcagc aaggcttctg gaaacccaac
    44401 ttaacctgaa aaatttcaaa gtagcagata attacaatat tatgctatat gatacagatg
    44461 tttctgttgc agaaataaat cgtgctttca ttctaaacaa cattgaggta tcagaatctc
    44521 atttatgcga agatactctt gaagattact tcaagaaagt aacagggggt gaaggaattg
    44581 cttgatataa tttcatgtga attttcaaaa ctcaagcggt taaaatttat actgatttct
    44641 attttaggtg cttgcttatt tccaattccc gcaacaattt tgattgcaaa ggacaacttg
    44701 ccctttgagc aattgttcaa attagttgtc aattttggat attttttgct attaccaatt
    44761 gtattaagta ttgttgctag ccaactattt tttatagaaa gagataacga tgtattaaaa
    44821 aatcttgcaa cagtgccagt gccaaaagga aaactggctc tggcaaaatt ggctgtgttg
    44881 ctgtttatat cattgttcta ctccgttgca gggttaggag ctactatcat tggaggtttc
    44941 attgttggaa tagtagaggg ggttactgta aaattaggaa tgagcattgc ttttggaatt
    45001 atgttttttg ttactgtact tcctgttgtg gtactcattg tatatttcaa tcgcagctat
    45061 attttttcta ttatactttc ttttgtatat gctattttca attttagtat atccttaaat
    45121 attatcaatt ttgaaccaaa taacccacta ttaagcgtat tacctgctcc tgttataatg
    45181 cgttggtgga tggcattttg gggagatccc actggcgaat acacggcact tagacagcca
    45241 tatttgctct caactcctgc ttgtgtaggt attttatgtt tgataaccat tatagcagtc
    45301 ctgctgattt gtatgatata caaaaagcag gagaattagg aggtatctat gcttgatata
    45361 attactacag aatttcaaaa aataaaaaga tataatattc tatggattgg tgttgttgct
    45421 gttctgtttt cagcactatt ggcagttttt caggttgtaa gttcacacgg cagtgaccct
    45481 ctaacgtatg agagctttgc aaacggagtt atctggaata atttcagtct tagttttcca
    45541 tttgggatta cacttattgg aggatatctt attaaccgtg aatatacaga ccaaacctta
    45601 aaaaacatcc taactgttcc tatttcatta cgcaaattgc tagtgggaaa attaattgcg
    45661 gttggaggaa ttgctgtatt gttaagtctt ttcagcttct tatgcacatt tattttgggg
    45721 ttgttatttt gcaatatcaa tatatctgtt acactcattg taaaatcctt agttcagatt
    45781 ttgtctgtta atctgtattg ttatgttgct gttttgccga ttattgctta ttttggtcgt
    45841 aaacaaaatg catttctgac gggtgtaggg attgcatttg tatacgggtt ttgtggtgtg
    45901 tttgttgctg gaagaaatct gacagacttt tatccaatca cagcaggtct tggtctagtt
    45961 ggatacaaca atggtgctgg tactgtttat cagccactta tcggtgctat gactttgatt
    46021 gtaattctaa tcttgacaac tattctactt gtatttacac ctaattatga taaagttatg
    46081 accatatcta agaaaaaagg gataaagcat aaaaagtatt ctcataaata acataaatat
    46141 tgtttctatt atttaagttg ctagacagtg aaaagaaaaa atctgtcgta cagtggctat
    46201 atgctcatgt attcaagaag ctacagtttt gatttttcat aactgtagct tctttttgta
    46261 tttattaaat cacggctatc ataatacttg caataggtat agcgacaaga gagagtactg
    46321 tcatgtgtgt tttatatatt acattaagta tattctaaaa tatatgtttt aaataatata
    46381 tttgaaaata ggaatattta aataaaaaaa ataatattat atatagttga caaaaattgg
    46441 caaatgatat aatatataaa tatagaaata gtaatcatta ctattattaa aaagggagga
    46501 attaattatg aacttaaaag gaactaaaac agaaaagaat ttaatggcag gatttgcagg
    46561 agagtcagaa gcaagaaata aatatacata ctacgcttca aaagcaagaa aagaaggtta
    46621 taatcaaata gctgctatat ttgaagaaac tgctaacaat gaaaaggaac atgctaaatt
    46681 atggtttaaa cttttacatg atggtatgcc ttcaacagag gaaaatttaa aggatgcagc
    46741 agcaggtgaa aactatgaat ggactgatat gtatgcaaaa tttgctaaag aagctagaga
    46801 agaaggattt gacaagatag cttatttatt tgaagctgtt ggaaaaatag agaaagagca
    46861 tgaagaaaga tacttaaagc ttttagaaaa cttaaatgaa ggaaaaatat ttaaaagaga
    46921 tgaagaagtt gtttggcaat gtcaaaactg tggtcatgtg tatgtaggta ctgaagcacc
    46981 agaaaaatgc ccagtatgtg accatccaaa agcgtatttc aatataaaag ctgaaaatta
    47041 ttaaaaatta tcattattaa aaaggaatgt taactatgaa attttctaaa caacgagaac
    47101 tgattttaaa tgaaatatta aataatccgg ttcatcctac tgcggattac ctatatgaaa
    47161 acttaaaaaa agataatcca aatttaagct taggaactgt ttatagaaat ttagctcagc
    47221 taacggaaca tggctttata agaaaggtta gtattccagg gtatccagat agatttgatg
    47281 gtcgaataga taatcactat catatcatat gtgaagtatg tggagaggta tacgatttag
    47341 aatccgaagt tcttaataat ttacaagaat taatatctga ggagacagac ataaaaataa
    47401 catcttataa cataagtttt aaagggattt gtaataattg taaaaggtgt agccaagtag
    47461 gttagttttc aaattctaaa aataattaat gaggtgagtt tatgtgtagt gaacaaaaat
    47521 tttttatatg tgagacttgt ggaaaccttg taggaatgat acaaagtggt ggtgtaccta
    47581 ttttctgttg tggaaaacct atgaaggaac ttgttcctaa tacaacagat gcagcagttg
    47641 aaaaacatgt acctgtaatt gaagtggatg gaaataatgt tactgttaaa gtaagtagca
    47701 caactcatcc aatgactaaa gaacatcata tagcatgggt gtatcttatg actgaacaag
    47761 gtagtcaacg caaatgtcta gcagtagatg gagaacctgt agttaaattt gctttgaatg
    47821 atgatgataa agtgatttct gcctatgctt actgtaattt acatggatta tggaaggctg
    47881 aactgtaata tttaaataaa ttgagtcaaa gaggaggcta taaatgtatt ttcatacaaa
    47941 tagcctccta taaatttata taaattcaag ttttaatttt gtttaatgtc aatataatat
    48001 aaggagaaaa taatatgtca atttataaat gtagtgtttg tggatatatt tatgatgaat
    48061 ctaagaatga taaaacatgg gatgaattaa gtgaagattg ggaatgccct gtatgtacaa
    48121 aaggtcgtag ttattttgga aagataagca ctgtttacta tgaagaagat gaaaagatag
    48181 cagaagacat agttgaaaat gaatctaaat taaatactga aaaagaggga gatttaaatt
    48241 acttaagtac atatttaaga agagatgatg aagttgagaa acatatggat ataattcacg
    48301 aaatggctgt tacaggaaaa tctataatag aacctatgag aactaaacta ccagtaattt
    48361 cttgggatga tattttaatt atgggtgctc aattaaatcc attaccttta aatgagcatg
    48421 atgaagtaaa tacaacaaca ataataggaa aaaaagcaaa gaaacctatg attatagaaa
    48481 atccagttta tatttcccac atgtcatttg gagctttgtc taaagaacta aaaatagctt
    48541 tagcaaaggg tgcagcccaa aataagacag ctatgtgtag tggtgaagga ggtatattac
    48601 cagaagagaa ggaagcttca tacaagtata tttttgagta tgtaccaaat aaatatagtg
    48661 taactgaaga aaatcttaaa aattctgatg ctatagagat aaaaattggt caaggaacaa
    48721 aacctggtat gggaggtcat cttcctggcg aaaaagtaac tgaagaaata gcaaaagtaa
    48781 gaaataagcc tgtaggtcaa gatgtaataa gtccatcttg ttttgaggaa atacaatcca
    48841 aagaggattt aaagaaactt atagatgaac ttagagaagt ttcagaaggg cgtccaatag
    48901 gtgttaaaat ttcagcaggt catattgaaa aagatatgga atttatagct tatgctaaac
    48961 ctgattttgt aactattgat ggtcgtggtg gagctactgg agcaagtcca aagttgctta
    49021 aagatgcaac ttcaattcca acaatatttg ctctttatcg tgctagaaaa tacatagata
    49081 cacatggatt agatatagat ttggttataa caggtgggct tcgtatatct actgattttg
    49141 ctaaggcaat tgctatgggg gctgatgcag ttgctattgc aagttctgct cttatggcag
    49201 cggcgtgtca acaatatcgt atatgtggtt ctggtaagtg tcctgtagga gtagctactc
    49261 aggatgagga attgagaaaa agattacata tagaaaatag tgctaataga gtggcaaact
    49321 ttttaaatgt aagtttagaa gaacttaaga cttttgctag aatttctggt cataaagata
    49381 tacatgattt aagtgttgat gatttatata ctgttaactc tgaaatatca aattatacaa
    49441 acatacagca tgtatagatt gaagtttgaa actattagat tttagatagc tataaaagta
    49501 aatgataaat atattttata aaagagagtg tcttaaaatg aactttttag ttcataagtc
    49561 actctttttt gtatgaagcc aaatatattt atcattttag caatgaaaaa gaatcttatc
    49621 tctttatttt gagatagact ccttctattt atgaaaatta aagatattaa attgtaaaat
    49681 attctgtgat gtcgtactat taaactaaag attctgtact ttaaagtaaa taaaaattta
    49741 aggagtgctt attatggaaa gattgaagat acaagtttta gttgacaata atacttatat
    49801 tgatagatac tttgttggag aaccagcagt aagctattat attgagattg atggaaatag
    49861 gattttgttt gattcgggat attcagatgt attcatatca aacgctgaaa aattaaatat
    49921 agatttagga aatttaactc atgttgtttt ttctcatgga cataatgacc atacaagagg
    49981 tatccagttt ttagaaaata ggtatgattt atctacagtt gaacttattt cacatcctaa
    50041 ctgttttata cctagaaaac atggagagaa aagcatagga gctccatttt ctgctgagga
    50101 aattaaaaat atttttatgt ataatcctaa ggataagcca tttaatctaa gtaagaattg
    50161 tgtgttttta ggtgaaatac cttctataaa taattttgaa aaaagagcta aaattggtaa
    50221 atgtaaaata ggagatttgt gggaagatga ttatgtttta gatgattctg ctatagtttg
    50281 taaaactgat aaaggtattt ttattgttac aggatgttct catagtggaa tttgtaatat
    50341 agtagagtat gctaaaaggg tatgtggaga tgatagagtt attggtatac taggtggttt
    50401 tcatcttttt gaattgaata ataggttaga tagtacaata caatatttgg ataaagaaga
    50461 aataagaatg ttgtaccctt gtcactgtgt ttcttttaag gtaaaagcta agatgaatga
    50521 aatattgaat ataaatgaag ttggagtagg gctgaccata agtatatagt atttgaaagt
    50581 atataagatt taagttgaag gttaaaaaga tattttctat ataaagtatc ttttttgtta
    50641 cgtttatttt aagagaaatc aatatacttt tatatgaaat attgtaaaaa aatttatttt
    50701 taatgagaat atattttcat taataaacaa ttttattatg tattaataat gctagaataa
    50761 atataaataa atcaaagtta cttacattaa agtatatttt ttcacaaaat atattgattt
    50821 attcttttaa agtttgataa ttccaatgaa tgtaataaaa gaagggattt tatactatac
    50881 aattattatt ataaaattat aaagaaaaaa ttaaataata ataaagaaaa aatgtataat
    50941 atttaacatt aaaaaagata tttcataaaa ttaaaaaaca aagtgaattt gaatactatt
    51001 taaaaaataa aaaaatatat aaaaaatatt taatacaaag gtagaaataa gttgaaaatg
    51061 taaagtcatt ggaaaaatat agttgaattt aatgaacaaa aatgttattg ttttatcaat
    51121 gaagtgttaa aataaaaact ttcaatatca ttttagggag gatgatttca tgcaaaaaag
    51181 tgtaaagaaa gcaaaagtaa cgggatctat gttagccatt tttggtgttg caagcgttct
    51241 ttttagttca catgcaggag gaggatttgc tacagggaat caagaaactc agtactatgt
    51301 gcagtatgga tggacagcac cacttatggc aattttagca atgattatac ttactgctac
    51361 catgagagaa gttatcataa tgtataataa taacaattgt aggaattata aggatttatt
    51421 ttgtgagctt tggagaccat atccaaaact tgaaataata tgggagatat attactatct
    51481 aatggtttta atagctgtaa gtgctgttat agcaggtgca gcagcagtat ttcaaagtat
    51541 aggagtaaat tattttgtag ctgtatttat tattggagtt gtacttcttg tctttactat
    51601 atttggtgct atgcttgtat ctaaagcagc tacagcaatg acaatagcta ttctagtatg
    51661 tactcttact atttttattg ttggtataaa agctaaagta ccagaaataa ctgaaatatt
    51721 atcaaataga acgagtttca cacctggcta tatcaagcca atacttaata cttttattta
    51781 tgcaggtttt caatcggttg ttatacctac acttgcagga tgttcaagac cacttcttaa
    51841 gaactcaaaa gaagctacta aggcaatgat aatttcattt gttatgaatg caattgcatt
    51901 aggacttgct gtaactatgc taatgggatg gtatagagaa attattgctg ctgggcaaac
    51961 aacactccct actctttatg ttgcaggtca atctggaaat catactatat acataattta
    52021 taatgttgca ttattccttt gtttaatgtc tacaggagta actactatat ttggtcttgt
    52081 aaatagattt gaagaccata aagcactttc tttcctttct tcaagaatga aaagaagggt
    52141 atttacagct tgtgcaataa tggtagtgtc aatgcttata tcacttacag gattaagtaa
    52201 tattgttaaa tatggatatg gatattgtgg ttatcttggt ctattcacta tagtaattcc
    52261 attccttaca ctaggacatt ataagaataa gaagtttgca aaggaaaatc cagaagctaa
    52321 atggccagcg gaattaaatg aaaatgtaaa ttagatgtag tagcaaaaaa tattgctaaa
    52381 gagaatacta taaataagaa tactatagat aatatatctg catgtttatt aagattattt
    52441 gcaaaatcta atattgaaca actataaaca agcaatataa aactaagaat aaaagataaa
    52501 aagagggtgt ctcaaaatgg acttttagtt tataaggcac tcttttttat atgaagtcaa
    52561 atatattttc attattttga caataaaaga gactaatcct actttggata gcctcttttt
    52621 tctttaatat aaaatagtat aacagcaaag tatagattga tacatgtttt ctgtagcttt
    52681 ctatatatta cagtgtttgt gtggcattgg tattttaagc aatctataaa ttataattct
    52741 ataattcttc tactaatttt agattctata gccgtctcta tttcacttaa cattcgttca
    52801 tttttagggt caataaaagc acatgtatag ccttcttcac cagctctacc agttctacca
    52861 atacggtgga tgtagtcttc tggtgtttct ggtaaatcgt aattatatat atgacttact
    52921 ccagatatat caaggccacg agaagctaca tctgtagcta ttaagtattg tatatctaaa
    52981 tttctaaatg atttcattat tctttctcgt tttgattgag caatatcact atgaagtttt
    53041 tgacaattat atcctcttat agcaagagct tcttcaagat tgtcaaccct tctcttagtc
    53101 ctacaaaata ttattgccat aaaaggatta tcttcatcta gtaccttaca taaggcatct
    53161 aatttttttc tatctgtagt ttctactact tcttgtttta tattattaag agtgatttct
    53221 tctttttgaa tagaaactac aacaggattt tttgtgtatc tataagctaa tttttttact
    53281 tgagaattta tagttgcaga aaagcatagt gtttgctttt tgtttgaagt ctcttttaaa
    53341 atagcttcca cttcgttttt aaatcccata agcaacattt ggtctgcttc atctaaaaca
    53401 aaagtcttta acttactaag gtctattgtt tttctattta gatggtctaa aagcctacct
    53461 ggtgtagcta taatcatatg aatatttcct tttagtttct ttatttgaga accaatatct
    53521 tttcctccat atgctgcaag aatacttaca tctttagatt ctttaagttt catagcttct
    53581 tctgttattt gaatagctag ttctcttgta ggagaaagta taagtacttg tatatcattt
    53641 atatctaatg atatattttc aaatatcgga agtaaaaaag ctagtgtttt tcctgttcca
    53701 gtttgagctt ctgctattac atcttttcct tcttttatta gtttaatact ttctttttgt
    53761 ataggtgtag gtgttgttat tcctgatttt tttagaatat ttattgtatt ttcactaatc
    53821 cctaagcttt tgaaatccat tgttatctta cctttcatga aaaattttct tttttattaa
    53881 ccaattaata atatcatatt tgtaagtatt tttagtaaat tttttaatta ttatttatat
    53941 agcttaaaaa tatattaaga tactttaaaa tggaatgtaa cttaacttaa attttagtag
    54001 gaattttata ggtttatttt taaaggtttt ttgaaaataa atctatttaa aaattaaatt
    54061 aaaatgcaag aaaaacataa taactttcat ttttaagaag ttttcacaaa aaagaaaaaa
    54121 tatagtgcaa taaatgatac aaagtaatat aatagattac aagatatgaa aagctaaaaa
    54181 aataaattgc aaatgaaatt aaaatgaata aaaaataaaa aaataatcat aagttagagg
    54241 tatcaatgaa aaataagact taatgttttt aaaattaaaa gtatactaag gggggcatta
    54301 atatgtgcgt tatatcaaaa gatagagcaa aggaaataaa aatagtagat actactttaa
    54361 gagatggaga gcaaacagct ggggttgtat ttgcaaatag agaaaaaata atgattgctg
    54421 aaatgttaag tgacctaggt gttgaccaaa ttgaagttgg tatacctact atgggtggag
    54481 atgaaaaaaa tgtaataaag cacatatgta gtagaaattt aaaatcagat ataatggctt
    54541 ggaatagagc agtaataaaa gatgttgaag aatctatttc ttgtggtgtt gatgcagtag
    54601 ctatatcaat atcagtatct gacattcata tagaaaataa attgagaact tctagaggct
    54661 gggttttaga aaatatggct aaaacagttg aatttgcaaa gaaaaatgga ttatatgttt
    54721 cagtaaatgg agaagatgct tcaagagcag atatagactt cttaactgaa tttataaatg
    54781 ttggaaaaca agcaggggca gatagattta gatactgtga tacagtagga gttatgaatc
    54841 ctttttctat aaagaatgca atagaaactc tttatgaaag aactaatttt gatatagaaa
    54901 tgcatacaca taatgacttt gggatggcaa ctgcaaatgc acttgcagga atagcagcag
    54961 gagcaaatta tgttggtgtt acagtaaatg gattaggtga aagagcagga aatgcagcat
    55021 tagaagaagt tttaatggca cttaagtgtg tttataaatg tgatttaaat aatatagata
    55081 ctagaaaatt tagaggaata tgtgagtatg tagcacaggc atcaggaaga atacttccta
    55141 catggaaacc agtagttggg gataatatgt ttatacatga atctggtata catgcagatg
    55201 gagctttaaa agacccgcat aactatgaac catttgaccc aagtgaagta aatcttgaaa
    55261 gaaaaatagt aataggtaaa cattcaggaa gagctgcagt tataaataag ttgagtgaat
    55321 atgaaatgta tatttctcca gaaaacgcta ccaagctatt aaatgctata agagctacat
    55381 ctataagatt aaaaagaagt ttaatggata aagaaattct tcaattatat tgtgatatac
    55441 tagcacatga gaaaggcaca acagaagaag aagcagttag aggttcatat atttaagata
    55501 taattgttta ggaggaaaat atgggagata atatagttta taaaataatt aaaaaacata
    55561 tagtagatgg agaagctgtt gctggaagtt caattggtat aaaaatagac caaactttaa
    55621 cacaagattc tactggaaca atgacatatc ttcaactaga agctatggga atagataaag
    55681 taaagactaa aagaagtgtg gcatttgtag accataatat gttacaacaa ggatttgaaa
    55741 atgcagacga ccataagtat atacaaacag tggcagataa atatggagtt tatttctcta
    55801 agccaggaaa tggtatttgt catcaagtat ttttagaaag attttcaaca ccaggagata
    55861 cacttttagg ttctgatagc cacacaccta ctgctggagg tgtgggcatg atggctattg
    55921 gagctggtgg attagatgtt gctttagcca tggcaggagg agcatactat ataaaagcac
    55981 caaaagtctg taaggtgaat ctagttggaa aattaaataa tatggtatca tcaaaagata
    56041 taatattaga agtgttaaga aaacaaactg taaaaggtgg agtaggtaaa gtttatgaat
    56101 atggtggaga aggtgtcaaa agcctatctg ttccacaaag agctacaata acaaatatgg
    56161 gggctgaact tggagcaact acttcaatct tcccaagtga tgaaaaaaca ctagaatttt
    56221 ttaagagtca aggaagagaa gacgcatgga tagagttaaa accagatgca gatgcagttt
    56281 atgatgaaga gattactata aacttggatg aattaaaacc attagctgca aaacctcata
    56341 gcccagacaa tgtagatgaa gttgaaaata taggcaagat taaaatagac caagtggcaa
    56401 taggaagttg tacaaattct tcttatgaag acttaatgaa agtagcacaa atcctgaaag
    56461 gaaataaagt acataaggat gtgagtttgg taatagcacc aggttcaaga caagttatgg
    56521 agatgattgc tagaaatggg gctttggcag atataataag tgctggagct agaatactag
    56581 aaaattcttg tggtccatgt attggtatgg gtcaatctcc aggtactgac tctgtgtctt
    56641 taagaacttt caatagaaat ttctatggta gaagtgggac tttgtcagca caagtatatt
    56701 tagtaagtcc agaagtggca gcagtaagtg caatcaaggg agtgcttaca gacccaagag
    56761 aatttgatat taaatttaca aatttagatg taaatgaatt tttgatagat gatagcatga
    56821 taattaaacc tgctgatgta ggaagtaatg tagaagtagt tagaggacct aatataaaac
    56881 ctttccctct taatacagag ctaagtcagt ctataggtgg aaaagttata ttaaagacag
    56941 aagataatat aactactgac catataatgc catcaaatgc taagttactt ccttttagaa
    57001 gtaatatacc gtatcttgca aactattgtt tcaatactgt agatacagaa tttcctcaga
    57061 gagcaaaaga caataatggt ggatttatag ttggtggaga taattatggt caaggttcaa
    57121 gtagagaaca tgcagcttta gcaccattat atctaggtgt taaaggggta atagttaaga
    57181 gctttgcaag aatccacaag gctaacttga taaatagtgg tataattcca atggagtttt
    57241 gtgatgagaa agattatgaa aatatatctc ttttagataa tctggagata ccaaatattt
    57301 tagacaatct aggtagtgga attttagaag ttaagaatac aactaaagga acttctttta
    57361 aggtcaaagt agaattgtca gcaaaagaag ttgacgtatt aaaagctggt ggaaaattaa
    57421 actacactaa aaatcaagct aattaatatg aaaagaggga atattgaatg tataaagtga
    57481 cacttatacc aggagatgga ataggaccag aagttgcgaa agctatgaaa aaggtagtag
    57541 aagctactgg agcagaaata gaatgggaag aagttaatgc aggagaggca gttattgaag
    57601 agtatggtac tccacttcct gaatatatta tagatagtat aaaaaagaac aaaatagcta
    57661 taaaaggccc aattactact cctgtaggta aaggatttag gagtgtaaat gtaactttaa
    57721 gacaggcatt agatttgtat gtcaatttaa gacctattaa aagttttaag gggataaaat
    57781 caagatatga agatgttgat ttagtggttg taagagaaaa tacagaagat ttatatgctg
    57841 gaatagaaca taaaataggt gattatgcag ctgaaagtat aaagataata acaagaagtg
    57901 caagtgaaag aatcgttgat tttgcatgta actatgttaa agataataag agaaaaaaag
    57961 ttacagctat acataaggca aatataatga aaatgtctga tggattgttt ttagatgtgt
    58021 ttagagaagt tgcatcaaaa catggtgtag aatatgatga tttgattgta gatgcagcag
    58081 ctatgaactt agttttaaat ccagaaaatt atgatgtaat ggtaatgcca aatctttatg
    58141 gagatatact atcagattta ggtgctgggc ttgttggagg tttaggtata attccaagcg
    58201 caaatattgg taaagattgt gcgatatttg aagctgttca tggaagtgct ccacaaatag
    58261 caggtcaaaa taaggctaat ccaacagcac ttattcaatc atcagtaatg atgcttagat
    58321 acttaggtga atatgaaaat gcacaaaaaa tagaaacagc tttagaaaaa gtatttcttg
    58381 aaggaagtaa attgactgta gatttaggtg gctcagcttc tactacagag tttgcggatg
    58441 aggtgtgtaa gtatattgta tagattttat ttagggaaaa agtgaaatat agattgaagg
    58501 aaagaggctt tctcaaaata gagataagcc tttttttatt ggaatgataa aatatatttg
    58561 attttataca aaagagagtt cctcataaac gaaaaagtta attttgggat atccatttta
    58621 attttaaaat taattgatta atacgcaaag aaagattaaa caaatttatt atttttaatt
    58681 gaactttcaa ccaaaatatg gtaaaattta aaaaagttga actttcaact aaaaataaat
    58741 atattgatta tgtgaaattc tataaaacag aaactatttg actttagtca tggtaggttc
    58801 agtggaggtg tgtttgatta agactttaga tagtaatata ttaagagaag taggtacttt
    58861 atctagagca gtaaattcaa taaatgatat taagtacaag gaattaaagt tacaaaaagg
    58921 acaatttaca tttttgacaa gaatctgtga aaatcctggt ataaatcttg tggaattatc
    58981 aaatatgtta aaggtagaca aggctacaac aaccaaggct atacaaaaac taataaaggc
    59041 aggatatgta gataaaaagc aggatgagtt tgataaaaga ggatataatt taactccaac
    59101 tgataaatct ttggaagttt atgagttgat aattgaagaa gagaatagaa gtatagagat
    59161 atgttttgat aattttacag atgaagaaaa acaagtggta actaagttat tagaaaaaat
    59221 gagcaaaaac gtagaaaatg aatggtttaa agtaaagaga tagtaaataa atacattaac
    59281 ttaaggagat atttttatga ttagaaaagc gaatatgaat gatttagaaa gcattatgaa
    59341 aattataaaa tctacagtgg aagaaatgaa gacttataat aatacacaat gggatgaaaa
    59401 ctatccatta gaaaaagact ttgtttcaga tattaagaaa caagatttat atatttatga
    59461 agtggatgga gaagtagcag gatttatatg tcttaattat gaagagccag aagaatattt
    59521 aggcttaaat tggtcatcta ataaaaaagc aatggtaata catagaatgg ctgtaaatcc
    59581 aaactttaga aagacaggaa tagcatctaa gttagttgat tttgctgaaa aattagctgt
    59641 agaaaacaat gtatcatact taaagagcga tacatattca ataaactcaa aaatgaattt
    59701 attacttaca aagtgtggtt ttataaaaat cggagaaatg agttttttag gaaaggagaa
    59761 atctttctac tgttatgata aaatattata aagagcattt ataatacaag gggtaaataa
    59821 tagattttca gcattagtaa gggcataata taacccagta tatgctatta tgaaagggat
    59881 gatttatatg attggatttc taaagaaaag aagaagtatt agaaaataca aggatgttga
    59941 agtagaaaaa gaaaaattag ataaaatatt aaaagctgct cttttagctc catcatcaaa
    60001 ggggcttaga acatgggaat ttatagtggt agatgataaa gaaaagctaa ttaatttatc
    60061 tcaatgtaga actaagggtg gtggattttt cttaaaaaat gcacctttag ctattgtaat
    60121 tattgcagat aaagaaaaaa atgatgtttg gatagaggat gcaagtatag ctgcttcata
    60181 catacaactt caagctcatg aactaggttt aggttcttgt tggatacaag taagaaatag
    60241 aatgtatgat gataatatag aagctgataa gtacattaga gaagaattaa aagtacctag
    60301 caagtacagt gtagaatgta taatttctat aggatattct gatgaagaaa agaaagcata
    60361 caatgactct gatttagact ataaaaaggt tcattttaac aacttttagt atataatatg
    60421 ttgtattaag acattatatt tttttctatt gttaatatat acttaaaatt gtaaaaatat
    60481 atctgaattt tactaactta tctaggggtt atgtacaagg attttaaaga taaatataga
    60541 aattaatgtt tataatcgat acataacttg agtaacaaaa tttaaggagg ttaaagtatg
    60601 ggtatattta aaacaaaaat ggatgaggac tggaaagtaa actacattaa agagtttaat
    60661 gaaatgagag attcttatga gagtaaactt caaaaaaaac agtttgaggt agatagtttg
    60721 aaatcagaat tggatagact aagaagctat aaaaatagcc ttaagccaaa agaaaaacaa
    60781 attactgatg atgatataaa taatataaag agtttaagaa gagatggctt aagctataaa
    60841 gaaatttcaa atcaaacaag ttggagcaaa gcaactgtaa gtagggtatt aaatggactt
    60901 tacgattagc atatacatgg ggtgatttaa attgggatga agtatagtta caaaaaatgc
    60961 ataatagatt ctattttatt gatgtttata attcaaatat taaggatgat tttgaattat
    61021 gtacttctaa gtcaatttga atttactctt gaaaatttta atattataaa cttaatttct
    61081 tttacattag ttggtttatc gttaatttta tttttaaaag ataattcttt gtataacaag
    61141 gttagaaata gaaaaatcac agaagctttt gaagaaaata aaaacaatat acttattgaa
    61201 aagtgtaagc ttatactttt tgttgtggtt ttatctttag caataattgt aacttattgt
    61261 actaagggat atgtactttt taatgtaact atgatgactt tgtctgtatt gatagttcca
    61321 atatttgaag agttattttt tagagaatat atatggaact atctaagtaa ttttataaag
    61381 tcaaagagta aaattatctg tataacatct atactatctg gaatttataa tataggatac
    61441 atagatgtta taagaaatta tgtaatattg tataacaatt caagctacac ctttgaagtt
    61501 attatttcaa aaattatgat aggtactgtt tttggtattg tacttggatt agttaagtat
    61561 aggtttagag atgtagggtt ttgtatatta ttgaggagct tatttgctat atttattagg
    61621 tagatagtat aatcggttta taaggttgtt ttaaatttaa ttttaaatca accttatttt
    61681 atttgtgttt tataaaacac ttatatatta ataactaata aatttaataa agattatttg
    61741 aatattttta aaatatataa atatgtattg acatataaat attatgaatt acaatttata
    61801 taaactaata aaaattaaat aatattaatc aacttattga atggaggaat aaaaatgaaa
    61861 tttgtgactt tttgtagtag caatgaagaa aaaataggtg tatttaattc agaaacaaat
    61921 agtatatatg aaattaatag tttaggatta agtaaattat atactgatat gaatgatttt
    61981 attgaaaacg tatctacagg agatttagaa aaaataaaaa acaattcatt tgaaaacgca
    62041 aagtgttata agttagaaga agttaaatta tgttccccaa ttgtaagacc taaaaaagat
    62101 attatatgtt taggtctaaa ctataaagac catgtcaatg aaatcccaga tggagttata
    62161 aaaaacgtag ttatgccaga ttatccaatt tatttttcta agagagcaga caaaataatt
    62221 ggagtggatg ataagataag cttacatgga gatttggtag agaagttgga ctatgaatca
    62281 gaacttgcag taatcatagg taaagaaggt ataaatatat caaaagaaga tgcttatgaa
    62341 tatatatttg gatatacaat agtaaatgat ataagtgaaa gagcacttca agataaacat
    62401 gttcaatggt ttagaggaaa aagcttagac acacatacat ctatgggacc ttgtatagta
    62461 cataaagaag aatttgaaca tcctttaaaa ttagatataa gtagtgtagt aaatggagaa
    62521 gtaagacaaa attctaatac agagtacttt atatttgata tacctactat aataaatgat
    62581 ttatcaagag gaatgactct aaagccagga gatataattt caactggaac tccagcaggg
    62641 gttgctatgg ggatgaatcc tcaagtatat ttaaagcatg gcgatatagt tgaatgtaaa
    62701 gtcgaaggaa taggagtttt aaaaaatata gttgattaat ggataaatat gccatataat
    62761 tttattagta caaataattt aattaatata ggattgatca aacttatgat taatttatta
    62821 tagagaggga tgagtatatg gcaagagaac tagaattaaa gtatggctgt aatccaaatc
    62881 aaaaaccatc aaagatttat atgaagaatg gagaacttcc tatagaagta ttaaatggaa
    62941 aacctggata tataaatttt ttagatgcat ttaatagttg gcaacttgtg aaggaattaa
    63001 aagaagctac aggtcttcca gcagcaactt catttaaaca tgtaagtcca gcaggagcag
    63061 cagtaggggt acctttatca gatactttaa agcaaatata ttttgttgat gatttagagc
    63121 tttctccatt agcttgtgct tatgcaatgg caagaggagc agatagaatg tcttcttatg
    63181 gtgattttat agcactttca gatgtatgtg ataaggagac tgcaactatt atagcaagag
    63241 aggtttctga tggtataata gctccaggat atacagatga agcccttgaa atattaaaag
    63301 gaaaacgtaa aggcaactat aatattgtaa aaatagatga aaattatact cctgagccta
    63361 ttgaaacaaa ggatgtttat ggaattactt ttgaacaagg tagaaatgaa atattaataa
    63421 atgaagaact attaaaagat attccaactg cgaataaaat ttttacagat agtgcaaaac
    63481 gtgatttaat tatagctctt attacattaa aatatacaca atcaaattct gtttgttatg
    63541 ctaaagatgg acaagtaata ggggtaggtg caggtcaaca atcacgtatt cattgtacta
    63601 gacttgcagg taacaaagct gatacttggt atcttcgtca acatcctaaa gtattaaact
    63661 taaaatttaa aaaggatata ggtcgtccag atagagataa cactattgat gtatatcttt
    63721 ctgatgatta tatggatgtg cttgctgatg gcatatggca aaactttttt gaagaaaaac
    63781 cagagcctct aactggagaa ggaaaaagag catggcttaa aactttaaca ggagtagcac
    63841 ttggttcaga tgcatttttc ccatttggag ataatataga acgtgcaaaa agaagtgggg
    63901 taagttttat agcacaacca ggtggttcta ttcgtgatga taatgttata ttaacttgta
    63961 ataagtataa catagtcatg gcatttacta aaaatagatt attccatcat taaaatactg
    64021 aaagtataaa gataatatag attaagtaaa aatctacaac aagttttgtt gtagattttt
    64081 ttatttgctg tataatttta aatagaactt tatttttaga tattcaattt ggaggttgat
    64141 atggctttaa atataagaaa ctatagccta ttatgtaatc aaggaacagc taaatttaat
    64201 gaagatgtag tcggtataaa tccatttggg gcatgggttt tagatggtgc tacaggactt
    64261 aatggaaaaa atttagtgtc aaatgaaagt gacgcaaggt ggtatgttca gtggtggaat
    64321 aggtatttat ataaaaatat aaataaagaa gaatcattaa agagtattat taatactgga
    64381 ataatagaag taaaaaaaga gtatgaacta agattaaatg ggtttaaggt tgaaaaatta
    64441 gatttaccat ctagttctat agttgttgta aaatttcatg aaaataaagt agagtatttt
    64501 ttattaggag attgtgcttt gtttattaaa aatggagatt ccaaagttat aaaagatagg
    64561 agtatttgta aatttgataa tactgtattt gatgaaatga gtaaactttc taacttggaa
    64621 gagatggcat ttgatgagat tagaactagt gttatggata caatagtaag caatagattg
    64681 aagaaaaata cgaaagaggg ctattggata ttggattttg atgaggaagc tgtggaaaat
    64741 tctatatatg gatacattga aataaaaaaa gattttcaat tgatgctaac gagtgatggt
    64801 tttacaagtg catgtgatag atataatcta ataaaagaag aagaattgat acgtatagca
    64861 gaaaaatttg gtataggata tatacataat aaagtaaggg attttgaaga taatgactat
    64921 aaagcggtta aagtgccaag atttaaaata aaagatgatt catcttgttt atatttagat
    64981 atatataatg attagactgt ataaaactat ttaattttag aaaggaggca agtgaaaagt
    65041 gaaaattctt catataataa cacaaaaacc aaatagtaca ggtagtggta tatatttgtc
    65101 tggtatgata aaagggttcg aaaaaatcgg tcataagcaa gctgtaattg caggtataga
    65161 tgtaaatgat gatgtaaatt gttttccaag tgaagtaagt ttttatccag taaagtataa
    65221 ttgtggggag ttaaattttc ctgttgtagg tatgagtgat tctatgccat atgaaagtac
    65281 aagatataaa gatttaaata tagacatgat aaatagattg aaatatcaat ttaaagtaaa
    65341 tatagataag gctatgaatg attttaaacc agaacttata atatgtcatc atttgtacct
    65401 cttaactgca tttgttaggg aaatagtaaa agatataaag gttatgtcta tttgtcatgg
    65461 aacttgttta agacagttaa ataccattga tttagagaaa gaatacataa tagcaaatat
    65521 aaggaaatta gatttaatat ttgctcttca tgaaaatcag aaatatgata ttataaagac
    65581 ttttggagta agtgaaagta aagtagttgt aattggtagt ggttataatg atgatatatt
    65641 ttataataaa aattataaaa taaaggatga taaaataaaa atagtatttg caggtaagat
    65701 atgtaaatca aagggattga ttccatttat aaaatctata tctaaattaa aatatagtaa
    65761 agatttaata gaagtcaatt ttgcaggtac tggaagcgat atcgaatcat ataatgagat
    65821 agttaaactg gcaagtaagt ctccatttaa aatgaatttc ctaggaaagt tagaacagag
    65881 agatttagct gagctattca acaggtcaca aatatttgtg ttaccatcat tttatgaggg
    65941 attaccagtt gtagttttag aagctttatc ttgtggcaca gatgtaatca ctactgatat
    66001 tcttggtgtt aaagagtgga ttggtagtga gattaataat tctggaaaga tagaatatat
    66061 ttctctacct tttatggaga aagaaggtat tccaaaagat gaagagttat atgattttga
    66121 aaataatttg tataatgcaa tagattctaa gatacaatct ttattgaata actcaaatga
    66181 gaaaacatct gtagatatgt caaaaaaaac gtgggatggc ttagcatata gaataaatga
    66241 agttatttta atggatgaat tgtgtttagt ctaaaattat ttaaattata aaaaagtgta
    66301 actattttta aacttttttt aaatgatttt atattatact aatactaaat atatttgttt
    66361 tagggaggta atttatgagg attagtaaaa aggtattggc gttaggtatt tcagcattac
    66421 tgttaagtgt tagttttcca acatcaataa acgcactaga taagattgaa aatattcaag
    66481 gagtagataa atatgaaaca gctgggctta tttcagataa gcaagatttt acaacagcag
    66541 ttcttatcaa tgcagattct acaatggtag atgggattgc tgcaagtggt cttgcaggag
    66601 taaataatgc agctatttta ttaactaata aggatgatat accagaagca acacttcaaa
    66661 gactgaatag agttactaag atatatgtaa taggtggaga aaattctata agtaaagatg
    66721 tagaaaaaat gttacttatg agaagaatgc aagttataag aattgatggt gtagatagag
    66781 tagatacaag ttataaaatt gcaggtgaaa tagaaaaaat taaaaacagt gataagatgt
    66841 ttttagtaaa tggatttaag gatgaagctg atgcagtaag tgttgcatct gttgcttata
    66901 gagatggagc tcctataata ttgacaaaag atataccttc agcagaagaa gacacagact
    66961 tagacccatg gtttggagtt tctcctgttc cagtatatgc tattggagga gagtctacat
    67021 taagtgatta catagtgagc agatatagag caactagaat tggcggtgtt gatagatatc
    67081 aaactaataa aaatgttatt gaaaagttct ataatggagc aaaagagttc tatataacaa
    67141 gtggagacga tttagtttat gctttagttg catcaccact tgcaaaaaat gctcctgttg
    67201 ttttagtttc aaataaaagt gataagagta tattaagtgg agctagtaaa gtaacagcaa
    67261 taggtataag tgataagagt attatagagc aatgtttgga tgctgtaaag aagtaatgga
    67321 gtgttattag taaaatgaat atatacattg aaaattagta gattgttcat tttataatgg
    67381 tataaaatat atgggaagag gctatcaaat ggagataagc ctctttttta ttgataaaat
    67441 tatgaaaata tactttattt tatataaaaa aagtatctca tgaactaaat gtctattttg
    67501 atatactatc tccttttctt atattatatg tattatatga ttttttatat ggaataaatt
    67561 tcataagtat tatcttcctt taatttttct aaccaaatca tctctaaaat atctagttct
    67621 tctaaatagt ctttctctgt tttgttatca tcatgtttta taagttctaa aacttcaaat
    67681 gtaaatgctt tttcaccata ttttttccat tcattattta attcttttat catacatgag
    67741 ccagcaccaa gctgaaattt gagagagtta aatttgcttt ttatgtcatt actttttcca
    67801 aggtaaatct ttttagtaat atcatttttt attatgaata cacctgtgtc aaatttcatt
    67861 tctttgtata attgttttaa ttcacgtttt ctatccatga ttttagatac ctctctttat
    67921 aattgatatg taatatgtaa gtttaaaaat atattacata tcaattataa agagattaat
    67981 tttatatgta aatagttttt ataaatttaa ttatgaatta gtcatcaata aacaagaaat
    68041 ttagctgtag aaatccatta taaaggctat tataaatttt aatatgctaa aaatataaaa
    68101 agaatagttg acagtataga aaatatggaa taaactaaaa gtgtaatagt aatacgaaat
    68161 tatatattac attgaaaggt gtgaatgatt attatgaata aaaaaataga attaataggg
    68221 aattttgcaa gtgattggat taggtatagt gattatgaat ataaaattac tgaagaagat
    68281 gaattatata tagttccaac agaagatgct gtgtttacca tgtataaccc atttgatgta
    68341 gcagatgata taatagtaga tataattcgc ataggacaag aggcattaca agatatatca
    68401 aaagagacaa aagaaatgaa actaaagaaa gaagtacttg aatttgtaaa aaagtatgga
    68461 ttattgggtt taatatattc aagtgtatat aatagagata tagttggaga agaaagagta
    68521 ctgatgattg aaaagaatta tattacaaaa gagaatatat tgagtacaga tgaatatgta
    68581 aacatgttta taccatttgc aagtgatgaa gatgtgtatt ttaaaaaata tagaaggggt
    68641 atagatgtat caaagagaga agaatctcca aagttttttg gaaagagacc attgatttta
    68701 gatttagtat tttcaaagtt ctacactgaa caactagatt ggattgtaag ttttgctaaa
    68761 gatatgtgta agcattttaa tcaaatttgt gtatataaaa atacatctaa tctattaact
    68821 gaaagtgtta ctattatgtc tggagggttt aatcctcaaa agataggatt ttctataagc
    68881 caattagata aaccaattat tgcatgggag tttgattctt tgaaaacagc tattgagact
    68941 atctatgcct ttgcaattac aagtgaacct tcttctttaa ataaatgcaa gtactgtggt
    69001 aaaatttata ttcctacaaa ttctaaatct caatactgtt caccttcttg tagaaattgc
    69061 tcaaatgtaa agaaaagtag aagtagagcc aaaaaagata aataaaatta ataaatatat
    69121 cattgtttag attttagtaa ataactactg aattaaaagt tgttatagaa aattatatat
    69181 ctaaatgatg gtattttttt gttgagaaaa ttgaaaagtt taattgagat agtaattttg
    69241 agttgacaaa aaccactttt aacactacta ttataagtgg ttggtaaaat aatatacact
    69301 aatttaaata tagcataaaa aacaaaaaaa gtcaatgaaa aaaataaaaa aggagaattt
    69361 aaaaatgata tcacctatta ttttgagttc tataaatcag aatttaaagg aaatagaaag
    69421 aaatgaactg cttgaaacta atatagaatc tggagattat ggtctagctc tttctgaatc
    69481 tgatgtaaaa gatataataa attcgagaga taatacttta aaggggtatg gaagaataga
    69541 attagatata aaagttacaa aacagttaat agaaaatata tatacatcac aatatacaaa
    69601 tgtggacaat tatttagagg ctattaatga tatgcaagaa attttttatt atttaaaaaa
    69661 tgaaactgat gacaagatat gtgatgatga gattatagaa atactgggtg aattttatga
    69721 aaaattttca ggcaatatgg acaatgtaag aggagaagca gacgaatttg caaagaaatt
    69781 taaatttgga gaagtttaat atatgatagg agagattttg tatgttaaat aatttaagta
    69841 atattaatat aaacgaaaat aatttaataa agaaccaata ttccatatct ctacttaagg
    69901 aatgtctaaa ttgtaaagtg atagatgaaa gagaagtata taatatacaa caagaaatat
    69961 ctctaatact tatggatttg attaaaaaat atacaaatgg tcaaagcaca tcagtaaaaa
    70021 cagaagttgc cgaaaaactg ttgatttcaa tatggtatgc tattgatgca tatataaata
    70081 agcttggaga tatagaaaaa agagttgtgg agttgactgc taagaatgtt aaaaaagtgt
    70141 accttggagg cattgaaata ttagaggaag agttagttag gctgaaagat ttttataaac
    70201 taatgatgag tagaaaattg gatactaatt caatagcata taatgatacc ttgatggagt
    70261 tatcaagttt ctttaaaagt tatattgtaa aatttgaagc tcaggacgtt ccagtaagta
    70321 tagattatcc attggcacta gatgatatgg atgttaaggg tatttattat gtgaagaatt
    70381 atattgagag tatagatata gaaaatagat tttgtaacct atttaagaaa aaagatagag
    70441 aaaaattatt ttatgactat ggggtgattt ataaaataga ttgtgatgtt atacttgtaa
    70501 atttatttga acttattata aataattgta ttttttctac tattttagga aatgaagtga
    70561 ttaatttaga aatttcaaaa tatgagtatg aatttttaga aaaacaattt aaaaatatgt
    70621 acaataatat tactgaagat aaagttatag gctctgaaga aagtaatata attgaattga
    70681 ttgaagtaga tgatagtttt aacactgaag tagatagtaa tttggattat aatgattttg
    70741 aagaaattaa cagagaaatt agaataaata aaaaaataac tttactactt atggaagcaa
    70801 ttgaagtatt aataaaaaga ttaagcatag aagatgaaga tgtaataaga tatattaaaa
    70861 aatatgaaaa gatatttatt gaatctgtgc taagctcaat aaaaagtaac acttttaaaa
    70921 gtatggtaac tgtgagtaaa aataaaaatg aacacttaga agactatatt gttgatgatg
    70981 aaagtaaatt ggatgatgaa tcgtttagag agatattcaa tgagatatta gatagtacat
    71041 ctataattga aaaaataaga ataataaagg aaaatatcaa tgctaaaaaa gactttatcg
    71101 atattcttga atctgaatgt ttatttggag aagagtattt aatgttgttt gcatcattaa
    71161 gtgaattaga attggcaata ttgggtagtg tagtatttta tgaagatatt agaatgagag
    71221 aaattaatat attagaattt atgttaaatg agaaaactga aactacttta tggaagacag
    71281 agtacattaa atttatgaag aggcaaagtg aagataagat atactccata gaagagcata
    71341 tgaataaaat taattaacaa aaaattgtga ataaatagaa tgttagtata taatataatc
    71401 tgtaaagcat atcaaaaata catatatttg gaggaaaatt atgaaagagt atatcataaa
    71461 taatgttgaa gaaataagag aagaattaat tgatttatct aagaaaatat gggaaaatcc
    71521 agaattagcc tttgaagaaa agtatgcaag tagcattcaa aaagaatacc taaagtcaaa
    71581 aggatttaaa attgaagaag tagaaaattt acctactgga tttatagcaa gttttggaga
    71641 gggtaaacct gtgattggca tacttggaga atatgatgct ttaccagagc tatcacaatg
    71701 tgtgagtgca gaaagaaagc cattggtaga aggaaaagct ggacatggat gtgggcataa
    71761 cctgttgggt gtagcaggtg taggagcagt tgtttctata aaaaaattaa tagaagaaaa
    71821 taaatttaat ggaacaataa aatattttgg ttgtcctgct gaagaagaag gtggaggaaa
    71881 gacagttatg tgtataaatg gctgttttga tgatgtagat tgtgcattta catggcatcc
    71941 ttttgatata aatgcacctt ggagaggtgg aagtctggca aacttatctg taaaatttaa
    72001 atttaaaggg ataacagccc atgcagctca agctcctcat aatggtagaa gcgcacttga
    72061 tgctgttgaa attatgaatg ttggagctaa ttatttgaga gaacatgtta ttgactctat
    72121 aagaatgcac tatgttataa ctaatggtgg tggaagacct aatgtagttc ctggatttgc
    72181 tgaaagttgg tactttatta gaggtaaaaa agcaagggat gcagaacatg ttcttgatag
    72241 attaataaaa gtagctcaag gagcagcaat gatgacagaa actgaaatgg agtataaggt
    72301 tacagatgga atatatgact atataccaaa ccaatgtttg actgatttag tttatgacaa
    72361 tatggttttt gttggttgcc ctaaaaatac tcctgaagaa gaagaatttg caaaaaaatt
    72421 gtgtgatact cttactagag aagaaagatt aggtgtagca acatcattac aaaatgataa
    72481 atctattgta gaaagttata tacacaagga aatagttgac ggtgacaaag ataaaggact
    72541 agctggttct actgatgttg gagatgtaag ttatgtaata ccagtggctc aatttgcaat
    72601 ggcagcttgg cctgttggaa ttgcaagtca tacatggcag tcatgttcat cagcaggttc
    72661 aaatatagga ttttctgcta tgataaattc agctaaagta ctggcttgta gtgcttatga
    72721 tgtatttatg aatactaaaa ttattgatga agcaaaaatt gaatttgata aatcattaga
    72781 tggacaaaaa tttaaaccat tggtataatt ttggtaataa aatatttctg gggggaatag
    72841 ctatgagaga aaaagttgaa aaagtgcttg aggaaaagat aaaaccagta ttacaaagag
    72901 atggtggaga tgtagagctt atagatgtaa atgaaaatgg tgtggtttta gttagactac
    72961 aaggggcatg tagtgggtgt ccaggagcga ctatgacaat caaagctatt attgaaaatg
    73021 ttttggtgag tgaagttcca ggagtaactc aagtattagg tgtttaatag ttagcgttta
    73081 ttaaatgtat gttatacata agtatttaat aaagaagtaa aaaaaatagt gaagcaatat
    73141 atatgaaaaa gtatgataaa gataataaaa cattatagaa ataatgaaat atttcatatg
    73201 tatatgaaga aataagaaaa aatagtgaag caatatatat atgaaaaagt atgataaaga
    73261 taataaaaca tttatagaaa taatggaata tttcatatat acatatgaaa aaatagtaaa
    73321 acaatatata tatgaaaaag tgtgagaaaa taataaaata ctatagaaac aattaaatat
    73381 tctatatagg tattaagaaa catgaaagaa ataatggagt attatagata aatatgtaaa
    73441 agtgtgaaag aaggatgtag ataaatttgt cttatacaaa tttacctaca gtatttctta
    73501 cacacttttt attttactat ccaaccatac caataaacat acctataaag tatggaacta
    73561 accatatagt ccatacaact atactaaact tatgaaagaa ttttttcttt tcctcatcat
    73621 ctttgtatag gacaaaagta gcccaacttg catgaaaaag cataagcaca attgcaagaa
    73681 gacctgtaat actatgaagg ttttgtgata aagcagattt tacttcaaaa gtatggctgt
    73741 tggctatgtt actcattgta aatgttccta aagtatcaaa tataaaccca agccaaaata
    73801 taattacatg tttctttttt aaaatttttg cctttctttc tccaaataca cctatagtgt
    73861 agaaaattaa agctgatgtt ataaatacta ttgcaagtat taatttataa ttcataatta
    73921 tctctccttt acttttgcca atatatttct aagatttttt actaagtcac tcaattcgtt
    73981 ttcatcacaa tttttaaaaa tatcatcaaa actttcttgc attttaattt taaaatttgt
    74041 ggcaaattca aatcctgttg ttgtaaactt aacgtatgta tttcttttat cattagattt
    74101 cttgaatttt tctatatatc caatctgttc taatctgctg attatgcctg aaaccgtacc
    74161 tttagctaaa gacatttcat cacatagttg tgatattgta agttcttgat tatgagctac
    74221 cagttttata actataatct gttggtgtgt taatccattt tctttaaaat tttcttctac
    74281 tgtgtacata gttttagaat aaagttcttt taagagcatg gctattctaa aacagtcata
    74341 attacttttc aataaaatca cctcttaaat ggtttgcata caaactaata taatatactt
    74401 ttcttatata gtcaacctaa aattttataa ttttatagaa aataatgaag aatagaacat
    74461 aaaaatttta ttttaggtat aaataaaata atttgatgaa attttaacaa tttttaaaaa
    74521 gtttgtttac acagttaata aatgatgcta aaattaactc atagataaat atagaaaatt
    74581 taattttgtt taatgataat ggaaccacga aggttttaac gttactttac gtttgctttt
    74641 atgtggtttt tttattgcaa caaagggggg ttggggtttg ttaaaggata tactgaaaaa
    74701 gttgttgcag tttattttag taatgttttt attatctttt attgtttttt acatggcaag
    74761 acttgctcca ggagacccat taatctctta ctatggggat ggagtagaaa gaatgagtac
    74821 acaagaaaaa gaaaatgcta tgaaaaaact tggtttgaat gaaccaatat acagtcaata
    74881 tataaaatgg atttcaaatg catcaaaagg ggaatttgga atttcattta aatataaaca
    74941 aaatgttact tctgttataa atgatgtcta tataaacact ataatattag gtggttcagg
    75001 gtatatactt acctttgtgc tagccttatt gttaggaata ttttgtacat tacatgaaga
    75061 taagctcatt gatagaatca tatgcaaatt aggaacaata accaactgta ttccatcatt
    75121 ttgggttgcc ttagtactca tacttatatt tagtataaac ttaagtatac ttccaagtag
    75181 tggtgcttat tcaatgggag aagagtccag tatattaagt aggatatcac atctaatctt
    75241 acctcttaca gtacttatat taagccatct atggtattac acatatatga taagaaataa
    75301 attactagag gaaataagag aagattatgt gcttttatgt aaagcaaaag gtttaaataa
    75361 tagaactatt gtttttaagc attgcctgag aaatataatg ccatcatata ttagtataat
    75421 ggccatttcg atacctcata tactaggagg aacttatgta gttgaaaaag ttttttctta
    75481 tcctgggtta ggaacacttt gttttgaaag tgcaaagtat catgattata atatgttatt
    75541 agttttatgc ttaataacag gggctttagt agtatttggg aatatgttag ctcaaattat
    75601 aaacaataaa atagacccta gaatgaaata tgatagaggt gatactaatg aagccacaat
    75661 atagtgattt tgaaattgta ggagaaaatt atattttagt agcagaagat gaacatatag
    75721 aaacaaagaa aaccttatct aaaaaaatta aagaattacc atatatatca attattattt
    75781 tatcaatcat agtcattgga agtgtattct catcttttat aatgacacat gaaccaacat
    75841 acatggattt agcaagttct aatttagctc caaataaaac ttttttattt ggaacagact
    75901 caatgggtag agatatatat tctatgatat ggtatggagg aaaaatatct ttatttatag
    75961 gactattttc cactgtaata tcaactgtta taggaattgt ttatggtagt ataagtggtt
    76021 cagcatctga actcgtagat gatgcaatga tgaggtttac agaaatcata cttagtatac
    76081 cttcaatatt aattataata tttgtacaag ctatacttgg aaattcaaat ccagtatcta
    76141 tgtccatagt aatagggata acaagttgga tgaatatatc taagatagtg agaacagaag
    76201 ttagacaaat aagaaatagc gaatacatac tagcagctaa gagcatggga ggaggattct
    76261 tctatgtatt aaagcaacat ttacttccaa attttgtggc atcaataatg ttcatggttg
    76321 taacaaacat aggcgcagct attggtactg aatcgacact tagcttttta ggaattggtt
    76381 taccaataga aattgtttct tggggaagta tgttatcttt gtcagaggaa gcattacttt
    76441 caaatagatg gtggattata ctgattccgg gtatattttt ggttaccaca ttggtgtgta
    76501 taacaaatat aggtaattat ataagaaaga ataataataa aaaatctagt aatttataaa
    76561 tcagcatttg agtactaaat aagcaaatac tgaggtattt gaaatatcta tttaaataaa
    76621 tggggtcaaa gctttgaaaa atattttata aaaagcaaaa gggggagcat catgaaatta
    76681 aagaagttaa aagttttaag tttagtaatg atacttagtc taatggcagg ttgttctagt
    76741 ggaggagaca aagataagaa ggcagatacg cctaaagatg gaaaggtact tgtttatgga
    76801 agtaatgact atacaagtat aaatcctgca ctatatgaac atggagaaat aaattcatta
    76861 atatttaatg gattaacagc tcatgatgaa aataataagg tggttccttg tctagcaaag
    76921 gactggaaat ttgatgaggc aacaaataca tatactttta atttaagaga tgatgttaag
    76981 tggcatgatg gagagaaatt tacggcaaat gatgttaagt ttacaataga aactataatg
    77041 aatccagata atgcttctga gatagcatca aattatgaag atataacaaa aattgatgtg
    77101 gttaatgata atactataaa aattacttta aaagctccaa atacagcaat gcttgattat
    77161 ttaacagtag gagtattacc aaaacatgtt ttggaaggta aggatatagc tactgatgaa
    77221 tttaatcaaa aaccaatagg tactggacca tttaaacttg aaaaatggga caaaggtcaa
    77281 agtataacac ttgttaagaa tagtgattat tttgtaaaag aaccaggatt agataaagta
    77341 gtctttaaga ttgttccaga tgataaggct aaggcaatgc aattaaaatc aggagaatta
    77401 gacttagctc aaataactcc taaagatatg tctaactttg aaaaagacga aaagaatttt
    77461 aaagtaaata taatgaaaac agccgactat agaggtatat tatacaattt taattctaaa
    77521 ttctttaaag ataaaaaagc taaaggatta ccaaatgctt taagctatgc aatagataga
    77581 aaagcaatag ttgacagtgt attattagga catggtgtac cagcatattc acctttacaa
    77641 atgggaccat ataataatcc tgatatagaa aagtttgaat ataatccaga aaaagctaaa
    77701 caagaaattg aaaagctagg ttggaaatta ggttctgatg gaatctatga aaaagaaggt
    77761 actaagttag ctttcgagat aacagcaggt gagagtgacc aagttagagt tgatatggct
    77821 aaaatatgtg cacaacagtt aaaagaaatt ggtgttgatg ctaaagctgt tgttgtaact
    77881 gaaacagatt gggctaatca agatgctcat ttaataggtt ggggaagtcc atttgaccca
    77941 gatgaccata catataaagt atttggaaca gataaaggtg caaattacag tgcttactct
    78001 aatcctacta tagataaaat acttcaaaaa gcaagagaaa cagaagataa agatgaaaaa
    78061 ttaaagttat ataaacaatt ccaagtagaa atgactaagg atatgcctta tacatttatt
    78121 gcttatatag atgcaatata tgttggaaaa ccaaacataa aaggattaac acctgataca
    78181 gttttaggtc atcatggtgt aggtatattc tggaacatag ctgactggac aattgaataa
    78241 tactgaaatt aattagaaac cttagggata aaaatatatc cctaaggttt gaatagcata
    78301 ggggttgatg gtttttggaa catttattgg aggttaataa tctatctgta agttttaaag
    78361 tagaagaagg agaagttcag gctgtaagaa atgtatcttt taatctaaaa aaaggtgaga
    78421 cattggctat agttggagaa tctggttgtg ggaaatctgt actgtgtaag agtttgatga
    78481 ggatactccc atacaatgga tatattaaaa atggagaggt tttacttaaa tcaagtgatt
    78541 tggttaagaa gtctgaaaaa gagatggaag atataagagg aaagaatata tcaatgatat
    78601 ttcaagaccc tatgacatct ctcaatccaa ctatatcaat aggaaagcaa attgcagaag
    78661 ctgtaatcat tcatcaaggt ataagtaaaa gtgaagcaaa aaagagagcc atagagctta
    78721 ttgaattggt tggaattgat aatcctgaga aaagatttaa acaatttcca catcattttt
    78781 caggtggaat gagacaacgt atagtaatag ctatagcact tgcctgtaat ccagatgtat
    78841 tgattgctga tgaacctaca actgctttag atgtaactat acaagctcaa ataattgatt
    78901 taataaagga tttacaacat aaaataggtt tgtcaataat atttataact catgatttag
    78961 gagtagttgc aactatagct gatagaatag cagttatgta tgcaggaaag attgtagaaa
    79021 taggaactgt agaggatata ttttatgacc ctagacatcc atatacttgg gggttgttgg
    79081 gttcattacc tactttagat tcacaggatg aatatttata taatatacct ggaatgcctc
    79141 caaatttatt gaacccacca aaaggagatg cttttgcaat aagaaataaa aatgcactta
    79201 agatagatta tgaaaaagag ccaccaatgt ttaaaattaa tgatacacat agtgcagcaa
    79261 cttggttatt gcacccagat gcacctgaag tagatgtacc agttagagta aattgtggaa
    79321 gggtgatttc taatgaatag agaaaaaata ctggaaataa aaaacttaaa gcaatatttt
    79381 catttggaca aaagtactac tgtaaaagca gttgatgata taagttttga tatatataag
    79441 ggtgagatat ttggattggt aggagagtcg ggttcaggaa aatctacaac tggtaaaact
    79501 ataataagac tacatgaatc tactggtgga gaagtaattt acaaaggaaa ttgcatatca
    79561 gataaaaaaa cgtacaaatt tataaaaaaa gatgtaaaca aaagtatgca gattattttt
    79621 caagattcta cttcatcatt aaatccacgt atgacaattg cagatataat ttcagagcca
    79681 ctaaaaattc aaggtatctg taaaaataaa acagatagaa tgaataaagt atatgagatg
    79741 ctaaagctag taggacttga tagaagttat gcaaataagt atccatctga tttttcaggt
    79801 ggacaaagac agcgtattgg catagcacga gctctttcag tagacccaga atttataata
    79861 gctgatgagc ctatagcttc tttggatgtg tctatacaag cacaaatagt aaatttattt
    79921 aaaaaattgc aacaagaaaa gaatttaact tgtttattta tagctcatga tttatctatg
    79981 gtgagacata ttagtgaccg tataggagtt atgtataatg gaaaattagt agaattggca
    80041 gattcaaatg aattgtataa taatcctatt catccatata caaaatcact actttctgca
    80101 attcctgttc ctgaccctag atatgctaag tcaagaaata gaatagagta taattctaat
    80161 ggatatgatt gttcaaatga aaagtcatta agttggattg aggtttcaga tggacatttt
    80221 gtatattctt ctaaatcaga aataaataaa tatcaacaaa atttaaaagt tgtttagtat
    80281 aaaaatactt gaacaggtat ttatttgaaa tacaaactaa aaccctattt ttggagaaat
    80341 tttaaaacta ctccaaaata gggtttttta tttctacttt tcaaatataa taaattcaaa
    80401 tataataaaa ttaaaaacaa gtaaagtatg ttgttaagaa agtgctataa aattaaaaat
    80461 agtaatgtag aaaaaatgag caataatctt attttttcta caataatttt ctataattta
    80521 aagtaaggaa agtttgataa attataacct tagttaaaga ataagagttt attaaaaaat
    80581 aaagtgtgta taggggtttt agttaataaa atattataat gtaggggagc ttgtaatgat
    80641 atataaaaaa gataaagtaa tgaaagtttt agaatcatca tatagggaaa atgaaaaagg
    80701 gattacagct aaccaattat cagaaaagac aggaattgca agaaacaata taagtacata
    80761 tttaaaccaa ttattcaatg agggtatggt tacgaagata aaaggaagac ctgtgtatta
    80821 tatccctgca aatcttaacc ttaacaagaa tgaattgctt gatacacaaa gtgagttgct
    80881 tggcataaaa aaaggaacaa aagtagaaaa caaaataaaa aaagatagtt ttgaaacact
    80941 aataggtaaa gaacatagtt taagacctat aatagaaaaa tgcaaggtcg caatgctcta
    81001 tcctacaaat ggacttcata ctattatcta tggagaaaca ggagtaggaa agagtatgat
    81061 tgctagatat atgtacgatt attctataga tagtggaatt agaaaaaata aagctccttt
    81121 tgtaacattt aattgtgctg attatgctaa taatgcacaa ttacttatgg gacatatttt
    81181 tggagtagaa caaggagctt atacaggtgc agaatcttcc agaaaaggtc ttttggaaat
    81241 tgcaaatgga gggatactat ttttagatga aattcataga ctaccagcag aaggtcaaga
    81301 aatgttgttt acttttatag ataagggaac atttaaaaga ctaggagatg caacgaaaga
    81361 aagagattct aaggtattaa taatatgtgc tactacagaa aatccgacat caacactatt
    81421 agatacattc aatagaagaa taccaatgaa aatagaaata ccatcactga gagataggac
    81481 aatgattgaa agaatggaat tagtcaaaaa ttttttcaag gaagaatcaa aaagtatttc
    81541 tatttcaata aaagtacata aagaaataat taaatcacta ttactttatg attgtaaaaa
    81601 taatgtaggt caacttcaaa atgatataaa attagctgtt gcaaatggat acctaagata
    81661 taaaagagat aataaagaac cagtttatat agagaaaaaa tattttgata aatctataaa
    81721 tgaagtgagt gatgattata gagagaagtc tattaaagca gatgaagtta taacacatgg
    81781 aatagaatat tttgtattta cgtcattagg agaagaagaa gttattaact acaatgatat
    81841 aaatattatt aatgcagtaa atactaatct taataaatct gtagaaatga atatagcaga
    81901 tgcttctcta tttaataatg ttaagtttaa aagcatgtgt gaatcaataa gacaaattat
    81961 taaagaagat gaagaaatag atataagtga atcaatattt aagtcaatgg caatttatat
    82021 aaaaagcgta ttggataaaa gtagctctac aaacaacata gatttgaatc aaattagaag
    82081 aaataacaga agtgaattta aaacagcact aaaaatagtt ggaataattg aaaatgaatt
    82141 tgatttattt ttatctatag aaactgtagc atatattaca ttattcatag tacaagctaa
    82201 acaagatgaa caaaataaaa tagtgaataa cattaatatt atagttgcta tgcatggaga
    82261 aactacagca agtaatggta aaagcagttg gtgatattat tggaaagtgc agtgctattt
    82321 ctttcgatat gaagttagat aaaagctatg atgaagttat tgtagatttt aaaaatttaa
    82381 ttaataatat agacaataaa gatgtattac tatttacaga tatgggttca ttaaactcct
    82441 ttgatgaaat tataaagaaa gaaaaaaagt gtgaagtaag agtaattcct atggtgacga
    82501 cattaactgt gttagaagca gttcagaagg ccaatatggg attaccttta aatgacgtat
    82561 acaactctat cactaacacg agaaagtatt attttggaac taatgaaatt caaaataaag
    82621 aaaatctgtc taaaacaatt attatagcat cacatgtttc agaaggtgta gataataaaa
    82681 caagaaaaat attagaagaa aagatgagta ggtacttaga tggaatagat attatatctg
    82741 tcccatataa aacagaaaaa gatttaagtt taaatattac aaaacttaaa gaaagtagta
    82801 atattgttgc agtaatcaat gaacaaagaa ttaatattag aggaattgac tatattagca
    82861 aaaaagatat agataaggat gaaaatatca ataaattaaa aaatattata aagataagta
    82921 taggttatga tgatgtagtt gaaggtttaa agacatcctt aaaaagctct aattataata
    82981 ggatatttaa agatataaaa tatgtgtctg atgaattgtt tttagtattt aatatagaaa
    83041 agaaatacga taaagtaatt ggacttatga tgcatttagc tttcatggta gatgggttga
    83101 ttggaaatac tagagaaatt gaaaagcttg ataaagaaaa aacacttgat tatcacaaga
    83161 gcctaagcaa aataaaagat atagtatctc aattagataa aaaatataat atagaaatta
    83221 atgaaaaaga gtgctatcaa atattattaa tattagaata tgcagaaata atcgaaaaag
    83281 attaccaatg agtataaaaa cttatttggt aatttttttt agtctaaaat aatattaata
    83341 ttagacacat ataaatatac ttagacaaag tatctaagtt ttgatgataa aaatgattga
    83401 aataacagtg ttttaaagtg tctaaaaaaa ctggcataat acttgcttat attattaaat
    83461 gagtaatata aataattaaa atttaaataa aaaggagtaa ataatatgca agataaaata
    83521 ttaagagata aaaaggcaaa tgacccatgg gcaagaatga ctacaagaaa cggatttagt
    83581 gcagacgaaa taatatcgtc atttcaaaaa gctataagaa gaaatatggt ggaagaagct
    83641 tgtgaatttg cttatgaact atatatatca tcaccagaat tagaagataa gctatggaga
    83701 aggatactta caatatcagt tgaagatata ggaatggggg acccatcagc tgtaataatc
    83761 ataaataatt taaatcaagt aagaaaggaa tattcatatg cagatggaga cagaccttta
    83821 tttttcatac atgcaataag atatctttgt gcatgtgaga aagatagatc aagtgattta
    83881 ttaaaaaata taattataaa aggatttgca atgggtaaag ttccagaagt tatggacgtg
    83941 gcacttgaca agcatacata tagaggatta gaaatgggaa gggattcatt ccacttttta
    84001 aatgaagcta gtatagtaat accagaaaaa gaagtagata atgattataa agaaagatac
    84061 ttaaaaatat tagaaaaata taagcaagaa gaagttatag atacggcttt caagtttaat
    84121 cattggcagt actaagaatt agagtaaata ttaataagaa ttaaaataaa ataataagaa
    84181 ttaaagtaaa aactgatagg aattagagta agaattggct gataaaaaat tagaaaataa
    84241 aagaggttag atattgtagg agggtaatta tgaatatttt attagtatgt gcaaatggag
    84301 cttcaacagg tgtacttgtg gaaaagatga aaagtttttg tagtgagcat gaaaagttaa
    84361 aaactaaaac tataaatata gaggcaacat cattcgaaaa tttaaaatca tacattgaag
    84421 ctaatgatac agatgtagta cttgtagcac cacaaattag gttcaaggaa gatgatgtag
    84481 ttgaagcttg taagaattac aaaatagcag ttggtttaat agatactaag cattatggtc
    84541 gtatggatgc tccttctgtt atgaagtcgg caatcgaatt atataaaaat agataattgg
    84601 ggggaataaa aatggaagca cttcaaaata atttaagaag atttcttcta ccaatagcac
    84661 aaaagattga aaaacaaagg catcttcaag ctataaaaga aggtatgata agcattaccc
    84721 caataataat tgttggttct ttaagtatgt tatttatggc attaaacaat atgttacctg
    84781 aaggaagtgc aaaaacatta ttatctgaaa atatggatac attacttatc cctaataaat
    84841 ttactatgag tttattatct atatattcag cattttttat agctcaggca ctagctaaaa
    84901 aatataatct taatcatgta gaaataggta tgacagcagt tgttgcacaa cttgttgtat
    84961 gtggacaagt agtagatggt gtattagata caagttattt agatgcacaa ggtttatttg
    85021 taagtatatt agtagcactt ttagtagttg atattactaa gtttatgaat gataaaaatc
    85081 tcgtaattag atttccaaaa gaagtaccta gtgtagtaaa taaaagtttt agaaatttaa
    85141 ctccaatgat agtatgtata atgttattta cagcaatagc agcaataact aaaaatgtct
    85201 caggtcaacc attaccagct attataatga atttcttagc accagctata agcagtgtag
    85261 ataatgtttt tgcagtaact ataatactat ttataactca attattatgg ttctttggcc
    85321 ttcatggagc agcaataact tcaagtatat ggatgccaat agcagctaca tatatggcag
    85381 aaaatgcaac actgatagca gcaggaggag acccaaaata tgtgtttaca ataggatttt
    85441 actatggttt cttgcaagta actggttcag ggataacttt gggattagtg taccttatgt
    85501 caagaagtaa gtgtaagagt tttaatagta tgggaaaagt tgtgatttta ccatcactat
    85561 ttggaataaa tgagccagta atatttggaa caccaatagt tatgaaccca tatatgtttg
    85621 taccatttgt atttggacct gtattggttg gagcacttaa ttttatggca ttaaaagtag
    85681 gattagtagg attacctatt gcagaaccac caggcttttt acctccaggg gttgcagcat
    85741 ttttgatgac attagattgg aaggcaatcg tattagtatt tgcaagtata atacttatga
    85801 ccttgatata ttatccattc tttaagataa tggagaagga agaattaaat aaaaatgcag
    85861 aattagctac aacattagat gatgatagct ttgattttta acaagtcatt agaaggagaa
    85921 ggatatggta cctgaaatgg aagaaaaagt atttagtata atatcagaag caggagatgc
    85981 taaaagtgat gtaatgatgt ctcttaagga aataaaaaaa ggtgactaca ataaagcaaa
    86041 acacctttta aattcagcct cagagaaaat acaaacagca tcaaagcatc atttagaatt
    86101 actatcaaat gctatgaata gtgaagatag tgggactgat tttttagttg tgcactctga
    86161 agaccattat tcaaatgcat tatttgctca ttctttagta tctgaacttg tagatatatt
    86221 tgagatgatg gacccaagaa ttaataagaa ttaaatttct tgtaaatagt gcttgaagtt
    86281 tggctatagt ttattaaatc aatagattta ataaatgaac tcccttttac tttaaagtac
    86341 tagtatttat aaatttattt ataaatacag taaattttta aatagaaaag gagatattat
    86401 tatggaaaaa ttttcagtag taatagctgg aggaggaagt acatataccc cagaaatcat
    86461 attaatgttg ctagataact tagataggtt accattaaga gcaatcaaat tatatgataa
    86521 tgatgaagaa agacaaaata aggtagctaa agcttgtgaa atactaataa aggaaaagga
    86581 ccctaatata gagtatttag caacaacatg ccctaaagag gcttatacag atgtagattt
    86641 ttgtttagct catataagag ttggaaaact tgaaatgaga gaactagatg aaaagatacc
    86701 tctaaaacat ggagtagttg gtcaagaaac ttgtggacca ggtggaatag cttatggaat
    86761 gaggtctata gaaggtgttc ttgaaaacat agattatatg gaaaagtatt ctccaaattg
    86821 ttggatgtta aattattcta atccagcatc aataatagcg gaagctgtta gaaggttgag
    86881 acctaattct agggtaataa atatttgtga tatgccaata ggtatggaac ataatatagc
    86941 aaggattgca ggactcaaat ctcgtaaaca tatggatata agatactttg gattaaatca
    87001 ctttggttgg tatacttcaa ttaaagataa aaaaggaaat gaacttttac caaaattagt
    87061 agaacatata aaagaatatg gttttataaa tggtgaagaa ggaatgaaaa atgacaagaa
    87121 agatagttgg tttgaaacta atttatttac taaagaaata gtaaaaacag atttaactac
    87181 aataccaagt agttacttaa agtactatct atttccagat tatgttgtaa atcattctga
    87241 tgtaaattat actcgtgcca atgaagttat tgatggaaga gaaaaagaag tttttggttc
    87301 atgtgcattg atagaaaagc aaggacattc taagggcagt gggcttaaga taggaataca
    87361 tgcagagttt atagtggatt tagctacagc tctagctttt aatacacagg agcgtatgtt
    87421 attgatagtt caaaataatg gagctataga aaatatacaa gatgatgcta tggttgaaat
    87481 tccatgtata gttggaaaag acgggtatga accattatca atagggaaaa taccaacatt
    87541 ccaaaaaggt ttaatagaac aacaattagc agttgaaaaa ttagtagttg atgcttggat
    87601 tgagaagtct tataataaat tgtggcaagc acttatgcta tctaagacag ttcctagtgc
    87661 aacagttgca aaagaattac tagatgattt aatagaagca aataaaaatt attggccaaa
    87721 acttaattaa gaataatata tttttaaagt tcctacagtt tagtacatag cctagttaat
    87781 gtatttgtag ggactttatt tatttacaaa tgagatacaa gtggcaaaca tagtgtattt
    87841 tgcagttagg aaagtaggtt tagttacttg ttagttggat taaatttagg tacaataatt
    87901 tactatcaat caatagaaat aaccagagaa gttgcataat aaaaaattta cacttttaac
    87961 aggatttatg taggtgttta tagaaataaa taaatatgta cataaataca taattatttt
    88021 taagtctaaa atacaagaat ggagagatgg ctatgaagtg gagagattat gctgatgatg
    88081 taaatttatt tgaggatttt gataaaacta tcaagcctct aactgacgaa caaagaagaa
    88141 aaaatataaa cactttaatt gcatattttt caaaagaagt tccttctaaa atatacaatt
    88201 tatcaaatga tgaaattaag cctagagata tacttagagg acttttgaat gtatatccac
    88261 caaaagaaat tgctccagag atacttaata tgttacataa tttattgttg attgaatgtg
    88321 aagaaagaga gttagtagat gtaaatgata tagaagaagt agaggaaggg attgccatat
    88381 ggagaggtaa tataacgaat ttaagagcag atgcaatagt aaatgctgca aataacaagt
    88441 tattagggtg tttacaacca ttacatctat gcgtggataa tgagatacat tcatgcgcag
    88501 gtcctagact tagagaagat tgtgacaaaa taataaaaaa acaagggcat ttagaatata
    88561 ctggagatgc taagataact agaggctatt gtttacctgc aaaatttgta gtacatactg
    88621 ttggacctat tgtatctggt ggtcagccaa gtaaagagca agaaaagcaa ctgcttcatt
    88681 gttataaatc atgtttaaat acaataaaag aaattgatga aataaaaaat attgtttttt
    88741 gtggaatttc tacaggtgta tttggttatc caaaaaaaga ggcagctaat cttgctgtaa
    88801 gtagagttag actatggcta aaagaaaatc ctgaaaaaaa tttaaaagtt gtatttaatg
    88861 tgtttactga agaagaagaa gagaaatata gaagaatatt taaataatat tatgtaacag
    88921 aatcctaaaa atacttatta tataatacaa attcattgta taagataata atttacaagt
    88981 agtaaaaatt aataaaatat aatttgtatt tttaataaat aagtaggtat aatagaaatt
    89041 ataagaatag tataatcaat tatgctatta cttagaaaat ataatatagg aaaattgtat
    89101 ggtaaataaa tatgaaaaat agttttaaaa attgtattag tttaagaaat aaatttataa
    89161 ttatatcaat tgtgtttcta ttaatcctat taattgtatc ttatatattt ggcaaattag
    89221 tgtataatag ttcggttggt ttagagcagt taataaaaaa cgaagatata gtaaaaatat
    89281 tttctgagag aaaagataaa ccactggaga aattaaaaaa ctacaagaca tctgaattaa
    89341 tgatacaaag ttctaataat tacaagcttg aaagtctttt tataacttca aatataaaga
    89401 caagagatac tatgatactt gttcatggaa ttggaagtag ttactatgaa atgttaaagg
    89461 tagcatatag atatttagat aaaggttata atgtattagt ttataatcaa agaaatactg
    89521 gtaatagtgg tggagataat tacacatttg gtctttatga aaggtatgat ttagatagtc
    89581 tagttaaatt tgtaaaaaat aaatttcctg aaggaagatt aggagtgcat ggattttcca
    89641 tgggagcagg gacagctgct atgcattcag agataaattc aaaagatgat aaggtcgatt
    89701 tttatatact ggattctcct tattctgaaa tgaaagatgc aattagaatg ggagtactag
    89761 aaaaacgaat accagatata ttaatcaatt atgtggtgat ttgtggagat ttatataata
    89821 agtttaaatc tggattttgg tacagtgatg taaaaccata tgagtcagtt gagaaatcta
    89881 atgtacccat actgtttata catggaacaa aagatactgt ttgtaattat caaaatagca
    89941 agaaaatgta tgatttagtt aaacatgata aaaaagacct atggcttata gaaggtattg
    90001 gtcatgttga tggatttgaa catgatagta cagtatactt caataaaata tttaaattta
    90061 tagatagtaa tgttttaagt gataaaagtt aattgaatat tagtagctta tttatttttg
    90121 tatttattaa aaaatagata ggctattttt atgtttaaat ataagttttg tttagtaatg
    90181 tgaattaatt tctagtaaaa atgaaaataa ctaccaatta aattcattta tacctcaaat
    90241 aaaagagtta gtattagatt acaatcaaat ctaaagaaaa gagaggtagt atatatgaaa
    90301 aacaaaaata ataaagataa aaacatgttg aatattaaag tattgagagt tctaggagtg
    90361 ctattaatac tttttgatta tacgggtgat actttgaatt tttataattt cttcgcaaag
    90421 ccattagtat cgggtaattt atataagaca acaggtactg actgtattgt atttttatta
    90481 tttattgtag agtgtgtata cctagtggga agatatatat taaaagttaa gataaattgg
    90541 agtgagatta ttgaaaatga gaaaggtaat tttataaata acttgttggt tgaaaaaata
    90601 caagaagaaa gcaacattgt atataattta ttaaactcat atgtgttgcc acatatatat
    90661 aagaaagcaa gggtgttgat gtttaaaaca tatcatatgt taatctacat taaagaaaaa
    90721 tactattatg taaatatata ttaatataat atgattgcac aattaattat attatatttt
    90781 gtattggatg ataaaatgaa agacataaat tttttgagac actaaaatcg caatttattt
    90841 cgtgtttaag ttataaattt tgtgaaaaat tataaatctt ataaaataga ttgcgatttt
    90901 aatcttaaac ttttgctata gtttttccag tatcagttaa atcatatccg ccaagacctt
    90961 gaagttcagc tttaaactca ggagagttta ttatgttaat tatagtttgg taaactggat
    91021 tttgtaagtc ttctttttta ataactaaat catagcgctc tttgtgaaga ggaataaagt
    91081 cgatattatt tacttgtaaa gcagcttttt catttcccaa accaacatca gctattccac
    91141 gagaaacagt acttgcaact ccaagatgtg ataattcttc attatcataa ccttttatat
    91201 gtttaccatt aaagtttaga agtctaagtt taccatctag taaaacccta gttccagaac
    91261 ctttttccct atttacaatg gttatacttg gttttgttaa atcctcccag gttgttatct
    91321 ctttaggatt tcctttagca acatagaaac cttgcattct ataagctaga tttataagta
    91381 cacatggtat tcctggcaat agctttttaa caaaagtgct attatattca tccgtttcga
    91441 aatcccatag atgggatgat gctatagaaa ctctgccatt atataactca tacaaagcat
    91501 tataactacc tatataagag cgaaatgtac ttattccatc caattttttt tcaacagacc
    91561 tagctaaaat gtctaatatt acatcttgac cagaaataat aattttgaaa ttattattta
    91621 tatctatatt tttattgttg aaatgtgtat cctttacttt accagttttt tggctgttga
    91681 tatattcttc aacatcttta gtatcaactc ttattttttt ccctacttta taagaaggaa
    91741 gttcacctct tttgattaat tcatatacag tattttttgt tatctttaat aattcagcta
    91801 cctcgacagg tgtcaaagat gataatgagt ccataatcca cctccatata aggttatttt
    91861 aacattaaaa aaaggaaaat gtagcaaaat atttaaaagt agtgtaaata aattacttga
    91921 aaatttatta tcatgtatat ataattaaac tatatataac aaaacatgat aaaacataat
    91981 aaaacatatt aaaatgtgta tcaaatttac aaaaagggag attgttatga aaaaaatatt
    92041 gggaatatta ggattagttg catgtttaac tttggggaca gttgggtgca atagtaatga
    92101 agacaaaaca gatgatggaa aacaagaaaa aacaactaaa agtagtgatt cagtagagtt
    92161 aaatatatcg gctgctgcaa gtttaaaaga agcaatggca aagattgaag aagaatataa
    92221 aaaagttgat tcaaatgtaa aacttacagt taactatgga gcatcaggct cattacaaca
    92281 acaaatagaa caaggagcac cttgtgattt atttatttca gcaggtcaaa aacaaatgaa
    92341 agctttggat gaagagaagt tattagtttc tgatactatg aaagatttag taaaaaatga
    92401 tttagttctt atttcttctg ctgacagtag tgtatcaggt atgaaagatt tgactacaga
    92461 taaagtgaag aaaattgctg ttggtgaagt tgaaagtgtt ccagctggta agtatgcaga
    92521 tgaggtgtta actaatttaa atttaaaaga taagttaaaa gataagctag tatttgcaaa
    92581 agatgtaaaa gaagttttag catgggtgca atcaggaaat gctgatgttg gattcgttta
    92641 cttcagtgat actgtcaata atgataagat aaaagtagtt gaaaaaacag acgaaaaaac
    92701 tcattcacct attacatatc cagtttcagt aattaaagct agtaaaaacg tagatgctgc
    92761 taagaaattt gaagaatttt tattaagtga gtcaggacaa aagatttttg aagaatttgg
    92821 atataaaaaa gtagaataaa cttataaata aattatgtgt aattaagtat aaattatata
    92881 taaataaatg aaaattgaaa ataattgtgt attataataa aatggaaata gtgaaattaa
    92941 tagagttatt agtttcacta tttccattta aaattaagga gggaaagatg ggaacagatt
    93001 ggtcaccctt atggatatca cttaagacat ctattttgtc aacaataata acttttgtaa
    93061 taggaatatt tgtgtcatat attatggcta actatagagg taagtggaag ggtcttatag
    93121 atggactatt tacacttcca ctaattttgc caccaacagt tgtaggtttc tttttattat
    93181 tactatgtgg gaagaatgga tttataggaa agtttttatt aaatttcgat aggactttaa
    93241 tatttagttg gacagcaact gtaatttcag cagtagtggt gtcttttcct atgatgtata
    93301 gaacttcaag gtcagctttt gaacagattg ataataatat gctgtcagct gctagaacat
    93361 taggtcttaa tgaatggaaa gtatttttta agattgcagt tccattagca tggcctggaa
    93421 taattggtgg attggtgctg tcgtttgcca gagctcttgg cgaatttggt gctacactta
    93481 tgatagctgg aaatatacct ggaaaaactc aaactatgcc aatagctata ttttttgctg
    93541 ttgaaggcgg agatatgaat aaagctatga tgtgggttat gattattgta gcaatatcta
    93601 tagcaatgat tttattacta aattattggt cggaatttca gcaaaaaatt ataggaaaga
    93661 ggtgtggata gttgagctta tacgtggata ttgaaaaaga tttatcctct tttaaactaa
    93721 aggtagaaat taaacaagaa aaaggtactc tggggttttt gggggaatct ggttctggaa
    93781 aaagtatgac attaaaatgt atagcagggc ttgagaaacc aacaagaggt aaaattgtat
    93841 taaatgatag agttctattt gattctgaaa agaagataaa tttatcaaca caagatagaa
    93901 aggtaggatt tttatttcaa aactatgctt tgtttccaca tatgactgta agtcaaaata
    93961 tagaacttgg gcttttaaaa ctaagtaaga gtgaaaaaaa ggaaatagta gcaaggtact
    94021 tagatatact taaattaaat gggtttgaag ggagatatcc ttggcaatta tctggtggtc
    94081 aacaacaaag ggtagcacta gctagagcat tggcaacatc tccagatata ttacttttag
    94141 atgaaccttt ctcagcactg gaccatcatt taagaagtaa tatggaaaaa gaacttatga
    94201 atatgttaaa agattacaag ggagatatac tatttgttac tcatgatatt gaagaagctt
    94261 accgagtttg tgatgatatt atagtgtaca acaaaggaga aggtcttcca aagagaccta
    94321 aaaaagagct ctttgaatct ccaaagtacc ttatagaagc taagataaca gggtgtaaaa
    94381 atatatccaa attaaataga ctggataaaa atactattta tgctacagac tggggatgcg
    94441 agttgacatt aaatagagaa ataggtgata atatagaata tgtgggaatc agggagcatc
    94501 atattaaggt cttggattct aatgaagatt taaatgaaaa gttatgtttc gaattgatta
    94561 acattgtaga aaatcctttt acatatacta tatatgttag aaaaactgat ttatctaacg
    94621 aatgtgtacc tattcaaata gaattggaaa aaagtaaaat gagatttaag aaaggtgaca
    94681 gaatatattt agattttcca caggaatatt tattttgctt tagatacaat tataacaaaa
    94741 aggagtaaac tatatgactg aaaaagaaaa aatgttgtct ggaaaaggat actatgcaaa
    94801 tgatgaattg ttagtaaaag aaagagagta ttgtaaaaaa ttaactagat tgtttaataa
    94861 tactttagag gatgaatatg aaaaaagaga agatatttta agacaactat ttggttcagt
    94921 tggcaagcaa ataaatgtag aacaaaacat taggtgtgat tatggatata acatacatgt
    94981 aggcgaaaat ttctttgcaa attatgattg tattttttta gatgtatgta aaattgaaat
    95041 aggtgacaat gtaatgttag ctccaaacgt tcaaatctat acagcctatc atccaattga
    95101 tgcacaactt agaaattcag gcatagagta tggttctcct gtaaaaatag gtgataatgt
    95161 atggataggt gggggagtaa tcataacacc aggaattact ataggtgata atgtagtaat
    95221 aggtgcagga agtgtagtca caaaagatat accaccaaat actgtagctg ttggaaatcc
    95281 atgtagagta ataaagaaaa tagaagaata aatatgattg tataaagttt atacaagtaa
    95341 aatttataca atcatattaa gagcatttac atataatctt taaatagata atacattaaa
    95401 ataaaaatat atgcctgttt ctataaatta atttatagaa acaggcatat taatcgtata
    95461 tagaaaatat ctttctattc ttgtttagtc tttacataag aaatattttc attagaaggt
    95521 ttttccatac ctaaagcttt taatatatct tcattaacaa tgatatctgt atcatctgat
    95581 gtagccacag gcatatcaga tactgattcg ccatttaaaa ttttaactgc catttcacct
    95641 gttttgtaac ctagtttttc gtagttgata ccttgacaag caagagcacc tttttcaact
    95701 ggcccagatt cagctgctat aacaggtatt ttattctcag tagctatttt agagactata
    95761 ggcatagaag aagccactaa gttatctgta ggaacatata atacgtctat tttgccaact
    95821 aaactagaaa taccttggtt aacttcattt gaagtagtta tacctttttc aacaacttta
    95881 aatccatttt tagatgcata ttcttttaaa gcatcaactt gaactttgga atttacttca
    95941 ctagtattgt acataactcc tatagttttt gccttaggag caaatatttt aagaagttct
    96001 aaacctttgt ctacagaaac aaaatctgat gttccagata catttgtgcc tggcttttca
    96061 agagttttaa ctaatccagc agcaacaggg tcactcacag cagtaataag tataggtata
    96121 tctttagtag cattaaatgc tgcctgagct gatggagtag atatagcaaa tattaagtcc
    96181 ttcttatcag atgcaaattt actcgcaata ctttgtgtag taggcatgtc attttgagca
    96241 ttttggaagt ctatatcaat attttctcca tctttaaatc cgttcttttc taatgctttt
    96301 acaaaaccta tcctagtggc atctaatgct ggatgttcaa ccagttgagt tataccaatt
    96361 tttttaactt ctttaccttt agaattactt tcttgttttg aattaccaga gtctcctcct
    96421 tgtgaacacc ctgtaagcat agatatacta agagcaccag ctaaaatcaa acttgccaat
    96481 ctttttttat taatcatttt tatatccccc tcaaaaattt attattatat atgttcatat
    96541 attcatatga attattacaa agtaaccata attattgtaa ttttaacttt attttaaagc
    96601 cgagtttaat acaatagata tattatttta aactgcatat tcaaattttt ctaagatttc
    96661 ttcaactgtt aattgttctt tttctttacc ttttacatct aatacaactt cacccttatg
    96721 aagcattatc aatctatcac cataatgaag agcgtgtttt aagttgtgag taaccataag
    96781 tgtagttata tttttttccc ttacaatctt attagtcaat tcaattactt catttgatgt
    96841 ttttgggtca agtgctgctg tatgttcatc aagtaataaa actgatggac ttgttaagca
    96901 cgacataatt agtgataatg attgtctttg acctcctgat aaaaatttta cttgaacatc
    96961 aaggtatttt tttaaatcaa gagatacacc ttccaataaa ttttctaaga aatctctttt
    97021 gtaacgaaga cattttctta gatttaatag ttttcctttg ttaagagcta aagacaagtt
    97081 ttctctaaca gtcatagaag ggcaagttcc aagacttggg tcttgaaaaa ctctacttac
    97141 tatttgagtt cttctgtgtt cagctaaatt agacaagtta tgtttattta ataatacttg
    97201 accagaagat tcttttataa gccc
//
LOCUS       DAEQJM010000008        96635 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.008, whole genome shotgun sequence.
ACCESSION   DAEQJM010000008 DAEQJM010000000
VERSION     DAEQJM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 96635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96635
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.008"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            109..300
                     /locus_tag="KRQ43_000704"
     CDS             109..300
                     /locus_tag="KRQ43_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBH2741076.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            455..1864
                     /locus_tag="KRQ43_000705"
     CDS             455..1864
                     /locus_tag="KRQ43_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH2741077.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIRIFKDKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKICGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            1995..2684
                     /locus_tag="KRQ43_000706"
     CDS             1995..2684
                     /locus_tag="KRQ43_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBH2741078.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2687..3622
                     /locus_tag="KRQ43_000707"
     CDS             2687..3622
                     /locus_tag="KRQ43_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBH2741079.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3619..4512
                     /locus_tag="KRQ43_000708"
     CDS             3619..4512
                     /locus_tag="KRQ43_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBH2741080.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4590..5336
                     /locus_tag="KRQ43_000709"
     CDS             4590..5336
                     /locus_tag="KRQ43_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBH2741081.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRASSRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5337..6170
                     /gene="rsmI"
                     /locus_tag="KRQ43_000710"
     CDS             5337..6170
                     /gene="rsmI"
                     /locus_tag="KRQ43_000710"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBH2741082.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6193..6897
                     /locus_tag="KRQ43_000711"
     CDS             6193..6897
                     /locus_tag="KRQ43_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBH2741083.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7085..7513)
                     /locus_tag="KRQ43_000712"
     CDS             complement(7085..7513)
                     /locus_tag="KRQ43_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH2741084.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7550..8980)
                     /locus_tag="KRQ43_000713"
     CDS             complement(7550..8980)
                     /locus_tag="KRQ43_000713"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBH2741085.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9112..9696
                     /locus_tag="KRQ43_000714"
     CDS             9112..9696
                     /locus_tag="KRQ43_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HBH2741086.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9712..10233
                     /locus_tag="KRQ43_000715"
     CDS             9712..10233
                     /locus_tag="KRQ43_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HBH2741087.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10299..10545
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10629..12566
                     /gene="metG"
                     /locus_tag="KRQ43_000716"
     CDS             10629..12566
                     /gene="metG"
                     /locus_tag="KRQ43_000716"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBH2741088.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12596..13366
                     /locus_tag="KRQ43_000717"
     CDS             12596..13366
                     /locus_tag="KRQ43_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBH2741089.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGICYEEVCRVTKENAKKFFNIK"
     gene            13703..14134
                     /gene="phnG"
                     /locus_tag="KRQ43_000718"
     CDS             13703..14134
                     /gene="phnG"
                     /locus_tag="KRQ43_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBH2741090.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14149..14724
                     /gene="phnH"
                     /locus_tag="KRQ43_000719"
     CDS             14149..14724
                     /gene="phnH"
                     /locus_tag="KRQ43_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBH2741091.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTVSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSTINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14727..15812
                     /locus_tag="KRQ43_000720"
     CDS             14727..15812
                     /locus_tag="KRQ43_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HBH2741092.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRDFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15832..16701
                     /locus_tag="KRQ43_000721"
     CDS             15832..16701
                     /locus_tag="KRQ43_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBH2741093.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16694..17560
                     /locus_tag="KRQ43_000722"
     CDS             16694..17560
                     /locus_tag="KRQ43_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741094.1"
                     /translation="MSKINVSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17601..18314
                     /locus_tag="KRQ43_000723"
     CDS             17601..18314
                     /locus_tag="KRQ43_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2741095.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMAKGTISESGVA"
     gene            18315..19484
                     /locus_tag="KRQ43_000724"
     CDS             18315..19484
                     /locus_tag="KRQ43_000724"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBH2741096.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDRIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVLNTIVNGKTVYKREV"
     gene            19488..20324
                     /locus_tag="KRQ43_000725"
     CDS             19488..20324
                     /locus_tag="KRQ43_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH2741097.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20325..21320
                     /locus_tag="KRQ43_000726"
     CDS             20325..21320
                     /locus_tag="KRQ43_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2741098.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLDVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21338..23026
                     /locus_tag="KRQ43_000727"
     CDS             21338..23026
                     /locus_tag="KRQ43_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH2741099.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYIIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYIPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23038..24105
                     /locus_tag="KRQ43_000728"
     CDS             23038..24105
                     /locus_tag="KRQ43_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH2741100.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24591..24707
                     /locus_tag="KRQ43_000729"
     CDS             24591..24707
                     /locus_tag="KRQ43_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein"
                     /protein_id="HBH2741101.1"
                     /translation="MDDDINMIAIRPEDIRVEFNRDFKEIIDLKLRPYRYKN"
     gene            24871..25938
                     /locus_tag="KRQ43_000730"
     CDS             24871..25938
                     /locus_tag="KRQ43_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH2741102.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PNSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26130..26660
                     /gene="rnmV"
                     /locus_tag="KRQ43_000731"
     CDS             26130..26660
                     /gene="rnmV"
                     /locus_tag="KRQ43_000731"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBH2741103.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMQRIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26831..27700
                     /gene="rsmA"
                     /locus_tag="KRQ43_000732"
     CDS             26831..27700
                     /gene="rsmA"
                     /locus_tag="KRQ43_000732"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBH2741104.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27766..29037
                     /locus_tag="KRQ43_000733"
     CDS             27766..29037
                     /locus_tag="KRQ43_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741105.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDSDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEEYEELEEDEEIEDNEESDRDEDS
                     EEEYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSGDEEIEEFNNYKEIENYNRV
                     KVQEEYIDIEYDEEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGV
                     SQGESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMP
                     YLGYLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGST
                     GFLRYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29188..30303
                     /locus_tag="KRQ43_000734"
     CDS             29188..30303
                     /locus_tag="KRQ43_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH2741106.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30489..31385
                     /locus_tag="KRQ43_000735"
     CDS             30489..31385
                     /locus_tag="KRQ43_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH2741107.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASIVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31455..32252
                     /locus_tag="KRQ43_000736"
     CDS             31455..32252
                     /locus_tag="KRQ43_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741108.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32308..33660)
                     /locus_tag="KRQ43_000737"
     CDS             complement(32308..33660)
                     /locus_tag="KRQ43_000737"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBH2741109.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            33879..34757
                     /gene="purR"
                     /locus_tag="KRQ43_000738"
     CDS             33879..34757
                     /gene="purR"
                     /locus_tag="KRQ43_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBH2741110.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            34913..35191
                     /gene="spoVG"
                     /locus_tag="KRQ43_000739"
     CDS             34913..35191
                     /gene="spoVG"
                     /locus_tag="KRQ43_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HBH2741111.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35401..36780
                     /gene="glmU"
                     /locus_tag="KRQ43_000740"
     CDS             35401..36780
                     /gene="glmU"
                     /locus_tag="KRQ43_000740"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBH2741112.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEAEVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSNVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SVVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            36875..37825
                     /locus_tag="KRQ43_000741"
     CDS             36875..37825
                     /locus_tag="KRQ43_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HBH2741113.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38665..38750
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            38912..39433
                     /locus_tag="KRQ43_000742"
     CDS             38912..39433
                     /locus_tag="KRQ43_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH2741114.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTNDEGVTLTEAQSAKLLSDIGENKIYTSVTADNLGNPLTSNTKVDNKVLY
                     IVLIDNTVMDSTK"
     gene            39584..41260
                     /locus_tag="KRQ43_000743"
     CDS             39584..41260
                     /locus_tag="KRQ43_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH2741115.1"
                     /translation="MAKKVRIGDKLVEKGYITEDQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41272..42480
                     /locus_tag="KRQ43_000744"
     CDS             41272..42480
                     /locus_tag="KRQ43_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH2741116.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            42495..44207
                     /locus_tag="KRQ43_000745"
     CDS             42495..44207
                     /locus_tag="KRQ43_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBH2741117.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETHDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            44200..45108
                     /gene="pilO"
                     /locus_tag="KRQ43_000746"
     CDS             44200..45108
                     /gene="pilO"
                     /locus_tag="KRQ43_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HBH2741118.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45135..45701
                     /locus_tag="KRQ43_000747"
     CDS             45135..45701
                     /locus_tag="KRQ43_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH2741119.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            45738..46265
                     /locus_tag="KRQ43_000748"
     CDS             45738..46265
                     /locus_tag="KRQ43_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH2741120.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            46286..47824
                     /locus_tag="KRQ43_000749"
     CDS             46286..47824
                     /locus_tag="KRQ43_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741121.1"
                     /translation="MRKWNKFKSERGAALVLVLIVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEKNIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            47924..49006
                     /locus_tag="KRQ43_000750"
     CDS             47924..49006
                     /locus_tag="KRQ43_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBH2741122.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESIFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            48987..49769
                     /locus_tag="KRQ43_000751"
     CDS             48987..49769
                     /locus_tag="KRQ43_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH2741123.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGILFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILIFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            49871..50521
                     /locus_tag="KRQ43_000752"
     CDS             49871..50521
                     /locus_tag="KRQ43_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH2741124.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     AQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50535..51095
                     /locus_tag="KRQ43_000753"
     CDS             50535..51095
                     /locus_tag="KRQ43_000753"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBH2741125.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            51112..54498
                     /gene="mfd"
                     /locus_tag="KRQ43_000754"
     CDS             51112..54498
                     /gene="mfd"
                     /locus_tag="KRQ43_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBH2741126.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGAENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54529..55524
                     /locus_tag="KRQ43_000755"
     CDS             54529..55524
                     /locus_tag="KRQ43_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH2741127.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            55648..56187
                     /gene="spoVT"
                     /locus_tag="KRQ43_000756"
     CDS             55648..56187
                     /gene="spoVT"
                     /locus_tag="KRQ43_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HBH2741128.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56307..57920
                     /locus_tag="KRQ43_000757"
     CDS             56307..57920
                     /locus_tag="KRQ43_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH2741129.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            58027..59475
                     /gene="mazG"
                     /locus_tag="KRQ43_000758"
     CDS             58027..59475
                     /gene="mazG"
                     /locus_tag="KRQ43_000758"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBH2741130.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59564..59842
                     /locus_tag="KRQ43_000759"
     CDS             59564..59842
                     /locus_tag="KRQ43_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBH2741131.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            59914..60156
                     /locus_tag="KRQ43_000760"
     CDS             59914..60156
                     /locus_tag="KRQ43_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBH2741132.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60218..60472
                     /locus_tag="KRQ43_000761"
     CDS             60218..60472
                     /locus_tag="KRQ43_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HBH2741133.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60473..61006
                     /locus_tag="KRQ43_000762"
     CDS             60473..61006
                     /locus_tag="KRQ43_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741134.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            61012..61296
                     /locus_tag="KRQ43_000763"
     CDS             61012..61296
                     /locus_tag="KRQ43_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBH2741135.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61409..62329
                     /locus_tag="KRQ43_000764"
     CDS             61409..62329
                     /locus_tag="KRQ43_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HBH2741136.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62419..64791
                     /gene="spoIIE"
                     /locus_tag="KRQ43_000765"
     CDS             62419..64791
                     /gene="spoIIE"
                     /locus_tag="KRQ43_000765"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HBH2741137.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNNEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65142..67034
                     /gene="pepF"
                     /locus_tag="KRQ43_000766"
     CDS             65142..67034
                     /gene="pepF"
                     /locus_tag="KRQ43_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH2741138.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAIAVMNNN
                     DTEDDAEKKQEVDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMSDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESVDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67148..68113
                     /gene="galU"
                     /locus_tag="KRQ43_000767"
     CDS             67148..68113
                     /gene="galU"
                     /locus_tag="KRQ43_000767"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH2741139.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            68613..70217
                     /gene="rho"
                     /locus_tag="KRQ43_000768"
     CDS             68613..70217
                     /gene="rho"
                     /locus_tag="KRQ43_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBH2741140.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQENRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70370..70570
                     /gene="rpmE"
                     /locus_tag="KRQ43_000769"
     CDS             70370..70570
                     /gene="rpmE"
                     /locus_tag="KRQ43_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBH2741141.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            70715..71608
                     /locus_tag="KRQ43_000770"
     CDS             70715..71608
                     /locus_tag="KRQ43_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HBH2741142.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            71626..72474
                     /gene="prmC"
                     /locus_tag="KRQ43_000771"
     CDS             71626..72474
                     /gene="prmC"
                     /locus_tag="KRQ43_000771"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBH2741143.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72518..73582
                     /gene="prfA"
                     /locus_tag="KRQ43_000772"
     CDS             72518..73582
                     /gene="prfA"
                     /locus_tag="KRQ43_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBH2741144.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            73711..74391
                     /locus_tag="KRQ43_000773"
     CDS             73711..74391
                     /locus_tag="KRQ43_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBH2741145.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74420..75460
                     /locus_tag="KRQ43_000774"
     CDS             74420..75460
                     /locus_tag="KRQ43_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBH2741146.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75477..75926
                     /locus_tag="KRQ43_000775"
     CDS             75477..75926
                     /locus_tag="KRQ43_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HBH2741147.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            75943..76395
                     /gene="rpiB"
                     /locus_tag="KRQ43_000776"
     CDS             75943..76395
                     /gene="rpiB"
                     /locus_tag="KRQ43_000776"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH2741148.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76431..77060
                     /gene="upp"
                     /locus_tag="KRQ43_000777"
     CDS             76431..77060
                     /gene="upp"
                     /locus_tag="KRQ43_000777"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBH2741149.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            77360..78175
                     /locus_tag="KRQ43_000778"
     CDS             77360..78175
                     /locus_tag="KRQ43_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBH2741150.1"
                     /translation="MKNCIAVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78401..78838
                     /locus_tag="KRQ43_000779"
     CDS             78401..78838
                     /locus_tag="KRQ43_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBH2741151.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            79023..79250
                     /locus_tag="KRQ43_000780"
     CDS             79023..79250
                     /locus_tag="KRQ43_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HBH2741152.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79255..79641
                     /locus_tag="KRQ43_000781"
     CDS             79255..79641
                     /locus_tag="KRQ43_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HBH2741153.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAIRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            79644..80348
                     /gene="atpB"
                     /locus_tag="KRQ43_000782"
     CDS             79644..80348
                     /gene="atpB"
                     /locus_tag="KRQ43_000782"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBH2741154.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80417..80677
                     /gene="atpE"
                     /locus_tag="KRQ43_000783"
     CDS             80417..80677
                     /gene="atpE"
                     /locus_tag="KRQ43_000783"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBH2741155.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            80800..81297
                     /gene="atpF"
                     /locus_tag="KRQ43_000784"
     CDS             80800..81297
                     /gene="atpF"
                     /locus_tag="KRQ43_000784"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBH2741156.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81294..81839
                     /locus_tag="KRQ43_000785"
     CDS             81294..81839
                     /locus_tag="KRQ43_000785"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBH2741157.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            81856..83358
                     /locus_tag="KRQ43_000786"
     CDS             81856..83358
                     /locus_tag="KRQ43_000786"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBH2741158.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83386..84264
                     /gene="atpG"
                     /locus_tag="KRQ43_000787"
     CDS             83386..84264
                     /gene="atpG"
                     /locus_tag="KRQ43_000787"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HBH2741159.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84277..85671
                     /gene="atpD"
                     /locus_tag="KRQ43_000788"
     CDS             84277..85671
                     /gene="atpD"
                     /locus_tag="KRQ43_000788"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBH2741160.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            85674..85934
                     /gene="atpC"
                     /locus_tag="KRQ43_000789"
     CDS             85674..85934
                     /gene="atpC"
                     /locus_tag="KRQ43_000789"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HBH2741161.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            86396..86776
                     /locus_tag="KRQ43_000790"
     CDS             86396..86776
                     /locus_tag="KRQ43_000790"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBH2741162.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRLFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            86791..87252
                     /locus_tag="KRQ43_000791"
     CDS             86791..87252
                     /locus_tag="KRQ43_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH2741163.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            87273..87863
                     /locus_tag="KRQ43_000792"
     CDS             87273..87863
                     /locus_tag="KRQ43_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741164.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            87878..89035
                     /gene="alr"
                     /locus_tag="KRQ43_000793"
     CDS             87878..89035
                     /gene="alr"
                     /locus_tag="KRQ43_000793"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH2741165.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            89068..89355
                     /locus_tag="KRQ43_000794"
     CDS             89068..89355
                     /locus_tag="KRQ43_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBH2741166.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            89324..89707
                     /locus_tag="KRQ43_000795"
     CDS             89324..89707
                     /locus_tag="KRQ43_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBH2741167.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            89878..90705
                     /locus_tag="KRQ43_000796"
     CDS             89878..90705
                     /locus_tag="KRQ43_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH2741168.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            90698..91639
                     /locus_tag="KRQ43_000797"
     CDS             90698..91639
                     /locus_tag="KRQ43_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH2741169.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGINAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            92062..93156
                     /locus_tag="KRQ43_000798"
     CDS             92062..93156
                     /locus_tag="KRQ43_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741170.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            93382..93798
                     /locus_tag="KRQ43_000799"
     CDS             93382..93798
                     /locus_tag="KRQ43_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741171.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(93980..94549)
                     /locus_tag="KRQ43_000800"
     CDS             complement(93980..94549)
                     /locus_tag="KRQ43_000800"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBH2741172.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNN"
     gene            94703..95860
                     /locus_tag="KRQ43_000801"
     CDS             94703..95860
                     /locus_tag="KRQ43_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HBH2741173.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            96047..>96635
                     /locus_tag="KRQ43_000802"
     CDS             96047..>96635
                     /locus_tag="KRQ43_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH2741174.1"
                     /translation="MFNKNEILKKLIEEYDVKTTTDIQDMLKDLFASTIHQMLEAELD
                     DHLGYDRYDNKNKNTKNSRNRYRNKNVKSDFGEITLNIPRDRNGDFEPKVIRNYENDI
                     SGIENQVIGMYSKGMSTRDISSHLKSIYGIDISHSLIAKITDRVLPLAHEWQSRALDM
                     VYPIVFMGAIHYKVRSEGRIINKAAYIAIGVNLEGI"
BASE COUNT        38815 a        10392 c        17782 g        29646 t
ORIGIN      
        1 ttttttgtca aaaaaaacaa aaaatacgta tttatttttt catttcggga aaactaaaca
       61 caggaattat ggactttata aaaatttaat tcttgaggag tgatataagt gaaaaaagtt
      121 gctttaattt tagctataat aggtgcgctt aactggggtg caattggtat tctaggtaca
      181 gacttaatag gtagtatctt tggtggaaca tatgaaatgg taagtagaat aatatacttc
      241 attgtaggtt tagctggatt atacttaata ccaagtttaa tgtctgatga tagagaataa
      301 tttatgcttt tatgttaaat acctcattct aaatgtttag aatgaggtat ttaattttat
      361 aaaaatatta atttgtttct tttttaatgg taaaatagat aagaattgaa gttttaaaaa
      421 gaagtattat gtaaaaaagg agtactatta atatatgttt attattaatg aattaaataa
      481 gattgtaaat gaagaagtaa tatcttttca tatgcctggt cataaaaagg gacaggttta
      541 taaaaagtta ggatataaag atatactaaa aaatttgtat aaaatggata caactgagat
      601 attaggaaca gataatttac actttccgga aggaattata aaaaattcac aaaaaaaagc
      661 atcaagagta tttaaaagtg attatacttg ctatttagta aatggtagta gctgtggaat
      721 acaatctgca ataatgtcag tatgtagtcc taaaagtaaa ataataacaa atagagactg
      781 tcatcagtct gttataaatg gatgtatttt aggagatata gatatagagt atgtgccttg
      841 tgagataagt gaagagacaa atgtcttaaa agggatatct ataagtaatg tgattgatat
      901 aatagataaa aacttggatg caaaagcagt actgcttact tatcctacat attatggaat
      961 gacatatgat ttagaataca tatgtaatta tgcacatagc aaaaagatgg tagtgatagt
     1021 agatgaagca catggtgcgc atttagggct tagtgagagg cttcctaaaa cagctcttga
     1081 gcaaggtgca gatatagttg tacagagtac acataaaact cttccagcat ttacacaatc
     1141 gtcaatgata catatacagg gagaccgagt tgatatagat aaaatattga acatgttaag
     1201 aattacagaa tcttcaagcc cttcatattt attattatct tctctggaat tagcagtaga
     1261 tatatatgaa aataaaggaa aagaattaat ggaagagctt ttaaataata ttagaatttt
     1321 caaagataaa gttgattcaa atattaatat atatgacaca aatgataaaa caaaaatatt
     1381 tatatcatct aaaaacatgg gtttaacagg ttatgaacta gaaaatattt tgagaaacaa
     1441 atataacata caagtggagt tatctaatta ttatggagtt cttttaatat gtacaatagg
     1501 aaatactgct gaggatttct ctagtttaga aacagcatta aacaatgttg taaaggaaga
     1561 ctttaaattt gaaaagttag aaaataaaaa ataccctgtt gttattccaa agaaaatatt
     1621 aacacctaga gaagcatttt ataaaactaa aaaaagtgtt aaaatatatg acagcatagg
     1681 taaaatttgt ggtgaatgta tagttccata cccacctgga ataagtgtaa tatctcctgg
     1741 tgaagtaata agtaaagaaa taatagacta tctaatgttt tgtcattcta aaggcatgat
     1801 tgtgagtgga ttgaaagatg tagatttaaa ttttatacaa gtaatagatt tagaagacat
     1861 ttaaaaatta tgatataaaa gtagatagaa gtagatagtt taaaattgtg aagagaaata
     1921 aatagactgc ttatatagag ctatctaata aaagtactaa aaaagtaaaa agtgtttgta
     1981 tggaggatat gaaaatgaaa ggtaagttaa taattataga gagtggttca gatgcaagtg
     2041 gaaaggctac tcagacagaa atattatatg aaagattaaa aaaagaaggc tatatgatta
     2101 aaaaggtaga atatccaaat tatgaatctc catcatctgc cttagtgaaa atgtacctaa
     2161 aaggagactt tggtaaaaat gcatcagatg tagacccata tatagcatca acttttttta
     2221 cagctgatag gtatgcatca tttaaaaccg attgggagga gttttacaat gaaggtggaa
     2281 taattatcgc agatagatat acaacctcta atatggtaca tcaggcctct aaaatggata
     2341 tttgtgatag agaagagtat ttaaattggt tagctgatta tgaatttaat ttatttaaga
     2401 taccacaacc tgattgtgtt atatttttag atgtgcctat tgaatttagt aaaaagctta
     2461 tggagaatag aaaaaataaa attacagggg aagaaaaaaa ggatattcat gaaagtgaca
     2521 tagagtattt agagaaatct tacaacaatg ctttatatat agcagataaa tatgattgga
     2581 aaaaaataaa ttgtgtttta gataacaaat taagaagtat tgaaagtata cataatgaaa
     2641 tttataaaat agttcttgat tcaataaaac ctatggagag ataaatatgt attttgaaaa
     2701 tattataggg caagattttg caaagaaata tttaacaaat tctataaaga aaaataaact
     2761 taataatgcg tatatgtttg aaggaatgga tggaatagga aaaaagaaat ttgcagatga
     2821 attatcaaaa ctattacttg attatgaaaa tctcgaaaat agtccagact atgtactcat
     2881 aaaaccagat ggaaatagta taaaaatagc tcaaatcaga aatttacaat cagatatagt
     2941 aataagacct cataaagact ataaaatata tataatcaat aatgctgaaa aaatgactgt
     3001 ggaagctcaa aatgcacttt taaagacgct agaggaacct ccaaactatg ctataataat
     3061 cttagtcaca aacaacaagg aatctttatt agaaactata aaatctagat gtgatataat
     3121 aaagttctca cctataccaa ttgaagactt aaaacgttat ttgataaata caggtataga
     3181 agaagaaaga gctcaattat tggctatttt ttcgagagga agtattgaga atgctctaaa
     3241 tctatctcag tcttctgagt tttcaatgat gagagaagat atacaacagt atattcagat
     3301 aatgttagat aaaaacatag tggagatttt aaatatacca aacaatatgg aaaaatatag
     3361 aggtaagatt atagctttat tagatatgat gataaactat tttcgagata tcatcctatt
     3421 aaaagaaaat gtaaacaaga acatgttaat aaatgtagat aagctagttt tcattcaaaa
     3481 tatgagtgga aaaattagtt attctcaatt gtccaagatt attgatataa tagaagatgc
     3541 aaagagtaaa ataaaaagca attgcaattt caatataagc atacaagtta tgtctttaaa
     3601 tatatacgag gtgattaaat gataaagata gtaggtataa ggtttaaaag tgctgggaaa
     3661 atatattatt ttgaccctgt tgattttaat atagagcaag atatggatgt agttgtagaa
     3721 actgcaagag gcttggagta tgggaaagta gtcgttggtc caaaagatat ggatgaaagc
     3781 gaattagttt ctcctttgaa gccaattata agaatagcta cagaagaaga taaaaaagta
     3841 tatctagaaa ataaggaaaa ggcaaaagaa acttttgagt tgtgccaaca aaaaataaaa
     3901 gaacatgagt taacaatgtt tttaatagat tgtgagtata cgtttgatag gaataagttg
     3961 attttttact ttacagcaga aggaagaata gattttagag aattggtaaa agacttagct
     4021 gctatattta aaactagaat agaacttaga caaataggtg tcagagatga agctaaatct
     4081 ataggaggtc tagggccttg tggtagaaaa ctttgttgtt catcttggtt aggtgatttt
     4141 caaccagttt caataaaaat ggcaaaagac caaagtctat ctctaaatcc aacaaaaata
     4201 tctggaatat gtgggagatt attctgttgc ttaaaatatg agcatgatgt atatagtgaa
     4261 gcaatagaaa aaatgcctgt tgtaggtgca ttggtgcaat cagatgatgg aaaaggaaaa
     4321 gttgtagaag tgaatccttt attagaacaa attaaagtgg aatttcaaga caagacagta
     4381 aagatataca caagagaaga tataaaaata cttagagagc ctaaaaaatg tgatggctgt
     4441 ggtggtaaat gtaaggataa tgatggatta gatgaagcca cactaagaga gctaaagaaa
     4501 ttagaagatt aaatttaagg tagggctttt cctacctttt ttaaagcaat taatgcttaa
     4561 agttattaat atttgaggag aatttatata tgcaattaaa agattcagaa agaatagatg
     4621 atttacaatt aaaaggcctt aaaattatac aagatactaa tggtttttgt tttggtatag
     4681 atgcagtttt attagccaat tttactaaaa taaaaaaaga tgccaaagta gtagatttgg
     4741 gtactggaac tggaattata cctattttga tagctggaaa aagtgaagct aaaaaaatta
     4801 ttggcgtgga aatacaagaa gatgtatatg aaatggcaac tcgttctata aaattaaatg
     4861 gattagaaga aagagttgag attataaatg aagatataaa atacatagac aaagtcttag
     4921 acataaatgg ttaccatgta gtcacatcaa atcctccata tatgcatatt gatggaataa
     4981 aaaatccaaa tgataaaaaa gcaatatcaa gacatgaagt aaggtgcaat ttggaagatg
     5041 taattagagc ttcatccaga ttggttatgc ctagaggaaa attcttcatg atacatagac
     5101 caacaagatt ggttgatata ataactttag ggagaaaata taaattagaa ccaaaggtta
     5161 ttcaatttgt gcatccaaga cctcaaaaag caccgaactt agttttggtt caatttgtaa
     5221 aagatggaag accagagctt aaaatattgg acccattgta tgtttatgga gaagatggga
     5281 attatacaaa agaattaaaa gcaatatata ataataaaga tataggagag ttgtaaatga
     5341 gtgggaaatt gtacatatgt ccaacaccaa taggaaacct agaagatata acatatagaa
     5401 ctttaagaac attaaaagaa gtagacttga ttgcagcaga agatacaaga catagtataa
     5461 aacttttaaa tcattttgaa atctcaaaac cactaactag ttatcatgaa cataataagg
     5521 attcaaaggg agattatttg ataaataaac taattgatgg tgaaaatata gctctgataa
     5581 gtgatgcagg tatgcctggt atatctgacc caggagaaga gataataaaa caagctatac
     5641 aaaataacat agagatagaa gtattgccag gtgcaacagc ctttgtaacg gctttagttg
     5701 gctctggtat ggacacacat agatttgttt ttgagggctt tttagataga gataaaaaag
     5761 ttaggaaagc acaattggaa gaattaaagg aagaaagtag aactataatt ttctatgaat
     5821 caccacatag attgaaggat acactaaaag atatgcttaa aattcttggt aataggaata
     5881 tttctataaa tagagaactt acaaaaaaat atcaagaaat aataagagaa aatatagaaa
     5941 ctaccataaa aatatttgag gaaaaagaag taagaggaga gtttgtatta atagtagagg
     6001 gttttcatgg tgagaagtca aagaaagaaa attatgatgg gcttacagat agggaatatg
     6061 ttttaaaact aattgaaagt ggtatgaaca aaaaagatgc aataaaaata gtttgtaaag
     6121 atagaaagtt aaagaaagat gtggtttata aacaagtttt agatttataa aacctgaatc
     6181 tgaggtgatt ttatggaaat agggaaaatt ataatagaga gtttaaagag ggaagataca
     6241 cataaaatat ttatagaatt agataataag catgaattag aaaaaataat tcctaaaata
     6301 agctgtatga agtctgtagg tgaatgtaaa tatcatgtag taaattgttt tgaacattct
     6361 ataaatgcat taaaagaatt agaaatagta ttaaatgata aggatttttt tccaatacat
     6421 ctaagaaaac atgtgtcaaa ctatttaaac acatatattg aagaaggaat aaataagtta
     6481 catgtattaa agttgggaac atttttacat gatataggta agcctgatag tatgacctta
     6541 gatgaaaccg gaagagttca tttcacaaat catgaaaaaa taggtgctca aataattgac
     6601 aatatgggaa taaagttaga gttatcaaca gagacatata gacttataag taaatatgta
     6661 agatatcata tgatactttt gtctctatat aagaaaaatg atttgagtag gaaagaatta
     6721 attaatgtat ttaacttagt agatgaggac actataggtg taataatgct tgggtatgca
     6781 gatatagtgt ctacagtaaa attattgggc aagagtggag aagtcagtgt gttaaagaca
     6841 tatatggaat atattttaac aaattacttg tataagagta attatacaca tgtataaatt
     6901 tagttaatat aattgagttt tagatgatta attgaagttt gaaatatacg gatttcaaaa
     6961 acataaaaga agttgtcttt gttgtaaaat tatgaaagac aacttttttt atatcaaaaa
     7021 ttgaaatttt attaaggata cttaatggtc tattaattaa taaaccatta gtatttaatt
     7081 tatattacaa tattgatttt gcttgtattg gcgttgatag tataacagag gtcttagtag
     7141 aaccaatttt ctttatagta tcaatcacat tttctagctc gtacatatct tttacaatta
     7201 cttttaaaag taagcaatca tcacctgtta tatggtgaca ttctacaatc ctagggtcct
     7261 ttgcagctga ctcaataaat tctgtatatc cattgcttgg aagagaaata tgaataaatg
     7321 cctttataac tctgcctaat gaatctgggt tgacaatagc tttatatcct tctataacac
     7381 cagactcttc taatcttttg actctttctg aaactgcagg agaagttaaa ccaactattt
     7441 ttcctaagtc cttcatagaa attctcccat catcctgtaa aatttctatg attctgtaat
     7501 ctgtaacatc cataaataaa cagtccccct taaataaaaa taattaatac tataaaactt
     7561 ttttagaatc tatcatttgt gtttttaaat accaaagatt tctagataaa tcaaccttat
     7621 aaatgtgtgg ttttgaaagt cttttgtatt gttcccagat agtacttaat tcatattgta
     7681 catgattttt tatttcaaga acagcttttt tattatattt gcatctgcct tttatataca
     7741 atggtttaag aagctcttta actttgtaat ttgtaaatac ctttgttttc catgtataag
     7801 taggatggaa gatttctaaa ggtttagact catctataac ttcatcatgt aacataatca
     7861 aatctgcctc tgccttattg tcttcgttat atattcttat aactttcttg taaccaggat
     7921 tatttatttt ttctggattc tcagaaatct ttatcttagg ttcaagaact cctttttcac
     7981 aagatgcagc taatttataa actcctccaa gagaaggtga atcgaaagat gtaatgagct
     8041 ttgtacctac tccccatgaa tttatagtag ctccttctgc tttaagtgat gttatggtat
     8101 attcgtctag gtcattagat gcagtgatgc tgatatctga aaagccagcg ttatctaatt
     8161 gttttttagc ttctttagat aaataagcta aatctccaga gtcaagtctt atacccatag
     8221 gtttgtatcc tttttcagaa atatttttga atacttttat tgcattagga actccactgt
     8281 ttaatacatc ataagtatct acaagtagta ggcatttatc tggataaaca tcagcatatg
     8341 cttggaatgc ttcaagttca ttatcaaatt tttgtaccca actgtgagct tgtgtaccaa
     8401 ttataggtat atcaaacatt ttccctgcta gtacgtttgc agttccagca caaccaccaa
     8461 ctacagcagc cctagctcca tatatccctg catctggacc ttgtgcacga cgtaatccaa
     8521 attcaaatac agggtctcct tgagctgcaa agcaaactct agaggcttta gtagcaataa
     8581 gagactgaaa attaactatt gttaacaatg ctgtttcaat aagttgagct tgatataaag
     8641 gtgccttaac agtaattaat ggctcattag ggaacatgat agttccttcc tcaacagcat
     8701 atatatctcc tgtgaattta aattctttta aaaattttaa aaacttgtca gaaaataaat
     8761 ttaagttttt taagtactct aaatcttcat ctgaaaaatg aagattatct atgtattcaa
     8821 caacctgatc aataccacaa actatagtat accctccatc acaagcgttt tttctaaaaa
     8881 acatatcaaa tacaacaatg tcttcatgaa tattcttttc aaaatagcca tttaacatag
     8941 taagctgata taaatcagta agaagtgtta gatttctcat tatttctctc cttaattatt
     9001 attaaatatt aaaaattgta aaaactccca cacttatact aaaacataat atagtacaac
     9061 tttcaagtat aaagtattac ctaactatca taaaattatt taaagaggag gatgattata
     9121 ataggaaaaa tatggtttta tatggtatcg ataggaataa taggaagctt gatttctaaa
     9181 aatatgggtg aattaaataa agttatatta agtgaaacat caaaaggtat agagtttgca
     9241 ataagtctag ctggtatcat ggcactctgg atggggataa tgaatatcgc aaaagaatca
     9301 ggtttaattg aaaagatagg tcaaaaacta aatcctataa tgagaagatt atttccttct
     9361 attccaaagg gtcataaagc aatgtcttat atagttatga atattgcttt aaatatgttg
     9421 ggtgctggaa atggtgcaac agcatttggt ttaaaagcaa tgagtgagct tcaaactttg
     9481 aataacaaga aagatacagc cactaatgat atgattatgt ttatggtaat caatatatca
     9541 tctatacaaa taattccatt tactataatc aaattaagga tggatatggg ggctcaaaat
     9601 ccaagtgaaa taatttttac gactttattt gcaaccataa tatctacagc agtagcaata
     9661 ataacatgta aattttttca aagaagatat agataaaggg gatgtagata catggagata
     9721 ttttcaaact tacttatacc aataataatt ctgtacatag tagtttatgg taaatataaa
     9781 aaaatagatg tgtatgatag ttttgtaaaa ggagcaattg atggattaaa agcagcatgg
     9841 gatatcctac catatataat aggtatattt ttggcaatag gaatattcaa aactggtaaa
     9901 ggtcttgata tgttagaatg gctatttaca ccaatagcaa atatgatgag tataccaaaa
     9961 gaattaatag gtctaataag tgtaaaacct ttatctggaa gtggtgcttt agggatgtac
    10021 agtgaacttg caaatagagt tggaatagga agtttagtag aaaaaatggg tgctacgatt
    10081 gtaggttctt ctgagactat tttttacaca atggcaatat actatggaag tctgaagata
    10141 aaaaatacta gacatacatt atcatgtgct atgattagcc atgttgcagg tgtcatagca
    10201 gctgttttta tttgctatgt aatatttgta taatttgttg acaatatggg aaaaatttta
    10261 taatatagtg attatataga aacaaatagt aatacaaatt acaagctatg aaaagaagag
    10321 taaataaagg ttttttctat cagagagcta ggttaggtga aagctagtgt caaaagcttt
    10381 attgaagatg gtcttggagc tttttatctg agcaagtgtg ctagggtaaa acggttggac
    10441 acgttatagt ctactaaggt atctataaaa tgtttctaca tttcatgtga aacataacta
    10501 ttatagatga attagggtgg taccgtgaat aatctcgccc ctatgttaac tcataggagg
    10561 cgatttttta ttatttaaat gaaagaatca tatgattacg aacgataaaa aattaggagg
    10621 taaataacat gagcaaaccg agtttttatg taacaacacc aatatactat ccaagtggag
    10681 gattacacat aggacatact tattcaacag tagctgcaga tacaatagct agattcaagc
    10741 gtttctgtgg atatgatgta aagttcttaa caggaacaga tgagcatggt gaaaaaattc
    10801 aaaagaaagc catagaacaa ggaatgtcag agatagagta tcttgatgga atgataaaag
    10861 atataaaggc cttatggaat actatggata tatcttatga tgattttata agaactacag
    10921 aaaaaagaca tacagacata atacaaaaga tatttactaa actatatgag caaggtgata
    10981 tatataaagg tgaatatgaa ggtagatact gtactccttg tgagagtttc tggacagaat
    11041 ctcaattact agaaggaaat aaatgccctg actgtggaag agaaacatat ttagtaaaag
    11101 aagaatctta tttctttaga ttatctaaat atgaagacag attaaaagag ttatttaaag
    11161 atgatagttt ctgttttcct gctgctagaa aaaatgaaat ggtggcaaac tttttagaca
    11221 aaggattaga agatttaagc gtaactagaa cgacttttga ctggggtata aaagttcctt
    11281 ttgatgaaaa acatgtaatt tatgtgtggg tagatgcttt atgtaactat ataacagcat
    11341 taggttatat gactgataat gatgaagaat ttaaaaaata ttggcctgcc aatgttcaaa
    11401 tagtaggtaa agaaatagtg agattccata caataatatg gccagcgctt ttaatggctt
    11461 taggtctaga agttccaaaa caagtatttg gacatggatg gatactattt gctgatgata
    11521 aaatgagtaa atcaaaaggt aatgtggttt atccagaacc tataatagaa agatatggaa
    11581 tagacacact taagtacttc ttattaagag agtttgcatt tgggcaagat ggaagttata
    11641 ctcatagaaa ttttgtaacg agaataaatt atgatttagc aaatgattta ggaaacttaa
    11701 taagtagaac tgtagctatg gttgaaaaat acaataatgg tataatacca acagcaaaag
    11761 tttcaactga ttttgatgct gacttaaaag aacaagctgt ttcaactaga gaaaactttg
    11821 aagctgaaat ggataaaatg caattccatg aagcattaga gagtgtatgg aaattagtta
    11881 gaagaactaa caaatatata gatgaaacta tgccttgggc actagctaaa gatgaaacga
    11941 agaaagatga attagacaca gttttatata atttatgtga atctataaga ataatcgcaa
    12001 cactaataaa tcctataatg aatgagactg ctaataaaat atatgaacat ataggaataa
    12061 aaggtcaaga tgatataact acatgggaaa gtacaaaaac atttggtctt attggagaaa
    12121 atgtaaaagt atttaaaggt gaacctttat tcccaagatt agatgtagaa aaagagatag
    12181 aagaattaac taaaatgttc tctgggaaac ctccagtaga agaaaaacct ttagagcata
    12241 aagaagaaat tactattgat gatttagaca aaatagagct tagagtaggg aaaataataa
    12301 gctgtgaaaa acatccaaaa gcaaataaat tattagtatc acaagttaag attggaccag
    12361 aaacaagaca aatagtatca ggaatagctg aatactataa gccagaggat ttagtaggaa
    12421 aagaggttac agtggtatgt aacttaaaac cagttaaatt aagaggtgta gaatctcaag
    12481 gtatgatatt agcagcaggt gatgatggag acccatatgt tttaccattt acacaagggg
    12541 ctaaagatgg atgcgaggtt cgttagtagg taattaaata gtaaggagat taaagatgtt
    12601 atttgactca catgcacatt taaatgatga aagttttgat gaagatagag atgaacttat
    12661 tggttcatta aaagataaag gtgtagattt ggttgtaaat ccaggagcag atatagagac
    12721 gtcgataaca gcaattgaac ttgcgaaaaa atacgacttt atatattcag cagttggggt
    12781 acatccacat gatgtatcaa aactagatga tacagcaata gaaactctaa gaaaacttgc
    12841 aactgagaat gaaaaagttg tagctattgg agagattgga ttagattatt attatgatta
    12901 ttctccaaga gaagaacaaa aagagtggtt taagaagcaa attgaattag ctaatgagct
    12961 aaaacttcca ataataatac atgatagaga tgcacatgga gatacttttg agataataaa
    13021 gaatactaaa aatcctgaaa taggatgtgt acttcattgt tatagtggaa atgtagagtt
    13081 agctagagaa tatgttaaga tgggttgtta tatatcaatt ccaggcacgg ttacttttaa
    13141 gaataataaa aaaactagag aagtagtaag agaaatacct ctagaaagat tattcataga
    13201 gactgattca ccatatatgt caccagagcc acatagagga aagagaaaca atccttctca
    13261 agtatctttt gttgctgata agatagccca ggaaaaaggg atatgttatg aagaagtatg
    13321 tagagttaca aaagaaaatg caaagaaatt ttttaatata aaatagacaa attaaatctt
    13381 ataatgatat atataataag tcattataag tataggatga gagtgcctca aaatgagttt
    13441 tttagttcat gaggcactct ttttttatga aatcaaatat attttcatca tttcaacaat
    13501 gaaaaagaag tttatcatat tttgagacag tttgttttta tttgtttaat tcatatttta
    13561 aaatatattt tcttaacatt gttaaaaaag aatttacaag atattcatta gaattaactc
    13621 aactctaata ttcacttaac ttaagtggtt tattatatta ttaaagagaa gtaaacgaaa
    13681 ggtagattaa ggaggctaaa ttttgtatac agttgatagt actaagatat tgataaatat
    13741 gaacttagag aaactagaaa agatatactc aatgataaaa gatacatcaa gtatttctat
    13801 aattaaagaa cctaacttgg ctacagtaat ggtaagagct aatgaaagtg taaaaaatac
    13861 aacatttaat ttaggagaga tattagttac tgaatgtagt gtaaaggtag atgaaagctt
    13921 gggttacgga atagtttcag aaaacaataa taagaaagcc atttacttag cagttataga
    13981 tgcagtttta catagcaata acagtaaatt tgatgagtta aagaattaca taaataaaag
    14041 tgtatatgaa gagaacttaa ggtatgaaca agagattatt gatgaattta gcttgattaa
    14101 taaaacgaaa gttcaattca atgctatgga ttaaatagga ggagaatcat ggtaaattat
    14161 acacaagaaa tatatagaaa gatgctagat agtgcttcgt ttcctgggaa attaaataat
    14221 atagataata taaatataga aaataataca aaactattga atggagcaat tggtatagca
    14281 atcactttat tagaccaaga agttaccttc tatatagaaa attatactca aaaagatata
    14341 aaaaatataa gagcgcttac agtgtcaaat caaatagatt atagaaaatc agattatata
    14401 tttttagata ttaattcaga agtggatata ttacagatta aaataggttc ttttgaatat
    14461 cctgatgaaa gtgcaactat agtacatcaa gtaaatgatt tatcaacgta ctctcaaact
    14521 aagtatataa agcttgattt gagtggtcct ggtataaaat ctaaaaatag tatatatata
    14581 aatggaatta gagaagaatt tatagaaaga ttatctacca taaataaaga ttatccaata
    14641 ggaatagatt tgattttagt agataaaaaa ggagaaattg catttatacc aaggtcatca
    14701 aaattaagtt gggaggtatt gtagaaatgg cttatgtagc agttaaaggt ggagaagaag
    14761 ccatattaca ggctaaaaat atacttgagt tttatagggt aaaaggagat agcttgccta
    14821 tagatgtaaa gcagattgag gaacaaatgt cttatgctgt agacaaagta atgtctgaag
    14881 gaagtttata caacaaggaa ctatcagcat tggctataaa acaagctcaa ggtgatatat
    14941 tagaagcctc tttctatgta agagctttaa ggtcaacaat gcctagaatt acatattcag
    15001 aacccataaa tacagaagaa atgagaataa aaagaagaat atcagctact tttaaagata
    15061 taccaggagg tcagtatctt ggggcaacta gagactatga aaatagaata ttaaatgtag
    15121 aattattaga agaagatgaa aaaaagaata gagattttag agatagtttt ataaatgaat
    15181 tagaaacagt agatgaaatc cctgaattta caaaaatatc taatatattt agaaaagaaa
    15241 atttattaca agaagaagtt tgtgaaaaca aattggaaga agttattgat gatattacaa
    15301 gaaatagttt aagatttcca gtttctaggt cagcaaagtt acaggcattg actagaggtg
    15361 aaagtggagt agtgtcaggt tttgcttatg ctattgtaag aggttttggt gatgaacatc
    15421 catatataag tgaacttaga actggtaatg tatttataaa agtaaaacat cccatctatg
    15481 aagatgaaga aataataata ggtgatatgc tggttactga atgtgaaata gtttcaaaag
    15541 catcacaaaa taagactgaa aattctaaaa ctaattcgga agataaaaat aagatgtctt
    15601 taggatatgg tctttgtatg gggaataatg agaataaggc tatatctatg gccatactag
    15661 acaaatcttt ggagccaaat agtgaaaaac tagcacaaga tgaagaattt gtattgcttc
    15721 atatagatgg aatagattca ttaggattta tatctcactt taagcttcct cactatgtag
    15781 attttaaagc ggatgtagaa agaataaaat agtttgtgga ggtaagttta ggtgatatat
    15841 aactatggtt ttttagacga aaacacaaaa aaagaaataa gaagaaagat attaaaagca
    15901 atatcaatac ctggttatca agttcccttt ggttcaagag agttgcctat agctaaggga
    15961 tggggtactg gaggtttaca attaacacta tcattaattg gtaaaaatga tgtagtaaaa
    16021 gtaattgacc aaggaagtga tgattctaca aatgcttgta atataaggag ctttattgca
    16081 agtgtaagta atgtagaaac cacaaaagat acattagaag ctacattgat tcaaacgaga
    16141 catagaatac cagaagaaaa acttaaatct aatcaaatac taatatttca agtaccaata
    16201 ccagaaaccc ttagaatagt agaacctagt gaagtagaaa caagaagaat gcattcagaa
    16261 gaagattata gtaggatgtg ggtatatctt tatgaagata tagttagatt taatgatata
    16321 tctatagcag ttgaatatcc atgtaaagta aatgatagat atttaatgaa tccatcacct
    16381 atacctagat ttgatataaa aaaattaaat atgtcagaca atttattctt gtttggtgca
    16441 ggtagagaaa aaagaattta tgctattcct ccatatacaa aggtagaacc tttagagttt
    16501 gaggattata agtttgaaga ggaaaagttt gaaggaaaat actgtagttt atgtaacagt
    16561 acaaatacat ttttagatga agtatatgac agtgacacta atgaaaagta ctatagttgc
    16621 tcagatacaa gttattgtga aaaagttaga ttaaaaaata acagtataga tgtgacaata
    16681 ggaggtactt ggaatgagta aaataaatgt ctctaaaaga ttagaaaata tagacaagca
    16741 agtattaata ggaagaaata tcaatcttat ttatggagat gggtgtgaaa agtgttttga
    16801 aagcacagga tatgaaagca ataatatatg taagtattgt ggttctatag ttgcatgtaa
    16861 taatgtaaat ttagaacttt atgaaggaga agtccttgga attgtaggtg aatctggttc
    16921 aggaaaaagc actttattaa aaatactgtt tttccaagaa catgcaaata gtggagaagt
    16981 atatatatcc cattacaata aagacacaaa tatactagag ctttcagacc aaaaaaagag
    17041 atacataaag aatcatttta tgggtattgt gtatcaaaat ccccaccttg gtttaaattt
    17101 agactttagt agtggtggta atatagcaga aaaattattg atggcaaatt tatataatgt
    17161 tgaaaaaata agagatagag gcaaagaact tttaataaaa actaatatac ctgtagaaag
    17221 aatagatcat aaaccaaaat actttagtgg gggaatgcaa caacgagttc aaatagcaaa
    17281 agctctttca aataaccctc caatattgct attagatgag gttacaacag gtttagatgt
    17341 ttctgtgcaa gcggaagtat tggatttaat aagagaaatc caaagagaac ttaagatttc
    17401 tatgatagtt gtatcccatg actttgatgt tataaagatg cttgctgata ggacaattgt
    17461 aatgaaaaat ggaagtgtga ttgagtctgg tcttacagac caaataatgg aggacccaca
    17521 acacccatat actcagcaac ttataaattc attgctataa atatcgtttg taaataagca
    17581 aaatgggggt ttttaataaa atgaaagaaa ctatacttga agtaaataat tttagtaaag
    17641 actttgagtt acatgcattg aacaagacta taacggcatg tagtaatata agttttgaag
    17701 tttcaaaagg tgagttttta ggaataatag gtaaatctgg agcaggtaag tctaccatat
    17761 taaaaagtat ctataaaaca tatataccaa caactggaga aataattttt aattcagaaa
    17821 tatatggtaa tgtagacctg gctaaaattg gagaccgaga aatgataaat cttagaaaga
    17881 aagaaatagg atatgtatca cagtttttaa agacacttcc acgaataact gcaattgaac
    17941 tggtagtaca ttctttaatt gagagtgggt ttgaaaaaga ttgttcgtat gatatggcaa
    18001 aagatatact taaccaattt gaaataaagg aaaatttatg ggatgcgtat ccaaataatt
    18061 tttctggtgg agaaaaatta agattaaatt tagctcaagc tatggttaaa aagcctagac
    18121 ttttgttact tgatgaacca actgcatcac ttgataatca atctaaaata tatgtaaaag
    18181 aaaaaatgtt ggaacttaaa agtcaaggaa ctacaatgat aggaattttt catgatatag
    18241 agtttatgga aactgttata gataagacct ttactatggc aaaagggact ataagtgaaa
    18301 gtggggtagc ctagatgata aaactaattc ataatgcaaa tattgtatta gaagatatga
    18361 ttttagaaaa tggtcattta atcatagagg gagatacaat aaaaaaagta tcaaatgata
    18421 ggattgatta cgcatttgac tttaatgaga tagatgaaat aatagatgca aaaaacttat
    18481 atgtaatacc tggtattata gatattcaca gtgatgccat tgaaaaggaa atagagccaa
    18541 gaccaagtac attattacca tttaatatgg cattttatga actagataaa aaactacctg
    18601 caaatggaat aactacagtt tatcattcta tatctttagg ggatggagta ggagttagaa
    18661 gtattgataa ctctttaaag atgattaaaa atattgattc atataaaaat atagatagta
    18721 agagtataaa tcataaagtt catttaagat atgaagtgtt gtattatgaa ggtttagaaa
    18781 aggttttaga actattagat gaaaataaaa tagactactt atcaataatg gaccattctc
    18841 caggacaagg tcagtataca aatccaacat tttataaaga gtatgctact aaagtgtggg
    18901 gagttacaga aaattatgta gatacatggt tagatgattt agtaaatctg catgataatt
    18961 tagattggaa taaaatagct aatattatag gtatagccaa aactaaaaat ataaatgttg
    19021 catcacatga tgatgataca ttagaaaaaa tggatttcat aaaaaatata ggcataaatg
    19081 tatctgaatt tcctataact cttgaagttg caaaacattc aaaaaaattg ggtgttctaa
    19141 cttgtttagg tgcaccgaat attgtaagag gtaaatctca taataacaat ttaaaagcaa
    19201 tggatgctat attggaagat tgttgtgaca ttgtgtgttc ggattatctt ccatcagcta
    19261 tgataaagtc tatgtgtata gttgcagaaa gaataaataa tttaaataaa gcagtcagtt
    19321 tatttacctc aaatcctgct aaagcagttg gtatatatga tgaaagaggt agtataaaag
    19381 aaaataaaaa agcagattta gttttagtag atattgatag tgaatatcca aaggttttaa
    19441 atactattgt aaatggaaaa acagtttata aaagggaggt ataaaaattg ctaacagagt
    19501 tacattgtca tacaagtata tcagataata attttactac tgaagaaata ataaaaaaag
    19561 cagcagaaaa gaatataaat atcttagcaa taacaaatca tgacacatta tctggattgg
    19621 atgaagctct tgtgcttgga gagcattatg gaataacaat aataccaggt atagaaattt
    19681 cagcctatga ttataaaaat agaaaaagag ttcatattct tggatataac atagatttaa
    19741 acagtcaaga aataaaaaat ttgtgcaatc caatggtatg tgacagacat aaagcatctg
    19801 ttaagatggt aaataaaatt atagatttag gatacaaaat atctttggaa gatgtaaaga
    19861 aatattcatc aaagactgga atatttaaac aacatataat gaaagctctt atagataaag
    19921 gatatacaga taatatatat tcaagtctat ataaagaatt gtttcataga ggaaacggca
    19981 aggtatatgt atctttaaaa tatgtggatt acagagatgc aataaaagct ataaaaaatt
    20041 ctggtggaat ttgtgtgtta gctcacccgg gtcaaatgga taattttagc gctattgaag
    20101 agatggtaaa agtaggatta gatggaatag aagtatatca tccatctcac aacaaagaac
    20161 tagaaaaaga gtcgctttct tatgctaaga agtataatct agtggtcaca ggaggctcag
    20221 attaccacgg attttattct caacataatt atgaacttgg aagcaagagc ttaaataaag
    20281 aagatttatt taagtttagg ttagctttag gaggggtatt ataaatgtct tttttacaag
    20341 taaaaaatgt aggtaaaagt tatggacaag ttaaggtgtt aaaagacata tctattgata
    20401 ttgaaaaagg agagtttatt tgtttactag gtccaagtgg ttgtggaaaa agtacactgc
    20461 ttagaataat tgcagggctt gaggataaac atggtggaaa aataataata aatgataagg
    20521 atatgactaa ttcaccacct gaaagtagaa attttggtat agtttttcaa tcatatgcat
    20581 tatttccaaa tatgaatgtt tacaaaaaca tagcctttgg actagaaaat aaaaacataa
    20641 gtaaatctaa tattgataaa aaagttaaag aagttctaga cgttgtagaa ttaagtggat
    20701 atgagaaaaa atatccatca caattatcag gtggacaaca acaaagggtt gcattagctc
    20761 gtgcgattgc tttagagcca gactttttac ttcttgatga acctttatct gcattagatg
    20821 caaaagtaag acttaaactt agggagcaga ttagaagttt acatagaaaa ctaggcatta
    20881 caactataat ggtaacgcat gaccaagaag aagctctttg tttagctgat aagatggttg
    20941 ttatgaatag aggagaaata atacaagttg gaacgccaaa ggaggtatat aaaaatccag
    21001 aaacaccttt tgtagctgat tttataggaa caataaattt tatagatgat ggtattaata
    21061 agatagctat tagaccagaa gatataaaag tagagtctaa tagagattct aaagataagg
    21121 atataaaagt gggagaaatt ttagatatcg aatttagagg atttaactat agaattacag
    21181 ttgagtatcg ttctaagcaa atgaaattag atgtagtttc caaagttgca gaacaaatga
    21241 aactgtgcat aggttctaaa ataaacttta agatacctaa agaaggaatt gtacaatata
    21301 aatcagaggg atgtgcttaa tagctagggg tgaataaatg ataacatcaa aaaataaaag
    21361 aagaataagt gatagcacaa tacaaaaata tttcttgatt ttttcggtaa ttgtactaat
    21421 agtatttata ttatttccat tagtatcatt attaaaaaat gcatttatgg atacaagtgg
    21481 aaattttata ggaatttcaa actttagtaa atatgttgaa aatccaagtc ttatagcatc
    21541 atttaaaaat tcaatttttg tatctacagt ctcatcttta atatcactat gtttagcatt
    21601 tatatattca tacgcaataa caagaacaaa tataaagttt aaagattttt ttaaaactat
    21661 gggaatgttt ccactttttg caccaactat gttatatggt atttcactta tatacctttt
    21721 tggaaataag ggaatcttta caaccatggg tctggaagta ccactatatg gtccattagg
    21781 aataattatt tctcagattc tatttacatt tccacaagct tttttaatat tatctgtagc
    21841 actttcgatg gctgattata gactttatga agcagcagat agcttgggtg ctagtgaatt
    21901 taagaaattt tgcaaaataa caattcctgg tataaagtac tcattactta gttcattctt
    21961 tgtatccttt atacttgcat ttacagattt tggagcagct aaggtagtcg gaggaaacta
    22021 caatgtactg gctactgaca tatataaaca agtagttgga caatttaaca taccaatggg
    22081 agctactgtt tctatggtaa tgttaattcc tgtactaata gcatttacat tagataagat
    22141 ggcaagtaag aaacaaggta tgaccataac tgcaaagtct atgccatata agattaagga
    22201 aaataagttt agagatagag tatttttaat agtatgtagt tttataacat tgctaatttt
    22261 tattttaata ttcgtttcag ttataggttc agttataaag ttatggccat ataatttaag
    22321 ctttacaatg gaacactata catttaaagg tattttggga agtggaataa aaacatactt
    22381 aagcagtttg aaaatatcaa ctttaacagc aatatttgga actatatttg tattttttag
    22441 tgcttatata atagaaaagg tggataagtt tcctaaatta agacaaacag cttacctttt
    22501 atcaatgata ccaatggcct tacctggctt agttttaggt atatcatata taactttttt
    22561 taactcagca agtaatccat taaatttttt atatggaagt acagcaatat tagttatagt
    22621 aaatgtagtt catttttatt cagtttgttt tataacctca aattcatctt taaaaatgtt
    22681 ggataaagag tatgaattag ttgcaaaatc tataaatatt ccattctata aagtattttt
    22741 taatataaca gttccgatgt ctataacatc aatacttgaa atagtagtat attattttgt
    22801 aaattcaatg gttactgttt cagcattaat atttttatat atacctcaaa ctcagactgc
    22861 atcaatatca atactaaagt tagatgagat aggatatata ggaccatcag ctgctatggc
    22921 agtattagtg ctattaacaa atataatagt aagacttttg tacgaatttg taacaaagaa
    22981 attaaaaaat aacacacaaa aatggcagca aaaagatgtt gcatagggga ggaaaaaatg
    23041 aaatttaaaa agctagtttc tttaggagta ttatcaacac ttttattaag tgtaataaca
    23101 ggatgtagta ctgattcatc aggttcagat tcaaagtctg atagtaagac aaaaggggat
    23161 ttaacagttt acacagcaat tgaagaagat agtatagagc catatttagc tacatttaaa
    23221 gagaaatatc cagatattaa attaaatatt gttagggcat caacaggaga tataacagca
    23281 agattattag cagaaaagga taatcctcaa gcagatgttg tatggggagt tgcagccaca
    23341 agcttattgg ttgcagatga ccaggggatg ttagaaccat atgctccaaa aggttctgaa
    23401 gaaatagagt ctgcatttaa agatgataaa gaagttcctt cttgggttgg gatagatgct
    23461 tggatgacag gtataacagt aaacactaaa gaattaagtg ataagaacat cccagttcct
    23521 agttcttacg aagatttaat aaagccagaa tataaaggtc ttatatctat gcctaatcca
    23581 tcttcttctg gtacagggta cttaacagta tcagccctta tacaaattat gggggaagaa
    23641 aaagcatggc agtatatgga taagttgcat gagaatattg gtgtatacac tcaatctggt
    23701 tcagctccag ctacatcagc agcttcagga gaatatccta ttggtatatc ttttggatat
    23761 agaggtataa aattaaaaga ggaaggctat ccagtagaag tagtatttcc aaaagaaggt
    23821 tctggatggg atatagaagc aaatgctctt gtgaaaaaag ataatataaa agaagcatca
    23881 aaagtatttt tagattgggc tataagtaaa gatgcaatga atgaatactc taagaactat
    23941 gcagttacta ctatttctac aggaaatcca ataccagaag gattccctaa aaagccatta
    24001 gagcaaatga tagataatga tttaaaatca gcagcaaaaa atagagaaga tatactaaat
    24061 aaatggatat caaaatatga tggtaagaca gaaaaagaga gttaagtaaa actatacaaa
    24121 tggagtaaaa agaaaaaatt tttttaagta gattttatta taataatata agttgagaat
    24181 aatataggtc aagaaaagtg aatattctat aaaaatgtat agagtaagta taccattcag
    24241 tttgaatggt atatttttta tttttagaga ttaatttaga aatagatata ctacagttta
    24301 aaatagtata ttttaatttc attattaaag tatagatgtt atatataaag taaataagat
    24361 attaaataat tataaactaa agtaaataaa atattgagcg attattaaaa agatatatat
    24421 atatatttta atttgagcag tttgttatat attataaaaa aagagaaaaa taaaaggtaa
    24481 attgtttctg gataacttaa aattggaagt aagaatattt aactagagaa gaattattta
    24541 agttcaggtt agctctagga gtagctgatt ttataggagc aatagatttt atggatgatg
    24601 atataaacat gatagcaatt agaccagaag atataagggt agaatttaat agagatttca
    24661 aagaaattat agacctcaaa ctcagaccgt atcgatataa aaactaaagc tagatgatat
    24721 agtgttgtat ataggaccat cagctgttat ggaagtatta gtgcttttaa caaatataat
    24781 agtaaaactt ttgtatgaat tgataataaa aaaattaaaa accaagacat aaaaatggca
    24841 acaaaaagaa gttgaataag ggaggtaaaa atgaaattta agaagttagt ctctttggga
    24901 atattatcaa cacttttatt gagtgtaata actggatgta gtaatgtttc atcaggttca
    24961 aacttaaagt ctaataataa gacaaaagga gagttaacag tttatacagc aattgaggaa
    25021 gatagtatag atacatactt agctacattt aaagagaaat atccagatat taaattgaat
    25081 gtacttagat tatcagtagg aggtataaca gcaagattat tagcagaaaa agataatcct
    25141 aaagcagatg tgttatgggg tgttgcagct acaagtttga taattttaga tgacaaagaa
    25201 atgctagagc catacgctcc gaaaggcttt gataaggtaa atcctgcatt taaagatgat
    25261 aagaaagttc cttcttgggt tggaatagat gcttggatga ctggtataac agtaaatact
    25321 aaagaattaa aagctaaaaa catatcagct cctaattctt atgaagattt aataaagcca
    25381 gaatataaag atcttatatc tatgcctagt ccagcttctt caggaacagg atatttaaca
    25441 gtatcagaac tcatacaaat tatgggtgaa gaaaaagcat ggcagtatat ggataaattg
    25501 cataaaaata ttggtgtata cactcagtct ggttcagcgc cagctatatt agcagcttca
    25561 ggagaatatc ccattggtat atcttttgga aatagaggta taaagttaaa aggtgaaggt
    25621 tatccagtag aagtagtatt tccaaaagaa ggttctggat gggagataga atcaaatgca
    25681 cttgtgaaaa aagataatat aaaagaagca tcaaaagtat ttttagattg ggctataagt
    25741 aaagatgcaa tgaatgagta ttctaagaat tttgcagtta ctacaattga cacgggaaat
    25801 ccggtgccag aaggatttcc aaagaatcca ttagaacaga tgatagataa tgatttaaaa
    25861 tcagcagcaa gaaatagaga ggctatacta aataaatgga tagaaaaata tgatggaaag
    25921 acagaaaaag agagctaagc cttacaataa aatttagtac aaaaagcgcc tagaatataa
    25981 gttttacatc taggctcttt tgatatattt atttaaaatg catatttcta tataaaaata
    26041 aatagtttag taccttgatt aaattaaata aaaaccttaa aataaagaga tgtaaagaaa
    26101 aactaaaaac gaataaaagg tgaatttata tgataaaaga aataatagta gtagagggta
    26161 gagatgacgt tacagcagtt aagagagcaa tagatgcaga acttataact acaggtggat
    26221 ttggatttcc aaaaggtgta atgcagcgta taaaagctgc taatgaaaga cgtggtgtta
    26281 taatatttac agacccagat tttgcaggtg aaaaaataag aaaaaaaata gcatcagaag
    26341 ttccaggatg taaacatgca tttctaccaa gagaggaagc taaaaaggat ggagatatag
    26401 gtattgagaa tgctactcct caaagtataa tagcagctct gaataaagtt agaactgaaa
    26461 atacagaaaa aagagatgaa tttaagcaag ttgacttaat tagaaatggt cttataggta
    26521 atgaagaagc atcacttaga agagatgcac ttggaaaaat acttggaatt ggatatggaa
    26581 atgcaaaaca atttttaaat agattgaata attatggagt tgaaagagaa gaatttatag
    26641 atgcattaaa acaaatctaa acgtaatgtt taatgtatga aaaatatgta tataaaataa
    26701 attgtggaat tacggttaat ttaagataaa ttatttataa tatatacctt attttaaatc
    26761 aatgtaaata catataaata agtataatta ataaaattaa atatcaaaat aagttaaaaa
    26821 ggagtaaata atggatagac tatcttcaca taatgcaaca aaggaagtag tacaaaaata
    26881 taattttaaa ttttcaaagt ctttaggtca aaatttcttg atagatagta atataattga
    26941 taaaatctta tctggagcta gaatcacaag aggagataat atcatagaag taggacctgg
    27001 tataggaact cttactcgtg agatgggtaa aatagcagaa aaagtagtgg ctatagaaat
    27061 cgatagaaat ttaattccta tattgaaaga taccttgtca gatttagata atacagaggt
    27121 tgtaaatcaa gatatactaa aagtagacat acaggaatta gtaaaagata aattaaatgg
    27181 tggaccagtt aagcttgtag caaatcttcc atattatata actactccaa tagttatgaa
    27241 atttttagag gaagacatac ctgtaacaga catagtagtc atggttcaaa aagaagttgc
    27301 agatagaatg aatgctattc cgggtactaa agattatggg gcattatcta tagctgttca
    27361 atactattgt gatacagaga ttgtggcaaa agctccaaga catatgttta taccacaacc
    27421 aaatgtagat tccacagtta taggtttaca tgtaagagat aaaagaaaat atgatgttca
    27481 taatgaagac atatttttta aaacagtaaa agcatccttt ggacaaagaa gaaaaactct
    27541 tcttaattcg ttgggaggtc ttggttttct taataaagat gaaataagag aaatattaaa
    27601 agaagctaat atagacgaaa aaagaagggg tgaaactctt agtatagaag agttttcagt
    27661 tctttcaaat ataataaata caaaagtatc ttctaaatag aaggtacttt ttttaatttt
    27721 gttaacatat attgtttaga gaaactgtgt taagggggga ttgcagtggg ttctaaaaga
    27781 aagtttaaaa gagactatat aatactagaa gctaaagaca taaactttag atacaaagaa
    27841 cgagtactgc caaaagcttt tgcaaaagtt gaagtaaatg atgaaaaagc aattattgca
    27901 ttatatgtag aaaatctaaa atatgttaaa gatgggtata aagcagtagc aataaaagat
    27961 gaccatggat taatagactt aggaaatata attttaaatg aacaaggaag aggtgaattt
    28021 gttttagatt tagaagattc tgatgatgag ataaaaggta ttgcattatt gtatgaaaga
    28081 aatatacctt taattggatt taagggaaat aagcttgaaa attatgagga catattattt
    28141 caagaggtag aggaagaaga atatgaagaa tatgaagaat atgaagagtt ggaagaagac
    28201 gaagagatag aggataatga ggaaagtgat agagacgaag atagtgaaga agaatatatt
    28261 atagaagaat atgatgaaga tgagtatgaa gactattggg aagatgatga agatattgaa
    28321 gaaggagagt taaaagcaag aacggaagta gaagattctg gtgatgagga aatagaagag
    28381 ttcaataatt ataaggaaat agaaaattat aatagggtta aagtacagga agaatatata
    28441 gacatagaat atgatgagga agaagaggaa gaagaagaag tttttgaagt aaatagagaa
    28501 gaagataggt ttgtttcctc aaaacctact aaatcaaaga aagttcaaaa agatcagaat
    28561 aatattgaaa aaataaaaag agctaatgga gtaagtcaag gagagagtgg aaataaacaa
    28621 accagtacat tacttatgcc aagacaaata aaaaaaggtt tgaaattatt taaagaagta
    28681 aaaccttttg taacagatta tatagataag acaagatggt ggaaaataga gataaatcct
    28741 acaacactgt gtggatatac aatgccttat ttaggatatt taaacgtatt gaattacact
    28801 atgtatagtg atgcagtttt acattcatat aaatacagac actatttatt tggtgttcag
    28861 tatgatgaat ataataagag aaaacattat atttatgcta tcccaggaaa tagaaatgaa
    28921 cagccagaca atggaagcac aggattttta agatatcaag cttgtgataa tagaacaaat
    28981 agtttaggat attggctatg ttttatagat tctagacaaa gaaatatagt taggtaaaaa
    29041 taataaaaat gaaaaaattt agactcaatt cttattttac tgaaaaaatt aatgaaatgt
    29101 agtacaaaac tttaaaaact attgataata tttaaatatt acactacaat atatcttgaa
    29161 atacctatta tattatggag gaaaattatg ataaacgagc aaagaatttt aaatgagttt
    29221 cttgaattag tacagataga tagtttatct ttaaaagagg ggaatgttgc taaagtatta
    29281 gttaaaaaat tagaagaaat aggttgttca gtagtaatag acaatgctgg tgaaaaagca
    29341 aatggagaaa ctggtaatat aatagctaca ttaaaaggaa ataaagaagg aaagaaaata
    29401 ttatttagtt cacatatgga tacagtaact ccaggtatag gggtaaaacc tatagtggat
    29461 gaagcaaatg gaataataaa aagtgatggt actacaatat taggttctga tgataaagca
    29521 ggtatagcag ctatattaga aggcttaaga tatataaatg aaaataacat agaacatact
    29581 gatatacaag ttgtattctc tatatgtgag gaatgtggat tagttggagc taaaaattta
    29641 gactatggaa aaatagattc tgaatatgca tttatattag atagtggtgg ttctccaggt
    29701 gaaataatag taaaagctcc tgcacaagat gtaataaatg ttaagatatt aggaaagact
    29761 gctcatgcag gtcttgaacc tgaagctgga ataagtgcta taatggtagc tgccagagca
    29821 atagaaaata tgaatttact tagaatagac gaagaaacaa ctgctaacat aggaattata
    29881 aacggtggaa cagctacaaa tatagtaaca ggagaagtta atatagttgc agaagccaga
    29941 agtctaaaag aaaataaatt agatgttcaa actaaacaca tggtagagac ttttgaaaaa
    30001 gctgcaaaag attttggagc tcaaattgag atagatgtca atagagcata tacaccaata
    30061 gatgttagtg aggattctga aataataaaa cttgcaaaga aggctttttc aaacttaggt
    30121 atagaaggtc atactgaatc tacaggagga ggtagcgata caaatatatt aagtaagaat
    30181 ggtatcgaag ctataacttt aggaattggt atgaaaaatg ctcatacact aagtgaacat
    30241 atagctataa aagacttata tgactctgct aaaatggtag tggagataat aaaggaagca
    30301 taaatttaaa taatagtgta taatatatat atcgcctagc ttaagctagg tgatttttca
    30361 ttttatagaa gattgataat ctctattgaa agcaaagagt atacatttgc atataagaga
    30421 gtgtttaatt tatgttcaga tgtaggttct taataatatt tagattgttt cataagggag
    30481 gaataaatat ggaaacaagg tatgaagaag caaataaaat aacaatacaa tcaatacttt
    30541 ggaatgtagt attaacaata attaaggtta tagctggtgt tattggtaat tctagcgcta
    30601 tgattgcaga tggattacat tcagcatcag atattataag ttctatagga gtactaatag
    30661 gcaattatgt atcttctaga cctggagata gagagcacaa ttatggtcat gagaaagcag
    30721 agacattagt atcatttgtg ttatcaatat tgcttatttt cgtttctata acaataggta
    30781 tagaggcaat taaatcttta tttaacttag atgcattaag tgttccatca atattaccat
    30841 tagtagtatc agttatttca atcctgataa aagagtatca atatagaata acaataaaag
    30901 ttgctaaaaa gataaattca ccagccttaa aagctgatgc ttggcatcat aggtcagatg
    30961 ctttatcttc agtagctgct tttataggta taggtggttc tattttaggg tttaagccac
    31021 tagacccaat tgcgtcaatt gtagtggcta tatttgtagc taaagtagga attagtatac
    31081 ttataagttc tgttaatgaa ttgatggatg tttcagttga cgaagaagag ataaaagaat
    31141 taaaatttat tgtagcagat acagaaggtg ttaaaaatct tggtgatata aagactagaa
    31201 aacatggagc tatggcatat gtagatttga ctatatgtgt ggatgaaaat ttgacagtta
    31261 agcaaggtca tgatattgct accaagcttg aaaaacatat aataaaacat atggaatttg
    31321 taaaaggcat aacagttcac gttgaaccat gtactaattg ccaaggaaat aagtgtaata
    31381 attaattaaa acttaaaaaa aagtgtaaaa agttatataa ttgttttatg attataaact
    31441 ctaggggtgg ttaaatgagc aagaaaagaa aactaaagaa aaaagctgca atattaatag
    31501 gagtagttgt tttctttata atatacttta tatcctttag aataggaata aatatggaaa
    31561 aggataaaag tgaagtgcca aagaaggtag aaaaagaaga agaagataat aggtctttaa
    31621 ggactcaaat aaaagaaaag aaaaaggttt atatatcaga caaaaatata gaaaacataa
    31681 aaattgaaga agatatgtgg gatgaaataa agttattttt ctcagatttt aagaaagtaa
    31741 gaaatactac ttcttcttac gaagcagttt atgaaggtta ttctgatgat ggagttaaat
    31801 tttctactga ccttaacttt tttagagtat atactgtaaa taaagaagaa tattataaag
    31861 taccagttag ttctaaggat gcttttaaga aacttttaga tgagagtata tatacttcat
    31921 ttgacctttt aagtcattat aaagattgga aagaggttac tataactcat ggaaaagaaa
    31981 ttaaaaaagt tcatagatgg aaatttgatg atttagcaca taagatgatt tcaaagaggg
    32041 ttgtaggaaa agttcaacct gagaaaagta aggaaagaag tgactataat tttactataa
    32101 atataaaagg tgataatttt gatgtaaaag ttgatacaat gggaaaagat tatgtaaaag
    32161 ttacttctaa gaaaaatgta tcttactatg aggttcatac aagtttattt gattacctta
    32221 aaaatgagat atttgaaatt ggaaagaaat aagactttaa gaaggctatc aaattagata
    32281 tttgatagcc taaattattt ttatatatta tttttcaacc aacaagtctg caaccttata
    32341 aattggacca gcaccagcag ttattactaa atcattatcc ttaacatttt cacgtaagta
    32401 ttttactata tcttcaaatt cttttatata gatggcatct acattgtttt gatataattt
    32461 ctcaaccaag tccttagaat gtatatctcc agggtctttt tccctagcag catatatatc
    32521 tgttatgata actttatcag cagcatagaa tgcctctgaa aattcaccta aaagagattt
    32581 tgttctagta taagtatgtg gctggaagat acaccataaa gttgattttt ttaatttttt
    32641 ggcagcagct aaagttgctt ttaactcagt tggatgatgt gcataatcat ctactactaa
    32701 agcattctta taataccctt tagtttcaaa tcttcttccg acacctttat aaatttttat
    32761 attttttctt atagtctcta agtcaatacc agaaacaaga gctgccatta tagcagaaga
    32821 agcattgtat atgttatgaa gaccatatac agaaagttca aattctccta aatctcttcc
    32881 ttcatattct attctaaata ttccatgacc actattgtca aagtgaatat cttttattac
    32941 agcatcattg tcagaatctc taccgtattt tataatagta gctttaacat catacaatat
    33001 gtcatcaata ttttcatcat cgccatttat tatgaaatag ccttctgggg gtaataattt
    33061 tccaaatttg ttaaaagaag ccttgatttc atctattcca gagaaataat caagatggtc
    33121 ttcttcaaca tttaaaacta tagatatctt tgggttaaaa ttaaggaaac tatctacata
    33181 ttcacatgct tcagttataa agtggttgga attacctatc ttaacattac cacctatcat
    33241 acttaagtta ccaccaacta gtatagttgg gtctaagtct gcatattcaa agattgtaga
    33301 taacatagat gttgtagaag tttttccatg tgttccagaa actgctatag aatttttata
    33361 ttccctcatg atttggccta aaaaagtcgc tctgttcatt accaatttat ttttttcttt
    33421 agcagccaca agttcttcat tgtctggatg aactgctgct gtataaacaa ccatatttac
    33481 atcatctgat atattatctt ttttctgacc aatataaata gttgcccctt ggtccctaag
    33541 tttgtctaat aggtatgatt cgtttgaatc cgaacctgaa acttgataac ctttattgat
    33601 acatatttca gctaatgcac tcatgctgat accgccaatt cctataaagt gtatattcat
    33661 aataaaacca cctttctttt taattaagtc ctacaatatg aactatttat gtggtataat
    33721 aatataatgt tcaatatttt ataattaata tgcatataat attatatgta ttttattttt
    33781 gaatataata aaacataagt aatattatac cacaataaga attgttatgc attagttagt
    33841 ttaacgttat ataaaggtac ttgtaggagg aaataataat gaaatttaaa agaacagaga
    33901 gaattggagc aatagttaaa atactgtctg ataatccaaa taaaatatat acattaagtt
    33961 attttacaaa tcaatttaat gcagcaaaat caacaataag tgaagattta ttagttgtaa
    34021 aaaatgtatt tgagaagcta catttaggta aagttataac tatctcagga gcagcaggag
    34081 gagtaaaata tatacctaaa acttctatag cagaaaatgc agagttctta atggaattat
    34141 gtgagagaat atgtgacaag tctagaatac tatctggtgg ttttttatac ttgattgacc
    34201 taatttatga ccctacaata gctgctaaga taggaaagat attcgcatca aatattgagt
    34261 atgtagatgc agattatgtt gtgacaatgg aaacaaaagg tatacctatg gcacttatga
    34321 ctgcaaaagc tatgaattta cctctagtta taataagaaa agatataaag gtatcagaag
    34381 gtcctacact tagcatgaca tatgtgagtg gaaacagctc taaagttgaa agtatgagtt
    34441 tgccaagaaa agctcttaaa ccagatagta aagttataat tatagatgat ttcatgaggg
    34501 gtggaggtac tataaaagga atggtagacc ttatgaatga atttggtgca gaggttatag
    34561 gtactggagt attcatatct acaacgaatc cttcagaaaa aatggtaaaa gattatattt
    34621 cattgattca attggatgtt aatggagata aaatagtagt agaaccaaac ttaaagactt
    34681 ttaaagatga atatagaaat gaagatttag acgaagaaga agattcagaa tttgaatttg
    34741 agatagatga agattaataa aaaaaatatt tagaaaaata tgtaaaaata aaaagaggat
    34801 atccctagtt gttcatagaa ttatttaaaa aacagtttat attaatttat tccagcgata
    34861 ataattttaa tataaattaa tttctgtcaa aatcaaaggg ggatattttg gtatgaagat
    34921 aactgacgta agagtaagaa aattaacaga agaaggtaag atgaaatgta tagtttcaat
    34981 aactttcgat aatttgtttg tagtgcatga tataaaagtt atagaaggcc ataatgggct
    35041 atttatagca atgcctagca gaaaagtagg cgaaggaaat ttcagagata tagctcatcc
    35101 aataaatgca gaaatgagac aagttttaga agatgcagtt ttacaagcat atcatgaagc
    35161 attagttcaa tgggaagtag ctgctgaata ataaatatat aaaatggaga gagcccgaac
    35221 atttaggctc tttttaaatg tagaatttct attaaaatat gtacttttta gtaaaaaagt
    35281 gctatattat tagtgataat gtatatgttg tatacaaatt gttagataaa tgtattataa
    35341 tgtatattga ttaagagaat aatacgaata aaattaaatt agattgaatg gagtgtatca
    35401 atgaacttta aagctataat ccttgctgct ggcaaaggaa caagaatgaa gtctaaatac
    35461 ccaaaagtta tacataaagt atgtggaaaa gaaatggtta accatattat agatgtttca
    35521 aaaaaatcag gggtaaaaga tactgtcgtg attttaggac atgaagctga ggtagttaaa
    35581 gaaaagcttg cagaagaaat tataatagcc atgcaaacag aacaacttgg gacaggacat
    35641 gctgtaaaga tggctaaaga atatattaat gatgaagata caatagttgt actttgtgga
    35701 gatactccac ttataaaaga agagacactg aagagattat ttgaatatca tatagaaaat
    35761 aaatatcatg ctacagttct tacaacaaga gttggaaatc caacaggtta tggtagaata
    35821 ataagagata agaagggtga ccttcttaaa atagtggaac aaaaagatgc aaattcagaa
    35881 gaaaagatga taagtgagat aaactctgga atttattgtt ttaatggaaa gagtcttaga
    35941 gaagcactag atttgctaaa taataacaat tcacaaggtg aatattattt aactgatact
    36001 gctaaaataa tgagagataa aggattaaaa gttggtgcat ttgcaggttc aactattgaa
    36061 gaacttatgg gcgttaattc aagagtagaa ttatcaaagg cagaagaaat tatgagacga
    36121 agaataaatg aatctcatat ggtaaatgga gtaactataa tagacactaa ctctacctat
    36181 atagaatctg atgttatgat aggcaatgat actataatat atccaggtgt tatgttacaa
    36241 gggaaaacaa ggataggttc agattgtata attggaatga actcatctat aacaaattca
    36301 gaaataggtg atggtacaga aataaaaaat tcaactataa ttgatagtaa ggttggagaa
    36361 aattctaatg ttgggccata tgcatactta agaccaaaga gtgacttagg aaataatgta
    36421 aaaataggcg attttgtaga agtaaaaaat gctattatag aagatggatc aaaagcatct
    36481 cacctttctt atataggaga tgcacatgtc ggtaaaaatg taaatattgg atgtggagta
    36541 gtatttgtaa actatgatgg taaaaataaa tttaaatcag tagtaaaaga caatgcgttt
    36601 ataggttcaa attctaattt agttgcacca gtagttgtag aagaaaaagg atatatagca
    36661 acaggttcaa caataacaca tgatgtccca gatggtgctt tggcaatagc aagagaaaga
    36721 caagttatca aagaaggatg ggtagaaaaa aagaatcaaa aagacgacca aagtaagtaa
    36781 ttatgtagtt tattattttg gctaaaaaat ttagctcgaa attattataa attatattca
    36841 ttagtatttt aaaattttca ggagggttac ataaatgaat actagcggaa gcgagattaa
    36901 aattattgca ggtaattcat cgaaagagtt agcacaaaaa atagctgact atataggtgt
    36961 atcagtacta gattgtgaag taggtacatt tagtgatggt gaaatatgtg taaacatgaa
    37021 tgagacagta agaggttgtg atgtgtttgt agtgcaatct actaacagcc cagtaaatga
    37081 taacttaatg gagttattaa tcttaattga tgcgttaaag agagcatcag caggtagaat
    37141 aacagcagtc attccttact atggatatgc aagacaagac agaaaggcta aggcaagaga
    37201 tccaatcact gctaaattag ttgcaaattt aataactgct gctggagcag acagagtatt
    37261 aacaatggat ttacatgcag ctcaaataca aggatatttt gatataccat tagaccactt
    37321 actaggtgga acaatattag caaattattt taatgaaaag aaaatagaag atttggtagt
    37381 agtatctcct gacttaggaa gtgttactag atcaagaaaa tttgctaata ctttaaatgg
    37441 agaagttcca atagctataa tagataaaag aagaccgaaa gctaatgtat gcgaagttat
    37501 gaacttaata ggtgatgtta aaggtaaaaa tgttatacta ttagacgata tgatagatac
    37561 agcaggaaca atagttaatg ctgcaaatgc acttaaagag tttggagcaa aagatgttta
    37621 tgcttgttgt actcatggtg tgttatcagg tccagctatt gaaagaattg ctaattcaga
    37681 aataagtgag ttaatagttc ttgatactat acaacttcct gaagagaaaa gaatagataa
    37741 gataaagata aaaacagtag ctcctttatt tggagatgct ataagaatga tattctctaa
    37801 tgaatcagta agtaaattat tctaatttat tgtatttatg agagttgttt aaaaggatat
    37861 aaaccttttg agcaactctt ttttgatttt atacttatgg aatgttattt ttttcttgtt
    37921 agaaaggtat atattattgt aaaaagagat tatagtttaa aattatgtat atttaagtaa
    37981 aataaactta ataaagggca tattattcaa aatattatga atataaaaaa tattacaaaa
    38041 aagtattgaa aaaattcaga ttatgtagta ttatgtaaat ataaataaag aaagaggtgt
    38101 ttccaatggg aaggttagaa gatgaacccc taataattaa atgattcagt cacaatctaa
    38161 agtgaatata aaaatctatt gaaagtttat ttataagaat tgaaaatagt atctattcta
    38221 tctttagtgt ttgtgagagg gttctggatt atataagatt actgtaaaga gtaattttgc
    38281 acaataagca tagctgtaaa tgaagagttt cgtttatata atgattgtgg ctgaatcata
    38341 actataatag atagaatgtt tataatagat gattttataa aatactatat tgtaatagct
    38401 tttagctttc aaataaatat tagcaaagga tggaaatgac aatgataaaa ctaaatgata
    38461 atttataaat atctccttac gatatataat aattgtaggg agatgtttct tttttttgta
    38521 gagtataatt tttctagaaa ttctgtttca atatgtaaaa agttggtata tataaatagt
    38581 ataaacagtg ttgctaaaat atggtagata ttatataata taagtggata tgtatataca
    38641 ttatgagtta tataattttg aatttaataa aatagaaacg ttgatttatg ttctgtaatg
    38701 tgggcacctt agagcatatt gagttagtgg tgcaaccggc tatgaaattg tatttattta
    38761 tagatactat cattttcata gcttttttta tttaaaaaat ggttatgtgt tagaaataaa
    38821 tttggttagt acgtttaaat aattttactt agatttttaa ccagatatat tataagtaag
    38881 tattaattaa aaaatttaag ggggaataaa aatgaagtta aaaaagaata aaaaaggttt
    38941 cactttagtg gaattattgg tagtaattgc aattataggt atattagcag tagtggcagt
    39001 tccagcttta tttagtaata taaacaaggc taaggtagca agtgttgagt ctgattatag
    39061 ttcagttaag agtgcagcat tatcttatta ttcagatact aataagatac cagttacacc
    39121 agatggtcaa actggtttaa gtgttttaga gacttatatg gagtctctgc ctgataaagc
    39181 tgatataggt ggaaaatata aattgattaa agttggtaat aaattggtat tacagatagg
    39241 tacaaatgat gaaggagtta cattaacaga agcacaatca gcaaaattat tgagtgatat
    39301 aggtgaaaat aaaatatata caagtgttac agcagataat ttgggaaatc cattaacaag
    39361 taatacaaaa gtagataata aagttctata tatagtactt atagataata ctgtgatgga
    39421 ctcaacaaaa tagttaaaac tatattttta taaaaatatt gtaaatttaa tgaaaaatat
    39481 aatataaaag acaggaagaa aatcttcctg tttttttata ctattttctt taatgttcaa
    39541 ttatgaatga tgatataatt gagatagtaa aggagtgaaa cctgtggcta aaaaagttag
    39601 aataggagac aaactggtcg aaaaaggata tataacagaa gaccagctta aatgggcact
    39661 atcagaacaa aaaaacagtg gaaaaagact aggagaattt ctagtacaag aagggcttat
    39721 agatagtaac ttactaataa gtgtattaaa agaactcttg gatatagaaa gtatattttt
    39781 agaagggaca gaaatagaca ctttagctac aaagatggtt ccagaaaata tatgcaaaag
    39841 atatactgta tttccattta aaattgatgg aaataaaata tgtctagcca tgtcagaccc
    39901 acaagacaga gaagcagttc aagatgtaag gcgtatgtct ggtaaagacg tagagatatt
    39961 tatatcaagt acagaagata taaacaaagc aataggtcat gcttatgcac attcagaaat
    40021 aaataaggca atgactgagt acaacaaaaa tagaactggt ggagtaagag aaacagtaat
    40081 acttgaagaa gatgtaaatg ctgctccaat agtacgatta gtaaataaca tactagaaaa
    40141 tgctgttaga atggaagcaa gtgatataca tatagaacaa agtgaaaatt acatgcgtgt
    40201 taggtttagg atagatggaa tgttaagaga atatatgagg atgaactcag caccatataa
    40261 ggcagtaatc agccgtatca agataatgtc agatataaat atatctgaaa agagaatacc
    40321 acaggatggt agaatctatt taaaagtaga taataaaccc atagatttta gggtttctac
    40381 aatgccaact aacagggatg aaaagatagc tatgagggtt cttgataaga gtaattttat
    40441 ggttagtaaa gaagtactag gaatagacga acatggctct aagatatatg atgaattgat
    40501 aaacactcct tatggtctta tattggttgt tggtcctact ggaagtggga aaaccactac
    40561 attgtattca atgttaaatc aactaaatac agaaaataga aatctattaa caatagaaga
    40621 ccctatagag tatgaattac ctggtgtaaa tcaatctcaa ataaatgaaa aggcagggct
    40681 tactttcgcc agcggactta gagcttttat gcgtcaagac ccagatataa taatggttgg
    40741 agagataaga gatactgaga cagcagaaat agcaattaga gcttctctta caggacattt
    40801 agttttaagt acattacatg caaatacagc agttggagca atttcacgtc ttttagatat
    40861 ggatgtggaa agttttttaa taacttcatc tgttttaggt gtaatatctc aaagacttac
    40921 acgaaaaata tgtgagcatt gtaaggtttc atatgaagca gatattggag aaaaaaaggc
    40981 tcttggtatt gatgtaaatg aatcagtaac tatttataga ggaaaaggtt gtgaaaggtg
    41041 taataatact ggatataaag gacgtctagg tatatttgaa atgcttgaaa ttactccaga
    41101 aataaaagag ttaatagatt catctgcaaa tcaaagagaa attttaaaga tggctagaaa
    41161 acaaggcatg gttagcttaa aagaggatat agttaaaaag gttttaaatg gaaagacaac
    41221 agtagaagaa atgattagaa taattttgat gactgattaa aggatgatat tatgaaaagt
    41281 tttaaataca cagtaataaa agaggacgga aaaaagcaaa ctgatgtgat tgaagccaac
    41341 gattttaatg aagctagaaa tcttcttaga aagagaaatc ttagagttat tgaaatcaaa
    41401 gaaagcaaaa ataaaaatat aagattatct agtagaaaga gaaaaaaaga cttgggagct
    41461 gaccagataa gccacttttg tagacagttt gctattatag tatcttctgg tataaatagt
    41521 atttcaggat tagaaacatt agctagaagg tcaactaaca ttacattaag agaagaaatt
    41581 aatcgtatag tggcagaaat aaaagtaggt tctactattg cagattcaat gctttcatca
    41641 aaatcaaagt ttccaaagtt acttggtgct atggtagcta caggtgaagc tacaggtaaa
    41701 ttagatgaag tattaaaaag tatggcttca ttttatgcaa gtgaacacag ggttaaacaa
    41761 aagcttagaa atgctgcaac atatccatta atagttttga tttcttcatt tataatgatt
    41821 tttatattta caacatttat ggtgcctaag atgattaatt caattacaac agtaggagca
    41881 actcttccac ttataacaag aattgttatg gggtttggta tgtttatgaa gaagttttgg
    41941 ataatagtac ttttagttat tatattattt atctatcagt ttaaaaaata tttaaaaacg
    42001 tcagttggaa gggctcataa agatagagtt ataaacaaga tacctgtttt aggaaaagga
    42061 ataaattgta tggtagctac acgattttca agagcattgt atctatttgt atcaacagga
    42121 tacccattag ttcaagggct tgattatatt atagatagtg taaataacac catggcagag
    42181 aagattttag catcagctaa agatggaata acaagaggag aaggcttagc agaaaattta
    42241 gagagatata cgtattttga ctctgtgttg gtacagatga tagctatagg ggagcagaca
    42301 ggggaattag agaatataag tagacagatg gcagaatttt atgagtatga atccgagatt
    42361 tatttaaata ggatggcctc aatgatagag cctgttttaa taattgcagt tggtattata
    42421 gttgcgatac tggttgtatc aatatttatg ccaatgctta gtatatatga tgccatgtag
    42481 gagggaaagg acaaatgaat aaggtttatg tatcatatta tggcgattct atttccatag
    42541 ttgagggcag atataaacac gataaggata agttttatgt aaaaaatttt aatgtgtttt
    42601 caatagagga tattgcacaa gatttttcta aggaaaagta tgctctattg agatacgcat
    42661 tagaaaatgt taagttaaaa tcaagacatg tagttttttg tttaaataca agagatgtaa
    42721 ttttaaaacc ccaaaaactt cctaatatgg acaaaaagga tttagatgga tttatgaagc
    42781 tagagatgga cgaaatgatg gctttggagt cagatgaata tgtattttcg tatgaagtat
    42841 ctagtgaaac acatgataat tcagatggcg atgaatcaag cttaaatctt atcattggag
    42901 ctatacaaaa ggaagaggta aatgcaattg tagagataat gcatgaattt gatttagtat
    42961 tagatagaat agatacatta tcaacagctt acttaagaat gcttaaaaat ttagactaca
    43021 atgatataat ggtaaccaat ataagtgaca atagtacaat tataaatata tataagaaag
    43081 atactttatt tattagtgat aatataccta taaagataac tgctaaagat atggacatgc
    43141 aattattaaa tgtagtagaa gaatcaaaag gtcttatgaa ttactattcg tcaagaaact
    43201 ttggtaaggt tacggatact atattaatat taggaaaaag atattccaat aaattaattt
    43261 atgaaacttt tagctctgca ttttcaagct atgtttctca aggccttact gagataatgg
    43321 atatatctga tatgataact ggagatatag atgaagatga tataaattca attgtagagc
    43381 ttttaggaag tatgatagaa cctaaaggga aaagagattt tgaaaatata aactttttac
    43441 caatggatat acttagaaaa cagataaaag ctaaacaaat gaaaaacata ctgaaaattg
    43501 ctccaatagt tattttgatt cttgctatac cttatttatg tttaattttt tcaaataatt
    43561 tagcaaataa ggaacttgaa aatgttaatg gtgaaataag aaatattgaa tctgcatatt
    43621 atcagattgg aaatatagaa aaaatgatac agagtaaaag cgaagaaata aaggtatatg
    43681 atatgttaat tgggaaaaag gtaaagtggg aaaatttatt ggatgatata gataaaaata
    43741 ctccaagtaa agttgaacta acaagtttat caacaactta tcaaaatctt ggaactaata
    43801 ataaagctga taattcaaaa agtaataaga ctacaacaga taaatcaagt aacaatgaaa
    43861 caaaatcaag tacgaaaagt gatagtaatg gagataaaac agataatgat ttaaatgaag
    43921 ataagactac aaatgtgtca gaagcattaa ctggaaatag tgagactaat agtaataaca
    43981 cggataaaga tgataaaact ccattgtatg ataagatacc aaatgttata aatatagaag
    44041 gaaatgctaa agattcctct tatgtaggtc aatttttata taaattaaag ggattatact
    44101 atttcaagga tgttaaatta catagcataa aaagtaatgc agaagattct aactatacat
    44161 ttagtatgac attatacctg aaagaaggtg tattaactaa tgaataaaga tatatttaaa
    44221 aaagatataa aagatatatt taaaatggaa gttagtctaa aagggattct tataaaggtt
    44281 ataattttat tagctatttt atcatatggt tattttggac tttaccctca atatcagaaa
    44341 tatattgcta caaaaaattc tgtaaaacag gctactgaaa aattaaatat atataaagag
    44401 aaaactgcac ttatgccaaa atatgaaaaa caacttgaag aagttgaaag tgaattaaaa
    44461 gaaaaaagca aaaatctttt atatgatatg caagatggtc tttttttaat aggtttagat
    44521 aaaaaaatga aggcttataa tattgactta actagttatg acgttggaaa tgttaaagaa
    44581 tacgaacatt tttatggtat atcaacaaca ataagtgtta gaggtgatta tagaaatgtc
    44641 aaaaaattaa tggcttattt agaagaacaa aaaaatgtta ctcaaatact agattataca
    44701 atgacttcat atatagaacc agaaaaagaa gaggaagaaa caacaaacaa taaggattta
    44761 attaaaaatg tgaacataaa taaagataca aaaatatact gggtggaagg cgaaaataag
    44821 tggcatttat ataaggattg tccattgata aaagaaggag agattctaaa aaatgacaaa
    44881 cttttagata ggtctactaa ttatctatgt aatacttgtg tacttagagc tgcaacagaa
    44941 aaagaagcaa aaaaagaagt cgtagctcca aaggcagaag gtgtagtaga tgctacattt
    45001 aaatttataa tgtacactaa agagaatact acaatgatac ttgatacaga taatccatct
    45061 tcatggagac caggaaaata taatccattt aagtctagtg ctaaataaag ctaagtaagc
    45121 tttaaagata ggtgatgagt ttgtacaaaa ataatgaaaa aggtcttact ttattagaag
    45181 taataatagc tgtttttata ctgacaatag ttttaagtat ttcttataaa gtgttcaatg
    45241 gtataacatc agcagtaaaa aagcaacaga ttattacaga tgctcaagta aatattaatc
    45301 taattaataa gtatctaaat agagatttgg aaaactgtaa agagctaact aaaactggtt
    45361 caggtaataa ttatgaatac aatatagaga tgccagataa tgttgtaaaa tatgaagttt
    45421 ctatagaaac taaaaaaaat acagaggtat attctgtaac gagaatccaa aacaatacaa
    45481 ttgatacaga aaatgaagtt agagaagaga taatctataa tcaaccacta gttcaaaaca
    45541 ataaagaaat gaaggaaaca ccatttaaaa tagaaaagca aactggtaaa tctatttata
    45601 ctgtaagtat atactataat gaatcagtgc aagaaagtca taaaaatagc aatttaaata
    45661 acaaaactta tacatttgat gttatgtcaa gaatagggta ataagaattt attaaaaaat
    45721 aagtaggttg ataaaatatg agtaaaaaga atagtgaaag aggattttcc ttaattgaag
    45781 tgttagtagc tatggctatt atgggaattg tactatttgc attttttaat attatcaata
    45841 ctaataacaa agcaaacact aaaaatgaca cagatataac ttccttaaac tatgtccaaa
    45901 gtgaaataga aaatctaaga gaaaagataa aaagtggaga atttgatttt gatagtttag
    45961 ataaactaga agatggaact gtcgtatatg aaaaattaat agataaatca aaaaaagttg
    46021 tatatgataa agttcttagt gaaggtgacg tgagcttata tgatactcca tatgaaaaga
    46081 ttacaacaat aaaagatgaa gatggtaatt taatcgacaa aggaaatatt acaaataaga
    46141 taaagactat tgtagaagat aaaagtggtc agatatataa aatagctgta actgggaaaa
    46201 gcatgaatga ctattcaagt aaaaaagagg ttaaaattgt aactgaaata tttaaagata
    46261 aataatttta cttgggggtg agattttgag gaagtggaat aaatttaaaa gtgaaagagg
    46321 ggcagcttta gttttagttt tgattgtagt agcattgctt tctattgttg gattgatatt
    46381 ttcaaatcag atagctaata gaataaaatc tacaaagact actaatgaag gtatacaagc
    46441 aaagtattta gcagagacat gtgtggaaaa tagtattgat aaagcatatg aaaaattgta
    46501 tgatgagctt gagaaaatgg ataatgagtt taaaagtgaa aatcaagaaa aatccatatc
    46561 taggtcaaaa ttaagaaata tatcagatga agattttaat aatcaagatg agaaaaatat
    46621 tgaagcagaa agacttggat atatgaataa tataaatttc tatttaaata aagcttcttc
    46681 agacttggaa aaagctagta tggaattgaa aaagctatat gatttagata tgttggacta
    46741 tagagacatt gaatatgtag atgcaaatat tatttcacat agagattcta tcttagaaat
    46801 ttgcaagaat tatacttctg gagatattag taaaataaat gaatatattc tgaaagaaga
    46861 tatagactca actacattga ttgaggcaaa gttagtgaat aatgatattc ttttgaaaat
    46921 gtttttagaa gaaaataaaa ttgaaaatga acatttaaat tcagcctttt cacatactta
    46981 taaggcatta gataacattt ctttggcgat gcaaaatatg attgagtata gacatacgtt
    47041 tcatatagat gagccaaaag tagaagtatc taatgggatt ccagattctc aacaatatta
    47101 tgaactaata caaaatccta taataaatag tatggagtat atctggaata gtaaatggga
    47161 tacattagaa aacctattgg aaattttacc aaatcaaact caaggattta attctttaag
    47221 agttcatttg agaaataatg taagaaaatt tgagaagtta agcgataata tatctagtgg
    47281 taaaaaaaat acagcaaaaa attttttaaa gtataaagag ttattgtatg aaatatcaga
    47341 ccaatgtaat caactaaaaa gtatgtctta tgagaaaata cctgttaaat atgataatat
    47401 ggctttgata acaacttttg actatataca aaatgagctt ttagcagaga taaaatgcag
    47461 attaaaagaa ttaaaaccac aagaaattga taaaacagaa ggtattacta taaaaatacc
    47521 tttttataag gctgactacg acatgacaaa agaaggatgg cctaaattaa aagaaaatgg
    47581 ttcaggggcg gagttaagct taatggtaac tggtgataaa gatggaataa aagaagtaga
    47641 agttacagat ggtaaaaaaa atattattgg tttaggtgtt gaagaaaatt caaattcaaa
    47701 gtataaggtt gacgccattg taaactttaa tctaaatata gatacaaatg tagttggaaa
    47761 ttatgatata aaagataaaa ttttgattaa tcatgatata agttcataca aaaaagtaaa
    47821 ctaaatataa gaagcaactt agtataaata aataataaaa taattttatt atttactact
    47881 aaaaaaataa gtaaactaat agaagatatg gagagtaaat attatgtata tttatgattt
    47941 attagagcaa ggtataagac taaacgcatc agatatacac ataacagttg gaacaaatcc
    48001 tgtagctaga gtaaaaggtg gatttgtaaa actaagtgaa caaatattga catcagaagt
    48061 aacaatgcaa atggcaaaag acatagcggg ggaatctatt tttaaagtaa tagaagaaca
    48121 tggagaagct gatttttcag cttctctaaa aacaggagaa agatttaggg taaatgcata
    48181 taggcaaaaa ggaaattacg caatagcaat aaggactata acagcagaaa ttccaacatt
    48241 tgaaaaatta ggccttccag agagtataaa atcttttact gaaaagcata aaggattagt
    48301 tttagttaca ggtccaacag gaagtggtaa aagtacaaca cttgcaagta tgataaatat
    48361 aataaatgaa aaacaacaaa aacatataat tacacttgaa gacccgatag aatatgtaca
    48421 tcatcataaa caaagtttag taaatcaaag agaagtagga actgatacag aaagttttca
    48481 ttcagccctt agagctattt tgcgtcagga cccagatgta atactaatag gagagatgag
    48541 agaccctgaa actgtttcaa tagcattaac agcagcagaa acaggtcatt tagtattttc
    48601 aacactacat acagtagggg cagctaagac aattgataga atagtagaca tgtttcaacc
    48661 atcccaacag caacaaataa aaacacagtt atctacagtt tgtgaaggtg tggtatcaca
    48721 gcagttactt cctacagcag atgggaaagg cagaatagca gcaattgaat tgatgtttgc
    48781 tactccagca ataaaaaact tgataaggga aggcaaaaca tatcaaattc caaacatgat
    48841 acaaactgga gttaaagtag gtatgaaaac tatggaccaa gatttaatgg aactttataa
    48901 aaatggaaag attacaaaag atatggcact tagtaggtgt actgaccaag agtttatgac
    48961 aagaatgata ggtggagtaa actacaatgg atattataat cgttaatcta tatgtattta
    49021 tagtgggtat agtgtttgga agtttcttta acgtctgtat ttttaggatt ccagaaggta
    49081 tatctatttc tagacctcct tcccattgta tgagttgtaa tactagacta aagccaatag
    49141 acttaatacc agtgctaagc tatttgatga gtggcagaaa gtgtagatat tgttatgaga
    49201 aaatttctag tagatatgct atagtggaat taattacagg aattttattt ttaacagtat
    49261 ttatgttata tggaatatct acatcaacta tttattattt ggttcttgtg tctttactga
    49321 ttataattac atttatagat attgaccact ttataatacc agataaaata ttgatttttg
    49381 gagctatatt ttctatgatt tttaaccttt tatttaaaga aattccagtt aaggattcaa
    49441 ttctaggtgt ttttatttgt ggaggaagtg tctggattat agttcttttg attgaatttg
    49501 taataaaaaa agagtgtatg ggtggaggag atatcaaact atttgcaatg ctaggccttt
    49561 acatgggtgt taaaaatggt cttttgacag ccttactaag cgtttatgta ggagcagtct
    49621 atggaatctg tgtaataatt ataagtagaa taaaaggaaa ggaatataat tctgttatac
    49681 catatggacc ttttatatct attggagcat taataacaat cttatgtgga aagcaattac
    49741 ttgaacttta tttttctatg gttatataga tgatagtcaa gttaaataaa gttttaattt
    49801 aaaaaaatga attaaagtat ttaataagga caatattatt attaacccta ttactaaagt
    49861 gctacaaact atggagtata taataataat ttccttattt tttgcacatt tgataaataa
    49921 atctctatgt gttttttgtg atagagaaaa gaaaaattta tataatacgt tttttattta
    49981 cataataact gtagttttat ctgtattaat atatctaaaa tttgggatta gtgtagaatg
    50041 tgtacaatat atggttttaa ttccattttt aataattata tccattgtag attactacac
    50101 aatatatgta tatgatataa caatagttag tggtataata gttcaaggta taattttttt
    50161 ggcctttttc aatatagctc aatttgatta tataaatcat atatttggac tattgatagg
    50221 ctttattata ccttatatta ttgctaaact aacaaaagga ttaggctatg gagatgtagg
    50281 tctctatagc ttatgttgct ttgcattggg aaataattat gggttttatg tgatagtttt
    50341 atcatttatt ttagcgtttt tgttttttat tattttatac ataactaaaa tatttaaaga
    50401 tgtagatata agaaagcaaa ttccttttac accttttatt tccttgtcaa caattttaat
    50461 aatatttaca gagtataata tatttaattt ttattataat ttgttataca aatttatata
    50521 acaggaggta agaaatgtac gtagtagtag ggttaggtaa tccaggaaag aagtatgaga
    50581 agactagaca taacgttgga tttgatgtta tagatattct tgctaaagaa tacaatatta
    50641 gtgttactaa aataaagcat aaagctttga ttggtgaagg gagagtaggt actgaaaaag
    50701 tattattagt taaaccacaa acttatatga atttaagtgg agaaacatta atagatatat
    50761 ataaatatta taaggttgat ttaagtaata tagtagtagt atatgatgat atagatttag
    50821 aagttggaaa gatacgtata agaaaaaaag gaagtggagg aactcataat ggcatgaaat
    50881 ctataactaa gtgcctaggt tcaaatgact ttccaagagt gagagtaggt gtatctaaac
    50941 cagaagctgg tcaagactta gcagactttg tactttctag atttagaaaa gaagaatctg
    51001 ataacataaa tgaagcatta gaaaaagcgg cagatgctat tgactcaata ataagagaaa
    51061 atatagatat gtctatgaac aaatataatg gatagtgaga gggagattta aatgaatgat
    51121 gtttttttat atcctttgca aaattcaaaa gagtataaag atataataaa ctgtataaaa
    51181 aatacaaaag gctcattatt ggttaatgga cttttaccag tacaaaaacc tcatatatcg
    51241 tattctatat ttaatgattt atcacgacaa atgattttta taacgagtag tgatttagaa
    51301 gcaaagaaag tatacgaaga tttaagtttt tatatggaag ataaagttga atatttaggt
    51361 tttcaagata tttattttta tcacttggat gcaaaggaca gaaacgaaga agcaaagaaa
    51421 ttaaaagtat tgttaaaact agcaaataaa gaaaaaatca ttttagtaac ttctattgag
    51481 gcagttttaa gaaaatacat accaaaacaa gttttgctcg atagtgtatc tcattataag
    51541 gtgggagata gcttagactt agaaaagtta actgagaaat tagtttcatt gggatatgaa
    51601 agagtttcaa aaatagaggg gtttggtcaa tttagtataa gaggtggaat tattgatgta
    51661 ttttcacttg aatatacaaa tccaattcgt atggaattat ttgatgatga gatagattcc
    51721 atacgaactt ttgacgtata ttcacaaaaa tcaattgata aattgcaaca attctctata
    51781 actccatcta gagaatttat ttatcccgaa aaaactacag atgcattagt taaattaaaa
    51841 aaagaaacaa ctaaaaatac tgatgaaggt acatttcaaa atatagatta tatatcaagt
    51901 aagacttatt ttgaaggtgc agagaactat atagattata tttatccaga agaaaacaaa
    51961 agtatattta cttatttagc agatgatgca atagtattta ttaatgatat aacgagactt
    52021 aaagaaagat gcgaaaatta tataaatgag tttagagaaa attataaatt aaatcttgaa
    52081 agaggtctgg ctattaaaaa ccaaggtaaa ttgttatatc actatacaga tttagagtac
    52141 ttagtaaaag acaagtctgt ggtattaaac tcgctattgc caaagtctat aaataacttt
    52201 tctataaaat ctataataaa ttttgaaagt agagaagttc ctacatttaa tggaaaggta
    52261 gatttgcttg tagaagaatt aaatcggctg aaatataatg gatacaaaat aattttagca
    52321 acaaatacct tagaaagagc aaataaatta ggaaaagatt tattggacaa aggcttagaa
    52381 acgaccattt ctaaagatag agatattgaa attaaatctt cacaagttat aattgtacct
    52441 gcacacataa acagtggttt tcagtataaa tctataaagt ttgttgttat aacagataac
    52501 gaaatgatag gtgtttataa aagagcgtct aagactagca ataaaaaagt taaaaaagga
    52561 aagaaaatag aatccttttt agatttaagt gttggagact atgtagttca tgaaaatagt
    52621 ggtgtaggta gatacacagg gattgaacaa attacagtca atgctattaa aaaagattat
    52681 atgaaaatag tatatcaagg tggagataat ctatatgtgc caatagacca gatggacaaa
    52741 gtacaaaaat atattggtgc agaagtagaa aaagttaagt taaataagct tggaacaaat
    52801 gagtggacga aagcaaaagc aaaagttaaa aaagaaattg aagatatgac aaaagacttg
    52861 attgagcttt atgcaaaacg tgaaaaaata caagggtata agttttcaaa agatacacct
    52921 tggcaggcag agtttgaatc gttgtttcca tatcaagaaa cagaagacca attaaaggct
    52981 atagaagaaa ctaaaaaaga tatggaatca agtaaggtaa tggataggct agtatgtgga
    53041 gatgttggtt atggaaaaac agaggtagct attagaagta tttttaaagc ttgtatggac
    53101 caaaaacaag ttgctgtatt ggttccaaca acaatattgg cccaacaaca ttataataca
    53161 ttcaaagaga ggtttgaaaa ttatcctttg agagtagaag ttttaagtag gtttaaaaca
    53221 ccaaaacaac aaaaacagat tattgaagat gctaaaaaag gattagtaga tattttaatt
    53281 ggaacacata gaataatatc caaagatata aatttaccaa acttaggtct tgtagtcatt
    53341 gatgaagaac aaagatttgg agtaaaacat aaagaagctt taaagaaaat taaatctaca
    53401 gtagatgtac ttacactttc agcaactcct ataccaagaa cattacatat gtctttaagt
    53461 ggaataagag acatgagtgt tatagaagaa cctccacaag aaagacatcc tgtaataaca
    53521 tatgttacag agagtaagga aagcgtaatt caagatgaga tagagagaga attaagtaga
    53581 ggtggacagg tattttttgt atacaataga gttgaacaca ttgaagaaat ggcaagtatg
    53641 attcaaaaac tcgtaccaga tgctagagtg gctgttgcac atggaagaat gacttctaaa
    53701 tcattagaaa atataatcct aggattttta aataaagatt atgatgtact agtctgtact
    53761 acaataattg aaactggtat ggacatatca aatgcaaata caatgattat atatgatgca
    53821 gataaaatgg gattggctca actttaccaa ttgagaggta gggttggaag aagttcaaga
    53881 caaggatatg catatctttt gtatgaaaaa gataaaactt taagtgagat agcggagaag
    53941 agattaaaag ctatcagaga atttacagag tttggttctg gttttaaaat agcaatgaga
    54001 gacctcgaaa taagaggagc aggaaatatt ttaggttctc aacaacatgg tcatatggca
    54061 gttataggtt atgatttgta cgttaaaatg cttaatgatg caattaaaaa agtcaaaggt
    54121 gaacctattg tggaggaaat tgatgttgaa atagatttaa gtgtaaatgc atacattcca
    54181 gataattata tcaaagatga gttgattaaa attgaaatgt ataagaaaat agcttctatt
    54241 gaaaacaaag aagacatgtt ggatatacaa gaagaacttg aggatagatt ctctgatata
    54301 cctaaaccag tccagacact tcttacaata gcttatataa aatcgttatg taagatatta
    54361 aaaatagaaa agataagaca attaaaagat gaaatattat tagttccaat aacaaagtat
    54421 agaactaaac agaaaatagg ttataatata gttacagaat tagaagaatt attagaaaag
    54481 atgtgcaagg taaaataact tgtaaattta agaagggatg ttttaaattt gaaaaaagta
    54541 ataacattgg taatagctat gattttggta gtatctgtga ctgcttgcag ttctagtaaa
    54601 ggagaaactg tggcaacagt tgaaggtaca aagatatcat cagatgaatt taaaaaaact
    54661 atagctcttt ataaagattc tatggaacaa acttatggaa aagatatatg ggataaggaa
    54721 gttgaaaagg gtgtaaaata caaggacaag tttaaagatt taattcttga ccaacttata
    54781 actacagaag taatatattc tcaagctaaa aaagataact tacttcctaa aaaagaggat
    54841 gttgaaaaaa gttttaaaga attaaaagac gctatgggta aagatgaaaa atataaagaa
    54901 caacttaaga aattaggtat agatgatgag tttttaagag accaacaaga gaaagattta
    54961 gcaatgcaaa actatcaaag taactttgct aaaaagacta aaatatcaga tgaagaaatg
    55021 aaaaaatact atgatacaca taaagatgaa tttaaaaaag atgaggtaga agcttctcat
    55081 attttattga aaacagtaga tgataataac aagccacttt cagataagga aaaagctgaa
    55141 gctaagaaaa aggctgaaga ggctcttaaa gaagttaaat caggtgagga ttttgcaaaa
    55201 gtagcaaaaa aatattcaca agatacttca gcaagtgatg gtggtaaatt aggattcttt
    55261 tcaagggggc aaatggttgc tgaatttgaa gatgctgctt tttctatgaa aaagggtgaa
    55321 gtatctgatt tagttgaaac tcaatatgga taccacataa ttaaagtgac agacagaata
    55381 aatgagcaaa catcatttga agatgctaaa gaaactataa aagaccaact gttgaaaaat
    55441 aaatatcaag aacaaataga aaaattaact aaagaagcta aggtagaaaa agatgaaaaa
    55501 gtaataaata aaatcacaat ctaagactta aaaaaagagt aatatgctta aaaaagctat
    55561 atctggataa gatatagctt tttttgtata tttttcttaa caatggtaaa aataaactta
    55621 aagtaattta tggagggatt aaaaaatatg aaagcaacag gtatagttag aagaatagat
    55681 gatcttggaa gggtagttat cccaaaagag ataagaaaga cattaagaat tagagaagga
    55741 gaccctttag agatattcac agcaaaagat ggagaagtca tacttaaaaa atactctcca
    55801 ataggtgaat taaatgaatt ttcgcaagaa tatgctgaaa cattagctga agtactagga
    55861 tatggagtgt tgataacaga cttagattct ataatagctg tgtctaagct tcctaaaaaa
    55921 gattataaag aaaaaagtat aagtgatgag ttagaagcaa taataagtga aagaacagta
    55981 aaatattcaa aagataaaaa cattttacca ttattcaagg aagaccaaaa agaatatact
    56041 agtcaagtta tcatgcctat aattagtgca tctggtgact gtataggttc aattgtagtt
    56101 gtttcaaagg ataaagatac aattgcagaa agtgaagaaa aatctttaaa aattgctgct
    56161 aactttttag gaaaacaagt tcaataattt tatcataaag accttttaca tgaaggtctt
    56221 ttgaagtttt tgtgtaaaat attgaatata gcattaaaaa tatggtatat taaagtttgt
    56281 tatataaaca gtatggaggt tatgttatga acaataacaa aaataaagac tcctttctaa
    56341 aaggagccct tatacttggg ctagcaggtg taatcgtaaa aataatgggt ggatttttta
    56401 ggattcccct tggaaacatg attggttcag aaggaatggg atactatcag gctgcttatc
    56461 ctgtgtatac tctattttta acattagcta ctgctggatt tccaacagct gtggcaaaat
    56521 tggtttcgga aaaagttgca attggaaatt ttaaaggtgc aaataagata tttaaggtat
    56581 cacatacagt tttattcatt accggtataa tatcattttg tatattattt tttggagccg
    56641 actacatagt aacaaacgta atgaaaaatc caggtgcgtt atactctatg aaagccattg
    56701 ctccagcatt actatttgtt cctgcaatgt ctgcatatag aggatatttt caagggagac
    56761 aagatatgac taagattgct gtgtctcaag ttgcagagca attttttaga gttgtattag
    56821 gtcttacttt ggcctacttg cttatgaaga gtctaggtca gacttttggt gcagcaggtg
    56881 ctatatcagg ggctacaata ggttcaatag catctatgct ttatttggtg tttgcttata
    56941 tgctagggag aaaagagcgt agagcagaga tagatgcaag ccaaagattt aaagatgaaa
    57001 gagtgtctta tatttttaaa aagcttttaa ctgttgccat tcctataaca ataggagcat
    57061 cagtaatgcc acttgtaaat atgatagata atgttattgt aataagaaga cttatggaag
    57121 caggatttac atacaaagtg gcaaattcaa tgtttggtca attaacaggt atggcaatgg
    57181 ccacaataaa tttaccagca gtcataacaa ctgcaatgag tatgagctta gttccagcaa
    57241 tttctaaagc atatgcatta ggaaataagt caaaagctag aaaagatact aagagtgcag
    57301 ttaaggtaac tttacttata gtattgcctt gtgcgtttgg tatggcttct ttagcaatac
    57361 caataatggg tcttttattt ccacatgaac catcttctgt aggaactatt ttgtttactc
    57421 ttactccatg tgtattattt ttaggattaa tacagacatt gactggtata attcagggaa
    57481 tgggaaaacc aatagtacct gtaattgctt tatgtgttgg tatgctatgt aaaattgtaa
    57541 taagttatac tttaacaggt ataccagata ttaatgtact gggttcagca tttggtacag
    57601 ttacagcata ctttgtggca gccatgatta acttactata tgttaaaaaa cacatgaatg
    57661 taaacttttc taaaaaagaa tttataataa agccatttat aacagttatg acaatgttta
    57721 taatggttaa gttgagttat ggtgctttag ttggattctt aggaaacagc atatctacaa
    57781 taattgcaat atgtgttggt ggaattgtat atgtagtagt aatacttgga ataggtggaa
    57841 ttaaaaaaga agagattcta actatgccaa aaggtgataa attatataaa ttgttaaaaa
    57901 aagttaaact tataagataa tataggaata tatatgcaaa taaaggaaat actatacaaa
    57961 tagtaaatct ccttatttgt ataataatat aaaaataaag tgaaatttgc taataggagt
    58021 gatgttatgg gtaagataag tattgtaggt cttggaccag gagactattc tcttataagc
    58081 caaggtgtgt tagaatcttt aataaatagc cctaaagttt tttttagaac agagaaacat
    58141 ccaataattg ataaacttaa agaaactata caatacactt ctttagacta cttttatgaa
    58201 aaagaggaaa attttgataa tgtttatttg aaaatatctg aatttatcat agaagaatca
    58261 gcaaagggtg acctagtgta tgctgttcct ggtcatccaa gagttgcaga gaagactgta
    58321 agtataatag agagattagc caatgaaaag cacatagcag tagaaatatt gccttctatg
    58381 agctttgtag acgctatgtt taactatttg gctatagacc catctgaggg atttaaactg
    58441 gtagatgctt ttgaaataga aaattcatat atagacttgg atacaagcat gataataact
    58501 caggtatatg ataaatttat agcatctaat gtaaagttaa aacttatgga acattatgac
    58561 tataatcaag aagtatgtat agtaaatgga gcaggtgtca aagatttaga aagtaaaaag
    58621 tttataaagc tttgtgaatt agacagaaat gaaaactttt ttgactattt aactagctta
    58681 tatataccca aaagttctaa aaagatgtat aatacagtac atgacttaga aataatagtt
    58741 aatacactta gaagtccatc tggatgtgaa tgggataaaa aacaaacaca tcaatcatta
    58801 aaaaattctg ttatagagga agcatatgaa ctttgtaatg caattgataa taatgatata
    58861 gatgaaatgg tagaagagtt aggtgatgtt cttttacagg ttatattcca ttgtcagata
    58921 ggaaatgagg agggctactt tgatttaaaa gaagtagtaa atggcatatg taaaaaatta
    58981 attcatagac atcctcatat atttagtggt gcaaaattag atatgtctaa gtttgagaaa
    59041 acttgggaag aattaaagaa agaagagaaa ggcgaaagta ctataacaga tggccttaga
    59101 aggataccaa aacatttacc agctcttatg aaggctagta aagttcaaca taaagcagca
    59161 cttgtcggct ttgattggga caatgtagaa gatgtattta aaaaaattga agaagaatat
    59221 caggaattac ttgacgaaca cagggtcggg aatataaaat acataaagga agagctaggc
    59281 gatttattat tttcgatagt aaatctagct agatttttag acatagactc aggagaagcc
    59341 ttgaactgta ctacagaaaa attcataaat agatttgact ttatagaaaa aagtgcaatg
    59401 aacttgaata aaaaattaga agacatgaca cttgaagaga tggatgagtt ttggaatcag
    59461 gctaaaaaac aataaaattg tggaaggaaa tttgtcaaaa atctagaact tttatcacaa
    59521 agatagaagt ctatattata aacattttta ggaggtaaat atcgtgaata aagctgaatt
    59581 agtatcaaag atggcagaaa aaagtggatt aacaaagaag gaagcagaag ctgcgttaaa
    59641 cgcatttatg agttctgttc aagatgcact agtaaataat gaaaaagttc aattagttgg
    59701 atttggaaca tttgagacaa gagaaagagc tgctagacaa ggaagaaatc caagagatcc
    59761 agagcaagtt atagatatac cagcttctaa agcaccagtt ttcaaagctg gaaaaggatt
    59821 aaaggatata ataaatggat aattagaaat cttgtgaaaa agtgtggata aatttgccac
    59881 actttttcta tagaaccaag gaaggtgata attatgagat tagataaatt tttaaaagta
    59941 tctaggatta taaaaagaag aactgttgct aaagatgcat gtgataaagg gattgtcact
    60001 ataaatggaa aagttgctaa atcttcttca gaggtgaata ttggagatac attagaaata
    60061 caatttggag agaagaagat gaagtttaag ataaatgaag taaaagagca tgtattaaaa
    60121 aatgatgcaa aagaaatgta cgaaatttta gaataaaatt aatagtcctc tagtatatta
    60181 atagtagtat tattgaaata tttactgggg ggatattatg gaacagaaca taactttgaa
    60241 agatagatca aagctggtta tttcgggagt cgagcacata tactctttta atgacaaaag
    60301 agtagagctc aaaacttctg taggcgagat ggtaattgaa ggcgaaaacc tagatatgag
    60361 caagctaagt atagacgaaa atataattag catagatgga actataaatt ctatggtata
    60421 tgcaaagcct aaaaagccac aagagagttt cttgaaaaag gtatttagat agatgatacc
    60481 ttttactcaa gatgtaagca ttttttatgc tactatttat ggtggaatac tcataggggt
    60541 gttgtttgat ttttatagag ggctaagagg gaattttaaa ttcatcaatt attttgctat
    60601 aatctttgat gtattgtttt ggtttctagc tacggttata atattcgtaa caataaacct
    60661 tacagaattt tttgatttaa gatattatca ttttgtggct ttgtttattg gttttatttt
    60721 atactataac accataagta aaattgtttt atcaattatc aataaaataa ttcgttttgt
    60781 gagaaattct tttaaaaaag ttacacatta catagtcagt tttttaaata atttgtatta
    60841 cgttataatc tattcactac acctactatt tgatattata ttttatatac caaacatatt
    60901 tatagcaaca agaaaaagta taaaaagaaa atcaaataaa aaattaaaga acaagaaaaa
    60961 atcaaaacct aagaagaaaa aaaataaaac taaaaaaagg gtgtaggaaa aatgaactta
    61021 agaaaaaaat tttcaggaca gattattgtt atcagtttat ttttaggaat atcaattttt
    61081 agtatgatga caggatttgt atttgagtat acaaaagcta aggaatataa aaaagaaata
    61141 gcaagtctaa ataaacaatt aaaaaagact gaaatacaaa taaacagctt aaagaaagat
    61201 gaaaaatcat atgaaggaga cttagaggat atagcaagaa aaagattgaa tatggtaaaa
    61261 ccaaatgaaa cagtttatgt agacataaat cgttgattaa aacttgctaa taagtttaca
    61321 gatgtattga ttttaaaatt taagatttaa taaaaaagtc attcagttaa ggatggcttt
    61381 ttgtttttat tgaggaggga atttcataat gaaagtagga gctatagata ttgggacaaa
    61441 ctcaatgaga ttactgatag cagattatag agatgggaat tttataaaca gaaaaaaatt
    61501 tgttaataca actagaatcg gttatggtgt ggatagtaaa ggatatataa aagaagatgc
    61561 tatcaaaaga aatataaaag cattaaaaga attttctgat aagtgtaatg atgaaaagtg
    61621 tgaaaaaatt tattgtatgg ggacatctgc tcttagagac agtaaaaatg gagattactt
    61681 tgttaaatta gctaaagaag aaactggaat agatgttgat atagttacgg gaatagaaga
    61741 atcaaatttg ggctttaagg gtgttttaga aggaatacaa ggtgatgata ctattattgt
    61801 tatagatatt ggaggaggtt caacagaatt tattgtaggt gattcagaag gaattaaatt
    61861 taataaaagt gagaatgtag gtgctcttag gatgacagag aggtttttga agcacgatat
    61921 tattgaagat gaagagtttg aagctatgag ttcatttata tatgatgaga ttgacaaaac
    61981 gttaaatcat ataaaagaca gaggattaaa aactcttata ggtataggag gtacgattac
    62041 atcattatca gcaatgaatc aagaattaga gatttactct atggaaaaaa tacataatag
    62101 taaaatacac aaaaaagaaa tagaagaaat tctacaaaaa ttaataaaga tgacattaag
    62161 tgataaaaag aacttaaaag ggctacaaga aaaacgtgcg gatattataa ctgctggtgt
    62221 aaaaatattg aatataataa tggaaaaatt agaaatagaa gaaataaccg taagtgaata
    62281 cgataatttg gaaggcttaa tatgtcaaaa gtcaaaaaaa atgtattaat attttttgat
    62341 ttttaaaacc gattatgaca aaaaaaatta ctcctctttg ttacaattct taatataaac
    62401 aaaagaggag gtttttttat gcaaagaagt gtagcagttg tgaagaataa gactgtaaaa
    62461 ccaaatgtca taaaattaat aagcggatat attgatttta ctacggcggc attcgctgtg
    62521 atgggatttt tacttagtag gtctattata gtagactctg tagctccttt aggaattgcc
    62581 ttttttatat gtgcatcaaa gattgataag tacaagatac ctgtattcat atcaacatta
    62641 ttaggaatat tgttatcatc taatgatttt ggaaatgtag caaaatatgc tgtgtgcctt
    62701 acaatattta tggctatgaa taaaaaatta aaattatcag attcaattgc taaggttgca
    62761 tttataggtg caataatact acttccaatc tccatgggac aagctttctt ttcaaatagg
    62821 tatgtatatg gtcttcttat agcaggagta gaagcaataa taatgtttat atctatatat
    62881 gtgttttctt atgggatagg tttaatggcc aatgtcaaca ataggatgtc tgtacggaca
    62941 gaagaagcta tatcaataag tttactgcta acctttagca taatgggaat aggagatata
    63001 tctctgtttg gaatatcaat aaggaccatt ttatcgaccg tattgatatt gctgacctca
    63061 atagtaggtg gagctaccat gggagcatct agtggtgtaa ttattggtgt agcatccatt
    63121 ttaaataata tgacatcagc tgtttatatg gggatatatt ctttttcagg attaataagt
    63181 ggagcattta ataaaataaa taaatatttc tgtatactag gatatattct aagttggaca
    63241 ataatatacc tatatacttc tggtattact tctaatatga tgcaattaag agatatacta
    63301 ttaggttgtt tgatagtact agtattgcca gagagattat ttaataagat tgaaaaatta
    63361 ataaaaagta atgtggcttc aaatgaaatc gtatacgatt atattatgag aagcaaaaac
    63421 ctaactaata gcagattgaa cagtatttat aaaacttatg atgaccttgc agatacattt
    63481 gataagataa gagaaaaaga caaagtgcta gaccaaagag atatagctaa tgtaatagat
    63541 atgattcata atgatgaatg taaaagttgt agtatgagaa gaatgtgctg ggagtcaaga
    63601 tttaatcata catacactat gatatataac attcttgaaa aaattgagga gaaaggggag
    63661 ttaagtctaa acgatatacc taaaaatttt agaaaggaat gtatgaaacc agagtcgata
    63721 gtgaaaatat caaatcacta ttacaaaatg tttgtattag attatgattg gagtgtgaag
    63781 ttttcagaaa gtagaaagtt aatagcaaat cagataagaa gtatttcaaa atccattaaa
    63841 tccttatctc aagatttaga aggtgacata atgctagata tagaaaagga aaaaaatata
    63901 tatgaacagt tagaaagata tgatataaca gttgataaag taagttactt aacaaaaagt
    63961 aacaatgagt ttgaaatatc aatagaaaag aaaacttgtc atgatggatg tatgtgtgaa
    64021 gataaaattg taaatataat ttcagaccta gtaggtgaaa atatgtctgt tagaaaaata
    64081 ggatgtcact gtttaggagg taaatgcaag gcaacattcg ttaaatctca aaaatataag
    64141 gctgttacag aagtttcagc aatgtcaagg gatgggcata tcctttgtgg agacaattac
    64201 acatacatgg agataaatga tggtaaatac atgatggcta taagtgatgg tatgggaaag
    64261 ggtaaaaaag catatgaaga atcttctgcc actattgata tactggaaaa aatgatagat
    64321 gcaaaaatta aagatgagat agtcattgat actataaata atatgttgtt gttaaaatct
    64381 tcagaagaga tgttttcaac tctggatttg ggaattttag atttaaaacg aggttgttta
    64441 gaaactataa agatgggagc gtgttctact tatataaaaa gagaggatgg agaagttgac
    64501 ttaatatcat catcatcatt acctgtgggt atattatcag atgtaaaaat tgatagaaaa
    64561 aatgtaaaag ttaaggaagg agactatgtt ataatggttt ctgatggaat tgtagatgca
    64621 ggaagaaata acaatttagg agacaattgg ttaatatact tcttaaagaa tatagagact
    64681 acaaatccaa aggaaatttc aaatttaata ttggatagag cattagagtt acaagcgtta
    64741 caaatcgaag atgacatgac tgttttagtt acgaaaatat gtacaaaata aggtttacaa
    64801 gattatgtgt ataagatgtg gataacttgt gtataatatg ttaatagact tttgaaaaaa
    64861 gtatagttat taacaaaaat aacatataaa tcaacaaaat ttgttgataa gtatggcaga
    64921 aatgttaata aaatgtaaaa aaagaaaaaa caaaagctat tatcaaaaga gattcatgtt
    64981 gaaataacta aatttctaag taaagaaaac ctgtgaatat gttgattatt atgtggataa
    65041 ctattaattc gatatttatt tatatagtat gaataattga ataatatatc taaaaaaagc
    65101 catcctatta ttaagtaaat ttattgaaag gatggctttt tatgaataga aaattgtgca
    65161 aagcaataat acctttattt atttctattt tttgcatgtt aataataagt ataaaagctg
    65221 accaaggata tcaaaagaat aatgacagag caattgctgt catgaataat aatgatactg
    65281 aagatgatgc tgaaaaaaaa caagaagtag actatgaaaa aacatgttgg aatttgcaat
    65341 ctttgttcaa aagtgatgac caatggaaaa aagaacttaa gagttttgat aaagatacta
    65401 aagagttgaa aaattacata ggtaaagtaa caaaatcgcc aacacatttg tcttttgcct
    65461 taaacattaa ggaaaaactt gatataagac taaataaact ttctgcctat gtaaaattaa
    65521 aacaagatac taataaaaat tcatataagt acttagatat gagtgatagt atgagtaaat
    65581 catatgggaa ttatatgggg atttgttcag atttagaatt agaaatacta aaattatcaa
    65641 acaaagatta caagaaaatt atttcaaata aaaatataaa taggaaatat ggtgcatatt
    65701 taagagatat aagaaggaat aaagtacatt atttggatga taaatcagaa gatattctaa
    65761 gcaaagtatc ttcaataagt agtcttccaa gccaagtata tgaattattt agaaatatgg
    65821 atagaaaaac taatttgaca ccagcgcaat atgcaagtga attagagtca gtagatagag
    65881 aaaatagaaa aaaagcttat caagatgaac ttataactta caatgataat ataaatacaa
    65941 ttgcaggttt aattactggt caagttaaaa agaatatttt ttattctcag gaaagaggtt
    66001 atgagtcttc tttagaaatg tacttggaat ctgataatgt agatgaaaaa gtatacaata
    66061 atttgataag gactgtaaat agtaatatgg acagtctaca caaatatata gatttaagaa
    66121 aaaaagtatt aaaattagat aaggttcatt catatgatat gtttgtgcct atggttaagg
    66181 ctgttgataa taatattaat tatgaaaagg cacaaagtat agtatattca gcgttgtcac
    66241 ctttaggaaa agaatacaat gatgtagtat ataaagcttt caatgaaaaa tggatagatg
    66301 tttattcaca tgaaaataaa gtaagtggtg gatactgctt atctgtttat gaaaatcatc
    66361 catatatact tttaaattat aataattcat taggttcagt ttcgacttta tcacatgagc
    66421 ttggacatgc tgtatatgaa tacttaagtt ctaagaatca gaattatttt aattcaaatc
    66481 cgtctatatt tactcacgaa gttgcatcta caacgaatga agcattactt tacgagatgc
    66541 ttataaaaga agctaaaggc aatgatgaaa aagcttatta tataacacag tatttagact
    66601 tgataaaaga tactctttat acacaaacta tgtatgctga atttgaaaaa actatacacg
    66661 agttagtaga aaaaggaaaa agtgtaaacg cattagtatt aaatgatgtt tggggacaac
    66721 ttcttaaaaa atattatgga caaagctatg aattagacca attatctaag gtcggatggg
    66781 ctagaatccc acatttttat aatagtttct atgtctataa atatgctaca ggttgtagtg
    66841 caggagtaag ttttgcccaa gacatcctaa agaatggttc agataactat atgagctttc
    66901 ttaaaaaggg aagttcagat tatccaataa acttgttaaa atcaagtggc ataaatttaa
    66961 ctaatacaaa acccatagaa aatacaatca aaaaatttga tagtttagta gcagaacttg
    67021 aaaagctatt ataaacatta ttgtaatcca catggtaaat atatcgaatt aatgataaaa
    67081 tatactaaaa gtttaaagtc ctatcaagat aggacttttt atttattaat tagtgggaga
    67141 tgattctatg caagttaaag ttaaaaaggc tgtaatacca gcagcaggtt taggaactag
    67201 atttttgcca gctacaaagg cacaaccaaa agagatgtta ccaatagttg ataagccaac
    67261 tctacaatac ataatagaag aagctgtggc ctcaggaata gaggaaatac taataataac
    67321 aggtagaaat aaaaaatcta ttgaagacca ctttgataaa tctgtagaat tggaacttga
    67381 tttagagaaa aaaggtaaga aagaattgtt ggaggtagta caaaacatat ctaacatgat
    67441 taacatacat tatataagac aaaaagagcc aaaaggattg ggagatgcaa tttattgtgc
    67501 gaggcatttt ataggtgatg agccgtttgc agtaatgtta ggggatgata ttgtagataa
    67561 tgatgtacct tgtctaaaac aactaacaga tgcatatgag gaatatagaa ctacaatatt
    67621 gggtgttcaa aaggtaaatc aagaagatac taataaatat gggataatag aagcaaaaaa
    67681 tatagaaggt agagtttaca aggtaaaaga catggtagaa aagccagagt caggaaaagc
    67741 tccttcaaat attgctattt taggtagata tataataact cctgaaatct ttgatattct
    67801 taaggattta ccaccaggta aaggtggaga ggtacaactt acagatgctt taaaaatatt
    67861 atctaagaaa gaagctatgt atgcatacaa ttttgaaggc aagagatatg atgttgggga
    67921 caagctagga tttttagaag ctactgttga ctttgctcta aagaaagaag accttaagga
    67981 agattttata aaatatttga aacatgtatg tagtgaattt gataaaaata acaatgtgtt
    68041 atacaataat acagatgaaa aaatagattt aattgaagtc aatgaagcta gagaacttga
    68101 aattcaaaaa taattaatga aaggtgatgt atggtggcaa aatcaagtca gaaaagaatt
    68161 aatagaataa tagctgttgg gattgtggga atcctcgtaa taacgagtat aacagctgtt
    68221 ttgagtatga ttgcaactat gtaataagat aaatgacagc agttgatata cataaatata
    68281 aaaaccatat ataacttgat gtagtcaaaa acttacaata ttttagttat atatggtttt
    68341 tagaatttat aaatgtaaaa aaaaattttt ataatagttg catattttaa aggaaaatat
    68401 tattataaga tataaatata gtgataaatt tataaaaacg tgctaagatt ggacttgaaa
    68461 tacagtaata tagtaggtaa taatgtttta aattttattt attgaccata atatataaat
    68521 aatgatatta ttagacttaa ctgtttaaat aaaacttttc tttttcatgc cttcaatttc
    68581 caaaataagt atgtatataa atgaatatat agatgaggag gatttttttg attttagatg
    68641 ataaagtatt agaaggatta ggtagtaaga ccttagttga gctacgagag atagctaaag
    68701 aattaaaaat aaaatcaatt actacatata agaaaaatga gttaattgag attataaatt
    68761 ccaaaagtaa aaatgaggaa aaagtaaacg aagagactaa agaaaaaaat gaagatatta
    68821 aagaagacat aaagaataga aaagaaaata tagagcgtga aagtatagaa aaagaagttg
    68881 aatataagag ccctaccaaa tcatacaaca agaaagaaat agatacccaa aatatttccc
    68941 aaaaccaaga aaatagaaat caaagaaatg actataataa gacaacgagt gtaaatgata
    69001 gtaataagtc atcaaatata tctaatagaa tggtcagaaa taataataaa aactattata
    69061 tgcctaaaca agttgatgaa tctaagatag tagatgaatt taacacatca aaagaggatg
    69121 aagtagtagg tgtacttgaa attctgccag atggatttgg ttttttaaga ggttcaaatt
    69181 atttgtctac tgaaggagat gtttatgttt caccatctca aataagaaga tttaatatga
    69241 aaacaggaga caagattaag ggaataacta gacatccaaa aagtggagag aaatttagag
    69301 cacttttata tgttcaaaaa ataaatgatg aaaaccctga cacagctata caaagaaatg
    69361 cgtttgagac attaacacca atatttccag aagaacgact tacactggaa actaatagaa
    69421 atgaaatagc tacaagaatt atagatttaa tttcacctat aggaaaggga caaagaggat
    69481 tgatagtagc acctccaaag gctgggaaaa cagttctttt aaaaagcgtt gcaaatagca
    69541 tagctaaaaa tcatccaaat gttgaactta tagtactcct tatagatgaa agaccagagg
    69601 aagttactga tatgaaagaa tctattgaag gagacgttat atattcaact tttgaccaag
    69661 tatcaagtca tcatgtcaag gttgcagaga tggtgttaaa tagagctcaa agattagttg
    69721 aacatggtaa agatgtagta attttactag atagtataac tagattggca agggcatata
    69781 accttacaat atctcctaca ggtagaactt tatctggagg tattgaccct ggtgcacttc
    69841 atggacctaa aaagttcttt ggtgcagcaa ggaatattag acagggtggt tctttgacaa
    69901 tattaggaac agcattggtt gaaactggtt ctaggatgga tgatgtaata tttgaggaat
    69961 ttaaaggtac aggaaatatg gagctacatt tagatagaaa attagcagaa aaaagaatat
    70021 tccctgcaat agatatttac aagtctggta caagaagaga tgatttattg cttgatgatg
    70081 aagaaaagac tgctctttgg agattaagaa gagaaatgag taataattca gtaatggaaa
    70141 ttacagataa agtcattgaa cttataaaga gaactaagga caataaagag tttgtaaaat
    70201 caataaagaa tttgtaaaat caataataca aatgcaaata tggattatat aaactaatag
    70261 aaaaatcact tgaatggcat aataagttgt gctataataa tgtagttgat aatgtaaaaa
    70321 gaaagttaat ataattaatt tttttaaata aagagaagag gtgactataa tgcaaaagga
    70381 aatacaacca aaatacaatc cagttgaagt gcgttgtgct tgtgggaaca catttgttgc
    70441 tggttcaact aaggacgaaa taaaagttga aatatgttca gagtgccatc cattctatac
    70501 aggaaaacaa aagaacatag aaaaaggtgg aagaatcgac aaattcaaga aaagattcaa
    70561 aatggactaa tttttataaa agtggagttg gaggaagcca actcctattt tattacaaaa
    70621 aaacattcat attctacttt aaattgtctt tttgtattat aataataaat atgtaaaatt
    70681 gagtattcta aatacaataa aatgaggtga gtggatggca aaacaagctg taggtgggca
    70741 agctgttatt gaaggtgtaa tgatgcagtc aaaagacaaa agagcggtag ctgttagaaa
    70801 aagtgacgga gaaatagcac taaaagaaga tagaataaaa agttgggtaa gagataagaa
    70861 tatagataag ataccttttg ttagaggttc ttttgttatg atagatacaa tgattcaagg
    70921 gataaaaagt ttaaactttt cttcagagtt ttttatggaa gaagctgaag aggataaatt
    70981 tgatttattt ataaagaaaa tttttaaaga taaggcaaat gatataatta taatattttc
    71041 attggtcata gcaatgttac tttctgctgg attattcatt tttataccta cattggtagg
    71101 aggagctttt tctaaagtaa tgcctaatga ttttatgctt aatttaatag aaggaatcat
    71161 aaggatagct atattatttg catatatagt attgatttca cgaagtaagg atatagaaag
    71221 agtctttcaa tatcatggag cagaacataa atctatatat tgctatgaaa atgatttaga
    71281 acttacagta gagaatgcta gaaaatttaa aagattacat cctagatgtg gtacaaattt
    71341 cctatttata gttatggctg tatcaataat attgtttgca ttttttggtt ggccaaatcc
    71401 aattcttaga atatttatga gaattatatg tgtgcctata gtagcaggtt tatcttatga
    71461 ggtaattaga gttcttggga aatatgataa tggatttact aaaattattg catatccagg
    71521 aatgatgttg caatatttta caacaaaaga gcctgatgat gagcaattag aggttgcttt
    71581 ggaagcattg aaagcagtag tagattagag aaaaggatat ttgttatgac gataaaagat
    71641 ataattatta aatattcaga taaactaaaa gatataagtg atactccaag attagataca
    71701 gagttattgt tacaaaaaac attgggtgtt gatagattat atattcactt aaatctgaat
    71761 aaagagctaa ctgaagaaca aaaaacaaaa tttatgggtt ttgcagaaga aagattaaat
    71821 ggaagaccaa tagcatatat agttgaaaat agggagttta tgggattaga tttttttgtt
    71881 aaggaaggcg tattgattcc aagaccagat acagaaactt tagtagaaga aataattgaa
    71941 atatgtagag aaaaaaaaga tgtaagtata ttagatatag gaactggttc tggagctatt
    72001 acaataagtt tagcaaagta cattgaaaat tctaaaatca tgtcttttga tatatcagag
    72061 acagcattag aaatagctaa aaaaaatgct attataaatg aagttggtga aaaaataaag
    72121 tatattaatt ctgatttatt tacagcaata agtgatagta acataaaatt cgatatcata
    72181 gtttcaaatc caccatatat taaaaaacaa gatatagaaa ctctgcacaa acaagttaaa
    72241 gattatgaac catataatgc tcttgaaggt ggagaagatg gattagactt ttatagaaga
    72301 ataacagaac aaggtaagaa atatttaaat aagtgtggaa tattagcata tgaagttggt
    72361 cataatcaag ctgaagatgt aataaatatt atgaaaagta atggatataa aaaaatatac
    72421 acaaagaagg atattcaagg cattgataga gttgttatag gttacaatat atgatataat
    72481 caacaattga tatgttacat ttaatcgagg tgaaagtatg ttaaaaaaat tagaggtatt
    72541 ggaagataca tataaagact taagtgaaaa aataggtgat ccggatgtaa taaatgatca
    72601 aaaagtttgg cagaaatata taaaagaaca tgctgacttg gaacctattg ttatgaaata
    72661 cagagagtat aaaagcgttt tagatagtat aaaagaatca aaagaaattt tacaagaaga
    72721 gtcagatgaa gaattaagag aattagctaa aatggagtta gctgagatgg aagaaaaagt
    72781 agcacctctg gaggaagaaa taaaaatact attattgcct aaagacccta atgatgataa
    72841 gaacgttata gttgaaatta gaggtggagc tggaggagat gaagcagctc tatttgcggg
    72901 tgatttattt agaatgtact caaggtatgc tgaaagaaga agatggaaaa tagaattatt
    72961 gagtgcaagt gatactggag ttggtggata taaagaagta tcttttatga taaaaggtaa
    73021 aggtgcttat tcaagattaa agtatgaatc tggagttcat agagttcaaa gaataccatc
    73081 aactgaatct ggtggaagaa tacacacatc aacttctact gttgcagtat taccagaagt
    73141 tgaagatgta gaggttgaaa taaatccaaa tgatttaaga atagatgttt tccgttcttc
    73201 gggtaatgga ggacaaagtg tcaatactac tgactctgct gttagggtaa cacatatacc
    73261 tacaggtgaa gtagtatctt gtcaagatgg aaaatcacaa ttaaaaaata aagagcaagc
    73321 tttaaaaata ttaaaagcta gactttacga taaagcattg gcagaacaac acaaagatat
    73381 agcagcagaa agaaaaagcc aagtcggaac aggagacagg tcagaaagaa taagaacata
    73441 taatttccct caaggtagaa taagtgacca tagaataaat ttaactttat ataagttaga
    73501 tgcattttta gatggagata tagatgaaat gatagatgct ttaattactg ttgaccaaac
    73561 agaaaaaatg actgcaatat aagtaatgtt ttaaagaagc tgtttcttcc tagaaattat
    73621 tttctatttt gaaacagcta ttttgcattt taggtcatgt tatcatattc tattgtatat
    73681 aattgttata tacaagtata ggagggttat atgatactaa aagtaacaat aattgggctt
    73741 ttggcaggtg ttatagggac aggattagga ggagtaatat cagccatttt taaaagagag
    73801 gtcgataaat atctaagttt ttttatggga ttatctggtg gaataatgtt ggctgtagtg
    73861 gtgtttgatt taatgaaaga atccatggac aaaatgggga taatcaatac agttatattt
    73921 acgtttgttg gagctctcat aactatgtac ataaaaacaa aattagatgt gtctggaaat
    73981 atggcatctg gatatcttat attcataagt atattactac ataatttacc agaaggacta
    74041 gccattggtt cttcttttat gtcaactgaa agtttaggta ttacacttgc tatagttata
    74101 ggtctacata atataccaga agggttagct atggcattag gcttagtttg caataaaatg
    74161 aaactaagta aagttatttt gtttactgta atagctggat tacctatggg tctaggaagt
    74221 tttttaggtg tttattttgg aggagtattt acttctctta taggagtatt tcttgctaca
    74281 gcaggaggta ctatgatgta tgttgtattg gaagaaattt ttccacattc aaaaagtgtg
    74341 tattgtataa ttggtttctt gttaggtaca atgattgtaa attatatata aaattaaaat
    74401 gaaagcaggc atacaaaaga tgaaaactat tataagtaat attgatataa ataatattga
    74461 ttatgaggaa ataaaaatac aagcaaaact tcttagagaa ggtaaaacag ttatttttcc
    74521 aactgagaca gtatatgggt tgggtgcaaa tgcattagat gaaaatgcag taaagaagat
    74581 ttatgaagct aaaggaagac ctagtgacaa tccattgata gtccatatat atgaaaaaga
    74641 agaagtatat gacttagcca aagatataag tgataaagct aaacttgtta tagaaaagct
    74701 ttggccagga cctataacaa ttatattaaa taaaaaagat ataattccat acaaaactag
    74761 tggagggctt gatacagttg caataaggat gccttctaat gttattgcca gggcaataat
    74821 aaaagaagct ggtataccta ttgcagctcc ttctgcaaat atctcaggtc gcccatctcc
    74881 aacaaaagca aaacatgtat atgaagagat gaatggaaga gtggatggaa tagttttagg
    74941 aggagacagt aattttggat tggagtcaac tgtattggat ttaacagaag agactcctat
    75001 gatactgaga ccaggaagta taactaaaga agttttagag gaacttcttg gagaagtaaa
    75061 gcttgaccca tcattaagta aaaaagaaga taatcaaaaa gctaaagctc ctggaatgaa
    75121 atataaacat tattctccaa atgcagatgt atatataata tctggaaaaa gagaaaatgt
    75181 agcaacaaag attaatgata tgataaaatc taatagagac aaaggtctaa agacaggtgt
    75241 aatgtgtatc agtagaaacc gagagtttta tgatggagaa gtaatcgatt taggaaactc
    75301 tcttgaagaa gttgcaagta atctgtttga tgctcttata gaaatggaca aaaagggcgt
    75361 tgatgtcata tattcagaag agttccctaa gactggagtt ggacaagcaa ttatgaatag
    75421 actactgaag tcagcaggat acaaagtgat aaaggcttaa gagggagttg taaaatatga
    75481 atatacttat tgtgtgtaca ggtaatactt gtagaagccc tatggctgag gctatactaa
    75541 ggaaagcaat taaagaatct ggaagaagta ttgaagaata ttcgatatca tcagcaggta
    75601 tatctacagc aaatggaatg ggtgcttctg aaaattctat agaagtacta aaagaaatcg
    75661 gtatagactt atcaaatcat agaagtaaag taattactaa aaaattaatt gatgaatcag
    75721 atataatact aacaatgact aaatctcata aagaaatttt agtacaagca gttccaaaat
    75781 gcaaagaaaa agtgtatact tttaaagggt ttgcaaataa aaatgaggaa gatatatctg
    75841 acccatttgg tggaaatttg gatatttata gaagcactat gagagaaata atgtattctg
    75901 tcaacgaaat agtaaaaaaa atatgaaacg gaggataaac aaatgaagat aggattaggc
    75961 tgtgaccatg gaggatataa tttaaaaaaa gaaataataa gctatttaga aagtaaaggt
    76021 atagaatgtg tagattatgg aactaataat gctacagatt ctgttgatta tcctgtttat
    76081 ggagaaatag ttgcaaattc agttataaat aaagaagtag attatggaat attatgttgt
    76141 ggtacaggga taggaatatc tttagctgct aataaggttc ctgggataag atgtgcagtt
    76201 gtatcagatg tattttctgc aaaaatgtca aaagcacata atgatgcaaa tatgttatca
    76261 ttaggcgaaa gagttttagg aaaaggtcta gcacttgaga tagttgaagc atggattaat
    76321 acggattttg aaggtgatag acatgctaga agagtaaaca tgattaaatc aatagaagaa
    76381 aaacataata aataataaaa attacagttt tatcaggagg aattatcaaa atgagcaaag
    76441 tggtagagac aaaccatcca ttaatacaac ataaattaac tttaatgaga gataaaaata
    76501 ctggttctaa agactttaga gagcttttaa ctgaaattgc aatgttaatg gggtatgaaa
    76561 taacaaaaga tataccatta aaagatgtag aaatagaaac tcctattcaa aaaacatcat
    76621 ctaaagtagt tgcaggtaaa aaattagcaa taattccaat tttaagagca ggtcttggaa
    76681 tggtagatgg attagtaagc ttaatgccag cagcaaaagt tggacatgta ggactatata
    76741 gagacccaga aacattaaaa ccagttgaat attattgcaa gcttcctcaa gacataggag
    76801 aaagagatat aatagtagtt gaccctatgc ttgcaacagg gggttctgct gtagcagcta
    76861 tagatttact taagtctaaa ggagctaaaa gtataaaatt agctaattta gtagctgcac
    76921 cagaaggtat agcagaagtg caaaaatatc atgatgatgt tgatatatat gttgcatcag
    76981 ttgacgaaag attaaatgaa catggatata taattcctgg tcttggtgat gctggagata
    77041 gattgtttgg aactaaataa aaataaataa ctataaatat ttattaggga ctttcttata
    77101 tagtgtatat aattttatgt aagaaggttc ttttttatat attttttctc aaaataggaa
    77161 ttatgaattg ataaatttct cgaattgaga ataaaaagtt tttaccaatt aaaaaagatt
    77221 gcttatttta caaggtttta tagaatagta gtctatttta atgtggcatg ttagttgctt
    77281 acgattaaga ttataggtat taagtgtatt agttaaattg agaattgaat attaataata
    77341 ttattgggag tggtaataca tgaagaattg tatagcagta agaggggctg gagatttagc
    77401 aacagcagtt attcataaat tacacaacag tggttttaaa gtagttgcgt tagaaataga
    77461 agagccatta gctataagaa ggcaaatttc tttttgtgag gctgtttatg aaaaaaaagt
    77521 aactgttgaa ggtgtagaat gtatattttg caatactgaa aaagaaatag aagaagtttt
    77581 atctcaacat aaagtagcct tgattataga cccaaaagga gaaaaattat ctaagttaaa
    77641 tccaatcgtt ttggttgatg gaatactcgc taagaaaaac ttaggtacaa ctaaagatat
    77701 ggcaccactt acaatagctt taggtcctgg attttgtgca ggagaagatg tagatgttgt
    77761 tatagagaca atgagaggtc ataatctagg aagaataata actaatggta gagcagaaaa
    77821 aaatacagga gtaccaggag caataaaagg tttttctaaa gagagagtta tgcattcaca
    77881 gtatgatggt ataatggaaa atgtatgtaa gataggtgat atagttgaaa agggagacct
    77941 actttgttat attaataatt atgaaaaaaa acatgaagtt agagcaacaa tatctggagt
    78001 ccttagaggt ttattaaagg atggagcaaa ggtgaacaaa aatttaaaaa tactagacat
    78061 agaccctaga aaagaagaag ttaagaatgc ttttacaata tcagataaag ctagatgtat
    78121 agctggaggg gttttagaag ccatactaaa caatgggatt tatccccaaa attaatttat
    78181 attagataaa gctattaata ttttattaag atgatataat aaatttaata gattaaagag
    78241 agcatatgac gggtatttaa aatttaaatg gtaaaaatgc tcttttttta ttggacattc
    78301 aattaacatg tgtatataat ataaaaataa gtatttattt aggttgaaat ctaataaata
    78361 tataatacca gtacataagc aaagaggaga aaagtaaatt atgagaccat catgggatga
    78421 atacttcatg gaaattgcag aagtagtgaa aaagcgttca acttgtatta gaagacaagt
    78481 aggagctgta attgtaagag acaaacaaat attaacaact ggatataatg gttctccgag
    78541 aaatcttgaa cactgtgaaa atattggatg taagaggcag gaattaaata ttccctcagg
    78601 agaaaggcat gaattatgca gagcattaca tgctgaacaa aatgcgataa tacaagctgc
    78661 tcataatggt attagtgtag atggggcaac tttgtatgtt actacaagac cttgtgtttt
    78721 gtgtgcaaaa atgtgcataa atgcaggtat attgaaaatt gtttatgaag gtgattatcc
    78781 agatgatatg tctacagaat tattaaaaga agcaggaata gaactcataa aattttagtg
    78841 gataaaattt atatgacaat aaatgtcaaa ttatgacact gaaatacaat ggtatcaaat
    78901 gattaaaaga aagtatttga aaaatcatca gattagtagt aagatatatt ttataattaa
    78961 ataaatttat gagatagatt aattacatgt tatttatttt ataataatga gggatactat
    79021 ttatgagtaa aagaaataca catacagaaa ttgcaaagtt gtttagttta ataagtcaaa
    79081 taggattgat gattgtaata tcaatattag gatgtacttt cttaggaaaa tttttagata
    79141 gtaaattgaa tactactcca gttctgacaa taatattttt attgttgggt gttggaggtg
    79201 cttttagtgg tgtttataaa actctaatag tatatacacg aaggaagtga tatattggat
    79261 ataaaattac ttaaccaggt aaggtcagta acaaaaggta tagtaatatt tgatgtagtt
    79321 ttaattgtgc taatgttgat aacatcaaca ttaagtaaac cagtattatt aggacttata
    79381 tttggctcta taatagctat gttaaatttt agattattgg cgatatcact ggaaaaatca
    79441 gtgacatttc ctgctgggaa ggcacaagct tatgcatcag cacaatatgc tattagatta
    79501 tttataatgg cagttgttct aattgcatca gctacagtac cacatttaaa tataatcgga
    79561 acagcattgg gattattgag cacaaagttt gtcatattat caaaaaactt tataaataaa
    79621 ttaaagagga aggaggcata agtatgaatc aagcgcatta ttatctcata ggaaacttta
    79681 agattagtga aacaatacta gtaagttggg gaataatggc ctttttagcg atagcatctt
    79741 attttttgac tagaaactta aaaaaagttc caactagtaa agttcaaata ttcttagaat
    79801 ttgcagtagg tggtcttgct aaaatggtta cagatgttat gggtaaaaat acagtaaaaa
    79861 gaatgccata tatgatacca tacataggaa gcttgttttt atttttcgca tgttcaaatt
    79921 taagcccatt acttggatta aggtcaccaa caaccgactt agacacaact gctgcatggg
    79981 caatgattac attttttatg atttattttg caggagttaa atttaagggg ttatcatact
    80041 ttaaagaatt ggctcaacca cttgccataa tgttaccaat caatattata ggtgagttag
    80101 ctagaccaat atcattaagt ttccgtccat ttgggaatat tttaggtgga acaataataa
    80161 tgggtctgtt ttatcaactt ttaggtttta tatctagttt aataccagga ttatcaatac
    80221 caattggaga aatattaata ccagtcccat tacacttgta ctttgactta tttgcaggat
    80281 tgttacaagc atatatattt ataatgttaa caatggtatt tatatcaagt gcaggagagt
    80341 tagattaaga aatcaactta tattaagata aaaataaaat aatttaaaaa attaaagttt
    80401 taaggaggaa ataattatgg aaacagcaat agtagcggca gcatcagcaa taggagcagg
    80461 gatagcagtt gcaacaggta taggtgcagg tataggtcaa ggtatagcag cagctaaagc
    80521 tgcagaagca gtaggaaacc aaccagaagc taaaggtgat ataacatcaa ctttattact
    80581 aggagttgct atagcagagt cttcagcaat atatggtttg gttatatcaa taatacttct
    80641 attcgtaaat ccattcttta aatacttagg aatgtagatt tagtccttaa atattttgag
    80701 ataggtttat aggtaaatca tctcaaactt ataatcatga gatgaacttt atcatctcgt
    80761 gattataagt agttatgatt tatggaaagg aggataatta tggaaaaagc actagtaggt
    80821 ataacgtggg aatttgtgtt ccaaattgtt aatactttta taatattttt acttctgaga
    80881 aagcttttat tcaagccagt attaaatata attgaatcaa gagaaaatga tattaaaagt
    80941 gatttggcag aaggcgaaaa agcaaaaaat gaaggtttag ctctgaaaaa agaatatgag
    81001 tcaaaaatca attttgccaa ggatgaaggt caagaaatca taaaacaagc aactataaga
    81061 gcagagcaga aatcagatga tatagtaaat actgcaaaga aagatgctct tgatataaaa
    81121 gaaaaagcaa acaaagatat agaacaagaa agacaaaagg ttataaatga aatcaaaaat
    81181 gatatatcta acatagcact acttgcagca tctaaagtta ttgaaaaaga tttagataaa
    81241 tctaaacatg aagaattgat agaaaacttt ataaaagagg taggggaagc taaatgataa
    81301 atgtaatagc aaatagatat gccgaagccc tatttcaatt aggagaagaa gaaaattcaa
    81361 ctgatgtctt attcaaagaa ctagaaaaag tagtagatat gatgactaaa gttagtaaag
    81421 atttctacaa agttttaaaa tcaccattag tttcaaaatc agaaaagaaa aacttggtag
    81481 aaattatttt tagtaaggaa gtaagttcta acataaaaaa ctttttaaaa gttttagtag
    81541 ataaagatag aatatcatat ttagaagata tcgaattagc ttataaagaa ttattaaata
    81601 agaaaaacaa tgtaattgat ggagtagcaa taagtgctat tccaatgagt gaaacagata
    81661 ttaaagaact tgaagtcaaa ctttcaaata aatacaacaa aaatgttact atagaaaatg
    81721 ttgttgacaa gactatacta gggggagttc tagttagaat tggaaatgaa caaatagatg
    81781 gcactgtgaa aactcgtctt gataagatga aagaaaagct atctgaagta atatcttaag
    81841 aatggcggtg aacccatgaa cttaaaacct gaagaaataa gttctataat taaacagcaa
    81901 ataaaaaatt atgagaataa agttgagttg acagatacag gtagtgtttt aacagttggg
    81961 gatggtatag cgagtgtata tggattagaa aaagctatgt ctggtgagtt gctagagttc
    82021 ccaggtgaaa tatatggtat ggcacttaac ttggaagaag aagtagttgg agctgttatc
    82081 cttggagatg acagtgaaat aaaagaaggc gatatagtta agagaactgg aagaatagtt
    82141 gaagttccag ttggagaagc tttaataggt agagttgtaa actcactagg tcagccaata
    82201 gatggaaaag gacctatagc gtacacaaaa actagaccag ttgaatctga ggcacctggt
    82261 ataatagata gaaggtctgt ttatgaacca ttacaaacag gaatcaaatc aatagattca
    82321 atgataccaa ttggtagagg tcaaagagag ttaataatag gtgacagaca aactggtaaa
    82381 acatctatag ttattgacac tatactaaat caaaaaggaa aagatgttat ctgtatatat
    82441 gtagcaattg gacaaaaacg ttctactata gctcaattag ttagctcttt agaaaaaggt
    82501 ggagctttgg attatacaat agtagtttca gcaacagcat ctgaatcagc accacttcaa
    82561 tatatagcac catatgctgg agcagctatg ggtgaagaat ttatgtacaa tgggaaacat
    82621 gtacttatag tgtatgatga tttaagtaaa caagctgttg catatagaga aatgtcattg
    82681 ttacttagaa gaccaccagg acgtgaggca tatcctggag atgtattcta tttacattca
    82741 agattacttg aaagagcagc taagttatct gatgaattgg gtggaggttc aatgactgcc
    82801 ttgcctataa tagaaactca agctggtgac gtttctgcat atataccaac aaatgttata
    82861 tctataacag atggtcaaat atacttacaa ccagagttat tctattcagg tgtaagacca
    82921 gcagttgacc ctggtatatc agtatcaagg gttggtggtt ctgcgcaaat taaagcaatg
    82981 aaaaaagttg caggaacatt aaaacttgca tattcacaat atagagaact tgcagcattc
    83041 tcacagtttg gttctgactt agatgaagat actaaaaaga gacttgctca aggtgaaaga
    83101 atcgttgaga tattaaaaca aggtgagcat caaccaataa aagttgaaaa tcaagttatg
    83161 ataatatatg ctgttataaa taatcattta gaggatattc cgatagataa tatagctaga
    83221 tttgaatcag aattgtatgc atttgtagat aataattatc cggaaatatc aagaaaaata
    83281 ttaggtggag aagacttcac tcatgattta acagatgcaa taaatgaatt taaagaaaag
    83341 tttgttgttg aagtataatc ctttttaaaa aaggaggtaa attaattggc aggagctgga
    83401 atcaaagcaa tcaaaacacg tatgggaact gttgaaagta caaagcaaat aactaaagca
    83461 atggaattag ttgcatcttc taagcttaga aaagcaaaag aaaaggctga agattcaaga
    83521 gaatatttta atactttata caatacagta aaagatattg cccaaacaac acgtggaatt
    83581 agaaatgaat ttttaaaaga aagagaagta aaaaataaat gttatgtagt agtagctgga
    83641 gacagaggac ttgcaggtgg atacaattcc aatgtattaa aggaatctgt ctctcatatg
    83701 aaaggtaaaa aggaaacagt gattactgtt ggaaagaaag cacatgaatt tttttctaaa
    83761 agaaactaca atatagcaaa agatataaat agtgttgaag cttgtggata tgaagatgcg
    83821 acagaaattt cacaaactat tattgacctg tataaaaaag gtgaagtaga tgaagtttat
    83881 attgcttata caaaatttaa atctgcttta tcacaagaag ttgaaatttt gaaattgctt
    83941 ccattagtct ttgaaaaaga tacagacgaa caaggaatgg cagtaaaaga agaaaaacaa
    84001 aatagatcaa aagtacaata tataccatca gcagaagcag ttttaagtta tattgtacct
    84061 cagtttatat caggtacagt atatggtgga attttggaat cttttgcatc agagcaaggt
    84121 gctagaagaa ctgcaatgga atcagccaca gacaatgcga atgaaatgct atctaattta
    84181 gagttaagtt ataacagagc aagacagtca gctgtaactc aagaaataac agagatagtt
    84241 ggtggagttg aagctctaaa atagggaggt taggaaatgg caaatgtagg taaagtagta
    84301 cagattgtag gagctgtact agatgttaag tttgatagtg aacaaagcct acctaactta
    84361 ttaaatgcgt tagtaataaa gttaggagat aaagaaatag ttgcagaagt tgctcaacat
    84421 ataggtgatg atactgtaag atgtatagct atgagtgcaa cggacggact tgtaagaggt
    84481 atggaagttg tagatacagg agggccaata agtgtccctg ttggagatga gactttaggt
    84541 agaatattca atgttcttgg aaaaccagtt gatgggaaac cagctccaaa atctgcacct
    84601 aaattaccta tacatagacc agcaccggcg tatgatgaac tagaaactac agcagagata
    84661 ctagaaactg gtattaaggt agttgactta ctagctccat atctaaaagg tggaaaaata
    84721 ggtctatttg gaggagcagg agtaggaaag acagttctaa tacaagagct tataaacaat
    84781 attgctaagc aacatggtgg tatttctgta ttttcaggag taggagaaag aacaagagaa
    84841 ggtaacgacc tttatggcga aatgagtgag tctggagtta taaataaaac agctctagta
    84901 tttggtcaaa tgaatgaacc acctggagcg agaatgagag ttgctttaac tggacttaca
    84961 atggcagaac attttagaga tgagcaagga caagacgttt tacttttcgt tgataatata
    85021 ttccgtttca cacaagctgg ttcagaagtt tcagcacttc taggacgtat gccatcagct
    85081 gttggttatc agccaacatt agctactgaa atgggtgcac ttcaagagag aataacatca
    85141 actaagaaag gttcaataac atctgttcaa gcagtatatg taccagcaga tgacttaact
    85201 gacccagcac cagctacaac attctctcac ttagatgcaa aaacagtttt atcaagacaa
    85261 atatcatcac tgggtatata tccagcagtt gaccctcttg aatctacatc aaggattctt
    85321 gaccctagta tagtaggaaa agaacattat gaagtagcta gaggtgtaca atcaatactt
    85381 caaagatata aagaacttca agatataatt gctatacttg gtatggatga attatctgat
    85441 gaagataagt taatagttgc acgtgctaga aagatacaaa gattcttatc tcaatcattc
    85501 acagttgctg agcaatttac aggaaatcca ggtcaatatg ttcctgttaa agagactgta
    85561 agaggattta aagaaattct tgaagggaaa catgatgact taccagagtc agcattctta
    85621 tttgtaggaa caatagaaga cgctgttaga aaagcgaagg gaagtatgta gtcatggcca
    85681 gtgaattttc attgaaagtt gtaactccaa gtaatacttt ttatgatgga gatgttgaaa
    85741 tgatagtagt tagaactaca aaaggagaca aaggggtgtt gaaaggtcat ataccatttg
    85801 tttcaggtat acctgtagga actttaaaga taaaaaaaga gggaagtttt aaagaggcga
    85861 aaatagcaga aggattcatt aatgtaactc aagataaaac tgtcatattg acagaatctg
    85921 ctgagtggat ttaataaatt aatttagagt ataaaaagtc attttgacca aaaaaacttt
    85981 tgggtaaaat ggcttttttg tgttttggtg ttaataaaat aacgataaaa ttgtaagttt
    86041 ttagtgataa taaattcaca aaatgtttaa atttactgcc aaattatgtt gtaattaata
    86101 agataaagaa gatttagata gcttttatgt aagtgaaaaa gtcttcatat aagaaataca
    86161 tataaaattt ttataaaatt taaaaaattt gcttagttgt gtagtataat aaataatata
    86221 atagatttgt atataatatt cattacaaat aattttaaaa gttacagttt tattataatg
    86281 attattaaat taagataagt aacataaact aaataataat gtgtattatc gatagtaaat
    86341 ttataaattc attattaatt attgaaagaa gtattataaa ttttctggag gaacaatgaa
    86401 tatatttgat attggcgtag atataattga aattgataga ataagaaagg ctgtagacaa
    86461 aaataatagg tttttggaga agatatttac agatagagaa atagagtatt ttaattctaa
    86521 gaattttaaa gcagaaagta tagcaggtaa tttcgcagcc aaggaagcta taagtaaatc
    86581 tataggtaca ggaattagat tgtttaattt taaagatata gaagttctca gaaatgaaat
    86641 gggaaaacca atagtaaaaa cttataataa tctagcaaaa atgtgcatag attataatgt
    86701 tttagaaata aaagtttcaa tatcacattc aaaagattat gctatagcaa atgcgataac
    86761 cataattaag gactaaggag tgattacatt atgatggata aaacagcaaa agaaataatg
    86821 acaacagatg taatagtagc aaaacaagat gatagtatag cagatgtagc taatatgcta
    86881 attgcagaaa aaataggagg tctgccagtt gtagattcag agaatagagt tgttggaata
    86941 atttctgaaa cagatattct taaaaaagaa aaatatatag aagcacctct ctatataaat
    87001 ctattacaag gattgatttt cttagatgac ttaaaaaaag ttgaaaaaga tataaaacaa
    87061 gtagctgctt ataaggttgg agaacttatg tctaaagata taataaaggt tcatgaagat
    87121 gataagtttg atgatgtagc taatgtaatg attaaaaaat caataaacag agttcctgta
    87181 gtagatgatg acaacaaact taaaggtata atttgtagat atgatataat aaaagcttta
    87241 tacaatgaat aaactgaagt aggaggtgtg atgtgagaaa aaagtggacc atagtatgta
    87301 ttatgttctt ggcactggtt ataattgtaa taggatgcca aaaacgacag tccacaaaag
    87361 aagaagtata caaagatttt caaaagcaga tttctgatat gaattattac agttgtaaag
    87421 ctgaagtaga agtagttgga aataaaagcc cacacaatta tgttttaatt catacttata
    87481 aaaaaaccga taactataaa ttagaagtaa tttccccaaa acatttaaaa gggaaaagta
    87541 tagaatatca aggtgataaa atattagtta aaaatccaaa gattagtgat gtagtggagt
    87601 tacctaatac aggaaaaaat aatcaatatc tttttgtagg agactttata aaaaactatc
    87661 ttcaaaatga ggagatgaaa gtaaagttat ccaaaggaca tttggtttta gagactttta
    87721 ttcctgggga taataaatat tttaacaagc aagtattata tgtaaatgct gacacaaaaa
    87781 atcctgaaaa aatggaagtg ttagataaag agggagtgcc aagatttaca gtaaaataca
    87841 aagattttga atacagaaac taagggggac taaagacatg caaaaaataa cagtgcctac
    87901 atgggcagag ataaatctag ataacttaag atttaactta aataatatta aaaatttatt
    87961 agaagaagat attaagattt gtggagtaat aaaagctgat gcatatggac atggtgcagt
    88021 agaagttgca aaattgctag aaaaagaaaa agtagattac ttagcagtag caagaactgc
    88081 tgaaggaatt gaacttagac aaaatggcat aacacttcct attttgaact tgggatatac
    88141 tccagacgaa gcttttgaag attctataaa aaataaaata actatgacag tttattcttt
    88201 agaaacagca caaaagataa atgaaattgc aaaatcttta ggagaaaaag cctgtgttca
    88261 tgttaaaata gactcaggga tgactagaat aggtttccaa cctaatgagg agtcagtaca
    88321 ggaaataata gaattaaata aattagaata tatcgattta gaaggtatgt ttactcattt
    88381 tgctacagct gatgaagtaa gtaaagagta cacttataaa caagctaata attataaatt
    88441 tatgtctgat aaattagatg aggctggtgt aaaaatagct ataaaacatg tatcaaacag
    88501 tgcagctatt atggattgcc ctgatttaag attaaatatg gtaagagcag gaataatatt
    88561 atatggtcat tatccatctg atgatgtatt taaagataga ttagaattaa gaccagccat
    88621 gaaattaaaa tcaaaaatcg gacatataaa acaagttgaa ccaggtgtag gaataagtta
    88681 tggactaaaa tacacaacta caggtaaaga aacaatagct acagttccaa taggatacgc
    88741 agatggattt actagaatcc aaaaaaatcc aaaggttctt attaagggag aagtgtttga
    88801 tgtagttggt agaatatgta tggatcaaat aatggttaga attgacaaag atatagacat
    88861 aaaagttgga gatgaggtta tactatttgg agaaggcgaa gttacagctg agcgtatagc
    88921 taaagactta ggaactataa actatgaagt gttatgtatg atatcaagaa gagttgaccg
    88981 tgtttatatg gaaaataatg agcttgtaca aataaacagt tatttgctaa aataaaacca
    89041 tgatattata atctgggagg cgattttgtg tacgataaga gtaaagaaaa aatagaagtt
    89101 actttacctg actctctgat ttctgaagtt gatagtatag ttcagatgga gaacagtaac
    89161 agagaagatt ttgcaaaagc tgcttttcag ttctatataa ctcagaaaaa gaaaattcat
    89221 attaaagaat ctatgaaaac gggttataga gaaatgggtc aaattaatct gtcactagct
    89281 gaattaggta tgacagttga agaagtatct tctgatgata aaaatgaagg gaagattgcc
    89341 caaggtgagt actaattgtg aaataaagcg tggtgattta tattacgctg atttaagtcc
    89401 agttgttggt tcagagcagg gaggcgttag acctgttctg ataatacaaa atgatgtagg
    89461 taataaatat agtcctacag ttatagtatc agctataaca tctcagatta ataaagccaa
    89521 attacctact catgtagaga taagttccaa tgaatatggg cttaataaag actcagtaat
    89581 tcttttagag caaattagaa ctatcgataa aaagagactg agggaaaaaa ttggttgtct
    89641 agatgaaaat atgatgataa aagtagatga tggacttcaa ataagtttag gattgtttac
    89701 tttttaaaga gggatttgtc ttttattaga caatcccttt tttcttttaa atatctctta
    89761 aggtttaatt ttaatgtact atgttaataa aattaaaaat aacgcaaaaa aatagcataa
    89821 aagtgatata ataatatgga attgatataa aattacgaac tcaagggagg taattgcatg
    89881 agagaccata aaggattaaa tgagattgcg cgtatcataa gaagagatat agtttcaatg
    89941 atacatagag ccaaatctgg acatccagga gggtcattat cagtagttga aatacttact
    90001 gcgttatact ttgatgaaat gaatgtggat tcttcaaatc ctaaaatgga ggatagagat
    90061 agatttgtat tatcaaaagg acatgctgca ccagcattat atgctacatt ggctgaaaaa
    90121 ggctattttg ataaggaaga actgaatgga ttaaggaaga taggaaggat gttacaaggt
    90181 catccagaca tgaaaggcac gccaggtgtg gaaatatcta ctggttcttt aggtcaaggt
    90241 ttttcagtag catgtggtat ggctatggca tcaaagttgg ataatgctcc gtggaatgtg
    90301 tatactttgc ttggtgatgg tgaggttcaa gaaggaattg tttgggaagc tgctatgagt
    90361 gctgcacatt ataaacttga taatttaatt gcttttttag ataataatgg acttcaaata
    90421 gatggagata tagaaagcgt aatgagttta ggttcaatag ttgataaatt taaagctttt
    90481 ggttggaatg taattgagat agatggacat gattttgacc aaatatttgc ggctcttgat
    90541 atagctaaat caacagttaa aaaacctaca atgatagttg caaaaactat aaaaggcaaa
    90601 ggaatatctt ttatggaaaa tcaagcagga tggcatggga cagctccaag tgatgaggag
    90661 ctagaaaaag ccttgcttga attaggaggt gctgacaatg agtaaaatgg cgacgagaga
    90721 agcatatggt aaagcattag taaaattagg tcaaataaat gacaatgttg tagtattaga
    90781 tgcagattta tcaaagtcta caaaaacaca tgatttttac aagtcatttc cagatagatt
    90841 ttttaatatg ggtatagctg aacaaaattt aataggcgct gcttgtggat tatcaactgc
    90901 tggtaaaata ccttttgcaa gtacttttgc tatgtttgct acgggaaggg cttttgagat
    90961 tataagaaat tcagtttgtt atccaaagct aaatgtaaaa atatgtgcta ctcatgcagg
    91021 tcttactgtt ggagaggatg gagcatctca tgaaagtgtg gaagatattg ctataatgag
    91081 agctatacca aatatgacag ttcttgttcc agctgatgga gttgaaacag aaaaaattat
    91141 ttttgaaata gctaagtata atggacctgt ttatgttaga ttagggagaa gttcagtacc
    91201 agttttattt gatgaagatt ataaatttga aataggaaaa ggtacagtct taagagaagg
    91261 aaaggatgta tcaattatag cttgtggaat tatggtaaat gaagctctat tagcacaaga
    91321 aaagttgcaa gaagaaggta taaatgctag agttataaac atgtcctcga taaaacctat
    91381 agacaaagat ttaatattag aatcagcaaa agaaacgaat gctattgtaa ctgtagaaga
    91441 acatagcata attgggggat taggttctgc tgtaagtgag gtagtaggag agtcttgtcc
    91501 aaccattgta aagaaagttg gaattaaaga tacatttgga gaatctggta ctccaaatga
    91561 attgttaaaa aaatatgaat taacttgtga tgacataata aagactgtta aagaagctat
    91621 tattgcaaaa agaatgtaag agatataaat tattcatgtt tgttaataat ataatatatt
    91681 taaaagagag gtataaagtg ttatattaat ttatatctct ctttttttta tatgatatca
    91741 atatatcaaa aatgtaataa aatattcaaa tttttacaaa aatagagaaa atattcaaat
    91801 atatattgac tattcagaaa aatatgacta atatataatc tatagagaaa ctaattttat
    91861 atataatgac tacttagata aaagaatcta aaaaaattat gagaggagga gtagggtata
    91921 aaatcagatt ataagtttta agttattata ctaaaaagct ataaaacagt tatcatgtat
    91981 tttatgttaa aggaaattgt aggtagttta tcgaattatt taatcagaag aaaaaatttc
    92041 acatggggag gtaactgaga tatgtcagaa aaagtaaatg ttaaaacagt catcagtttc
    92101 gcaggtgcgt atgtagcaac agtaatcggt tctggatttg caacaggaca ggaaataatg
    92161 caattcttct ctttttatgg ttttgcaggt attattggtg ggataatttc aatggtatta
    92221 ttctcatgga tgggtgcttc agttatgtca aaaggtaaag agcttcaact taaagaacct
    92281 atcaaaattt atcgtgttta ttgtggtaag tatttaggga tattctttga atggtttgga
    92341 cctttattct tatttggtgt tttcgtagta atgatttcag gagcaggagc aactttaact
    92401 gaatactatg gattaaatcc atttgtaggt agagtaggta tggcagtagt agcattatta
    92461 actgtttcac taggtcttga taaattatca aagatactag gtggaatagg gcctataata
    92521 ataatcttta cacttttagt tggtggtata agtttagcta aaaacatagg taatatagga
    92581 gaagctgcac aagttcttag cactgtaaag atagctaaac cagttccaaa tgcctatcta
    92641 tctggtgtaa tatatactac ttataacaca attgttgtta tggcattctt aactggatta
    92701 ggagcaagtg ctgctaacaa aaaagaagct atttgtggtg gtatattagg tggagtagca
    92761 cttatggctg cagctataat gatgcactta gctattcttt ctgatatagg aaacttatat
    92821 tcaaaagcaa taccatcatt attcttagca gataagattt caccagtaat tggagtttta
    92881 ttctcaataa ttcttatatt aggtatatat acaacagctg tacctttatt atggtcagta
    92941 actaatagat ttgtagatga taaacatcct aagtttaaat taataacttt aatagcagct
    93001 atattaggtc ttataggtgg cttcctacca tttgataagc tggttggtat tttatatcca
    93061 tatactggat atatgggcgt cataatactg gtttgtgttc tttatagaca gattacaaaa
    93121 acatctggat atcaagaagg aatcagtgac aaataagtat tttttaatat tgtaaactca
    93181 agagctatat gaaaacaatg aaaatgtttt catatagctc tttttatttt ttagctcgtt
    93241 tattatgaaa taggaaaaac atgtttttta gttacattac atatatttat aattatggat
    93301 aaatatatac taatcaataa tttagagtct aagataagct tataaatcat atatttagaa
    93361 tatatgggag gagtgataag attgaatgta aaatttaata ttaaaggtat aatttatgga
    93421 gttatagctc ttgtattcgt tataggggga tttatattca taccaagtat gtttgtagag
    93481 aaatctaaac ccatagatta tacagtatta caaagaaatt caataccaga aaagatatta
    93541 gatgtgatgg ataagtatac aaatgaagaa agagcattag cggctaaaat cgataacaaa
    93601 atatacatta tagtgactag aggaaataat aaatatggta tagaaatgga caaaatagaa
    93661 agtgtggttg aggaaggaaa ggatgttttg agagtcaaga taaagtataa agataaggaa
    93721 gattcttttc catacatagt tgttgaaaca aatatgagtg aacttccaga tagaatagaa
    93781 ttaaatgcga cgaaataaga aggtatttta taattaaata actgcatatt gtacaataaa
    93841 gtcatggttt ttattaatgt aagtaaattg tatatggttc ttattgttgt aaaagccatg
    93901 acttaaaatg cttataaagt aagatattaa cagtagtatt tattactata ttaaatgggg
    93961 tctggaaata cttaatgttc taattatttg gagtgataat tctagtttca gtaactatgt
    94021 agtctaattg tgcatcatga gtttcttttg gaatagaatc gaatatctgg aagtcaaatg
    94081 ctatgccaat agttatagca tcttttctta agttttctaa aaatctatca taaaatcctc
    94141 caccatatcc taatctatag caatgtatat catatgctac agctggtaca attacaacat
    94201 ctaaggcctt aatatcaatt gtaggtgatt tttcgttagg ttctcttatt ccatatgctc
    94261 caattctcaa tccctctttt aaatctgtta tttgagtagg gattaatgta tgattttctt
    94321 ttattgtgat gggacttgat actattttct ttagagacaa aagttttttg attaaattat
    94381 ctgtttgaac ttcattgtta aaatttagat aaagcattat attagttgca tttcttatat
    94441 cttccatttg aagtaatttt tcagttatta aatttgaatt actaagtaca aagtttgcac
    94501 tcttattttt tcttgattca ataacttttt ttctaaattc ttttttcata aaataattcc
    94561 tcccttaata tgttataatg tgtacagcaa ttgtatttaa tataaatttt agtataattt
    94621 attgtaataa agcaatatat ttgggtaaat gtaataaaaa taacagctag tcatataata
    94681 ataatagttt atgtaaaagg agatgtatct tgtgatttca aagaagaaag ctattttttt
    94741 aggggtgatt ttagtaatta taacagctat ggttacatca gcatttcagt tgacattggg
    94801 gaataaagtt gtaatatcga aagaactcta tgaagactat aaaaaatatg ataagttgtt
    94861 aggactagaa tctattataa aacaagattt ttataaaaaa gtatcagata ctgatttggt
    94921 aaatggagca gcaaaaggtc tatttctagg aacaaatgat aagtattctg gttattatac
    94981 taaagatgaa atggagaatc taattaatga tagtgaaggt tcttatgttg gtgtaggtat
    95041 gtatataggg gcatcaaaag atggtggctt agtagtagtt cccatgaaag attctccagc
    95101 agagaaagca ggtgtaaaat caggggataa attagtaaaa gtcaatggaa aatctgtctc
    95161 atataaaaat tcagatgaag ctgttcgtat gatgaagggt aaaaaaggga aaacagttga
    95221 actgactata ttaagagaag ataaacaatt gaactttaaa gtaaaaacag accagataat
    95281 tgagaagagt atagaaagta aagtaattga taatgattta ggatatatag aaattaccca
    95341 atttatatca agtacatata ctgactttga taaagcttta aaagaattaa aagcaaaaaa
    95401 tatcaaggga ttagtaatag accttagaaa taatcctggt ggaatgctag atatatgtaa
    95461 agaagttgct gatgagttaa ttggtgaagg aactatagta tatacaaaag ataataaggg
    95521 aaatactgag tacttgaaat ctgataaaga aaaattggga cttccaatag tagtgttaac
    95581 taatggagaa agtgcttctg ctgctgaaat attaacagct gcaatcgttg ataataaaga
    95641 aggtatttct gtagggacta caacttttgg taaagggttg gtacaatcag ttgtaagatt
    95701 gaaggatgga acaggataca agttaactac tgctcaatat tttacaccta atggagatta
    95761 tatcaatgaa aaaggcataa agcctactat tgaagaaaaa gatgaaaata aacagttaga
    95821 tgtagcgact aaatggctta gagaacagat tgataaataa agtttaattt ttataaactt
    95881 atattgtaaa ataaagaacc ttaataaaag gagtgtctca aaattaactt tttagtttat
    95941 gaggcactct tttgtgggtc tttaaaataa agtgtgtatt cttctaaaaa gtagtgataa
    96001 ttaaaatatt aaatatcact atatataagg aaggtgcaca ctttttatgt ttaacaaaaa
    96061 cgaaatatta aaaaaactta ttgaagaata tgatgttaaa acaactacag atattcaaga
    96121 tatgctaaaa gatttatttg caagtacaat tcatcaaatg ttagaagcgg agcttgacga
    96181 ccatttaggt tatgatagat atgacaataa gaataaaaat actaaaaact ctagaaatag
    96241 atatagaaat aaaaatgtta aatcagattt tggagaaata actttaaata ttccaagaga
    96301 tcgaaatgga gattttgaac caaaggtaat tagaaattat gaaaatgata tatcaggaat
    96361 agagaaccaa gtgattggaa tgtactcaaa aggtatgtct actcgagata tatcaagcca
    96421 ccttaagagt atttacggaa ttgatatatc tcattctcta atagctaaaa ttactgatag
    96481 agttctacct ttagctcatg aatggcaaag cagagctctt gatatggttt atccaattgt
    96541 atttatgggt gctatacatt ataaagttag aagtgaaggt agaataataa acaaagctgc
    96601 atatatagcc ataggtgtta acttagaagg tataa
//
LOCUS       DAEQJM010000009        96420 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.009, whole genome shotgun sequence.
ACCESSION   DAEQJM010000009 DAEQJM010000000
VERSION     DAEQJM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 96420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96420
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.009"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..995)
                     /gene="gap"
                     /locus_tag="KRQ43_000803"
     CDS             complement(<1..995)
                     /gene="gap"
                     /locus_tag="KRQ43_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH2741175.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYSDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNQKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVK"
     gene            complement(1632..2096)
                     /locus_tag="KRQ43_000804"
     CDS             complement(1632..2096)
                     /locus_tag="KRQ43_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HBH2741176.1"
                     /translation="MKKLVIILISIISVVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFAISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            complement(2420..3028)
                     /locus_tag="KRQ43_000805"
     CDS             complement(2420..3028)
                     /locus_tag="KRQ43_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH2741177.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            complement(3110..3811)
                     /locus_tag="KRQ43_000806"
     CDS             complement(3110..3811)
                     /locus_tag="KRQ43_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741178.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            4038..4304
                     /locus_tag="KRQ43_000807"
     CDS             4038..4304
                     /locus_tag="KRQ43_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBH2741179.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSMIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            complement(4407..4826)
                     /locus_tag="KRQ43_000808"
     CDS             complement(4407..4826)
                     /locus_tag="KRQ43_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBH2741180.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERIFNLKQEKRKAKHKGH"
     gene            complement(5093..5875)
                     /locus_tag="KRQ43_000809"
                     /pseudo
     CDS             complement(5093..5875)
                     /locus_tag="KRQ43_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(5940..6701)
                     /locus_tag="KRQ43_000810"
     CDS             complement(5940..6701)
                     /locus_tag="KRQ43_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH2741181.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLARILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNKKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            complement(7750..8562)
                     /locus_tag="KRQ43_000811"
     CDS             complement(7750..8562)
                     /locus_tag="KRQ43_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH2741182.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPVNYPNLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNDEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            complement(8932..9834)
                     /locus_tag="KRQ43_000812"
     CDS             complement(8932..9834)
                     /locus_tag="KRQ43_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH2741183.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDGQISFFD"
     gene            complement(9884..10345)
                     /locus_tag="KRQ43_000813"
     CDS             complement(9884..10345)
                     /locus_tag="KRQ43_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HBH2741184.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            complement(10397..10852)
                     /gene="def"
                     /locus_tag="KRQ43_000814"
     CDS             complement(10397..10852)
                     /gene="def"
                     /locus_tag="KRQ43_000814"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH2741185.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            complement(10824..11087)
                     /locus_tag="KRQ43_000815"
     CDS             complement(10824..11087)
                     /locus_tag="KRQ43_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741186.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            complement(11184..11900)
                     /locus_tag="KRQ43_000816"
     CDS             complement(11184..11900)
                     /locus_tag="KRQ43_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741187.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGTLAFIITMILLIFFSLTKISFLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYIYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            complement(11897..12574)
                     /locus_tag="KRQ43_000817"
     CDS             complement(11897..12574)
                     /locus_tag="KRQ43_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741188.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILISIIIIIYFITYYFICSSWK
                     KVGGVKL"
     gene            complement(12571..13416)
                     /locus_tag="KRQ43_000818"
     CDS             complement(12571..13416)
                     /locus_tag="KRQ43_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741189.1"
                     /translation="MIKVDDLSFSYTDRNFLQNINFEVEKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIKKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            complement(13530..14120)
                     /locus_tag="KRQ43_000819"
     CDS             complement(13530..14120)
                     /locus_tag="KRQ43_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2741190.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRVVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            14409..14642
                     /locus_tag="KRQ43_000820"
     CDS             14409..14642
                     /locus_tag="KRQ43_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBH2741191.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            complement(14873..17260)
                     /locus_tag="KRQ43_000821"
     CDS             complement(14873..17260)
                     /locus_tag="KRQ43_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HBH2741192.1"
                     /translation="MKKFTSKKVARFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SDTYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSVKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMDGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVSYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFNIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(17452..18207)
                     /locus_tag="KRQ43_000822"
     CDS             complement(17452..18207)
                     /locus_tag="KRQ43_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HBH2741193.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKNTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            complement(18232..19383)
                     /locus_tag="KRQ43_000823"
     CDS             complement(18232..19383)
                     /locus_tag="KRQ43_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH2741194.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLEPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            complement(19583..20323)
                     /locus_tag="KRQ43_000824"
     CDS             complement(19583..20323)
                     /locus_tag="KRQ43_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBH2741195.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            complement(20395..21384)
                     /locus_tag="KRQ43_000825"
     CDS             complement(20395..21384)
                     /locus_tag="KRQ43_000825"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBH2741196.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEVHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            21644..22897
                     /locus_tag="KRQ43_000826"
     CDS             21644..22897
                     /locus_tag="KRQ43_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBH2741197.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIGLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            22994..23218
                     /locus_tag="KRQ43_000827"
     CDS             22994..23218
                     /locus_tag="KRQ43_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH2741198.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(23434..24741)
                     /gene="grdB"
                     /locus_tag="KRQ43_000828"
     CDS             complement(23434..24741)
                     /gene="grdB"
                     /locus_tag="KRQ43_000828"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(23692..23694),aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH2741199.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVVTGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            complement(24827..26113)
                     /locus_tag="KRQ43_000829"
     CDS             complement(24827..26113)
                     /locus_tag="KRQ43_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH2741200.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            complement(26392..27714)
                     /locus_tag="KRQ43_000830"
     CDS             complement(26392..27714)
                     /locus_tag="KRQ43_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH2741201.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            complement(27714..29708)
                     /locus_tag="KRQ43_000831"
     CDS             complement(27714..29708)
                     /locus_tag="KRQ43_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH2741202.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIKNTFSENTN
                     KTSEIEIYNKILKINTFPVEYKKNNTEYIVVLIKDITNEKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            complement(29795..31042)
                     /locus_tag="KRQ43_000832"
     CDS             complement(29795..31042)
                     /locus_tag="KRQ43_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH2741203.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSSGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            31270..31815
                     /locus_tag="KRQ43_000833"
     CDS             31270..31815
                     /locus_tag="KRQ43_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2741204.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCIDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            31829..32515
                     /locus_tag="KRQ43_000834"
     CDS             31829..32515
                     /locus_tag="KRQ43_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBH2741205.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGNSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(32639..33259)
                     /locus_tag="KRQ43_000835"
     CDS             complement(32639..33259)
                     /locus_tag="KRQ43_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741206.1"
                     /translation="MNYNSNKNKYLLKDINLEDIFIDKNIVLKFLGYGNRKAPDTISE
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDIKMNDYMENCNM
                     MAGIALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(33249..34271)
                     /locus_tag="KRQ43_000836"
     CDS             complement(33249..34271)
                     /locus_tag="KRQ43_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HBH2741207.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEYIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRINYKELDR
                     IDIDEL"
     gene            complement(34272..34910)
                     /locus_tag="KRQ43_000837"
     CDS             complement(34272..34910)
                     /locus_tag="KRQ43_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH2741208.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            complement(35028..36179)
                     /locus_tag="KRQ43_000838"
     CDS             complement(35028..36179)
                     /locus_tag="KRQ43_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2741209.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDDDLDKMLELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TESLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            36601..37413
                     /locus_tag="KRQ43_000839"
     CDS             36601..37413
                     /locus_tag="KRQ43_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HBH2741210.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            complement(37502..37693)
                     /locus_tag="KRQ43_000840"
     CDS             complement(37502..37693)
                     /locus_tag="KRQ43_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741211.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            37998..38204
                     /locus_tag="KRQ43_000841"
     CDS             37998..38204
                     /locus_tag="KRQ43_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2741212.1"
                     /translation="MFKKKSGYTFTNFLNKVRVEKNKKYLLKKDLSILDVTVLIGFNS
                     QNYYSIIFKKFNNLTPIEYKNIYN"
     gene            38513..40132
                     /locus_tag="KRQ43_000842"
     CDS             38513..40132
                     /locus_tag="KRQ43_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH2741213.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGNCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            40506..40700
                     /locus_tag="KRQ43_000843"
     CDS             40506..40700
                     /locus_tag="KRQ43_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH2741214.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYEM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(41260..41583)
                     /locus_tag="KRQ43_000844"
     CDS             complement(41260..41583)
                     /locus_tag="KRQ43_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741215.1"
                     /translation="MATEIFTVKITPLEAQKMIKENIDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTEKTVIKATSTGSAIGVLKIDWGAGGNLLKRVKNIL
                     AEYII"
     gene            complement(41628..41882)
                     /locus_tag="KRQ43_000845"
     CDS             complement(41628..41882)
                     /locus_tag="KRQ43_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741216.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            complement(42146..42427)
                     /locus_tag="KRQ43_000846"
     CDS             complement(42146..42427)
                     /locus_tag="KRQ43_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741217.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            42740..43549
                     /locus_tag="KRQ43_000847"
     CDS             42740..43549
                     /locus_tag="KRQ43_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741218.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKEKL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEV
                     QNNKRPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            43592..43858
                     /locus_tag="KRQ43_000848"
     CDS             43592..43858
                     /locus_tag="KRQ43_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH2741219.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTDIEKPFWGEQCPVKSCCED
                     KNLIHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            44140..44904
                     /locus_tag="KRQ43_000849"
     CDS             44140..44904
                     /locus_tag="KRQ43_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH2741220.1"
                     /translation="MNNYLKFATYQLIGFTSSIPSLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            44967..45251
                     /locus_tag="KRQ43_000850"
     CDS             44967..45251
                     /locus_tag="KRQ43_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH2741221.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            45399..45941
                     /locus_tag="KRQ43_000851"
     CDS             45399..45941
                     /locus_tag="KRQ43_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HBH2741222.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDNKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(46104..47648)
                     /locus_tag="KRQ43_000852"
     CDS             complement(46104..47648)
                     /locus_tag="KRQ43_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020246462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBH2741223.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(47669..48748)
                     /locus_tag="KRQ43_000853"
     CDS             complement(47669..48748)
                     /locus_tag="KRQ43_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HBH2741224.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            complement(48802..50091)
                     /locus_tag="KRQ43_000854"
     CDS             complement(48802..50091)
                     /locus_tag="KRQ43_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH2741225.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     misc_binding    complement(50254..50465)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(50896..51327)
                     /locus_tag="KRQ43_000855"
     CDS             complement(50896..51327)
                     /locus_tag="KRQ43_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HBH2741226.1"
                     /translation="MAKVVSINISEKKGVIKVPVPCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
     gene            complement(51363..51833)
                     /gene="moaC"
                     /locus_tag="KRQ43_000856"
     CDS             complement(51363..51833)
                     /gene="moaC"
                     /locus_tag="KRQ43_000856"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBH2741227.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDYMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            complement(51837..52796)
                     /gene="moaA"
                     /locus_tag="KRQ43_000857"
     CDS             complement(51837..52796)
                     /gene="moaA"
                     /locus_tag="KRQ43_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBH2741228.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            complement(52843..53346)
                     /locus_tag="KRQ43_000858"
     CDS             complement(52843..53346)
                     /locus_tag="KRQ43_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HBH2741229.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            complement(53813..54151)
                     /locus_tag="KRQ43_000859"
     CDS             complement(53813..54151)
                     /locus_tag="KRQ43_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBH2741230.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            complement(54330..54701)
                     /locus_tag="KRQ43_000860"
     CDS             complement(54330..54701)
                     /locus_tag="KRQ43_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBH2741231.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            complement(54749..55357)
                     /locus_tag="KRQ43_000861"
     CDS             complement(54749..55357)
                     /locus_tag="KRQ43_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HBH2741232.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            complement(55382..56749)
                     /locus_tag="KRQ43_000862"
     CDS             complement(55382..56749)
                     /locus_tag="KRQ43_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBH2741233.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            complement(57266..58660)
                     /gene="yfcC"
                     /locus_tag="KRQ43_000863"
     CDS             complement(57266..58660)
                     /gene="yfcC"
                     /locus_tag="KRQ43_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBH2741234.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            complement(58848..59537)
                     /locus_tag="KRQ43_000864"
     CDS             complement(58848..59537)
                     /locus_tag="KRQ43_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH2741235.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            complement(59538..60641)
                     /gene="thiH"
                     /locus_tag="KRQ43_000865"
     CDS             complement(59538..60641)
                     /gene="thiH"
                     /locus_tag="KRQ43_000865"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBH2741236.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYEFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            complement(60658..61428)
                     /locus_tag="KRQ43_000866"
     CDS             complement(60658..61428)
                     /locus_tag="KRQ43_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBH2741237.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            complement(61491..62294)
                     /gene="thiF"
                     /locus_tag="KRQ43_000867"
     CDS             complement(61491..62294)
                     /gene="thiF"
                     /locus_tag="KRQ43_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HBH2741238.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            complement(62287..62481)
                     /gene="thiS"
                     /locus_tag="KRQ43_000868"
     CDS             complement(62287..62481)
                     /gene="thiS"
                     /locus_tag="KRQ43_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBH2741239.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            complement(62535..63836)
                     /gene="thiC"
                     /locus_tag="KRQ43_000869"
     CDS             complement(62535..63836)
                     /gene="thiC"
                     /locus_tag="KRQ43_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBH2741240.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     regulatory      complement(63978..64089)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(64177..66660)
                     /gene="recQ"
                     /locus_tag="KRQ43_000870"
     CDS             complement(64177..66660)
                     /gene="recQ"
                     /locus_tag="KRQ43_000870"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBH2741241.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDLKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GANILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVMLDSYLENLKNNIIAE"
     regulatory      66849..66970
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            67102..68205
                     /gene="ribD"
                     /locus_tag="KRQ43_000871"
     CDS             67102..68205
                     /gene="ribD"
                     /locus_tag="KRQ43_000871"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBH2741242.1"
                     /translation="MNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNIIGK
                     GYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKRVVI
                     STLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKSAVS
                     LDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQEKVS
                     HPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSKNNL
                     VDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPTFVS
                     GEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     gene            68239..68904
                     /locus_tag="KRQ43_000872"
     CDS             68239..68904
                     /locus_tag="KRQ43_000872"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBH2741243.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            68927..70120
                     /locus_tag="KRQ43_000873"
     CDS             68927..70120
                     /locus_tag="KRQ43_000873"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HBH2741244.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            70226..70687
                     /locus_tag="KRQ43_000874"
     CDS             70226..70687
                     /locus_tag="KRQ43_000874"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBH2741245.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGRYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(70907..72358)
                     /locus_tag="KRQ43_000875"
     CDS             complement(70907..72358)
                     /locus_tag="KRQ43_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH2741246.1"
                     /translation="MNFLNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            72828..74093
                     /locus_tag="KRQ43_000876"
     CDS             72828..74093
                     /locus_tag="KRQ43_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HBH2741247.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHVHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            74132..74587
                     /locus_tag="KRQ43_000877"
     CDS             74132..74587
                     /locus_tag="KRQ43_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741248.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(74731..75102)
                     /locus_tag="KRQ43_000878"
     CDS             complement(74731..75102)
                     /locus_tag="KRQ43_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HBH2741249.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(75105..75473)
                     /locus_tag="KRQ43_000879"
     CDS             complement(75105..75473)
                     /locus_tag="KRQ43_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH2741250.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            complement(75743..76621)
                     /locus_tag="KRQ43_000880"
     CDS             complement(75743..76621)
                     /locus_tag="KRQ43_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH2741251.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            complement(76638..76955)
                     /gene="trxA"
                     /locus_tag="KRQ43_000881"
     CDS             complement(76638..76955)
                     /gene="trxA"
                     /locus_tag="KRQ43_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH2741252.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            complement(77105..78337)
                     /locus_tag="KRQ43_000882"
     CDS             complement(77105..78337)
                     /locus_tag="KRQ43_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2741253.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            complement(78327..78998)
                     /locus_tag="KRQ43_000883"
     CDS             complement(78327..78998)
                     /locus_tag="KRQ43_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2741254.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            complement(79014..79850)
                     /locus_tag="KRQ43_000884"
     CDS             complement(79014..79850)
                     /locus_tag="KRQ43_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741255.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            complement(79876..80550)
                     /locus_tag="KRQ43_000885"
     CDS             complement(79876..80550)
                     /locus_tag="KRQ43_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH2741256.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKRKQNVKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            complement(80564..81292)
                     /locus_tag="KRQ43_000886"
     CDS             complement(80564..81292)
                     /locus_tag="KRQ43_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH2741257.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIKDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSGLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            complement(81419..82108)
                     /locus_tag="KRQ43_000887"
     CDS             complement(81419..82108)
                     /locus_tag="KRQ43_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH2741258.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLRVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMIGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            complement(82116..82679)
                     /locus_tag="KRQ43_000888"
     CDS             complement(82116..82679)
                     /locus_tag="KRQ43_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH2741259.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            complement(82681..83649)
                     /locus_tag="KRQ43_000889"
     CDS             complement(82681..83649)
                     /locus_tag="KRQ43_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBH2741260.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     regulatory      complement(83750..83793)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            84158..84787
                     /locus_tag="KRQ43_000890"
     CDS             84158..84787
                     /locus_tag="KRQ43_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2741261.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKAIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQSY"
     gene            84762..85166
                     /locus_tag="KRQ43_000891"
     CDS             84762..85166
                     /locus_tag="KRQ43_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBH2741262.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            85169..85642
                     /locus_tag="KRQ43_000892"
     CDS             85169..85642
                     /locus_tag="KRQ43_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH2741263.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNKIELSK
                     FDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPSS
                     LLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            86189..86854
                     /locus_tag="KRQ43_000893"
     CDS             86189..86854
                     /locus_tag="KRQ43_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBH2741264.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            86876..87808
                     /locus_tag="KRQ43_000894"
     CDS             86876..87808
                     /locus_tag="KRQ43_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBH2741265.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            87829..88470
                     /gene="pcp"
                     /locus_tag="KRQ43_000895"
     CDS             87829..88470
                     /gene="pcp"
                     /locus_tag="KRQ43_000895"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBH2741266.1"
                     /translation="MKILLTGFDPFGGELINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIK
                     GGFIHIPYTTSQVINKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(88589..88921)
                     /locus_tag="KRQ43_000896"
     CDS             complement(88589..88921)
                     /locus_tag="KRQ43_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741267.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            89187..89807
                     /locus_tag="KRQ43_000897"
     CDS             89187..89807
                     /locus_tag="KRQ43_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH2741268.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKEAI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            complement(90132..90956)
                     /locus_tag="KRQ43_000898"
     CDS             complement(90132..90956)
                     /locus_tag="KRQ43_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HBH2741269.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     TLFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(90967..92370)
                     /locus_tag="KRQ43_000899"
     CDS             complement(90967..92370)
                     /locus_tag="KRQ43_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2741270.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIREYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            complement(92374..93099)
                     /locus_tag="KRQ43_000900"
     CDS             complement(92374..93099)
                     /locus_tag="KRQ43_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2741271.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDVQNESKNLNKNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            complement(93211..93984)
                     /locus_tag="KRQ43_000901"
     CDS             complement(93211..93984)
                     /locus_tag="KRQ43_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741272.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFLGFLLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNEPIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVRYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            complement(93990..94877)
                     /locus_tag="KRQ43_000902"
     CDS             complement(93990..94877)
                     /locus_tag="KRQ43_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741273.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDANYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVFDEP
                     TAGIDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSGDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            complement(94891..95913)
                     /locus_tag="KRQ43_000903"
     CDS             complement(94891..95913)
                     /locus_tag="KRQ43_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741274.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETERYYID
                     KEKGCIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
BASE COUNT        32732 a        15740 c        10387 g        37561 t
ORIGIN      
        1 tattttacta agtcaacagt tcttgaagaa tatccccatt cattatcata ccaagaaact
       61 accttaacca tattgtcttc tataaccatt gtggatagag cgtctataat agatgatctt
      121 gaatctcctt tataatctat agaaacaagt ggcttgtcac aatatcctaa aacacctttt
      181 aattctcctt cagcagcatc ttttaacaca gagttaactt gctcagatgt aacgttttct
      241 ttaagttcgc acactaaatc aacaagtgaa actgttggtg ttggtactct aagtgaaaaa
      301 ccatttaatt ttccttctaa ttgtggtagt actcttgaca cagcttttgc tgctcctgta
      361 gtggtaggta ttatagattc agccgctgct cttgctcttc tcaaatcttt atggctttta
      421 tctaatattc tttgatcgtt agtatatgaa tgtactgtag tcattaaccc ttttactata
      481 ccaaattttt cgtccaatac tttagcaaaa ggagctagac aatttgtagt acaagatgca
      541 tttgaaatta tattgtgctt ttgattatca tattctttct cattaactcc gataactata
      601 gttatatctt cattttttcc tggagctgtt ataattactt tttttgctcc tgctttaata
      661 tgtttttctg ccttttctct ttgtgtaaat aatcctgttg attctattac tatatcaacc
      721 cccagttctt tccatggtaa ttcttctggg tcactatatc ttaatatttt tatctcttta
      781 gagtttacta ctagagtgtc ttcatccttt gcctctactt cacctctaaa agttccatag
      841 catgaatcat atgtaaataa atgtgccaaa gattctgttg ttgctcttgc atttatggct
      901 acaatttcta tattatctcc taattcttct tgagctattc ttaatacagc tcttcctatt
      961 cttccaaatc cgttcattcc taccttaatt ttcattatga aatgtctccc tccattacta
     1021 tgtttttaca tgattattgt acactaaata aatcatttgt tcaatacttt ttcttgatta
     1081 aataatcaaa ttccatgttt ttttattatc aaaagacaat tagtatatca tttttcttta
     1141 tttcacccct catttagtat gtacttttta gtgtaaataa gctgaaatca tttattttac
     1201 tcaatgtccc ttgggacata ttttgccatc ttttttttga atttttaaac tatacttatt
     1261 tttaaaaata atatatcttc aagaatctcc tctaatttaa aataataaaa acaaattttt
     1321 atttagttca aaaaatatat gattttttaa aatttgccac aattattatt tatatatcaa
     1381 aatataaata ataattagct tattgttaac taaattatgg aaatatactt aattgaaaac
     1441 ttaaatttat ttccttgtgt tatcaagatt tcatgcttac catttccaat atcatgctca
     1501 ccaacttttg atgtgcataa actatttcaa gtaaaaatgc acaacctatc ctttttgata
     1561 ggaaaaagca gtcaatcata aatatcaact gcttttatgt actgaatatc aagttataga
     1621 caagctggaa tttattttga gggtttttct ttctccttaa ctaaattgct ttcaaaagta
     1681 acctttacaa ctgcatgatt tattttaatt ccggtaaagc atatagcata ctctttctct
     1741 ttttgtatat tagaaagaga aattgcgaat gtatcattat caacgcttcc atgccatgta
     1801 ttactccata aagtttcatc tgttttattg tcctttattt ccacaatacc actatctcca
     1861 tccattttaa aagaaatctc tgtgtctaaa acatctatat cattagacac acaaaacaaa
     1921 cgtgcattaa caaatgggtc tgaagtatca taatttttat ctaagtccat ttcaatggtt
     1981 gtttgtcctg attctttgtt gtttaaatta ttatatttac tttcattgct ttttttacaa
     2041 gctgtcaagc taaccacact aatgatacta attaaaataa taactaattt tttcatagaa
     2101 tttatctcct ttacaatttc taatttttaa ccctacaaac tataatatta aactaatcta
     2161 ctattttaca tcaaattttt caatcattca gcctttacct tttctcattt taattgcaaa
     2221 tatgctaaat aattttggaa ttttaattat tgtagtatct taaattggtt tataacatat
     2281 tatgaaaatt taagagtcaa gtaacttatt taaaaataca caaaattata ctttattgta
     2341 taaaaaaaga gattataatt tatacaagta aaataaactt tattatttta ctcttctata
     2401 taacctcttt tctatatatc tattcaaata atttagctcc taaactcaca aacatttgta
     2461 aaatcaaaaa tgcttttgtg tctatcttat gattactttg taaaatctct tttgcatctt
     2521 cttgcgaaat taaaagcgct tcaatctctt catctggttc taaaaattca tctgttatat
     2581 caccatcaca tatacaataa acaaaggcaa cagattcatc actcattcca ggagataaat
     2641 aaactttatc aatactttta ttttttttaa tttctaaaag agtaagtcct gtttcttctc
     2701 taagttctct ttcaacagaa atatctatag actctccttc atcaacaaga cctgctggta
     2761 actcgtatat atatccatta ataggtactc taaattgtct tattaaaatt aattttttac
     2821 tacttttatg aagcccaact attacaactg catctacact atcttcttca ttcttcaaat
     2881 aaatattttt taattgctca ctactttttc ttgatgctac catccaaacc ttatcttcat
     2941 ctaatttgtt tttatactct atttcaaaaa gtcctataaa cttattttca atcattggat
     3001 ttacattctt tattatagtt tttttcaaat ttactacgac ctttcttttt taataccttt
     3061 ttaacatcat taagtaaata taatatctta acaagtattc aacaacttat tatatttcca
     3121 tttcaggatt atctttatct acaaaaccta ctttgatttc acaattaaat atttccttta
     3181 acaattttgc taattcttct cttgcactca ttaccttatc taaattagca tcagtaaaac
     3241 catctatagg aaaaaatata ttttttgagc tattagtaat ttttccttcc tctccttgtc
     3301 tccatatcca tcttctagtt tttaccatgt ctccaactga ataaattaat tctccttctt
     3361 ccattaattc aacatcagtt tctccaaatg gtacaaattt atcccctttt ttagaaaatc
     3421 taacatatac atcatcattt ctaaaatcca tatcatgagc acccattgga agtaaatatt
     3481 ttaaagaaat agagtttcct aaatctacaa taggatttat atgaggaagt ttcttattct
     3541 tagcaaccct tgttgtcatt gcttctatcg aactcataaa tttatttggg ttcatgccta
     3601 gacttctaaa tgcctctcta tatggtataa tttcttctga ttcctttact tttttatctt
     3661 tgaagtaatc ttctactcta tctatactta tatctaaaag gttgcttatt ctttctattt
     3721 ctttagtatt atctattcct tttgcaacta ctacaccaaa gcatacattt tctaatttat
     3781 caaaaacttc tttttctact ataaatttca ttttgcttta tcctcctgtt attttacatt
     3841 attttctaaa tagattttat cactttgtgt cttataaata taccccctat ttgctaattg
     3901 tttaattttt ttaaattttc caattaatat tatatttatt cttatcagat attttatatg
     3961 tactaattac aaatttaact ttccaaaaca aatatcttgt tttataatgt ataatatatt
     4021 tttatggagg caagactgtg aaaaatttta ttctaatata ttttatagtg attaattcta
     4081 ttgctttctt ttcaatgtac atagataaga aaagagcaat tagaaacgaa tggagaataa
     4141 aagaagctac tcttatgtct atagcagtaa ttggaggtag tataggttct atgattggaa
     4201 tgtattcttt tagacataaa actaaacaca ttaaatttac atttggtata ccatttatac
     4261 tatttttaca atttttatta gtatattttt atattttaaa gtaattgaaa tataaaacct
     4321 tattcttttc aataaattaa ggtgtataaa attaaaaact ttatacacct ttttctagca
     4381 attattaaaa agatatttaa ttaaaattaa tgacccttat gtttagcttt tctcttttct
     4441 tgtttcaaat taaatattct ttctttttct tcttcttttc tatttttagc taggtttttt
     4501 ctatcctgtt ttctttcttc atattgaagc ttaagagcat tttgagcctt agtccctata
     4561 gtttcttttt cttgttcctt ttttactttt ctctgcattc ttttgtatcc aatgttgtct
     4621 ttggtcacat ttttttctaa tttaatgcta ccaaaatcta atgagaaaaa tctttcaagt
     4681 ataaattcat acacttctac ttctttaggt tctgctccaa aaactaccct acatgcttca
     4741 tattttttac catcttgtct ttcaaatata cctacccaaa atggttcttc aaataagact
     4801 gttaattttc cactaatttt gtccatcgct agttcctcct taaattactt tctaaagaac
     4861 ggacaaccaa ggaggcaggt tactgacagc tattgctgcg tctggactac caaccagact
     4921 gtgtttttat ctttatagat taaatattat cttttttaat catgcttgtc aatcttagta
     4981 tcaacatcta tcatattgat ttaagtgaaa tcaagctttt taactctact ttattattgt
     5041 taacactaag aaaattaatt atttttcata ataaattagt tattatactt atttaaatat
     5101 caatctttat tgttccctgc ataaacaaga ctgcttcacc agaaattttt acagtattat
     5161 ccttcaacac ttcacactga attataccac cacgattaga aagttgagca gctaccattt
     5221 tgtgttttcc caacttttca gaccagtatg gaataaaatt acaatgtgat gaaccagtaa
     5281 cagggtcttc tgaatctaat tctggacaaa aatatcttga tacaaaatct gtattacttc
     5341 cttgtggtgt gattattata cctaaccagt ctgtcaattt acgcaattgt gcgtaattag
     5401 gtttataatt tataacttct tgttcactgt ttagcaataa gattaaatct cttgaagaat
     5461 agacagcact tggtacacag cctatcaaat tagcttgtta tggtgataac tctatttcaa
     5521 taggcattat ttctggaaat atcatttcat atagatttcc atttcgtgta acttcaagct
     5581 ttccactttg agtaaagaaa tctatccttt ttacattaac atcaataaaa tttgatatta
     5641 cataagctgc tgctaaagtt gcatgaccac ataaatcaat ttctgcttta ggagtaaacc
     5701 atcgtaattc ataatttcct ttacctttaa ctacaaatgc tgtttctggt aaattgtttt
     5761 cttctgctat tttctgcatt aactctaaag gtattattct gtcaagaaca caaactccag
     5821 caggatttcc tttaaatagt ttagttgcaa atgaatcaac tatgtagtat tccattattt
     5881 gacctctctt tccaacataa aatatacatc aatttacatt caataaaact ttaaatttct
     5941 tacatatatt ttttaatatt gctctgctca acaacttttt tacctaacaa tgtaattgct
     6001 ttttttgcac aattatttac acaacgataa cacattgtac attgcccatt tgcaacaatc
     6061 atacaatttt taattactag attcttcatt ggacataaat taacacattt accacataca
     6121 atacattcct cagtattaat ttttagttta tctgtataca tatttgtttt attgataaaa
     6181 tacaatcgtt gtccaaataa ccctacaata tgactcaaaa aacctaaccc ttcttttggt
     6241 ggtgacccat gtttcagttt tttagcagct ttagttactt tcttttctgc ttttattaca
     6301 agctttttat tatactctaa agaatgtttt aatacctttt catctcctat actatctggc
     6361 atcttcacat gtaatccacc aacagttata gcaccgtatt tttttaatat tctagctaac
     6421 acaccagagc catctccact aaatagagcc atagttgcaa taataaaaac acgtttacca
     6481 ttccacaaag ttgaatgatt tattataaaa tctttcaata tttttggcac attactatat
     6541 tgcacaggat aactaaaaat aatattctca tgattattga tgtgctgtaa aagttcatta
     6601 tcttcaatag aataagaatt tgctgttata tcatattctt gtaaaaattt ttctacacag
     6661 tatcttgaat ttcctgttcc actaaaatat attcctatca tagtacttct cctaatagct
     6721 aagattatat agctctattc ttaaaattct gactttttat attatctaaa ttaagtagtt
     6781 tatttaaata atataaactt aattcaacaa gttacctact gaacctccca tgactaaagt
     6841 catagggttc ctgcttgata gaattttaca taatcaattt actaaatact tgtctaattc
     6901 tttttttatc attttaaata tacattttaa taatattagt aagctatact tccttaagca
     6961 tatattttcc ctaaagtaaa actattgatg attattccat tatataacct aattataaat
     7021 ttagtaagtt catcacatac tataccctta attctcaatt ataaagttcc ctaaaaaata
     7081 tttgaaaatt taactatgaa aagatttcct attgcctaat atgtataagt aaggagtact
     7141 atatagtact ccttatattg tactcttata acattgatac cttaatatta ttttaatctt
     7201 aatcattatt gatttgattt aaaattataa ataggttcca atattttaat tatgtcaact
     7261 atatctctta tagttttaat aatctcatca attggtttat gtgcttgttg cactttatca
     7321 atagtattaa ttaaatccat ttacacatct agcacctgta tggcaattta gcattatcct
     7381 tatcttatac tttgttgtaa attcttgatt acataattct attatctaac ttatagctgt
     7441 gcaatctaca ttatctgtaa atatctttgc tttatatatt ttccctgaac ctctaacatt
     7501 aatataacag cctttttgct atacactttt aactatatac ttaattttaa taacattact
     7561 tgtttataaa aatatactat agataaattt cacataaaaa taataattca agtattgatt
     7621 tttatataag aaaatttgta atgtactaaa aataacataa aagtttccat ttttcaatat
     7681 gtaagctttt cttatgttat tttattgtta aaggtttcaa gtttttattt attcatttta
     7741 aaaaaattat tatttttgta aaactaatcc catagtcata ctatcgtcag aatatgcttc
     7801 acccttaaca ttactaaaaa actcaacaga cttaaatcca atattttcaa cttctaataa
     7861 gaaactttct tttgaaaaat agtgattcca aacataaaat acattttcat ctttttcggt
     7921 tattacaaga gtttgttcta atgtattata atcattgtat ttacaattat cttgtagaca
     7981 catatatttt tcattactcc aaaatcctcc atcttcattt atttcccaat atttaatttc
     8041 ctcaaaatta ttgtatttat ttattgtaaa tacatctaat attaattttc ctccaggttt
     8101 taaactatca taaatttttt ccattaataa ccttctattt tcagttgaca aagctccata
     8161 atcacaataa attaaagtag ccaaatcaaa ttcatcatta tagttcatat ttaaataact
     8221 ttgaaacaag taatttatgt ttaaattagt ctccttattt ctattttgtg catagttaat
     8281 agaacgtttt gagaaatcaa ttccagttac cttataacct ttttgtgcaa atttctctgc
     8341 atataaacct ggaccacaac ctaaatcaag taaattagga taattaactg gatttgcaac
     8401 tgtaactatc caatttacag aatcctcgat aaagttaaaa tttctacttg ctccttcaaa
     8461 attagtgtct aaatgtgctt ttaataattg ttttgaaata tactcatcat cccaaaaatt
     8521 aatttcactt tgtttataaa gctctggtct ttctaaatac atacataatt tgtttaacaa
     8581 aacataccac tccttaaaat ttatttttaa aataaaaaaa ccacagagtt tactctgtgg
     8641 tttaacttca aaaagatgag tttaaataag agtaaaatag aaccaaatat ttttaagcac
     8701 aacaataaaa ctatagcttt actttgtttg cttattaaat ttgattttat tcactctttt
     8761 ccagcaatac ttatatcaac gattttatga tatcaaatat caccgaacaa catcatcctt
     8821 tcatattttt attttatgaa tcaattatat atttaaattt tatatttgtc aataaatttt
     8881 aattttaata aattttaatc atcatagtaa aaaaaaattt tttatataaa actaatcaaa
     8941 aaaagatatc tgtccatctc ctgagttttt taacttttcc ttcattattt tagagtaact
     9001 gcttgataga gaatatttat atctaagttc attaaccatt ttatacaatt gatttttata
     9061 ctccctatta agtgaacctg cactatatag tattgataat ttatcaaata attcaggaaa
     9121 ctctttttta acaaagtcaa aaaaaacacc tctagttata ccccttaagt ataaagtccc
     9181 aggtaaaaca taatgtacat tacattcttt tgcatgtcta aatagcgaat ttatattatc
     9241 aaaatcatct gtaatatatg gtataattgg cataatatgt agaccaactg atgcgttagt
     9301 ttttctaaat tcttttaaca ttttaaatcg tctcattgaa tccacaccat ttggctcaat
     9361 aagcctttgt gtatcttcat ttactgtggt aattgtagat gctacattga tatatgtaat
     9421 cctagatagc ttatcaatta aatcgtaatc tcttaaaatt aaatctgact ttgtagaaat
     9481 aatagctggt gtcttgtatt ttatcagcag gtttaatatt tctggcataa ttttatagtc
     9541 agcttctatt ggttgataac tatctgtaac tcctcctata ttgattactt ctttcttcca
     9601 tttactgctt ttaagttgtc tctcaagttt ttctactata tttgttttta cataaatctc
     9661 ttcaaaataa ttattggagt taatgtactt atgagagtaa atagcataac aatatttaca
     9721 tccatgctca catccacgat aaatatttaa atcccattta tatggcatac tcctttttaa
     9781 tttattacaa gctatttcac aatttattgg aatatatttt attttattat acaaataatc
     9841 acctctttat atacaataat actataatgt taatctatag taattaaaac atgatatttc
     9901 cagaccacaa ttcataatct ttactatatt tacaaagtaa tatattccat tcatttattg
     9961 gtattcctcc acatgttgct ttttcttcta aattatataa gcattgcttt aaatacattt
    10021 tattatgcca atcatcatat aaattttcta aatttaaact atgttcatta gatatatcat
    10081 ttgcaaaatt tctatttttc cattttaata tacttgtata tttaagttca ttaggtttat
    10141 aatttctttt taacatttca tcatgtacaa tttttgtata aaatttaaat tcatctatac
    10201 tataattcaa tactttattc actaatagat ggtttggagt acctttttta tctatagaac
    10261 cttttatagc aagtagctct ctccattgac ttactaattg atttttaggt aatacatcaa
    10321 ttaaatcctt atgccataat ctcataattt aactccttac tataaaatat tttataaatt
    10381 caataaccaa tctatcttac aattttacat gttcaataat tttatctgta aaaactatac
    10441 catttaaatg gtctatctca tgacaaagac attttgccat aaaacctgaa cctttaattt
    10501 ctattttctc accgtattcg tttagagctt gcactgtaac tttttttggt ctttttaatt
    10561 taccccatac ttctggaaaa cttaaacatc cttcaacaac aatttgttcc ccttcttgtt
    10621 taataatttc aggattaaca agcttaataa gtccttctcc taaatctata acaactaatc
    10681 gctttaatac tcctacttgg catgcagcta atcctcctcc atttggagta ttgtacatgg
    10741 tctctgccat gtcatttaat atttctctta tcttattatc tacgttttct acatacttac
    10801 tcttttttct taaaatttca tcatcaaatg ttcttatctt tcttatagcc ataatattct
    10861 cccctactta tctgtgctct tgattttctt tcactttctt caaataaaaa tacactttca
    10921 attggttcat taaaaattct tgaaatatca tatgccaacc atattgaagg ttcattttta
    10981 ccagtttcta tagcatttat agcctgtcta gatgttccaa ctaatcttcc tagttgttct
    11041 tgtgtcaatc ctaatttttc tcttaatatc tttattttat ttttcatatt tgctccattc
    11101 atgtaaggtt aactttacat cttaaatgta acatttttca acattactgt caagtcaacc
    11161 ttacatttat atattaaatt ttcttattta actatttttt tactaaactt tttaaataat
    11221 aataaaatcc atattaatga tataacaatt gaaataaaca tatagatata attatcttcc
    11281 ttaaatgcct tcgatatcca aaaagttggt aagaagaaca gaatatattg tgctttattt
    11341 aaaataaaaa atggtgctaa aatacccatc ataaaaacac ctgagaattt cgtaattacc
    11401 attccttcta gtttatttga tgataaagaa atcactagta ttgatataat aactccttgt
    11461 aataaaacta ataaagaaat tgataagttt aacaagaaag aaattttagt tagagaaaaa
    11521 aagataagta gaatcatagt aataataaat gctaaggtac ctggtattcc aaatcgtgaa
    11581 ataagataac cagttttacc aagcggagtt actattaaat atcttgaaat gctgtcatca
    11641 atttctccca atatgaccat tgtagaagca aaaaagaaca taaaaggtgt aataaaagct
    11701 aaaagtaaat caaacatcaa gaaatacggc tctaaattta attgataata aaacttgtta
    11761 agtgatatat tctgtattaa tggtattcca aattttataa atactccaca taatattgga
    11821 gaaacacata ctataaaaag catagcatct ctcttaattt gttcaaactc ttgtttaaac
    11881 gcatttataa tctttatcat agttttactc cacctacctt tttccaactg ctacaaataa
    11941 aataataagt tataaaataa attattatta taattgatat taaaatatta atcattataa
    12001 aatttttatc tccactaata agagaaatac atatattaaa agggtacaaa tttgcatatg
    12061 attttgtgtc aagaagtaca ttgagtattg gtggaataaa gcatataatc tcaataggaa
    12121 tacttaaaac aataaactga ttcaaactag atgctttact tgcaagtatc aatccaagca
    12181 aagaaaatat aatagaagaa aaaaaggtac ctatagttga tattataata ttatctaaat
    12241 ttaatgtaat agcaataaac atagctacaa tactagatat tactcctaat gaaattacct
    12301 ttgataaaat atactcagat acttttactg gagatacagc taaggaattt aaaacccttt
    12361 gacttttctc aagaagtaca atagctccca taaaaaacaa tcccattgct gctgggtcag
    12421 aataaatcat aattatagct attttttctc tcataaaagt tggaaataca ttgataatac
    12481 aaatatatat aatacttaaa aaaagatata aaaaataaaa accatactta aattgaaact
    12541 ttatatctcc taaaataaga ttttttagcc tcattgtaaa ttcctccctg ttatctcaat
    12601 aaaaatatca tttaatgttg gttcactact atgtattgat aaaagtttat ttttcttaat
    12661 aagcatattc aaatttttat cattagcagt attgttcaga aaacattcag aagttttttc
    12721 tccattatca aagtaagtat atctaacttt aatagctcct tttgacataa taagattatg
    12781 tggtgtatct aaagcagata ttttaccatt tacaatgaac gctactctgt cacaaagctc
    12841 cgttgcatct aacatgttat gagttgttaa aataatagtt ttacctttag atttttctga
    12901 taaaattata tctttcataa ccttgctatt tgacgggtca agaccacttg ttggttcatc
    12961 taaaaataaa atatctggat tatgtaataa agcttttata aaatttaatc gagatttcat
    13021 accttttgaa tactcagata cccttttatt tgcttcattt tctagtccta ctgattttaa
    13081 taactcatca atagatagta gttttttaga atatagagac ccaaaatatt ttaaattttc
    13141 tattgcagtc aacttttcat ataaactagg aaattcaaaa tcaactccta tattttcata
    13201 aaatttattt gagtgtcttt tactctctac tccatttaca atgacacttc ctccataatt
    13261 agttatcatt ccaattagaa tcttttgtaa tgtagatttt cctgcacctg atggtcctaa
    13321 aaatcctagt atttcccctt tttctacttc aaagttaata ttttgtaaaa aatttctatc
    13381 tgtataacta aatgataaat catcaacttt aatcattcaa tatcaccctt tcaaattttt
    13441 gactattttg actatatggt caataaaata taattttttt gtttgttaat aatttttaat
    13501 aaaagttatt agcaaacaaa atttaaattc tattccataa gttgtataac taatccgttt
    13561 atcattaatc ttaaagcatc ttcaaaacaa ttacttccaa cctcgcgctt atatagcatg
    13621 gtaagaaaaa ctactctaaa tgctccacta aagctttcta tgtctttatt ttttgcattt
    13681 ggtatgcaag atataatctc tccaatttca aagtcatcat gtctaaagtg ttcttcaatt
    13741 atagaatctg gtaactttct caccaatatc tcaaattctc catttatcat gagatttaaa
    13801 attgaagtac tatcaaccat cctatagaat ttcataaata tatctgtcaa ttgttcacat
    13861 gtaatacttt catctactct atttatctca tataagattt ctttttgtat agagtcatgt
    13921 atatctctca atacctcaaa aaagagcaat tcttttgatt gaaaaaatag ataaaaagtt
    13981 ccttttggta tttttacccg ttttacaagc tcatcaacag tagtttttct aataccatat
    14041 tgctccatac acaatcttgc ttcttcttta agtcttttta ttatatactc tctttcttta
    14101 tcagaatacg atttaggcat ctttttcctc cagtttgact aaaataattt atatagtcaa
    14161 tataatactt tttctatcta atgtcaatag tattattagt atatttaaaa ataagcttaa
    14221 aaactttcga aaattctgaa ttttatatag cattttttat tatctagtgt tataattaag
    14281 atataaataa tatattattc taattttcat atctatttgc ttatttttta acttagtttc
    14341 taatagaagt actcatattt atctttttaa aagtttcaac tttaataaaa aataaaggag
    14401 ttgattttat ggctactact acaaaaaacc gtttttacga ttatgttcaa gaaaacttaa
    14461 ataaatatgt tgaagtacat tcttacttta gcagttgtcc tctatatggt gaaattatag
    14521 aagcagatag cttatcaatt acactttgct caagatatat agatgaatct aatccaactt
    14581 taaatgaaac ttacacatta tatttaccat taagttcaat aatatctatt agaacactat
    14641 aaaaagttaa ttaaatatgg gttatttata tataaaatat aagattttct atatttctat
    14701 atatagtaac ccttttttat gtttttaaac ttatactaca taaatttaaa gctgaaaaca
    14761 aaactttaca atcattgatt atcttattta tcaataattt aaagtaatta ttttcagctt
    14821 ttattaagat aagttactaa tacacactaa tatatgttaa tacttaagta ctctatttag
    14881 cactttttaa ttttactaac tctttaaatg catttttatt tgctcctcca ccaacttgag
    14941 ttactttttc taaagtctta tttttaagaa cttctttttg gctatcagct aatttatcac
    15001 caactaaaat tactggtgac ccagtttttg ctcctaaagg accaactgcc aatccatcta
    15061 ttaaatcatt ttgattcttg attccatttt taactacaaa tgcatttttt aaagtatctt
    15121 ttttataaaa attatctatt atctttgaat tagtttcgtc tctactacta ccagataatc
    15181 tagttggatt ttttaactta ctttctagat tgtttgatag ggatgctgtt cctccaataa
    15241 tataagattt ctctatattt aatgaattta gaaattcatc agctccttgc aattcgctct
    15301 tttcatttgc aagtatgatt ggtatgttat tttctgctgc agcagcacct acactaattg
    15361 catcagctaa tcctttcact ccatttacaa ctgctatttg agatacattt tttataccat
    15421 ttaacttttg agctaataat aaacttgtct tgtatctatc acttcctgat attctctcta
    15481 tcgatatatt taagcttttt aattgttgtt caatttcttt acttatagaa ttttctccgc
    15541 ctattaggta tactttctta gcacctaatc tctgtatctc agctttagtt tttgaattta
    15601 aagcttcttt ttgtgtcaat aatattggtg aatttatagc agatgtaaaa ggagttgctg
    15661 ccaatgcatc tactattgaa ctgccattta ctaaaactac attttctgaa gaattgaaac
    15721 cattttgact aactttgata gcagtttcat atctatcact accaattaaa gactcattcg
    15781 ggatactctc accagaagac ttttctgtaa cagcttttat agtaaaatta cacggataga
    15841 agttactatc tctatttata tcaaagaatt ttccagtatt atctatgata taactttcac
    15901 ctaaattagc ttttgcttta aatgtatcat atcctggtac atttgactca gaacctatag
    15961 ttgactctcc atttttcccc tctatactga ctacaattgc accctttcct tctggtatat
    16021 taaaagaatc aattggaact gttatgtatc ctgaatattg ggcagtacct tcttttaatt
    16081 ttttcatatt gttttcttga ggtataccat ttactactgg agcataagat acttcatact
    16141 tagctcctat actttcagtt aagaacatta cagattttag agtttcatcg cctctattga
    16201 aatcaaatac atttgcagct gttatctttt ttgaaattaa aggtacaata cttgcatagt
    16261 catgttgata catcttctca tcatcatttg gttttttacc acctttgatt gaaaaattat
    16321 ctatatcaga cataagtgtc ttgtcttcat aagatatcca gaaatatcca ccctcagaat
    16381 tataatctcc ccagctattt tttattaacc aagcaccatt ttttgatggt ctaatatttg
    16441 cattaaaatt atctttagaa tagttatcat cccaacccac aattgaaata gcatgatttg
    16501 tattaaaact ttttgttgga caataatatg aattttggtc atcactttga tatttaatat
    16561 cttcataata accagatgtt actgctccat actgtaatat agcatttttt gtagaattta
    16621 tgtcattact tacacacaca gcatctgtca cattaaaaac agtaggtgct gtattcatat
    16681 tagttggttt ttttgctcct tgtgctttag atactctacc attgtatggg atatcttttt
    16741 ctaatttagg acctgaccaa gatgttaaat atcccatagc ttcataattt aaagcaccat
    16801 ccatatcatt tacagaccat ccatattcac catctgaagc ccaccatctt aagtgttctt
    16861 ctgataaatc gtagtctcca taattattta acttcaagaa actttccaag gttgccattg
    16921 cagcaaaatc ccagcatatt cctaaatcct cttgattttt tactgatgtc ataagaccta
    16981 attttctagg gtcataagat gttggagctg ttcttccttt actttgaatt tgagtacctt
    17041 ctaactgata tggatttggt ataattccat tatatttttc tgtacgtcca tttttagcat
    17101 catttagata ttgtttataa gtatcactgt attctgcttt ttttatctga ttcaatgtat
    17161 tgctattgtc agctgacaca ggaattgttg acattactaa aatagatatt aaaaacagtg
    17221 caacaaacct tgctactttt tttgaagtaa attttttcac gctttctccc ccttattttg
    17281 agctaatttt taaaattcta atgttatata tgactaaata tcaagtattt acaaatatac
    17341 aatcatttaa atcaattata ccaaagtttt cctttataaa taaacaaaat aaaataaaaa
    17401 actgaactta tttatgataa attcagcttt tcattttctt tttatatgtt tttatctaaa
    17461 tcctattaca gcagctccta aagctcctat tatttgagta tcttctgcaa taaaaatttt
    17521 tttacccagt atttcttcta tcatttttac tagttcttta ctttttgcaa gccctccagt
    17581 aaatgcaact tcatctatta cctcacctct tgctaacatt gaggtggatt tatttgcaat
    17641 agatttaagt atccctgctg ctacctctcc agtagaaatg ttttgagcta gaagacttac
    17701 aatttcagac tcagcaaaaa ctgtacacat actagatata ttaactggtt catatccttt
    17761 agctaatgta tctatacttt caatatcgct tcctaaaagg ttagaagtaa tctctaaaaa
    17821 tcgaccagtt cctgcagcac acttatcatt cattataaag ttaaatacat ttccatctct
    17881 atctaaattt ataactttac tatcttgacc acctacatct aaaatagtcc ttatgttctt
    17941 gtttaaaaag taaatacctc tagtatgaca agttatttct gttactttct tatcagcaaa
    18001 atccattact ccccttccat aacctgtacc taccaccttt tttatatctt ttttgtcaat
    18061 ttcactactt agcaactcat agacctgttt agatgtattt ttagggctcc atccagttgg
    18121 tataattatt ttcttaataa ttttttcacc atcaaatagc acaccctttg ttgccactga
    18181 ccctgagtca actcctatac taaacatagt tcctcctact tttatttatt cctacaacat
    18241 ctctacaaac gcttcaaatc tagttcttaa ttgttcagta tctgattttg aataatcagt
    18301 ttcaagagac ataaatggct tatttttttc ttttgtaaca aattctctta ttctataact
    18361 ttctatatta aatgtatgac atgcttgtaa aactacatct attacagcat ctacattata
    18421 ttcatctatt attctatcta ataattcaat acgattgtca ttattcatca tacaagaaca
    18481 acctatattt atatattttt gtgttaaagc atcatataca tcttctattt cttcatcaac
    18541 caataaatcg tttgatctaa tagctccaca aagttcatat gcaacgactg atgcccctgc
    18601 atcttctaaa gttttaacta ttttttcgct tattccacca ataggagaac ctgttatcaa
    18661 tattcttggc ttatcttttt gaacaggaca ttcacctttt tcatatcttt ctttcatatc
    18721 atctataact tttcttaaag aatgtttaag ttctgcacgg tcaaatttaa aacctgcttg
    18781 atataaaaca ttatgtaact caaggcctgt aagtgcagat ggttctaatt taccaagtgc
    18841 ataaaactct tttaaaagtt ctctttcttc atttttatct tttatagcag ttcttatatc
    18901 ttcttcagtt atagttacac ctaaagattt ctcaacctct tcttttaatc ttatcatttc
    18961 atctttccaa agtttatagg caaattctcc ttttgaagta tttggcaaat gcattacata
    19021 tgttggctta acttttgcaa gttcttcata catttttttc ttaccatcac aagtggtttc
    19081 tcctatcaac aaatcagaaa aatagaaata aggacaggtg tctgttattg catgtccata
    19141 gcttgattta attaaaggac aaagatttct tggaagcacc ctttctgcat caggtattgg
    19201 ctcttcacta acaccgcata cacctactac agttgctcca gctgccattg gaatttcaac
    19261 tggagtaaat gtacagaaaa ctccaaccat ctttttccca ctttccttaa gttcctttgc
    19321 atttataaat cccttttgtc tagcttcatt gaagctatca aattgttttg gcaaatttgt
    19381 catgaaaata ttcctcccaa ttacttctct tcgtaattca atttgtatct taagcaataa
    19441 aaactaaatt tttccattaa aatacaaacc tctacattag attctatcat gctttacctt
    19501 ttatccataa ttgtttttat caatgcaaaa ttagatacat atagatatat tgtataacta
    19561 attttttatg ttataatttc tcttataact taagctctcg aatcctcaat ctataagcag
    19621 acacagcagt ttcacataat ttatcaatta attttccatt cacataaaat cctacaaatg
    19681 ctcctattcc aggcattagt tgtaaaaact tagctaaatc taaataatct ctatactctt
    19741 gttgaaatgt tctccaatca aaatcattga tgtcttctgg tagactattt acatattcat
    19801 cccagttatt catcaattta aaagttttgt ttatatgctg ttgactagaa aaagccaact
    19861 gtaatatgtt taatatataa atcctttctc tataatcttt aacatcatat ccatatattg
    19921 aagctacatc atataaaaat ttcactttaa tacctaaaag caaaggaaaa tcagataaac
    19981 ctaagaggat tcctcctgcc cctgttcctg ccccttcaat cattgctgtg gtcttgtaag
    20041 ttttagcttt ttctaaaact aatttttctc tttcttctaa tgacatattt ctaagtggtg
    20101 gctttgtagc atatttatat ccaaacagta cggtttttgt cattactttt atagaagaag
    20161 taattatttc atgatattta tctggcaata ctccattaaa tttattctgt ataccctttg
    20221 atgctttgtc aaatatagaa ggtttcttta atatattttt cttccattct tcaagttctt
    20281 ttttgactag tttaatataa acaacatctt cataatcttt cacatttttt ctcctaatac
    20341 aatgtatttt tgtcaattta atagcttaat ttaaagttta aatattttta tctattaaat
    20401 taaactattc aaatactctt tagtttcttt atctgcaaaa ctagcttcta ctgcatttct
    20461 ataaataatt ttatagtctt ctaatcctag tttaaaagta tcaaatataa catttagttc
    20521 tgaacttaaa tttatatctg atacagttct attatcagta tttatactta catgtaaatt
    20581 atctttataa aaagtataaa atggatgtac ctcataagaa tctactgtct tagtttgtac
    20641 attactagtt ggacataatt caagcaatat ttttttatct ttaactaaat tatacgcctt
    20701 tttatggtct ttaattttta ccccatgacc aatcctatcc gcctttaaaa tatttatagc
    20761 atccaataca ttttctccac ttgcagcttc tcctgcatgt attgtaactt tatatccata
    20821 ttctcttgct aatttaaaaa catctttata ttccttacaa aatccctctt tctctggacc
    20881 acacaagtct actgctacaa cacctttatt tacaaatgat ttcccttctt caattactaa
    20941 taatgcctct tttgaggtca ttgttctcat acaacctaat attaaattgc cttttatatc
    21001 ataaatactt tcagcttctc taattccttc aattataccc tcaattatat ttttaacact
    21061 catacctttt tgggtgtgaa gtaatggtgc aaatctaatt tcaatatatt ttacattttc
    21121 tctacttgca tcttccaaaa gttcaaaagt aattcttttt aaattttcct tagattgcat
    21181 tacttttaag ggtaaatcaa atttttctaa atattcatct agtgaagtac aattaaaaga
    21241 aacctttgct aattttttta tttcatccat attatttgaa ggtaaatcta ttttctcttt
    21301 aatagctata tcaagcatgg tttctactct aacacttcca tctaagtggc aatgtaaatc
    21361 tatcttaggt aaattttcaa acattttatc ctcctactgt acttataaat aatactatca
    21421 acagattttt aagtcttatt tctattatat caatatacta cggtttttca ttctaaaaaa
    21481 gtcacatctc attaaaatat tttaatttaa tttatgacta tctaattata tatactgatt
    21541 ctttttaata tacatttatt aatatacatt tgataataaa atttcaatac ataagaattt
    21601 aagttatata attaaaactt tgaattacaa aggaggactt attttgatta ccttaagttt
    21661 tgatatagtg caaaccttga cactatctat attcttcttt ttaattggta atttattgaa
    21721 gaataaagtt aactttttaa ataatttctg tatacctgca ccagtaatag gaggtctatt
    21781 attttgtttt ctaaatttat tttttaaata ttttaatata gcagatatat ctataagtgg
    21841 aaatttaatg ccaaatttta taaccttctt ttttacaact ataggacttg aaataagcat
    21901 aaatcttata aagaaaggtg gtagtgtatt atttagatat tggattttgt gtggagtatt
    21961 ggcattttgt caaaatatat tagctattac aatatcaaag attataaaac ttgaacctct
    22021 tttagggctt atgtgtggaa atgtatctat ggaaggtggt catggttatt ctgctgcatt
    22081 tggacttaca atagaaaatc tcggtataga aggagcagtt ggggttggat tatctgctgc
    22141 aacaatagga cttattatgg gtggtatatt gggatgtcct gtagctaaat ttctaataaa
    22201 taaatataaa ttaaaaccat catcaaatat aggcttgtcg attcctagat ataatagaaa
    22261 tctaaagaga tttggaagta aattttttag aaataagaat aggataaaaa ataataactt
    22321 ctccgaaaca ataacaccat ctgtattttt ggaacaggtt cttctcatat ttatttgtat
    22381 aaatacagga gaaattataa gtagatgctt ctatataacg tttaatatac tattaccctc
    22441 tgttgtaact tgtatgtttt cagctgttat ttttagaaat ttaaatgata agataaatat
    22501 attagaatta aattttaaac ttatagattt tttaaaagaa ctttcattgg gaattttttt
    22561 aactttatca cttatgaata tagatttatt tgaattatct acattattac ctcctattct
    22621 cttaatagta acttttcaag taatctttat aatcctattt tcaatattta tttgctttag
    22681 agtacttgga aaagattttg attctgccat cataataagt ggtttgattg gacatggaat
    22741 aggagctact ccgaacgctt tggcaaatat gagttctttg acacaaaaat atggtgattc
    22801 tccaaaagcc tttttggttg taccattagt aagtggtttt ttgctagatg ctattagtat
    22861 cccatgtata ctatttttta taaacatact aacttagtat gtttattttt tgttatatat
    22921 tgacaattta ctctttttgt tatatattat aaatataaag tttgataatg attttcatta
    22981 ggaggtgtta ataatgactg tttacaactt aaaacttgga caaaagggaa ttatagacaa
    23041 tatagctgga aatgaaaaac ttatgaagag acttctagcc ttaggactaa tagatggcac
    23101 tgaagttgaa gtgaaaaaga tagctcctct taatgaccct atagtgatta gatttagagg
    23161 gtttgactta gctattagaa aatctgatgc aaaaaatata aatttaaaaa ataattaata
    23221 tataataaaa agagatttta aaatctcttt ttttgtttat gtataatctt ctatttattt
    23281 ttttcattct ttatacttta attggctgtt ttactataaa tatttttatt acttaattgc
    23341 tttcttcatt ccatccatag caaaaagata tcataaaata attttcaaaa actattttat
    23401 gatatctttt tttatttcta tattatattt ttattattca aatactgttt gttcttctat
    23461 atcctctgtt agtgcattta aagcttttaa aactatattc tttctaattt ttttactttc
    23521 ctcttctcct aacataggat ttccaagtgg atatggtatc cctactgctg gaacaattct
    23581 attagctcct attgtaagtg atattggtac tactgtacat atatgaacaa ctgctatacc
    23641 agctctctca atctctttta ccatcgttgc tccacaacga gtacaagtac ctcatgtaga
    23701 agttaaaatt acagcatcta catcatcttc taacaatttc ttagaaaact cttctccaaa
    23761 tctcttagaa ttgccaacac tcgttcctgt tcctgtagta gttataaaat aatctactaa
    23821 ttctccaatt acaccttctt tttcaagctc tctaactaca tctaatggta caactaaatt
    23881 tggattttca aggacatatg ctctgtcata ccccccatgt atagttgtaa attctttatt
    23941 tgacatagaa tccatatctg ttaaatcgta aattccatat ttagtagcac ttgaagattc
    24001 aattttgtct ggattatcaa ttggaactat ccctccagaa gttactaggg caagttttat
    24061 cttagataaa tctttaacag gtttcatagg tgtaactcta tcaaattcag gcattggata
    24121 ctcagtttca aagctttccc ctttcatctt tttaaccaac atatcaattg ctctttcaga
    24181 ccctctaagt tcatggaaga aattttttct tattcctctc attatatatc cttcctcttc
    24241 aggaggtcct atttcctcac ctctaaccaa tttaagacct agtttcgtca ttattggaac
    24301 tacctttcta agacttgctg ctgaatttcc tgtagacact atatgcaaat ctaatttaaa
    24361 catatctaca cctggatttt ctttatacat tcctgtaact acaggaatat ttaactcttc
    24421 ttcaactgcc ttacaaatag tcccacaagc tactccatat ctacctgcat taaatgctgg
    24481 gcctgcaata aataaatcgg ggctttcttc ttttatcatt tttaaaagtt cttgagttgc
    24541 actctcaata ttttcaccaa aatacgtatc tccacaaatt acagttgaga ttatctctgc
    24601 atcatcatta aattgactct gaaatgctat tccaggtcct actacaccag cccttttttc
    24661 tggcggaata tctgcttttt cctctccacc tataccagca aagaaattgt ttatataatg
    24721 aaccactctg attttactca tctcttaatc ctccaaatca ctttatagtt attacatcaa
    24781 ttagaccaac gattacatca acagaacttt atattcaaat acttatttaa taatatcttg
    24841 ctgtcaaatg attatagcca tttgctatag ttgatgctat tataatttgt agctctgcat
    24901 ccatgcttcc gtcttcattt aagcatcctt tatacccacc tatcatcatt tcaacataat
    24961 ctaaagttcc tataattttt tccattgctg ggaaatgaac cactagattt ccttgaccac
    25021 aagaaacaac tgcatctgct tccttagtag cgtctgctat agattgactc ttgccatctt
    25081 ttccaggaaa ttcatccgtt atcaaaacta catttgctcc aacttcacta cattttctac
    25141 aattcatcat taggtcagta tctggattcc cataaccttc ttctgtcact agaactccat
    25201 caactcctaa aaattctatt aatttagcta ccatatcaga gcttctctct ttatcgacta
    25261 agaatacgtt ctcattagtc aaaataactc ctataaagtt taaatctttt ccatgtcttt
    25321 tatataagtc atgtataact ggattattta aatgatggaa tgttgtaacc ttatcacatg
    25381 gtgctacaca gtttccagat attatagctc catccattat ttcagttgga tacataaatg
    25441 taggcactat ctgtttagca tccaccccat agtaataagt gtcatgtaaa agtccttgtg
    25501 attgtaacat gtgaacatat gctactgttg gcaggtctgg atattctttt acttgtttta
    25561 ataatggctt tgtctcatat acaatgactt catctggctc aacttctctt cctgcctcac
    25621 ctacatatgc acctattttt aatcctgcaa ttctagctgc ttcttcataa tcatgagtat
    25681 ctataccatc ctttgctttt ataacaatac atatattatt tgtttttgaa aaaggtgtat
    25741 atttagcagt aggaccactc atatcaatta cgccttcttg aaatccaact atatttccac
    25801 aagttacaac acaagctcct aaaagtacat gggttcttcc acttcctaca gtcttcactt
    25861 tatttataat tccaggaaat attttgcttt catctccaat tttaactcta ggctctatta
    25921 catctttaac tggagctatt cttattgatt cgccaggtct tgcaagttca acatttacac
    25981 ttacaatcct ttcatcttct aatactatct tttctatttc ttcgctacta atatatagta
    26041 ctccatcttt tacttctgtc ttttctccaa attcaacatt ttttataaat atattcccta
    26101 gctctagctt catatgaaaa tcccccttaa tatatttaat cgcaattaaa aatatttatt
    26161 acgtttatta atatataaag cattttctat gccaattatt taaaatatat attctatgta
    26221 ttaatgtcat agaaattttc atttttaatt tacaccagta ttgaatttac caataattat
    26281 tgtaaatatt aatttttaaa attataataa aaaaagataa acagattttt tctctttatc
    26341 ttttaataca gtttgagaaa tttttttctc acttaatgag aagttttttt ctcacttaat
    26401 attatactct gatattttat tggttaactg tcttctacta atctccaatt ttttagctgt
    26461 atttgaaata ttatttccac acaaagataa aactttttca atatactcac attcaaactc
    26521 ttttcttatt tctcttaaag gtctaatact tattttatca tctatgtata cattatttga
    26581 tattaaattt aaattgtctt ttgataaatt gccttcttca cttaaaacta caagtctatt
    26641 tattatattt tttaattctc ttatatttcc tggataattg taatttaata aaaaatcctt
    26701 tacttcctta tcaatcgagt gtatcttttt atcatgttca atttggtact tatttaagaa
    26761 aaattctata agagtagtta agtcttctct tctctttctt agtggtggta tagttattgt
    26821 tattgtactt attctataaa aaaaatcttc tcttatattt ccatttgata tttccacttt
    26881 tggttcttta ttcatagcac aaattaacct aaagtcaact ttaatagatt tattacttcc
    26941 tatcctctct atagatttgt cctcaagtgt cctcaaaagt tttacctgaa catttagagg
    27001 tatatctcct atttcatcca aaaatagagt tcctttattc gaaagttcaa atctaccttt
    27061 tctactatct actgctcctg taaaagaacc tttttcatga ccaaacaact cagactccaa
    27121 tagattttct gaaaaagaac aacaatttac aggtacaaat atctcattct ttcttggact
    27181 tatactatgt atatatctag ctaatatatc ttttcctaca ccagattccc ccaagattaa
    27241 tatattaaca tctttacaag cagctttttt tgctattttt atgatattat taaaatctct
    27301 atttttagat tccaaagtaa attcaaaatt atttttttgt acagaaacag atattttact
    27361 tgcctttacc ttttcaactt cttctaataa attttcaatg ggattacttt ttataaaata
    27421 agataaagct cctcttttca tagcatcaac tgcattttca atacttccat atcctgtaac
    27481 taatataacc tctatatctc tattaataga tttaattcta tctaatagct gtactccatc
    27541 catatttttc atcataacat cagataaaac caaatcataa tttttatctt ttttaattat
    27601 atttatagct tcttcaccac ttagtgctat atctacaaga tagcccttct tttgtagaat
    27661 ttttttcatt accactccat attctagctc atcatcaact aatagtattt tcattatata
    27721 gtcacctctt tatttaatgg aatttttata tgaaaacaag ttccaacccc caatttactt
    27781 tcaacactta tatctccatt attcttttta atctcattat aagtaatata taaacctaaa
    27841 ccagttccct caccaattgg ttttgttgta tagaagggat taaatatgtc ctttagggca
    27901 tcttctttta ttccttcacc attatcttta aaatctataa ataaacaatg atttttttca
    27961 taacagtata taataatttt tccatcttga tgtattgcat ctattgaatt agaaattaaa
    28021 tttataaata catgttttaa cgattctcca tttatatagc atactaaatt atgttcacag
    28081 tcaattttta tttcaacatt ctttaactgt aacattttat attgaagttt cactatattt
    28141 tcaataaaat ttcttatatt tatatgttct aaattatcat ctgatattct tgcgaaattt
    28201 aacaagttgg ttattatatt acttgcccta tctacattac tttctattga tttaacacaa
    28261 tcattcactt cttccattgt aacgttatct tttaatagat agcaattatt tcttattata
    28321 cccaaaggat ttcttatctc atgtgctacc ccagaagcta attgtcctat agatatcatt
    28381 ttgttttctc taagtaattt cgcctctact attttttcat tagttatatc tttaataaga
    28441 actactatat actcagtatt atttttttta tactctacag gaaaagtgtt tatctttaaa
    28501 attttattgt atatttctat ttcactagtt ttattagtat tttcagagaa ggtattttta
    28561 ataacacctt ttatcatgct aatcaaatct gctatcttat aactcatttc acccataaag
    28621 tcatatagta ctttgttcga ttctactata ttgttatttt catctacaag cattattata
    28681 tctgtaatac tattaaaagt tgcctctaaa gtttttttat tttctattac ctgttctgtt
    28741 ttccttttga tttctatctt taacaaatat gtatagctat aaaaaacata aattgatatt
    28801 aaaattatac ctataaaaag ataaatacta ggcacaattc ctcgctcata caatatatca
    28861 tcaacttcat tatacgtaga ataccatttt ttctttaaat ctttatacac tccatttttc
    28921 tgaagtttaa aaatgccttt atttaaaata ctaaccagct cttcatattg tttaggtaca
    28981 gcaagaactg cttttttagt atatatagga ttacttaaaa cactgtattt atttgaaagt
    29041 ccataattat ttatatagta tcgcaatact ggttcatcac caacaactgc gtctactttt
    29101 ccagacatta aatggttgac tccagtcttt atatctggag tcaataaaat gtttatatct
    29161 tgaatttttt gctttaaaaa atttatagaa taatcacctt ctggaattgc tactgttttc
    29221 ccctttaaat ccatgtaact atttatatct tgggactttt tatctttcaa tatatttgca
    29281 ctcaaagtgt atattgggtc agtaaatata aatttatttg ccctttcttt tgatggaatc
    29341 aagtcaaaaa actttatact atcatctatt gaatttacga aagattcttt ccaccaatta
    29401 tttggtttaa aataaaaatc tctaccaatt tgaattgaca gagaatttat taaatcaaca
    29461 ataattccct tatactgtcc atcttcctta cccttatatc tcaaaggagg tgaactttgg
    29521 tcagagctgt aaatcaaatt cttgtgtttt tctaaccact ttttttcttc ttctgtaaat
    29581 ggaagtgact tcttaatata ttcaaataca tttaaattat actccatatt tacatacata
    29641 tttgtaagtg aaaatactac taaaaatgaa taaataatcc ctataataac aatctttttt
    29701 ttattcactt taaaactcca atcttctttt ttactataat aaattcaata tttaataaca
    29761 aaatcctact tttttcatta aatatttata tttattataa aactaattga atagatgttg
    29821 aaattatagt cattactatt cctatcaatg cttcatatgg aattaactta aatctttcac
    29881 ctatatccat gtttatacta cctgaactag tatgaaatag tgagccatgt ggtaattgct
    29941 cgaatacact agacccagca tttactattg atgcacctga aatcggtgat agcccaccat
    30001 ttattatagc atcatgaaaa gtagatgatg ctatagtagc accagctgtt gatgatgctg
    30061 ttgctaatga cataagtata cccgaaactg gtgccaataa aaattgtggc atatttaaaa
    30121 attgtaaagc acctattgta ctctgttgta attcagacat ctgtataatt cctgcgatag
    30181 tccctgttcc aagtaataat atgcataccc cttgcatctt agataatcca aaagctaaat
    30241 attctcttga attgttcaag tttcctgtga caattagagt tacgattcct cctattggaa
    30301 gggctatcat tgggtctata actataggag atacatttcc taaaaacaat agaaatatag
    30361 ctataattgg accacataat gatttaaata aacttggtaa atcttctctt tgctctaaaa
    30421 tttcatatga ttgtacttta tttcctttat ttattaatat acttgctaaa ataactgtaa
    30481 taacaactcc aataattgct ggaattatat ttgccatcat aacactagag agattgacag
    30541 aaaaattatc tgctactgct atagtatttg gatttggtga tattatatta cctgctttac
    30601 cccctcccaa catagctaat agtattgaca atttagaata atttaatttt ctacctatat
    30661 ataatcctat aggtgctaca gttattatag atacatccaa atttacgcct actccagcaa
    30721 gtaccatagt tgaaatggca atcgaaaata aagccctctt ttcaccaaat atttttacaa
    30781 tctgttctga tattttatct actgctcctg tttttattaa acttccagct aatacacctg
    30841 atgccaaagc tctaagaatt gatggtgata tattcatagc tccatttgcc ataaaatcta
    30901 cagtttgtgt tatatttgct cctccaacta atcctccaat aaatgctcct aacattaaac
    30961 tatatacagc ttgaaatttt tttataatta aaataattgc tattaataaa ccaaatatag
    31021 ctccaaaagt cgttatttgc ataatgtccc ctcctatcat aaattaacta tcttttgctt
    31081 aattttattt aaatatattt taagtattct gtatccactt tgtcaattat attttaattt
    31141 atttaattat attgaacata gttttttcaa aacctaattc tatatgttat aataatttca
    31201 tactacataa tcattttact tgattatttt aagttaatat tttttaaatt aaaaagagag
    31261 gatatttata tgaatgattt aaatttaggg gaaaaaatag ctgaagttcg aaaaaaacaa
    31321 aacttaagta ttcgagattt agcaaaacta gctgatgtta caccatcatt attgagccaa
    31381 atagaacgag gtcttgctaa tccatctgta aattcattaa aatctatagc ctcttctcta
    31441 aacgttcctt tatttacatt ttttgtatct gaagtagata aaaaaaactt gatagtaaga
    31501 catgataata gaaaaaaagt tattttacct ggaagcaaag aagttatata tgagatttta
    31561 attccagact ctagtggtaa tttagaattt gcaattatgg atttagctcc aaatacttct
    31621 tcttgtattg ataggattac tcataatgga gatgaaattg catatgtttt ggagggagaa
    31681 gttaaacttt ttatggatga tgatgaattt actttgtcca aaggagatag tgtaaaagtt
    31741 cctttaggaa caaagcataa atggcaaaat gactcaaata gtgaaagtaa agtaattttt
    31801 gcagtcatct tgtaaaggag taaaaaccat gaagacatat aaatttatat tttttgatgc
    31861 agatgatact ttatttgatt ttaagaaaag tgaatcacat gcttttaaaa aacttctatc
    31921 tgagtttgat ttagaattta attttgagaa ttatatagag tcatatagaa atataagtga
    31981 taagctttgg ctcgaccttg aaaaaaatat tataactttg aatgaactta aattacttag
    32041 atttgaactt tttgcaaata aaatatcttt ggatgttgat tctgaaactc ttagcaaaat
    32101 gtacttaaat tttttaggtg aatgtacatt tttaattcca ggtgcaatcg atatattaca
    32161 atatcttaaa aaaaagtata ctattgttat aataacaaat ggaatttctg cagttcaaaa
    32221 gaaaagactt gaaaattcaa aaataaaagg atatattgat ggaatggttg tatctgaaga
    32281 gttgaaaata tcaaaaccaa atcctgaaat atttaaatac gctctcaaaa agtttaattg
    32341 tcatgataaa tcttctgcct taatgattgg gaatagctta acctctgatg tcttaggtgg
    32401 aataaattca ggaatagata cttgttggtt aaattccaat aacagtataa attatactaa
    32461 tcatatacca acttatgaaa taaatacact tattgaatta aagaaactac tatagtttgt
    32521 aagtctgttc aaattaaata gaatattact ttgcaataat ttttttagtt tatacataaa
    32581 atgaccaaaa aaattattgc aattcataca caaaacaaat cttagtcttg aaaactagtt
    32641 aaaagcattt tctaggacat ttgctacatc ttgattctaa attttcttca tctcccatta
    32701 aaataagcat tgcaacactt tttatggggg atagttgatg ataatcattg atttctattt
    32761 ctatactatt atatttattt tttacatagt tataaatatc cttttgtctc tctacttcaa
    32821 aatctttatc tcctggatat atttcatgcg atattttaag actatcatac tttcctttta
    32881 aatacatttt tattttctca ttaatataat ctaaacatac tatacctatt ttatccaatg
    32941 ctatccctgc catcatattg caattttcca tatagtcatt catcttaata tcaattttat
    33001 cccctattgt atatagtaca gcaaatgctt ttttacattc tttaggtgtt ttattaatat
    33061 caacttcact tatatatatc ttgatatcta aaatatcatt tatatttctt atttctcttt
    33121 caacgatttc actaattgta tctggagctt ttctatttcc ataccccaaa aactttagca
    33181 caatattctt atctataaaa atatcctcta aatttatatc ctttaaaaga tatttatttt
    33241 tattactatt ataattcatc aatatcaatc ctatctaatt ctttataatt aattcttcct
    33301 gcttttatag ctgcttgtaa attttctact ggagtggtat ttaagcagtt acagccaaaa
    33361 tcacataaaa agttatcata tcctctcatc ttctttaaca attttagtgt ctctcttcta
    33421 atcttatctg gcttagaacg tccaagaagt tttattgggt ctaaattacc aatcaacact
    33481 atatctctag gaatcattgg agcaatttct tcatagtcta aaatttggtc taaacttact
    33541 gcatctatat tacaacttag catattatct aataattctc tggtgtctcc acatatatgc
    33601 atacctttcc aacaatcaag ttcattgtag attttattta aattttttac tatatattca
    33661 tcaaatctat ctttacttag ggttactgac gttggctctg ctattgaaat atattttgct
    33721 cctgctttat ttgcagctac agcatatctt cttaccaatt cagttgtaaa ttccaacaat
    33781 tcttctacaa attttttatc agttattata catcttaaaa gttgagtagc tccagctaat
    33841 tgacctgcaa gtgtaaatgg accttgtatc gattcatata gtggtttttt aatacttttt
    33901 gatataactg ataagctctc tatattgagt ggcatacgtc cactcgtata agggtctgga
    33961 acatctaatt ttcttaattt atctctgtca gttatagtat gtgtcaatac acttggaaaa
    34021 tcataatctg gtcttaatgt ctctaaaccc agagtttcac aaaatgtaat cccatcacag
    34081 aatgagtata taaaatctga ttcaaaatac ttgtccatag tctttgctaa ttctaattgc
    34141 aaatctacac tatcatatac ttcatatgcc tttttattta ttaagaacaa tccatttgta
    34201 cccatatcag gcagaaaaaa acctctatct tcactattta tatactgaag taaagtcata
    34261 tctgaaaaca tttaaacttc acctcctata agtttgttta ttaatttaac tgcttttgga
    34321 gcatttgaac tgtatccatc tgctcctatt tcttctgcaa actccatact tacaggtcct
    34381 ccaccaatta ttacttttgg tcttttatct atctcaatca tattaagctc gtctataacc
    34441 gatttcatat tttccattgt agttgtcatc attgaagata agcctattat atctacattg
    34501 ttttttatag cttcttctat tatatcttca ctttttctat ttacacctaa gtcaataacc
    34561 ttatatccag tggcttctac cattactttt acaatatttt ttcctatctc atgagtatct
    34621 ccttctacta cagacatcag aattactccc tttgattttt tctttacttt tccagttccc
    34681 ttcaaaagat taataccttt atttaatgca tctgtgcata ctataacttc tgaaagatag
    34741 tattccttat tctcaaactt atctaaagct cctatcatac ctttgtttaa accatattca
    34801 taaatatctt ccacatcaat atttttatct atagcaattt ttactaaatt ctctatatta
    34861 tctacaccca tatttaatat acattctgct atatcatcaa gtatgtccat ataatactca
    34921 tcctttctaa ttacttacaa aattgctttt tcaatatcca ataatttctc ttatttaaca
    34981 aggactaact ctaggtatca atcaatttta tttaatatca tctaaaacta ttgataattt
    35041 aaatttgcag tccatggaaa atctacagga aatgcctttg tagcaaattc atatatattt
    35101 tttagatgtt taaattcatt atactgttcc tcattttttt caaaaaacag tttattaagc
    35161 ttatccaaat tttctattac aagttcttct tctttgtatt taataatata tttattttca
    35221 acttgtttaa attccatgta ttttagtaat tcaaaatcta catattgact aaaataactt
    35281 cttaaactat cacacaactt agtaaaattt attattttca tagttccttg ttgatagtcc
    35341 aaagattctg tcccattaca tttcaactgg tctttaagat ttttcacatg tactttataa
    35401 tttaaatatt ctaatccaaa tttatttgca acatatttca atatattttc aacatttaca
    35461 gagtttaacc ctatttcagc aacttctcct acagtagaat cttctttttt tattgttctt
    35521 attatcaaat atcctattat attattattt tcctttataa ataccttctt gtaaccaatt
    35581 ggtccccagg caatagttgc tgcatgcaat agtttttgaa actcatctct cgttcttata
    35641 aatctagtac tattttgatt atatagttca agcattttat ctaaatcatc atctttttca
    35701 aaattagttt catcaaattc aactatttca tatgctattt ttacatcttc aggttttatt
    35761 gtatatttat aaaaactctt taccaaacta caatttcttc tactgtatag acttcttgtt
    35821 cctgatataa ttacaatatc tacaccatca taaaacattt tttcttctac tttatccaat
    35881 atcttagatg aatagcctct cttttcataa tctggatgag tacatactcc acctatagct
    35941 gcaaccttca atctatttcc ttgaatagat acatcttgaa ttagatagtt tacatcagaa
    36001 accactttat catcttctga tattataatc atattttcta tattattttt acttagtaaa
    36061 agaggaaatt cttccatcat agttggctta tgatttcttg atattctaaa tacatagttt
    36121 attaattcta ttactttatc aaattcttct aattttgcac ttcttggtct taattccatt
    36181 catattcctc caaatattat ttaagatact taaaactcta ttatctataa taaaacattt
    36241 attactacag ttctaattat atcttttttc tttacaattt ttaattgttt tttttaacaa
    36301 atttttataa aatataaacc taatttatag ttaaacttat aaaataaccc gttatgtata
    36361 atatattaaa atattttcta tatatttata tgactaagtt ctataactaa attgaaataa
    36421 tcactttttc aagaatgtta taattttttt attgtattct ttttgctata gtctatgaat
    36481 aaatcaatag aaaatcttct aagttgcttt taaataatga ctttatggtt caattgtact
    36541 aaaatagtat atgtaggtta caaataatct aataaatatt aaagtttgga ggtaatagat
    36601 atggcagatt gtaattcatg tccatcaaag ggaaattgta atagtcaatc aaattgttct
    36661 attgaaaata accctaacaa taaatttgga aaaataattg gtgttatgag tgggaagggt
    36721 ggagttggaa aatcaactgt aactgcttta cttgctaata agctaaacaa aatgggatat
    36781 aaggttggta tattagattc agatataact ggaccaagta ttcctagact tatgggtgta
    36841 aaaaatgtaa aagcttattc tgatggctct tatatttacc ctgtagaaaa ctcaaataac
    36901 ataaaagtaa tgtctataaa ccttatgata gatgatgaga atgaacctgt tgtttggaga
    36961 ggacctttac ttggaggagt tgtaaagcaa ttttatactg atgtactttg ggaagaatta
    37021 gactatttat taatagatat gcctcctggt actggagatg ttgccttaac ggttatgcaa
    37081 tctattccta taagtggaat agttatggtt tcagtacctc aagatttggt atctatgatt
    37141 gtatcaaaag ctgttaatat ggctaaaaaa atgaacataa atgtccttgg agttattgaa
    37201 aatatgagtt atatccaatg tcctgattgt tctaaaaaaa tcaagttatt tgaaggagaa
    37261 tctactgaaa agtttttaga tgatttagac ttagagcttt taggagaact tcctatgact
    37321 aaagaaatta tagatattac tcataatgga gttacagaaa ttagtgatga tttagattca
    37381 atattgacta atgttgttga aaaaattaaa taaataaaaa ttttataatt ttatatttat
    37441 caaaaaaaga ggcttgtatt tattttataa tcatacaaat aaatataaac ctcttttatg
    37501 tttatctatg ttttaaatac acaaaatatt cttctacttc atctccattt tttactttta
    37561 ctaagtattc attataatga gcattatatg gctgtgtcat tttgcattct attacatttt
    37621 ctatgtcttc taattctaaa agttctacat cctttaaaaa ttttctttct atgagttcca
    37681 ttaatctttc cataatatat cctcacttcc cctataatta agataaacta tatatcctct
    37741 taatacagag tttatctgtt tattatatta tatccaatat attacagttt ctaacatcat
    37801 tcataaatta ttttaacaaa tagagattga ttttttaata aatatgcctt gataaaatga
    37861 aacatagacc aactcttagt tttatgtaaa gaaaacttaa agaaaactat agattatatt
    37921 cacaaaaact actcagaaga tataacagta agtaatatat gtaatgaatt acaacttaat
    37981 aaaagttatt tttttctttg tttaagaaaa aaagtggata tacttttact aattttttaa
    38041 ataaagttag agttgaaaaa aacaaaaagt atctattaaa aaaagacttg tctattttag
    38101 acgttactgt actaattgga ttcaatagtc aaaattacta tagtataatt tttaaaaagt
    38161 ttaataacct tacaccaatt gaatataaaa atatttataa ctaaaaaata tcattctaaa
    38221 aggatgctat ttttttacat attttttaca attatagtta attctttgtt aaattgattg
    38281 tacataaaat actaaaaatc taagttcaag tatttaaatt gctatatatc ataaattttc
    38341 taaaattaac aacaacttaa aaatttaaca ttctcttaac gtatacttaa caaaacatta
    38401 atatttctat tgacaaaatt tgttattcta tattatggaa acaataaatt ttagttaata
    38461 aagtttataa ttcagataaa aaaactatta atttcttaag ggaggaaata tcgtgaatat
    38521 agtaattagc cttatcggtg gacttggact ttttctttac ggaatgagtt taatgggaga
    38581 aggtttacaa aaatcagcag gagacaaatt aaaaaaaatt attgaactct taacaagtaa
    38641 tgttgttatg ggtgtactgg taggtacagt cgttacaggt attatacaaa gttcaagtgc
    38701 tactactgtt atggttgtag gatttgtaaa tgcaggtata atgaatctaa gtcaagctat
    38761 tggtgtaata atgggggcaa atataggtac tacagttact gctcaattag tttcatttaa
    38821 tcttgaagga attgcaccaa ttgctttagg tataggtatt ttattctatt tatttacatc
    38881 aaatcaaaaa acaaagcatt tatctgagat acttataggt tttggtatat tatttacagg
    38941 aatggagttt atgaaagatg cagtagctcc acttgctgaa tataaagcat tcactgatgc
    39001 acttttatat tttagtaaaa atcctgtatt aggtatattg gcaggatttg ccataactgg
    39061 tattgttcaa agttcaagtg catctatggg tatgttaata gcactagctt ctcaaggaat
    39121 acttcctcta tcatctgctt tacctattct ttatggagat aatataggta cttgtgttac
    39181 ttcactttta tcaagtgttg gtgcaagtag aaatgctcga cgtgcagctg taatgcattt
    39241 aagttttaat gtcattggta caataatatt tatgcttgtt ttaaataaac ctatatcagc
    39301 catagttact cattttgacc caactgatac agctagacaa atagcaaatg cacatacttt
    39361 atttaatctt acaaatgtta taatattatt accattttct aaatacatag ttaaattagc
    39421 aaatagactt atacctatta aagaaactga atcagaaata gtaaataata ctaagtactt
    39481 agatgaaagg atgtttagca ctccatctat agcacttggt aatactgtac aagaagttgt
    39541 aagaatgggt cataaagcta caaactcttt ggaacattca attgcaggat ttttaaataa
    39601 gagcaatgaa gatattaata aagcttttga gtcagaaaaa gttgtcaata agttacagaa
    39661 agatatattg aactatttgt taaaactttc taaagaacct cttagagacg atgaacgctt
    39721 tagaacagat ttgcttttta atactgtaaa tgacattgaa agagtctctg accatgcaga
    39781 aaatatagct gaattggcca tgagtgttaa ggaaatgaac attagttttt ctgatagtgc
    39841 gataagagaa atatacgaaa tatacaataa gacaattact aattttaagg atgccttaat
    39901 agttttagat gttaaagatt ttgagttagc aaataaagtt ttagaagttg aaaatgaagt
    39961 aaattattta gaaaaaactt ttagaaattc acatatgatt agactaaata atggaaattg
    40021 tacaattgat gctggtgtac tttatcttga cttacttact aatctagaaa gaatttctga
    40081 ccactcaaca aatatagtaa aacaagtatt aaaacttaaa caaaaaatat agtgattatt
    40141 tttatatata atcttaatca atgagaagta agaagctata gataatgctt atatcattta
    40201 tggcttctta ttttttatgt aatactcaaa tttttatagt attctcttat tattaaacag
    40261 cttctgccta gaatattcca tatatatatg acttctttca taaaacttga actgcccata
    40321 actaaagtca caagtataca taactatttt ttaatcaatt ataaccaata tttattttat
    40381 ttatcttcat tttaattctt cattcaataa tgtaataaga ttatttttta tttggatact
    40441 attatatcat ctaaatatgt tattatatat ttggatattt tcatattaat aggagggatt
    40501 ctacaatgat aaattatatg gtagaaatta tatatagcga aaaaataagc gaagtagaaa
    40561 acatgttgaa aattgaaaat atacaatatg aatttacttc tcgtgatggc tttatatttt
    40621 ttggttttta tgagatgaca gatgcatata gatttgagac tttatgttca gatgaaaaaa
    40681 ttcgatttaa aagaatataa taaataaaaa aagtacatat ttctaaacta tttgtttttc
    40741 aaatttaggt tgtgttttaa tgtagtgttg atatcataaa caattttaat aataaaaaag
    40801 taggaatatt atattaatat gctcctactt tttactcata tttattaata ttatttatca
    40861 aaactaccct acaaactgga atttatcatt ctttcataat tttaaactat catatttaaa
    40921 atatataaaa ttctacttga tttttgtata aacgtaatat caatcattat ccaatttaaa
    40981 agtatttttt agtaatttcc atttcatttt cttttaacat attaattaaa cttttatatg
    41041 taaatggtgt atttacatat tatttaatat ccaacaatta tataaagaaa tgtactcttt
    41101 gccttataaa gaattataaa gccaattcgt tttattatat tatttttctt tatacattaa
    41161 aaactttacc ttcaaatcct tatttatcta tatattataa aaatattctt aacctctttt
    41221 acgagatttt cttgacatat tatcagttag ataaaataat taaataatat attcagcaag
    41281 tatgtttttt actcttttaa gtaaatttcc acctgcaccc caatcaattt ttaaaactcc
    41341 aattgcactg cctgttgaag tagctttaat aactgttttt tctgtggtat tttcataaac
    41401 tacgattaat cctgcatcac tattatttct tgcgtaatac ttctcaaaag ttgtaattag
    41461 tataaattta tcatctccta aattataaga atcactaaaa actaaatctg catcaatatt
    41521 ttcttttatc attttttgtg cttctaaggg tgtaattttt acagtaaata tttctgttgc
    41581 cattttttat ctcctcataa gaatttattt tagacaaaac ataatctcta gtattttctg
    41641 atatatttat caaacaatat ccctattcct cctaacagag ctaatataga accaaaattt
    41701 ctatattgag aaatagattg gtctagataa atattatatt ggtcagtatc catgattcca
    41761 ccattttgtt gaataatatg ctctgcacta aattcaccca aacctataca gcagaataat
    41821 actactactc caattacaaa agcaaatata catattgtta atttaaaatc cttattttcc
    41881 atagttatcc ctctcataag ttaaatttat ttgattattt ttactagatt ttatattact
    41941 cttattatac aatagaacat atatttacat ctatttccaa aattgtaacc tttatagttt
    42001 tatatattta aattttttaa acaaaaaata cacatctata aattataaat gtgtattctg
    42061 caccattact aataatatat tatacttttt tacaaatttc taattattta taactattca
    42121 aaaataaaat tcatataaaa taattctatt gtacaattga aactttaata atatctccat
    42181 tttttctctc caagtgaact acttctccag ttaaatcata gtcaaatgct ttgactaata
    42241 tttcagtaac ctttttacca tctactacat catcttttcc attaaataaa tccaaagcat
    42301 tattctcaat cattcttttt gcaaaattta caggtaactt tatatgtatt ttatcgcctg
    42361 tatgtgataa gactcttatt cttaaaaact tttctaaatt gtttcttggt gtttgttttg
    42421 atgccatacg attaaatcac tctcctttat tttttattta ataataaatt ttattcttaa
    42481 aaatatcttt atatgtattt attatgaaag taacactatt attttctaat cttgttttat
    42541 attccttctt ctttaatata tttatttaat aaatatctat gatttataat aattgtatat
    42601 tttgagattt tactttacaa ttattgtatc taaatttaac aaaatatctt attagaatat
    42661 ttcaattaaa acaaaactgg tttattatat aaaaaataaa ttagtatact tattttttat
    42721 atatcaggag gatatactta tgaataaaat aatcaataac attttaaata cctgcaaaca
    42781 gtatacatat attttgccac ataaattgtt aagacagtat atagcacact atacaatatc
    42841 tattccagat acaagtatta aagaaaagct tacattaata cctgatgcta gtggatgtat
    42901 gatatttaaa tttgacaaaa aaggtataga aagcgcattc tggggagcca caacaaaaac
    42961 tactattgta aaaaatgata tagaaaatgt actttttaga gtattcgttg agtttcgccc
    43021 aggtggagta tattatttga caggtctttc tcaaagagaa tctacagatt taaaaatttc
    43081 acttgaagat tttaacacat tatttagctt agaggttaat tccatttttg aaagaacaag
    43141 tactataaag gaattagtag aacaattaga tatgttattc ttatcatact tattgaaatc
    43201 aaatatagta gatatgacta taccaattct tgaaaatgct agaaaacaga actctattat
    43261 gtctgttaaa aacatttcac aaattagttg ttatagtgaa cgacatttaa atagaatttt
    43321 taataattct cttgggatga gtgttaaatc ataccttaga ttacttcgta taaaccttgt
    43381 attacaagaa gtacaaaaca ataaaagacc atttgcaact ttagcacaag atattggtta
    43441 ttacgaccaa tctcatttta taaatgattt taaatctatt tgtggtgtta atccaacaac
    43501 ctatataaaa aatttgtccg atttttacaa tgaaaagtat aaattttgat atacaatcat
    43561 aataaaattt atatttaagg agtgacttaa aatgatagaa tcaagatgtg gaattttatg
    43621 ttatgaatgt ggatacaagg aaaaagtcaa ttgtaaaggt tgtacagata ttgagaaacc
    43681 attttggggt gaacaatgtc ctgtaaaatc ttgttgtgaa gataaaaacc ttatacattg
    43741 tggtctatgt gatacatttc catgtgaaat gcttaatcaa tttgcatatg acaaagaaca
    43801 aggtgatgat ggcaaaagaa tttctcagtg caaaaaatgg gctgtactag ccttataata
    43861 tactctcttg ttataaaata agtttttgta aggtaaattt tttaaactgt tgtagaaatt
    43921 tctgcaacag tttttataat taaatttaaa ggttatttaa ttaaattaat agaatagtaa
    43981 tttattgata aaatctgatt actaaaatta gaaatataaa atctcaatct ctgtctattt
    44041 aaaatatatg ttacaaaatt gaattaaaat agacttaaat tttattttat gttaaaatct
    44101 ttacagtaat aaataatttt attttaagga gataatttta tgaataatta cttaaaattt
    44161 gctacatatc aacttatagg ttttacatct tctataccta gccttattaa aattaaaaag
    44221 aatcctgata aatttagctt aaaggaaaaa tttgaattta tgcaaaaaca agctaaaaaa
    44281 tctttagata tagtgaacat agagcttaat ataattggta aggaaacact gccaaaagaa
    44341 ccacttctat ttgttgtaaa tcattctagt atgcttgaca gcttcatact aacagcaagt
    44401 gtagaaagac caattggatg tgtaattgca gatgaaccag tttggagaaa tatacctata
    44461 tttaaagaat gggcaaaatt actaagatgt gtatatgtaa acagaaaaaa caatcgtgag
    44521 ggtataaaga gtatagccca agcctctcaa aatatactta caggtcaaag tatggcagtg
    44581 tttccagaag gagatttaac atggattaaa gaaccaaatt cattggtttc ggagtttaga
    44641 agtggagctt taaagatagc atataaagca aaatgcccta ttgttccact cgtaataaaa
    44701 aattcaaaag atacttatga aggataccaa cctattggta aaattaactc tgttcctgtc
    44761 gaagtcgaat ttttagaacc aatttatgac catatagaaa atcctagact aaagtcttct
    44821 gtactaggtg aaaatataaa aaataagatg ataaatacaa tagaaaattt tagaaaatca
    44881 aataaaacat ttaaagaatt ttaatattaa aatttattga ctaaaaaaaa ttttaatgtt
    44941 agaatttttt ttaagaggtg attaaggtgg caaaaaatac aaagcaaaca acggttcata
    45001 ttgatgagac tctacttaag gaagttaaga gaataggaat taatgaaaat aaaagtatat
    45061 ctcagataat aaacgaatca ataatagatt atatattagt atacagagaa aacgaagata
    45121 aagaaaaaaa tgaacatgat aagaatctaa atgaaacaat aaatgaattt aaaaaagaag
    45181 aagaaaaaag aatgcaagca aaaagtgctg ctagagctat agcagaagca aaaaaacgag
    45241 ttctttacta agaaaaataa aaatcggtac aaattaagca ccgatttttt tatattaaaa
    45301 aaattacata tgaagaagtt ttgaaagaat tataaaagat gcaaattcca gtttgtacta
    45361 catagaaaaa tgtgaatgtt tagaggtgaa cttattatat gaaaagttat atcgcattat
    45421 taagaggtat caatataagt ggtaagaaca agataattat gtctgaatta aaagcaagct
    45481 ttgtagaact tggttattca gaagtttcta cataccttaa tagtggtaat gttgtctttt
    45541 taagtgatgt agatgacaac aaggttatct caaatacaat aagattaatg ataaaaaaac
    45601 agtttgaatt ggaaatacca gtttttatta tttcacaaga ggagttaaaa gatatactaa
    45661 ataatgctcc taattggtgg ggagataaca acaaagaaat atatgataat cttattttta
    45721 tgtttcctga cttatcttat gacgagtttt atgatgaggt tggaaatcct aaagaagagt
    45781 atgaaaaagt atatcattat aaaaatgcta tcttttggtc ttttagtcgt aaagattata
    45841 aaaagacaaa ttggtggtca aagactgcca gttcaaatgt aagtgataag attacaattc
    45901 gtacagcaaa tacggtaaga aaaatagttg gaatgcgata aaagataaca aacagccgat
    45961 aaacctcaaa aaataggtat atatcggctg ttcggaaact tataagaata tagtcaaaag
    46021 ttatgctgtt tttattgata aaataagttt aaaaatgagt ccagaaatat ttatataatt
    46081 ctggaaatac ttatatttat tctttaaatt aaatcaccaa caacttttac ttttataaga
    46141 agtgcattac caggaaggta tgcaagtgga acatcttcta tatttaatac ttctatagta
    46201 tcttctttag caccagcttt tagagcttta tttacagcct ctttttttgc atcttctatg
    46261 gcatcttctc tcgacatttt atctaaactg tatacttttt ctacatctcc acttatttgt
    46321 cctaaagctg caccaatagc atttgcagca gtataatgag gaggtcttat aacattgctt
    46381 atgcctttta gtttttcagg aacaattata cttcctccac cagttaaaac caattcaaca
    46441 tcatcttgac tagtcttcat ttggtctaca gcatcttcta attttaaaat aaccttctta
    46501 tatacctcat tacaatactc tttatctaag ttttcaacat tgctttttct atcttcaaac
    46561 gccatatcta attttgtaac aacatctgat aaagttagag tgtctccacc aaatattatt
    46621 gcatcttcag ttattctata tcccacactt tcaggaccta tctttatatt atctttttcg
    46681 ccttttacac atgtaccacc agcaagacca atagttaaaa catctggcat tctaaagttt
    46741 gtatgtactc ctccaattgt aactggaata gatgattctc tagggaatcc attatatagt
    46801 acacccaagt cgcttgtagt tccaccaaca tctaatacta ttgcattttt tacttttgat
    46861 aagaaggaag ctcctcttat agaatttgtt attccacatc caattgtaaa aattgggtat
    46921 ttcattgtat actctaaatt cattaatgtt ccatcatttt gactgaaata tatttgagca
    46981 tctataccta agtctttaag tgctttttca aatcctaaag atacagcttt acctacttga
    47041 gacaatgcag aatttaaaat agctccattt tctctttcta atatacctat attacctatt
    47101 tcatttgata aagatatagg aatatcccct aaaatttctc taacccattt tgcaacttct
    47161 tcttcttgtt gtttatttac tggagcaaat actccactta ttgcaacact ttccactttg
    47221 ccttttattc tattgcaaaa ctctacaact tcatctttac aaagttcatt tatctttcta
    47281 ccatcaaact catatccacc agataccaat attgaatcta attctatttt ttctcttaag
    47341 tcttctggcc aatctataaa tggaagaatg gcagtagtgg ccggctttcc tattcttatc
    47401 atagctacat tattaagtct ttttctttct acaatagcat ttgtacaatg agttgtacca
    47461 agcatagcat attttattaa tgaatggtca atcttacttt catctataac tttttttaag
    47521 gcattgtaaa caccagtttc aacatctttt gtagttgcca ccttaactga atgaattact
    47581 tttaattccc catccagtat acaagcatct gtatttgttc ctccaacgtc aattcctaca
    47641 cgatacatca aaatttcctc ctaaactttt attttccttg taattcttct actgttttat
    47701 attccacatc atatccaaag tatccaggtc caactgtctc aattcctttt tctgttctcc
    47761 acttttcatt acaaggaaaa gctactacca taacacgaga gccatatttt attctctctg
    47821 tagttattgg aaatccagtt tctaaatcta atactgctat taaatctggt gtaatacaaa
    47881 gtggtgtatc accttttttg gcaattaaat tctcattttg gaataatata gaatactctc
    47941 catcatactc attaatccca gcaaaaaagg catgtcctct agtaaatcca cctttcaact
    48001 ctctcttaat atcaattact tttccttcaa ataacttgta tccacacaat tcttttagta
    48061 tattctcaac agcacctttt gaatcagatt tattttcaag taaaaaccct cctatagttt
    48121 cagctattgt aagagtatta cctatagcag cttttttaac ttgagctcca cttaaattat
    48181 agtcactaat agaagaactt cctcccattt ctacagttaa agttctagct aatctttctg
    48241 accaaattcc atccacagga taaaggatgg cagaattacc tttttcatca gacattacgg
    48301 caggagatgc ctcatatcct tcaagataaa aagttaccat ttgagcttca gggaaagctc
    48361 tacccataga atctgcatct aagataggaa gtcctttttt agcagcaact gctataggca
    48421 taagtgagtt tatccctcct atttctatag gaattataac atccactttt ctatttaata
    48481 atttctccat tatttctaaa ggggtagtta actctacttc tgaaagtaat ttttctattg
    48541 taattacagg agaacccata ccagatactg gaactaccaa agcatcatca tcaagttcat
    48601 ctaaacttat tacttttaca ggaccatact ttttaatggc ttgttttgca accaatttac
    48661 ctacatatgg gtcacctcca cctccagttc caagcactgc tgcaccaact gctattttat
    48721 ctacactttc ttctgttaaa aatctcatgt tactttctcc tcatatttct aatttatttt
    48781 atactttata aacaaatttc tttatactgc tttgtctatt tcttgcttat tttttgttga
    48841 acaaagcact tttccaataa tagattgtac tacaaaccct gctataaaac catctaaagg
    48901 tgctatagta gtaagagtta taaatccata tgttgaaagg taagttatta atataccaat
    48961 tatccaagac actattgaac gtttaactat tggtttatat aatactcctt tatcaaagcc
    49021 tttaagttct tgctttacta tgtaatattc tgctgtatat acaccaccaa caggtgcaat
    49081 tacaattcca agtaaattta aaaatcctat aaaaccttca tatattccaa atacagccaa
    49141 taatgttgct ataataccaa ggactatagt taatactttc tcaggagcct tcttaagtac
    49201 aagagctata cttaatgatg ctgaatatac attacttgta tttgtagtcc attgtgctaa
    49261 tgtaagtact attatacctg gtatagcaat tcctaatgta ataaaaattc tcataatatc
    49321 tgaagttccc atacatttta ctaatactat cgaaactatt atcataaaag catttccaaa
    49381 ttgtattccc aaaaagcttg aaagagcaca gtctcttcta cttttagccc aacgacttat
    49441 atcaggagat acaattgcac caactattat tatactcatt gacagagaaa ctccacctgc
    49501 aaatgtcata gtagatttca tattatcatc aactgaaatt ccatttgctc taaaagctaa
    49561 gaatatagtt agcatcataa gaactaataa aaatggtact gaatacacac tcaacttctc
    49621 catggcctta tatccataaa ttgcagtact catcatcaag agaccaccta ttaggcttaa
    49681 aatctgcata ctgacatcta aattaaatat atcttttatt attatctgtg cattttgtgc
    49741 aaagaaacct acttgaactc caaaccaacc taatagagaa acccctataa ctagagaaaa
    49801 tatttttgct ccagcttctc caaatacata ctttgttatc atagatgtag ataaacttgt
    49861 agatgaacca accaaagagc atgtagtata caaaattgca gaaaaaaatg aaccaacaat
    49921 tactgacaat attgcttgtt tcattggcat actctgtgcc aactcagcgc ctaaaataac
    49981 agatgataaa tccacaccta ttgctactaa aactgaaaac atagctaccc aaccacgttt
    50041 ttgattctct ggaatctgtt ccagagcata gttaattttt tcttcttcca ttttcatccc
    50101 tccatttaaa tcgtaaaact actgacctta gcatatttta caattttcta atttataaat
    50161 ttattaacta tcatattttt ataattttca tttaatatat agttttaaat tttctgaaat
    50221 aagtttataa taaaaaacgc ctcttggaaa aatccaagag acgaatataa atccgtgtta
    50281 ccactcttat tagtaaaaat taattttact cactcatttt cttaaggcga attaaaccac
    50341 tattctaaca taattacaat agtattctcc aaagtccttt tcacataaat tccaatatta
    50401 gttctcagcc aaatctaact ctctgtaaaa ttcctttatg ctactttctt cttctacgaa
    50461 tatataatat tgatttgtag ttaatttatg atttatatca taatatatat gcaatatttt
    50521 gtcaacttaa aaagtcaatt acttacattt tttagtttta tatgtaaatt ttcatactat
    50581 tactatattt atataatgta tttttttaaa tttcatcaaa atatattttt tttatacttt
    50641 attatctata aatttacagt ataaataata tatatttaaa caattgattt tatataaaat
    50701 ataatttaat atatataaat aaaatattat attttaaaat tcaaaaacaa aaagctatga
    50761 ttttacattc atagctttat ataaccaata ttccaattta taactaaaat attttattta
    50821 aattaattct ctcttaaaat atatatttaa atcttaatag tatttactta taattatatt
    50881 ttaatagtga cttcattaga ttacatctat tgaatcattc acatttataa ttccttcttt
    50941 tagaaccttt acaaaaattc cttctcgtgg catcacacag tcacctgtca atttcttaat
    51001 ttcacatcca ttgtgacatt ttttccctat ttgagttact tcaacttcac attgccctat
    51061 tcttaacttt gtaccaacag gcagggaaaa aacttctatc ccttctgtag ttacattttc
    51121 agcaaaatct ccatatttta attggtcaaa gcctttcatt ttcattttat ctatgctttc
    51181 ttttccaagt aagcttatct gacgatgcca gtttcctgca tgtgcatctc caactatccc
    51241 atgatttatt tttagctctg cacatggtac aggaacttta attacaccct ttttctcact
    51301 tatatttatt gacactacct tcgccatatt tcctccaaat tttaacccaa tatattatta
    51361 atttactcga acttaaaatc tcctgatttt ccaccagtct tctccacaag atggatatta
    51421 cttataacca tttttttatc aactgcttta cacatatcat aaattgtaag tgctgctaaa
    51481 gaacatgcat ttaaagcttc catttctact ccagttttcc caagagattt acaggttgcg
    51541 tatatcttaa tagcagacat ataatcatct acatcaaatt ctaaatcaca tccaactaat
    51601 ttaatctgat ggcacattgg tatgtttgaa gatgtatttt tagctcccat tatacctgca
    51661 acttgagcta cagacaatac gtctcctttt tttatctgac cattttttac tttttctaat
    51721 gcttccttac taagagtaat tgtagctgta gctacggccg ttcttttagt atcatctttt
    51781 tcacttatgt ccaccatctt ggcataccct ttttcattta tatgtgttaa cattacttat
    51841 cctccaattt catacatacg cctatttgta tcactacatt tattttctat taaatgatgt
    51901 ttttctggtt tttgttttat tatatctttc atagattctc taaataacaa tggtttatgt
    51961 aaaaatggtt ttatatctat ttcttctttt gaatgtagac ataattttat tgcaccacta
    52021 gaagtaagtc taatacgatt acaagtgtta caaaatgaac agcttaatgg agttataatt
    52081 cctattcttc ctttagctcc tttaaacata taatattctg ctgtactttt ttcatcattt
    52141 ttgactttat ataaaccata tattttttca atcatttctt ttacattaaa ataacccttc
    52201 ttataaactc tattagcctc acctaatggc ataagctcta taaatcttac atcaattggt
    52261 gatttaactg ttaaaaacat aaaatcttta agctcatcat cattaaaccc acttatagca
    52321 acgcaattta actttacttt tatacctaag tttaaacaag attcaatcga ttttaagaca
    52381 tcttttaagt ttcctcctct tgttacggat ttatacttat attccttcaa agaatctaaa
    52441 cttatattaa ctttatttaa gccacatttt tcaagctcaa aaattctatc agaaagccca
    52501 atagcattag tagtcattcc tatgttattt attccacatt cttcttttgt aaattttata
    52561 agctcattta atttaggata taaaagaggt tctcctccag taaatctaat ttttgttata
    52621 ccttgttcag ccatagcctt tataataaac ttgtagtctt caaagcttag attttcattt
    52681 atataatttt tatcaaattt tacatctggt ggcatacaat agacacacct taaattacac
    52741 ttatctgtaa gtgaaatacg aaggtagtct atttttcttc catacttatc aatcatactt
    52801 tatctacctc tttgtctatt ttttatctat ctagattata tactattcac tttttttagt
    52861 ggcacattct gtagcttctc ctcttaaaac ttctatgcca tggtctaaaa catcaattat
    52921 aaaacttaga ttttcaactg cacctttagg acttccaggt aaatttatta ttatagaatt
    52981 atttcttatt ccactcacac ccctacttag tatggccttt ttagtaattt ctgtggattt
    53041 cattctcata tattcgctca gacctggtat ttctttttcc aacacttcct tagttgcttc
    53101 tggggttata tctctttttg aaaaaccagt acctccattt gtaagaatta aatctatttt
    53161 attactatta caaagtctta taatattttc ctttagcatt tccttatcat cttttataag
    53221 tacatactca gtaactttat aagctcctgt attttcaaca aattcagtta acttttttcc
    53281 tgttatatct tctctttttc cttcatatcc tttatcacta agtgttataa ttgcaacatt
    53341 aaacatatgt tctcacccct ctatacattg attaagtcct ataaataaaa atctctttta
    53401 ataaaaccta ttttctttta ttctcttttc tatcagcaat ataacatatt atatttattt
    53461 tttatttata tcacctataa tacatacatt ttttattatt ccaacgttct caaaatgaag
    53521 atattacttc aaaactgtat taaatataaa actaattata catgtcacat acataatgaa
    53581 tgtaagtact tttaatttct ataattatta taacattgtc catatttttc tctacaaata
    53641 aaatttttaa agtctatacc atacattata taatataatt ttacttattt atataatatc
    53701 accctaattt tattgtcata atagttaaaa tttcttctca aattagtttt ttcaaataaa
    53761 aaaaggcatc cataaaattt ttaaaagatg cctcttttta actatttata ttttattttt
    53821 caagaatact attatcatct tctaaaacaa ctgctgttcc ataagcaagc atttctgctg
    53881 ccccttgcat aactgaagct gaagacagtc taaatgctat tactgcgttt gcacctttag
    53941 cttctgcatc ttcaaccatt ctacctatgg caatttgtct tgcttcagtg agcatttcat
    54001 tatatccagt aagttctcct ccaacaagat tcttaaaact tgctcctata tcttttccaa
    54061 catgttttgc tcttattgta cttcctctca ctaatcctaa aacctttgat atctttttac
    54121 cttctacttt ttctgtagtt actattaaca taatatatca actccttagt atcctattta
    54181 atacattata tcatgtaact cacaattctt ttaacaaata ttgtaattta atgtttcatt
    54241 aaccaatctg tacttttatt aaccaatcta tactataaaa taatatgttt tattaactaa
    54301 ttatattttt attattaaga aatataattt tatctagtca actcatcata taaacttaaa
    54361 ttatattcta tatttaattt taaatcttta gtctttttaa tcatcatttc actaaagctt
    54421 cctttttcaa accacatatt ttgtatatcc aaaagctcta cttcttctaa aatcacatcc
    54481 atcttagatt gtttatcaat aatagctaca acatcaatat tgtgtggaac atcttttaaa
    54541 cattcataca catctattcc ttcaataggt tttttctctt catctatagc aacaactttg
    54601 tacatattcc ttttaagttc atctaatatt ttatatgctt tactttcttt atcgctatta
    54661 tttaatatta ctgcccaaga atcgcattta agtaaattca taaactctcc tccatataaa
    54721 tcctactcta ttttacaacc atagctaatt aaactttagt taatttttca tactcatcaa
    54781 cagtgtttac atttaaaaat aaatcttctt catcaaagta tatataactt ttatctattt
    54841 tatctataaa gcttctgagc tttaaatcat tttcccttat acataaagat actttattta
    54901 ttatactctt tttatatcca gaacacaatg gttgtaactt tccatttgtc actgaaatca
    54961 cacttttatc attcatttta ttagctattc tttcgactat ttgattattt agatatggca
    55021 tatcacatgc aattgtaact atatcatact ttgcatattc aagagcagta tatattcctc
    55081 caattggacc aacatctttt actatatcat tataaacttt aatatcgtat ttagaatata
    55141 attcttcatt attagatatt attatcaact catcaaagtt tttaaatgct tctattgcaa
    55201 tttcaataaa aagcttatca tgtaactcta aaaaggcttt atctctaccc attctagaat
    55261 tttttccccc tgccaaaatt acacctgttt tctctataca aatcgcctcc tccaaaataa
    55321 ttttacttaa ttcatatata tttgaaaaat ggcgcattag cgccacttca gcattgacct
    55381 attactcaaa gatttgaata atcttttctt taaatgtatt cataagcttt tctttttctt
    55441 ctaagtattc accataacac tcatattctc tacatataca atttatgatt tcacttgatg
    55501 taaagtttat tttttcaaga ttatagttat ataaaatttc aacactatca atctcactta
    55561 tactattaaa tatacaatca tatatatctt caattataag cttgctatct tcttcaaatt
    55621 ggcataataa ttgctcccta ttttcttcta gtagcacatt ttcttttata aactctacaa
    55681 agttttcaaa gtctttggta ttgttatatg gctctatttc aaataatatt ctaaaaaata
    55741 ggttccatgg aaattctgtg tttaatctac ttctaaaatg atttcctagg tctttacaaa
    55801 acttatcatc aaatgttggt tctctttcaa attctatttg ctcattaaaa tctatatcct
    55861 tgtttacaat ttcatttaat cttgcaaact catcaagcat aaaattacct aaaacttcat
    55921 cacttatatc ttgtttatta aaagaatagt tcaatatagt ttcacatggt tttttaaaat
    55981 ctacaacaaa acctatactt ttattcatct tttcagaaaa agcgtcatag actagtttcg
    56041 caaataattt ttcaatttct tttttactta ctttcatatt aaaagacttc cctgaatgaa
    56101 agtttttata aatacttaaa agctgattat ctatcatagt aagattattc tttatagagt
    56161 ccatcatatc ctttataaat ttatcagcaa gtaaatatgt attattttta taaattattt
    56221 tatgttctat ttcactccaa aacacattta caagagattt aatttgaagt tcaaatttta
    56281 cttctctatc taaatacgca aaaactccat ctattttata tatttcaaat ccattttttt
    56341 gcttattggg ttgcctctca gatagtttta atttaatatt cttattctct ttattataat
    56401 agtttatttt gtcatctgtt ttattaaaat atcttctcaa aagtctatat attttgtttt
    56461 catcctcaat aaatctacac tcaattctta ggcctattaa gtcagaaaca ttatgaataa
    56521 gattacttgc ttctccatat ttttttaaat atctatttct aattatcttt tctcttaaac
    56581 ttgattctga ttttattcta gaggttacat ttatatattc ttgattcttt tcatccaaga
    56641 tattttcaaa atactcttct atttcatctg atatagtttc taatgttggt gacattgtcc
    56701 tcaacatatc aatagactct tcaataaaat caaattcttt taatcccata aatttttaca
    56761 ctcctaatat ttaataactg ttaattattt cagtccttta tatttgatta cactattatt
    56821 ttaacatttt ttcctatcat aagtaagtat tctccaaaaa ccttcatata tatttcaaat
    56881 taacattaat ttatttagtt ttttactttt aattttaatt tttttaccaa ctttacatat
    56941 gaaatgagag ttattaaact aaatgagtaa ttttaaggaa tgagtaagaa aatatacatt
    57001 tattgtaaac ttttgtcatt tactatataa aaattatttt ttgcattgtt atatgaaata
    57061 taaaaaacga taaatcaatg cttaattaaa tgaaaatata acaattaaaa caatgtctaa
    57121 gtagatatta attcaaaata caagtaaata catttatttt taaatacaaa aaataaatta
    57181 ccactaatta aattagtggc aatttattga aaacatatta tcattttata ccattactaa
    57241 atatcttaaa taaaactaca cttaattaaa accctatata aatacctatt gttaaaaaga
    57301 ctagagatac agctgtcaaa atcaacaaga taggcattat aaatcttacc cattttgaaa
    57361 atggaatatg ggctactgca agtgctccca tcagtactcc tgaagttgga gttataaagt
    57421 ttgtaagacc cacaccaaat tgataagcgg ttactatcac ttgagccgat atattaacca
    57481 aatcaccaag aggagcaagt acaggtactg taagtgaagc aagacctgaa gatgatggaa
    57541 ttaaaaatgc caatgcagct tccaagaaaa atgataaata tacaaatata acctttggaa
    57601 gcccacctag aaaggctgct gcggaattta atatagtatc tattataaat ccattttgag
    57661 caattattac gattccacga gccaaagcta tagcaagagc tgcagatgct aaatcttttg
    57721 ctccatctat aaaactttct gagatttcaa tttgagataa tctaccaacc aatccagaaa
    57781 gcacacctat tgcagcaaaa cacattgata tttctggaat gtaccatcct tgacttaaaa
    57841 caccccaaat cattattgcc atccctattc caaatatagc aagaacagat acttctttaa
    57901 aagtaaattc ttttatttct gttgaagttt gattaagtat tgatttatta tttttatcta
    57961 tttcatatac tattgaactt tcaggatttt cctttacctt cttagcatag tacataacaa
    58021 atgctatact tattagtata tatgctataa aaataactac tctgtaagtt actcctgaac
    58081 caggagcaag ttgagctagt gcctgtgcaa taccaactga aaatggattt attgttgaag
    58141 cggcggctcc tgctgctgct cctataaata caattgctat tgctgttaga gaatcatatc
    58201 ccaaggatgt catgagtgga acaaatatca tataaaatgg taatgtctct tctgccatcc
    58261 caaatgttgt acctccaagt ccaaataaaa tcattgatat tggaattata agaagttctt
    58321 ttcccttaaa cttagagata accgaagcta ttcctgcttc tatagctcca gtcctattta
    58381 caataccaaa agcacctcca actattaaaa caaaacctac aacttcagct gaatctataa
    58441 agccttctat tggtgcttta aaaacatctg caaatccttg aggattactt tctacacttt
    58501 gataagtccc tggtacaact accattctac cttctacatc ttctctacta aattcaccac
    58561 ttggtactat ccaagtcaat attgccatca agactattag taaaaatatt attgtaaaag
    58621 tgtgtggtat aataaatcgt ttctttttac tgtcagtcat tataatgtcc tccatacttt
    58681 actaaatttt aaatctttct aggatattgt ttaatctctc tgactaaagt tttccctttt
    58741 tacaattttt tattagcaaa gatataaaat aaaaaagcta ccttttaaaa tttaaaagat
    58801 aactttttta tttttattta agttaaaaat tcaatatact atatttacta attcaacttt
    58861 tcattataat ttgatatggt ttttttaata tctttagacc tcattatagt tgacattata
    58921 gcaaaatcat cgcagtattt taatgtttct ttgacattag atggtaaaat tcccccaagt
    58981 gcaattattt taatatcagt aatcttttta gcttctttta aaagctcaat tccttttgga
    59041 tttaatcctt ctttacattt agtttcatat atatgtgata atgttatgta atctattttt
    59101 atattttgat ttcttattaa tttttctaaa taatctactt cctctacttt atgtaaagat
    59161 aatcctagta ttttattttc attaaaatta tacttatttt caattaaatt caagaataat
    59221 ttaaaaggaa gatggatacc ttgacaatcc actttttcaa aaaattcaat gttactattt
    59281 attataaaat taaccttgaa tttatttcta cactcttttt gatttatatt agttttcaaa
    59341 ctttcatctg atatttgctc ttgaaaatct atacaattga ttttagtttt tattttcata
    59401 tataattttc ttagctcttg atattccaaa tccttttctc ttattattat attttctaca
    59461 ccactcaata tagactcttt aataacttct aaatatcgtt cctcactaca taattttctg
    59521 tttgttatca gatacattta aaatctttcc caatctttaa acacatgctg ataaccaatt
    59581 gagtttagca ttttctccac atctttaaca gtactttcat catttatctt aaattgagca
    59641 gtatcatgtt catcttgaga atgacctcct acatcagtag atacacctgc gctcaattta
    59701 gttactccta aaggtattat atgacttctc atttctaaat tttctctagt ggatatattt
    59761 atagctgcat gagggtcaaa taatctcata cataccatag cttgaactaa atcagtatca
    59821 cttatatcta ccaattcctc aaaacaccct ttaaaaggtc tcattcttgg tgttgaatat
    59881 gaaagctcaa tatgaggata tttcgttttt aagtatttcc catgcaatat tgtaaaaaaa
    59941 gtttcttttc taaaatcatt tagacctaaa agtgcaccta ttgataaagt cctcatacct
    60001 gcttttgccc ctctttcagg agcatctagt ctaaattcat aatttgattt tgggcctttt
    60061 atatgtactc tcttatatat ttcctcgtca taagtttctt gatatactgt taatccttca
    60121 acacctttat ctacaatgta cttatattct tctacttcca ttggataaac ttctatacct
    60181 atagagggaa atttctctct taatatttct atagcctcac ctatatattc tacacttgag
    60241 tgaaaactac tttctccagt caaaacaagt agatgtttga aaccttcttt tgaaattgct
    60301 tctccctctt ctctaatttc atccatagtt aatttttttc tttttattcc actctttata
    60361 ttatagctac aataaacaca ttgattaaca caataatttg ctatatacat tggtgtatat
    60421 aaacatactg ttttaccaaa gtattgaaca cttaatttat gtgctttttg tgccatatct
    60481 tctaaatgtt ttactgcagt tttagaaagc aaatttaata tatcaaaatc ttcaagcttg
    60541 tcttttgata aacttcttaa aacatcatta tcagtaacat tatttaaata tccatcaaaa
    60601 tcaaaatccc tatatttttc tattacatca taaaaactca tcaccaatca ccactttcta
    60661 taaattgcct aaaaaacctg ttaaaggaga agatgcattt gcaaattctg acacatttcc
    60721 tgtttttgca atatatgctt ctcttccacc ttctacagct aatttaaatg ctctagccat
    60781 ttgtacaggg tctcctgctg aagctatagc agtgttgaca agtactgcat cagctcccat
    60841 ttccatagcc tccatagctt gagatggttt tccaatacct gcatctacta ttattggtat
    60901 atccaactca tctatcatta ttcttatcat ttctttcatt tgaagacctc tatttgaacc
    60961 aattggagct ccaagtggca taactgcggc tgcattagct tctataagtc ttcttccagc
    61021 ataaaggtct ggtgtcatat atggaagaac tataaacccc tcatcagcaa gtatctttgt
    61081 agcttttata gtttcttcat tatcaggaag taaatatcta gtatctgata ttacttctat
    61141 ttttataaaa tctccacatc ccatttttct agatattcta gctattctta cagcttcttc
    61201 tgcattagta gctcctgatg tatttggaag tattgtcatc tcttttggaa tatacgttaa
    61261 tatgttttct tgtttattgt ctaaatccac tcttctaagt gccattgtta ttatttcact
    61321 tccactttct tttattacct caggcaatat attatttgaa ccatatttac ctgttccaac
    61381 caataatctg ctattaaatt catgtccacc aagtaccaat ttatccatat tatttccctc
    61441 cacgttaaat ttttttaata ttcaatcttt tttatatcta attttaatat ttacatatct
    61501 ataagtattt gcgttgccaa atttgccata tgatttgcgc agatggcaac ccttggagcc
    61561 ataagccctt caccaaattt agcttcattc acaaaatccc cacatatata aaacctgtct
    61621 tttatcttct tagtagttat tatatttgaa tcatagtaac ctgccatacc agatgatgct
    61681 attaaatatt tatcttttaa atttattaat acataattac atacctgtgc tttacatgaa
    61741 gcatcatcaa aggcctcaat tattaaatct gaatccttaa tagtatccat attgttcttg
    61801 tttaaaaaaa tatctcgttt atttaatttt ataaatggat ttattttttt tatattttct
    61861 atcatggcat cagtttttag ttttcctata tcatctataa aatactgttg tctatttaaa
    61921 ttagatggtt ctacaacatc ataatctata agtaaaagtt ctcccactcc tattctagct
    61981 aaagagatag ctatattgga accaagtccc cccaatccca atatagcaac tttccctttt
    62041 tttaatttat tatgtatatt tggagtatgt ctagcaatca acaagctttc caattcatca
    62101 agtgatggct taactccttt ttgtataagt gttaatttat cattttcaca aaggggcata
    62161 tctgttttaa ttggatatcc atttaacacc aatacatcac atttattgtt atagctatct
    62221 ctaactttat aagcagttgt attttcctca acatctgtta ataattcatt tacaaatatt
    62281 tttattttaa ccacctccaa taaagctaat aagctctaca atgtcctcgt cttttaatac
    62341 atatgtattg tagttagatt cttcaattat ctctaaattc acttcaacta caactctatc
    62401 actttttaaa ttatatttat ttaataaatc tataacagtc aaatcttttt caaattcaat
    62461 ttccttccca ttaaccttca ctaaatcacc tcctcttttc agcttctttt tattccagtc
    62521 atactagcca aaaattatat tagattaagt tcctcattgt ttaatatttt cttaactgtt
    62581 ctcattgagc acatttttcc acacatagta caactatcct catgagtagg agttgattca
    62641 tctctgtatc tcttagcttt ttcagggtct attgcaagtc taaacatctc acaccagtct
    62701 aaatcagctc tagctttact catcttatta tcccattcac gagcaccttt aacattttta
    62761 gctatatctc ctgcatgagc agctatcttt gcagctatta taccctcttt catatcatct
    62821 aaattaggca atcttaaatg ttctgctgga gttacataac ataaaaaatc tactccttta
    62881 gcacatgcta aagctcctcc tattgcactt gttatatggt cataacctgg tgctatatct
    62941 gtaaccaatg gtccaagaac ataaaaaggt gctccatggc ataatctctt ttctaatact
    63001 acatttgctt ctatttcatc aatagccatg tgtccaggac cttctatcat tacttgtaca
    63061 tttctttccc atgctctttt agtaagttca cctaatacta caagttcttg aatttgaaca
    63121 ccatcagtag aatcttttat acaacctggt ctacaagcat ctcctaaact caatgtaaca
    63181 tcatattctt cacatatatc caatatttta tcaaaattag tataaatagg attttcctta
    63241 ttatttaatt ccatccatgc aaacaataaa gaacctccac gagatactat atgagtcaat
    63301 ctctcatgat tttttatttt ttggcaaaca cttcttgtaa gacctgcatg tatagtaata
    63361 aagtctactc catcaatagc atgttgtctt attacattta aaaactcttc ttctgttata
    63421 tcttttaatt ctttttccaa atatcctact gcatcataca taggtactga acctatcatt
    63481 gcaggtgaca tttcaacaac cttttctcta aattctctag ttttgccata attacttaaa
    63541 tccattatag cttcagcttt catgtctatt gctactctaa ctttttcaag ttctttttct
    63601 atatccttac aatctcttga aattcctaga tttacattta tttttgttct taaattttta
    63661 cctacacctt ctgcacttaa agatttatga tttttattag ctggtataac aacttgtcca
    63721 tttgctatta attctcttaa ttcatttaca tctacctgtt ctttttgaga aacgatttcc
    63781 atttctttag ttattatgcc ttttctagca gcatccattt gtgttgtata gttcatatta
    63841 caatcctcca agattaaagt tatagttttt gaaaataaaa aaagtgcttt tcctcgtttg
    63901 gaaagcactc ttataatcgt atatacactt agacaaattt ctcctaacat tgaataattt
    63961 gcctatttat ataataaaat tatattaaaa agcttccctt cgcaagcatt atcttgatca
    64021 ggttattagg gtttgtaagt tacggcttta tctctcagct agccaattct agcgccccta
    64081 gctctaattt ttcattattt ttacaaattc agtataacac agcaaaatta ttagttcaac
    64141 acaataatac aaattttatt tttattaagt taaaaattac tctgctataa tattattttt
    64201 taagttttca agataagagt caagcatcac agctcttata ttttcatact ttattgaatc
    64261 tggaagtttt ctttttatgt tatttaaatt atcatagcca actttttcgc aaacttctaa
    64321 aatcatcttc tttttatctt cattataaaa attttctagt cctaattcaa atgatatact
    64381 atgtccatcc tttacatagt catgcacata tccaataatg gttgacaatg aaacttctat
    64441 ttcttgactg atactttgta tatcttttcc ttgatttagc aaatctaatg ctatttcatt
    64501 attttttcta ctttctccat ctaatattaa cttccttttg ccctttttct cccaaataac
    64561 attaatatta ttttctttta catatttatt aacctctgcc aaaatattag ctccatattt
    64621 ttcaaatttt actccaccta tgccagaaat atcttttaat tgttcttcat caagtggata
    64681 tcttccactt atttctttca aagccttatt ggctaaaatc atatatgcag gtaatttttc
    64741 ctttgttgca tattcttctc taatgactaa cagtttttca tataaaactt tatctgtatt
    64801 aacctctaag aaatcactat taacgttctt taaatcgaca tttttttcat ctattttttt
    64861 atttatatta tttttttcga catattcttt aattactgct tcaaaatctc taccatattt
    64921 ttgatattta atttctccta ctccagagat atctagcatt tcttctttat taattggata
    64981 actactagac atggctctaa gtgtaccatc tccaaatacc atatatggag ctatcctttc
    65041 ttcacttgca attgaatgtc taagttctct taaagcatta tataactcat cctctacttc
    65101 caatgatttt gtcataacaa tttctttaaa ctctactttc acttcacctt ttaaaacttt
    65161 catagacatc tcatttaatc ttatagtagg aaaactacct ctatttccat tgcctagagt
    65221 ctcaactaaa tctaaaaaac catgagaaac caatgtattt acaaaattct ttaagtcttc
    65281 actagaataa tctctcataa tgttatatgt agacaaagta tttaatccaa gctgtaaaat
    65341 ctttttattc ttagaacctc taagtacatc tacaatagta gtaacaccat aacttctttt
    65401 cattctagct acacatgaaa tgactttttg tgcatctata gttttatcta ctatttcacc
    65461 ctctactaaa caattgctac aattattgca attgtctata taattttctc caaaataact
    65521 caatattgtc tttctatagc atgaattact gtaaactaag tcaatcatgt attgaagctt
    65581 cttatgctga aataattttc tttcaggatt ttcaactcca atatcaatta aatatttttg
    65641 tatatgtaca tctcctggag aaaataaaag tacacactca cttttttctc catccctacc
    65701 agctctacct atttcttgat agtagttttc tatactttga ggcatattgt aatgtataac
    65761 ccatcttata ttaggtttat caatacccat tccaaatgca tttgttgcta ccattatatc
    65821 cacattatca tttataaaat cttcttgatt tttacttctt tcatttttag ataaacctgc
    65881 atgatatttt gatacagata tatttctctt agataaacca ttatatatat tttcaacttc
    65941 ctttctagtt gcaacatata taattccaga ctcattttta tgattttgaa tataatctaa
    66001 aatatactta tttttactag atgattttac tatatttatt gataaattct ctctatcaaa
    66061 tccagttata taataatctg gattttctaa acacagtaaa tttattatat cagttcttac
    66121 ctcttctgaa gctgttgcag taaatgctgt aactataggt cttttaggca aattttttat
    66181 aaaatcagaa atccttctat aactcaacct aaaatcatgc ccccattgag atacacaatg
    66241 tgcttcatct atcgcaactt gacttacatt gttattattt attagctcaa taaactcttg
    66301 tgcatctaat ctctctggag caatatagag tattttataa ttattttttc taatattatt
    66361 taatatttca ttaaattctt tgctgcttaa tgaactattt ataaaagcag cactaattcc
    66421 catagtcttt aaggcatcta cttggtcttt cataagtgat ataagtggag aaattactat
    66481 tgtcattcca tctaaaatca aagctggaat ttgataacat attgatttcc cccctcctgt
    66541 tggcataata gctaacacat ctttttcgct taagatagaa tttattatag attcctgacc
    66601 ttttctaaaa cttgtatatc catagtattt tgatagtatt tctaaaagtt ttttattcat
    66661 atattactct cctaatttaa attaattaga cttctttcct gattatgttc aaatttttat
    66721 ttttatattc acaatcgtgg tatttcaaag tttatagaca ttctatatta tatattaaca
    66781 tatatttttt aaaaaaatag tttgcaaagt aaaataattt atgatacatt ctaaatataa
    66841 atttaatact taatcttcgg ggtagggtga aattcccaat cggcggtata gcccgcgagc
    66901 caaggtaaaa cttggttgat ttggttaaat tccaaagccg acagtaaagt ctggatggaa
    66961 gaagatattt aatgagtgtt tttgtagagc aattttcttc tacttttatt aaacatttat
    67021 tgtagattat tctaaaccct gagttaattc tcagggtttt ttgtttaaaa attatccaat
    67081 taaacaggag gtgtacatat tgtgaatcaa aaagaaaaag atatttatta tatgaaaaaa
    67141 gctattgaat tggctaaaaa tggagaaggc tttgtaaatc caaatccatt agttgggtgt
    67201 gtaattgtta aagatagtaa tataataggc aaaggatatc atgagaaatt tggctctaat
    67261 catgctgaag taaatgctat aaacagtgct aaacaaagtc taaaagactc tactctttat
    67321 gtaaacttag aaccatgttc tcattatggg aaaacgcctc cttgtgtaga taaaattata
    67381 caaaataaga ttaagagagt tgtaatatct acattagacc caaatccact tgtttgtggt
    67441 aatggagtaa aaaaattaaa agataacaat attgatgtta ctgtgggaat attagaagat
    67501 gaagcaagag atttaaatga ggcatttttt tatcatataa aaaacaaaag acctctttgt
    67561 attgtaaaat cagcagtaag tctagatggt aaaattgcta caaaatcact agaatcaaaa
    67621 tggatatcta atgaatcatc aaggtatcta actcataaat acagaaataa ataccaaagt
    67681 ataatggttg gcataaatac agttttgaac gataatcctt tactaacttg caggctcaat
    67741 caagaaaaag tgtctcatcc tacaagaata gtaatagata cacacctaaa gttgccactt
    67801 aatagtaatt tggttaaaga taaaaccagt aaaactatag ttttcacatg ttgcaaagaa
    67861 agtataaaat tatctatgtt aaaagaaaat aatgttgaaa caataatttc tccttcaaaa
    67921 aacaacttag tagatttgga atttgtaatg tataaattag gagagttaaa cattgattct
    67981 gttctagttg aaggtggtgc tactctcaat gacagtctct ttagaaataa gttagttgat
    68041 aaagtcaaat tatttctatc acccaagatt ataggtggta aagatgcacc tacattcgtt
    68101 tctggagaag gaataaatca tttgtcagat tcaacacagt taacaatcaa taatgtaact
    68161 ttgatagatg gcgatattct tatagaatca gatgttttaa attaaatttt tgttaataca
    68221 ttcatatagg aggttaggat gtttactggc atagtagaag aagttggaat acttagaaaa
    68281 attactgcta atggtaagag tggaaaagta accatactat caaataaaat attagatggc
    68341 acaaatcttg gagatagtat agccgtaaat ggagtttgtc taactgtttc aaacctcgga
    68401 aaaaatgaat ttacagccga tgttatgatg gagacaattc gttccacaaa tttaggttta
    68461 ttaaatgcaa atgataaggt aaatcttgaa agagctatga gtctttcttc aagatttggt
    68521 ggtcatatag taacaggtca tgttgatggt aaaggaacta tctgcaaatt tgaaaaagat
    68581 gaaaatgcag ttttagtaag tatacgacct gataaaaaac ttttatcttc aatgatactc
    68641 aaaggttctg ttgctattga tggtgtaagt ttaactatat catatttaga tgatgaaata
    68701 tttaaggttt ctattatacc tcatactaaa attaacacta ttctcttgac aaagaatgtt
    68761 ggagattttg ttaatttaga aagcgatgta attggaaagt atgttaataa ttttatggct
    68821 aataactaca aggaattaaa ttctaatagt agtaaccata aatcaaatat agataaagat
    68881 tttttattta aaaatggttt ttaaaaataa taaaggagtg aattacatgt ttaatactat
    68941 tgaagaagct attgaagata taaaaaatgg gaaaatggta atcgtagttg atgatgaaag
    69001 tagagagaat gaaggagatt tattgatggc agctgaaatg gctactcctg aatcaataaa
    69061 ttttatggct acatatggta gaggtctaat ttgtctacct gccactgaaa aaaaatttaa
    69121 aagtcttaat atacctctta tggttagaga aaatacagat acatttcaaa cagcctttac
    69181 tgttactata gatggagcag atactctaac tggtatatct gcatatgaaa gagctgaaac
    69241 tgtaaaattg ttctgtgatg aaaattctac aagtaaagat ttcaaaacgc ctggtcacat
    69301 atttccttta atagcaaaaa ctggtggagt tcttgtcagg gatggacata cagaagcctc
    69361 agtagacctt gctagacttg caggttttaa agagattggt cttatctgtg aaataatgaa
    69421 agatgatggt acaatggcaa gagttgatga tttaatgatt ttcaaagaaa agcataattt
    69481 aaaaatcatc actataaaag accttataga ataccgcaaa ataaatgaaa ctactataga
    69541 aaaagtatct agtgctttcc ttccaacaaa atatggaaat tttgaaatca taggatatag
    69601 agatacttat tcaaatgaag aacacattgc ccttacttat ggaaatataa atatagaaaa
    69661 tactctagtt agacttcatt ctgaatgttt aacaggagat gtgttccact ctctaaaatg
    69721 tgattgtgga ttacagctag aatcttctat gaagaaaatt gtggaaaatg gaagtggagt
    69781 tttaatttat atgaagcaag aaggtagagg tattggcctt ttaaataaaa ttaaggctta
    69841 taaacttcaa gaagaaggtt acgatactgt tgaagcaaat ttaatgcttg gatttgaaga
    69901 agatatgaga gatttctata tggctgctca aatattaaaa aatttaaaca taaaaagtat
    69961 aaatctttta agtaataacc cggataaaat aaatcaatta gagaaatatg gaataaaaat
    70021 cgaaaataga atccctatta atgaagaaat taatgacttt aataagctat atttaaaaac
    70081 taaaaaagat aaaatgggac atcttttaga tattatataa atgattatat gatgatattt
    70141 ttctactaag tagtttttta taattaaaat taaagatatt tataaatata aatctataac
    70201 ataaataaaa ttggaggaaa taaaaatgat atatgaagga aaacttattg gaaaagattt
    70261 aaaaataggt ataataaatt ctcgttttaa tgaatttata acatcaaaac ttttatcagg
    70321 agctgaagac tgtcttttaa gacatgacgt ttctccagaa aatatagaaa tagtttgggt
    70381 acctggagct tttgagattc ctcttgttgc tcaaaaaatg gctaaaagtg gtaggtatga
    70441 tgctataatc tgtttaggct gtgttataag aggggctact tctcattatg attatgtatg
    70501 tagtgaagtc tctaaaggga tagcaaaagt atctttagac agtgaattac ctgttatatt
    70561 tggaatcgta actacagaaa atattgaaca agctattgaa agagcaggta caaaagctgg
    70621 aaataaaggt tatgattgtg ctatgaatgc gctagaaatg gcaaatttat ttaagtcttt
    70681 aaattaaata ccaacattca taataattaa aaaaccaata tcattcactt tacgataaat
    70741 aagctatttt taataataaa aacttttaat aaagctaaat tatataataa aaaaatatta
    70801 ctggaattaa aaattccagt aatataaatt aattcaatat tatattcata taaagcatat
    70861 acatactcta gtctttcaaa atggttttat aattttatac tattttttat cctaaatgtt
    70921 cctcagataa ttccctatgc cactctgata ccttttctag gccttctatt tcatctgcaa
    70981 taaacacagg gtcttttatt cctgattttt tttgacttgt ataatctttt aaagcaataa
    71041 atgcatattt tcctaaaagt gctattgcta ttaagtttat tatcgccatc aatgccataa
    71101 ataagtctgc aagattccaa actacatcta cttgagtaag tgaaccaaat aaaaccatgc
    71161 ctacaacaaa aactctaaat acattaagtt tagtcttact tccactcata aactccatat
    71221 ttgattcacc ataatagtaa ttaccaacta tagaactaaa tgcaaacaag aatatacaaa
    71281 ctgctataaa tatatttcca actggtccta tatgatgagt taaagcttct tgagctaatt
    71341 caattccagt tgctccacta ctactataac ctgaatataa taataccatg aatgctgtac
    71401 aactacatat tattatagta tctgtaaaaa cacctaaaga ttgaattaaa ccttgtttta
    71461 caggatgagt tacatgtgct gttgcagcag cattaggagc actacccata cctgcttcat
    71521 tagaaaatag acctctcttc actccagtca ttacaactcc cataaatgta ccaatcgcca
    71581 ttcctttaaa atcaaatgca ctttcaacta tcaatgctat aacacttggt atctctgtta
    71641 tattcattac aactatagcc aaagcaacta atatatataa tcctgcaaat acaggaacta
    71701 ttatttcaga aacttttgca actctatgca ctccaccaaa aataactatt gcagttaaaa
    71761 ttccaagacc tattcccata gccattttac ttattccaaa tgcattatta aatgcaagtg
    71821 aaacagtatt tgcttgaact gcattaaata caaaaccata acatatagtt ataagtattg
    71881 agaataaaat acccatccat tttttattta gaccttgttc catataatac gctggtccac
    71941 ctctaaaagc ttgaccatct ttcactttgt aaatctgagc taatgtactc tcaacaaagc
    72001 ttgatgcaga accaattaat gctataagcc acatccaaaa tacagcacca ggtccccctg
    72061 ctaccactgc aattgctatt ccagctatat ttccagttcc aactcttgaa gatgtactta
    72121 tacaaaatgc ttgaaatgaa gagatttttc cttccttttt tgcattttta ttcgctgtac
    72181 catcacccag aagtctaaac atttctataa aatatctgaa ttgtacaaaa tttgttttaa
    72241 tagtaaagta aataccaatt acaactaaca ttataattaa gatatacgac cataagtaat
    72301 tgtttacaaa tactactgca ttgttaatac tcgttaaaat accatttaaa aaattcatta
    72361 tattaattac ccccctattt agttttgttt tctcaataaa tcttaaaatc aaaaaaatga
    72421 ataattcctt gttaaaaatt cattaattta attataatat ttataaaatc aaattacaag
    72481 gtttaaaatg aataattttt ttaatatatt gcagttttat attcaaatca aacctttttt
    72541 tattattttt ataatataga tatatttaat attttataat tgttattgga tacaataaat
    72601 tctagtttaa agggtatatt ttttcgtttg tcgtttaata ttattatcaa tggaataatt
    72661 ttaaaattta tttaaataac aaaaattttc tttaaattct gtcaatttct caaaaacttt
    72721 gttaaataat atactttcat acatccattg aaaaaacaat aaaaaagtaa tactatatat
    72781 agtactagca ttaggcacaa aataatacaa atggaggtac ttatattatg gaatttcaac
    72841 aaataatagc tatatgtata tttttaatag ttatggcagc tattattaca gaaaaggtaa
    72901 acagatccgt agcagctgtt ggtggtgcac tattaatgat aatattcaat atacttacac
    72961 ttgatgaagg attaagccat atagatttca atactattgg tgtattagtt ggtatgatgc
    73021 tatttgtagc tgttgtcaaa aactcagggt tatttgaata tatagctatc tggactgcaa
    73081 agaaagctaa aggtgaccca tggaagataa tgatttgttt tgctattata acagctattt
    73141 tatcagctgt attagataat gttacaaccg tcttacttat tggaccaatg actatagtta
    73201 ttacacaaat attaggactt aatccagttc catttttaat aacacagatt ttagcttcaa
    73261 atataggagg aacagctact cttataggag accctccaaa tattatgatt ggtagtgctg
    73321 ccaatcttag ttttatggat tttgtaataa atttaggtcc tgctgttata gtaatacttg
    73381 ctataactat aatatgcttt agatttattt atggaaaaga acttgttgtg aatgaaagag
    73441 ctaaaaatgc aatattaaaa ctagatgaaa aaaaatctgt taaagataaa cctctactta
    73501 taaaaagcct tatattaata gcattcatac tttttggttt tatgtttcac agtacaatcc
    73561 acatagattc ttctgttgta gcactgacag gagcatctat aatgctttta ataggaaaac
    73621 aagatgtaga tgaaattatg gcaggtattg aatggtccac aattttattc tttatgggat
    73681 tatttgtagt agttggtgga ctagtagaag ttgggataat aaacaaattg gctcaagcat
    73741 tgattggact tacagaagga catcttgtat ttacaatgtt gttgatatta tggttatcag
    73801 ctatagtctc ttctttctta gataatattc catttgttgc aacactaatt cctcttattt
    73861 tgactatgca agctgaaggt attgatgtaa tgccactatg gtgggcaaca tctcttggag
    73921 cttgtcttgg aggaaatgga acactaatag gagcatctgc taatgttgta ctagcaggta
    73981 taggtaataa acacgttcat cctatctctt ttaaggagta tttcaaaata ggttttccac
    74041 ttatgattat atctattatt atatctactg tttatttaat tataaaattt taaaaaatat
    74101 agtataataa tactaaaggg gatgtgtata tatgaatatt aatactgttc aaggtgattc
    74161 gattgaagtt cttttaagac agcttggtgc cacaagaata tcaaaagtaa gtagtacatt
    74221 atattttatc aagtttgatt taggagacgg ttgggaaata tcttatactt ataatattaa
    74281 tgctaaagac caatattttt tacagagaat tgaaccatat cctattggta gaggtctatt
    74341 taatgatgaa tatgaaatag tatcatttat atcaaaggat ttaaaaaaat ttctaaatgc
    74401 taaaaatagt agtaacttta agacatttgt tgaagttact agaaaagtca attctatcat
    74461 tgataatgta gaggaactat ttttaaacta caatgtagat ggtgatgatt taaaaacact
    74521 taataaagaa ctcaatgaca tattaaatga tattgactat atagaaaaac atacaaaaaa
    74581 aatctaaaag tagtaaactt gtaaacttga aatattatta aggatactac aaaaaacata
    74641 aaaatctaaa ttttggtttt aaaagaataa aatcgtattt attaaaagaa aaaatagctg
    74701 atgaagtata tatttcatca gctgtttttt ttaatgatgt ccacatccgt catgtgagca
    74761 agtatggtct gatggaaact ctactaattt tccattttta agtaagtcta aattagcact
    74821 tatagtatca ccttctgctc tgtaaacttt tattcccatt ccatttaatt taattatagc
    74881 tccttgtcct attcctccaa caactactgc atctacagct gtccctgaca atgcttttaa
    74941 tggttgacat tttccatgtt catgatctaa atctccatta tctaaagatt taacttctcc
    75001 actttctaaa tcacacacaa caaaaattgg agcagaacca aaatgtccat atggtttact
    75061 atccaatcct ttattctcct ctactggtat acatactttc attattattt ctcccttctc
    75121 ttacaacatt tttttataga tttacattct ttactgcatc ctagatgtat tgtatttaca
    75181 tcaaatacat ctataaagct ttcactagaa ttacttaaca tagaatttat aaaatctaca
    75241 catatattaa atgattcttt attaatatga tataaaacat agtatccttc tttatatcct
    75301 gttattatcc caacatcttt taatattttt atatgttgtg aaacagcaga atctgaaatc
    75361 cctagatatt tagaaatccc cttttgacat atatttctct tggatactaa tataagtatg
    75421 ttaagtctag tttcatcact caatgcttta aatattttaa ccaagttttc cataagtacc
    75481 tcgttttgat taagtaatta cttaattaaa ttatagtact cttaattaga tttttcaacc
    75541 attattttta aattttggag tatattataa ataattccaa tttctactaa tataactttg
    75601 aattttatta ataaaagtaa ttacatatag attttaaaat acttttatta ataacttaaa
    75661 aataaaaaac tgtcttgaaa taataaaatt atttcaagac agttttttat aaatatcttt
    75721 aaaaagttaa tcaatataaa tattaagccc tctttaattt atctaaatag taaacagcat
    75781 ttaaagctgc tatttgccct tgaccagctg cttttatata agaatagggt tttccaacac
    75841 aatctccagc agcaaagcat ccatctatac tagtcttcat attattgtca actttaatat
    75901 gaatgccatc aatctctatt ccaggaacca atgcacttgg agccgtacta tcttttataa
    75961 cgaatactcc atcaacttca atgtggtttt ctttaaaaga tactttgttt acaagtttat
    76021 ctccatctat ctgtactggt ctgtcatgta taacttcaat agaatcatct aggttatctg
    76081 aacttctcat aagattatct tttttgtaca taggtataaa ataagtcttt gaagtgagtt
    76141 cacttaaaaa atttgcttct tctttagatt cttcattata tcctataact gctacctttt
    76201 tatttctata aagtggtgca tcacatgtag cacagtagcc tacacctctt cctagaaatt
    76261 cttcttcacc cttgattggt ctagtatact ctaccccagt tgcaaggatt acagtagtag
    76321 cttcatacat atcatttcca gacattattg taaagtattc tcccatagca taaatattat
    76381 ttattctttt attttcaatt gaaatatcca tactatctat atgtgattta aacttgtctt
    76441 ttaattcatc accacttata tcataaaaac ctaaataatt atctattgaa ggagctttaa
    76501 caagcttatt acttaaatta tcattaccaa acatgataat tgttttattt cttatttttg
    76561 catttatagc agcagacaat ccagctggac cactgccgat tatagctata tcatatctca
    76621 taatactcac ccatttttta taaatatgat tttacttgca tttcaatttt gttctttggc
    76681 atgaatccaa ttaaagtttc tactggtttt ccatctttaa atataatcat agttggtact
    76741 gtagatacat tgaattgttg agctatttct aagctctcat ctatatcaac ttttacaaat
    76801 ctagctttat ccttcatctc ttcacctaat tctgcaaata caggtcccaa catgttacaa
    76861 ggtccacacc aagttgcaaa gaaatcaact acaactactc ccttactacc ttcaacacta
    76921 cttctaaatt cagatgtatt tataactttt gccattttta aatcctccta ttaaacttta
    76981 ttatccctat ataattatac tatgaaattt ataaatataa atttactttt ataaggtctt
    77041 tttatatttt atactaatta gtatacccat tcttcatttc taaaaacaat tttttatatt
    77101 tttattattt taactttttt ggtattgaca attcaaatgt agttccaata tctacatcag
    77161 aagttacatt tatatcaata gataagttta aactaatcat gcgagctatt gaaagtccta
    77221 ttccagaacc ttctaaatct ttatttctta cattttcact tctaaaaaat ctatcaaata
    77281 taagaggtat ctcttctttt tttatgccta taccagtgtc acttataagt aaagttacct
    77341 catcctctat atcttctttt aattctaatg ctatctcatc acccaatttt gtatatttaa
    77401 aggcattatc aatgaaaatt aatataagct gtcttaattt atttttatct gttattataa
    77461 ctttattctt cagtttagaa ttaaacacga atcttttttc ctgaaactca gcaatgtcaa
    77521 tatagtcttc tgatatttct tccaataatt tttctaagtc tatttcttct aaattaactt
    77581 taacaataga gtcctcttta gtaagagaca ataaatcagt tatcattttt ttaagtcttc
    77641 tagtttcctt cattgcagta gctattgttt caacttcatc atttactgta ctttctgggg
    77701 attttaacat actttctaat tttgatgaaa ctattgttat tggtgttctt aattcatgag
    77761 aagcatcttg tataaactta gcttgatttt tccatgctgt ttctattgga attaaagctt
    77821 ttctagtgag atatacagcc acaaagtaag taattattac agaaattaat attccaatta
    77881 taagaacaga tgtaagctgt cttaaagaat tcatctcaga atctatattt ctaattatct
    77941 gtatttggta tctacctaca tctacattta attctctaaa agtatatcca ttttctgtgt
    78001 atttaaaaaa cgaatttttt ttatctagtc ttctatctgg aagtaactca tcaaaatatt
    78061 cattttgagt atagtaactt atccttccat cttcatatac atacaccata tctttaggat
    78121 ctttcagtct tattgggttc aaaaatgaag ttcttttaaa ttgagagact atatattcaa
    78181 gttcatcatt tatctcacta tcaattccac tatatgtaag tcccctaaaa tatgagtata
    78241 taaatataga aaagattatt aaaaaactac ctactacaat aatatacatt tttattaaat
    78301 gatttttagt actggtaaat acattcttat ttatcatcga atatatatcc taccttacgt
    78361 ttagttttaa tatatttatc atatccatat ttacttagct tttttcttag attacttaca
    78421 tatacttcca ctatttcaat agttgcatct gaatcaattc cccatattct atcataaatc
    78481 tgctctttta ataaaattga acctttattt aatacaaaat actcaagcaa gttaaactgt
    78541 ttgttttgaa gttttatttc ttctttttca atatacactc ttttttctag tgtatctaaa
    78601 tataaagatt taaattctaa tccgtttctt tcttttatct ttccattagt ccttaatata
    78661 gcgtataccc tagctactaa ctcttccata taaaaaggtt ttgtcaaata atcattagct
    78721 cctatagtaa atgcttctac tttgtcatct aatgtttctt ttgctgtcaa tataagtaca
    78781 ggtgtatcta tattattaac tctcattttc tttaggatat caaatccatt tatattagga
    78841 agcattaagt ctaaaataac taaatcatat atattttgat ttactaagta taaagcttct
    78901 tctccatctt cacacttttc agtttcaaaa tgcttgctaa gttcttctac tacactttct
    78961 aaaagtatct tattatcttc aactattaaa accttcataa gtatccccta cctttatttg
    79021 tctatcttaa ctttatgaga ttttaagtca atatccacat tggctttttc ttttatatca
    79081 tcatacgtat atcccactat ttcaacactt tttgcctttg ttgaacacaa tatatctata
    79141 tctgtctctt ctgaaggctt taaaatctta tatgatggta cacgatttac tgttaaatat
    79201 tctccatttt cattaacttc tgctgtctta agaataatat ttcctaaatc ttttgatgat
    79261 gaatttttta cttttacttg atacgtaatt ccctcatttg attcatttac ttttttaagt
    79321 tctgatgtag atagcacctc atactgacta ctattttcta gcttaatatt attatttctt
    79381 atattaatag tattttcttt taaattaaca tacacaatct taccctctgc ctcatattca
    79441 tatgcataaa cttctacacc ctttacaaaa gttttatgcc cacattctat gtaagcaact
    79501 ttcccaggca ttaaagtcat atccaacaaa gccttactat ccgaagatat aattttttta
    79561 ttctcatcat attcattata tatcaattca acattggata tattaaatgt tgaattattt
    79621 tctacctttg ttgatgtatc tactttatca ccttcatcta tatttataat ttctgatttt
    79681 cctatattca atacttttgc atttccctca tctattttta tctcattttt atcttctgtt
    79741 tgaatatcaa ctgaatcagg ctgttcatct ttttcacatg ctgtcaacat aaaaataaat
    79801 attgttaata taatcattag agaaattgat ttttttacta ttttattcat attaagcacc
    79861 tcatatagta gtattttata gtagattttt atactttttc ataaattctt tcaatgcctg
    79921 tgtaagtatt tgatgttttt caaaattcga attactacat aatctttcaa aatcattcca
    79981 tatttcttta tctatacgta ttcttgttgt ttttaattca tctatgtgtt catcatctat
    80041 atgtacatct tttttattag atactttttt aggctttata ttgtaatctt ttacttctaa
    80101 ataccaatca tatacttcac aaagcttatc taaatcttct tgagttatat ttatttttct
    80161 atctttctta ggcttaacat tttgttttcg ctttgcattt tttaaacctg tatcattaaa
    80221 ctcaatttgt tcaacacttt tacttaaagc cttttcatta gaaatctttt ttttggtgct
    80281 tacttttttt ctattactta tagtattctt tttacttttt tcatactcct tagctttctc
    80341 ttcttccaag tttctattat ccaaactttt attataattt aattcgtctt ttaatatgta
    80401 tttacctttt tctgacttat atcctttttt atttaaaaaa gttcttaaag tactttgact
    80461 aatctttaga ttttgagcta tctctgcaaa tttaaatcct ttgctttgaa gttctaaaaa
    80521 tttgtcaatt ctgtcttcat tgttattcat taatattcct ccgtcaacat cttcttgtct
    80581 ttcttttcat acttcttatt atattcttct tttctaaatc tactctattt gattcaatta
    80641 ttttttgtag cattttatta taagtgaaat catctaaatt attatttttt atatagagaa
    80701 aagtttcctc ttcacattta ataaaacaaa ttgatagcaa ccatgccata cccattttaa
    80761 cataatattc ttcactttgt atattattac agtattcaaa tatttcttta atatgtttat
    80821 catcaacata atatattaaa aacataacta atgcaaatct aatttcccat ggattctttg
    80881 aataaacata ttttttaagt atatcataca tattttcttt atattttttc atagacttta
    80941 aaccagaaca aaacccatcg caaactgacc aattatcgat tttaggtata aatcttttta
    81001 catagtataa agtttcttca aaattactat ttatattgcc aattaccata ccttgtagcc
    81061 taacttcttc atagtatgta tcctctgcta cttctaaaaa ttccttccaa ttcccttggc
    81121 ttatttcttt tgataacttt cttaaattag gaactctaat acctattata ttttctgttc
    81181 caggtataag ctttttatta aaatctctat attttatatc ttttatagac atcatatatt
    81241 ctaaaagttc attataatcc aatttattcc attttcccct atcaaacatc atttaattgc
    81301 tccttaattc cttttttctt attgtaacat aaaactctac aaaaaaagct tctaactatt
    81361 agaagctttt tcaaaaacat aagaaacttt tcaattttaa atttaaacta aattaatgct
    81421 aatctcctac accaaagtct gtattattgt ataaaacttc tatatttgga ttttcatcca
    81481 agaatttata cttactaaca aaccatttca ctaactcttc atctcttttt atactagaag
    81541 aattatttat aaaaacattc actgtcgctt tttcaaaagt atttaggata atctctatat
    81601 ctttatctat catctctttt gtttgtcctt ttattccaat cataatacaa ggtgaatcaa
    81661 aatattcttt tacatcttgt ggagtcttaa aatttgcatt tttatttaaa atattatttc
    81721 taaaatcatt gtcaaaggtt tcaactccaa ttttaaatac cacaggaatt tcaaaatact
    81781 ctctcatttc cttaagccta tttttgtaag accaatgact ttctaaaaat aattttttta
    81841 tattcttctc ttttataata cactttattt tttctaaagt atccttaggt aattcaaaac
    81901 agcttccaga atttatgact tcaagaactc catatttccc agttacattt tttaaaaccc
    81961 ttagatttaa tttattcatc tcttcttcta aattagaatt atcatctata taatcacaaa
    82021 aagaacactt tccccatata caaggaaatc ctttaagcag aacaatttct ctttgatttt
    82081 tatttgttat ctcactatat ctatccattt tctatctatt ttcctccagt caatgatacc
    82141 tttaaagttt ttggaactgc atttaatcct aaattcacta aaacaactgc taacagctta
    82201 tctccataat cagtaaatac ttgggttaca aacacactaa aaacatctcc cagtcctaac
    82261 actttcaaga tttgcactat ataggatgaa cctgaagagg tcatacctcc aaataaaaat
    82321 gctgaaatta ttgaacttat tatagatgtt ggaatagcaa ataaaagtac tcctagtgga
    82381 gtttttaaac cccttaaaaa attcttttta aatgctattc cagcaagtaa tccggttgat
    82441 atttgaactg gtgcaaaata gagagaatac acatcaaacg taattccact tattaaactt
    82501 ccaaacacac ctgtaacaac agcgtattta ggtcctaaaa gtgaagctat cattatagtt
    82561 cctattgaat ctaagtatac aggtaatctt aatcccatag ctataaaagc gcctattata
    82621 tttatagaaa taccaaaagc tataagtgta atagttttta cacatatttt tcttttcaca
    82681 ctatatcact ccttccacag agtctataat gtcttcataa cctttaaaaa gcctctttaa
    82741 aaacatgtac ataaatttct tctcatcaac ttcatttaga acaattgcat taggattttt
    82801 tttatagaaa ttgaaagaat ccactataga ctgacccata gctattccat cttctacaac
    82861 ttctacatat gattcaaatc ctttacatat acttctgtct ataaagtacg ctactgctag
    82921 agggtcattt atcacacagc caattattcc ttcctgttcc caatggaaat caatataaaa
    82981 tctagttatt tcagttatat actttgccat cttcttatca agtctattta taaactcaat
    83041 aatattagga gtaagtacaa tttttctagt tacatctaaa cctaccatgt ggattttttt
    83101 agataaattc ttgtaaacat aatctgctcc atgtgggtct acccaataat taaactctgc
    83161 tactggagag caatttccat gaatcctaaa tgctcctccc atagatacaa actcatcgag
    83221 attttcaaat gctttcttat ctttaataag tgctttagct atatttgtaa gtggtgcaag
    83281 tgctattatt gatacttttt catgattatg taaagtattt attataaaat ccactgctcc
    83341 attttttgct ttagctccta caaccttttg ataaaagttt tctccaatac catcttctcc
    83401 atgtgtatct tgagctgtta caagttttct ttttagtggt gcttcttctc ctatatatac
    83461 tggaatattt agtgaagaac acatttgaag tgtttttagt gcattttctg cacctatatt
    83521 tgctggaaca tttccacaac atgtggtaat tccaattact tctagctctg gtgagtttaa
    83581 agccagaaga attgccaaag aatcatcaat tcctgggtca caatcaatta ttacttttct
    83641 cttttccatt ttttatcctc cttgatttgt ggtcgaggag aactacacat cttttttcca
    83701 ctttcaaaaa ggtgtgtcta agggtattaa ttatatactg ccactatata attccttagt
    83761 tttttatact tggagttctc gaacaagtac agatgtaaaa tcatattttt aggctactta
    83821 ctatagactc ttaaaaacta tagactgtta aaaaattttt aaacatctga tttaatagct
    83881 ataaaataaa ttttatagca taaaagaatt tattatattt taatgtatct tattaaagtt
    83941 tatttagaat tatgaaccaa ctttaataag atgtggcgca tttaaaccga ttattattat
    84001 acaataatat cttaaatatt acaattaata acattaattt attatccata aaaatatatt
    84061 aacttatatt atttaataat ttattgacag tattaaaatt aaattataca ataacagtgt
    84121 aaattaactt aacaccgtta agcaaagagg tgattatatg agtatcaaag aaagacgtaa
    84181 aaatgaaaaa gaagaaatga agaaaaagat tatggatgct agcatcgaaa ttataaacca
    84241 acatggatat gaaaatttat caataagaaa aattgctaca aaaatagaat attctccaac
    84301 tacaatttat ctttactaca aggacaaagc agagattatc agcgatatga ccaataaact
    84361 ttataacaca gtagaaagta atgctattga cattatgaat aattgctcat cactaccaat
    84421 agataaacaa atcatagaaa ttatgactag ctttataaaa actctttcta gtgaaccaga
    84481 gatggcaaaa gctatcatgc atagtagaat gaatattata tttgcatctg aaaatacaaa
    84541 caatactcct agcaataatg gtataaaaat gcttgataaa ttcctttcca ttggaattga
    84601 acaaggaata ttcaaaaaaa atatagataa aagctcatgg atgcttataa gtgcattgtt
    84661 aggattcgtt ttatgtgttg ttgaaaataa actatattct ttacataatt tttctcaact
    84721 tatagaaaat ttcttagata ttttagtggg aggactttac aatgaaaatt cgcaacaaag
    84781 ctactaataa aaagaaaaaa tatgtaaaaa tatctattgc tctattcttt gtatttatat
    84841 gcattattat tgtaattgta agcaacttaa agccagaaaa cttggtagta aaagatatag
    84901 atattaataa tgttaaaaat ggcatttata ctggaagtgc tgataataac ttggtaaaag
    84961 ctactgtgtc tgttgaagtt aataatggta aaatccaaaa tattaatatc ttaaaacacg
    85021 accatctttt aggtaaacct gctgaaaaaa ttacaacaag tattattaaa caacagtctt
    85081 tagatgtgga tgctataact tctgcaactt atagcagtaa tactatacga aaagctgtag
    85141 aaaatgcttt aagaaaggga gaataattat gaatactatt attatatatt caagtaaata
    85201 tggttgtaca aaagactgtg caaatatact aaaaaataaa ctatcagata atgtcactat
    85261 tgttgatatt aataataata ataaaattga gttatcaaaa tttgataaaa ttattattgg
    85321 aagttctata tatgttggtt cagtttcaaa aaaaatacaa gtgctatgta atgataatgt
    85381 agagttatta aacaaaaaac aagttggcat tttcctttgc tgtggctttt ctgaacaagc
    85441 agataaatat ttaaaatcaa attttccatc atccttatta gaaagtgcaa atgctattgg
    85501 aatttttggt agtgaagctc gattagaaaa aatgaaattt ttagataaac ttattatgaa
    85561 ggctgtttca aaaggtaatt atgacagttt tagaatatca caggataata tagataattt
    85621 tttaataaat cttaatagct aaaataaaac taattatttc tatgataaat tcttttattt
    85681 ataagtaata ttgctcaaaa tagtctttaa actttatcaa aattttattt ttcttagtga
    85741 aatctaatga aactagctct taatatatgc tttattaatc ataacaaaaa gagagtgtct
    85801 aatgaactaa aaagttcatt agacactctc tttttgtatg aaatcaaata tatttttatc
    85861 atttcaaaag agaaaaatac acttgtctct atgtttgaca cattctcttt ttataatata
    85921 atatctaatt taaaacctat ttcaaatatt gacatatact taaaccatag acttacaaaa
    85981 tcaattcata ttagcttaaa atataatctt tgttactcaa attcctatac acaaccatta
    86041 tttactttga tactttaaaa catcttccct attttttatt aaattttata ataatagtcc
    86101 tattaacgca aatactataa aaagagttta actttatcca ttaaataaat ttaaattaaa
    86161 acatatagaa atggaaggag aacaatttat gataaaacta atcggtatat tgatagttgt
    86221 aattggattt atacttaaaa ttgacacatt atttactgta ttattagcag gagtggcaac
    86281 aggaattgtt gcaggattag attttaatca aatttttaca attttaggag attcttttgt
    86341 ctcaaacaga ggtgtatcat tattcatatt aacactgcca gtaatcggtg tattagaaag
    86401 atatggttta aaacaaagag ctgtttcttt aatagaaaaa ttaaaaagac ttacaacagg
    86461 aaaagtactt actatataca tgatagctag acaaatagct ggtgctctat caataagaat
    86521 gagtggacat cctcaatttg taagaccact tgttaatcct atggcacaag ctgctggttt
    86581 aagtaatagt gatgaactaa aagaatcgga tgaagaagcc ataaaggcat tatctgctgc
    86641 atcagaaaac tatggaaatt tttatggtca aaacttattt gcaggtagta gtggagtatt
    86701 acttatagca tctactctaa ctcaatttgg atacaatgta actggactta atattgtaaa
    86761 ggctagtact attatggcag taatagcact tgtagtggct acaatccagt ttaccttata
    86821 tgataaaaaa ttaaacaaaa gtcataaaaa atagttttat ttaggaggaa taaaaatgca
    86881 aaattttata aacatatcat tggaaatctt ttacgcacta atgggatttt taatgattgt
    86941 tatagcatat aagtctttta ctaccataaa taacaataag aaatatggta catcattatt
    87001 ttggatactt atatcactgc cattcatatt tggtagattg attccagcca atataatagg
    87061 aataatatta atattatcta gtttattaac actttctaaa caagttgtat ttgcaaagta
    87121 tgaagaacca gatgaaaatt ttggaaaaga acaagcagac aaacttaaaa ataaaatatt
    87181 tataccatca ttaatattag catttgctgc agtagtagta gctatgagcc tttctaattt
    87241 tgataattct tctcaatttg caataggtgt gggttcaata attgcattaa tatcagccct
    87301 tataataact aaagcaaaac ctgctacatc agttcaagat ggctcaagat tacttcaaca
    87361 aatgggacct gctagtatgt taccacaact tttagttgca ttaggagctt tatttactca
    87421 ggctggagtc ggcgaagtta tttcaaccat gatatctggt gtagtccctg ctgatagcag
    87481 attatttggt gttatagctt atgtattagg tatggttata tttaccatga taatgggaaa
    87541 tgcatttgcc gcattttcag tcataacggc aggaattggt attccttttg tattgtctca
    87601 aggtggaaat cctgctataa ttggagcatt agcattaaca gcaggatatt gtggaactct
    87661 acttactcca atggctgcta attttaatat agttccagca gccttgctag aatgtaaaaa
    87721 tgattatatt gttataaaat atcaagctcc agttgctttg gtattaatta tagcccacat
    87781 attagtaatg tactttttag gattttaata taattaggag gtaaaataat gaaaattttg
    87841 ttaacaggat ttgacccatt tgggggagaa ctaataaacc cagctcaaga agcagttgaa
    87901 agggtcaata ataatataaa cggtgcagaa atcataaaga taactatacc aacagttatg
    87961 acaaaatctg ttgaagctat agataaagct attcaagagc acaatccaga tatagtaata
    88021 tcagttggac aagctggagg tagatttgac attacacctg agagagttgc tataaatata
    88081 gatgatttta gaataaaaga taatgaaggt aaccaggtta tagatactat tataaaagaa
    88141 gatggtgaac ctgcatattt ttcaaaatta cctgtaaaag ccatggtaaa acatatgaat
    88201 gaaaataaaa ttccagctag tgtttcaaac actgcaggaa cattcgtttg taatcatgtg
    88261 atgtatggaa tcctttatat gatagacaag aaatatccta atataaaggg tggatttata
    88321 cacatcccat atacaacttc acaggtaata aataaaaaaa atacaccatt catgtcttta
    88381 gaagaaatag taaaaggttt agaattagct atagaagctt gtattatata caaagaagat
    88441 gtaaaagaaa ttggtggtga aatttcataa taaatttttt agtattttat aaattaaaaa
    88501 tactaactat taatttaaat atagactgtg agtagattat tcaaacaatt ttactcacag
    88561 tctttttatg gcatctacag atacaaaatt aaggtctatt cctctctccc cactcacaca
    88621 ttgcatctaa aattggaatc agagattttc ccctttctga taaactatat tctaccttag
    88681 gaggtatttg aggatattca gtacgaataa tcaagttatc tgcttctaat tcttttaatg
    88741 ataaactcaa agttttatag gaaatagtat ttatataacg ttttaatgca ttatatctga
    88801 caacttcaaa ttctacaaga cagtaaagaa ttatcatttt atatttacca ctaatcagtg
    88861 aaagtgtata actaaatcct gtttcactta aatctgtatt tgatatacag tctatactca
    88921 tatattacac tctccttttg gttagtattg aacaaaaatg tgcgtacttg tttttagaat
    88981 aatttataat aaaattatag tgtaagaata attgaaagtc aattttataa taggaggtgt
    89041 atttactaaa aaaagagtta ttttaaatag gattctaaga ttagacattt ctatataaat
    89101 tgataatatt catgaaaatc ctattttata aaaaataata tctcttagaa aatctattaa
    89161 ataaaattca ttggaggaaa tttataatga aagttttatt gataaacggt agcccaaacc
    89221 aatatggatg tacttataca gcactaaatg agattactaa agtattgagt aaacacgata
    89281 ttaaaacaga aatactgtat ttaggtaaag aagcaatccc aggatgtatt agttgcgcat
    89341 cctgttttga aactggaaaa tgtattcgaa atgataaagt taatgaattg attgaagatc
    89401 tcgataatat tgatggtatt attattggtt ctcctgttta cttttctagt gcaactggtc
    89461 aattaacttc ttttcttgac cgtctatttt tcatagctgg aagtcgcatg gctacaaaat
    89521 taggtgcttc agttgtgtca tgtagacgtg gtggtgcaag tgcaacattt gaccaactaa
    89581 ataaatattt ttcaatcagc aatatgccta ttgtatcatc acagtattgg aatcaggtac
    89641 atggctttac tccagaggat gttatgaaag atgaagaagg attacagact atgcgaactc
    89701 taggagaaaa catggcatgg cttcttaagt gtatatcagc aggtaaaaaa gctggaatta
    89761 aagaaccaca atatgaagaa acaattatga ctaattttat aaaataaata aaaaatgcac
    89821 taatattaat taaaacaaaa cactaattta taaataaaat aagtataaat ataggataaa
    89881 aaacactaaa acagaggtat tgaattttat atcaaacctc tattttatta ttacattaat
    89941 aaccaaacca tatataacat catatatttc taaataaatt ataatattat attctaatgt
    90001 tattgaaatt acaataactg aatttctgct cataaattta aatattctac aaatctcatc
    90061 taaataacaa ttttaataga cctaaaacaa tcctcatatt gttcattttg tattaaaaat
    90121 atcacttaca atcaaaaacc atttattaag tatattccta agatatacaa tatatataca
    90181 tggattggat agtataaata aaataaatac ttcatactct tccctttttc tccattgtaa
    90241 agtaacatta aaggtagaga agcaatcatc atccattggt aattttgtaa aatagaattt
    90301 tttaaactat aatctccatt tgacattgtt gtaaatataa atatacacat caaaacataa
    90361 caaatactca aactgaactt tttacctcta cacaaataaa aaataatccc aagtataatc
    90421 caaattggtc caccttctac taaaaatggt actggtacca aaatcataaa taaagtaata
    90481 actctgttag tgactttaaa aagtaaagct actgtaaata ttcctaaaat tataggaatg
    90541 attatcatca ataatcctat aataaaatat ttaatttctt tctcttttct aaatttcttt
    90601 atgaactcta ttgcttgtaa ataaatcgct attaaaaata atgttgaaaa aatgttattt
    90661 ataattatag ctccttctgg atgtgaaaat acattattaa ttatttgatt tcctatagcc
    90721 ataataacag accaaatata caatctactt atatattttt ttctgttact agtgtgataa
    90781 aatccttcaa cagccatgaa tataaacagt ggtgctgata ttctgcctac ccaatgaaac
    90841 caaattggta tttgcattgt ttgtggcata aatgctgcta tatggtcaaa tgtcataaat
    90901 attaatgcta aaatcttaat agtaaaccca cttatacctt ttttaaaaaa atccatatca
    90961 tatctcctaa ttttgtttta tctctataat aatttttgtt cctattccaa tttcactact
    91021 tacataaatt ttacctttat gaatctctat tatttcttta gaaatagcca taccaagacc
    91081 tgaaccttta tgcatctcac ctgtattagt acctctataa tattttttaa aaatatgttt
    91141 caaatcactt ttgcttattc caattccatt atcttttatt ataatttcta tattatcttt
    91201 ttttacaatt tctacactta tcaaagttcc ttcgctatta tgaactattg aattaaatat
    91261 aagattggtt atagcccttc tgaataagat tgaatctaca tatacttcaa ttaaatcttc
    91321 attactttca aattcaatat tcctattttt atatctatta tcatttaaaa tatcaattat
    91381 tatatctctg actaaactga ctaaatttat ttttttcttg tccagaacta tagtattatt
    91441 ttttaatcga gtagataaat ttaaatcatc aactaaatct tttatatact tagacttatt
    91501 atatataatt tctgtatact ctcgtatttc atcttcttca aactcataat ctttgtcatt
    91561 aattatctct gcataccctt gtatagatgc tagaggtgtc tttatatcat gtgttatatt
    91621 tgccagccat tcctctctca actcttcatt ttcttttctc tcaacttcat ttactcttaa
    91681 agtatcagct aacatattta tatttttaaa aacttcttca tatatacctc tgtccttaag
    91741 atataaacta taatttccat tagccatagt ctcaatactc catagtacgc ttgaaattgg
    91801 ttttgtaagt tttctactaa ataaatatcc tacacctaaa gctaccacgc tatcaattac
    91861 tagtgttata atgataactt tatttaaagt ttttttaatg ttattttgag aataggttaa
    91921 aattattctt gatatatctc tactaggtat acctactatt atgtttagat gttttttgtt
    91981 taaatatttt tctagtacaa aattaacata ctttgtttct atatacttgt aattattcac
    92041 catttgaaag ggtgtatatt tttttggagt atcctttggc acatttactc cataaacttc
    92101 ctctcctaaa tcatttaaaa cctgtatcca ggaatttgat ttttctaatt tttcagctcc
    92161 aatcttagat agtttaaatt ctccatcttt ttcatataaa tctttttcaa aagaacgtgc
    92221 aaattcttca ggattatttc cagaatctac aactttaaaa aagctattag ttgaaatcac
    92281 atacaatata gatataatat ttataattac tactgatata gctacaaaca caattgtaaa
    92341 tataaaattt ctagtaatct tccacttcat attctaatct tcctttactg ctaatttata
    92401 tccaagacct tttattgtca gaatatattc aggctttgaa ggattatcct ctaatttttc
    92461 cctaattttt cttatatgaa ccattatagt attgtcaaat ccaacataat cttctcccca
    92521 cactttatcc catagttttt ctttacttat aatttgattt tgattatgtg caaataaaga
    92581 taggattttt agttcctttg cagacagtcc tatagatttt ccatctttta taagttctgc
    92641 cctactttca tttaatatat atgggccaaa tgatataatt ttttcttcat tcttatttag
    92701 atttttactt tcgttttgaa catcactaaa ataacttaat cttctcaaat gcgctttaac
    92761 tctaaaagcc acttccttag ggctaaaagg ttttgtaaca taatcatctc ctccaatcgc
    92821 tagtccaagt aacttatcta attcttcggt tttagctgat aaaaatatta ttggagaatt
    92881 ggaggttttt cttatttctt tacaaatatc ataaccttcg ccatctggta acataatatc
    92941 caatacaatc aaatcaggat taatactttt aaataattct aatccttctt ttttagtttt
    93001 tgcagtatat atattattaa ggccctcttt ttttaggaca gtttctaaaa gcttcaatat
    93061 ttctacttca tcatctatta ttaaaacacg attttccata aacaacctcc tgtaataatt
    93121 tacatatata ttagcatata ttttatctaa aattcattta tcttattttt aattaaacta
    93181 aaatataaat aaaattacta ttatttttag ttaaaacctt ttgcttgatg taaaattttc
    93241 atatgttatt ttagttaaca ctatcattaa tataattgag attactatag aaaaaactat
    93301 caaaatactt ggtacattat acctaaccat ttgttggctc atcataatcc aatttggagt
    93361 cactgacata aattttatag ctttatctgg tataaaacct acactaaagt atggaattgc
    93421 cattatcaat ccacctagta taaatggaat tacagccgat ttaaatatag atgaaagtgt
    93481 taagcctatt tgtgcaaata taaaagaagc aaaaatagta gtcaatataa caattatata
    93541 catttgtatt actgtaagat ttaaattact atttccaaag taccataagt tatgaatcgg
    93601 ttcatttaaa tttttaaaat caaaaaaact aaaacctcta attcctacta acaatataaa
    93661 agaaatatta ataatagata aaattaatcc attagctact agttttgata atactactga
    93721 tttttttccc tttttagttg tatttattaa acctgtcata ttagaatcat attctttaat
    93781 gtaatttcca gaagttatta taaacattat caaacctatt agaggtattg agccttctat
    93841 cttgtaaaat atatctgcat aagtatctaa aacatcaaac tttctaatca gaagaaatcc
    93901 caaaaatatt aaaaacagcc aaattatcca aacactcttt gattttaata tttttatcat
    93961 ttcagcttta actaaataca tcatttctac tacacctccc ttgcatcttc caaatcaaaa
    94021 taaaacatgt atacatcttc gaattttgct tgaactggtt gtatattatc cccacttgga
    94081 atatcctctg aaacaattct aagtactact gaatcaatat cactttgaat acttacaacc
    94141 ttatatttag attgtatatc atcaacttca cattcatttt taacttgaac attatatact
    94201 ttattttcca tgtgacttaa tatgtctttg tgtgttcctt tcattagaag tttgccatct
    94261 ttaatcatta ttgtttcctt tgcaactgat tctatatcgg aaattatatg agtagaaagt
    94321 attattatct tatctctaga catttttgct attaaattcc taaatctagc tctttcttgt
    94381 gggtcaatac ctgctgttgg ttcatcaaag actattatct tagggtcgtt tagtaaaact
    94441 tgtgctatcc caactctcct cttcatacct cctgaaaatt ttcctataga cttatttctc
    94501 acatcgtaaa gacctactaa atctaataat tctcctatct tactatttaa atattttccc
    94561 cttaaacctt ttaaagctcc aatatactgt aaaaattctt ttgctgtaaa atttttataa
    94621 actccaaatt cttgtggcaa atatcctaaa atatttctat aattagcatc cattttaaat
    94681 atatcctcac cattataaag tatctgacct tcatcaggtt ttatcaacgt tgttatttgt
    94741 ttcattaatg tagattttcc tgctccattt ggtcctagaa gaccataaac tccattttcc
    94801 agagttactg taatcttgtc gtttgctact tttttaccat atatctttga aagattttct
    94861 atttctaatt tattcatctt aactcccctt ttatctactt atataatctg attttattac
    94921 taaaaaacat aatgacatag cacctatcaa tattgccatc aaaagtccta ttgctatatt
    94981 gacaatgtct atattcactt taaatatcat aatatcacct agataatttc ctattatttt
    95041 attaaaacca aatatcaaat cataataatt tacatttgat acaactgaaa gtaatttttt
    95101 aggtaatata tggattaccg acattatctt agttatagat ataataaata taaaaaaact
    95161 tattgaagat attgaagatt tacttataaa agacccaaat atggctatca tggcccatcc
    95221 ttcaaacatc aaaagctcta tgcctatatt taatattaca tactttgtta tacttaaatt
    95281 agttttcaat gcaactacat tgtctactat tctaaaagat tctaagtctc cattaacagg
    95341 tactccttgt tgcatacaag ttataataaa tattcccatt aaataaacag aataaattac
    95401 taatggaact aataaagcaa caaatatttt agactttaat gcttttttct tctcttttga
    95461 tgatagtatg atatctttta ccgaagtaac gacttcatct acgtaaatat tggatataat
    95521 tatagatata atgattaaca ttcctacatt tataagtgaa tttgtaactc tatagttaaa
    95581 tactttccaa aaactaatat ccttatattc attcacactt agattatcaa gttttttctt
    95641 tgacattaat tcaatttttt tagaaaattc acctgtatct gtttgatttg aaaactgctt
    95701 taaaacatta atcttatttt gaaatttctc attacctatg tcgataccac ttctcgtatc
    95761 ttctatacat cctttttctt tatctatata ataacgttct gtttctaaaa caggcgtaat
    95821 aaagatacta atcattagta ttaacactaa tatccctaga gatataaaca tactcttaga
    95881 tttagccaat ttttttattt cccaatttac caatatattt ctcctcctaa atcattttaa
    95941 ttacacatat atattaaaac ttaaatctta tataaatata atactaacct taaataaagc
    96001 ttaaattatt ttataattta taggtgtgtt tattattgga gttacattta ttatttttct
    96061 gggaaattat acattttcaa ttatttttat tatttttgat atttttattg attggaaatt
    96121 ttattgttgt tcaaattgta gttattcttt aaatttaaag atggagtttt ttaagaatag
    96181 aacctactgt ccttattatg gaaagattat taaatagttg catataactt tatttatctt
    96241 gaatcttatt tttaaaaaca attataattt tagaatattt tctattctca aacaagcatg
    96301 ttgaataatg aagcatcttc tagtattata tacttgtaga ataaaactaa attggtaaaa
    96361 ctgggaatat ttaaccttaa ggagttaagt tatagaaact agtactaaaa aattttataa
//
LOCUS       DAEQJM010000010        90733 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.010, whole genome shotgun sequence.
ACCESSION   DAEQJM010000010 DAEQJM010000000
VERSION     DAEQJM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 90733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90733
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.010"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(65..1336)
                     /gene="serS"
                     /locus_tag="KRQ43_000904"
     CDS             complement(65..1336)
                     /gene="serS"
                     /locus_tag="KRQ43_000904"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH2741275.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKHKLNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            complement(2153..3757)
                     /locus_tag="KRQ43_000905"
     CDS             complement(2153..3757)
                     /locus_tag="KRQ43_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2741276.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGAANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVLDNNREFIKKYINR
                     FKVGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            4143..5069
                     /locus_tag="KRQ43_000906"
     CDS             4143..5069
                     /locus_tag="KRQ43_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH2741277.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTVLYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(5189..6187)
                     /locus_tag="KRQ43_000907"
     CDS             complement(5189..6187)
                     /locus_tag="KRQ43_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HBH2741278.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMTGKHVGRTVVDLEKI"
     gene            6291..6728
                     /locus_tag="KRQ43_000908"
     CDS             6291..6728
                     /locus_tag="KRQ43_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2741279.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            6814..7401
                     /locus_tag="KRQ43_000909"
     CDS             6814..7401
                     /locus_tag="KRQ43_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH2741280.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(7701..8321)
                     /locus_tag="KRQ43_000910"
     CDS             complement(7701..8321)
                     /locus_tag="KRQ43_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HBH2741281.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(8329..9096)
                     /locus_tag="KRQ43_000911"
     CDS             complement(8329..9096)
                     /locus_tag="KRQ43_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HBH2741282.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGVIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(9137..9958)
                     /locus_tag="KRQ43_000912"
     CDS             complement(9137..9958)
                     /locus_tag="KRQ43_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741283.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            complement(10315..12225)
                     /gene="phnW"
                     /locus_tag="KRQ43_000913"
     CDS             complement(10315..12225)
                     /gene="phnW"
                     /locus_tag="KRQ43_000913"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBH2741284.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNLWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIEFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(12504..13289)
                     /locus_tag="KRQ43_000914"
     CDS             complement(12504..13289)
                     /locus_tag="KRQ43_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH2741285.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(13506..13736)
                     /gene="dltC"
                     /locus_tag="KRQ43_000915"
     CDS             complement(13506..13736)
                     /gene="dltC"
                     /locus_tag="KRQ43_000915"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBH2741286.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(13755..14903)
                     /gene="dltB"
                     /locus_tag="KRQ43_000916"
     CDS             complement(13755..14903)
                     /gene="dltB"
                     /locus_tag="KRQ43_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBH2741287.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKHISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(14903..16417)
                     /locus_tag="KRQ43_000917"
     CDS             complement(14903..16417)
                     /locus_tag="KRQ43_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HBH2741288.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVIFN
                     FSDERNFGDINVIDMDKLNDIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(16538..17728)
                     /gene="dltD"
                     /locus_tag="KRQ43_000918"
     CDS             complement(16538..17728)
                     /gene="dltD"
                     /locus_tag="KRQ43_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBH2741289.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGINPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(18017..19036)
                     /locus_tag="KRQ43_000919"
     CDS             complement(18017..19036)
                     /locus_tag="KRQ43_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH2741290.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLHGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQAITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(19212..19751)
                     /locus_tag="KRQ43_000920"
     CDS             complement(19212..19751)
                     /locus_tag="KRQ43_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBH2741291.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPILVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(19852..20532)
                     /locus_tag="KRQ43_000921"
     CDS             complement(19852..20532)
                     /locus_tag="KRQ43_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBH2741292.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(20561..21850)
                     /locus_tag="KRQ43_000922"
     CDS             complement(20561..21850)
                     /locus_tag="KRQ43_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH2741293.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            complement(22313..23914)
                     /locus_tag="KRQ43_000923"
     CDS             complement(22313..23914)
                     /locus_tag="KRQ43_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH2741294.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDDLRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDNKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGIIKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(24025..24702)
                     /locus_tag="KRQ43_000924"
     CDS             complement(24025..24702)
                     /locus_tag="KRQ43_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741295.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(24715..25410)
                     /locus_tag="KRQ43_000925"
     CDS             complement(24715..25410)
                     /locus_tag="KRQ43_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH2741296.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(25462..26661)
                     /locus_tag="KRQ43_000926"
     CDS             complement(25462..26661)
                     /locus_tag="KRQ43_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HBH2741297.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDICRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARNLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(26922..28967)
                     /locus_tag="KRQ43_000927"
     CDS             complement(26922..28967)
                     /locus_tag="KRQ43_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2741298.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNILIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILNSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(29378..30187)
                     /locus_tag="KRQ43_000928"
     CDS             complement(29378..30187)
                     /locus_tag="KRQ43_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2741299.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTFVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(30271..30804)
                     /locus_tag="KRQ43_000929"
     CDS             complement(30271..30804)
                     /locus_tag="KRQ43_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH2741300.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGLNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(30931..33006)
                     /locus_tag="KRQ43_000930"
     CDS             complement(30931..33006)
                     /locus_tag="KRQ43_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741301.1"
                     /translation="MLKGLSFRNARRQAGKYLIYWCSLIGSVALIYAFNALIFSDVMQ
                     ELSSILNNGGSDEFSYMIIIFSFIITFILGWFVSYMMNFILKKRSREISTYMILGVDK
                     KQIVKMLFIENLLLGASALIVGWILGIFVSKVLESIVINMFHGKYSLSPDFSLKAAGM
                     TFLYFCIIYLIAQLKSNKKLVKMKLINLLNYDRYNENVLIHQTKTKSIMFCVSVLCGG
                     MGIFFFSIPSGRLTDVFLGLLLIVFCLIVLFMGFGSIAQNMFEKGMNWKYKKSHLFLY
                     RLLASKINGISIIMGIIATLFTVSIACIGIANSFYSVMNKSVDLQQFDVSIFHPNESY
                     DFSSYEGYLSETKGVKKDYSYTLYTEEKTSFMKVRNNILSKYLKDIGRDLQYKDYTFA
                     ENQFDTFMKYSDYNILRNMLGLNPIKMDKNQFIIHCMPYLADAYKNYIGEKYKLTISD
                     KDLSIAGIYIENFSQYGGYGNGQEYIIVIPDYLIDNMKPLYSLYVAITSEPLDSAYFT
                     EFQKKFDTLENLNSGVVVAGNQGFVSKLRYDNKDYISGKYAMQSTGQAIILILPLFYL
                     ALIICIIGTVILSIQLLSENNIIIKHYGMLRTLGMIDSEVIKILKKHVCLYFSIPLIP
                     AVIFGGILVSVFSYNMFNISFDAPVFFNIQIPILHAVAITLINFVVIYCIYVFITYVA
                     LRKEILHIK"
     gene            complement(33009..33755)
                     /locus_tag="KRQ43_000931"
     CDS             complement(33009..33755)
                     /locus_tag="KRQ43_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741302.1"
                     /translation="MLLRVENIEKYYGNQKILTKALNDVSFQINTGEFVSIMGTSGSG
                     KTTLLNCIATIDTVSAGKIYLENQDITELSEENLTVFRRDNLGFVFQDSNLLDTLTLE
                     ENIALPLTIKKVSPVEITNSVYNIATQLKIEEILSKFPYEVSGGQRQRCAVARAVVTE
                     PKLILADEPTGALDSNSSKTLMELLETINTILEATILLVTHDAISASYTERILFLRDG
                     KIFNELRKGEKSRLTFYHEILDALSLMGGD"
     gene            complement(33769..34164)
                     /locus_tag="KRQ43_000932"
     CDS             complement(33769..34164)
                     /locus_tag="KRQ43_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HBH2741303.1"
                     /translation="MKKRILTILCVVLVLFISITGLDSMGFFSRSIIPLRSEYASFIR
                     KNGTITEVKFTGPFNHNNIDLNKNVEDTNKNGDDNELTIKYDIEVKKSLISSNEPTIQ
                     IQDSKESIYVYILNFSDKTIIIKNGKIVD"
     gene            complement(34277..35299)
                     /locus_tag="KRQ43_000933"
     CDS             complement(34277..35299)
                     /locus_tag="KRQ43_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH2741304.1"
                     /translation="MRFCNFLQDKVLVILLNICCAISLVLYLHLIGIGQGELTLLIAA
                     WVAILFCWICFCYQKQKKEIIKLRRIVDELDKKYLFIEMIEKPTSNIEREYYNIIRLS
                     LKSMTDHVSQIHREMYEYRQFIEQWVHEIKHPVTTSELICENYKNEHTRKIRFQMEEI
                     ERHIERALYYARLGHVEKDYLISEITLKSIVEEVLAKNKLLLIQNNIHINIQDLEYSV
                     YTDKKWIVFILNQIIINSVQYKSDSAEISFFAIKEDKSVKFTIKDNGIGIKESEIYRI
                     FELGFTGSNGRTTNNSTGIGLYLCYELSKKMGIDIDVSSSLGEYTAITLNFPINTAIN
                     MQKQCN"
     gene            complement(35296..35967)
                     /locus_tag="KRQ43_000934"
     CDS             complement(35296..35967)
                     /locus_tag="KRQ43_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005924879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2741305.1"
                     /translation="MILTNILIIEDDVFICKELMQFFENNGYSTQTLDTNNCDVLQVI
                     QESTPDLILLDINLPNIDGFSLCRQIRNCSTIPIIFITARDSAIDELNGLTMGGDDYI
                     TKPYNLPLLLARVKNLLKRVDSSDKQKIKYREIILNLISATVEYQNAVIELSRTELKI
                     MYYLFQNVGSIVPRIDLVEYLWDNHIHIDDNALSVNITRLREKLRGIGITDLIITKRG
                     MGYRI"
     gene            complement(36053..37402)
                     /locus_tag="KRQ43_000935"
     CDS             complement(36053..37402)
                     /locus_tag="KRQ43_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH2741306.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNRANSIEEIKPCEISKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIDKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEVIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(37414..38796)
                     /locus_tag="KRQ43_000936"
     CDS             complement(37414..38796)
                     /locus_tag="KRQ43_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH2741307.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNRDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            39040..40254
                     /locus_tag="KRQ43_000937"
     CDS             39040..40254
                     /locus_tag="KRQ43_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH2741308.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIKLYGNKCDYAKRDTLLYTANKLEIKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            40431..42344
                     /locus_tag="KRQ43_000938"
     CDS             40431..42344
                     /locus_tag="KRQ43_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2741309.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDNIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            42615..43589
                     /locus_tag="KRQ43_000939"
     CDS             42615..43589
                     /locus_tag="KRQ43_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH2741310.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            43610..43885
                     /locus_tag="KRQ43_000940"
     CDS             43610..43885
                     /locus_tag="KRQ43_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH2741311.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            43898..45061
                     /locus_tag="KRQ43_000941"
     CDS             43898..45061
                     /locus_tag="KRQ43_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH2741312.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGTEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            45398..47678
                     /locus_tag="KRQ43_000942"
                     /pseudo
     CDS             45398..47678
                     /locus_tag="KRQ43_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
     gene            complement(47773..49113)
                     /locus_tag="KRQ43_000943"
     CDS             complement(47773..49113)
                     /locus_tag="KRQ43_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2741313.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILIGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVTYYFIR
                     GKSTLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     IVQVFPEVFVGIFNKDSDLMDIAVRGISINLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(49125..49907)
                     /locus_tag="KRQ43_000944"
     CDS             complement(49125..49907)
                     /locus_tag="KRQ43_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741314.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(49922..50944)
                     /locus_tag="KRQ43_000945"
     CDS             complement(49922..50944)
                     /locus_tag="KRQ43_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH2741315.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(50950..51963)
                     /locus_tag="KRQ43_000946"
     CDS             complement(50950..51963)
                     /locus_tag="KRQ43_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH2741316.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(52091..53029)
                     /locus_tag="KRQ43_000947"
     CDS             complement(52091..53029)
                     /locus_tag="KRQ43_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2741317.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWSQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            53299..53763
                     /locus_tag="KRQ43_000948"
     CDS             53299..53763
                     /locus_tag="KRQ43_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741318.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTGKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(53875..54192)
                     /locus_tag="KRQ43_000949"
     CDS             complement(53875..54192)
                     /locus_tag="KRQ43_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH2741319.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(54205..54936)
                     /gene="chbG"
                     /locus_tag="KRQ43_000950"
     CDS             complement(54205..54936)
                     /gene="chbG"
                     /locus_tag="KRQ43_000950"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBH2741320.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVVEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(54962..56272)
                     /locus_tag="KRQ43_000951"
     CDS             complement(54962..56272)
                     /locus_tag="KRQ43_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH2741321.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNNGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLVAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(56349..57662)
                     /locus_tag="KRQ43_000952"
     CDS             complement(56349..57662)
                     /locus_tag="KRQ43_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2741322.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(57684..57995)
                     /locus_tag="KRQ43_000953"
     CDS             complement(57684..57995)
                     /locus_tag="KRQ43_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2741323.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(58195..58899)
                     /locus_tag="KRQ43_000954"
     CDS             complement(58195..58899)
                     /locus_tag="KRQ43_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2741324.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYMTRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(58994..60355)
                     /locus_tag="KRQ43_000955"
     CDS             complement(58994..60355)
                     /locus_tag="KRQ43_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2741325.1"
                     /translation="MKDRINLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAIYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     MSE"
     gene            60854..61999
                     /locus_tag="KRQ43_000956"
     CDS             60854..61999
                     /locus_tag="KRQ43_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH2741326.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQDVINKKYIVYRIGGDEYIIILKNLSHKEINSIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKKKINK"
     gene            complement(62089..63807)
                     /locus_tag="KRQ43_000957"
     CDS             complement(62089..63807)
                     /locus_tag="KRQ43_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH2741327.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(63812..64801)
                     /locus_tag="KRQ43_000958"
     CDS             complement(63812..64801)
                     /locus_tag="KRQ43_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2741328.1"
                     /translation="MSYLKINNVFKSYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(64897..65946)
                     /locus_tag="KRQ43_000959"
     CDS             complement(64897..65946)
                     /locus_tag="KRQ43_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH2741329.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTYNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(66223..66891)
                     /locus_tag="KRQ43_000960"
     CDS             complement(66223..66891)
                     /locus_tag="KRQ43_000960"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBH2741330.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(66897..68270)
                     /locus_tag="KRQ43_000961"
     CDS             complement(66897..68270)
                     /locus_tag="KRQ43_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBH2741331.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(68267..70045)
                     /locus_tag="KRQ43_000962"
     CDS             complement(68267..70045)
                     /locus_tag="KRQ43_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBH2741332.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(70162..70485)
                     /locus_tag="KRQ43_000963"
     CDS             complement(70162..70485)
                     /locus_tag="KRQ43_000963"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBH2741333.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(70472..71449)
                     /locus_tag="KRQ43_000964"
     CDS             complement(70472..71449)
                     /locus_tag="KRQ43_000964"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HBH2741334.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(71464..72027)
                     /locus_tag="KRQ43_000965"
     CDS             complement(71464..72027)
                     /locus_tag="KRQ43_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HBH2741335.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(72079..72570)
                     /locus_tag="KRQ43_000966"
     CDS             complement(72079..72570)
                     /locus_tag="KRQ43_000966"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBH2741336.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(72573..74498)
                     /locus_tag="KRQ43_000967"
     CDS             complement(72573..74498)
                     /locus_tag="KRQ43_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBH2741337.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(74500..74811)
                     /locus_tag="KRQ43_000968"
     CDS             complement(74500..74811)
                     /locus_tag="KRQ43_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741338.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VRKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(75441..75716)
                     /locus_tag="KRQ43_000969"
     CDS             complement(75441..75716)
                     /locus_tag="KRQ43_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HBH2741339.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DITVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(75831..77240)
                     /locus_tag="KRQ43_000970"
     CDS             complement(75831..77240)
                     /locus_tag="KRQ43_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBH2741340.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     SLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGGIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(77610..78272)
                     /locus_tag="KRQ43_000971"
     CDS             complement(77610..78272)
                     /locus_tag="KRQ43_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741341.1"
                     /translation="MIDVSIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(78526..80745)
                     /locus_tag="KRQ43_000972"
     CDS             complement(78526..80745)
                     /locus_tag="KRQ43_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH2741342.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYALNQDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKITISVPLLNNDK
                     VVGVLYCTYNINTLMKLINVSFYENNSISYVVRNDGTIILHPQEDSLSKNIYKLLKQD
                     NDIREINRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSEQIINRAIYAVLFIILIFIAIIFYIIYIKKSNEKEILSLAYEDKVTHIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGKNKRIRKIDSIRNNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LSEWKKQGKKIVPVSINLSRVELYQPDIVKFINKTIQMYNLSSDLIEIEITETVAINE
                     LNILKNVLNELRKYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLNGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(81021..83675)
                     /gene="adhE"
                     /locus_tag="KRQ43_000973"
                     /gene_synonym="adhC"
     CDS             complement(81021..83675)
                     /gene="adhE"
                     /locus_tag="KRQ43_000973"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH2741343.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYTQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDESADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDNAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRSPGKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEEPKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            84179..84379
                     /locus_tag="KRQ43_000974"
     CDS             84179..84379
                     /locus_tag="KRQ43_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741344.1"
                     /translation="MKKLKTISIFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            complement(84587..85177)
                     /locus_tag="KRQ43_000975"
     CDS             complement(84587..85177)
                     /locus_tag="KRQ43_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HBH2741345.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(85180..86055)
                     /gene="dpsA"
                     /locus_tag="KRQ43_000976"
     CDS             complement(85180..86055)
                     /gene="dpsA"
                     /locus_tag="KRQ43_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HBH2741346.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEVGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            complement(86131..87522)
                     /locus_tag="KRQ43_000977"
     CDS             complement(86131..87522)
                     /locus_tag="KRQ43_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HBH2741347.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEQLGKQIS
                     LGENISILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNLYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEYTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIRGGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIVNIGGFKVSSAKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            complement(87526..88662)
                     /locus_tag="KRQ43_000978"
     CDS             complement(87526..88662)
                     /locus_tag="KRQ43_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBH2741348.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CNLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIERADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     PILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKTKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIERYNIFGGALAYGH
                     PYGASGAIITLHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            complement(88694..89239)
                     /locus_tag="KRQ43_000979"
     CDS             complement(88694..89239)
                     /locus_tag="KRQ43_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBH2741349.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            89563..90342
                     /locus_tag="KRQ43_000980"
     CDS             89563..90342
                     /locus_tag="KRQ43_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741350.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMSSEVSSIRCCNCDELLEDITLNKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
BASE COUNT        30295 a        15590 c        10487 g        34361 t
ORIGIN      
        1 ttatattaat tattttttat tacttctata ttattgtatt gcttaaaaat acataattta
       61 actcttattt aataacagaa actcccatat atggtcttaa aacttcagga acaaccacag
      121 aaccatcttc ttgttgataa ttttctaata tagctgcaac acttcttcca atagctaacc
      181 cagagccatt taatgtgtgt acatattcag ctttagaatc tttatctctt ttaaatctta
      241 ttcctgctct tctagcttgg aaatcttcgc agtttgaaca agatgaaatc tcaacatacc
      301 tattgtaact tggcatccaa acttctacat catatttaaa agaagccgta aatcctaaat
      361 cacctgtaca tatctttact actctataag gcagattcaa taattgtagc atagtttccg
      421 cattgttagt aagcttttct aactcattgt aagattcttc tggtgcaact attttaacca
      481 tttctacttt gttaaactga tgctgtctta ctaaacctct tgtatctctt ccagcagaac
      541 cagcttctga cctaaaacat ggagtataag ctgtataatt tattggtaat tgttcaaatt
      601 taagtatttc attagcatgt atattagtta aaggaacttc tgatgttgga atcataaaat
      661 agtccagacc ttctatttta aacatatctt cttcaaactt aggtaactgt cctgtaccta
      721 aaaaactatt tctatttgcc ataaatggtg gaatgacttc tgtatatcca tttacttttg
      781 tattcgtgtc taagtaaaaa tttaataatg ctctctctaa tctagcaccc aatcctttgt
      841 aaagagtgaa tcttgaacca gttattttac tcgctgtttc aaaatcaagt atacctaatt
      901 ctgttccaat ttcccaatga gccttagatt caaaatcaaa ggtagtagtc tttccccaag
      961 ttcttacctc aacattatct tcatcagttt caccttgtgg tacttctgga tgtggtacat
     1021 ttggtattct cattaatagg tattccatct tatcttctac ttctttaaga ttttggtcta
     1081 ttaccttaat tttatcagat aactctttta gtttaatctt ttcattttct acatctttac
     1141 cttcttttat aagatttggt atatttttag atgctgtatt taatttatgt ttcataactt
     1201 caacttcttg aagaatcttt cttctttcat catctaactt aactacttca tcaaggttaa
     1261 agtctttttc gccccttctt tccattgctt tttttataca atctaaattt tctcttattc
     1321 tttttatatc aagcattttt tcctcctcag tacctaagat tggatttatc tcttaatctc
     1381 aaataactta gataatatac tttatgcttg aggttaagaa acctttttct ttatccgaac
     1441 ctgttatttt tattttattt atattttact cacttttttg tccattgtca aattatattt
     1501 aattaaataa atgaaattta attttaggag aatattgcta gatttaactt cattataatt
     1561 atatctattt tgctaatcaa ttatctattt tgactttttc tttatcaatc ttgtatagtt
     1621 attaactttt atataaattt ttttatatta taacatagtc ctatatatct attatttgga
     1681 tagaattatt ttttaaatta gaattatttt aatgaatgct tcaagtaata ggtatgaaat
     1741 tgaatctttt agaactgctt ataaaaaata ctcaaagaaa aatagtaatt ttctcagatt
     1801 cacaatatat tttatatgaa atgttataag gtaatctatt taataaattt aaatttgcta
     1861 ttatagattt agttccaaag tcttactgca aagtaatata catagttttt taataaacta
     1921 ataagtgcaa ttaataacta cttaattgtt taatatagta catagataac tttaataaat
     1981 cgacagttat ttaaaaaggt agaatcaata aaattatact tataaatctt caatacaata
     2041 attaaaattt aataaaaaat ataattgttg atttaactgt aatcttattt aattctacct
     2101 aacttattat ataaaactat tttttataga ttataaaata tctaactttc atctacttca
     2161 aagaatacaa tacttctcct tctcttatag tctgcaatac tttaatatct tttattttca
     2221 tagggtcgat tgtaagtggg ttttcatcta atattatcaa attagctaat ttaccttctt
     2281 taattgaacc ttttttatct tcttcaaaat attgatatgc tgcatttata gtaacaccct
     2341 ttaaagcatc taatgggctt atcttttcat tctctcctat ttgtatacct ttttttgtaa
     2401 ttctatttac agcacaccat actgtttcca gcatattagg tgctattact ggtgtatcct
     2461 gatgaagagt gtaaattaat cccttttcta tagttgtttt aagtgggcta atcttaaacg
     2521 ctctatcttc tccaaggttt ttgatatgaa tatcacccca ataatatgtg tgagctacaa
     2581 agtatgaagg tatcatattt attactttca tatcatcaat ctggtctgct cttactgttt
     2641 gagcatgtat cataactggt cttatattat tttcactact ttgctctttt aagtttaaaa
     2701 ctttctcaaa cgcatctatc aactggtctg ctgctgcatc tccattacaa tgagttaaga
     2761 gttgcatctt ttcttttagt gaaatatcta taaacttttc tacttcttca tctttgtata
     2821 taggatatcc acaataacca tcatctgaat tttcatatgg tctactcaac catgctgtct
     2881 taccttgtgg agaaccatct aagaaaatct tataacctcc tactttaaat ctatttatat
     2941 atttttttat aaactcccta ttattatcta atacagactt actttttttc aaatttacat
     3001 atcctacaac atccattttt aatttatttt gatttgccat tgcttttaaa atgttaaatt
     3061 gattttcttc cattaaacct tcttgagctg ttgtaatacc atagcttaga tatatgttct
     3121 gtgctttttc aattgaatta aaaatctcat ttgatgatgg ttgttttatt ttagatgcta
     3181 cattaaaaaa tgcattttct tctaaatatc catttggttc ttcactgcct tctactctac
     3241 ctatatgtcc accttctggg tcacgtgttt cattggtaac accaagctgt tttaacccca
     3301 atgtatttgc agctcccata tgaccagaag catgtgaaat tagtattgga ttttctgaag
     3361 atgcactatc gagtacactc ttatctggat gcttattttc ttctaaaaaa ttattatcat
     3421 atgaaaatcc aattatccag tctccttttt ttatattatt cgactctttg aaatcctgta
     3481 ttttttttac tatgtcttta aaactggttg catcttctaa aggaactagc tttagagtag
     3541 tagcaaaagc tatcaagtga ctatgtgaat ctataaaaga tggcatcaat gtcttacctt
     3601 gtaaatctat aatttctgta tctttatttt tcaaagcaaa tacttcttct tttgttccta
     3661 tcttttttat tattttatct tttataagaa tagcatctcc acatattgaa tcttccattg
     3721 tgatgatatt tccattgtaa taaatttttt ctttcataaa attctcctta cgttgtctac
     3781 tttaataaat ttttttcatt attttctgct taattatatt atcttcttta taaacttttt
     3841 ctttagagtt taatcatata aaagttttat ttttaattat tgtttgccaa gaagtaaata
     3901 ctattcattg taaataagac aaattaatag gctttatact aattgaaaaa atattataag
     3961 ttgttaaatt taaatatcta aactcaatta tatctgtaca attgtaattt tttaaatcat
     4021 gatgtattat tttaaatata cagttacatt attattcaca atataagtat cttagttctc
     4081 aaataacatc tcatgtaatc tattcaatgc aaaaaattta aatatttttt aggaggtttt
     4141 ttatgagcaa ggaaaataaa aatgtaagaa ttgctgttgt ccaggcgtca ccagtcataa
     4201 tggatttaga aaaaactgtt gaaaaagcat taggattaat taaagaagct ggtagaaaag
     4261 gggcaaatat cgtagttttc cctgaagcat tcatacctgc atatccaaga ggtctttcat
     4321 ttggatttgt tgttggaagt agaacaatgg aaggtagaga agattggaaa agatactatg
     4381 ataattctgt accagttcct agtgctacaa cagatttatt aggaaaagca gcacaagaag
     4441 caggagtata tctatcaatg ggtataacag aaagagatgg taatgatata aattgtaccc
     4501 tttattgcac aaacttattt ttctctccag aaggtaagct aattggtaaa cacagaaaac
     4561 ttaaacctac aggaacagaa agatgtattt ggggagaagg agatggaagt actcttacag
     4621 tagttgatac tccatatgga aaaatgggtt cgttgatttg ttgggaaaat tatatgccat
     4681 tagctagaac agttctttat gctaagggtg taaaacttta catagcccct actgcagatt
     4741 caagagaaga gtggcaagca actatgaagc atattgcttt agaaggaaga tgttttgtaa
     4801 ttggatgcaa tcaatatgtt gaaaaaaata tgtatccaac tgaccttaac tactataagg
     4861 agctagatgc agaaccagaa attatgtgtc caggaggaag ttgtatagtt gacccttttg
     4921 gaaaatatgt agcaggtcct attttcaata aagaagaaat gctaatagct gatttagacc
     4981 tagaaaaaat agtacttagt agactagatt ttgattcaga aggtcactat tcaagaccag
     5041 atgtatttga attaattgtt catgaataat ctttttacac aaacatctac ataaattttt
     5101 ttacataaaa aaatgagata ctcataagta aatttcaagt atctcatttt tgcttaaaac
     5161 ctataatcct aattataaat ttattcgcct atattttttc taaatcaact actgttcttc
     5221 caacatgttt tcctgtcatt atcgaatcta tactatcatt taactcttcc aatgatacta
     5281 catttaccat atcatctaaa tcatctaatt tccattcatt tgataataaa tcccatattt
     5341 ttaatcttaa gttcattggg caatccacag aatctatacc atataaagta attcccttta
     5401 agataaatgg atatactgaa cttgtaaaat caactcctcc tgcattacca caagttgtta
     5461 ctgctccaca ataattagtt gtctttattg ctgttgctag agtatttcct cctactgtat
     5521 ctattactcc agcccatctt ggtctaagca gaggtcttcc tgagttatca tccacttctg
     5581 acctatgtat aacatcttta acacctaagt ttagtaatac ttctttttgt tcttctaatt
     5641 ttcctgttga aactacaact gaataaccta atttaatcaa tattttagtt gcaattacag
     5701 caactcctcc agtaccacca gtgactaata catctcccat attcttgtct acagaatcta
     5761 taaatttata cacagataaa gctgctgtaa accctgctgt accataatcc attgcttctt
     5821 ttagtgaaag atttttagga agtttaacta cccaactaga aggaactctt atgtattctg
     5881 aaaaaccacc agaagtattc attcccaagt cataacctgt tactaaaact tcttctccaa
     5941 ttttaaaatc atcacaacta ctagattcta ctataccaga tgcatcaatt cctggtgtat
     6001 gaggatactt tctcgtaaca cccttattac catttgcaga aagtgcatcc ttgtaattta
     6061 gagaagaata ttttactttt attagaactt cgccttctgg caatgtatct acttctcttt
     6121 caactatatt tcttctaaaa tttccttctt cttctgtaat atatagtgat ttaaattttt
     6181 tattcataaa tttcctccca atacatttag ttttatgtta aactaattat agtttataaa
     6241 tagttttatg tcaaactaat ttaaatagat taaagattgg agaataattt atggaagata
     6301 aatatattgt acatttcata agtaaaacaa aggctagtat gattaaattc attgaaaata
     6361 aactcagtaa aaatggttta ggtgagttaa tacctactca tggaaatatt ttaactgcac
     6421 tttatgaaaa taatggaata cttacaatga aagaaattgc agctaaaata ggaaaagata
     6481 aatccactgt tacagtgttg gttaataaac ttataaacct aggatattta gaaagacaaa
     6541 aatgtacaaa tgacaaacgt atcacgtata taaagcttac aaaaaaggca ctgcttatag
     6601 aagatacttt taatagcatc tcaacacaag ttaaagagac agcataccat aatattacag
     6661 aaaatgaaaa acaagaattt cttagaattt taaaaaaaat taatgataat tttaaaaatg
     6721 ctgactaaat tgagcataat tatatctcct attggaataa taaataaaaa gaatcaaata
     6781 ttgtaaaaat ttattatgat agagaggtag aatatgaatt taaaagatag taaaactaaa
     6841 gaaaatttat taagagcttt tgcaggtgag agtcaagcta gaaatagata caatatttct
     6901 gcatctgtag caaaaaaaga aggattatat ataatagagt ctttatttaa ttacactgct
     6961 gaccaagaaa aatcacatgc aaaacaattc ttttctaaat taaaagaatt tgctggtgaa
     7021 aatataagta tatcaggagc ataccctgta gatttatatg acaagacagc acaacacctt
     7081 aaagctgcac aacataatga gcttcaagag tgggatgatg tatataaaaa ctttggaaaa
     7141 acagcacgtg aagaaggatt tgaatctata gctaagttat ttgaaaatat agctgaaata
     7201 gaaaaagttc atggtgatag atttggtaga tatgctactg atttagaaga aggtacttta
     7261 ttcagaagaa atgaagatat acaatggata tgtacacatt gtggccatat acatataggt
     7321 aaagaagctc caaaagcttg tcctgtatgt cttcatccac aaggatattt cttagatttt
     7381 aaaaactcat tatttgaata aactaaggca ataattctat ttaaacaatt tactatattt
     7441 atatcaagta tttttataaa tactgtatta tcttaataac aataaaatga accattgata
     7501 ttactataag tagaaaatgt agtttaaata caatttatag taattcatca tggttcattt
     7561 tattatttac taatccctat aacctactta aatctatctt taacttttac atactcacat
     7621 aaaatcttat ctttaaacta aatatttaaa taaagtgtat tttaagtaga ttattataat
     7681 acattatata agataataca ctatgataac tttatactta tatcatttat ttcttttgtc
     7741 aagtcaatct caataatctt aactacatct ttttcaaact ttactttttt ataatccaga
     7801 catcctacta cgaatggaac tccaaacttt ctaaacaaat aaatctttcc actttcattg
     7861 tatattgatg taaaattttc ttctattata ttcactatca attttaactc ttcaaaagtt
     7921 attatagatt taactaaaaa cttctctatt atgctcaata taagcagttc ttttttacct
     7981 atgctttgct cttttttata taaattttga aatatttctt tggtataatt acatataact
     8041 tctttactga gaataaaatc aatgtcaaat tccttattaa tatccttttt cataaacata
     8101 tttgcaatat catcaagaga agtctcttct ttcatagaca atattaactc tattctttct
     8161 agtattttat ctcttggaaa gaaagtctct tgacctgtaa aagctgattt ttttataaac
     8221 cattcctctg gtattatgtt ttttcttttc catctatata attgaccata agatatatta
     8281 gttttgctca ataaatcttt cttagatatt aattcttcca taacttttct agcccacctt
     8341 tatactgttt tttacagtag aattatctga aactgataaa ttatcactgt attcaatatt
     8401 tccaacgtca caattatcta ctagagatat gcttttgcct cgtatatctt ttattgatgc
     8461 atcttctaat tcaatagtat ctccctctat caaattacat ttaaactttc ctgaaaaaat
     8521 attaatgatt ttaattaatg aaaaagcatc tttgcttctt cctattttta tattagttgc
     8581 ccctatctct ttacaataag aacctcctcc tgaataaaca tatatatttt ctccatttaa
     8641 aagaccatca cattttatta ctccatatac ctttatatct tcacattcta tatttgattt
     8701 atttctcatt tcgccataga tttttatatc ttgtgcatac atattttcat ttacacttaa
     8761 ttgtcctctt attgtaacat tattacattt aagtttgcca tccactttct gttgagcagt
     8821 tataactaag tcatctattt ctgcatctcc ctctatatta agttgaccat tcactcttac
     8881 acgctctgct ttaagattgc ctcttataat agtttttccg ttaacaacaa aattttttat
     8941 attgatgtca ccttcaaatt ttgcatctcc aaggactttt acttcgttac ttttaacatt
     9001 tccttttgat ttagaacttc ccacgatttt tatattttca tactcaccac tacttataaa
     9061 gccttctcca agtattttta tagacccttt ttccatatta ttacctcatt ttaaatttta
     9121 tttttaaacc tatttattac ttatccttct ttaattttat tttttcactt atattcttta
     9181 tttcaccaac tattgaatct tcatcaatct ctatactttc actgtactcc aaactttcta
     9241 cataacatcc cttgcctatt ttaatatttt ttcctcttac aactttgact tcactatttt
     9301 ctaagcttat ttcatctgct tctataatat ttgcaaacaa tttactttct gtatactttc
     9361 taattgataa tagacctaaa cttattaaat ttgaagacac tttttcaaag ttgatatgct
     9421 ttttttctag catacgaaat tttttgcaat aatctccatg cccctttttt atatttatac
     9481 tacttgctcc aacttcatta aaattagaag ttccatttaa actaatatta acttcttcac
     9541 aattcaaaaa tccattacac tccaagattc cacttaaatt gatattttca caatctatat
     9601 tctcatttgc ttttaaatat ccttctccat gaataatatc cgattttata cttccttcta
     9661 cattaataat tccactagta tcaatttcaa cagaattaat atttcctgta catctaagaa
     9721 gtcccgatat ctcaactttt gatgccagta tgtttccttc tactttactt aaaccagatg
     9781 taaaaaattc attacattct gttgtcccaa aaacttttgc tgaaccagaa gaatcaaatt
     9841 tactacattt tacacttcct tctattttgc ctgttcctga tatattaaca ttatcaaaaa
     9901 ttccaccttt acattttcca acaccatcaa atcttagtga acttaattct tcattcataa
     9961 tgatatcctt tctttaccgt attttatctt taaacctaat ataacaaaac attgttacgt
    10021 tgtcaagtct gataataata cttaataaag caactatcat ttattttcta taaataggca
    10081 taaaaataat agggaaatgc tttatttaaa ctagaaatct aatttcttag attgtggttt
    10141 aaataaaata tatccctatt actcaatctt tatatattca ttgtataaac ttctaaaata
    10201 taagtcttta aattctactg tcaatacttt ttatacactg tttgtgctat catttcacac
    10261 ctaaaggagt aggctctccg cactattctg taacctaaaa gacactatct tcttctatct
    10321 attgataaat ttttctatta catcagctag tctctccata tcagttggat aaacttcacc
    10381 tatgctacct attctaaatg tatctatatc agtcaattta cctggataga taacaaatcc
    10441 attatctttt aaataagtat aaaattccat aaattcaaac tttgcatttt taggatataa
    10501 gaaagttgtt attacaggtg attgagcatt atcattcacc aaagtatcaa atcctaaaga
    10561 ttttaatctt gaagctattg taaactgatt ttctttatat ctagcatatc ttttttcaac
    10621 agaaccttct tcttccaatt ctaataaagc ttgataaaaa gctcttacaa catgtgtagg
    10681 tgaagtaaat ctccatttac cattattttt ctccatagtc tcccattgcg catacacatc
    10741 aagagataat gatttagcta tacctttaca tttagataat ttctctttat tagctattat
    10801 aaaaccaaat ccaggtactc cttgtataca tttgttagaa ctactaacta aaaaatctat
    10861 attaaaatct tcaacatcaa tctcaattcc cccaaaacta ctcatagcat caactatata
    10921 aattttgtta tattcttttg caagtttccc tacctcttgt ataggattta atctacctgt
    10981 agtagtttca cagtgaacca ttgatatatg tgttatatcc ttgttttctt ttaataaatt
    11041 ttctactaca tttaaatcca ctgcttctat atctttaaat gtgcagtcaa caaattctat
    11101 gttaagataa ttacatatat ctttcattct ctttccatat gctccatttg caattacaag
    11161 aagtttacca tcttttgaaa tagtacttcc tattatagct tctactgaaa aagtcccact
    11221 tccttgcatt aatacacttg tgtatttatc tgtattttgg gttgctagag atactaatct
    11281 tcttctaaca tcttgtacta ggttattata ttcaacatcc caagtacacc aatcttttaa
    11341 catagatgct cttactgatt tagtagtaga tagtggtcct ggtgtaagta atatgtaatc
    11401 attttctggt acaaaatctg atttaatagt ttcattctct atttttatta gtatatcttc
    11461 taactcagcc atagtttcta ttacaaaatg tgcacctgcc tctttaaatt tctttgaaac
    11521 tatactcatc ttagctttta attcttcctt atccatgttc tctacttctt cttgtgtaag
    11581 ccctaactca cttgaacctt ttattacagc aacactccac attcctgcat ttacgccttc
    11641 ttttacatca cttattgtat ctcctacttt taccatagaa ctcataggag acacccctaa
    11701 agcttcagca tttttatagc acatccaagg atacggtctt ccttgagata cttctgatgg
    11761 tgttacaaga aaatcgggtg agtatccttt ctttgctgca tttggttcaa ctatgttcat
    11821 catctctctt gtataacccg ttgtagaacc tatttttaat ccattttttc tcaacttttc
    11881 aatagtttca acaacatgag gaattggagt cgtatactct tctaatgtct caaataacat
    11941 tggctcaaat tcagcataaa gttcatttac atcatcttca gttggcactt taccaaactt
    12001 atctgaccaa agatttttta ttctatccat ttcacacatt tctcttatat ggtctatttt
    12061 taattttccc ataggttttc ttgcttcttc cattgttaca tctatacctc ttcttttaaa
    12121 tatctctata aatacattaa gaggtgcaaa acatccataa tctactgttg ttccagccca
    12181 atcgaatact actgctttta ttttttctcc atatatcttt ttcatattta tagcctccat
    12241 agattcattt tagaattttt gtgtttttaa ttgtttttac ttttaaagta taactttcat
    12301 atgttaatta tacatcatat ttaggttaaa tatatattaa atttctgttt ttagttgtat
    12361 ttaattgttt ttattttata tcatatttcc ataaaatcct aagttacaat ctaaaattta
    12421 ctttctaatc ttaatctatg aactgactat attttatgaa tttagttgta ttaagcatag
    12481 ttgtattata taaaactaag ggtttatttt gcttctatcc atgttatatt tatctcattt
    12541 aacttatcct tccattcatt cggaggttct acatcacaaa taacaaaatc taattcctct
    12601 aaatctgcta tcttatacat actagcaatt cctattttag aactatcaca taatacaaaa
    12661 ctttcctttg aattttttat atattctttt gacaacaatg ccttattttg gtctatacta
    12721 ctaattccaa aactatcaag tataccttca ctagatataa aagctttatc tacgtataag
    12781 tttttcatag tgtctattga cattggacat gctgtccttt ggtgttttaa atttactttt
    12841 ccaccaataa atataacttc tccatcaaac aaaccttgat tctcataaga aatcaatttt
    12901 gatagaactg gataagagtt tgtaataatt tttaaattgt ttacagatat tatataatct
    12961 acaatctgca aattggtagt accttcatct atgataattg actcattgtc atttacaaac
    13021 ttagctgcgt atttagcaat actttgtttt ttatctaggt tagtattgtt tctctttata
    13081 tgttctggtt caatcactcc ataatttatt tttatagcac caccatatac cttttttaat
    13141 ttattttcat tttctaattc ttccaaatat cttcttattg tttctgatga tacttctaat
    13201 ctttttacta attctttagt atttaccttc ccttttgaat ctaataattt aagtatttct
    13261 ttttttctat ctatcgaatt taaagacatt cattttcctc ctaaatataa tatatttttc
    13321 tcctataata ttacaatgat acctaagatt tatgaaatca tatttatgta ttaaattttt
    13381 tacttaatta aagttatttt caaaagactt tgtattatca ttaaaaaagt ccatcaaata
    13441 ttagtatcag atggactttg taaaatttta ttttataaat taatatttaa agtctaacta
    13501 ctaatttatt ttcttgtctc caagaatttt actaaattat ttacagtaga catatctttt
    13561 ctctctaaat cagttggttg aagctctatc cctaatctat tttcaatttc aagtaaaact
    13621 tcaattatag ctaatgagtc taaaagttcc gtctcaaata aattaaggtc taaatcttct
    13681 cttatctcat cagtccctaa tacatcttca aatatttcta taactgtttc ttgcataaat
    13741 tttcctcctt aaaattaagc taaataacct gagaatatca gcaatccaaa acacacaata
    13801 tggaatgtaa tgaaaatctg cactctctcg aaccatttat cttttttatg ttttttataa
    13861 aatttagatt ttcgctgata tatatcagtt aacacaagtg ccaatccttg gtatacacca
    13921 taagcaacat aataccaagt tagaccatgc caaaatccca ttgttatcat ggttatcatc
    13981 tgagccacat gagcagcagt agtccttttc ttaaatcttt tctttctcat tgatgacata
    14041 acaaatctag aaaaaatata atctccaaac catcttgaaa gacttatatg ccatcttgtc
    14101 cagaactctt tcatatcttt actgataaat ggcttgtcaa agtttatagg tacttgtatt
    14161 ccaaatatgt accctgtacc tatagcaaat aaactatatc ctgcaaaatc aaagaacagg
    14221 tataaactat atgcgtacat ataacttaaa atatttataa aactcatatc tttaggtatt
    14281 cttgataccc aatatgtatt tatcaaaaat gctataacaa acttataacc tactcccatg
    14341 acaatatttt ttattcctgg cagtaagtat tcttctatat actcttttct agagatgtgt
    14401 ttttccaagt cctgttcaaa tcttcttgac ctatcaatag gtccagaact taaagttgga
    14461 aaaaataaca taaaataaag catctttgaa attttaactt cttttatagc tccatcataa
    14521 atttcaataa ccatttgtat agttctgaaa tttaagtatg atattccaat aaatccaatt
    14581 attccaaaag aagtaactgg agatatttta tttattatta ttgggagcat tgatgcaaac
    14641 aagaatcccc aatatatgta tttattttta gtttttcttc ttacatattc atatccttta
    14701 actattatta cttcaagaat aataaatatt accaaatact ttagctggac atcaattcct
    14761 actattaaga atatcataaa caaacttgcc aacataccat aatactttat attcttgccc
    14821 attagaccta aaattactgc tggtattgat gttaataata atatataaag ataaaaataa
    14881 tctccatact gtgaaaaaat cattaaattt cctccataag tttctttctg tctattttac
    14941 cattgatatt tgttggaaac tcagagatta ttgaaatatt tcttggaatc atatatgaag
    15001 gtatatactt tccaagttcc ttttttatta tcatcccatt tttaatatta cttaaatcat
    15061 tcttttcatt taactcaaca atacctttta agtaagcaat tttttcgtcc ttatatactg
    15121 gtaaaactac tgcatttttt acattatgta cttttctcaa attattttct atatcttcta
    15181 tttcaattct aaatccattt aatttaatct gaaaatcttt tcttccacaa taatatatat
    15241 ttccatctaa aagatatccc atatctccag ttttataagc tctccacttt acaccatcta
    15301 tttcatcata gaaaaatact tcatcagtct tttctttatt attgaagtaa cctttagaaa
    15361 ctgatggtcc aattattata atttcaccct tttcattttc tttaagttca tttccatctt
    15421 catcaagtat ttttatttta caatttgaca tagggtatcc aactggaaga cttttttcat
    15481 catctatagc tttttgagtc atatcattta cacttacacc aacagtagcc tcggttggtc
    15541 catatccatt gataattctt gtgtttggaa atctactcat aagttcttta gtaagatttt
    15601 ttgaaagtgc ttctcctatg aatatcattg actcaaggtt aggaagcatt ttactattaa
    15661 actctttttc agttatacat actcctgcaa aagaaggagt tgacacccat acagctatat
    15721 ctgagatact aaattgtcta aatagttctt tatagtctgc taatacatct tttgatattg
    15781 aaaataatgt agctccatgg ataagaccag ggtatattgt tgtaactgaa aggtcaaaag
    15841 aatatgctgg ttggttcatt attacttttt cacttccatc tatgtttaga tatgggctta
    15901 tccaatctga aaagctatct aaattgtttg aacttatttg aacccctttt ggctttcctg
    15961 tacttcctga agtaaatagt atatatgcat tttcatcatc ttttacccag ttttctttat
    16021 ctaatgattt tccctgatat tcatttatta tatcatttaa tttatccata tcaattacat
    16081 tgatatctcc aaaatttctt tcatcactaa aattaaatat tacttttggt tttatctctt
    16141 tagtgacttc aaaaactcta tcaattggaa aactaatatc aagaggcaca tacgctctac
    16201 ctgattttaa agctcctatc atacatgcca ttatcatgtt ttctttattt ccataaatta
    16261 ctataggagt atcctcttct ttgtatacat cctttagaaa tactgatata gcatctgaat
    16321 attcatttaa atctttataa gaaagtttat ctccattaca cattagtgct gttctatctg
    16381 tatttgaata tttttttatt ccttcaataa ttttcatata agaatgctcc tttaaaatcc
    16441 gttataaata aatggcaatt ctttaaatgg agtaaatgtt agaactccta tcgccaatat
    16501 tataaccata gttaaacaaa tactagttaa caaatcttta ttgttcttta aatattttaa
    16561 ataatctctc acagacatct acccatcctt tcgtaccaag atgcattaca tcccttaaat
    16621 aatacttatc tgacccttta tctttaaggt ttagaacttc aaagcctttg ctttctgcta
    16681 ttttttgtgc tttatcgtag tactgatttc tttctttttc agaaatacca gtcaaattat
    16741 agaatttatc catacttggg attaatacaa caactggatt aatacctaag tcagtacata
    16801 catttagcat cagtttataa ttttcaaact ccttagatgt taataaattt acatctttgt
    16861 ctcttccttt gtattgctct ataccatctt taaaatgctc tttataatag tacttatcaa
    16921 tatttagtgg atttttacca actctttttt tagcatcttc aatggctttc tttctctcat
    16981 atgaccaatt tattggtctt tttctttttg ttgctctctt tttatctagc ttaattaatc
    17041 gtttataaag aatacccttt tctttaagag ctatacagta ctttcttcct tgaaaataag
    17101 gctctaaaag caccttttca gctttttcag gaaatgtctt aggttcatat agcttagcat
    17161 ataatgcttc tgctttatac tcatcacttc cccataatag cttacttgat ttttttgcat
    17221 attcaatctt attttgttta gatatttttg gattatctaa aaatcgataa aattgtattg
    17281 gtgaaaatct agactgataa tggtgacttg tgactccgtc tttttccata aaccattgca
    17341 tagaaattaa caagacaact ttcttattat caatattagg attcatactt cctaatattg
    17401 cagcatcttg taatgtctga gtataggctc tcccaattgc aaacacctta tttttactcc
    17461 tatttgtatt aaaatagtac tttggatgtt gttttgttga attactaagt tctgatgacc
    17521 ccaaaatcat aatatccttt tctcttaaaa aatgattatt tgctgtaacc cctttatctt
    17581 ttatatcact taaagtatca tccataattg gaagtagatt tttctccctc aaaagttcat
    17641 cagttttaga atcaagaaat ttgtctaacc caaataaaaa tactacgcct attataaaag
    17701 gtgtaataaa gtatatcaat tttctcatat tttctctcct ctaaaaatat tcaaatttat
    17761 gttattatta atcatattag ttttgatatg tatattcaac tacaaaattg taataaaatc
    17821 gtcaaaactt tttttgatac tgttacaaaa ttgtaaaaaa aaaagaaaaa aacaccaaaa
    17881 ataaatttct ttttagcact ttttcatact tataatttga cattttaaca cttggctaag
    17941 tatacacctt accttaactt aaaattaaat ttatttaaga atatatatta taaattctta
    18001 tattttctaa tataagctat atactatcag ctggataaac aatactactt tgtcttctta
    18061 tctcatccat aatttccatt actattattg aattttcatg agaatttata tttgattcta
    18121 ttttattgtt atttataaga cttataaact ctacaagttc ataatacatt ccttctattt
    18181 ctctaggctt ttcctctgct ttttcttttg gaatagatat atcttcttct cttccatctc
    18241 tgtatttaat aatagctttt tcaaatagat taagcttttc aattattata cttccctctt
    18301 ctccttgtat ttcagatggt atataagaat cagctacttt agaatactga attattgcat
    18361 ccatatcatc atattgaaat acagctgaac cttctccatc cactccagtt tgaagtatat
    18421 gagaaactgc ctttacagtt tttggagcac caaataaatt caccatagga tgtatacaat
    18481 acactcctat atccattaaa gctccatttg acaactcttt tttaaaggca ttttctataa
    18541 ttccattttt atatttatca tatcttgaag aatactgaca atagcttcca aaaaatcttc
    18601 ttattttccc tattttatac aagttttctt taactgcttt aaagtttgga acacatgtaa
    18661 ttctcatagc ttccataagc aatacattat tatctttggc tgtttttatc attgatttga
    18721 cttcttttaa attagatgct aacgactttt cacaaagcac atgttttttg tgttttaaac
    18781 aagtaatggc ttgctttgaa tgtaatgcat ttggagaagc tatatataca gcatctatat
    18841 ccttcgattt agccatttgt tctaaatcat caaaaaaaat acttgctcca tgtagagttc
    18901 caaattctct agctttttct aaatttctag aatatacagc aaccaattca aaatctttaa
    18961 ccctagatgc agctcttaga aatatatttg ctatattgct tgtcccaaca ataccaaatc
    19021 ttattttacc catcataaat cactccccat tttctacact ttattttaat tttaataaaa
    19081 aactttacaa cttatagata tattataaaa taattttatc aaataaaaaa gaaagctaat
    19141 tttaaatgat ttcaccattt taacatagct ttcttttaac tacaatctaa attcaactta
    19201 tatttttaaa gttatctttc tactatatct ttatttcccc tcaaaaattt tatagtaaga
    19261 atttcatcca caaacaatgt tactaaaagt atagttacaa gaattggcca ataaggtatt
    19321 ataagactat ataaactatc aactatatac acttgaaaat atctaactcc aataaatgtc
    19381 aatatagtcc aatatacaga aaactttaga catactattc ctctactatt gtacttataa
    19441 tctgaataat cccaatagac cttattaaaa tatactttca taagtattcc tgtaatatat
    19501 tctactactg tcggcactac tagacataat aaaagcaatg caaatatatt attggggtca
    19561 ataaatcttg agacctctat tataatcgac attgcaattg catacattgg tttaaatgga
    19621 ccatttaaaa atccatcttc ttgaaaatgc ccttgtttat aataactata taagttttca
    19681 attatccaac ctataaaacc atacaagaaa aaattaaata aaaaatataa tagagaacct
    19741 acattatcca tgaatattcc tcctagctgt ttatacttat tttttctcat attcatggat
    19801 ttattctaaa tcaaagaaat tatatttaat ttatttaatt aatactttat attatagatt
    19861 gtgacattct ttagagttca aactttttag gtattctcta acttccagta aattttcaag
    19921 tatcttatgt gattgtgatt taatttgctc atctggctct tttaaatctg gtacatttat
    19981 acatcttatc ccaccattgt atgcagcttc aactcccata ggcgaatcct ctatgacaat
    20041 acaattttgg ggattaacat ttatcttttt agctgctttt aagaatatct cagggtttgg
    20101 tttagagttt acaacatcat ctccacaaac tatagcatca aagtaatctt ttaaatttgc
    20161 cttagctaat ctctttactg ctctttctct ctttgttgat gttgcaacag ccattttgta
    20221 tccattttcc tttaaaaaag agattagttc attgactcct aatttgatag gagctccctt
    20281 cctctccata aattcaatca tatttttagt tttttcgtca tataaatcta ttattggtac
    20341 agaactatcg tatatatctg taagaccttc tattattcct ttacgatttc ttcccataac
    20401 tgatgtataa atttccttag tcatagtata tccatacttt tcaaacgtct ccatccaaaa
    20461 ttcaagagaa attctctctg agtcaaacaa aactccatcc atgtcaaaaa taattccttc
    20521 tactttttgc atacaattcc tccaatattt tttgatataa ttatattaca ctttttatga
    20581 ttaattttac aaccctcaat ttatccaatt ctaatattgt aaaattgtaa ttttcaaaag
    20641 ttacgctttg gtttacttta atatttgaac caagcatata ggatatccac ccacctatac
    20701 tgtcaaatcc atcatgctct atatcaagtc caaaatactt attaatatag ttgatagatt
    20761 cagttccatc aactaagtaa gaacctgctc ctattttctt aatatgagtc tcttctttgt
    20821 caaattcatc ttgaatttct ccaactatct cttctagtat atcttctatt gttaccacac
    20881 cagatgtacc accatattca tccacaacta tagcaagttg aagtttttcc tttcttattc
    20941 tctcaagagc tttatctata gttaaatttt cagatatata tataatatct ctcaatattt
    21001 cttctagttc aattttattt tcatttatct tttgattgta taaatctctt atatgtacaa
    21061 aacctaatat atcatcttta ttttttctgc atactggata tcttgtaaca ccttcctctt
    21121 ttaaaatagc taatatcttt tcttcagaat cactttcata tatacatacc atatcagttc
    21181 taggaaccat tatctctcta attttctttt cttcaaattc aaaaatatta tcaactaatc
    21241 tttgctctga ttcatctata agtccacttt tataactttc ttctactaat agtcttattt
    21301 cgtcacctgt atggggttca tcaacctcat cagcttgtga atatccaaat ggtttaagaa
    21361 ataaatcagt acttaagttg aaaaaatata ttattggata tgttaactta taaaatccta
    21421 ctaataaaaa agatgtactc aacattattt tttctgtatt ataaagtgct aaagctttag
    21481 gaaccaactc tcctattaca acctccatca ttgttataat taaaaaagaa atggaaattg
    21541 atatagtata tataatactt tcactaagat taaatacact tactattggt aaaattaact
    21601 ctttaactgt agattctccc atccaaccta atgcaagtga acaaagtgtt ataccaagtt
    21661 gacatgcaga aagataggaa tttaagttgt cttttattat tttacatctt tttgcattat
    21721 tattaccttc agttatcatg gtatcaatcc tagaactacg aagttttacc atagcaaatt
    21781 cacaagctac aaaaaaagca tttatcaaaa caagcattac tataagtgtt acttttaata
    21841 actcccgcat aaagtattgg ttcttataat gtaagaaatc tataagaact caaagttccc
    21901 cccttatatt tataaattta atttataata tatattctat catatttatt aatatatcct
    21961 actttattac aaataatttt tataaactaa ataacccctt taatatttat gactgtctat
    22021 ttgataaata ttaaaggggt tatttagtta tcatttttta tttctaaaaa tcttttctca
    22081 aatgatttag ttatctattt atccaatttt ttacataatt taatgattaa aaatattaat
    22141 tttttcacta taaagtataa atattttttg tataaatatt atctgattat taaaataaat
    22201 attaatacta taaataaaaa cgaagcatga tttttattta aataaatccc aaacttcgtc
    22261 tttacttact tagatattta tttactttct aaatcctatt atttttaaaa ccttatcttt
    22321 ttaatacttc accacattta ttctcagtaa tctctccatt ttctaacgca atttttccat
    22381 ttacaattac atattcaaca ccattggcta gtaattgtgg ctttgaaaaa tcaatatctt
    22441 ctgacctaga ataactatag ttatccatgt caataactgc tatatcagct atcaaccctt
    22501 ctttaataat acctctattt tttattttaa attgcctagc tggtaatgaa gtaactcttc
    22561 ttacaatctc ttccaatcta acaccagact ttctgtacat attgaagaaa attggaaaag
    22621 ctcctcttct ttgtagttca aaccatgaca tatccccacc cacactaaac aaacaatctg
    22681 aaccaaccat aacaaatgga ttatcaatta ttttattatc atgtagttta tctgggaaat
    22741 cagctctata cattcctcct aaacaaaaga taagttcttc gtctccatct aaaagtaaat
    22801 cgagtaataa cttgtcctca tctattcctt tttgtgtagc tatttcacgt attgatttct
    22861 tttccatatt aatatcttta gtgtttagaa gtattatact ccccctatct ccaagtataa
    22921 atgcttcttt taatataagt gttcttccct cttcatttct aagatcatcc attaccccat
    22981 ctatacctaa ttcaaataga ctagatgata ttgccataat aaattgaatt actctttttt
    23041 tcttcataca atgcccagaa cttcttggta ctgtgtcaac cattatttca acaccattat
    23101 acctagcctt taatatctca tcaaatgctt ctatttcaac tggacttaag tgagatactt
    23161 gaaccctagc accacttttt tgcccaacct ctatggcttc ttttactgca ttatatcttc
    23221 ctatgtaatc tctaatatga gatgtatata taccatcatg ctctttaatc tgccttgcaa
    23281 tatcaacaag ttcatcaata tcagcatact tacttggtat atatgccaat ccagtagata
    23341 ttccaaaagc accacttttc attccatcat ttattatatc tgtaatttca tttttttcct
    23401 tttctgtagg aggtctatcc ttagaacctc ccataacact ccatcttata gtcccatgcc
    23461 ccaacaagaa tcccatattg acagaaatac cacttttaga tataaggtca caatattctg
    23521 taaaattatt ccaacattta tttttatcta taagatactt tttttcttct tcaagtaata
    23581 gaccattttt atacatatat tcatatacat tttcagaaga atatggtgtt atagaatgtc
    23641 cacaattacc atttatagtt gttgtaactc cttgttttag aaacttttca aatttaccat
    23701 ctagtattgc tactatttct tcatgaacat gagggtcaat aaatccaggt gttataactt
    23761 ttccacaaca atcaatctct ttatttgtat tgctatttat cttagaatct atttttgcta
    23821 ttaagttgtc tttaattgct atatctccat aaaaaccagg attacctgta ccatctatta
    23881 taaatccatt ttttaagatt aaatcatata tcaaaatatt ccctccttaa aaaccaattt
    23941 ttaaataatc ttaatgtaat ttttatattt gaaaatcaaa ttattatatt tcatatttga
    24001 aaattcacta ttatttcatt gtaattagtc actaagctta tctttataca tagctcttgc
    24061 aattaatata gtaccaaata cacatataag aactactaga gactgtggta ttataccttg
    24121 ctttgataat ataatagtca atacagatat tacaattgct actagaccta attttttatc
    24181 ttgtaaaaat acttgtccaa aaactgaccc aaatagagct ggtaaaatta agtttaattt
    24241 ttctactact tcagctggaa ttttagataa tacgcttcct cctaaaatta cccctatagt
    24301 tagtatactt atattcacta aaatagatac agctattcct attgtagata ttatcgagcc
    24361 ttcttctgta cctgattcaa cttctgctgc cttttgagct gctattgaac atggtagcct
    24421 catattagat atattaccag aaagaaaact catataagtt cctgggatac ctaagattgg
    24481 tgaataagaa actggttcta ttatgtaatt tggagcactc atactgacaa ttgccattgt
    24541 acttgctaat aatgctgata ttggaggcat aataccaaat ccaaagctca aaattattcc
    24601 aggaactaat gctgctataa tacctaaaga tagtgttagt cttccatacc ttatcataaa
    24661 aggtaaatat tcttcattgt atatagattt tactttactc ataaaactcc ccccttatat
    24721 tactgaagct attatcattc cgctaaacat tgatattgta agcccccact ctcttaacca
    24781 ttttatattt ttcttctttt caagcataca caatattacc attatagcca ttccacttat
    24841 acatgcaatt gttccattat caaaacgcaa caccctatca gcatttagat atgcaaatga
    24901 acccaacatt gctcctagag atattattgg tataaatgat ttcttgccac tagatataac
    24961 attggttatc ttatctagtt tatgtccaaa tagtaatgtg aatattatcc atcctaaaga
    25021 acctaatatc atagtccaaa ctgcatttgt aaatgcaagt tttgtcattt caggagaacc
    25081 taaagttata cctaatgcat ctgttccaaa tccagctgac attgattcaa aaattacaga
    25141 acctataaat gataatctca tccatgctat aggcccaccc atagttacta taagcgatac
    25201 cattccagca aatatagtca ttgaaggccc aatagctgaa atagcactac tcttaacagc
    25261 tgactttatt tgtttatctg ttattcccat tgttttacca actttgcaag attttatagc
    25321 aaatataagg gattgtacca ctactattga tactgctact gtactcgcta tccacaaaag
    25381 tggatgatta gctaatttta aataatccat ttataaaacc tccctataaa tcctcaaatt
    25441 ttattaatat ttctaatata tctatttcca aacctgtttt agtactctaa gtatatttcc
    25501 acctagtacc ttctctattt cctcatcact atatccatgc tttactaaat atctgacaat
    25561 gttttttgaa gtttctgttg ggttctcaag accttttaca tattctactt tgggatgttc
    25621 ttttgtacct gttatttttt ttatatcaaa tttagcagct agtactgagt gtaattttac
    25681 atggtcgcca tatactgtat ctggtccaaa agctacatgg tctattccta ctaaattttt
    25741 aatatactca aaatgttcca taaatgactc tattgaatgt tctttattct tctctgttat
    25801 tgtagtatga ggtgctgctt ctacacctat aacccctcct tttttagcac atgctattaa
    25861 tacttcatct ggagttagtc tctttgtgtt ccataaattt cttgccccaa catggcttaa
    25921 tattattggg tccttgctat attctattac atcaagtgta gtttgaactc caacgtgaga
    25981 gcaatctatt gccattccaa ttttattcat tctttcaaca gctttttttc cgaaatttgt
    26041 aagacctcca tctttctctt cttttagtcc tgaacctaat gcattggatt cgctgtatgt
    26101 tatacccatt aaccttatac caaatccata cagtatatct attctatcaa gttcattttc
    26161 tattggtgct gcaccttcta atgttggtat caatgctact ttaccttcac ttttagctct
    26221 gcatatatct tctacttttt cacactttat gacaaaatct tgatgagcta aatcacatag
    26281 tctcatgcct aaatctatta atatatcatc ccatttccac cctgaatttg atgttatcgt
    26341 acatacacca tccattaaat tatcaaatat agcatcataa tatcctcttg ataatgcttc
    26401 ataagcgcat ctttgtttac cttccctatt atattcaaat atatctcttt ctaggtgttc
    26461 tggaaataat actggatgtt catgtaatga tataaatatt ttttcatcca ctatactttt
    26521 aaccttagct tcttgaatat catctaattc aataaggtac tctttaactc ttttatctcc
    26581 tttacacatc tcaatagatg aaatatcttt tcctttttct aaataactat aggcttcata
    26641 tcctttgtaa gctgacttca taacaacatc ctccaagttc tacaattttt tatatttttc
    26701 ctatgtagca attgatatgc caaaatataa attttaattg tataataaat cttgcaaaaa
    26761 ataaaaacag tagtaaggtt gatatttact actgttttat taaaaataat cttcttagat
    26821 tatttattca atatttttga attatcttaa tcttaaagat aattttattt atttctatcc
    26881 attataggga tttttttagg gtgttttgcc tttttagtcc cctatatcac tcccttaatt
    26941 tttacatatg atataaagtt ctttccttca tcagttataa aactaccttg tttttttact
    27001 ccagataaaa gtaaaccatg gctctttaac ttatctattc tttttctaat ttggtctaca
    27061 cttaaaacta tatctttttc ttttaaaatc tcttgcagtt tatttcttcc taataatata
    27121 tttttattat tccaagtttc tatactgttc aatatacata tactttcctc aaagaaatta
    27181 gattgtttga aatctaagat aattgaatcg aaattttcat taactaaagt attgtttttt
    27241 tcaaatctaa attgttctgg caaatgctcg taatctactc tatcttcctc aactatagta
    27301 tcaatataat aaattaaatt tttaagctct cttacatttc ctggccattc atacaatgtt
    27361 aaagcttgca ttgattcctc tgtaaaacat ttgttgctat ttatttcatc taaaaaatac
    27421 ttacttataa gaggtatatc ttccttacgt tctctaagtc taggtatctc tatatgtaat
    27481 acattaatcc tataatacaa atcttctcta aaagaacctt ctttaatttt tttctttaaa
    27541 tctttatttg ttgcagctat aattctaaca tctattggta taattttact tccgcccatt
    27601 ctcataactt ctttttcctg taatactctt agcaatctct gctgtacatc taaagatata
    27661 tcacctatct catctaaaaa aattgttcct gtatgcgctc tttcaaatat acccattttt
    27721 ccacctttta ttgctcctgt aaaacttcct tcatcatagc caaaaagttc actttcaata
    27781 agtgtatctg acaaagaaga tagattaact gcaacaaatg gcttgttttt tcttagagat
    27841 tcattatgta ttgcctgggc aaatatttct tttcctgttc cattttctcc aagtatcaac
    27901 acagaaaagt ctgtagttgc tatttttctt gcaatattaa ttttttcttt tattatttta
    27961 ctctcaccta caacactctc aaatgtatac tttgatacaa aaccttttga ctgaagttta
    28021 ttttgaatct tgtcctcaag cacttgaatt gcacttatat ttttaatgct tataatactc
    28081 tttattcgtt cattattttc ataaacattt actttattaa ttatcagttt tttgttattt
    28141 aaatttacta cttcatcatt aacttcatct tcttgaaaaa atattttttt gacaacctta
    28201 tcactaaata agtccataaa gttattagat ataatttcat tttggtctat tccaactaga
    28261 ttagaaaata ctttgttgca atatataaat tttcctaatt tatcaacaga ggcaatacct
    28321 tcatctataa tctccaaaaa actcttcatg gttttattca tagttgtata atacctatat
    28381 ccacttactg tatcttcatt gtatttttcc ttaataatat gtaatttatc tatagatata
    28441 tttagttttg taaagatttc tataactgta tttatatcaa ttaccttatc acctatgtca
    28501 attatttgct ttatgttttg tggtatgctg tttctgcttc ccgtaataat tccaatctca
    28561 catttagact tatcacaacc tggataatat ggtattagat taatatgaat taatcctagt
    28621 tttctaatta tcttggcagt ttcatctgct gactctttat aagcatctat aaccataaca
    28681 tcagaatcat tttctatact tattatctga tttatatttt caatatttat agtacgatgt
    28741 actattacaa taagtatatt tttatcaata ttattatgta tatattcctt tatatcattg
    28801 tctgaacata ctacaagctc atagcttgac agttcaatat ttatcctatt tacatatacc
    28861 aagttatcta tattacaaaa ttctccaaat atattttcca attgttttga tatatctata
    28921 tttattttgt catcagttga tacaaataaa atattatgtt ttttcatagt cccacctcct
    28981 gtttaacgag tatagaaagt aataatttgg tctattgtag cactttttaa aaaagtttta
    29041 aatcttaaaa atcaaatttt gtaccattta ctattatttt ccataataaa ataatgtaag
    29101 ctatcttttt tcacatataa tttaatttct aaaacggtta gtttgacatt attggaatat
    29161 aaacaaaaat ttaatataaa ttcgttaata tattaataca tttttaagaa tgacaaggaa
    29221 taaattataa caaattttag gaatatataa taatagggtc tcagaactta gttacaagtt
    29281 ctaaaaccct atttgtttag tgtaaaaaac atcataaaat ttagcttaaa tcttttcaca
    29341 taatattact ctttttctaa gtgataataa aatatatcta ttcctctaaa aactgtaaaa
    29401 attcctgatt aaatagttta agctcatcat agaatatagc atgaccacta tactcaaaag
    29461 tatataaaat tgaatcttct attttttcat tcataaaaac tgcaaattca tacggacata
    29521 tttcatctaa tttcccatga aatataccag taggcactct tacacatttt aaatcattaa
    29581 ataattcttc atctcttaaa gatacagcag ttccaatagt gccaatacct gatgcactaa
    29641 aaccaatatc attaaaccat cttctaaagc tttctggtgg atttgatgca aatacttttt
    29701 ctccaaaatc ggttaccatt tctggtctat cagtacatgc ttgtgctatc aatttattta
    29761 catcttcacg tgtcatacca tatggaaatt ctggaggtct ttgtacaaat gatggtgcag
    29821 cagctgcagc taataccaat tttgacactc catatccatt aaataaactc atatacctaa
    29881 gtacgattgc tcctcccatt gaaaaaccaa caaaggtaaa gtcttttaat ccaatagcat
    29941 gtaccacctt ataaatatcg tctgctaatt ggctataagt atatcctcct gatgttgcat
    30001 cagatttacc aaaacctctt aaatcaattg aaactgttct atatccgagt tttggcaata
    30061 tatttgtttg atattcaaat atcttatgtc ctaagggcca accatgtata aaaagtacag
    30121 tttttttagc actcggattc aaatcatata ctgctatgtt tatatcattc acatatacat
    30181 aatacatatc aacagcaact cccttcaaga aaatgtatga tggttatttt atatatatga
    30241 ataaaatgat gaataactaa atttttaaat ttatttacaa tacttctcta ttgccttttc
    30301 aaataaactt acatgaagtt tttcatctag gattattcta tttaatatag cttttatata
    30361 agggtcttca ataagactta tatctttata ataattatta atagccacat gctccaaatg
    30421 caaatctagt tttaatctgt tacaaataga atttccataa catacaaaac caccattcca
    30481 atatgcacca caagaacttg tagaacctct atatacagga tttccaccca ataatcttat
    30541 agtctttgct aatatctcca tatgtaacat ttctgttata gatatattta tccacatttc
    30601 acttaactct ctatgcgttt catctaaatc aaaattatgg tatagatatt gatttacact
    30661 cgtaaattca cttgatactc cggcatagtc atccatcaat aattctgcat aatacttatt
    30721 tagacctaaa acttttatct ctggatatgg ctcatcactt gaatatccat ttcgcttgtg
    30781 catgtcgtaa tgtgcatcac tcataatatc tcctccttta aatttaatac ttgatattaa
    30841 ttgtatgcat cacgactttt tcatataact tagataataa aatctattat attattttct
    30901 attataattt atgtgtcaat tcacccaaat ttatttgata tgcaatattt ctttccttag
    30961 tgctacatat gtaataaaaa catatataca atatattact acaaaattaa taagcgtaat
    31021 ggctacagca tgtaagatag gaatctgaat attaaaaaat actggagcat caaaagaaat
    31081 attaaacatg ttgtatgaaa aaactgatac caatattcca ccaaatatta ctgcaggaat
    31141 taatggaatc gaaaaatata aacaaacatg tttctttaag atttttatta cttcactatc
    31201 aatcatcccc aaagttcgaa gcattccata gtgttttatg ataatgttat tttcgctcaa
    31261 taattgaata gagagaatga ctgtaccaat aatgcatata atgagtgcca aataaaaaag
    31321 tggtaatatc aagataatgg cttgaccagt agattgcata gcatactttc cacttatata
    31381 atccttatta tcatatcgta atttagaaac aaagccttga ttacctgcta ctactactcc
    31441 agaattaaga ttttctaaag tatcaaactt tttctgaaac tcagtaaaat aagcactatc
    31501 caaaggctca cttgtaatag caacataaag actatacaga ggtttcatat tatcaattaa
    31561 ataatctgga atgacaataa tatattcttg tccatttcca tatcctccat actgtgaaaa
    31621 gttctctata taaatacctg caatacttaa gtccttatct gatattgtca gtttatattt
    31681 ttctccaata taattcttat atgcatcagc aagataaggc atacaatgga tgataaattg
    31741 atttttgtcc atctttattg ggtttaaacc caacatattt cttagtatat tgtaatcact
    31801 atatttcata aatgtgtcaa actggttttc tgcaaaagta taatccttat attgtaaatc
    31861 tcgccctata tctttcaagt atttagaaag gatattatta cgaaccttca taaaggatgt
    31921 tttttcttct gtgtaaagag tataagaata atcctttttc acacctttcg tttctgataa
    31981 atatccttca tatgaagaaa aatcatatga ttcattcggg tgaaaaatac tcacatcaaa
    32041 ttgttgtaaa tccactgatt tattcatcac agaataaaat gagttagcta ttccaataca
    32101 agcaattgat actgtaaaaa gagttgcgat aatacccatt ataatgctta ttccatttat
    32161 ctttgaagcc agtagacgat acaaaaataa gtgagatttc ttatatttcc aattcatccc
    32221 tttttcaaac atattctgtg caatagatcc aaatcccata aataatacga ttagacaaaa
    32281 tacaatcaac aataaaccaa gaaatacatc tgttaatcta ccactaggta ttgaaaagaa
    32341 aaaaataccc atacctccac acaaaacaga cacacaaaac ataatagact tcgtttttgt
    32401 ttggtgaatt aatacatttt cattatatcg atcataatta agcaaattaa ttaatttcat
    32461 tttaacaagt tttttattac tttttaattg agcaattaaa tatattatgc agaagtataa
    32521 aaaagtcatc ccagcagctt ttaatgaaaa atccggagat aaagaatact ttccatgaaa
    32581 catattaata acaatagatt ccaaaacctt agaaacaaat atccctagaa tccatccaac
    32641 aataagagca gaagcaccta ataaaagatt ctctataaaa agcattttaa caatttgttt
    32701 tttatctact cctaatatca tataagtact tatttctctg cttctttttt tcaatataaa
    32761 attcatcata taactaacaa accagcctaa aataaaagta ataatgaacg aaaatatgat
    32821 aatcatataa gaaaactcat cgcttcctcc attattaagt atactagaaa gttcttgcat
    32881 tacgtcggaa aatatcaaag cgttaaaagc ataaatcaaa gctacagagc ctattaagga
    32941 acaccaataa ataaggtact ttcctgcttg tcgtcttgca ttacgaaaag ataatccttt
    33001 caacataatc aatctcctcc catcaaagaa agtgcatcca aaatttcgtg atagaaagta
    33061 agtctggatt tttctccttt tctaagttcg ttaaaaattt tcccatccct tagaaataaa
    33121 attctctcag tataactagc tgaaatagcg tcgtgtgtga caagaagaat cgtagcctct
    33181 aatatggtgt ttatagtttc caaaagttcc attaaagttt tagatgaatt agaatccaat
    33241 gcaccagttg gttcatctgc caaaataagt ttgggctctg ttacaactgc acgagctact
    33301 gcacaacgtt gcctctgacc accagatact tcataaggaa acttcgaaag tatctcttca
    33361 attttcaatt gtgtggcaat attatacaca ctattagtaa tttcaacagg agaaactttt
    33421 tttattgtaa gtggaagtgc tatattttct tctaatgtca gagtatctaa taaattagaa
    33481 tcctgaaaaa caaaacctaa attatcacga cgaaaaacag ttaagttttc ttcggatagt
    33541 tcagtaatat cttgattttc aagataaatt tttccagcac ttactgtatc aattgtagca
    33601 atacaattta acaaagtagt tttaccagag ccagaagttc ccataatact gacaaactct
    33661 cctgtattaa tttgaaatga cacatcattc aaggcctttg taagtatttt ctgattgcca
    33721 taatatttct caatgttctc tactcgtaat agcatgttaa agtcctcctt agtcaacaat
    33781 ttttccattt ttaattatta ttgtcttatc tgaaaaattc aagatatata catatatgct
    33841 ttctttagag tcttgaattt gaatagtagg ttcattagat gaaattagag atttttttac
    33901 ttcaatatcg tattttattg ttaattcatt atcatctcca tttttattag tatcttctac
    33961 atttttattt aaatcaatgt tattatgatt aaagggacca gtaaacttta cttctgtaat
    34021 agttccattt tttctaataa aagaagcata ttcagacctt agtggtatga tacttcgtga
    34081 gaaaaaaccc atcgaatcca atcctgtaat tgaaataaac aaaacgagta caacacataa
    34141 tatagttaat atcctttttt tcatatgttt ctccctcctt tctattgata ttgtagcgta
    34201 aatagtaatc tgaatatata gaagttactt aactttatct tacagttttg aaagataaag
    34261 aaatagcagc gcatttttag ttgcactgct tctgcatatt gatagctgta tttattggga
    34321 aattcaatgt tattgctgtg tattcaccaa ggctggagga cacatctata tcaattccca
    34381 ttttcttaga cagttcataa caaaggtaaa gaccaatccc tgtagaattg tttgtagtcc
    34441 ttccattact gccagtaaaa cctaattcaa aaattcgata aatttcactt tctttgatgc
    34501 caataccatt atcttttata gtaaacttaa cactcttgtc ttcttttatt gcaaaaaatg
    34561 aaatttcagc tgaatcactt ttgtactgaa cactattgat aataatttga tttaaaataa
    34621 aaactatcca ctttttatca gtatatacac tatactccaa atcctgtata ttaatatgaa
    34681 tattattttg tataagaagc aatttattct ttgctaatac ttcttctaca attgacttta
    34741 atgttatttc agaaattaaa taatcttttt caacatggcc aaggcgagca tagtacaatg
    34801 cacgctcaat atgacgttct atttcttcca tttgaaaacg aatttttcgt gtatgttcat
    34861 ttttataatt ttcacatata agttctgatg ttgtaacagg atgttttatc tcatgtaccc
    34921 attgttcaat gaattgtcta tattcgtaca tttcacgatg tatttgagaa acatgatctg
    34981 tcatagattt caatgataat ctaataatat tgtagtattc acgttctatg ttagaagtag
    35041 gtttttcaat catttcaata aacagatatt ttttatccaa ttcgtctaca atgcgacgta
    35101 acttaataat ttcttttttc tgtttttgat aacaaaaaca tatccaacaa aataaaattg
    35161 cgacccaagc ggctataaga agagtcaact ctccttgacc aatccctata agatgaagat
    35221 atagcactaa tgaaattgca caacaaatat ttaagagtat aactaatact ttatcttgaa
    35281 gaaaattaca aaacctcata tcctatatcc catcccccgt tttgtaatga ttaagtcagt
    35341 aatacctata ccccttaact tttctctaag ccttgtaatg tttacactta aagcattatc
    35401 atcaatatga atatgattgt cccataaata ttctaccaaa tctatacgag gcacaatact
    35461 ccctacattc tgaaacaaat aatacatgat ttttagttca gttcttgaaa gttctataac
    35521 agcattttgg tattctactg tagctgaaat aaggttgagt ataatctctc tatatttaat
    35581 tttctgttta tctgatgaat ctactctttt aagtaggttc tttacccttg ctaaaagcaa
    35641 aggtaagtta tatggttttg taatatagtc atctcccccc atagtcaaac catttagttc
    35701 atcaattgca ctatctcttg ctgtaataaa aataataggt atagtagaac aattcctaat
    35761 ctgtctacat aaagaaaaac catctatatt aggcaaattg atatccaaga gaattaagtc
    35821 aggtgttgat tcttggatta cttgaagtac atcacaatta tttgtatcca atgtttgtgt
    35881 actatagcca ttattttcaa agaattgcat taattcctta cagatgaaca catcatcttc
    35941 aattatcaaa atattggtta aaataataaa tacctcattt ctttagttta tattgcttta
    36001 attttgtaag taatatattt ttccatatat tacttacaaa attacttttt aattattcat
    36061 cttttccagc tactgatagc tctttaataa caactgaagg tgaacctata ctactcattg
    36121 gaaattctaa atcttcccct ataacttcaa tatctttcaa caggtcaaaa tagtttcctg
    36181 ctactgtaat ttgctccact ggaaatactt tttttccttc tttgatataa aagcctttgg
    36241 cagctaaaga aaagtctcct gttactgaat ttgcacctga atgaagccct gcaaagctag
    36301 taaccatcaa tccttcatct atatccttta taatttcatc taaagattta tctcctttat
    36361 ctatataaaa attagttgga tatatgctta taggtgatga atatgaagat tttattccat
    36421 ttcctgtagt ctttacacct gccttattag ccgtttttaa gttatgaagt aaagttataa
    36481 gctttccatt taaaacaact tcttttttaa atgtagctac tccttcatca tcaaaaggag
    36541 tagatgccat accattttct aaaagtgggt catcaactat tgtaactata ggagatgcta
    36601 tcatgtctcc ttctctattt ttcaataaag ataatccttt ttgagctgaa tctgcattaa
    36661 atatcccaga aaatgtgcta agcaaagata ccatagcttc attaagcaat atagttttat
    36721 atttacctga tggaatactc ttaccaccta ctttagataa agcattatca acaccaagtt
    36781 ttgatatctc acaaggtttt atttcttcaa tagaatttgc tctattatat cctattccat
    36841 catatttttg tccattgtct tctatgatag gaactacaaa ccctataagc atattagttt
    36901 tattgcttaa attaagacct ttagtattag atataccatt acttgataca gaataagata
    36961 tagtacattt agataaattt accaccttat ctgaataagc tttagtctct ctttccattt
    37021 ctaaagctaa atcaatcaac ttatctgcct ctaaattttc tagctcttta gaataagtct
    37081 ttacatcatt atagtgctta tctccttcat atataaattg tacatcttca ttttcaatag
    37141 tgtttactcc atcttttaca ttttttatca acatatcaac agctttatca tctaaaattt
    37201 ctgtataaga ataacctatc tttccattta ccttacctct aaaagataaa ccaaaagatt
    37261 tatcaagatt gtatttctca acttctcctt catatatatt tatacttaaa ttttctcctg
    37321 tataataata tatttcacac tcttcaaaac cttcacttag agccttttta aataatatat
    37381 ctttaaaatt tttaagttcc acaattatcc ctcctatctt ccacctacag taatttcttt
    37441 tacccttatc ataggttggc ctacattagt tggtatactt cctgatgatg agccacacat
    37501 cccctgagct tgttttacgt tattcccaac catatctata ttcataagta tatcgctacc
    37561 ttttccaatt aaactagcac ctctcactgg ctcttgtatt tctccatttt ttattaagta
    37621 accttctgaa actgcaaaat taaactctcc tgttacagga tttacagaac caccacccat
    37681 ttttttagca taaagtccat ctggtattga ctttataatg tcttctggtc tatcttctcc
    37741 agcagcaata taagtgttag tcatccttga agttggtgca aatttgtagt tctgtctacg
    37801 agaacttcct gtaggattca ttcccattcg tctaccatta agtttatcta tcatataaga
    37861 cttcaaaatt ccattttcaa tcagtatatt cttttgagtt ggatttcctt catcatctat
    37921 attcatagaa ccccagtagt ttggtattgt accatcatct atagctgtaa tctttgtgga
    37981 agcaatctgt tgacctaatt tatctgcaaa tacagagttc ccctttgcaa ctgatgtagc
    38041 ttccaaagaa tgtccacaag cttcatgaaa tattactcca ccaaatccat tatctattgc
    38101 taccatcata ttacctgcag gacaattttt agcatgcaac atagtatgcg ctactctagc
    38161 tgattctttt gcataatatt ctgggtctat ttcttcaaat atttcaaacc ctttacaacc
    38221 tccaggacct tcaaatccag tttgattttc attaccctta gatgcaattg aacttatccc
    38281 tagtctggtt cttattcttc tatcctcaac atatatacct tcagtgtttg caattaatat
    38341 tttttggtct ttatccaaat agctaacact tacttgagat atatcattac taaattcttt
    38401 tgcactctta tatgcaacct tcataacact tactttatct ctatttccta ttgaatttgg
    38461 ataaattttt atattatgta tgttatttat tttaatactg tcatttaata ttacactttt
    38521 tccatcttcc aatttaccta aagcaacagc agctttgtat gctacatcca acagactatt
    38581 taatgaattg tcacttgtat aagcatatat actcttcaat cctttaaata ttcttattcc
    38641 tataccataa tttcttccac ctattgcatt ttctacttta ttatcaatta aactaataga
    38701 attatttata gtgtcttctt caaaaatctc agcaaaatct cctccagtaa ttagacactt
    38761 ttctaatacc ttagaagcta tattttttga aagcataaat ttacctccta ctttaaattt
    38821 ttaattaact tttattcaat ctttttactt gttaacaaac attatatact atattactta
    38881 aaataaggta attatgaata tattatacat atgttttata ctaaaatgtt atcacatttt
    38941 atctatacat acccatataa ctagataatt aaaatgtata atattatttg ctatagaaaa
    39001 taatacactc atacataata aattttagga gtgaagtata tgaatcaaga atatgtaaaa
    39061 ggaaatccta tttttactaa tattaataaa gttccaagac aatttccata ccttactgat
    39121 gatattgata ctgatgttat aattgttggt ggtggcgtaa ctggatgtat ttgtgcttac
    39181 tatctagcta aaaacaatat aaagtctgtc attcttgaaa aaggaaggat tgcacatgga
    39241 agcactagcg tgacaacttc tctattacag tatgaattag atgacaattt gatagattta
    39301 acagaggtta tgactctaaa agatgctcta aaagcatata acctttgtac ttcagcactt
    39361 gaagaattag atacatttat aaagctatat ggaaataagt gtgattatgc caaaagagat
    39421 actctacttt atactgccaa caaacttgaa attaaggcta tcaaagaaga atataactta
    39481 agaaaagaaa atggatttga tgttgaatat attgatgaat ccacaaaccc ttttagcttt
    39541 gatttaaaat caggattgat agcaaagaat ggaggacgag aattagaccc atataaatat
    39601 agtcaccatt tgattgatgt aagtttaaaa aatggtcttc aagtatatga aaatacagaa
    39661 gtaaaaaaag tagatttatc aaatgataag gttactgctg aagtatcgta tggatacaaa
    39721 gttcatggta aaaaattaat tgtagctaca gggtacaata caagtttatt tacaaaaaga
    39781 aattttgcaa ctaagtcaaa tacttttaat atagcaacta aaccacttaa aaacatagct
    39841 tcttggaaaa acaacatttt aattagagat aactgtgacc catataatta tctaagaact
    39901 actaaagaca atcgattaat tataggtggt gaagatgtaa gttttgatga tatagaaaat
    39961 gaaactttag ccaatgaaaa gtatgatatt ttagaacaaa gattgaaaag tatgtttaag
    40021 gatataaaag acattgaagt tgaatataaa tattgtggtt gttttgcttc aactttagat
    40081 aatttaggtt ttattggtcc agataataaa aataacaatc tatggtattg cttaggttat
    40141 ggagcaaatg gtatactctt tgcaatatta ggaggtataa tgttaagtga attatatctt
    40201 ggcaaacaaa ataaaaatat gaaattattt aaagtagata gatttgataa atagatattg
    40261 tatattaaaa gactataaaa agatgaaact ttataattct aaaagttaac tttgatacag
    40321 tcttttataa tgttcctttt aaaaatactt tatttataat taaatataaa gtaaaatgtt
    40381 aaaatataac tgataaaatt tagtcataag ataatattta agtttatttg atgaaatatg
    40441 gaggaattat tatgaaagaa atactcgtta ttgctcccac taaaggaacc tatgaaaaat
    40501 caattcacat agttaaaaaa aacaaatata caaatattga tgttgtattt ggcaatctaa
    40561 aagaaggtat acctcttgct gaaaaaagta ttaatcatgg tactagaatt atcataagca
    40621 gaggtggaac ttacaatatg ttaaaagcta cttacaatat acctatagtt gaaattaaag
    40681 tagatgctta tgatattata aaaagttaca aagaggtaaa aaattccaac gaaccatttg
    40741 gaataattgg atttaataat gtcatctacg gtttcgatat tatagaagaa atattgaata
    40801 agaaaataac tatgattgaa attgaaaaag aagaagaaat ttatgatgct atagaaaagt
    40861 acagaaagaa aggtataaac acatatatag gagataccac tgttgcacat attgttaaga
    40921 gacttaattg taagggaata ttaatcgaat ctagagaaga aaacatactt agagccattc
    40981 aacaagcaga acaaatactc gaagcaacca aggatgaaca aaaaagaaga ttacagatag
    41041 aagctatgac agattttgta catgatggaa taataacagt tgataaaaat tttaaaataa
    41101 cattatttaa taagagtgct gaaaaaatat ttggtataaa aaaagaaaat gcactttatc
    41161 ataatgttgt agatgttatc ccaaacacag ttcttccaca agtagttgag actatggaac
    41221 ctcaaattgg tgaaatacaa aatataggga gtacaaaaat tattacaaat agagttccaa
    41281 taattgttga tggccagatt caaggggctg tttcaacatt tcaagatagc aaggagataa
    41341 gttcttttga acatacaata agaaggagct tattaagcaa aggtctatct gctaaataca
    41401 cttttgataa tataattcat gctagtgaaa agacaaaaga ttgtatagaa cttgcaaaaa
    41461 aatatgcttg ttatgatact cctatgatta ttactggaga atctggagtt ggtaaagaat
    41521 tattttgtca aagtatacat aactatagta agcgtaaaaa tgcacctttt gttgctgtaa
    41581 attgtgctgc catacctcca tctctaatag agagtgagtt ttttggttat gaggaaggtt
    41641 catttacagg tgctagaaaa aaaggtaaag caggtgtatt cgaactagca catgaaggta
    41701 caatcttcct agacgaaata agtgaaatcc ctcttgaact tcaaggtcga ttattgaggg
    41761 tattgcagga aaaacaagtt atgagaattg gtggtgataa agttattcct atagatgtaa
    41821 aaattatctg tgcttcaaat aaagacttaa aaaatatgat gcgcaatggt ttatttagac
    41881 aagaccttta ttttagaata aatatactaa cattatatct tccttcatta aaagaaagaa
    41941 aagaagatat tataaaatta tcagaatttt ttatacataa atattcaagc aaatacaata
    42001 aaacgccttt aattatcact ccaaatatta aaaaggcact tcttgaacga gaatatgaag
    42061 gtaatataag ggaattggaa ggtatgatgg aaagggctgt tattgtggaa tcatttgact
    42121 cgattttatt agaaaaggtt agcaatgaat atacaaataa tatagttgat aaagataata
    42181 gtgattttga atgcagtaat ttagatttaa aaactttaga aaaaaaatat atctataaaa
    42241 tttataacga aaataataga aatactacaa aaacctgtga aattctaaag ataactcgct
    42301 ccactctatg gcgtaagtta aaagaaatag aagatgatgt ttaaaaataa tacataccta
    42361 tatatatcaa aacgttttat gtttaatttt aatacataag gcgtttattt gttttcaata
    42421 aaaaatacaa ttatatgata aaaagaatct ttgtaagtga aattctcatc aatcatacct
    42481 ttaattataa gtaatctaca gcatttcaat cgattattaa aaataatcat gataactaaa
    42541 aatacaaact ctatatattg gcatagtaat tgcttttata atacctatat aaaaatgaaa
    42601 gggagtgata ctagatgcac atcttaaaat cagtgaaaaa gataccagga ggacttatgg
    42661 tctgtccctt gttattggga gcactattta atacagtatg tccacaagct cttgaaattg
    42721 gaggattcac aacatcctta tttaaaactg gtgcaatgag tatacttgct ctattttgtc
    42781 tatgcaatgg agctcaaatc aatatcaggc aagctggtaa gccattgact aaaggtatag
    42841 tacttacagc aacaaaattt ataattggtg cagtattagg tattattgtt agtaaattta
    42901 ttggacctaa aggtataatt ggtattacac ctcttgccat agttgctacc atgactaatt
    42961 caaatggagg tctatttgct gctcttgcag gtgaatatgg tgactccaca gatgttggag
    43021 caatatctat cttatctcta aatgatggtc ctttttttac aatgcttgct tttggagtaa
    43081 ctggacttgc aaatgtacct atagtagcac tatttgcagc acttatacca atactacttg
    43141 gatttatact tggtaacctt gatgaagata tacgagaatt tcttgcacct ggtacaacat
    43201 tattaattcc tttcttcgct tttcctttag gagcagcatt aaactttaat caaattataa
    43261 ctgctggact acctggagtt gtacttggtt taggagttac tataataaca ggtatgggtg
    43321 gctactttgt aatgaaactt atacgtgcag aacatccagc agtaggtgca gctacaggta
    43381 caacagccgg aaatgcagct ggtactcctg aagctttagc agctatagac cctactctag
    43441 ctacaatagc agctgtttca acagtacagg ttgctgctgc tattattgtt acagcaatat
    43501 gttgtccaat gttagtttcc tatctagata aaagagaaaa aaagaaaaaa tctattttta
    43561 aaacaaataa aaatattgaa gtaaattaat acttaaggag gtaaaattaa tgaatgcaat
    43621 tattcatgca aatgaaaaag ataatctagt tacatgtgtc agacctttag ttaaaggtga
    43681 aaaagtttca attgatggaa agtcttacat agtaaatgat aatatacctg tctttcataa
    43741 gatggctaca gaagatgtaa aaaaaggtga tgttgtatac aaatacggtg aaattatagg
    43801 aattgcaaca gttgacataa aaactggtga ctatgttcat gtacataaca ttgaaagtac
    43861 acgtggtcgt ggagataaaa aataggagga agttaaaatg aaattaatgg gttatttaag
    43921 agaaaatggt cagtttggta ttcgtaatca tgttttaatt attccaacat ctgtatgttc
    43981 aagtgagaca gctacaagaa tagcatcact tgtgcctgga gcaatagcaa tccctcatca
    44041 acatggatgt tgtcaaattg gttctgatat agagcttaca gcaaagacat taataggatt
    44101 tggaaaaaat cctaatgttg ccgcagtttt agtagttggt cttggatgtg atggtattca
    44161 agcaaaagaa ttagcatctg aaatagctac aacaggaaaa aaggtagatt acgttgttat
    44221 acaagaatgt ggtggaacat taaaaacagt ttctaaggga actgaaatag taagtaaaat
    44281 ggctcgtgaa gtatcaaaag aagtaagagt tgaatttggt atgagtgaaa ttacattagc
    44341 acttgaatgt ggtggttctg acccaacaag tggaatagct tcaaaccctt caataggcgt
    44401 tgcatcaaac cttcttgtag atgaaggtgg aagtagcata ctaagtgaga ctacagaagt
    44461 aattggtgca gaacatttgt tggctacccg ttttgaagat gaagaaatga aagataagtt
    44521 tcttaaattt gtaagtgatg tagaaaaaag agcaattgct atgggagaag atttacgtag
    44581 tggtcaacct actccaggta ataaagctgg tggactttca acaattgaag aaaaatcact
    44641 tgggtgtatg tataaggcag gcaataagcc attcaaaggt gctcttgaat atgctgatat
    44701 tgtacctcct gataaaaaag gattatattt tatggatact ccaggtcaag atatagattc
    44761 tatcactggt atggtagcag gtggtgcaca aattgtaatc ttttcaactg gtagaggtac
    44821 tccaacagga agccctattt caccagttat taaaatcact gggaatagtg atacatacaa
    44881 caaaatgcca gacaatatcg atataaatgc aggtagaatt ataacagatg gtgctaaaat
    44941 agcagatata ggtcaagaaa tatttaatga aataatagaa gtctgtaatg gtaaacatac
    45001 caaagctgaa agtcttggtc atagagaatt tggcatttac agaatttcat ctacatttta
    45061 gattgtaaca aaatatcttt tataaatata atacttatgt agatacataa gctaaaagtt
    45121 ctttctaatc ctataaaaat tttctatact gaaaaggaac tgtatcaaaa ttattttgaa
    45181 aacagttcct tttttaacct cttttactca aaatattata aaataagatt taaacaataa
    45241 acgtgtcttg attaatctct aagaagacat aaataaagct aaatgtaaag tgagataaat
    45301 aaaatttaat atctttgtat gaaaagatat ttggtataat atgtctgaga gaattcttat
    45361 ttgtaaacaa ataaaggatg gaggatgaaa caaaagaatg aactttgaaa acacaaaaaa
    45421 taaaaaaata atagctactt tactattgac actcctttta atcgtgtcat taacatgtgt
    45481 caattttatt atgaatctaa ataaagtaac acataatgaa acagaacgat atcttgtaga
    45541 agtttcacaa agtatttcca ctacaattaa tgtgaaatgt aaaagtatat ttaggacact
    45601 atattctatg ggagatactt attttgagat taatgatagt gaaaaagaag tcaatagata
    45661 cttatcaaaa aaattaaaat tatttgaatt tgattggtta ggtattatag attctaatgg
    45721 aaattttgta agtgccctta aagatacagg taatgttaaa ggacaagact tttatagaaa
    45781 agcccttcaa ggtaaagaaa caattactcc tgttaaatca caatctggta catatggaat
    45841 tttatattct gtaccactat acaatggcga taaaattgtt ggagctgttg ctgcttggaa
    45901 tactattgat actatgagaa atttattaag tgtagaaagc tttcatggtg aaggattttc
    45961 ccaaattatc gaccaagatg gaaattttat tgtaagttca gcaaacaaaa atgctccaaa
    46021 aaatgtggta aatttttttg acatgattaa acaccaagga aaacaggttg ataaaaataa
    46081 acttgaagaa atgaaaataa acttaaaaaa gaacaaaact ggttctatgt attatacatt
    46141 aaatgatggt atttctaagg caatgcatta tcttccatta caagaagaaa acttatacct
    46201 cctttcagtt gttccaacaa aaacagcaag tgcacagttt gatttacttc taaaaaaagc
    46261 aatcttcatc aatattttaa ttgttatact atttttattg cttattatat tgattatgtt
    46321 tataaatcaa aagaacaggg cacaacttat aaaaatcgcc tatgtagact ctgtaactaa
    46381 aggttacagt aaagcacgtt ttgatattga agctaaaaaa attatacagt catcttcatc
    46441 agaaagctat tcattggtat ctataaatat tcagaaattc aaacttatta atgattcttt
    46501 tggtagtgaa gcaggagata aaacattaaa gtacatacat gatgtcatta gtaattatct
    46561 agaaccagga gaattgcttt gtcgagtttc taatgaccag tttaatgtac ttattaaaac
    46621 tattcctcaa aaagaaattc ttaagtacat agaaaatatc accaatgata ttaatagttt
    46681 caataaaaat gaagaatgta aatattttat agctctatct ataggtgtat ataaaattga
    46741 tgacccaaat ctacctttag tttcaattca agaccgtgca aatgttgcac gaaaaaataa
    46801 taaaggaaac attggaaatc atccacttta tacatgtgtt ttttatagtg atttagagcg
    46861 tttaaaaatg attaaagaaa aagaaatgga aaatagaatg gaggaagcat taaataataa
    46921 cgaatttata gtatatcttc agcctaaaat aagcctcaaa gataatacta ttgtaggtgc
    46981 agaagcatta gtaagatggc aagacccaaa taaaggcctt ataccaccag acgagtttat
    47041 tcctttcttt gaaaaaaatg gttttattac aaaactcgac cactatgttt ttgaaaaagt
    47101 atgtagtatg ataagaaaat ggatagataa tggagaaact ccaatgcctg tttcagttaa
    47161 tttttcacgt gctaatttaa ataatataga ttttttagaa aaatacagaa tgcttcgtaa
    47221 taaatacaac attcctgcta agctcttaga aattgaatta actgaaacac ttgtatttga
    47281 aaatctccaa aaattaatta atataataga ccaaatccat gaagaaggtt ttcaatgttc
    47341 actagatgac tttggaagtg gatactcttc actcaatatg ttaaaagaaa taaaagttga
    47401 cacatataaa acttgaccgt gcttttttta gctcacctaa tgcagataat attgctgaaa
    47461 atcatgtaat agaatctata gttaatttgg caaaaaaatt aaatatgaat agtatatcag
    47521 aaggtgttga aacaatcttg caaatggatt atcttaaaaa aattaattgt gatatgatac
    47581 aaggatatgt tttttcaaaa cctctgcctc aagaaatatt tgagaaaatg acttttggaa
    47641 aaaaactaga agaaaccagt atggatagtt ccgtttaaat aaaataaaaa acttgtctct
    47701 ataaaataat tttaatcatt ttataaagac aagtcttttt attttccaat ttaattttat
    47761 tttctaaatt tcttatactc ggcttgtttt aaattccctt tttaagaata ataatacgat
    47821 tatcatagca ataaaatctg caactggctg tgccaaccaa acaccatcta aattaaattg
    47881 aattggaagt acaatgatta atggtataaa taaaataaat tgtcttaaaa gagttaaaaa
    47941 cattgaatgt ttaactttac ttatacactg aaaatacaca ggtcctacaa tagaaatccc
    48001 cattataggc aatgtaatta gatttatgct tatacctctt actgctatat ccatcaaatc
    48061 tgaatcttta ttaaatatac ctacaaatac ttctgggaaa acttgtacta ttaaaaatcc
    48121 aaatgacaat atgacaactg acactatgat agataatatt aaagttttct ttgcacgttc
    48181 atattgtttt gcaccataat tgtatgatat tatagtttgc ataccttgat tcaatccaaa
    48241 cacaggcatc ataaacatca ataaaataga tgtaagtgct gtcatagccc caatagctaa
    48301 atctccacca taaaccttta gagaattgtt tgtaaacatg tgagttatac ttatagctac
    48361 ttccatagca aaaggtgtca ttcctattgc aaataccttc tttactatat ctttattcaa
    48421 ttttaagtta cattttttta gttttaaagt ggacttccct cttataaaat aatatgttac
    48481 ccaaaagaat actactattt gacatagtac tgttgctata gctgctcctt ttatacctaa
    48541 attaaacaca aatataaata tagggtccaa tatcaggttt aatacacatc ctacaatcat
    48601 tgtccttgct gctaattttg gattaccttc tgctctaatt gcattattaa gagaaaatgc
    48661 aactaaatta aatatacttc caatcaatat gacactcata tagtcttttg cataaaatat
    48721 tgaatcttta cttgcaccca aaataaaaag tatatcttct aagaaaacta atcctaatat
    48781 agttataatt aaagagataa ttatagataa tgtcaaagca ttacctaata tcttctctgc
    48841 ttcttctcta tttctttccc ctaattttat agacaatctt gtgctagcac ctactgatac
    48901 caacattcca aaagctatta ttagagtaaa tactggcata gttacaccaa gacctgcaat
    48961 agctatagag ccaatacctt ccatagaacc aataaaagct ctatctacta cattataaag
    49021 tgaagttacc atcattgcta ttattgccgg tatcgaatac ctaaataata aaatccatat
    49081 tttttcatgt cttaatgctt cttgattctc catgttgtca ccatttacac catgtcataa
    49141 gttatacaaa ttggtttatt tgttcttggg tctgttgcta tttctgcatc aatattaaat
    49201 aattctttta gattatcctt cgtcataaca tcatatgcat caccttcaca aactatttta
    49261 cctttcttaa tacctatcat gtggtcagca aatcttgctg cattattaag ttcatgtatt
    49321 accatgacaa tagttcttcc ttgtttttta tttagttcat ctaataattt tagtatctct
    49381 aattgatgtg ccaaatctaa atatgttgta ggctcatcca gtaataatat atcagtttct
    49441 tgtgccaaag ccatagctat ccatgccctt tgtctttgtc ctcctgataa atcttccata
    49501 tttctatcct taaattctgc aattccagta acttctaaac tccaatttac aatctctctg
    49561 tcttctttac tagaattacc aaatccactt ttatgaggaa atcttccata agaaattaat
    49621 tctgaaacgg taagaccact aggagcttga gggctttgtg gaagtacagc catatccttt
    49681 gctatttctt tagacttctt tttgtagatg tcctctccat ttatatatat tttcccacta
    49741 ttagggctaa taattctacc tatagtttta agtattgtcg attttccaca accattagcc
    49801 cctatgatgg tagttatttt tccttttggt atatttaaat ttaaattttt tataatatct
    49861 gtgtttccat atgatacatt tagattctta gtatttatac agttcataac aacacccttt
    49921 cctaatcatt taccaacatt aaataaataa agtacggcac tcctattata gaaactacta
    49981 tacctactgg tatttctata ggtgctagaa gatttcttga tatagtatct gctattaaaa
    50041 gtaataatgt tcctatcaat gctgatactg gtattaatct tttatgcttt ggtcctatta
    50101 tttttctacc tatatgtgga gctattaaac ctaaaaatga aatactacct gctactgctg
    50161 tcgatacacc agataaaatt actgcatata ttataagtct tcttctttgt ttttctacat
    50221 ctacaccaag acttatagat acttcatcac ccaaatttaa aacatctata tatttagatt
    50281 tataaatagt tatacccata aaaatcacta taaatggaag cacagctatt acatatttcc
    50341 aactggttcc ccaaatgctt cctgatgtcc atgccataac cctattaaat tcttgtgttg
    50401 taaatttcaa ttggaatatc gtcaaaattg aagtaaaagc tatgtttaca cctataccaa
    50461 taagtagtaa tcttgacgaa tttataccac ctttccatgc aagagaatat ataagaaatg
    50521 ctccaaataa agctcctata agtgcaacaa taggcattgt aaatacagtc aagttactca
    50581 taccttcata tacattacca ttcataaggt atatataaac tactacaaac aatgcagcac
    50641 ctgaatttat tcccaaaatt ccagaatcag ctaaatcatt ctttgtaact ccttgaagta
    50701 ttacacctgc tgttgataat gcagaaccaa ccaaaagtgc tattactatt cttggtaatc
    50761 ttaatttaaa tattgcaatt tcatgattac gctgaccctg ccctaaaaaa gtctttataa
    50821 catccattgg ttctatagaa aatgagccca tatttaaact caataaaaaa gtgataaaaa
    50881 taagcaccat taaaattgat ataacaagta atgttttaga atttattttt ataatatttt
    50941 tcatagtacc tatttctccc cctttctaac aaggtatata aatattggca ctcctataag
    51001 tgctgttata gaacctactg gtgtctcata tggaggattt atcatcctac ttaatatatc
    51061 tgtatataca agcaatacag ctcctaatac taaagagctc ggtattatat acttataatc
    51121 tgaacctact attcctttag ctatttgagg aactataaga cctataaaaa taatattacc
    51181 agacactgac acagatgctc cagtcattaa tattacaagt actatacata taaatctaac
    51241 aaagttagtt ttttgtccta atcctattgc cacttcttct ccaagactta atatagttat
    51301 tcttggagcc ataataatag ctaaaataaa tccaatacca ccagctacaa atagcaattt
    51361 tataccttcc cacttcactc ctacaagccc tcctgatatc cagaaactta attgttgaga
    51421 taggttaaaa tacatagata ttgctgatgc caaagaaatt agcaatgtac caagagcgac
    51481 tcctgcaaga gctaatttta cattattaac tcttcctctt gatttagaac ttataaaata
    51541 tataaataat ccacttatac ttgctccaat aaatgcaaac atcattacac taaaacttcc
    51601 atgtataagt tgaggaagtt ttttttgaag taccagtgat atcgaaattg cgaatgtagc
    51661 tccttgtgta attcctataa cagatggttc agctatagga tttctcgtta ttccttgcat
    51721 tattgcccca gaaactgcta aaaaccctcc aacaagtgca gctgctattg ctcttggaag
    51781 tctaacatcc tttactattc tcatatttat tccatcttcc atttttatca aactatctat
    51841 gacagttgat agattcatat cttttgcccc aatagttatg gataatacaa ttccaaatac
    51901 aagtacaact atacttacta atatcaacaa ataagttata ttttttttac tcagcttagt
    51961 caattatcct acctcctttt cccttttaat cgtcagtata atatcatcta ttaagtattt
    52021 taattttaag atttattaaa aataggtgtg aaaaatgaat atcattatct cacacctact
    52081 aagttaagaa ttactttgtt aattcatttt taactgattc taataataac tcttttccaa
    52141 ttggattgta tgattgactg aaaaatggag cagcatcaag tattgttaca ttaccatctt
    52201 ttactgctct tatttgagac cagatagcac tattttctaa atctttttta tctgcttctg
    52261 tagcaattac aactatatgg tctgcatcta tatctgttaa accttccata cttaccattg
    52321 gtagtgttat tccatcctgt tttggcatat tcttaggtct agctaatttc atatcatcat
    52381 tgattagagt acctattcca ccatcactaa ataccataaa ttgacctgaa cttgccaaca
    52441 ctggtaaata agttttttct ccattctttt ctataacttc cttacctaac tttgtagctt
    52501 tttcatcata cttctgtagc caacttttag cttcttcttc tttgtcaaat aactttgaaa
    52561 catcagttaa cttgcttctc cagtcatttg cataatcttt catcataact acaggagcta
    52621 tttcttttaa ttggtcatat attttttctt gtctttgact cattattatt aaatcaggat
    52681 ttacttctaa tatagcttcc atatccatag tatccatcat tgagtgccca actatcttta
    52741 cacctttaag ctcttctctt atgtaacttg gtaatttatc agtttcatat gagtctacat
    52801 ttgctgttgc aacaggctta taacctgcta ataatagttc ttcactactt cctgatatat
    52861 caactatttt tttaggattt gatggtatct taacctctcc tttaacagat tgtacaactc
    52921 ttgtctctga tttatcttta tcctctgtat tcttatctga acatgctgta acaagtacta
    52981 acgtagttat aatagatata aatattgcaa gtgattttat ttttttcatg attacttctc
    53041 ctacttgttt attatactta catgatattg attatcataa gcacatattt attatagcat
    53101 ttttctattt ttagtcaata ttattttgta aaaggataaa aattcctaat taatcttaat
    53161 tatatatagc ttagataagg ttttcttata ttaaacagta ttttttttaa gaattggaca
    53221 caaacacaat gacttttagg ttaaacaatg ataaaatgca atttatagat aatgaattta
    53281 gtaaggagga ttcaaaacat ggtacattta gtatattgtg ataatgcagg aaaaaaagga
    53341 gaaaaggtct tagataaaat cttggctgga acaaaaacaa tggttattag aggtgctgct
    53401 ggtagaaaaa taccacatag tagagtattt gaagatgagt tactttattt tatggaaaaa
    53461 ggaactggaa aaatatctgc aaaagccact gttaaaaaag tagaaaacta tgttaaatta
    53521 acagaagatg aaatttctaa aattttaaat gaaaatcaac caaaattaaa tttatctgaa
    53581 aagcaaaaag ttcgttggca taaaaaatgt ttatgcttag ttgaatttga aaatgttgaa
    53641 gaaataacac ctcttgattt tgaccatcaa ggaaatatgg atgattggct tattgttgaa
    53701 aaaattgaag atgtagttgt tggtactagt ataccttaca attatgagaa gtctaaattt
    53761 taaagtatca ataacataat actatattgc taaactctac ttaaataaaa aaagagtgca
    53821 tttaataatt ataaaaatta tttttataca ctctttttta ataataaatt taaattactt
    53881 actttctaat ctttcatata catctataaa ttcttctgct aattgttgaa aattcatagc
    53941 tgtcattaaa tggtcttgtg catgaataag tataacactt atttcagttt tattaccatt
    54001 agcttcattt tgtatcaatt ctgtttggaa tttatgagct ttatgaattg attctttcga
    54061 cttttcaata cattctctag ctttatctat attcccgctc tttgcttctt ttattgcttc
    54121 aaatgctagc cctttcgcat cacctgcaaa tccaattatt ccaaaagata tctctatcat
    54181 cttctcatcc atttattcga cctcctaaat atctctatag cttgatatga ctaatccatt
    54241 cttttctaaa aattctttga cttttttaga tgtaagtatc ttgtgctctt tcgttctatc
    54301 aatagcataa gatgtagaat ttaaaatata atcatctaaa aaagctgggt gagacataat
    54361 atccactaca tcatacttca ttatttcgtc tatatttttt ataaaatatt cttcacttac
    54421 attttcctta taaaaactat ctattaaagg aactacttta gaatactcta aattatattc
    54481 aaatccacct cttattggaa gattatactt ggttacaatc ttctctacta ctggctttaa
    54541 acttactaaa gtatggatat gatggtgact atctaaatga gatatatcta ttccaagccc
    54601 ttttacccta tctatttgag cacaaagttc tctataaatc tcatcacaat ccattttttc
    54661 aataatttcg tctgtaatcc tcctaataaa aaaaccgtct ttatcaacaa tagtttttaa
    54721 gttagataat aatggtctac cacaacttaa agtcatatga actccacaat ttaaagtttt
    54781 attttcttta agtaagccta ctccatgttc taccccaggc atatttgcca tcatagaagt
    54841 agacctaact ataccattat tatgagctga aattattcca tagttcacag cttcacaata
    54901 tccaaaatca tctgcattta ttataatttt agtcatacca taacctactt tctatagaca
    54961 actatctatt aaatctagga agataatctt tatgagcttc caacatttcg tctaatatag
    55021 tttttgctaa gtcatcagat ggaatcaatg ggtttataca aagtgccaaa agagcagatt
    55081 cataatcgcc atatacagct gctttagcta ccaatacttc aaatgatttg atttggctta
    55141 ctaatccatg cacagaatct ggtaaatatc ctatacttat tggttttgga ccatttttgg
    55201 ttattacact actcacttct accgcttgtt catctttaaa atctcttata gaaccattgt
    55261 ttaatgtatt aactacttgg atatcttttt tgtcattgta tatagaactt attaaattac
    55321 aagcagcatc actatagtaa gcccctcctc ttttttcaag ttgaggtggt tttacatcta
    55381 atttttcatc cttatataat tcaaataatt gttcttccaa ttctttaact acttgacctc
    55441 tagcttttcc ctctttaaac tctctcaact catcctcaag catttcttta gttttatagt
    55501 agtatctatg atatggacaa ggtattgcac ccaaagattt tacaaattca gcattaaaat
    55561 caattgcctt tatattttgc atacttatat ctgctttgac aaacttatca attgcttctt
    55621 ttgtaacatc ttctccatct aaagatacat ttagaccata aaccatatga ttaagacctg
    55681 caaaatccat acttattctg tcactttcta cattaaatag tttggcaaca tcatttttta
    55741 aatgaattgg cacattgcat agacctatat atcttctaaa attagtatat ttgaatacag
    55801 cctctgttat tattcctgtt ggatttgtaa aattcaccat ccatgcattt ggacataatt
    55861 cttccacatc ttttattata tcaaatataa ctggtattgt gcgaagggct ttaaataaac
    55921 ctccagcacc attagtttcc tgccccataa ctccatgaga taaaggaata gtttcatctt
    55981 ttattctcgc atctaaaaga cctactctaa gttgtgttgt cacaaagtct gcatctctta
    56041 gagcttctct tctatctaaa gtaagattta ttttcatatc tactccagct ttttttacca
    56101 tcctcttagc tagatttcca actatctcta atttttcttt tccagcttct atatctacaa
    56161 gccataattc ctttacaggt aactcttcat atctatttat aaaaccctct acaagctcag
    56221 gagtataact tgaacctcct ccaattgtaa ctatttttag tccctttttc atctcattat
    56281 accatcctta cctataattt aatatactct acaaaaccct atacatttat ttaccgaaat
    56341 aaaactacct agttgttaat tttcaattta ttagcttcca ttttttcaga cgctatgaca
    56401 aatggaatat atattaatat tgataatatt aaattaaata gtgctaaagc tccaccagtc
    56461 cagtcacctg tagccatcgc tccacctaat ataggaggtg ttacccaagg tattttaggt
    56521 aaaattactg gtgctactaa tccaaaatct attgctaagt atgatacagc actacatatc
    56581 actggtgcaa gtacaaatgg aatcataaat ataggattta aaactattgg aagtccgaat
    56641 atcaatggtt ctcctatatt aaatattgca ggtggcccac ctaatactat catttcttta
    56701 cgtcttctcc cagctattaa taaagctact attaatccca ataccattcc agaaccacct
    56761 aaatatacaa atgcatcaaa gaatgcacct gcaagtacat ggtatccttc cgttgctcct
    56821 gcttgagcca aggcagcatt ttctccacct aatttcataa gtatagtttc tgtaaaagga
    56881 agtgctatat ttgcaccatg aagtccaaca gtccaaagta tatgaattat aaatgcaata
    56941 agcattgtag aacctagact atcagctaca tttgatagcg gtgctcctaa ataagtattt
    57001 aaaatatctg ttaagaaact tccattagaa agcattttta taaatattcc tattacagta
    57061 aatatcatta tagttaacat tcctggtatt aactttgcaa atgatcttga aactgctggt
    57121 ggaactccat ctggcatttt tatagttaat ttctttacct tagataatct tacaaatatc
    57181 tcagttgata ataatcctat taatatagaa gagaataaag ctgctgtacc taagtaggtt
    57241 tgttgtatca ttccccatcc ttcaactact gtagttcctc cctcaggaac tattttacca
    57301 atttgtggag ccattataaa aaagatagat aaagctataa gcccagattg taacccatca
    57361 ctctcataag attttgctag aaaataagca acacctatta ctaagaatac tgccattgta
    57421 cctattgctc cccaccaaag gtcgcctcca aatgtggtcc aattttctcc aaatatactt
    57481 gccatcaaat ttttgtatgc ttccaatggt aagttattta tcaatgttcc caaggcacct
    57541 accatagtta taggtatcat tactataaat gcatctctta ctgctactaa gtgcctttga
    57601 gctcctattt tagcagctac aggcactata tatttatcca taaatgacat gaatttttcc
    57661 attttacatc ctccagtaca actttatttt gaactattta actctacagc tctatctaac
    57721 acagcttttc cattacatct tccataatcc atcatattta taacttctac tggaatatta
    57781 tatggttttg ccatttcagt tgcttttcct aatacatatc taacttgagg ccctaaaagt
    57841 aagacatcac aattttctat ttcatttttt aagttcactt ctgatatagc ccatattttt
    57901 gcttctatac cgttttcctt tgctgcatcc tccatttttg taactaataa actagttgac
    57961 attcctgctg aacaagctaa cattattttt atcatttttt cccctccaaa ttagattcat
    58021 taaatatttt ttaagtcata aattttttaa actatacatt taaaatatgc ttttctatta
    58081 attttttctt aatgtatata tcttattttt aaatgtatat acatttaatt cttgatatta
    58141 ttatatacca aatgtatata catttcaaga aaactttttc attttattta aattttattc
    58201 gacaacagca ttcaaagtta atgtatatcc atagtgatat gtgtgtgagt actcaaaaat
    58261 ctcactattt tgtaacttac aaatttggct tatatataaa agtggctctg gttcttctaa
    58321 ttttagatta tccatacatt cttcattcga tattacagct tgtacttctc tctctgacat
    58381 ggctatcttg tatccacaca cttcttcaac aaaattataa agagaatttt cacaatgagt
    58441 cttatttaaa tttggaaata acttaactgg catataagta atcatatatg aaactcttgc
    58501 atcattggct aatcttactc tttttatttc ccaaacattt tcttctaaac ttatattcaa
    58561 cttacttgat aaattttcat ctgcctgaac tatttcaaga gataccaata tattagatac
    58621 tttatagcct ttactttcca tctctttagt aaatccactt acagacgata tattatcata
    58681 tatattattt gcaataacta tactacctac acctctttgt ctagtcatat agccttcttt
    58741 aactagatta ttaagtgcag accttacagt cattctagtt acattaaatt cttcactcag
    58801 ctgtttttca gaagggatta aatccccttc tttcaaactg tctgaattta ttaactctct
    58861 aacatgattt tctataactt tataaattgg ctctttcatt taattcactc cttattaatt
    58921 aaatctttta tataataaga taattttata tacaaataaa gaaaatgtct atacatttaa
    58981 gataatttaa attttattca gacatcttgt acaactttcc gagttttaat aaagatataa
    59041 atagacttat cattaatata ccttttaata tacttgataa ggttatactc caccatacac
    59101 catttagacc caacatttct ggtctagata taaagtaagc caatggtact cttgcaccag
    59161 tcagtatagt aattataata gaaggtatat aggttctgcc taatcctttg aaagctcctg
    59221 ttgttattat ttctaaacac ataaaaaatt gagaatagcc taatatttta agataaattg
    59281 ctcctttttc tattgcctca ctttcatcta taaaaataga aaatatactc tctcctgcaa
    59341 atactaatac caaagtagtt attatcccaa gtacagaaga tacagttata gctattttgc
    59401 aacctttatt tattctagaa tacttcttgg caccataatt ttgtccaaca aaactgccta
    59461 atgcaactga tagcccttca gccgtcatcc aggaaattgc ttctatttgt gagcctactt
    59521 tttgtactgc aacagccaca ggcccccatg atgctactat tactcctaat agcattgaga
    59581 atactgtaaa cataccactt tgtattgcta taggtaatcc caatttatac agaactttat
    59641 aatatttagt ctctatttct ttaaatagtc ttaatttaaa atattcttct ttacttttaa
    59701 ctattatata tataaaacat gtagtaacta ctatctgagc aaatacagtt gcaatagcag
    59761 ctcctgcaac accaagtttt ggagcaaatc cccatccaaa aattaatata ggatcaagta
    59821 taatattagt tattaatcct actgtattaa tacgaaaagg agttttacta tttccaagac
    59881 cgttgaaaat tgcagtaaat actggattaa taaaataaaa taccatacct agagctacta
    59941 ttatcaaata ctgtctagac atggttataa cttctaagtc tcctaatcta aaaaaaccta
    60001 tcaattgttt attaagtact attaaagaaa ttgtatatat tattgctagt ataatattta
    60061 tttctattgc tgacttcata tatgatttag tagtgcttat attatttgca ccaatacttt
    60121 gtgctacttt tatctctcca cctacttttg aaatcataat aaatgccatt gcaagccatg
    60181 gaaaaaaacc agctgttcca actgcagcta ctgctttact tccggcttta ccaacccata
    60241 tcatatctat catgttatac cccatctgta taaatgaagt ccccattatt ggaagtgata
    60301 gcttaagtaa tttttctgta attcttcctt ctgttaaatt aattctgtct ttcattttcc
    60361 acctctttta tattaaattt atttgcttat atagctagat taatcatttt atttgattga
    60421 gttcactatc cttcaattta tattatcata tctcaagatt gcatctcaac catacttatg
    60481 tttaagataa agtattttac ctatctctga taaaattaat acttatgaat ataaatatag
    60541 tcatttcatc aatacatatt ataaccctta acttaacttc aattaagtat acatactgta
    60601 atcaattaga atattttata atgtatcttc cattaagaaa taacaaatat aagtgattta
    60661 tctataattt tatttataca taaaatagta tactgcaata ataaaaaaac tatatttgaa
    60721 tactttaagc atgtttacta attgtaattt ccacacaaat ttgataatat atgaatatat
    60781 tatggtgaaa tttatagata tatattaatt atggggagat tgtgggaggt tcttttcaca
    60841 agacatttaa gctatgaaaa taaataaaaa atttaataga gttgatatgc aggtttcaat
    60901 acttactgca attattgtaa taatatcttc ctcatgtgta tattttttta attatacatt
    60961 aacttataag agcatgatat actctttaag tgagaggtca aaacatatct atgaatatgt
    61021 agagagaaat attgataaaa atacctttac tgaaattaat tctaaagaag accaatcaaa
    61081 aaagtcttat aaaagttcta aaatcctatt agaatctgta aaaaatacta ctggagtcat
    61141 gtatctatat actgctaaaa aaacaaaaga tggatcacta gtatatgttg ttgatggttt
    61201 aaattcatct agaagtgatt ttagaaatgc tggtgatttg atagaaaaag agatttgggg
    61261 agatcttaac aaagcattag ataatcatat attgttacct aaaaagatta aatcaacatc
    61321 ttggggatac atatttatat cgtattttcc tattcacaat gatgttggta aggttgttgg
    61381 agtaatagga attgaatttg aagcaaaaca tcaatacaat acatttaaat ttataagtat
    61441 agttacacca ataatagcat tattaacttg tctaatatca gcattgattg cagtgattct
    61501 atttaaaaga atatctaatc ctacatatac tgattttgct aatacagatt atttaacagg
    61561 cctaaaaaat agaaatgctt ttgaaataga tatgaataac ttaaacaatt caaatctaaa
    61621 gaatctaata tctatcatat caatagattt agacggttta aaaaagatta atgataaatt
    61681 tggccatcag acaggagact tatatattaa gcaagcaagt aaaattatac aagatgtaat
    61741 aaataaaaaa tatatagttt atcgtattgg aggtgatgaa tacataatta ttctaaaaaa
    61801 tttatctcac aaagaaataa atagtattat aaataatatt aatttaaaaa tagttgaaga
    61861 aaactcaact aatgaattaa aattatcaat gtctattgga tatgctattt ttgatgaaaa
    61921 agtagatgtt tctttatttg atacatatcg tcgtgcagat tctcaaatgt atgataacaa
    61981 aaagaaaatt aataaataat atcaataata aatttaaaaa gtctattctt taaataataa
    62041 atcataagaa tagacttttt aaatttgtgt ttttataaga taaattattt aattaaagtt
    62101 tgttcttttt tctaaacgat tctttataaa ttcatatatt actttcacta atatatttgt
    62161 gactaatatt aacacagcta gtgctgctgc ctgtgcagta ctccccttat catctagttg
    62221 tacaattgat attgcagcta cttttgaact tgcagtatat ataaaaacta gtgctgatat
    62281 tgtcaccata gagtttagaa aaaagtacat aaagttctct aaaactgctg gcaaacaaag
    62341 tggtatagtt acgttcttaa gaattgatgc gctgtttatt cccattgatt tagctaccat
    62401 gtccaattct ttatctactt tcttaatagc agtagtagct gttataaatg ctactgaaaa
    62461 gaaatgaact atattacata taaccattat aagtaatgtt ccatataatc cattaaacaa
    62521 atttttaatg tatattgtat ccataaaatt aaactctaat ttattaaaaa ataatacata
    62581 agctatacct aaaactaatc ctggcaatgc cataggcaat gtacttaaaa aatacccaaa
    62641 tgattttaaa tatggagctt tttctgtttt ttcatttaaa tatgcaaata agaaaacaaa
    62701 gctcgtccct agaatagctg tcaatagtga catttttatt gaatttataa atggtttaat
    62761 tccatcaata ctgtttttca tagaaaagtg ttccagtgta agtcttaaat catatggcca
    62821 aactgatatt aatgaggata agattacagt taacattaca gctattatac caaatgcaat
    62881 aattcctaca acccctccta aaatactatc tcttaactta ttagttttaa ccttatatgg
    62941 aattgacttt gaagttatat atgagttttg atttttttca atttttttag ttactataaa
    63001 cgatattatt gcaggtatta aaagtaatat tgatacagtt gctcccattg gcatattctg
    63061 ttgccctata atttgcttat atacatctat tgataataca ttaaactctc ctcctatcac
    63121 ctttggagct ccaaaatctg taaaacataa tgtaaatgat acgaatgcag aacttattaa
    63181 agagtatttt atacttggga ttgttatgct tataaattct cttatcttgc ttatccccat
    63241 agtattacta gcttcatata gtctataatc ggttgaactt agagatatat aaagtatttg
    63301 aaaggattga ggaaatacat atataatttg tgccaatatt attcccactg ctccatatat
    63361 tggaacatgc actccaagta aattagttac caaaccttga tttccaaata aatatactag
    63421 acctattgca tgcatcattg ttggagcaaa cataggaaac atagctaatg atttaaaaaa
    63481 acctttaaat ttaatctttg ttctagttaa tgcatatgca tatactaatg caagtgttag
    63541 tgatattaca gttgatataa ctgatacaaa tactgtattt tttagagaat ttaatagaga
    63601 ttcagaagcc aagtattctt gaaagttttg taatcctaca aagactccat ctttatctaa
    63661 aaaagcctgt acaaatagat atattatagg tgctaataaa aatattacta aagacataac
    63721 taatactgta agcatacatt tttttatatc taaattcatt tttgatttaa gacttatact
    63781 tttagaactt atagcattat tattcataca cttatgctcc tttaactttt ggatacttta
    63841 aatagtattt ttcgtctata cttattttta caaggtcacc ttctactaaa tttaaattaa
    63901 cccactcttt tatagaaaca tcacttatta tgaaattttc atttaattta tcttttattt
    63961 caactctcaa taaattccct ctaaactcta tatttgatat tataccttgg tagttttctt
    64021 ttgtcgattt ctctatttga acatattctg gtcttacagt taatatagaa tctccattat
    64081 caaaacagtt tgtatctcct ataaattgag ctgtaaatag gttttgagga ttttggtata
    64141 tttcttctgg agtccctatt tgcattatat ctcctccatt tagaatagct attttatctg
    64201 ccatagttat agcttcttct tggtcatgtg ttaccattat tgtcgttata ttaagttctt
    64261 tttgtaatct tttaatgtcc attctaagct tgtgtctaac ctttgcatct aatgcggaca
    64321 ttggttcatc taaaagtaaa aactttggtt caagagctaa tgctcttgct attgcaatcc
    64381 tctgttgttg cccacctgat aatgctttag gatatttatg agcttcatta gtcaatccaa
    64441 ctgtttcaag tacttcctta actttattat ctattttttc ttttgaaact tttctctctt
    64501 ttagtggaaa agctatattg ttataagcag tcatattcgg aaataatgca tatgattgaa
    64561 atactatacc aaaacctctc tttgatggct ctaaatttgt aatatcttta tcctggagaa
    64621 ttatagttcc actatttaca tcttcaagac ctgctattat tctaagtaat gtagttttac
    64681 cacatccact aggtccgagt aaacatagaa attccccttc ttcaatatcc aaactaatat
    64741 tatttaaaac ccttttttgg tcataacttt taaacacatt atttattttt aagtaactca
    64801 tatcttatct ctccttatat agttattttt ttattttaaa ttttatatcc tactttttct
    64861 tctaaaattc tttcatctaa attattaatt taaaccttac ttactttcag attttgaacc
    64921 gtattttgat tcccaagttt taagtactgt acttctgttt ttggcagcag agtttaaatc
    64981 aacttctttt ataagctgtt caaatggttg tttagaataa ccttttggaa ctggattata
    65041 tgtctttatg gaagtaactg ctacttcatg tgcatatcta tccatagctg aatcacttat
    65101 tgcccaatct aaaaatagct ttgcttcttt ttttatatta tcttttttaa ctaaggcatt
    65161 tgcttctaag tcccaacctg aaccttcctt tggaaataca acctctatag gttctccact
    65221 agataattgt tgtgtagctc tatatccaag tgtaatacct attggatact ctccagagcc
    65281 agctaacttc gcaggttttg aacctgagtg tgtatatgta gctatatttt tatgtaattt
    65341 atccatgtaa ttgtaagcat ctttttcacc catcatttga ataagccctg atactgtaag
    65401 ataccccgtt ccagatgatg ctggatttgg cattgttata agtcctttat attctggttt
    65461 tattaaatct tcataacttt ttggaatatc tatacctagt ttcttaagtt ccttataatt
    65521 aactactatt gctgtctctg ggacactcat tcctacccaa gatacatcat cttcagtatc
    65581 tttaaatttt ttatcaactt tatcataatt tttaggctta tatgcttcaa gtgcaccatc
    65641 tttttttagc tctatcatgt tcattgctga taatccccat ataatatctg cttgtggatt
    65701 atctttttct gctaatagtt ttgaagctat tacaccatga gaatccataa ctatctctac
    65761 atctatattg ggatactctt ctctaaaacc ttccatataa taagctatct gctcttcctc
    65821 tagtgctgca tatattgtaa gtttattatt tccttttcct tgagtagttt gtggtgttgt
    65881 tgatatgcaa cttgtcataa atgtaatcac tacaatgcac agacaagtaa atataaattc
    65941 tttcatatct tccccctttg tgttttttcc tttttttatt tgttttttat tgtttttgct
    66001 tatgtttata taatacacct aatttgttaa tataaagtta agtgtaaatt aacagttcgt
    66061 taatttttag aaatttttgt taaatatatt atttttagtt aaatacagtc tgtttttaaa
    66121 caatatatta atttttatag tatctacatt ttaatttaaa cataaaaaat aagtctaacc
    66181 tctataaagt agaatgttag acttattttt ataagtattt aattatacaa ccaaatcatt
    66241 ttttttcttt tcttcaagtg cttttttaag caccatatcc ttaaccttca taagtctagt
    66301 agtacttgct ctctcatttt cttcaagctt catagctata tacttaatag tctcaatgta
    66361 atttggtatc attacatttt caagagcatt aacacgtcta cgtgtctttt ctatctcttg
    66421 tgcaagaagc tgtgcacttt tttcactttc tgcaagtctt aaaagtggtt gcatagcatc
    66481 tgagaaagct tccatagcag aatctaattc acctgatgta aaagcaagac cataaggata
    66541 aatatcactt tgattgtttt cagttttaaa gtcaaacaca ggaacatcaa cactcattat
    66601 atttctcgta gaaacatcta ctgaaactga ttgctttggc atcataagtg ctgaacccag
    66661 atactcctga ctcataactg ctcttgcgat tataaagttt ttataagcag tatcaagagc
    66721 attttctgct tcttcacgca atcgcttatt ttctcttaca atctcaagaa attgtttcat
    66781 aagttcatca agtttatctt taagaagctt atgacctctt gtagcagttt taaggagttt
    66841 cttaagtcta gtcatttcca tacgtgttgg atttatattt aatctagcca cagatatcac
    66901 tccttaggca tatatttttc aaaatattca tcacggatac gtttaagttc actttttggt
    66961 aacatactaa gaagcttcca tccgatttct aatgtctgct caatagttct atcagttcta
    67021 aatccttgtg aaacatattc tttctcaaat tcatctgcaa acttagcata cattaaatca
    67081 atctcagaaa gtgcagattc accaagtata gccataagtt cttttgcatc cttacctctt
    67141 gaataagctg caaaaagctg gttcattgta tctgcatggt cttcacgagt cttaccttta
    67201 ccaatacctt tatcttttag acgagaaagt gatggtaaaa catctatagg aggctgtata
    67261 tcttttttat aaagttcacg gctaagtata atttgccctt ctgtaatgta tcctgtaagg
    67321 tcaggaattg gatgtgtctt atcatcctca ggcattgtaa gtattggaat catagttata
    67381 gacccttcat gccctttcat ttttcctgct ctttcataca tagtagcaag gtcagtataa
    67441 agatatcctg gatatccacg acgtcctgga acttcttttt tagctgctga aacttcacgc
    67501 aatgcctctg catagtttgt aatatccgtt attataacaa gtacatgcat atcttgctca
    67561 aaagcaaggt attctgctgc tgtaagtgcc attctaggtg tagatacacg ctctacagct
    67621 gggtcatttg caaggtttac aaacactaca gaacggtcga ttgcaccagt tgctttaaaa
    67681 tcgcttataa aaaattcagc atcttcaaaa gttataccaa ctgcagcaaa tacaacggcg
    67741 aacttagaat cagttccacg tacttttgcc tgtcttgcaa tctgaactgc aagattggca
    67801 tgtggcaaac cagaccctga gaatatagga agtttttgcc ctctaaccaa tgtattaagt
    67861 ccatctatag cagagactcc agtttgtata aattcggccg gataatcacg tgctgctgga
    67921 tttattggag ctccatttat atcaagtctt ttatctggta taatttctgg acctccatca
    67981 ataggtctac ccattccact aaaaacacgg cctaatatat ctggtgaaac tccaaagtca
    68041 agactctttc ctaaaaaacg aactttactt tcagcaaggt ttatacctgt tgagctttcg
    68101 aaaagctgaa caagtgcagt atctccattt acctctagaa ctttgcaacg gcgaatttct
    68161 ccatttgaaa gttcaatttc tccaagttca tcaaatttta caccttctac gccgtttatt
    68221 aacataagag gaccggctac ctcttgtatt gacttatatt cctttatcat agttcttcag
    68281 cccccctctt tttaataagg tctgcaagct cgttgtctat ttcatcttca attgaatcat
    68341 aagctgcatc tatatcgcct tcttctacat acttagcacg accaatcttt tcaagaactg
    68401 aaagcttgat aatatcgttt atagtaacat tttgcttgat agcatcttgt gctgacttat
    68461 agaattttaa tataagtccc atcattctat attgtttatg aagtgatgta taagtatcaa
    68521 cttcatggaa agagttttga tgaaggaagt cttctcttat agaacgagta acctctagta
    68581 tcaatctatc tccatctgaa agtgaatcaa ccccaaccaa ttgaactatt tcttgaagtt
    68641 cagattcaac ttgtaaaagt ttcatagctt gagctctttg agctgagaaa ttatcattta
    68701 catttttatc tgcccataca tcaacttttt cctgatagag tgaataacta gtcaaccagt
    68761 taattgctgg gaaatgacgt ttatatgcta aagatgcatc aagaccccag aatactttta
    68821 ctatacgaag cgttgcttgg ctgacaggtt ctgatgtatc accaccagga ggagaaactg
    68881 caccaattgc tgtaagtgtt ccttctcttt catccatacc tagacaattt acctttcctg
    68941 ctctctcata gaattgagca agacgtgaac ctaagtatgc aggataacct tcttcaccag
    69001 gcatctcctc taaacgacca ctcatctctc taagagcctc agcccatctt gatgtagagt
    69061 ctgccataag tgcaacacta tatcccatat ctctaaaata ttcagctatt gtaataccag
    69121 tgtatataga agcttcacgt gcagcaactg gcatatctga tgtatttgct ataagcacag
    69181 ttctttgcat aagtgactcg cctgttcttg ggtcttttaa ttcaggaaat tcaagaagaa
    69241 catctgtcat ttcatttcca cgctcgccac agcctatata tacaactata tctgcatctg
    69301 cccatttagc aagctgatgc tgtgtaacag tttttccact tccaaaaggt cccggtatag
    69361 ctgctacccc accttttgtg attgggaaaa atgtatctat aactctttga cctgtaacaa
    69421 gaagtgaatc tggtgttttc ttttctctat atggtctttc ttttctaact ggccattttt
    69481 gcatcatagt tacaggtata tcattacctt tttcatctgt aataacacaa actgtatctt
    69541 caacagtaaa ttcaccagaa tatatttctt ttatagtacc cttaactcca taaggaacca
    69601 taattttaca ttctactact gctgtttctt gaacgccacc aattatatct cctgctacaa
    69661 ccttatcacc aacagatttt ttaggtttaa attcccactt agttgttcta tcaagtgaag
    69721 atacttcaac acctttagtt atattagtac ctgaaatatc atacattttt tcaagtggac
    69781 gttgaatacc atcataaata gttgaaataa gacctggtcc aagttcaaca ctcataggca
    69841 ttccaagaga aactacttct tcccctggtc ctagaccgga agtttcctca taaacctgta
    69901 tagaagcttt atctccatgc atttctataa tctcgcctat aagatgttta tctgaaactc
    69961 ttacgacgtc aaacatattc gcatctctca tgccctccgc tacaacaagc ggtcctgaca
    70021 cctttacaat tgtgcctgtt ttcatattct ctcacctgca atcatatact ttatcaaaat
    70081 ttaaatattc cctcctatat tttattagca catatcttta gcaccaataa aatttgagat
    70141 tgtcttttat tcaactttca tctattcttt aaataatata tctgcaccta tagcacgttt
    70201 actagattct cttacttcat tcatacctaa tcccatactt cctccaatac ctggaataac
    70261 tataatggca ggaagttggt aatctttgta ttttgctatt gattcttttg caagcaatga
    70321 tgcctgttct gtaatataaa ttatcgcata ttcatcttca accaacttat gtatactttt
    70381 tttaatttcg tcactatcat aggctgggaa gatatctatt ccaagagcta aaaatcccat
    70441 gatgctatct ttatctccaa ctactcctac cttatacata agcatccctt agcctttctt
    70501 ttatagtatc tgcgtctata ttattaagct tactagtcaa aataattcta attgttttta
    70561 tctctgattc tttagcatat aaatatgcaa ttagtggttc taatgtaaga ggcttaaatt
    70621 ttgctcctct aacatattcc ataagatagt catcacaaag tttttcaaag acagtaaaac
    70681 cactatccat gccattttta cagacatcag agtaagaagt agatttaaaa catgatgctg
    70741 gagtatctga ggaaaaagct tctaagaatt tttccttatc aagtgagcca cctgaaacaa
    70801 acacattcat aaacatatca aaatctttct tcatattttt gactcttata aaactcttta
    70861 gatttgttaa atcgcaaact ttcataacat aatctattac aaatttgttt tggctttctt
    70921 tagcagtttc tttcatactg gtaaaggttg ctttatctag aacaatatca accatctggc
    70981 cattttgtgt cttattataa acatcaaatg cctctaatat agctgatgac attatcttag
    71041 gtaaatcact aaaactacga tttgctaaag attctctaag cttaataaga ggaattgtac
    71101 ctccatcaat taaatatttc tcaccatcta caccagaaat ttcttcttta atcagcactt
    71161 ttaaattgtg atagtcattt ttataaagaa atacatcaac aaatttttct tcaggagcta
    71221 gacttttaag aatttcatat gtctttgata attcttgagt caaaatattc tcaaaattat
    71281 gtatattatt atttgatgta tcagcataac ctgcctcagc tataattctt aaagagtctt
    71341 cagggctttt ggcttctgcc atttgaataa acatttgtct gttaagaagc tgtttttcaa
    71401 gcactcttat tcgtgcaacg gcatagggat aagttttttc ttctgccatt ttttaacccc
    71461 tccttaatta aacaaaattt ctgctgcaat ttgttcaata tattcatgct ctactgcaat
    71521 tatggcttca aatgaataat tgtactcaat gtcacctttt ttaactatga aacctccagt
    71581 aatatctcta gtttcatcag acactttaat gccttttttt gatagcacat cttttaatgt
    71641 ttttttatct tttttagata atactatctc tgaatcatct gtacaatttg atttttcaat
    71701 catgtttagt ataatctctt catattcatt atctttaaga tttaaaagtt tgtttttagc
    71761 ttctaaaatt acctcttcta aaatctcttg tttttttgat aatatttgct ttttagcctc
    71821 catataagct cctgatattt ccttagaagc cgctttttct gcttctgcct ctgcaagctt
    71881 tgtataggaa gccatttcct tttcagcttt ttcattagct gaatttactt ttaaatctgc
    71941 ttcactttta gctttatcca atatttcttg tgcttcttgt ttggcatcag ctataattct
    72001 gtcaatcatt ttttgttcat tacccatagg agtgcttcct ccttttcatt ttttttactt
    72061 atgaattata atttataatt aaccaattgc aattccattg taagctaaga aagaaacaag
    72121 tagtcctaaa agagcatatg tttcaactat tgctgcaaat gttatagctt taccaagttc
    72181 ttcaggtctt tttgcaacta ttccaactcc tgctgctgct gctttacctt gtgctatacc
    72241 tgatactaaa ccaactaaac caattggaag tcctgccata agaagttgta aaccttgagc
    72301 tgatgttggt attgcatctc caccaataat ccctgctttt gataaaataa ggaaagctat
    72361 gataaatcca tacagacctt gtgtaccagg aagaagttgt aaaactagaa gttgaccgaa
    72421 tttactaggg tcttctgtta caacacctgc tgcggcttga cctgctattg aagtaccttt
    72481 agcagaaccc atacctgcaa ataatgctgc tatagcagct cctgatattg ccaaaaattg
    72541 accatttcct aacgcgttta aaaattccat atttacatct cctttttatt aatgcttgta
    72601 tattttgttt tatacttaaa cggaacaaaa ggaactcctc cgccttcata aaacttattg
    72661 aaaaattcta catactgtaa cctacttgta tgaacatatg cacctagtgc atttataaga
    72721 aggtttattg tgtgtcctac aacaccgatt acaactgcaa gtatcggacc agctatagcc
    72781 cctaaaaggt tgataacttg tgctataact cctgttgtta aacaaagcgc cataattctt
    72841 gtataagata atatatcagc aaaataactt gttatgccat agagacttga aaatccttta
    72901 aaaagcttaa caggaatacc tttaaagctt cttccttgag taagtacaag acctatagca
    72961 cctataattg ctaaatattt tcctacttct gaaaatacac ctatgtcccc tgcaacaaaa
    73021 ggtattataa gtagacatac acctgttata cacaaatacc aaaaacctat gtcaaagatt
    73081 gcatctatta cctttccact tcttattaat gtatatgctt ttattcccaa acctacatat
    73141 atatggataa taccgaacag taacgacatt cccataagtg tcataacatc ctctaaagga
    73201 ttaattaatg cttttatagg aattaaatcc cccaaaatac ccccgaatat aagaccccat
    73261 acagtagttg aaactccaca gataccaata agtttaatta aatttccttc acctttttgt
    73321 atctttaatt tatatacaac aaatccacag actactgcaa ttattaaccc atatgcggcg
    73381 tcacttagca tcattccaaa gaatacaaca aagaagaaag ttaaaattgt atttgggtca
    73441 atatcttttg tacttggata gctgtacatg ttagttacac tttcaaaagg tgttactaat
    73501 ttattgtttt caagcagaat tgggaagcct tcttctttac ttccttcttc agtctgaaca
    73561 caacaatcaa acttttctgt aatttcttta attaattcat ctgccctttt gcttggtaac
    73621 caaccattaa gacagaatgt tgtttttgtt ttgacaagtc tctctataat ctttttttgg
    73681 tctctttcta tagtgtaaaa atcatatagg ttttcaagca tgtgtatact atctgcatgt
    73741 cttttaattt cctctgtttt gtccttagaa acgttttcct gcctaattat catttcattg
    73801 tatttcttga tagcttgtaa cggtgtacct tcttcatttg gtaatgaaac cactgaaaaa
    73861 ttaaattctt ttaaaacttc taaaacatca tcaaaagttt cttttaaagt aattaaataa
    73921 acatagttca ttaacttgtc agaattgaca atcccaataa cactttctgg tatttcatct
    73981 tctaatttta ctcttaaagc atcaatattt gcgcttatgg gcacagttcc aagtatagtt
    74041 tttgtatact tagtttccat attttcaaga ggaatatcaa agttcaccca tggttctaac
    74101 atacttttat tgttgttaag taagtttatg ttagacctta ttgtacctat ctccttgtgc
    74161 aaattgttta actccagagc ttcagcataa acttgccctt ctttttcact atcaattttg
    74221 ttaaactctc tttttggtgc aagtagggat tttttttgtt tcactagtga agaaacaata
    74281 ttaattgctt ggtttacatg agacattttc tgctctagca ttataacttc agattcttca
    74341 ctatctttta caagataatt ttttaattcc tcctcctcag taagaaaggc actatcatca
    74401 atctgaacaa acccacggtt cataagtagc tttaaaatct ggcttttttg agcttctaag
    74461 ccaacaatag atattttgtt catattaact attgccatat tatctcacta cctttccaat
    74521 aaccgcttca atagccttac tttttctttc ttcagcagtt ttttcaattt tcagacattc
    74581 acttttagca ttagctaaga ttttatcaac ctctgctcta ctgtcggtga ctgccttctc
    74641 aataagagtt tcttccataa gctttgcttg ttttcttaca tcagcaaata tgctttcaca
    74701 tttgtttaca gcatcagctc tgatagactc tgcatcagta acagctttta ctttgatact
    74761 gtctgctgtc tgctctgcct caacaatgct ttttattatt tcaaaagcca tccaaatcac
    74821 ctctcttacc tttttactat gtatataacc aattagattt ttttattcta attagattac
    74881 tacctcattg ttaaagtata aacagcattt ttatataata attaatattt ttcaacgttt
    74941 atttcttaat aaaacatatt ttagaatagt acttgcctag atttacatcc ttttttgact
    75001 tacttttaga ctatgacatg agtatggttt ttaaatacca ttattttcaa taattataat
    75061 ttaaagcgat atagtttgtc aatagcgtta ttttgtttta aaattaacgc tatgtcgaca
    75121 ttttaaattt ttattttatt ttttttataa ttttaattta atttattaca tataaaagtt
    75181 ttttatattc tttttcaacc tctaaccctt gaagtttatt gttttttttg aatttttaga
    75241 aatatctcgc actattttat ctaactttta taaatcatca agctatatcg atttttgtca
    75301 ccttattttc aatctaaatt ttttatatat agttagaaat aaatcaatat ttttaaagat
    75361 tgataaaact tacacttagt tctaatagtt ttattttaag gcaatgtatt aatcttaagt
    75421 agataatatc attagttact ctatatattc gacaacatta taaaaaaatc ctcgtaccaa
    75481 tcactccaat cttcaatagg atatgctgct cctccattta cacttttcag taggtttgat
    75541 gtatattctt ctcccatgga aaaaagttcc cctactgtta tatcataacc tctagatgta
    75601 acaaccttac aaaatgaatc cataacatca cgttgttctc ttgtttttat aagttccttt
    75661 ctaaattcat catcattctt agcttcttct aaaattttag ttaatttttc attcattatg
    75721 tatttctcct tttaagtagt ctttctgtaa acttcaataa gctttatata aaaaggaagc
    75781 catcctaaat aaactaagat gacttcgctt aactgttagc aacacattta ctagtataaa
    75841 ataattggtg tacctggttc tatattttca tatattttct ttgccttaga aaaaggtgta
    75901 tttacacatc catgtgaacc tgaagactta tatatacctc caccaaaaga atttctccaa
    75961 gtagcatcat gaatgcctat gttcccatta aatggaagcc aataacttac aggtgaactg
    76021 taaccttgac cagttaatga aacatttcta gccttataat taagaggata tatacctgat
    76081 ggtgtagcaa atcctctagc taaatcgcct gttacaacat ctgttgatac aagcatttct
    76141 ccatttttaa agaaccacat atgttggcca gaaagactaa tctctacata tgtatttcca
    76201 atatcatctt tattacgaga tacagctttt tgtatgtaaa taggttctct tgtaacattt
    76261 ttaccagctt ttacaacatc aactaatgct tcagcttctt tctttttatc tatcaaccaa
    76321 ccataaattc cacctgaaat tgtaatatct ttacctgtgg cagttttaaa tggtcttgag
    76381 tcaccaaaag tactgtattt tttacttaaa cttcttgtat attctaccat agcatcatta
    76441 tcaaaagtta tgtcataatt cttttctgag tctactttta accatttatt aatttcagaa
    76501 ccatctaaag tttccttacg gtcactaaaa tcatatgtaa cgactacacc aacatactta
    76561 tctaatgtct taatagcttg tttcaacttt tctgaatcct ttgtgttgtt tggtgcttca
    76621 taaactttac tttcatccag agaaatagaa gtattcccag aattaattga gttttgtact
    76681 aacttataaa aatcatcttt tttcactttg tttccaagta cctctggtac tataacataa
    76741 gcgtttttag tgctatcata cttaggataa gcactcttag gttctacaac atttttacta
    76801 tcaaaacaag ataaagcatt aaaccttttt tctagtaaat ctttattata tgaaagagtt
    76861 atcatattat tatactcttt agatttaaat attccaccaa tccatccaat agcgctttga
    76921 ctatctttta tcttttgaac tttatcatct ggtgtaaatt ttaaatcaat atcttttgct
    76981 tttatttgtt ctttcttatt gtttctttcc tctaagttta aagtatagga attagtacta
    77041 gatgttaaca aatcatttac ttgctcaact gtttttcctg aagcctttac gccattaata
    77101 gtcgttccaa agtaaaaatg atttctaaaa aagattgcca ttcctatata agctacaaac
    77161 aaaacaccta caactatagc tatcttaaat tttagatttt tttgtccact ttcttgtttt
    77221 acctcttttc catcaatcat aattaaatcc ttccttacat tgtaattacc tatgtacttt
    77281 attggttttt aaacaaaacc atgtatgcct tattttatat acccaaatta ctgtatcatt
    77341 gtttatattt ttaaatatat agttatttcc ataaaaccat tttatctttt agacaaaatg
    77401 actattataa atcacccctt tcaaaatccc ttaaatacaa tctctgctat attaatatat
    77461 taccatactt ttaataatcg tgggttatct atctgttttt gtaacactaa actactcttt
    77521 taaaaaagaa actaatttta tgttagtttc tttatcttaa cttattttta tattgaattt
    77581 tagcttaaca taacgttgtt atatagattc tatttaatta ttttagtttc tatatctttt
    77641 ccatcagcat attctttaag taactcctta gcatatccaa aatattcttc aatatcagat
    77701 tcttgactaa aagaaaatat acaaattaat atttcatttg catcttctgt tatcattgct
    77761 ctttcagaat cactagttgg actcccaaat ttacccactg aatcagacaa tataggaaga
    77821 ttttctatat ttattaattc tttcccaata cccttatact gttctccttc atctcctaca
    77881 gtaaaacata ctggtgaatg taatttgctt acattatatg tacctactgg atataatgat
    77941 tttattgata ttaaattgtt tatttctact atattattta ttgtataaag acccttccct
    78001 tgaataattc ttctaaccaa tgcttctgaa gatgttctat atctacttgg attttttcca
    78061 agctctttat aagcatttct tgcatcttta attttatcta gtttcgtaat gtcttcaact
    78121 tttagacttt gatttatagt atcacaaaac tcatttattt cattaattaa tttttctgag
    78181 cttttattta ctgctacttt tgcttgaatg caacccaact tagcattagg ccatctttcc
    78241 ttaagtttgt catcaatact cacatctatc atacttaaac aactcctata cactaaattt
    78301 ttattaaagt ttttatcatc tatacattat agtactattc ttttgttaat aacatgttta
    78361 ttagcaaaat aaatttattt ttaatataat ttttataaaa tacaattatt ttttgcttta
    78421 tattaaacaa tacattgata aaataaaaaa acactaatta tttagcagtg atttattaaa
    78481 atcaaacatt cataatagtg ctttatataa aaattaaatt ttgttttaaa gtaaatctaa
    78541 aaaattctta gctggcattg gtcgtgcaaa ataaaatcct tgaactaaat cacatccaaa
    78601 ttgtttcatt aactcagctt gttctttact ctcaacacct tctataatta caactaaatc
    78661 tagtgatttt gctagagaca ctattgattt tgctatattg cgacttctct catcatgttc
    78721 aataccatta agaaaagact tatctagttt caatatatca attggcatat ctcttaaaca
    78781 actaatagaa gaatatcctg taccaaagtc atccatagaa atagaaaatc catacttcct
    78841 caactcattt aaaacattct ttaaaatatt taactcatta atagccacag tttctgttat
    78901 ctctatttca attaaatctg aacttagatt atacatttgt attgttttat tgataaattt
    78961 tacaatatct ggttgataca actcaactct agataaattt attgaaactg gaactatctt
    79021 tttaccttgc tttttccatt cagataaatc attgcaaacc ctttcaaata caaatctccc
    79081 aatttttaaa atcaacttac ttttctctgc tattggaata aatactgcgg gacttataaa
    79141 accatgttct ggatgattcc atcttattag tgcttcactc cctatcattt ctccagttac
    79201 aagtgaaaac ttaggttgat aatacacttc aaattgattt tttaccaatg ctatttttat
    79261 atcatctaaa atcattgatt cttcactaag cttattccta acatcttcat tataaatagc
    79321 ataatttata tttttacctt tagcaacaga cctagccata tttgctttat ttacagcctt
    79381 ttggatatct acttcacctt cttcaacaaa ataaataccc acacacagag aaatttcaaa
    79441 tactatactc aaattacttt caatattatt tcgtatacta tcaatttttc ttatacgttt
    79501 attttttcca tttttataat cacagaaaat tgcaaaataa tcacttgaaa gtcgtgcata
    79561 tacttcacct tctgttaatt cttcttttaa agcttttgct atcgtaatta ataaattgtc
    79621 accaaattca tatccaaaag tatcattaat catcttaaag ttattaatat caaaatatac
    79681 tataatataa tttaaagatg gtttatctaa aagatactta ctacactctc tataaaattt
    79741 attttgattt cctatatggg taactttatc ttcataagcc aaacttaata tttctttttc
    79801 attggatttt tttatataaa ttatataaaa aataattgca ataaatatta atataataaa
    79861 taacactgca tatatagctc tgttgattat ttgttctgaa ttactaaata caacagtttc
    79921 tggaattgaa aaaatcaaat tccaatcttt tatataatta ttttcactat tcccattatc
    79981 catagtagca tatcctaaat atcttctttc ttccaacata tttaatacag ttgcacctgt
    80041 tttattttct tgcaattctt tttttaatct atttatttct cgaatatcat tatcctgttt
    80101 taacaattta taaatatttt ttgataggct atcctcttgc ggatgaagga taattgtacc
    80161 atcatttctt acaacataag atatactatt attttcataa aaagatacat taataagttt
    80221 catcagagta ttgatattgt aagtacaata taaaactcca actactttat cattatttaa
    80281 taatggtact gaaatagtaa tcttctttat agacttattt acttcatcaa catatggact
    80341 tgaaacatac ttcttacctt taattgagtt tttgaaaaat tctctatctt tcactgaaaa
    80401 cttatcacct ttggtatttt cagcattacc atttatatca actattgcca tagtgtaaaa
    80461 tttttgattt tccatttcat ctaaaagatt tttcattttt tcctcattag gtatatcttg
    80521 atttaaagca taatagttag aaaaaatatt taaaacatct aaatcttttt caatttgtct
    80581 ttgtgctagt tgagagcctt gtactgcaac ttcttttata tgtatttttg cctctgacat
    80641 aagaagatgt tttgtatctt ctatatagat ataccccatt gtcaaaaata atgatgttaa
    80701 aaaaagaatt gtaattaatg taaaactttt atttctccct gtcattcgac tcctccccta
    80761 attagtcaat acttcatata gataatatat cctttttata ccgattcatc atttatattg
    80821 tatataacta ttcttaaatg ttacacataa aatcaaccta ataaccataa aaacattctt
    80881 ttattatcat aataacacta tttagttgaa ttttaaatta aagaataaaa actatcaatt
    80941 tttctaaaca aaaaaactct tatacaataa aactttgttt tatgtataag agtttttatt
    81001 ttatctattt tatagtaaat ttatcttcca taatatgaat ttaaatacat atcttttatt
    81061 tcattcataa gtggatatct tggatttgct cctgtacatt ggtcatcaaa tgcttgaatc
    81121 accatttcat ctattgaatc cataaactta ggttcttcaa ctccaaactc ttttatagat
    81181 ttaggaatac caactttaag ttttaaatct tcaatagcta ccaataaact ttggaatttc
    81241 tcttcatcag aatttccctt taatcctaaa aatgaagcta tttcagcata tctttttaat
    81301 gcttctggat atttatattg agagaatgct cccattttct ttggtgcatc tgaagaatta
    81361 aatttcataa cttctgttat caaaagagca tttgcaacac catgtggtac atggtggaaa
    81421 gcacctaatt tatgagccat agagtgacaa acacccaaaa atgcatttgc aaaagccata
    81481 cctgccattg tagaagcatt tgccattttt tctctagctt ctgggtcttt tgcaccatta
    81541 tcatatgcac gtggaagata ttcaaatata ctcttaatgg cttgtaaagc taatccattt
    81601 gtataatcag ttgcaagcat agatacatat gcttctaatg catgagttaa tgcatctata
    81661 ccagaagcag atgttaagct ttttggcata ttcatcatca tatcagaatc aactatagcc
    81721 atatttggca tcagttcata atctgctaat ggatatttta cccctgtatc ttggtcagtt
    81781 ataacagcaa atggtgttac ttctgaacca gtacctgctg atgttggtat agctacaaaa
    81841 ttagcttttt cacccatttt agggaatgta tatacccttt ttcttatatc cataaatctc
    81901 atagctaggt cttggaaatc tacatctgga tgctcataca atgtccacat tatctttcct
    81961 gcatccattg cacttcctcc acctatagat attattacat ctggattaaa ttctctcata
    82021 gctttagcgc ctatcttagc acattccaaa gttgggtctg gttctacttc aaagaatgta
    82081 gtgtgcttaa tattcatttc atctaataaa tcagtaactg ctttagtata tccattattg
    82141 taaaggaatg tatctgttac aataaaagct ctcttcttat tcattacatc tttaagttct
    82201 tttaatgcta cccctaaaca accttttttg aaataaactt ttcctggtga tctaaaccaa
    82261 agcatatttt ctctcctctc agctactgtt ttaatattaa gtaaatgctt aactcctaca
    82321 ttttcagata ctgaatttcc accccaagac ccacatccta aagtaagaga aggagctagt
    82381 ttaaaattat ataagtcccc tataccacct tgagaagaag gagtattaat taaaattcta
    82441 caagttttca tggctgaagt aaacttatca agtttttctc tttgatttac atcatcaata
    82501 tataatgaag atgtatgccc aaatccacca tcttctacta atttttctgc ttttctaact
    82561 gcattatcaa aatcactggc cttgtacatt gcaagtactg gtgaaagttt ctcatgagca
    82621 aaagcttctt ctatttcaac tgattctact tcacctatta aaaccttagt atctactggg
    82681 acttcaaagc ctgcaagttt tgctatagta caagctgttt gcccaactat tttagaattt
    82741 aatcctccat ttactaaaat tatatttctt attttttctg tttcatcttt atctaataaa
    82801 taagcaccac gctctttaaa ttcttttttg acttcattgt atatattttc taatactata
    82861 accgattgtt cagaagcaca tatcatacca ttgtcaaaag tcttagatac aagaattgag
    82921 tttacagcag tttttatatc tgcactctca tcaattattg ctggagtatt acctgcacca
    82981 actccaatag ctggttttcc agatgaatat gctgatttaa ccattccagg acctcctgta
    83041 gcaagggtca aatccacttc tttcataaca gttgtagtta attctaaaga tggctcatct
    83101 atccatccta ttatgccttc aggagctcca gctaaaacag cagcctcaag aacaactttt
    83161 gcagcctcta tagtagaatt ttttgctctt ggatgcggag agaaaattat tccatttcta
    83221 gtttttaaag ctaaaagtgc tttaaagata gcagtagaag ttggattagt tgtaggtaca
    83281 actgctgcaa taacacctat tggctcagca attttagtca taccaaatgc ttcgtctttc
    83341 tctataacac cacaagtttt agtttcttta tatgcattat atatatactc tgaggcataa
    83401 tgattcttta taaccttatc ttcagcaatt cccataccag tttccttttg tgccattata
    83461 gctagaggaa ctctttgctt attagctgcc aaagatgctg ctaaaaaaat tttatctacc
    83521 tgctcttgag tatatgtagc aaatattttt tgagcttctc tgatttttgc tagtttttta
    83581 actaagcttt caacgttatt tacagtatct aaaccaactg acataacttc attttctttt
    83641 ttattttcta ttattacttg ttctttatga gccattttaa caacctcctg agatagtttt
    83701 ttatttatta tgttaattta ttaacattat agcatttact ttttctattt tcaagttatt
    83761 tttttaacat tttatttttt atctaatata acatcatttc tactaataat atctagcttt
    83821 acaaatactt aatttaacta gatatcactt tattttttac gcaaatcact aataaaatca
    83881 tctaaaaact taaggataac gttatttttt taacgtttat atttttgtat tttttgcaaa
    83941 taaaacttta taaaaagaat ttttaatatg atattctatc aagtttaaaa ataaaaatac
    84001 ttgaaaatga aaataataac ttgattaaca agttaaagta aatatagtta aatgtacaaa
    84061 catttacaac atatagtata attaaaaaaa tatatattca tgatttttat atactatgaa
    84121 ataaaatata tttaatatta tatagataaa tttgaagttt ataagaagga ggataagcat
    84181 gaaaaaatta aaaacaatta gcattttttc tttgattata agtgtaattt taacgattgg
    84241 aggtattgga atagtaactt attatgtaga taatttgttt attagaggac tatcagtatt
    84301 tgttttaatt atgtcctctt cttttgtatc aacaacagtt agattgatat ttgaagagtc
    84361 aaaacgatat aaattctaat ttaaaaattg gattaagtaa ataattttaa tataccaaaa
    84421 attacggaga ttagctcaaa atagactttt tagttcatga tgcatttttt tgtatgaaat
    84481 taaatatatt ttcatcattt caacaatgaa aaagaggctt ctctctattt tgagacagcc
    84541 tctttgctag tattgtatct aatacataat attataagaa ccaattctat tgatgtggac
    84601 tttttataac aggctgtagc tgtttgttct ctagagcaag ttctatagtt ggaattatta
    84661 gctcagtatg tgcaatcata gaattaggct ttgctttgca attatcttga ccaaaaggta
    84721 caaaatatat atttttagaa ttaaggagaa taccaatatt tttgaaatta aagcttagag
    84781 catcattcgt tgatattgat attactagtg gtttatcatt acgaagatga ccttttgctg
    84841 ccattaatac tggtgaatct gtaataccat ttgctaattt tgcagcagta tttccagtac
    84901 aaggagctat tattataata tcagcaatcc ctttaggtcc aaatggttct gcctcttcaa
    84961 tcgtaactat aggtttattt cctgtaagtt catatgcttt tttcataaac tcttcagaat
    85021 ttccaaatct acaatcgata ttttgtgata catctgaaaa tatagtgtgt acattagctc
    85081 cttctttaac caaattctct aactctataa atattttatc ataagtacaa aacgaaccag
    85141 taaatcctac tccaattgta agtccttcaa gtctcatttc taatcccttc tttcatttat
    85201 aatattttct atagcgttaa caagaatctc accagatgtc tttggtgaat atttaccagg
    85261 aagcccaagg caaagagtcg cattaatccc tacttcttta acaacagaat aatctactcc
    85321 tccaggagaa gaagctatat ctataatagt tacttcttgt gatacttttt ctaatctttc
    85381 tttcgttaaa atacactctg gtatggtgtt aaaaatataa tcaaattgta aaagtttttc
    85441 atcaagttga cttaaagaaa tactggaata tccaaatgca ttagccgtac ttcttgcatc
    85501 attatttctt gcaccaacgc atacatttgc atccaaagcg tataattttt ttgcaagtat
    85561 ttgtgcacat cttccataac ctaatactaa acagttactt tgatgtatat tgattatact
    85621 tcttttaata gcttctgcta tagccccttc agctgtagca actgcattta aaatagcaac
    85681 atcattcatt ttcataaaat cataaatctg aatagagtgt tgctcgcaaa atttacaaac
    85741 tttagttggt atgttacctc caaataatat ttgattagga gataaattaa ttagcaagtt
    85801 atcaatagta gcatcaagac aatcatccgt attttcaata ttaacttgat tctttgtaaa
    85861 tggaattgga cataaaataa tggaactttt ggatagtgct tcagctagtg aagttgattt
    85921 tccaacgatt ccatttataa tttcatttga tatcccataa gtgactacag aatacccttt
    85981 attaattagt ttttttacca tgtacacttg tcgcaggtct cccccaataa cagttatatc
    86041 gtattgattt gacatattgt aagcctcctt tactatatac aatatgtttt tatcaataca
    86101 ttggttcact aaaattacta aatattatac ttataacatt tttaataatg ctaatctatc
    86161 tatcttttca gaagaggtat atggaaatga atttaaaaag ataattttct ttgggatttc
    86221 atttttcatt agattatctt tcattttaat caacaaatct ttcttcgtaa ttttgtctat
    86281 agttattaca aataatacaa tttgatttcc tcttatagtg tctgagtacg gcaatacaat
    86341 tgcatcttca atttgaggaa tttttttaac ttcattttca atcttagcag aactaacttt
    86401 aaatcctcca atatttacaa tgtcatcact tcttccttca aatattaagt atccatcatt
    86461 atcataatat ccaatatcat tgacagaata aggtttggtt gcattatata ctgcatattc
    86521 tgtattcaca aaaatttttc ctcctctaat atatatatct attcctggaa atggtctgcc
    86581 tacacttaga ggtttttcaa ttagttcatc atagcataaa tatgtaatat aatttaattc
    86641 acttgcccca tagtataaaa taatttcaga ctttggcata tattttttta gatttcttgc
    86701 agtatattca aataataatt gagaccctgt aaaaatactt actactttga gtactggttc
    86761 ttttaagtgt ttaaccaaaa gttgaagttt tgtaggtata aggtatatgt tagttacatt
    86821 atattgtttt attgtcctta tccatgattt acaattaaga cctgaactta ttacaatact
    86881 acctccttca tataatactg acattataga atttagattc cctgtaaaac taagtgttcc
    86941 attaacaaac aagattgatt ccccagagat attaaaaata ccattttgta taggaaaaaa
    87001 tccagcccaa ctctcatatg ttctatataa tacctttgga acacttgtag aacctgaaga
    87061 taaagctccc atacaaatac ttttatctaa ataatttata aggttcttat attgatacat
    87121 atatagatta aatttaggat taaaaataga aaaattaact ttttttgcta cttcattatt
    87181 gttatcatca tataaatcaa taacgtccat agattcatca gatataatga ttgaaatatt
    87241 attttttaat aaaatatcat ctaatacttt tttagaaaga ttataatgac aaataatagg
    87301 aatatttttt gaataattaa tagcaaaaaa actaatcaac tgaaacatta tatttttaga
    87361 atatattaaa attgagatat tttcacctaa agaaatttgt tttcctagtt gctcactata
    87421 acttaatata ttttcataag tatatttttc tccatctata attaaaaaat ttttattttt
    87481 atgcctctct ttttttattc ttaaaagttc ataatagttc ataatctaca ccctttcaag
    87541 cagtaaagct gaacctagac caccagctgc agctatagag caaattccat atctaccctt
    87601 agttttttct aatgctttta aaagatgtaa tgtaataatt gcacctgaag caccatatgg
    87661 atgtccatac gctaaagctc caccaaatat attatatctc tctattaact ctggatactt
    87721 tctttgaaac aacacatcta taactgcaaa tgcttcatta aattcaacag cagatacatc
    87781 taaataatta aggctttcta tctctaaaag tttatccatt gcttgtatcg ctgatgttgg
    87841 acttaaggtt gcatctgttc ctattgtgca tgtattaata atttttgttt taggcttctt
    87901 ttttacatgt tctaaatact tcttagaaca tattataata aatgaagctc catcattaat
    87961 aagacatgaa tttgctgcat ttgtaatagt ttcttttcct aaaattggtg gcatcctatc
    88021 taataacctt tgactcatct tatcacgtat accttcatca taggtactat tatttatagg
    88081 agatataata tcctcaagta ttttttcttc tcttgcttct tttgctcttt tatgactttc
    88141 ctttacccaa aaatccaagt ctgctctctc aatttgatat aactctgcta ctctttccgc
    88201 cccttcgagc atactatttt gactattatc atcaggagaa aattgagcaa ctgtataatt
    88261 tggattattt gtattatatc gcttatcatt cttatgatat gtgcgcattg gttgtagaga
    88321 actactttca aaaccacctg caataattaa attacactga ccagatttaa cctttgaaaa
    88381 agctatgtct atactcatca tagcagaagc acactgcata tccacagtaa aagcaggtac
    88441 ttcatttgac actcctgctg ttaaagtcat taatctggct atattccctc ctgtcccaac
    88501 tgcatttcca catataatct catcaatttt gtcaatttca tactttttaa ttaaatcttt
    88561 taaaacactt gctcctagta attcaggttg aacaaattga aaaattccat tttttagacc
    88621 tatatgactt ctcaatcctc ctaatataaa aacttccttc atacattaca cccttcctta
    88681 tattatagat ttatcataga tttcttctga gtacattgtt cagtttagtg cctaaaaaag
    88741 atgcaataac cgactttatt gtatctccaa ttaaaaatgg tactactgct gcaaaaagtg
    88801 ctgcttctac tgtcatttga ttaaaatagc acataaatac tgttcccata aaatatataa
    88861 taggcattcc aacaaaaatt gttattagta tatatctctt aatatcatta tttcgtcctt
    88921 ttaataaact aataattagt gctgcaaaca aaaacccaaa ataaaaacca cctgttgggc
    88981 ttaacaactt tccaatacca gatgtacctc caccaaatac tggaatccca attaaaccta
    89041 tcattatata tacaccaact gtactaaatg cttgtcttgg tgttaaaatc aaagctatca
    89101 aatttatcat tattgtttgt gctgttactc ctgctggagt aaatggcaat ggtatatata
    89161 tgtaagatga tatacacaat aatgctacac atattgacat tttagttaaa tcttgaatat
    89221 ttactttagt atttttcatt tttataattc ccttcatatg tcttatttca tttagtttat
    89281 atgtacatat acaaagcctc tattaaagct ttgttttagt ataaaataaa gacgtttttt
    89341 tgtcaaccat tacaagtatt taggtttacg tttaatttat aagtaaactt tatactgtta
    89401 ctttatattt taatagtcat ttataaaact ttgcttaaaa acagctctat ttagactata
    89461 cttgtaaatt ataatatgat atatttttat ataagatttt attttatata aaaaatagta
    89521 acaaatagtt tatacacaag atatttaaaa ggaagtgatg atatgaaagt taatgaaaat
    89581 aatataaata atatagatga agagttagat gaacttagta ggaaagttta cttagagtca
    89641 ccagattttt ggataagtat ttctgacaaa ataatagata aagtatttga tgaaatgtta
    89701 ttattttttg cagttaaata taactatttc aatatagtat gctttgctat tgaaaacaat
    89761 tatctggatt taaacatgcc ttcaaaaaac aaaaaataca ctaatataat ggagcatttg
    89821 ttagatacat caaaacagaa tgaagataaa aaaatttata attatcttct aagcttaaat
    89881 aaaggtaata acctagatga aagaccaatt ttagatgaat taaactgtaa tattagtagt
    89941 gatacttttg aaaaaaaaga tatatatctt ccaaagtact tatgtccaag ttgtaattct
    90001 aatatatttg atacaggtta taaagtatca aatgacataa catataaatt ttcttctaaa
    90061 gaagctgaac ctattgaaat gtctagtgaa gtttcttcta tcagatgttg taattgtgat
    90121 gaattattag aagatattac acttaataaa ctatataacc tatgtaaaat tcaaaactgt
    90181 aataattgtg gttctaattt aactaaggta ggaattattg caaagaaaaa aatgaacttt
    90241 gatgagaata ctgaaaaatt taaagatgtc tcaacatctt actgttgtgg aaattgtgac
    90301 tctgaaataa acttatctca aagagaacat tttaagattt aaatatttat aggctaaagt
    90361 aataagatta cattattaga tactgtataa gttttttaaa tctgtaaaaa taaatacact
    90421 tataagaatt aaaattgcta tgaaactagt tcttgctgaa ctaatttcat ggcaattttc
    90481 tataatctaa taattattaa attttaacaa acctttatta gcattccata attattcaaa
    90541 attctttcaa ataccctata gtttataggt gaaagtatct ttaatattat atcaaactta
    90601 ttatctttaa atagtaaatt tgttaaatct gaaatacacc atacaatttt attttcctct
    90661 tttgtagcta tatcaattct gattaactta catctataat aaatatcttt atcttcatat
    90721 agtctatttt aaa
//
LOCUS       DAEQJM010000011        89748 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.011, whole genome shotgun sequence.
ACCESSION   DAEQJM010000011 DAEQJM010000000
VERSION     DAEQJM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 89748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89748
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.011"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            171..821
                     /locus_tag="KRQ43_000981"
     CDS             171..821
                     /locus_tag="KRQ43_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBH2741351.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(961..2337)
                     /locus_tag="KRQ43_000982"
     CDS             complement(961..2337)
                     /locus_tag="KRQ43_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2741352.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2353..4266)
                     /locus_tag="KRQ43_000983"
     CDS             complement(2353..4266)
                     /locus_tag="KRQ43_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH2741353.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4402..5034
                     /locus_tag="KRQ43_000984"
     CDS             4402..5034
                     /locus_tag="KRQ43_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBH2741354.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5173..5712
                     /locus_tag="KRQ43_000985"
     CDS             5173..5712
                     /locus_tag="KRQ43_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH2741355.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAARKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(5888..6058)
                     /locus_tag="KRQ43_000986"
     CDS             complement(5888..6058)
                     /locus_tag="KRQ43_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2741356.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            6343..7410
                     /locus_tag="KRQ43_000987"
     CDS             6343..7410
                     /locus_tag="KRQ43_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HBH2741357.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSIEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSSSRNNYQPKVL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            7580..9481
                     /gene="cooS"
                     /locus_tag="KRQ43_000988"
     CDS             7580..9481
                     /gene="cooS"
                     /locus_tag="KRQ43_000988"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH2741358.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            9474..9947
                     /locus_tag="KRQ43_000989"
     CDS             9474..9947
                     /locus_tag="KRQ43_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH2741359.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            9922..11148
                     /locus_tag="KRQ43_000990"
     CDS             9922..11148
                     /locus_tag="KRQ43_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH2741360.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDVCY
                     ADFFNIKENGEFCYSV"
     gene            complement(11287..12474)
                     /locus_tag="KRQ43_000991"
     CDS             complement(11287..12474)
                     /locus_tag="KRQ43_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH2741361.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKSFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            12747..13571
                     /locus_tag="KRQ43_000992"
     CDS             12747..13571
                     /locus_tag="KRQ43_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBH2741362.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            13700..14965
                     /gene="gluD"
                     /locus_tag="KRQ43_000993"
     CDS             13700..14965
                     /gene="gluD"
                     /locus_tag="KRQ43_000993"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HBH2741363.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            15158..15814
                     /locus_tag="KRQ43_000994"
     CDS             15158..15814
                     /locus_tag="KRQ43_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH2741364.1"
                     /translation="MYFLPPHDYKLEELDWIFGHELMYFKSKDLHLKYLVLFLKIVYW
                     FNPFIYIMEKYMDLDCELYCDERVLKNCTVQQKQEYALTIVNSMKRGINFSNKFVTGL
                     NKQSDIRKRVMNMFSEKHKNGILMALIISLFSSITFFKFDSTSLIEENDFLERSRYAF
                     EGRQEDMFVTIDSTYADAPIKLRKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK
                     "
     gene            16145..17278
                     /locus_tag="KRQ43_000995"
     CDS             16145..17278
                     /locus_tag="KRQ43_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH2741365.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFEDLRTVSSIRFSVIGF
                     TYADAPKNMREEYKINCESLGLIPKDSDKIEVGVEYYDSLLND"
     gene            18205..19227
                     /locus_tag="KRQ43_000996"
     CDS             18205..19227
                     /locus_tag="KRQ43_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH2741366.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            19523..20443
                     /gene="pyrB"
                     /locus_tag="KRQ43_000997"
     CDS             19523..20443
                     /gene="pyrB"
                     /locus_tag="KRQ43_000997"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBH2741367.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            20482..21174
                     /locus_tag="KRQ43_000998"
     CDS             20482..21174
                     /locus_tag="KRQ43_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBH2741368.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            21167..22069
                     /locus_tag="KRQ43_000999"
     CDS             21167..22069
                     /locus_tag="KRQ43_000999"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH2741369.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            22154..22738
                     /locus_tag="KRQ43_001000"
     CDS             22154..22738
                     /locus_tag="KRQ43_001000"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBH2741370.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            22953..23879
                     /locus_tag="KRQ43_001001"
     CDS             22953..23879
                     /locus_tag="KRQ43_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HBH2741371.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFNYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIGKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYILSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVENSLHRILEHSKEGRTSMLQDVEAHRPTEVDMF
                     SKNICKLGKKYSIPTPINQTLFYMIKVIESRF"
     gene            complement(23931..24821)
                     /locus_tag="KRQ43_001002"
     CDS             complement(23931..24821)
                     /locus_tag="KRQ43_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH2741372.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSQKYPDIYVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYNSHLLKDFSFDKLQDQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            25009..26040
                     /locus_tag="KRQ43_001003"
     CDS             25009..26040
                     /locus_tag="KRQ43_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBH2741373.1"
                     /translation="MLKKKSSLTLKTIREILPGLFISVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGAIVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            26334..27209
                     /locus_tag="KRQ43_001004"
     CDS             26334..27209
                     /locus_tag="KRQ43_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxoguanine DNA glycosylase"
                     /protein_id="HBH2741374.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     RGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            27227..28717
                     /gene="cls"
                     /locus_tag="KRQ43_001005"
     CDS             27227..28717
                     /gene="cls"
                     /locus_tag="KRQ43_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH2741375.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            28910..29194
                     /locus_tag="KRQ43_001006"
     CDS             28910..29194
                     /locus_tag="KRQ43_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBH2741376.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            29227..30855
                     /gene="groL"
                     /locus_tag="KRQ43_001007"
     CDS             29227..30855
                     /gene="groL"
                     /locus_tag="KRQ43_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBH2741377.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVIVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            31117..31857
                     /gene="larB"
                     /locus_tag="KRQ43_001008"
     CDS             31117..31857
                     /gene="larB"
                     /locus_tag="KRQ43_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HBH2741378.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            31941..32675
                     /gene="larC"
                     /locus_tag="KRQ43_001009"
     CDS             31941..32675
                     /gene="larC"
                     /locus_tag="KRQ43_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HBH2741379.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            32705..33124
                     /locus_tag="KRQ43_001010"
     CDS             32705..33124
                     /locus_tag="KRQ43_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HBH2741380.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKVTP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      33184..33285
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            33506..35041
                     /gene="guaA"
                     /locus_tag="KRQ43_001011"
     CDS             33506..35041
                     /gene="guaA"
                     /locus_tag="KRQ43_001011"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBH2741381.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTSITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            35580..37010
                     /locus_tag="KRQ43_001012"
     CDS             35580..37010
                     /locus_tag="KRQ43_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH2741382.1"
                     /translation="MILNQIFIEDGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPRNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGEYISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYIYGEAEVMPINIKCDESEYKNNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(37158..38033)
                     /locus_tag="KRQ43_001013"
     CDS             complement(37158..38033)
                     /locus_tag="KRQ43_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH2741383.1"
                     /translation="MINIRYLEILEAIEQTGTFTGAAKKLHITQSAVSHAIAELEQQA
                     ETSLFDRLPRGVCLTRCGISLLDEARSILTACRNLDKKISRLEECTPINIVSSITIAS
                     FLLPPILSRLKNSFPSLKVNVRVESANSAMDILKSGEADICFWEGIEPQGAFRTILLG
                     SYKLCVACAPTFPLSEQTLSLRQLCTFPLLLREQGSAIRDTLDSVLSLSNQKAYPVWE
                     SVNSFALIKAAEAGLGITILPENLLLDSLLHKKLRLIELDEIDMENKMLAILHKDKNI
                     TQPLEIILDNISNVL"
     gene            38153..38716
                     /locus_tag="KRQ43_001014"
     CDS             38153..38716
                     /locus_tag="KRQ43_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH2741384.1"
                     /translation="MNQSRKIYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKQFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCTAAIIPPLVILGLVSAF
                     YTTFISNAIVTAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSTMIPIAFFANFVM
                     SINVIFILSVCCFVCVMQVFYKKRENK"
     gene            38713..39279
                     /locus_tag="KRQ43_001015"
     CDS             38713..39279
                     /locus_tag="KRQ43_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH2741385.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKM
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     ILLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(39408..39644)
                     /locus_tag="KRQ43_001016"
     CDS             complement(39408..39644)
                     /locus_tag="KRQ43_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741386.1"
                     /translation="MLECFIAEDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(39954..43382)
                     /gene="uvrA"
                     /locus_tag="KRQ43_001017"
     CDS             complement(39954..43382)
                     /gene="uvrA"
                     /locus_tag="KRQ43_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH2741387.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFENELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFAKAINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLGNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKTPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPNAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPNKNYTALTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFTETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCNEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            43701..45935
                     /locus_tag="KRQ43_001018"
     CDS             43701..45935
                     /locus_tag="KRQ43_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH2741388.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMDEILNIDSFNGEGTIEIINSQGKTLFIGKNNELIKDLSYKYKDSADEP
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDVVLGELNK
                     LNSFTIIMTFITTCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSNFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            46191..48221
                     /locus_tag="KRQ43_001019"
     CDS             46191..48221
                     /locus_tag="KRQ43_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2741389.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDLIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENEIILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDEDMKWEDAVKISSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            48218..48670
                     /locus_tag="KRQ43_001020"
     CDS             48218..48670
                     /locus_tag="KRQ43_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2741390.1"
                     /translation="MNKLVNVKCSFKIHANSKEEAIVSLVDVVSKEGYLIDKNQFLED
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDIPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            48672..49727
                     /locus_tag="KRQ43_001021"
     CDS             48672..49727
                     /locus_tag="KRQ43_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBH2741391.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLIGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     IGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            49794..50102
                     /locus_tag="KRQ43_001022"
     CDS             49794..50102
                     /locus_tag="KRQ43_001022"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBH2741392.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            50206..51471
                     /locus_tag="KRQ43_001023"
     CDS             50206..51471
                     /locus_tag="KRQ43_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HBH2741393.1"
                     /translation="MKKLPIKTVVQRLLDLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKIADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLSVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVDKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKNEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            51559..52275
                     /locus_tag="KRQ43_001024"
     CDS             51559..52275
                     /locus_tag="KRQ43_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH2741394.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(52470..52763)
                     /locus_tag="KRQ43_001025"
     CDS             complement(52470..52763)
                     /locus_tag="KRQ43_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HBH2741395.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(52769..52984)
                     /locus_tag="KRQ43_001026"
     CDS             complement(52769..52984)
                     /locus_tag="KRQ43_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741396.1"
                     /translation="MRTLSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            complement(53529..54041)
                     /locus_tag="KRQ43_001027"
     CDS             complement(53529..54041)
                     /locus_tag="KRQ43_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH2741397.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKELSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVKQILDLPVKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            54491..54967
                     /gene="purE"
                     /locus_tag="KRQ43_001028"
     CDS             54491..54967
                     /gene="purE"
                     /locus_tag="KRQ43_001028"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBH2741398.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            54973..55671
                     /locus_tag="KRQ43_001029"
     CDS             54973..55671
                     /locus_tag="KRQ43_001029"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH2741399.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            55683..57050
                     /gene="purF"
                     /locus_tag="KRQ43_001030"
     CDS             55683..57050
                     /gene="purF"
                     /locus_tag="KRQ43_001030"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBH2741400.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            57044..58120
                     /locus_tag="KRQ43_001031"
     CDS             57044..58120
                     /locus_tag="KRQ43_001031"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBH2741401.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            58114..58707
                     /locus_tag="KRQ43_001032"
     CDS             58114..58707
                     /locus_tag="KRQ43_001032"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBH2741402.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            58700..60232
                     /gene="purH"
                     /locus_tag="KRQ43_001033"
     CDS             58700..60232
                     /gene="purH"
                     /locus_tag="KRQ43_001033"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBH2741403.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEVLKQKKNLRILKLAKIEDSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKAKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            60243..61493
                     /gene="purD"
                     /locus_tag="KRQ43_001034"
     CDS             60243..61493
                     /gene="purD"
                     /locus_tag="KRQ43_001034"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBH2741404.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKVYCAPGNAGITNVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMETILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMLDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            61518..65324
                     /locus_tag="KRQ43_001035"
     CDS             61518..65324
                     /locus_tag="KRQ43_001035"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBH2741405.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAVPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKTFTDDKLFE
                     ASYGNIVLELANDDLCMLEGYNYVVLGSTTKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERVGA
                     NANIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVFKNIIGEKDQKIFES
                     GVKYFR"
     gene            65530..66402
                     /gene="rfbD"
                     /locus_tag="KRQ43_001036"
     CDS             65530..66402
                     /gene="rfbD"
                     /locus_tag="KRQ43_001036"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBH2741406.1"
                     /translation="MKILITGSNGQLGKELVSQLEAINQSINQPKYVILATTRNDLDI
                     SNQTNIDNFILHNKPDVIVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LVHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFELKNIDIKVNPIKSNEFKCKAQRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            66511..67392
                     /gene="rfbA"
                     /locus_tag="KRQ43_001037"
     CDS             66511..67392
                     /gene="rfbA"
                     /locus_tag="KRQ43_001037"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBH2741407.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLKITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDMQYGR"
     gene            67429..67986
                     /gene="rfbC"
                     /locus_tag="KRQ43_001038"
     CDS             67429..67986
                     /gene="rfbC"
                     /locus_tag="KRQ43_001038"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBH2741408.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFCDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVRYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFNYKCTNYYYPEFEHGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICIRR"
     gene            68024..69007
                     /gene="rfbB"
                     /locus_tag="KRQ43_001039"
     CDS             68024..69007
                     /gene="rfbB"
                     /locus_tag="KRQ43_001039"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBH2741409.1"
                     /translation="MKKILITGGAGFIGSNFVHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDSSNYKFVKGDISNREQMYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSPINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLDKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            69046..69714
                     /locus_tag="KRQ43_001040"
     CDS             69046..69714
                     /locus_tag="KRQ43_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH2741410.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNSSSGFDMIMMTLLK
                     ALSQNNQQTSNGYNLSSNSENLFDELGSVVNNTASRFIDVDTKDKSVKSRIENAIEQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            69723..70151
                     /locus_tag="KRQ43_001041"
     CDS             69723..70151
                     /locus_tag="KRQ43_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HBH2741411.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            70175..70489
                     /locus_tag="KRQ43_001042"
     CDS             70175..70489
                     /locus_tag="KRQ43_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH2741412.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNEKLSVRLSKIEDSD
                     VN"
     gene            70641..70916
                     /gene="flgM"
                     /locus_tag="KRQ43_001043"
     CDS             70641..70916
                     /gene="flgM"
                     /locus_tag="KRQ43_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBH2741413.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGVKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            70921..71337
                     /locus_tag="KRQ43_001044"
     CDS             70921..71337
                     /locus_tag="KRQ43_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBH2741414.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDRYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTATYNSYGNIRK"
     gene            71355..72665
                     /gene="flgK"
                     /locus_tag="KRQ43_001045"
     CDS             71355..72665
                     /gene="flgK"
                     /locus_tag="KRQ43_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBH2741415.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGNTVSKYDYY
                     NTIETIINEPSDYGISAGIDDFFKGWESLAKDINSDSKKSLVVENASNLATLISESYK
                     KLNKLKGDIDDNINSEIKQINDMLKSLEDLNKSIDVISGSGSTPNDLLDERDRILDDL
                     SFKLDLENSDVKNMLSDGKLELNELKNADGTWKTGVSGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKVNPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESVGLDSQKVNQDEVNQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            72684..73616
                     /gene="flgL"
                     /locus_tag="KRQ43_001046"
     CDS             72684..73616
                     /gene="flgL"
                     /locus_tag="KRQ43_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBH2741416.1"
                     /translation="MRVSTGMMSSNYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            73632..74024
                     /locus_tag="KRQ43_001047"
     CDS             73632..74024
                     /locus_tag="KRQ43_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HBH2741417.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDSLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            74018..74230
                     /gene="csrA"
                     /locus_tag="KRQ43_001048"
     CDS             74018..74230
                     /gene="csrA"
                     /locus_tag="KRQ43_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBH2741418.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            74252..74647
                     /gene="fliS"
                     /locus_tag="KRQ43_001049"
     CDS             74252..74647
                     /gene="fliS"
                     /locus_tag="KRQ43_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH2741419.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            74647..75003
                     /gene="fliS"
                     /locus_tag="KRQ43_001050"
     CDS             74647..75003
                     /gene="fliS"
                     /locus_tag="KRQ43_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH2741420.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELIRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            75024..76547
                     /gene="fliD"
                     /locus_tag="KRQ43_001051"
     CDS             75024..76547
                     /gene="fliD"
                     /locus_tag="KRQ43_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBH2741421.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLKVIGNDNLAQQIANDNGIT
                     FANDASGNKVASVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            76550..76885
                     /gene="fliT"
                     /locus_tag="KRQ43_001052"
     CDS             76550..76885
                     /gene="fliT"
                     /locus_tag="KRQ43_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBH2741422.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISSKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            76987..77859
                     /locus_tag="KRQ43_001053"
     CDS             76987..77859
                     /locus_tag="KRQ43_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HBH2741423.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTTN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTDAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            77952..80093
                     /locus_tag="KRQ43_001054"
     CDS             77952..80093
                     /locus_tag="KRQ43_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH2741424.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRSSIESELIIVDTGSTDD
                     TINISRKYTENVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNIDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFEELKENDNSPYTNYQLGKNFIILGKYHEAL
                     YYLEKSYELYSKLESAPGYLITSLVKTYLYLGKHKKCEKLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYESVISEYNNIEDMEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YKNIEEVINNIKDDEKEHVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKVAFEDKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDI
                     KKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYRNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNDANEKLEYIHSMRKLLNEYPFYNKIIKILISELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKSLVDDYSKTFMDDVKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            80117..81994
                     /locus_tag="KRQ43_001055"
     CDS             80117..81994
                     /locus_tag="KRQ43_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH2741425.1"
                     /translation="MNTPIVVNEKSKDIIKDWQYTYTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFMFAHKINTSNINLWKYRLKLVGFCMLIKKSVLDNVGVLDELFTPGNFEDDDLSFR
                     MLESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIADIEKVKLDYEKDFFDYIILGDVLEHLTDPWKIVNELKQYLKKDGCLISSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSVTATSMPLSEID
                     NRFIDTMCKESCKEMRQQYESYQYIVKATKSIDTKRYSSISMVNLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLVDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSKKVQSESDIQDILYFIEGKRY
                     E"
     gene            81987..84101
                     /locus_tag="KRQ43_001056"
     CDS             81987..84101
                     /locus_tag="KRQ43_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH2741426.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDAFIINKNFIYDILEIFKKNTDVGMIGVAGVKDI
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVANINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLDIVSKIAHFS
                     VFNHTGLYSCEKCERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAIDDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKEKQSEIKHFVIDKHCIEIKNYIDKIYKEANHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            84110..85105
                     /locus_tag="KRQ43_001057"
     CDS             84110..85105
                     /locus_tag="KRQ43_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HBH2741427.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIIYKGEEILAVVPACETYENGERVFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLETYLQEQSFNKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKK
                     DILANFRYSKRRYFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            85197..86429
                     /locus_tag="KRQ43_001058"
     CDS             85197..86429
                     /locus_tag="KRQ43_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBH2741428.1"
                     /translation="MKRLMILGSIKYFENIVMSAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEIFDENNENMIENF"
     gene            86449..87393
                     /locus_tag="KRQ43_001059"
     CDS             86449..87393
                     /locus_tag="KRQ43_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HBH2741429.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSDIFLYNMKDAKLKAILDGNYITA
                     FRTAAVAGLAIDTFAKKDFNTISIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFIKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYNVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLNCEEIELKEPKEKYWI"
     gene            87487..87894
                     /locus_tag="KRQ43_001060"
     CDS             87487..87894
                     /locus_tag="KRQ43_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FdtA/QdtA family cupin domain-containing
                     protein"
                     /protein_id="HBH2741430.1"
                     /translation="MDKYNLIKFLSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKESIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNM"
     gene            87981..89072
                     /locus_tag="KRQ43_001061"
     CDS             87981..89072
                     /locus_tag="KRQ43_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HBH2741431.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVRHFEEE
                     FASYVGSKYCVGLASGLDALIIAFRALGISEGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASKMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKNGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFVGMEDEEVSYIIKIINEY"
     regulatory      89381..89471
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
BASE COUNT        35272 a         9664 c        15747 g        29065 t
ORIGIN      
        1 attaaaataa attatatatg aaaatatata tgtataagtt tattctgcgt gagtagaatg
       61 aatttgtcaa gtttaattta gttgtaattg tatcttttat taaaaataat ataaattaaa
      121 acatataaat aaaatatttt atacaatata ttgtaaagga ggtaactttg atgaaagcag
      181 aaaaaacaag tatatatcca attattaaaa ataatttaaa caaaatatca attgttgaat
      241 ataaaaaggg tcaaagattt gtagcatcag ataaagactt acaagaagtg ttctttataa
      301 tagagggagt tgcattagtg gagtgtacta ctagaggagg aaataaattt cttgttgaca
      361 ttgtacctga aaatgaattt ataggcaaaa tcagttacat atatgaacat aatttgaaat
      421 gtgatatatt tgcaaagacc aatataaaat tatttcgatt tgaaaaaaat gtatttgaag
      481 agttttatct caaaccagat tttattgcac tatttcacag aaaatgtaca agaagaatat
      541 atgaattata taaaaccaga atggtaagag aactattttc ttgcacagaa gttattgcct
      601 attgtatatc aaataaacaa gaaaataatg tctgcaatat aaaagctatt cgtaatttca
      661 gtgaaatcta ttcaattagt agaaaaagta gataccattc tctgctaaag ttaactgaaa
      721 aggagatagt aaaaaaaatg ggtaatacat atgaaatttt aaactatgat gaattacata
      781 aattggcatt tgaagtaaaa gagtttttgg aagatgagta aaaattgtta cttaatcaaa
      841 ataaagtata ataatttctg taaaaaatag aaatagtctc actgaaaatc aaaaatactt
      901 tagttatttt caatgagact gtttagaaat attgtatact tataatgtat agtataatta
      961 ttaatcaatt tcctttacta tattaatagc ccatttttta gataatgctc taggaacacc
     1021 aaatataaac ttaaccactt cttcactata agtgagtaaa acgagtacaa atataggtgc
     1081 acctttaaat gcagctataa aagttagagg aatagaagct aaccacatac atcctaattc
     1141 tagaaataga gcatatttag tatctcctcc acttcttaaa ataccaatta taaccaatgt
     1201 attaaaagat ttaagagcca ttagtattcc catgataaag aatatcttag ttatatcaga
     1261 agctaagcta tcagaaacac taaacatttt taataataat ggtatattta aaattaaaat
     1321 aattccaagt attaaaccag ctgaaaatac aagtatagaa aactttttag catattcaat
     1381 ggctctttta atatggtcag ctccaagttc atttccaagc ataatagatg caccagatgc
     1441 aatacataca gctgtcatta tgaagaaatt acctgtactg gttgctatct ggctagctgc
     1501 tatagcagaa gtaccagctc ttgcatatgc aacagaatac aggacagttc caattgccca
     1561 tacagagtca tttacaaata taggaaagct ttttgatgaa aaagatttta taaaaatttt
     1621 atcaatagct tttagatttt ttagaccaaa ctttaatata tagtcttttt tataaaggta
     1681 aacataagta atcattaaaa ttaattcaca tattctagca ataacagtag ctagagcagc
     1741 accttttaca cccaatgcgg gaagaccgaa gttaccaaat ataaatccat aatttaaaat
     1801 aacatttgtt acaagtgcaa atgcactaca aatcatacct aacttaggat ttctaacacc
     1861 tcttgaacca gtactaaata cagtacttac agcaattaat ggataactaa atactgcaat
     1921 actaaagtaa tctatacaaa gttttaccac ctcagaatca tacgaaaata tgtgtataat
     1981 tggctttggt gttagtaaag caggaataac aaatacaaaa cttaaaacaa ttgccaatac
     2041 acaagtaaga cctgtgactt ttcttatatt actcacatcc ttctttccat aaaactgtga
     2101 aataaaaact ccagcacctc ctgtgatacc agataaggac atattaaaaa gaaagaaaaa
     2161 ttggtttgca actccaactg aagctacaga tgtctccccc aaactactta tcataattgt
     2221 atctattaca tttacagaag tagaaattaa gttctgtatg ataataggta tacataaaga
     2281 tagaagtatt ttataaaatc ttttattttc gtcttttaaa gaaaatagtt cttgcaaata
     2341 atcctctcct ttttacataa attcttccca ctcatcatat agagaggcaa ggttattttc
     2401 taaattaatt ttttcttggc taacttcttt agctttatct ggattagagt atacttcttc
     2461 ttgacataaa agtatatcta atttttcaat ttcaatctct aacttttcaa tttctttttc
     2521 tatattttgt ctttttattc tatttttctt ttctatttct ctttgttctc tctcttttct
     2581 tttttcatct tttatttgag ttctagtttt ttcttctttt tcttctataa tactcatctc
     2641 ttggatttgc ctttttttat ctatataata atcataattt cccagatatt cagtaattcc
     2701 attttcatct aaaactaaaa ttttatcaac aacagtattt agaaagtatc tatcatgtga
     2761 tattgtaaat atagtcccat cataattagt taatgcctct tcaaggactt ccttagaatc
     2821 aatatctagg tgattagtag gctcatctaa taacaataag tttgcatttg atagtataag
     2881 tttaagtatg gcaactctag ctctttctcc accactcaat gtagaaatct tcttaaaaac
     2941 ttcttcatct acaaataaaa atgcccctaa catatttctc aaagtagttt gagtaagatg
     3001 agtattattt tcccaaatct catcaattat tgtgttatct aaattaagag ttttttgttc
     3061 ctgatggaag taggaaacat gtacattagt tccaaattta atattgccac taagaggttg
     3121 tagttcatta gttattattt taaataatgt agatttgcca acaccatttg cacctataag
     3181 tgcaactttt tcccctctat atatatctaa atccaagtct ttaaaaagta ttctttctcc
     3241 ataacccata gatacatctc taatttgaag aacatcatta ccactctgga cagaaggcgt
     3301 aaattgtata cgagcttttt tcctataagc ttctggttta tctaaaacgt ctaccttgtc
     3361 taatgctttt tctttacttc ttgcacgctt taggtgtttt tctctaccat aagcttttag
     3421 tctttcaatt gattcttctt gcttttttat ttctttttgt tggtcttcaa atttcttaag
     3481 ctctagttct ttttctattt tagataactc aacaaattta gagtagttac cattatatac
     3541 tttaagtttt ttgttgtgaa cttcaaaaat tctatttacg gattggtcta agaaatatct
     3601 atcatgagat attaacatga cagttccttt atattgtttt aaaaatactt ctaaccattc
     3661 tattgcttca gagtctaagt ggttagtagg ttcatcaagt aacaatagag ttggtttctt
     3721 aagaagtaat tttcctaaaa gaactctagt tttttcacca ccagaaagta tgcttattgg
     3781 cttatccata tcattgtcac taaatcctaa tccttttaga actcctttgg cttcagattt
     3841 atatccatat ccatttaaat ctgaaaataa ttctagttta tgtgaatatt catccatgat
     3901 tttttctata attggagagt ttgtttttgt actttcttca gatattttaa cctccaattc
     3961 tcttaaatag gattccattt ctatcaaatt tttaaaaact tctagcactt cttccaaaat
     4021 agtattatcc gaataaaaat tggtattttg ttctaaatat ccgatttcac aatctttaga
     4081 agtataaata tctccactat catatccata aattcctgaa attattttaa ataaagtagt
     4141 ttttccagta ccattaacac cgattatacc aattttatcg ccttcattta ctgtaaaact
     4201 aatattttct aatatagaat ctataccaaa acttttattt aagttattac atgacaaaac
     4261 aatcataaat ttctacctcc ttgaactatc taaaattata atgttttgat ataatataat
     4321 caaggttata tgtattagtt ttgaaaaaga aatattttat tgtgaatcaa acaaaaaaga
     4381 ggacactttt aggaggtgaa gatgttggga aataaaaata tatcaatggc agttataaga
     4441 aggctcccaa aatatcatag atatcttgga gacttattag atagggatat acaaagaata
     4501 tcttctaaag aattgagtga tataataggg tttaccgctt ctcaaataag acaagattta
     4561 aacaactttg gtggatttgg acaacaagga tatggttata atgtagaagc tcttcatact
     4621 gagataggta aaattcttgg gttggatcga ccatacaacg cagttcttgt aggagcaggt
     4681 aacttaggac aagctatagc caattatgca ggatttagaa aagctggatt cgagataaaa
     4741 gctttatttg atgcaaatcc tagaatgata ggtttaaaga taagagagtt tgaagtatta
     4801 gattcagata ctttagaaga ctttataaaa aacaataata tagatattgc tgtattatgt
     4861 atacctaaaa atggagcaca agaagttatt aatagagttg taaaagctgg aatcaaaggt
     4921 gtatggaatt ttgcaccttt agatttagaa gttccgaaag gtgttatagt tgaaaatgta
     4981 aacttaacag aaagtttatt taccttatcg tatttaatga aagaaggaaa gtagacaact
     5041 taaacatatt aataatgagc agttgtgaag agtattgaga aagtcagaag atttaatatt
     5101 aaatcctctg gctttttgaa atattaggat aaaaatttaa ataatgtatg gaaataaaca
     5161 atattaagga gagtggtttt tgtggaggaa ttatggaaaa aggcaattga atttcatggt
     5221 catgaatgtc cagggttagc tataggattt aaagcagcac ttgcagcaag aaaatattta
     5281 ggatgtaaac agtcaggaga tgaggaaatt gtatgtattt ctgaaaatga tgcttgtgga
     5341 atagatggta tacaagtcgt gctaagttgc acaatgggta aaggaaattt actacttagg
     5401 atgactggga aatcagtata tcatttcttt aatagggaaa atggaaaatc tataagaata
     5461 tatgtaaagt caaagccatt tcaaatggat agagaaggat acaaaaagta cttattagaa
     5521 agtgattttg aagaaatatt tgagattaca gatactaagt taagacttcc tgaaaaagca
     5581 agaatattta aatctcttaa atgtgaagtg tgtggtgaat ttgcatctga gcaatatata
     5641 aggattgaag aaggaaagaa agtatgtctt gattgcttta ataaatatga aagattttat
     5701 gaggagtatt aaaattataa attagattaa agttaaaagt attagatatg tactaacagt
     5761 attttaagat gaattaggta gcaacataat aaaatatata aataatatta cttgaaccat
     5821 acataattaa aaagaggctg attagtattt agaaaataaa atcagtctct ttatgaataa
     5881 cgaattatta ttctggttga ggtgcatcta caggacaagc tcctgcacaa gaaccacagt
     5941 ctatacaaga accagcatct ataacatatg cgtcgtctcc agctgatata cagctaacag
     6001 ggcattcagc ctcacaagca ccacagctta tacaagcgtc agtaatttta tatgccattt
     6061 tgaaatcctc ccttttatat gtattgtaat tcaataacat tataacaaat attattgaat
     6121 ataacaatta aattaattct acaacaaaaa ctttattatg atattcttgt tttaaagttt
     6181 tacaataaag tttaatctgc ttatattttt atttatttta aagaagttta ttttaaaaat
     6241 aaaattaaat ttaaaaagtt atgtattgat tatatttaaa aatgttatac tctaaaaaag
     6301 tatattttat tttaaaattt attaatacaa aggagattta ctatgaaaaa taaattagtt
     6361 tacatatgta ttatgagtct attgctattt gtagtaggat gttctaataa tccaaataag
     6421 gaaagtacca ttaaaaaaga ctctaagaat aaccaaagcc aagttaaaga agaaaaaaga
     6481 gaacctgtga aaaaagatat aactataagt ttcgctggtg atgtaactat ggggaactat
     6541 aaaggttcat catattatgg cagttttgac catgaattta aaagacaagg agaagattac
     6601 aattattttc ttaaaaatgt aaaacctgta tttgaaaaag atgacttaac agtggttaat
     6661 ttagaaggtc cacttactac agcgtcaaat gcaaaagaaa aaaaatttgc atttaaagga
     6721 aagcctggat atgtaaatat tttaaaatct ggaagtatag aggcagtaag tattgcaaat
     6781 aatcattcag aagattattt tgaagaagga atgaaagata cacagtttat attggatgag
     6841 aataaaataa attattttgg attagggaaa gatgctgttg tagatgtcaa aggaattaaa
     6901 gtgggtctat tagggtataa tggattatca actgaatata atgaaaaaaa tttaaaacaa
     6961 atggaagatg atattaagtc cttaaaaaag aaatcggatg ttgttgtagt gtactttcat
     7021 tgggggatag aattagatta ttatccagat aaaaaacaaa aagattttgc tcattatgct
     7081 atagacaagg gagcagattt agttatgggg tctcacccac atgttattca aggaatagaa
     7141 aagtataaaa ataagtatat agcttatagt ctagggaatt tttgctttgg aggaaataag
     7201 aatccttctg atacagatag ttatatatat caacaaacct ttactttttc agataataaa
     7261 ttaacttcaa ttaaagagcc aaatataata ccaacctcaa taacatctag tagctccaga
     7321 aataattatc aaccaaaagt attggatgga agtgagaagg atagagtttt aaataaactt
     7381 gaaaaaataa gcaaagattt aaataaataa aatgtaaaaa aaaataaata tatatattta
     7441 ttttaataat ttatattttg tttagggtat ggtaaatcgt ggtattaaat aagtagattt
     7501 taatagttaa attatagtca attataataa agctatttaa tctacttttt taatataaaa
     7561 atataagggg gaatttgtaa tggcttgtaa cacttgtaaa atgtgcgaaa gtgcagacaa
     7621 gaaattagaa agttttgtag cttcaaagga tgttgaaaca gcatttcata gaacagaaga
     7681 tcagaaagtt aagtgtggtt ttggacttca gggggtttgt tgtagactct gttcaaatgg
     7741 accatgtaga gtaactccta aatcaccaag aggtatatgt ggagcagatg cagacactat
     7801 agtagcaaga aactttttaa gagcagtagc atcaggagca gcttgttatt tacatgtggt
     7861 agaaaataca gctaagaatt taaaaaatgt tggaataact aaaggtgttg ttaaaggaga
     7921 aaaaacatta aatcaattag cagagatgtt tggaatagaa agtgatgaaa agtatgataa
     7981 atgtataaag gttgcagaca aagttatcaa cgatttgtat aaatcaagag atgataaaat
     8041 ggaattagta gaaaaaatag cttatgcacc tagagtgaaa aagtggaaag agttaggtat
     8101 aatgcctggt ggtgcaaagt cagaagtttt tgatgcaata gtaaaatcat caacaaattt
     8161 aaatagtgat ccagtagaca tgctagttaa ttgtttgaac ttaggtatat caacaggatt
     8221 atatggtctt acactaacta atcttttaaa tgatgttatg ttgggagaac cagttataag
     8281 aatggctcct gtaggattta atgtaataga cccagactac ataaatataa tgataacagg
     8341 ccatcaacat tcaacatttg caaatttcca agatagatta aaagatgaag atgttataaa
     8401 attagctcaa tctgttggtg caaaaggctt taagctagta ggatgtacat gtgttggtca
     8461 agatttacaa ttaagaggag aacattatca agaagtattt gctggacatg caggtaacaa
     8521 ttttacaagt gaggctgttt tatcaactgg agcaatagat atagttcttt cagaatttaa
     8581 ctgtactata ccagggcttg aaccaatagc agataaatat aaagtaaaaa tggtttgttt
     8641 agatgatgtt gctaaaaaag cgaatgcaga atacataggt ttagacagaa gtaaattaga
     8701 tgaacttagt aacactttaa tagaaaaagc attggagtct tataaggaga gaagaggaag
     8761 tattgagata gatataccaa aagaccatgg atttgaacaa tctttaactg gtgtaagtga
     8821 aaagaacctg aaagcgtttt tgggagattc atggaaacct cttattaatt taattgcaga
     8881 aggaaaaatt aaaggtgttg cagctgttgt aggatgttca aatatgacag caggaggaca
     8941 tgatgtaaat actgttgaac ttactaaaga attgattaaa aaagatataa tagtactatc
     9001 tgcaggatgt tctactggag gattagaaaa tgttggtctt atgtcacctg gagcagaaga
     9061 attagcagga gaaaacttaa aagaagtatg taagacttta ggaataccac cagtattaaa
     9121 ctttggacca tgtctagcta taggaagact agaaatagta gcaacagaat tagcagctga
     9181 acttggaatt gacctaccac aattaccatt agtgctttca gctccacaat ggttggaaga
     9241 acaagcatta gctgatggag cgtttggtct tgcccttggc ttacctcttc atttagcttt
     9301 acctccattt ataacaggag gaaaattggt gacagaagta ttaacagaaa aattaaaaga
     9361 cttaacagga ggacatgtta tagtgaatcc agaccctaaa tcttcagcta atcaattaga
     9421 agaaataata atagatagaa gaaaaaattt agggttaaag gatgtggaat gcaatgcata
     9481 gaatttttat aaataaagat ttatgtacag gatgtaagag ctgtgtacta gcatgtatgc
     9541 taaaacacaa taaagattat gacatgtaca ctcttgattt agaaaatata gataatgata
     9601 gtagagggca tatagaatta gatagtaaac ataataatcc agttccaatt ctttgtagac
     9661 actgtgatga acctgaatgt gtattagcat gtatgagtgg tgcaatgcat aaagatagtg
     9721 aaagtggaat cgtttcatat gatgaagaga aatgtggttc atgttatatg tgtgtaatgt
     9781 cttgtccata tggattatta aagccagatg atagaagcaa gcaaaacata cttaaatgtg
     9841 atttatgtaa agatgaggag tatcctagat gtgtagctaa ttgcccaagt ggagcaattg
     9901 aattacagaa ggaggaaaat gatgaattat gtagtgttag gggctagtgc agctggtata
     9961 aatgcagtaa aaacattaag agaattagat aaagattcaa atatagtagt aatttctaaa
    10021 gatgaaaacg tatattcaag atgtatgttg catcacgtta tatctgaaca cagaacttta
    10081 aaacaaataa attttgttga tgaagatttt atggagcaaa ataatgtaaa atggattgca
    10141 ggtaagactg ttaaaggtat agacataaat aaaaaggtag ttcaaacaga agacattact
    10201 gtaaattatg ataaactttt aatagctaca ggtgcatctt ctgctattcc tcctataaaa
    10261 aatttaagag atggaaattt tgtatattct gtgagaaaca tagatgatat ttataaaata
    10321 aaagaaaaag cacaaaattc taaaaatgta gttataatag gtgctggttt agttggtata
    10381 gatgcattag tgggattatt taaatatgag cagttaaata tttctgtagc ttttatggaa
    10441 aagtacattt tagatagaca attggatgaa tatacagcat cagtgtatga aaataagttc
    10501 aaagaaaaag gtgtaaaatt ttacccaagt gcatcaatac aagaaattgt attggataac
    10561 agtaaaaatg ttacaggtgt tgcattttca aatggtgaag ttttagatgc agacatggta
    10621 attgtagcta caggggttaa accaaatgct gactttttag atgggacagg aatagaatat
    10681 gatagaggta taataataga tgatatgtgc caaacaacac aaaaagacat atatgcagca
    10741 ggagatgttg taggtaaaaa tgctatttgg cctctggcag taaagcaagg aattgtagct
    10801 gcctataata tggttggaaa agataagaag atagaagatg aatttgcttt taaaaatagt
    10861 atgaatttca tggatatacc aactatttct ataggaatga atacacctgt agatgatagc
    10921 tataaagtat taaccagaca tggaattaat gattataaga agtttgtttt taaagataat
    10981 gtaatctacg gagcagttat acaaggagat atttcatatg taggtgtatt aacttattta
    11041 ataaaaaata aagttgaaat atatgattta gaaaatagga tatttgatgt atgttatgca
    11101 gactttttta atataaaaga aaatggagaa ttttgttata gtgtatagta tatacgtgga
    11161 gtaaggttta taaatacagt aaatcaataa atagagttat tctaaaataa gaaaaatgac
    11221 aaatcttatt tagaaatagc tctatttttt gtaattaaat ttaaattata ttcaatttgt
    11281 aaaatattat tttgaacaat tatacatata ctctctagtt agaggtaaat cattttttat
    11341 acctttagtg aaaagtattt gatgtatatc tataatacca gtgttgaaag cagcagcaca
    11401 agaacaaagg tataaatccc acattcttat aaacttatca tcaaacattt ctttaatctt
    11461 tggaagattc tcagagaaac ttttttgcca gtatagtaag gtttttacat aatgtaatct
    11521 taaactttct acgtctatag tatgatattt gtaatcacta caaatatgta tcatttctct
    11581 taggctagga ataactcctc ctgggaaaat atattttttt atccaagggt ctccataaga
    11641 ttcctgcaat ccacttatat agtgaagtaa aaacaatcca ccatctttta aaacagcatt
    11701 tacgttttta atgaaaagtt catagttttc tctaccaaca tgttcaagca ttccaacgct
    11761 tacaactcta tcaaacataa ggtctgattt ttttaattct ctatagtcca taagtcttac
    11821 ctcaagatag tcttgaaggt tctcttcttt aattcttgcg ttaaattcct taaattgctc
    11881 ttcgctaagt gtaattccaa cgccgtgaat tttatatttt tttgcagctt ctattagtaa
    11941 aaatccccaa ccacaaccaa tatcgagaag gctcatacct tcctctaaat ttagtttagt
    12001 taatatgtgg tgaactttat tgacttgagc atcataaaga gtatcattat catttctaaa
    12061 gtatgcacaa gaataactaa gtgtcttatc taaccataag ctataaaaat cgttgccaat
    12121 gtcatagtgg gcatgtattt ctttcttctg atgtctcatt gaatttgatg agtgcaatag
    12181 atgttttaca gctgaattat caatattgaa tttgtctatt tgttttaaaa gtagatttaa
    12241 agttaagaat aaatctccct caacttcaat gtctctattt atgtaggctt ctccaagtgc
    12301 taaagatgta ctttttaata gttcagactt gctaatatca ttatttacta taactttgaa
    12361 ctgaggggag ccctctccaa ttagaaattc ttcctcatct ttaagcctaa ctagaaatgg
    12421 tgtttcacca aatttctcta aatagtcttt taaaaaattt tttgtaatat tcatattacc
    12481 agctccttct aatgtaaatc cagtaagttt ccctgcttaa aatatattat agtccttttt
    12541 ttaaaaaagt aaaatttttt caataaattt tttatttaaa ggaaatttat tttttataaa
    12601 gaaatttcat gttgtagtat attttttgct tataaatttt ggtactggat ataatattaa
    12661 actgttaatg atataataaa tttaatctat aaagtaaata aaattttgta ataaatagtt
    12721 aaagctattt tataaggaga tatatgatgg aagtatatgc tttggttggg tcaagtggca
    12781 cagggaagag ctttaaggct ttagagttcg catatgaaaa tgatatagaa tatataatcg
    12841 atgatgggat tttaatatac aaaaacaagg ttttagctgg gatatcggca aaacaagcaa
    12901 atactactat agaagcagtt aaaagggcta ttttttataa tctggagcat agacaagaag
    12961 ttagagaagc aattaaaaaa gaaaatataa gaaaaattct tattattggg acatcaaaaa
    13021 aaatggttaa tcaaattgta gagagattgt caattggaag ggtctgtaag tttataaata
    13081 tacaagatat aagtactaaa tatgaaatag aaatagcaaa acaagctaga aaagaaggaa
    13141 atcatgtaat tcctgttcca gccgttgaga taaaaagtat ggcaagtggt ctcagtataa
    13201 attctttgaa gagacttttt agaaaaggaa ataataggaa tatggtagtt ttagaaaaaa
    13261 caattataag accaactttt agttatatag gaaagtttta tattagtgct gatgtaatta
    13321 aacagattat tgaatatgaa gtatacaact ttggaagcat tgatagaata aataaaatca
    13381 atatagagaa ttgcaataat tttatgaata tttttgtaag tataaatatc aatgatttag
    13441 aaactataaa aaaaattgaa gacatacaac agacaataaa aaagtctatt gagaaaatga
    13501 ctttagttaa tgtacaaaaa atagatatta acattcataa aattaaaaaa ataaacttcc
    13561 tccaatgtta aaaaataaac tgagaaaatg atatactaat ttgcaataaa gtgtgctata
    13621 attaaactgt aaatttagga aatggttttt tctaaatgga gtatacataa ttataacgta
    13681 tttataaggg ggctttcaaa tgtcaggaaa agatgtaaat gtcttcgaga tggcgcaatc
    13741 tcaagtaaaa aatgcatgtg ataaattagg tatggaacca gcagtttatg aattattaaa
    13801 agaacctatg agagttatag aggtttcaat tccagtaaaa atggatgatg gttctataaa
    13861 aacttttaaa ggatttagat cacaacataa tgatgcagta gggccaacaa aaggtggaat
    13921 aagattccat caaaatgttt caagagacga agtaaaagct ttatctatat ggatgacttt
    13981 caagtgttct gtaacaggta taccatatgg tggaggtaaa ggtggaataa tagtagatcc
    14041 atcaacttta tctcaaggtg aattagaaag attaagtaga ggatacatag atggaatata
    14101 taaattaata ggtgaaaaag ttgacgttcc tgcaccagac gtaaatacta atggtcaaat
    14161 aatgtcttgg atggttgatg agtacaataa attaactgga caaagttcta taggtgttat
    14221 aactggtaag ccagttgaat ttggtggttc tttaggaaga acagctgcta ctggatttgg
    14281 tgttgctgtt actgcaagag aagctgctgc taaattagga atagacatga aaaaagctaa
    14341 aatagctgtt caaggtatag gaaacgttgg ttcttataca gttcttaact gtgaaaaact
    14401 tggtggtact gttgtagcta tggctgaatg gtgtaaatca gaaggttctt atgctatata
    14461 caatgaaaat ggtttagatg gtcaagctat gttagattat atgaaagaac atggtaactt
    14521 attaaacttc ccaggagcta agagaatatc tttagaagag ttctgggctt cagatgttga
    14581 tatagtaata ccagctgcat tagaaaactc tataactaaa gaagttgctg aatctataaa
    14641 agctaaatta gtttgtgagg ctgctaatgg accaactact ccagaggctg acgaagtatt
    14701 tgctgaaaga ggaatagttc ttactccaga tatattaact aatgctggtg gagttacagt
    14761 ttcttacttc gagtgggtac aaaacttata tggatactac tggtcagaag aagaagtaga
    14821 gcaaaaagaa gaaatagcta tggttaaagc atttgaatct atttggaaaa tcaaagaaga
    14881 gtacaatgtt acaatgagag aagctgctta catgcattca attaagaaag ttgctgaagc
    14941 tatgaaatta agaggatggt actaagattt actcttaata aataatagga tataattatt
    15001 taagatataa aggggctgta catagtacag cccttaaatt atgtggctta caatgaagta
    15061 agctattttt gttttaactt ataaataact tgataaatta tgtaatttag aatgcataaa
    15121 taagatgggt gaaaattaat ggttgattta attttgaatg tattttttac caccacatga
    15181 ttacaaatta gaggagttag attggatttt tggacatgaa cttatgtatt ttaaaagcaa
    15241 agaccttcat ttaaagtatc tagtattatt tttaaaaata gtatattggt ttaatccatt
    15301 tatatatata atggaaaaat atatggattt ggattgtgaa ctttattgtg atgagagagt
    15361 tttaaaaaat tgtactgtac aacaaaagca agaatatgct ctaactattg taaattcaat
    15421 gaaaagaggt ataaattttt caaataaatt tgtaactgga ttaaataaac aatctgatat
    15481 tagaaaaaga gtaatgaaca tgttcagtga aaaacataaa aatggtatct taatggcttt
    15541 gattataagc ttgttttctt ctattacatt ttttaaattc gattcaacta gtcttattga
    15601 agagaatgat ttcttagaga ggtcaagata tgcgtttgaa ggaaggcaag aagacatgtt
    15661 tgtaacaata gattctacat atgcagatgc acctataaaa cttagaaaag agcatgaaga
    15721 aaactgtaga gtcaatggaa tagtaccaaa agattcagat tcaatagaaa ttattcctag
    15781 attttataaa gattgtatgg atttaaaaaa ataagttaga cttaatattg atgttgatat
    15841 tatgaatttt ttatatttaa gcaattgaaa attttattat agattcaatt ttatatgtgt
    15901 ttaagtatga aatttataga tagttgaaat aattaaatat gattgatgca taggaatcat
    15961 tactaagcta taattaatta taggggagtt taaataaatt atgagttaca caattataaa
    16021 atgataaaaa atagttatct gttacaaaaa atgtatcttt ttaattaata aagataatat
    16081 gaaaacttaa aaggcaaata aacttaaaca taaaatactc ttaaataaga taggagaaaa
    16141 atgtatgtct aactttattc taaatgggat ttttagaaca gttatagtaa gtagtctaag
    16201 cattcttctg atattgattt tcaagaaaaa tgtatttaaa agatttagca aaaaatttaa
    16261 ttattatata tggatgatag ttgttattaa attattttta ccatttacat attatacttt
    16321 tacaataaat atcttgagaa gtaaaaaaca cattaatatt aataacataa atttagaggg
    16381 atttaataat gtttcaacta taagtaataa tattatattg tacacttgga ttataactgt
    16441 agtagtgtat ttaatttaca ctatatttaa atatataaaa cttaaaaatt taataaatga
    16501 cttatcttat gatgttgatg atagagagat tgtaaatctt tataaaaata tattagaaga
    16561 atttaatata acaaaagata taaaactcaa atactcttat gaagttgaaa caccagcatt
    16621 ttttaattca tgtgtacttt tgccaccaca tgagtataaa ttgaaagagt tagactggat
    16681 ttttagacat gagcttatgc attttaagag tagggacctt tatttaaaat atgtaatcct
    16741 gtttttaaaa acagtatatt ggtttaatcc atttatatat ataatggata aacatataga
    16801 tttagattgt gaactttatt gtgatgaaag agttttaaaa aatcgaaatt cagaggaaaa
    16861 aaaggattat gctttaacaa ttctaaatgc aatgagaaaa ggttcaaata cttcaaataa
    16921 atttatagct ggactccata agcaatctga tattaaaaag agagttatga atatgtttaa
    16981 tgaaaagtac aagaatggta tattaatggc attaacttta tgtttattat cttctattac
    17041 ttttttgaag gttaattcaa cgagtattgt taatcttaat gtattaccta aaggatttga
    17101 agacttacga actgttagca gtatacgttt ttcagttata ggatttacat atgcagatgc
    17161 tcctaaaaat atgagggaag aatataaaat aaattgtgaa tcattaggtt tgatacctaa
    17221 agactctgat aaaatagaag ttggtgtaga atattatgac agtctattga atgattaaat
    17281 aaatattatt ttaacagata ttaattataa agttttgaat agtaatttgt tgagaaataa
    17341 atatatcctt ataaaaatag atacttatat accaagaata aaaaatagtt aagatagtac
    17401 acaaggatat acttataaag aacttaaata agtgaaataa attattaatt ataaggttta
    17461 taattttaaa aaattagata aattcaggtg taaaatacta taaaacacaa ttcggaaaag
    17521 tgtatgttga acttcattta aaatagaatt ttcaaagttg ttatagtaag tagtttaagc
    17581 attcttctta tattaatctt tgagaataat gtacttaaaa aagttagtaa aaaatttaac
    17641 tattgtatat taatgatagt tgctattgat atattatcta aaaaaattaa gtatgaaaag
    17701 attactgcta ggacaatctt ttcatactta attttttaat atttatattc tccaaaattt
    17761 tcatcttttt aacttagaat tattagaatt tgagaatcac tattaggaaa taggttttga
    17821 tttatgcagg gttaaaaatt tcacagaata tctaacttta tactaaatcc atcaaaaaat
    17881 atacgccata taaaagcgca taaaaaaaca cataaaacaa tatttatgcg cactttaacc
    17941 tcgaatggta caaaattctt tacttttaca gacccatatt atataattaa gtaaataatg
    18001 tatatttagg tgacatattg gataagctaa tttatttatt ttattaatat aatgatacta
    18061 taaaagttat ataaagtggt ttacaaaaaa gttacagata gagcttttat taatgtattg
    18121 tgtattagta ttttatcctt aggtacactt cacctacaaa atagaatcat aagataatta
    18181 tgggaaaatt ttaggaggtt tatcgtgaag aaaaagatat taataccagt atttgcatca
    18241 gttatggcat tatcagtaag ttcaattgta aatgcagatg aagtaaatga ttcatctcaa
    18301 aataaggatg ataaaacaaa tactgaatta aatttaggtg aatataaaga agtaaaatat
    18361 aaagttgcaa aaataaaaga tggagtagct ataaagataa gagaagaagg tcaagttcaa
    18421 aacatagctt attctggaga tgaatttacg gttttaggaa ctcaaggaga atgggttaag
    18481 gttaaagttg aagatggcga aggttggtta gctactagat atgtagatat atctgaaggt
    18541 gtaggatata ctaacgctga taaagtaaac ttaagaaaag ataagagtga aagttcagaa
    18601 gtaattgaag agctggaaaa aggaagttct ttattggttt tggaggataa tggagattgg
    18661 ttaaaagtta aagatgggga aacagaagga tatgtaaaat catcttatat atctgataaa
    18721 gctcctgtaa tagaagagcc acaagtaaac ccaagtattg accaaaatgt agattctaca
    18781 aataataatc aacaaaacaa tgcaaatact aatcaacaaa ataataattc aaatgtgcca
    18841 acagctaact ctaatgcagt tcaagctgta cttaacttgg catattctaa gcaaggttgt
    18901 ccatatgttt ggggagcaga aggaccaaac acttttgact gttctggatt tacacaatat
    18961 gtgtatagaa atgcagtagg aaagaatata ccaagaacat ctaaagcaca atctaaatat
    19021 ggacaaactg taagtaaagc aaatttacaa ccaggagact tagtattctt cacaactaat
    19081 ggttctggtt ctgttagtca tgttggaata tatgtaggtg ggggtaatat gatacattca
    19141 ccatcaacag gaaaaacagt tagtgtaact agtataaatt catcatacta tacagcaaga
    19201 tttgttacag caaaaagaat attataatcg gtttgtaata tgacaaattg ataaatacat
    19261 aaatatatat aaacgctcta tattatattt aatttaatca tggaaacaaa aaatgattat
    19321 attttaaatg tactatagag cgtttttgta tcactttaaa tctaatcaag attcaagtta
    19381 atatgactat taaataggag ccttttcata tgatgattat ttgcgcaatc ccttgacagg
    19441 atagggtaaa ggtggtaagc tactaacagt acaaaaatac ttttaatttt agttcagaga
    19501 ggctaaaaaa ggaggacgaa agatgttaaa atcaagaaat ttaatccaac cagaagactt
    19561 ttcaatagaa gaaatagatg aaatattaga attagctcaa aaaataattg acaatccgtc
    19621 aaaatattct cgtatatgtg aaggaaaact attagctaca ttattttatg aaccatcaac
    19681 aagaacaaga ttaagctttg aatctgctat gaacagatta ggaggacgtg tagtaggctt
    19741 ttcagagcca aattcatcct ctgcatcaaa aggtgaaact ctaggagata caatgaggat
    19801 agtatctggt tatgttgata taatagctat gagacatcct caatcaggtg cagcttcaga
    19861 agcagctaga tatacggaag tgccatttat aaatgcagga gacggcaaaa accagcatcc
    19921 aactcaaaca cttacagact tacttactat aaaatcatta aaaggaactt tagaaagcca
    19981 tacaatagga ttatgtggtg atttaaaata tggaagaact gtgcattctt tggttaaggc
    20041 tatggcaaga tataaaaata caaagtttgt atttatagcg cctgaagagt taaaaatgcc
    20101 agattatata aaagaagcta taaagggaca tgcatattat gaaactaata atttggatga
    20161 tgttatagga agcttggatg ttttatatat gactagagtt caacaagaaa ggtttgaaga
    20221 taaatcagag tatgaaagac ttaaaaacta ttatatttta aataaagcta aattagaaaa
    20281 ggcatctaaa gatatgttag taatgcatcc attaccaaga gtaaatgaaa tagacataga
    20341 tgtagatagt gatgatagag ctgtatattt taaacaagct aaatatggaa tgtatgttag
    20401 aatggcttta ataataaaac ttttaggtat aaatgaagac taatagttat catataatag
    20461 taaaacaaag gagattttgg gatgtataaa attctggaaa atatatatat aggcgaagat
    20521 atgtatagaa tgaaagtaaa aggtaatttt gaaggtaaaa tgggacaatt ctatatgtta
    20581 agagcatggg atacttatcc agtactttca agacctataa gtatacatga tatagatgaa
    20641 gaagggataa cttttcttta taaagtagta ggagaaggaa ctcaaatttt gagtaaccta
    20701 aaggtaaatg ataatataaa attagaaggc ccttatggta atggatatgc taaggttgat
    20761 ggaaaggtag ctctagtagg aggaggaatc ggtgtagctc cactatattt ggttgctaaa
    20821 aatataaaaa attgtgatgc atatcttggg tttagagaag atgttatatt agaagatgaa
    20881 tataagcaag tatgtaataa agtctataca acagtaggaa atacttttgt aacagatata
    20941 attgatgttg agaaatatga ttatatatta acatgtggtc caactccaat gatggaaaaa
    21001 ttagttaaga tggtagaagg tactaaaacg agaattatgg tatctcttga aaaccatatg
    21061 gcttgtggag taggtgcctg tttagtatgt acgtgtaaaa ctaatggagg aaacaaaaag
    21121 acttgtaaag atggtccagt gttctgggga gaggacgtga tttttaatgg gtaatttaag
    21181 tgtgaaattt ggaagtgtag aatttaaaaa tccagtaata atggcgtctg gaacttttgg
    21241 atttggaaaa gaatataatg agatttatga tatacaaaaa cttggtggta taagtagcaa
    21301 gggtcttact ttaaataaaa aacctggtaa caatggtatg agagttcatg agacaccatc
    21361 cggtatgatg aatagtgttg ggcttgaaaa ccctggagtt caaggattta tagactatga
    21421 attacctttt tttagtaaac tagacttagt cagaatagct aatgttggag gtgggacatt
    21481 agaagactac ttattagggg ttcaaatgtt aaatgacaag cctatagaca ttattgaatt
    21541 aaatatatct tgcccaaatg tcaaagctgg tggaatggct tttggtataa aaaatgaagt
    21601 ggcaagagaa gttgttcgtg aggtaagaaa cataacgaaa ctgcctttag taataaaatt
    21661 atcacccaat gcagaagata ttgtaggaat ggcaaaagtt tgtgaagaag aaggtgctga
    21721 tggagtttca ttagttaata cttttaaagc aatggcaatt gatataaaaa atagaagacc
    21781 agtatttgaa aatgtatatg ctggattatc tggaccagct ataaaaccta tagctttgag
    21841 aatggtacat gaagtgtgta aaaatgtaaa tatacctgta atgggaatgg gcggaataac
    21901 taaagccaca gatgctatag agtttataat ggcaggagct acttgtatcc aagttggaac
    21961 tgcaaatttt atgaatccta gaataggtat tgaaataata gatgggatta atgaatttat
    22021 ggatagagaa ggaataaaaa gtttagacga aataagagga attatataag gtagaataaa
    22081 tagtatttta aagataaaaa atatagatta aataaacaat aattttataa cattaacatg
    22141 gaggaaaaat aatatgagta aagtagatgt agtggatata ttaaagaaaa gtgatgcatt
    22201 gttggaggga cattttttat tatcttcagg aaaacacagt aatagatacg tacaatgtgc
    22261 aaaagtatta agatttccag aatatgctgc tgaggtatta agtacagttg ttgaacaaat
    22321 aaaagactta gatatagact tagtagtagg accagctatg ggtggagtaa tagtttctta
    22381 tgagttagga agacaattag gaaaagaagc tgtatttact gagagaaaag acaatacaat
    22441 ggagttaaga agaggatttg aagttaaaaa aggagcaaag ataataattg ctgaagacgt
    22501 tgtaactact ggtaaatcaa ctatggagac aaaaagagta ttagaagcct taggtggaga
    22561 agttgtaggt gttgcatgta tagcagatag aactaatcat gatataggta tgcctatata
    22621 tagtgctata aaacttgata ttcaagttta tgaatctgat gagtgtcctt tatgtaagga
    22681 aggaaaatta ccagttgtta agcctggaag tagagagttc aaggaattag ggatgtaata
    22741 aaaacttaat tatttatagt gttacttaaa aaatgtaaat tttttagagt aaaaatttgt
    22801 aatataacat ataacttaaa aataaaaagc agttagcctt ataaatgaag gttagctgtt
    22861 ttttttgtta aaaatatatt tacaaaataa gagatagtag cagtacaata taagtataag
    22921 gtaaaagtat tatatattag ggaggggtaa gtatgaaaaa tcaattaaat gaaaatcata
    22981 aaaaggttgt attttttgga gtaggtgctg taggagctac ttttgcagaa caatttttta
    23041 actctaaata tgattttaaa attctttgtg ataatgaaag aaagaaaaga tatttagaag
    23101 aaggatttat aataaatgga aaaaggtatg attttaatta tgtaactaaa gatgagtata
    23161 aacaagaggc tgattttata attataggtc taaaatataa taatttaaaa gaaaatataa
    23221 aagaattaga tggattagtt ggaaaaaata cagttataat gtctctgcta aatggagttg
    23281 atagcgaaga gataatagga gaaagatttg gaattggaaa aatggtatat tcatatgtta
    23341 ccaatataga tgcaaagaaa atcaataata atattataca cactactaat gggataattg
    23401 tatttggtaa caaagataat agtgaagata gaaaaactaa tataataact gaagtctttg
    23461 atgatgtaaa tatagaatat attttatcaa aagatattca acgagatatg tggtggaagt
    23521 acatggttaa tattggtgta aatcaaactt cagctatact tggtgcacct tatggagttt
    23581 ttcagagttc tgagcattta agagaattag caaaatctgc aatgagggaa gttgttgcta
    23641 tagcacaagc aaaagacata tctcttacag aagatgatgt tgaaaattca ttacatagaa
    23701 tactagaaca ttcaaaagaa ggaagaacat caatgcttca agacgtggaa gctcatagac
    23761 ctacagaagt agatatgttt tctaagaata tctgcaaact tggaaaaaaa tatagcatac
    23821 ctactcctat aaatcagact ttattttata tgataaaagt aattgaaagt agattttaaa
    23881 gggtatttgt aagaaatatt gataattatt gattttaaat tttattaatg ttatatacta
    23941 tttaagttac taaatatttt taactcttca atgaaaatag ttgctgcttt tgacaaagtt
    24001 atatcttttg gaaatatata tgagaaatgt ctgttgtagc tgcttccaag ctctatgaca
    24061 gacagctcat tgtttaaaac aggtaagctt gtcactagat tagaaactat tgtaattcct
    24121 aaattatttc taacagattc tttgacagca taattacttc caaaaaccat catacttttt
    24181 ggaataattt ctttaacact taaaaacata tctaaatagt ctctggttcc agaaccatcc
    24241 tccctgacta tccatttttg gtcttgaagt ttatcaaaac taaaatcttt taataaatga
    24301 ctattgtatg gaagtgctaa aaccatctta tcttcaaaaa aatattcttg aataaatgaa
    24361 ggggaagagc aagtgccttc aataagacca atgtctaaaa tataatcctt aacatgagaa
    24421 gatacgattg atgtattttt tataaaaact tctacatata tgtcaggata cttttgagaa
    24481 aataatgcta aaaaatttgg tagaatatat tctccaatag ttaaacttgc accaatcttt
    24541 aagtgaccag ttatagcatc tgaaacttgg cttacatcat gataagtaat atttaaaaga
    24601 tttaatattt ctttagctct tttgtacaat atttgtccac tttctgttat aaaaatggtt
    24661 ttttgtttaa tagacctgtt tataagcaca actttaaaat aattctctag attttttatg
    24721 tgtttactta cacttggttg tgatagattt aagtattccc cagctttagt aaagtttttg
    24781 tattcaacaa cagctacaaa tgtttttaat tcttcaaaca attttttgtc tccttcacct
    24841 aatgaaattt tacatttttt atatactttc tacagataat tatactatat ataataacca
    24901 ttaaaaacat taatcattac gatattatat atttatttta cttatggtta ttacaattat
    24961 atactattgc tatgaagaaa actatattaa ttataaggta ggtatattat gttaaagaaa
    25021 aaaagcagtt tgacattaaa aactataagg gaaatattac caggactgtt tatatcagtg
    25081 ttagtaggtt atattagtat atttatttct attttaattc ctaaggtagg ggcagcatca
    25141 atttctatat ttttaggtat gtttgtagga aacctatttt taaatcaaaa ggtatttcaa
    25201 aaaggttata aattttcaga gacagatttg ttatcatatt caatagtact attaggggca
    25261 acactcagtg tatctacctt aatagactta aaagtttcag gaattttatt tataatattg
    25321 caaatgacaa taacaataat agctgcactt tatataggta aaaaactagg atttgaagaa
    25381 aactttagat ttctaatggc aagtggaaat gcagtatgtg gttcttctgc cataggagca
    25441 atagttccag tggttaatgc gacagataaa gaaaagggaa ttgcagtaac tattgtaaat
    25501 gttactggta tattccttat gtttttactt ccaataatat ctcaattttt atatagccat
    25561 gaacttgtaa aaacttcagc aatgataggt ggaactttgc aatcaattgg tcaggttgta
    25621 gcaagtggag caattgttgg agaaaatgta aaagatttgg ctactatttt taagatagta
    25681 agagtaatat ttctagttgt tgttgtatta gtatttggac atatgaaaaa tcagtctaat
    25741 agggaaatcc ttgaagaaga aaaggatgag ataaaaaaga aaaaagtaac tataccatgg
    25801 tatgtaattg gattctttat aacttgtgca cttttttcaa tgaacattat accaaaagaa
    25861 gtatctgtgt tgtgcaaaga aataagtaac aaactagaaa taatagcttt agcagcaatt
    25921 ggattaaaag ttaatgtaaa agatttagtg aaacaaggga aagaagtttc tttatatggt
    25981 ttatttgtag gtacagtaca agttgtatca gctgtagttt taataaaaat atttatatag
    26041 cacaaaaata gtatttgtaa tattaatttg attaattaaa ataatatgat actaataatt
    26101 tataatataa ataaaaaatg aatttcgata agtttaagtg ggtataaact tatagaaatt
    26161 cattttttat ttaaggtaaa aatttaaagt aaaatattat tttacataat aataacctta
    26221 taaattttga aattacttat ctttgtgtta aaataagtaa aatacacata ttaaagttaa
    26281 gtttttaggc aaataaacaa aatgaaaata taaatattaa ggagatttgg tatatgaatg
    26341 tttatgaaaa aggtaatgga gttatactag aaggagtaac agattttgac ccagtacata
    26401 tatttgagtg tggtcaatgt tttagatggc acaaacaaga agatggctca tacactggag
    26461 ttgcaagggg gagaatatta aatgtcaaaa aagagaatga taaaatatat ttaaataata
    26521 cgaatttaaa ggagtttaac agcatttggt ataattactt tgatttagga actgattata
    26581 cagaaataaa gaataagcta aaaaatatgg atgaatattt gaataaggct actgaatttg
    26641 gatggggaat aagaatatta agacaagatg gatgggaaat gcttatatca tttataattt
    26701 cctctaataa tagaattcct atgatacaaa gagcgataga aaatttatca agaaagtttg
    26761 gtaagtatat aggtgaatat gaaggtaatg aatactatgc attcccaaca ccagaagaac
    26821 taaataaggc ctcacaagag gaaataagag catgtcaaac aggttttaga gataagtaca
    26881 taaaaagtac tacacaggca gttatagaga ataatgatga ggtatctgaa tatacaaatt
    26941 taagtacaga ggattgtaga aaagagcttt taaaatttaa tggagtagga ccaaaagtat
    27001 gtgattgtat tgcattattt ggtatgcaaa aatatgattc ttttccagtt gatgtttggg
    27061 ttaagagagt tatgcaagaa ttttatatag atgaagacat gagtttacct aaaatgagaa
    27121 cttatggaat cgataaattt aaagaaatgt ctggatttgc tcaacagtac ttattttact
    27181 atgcaagaga actcggtata ggaaaataaa ttaaggggga gaaattatgg gagtaatagg
    27241 aacaatattt ctgttctatt taattatatc atatctagct ggagccataa tttctgtgat
    27301 tatattgctt gaaaatagag accctgcaaa aacaatgtct tggctattga tgtttattat
    27361 atttccaggt gtaggtttaa tgatatatgc tatttcaggt agaaatatta gaaaaagaaa
    27421 attatttaag actcaaaaac tagctaataa tataaaagaa aagaaactat ttgatacatt
    27481 agaaaagata acagaaatag ttgaattaga aaaagaatct ataaaacaaa ataagctttt
    27541 aagagatgaa gaggatggta gttatagaaa aagggtaata aatatgttgt taaagactgg
    27601 tatgtttccc tttactaaaa ataataaagt ggatgtattt gtagatggaa atgaaaagtt
    27661 taaaagactt atagaagata taagagaagc taaagaccat attcatttag agtactttat
    27721 catcaaagat agtgaaatag gtagggtgtt aaaagaagaa cttataaaaa aggctaaaga
    27781 aggcattaag ataagaattt tatatgatga tgtaggatgc tggagatttt ggtttaatag
    27841 aaaatttttc cgagaaatga gggaagtagg tatagaaatt gcagcatttt tacctacaaa
    27901 atttcctata ataggaggga aattaaacta tagaaatcac agaaaaattg ttgttattga
    27961 tggaataatt ggatatacag gtggaataaa tataggagat gaatatttag gcaaaaatga
    28021 taagtttgga tattggagag atactcatat taggattaag ggtatttctg tatacatgct
    28081 tcaaatgaca tttctgattg attggtatta tacgacaaaa gaagtattag tgactaaaaa
    28141 ttatttccca agtgtaggga atgttggtga aagtatgata caagttgttg cgagtggtcc
    28201 agacagtgac tgggaagata ttcattatgc ttatttttct gcaatatgtc aggctagaaa
    28261 aaatgtttat atagaaactc catattttat tccagatgaa agtctactaa aagctataaa
    28321 gagtgctgct cttagtggag ttgatgtgag aataatattt cctaaaattg cagaccacaa
    28381 gatagtaaat atagcatctt attcatattt tgaagaaata ttaagagcag gtggtaaagt
    28441 ttatttatat aataaaggat ttatacattc taaagtcgta ataatagatg ataaaattgc
    28501 ttctgcaggt acagctaata tggatttaag aagttttatg cttaactttg aggtaaatgc
    28561 atttatctat gatgaagaag ttattagggt aatgacagat gatttctttg aggatttaag
    28621 tcactgtgaa gaacttaatt tggaggtatt taagaataga aatatcatac aaaaaatcaa
    28681 agaatctgta gcaagattat tttcaccaat attataaaaa attattaaaa aaggtattga
    28741 aaattatgtg tgattggtat attataataa ttgttagcac tctattagat agagtgataa
    28801 taaataaaaa gtatatatat aaatctacat atataagtag tattaattta aaaataacta
    28861 aaaacatagg cgaactagtc tatacttaat attttaggag gcgtgaataa tgaaaataag
    28921 accattagct gacagagtag taattaaaaa agtagaagca gaagaaaaaa ctgcaagtgg
    28981 aatagtttta ccaggagcag ctaaagagca acctcaaata gctgaagttg tagaagttgg
    29041 accaggtgga atagttgaag ggaaagaaat aaaaatggaa ttgacagtgg gagataaggt
    29101 tatattccaa aaatattctg gaacagaagt taagatagaa ggacaagaat acacaatact
    29161 aagacagagt gatgtattag ctgttattga ataaatatag aataaattta ttaggaggga
    29221 tttaaaatgg ctaaagaaat taaattttca gaggaaacaa gaagagcttt agaagctggt
    29281 gtaaataaat tagcagatac agtaaaagta acattaggac ctaaaggaag aaatgttata
    29341 ttagataaaa aatttggttc tccacttata actaatgatg gagtaactat agcaaaagag
    29401 atagaactag aagatagatt tgaaaatatg ggtgctcaat tagttaaaga agtagcaact
    29461 aaaactaatg atgtagctgg agatggtact acaactgcta cagttttagc acaagctata
    29521 ataagagaag gtttaaagaa tgtaacagca ggggctaacc caatactttt aagaaaagga
    29581 atacaaaaag cagtaatagt agcggtagaa gaattaaaaa atcaatcaag aatagtagaa
    29641 acacaagagg ctatatctca agttgcttct atatctgctg gtgatgaaga agttggaaaa
    29701 ttaatagcag aagctatgga aatagtaggt aaagatggag ttataactgt tgaagagtct
    29761 caaactatga atactgaatt agatgctgtt gaaggtatgc agtttgatag aggatttgtt
    29821 tctgcatata tggttacaga tgtagataaa atggaagcag ttttaaatga cccatatata
    29881 ttaattactg ataagaaaat atctaacata caagaattat taccagttct tgaacaaata
    29941 gttcaacaag gtaaaaagtt attgataata gctgaagatg tagaaggtga agcattatct
    30001 acattagtag taaataaatt aagaggaaca tttgatgtag tagcagttaa agctccaggc
    30061 tttggagata gaagaaaaga aatgcttcaa gatatagcaa tacttacagg tgctcaagta
    30121 atatcagaag aattaggtta tgatttaaaa gaagctgatt tatctatgct aggtagagct
    30181 tcatctgtta aggtaactaa agaaagtact acaatagtag atggttctgg agataaaaaa
    30241 gctatagaag atagagtaac tcaaattaaa catcaagtag agcaaactac ttcagatttt
    30301 gatagagaga aattaatgga aagattagct aaacttgctg gaggagtagc tgttgtaaaa
    30361 gttggagctg ctacagaagt agagttaaaa gaaagaaaat taagaataga agatgctctt
    30421 aatgcaacta gagcagctgt agaagaagga atagtagctg gtggaggaac tgcttttgtt
    30481 agtgttatac cagcaatagg aacactaatt gagagtttag aaggagaagt taaactaggt
    30541 gctcaaatag ttaaaaaagc gttagaagag ccattaagac aaatagctat aaatgctggt
    30601 cttgaaggtg ctgtaattgt gcaaaatgtt gttaattctg aagcagaaac tggatttgac
    30661 gcattgaatg aaaaatatgt aaatatgata gaagctggta tagttgaccc aactaaagtt
    30721 agtagaagtg ctttacaaaa tgctgcatca atagcaagta ctttcttaac tactgaagct
    30781 gctgttgctg accttcctga aaaagaagat gcaggaatgc caggaatggg tggcggaatg
    30841 cctggtatga tgtaatttaa aaaatttaaa atataaattt taatataaag aactatttcg
    30901 acttagattt taaactctaa gttgaaatag ttcttttgta tatatctaat ttttgtatat
    30961 ctataaattc aatacacata tttagataat cagtatctag tttgtaataa tattttagag
    31021 tagtattgtt attttttagg ttatgatttt agatatatat taattaaggt ataattgttg
    31081 atagagaata aatcaaattt aaaaggatgc gataatatgg acttaagaaa attacttgaa
    31141 gaagttaaaa atgaaaatat tgatatagat tttgcgttag aaaagttaaa agatttacct
    31201 tatgaagacc ttggatatgc aaatatagac catcatagag aattaagaaa tgggtatccg
    31261 gaagttattt attgtgaagg taagagtgat gagcatattt tagggattat tgataaaatg
    31321 aatcaaaaaa gttctaacat attggggaca aggtgcagaa aagaaacttt tctgaaaatt
    31381 aaagaaatct ataatcatgc tgagtacgaa gaggcgtcta aaattcttaa gattcaaaat
    31441 catgatatag agaatatagg aaaaggtaaa attgtgattg ctacaggggg aacttctgat
    31501 ataccagtag cagacgaagc ttatcataca gctaagtttt taggtaatga tgttgataga
    31561 atatatgatg ttggagtggc aggtatacat aggcttttaa ataaaagaca taaaatagat
    31621 agtgctagag taatagtagc cgttgcaggt atggaaggtg ctcttgcaag tgtaattggt
    31681 ggactggttg atgttccagt aatagctgtt ccaacttctg ttggatatgg agcaaatttt
    31741 ggaggattag cagcattact agctatgtta aatagctgtg catctggaat atctgttgta
    31801 aatattgata atggatttgg agcaggatat ttagcatcaa tgataaataa actgtaaata
    31861 cattgatata aattaaacaa aactatataa taaaatttaa tttctattat atttttacta
    31921 ttaaaattga ggagacatat atgagtgaaa aaatacttta ttttgatata ataagcggta
    31981 tatcagggga tatgaccctt gcaagtttat taaatttagg tgtgcctaag gaaatttttt
    32041 tggaggaaat tcataaacta agaatgagcg atgaatttaa tataaacatc agctcgaaaa
    32101 ctgaaaatgg aatagtaggt acaaaagtag aagtaattac aaaagaaaaa catacacata
    32161 gaaatttagt ggatatattt gaggttatag ataaaagcac tctaaacgaa aatgtaaaat
    32221 ctaaagcaaa aaaaatattt atggtaattg gagaagcaga agcaaaagtt catggaacta
    32281 caatagacaa gatacatttt catgaggtag gggctataga ttcaattgta gatatagtag
    32341 gagcttctat attagttgac ttactttgtg tagataaagt ttgtgctagt acagtgtctg
    32401 ttggttcagg atttgtaaaa tgtgaacatg gaattatacc tatacctgca cctgcaacta
    32461 tagaaatttt aaaaggtgtg ccaattaaat taaataatgt aaatggagaa tgtacaactc
    32521 caacaggagc tgcaatcata aaagtcttgt gtgatgagtt tgtagatgag cttgaatttt
    32581 ctccaaagca aattggatat ggtataggtc ataagaagtt tgaagtacca aatatactca
    32641 gaactgtatt aggtgaaaaa aaaaagaaga attaatttat gaaattagtg caaacattga
    32701 tgatatgtct tcagaaatct attcttattt gtatgaaaaa atattagatg agaaagcatt
    32761 ggatatttat acagagagta tttatatgaa gaagaataga ccagcaacaa aagtatcaat
    32821 tttatgtaat gaatcagatt tagaaaagtt tattaaaata ttacttttag aaactagtac
    32881 ttttggagtg agatataatg catataatag agaaatttta gagagaaaat ttgtaaaatt
    32941 agatacaaaa tatggagtgg ttacagtaaa actagggtat tataaaggaa aactagtcaa
    33001 ggttactcca gaatataatg aatgtaaaac tatagcaaaa aatgaagata ttcctataaa
    33061 aaaagtgttt gctgatataa attttagaat aaaagaagaa tttagtgaaa acttattgac
    33121 ataagtaata aattttgata aattaatatt cagccttatt aaataaaagt aaacagaaaa
    33181 aaatatataa aatataaact cactcgtata tgctcagaaa tatggtctga gagtctctac
    33241 caagataccg taaatatctt gactatgagt gaaattatta taccaaaaga cctagttaag
    33301 taaatgtgta ggctgagtta tactccctat gtgttggcta taagataaag gtattttgga
    33361 agcctgtata gtaatttcac ttttgctaga aattatggaa gttactatac aggttttttg
    33421 tgtaaaaaga tttaatataa tttagactgt attgtgttaa aataaatata taaaaactat
    33481 attatacaag gagagatgtg aatttatgaa acatgaatta gtacttgtaa tagattttgg
    33541 aggacaatat aatcagttga tagctagaag agttagagaa aacaacgtat attgtgaaat
    33601 acttccatgt actgcaagca tagaaagaat aaaagaaaaa aatcctaaag ggataatatt
    33661 tacaggcggt ccaaatagtg cgtatttaga agattctcca acaatatcaa aagaaatatt
    33721 tgaactagga gtaccaatac ttggaatatg ctatggtatt caaataatgt ctcatgtatt
    33781 gggtggagtt gtaagaaaag gtaataaaca agaaaaggaa tatggaaaaa catctataac
    33841 ttatggaaaa tcatcattat ttgaaggaat aactacaaat agtgtatgga tgagtcatac
    33901 agatttaata gaaaaagttc cagaaggatt tactatagtt gcaaatacta atgattgtcc
    33961 agtagcagct atggaaaatg tagaacgaaa cctatatgga gttcaattcc atccagaggt
    34021 agaacactgt ttggaagggg acaagatact tacaaacttc ttatataata tttgtaaagt
    34081 aaaaggtgac tggactacag attcattcat agaagataaa ataaaagaat taaaagaaaa
    34141 aataggcgat aaaaaagctt tatgtgcttt aagtggagga gttgattctt ctgttgctgc
    34201 agttcttatt cataaagcaa ttggggacaa cttaacttgt atatttgttg accatggttt
    34261 acttagaaaa aatgaaggaa atgatgtaga aagaatattt agagagaaat ttgatataaa
    34321 tttaataaga gttaatgcag aagatagatt cttatctaaa ttaaaaggag tttccgaacc
    34381 agaagctaag agaaaaataa taggtgaaga atttataaga gtatttgaag aagaatcaaa
    34441 taaattagga aaaatggatt tcttagtaca aggaacaatc tatccagatg ttatagaaag
    34501 tggacatgga aatgctgcta ctataaagtc tcatcataat gttggtggaa tcccagaaga
    34561 tgtagacttc caagaaattg tagaaccatt aagagagtta tttaaggatg aagttagaaa
    34621 aataggatta gagcttggta tagaagaagg attaatattt agacatcctt tcccaggacc
    34681 aggtctagga ataagagtta taggtgatgt aactaaagaa aaatgtgata tattaagaga
    34741 agctgatgct gtttatatgg acgagcttag aaaagcaggt ttatacagag aaatatggca
    34801 agcttttgca acattaccag atgttaagac tgttggagtc atgggtgatg aaagaacata
    34861 tgcttattta gttggtttaa gagcagttac ttcttctgat ggaatgactt ctgactggta
    34921 taagatgcct tatgatgtat tagaaagaat ttctaataga ataataaatg aagttgatgg
    34981 agtaaataga gtagtttatg atataacttc taaacctcct ggaactattg aatgggaata
    35041 aaatatagaa tgccagaaat ccacatgaat acaggatttg aggtctctct tacttctata
    35101 ttatactggt ttgatactat caatatttgc cagtatctta tggattaata agcaaaaaac
    35161 atcctgctga atggtaaatt cggcggggtg tttttatttt gttttgaaac tcctttgctc
    35221 tgaaactcga agtatttaac actgatgatg ttgttatctt ttagttcctt ttgtgtcatg
    35281 ctctgaaaga caaattgata caataaaaaa gtaatttctt aatcattgat ggagatatgt
    35341 atttatgtta ctcttgatgg taatttgagt aatattgttc atagcttttt atattcactt
    35401 aattagaaaa ccatttggta taatcataaa taaacttgat gatataatag aaaagattta
    35461 taattattag aagtatataa aagtatttta tgtctatgaa atgtatgtct ataaaacata
    35521 tagatgactt ttgtatatta atgtatgaat attgatatta tagaagaatt gagttgtcaa
    35581 tgatactaaa tcaaatattt atagaagatg gagggattat gagaaataaa ataattatag
    35641 gaattacttt ttcacttgta ttactaatgt ctggatgtgc ttcaaaacaa acagcagaaa
    35701 taaacgtatt agcaactact gatttacatg gagttatacc ttatgagtta acttcttatg
    35761 taaaagaaga aagaaaaaaa gataaaaatc taactttagt agatgcagga gatttttttg
    35821 atagtggaga agtgtttggt tctagcatgg atagttattt tagtgctaga tataaagatg
    35881 gtgataataa cactgaaagt tatattgaga cgcctatttc aaaagatatg aaagaggtag
    35941 gttatgatgt tgcagttctt gggaatcatg aatttatatc caacaataaa ttttatctag
    36001 ataatatgat atctgatttt gagaaacaaa aaataaatat tttatcggca aatacgtata
    36061 aaaaaaatgg agatagttat acaaaaccat acataataaa aaatattaat acacctgaag
    36121 gaaacgtaaa actaggaatt ttagggctta ctataaaaga agttggtgag aggaaacagt
    36181 ggaaagatgg aaaacttgtt gactctaagt ctttagaact aaaagaccaa gagggctaca
    36241 atggtgaatt gtatatgaat gatttagtag aagatgctaa aaagtgggtt ggtataatgg
    36301 aaaaagagaa gcctgacatt atagttgctg tggcacatac aggtgagaaa cctaagaaac
    36361 ctagaaaccc aggaaataga atacaagact tagctcaaca agttgatgga attgatgcta
    36421 tagttgcagg tcataatcat gttcaaattg agcaacatga ttataaaaat aaatcaggag
    36481 aaaatgttat agttactgag ccaggaaagc atggggaata tatttctaag attaatttta
    36541 aattagaaaa aaacaatgat aaatggaata tagttgacaa atctagtaaa ttaattaaat
    36601 ttgaaaaaaa tcaagaaagt gataaatttg gagaatttat ttcttcaatt aataaagtaa
    36661 gtaaagataa gaaagaaata agattatcag aagtaaagac tcctgaatgg gataaaatat
    36721 atgtttttaa atctggaaca tctgcagatg atatatataa aacaatagga tataaatgga
    36781 gaaatatatc atctccaaag ggtgatgaca tggtgcagat tgttgtaatg aataataata
    36841 agcctgttag ctatatatat ggtgaagctg aagttatgcc aattaatata aaatgtgatg
    36901 aatcagagta taaaaataat gttgtaacta tttatcctaa taaaaatgat aaatttaaaa
    36961 ttgaaaaagg taagcaagaa tatagtatta atttaaaaca tatacaatag aaacttttat
    37021 cttatttaag tttagattgt acttaaaata aagtgtgtat tattttaaaa agtgatgata
    37081 attaaaatca caacattaag gaatagtaca cactttttat gctaaaaaat agaatgttaa
    37141 aaaattaaac ctttaaatta aagtacattg cttatattat ccaatattat ttccaaaggt
    37201 tgtgtaatat ttttatcctt atgtaatatt gctaacattt tattttccat atctatctca
    37261 tctaattcaa tcaatcgcaa ttttttatgt aagagtgaat ctaataataa attttctggc
    37321 aaaatggtta tacctaaccc tgcttctgca gctttaataa gtgcaaaaga attaacactt
    37381 tcccaaacag gataagcttt ttggtttgaa agagataata cactgtccaa agtatcgcga
    37441 atagcacttc cttgttcacg taacaataac ggaaacgtgc ataactgtcg tagagataag
    37501 gtttgttcag ataaaggaaa agttggagca catgcaacac ataacttata ggaacctaat
    37561 aaaattgtac ggaatgcccc ctgtggttct ataccttccc aaaaacatat atcagcttct
    37621 ccacttttta aaatatccat agctgaatta gcactttcga cacgtacatt cactttaaga
    37681 gatggaaatg aattttttag tcgacttaaa attggtggaa gtaaaaaaga ggcaattgta
    37741 atgctagaaa caatgtttat aggtgtacat tcttctaaac gactgatttt tttgtctaaa
    37801 ttgcgacaag cagttaagat actacgtgct tcatctaaaa gagaaatgcc acagcgagta
    37861 agacataccc ctcgtggtaa tctgtcaaat agtgatgttt cagcttgttg ttcaagttca
    37921 gctatagcat gagatacagc agattgtgtg atatgtaatt tttttgcagc acctgtaaaa
    37981 gtgcctgttt gttcaattgc ttctaaaatc tctaaatatc gtatgtttat cataataaat
    38041 atcctcacta tacatgaata aaattaatta attccattaa attctatcat tttacagatt
    38101 gcaaagcaac aggtatactg aataatatga agtgaaaaga aggaggaata ttttgaatca
    38161 aagcagaaaa atatattttt ggcttttaat tattaacttg tttattagca cattcacttt
    38221 tggcggaggg tatgtagttg tacctatgat tagacgttat tttgtaaatc aaaagcaatt
    38281 ctttacagaa gatgatttga tgagtatggc agcagttgca caatcaactc ctggagctat
    38341 tgcaattaat ttatctgctt tggcaggtta tcgagtagct ggtactttag gggttgtcat
    38401 tagttgtaca gcagctataa tacctccact cgttattctt ggattagtat cagcatttta
    38461 caccactttt atatctaatg ccattgtaac tgcagtatta aaaggaatgc aagctggtgt
    38521 tgctgcacta attgtggatt tgattattga catgtgctct atgatattaa aacaacgttc
    38581 tttgttttta tcaactatga tacctattgc tttctttgca aactttgtga tgagtataaa
    38641 tgtaattttt atattatctg tttgctgttt tgtatgtgta atgcaagttt tctataagaa
    38701 gagggaaaat aaatgaatac aatttggaac ttatttttta tatttttaaa aataggcttg
    38761 tttagtattg gtggtggtta tgcaatcata cctttaatcc aagagaaagt agtaaatcaa
    38821 actggatgga taagtgagaa aatgtttaca gatattataa ctatttcaca aatgacacca
    38881 gggccactgg ctgttaatac ttctactttt gttggacttc aaattggagg gttttgggga
    38941 gcagttgcag ccactttagg ttgtgtatta tgtggtgtag taatatctct atttttatat
    39001 aatttttttc aaaagcatca gaactctact tatatatttg aaatattaaa tggtctaaaa
    39061 tcagcttcat taggtttaat tatctcagct gcggctacaa ttataatcct tgcattattt
    39121 gggacgaata aagtgtactt caattctata tttgagatgc taaactggac tgcactaata
    39181 atcttttttg ttatactact gatagtacgt aagtggaaaa ttaatcctat tgtgattata
    39241 ataataagtg gtatactagg aatatttttt tatttataag tttttggtaa gtaaaggata
    39301 tctatttttt tatatcttaa atccaaatag ccaataaagt aaggctattt ggatttttaa
    39361 taaattctga aaagataatc agaaacccat ataacattta aattatatca ctggttttct
    39421 acaaaccaat cataagcttc ttggcaaaat ttctcactat ctatatagta actattatga
    39481 acattattaa tttcaacaag tttcttttta cattttagtg aattataata gctatcaaaa
    39541 tattgggttt taaaatatct atcatgaagt gttttaaaga caagagtagg tatgttgact
    39601 ccatctttta tcttactatc ttctgcaata aagcattcta acattgtatt aattatcttt
    39661 gtactatttt tccaaatatg aggatttttc ttttcaaata ttttataaaa ttcattatca
    39721 tagacttcat tataaccttt atatttaggt ggttttactg ttatgtgaaa attaggaaga
    39781 aacttaaaga aaaaatataa taatttttat gttctgtttt atatattatt catattttat
    39841 cacagataat atactaaagt taattttttt attgtacaac tattataata attcttctat
    39901 aatataagac attctataat tttatattta agttcatgtg tatttaattg tttttatata
    39961 aaatgtccag taatactatt tggatttatt tttatttcat caggagttcc agaagcaaca
    40021 atttcccctc catttattcc actgtctgga cctatatcga taatccaatc agaagcacgt
    40081 ataacctctg tattgtgttc aataattaaa agtgaatgct gttcatttac aagttttcta
    40141 aaagtaatca acaaattttc tatatcttta aaatgaagtc cagtagtagg ctcatccaat
    40201 atgtacagca ttcgtttttt agtttttgtc cctaattctt ttgctaattt tatcctttga
    40261 gactctcctc cgcttaatcc taatgtattt tgtccaagct ttagatatcc aagtcccact
    40321 tcatctaata aggagagttt tctatatata tcagagcaat cactaaaaaa tgtttttgct
    40381 tctgctactt ccatgtcaag tatatctgca attgtttttc ccttgtattg tatagacagt
    40441 atttcttttt gatatctctt accttgacat tcattacaag ttacccattg gtctgccata
    40501 tattgtagaa taatttttgt tttacctaat ccttgacagt ttgggcattg cccctttttg
    40561 ctattaaagc taaaatagct ttcatccaat aatttttgtt ttgcttgtgg agtttcagta
    40621 aatagagaac gaatttcatc aaaaatattg atatatgtag caggtgtaga acggctagat
    40681 tttccaatag gtgtttggtc cattaagata aaatcgtcaa tagcatcaaa tccagtaagt
    40741 gcagtataat ttttatttgg gatagatttt tgtttcaatt tttcttctag agcaggaagt
    40801 aaactgtgaa atacaagaga actcttacca gaaccactaa cacctgtaat agagcacata
    40861 cagtttaagg gaatttctac atcaatattt tttaagttat ttgcatggca tccctttaag
    40921 cttaaccatt tacttggtat aattttattt tgtgaactta tcttattgta tgtactcaaa
    40981 tatttgcctg ttatagaatt tggatttttt ataatttctt gggttgtacc ttctgcaatg
    41041 atgaagcccc cttttgtacc agcatttggt cctacatcaa taatataatc agcagacagt
    41101 attgtatcct tatcatgttc cactactata acagtattac ccttgtctct taattcttct
    41161 atcattttga tgattagatt atggtctctt ggatgtaaac caatagatgg ttcgtctaaa
    41221 atataggtta atcctactaa ttcacttcct agctgacttg ataatcgtac tctctgcagt
    41281 tctcctccag ataaagttgg agctgttcta tctgttgata tatagctaag acctaccttt
    41341 aatagataac taactcgaat ttttaattct gttaagatat catttaccaa agatagctca
    41401 tttttttgaa gttgatttgg taattcacac aaccaattcc ataactgttc tatcgtcatt
    41461 tttgttagtt cagggaagcg ataacctttg attgtagtga atctagcctc aatgcacagc
    41521 aattcgccac cacatgtatt gcaaggaatt ttgttcatat attgatgcaa ggtattattt
    41581 tcagaactag attctctaaa aagtctttga atgtggttga ttgctcctga agcaggcctt
    41641 ctaatctttg attctcgtcc ctttgattca aagctaaatt catatatctt atcgtctgta
    41701 ccatataaga ttgcatctat aaaatctctt ggcaattcat tccaaggtat atctaggtct
    41761 atatttttat cttttgctat tgcatataat tcacctacca tccaattacc atttggcttt
    41821 ttccccctca attttccaaa atagtaagta gctccatcta atattgaaat agttgggtct
    41881 tttacaatta attgaggatt aacttgatag gtaaaaccca atccattaca atcgtgacaa
    41941 gctccagtat gggagttagc attgaaggtt gaagtattta tcttagaaaa aatagtttgg
    42001 caatgtggac aataattttt tgtattattc tttttttcta atggagtttt gcaatatgga
    42061 cagtaacttt ttccgattga tacaaataac attcttaagt aatcccaaat gcttgtaaga
    42121 gtaccaacag tagaacgagg attttggctt ccttttttct gttcgatagc tatagtaggg
    42181 gttaatccct gaagtaaatc aaattccggt ttttgaagct gttctgaaag ttttgctcca
    42241 ttacctagat tttcaaaata acgtcttttt ccttcttcat aaatcgtatc gaaagctaaa
    42301 gaagattttc cactaccact tacacctgta ataacagtta tttgattttt tggaattgta
    42361 acctcaacat cctttaaatt gttttgcctt cctcctttta gatagataga gcttttatta
    42421 tgacaaagtg aatttttaat tgatttattt attgcttttg caaatttgaa tttcttttct
    42481 agttcaagag gattgcctaa ttcttttatt tccgaaatac ctaatatttt taactgagaa
    42541 aagattgatt tcaaataatc ttcaggcaat ttttctatta acaaattaag gtcttctatt
    42601 tttatatttc cgcttgataa tatctctgcc atttcatcta ataaattttt ttctgctctt
    42661 gttaattgat tgtatttttt ggaacttaat tctgtccata aatcccatgg aagcaattct
    42721 aaaccaatca tattattaaa gtcatgtaga agattaccct ttacagaatg ccaacctttc
    42781 caatttttat tatatccaaa gtcatctgga tgagcatgtc cttgtcgaca tcttatccag
    42841 gcttctgaac cagttaaaaa accatctgtt tttccgacat catgagtgtc aaaattaatt
    42901 tgaaaataat ttttttgtat gtcatctatt tgtgcatcta ttcttatcca tctctttgtt
    42961 agagtatcat agtattctac aagccagtgg tcttcataag taagctcatt ttcaaaataa
    43021 ttagcaaaac ctgctctcat tctagcctca aaacctcgat atcttaggag cgatacaaga
    43081 agtaaagaat aatctctgca cattccaaca agcctttgtt ttgggtttct tggaatagtt
    43141 agtgggttag aatttatttc aaatattctt tttaacattt gaggaattgt acgaagcaat
    43201 tcctcatcag attgttgctt attaaaggat ataccatata attttccttg gtctccatga
    43261 attactaggc tttgaaccac ttttaataac tcaattggag tctttggtaa atcttgatat
    43321 ttattttcaa attttttagg atttgtgatg atgctttgat ttttatagtt atttattttc
    43381 atttatattt cacctctcta aatggatgat ataccctgac atggtgtcat atgcaaggac
    43441 aatttagatt ttttggccaa aatttaaaaa taaataaaaa atgatacagt gataaattgt
    43501 aatacaaata tagtttcaaa ttgcatataa tataattatt taataaaacc attatctatg
    43561 gaatgttaat gaaatgttaa gatggcattc ttgaatatta agaaatagaa tactataata
    43621 tagtgtgaag gattcttagt aaaaaaattt gtaagtgtta atatacatta aaaaataggt
    43681 ttataatttg gaggaaaaaa atgaaattat caaggtataa gaaaaatagt ttagttctgt
    43741 ctataatttt atgttcactt attatttcaa tccttgtaat tactgttttt aataccgtaa
    43801 aactacacaa tatatctaat aaacaatcta aaaactattt aaacgatgta tctacacaga
    43861 ttgtaatgaa tgttgattct aaaatcaaat ttattttatc cgacttaaga ataatggcag
    43921 attttattaa gcaatatgaa ggtgatagtc gatatgagta tttatctaaa agaaagacta
    43981 gttataagta ttatgatgtt ggaataatag atttagaagg taaagctgag tttttaagtg
    44041 gaaaaaagtt tgacttaaag aatactgctt cctataaaaa aggaattgaa ggtaaagaat
    44101 actcagaagt aatagagtca atgggttttg ttctttatag tgtacctata tttaacgata
    44161 atcatgaagt gtctagtatt ttaataggtg tatccaataa agaaagcatg gatgagattc
    44221 ttaatataga tagctttaat ggagaaggaa ctattgaaat tattaatagt cagggaaaaa
    44281 ctcttttcat aggaaaaaat aatgagttaa taaaagacct tagctataag tataaggatt
    44341 ctgcagatga accttgggca caaaagatgc ttaatgattt taaaaatgat aaatcaggaa
    44401 atattacaat aacctcatca aaaggtgtac aatgcttatt aacttatcat ccaattacaa
    44461 gaggtttaaa tgattggcat tttcttctca tagtacctga agatgttgta cttggtgaac
    44521 ttaataagtt aaattctttt acaataataa tgacatttat aactacatgt attattggaa
    44581 ttataacatt aattttatat attataagaa gaaaatatgt aaatcaaata gaaaatattg
    44641 catatttaga tagtataaca aatggtataa attcaactaa gtttagtatg ctagtcaaac
    44701 ctttaatttc agaatcacct gatagtactt atatgatgat agcaatgaat ataaaagatt
    44761 ttaagctaat aaatgattgt ttcggtagtg aaaaaggaaa tatgacacta aaacatcttt
    44821 acaatatttt gtataaaaac attgatgaaa atgaagaatt tgtgtgccgt catgatgcag
    44881 accttttcta tttgcttatt aagaatagac cagtgttaga agccctggag ttattatata
    44941 aaatagaagc tgacacaaat tattttaata aaaataggga aaatccatac tttttaagac
    45001 tatcagtagg tatttacaca attgaaaatc ataatgaaga tttaattaca atacaagacc
    45061 atgcaaatac agcaagaaaa agctttaata aaactcatca aagtgatttt tctttttata
    45121 gtgatataga aagaaaacga ttaatatctg aaaaagaaat ttcaaattta atggaaaaag
    45181 cccttgaaaa taaagaattt tttatgtgct tacaacctaa aattgatata aaaagtggaa
    45241 aaattagtgg agcagagtct cttgtgcgtt ggaaaaattc agaaaagggc ataatttatc
    45301 caagtaattt tattcctctt ttcgaaaaaa gtggatttat atgtaagtta gatttatata
    45361 tactagaaga aacatgcaaa ttgatttcta agtggataaa agaaggtaaa gaagtgttga
    45421 gaatttctgt taatgtatca cgtcaacatt tgaatgataa attgttttta gaaaaatata
    45481 agcatatatg caataaatac aatgtaccaa catgtctgat agatttagaa cttaccgaat
    45541 ctattttctt agaaaatcca gaagctatag atataataga ggatattcat tctaatggat
    45601 ttaaatgttc tatagacgat tttggatttg ggtactcatc attagggata ttaaaggatt
    45661 ttaaagttga tataattaag ttagaccgtt cattctttgt tagcaaaaat aatatagacc
    45721 gtggtaaggt agttattaag tctattattg aacttagcaa aaggctaggt atgaaagtaa
    45781 ctgctgaagg aattgaagaa ttagaacaag ttgagttcct aaaaaatgta ggatgtgatt
    45841 atattcaagg ttatgttttt tctaaaccat tattaatttc tgattttgaa aattttgcat
    45901 atgaaaataa taaaattaaa aatatccatt attaaatgta caagataaaa aatttaggca
    45961 agttatataa ttaaaaatat aacttgtctt ttttatttat atatttaata aaaatatatt
    46021 tgcagatttt gtaaaaataa ttttcaaatg ttgtaagttg tggctaaagc tttattgtat
    46081 tattctgaat atagaaagat agttactgtc ttagataaaa actgaaacat acataataat
    46141 ataaaatttg ctatattaat aactctaatt attttggaag gagggaaaat atgataagtg
    46201 ggagaatgtt actcatcatg aattttctaa aaggaaaaaa taagacaagt tacaaggata
    46261 ttagcaaaca acttagtata gaagaaagaa aagttagata tgatataaat aatttaaata
    46321 ttgttttgcg ttcattaaac aagtcagtaa tacaaaagat gaacaaaggt gtgttaatta
    46381 ttcctgatga cttccaagta gtatgtataa ataataacga atatgtattt tccttaactg
    46441 agcgagtatc tattatgaaa attatatcaa tgtttaaaat agataatcta aacttagaaa
    46501 aattgagtaa agaatttcag gtttctagaa gttcaattaa aaatgacctt aatgttttgt
    46561 caagtgaatt agaaagaaac caaataacta ttacttatga taaatctttt aaaataagtg
    46621 gagaagaaga ccttatatat aagcaaagat tgaacatatt aaaatcgtat tcttatcttt
    46681 ttggtaagga aaaatctgat ttaagtgtat ttgagaagta tttagtgaat gtaattgaaa
    46741 aaatattcaa agggatttat ttgattgata tatataattg gtctatgaat ttattattgc
    46801 aaatgggatg gactttaaat gatgaatctt ttacatggta tgtgtcaaac attttccttt
    46861 ttacatggta tatacattca gatgaaaaac atcctttaga atctgcttca ttaagtgagc
    46921 catgttttga aaataagttt gaccaagaat ttgaaacaat tattcaaaaa aagttgacta
    46981 aggaacaaat ttttctgtta aagagttttg tattttttac aaataaatat gcaagtttaa
    47041 acgaggatat ggatttgatt agtacagaaa ttatagttca agacctaatt tacaatatgt
    47101 cagaaatatt agagattagc tttaaagaag atatgattct ttataaagga ttactcaatc
    47161 atattgcccc attgatagag agaatcaagc agaatataca gatttatgag gaattacttc
    47221 atgtaatacc agataaatat caatatgtac ttgaagctac taaggtttct attcaaaaaa
    47281 acagagtttt aagtcaaata aagaatgaaa atgaaataat acttttggca atacatttct
    47341 taggaagtat acatagaaat gagaggaata actacaaaaa tatattgtta gtttgtggat
    47401 ttggatatgg tgtaattgct atgttaaagg atagtttagt aaatgattac cagataaata
    47461 tagtagagag tattccatca tataagttac aagattataa agaatgggaa agtattgact
    47521 tcattataac aacatcaaag atagtaatag acttgcctaa aacaattatt gagataaatc
    47581 catttttaca agaagaggat tatttgaagt ttgaagaaaa agggataaaa agaaagaacg
    47641 tcttaactaa ttatatgtca ataaaaaaaa ggttggactt tttagaagaa gatgctcaaa
    47701 aaagagtatt aagtattata tgtcaagaac ttggatacag tgatgagaga atattattta
    47761 gacaacttaa tttaagtgat ttaataggga ttgataccat aaggataatt gatgaagata
    47821 tgaaatggga agatgctgta aaaattagtt caaacatact tgctaattgt gattttgtat
    47881 cagcacaata tgctgagaat attatagata ttttaaaaaa tgtgggtttt tatgctgtaa
    47941 aagataacga atttgcttta ctacatggca atgatagttc attagtcaaa gtaagttcga
    48001 taagtttatt aatatgtaaa gaagcagtta gttttggaga taaaaaggtt aaaatcatat
    48061 tttgtctagc aagcagagat aaaaaagagc aaattcctgc aataattaat ctaactaaaa
    48121 tggtttataa gactaatttt attgctatgt tagaaagtgc aaagacaaaa gaagaagcag
    48181 aagttttaat tcataaatat gagaaggagg tcactgtatg aataaattag ttaatgtaaa
    48241 atgttcattt aaaatacatg ctaattcaaa agaagaagct attgtatcgt tagttgatgt
    48301 agtatcaaaa gaaggatatc taatagataa aaatcaattt ttggaagatg ttttaaagag
    48361 agaagaaaca ttgtcaactt atattggaca tggtataggt cttcctcata gtcaaagtgt
    48421 aggtgttaaa aactcttgta ttacaatagg aaagcttgat attcctattg aatggacaga
    48481 agaaggagaa aaagtggatt taatattttt aatatcagta acaaaagaca atgaaaataa
    48541 tcttcattta aagattttat caaaattagc acgtttattg atgcatgaaa gttttagaaa
    48601 tcaaattaga tgttcagatg aacaaactgt ttataatctt ataaaagaaa aaatagagga
    48661 ggaagattaa aatgagaatt ttaaagtttt tgcaaaaaca tcttatgaca gcaacatctt
    48721 atatgattcc atttgtggtt gcaggaggaa tattatttgc tttatcagta actctaagtg
    48781 gacaagctgc tgttcctgaa acaggctggt tggctaaact gaatcaaatt ggagctgctg
    48841 gcttggcttt attcattcct atattaggtg gatatatagc atttagtatg gcagataaac
    48901 caggattagc tccaggtatg ataggtgcat atttagcaaa agaagtaaat gcaggtttta
    48961 taggtggtat catagcagga tttatagcag gatttgttgt tttacaatta aagaaaatta
    49021 aattagctcc tacaatgaga actttaggtt ctatatttat ttatcctttg attggtacat
    49081 tgattacagg tggtataatt gtatttttaa ttggagaacc tatagcttct tttatgacat
    49141 ggatgacaaa ctggttaaat ggaatgtctg gtgtttctaa aattccttta ggtggaatct
    49201 taggaggaat gatagcctca gatatgggtg gtcctataaa taaggttgct gctacttttg
    49261 cccaaactca agttgacaca cttccatatt taatgggtgg agttggcgtt gcaatttgta
    49321 tacctccaat tggtttagga ttagctacat tattgtttcc aaaaaaattt agcaaggaag
    49381 aaagagattc aggtaaagct tcgctattaa tgggatgtgt tggaattaca gaaggagcta
    49441 ttccatttgc aacatcagat ccagttagag taataccttg tattatggct gggtcgatta
    49501 taggaaatat tatggctttt ttattaggat gtttaaatca tgcaccctgg ggaggtctga
    49561 tagtattacc tgtagttgac aataggttgg ggtatattgc atcagtatta actggagcag
    49621 tagttgttgc agtattaatg aaattagtaa aaaaagacgt gaaagaagat gaagaaattg
    49681 aagaggattt agatgaatca attgaattaa tatttgaaga attataaata taaatggaag
    49741 gaatttgtat aaaaaagtaa atataaaact ataaacttaa aggagataag aatatgaaaa
    49801 ttgtagcagt aacatcttgt cctagtggag tagcacatac ttacatgtcg gctgaatcac
    49861 ttgaattatc ggccaaaaaa tttggtatag aaataaaggt tgaaactcaa ggaagctctg
    49921 gaatagataa tgaattgtca cttaaagata ttgatgaagc aacttgtgta atattgacta
    49981 atgatgttga gattagaaat atggaacgtt ttaagggaaa gaaggtagta agaatgagtg
    50041 tatctgagat aattaagaaa tctgatgcat taattaagaa aataaaagat acttttcaat
    50101 aaaaattgat ttattttaca tataactcaa agatgttttt aaagaaattt ttattaaaag
    50161 catctttgaa aatatcttaa aaatagaata aaaggagata tagtcatgaa aaaattacca
    50221 ataaagactg tcgtacaaag attactagac ttacaagaag aggggaaaag tgcaactctt
    50281 ttaggaattg gtcctatgtc accaaacttg ttacaagcaa gttttgaact agcaaaagat
    50341 gatgattttc ctttaatgtt tatcgcaagt agaaatcaag tagatgcaga tgaactaggt
    50401 ggcggttatg taaatggttg gaatcaggaa acttttacaa aagatattaa gaagattgcc
    50461 gacaaagttg gatttgatgg tttatattat ttatgtagag accatggtgg gccatggcaa
    50521 agagataaag agagaaatga ccatttgtct gttgatgaag caatggagtt aggaaaaaaa
    50581 tcttatttag cggacattga agcaggtttt gacctattga tgattgaccc tacaaaagac
    50641 ccatttgaaa ttggaaaagt aattccacta gatgtagtac tagaaagaac tgtagaatta
    50701 attgagtatt gtgaaaacga gagaaaaaga cttaatctac cagacatagg ttatgaggtt
    50761 ggtacagagg aaaccaatgg aggtcttact tcaactgaga cgtatgaaac atttataact
    50821 agactaaagg ttgaacttga taataggggt ttgccaatgc caacatttat agttggtcaa
    50881 actggtactt taactagaaa gacagaacaa gtaggaactt ttaattttag aaatgcttat
    50941 gatttagctc aaatggctaa gaaatatgga gttggtttaa aagagcataa tggcgattac
    51001 ttagatgatg taactttatt agaacatata ccatctcaaa ttattgctac aaatgtagct
    51061 cctcaatatg gtactgaaga aactagggca tatttaaaat tagcagaagt tgagtgtaaa
    51121 ttagaaaaag agggcctagt tgataaaact tctaatatca gacatgttct tcttgttaat
    51181 gcaattgaat gtggacgttg gagaaaatgg gtagtaggag aacaaaaaaa tctaactact
    51241 gaagagatat ttaagaatga agttttatct aatgaaatac tagatattgc aggacattat
    51301 acatttaata atgatgatgt taaaaaagaa atagaagtgc tttatgataa tttaagtaag
    51361 aataatattg atggtcaaag atttgttgta gaccatatta aacgtccttt gcgtgattat
    51421 gcagaatgct ataacttaaa aggtgttact acgaggattt taaataaata ataggactta
    51481 tagtggtgag tattgttata ctaggtattt atagttataa ttatacttac cactattaaa
    51541 tttaggagga ctaatatttt gattaattta atttttgatg tagatgatac tttatataac
    51601 caattaacgc ctttttacac tgcatataat aaagtgtttt cttcaataaa ggatatttct
    51661 attgaagatt tatatatgag tagtagaaag tatagtgatg aggtatttca tatgactgaa
    51721 aatggagaaa tgccaatcaa agaaatgcat atttatagga taatgaaagc ttttgaggag
    51781 ttgggaaatt ctattacaga aaaagatgca caaagttttc aagatgagta tatatatcag
    51841 caatcacaaa ttacactaat accagaagtt gagaggattt taaatttttc taaagaaaga
    51901 aatattaatc taggaattat aactaatggc ccatcaaacc atcaaagaat gaagttaaag
    51961 cagttaaata ttgaaaattg ggttgataaa agtaatattt ttatttctag tgaggttgga
    52021 ttttctaagc cagatactaa tatttttaga gtagctgaga atgttatgaa tttagataga
    52081 gaaaatacat attatgtggg tgattcttat agaaatgatg tattaggtgc taaaaaagct
    52141 ggttggaaga gtatatggtt gaaccataga ggacatgagg tagaagagtt gttttataaa
    52201 cctgattttg taattttgga acataaggat ttgatatctt tatttataaa aatatgtagt
    52261 tataaaaata tgtagtaaaa aaatgttaat aatagaattg tataaaataa ttaataataa
    52321 ctatataaaa ttatatgttt agattgtgag caatctattt tatgttaaaa atagattatt
    52381 tagaagaagg ggaaatctta aaaaaatttg aatatcccct ttttattatt taattaaaat
    52441 gaaatagtta gaaatatatt ttatttagtt tagtcaataa cattttggga ttctttataa
    52501 ctacatgtta actgttgaat aggcttatca tatggtttaa cccatccttt attaatactt
    52561 aattctgtaa gtgctgtgtg accttctacc atttgagtta gtgaagctga atatatagct
    52621 cttaattcag gtgtactact tgttaatgca gaattaagat acatattggc agatgcttta
    52681 gcagatgaaa gcatacttaa cattattact ttatcgtcta tataagtatt gttcttaatt
    52741 agattttcta tcatatttct catgttatct atacctcctc agaaattagt atttcatttt
    52801 caactataaa ttgttgtata gctttaattc ttccttctgt tgctaatata ctagattctg
    52861 attgtctttt taggtcttca tctgatatta acatatttat tgctctttgc ataagtaatc
    52921 cgtcagactc catttttata actgctgcta aagatatttt ttcagtttct gaaagtgttc
    52981 tcatttaatc atctcctata ttgtaattta tgctttaata gtatgtcttt cttttcaagg
    53041 aaataaccat tacacttttt tacagtattt tatattctct ttatatcaaa gtttagtcaa
    53101 cttaatatat taatataatt ttgtaggata tttatcatta aatatctata aaataaatta
    53161 tttgaatatt cataaatcaa aatttatttg tatgtacttc ttcaagagtc aatatgaatt
    53221 ttttcaaaaa attaattttg atgataatca ttaagggcta tatttttcct aaagttgtga
    53281 ttatcattat taatttacta aaatacttta atgaaaaata gctaacttta attgtaggat
    53341 attcttaata tatttgaaat aaataaaaat attgaaggat ataatattca attggtatat
    53401 aaataataaa tgatagttaa gatttacctt agaggctaat taggtgttca gtcaaaatta
    53461 atgcctttag aatacaaatg tattctaaag gcatttttac tatgtatttt catttatatt
    53521 actaaacatt atctattttt atatacattt ctatgtattt tattttcatc aaatcggtct
    53581 ataaattcat ttttttcttc actatatcca atagatataa gtgcataagg aactaatttt
    53641 actggtaagt ctaaaatttg tttaacttta tttactactt tatttttagg aaatactcct
    53701 gcccaacaag cagctagacc ttgattagta acttctaata ataaattttg tgtgcaagca
    53761 cctaaatctt gtatccattt accaggtttt aagaatttat ctctatttcc aagcactact
    53821 atacataatg gtgcaaattc tatatgcttt gctctatgct gtgactttga gagctctttc
    53881 agcagttcct tatcatctac tataataaat tcccaaggtt gagcattttt tgatgaaggt
    53941 gcttgcatag ctgattttag tatttcagtt attttatctt cttctatatt tttatctata
    54001 tatgttctta ttgaacgtct attttttata acttctaaca tacagattct cctttaaata
    54061 aaattatttc tatttatata atatcattac tttaagtttt agctattact tatataaaga
    54121 ataaactttg tgttggtttt atctaagtaa aagtaacatt cagaactaaa aaacaagact
    54181 ataaatccaa gatattaatt aaaaaagaag taataaaaaa taatatacaa gatttaaaaa
    54241 agagtattga gcttaaaatt taattagaaa accaattttg agataatctg ttttttattt
    54301 taacaaaaaa acataaataa agttcgatac gtagcgaatg aaaaaaatac aagaaatatt
    54361 ttttttaaaa aatttcaaaa aagagttgat aatatatgta tattaatata aaatttaagg
    54421 tgtataattc gtataataat acgaatgatt tgtagtgtaa aataacttat aaacggagag
    54481 gggaagtcta atgaaagtag cagtagttat gggttcaaaa tcagattatc caaaattaga
    54541 agaagggata aaactgcttg aaaaatatgg aatagaggtt gtagcaagag cattatcagc
    54601 tcatagaaca ccagaacaac tttcaatatt cctaaaagaa atagaagatg atactgatgt
    54661 aataatagca gcagcaggaa aagcagcaca cttaccaggt gtaatagctt cacaaacatt
    54721 aattcctgta ataggattac ctattaaatc atcaactatg gatggactag actcactttt
    54781 atcaatagtt caaatgccaa aaggaatccc agttgcaaca gttacaatag acttaggttt
    54841 aaacgcagct ttattggcat tacaaataat gactttaaaa tacccaaaat taaaagagga
    54901 tttgaaatca tatagagaag agatggcaca aaaggtgtta gaagacgaca agaatttaag
    54961 ggggtagcag aaatgttatt atatgaagga aaagcaaaac aagtatattc tacagataat
    55021 gaaaatgaat atgttgttta ttataaagat gatgcaacag catttaatgg agaaaaaaaa
    55081 gcagaaatat cttcaaaagg tatactaaat aataagatat caacaataat ctttgaaatg
    55141 ttaaaagaaa ataatataaa tactcacttt ataaaaagtt tatcagatag agaaatgtta
    55201 gttaaaaaag tagagatttt accattagaa gtaatagtaa gaaatattgc tgctggttct
    55261 atctgtaaaa gagttggtct tgaagaaggt gtagttttcg atgagccaat ttttgaaata
    55321 agttacaaaa atgatgctta tggtgaccca atgctaaatg atgattatgc agtggcaatg
    55381 aagttagcaa ctagagaaga gttaaaattc ttaagagaag aaactttaaa aataaacgag
    55441 ttactaaaag catttttctt aaaattaaac ctaaagttag ttgactttaa aatagaattt
    55501 ggtaaggatt ctgaaggaaa tataatattg gcagatgaag tatcaccaga cacttgtaga
    55561 ctttgggatg taaatacaaa tgaaaagtta gataaggaca gatttagaaa agaccttgga
    55621 gaccttgtag aaggttatac ggaagtactt tcaagaatga ataataaata ggaggcaaat
    55681 gtatgtgtgg agttttaggg atttactcta ataaagatgt aactaaagaa ctatattatt
    55741 ctttatattc tatgcaacac agggggcaag aaagctgtgg tttagctctt ttagatgatg
    55801 gagaaattaa gtacaaaaaa gatatgggat tagttggaga tgtttttaag gaaaatgaat
    55861 tatctaagtt aaaaggaaat atagggattg gacatgttag atattcaaca gctggaggaa
    55921 gtcatgtttc taactgtcaa cctttagttg gaagttgtag aaaaagacaa ttagccatag
    55981 ctcataatgg aaatctagtt aatgcaaatt atttaaaaga tatgctagaa gaagatggat
    56041 atatgttcca aactaattca gatacagaag tgattttata tatacttgct agatattaca
    56101 aaggggatat agtagaaagt ttaaaagtga caatggatta tataaaaggt gcatatgctc
    56161 ttgtaataat gagtcaagaa gaattggttg cagttagaga cccacatgga ttcagacctc
    56221 ttgtacttgg taaaaagggt gatgaatata tatttgcatc agaaaattgt gcaatagata
    56281 tacttggcgg agaagttata agagatgtag agccaggaga gataatagta gtcaaagatg
    56341 gagaactaaa atcatatttt tattcagaaa attataaacc agttaagaaa agttgtatat
    56401 ttgaacacat atactttgca agaaatgatg caactataga caatgtaaat gcatatgaat
    56461 ttagaattaa atgtggtgag agattagctc agaatgaaac tgtaaaggca gatatggtag
    56521 ttccagttcc agattcaggt tggccaggag ctattggtta tgcaaatgct agtggattaa
    56581 aaataagtga aggcttagtt aaaaatagat atgtaggaag aacatttata aaacctacac
    56641 aagaagaaag agaaatagca gtaaaaataa aattaaatcc tctttcaaca ataataaaag
    56701 gaaaatctat aattttagta gacgactcaa ttgtaagagg aactacatct aaacaattag
    56761 taaaatcttt aagagaagca ggagcaaaag aaattcatct tagaataact tctcctccag
    56821 tagcttactc ttgttactat ggaatagata ctccaaatcg ctctaaatta attgcatcaa
    56881 gtaacaacgt agaagaaatg agagaatata ttggatgtga tagtttaaaa ttcctagata
    56941 tagaaggaat gttagatgca acagaacata agtctacttt ctgtaaagct tgttttgatg
    57001 gagaataccc agttaagaaa attgataagg aggaactact ttcatgttaa catataaaga
    57061 atcaggtgta gatatagatg aaggaaatag agcagtagac cttataaaag gtaaaataaa
    57121 aggaacttat gatggaaatg tagttggaga tttaggtaac ttcagtggat tatacagttt
    57181 aaaagatttt gtaggtatga aagaaccagt tttgcttgca tctacagatg gtgttgggac
    57241 taagttaaaa atagctcaga tgatggacaa gcatgatact gttggaatag atttagttgc
    57301 aatgtgcgtg aatgatttaa tttgtcaagg agcaaaacca ttatttttcc ttgactatat
    57361 agctcttggg aaattagtgc ctgagcatat cgaaaaaata gttggtggaa ttgcagatgg
    57421 ttgtaaaatg tctggttgtg cactaattgg tggagaaact gctgaaatgc ctggaatgta
    57481 tggagaagat gactatgatt tagcaggatt ttctgtagga atagcagaca aagaaaagat
    57541 tgtttctgga aacaatgtta aatcaggaga tgtattggtt ggtatatctt caagtggagt
    57601 acacagcaat ggattttctt ttataagaaa gatattttta gaaacttaca attataaaat
    57661 ggaacaatat gttgaagaac taggaatgac agttggagaa gcacttttaa caccaactaa
    57721 aatatatgtt aaattagctt tagatgtatt agctaaacat gacataaaag ctatagctca
    57781 cataactggt ggagggctta tagaaaatat aacaagagtt atacctaaag ggttaggact
    57841 agatatcaat aaaaaatctt gggagaagcc tcctatattt aaaatgatag aaggttttaa
    57901 tgctgttgat gagagagaac ttcataagag ttttaacatg ggtattgggc tagttttaat
    57961 agtagataaa gaaaatgctg atgatgttgt aaactttata aataatagag aaaatgacaa
    58021 tgctgcttat gtagataaaa aatacagtga attattagaa gataaagcgt atataattgg
    58081 tgaagtagta gatagtcatg aaggtgtaga attatgctaa atataggagt tttaatatct
    58141 ggtggaggaa caaatttaca agcagttata gatggcactg agtctggaga aataaaaggt
    58201 caggttaaag tagttatctc aagtaagcaa ggtgcttatg ggctagagag agctaaaaat
    58261 cataacataa aagcaatttg tgaaactgat gaagacaaga taatagagat tcttaaggaa
    58321 aataaaatag atttagtagt tttggctggt tatttaaaaa taatcagccc aaagctggtt
    58381 aatgagttta gaaacaaaat gataaacata catccatcat taattccttc attttgtgga
    58441 gctgggttct atggagaaaa agttcatcaa ggtgttatag attacggagc taaagtaact
    58501 ggtgctacag ttcattttgt tgatgaaggt gctgatactg gaccaatcat aatgcaagat
    58561 gtagttaagg taaatcaaga tgatgatgca aagacacttg caaaaagagt gttagaagtt
    58621 gaacatagga ttttaaaaga aagtataagt cttttttgtg aaaataaatt aaaacttcaa
    58681 ggtaggagag tgtttataaa tgagtaagag agctttaata agtgtaactg acaagactgg
    58741 tgtagtggaa tttgctaagg agttaaataa gttagattat gaaattatat ctacaggaaa
    58801 tacatttaaa acattaaaag aaaatggtgt taatgtaatg caagttgaag atgttacaaa
    58861 ttttccagaa atattagatg ggagagtaaa aacattaaat ccatatatac atggtggtat
    58921 actttataaa agagataaag aatctcatgt agaaactgtg aatgagcata aaatacattc
    58981 aatagattta gtagctgtaa atctatatga ttttgaagga actttaaaag ctggaaaaag
    59041 tcatgatgaa ataattgaaa atatagatat tggtggacca tctatgatac gttctgctgc
    59101 caaaaactat aaagatgtaa tagtagtagt agatataaaa gattatgatt ctataataga
    59161 aaaattaaaa acagatacaa tgacattaga agacagaaaa aaattatcat ataaagcttt
    59221 ctcaactaca ggaagatatg atgcgttaat atctagttat tttgctggag aagttggaga
    59281 tacatatcct gacatattaa atttaacttt ccaaaaagaa caaactttaa gatatggaga
    59341 aaatccacat caaaatggtt tcttatattc acaatcaaat gcaaaaaatc caatcttaaa
    59401 ttatgagcaa ttaggcggta aagaactttc ttttaacaat ttaaatgatt tacatggatg
    59461 tttagaagta atgagagaat ttaaagatag tgaagaagta gtttcagtag ctataaaaca
    59521 tgctaattca tgtggggtag gtctaggaaa agatgctttt gaagcatata caaaatgtta
    59581 tgaagcggat aaggtttcaa tatttggagg aatagtagga ataacttcta ctatagataa
    59641 agctacagca gagaaattaa atgaaatatt cttagagata gtagtagcat atgattttga
    59701 gccagaagct ttagaggtac ttaaacaaaa gaaaaattta agaatattaa aattagctaa
    59761 gatagaagat agtttacaac catatgaaat gaaatattta gatggaaaat tattaataca
    59821 agatagaaat aatatattag cagaaaaaag tgaaaatgta acaaaagcaa aaccaacaga
    59881 tgcacaactt aaggacatgg aatttggtat gagagtagta aaaaatatga aatcaaatgc
    59941 aattgcgata gtaaaaaatg gtcaaacttt agctttaggt tgtggacaaa catcaagaat
    60001 ttgggcatta aaaaatgctc ttgaaaataa caaagataaa gattttacag gagctgtttt
    60061 agcgtcagat gcatttttcc catttgatga ttgtgtaaca ttagctcatg aatatggaat
    60121 atcagcagta gttcaaccag gtggctctat aaaggataaa gattcaatag aagcttgtga
    60181 taagtatgat atggttatgg tatttacagg aataagacac ttcaaacact aaggaggata
    60241 ttatgaagat attggttgta ggcggtggcg gaagagagca tgctatatgc tggaaactaa
    60301 gcaaagaaaa aaatgtagaa aaagtttatt gcgcgccagg taatgcagga attacaaatg
    60361 tagcagaatg tgtaaatata ggtgatacta atatagaaga acttttaaaa tttgccaaag
    60421 aaaatgaaat aggtctgaca atagtaggac cagaagtacc actagttatg ggaatagtag
    60481 atgagtttga aaaagaagga ttaagagtat ttggacctaa taaaaaatgt gctcaacttg
    60541 aaggaagtaa agctttttca aaagaattta tgataaaaca taacatacct actgcaaaat
    60601 ataaagaata tacaaactta gaagaagcta tatcagaaat agatagtttt ggatatccag
    60661 tagtaataaa agcggacgga ttagctgctg gaaaaggtgt tgtaatacct gaaaatagag
    60721 aagatgctat agcaacttta aaagaaatga tgtcagataa gaagtttgga gctgctggag
    60781 ataaaatagt aattgaagag tttttaaaag gaatagaaac ttcaattcta gcatttgtag
    60841 acaatgatac aatagttcct atggcaagtg caaaagacca taaaaaagta aacaactatg
    60901 agcaaggtcc aaacactggg ggaatgggaa ctttttcacc tagtgaaata tatacagaag
    60961 aattagcaaa taaagtaaaa gagacagtat tagaaaaaac tttagaaggc ttcaaaaaag
    61021 atggacttaa ttttaaaggt attttatttg ttggtcttat gataactgaa gatggagaaa
    61081 aagtacttga atataatgta agatttggag accctgagac acaatctgtt ttatttagat
    61141 tagaaacaga tttacatgag ataatggaaa ctatactaga taataagtta aaagatatag
    61201 aaataaacta tagtgatgat gaagctgtat gtgttatgct tacatcagga gggtatccag
    61261 acagttatga aaaagggaaa attataactg gtcttgaaaa cttggatgat gatatagtag
    61321 tattccatag tggcactaag atgcttgatg gtaatttagt taccaatgga ggaagagtaa
    61381 ttggtataac tgcaaagtca actacagtta aggatgcagc agaaaaagtt tatgaaaaca
    61441 taaagaagat aaactttgaa ggaatgcact atagaacaga cataggaaga taatttttct
    61501 aaaatggagg ataaggtatg ttgaatactg aaaataaaga ctcaatggtt agaagagtat
    61561 tagttgaaaa aagagaaggt tttgaccttg aggctaaagc tttaaaaaaa gacttagtag
    61621 aaagtttaca catagataat atagaaaatt taagaatatt aaatagatat gatgtagaag
    61681 gaatatcaga agaagtttat gaaaatgcag caaagacaat attctctgaa ccaaatttag
    61741 atgtagtata ttatgaagaa ataccaaaat taaatgatga aagagtattt gcaatagaat
    61801 ttcttcctgg tcaatacgac caaagaggtg attgggcagc tcaatgtgta caaattgtaa
    61861 atcaagggat aagacctgct attaatacag caaaagttta tatattatca ggcaaaataa
    61921 ctgatgaaga gttttctaaa ataaaagatt actgtataaa tccagtagat agtagagaag
    61981 catctttaga aaaaccagaa acattaaaaa tggaaactga aataccaaca acagttgaag
    62041 tattagatgg atttatagat ttagatgaaa atggattaag aacatttgta agtgaaaaag
    62101 gattagcaat gactttagga gacttacaac acgttcaaaa atactttaaa gatacagaaa
    62161 agagaaatcc aactataaca gaaataaaag tattagatac ttattggtct gatcattgta
    62221 gacatactac ttttatgact gaaatagaaa atgtaaagat agaagatggt aagtttaatg
    62281 atatagtaaa agaagcgtat caaatgtatc ttaactcaag agacaatgta tatgtgaaca
    62341 gacataaaga tatatgttta atggatatag ccactgttgc agtaaaagaa ttaaagaaga
    62401 atgggaaatt aaatgaccta gatgaaagtg aagaaataaa tgcatgtagt ataaacgtag
    62461 atgttgaagt tgatggtaag atggaaaaat atctagtaat gtttaaaaat gaaactcaca
    62521 accatccaac tgaaatagaa ccatttggtg gagcagctac ttgtttaggt ggagctataa
    62581 gagacccatt atcaggaaga agttatgttt atcaagcaat gcgtgttaca ggaagtgctg
    62641 acccaagaac gactttagaa gatactttac ctggaaaact tatgcaaaga aaaataacta
    62701 cagaagctgc tcatggatat agttcatatg gtaaccaaat aggtcttaca actggacaag
    62761 ttgcagaagt atatgatgaa aactttgttg caaagagaat ggaaataggt gcagttatag
    62821 cagcagtacc aaaagagaat gtagtaagag aaagacctga agcaggagat gtaatagttc
    62881 ttcttggagg aaaaacagga agagatggtt gtggaggggc aactggttca tctaaagaac
    62941 atagtgaaga gtcaatctta acttgtagtg cagaagttca aaaaggagat gctcctaacg
    63001 aaagaaaaat acaaagattc tttagaaata aagaagttgc tcaaatgata aaaagatgta
    63061 atgattttgg agcaggtgga gtttgtgttg ctataggaga gattgctgat agtttagata
    63121 taaacttaga cttagtacct aaaaaatacg atggacttga tggaactgag cttgcaattt
    63181 cagagtcaca agagcgtatg gcagtagcta taaaaaaaga aaataaagat aaatttatac
    63241 aattagcagt agaagaaaac ttagaagcta cacatgtagc tacagtaaca gatacaggat
    63301 atttaagaat gttctggaat ggaaaagcaa ttgtagatat aaatagagag ttcttagata
    63361 caaacggagt aaaacaaact actgatgtcc atgttactaa agtagatgaa gaaaatacat
    63421 tctttagctc taatgaaata gtaaaagatg ttaagtgtgc aagtatgaaa gacaagttta
    63481 caaaagtatt atctgacctt aatgtttgtt ctcaaaaagg attagtagag atgtttgata
    63541 atacaattgg tggtaataca gtacttatgc catttggagg aaagtatcaa gcgactccaa
    63601 cacaaggtat ggttgctaag ataccagtac ttggaggaga aactaatact tctacaataa
    63661 tgacttatgg atataatcca aaggtaggaa aatggagtcc attccatggt gccttgtacg
    63721 cagtagtaga atctgtgtgt aaattggttg ctattggagg aaattatagt acaacaagac
    63781 ttacattcca agagtatttt gaaaaacttg gtaacaatcc agaaaaatgg ggtaaaccat
    63841 tctcagcact tttaggagca ttttatgcac aaagtaaatt tgagatacct gctataggtg
    63901 gaaaagacag tatgtctggt acatttaaag atatcgaagt tccaccaaca ttagtttcat
    63961 ttgctgttga tacagtagat gcgaagaaag tagtatctcc agaatttaaa aaagcagact
    64021 caaaagtagt aatgttatgt gtaaacaagg cagaaaatga tgttgtagat tttgaggaat
    64081 taaagagaaa cttagacaaa gtaagagaac ttatacatgg aaataaagtt ttatcaacat
    64141 atgcattagg atttgcaggt gtaggtgaag caataagtaa aatggctttt ggtaataaaa
    64201 taggatttaa gtttagtgaa gaagctgaaa aaacatttac agatgataaa ttatttgagg
    64261 ctagttatgg aaatatagta cttgaattag caaatgatga tttatgtatg ttagaaggat
    64321 acaattatgt tgtgcttgga agtacaacta aagaagctag tatatttatc aaaggtgaag
    64381 aacttgcatt agatgaatta tataaagcac actgtagtac tttagagcct atattcccaa
    64441 ctaaaacaga agaagtaaaa tcaaagatag agactataag ttatatatca caaggagaag
    64501 ctaaaaaatc atcattaagt atagctactc caagagtatt tataccagca tttcctggaa
    64561 caaactgtga atatgactct gcaagagcat ttgaaagagt aggagctaat gcaaacataa
    64621 gagtattcaa gaatttaact tataaagaca tagaagattc tatagataca atagtaaacg
    64681 aaataaaatc ttctcaaata ataatgttac caggtggatt tagtgctggt gatgagccag
    64741 atggttctgg taaatttata gctactgtat ttagaaatcc tagagtgcaa gaagctataa
    64801 atgaattttt aactcaaaaa gatggactaa tgttaggtat ctgtaatgga ttccaagtat
    64861 taattaaatt aggattagtt ccatatggag aaataagagt tccaagtgaa agtgctccaa
    64921 cacttactta caataatatt ggtcgtcatc aagctaagat tgctagaact agaatttcat
    64981 ctaataaatc tccttggtta gctcaaacta atgttggaga tattcataat atagcaattt
    65041 ctcatggaga aggtaaattt gttgctagtg aagatgttat gagagaatta attgctaatg
    65101 gacaagtagc aactcaatat gttgacttta ataatgaagc tacttatgat attgagttta
    65161 atccaaatgg ttcattctat gctgttgaag gtataactag tgctgatggt agagtgtttg
    65221 gtaaaatggg acattctgag agaattggtg aggaagtatt taagaatatt ataggtgaaa
    65281 aagaccaaaa gatatttgaa tctggagtta aatattttag ataaagcttt gatgtttaat
    65341 tgatagctag aatatataat ttagatattt agatttaaag agatgtaata atatgatgat
    65401 aatcatttaa tattacatct cttttttatt tatctaagaa ataataagtt caacctaagt
    65461 taaaatacaa gctgtgttat aattaattac taagtaaaat taaatattta ttggagggca
    65521 acataattaa tgaaaatatt aataacaggg tctaatggtc aattaggaaa agaattggtt
    65581 agccaattag aagcaatcaa tcaaagtata aatcaaccaa aatacgttat attagctaca
    65641 acaagaaatg atttggatat atccaatcag actaatatag ataattttat tttgcataat
    65701 aaacctgatg taattgtaaa ctgtgcagca tatacaaagg ttgatgcatg tgaagataat
    65761 atcgaaattg cgtataaaat aaatgcctta ggagtgagaa atttagcaat agcatcagaa
    65821 aaagttaatg ctaagcttgt tcacatatca actgactatg tattcaatgg tttttctaaa
    65881 tatccatata gggaagacaa taaaactgaa cccaattctg tgtatggaaa aagtaaactt
    65941 atgggagaaa agtttgttga acaattctca cataagtact ttatattgag aacagcatgg
    66001 ttatatggta atgggaataa ttttgtaaag actatgataa aactttcttt agaaaataaa
    66061 gaggttaatg tggttaatga ccagtttgga accccaacaa gtacagtaga cttagcaaaa
    66121 attataataa gaatcatgga aacagaacat tatggagttt atcatgctac atgtgaaggt
    66181 gagtgtagtt ggtatgattt tgccaaaaag atatttgaat taaaaaatat agatataaaa
    66241 gtaaatccaa ttaagagtaa cgaatttaaa tgtaaggctc aaagaccact atattctgta
    66301 ttggataatt ttatgttgaa gttaattggt ttaaattctt ttagaaagtg ggaagaatcc
    66361 attgaagaat atttagaaag atatgatata aatgaaaagt aaatgtatta tttttagaaa
    66421 agaaaataag atattataaa aaatataaat atttctttta tttatccgat aatcataata
    66481 tgacaaaaac aaatttaagg atggaaaaag atgaaaggaa ttattttagc aggagggtct
    66541 ggtacaagac tatatcctat aacaaaatgt atatcaaaac aaacacttcc aatatacgat
    66601 aaaccaatga tatattaccc tatgtcggtt cttatgttgg cagggataca agatatatta
    66661 ataatatcta caccaagaga tataaaagca tttgaagaat tatttggaga tggaagttca
    66721 ctagggctta aaataacata tgcaattcag gagaaagcaa atggaattgc agaagcgttt
    66781 ataataggag aagaatttat aggaaatgac agagtgtctc ttgtattggg ggataatata
    66841 ttttatggat atggatttag tgaaaggttg gagaatgcag ttaaaagaaa aggagcaact
    66901 atatttgggt atcatgtaag taatccaaat tcgtttggag ttgtagaatt tgataaggat
    66961 tttaatgtat tatcaataga agaaaaacct acagttccta aatctaatta tgctatacca
    67021 ggattatatt tttatgataa tgatgttgta gagatagcaa agctagttga accatcagat
    67081 agaggtgaat tagaaataac ctctataaac agtgaatatc taaaacgagg aaaactaaaa
    67141 gtggaacttc taggaagagg tatggcttgg cttgatactg gtacacataa aggtctattg
    67201 gatgcttcta actatgttga agtggttcaa acaagacagg gactgtatat agcatgttta
    67261 gaagagattg catatacaaa aggatatata agtagagaac aattaatgaa actagccaag
    67321 ccactgataa aaactgaata tggtcaatat ctattaaaat tggctagtga agatatgcaa
    67381 tatggtagat aaaatttatt ataaatttta ttaagggagt ttgttataat gggaaaaatc
    67441 aatgttataa agactaaaat agaaggatta tatatagtcg aaccaaatgt attttgtgat
    67501 gaaagaggat attttatgga aagctataat aaaaaggatt ttatagagca gggtcttgat
    67561 atgtgtttta ttcaagataa tgagtctagc tcaagaaaag gtgttttaag aggaatgcat
    67621 tttcaggtta gatatcctca aggaaaatta gtcagagtta cagagggaga agttttcgat
    67681 gttgcagttg atttaagaaa agattcacag acatttggga aatgggaagg tgtaatattg
    67741 tctgataaga ataaaaaaca attttatatt ccagaagggt ttgcacatgg atttttagtt
    67801 ttatcagaaa aagcagtatt taattacaaa tgtacaaact attattatcc agaatttgag
    67861 catgggttta tatggaatga caagcaaata tctattgagt ggcctttaaa aggaattgaa
    67921 gaaatatttt tatcagaaaa ggacaaaaaa caaaaaagtt ttaaagatat ttgtataaga
    67981 cgttaataaa aatttattag aattaacatt taggagaaaa aatatgaaaa aaatactgat
    68041 aactggagga gcaggattta ttgggagtaa ctttgtacat tatatgctta acaagtatgt
    68101 agattatttt attgttaacc tagacttgtt gacttatgct ggtaatttag agacattaat
    68161 agaaatacaa gacagttcca attataaatt tgttaaagga gatatttcaa atagggaaca
    68221 gatgtataag ctatttgaag aagaaaggtt tgatatagtt gttaactttg ccgctgaatc
    68281 tcatgtagat aggtcagttg agaatcctga tttatttatt aaaacaaaca ttataggaac
    68341 acaagtactt ttagatgcat ctataaaata tggagttaaa aggtatcatc aaatatctac
    68401 agacgaagtg tatggtgatt taccaattga tagaaaggat ttattcttta cagaacaatc
    68461 tcctatcaat ccaagttctc catattcagc ttctaaagca tcagcagatt tgttggtaag
    68521 ttcttattat agaacatatg gattgttaac aactatatct aggtgttcca acaattatgg
    68581 gccatatcat tttcctgaaa aattgatacc tcttatgatt ttaaatgctt tggaaaacaa
    68641 acaattgcca gtatatggga atggggaaaa tgtaagagat tggttacatg tatatgacca
    68701 ttgtactgct atagacttaa taatacataa agggaatata ggggagattt acaatatagg
    68761 aggtcataat gaaagaagta atttagaagt agtaaaaatg atattaaatc ttttagataa
    68821 atctgaagag ttaatatcct atgtaaatga tagacctggt catgatttaa gatatgctat
    68881 tgatgcaact aaaatagaga atgagttagg ttggaaggca aaatatgact ttgatttggg
    68941 tataaaagaa actgttaagt ggtatataga aaatgaatct tggtggaaag ctgttttatc
    69001 agtgtaactt tgaaatttat aaaatttaga aaggggcgtt ttatattgaa tgagataagt
    69061 tcactaatta atatattagc attgactcaa ttatctggta gtaatactac aaatcaatgt
    69121 aactgtacat ataatagttc atctggattt gatatgatta tgatgacctt gttaaaagca
    69181 ttatcacaaa ataatcaaca gacttctaat ggctacaatt tatcgtctaa ttctgagaat
    69241 ttatttgacg aactcggcag tgtagtaaat aatacagcta gtagatttat agatgttgat
    69301 acaaaagata aaagtgtaaa atcaagaatt gaaaatgcta tagagcaagc atcaaaaaaa
    69361 tataatgtgg attcgaatct tataaaagca ataattaaag ttgaatcgga ttttaatcca
    69421 aatactgttt cttctgctgg tgctaagggt cttatgcaac ttatgccaga aaattgcaga
    69481 gacttggggg ttacagaccc ttttaatata gagcagaata tagatgctgg aactagacat
    69541 attaaggaat acattgatat gtttggaggg agcatagaaa tgggattgat ggcatataat
    69601 ggtggtcctg gaagaatgaa aagtagagga gtagaatcaa tctctgacct gtataaaatg
    69661 ccaaaagaaa cacaaaatta tattcctaag gttatgaaat attatagagg gtaggcttta
    69721 ttatggggat aaatatagat aagctaaaca taagtccaag tataaatatg gaggttaaaa
    69781 aactaaaaga gagtaataaa ttttctgaca aattaaactc tttaaaacaa tcttcttcat
    69841 tggaagatat aaaacgaaat ttggaaagtg taaaaaaggc aggagaaagg cttgtactta
    69901 ctcaaaacta tggcgacatt agtatatata aaaatgcagt aaaagaatac ctaaaatctg
    69961 ttgtagataa tatgtattca cttgataaaa atagtagctt ttgggagcat cagtattata
    70021 agaatgtaaa gattgttgat agtaaacttg aggatatgac tagtaagtta attagtgaag
    70081 aaaaagaaaa catagatatt gtttctactg ttgatatgat acaaggcttg ttgatagata
    70141 tgtatagata aggttataca aggagaaaag ttttatgaat agtaaaaaag aggatatata
    70201 tgaattgaat tttgggcaat taatagaaga aaaatctggt gttatagaag aaaatcaaaa
    70261 tgtttttaat gcaaaagtaa atgtagctgt ttctatagga aatacaacag aaacaataaa
    70321 aaatatatta gatttaaaag aaggctctat aataaaacta agtaagaatg tggatgaaaa
    70381 attagatata tatgcaaatg atagattgtt tgcttatgga gaaagcatta ttacaaatga
    70441 gaagttatct gtaagattat ctaaaataga agattcagat gtaaattagt attttaaata
    70501 gtatcccttt aggctatgat gtatgagttt agctaagggg atatttttat aaaaaattta
    70561 aaatatgcgt gaattatata aatgttttta ttttatgagc gataattaaa ttataagtat
    70621 gtaattttgg aggtgaaact atggatatta aaaatgtaag ttcaaatatt gtagtgaata
    70681 attatttaaa gaatacatct ggtgtaaaaa aagtggaaga agttaaaaaa attaataaaa
    70741 cagacaagat agagctatct aaatttgcaa aggaaatggc aagtgtgtca aatatgagtg
    70801 atgagaatat taggaataaa aaagtcgatg aaataaaaaa tgcattagaa aatggaactt
    70861 acaaaataaa accaaaagaa attgcgaaaa aaatgataga ggatatgcga ggataaagtc
    70921 atgattacag acttaaaagt tataatatat gaagaaaaaa atataattag taagatgatg
    70981 gaattattaa aagaacaatt tgattatata gttgaaaaag acttagaaaa tttaaatatg
    71041 ttaaatccta aactagaaga tattagcagg gagcttgcat ccatagaaat aaagagaaga
    71101 caactttttg gtgatgatat ttcaatgagt gaagttgttg aaaatagtaa tgatagatat
    71161 ttaaaagaaa tatatacaga cttgaaacac attcttgctt tagctaaaaa tcaacaagaa
    71221 tcaaatgatt ctctaataaa gaaagaactt atttttacga aaaaaatgat taatttcata
    71281 aaaccagctg ataagcaaac tgcaacttat aattcttatg gaaatattag aaaataaata
    71341 ttaggaggag aaatatggca ggattatttt ccattttaaa tacagctaat tcaggaatga
    71401 atgcgcacca aaaagcaata cagacaattt ctcataatat aagtaatcta gatacagacg
    71461 gttattctag gcaaaggact gagtttgcta caaatagtcc aatgtatatg cctagtttga
    71521 gtaattcaat tgcaagagga caattaggga ctggagtaca cgtaacggat gtaacaagag
    71581 ctagaaatag tttttatgat taccaattta gagcagaagc tcataagtat ggtaatacag
    71641 tttcaaagta tgactattat aatactatag aaactataat aaatgaacca tcagactatg
    71701 gaatatctgc aggtatagac gactttttta aaggatggga atcattagca aaggatataa
    71761 atagtgatag taaaaaaagt ctagtggtag aaaatgcatc aaatctagca actttaataa
    71821 gtgaaagtta taagaagctt aataagttaa agggagatat agacgataat ataaactctg
    71881 aaataaaaca gataaatgac atgttaaaaa gtcttgaaga tttgaataaa tctattgatg
    71941 ttatatctgg ttctggctct actccaaatg atttacttga tgaaagagat agaatattag
    72001 atgacttaag ctttaaatta gaccttgaaa atagcgatgt taaaaatatg ctttcagatg
    72061 gtaaattaga acttaatgaa ttaaaaaatg cagatggaac ttggaaaaca ggtgtatcag
    72121 gaaccttaca aggcttgttt gaaatgcatg gtaagattga tacatataaa agcgatttaa
    72181 aagatgtatc tgatgggtta gctaagcaga taaatgatgt ttataataca tctgctggaa
    72241 taacagtaac agattttttt ataacttcaa atgtagatgg tgaagatatc ataaaggtaa
    72301 atccagctat aaagagtaac ccaaatgaat taaaacttac tgctgatgag gcttcaaaga
    72361 ttgctaagtt aaaggatgaa aaaatagata ttggggtggc tggtggaaaa gtaagtacaa
    72421 taagtgacca ctataaagcc tttgcagaat cagtaggttt agattctcaa aaagtgaatc
    72481 aagatgaagt gaatcaacgt aaaattataa ataatattga taactcacga atgagtgttt
    72541 caggcgtatc tttggatgaa gaaatgacag agcttataaa aatacaacgc tcctatcaag
    72601 ctagtgcaaa agttatgtca acagctgtgc aactgttgga tgttgtaata aatggaataa
    72661 tttaatagaa gggggaattt ataatgagag ttagtacagg tatgatgtct agcaactatc
    72721 taaactcact acaagataat ctacaaagat tagataaggt taatagacaa gttaatacaa
    72781 cgaaagaaat aaacaagcta tcagataatc catataaggc aataaaaata ttgaactcaa
    72841 aaagtgaaat aaaaactatg gagacttatg ttgagaattg taaagataca gggaattggt
    72901 tagaaactac tgatactgca ttagatcagc ttggaaaatt attatcggac ataaagaaaa
    72961 ctttggtggc aagtggtgat ggtgcatatt cagatgatga gctaaagact cttagtaatg
    73021 aaactaatga aaagatgaaa gaaattgcaa atgccttaaa tgcaacacat gaaggaaagt
    73081 acatattttc aggttcaaat acaggtgtac cacctgttga atgtatagat aatgctgacg
    73141 gttcagtgag cttaaagttt aattctagtt taaatcttaa taaattaaat gactctttga
    73201 gtatggatat agctcaagga ataagtgtag attataatgt taaattgagt agccttggat
    73261 ttgacccaac aaagactgac ccatttgaag agttaaataa tatatcaaag aaattagcaa
    73321 atccagatgc tgatgctata aaagagctga caacaacttg tttaggcgac atggaacaat
    73381 taatagaaaa tacagtaaat gttaggtcta tatatgggac aaaagcaaat acagtagagg
    73441 ctatgaagga aaaaaatgat gatagtttga tacagttaaa ggatattttg tcacaaaatg
    73501 aagaaataga ttatggagaa aaactcgttc aattaaaggc agcagagtta acttatcaag
    73561 cttcactaca aacaggagga aagttattta atgtatctat attagattac atatagtaaa
    73621 ataacgcaga tatgatgaag gttacattaa aaaaaggtat attaggtttt gaaaatttaa
    73681 aagaatatga gcttttagat atagaagata atgattcttt aaaagaattt aattctactg
    73741 aagaagaagg tataggattt gttgttgtat ctccatttga gattatcaat gaatatgaaa
    73801 tagttttaaa tcaggaaaca atagaaaaac tagaagtgaa atctccaaag gatgttgtac
    73861 tatttaatat aattactctt ggtcagacat ttgaagaatc aactgtgaac atgaaagctc
    73921 ctatagtgat aaatataaaa actaattttg gaatgcaaat aattttacag gatgataaat
    73981 attcaataag gcatccatta ttgagaggtg ataatggatg ctagtaattt caagaaaaaa
    74041 agatgaagca gtacttatag gagaaagcat agaagtaaaa attgtagggg tagatggaaa
    74101 caatgtgaaa ctagctatat cggcgcctaa caatataagt atattaagaa aagaaatata
    74161 cgaaaaagta aagagtgaga atataaaagc tacaaataaa aatataaaaa ttttaaagtc
    74221 attaaaataa taagcttgga ggaagtaata tatgtatgga gaaaatcctt ataattctta
    74281 taaacaaaat gctgttttta tggcatcaaa ggaacaattg ttacttatgc ttgttgatgg
    74341 agcagtaaaa tataccaaaa tagccagagc agctatctta gataaaaata cacagaaagc
    74401 gcatagagaa cttgtaagag ttcaggatat atttacagaa ctaatggtta cattagacca
    74461 aaatgcagga caatgggcaa aggatatgta caaagtttat gattttgtaa gatatgaact
    74521 ttcaagagcc aatattagaa aagacatcca ggtaatagat aatgtgttgc ctgtaataga
    74581 acaaattaaa gacacatggc atgaagctga taaaaaaagt aaagaagaaa gaagtaggta
    74641 caaataatgg aattaaattt agctgaatta gataagttat caaaagagga attactattg
    74701 atgcttgtag atggcacagt aaaatatacc aatatatcca aagaagctct tttaaataac
    74761 gactatttga aagcacataa tgaacttata agagttcaaa atatatttac agaactaatg
    74821 actacattag accaagatgc aggtcaatgg gcaaaggata tgtataaagt ttatgaattt
    74881 ataaaatctg aattagcaat agctgatgaa aataaagata ttaaaataat tgatgatata
    74941 ttgccaatag taaaacaaat tagagataca tggcatgaag tttacaatca actaaaaata
    75001 taattagatg gagggataaa ggtatgtcaa gtataagtcc tataagagtt acaggtcttt
    75061 caggaaattt tgatatggaa ggcataatcg aagctagtat gattagagac aaggaaaaag
    75121 ttgataaagc aaaacaagaa caacaaatcg ttaaatggaa gcaagaaata tatagaaatg
    75181 ttatacaaga atcaaaagat ctttatgata aatatctaag cgtaaattct cctaatagta
    75241 tagtaagtga aaaagcatac tcttctacaa gaataaccag ttctgatgaa agtattatag
    75301 tagcaaaagg ctcagctggt gcagaaaaaa taaattatca atttgcagtt tctcaaatgg
    75361 ctgaaccagc aaaatttact attaaattaa attcaagtga acctattgtt cgacagttcc
    75421 ctccaaatgc cagtggagct agttctttaa ctataggaga tgtaaatata ccaatatctg
    75481 aacaagatac tacaagtact attgtaagta agataaactc cctttgcgca gataatgata
    75541 taaaggcttc ttatagtgag atgacaggtg aattgattat ttcgagaaaa caaactggtt
    75601 cgtcatcaga cattaattta aaagtaattg gaaatgacaa tttagctcag caaattgcta
    75661 atgataatgg tatcacattt gcaaatgatg ctagtggaaa caaagtggca agtgtatatg
    75721 gaaaaaatct agaagctgat gtaactgatg aacatggaag agtaactcat ataagtaaag
    75781 aacaaaattc atttaatata gataatattg actataatgt aaattcaaaa ggaactgcaa
    75841 agttgacttc tgtcactgat actgaagaag ctgttaaaaa tatgcaagca tttgtggatg
    75901 attataataa actgatggac aaggtctatg gtttagttac tactaaaaaa ccaaaagatt
    75961 atccgcctct tacagatgcc caaaaagaag atatgacaac tgaagaaata gaaaaatggg
    76021 aaaagaaagc taaagaaggt atacttagaa atgatgatga gttaagaggt tttgttgaag
    76081 atattcagtc tgcatttttt ggagatggaa aaaatattat tgcattaaga aaactaggta
    76141 tcaatgaaag cgaaaattac aataaaaaag gtcaaatatc atttaatgca gatacttttt
    76201 caaaggctct tatagatgat agtgataagg tatacaaaac actagcaggt tattcttcga
    76261 attatgatga taagggaatg tttgaaaagc taaaagatat tgtatatgaa tattctggaa
    76321 gttcaacttc taaacttcct aaaaaagcag gtatagaaaa aactgcttct gctagtgaaa
    76381 atgtatattc aaaacaaatt gcagagcaag aaagaaatat aagcaggtta gttgaaaaaa
    76441 tgaatgataa agagaaaaga ctttatgcta aatattcagc cttagaatct ttgttgaatc
    76501 agtattcttc ccaaatgaat tatttctcac aagcacaggg taattaatta tggataaatt
    76561 aaaagaaaaa ttaaatttat ataaagatat atctttacaa attataaatt tgattgaaaa
    76621 ggaagaatat ataaagataa gtagtaagtt aggtgaaaga caagagatta taaatagtgt
    76681 aagtgaaatt gatagaaatg attttataca gctttataat agaatggaat taattgaaat
    76741 tgatagtagg ataagagata ttttacaagg acaattatta gaagtaaaaa aagaattaca
    76801 tgagtataag cttactaaac aagtgaacac aatgtattat aacttaaata gagaaaaagt
    76861 aaatattttt aataaaaaag tataaagtta tgtaccatct tgtccgatta tataaatgaa
    76921 gaattaataa aaaagattaa aagtagaaat gacaaggatg tcaactatac taaggagggt
    76981 aaaataatga gagttaatac aaatgtaagt gctttgatag caaataacca aatgggaaga
    77041 aacgtaaatg cacaaagtaa gtctatggag aagttatctt ctggtgttag aattaagaga
    77101 gctgctgatg atgctgctgg gcttgctata tctgagaaaa tgagagctca aataaaaggt
    77161 ttagaccaag caggaagaaa cgttcaagat ggtatatctg ttgtacaaac agcagaaggt
    77221 gcattagaag aaactggtaa tatactacaa agaatgagaa ctttatcagt acaatcttca
    77281 aatgaaacta atactgctga agaaagacaa aagatagctg atgagttgtt acaattaaag
    77341 gatgaagttg aaagaatatc aagctcaatt gagtttaatg gtaagaaatt acttgatgga
    77401 agttctacag aaataagatt acaagttgga gctaattttg gaacaaatgt tgcaggaaca
    77461 actaacaaca acaatgaaat aaaagttgct ctagtaaata cttcaagtat aatgagtaaa
    77521 gcaggtataa caagttctac aatagcaagc ttaaatgcag atggaacttc tggaacagat
    77581 gcagctaaac aaatggtgtc tagcttagat gtagctctta aagaattaaa tacatcaaga
    77641 gcaaaattag gggcacaaca aaatagacta gaatcaactc aaaacaactt aaataatact
    77701 atagaaaatg ttacagcagc tgaatcaaga ataagagata cagatgttgc ttcagaaatg
    77761 gttaacttat ctaaaatgaa tatattagtt caagcatcac agtcaatgct tgctcaagct
    77821 aatcagcaac cacaaggagt tttacaatta ttaggataaa ataattttgt atattggata
    77881 tagaagaaag ggtaaggctt tgctttactc ctttcttttt ttacaaatat acttttgaaa
    77941 ggaaaatata tatgttactt agtatagtta tgattgttaa aaatgaagaa aaaatacttg
    78001 aaaaaacttt aaaatcatta accacattaa gaagttctat agagagtgaa cttataatag
    78061 ttgatacagg ttctacagat gatactataa atatatctag gaaatacacg gaaaatgtgt
    78121 actttcataa ttggaataat gatttttcta gtatgagaaa tatatcaata tcctatgcta
    78181 aaggtgaatg gttacttata ttagatgcag atgaaatact aattgattct tcaactattg
    78241 tgaaattttt taaagatggt cttgataaaa aatttaattc ggcctcaata caattaaaaa
    78301 atctttactc atatgataaa aaattatatg gatattgctc agtgcttaga ctttttaaaa
    78361 acatcgattt tagataccat ggtaaagtac atgaacaacc aatatacaaa aaccctatat
    78421 ttaataatgt tgctgatttt gaacattatg gatatttgtt tgaagatgaa gaaataagat
    78481 taaataaagt aaaaagaaat gaaaaactgt tatttgaaga attaaaagag aatgataatt
    78541 ctccatatac aaattatcaa ttagggaaaa attttattat attaggaaaa tatcatgagg
    78601 ctttatacta tcttgagaaa tcttatgaat tatattctaa actagaatcg gcacctggtt
    78661 acttgataac aagtcttgta aaaacatatt tatatttagg aaagcataag aagtgtgaaa
    78721 aattgtgtct aaagtatatt aagaaagaca tgaataatat tgatatatat tattatattg
    78781 cacaagcaca agtagattta gggaagtatg aaaatagtat agattcgtat aagagatata
    78841 tttatttgtt agataattat gaaataagta cacaagcaaa tagtttattt tcagacactg
    78901 atactgtagg gcttagggat gaagctatta ttacactgat aaagatttat tataaacttg
    78961 aaaaatatga gtctgtaatt tcagagtaca ataacattga ggatatggaa aagaagaaga
    79021 atgtgtactt tagcttattt atgtccctat acaaattgaa cagatttgaa gatataaaaa
    79081 actattataa agaagtttca aattctaaaa ttgaaaaaaa tagtttttat aaaaatatag
    79141 aagaagttat aaataatatt aaagatgatg aaaaagagca tgtatataaa atcctttgtg
    79201 acattgaagg taattatggc attttaaatc agataaggat aaataaatgt gtatctatag
    79261 ataagtgtaa agaaatactc aatgaagaaa aagaaataat ttatgcatat attataaaag
    79321 tagcttttga agataagatt gatttactag atatttttta tgaaatggaa tatgtatgga
    79381 tagagaaata cctaaaatat cttttagcac tagaaagaag ttttaattta gtactatata
    79441 agtacataat tagtcgtccg aatacatcag atataaaaaa gataagagta tataaagcta
    79501 tatctaaagt agttttagaa agtataagtt taagtgatga aaaatataag gagatttttt
    79561 atctttatat aatgtattct tataagtaca taagatacat atatagaaat ttaagcgatt
    79621 ttgaattaat aaaatttgtt tgcaatgatt tagataagtt tactatagaa tttaagcatc
    79681 tacttgacat taaaaataaa gtaaatgatg ctaatgaaaa attagagtat atacatagta
    79741 tgaggaaatt actaaatgag tatccttttt ataataaaat aataaaaata cttataagtg
    79801 aattagaaga aaatataaaa gaaagtgaag aatttaagga tttaaaagat agttttatta
    79861 ttagtataga aaatatgatt gaaactggca aaataaatga tgcgaaatca ttggtagatg
    79921 actattcaaa aacatttatg gatgatgtaa aaattttaaa tataaaggga attttatata
    79981 tgtttgaaaa taagcttgat aaagctgatt ttatgttaaa aaaggcatta tcattagatg
    80041 tagaaaatga agatactata tataatatag aatacttaaa aagtttaaga taagtcaaaa
    80101 atgggagaat tgaagaatga atacaccaat agtggttaat gaaaaatcta aagatataat
    80161 aaaagattgg caatatacgt atacaaacga agatataaaa tttacaagca taataatatt
    80221 gacatataat caaatagaat atactaaatt atgtattgaa agtattagga agtttacccc
    80281 aaagaataaa tatgaaataa taataattga caataactct tctgatggaa cagttgagtg
    80341 gttaaaggga caatctgaca taaaatctgt atataataac aaaaacctag gatttccaaa
    80401 aggatgcaat caaggtattg agttggctac tggtgaaaac atattgttgt taaataatga
    80461 tgtaatagtt actccaaatt ggctttataa tttgaataaa gctttatggt ctcaagataa
    80521 tataggtgct gtaggtccta ttacaaatgc atgttcgtac tatcaacaaa ttgatgttga
    80581 ttataaatca attgaggata tgtttatgtt tgcacacaaa ataaatacat ctaatattaa
    80641 cctatggaaa tatagattaa agttagttgg attttgcatg ttaataaaaa aatctgtgct
    80701 ggataatgta ggggttttag atgaattatt cacacctgga aattttgaag atgatgattt
    80761 atcttttagg atgctagagt caggatataa gctattatta tgccaggata cttttataca
    80821 ccattttgga agtgtatctt ttaaagaaaa tcgtaataaa tatacagata taatgtatat
    80881 taatagaaga aaatttgaaa ctaagtgggg atttaatcca gaatatagtg gaatgataag
    80941 aacagatttg atttctaaaa tagatgatag tttggaggca aatattaatg ttttagaaat
    81001 aggctgtggt ataggggcta ctcttttaga aataaaaaat atatataaaa atgcatcaat
    81061 atatggaata gaaattagtg agtcagcagg taaacttgca aagtatagtg cagatgtact
    81121 tatagcagat atagaaaaag taaagttgga ttatgaaaaa gatttttttg attatataat
    81181 attgggagat gtacttgaac atttaactga cccatggaag atagtcaatg aactgaaaca
    81241 atatctaaag aaggatggtt gtttgatatc tagtatacca aatattatgc atgtttctgt
    81301 tttaagaaac cttgtgttag gtaattttac atatgaagat tcaggaattt tagacaagac
    81361 tcatttaagg ttttttacat taaatgagat aacaaaaatg tttaatgata gtaattacat
    81421 aataaatagt gttacagcta ctagtatgcc actttcggaa attgataata gattcattga
    81481 tacaatgtgt aaggaaagct gtaaagaaat gagacaacag tacgaatctt atcaatatat
    81541 agtaaaagcc actaaaagca tagatactaa aagatattct agtattagta tggttaattt
    81601 aaaatacgct ttaatgagaa ttgataatga attagatgta gatagtaatt taagttatat
    81661 atttgataat tataatataa ctgaaccatg ttttgttgat gatattgaat atttagttga
    81721 tacgtttgtg ataaataaag caactctatt aaatagatta ggagttgagg catttaacag
    81781 aggtttagga gattttagta taaacatgtt tatgacagta ttagagatgg atagagatga
    81841 tattgattca atatataata taacaagtgt attatgtgaa ttagaagaat ttgatactgc
    81901 ttacaactta attaaaaata gtagcaaaaa agtacagagt gaaagtgaca tacaagatat
    81961 actttatttt attgagggga agagatatga ataatgataa gatatgtttt ataacctgtg
    82021 taaatgatga aagactttat gaggaatgtc ttgtatatat aaatagccta gacattccta
    82081 aaaactttag catagaaaca gtagctttaa gaggagccga ttctattgcc tctgcttata
    82141 ataaagctat gagagaaaca gattctaagt ataaggtata cttacatcaa gatgctttta
    82201 taattaataa aaatttcata tatgacattt tagagatatt taaaaaaaat acagatgtag
    82261 gaatgattgg tgtagctgga gtaaaagata tacctgtgaa tggaatttgg tgggattctg
    82321 ataaaaaagc agggaaagta tatgatagcc atacaggtaa aatggatatt tatgaattta
    82381 gtaactttga agaatgtttt aatgaagtta tggctataga tggattaatt atgattactc
    82441 aatatgatgt attttggaga gaggataagt ttgatgggtg gcatttttat gatttgtcac
    82501 agagtatgga atttagacaa aataaataca aagttattgt accaaaacaa aataagcctt
    82561 ggtgtatgca tgattctgga gtagcaaata taaataatgg atatgatgaa tataggataa
    82621 aatttgtaaa agagtacata aatcttgatt tatatagaga aaatttttat gaatttgata
    82681 agaagaaagc aagtaccata cttaagagta ataagcatgt aatggattgt atgaaagagg
    82741 agcttacaga acaattaaga ttaaagaatt ataaggatgt tttagatatt gtttctaaaa
    82801 ttgctcattt ttctgttttt aatcatactg gcttgtattc ttgtgaaaaa tgtgagagag
    82861 cattgctaga atgtgcaaat aatttaccag aaatagaaaa tacgaaatta tttacaaaaa
    82921 aagatttaaa aagaagaaaa gtattacatg ttttaagtga aggatattca acaggagggc
    82981 atacaagact agttaaaaat tggattgaga ttgacaaaga ttctgttcat tcagttgtaa
    83041 ctacatggca atcagataca ctgccagact ggttattaaa agcaatagat gatagtggtg
    83101 gcgaagttat atctttggat ttaatttcag atgattattt aaaaagagct gtagctttga
    83161 ggaaaatagc ttatgactgg gctgatatag ttattttata tgttcatatg tgggatacaa
    83221 tacctgttgt tgcttttgga gttgatggga aaatacctat tttacatgtt aatcactatg
    83281 atagtacttt ttggttaggg acaagtattg cagatattgt cattgatttt agcgaagcta
    83341 gtcaattaat tacattagat aaaagaggca tagataaatc tgaaatatta ccaatgccat
    83401 taaaagaaaa agaagtattt tcaaaatctg aagttagaaa acgatataat ttggaggatg
    83461 atgtgacaat aatattgact attgctagtg aaagaaaata caatagtgta aatgatatta
    83521 attactttaa aattgctaaa acattgattg aaaatacaga taatacaatt attattgttg
    83581 taggagttga tacagagaat ctctattgga aaactttaag taacgttaca gataatagag
    83641 ttatatgttt tggaacaaca gcaaatatag acgattttta taagatttcg gatatatacc
    83701 tagagtcttt catggtaggg agtcatactt caaaattaga tgcaatttta tatgatttaa
    83761 ttcctgttaa gtttaaaaat gaagtttcac caatttttac aaatatgtgg aattttatag
    83821 ataagtttga ttataagaat ataaaagagg ttatagacat gataagaagg tacaatacta
    83881 gtgaatttga cagggataag ataaaagaaa aacaatcaga aataaaacat tttgttatag
    83941 ataaacactg tattgaaata aaaaactata tagacaaaat atataaagag gctaatcatc
    84001 ataaagttaa gtatgattta tataaaaatg atgaaatcga agactatcag ctttttgttg
    84061 cattatatgg ttatatggta aaaaataaaa acatgtcata ggtgataaaa tgaacaatat
    84121 tcatatcaat aaatttgaaa aaagctgtga aaaaaactgg gattattttg tagaaaataa
    84181 atctataaat ggtacatttc tgcaaactag aaatttcctt aattatcatg aagaaggaaa
    84241 attcactgac cactcattaa taatatataa aggtgaagaa atactagcag tcgtacctgc
    84301 atgtgaaact tatgaaaatg gtgaaagagt atttttttct catttaggaa gcacttttgg
    84361 aggtattata ataagaagtg gttttaatga tattaggcat gtaaatgcta ttacaaataa
    84421 gttagaaaca tatttacagg aacaaagttt caataaagta tatttaaaaa atacatcaag
    84481 aatattttgt aaagaggata cttcattact agaatatttt ctatttaaga ataattacat
    84541 gttttatgat gaattaagta tgtttttaga attaagtaag tataaaaaag atatattagc
    84601 taattttaga tatagtaaaa gaagatattt taaatattct ttgaagaata atcttacctt
    84661 taaaagattg tatagtgatg aggatatagt ttgttttttt aatttacttt ctaattgttt
    84721 agatagtaaa ggagctaaag taatacattc agtagaagaa cttttggagt ttaaaaataa
    84781 tagattaaaa gatattgtag aattttatgc agtatatatt gatgacatta tgatttgtgg
    84841 gagcatggta tttaactttc aagaaagagt ttatcatact caatatctag catcaaattc
    84901 gacatataat aaatattatc caatgatatt tttatactat aatctaataa aagatgcttt
    84961 agagagaaat tttaagtatc tttcttttgg aattagcact ctaaatagag gcaaatactt
    85021 agacgagggt ttagctacat ttaaagaagg ttttggttca agtgcaattt gcaacagaac
    85081 atactataaa aatataaata agtgataatc atgttttata gagtttttag agtatagtaa
    85141 atatctagta ctctaatatt acataaaaat aattagttta taaagaaggt ttgtatatga
    85201 aaagattaat gattttaggc tcaattaagt attttgagaa tattgttatg tcagctaaaa
    85261 aagagggaat atacacaatt gtttgtgata atagaattga tactcctgcg aaaaagattt
    85321 gtgatgaagc aatagatgtt gatgtatttg attttgataa aataaaaagt atagctatag
    85381 ataaaaagat agatggaatt ttaactggat ttacagattc tttaatgaaa ccatatgttt
    85441 atattgcaaa tgaactaaat ttaccatgtg tgatttcttg caatcaactt gaatctgtaa
    85501 ctaataaggc tattatgaaa aaatatttta aaaataatgc aatacctaca actgattatt
    85561 gtattattga aagtctaaaa gatttagaaa aaatacaagg attaaatttt ccacttgtaa
    85621 taaaacctgt tgatggttat ggttcaagag gtgtatattt tgtatcaaat atagaagaat
    85681 taatagaaaa atttgaatat tctaaggaag cctcacaaga tggacaagta ataattgagg
    85741 aattttatga aagtgaggaa atacaaggac tagcttgggt tcataatgga gagtcacatg
    85801 tattttatat tggagataga gagcttgtaa atatacatac aggaagagct ggaaaaccag
    85861 atagattact ttatccatca aagtattgtt ttcaatatga ggaagaaata aaatctatat
    85921 atcaaaatat aacacaggct tttgatataa aaaatggacc tctttatgta caaatgttag
    85981 tgggagcata tggaataaag gtatctgaag taatgccaag attacctgga ggttgtgact
    86041 atatggctat ttctcaaata acagatttag acataggaag tttatttgca aactttagtg
    86101 tgaataatga agtaaatttt gatgaaataa agaaatataa tatgcattta tcaaaatgtg
    86161 tatatgcatt accaatatac ataagacctg gaacaataaa aaagataaat aatatagata
    86221 aaatagaaaa cttagattat gtcactcaat ttctattatt agtaaaagaa ggagatacaa
    86281 taggattata tgaggatgag agacaggatt gtggaagagt ttatggaata gcaaataata
    86341 tatttgatgc aaatataaag aagaaatgta ttcatgaaat gatagaaata tttgatgaaa
    86401 ataatgaaaa tatgatagaa aatttttaaa taagggagta tgatagatat gaagctaata
    86461 actcatgaac aaattatgtc attaaacatt tctcagaaac aaggatatga atggataaaa
    86521 gaatcttttt taacaaaaaa agattgtcaa ttaccaccaa aaataagcat ggtagaagaa
    86581 ggtcatgtat tttacaatgt aatgccgtcc ttaaatcata accatatgat tggtggaata
    86641 aaaatggtta caagattgcc agggagaaat ccaagtttaa attcagatat atttctatac
    86701 aatatgaaag atgctaaatt aaaggctatt ttggatggta attatattac agcttttaga
    86761 actgctgctg ttgctggttt ggctattgat acttttgcta aaaaagattt taatactatt
    86821 tctattatgg gtttaggtgt aactgcttct gctataatga atatgctttc gtatactctt
    86881 aaagataaaa atataaatat aaagttactt aaatataaag accaagcaga gtcatttata
    86941 aaaaagtatg aaaaaaatga acaatttagt tttgaaatat gtgatacaca tgaagaactt
    87001 attgtagatt cagatgtagt tatttctact gtgacatata cagatgaata tttatcagaa
    87061 tttaaatggt ttaaaaaagg tgctttatta ttacctgtac atgttatggg atttggaaat
    87121 gttgattatc tatttgataa agtatattta gatgattata atcatttgaa acatctagaa
    87181 aatatagata gatataaata ttcttgtgaa ttttataatg ttttaagtaa acaagctaaa
    87241 ggaagagaaa atgatgatga gagaataata tcttacaata taggtttgtc aatacatgat
    87301 atattatttg caaacaaaat ttacgaattg tgtgaaacac taaattgtga agagatagaa
    87361 ttaaaagaac caaaagaaaa atattggata tagtttattt cattcatatt tacaataatt
    87421 tattgtaaat atgaatatga agtaatatat tgttagaaaa ttagcatgaa taggatagat
    87481 aaatttatgg ataaatataa tttaattaag ttcttatcta ttggaaacga atatatagga
    87541 aatttagttg cattagaatc aaataaagca ataccttttg atataaagag agtttattac
    87601 atatatgatg taccaaacaa tgtaaagaga ggatttcatg cacacaaaaa cttggaacaa
    87661 gtactagttt gcctaaatgg aagtgtgaag ataaaatgtt atgatggtgt aaaagagagt
    87721 atatttaatt tacataaaaa tgatgttgga ttgtatatag gaacgggagt gtggcatgag
    87781 atgtttgact ttgatgaaaa aactgtttta atttctatag catctgaaca ttacaatgaa
    87841 gaagattata ttagagacta taaagaattt ttaaagtatt taaataatat gtagttatta
    87901 tacagttagt gatgtatttt cttaattaaa taaatttaag atagccatat agagaataaa
    87961 tagattagga tgtgaattta ttgttggtta aatttaataa tttattaaaa cagttccaaa
    88021 ctcataaaga agaatatgaa cagaagatta aggatgtaat ggaaagtgga tattatatcc
    88081 ttggaaatga agtaaggcat tttgaagaag aatttgctag ctatgtaggt agcaaatatt
    88141 gtgttggttt agccagtggt ttagatgcac ttataattgc ttttagagca ttaggaataa
    88201 gtgaaggtga tgaagtaatc gtgcaatcaa atacatatat tgctagtgtt atgggaatca
    88261 gcataaatgg agcaacacca gtatttgtag aaccaaatga atattataat atagattcat
    88321 ctaagataga agaaaagata aatagcaaaa caaaagctat attagtagtt catttatatg
    88381 gtcaagcaag taaaatgaaa gatatacaag aattatgtga taagtataac ttgtatttaa
    88441 ttgaagattg tgctcaatct catggagcta aatatgatgg aaaaatgaca ggaacatttg
    88501 gtgatatagg ttgttttagt ttttatccaa gtaaaaattt gggtgcattt ggagatgcag
    88561 gagctatagt aactagtaat gaggaaatag ctgataaagt gaaaattctt agaaactatg
    88621 gttcagaaaa gcgatattat aataaatttg tcggatataa ttcaagattg gacgaaattc
    88681 aggcaggttt attaagagta aaacttaaat atctaaatga aattgaaatt gaaaaatcaa
    88741 aaatcgtaga tagatatctt aatgaaatta ataatcccaa agtcatactt ccaaagatag
    88801 aaaataattg tactcatgta tggcacttat ttgttttaca agttgaaaaa cgagatacat
    88861 ttatggaata cttaaagaaa aatggtatag agtctataat acattatccg ataccaccac
    88921 atctatctga agcatatgct tatttgggat ataaaaaggg gagttttaat atagctgaga
    88981 actattcaga taaagttgtt agtatacctt tatttgtcgg tatggaagat gaagaagtta
    89041 gttatataat taaaattata aatgaatatt aaactaatca taataatatc aaaaataaat
    89101 tttctatata tcatttattt aaatttcgtt aattgacatt tttaaatatt gatatattgt
    89161 acaaataaaa ttgaaatata tggaagaata tagaataaag atgagatttg tctaatattt
    89221 ttataaatta aaaatatttt caaagagttt attataaaat tgtagactat agtgtttata
    89281 atctttgtaa ttattggtaa ctaaatttaa aaaataaaat atttaattat acacaaaaaa
    89341 gatatttaaa aaatttgtta tttattgtat acttaagtta aaactaaata ggcaaatcta
    89401 gagaaatcta gtgacgcaaa gctatagggg ctaaggtttg tatacacaaa ctatgtcagc
    89461 cagttgccaa aaagagttct aggtatattg tatacgtagg aagagtctag gatgactgcc
    89521 tttttggtgg tcattttgtt atggaaaaaa tcacattatg tagtaaaaaa cacctataat
    89581 aacatattat accaaatata atttaaaata aagataaatt atctataaaa gttactattt
    89641 tacaaaaaat gacttcttta ttcatccaaa ttaattacat ttctattaca ttaatataat
    89701 aatgtatcac tttggtaaga aaactaatat tattttcgta aatcctaa
//
LOCUS       DAEQJM010000012        81167 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.012, whole genome shotgun sequence.
ACCESSION   DAEQJM010000012 DAEQJM010000000
VERSION     DAEQJM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 81167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81167
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.012"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            86..1144
                     /locus_tag="KRQ43_001062"
     CDS             86..1144
                     /locus_tag="KRQ43_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HBH2741432.1"
                     /translation="MIVCNNPGTWMRMYPQLRHAVWHGVTLADFAFPFFVISLGVTIP
                     ISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNPDLNSVRILGVLQRMGLVY
                     FVTSLVYLLLKKLNVGSTATIITFLCIATFIIVGYYILAKPYGFELEGSLAQLVDLHF
                     FKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENIGEYKKFFKILVMSIILLI
                     GAFIFNQYFPFNKRLWSSSFVLLMAGSYGMLLSIFYFICDIKNKSKIFTPIIALGSSP
                     IFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELITPWAGTTWDSLIFSLLYVL
                     FWVIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="KRQ43_001063"
     CDS             1398..3422
                     /locus_tag="KRQ43_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH2741433.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAGT
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="KRQ43_001064"
     CDS             3642..4328
                     /locus_tag="KRQ43_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBH2741434.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="KRQ43_001065"
     CDS             4423..5478
                     /locus_tag="KRQ43_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HBH2741435.1"
                     /translation="MIKKISTILSLVLLISISSTIEVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGIKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTAKLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7152
                     /gene="murJ"
                     /locus_tag="KRQ43_001066"
     CDS             5593..7152
                     /gene="murJ"
                     /locus_tag="KRQ43_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH2741436.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDDKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRRR"
     gene            7194..8900
                     /locus_tag="KRQ43_001067"
     CDS             7194..8900
                     /locus_tag="KRQ43_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH2741437.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNDTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8922..9995
                     /locus_tag="KRQ43_001068"
     CDS             8922..9995
                     /locus_tag="KRQ43_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HBH2741438.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEYISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10007..10729
                     /locus_tag="KRQ43_001069"
     CDS             10007..10729
                     /locus_tag="KRQ43_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH2741439.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10745..11902
                     /locus_tag="KRQ43_001070"
     CDS             10745..11902
                     /locus_tag="KRQ43_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBH2741440.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNIDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTIFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11905..12744
                     /locus_tag="KRQ43_001071"
     CDS             11905..12744
                     /locus_tag="KRQ43_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH2741441.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNEDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYTFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12759..13934
                     /locus_tag="KRQ43_001072"
     CDS             12759..13934
                     /locus_tag="KRQ43_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBH2741442.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13963..14712
                     /locus_tag="KRQ43_001073"
     CDS             13963..14712
                     /locus_tag="KRQ43_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH2741443.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYKRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14734..15642
                     /locus_tag="KRQ43_001074"
     CDS             14734..15642
                     /locus_tag="KRQ43_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH2741444.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15690..16442
                     /locus_tag="KRQ43_001075"
     CDS             15690..16442
                     /locus_tag="KRQ43_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH2741445.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16420..17763
                     /locus_tag="KRQ43_001076"
     CDS             16420..17763
                     /locus_tag="KRQ43_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HBH2741446.1"
                     /translation="MPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLAEVGNENVV
                     CVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDVDVILIAVG
                     TPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYINRNLKNNVK
                     VELASNPEFLSQGTAVKDTLYASRIVIGVESEWAREILEEIYKPFNQPIIVTNRNSAE
                     MIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLKAGIGYGGS
                     CFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQDMKVAVLGL
                     TFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYADSVDDAIE
                     DAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEYYSIGR"
     gene            17769..18860
                     /locus_tag="KRQ43_001077"
     CDS             17769..18860
                     /locus_tag="KRQ43_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH2741447.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18944..20857
                     /locus_tag="KRQ43_001078"
     CDS             18944..20857
                     /locus_tag="KRQ43_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH2741448.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNSELKKVAVAIIDDDKDKIGRIIHNVKIVGTTSDIKAVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21056..21763
                     /locus_tag="KRQ43_001079"
     CDS             21056..21763
                     /locus_tag="KRQ43_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH2741449.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYRWGATGPNAFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            22065..24176
                     /locus_tag="KRQ43_001080"
     CDS             22065..24176
                     /locus_tag="KRQ43_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HBH2741450.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTAL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24374..25339)
                     /locus_tag="KRQ43_001081"
     CDS             complement(24374..25339)
                     /locus_tag="KRQ43_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH2741451.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25624..26580)
                     /locus_tag="KRQ43_001082"
     CDS             complement(25624..26580)
                     /locus_tag="KRQ43_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH2741452.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVDIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26948..27736
                     /locus_tag="KRQ43_001083"
     CDS             26948..27736
                     /locus_tag="KRQ43_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH2741453.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVDDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27859..28329)
                     /locus_tag="KRQ43_001084"
     CDS             complement(27859..28329)
                     /locus_tag="KRQ43_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HBH2741454.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28468..29112
                     /gene="uppS"
                     /locus_tag="KRQ43_001085"
     CDS             28468..29112
                     /gene="uppS"
                     /locus_tag="KRQ43_001085"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HBH2741455.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29155..30060
                     /locus_tag="KRQ43_001086"
     CDS             29155..30060
                     /locus_tag="KRQ43_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH2741456.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTSQQQKVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30375..31922
                     /locus_tag="KRQ43_001087"
     CDS             30375..31922
                     /locus_tag="KRQ43_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH2741457.1"
                     /translation="MNKNSMTKIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIMILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIINLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31925..32323
                     /locus_tag="KRQ43_001088"
     CDS             31925..32323
                     /locus_tag="KRQ43_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH2741458.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32363..34096
                     /locus_tag="KRQ43_001089"
     CDS             32363..34096
                     /locus_tag="KRQ43_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBH2741459.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGVGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKKILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34328..35539
                     /locus_tag="KRQ43_001090"
     CDS             34328..35539
                     /locus_tag="KRQ43_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH2741460.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35731..35991
                     /locus_tag="KRQ43_001091"
     CDS             35731..35991
                     /locus_tag="KRQ43_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBH2741461.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            36344..38056
                     /gene="ptsP"
                     /locus_tag="KRQ43_001092"
     CDS             36344..38056
                     /gene="ptsP"
                     /locus_tag="KRQ43_001092"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBH2741462.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASIHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(38848..39513)
                     /locus_tag="KRQ43_001093"
     CDS             complement(38848..39513)
                     /locus_tag="KRQ43_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741463.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            39857..41287
                     /locus_tag="KRQ43_001094"
     CDS             39857..41287
                     /locus_tag="KRQ43_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH2741464.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKALKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEDQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEEICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            41655..42233
                     /locus_tag="KRQ43_001095"
     CDS             41655..42233
                     /locus_tag="KRQ43_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBH2741465.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKFVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            42263..42409
                     /locus_tag="KRQ43_001096"
     CDS             42263..42409
                     /locus_tag="KRQ43_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBH2741466.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            42714..44093
                     /gene="scfB"
                     /locus_tag="KRQ43_001097"
     CDS             42714..44093
                     /gene="scfB"
                     /locus_tag="KRQ43_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HBH2741467.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            44122..44619
                     /locus_tag="KRQ43_001098"
     CDS             44122..44619
                     /locus_tag="KRQ43_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBH2741468.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            44917..46581
                     /locus_tag="KRQ43_001099"
     CDS             44917..46581
                     /locus_tag="KRQ43_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBH2741469.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            46594..49044
                     /gene="recJ"
                     /locus_tag="KRQ43_001100"
     CDS             46594..49044
                     /gene="recJ"
                     /locus_tag="KRQ43_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBH2741470.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            49057..49569
                     /locus_tag="KRQ43_001101"
     CDS             49057..49569
                     /locus_tag="KRQ43_001101"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBH2741471.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            49643..51850
                     /locus_tag="KRQ43_001102"
     CDS             49643..51850
                     /locus_tag="KRQ43_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBH2741472.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            51875..52324
                     /locus_tag="KRQ43_001103"
     CDS             51875..52324
                     /locus_tag="KRQ43_001103"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBH2741473.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNASRPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            52339..52953
                     /locus_tag="KRQ43_001104"
     CDS             52339..52953
                     /locus_tag="KRQ43_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2741474.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVSDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            53044..54600
                     /locus_tag="KRQ43_001105"
     CDS             53044..54600
                     /locus_tag="KRQ43_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HBH2741475.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNRLDSESK
                     RNFKKLCKENIKKSMFVVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDKKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKETKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEELNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            54590..55852
                     /locus_tag="KRQ43_001106"
     CDS             54590..55852
                     /locus_tag="KRQ43_001106"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBH2741476.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            55926..57713
                     /gene="aspS"
                     /locus_tag="KRQ43_001107"
     CDS             55926..57713
                     /gene="aspS"
                     /locus_tag="KRQ43_001107"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBH2741477.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTKMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDIQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            58172..59404
                     /locus_tag="KRQ43_001108"
     CDS             58172..59404
                     /locus_tag="KRQ43_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH2741478.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            59418..60224
                     /locus_tag="KRQ43_001109"
     CDS             59418..60224
                     /locus_tag="KRQ43_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HBH2741479.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKHGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(60336..61205)
                     /locus_tag="KRQ43_001110"
     CDS             complement(60336..61205)
                     /locus_tag="KRQ43_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH2741480.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            61576..63003
                     /locus_tag="KRQ43_001111"
     CDS             61576..63003
                     /locus_tag="KRQ43_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HBH2741481.1"
                     /translation="MKLTKSISSMLCLALVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFLNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEIFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(63079..63348)
                     /locus_tag="KRQ43_001112"
     CDS             complement(63079..63348)
                     /locus_tag="KRQ43_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741482.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGISINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(63351..64793)
                     /gene="nhaC"
                     /locus_tag="KRQ43_001113"
     CDS             complement(63351..64793)
                     /gene="nhaC"
                     /locus_tag="KRQ43_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH2741483.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAATKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDILNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(64818..65984)
                     /locus_tag="KRQ43_001114"
     CDS             complement(64818..65984)
                     /locus_tag="KRQ43_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH2741484.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESVLVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIK"
     gene            complement(66209..68329)
                     /locus_tag="KRQ43_001115"
     CDS             complement(66209..68329)
                     /locus_tag="KRQ43_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2741485.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVVDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHIARKILSINANEMIDSFVGDCIKDINFQNILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERAADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLGK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            68562..68963
                     /locus_tag="KRQ43_001116"
     CDS             68562..68963
                     /locus_tag="KRQ43_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741486.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            69006..69299
                     /locus_tag="KRQ43_001117"
     CDS             69006..69299
                     /locus_tag="KRQ43_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBH2741487.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            69314..69754
                     /locus_tag="KRQ43_001118"
     CDS             69314..69754
                     /locus_tag="KRQ43_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HBH2741488.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(69846..70319)
                     /locus_tag="KRQ43_001119"
     CDS             complement(69846..70319)
                     /locus_tag="KRQ43_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH2741489.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(70319..71107)
                     /locus_tag="KRQ43_001120"
     CDS             complement(70319..71107)
                     /locus_tag="KRQ43_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH2741490.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            71435..72679
                     /locus_tag="KRQ43_001121"
     CDS             71435..72679
                     /locus_tag="KRQ43_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH2741491.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGIHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLINKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            73002..74099
                     /locus_tag="KRQ43_001122"
     CDS             73002..74099
                     /locus_tag="KRQ43_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH2741492.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEITIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            74090..74788
                     /locus_tag="KRQ43_001123"
     CDS             74090..74788
                     /locus_tag="KRQ43_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH2741493.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            74791..75855
                     /locus_tag="KRQ43_001124"
     CDS             74791..75855
                     /locus_tag="KRQ43_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH2741494.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            76038..76742
                     /locus_tag="KRQ43_001125"
     CDS             76038..76742
                     /locus_tag="KRQ43_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2741495.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            76735..78057
                     /locus_tag="KRQ43_001126"
     CDS             76735..78057
                     /locus_tag="KRQ43_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2741496.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            78244..79617
                     /locus_tag="KRQ43_001127"
     CDS             78244..79617
                     /locus_tag="KRQ43_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741497.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIVMYIFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(79990..80928)
                     /gene="pdaA"
                     /locus_tag="KRQ43_001128"
     CDS             complement(79990..80928)
                     /gene="pdaA"
                     /locus_tag="KRQ43_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH2741498.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDGGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        31836 a         8877 c        13990 g        26464 t
ORIGIN      
        1 aatttcaaat aatgttgtag attctaaact tacgaatagt aggattaaat caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcgg attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaaactaaa
      241 aaataataaa tccacactga gtataatact tagtatattc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attacctagg aaatcctgat ttaaattctg tgagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agtttagtat atttactact
      421 aaaaaaatta aatgttggaa gtactgctac aataattact tttctatgta tagctacatt
      481 tataatagtt gggtactaca tattagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa gggacatttg tacaagccag aatttgaacc
      601 agatggtttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaaa acataggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatag gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 attatggtct agctcatttg tacttttaat ggctggcagt tatggtatgt tactgtcaat
      841 attttatttt atatgtgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tggaagtagc cctattttta catatatgtg ccttgagata ttgagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttatatttt ctttattgta
     1081 tgtcctattc tgggttatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagat gataaagtct ttgatttgtt caaatatacg gaaactatca
     1201 aatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagattta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgttgtctg
     1441 tagcaatggt ggcaccaaac gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aataacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaagcataa
     1741 aaataaatgg taaagatgaa cagaaagttt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacacaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcgccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacaaggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgatgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 aattaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt atctcaaatt aaatctgctg taaatgtaaa tgtaactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agactctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaaattata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag actttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gactcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aagacttatg
     2701 tttctgcata ccatagcaca aacttatcag aaaaaacagc aggaacagta tatcaaattg
     2761 gtgatgggat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcgggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gtcatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gacaaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 acactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggagctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaataac aattatccag
     3301 caatacttgt tgaatgtgca tttattgaca ataagagcga tatggataag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaataaaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacgg ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattaa gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggat atgggcttaa
     4081 taggccctag accagagaga ccgaacttta ctgttcaatt caatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt ttaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagca caatagaggt atttgcagat
     4501 gcaaatccca aaagagaatt gatagaaggg agtataccag agatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc agtatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 ataaaagtag aaagaataag aggaaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaatgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gtaagaatct taaaaaaata
     5041 tatgcattag gtgattcaaa agaatttatt gcagagattg attctaactt gaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctaaattag actttggtag cagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaagagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttaatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gtttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattgggct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctaagtgg aagtaagata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaacgt atggatacta ccagcaggag cactattggc tatggcgagt
     6181 caactattat ttcaactgcc atttgcattt aagaagtcct acaagtataa gccatatata
     6241 aacttaaagg atgagtctat aaaagaatta gtaaacctag tattgcctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gacagattat tggcaactac tttgggtgat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aagctagcaa aaatgtctgg taaagatgat
     6481 aaagaaggat ttataagtac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttaggatatt atttcaaagg
     6601 ggtaaatttg atgcgttatc aacagatctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacgc caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattagg tcatgcaggt attgctatat caactagtac atccaatata
     6841 attacagtta tattgttatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggactt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagaagat aattaccttg aaattttaaa ttagagtcag aaaggatgaa aatatggatt
     7201 ataagaataa ttatgagatg tggttaaatt ctccttattt tgatgagcaa acaaaaaatg
     7261 agctattaag cataaaagat gatgaaaaag aaatacaaga tagattctat aagaatttag
     7321 agtttggaac aggtggttta agaggtataa taggagcggg aactaataga atcaatattt
     7381 atactgttag acgtgcgaca ctgggcgttt taaattatat catgaagact caaggagaag
     7441 aaggtaaaca aaagggaata gttatagcac atgatagtag atacatgtct agggagtttt
     7501 gtatagaagt agcaaagact ttaagtgctt atggtgtaaa ggcttatatt tttgaagaat
     7561 taaagcctac accagaactt tcttttgctg ttagatattt aaagtgtgct atgggaatag
     7621 taataacagc aagtcataat cctaaagaat acaatggata taaagtatat gactcagatg
     7681 gtggtcaaat ctgtatagat atggcaaatg atataatagc agaagttaat aagattgatg
     7741 attacagcac tattaaaagt atagattttg aagaagcttt atctaaaaat ttaataacta
     7801 tattagataa tgaagtagat gatgagttta taaaagctgt taagaagcaa gttttaagac
     7861 aaaatataat agatgaatac gggaaaaaat taaaaataat atatacacct attcatggta
     7921 caggaaataa accagtaaga aaagtcttaa atgaatgtgg ttttgaaaat gtaatggtag
     7981 ttaaggagca agaattacca gattctaatt tttcaacagt aaagtatcct aatcctgaag
     8041 aaaagtcagt gtttaatata gctattgaaa tggcaaagaa taatgacact gatttgataa
     8101 taggaacaga ccctgattgt gatagagtag gtatcgttgt aaaagattca agtggtgaat
     8161 atgtagtctt aaatggaaat caagtcggtt cacttttagt tagatatata ttagagagtt
     8221 tagttgaaga aaataaactt cctaaaaaca atcctacaat aataaaaact atagttacat
     8281 cagaactagg tgcaaaaata gcaaaggctt ataatgtaga ttgtttaaat actttaacag
     8341 gatttaaatt tataggagaa aaaataaaag cgtttgaaga aagcaatgat agaagtttta
     8401 taatgggata tgaggaaagc tatggttact taattggaac tcatgctaga gataaagatg
     8461 gtgttgtatc ttcacttatg atatgtgaaa tggcagcata ctattcttca aaaggtatga
     8521 acttgtatga agctttgata gatacatata ataaatttgg atactacaaa gaggacttaa
     8581 agtcagtaac tttaaaaggt atagatggaa taaaaaaaat aaaagagatg atgctttact
     8641 ttagaagtgt taaaatagat aatgtggctg atgtaaaagt agataaaatt ttagactata
     8701 aagatggtgt tgatgattta cctaagtcag atgtacttaa atttttactt gaagatggct
     8761 cttggatagc tataagacct tcaggtacag aacctaaaat taaattttac tttggagcaa
     8821 attcagacaa tcaagaagat gtagaattta agttgaacaa tttaatatct tatatattaa
     8881 atgtagtgga ttctatataa aaagctaagg ggagataaat aatgaaagta tacaatgtca
     8941 taatggctgg aggaggagga actcgtttct ggccacttag tagacaagaa gtacctaaac
     9001 agcttataaa tttaagtgga gaagatgctt taataaacga aactataaac agaatagatt
     9061 ctctagcaaa aaaagatgat ttatttatag taaccaatga gaagcaattg gaagctttaa
     9121 aggatatagt aaaagataaa tgtttggata gtaatatatt gccagagcca tgtgccagaa
     9181 atacagcagc agctataggc tttgcagcat ttaacataat gaaaaaatat ggtgatggtg
     9241 ttatgtgtgt atatccagct gaccattata taaaagatga aaaagaattt aaatctattt
     9301 tggaaaaagc tatctatata gcagaaaata atgataaact agtaactatt gggataactc
     9361 ctacatttcc atcaacagga tatggataca taaattttaa tagagaaaat acgatagaag
     9421 atgttgcata tgaggtagtg gagtttgtag aaaaaccaaa ctatgaaatt gctaaagaat
     9481 atgtaaactc taaaaagtat gtatggaata gtggaatgtt cgtatggaag gtatctaaaa
     9541 tattagaaga ttttaagaga tacttgccaa aagtatatga aaaattagaa tatataagta
     9601 aatacttagg aacaaaagaa gaaatggaaa aaataaaaga aatataccca actatacaat
     9661 caatctctat agattatggt attatggaaa gaagtaatga tgttatagta gttcctggtg
     9721 attttggatg gaatgatgtt ggttcttggg attctctagg tgcaatatat ccaactgatg
     9781 atgaaggtaa catcaaaaga ggtgaaaata ttactataga tactaaaaat tcaattatat
     9841 attcagatga caaattaata tcaacaatag gtattagtga tttgatagta gtatctacga
     9901 atgatgcagt tatggtttgt agaaaagata aagctcaaga tgtcaaaaaa atagtagaac
     9961 agttaaaaga agaagataga caagaatata tgtaggaggt gttcatttga ttcctaaaaa
    10021 aatacattat gtatggtttg gtggtccaaa aggaaatata gaaaatatat gtataaattc
    10081 ttggaaagaa aagcttccag aatatgagat agtagagtgg aatgaaaaaa actttgatat
    10141 agagaaagaa ataaaaggaa ataagttttt ggaagaatgt tataaaagaa aactttgggc
    10201 attcatatct gattatacaa gaataaaagt actctatgaa caaggtggag tttatatgga
    10261 tacagatatg caaatattaa aggatataac tcctctttta gaaaataata ggctaatctg
    10321 tgggtatgaa gatgatagag agtatataaa tggtgctata ataggtgtag aaaaaggaca
    10381 tcctttttta aaagacttat tggagtatta tgaaaaagaa gtacttactt cttcattgtt
    10441 tacaatacca aaaataatga ctcatcttat ggaaaagaat tataagaaga ttgacccaaa
    10501 taattatgaa gaaggaatac gtgtttacga caaagaatat ttttatcctt ttggatttaa
    10561 agaagacttt acaccagaat gtataacaga aaacactttt gggatacatt ggtggggaaa
    10621 aagttgggct aaaaagagaa attatttctt agaaagcaaa cacttaacag gtgtaaataa
    10681 gatatggaag tgttgtaaaa tatttgcaag taatacttta cgaagctaaa agggagaaag
    10741 taaaatgaag actttaaatg atgatagaaa tattatgatt agaaaatatc tttatatatt
    10801 tgttttgttt atcatattac ttagaaagta tatgatatca tttattgacc caaatataga
    10861 tatagggatg attaaatcag cgttatttta ttcttcaata ggaatactaa tgctactttt
    10921 tttatttgat aagagaaaaa gtataacaga aatggtacta gttggagttt gtgtcttact
    10981 ttatttatta aatagggaag gagctatatt attaatcgtt ttattagctg tatcagctaa
    11041 gcaaatagat gataaattta tagttaaaaa ttatttaata atatcggcat gttttttaat
    11101 ggtagctata ttattattta atttatttcc ttcattaata tttaatcagg aagtccacta
    11161 tagatatata gaaaaaatag atatgcttgt tacaagaatg gattttggac ttggtaatcc
    11221 aaatagtgta ttttatcata tggttactat atatgcagca tatatattct taagatataa
    11281 agattataat aaatgggata gaataatttt atttggttct gcattttttg tttatcaaac
    11341 cacatatagt agaactggat ttttcactat attagcagga ttaatatttg tagaaataat
    11401 aagatggata gatataaaaa aaataaaagg actgccaatg ctcctaaaga cattaccaat
    11461 aatacttact ctatttagtg taattattgg tacaatattt gataaaagca ctttattaaa
    11521 tagattatta gcaagtagac ctaagttctg gcatgtatac ttggctgaaa aggggaattt
    11581 tctaaaacct tttggaaatt catatagtcc tgctataaaa gcaactaatc cattagatag
    11641 ttcttatgta tatataatta gtgtactagg agtagttgct tgtatattat ttatgtattt
    11701 gatgtataaa ggaatagaaa gctttataga aaaagataaa aaagcatatt tagtagcttt
    11761 atttatattt ttactatact cttttgcaga aaatttatta ttagaagctt catttagttt
    11821 tgcagtagta ttactaataa aagaagtgat attaaatgat aaaagggaaa tagatttgtg
    11881 gaagatgaaa agtaggaggt agtaatgtta atatcattaa taatgccaac attaaataga
    11941 tatgatgata tatacttact tatggatagc ttagaaaatc aaacttacaa aaactttgaa
    12001 cttatagtag tagaccaaaa tgataatagc aaagttaaag aaatagttga taaatacatt
    12061 gataagttag atataaagta tataaaaagc tctaaaaaag gattgagtta taacagaaat
    12121 gtaggcatag ataatgctgt agggcaaatt ataggtttcc ctgatgatga ttgtgtctac
    12181 gaaaatgata cattagaaaa agttataaat ttctttaata aaaatgaaga ttataaaata
    12241 tacagttgca aaactatgga ttcaaataaa gttgatgcat ttaagaaaat gtatgatgga
    12301 acttgtgata tcacaagttc caacgttttg gatactataa catccataac tttttttatt
    12361 gattttgaag gtaaagatta tacaagattt gatgaaaaat tgggtgttgg tggagagttt
    12421 ggtgctggtg aagagataga ttatgtttta aacttattga gtttaggttt taaaggaaaa
    12481 tactttggaa atgatataat ttaccatcct gcaaaaaaac attctaaatc taaagaaaag
    12541 tatcaaaaag attataatta tggaagaggc tttggagcgc tttgcaaaaa ggaaatagtc
    12601 tatagaaaaa attatacgtt tgcaaaagtt atggtatcaa aacttgtaag aaatataggg
    12661 ggtcttatat tgagttccaa tagagattat catagtgcca ctataaaagg aagaattaat
    12721 ggatttagac agtacaagtt ataatgagga tggtgtttat ggacaaggtt aaatttttaa
    12781 taaatatgct tttggctttt tttatatatc catttaataa gcataagttt aatggtagag
    12841 atatctggct tataggtgga cattcagggg atatatacaa tgataattca aagttttttt
    12901 atgagtatat gctaaaagaa cataatgatg tagaaactta ttgggtagta aataaagaca
    12961 gtaaagtatt tgataaaatt ccaggcaaaa aattaataag aggaagtgta gaaaactatc
    13021 tgtattatta caattcaaaa gctatagtat tttcacatgc accatcagca gatatagcac
    13081 catacaattt tgctgtacct gttcttaatt attttcataa aaaaacgata aaagtgtttt
    13141 taaatcatgg gactataagc tttaaaaaaa gaaaacctat gaacaaaaag ttcaaaaata
    13201 ttatagataa cctatataaa agctataata tagttacagc aagttctgaa tttgaaagaa
    13261 atgttatggt aaatgattgg ggaatgttag atgactcagt ttatataatt gggaatgcaa
    13321 gatatgacaa tttaccaaca aatgaagttg cacaaactcg agatatatta tatactccta
    13381 catggagaga ttggataaaa tttagttcag gaaaatttac ggatacagat tattttaaaa
    13441 atataatgaa ttttttaaat gatgacaaat taaataaaat attagatgag aaagatataa
    13501 atgtaaaaat ttatatgcat catcttatgc atgagtttat agatgatata aaagaaaata
    13561 taacaggaaa acgaattgtg tttttagata aaggggtaac tctagcaaat gaaatcagaa
    13621 aatcagctgc aaatataact gattattcaa gtgtagccat agactttttg tatatgaata
    13681 gacctatctt gttttaccaa ttcgatttgg atgaatatat ggaaaaagtt gattcatata
    13741 tagatttaaa aagtgaaatg tttgggtctt tggcttataa taatgatgaa gccgtgaata
    13801 aacttattga tattattgaa aataattttg aggttatgga taaccaaaaa aatgaaagaa
    13861 ataagttttt cagatataat gataataaga actgcaagag gatatatgat tgtgtattaa
    13921 gtaaaattaa ataaatattt tataaatgat gaggaaggta atatgaagaa gaatttagta
    13981 tctataatta ctcccatgta taattctgaa aaatttattg aagcaaccat aaaatcagta
    14041 ttaaaccaaa cttatcaaga atgggaaatg ttaattattg atgattgctc aacagataat
    14101 agtcctaata tagtcaaatc ttatatgcaa caggatagta gaataaaatg tataaagact
    14161 gagactaata agggtgtctc taatgctaga aatttagcac taagtaaggc aacaggacaa
    14221 tttatagctt ttttagatag tgatgaccaa tggaatagca gtaagttaga aaaacaagta
    14281 aattttatgt tagaaaatga ctatgtaatt tcatttactt catatgaact gatggatgaa
    14341 aatgataaaa aattaaacaa agtaataaaa gttccaccta atgtagatta taaaagatta
    14401 ttaaaaggaa atatcttagg atgtcttact gttgtgattg ataagtctaa attggatttt
    14461 gaaataagaa tgagtggtgt aagacatgaa gactatgttt tatggttatc gatattgaaa
    14521 aaagggcata ttgctcatgg aataaatgaa gttctagcat tatatagaaa atctagcaat
    14581 tccctaagtg gtaataaaat aaaagctgct atgtggactt ggaatatata tagaaatata
    14641 gaaaaaatac ctttatacaa agctatatac tactttatta attatggaat aaacggaatc
    14701 aaaaaaagtt agacagagag gaagatttaa ttaatgtata aatataaatt tactgtattt
    14761 actccgacgt ataacagagc tcatttactt gaaaatttgt acaatgattt aaaagctcaa
    14821 acttatgatt tcaatgattt tgaatggttg attgttgatg atggaagtag cgacagtact
    14881 aaagagttag ttgaaaaatt tatatcagaa aataaattaa atataagata tatatacaaa
    14941 gaaaatggag gaaaacatac tgcaataaat ctaggtgtaa aaaatgcaga tggagagcta
    15001 tttttcattg tagatagtga tgatggttta attaaagatt ctcttgaaat tgctaatgat
    15061 gagtgggatt ctttagagaa taaagaagga tttagtggag ttgttggact ttgtgtatat
    15121 ccaagtggag atttgatagg gacagaaatg cctgaagata agaaaatatg tcactttgca
    15181 gacctatatt ttaagtatgg cgttaaggga gataaaagca tagtatttgt aactgatgag
    15241 cttataaaat ttccttttcc agaaagaaaa gaagtgagat ttttaccaga aagtgtagta
    15301 tggaatgaaa tgtctaaata ctataaagtt atatgtgtaa ataaacctat gataataaga
    15361 gattatttgg atgatggttt gactaagaat atattaagta aaaatgcatt aagaggtaga
    15421 gcattagagt ttttatattt aataaatcaa aatacatatc cattaagtag atatccatat
    15481 atgtggataa aaaattacat aaatttagcc agatactcat tgttgtctga tagtcattat
    15541 tttggtgaat taagaaaagt atctgataaa ttgttgtatt tagcattatt cccattagga
    15601 tattacaaat atattggaca aagaaaatta gtatctaagt aaacttgttg gtatagtact
    15661 gctagttgct atataaggag agtaaaaata tgaatgagcc tttagtatcg ataattactc
    15721 ctgtttataa ttcagaagag tttttatcag agacgataaa gtcaatccaa aatcaaactt
    15781 ataaaaattg gcagctttta ttagtggatg attgttctaa ggacaattca agtgaaatta
    15841 taaaaagttt tcgaaaagaa gatgctagaa taaaatatat aaagcttgaa aaaaattctg
    15901 gagctgcagt atctagaaat gttggtatta agaatgcgga aggtcgattt attgcatttg
    15961 tagatagtga tgatttatgg gatagtagaa aattagagat tcagatagaa tatatgttaa
    16021 aagaaaatgt aggtttttct tttacatctt atagatatat gagacaagat gggtcaaaaa
    16081 cgaataaggt tgcaagagct cctaagaaaa ttgactatga aggattactt agaaatacta
    16141 taataggatg ttctacagtg gtcattgata aggagattgt aggagagttc agcatgcctt
    16201 tggtaagaag aggacaagat actgcgacct ggttacagtt acttaaaaag gaaaaatatg
    16261 catatgggat tcaggaggat ttagtgaatt acagattagt tggaaattct atatcaagta
    16321 acaagataaa agcattaaaa cgaacttgga atacttatag aaatgttgaa aatttaagtt
    16381 taccaaaaag tctatatgta ttttgtttct atgtttttaa tgccattaaa aaaagagtat
    16441 aagttttata tacttggagg taaaaaaatg aaaatagcta tagctgggac gggatatgta
    16501 ggtttggtta caggtgtttg tctagcagag gtaggcaatg aaaatgtagt ctgtgttgat
    16561 gtagatgaac aaaaagttaa atcaatgaaa cttggaatag cacctatata tgaagaaggc
    16621 ctagaagaac ttatggttaa aaattacaac agaggaagaa tagattacac tacagactat
    16681 aaaaaagctt atgaagatgt agatgtaata ttaatagctg taggtacacc tgagagaagt
    16741 gatggctcag ccaacctaga ttatataaag gcagttgcaa agcaaatagc tgaaactgtg
    16801 acaaaagata ctctagtagt aataaaatct acagttccaa ttggtacaaa tgaagagata
    16861 gaagattata taaatagaaa cctaaaaaat aatgtaaaag tagagcttgc atctaatcca
    16921 gagtttttat cacaaggaac agcagtaaaa gatactctat atgcttcaag aatcgttata
    16981 ggtgtagaaa gtgaatgggc tagagaaata ttagaagaaa tctataagcc ttttaatcaa
    17041 cctataatag ttacaaatag aaatagtgct gagatgataa aatacgcatc aaataacttc
    17101 ttagctctta aaatatcatt tatgaatgat attgcaaatc tttgtgaaat agcaggagct
    17161 aacatagaag atgtagcttt aggaatgagt tatgatgata gaataggaag taagttttta
    17221 aaggcgggaa tagggtatgg cggttcttgc tttccaaaag acacaaaagc tcttcactgg
    17281 ttatctgaac ataatggtta tgaattaaaa acagtaaaag ctgcaataga agttaatgaa
    17341 agtcaaaaac ttaaattagt tagaaaggca tctaagttag tagagagctt tcaagatatg
    17401 aaagttgctg ttttaggttt gacttttaaa ccagacactg atgatataag agaagcacca
    17461 tctataccaa atataaaata tttgcttgaa agaggggcaa gagttactgt atacgaccca
    17521 attggtgtaa ataatactaa gaaaatattt ggtgactcta tactttatgc tgattctgta
    17581 gatgatgcga tagaagatgc agagatatgt tttataatga cagaatggaa agatgtatta
    17641 aattatgata tacataagta taaggaaaag atgaaaaatc ctttagtcct tgatggaaga
    17701 aattgttata aaattaaaga tatggaagag ttaggaattg agtattattc gataggaagg
    17761 taaatattat gaagactgtt tgttatttag ctgatgggtc aaatcctcat actttaaaat
    17821 ggtgtagttt ttttaaaaat aaaggatatg acattcatgt aatctcttta aatggaggtc
    17881 acatggaagg aataaaaatt tataattttg gttctaatgt agaagaatta aaaaatgaaa
    17941 atatttctaa aaaaacggga tacttaggtt caataaagca gataaagaag ctagtaaatg
    18001 aaataaagcc agatatattg catgcacagt atgcaagtag ttatggattt ataggaagtc
    18061 tacttgggta tcatccatat attatttctg tttggggtac tgatatttat gatttcccta
    18121 ataatggttt tatacaaaaa caaattataa aacataactt tagaaaagca gactatatct
    18181 tttcaaatag tagagatatg gctaaagagg ctaataaata tacagctaaa catgtagatg
    18241 taaccttttt tggagtagat atggataggt ttaagcctat ggaagtagaa aaagaagacg
    18301 cttttgtaat aggaattata aagagtttag aaaaaaaata tggaatagaa tatttaatac
    18361 aagcatttaa gatgcttaaa gatgaatata aagataagaa aataattctt aaaataggtg
    18421 gctctggaag tcagatggac aacctaataa atttagctaa agaattgggt atagaaaatg
    18481 atgttcagtt tttaggaaga atatctccag aaaatgtaag caagactttt aattcttttg
    18541 atgtaactgt atttccttct ttaagagagg gatttggagt ggcagctata gaatcagaag
    18601 catgtgaagt acctgttata gttacaaatg taggaggaca tccagaatct gtatgggaaa
    18661 atgaaactgg cttaattgta gaaccaaaac aaccagaaga aataaaaaat gctataataa
    18721 aactaatgga aaatgatgaa cttagactta atatgggtaa gaaagggcgt caatttgtta
    18781 gagaaaatta tgaggttaat ttaaacttta atgatataga aaaaatttat gattctatat
    18841 ttgataaata taaaaaataa aatgaaaaaa tacagcaaaa gatagatgtt gttggctatg
    18901 cttaggtgcg tagcttttgc tgtttaaagg agggcttcta gttatgcgag aaagtataga
    18961 tttagagaaa gaaagctttt ttaataggct ttttaaaaaa tataaattta gacatttaac
    19021 actattaatt ctagatattt gtagcgtact agtagcgttt cgaatgtctt taagcttgac
    19081 aggtaattta aatgcattta ccactaatga tataataatt tcagtgtgta tatatatagt
    19141 acttcatata gtatcattta gattgtttaa gtgctacaac acattatgga gatatgcagg
    19201 agaagaagaa attatatcta tttttgtggc aactttagct tatttaattc cgatttatat
    19261 aataaataaa ttattagggt ttgattatcc tataatgttt tatgtattaa atacaatatt
    19321 tattataatg tttacaagtg gcgcaagaat agcttataga gctataagaa tagtcatgaa
    19381 caagacatat tctagaggaa aggtttcaaa tatccttata attggtgcag gagatgcagg
    19441 agaaatggtt atacaggaac taaaaagaaa ttcagaactt aaaaaagtag cagtggctat
    19501 aattgatgat gataaagata aaattggaag aataatccat aatgtgaaaa ttgtaggaac
    19561 aacttcggat ataaaagctg tggtagaaaa gtacaatgta gatgagataa tcttttcaat
    19621 agcaaacata gagaaacgta gaaaaaaaga gattattgat atatgtaaaa acactaactg
    19681 taaaataaag acaataccag gaatttacga aattatagat ggaaaagttg atataaaaca
    19741 gattagagaa gtagagatag aagacttgtt gggtagagag cctataaaaa caaatttaag
    19801 agagataagt aattacattg agggaaaagt aatcctaata actggaggag gaggctcaat
    19861 tggttcagag ctttgcagac agattgcagg atttaatcct aaagagctta ttatagttga
    19921 taattatgaa aataatgctt actcaataca acaagaatta cttagaaaat ataaaaataa
    19981 attagattta aagacagtaa tagcatcaat aagagaagaa aaaagaatgg atgaaatatt
    20041 taataaatat aaaccagaag tggtatttca tgcagcagca cataaacatg ttcctcttat
    20101 ggaatcgagc cctggcgaag ctataaagaa taatatattt ggaactttaa acatagctgg
    20161 cttgtcttca aaatatagag ctaagaaatt tgtccttata tctacagata aggctgtaaa
    20221 ccctactaac ataatgggag ctactaaaag agctgctgaa atgattatac agactatgaa
    20281 tgctgaaagc cagactgaat ttgttgctgt tagatttgga aatgtgcttg gtagtaatgg
    20341 tagtgtaatt ccacttttta agaagcaaat tgaagatggc ggaccagtga cagttactca
    20401 tccagatatc attagatatt ttatgacaat accagaagca gtaggcttag ttatacaagc
    20461 tggggctatg gctaaaggtg gagaaatatt tgtgcttgat atgggagaac ctgtaagaat
    20521 attggattta gcaaaaaact taattaaatt cagtggattt gagccagatg ttgatataaa
    20581 aattgaattt tctggtctta gaccaggaga aaagttgtat gaagaactac ttatgtcaga
    20641 agaaggtctg ttggatacag agcataaaaa gatttttatt ggtagaccaa tagatgttga
    20701 tagagaaaaa ataacaaaat acttaaaact tttaagagaa attactaaca atgaagaggt
    20761 tgaaaaaata gatggtatta tgagggaatt agtgccaact tatattaaac cagaagatgc
    20821 taatatcaaa gaaattgcaa caactagaga aaagtagaat atatttctaa tttgtaacca
    20881 gggggagcaa aaagaaacaa atatatacta aaaagaaaca aaagattaca aaaagattac
    20941 aaaaagatta caaaaaaggt tgcaatttat tttgatgtaa gatagaatgt taattaggaa
    21001 ttggaaacga aggaacaaaa tgttaaattt tcgaaaggat taggtatttg agattatgat
    21061 gaatattaaa aataaaaaac atatattgaa aaaatttata gctatggtgt taatagcagg
    21121 agttgtcaca gtagaagcag gagcaataac ggctagtgca gcagagccaa ctaattcacc
    21181 tatgagtgca acagtagacc agtgtgattt tttaaatgta agaagtggag ctagtgcaaa
    21241 tgatgcagta gtaggaaaga taaacacagg agacaaagtt gaagttttag aattacattc
    21301 aaatggatgg attaaaataa aaagtgttga caatgttaca ggatgggtaa atggagatta
    21361 tttaactatt caaggtggaa atgtagatgc aaaggtacaa aatgttttaa acttagcatt
    21421 taagcaacaa ggtaagccat atagatgggg agcaactgga ccaaatgctt ttgattgttc
    21481 tgggttcact tcttatgtct ataaaaatgg agcaggggtt aatttaccaa gagtatcaag
    21541 atcacaagca acagtaggaa agaaagtatc aagagcagaa ttaaaaccag gagatttagt
    21601 tttctttggt tcaggtggtt caataaatca tgttggattg tatgtaggag attctaaatt
    21661 catacattca ccacaaacag gagatgtagt aaaagttact agcatggctc caggaactaa
    21721 ttatgcaaga agacttataa ctgctacacg tgttttacaa taataataga tattgattta
    21781 cataggattg aatattaaca ttaaatatat aattacattt aatgttttac atagagattt
    21841 aagagtttag taatattaaa atagtgatga acgttataaa aacagcaaag aagataaatt
    21901 tctttgctgt tttttttata ataaattatt tcatattata atcaaatatc aaatataaat
    21961 tttaactata ttattcaata tttgacagat aatatgaatt ttagatatac ttaataagaa
    22021 gtatattgta gaaaaaataa atttaaaaaa ttaaggggga tgaaatgaaa aaaataagta
    22081 tattagtatt atcattgata atgacactta ctatgtgtag tgtaagttca tttgccgatt
    22141 catcaaatga taaggaaatg agagctgctt ggatatctac agtttataat ttagactggc
    22201 ctaagactaa gaataatgaa gccaagcaaa aaaaggaata cacagattta ttggacaaac
    22261 taaaaagtgt aggaataaat acagcagtgg ttcaagtaag accaaaatca gatgctttat
    22321 ataaatcaaa tataaaccca tggtctgaat atcttaccgg tacacaaggt aaagaccctg
    22381 gatatgaccc attaccattt ttaatagaag aagcacataa aagaggaatg gaatttcatg
    22441 catggtttaa tccatataga ataactatgg cagatgagag catagataaa ttgccagcaa
    22501 accatccagc aaagaaaaat ccaagctggg tagttaaaca tggaaataag tattactacg
    22561 acccaggttt accagaagtt agaaagtaca tagtggatag tatagcagaa gtagttcaaa
    22621 attacgatat agatggagtt cattttgatg attacttcta tccaggagta agtttcaatg
    22681 atactgcaac ataccaaaaa tatggaaaag gacaaaataa ggataattgg agaagagaaa
    22741 atgtaaatac tctacttaga gatgtaaaag cgtctataaa gagtataaag cctaatgttg
    22801 tatttggtgt aagcccagca ggtatatgga gaaataagag tagtgaccca acaggttcag
    22861 atacatcagg taatgaaagt tatgtaggta catatgcaga tacaagagca tggataaaac
    22921 aaggattgat tgactatgta gttccacaac tttactggcc aattggtctt aaagcagcag
    22981 attattctaa attagtggca tggtgggcta atgaagtaaa aggaacaaat gtagacttat
    23041 acataggaca aggtatatat aagcaaggtc aatctagtta tggtggacaa aatatagcaa
    23101 aagaaatagt acaacaagta acattaaata gaaagtatag tgaaataaaa ggtagtatgt
    23161 atttctcagc taaagatata gcaaatagta cttctataca aaaggattta aagagtttat
    23221 attctagtag tgaagaacca gttactccac catctaatgt taaagtggag aaattaagag
    23281 gcgacgaaag atatgacaca gcagtagcaa taagtaaaaa aggttgggct acaaattcag
    23341 atacagtagt attagtaaat gggtactcta tagttgatgg cataacatca acaccacttg
    23401 ctacatcaaa tgatgctcct atactattgg taaataagga taatatacct acatccacta
    23461 agaatgagtt aaaaagactt aatccaagta aagttatttt aattggagga aataactcta
    23521 ttggagataa agttgagagt gagataaaag atacattgtc aaatgtatca ataaatagag
    23581 ttggtggttc agatagatat agtacatctt taatgatagc aaaagaatta gtaaaaacta
    23641 atccagtaga aaaactatat ataacaagtg gtacaggtga agcagattct ctttctatag
    23701 cttcaaaagc aggagaagaa aagcaaccaa tagtactagt atcaaaagat aatgtaagtg
    23761 atgaagttta caattggata tcagatttaa aagtaaaaga tgcttatttt ataggtggta
    23821 atctaagtat atctgattca gtaataaata agctggataa ggtcattaca aatgatgtat
    23881 ctaaaaatag aatagctgga gaaaatagag aagaaacaaa tggaaaagta atacaaaaat
    23941 tctatccaaa tgctgaatat tcatcaatgt ttgtaagtaa aagtaatcaa ttggtagatg
    24001 cattaacatc aggtccttta gcagctaaat taaaatcacc agtagttatg cttggaaata
    24061 gtgtaacatc tgctcagaaa actgctttag agcctaagaa aactgctcta gtatacgaag
    24121 ctggagatgg tataaatcaa aacacattaa acactttctt aaacttagtt aagtaataaa
    24181 aaagttaatt taaaatacag agtattttat aaatgtagat taaaatgaaa attatcatca
    24241 taaattagaa aataaaaaag aactatatgc attttgtaat caagtgtaca cagcaacttg
    24301 aaaataatta tgcgatatag ttctttttta gtaattaatc ttatactttt taataaactt
    24361 tatgttgaat tttttattgt ttaaactcta tgtcattaaa tataaaatcg tgtaatatgt
    24421 ctaaagtatc tgggtcaaat ctaagaaccc atccagcttt tccatatata ccacctgtac
    24481 tatgaatttc atcatcaata ggaaattcaa attgcttaat atttaagtca cccattttta
    24541 aaacttgagc tcctaaagaa agtattgcat taggcttcat gttagtttta acatatggaa
    24601 gaactgcatc taataaacct ggatatttag taacaggtaa agtttccgtt ttcttgatta
    24661 tagcttgtat aatctgtctc tgtctgccat ctctagcaaa ggctgtatcg ttgtgtctga
    24721 tacgtgcaaa agatagtgcc tgatatccat ttagagtctg ctttccagag tttctaatgt
    24781 attgtatgct acctttatca tcacttttat tccatttata agtttcagga ataaatttat
    24841 ttagttctcg tatttctcct ttttcaacag taacctcaac gccaccaata gcatcaatta
    24901 tatacataaa tgattcgaaa ttaacacaag cataattttg aatatcaata ttaaaattct
    24961 cttcaattgt ttgtattaat aaatcagctt gtccataagc ataagcatga gtaagttttt
    25021 gtttaccatg accagggatg tctacatagc tatcacgagc taatgatgta agtttgatat
    25081 cattgtgttt gttatcaata gtaagtatca tcatagcatc tgaccttgaa gaatcttcat
    25141 ttggtctagc atctgttccc ataagtagta tgttaattat cccatcttca tttttatggt
    25201 cattgttatc caataaatca ctacttatgc tcgagtcatg aatagcagat aatttataat
    25261 aaaaatatcc atagacactt atagggaata ttactaccaa gaaagccagt agtataacaa
    25321 atttctttaa ttttgacaaa agtacccctt ctttcttctt tttcctgtat attttttaat
    25381 agcatacact taattatatt aaagtattga gatatattca atacttgttt cagttacaaa
    25441 aaaaagacaa tgatataatt tataagaaaa tttatcgacc tatatgtata gttaaaagta
    25501 tatataatat attttttaaa agtaatttat attttaaaat aaaaacacac cccataaata
    25561 caaagcaatt tgcatttaag aggtatgtat ttatcatcaa attattggtt tgttttggaa
    25621 tttctaatct tcaaccataa tatctttaaa tatgaaatca tgcattgcat ctagttcata
    25681 ttcctcaaaa ggtattacat agcctgcatt acctattttt ctaccatttt cagtagaaag
    25741 aggaaactcc atagatttca aatttaaatt tcctatactt aaaagttctt ttcctaaaga
    25801 tattatttca ttaggattca tattagtttt tacatacgga agtattgtgt taactagatt
    25861 aggatattta gtgactggta aatccttaac accatttatt aaactctgta taacacttct
    25921 ttgtcttcta tctctttcat ctgtactatc attttttctt atacgagaaa atgcaagtgt
    25981 ctgatatcca tttaattttt gctcaccaga atttcttata tatttaagag aacctttatt
    26041 gtcattttta ttccatttat aagtttcagg aataaattta tttaattctc ttatttcact
    26101 cttatcaaca gtaacagtaa ctccacctaa agcatcaact atatccataa aagagaaaaa
    26161 gtcaactacg gcgtagtttt gtatatcaag ttggaagttt tcttctatag tttctattaa
    26221 taagttagct tgtccatata cgtaggcatg tgttaatttt tgttctccac gtcctggtat
    26281 atcaacataa gtatctctat ttaatgaagt tagcttaaga cttttatttt tattatcaat
    26341 agtaagtatc atcatggcat cagaacgaga aacttcttct cctggtcttg catctgtacc
    26401 taacaataat atgtttgtga tattttcttc gtttttatag tcattactac taagcgcctc
    26461 tgtatttata ctatcatctt gtatagtttt taatttagta aaaacatatc catatatact
    26521 aacaggaaat gctataacta aaagggctag aaatataacg aactttttga gtcctgacaa
    26581 taatatcccc tactttctaa attttttaat tacacatagt taattatatt aaaaatttgt
    26641 tacataagca ataaaaaaca caataaatta gcataagttt gtcataatat aattattttt
    26701 atagtatttt atagaagaaa gtgtgtagtt attattgatt ttattggaat ataattgtat
    26761 gaagacttaa atttttataa actgatgtgt atattgaaaa aaatattttc ctgaatgtag
    26821 ttatagcatc ttatgaaagg tgtaaattgt aatttaaaat ttttagtgta taataagaat
    26881 tgaaaattca aaccgataaa aattaataaa aaataattat aaattaataa tttgggggag
    26941 gaaatgtatg ataaaattaa tagcaacaga tttagatgga actttgttag atgaaaagag
    27001 cgaaataaat ccagagtttt ataaagtatt taaaaaatta agagagagag ggataatgtt
    27061 ttctgctgct agtggcaggc agtatcaaaa tcttataaaa aaatttgaag atataaaaga
    27121 tgatatgatg tttatatcag aaaatggaac actagtagta tataaaggaa aagaaatatt
    27181 atcaaatcct ttaaataaag aattagtaaa tgaaatcata gagacaacaa gaagtataaa
    27241 agggaaaaaa attgtaatga gtgggaaaaa atacgcttat atagaaagca aagatgaagc
    27301 gtttatacaa gaggttagta cttattatgc aaagtttaaa attgtagacg atttgacgaa
    27361 agtagaaggc gatatattga agatagctgt atttgacttc aaaggtgcag aacataataa
    27421 taatatctac tttgaaaagt tttctgatag agctcaagta tgtatttctg gagtggagtg
    27481 gcttgattta actgcaaaag gtgcaaataa agggagtgcc ataaaaaaag tacaaaaaat
    27541 gttagatata aaatatgaag aaactatggt atttggtgac cagttaaatg atgtggaaat
    27601 gatgaaaagt gcctatcata gttatgccat ggaaaatgca aatgaacatt tgaaacaaat
    27661 tgctagattt agagcaaaaa gaaatactga aaatggcgtt gtagataaga taaaagaggt
    27721 cataaaaatt ggatagtcat atgtatagat gaaaaagatt attttgaaga aatcaaaaaa
    27781 atatcaatgt aattttgata aataagttta tttatgcgaa aattacattg atatttaata
    27841 aacatcaata atagatattt atttttttat gatattcagt attttgtttt ctatttgagt
    27901 tgcattttca gcagaaatta aataaacata tctacctgct ttctcaatta tagtattatt
    27961 tgctatttca gaattgattt tttctccatg tccttctcca aaaggtgctt gtatcatatc
    28021 ttttttataa ttttctagag ttttatatat tttatctacc tcgtcagttt ttataacgat
    28081 aatatcttct agagataatt tttcagaaga attaattaca aaaccttgaa ttatgtcttc
    28141 ctctacatca ttaaaatagt taaagtcctt tgcatcaaag atttttgatt cttttataag
    28201 taaatcagaa gattttaatg ctttttttat ttttgatgta gaaacgtttt tgtaatcacc
    28261 acttgaagaa caactaacca ttcctaatga taagattatc gaaaaaaaca atattaaaat
    28321 ttttttcatg ataaacctcc aagtttttta aactctgtct taaattagtt tactacataa
    28381 ttatataaaa ataaatgtat ttaatgttac agttttgatt aataatgtaa tattttgata
    28441 ataataccta ttgagaggtg attagaaatg agaataccaa aacatgtagg aattataccg
    28501 gatggaaata gaaggtgggc aagtcaaaat ggtatgacaa aagataaagg atatgaaagt
    28561 ggaatagacc ctggattaga gtcttataga ttatgtagag atttaggctg tgaagaggtg
    28621 actttttatg gatttacaac tgataataca agacgtccat cagtgcagac aaaagctttt
    28681 acaaaagcat gtattgatgc tgcaaatata ttaatagatg aaggtgctgc tttattagtt
    28741 gtaggaaata caaaatctcc aatgtttcca gaagaattat taccatatac taatagaatt
    28801 aaagccaaag aaggtcaaat aaaagcaaat cttctggtaa attatgggtg gtattgggac
    28861 ttaaataata tatcaggagt agaaaatgta aataaaaata atatacagga ttacatacag
    28921 tcatttgatg tatccagact agatttaata atcagatggg gtggaagaag gagattaagt
    28981 ggtttccttc ctgtacaatc aatttatgca gatttttatg ttatagataa ttattggcca
    29041 gattttaaga gtgacgatat aaaggacgca tttagttggt atgatacaca agatgtcact
    29101 ttaggtggat aattaaaaat attctgattt aaggttgtag agtgttttaa attattgaaa
    29161 aaaaaacttc ttgatggtaa aataacacta ataatatgta aaagtgtaaa aatttatacc
    29221 aagaagggtg aagaaatgtc aaaaggcaat aataacaata attcaagaaa caaatctaaa
    29281 aagaccagtc atctgaatag aaaaaagcga aaattaaata agaaaaagtt agcagtgttg
    29341 atttgcttta cagttttatt tttatttatt gcatttaagg ctactcaagg tgtagtagct
    29401 ttggtaaaaa gtatggataa aagtaataaa actagtcaac aacaaaaagt taactcagaa
    29461 caatttgacc ttggtaatga agaggaaaat aaaaagaaaa aatatactgt atttatagac
    29521 ccaggtcatg gaggcaatga taaaggaact gaaagcaaga ccagtaatag atatgaaaaa
    29581 gacctaaatc tacaaattgc aaaaaaatta gcaaataaat tatctaaaca aaaggatatt
    29641 caagtagtag tatccagaac tgatgataca tatatatcat taaaggatag agctatctta
    29701 gcaaataata gttctgctga tgtgcttgtt tctattcatt taaatgcaga gaaaaatggt
    29761 aatacagcaa caggtataga aacttggtat aggaataaag ctacagatgg ttcaaaagaa
    29821 cttgcacaga cagtacaaag tactatagta tcctatgtta aagttagaga taggggaata
    29881 gttgaaaata actttgaagt acttagagaa tcaaatatgc ctgctatatt aatagagtgt
    29941 ggttttttaa caacaccttc agaggaacaa aaaataataa atgaaaaata tcaagaccaa
    30001 cttgcggaag gaattgttca aggtgtactt tcatacctag attctaaagg gaataagtaa
    30061 gttaacttta ctttaatgtg aggataaatt taaaagttta actgtgtaaa ttgtattaac
    30121 tttatttcgt aatgttggaa acattgtttg aatttagaaa ctatgaaatt agaaattatt
    30181 ttatctatat ctaatttcat agtttttttt gcaaaaaatt tatagttata aaatttaaaa
    30241 aaataaattt agtataatgt aatgtagtta tttatatgtg attttaactt gcattgattt
    30301 gctatcaatt gtgctttata attagtatat ataaagttta actgtaagat aatttaaaaa
    30361 ataggggaat ttatatgaat aaaaatagca tgacaaaaat ttacagttta aataaaataa
    30421 tttttattat aattggaatt ttaggaatag ttttacttac aagacatatt gaggtagata
    30481 ttaaagtttt aattttaatt ttattaactt tgtttagtat aaatgtattt atttcatatc
    30541 ttaaaattaa gttgtatgag gataaaatta atttaggatt gataaataat tcagataagt
    30601 ttataaatat tactaaagat gagaacttcc taaaacatgt tcaaaattat attatcagta
    30661 atgaaaaaga aaactgtgta atggcttgtt ttgatttatg tagactcaaa cttataaatg
    30721 atatatatgg ttatgagcta ggggatgaag tgttaaataa tattttaagt aacttaaaaa
    30781 attattttgg aaaagaagct atttatggaa agttaaaaag tgatgttttt gtattaataa
    30841 taaagcttga aaatagggaa cagaagattc cttatttagt aaatcttatc aagaataaaa
    30901 ttatgatatt aagtcagatt gacagtttta aaatggatat aaatattgag gcttctattg
    30961 gaatttataa atttaacaat aatgaaattg atataaaaaa agctatagat aatgctgata
    31021 tggcaaggct taaatcaaaa ggactaaagc acatagagta tgtagaattt gataatgcta
    31081 tggaagaaga aatacaatca attatgaaaa tagagagaga tttattcttg gctattaaaa
    31141 ataaagagtt tgtaattcac tatcaaccta aagttgattc aagtacaggt aacattatag
    31201 gttcagaggc attgataaga tggttgcacc catcattagg catggttgga ccaaataagt
    31261 ttatacctat agctgaaaaa aatggtctga taaacaatat tggtagatgg ctaattcaag
    31321 aagtttttat taccattaac aagtggattt cagaaggtat aaatgtctta ccagtctcaa
    31381 taaatctttc tagagtagaa ctatataaaa atgatttagt tgattttttt aaactgatgt
    31441 ttaatacata taatattcca aaagaactta tagaattaga aattacagaa acgacagcgc
    31501 taagagatgt aaaatttata agtgaaaggc tttatgagat taaatcttta ggtatgaata
    31561 tatcattaga tgattttgga gtaggtaatt caaattttat caatcttaag gggataccac
    31621 tagatattat aaaaattgat aggtcactta tattggatat agttacaaat acaaaaacaa
    31681 agtttatggt gaaagcaatt attaaccttt cacatgattt aaacgtaact gttatatgtg
    31741 aaggggtaga ggatatgcat caggtcaaag tcttaagtga actgggatgt aatttcatac
    31801 aaggttatgt attttttaaa cctttggatg agatgaatta taaaaaactt cttactgacg
    31861 gaagttatat aaatctgaaa gatactcttt tagataaatg catgacagtt gaggaggagt
    31921 aaggatgatt tcagaagatg tagattattc aataagaatc ataagagcta tatttaataa
    31981 tggagaagat aaaccaatag atgctaaaat gatattaaaa agtgaagata taccaatact
    32041 aacactatac agactgctta gaaagctttg tgcaaacaat attcttactt ttaacaaaga
    32101 agatggcaag acatacatgt taaatgtgtc attggataca ataagtctaa gaactattgt
    32161 agaagtaatt gatggaaaaa tatatataaa taaatgtacg agatatgtat ctaattgcag
    32221 taattgctta aaaggttgta aagtaaatcg tgaattgcta gaaatagaaa aagaaattta
    32281 taaactttta tcgagaaaat ctataagaca aatactagaa taaaaaattt tcagctatga
    32341 taataattgg aggttttcgg ttatggatga tatatctcaa gataattttc tactgtctaa
    32401 agagtatgag aatagcttag atgtagatac taaaaaagca agtggaatat attatactcc
    32461 taaaataatt gtagattata ttgtaaaaaa aactttaaaa aatcacgata taattaaaaa
    32521 tccatatcca cgaatacttg atatttcctg tgggtgtgga aattttcttt tagaagtata
    32581 tgatatttta tatgacttat ttgaggaaaa tatatatgaa ttgaaaaaga agtatgatga
    32641 aaattattgg actgttgata acatacaccg tcatatatta aactattgta tatatggtgc
    32701 tgatattgat gaaaaagcta taagtatatt aaaagatagc ttaacaaata aaaaggtagt
    32761 aaatgattta gatgaatctg atataaagat taatctattt tgttgtgata gtcttaaaaa
    32821 gaaatggcga tataagtttg attacatagt gggtaatcca ccctatattg gtcataaaaa
    32881 acttgaaaag aaatataaaa aatttctcct agaaaaatat agtgaagttt ataaggataa
    32941 agctgactta tatttttgtt tttataaaaa aattatagat attttaaagc aaggaggggt
    33001 tggcagtgtt ataactccaa gatatttctt agaaagtcta tcaggtaaag atttaagaga
    33061 atatattaaa tcaaatgtca atgttcaaga aatagtggat tttttaggtg caaatatatt
    33121 taaaaacata ggggtatcta gttgtattct aacttttgat aagaaaaaaa caaaagagac
    33181 atatatagat gtatttaaaa tcaaaaatga ggatatatgt ataaataaat ttgaaacatt
    33241 ggaagaactt ctaaagagta gcaaatttga acattttaat ataaatcaga gattgctatc
    33301 tgacgaatgg atacttgtaa ataaagatga tgaaactttt tataataaga tacaagaaaa
    33361 atgtaaatat agcttggaag atatagcaat aagttttcaa ggaataatta cagggtgtga
    33421 taaagcgttt attttaagta aagatgatgt aaagttgaac cttgtagatg ataaattttt
    33481 aaaatgttgg ataaaaagta agaatataaa taaatatata gtagataaaa gtgaatatag
    33541 gctaatatac tcaaatgata tagataatga gaatacaaat aaaaagatac tagatgaaat
    33601 tatagggcta tataaaacaa aattagaaaa cagaagagaa tgtaaaagtg gaataaggaa
    33661 atggtatgaa cttcaatggg gtagagaaaa gcttttcttt gaaagaaaaa agataatgta
    33721 tccttataaa tcaaatgaaa atagatttgc tatagattat gataacaatt tttcaagtgc
    33781 agatgtatat tcttttttta taaaagaaga gtatttagat aaattttcat atgaatatct
    33841 agttggaatt ttaaattcca gtgtttatga taaatacttt aaaataactg ctaaaaaaat
    33901 gagtaaaaat atatatgatt actatcctaa taaggttatg aagataagga tttttaggga
    33961 taataattat gaagagatag agaatttatc aaagcaaata atatcaattt tattaaataa
    34021 gtctatagat aaaggaaaag tagaaaaatt gcagataaaa atggataact tgataatgga
    34081 ttctttaggt atataagcag ttgtaagtat taaaaaatta taatccttta attgtttatt
    34141 taaatttaga aataaaaagt tagccatata aaaaatatta aaaatatata cttttcaata
    34201 tttttttgat aaaataagaa tgaatttgtg caattttatt tttctccaat aactaaaaat
    34261 agttttttga attaatattt gcttaagaat aaaaatcaga aacgtttttg atatagtagg
    34321 tgataatatg aaaggattag ttttagaagg tggaggaaca aaaggagcct accaaatagg
    34381 tgcatataaa gctttaagag agcttggtat agagtttcaa ggagtaactg gcacatcaat
    34441 tggtgcttta aatggagcat atataattca aaatgatatt gaagtaatgg aagatatttg
    34501 gttaaattat gactatactc attttatgaa tattgataga gaaacctatg agaggtttaa
    34561 aaatgtagat ttcactacta aaaatctcaa tgcagtgttt gagcttataa ataaagctag
    34621 aaaaaatgaa ggtatagata taagcccatt aagacaacta atggagacaa cattaaatga
    34681 agacataata aggaaatcaa aaaaagactt tggacttgtt acggtctggt gggataaaaa
    34741 aattaatcca tatccattgt atatcgaaga tatacctaaa ggaagattga ttgattattt
    34801 aattgctagt tccagtttgc ctatttttca aacgaacatg atggatgata agttgtatct
    34861 tgatggaatg ttttgtgata acatgccaat aggactcttg gaagacaaag gttatgaaga
    34921 tgttgttgta attaggttga ttgatgattt tattgggaaa atgaatctaa atcgacatca
    34981 aaatataaat ataaaaacta taataccatc agaatatcta ggaggttctc ttaataaaga
    35041 tagagataat gtagaaaaaa acatccgact aggttactta gatactatga aagcatatga
    35101 aagatgcact ggaattaagt attattttga tgtagagtat aaatataatg aagaatattg
    35161 ttttgataaa tttagaagta tgagcaatga aacaatacaa tatatctgta atttattgaa
    35221 tataaaaaga gatgcttcac ttagaactgt tatggaaagt gtaataccaa agcttggtga
    35281 ggtgcttgga ttgccaaagg acttttcata taaagatttg ttttactgta tatatgaaaa
    35341 gaaacttgaa gaaaataata taaacaggat aaaattatat gattttaaca aggttataga
    35401 tgttgtaaat acaaatattg attctaatag aaatttagct tctaattttg aagttagacc
    35461 taaaattagt attaaaaaga acaaaaacac aaaattattg acaaattgta ttataaaaga
    35521 cataaaaaat caaagttaaa taaaaaacaa aaaaaaattt gtaattatac tcgaaaaaag
    35581 tgtatattag tagtataata tttttgtagc actagtggga acaaaaaatg accataggac
    35641 aaaaaagtac cacttagtac cattaaagta aaaaacagga aaacaatttt aaaaaatata
    35701 aaatgtaaag tttataggag gatttaaaaa atggaaaaag tagttagtat caaaaatgca
    35761 agtggattac atgctagacc agcaggaatg tttgttaaga aggcagctga atttaaatca
    35821 acagtagagg ttgtagcaaa agacaaaact gtaaatgcaa aatcaataat gggaataatg
    35881 agtttaggtt tagctcaagg agaagaatta aagttagttg taaatggaga agatgaagaa
    35941 gtagctttag ctgcaatggt tgaattagtt gaaagtggat ttggagaata gatataataa
    36001 ttttttaaaa tttgatattt agaatctaat attacttaaa gtaaagtaac agagaagtat
    36061 taaacatata cagaccaaca tttgtagata tttaatttct ttgttacttt catgtttatt
    36121 taatcagaag attaagacta ttgttaattg ggtataaaaa tataaatatt ttagaaaatg
    36181 aaataagata tttttaatca taaattcaga gtaaaaatac agtaacaaac agtttataaa
    36241 atttaataaa aaattataag taaataaaac tataaaaatg taaattattt atataaattt
    36301 atagagttta tgtgctagat gatatttttt aggaggtagg gttatggctt acaaaggaat
    36361 aggtgcttct cctggtgttg ctttagggaa agcgttagta gttgaacata gtgaattagt
    36421 aattgaaaaa aaatctatag ataatgttga agctgaaatt gctaaattag aagatgcagt
    36481 tgcagtttct aaagaagaat tagtaaaagt taaggaaaag gcttctgaag aattaggagc
    36541 agaggaagca gaaatatttg aagcacattt attagtttta gaagacccag agttaattgg
    36601 ttctgcaata gataaaatta aaactgaaag tgtaaatgca gagtatgctt taaatgaaat
    36661 aaaagagatg tttgttagca tgtttgagtc tatggacaat gagtacatga aagaaagagc
    36721 ggcagatata aaagatgtta caaatagaat acttagacat atattaggaa ttaaagttgt
    36781 tgatttatct gctttaagcg aagaagttgt attaatagca catgatttaa ctccatcaga
    36841 cacagcaact atgaataaaa aaatggtttt aggattttta actgatatag gtggaagaac
    36901 ttctcatact gctatcatgt ctagaacttt agaaatagct gcaatcgttg gattaaatga
    36961 tataacttca aaagttaagg atggagattt tgtagttttc aatggagaca caggtgaagt
    37021 aattgtgaat cctgatgaag agactataaa taaatatact gaattaaaag ctaagtatga
    37081 agatgagaga aaagcattac agctattaaa aggaaaacca tctgtaactt tagatggaaa
    37141 acatgtggaa ttagctggta acataggaac acctaacgat atagaaggtc taataaagaa
    37201 tgatgctgaa ggtgttggtc tttatagaac agaattttta tacatggata gagattcttt
    37261 cccaacagaa gaaatacaat atgaagcata caaagctgta ttagaaggaa tggatggaaa
    37321 gccgatagtt ataagaacat tggatatagg tggagataaa gaattaagtt atttaagtat
    37381 ggaacctgaa atgaatccat tcttaggtta cagagcaata agactttgcc tagatagaaa
    37441 agatatattt aagactcaat tgagagcttt atatagagct agtattcatg gaagattaag
    37501 aatcatgttc ccaatgattt catctttaga agaattgtta caagctaaag aagttgtaaa
    37561 agaagtttta gcagaacttg attctgaagg tgtggcttat gctaaagatg tagaaattgg
    37621 tatgatgata gaagttccat ctgctgctgt aatatctgat gtattggcta aacacgtaga
    37681 tttcttctct ataggaacta atgatttaat tcaatacact tgtgcagttg atagaatgaa
    37741 tcaaaagata agttatcttt acaatcaatt taatccagct gttttaagac ttataaagac
    37801 tgttatagac aatgcacata aagaaggaaa atgggcaggt atgtgtggag aatctgccgg
    37861 agaccaaaaa atgataccaa tacttttagg tatgggatta gacgagttct ctatgtctcc
    37921 aatatcaata cttcctgcta gaaagttaat aacttcagtt aaagagtcag atatgaaaaa
    37981 attagctgat gatgtactta atatgggtac tgctgaagaa ataaaaagct atatagaaaa
    38041 gacttttaat atataattaa tgttatatag ttactaaaat tcatttttct aaataacaaa
    38101 attatatttt acgaattaaa aaggagatgt ttcaaaataa aaatttgaag catctctttt
    38161 ttataaaaga ttactaagaa ttacttaatc tttgtaatag tcattttgtg aaaaagcaaa
    38221 actgcattgt gactatagta tatatggatg ttattatcaa taaaagtact attaaaatga
    38281 agattcattc tcaaatgata tcaaaagtag ttgtgatgga gtaagataat attttgtgat
    38341 ttaatagtaa aaattaaaaa aatatggtat tgaaaaataa ttaaaagtat ttaataatag
    38401 aattagggaa gaataagttt ataagtaaaa ataattgatt actagttaat aaaataaatg
    38461 tgatatccaa ataaatccta aatctaattt gagttttaat atagatagtc taaagtttga
    38521 ttattaaaga tttaattgta agttgttaca gttgatgata ttgattagag attaaagttt
    38581 agagtagaaa gttaccttaa atttaaaaat gcaagataac ccaatctaaa aattataatc
    38641 actcgatagg tttaaggatt tatttgttta ttataaatag gagggtgtct caaaatgaac
    38701 tttttagttt atgaggcact ctcttttata tagaattaaa tatattttat tatttcaaca
    38761 atgaaaaaga agcttatctc tattttgaga cagcctcttt gtatactatt attaatttaa
    38821 ttaataatat aatttaaaat tataatatta gttaagattt cctgctttat tagtaaataa
    38881 ttctttaata gcattgtttc tggaaactaa atcgttatca gagttgtttg tttttttcat
    38941 aatcactgaa taacgttttt tatttataaa aaatattaaa atcttatcat catcaaaatt
    39001 gtattcttta tatctgtcaa tagactcata acctagattt agaatgtttt tgtcttttat
    39061 actatctaca tctaaaatat atgatgggtc agcctttagt aatatattaa ttaaacattt
    39121 ttcttcacca gcacagaata actccatctt acttgatata gatttagatt gctctgaagt
    39181 tatttttgca ggaataaggt tgtcattatc atctcttaga agataaccat gtgtgtcttg
    39241 ttgatatact aaattaacct ttttcttagg aacactaatc attttatcta aatgtacata
    39301 atgatgattt tcaacaaaac cttcatttaa tatttcaaca aagttattaa ttttacctag
    39361 gcaaaaagat tctatagatt ctttacagaa tttatttgta aatggtatta tgtttacgtt
    39421 ttcctcatct gtattccatg ctatagcata atccaacgaa tatacttctt cctctatatc
    39481 tgcaaaatta tattgtacta tgtttccttt caaaattact cgacctccat cttataatat
    39541 atttaatata ctttataaaa cttatattat atttaaataa tatcataaat tggataaata
    39601 tgatatagta aataagaaaa aatttgaaaa aaatcactat aaatgagtaa taaatataaa
    39661 tagtgtatac taatgggatg gaaaatgtcc actattaact ttattacccc acatatataa
    39721 gataaaatta ttaatataaa atataatcta tcgacaatga atagactttt aaataaactt
    39781 aatataaaat taattaaata agtgcttaaa aacgatttac tttaatgata gaatcatatt
    39841 aaaggaggat aattttatgg atataaagaa taaaattaaa tctatatttt taccagaaaa
    39901 aaatgactat ttagatgatg aagaatttga gtatgatata gaaaataatg aagaagattt
    39961 aaaggaagat aacaaagtac atttaaatga tttaagcaga gtaaaatatg attacagaga
    40021 gttaaaagac atagaaaacc aaacagaaga gatgtgtctg ctagcagtaa agcaggatgg
    40081 tactataatt gagtttgtaa aggacaagac ttataaagta tgtatggaag cagtaaaaca
    40141 gacatataaa gctcttaagt atataacaaa tcaaaatgag gatatttgta tagaagcagt
    40201 aaaacagaac tacagagctt tgtactacat aaataataag acagaaaatg tactaattga
    40261 ggctataaaa aatgcatcaa cttatgatgt catggaagta tttaaatttg tggaagatca
    40321 aacagaagat gtatgtctag catttataga aagggcatct aaaaatgatg ttgcagagat
    40381 attaaaagga ataaaagagc aaactccagc catatgttta gaagctgtaa aaaaagatgg
    40441 aaaatcttta gcttatgtaa aggaacaaag taatagtata tgtttagaag ctgtaaaaga
    40501 aaactacagt gcactatctt gtgtaaaaga gcaaacagaa gaaatatgta tagaagcagt
    40561 aaaacagaat gactttgcat tgtattatgt aaatgaacag acagaaaaaa tatgtatgga
    40621 agcagtaaaa agaagttata tggctctaca gtatgtaaat aagcaaacag aagagatttg
    40681 tttggaagca gtaagaattg atggaagagc attacagtac gtaaaagagc aaacagaaga
    40741 aatttgcttg gagtcagtta gacaaaatgg aaaagtattg caatatgtaa aaaaacagac
    40801 tgaaaatata tgtatagaag cagtaagagg ttcatttgaa gaacttgaaa taaaagaaat
    40861 attaagttat gtaaagatac caacagaaag aatatttgta gaagcagtaa agcaaaatgg
    40921 aaaaattctt aaatatgtag aaaatcagac agaattaata tgtttagagg cagtaagaga
    40981 aaactataat gctttagctt atgtaaagga acaaacagaa gagatttgtt tagaagcagt
    41041 taatcaaagt tatgaagcgc ttaaatatgt gaaagaacaa acagaagaag tttgtctaaa
    41101 agcagtaaaa caagattata gaatgttgaa atatgtaaat aatcaaacag aaaaaatatg
    41161 tttagaagca gtaaagcaaa attatagagc tttagaattt gttgataatc aaacagaaaa
    41221 agtttgtctt gaagcagtaa aacagaatag aaaagcacta cagtatgtaa aacaaaaaca
    41281 aagttaaaag gctaaaatat atagaaaata tatgcaaata aataaaattt gatattttgt
    41341 aataaataaa atgggtatct caaaatgaac tttttagttt gtgaggtact ctttttatat
    41401 gaaataaaat atatttttag ccttttaaca atggggaaaa ggtttatttc tattttgaca
    41461 taggcttttt atgcatataa agcttgataa aattgtttta ttataattgt tttgttatat
    41521 aaataataat aagaaaatta tataggtctt tttttgacca gttttgcatt tttaacaact
    41581 agttttgtaa agtatattga attttctcaa aaaagaatgt actctatata tgtaaaattt
    41641 ttttggaggt aaaaatgttt aaaagatatg ctgaaaaaat gacatctgtt ttaatttgta
    41701 ataatatgat agataataat gaatctaaag tctattctta tggatttgaa atattaatag
    41761 ctttcatagt taatataacc accatgctgt ttataggttt tttatttggt aaatttacat
    41821 atgtattatt ttttttaatg tgttattgtc caataagaca attttcagga gggtatcatg
    41881 cagacaatta ttttagatgc ttattaacct ttatttttat aattttatct acaatcttaa
    41941 ttatagaaaa tataaatata gacttattta aaaatattat tatgattatt gcaagtgtta
    42001 gttgggttgg aatttgtgtt ctgtgtccaa tagaacatag gagtaaccct ataagtgata
    42061 gggaaaagtt tgtttataag aaaactgcta tatttatatc tacagtagtg ttattgataa
    42121 caattttaag tctttctttg agtatatttg tagattattt cacatatagc gcatttgcca
    42181 tgttttggat ttttgtgatg ttagtattag gtaagttaaa agctaaagta taagtaaaat
    42241 atgtatgagg gagagttaag ttatgaaaaa gtttattgta agatttatga agtttgctag
    42301 ctcattggca cttagcactg ctattttgtc agctaatagt acctgtcctt ggattattca
    42361 tcagcctaaa gtacccaaag aaatcagcaa tctaaagaag acaaattaaa tacaagcact
    42421 tatttataca aaattatcag gaaaaaagaa attattatat tttaataaga ttaaaacaat
    42481 ataaaatcag atacaaaatt tattttattt attttatagg agcctaatac ctatttggta
    42541 atatattagt gcgccaattt agggggatat agtgtattta atgaaatgac ttacggagag
    42601 taagtcattt ttgtattgta tgtattttat gtaaacttat gatataatga agggtaaagt
    42661 ttaattaaaa taataaaaaa ctttagtata gatagtaatt taggaggtag ggtatgagta
    42721 tgatacataa attttctatg aatggatata atatcgtttt agatgtgaat ggtggagctg
    42781 ttcatgtgtt agatgatgtt gcatacgatt tgttagattt ttataaagaa aaaagtaaag
    42841 aagaaatatt agagatatta aaatcaaaat atcaagaaga aaaaataaat gaagcatatg
    42901 aagaaatatt aaatttggaa aaagaaggtc ttttatacac agaagataca tatcaatatc
    42961 atccaagctt tgtacataga gagcctgtag taaaagcttt atgtttaaat gtagctcatg
    43021 attgtaactt aaaatgtaaa tactgttttg cagctcaagg tgattttgga ggagaaaaag
    43081 aacttatgag ttttgaagtt ggtaaggcag caattgacta tttgattgct aattcaggaa
    43141 gtagaaagaa cctagagata gatttctttg gtggagagcc tttgatgaac tttgaagttg
    43201 taaaacaact ggttgactat ggaagaagtg tagaaaaaga ttataataaa aatataagat
    43261 ttacaataac tacaaatggt gtactgttaa atgatgagat tatagattat ataaatgaaa
    43321 atatgcataa tgtagtttta agtttagatg gaagaaaaga agttaatgat aatatgagac
    43381 caactttaaa tgataaagga agttatgata ttacattacc acgatttaag aaacttgtgg
    43441 aaaaaagagc aaaagataag tattattata taagaggtac ttttacaaga gataatttag
    43501 atttttcaaa agatgttatg cattttgcag atttaggatt taaattaacc tctgtagagc
    43561 cagtcgttgg agatgagagt aatccatatg cacttagaga agaagattta cctaagatat
    43621 ttgaagagta cgaaaaattt gctgtagagt atgcagatag acaattacaa ggagatggat
    43681 ttaaattttt ccattttatg atagacctaa atcaaggtcc atgtgtaata aagagaataa
    43741 ctggatgtgg agctggaaat gagtatcttt ctgtaactcc aaatggagat atctatccat
    43801 gtcatcaatt tgttggaaat gaagaattta aaatggcaaa tatatttgat gaagaaatag
    43861 tacttccaga aaatttaaaa aatatgttta gagaagctca tgtatatact aaagaagagt
    43921 gtaaacaatg ttggaataag ttttactgtt caggtggatg tcatgcaaat gcgataaact
    43981 ttaataatga catatcaaaa ccatatgaat taggatgtga aatgcaaaga aaacgtacag
    44041 agtgctctat aatgatacaa gctaagttaa tgttagaagg agcaaccaac taaatttata
    44101 ttttaaagga gttgtttata tatgattaga gattatttag aagataaacc tttaattgac
    44161 gaaagtgtat ttgtggcaaa atcagcagat gtaattggaa atgttaaaat aggcaaagat
    44221 tcaagtatat ggtacaatgc agtagttagg ggtgatgaag gaccaataac tattggagaa
    44281 aacactaata tacaagattg ttctatagtg catggagata cagaaactat aattggtaac
    44341 aatgtaacag ttgggcatag gtctatagtt catggttgta aaattagtga taatgtgtta
    44401 attggtatgg gttcaataat attggataat gctgaaatag gagaatatac tctgatagga
    44461 gcaggtacac taattacatc taataagaag tttccaccag gtgttttgat aatgggttct
    44521 cctggtaagg ttgttagaga gcttacagaa gaagataaaa aatatattga tgaatcttat
    44581 gaatggtatt tagaggcagc acaaaatcaa aaatattagt ttaaagagtg gttgtttcaa
    44641 aacatattta aatctgtttt gaggcaacca ctaatttatt ttattagatt ttgttgatat
    44701 tttagttttc aaaaagtatt tgattaaacc agatataaaa tgtcaaaaat aaaaattaac
    44761 tgagttaaat aattttaata aaattggtag tatatgtgat aaaattaaat attaaagagg
    44821 atataggata ttagaatatc aattggtgaa ataatgtcat atacgataaa ttaaggtgta
    44881 agtttttggg tatacctatc ttaggagtga aaagatttga gaataagtta tagaaattta
    44941 aagcgatata gagaaattgg atatgtttta ataaagtatg gttttagttt tattgtagaa
    45001 agactaaata tagaaggaat tgcctataaa ataccactat ttgacccacc agaagaaata
    45061 aaaaatatga caactggtga gagaatgaaa agagttttag aagaactagg acctacatat
    45121 ataaaaatag gacagatatt gagtacaaga aaagacttgt tagaccagga tataattgat
    45181 gaaatatcaa aactcagaga tgatgtagag aaatttgatt caaatatagc tattgatata
    45241 tttaaagaag aagtgggttt aagtatagaa gaaatattct tagaatttaa agaagaacca
    45301 atagcagcag cttcaattgg tcaagtttat gaaggtgtac ttaaaacggg agaagaagta
    45361 atcgtaaaaa ttcaaagacc aaatatagag aaaataataa aatctgattt agagattctt
    45421 agaactattg caaatacttt aaaagattta aaaaaggatt ttaatttaga tttagtacag
    45481 atgattgaag aatttcaaac tcaattaatg agggaacttg attatacatt tgaagccata
    45541 aatgcaacta aattctctag gatatttaaa aatagtgatg aagtatatat acctaaagta
    45601 tactcagaat ataatactaa gaaaatttta gtaatggaga aagttaatgg tacaaagtta
    45661 agtgatgtag aaaaaataag gagactaggt tataacacaa aaactattgt tgaaatagga
    45721 gttaggtcat tttttacaca ggtattatct catggatttt ttcatgcaga cccacatcca
    45781 ggtaatatat ttgtagttgc taaaaataag atagcatata tagattttgg aatgattgga
    45841 attattgata ataaaacttt aaaccaatta aatgaaattg cattagcagg tgtagaaaag
    45901 aatgttgaca agataatata tctattgata gaaatggatg cattaaatgg agaggctgat
    45961 attaagggac ttagacagga tttactttat ctaatacatt attactatga tatttctata
    46021 gaaaaaataa atgtaacaga tatattaaat gaactattta ggttttttag acagtataaa
    46081 atagtcatgc ctgcacaatt tgtaactctt gcaaagacag ttataacatt agaaggaaca
    46141 agtagaactt taaacacaga tttttctttt ggttctatgg gaaaagagtt tatgaaacat
    46201 cattataaga gtaaatttaa ccctaaaaat gttgttttaa gttcaagaca aaatgtagaa
    46261 gaaatattac tggacataaa aactattcca aagcaattaa aagcaatttt aaaaaatata
    46321 gaaagaaata atataaaaat gcaaattgaa gatgttaaaa tgacgaggtt agaaaattgt
    46381 ataatagagc taacatctca aatatctttg agtttagtgt tggcatctat tatagtaggt
    46441 tcttctctta taattgcatc tccaaatata gaaaataata tatggataaa atttactgca
    46501 atagcgggtt tctttatatc ctttataata ggcctttgct tagttataag aagtattagg
    46561 tcaaaataca aaaaagatta gggggaatta aatttgaaaa aatggatatt gaagtataaa
    46621 ggtaagatag aggaaagtga atttagcaaa aaacttaata tttccccgga aatctgccaa
    46681 attttaaaaa atagagggat atgtactgaa aaagattcag aaatatttat gaatccatct
    46741 ttagattatt taagagaccc ttttttaatg aaagatatgc aaaaagctgt tgatagaata
    46801 aagttagcag ttgagaagaa cgaaaaaatt tggatttacg gagattatga tgttgatggt
    46861 gtatcatcta catccatctt gtgtttatat tttaagagta taggttacaa tgttgattac
    46921 tatattccta atagattaga agaagggtat ggtataaatg aggatgctat taagcttata
    46981 agctctaggg gatgtgactt gattataagt gttgactgtg gaattacatc agtgtctgag
    47041 gtcaatacag cgaatgattt gggcatagat gttataatta cagaccatca tgaatgtcaa
    47101 agtgaaattc catcagcctt tgcagtaata aatccaaaac aagaagattg taattatcca
    47161 tttgattcac tatgtggatg tggtgtagca tttaaaatga ttcaagcctt gactccaaaa
    47221 gaagaattta aaactagtat gtataattat ttggaaatag taacactagc aactatttgt
    47281 gatattgttc cacttataga tgaaaataga ataattgtaa aaaatggttt aaaatcaatg
    47341 aaagaaggca aaaatattgg attaagggag cttataaaag tttgtggtgt agaaagtgat
    47401 aagataggtt cttctcatat aggttttgca ataggtccta ggataaatgc ttcaggtcga
    47461 ttgggatatt cttacttagg agtagagcta tttactactc agtcacaaga agaggcagta
    47521 gaaatagcta gtatattgga agaaaaaaat aatgaaagac agatgataga agctaagatg
    47581 tatcatgaag ctgaagaaat gctaaagtct aatagcagat acaatgatga caaagtgttg
    47641 gttttagcca aagagggttg gcaacatgga ataataggaa ttgtagcatc aaagttaact
    47701 gaaaaatact acaaaccaac aattcttcta ggtatagaaa atggggaggc tactggttca
    47761 gcgaggtcaa taaaaggatt taatatattt gaagctctca taaagtgcaa agacttgatg
    47821 actaagtttg gtggtcatga acaagcagca gggttatcct tggattcaga caatgtagaa
    47881 attttagcaa atgaaataaa taaatttgca gattataatt taactgaaga tgatatgata
    47941 gagaatgtaa atgtcgagtt tgaattacaa gaaaatgtaa taaatttaaa tcttgtagaa
    48001 gaattacata agttagaacc ctttggatta aataatccta atcctagatt tatagttaga
    48061 aattatattt taaaagattt gaaagttata ggtaagaatc aacaacatct gaaattaagt
    48121 atagaaaaag agaaaagcta tgaatgtata ggatttaata tgagtcattt aaaatcaatg
    48181 tataaagtag gagacaaagt agatgtacta ttccaattag atgaaaataa ctatatggga
    48241 aataggaaag tacaattttt acttaaagat atacgattgg ctcgacctaa aagtgcaagt
    48301 aatgacaaac tttcattgaa attaatgtca aaaataatac caaaagatac tcaaagcctg
    48361 tataatatat ctgtgtctga ttttgaatta tttgatggaa atacagatat aaatatattt
    48421 gattattttg aaaaagatac actaataata tctaattcta taaatggatt ttatagagca
    48481 atgtcagata tatcacttat agatttggat tttaacataa attacaatat tattgaagat
    48541 gttagcaaaa atactgataa attagagctt atattttctc ctaatattga taaaatagac
    48601 ttaaaaagat ataataatat tattctttat gattatttat acaataaagg cgaatattcg
    48661 tatatatatg agaataaaag agaagaaagt gaaattataa aatattataa taaaacagac
    48721 ctattatatt taaagaatgt agttagtaat atagttccat caagagatga atttataaca
    48781 atttataaac aagcacttat aaaaaaagaa attgatttgg atatggtaaa tataagggaa
    48841 acttttaatg taattccatt aaagtttttt acgatattaa atgtatttag agaattaaat
    48901 ttacttgact ttaatttaaa ttatgaaaaa aattctgtac tcataagaat attgccaaaa
    48961 ccacagaaaa aattagactt aaatgagagt ttaatactca ataatctaaa aaatttagaa
    49021 aaacaataca atagcagtta ttaggaggcg tttcccatgg atttaaaaaa ctttataagg
    49081 aatattgatg atttcccaaa accaggcata gattttaaag atgtgacaac tctatttaaa
    49141 gatggagatg catttaaata tgcagtggat tctatagttg aagaattgaa agataaagat
    49201 gtagatttag taatagggcc agaagcaaga ggatttttga tgggtacacc tgtagcatat
    49261 gctttaggag taggatttgt tccaattaga aaacctggaa agttaccagg tgaagttgag
    49321 agttatgagt atggattaga gtatggtaca gatactttag agatacataa ggatgcaatt
    49381 aaaaagggtc aaaaagtagc aatagtagat gatttattgg ctactggtgg gactatggaa
    49441 gccgctgcca agcttgtaga aaaattaggt ggagaagtag tttctatgca atttttgatt
    49501 gagctaaaat tcttaaatgg gagagaaaag ttgtctaact atgatgttaa ttctcttata
    49561 aaatactagt acttttataa tagttggtat aacaccaact attttcatat atattaaaat
    49621 tttatacaaa ataggtggtt atatgcatga taaagaatta caagaaataa ttgaaaaaat
    49681 aaaagtttat gcacctaatg caaattttga aatggttgaa aaagcctata atcttgcaaa
    49741 aaaagcgcat gaaggacaat atagaaaatc tggggaacca tactttattc atccattagc
    49801 agttgcaaat attttaatag agatggaatt agatattgaa actataacag caggtttact
    49861 tcatgatgtt gtagaagata cagaatatac ctatgaagac ataaaaaaag aatttggcaa
    49921 agaagtagcg gatttggttg atggagtaac taaacttggt caaataaaat atcgttcgaa
    49981 agaagaaact caatctgaaa atttaagaaa aatgtttttg gcaatggcga aggatataag
    50041 ggttatactt ataaaacttg ctgatagatt gcacaacatg agaacattaa aatacatgcc
    50101 tccagaaaaa gcaaagtata aagcaaaaga gacacttgaa atttatggtg gtatagctca
    50161 tagattagga atttccaaga taaagtggga actagaagac agagcattaa gatttatgga
    50221 cccagaaggg tattatgatt tagttagtag agtatcaatg aagagaagtc aaagagagga
    50281 ttatattcaa ggaattgttg aacttcttaa agataagttt aaagatttaa gtataccatg
    50341 tgatgtatat ggtagaccaa agcattttta cagtatatat agaaagatgc aaaaaaaaca
    50401 taagactttt gaagagattt ttgatttaac agcagtaagg atattggttg ataatgtaaa
    50461 ggattgctat gcagtacttg gtatagttca tacattatgg agacctattc caggaagatt
    50521 taaagattat atagcaatgc caaaacccaa tatgtatcaa tcattacaca ccactgttgt
    50581 aggtcctgat ggagaacctt tagagataca aataagaact catgagatgc ataatatagc
    50641 tgaaaatggt atagcagccc attggaaata taaagaaggt atctctagca aagagtcaaa
    50701 ggttgaagaa aaacttcaat ggttgagaca gatgatggag tgggaaaaag atttaaaaga
    50761 cccacaagag tttatggatg cacttaaaga agatgtattt aatagtcaag tttatgtatt
    50821 tacgccaaaa ggagacgtaa ttgaattacc agcagaatca acacctatag attttgccta
    50881 tagagttcat acaaatgtag gtaataaatg tgtaggagct aaaattgatg gaagaatagt
    50941 tcctattgat tataagcttc aaaatggtaa tattgtcgag gtacttacat catctaattc
    51001 taatggacca agtagggatt ggcttaatat agtgaagacc ccaaatgcaa aaagtagaat
    51061 tagacaattt ttcaagaagg aaagaagaga agaaaatgtt gaccgtggaa atacaatatt
    51121 agaaagagaa tttaagaagc atgatatacc acaaaaagac cctcttgttg aaaaatatat
    51181 ggcattagtt gctaagaaat ttaatcagcc aagtgttgag gacttaattg ccactgtagg
    51241 ttatggcggt ataatgtcat ctcaagtggt atctaaggta aaagacctat atttaaaaga
    51301 ggttaaaaaa gctaaaaagg aacaacagat acaagaagaa gatttaaata aacacaatat
    51361 aagtgaaaca gaatacagta aaaagagaaa gaaaaacgca tcacaaggaa ttatagtaaa
    51421 agggcttgac aatatcttag taagatttgc taagtgttgt aatcctcttc caggagatga
    51481 aattgtagga tatattacta agggtagggg agtagccata cacagagctg attgcccaaa
    51541 tgcaaacaat aatggtgatt tcttccaaaa tagattggtg gaggtttcat ggagttcagc
    51601 aggaaaaggt aagtttgaag cggaaattca aataaaagct attgacagaa gaggaattgt
    51661 taatgaaata actcatattg ttgcaatgga taaacttagt ttaaacggaa taaatgcaag
    51721 aaaaggtaag gatagtattg taagtataaa cttacttgta gaggttaatg acacagagga
    51781 attaaaaatt ctaatgaaaa aattaaaagc aattcctggt gtagaaagta tttatagaat
    51841 gacaaattag agttaaaata atagggagga aactatgaga gcagtagtgc aaagagtatc
    51901 ttcatctaaa gttacagtag atgaaaacac tataggtcaa ataaataagg ggttactagt
    51961 attgttagga gtgactcatg atgataaatc aagtgatgta gattatatga ttgataaaat
    52021 attgaatctg agaatttttg aagatgaaaa tgacaagatg aatttatctc taatggatat
    52081 aggtggagag cttttagtag tatctcaatt tactttatat ggagattgca gaaaaggaag
    52141 aagacctgga tttagtaatg catctagacc agaacttgca aataaccttt atgaagaatt
    52201 tgtaaaaaaa gcaaaagata aaggtgtgac agttggtaca ggtcaatttg cagctcatat
    52261 gatggtagag ttaactaatg atggtccagt aacaatacta ttagactcaa gtaaatcttt
    52321 ttaaggggga aaactttaat gattataaaa aaatttgtag atagttattt tggagtaaat
    52381 acttatgtat taggtgatga aaagactaaa aaatgtgcag ttatagaccc aggtggaagt
    52441 ttagtagaga cattaagttt tgtaaaagaa aatgaattaa atattgaata tattatcctt
    52501 actcatgggc atggagacca tataggatat gttaaggata ttaaagaaaa aactggtgct
    52561 aaagtagttg cacatgttga tgaaaaagaa ttattaaatg ataaaaataa aaatctaagt
    52621 tatacaatga gatgtggagc gcaagagttt gatgcagata tctatgtgag tgataaagac
    52681 aagcttgaac ttggtgaatt aaaaatgact ttcttgcata ctccaggaca tactcaagga
    52741 tgtatgtgta taagagttga agatgaaatg ttcacaggag atactttgtt tgctggaagt
    52801 attggtagaa ctgatttata tagtggagac tttaaccaaa tggaaaaatc acttaagaaa
    52861 ttatgcaaat atgaagatgc tgttagagta tatcctggac atggaccaac cagtactcta
    52921 ggggttgaaa agaagacaaa tccttacatg taattttata ttagtattta aaaaagtata
    52981 aaatatttaa taactatatt agtgaggggg ttcttctact gttaaataga aggagttaag
    53041 ttgatgttgt atgttttttt aaaaggacat gattataagt atgaagtagc agaacttata
    53101 aaattgttta ccagtgaatt taagtttaaa gactctaatg ctaacaataa tatagagtca
    53161 aagcatttaa taaatagatt gatttatgag aatggtgtat tattctcaag tactgaatac
    53221 tatgaaaatg gaaatttaaa gtacgagtca atacagaata tagaaaatat gaatcttgaa
    53281 tttttagatg gatttgatag tagcaaaacg attgaagaat ttcttaatag actagatagt
    53341 gaaagtaaga ggaactttaa aaagctgtgt aaagaaaata tcaaaaaaag catgtttgta
    53401 gtgcttaaac aagtatttaa ttcttatgta ccatggggaa ttttgactgg tattagacca
    53461 gtcaaaattg tccacaattt aatggataaa aagctagatg ataatagcat aagaaccatt
    53521 ctaaaagata attattttat aatagataag aaaatagatt tagctcttga aatagctaaa
    53581 agagagcgat tatttatgta tcctatagat aaaaataaaa tttctcttta tgtaagtatt
    53641 ccattttgtc caactagatg tgtatattgt tcatttcctt caaattcatt aaaacaattt
    53701 ggacatttaa aaagagaata tgtttataaa ttgattgaag aaattaaggg gtttgccaaa
    53761 gttattaagg agactaagaa agaagttgaa actctatata ttggtggtgg aactccaact
    53821 acacttgatg aggaagaatt agatttgctt ataaattcat tgttcaatga attagattta
    53881 agtaaaatta aagaatttac tgtagaagca ggtagacctg acactattac agaacaaaaa
    53941 ctaagagtgt taaaaaaaca caatgttagt agaattagta taaatcctca aactatgaat
    54001 gatgatacct tggtaaagat tggaagagag catagagtat ctgatttagt agattgcttt
    54061 aatatggctc gtagaatggg atttgataat ataaatatgg atataatttt aggtcttata
    54121 gatgaagaat taaatatggt aaagaacaca ttggaggaga taaaaaaact ttctcctgaa
    54181 agccttacag ttcatacatt agccataaag agagcatcca acttaaatat aaatatggat
    54241 aggtataaag aacatctaac acaatatgaa gaaatggtaa aaatgataga tttatcaatg
    54301 aaatatgcaa aagatatggg attaaatcca tattatatgt acagacaaaa acatatgttg
    54361 ggaaatttag aaaatatagg ttatgctaaa gaaggatatg agtgcattta taatatacag
    54421 attatggaag aaaaacaaag taactatgca ttaggtgcag gtgctatatc gaaatttgtt
    54481 tatgtagatg aagatagaat tgaaagagta gaaaatgtaa aaaatgttga acaatacatt
    54541 gaaagagtag atgaaatgat aaaaaggaag aaagaagagg tatataaaaa tgttgactaa
    54601 agctcctaga ggaactaaag acataactcc aaaagaggct tacaaatggc gttatgtaga
    54661 aaataaattt agagaaatat gtgctttata tggatatgaa gaaatggtaa cacctatatt
    54721 tgaacataca gaacttttca agagaagtgt tggagatact acagatatag ttcaaaaaga
    54781 aatgtattct tttaaagata aaggtgatag agaaattacc ttaaagccag aaggtacagc
    54841 aggtgtagta agagcattta tagaaaataa attatatgca gatactcaac caacaaaatt
    54901 attttatgtg acaccttgtt ttagatatga aagaccacaa gctggtagac aaagacaatt
    54961 tcaccaattt ggaatagaag cacttggaag tgatactcct tcaatggatg ctgaaataat
    55021 cgcactagct gttcaatttt ttaatgaagt tggattaaat gatttggtag tgagtataaa
    55081 ttcagttggc tgtccagttt gtagaaaaga gtacaatgct ttattaaaag agtatcttga
    55141 ctcaaaagct gatatattgt gtgatacttg caatgagaga agagaaaaaa atccaatgag
    55201 ggttatagac tgtaaaaatc ctacatgtaa agaaaatatc aaagatatac catttattgc
    55261 agaccatttg tgtgatgatt gtaaatctca ctttgataaa cttcaagaat acttaaagga
    55321 aatgaatata aactttgtaa ttgataaaac aatagttaga ggcttagatt actatagaaa
    55381 aactgctttt gaaattatat ctaatgatat aggagctcaa agtactgtat gtggtggagg
    55441 aagatatgat ggtcttgttg aacaattagg aggaccaaaa ggtataagtg gaattgggtt
    55501 tggactagga attgaaagac ttttacttac acttgaaggt aatggaattg aaatagaaaa
    55561 ccctcaatct acggatatat ttatagtaac tataggtgaa gaagcaaata caagaagctt
    55621 taaattatta aaagacttga gacaaaatca tataagtgca gataaagacc atatagagag
    55681 aagtgttaaa gcacaattta aatattcaga taaaataaat tcaaaattta caatagtgat
    55741 tggagatgat gagcttaaaa atgacactgc gacattaaaa aatatgaaaa catcagagca
    55801 aactactgta aaattaagta cattagttga agaattaaag caaaagctgt aaaataagaa
    55861 agtatgatgt tttgtgtatt agataaatat atagcattaa aattaaataa aatggaggta
    55921 gtatcttgga aactttaaag ggtttaaaga gaactcacta ctgtggagag ttgagagaaa
    55981 aaaacataaa tgaagaagtc gtacttatgg gatgggtaca gaaaaaaaga aatttaggtg
    56041 gtcttgtatt tgttgattta agagatacaa gtggattatg tcaaatagtt tttgatacag
    56101 atgtagataa agaagctttt gaaaaagctg aaaaattagg ggctgaattt gtaatagctg
    56161 taaaaggaaa agtatgcgaa agacaatcta aaaaccctaa tatgccaact ggtgatatag
    56221 aaatatttgc aactgaactt agacttttaa acaagtcaga aactccgcct atttatataa
    56281 aagatgatga tgatgtttct gaagcactaa gattaaaata tagatactta gatttaagaa
    56341 aaccatctat gcaaagaaat ttaaaattaa gacataaagt aatgaatatt acaagaaatt
    56401 acttatcaaa caatagattt tgcgaaatag aaacaccatt tttaatagct ccaacaccag
    56461 aaggagcaag agattatcta gtaccaagta gagttaatcc aggaaaattt tacgcattac
    56521 cacaatcacc acaattatat aaacaattat tgatggtaag tggtatggat aggtatttcc
    56581 aaatagttaa atgctttaga gatgaagatt taagagcaga tagacaacca gagtttacac
    56641 aaatagactg tgaaatgtct tttgtcgagc aagaagatgt tatgagtatg attgaaggtt
    56701 tgcttgaagc gatatttaaa gaagttttag atgtagaatt ggcacttcca cttcctaaga
    56761 tgacttatgc agaagctatg tctaaatatg gttcagataa accagatact agatttggat
    56821 atgagttaac agatatatct gatgttgttt gtaactgtgg atttaaagtg tttgctgatg
    56881 ctacacaacc aggaaaaagt gttagaggta taaacgtaaa aggcaaagct gacgacttta
    56941 ctagaaaaca aatatcatca ctagaagaac atgctaagac atatagagca aaaggtcttg
    57001 cttggatgaa agtaggacaa gaaggagtaa cttctccaat agcaaaattc tttaatgaag
    57061 aagaaatgaa cgctatactt acaaaaatga atgctgaagt aggagattta cttttatttg
    57121 tagctgataa aaactcaata gtatttgatg ctttaggaca agttagactt gaagtagcaa
    57181 ataggcttaa tctattggat aaaaatgtat ataacttact atgggtaact gagttcccag
    57241 tttttgaaga agatgaagaa acaggcacat tttcagcaat gcatcaccca tttacatcac
    57301 ctatggatga agatttagac aagttagaag aaggtgataa gtcatcttta agagcgaaag
    57361 cttatgatat tgtattgaat ggttatgaaa taggtggagg aagtgttaga atatcaaatt
    57421 ctgatattca atcaagaatg tttaaagcac ttggtttcac agaggaaaga gctaatgaaa
    57481 agtttggtta tttattagaa gcatttaaat atggtactcc tcctcatgct ggtctagctt
    57541 ttggtcttga tagacttgtt atgttacttg caggaactga taatataaga gaagttattg
    57601 cattccctaa aaatcaaaat gctgtttgcc ctatgacaaa tgctcctaca ttggcggaag
    57661 atgagcaatt agaagaatta agtataaaag ttgatataaa agataatgaa taatatgtag
    57721 ttgcaagaaa ctaaaatgta aaaagtctgg atataaagta tatttatatt cagacttttt
    57781 ttattagaat tattttatat tttttctcta tatattttca taaattatcc ttgtattctc
    57841 agccaatata attaaaatac tatgtttaaa aattttacat aaacttgatt gttttagaaa
    57901 ttacttctgt aatgagtaca cgattttaat taaagaatat ataacaaatt tgaaataagt
    57961 ctaatatatg acttaataga ttaaattaaa ataataaatt tggactattt atctatttat
    58021 aacttaaatt atatcaaatt gataacaaac tagatattat acttttttgt agaatagaat
    58081 tacaattata taaagaaaaa ttctattaat agtgaaaaaa aagtagaaaa aagtagaaat
    58141 tattctttta taaagaaagg gagggataat attgcaagag agagaagaat tagttttaaa
    58201 tccagttcca aaagaggaaa gagttggatg gttagctcca ttgtttaata tgcttggttc
    58261 taacatagct atatctgaac taatggttgg aggaacttta attttaggaa tgactctttc
    58321 taatatgatt attacatcaa ttatagggaa cttaatatta gttgcaatca ttatgataca
    58381 aggttatata ggttacaaag aagggttaaa tacgtatgta ttagctaagg gggcatttgg
    58441 agagatagga ggaaagtatc ttatatctct attacttggt ataactagtt ttggatggtt
    58501 tggtgtacaa gcaggggttg caggactatc agtacaaaag atattcccaa gtgtaaacct
    58561 aacattagtt acagttatac ttggattatt tatggttgtt tttgcactgt atggctttaa
    58621 agctatggct aaatttaatt acttagttat accaccactt atgatattaa tggtgtgggg
    58681 agtttttaaa gctttttcta cttatggagt tgaagctatt tataattata ctcctcaaac
    58741 aactatgagt atggttgaag gtcttaatat tgtagtaggt cttgttatag ttggtgcaat
    58801 tatatcacct gaccagttaa gatatacgag acgagtaaaa gatatttgga ttatcagttt
    58861 tttaggtcta gggattattt cattattcca acaagttgca gctggtgtaa tgtctatggg
    58921 agcacctact tgggatataa cagaagtatt ggctaattta ggttttggat gggtagcgtt
    58981 tgttatttta atacttgcat cttggtcaac aaacgtatca aatgcttatt ctggtggatt
    59041 agcattaaaa actatttttc caaatgtaaa aagaaatgtt ttgactttag ttgcaggtct
    59101 aataggtaca ataatagcag ctactggtat aatatttaaa tttcagtcat ttttatcttt
    59161 cttgggaatc gcagttcctg caatagcagg aattatgtgg tgtgagtatt attttataca
    59221 aggaagaact tataagcata gagaaggaat aaattggatt gcagtaataa gctggttaat
    59281 aggttttgca gcgtcgtatt atagttcaaa aataaatttc ttaatacctc cgataaatgg
    59341 aattgtagtg agtatggtta tttattatat attaatgaaa tgttttggaa tcaaagataa
    59401 ataaaggggg caattacatg ggtcgtaagg tgaaaatagg tataattcaa caacacagtg
    59461 tacttggaga tgttaaaaaa aatatagaaa aagcagtaga gatgatagat gacttaggaa
    59521 aacatggggc agatataatt tgtttaccag aactatttgc tacaggatat aatttagagt
    59581 ctttaggtgg agttaaaaca ttagaattaa taagagaaca taataagtac atagaggaat
    59641 caatgtcaga agctgctaaa agaaataatg tatacctgat atctccatat ggaaccttag
    59701 aaaaagggtc tacacatgtt tataattcag cagttatatt tgatagaaaa ggtaagatta
    59761 tgggagaata ctgtaaaaat catctgtggt cattagaagc agtatacttt aaaggagggg
    59821 aaaaagtaga ggtatatgat gctgattttg gtagatttgg tgtaatgata tgttatgatg
    59881 caggttttcc agaagtatcc agagaattga cattaaaagg ttctgaaata atatttatac
    59941 catctgcatg gagaatacaa gatgaagata tgtgggattt aaatgtatct caaagagctt
    60001 tagagaacac tgtatataca gtaggtgtaa atttagtaag taatgactct aatttaatac
    60061 tatttggaaa gagtaaaata tgcaatccta gaggtactgt aataactcaa ttagatacat
    60121 acagggaaaa atatgtatta tcagagattg atttagatga aataaaaaag tatagggaag
    60181 atatacccta tttgaaagac agaaaaagta gctataacat ataattctat actataatac
    60241 aagttcaata taaaatgata aaaagaggat gtatcaatat taagattaaa tttattatat
    60301 tttgatatat cctctttaat attatcaact ttgatttaaa tatttttaaa atagttgata
    60361 agaaagtttt tgaacaacaa cacagcttta gattcatagt tttcgctaaa ccatgaaaga
    60421 tttaaatatc ttttaaattc aatatctttg atatgtaaca acttaatctc agggtcttga
    60481 gataatcccc atgattttcc acatataaat ccaactcctt gaagtgattt tataagagca
    60541 taaattgtat atggtgaatc agactcaaat gctattttgg gtttgaaatt agctgattcg
    60601 cacaggatat caattacctc tctataattc tcacccttcg ttataactat aaagttttca
    60661 tctgaaactt cgcttagata tacttcatcc tttaatgata aaggatggtt tattgaaact
    60721 cctaatagta tttcttcgca tgttaaagtt atgctatttt ctgagtttag ctttgtaaat
    60781 gaagaagata tgtacaaatc aaaatcactt tttttataag atgatggcaa agtatgtgac
    60841 acattaaaag taatattggg atatagtttt ctgaaattac tcaaaagtga tggtaacaca
    60901 ttagccgctg caggagataa tatctttact tctcctgaat tttctaaaga agtgtcttgt
    60961 aactcctttt ttgaactttc tactaaatct aaaatgctat ctactctttt tagaaacaat
    61021 cttccatact catttaaaac aatatatctt ccttttctgt caaataactg aactccaagt
    61081 tctttttcta aggaagatat agttttgctt aaagctggct gtgctatatt taacttgtgt
    61141 gatgcttttg ttatgtgctc cattctagca acagtttgaa aatacttaag atgcaataaa
    61201 tccatagtat aaaatacacc tcttttaata tgacttgagt tatatcaatt ttataatcaa
    61261 ctccacatta tacattataa tataaagttt atataatcaa ctacaatata ttaaaaagtt
    61321 atttaaattg ttatttatat tttgtacata atctaattaa aaaaagtagc tttaaatgat
    61381 taactaagga aatgttgtta caaactttag ttatataaaa aattcatttg atgagtaaag
    61441 tattaatgtc aagtaagaat aaaagcttat tagatagaaa aataatattt tataataatg
    61501 atgttactta aattattatg ttatactatt ttaaatagga aacatttaga tactataatt
    61561 ttagggggag tcaagatgaa attaactaaa tcaatatcat caatgctatg cttagctcta
    61621 gttttaagct tatcaccagt agcatatgca aatgaaataa gtagaacaac agtggagaat
    61681 actttagtag gtcaggacag ataccaaact gctgttgaag taagcaaaaa aggatggagt
    61741 agtgcgaatg aggctgtagt tgtaaatagt gaatctattg tagatgcatt agctgtaaca
    61801 ccatttgcta aattaaaaaa tgctcctata ttattgacag aaaaaaataa tctaaattca
    61861 caaactgaga aagaattaaa aagattagga gttaaaaaag tttatataat tggtctatct
    61921 agttctgtat caaatgatgt gcaaaaacag ttagaatcta ataatttaac tactgataga
    61981 gttggtggta gtgatagata ccaaacagct ttgagtatag ctaaaaaaat agaaggatta
    62041 aaagatatat cagaaatagc tgtagtaaat gggtacacag gtcttgcaga tgcagttagt
    62101 atagcttctg tagctgctac taatggaatg gttatacttc cagtatctga tgcatctggt
    62161 atatctagct ttaaagattt tatagaatct aagaatataa ataaatcata cataataggc
    62221 tctactaatg ctgtatcaga taaaataaaa caaagtttac ctaattcaga aagaataggt
    62281 ggagcagata gaaatgaaac taatggtaaa gtaatagaaa agttttatac atctaataaa
    62341 ttaaacaatg tatttgtggc taaggatgga atgaaaaatc aaaatcaact tatagacgct
    62401 ctagcagtag gagtactggc atcaaaagaa aattctcctg tactaatcgt aggagaacaa
    62461 ttaagtgcaa cacaaaagag tgtatttttg aataaaaatg ctacctctat aactcaagtt
    62521 ggtagtggag gaaatgaaaa tgcatttaaa gaattaaaag atttacaggc aaatagtaac
    62581 aataagagag taatgtatgt aactaataca gataaggtaa atataagaaa tgatgctaca
    62641 atagaagctt ctgttatagg atatctaaat aatggtgatg aagtagaagt tttagatgtg
    62701 ttaaaaactg gatgggtaaa aataaaatac aatgaaggta ttggatatgt tagtgggtct
    62761 tatttgacaa ataataagcc tgataatagt aatgaaaata taaaaataaa gtatgtaaaa
    62821 gaaaaagatg gtctaaatgt taggaaagga ccaagtacag aagatgaaaa aataggtcac
    62881 ctttcatatg gaagcaaagt agaaacaata gaaatatttg ctactggatg ggtaaaaata
    62941 aagtataatg gtggatatgg ttatgtaagt aatgattact tatctgatac accagttatt
    63001 taattataag taacaataaa aaactgcttt aatttgtaaa gcagtttttt tataaaaatt
    63061 taagtctaat aactatttct attttgatac cttaatcctg ggatttatta ttatggatat
    63121 tatcaacata caaacactcc aaatccagtg tctaattcca aacttagata ttaataaatt
    63181 cagtcctgct atggtaaata agcagtattt aattacaatt aaaagtgtat ttatagaaat
    63241 ccccttcata gaaagtatcc taaatccaat aatagacatt ctaagtccta taaatgccaa
    63301 taatatacct gcaatatcct gaattaagta atagtattca aatttcatat tcaatcaact
    63361 cttctctgag cagtatcaaa tatttctaac tcttcaattt catcatctgt gtatgtaagc
    63421 atagtaaaac cagttacacc ataaataaat gaaattatag gtgtaatcca acttaagaaa
    63481 caatatggaa taaattctag tgggcttaca ccaagagtct gagcacagaa aacagcattt
    63541 gaattccatg gtattaatgg accaccaagt gtagctgtat cttctataat tctagataga
    63601 ttttgtggtt ttaatttaaa ctctttgtat attggagaca ttagagttcc gacaaataca
    63661 gaagtaaaca tcattgatga actaaatgca tttgcaaagt agcttactat aaaagtagac
    63721 ccaaccaatt tagttcttga ttttcctatt ttagttataa gaggttgaag cagtacttct
    63781 aagaatccag ttttttggag aataccggca ataacgaaaa ctacaaatac tagtaaaacg
    63841 gtttcagcca tactcattat tccaccacga tttaatagtt tgtcggcata gacaaatcca
    63901 gtatctatag taaatcctga tagcatgtaa tttaaaatat cacctatttt ttctccttct
    63961 tgaaatactg ctataataag tcccatgata gctgaactta gtatagatat aatgggtggc
    64021 ttttgtagca ataaaagtaa taataaaaat attattggaa tcattgctac taaaccaata
    64081 tgaaagtttg aatttaatac atccttgatt tgatttattt gaacatagtc tatagtatta
    64141 tttgaatact taaatccaat tactgtatac agaactatac atattacgta tgcaggtcct
    64201 gtggtataaa acatatgctt catatgtgta attacatctg tcttacaaac tgctgcagct
    64261 aagtttgtag aatctgatag aggtgacatc ttatctccaa agaaagcacc agaaatgact
    64321 gcaccagctg ttaaaccaag aggaataccc atactagtac caatactcat cattgctata
    64381 ccagaagttc caagagtccc ccaagatgta ccagtagcaa cagaagttaa tgaacatacg
    64441 attaatgttg taagcagaaa atatttaggg gttattattg ttagtccact atatactact
    64501 gttggtattg taccagcagc tatccaagct gctattagta caccaacaga aagtataatt
    64561 aagtttgatt gaaaggcatc tttaccaact tcaaatccaa aagcttctat ttcatcatta
    64621 gtataaccaa gtttcgtggc tgcaggaact actataagcc atgaaagtaa aaacattgta
    64681 gttatagaag cattaaatac aactatacca actgatgtta gagctattat tgcaagcatt
    64741 actaacaagg aatatctaaa tgaaggtatt tttctttctg tattcatttt catagtgcaa
    64801 attctcctta aatattttta tttaattgca ttttttattc ttataagagc ttcttcaagc
    64861 atacttcttg gacaagctaa gtttattctt tgatacccac ttcctccaat gccaaagctg
    64921 tttccttgat ttagagcaac tttacctttt tgtacaagta cactttctag ttcctcatca
    64981 cttaatccaa gtgcactaaa gtctacccat aataaataag taccttctgg ttttctaact
    65041 ttaagttttg gcatattttc atttatatat tttatagcaa aatctatatt agattctaaa
    65101 tattctaaaa atgattctag ccaagattca ccattattat atgaagcttc agttgcaact
    65161 aagctaaagc aattatttct ctttatatca attctggtaa aagcatcatc taacaattta
    65221 tagtcttttt catcaggtag tattacatat gatgattgaa gaccagctat attaaaagtt
    65281 ttagttggag ccatacaagt aattgtattt ttttcaaatt ctttagaaat agatgccata
    65341 ggaatatgct tatgtttttt taatataatg tcactatgta tttcatcaga tatgattttt
    65401 acattatgct taagacaaat atctcctagt ttttttaatt catcttttgt ccatactcta
    65461 ccaactggat tatgaggatt acaaagtatg aataatttta catctttaat cttgttttca
    65521 atgtcttcat aatccattat atagtttcca ttttctagtt tctgtaatgg gcttataatt
    65581 agttctctat tgttattttt tacaacacta ttaaaagggc tgtaaactgg ttcttgtatc
    65641 attattttat catttgcttt tgtgagttca tttattaaaa gacttatagc tgggataaca
    65701 cctggactat aaattaacca ctcacttttt attttccagt tatgtctcct atctagccag
    65761 tttactatag attcattgta agaatctggt cttgttgtgt agccataaat ctcttgttct
    65821 agtctatttt ttaaggaatc aattatacaa ggtgcagcct taaaatccat gtcagccacc
    65881 cacataggaa gtaaatcatt agttccatac tttttttcca tttctgacca tttagatgaa
    65941 aaattattgc ttctatcaac aatctcatta aaattataat tcattgtaaa tacctccagt
    66001 aattttaatt ttatgttaat aatattaagc aaacaacgtg ccaatattga taataaaaaa
    66061 tatttattca caagttaata tttaatatta agtaatttca gagcatagat aagataaaaa
    66121 tattaattat acttaaaact ttgtggaaaa ggttatttct aataaatttt taaatatatg
    66181 aaaatgtaat taaataggtt aaataggttt aactgtttaa cttgttagac ctatttatat
    66241 tttttagaaa ttctactcct tttgatgtta taattgaacc tccacgacca acaagtatgt
    66301 ctacaagccc aaagtcttgt agttctaaaa gcatatttct aatctgttgt tctgtcaaaa
    66361 atctattttc ctctaaagct attttacata agctttttct acctattctt tcttttaaat
    66421 cataagcctt ttttaaatta tccaatataa atatgtattc atctagtgac cttttaaaat
    66481 tatagtcgta tttcatgatg tttttgtctt tgccaatgtt gaattgatac ttttttatat
    66541 tatcacttac tttattacaa acggttctac tataatttga atctatagtg tccaatatat
    66601 attcaggtaa atcacatatt tctataatat cttttcccaa gtaacagaag tattctccta
    66661 agtttcttaa ttctcttaca tttccttccc atctatacat tttaaagatt tcttttactt
    66721 cctcacttag aataaaatta catggaatat catattttaa tgaaccaaaa atttcaaata
    66781 tatcagcagc tctttcccta agtggatgta ttttaagggg aagaacattc aacctaaaat
    66841 ataaatctct tctaaacata tttttagata caagttcttt taaatttcta ttagtagctg
    66901 caattattct tacatcaata tcaatgacat tattagaacc aatacgtcgt acttgttttt
    66961 cttgtatgac tctaagtaat ttagattgag aatttaaatc catttctcca atttcgtcta
    67021 aaaatatagt tccattgttg gctaattcaa ataaaccaat tttcccacct tttttagcac
    67081 cagtaaaagc cccttcatca tagccaaata attcactttg cagtagattt tcttgaaaag
    67141 tactacaatt tactgcgaca aagggaccat cttttctcct agaagcacta tgaatggatt
    67201 gagcaaataa ttctttacca gtaccacttt caccaattat aaggatagat gaatttgatt
    67261 gagccatttt attagcaatt ttttttgtat taatagtttg tatactagaa cctaatatat
    67321 catcaaatgt gtatttactg atattaccag agtttactag ttgtgctctt aatttagctt
    67381 gctttttttc taattgagaa aactttgtca tctttagtat aaatccatca aatacattta
    67441 attgtatatg tttaatctct aaatttatat caatatgatt tattttaatc aatttctcaa
    67501 aaaatggagt tttattggtc aatatgtttt gaaaattgat gtcttttata caatcaccaa
    67561 caaatgagtc aatcatttca tttgcattta tagacaaaat ttttctagct atatgattat
    67621 agaattgaat tattccatca ttatttgtgc atataattcc atcatcaatt atagatagta
    67681 acaaatcaaa ttgtctttca aacttatttg catctaacaa taactcacct gtactataac
    67741 ttgtaggaat tattttttct acgtattttt ttattaggtc atcttttatt agatgtttta
    67801 atttggtttt tgtagcaatt tcaacaatac aacttaaatc tattattctg tattttaaat
    67861 ctacaacttc acaattttta aacttaggca ggattttttc gccaggagtt aggattacag
    67921 catctgtggg agtaaactca atctctggat agcagggcag gatatttata ttgtctattc
    67981 ctaatctatg tattaaagaa attgtttcta ttgccatatc tttacttaag ttatatacat
    68041 aaataatttt atctttttct aatttggata tcatatcaat actgttcttt tcaaatgtca
    68101 acttgggaac aatgatttga gcatcatagt gagataattt tactatttca tcgtatttta
    68161 aataagcaga taggagtata agtttttctt taaaaaactt taaatttccc tcttcaaatg
    68221 agtataaatt tatctttaga ttatcaccta agaattgcct tatttgattt tcataaattt
    68281 ctccagcgtc tttttttaaa cttacaatag ctaattccat ttgtttcatt ttaacctctc
    68341 atacaaattt gacttatttt agattacata ataattaaat tagattaaat aatattattt
    68401 aattattatt ataaatttat tatagactac acattgaagt aaaagaagta gctaaaatta
    68461 ttccttttat ttttgttttt tgtatctatt tggtataata gtattagagc gtataataat
    68521 ttaggcaaaa ttttttaagg aagactagag gagaatataa aatgaaaaaa tgtctttact
    68581 gtaataggga tataaagtca ccaaataata aattagctat aaaatatgat gacaatatga
    68641 atatatatcc atgtcgtgca gaatgtaagg aaaaaattga agaatatata gcaaaaaaac
    68701 ctacatataa gtttataaat atattagagg ttcttttagg tgtgggcgga atattctgct
    68761 ttttgagtaa atggactatt gcagcccaag ttgtacttgg aattgatgca ctggttatat
    68821 ttttattccc attggcagga tttaagatga atggaaagtt aagtatggaa caaactaaga
    68881 atcaaagtag gtctattgca atatcaattt tggcatttat agtaataata accgtattat
    68941 attttaaaca agttggtaag tagagcataa ttgtataaga catcattaga gtatgaggtg
    69001 agtttatgga agaaagaaaa ttagcaccaa acaatgagag ggaagctctc ataaaaagat
    69061 taaaaagaat agaaggtcaa gttaagggga tacaaaagat ggtggaacaa gaacgttatt
    69121 gtgttgatat attggttcaa atatctgcta taaggtctgc tataaataga gtaggcacaa
    69181 ttatcttaga gaatcatata aaaggatgtg tagcagaaag cattaaacat gatgatgctg
    69241 ataaaactga agagatgata aaagagctta tggatactat aaataaattt acaaaataag
    69301 gaggcggtta gttatgaatc aacaaggatt tattatggaa attgttgatg atagaactgc
    69361 aaagttaaaa atgcaaagac attcagcttg tgctgcttgt ggaaaatgtg ctactacaaa
    69421 ttcagcagag tcaaaagaaa tattagtaga agtagacaac acaattggtg caaaagttgg
    69481 tgaccatgta gaagtgagta tggataatat gaatgtatta aaagcagctg taatggctta
    69541 tataatacct cttatagcac ttcttgtagg aacaataggg acttattata tattgggggc
    69601 aattggaatg acaactggag ttgaagccat aagtggatta gttggaattt gtcttacaat
    69661 aatctgttat ttatacttaa agaagaatga caaaaaattt agagacagta gagaatttat
    69721 accagtaata acaagaatat taattgacct ttaagataat tataattaaa aaatagcaat
    69781 gtgcttttta aataaatact caatacgtat ttgtagagtt taagtacatt gctattttta
    69841 tatttttatt ttgattttct gtaaggaata aagttttttc tgattttcaa aagattcaat
    69901 gttcttacaa aagaagttac aactaataca ccaagtgcta ttgcagcact tagaaatagc
    69961 gcatctgtac cttttgacat agccaaagaa taatttttct gaatcaaaga caacattgta
    70021 ttatatagcc caattcctgg tattagagga agaatacctg gaattacgaa cacaatagct
    70081 ggttgcttta gttttcttgc taaagtctca ctacacgctg agaccaaagc agcagcaata
    70141 aaacctgcaa aaactgcatt tgtagtaaaa ttaaataaat aaacatatac aatccaacca
    70201 attccgccag ttactccagc tggaagaagt agatatagtg gagcattaaa gaaaacagca
    70261 aatccagcag ttgcaacacc tgaaaataaa aaatgcaaaa tcatagacat atcagtcatt
    70321 agaaaggacc tcctattcta taccatgtat caaggacaaa accaactcca gaagcaattg
    70381 caataataat catagcagca tcaaaagcac gagaaattcc tgatattaaa ttccctgata
    70441 ttaaatctct aatagctttt ataaaagcaa ctcctgggag tagtggcatt atagcgccga
    70501 ctataagcat tttagggtca tctaaaatgc ctatttcaac tagtagaact cctgaaagtg
    70561 caattaaaaa agaagatact aaacaggaaa atgcagatat tgcacttatc ttcatcgttt
    70621 tatcataagt aattgcagca aagattgcta ttataaacgt aagtataaaa tttaatacat
    70681 aattccctcc aagcaaacaa gcaaaacaag cagatgcaat tcctgtacaa gagtaaaata
    70741 accataaagg ataaggtttt acatcttgga tttcataaag acgtgcaatg gcattatcaa
    70801 tatcatactc tttgtcacta acaaattctc gagaaaaact gtttaataaa gaaatcttgt
    70861 ttaagtttat acctcttgat tgaatcgttt tcataaacga aaagccatca aatttctcat
    70921 ctgaaataat tattactgta ggagttgtaa aaatatttac atgataaaac cctcttgacc
    70981 tgcatattct aaggacactg tcttcaaccc tagatgtttc agctccattt tttatcatca
    71041 gttcccctac aaatagagct agttttagaa tatttttctt atattcaagt tcctcatttt
    71101 gattcataaa tacacctcca aattaaaaaa cgtaatattg aaattatatc aaatttttaa
    71161 gtaatattcc ttaatatcta tataaatata ttatcttttt tttgtttcaa aatagtcaca
    71221 tttaaattat atccaattaa aagaattaga caatattatt tattatattt taacttaaaa
    71281 ataaagaaag taactatgtt aaatatggaa aaatggcaaa acacttgact attaattggt
    71341 aaaggactat aataataaat tatcatattg ataaaaacga aaattatgaa atgtctgtaa
    71401 aaataaaatt taaataataa ctaggaggag taatatgttt gagaacttga aaaaagcgga
    71461 tcctgagatt tatgaaagta tgaaaagaga gttaaaaaga caacaaagaa atattgaatt
    71521 aatagcatct gaaaacatag tatcagttcc agtaatggaa actatgggaa gtcatcttac
    71581 aaataagtat gcagaaggtt actcaggcaa aagatattat ggtggatgtg aatacataga
    71641 tgaagttgaa actcttgcaa tagatagaat caaaaaaata tttggagcag aacatgctaa
    71701 tgttcaacct cactctggag caaatgcaaa tattggtgta tattttgcta tgttaaaacc
    71761 aggtgatgtt gttatgggaa tgaatttatc tcaaggtgga catttaactc atggtgctcc
    71821 agttaatatt tctggtcaat attataaatt ttatgaatat ggtatagata aagacagtgg
    71881 acttatagat tttgatgaag ttagaaagat agcacatgaa gtaaaaccta aaatgatagt
    71941 tgcaggagca agtgcatatc ctagagaaat agattttaaa aagtttagag agatagctga
    72001 tgaggttgga gcattgctta tggtagatat ggctcatata gcaggtcttg tggctgctgg
    72061 tattcaccaa aatccatgtg aagtggctga ttttgttaca acaacaactc acaaaacttt
    72121 aagaggacct cgtgggggtg ttattctttg taaagaaaaa tatgctaaag acatagacaa
    72181 agcaatattc cctggtattc aaggtggacc tcttgaacat ataattgctt ctaaggcagt
    72241 ttgctttaaa gaagctttaa gtgatgagtt taaagaatat caggtacaag ttgctaaaaa
    72301 tgcaaaagcc ttagctgaag aacttattaa aagagatttt aaattgattt ctggaggtac
    72361 agataatcat ttaatactat tagatttgat taataaaaat ataactggta aagcagcaga
    72421 aaagagattg gatgatgctt atataacagc taataaaaat acaattccat ttgatccaaa
    72481 tggtgctctt gttacaagtg gaataagact tggtactcca gctgtaacta ctagaggtat
    72541 gaaagaagaa gatatggcaa taatcgctga ggctatagac ctatgtttaa cttatgatga
    72601 agaatctaag gctagaacat tggttgttgg tttaactgaa aaatatcctt tatatgaaga
    72661 atataatatt atggattaat tataaagaac aactaaataa aatacattta aataattaca
    72721 atgattgtgt atgtatttga atatatttag atataaaaaa ggtgtctcaa aatgaacttt
    72781 ttagtttatg aggcactttt ttgtatggaa tcgaacatat ttgtgttatt taaataataa
    72841 aaaatatggt tatctctatt tttagatggt ctctttgtat tttttaatta aaactttaag
    72901 atttcttaag aattatacta ggtttttcta aagatttaaa gtctatactt ataagtatag
    72961 taatcatatg aaaagaaaag ctttaacgag gagggaatct tatgaaggta ttaattctta
    73021 caggaaaatt tggtatgggt cattactcag catcaaattc tttaagtgaa gatataaaag
    73081 caaaatttga taattcagaa ataacaatta aagatatatt tgaatacatt atgcctaact
    73141 attcagataa aatgtacaag actttttcta ttcttgtaaa tcggggaagt agtctttata
    73201 atttgtttta taaatgtgct gaaaatggaa agaaagatat aaaatttact ttttcagatt
    73261 attttttaaa taaattagat acattacttc atgaagtaca accaacagta gttatttcaa
    73321 cttttccatt ttgttctcaa ttagtatcaa gatataagga aaaatataac tcaaatcttc
    73381 ctttaataac atgcataact gatataagta gtcactcaga atggattagt aaaaatacag
    73441 actgttattt agtagctagt aaatctacta aggaagaact tgtttttaaa ggaatagatg
    73501 aatctaagat taaagttaat ggtattccag taaaaaaaga atttaaaaga atagaacatg
    73561 taaatcattc aactaaaaaa aatattctta taatgggtgg aggattagga ttactgccta
    73621 aatcagaaca attttacaaa gaattaaata gtttagaagg agtaaaaact actgtaataa
    73681 ctggtaataa taaaaaaatg tactataaac tatatggtag atatgaaaat atagaggtag
    73741 taggttacac caatgaagta tataaatata tgaaagattc tgaccttatt atttctaaac
    73801 caggtggaat aacactattt gaaacaattt attcagaact tccaatattg gcatttaatc
    73861 catttttaca acaagagata gataatgcta gttttatatt aaataatgaa attgggagaa
    73921 tacttggtaa aaataaaaaa tactatgtag atgagataaa agatttaatt tatgatgatg
    73981 ctactcttaa agaaatgagc agtaacatga aagaattaaa aaaacaattt gacaataata
    74041 ccttagagaa tattttattt tcacttgatg aacaaggagc gtgtagagaa tgtatgtagt
    74101 aggtttaatt atcgttgttg cattgatttt tttagtccat tcaattatac ctacatacta
    74161 taataaacta ttaaataaag aggtattaaa aaatatggct ggagaaaatg aaattgcact
    74221 tacatttgat gatggtccag ataagagata tacagaaaaa ttactagatg tgttaaaaga
    74281 aaatgatata caagctatgt tttttgtagt agcaaagaat gctgaaaaag agcctgaaat
    74341 tataaaaaga atgttgagag aaaatcatat agttggttta cattcattgg aacacagaaa
    74401 tgcatggctt tatagttata gttatgttaa aaaagatttt attgaaagta caaatataat
    74461 gaaaaattta ggtgtagatg taaactacta tcgtccacca tggggtcata ctaatatatt
    74521 ttcaaattca tttgttaaaa aatataatct aaaaatgact ttgtgggatg taatggcaga
    74581 agattgggag aaagatagta cagtagacat tattataaac aagttaatga gtagaacaaa
    74641 agaaaattct ataatttgtt tacatgatgc aggtgaaaat tcaggtggtg cagtaggtgc
    74701 acctgagcgt actattgaag ctttaaagat agctattcca aaacttaaag ccagtggttt
    74761 aaagttcgta acaccagaaa ggatgtagtt atgataagta aaactgaaaa gaaaaataaa
    74821 tgcctaggta gtgtagcttt tttagtttta ctaatgggca taacaggata ttttgttttt
    74881 agagggcagt cagttgaatc attgataaaa tcattaaaag gtgcaagccc tatgtttata
    74941 ctaattggat ttgcaatgat gtttatatat gttgcctgtg aaggtataaa tatatactta
    75001 ggtatgaaag ctttaaacca aaaaactact cttttaaaat gtatgggata tgcttttatt
    75061 ggattttatt ttagttctat tacgccttca gcatcaggtg gtcaaccagc acaagtttat
    75121 tatatgaaaa aagacgatat aaatatatca tattcttcac ttatactatt agtcattgtt
    75181 gttattcacc aagtagttat actggcatat agtggaataa tgttcattat ggaacgtgag
    75241 tttatattaa ataatgtaag tggtatgaac attttactaa tatatggtgt aataacaaat
    75301 gttgctcttg tcattggagt aattgcaatt atattttcaa aaaaacttgt aaacaatttt
    75361 ataatatcaa taacaaattt attaggtaag ttaagaataa taaaagatgt tgaaagttca
    75421 agaaaagtta taatatctca aattgaagag tatgttaaag gtgctcaata tataaagcag
    75481 aatccaaaac ttgtagtcca aattttagtc ataactattg tacaaataac agctatgttt
    75541 ttagttcctt tctttgtata caaagctttt catctatcaa catatactgt atttgagata
    75601 ttagcgatac aatccttgct taatattgct gtttcttcat taccattgcc aggggctgtt
    75661 ggagcttctg aaaatagttt tatgacatta tttaagatat ttttccctgg tcacttatta
    75721 gttccggcaa tgttacttag taggggaata agtttttatg catttgtagc tataagtgga
    75781 ttgatatgta tagtagtaca tgtaaaatct tctgaaaaag taaaagcagt gaaaaaagtt
    75841 gcttatgtaa gataatatta tatagattat ttttattaat atgtcaattt gtgtgtacat
    75901 tttaattaag ttttaaacat gtttacagga gtataaacta ttaaaacgtg tgacattgct
    75961 aagcttttgc taataaagta taatatttta tatagtttga aatatttaag aaatatagca
    76021 aaaaaaggag cttggtgatg aataaagaga ttccaaaaaa aattttagta gctgatgata
    76081 atcctgagat tagggaaatc gtagaaatac ttttaactgg tgaaggttat gaagttatta
    76141 tggcaacgaa tggagaagaa gctgtaaact tagtagatag tacgattgat ttgattattt
    76201 tggatgttgt aatgcctgta aaaacaggat ttgttgcatg taatgaaatt agagaaaaaa
    76261 cgacagcacc aatattattt ttaactgcaa aaactcaaga ctctgataaa gttattggat
    76321 tttcagcagg aggagatgac tatttatcaa agcctttttc atattctgaa ctaatttcaa
    76381 gggttaagtc gctacttaga cgttattata tataccaggg aaaggaaaag gaaagagagc
    76441 caaatatatt aaaaacaaaa gagttatgtg tcaatttaga tactcaagat gttacactaa
    76501 atggagaacc tgtgtttttg acaactatag aatatagtat attaattctt atgttgaaaa
    76561 atagaaaaaa agttttttcg tctgaaaatt tatatgaaac tatttgggat gagcagtatt
    76621 tttatacggc aaataataca ataatggttc atattagaaa tttaagaaaa aagttagaaa
    76681 aagaccaaaa aaatccacaa tatataaaaa ccgcatgggg aaaggggtat tatattgatt
    76741 aacaaaatta agccatctaa gttgggagtt atactattga tatatgtagt aatctcagct
    76801 gcagtggctt tcattttaaa tataccattt tactctgctg ttgaatctat agtaaaagat
    76861 gtatcagaag ggaaagtata ttttaaaaga gaagtaaatc aacttatgga taattttcaa
    76921 acttatgtga ataacaatgg tataagagca gatgatggag atgatatagc aaaatggaat
    76981 agtgataatt ggtttgtttc tatgaagata tataaaggaa ataaggtttt ttatgataca
    77041 ttatactatc ctaatgaagt acctgataag agtgaggaaa atgagtttta tagcagtccc
    77101 atggctagaa actatgagat acaattttct gatattaaag ctaatatagt tgtagtagct
    77161 ttatttagat ttagatttca aaattttata gaagcaattt ctattacatt tatggcactt
    77221 acatttatta taacattttt actgttgttt agtagaaaga taaagtacct aaggaaaata
    77281 gaaatgggta taaagatagt agagagtggc agtttaaagt atagaatccc agtaaaaggt
    77341 aatgatgaat tatcatcact tgcatctagt attaatgaga tgagtcatac attggagaat
    77401 caacttataa aagaaaggga gatgaagaat aaaaataaag atatagtaac ttcgatatca
    77461 catgatgtta gaactccatt aacatcagta atttgttatt tagatttgat caaagaccat
    77521 aaatacaata gtcctgagca attggaacaa tacataaaaa atgtaaggtc taaagcatat
    77581 caaataaaag atttaacaga tgaccttttt acgcattttg ttaattctgg agaggaagtt
    77641 tcaaaagggt atgaaaaaat aaatgctaat gaatttattt ttcaattact tttagatagt
    77701 tcatatacat tggaggagaa aggatttcat ataacaatag aaaatgaact ttataaccaa
    77761 tatcatattt atgtagatgt tacacaattt agaaggatat ttgataattt atgttctaat
    77821 ataataaaat atgctaggaa agataagcct atagtatttt taattaaagt agaggattct
    77881 aaattactaa ttatacaaaa aaatagagta agtaattttt ctaagaatgt agaaagtttt
    77941 ggaattggta taaagaattg tgagaaaata gttgcatatc ataatggaag cataaatgta
    78001 aattcagatg ataaagaatt tgctattgaa atatctattc cagcaaaaga atcataaaaa
    78061 tttaaattat atattgtgta attgctatta tatattgtgt aattgcttat gtaaaattct
    78121 atgaagcagg aagcatgtga ctttagttat gggatgttca atattgtgta cctctaggca
    78181 agtaacaagt ttacttacaa gaccatataa tattattatc ttaaaaaaag gggacataat
    78241 aatatggttt tgacaggagc acattatatt tacattctat ttatggtaat tatattaatt
    78301 actatgatta tgaaaaagga tacaatagta ccatgtatat taggtgtttt ttttatggga
    78361 ttgttctttg aaaaaaacat ctttggtgct ataacagcag tgtttaactc ttttattata
    78421 tctttaaatg agttgggtcc aattatcttg attatagcta ttatggttgc attatctaaa
    78481 gccctagaag ccaataatgc tatacagtat atggtgagac cattttcgag agttataaaa
    78541 aattctaata cagcattttt tgtaactgga tttgttatgt tagttctttc ttggtttttc
    78601 tggccaactc cagctgttgc cttagttgga gctgtatttt tacctgttgc tatgagagct
    78661 gggctaccag caattggtgt tgcagtagca ttaaatttat ttggtcatgg tcttgccttg
    78721 tctacagact ttgttattca aggagctcca agtataacag ctggtgcagc aggtgttgca
    78781 gtatcatatg ttataaatga tggtatgatt ttgttttggg tgatgggaat cgtaaccata
    78841 tctatggcat tttatacatt aaaaagagat attaacaaag gaatgtttag agaagaacta
    78901 aaaggttttg aaagtgaaga agtagaagag ttcaatggaa aatctaaaat agcaactatt
    78961 ttagtagctc tgggatttct tgctgatata attgttatgt atatatttga cctaaaagga
    79021 ggagatgcat cagctctttt gggtggaaca gcagtatttt taataataat tataaatgtt
    79081 ataaattttg gcaaagatag tcttgaaaat gtatgtgaga atataattga tggttttgtg
    79141 tttgggataa aaatatttgg agcaattata ccaatagcag catttttcta tatgggtgaa
    79201 gttgcgccct tgacaggtgt atttggaaaa gtattagcac caggttcaca aggtttatta
    79261 tcagatatag gcatagctct ttctcaaaca ataccactta ataaatttgc cgtatcaggt
    79321 atagaaactg tagtgggggc aataactggg cttgatggtt ctggattttc tgggatttca
    79381 ttagttggtt cacttgcctc tgtatttgga actgctataa atgcaagtgt tggtgcatta
    79441 gctgcattag gacaaatcag tggtatatgg gtaggtggag gctgtctagt tccttggggt
    79501 cttatttcag cagcggcaat ttgtggggtt agtccaatag agttggcaaa gcgaaacttt
    79561 gtcccagtta taaccggatt ggttgtaaca accatagtag caatgtttat tatttaataa
    79621 atcgaataaa tctttaattg tacaaattaa aaatagatgt gtagctataa tttattataa
    79681 ttgttttact aattttaagc catacatcta tttttattga tatttttatt agtattcttt
    79741 aataaaataa tatttttcat tatactatac ataacatcta aatataacat ctaaaatact
    79801 gttatctatg tttaatatct tgccaaattt tttgatgttt tattaccctg tcccaccaac
    79861 atatataagc tatcgcaagt tttttaccta tactatcacc aaacaaaaat tttaatttta
    79921 atttattatt ttataatcta tattatatta actatattag tttgtagact ttagatgtaa
    79981 ttctaaatat taatactcca agagttcaaa ttcatatcct agttttcttg catttgatat
    80041 aaaatcattt aaaatttctg tactagtttt ggaaactgca tgtagtaaca agatagaacc
    80101 atcatgtaga ttatccatta ttttttgcgt tgcttcttca tgtgatggtt gtttatcagt
    80161 atcccagtct ctgtatgcaa aactccaaaa tacagtcttg tatcctaaat ttttagtcat
    80221 tgccaagctt ttttctgagt attttcccat aggaggtcta aaaaatttaa ccatatcttt
    80281 cccagttaca tctttatata acttttcaac atcatataat tcgtcattaa agttttttag
    80341 attgcttgtt tttgttggca tagatggatg ggttttacta tgatttccaa ctatatgtcc
    80401 ctcagaaacc attcttttta ctaaatcttt attttctttt atatatggag ctgtaacaaa
    80461 aaaaactgct ttaacctggt tttgttttag agtgtcgagt atctttgtag tgtatccatt
    80521 ttcataacct tcatcaaatg taagatatag tgttttttga ccatcttttg taggtccatt
    80581 gtatagggca tcatagtcag aaaatttaaa ttcaatgtcc gtatttactt ctggtgtttt
    80641 atgcttattg ttaggtatat aaaaccaatc aagagtagtg ttatctaaag aagatacatc
    80701 taatttatta ttatcattat tagtagtggc ttttgatggt ttatctgttc cgtctgaaac
    80761 tattacattg gaagtatcct taccaccatc tattttttcc ttatcttctt gtaactgtgt
    80821 ttccttattt tgattttcgt tttgattgtt ttgtgaattt gaacatccaa caataaaaaa
    80881 aatagaaata gaaagtagtg ttaaataatg caatactttt ctaaacattt tgaagctcct
    80941 ttctaaatta ataataattg catatagtat tattataatt ggaaattact attaataata
    81001 gttatatctt taaaaataaa gtcacaatag tatgacaaag ggtgaataat caataaattt
    81061 aaaaaaaaat gaaaaaaata gttgaccata ttatgagaag atgttattat aataaatgtg
    81121 ctcaacaaga agtaacaaaa taacaagcac aaagaagtta attgaat
//
LOCUS       DAEQJM010000013        78061 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.013, whole genome shotgun sequence.
ACCESSION   DAEQJM010000013 DAEQJM010000000
VERSION     DAEQJM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 78061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78061
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.013"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            283..738
                     /gene="smpB"
                     /locus_tag="KRQ43_001129"
     CDS             283..738
                     /gene="smpB"
                     /locus_tag="KRQ43_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBH2741499.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            896..1245
                     /gene="ssrA"
                     /locus_tag="KRQ43_001130"
     tmRNA           896..1245
                     /gene="ssrA"
                     /locus_tag="KRQ43_001130"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1919..2824)
                     /locus_tag="KRQ43_001131"
     CDS             complement(1919..2824)
                     /locus_tag="KRQ43_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P63C domain-containing protein"
                     /protein_id="HBH2741500.1"
                     /translation="MESKEKSILRATHFGIIKIGEKDLNCAVLENGSRIINKSTVFKA
                     FGRTKRGRKKDEIRVPSKPNLPSFIDAKNLSDYISDELEDMLINTIKYKTKNGRIVEG
                     YPAEIIPLICDVYLQARLDNKLAVQQEGLAIASEILVRSLSKIGIVALVDEATGYQYD
                     RDRDELQKILSMYISKEFLPWTKRFPDEFYRQMFRLKNWTYPRPSSKRPGIVGTYTNK
                     YVYDLLPPGVKEELQRVNPTVKPGQRKHKHHQFLTEDIGNDHLKNHLLKVITLMQASK
                     DWKDFNVLFNRAFNLPVQLEIEYDE"
     gene            3735..3950
                     /locus_tag="KRQ43_001132"
     CDS             3735..3950
                     /locus_tag="KRQ43_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HBH2741501.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKSYIVEDLIQVLEEKGVM"
     gene            3950..4429
                     /locus_tag="KRQ43_001133"
     CDS             3950..4429
                     /locus_tag="KRQ43_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HBH2741502.1"
                     /translation="MIVYHDSYCVAKTPNIIFLRDSLDFGKGFYVTSIKTQAINWIER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFNSYNLEWLDFILECRNMSDVYMKYDVIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRCEEEV"
     gene            4435..4665
                     /locus_tag="KRQ43_001134"
     CDS             4435..4665
                     /locus_tag="KRQ43_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741503.1"
                     /translation="MEANKTLLQILYKKIILEFSNQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(4781..5947)
                     /locus_tag="KRQ43_001135"
     CDS             complement(4781..5947)
                     /locus_tag="KRQ43_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH2741504.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHMQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENRLEILTLEQQKNFIKAIEGHKLEVLFLVALGTGLRLGELLGLKW
                     FDIDFKNSNLTVKRTLQRTYFIDKNGNRELKVLEQEPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNVDILKAGELYRNDNYVFCNELGVPIDDKRPLRNLKSILSSLDIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(5937..6689)
                     /locus_tag="KRQ43_001136"
     CDS             complement(5937..6689)
                     /locus_tag="KRQ43_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH2741505.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYIIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNNLFISDISIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            complement(6781..7272)
                     /locus_tag="KRQ43_001137"
     CDS             complement(6781..7272)
                     /locus_tag="KRQ43_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741506.1"
                     /translation="MINNTIGEKIKQYRKSINMSRNELANKIGCSVHAIAKYEQNQRI
                     PSLDMIRKISTALSIAINKLIVEENDLDTLTNNNINLKVFDKELDLVVHILENYGYDI
                     KTDYKKKFEITDNADTIKPISLSFSDFKDFSKNLNWVINGLVENFIQENSNGLIEDED
                     EEY"
     gene            complement(7523..8287)
                     /locus_tag="KRQ43_001138"
     CDS             complement(7523..8287)
                     /locus_tag="KRQ43_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741507.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISGISRNALINYENDKRIPSI
                     DTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYFLQSLFPEEYYSFDEFLNAISNLME
                     DDDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCVSNTELDFSLHPDDI
                     KEIIKNDVLIKQSIDELLDIGLSEENIEAIYDYFSEATDNGSNIRLKKLISQKENMTI
                     KNNDYFKLLQENNELKEKNKKLENTLKEIKKLLTKI"
     gene            8434..8634
                     /locus_tag="KRQ43_001139"
     CDS             8434..8634
                     /locus_tag="KRQ43_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741508.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKEE"
     gene            8638..8952
                     /locus_tag="KRQ43_001140"
     CDS             8638..8952
                     /locus_tag="KRQ43_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741509.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            8974..9717
                     /locus_tag="KRQ43_001141"
     CDS             8974..9717
                     /locus_tag="KRQ43_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741510.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITLLLMASHKENHV
                     FIDNKRIKIKSGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSIIREYDKEAVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYHSKEIVINKETGIYNPDDSQLKW"
     gene            9730..11064
                     /locus_tag="KRQ43_001142"
     CDS             9730..11064
                     /locus_tag="KRQ43_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2741511.1"
                     /translation="MNNSNNLIKNTEAEQSILGSILLDSTIVEELEQMLNEDMFYHEE
                     HKYIFNAIKEINKRNEVIDIITLTEELKRKGHLNNIGGISYITSLSTIVPTVSNFTSY
                     VSIVIEKYKNRNIIDKFNKFNLGEIDDNTLIYQLENDINKANQKLIKKDSSITAISER
                     AFEYINDEMNEGIKTGIKFLDDTIGGLYGGELTTIAAKSGRGKTALALQILRNVIFQG
                     KKVLFISGEMSDIQILFRNIASLTGISVVKMKNRNLNDDEIVKYIQALSIINQENNLY
                     INDSVNTVSGIKREIKSTKPSLVIIDYLQILDYEGKEVGEAKFADLSRQIKKITLDFN
                     IPVIQLAQLNDELKDERPKGDRVMRSSKQIYMDSNSVIYIHRPTEKEALNYCKTMGIE
                     DIRELRRREKGFGANLSEIIVAKNRDGESGFRPYWYIGNLFSFEECKKIQEI"
     gene            11314..11586
                     /locus_tag="KRQ43_001143"
     CDS             11314..11586
                     /locus_tag="KRQ43_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741512.1"
                     /translation="MYDEIIEIYFDYWINEHMYRSILEKDEYYIECWKEVKKINELLE
                     INLEDDKKYLLVELNDLFNSLIEFERELSYKLGFKTGAKFIIELLK"
     gene            11859..12986
                     /locus_tag="KRQ43_001144"
     CDS             11859..12986
                     /locus_tag="KRQ43_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBH2741513.1"
                     /translation="MIIPKLEPNDRKREFNKYSSEQINKVVYNYLFKNNMSNRKIDDE
                     ILDLSSKQSKGYQSMGIVHHLGINKNHKGIFTGYTIDKAIEVLKEDEIHFKQIINILL
                     EIRNINEYPIIVDSWELLDEKIALKTIDKSTLKHNGTGVPIEIRYFFEINNLGKNEKK
                     NVNFKYNDNYYSAVIEMDKLENPRSRIIWKSKFRDLLRSIFSEYYEKFLENKIEGKTN
                     LPKIRFIKLDSNNFNIEFIFTAEIEDDVLEEISQDNPLNINTINIELETEIRKEGKVK
                     YVYGKQYERNPRNRIEAIKYHGTKCIVCGFDFEKTYGDRGKGYIEIHHIKPLSSVGEE
                     SNINPKTDLVPICSNCHRMIHRKKDNVLSIDDLKQIIKDSK"
     gene            13466..14113
                     /gene="cas5"
                     /locus_tag="KRQ43_001145"
     CDS             13466..14113
                     /gene="cas5"
                     /locus_tag="KRQ43_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBH2741514.1"
                     /translation="MILNKIEIIGDMAHFKIPMHSKIQRTYEIPPISTVVGILKNIYG
                     EEIDDFILGYVIYHDGTFKDLQTIYKEINPNVKTLTDSDRFQTDVCPIEYLINPKLII
                     YTNIDKNIEFNEPLCLGKTNCLAKVLSLSEIEVNLIDKKAIGYNQYTDINIGDGMIKR
                     INTLTEYNEKKGYYDIYSSMVRENDEFEYGKYYDEDEQQNIFLWKWKKGGVIKCI"
     gene            14104..14868
                     /gene="cas6"
                     /locus_tag="KRQ43_001146"
     CDS             14104..14868
                     /gene="cas6"
                     /locus_tag="KRQ43_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH2741515.1"
                     /translation="MHLVRRHLILTVDNEVVLDYNYQYELMKRIYEAIEINDKRKALS
                     LHNEGYKVDKKVFKLFNYTIMFENAKYLKEGIHLNPQTKIKLILSGYDDILNNIIKGF
                     IKCKVFKLNNIEFKVSDIEEDSKKNFNNITLYKVRSPIVASLYDLKSRKQVYLNPMQE
                     EFYKALHDNLGNKYKLIHNKEYTGELYFDIEDVLAVKKKYITNIKGKGFIIGYTDFEI
                     FVQANKDMQEVIYYCGLGEKNSIGMGLLTYITSRRA"
     gene            14870..16036
                     /locus_tag="KRQ43_001147"
     CDS             14870..16036
                     /locus_tag="KRQ43_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741516.1"
                     /translation="MDRSYNVFVDNGLYVLAYYLNKDINDITYQDIENSIDLMSDKIE
                     EFVSCEKYSNLKSMCFSNSTLTQPKGKVTLNEKLKGFVKNQGDEYCSLCGQYKAKVKI
                     EDKEYNIGRSYMPNLVANTFYNFSNNLQGLNVCPYCLVLTMYSILNCRVSRYAFLYNS
                     TSSEFMEDYTFHIQKENLTDVELGAKKEKEKYSIVKLLESLVCKYNLFNGDIEQYMFN
                     NSGQSQDIQVNRIKNKYVNLLIKLQEKALLSNFEKLHLDRYILNGTLESNYLREVYRV
                     KKEEKMDEKEQKNFDELVIFLNREVNVLKKVKIDIIKKLTDKLKTSDLDIDKIYKELK
                     MLGKFYAYEDWLVNLNEMYYEKTGEKLFEAEDYIELDDIRSFRQIKNLILVSLI"
     gene            16057..17127
                     /locus_tag="KRQ43_001148"
     CDS             16057..17127
                     /locus_tag="KRQ43_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
                     /protein_id="HBH2741517.1"
                     /translation="MENKNSNRMLNIGYAIEVLCGRLNGSSSEVEKKNNSYKNSTYTK
                     KIGSRSRISSQCQKYNQKLFMEQVCGYEQNVKTKDGKQVKLVPNPFKYATDDIFGFMM
                     AEKLSIEEDVYKELSDEEKEIYKKNKKKYEVNITKKRKSRWQMNSLINVSNRKVEWEW
                     NVCGTTGDSMPYQVEVYSGVHTNIANLNIGKIGEYDISDIASEHRDYTTLEAKSIGVE
                     KLDKEEKFKRIEALLKSLEYLSVEGNKTNHLTDTKPKFVILGEYSWGNNVFQGIIKEN
                     GLDVEMLKESIEQNEEFRKSDIWIGINKFYDDTFNEIEVNNEKEQIKKYLEEEFEEYD
                     FMKISNVHQAFESYLKYLKETL"
     gene            17138..19123
                     /locus_tag="KRQ43_001149"
     CDS             17138..19123
                     /locus_tag="KRQ43_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH2741518.1"
                     /translation="MNNLYEYKAKSDGTSIDKHNEDMNYIMNQLVSIYNISNDMKNDL
                     YEAIVCHDVGKVVKSFQDNIESSTRRVRHELLSASIKYLNRGQKLAILTHHKDIKFLE
                     GQITNSIYEIELKELKELLDIEVEDIRPFIKEISRARNDDTRKLENILLKGYLQYCDH
                     IASAGIKSIDKGFNSIKDFSIPKGVSYNSIQEKVLNMDKNEDIMIMAMTGLGKTATSL
                     YWSNLVQNEYKSKRVYYILPYTASINSLYENLYNRNISVSMLHSKAPYFLNKISDEED
                     IKQLYQIYKKSVKQINVCTIFQLVKSVFSCKRFEMLLSQLKDSIFIVDEIHCFDTRVL
                     CYTLEFLKYLKENLNVKICIMSASIPTCLKKLIQERLQISTIIEPDSKDLIFRHRLNR
                     LSEGILDSIHKIENDLMQGKRVLICVNSVDLSQELYGRLQKYNPKLIHGRFNTRDREQ
                     AEKGIEESFLLIGTQSIEVSLDISYDVLYTELAPLDSLLQRFGRVNRRGDNAELSNIY
                     IYDYDRKLNIYDEDIINRTDIVISDIIHNDNSIVDESKVPSYLDNVYLDIDMDKYNKH
                     KVALEIIMKNMRLGVWNKSANNDMLNNDTISVVPECLLEEYKLYIDKKMYLEASSLFV
                     NVSVKRYNYNKKMFYECGDIVVTSYSYNDKLGLIFDC"
     repeat_region   19376..19998
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=19376..19404
                     /rpt_unit_seq="gtttaaattacactaagttagttataaat"
     gene            20443..21999
                     /locus_tag="KRQ43_001150"
                     /pseudo
     CDS             20443..21999
                     /locus_tag="KRQ43_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003444896.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            23177..24391
                     /locus_tag="KRQ43_001151"
     CDS             23177..24391
                     /locus_tag="KRQ43_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FRG domain-containing protein"
                     /protein_id="HBH2741519.1"
                     /translation="MGEKMQSVICKIFDNKLLISNDLSEQDDVLYEVMDKFIDDIEYI
                     SKLGDEQIKSMLMEVNKFEEDSTEFELYMKNLCYLKQSYFIDTNDKSEINSIDIDILK
                     NVKIEDLVDITNIKLERNLNINIEHISKAVNKIYEENEKWKEYNIQNTMSKYIGIPES
                     EVIFISNLSQYVSFLSELDNAGDYVSRGQKDCMYELLPSLHRKYKKDYGIHSDEYEEA
                     FKQKIIYYDKEIKNRSSEELRAEGQHFGLPTEYLDFTEAHLISLLFAIEDYKYTKQHS
                     IVYFIDSISYNTDTIKRSEKLVNYSDTSAIDNCSKFSSRSFFIKVGNSNERIHFQKGC
                     FLKVSSEDKGEFKEKLKKYCKVVVINKDAKKEILKELFNLGITFENIYPDKDNVVKSI
                     KFYYDEIVGGNL"
     gene            24391..25683
                     /locus_tag="KRQ43_001152"
     CDS             24391..25683
                     /locus_tag="KRQ43_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HBH2741520.1"
                     /translation="MREQFKNSIKNIKSNRPLVSVQDIVNFIDKGEKYLKLSIDEIDE
                     MEILQGIVMSPDYQRTYKSSNKEESSIIESLLIGIPIPEIFLVKIGVNDMQIRHVMDG
                     QHRLNAIYRYVKNKYPLKNLDILGNDPLYDNKRFSELEKKDKIKILGSHLSILEFDGF
                     DNPEIEIELFKRYNRNTKPLEMQEIEMATYFSETSKYISKFINTLIKDKYKDEIDKSE
                     YKYANYKSDLLRIYNITKSRNDKQKNHQEICIIFSILENGLQENIRDGVTASKKFLEY
                     KSIQYKNNESEKLELLKDKFDEFNRMILKISEKIEYPFSTSLISDDKQRQSKYLIGVS
                     IVLASICYYYDIDLENNYLIQDIKKIISCSPIADIEYKASSTNMKNMILYLFIKNKIQ
                     DNKFESLNLKRDKIKEINTLVMNNDGYLNEQTRLLEIY"
     gene            complement(25910..26068)
                     /locus_tag="KRQ43_001153"
     CDS             complement(25910..26068)
                     /locus_tag="KRQ43_001153"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH2741521.1"
                     /translation="MEMYYLRKLDTYEQLVKTIEDYIYYYNNFRYQKRLNSMSPLEFR
                     KYLNTEIA"
     gene            complement(26125..26514)
                     /locus_tag="KRQ43_001154"
     CDS             complement(26125..26514)
                     /locus_tag="KRQ43_001154"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBH2741522.1"
                     /translation="MRAVGLSSVCRKKKFSYVKCTPEVIAENVLSRKFSADKTSQKWL
                     TGVTEFKLTNGMKAYLSAILDLDDRSIVSYVIGKSNNNNLVLETFDKAIELYPNAKPI
                     FHNDKSFQYTSKVFKSKLLTQGMIQSM"
     gene            complement(26526..26986)
                     /locus_tag="KRQ43_001155"
                     /pseudo
     CDS             complement(26526..26986)
                     /locus_tag="KRQ43_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888992.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            27415..28425
                     /locus_tag="KRQ43_001156"
     CDS             27415..28425
                     /locus_tag="KRQ43_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741523.1"
                     /translation="MITKIKKTYIYLKEIQKIYKINEHKELVHIIKKLINDNKIKPIK
                     TSDLTPQHEQLYTKYRIIKQETEEDKKILEEINYKICDKLSIDYYRKNLVHYKNNRVA
                     IMDLNSYLIKKSDNLSKKISINERSYEIFKDEKFISSKVGKEVLKNLKIDLIKDLNVY
                     KTPEPFIYLSINRISPQKILIIENKDTYITITKMLLEGKEILKNKIDTVIYGEGKKII
                     NSIKGLKEDITIEYLTNKENEFLYWGDIDKTGLSIYTSLKDTNEINNIRLFEVAYEHM
                     IDKTKENTLRNIPKNQKDNFECGLENINNLNLKESIKNILVQGKYIPQEALNRFDLEE
                     YN"
     gene            28425..30044
                     /locus_tag="KRQ43_001157"
     CDS             28425..30044
                     /locus_tag="KRQ43_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741524.1"
                     /translation="MEMINILEGYNKRVNCIGSYYLIATLANNRNKFKEFDNIQFYNL
                     LIQVLCYIFDRSLRRKNCLRDDIKDFIEEINRMDYKIMLSEDDLKDLANYIINGLTNS
                     GKVYLFTYYSLEQEKHIDESIKIIEDKNVKINNQERLSYSLTTEGYRLLLSTKEYDEL
                     FQIQISQMIAKLRIEKGDYQGAKEDIYDIINTLEIHQQKIDNYIKIIKVNILYIKEEK
                     YSTVIDTTVETLLEEMDKYEELKKEVKLLIKDKEDYLEKDEDIDKEKIKNIRTQLLQM
                     KELIDGIVLAKSTATNLLSRVQDFREEFKEILKKLLTTPVIKRFNFKEEILDRLEKDS
                     DFLLIIRELYISLFKVELPNRFNIGVAYQEQKLLNTREIENEIVNKDELEIIENKEKE
                     ERINYCENYYFDFFKYLIKYGLEKGQFTLEEFLKNYLKYDKVIYLEITKDSKLMRDII
                     IYFANQRESINIKKIIRMLENSAFSPNTDFQIERLIERLLVEDFELLNSVSHIKSNKI
                     FEDEMKINTEINLETMTAVKLEIANIKFEII"
     gene            30062..30790
                     /locus_tag="KRQ43_001158"
     CDS             30062..30790
                     /locus_tag="KRQ43_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741525.1"
                     /translation="MNISLNDYKIANEIFYRLLKKSELKEKEAKELFLAYINNSNVRY
                     ALEAICEVSKIKIILISDTLYLIPNNDNDIFGFDYRRESLLGKDLKDSYLGYLIMTII
                     FSEFTNGVAPASYIQVLNLLDLVQESLERSIARDNLEEIEKSCEFNITILKNYWESKR
                     KWDESSKKGIETTSADFQIGFIRKIINFLKNEGLIVHIEDEDKIKPTRRFLDLMNNYF
                     LDEERKVLIEKLVLRKGESINASN"
     gene            30777..35132
                     /locus_tag="KRQ43_001159"
     CDS             30777..35132
                     /locus_tag="KRQ43_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741526.1"
                     /translation="MPVINKYKIINFKFGMGQERILSNRTMELYGENLQVEAENTAGK
                     TMSIQTIIQSICPLSDVAKPFTAIYNKKEPLYSMTEWLLDDGKTLLLTGIGFEKKAGS
                     SKEEGKEKKDDLYKYFMFIIEESKEMEVDIDNIPLLKNNDKGIRIVQPLTASQDYIKM
                     LRDKYGKNKVHFFNNYLRKQHREKLEEYGINQSEWKEIIIKLNSNNKEGGLSDFVKEH
                     NTSEKLIRDKILPLIETSLTTEEFAPILQIKEQVRKCINNIIDMNEKLSDYKNYRDLN
                     IRVESLQNKINRILFIEEDKNNVLGELANLYVHIENKRNELNEEIKQYQKMKASKEEE
                     FKIVEYEEDSYEYFRKEKEIQDTQVEFDKAKNELNDKIEELELDEQYLNISKFKRKKK
                     GLEEGEKDKIEKESEKQRKEVNQEEITAIINRLGSSIHYCLKEESIINNEKLKENTNN
                     NIAIQEKKNQLNDDKSKLTKVLISKNSEIKYIEGKERDFNNQLHEFKLNNTDIKGFIS
                     NNFLGEVIDYTRYINYLNIKVKSIEENLESKVMQIEESNKLKDDINEAINNLKLDNHE
                     SYMKLQVLKTRKKDIDNFKEKYKIIKTRFEIDNELDNSTKLYKEVKQELNKMKLQVQD
                     LENNKKQLEKELEDLQNYKDIIFEEEILTDLERNGIKPIEGMKYLLTLDGDLEYKNNL
                     ISKNPLLPYSIIITNKEYQKLKQINLKNKTKISMPIFVRDNIEDTFITTSSNLVISNG
                     LNILSSFDNKALDPEKREKDMNLIKEQINSIRDKVEQYKAEIEILEEFKLLTNKIDFT
                     AEDLSIDVKIENYKKIIFEINNKIKSNENNEKNLSNKIKELYENKEKLLNNKNILFNK
                     LKDIRNIQDTYSIILENKNEITKLKTSIEKIEEEKKVIKKSIEDIDVNIFNLNSEKDR
                     INRHIDDTESKINKFKIYEPIKLENAKLEELEIKYKKYLEDPTKKEIETLNYEISVCL
                     KRIESITIELEEFRQLISSDNFENIPILFTIEELNKRIVLNKSKVDELRKLKYSIKSD
                     IDKNQGSLNTKREEILKKFNGKEPLSTSLIVNFNFEERKIDIKKDIKDIGEIIEGNRT
                     TCQNLEQELRDLKKYKVERKAITYQPEDIFIESKKLQSKLQNVEYNLIKSINSYKNTI
                     LEIKEFNYKHMEKYKNFIETLNVNKDNYSRQKEQVEIVLLVIREEISKLEKHSEQLRK
                     EKTIISRQIKDYVMDCIDEFKIINKLGKHKGQALFNISLPKSDKIENSLSLVDMLMDE
                     IVEEANLGDVEQKINTFYILNKTLNIGRIPVSVIKYEINRNETIKWNSINNETTGGQR
                     FCISFIVTILLMEYKRYDRNAIVDESKYKGKVLLMDNPFGETSQQDFLKEIFELAKKF
                     NVQIISYTHVTNASIRAMFNKIYLMTVEKTTSNKEFVDINEIKQNKTDELVYMSKFYI
                     GNKEELIQEDIFSLI"
     gene            35234..35443
                     /locus_tag="KRQ43_001160"
     CDS             35234..35443
                     /locus_tag="KRQ43_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741527.1"
                     /translation="MKNFVIVSTKAALLRVIIVRLLLKIGLKTYKYLSYFMKKEKLKR
                     IIRPEGCELRVNRSIQVERAIAEQI"
     gene            35839..35979
                     /locus_tag="KRQ43_001161"
     CDS             35839..35979
                     /locus_tag="KRQ43_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2741528.1"
                     /translation="MKIKIKKYREKLLMIQNELAKSVGVRRETIVHLENGLMYHKGIQ
                     DK"
     gene            36117..37079
                     /locus_tag="KRQ43_001162"
     CDS             36117..37079
                     /locus_tag="KRQ43_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH2741529.1"
                     /translation="MAKIDNMMSILWMLNSDKKVTAKQISEKLEINIRTVYRHIDALS
                     ASGVPIISDTGHNGGYTLLNNFIKAPLFFDTEEQTALLHAAIFAKEEGSFLDDTLDKA
                     TSKLKMYSNQKQEETLTKHLIGFEVIKPTGKISIESVLKKLKNSIANELSVEINYRTA
                     HEEKSKCRIINPYGIVRWNNNWYIVAFCQMRNEIRSFRVDRISSVIETSNTFNRPKEF
                     SASEFFIRGIMDETKDEDNLISLVIEGKMNALDNLCQHWLLGYYLKERTSNKAIFKLQ
                     EEIIFTYVPNILIPYRKSIQIIEPLSLRDKMVEDLLELINHYQI"
     gene            37157..37786
                     /locus_tag="KRQ43_001163"
     CDS             37157..37786
                     /locus_tag="KRQ43_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBH2741530.1"
                     /translation="MKKRKVYMYVFDTMSDWEVGYLTAELNTGRYFKKGLKPLKVITV
                     GVDKNPIITMGGLKVLPEITIDELNIESNDLLILPGGNTWTSIGHEKILEKSKEALEQ
                     RSIVAAICGATLGLAKTGLLDFRNHTSNDLEFLKMVILSYSGEKYYKMESAVNDENLI
                     TASGIAPLEFTVQVLKVLDVFKEEALSSWLNLYKTHDSKYFFELMNCNK"
     gene            38617..39033
                     /locus_tag="KRQ43_001164"
     CDS             38617..39033
                     /locus_tag="KRQ43_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741531.1"
                     /translation="MSKSETGVKSKLILELLVITYLFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSKFILSKVNQIAITIMMYSIVIIAIFFATPYISNI
                     NISNLDTGIILIAVLFIQSLSKLILYIYFDKRGICN"
     gene            39034..39246
                     /locus_tag="KRQ43_001165"
     CDS             39034..39246
                     /locus_tag="KRQ43_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741532.1"
                     /translation="MAISMKTKIKEYREKLLMTQNELAKSVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFGTTVENLFEFIEED"
     gene            39881..40924
                     /locus_tag="KRQ43_001166"
     CDS             39881..40924
                     /locus_tag="KRQ43_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBH2741533.1"
                     /translation="MKRKIAVVLLTVAMLLSLVACSNDNTSKSDKLEDTLVVYTTHGE
                     DMLGAISEEFTKETGVNVEFINLKGELADRVRSEKDNPQADIMFGGDTSTYMQLKEEG
                     LYEKTEPSWNNELDKSYKDSDGYWYGTIKTPVMMFYNTKLLSADKAPKDWSDLTKEEY
                     KDLIVTRDSLSSSMRSTISNLINYYSNTKSEEEAWKYLEDLNKNIKNYYNSGSVMYSA
                     IGKGEATISVAVLSDIIENKEKNNMPLEVVDAESGSVVITDCVAALKNAPHPNAAAKF
                     VDFVGSAKVQAMVANDFNRIPTLDSALKDSPKWMSKEYKAMDVDWSVIGKNQSNWIEK
                     WETDIIDNNKTIK"
     gene            41185..42059
                     /locus_tag="KRQ43_001167"
                     /pseudo
     CDS             41185..42059
                     /locus_tag="KRQ43_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421888.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            42078..43070
                     /locus_tag="KRQ43_001168"
     CDS             42078..43070
                     /locus_tag="KRQ43_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741534.1"
                     /translation="MKNIELKEINHYYGKEKVLHDINISIKEGEFFTLLGPSGCGKTT
                     ILRIIGGFIKPSSGSIYVGDKNITNLEPENRNMGTVFQNYALFPNMTVEENVSYGLKI
                     KKLSKKIIKEKCDNYLELSGMKDFRKKKIDELSGGQQQRVAVARSLATEPTMLLLDEP
                     MSNLDIALRIKMREEIREIQQKTGITTLFITHDQQEALAISDRIAVMDKGKVLQIGVP
                     IEVYKSPLNDFVANFVGTSNCIGKEDYVNFNIEKETKPYIYKRPEEMILLQNTNQSGF
                     VKVKVESKNFLGAILEYTVSNDGKKYQVTELNRLNNSNKLNVGDMAYLGVLQGD"
     gene            43072..44766
                     /locus_tag="KRQ43_001169"
     CDS             43072..44766
                     /locus_tag="KRQ43_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH2741535.1"
                     /translation="MIKKINRSKFTSKNVIFIVLYSILFWILIGYIIIPIGNTFVQAF
                     QGKGGYSFEVFKEYFSNTNNLRVVSNTIILGLGSVFVCGIMGISLALYMTFVCDKHKK
                     IIHILLLSPMMIPGVIMVIACIQIYGESGIVTKSIEILLPFIKKPYDFSGLKGILFVV
                     AYTQYVYFYLNVYVALKYVDYSTVEAAKGMGASKLRVFFDVIWPVITPAVITSTIITF
                     ASGISSFSAPNLIGGGFKVLSTQIVRSKANNHMDIASVQVITLLLMGILFMILLQYYG
                     KKYGVVPSLKSQSYKVHNRKKDLFTFVCKVIIEIQIIMIMLPIVTIVYLSFVSTHSIM
                     TTIFPRDFTLENYQMIFQKSRVLQPILNSFKMSLMAVAVGLIITVPVSYLVIKKDTAY
                     NRLAKFIIMLPWSMPASAIAVNLINTFNQKSIFAFNESLIGGFYIVPIAYTIYALPLL
                     FSSNEVAMKSINLGLEESSRSLGAGRIKTFYNVIVPNMMPGIISGAILVFIRTIGEYT
                     MSALLYGVYNRPISISIVTNMQEFKIGVSMAYGVLVIGICYIALGIIFKLDRKRFT"
     gene            45317..46195
                     /locus_tag="KRQ43_001170"
     CDS             45317..46195
                     /locus_tag="KRQ43_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBH2741536.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQGANEKNAPV
                     ILAIHPNELSFLGDSFVVSCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            46231..48126
                     /locus_tag="KRQ43_001171"
     CDS             46231..48126
                     /locus_tag="KRQ43_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2741537.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSETKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFPPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVAKPTIRSENS
                     EVELLGA"
     gene            48394..50301
                     /locus_tag="KRQ43_001172"
     CDS             48394..50301
                     /locus_tag="KRQ43_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH2741538.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDILSESEKVSSIMIENMSQFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            50291..50740
                     /locus_tag="KRQ43_001173"
     CDS             50291..50740
                     /locus_tag="KRQ43_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2741539.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNISERLLNVHTKKEILDIFYEV"
     gene            50840..51727
                     /locus_tag="KRQ43_001174"
     CDS             50840..51727
                     /locus_tag="KRQ43_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH2741540.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGGASK"
     gene            52132..53580
                     /locus_tag="KRQ43_001175"
     CDS             52132..53580
                     /locus_tag="KRQ43_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH2741541.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIIHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            53606..55996
                     /locus_tag="KRQ43_001176"
     CDS             53606..55996
                     /locus_tag="KRQ43_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH2741542.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHTRILDLNEGIVKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIELKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKDWI
                     NAAQNIYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLNYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKKDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGKNISILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            55998..56669
                     /gene="pgmB"
                     /locus_tag="KRQ43_001177"
     CDS             55998..56669
                     /gene="pgmB"
                     /locus_tag="KRQ43_001177"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH2741543.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLERGKPYPDIFIEGSKMLNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            56708..58108
                     /locus_tag="KRQ43_001178"
     CDS             56708..58108
                     /locus_tag="KRQ43_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH2741544.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNENKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIEKFINKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVKESTDNVVEEV"
     gene            58425..59267
                     /locus_tag="KRQ43_001179"
     CDS             58425..59267
                     /locus_tag="KRQ43_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH2741545.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            59412..61340
                     /locus_tag="KRQ43_001180"
     CDS             59412..61340
                     /locus_tag="KRQ43_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH2741546.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKFVPDLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMTIPNFISGIFGVTEPAIYGVLLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVASPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            61401..62828
                     /gene="ascB"
                     /locus_tag="KRQ43_001181"
     CDS             61401..62828
                     /gene="ascB"
                     /locus_tag="KRQ43_001181"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH2741547.1"
                     /translation="MSFKDDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYRGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLVGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     INYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            63239..64015
                     /locus_tag="KRQ43_001182"
     CDS             63239..64015
                     /locus_tag="KRQ43_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH2741548.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IVKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            64031..64396
                     /locus_tag="KRQ43_001183"
     CDS             64031..64396
                     /locus_tag="KRQ43_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH2741549.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(64562..65311)
                     /locus_tag="KRQ43_001184"
     CDS             complement(64562..65311)
                     /locus_tag="KRQ43_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH2741550.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     GKPFIFVCPTYAWRLPIVVTDFIKETKFLGDNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNS
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(65756..66313)
                     /locus_tag="KRQ43_001185"
     CDS             complement(65756..66313)
                     /locus_tag="KRQ43_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH2741551.1"
                     /translation="MRTLKYAILGLLNRNPMTGYDIVKEFNFQLAEFWNAKHSQIYPE
                     LKKLVNEKLIVYDIKISGDVLEKKLYTITEKGKDEFLKWLEKDEPMERTPKDIFRLRM
                     YFSNNLDIDTRLILLEHQLLQHQERITFLYSQMERYSEVPPLDSNDFGDYIVLDGAII
                     REQGAIKWLTNCINHHKNLDNTTLK"
     gene            66565..67863
                     /locus_tag="KRQ43_001186"
     CDS             66565..67863
                     /locus_tag="KRQ43_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HBH2741552.1"
                     /translation="MNLTQKRWIILIASCFINLCIGSIYAWSVFASPMAEHLNSLAGT
                     TFTAASLAIVFTVTNSVGPITMITGGMINDKFGPKKVVFVGGLIFGIGMILAGFSKGL
                     PMLILSYGIITGLGVGMVYGCTISNSIKFFPDKSGLVGGITTAAYGFSSVIMPPVANW
                     IINKYGVTSAFKSIGLVFLIIVCVSSFFIKKCPADFTPEGWVPPEKKGKVRVVINKNW
                     KEMLSTPIFYLMIIILTCGAFYGLMCVSLASSLATNMIGMTSSDSAIVVSILALFNTL
                     GRIVAGYISDKIGRINTLSGALVISIFGLLCLLFSREGDVATFYIGIIIIGICFGSFM
                     GIFPGFTVDKFGPKNNSVNYGIMFIGFAFAGYIGPAVMKNVYSVDGNYQRAFIIAIII
                     ALIGFILTFLYKYINKIQNLKIENLIKGDIKNGKKISKSM"
     gene            67835..69784
                     /locus_tag="KRQ43_001187"
     CDS             67835..69784
                     /locus_tag="KRQ43_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH2741553.1"
                     /translation="MERKYPNLCKPIKIGNVTFKNRMFSAPMGGTDITADCTIGSKST
                     AFYELRAKGGAGAVTISECMVHPETDGSHAYHLDLKIVDSLASFTYTADAIRRHGAIP
                     SVELSHSGQYSGTYLVDKDKKRGLSQWGVSPSVRPDGLEIKELTEEIIAEIVESYGNV
                     AALAKRAGFEMIMIHGGHGWLINQFLSPYFNKRTDKYGGSLENRVRFAKEVLDSVRKA
                     VGPGFPIEFRMSGSELFEGGYDLDYGTEIAKLLESRVDLLHVSAGTYQRGFAVTHPSM
                     FLEHGCNVYLAEEIKKHVNIPVATIGALNDPEMMEEIIASGKADVIYMARALLADHEL
                     PRKVMSNQDEKIVKCLRCFTCMAERATTSTRRCTVNPLIGRELDGTEVVSVLKPKKVL
                     IAGGGPGGLQAAITAVKRGHKVILCEKTNELGGILKGEQALPFKYKMYELGNTFGKIA
                     KDLGVEVRLNTTVTKEYVENENVDALIIAVGSEPLVPPIEGLDGENVVIVNDYYVEKE
                     KVTDEVIVLGGGLAGCEAAIHLAQEEKTVHLVEMRAELAPDANIRHRPILLEEIERQG
                     IYVYTEHKGLSVTTEGVVCMNKSGNKINIPGTSVICALGQKPRREVVDTLLDSAPYVA
                     QIGDCVRASTITNAVYQGHHAALDI"
     gene            70221..70358
                     /locus_tag="KRQ43_001188"
     CDS             70221..70358
                     /locus_tag="KRQ43_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005610222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741554.1"
                     /translation="MINENLKSLRKIHQYTQEELAEKLNVSRQSIAKWESGVSQTKGY
                     Y"
     gene            70586..70960
                     /locus_tag="KRQ43_001189"
     CDS             70586..70960
                     /locus_tag="KRQ43_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HBH2741555.1"
                     /translation="MFNLIEMLFPIMFILIFIIIVFTFVKGIATWFKNNNSPRLTVSA
                     RIVAKRQNTTHNNQPNAGDISGAHGFHTISSTSYYVTFQVDSGDRIELSVSGSEYGVL
                     AEGDKGQLTFQGTRYLTFDREN"
     gene            70976..71623
                     /locus_tag="KRQ43_001190"
     CDS             70976..71623
                     /locus_tag="KRQ43_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741556.1"
                     /translation="MNKFLSQIRRIDNEISITRKIINTIFILCFGIVLGTFAKFLDTT
                     ASNTLPFIFEYLDISNFFGRFAIWLLIALYIAIYSHSSIRASLNVLVFFIGMVSSYYL
                     YSYFVAGFFPKNYAMIWLGFTVISPLLAFICWYAKGKSKISFILSVIIIAILFNFTFI
                     YGWIYFDVYSILEVIVFGCALIALKRNTFRETTYMILSAVVIAVILNMLVPFHFG"
     gene            72003..73082
                     /locus_tag="KRQ43_001191"
     CDS             72003..73082
                     /locus_tag="KRQ43_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH2741557.1"
                     /translation="MNDMKFIETLKQKRNVCDYSQSRLAQELQINRQNLNEIENGKTK
                     ASKEMKHILLHYLDYCNCTQPFTLTIDYLRVRFPTTDALEIIKNVLAMKSEYFIHEDY
                     GMYAYEEQYIYGDISVNASKDSSMGVLLELRGMGCRDLEYVLQVRGIDWYCFLRCCID
                     YQGVFKRIDLAVNDMGGLLDIEILRERYYANKVWKRSRTHEAVDSGKLSGTHGDTAKT
                     FYIGSKNSSIYFCLYEKEKEQKSKGIKTDIKNRFEIRLKNGKAGQTVEQLVFSRNPEQ
                     TIASFILTQIDFPDYILWDIFLDNVTTSLPFIMTPVAVNMDKIKRWLERQVMPSLLMI
                     KEIEKKTGANYLEEIDRHTRLTEKQ"
     gene            73904..74117
                     /locus_tag="KRQ43_001192"
                     /pseudo
     CDS             73904..74117
                     /locus_tag="KRQ43_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
     gene            74229..75842
                     /locus_tag="KRQ43_001193"
     CDS             74229..75842
                     /locus_tag="KRQ43_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH2741558.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFERPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIVEKIFSLAYQGYGSAKITKVLREEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     ATNTANKTPYSYYACSYYGQFGKGTCSMHYIRYDVLYQAVLKRLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASAFKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITNLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEAITNEDNERIQEIEIYYRFIGKVD"
     gene            75871..76194
                     /locus_tag="KRQ43_001194"
                     /pseudo
     CDS             75871..76194
                     /locus_tag="KRQ43_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
     gene            76226..77413
                     /locus_tag="KRQ43_001195"
     CDS             76226..77413
                     /locus_tag="KRQ43_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBH2741559.1"
                     /translation="MSKIVFFSILAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIK
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFITHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            77605..78009
                     /locus_tag="KRQ43_001196"
     CDS             77605..78009
                     /locus_tag="KRQ43_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBH2741560.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYHALYVNKVMLQI
                     YDVENNNKLLRSNEELKSVKYPPIYLKYKPDK"
BASE COUNT        31327 a         8400 c        12960 g        25374 t
ORIGIN      
        1 atttataata tgtaatattt ttgttttgaa atttagaaat cagtgttact ggttaaagtt
       61 agtttagtat taagtatatt cgaagtagtt ttttagctat tttcatatct ttatattact
      121 taattatata tagcctaact aacttaatat atcagtgaaa tattgactaa aatgcctaaa
      181 tatgttatca tacaagttag tcaaataatt tggcaacatt aaatatttag taaatttcta
      241 acatttatgg aataaatttc taacaaagaa ggtgagattt atatggctgg taaaaaaata
      301 ttagcaacaa acaaaagagc aagacatgaa tattttatag aagaaactta tgaatgtgga
      361 attgaattaa aaggaacaga agtaaaatca ataagacaag gcaaagttaa cctaagtgat
      421 ggatttgcat ctgtagataa tagtgaagta tttttaaaac aagttcatat aagtccatat
      481 gagcaaggaa atatattcaa tgttgattct ttaagagtta gaaaactatt acttcataag
      541 catgaaataa gaaaacttat tggagcaact actataaagg ggtattcact tataccactt
      601 agtttgtatc taaaaaacgg taaagttaaa gtagagattg ccttagcaaa aggtaaaaaa
      661 ctatatgata aacgtcaaga tatggctaag aaagatgcac aaagacgtat agaaagagaa
      721 atgacaggta agtattaaac tagataaaac tgtatttttt agaataaaat tctttattat
      781 ctagaacata acattgattt ttattcttaa aagtattata ttatatatac attaaaaatt
      841 taataaaaat ggtgataaag tttgcgaaaa gtctactgga ctataaacta ctcaaggggg
      901 cgtaaaggtt tcgacgtggg tttggaactt gaggctgcat gtcgtgttac tctgggtcac
      961 gtaaaaactg gggaacttta aaataaacgc agacgataat ttcgcgatag cagcctagtt
     1021 gctgctcgtc cctcttagtc ctcctgccga ctaagactgg acgtcattat gcagggaact
     1081 actttagggg tgtctcgacc tgaagtagat taattgggac tggctaagca tagagcctgc
     1141 cacttggcgc tatgtgaggt gagatattag tgaagttggc taagcatgta gatgcagcaa
     1201 ggaaaagatt tgcggacagg ggttcgactc ccctcgtctc caccaatttt taaaaaagaa
     1261 tgatgaaata cttggaaata ctagtcttta ttgactagtg ttttttgttt tggagatgaa
     1321 atccaccaac cgtgccccaa ccacagaaaa agagattttt ttggggtata ttggggtgca
     1381 tttgattaat ccatggaaca tataaagaat acttttagag atatagtgaa tttgatgata
     1441 atacaataaa tattttatac tgatgaattg tttttatatt atgcttttta tttcaatcta
     1501 ggaaatatat aacttgttta aacttatgat taaaaggata aagaagttta aagcatataa
     1561 gtgctactta atctattaga gtaattacta gttataatga tatacagaat cctataagat
     1621 tatgtataag tatagaacaa atttattatc tatgtgggat gctaatttaa attttttaat
     1681 tgtatttaaa aaaataagat gtaaaaaagg aattgaaaaa tgttaagata ataaacacat
     1741 agaattatta agtttaatac taacaagact attgtatata gacaatatat tatatataaa
     1801 atttaaataa tatatcataa aagtacctat actaataagt acttttatga tataagttaa
     1861 ttctattttt ataatataaa ttaaaagtat ttaaagcgtt gttaaaggct atagtctatt
     1921 attcatcata ttcgatttcg agctgtacag gtagattgaa agctctatta aaaagcacat
     1981 tgaaatcttt ccagtctttt gatgcttgca ttaaggttat aacctttaat aaatgatttt
     2041 ttaaatgatc attacctata tcttctgtta aaaattgatg atgtttatgt tttctttgcc
     2101 caggttttac tgtggggtta actctttgaa gttcttcttt aactccagga ggtaataaat
     2161 cataaacata tttatttgtg tatgttccaa ctattccagg tctcttagaa cttggtctag
     2221 ggtatgtcca gttttttaat ctgaacattt gtctataaaa ttcatcagga aatctttttg
     2281 tccaaggtaa aaactcttta gaaatataca tagacaatat tttttgcagc tcatcacgat
     2341 ctctatcata ttgatatcct gtagcttcat caactaatgc tacaatccct attttggata
     2401 aacttcttac taaaatttcg cttgctatag ctagtccttc ttgctgaaca gctaatttat
     2461 tatcaagcct tgcttgtaaa tatacatcac atataagagg tattatttca gctggataac
     2521 cttccacaat tcttccgttt ttagtcttat attttattgt atttataagc atatcttcta
     2581 attcatctga aatataatca gatagattct ttgcatcaat aaaacttggt agattaggct
     2641 tagaaggtac acgaatttca tctttttttc taccacgctt tgttcttcca aaagctttga
     2701 atactgtact tttatttatg attcttgaac cattttctag tacagcacaa tttaaatctt
     2761 tttcacctat ttttataata ccaaaatgtg ttgctctcaa tatacttttt tcttttgatt
     2821 ccaatttaac accatccttt attttatttt aataagtaag atattactta gtatctcttc
     2881 attagataaa ttagtattta taagactaat aatatcaatt ttaaaatatg tatatagata
     2941 attgagtttt tttatcatct tgtacgcagt atttttatta acaacgatat tttttgataa
     3001 ttttctatag ctaatatttt catcaaatat aaataaatta atagcaagta gccattttct
     3061 gtagtctagt ttagttttat gcataatggt attagttgta attgaaaact tactattgca
     3121 aatattgcaa tgaaataaat cattataagt actaatttta tcagaataac aataggggca
     3181 tattaatgag ttttttaatt taagattata taaaaaaatc ttataagaga catctgttgg
     3241 aaagttttta taaatatcaa agtcttttgt cataatttaa ttatatcatg ttgtagaaat
     3301 taatttactg tatttaagtg ggtcaaattt aatatatatg tttttgatag tgtaaaaatt
     3361 aaaatataat tttaggcatg tttgtattga ataatgagca ctttcaaatt ttattagtgt
     3421 aagaggtttc aaattataaa gtaatgaatg tatattacta tatgatttat aattagaata
     3481 aaatttttat aatagaaatt taatatatca aaatatcagt tgaggatatt gttcaagtgg
     3541 tatatcttcc ctgagttaaa aaataaatga tgaaatattt ggaaatgcta gtctttattt
     3601 gtttatgata ttatgtaaca tagaatttta atatctactt tatgatataa tatttttata
     3661 aacataagat ggtttaagtt attaattaat aaaaatatat atattatata agtggatagg
     3721 agttgaggtt tgtaatggat gaaagaaaac tagaattttc tattttttgc attgaagctt
     3781 tagcagaaaa gttgaatata gattcagaag gagtttataa acttcttaaa catgatactg
     3841 atattttaga taactatata ataccttgct atgaagcact acattctcaa agtaaaagtt
     3901 atatagtgga agatttaata caagtgcttg aagaaaaggg cgtgatgtaa taattgtata
     3961 tcatgattca tactgtgtgg caaaaacgcc taatattatc ttcttaagag attctttaga
     4021 ttttggaaaa ggattctatg taaccagtat aaaaacacag gcaattaact ggatagaacg
     4081 ttttaagaaa aggggtaaaa aagcatattt aaatagctat tctctagata ttgataaatt
     4141 aaaagaaaac tgcaaggtaa aaatcttcaa tagttataat ttagaatggc ttgactttat
     4201 attagaatgt agaaatatga gtgatgtata tatgaaatat gatgttataa taggtggaat
     4261 tgctgatgat aagatttaca atacaataga actgtatcaa gataatctta ttgaaaaaga
     4321 tgaagcttta aaaagattaa aatactataa gccaaatgaa caaatatgta taactaatca
     4381 aaatgtaata gataaatatt taaagtttag atgtgaagag gaggtatagt gcttatggaa
     4441 gcaaataaaa cattattaca gatactatat aaaaaaatta tattagaatt ttctaatcag
     4501 acaggcaaga gtttggaaga aagtatggat tatttatata cttctgaaac atataaactt
     4561 ataagtgagg gtgtatcaga tatgcactgt aagggtcata tatacttggc tcaagaatta
     4621 atgctagaaa atggattaat gtatcataaa ggctatccaa gataaatagt taaaactaga
     4681 tacgaattaa ggatacaaga taatataaaa ttaatttgta tccttatttg ggttttgtaa
     4741 ttaactatat gaaatcatag tatttttatg tatttgattt ttacaatgaa aatattttat
     4801 ccaacttttc tacagcttca accttcttat cttccataac ttgagtatat atatttaaag
     4861 ttattgatat atcataatga cccattaaaa cttgtacagt tttaggagga acatcattct
     4921 caaaaagtct agttgcataa gtttttctaa gaccatgaaa ctttataggt tctatatcta
     4981 agctgcttaa tatagatttt aaattcctta aaggtctttt atcatctata gggacaccta
     5041 attcattgca aaatacataa ttatcatttc tatataattc tccagccttt aatatatcca
     5101 cattttgatt tactttatgc tctttcaatt tatttaaaac atcttttgga ataggtacag
     5161 tcctgtaaga atttgatgtc tttggttctt gctctaatac tttaagctct ctatttccat
     5221 ttttatctat aaaatatgtt ctttgaaggg ttcttttaac tgttaaatta gaatttttaa
     5281 aatcaatatc aaaccattta agtcctaata attctcctaa tctaagtcca gtaccaagag
     5341 caaccaaaaa taatacttct aatttatgcc cctctatagc ttttataaaa ttcttttgtt
     5401 gttcaagagt caatatttca agcctatttt cctttttctc aactggtata tttaccatag
     5461 tacaataatt acgttgtata agaccttgtt tttcagcttc tgataagcag gttttcagtt
     5521 tagtgtttat ttgccttata gtaggtatac ttttattgga atcaagcaat ctattgtaat
     5581 atttttgcat gtgagatact cttaagtcct ttaacttaac attgcctaaa tcagtatctt
     5641 taatataatt acgatagatg ctttcatatc tttcaaatga ctttggtttt aaatctttta
     5701 ttctatattc aaacaaccaa ttgtaaaacc aatgctctaa agttatttta tcatctgaaa
     5761 tatcagaact taaataatat tgttttttat aagcatcaag tttatcttta acttcctttt
     5821 gagttttacc ataaaattct tttcttattg gttttccatc ttcattataa ccaatcatta
     5881 tacgagaacg ccaaccatct ttatattttc cgatagagcc ttctccatta gctcttttag
     5941 ttgccatttt taaacaactc cttatatgat ttatagttat atccatcgaa gaatgtaata
     6001 catttctcta ataagaattt tataacttca tcagcttcta gtgtttcata gaagtttagc
     6061 attaatgtgt tgtattcttg tttatgtttg gctggtattg atagaactcc tatatcatta
     6121 cttataagta ttaggtttga ggtaagtcga gcagttcttt tgttaccatc atagaagaat
     6181 tgacaatagg acaaccataa atttattatt atagcctttt ctaaggggtt agttatttta
     6241 tttatgatac ttatgtcact tataaataaa ttatttaata gagtggcttc tatgcactca
     6301 tattgagtag taccagctat acctatgtta ccgtttctaa aatctccaac aattagagct
     6361 tcatcttttg caactatttt atgtatagag caaattgtat ctttatttaa agataagttt
     6421 tctttgttac ttaattttat tatataatcc catgatgatt ttatatttag tatttgattt
     6481 tggtcactta atttatgtcc acctactgtt ataccatcaa gtaatgtttg tacttctggg
     6541 aatgtgaagg ggttattttc taggttaccc atatcatata caaattcact tatcattctt
     6601 ctaatgtatg ttaaagtata ctttttatct ccatgaggta gattcgtagg gaatttatgt
     6661 gtgtattttg gtatatatga tttattcatg attttagctc ctttcatatc taatttttat
     6721 ttattaacta tgaatgtata aaagttaata ggtaaaccca tattttgaaa atgtgcaata
     6781 ctaatattct tcatcctcat cttcaataag accattagag ttttcttgta taaaattttc
     6841 aacaagacca tttatcaccc aatttagatt tttggagaag tctttgaagt cagagaagct
     6901 taagctaatt ggttttattg tatctgcatt atctgtaatt tcaaactttt ttttatagtc
     6961 tgtttttata tcataaccat aattttctaa tatgtgaact actaaatcca actctttatc
     7021 aaatactttt aaattaatat tattatttgt taaagtatct aaatcatttt cttcaacaat
     7081 gagtttattt atggcaattg ataaagcagt agatattttt cttatcatat ctagactagg
     7141 tattctttga ttttgctcat atttagctat agcatgaact gaacaaccaa tcttgttggc
     7201 tagctcattc cttgacatat ttatcgattt cctatattgt ttaatctttt ctccgattgt
     7261 attatttatc ataattccac cttaaatata tcatcaaaca atgattgtat ttttacacat
     7321 ataaaggagt tattttctag attatctata tcatatacta acttactcat aattctttta
     7381 atgtatgtta gagtatattt tttatctcca taaaataaat tagtagggta tttatatgtg
     7441 tattttagca tatatgcttt attaataatt gtaactccat ttgtagtttt ttatcattgc
     7501 tttagatagt attgatatta ttttatattt tagttagtag tttttttatt tctttaagtg
     7561 tattttcaag ctttttattt ttttccttta attcattatt ttcttgtaat aatttaaagt
     7621 aatcattatt tttaatagtc atattttctt tttgagatat taactttttt agtcgaatgt
     7681 tactcccatt atctgttgcc tcactaaagt aatcatagat tgcttctata ttttcttctg
     7741 atagaccaat atctaataat tcatcaattg attgttttat aagaacatca tttttaataa
     7801 tttcttttat atcatcagga tgtaatgaaa aatctaattc agtattagat acacaatctg
     7861 aaagtatcca attataaact tgattttcat ttagttctaa tttttcacca agtttataat
     7921 attggtcttt atcagaccaa gcacctagca ataaacttga ggtaatccta atatcatcat
     7981 cttccataag atttgaaata gcatttaaaa attcatcaaa agaatagtat tcttctggga
     8041 ataaagactg taaaaaatat aaaacatctt cattagtcat tacttcattt tcaatatcaa
     8101 aataaaagat agtcttttca atttttaaag ctttagcgag ttttgataag gtatctatac
     8161 taggtattct tttatcattt tcataattta ttagagcatt tcttgagatg ccactaattt
     8221 cagcaagttg aatctgtgtt agttcttttt gttttcttat cttttttaag ttttttccaa
     8281 tttgcaatat tatcacctcg tataaagtat atcccaaaag tacacaaatg agaacagaaa
     8341 aataatatat tcttattgac agcacacata tgtcgacatt ataattaaaa tgtaaagttt
     8401 acgaatgtaa actagaaaaa aggaggaaaa agtatgggaa tcaatttaaa aatatttagg
     8461 attaaaaaag gtttaaagca acaagaactg gcagatagag ttggtatatc aagatattat
     8521 ttgtcaaact tggaaacagg taaggctaat aatccaagca atgatttgat gattaaacta
     8581 tctagagctt tagatacaac agtagaagaa ttatttttta gtaaggagga gtaaaatatg
     8641 aaagagaata ataatttaga agttttaaag acattacaag ctactttaaa cattattgta
     8701 aagaatgaag aagaagcaca agaaaaaaag caaggatata aaattattga aaatgcgaaa
     8761 agaaataaag ctgaacttat aacatgtaaa gaagcatcta agctttatcc tataggagaa
     8821 tcaaaattta ggcagttatg tcactctaaa aataaaggtt tcccttgtat atggataaat
     8881 aatcgagtat acataataaa aaacaaattg gatgattggt ttattgaaaa tgcaaatggt
     8941 atcaagttat agtcttaaag taggtgtttg caattgagca ataaagggtg gataaagctt
     9001 tacagggagt tgttggataa atcaatttgg aaagatatta aaccagaaag aaaagtaata
     9061 ttaataactc tattacttat ggctagtcat aaagaaaatc atgtttttat agataataaa
     9121 aggataaaaa taaagtctgg acaatttatt tcttcttata gcaaaatagc tgaaagatgt
     9181 ggtaaaggag ttagttatca aatggttaga agttgtttgt tggtttttaa aaatgctggt
     9241 tttctaacat acgaaacaac aaacaaatat atagtcataa ctattgaaaa ctgggagctt
     9301 taccaagaga acatagaaaa tcaacaacct aatcaacaga cgattaacaa tcaatcaaca
     9361 acaatcaaga atataaagaa tgaaaataat attatatata gtgaaattat aagcaaattt
     9421 aactcaactt gtattgaact ttcaaaggtc aagaaactaa cagacacaag aaagaggaga
     9481 ataaattcaa taataagaga atatgataaa gaagctgtat tagaggttat aaatatagtt
     9541 agtaaaacaa gttttctgaa tggaaataat aatacaggat ggaaagcaaa ttttgattgg
     9601 ataatgaatt caagtaattt taccaagata ctagagggca attatcatag caaggaaatt
     9661 gtcataaata aagagacagg aatatataat ccagatgatt cacaattaaa gtggtaagga
     9721 ggttatatta taaataattc aaacaactta attaaaaata cagaagcaga gcaatcaata
     9781 ttaggaagca ttttattaga ctcaacaata gtagaagagt tagagcaaat gttaaatgaa
     9841 gacatgtttt atcatgagga acataaatac atatttaatg ctataaaaga aataaataag
     9901 agaaatgaag taatagatat aataactctt acagaagaat taaagagaaa aggtcatttg
     9961 aataatattg gaggtataag ctatattacc agtttgtcaa caatagtccc aacagtatca
    10021 aatttcacga gttatgtcag tatagttatt gaaaaatata aaaatagaaa tataattgat
    10081 aaattcaata agttcaatct tggagaaata gatgataata ctcttatata tcagttagaa
    10141 aatgatataa ataaagccaa tcagaaatta ataaaaaagg attcaagtat aacagccata
    10201 tcagagagag cctttgaata tataaatgat gaaatgaatg aaggtattaa gactggaata
    10261 aagttcttag atgatactat aggaggttta tatggaggtg aactaactac aatagcagcc
    10321 aaaagtggaa gggggaaaac agcattagct ttacaaatac ttagaaatgt aatatttcaa
    10381 ggaaagaaag tactttttat aagtggagaa atgagtgata tacagattct gtttagaaat
    10441 atagcctcac taactggaat atcagttgta aaaatgaaaa atagaaatct aaatgatgat
    10501 gaaatagtca aatatataca agctttaagc ataataaatc aagaaaataa cctttatata
    10561 aatgactctg taaatacagt atcagggata aagagagaaa taaagagtac taagcctagc
    10621 ttagtcataa ttgattattt gcaaattttg gattatgaag gtaaagaagt aggagaagct
    10681 aaatttgctg acttatcaag gcaaataaaa aagattactt tagattttaa tataccagtt
    10741 attcagcttg ctcaattaaa tgatgaattg aaggatgaaa gacctaaagg ggatagagta
    10801 atgagaagct caaagcagat atatatggat tctaattcag ttatatatat tcatagacct
    10861 acagaaaaag aggctcttaa ttattgcaag acaatgggaa ttgaggatat aagagagttg
    10921 agacgaagag aaaaaggttt tggtgctaat ttaagtgaga ttattgttgc caaaaataga
    10981 gatggtgagt caggatttag accatattgg tatataggaa atttgttttc ttttgaagaa
    11041 tgtaagaaga tacaagagat ataaaaaaga agcatgattt attaagtaat agataaatta
    11101 tgtttcaaga agtattgaat ggtaaatata taaaacttaa ttagatgtaa tagagattta
    11161 aaatatattg agtttagatt taaatgctta ttagaaaaag gtagttgcca tataaatata
    11221 acaactacct ttataaatta ggtacttaat gtacactaac ctagcaactt aagtatatat
    11281 taagtacctg atgaaagtca aggaggtact aaaatgtatg atgaaattat agaaatatat
    11341 tttgattatt ggataaatga acatatgtat agaagtattt tagaaaaaga tgagtattat
    11401 attgaatgtt ggaaagaggt taaaaaaatt aatgagttat tggaaataaa tttggaagat
    11461 gataagaaat atctgttggt tgaattaaat gatttgttta attcattaat agaatttgaa
    11521 agagaactta gttataaatt aggatttaaa acaggagcaa aatttataat agagttgttg
    11581 aagtaattaa tttgtgtatc tcaatagaat aattaaatag taaatcgaga ttattaataa
    11641 gttgtactag aatattttaa gtgaagtata tattaattat attgtttaaa ataaatatat
    11701 ttaataaaga ggggataagt atgccctctt ttatttttat gcaatcaatg acattgtagg
    11761 atttacgtat tttgataaat agcacaatat attttaataa taaatatatg atacaataat
    11821 tttattaaaa tctaaaataa tcaattgagg aggagaatat gataatacct aagttagagc
    11881 ctaatgatag aaaaagagag tttaataaat actcatcaga gcaaataaac aaagtagttt
    11941 ataattattt atttaaaaat aatatgagta atagaaagat agatgatgag atactagatt
    12001 tatcatcaaa acaaagtaaa ggttatcaat caatgggtat agtgcatcat ttaggaataa
    12061 ataaaaatca taaaggtatt tttacaggat acacaataga taaagcaatt gaagttctta
    12121 aggaagatga gatacatttc aagcagatta ttaatatact tttagaaatt agaaatataa
    12181 atgagtatcc tataatagtt gactcttggg agttattaga tgagaaaata gctttaaaaa
    12241 caattgataa atctacatta aaacataatg ggacaggagt tccaatagaa ataagatatt
    12301 tttttgagat aaataattta ggaaagaatg aaaagaaaaa tgtgaatttt aaatataatg
    12361 ataattatta tagtgcagtt atagagatgg ataaattaga gaatccaaga agtagaataa
    12421 tttggaaatc taagtttaga gatttactaa gaagtatatt ttctgagtat tatgagaaat
    12481 tcttagaaaa taaaatagaa ggaaaaacaa atttacctaa aataagattc ataaaacttg
    12541 atagtaataa ttttaacata gaattcattt ttactgctga aatagaagac gatgtattag
    12601 aggagataag tcaagataat cctttgaaca ttaatactat taatatagaa ttagaaactg
    12661 aaattagaaa agaagggaaa gttaaatatg tttatgggaa acagtatgag cgtaacccca
    12721 gaaatagaat agaagcaata aaatatcatg gcacaaagtg tattgtatgt gggtttgact
    12781 tcgaaaaaac gtatggagat agaggtaagg gatacataga aattcatcat attaaaccat
    12841 taagttctgt tggagaagaa agcaatataa atcccaaaac agatttggtg ccaatatgtt
    12901 caaattgtca tagaatgatt cacaggaaga aagataatgt tttgagtatt gatgatttga
    12961 agcaaattat aaaagatagt aaataatgct tatgtgtggc agagatgtat aaagtatata
    13021 ttctaaacta gttaacaaca aatactaata taaaaaatca aaaaatttat taggaaaagg
    13081 tagttgctaa agtataacag ctacttttat aaattaagta tttgaggtat attagtctaa
    13141 ccgattaggt atatcttaag ttattgatga aaattaatta agactaacat gtatgatgaa
    13201 tccatagaaa tgtattttta ttgttaaata aatgaacata catagaaata ttttagaaaa
    13261 ttacaagtac tatattgaaa gtttgaagga gaaccttgat ttaaggtaag tgtaaagttt
    13321 ttagaaactt cactaaaata atctaattaa gttatatatt tgttactttt aggaaaataa
    13381 tggtaaaaat taaaggtttt tataaatgaa tgtctaattt tataaataaa atggagtatt
    13441 ttaactaaat atttgaggag ataaaatgat attaaataaa atcgaaataa ttggagatat
    13501 ggctcacttt aaaattccta tgcatagcaa gatacaaaga acatatgaaa ttccaccaat
    13561 atcaacagtt gtcggaattt taaaaaatat atatggtgaa gaaatagatg attttatatt
    13621 aggatatgtt atatatcatg atggtacatt taaagattta cagactatat ataaagaaat
    13681 caatccaaat gtaaaaacat tgacagatag cgatagattt caaactgatg tatgtcccat
    13741 tgaataccta attaatccta aacttatcat atatactaac atagataaaa atatagaatt
    13801 taatgagccg ctatgtttag gtaagactaa ttgtttagcg aaggtattat ctttaagtga
    13861 aattgaagta aatctaatag ataaaaaagc tattggatac aatcaatata cagatattaa
    13921 tattggagat ggaatgataa aaagaataaa tacattgaca gagtataatg aaaaaaaagg
    13981 ttattatgat atatattctt caatggtaag agaaaatgat gagtttgaat atggtaaata
    14041 ttatgatgaa gatgagcaac agaatatttt tttatggaaa tggaaaaaag ggggagtaat
    14101 taaatgcatt tagtaagaag acatttgata ctcacagtgg ataatgaagt tgtattagat
    14161 tacaattacc agtatgagct aatgaaaagg atatatgaag ctatagaaat taatgataaa
    14221 agaaaagcac taagtcttca caatgaaggc tataaggtgg ataagaaagt atttaaatta
    14281 tttaattaca caattatgtt tgaaaatgct aagtatttaa aagagggaat acatttaaat
    14341 ccccaaacaa aaatcaaatt aattttaagt ggatatgatg atatattgaa taatattata
    14401 aaaggtttta ttaaatgtaa agtatttaaa ttgaataata tagagtttaa agtttcagat
    14461 atagaagaag attcaaagaa aaattttaat aatataacac tttataaagt aaggtcacct
    14521 attgtagcaa gtttatatga tttaaaaagt aggaaacaag tatacttaaa tccaatgcaa
    14581 gaagagtttt ataaagcatt acatgataat ttaggaaata agtataagct tatacataat
    14641 aaagaatata ctggtgaact atactttgat attgaggatg tattagcagt aaaaaagaaa
    14701 tatataacta atataaaagg aaaaggattt ataattggat atacagattt tgaaatattt
    14761 gtacaagcta ataaagatat gcaagaagta atttattatt gtggattagg tgaaaaaaat
    14821 agtataggaa tggggttact aacttatata acttctagga gggcttaata tggatagaag
    14881 ttacaatgta tttgttgata atggtctata tgtgttggct tattatctga acaaagatat
    14941 taatgatata acttatcaag atatagagaa tagtatagat ttaatgagtg ataaaattga
    15001 agaatttgta agttgcgaaa aatactctaa tttaaaaagt atgtgcttta gcaattctac
    15061 gctaactcaa ccaaaaggaa aagttacttt aaatgagaag ttaaaaggtt ttgttaaaaa
    15121 tcaaggagat gaatattgta gtttatgtgg tcaatataag gccaaagtca aaattgaaga
    15181 taaagaatac aatataggga gaagttatat gcctaatttg gttgcaaata cattttataa
    15241 tttctccaat aatttgcaag gtttgaatgt atgtccatat tgtttagtat tgactatgta
    15301 ttcaattctg aattgtagag taagtaggta tgctttttta tacaattcta catcaagcga
    15361 atttatggaa gattatactt tccatattca aaaagaaaat ttaactgatg tagagttagg
    15421 agcaaagaaa gaaaaagaaa agtattcaat tgtaaaatta ttagaaagtc tagtgtgtaa
    15481 atataactta tttaatggtg atatagagca atatatgttt aataactctg gtcaatctca
    15541 ggatattcag gtaaatagaa taaaaaataa atatgtgaat ttattaataa aattacagga
    15601 aaaagcacta ctatcaaact ttgaaaagtt acatttggat aggtatatct tgaatggtac
    15661 tttagaaagc aattatctca gagaagtata tagggtaaaa aaggaagaaa aaatggatga
    15721 gaaagaacaa aagaattttg atgaacttgt tattttttta aacagggagg taaatgtatt
    15781 gaaaaaagtc aaaatagata taataaaaaa attaacggat aaattaaaaa ctagtgactt
    15841 agatatagac aaaatatata aggagcttaa aatgttagga aaattttatg catatgagga
    15901 ctggttagtt aacttaaatg aaatgtatta tgaaaaaact ggagaaaaac tatttgaagc
    15961 agaggattat attgagttgg atgatataag aagctttaga cagattaaaa atttaatatt
    16021 agtaagttta atttaataat attatggagg gttaaaatgg aaaataaaaa ttcaaataga
    16081 atgttaaata taggctatgc aatagaagtt ttatgtgggc gattaaatgg aagtagtagt
    16141 gaagtagaaa agaaaaataa ttcatataag aattctactt atactaaaaa aatagggagc
    16201 agaagtagaa tctcaagtca atgtcaaaaa tacaatcaaa agctatttat ggaacaagtt
    16261 tgtggttatg aacaaaatgt taaaactaaa gatgggaaac aagtaaaatt ggttccaaac
    16321 ccatttaaat atgcgacaga tgatatattt gggtttatga tggcggaaaa attatctata
    16381 gaagaagatg tatacaaaga attatcagat gaagaaaaag aaatatataa aaaaaataaa
    16441 aagaaatatg aagtaaatat aactaaaaaa agaaagtcaa gatggcaaat gaactcttta
    16501 ataaatgtat caaatagaaa agttgaatgg gagtggaatg tttgtggaac tacaggagat
    16561 agtatgccat atcaagttga ggtatattca ggggtacata caaatatagc aaatcttaat
    16621 ataggaaaga taggagaata tgatatatct gatatagcaa gtgagcatag agattataca
    16681 actttagaag ctaaatcaat tggagttgaa aagttagata aagaagaaaa gtttaaaaga
    16741 atagaagctc tcctaaaatc actagaatac ttaagtgtag aaggtaataa gacaaatcat
    16801 ctaactgata caaaacccaa atttgttata ttgggagagt attcatgggg aaataatgta
    16861 tttcagggta ttatcaaaga aaatggctta gatgtagaga tgttaaaaga atctatagaa
    16921 caaaatgaag aatttagaaa aagcgatata tggattggaa taaataaatt ttatgatgat
    16981 acatttaatg agatagaagt taataatgaa aaggaacaaa taaagaagta tttagaagaa
    17041 gagtttgaag agtatgattt tatgaaaata tcaaatgtac atcaagcttt tgaaagttac
    17101 ttaaaatatt taaaggagac tttataaagg atatatcatg aataatttat atgaatataa
    17161 agctaaatca gatgggacaa gtatagataa gcataatgaa gatatgaatt acataatgaa
    17221 tcaattagtt agcatatata atatatctaa tgatatgaaa aatgatttat atgaggcaat
    17281 tgtatgtcat gatgtaggga aagtagtaaa aagctttcaa gataatattg aaagtagcac
    17341 aagaagagtt agacatgagt tattatcagc aagtattaag tatttaaata gaggtcagaa
    17401 gttagctata ttaacccacc ataaagatat aaagtttcta gagggtcaaa taacaaattc
    17461 tatttatgaa attgaattaa aggaattaaa ggaactatta gatattgaag tagaagatat
    17521 aagaccattt ataaaggaaa tatcaagagc aagaaatgat gatactagaa aacttgaaaa
    17581 tatattatta aaaggttact tgcaatattg tgaccatata gcttctgcgg gaattaaaag
    17641 tatagataaa ggatttaatt ctattaaaga ttttagtata ccaaagggtg taagttataa
    17701 ttcaatacaa gaaaaagttt taaatatgga taaaaatgaa gatataatga taatggctat
    17761 gacaggtctt ggaaaaacag caacatcatt gtattggagt aacctagttc aaaatgaata
    17821 taaaagtaag agagtgtatt atatacttcc ttatacagca agcataaatt ctttatatga
    17881 aaatttatat aatagaaata taagcgtaag tatgttacac agtaaagctc catatttttt
    17941 gaataaaatt agtgatgaag aagatataaa acaactttac cagatataca aaaagagtgt
    18001 aaaacaaatt aatgtatgta ctatatttca attagtaaag tcagtatttt cttgtaagag
    18061 atttgaaatg ctactatcac aattaaaaga tagtatattt atagttgatg aaatacattg
    18121 ttttgataca agagtattgt gttatacatt ggaattttta aaatatttaa aagaaaactt
    18181 aaatgtaaaa atatgtataa tgagtgcaag tataccaact tgcttaaaaa agttaataca
    18241 ggaaagattg caaataagta caattattga accagatagt aaagatttaa tatttagaca
    18301 tagattgaat agattaagtg aaggaatact tgatagcata cataaaatag aaaatgattt
    18361 aatgcaagga aaaagagtat taatatgtgt taattcagta gatttatctc aagagttata
    18421 tggaaggctt caaaaatata atcctaaatt aatacatggt cgatttaata ctagagatag
    18481 agagcaggca gaaaaaggga tagaagaaag cttcttattg ataggtactc aaagtataga
    18541 ggtaagttta gatataagtt atgatgttct ttatacagag ttagctcctt tagattcatt
    18601 gttacaaagg tttggtagag taaatagaag gggagataat gctgagttga gcaatattta
    18661 tatatatgat tatgatagaa agcttaatat atatgatgaa gatataataa ataggactga
    18721 tatagtaata tcagatataa tacataatga taattctata gttgatgaga gtaaagttcc
    18781 atcttattta gataatgtct atttagatat agatatggat aaatataata aacataaagt
    18841 tgctttagag attataatga aaaatatgag gttaggggta tggaataaat ctgctaataa
    18901 tgatatgtta aataatgata ctattagtgt tgtgcctgaa tgtcttttag aagagtacaa
    18961 gttgtatatt gataaaaaaa tgtatttaga agcgagttca ttatttgtaa atgtatctgt
    19021 aaaaagatac aattataata aaaagatgtt ttatgaatgt ggagatatag ttgttacaag
    19081 ttatagttat aatgataaac taggtctaat atttgattgt taagagaatt atagtataac
    19141 taattaaaat attttattga gaatttgtta taatttatat cgactacaaa ttttatatgt
    19201 tacaatagaa taattttgca gtgagcgaaa aatatgtgta aatggctgtg agttagtgat
    19261 ggcaaggttt ataactgaat ttttgttttt agctaaaaac actactggtg cctcactgca
    19321 aattaactat tttaataacc ctacaagtgt tgtaattact atagttttat ttggggttta
    19381 aattacacta agttagttat aaatattccg gaaagtactt ttgctatttg attcattcta
    19441 cccgtttaaa ttacactaag ttagttataa atttcactaa ttttagttac aactattaca
    19501 agtccagccg tttaaattac actaagttag ttataaatta tgtgtaatgt attttaatgt
    19561 tttctagcaa caatgtttaa attacactaa attagttata aattttataa attctatgaa
    19621 taattttaaa gagaggtttc gtttaaatta cactaagtta gttataaatt gtacatttga
    19681 catagaagct tcaaaatcca tcccagttta aattacacta agttagttat aaatgtaaca
    19741 gcacgaatga tggcacagac ctatctgcaa tgtttaaatt acactaagtt agttataaat
    19801 agaagtacac ttacaagtaa gataaaagac ccaggtacag tttaaattac actaagttag
    19861 ttataaattc tgtagctata tgtggaagta attttagtag agaggtttaa attacactaa
    19921 gttagttata aattattgaa ggggtgagag ttgtgactag gcactacaag tttagattac
    19981 actaaattag ttgtaaattt acttattcat taagaaactt aactgagagt ttgatttata
    20041 ttattgaatt agcaagagtt ttagaaagta gaaaattata ccccaataat accccaacca
    20101 caaaaataaa taataaaaaa tatccaaaaa aattagtata acatcataac taaatagcta
    20161 tatacctaca cttacgaaaa ccaacaaaac aatcaaataa ccacttgtag actcccctcg
    20221 tctccaccaa ttttgaaaat gaaaataata gaataaaagg aattacttat gtttggacta
    20281 agtaattcct tttattttgc ttaaaagcac acaattagca cacaactaga aggttatata
    20341 aataaaaagg ctgtcgcact agaaaatagt gctacgctct tttttgtata aaaaaataaa
    20401 tcccaagttc aaaagaacct gggattcttg tataataact gtatgctaaa acaaaatact
    20461 acacaaattg attatactac ttatggtgat aattatcaat ttaagctacc actaaatatt
    20521 gattacatga ttccaaaaga tgattctgta aggttattaa gttaaattat tgaggagatg
    20581 aatttagaaa aattatataa gacttattct cgaattagat gaaatagagt aatccataga
    20641 caatttttga aagttataat atatacagat atgaactgta tttattcttc gagagaaata
    20701 gaaagaacat gcaaaagaga tattaatttt atgtaccttc taggcgaaac ctccactcca
    20761 gaccattcaa caattgcaaa atttcgcagt atacattttt aactaatagg caaaagcttg
    20821 attgcacagt ttacaaactt tcttggagat aataatgaaa tttcaaaaga cacaatattt
    20881 attgatggta caaaaataga gtcatctgct aatagatata cttttgtttg gaaaaaagct
    20941 gtaaataaaa atatggctaa aatggtgaat aatatatctg acttcatatt gaaatgtgag
    21001 attgatgttg gcattaaaat agtttatgaa gataaaatta aaatctatca tttaaagaaa
    21061 ctaaaaaaaa tatcaaaaga agcaaatgta gcatttattc atggaaaagg aaatagaaaa
    21121 tctactaaaa accttcatat aatgggtgaa cgaaatagtt gttctaaaac agataacgat
    21181 gaaactttta tgagaatgaa agaagatcat atgaaaaatg ggcaactgaa accagcatat
    21241 aatatacaat ttggtgtaga ttaagaatat atagtttggc taaattcagg aaatcaaact
    21301 gctgatacta caacattaat accattttta aaatctatag aggaatatac taagtttaaa
    21361 tatcctaaag taatagctga tggtggatat gaaagtgaat aaaactatgc atttttagag
    21421 cataataatc agttatcttt cataaaacct gcaaattatg aaattattaa aactagaaaa
    21481 tataaaactt atattggatg tattgacaat atggattatg aagaagaaaa taattattat
    21541 atttgtacaa atgagaaaaa actatttgct aataaaataa taaataggaa atcaaaaaca
    21601 ggatataaaa gtgaaataac atgttacatt tgtgaagagt gtagtaattg tcaatataaa
    21661 agcaattgta ttaagagaag taatagtaag gttcctctta aaaataggac taaaaactta
    21721 caagtatcta agtcgtttca tgaaaaaaga aaagaaaact taaagagaat tatgagcctc
    21781 gagggggatg aacttagagt gaatagaagt atacaagcag aaggagcttt cgctcaagta
    21841 aaataaaata tgaaacttac aagattttta agccaaggta aagaaaatgt tttataagga
    21901 tatattattg tggcgatagc ttataacgtt tctagactac acaataaaat agtaaaaaat
    21961 aaacgtggaa tatatcttta tcatttaaaa aaatattcta aaattattat ttataatcaa
    22021 atattatctg aaaaaatggt atttttatat ctttatttgt catgcataat tttacttaga
    22081 acagaaactt tatataaaac aattgaaaat atacctatta agataattag aaaagagctc
    22141 tcacagaaca aatttaattt gctcatgcaa cagccccata ttgatataca tttaggttgt
    22201 ataattatac atttcaatat tacatgttca ttaggataat agttagtaaa tgatatgatt
    22261 gagagaatag atataataaa ctaatctagt cctgtattgc aatgtttatt aaagaatata
    22321 tttttaaaga tccaagtact gcatctcttc cagaattgag ttggttaata gttttttgat
    22381 gctatgcaat ttataataaa aagtataatg atttagttga tgaatcatca gaatttatac
    22441 cctcaaagat taatcagatt gcaataaaaa taatgatata ttctatagtt ataatatcta
    22501 ttttctttgc aacccctcat acaatgaata taaatatatc aaacttggat atgggtataa
    22561 ttctcatttc agttttattt atacagtttt tatctaaatt aattttgtat gtatattttg
    22621 ataaaaggga gatatgtaac taagtggtaa tattggtgaa aacaaaaatt aaagaatata
    22681 gaaaaaaact ccttatgaca caaaatgaac ttgctaaatc agttagggta aggtgtgaga
    22741 ctattgtaca cttggaaaat ataatccttc tttaaagtta gtgatagata ttgctaaagt
    22801 attcaatact acagtagaaa atttgtctga atttattgaa gaaggatagt ggatagatta
    22861 taaatagtta taagatggtt aatgaaatat agttacttaa ttattaagtg tgttagaaat
    22921 atttatatgt aacacaatgt gtagttaaga ttaccttatc tcatctaaga ctttaatttt
    22981 tcttcccata aagagggtat atcaattttc tagtgtggta gcccattttt tattgattta
    23041 aatttataat atatattaat agatgatact taaaaatttt ataaaatatc taagttgtca
    23101 taaataaaac gatatatcta accgaatatg gtaaaatttg ttataatata gataagttag
    23161 agtaaaaata attttaatgg gggagaaaat gcagtcagta atatgtaaaa tttttgataa
    23221 taaattacta attagtaatg atttaagtga gcaggatgat gtattatatg aggtaatgga
    23281 taaatttata gatgatattg aatatatttc aaaattagga gatgagcaaa ttaaaagtat
    23341 gcttatggag gtaaataaat ttgaagaaga ttcaactgaa tttgaactat atatgaaaaa
    23401 cttatgctat ttaaagcaat catattttat agatactaat gataaaagtg aaataaattc
    23461 tatagatata gatatattaa aaaatgttaa aatagaggac ttagttgata taactaatat
    23521 taaattagaa cgaaatttaa atataaatat agaacatata tctaaagctg taaataaaat
    23581 atatgaagaa aatgaaaagt ggaaagagta taatatacaa aatactatgt ctaaatatat
    23641 aggtatacct gaatcagaag ttatatttat atcaaatttg agtcagtatg tttcattttt
    23701 atctgaacta gataacgcag gcgactatgt atctagaggg caaaaagatt gtatgtatga
    23761 attattacca tcattacata gaaaatataa aaaagactat ggtatacatt cagatgaata
    23821 cgaggaagca ttcaaacaaa aaataattta ttatgataaa gaaataaaaa atagatcgag
    23881 tgaagaatta agagctgaag ggcaacattt tggactacca acagaatatt tagatttcac
    23941 agaagctcat ttaatatcat tattatttgc aatagaagac tataaatata caaaacagca
    24001 ttcaattgtg tactttatag actctatttc ttataatact gacactataa aaagatctga
    24061 gaagttagta aattattcag atacatctgc aatagataat tgtagtaaat tttcatcaag
    24121 atcatttttt ataaaggtag ggaattcaaa tgaaagaata cattttcaaa aaggatgttt
    24181 cctaaaagta tcatcagaag ataaaggcga atttaaggaa aaattaaaaa agtattgtaa
    24241 agtagtagtt attaataaag atgctaaaaa agaaatatta aaagaattat ttaatttagg
    24301 tattacattt gaaaatattt atccagataa agataatgta gttaaatcta taaaattcta
    24361 ttatgatgag atagtagggg gaaatttata atgagagaac aatttaaaaa ttctataaaa
    24421 aatattaaat caaacagacc tcttgtatca gtccaagata ttgtgaattt tattgataaa
    24481 ggagaaaagt acttgaaatt atcaatagat gaaatagatg aaatggaaat tttacaagga
    24541 atagttatga gtcctgatta tcaacgtaca tataaatcat caaacaagga agaaagttct
    24601 ataattgaat ctcttttaat tggaatacca atacctgaaa tatttcttgt aaaaataggt
    24661 gtaaatgata tgcaaataag acatgtaatg gatgggcagc atcgtttgaa tgctatatat
    24721 aggtatgtta agaataaata tccacttaaa aatttagata tattaggcaa tgacccacta
    24781 tatgataata aaaggttttc agaattagag aaaaaagata aaattaaaat attaggaagt
    24841 catttatcaa ttctagaatt tgatggtttt gataatccag aaatagaaat agaattattt
    24901 aaaagatata acagaaatac aaaaccatta gagatgcaag aaatcgagat ggcaacatat
    24961 ttttcagaaa ctagtaagta tataagtaaa tttataaata ctctaataaa agataaatat
    25021 aaggatgaaa tagataaatc agaatataaa tatgctaatt acaaatcaga tttacttaga
    25081 atatataaca taactaaatc tcgtaatgat aaacaaaaaa atcatcaaga aatatgtata
    25141 atatttagta ttttagaaaa tgggctacaa gaaaatatca gagatggagt tacagcctct
    25201 aagaaatttt tagagtataa gtcaattcag tataaaaata atgaaagtga aaaattagag
    25261 ttattaaaag ataagtttga tgagtttaat aggatgatac tgaaaatatc tgagaagata
    25321 gaatatccat tctcaacaag tttaatatct gatgataagc aaagacaaag taaatacttg
    25381 ataggagtat ctattgtgtt ggcttctatt tgttattatt atgatataga cttggaaaat
    25441 aattatttaa tacaagatat taaaaaaata atatcttgtt cacccatagc agatatagaa
    25501 tataaggcgt cttcaactaa tatgaaaaat atgattctat acttatttat aaagaataaa
    25561 atacaagata ataaatttga atcattaaat ttaaaaagag ataaaattaa agaaataaat
    25621 actttagtaa tgaataatga tggttattta aatgaacaga caaggctatt agaaatatat
    25681 taacaagtta taaaataaat catggtaatg taaaataatt tgtgctttta aggttaataa
    25741 aaatcttctt tatggcaatt atttaaatat aatcaaatgt cgtaaaggag attttttatg
    25801 aacgctttaa gaaaacaatt agccaaagaa attatatcag atatctaaaa aagagcatgt
    25861 caaataaaac cctaggtatt taaatttttt tagagctact taaaataaat tatgctatct
    25921 ctgtatttaa atatttccta aattcaagtg gagacataga atttaatctc ttttgatatc
    25981 taaaattatt atagtaatat atataatcct ctattgtttt gactaattgt tcgtatgtat
    26041 caagttttct taaatagtac atttccactt ttaaaattct ccaaaatcct tccataggag
    26101 cattatcaat acaacgagca actcttacat actttgtatc atgccttgtg ttaaaagttt
    26161 tgatttaaat accttactag tatactggaa acttttatca ttatgaaaaa taggttttgc
    26221 atttggatat agctctattg ctttatcaaa agtttctaac accaagttat tgttatttga
    26281 ctttccaata acatatgaaa ctatacttct atcgtctaaa tctagaattg cgcttaaata
    26341 ggccttcatc ccattggtta atttaaattc agttacacct gttaaccatt tttgagaggt
    26401 tttatctgca ctaaattttc tacttaatac attttccgcg atcacttctg gcgtacattt
    26461 aacataacta aatttctttt ttctgcaaac agaacttaag cctacggctc tcattagtct
    26521 gtacactctc tacaatcttt aacaatttca actctttcat ctaatgctgt ttttctagtc
    26581 tccataaaga tttctccctt cgaggtttct tttatctact tatgaggatt atactcttta
    26641 ccccaagctt ttagtgaata aactgatctc attttatatt tttttgagat tgtgtcataa
    26701 gatccttcac catttagata agattttata gcattcaatt taaattcttc acaatagcat
    26761 aatttacaac tttgttttat taaaccatca tttccaaaag cttcataatt tcgcatccac
    26821 tctctgaatg tacgtttatc caatatttaa ttcttccatt atttttatta ctgtattctc
    26881 accttttaaa tatgattcaa ttgcttcgat ttttttgctc tgaagatatc ttagttttag
    26941 atagtcttac atattttaac tgtctcctaa gatgagtata attcattcat catcagttct
    27001 atagaataca cctagttcct acttactgta ggaactagga ctatatgaaa cccattcata
    27061 gattgtagtt tcttctgttg cattatagcg cagaatagta aattcatgtg aaattttatt
    27121 ttgaatttac tatttatata taaatgaaga gtggtcttat tttcaattaa aatttggaac
    27181 aattttgggt tgacatctac aattaaggat ttaagttttt gttatactaa taaataaaaa
    27241 cagagattca aaatatataa ataatactta aactagtgct gatagatttt ctttaagttc
    27301 tagttttttt attgtcatta tctaatatgt actattttat gtacagtcaa tataatctga
    27361 aattgtaaaa tggtgtataa tatagttata agtaaagaag ggatttaaac atgtatgatt
    27421 acaaaaataa aaaagactta tatatacctt aaggaaatac aaaaaatata caaaatcaat
    27481 gagcataaag aactagtaca cataataaaa aaactaataa atgataataa aataaaacca
    27541 ataaaaacct cagatctaac acctcagcat gagcaattat atacaaagta tagaataata
    27601 aaacaagaaa cagaagaaga taaaaaaata ttagaagaaa taaattacaa aatatgtgat
    27661 aaattaagta tagattatta tagaaaaaac ttagtacact ataaaaataa tagagttgca
    27721 ataatggatt taaatagtta tcttattaaa aaatctgata atctatcaaa gaaaatatcg
    27781 attaacgaaa gatcttatga aatatttaag gatgagaaat tcataagtag taaagtagga
    27841 aaagaagtac taaaaaactt aaaaatagat ctaataaagg atttaaacgt atataagaca
    27901 ccagagccat tcatatattt atcaataaat cgtatatctc cacaaaaaat attaattata
    27961 gaaaataaag acacttacat aacaataaca aaaatgctat tagaaggaaa agaaatactt
    28021 aaaaataaaa tagatactgt tatatacgga gaaggaaaaa aaataatcaa cagtattaaa
    28081 ggattaaagg aagatataac aattgaatat cttacaaata aagaaaatga atttttatat
    28141 tggggagata tagataaaac tggattatca atatacactt ccctaaaaga taccaatgaa
    28201 attaataata taagattatt tgaagttgct tatgagcata tgatagataa aacaaaggaa
    28261 aataccttga ggaatatccc caaaaatcaa aaagataatt ttgaatgtgg attagaaaat
    28321 attaataacc taaacttaaa agaaagtatt aaaaatattt tagtacaagg aaaatacata
    28381 cctcaagaag ctctaaatag attcgacttg gaggaatata actaatggaa atgattaata
    28441 ttttagaagg ctacaataag agagtaaact gtataggatc ttattatctt attgcaactc
    28501 ttgctaacaa tagaaataaa tttaaagaat ttgacaacat tcaattttac aatttattaa
    28561 ttcaagtttt gtgttatata tttgatagat ctcttagaag aaagaactgt ttaagagatg
    28621 atattaagga ttttattgaa gaaataaatc gtatggatta taaaataatg ctttcagagg
    28681 atgacttaaa ggatttagca aactatataa ttaatggatt aaccaatagt ggtaaagtat
    28741 atctatttac ctactattct ttagaacaag aaaaacatat agatgaaagt attaaaatta
    28801 tagaagataa aaatgtaaaa ataaataatc aggaaagact atcctactcc ttaacaacag
    28861 agggttatag attgttgtta tcaacaaaag aatatgatga actattccaa attcaaatat
    28921 cacaaatgat tgcaaagtta aggatagaaa agggtgatta tcaaggcgca aaggaagata
    28981 tttacgatat aataaatacc ttagagattc atcaacagaa aattgataat tatataaaaa
    29041 taataaaagt aaatatacta tatataaaag aagaaaaata ttcaacagta atagatacaa
    29101 ctgtagaaac acttttagaa gaaatggaca aatatgaaga attaaaaaaa gaagtaaaac
    29161 tattaatcaa agataaagag gactacttgg aaaaggatga ggatatagac aaagaaaaga
    29221 taaaaaatat aagaactcaa ctattacaaa tgaaagaatt aatagatgga atagttttag
    29281 caaagtctac agccacaaat ttgttatcta gagttcaaga ttttagagaa gaatttaaag
    29341 aaatacttaa aaaactatta acaactccag taattaaaag attcaatttc aaggaagaaa
    29401 tcttagatag acttgaaaaa gacagtgatt ttttattgat aataagagaa ttatatatat
    29461 ctttatttaa agtagagttg ccaaatcgat ttaatattgg agtggcatat caagaacaga
    29521 aactattaaa tactagagaa attgaaaatg aaatagttaa taaagacgag ttagaaatta
    29581 ttgaaaataa agagaaggag gaacgtataa attattgtga aaattactat tttgattttt
    29641 ttaaatactt aattaaatat ggacttgaaa aaggacaatt tacattagaa gaatttctaa
    29701 aaaattatct gaaatatgac aaagttattt acttagaaat aactaaagac tccaaattga
    29761 tgagagatat aataatttac ttcgctaatc aaagggaaag tatcaatatc aaaaagataa
    29821 tcagaatgtt agaaaatagt gccttctcac caaatacaga ttttcaaatt gaaagattaa
    29881 tagaacgttt attagtagaa gattttgaac tattaaatag cgttagccat attaaaagta
    29941 ataaaatatt tgaagatgaa atgaaaataa atactgaaat aaatttagaa actatgactg
    30001 cagttaagct agaaatagca aatataaaat ttgaaataat ctaaatataa ggggaaatac
    30061 aatgaatata tctttaaatg actataaaat agccaatgaa atattttata gattacttaa
    30121 aaaaagtgag ttaaaagaaa aagaagctaa agaattattt ttagcttata taaataacag
    30181 taatgtaagg tatgctttag aggcaatttg tgaagtatct aaaataaaaa taatattaat
    30241 ttcagatacc ttatacttaa taccaaataa tgacaatgat atttttgggt ttgactatag
    30301 aagagaatct ttattaggga aagatttaaa agatagttat ttaggatatt tgataatgac
    30361 aataatattt tctgaattta caaatggggt agcaccagca tcatatattc aagtattaaa
    30421 cttactggat ttagtacaag aatccttaga acgttcaata gctcgtgata atctagaaga
    30481 aatagaaaaa tcatgtgagt ttaatataac tatcttaaag aactattggg aaagtaaaag
    30541 aaagtgggac gaatctagta agaaaggaat agaaacaaca tcagcagatt tccaaatagg
    30601 gtttattaga aaaataatta atttcttaaa aaatgaaggc ttaattgtac acattgagga
    30661 tgaagataag ataaaaccaa ctagaagatt tcttgatctt atgaataatt attttttaga
    30721 tgaagaaagg aaagtattaa tagaaaaact agttttaaga aaaggggaaa gtattaatgc
    30781 cagtaattaa taaatacaaa attataaatt ttaaatttgg tatgggacaa gaaagaatac
    30841 ttagcaacag aaccatggaa ctgtatggag aaaacttaca agtagaagca gaaaatacag
    30901 caggcaaaac tatgagtatt caaactatca tacaaagtat ttgtccacta tcggatgtag
    30961 ccaaaccgtt tactgcaata tataataaaa aagaaccatt atactcaatg actgaatggt
    31021 tgctagatga tggtaaaacg ttattattaa cgggaatagg atttgagaaa aaggctggat
    31081 catctaaaga agaagggaaa gaaaaaaagg acgatttata caaatacttt atgtttatta
    31141 tagaagaatc taaagaaatg gaggttgata tagataatat acctttatta aaaaacaatg
    31201 acaaaggtat aaggatagta caacctttaa cggcctcaca agactatata aaaatgctaa
    31261 gagataaata tggaaaaaac aaagtacact tctttaataa ttacttaaga aaacaacata
    31321 gagaaaaatt agaagaatat ggaattaacc aaagtgaatg gaaagaaatt attataaaac
    31381 ttaatagtaa taacaaagaa ggtggactat cagactttgt taaagaacat aatacttcag
    31441 aaaaacttat aagagataaa atattacctt taatagagac aagcttaaca acagaagaat
    31501 tcgctccaat attgcaaatt aaggaacaag taagaaagtg tataaataat attatagaca
    31561 tgaatgaaaa attatcagat tataaaaact atagagattt aaacattaga gttgaaagtt
    31621 tacaaaataa aataaatagg atcctattca tagaagaaga taaaaataat gtattaggag
    31681 aattagctaa tctatatgta catatagaaa ataaacgcaa tgaattaaat gaagaaataa
    31741 aacagtatca aaaaatgaaa gcatcaaaag aagaggaatt taagatagta gaatatgaag
    31801 aagatagcta tgagtatttt agaaaagaaa aagagataca agatactcag gtagaatttg
    31861 ataaagccaa aaatgaatta aatgataaaa tagaagaact agaattagat gaacaatatt
    31921 taaatatatc aaagttcaaa agaaaaaaga aggggctaga agaaggggaa aaagataaga
    31981 tagaaaaaga aagtgaaaaa caaagaaaag aggtaaatca agaagaaata acggctatta
    32041 taaatcgtct aggtagcagt attcattatt gtttaaagga agaaagtatt ataaataatg
    32101 aaaaacttaa agaaaataca aacaacaata tagctataca agaaaaaaag aatcaactta
    32161 atgatgacaa aagtaagctc acaaaagtat tgataagtaa aaattcagaa attaaatata
    32221 tagaaggcaa agaacgtgat tttaataatc aactacatga atttaaactt aataacactg
    32281 atattaaagg ctttatttct aataattttt taggcgaagt aatagattat actaggtata
    32341 taaattattt aaatataaaa gtaaaatcaa tagaagaaaa tcttgaatcg aaagtcatgc
    32401 aaatagaaga atcgaataaa cttaaggatg atataaatga agctataaat aatcttaaat
    32461 tagataatca tgaatcttat atgaaactgc aagtattaaa aactagaaag aaagatatag
    32521 ataattttaa agaaaaatat aaaatcatta aaacaagatt tgaaatagac aatgaattag
    32581 ataactctac taaactatat aaagaggtaa aacaagagct taacaaaatg aaacttcaag
    32641 tacaggactt agaaaataat aaaaagcaat tagaaaaaga gctagaagat ttacaaaatt
    32701 ataaagatat aattttcgaa gaagaaatat taacagatct agaaagaaat ggaataaaac
    32761 ctattgaagg catgaaatat ctattaacct tagatggaga tttagaatac aaaaataatc
    32821 tcatatctaa aaatccattg ctaccatatt ctataataat tacaaataaa gagtatcaaa
    32881 aactgaagca aataaactta aaaaataaaa ctaaaatctc aatgcctata tttgtaagag
    32941 ataacataga agatactttt ataactacat ctagtaacct tgtaattagt aatggattaa
    33001 atatactatc ttctttcgat aacaaagctt tagatcctga aaaaagagaa aaggatatga
    33061 atctaatcaa agaacaaata aatagtattc gagataaagt ggagcaatat aaagcagaaa
    33121 ttgaaatatt agaagaattt aaacttctaa ctaataaaat tgattttaca gctgaagact
    33181 tatccataga tgtgaaaatt gaaaattata aaaaaattat atttgaaata aacaataaaa
    33241 ttaagagtaa tgaaaataat gagaagaatt tatctaataa aattaaagaa ctttacgaaa
    33301 ataaagaaaa gctattaaat aacaagaata tattatttaa taaattgaag gacattagaa
    33361 atatacaaga tacatattct ataattttag aaaataaaaa tgaaataact aagttaaaaa
    33421 caagtattga aaaaatcgaa gaagaaaaaa aagttattaa aaaatcaata gaagatattg
    33481 atgttaatat atttaattta aattcagaaa aagataggat aaataggcat atagatgata
    33541 cagaaagcaa gataaataaa tttaagattt atgaacctat taaacttgaa aatgctaaac
    33601 tagaagaatt agaaataaaa tacaagaaat acttagaaga ccctacaaaa aaagagattg
    33661 aaacattaaa ttatgaaatc tcagtttgct taaaaagaat agagagtatt actatagagt
    33721 tagaagaatt tagacaactt attagtagtg ataattttga aaatatacct atattattca
    33781 caatagaaga acttaataaa agaatagttt taaataaaag taaggttgat gaactacgaa
    33841 aacttaaata tagtattaaa agcgacatag ataaaaatca aggttcatta aacactaaga
    33901 gggaggagat acttaaaaaa tttaatggaa aagaaccttt atctactagc ttaatagtga
    33961 actttaattt tgaagaaaga aaaatagata taaaaaaaga tataaaggat attggtgaaa
    34021 ttatagaagg taatagaact acttgtcaaa atctagaaca ggaattaaga gacttaaaga
    34081 aatataaagt agaaagaaaa gctataacct atcaacctga agatattttt attgaaagta
    34141 aaaaactaca atcaaaactg caaaatgttg aatataattt aattaaatct ataaatagct
    34201 ataaaaatac aatattagaa ataaaagaat ttaattataa gcacatggaa aaatacaaaa
    34261 actttataga aactttaaat gtaaataaag ataattactc tcgacaaaaa gaacaagtag
    34321 aaatagtatt actagttata agagaagaaa taagcaaatt agaaaaacat agcgaacaac
    34381 taagaaaaga aaagactata atatcaaggc aaataaaaga ttatgttatg gactgtattg
    34441 atgaatttaa aatcataaat aaacttggta aacataaagg acaagcctta ttcaacatat
    34501 cactacctaa atctgataaa atagaaaata gtttgagctt agtagatatg ctaatggatg
    34561 aaattgtaga agaagcaaac ctaggtgatg ttgaacaaaa aataaatacc ttttatattt
    34621 taaataagac tcttaatata gggagaattc ctgtatcagt tataaaatat gaaataaata
    34681 gaaatgaaac tataaagtgg aactctatta ataacgaaac aacaggagga cagagatttt
    34741 gtatctcatt tattgtgaca atattgttga tggaatataa aagatatgat agaaatgcaa
    34801 tagttgatga aagtaaatat aagggtaagg tactacttat ggataatcct tttggagaaa
    34861 cgtcgcagca agatttcctt aaagaaatat ttgaacttgc taaaaaattc aacgttcaaa
    34921 ttatatccta tactcatgta acaaatgctt ctataagagc aatgtttaat aagatttatt
    34981 taatgacagt tgaaaaaact acttctaata aagaatttgt ggatattaat gagattaagc
    35041 aaaataaaac tgatgaattg gtgtatatga gtaaatttta tataggtaat aaagaagaat
    35101 taattcaaga ggatatattt agtttaatat aaataacaag taaacaaata aagtgattac
    35161 tatcagtgag gcaggtagaa actgaattac tttgtgactc attacgactc ttggggtaaa
    35221 attgtgtata aatgtgaaga atttcgtgat tgtcagtaca aaagcagctt tattaagggt
    35281 aataatagta agactcctct tgaaaatagg actaaaaact tacaagtatc taagttattt
    35341 catgaaaaaa gaaaaattaa agagaattat aagaccagag ggatgtgaac ttagagtgaa
    35401 tagaagtata caagtagaaa gagctatcgc agaacaaatt taattttatc atacgatagc
    35461 ctcttgttat tttagtgatg aaatccatca agcataccat aactacagaa aaagaggctt
    35521 ttctgatggt atattgggtt cttttagagt gtgtgatttg ctacatgttc attaggataa
    35581 taatagtcag taaatgatat tactgataga atagatataa taaactaatc tagttccata
    35641 ttgtaatgtt tattaaagag tatactttta tgattataat agctattttc tttgaagctt
    35701 attgtacaag agatttgaat atatcaaatt tggatatagg tataattctc ttagcagttt
    35761 tatttataca gtctttatct aaattagtgt tgtatatact ttgataaaag ggggatatgt
    35821 aactaagttg taatattgat gaaaataaaa attaaaaaat atagagaaaa actccttatg
    35881 atacaaaatg aacttgctaa atcagttggg gtaagacgag agactattgt acacttagaa
    35941 aatggattaa tgtaccataa aggtatccaa gataaatagt taaaaaacta gataagaata
    36001 aggagccttt acagaacaaa tttagtgtgc tcgtgcgata gccctttttt tataaaaatt
    36061 aatctaataa cctatataat taaatttata aaacatatat gaaagggtaa aactatatgg
    36121 ctaaaattga taatatgatg tccatattat ggatgttaaa ctcagacaaa aaagttaccg
    36181 caaaacaaat atctgaaaaa ctagaaataa atataagaac tgtctacaga cacattgatg
    36241 cattatctgc tagtggagta cctataattt cagatacagg tcataatggt ggatatacac
    36301 ttttgaataa tttcatcaaa gcacctcttt ttttcgatac agaagaacaa actgcgttac
    36361 ttcatgcagc tatatttgct aaagaagagg gaagtttctt agatgacaca ctagacaaag
    36421 caacctcaaa gttaaaaatg tattcaaatc aaaaacaaga agaaacttta acaaaacatt
    36481 taataggttt tgaagtaata aaaccaactg gaaaaatatc catagaatct gtacttaaaa
    36541 agttaaaaaa tagtatagca aatgaattat ctgtagaaat caactatcgt acagctcatg
    36601 aagaaaaatc aaaatgtagg attataaatc catatggaat tgtacgttgg aataataatt
    36661 ggtacatagt agcattttgt caaatgagaa atgagattcg tagttttagg gtagatagaa
    36721 ttagtagtgt catagaaaca tcaaatactt ttaataggcc aaaagaattt tcagcaagtg
    36781 aattttttat aagagggatt atggatgaaa caaaagatga ggataatctt atatcattag
    36841 ttatagaagg aaagatgaat gcattggata acttatgtca gcattggctt ctaggatatt
    36901 atttaaaaga aaggacttca aataaagcaa tatttaaact tcaagaagag ataatattta
    36961 catatgtacc gaatatactt ataccttata gaaaatctat acaaataatt gaaccattaa
    37021 gccttaggga taaaatggtt gaagatttac tcgaattaat taatcattat caaatttaat
    37081 aacttaactg acagagtatg tcagttaagt tattttacaa ttaggtatat taattaatta
    37141 tagaaggagc aaaaaaatga aaaagagaaa agtatatatg tatgtattcg atactatgtc
    37201 agattgggaa gttggatatc taactgctga attaaataca ggaagatatt ttaaaaaagg
    37261 attaaaacca ctaaaagtaa ttacagtagg agttgataaa aatcctatta taacaatggg
    37321 tggattaaaa gttttacctg agattacaat tgacgagctt aatattgaaa gtaatgactt
    37381 attaattttg ccagggggaa atacttggac atctataggt catgagaaaa tattagaaaa
    37441 atctaaagag gctttggaac aaaggtctat agttgcagct atttgtggtg ctactttagg
    37501 gttagctaaa acaggtttac tagattttag aaatcataca agtaatgatt tagaattttt
    37561 aaaaatggtg atactaagtt attctggaga aaaatattat aaaatggaat ctgcggttaa
    37621 tgatgaaaat ttaattactg cttctggaat tgcaccatta gaatttacag tacaagtttt
    37681 aaaagtttta gatgttttta aagaagaagc attaagttct tggttgaacc tttataagac
    37741 gcatgactct aaatattttt tcgaactaat gaattgtaat aaataaattt aagatttaat
    37801 tttaaattca aattttaaat tactttttct atggcaatag ataagtagtt tagaatttta
    37861 tcatatatat aatttgtatt tataccaaca caaatagaaa tgatagttcc aataataaaa
    37921 tttataatta gttccatatg gagtacattt ctttcctact aatataacta agaatatatg
    37981 aaaccaccat agattgtagt tttttctgtt gtattatatc atgggatagt aaagtgacgt
    38041 atatttttga tgaaaaccta ggattgtata tgaaatgaat taatcctgtg tattaatctt
    38101 gagattcgtg tctaatgatt tgtaaaaata aataatgaaa tacttagaaa tacttgtaaa
    38161 tgctagtcaa tattggctag tattttttat tttagtaatg aaatccccaa ctgtacttca
    38221 tccacaaaaa aagagatatt tttgagggtg tattggagtg aacttaggct gtataattat
    38281 acatttcaat atcttatatt aattaggata atagttggta aatgatatga ttgaaacaat
    38341 agatataata aactaatcta gtactgtact gcttactaaa gaatatattt ttatggtata
    38401 agaatttttt agagcgttga ttctatagga gtgaataaaa aagtaatttt ataatattat
    38461 ttgtaaccat tagatgtcta ttatgaaatc ttttatggac tatatttgta aaaatattat
    38521 taagtattta caatattttc ttgcaattta tttggaaagg ttatatattt ataacatgaa
    38581 gtgttataaa tatataacct ttaaggtgga ttttatatgt ctaaatcaga aactggtgta
    38641 aaatcaaaac tcatattgga attacttgta ataacttatc tttttatagc tgtattagct
    38701 actaagtata tttttaaagg tccaagtact gcatctcttc caggactgag ctggttaata
    38761 gtctttggat gctattcaat ttataataaa aaatataatg atttagttga tgaatcatct
    38821 aaatttatac tatcaaaggt taatcagatt gcaataacaa taatgatgta ttctatagtt
    38881 ataatagcta ttttctttgc aacaccttat ataagtaata taaatatatc aaacttggat
    38941 actggtataa ttcttattgc agttttattt atacaatcgt tatctaaatt aattttgtat
    39001 atatactttg ataaaagggg gatatgtaac taagtggcaa tatcgatgaa aacaaaaatt
    39061 aaagaatata gagaaaaact ccttatgaca caaaacgaac ttgctaaatc agttggggta
    39121 agacgtgaga ctattgtaca cttagaaaat ggaaaatata atccttcttt aaagttagcg
    39181 atggatattg ctaaagtatt cgggaccaca gtagaaaatt tgtttgaatt tattgaagaa
    39241 gattagtaga taggatataa atatttataa gattgttaat aaaatatagt tatttaatta
    39301 ttaattttgt taaaaatatt tataaataat ataatgtatg agtaaagtta ggttgtaatt
    39361 attttaagat aagaagacta ctgtaaatga taaaaattag tgaatataca gccaattaat
    39421 aaataataga taaaacttta aagcttagat gtgaggatga gatatggtct tacagtagtt
    39481 cacactttta attaagactt aaaatggaaa ccatacacat acatacacta tttactgaaa
    39541 gtggactaga taaaaaaata ataagtgatt taagaaagta tctcatatac tatataagta
    39601 ttattttagg tgacctattt ataggtcatt ttttatgtat ataaatgata ataatactaa
    39661 tatttaaaat aggttttaaa gaaataaaat atccagattg aaaaatggat taatgttaat
    39721 aaaaaaatta tatgtataaa aataggtata attatagaaa aaaacaataa taaaataagc
    39781 tgttatagaa aaatacaatt atatagattg ttgttgaatc attgactgca agaataataa
    39841 catttaaaat gaacatggag aatatggggg aggaatcaat atgaagagaa aaatagcagt
    39901 tgttttatta actgtagcaa tgttattatc acttgtagct tgtagcaatg ataacacatc
    39961 aaaaagtgat aaattagagg atacattagt agtatatact acacatggag aggatatgct
    40021 aggagcaatt tctgaagaat ttacaaagga aacaggagtt aatgttgaat ttataaactt
    40081 aaaaggtgaa ctagcagacc gtgttagaag tgaaaaagat aatccgcaag cagatataat
    40141 gtttggtgga gatacatcta catacatgca attaaaagaa gaaggattat atgaaaagac
    40201 tgaaccaagc tggaataatg aattagacaa gtcttacaaa gattcagatg gatattggta
    40261 tggaactata aaaacaccag taatgatgtt ttataacaca aaactattat cagctgataa
    40321 agcgccaaaa gattggagtg atttaacaaa agaagaatac aaagacttaa tagttactag
    40381 agattcatta tcatcatcta tgcgttctac tattagtaac ttaatcaatt actactcaaa
    40441 tactaagagt gaagaagaag cttggaagta tcttgaggat ttaaataaga atataaagaa
    40501 ttactacaat agtggaagtg tcatgtattc agcaataggt aaaggtgaag ctacaatatc
    40561 tgttgcagta ttaagtgata taatagagaa taaagaaaaa aataatatgc cattagaagt
    40621 tgtagatgca gagagcggtt ctgtagtaat cacagactgt gtagcagctc taaaaaatgc
    40681 accacatcca aatgcagcag ctaaatttgt agattttgtt ggaagtgcta aggttcaagc
    40741 tatggttgca aatgatttta atcgtattcc aacattagat tctgcactta aagattcacc
    40801 aaagtggatg tcaaaagaat ataaagctat ggatgtagat tggtctgtaa ttggaaaaaa
    40861 tcagtctaac tggattgaaa agtgggaaac agatataata gataacaata aaactataaa
    40921 atagcctaat taaataattt aatattatat acaaaaatag tgaggatttt cctcgctatt
    40981 ttacgtataa ggaaactata gtatctcata attttgtata attcatacaa caaaatgata
    41041 ctaatacata cttattaaat aaaatagttt ttgagtaact gatgaagtaa ttgactatat
    41101 aaagtgattt gtagacatag tctctcaaat aaagtgaatt ttttattatg caaaactttt
    41161 aattatagta aaagtacaat ttatatgggc aaggagataa aaatggaact aaaaattagt
    41221 gattataaat tattatgtaa taaaggtagt ggcgctttta acgaagatat cgtaggttta
    41281 tcaccttatg gggcatgggt acttgatgga gctacaggtt taaataataa aaatttagtc
    41341 tctacagaaa gtgatgccaa atggtatgta agttggtgga atagttatct tcatgagaat
    41401 atggaaagag aagatagctt aaaagtaatt attaaagaag gcattgagga gataacaaaa
    41461 gagtactaca aattaacaga tgataaagaa gtagaagcaa tagatattcc ttcttgttca
    41521 tgttctatat taaagtttta taaagataag atagagtatt tacttttagg agattgtact
    41581 ttattagtta acaataatga atctgtgaaa attttaaaag atgagacttt atgtgaactt
    41641 gataaaaaag tatttgattt tatgaaagaa gccaaagatg ctacaaacct tactttaaag
    41701 gagagaaaag ccgaggtaat gcgattataa tagagaatag acttaagaaa aatactgtgg
    41761 ggggatattg gactttggaa ttttctaaag aggccgttga caattgtgta agtggattta
    41821 ttgatataga atataaaatg aaaattatga tggctagtga tggtttttca tgtggatatg
    41881 atagatataa gatttttgat aaaaatgaaa tgatgaaaat agcagagatt aaaggtatag
    41941 attatatata tagaaaggtt agggaactag aaaaggatga tgaaatggca atagagtttc
    42001 ctagatttaa aatctatgat gattcatcat gtgtatattt agagatttat aaatattaga
    42061 taatttatgg agacgatatg aagaatatag aattaaaaga aattaatcat tattatggaa
    42121 aagaaaaagt attacatgat attaatatat ctattaagga aggagagttt tttactttac
    42181 taggtccttc tggatgtgga aaaacgacta ttttaagaat aattggtgga tttataaaac
    42241 cttcttctgg aagtatttat gttggtgata aaaacattac caatttagaa ccagaaaata
    42301 gaaatatggg aactgttttt caaaactatg cactgtttcc aaatatgaca gttgaagaaa
    42361 atgtatctta tggattgaaa ataaaaaagc tgtctaaaaa aattataaag gaaaaatgtg
    42421 ataattattt agagctgtca ggaatgaaag attttaggaa aaaaaagatt gatgaattat
    42481 ctggtggaca gcaacaaagg gtggcagtag caaggtcatt agcgactgag cctactatgc
    42541 ttttattaga tgagccaatg tctaatctag atatagcttt aagaatcaag atgagagaag
    42601 aaataagaga gatacagcaa aagacaggta ttactacttt atttattacc catgatcaac
    42661 aagaagcctt agctatttct gatagaatcg ctgtaatgga taagggtaaa gttcttcaaa
    42721 ttggtgtgcc aatagaagtt tacaaaagcc cattgaatga ttttgtagca aactttgtag
    42781 gtacttcaaa ctgtattgga aaagaagatt atgttaattt taatattgaa aaagagacaa
    42841 agccttatat ttataaaaga cctgaagaaa tgatattatt gcaaaataca aatcaaagtg
    42901 gttttgtaaa agtaaaagta gaatctaaga attttctagg agcaatttta gaatatacag
    42961 tatcaaatga tgggaaaaaa tatcaagtaa ctgagcttaa tagactgaat aatagcaata
    43021 aattaaacgt aggggatatg gcatatttag gtgtgctaca aggtgactaa tatgattaaa
    43081 aaaataaacc gtagtaaatt tacatctaaa aatgttattt ttattgtttt atacagtata
    43141 ttattttgga ttttgattgg atatattatc ataccaatag gcaatacttt tgtacaagca
    43201 ttccaaggta aaggtggata ttcttttgaa gtttttaaag aatatttttc aaatactaat
    43261 aatttaaggg tagtaagcaa tactataatt ttgggattgg gttctgtgtt cgtatgtgga
    43321 attatgggaa tatcacttgc cttatatatg acatttgttt gtgataaaca taagaaaatc
    43381 atacatattc ttttactaag tccaatgatg attcctggag taattatggt aattgcatgt
    43441 attcagattt atggagaaag tggaatagtt acaaaatcta tagaaatttt actccccttt
    43501 atcaaaaaac cttatgattt tagtggatta aagggaattt tatttgtggt tgcttatact
    43561 cagtatgtat atttttattt aaatgtatat gttgccttaa aatatgtgga ttactcaaca
    43621 gttgaagctg caaaaggaat gggagcatca aagctaagag tattttttga tgtaatatgg
    43681 cctgttatta cacctgctgt tataacttct actattataa cttttgcatc agggattagt
    43741 tctttctcag ctccaaatct tataggtggt ggttttaaag ttttaagcac tcaaattgtt
    43801 aggtctaagg ctaataacca tatggatata gcttcagttc aagtaattac tttattacta
    43861 atggggattt tatttatgat tttattacag tattatggca aaaaatatgg agtagtgcca
    43921 tccttaaaat ctcaaagtta taaagttcat aatagaaaaa aagacttatt tacatttgta
    43981 tgtaaggtta ttattgaaat acaaattatt atgattatgc ttcctatagt tactattgtg
    44041 tatttatcct ttgtaagcac acattcaatt atgacaacca tatttcctag agactttaca
    44101 ctggaaaact atcagatgat tttccaaaaa tcacgtgtat tacagcctat attaaatagt
    44161 ttcaaaatgt ctttaatggc agtagcagta ggattgataa ttactgtacc agtatcatat
    44221 ttagtaatta aaaaggatac tgcatataat cgactagcaa aatttattat aatgttacct
    44281 tggagtatgc ctgcaagcgc cattgcagtt aacctaatta atacatttaa tcaaaaaagt
    44341 atatttgctt ttaatgaatc cttaatagga ggtttttata ttgtacctat agcatataca
    44401 atttatgctc taccattatt attttcatcc aatgaggttg ctatgaagtc aataaattta
    44461 ggactagaag aatcatcaag gagtttaggt gctggaagga taaaaacctt ttataatgta
    44521 atagttccaa atatgatgcc aggaataatt tcaggagcta tattagtatt cattcgtaca
    44581 attggggaat atacaatgtc agccttgctt tatggtgttt ataatagacc tatttcaatt
    44641 tctattgtaa ctaatatgca agaatttaag ataggagtat ctatggctta tggtgtatta
    44701 gtaattggta tatgctatat agcattagga ataattttta aattagatag aaaaagattt
    44761 acataagata acaaaggcta atttataaat tggtgcttag aaaaccaaat cactttatta
    44821 gctaaagatg aatttgaagg gtgacacttt ggtgttttat gtaaagttta tggaagtaaa
    44881 acattaaata atcgtgagta tgattcctat aaatcgtata tactattgaa atccaagaaa
    44941 aggtattggc taaatagcta atatcttttt aattttttga ctcccatata gcattaacta
    45001 ttacatgagt atctttaaat ttatagttaa agtatcttaa ttgtttatta taaaaatata
    45061 ggatggctaa agcacattaa attaaaacac ttaaaaagag aagatgtaca tgagaaatat
    45121 aattaactat gatacagact tctaaaaatt atttagtgaa aaggaactta gagtgtataa
    45181 taaaagttcc ttttcaataa ggaaaacgat tgttattttc tgagcttcat taccctgata
    45241 ttatttaaat ataaacaaca acaaaattaa caagaagtaa attcaaccta aaatttaaaa
    45301 tatcgggagg tacaatatgt taatcaatat gaaggaaatg ctaaaagtgg cacaagaaaa
    45361 tcaatttgct gtaccagcat ttaatatagg aagtgggcaa atacttaaag cagtagtaca
    45421 gggtgctaac gaaaaaaatg caccagtaat acttgcaata cacccaaatg agctaagttt
    45481 tctaggcgat agctttgtag ttagttgcat agaagaagca aataagagta aagtacctat
    45541 ggtaatacac ttagatcatg gggaaaataa agaacaaata ttaagggcaa taagatgtgg
    45601 atttacatca gtaatgattg atggctcaca tttaccatat gaagagaatg tagctatatc
    45661 tagggaaata gtagaaatag caaaaggatt aaatgtgtcc gtagaaggag aacttggaac
    45721 aataggaaca acaggaacat caagtgaagg tggtactgat gaaataatat atacagattc
    45781 aaaattagct aaggattttg ttgaaaaaac aggagtagac acactagcta ttgcaattgg
    45841 tacagcacat ggtatatatc caaaaggttt taaaccagag cttaaactag atttattaaa
    45901 agaaataaga gaagtagtag atataccttt agttcttcat ggtggttcat caaatccaga
    45961 tgaagaaata gcacaagcag ttaaactagg agtttgtaaa ataaatattt cgagtgatgt
    46021 taagtcggca tattataaga agtgcagaga actattagaa caaaacccaa gcttatatga
    46081 gccagatact atatatccac catgtataaa agctgcaaga gaagttatag agtttaaaat
    46141 gaatctattc aatgctatag ataagttaaa gtgcttttat aaaaataaaa attaattatg
    46201 aggtaacaaa ttaaaaggag gggagaattt atgataggta aaatactacg aagcgattgt
    46261 attgtactag ataaacaatt acaaacaaaa aaagatgtaa ttaattatat ggcaaatcat
    46321 ttgtaccatg gaaattatat aaataataaa gaaaagttta tagctgatat taataaacgt
    46381 gaaaaagaat catcaactaa tatgggtaat ttaatagcta tacctcatgc taagtcaaat
    46441 gtagtaaatc aacctgtaat gatgtattta agaacagata gagagattac agataatgat
    46501 ggtcaaaaac ttaggtcatt ttttatgata gcagttccag aatcaggttc agatgaacat
    46561 cttaagatta tatctaaact agctacatat ctaatggaag aaaattttct taagcatcta
    46621 ctaagtgcag aaactccata cgaaatatta agtatattta ataataaagc tgcagaatca
    46681 ggagatttta gtaataatca aaataaaggt cttatagttg ggataacagg atgtccaaca
    46741 ggtatagctc atacttttat ggcaaaaaaa gcattagagg aagcagggca agaacttgga
    46801 tatgaagtta aaatagaaac tcatggagct ataggtgtag aaaataagtt gactaaagaa
    46861 gatataaaaa gagctgaata cgtaataata gcttgtgata aagaagttca actgagtaga
    46921 tttataggaa agaaagtgct acaaaagaaa gtagtagatg ctaagaatgt ttcattagct
    46981 aaaaatttaa ttataaacgc tgaaaatgga atggctaaag aaattaaacc aggtggaaag
    47041 actttagaag attcaaaaga aatgcttcaa gggtcagaga caaagggtgt ttataagcac
    47101 ttaatgagtg gtgtatctga aatgattcca tttgtagtga taggtggaat tggtatagcc
    47161 atagcattta tgtttggtat atttgcatca gacccaactc atgaaacata caaccctata
    47221 gctggattct ttggacaact tggaggcgat tcagcattta agttatttat accgatactt
    47281 gctggtttta tagctaaatc aatagcagga agacaaggat ttcctcctgc tatgatagct
    47341 ggttttatgg cagttattgg aggttcaggg tttataggtg gtatggtagc tggttttgca
    47401 acaggatata tagctttagg agtaatgaag ataacagaaa atttaccaga tgtattaaaa
    47461 ggagtaaatg ctgtattgat atgtccactt ttgattgcat ttacgagtgg agctataatg
    47521 ttctttgtag ttaatacgcc agcatcatgg ttaaatgaag ctttacaatc ttggttacaa
    47581 agtatgtctg gaactaataa agtattatta ggtgcaatat tagcagggat gatggcatca
    47641 gatatgggag gacctattaa taaaacagct tcagcttttg gattggctat gttttcaagt
    47701 aatatatttg agccatcagc agcattaatg gtaggaggaa tggtacctcc attagcgata
    47761 tcattagcta tgttaatatt caaaaataag tttactaaag aagaaagaaa gtcatctcta
    47821 ccaactgcta taatgggggc atctttcata acagaaggcg caataccgtt tgcagctgca
    47881 gacccattaa gaatgattcc agcaaatata attggttctt gtataggtgg ggcaatctgt
    47941 atgagtttag atataacttt aatggcacca catgggggaa tatttgtaat accatttgca
    48001 tgtagtgcac cagttgcata tatagcttgt atattgattg gtacagtaat aacagcattg
    48061 attatagggg tagcaaagcc tactataaga agtgaaaaca gtgaagttga attacttggt
    48121 gcttaaatta taaataatag taaaaataag taatggaata acaacaagta tatagaataa
    48181 taataaggat atttagaatc agttaactac ttctaaatat ccttaatttt tattttgaaa
    48241 ttatattatc tattatatca atttagtaag gtgtatcata aattctttta tgatacagaa
    48301 gtatcttagt aattttacat agttagtaaa tatgttaaaa tagtacttaa tataaacata
    48361 gaaatatata aacataggta gggagggcta agtatgcttg tgtcgaggca aattgaattt
    48421 cttaaattga tactaaacga aaataaatat agacctataa aatactttaa agataaatta
    48481 aatgtatctg ataaaacttt acaaaaagat ttgaagatga ttgagaaata tttagaaact
    48541 tttaatataa aaattgatat aaaaagaggc tatggaatat taatagaaga tttagcaaag
    48601 aagaacatag acttaattaa tagtttaaat atacaatcga aggaaaataa atctttatca
    48661 gtagagcaga gaagaatgga gattttaaag tatttattac taaattcaaa taatataact
    48721 tcaataaatc agttagcaga taaatattat gtaagtaaaa cttctatagt aaatgatttt
    48781 aaatatatag aggcatggat aaaagaatac aatttaaaac ttaataaaac tttagaagga
    48841 actaagatta taggtaaaga agtggatata aggaaatcga ttgccaaaat gatggatgat
    48901 ttattagatg aaaattatga acaacatgat atatctgagt taacaagatt agattctgct
    48961 acatttagtg cattgataaa tttatttgat attgattcta ttatatttgt agaaactata
    49021 attacagaat tagaatacaa tttaggatat actataaatc agccctacta tataaattta
    49081 attacccata tacttatatg tttaaagaga atcgaagaag gtaatcaaat agaatctcag
    49141 gaagaaagag aaatttctgt agataatttg gacgagttag tatataaaaa tgtcactaca
    49201 cttatagata aaatagaaaa tagatacaga gtaaaaataa cgaaagatga aattatgtac
    49261 atatatattt ttttggtatc atctggattt agtagcgaaa ataatagtag ttataatgat
    49321 gaatcagata tattaagtga aagtgaaaaa gtttcatcta taatgataga gaatatgtca
    49381 caatttttaa atataaatct caaaaatgat gacttactac aaaaaagtct agcatctcat
    49441 gtaaggccta tgttaaacag attaagatat gatatccaaa taaaaaaccc gttgttagga
    49501 gagatacaag agcgattttc agatgtgctg ggattatgta tgatgactat aaatattatg
    49561 acagagtatg ataatctgaa gaatattagt atagatgaag tttcgtatct tgccacatat
    49621 tttcaagcgg caatagaaag aaatatgagt agtaaaagag taatagtagt ttgtcataca
    49681 ggatatggaa catctcagct ccttgcagcc agattaaaaa gagaatttcc tgaatggact
    49741 atagttgata tagttcctat gcatcagttg agtaagcgaa atttagatga tgtagacttt
    49801 gtaatatcta ctgtaaactt agatttgaaa gataaattac atatagttgt atcagtacta
    49861 ttaatggaaa gtgatattaa taatataaaa aatgctttac tttctaaacc taaaaaaagt
    49921 atgaacttag atacaaactt attaggaatg tatttagaag ataatatata ttttaatttt
    49981 gatgtagctc agatggaaag tttaataggt gtgaatttag ggagtaaata tgaatctatt
    50041 tcattaggaa aagatttgaa tatatatata cataagcaaa gtaaattaaa taaagggata
    50101 atgaatatca ataatgttac tagaacgatt gatatttatt tagaaattag taatcaaagt
    50161 tttttaaaga atattttaat ggaaatatca aatttatata ggcaaaagaa ctatataaac
    50221 tatataatag attgcaagag caaagaggat attaaaatat tatttaagaa taatctattg
    50281 gagaaaacaa atggaaatta gagaaatatt aacagaagaa agcattattt tagatttgaa
    50341 atcaactaca aaagaaggca taatacagga attagtagat aaattatacg atacaggaag
    50401 tataacttta aaaagtaagt ttataaaggc attaaaacat agagaaaaaa taggctctac
    50461 tagtataggt tatcaaatgg ccatgccaca tggaaaaaca aaatatgtaa agaaggcatc
    50521 catagtaata ggtaaatcta aaaaaggtgt agattggcca agtatagatg gcttacctgt
    50581 aaaggtaata attatgtttg ctatgccaca atctggaggc aatgaagata tgatattaat
    50641 atctaaaata gcttacattt taggtggtaa aaatataagt gaaagacttt taaatgtaca
    50701 tacaaaaaaa gaaatattag atatatttta tgaagtgtag gtattgtata aattataaat
    50761 ttgaggtttt taaaataaaa tgtgtattct tttaaatagt atagattaat ttttagacac
    50821 tagagaggag aggatatcta tggcaatata tttagaaatg cctaaattaa tacatgaatt
    50881 tccttttcgt agtctatcaa atgaaggaga agtattaaca acaccacact ggcataagga
    50941 aatagaaata ttacttataa cagaaggtgt agtaaatcta tttataaatg acaagcctat
    51001 gcaattaaaa aaaggcgaga tagtgataat aaaaggagga gatattcatt atatactgcc
    51061 atcaccggga agtgaaagat tagtatttca atttgatata tcttttttta atgatttaat
    51121 tttattaaat gaggaaaaag aaagcttaat taatttattc agtagtataa aaaaatgtag
    51181 tagagattgg tcagcaaaaa taagaaagtc agttttcgat atattgatag atatctacaa
    51241 tgaagaccta tacaaaatag aaggatatag ttatgcaata aaaggtaaaa tgtataattt
    51301 aattcctata ttatatagac agattcctag agaaattgaa gaaaatacag tagaatatga
    51361 aataaactct aaagagatat tagagagatt gaacaatata ttcaaatatg tagaaaaaaa
    51421 ttataaacaa cctataaaat tagaagatgt gtcttatgaa gtaggattta gtgtatatta
    51481 ttttactaaa tttttcaaaa aaaatacagg aaaaacattt ataacttttt taaatgaata
    51541 tagattagaa aaagcaaagt ggatattact taataacaat atatccattg tagatttggt
    51601 tgaagaagtt ggttttggaa gtacaaaaac tttttacaga gtatttaaag aaaaaattgg
    51661 agtctctcca ttagaattta aaaaaagata taatagcttg gagaaaaaag ggggtgcctc
    51721 aaaatgaact tagttcatga ggcactttct tttatatgaa atcaaatata ttttcagtat
    51781 ttcaacaatg aaaattccat tcatttataa agtctaaatt ttagttctca atacaatctc
    51841 tatttcgaaa taaatccttt tatatatata aatatacagc aatatatgag aataagataa
    51901 caataatgag gatataaaaa tgtatttgct atatatataa ttatatacat agatatctaa
    51961 tattgatatt taatatgaaa gtattgaaaa tagacaatat taattatagt gagtaaaaaa
    52021 tataattgga tttttaaatt gaattattta aaaggtatag tatgaaaaaa atcttataac
    52081 taaatatgag atagaaatta taaaacttta tactgtgaaa gaggtagatg catgaaatta
    52141 gggaaagatt ttttatgggg aggggcaatt tcagccaatc aaagtgaagg attttattta
    52201 gatggaggaa aaggtttatc tcagtttgat aaactcccat taaatgataa gagattaaaa
    52261 gatgtatgtt tagatgagga taatatttta aatgaaaata atcaatacta tccaagtcat
    52321 atagggatta aattttgtga aaattacaaa gaagatatag caatgttagc agaaataggt
    52381 tttaaatgtt ttagattttc tatatcttgg tcaagaatat tcccaacagg agaagaaagt
    52441 gaaccaaatg aaaagggatt acaactttat gataatataa taaaagaatt aaaaaaatat
    52501 aatatagagc cattaataac gataagccac tttgatatac cttattctct agttgaaaaa
    52561 tattctgggt gggctgatag gagagtggtt aatttatatg taaaatatgc tgaaattttg
    52621 atgaaaagat ataaagatga tgtcaaatac tggattcctt ttaacgaaat gaatatgata
    52681 attcatattc catatatagg tgctgggtta acttttatag ctgatgaaaa tcaacttcag
    52741 aaaaaatatc aagcagcaca ccatcaatta ttagctaatg caaaaactat agaaatagga
    52801 aggtatataa ataaagaatt taagtttggg tgtatgttag ctgctggaaa aacatatcca
    52861 tacacatgta aaccagaaga tgtatttgca actttagagc atgaaaggca taatttgttt
    52921 ttttctgatg ttcaagttag gggtgtgtat ccaagcttta tgaattatta tttaaaatca
    52981 aatcaaataa aattaataat aaaagaggaa gatttatcaa cacttaagga taatactgta
    53041 gattttgtat cttttagcta ttattctagt gcttgtagtt cagctagagc tgaaggttta
    53101 gaaaaatcaa aggcaaacgg accagaaacc ataaaaaatc catatcttcc aaaatcaaat
    53161 agtgtatggc aaaacgaccc tgtagggtta agaataacta tgaatcagtt atatgaaagg
    53221 tatcagttac ctttatttat agtagaaaat ggactgggta ctcaagatat tgtaaatgaa
    53281 gatggaaaaa taattgatga ttatcgtata gattacatga aagaacatat taaaaatatg
    53341 attcttggag taaatgaaga tggaatagag cttataggat atcttatgtg gggatgtata
    53401 gatgtaacca gtgtaagtga aggaaagatg acaaaacgat atggcataat tcatgttgat
    53461 tctgatgact atggaagagg ctcatttaaa agaactaaaa aacaaagtgc tttttggtat
    53521 aaaaaagtaa tagaaacaga tggagaaatt ttatttaatg atatggaaac tcatgcataa
    53581 ttcattttaa gaaaggagtg ttattatgag tttaatattt actactaagg accaacttat
    53641 agagcaaggg tttagtaagg atacaataaa atccaatgaa acgttgttta cactagctaa
    53701 tggacattta ggagttagag ggaatattga agagtccgat tttaataatg agtatgtaga
    53761 taatatgggt acatatgtaa atggatttta tgaagaatct ccaattacat atggagaaag
    53821 cgcttatggc tatgcaaaac aaaatcagac tatctgtaag ttacctaatg ctcatatagt
    53881 aaatttctct attgaaggag attgctttga tttatcaaaa ggtattacaa gtgaacatac
    53941 taggatacta gatttaaatg aaggaattgt taaacgttca tttatatggg aaaactctcg
    54001 tggtagaaaa gttaaagtat ctatagaaag attagtatca caagatatag aagaattaat
    54061 gatgatttca tatacaataa caccattgaa ttttaatgga aaaataaaat ttaaaaataa
    54121 aatggaaaat agtatggaga agtttaattg tgaaaaagta gatgacccaa gagtggcatc
    54181 tataaataag aagcaattta aaattaatgt aaaaaaatat aacaataagt attttatgaa
    54241 tttagttaca gaaagaagta gattagggtt atggtgtggg tttgattcat atattacttg
    54301 tggaaatatt acaaatgaga cctataatgt ttcagatgaa tgtattgagc gagaaataga
    54361 agtctatgcc aaaaaagatg aaaggttaaa tttagaaatt gttgtaggct atagtagagt
    54421 atattctgat ttaaatctaa atgaagaacg tttaaaatca ttagaatgtc tggagtcgtt
    54481 aaaatgttta gaatcagaag cacatttaaa atcattagaa ttggttttaa gagaagcatg
    54541 taatattgga tttgataaag tcaaaaatat tcagagaaag aaaatgaatg agttttggac
    54601 aacctctgat gtagagattg aaggcgataa aactcttcaa ctgggtataa aaaccaattt
    54661 atttcatatt tatcaatcag caggaagaga tggaaagact aatatatcag caaaaggtct
    54721 tacaggtgat ggctatgagg ggcattattt ctgggataca gaaatgtata tattaccatt
    54781 ttttatatat actcaaccat ccattgctag agctttatta gattatagat actcaatctt
    54841 agatgcatca agagaaagag ctagggaact tggaataaat aaaggttgct tatattcatg
    54901 gagaactata aatggtaatg aatgcagtgc atattatcca gcaggaacag cacagtttca
    54961 tataaatgca gatatagctt atggtattag aacgtatttt gaagcaacta atgatgaaga
    55021 atttatgatg caaaatggct tagaaattct tatagaaaca gcaagatttt gggttgaatt
    55081 tggagattat atagaattaa aaaataataa attctgtata aatggagtaa caggaccaga
    55141 tgaatataca gcaatagtaa acaataatta ctacactaat ttaatggcta aatataattt
    55201 aatatatgca gtacagatgg tagataaatt taagcataat ttattttcaa atgaagtatt
    55261 tagaaaagtt aaattacaag aatatgaagt aaaagactgg ataaatgccg ctcaaaatat
    55321 ttatttacca tatgatgaag agaagaaaat aagcaaacaa gacgattcat ttttagaaaa
    55381 atcagtatgg gattttaaaa atacaccaaa agaaaaatat ccattacttc tcaattatca
    55441 tccattaaca atatatagat atcaagtaaa taaacaagca gatactgtac tttcagcgtt
    55501 gcttttccct gatgagttta gcttagaaca aaagaagaga gattttgaat actatgaaaa
    55561 aataactact catgattcat ctttgtcaag gtcaatattt ggaatgatgg caagtgaaat
    55621 tggaaatcat gaaaaagctt ataactattt tatggacaca gcattaatgg atattaataa
    55681 cctacaaaaa aatacaagtg atggaataca tgctgctaat atgggtggaa catggatgag
    55741 tttagtatat ggatttgcag gaatgaaaat aaaaaaggat aaattaagtt ttgaaccaag
    55801 gatacctaaa cactggaaaa atattaaatt taatatatta tttagagata atttagtttc
    55861 tgtaaatata gaagaatata aatcttatta taagttaatc aaaggtaaaa acataagcat
    55921 attacatgat aataaagaaa taaaattatc aaagaacata atagaagtta ataattgttt
    55981 taaagggagt aattaatatg aaagcagtct tatttgatct tgatggagtt ataacagata
    56041 ctgctaagta tcattttgaa gcttggcatg agatagcaaa atcgctagat atagaaatag
    56101 atgaaacttt taatgaaaaa ttaaaaggca taagcaggga agaatcatta gataaaatat
    56161 tgttatctgc taataaagta gatagttata ctaaagagga aaagttaaag gtgtgtgaag
    56221 aaaaaaataa catttatata aagttaataa actcattaac atataaagat atattaccag
    56281 ggataaatga gcttataaaa gaacttaaaa aaaataatgt gaaattggga atagcatctg
    56341 ctagtaagaa tgcacctagg atattagaat ctttgggaat aaaagatgaa tttgattgta
    56401 tagtaaatcc atccttatta gaaaggggaa aaccatatcc tgatattttt attgaaggga
    56461 gcaagatgct aaatttaaaa caatatgatt gtgtaggaat agaagattct tattcaggta
    56521 ttaaagctat aaatgctgcc aatatgacat caattggtgt ggggaaaaaa gaagtactag
    56581 gaaaatgtga ccatattgta gaagatacta gcttattaaa ttacaataca ctattacaag
    56641 cttggagtaa aaagattaat ttggattaaa attatattaa aaattatttt aaaagagagg
    56701 ataaggtatg aagaataaat atgaagaagt agctcaattg ataattgatg gacttggagg
    56761 aaaggataat ataattgact taactcattg tatgacacga ttaaggttca tcttaaaaga
    56821 tgaaaagaaa gtcaatgcag ataaattaaa atctatagat aaggtagttg gagtaaactc
    56881 aacttcaact caatatcagg tcataatagg taatgaggta ggtgttgtat ttaatgcaat
    56941 aataaataag gggataaata ccacaggaga tattaaaagc gatataaaaa atgaaaataa
    57001 aaaaaatagt attttaaata atataataga tacaataact ggttgtatga cacctatgat
    57061 accagccctt acagcatctg ggatgataaa agttatatta tctctttgta ccacttttaa
    57121 ttggctatca tcaaattcaa gtacatatag agtattagat ataataggag atgtagcatt
    57181 ttactttatg cctataatac ttgcaataaa tgcagctaaa aaatttaatg ttaatacatc
    57241 aatagcagtt atagtagtag gtgtgttttt acatccaaat ttctctgcat gggtatcaag
    57301 tggggaccct atatcattta taggagtacc aattcaaggt gttatatatg cagcatctgt
    57361 tatccctgca cttttaacag tatggatgat gtcatatata gaaaaattca ttaataaatt
    57421 aacacctagc atgttaaaaa caattttaaa tccaacttta gtattattaa taagtgcgcc
    57481 aatagcatta atagtaattg gaccaatagg aaatttctta ggagagggat tagctagtat
    57541 aataaattta ctacaaggaa ggttaggatt tataatggtt tgtttattag cagctgcaat
    57601 gccatttatc gttatgacag ggatgcatca tgcattgact cctatattca tatcagcatt
    57661 tgcaactaca ggacaagaat cgctaatatt aatatctcaa gtttgtgcta atttagcgca
    57721 aggtggcgcg acattagctg tagcattaag aagcaaagat agtaagatga aacagttagc
    57781 atcagctgca tggatatcag ctatcatggg tataactgaa ccagctcttt atggagttac
    57841 attgaaactt aaaaaacctg ctatgttagc atctatagga gcaggaatcg cagggttatt
    57901 tgcaggaatt actcatgtga ctttatatgt tccacaaaat agtataatgg cagtacttgg
    57961 attatcaggg gaaaagggaa tttcaaatat agtaaatgga cttatagtta tatttatagc
    58021 attggttgct ccatttatta tgacatatgt ttttggagtt gaaaaaaatg ttaaggaaag
    58081 tacagataat gtagtagagg aagtataata ttaactattt acattaatag aatttttatt
    58141 attattgact ataacttgtt ttgtatttat attgatgcaa agaaataagt taatattaat
    58201 gataataatt attataactg acaaaaagca acacaaaaga ttgatgaagt atatggaaat
    58261 aaaaagttga caaaatatgt ctgatgtttt atcatattaa ttggaattag gtagtaattg
    58321 tttaagtaca agctaagctt attcattaat aatagcagta tcctaggaag gagtatgccc
    58381 attattatgg ataagctttt tttatgctta aaaggaggat aatcatgata attaataaga
    58441 tattaaacaa taatgttgta atcacattag atgataatga tgaagaagtt atcgttatgg
    58501 gtaaaggaat tggttatcaa aaatcaaaag gcaatctaat agataaaact aaagtaaata
    58561 aagtatttag aatatcaaat aaagaaatat caaacaaact acaagaatta ctcaataata
    58621 ttcctataga acacatgaaa ttatcaagtg aaattataga atacgcacaa ataaagttaa
    58681 acaagaagct aaatgaaagt atttacatat ccttaagtga ccatacatat tctgcaattc
    58741 aaagaatgaa agaaggaata aatgtaaaaa atgcaattct ttgggaaatt aaaagatttt
    58801 ataaagaaga gtttgaaatt ggaatgaaag cactagatat tattgaaaac aaaacaggta
    58861 taaaattacc agaagatgag gctggattta tagcctttca tatagtgaat gctcagttaa
    58921 gtgaaggtca tactttggca tctgatatta cgaagttaat acaagaagta cttagcatag
    58981 ttaggtatca ttttaggata gaatttcatg aagaatcagt gttttattat agatttataa
    59041 tgcatttaaa gttttttgcg caaagattgc ttttagatag tgcacatgaa ggtgagacag
    59101 acaaagaatt actaagcatt attaaatcta aatataataa agagtttgaa tgtgtagtta
    59161 aaattaaaaa tttcattaaa aaacaatata actacatatt aacagatgat gagcttatat
    59221 atttaacaat acatttagct aaagtagtta aagactcaaa tatgtaagtg aaataatttt
    59281 tcagtagtat attaagaatg attgaaagga gtgatactaa caaaattata cctatggttg
    59341 gatggtaaca ttgagttggc caaaccttca aatttcaaaa aattaattta aacgaaatat
    59401 ggaggagaaa aatgggaaaa tacaaacaat tagcacaaga gatagtaaac aatgttggtg
    59461 gaaaagaaaa tattagtgga ttagtacact gtattacaag attacgtttt actttaaaag
    59521 atgaaagtat agcaaatgac aatgtattaa aaaacatgga aggtattgtt actgtaatga
    59581 aaagtggagg acaatatcaa gtagttatag gaaatcatgt tgaagctgtc tataaagatg
    59641 tagttgaaat aattggttta gatgattcaa gtacaagttc agaaactaaa aaatcaggta
    59701 atatactaga taaaggtata gatataatat caggaatttt tcagccagtg ttaggaataa
    59761 tggcagcttg tggtatgctg aaaggattta atgcattatt tgtagcaatg ggattatata
    59821 gtgatgtatc tggtggttat atggtaataa atgcagcagg agatgcatta tttacattcc
    59881 ttcctttgtt cttaggatat acttcagcta agaagtttgg attaaaacca atgttgggat
    59941 tagcactagg agctgcagta tgttatcctg ctatacaagg tagcagtata tcagcaggag
    60001 cagatgtgat gtacacttta tttaaaggaa caatgtttgc atcaccagta tatattgatt
    60061 tctttggact accaattgta tcaattgatt atactggaac agtcgtacca attatattta
    60121 tagtgtattt tgcttctagg tgtgaaaaat tatttaataa gtttgttcca gatttagtta
    60181 agtttttctt tgtgccaatg cttacattat taataacagt gcctgttgca cttatagtta
    60241 taggtcctat cgcaacattt ggttctacac ttatttcaca aattgtaatt tcaataagag
    60301 attttagtcc actattggca ggtgctatag tagggtttac ttggcaaatt cttgttattt
    60361 ttggtatgca ctggggattt attcctgtat atataaacaa tgttatgact ttaggatatg
    60421 ataatgttat gatgccattc tttgcttgta catttgcaag ttcggcagtt gtgttggcaa
    60481 tatttttcaa gactaaagat aaaaaactaa aagagatgac aataccaaac tttatatctg
    60541 gtatatttgg agttacagag ccagcaattt atggagtatt attgccttta aagaaaccat
    60601 ttataataag ttgtattgct agtgggattg gaggcgcttt ctacggattc tttaatctta
    60661 gaaaatttat aactggaggt atgggaatat ttgaacttcc agcaatgatt gaaccagatg
    60721 ggggaatggg caacttaata gtagctcttt ctggtatagc tatatcaatg gtcgtagctt
    60781 ttgtattaac tatgatttta tataaagatg agaaagtaga agagtctaaa aaagtaagaa
    60841 ataaggggaa agaagaaata aaagaagtca agtctactaa attagaaaga gaaatagtag
    60901 caagtcctat aaaaggtgaa gtattaaaat taagtgatat agaggatgca gcatttgcat
    60961 ctggtgtact aggtcaaggg gtggcaataa tacctagtga tggaaaagta gttgctccag
    61021 tagatggtgt agttacaacc ttatttccta gtctacatgc tatagggatt ctttctgata
    61081 caggtgttga agtgcttatt catattggat taaatactat tcaattagaa gggagaggtt
    61141 ttgaggcatg tataaaacaa ggtgatagaa ttacaaaagg tcaaactata ttaaactttg
    61201 atgttgatgc aataaaagag ttggggtata gtactgtaac tccaattgtt attacaaatt
    61261 catcacaatt tttagatgta gtagaaacag aaagtaaaaa tattgaatta gaagataatc
    61321 taattacagt cttattttag taaaaattga ggcattagca taagctagtg ctttggttat
    61381 aatttaagga ggctttgact atgagtttta aggatgattt tttatgggga ggagctactg
    61441 cagccaatca atgtgaaggt ggatacaatg aagacgaaag aggattggca aatgtagatg
    61501 tatgtccaac aggaaaagat agaacagcag ttattacagg gaaactaaaa atgtttgatt
    61561 ttgatgatga gcattattat ccagctaaaa ctggtattga tatgtatcat aattataaag
    61621 aagatataaa gttatttgct gaaatgggat ttaaagtata tagaatgagc attgcatgga
    61681 gtcgaatatt tccaaaaggt gatgaagaaa caccaaatga aaagggactt caattttatg
    61741 aaaatatatt taaggagtgt aaaaaatata aaatagagcc tttagtcact attacacact
    61801 ttgattgtcc aatgcattta gttaaaaagt atggtgcatg gcgtaatcga aaaatgatag
    61861 gtttctatga gaaattatgc aatgttatct ttagaagata tagaggatta gtgaagtact
    61921 ggctaacctt taatgaaata aatatgattt tacatgctcc atttatgggt gctggtattt
    61981 gctttgaaga aggtgaagat gttgaaaaga taaaatatca agctgctcat catgagcttg
    62041 tagctagtgc aattgcaact aaaatagcac atgaagttga ttcaaataac ttagttggat
    62101 gtatgtttgc agctggaagt gtatatcctt atagttgtaa tcctaatgat gtatgggaag
    62161 ctacaaagtt agatagagaa aattacttct ttgtggatgt acaatctaaa ggtaaatatc
    62221 ctaactatgc gttaaagtat atggagcaaa aaggtattac accagaaatg gaacctggtg
    62281 atattgaatt attgaataaa tatacagtag attttatttc attttcatat tacaatagcc
    62341 gttgtgttag aactgatgaa aatgcagatg atatggctga aggaaacata tttacatctg
    62401 ctaaaaatcc atatctttca tacagtcaat ggggatggcc aattgaccca ttaggtttga
    62461 gaattacact aaatcatgta tatgatagat atgaaaagcc actatttatt gtagaaaatg
    62521 gattaggtgc taaagatata gctgatgaaa atggttatgt agaagatgat tacagaatta
    62581 attatctaag agaacatata aaagctatgc atgatgcagt ttctatagat ggggtcgatt
    62641 tattaggtta tactacatgg gcacctattg atttagtaag tgctggtaca ggtgaaatgg
    62701 aaaagcgtta tggatttata tatgtagata gagataatag tggtaatgga agtctaagaa
    62761 gaatgaaaaa gaaaagtttt gaatggtata agaaagtaat tgcttcaaat ggtgaagatt
    62821 tatattaaac aagaaatcta tgttaaataa gaaatttgta ttaaataaga agagtataaa
    62881 aattaataat aagtataatt tttaactttt ttaactatag aaaatcaata cagaattatt
    62941 ttacattgta tttatgcaat agtatgattc acaaataaaa ttttagaaaa taaaattgtt
    63001 aagaagtatg ggaagtaagt gcaatttact ttgtaataaa agatgaaaaa ggcgagctta
    63061 ggttttaagc ttgtcttttt tattatgtat aaactatgat actttaaaat tctatgaaaa
    63121 atttatttaa tagagaaatt aaaaatttaa tggtaatcaa attctttacc aatgaatata
    63181 aaaaatgtct acgtgttata atagtttaaa ctaataaacg aaaggtagat gaatgaatat
    63241 gaaataccaa catataatag aagttgacaa agaactttgc attggatgtg ggctttgtaa
    63301 aaatgattgt ccagtaaaca atataattat agaaaataaa aagtcagtaa ttaaaaaaca
    63361 agattgtcta atgtgtggac attgtgcagc aatatgtccc acaaaagcta ttaccttgac
    63421 aggatttgat gaacctccta tagaacttac aaataagcca aagctagatt cagatgaatt
    63481 actaatggca attaaatcta gaagaagtat acgtaaattt aaagacaaag aagtttcttc
    63541 agaaattgta aagcaaatta ttgaggcagg taggtatacc cctagtgcta aaaattcaca
    63601 agatgtatca tatattgttt tagacaataa aaagtcaatt tatgaaaacg aagcagtgaa
    63661 attttttaga aaaataaaac ctattgcaaa tatagctatt aaatattcaa aagaagttga
    63721 gattgacgat aactttttct ttaagcatgc tcctattgca ataatgataa ttacaaaaga
    63781 taagattagt ggttcacttg cagcatcaaa tatggcatta atggcagagt cttatggtct
    63841 aggtgtttta tttagtggat atttttcaga tgtagcaaat aattcgccaa aattaaaaaa
    63901 gcttttaggt ctaaaacgca gtaatcatgt tcttacaaca ttagtaattg gatacccaga
    63961 tgttaaatat agacgtactg cacagaaaga agtagcaact gttagatact tataagagag
    64021 ggtggatttt atggaaaaag aatgtcaaca aagaatgcaa gaaataacat ctaaatttaa
    64081 agaatgtcgc aaagctatct ctgctatggg tgatgagact agacaattga ttttaattgc
    64141 tctcttagag agtgatttta atggtatacg agtgggagaa atcacaaaaa aaacacatct
    64201 ttctcgtcct gctgtatctc atcatcttaa gatattaaaa gaagcagaga ttgttaattt
    64261 gcgtagagaa ggaacgaaaa attattatta tcttgattca aaaaaatcac aatggaagtc
    64321 actaacagag ctaataaatc ttatatttgt tggaatacaa catattagtg aaaatgatat
    64381 aagaaaaggt gattaaatta tacttgattt aatacaaaaa gattgattta ggaactaaaa
    64441 agttcacttt gagacactat cttttgaact atacccatct taggagacag ttaaaatatg
    64501 taaaactgta taaaacaatg ggtatagttc attttataat ggtttaaata ttaagaatat
    64561 attattctaa atagtatctt tctctgtttt gagttttatt tttatactca atagcttcag
    64621 tggggcaacc acaaatacat gccatacaat gagtacagct atttttccaa actggctttt
    64681 tgttttttaa attaatatta tttaaaggac atagctctac acattttcca cagccaatgc
    64741 atttatcagt ataatgaaat cctttggcac taataattgt cttataaaaa actgtattta
    64801 ttataccact tttaattgta cctcctaagc cactaggagt aatagtttca aattcatttt
    64861 cattgcgtat atcagaaata atcctatata tttgtttatc tgcttcttta atcatttgtt
    64921 ttgatgtttc tttgtctgtt gtagaaaata aagctatata attctctggc attttaattt
    64981 ctgccatacc ttttaattgc cattccttgt atttacatag tttttgaata tagtttatgg
    65041 attttgctgt atctccccca caagtcatta caaagtaaac tctgttgtct cctagaaatt
    65101 ttgtttcttt tataaaatct gtaaccacta ttggcaatct ccatgcataa gtaggacata
    65161 cgaatatgaa tggtttacct gctgatatta attcatctgt tttttcctct tttataagtt
    65221 gatttagtga tatcagttca tcatttaatt cttgtgcaat tttacgagcc acatatcggc
    65281 tattaccagt accgctaaaa tataaaatca taataatatc tccctaacta ttttttattt
    65341 taactcttaa ttttttattt attatagtac tttattgaaa tattctattc aaatgtatgt
    65401 aaaatttagt agttaagaaa attataacac attagtaatt tttatattca ttggtaaaga
    65461 atttgattac cattaaattt agtaacaaaa tatcaactgg atttttatat aagaagagat
    65521 agtaattttc atgtgaaaga ttgtaaatat aaagatgatt ttgaagggca ataagaagat
    65581 aaaattgata gcttaataaa aaatatttaa cttttatatt aactgtttta aatattataa
    65641 ttatctatct tgaataatca accatagaag actgtataca aagacaaagt tgtgtacagt
    65701 cttttttata aatttaatgt ctataattaa atacactatt aaaatcaata agttattatt
    65761 tcaaagtagt attatccaaa tttttatgat ggttaataca atttgttagc cattttatag
    65821 caccttgttc cctgataata gctccatcaa gaactatata atcaccaaaa tcattactat
    65881 caagaggagg aacttcacta taacgctcca tttgactgta caagaacgta attctttctt
    65941 ggtgttgaag caattgatgc tctagtaaaa taagcctagt atctatatct aaattattag
    66001 aaaaatacat tctaagacga aaaatatcct taggggttct ttccattggc tcatcctttt
    66061 caagccattt caagaactca tctttacctt tttctgtgat tgtgtataac tttttctcta
    66121 atacatcacc actaatttta atatcatata caataagctt ttcatttacc aattttttta
    66181 gttcaggata tatttgacta tgctttgcat tccaaaactc agctaattga aaattgaact
    66241 cctttacgat atcataacca gtcataggat ttctatttaa taatcctaaa attgcatact
    66301 ttaaagttcg cataaataca cctctttctt taattacata cttattataa cacgatatat
    66361 ttagtttgaa ttaattaata tagctatgtt ttaataagaa cttttaaatt atgaggaaca
    66421 aaaaataaat aaaactatat ataaaaatga aattatgtaa atataaacat gtaagtattt
    66481 acatgtttat atttacatat agaaaaaatt gtgataatct taactaagaa attctattta
    66541 ataaatttat cgaggaggag agtaatgaat ttaacacaaa aaagatggat tatattaatt
    66601 gcaagttgtt tcatcaattt atgtattggt tcaatatatg cgtggagtgt atttgcatca
    66661 cctatggcag aacatttaaa tagtcttgct ggaacaactt ttacagctgc tagtttagca
    66721 attgtattta cagttacaaa ctcagttgga cctattacta tgattacagg gggaatgata
    66781 aatgataaat ttggtcctaa aaaagttgta tttgtaggag gattaatttt tggtataggt
    66841 atgatattgg caggtttctc aaaaggattg cctatgttga ttttatcata tgggataata
    66901 acaggtcttg gggttggcat ggtttatgga tgtacaataa gtaattcaat taaatttttt
    66961 ccagataaaa gtggattagt tggtggtata acaacagcag cttatgggtt tagttcagta
    67021 ataatgcctc cagttgctaa ttggataatt aataaatatg gagtaacttc tgcatttaaa
    67081 tcaataggtt tagtatttct tataattgta tgtgtttctt ctttctttat caaaaaatgt
    67141 ccagcagatt tcacaccaga aggatgggta ccaccagaga aaaaaggaaa agtaagagtt
    67201 gttattaata aaaattggaa agaaatgctt tcaacaccta tattttatct aatgattata
    67261 atattaactt gtggagcttt ctatggatta atgtgtgtgt cattagcatc ttctctagca
    67321 acaaatatga ttgggatgac aagttcagat tcagcaatag tggtttcaat tttagccttg
    67381 tttaatacat taggccgtat tgttgcagga tatatatcag ataaaattgg tagaataaat
    67441 actttatcag gtgcattagt tatttcaatt tttggtttat tatgtttgtt attctcaaga
    67501 gaaggagatg tagcaacatt ctatattgga ataataatta taggtatatg ttttggttca
    67561 tttatgggaa ttttcccagg atttacagta gataaatttg gacctaaaaa taatagtgta
    67621 aattatggaa tcatgtttat tggttttgct tttgcaggat atattggacc tgcagtgatg
    67681 aaaaatgtat attctgtaga tggcaattat caaagggctt tcattatagc tataattata
    67741 gctttaatag gttttatatt aacattttta tataaatata taaataaaat acaaaattta
    67801 aagatagaaa atttaataaa gggagatata aaaaatggaa agaaaatatc caaatctatg
    67861 taagccaatt aaaattggaa atgtaacatt caaaaacaga atgttttcag cacctatggg
    67921 gggaacagac ataacagcag attgtacaat tggctcaaaa tcaacagcct tttacgaatt
    67981 aagagcaaaa ggtggagcag gtgcagttac aattagtgaa tgtatggttc atccagaaac
    68041 agatggttca catgcatatc atctagactt aaaaatagtt gattccttag caagttttac
    68101 ttatacagca gatgcaattc gccgtcatgg agcaatacca agtgtagaac tatctcattc
    68161 aggacaatat tcaggaactt atttagttga caaagataag aagcgaggat tatcacaatg
    68221 gggagtaagt cctagtgttc gtcctgatgg attagagata aaagaactta cagaagaaat
    68281 aattgctgaa atagtagagt catatggaaa tgttgcagca ttggctaaga gagcagggtt
    68341 tgagatgatt atgattcatg gtggacatgg ctggctaatc aatcaattct tatcacctta
    68401 ctttaataaa agaactgaca aatatggtgg ttctttagaa aacagagttc gttttgctaa
    68461 agaagtttta gatagtgttc gtaaagcagt aggtccagga tttccaatag agtttaggat
    68521 gagtggttct gaattatttg agggagggta tgatttagat tatggaacag aaattgctaa
    68581 attattggaa tcaagagtag atttacttca tgtatcagca ggtacatacc aaagagggtt
    68641 tgcagtaaca catccttcta tgttcttaga acatggatgt aacgtatatc ttgcagaaga
    68701 aattaaaaaa catgtaaata ttccagttgc tactatagga gcattaaatg acccagaaat
    68761 gatggaagag ataattgcta gtggaaaagc agatgttatt tacatggctc gtgcattact
    68821 agctgaccac gaattaccaa gaaaagttat gagtaatcaa gatgaaaaaa tagtgaaatg
    68881 cctaagatgc ttcacttgta tggcagaacg tgctaccact tctacaagac gctgcactgt
    68941 taatccactt attggacgtg aattagatgg aactgaagtt gtttcagtat taaaacctaa
    69001 aaaagtatta atagcaggtg gtggaccagg aggattgcaa gcagccatta cagctgtaaa
    69061 gcgtggacat aaagtaatac tttgtgaaaa aactaatgaa ttaggtggaa ttttaaaggg
    69121 agaacaagca cttccattta agtataaaat gtatgaatta ggaaatactt ttggaaaaat
    69181 agcaaaagat ttaggtgttg aagtacgttt aaatacaaca gttacaaaag aatatgttga
    69241 aaatgaaaat gtcgatgcat taattatagc agtagggtct gaacctcttg ttccaccaat
    69301 agagggtctt gatggagaaa atgtagtaat agttaatgat tattacgtag aaaaagaaaa
    69361 agtcactgac gaagtaatag ttttaggtgg aggattagca ggatgtgagg ctgcaattca
    69421 cttagctcaa gaagagaaga ctgttcactt agtagagatg agagcagaac ttgccccaga
    69481 tgcaaatata aggcatcgtc caatattatt agaagaaata gaaagacaag gtatatatgt
    69541 atatacagaa cataagggtt taagtgtaac aacagaaggt gtagtatgta tgaataaatc
    69601 tgggaataaa ataaatattc caggaacctc agtaatatgt gcacttggac aaaaaccaag
    69661 aagagaagtg gtagacactt tacttgattc tgctccatat gttgctcaaa ttggagactg
    69721 tgttcgtgca tctacaataa caaatgcagt ataccaaggg catcatgctg cgctagatat
    69781 atagttaaaa agacgtagat agtattgttt tattataaaa aaggagtgtc tcaaaatgaa
    69841 ctttttagtt catgagacac ttttttacat gaaattaaat atatttttat catttcaaca
    69901 atgaaaaaag attatcttta ttttgagaca gcacttttgt tattatgatt ttaattctta
    69961 ttgcaagttt tcatttgatt gatgagtaaa actttttaag atgtagaagt atttaacaat
    70021 gtaaatgacc ctaacttaaa tactttagcg aaggttgaca gatttgtgtt tgcttttatc
    70081 tattataact taaggaaaca tgttacctga acaataaatt tatataataa aagtatataa
    70141 atatatatat gaatgttaag attagttgat agaatttaaa taataaatcc aatattataa
    70201 acataggagg tatgaaaaat atgattaatg agaatttaaa aagtctaaga aaaatccacc
    70261 agtatacaca agaagaatta gctgaaaaac ttaatgtttc tagacaatca atagcaaaat
    70321 gggaaagtgg agtttcccaa acaaaaggat attactgaaa taacctgtgt ttacctgctt
    70381 gtagagaaaa gaatattgct attaagccag agatactaca taaatgtgtt ggtatctctt
    70441 tttcgttaat gcaacacagt aaattatttc attttcctaa ttattttaga ctgataagta
    70501 actttttaaa tgaagaaaag aaatgacaat acttaaagga gcatggtata cttaaaggag
    70561 aatttcatta aggaggaaaa agagattgtt taatctaata gaaatgttat ttcctataat
    70621 gtttatactg atttttataa taattgtttt cacttttgtg aaaggaatag ctacttggtt
    70681 taaaaacaat aattctcctc gcttaactgt gtcagcaaga atagtagcaa aacgtcagaa
    70741 taccactcat aacaatcaac caaacgctgg tgatatatca ggagcacatg gatttcatac
    70801 aatttccagc acctcgtatt atgtgacatt tcaagtagat agtggtgata gaatagagct
    70861 gtctgtatct ggctcagagt atggagtgct tgcagaggga gataaaggac agctgacatt
    70921 ccaaggcaca agatatttaa catttgatag ggaaaattga atttagaggt gcattatgaa
    70981 taagtttttg agtcagataa ggcgtataga taatgaaata tctattacta ggaaaattat
    71041 aaatacaata tttatactgt gttttggaat agttttagga acttttgcaa aatttttaga
    71101 tactacagca agcaatactt taccatttat atttgaatat ttagatatta gtaatttttt
    71161 tggtcgtttt gctatatggt tattgattgc tttgtacatt gcaatttata gtcattcttc
    71221 cataagagca tcattaaatg tgttagtatt tttcattgga atggtttcaa gttattacct
    71281 atattcgtat tttgttgctg gattttttcc aaaaaattat gcaatgattt ggcttggttt
    71341 tactgtcatt tctccattgt tagcttttat ttgttggtat gctaagggga aaagcaaaat
    71401 atcttttata ctttcagtaa taataattgc aattttattt aattttacat ttatttatgg
    71461 ttggatttat tttgatgtgt attcaatttt agaagtgata gtctttggtt gtgcattaat
    71521 agctttaaaa cgtaacacct ttagggagac aacgtatatg atattgagtg cagttgttat
    71581 tgctgttata cttaatatgt tagttccatt tcattttggt taggcagatt ttaagattat
    71641 tatagataga atataaattt cacgaaccgc cgaagcgatc cgccagcggt ggcggtcgta
    71701 agacatatcg ccacgccagc ttgctggcga ggtggcggtt cactttggcg gtttggcgag
    71761 cctgcgagct ttctaagccc ccgttatcta acaggggggg actattacaa aagacaagag
    71821 caaaaacaaa tataaaactg ctgatatgca acgatttata aggttgtaag aacttatttc
    71881 actttacacc ctattctttc tacccgacag gtctaaaaca gcatatcaat agaaaataaa
    71941 tataagatac aaggtgtatg ctcctatgag tatatgcctt tttttgattg gaggaatgaa
    72001 gcatgaatga tatgaaattt attgaaacat taaagcaaaa gagaaatgtc tgtgattatt
    72061 cgcaatcacg actggcacag gaactacaaa tcaacaggca gaacttaaat gaaattgaaa
    72121 acggaaaaac aaaagccagt aaagaaatga aacatatact cttacattat cttgattatt
    72181 gtaattgtac acagcctttc actttaacga ttgactatct gcgtgttcgt tttcctacca
    72241 cagacgcatt ggaaattata aaaaatgtgc tggcaatgaa aagcgaatat tttatacatg
    72301 aagattacgg aatgtatgct tatgaagaac agtatatcta tggggatatt agtgtaaatg
    72361 cttctaaaga tagttctatg ggtgttttat tggaattaag aggtatgggg tgtcgggact
    72421 tagaatatgt tttacaggta agagggatag actggtattg ctttttaaga tgttgtatag
    72481 attatcaagg tgtttttaaa cgcatagatt tagcagtcaa tgatatgggc ggattgctgg
    72541 atatagaaat tctaagggaa cgttattatg ctaacaaggt atggaaacgt tcaagaaccc
    72601 atgaagcagt agacagcgga aaattatcgg gtacacatgg agatactgca aaaacttttt
    72661 atatcggttc aaagaatagt tctatctact tttgcttgta tgaaaaagaa aaggaacaaa
    72721 aaagcaaggg tataaaaaca gatattaaga accgcttcga aattcgttta aaaaatggaa
    72781 aagcaggaca aacggtagag caacttgttt tttcaagaaa tcccgaacag accatagcaa
    72841 gctttattct cacacagata gattttcccg attatatttt atgggatata tttttagata
    72901 atgtaacgac ctcacttccg tttattatga cacctgttgc tgttaatatg gataaaataa
    72961 aacgctggct agaaagacag gtcatgccct ctttattgat gataaaagag attgaaaaga
    73021 aaacaggagc aaattatctg gaagaaatcg acaggcatac aaggctaaca gaaaagcagt
    73081 aattaaagat taaacaaatg acaacagaca tagcagatat gattgagaaa gataccgctg
    73141 ttccacaagg gaatgacggt attttttaat ttcttcaaaa aaactgcaac aaaatgactg
    73201 cttgtgtaca gatatggtgc gaggaaagga aatctaactt tttttgaaaa caggtcatta
    73261 aatcggtggc tgctgtccct atatgatgtg aaagaagaaa cgatttttaa tttcaactta
    73321 acatttgaca gttttcattc cctatatgga gcaaagaaaa tcttttattc catagttggc
    73381 agttacggtg ttgcatgggt agttagggtg tgaaaagaaa aacagatttt tttcatcacc
    73441 aacttagcaa actgatactt gctttcccta tatggtgcag gaaaagagag tttaactatt
    73501 ttcatttcaa cttagcaact ggacgtttgc tgtacagata tgtagtgaaa agagaaaaag
    73561 ttttgaatat tggttacgct tcggctcttt tccaacgcgg tatataggaa agacgatttt
    73621 cttctttcat gttctttgac aactgaataa agcaattcaa tacgtttgac agacagcgat
    73681 ccattgaagc agatacgcca tgaccttttc cctgcaaaag cgagcgaacc ctatttgtgt
    73741 tcctgtaaaa gacttgtcct cttttatcgc catgacctgt tctgtctgat aaatgatact
    73801 cccgtacagc cacagcttga acgttcagag cgtcgcacgc aatgggtacg gctacataag
    73861 aactatgcag aggtggaatt cctgtgggct atgacaaatg ccgttgaatt gcttagaaaa
    73921 aagattatgg aaagggggta tgtgttattg ctgatattgt aaaaacaatg caagaaaaga
    73981 caaataataa gcgtagcatt ggcaacagag gaaaaacaaa gattgttgta aaagagcatt
    74041 tttccgaaaa gggaaagaca atggaggaac ttctgactga tgttatgctg gaaaaagcaa
    74101 agcagacaat cgcataaaat tggtgcagtt gtaagacata gattgaatgg caaaaagtac
    74161 ccgtgttata ctttacttgc aagcaggtat tgtaaacacg ggttagttat aaaggaggat
    74221 aactgacaat gaaacaacag atttacaata ctgcacttta tcttaggtta agccgagatg
    74281 atgaattaca gggcgaaagt tccagcatta ccacacaaag aagtatgttg cgtctatatg
    74341 caaaagaaca tcatttgaat gtgattgatg aatatattga tgacggctgg tcgggaacaa
    74401 attttgaaag accgagtttt caaagaatga ttgaggatat agaggcagga aaaatcaact
    74461 gtgttgtaac gaaagacctt tcccgacttg gcaggaacta tattatgaca ggacaatata
    74521 cagaattgta ttttcccagc cataatgtcc gttacatagc gattgacgac ggtgtagaca
    74581 gcgagaaagg cgaaagtgag attgcaccat ttaagaacat catcaatgaa tgggtggcaa
    74641 gagatacaag ccgtaaagtg aaatcggcat ttaagacgaa atttgcagag ggtgctcatt
    74701 atggtgctta tgctccatta ggatataaga aacaccctga catcaaagga aaactgctgg
    74761 ttgatgatga aacaaaatgg attgttgaaa aaatcttttc cctagcctat caaggttatg
    74821 gtagtgccaa aatcacaaag gtactgcgag aggaaaaagt tccgacagcg tcttggctga
    74881 attttacaag gtacggtact tttgcacata tctttgaggg aaagcccgaa agcaaacgtt
    74941 atgagtggac gattgctcat gtcaaggcaa tcttaaaaag tgaggtttat ataggcaaca
    75001 gcgttcacaa tatgcagtct acggtttcat tcaagagcaa gaagaaagtg cgtaagcccg
    75061 aaagtgaatg gtttcgagtg gaaaataccc atgaaccgat tattgacaaa gaagtgttct
    75121 atcgtgtgca ggaacagata aaatcaagac gtagacagac aaaggaaaaa gcaacaccga
    75181 tatttgcagg gcttgtcaag tgtgcggatt gtggctggtc tatgcggttt gcaacgaata
    75241 cggcaaataa aacgccttac agttattatg cttgcagtta ctacgggcag tttggcaaag
    75301 gtacttgttc tatgcactat atccgttatg atgtgttgta tcaagccgta ttgaaacgat
    75361 tgcagtattg ggctaaggca gtacagcagg acgaagaaaa ggtgctgaac aagatacaga
    75421 aagcaggcaa tgcagagcga atacgggaaa agaagaaaaa ggcaagtgcc tttaagaaag
    75481 ccgagaaccg acaaaatgaa attgaccgtt tgtttgcgaa aatgtatgaa gatagagcct
    75541 gtgagaagat aacagagcga aattttgtga tgttgtctag caagtaccaa aaagaacaaa
    75601 tagaactgga acagcagata accaacctaa gagaagaatt aagtaaaatg gaacaggata
    75661 tgataggtgc tgaaaagtgg attgagttaa tcaaggagta ttccgtacca aaggaactga
    75721 cagcaccgtt attaaatgca atgatagaaa aaatccttat tcatgaagca ataacgaatg
    75781 aggataacga aagaatacag gaaatagaga tatattaccg atttattgga aaagtagact
    75841 gataaagagg gttcatatct ttaactaagg gaaactggag aatctattcc tgatataggt
    75901 agttgcatta aacttgcaaa attgtacaag gtcaaactag atgacttagt taatcattcg
    75961 gaagaaaaaa caggtattat agtacctcct aaaggaaagt ttttctttgg agcagtagta
    76021 gttggtgaac gtggtcagat tgtcattcca aaagaagcaa gagaagtatt taatataaat
    76081 gcaggagata aattattggt acttggagat gaggaaagag gattaggaat tgttcatcaa
    76141 cgtgatttga taaattttat aggtcatatg ggagtagtac gtaaagaaga atgattttaa
    76201 aaaattataa aaggaggtat gaaatgtgag taaaatagta ttttttagca ttcttgcata
    76261 tggtcatact aatcctacta ttgaagtagt tcgtgaatta gtggatagag gaaatgaggt
    76321 attgtattat tcttttaatg aatttaaaga taaaattgaa ggtgctggag caaaatttat
    76381 ttgttgtgat aaataccttc cagaattact ccctggagat gagaaaaaaa ttggtaagga
    76441 ttttcctgga ttaattgaga tgatagtaga tactactatt tctttagatg aaaaagtttg
    76501 tagggaactt aaagatttta atccagattg cattgtatca gattcattaa gtttttgggg
    76561 aaagttattt gcacaaaaac ttaatattcc atatgtatgc tctacaacaa cttttgcatt
    76621 taataaacat acagcaaagt tgatgaaaca aaactttata gaaattatac gtatgatttt
    76681 tggtgtaaga cgcattaata aaaaaataaa gcttttacaa agaaaagggt atgaagtaaa
    76741 aaattttatt tctatagttt ctaatgataa tgatacggat accattgtat atacatcaaa
    76801 agaatttcaa ccaatggtag aaaccttctc tagtaagtat tcatttgtag gtccatcagt
    76861 atcaaagttg attattaaac ctaaagagag aaaaagaaag ttaatatata tttcgcttgg
    76921 tacaattaat aataaaaatg ttagctttta taaaaactgt ataaatgcat ttaaagattc
    76981 tgatgttgat gtgattatgt ctgttggtag aagtactgat attaaaagtt taggaaatat
    77041 accaaataat tttgaggtta aaaatagtgt tgaacagatt gctatacttc aaaaaactga
    77101 tgtgtttatt actcattctg ggatgaatag tgttaatgaa agtttatatt atggagtacc
    77161 catggtatta tttcctcaac attcggagca gagaatggta gctaagagag ttgttcattt
    77221 gggagcagga attatgttaa aagaggataa gtccgaaagt attaaaaaag cagtatttca
    77281 agttataaat gacaatgaat ataaagaaaa tgcaactaaa ctatcaaaaa gcttttataa
    77341 tgcaggaggc tcaaaaaaag cagcagatgt aatattacag attatatgta atagtagaca
    77401 agttgacata taatagattt gttaaaaata tatatacata catgcaattt aatcaaagta
    77461 ctgacagtgg ggtcttttaa cctaccagtt ggggcatata tattgatgct aaatatgagg
    77521 gatgttatat tttaataaaa aagataacat ccttttttta gtgcgttata tcaagtttta
    77581 aataataaat gaaggaggat taatatgaaa aaatataaag ttatttttat agtattaatt
    77641 ataggtatta taagtgtaac agggtttgtt gtatataaaa actgcattaa accatggaaa
    77701 gatgctgaaa catatattga taagtatatg gtaaaacaag atatttcaaa agataatata
    77761 aaaagtatta caaaagaaaa agccaagaag gcaagttacg aaggaatact atacaaagtg
    77821 tattacaaag atgaccctcg atatgagtat caatattttt atagtgataa ttatcatgct
    77881 ctatatgtaa ataaagtaat gttacaaatt tatgatgtgg aaaataataa taaactttta
    77941 agaagtaatg aggaattaaa aagtgtaaag tatccaccaa tatatcttaa atataagcca
    78001 gataaatgat ttatgacaaa atagaatgat ttttattaaa atttatttaa aaatatcact
    78061 a
//
LOCUS       DAEQJM010000014        74182 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.014, whole genome shotgun sequence.
ACCESSION   DAEQJM010000014 DAEQJM010000000
VERSION     DAEQJM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 74182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74182
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.014"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            249..770
                     /locus_tag="KRQ43_001197"
     CDS             249..770
                     /locus_tag="KRQ43_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2741561.1"
                     /translation="MDIAKLILNPARLRILQYIRLHGSARTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVVDNDKTK"
     gene            804..1580
                     /locus_tag="KRQ43_001198"
     CDS             804..1580
                     /locus_tag="KRQ43_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2741562.1"
                     /translation="MKFHEFGDKNKPHIMLIHGGGNAWWNYLRQAEVLSNNYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKM
                     FQSYVPSCEIYEAKGYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            1923..2876
                     /locus_tag="KRQ43_001199"
     CDS             1923..2876
                     /locus_tag="KRQ43_001199"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HBH2741563.1"
                     /translation="MINVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            2894..3913
                     /locus_tag="KRQ43_001200"
     CDS             2894..3913
                     /locus_tag="KRQ43_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HBH2741564.1"
                     /translation="MFKKCIKVVTLTFILACILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEENTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            3944..4195
                     /locus_tag="KRQ43_001201"
     CDS             3944..4195
                     /locus_tag="KRQ43_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741565.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIIGTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            4477..6282
                     /gene="lepA"
                     /locus_tag="KRQ43_001202"
     CDS             4477..6282
                     /gene="lepA"
                     /locus_tag="KRQ43_001202"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBH2741566.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDERRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            6433..7770
                     /locus_tag="KRQ43_001203"
     CDS             6433..7770
                     /locus_tag="KRQ43_001203"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBH2741567.1"
                     /translation="MINIEIPKKVDYIIKELETNGYEAYVVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLISTEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILRRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGHILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            8003..9316
                     /locus_tag="KRQ43_001204"
     CDS             8003..9316
                     /locus_tag="KRQ43_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH2741568.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTIISLGGIFITLLGLPVYYYMKKR"
     gene            9488..10663
                     /locus_tag="KRQ43_001205"
     CDS             9488..10663
                     /locus_tag="KRQ43_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBH2741569.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMKLY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINVDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            10766..11785
                     /gene="hrcA"
                     /locus_tag="KRQ43_001206"
     CDS             10766..11785
                     /gene="hrcA"
                     /locus_tag="KRQ43_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HBH2741570.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            11815..12435
                     /gene="grpE"
                     /locus_tag="KRQ43_001207"
     CDS             11815..12435
                     /gene="grpE"
                     /locus_tag="KRQ43_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBH2741571.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            12527..14374
                     /gene="dnaK"
                     /locus_tag="KRQ43_001208"
     CDS             12527..14374
                     /gene="dnaK"
                     /locus_tag="KRQ43_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBH2741572.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLADEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            14585..15739
                     /gene="dnaJ"
                     /locus_tag="KRQ43_001209"
     CDS             14585..15739
                     /gene="dnaJ"
                     /locus_tag="KRQ43_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBH2741573.1"
                     /translation="MSTKRDYYEVLGISKDAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            16705..17640
                     /locus_tag="KRQ43_001210"
     CDS             16705..17640
                     /locus_tag="KRQ43_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH2741574.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     AEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKDYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            17676..19049
                     /locus_tag="KRQ43_001211"
     CDS             17676..19049
                     /locus_tag="KRQ43_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2741575.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEGNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(19237..20004)
                     /locus_tag="KRQ43_001212"
     CDS             complement(19237..20004)
                     /locus_tag="KRQ43_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2741576.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFYFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(20034..21143)
                     /gene="ugpC"
                     /locus_tag="KRQ43_001213"
     CDS             complement(20034..21143)
                     /gene="ugpC"
                     /locus_tag="KRQ43_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBH2741577.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDKIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            21402..22139
                     /gene="cas6"
                     /locus_tag="KRQ43_001214"
     CDS             21402..22139
                     /gene="cas6"
                     /locus_tag="KRQ43_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH2741578.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGN
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            22144..23619
                     /locus_tag="KRQ43_001215"
     CDS             22144..23619
                     /locus_tag="KRQ43_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741579.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     GNTRNLGKKMIDNGNLSNLKELLLDNISVLRQLTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            23639..24652
                     /locus_tag="KRQ43_001216"
     CDS             23639..24652
                     /locus_tag="KRQ43_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBH2741580.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIIFGKKGNIYPSIKQNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEKEENEVLR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDKLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            24668..25474
                     /gene="cas5"
                     /locus_tag="KRQ43_001217"
     CDS             24668..25474
                     /gene="cas5"
                     /locus_tag="KRQ43_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBH2741581.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIKKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVMPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCNVCIDTKEVFTWL"
     gene            25501..27909
                     /locus_tag="KRQ43_001218"
     CDS             25501..27909
                     /locus_tag="KRQ43_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH2741582.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLLEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQEEIYDYIE
                     KGILEKEEFNLKDIESYINDILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDDMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEGALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     NYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            28350..29297
                     /gene="prmA"
                     /locus_tag="KRQ43_001219"
     CDS             28350..29297
                     /gene="prmA"
                     /locus_tag="KRQ43_001219"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBH2741583.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQDGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            29316..30074
                     /locus_tag="KRQ43_001220"
     CDS             29316..30074
                     /locus_tag="KRQ43_001220"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBH2741584.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            30076..31374
                     /gene="mtaB"
                     /locus_tag="KRQ43_001221"
     CDS             30076..31374
                     /gene="mtaB"
                     /locus_tag="KRQ43_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HBH2741585.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            31417..31767
                     /locus_tag="KRQ43_001222"
     CDS             31417..31767
                     /locus_tag="KRQ43_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HBH2741586.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            31930..32109
                     /locus_tag="KRQ43_001223"
     CDS             31930..32109
                     /locus_tag="KRQ43_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBH2741587.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            32139..32582
                     /locus_tag="KRQ43_001224"
     CDS             32139..32582
                     /locus_tag="KRQ43_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBH2741588.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            32693..33190
                     /locus_tag="KRQ43_001225"
     CDS             32693..33190
                     /locus_tag="KRQ43_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBH2741589.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            33383..33946
                     /gene="raiA"
                     /locus_tag="KRQ43_001226"
     CDS             33383..33946
                     /gene="raiA"
                     /locus_tag="KRQ43_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH2741590.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            34159..34395
                     /locus_tag="KRQ43_001227"
     CDS             34159..34395
                     /locus_tag="KRQ43_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HBH2741591.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            34408..35751
                     /gene="yqfD"
                     /locus_tag="KRQ43_001228"
     CDS             34408..35751
                     /gene="yqfD"
                     /locus_tag="KRQ43_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HBH2741592.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            35690..36805
                     /locus_tag="KRQ43_001229"
     CDS             35690..36805
                     /locus_tag="KRQ43_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBH2741593.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKVKMQEKTFKRK"
     gene            36862..37323
                     /gene="ybeY"
                     /locus_tag="KRQ43_001230"
     CDS             36862..37323
                     /gene="ybeY"
                     /locus_tag="KRQ43_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBH2741594.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            37329..38048
                     /locus_tag="KRQ43_001231"
     CDS             37329..38048
                     /locus_tag="KRQ43_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBH2741595.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            38167..38568
                     /locus_tag="KRQ43_001232"
     CDS             38167..38568
                     /locus_tag="KRQ43_001232"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBH2741596.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            38632..39525
                     /gene="era"
                     /locus_tag="KRQ43_001233"
     CDS             38632..39525
                     /gene="era"
                     /locus_tag="KRQ43_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBH2741597.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            39537..40916
                     /gene="mgtE"
                     /locus_tag="KRQ43_001234"
     CDS             39537..40916
                     /gene="mgtE"
                     /locus_tag="KRQ43_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBH2741598.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            40989..41144
                     /locus_tag="KRQ43_001235"
     CDS             40989..41144
                     /locus_tag="KRQ43_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HBH2741599.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            41110..41883
                     /gene="recO"
                     /locus_tag="KRQ43_001236"
     CDS             41110..41883
                     /gene="recO"
                     /locus_tag="KRQ43_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBH2741600.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            41876..42475
                     /locus_tag="KRQ43_001237"
     CDS             41876..42475
                     /locus_tag="KRQ43_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HBH2741601.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            42635..43513
                     /gene="glyQ"
                     /locus_tag="KRQ43_001238"
     CDS             42635..43513
                     /gene="glyQ"
                     /locus_tag="KRQ43_001238"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBH2741602.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            43513..45579
                     /locus_tag="KRQ43_001239"
     CDS             43513..45579
                     /locus_tag="KRQ43_001239"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBH2741603.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIRLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(45745..47292)
                     /locus_tag="KRQ43_001240"
     CDS             complement(45745..47292)
                     /locus_tag="KRQ43_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HBH2741604.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            47572..48339
                     /locus_tag="KRQ43_001241"
     CDS             47572..48339
                     /locus_tag="KRQ43_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH2741605.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            48622..48819
                     /locus_tag="KRQ43_001242"
     CDS             48622..48819
                     /locus_tag="KRQ43_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2741606.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            48848..49924
                     /gene="vorB"
                     /locus_tag="KRQ43_001243"
     CDS             48848..49924
                     /gene="vorB"
                     /locus_tag="KRQ43_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH2741607.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            49927..50646
                     /locus_tag="KRQ43_001244"
     CDS             49927..50646
                     /locus_tag="KRQ43_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH2741608.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            50659..51198
                     /locus_tag="KRQ43_001245"
     CDS             50659..51198
                     /locus_tag="KRQ43_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH2741609.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            51355..52413
                     /gene="buk"
                     /locus_tag="KRQ43_001246"
     CDS             51355..52413
                     /gene="buk"
                     /locus_tag="KRQ43_001246"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH2741610.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            52431..53324
                     /locus_tag="KRQ43_001247"
     CDS             52431..53324
                     /locus_tag="KRQ43_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH2741611.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            53354..54562
                     /locus_tag="KRQ43_001248"
     CDS             53354..54562
                     /locus_tag="KRQ43_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH2741612.1"
                     /translation="MKYAKRMDMVKASAIRASQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDIVVTENPSYLGAINAFRPYECDFLGVDTDDEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            54586..55848
                     /locus_tag="KRQ43_001249"
     CDS             54586..55848
                     /locus_tag="KRQ43_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2741613.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFSTPVLGMRWVMISLGILSIVMCPVLWFVIKDVDIREDKEEEASEKMSAGDFM
                     TVLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFG
                     APFGGYCADKVKSPTKVLLPIYVFGIAVIILFLVLPASTPMTIFIALTFVVGILGYMG
                     KGIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIF
                     QIAILIIGILSCLYILKVKKKRESKLEA"
     gene            56424..57887
                     /locus_tag="KRQ43_001250"
     CDS             56424..57887
                     /locus_tag="KRQ43_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH2741614.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSMKLRFFQIKDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSILFSVVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVTSSIALGIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIIANINLVPGAIMTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIIITGMYNVTDVYTTLPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKHIIN
                     VCRFMLIICAAMCCFIEPLTSWALGDICIGVLTYINLVGIFTLKKPAIKAYYDYQRQK
                     KMGVKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            57943..59079
                     /locus_tag="KRQ43_001251"
     CDS             57943..59079
                     /locus_tag="KRQ43_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH2741615.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            59315..60430
                     /locus_tag="KRQ43_001252"
     CDS             59315..60430
                     /locus_tag="KRQ43_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBH2741616.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALTPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKAKKIGEKELMNLLSLKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            60582..61451
                     /locus_tag="KRQ43_001253"
     CDS             60582..61451
                     /locus_tag="KRQ43_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH2741617.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
     gene            61827..62372
                     /locus_tag="KRQ43_001254"
     CDS             61827..62372
                     /locus_tag="KRQ43_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBH2741618.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
     gene            62385..63398
                     /locus_tag="KRQ43_001255"
     CDS             62385..63398
                     /locus_tag="KRQ43_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBH2741619.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            63620..65593
                     /locus_tag="KRQ43_001256"
     CDS             63620..65593
                     /locus_tag="KRQ43_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH2741620.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKENNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            65662..66021
                     /locus_tag="KRQ43_001257"
     CDS             65662..66021
                     /locus_tag="KRQ43_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741621.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            66056..66412
                     /locus_tag="KRQ43_001258"
     CDS             66056..66412
                     /locus_tag="KRQ43_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBH2741622.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            66449..67741
                     /locus_tag="KRQ43_001259"
     CDS             66449..67741
                     /locus_tag="KRQ43_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH2741623.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            68177..68815
                     /locus_tag="KRQ43_001260"
     CDS             68177..68815
                     /locus_tag="KRQ43_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741624.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            68822..69664
                     /locus_tag="KRQ43_001261"
     CDS             68822..69664
                     /locus_tag="KRQ43_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBH2741625.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            69725..72352
                     /locus_tag="KRQ43_001262"
     CDS             69725..72352
                     /locus_tag="KRQ43_001262"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH2741626.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            72566..72811
                     /locus_tag="KRQ43_001263"
     CDS             72566..72811
                     /locus_tag="KRQ43_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH2741627.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            73023..73340
                     /locus_tag="KRQ43_001264"
     CDS             73023..73340
                     /locus_tag="KRQ43_001264"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH2741628.1"
                     /translation="MSKKHKKYSKELKLKAVNLYIKEGYSSYKIAEMLNIRSKTQVQN
                     WIKDYKNKGKTAFNEETRGRFKNISLENDNRKFKSVEEELKYLRMENEFLKKLSTLLD
                     KSK"
     gene            73367..>74182
                     /locus_tag="KRQ43_001265"
     CDS             73367..>74182
                     /locus_tag="KRQ43_001265"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH2741629.1"
                     /translation="MSRKYSISSMCKLIGVSRSGYYKWLSYSKKSSDRGIKDRIIKDY
                     IIEIHKKYRGTYGRKRICTYLNKILDSPINHKKVYRLMKELGIKSIIRKKVYRRKFKS
                     YEVYDNILNREFRANQPLEKICMDITYIPIGKKFLYMNVAKDLFNGEIVAYEISTKMD
                     TKLVNKTVNQLINMNLAKDCILHTDQGSQYTSRSYSKRLKDNGIIQSMSRRGNCWDNA
                     PIESFFSHFKSELIYLIDTTDPKEMISLINDYIYFYNNERIQLKNGMSSIEYRT"
BASE COUNT        29517 a         7810 c        13605 g        23250 t
ORIGIN      
        1 aaatttatat gcttaattaa gataattttt ccaataatca agataatttt tttcattagt
       61 atgtatgata gatgcatcaa acaatataac taatatgtta gaaggttata tgtaattaat
      121 ctcagtgttt atatagaata gcatttgtag catttattat agttgtaatt actacttata
      181 tcatagactt gaatagtcta aaaaaataga ctataatatt tttatagact aaagaaaggg
      241 ctgataagat ggacatagca aaactaattt taaatcctgc aaggcttcgt atcttacaat
      301 atattcgact tcatggcagt gctcgcacat ctgatattgt aaagtattta aatgatattc
      361 ctcgtgcaac agtttatcac catgtaaaaa ttttagaaga gaacaatatg attgaagtaa
      421 ttaaagaaaa tcgtgtgcgt ggtactattg aaaaggttta tgcactaaag gaatatacaa
      481 catctatgga aggagagacc ttcgttgcac tttctacagc attttatgta ggtctgatgc
      541 aggaaatgaa tgaatacttt agcagaaaag agcaagacca taaaaaggat aatgtatttt
      601 tctcttcagc attactatat atgagtgata atgaatatga aaatcttctt aaaagtatag
      661 ctgatttatt gaaaccatat atagaacaaa agcctaaatc aaatctaaaa cttagaaaac
      721 tttcaattat atcttctcca cctgtggttg ataatgataa aacaaaataa catgaatctt
      781 atttttataa aaggaggttg tatatgaaat ttcatgaatt tggagataaa aacaaaccac
      841 atattatgtt gattcatggg ggagggaatg cgtggtggaa ctatttgcga caagcagaag
      901 ttttgtctaa caactatcat gtgatacttc ctacattgga tggtcatgga gaagaatatg
      961 aaacaacata catttctaca gaggatacag cagataagtt gatatcatat atagatgaaa
     1021 attgcagtgg acatcttttc gctttgtgtg gggtatcact tggtggtcaa attgtcatgg
     1081 aacttttatc tcgaaaacct aatattacta aaaaagcaat tattgatggt agtatttgct
     1141 acccaagacc tcttatggca aggttttgta ttgctggtat tcgatttttt ggaggacttt
     1201 tgtttagtga gaaggcttgt cgctttcaaa ttgctatgat gccaaaattg ttacctgaaa
     1261 atatgcaata tccagatgaa ataaaagcgt attatatgac agatatgcca catgtaagaa
     1321 aagaaacatt ctataatatg tatcgtactt atatgatgaa ctatacactt aaagagaatg
     1381 ttaaaaaaac cacagcacaa gtaatgtact ggtatggaga aaaagaaatg aagtgcgtta
     1441 aaaaatctgc aaaaatgttt cagtcttatg taccctcttg tgagatttat gaagctaagg
     1501 gctataatca tgggtattta tcgctttatc ttccaaatga atggttggaa attgcagaac
     1561 catttttcca aaaggaataa aggtgttagg tgattattgt ataattattg ctgttttttt
     1621 atatagtaaa taaattaggt ataaatataa aaaagttatt ttagttaata tattagtgaa
     1681 agcttaatag gaaaattata aatagattaa aggtagcgcc tatataaata gttgctacct
     1741 ttttttgctt gtaaataaat gatagataag aaagtttact gacaaatcac tgactaaacc
     1801 caattttctt acattgaaag ccttaatttt acttgtttta aataaattta caatttcttg
     1861 ttataaaata ctaaattttg ttaacaatta taattagcat ttaatttata ctggaggttt
     1921 atatgattaa tgtaagaaca gatttagctt tagaagctag tgaaatgtgt gaaaagtctc
     1981 aagaaggaag tagtattcct ggtgtaaaaa tagaaactaa agaattagaa aattgcattg
     2041 taactaaagt tgaagtaata gacaggcaag gcgcagagat aatgaataaa gatataggaa
     2101 agtatataac tctggaaagt aatcttatga agtttgatga tgatgagtcg agagaagaaa
     2161 tgataagtta tttaaaagag gagttagtag atatatttgg ccaagacaaa aataaaaaaa
     2221 ccctggtaat tggtcttgga aatagaaata ttacttctga tgcgttagga ccaaagagtg
     2281 tatcaaaaac acttgtaact agacatcttt ttaaaaatta taataaagac tatgatgatg
     2341 atttcactga ggtatcagct ttaagcccag gagttatggg tgttactgga atagaaacta
     2401 gtgaaatagt aaagtcattg gttgaaaaag taaaaccaga tagagtagta gcaatagacg
     2461 cattggcttc aagaaaaatg gaaagagtaa actctactat acagatatca acagcaggaa
     2521 tatcacctgg tggaggtgtt ggcaatacta gaaaatctct aactaaagaa actttaggcg
     2581 tggatgttat tgcaataggc gttccaacgg tggttgatgc agcaactctt acaatagatg
     2641 tcttagatat ggcaatagac aatttaatag ctcaatcaga agaaacagaa agtttttatg
     2701 aaatgttgaa aaaacttaaa gaagaagaaa aatatcatct aataaaagat tcgttagacc
     2761 catatgacaa gaacttaata gtaacaccaa aggatataga tgatacaatc gaaaatctat
     2821 ctataataat aagtgaaggc ttaaataggt ctttacatcc aggtagattg gtataaaata
     2881 aggaggagca attatgttta aaaaatgcat taaagtagta accttgactt ttatattagc
     2941 atgcatttta ccaggaaaat cattagcttt gaatcaggat gattttttaa agtttttagt
     3001 aaattcatct tatccagaag ctaaagtcga aggaaatgat acagaaaata aaaagaataa
     3061 taaaaataaa gaaacaagca aagaaaataa ggaagaaagt aaagaagaaa acactaaatc
     3121 taaagatgca agtaaagttg ataataaaaa agagagtgaa aaagaatata taaaacttta
     3181 tgttggtaaa gaaaatgttc cagatattga gtcaaaaaat tcagacacaa ctgaaactaa
     3241 cacaacatct agttcagatt ataaggatga tttaagagta accaaagaaa atccaagaat
     3301 tttgatatat catactcatg gatgtgagac ttattcaaat tcacctgatg gaaattatca
     3361 ttcaagagat aagaaaaatt cagtaatgga agtaggaagt gcattaacta gtgctttaga
     3421 tagcaaagga tggggtgtag tccatactac taaataccat gactatccat cttataataa
     3481 ctcttatgca agtagcttaa aaacaataca aagtatatta cctaaatata actcagtgga
     3541 tatagcgata gacttacata gagatgctag ggatttaact aatccagcca ctaaggaaaa
     3601 agaccattta aaatatacaa ctatgataaa tggagagaga gtatcaaagt tcttctttgt
     3661 tgtaggaggt aaaaatacaa atagaaaaca acttagagct ttagcagaag atataactgc
     3721 ttttgctgag aaaaagtatc ctggtctagt atctccaata gtagaaaaag actatgctag
     3781 attcaatcag tttgcagtta agaatcatat gttagtagaa atagggaata acgcaacaag
     3841 tgtagaagaa tctaaggcta ctacaaagta tttagccgag attttagatg aatattttaa
     3901 acaaaaaaat tagagcttta agttataatt aggagcatgc taaatgagcc gattagaaaa
     3961 aaatatagaa agtaaaagta aactaagaaa atacaagtat attatgagaa tcttattttt
     4021 gattactatg attataggta catcagtttg tgtatttata gtagacagta atgcaaaaag
     4081 tatgctagga atgaaacaat atgattttcc aagtattaaa tttgatataa caaaatttga
     4141 ttttgacata ccaaattttg atatacatga aatcataaaa aaatttaata agtagtaata
     4201 agtgaataag gtttattgat taaaataagc cttattttag ttatatattt ttaatgtata
     4261 aaataaaaat tcattaactg tattttatag gatttacttt aagtttacga tattatataa
     4321 tatttagtgt tagacttgat aatccacata taatgtggat aattttgttt agtgccaatt
     4381 agtttatatt caaaaatttt aaatttggta tataaagagt ttttagataa tgtaaaataa
     4441 taactataag aataatcaag aggagggaat tttaaggtgg acaataaaca aagtagaact
     4501 agaaatttta gtataattgc acatatagac catggaaagt ctaccttagc tgatagatta
     4561 atacaacaaa ctgggcttgt tagtgaaaga gacatgaaaa gtcaattact tgacaatatg
     4621 gaccttgaaa gagaaagagg aatcactata aagcttcaaa acataagatt aatgtataaa
     4681 gcgaaggatg gaaatgaata ttatttaaat cttatagata cacctggaca tgtagacttt
     4741 aactatgagg tatcaagaag tttagctgca tgtgaaggag cactattagt agttgatgca
     4801 gctcaaggtg ttgaggcaca aactttagcc aatgtttatc ttgctataga ccaagattta
     4861 gaaatattac caataataaa taaaatagat ttaccaagtg caagaccaga ggaagtaaaa
     4921 aatgaaatag aagatttaat agggcttgat tcaagtgaag ctcctcttat ttcagctaaa
     4981 actggtttaa acatagaaga tgttttagaa gatattgtaa aaaatgttcc tccacctaag
     5041 ggagataatg aagctccatt aaaggcatta atattcgatt cttactatga tgcttacaaa
     5101 ggtgttgtag cttatgttag agtatttgaa ggaactgtta aaaagggtat gacaataaaa
     5161 atgatgaata ccaataaaaa gtttgaggta actgaagttg gtgttatggc tccaggtcaa
     5221 actgaactta gtgaattatc agcaggtgat gttggttata ttgctgctag tataaaagat
     5281 ataagaagtt gtcgtgttgg tgatacaata acagattcaa ataatcctac agaagaacct
     5341 ttaccaggat acaaaaaagc tactccaatg gtatattgtg gtatatatcc aggagaagga
     5401 gaaaagtatg agaatgttag agatgctctt gaaaagcttc aagtaaatga tgctgcactt
     5461 gaatatgaag ctgagacttc agcagcacta ggatttggtt ttagatgtgg tttcttaggt
     5521 cttttacata tggagataat gcaagaaaga cttgagagag aatttaacct tgatataatt
     5581 actacagctc catctgttat atatagagtt acaaaaatgg atggagaggt tgtaatgata
     5641 caaaatcctg caaacttacc agaaccatct gagataaaga tgatagaaga gcctatagta
     5701 aaaggagata taatagttcc taaagactat gtgggtgttg ttatggagct ttgccaggaa
     5761 agacgtggaa atatgttaaa tatggaatat atagatgaga gaagagtaat gcttcactat
     5821 gaccttcctc tcaatgaagt tgtttacgat ttctttgatg ctttaaaatc gagaactaga
     5881 ggttatggtt ctcttgatta tgaggttaaa ggttatgtag catctacact tgtaaaactt
     5941 gatatattaa tcaataaaga acaagtggat gcacttagtt ttattgtcca tgagacacgt
     6001 gctttcccta gaggaaaggc aatgtgtgag aaattaaaag gagaaattcc aagacatcag
     6061 tttgctatac ctatacaagc tgctgttggt aataaggtta ttgcaagaga aacaataagc
     6121 gctctaagaa aagatgttct tgctaaatgt tatggtgggg atatatctcg taagaagaaa
     6181 cttcttgaaa agcaaaaaga aggtaagaag cgtatgagac aaattggttc tgttgaagtt
     6241 cctcaaaaag catttatgtc tgtacttaaa ctagatgaat aaattcttat aaatttagat
     6301 aaatatattt aaaagctaga gtgattttag aattatttct aaattaatct agcttttttg
     6361 tggtatattt taagtaaact catagagaat ataagtaaga atatattaaa gaagaataaa
     6421 aaggtgatat ttatgattaa tatagaaatt cctaaaaaag tagactatat aattaaagaa
     6481 ttagaaacga atggttatga agcttatgta gttggaggat gcgttagaga ttgtttatta
     6541 gaaagagttc caaacgattg ggatataaca actagtgcta gaccagaagt ggtagtagaa
     6601 ttatttgaaa aaacaattcc aactggtata caacatggga ctgtaacagt tatgattgaa
     6661 catgaaccat ttgaagtgac aacttataga attgatggaa attatagtga tggtagacat
     6721 ccagattcaa tagaatttac aaataacata gttaaggact tgtcaagaag agattttact
     6781 atcaattcaa ttgcatacaa ttcaaagaca ggattagtcg acccatttaa tggctatgaa
     6841 gatatacaaa ataagtatat acgttgtgtt ggaaatccag tagatagatt tgaagaagat
     6901 gcacttagaa tgcttagggc agttagattt tcagcacaac ttaattttaa aatagctgaa
     6961 ggtactaagc aaagtattca taaaaaagca gatttgataa aaaatgtttc tatcgaaaga
     7021 atccagacag agtttaataa aatattagta tctgattcat ctaaattaaa cttattaaaa
     7081 tcaacaggtt tgttgaaatt tataattcct gaaatatgtg aattagaaga tgttactcaa
     7141 cacaatccat atcacatcta tgatgtacaa aaacatactt taatatctac agaagtaatt
     7201 gaagatgaac tgtatttaaa acttacaatg ttgtttcatg atttaggtaa aaaagtaact
     7261 aaaacaactg ataaaaatgg tgttgaccat ttttatactc atagtagaga atctgtaaag
     7321 attgcaaaga agattttgag aagacttaag tatgataatt atactattaa taaagtttta
     7381 atattaatac aatatcatga ttatagaata gaacctaaaa ggaagataat taaaaagtta
     7441 ttaaataaac ttgaagatgt tgaattattt gaagatttaa taaaagttaa ttgggctgat
     7501 acacttgcca aaaacccaaa gtatgcaaaa caaaagatat taaatcttat tgagtgtgaa
     7561 aaagaattta aacatataat aaatcaaaag gagtgcttta atcttaaaga tttagctatt
     7621 aatggaaaag atttgatatc tataggtata aaaccaggta aagatatagg acatatttta
     7681 aataagatgc ttgaaatagt cataaataat ccagaattaa atgaaaaaga aatactaaaa
     7741 gaaaaagcat taaatatata tacattttag attcaaatat aaaaaattta attactttaa
     7801 aaaattatag aagaaaatac ttatttagat aaaataaata atttttagag aatattttag
     7861 aagttacgat tgtatgattt ttaaacgcat agcatttact ctaggactat agactaatat
     7921 aaaaaaaaac tttgggaata ctaaaaccat aaatttataa aattaatatt ttatatactg
     7981 taaaacagtg aggagggaca gtatgcatac tcaactacaa aagactattg gtctttcagc
     8041 ggctctttct actgttgtag gtatggttat aggttcggga gtttttttta agccacaagc
     8101 aatatacact acaactaatg gagctccagg tctaggtatt atagcgtggc ttttaggtgg
     8161 ttttataaca ataactgctg ggcttacagc tacagaaatt tcagctgcta taccaaaaac
     8221 tggtggtatg atgatttata tcgaagaaat atatggagaa aagttaggct ttttaactgg
     8281 atggatgcaa actgtattat ttttcccagg tacatcagca gcattaggag taatatttgc
     8341 tcaacaagca tctgaacttt taggaatgag cccaaataat atggcaaatg tacttcctat
     8401 agcaattgga gttatactat ttttagcgtt attaaatata ataggttcat ccttaggagg
     8461 aaaagttcag acagtagcca ctattggaaa gatgatacct ttaattttaa taatagtctt
     8521 tggatttatt aaaggtcaaa gtagtgaagt attaaatcca tttgtaggag atggtgtaaa
     8581 tgcatcaaat gcacttggac aagtattaat agctactttg tttgcatatg atggttggat
     8641 aaatgttgga gctatatcag gagaaatgaa gtctccagag aaagatttac caagagcaat
     8701 agttggtggt ttatcattag ttatggcagt ttatattata ataaatatag cttatctttg
     8761 ggtagtacca gcaagtgaat tagcaacagt tacttcccca gctacattag tagcaacaag
     8821 attgtttgga aatataggtg gaaaagtaat aactgtgggt atattaatat cagtatttgg
     8881 gacattgaat ggatatttat taacaggttc aaggatacct tatacattag ctgaaatggg
     8941 aactttacca gcatctaaaa ctcttttaaa agtaaattct ggaggttctc ctgtaaattc
     9001 aatactactt ataactgtgt tagcctgtgt atatgcatta tctggtcaat ttaatctttt
     9061 gacagactta actatatttt caatatgggt attttatgta ttgactttta taggtgttat
     9121 gaggcttaga agacaaaagc cagatttaca cagaccatat aaagtccctt tatatccaat
     9181 aataccaatt atagctatac taggtggact gtttgtaata ataaatcaaa tattgacttc
     9241 aacaattata tctttaggtg gaatatttat aacactatta ggtttaccag tttattatta
     9301 tatgaaaaaa agataactac ttaatttaag ttagataaat ttgggtaaag gtgaaaatta
     9361 acttttatcc aaatttttta tactgttata caatataagc attatatatt acttgatgtg
     9421 ttattttgtt tgatttataa tttagtaatt gatgctttaa gataatttaa gaaatgagga
     9481 ataaaaaatg ctaggacttt atgtacatat tccattttgt gtgaaaaaat gtaagtattg
     9541 tgattttaat tcttataaaa tggacataga ttcaaaaaaa agatatatag aagacttaaa
     9601 aatagaaatg aaattatata gtaataaatt atataaagat aataaatata aaaataaaga
     9661 atgctgtagt ctaaataaaa atgacaaaat aacgagtata tttgtagggg gaggtacacc
     9721 tagtatacta acatctgatg aaataagaga agtatttata agtataaaag aaatgtttga
     9781 tatagatgag aatgcagaaa taactataga gtgtaatcct gggacattaa cattagaaaa
     9841 attaaaaact atgaaagaga ttggcataaa tagacttagt atagggctac aggccattca
     9901 agaaaagcat ttgaatttta taggaagaat acatacttat gaagaatttg agaaaaacta
     9961 taaagatgca ttaagtgtag gttttaaaaa tattaatgta gatttaatgt acagtcttcc
    10021 aaatcaaact ctatgtgact ggaaggaaac tcttgaaaaa gttgtacact taaatccaac
    10081 acatatatca gcgtattccc ttatactaga agaaggaact gaactatata atatgtatga
    10141 aagtaataaa tttgagctta tagatgaaaa tgtagatata gaaatgtatg agtatacaat
    10201 aaactactta aagtcaaaag gatataatca atatgaaata tcaaattact caaaagaagg
    10261 ctataattgt gagcataata ttttatattg ggaatgtgaa cattatatag ggattggagc
    10321 aggagcttct ggctatatta atgagaacag atacaataat gtagaatctt tagaagatta
    10381 tcatttaagt ttggtaaaaa gagaaaaacc aatacaagaa aatgaaattc tttctgagaa
    10441 agatatgata gaagaaaaga tatttatggg gcttagaatg aataaaggca taaaatttga
    10501 agattttaaa aaaaaatttg gaatagattt tagagagaag tataataagc aaatagaaat
    10561 gctattagct agaaagctta taaatcagag ctttgaaggt atacaattaa ctcaaaaagg
    10621 aagagaaata tctaatagtg tatttataga atttatggaa taatttttaa ggtgttgaca
    10681 aaataaattt ataatggtat ataatatata taatcttttt agcactcgaa cttagtgagt
    10741 gctaacagct aggaggtata ataatatgga attaaatgaa agaaaattaa atatcctcaa
    10801 agctatagtt aaagattata tagaaacagc tgaagctata ggttctagaa caatatctaa
    10861 aagacatgat ttaggtgtta gtgctgctac cataagaaat gaaatggctg accttgaaga
    10921 attagggtat ttaattcagc ctcatacttc tgcgggtaga gttccatctg aaaaaggcta
    10981 taagttatat gtaaactctc ttatgagtaa aagcgaattg gatgataatg ataagattct
    11041 tattgaacaa tgtatgaatc ataatataaa tcatataaaa gaattgattc atgaaacctc
    11101 taagctatta tcgcaactaa caaactatac aactgtagca gttactaaga gtttaataaa
    11161 tcaaagtgtt ataaagcaca tacagttggt tgctatgaat gacaataata ttttacttat
    11221 agttgtaaca gataaagggg acttaaaaaa agctaacctt acaactaatg tatatttaga
    11281 tcaatctaag ttaaatttga tttctgataa tcttacaagg aagcttttag gtaaaagtat
    11341 aacagatttg gatgataatc taattgcttt tattaaatac gaaataagtg agtattctgg
    11401 acttatagat gagcttttaa atgctttgaa ctcaaatatg aaagaagaag atttttctct
    11461 atcattaaat ggagctacta acatatttag ttatccagaa tttaatgatg tattaaaagc
    11521 aaagtcattt ttaaatatgt tggaaaaaaa ggaaacaata gctgacataa ttaaatcaaa
    11581 gggaatacaa aaagacaatc taaatataat aattggtagt gataatgatt gtgaactggc
    11641 acaggattgt agtatagtta cagcaactta taatgtagat agagacttgg ttgggcgaat
    11701 aagctttata ggccctacca gaatggatta tgctagaatt tactctataa taaattatat
    11761 gagtttatta attaatagaa agtaaagaaa ttttaaattg cgaggtgtaa agtcttggat
    11821 aaaaaaaatg agcaacagga agtaagagaa gaaaatgata cttctattaa ccaagaatcg
    11881 gaaactcaag tagagttaga agaggaagtt gttaatgaag aatgtgaaac atcaagtgaa
    11941 aaaactgatg aaaaagaagt tgatgatgaa aatgtaacag atataaattc taagttagca
    12001 gaaaaaaaat tgcaggatga gttggatgaa ttaaatgata aatatcaaag acttcaagcc
    12061 gaatatgcaa actacagaag aagaactcaa caagagaaag agacaatagg cgtatttgca
    12121 aatgaaaaaa taataactga gttgatacca gttatagata gtatggaaag agccttagat
    12181 gcatgtgaag ataaggaaga tactatgtat aagggtataa gccttgtaca taaacaatta
    12241 atagacactt tggtaaaatt tggagtagaa gaaatagaag cagaatctaa ggaatttgac
    12301 cctaatctac atctagcagt tatgcaagaa agtgtagatg gagttgaagc aaatcaaata
    12361 gtaatggtac ttcaaaaagg atataagcta ggaactaaag ttgtaagacc ttcaatggtt
    12421 aaagtttctt gctaagtata aattaaaggt taaattattt aacctaatat aaaatattaa
    12481 aataagtaaa acttaattat ataattactc gaggaggatt ttagtcatgg gaaaaataat
    12541 aggaatagat ttaggaacaa caaattcatg tgttgcagtg ttagaaggtg gagaagcaca
    12601 aataatagca aatagtgaag gtatgagaac tactccatca gtagtagcat ttacaaaaga
    12661 tggtgagaga atagttggag aacctgcaaa aagacaagca gttacaaatg cagataaaac
    12721 aataacttct ataaaaactc atatgggaac tgattataaa gtaaatatag atggaaaatc
    12781 atatactcca caagaaatat cagcaataat attacaaaaa ttaaaatcag atgcagaaag
    12841 ttacttagga caaacagtaa cagaagcagt tataacagta ccagcttact ttacagatgc
    12901 tcaaagacaa gcgactaaag atgctggtag aatagcaggg cttgatgtta agagaataat
    12961 aaatgagcca acagcagcag ctcttgctta tggtatggat aaattagacc aagaaaagaa
    13021 aatattagta tttgacttag gtggaggaac ttttgacgta tctatacttg aaataggaga
    13081 tggaactttt gaagttttag ctacagctgg taacaataga ttaggtggag atgactttga
    13141 ccaaatagta atagattatt tagcagatga atttaaaaaa gctgaaggtg tagatttaag
    13201 aaatgataaa atggctcttc aaagattaaa agaagcagca gaaaaggcta agaaagaatt
    13261 atcatcaaca atgagttcaa acataaactt acctttcata actgctacag cagaaggacc
    13321 aaaacactta aatatagatt tatcaagagc taaatttgaa gaattaacta gaggtttagt
    13381 tgaaaaaact atggaaccaa ctaagacagc tttacaagat gcaggacttt ctacaggtga
    13441 tatagatgat gtattattag taggtggttc tacaagaata ccagcagtac aagaagctgt
    13501 taagaagttt ataggaaaag aacctcataa aggtataaac ccagatgagt gtgttgcagc
    13561 aggtgcttct atacaagctg gagttttagc aggggatgtt aaagatttat tattactaga
    13621 tgttactcca ttatctcttg gtatagaaac tatgggtaat gtaatgacta agataataga
    13681 aagaaatact acaataccaa ctaagaagtc tcaaatattc tcaactgctg ctgataacca
    13741 aacagctgtt gatatacatg ttcttcaagg tgaaagaagt atggcttatg acaatacaac
    13801 tttaggaaga ttccaattaa cagatatacc accagcacaa agaggaatac ctcaaataga
    13861 agttactttt gatatagatg caaatggtat agttaatgtt tcagctaaag atttaggtac
    13921 aggaaaagag caaaaaataa ctataacatc aaacactaat ttatcagaag cagaaataga
    13981 gcaaaagata aaagaagcag aaatgaatgc agaagctgac aaacaaaaga aagaaaaaat
    14041 agaagcattc aatcaagctg aatctactat atatcaaact gaaaaaactt taaatgaact
    14101 tggagataaa ataagttcag gtgaaaaaga ggatatagaa aaagctatag cagacttaaa
    14161 agctgtaaaa gataatcaag atgctacagc agaagaactt aagaaagcta cagatgaagt
    14221 aatgactaag ttccaaaaag tatctcaaga aatgtaccaa aaagcagctc aagaacaaca
    14281 agcggcacaa ggtgcagaac aagcacaaga caatggacct aaagatgaca atgtagtaga
    14341 tgctgacttt aaagaagtag atgaagataa ataagctata taatatgtaa cactaaatga
    14401 taattggaac atatatgatt tgtgaaaatc atatagatgt taaagatata tggacaatac
    14461 acatcataaa gaatataata tatcatagat tatataactt aaagtagaat ataagaatta
    14521 atgatagctt gtagtttatt attctacaag ctatcgtttt gtaaaatgaa ggtggtgtca
    14581 atttttgagt acaaaaaggg attattatga agtcttaggt atcagtaaag atgcagaagc
    14641 tcaagagata aaaaaagctt atagaaaatt agcaatgaag taccatccag atagaaatcc
    14701 tggagataaa gaggcggaag aaaaatttaa agagataaat gaagcttatg aagttctatc
    14761 tgatgataca aagagaaaaa cttatgacca gtttggacat gatggattaa atggtcaagg
    14821 tggttttggt ggtcaaggag gatttggcgg tcaaggcttt ggtggttttg aagatatgtt
    14881 cggagatata tttggtgaca tgtttggagg aagcttcgga ggtggaagag caagaagaag
    14941 agggcctcaa cgtggtgcag atataagaca gagtgttact atatcttttg aagaagctgc
    15001 atttggtaaa aagatgtcta taaaagtaaa tagaagtgaa gagtgtgaag aatgtaatgg
    15061 aactggagca aaaccaggaa catcaaagaa aacttgttca acttgtaatg gaactggcca
    15121 agttagaact gttcaaagaa ctccatttgg taatatagca agttcaagac catgtagtgc
    15181 ctgtaatgga actggagaag tgattgaatc tccatgtagt aaatgtcatg gaactggaaa
    15241 tacaagaaaa gttaagacta tagaagtaga tatacctgct ggtatagatg atggtcaaat
    15301 gataaaactt tctggtcaag gtgaagtagg agaaaaaggt gctccaagag gagacttata
    15361 tattgtagtt aatgttaagt cacatccact atttactaga gatggaaatg atatttattt
    15421 tgaaatgcca attacatttg ttcaagcaac tttaggtgat gagatagaag tacctacttt
    15481 ggatggaaaa gttaaatata gtgtgccaga ggggacacaa actggaactg tatttagact
    15541 taaagagaaa ggaatcccta gaattagagg taattcaaga ggagaccaat atgttaaggt
    15601 tgtagttgaa attcctaaaa aattaaacga taagcaaaaa gaactattga gagaatttgc
    15661 gaaggagtgt gggtcgaacg tccacgaaaa gaagaaaacc ttcggacaaa agatagaaga
    15721 tatgtttaag aaaaagtagt taaagtagcc aatatataat catatttttg aaatcttagt
    15781 tatttataag attgtcaaag gagatattat gatttttata ttggctattt ttgtataaaa
    15841 aataaatgtg cataaaataa aactgaatat aaataatttt ctgaaaaata cttgtcctaa
    15901 aatatataat gtgctataat ataatcaaat aaaagaaagg ggtgattcca gtgggaacgg
    15961 atgtggcact gccaaatgat gaagaaaact ttattgtaat atacaaaata aaattagata
    16021 cttttagtgc tagattaagt actggaaaaa ctcatgagct gggataatta ttgtaattac
    16081 ctagactcaa acttttagta gtaaaatagt aatattatat agacaaggta tctaattttt
    16141 aaatcttttg tatgagttaa aatttttata aagggtatat ctgattagaa tgtaattagg
    16201 gaaacctagt tgtgaattac ttttagtata tacatgtgta aagaaatatg tatatggtat
    16261 tggttattgt gctagatgtg tatgtaaagg aatatgtgtc tagttgggta tatgtaaaga
    16321 aatatactta taatctatga aaaattttta gtataaattg ctaaaacatt gagattgttt
    16381 tttatagaaa gttagtttat accaactaaa aatgtgctta agatttgttt gatgtttaat
    16441 tataaataag gttgtagata aaaaaataag taaagacaaa ggtttaaaat acttgcttta
    16501 aatatagttt gttttgaaca cttgccaaat taaaataatt aataaaatag acatcttctc
    16561 atagtaaaat atactgtgag aggatgtttt tgctttgttc ataaactttt atgaaaaatt
    16621 tgcatagtgt cacattttaa tatactatat atataataaa atatagataa aattaaatga
    16681 ttcaaaagag aaaggtgaaa agagatgtat tatataggtg tagacatagg aggaacaggt
    16741 atacaagcag gagtagttga taactatggg aagataattt ttaggtcaga gtgtaaaaca
    16801 gtaattgaaa aaggctttga aggaatactt aatgacataa aaataatgat ttataagttg
    16861 ttggaagata ataaacttac tatgagtgac ataaaatcta ttggatttgg tgttccaggt
    16921 tttataaata aagaaggatt agtaacttgt gtaaatttaa aatggaataa aaaagctttt
    16981 aataaagagt taaaaagaag atttccagat gctgaaattc atggagaaaa tgatgcaaca
    17041 gtagcagcac ttggagaagc aaagtttgga agtatgaaag gtgctaatgt tggagtatta
    17101 tatactttag gaactggtgt aggtggagga atagtaatta atcaaaaagt cttttctgga
    17161 gcacatggat tgggttcaga aataggtcat caaattatag gagaaaacta ttttaattgt
    17221 aattgtggaa ataatggttg tgtagaaact ttttgttcag caactgcaat tataaagtat
    17281 tctcaaaaac tgatagaaga aggagaaaag agtaggattt tagatttggc agagggaaat
    17341 ttagaaaatg taaatgcaaa gatggtgttt gatgcatata gagaaaatga tttagtggca
    17401 attaaagtaa taaatagatt taaagattat ttagcaaaaa cttttgcaaa cacaataaat
    17461 tctttagacc cagaaattat atctatagga ggaggcattt ctaaatctag cgatataata
    17521 cttgatggaa tagaagattt ggtaagaaaa tttgtattat acaaaacaga agatatagct
    17581 acaattacat gtgcaacttt aggttcagac gcaggaatta taggagcagc ttttttataa
    17641 tgtaaatgaa ctgcttattg gaggcgtgat gatatatggg taaaacaaat gctagaagaa
    17701 cgcttttttt gatagcaata ggttcaggaa ctatgctgaa tcctcttaat tcttctatga
    17761 tttcacttgc tttacatagt atacaaaatg attttcatat tagttttaca actgtatctt
    17821 ggattgtttc agcattttac ctagctagtg ctattgcaca accagtttca ggtaagatag
    17881 gagatttaat aggtagaaag gtcttatttt tgagtggttt gatgcttgta attttatcag
    17941 catccatagt accacttgtt caatcattct ttatattgat ttttataaga gtaattcaag
    18001 caattggaac aagtacccta tatccatctg gagttgctct tatacaaaat aatataaaag
    18061 aaagacaatc ttctgcatta gcagttctaa ccatttttgc ttcaactaca gcaggattag
    18121 gtccgacact tggaggatta ttgttggact taggaggatg gcatgctata tttcttgtaa
    18181 atatacctgt tgttttggtt tctatatgct tagggtattt tttattccca aaagaagtaa
    18241 aagaaaagaa atctataaaa gaaactttaa aaaatgtttt gtcaagatta gatattattg
    18301 gcatacttct attttcaatt gcaatgattt ttatattact atttttgcta tctatgaagg
    18361 aatcttttaa cttagaacaa cttgtatttg gtataatact gatgtgtctt tttatttggc
    18421 atgaattgag aacaaaattg ccatttatag atattaagct ttttgtaagt aatcctaaat
    18481 tgtcaaaagt ttacttgcaa tttattatat taaatttctt taattatatt ttgttttttg
    18541 gtcttcctag ttattttcaa gatgccttac attatagtgc aaagtcgact ggattattta
    18601 tgctatttat gtctggtata ggtatattta tatctccatt aactggaaaa tggatagata
    18661 aatctggaac tagatttcct cttgttacat catcaatctt tatgtttatt agtgcagtac
    18721 ttctttcagt agtttttatc catatacctg taataggaaa gggtattata ttatcattag
    18781 caggtattag ttatggagtt ggtaatgtag ccctgcaatc ctctatgttt gaagaaagtc
    18841 ctcgtgacag tatagggaca gcttctggtc tgtttcaaac tagtcgttat ttaggttcta
    18901 ttttagcaac tgttttactt ggaatggtat ttgaaggaaa tataacatca gaacaatttc
    18961 agatattagg ttatgttatg gtggtcttag gtacaataag ttttttatta aattttatat
    19021 taaagaaaga attaagaaaa gtagaatagt ggatttatgg atttaataag tctaataact
    19081 gataagttta aaaatattgt ttgtaaaaca taactggttt gatatttatt aattctaagt
    19141 tttgaagcat agagtactcg ataagtatac aatattttga attaaaatta agcagaaatt
    19201 tgaactagtc tttcaaatct ctgcttaatt tagtagttaa atttttttat agagaaaata
    19261 agatttgaca cttagataaa aaatcattgc attttcaaaa ttctttaaat caaacccaag
    19321 tatctcatta atcttttcca atctatatac tagcgtgttt ctatgtaaaa acatactagt
    19381 agatgtctta gaaatattta aatcattatt tataaatttt attcctgtat atagaagttc
    19441 ttcgtcaata gatttaatct tattaaaatc tattaattta ttgagtatat tatcctcatt
    19501 aattaaatct aaagttttat atctaataag gtcaaacaaa tttaaaaact tattttcagc
    19561 attgtctttt ataatatgag gtagtaaatc agaacataac tgtaatctaa aataaaaatc
    19621 agctttacta tctaattcac caagataaaa aatataagta ctttgataag tttcagtttc
    19681 aattatattt tgtgtagtta cattaatatc taaattatat ttagaattta ctataaaaaa
    19741 accattgtgt tgtattatat ttatatcttc aaataaatta taaaaaatat tttttaggta
    19801 ttcaaagtct atatgagatt ggtaaattaa ataaaagttg ccttttaaat tatcaagatt
    19861 atttttatct agaaaatcaa taacataaat agcattattg aaagtaacta aatggctact
    19921 agcatctaac ttttggtttt catagggata gatatttatt tttttattaa gctgtctttc
    19981 taaaaaatct tttaactctt ccataaagtc tccttaaaaa taagattata ttcttatctt
    20041 atagctaaag tagtttcttt gtcaaatatg tgtactctac tattgtcaac tgaaagtgtt
    20101 aagtcatcac caacattaat tctgttttta ctgtcaaatc taattgttat cgtattttcg
    20161 cctagtttta agtgagcata agtttctgct cccataagtt cttttatttc aattcttgat
    20221 ttaaaacaag tatctggatt agatttaata aaagtatctt ctacatgaat atcttctggt
    20281 ctgataccta taacaacttc attattaata taattgtctt ttattaaatc atagtgtttt
    20341 tctttattca atttaagctt aatatgttca ttttgtgcat aaattttatc attttcttct
    20401 attaatatta catcaataaa attcatctgt ggtgctccaa taaatcctgc aacaaatata
    20461 ttagctggat aatcgtatac atcttgtgga gttgcaatct gctgaactac tccatccttc
    20521 attactacga ttctatcagc catagtcata gcttcaactt ggtcgtgtgt tacatagata
    20581 aatgtagttc caagctgttg gtgtagctta gttatctctg ttctcatagc agttctaagt
    20641 tttgcatcta agttggatag aggttcatcc attaagaata ccttaggatt tctaactatt
    20701 gcacgtccta aggcaaccct ttgtctttgt cctccagata atgttttagg ttttttattt
    20761 aaaagaggta gtaagtctaa tattttagca gcttctttaa cttttttgtc tatttcatct
    20821 ttaggcaatt ttctaagttt aagtgcaaat gccatgtttt cgtaaacaga taagtgggga
    20881 tataaagcat agttttgaaa aaccatagct atatctctat cttttggttc tatatcattg
    20941 acaagtttat ctccaatgta tagttctcct tcagagattt cttcaagacc agcaatcatt
    21001 ctaagtgtag tcgatttacc acaaccagat ggtcctacta aaacgataaa ttctttatct
    21061 ttaatgtcta tatttatatt ttttactgcg ttaaatccat ttgagtaaag ttttgatata
    21121 ttttttaaaa ttacttctga cataatattc tccttgatat ttaaatttta atgatatagt
    21181 atcaaatttt tttattatat taaatgtgta aaatgactaa atgtatttgt ttaatatgta
    21241 tatttaattt ttagcaaaga ataaaactaa cagtaaaata tatttaaaaa attaaaaaac
    21301 aaaattaaat ttattatcaa aaaatcattt tatgatatgt tttatttttt atattacaaa
    21361 tagagaataa tgaattatac tagaaagtag gaggtgaaaa tatgagcaga atttcaattt
    21421 ttatggagtc atgtaatggc aaatttccaa atgaaaattc aatgttgtca gtttccttta
    21481 taaaaaatat tttaaatgca gaaaacaaag attttgctaa aaatatattt aactatgggg
    21541 aagaaagaaa aaacaataag caaataaagg atataaatac agccatctac ataccaaatc
    21601 ttataagaag caaaaatgag ttgcttgttg atggagatat aatattcaat ataagttttt
    21661 ataattattc tatgttcagt aaattataca atggaatttt aaaagtaaag gagctagaat
    21721 ataaaggtta tagatttaaa ataaaaaata taaaaataca taaagaacac gagataaaag
    21781 aaaatggtgt tatatttaaa actatgtctc ctataatagt aaagaataaa gaaggtaaat
    21841 atttagatgt agaagattca aattatatag aatgtttaaa ctatatagct aatctaactc
    21901 tggagagtat aagaggtagt gggcttagaa agccattgga atttatacct cttaacttca
    21961 aaaaaagagt gttaaaagaa aagattcgtg gatttaaagt gagagaatat tactatataa
    22021 atgcttatgc aggaacattt tttttaaaag gaaatatgga agatttaaat gcactgtata
    22081 aaatgggaat tggatataga aggacggaaa atgcaggaat ggttgatata ttaaagtagc
    22141 gaggtgagag aaataaaagc taaattttat agatcaggtg atattgtaag agatattggc
    22201 attgtttact tttatgaatt actaatggat ttaaaaaacg aactagaaaa aaatgattat
    22261 aagctaaaat ttacttgtga gttaaataga aattatttat ctttagaatc tgcagaatat
    22321 atagacccta agtatatatc tgattatata ttagaaaatc aactttttaa ggtatttaaa
    22381 aatgggaaaa aggaaacctt agaaaaaata tttagtaata tagataattt aacgtatgta
    22441 aattttattg aagaattaga taaatcttct gcaactgaga aacaaaagga agggattaaa
    22501 aaagatttta aaaacagaag atttccatat gttagaaata gtggtaagta tggattaaac
    22561 acgagtttag aaaatatgga aacaaatgta aaaagaatag tagatactgt aattaaatca
    22621 aatatagaga tagatgaaat agataaactt gatttgacac aatatgaaga aaaagatagt
    22681 gtatgtaatg tttgtaatat aaataaaaca acaaaactag atattgattt aagagagcga
    22741 aaggactcta agtataactt tttatttaga ggtgcagaaa aatcaggctt taaaagaagt
    22801 ggacaagttg aaagtaatat ttgttttgag tgtgaatttt tcaacttaat gtgtctttta
    22861 tatataaatt taaaaagacc aatggttttt gcatatacga atgatttaag ggaattagca
    22921 tttttaaatc ataagataat gcttaaaaga aagatgtatt cagataaatc attttataaa
    22981 aaacttttgc atgaaaaaat aagttcgatt agactatata ggtttgatat tgatacgaat
    23041 aaaggtataa ttctaaagtt tgactctatt atagagtata aagaattatt aaaaaaaatt
    23101 gaacttatag atattataga taattataat ttttcaagag agccagggaa tactagaaat
    23161 ttgggtaaaa aaatgattga taatgggaat ttatcaaatt taaaagaatt attacttgat
    23221 aatataagtg ttttaaggca actaactgga acttctcgag aaatggattt tgtatctagc
    23281 tcatataata tcggtttata tataaaattg tgttggattg tagatggagg ggaggagtat
    23341 aaaatgaaaa actatatgga aagtaattta atatattcaa gagtaggtaa agacttattt
    23401 aataaaatga cagatgaatc cagaagaaaa aatttttcta tgaaagtgat tcaactactt
    23461 aagtctaatg atagaactca gctatttcaa actataatgc atgtgttagt ttctaatgga
    23521 atcttaatag gagaagggtt tgtagaaggt ctaatgcaga gttctgaatt agaattaaat
    23581 acgaatgtag gtctatttat tcaagaaatc atgaaataaa aaagggggaa aatttaaaat
    23641 gaatgaaaaa agagtaaaag gagtaacatt aactatactg acagaaagcc cagttccact
    23701 ttcatatgac caagggtatg gaaattatac accaataaaa aaagaacaat atagagaaaa
    23761 aatacatgca aaaactagta tagccacaat aacatatgat ttaagaagaa tgctccacca
    23821 agaatatggt tggaatttaa gtaatattat ttttgggaaa aaaggaaata tatatccatc
    23881 tattaagcaa aatgtaggat gtgtagatga aaatggatta gagactgatg tatttggtta
    23941 tttgatacca cttaaagata aaggttctat aagtaaggct tctccgctta gaataatacc
    24001 ttttaggtca ttaaattcat atagaggttc aacacagttg ataacaaata gaggtttttt
    24061 aagtagcgaa tttggtagaa aatattatga tgagaaggaa gaaaatgaag tacttagaga
    24121 tgaaaacttt ccaacatcac aagcattagc aatagaagag actttatcag attactacgt
    24181 ttatacaata acattggagc ttgatagaat aggagtagta gaagtagaag atggaaagtt
    24241 gcttttacca gaagaaagaa aatttatgag taaggagtta agagaaaaag cagtaaaaga
    24301 tatattagat gcaattactg tgtttacaag aaacataaaa cattcatcag tactgttaaa
    24361 accacttgca gtaatgggtg gagcttttga taaagttgta ccgttttttt gggatgatgt
    24421 agattataat gctgatagtg gtgagataaa tttagaggga gtcatagaaa ctatagaaag
    24481 ttatagcctt aaagaaagta acacaatact tgctatcaat gacaaattaa aaatttctaa
    24541 taaaaaggaa ttaaataagt ttaatttaag taaataccct gtaaaagaga ttaaaaatct
    24601 agcagataga ttggaaattg gagaagataa tatgtggtat ttaaaagagt aggaggtttt
    24661 ttgaattatg aaagtattac aatgtaaact taagcaacca actgctcact atagagaccc
    24721 aaaagtattt caaaatgaat atataagtac tttaaattta ccatctaaga ccacaataat
    24781 gggaatgata acgtatttat gtgatagaag attaaactct gatatagata taggaataat
    24841 tggaacacat catcatagag aactagaatt ttcaagagga gagaacattg atttttggaa
    24901 tgaatataca aatatgagaa aaggcaaaga taaagaaaag tttttgcttc aaggaaacta
    24961 ctatgattac tataaagaac ataaagctca aaatagcata ttaaactatg aagttcttaa
    25021 agaagtagaa ctgactatat ttatttcttg caaggatgat gaagaacttg aatttattaa
    25081 aaaaaagctt gaaagtccat gtaaatatgc aaatttagga agaaaagaag attttgtaat
    25141 accaagtgaa aaagggtgtt ttgtgaaaga agttgagtta aaagaggtta tgcctatgaa
    25201 tactcgtgat gctataaaag aaaatataaa attaaagaat acatatgtaa gagttgactt
    25261 aagagataaa gagaatgtcg agactataat aaatcaaggt gtattgattg cattacctta
    25321 taaatataaa gatttagaag caaatagaga tgatagagtt tatgagtttt gccattatat
    25381 atatgttgat aatgatggta tatatcctaa aaatattaag gtaaatgtat gtaatgtatg
    25441 tattgataca aaagaagttt ttacatggct ttaaattatt ttgaaagata ggtgtttatc
    25501 atgaaaaata tcatgcaaaa agaaatatta gctaagtcat ataatttaag aactaatcaa
    25561 caagaacaaa cattagttga acatattaag gatttatttg aagtattaga atctatatta
    25621 gaactaaatc tatattcaga taaagatgta gagatactaa aaatatgttg tgctttgcac
    25681 gatttaggaa aaattaattc aattatgcaa caaaaaatgg agattaataa taaaatatcg
    25741 tatagttgct cagaagaaga gaggaaaaag ttagagtctg acaaaaaatc tttaaaaaag
    25801 atagcaagac acaatatatt ttctggagca tttttaaaag atatattaga aaaaatgaac
    25861 ttgttagaag aagataagtt atatatatat aaaagtataa tgttacatca tggaaactat
    25921 gaagattata tgaggttaag tactagtaaa gttcaagaag aaatttatga ttatattgaa
    25981 aaaggcattt tagaaaaaga agagtttaat ctgaaagata tagaaagtta tataaatgac
    26041 attttaaatg tagattttaa atttggtgaa gatgtattgg attatgatta catagataaa
    26101 ttaagtgaaa gtatgtttat agacagtgat tataacaatg gtcaaataga tgattcagtt
    26161 ttaaattata gaaagtttaa gtatatttta tataaaggga tgctgaactt aatagaccat
    26221 agtgcatcaa gtagacagaa aggtataaaa ttttataacg attttactga tgaagaaatt
    26281 gatgatatga ttttaaatga gatatataag agtcagggta atttagaaaa aaataatata
    26341 gagttcaata ctatacaaaa aaggttgaga gaactttctg gaagaaatgt tctgactgtt
    26401 gcatttacag gttcaggaaa aacagctgca gattatagaa agacttttaa aagaaaattc
    26461 tttttagtgc caaataaaat atcagcagaa agtttttata gaaaaaatat ttttcaaaat
    26521 aaaaatgatt tagatacaag aagtagtaat gattacattg gattacttca tggagatata
    26581 aacttatatt cagagaatga agataatgga gaacatgatt ttgtattgac attaagggat
    26641 atagatttga gtataaattt ttgtaaacct tgtgtaattg caacagttga ccagttatta
    26701 cttagtatgt ttaaatttcc gggatatgaa aaaatattcg cagccgtaaa aaatgcatct
    26761 ataactgttg atgaagtaca tttattggaa ccaaagatgt ttttgatttt gatatatttt
    26821 atgcagtttg catgcaagta cttagatgtt gattttcact taatgacagc tacacttcca
    26881 aaatcatata aagagcaaat gataaacaag ggaattattt ttcaagaaga aagtaatgaa
    26941 aatgttactg ataaaggaga aatagttttt attgagagca acaaggaaga agaaatttgt
    27001 gaaggtaaag atgtaaaggt ttcttttata aaggaaaaag aaatcaagtc aatagttgaa
    27061 ggtgctttag aaaataaaca aaaaattctt ataataaaga atactattga ttcagtcaat
    27121 agaacatatg agtttttaaa agaaaattta tctgataagt atggtggtgt agatatagat
    27181 gttttacata gtagatttaa gttcaaagat aaaaaagaga aatatagtaa aatattaaat
    27241 ggagagggtg atatttggat atcaactcaa tcagtagaaa tatccttgga tttggatttc
    27301 aatataataa taagtgattt agcaactatg gatagcttaa tacaaagaat gggtagatgc
    27361 aatagaaata ataaatatga atatggaaac ttttatattc tacctagtga agataaaatt
    27421 tatgataaca aacttaagaa cacaactaaa aacatcttaa aggacatatt aaaaactaac
    27481 tctattttta caatggggat tagaaaaact attttggatg attactatga taatagtgta
    27541 gttaaaaact attttgaaga gaattttata agttgtgata aagaaattaa gaatatttat
    27601 ggtataaata aagaaatttt tgatggattg gatttaattt ttaattttga accttacaaa
    27661 aatattgttg atagtaagaa ggaagcagct aaaattttta gagatgttga tgttagttac
    27721 aaaattattc tggaagaaga tttttataag gaagataggg agttacaaca agattcgatt
    27781 caagtatcag ggtttatatt taatagatta tattattatg gattaataag caaagtagaa
    27841 ggatacatgg tactaaaatc tagtagtaag tttgagtata atagtactgt aggcttaatt
    27901 ttgaagtgag catatgttta aatataatat acctttagac attgaaaata caaaaagtac
    27961 tactgtaagc ccactgtaaa aactattttt taaaaggaaa aataagttgt gagatagagt
    28021 gtctacaagt gtatatagat aataaatttg aggtttaaga ttaactaagt gggtttcagg
    28081 tacatcgcga aaataattat aagttggaga ttttgtatgt ttaagattaa ctaagtggat
    28141 ttcaaatatt gatatagtag atataataga agttttatta ttaggtttaa aattaactaa
    28201 tcggattttt aaatattctg actattatat aaggatatta ttagcttgaa tttaaaacca
    28261 ataatataaa acaacaaaat attatattta tgatataata aaagttatgg aaaaacagga
    28321 atattactat agagaagaga ggtaaactta tgaataattg gatagaagta actataaaaa
    28381 caacaacaga agcagttgaa cctataacga atatactata tgaacaagga gctggaggag
    28441 ctgtaataga agacccaaaa gactttttat tccaaaagaa aaatgaacta gactgggatt
    28501 atgttgaaga agaagtattt aaaaagaatg aagaagatga tgttcttata aaaacttatg
    28561 tttctgaaga aaaaaatgtg atggaatttg tcgaaataat aaagcaaaaa gttttaggat
    28621 taaaagattt tggtatagat ataggtgaag gaagtgtatc attggaccaa gtaaatgaag
    28681 ctgattgggc aaatgcatgg aaagcatact acaaaccaac aaaagtagga caaagggtag
    28741 tagtaaagcc tacatgggaa gattatgcta tgcaagatgg ggatttaatc atagagcttg
    28801 accctggaat ggcatttggt acagggacac atgaaactac tagtatgtgc attagagaat
    28861 tagaaaagta tgtgaataaa gattctaaag tatttgatat tggatgtggt agtggaatcc
    28921 ttgcaatagc agcagctaaa ttaggagcaa aagaagttgt agctgtagat ttagatgaag
    28981 tggctgtaaa agttgcaaaa gaaaatgttc ttgaaaataa agttgaaaaa agtgtatctg
    29041 taatgcatgg taatttaact gatgtaataa aagataaagc ggatgtaata gttgcaaata
    29101 taatagctga tataataaag atacttgcaa aagatgttca aaactttatg aaagaagatg
    29161 ctatatttat atcttcaggt ataattttgg ataaagtaga agaagttaaa gaaagcttaa
    29221 ttgaaaatgg atttgaaata gttgaagttc aaaaattagg tgaatggtca gcaatagttt
    29281 ctaagcttaa aaaataaggg atatggtgac gtataatgga tagatttttt gttgaaaaaa
    29341 ataatataaa tctacaagat aaaacttgca ctatagaagg tgaagatgta aaacatattt
    29401 caaaagtttt aagatgcaaa ctaggtgaga aacttgaaat atgtgacaag aataataatg
    29461 agtatatttg tgagataatg aatatagata agagtatagt taatttagag attttagaaa
    29521 aagttgatat aaatagagaa tcagaactta aagtaaggtt ataccaggga cttccaaaag
    29581 ctccaaaaat ggaaatgata cttcaaaaat taactgaagt gggtgtagaa gaaataatat
    29641 tagttcaaac taagagaagt gttgttaaag ttgatgacaa aaaagaagat aaaaaatttg
    29701 aacgttggga aagaataatt tatgaagcag caaagcaaag caaaagaggt aagataccaa
    29761 aattaagagg tgttttaagt tttaaagaag ctttagaaga tatgaaaaaa aataatgtaa
    29821 atatttgccc ttatgaaaat gaaagaacag tttcaataaa acatgcacta aaaaaatgtg
    29881 attctaatat agatagtgtt ggaattttta taggtccaga aggtggattt tctgaagaag
    29941 aaatagagca aatacaaaaa aataattgta atgttgtatc attggggcct agaatattaa
    30001 gaactgagac agcttctgtt gtagcatcaa caatagcttt gtatgaacta agtgatttag
    30061 gaggagaaaa ataaattgaa aaaagtagct ttttatacac ttgggtgtaa agttaatcaa
    30121 tatgaaacag aagctatgct agaactattt gagaaagatg gttatgaaca agtcaatagt
    30181 gaagagtatg ctgatgttta tgttataaat acatgtacag ttactcatat gagtgataga
    30241 aaatctcgtc aatatataag acgagttaaa aagaagaatc cagatgcaat aatagccgtt
    30301 gtaggatgtt attctcaggt atctccagaa gaaattttgg atatagaaga agtaaattta
    30361 gtcatgggta caaatgatag aagaaagatt gttgaagaaa ttaaaaagat aaattcaagt
    30421 aagaaagtta gtacagttga tgacataatg aaagttaaag cttttgaaga aatagaaatc
    30481 agccaaacta atggaaagac tagagcattt atgaaaatac aagatggatg tgacagattt
    30541 tgtacttatt gtatcattcc ttatgcccga ggacgcgtta gaagtagaga tattgatagt
    30601 atagtcgatg aagtgaaaaa attggctaat aatggctata aagaggttgt attaacagga
    30661 atacatgttg cctcttatgg aaaagattta aaggataggg atattaaact tcttgatgta
    30721 ataaaacaaa taaaccagat agaaaaaata gaaagaatta ggcttagttc tgttgaacca
    30781 attttattta cagatgaatt tgtaaatgaa gttttaaaga tggataaagt ttgtcctcat
    30841 taccatttat cacttcaaag tggatgtgat gaaactctaa aaagaatgaa tagacgatac
    30901 acaactttag agtacaaaac tattgtagat agattgagaa gtaaaatgcc agatgtggca
    30961 ataactacag atgtaatagt aggttttcct ggagagacaa atgaagagtt taaaaaaacg
    31021 tacgagtttt taaaagaaat agagctttca caaatgcata tttttaaata ttcaccaaga
    31081 aaaggaactc cagctgcaac tatggaaaat caagttgacc ctcaaatgaa acactttaga
    31141 agtgaacaac ttttaaattt aagtaaagta aattttaata aatttgcaac taaatttatc
    31201 ggccgtgagc tggatgtttt gtttgaacaa aatatagaag gcaataaata tgagggatta
    31261 acttcaaatt atataagagt tgttgttgaa agtgacaaaa atatacaagg tcagatatta
    31321 aaagtgaaaa taaatgatgt aaaagatgaa tatgtagaag gaattttgct ataacatgta
    31381 gaaattataa tatttataag ataggaggtg gaaagaatgg attgtatttt ttgtaaaata
    31441 gcgaacggag aaataccttc aactaaagtt tatgaagatg atagagtctt agcttttaat
    31501 gacttgaacc cagttgctcc atatcatata ttagttgtac ctaaaaaaca ttatgatagt
    31561 ttaattgata ttcctgataa agagatggac attgtgtcac atattcatgt tgttattaat
    31621 aaaatagcta aagagaaagg ttttgaccaa actggattca gagtcataaa taattgtgga
    31681 agtgatggag ggcaagaagt taaacatttg cactatcata ttttagctgg taaaaagctt
    31741 cctaattacg aagcgggaca aaactaaact aaattattga aaaattgagt tccttcttga
    31801 taaaaatact tgataaaagt aaaaatttag tttataataa acaaagtgtt aggttgtaat
    31861 gcatattatg caaaaagaac atagttacag tcccagcata attgcgctat tggagggagg
    31921 gaaaaagaaa tgtcagaagt aagagttaga gagaatgaaa cattagacag cgctttaaga
    31981 agattcaagc gtcaatgtgc aatgtctggc atcatgtcag aagtgagaaa aagagagcac
    32041 tatgataagc caagcgttaa gcgtaagaaa aaagctgaag cagcaagaag aaaaaacgct
    32101 aagaaatagt agtaaataag aataaagagg tgaaggggat gtcccttaag caaaagttac
    32161 aagaggattt gaaatcttcg atgaaaaaca aagatacagt gagaaaatct gtagtaactt
    32221 taataagagc ttctataaag cagtatgagg ttgataatag ggtcgagctt gatgaagatg
    32281 gaattatcga tgtaatagca aaacaattga agcaacgtag agatgcatta gttgaatttg
    32341 aaaaagctgg aagagaagac ttaataaaag aaacagaagg tgaaattgaa gttttaaaag
    32401 agtacctacc tcaacaatta agcgaagaag agttagaaga aattgtaaaa tctactatat
    32461 ccgaagtagg ggcaacttct atgaaggata tgggaaaaat aatgtcagtt atccaaccaa
    32521 aagttaaagg aagagctgac ggaaaactta taaataagtt ggtaaaacaa aacttacaat
    32581 agattgatat agcctagaga gaaatctcta ggctttttat agtttttggg aataacgagt
    32641 catatttgag catatctata atcaaagaaa attttgaaag aaggggaaaa atttgattat
    32701 atcagtaaaa gagattagga attttttgat aaacatattt ataccactaa taataggtta
    32761 cttaagtagc atcttaacaa tgattatcag tggaacagat atttcaacct attatttaca
    32821 actcacaaag ccaagctttg caccaccagc ttttatcttt cctatagttt ggactatatt
    32881 gtacatattg atgggtatat cttcatacct aatattaaga aagggttaca acttacctaa
    32941 ggtaagagat gcaatttttt attatggatt acaacttgta ttaaacttta tttggagtat
    33001 actatttttt ggatttggac ttagatttac agctttgata gatataataa taatgatttt
    33061 ggtttctata ataatgattt cgaagttttc taaaatagat aagagatctg gatacataaa
    33121 tttgatttat ttaatgtggc ttgtttatgc aggatttttg aactatttta tatggtttat
    33181 taataaatag aatgtaaaga ttttgtaaat taccctgtac ttttaataat atcataacaa
    33241 acgaaaaata aatagactat taaaaataat cattttcata tacaataata ttaatttaaa
    33301 tacaataaat ttataaaaat tgtatttaaa gattaacata ttaaagtatt agaattggaa
    33361 aggcttgaag ggagaggttt ttatgcaaat aatagtatct gggagacaaa tgaaattaac
    33421 tgacggaata aaaggatacg tagatggaaa attaagtagg ttagaaaaat accttgatcc
    33481 tgaatcagaa gtgaaagtaa cagtaagtgc gaaaaaggat agacaaaaag tggaggttac
    33541 aataattcct attaacggtc aaataataag agcagaagat gtagaagatg acttatatgc
    33601 agcaattgat attgtttgtg acaaattaag tagacaagtt gtcaaatata aaactaaagt
    33661 taaagacaaa gttcaaaata ataagagcat aagatttgaa aatcttgact ttatagataa
    33721 tagcagtgaa tttgatgatt atgattatga tgatgaagaa gatgaaaata tagtaataga
    33781 aagaagaaag aaatttaatg taaaacctat gagttctgag gaggcgatac ttcaaatgga
    33841 actagtagga cacaatttct atatgtttag aaaccaagat aattttgaaa taaacatagt
    33901 gtataagcgt aaagctggtg gatatggttt aatagaacaa gattaataaa aattgtatac
    33961 gtttagattt tatataagaa aaaataaaaa ggtaatcatg ttgatttttt atcaatatga
    34021 ttaccttttt attgtttaaa taatatatta gatattaggt atttattata taaaaatttt
    34081 aaaactaatc tgttacaaca tcaataaagt gcataaatac ctatttcaag cataaaatta
    34141 attaaggggg taatgcttat gttagaaata tccactgatt tacaagtaaa tcaaccagtt
    34201 attactgtta caagtaatac gtttattagt atagaaaatt atctatcaat attagaatat
    34261 gaagttgatt taataagaat aaagactaaa gttaaaacaa ttaaaatatc tggggataaa
    34321 ctttcactta agtatattac tgatagtgag ataggtataa aagggattat ctacaatgtt
    34381 gagtatgttg attaggagga gatacacttg ataagtttta taaggggata ctatgttata
    34441 gttgtggaag gagtaggact cgaacaattt ttaaatcatc ttataagaaa tgggataagt
    34501 gtttacaatg taactagaat aaaaaatact aaaatggagt ttcatataga tagacaagat
    34561 ataaaagaat ttaagaatgt ttatagagga agtaagtttg atataaaggt aaagcaaaaa
    34621 actggggtcc cttttattat caaaagagtt tataagcaca aaggtatgtg gatttgtgct
    34681 cttgtttctt tatttttatt gatgtctaca tcgcagtttg tgacagatgt atatatacaa
    34741 tctcctgaag gtataaaaaa agaagctctt agaaatgagc tttataaggt tggagtaaga
    34801 ccaggagtct ataagaagag tattgataga aaagaagtta gagaccatat gatgtcaaaa
    34861 tttaatgatg tggcatattt atctatcaat gtaaaaggaa caaatatatt tgttactgtt
    34921 acaaaaaagg cagaatccct aaaatctaca gaccaatcaa attattgtaa tgtaattgct
    34981 ttaaaaaatg gtataataga aaaggtaatc cctagaagtg gtaaatcagt tattaaatct
    35041 ggagacatag tccaaaaggg agatgtctta ttaaatggag ctaataccaa gtcaatacca
    35101 gaagtatggg caagtacttt ttatgagtcc acaaaaaagg caagttatgt agatactgta
    35161 aataaaaaaa ctggagaaaa gaaaaatata tatacactaa gtttttatga taaagagttt
    35221 acaatgagaa aaaatataaa atataaagat tatgttgttg aaaataaaga aaaaaaacta
    35281 tcaataggaa actatacttt tccaataaag ataaaaacga gtacttttta tgaaacaaaa
    35341 aaggttgaag taaaaaggaa taaagaagag ttaaaaaaag aattatctga aaaagcttta
    35401 aaagagttag aatacataat cccagcttcg gctagaataa tagatgtaaa acataacttt
    35461 aaggttaata aaaatatgtt agaatattta ataacagttc aaactagtga aaatattgct
    35521 aaaatttatc ctcttagtaa gtcagaagca gaaaggttta taaaggaaga aagtaaacca
    35581 gatgaaggtg aagaggaagt tccttccaat ccagaaaaaa gaccattaaa tgatataaga
    35641 aatgagtttg atgaggataa taaggataat aaagaccaaa acaattctga tgaaaataat
    35701 agtaatcaaa atagtaataa tagtcaaaat aataatagca ataacaacta ataaaattaa
    35761 acttaaaatc ttaggaggac taattcaatt gataatacaa aagaaattta caatagcaga
    35821 tggtaacttt gaaagagagt tatttggcaa ctttgatgaa aatgtaaaat taatagagaa
    35881 gactttaaat atagatgtaa tacttagaga aggcaatata attttaattg gagaagaaaa
    35941 aaatgtagat tctgcattaa aacttatgaa tgaattacac caaactgtat caaatggtaa
    36001 gcatttagat aagcagagta tttcttattc attatctctt ttgcttgaag gaagtgaaca
    36061 aaaaataaaa gaacttgagg ggacaatcgt cataactcaa aggggaaaag ctgttcaacc
    36121 taaaacttta ggtcaaaaag aatatataaa acttatagaa aataatgata taacttttgg
    36181 tgttggacct gctggaacag gaaagactta tcttgcggtt gctatggcag taaaagcttt
    36241 taaaagagat gaagttagta gaattatact tacaagacca gctgtggaag caggagagag
    36301 tctaggtttt ttaccaggag atttaaagga caaagttgac ccatatttaa gaccactata
    36361 tgatgcctta tttgaaatgt tgggtgctga taaatttaat aagtatttag aaagaggtac
    36421 tattgaggtt gcaccacttg catttatgag aggtagaaca cttgataatt catttataat
    36481 attggatgaa gctcaaaata ctacttctga acaaatgaaa atgtttttaa ctagacttgg
    36541 atttggctct aaagctgtag ttacaggaga tgtaactcaa acagatttac cacaaaataa
    36601 gaagagtggt ctaatacaag ctacagagat ccttaaaggt gttccaggta ttgggtctat
    36661 aatgctaaca gatagagatg ttgtaagaca tgagttggta cagagaataa taagagctta
    36721 tgagaagcac gacaaaagag aagaatttaa aaaagaagaa cgtaaaaaag tgaaaatgca
    36781 ggaaaagact ttcaaaagaa agtaaaagtg tagtaatata gatatatagc attattaatg
    36841 aataaaaagt aggtgtagtg aatggatttg atactagatg atagacaaga taaattagaa
    36901 gtaagtgagg agttaattga aaagataaag gatataatca tagaatgttt agattatgaa
    36961 ggatatgatg ataattatga agtgagtctt tcttttgtag ataataaaga gattcatgaa
    37021 ttaaatagag aatatagagg agttgataga gtgactgatg ttttatcatt tcctctttta
    37081 agtgatgatt ttgaggatgt tgagttagaa gaagaatccc taggtgacat agtagtatct
    37141 cttgaaagag ccttagaaca gagtatagag tataaccata gttttgaaag agaagtatgt
    37201 tttttaatat gtcatagtat gtttcatctt ttaggttatg accacgatac agatgaaaat
    37261 acaaaagaaa tgagagaaaa agaagaacac atattaaata agttaaacat aacaagggag
    37321 tagtttttat gaaaccagaa aaaactcgtc aaggtataat taaagcattt aatgcagcta
    37381 tagaagggat attgtataca tttaaatttg aaagaaatat gaaaatacat tatttaggtt
    37441 cagttgctgt tcttataata agtttgtttt ttaacttttc aaaattagaa atgataatgt
    37501 tacttatgtc catatgctta gttgtagttg ccgaaatgtt taatacagct atagaaaaag
    37561 ctgttgattt agtaactgat gaatatcatg ttcttgctaa gatagcaaaa gatgttgcag
    37621 ctggaggcgt tctagtggca gcactaaatt cagtagtagt tggatatatt ttgttttatg
    37681 ataaattgac agatatatct ggaatattaa tttataaaat aagagaatca gaattacata
    37741 taaccttgat atgtatatta ttggttctta tagctgttgt agttgtaaaa gcattgactt
    37801 ctacaggtac tcctctaaaa ggaggaatgc caagtggtca tgctgcctta gcatttgcta
    37861 tagcaactgc aattacactt atgactgaaa gagttgttgc ctctactctt gcatatataa
    37921 tggctgtatt agttgcccaa agtagaattg aaggaaaaat acataccttt tgggagacta
    37981 ttgctggagc tttattaggt gtgttgatag ctatattagt atttcagctt ggaatgttct
    38041 ataattaaaa taaatgtaca taaaatattt aaaataaaac aaatctgtgc taattaaatt
    38101 tttatgatat aatgtagagt attaaataaa aataactttt aattattgta tacaggagga
    38161 gttgttgtgg ataacataga attgttaagg ttggcagaag atgccagaca acattcttat
    38221 gctccttact caggttttag agtaggtgca gctcttttaa ctaagagtgg taaagtttat
    38281 actggatgta atatagaatg tgcatcatta ggtggaacaa attgtgcaga aagaacagct
    38341 atttttaaag caatatcaga gggtgataag gatatctata aaatagctat agcaagtgat
    38401 aactcagaaa ataatgagca aacatatcca tgtggaatat gcaggcaggt aattatagag
    38461 tttggttctg atataaaaat aataacggga tatactaaag gagaggtgtt tgagcatagt
    38521 ataaaggatt tgttgccaaa ctatttctct ggaaatgatt taaaataaat ttaaaagtat
    38581 aaataaattt aagtaattaa aacaagaaga taaaaagtta ggagacagtt aatgttcaaa
    38641 tcaggttttg tcagtatagt gggtagacca aatgtaggaa aatctacttt aatgaataat
    38701 gtagttggag aaaaaatagc tataatgagt gataagcctc aaactacaag aaatacaata
    38761 caagcagtat atacagatga agaaatgcag atagtattct tagatacacc cggtattcac
    38821 aaaccaaaaa ataaattagg tgaatttatg gtaaaggcag caacagaagc ttttaaaaat
    38881 gtagatttaa tattatttgt agttgatgat tctaaaaaaa taggtcctgg agatagaaag
    38941 ataatagagg atttaagaag tgttaagaca ccaataattt tagttgtaaa caaaatagac
    39001 caactagacc aaaaagatga gctatttgat ataatcaaaa tgtatgatag agaaggtatt
    39061 tttaaagaaa tagtaccaat atcagcatta aaaggaaaga atacggatac cttaataaaa
    39121 gttatacaaa attatttaga agaagggcca aagtattttc cagattatat gattacagac
    39181 cagccagaaa gagtattaat agcagaactt ataagagaaa aagttcttca ctatcttaat
    39241 gatgaaatac ctcatggtgt agctgttgaa attgaaaaaa tgaaagcgag aaatgataag
    39301 gaaatagtag atgtatctgc tgtaatatac tgtgaaagag attcacataa gggaataata
    39361 ataggaaaaa atggtaggaa actaaaagga ataggtaagt cagcaagaca agatatagaa
    39421 ttgcttttag gttcacaaat aaatcttcaa ttatgggtta aagtcaaaga aaattggaga
    39481 aatttacaaa attatataaa taattttgga tataatgata aataaaggtg ggttatatgg
    39541 ataggaaact ggatgcttcc caagatttat tatatgaagt aaaatcatta attgataata
    39601 ataaagtatt ggagttaaga gaattaatag aggaatatca tataattgat atattcgata
    39661 taatggaaaa tttagaggaa gacatgaaaa ttcaattatt tgaagtactt cctttagata
    39721 tggcatcttc tatattagaa gaaggtagtg tagagttttt tattagtatt ttatctaaac
    39781 tggatgtaga acactcgaaa aatatacttg aacttatgtc tcttggagat atggcagaca
    39841 agttgagtga acttgaagaa gaagaaagag aacacataat aaatcttttg aatcaagaga
    39901 atgccgatta tgtaaaagag ttactattct atgatgaaga ttctgctggt ggaacaatga
    39961 ccactggata tatttctata aataaagata tgacagctct tgaggctata gaccatatga
    40021 gagaagaagc tgaagaagct gaaactattt attatatata tgtggttgat gatgaagaaa
    40081 aactagttgg agtattgtca ttaagagaat taataatagc tagagacgca aatatagtag
    40141 aagatttgat gagtgaaaat ataatctctg tttatgtaga tgaagataga gaagaagcag
    40201 taagattagt atctaaatac aatttaatag caattccagt agtagacaga caagaaaaat
    40261 taaaaggaat aataacagta gatgatataa ttgatgtaat ggaagaagaa gcaactgaag
    40321 atatgtataa atttgcagga agttcagaac atgaaagaga agttgctgaa aaagaaaacc
    40381 ctacattgag agagcaaata atatcagcac ttagaggacg attaccttgg ttaattatta
    40441 ccttggttgg agggttgttg gcttcgttaa tactttctaa cttagactat ataatgaatc
    40501 ctgtatatgc tccattagta ttttttatac ctgtagtaat tggtatgggt ggaaatattg
    40561 gaactcaatc atcatctgtt acagtaataa cattatctaa taaggattta aattttagca
    40621 atgtggttag agaaggtatt gtaggtatta ttacaggtct tttgtgtagt ataataacag
    40681 gtattgtaat ttactttgtt atgagaaagt tagacattgt attaattgtt tcaatatcat
    40741 tatttataaa tatggtttta ggtgcaacaa taggtgcgtt tatgcctgtt ttattaaaaa
    40801 aaatggatgc agacccatct acagtttcat caccaattat atctacagct cttgatataa
    40861 ctggtatagc agtttacttt ataataacaa cggcattatt gtcaaaaatt gtttaataac
    40921 tttatgtatg atttatcctc ttcttactaa aaatataagt ataaatgtaa gaagggggtt
    40981 ttttaaaaat gaacaatatc agttgggaag tttttaaaaa aacaggtagt atagatgcat
    41041 atttatattt ctgtgattgc aaaaacatac atgaagaaat tgaagaagta agggagaaaa
    41101 aagaagacga tgataatcct gaacacccag gggatagtac ttaaagctat aaggtataag
    41161 gaaagtgaca taatacttac actatttaca agaaagcttg gaaaagtatc tgcaatagca
    41221 aaaggagcta aaaaaaataa gagctctttg ctttcatcat cacaattatt ttcttatagc
    41281 aattttacct taaaaaaaca aggtaatatg tacaaggtta ctcaaagtga aataataaaa
    41341 agtttttata atatatccta tgatatagag gcattttctt atgctacata tattacaaaa
    41401 ttagttgaaa attctatact tgaaaatcag actaataata ggctatttat attacttgcg
    41461 cagactctgt atttgtatac acaggataat acagacaata ggtttataac agcagcattc
    41521 gagttaaaat ttttagacta tataggattt aaacctatag taaataaatg cattaattgt
    41581 gaatgtaaaa ttttacaaaa ttctgtgttt aatatctacg aaggtggtat actatgtagt
    41641 aagtgtagta aactttttga taataatata aaattagact taacaactat aagtcttatg
    41701 gaatatgtat taagaaatga tattttaaca tgtagtaaag ctaaagtatc aaaatatata
    41761 acacatgaac ttgagaatat tctagacaag tatttgaaag tttatgttga taatattaat
    41821 tttaaatcat tacacgtatt gcaaagtgta aaaaataata agggagtgga taatgatgag
    41881 tagtaatata actattgaaa tggttgattc agtctttgaa agagttccag gagcaactta
    41941 tgcagaagca aaagaagcat tagtaatgtg caatggagat gtaattgagg cagtaatata
    42001 tttagaaaat aaaaaaaata cttgtaattg taaagcaaaa tctgctaaag aaactatgga
    42061 agaagtattt ggcaaagatg gagaaaatat aaagtttcaa ttaaaagagc ttcttagaaa
    42121 aagtagtgta gtgagaataa tagttgaaaa agatggaaaa actatgatga acattccttt
    42181 aacagttgga gttgttggat tagcttttgt accattagct actttagttg gattatcagc
    42241 tgctgttata agtaaatatc gtataaaagt tcaaaatgaa gaagatggag aaattgtaga
    42301 tttaggtgaa ttgaatgaag aaaaacttca cgttttgaag aatatgataa ctaatgcagc
    42361 aaaagatgtg aaggatgtag tagttgacaa aaaagaagat gacaaagatg taactgctga
    42421 ccttatgaaa gaagaatctg aaaagaataa agaagacgaa gacgaaaata aatagatata
    42481 aagtgacttt taaaaaatga agagaagata attataagaa ttatcactaa cattgacaaa
    42541 ttttatagaa tttgatattc taaaagttgt agaagaacta ttaaaatagc ctttcgtgta
    42601 gacgagaggc tttattgtta taggagggat ttttatgaat tttcaagaga tgatactggc
    42661 gttgcaaaaa tactggtcaa agcaaggttg tatcatgatg caaccttatg atattgaaaa
    42721 aggtgcagga actatgaatc ctaatacttt tttaagatca ttaggacctg agccttggca
    42781 agtatgctat gtagagcctt caagaagacc agcagatgga agatatggtg aaaacccaaa
    42841 cagactatat caacatcatc aattccaagt tatactaaaa ccttctccag ataatataca
    42901 agaattatat ttggaaagtt taaaagagat tggaattgac ccaagtgagc atgacataag
    42961 atttgttgaa gataactggg aagctgctac agttggtgct tggggacttg gatgggaagt
    43021 ttggctagat ggtatggaaa taactcaatt tacgtatttt caacaagtag gtaatattga
    43081 atgtgagctt gagacaggag aaattacata tggattagaa agattagcta tgtacattca
    43141 agaagttgat agtgtttatg atttaaaatg gaatgataaa ataacttatg gtgaagtatt
    43201 taataaagct gagtatgaaa actcaatgta cgcatttgaa ttatgtgatg cagatatgtt
    43261 gtttaatctg tttgatatat atgaaaaaga agcattaaga cttatggaaa atggccttgt
    43321 aataccttca tatgactatg tgttaaaatg ctctcatgca tttaatacat tggacgcaag
    43381 aggtgcaata ggagttagtc aaagagcttc atttataggt agagttagaa atatggcaaa
    43441 gactgttgca gaaacttttg taaaacaaag agaagaaatg ggattccctc ttttaaagga
    43501 cggtgacaaa taatgaaaaa ttatctttta tttgaaatcg gtgttgaaga aatgccatca
    43561 agatttgtag gcagtacact agaacaatta aaaaacaatc ttagtaaatt atttgatgaa
    43621 aatagaatag cttttgataa aataaatgcg tatgggacac caagaagact tactttagta
    43681 gtcgaaggat tgagtgatag acaaagtgat ttagaagagg aaataaaggg tcctgctaag
    43741 aaaattgctg ttgatgcaga aaataattta acaaaaccag cattaggatt tataaaaagc
    43801 aaaggattaa gcgaatctga catatatttt aaacaagttg gaaaagaaga atatatattt
    43861 gcgactataa agcaagatgg aaaagaaact tcagaagtac taaaagacat attaccagag
    43921 actataaaat ctgtagtatt cccaaaagct atgcgttggg gaggaaaaaa tcttaaattt
    43981 gcaagaccta taagatggat agttgcattg ttaaatgata aagtattaga gtttgattta
    44041 gaaggaataa tatcttctaa tgtaacaaaa ggtcatagat ttttaggtga aagtacaata
    44101 gaagttgatt ctatagaaga ttattttgaa aaattagaaa aaaattatat agttttagac
    44161 caaaacaaga gaaaagaaat gataagaaaa caatgtatag aagtagcaaa ttctttaggt
    44221 ggagaagttg aatttgatga agatttactt gaagaggtaa cttatttagt tgaatatcca
    44281 actgcttttt atggagaatt tgatgtggat tatataaaac taccaaaaga agttgttata
    44341 actcctatga aacaacatca aagatatttt ccagtactta aagaaggaaa actgttacct
    44401 aactttatag ctgttagaaa tggtgattct tacagaatag acaatgttaa agctggaaat
    44461 gaaaaagttt tagaagcaag acttgcagat gctttatttt tctatagaga agatactaag
    44521 agaaacttag aaagctacat agaaaaatta aaaactgttg tattccaagt aaaactagga
    44581 actatttacg acaaaacttt aagacttgaa aaattaagtg ctgatatact tgatagttta
    44641 ggtttagtag atgaaaaggc agatactata agggctgcta aattatctaa ggcagattta
    44701 gttactggaa tggtaggaga atttgatgaa ttacaaggtt ttatgggaaa agaatacgca
    44761 aaagttggag gagagaatga tgttgtaagt gaagctattt ttgaacatta tcttccaaga
    44821 tttgcaggag atatacttcc taagactaat gcaggggttg ccttatcaat agctgataag
    44881 ttggattcaa tagcaggttt ctttgctata ggaatacaac caacaggttc tcaagaccca
    44941 tatgctttaa gaagacaagc tttaggtata cttagtatac ttatggacag aaaagttgct
    45001 gtggatataa aagtacttat tgaacatgct ttagataatt attctgaatt agattttaat
    45061 aaagaagaag ttgttgagca aataatgaat ttcttcaatg agagagtaaa aaatctattt
    45121 aaagatttag gaataagata tgatgttgtt gatgctgttt taagttctga tataaatgat
    45181 gtttctgata tgcatatgag agctttagag cttaataatt ggctagaaaa agatgaatta
    45241 gtggagatgc ttactgcatt taatagagtt tctactctag ctcaaaaagc agaaagtgat
    45301 aaaattgatg aatctttatt aaaagaagat gctgaaatta gactttacaa tgaatttaaa
    45361 caagtaaagg taaaagttaa tgaattatta aaggataaga aatatggtat tgctttagat
    45421 gaatttgcat ctttaagacc agtagttgat aatttatttg atacagttat ggttatggat
    45481 aatgatgaag ctattaagaa caatagactt gctttactta aacaagtata tgatactatg
    45541 ctagaaattt gtgatttatc taaaattgtt tataaataaa atttaaacta tttataagaa
    45601 ataaggctgt ctcaaaatag agatagtctt atttttcatt gttgagatga tgaaaatata
    45661 tttgatttca tagaaaaaga gtgtctcata aactaaaaag ttcattttga gacacccatg
    45721 ctttttgtaa gtaaatataa taaattatat tttatactta tcagttattt tgtttaaaat
    45781 attatcattt gaatttaccc attcataaaa attgcctgat gatgcgtccg atattttata
    45841 aagcatttca ggaatatcac tagctttaaa atctccaagt gattttccca atctagtctt
    45901 acctatttca aaactgcctc caacaaataa ttcaaatgca tctgtagata taccatcaac
    45961 attcttcttt ttaccacata aacctatgct accaacttga tgaacaccac atgaatttaa
    46021 acatcctgat atatataact taggtgcttt atttaaaatt tcttcattat tttgtaatct
    46081 aaaataatct atgatttcat gtaacatttt ctgactattt tgtatgccca tttgacaaat
    46141 tggaacacct atgcaagata tactttgttc taattgagaa ttacaactaa tagttttact
    46201 tatttctaat attctttttg cttcatttcc atttaaattt aaaatatata atccctctgt
    46261 cattcctagt ctaatcatag gattttcaac attatctaat tctttaagta aagtacttaa
    46321 atcctttgtt aacaaaatac ctccaactgg atgtatatat acagtgtata aaccatcctg
    46381 tttttgaggt attagtctag aatcttgtat atctatttta actccaggtt tagagtaatc
    46441 tatttcttca atattgagtt caagactacc attttctttt tctaatttat agtattcttt
    46501 aaatttttct aagaatagtt cttcaccaag tgattcgacc atatatctaa ccctagctct
    46561 gtttttattt tcataatttc cataatccat aaagaattta atcatacctt caacacaata
    46621 taaggcgtct ttcggcttta taagttcatc aagttctaaa gcaactttgg gttgtttacc
    46681 tagacctcca cctaagaaaa ctctgaaata tggttcatca tttttcaaag tagcaacaaa
    46741 tcctaagtct tgtatactac aatgagcagt atctgtgtaa caattagaat aagaaacttt
    46801 taattttcta ggtaaatggt atgtagtagc atttttgata aaatatttat cagtagcaac
    46861 tgcatatgga gtaacatcaa agacttcact agggtcaact ccagataatg gagataatcc
    46921 gacatttcta ggataattac caccaccacc tctagtgaat atatcatttt ttattccttc
    46981 ttccatgata tcaacaattg aatttataga taaatcgtgt aattgtatag cttgtctagt
    47041 tgttaagtgt atcttatcta agttgtgttt aatagctatt tcatagattt tattaagttg
    47101 atactgagat aaaactccag cagatactct aagtcttatc ataaaagatt ttttgtctct
    47161 ttgagcataa acaccatatc caccagaaaa tcccttatat tgcattttat ttatttctcc
    47221 atttaaaaat tttgaagaat attctttaaa attaggtagt tcatttaaca atatcttttt
    47281 aaaattatcc attatttcac ctcattgtta gtcttgtata aaaatatatc tattgtataa
    47341 tagatatata tattattatc tagtcaggat aaaaatataa cagaataatt ctattaaaag
    47401 taagaataat aaggacatag tgagtatttt gtttttattt tacaaattaa gtataatatt
    47461 tttgttttat aaaatataat taagataaat agataatttt gtaattttaa tatataatat
    47521 ttagtagagt gtgggagtag cacttaatat ttgcaggagg agtttttgta tatgggagaa
    47581 ataataaatg cattagatag agccctagac ataattttgc tgttatatca tgaaaagaga
    47641 gaaatgggaa taactgaaat aagtaaggct atgggagtat ataaaagtac tgtacataga
    47701 actttggtta ctcttgaaaa caaaggtttt gttatacaaa atgcagagaa tggtaagtat
    47761 tggctaggaa taaatttata tgcaataggt atggttgtgg gagaaaaaat gtcattgact
    47821 gaaatagtaa aaccatatac gaaaaaatta aatcaagaat ttaacgaagt agttaatgta
    47881 tctatattag aagaaagagc tcaagattct ccaagaagta tcataataca taaagagtat
    47941 ggttcaaatc aattactttc agtaaatcca tccgttggtt caagtagtga atgttattgt
    48001 tcagcagttg gtaaatgtct tatggcattt aatgattcta tagattttga aaaatataga
    48061 aaaacaccaa tacacaagta tacagaacat acaattgata attgggatga tatgatgctt
    48121 tttttagcaa aaataaaaga acaaggatat gctatagatg atgaagaact agaacatgga
    48181 ctaacttgta ttggagcacc tatcttagat aaaaataata aagctattgc agccataagt
    48241 ttgtcaggtc caactataag aatgagagaa ggggactttg agtataagat taaaagagtt
    48301 atagaaactg caaaaagtat atctgaactt tttagatgat ttttaatctc gataataaaa
    48361 ataggctata tttaaattgt tatttgtaaa tatcagttta aatgtagcct atttttcttt
    48421 aatctaaaat taaatattct taaaatttaa aatgttattg aaatatataa gcgaatgtgt
    48481 tatcttttaa ttaagcaata aaaatagaac aaggttctat actatagaac aaaattgatg
    48541 catatatagt atttatacaa aatataaata ttatatattt aaaattaagt aaaaatatta
    48601 cataaagggg agatttgaga aatggaaaaa gtcaagttga gtgttgaaag atgtaaggga
    48661 tgctatcttt gtattgaagc ttgcaaaaaa gatgcaataa gtctttctga ctacacaaat
    48721 aaaaaaggct ttgtaactat taaagtcgat gaagaaaaat gtattcaatg tggcgcttgt
    48781 tatacaatgt gccctgattt agtatttgag atattataaa ttatttttat tagaggggag
    48841 aaaaggtatg caaagtttat taattaaagg aaatgaagct ttagcagaag gtgctatacg
    48901 tggtggctgc agattttatg caggttatcc aataacacca caatcagaaa tattagaaat
    48961 gatggcatgg agacaaaaag aagttggagg agtatttatc caaggtgaat cagaaatagc
    49021 cagtgtaaat atggttatgg gagcaagtgc acttggagca agagctatga cttcttcatc
    49081 tggtccagga ttttcattaa aacaagaagg tattgcatat tgggtatcag ctggtttgcc
    49141 agcagttgta gcatgtgtgc aaagatatgg tataggtgat ggatttatag gagctggtca
    49201 agataattat tggcaagcag taaaaggcgg tggaaatgga gattatcatt taatcgtgtt
    49261 agcgcctaac agtgttcaag aaaatatgga tatggcatat gaatcttttg aattggctga
    49321 aaaatatatg catccagtac ttatactttc tgatgctaca ataggtcaaa tggtagaacc
    49381 ttgtatagca ccaccaatga aagaatacga tatggataaa gctccatggg ctgcaaaagg
    49441 aacacctgta ggagaaaaaa ataaagtaat aactgatata acatattttg aagaccaaga
    49501 tacatggcaa aaagggtata tagaaaaaat gagaaaagtt caagaagatg aacaaagatg
    49561 ggaagagata gaaatagaag atgctgaagt ggtatttgtg gcatacggta tttcatcaag
    49621 aatagcagaa ggtgcagtta gagatgctag agcaaaagga atgaaattag gtctaataag
    49681 accaaaaaca ttgtggcctt acccaagaaa agcatttaag aaattaagtg attcattgaa
    49741 gggacttgta acagttgaaa tgaacatgat ggcacagatg aaggaagatg taattatagc
    49801 atgtgataat agatttccag tatattcagt agcaacagct caatatatgg cagaagtaaa
    49861 tcaattaata gattttgctc aacagattat agatggaaaa gctaagcaag aggaggtatt
    49921 ttaattatgg ctaagaaagc accagcaata atgatgtgtg aaaatatgtt ttgtggaggc
    49981 tgtggacact ctatagtcga tagaattatt ggagaagtat taacagaaat ggatatatgt
    50041 caagatacaa ttatatgttc agatataggt tgtaatcata tgtttcaatt tagtatgaat
    50101 gtagatgttg tcgttccacc tcatggtaaa atgggtgcag caatggcagc tatgaaaaga
    50161 gttagaccag ataaatatat atttacaata gctggagatg gtggagctta tgcgataggg
    50221 cttggggaaa ctatgtcagc tgctactaga aatgataatg ttatattcct tgttatgaac
    50281 aataatatgt ttgcaatgac aggagggcaa atggctccaa ctactataga aggtcaatat
    50341 acagcttcta ctccagcggg tagaaattac gcagatcatg gttcaacatt tgatgttgta
    50401 aaagttatgg gaaatttaga tatagcatat ctagcaagag gaacaataac taaccctaaa
    50461 gaaataaata caacaaaaag atacatcaaa aaagctctag aaaaacaaaa agaaaagaaa
    50521 ggtttttgct taatagaagt gcttgtacca tgtccaacaa actggggatt aaagccagta
    50581 gatgctatga agagaattga aaatgaactt gttccaaagt atccacttgg agaatttatt
    50641 gattagggag gaaataatat gttgaatgaa attatatgtg ctggttttgg aggacaggga
    50701 gttcttacag caggaaaaat tataatgtat gttgcatata aggcagaaaa gaaaattaca
    50761 tggttcccat cttatggaaa tgagatgagg ggaggaagtg caaattgcaa tgttgttgta
    50821 agtgatgaaa aaattgcaaa tccttgtgta aaaaatccag atatactatt gggaatgaac
    50881 agcgtatcag tagataagta tgaaagttta atgaaaaaaa atggttatat gtttgtcaat
    50941 gaatcactag taagtaagga tagaaagtac agagaagaca ttaatgttat aaaagtacct
    51001 gttactgaaa tagcacaaaa tttaggcaat gaaaaagctg ctaacatttg catgttaggt
    51061 gctatggtaa agagtttgga tttatttaca aaagaagaat ttgaaagtgg tatgtgtgaa
    51121 tactttgaaa atcaaggcaa aggtaaattc aattctaaaa atgtagaagc atttgaagca
    51181 ggatacgact acgaatgaat attttaaata tttaaaataa ttattgaaat acttattttt
    51241 atatgttagt atttaattaa taaaatatag aacgtcgttc tggacaatag gacgaagtct
    51301 ttaggccgga atacaagaac gacgttctgt atagtagaac tagggggtgt taaattgaaa
    51361 gttttagtaa taaatcctgg tggtacatcc acaaaaattt ctgttttcca agatgaaaat
    51421 gaaattttga aaaaaaatat aacccataca agagaagatt taaaaaattt ttctaaagta
    51481 tttgatgaat atgattatag aaaacaactg atagtagata ttttaagtag tgagaatcat
    51541 agtataaatt cttttgacgc agtagttggt cgtggtggac ttatgaaggc tataaaaggt
    51601 ggtacctata ctgtgagtga agaaatgatt gaggatatga gaaatgaaat aaatggggaa
    51661 catgcatcaa atttaggtgc attattagct aaaactatag ctgatgaaat aggagtacaa
    51721 tcatttgtag tagacccagt ttctgtagat gaatttgatg atgtatcgag gattacagga
    51781 atatcagaca tagaaaaagc aagttggtta catgcattaa accataaagc tgtttcaaga
    51841 aaaattgcac aaaaactagg gggaaaatac gaggattata actttattgt agctcattta
    51901 ggttcaggaa tatcgattgt agcacataaa caaggcaaaa tgattgatgg aagtggtggt
    51961 aggtctgatg gtccattttc tccagaaagg agtggtggat tacttgcata tcctcttata
    52021 gaattgtgtt actccggaaa atatactcat gatgaaatgg tcgcaaaagt aagttcgatt
    52081 gggggaatgt acgattattt aggaacaaag gacatgatag aaattgaaaa cagaatcaag
    52141 gagggtgatg aaaaggcaaa acttataatg gatgcattta tttatcaagt agcaaaagaa
    52201 atttctatgt atggagcttc actttcaggg aatgtagata gagttatctt gacaggaggg
    52261 atatctcact cagaaatggt agtcaaagga gtagcagaaa aagtttcata tctagctcca
    52321 atagagatag taccaggaga gatggaaatg gaggcacttg ctctaggagc acttagagta
    52381 cttaatggag aagaaatagc aaaaacttat taatatttag gagaaagagt atgttaaaag
    52441 attttaataa tttattagaa gaggctaaaa agcttgaacc tgttattgta agtgttgctg
    52501 ttgcagaaga caaagaagta ttaaaggctg tgaaatcagc aacagattta aacattataa
    52561 agccaattct tgtaggagac aaggataaaa tagaaagtat atcaagagaa attggattaa
    52621 aaggtcatga aataataggt tgtcaaaatc ccgatgaatc agttaaaaaa gctgtagaga
    52681 tagttaaaaa taaggaagct aaagttctta tgaagggatt agtaaataca agtgtctata
    52741 tgagagctat attaaataaa gaaacgggtc ttagaacagg aagattatta agtttgcttg
    52801 cagtatatga attacctcaa tatcataaac ttctttattg tactgatagt ggaataaatg
    52861 tatcgccaaa cttaaatcaa aaaaaagata taatgacaaa tgcacttctt actatgaaaa
    52921 gtataggcat ggaaaatcct aaaactgcga tacttactgc aaatgaaatg gtagacccta
    52981 agatacaatc tacagtggat gccaacctac ttgtagagat ggaaaaatcg ggagaaatac
    53041 caaagtgtat agtggaaggt ccaatagcat ttgatgtagc atttgatgca catgcagcag
    53101 aacataaagg tattaaaagt aatattgctg gtgatgttga tttattagta tttccaaata
    53161 tagaagcagg gaatatatta ggaaagtcat ggcttagatt taataaagct aagtgggcag
    53221 gtatagtttt aggagcaaca aatccgataa ttttaggttc acgttctgac acagctgaaa
    53281 taaaaataaa ttcaatagca ttagcgtgcc tagcatcaca ataagaaatt attattaagg
    53341 aggagaaagt attatgaaat atgcaaaaag aatggatatg gtaaaagctt cagctataag
    53401 agcttctcaa aagaaaatag ctcagaaggt ggcaagtggt ggaactgtta tatcttttgc
    53461 tgcagggctt cctgacccaa atttatttcc aatagaagag ataagtgaaa taactcaaaa
    53521 agtacttaat gaaaggggaa aatttgccct agcatatgga cctactaaag gtgaagatga
    53581 gttgttagat ctattagtaa aaagaatgaa agaagaagaa aatattgata caaaagcaga
    53641 aaatattata ataactactg ggtcacaaca agggatagca ttaagtgcta tgattttact
    53701 agaaaaagga gatatagtag ttacagaaaa tccaagttac ttaggtgcaa taaatgcatt
    53761 tagaccttat gaatgtgatt ttttaggagt agatactgat gatgaaggaa tggtaacaga
    53821 tgatttagat aaattattat ctgaaaattc taacataaag gtaatctatg taataccaac
    53881 atttcaaaat cctacaggaa aaacatggtc tttacaaaga agaaaagatt ttatggaagt
    53941 cgtgaataag tatgatgtca tagtaataga agataatcct tatggagaaa taagatttac
    54001 accagagcct ctacctacac ttaaatctct tgatactaaa gataaagtat tatacttagg
    54061 ttcattttca aaagtattat gtccagggtt tagagttgct tggatgtgtg gtaatgtaga
    54121 catcatagat aaggcagaac ttttaaaaca aggtatagat ttacagtcaa atcaattttc
    54181 gcaagtacaa gtaatagaat ttttaaagaa atacaactta aatgaacata tagaaaaaat
    54241 aagagcagag tataagaaaa gatgtctgct aatgttagat gctatgaaga aacatttccc
    54301 agaggaagct aaatatacag aaccagatgg aggaatgttt atatgggttg aacttcctga
    54361 aagtataaat gtagatgatt tattggataa agccattgat gctggagttg cttatgtttc
    54421 tggagagtcc ttctttgcaa ataatggtcc aaaaaatact atgagactta actatacaac
    54481 aatgtcagaa gaacaaatcg ttaaaggtgt tgagatactt gcagaagtta taaaaaaaga
    54541 actcaattat gcttgtgaat aaatataaaa agtgagggtt taaatatggg agaaaaagaa
    54601 aacggtataa agtttggaaa gttaatgttt caacttgtta ttatagcaat atcttgggaa
    54661 ttagtttata ttataccatt tatccaatat acattatatg atccaatcct aaaagcatta
    54721 gaatgtacaa acactcaact aggttttcta cttacaattt atgggttagg taatatattt
    54781 ggagctccta taggaggctg gttagcagat agatttgatt atagaaagat aattttaggt
    54841 tctgtatttc ttaatggagt agtatcattt ttatttgcat ttaatatgaa ctatccattt
    54901 gcagttgcta cttgggtagg ttgtgcaatc acatcattag ttatgaacta tccttctatg
    54961 gtaaaaatac ttagagttat aggaaaagat aatcaaggta aagtttatgg attcaatgaa
    55021 gctatggttg gagtttctgg cgtagtaatg ggagcaatat tcttatatat ttatacatgc
    55081 ttttcaactc ctgtattggg tatgagatgg gtaatgatat ctttaggaat attatcaata
    55141 gtgatgtgtc cagtattatg gtttgtaatt aaagatgtag atatcagaga agacaaagaa
    55201 gaagaagcaa gtgaaaaaat gtctgctggc gattttatga cagtactaaa atcaccaaac
    55261 acttggctag taggaataag catattctgt gtatattcat tcacagttac aatgtcttat
    55321 tttacaccat atataacatc agtacttgga ggttctgtgg cattgtctgg ggcattagca
    55381 ataataagac aacatggtct aaaattgttt ggagcaccat ttggaggata ttgtgcagat
    55441 aaagtaaaat cacctacaaa agtactacta ccaatatatg tatttggtat agcagtaata
    55501 attttattcc tagtactacc tgcatctact ccaatgacta tctttatagc tttaacattt
    55561 gtagtaggta tattaggtta catgggaaaa ggtatatact atgcagttca agatgaagta
    55621 aaagttccag ttaaatattc agcaactact ataggtatag ctgcagcttt aggattttca
    55681 ccagatgtat tccaatttgc attaatagga cactggatag atacttatgg caataaaggt
    55741 tacacatata catttatatt ccagatagca attctaataa ttggtatact atcttgttta
    55801 tatatattaa aagttaagaa gaaaagagaa agtaagttag aagcataaat attgtaaaaa
    55861 taccaaatta ttaagtttta tagcaatact taaaatttaa agtgcaacac accaaaatgt
    55921 tatcaagttt tctaggtttt agtataaagt tacccctaaa ggtctggaat tgagtagcaa
    55981 ttatcatcta tttatatatt tacataaacc tatttaattt aaattaaaag aatttcaaaa
    56041 ataggtggta attgtactca attttacacc tcataataaa tacgaaaatt taaaatctaa
    56101 ctatatacta ttcaattata tattaataat tgtatatggt actatttata tagtaacagt
    56161 ttcaggcttt tcattacatg tattccaatt tatattgttt gattatttgt caaatacata
    56221 tcgttaaaaa gtttataaat ttacgtttat atatcgatta atattctttg ttttagagat
    56281 agatacttat agcttgtgga ttaaaaataa tataaataga agatagattt tttagatata
    56341 ttgagttgaa gattatatag aatgttgaaa catagctatt taaattattg tctataaata
    56401 taaaatgaat ggtggtgagt taagtgaccg atttagttaa caccattaat ggaattgttt
    56461 ggtcacctgt attagttgca atgtgtttgt gtataggatt atatttttca atgaaattaa
    56521 gattttttca aataaaagat gtaaaagaaa tgtttactct tttgcttgaa ggagatagct
    56581 ctcatgttgg aatatcttcg ttccaaggtt ttgctacatc tatggcagga aggataggaa
    56641 ctggaaatat agctggtgta gctgtagcga tagcaatggg agggccagga gcattagtgt
    56701 ggatgtgcat aatggctaca ttagggtcgg caactgcatt tgtagaatct actttagctc
    56761 agatatataa agatgagcat gatggacagt acaggggagg tcctccatat tactttgaaa
    56821 aaggtcttgg ttggaaaaaa tgttcaattt tattttcagt ggttgcaatc ataagttata
    56881 cattttttat gcctggcaca caatcaaata ctctatatct agcaatgaat caagcatttg
    56941 gattttcaaa aatgacaata gcagttacat cttctattgc actaggtata ataatttttg
    57001 gaggaattaa aagaattggt ttatttgctg agaaagtagt acctataatg ggtggagcat
    57061 accttattat gacattggta ataatcatag caaatataaa tctagttcca ggagctatta
    57121 tgacaatgtt taaatctgca tttggatttg gttcggtttt tggagggatg ttaggttcag
    57181 caatatcttg gggagtaaaa agaggtatat actcaaatga agcgggagaa ggttctggaa
    57241 cttatggtgc agcagcagca gaagtgagtc acccagccaa acaaggatta gtccaagctt
    57301 tttctgttta tgtagacaca ctattaatat gtatggctac aggtattatg attataataa
    57361 caggaatgta taatgttaca gatgtttaca caacattacc aggtgtagaa ccaggtccac
    57421 aatatgtaca gagtgcaata aatacattac atcctcaatt aggtgatatt tttatagcaa
    57481 tagttttact actatttaca tttacaacat tattagcctt ctcatacatg atggagacca
    57541 acgtatctta cttagtgact agaattaagg cagaaaaaca tgaaaagcac ataattaatg
    57601 tctgtagatt tatgcttata atatgtgcag caatgtgttg ctttatagaa ccacttacaa
    57661 gttgggcact tggtgatata tgtataggtg tattaacata tataaactta gttggtatat
    57721 ttacactaaa aaaaccagct ataaaagcat attacgatta tcaaaggcag aaaaagatgg
    57781 gagtaaaaag gagcgataga acttttaatc ctatagaatt agatataaga aatgctgagt
    57841 tttgggaaaa tagatactta aaagaggata agcatgagtt aaattaaagt tataataaaa
    57901 tataaaaatt actaaataaa tttagtggga ggtaagattg gtatgaaaga aagaataata
    57961 caagtggctg attcaaagaa agaaaaaatt ctagggctat gtcaatcttt atatgatgaa
    58021 ccagaaattg ctttgcaaga atataaatct gctaaaaaaa tatcagaatt tctaagagaa
    58081 gagggttttg atgttgagga aaacttggca ggtatggcta cagcttttaa agcaaccaag
    58141 aaaaatggag atggtcctaa aatagcattt atagcagaat atgatgctct tccaggcaat
    58201 ggacatgcat gtggacatca tttaattgca tctatgggag ttggagctgg aatagctctt
    58261 tcaagtatac tggatactta caagggagaa gtaagtataa ttggaacacc tgctgaagaa
    58321 actggagatg gaaagcctta cttgatagaa catggtgtat ttgatggcta tgatgcagca
    58381 atgatgatac atccaaattc aaaaacttgt gtaacacctg aaattatagc aataggaggt
    58441 ctagatttca tatttactgg aaaagcatct catgcaggag ctaagccata taacggaata
    58501 aatgctttag atgcagtagt actactatat aataatataa atgcactaag acaacaatta
    58561 gtagatggaa cgagaataca tggtattata ctagaagcag gaactgctgc aaatgtaata
    58621 cctgatatgg gaaaagtaag attagagata agggcaaaag aacaaaatta ctttgatgaa
    58681 gtagtagaaa aagtgaaaaa ttgtgctaga ggtgctgcaa tagccactgg atgtgaactt
    58741 gaattttatc actttgaacc aacttgccaa ggattaaatg aaaataaagt tttggtagac
    58801 atatttacaa agattatgga ggaatttgga atatatgaag atgaacaagt aatgttaggt
    58861 tcaacagata tgggaaattt aagtcaaata atgccatgta tacatccttt gatgaagttt
    58921 tctgaaaatg gagaagaact acatacaaaa gaatttttgg aggcttctat aaattcatat
    58981 gcaaaagata gagtaattga tggtataaaa atattagctt taacaggatt taatttattt
    59041 gaaaatccag agttattgaa aaaaatgaag gaagagtaga acttagacta tttttaatta
    59101 tactctttaa aataagaaga gtgtctcaaa atgaactttt tagtttatga gacactcttt
    59161 tttgcatgaa attaaatata tttttattat tttaacaatg aaaaagaggc ttatctgttt
    59221 ttatataacc ttttttaact tgtagcacaa aatatcatga atgattacaa ttcgaatgat
    59281 aaaatcgatt ataagatata taggaggggt acatatggaa actttagaag taagaaatat
    59341 tgaattgagt ggtacaaatt atgagatagg atacagacta ggagaattgg ttgctaatat
    59401 gccagagata atagaaggtc agattaataa atctaatctg gtaagcaaaa aagaagaaaa
    59461 agagatgata gagttgtttg ataaatattg tccaggtctt aatgaagaat tgcaaggttt
    59521 tgctgatgca attcaagtga attgtaatca aattttatat tatactatga cttatcttaa
    59581 accaggttgt agtcaagttg cattaacacc agaattaact gaaaatgggc atgtactatt
    59641 tgcacgtaat ttcgatttct cacacaatat ggaggatttt gttttatgta aaactaaagt
    59701 aaatggaaaa tatgcacata taggtactac cgttatgcaa tttggaagag gtgaaggtat
    59761 gaatgaatgt ggattaggtg taagtcagtc atcatgtggt attcctgtag gcaattcaga
    59821 tggtttgaga aaaccagcaa ttgtaggttt acagttttgg gctgttatta gatatttgtt
    59881 agaaaattgc aaagatgtag atgaagcatt agaatattta aaagatatgc caattgcata
    59941 caatattaat ttattgcttg cagataagtc tggaaacatt gcacttgtgg agactttaga
    60001 tgggaaaaaa gaagtaaata taatcaacag tttagaaagt aagagagaat attttttaca
    60061 ctctactaat catacacata ttgataaact tcataaatta gaaccacaat caatgaaaaa
    60121 ttctattcat agatataaat taattaaaga atatataaat aaggctaaaa aaattggaga
    60181 gaaagagtta atgaatttat tgtctttaaa gtatccaaat ggcttatctt gtaattacta
    60241 taatgatttt tttggaactt taaaaagtat agttatggat ttaaatatag gaaagtttaa
    60301 tattttatgg ggtggactag agaataaatg ggagagctac tatttaaaaa atgacattaa
    60361 atctataaca cagaggataa acataaatat tgaaaaagca ccatctgact tttttgattt
    60421 cattgaataa aaaatgtatt taattattct aaataattag gctatataaa tcaactaaaa
    60481 gtttttattt atcgtattga attagttata atattttagt atagtaaaaa atagtgctat
    60541 tttacatatt taaagagttt aagtagaaga gaggtgccat attggattac ttaaagtatt
    60601 ttgaaaaagc tgtaatgtat attgagaata atttacatga aaatataact gtaaatgatg
    60661 tggcaaaaga aactggatat tcttattatc atttaacacg cttatttaag tctatgtttg
    60721 gtgagagtgt aggaagttat ataaaaaaaa gacgattagt aagtagtaca aaagaacttt
    60781 tatatagtga taaaaaagtg atagatatag ctattggtag tggatttgaa tcttcggaag
    60841 catttagcag agcatttaaa tctatataca aggttagccc tatagaatat agaaaaaata
    60901 gaattgatgt atttgttggt aaaaagaaaa aattagagtt agattttatg agacatcttg
    60961 ttggaaatat aacgattaaa ccagttataa aagaaataga aaaaataaag gtaataggta
    61021 taaaggataa agtaatttta gaaaataatt cattacctga cttgtgggag aaattcagaa
    61081 aagtacatca tattgtccca aatactttgc catcaaagag agtttttgga atctgtgaag
    61141 caatctctga aatacaccta gttagtgaaa gtatggaatt taatgagata ataggacttg
    61201 aagttaatag ttatgatgtg attccaaatt catttgtttc aaaaactatt aaggaaggaa
    61261 agtatgctat atttactcat actggtagct tagataactt agacaaaact tatgaatata
    61321 tatggggtac ttggttttta agttcaaaag aagaactgga tataagagat gattttgaag
    61381 tatatgatga acgattttta ggtcctagta atgtgaactc acaaattgat atttatatac
    61441 ctataaaata atctataaga aaactaaaag ataatttgat taagaaatag atgttcgtaa
    61501 aagagcatct attttttatt tttatcagat ttagataatt ttaataataa aagaaataaa
    61561 aataagttct taaatttcta agaagaattt agaatatagt cgaaataaga attgtatatt
    61621 tctgaaaatt ctaattagta caattttttc ctttataaaa ttgaaaaaag atgtatttat
    61681 ttatcaaaaa tattatatta aaatgatatt aataaaaaaa catttacaat attagcatat
    61741 agtacagaaa aaagatgtaa tttgtaaaat ttatgttaag cagtaaaatt aaaaatttaa
    61801 agatattata gggaggttat aattttatgg aaaacgttat tacaggtcta agtaaaggtg
    61861 cagagtggtt tatcggtttg tttcagaaag ggggagaaca atttataggt cttgtttcag
    61921 gtactcttcc aacgctaatt gtattaatgg tagctattaa ctctttgatt aagataattg
    61981 gtgaggaaag agttaataat tgggcttcta agctaggaaa gaactctttt acaagatata
    62041 ttctacttcc attagtatca gtatttttct tgggaaatcc tatgtgctat acatttggta
    62101 gatttttaaa agaagagcac aaagcaggat tttatgatgc agcagtttca tttgtacatc
    62161 caattacagg tctttttcca catgcaaatg caggagaact ttttgtatgg ttgggaatat
    62221 cagcaggttt gactacttta ggtaaagaaa ctactacact ggcattgtgg tattttatag
    62281 ttggtctaat tgtaattttt ataagaggta tagtaacaga aaaaatgtat gcttttctaa
    62341 caagaaaaaa tagagcaaca aataaggctt aggaggtaga taaaatggag gagaataaaa
    62401 tattaaaaat agaaaaggga acttcaggct ggggaggtcc tttgtatata aaaaaagaag
    62461 ggaatagaaa taagatacta tcaatgactg ctggtggtat ccatgaagta acattaaaaa
    62521 taaaagaact actgggttgt gaaattgtag atggatttaa aactggagtt tctgatgaag
    62581 aagtagcagt agttattatt gattgtggtg gaactgctag atgtggagtt tatccaaaga
    62641 aaaaaatacc tacaataaat gtaaatccag ttggaaaaac aggtccttta gcaaaattta
    62701 taacagaaga atattatgta tcagatgtta atcctaactg tataagtgtt gtagatgggg
    62761 aagatatgcc acaaaaatct caagaaaata aaagcgaaaa taagagttct attagaaagc
    62821 ctgataatta tgatgaggtt aagtcaaaag cacaaggtga atatgctaaa aagaacataa
    62881 tactttctat tggtcaaggg gcagggcaag tagtatcaaa attttatgat gcaggtcgag
    62941 acactatcca aatggtaatg aataacgtaa taccatttat ggcatttgta agtatgctta
    63001 tgggaattat tttagcatct ggactgggag actggattgc aagagttata tctccacttg
    63061 caggtaatat tggtggatta ttgattatat cagtaatttg cacacttcca ttcttatcac
    63121 caatactagg acctggtgca gttatagctc aagtagtagg gactcttgta ggtacacaaa
    63181 ttggtcttgg tgcaatacca gcatatttag cacttccagc tttatttgca ataaatgggc
    63241 aagctggatg tgattttgta ccagtaggat taagtttggg agaagcagaa ccagaaactg
    63301 tagagtatgg tgttccagct ttattttact ctcgtttaat aactggtcca atagctgtta
    63361 ttattgcata tggagttgca gtatttgcat tgagataata tttaatgtca atataaggct
    63421 tggaattaat taataaaatt gtaaatataa atttaagcta gtcaagattt tttgttaatg
    63481 aaagactagc ttttatacta ttaattagct gtaattatcg agttagatta atactaaatt
    63541 ttcctttatt aaagtgaaat tttatgtatt aatttggttt caaatttgta ctagaatgaa
    63601 atcaaggagg agatacaaaa tgagtgtaac tgagaaaatt ccttctattg accgcaagat
    63661 atttaagata ttgattatgt gtagtaaaaa agagtttgtg agtattaatt caatagcaaa
    63721 tgaattgaat gtcacaacta gaagtgtaag gacgtatata aaacaattga ataaagattt
    63781 aggtaatgat atagcagtaa tcaaatatat aaagggtcaa ggctataaac tagaaataaa
    63841 agatgagcag atactcaata agattattga tatgaataga aaaaatgtat tttcattaaa
    63901 ttcaaaagaa gatagagtag agtttatact aaattacttg atagaactag atggatttat
    63961 tacacttgat agtttagctg atgagatgtg tgtaggaaga actactttag taaatgattt
    64021 ccagtatgta gaaaaagttt tggcttcata taatttaaac ttgattaaaa aacagaatac
    64081 aggtatgaaa ttaaatggaa atgaacttga tattagactg tttatattaa atcagttgta
    64141 taaaaactca aggaaagatt tcagtaattc aaagtatttt aaaggaatca aaaaagaaga
    64201 aatcataaat ttagaagaaa aactattgac tttatttaaa gaaaataatt tttatgttac
    64261 agatgaaatg ttaagagaag ttattaacta catagtagtt ttagtctata gagtaaaaga
    64321 agaaaagaaa gtaaaagact atgatgtaaa gtttgattta cttaaatcat atgatgaata
    64381 ctttattgct agggaaataa aacatataat atcaggaatg tttgaatgta ctttaaatga
    64441 tgaagaaatt atttatttaa ctataccatt agttagtgga aatgcaccag catcagaatg
    64501 tgctttaaat agtagtagaa ttagtaaaaa cattgatgag ttgatggaaa atatatttaa
    64561 tcaaatatat gtcgatatgg gtatttttat aaatgaggat gaattaagag taggtctagg
    64621 atatcatctt agttttactt taaacaggct attatttaat ataaagttaa aaaatgtttt
    64681 gttagaagag attaagcaaa attatatact tccatttaaa ttagcacaaa tagcaggaaa
    64741 agtaatagag aaaaagtata acttagaagt ttcagaagat gagattggat atatagcaat
    64801 ccatttcagt ggatatttag aaagaaatag cagtagattc tattcaataa aaaaaatagc
    64861 aattatatgt agtacaggtc taggaacagc aaaactattg aaaataagag tagaaaaact
    64921 gataggaaat aatcctaaaa ttgatactct ttcaagtttt aatttgagaa atattaactt
    64981 agatgaatac gatatagttt ttacaactat tgatttagac acatcgaata taaatacaat
    65041 agtattaaaa ataaatacaa tatttgatga aaacaaatta agagaacaat taaaaacagt
    65101 attgtgccta agagaaggga atattgacac tactaattct acaaatttac taataaataa
    65161 tttgttagat gaagataaat ttatgatatt aaatgaaaag actatacttg cttcattaga
    65221 aaaaatgatg gaccatctta tggatttggg atgtattgat gataagttta gaaaaaatat
    65281 agtcaataga gaagaaaaat ctcccacagt atttgataaa ggtttattat ttcctcactc
    65341 tgtaaatgaa aaatcagata agtttttaat ggcagttgga attttagaag aaccaataga
    65401 atatgcaaat agaagtataa aaataattct tatgacaatg tttccatgtg agaataagat
    65461 agactcagac ttattagtaa aaatttatga agaagtttta aagataggcc aagatgtaaa
    65521 attaacgaat aagataagta aatgtagaac ttttttagaa tttaaaaagg tgttacttaa
    65581 aaaccttata taactattgt acagcattta tagttgttat acagatttaa aaataatgtg
    65641 atttttggaa ggtgtataaa tatgaaatta ttagtaattt tatttgttgc ttatatttta
    65701 aatactatat ttataatgaa gcagaataaa ttgtatttta aaactttaaa tagagctaaa
    65761 aaaaagggtg atatagtgtc tacaggcaaa aagaaaagct atttttctaa aggaagtata
    65821 gccattatat cttcagattc agatgggttt ataaagtttg gagaaatttt aaaagggcgt
    65881 acagtaatgg ctaaatttaa agagattgaa gaaatagaag gattagatat atatagtgca
    65941 gagcaaaaat ttaaagatga agagagtatt gtacaagcta taaaatttat aaaagaaaaa
    66001 ataaatgttt cttttaatta actcaatata aatataaatt atcaggagga atgtcatgaa
    66061 atatgaagtt aagataagtg ggataggcag tttagttaaa gagttaatgg atgaaagcaa
    66121 ttgtcttatt atatatgatg aaaccattaa tgatgacgac ttaaaggata tatctgtaat
    66181 tcattcgata gcaacattaa aaagtgatgt tgaaatagga gatacactta ctatagggaa
    66241 tagagattat tgtatagttt cagttggtga tattgctcag aagactctta gagaaattgg
    66301 gcattgtaca atcaaatttg atggaaaatg tgaagtaaat ttaccaggag aaatacatgt
    66361 ggaaatagga aatccagata taactattgg agatttaata actatttctt aatttgaaaa
    66421 taaaattatt ataacaggag gaattggtat gttagattta aacagaaaac ttgcaaaatt
    66481 ggaagaggaa ggtaaaaaaa taaaagtagc tcttatagga gctgggcata tgggaaatgg
    66541 aatggtaagc caaatggcaa atatgaaagg tattgaagct tctattgttg tagatataaa
    66601 tttggagttg gctcataaag cttttactga tgcaggaata gatgaagaaa ttatagataa
    66661 tgtaacaaat gaaaaggatg cagaaataaa attacaagaa ggaaaagtat tgacatgtaa
    66721 tgactttctt gtggcttgta aaactaagtc aatagatgta gttatagatg caactggggg
    66781 tattgcaatt ggtgcagaga tagcattaaa ctctatttta aataaaaaac atatagttat
    66841 gttaaatgct gaaactgatt gtgttgttgg accaatactt aaaaaattag cagatgatgc
    66901 tggagtgata tttacaggtt ctgcaggaga tgagccaggt gcagtaatgg aattatttga
    66961 ttttgcagat gcaatggggt ttgaagttag agtgataggt aaaggtaaaa ataataaatt
    67021 agatttagat tgtaatcctg atacagttag agaagaagca gaaagaaaag gagcttcacc
    67081 tcatatgata gcttctttta aagaaggaac taaaacaatg gtagaaatgg ctttaatgtg
    67141 taatgcaact ggatttgtgc ctgatgtaag aggtggtcat ggtattgaag ctacagttaa
    67201 tgaagtacct aagaaatatg cattaaaaag cgaaggtgga gtattagata attatggtgt
    67261 agttgatttt gtaaatggta tagcacctgg agttttcgta gtagtagccc ataaattaaa
    67321 agcagttaat gatgaactaa aatatttaag tatgggtgat ggacctaatt acatattata
    67381 tagaccatat catttatgta gtttagagac tcctttatca gcagctatgg cagtcttaga
    67441 ccataaggct acaatagtac ctaaagctgg actagtagca gaagttatga ctatagctaa
    67501 gaaagatttg aaaaaaggtg agtttatgga tggttatgga gcatatacat gctatggtac
    67561 tatagaaaaa tacgatgtag caaaggctat gaatgctgta cctattggtt tgataagtaa
    67621 aaagactaaa gttgtaaaag atattaaaaa aggtgaagtt ataacttacg atatggtaga
    67681 gatagaaaaa gatactactt tatatcattt aagacaattg caagaaaaaa tatttgggta
    67741 agatttgatg gtaatataaa tagatattag taaaaagggt tgatggttat ttttaaatca
    67801 acccttttaa atttttatat attcttgtta ggatactttc tttaaaagta tattataggt
    67861 tatttgtagt cgtaaaaatt attttgaatt agttctgcaa ttttatattc acattgaaac
    67921 aatattatta aaaattttaa tataaaatga attaaaatga ccaattatgt attataatat
    67981 taactgtaat actaatatag ttctattaat taaagaaata tcccccatta atatataata
    68041 aatatcttta agcgagagaa cttagtaaaa aatatatcgt attcaataaa aaatctgttt
    68101 acagaatggt atatatagtt atataatata ctatataaga tgcgaaaaga taaaaagtat
    68161 agcacaatga aagaaggtga ttattattca gcttaatgaa agacaactaa aaattataga
    68221 tatagttaag gaaaatgaac caataacgag tgaaagtatt gcctccagct tgaatgtgac
    68281 tcgtgctaca cttagatctg atttagctat attaacaatg acaggaatat tagacgcaag
    68341 accaaaagtt ggatattttt attcaggagt tagtgaaata aatttaattg gtaaaagtgt
    68401 aaaagaaaaa acagtagagg atataatgag catgcctgta ctagctaaga aggatgaaag
    68461 tatatatgat gtaatagtca ctatgttttt atctgatgta gggagtatag ttattataga
    68521 tgagaatgaa gagttatgtg gagttgtttc cagaaaagac ttgctaaaag caactatagg
    68581 aggttctgat ataaataaaa tgccaatagg tatgataatg acaagaactc caaatgtagt
    68641 cactttaact aaaggagcaa gtgttttatt agcttcaaga aaaataatag aacatgaagt
    68701 agattcgatt ccgattgttg aatataaggg agaagacaaa aatcatatga gagttgttgg
    68761 gagaatatca aaaaccaaca taactaagct attcttagaa atagttgaca attaaggagg
    68821 tatgctggtg aaaaacctaa ttatatatgc agtatcagat tcagtagggg agactgcaca
    68881 acaagttgca aaggcatgta tgtctcagtt ttatgtgaat gaaacttatg aaataaaaag
    68941 atttccatac atgattaata aaggagtact acttgaaact ttggagaatg caaaagctga
    69001 aaacgcttta attgtatata cattagttga tgaagaatta tgcagtattg ttgaaagata
    69061 ttgcgaaaga gaaggtctta gttgtataga tttaatgaca gatatactaa gagaaataag
    69121 caagagaaca ggaagaaaac ctaaaagaga agctggtata attagaaaat tagatgaatc
    69181 ttactttaag agagttgaag ctatagaatt tgcagtgaaa tatgatgatg gaaaagaccc
    69241 tagaggtgtt cttcaagcag acataatttt agtgggaata tcaagaacat ctaaaactcc
    69301 tttgagtatg tatttagcta ataaaaatat aaaagtagct aatgttccat tagttccaga
    69361 aataccaatt cctaaagaag tgtttgagat agatactaaa aagataatag gtcttactaa
    69421 ttcacctgaa aagctgaatg agataagaac ccaaagatta aaagctttag gattgtccag
    69481 taaagcaaac tacgctaatt tagaaagaat acttcaggag ttagattatt cagaagagat
    69541 aatgaaaaga attggatgcc cagtaataaa cgtttcaaat aaggcaatag aagaaacagc
    69601 aggtataatt ttagacataa tgaaagaaaa tggtctaaag atatacaaag aaatagaaat
    69661 ttaataatgt ctattaataa aaatgatata aattaaaata aaaagattaa tgggggattt
    69721 aacaatggaa actaagtatg tttatagttt tggtgaagga agcaaagaca tgaaatcttt
    69781 actaggaggt aaaggtgcca atttagcaga aatgactaag ataggcttac ctgtccctcc
    69841 tggattcact ataacaacag aagcatgtaa tgattattat gttaacaatg aaagtataag
    69901 agcagagata ataaaagaaa tagaagagca tttagctact ttagaaaaag acttaaataa
    69961 aacattagga tgcaataaga atccattatt agtatcagtt cgttctggtg cagtattctc
    70021 tatgccagga atgatggata caattcttaa cctaggtctt aatgacaata gtgttgttgg
    70081 cttagcagag gctacacaaa atgaaagatt tgcatatgat agttacagaa gattcataca
    70141 aatgttttct gatgttgcta tggaagttcc aaaatataaa tttgaaaatg tattagacag
    70201 agtaaaagaa gcaaagggat acacagttga tacagaactt acaactgatg atttaaaaga
    70261 aatagtaaaa gaatttaaag caatttataa aaaagaaata aaaaatgatt tcccacaaga
    70321 cccaaaagag caattaatgc ttgcaataga ggctgtattt agatcatgga ataatcctcg
    70381 tgcaatcgta taccgtaaat tgaatgatat agctcataac ttaggaacag cagtaaatat
    70441 tcaatcaatg gtatttggta atatgggaga aactagtggt acaggtgttg catttactag
    70501 aaatccagct acaggagaaa ataaattatt tggtgaattt ttaatgaatg cacaaggtga
    70561 agacgttgtt gcaggtataa gaactcctca aaatatatca actcttgcag atgtaatgcc
    70621 agctgtattc gatgaatttg taaaaattac tcatatactt gaaggtcatt ataaagatat
    70681 gcaagatata gagtttacta tagaaaatga aagattatat atactacaaa ctagaaatgg
    70741 taagagaaca gcagcagcag caataaatgt agcggttgat ttagttgaag ctggaataat
    70801 tgatgaaaaa gaagctatca tgagaattga gcctaatcaa ttagaccaat tattacatcc
    70861 aaaatttgaa gataaggcat taaaagaagc caaggttata gcaaaaggtt taccagcatc
    70921 accaggtgca gcaagtggta aagtttattt caatgctgat gatgtagtaa aagcaaatga
    70981 aaaaggagaa aaagtagttt tagttagatt agagacatct ccagaagata tagaaggaat
    71041 ggttaaagca gaaggaatcc ttacagctag aggtggaatg acatcacatg cagcagttgt
    71101 tgctagaggt atgggtaaat gttgtgttgc tggatgtgga gaaataaaag ttgatgagtt
    71161 taataaagaa ataagagcac ttgatgatgt agttataaaa gaaggtgaat acatttctat
    71221 agatggttct acaggaaatg tgtacctagg agatgttaag aaaacagaag tatctttaac
    71281 tggaaacttt gaaaaattaa tgaactgggt agacaaacac aaatgtatga tggttagaac
    71341 taatgcagat aatcctagag atgctcgtgc agctatagag tttggtgcag aaggtatagg
    71401 tctatgtaga actgagcata tgttctttga tgaagctaga ttgccagcag ttagagaaat
    71461 gatattatct aatacagtag aacaaagaga aaaagctctt gaaaaaatat taccaatgca
    71521 aagagaagat tttgtagagt tatttaaagt tatggatgga aaaccagtta atataagatt
    71581 actagaccca ccactacatg aatttttgcc tcatgatgat gagactatag aagaactttc
    71641 aaaatctatg ggaataaaag taagtgatat taagaagaga atagttgatt tagatgagtt
    71701 taacccaatg cttggacaca gaggttgtag acttgcaata acttatcctg aaatatgtgt
    71761 aatgcaatct aaagctataa tacaaggtgc tatagaagca atcaaagcag gtgttaaagt
    71821 ttctccagag ataatggttc cattagttgg agaagtaaat gagttaaaaa taataagaaa
    71881 aatgatagta gaaactgttg acgctataat aaaagaagaa ggtatagaag ttccttatac
    71941 tgtaggtact atgatagaaa tacctagagc ttgtttaact gctgatgaaa tagcacaaga
    72001 agcagacttc ttcagttttg gtactaatga cttaactcaa atggcatttg gatattcaag
    72061 agatgatgct ggtaaattct taggtcaata tgtagatgaa gaaatattag aaaaagaccc
    72121 attccaagta ctagaccaaa atggtgttgg taagttagtt aagatgggag ctaaattagg
    72181 tagagaagtt aaaccagaat taaaactagg aatatgtgga gagcatggag gagaaccatc
    72241 ttcagtagag ttctgttata gtgtaggact taactatgta tcttgttcac catttagagt
    72301 gccaattgct agacttgcag cagctcaagc atctataaaa aatcctagat aataatagac
    72361 tgcaaaatat gtaactaaat aaaaataaaa tcccctattg ttcaatgtat caaattaagt
    72421 atttgtaaat tgaatatagg ggatttttat tataaaaatt taacttatac agttgtaagt
    72481 gaaacgtatt taattatatt gcatatatta ttgtagagag aaatttcaac tatcaattaa
    72541 attgagttta ctggagggga taaagttgac aaagtgtcct aaatgtggaa aggaagtatc
    72601 atcacgtcca ggtagtatat gcccacgatg tggatttaaa gtagcagatg agagtctaaa
    72661 aataagatgt ccagaaccta gttgtagggc tttggtatct aggaaactgg attattgtcc
    72721 taaatgtgga tgcaaactta gaggatataa tatttctgaa tttgttaaca tggtaagatg
    72781 taaaatagat gagacatttg ataaaaaata attaaattta gagttaagct tttgagggtg
    72841 tctcaaaatg aactttttag ttcagaaggc actctttttg tatggaatca aatatatttt
    72901 tataatttaa acaataaaaa agaggcttat ctctatttta gtataatccc cttatagtag
    72961 acatttaaat aaaaggctat tataataagt ctaaaaagcg tatactctaa gggggttttt
    73021 ctatgtctaa aaaacataaa aaatatagca aagaacttaa actaaaagct gtaaatttat
    73081 atataaaaga aggatactca tcatacaaaa ttgctgagat gctgaatata agaagcaaaa
    73141 cacaagttca aaactggata aaagattata aaaataaagg taaaactgca tttaatgagg
    73201 aaactagagg cagatttaaa aatattagtc tagaaaatga taatagaaaa tttaaatctg
    73261 ttgaagaaga attgaagtac ttacgcatgg agaatgaatt tttaaaaaag ttaagtaccc
    73321 tattggacaa gtcaaagtaa gcgataaatt taaaacaatt aaacttatgt ctaggaagta
    73381 tagtatttct agtatgtgta agttgatagg tgtgtcaaga agcggttact ataaatggct
    73441 aagttattct aaaaaatctt ccgatagggg tatcaaagat agaattatta aggattatat
    73501 aattgaaata cataaaaaat atagaggaac ttacggtaga aaaagaattt gtacttattt
    73561 aaataaaata cttgatagcc ctattaatca taagaaagta tataggttga tgaaagaact
    73621 aggaattaaa tctattatta gaaagaaagt atatagacgt aagtttaaat catatgaggt
    73681 atatgataat atattaaatc gtgaatttag agctaatcaa ccattagaaa aaatttgtat
    73741 ggatataaca tacataccta tcggtaaaaa attcttatac atgaatgtag ccaaagattt
    73801 atttaatggt gaaatagtgg catatgagat aagtacaaaa atggatacta aattagttaa
    73861 taaaacagta aatcaactaa taaatatgaa tttagctaaa gattgtattt tacatacaga
    73921 tcaaggttca caatatacaa gtagatctta ctctaaaagg cttaaagata atggtattat
    73981 acaatctatg tcccgaaggg gcaactgctg ggataatgct cctatagaaa gttttttcag
    74041 tcattttaaa tctgaattaa tatatttaat tgatactaca gatccaaagg aaatgattag
    74101 tctaataaat gattatattt atttttataa taatgaaaga atacaattaa aaaacggaat
    74161 gagttcgatt gaatatcgaa ct
//
LOCUS       DAEQJM010000015        73928 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.015, whole genome shotgun sequence.
ACCESSION   DAEQJM010000015 DAEQJM010000000
VERSION     DAEQJM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 73928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73928
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.015"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(391..2670)
                     /locus_tag="KRQ43_001266"
     CDS             complement(391..2670)
                     /locus_tag="KRQ43_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH2741630.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITEKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYIARSNGNIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFAQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2941..4395)
                     /locus_tag="KRQ43_001267"
     CDS             complement(2941..4395)
                     /locus_tag="KRQ43_001267"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBH2741631.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYNSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4559..5428
                     /locus_tag="KRQ43_001268"
     CDS             4559..5428
                     /locus_tag="KRQ43_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH2741632.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDATSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGYLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5642..7714)
                     /locus_tag="KRQ43_001269"
     CDS             complement(5642..7714)
                     /locus_tag="KRQ43_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH2741633.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLSHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYASIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKLLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSKKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNCLSTISPVVFTNLEQNQKLSIKKGITTAKEENRVSIL
                     RYDIEKIG"
     gene            complement(8017..8859)
                     /locus_tag="KRQ43_001270"
     CDS             complement(8017..8859)
                     /locus_tag="KRQ43_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH2741634.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEISTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(9106..9600)
                     /locus_tag="KRQ43_001271"
     CDS             complement(9106..9600)
                     /locus_tag="KRQ43_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH2741635.1"
                     /translation="MSTLVTLLGLLVCTKISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKLSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPRMPLSVSLALAAVISSTDLVAVKSITQGLNFPKNMMSILEGESLLNDDDRII
                     NIME"
     gene            complement(9752..10723)
                     /locus_tag="KRQ43_001272"
     CDS             complement(9752..10723)
                     /locus_tag="KRQ43_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBH2741636.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPDEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTRALMSAVPVQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(10724..11701)
                     /locus_tag="KRQ43_001273"
     CDS             complement(10724..11701)
                     /locus_tag="KRQ43_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741637.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMVIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPVLGKNKDKRLYSIPGQV
                     PNPIGIPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            11920..13479
                     /locus_tag="KRQ43_001274"
     CDS             11920..13479
                     /locus_tag="KRQ43_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2741638.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKRKEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            13585..14544
                     /locus_tag="KRQ43_001275"
     CDS             13585..14544
                     /locus_tag="KRQ43_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741639.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            14547..15359
                     /locus_tag="KRQ43_001276"
     CDS             14547..15359
                     /locus_tag="KRQ43_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741640.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVISLTIISKKFSSNT"
     gene            complement(15574..16476)
                     /locus_tag="KRQ43_001277"
     CDS             complement(15574..16476)
                     /locus_tag="KRQ43_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH2741641.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            16831..18009
                     /locus_tag="KRQ43_001278"
     CDS             16831..18009
                     /locus_tag="KRQ43_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH2741642.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINSGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            18018..18674
                     /locus_tag="KRQ43_001279"
     CDS             18018..18674
                     /locus_tag="KRQ43_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HBH2741643.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            18674..19339
                     /locus_tag="KRQ43_001280"
     CDS             18674..19339
                     /locus_tag="KRQ43_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HBH2741644.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     ILGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            19444..20220
                     /locus_tag="KRQ43_001281"
     CDS             19444..20220
                     /locus_tag="KRQ43_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH2741645.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            20282..21616
                     /locus_tag="KRQ43_001282"
     CDS             20282..21616
                     /locus_tag="KRQ43_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH2741646.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVLLNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKVGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSKLEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            22113..23039
                     /locus_tag="KRQ43_001283"
     CDS             22113..23039
                     /locus_tag="KRQ43_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HBH2741647.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPNNNKPESNKPEDN
                     NNSDSTNKPDDNNNSGSTSENFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKK
                     SQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGH
                     RKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(23431..26970)
                     /gene="nifJ"
                     /locus_tag="KRQ43_001284"
     CDS             complement(23431..26970)
                     /gene="nifJ"
                     /locus_tag="KRQ43_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBH2741648.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHACIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRIQV
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKVDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVLEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(27488..28057)
                     /locus_tag="KRQ43_001285"
     CDS             complement(27488..28057)
                     /locus_tag="KRQ43_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH2741649.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            complement(28129..28737)
                     /locus_tag="KRQ43_001286"
     CDS             complement(28129..28737)
                     /locus_tag="KRQ43_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH2741650.1"
                     /translation="MDSNDKKGLKSTEIIIINGSPRINKNCSFIANKVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRNKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            complement(28745..30508)
                     /locus_tag="KRQ43_001287"
     CDS             complement(28745..30508)
                     /locus_tag="KRQ43_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HBH2741651.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDTIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMKDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            complement(30551..31018)
                     /locus_tag="KRQ43_001288"
     CDS             complement(30551..31018)
                     /locus_tag="KRQ43_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741652.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMIAFNLNMILGIGVFLIGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            31201..31662
                     /locus_tag="KRQ43_001289"
     CDS             31201..31662
                     /locus_tag="KRQ43_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741653.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQHFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            complement(31755..31925)
                     /locus_tag="KRQ43_001290"
     CDS             complement(31755..31925)
                     /locus_tag="KRQ43_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741654.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(32114..32335)
                     /locus_tag="KRQ43_001291"
     CDS             complement(32114..32335)
                     /locus_tag="KRQ43_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH2741655.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            complement(32419..33645)
                     /locus_tag="KRQ43_001292"
     CDS             complement(32419..33645)
                     /locus_tag="KRQ43_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH2741656.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTRFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINANTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            complement(33707..34639)
                     /locus_tag="KRQ43_001293"
     CDS             complement(33707..34639)
                     /locus_tag="KRQ43_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBH2741657.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIVGWMLGIFFTVIF
                     IKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            complement(34728..35255)
                     /gene="hpt"
                     /locus_tag="KRQ43_001294"
     CDS             complement(34728..35255)
                     /gene="hpt"
                     /locus_tag="KRQ43_001294"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH2741658.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            35484..36560
                     /locus_tag="KRQ43_001295"
     CDS             35484..36560
                     /locus_tag="KRQ43_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH2741659.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            complement(36647..37855)
                     /locus_tag="KRQ43_001296"
     CDS             complement(36647..37855)
                     /locus_tag="KRQ43_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBH2741660.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(38016..38405)
                     /locus_tag="KRQ43_001297"
     CDS             complement(38016..38405)
                     /locus_tag="KRQ43_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HBH2741661.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIIKKDKHSNIIENVEFSIKDEEE"
     gene            complement(38509..39510)
                     /locus_tag="KRQ43_001298"
     CDS             complement(38509..39510)
                     /locus_tag="KRQ43_001298"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBH2741662.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     misc_binding    complement(39569..39824)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(39958..41148)
                     /locus_tag="KRQ43_001299"
     CDS             complement(39958..41148)
                     /locus_tag="KRQ43_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH2741663.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDIVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLVRKGFKH
                     TPLQSLCPEYKDKIITCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     gene            complement(41429..42550)
                     /locus_tag="KRQ43_001300"
     CDS             complement(41429..42550)
                     /locus_tag="KRQ43_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HBH2741664.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMQFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            complement(42611..43096)
                     /locus_tag="KRQ43_001301"
     CDS             complement(42611..43096)
                     /locus_tag="KRQ43_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBH2741665.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            complement(43098..43766)
                     /locus_tag="KRQ43_001302"
     CDS             complement(43098..43766)
                     /locus_tag="KRQ43_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741666.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLASNFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            44156..46180
                     /locus_tag="KRQ43_001303"
     CDS             44156..46180
                     /locus_tag="KRQ43_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2741667.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGEVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKRAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            complement(46410..47597)
                     /locus_tag="KRQ43_001304"
     CDS             complement(46410..47597)
                     /locus_tag="KRQ43_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HBH2741668.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMTKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(47799..49070)
                     /gene="brnQ"
                     /locus_tag="KRQ43_001305"
     CDS             complement(47799..49070)
                     /gene="brnQ"
                     /locus_tag="KRQ43_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH2741669.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAIFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            complement(49211..49864)
                     /locus_tag="KRQ43_001306"
     CDS             complement(49211..49864)
                     /locus_tag="KRQ43_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH2741670.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNSFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDEIRGAIFDVSQAIDLTKLMGIIIK"
     regulatory      50194..50295
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            50368..51711
                     /locus_tag="KRQ43_001307"
     CDS             50368..51711
                     /locus_tag="KRQ43_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH2741671.1"
                     /translation="MVPNTNNVQPDGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            51858..53222
                     /locus_tag="KRQ43_001308"
     CDS             51858..53222
                     /locus_tag="KRQ43_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2741672.1"
                     /translation="MSQLLIKNAYLITMNADREVYETGSILIENNIIKNVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLIRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHNPGAAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(53400..55265)
                     /locus_tag="KRQ43_001309"
     CDS             complement(53400..55265)
                     /locus_tag="KRQ43_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBH2741673.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIEYNKIEFEKEINDILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(55501..56718)
                     /locus_tag="KRQ43_001310"
     CDS             complement(55501..56718)
                     /locus_tag="KRQ43_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2741674.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLIVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(56918..57781)
                     /gene="aroE"
                     /locus_tag="KRQ43_001311"
     CDS             complement(56918..57781)
                     /gene="aroE"
                     /locus_tag="KRQ43_001311"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH2741675.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGIEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNAKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIESSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(57863..59785)
                     /locus_tag="KRQ43_001312"
     CDS             complement(57863..59785)
                     /locus_tag="KRQ43_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH2741676.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDIHDSSVIAAYLEGCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(59864..60712)
                     /locus_tag="KRQ43_001313"
     CDS             complement(59864..60712)
                     /locus_tag="KRQ43_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBH2741677.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGTEEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            61125..62006
                     /locus_tag="KRQ43_001314"
     CDS             61125..62006
                     /locus_tag="KRQ43_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH2741678.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(62214..63077)
                     /locus_tag="KRQ43_001315"
     CDS             complement(62214..63077)
                     /locus_tag="KRQ43_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBH2741679.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(63232..65166)
                     /locus_tag="KRQ43_001316"
     CDS             complement(63232..65166)
                     /locus_tag="KRQ43_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HBH2741680.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKAINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLSV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSLEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(65278..66291)
                     /gene="galE"
                     /locus_tag="KRQ43_001317"
     CDS             complement(65278..66291)
                     /gene="galE"
                     /locus_tag="KRQ43_001317"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBH2741681.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(66316..67185)
                     /gene="galU"
                     /locus_tag="KRQ43_001318"
     CDS             complement(66316..67185)
                     /gene="galU"
                     /locus_tag="KRQ43_001318"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH2741682.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(67383..67703)
                     /locus_tag="KRQ43_001319"
     CDS             complement(67383..67703)
                     /locus_tag="KRQ43_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741683.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(67693..69684)
                     /locus_tag="KRQ43_001320"
     CDS             complement(67693..69684)
                     /locus_tag="KRQ43_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741684.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCDIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKNMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(69806..72349)
                     /locus_tag="KRQ43_001321"
     CDS             complement(69806..72349)
                     /locus_tag="KRQ43_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HBH2741685.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQDKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEGYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGAKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEVEQEEENLNDISPDIILDKPVENHQAKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(72627..72961)
                     /gene="rnpB"
                     /locus_tag="KRQ43_001322"
     ncRNA           complement(72627..72961)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KRQ43_001322"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            73093..73770
                     /gene="srtB"
                     /locus_tag="KRQ43_001323"
     CDS             73093..73770
                     /gene="srtB"
                     /locus_tag="KRQ43_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HBH2741686.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKTSSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKNNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
BASE COUNT        24877 a        12321 c         8652 g        28078 t
ORIGIN      
        1 atagaattta aaaataaaag aagagtattt caaatgattt gtataaatta ttatgaaaaa
       61 ctcttttttt gatataataa aattacttac atatataaca tttaaattta taaattatct
      121 ttttattttt taaaatatgt ataacacacc tatagaaatt actattatta ctatctaaag
      181 tattttgcta taatcccata tactcttacc tcaaaaacat tcaaatggaa aaaatactac
      241 atattaataa actttgccca ataattccta aaataatatc ctaacaatga tttatgtttt
      301 tataatagta tatttttaca taaaaaagtg aacattgatt aacaaagttc acttttttat
      361 aaatttttat gttataattc acaattttat ttaatttgtt tcttttctat ttaaactata
      421 tctatctaat attaattttt catattcttc tattggcatt ggtctagcaa ataaaaatcc
      481 ttgggccata tcacaaccta taaaccttaa aaactctgct tgctctacag tttcaacacc
      541 ttctgaaaca acttttatat caagttgctt tgccatttga acaatacttg aaactacaat
      601 ttgactcttt tttgcatttc ccactgttat aaagaattgc ctatctaatt tcaatacatc
      661 aattggcata tctttaagca tatttaaaga agaataacca gaaccaaaat catccataga
      721 aattttaaat ccaacagatt tcaaagtttg cattatttta aataatattt ttgtattgtc
      781 aaatattgca ctttctgtca attcaatctc aattaaattt ggttcaattt catattcttt
      841 tgttattctt tcaagctcag aaataaaacc tggattctca agatgtactc ttgataagtt
      901 tattgatata ggaaatgtgg ggaaattttc attttcccaa cgtttaaaat ttttacaaac
      961 ttgggcaaat acaaacatat ccaattctgt tataaaacca tttttctcaa aaataggaat
     1021 aaatacacct ggacttatta gacctttttt gggatgttgc caacgtacaa gcgcttcagc
     1081 acctacaatt ttagtagttg ataaatcaac cttaggctgt aaataaactt taaattgttc
     1141 attttttaaa gcatcatgca tttcttgttc aatatcacgt tcttctatga gagtttcttt
     1201 taaattttca gcataaatct cataaacttt taaatatttt ctttttactg tagtttttgc
     1261 aatcatagct ttgtcaagac aggtagaaat atttgtttct ccctcttcaa caaaatatac
     1321 acctatggat ggaattaaat tgagttctac tcccaaactt gtttttatca ttgacaattt
     1381 tttacgtata agttcacata tttctataat tgactctcta ttatttttct tttcaaatat
     1441 tatagcaaaa ttgtcatttg aaattcttga aaatacagat tgctctttaa atatattctt
     1501 aattatctct gctatttcct ttaatactct atctccttct tcatacccaa acctatcatt
     1561 tactagctta aacttatcta tatcaaaata aattaaaact agattctttt tctcatgaga
     1621 ggataaaaat tttcctcctt caagattaaa tttatttgaa ttgccaatac ctgtaacgtt
     1681 atctttaaaa gcaaattctt ccaatttttc cttactcttt ttatgtataa atagtatata
     1741 aattgttaat gccgtaaaga ttataatcaa cactacacat gctgataatg taagttttat
     1801 aatagcgtat gatttctcag atatagcagt tttaggaact tcagaaaaaa gataccaatc
     1861 attgattcct attggggcat aacttaaata atatcctttt ccaaacatac tataacttaa
     1921 tgaacctgat ttaaagtttt ttatatttga cttcatatta ttgatactag attttgatat
     1981 tgaatcactt ctgccaatgt aagaaaataa attttcttta gtagagttgg cgtttttgct
     2041 gcttggattt aaaacaatat taccattact tctagctata taagaatatc cttttccatt
     2101 aaatgtaggt acagaaagta ttttttcata caacttcgta ctatgtgtgg caaatataac
     2161 tcctttaacc tcattatctt tataaattgg cacagaatat acattaatat tactattggt
     2221 atttttatca tcttctatta catcttttaa tttttctgtt ataaccactt ctccttgcat
     2281 tgattttaag aaataatctc ttttagagaa gtcttctata taaccatctg tagtgtatgc
     2341 tgtaccattt ggtaaaataa ctcccattct tttaaatgaa ctattaatag cttgtctttt
     2401 tagtatagaa aggatattat ctacttcaaa agactcttct ccctcaataa atattgaaat
     2461 tgactctagt aactttatat ctccattaat ttgttttttt aacacattga cgctttgatt
     2521 tgctatttct gaaagatatt gattcgtttc ttcacctaat gtcttattca accttgaacc
     2581 ataaatcaaa caggaaattg taattactaa gatacttatg acagcaatta tggacaaacc
     2641 atacctatta ttttttgcat cacttaacat tatgcttcct gcctttctcg aatctatgta
     2701 tgtataatca ttatcttatg acaattattg taaacatttt ataataatac ttatttttcc
     2761 atatttactg taattataca aaattataaa ctttattaca acaataaatt aattaatata
     2821 gatattaggg tttatattat tgcattatct attttacaat catttacata taaaaaaatg
     2881 taatatcaaa gtgaaacttg atattacatt tttgttcttg tattttgttt aatttttatg
     2941 ctacatttta cttaaacact catttgcaac ttctttatca tcaaaatgat gcttaacttt
     3001 acctataatt tgataagttt catgtccctt acctgttata attacaacat catccttttt
     3061 tgccatactt atagcttctg ctatagcttg ttctctatca acaacaacat ggtaattttc
     3121 ttttttcttg tcaattcctt caagtatatc ttttattatt gcctctggtt cttcagttct
     3181 tggattatca gaagttataa tacataaatc agaatatttt tgtccaattg ctcccatcaa
     3241 aggtctcttt tcagtatctc tatctccacc acatccaaac acagaaatta tttttccttc
     3301 tgcaaattgt tgagttgtct ttagtacatt ttcaagtgca tcaggagtat gagcatagtc
     3361 tacaattaca cttatacctt tatcatttgg aactgtttca aaccttcctg atactccatt
     3421 agaaagtcta agaccttctt tatatattgg tttaggtatg ccaagtacat agcaagcagc
     3481 tataactgct aaagtattat atactgtaaa cattcctgga actggtataa atattacttc
     3541 ttcatatgaa ggtgttatta atctataaga tactccatcc gaatctgatt ttatatctct
     3601 agccataaaa tcagccttag tatcaacacc ataagtgtaa caaggtacat ttataccttt
     3661 tatattttca tatatctttt ttccaccttc atcatctatg tttattatat ttgccatagt
     3721 agtcttaaaa aataattttt cttttgcttt tctataatcc tctaaatctt tatgaaaatc
     3781 taaatggtct ggtgttaaat ttgtaaatat gcctagttta aagtctgttt catcaactct
     3841 atttaatgcc aatgaatgtg atgaaacttc catcgcacag tagtcacatc cattatccaa
     3901 catattatta aaatgatatt gtaaatctat actttctgga gttgttgaat tggaaacaat
     3961 gtctttttct ccgtcaaaaa tttttatagt tcctataagt ccaactttat tcttatttaa
     4021 agttaatatc tcatttagta tagtagttat actagttttt ccattagtac ctgtaactcc
     4081 tataacgtta aatttctgag atggatgatt ataaaaatta tcagctactt ttgccatatc
     4141 ttttcttgta tcttttacct ttataaatgt acatcctttt atttctacat cttcttcaac
     4201 aagaaatgca cttgctccct tttctatggc atcttttata tacttatgac catctgacac
     4261 aaatcctttt atacatataa ataatgtacc ttttgtaacc tttcttgaat tatattgtac
     4321 attattaata tctatattta attcaccctt gacattgatt atatccaacc cctgtataat
     4381 atcatttaat ttcataaatg ctttcctccc tttaaactct ttctgctaaa attacactac
     4441 atataatatt atattaagaa ttttttacta tgtgaatggt taaaaatgct tgaaatattg
     4501 caaaaaatgc tctataattt tctataatat aactgaggaa aggtcttcta taaaaactat
     4561 ggataataaa atcgggtact taaacgataa ctttaaaata tttaatatta gagataaaaa
     4621 agatatacaa tttgaatacc ataatcatga ttttaataag ataattatat ttataaatgg
     4681 aaatgtaact tattttgttg atggtattcc ctataaacta aagccttggg atatactctt
     4741 tatcagcaat aatgaaatcc ataaaccagt tatagattca aatgtctttt atgagagaat
     4801 tgcaatatgg attagcccag aatttatgaa aaaaaatagt gatgctacta gtgacttaga
     4861 aaaatgtttt aaaatagcta cggagaataa atgcaataga ttgcgtttaa atatacatga
     4921 tattgaatct attaagagtt ttattgagca aataaatatt tccgaatcca atactgaatt
     4981 tggaaatgaa atattgagaa atgcattatt tatacaactt atgatattct taaacagaat
     5041 tttcctaaaa aatgaaaata tggaatcaac agaagacgtt ttttatgatg aaactattaa
     5101 gaaagtatta aactatataa attcaaatat agatgataag ctttcaatag atagcatatc
     5161 gtctgaattt tttataagta agtattatct tatgagaaaa tttaaatctc atactggaac
     5221 gtctatacac aattatatag ttcaaaaaag attaatttta gcaaagtcac taataaccaa
     5281 tggttacctt atgagtgaag tttgtaataa atgtggattc aacgattatt ctagttttgt
     5341 aagggcattt aaaaaaaact acggtgtatc tcctaaaaat tatataaaca ataaaaatcc
     5401 tttagatatt actcttttag atgaatagat aatttatgta aattttattt taataaaaac
     5461 ttgaagtatt agtgtattta tcttactaat acctcaagtt ttttaatgtt ttaaaatata
     5521 tcaaaatata atgatatata tttctattac ttaaaatata tattaaataa attgcatgtt
     5581 aactgaacct atttatatat ttattaaatc tcacataact tttagttata ctatcatata
     5641 gctatcctat tttttcaata tcatatctta atatacttac tctgttctcc tcttttgctg
     5701 tagttattcc ttttttaatg cttaatttct gattttgttc taaattcgta aatactacag
     5761 gacttattgt tgatagacaa tttttttcaa tatattctaa gtccatttta actaattttt
     5821 ctcctgcttt tacttcatct cctacattca caaatacttc aaatccattt ccttctaaat
     5881 ttacagtttc tatccctaaa tgtataagta tttctactcc actttttttg gattttatta
     5941 ttattgcatg cttagttgga aatataactc caatagttcc atcaactggt gaataaatca
     6001 atccatcact agatttaatt gcaaatccat cccccatcag tttacttgaa aatacagaat
     6061 ctggcacttc ttctatatct aatatctctc catttgttaa tgaatcaatc ttttctacta
     6121 aagcattttc catattggca acttccatat tttttttcac tttattttta tcaacatttt
     6181 tagtaacagt actttcaacc tttgtttttc cctctattat atcttttata tcagacttta
     6241 ttgaatccga ttttggtcca aatatagctt gaacattgtt gccaataacc ataacacctg
     6301 ctgctccaag taatttcaat ttttctttat ctactttatt tatatcattt acaaccaatc
     6361 taagtcttgt tatacacgca tctaggctct ttaagttgtc tttatttcct aaagcaatta
     6421 aaatctctga tgctaattca ttcttagaca tttcaatgac ttcagcgtta gtttctgact
     6481 catcttctct tcctggtgtc tttaaattaa attttcttat cataaatcta aatacactat
     6541 agtataatac tgcaaaacca atacctacca agatagccaa gtaccatgga gttctattag
     6601 gaagaacacc aaataataag aaatctatta atcctcctga aaatgtgaat ccaattttaa
     6661 ctcctaataa ttgcataatt gcgtatgata aacctgaaaa taaacaatgt attgcaaata
     6721 atactggtgc aacaaataaa aacgcaaact ctattggctc ggttattcct gttaaaaaag
     6781 aggttaatgc tgctgatgcc attatacctg ctacaaattt tttcttttct ggctttgctt
     6841 catgcaccat agcaagagct gctgctggaa gaccaaacat cataaatgga aatgcacctg
     6901 tcataaaagt acctgctgtg aaatttactc catctttaag ttgagcaaag aatatctttt
     6961 ggtcacccat tacaagctca ccagctttat ttacatattc tccaaattga taccaaaatg
     7021 gattatggaa aacatgatgc aaaccaaatg gtattaatag tctttccaaa gaaccttcca
     7081 taaatgctgc tagtgtttga tttgcttcta taacattttt tgagaaacta agtaatccct
     7141 cttgtattgg aggccaaata aaagacaata taattcctat tgctatagca actaatgaag
     7201 taacgattgg tacaaatctt ttacctgcaa aaaaacctag atactgaggt aattcaattt
     7261 tataaaactt tttataaaga taagcagcca ctatccctat aataatacca ccaaataccc
     7321 ctgtttgaat tgttggtatt ccaacaatac ttgcatacat agaattgtct accatatctt
     7381 ctgtaacacc cgccataaca cccatagatg tattgagaat taaaaaacct actatggctg
     7441 ccaatgctgc aacaccttct ccttcagtta aaccaacagc taccccaact gcaaatataa
     7501 gtggtaagtt attaaatata atttgacctg aactttccat tatacttatt ataagttgaa
     7561 atgtaggatt cgccaaagct ggaaaatgag acaacaatgc gtctcctgct aaagcattac
     7621 tcacgccaag taatatacct gctgcaggaa gtaatgcaac tggtagcatt agagattttc
     7681 ctactttttg taaaacacca aatacttttt tcatttactt ttctctcctt attattttat
     7741 atttttttaa ataaaaaaga cttaagttta taaaaagtta cattagtata cttaattcta
     7801 aaattaaact tatgttaata taaataaacc tatattaacc taatttcaga attaaaaata
     7861 aactattata atttttttat aaacataagt cttgcctgca ttatcagtaa caatcttaat
     7921 gttttaaaat tattatttta tattaaattt taaataatat attaaaatta aacataatat
     7981 attaaaccta tacattctgt attaaactac tctttattat aaattcagta cagatataac
     8041 tcttttgata tgtaatgtta aataaagtag ttcatcttga cttacatagt aatcataatt
     8101 cttttctaca tgagttttta ttttatatgc acaatcataa tccttttcat actttacttt
     8161 aattatatct ataatttcat tatttgtatc attgattttt tcttttttta ctaatcgttt
     8221 tgcaaagaat tttaaatgag tcaaaagcct atcataattt atatcatctt ctttaaattc
     8281 aactctataa taatatctta taatatttag tatgtctttt acaattttag taattaacag
     8341 tgattccttt gaacttccct tatagtttga atttactata tgcattgcta taaaaccagc
     8401 ttcatctact ggaaatttca catcaaattc tttatttata taatctacag cccatttacc
     8461 aatctcatat tcttttttat gtattctttt tatctcatgt agtaaatcat tctttatagt
     8521 tatattttca tgatatcttt taattgcaaa tgcaatatgg tcagtaagtg ctacataaat
     8581 atattcataa agcttagtat tcaaattctc ctctgcataa gcaattattt cagtactaat
     8641 ctcaaaaaat ttctcatcaa cctggcttgc tagtttgcta attttatcta aaaagctttc
     8701 atcttgtatt acaaaagttc tttcaatttt acttttatct atttcttgac ctttcttttt
     8761 ttgaaaccca atcccacatc ctgttagtat taattctttt tttatatttt catctaaaac
     8821 taatacaaca ttattattat aaatttgttg aataatcata atcaatatct ctcccaaaat
     8881 acaatttccc ttattcataa aaaaatacct aaattaagat acaattcacc tgtatacctt
     8941 aacctaggta ttgcctgctt accagtaaca atccagcttg ttaattctta tatattgtat
     9001 tcaatttatg gttttattct attataaata aatatatatg tcaagtaaat tattgaaaac
     9061 tatttcctat tttttagtat tatttttaac atcaaaaatc aaattttatt ccattatatt
     9121 tatgattcta tcatcatcat ttaataaaga ttcaccttca agtatactca tcatattttt
     9181 aggaaaattt aatccttgtg tgattgattt tactgctact aaatcagttg aagatattac
     9241 tgctgccaaa gcaagtgaaa cagataatgg catcctagga ataagaaaat gtataaagat
     9301 tccacctgca aacacggtta tcaaaactaa accaaatgca agaagcaaaa ttggttttct
     9361 aagctctagt aactcttttc ttgatacatt ttgtccttca ctgaataata atggagctat
     9421 gatacatatt acaaatattt ctggattaaa tgaaaatgat aatttaaacg gcaaaataga
     9481 caatataatc cctagtacaa tttgatatat tgcaagagga atattactcc actttttgct
     9541 aaatacagtt gaaatctttg tacaaaccaa taatcccaac aatgttacta aagttgacat
     9601 aactacctct cttttcaata ataatattat aaattaaact tatatatcaa ctaacttaat
     9661 attaacaaca tgaaatccca tcttaatcaa aaaaattttc agtttattct attattctta
     9721 ttatatacat caaatttaat ttttgaaata tctatactag atggcatgca acaaaatgat
     9781 ttcttgatat ttcttttaaa actggaatct cttttttgca tatttcctta caataagggc
     9841 atcttgtatg aaacttacat ccacttggtg gatttgttgg agatggtatg tctcctttta
     9901 atataattct atttttctta attgtagggt cttgtactgg tactgcgctc ataagtgctc
     9961 ttgtatatgg atgttgagaa tgtaagtaaa gttctccttt agttgcaatt tctattatag
    10021 aacctagata cataacacaa actctatgtg caatatgatt tactacactc aaatcatgag
    10081 atataaataa atatgagagt ttatatttat cctgtaaatc cataagtaaa tttataattt
    10141 gagattgaat agaaacatct agtgcagaaa caggttcatc acaaactata aattctggat
    10201 ttaatgctaa tgctcttgct atacctatcc tctgtctttg acctccagaa aactcatctg
    10261 gttttctatt taaatggtac ttagaaagac cacaactttc tacaacattt aatatattat
    10321 cttttatttc attctttggc actaaattat gttctataac tgcctctgat attatttgtt
    10381 ccacatttaa tcttggattt aatgaactat atgggtcttg aaatatcatt tgcattttgg
    10441 gtcttaactt tctaagttct tccttctcta acttatatat atctacacca ttaaattcaa
    10501 ctttaccttc agttttttca attaatctaa ggatggttct tcctgcagtt gattttccac
    10561 atcccgattc tccaactata gccaaagttt ctcctttttt taaatcaaaa gaaattccat
    10621 ctactgcctt tacacattta atttccttat caaataatcc agatttaact tcaaagtact
    10681 ttttaagacc ttctactttt aataaactct cttctttttt caattatatc tcctcctttt
    10741 tatataacca acatgcaata ctatgaccac tattcaattc tattaaagga ggtatctgag
    10801 ttctacattt atcacatact ttttcacatc tatcactaaa ataacatgaa tctggtattc
    10861 caattggatt tggtacttgt cctggaatcg aatacaatct tttatctttg ttttttccaa
    10921 gaacaggctt tgattttaga agtccaatag tataaggatg ttttggattt ttaaataatt
    10981 caacaacctc tgccacttct ataattttac cagcatacat cactaatact ttgtcacaca
    11041 tttctgcaac tactcccaaa tcatgtgtga tcatcattat agatgtgttt aatttttctt
    11101 ttatattttt cattatatct aaaatctgag cttgaatagt aacatctaaa gctgttgttg
    11161 gttcatcagc tataagtaat tttggattac atgataaagc catagctatc attattcgtt
    11221 gtctcatacc acctgataat tcatgtggat atgaattata tatttcttca gctcttggta
    11281 tttctaccag ttttatcata tcgattacct ttttcttagc ttcttccttt gataaatctt
    11341 gatgtatcat aataccttca atgatttgac ttccaacagt gaacgctggg tttaaagatg
    11401 tcattggttc ttgaaaaatc attgatatct cattccctct tattaccata agttcatctt
    11461 cattcatctt taaaatgtct ttgcctcgaa agattatttc tccaccttct atttttgatg
    11521 ttggaagtaa cttcatcaaa gacatggctg ttacagactt accacatcct gattctccaa
    11581 ctattccaat agtttcacct tcatttatat taaaacttac ttcatttaca ctctttacaa
    11641 tccctttatc tgtatgaaaa taaactttta aatctttaac ctcaattagt gctttactca
    11701 ttattttctc ctctcagcaa aattacttaa aataacatac accttttgat tgtattttat
    11761 aaaaatttaa attacaacat tttcttacat tttattattt ttttctatta attataataa
    11821 tataatagtt aatttctata tatattgatt taataatgat tactattata caatgaaaaa
    11881 tatgtgttaa atattatttt atggaggttt tataagaata tgaaatttaa aaaattggca
    11941 tcattaatct tagtttcatc attaatgctt acatttacag cctgtgcttc caatgataaa
    12001 gacaagtcta gtggaagcaa atctggtgga actgttgtaa tacctatggc aagtgaccca
    12061 gatataatca atggagcttt tgcaaacgtt aaagaagact ctcttgcatc aaatatagtt
    12121 tatgctcctc tttatactta tgaaaaaggg aatttagtaa attatttagc agaaaaagta
    12181 gattttaaag atagtaagga attaactata aaattaaaat ccaatttaaa atggcatgat
    12241 ggaaaaccaa taactgctga agatgtctta tttacattta atacagtttt agacgaaaaa
    12301 caaaattcac catcaagaca atacttattg gtgggtgaaa aaccagttaa agtagaaaaa
    12361 attgatgatt taacagttaa gattacttta ccaactgcaa gtgaatcttt cttatatggt
    12421 atatctaaaa tttctccaat accaaaacat gtatttgaag gagaatcaaa tatagctaag
    12481 tcagaaaaaa ataataatcc agttggttct ggtgcattca agtttaagga atggaaaaaa
    12541 ggtgaaagca tagtatttga aaagaatgca gattattttg gtggagaacc taaggcagat
    12601 tctatagcgc taaaaataat tcctaatgaa gcatctcaag aagcagcttt aaataatggc
    12661 gaaatttcac ttatgaagac atctgctgaa ggatatgaaa aggcaaaatc aaactcaaac
    12721 ttacaaactt atacttatag tgaagaaaga ttaaactaca ttgtatttaa ccaaaatata
    12781 tcaaacatgg ctaacaaaga agtaagacaa gccttatcat atgccttaaa tagaaatgaa
    12841 atgatagaat cagcatatgg aaaagaaggt tctgtacctg ctaaatctat attagttcca
    12901 gaagcagact tctatacaga agaaggtgtt gaaggatatg accaagatac aaataaggct
    12961 aaagacttat tggataaaag tggtgttaaa attgataaat taaaaatagg ttataacaca
    13021 ggtagatttg ggcataaaaa ctatgcctta gtagctcaac aagagttgaa aaaaattggt
    13081 atagaagctg aaatagttcc ttatgaaagt aaggcattct ttaatatact atttagtaat
    13141 agcactgaat gtgatatgta tgtaaatggt tatgcttggg gattagaacc aaacccatat
    13201 agaggtatgt ttgaaactgg tcaatattgc aaccaaacta aatattctaa tgctgaaata
    13261 gatgctttat gggaaaaagg atttactgag ttaaacaagg aaaaacgtaa agaaatatac
    13321 aaacaaatac aacaggatat atctaaggat gcacctattt acactataga ttatgaacaa
    13381 aatttaatgg cagctcaaaa aaatctaaaa ggaataaaag atgctaaacc atctcctgca
    13441 atattatttg aagattggtc taaactgtat gtagaataat tgatgtaaaa ttttatatta
    13501 ttaattagaa aaggagatgt ctaaaaataa tattgtttta ttattttaaa acgagacatc
    13561 tcttttaatt aggagaattt acttatgtta aaattaatat tgaatagagt aaaagtttta
    13621 atacctatgt taatcttaat atctatatta tcatttggac ttttagaatt agctcctggt
    13681 gacccagcag atgcatatat aaatccttta atgtcttcac aggatattga aaatataagg
    13741 gttaatatgg ggcttgataa accagtatat ataagatatt taaactggtt gaaaaacact
    13801 ttaagtggaa acttaggtat ttcttatata aaccatatgc ccgttacaga acaaattatg
    13861 gaaaaaatgg gaaatacatt tattcttatg ggtacttctt tgatattttc aatattggta
    13921 gctatacctc ttggaatatt tttagctgta aataaaaatt caataactag taaagtatca
    13981 tctgttttta attatatagg tgtttctatc ccttcttttt ggataggtat gatactcatt
    14041 tcaatttttt cagttaaact taacattttc ccatcaggag gtatgcatac tattggaaat
    14101 gatagtattg gagatttagt aaaacattta gttttgcctg taataacttt aggtctatat
    14161 aatactgcta tttttacaaa ttatgtagaa gctagtgtaa atgaacaatt aaaaaaacaa
    14221 tatgttatta cagcaagagc aaaaggatta tcagaaaaag tcatactatt taaacatgtc
    14281 ttgaaaaatt cactgacatc attggttaca atcctaggca tgagtataca aaaattagtc
    14341 actggtgcat ttgttacaga agtagttttc tcttggccag gtatgggaag attaatgatt
    14401 gattcaattt tttcaagaga ttatactgta attatggcaa taactatgtt atcagcacta
    14461 tttttaattt taggtaattt agttgctgat atactatact tattaattga ccctaaaata
    14521 aaatctagca aaggaggatt ctagttgtgt ttacaagtat cttaaaaaaa ttaaaaaaag
    14581 ataaatcctt tgcttttgca tgtattactc ttagcataat aatcatatta attatagctt
    14641 cttttatatt aaatatagac tctaatgcaa ttgatactac ttctaaactt caagaaccta
    14701 gcttaaagca tatctttggt acagacgaac ttggtagaga ttacttctct agagctcttt
    14761 atggtggaag gatttcactt agtgttggta ttttatcaat gcttatctct gtagtatttg
    14821 gtactgctgt aggtgttatt agtggatata ttggaggtaa gctagaccaa ttcttgatga
    14881 gattagtaga tatgcttatg agtataccaa gtttcttagt tttgattgta ttaaatactt
    14941 atctaacacc taaagtttcc actattatac taattattgg attcttaagt tggatggaag
    15001 tttcaagaat tgtacgtggc gaaacattaa aaataaagga aaatgaatac tgtttagctg
    15061 ctaaagctac tggtatcaag actagaaata tactattaag acatatagtt ttaaacttaa
    15121 aagagactat tgtagtcgct ggttcgttaa atattgctaa tgctatctta actgaatccg
    15181 ctcttagttt tttaggtctt ggaatccaat tacctcttgc atcatggggt aatatgcttc
    15241 aagatgctca aagacatatt tttgacaagt tatatttagc tgtatttcca ggattactta
    15301 tatttttaac agtcataagt ttgactataa taagcaaaaa attttctagt aatacttaac
    15361 aaattttata tagaaaataa aaacagtgat tatctaaaga tatacactgt ttttattttt
    15421 cgtttaaaaa atacatattt tgtatattat aactttaaat actactctac catgttatgt
    15481 aaagcctatt attgctctca aacatataga tgaaaaacta atagtttatt gtaataaaaa
    15541 ttgatttatt tatttgttat tttaataaca tttttaagag ttctttttac taaagaaatc
    15601 tataataaat ttaaatacat gttggtctac atggctataa cgttcttttt taggtctaca
    15661 tagtataact ttccatgtaa taggatgatt aaaaggcttt tctataattt tgctattttc
    15721 aaaaaaatca tgaactggtg atggtaaaat tgttataaaa tcagaatttg tggttgatag
    15781 caacaaaaaa tcccatgaac cagacattat atatcttttt aacttaacat tttcatcagt
    15841 aaatttttgc attagcttat gatgtatcat aaaagtagga ttaaatattg caagtaattg
    15901 ctcattcaaa tcgttccaat ctatcttatc cttcttagca agtggatgat ttatatttaa
    15961 aaatgctgta agttcatctt cttgaagcac atgttcagtt actacacttt tatcaatttt
    16021 atgtggatgt aacagtactg cataatctag ttcctgcaag ataagcattc tatttaagtc
    16081 atatgcaccc ttctctacta tatcaaattc tatatctgga ttatttgcaa ctaactgtgc
    16141 aactacatct gaaaatgcta ttccaagtat aagtggaggt attcctattc taacttttcc
    16201 tttaaattga actgaatctt ctcttaaatc ttccatcata tttttgtatt catttataat
    16261 atgttctgca tttacataaa atctttctcc tgctggtgtt aacccattta acctaccttt
    16321 atacctttca aataaatata catcttcact ttcttcaaaa ttttttataa tttgacttaa
    16381 tgctggttga gatatgtgaa gtgtcttaga tgctattgat aaattaaaac cagatttcac
    16441 tatttcaaca aaatatttca actgttttat atccatttta aacccccttc cccaaaagta
    16501 taatttagat tatatttttt cttctaatga tattttatag gaaaatcaac ataatttcat
    16561 taatatttta acaaaatatt tttctaaatc tactataaat ttttatccta taaatttttc
    16621 ttatacacta tataaaaaat tagacttaga caaaatgctt ttttcgccgt aatctataat
    16681 tagaaacagg aaaacctaaa gcattaggaa taaaagtaat tgaaatactt aaaaacaagc
    16741 ttgtattaaa aaagtacttt attatagtgt tccctaattt ctttattcag aaaattttta
    16801 attatcattc aagaaaggta actattagat atgaaagatg tagtaatcgt atcagcagtc
    16861 agaacaccta taggaagttt tggaggtgta tttaaaaata cttcagctgt tcaacttgga
    16921 actatcgctg ttaaagaagc gatatcacgt gtaggactta atttatctga aatagatgaa
    16981 gtaataattg gaaatgttct tcaaacaggg cttggacaga atgttgctag gcaaattgct
    17041 ataaattcag gtataccaaa ttctgttcca agctacacag taaataaatt atgtggttca
    17101 gggcttaaaa gtgttcagct agctgcccaa tcaatcacat ctggtgaaaa tgatgtggta
    17161 attgcaggtg gtactgaaaa tatgagccaa gctccttata tcgttccaac tgctcgcttt
    17221 ggtagtaaaa tgggtgacat aaccatggta gatagtatgc taacagatgg ccttattgat
    17281 gctttcaatc agtatcatat gggaataact gcagaaaata ttgcaactaa atttgaattt
    17341 actagagaaa tgcaagataa attggcatta gaaagtcaaa ataaggctga gaatgctata
    17401 aaaaacaacc gctttaaaga agaaatcgtt ccagtagatg ttttaatacg tcgaggaaaa
    17461 atagaaacta ttgataaaga tgaatatcct aaattaggca tgacatttga aggtttagct
    17521 aaacttaaac ctgcattcaa aaaagatggt actgtaacag ctggaaatgc ctcaggtatt
    17581 aatgatggtg cggctatgtt aatactaatg agccaacaaa aagcagacga actaggtatt
    17641 agaccacttg ctaaaataaa atcctatgct tcagctggtg ttgaacctga agtcatgggt
    17701 actggtccaa tccctgcaac tagaaaagca ctgaaaaaag ctggacttag catcaatgat
    17761 atagacttaa tagaagcaaa cgaagcgttt gctgcccaag cattagctgt taaaaatgaa
    17821 cttcaaatag attcatcaaa gttaaatgtt aatggtggtg caatagcatt aggacatcca
    17881 ataggagcaa gtggagctag aatacttgtt accttaattt atgaaatgca aaaacgtaaa
    17941 gttgaaactg gacttgcaac actttgtatt ggtggtggtc aaggaatatc aatggtggtt
    18001 tcacgatagg aggaaatatg aataaaatag ttagcattga tgaagctcta tctcatgtaa
    18061 aagatggaga tacaataatg gttggtggat tcatggccaa tggttcacca gaaaatttaa
    18121 ttgattattt atgtagtaaa aatataaaag atttgacact aatttgcaat gatactggct
    18181 ttattgacaa aggagttggc aaaatggttg taaataagca atttaaaaag ataattgctt
    18241 ctcatgtagg attaaataaa gaaactggaa gacaaatgaa caacaatgaa acagatgttg
    18301 agttagttcc tcagggaact cttgctgaac aaatacgtgc agctggttat ggtctaggag
    18361 gtatactcac accgactggt attggtactc ttgttgagga gggaaagcaa aaaattgttg
    18421 tcgatagcaa agaatacctt cttgaaaaac caatttatgc agatgttgct cttctatttg
    18481 catcaaaggt cgataaagca ggtaatctag tttataaagg ctctatgaac aattttaata
    18541 atttaatggc atctgctgcc aaaattacaa tagttgaagc agatgaaatc gttgaaattg
    18601 gtgacattga cccaaatgaa gttaatacac caggtatttt tgtgaattac atcgttgaag
    18661 gaggtaattt ataatggata aattagaaat gcaagaatat attgcaaata gagtatctaa
    18721 agaattaaaa gacggagccg ttgtaaacct tggaataggt ctaccaacca aagtagcaaa
    18781 ttatattccg gataatgtaa acgttatctt acaatctgaa aatggctttt taggtttagg
    18841 ttcagccgaa gatggaaatt caagtgatga aactattgta aatgcaggtg gtcaaccagt
    18901 tactatactt cctggaggat gtttctttga tagtgctact tcttttggaa taatcagagg
    18961 aggtcatgtt gatataacta ttcttggcgc acttcaggtt gacaaatatg gcaatatagc
    19021 aaactatatg attccaggta agatggttcc aggtatgggt ggagctatgg acctagtaac
    19081 tggagctaaa aaagttattg tagcaatgga acatacttca aaaggttctg caaaaatatt
    19141 aaataattgt actcttccac ttactgcaac aaatgctgta gatttgatag ttactgaaat
    19201 gggagttatg gaagtaacat cagatggaat tttacttaaa gaaataaatc cagctttcac
    19261 attagatgat gttatttctg ctactgaagc tcctttaata ttgtcagatt cattaaatgg
    19321 aaaaatatct gttgtttaaa ataattaaaa ctagaaaata aaaatctctt agacgtatta
    19381 catataaatt tgtattgctt aaaatattaa tataaaaata aaataaaatt ggaggaaatg
    19441 aaaatggtta aagataaagt tgtattcgta acaggagctg caagtggaat aggtaaacaa
    19501 atagctgaat cgttcttaaa aaatggtgct aaagtaatgt tctctgatat aaatcaagaa
    19561 gctttaaata ataccataac agagttacaa aaaaaaggtt atgattgcat gagtgtaaag
    19621 tgtgatgtaa ctaaggaaga agaaattaac cacgctatag ataaaactgt tgaaaagtat
    19681 ggcagattag atatattaat aaacaatgct ggacttcaac atgtttctat gatagaagat
    19741 ttcccaactg ataaatttga atttatgata aaaataatgc tgacagcacc ttttatagct
    19801 actaaaaaag catttcctat aatgaaaaaa caaggctttg gtcgtataat aaatatggcc
    19861 tcaatcaatg gtgtaatagg atttgctgga aaggctgctt ataactcagc aaaacatgga
    19921 cttattggac taacaaaagt tgctgctctt gaagctgccg attctggtat aacagttaat
    19981 gctttatgcc ctggatatgt agatactcca cttgtcagag gtcagtttaa tgacctttca
    20041 aaaactcgta atataccatt agaaaatgtc ttagaggaag ttttgtaccc acttgtacca
    20101 caaaaacgcc tattagatgt tcaagaaatt gccgactatg ctatgttcct agcaagtgat
    20161 aatgctaagg gtattacagg acaagcttgc ttactagatg gaggatatac tgcacaatag
    20221 ttattatatt tagggcttga agaaagtatt cttcaggtcc ttctactaag gagggatatt
    20281 tatgagtatt atcgcaccaa ttggtataat tattggtatc atagctatta tatatttttc
    20341 agttaaagaa attcatataa ctatagctgc tccaatagca actttaatag ttgttctctt
    20401 aaataaaatg gatgttgtaa catcaatgct aggtgctgac aaaaacaatt atatgggtgc
    20461 acttggaaac tatataatga gttattttgc aatattctta ttaggctcaa tacttgctaa
    20521 atttatggaa gaaagtggag ccactgtatc aatagctgat tttattttaa ataaagttgg
    20581 ctctaatcat ccttatagag ttttagttgc tatatttata gtaagtttta tattaacgta
    20641 tggtggtata agcttatttg tagttatgtt tgcagtcatt ccacttgcaa gaactctatt
    20701 taaaaaactt gatatttctt ggaaccttat tcagatacca ctttggcttg gtattgcaac
    20761 aattactatg actataattc ctggaacacc agccattcaa aatgttatac ctattcaata
    20821 tctaaatacg tctcttactg cagctactat accaagtatt gtaggtagta taggttgtgc
    20881 tacgtttgga cttgtctata tgaaatatgc tctaaacaaa agtattagaa aaggtgaaac
    20941 ttacgcaact tacacttcaa aattagaaga agaatcttta gatagagaat taccaggatt
    21001 ttttgcaagt atttttcctc tattagcact cgtaattata gctataactg gaagtacttt
    21061 tggttcagaa tttatgaaaa aaaatgtaat ttacatagct ttaatagttg caattctttt
    21121 atctgctttt ttattccata aatttctatc atctaagata cagacattga gcataggtgc
    21181 tagtggttct ataggtccta tatttgctac atcttctgca gttgcatttg gagcagtaat
    21241 aatggctgca cctggttttg atgtatttag caaacttata atgtcaatac caggtagtcc
    21301 acttataagt cttactgttt tgacttcaac aatgtcagca ataacagggt cctcttctgg
    21361 tgcattagga atagtaatgc caaactttgc agattattat ttaagtactg gtctaaatcc
    21421 agaattaatt caccgtgttg ctacaatagc ctcaaatata ctaactatag ttccacaaag
    21481 tggtgttttt cttacattct taagcttatc taagttaaca cataaaactg gatttaaaga
    21541 aactttcatt gtagttgcag ttggttcact aatagcagaa attattgtaa ttacattagg
    21601 attactaatg tattaatata aaacaaatta aaattcataa tatgaaaggt ggtgtctcaa
    21661 agtgaacttt ttacttaatg agacactctt tttgtatgaa atcaaatata ttttaatcat
    21721 ttcaacaata aaaaagaacc tttctctatt ttgagacaaa ccctttttat tccttaaaga
    21781 tttaaacaat tataatttgt tactaatacg aaaacatcta ttgaataaat ttaaccaaat
    21841 aaaaaaaaat ttatcataac tataaattta cgttatggaa ttattataaa aatattattt
    21901 tctctaagta agtaattcca tactatacag gcttttaata caaattttca aacacactga
    21961 aatataccta tttattccat atatatcttt tttacatatc tttacagtaa aaaaagtctt
    22021 aatcttatgt tagtatagat tcacgggtac cccctacact aaaggttaca aatcagtaac
    22081 atttttagaa tttttagatt aagaggtgtt taatgatgag aagaaatata ccaacaaaat
    22141 taaaaactat attagcttta ggagtgttaa ctttagcaac agcttcaagt gctgttactg
    22201 caagtgcttc atcacttgaa aataatgtaa atataagtaa caaaagttta gtatatagta
    22261 atactaaata caagttttct gcaaaaccaa attgttctgt aaaaccagaa cttaaacctg
    22321 ataaagataa ctcttgtaag gataagaatc ataatgacaa gaattgcaac aacactaata
    22381 aacctgagga caacaataat tcagactcta ctaataagcc tgataacaat aaaccagagt
    22441 ctaataaacc tgaggacaac aataattcag gctctactaa taaacctgat aacaataaac
    22501 cagagtctaa taaacctgaa gacaacaata actcaggctc tactgataaa cctaataaca
    22561 ataaaccaga gtctaataaa cctgaagaca acaataattc agactctact aacaaacctg
    22621 atgataataa caactcaggc tctacaagtg aaaatttttc agcttaccaa aaagaagttg
    22681 tcgacttagt aaatatagaa agagctaaag ctggattaaa tcctcttact cttgattctt
    22741 ctatatcaaa tgttgctaca aaaaaatctc aagatatgat tgataacaac tatttttcac
    22801 acaattctcc aacttatggt tctccatttg acatgttgaa aaaatttgga ataagctata
    22861 agacagcagg tgaaaatata gctatgggtc aaaaaactcc taaagaagtt gtaaacgcat
    22921 ggatgaattc tgaaggtcac agaaaaaata taatgaatcc aaatttcagt aaaataggtg
    22981 ttggagtagc acaaaaaagt ggtggttcaa tttattggac acaaatcttt gtaggataaa
    23041 atactctttt tccatgcata tcaaaagagt atctctaagt gataaaaaac acaaatgaga
    23101 tactcttttg tatctatttt aaaattatca aatccaaata tacatactat aaatattatt
    23161 tgttctctta attttagtgt gtagaacaat atataaaaag tattggcaag atgaaaatgg
    23221 aaaacttaaa aagatattta ataggtaaaa acaggatctt aatatcttca taaaaaaagg
    23281 ctgtctcaaa atagagataa ggcctttttc attgttgaaa tgattaaaat atatttgatt
    23341 tcatacaaaa agagtgcctc atgaactaaa aagctcactt tgagacactc tcttttatca
    23401 attctatata agcattataa tactttaata ttattcagct aattttttgt atccttcata
    23461 tctttcttta gcatcagctt cagctttagc aaataatcca tcagcttcct ctgggaattg
    23521 tttagctata gcagaatatc ttacttgtgc aagtatgaaa tctttgaagc ttgcagttgg
    23581 ttcttttgaa tctaaagtga atgggttttt accttcagct tttacttctg gattgaatct
    23641 gtataaatgc cagtatccgc aagcaacagc ttgtgcttca ttagccacag ttcttcccat
    23701 accttctttt aatccatggt ttatacatgg agcataagct attattagag atggcccatc
    23761 atgtttttca gcttctaaaa cggctttgat aaattgattt ttatcagccc ccatagcaac
    23821 ttgagctaca tatacgtttc catatgtcat agccatcatt cctaaatctt tctttctaga
    23881 ttttttacct gaagcagcaa acttagccat agcagcagct ggagtagctt tagaagcttg
    23941 acctcctgta tttgaatata cttctgtatc aaatacaagt acgtttacat cttcaccaga
    24001 tgcaagaaca tggtctaatc caccgtaacc aatatcatat gcccaaccgt ctccacctag
    24061 tatccattga gatctcttaa ctagataatc ttttctatct tttatagctt ttactaattc
    24121 tttagctttt tcatctgtac aatcacaagc tggtttttct aataattcaa caaccttagc
    24181 acttgctact ttagaagctt ctccatcatt tctagaatct aaccactctg taaatactgc
    24241 tttagcatct tcacagatat ccatagaaac taactctgtc atagcatcta ctattttatt
    24301 tcttatttgc ttaacagctg tgtacatacc aaatccatat tcagcattat cctcgaataa
    24361 agaatttgcc caagatggac ctttaccttc atggttacaa gtataaggaa ttgatggtgc
    24421 agaagctccc catatagaag aacatccagt agcattagct atcatcattc tatctccata
    24481 taattgtgta actactttaa tgtacgcagt ttctccacat ccagcacatg ctcctgaaaa
    24541 ctccattaat ggttgtctaa attgacttcc tttaacagta tttgcaggca taacatcaac
    24601 ttttggagct acttcatcag gatttactgc aaatgcccaa ttatctaact ctgtatcaag
    24661 ttgagtatct attggcttca taactaaagc tttttcttta gctggacata tgtcagcaca
    24721 gtttccacat cctgtacagt caagtggact aacttgaatt ctatatttta atccttctaa
    24781 tcctttacct aatgcttttt tagcttcaaa tccttctgga gcattagcta attcttcttc
    24841 agtaactaat actggtctta tacatgcatg aggacatata aaagaacatt ggttacattg
    24901 aatacagtta tctattatcc attcaggaac atcaacagct ataccacgtt tttcataagc
    24961 tgcagtacca caagggaatg ttccatcttc tataccattg aatgtactta ctggtaagtt
    25021 gtttccttct tgtgcagtca ttggtcttag tatatttttt ataaattctg gttctttaac
    25081 ttctccttta tctgcatcaa cagcattttc ccaagaagct ggaacttcaa ctttaactaa
    25141 agcatttatt cctgcatcaa cagcagcata gttcatatta actatttttt cacctttttt
    25201 accataagct ttaactatag aatcttttaa gtatttaaca gcatcttctt ctggtattat
    25261 ttcagctaat ttaaagaatg cagattgcat tatcatgttt attctgtttc caagacctat
    25321 ttcttgtcct agtttaacag cattaactgt atagaatttt atatcatttt tagctatata
    25381 ttgtttcata tgagctggta aatgttcttc aagtcctgct tggtcccata tagtgttaag
    25441 tacaaatgta ccaccttttt taagaccttt taataaatca tattgataaa catatgattg
    25501 tttatgacag gcaatataat cagcttcatc tattaaataa gtagctctta ttggagtatc
    25561 accaaatctt aagtgagaca tagttatacc accagatttt ttagagtcat aatcaaagta
    25621 agcttgagca tatttttcag tatggtcacc gattattttg atagcttgtt tattagctcc
    25681 aacagtaccg tcagaaccta atccccagaa cttacatctt atagttcctt tagaagctat
    25741 ttttattggc tcagatggag ttaaagaagt attagttaca tcatcaacta tacctactgt
    25801 aaatccattt ttaggttgtt ctgaaactaa gttatcaaaa acagttttta tatctgaagg
    25861 agtagtatct tttgaaccta atccgtatct tccacctatt atcataggag cattttcttt
    25921 tccatagaat acatcacgta catctaagta taatggttca ccagttgaac ctggctcttt
    25981 agttctatca agtacacata ttctttcaac agtagatggc atagcatcta agaaatgttt
    26041 cattgagaat ggtctatata aatgaacttt aactaaacca tatttttctc ccttagcatt
    26101 taagtaatct atagtttctt ctattgtttc tgttactgaa cccatagcta ttaatacgta
    26161 tttagcatct tctgctccat agtaatcaaa taaactatgt tttctacctg ttaaattact
    26221 cattttttcc atgtattttt caactatacc tactatattt tgatagtatt tattagaagc
    26281 ttctctagtt tggaaatata tatctgggtt ttgagcagta ccacgagcaa ctggatgatt
    26341 tggagataaa gcattatctc taaatgcttg aactgcttca aagtttaata aacttgcata
    26401 atcttcattt tctagtaatt caactttttg gatttcatgt gaagttctga atccatcaaa
    26461 gaaatgtata aatggtaatc taccttctat tgcagctaaa tgtgcaacag gtgctatatc
    26521 agctacttct tgaactgaac cagaagctaa taatacacat ccagtttgtc tagcagccat
    26581 aacgtcttgg tgatccccaa atattgataa cgcttgagat gccaaagcac gagcacttac
    26641 atggaatact cctggtaata actctcctgc aactttatac atgttaggta tcattaataa
    26701 taaaccttga gatgctgtaa aagtagaagt taaagctcct ccttgtaaag aaccgtggaa
    26761 tgttcctgat gcacctgctt ctgactgcat ttcaacaaca ttaactgttt gtccaaatat
    26821 attttttctt ccttgtgatg cccactcatc aactacttca gccatagttg aagatggtgt
    26881 gattggatat atagctgcta catctgtaaa cgcataggca acatgagctg cagctgtatt
    26941 tccatcaagt gttttcataa acttagccat aatatgtatc ctccttgata gctacaattg
    27001 tacttgttta taacaagtct atttttttat atttacatat aatttacaca acaaaaatat
    27061 aaacacacat atagtcgcgc aaatactcta tcttctaata taatactaca gattagataa
    27121 aattcctttg aaaattgtaa attaattaca tatttaagta gatttttttt aaaattaaat
    27181 atgttaagtt tttttcataa ttttgtatac aatatataat aaattaagtt agacttttca
    27241 aactttttta tctatttgtt tacattagta taaaaagtaa aataattatc tttattatat
    27301 gtaaattttt atatatataa ttttaccata ttacatcata tttttgtaag tttttattac
    27361 attttttata ataccccttt attttataaa ttaatctaat cgattaaatt tatcctatag
    27421 aaatttatta catttaaaaa tatgctagca aataaaatat ctactagcat aaagtctatt
    27481 tataatatta atcaactatt aattctacta aatctccatt tttaacgcct gctgcatttc
    27541 cctcttccat atcaacatgc atttctagat taaagctatc actagctctt actaatacat
    27601 tttcaaatac taatgctctt ggtccagatg ttttaacttt tactatttgc ttatcagtta
    27661 caccaaattt agcagcatct tcattgctca tatgtatatg tctagaagca actataactc
    27721 cttctttcat ttcaacttct ccagcaggtc ctactaattt aacacctgga gttccagcta
    27781 tatcaccaga ttcttttatt ggtgctttta ctcctaatgg gaaaccatct gctaaagata
    27841 tttcaacttg agtatgagct ctagctggtc ctagtactct aactcccttt aaagttcctt
    27901 ttggtcctac taaatccact ttttcttcac aggcatattg ccctggttga gataatggtt
    27961 taaatttagt taactcatga cccgccccaa ataatacgtc tatatcagct tgactcaaat
    28021 gaacatgttt attagataat gctattggta atttcattga aattccctcc ttttaattat
    28081 ttaaattatt gcaatacaat tatacataat attacctaca aaatcaaatt atattgaatc
    28141 aatatatatc tttaaatttt tatatattat atctttaaat tcttgattat ctatataaga
    28201 tacatcatct gtattgttta aatatatatt gtgtaaaagt ttagtattta tactcttaaa
    28261 gaaaaaatcc ataacaatct gtccaccttt aaactgtgaa tcatatgatt tactcccccc
    28321 cactgcaata tacattccta tccgtttctt atttctatca attgaaggtt tatttaatac
    28381 atatttactt gcatatatag cttgagttct atcaacaaca gtctttaatt tagctgatat
    28441 tgaatcaaaa tgtacaggac ttattactat agttcctttt gaatcatcaa acattttata
    28501 taatggcttc atatcatcat taaacttgca ataccctgtt ttttcacaaa atccacatgc
    28561 tgtgcaatat tcaatatcca tattgtagat attaaatatt ttacaactta acccacactc
    28621 ttctagcata gcttttactt tatttgctat aaaactgcaa tttttattaa ttcttggact
    28681 tccatttatt attataatct ctgtactttt aagtcctttt ttatcgtttg aatccataat
    28741 caatctacct atcctttaac ataactatta aaatatcatc atcataatta tcttttgatg
    28801 agaaattctt taaatccaat tttagatttt ctactattaa ctgttgattt aatctaaaat
    28861 tttcttttag aaagttttct aatctgttta taccatactc ttcttttgat gaatttttta
    28921 tctctaaaat tccatcagtg tacatacata ccattgcata atcttccatt gaaagagtat
    28981 tattttcata agtagcatct ttcattattc caataggtat gcccttttta caatttaaat
    29041 tattttctat tgtgccatct ttctttacaa ctacaggact atagtgacct gcattagaca
    29101 cagtaatcat attttcttta gtatctataa tacctatcaa acaagttgta aatactccca
    29161 tcttgtcaaa ttcatcatat aacatcctat ttaaatttgt cattatttct cttggtgtat
    29221 tgtattgatt gcataatact ttaaaagcac cttttatcat tgcaacaaca taatttgata
    29281 ccattccatg tcccattaca tcagcaacaa tataaactat atgttcgtca tccacttttg
    29341 tagcataata aaaatctcca cctactaccc ttgctggttt atggtaaaaa taaagttctt
    29401 tctcatcatt acaatccatt ttacctttat ccataataag ctgttgttgt ttatttaata
    29461 tgttcaactc attttcaaga actttgtgtt ttacttcctt ttcattatgt tcatataatt
    29521 gcatcccaac agaaacttgt ttggacaata tactaagaat atttaaatca tcactagtat
    29581 agtttttact atttgcacaa actatacatc ctatagtctc atttttatcc tgaagtttgt
    29641 aatatatata actttccaaa tttatgccct tttttgagca tggttttaaa ttatttaggt
    29701 atccccctaa tgactctttc tttaaaaaca tatcaatcat aggatataaa tttgttttct
    29761 ttttttgctc aacattataa caactaacta tagtatcctt attatgatga ctatttataa
    29821 ttattaaagc ttctttacta ttagtaatat tacacgcttg tttacttaaa ttttccaaaa
    29881 agccatcaat actcttatta aggtatagtt ttttagtagc ttcatttatg gcacttattg
    29941 agcctcttag tttatcaatt aaaatttgta cattattatt tttattagtt atttctattg
    30001 ataaacttaa gagtgatgca acagatgata taaaatctat atcttgttct gttatataat
    30061 catcctcttt taaaaaacaa gtcataaatc caacaactac attatttatt ataaaaggaa
    30121 aaactattct cccaatataa ccttcagctt ttgctaaatc tcgttcacct tctgctctag
    30181 aatcttcaaa tacattttcc acatatatta tctttttttc atttacagcc tcatgtatat
    30241 actctggata tgtgtcaaaa tcaatttttg cacctttaag actatttatt ggaaaaattt
    30301 gaggtacata ttctaaggtt tgcgaacata ctaagtaggc atatttagaa tcatttttat
    30361 aaaatagatt tacacatgcc tttgtagggt gaacaacttc taacattttt tctattatgt
    30421 catcttttat attaaaaaaa tctgtagatt ccgtcaccat agcggatatc tccactaaat
    30481 tcttcatttt ataactgcca ttagtcatac tcaatttctc cccctatata ttaaactatt
    30541 tattagtatt ttaacataca ttctttatag taaaaacaaa aacaacgaca aaactagcaa
    30601 ctaatatcca gttaaatcct gtcaataatc ctataagaag taatgtaatc aatgcattta
    30661 gacctgttct ccctttttca tccataaaag ttattttaga gatgtcgata ttatttttca
    30721 cattatttat atgctctttt acttgttctt ccatatttct tttatatagt atataaacta
    30781 caccaattaa aaacactcct atacctagaa tcatgtttaa attaaaagct atcataagca
    30841 gtattgaacc aaaagccaac tttaaaagct taaaaaatac gctatctatc tttagagtta
    30901 tatttctgat ttctttacat tcatctctta aagaatatcc acttgagtct aggttattaa
    30961 tctttgtttt tacaatttca gaataaaaaa gctttattat cccatttaac attttcatca
    31021 ctcctaaata ttttacatat atttgtaagt tttacaatta taatattttt tatacttggt
    31081 aataataaaa aataacaaat attttatgat ttagtattta ctgtaaataa attattgaag
    31141 ctttattagt taagtataga tttttaataa atatttttat aattagaagg aagtggtttt
    31201 gtgcaaatag aacaactcga tttagaaacg agaaataaaa tatactgcta tactaaaaaa
    31261 attcttagaa aatatcaaaa aggcataaca tctggaaaat taacagcaga taaatttgca
    31321 gataatatat tgtctcaaca ttttatcagt agtatactta atgaaaaaat agtcaatgag
    31381 acaaatttta agatatctta tagaaactat atagaaactt taataaatat tcaaaatgaa
    31441 aatttatcta acttaagaaa aaaatctact aaaactgcaa aatgtttcaa tatctctcaa
    31501 ataacccaat taaaaaactt actaagtaat actggttata atttattaat tccatataaa
    31561 tacttaactg ctagagatat agaaggaatc gttactctta ttaatactgg gtctattgaa
    31621 cttggaaatg agagaatcta taattatata tcaaaagcat aataatttaa acctattata
    31681 aaaaggcaat ttatttaata aaaaatattt ttaatattaa ataaattgcc tttttaattt
    31741 tggactaaat actgctatcc aagtgctttt tctagtttag ataaatgttg tattggataa
    31801 tattttagta gctctttaaa ttgttctact gataaacctt ctgttgttgt atatattctt
    31861 attttttcat ctaagtcact attaataaat ttgtttttta aatcctcaaa atttacacta
    31921 ctcattttac atcactcctt atgtaacata ttcatttgta ttattttatc caaatacata
    31981 aaatttatta cataaaaata tatctattta ataatttaat aaaaaaaagc tatctcaatt
    32041 tagaaattac tttctatatt tgagatagct ctagctaaac taatagccaa tagttataaa
    32101 taattattta taactatctg ttgctttttc cagccatttg ttgttcagcc atttcaacta
    32161 attttttagt catgtatcca cctacataac cattttctct tgcagtaagg tttcctttat
    32221 caacttgttg ataattactc ataccaagtt cattagctat ttctaatttc atttggttta
    32281 aagcctcttt tgctcctggt actactgttc tgttgttgtt attgttactt gccatgttga
    32341 ttaccttcct tctgtttaat ttattttgtg ttgctgataa tattatgtga ttttaaacat
    32401 ttttaattca ggtaattttt agcaattaaa acctgccaaa tatccagtag aaaaagctat
    32461 ttgcaaattg aatccacctg tatatgcatc tatatctatt acttctccag caaaaaataa
    32521 accttctact aattttgatt ccattgtgct tgaatttatt tcgtttactt ttacaccacc
    32581 agaagttatt atagcttctt caataggtct gtatctcttt actgtaaact ttaaattttt
    32641 taataaatgg actaagtttt ttctctgctc tctagaaatt tggtgaacaa ccgtatttgc
    32701 attaatttca cttaagttta ttattatagg tattagtttt tttggaagta aatcatctaa
    32761 tgctttttca aattttttat ttgtatactt ctgaaaatct ttttgaactc ttttatccag
    32821 tttttcctca tctaatgcag gttttaaatc taataatata gtgtaatttt ctttccttgt
    32881 atctttcatt ctacaacttg cagacttgat tataggtcca tctaaaccaa atctagtaaa
    32941 ttcaagttct ccaaaatcac tataaacttt cttttgtttg ctattaaaca cccttatttc
    33001 aacatttctc aatgataatt tttctaaatc ttttgtaaaa ctttcttgta cttctatacc
    33061 aattaaagat ggttttgtat ctataattgt gtgcccctgt gaaattgcaa atttatatcc
    33121 atcaccagta gaaccagtaa gtggataact taatccacca gttgctacta caactgaatc
    33181 acacttaatt tcttttttat cgtttaaaat tactttctca attttattat ttttagatat
    33241 tattttttct acttttgaat ttaataatat atttactttc ttacttttaa gttgtctttc
    33301 aagagcattt acaatatcaa aggctttatc actctctgga aaaacccttt ttcctctttc
    33361 tgttttagtc tttactccaa gattattaaa catacttatt acatcatcat ttgtaaaagt
    33421 ataaaaagca ctataaagaa attttccatt tgtaggtaca ttttctatta attcctctat
    33481 ttcacaagcg ttagtaatat tacatctacc ttttcctgtt attgcaagtt tttttcctaa
    33541 tttatgattt ttctcaatta atgttacatc atagcctttc tcacatgcag ttgatgcggc
    33601 tatcatccct gctggtccac cacctattat tactaccttc ttcaaataat cactcttttc
    33661 tacccttaat ttttttaatt taaactattg actctatacc ttaaaatcaa tttaatttta
    33721 aaagtttaaa taatgctgga gctcctgcta ttccataaaa aacaactact gtattcttaa
    33781 taaaattcat aaaaattata ctcatagtag agtcacttat atttaaagtg actattaaca
    33841 ttgaaataaa caacttaatg ccaatatata acattcctat tgttactatc ccaaccaaaa
    33901 acctacatat tcttgaaaaa attatatttt tactcccctt atttttattg ctaaaattta
    33961 tttttttgtt attattatct gtattaaatt taacaaatct atcctcaacc atatatccaa
    34021 atacaaatcc tactattata ccaaattttt caaaatattc agggctattt agaaatatag
    34081 ctactattat aaatggtata agtaaaacta caagtaaaat ataattttta ttatcatcaa
    34141 tatagtcaaa tatttttata aatataactg taaaaaatat tcctaacatc caacccacta
    34201 tcacatctat tggccaatga acagctaaat acagcctaga caatcctact cctaaaacca
    34261 taactgcacc tattaaatga agatatctct ttttaaatat agtcataata ctaacccaaa
    34321 atgttgttgc agtttgagta tgagcacttg gaaaagaata accaccagca gtagaaactc
    34381 tcaatgattc aagacctttt attcctattg gtctgggagc ttttacaaac tctttgatgc
    34441 ctaaatttac aacaaaattt ccaattatag caaacagtat tttctgtcca cattttttat
    34501 ttatacacca gtatataatt gttgtaatta atattaataa cggtgcttct gtgcttattg
    34561 taaagacaag aaatataaag ttcaaaattg gatttcttaa attttggaaa aataataata
    34621 tatttaactg aatatccata tagatgtctc ctttactaaa attttatata attaactaaa
    34681 aagcactaac tcccttagaa attagtgctt ttgattcaca tttaaatcta ttctacatcc
    34741 tcaactatac ctatataagg taaatttcta tacttttcag catagtctat tccataacca
    34801 acaataaatt tgtcttctat aacaaatcca acatagtcta caggtatatt agcttttctt
    34861 ctctgaggtt tgtcaagtag agtacatagt tttaaagatt ttggatttct agtttttaaa
    34921 gctgcaacta gattacttaa tgttaaacca gaatctatta tatcctctac aatcaacaca
    34981 ttctttcctt caatatctac atctaaatct tttaatattt taactgttcc agaagactct
    35041 gttgagtttc cataacttgt aacactcata aaatctatat ttacatccaa atctatacat
    35101 cttattaaat ctgaaacaaa tacactagct cctttaagta tacctaccac tagtaaatct
    35161 tcgcctttaa agtcttcttc tatctttttt cctaattcat aaactttttc ttttatttgt
    35221 tcttctgtca acatttttcc tgtaactttg tacattttgt atcctcccgc tttccttcta
    35281 ttaacttata tattatagca taccaaaata tcaattaaaa tctttttcat catttttaga
    35341 cctaaattaa cagcttatcc atactttttt gctttttcca ttaaaaattt ggaataacga
    35401 ttcctttgta ttataatcta tatgtacata tattaatcag ttatttttat cgattatata
    35461 attttatttt tggaggtact tttatgagca caaatcatgg agctaattta tatagtttat
    35521 ctagtaagta tggcttttca aaggaagaat ttatggattt tagctcaaat ataaatcctt
    35581 ttggtacatc aagtttagcc aaacaataca ttgtaaacaa tatagatatg gtatctatgt
    35641 atcctgaccc tgattacata gacttaaaaa cttctatatc caattactgc aaatgttcta
    35701 tagataatat agtacttggc agtggagcta cagaactaat ttcatcattt atacatacaa
    35761 ttaatcctaa acaggctctt ttactctctc cagcctattc agagtatgaa aaagagttat
    35821 ctaaaattaa ttgttctata gaaaaatact ttgcaaaaga agaagataat tttcatataa
    35881 atttagaaaa tcttataaaa actatcaatg ctaaagatta tgatttggta gtaatctgta
    35941 atcctagtaa tccaactgga tttgcattta ctaaagtaga agtgagagaa attttaaaaa
    36001 atacagactc atttttaatg attgatgaga cttatgtaga gtttactgat acagatacat
    36061 actcttgtac tcaattagtt gatgattatt ctaatttatt cgttataaga ggtacatcaa
    36121 aatttttttc aacgcctgga ataaggcttg gatatggtct tatatctaac actaatgtca
    36181 aaaatgaaat aaataaaaat ctagatttat ggaatataaa cataatagct tctaaaatgg
    36241 gggaaatcat gtttagtgat ttagatttta tatcaaatac tatttcctta atgaacactg
    36301 aaagagatta cctgcttaaa gagcttaaga atataaaaag cttagatata tacaatacta
    36361 aaggtaattt catattgtgt aaaatcaaaa caaaggaatt aactgctaaa tcgcttcgag
    36421 aacaactgct tccacaaaaa ataataataa gagattgttg ttcatttgaa ggtctagatg
    36481 agtatttctt tagagtatgt atattaaaac ctaatgaaaa taaattatta atatcatctc
    36541 ttaaagcaat ttttaaataa aaaaatccct ttattttata atttttttat accataaaaa
    36601 atgagctatc tctatttgag ataactcatt tttgattatt aaaaaactaa gcactttgct
    36661 cttctttgtt tcctttttta ctcattccat catttatttt atctactact actgctattg
    36721 cattatctcc tgatacatta catgctgtac caaaactgtc ttgagttaag tataaagcta
    36781 tcattaaact tgcaagccca ccatctgatg gtattccaac cattggtagg aaaggaagtg
    36841 cactcattat agccccacct ggtgctcctg gtgctgcaac cattgctata cctaacattg
    36901 caatataagg gaataataca cctattccat gtggcatacc attcatcatt aaaactgcag
    36961 ttgtaaatcc tgttattgat atcatactac ctgataaatg tattgttgca caaagaggta
    37021 caacaaattc tcttatttgc ttacttactc catttttttc tgcacaacca acattaactg
    37081 gtatagttgc tgctgaagat tgagttccta tagctgttaa atatccaggt acttgatttt
    37141 ttaacattct tactggattt tttcctgaaa atacacctgc tgctgtgaat tgacatgcca
    37201 tatatacaaa atgtaaaggt attactacta agtatacttt ccagaatacc cctaatattg
    37261 tccatacttc ccctgctata gttatatttg caaaagttcc tgctatgtat aaaggtaata
    37321 aaggtataat cactgttgac aacgttttcg ttacgattcc ttgaaattct tggaagaaat
    37381 taaataaagt ctctcctttt ccatgatttc ttaaagctga tattccaagt cccattacaa
    37441 atgcaaatac gattgcagct gttacatcta ccataggctc taatggaatt gtgaatattg
    37501 gagctaacat tcctgcctct gggtctccaa tttgacttgc aacacttgca tcaataaaat
    37561 ttgggaagat taatgtagat actgcaaatg ataataatcc tgctattaag gtagaaccat
    37621 atgctattcc cgtagttatc cccaataact ttcctgcacc tgttgctaaa tcagctatac
    37681 ctgctgttac aaaacctata attataaatg gtataacaaa ttttaggaat gctgagaata
    37741 aggtactaac tgttactaat atttgtacta ttatttctgg tgcataactt ccgattaaaa
    37801 taccgactat gataccgatg attagtttgg gcactaaacc tatttttttc ttcataatat
    37861 ttaccctcca taactttttt aaattaagca ttcttgcaca ttgaatactt agttaaatat
    37921 tggatatcca cttattatga taatagagtt ttacctctcc gtcaacaatt taaccatttt
    37981 ttgttaataa aaaaaagaat aacatatata aattgttatt cttcttcatc ttttatagaa
    38041 aattctacat tttcaattat atttgaatgt ttatcttttt ttataataac tctatactta
    38101 ttaatttctt cattcactat acctatactc caaattaaaa ctatagcatc atctataaaa
    38161 ccaaatgccc ctgcaatcat ctctggaatt atatcaaccc cagatacaaa gtaggatata
    38221 gtaaaaatta atacagaaat tacctttatt ttatcaacta tattgattct tttatctgtc
    38281 ataaaatcag gtagtttaag taaatcaaat acaaaaacca aaccaaattt agcattttta
    38341 aatctgacca aaattttttt taaaatatct aaaactatat taatgattat ttttaaaaac
    38401 tccatattta tcacctctta taattatagg ttattctaca ttataaccga tataattaat
    38461 ttgatgaaca tattagatat aaattttatc aattagttta tatttaaatt ataataattc
    38521 aattcctgca ctactacaat tttgaatcat atcctgtggc catactccaa cttgtacttc
    38581 tcctatatga gctttttgta agaaatacat acatattctt gactgaccaa ttcctccacc
    38641 aattgtatac ggaagttcgc catttaaaag catcttatga tagtcaaact cttttctctc
    38701 ttcacatcca gcaagtttca attgtctatc aagagattct tcatcaactc taattcccat
    38761 tgaagataat tctaatgctg aatctaaaac aggattgtaa aataatatat ccccattcaa
    38821 ttcccaatca tcataatcag ggcttcttcc atcatgtttt tctcctgata ttaatgtttt
    38881 tcctatttga gttataaata ctgctttctt ctcttttaca attttatctt ctctttcctt
    38941 cggtgataat tctggataca tatcttctaa ctcttgtgat gttataaaag ttatttcttc
    39001 tggtaatatt tcttttatac cttcatacat actacataca aaaatttcag tatctttaaa
    39061 tactccatac aatcttttta caacatcttt tagagtcttt tcatttctac tacttttatc
    39121 tataaccaat tcccaatccc attggtctac ataaagagaa tgtatattgt ctaattcttc
    39181 attttttctt attgcattca tatctgtata taaaccacta ccaacttcaa acccatattt
    39241 tttaagggct aatcttttcc attttgcaag tgattgaaca atttctgcat ttttattcat
    39301 aaatggtata tcaaagctta cagccttttc tccatttaaa ttatcatttg cacctgtttc
    39361 tggcaataca aataacggag aagaaactct tataagattt aattcattac ttagtctcat
    39421 ttcaaaaaaa tcttttaatt tttttatagc tatttgtgta tcaattacgt tcaaactact
    39481 tttataatcc tttggtatta ttgtgctcat atcattcact ccctatattt atatattttt
    39541 ccattaaaaa aacccttcat ccctatataa aagggacgaa aggttgcttt tccgcggtac
    39601 caccctgatt agtttgaaat aaattcaaac ccagctcaca atgtacagat attactcgat
    39661 acaccccaat atgataacgg tttggttccg actaagccta ctcttttaaa atttcggtta
    39721 gcaactccag gatgttcttc attatagact tcatattggt ctcacaccat caccaactcg
    39781 ctttaattac attctataac tactcttcct ttcaaagtct ttaagagttt aattcaataa
    39841 aatttagctc tcttatgttt tctatttatt cataatagta tgataagtga ttagttaaaa
    39901 tttgtcaagt ttattatttt tttattttta aacactttat aaatttttac ctatacttta
    39961 taaattttca aatatagtct ttaatctgtc catacattct tttaataaag actgtggaca
    40021 agctacattt attctttcaa atcctattcc ttcttttcca aatatataac cttcatcaaa
    40081 taatacatta gcttttttaa acattaaatc ctcaagttct acttcattta atccataagc
    40141 agtaaaatct aaccatgcta gatatgttcc ttctggataa acaagtttta cttttggtag
    40201 gttttctttt aagtattcat caataaattg tatattatta tctaagtaat catttaattc
    40261 attaagccag tcttcacttt cattatatgc tgctattgta gctacaatag caaagggatt
    40321 tggtgaagtt gcaactccaa cagctgtaac ctcttcttga tatttctttt ttagttcatc
    40381 attattcact attatattag acaactgcat tcctgccaga ttaaatgttt tacttggagc
    40441 tatacatgta attattttat ccttgtactc tgggcataat gactgtaaag gagtatgttt
    40501 aaatcctttt ctaactaaat cagaatgtat ctcatcagct attatccata ggtcatattt
    40561 tttacatatt tctacaacct tctttaattc atcttctctc caaactcttc caacagggtt
    40621 gtgaggacta caaagtatca gtactttatt gttgctacac ttagcttttt cttctaaatc
    40681 atcataatcc atcctataag taccattctc atatattaga ggattgttta caatgtccct
    40741 attattgctc tttatcttag cttcaaatgg gtaatacact ggtttttgga ctattacacc
    40801 ttcattagaa ttagttaata ttcttactaa aatagcaaca gcaggtacaa caccaggact
    40861 aaaaataata tcttttctat ttatttccca gttaaatctc cttttatacc aatcacaaac
    40921 tgcattaaag tatttatcac tatcatttga actatatcca aatattttat gttcaacttt
    40981 tttacgtaat gcttctatta ttggttctgc acattcaaaa tccatatcag caatccaaaa
    41041 aggcaaacca tctttttgtg cttttgttga acaattagtt ctaaaatccc attttacaca
    41101 atctgttcct actctatcta ttactctgtc aaaattatac ttactcattt tttccctcct
    41161 aagaataaaa tttttataat tgttaagtcc attactagat gcactttggt attattttac
    41221 aattcttaat attataataa tatcactttt ttgtccaata gatttaaaat ataattactt
    41281 ttccatcata ttttttcaat attccaaaat cagtttcatt atatcaaaat aagattgctc
    41341 atattaatta ttttctaatt aacataagca atctttttct ataacttcta taattataat
    41401 tttaaatgta gaattattag tttggatatt atcccaatct cttttcaacc aatctacacc
    41461 atatatctac accatattct aaagctttcg tatcaaatgt tacatttgga ttatgaaatc
    41521 ctggtgtagc atcagctcct aatccaatat atgtagtttt acattttagt ttttgtgtat
    41581 aataatggaa atcttctcca ccagaatttt taaatatacc tatagatgca tcagctccca
    41641 atacatcttt tatagtttct tcagccaagt ttacaagttc ttcatcaaat tctgctgctg
    41701 gtactccatc tttggaaatt agtacagctt ctgcatttat agaacttaca gcagttttta
    41761 cagcatgtat tgctttttct tttaattctt ctattatatc attactttct gcccttatat
    41821 ctaaagccat aaatgcttca tctggtatat tattataagt ttctccctta actgatatat
    41881 ttgttacttt tatagaattt ggtatagctg gatttactct tattgcattt attgcattca
    41941 ctgctaaaca gacagcatct actgcattta ctcctaaatg tggtttagaa ccatgacaag
    42001 tgataccttt aatcgtaaat tgcattatac agctagcaca atggtacatt gcaggtatcg
    42061 cctttcccaa cctacaatct tgtccaggtc ttaaatgcat ccctaccatt tcttctacat
    42121 catccaacaa accagaatca attactctta atgctccata taatttttct tcacctggtt
    42181 gaaaaagtat ttttaactta cctcttttta ctaaatttct ctcttttatt aactttgcag
    42241 ctgttaaaag catagaagta tgaccatcat gaccacaagc atgtatcatt ttcttttctc
    42301 catctatgat aaattccaat gcatccatat ctgctcttat agcaaatact ggtccttctt
    42361 ttttagaatc tatagttact ataataccag ttcctgcaac tcctttatta atattttcaa
    42421 accccatttt ttcaagctct tttaaaacaa actctgatgt cttatattct tcaaatcctt
    42481 tttctggtat agtgtgtaga taatcataca ctttatgtac atactcaata taatctttgt
    42541 tagttcccat aatctagctc ctccttaaaa tttaaacttt ccatttatat taaattttta
    42601 ttataattac ctatactacg aaataattca ttataagcat tgcaatacaa ccatttaaag
    42661 ttgctataac aaacatatgt ggataatatt tagtttttaa ctcagctgtt cccaaaagtc
    42721 tccccataaa ttgtatctgc gctcctgaaa gcaataacat tggcaataga attgcaacat
    42781 gtgcttgact tatttgacct gctgtaaata aacctgcgat tactccagat gctcctccca
    42841 ttgatataaa tattgtcatt atagctgttg ctgcaacacc tggaagtcca aagatactca
    42901 ttacaggtgt aaatattgtc cctattacat ccaaaagacc tgttaaattg aacacagaaa
    42961 ttatagcaaa accgaagatg acatttggag ccattgaatt tgtacttatt tggaatccat
    43021 ttctagctcc tccaataaac gcatctatca catttccttt tttaactttt acttcttttt
    43081 ttgctacctc actcatgtta agcttccccc ttgtcaaatt tatttaaata taatctaagt
    43141 aagttcgccc caacaaactt cataattaat attaaagcaa gtggtataaa tattggtaca
    43201 tctcctataa atggaaatag tgctgctcca gaagcaaaga aattcgtaat tgcagacgca
    43261 cctgaaaatt gaaatgcaca aaatacagct ttttgttttt catctatata cccatcatct
    43321 ttaagttctt tagtcataga tgcagctgca tctgtagact gtaaactagc tatcaaagtt
    43381 agtcctgcaa atccaggtaa ccctaataat ggctttaata gtggactaag aagcttttga
    43441 gctgccttca ttccatctaa gtggtctata actctaacta ctccaagtgc aaacataact
    43501 gatggtatta atgtcaatgc atatagccat ccatctcgag ggccagtacc tccatcacct
    43561 ctaaagtttg aagctaatgt acctacacca tcattaattg ttcccaatgt tccaaaagaa
    43621 cctaatacat tgttaaaatc caatactttt aatggtcctg gtgcatcttt aaatattcct
    43681 gaaaaaaata atgctcccaa tattaatgct acatacccat accattttac ctcaactttt
    43741 tctgttgttg attctaattt actcatataa attctccctc ctgtttaaat gaattttatt
    43801 agtatacttg tttaataagc aaaacttatg ccaatacctt aatgataaag cctttgtatt
    43861 tattttttta ttgtaaattt attccagcga ttaaatagct tataattact tacttttcaa
    43921 gtttaaaaat ataatatttt tttattaact atttaaaata tacattacaa tataaaaagc
    43981 tattttcctt atcttgcaaa aataatttta aaataggttt ttataggata aaatcctaaa
    44041 aaaacctatt atttaatcaa atatataaat ttatactact atttgttgta taatataact
    44101 taccttatac tttaaatact ttaaaaataa atactatttt gttaggagaa ataaaatgga
    44161 taaaaagaag ttaatcctta taacatatga taaattaaat agtgaccact acaaagaaga
    44221 attaacaaac ttttttggag acgaaataat catagaaaca caaaatatac ttgatggaat
    44281 aaaagaaaat ttagagggag aggtagtgct ttctctatca cctttaacta gtaatttttt
    44341 aataaaacat tttaaggaag atattgaaat tattcatgga acgaaagcac tttcaaaact
    44401 tggatatgaa aaaatgatga aactacctcc aggtacaaaa tcgttactta tgacaaccaa
    44461 taaaacttca gcatttgaga tggctactta tctatataaa attggtataa atcatataga
    44521 ttttgtaccg acatatccag attgtgatga aatatatgat ttagatacag ctataacacc
    44581 aggtcagatt agatttatac caaaatacat aaaaaatatt gttgatttag gttggagaaa
    44641 aatctcatta gatacatata tgtcattatt agtagtatta aaactaaaaa atgagaaatt
    44701 tatagaaaaa ctatacaaat tgtccaagga gacactaagt catgatttct taaatacgtc
    44761 attagataat atatctaaat taaaaactat actttacatg accattgatg aaataggtga
    44821 tggtctaata tttttcaaca cctttaacaa ggttactttt gtaaataagt ctttacttaa
    44881 tatgttggaa ctagatgaaa aacttataaa atcaccttcc ttaatggaat atatgccaaa
    44941 gagtttctta gataaaatta caaagaactt aaatatcgat aatatgatta tatacataga
    45001 cgaaatagat aaaaaattca tactttctaa aaaaccattt tatctttata aaaatataga
    45061 gggttgctta attacattaa aagatgtaaa caatatagaa atattagaac aaaaaataag
    45121 aagtgattct gtcaaaagag gttatgtagc taaatataaa tttaataata ttattggaaa
    45181 tagttctatt ataaaagatt gtattaaaag ggcaaaaaaa atggctctta cagataatcc
    45241 tatattaata acaggtgaaa caggaacagg taaagaagcc tttactcagt caatacacaa
    45301 tcattcaaat agaaaaaata aaccttttgt agcaataaat tgtgcttcat taccaagtga
    45361 attacttgaa agtgaactat ttggatatga agatggttct tttactggag caaaaaaagg
    45421 tggaaaaaaa ggattattcg aattagctca tactggcact atatttttag atgagatagg
    45481 agatatgcca catgatttac aggttaaact tttaagagtc ttacaagaaa aagaaattag
    45541 aaaaattggt ggtacaagta ttattccaat tgatgtgaga atattagctg ccacaaataa
    45601 agatttagaa aaattaatta tagaaaataa atttaggatg gatttatttt ataggataag
    45661 tatgttcact ttagatttac ctcctcttag aaagagatta gaagatatac ctcttctttt
    45721 agaatcattt ttaaaagaac ttccctataa aaacataaaa ctcgataaga gtcttttaga
    45781 agctttaaat tcatacactt ggatggggaa tattagagaa ctgagaaatt gtgttgaata
    45841 tatggcttac atgggttcca attatcttac aataaatgat ttacctcaaa acatatcttc
    45901 aaaattaaat aataatcata tgtcaagtaa tatgtctata ttcaatgatt taaaccaata
    45961 tgacaaaaac atatgcattt ctatcctaaa atcattgcac atgaaaccaa tggggaggac
    46021 aaagttaatg aaatttatgg aatataatgt cacagaatac gaagtaagaa atatgctaga
    46081 atatttgaca cgcaatggat acttaatttc tagtaaagga agaaaaggct catcaataac
    46141 tgagaaaggc ataaaaataa tagaaaataa tataatttaa acctatagta attcatcttt
    46201 actttatcaa aatttatata taattataat tttttatttt tctataaatt ttttataaaa
    46261 taataaaact tatttatatt aaaaaagaag ctatctcaac atagggataa gcttcttttt
    46321 aattgttaaa aagataaaaa tatatttgat ttaacagaaa aatagtgcct cataaactaa
    46381 aaagttcatt ttgagacact tccttaatat taataaatta attggcttaa aattactgat
    46441 tgataattat aaagtacctc tgttaaagga gtaaattctg aaccgattcc aaatcttaat
    46501 tctgtaaacg cctctaaata atctgggtca catacatctt cttgtgttaa atcttgtttc
    46561 accatttcag tagcaagata aattgctact gatggtagaa aagcatccat tggcatagga
    46621 tatccaccaa gtctatttga cataccaaaa gccttagcct tttcacttat catgtcgttt
    46681 attttatcat aattttgagc atctttttca gatattttta gacccataac actaggatac
    46741 gtttgtattg gtgatggatt gctttgctct gcaactatat actttaattc taaagcctta
    46801 gtcaatataa cttcatccat atactcattt acaccaaata catttatatc ttttccatat
    46861 tttttaactt gtttttcaat atcttcattt aaaaactgct taactttgtt tttgtcttct
    46921 tcagtattta tatttggagt attaacttgt acaaatggca atcctatatt tttacaagtc
    46981 tctttaatca tttctaatct tttggctata ttaacatctt tcaaatcatc tgtagaggca
    47041 taatgaataa aagcttttgc tcccatttct tttgaacgtt cagctaatac ttttcctctt
    47101 tcctctgcac taacccctag attcacatca acaaattggc ttaattggtt tttatcatct
    47161 cccatagggg cagaaatagt tattatttct ggacgctttt cctttacctt ttgtaaagca
    47221 ggtaaaagcc ctgcttggtc agttgaaact acaatagcct gaacttcttt atcgtcagcc
    47281 aactttacta tcttattaat agcactatct atattagaag taaaattctc tggcaataca
    47341 acatgtttta tagtttgttt aactttagtt tgaccatctt tgtctttatc aattttattc
    47401 tcttcctcat attcttttgt catctcttcc accatattgt attgtacttt attttcagat
    47461 aatggttgag ttaccactgc aactttaaaa tcatctataa ttttctcttt atctttcttg
    47521 cctacaagta aactacaacc tgtaagtcca ataattaaac atatggatag cataaatgct
    47581 gttatttttc taagcattaa ttaaaacctc ctaaatttgt actttcttat cactattact
    47641 aattttatca tacttcaaag aaaaattata ttataaaaaa ttatatacat gctattccaa
    47701 tccaatctaa aaagtactat gggtagatta ggtttagatt aaacctaccc atagtactaa
    47761 aaattaatat attataaaat taaattaatt acaaattatt atgctacttg tttgttgctt
    47821 tttataaagt taccaactat tccacccaat atagctggta ttacccagtt aaagcccaaa
    47881 cctgcgagtg gcaagctttg tataaatgga acagctcctg tcattccatt tatagctgat
    47941 aatagactaa tcactaatgt aacatatgct gcacctttaa aagcattatc attctttata
    48001 tgtttaccag ccaactccat aacaactatt gctaataaaa caggatatat agtttgtagg
    48061 attggaactg atatagctat tatagaatca acacctaaat ttgatataag catactagct
    48121 acacatatac ctataaccag ttgtttataa ctcgccttac ttattccttc aaaataagtt
    48181 gatattgatg ctgttaaacc tgtagaagta gtcagacagg caagtgccac aattacacct
    48241 aaaattacct ttcctacttg accatataac aatatactag ttatttcaac taataaagat
    48301 gcttgaggta tactagtatc atataaagtt gaaactgttg cacctaaata agtaagacca
    48361 ccatatacta ctgctagaaa tacacaggct acaaaaccag ctttaatagt cattcctatt
    48421 tggtctttat ctgatgtata tcctttagct attatagaca tcaacattat agttgccata
    48481 gatgctgcac ctagagcgtc cattgtttga taaccttgtg atataccttc accaaataga
    48541 tttttatcta tcatatgctc aggactcata ggtcctgctg gagaaattat accctttact
    48601 attaaaacaa ataatactaa taataacgct ggagttaaat acttacctat tatgtctata
    48661 accttagaag acctaatagt aaatgctaaa gttaacccaa agaagattat tgaaaatata
    48721 gctttagcta ctggtccatg gtctccaaat ataggcataa tacccatttc atatgttgtt
    48781 gcacaagttc ttggtattac aagaagtgct aaacatgcta gagcagctac actcattact
    48841 cttgctaacc ctttaccagc tctcctaagt acatcatcca tgcttccctt gcatcttgct
    48901 gttgctataa taacaagcat tgctatacca gcatctgcaa caacaaatcc aataagagga
    48961 attaaccagt ctttgccgga ttccatccct aaaaatggag gaaacataag atttcctgca
    49021 ccaaagaaca tagaaaataa agcaaaacca actataaaaa tatctctcat ctgcttactc
    49081 acactaaatt accccctttg aaaatatttt gaatattaag ataatcttac tttattttca
    49141 gaaaaatgtc aatctggtaa aaattcacac attgttaacg ttttcccaat ttattttatg
    49201 aatatttttt tcattttatg ataattccca tcaatttcgt taaatcaatt gcttgtgaca
    49261 catcaaaaat tgctcctcta atctcatcta taccaatctc aattccctca atattattag
    49321 tggtaaaatc tatgccagaa agtttagttc cattaaagtt tgcttttttt aagtttgtat
    49381 actcaaatac tagattgtca ccttttactt cttgaaatac agaattttca aaatttgaat
    49441 ctaagataga aactatctta aatttagaga atgaaaagtt agaatactta cctaaaacat
    49501 ccttgaacaa aacgttttta agtatacaat catcaaatct aactcctatc aatttactat
    49561 ttttaaattc aactctgtat atacttcctc catcaaaaaa tgaatttgat aaattgcagt
    49621 tttcaaatac cacatcaagt aaatcaatct tttttaaatt gcaattttca aaggatacat
    49681 ttctaaatat acaagattca aagctaactc ttacagaatc taaatcactt ataacttcat
    49741 tttctataat tttattaaat attttttcat cattaaatat atcttcaagt atatcttcaa
    49801 gattttcaat aatttctaat tctcctgtaa atttaggttt ttgcacttta ataattttag
    49861 tcattttccc ctccactata aattatatta tttttgatat tatttttttt aatatattaa
    49921 cttaatatac atatttgata tattaaaaag tttttacgaa atatccgtgt attcagtact
    49981 tttataatta tatcacaaac tcatttataa tagacttcta tataatagta taaaacaagt
    50041 tagaataatt gacattatac ttatacatat tcaattattg aaaacagtaa ttcttgccaa
    50101 taaataacct taatttttta taaaatcgac aaaaaaacga ataattttat tatatttatt
    50161 gtaaataata caatattacg atataataca acagaaaaac aaatagaaaa tgttcatata
    50221 atattagtaa tacggtctaa tagtttctac aaactcacct taaatgggtt ttctatgaat
    50281 agaatatcaa ctttgaatat atgttctatt ctatctatat gaatatatat ttttttgttt
    50341 atatcttaaa gttttttgga ggtaaaaatg gtaccaaaca ctaacaatgt acaaccagat
    50401 ggaaataatt catcattaag ctttttagac aaaatgttta aatttagcga acgtggctct
    50461 agccttaaaa cagaagtaat aggtggagtt actacattct taacaatggc atacatagtt
    50521 ttcgtaaatc cagcaatatt atctgaagct ggaatggata aagccgccct tataacagtt
    50581 accatactag ctacagccat tggtacactt atatttgcga ttttaggaaa tgcaccattt
    50641 gctctagctc ctggtatggg attaaatgca tttttcacat actctttggt tataggtgca
    50701 ggaatcccat ggcaaacagg tcttggggta gtttttctat ctggatgtgt cttctttaca
    50761 ctcgcagtaa caggtcttcg aaagacaatt gcagacgcaa ttcctagaga attggcagta
    50821 gcatcttcag caggtatagg tcttttcctt gcttttgttg gtttaaaaaa tatgggtgtt
    50881 ataatagcta atccagatac tatagtttca cttgcagatt ttacaccaac agttttaata
    50941 gctctttttg ctcttatctt aatggcaata ctagaatata aaaaagttaa aggtggaata
    51001 ttgataagta tagtagttgc aacaataata tctgttatat ttggatttgt ggagttgcca
    51061 acagcaataa tctcaacacc tcctagtata gcaccagttg cttttaaatt agatattgta
    51121 ggtgcattga aattctcatt aattggacct atattctctt tcatgtttat agacatgttt
    51181 gattcattag catttcttat tacttgttgt aaacaaatgg gtcttgaaga tgagaatggt
    51241 gaaataaaag atttaggaag aatgttatat gcagatgttt cttctacttt aataggctca
    51301 ttcttaggaa ctagtactgt tacaacattt ggagaatctg cttctggtat cgcagcaggt
    51361 gcaagaacag gacttgcttc aatagtaaca gcagcattat tcttagctac acttatattt
    51421 acaccattgc ttggtatagt tcctacttac gctgcagctc ctgcacttgt aatggttggt
    51481 gtattcatgt ttgaaagcat aaaacagatt gattttgctg atagcaaaat agctgtacct
    51541 gcttttgtta cagttttatt gatgccttta acttatagta taagtattgg tttatgcttt
    51601 ggatttattt catatataat aatgcatgtg gtagctaaag aaactgataa aatcagtatt
    51661 acactttgga ttataggttt acttgcagtt gtaaacttag ttctaagtta atattttaaa
    51721 tagttctagg tcaatatttt aaatttataa atagcaaaat caatttatgt ataaattgat
    51781 tttgctatta actttgtata gaaaatttat tatcataata catagatata aaaatatata
    51841 gaaaagaggt tgtacttatg tcacaattac ttataaaaaa tgcatatcta attactatga
    51901 atgcagatag agaggtatat gaaactggaa gtatacttat tgaaaataat attataaaaa
    51961 atgttggtaa gtttgatatt aatattgtag ataaagatgc tgagatatat gatgctaaag
    52021 gaaaaatact aatgccaggg ttagtcaata cacacgttca cttatcccaa caattaggac
    52081 gtggtcttgc agatgatgtt gtacttttaa cttggcttag agagagaatc tggccatacg
    52141 aaagtagctt caactatgaa gattcattga tttcatctac tgcatgttgt gttgaattga
    52201 taaaatctgg ggtaactaca tttttagaat ctggtggtca atatgtagat gctatggttg
    52261 aagctgttga taaaactgga cttagagcct gtttagctaa atcagttatg gatacaggag
    52321 atggtcttcc tgaagcatgg caaaaaacta ctgatgagga aatcaacact caattagact
    52381 tattccataa gtttaataac acatctaatg agaggattaa aatatggttt gcattaagaa
    52441 ctatttttaa tacaactgaa gaattgctta ttaggactaa agagttagct gataaataca
    52501 atacaggtat acatatgcat attgctgaaa tagctgatga aatttcattt gtaaagcaaa
    52561 acaacggagt tggaacagtt gaatatcttg ataaactagg tgtattagga ccaaatcttt
    52621 tagctgctca cacagtttgg cttactcata aagaaattga tttatttaga ttacatgatg
    52681 taaaagtttc tcataatcca ggtgcagcta tgaaagtagt tctaggattt gcctcaattc
    52741 ctgaaatgtt agaaaaagga atacctgttt caattggtac tgatggagct ccttcaaata
    52801 atagaatgga ccttatgagg gatatgtatc ttacatcact aatacataaa ggtagaactt
    52861 taaacccaac tgtcgtacca gctgaagaag tcttagaaat ggctactata aatggagcaa
    52921 aatgtgcttt actagaaaaa gaaattggta gtcttgaagt aggaaaaaaa gctgatatga
    52981 ttattctaaa tccagataca attcattgtt taccaatgca taatccaatt ggaaatatag
    53041 tttattctat gactagtgaa aatgtagatt ctactatttg tgatggtaaa tggttgatga
    53101 aggaaagaaa agtattagtt gtagatgaat ctgaattatt aaataaagtt aaaaaacaag
    53161 cttctaaaat aaaagataaa gcagaagtta aaattccatc taaatttaaa atcataaaat
    53221 aacataaatt tcaattgttt tgtaaatatg aatatataaa tatatttata cacatcatat
    53281 atacaaaaca attgtttttt tattttatat tcattaacat tgctcataaa atacaccata
    53341 attccagaaa aaataaccaa tcagttagga ttacatcatc taagcaatat ataaacgtct
    53401 tagtttataa gttttattct actcttatct aaaaccatct ttaaagagtt ttcaactgtt
    53461 tcaattacat ctttataact caagtacaca tttgcgtaga tacaatcttc atataaatta
    53521 tattcagtta ctctacaata cagcagtttt cctccatcta ataaattgct caaaatatag
    53581 ttttcttttc ttgggacata gcctattaca tatccagttt caccaactat tttaatagct
    53641 ttttcatcat atagattatc tttctctcta gttaaatagt atatcttact cttctccaat
    53701 tctttttcaa gatattctct atttctaaac cttgaaccag caacagctat tgaagtcaaa
    53761 tagatatcct taccatgttc atctactttt attttttcaa tatttacaaa ttcttttttt
    53821 aaattattac tttcatataa tactcttctt aattcatcct tcaatataac atttttttct
    53881 ttttcatacg cttctttaac aatttttaat tcttcaagag atagtttctc tctgtatctt
    53941 tttaagatat ttatggattc ttttcttact tcatttatat ttccaaatat tccttttaaa
    54001 gatatattct ttccttcagg atatagtgat ttacttcctt taagcacaat aaaaaataac
    54061 atatcatcat aatattcttg agtcaattta tctttttcta tatctttcat ttttccaatt
    54121 aaatcatcta ttttaaacgt ctcttcaaaa aaatttaata attttaatct agaacttgtc
    54181 gttccctttt tagatatatg ccaatatacc tcaaaatctc taatatctct attcagatat
    54241 ggcaacaagt catcaaaaga taagtttaca tcataaattt ctgacatttt tataatatct
    54301 tctgtttttc cactagcatc tcttaatgct tcaaaatata tatttttcca tttttcactg
    54361 agcaagatat catttatttc tttttcaaat tcaatcttat tgtactctat attttcatct
    54421 tttaagacgt ttatagctat taggaaaatt gaatataaac tttcaaagtt agtcccataa
    54481 tttactacag taggtaaaaa tcgattcact aattctaatt tattacctat atatttaaat
    54541 tctacactta gcaagtaatt gcatataaga cgtgctaaat tatttatctt ttctttatct
    54601 aaatctcgtt tttcaagata ttcattcaaa tctacaattg aaataatata gttcatcaat
    54661 aatcgttcgt actttgtatc cttataacca tcttcaatta gataggaatt tattttagaa
    54721 tctaaatttt ccatattaac aatagcaaat acttttattg aacctgtagc ctttttagat
    54781 aaattaaata aatatgtatt gtaaaattca agttttttaa tagtattact cagataaaat
    54841 acgtattctc cagatttaga aaatgtatct acaacttctc ttaagttttc tacatttaga
    54901 tatttctcac ttaaaactaa ccctagtttt acatactcaa cttttttact cttatatatt
    54961 aattctttag ttaatttata taaccatttc tcatcaataa tcatttcttt taccaaagta
    55021 tttatctttt tcataaaaat ttcgaaataa caaattaaag acttagaatt actatcctcc
    55081 aataaataaa tttcattaga ttcactttta tacatattta aaatttcatc tactagatta
    55141 tttgcaagtt ctacttgttc tcttaacggt atactttcat atatacatag gtaattcatt
    55201 tcaaatgatt ctttgtatcc atcataacca ttaaattcct gcaatcgctt aaaaacattc
    55261 tccaccaaat tatcctcctt tacatgatgt aatttatatt gattatacta cttatttcgt
    55321 caagtttaca tttatacgca aaaaaatatt actagaaatt gaaattctag taatatcctt
    55381 attattaatt atgtaaatac cctatcttat aactgtaaat aatatcctta ttaattttaa
    55441 ttacttttaa taaaaatcta tcctagattt agacttctct atgcatatat tatactaata
    55501 ttagacatca taatcataca ctttttcttt ttcatatctc atgtttacaa acaatgcaag
    55561 taaaattcca acaaatgtta ttgccacatt aaacaataca acatattttg gtccattaac
    55621 tccccctgat tttgtaataa tacctgctat atttaaaata acatagtttg ctatactaga
    55681 tgcaatcata actatagatg ttatttttcc tttattagtt ggaaacattt catttgcagt
    55741 tgacgttgtt aactgaagaa cacctcctgc tgctgaataa cctattacaa atccccctaa
    55801 catacaaata gttggagttt gaacaaaata tacaattaat agcataagta aagctattat
    55861 aggatatata actaatattc ttattggttt aatatatttt ttaataagta aagaagttat
    55921 taatactgca catattactc ccattgagta aaaggattga atttttgtag ggtcagccat
    55981 cccatacaat ttacccaatt cctgattaca atttaaccat aatacaaatg tagatgtaca
    56041 tgtaaatcca atacaaacaa gagctatact tgttggtgta aatttcatct tctctgattt
    56101 aactgttttg cctttgttat caataacatt attagctggt ggaaatggta acacagctat
    56161 caaaatggca tctactacaa taagaatcgc tgttactata aaaataactt taaatgatat
    56221 tgaatttgct gcaacaaatc caattataaa aggaagcaaa aattgtgcta aagctattgt
    56281 aaatttagta aacatatttg ctattgttcc taaactagca aatatctcca tacaagaagg
    56341 agttacacag gtatctaaga atgaatttgc tgcccctcca attattgcaa atacatatgc
    56401 tatataaaaa tttggtgaaa atacaattcc aacaaagaaa attgcatgta gaaagtttcc
    56461 tataagacca cttacttttc ttccatactt atctgaaata ggtcctgcaa atggataaga
    56521 tataagtctc cctaatccta gtgcagcaat aacagctaaa acaatactta catccaatgt
    56581 tccatctgat agtgttttag ccccccacat tgatgaaaat tctggtttgt attgtcctaa
    56641 aattgaaatt ccaataccaa gtaaaaaata tgaaaaatac aacgctatgg cagtaggata
    56701 atatttttta ttgttcataa tttttctccc attcttgtta atttattaac atttttgtgt
    56761 acaataaact catcctcata atggatttaa agtatagtca gttaaagctt caaatttaac
    56821 tggactatga tgcaaaaccc actatgacaa tttgtaattt attattaaaa atattgaaat
    56881 acgtatgttt tttcattgtt taagatatca ctcttatcta tttaaagcat aattcattaa
    56941 cttcttctac aggcatttct aatccagtat atagattaaa agcttctgct ccttggtata
    57001 ataacattcc taatccacca atagccttac atccattagc ttcagcatct tcaatcattt
    57061 ttgttttctt aggattataa acgacatctg ttactactaa gtcttttctt aaaacactag
    57121 tatcttttat atttgtttca ttgtcataag gcttcatacc aataagagtt gcatttgtca
    57181 atatatcact tgattctatc tcctcataaa gtttgtttgt atcttctaaa tcatatagat
    57241 taacaacaca ttctggtaca tcttttttta tattctcaac tgtctgctct gctcttttat
    57301 aaaaatcatc cttagcatta aagatagata tttctcttgc tccatctaaa gcacattgta
    57361 cttgtatagc agttgctgca ccaccagcac ccataattgt aatcttttta cctttaactt
    57421 ctatcccatt ttcttttaaa ttacgaacat agcctactcc atctgttata tgaccaacta
    57481 actttccatt gtcatttaca attgtattac atgctccaat tatacgagct gctggagaaa
    57541 gttcatccat atattctgta acagcagatt tacatggcat agtaacattg gctcctttta
    57601 tattaaaagt ttttattgct aaaagtgcct cttttacctt atctactgtg atatcaaagg
    57661 ctaaatatct ataatctaaa tctaatttct taaaactata attatacatc actggtgatt
    57721 tagagtgacc aactggtgta cctattaatg caaataatcc tgttctacct gaaatttcca
    57781 taactataat ttcctcccaa tattatcatt ttctttgcaa ataacctatt cagttattta
    57841 caaagaaaaa tttatttatt atttatatat ttaatgctac ttcaaaagct tcttttgttg
    57901 catctaatgc cctacgagct tttactgcat caccaacaat ataagtttct tttacaactt
    57961 cttttataac ttcacttaat gggtcgtaat tacgagaacc catagcaagt actactgaat
    58021 caaaaccttt taaatcatgc tctgtgccat ctgtaagtaa atagtcgaca ccatcatcat
    58081 aaaatttaga aacttttgca ccagtaatgg tatgtatatt ataattttca aaatcattca
    58141 taaggaattt acggtgttct gaaattacat ctgcaccaac ttcttctcta agctcaataa
    58201 cagtaacctc atgttcttgt tctccaagga aggctgccac ttcacatcca accattccac
    58261 ctccaacaac aagtactttt ttcccacaag attttttacc atcaagaagg tctacagcat
    58321 gaattaatcc tgaatcattg attcctggta taggaagtac aagtggagtt gctccagtag
    58381 ctataataac tacatcaggt gatttctcct ttataagttc tactgtagct tctgtattag
    58441 tacatatttt tacaccatat tgattacatt ttgaaatata acttctaact aagttagtaa
    58501 tatctccttt ccctggagga tatgcagcta aacgcatttg cccaccaaga acttcagatt
    58561 tttcaactaa agttacatta tgtcctcttt tagcacatac ccatgctgca agcatacctc
    58621 caacacctcc accaacaaca agaacttctt tgctaatttc agctggctta agctctgctt
    58681 catgtcctaa tataggattt gcaagacagg ctataggttt tccttggaac atatttggta
    58741 cacatccttg taagcatgca atacatggta tcatttcgtc tagttttcca tttttagctt
    58801 tattaggcat ttctgggtca gccaagcttt gtctaccgaa tgctactaaa tcacatcttc
    58861 cttgtctgac cattaactca gcaaactgtg gctctgtata acgtccaact gttattactg
    58921 gtatactaac agcttttttt atttcagtaa ctaattctgc actgaatcca gcatgtaaag
    58981 tcgtaggagc ccacatatat tcatcatgta tatgtatact acgtgaaaca tgaagtccat
    59041 ctattccaca accttctaga tatgctgcta ttactgaact atcatgtata tcaattcctc
    59101 ctggaacatc atcagtgctg tttatacgac ataatattgc tagagaattt cctacttttt
    59161 tacgtatatt ttcaatgata agacgaggta atctcattct attttcaaaa catccaccaa
    59221 actcatctac acgcttattt gttctttgtg atataaaact actaaccaga tatccatgag
    59281 cgcagtgaac ttcaacagca tctgcaccag ctttttgtgc acgtaatgca gcatctccat
    59341 aagattctat aagttcatat atttcttctg ttgttattgc tagtggtgta ttacgaccat
    59401 ttgatgcagg tattgcagaa gcagctttta atggatgtcc tgctactttt tcatttcctt
    59461 cagaaccagc atgttgtaat tgtatagata ccttcgaacc tgcatcatga caagcatcta
    59521 ttacattttt aaaactatct attgtgctat catcatataa acaaggctta cgaggacctc
    59581 cttttgcttt tttgtctaca acactagatt ctatagttat taatccaaaa ccacctaaag
    59641 cacgctcaag ataataagcc ttagaagttt cacttaaagt accgtctgtg tttgcaaaat
    59701 tgtttcccat agggggaact acaaaacgat ttggaactgt cattgaacca attcttatag
    59761 gtgtaaacat agaactaatc ttcataaggt tttccttcct ttcaagtttt atatttaaaa
    59821 gttttatatt ataatactct gtatattttt atattatata agtttatttt ggagatactt
    59881 cagaccatgc tttatccaaa acttttttag ttgcattaaa tacagtttca gcagcagtgg
    59941 ataacccttt agatattaga gaatcagata ttacttctgc ccctatgact cttggtgata
    60001 tattgtgttc ttttattatt ttcacaaatt cctctgtgtt tccatatcct tcacctggag
    60061 ccaaacggtc atgtagtgat tcatccctaa gtttttcata aggagtttct aaaacatcac
    60121 acacttgaat tgatactatc ttatctgctg gaacaggtgc aaggtcctct gctgtctgct
    60181 ttgctctagc ccagtgccaa gtatctaata taagcattgc attttcacga ttacatcctt
    60241 tcacaacacg ccatgcagta gccaaatctg gtacaccact atatggcata aactcaagac
    60301 ctataataag ttcacctgct ctgtcacata attctcccaa tgcagttata atttgttctt
    60361 ctggtatcat ctctaataat ccacaattta tatgtttaac attaaataag tgagccatat
    60421 gataaacatt ttgctctttt tctctttgag cttcagttct atcttcttct gttccccatt
    60481 gagttatata ttctacttct gtaactttca tatcatattc attaagaatt gcaatcattt
    60541 cttcatctgt aacacctgca ttttttgcat caatataatt ttcagcacgc aatccaatac
    60601 catcaaatcc agcttctttt gcaatacgaa ctctatcacg gaatgaaact tctgttccca
    60661 atgtataaga actaattgta attggaatat taagattttt ttgattattc atagcttaaa
    60721 tttgccccct ttattttctt tataattaat agtatctttg attttatatt tttatttatc
    60781 ctactagtag tattatttta ccttaaaaat aaaagtattt tttgatttct atttatctag
    60841 attttataaa tttattgtat cacgagactt tactaataac aaattgataa tttcctatta
    60901 attcatagat tttgtttata gattttattt ataagataat tcttgtattt ttctattagg
    60961 ttgtataaat atatttatct tataattcag acaaaaaacg ataaattttt ttaaaagctt
    61021 ttattcttac tctataatca tatataataa aaatgtaaaa atatcttaaa ggttaacttc
    61081 tacaaatata taaataaaaa tacctatgaa aggatgaaca aaaattgaat ttatatcact
    61141 tacgctattt tgttacattg gcacatttag aacactatac aaaagcggca gaaaatttat
    61201 ctataacaca accaagctta agtcatgcta tttctttact agaaaatgaa cttggggtgg
    61261 ctctatttga aaaagaaggt agaaatatag tccttactaa gtatggaaaa atatttttaa
    61321 aagatgtgga aaaatcatta gaaattttag attcaagtgt aaaatcatta aaaataactg
    61381 gtactggtga aggacaaata gacttagctt ttcttagaac acttggtact gattttatcc
    61441 cagacatagt gcataaattt ttaaaatcta atcctgctaa atcaatagat tttaaatttc
    61501 atactggtgt aactactgac attattcaag gtcttaaaga aagaaaatat gatattgcat
    61561 tttgttcgaa acttgaaaaa gaaaagggaa ttgaatttat acctgttgcc aaacaagatt
    61621 tagtactaat tgtaccatat agtcatccac tagctgcaaa ggatactata gatttaaaag
    61681 aaaccatacc ttatcctcaa atagtattta atcagagaag tggtcttaga tatataattg
    61741 atgatatgtt taaaaaaata aatcaacagc ctaatatagt ctatgaagta gaggaagacc
    61801 aagtaattgc tggattagtt gcaaaaaatt tcggaattgc tgtagtccca aatatgaata
    61861 tgcttagctt tacaaaagta aaagtaattc agattattca cccaagttgg gaaagaaact
    61921 tttacttagc atttataaaa gatagatatt tgcctcctgc aattaaaaac tttaaaaact
    61981 ttgtcattaa aaacgctcaa ttataattta ttaataaagg ggttattttt aaatatcctc
    62041 ttttattctt tttataaaat aaaaaaatct atacttttaa aagtatagat tcctaactga
    62101 cagtcggcat ccgagtctca gtaattatcg ttatacaaca gcaactggat tcagttcctg
    62161 aataactagg ttatttacat tatatcagat ttttttaaat ttgtcaattg tatctaacgc
    62221 attttttcaa gccatggtcc aacaggctct acaataggaa cttctttaaa tccccaattt
    62281 cttatatcat tcacactcgt tggagtatat attttgtttc tgacagattt gaatattttg
    62341 tttttttctc catattgcat acactttgga ttagcttcta ttaaccctct tcttgctctg
    62401 ctaagaggat tacataaaat atctgctatt tctaaacctt ctctatagtc agcatcttct
    62461 tttttggcaa ttataaaacc cttaacctta tctcttaatt cttcatctat atctaagtat
    62521 attgttccat tattaaatac atcaaaaaac gccttttgta cttttaagtt tgagacatca
    62581 tcccttgact ctataactat tcgtgcagat tctacagttt cattatttac aaatgaataa
    62641 aaattctgaa gaacatgtat aaaagccaca acatacggtt cctttgaagg tgcataatat
    62701 ttctttaatc tagctttatc tactgttact gatattatag tacactctaa tctagataga
    62761 aataaaggca actcatcata gaataactta atctgtgaat catcaaactt ctcaaatgct
    62821 cttgattttc ttgatatatc tgtcaaatgt attcctatgt tactggttcc aaaacaatac
    62881 tctttaaatg catccatttc tttcctcaaa gaacatacat aatcgccttg acttactgca
    62941 tatttatatt caaaaattac tcctgtcaat gtaaatgggt cttcatgatt tatatcagct
    63001 cttccacttt catcaataaa cattatatat tttttcttta taatcttact caccctctta
    63061 acatatgatg atagcatcta tattcatttt atatgagttt taaaaatatt ccaagatttt
    63121 tatataactt aaacttaatt ttatactaaa aaattgagat gtaaaacaat caagctttta
    63181 ttgattgaat ttcacatctc aattataatt atttttcaat atatattttt actattttgc
    63241 aagaatatcc attaatttat ccattactat ataagatact ccgcctccta tttgataagg
    63301 agtttcaact tttttatttg caaatactct ttgttgctct aatgataatc ctgaattatc
    63361 cattaaaact attggtgaat gtaattttac agctaatggt ccagctgata aagcatctac
    63421 taaagcatct gatttactaa ctaatacagc ctgtaaatca gtatctccat agaatttttc
    63481 tattactttg gcattagtat ctactctact atctccatat attctatttc ctgaaatatc
    63541 ttcagtagtt atatcattca tttttgctat tactgaatcg ttaattgcac ttggtccacc
    63601 tataaagtat gcattttcta attttctttc tgttagccat ttataagatt cttctgtaat
    63661 tccatcttta ttgactaata ttataggttg tttttcttcc ccagctttag aagctacaga
    63721 taaagcatct gcttccccat ttccagaaac catatatgca gtttttattt cttctcgatt
    63781 tccaagttct tcagctattc ttgtagcagt ttgatatcta tcttgacctg ctattctctt
    63841 tgtctctgtg ttgaaagtag tttttatttc ttgctctaat ttagaactta ttgcattttc
    63901 tccacctatc aagattactg ttttaggtgc taataacttc atttcttcaa cagtttcagt
    63961 tggtaaatta gctgtattag taagtagtat tgttgagtca tagctacttg ctaaaggagt
    64021 tgctgttata ccatcagcta ttgcattacc atttactaat attacagtat ctgaactatc
    64081 agcattccag tttccaactg aacttatctt tttagctgta tcaaatctat ttgcacctat
    64141 aattgtatcc catgtaggat ttatagttcc atcttcatta aaagtataat ctttcccatc
    64201 tattttttga gaaccagtta gcatctttcc atctttgtct aaatagtaag acttaccatc
    64261 tatttgttgc catcctgtct gcattattcc tgttttgtca aagtaatact tattaccatc
    64321 tatttcttgc catcctgtta ctgataaacc atcagatcct agatagtatt tctttccatt
    64381 cttttcttgc catcctgttt gcattactcc atctgagtta aagtaataag tttttccgtc
    64441 tattactttc catccagata ctcttgctcc atcagttcct aaataatatt ttttgttatt
    64501 aattgctttc catcctgttt gcattactcc tgaagcatca aagtaataca tttttccatt
    64561 tacttttagc caactattct tttggtatgt tccatcagat tttacataat acttcttacc
    64621 attttctgtt ttccatcctg tttgatttag atttatctta tattttgccg ctatctttac
    64681 atagctgtca ttactataat ctataattac atctgaacct acaggaactt ggtcaaataa
    64741 ccatctaaca tctttattgt gcattcttat acatccacca gaaatatgct ttcctataga
    64801 actctcatta ttatttccat gtattccata tgtatctcca taagttcctt ttaatgctaa
    64861 tcccatccat ctatctccta atggatttct tggacttcct ccaggtatat tacctttata
    64921 atatggtcta ttttttatct tgttaactac ttttgttttc cctgttggtg tttctgaccc
    64981 ctttttacct gttgcaactc taaattcttt tacaagttta ttatttacaa aatatcctag
    65041 agtattcttt cttgaattta ctataatcac atgtttactg gctgcgcttg attctggtac
    65101 gccacatgca aatactaaaa ctaaagtcag tgctagtact aaatactttt ttagactttt
    65161 tttcactata acttccccct cttttagaaa cattactaca tgtgtctaat tataacataa
    65221 aattaccaat accttatatt tacaaatttg ttacatttat acatataagt atgtattcta
    65281 ctcttcatac ccattaggat tcatactttg ccatctccat gaatcttcac acatctcttc
    65341 aagttcatac ttagctttcc atccaagctc tttttctgcc tttgaagaat ctgcataaca
    65401 catggctaca tctccagccc ttcttcctac aatcttatat ggtatttctt ttccacttgc
    65461 tttagaaaat gcttttacta aatcaagaac actataaccc tttccagttc ctaaattata
    65521 aacaacaagt cctggatttt cttctaattt ttgtaatgct tttacatgac cagcagctaa
    65581 atctaataca tgtatatagt ctctaactcc agttccatca tgtgttggat aatcattacc
    65641 ataaacactc aattccttca atttacctac tgctattttt gttatataag gcattagatt
    65701 gctcggaact ccatttggtt cttcacctat tctaccactt ttatgagcac caactggatt
    65761 aaagtatctt aaaagagcta tatccaatga cttatctgct tttgatatat ctactaacat
    65821 ctgctctatc ataagtttag ttcttccata tggattggtt acagaaagtg ggaaatcctc
    65881 taatatagga caagtatgtg ggtctccata tacagtagct gaagaactaa atacaaactt
    65941 tttaacacca tattctctca ttaattcaaa taaatttaag gtacttatta gattattgct
    66001 gtaatattca attggttttt ctactgattc accaactgct tttaaagctg caaagtgtat
    66061 aattgattca atattatttt ctttaaatac aacatgcatt tcatctttat ttctgatatc
    66121 aatattataa aattttactg gttttttaga taattcctta attctatcaa ccactattga
    66181 gttgctatta cttaagttat caactataac aacttcataa cctgattcta aaagttctat
    66241 tgctgtatgg cttcctatat atcctgctcc tccagctact aaaactgcca ttgtaattac
    66301 ctcttttcta atattttatt tttcacttac tttttttctc atatagtcca ttaaatcatc
    66361 ttttaaattt tctctcttta gagcaaagtc tattgttgcc tctaaaaaac caatcttatc
    66421 tcccacatca tatcttctac cttcaaagtt ataagcataa atagcctctt gttttccaag
    66481 agtttgaagt gcatctgtca gttgtatctc tccaccttta ccaggtgtct gtttctctaa
    66541 tatactaaat attgcaggag ttattatata tcttccaagt atagctatat cagatggagc
    66601 ttcttcaatt gcaggttttt caaccatatc tttaacttta tatactctat cttcgatatg
    66661 ttttacatcc aatataccat atttattagt atcttcttta gctatctttt gaacacctaa
    66721 tacagttgtt ttatactcat tataagtatc tattaattgt tttaagcacg gaacatctga
    66781 atctactata tcatcaccta ataatacggc aaaaggttca tcacctataa aactttttgc
    66841 acagtaaatt gcatgtccaa gaccttttgg ctctttttgt cttatataat gaatatttac
    66901 catatttgat atgtctctta ccatttctaa catctctgtc ttaccttttt gctctagttc
    66961 taactctaat tcaactgatt tatcaaaatg atcttctata gattttttat ttctacctgt
    67021 tattataaga atttcttcaa ttcccgattc tatagcttct tctattatat actgtaaagt
    67081 tggtttatct actataggaa gcatttcttt gggctgtgat tttgttgctg gtaaaaatct
    67141 ggttcctagc cctgctgctg gtattattgc ttttttaact gtcatctgca ttttttcacc
    67201 cttcttcgta aattttctat tgtaccaaat taatatacca tatttatact ttttcttcaa
    67261 actctatatt atcccaatat ttaatgctat aagataatat aaggtagatg aaatttcatc
    67321 tacctttagt tttataagtt aatattgtat tgtttatatt ttatccaaaa cttatacagg
    67381 tactaaattt catctaagat gccttttata tcactatcta tatcttcatc tagataagaa
    67441 tctaaatctt ctaagtcaac ttctagttct tgatatgtca tatcaacact gacatcctca
    67501 tctatatcca tttctgatat taattctcct aaaatactat ttccatcaga atctaaacca
    67561 ctatctatat cttcatctat atagttttca tttaaaattt catctaaatc aatctcgtaa
    67621 taaacttcat tatttttttc atcccctgag tccaatccta agaactcata gttaaaagtc
    67681 caaacattgt atttacttga catactttat tcctcctgtg aaaaacatat tttcatctag
    67741 tttattggtt ccataatcaa cagagttata tattttttca attatgtctt ttcttctttc
    67801 ttttgtacta ttatttaatg tcaattgttt aaatacatat gtatttgtta ttctctcgaa
    67861 taatatttct tttatactat catcatcaat atttctatag tttttccaca ataactcaaa
    67921 taacttaaac atttccctac tagtttcatc tacataataa ggatacatat tttctactaa
    67981 atggtttaat cttgatatgg cttgttttaa aaatacatca agacttgcac tttcactttc
    68041 ttttaacatt ctataattgt atttcttctt atcttctcct gaaattacaa agatgatatt
    68101 gtctaaactt ttttcaactt catttaaata actgcttata ttatatgata agtcagacaa
    68161 tagattttta atctgcttaa acacttgtac atcaagttta gtattatact tttcaaacaa
    68221 atctatttct tgattttcta atattcttgg catatatgct gacaataaat ctaaattgtt
    68281 tctttgttct tgtatttgct tataaagtga atttataact tctattctta tttcatcatt
    68341 taactctttt tctaaaatct tatcaaattc agatttcata tagtaaatat ttccaaaaaa
    68401 attaaatatt atcatatcat tcatagcttt agaccaattc ttatatatca cttcaataga
    68461 attttcttta agtagaggtt gctttgcata tataaataca tcttgcataa gtttttgaac
    68521 catattttta cttaagttta aaagtacttt ttgattatta aattttattt ccgtttctac
    68581 aaaattagaa ttttcgtttt caagttcttt attaattaca atgtctttta tatcactatt
    68641 ttttatagat atgatttctt tttgaaaaga ctttagaata gtcaagctat cgaaatcttc
    68701 ttgaataaaa aatggagcat gttttaatgt atatcccact atttcatttt ctatatcttt
    68761 taagtcatct atttgcataa tttctctatt tttatcattt atatgtaggt taaatacatt
    68821 tttattatca tataatatta tatcttctcc taaatttaac ttagaacaat tatctttcgc
    68881 tgactttaca atagtcttct tagatttctt atttataaaa attaattggt cttgatattt
    68941 tactaaaagc atgtttgtgt ttttataatc aaatccatct atatttcctg atatcttgca
    69001 gaatactata tcacaatctt taggaagatt tcctattttt tggttatctt taactctctc
    69061 atttaaatca gatggaacta cactatctat attgttatta aatatagata cagaccttac
    69121 tataatcccc tctctttcca tatgaaagta tcccttcaat gacactcttt tatcttctaa
    69181 aatgtatctt tctatatcat caaaatttat ttcaaatcta tttttcccac tgataaatat
    69241 aaacttctca ttatctttat taattccacc catataaaac ttattgtcat ctaaacttaa
    69301 tatagtcata ttatccttta gatagaatat aaattctctt tgacttttgc agattaaatc
    69361 atattcatcc aaagttattt tcatagtcaa atttgctgta acatttttac ttgaattttc
    69421 actttttatg taaaaaggca agttatttcc atagacaatt atttgagaat cttctaaaac
    69481 tgcctctaat ttttctttat tgtctgaaaa actatatata tattttacac ctgtatcctc
    69541 attaacttca tctgatttgc tgattattat attccctaga tttgttatat gaagcttttt
    69601 atattctttt gagtatctac ttatgccact aagctcaaac ccatcagaaa gctcatatat
    69661 gattttttct cctaatttca acataccttc accacctaaa cagaattata agtattttat
    69721 aaaggtgaat aaaatgtctc aaaacaaata atattttttt aatacttttt attctgagac
    69781 atagtttctc cttttttata atgctctaag caccttcaac tatttcttca taaagtttat
    69841 ctaaatgttt aacatattca cgatatccag atttgttctt taactcactt cttaaatctt
    69901 catatttttg tttaagttct tcagcactca aagaaggagc tgattctttt aattcttcta
    69961 acttataatc atagtactta tcatacatag ctatatatgt atcaatagat ttcttagcta
    70021 gttcattaca tttttcttgt gcttctccat attgagaata atcacctatt tttattttat
    70081 agtatccatt ttcttgaatt attgttgaag aaataccttt agcctcatat tcttttgctg
    70141 tttcttttgc tgttttttca actttaagtg aacctgcata aacagtgtaa tatacacctt
    70201 taccatcttt atatgcttcc atttcttttg ctttcttttc agcttgtgct ttttcttgag
    70261 cctctttttc agcttttgcc ttttcttctg cttctttttt ctctttttca gcttgtgctt
    70321 ttttctcttc ctcagttaat ttattgttag cttgttgttg agttgatgac tttggaatat
    70381 tctctttatc atttttctta ttgttgccta ctgttataaa atatcctaca ccaacaataa
    70441 ccactataac tactgctata atagtttctt ttaatctact cttcttagaa acaacctctt
    70501 catcatctaa agaatcttct ttatctgata cataattttt catttctttc ttgttttctc
    70561 tatatttgtc cttagaagaa tttttagatt ttttattact attttctttc tttttaatag
    70621 gtattactac tgatttttca ttttctaatt tttcttcttt tatttctttt gcttttttat
    70681 cttctaagtt tttactttct ttttcaagct tcgattcatt atttgaagat actttttcat
    70741 ctaagttatt atttattggt ttttctattt ttacactacg ttcttcttct atatgttgac
    70801 ttggttcttc ttgttttatt tcttttaatt cattttgctc tatttcttct gattttgctt
    70861 gatgattttc aactggttta tctaaaatta tatcaggaga aatatcattt aaattctctt
    70921 cttcttgttc aacttcttca ttgtcttttt taataaatcc aaataattta gccttctttt
    70981 tactcttttt attttctggt tcaattatat cttctttatt gctgtcgtac tctttatctg
    71041 tagtatcttt atcttctaca acgtcaccta tatcttgatt attactatct acttcttctt
    71101 tagccccttc ttcagcatca tcttctattg aaatactact tctaaagcaa atatctttat
    71161 ctgcattttt tatcatgtaa atgtattctt caatatcgat atctttattt cttctagttc
    71221 tttttgatgc aatttcatga ttttctaatt cactatagtt atcttttatt agattctgtg
    71281 ctttattcca tgtatcttca ctaatttctg ttttattttt aattacatag tccacaaatt
    71341 ccttaaaatt ttcaggacca aattctccaa ttatagtcag tctcattgca ccttctataa
    71401 ggtctctatt tcttctcttt aaaaattcta atacaaccgt tgcacaagca aaatctttaa
    71461 taatttcttt gccaaaacca tatccttcaa cagaatgaag ttcttctaat ccacataact
    71521 tcttatattc attgtgtatt gtttgagata tactttcatt atttaagcta tttaacttat
    71581 ctataaactt cgattctata tcatttgatt ttgattcatg ttttactttt gaatttttaa
    71641 tttcatttag tagcatgtca ttttctgaat tatctttacc taattgcaaa tcctcaattt
    71701 cagttgcttt tatttctact ttgtcttgtt cgttattctc ttccacatta ttaggtacca
    71761 catctttatt gctagctaat attttgttta cacagaatat aatttctctt tttaattctc
    71821 ttttcgcatc tgcttgattt ttaagaaata aatctccaca ttctttcttt tctaaactta
    71881 tttttctaag agatatatta aggaggtctt tatataggtt taaaacctta taatcctttt
    71941 ctaaacgtct tcttctctct gatagttcca ttttatcata agctaaaaaa ctatttaaat
    72001 cattggcttt tagagagtct aatccctctt tcatagcctt atttacatac tttctacatt
    72061 ttgctgtagt taattctaaa tctttttcta attcatctat ttcaggtatg tacttatcta
    72121 ctatccattt gccaataagt ggttctgtat ttcttgctaa tgtcttataa aacaatatat
    72181 taaattttaa aagctctgca tattttgctt cattaaattc tactttttca aatttctttt
    72241 ccaaaacacc atctagcttt tcatttattt tagactcttg ttttaaaaaa cttgctgtga
    72301 catttaaaac agtgtttctt attatattat tttcactcaa aaccttcact ccttaaatca
    72361 attattttat tgtaatattt acattgtgca aagttgctaa tttgattatg atatctaaat
    72421 aattatttac taaatttgct acatcttata tcatatcata ttatttacat cattttactt
    72481 tttcttttta tatctatctt atattatacc atttttaata tctgtactaa cttatattac
    72541 aatattcctc aaaattttaa aagtagatta gacaaattta caaataaaaa aacatcagtt
    72601 taaactgatg tttttgacta tcgaaataat taagcaagtc tataagcgga gttctgtatt
    72661 agataatcat ctttctaggc ctattgtcac caataggctc aagcgaccta cctaccggag
    72721 agtacgagca gcactcttta ttcctatctt ggtcttgctc caggtggggt ttacatagcc
    72781 aactagtcgc ctagctgctg gtgagctctt acctcgcctt tccatcctta ccacaatagt
    72841 ggcggtttat ttctgttgca ctatccttag gatcgctccc actaggcgtt acctagcacc
    72901 ctgctctatg gagctccgac tttcctcatg taagattaca tgcgattatc tggcttactt
    72961 aatatttatt ttacttagtt atgttaacac aaattctttt acatgtcaaa gtaatattat
    73021 actaaaaatt taaatttatt caaaaatagt gtaatataga tatataaact ccatttaact
    73081 cgaggtgata tattgaaaaa attatataga atagtaatta acattatact agtattagta
    73141 atactttaca gtggatttaa tatatactca aaacttacca aatacaatca tgatactaaa
    73201 acatcctcag aacttcaaaa aaaagaatat aaaaaagagg atttatcaaa gattaacagt
    73261 gattttaaat tttggctttc tgttgagaat acaaatataa attatccagt tgtacaatct
    73321 aaagataatt cttactatct tgacaaagat ttttataaaa aagattctat ttctggtaca
    73381 ctgtttatgg attatagaaa taaatctatt gatgacaaaa atatcataat atatggacat
    73441 aatatgaaaa ataaaactat gttcaacaac ctaaataagt ttaaagatgc tgacttcttt
    73501 aaaaacaata ataaaataaa aataaccttg aatggaaaag aatttttata tgatgttttt
    73561 tctgcttata ttgtagaatc tgattatgat tatctaaaaa caaattttaa caatgaatct
    73621 gattatcaaa attacataaa tgatattact tctaaatcat tgtataaatc tcctattaag
    73681 gtaaatagca atgataaaat agttacactt tctacatgta cctatgaatt tgatgatgcc
    73741 agaatggtga ttcatggtag attgatttaa aactcacaga cacagtttaa aacaataatt
    73801 ttaaactgtg tcatctttta tacctataat ttataaatta ggccactaaa agtatgtaat
    73861 acaaaataac aaatacatca aacaataaaa aacaataaaa aaagactatg ctaaaaacat
    73921 agtcttta
//
LOCUS       DAEQJM010000016        59890 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.016, whole genome shotgun sequence.
ACCESSION   DAEQJM010000016 DAEQJM010000000
VERSION     DAEQJM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59890
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.016"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            52..861
                     /locus_tag="KRQ43_001324"
     CDS             52..861
                     /locus_tag="KRQ43_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2741687.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            1006..1245
                     /locus_tag="KRQ43_001325"
     CDS             1006..1245
                     /locus_tag="KRQ43_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741688.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1433..1609)
                     /locus_tag="KRQ43_001326"
     CDS             complement(1433..1609)
                     /locus_tag="KRQ43_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741689.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1663..1759)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2114..2788)
                     /locus_tag="KRQ43_001327"
     CDS             complement(2114..2788)
                     /locus_tag="KRQ43_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH2741690.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(3008..3562)
                     /locus_tag="KRQ43_001328"
     CDS             complement(3008..3562)
                     /locus_tag="KRQ43_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH2741691.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            complement(3640..4005)
                     /locus_tag="KRQ43_001329"
     CDS             complement(3640..4005)
                     /locus_tag="KRQ43_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741692.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4470..5255
                     /locus_tag="KRQ43_001330"
     CDS             4470..5255
                     /locus_tag="KRQ43_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2741693.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFDIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKEHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5626..6804)
                     /locus_tag="KRQ43_001331"
     CDS             complement(5626..6804)
                     /locus_tag="KRQ43_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBH2741694.1"
                     /translation="MKTNKISFNKGLYYLNTNANFNFQLNRIIMWDGGRLEDIQKVSS
                     KIVDSESWKTELMYLAQEAEQDGRTENAIAYYRMSEFFMYDGDPDKISVYKKATTLFY
                     NYYSEYFSNGTVQIFHVPYENITLPVMYAKAQGEVKDVILLHGGNDSYFEEFFFPMLY
                     LASQGFDIYLFEGPGQGGVMRLQGKHFTYQWERPVKTILDYFHLENITIVGASLGGFL
                     APRAAAFEKRIERVVAWSVFPNFLDIIVGSQPIKMQNLLRLLLKLKTKWLVNFIIKQK
                     MKSGDSMVVWGLKHGMYAYEASTPYEYFQKIKYYQIDSIAKNINQDILILGATQDHFI
                     DYRTVGKEIDLLNNVRSLTFRLMTEAEQASNHCNCGNSKLVLDTISNWIMMMKIHDRV
                     "
     gene            complement(6907..7671)
                     /locus_tag="KRQ43_001332"
     CDS             complement(6907..7671)
                     /locus_tag="KRQ43_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2741695.1"
                     /translation="MTTICVMIDHIFLDTEYRQPTIHKHLAKHIIISQSGNLSVTFDK
                     GESLQCKGIIIDSNVSHTVSSKDNKMLVFLIDDTSILAQNISQHQLLNHSFFVIDNLI
                     VERIQNIYTACQVKGLSQSYIDFSKQAFRLLNLNYHISSITDSRIQWALNHILKSTHI
                     HNEIFFEICAEVKLSKSRFSHLFKEQMGVSLNSYLALSKLRKAYELLLKSGDITSAAM
                     DAGFSSPSHFSASSKKYLGITASELIGKCKIYFIRQ"
     gene            complement(7860..8684)
                     /gene="pdaA"
                     /locus_tag="KRQ43_001333"
     CDS             complement(7860..8684)
                     /gene="pdaA"
                     /locus_tag="KRQ43_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH2741696.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            8905..12024
                     /locus_tag="KRQ43_001334"
     CDS             8905..12024
                     /locus_tag="KRQ43_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH2741697.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            12042..12641
                     /locus_tag="KRQ43_001335"
     CDS             12042..12641
                     /locus_tag="KRQ43_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HBH2741698.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(12898..15027)
                     /locus_tag="KRQ43_001336"
     CDS             complement(12898..15027)
                     /locus_tag="KRQ43_001336"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBH2741699.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            15293..15541
                     /locus_tag="KRQ43_001337"
     CDS             15293..15541
                     /locus_tag="KRQ43_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741700.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSTNKKQKSHSRDIKRKIS"
     gene            15707..17098
                     /locus_tag="KRQ43_001338"
     CDS             15707..17098
                     /locus_tag="KRQ43_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBH2741701.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKEDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            17213..18682
                     /locus_tag="KRQ43_001339"
     CDS             17213..18682
                     /locus_tag="KRQ43_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH2741702.1"
                     /translation="MSNVNKKLVIAIGAVALVAIIFIGIMCMQFKGEKIAKNTYVNGV
                     DIGKLTKSQAKQELAKKYKLENVEFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SSFFGNLSKTISTNFGKKSNLVVVINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLTNIDTNLGTY
                     STIFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            18747..19340
                     /locus_tag="KRQ43_001340"
     CDS             18747..19340
                     /locus_tag="KRQ43_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HBH2741703.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            19522..20868
                     /locus_tag="KRQ43_001341"
     CDS             19522..20868
                     /locus_tag="KRQ43_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH2741704.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIRKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            21050..21421
                     /locus_tag="KRQ43_001342"
     CDS             21050..21421
                     /locus_tag="KRQ43_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBH2741705.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            21414..22103
                     /locus_tag="KRQ43_001343"
     CDS             21414..22103
                     /locus_tag="KRQ43_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBH2741706.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            22623..23489
                     /locus_tag="KRQ43_001344"
     CDS             22623..23489
                     /locus_tag="KRQ43_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH2741707.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            23731..24540
                     /locus_tag="KRQ43_001345"
     CDS             23731..24540
                     /locus_tag="KRQ43_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741708.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKKGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGQGSYTFFVDEGT
                     AMEYIGEFKEDKKNGKGNFVFSNGNEYIGHFEEDMMNGIGNMLYNSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            24683..25747
                     /locus_tag="KRQ43_001346"
     CDS             24683..25747
                     /locus_tag="KRQ43_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH2741709.1"
                     /translation="MKRLIALVLVILIVLFYSPELIEEGYDLKEKFFQSEIWNEFLDK
                     ININNNSKKDKKEQNQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     KLYPDDREELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HINKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            25775..26494
                     /locus_tag="KRQ43_001347"
     CDS             25775..26494
                     /locus_tag="KRQ43_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH2741710.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKDLI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVKNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            26518..27102
                     /locus_tag="KRQ43_001348"
     CDS             26518..27102
                     /locus_tag="KRQ43_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HBH2741711.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGEAVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGYVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIIDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLENFITEARERVHM"
     gene            27104..28453
                     /gene="pabB"
                     /locus_tag="KRQ43_001349"
     CDS             27104..28453
                     /gene="pabB"
                     /locus_tag="KRQ43_001349"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HBH2741712.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDTHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            28443..29186
                     /locus_tag="KRQ43_001350"
     CDS             28443..29186
                     /locus_tag="KRQ43_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HBH2741713.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            29220..29921
                     /locus_tag="KRQ43_001351"
     CDS             29220..29921
                     /locus_tag="KRQ43_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741714.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISNIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELASKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            29947..30519
                     /gene="folE"
                     /locus_tag="KRQ43_001352"
     CDS             29947..30519
                     /gene="folE"
                     /locus_tag="KRQ43_001352"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBH2741715.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            30585..31376
                     /gene="folP"
                     /locus_tag="KRQ43_001353"
     CDS             30585..31376
                     /gene="folP"
                     /locus_tag="KRQ43_001353"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH2741716.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELEIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            31387..31752
                     /gene="folB"
                     /locus_tag="KRQ43_001354"
     CDS             31387..31752
                     /gene="folB"
                     /locus_tag="KRQ43_001354"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HBH2741717.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            31745..32251
                     /gene="folK"
                     /locus_tag="KRQ43_001355"
     CDS             31745..32251
                     /gene="folK"
                     /locus_tag="KRQ43_001355"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBH2741718.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDILFFN
                     DVASTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTVKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            32232..33017
                     /gene="aroF"
                     /locus_tag="KRQ43_001356"
     CDS             32232..33017
                     /gene="aroF"
                     /locus_tag="KRQ43_001356"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH2741719.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLKILKAVKDEVGMAVITELMDVRD
                     IDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            33272..35062
                     /locus_tag="KRQ43_001357"
     CDS             33272..35062
                     /locus_tag="KRQ43_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBH2741720.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLDCGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            35080..36246
                     /gene="rpoD"
                     /locus_tag="KRQ43_001358"
     CDS             35080..36246
                     /gene="rpoD"
                     /locus_tag="KRQ43_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBH2741721.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            36411..37100
                     /locus_tag="KRQ43_001359"
     CDS             36411..37100
                     /locus_tag="KRQ43_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH2741722.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            37114..38211
                     /locus_tag="KRQ43_001360"
     CDS             37114..38211
                     /locus_tag="KRQ43_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH2741723.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            38273..38845
                     /locus_tag="KRQ43_001361"
     CDS             38273..38845
                     /locus_tag="KRQ43_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH2741724.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEVLEEMNIEVDIFRVSDEVAKT
                     LPQYYLINYKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(38905..39372)
                     /locus_tag="KRQ43_001362"
     CDS             complement(38905..39372)
                     /locus_tag="KRQ43_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH2741725.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRI"
     gene            complement(39758..40234)
                     /locus_tag="KRQ43_001363"
     CDS             complement(39758..40234)
                     /locus_tag="KRQ43_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH2741726.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLRVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(40354..41445)
                     /locus_tag="KRQ43_001364"
     CDS             complement(40354..41445)
                     /locus_tag="KRQ43_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBH2741727.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDVDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNKLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(41438..41827)
                     /locus_tag="KRQ43_001365"
     CDS             complement(41438..41827)
                     /locus_tag="KRQ43_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2741728.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            42019..42465
                     /locus_tag="KRQ43_001366"
     CDS             42019..42465
                     /locus_tag="KRQ43_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741729.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEDIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            42729..43454
                     /locus_tag="KRQ43_001367"
     CDS             42729..43454
                     /locus_tag="KRQ43_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2741730.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCKYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            43441..44685
                     /locus_tag="KRQ43_001368"
     CDS             43441..44685
                     /locus_tag="KRQ43_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2741731.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMKNIDYGQKILSKYNYDKSIKINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFTSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGKGTEFHIIFHKMYDSD"
     gene            44765..45442
                     /locus_tag="KRQ43_001369"
     CDS             44765..45442
                     /locus_tag="KRQ43_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741732.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            45443..48004
                     /locus_tag="KRQ43_001370"
     CDS             45443..48004
                     /locus_tag="KRQ43_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741733.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDQNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIKKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGESYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAIEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGFGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNDFNFYDEISSSESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            48225..49499
                     /locus_tag="KRQ43_001371"
     CDS             48225..49499
                     /locus_tag="KRQ43_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH2741734.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(49660..52701)
                     /locus_tag="KRQ43_001372"
     CDS             complement(49660..52701)
                     /locus_tag="KRQ43_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBH2741735.1"
                     /translation="MFKQRISKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGNTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            52908..53207
                     /locus_tag="KRQ43_001373"
     CDS             52908..53207
                     /locus_tag="KRQ43_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBH2741736.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QDLINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(53445..55673)
                     /locus_tag="KRQ43_001374"
     CDS             complement(53445..55673)
                     /locus_tag="KRQ43_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBH2741737.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
     gene            55966..57741
                     /locus_tag="KRQ43_001375"
     CDS             55966..57741
                     /locus_tag="KRQ43_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741738.1"
                     /translation="MKYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLREKIGVVFQNSSVFGKSILENIVMGNEGISREDVIKSC
                     EIANANQFITKLENSYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
     gene            57754..59577
                     /locus_tag="KRQ43_001376"
     CDS             57754..59577
                     /locus_tag="KRQ43_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741739.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGVLASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            59695..>59890
                     /locus_tag="KRQ43_001377"
     CDS             59695..>59890
                     /locus_tag="KRQ43_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741740.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANF"
BASE COUNT        23691 a         6515 c         9842 g        19842 t
ORIGIN      
        1 ataatgttga tttaaaataa aaataggatt tcggaggagt ttattatata aatgaaagat
       61 tactataaaa taggagagat atctaaaata tatggaatag gtagagattc attaatgtat
      121 tatgaagaaa taggcattct aagaccagtt agagatataa atggatatag aatgtataat
      181 atatcagata tatggaaatt aaatttaata aaagaattta gaagcttgaa ctttccaatg
      241 aagaaaataa aagaatacct agatgacaga agtatagagt ctacgaaaaa tattttaaat
      301 gaagaactcg atttaattga taaaaaaata gctgaattta taagccataa ggaaaatatt
      361 ataaaaagat tgagttcgat tgaaagtgta attcaaaata caaaaataga tgagatagag
      421 gttgtatata tagaaaaaag aaaagcttta gaattaaatg ctgatataaa gagggatgaa
      481 gacttcgatt ttttaattca gaaacttcag aaagaatatg aagatagatt taatatactt
      541 ggaaacaaca atattggttc tgccttttct actgaagcaa ttaataaagg tatatttaat
      601 gagtttaaat ctgtattttg ttttctggaa agtaatgaga aagtatataa tatagttttt
      661 gatgaaggat attatgtaac tttaaattat actgggagta attctaataa taagatgtat
      721 atggagaagg tgtttaaatt tatagaagaa aataattata agataattgc tgaccctata
      781 gaaatctata agatagatat acatgagact ggaattgtag aagagtttgt aacggaaatt
      841 caagttccta taactaaata gccatatttc aatggattag atggtaaata gaatgaaaaa
      901 atgttgattt gccaccgatt tgctactgtg ttataaaatc ggtagcaaat tatattttaa
      961 attataagat agcatgaaaa aataattgtt tagggggtta taaatgtgaa atgttctaat
     1021 tgtggaagtg taaatattga aaagggtatt ttaacaactg gtggcatata tgctgaaact
     1081 attggattaa aatatagagg agatggaaaa ttagataaag ttataaataa aacttttcca
     1141 gtacaatcta ctatatattc agatttatgt ttagattgtg gcgaaatagt tagaacctat
     1201 ataaaggata atactgatag gaattggtgt aaagataaga aatagaataa tttttgaagt
     1261 atattaatat ttgaagttga attttattaa agatacaagt gaaaaagtat aaatgggaag
     1321 aaattgttat atggaagaaa actttgcata taggggagat tagtttttta atataataac
     1381 atttttaaat gtagataaaa ctaaaaaggg ttctctagaa aacaatttct atttaattat
     1441 acttacttac caataccatc acttgatgta aacaagattc tactacattt tctccgtact
     1501 ctagtataaa atcatctagc tgtgtatcta taaaatcaca ataatcatat aaactactaa
     1561 tataagcagt taacatgtgt gtacatttat ccatttcatc tctaaacata tatattacta
     1621 tccccctaaa aaactttcat aaaacaaaaa gaacaatatc tttttggcaa ctggctgaca
     1681 taactcatag tttattttat aagcgttagt ccctatagct ttgcgtcact aaatttctct
     1741 agttttgccg atttagtttt attctacaac taaaataata cactaggata agttattgtt
     1801 caacatactt gtcagaaaat tgaaatattt aacagtatct taacaatatg aaatctattt
     1861 ttcactcaag aaacaaacta tacatgtaga atatttaata aaaattatat ttagttttgt
     1921 attgaagttt ttgtattaaa aagtttagtt cacaagagtt acttggctag ataatagatg
     1981 agcaaaaata tcttgaaaaa atatatatga atggcaaaaa acaagggatg aattttatat
     2041 agactcatcc cgtaattatt tatatattga ccttgattaa atatattatt atttttaagc
     2101 ttcaattttt atattatatt tctaaagttt ctataagagg attatcgcta aataatttta
     2161 ataaatttgt ttttttatat cctttaggta acttagtata tataactact tctaaccaat
     2221 ccccatcaag gcgtttaata ttcatgttta taatttcaat attagatttt ttaaatttac
     2281 cttcaatata ttctatggaa tcagtgctgt tagaaatttt aagagaaact tgctctgctg
     2341 tagggagttt catccacttc ctatctctat gaagtgttat ctgtacaata acaataatga
     2401 tacttgaaac aataccaact aagtataatc cagagccaat ggcaagacct gtaccggctg
     2461 ttgcccatat accagcagct gtagtaagac cacttactga ttgatttcta ataaatatta
     2521 atccagcacc taaaaaacct ataccactga caacttgtgc tgcaacgcgg gctgggtcta
     2581 gaccaatacc tggagtaccc actatatcat taaatccata cttggaaaca atgattataa
     2641 gtgctgaagc taatgccact ataaaatgag tgcgtattcc agcttctttt agtctattct
     2701 ttctctcata tccaattaaa gccccacaga aaccagcagt aatgattctt gctatatatt
     2761 caaattgaat caatatatga tggttcattt atctagcacc cccttctata taatattata
     2821 tatactataa tactacattt tttatgtgaa tatagtaaag tttaaaattt atataatagt
     2881 tatatatgaa tataaaatgt ataaacgtat attatgtata taaaaatgat agaaagcatc
     2941 taattttaaa tgattaaaga gcaagcttaa ataaatcaaa cttgctcttt taacatagtg
     3001 tatgttttta tttgtgatag ttagataaaa atttatctgt gttttttaca tctgcaaaac
     3061 tgttctgtag tgatgccatg aatacttgat gtacagtatt tgcattaatt tctatattat
     3121 tccaagataa attcttcgtt gtacatgcat cgcttattag agttatgtcg tatcgaagtt
     3181 tctttgctgt tcttacactt gtatcaatac acatatggct catcattcca cagattacta
     3241 gattagtaat attttttttc tcaaggatac tttgcaaatc tgtttcaaag aaactatctg
     3301 gtgtgtgttt aattataatt tcttcattat ctagtggaaa aacaatttta tttatttctg
     3361 aaccatgagt attaggaaga aaaaaagaag ctgttttatc tgttgatata tgctgtatat
     3421 gaataactgg taaattgttt tttctaaaaa acagtagtat ttttttagca ttttcagcag
     3481 tttcttctga ttgaaataat tcacattttc catttttaaa ataatcattt tgaatatcaa
     3541 tcaatattaa agctatagac atgattatac cttctattta cttttattat aatactattg
     3601 taaaaaatgt aaattactta ctttttggta tgtataggat tacttattgt agcaaattcc
     3661 tttattatct agaatttctt gttgaccatg ttcaagcata tattcgattc ctatttcttg
     3721 cattatttcc actgctttta acattttttt accacgatta gtaagaaaat attcaacatg
     3781 taatggatat ccagcagaac ttattttatc aataatccca aaatcacgta actcttttaa
     3841 ttgttgaatc aacatttttt gatttattcc ataaatatta tgttgcaatt cagaaaatgt
     3901 tttattagat tgtcttaatt caaatataag gatagttttc cattttcctt tgattatgtc
     3961 atgtacaatt tcaagaggac atgtatattc agctcttatt ttcatagcat atcaccccca
     4021 gtaaaatgat aataaattat atcacttgtc ttgtgatatg acaaatatat atgaactgta
     4081 tataaatttt atgttttatt aagttctaaa tttcttctat tgtagttcat atttagtaca
     4141 taaataatta gtaagatata agtaaataaa tatataacat gactatagaa atttaacttt
     4201 aaaataactt atgataattt agaggaggaa tatatatgaa tatatcaaga aaagctatga
     4261 aaataataga attagcacaa aaaattgcaa ataagagagg tatttcagta gaagaagctt
     4321 ggagtgaagc agtaacagaa tataaaaata aatacgaaca tattgcatag atatttaaaa
     4381 atttagaata tttggtagaa tataatgatt ttaaatgata ctataaatta taaggtatat
     4441 cattattaac atagaaggag gatatctgct tgattgtaaa aatagataat actttagaaa
     4501 aagaattttg gcaatatgta tcacatgaag aaagtttaaa tttattcata attggatacg
     4561 ttgagaatta tggatttagc tctcaatatc aagatatatg gtctcaggta gaagatggaa
     4621 atataacctc tataatatta aaaaataagt caacacttat aatttatagt tttaaaaata
     4681 attttgatat aggagaaatg aagaatcata taaaagattt agatgtagaa agcataagtg
     4741 gaaaaaaatg tgtaatagat agactaataa gtaaatacaa agatttttat gaaaaactag
     4801 ataataaatt ttgtgtatta aaagaaataa aagaaataga tttttccaac atgaaggagt
     4861 ataaaataga aaatgctcag gaaaaagata ttgatgaaat aggaaaactt ttaaataggt
     4921 cagactataa agtaagtaaa aattacatag aagaaaggaa agaacattta aaagagggaa
     4981 atgtaagagc atattttatt agaaatgatg atactatgat tagcactgtg tcaactggta
     5041 tggaaactag ttttttggca atggtggtct ctgtaagtac agataaaaga tataggggaa
     5101 aaggacttgc aagttatatg gtttacaatt tgagtaaaga attattgttg gaaggaaaag
     5161 ttccatgtct tttttataat aatgatgtag caggtaaaat atatcataat ataggataca
     5221 aagagataaa tgaatggaca attcttttta aatagctata aaaataataa attttcgtgt
     5281 aattcttaac gtgtattgta taatcgctca aatacttgaa aggtgtctag tagatgggtt
     5341 tgttagcatt tatggtctcc ttatctaagt aaagttccct ttggaaatcg gtgaaatact
     5401 cttttacatt tcatgagtcc tataaaatct atgacataag aaagacccag ttacattgag
     5461 taattgggtc ttattatcat atatattgtg tgcttacatg atatagttca tttctataaa
     5521 cgtagtattt cgtaagtggg aaccaatttt ttaacaagtg attatttgaa caaagcaata
     5581 aggatatgct agcagatgga ttttgtataa tttaaaaatc aatatttaga ctctatcatg
     5641 tattttcatc atcataatcc aatttgaaat tgtatctaaa accagtttgc tatttccaca
     5701 gttacagtgg ttactagctt gttctgcttc tgtcataagc ctaaatgtaa gggatcggac
     5761 attgttgagt aaatcaatct ctttaccaac agttctataa tcaataaaat gatcttgtgt
     5821 tgcacctaaa atcaaaatgt cttggtttat attttttgca atagaatcta tttgataata
     5881 cttgattttc tgaaaatatt catagggtgt agacgcttca tatgcgtaca ttccatgttt
     5941 taaaccccat accaccatac tatcgccact tttcattttt tgctttatta taaaattgac
     6001 tagccatttt gttttgagtt ttagcagtag tctaagtaga ttttgcattt ttattggttg
     6061 tgaaccaact attatgtcta agaaattggg gaatacagac caagctacca cgcgttcaat
     6121 tcgtttttcg aaggctgctg ctcgtggagc aagaaaacct cccaaggaag cacctacaat
     6181 agttatattc tctaaatgaa aataatctaa aattgtctta acgggacgtt cccattgata
     6241 agtaaagtgt tttccctgca aacgcatcac tccaccttga ccaggtccct caaaaagata
     6301 aatatcaaat ccctgtgacg caagataaag cattgggaaa aagaattctt caaagtaaga
     6361 atcatttcca ccgtggagca atataacatc ttttacctcg ccttgcgctt ttgcatacat
     6421 tacaggtagg gtgatatttt catatggtac atgaaaaatt tgtacagttc catttgagaa
     6481 atattcagag tagtagttgt agaatagagt agttgctttt ttgtagactg atattttatc
     6541 agggtcacca tcatacataa aaaattcact catacgatag taagcaattg cattttctgt
     6601 gcgtccatct tgttcagctt cttgtgccag atacataagt tctgttttcc aactttcgct
     6661 atcgacaatt ttagaggaaa ctttttgtat atcttccaag cgccccccat cccacataat
     6721 aatcctgttt aactgaaaat taaaattggc atttgtatta aggtaatata gacctttatt
     6781 aaaagaaatt ttatttgttt tcaatgtcat cactcctaaa aagataatgc atagcaataa
     6841 agagtaatct ttaatgctat gcatttattg taacaaatat tagaagtact gactttcaaa
     6901 tagacgctat tggcggataa aatatatttt acattttcct ataagctcac ttgcagtaat
     6961 gccaagatat tttttgctgg aagctgagaa atgagacggt gaactaaacc ctgcgtccat
     7021 agcagctgag gtaatatctc cactttttaa caataactca taagccttgc gaagttttga
     7081 taaagccaaa tagctgttta gtgatactcc catttgttct ttgaaaagat gagaaaaccg
     7141 gcttttggac aattttactt cggcacatat ctcaaaaaag atttcattgt gaatgtgtgt
     7201 ggactttaga atatgattca atgcccattg tattctactg tctgtaatag acgaaatatg
     7261 ataatttaaa ttcaatagac ggaaagcttg ttttgaaaaa tcaatatagc tttgggacaa
     7321 tccttttacc tgacaagctg tataaatatt ttgtattcgt tcaactataa gattatctat
     7381 aacgaaaaaa gagtgattta gtaattggtg ttgactaata ttttgggcga gtatgcttgt
     7441 atcatctatc aagaaaacca acattttatt atctttactt gacaccgtat gcgatacatt
     7501 ggaatcaata ataattcctt tacattgtaa tgattcgccc ttatcaaacg tcacagataa
     7561 gttaccagac tgtgatataa taatatgttt tgcaagatgt ttatggatag ttggttgtct
     7621 atactctgta tctaaaaata tatggtcaat cattacacaa atggtagtca tagctgtcaa
     7681 ctccttgttc atagcttagc atattataca gtttttaaca agaaagctta gtgattacaa
     7741 gtatttaaaa atcctatttt aggcaatgaa aaataaaaaa ctctatcgag aattaaagta
     7801 tttataaata actatatttt tactatgatt catgatagag ttttttaaaa tttatgatac
     7861 tattttttat tatttaaata atcaagtgtt ttaagtttat aaccttcttt ttcccaatgt
     7921 gtaagaacct catctaatat ctcagtattt gttgatgaat ttggatgcag taaaactatt
     7981 gcaccaggat gagttcttga ataaattttg tttttggcaa attcatgagt aggttgtttc
     8041 ttttcatacc aatctacata agcaaaactc caaaatattg atttatatcc taaatcttgt
     8101 gtatatttta aagattgttc gctaaattta cccattggag gtctaaaata cttaggcatt
     8161 tcttttccag taacatcttt gtatgctttt tctacacttg taatttcttc tttgaatttt
     8221 tcaaaatctg taatacctgc cattgatgga tggctttttg aatgattaca aactaaatgt
     8281 ccttcttttt ccatacgctt tattaactct ggattgcttt ttatataact ttcaactacg
     8341 aaaaattgag ctttagcatt gtgtttttta agcgtatcta ataattttgg agtgtttcca
     8401 ctttcatatc cagcatcaaa tgatagatat ataacttttt cattgggatt tcctacataa
     8461 taagctccgt attttttaaa aaaatcagct tcttttatag gtgatggctg tttaccatcc
     8521 tccctagggt taaaatacca atcatattca tgtgtgtcga gtgttggact agaaatttga
     8581 gtttttgttt tatctaatga tttaaaattt atactagcaa ttccaaaaag tattagagca
     8641 aatgctccta tcataatgta tttttttagg ctatcttttt tcacaatttc acctcttatt
     8701 taaaatttaa agtatatttc ttataatata gtttgaatat ttatagttaa aaatattcac
     8761 atatacaaat aataaatgaa agaagtttac tgtaagatat aaagttgata ttaattatct
     8821 taaataaagt gtatataaat gataaaatat aaagagaaat gattgtaaat aagttaggct
     8881 ggtttaactt gaagggatat aaaaatggat aatataataa gtgtattgaa tgatgttgtt
     8941 tttttagata tagaagttag tggattagat tgtttaaatt cagaaatttt agaagttgga
     9001 gctgtcaagg ttaaagactg gaaaatatat acctatgaat cattaataaa aaacaaattt
     9061 gaggtaccta tagaagtatt ctcagtatgt aaaaatttag ataaaaatga tttagaaata
     9121 gctaatgaaa tagaactggt ggaagataga cttgtaaatt ttgtagaaga tagtttcatt
     9181 atatgtcatg atttaagtct gaaaaaaaag ttttttgagt atcatatgcc aaagttaaaa
     9241 aacaaattta ttgatttaat tgaattagca gttattttag aaccatatca taaagattat
     9301 agcttagaat acttaaaaaa tactttaaca aattgtaatt ctaaagtgga aaatagagct
     9361 ttatcagatg ctattgatat aataaatatt gtaaattgcc ttttagtaaa atttaataac
     9421 tatgaaaaaa ctactttgga gccattgagt tttaaaataa attcatatct taaaaaattt
     9481 aatcttccaa catgggaatg gagcaaattt ttagaagagg caaattatga tttatcaaat
     9541 aatataaata taaaaaaaga atataatata tttgactcaa aagaagaaaa gaagaaggaa
     9601 agagaaacct taaaaatttt aaatgaagaa gaaaaaaatt atgaagaatt attaaaatac
     9661 aaaactattt gggagaataa agaaggattt acatatgaat atagacctgg tcaatatgag
     9721 cttactaaaa caataagaga gttgtttaga aatagcgaag atgaagaaaa aattgcatgt
     9781 atagaggcac caactggtat aggtaaaagt gtaggatatt tattgcctgc aatattagag
     9841 gctagaatta ataaaaaaag attattaatt tctactgaca caaaggaatt gcagatacaa
     9901 ttaataaata aagatattcc aaatgtgtta gattctttgg gtctaaatgg aaaagtaagt
     9961 tacggatata taaagggaaa aaataactat atttgtatag atagactgga agcatatata
    10021 gatgattatg agtctcaaaa ccctactaaa ggagaaattt tatctttaat atttttgaag
    10081 agattagttg aaggtggcaa gtatggagat atagaagaaa taaattattt agtgtttgac
    10141 aacttcaagg aaataagtac ccacttaaga aatgtaagtt gtgacccaaa tatgtgcaga
    10201 cctaaaaaat gcaaaaaaga ttgtttatat aaaaacagaa tagaagaatt aaaagaagaa
    10261 catataacag tagtaaatca ttcactatta gctaaatggc cgtataagga tgaaaaacct
    10321 ttagaaaata taatagtaga tgaagcacat aatttgactg aaaaaggata tgatttcttt
    10381 tcaagcatta taaattcaaa gtctttaagg tatttattac aagaaattta tccttacgag
    10441 tttattcaaa atagtagctt tatatataaa aaatatagta gaaatatgag aaaaataaag
    10501 gcttttgata aattttataa tgtattaaaa attggaagag aagataaaca aaaaattgct
    10561 agaagtataa atctcattat tgaagagata gattcaatat taaagtttgg taattgtaat
    10621 gaatataata atgtaagtaa ttataattta agatgggaac tgaatttgca aatagatgaa
    10681 attgtgggaa aactaaaaaa ggatggtata gatactgaaa taagttatag agcctatagt
    10741 gaaaagataa agttgagttg tgagaaaata ataaaaaatt tagtttcaat aataataata
    10801 atttatagga atattgatga tgatagtata gataaagaag cagatatata taaatttgga
    10861 aaggcaaaga caagagattt agaggatata aagattatat ttgaaatctt tttagagtat
    10921 gatgaaaagg atgattatgc aaggatagtt gaaattgata agaattataa tgactttgaa
    10981 tttcgagtag taccattaaa aatagcagat ttatttgaag aaaatatttt atctcaatta
    11041 gaaaaaggaa tatttttatc agcaactttg agtttatctg aaagtatgtc ttattttaaa
    11101 aatacattag gaatagacag agttaagaat gtggaaaaga ttatagaacc aatttttgat
    11161 tataaaaata gagtctctgt agttggattt tctgatattt gtgagtacag aaattctgaa
    11221 tttccaaatg agatgagtaa aattatatct aatatatcaa agattacaga aggtcataca
    11281 ttagctcttt ttaatagtaa agatagacaa gaaaaaactt atgaaatatt gaaaaaatac
    11341 ttacatagtt ttaacttaga aatttatgct gataaaaagg ggattagaca ccttaacgat
    11401 ttaaatagaa aatgtgtagt acttggctca aaaggatgtt ttgaaggcgt agacattcca
    11461 ggggatggtt tggtttgtgt aactttagac aagcttccga atctaaatcc aaaagaccct
    11521 ttgtatttta ctataatgaa gaagtatggt atagactact atactataaa ttatcctcaa
    11581 atgaccataa aggtaaagca agctatgggg agaattttaa gaagcaaata tgactatgga
    11641 tgttttgtga tttttgatgt aggaactaat ataagtgttt taaagagatt agagaaagat
    11701 ttacacgatt gtaaaatttc aaaggttaat agcaatgagt tttatactta tataaggcga
    11761 catttaaata aatctagaag tttaatacta aaatctgtta tatttgatac tataaaagcg
    11821 ttgaatgttg atgctaaaat ggataacaat gatgttgata aagatattat aaaaaaagat
    11881 ataaatgaaa atataagaca aagagctgta aaaggagaag tgtaccatat tgatattata
    11941 aaaaaagata tgaaagtaaa atattttgat agaaactatc ttataaattt agatatattt
    12001 atgagagaag aagataaaaa ttaagagtgg gagtgagata tttggcaaaa caaaagtttt
    12061 atgctgtgaa aaaaggtaaa aatataggtg tatataatac atgggatgag tgcaaaaaac
    12121 aagtaaatgg attctcagga gctgaatata agagtttttc tacttttcaa gaagctaaag
    12181 aatatattga tgggtcagaa aaattgagtt ttcaagaaga taaggagttt atagaagcat
    12241 atgtagatgg aagttatgaa cattcagtaa aaatgtatgg ttcgggtgtt gtgattttaa
    12301 aaaataatga agttataaaa acttatagtg aaaaaggaaa agagaaaact ttagtaagta
    12361 tgagaaatgt agctggagag atagaggctt ctaaaattgc aatgcagtac tgtattgaca
    12421 ataatgttca aaacttgatt ttatactttg actatgaagg gattgaaaag tggtgtactg
    12481 gagtttggaa aacaaataaa gaaggaacta tagcatataa aaatttctat gacagtatta
    12541 agaataagct taatgtaaaa tttacaaagg ttaaagctca ttctggaaat aagtataatg
    12601 aggaagctga taaattagct aaaaaagcta ttggtgtata ataaaaaaat atttatacat
    12661 aattacatgg tataagagta tatctaaatt cctactttat aattaaacaa cttgtaatta
    12721 aacaacttgt aattaaacaa cttataatta aataaatttt gattaaaaaa gcagattgta
    12781 ttatgaaaaa ataagtatct aatttataaa caattaataa tagtattaat tagatacaac
    12841 ttatttaata taataaaatc tgctttttat ataactataa aatcttccta cattctatta
    12901 gaattgccca taaatacctt caagttcttc ttttaatact tcagggtcat ttataccaat
    12961 agacatggtt ctagccagta tatttgcttg gtcataagtt gatgtccatg agaatacacc
    13021 acctagacaa tttctaagaa catattgagt ttttaagaat attgataaag catcatcata
    13081 tgacattgca aaatctccat ccttaactaa atacggaact tgagcagtat tatcaaatct
    13141 atattcatat ccatttttat ttatataatc ccttctaagc tcatcataag ttcttgttat
    13201 agtggcacct aatcttccat aaaatggtat accgagaagg attttttcag aaggcattcc
    13261 agcattctca agatttctca ccattgcatc aacactatat cctggcaaag ataagtctga
    13321 atcaaaaaga tttgcttgat gttttctacc atttgggcct gtttcacctg ctgtaaaatc
    13381 ataactcata agattaaaat aatctattat aggagctatt ttatctattt cagcacttga
    13441 atttatatat cctctatctc ctgttccagc tacactaagc catttatcat ctcctataac
    13501 atctcttatg gcagttagta agagtgtaaa gttttctcta tcttgaggtc ttgatgttat
    13561 tccagatgca ctacttccag gatattccca gtctatatct attccatcta aagcatattc
    13621 atttatcatc tgattgacct gtcttgcaaa attatatcta gatgtaggtg ttaatgctgc
    13681 atcagagaat ccttcagctc cccaacctcc aatagctaca attactttta agctaggttt
    13741 ttcaccttta agagcaagta attgatttaa aaatctagga taaggaataa acaaatttcc
    13801 agactggtct atctcagcaa aagcaaatat aactgcatct aatagttgag catctacatt
    13861 agttggattt ccaagaacat attctgctac aattggattt atatctggac agtttgcatt
    13921 ttcaactatt ggattgtatg ggtctgttat ttgtggtcta actaattttt ttgaatcttt
    13981 taaagttttc atagctattt ttttagtatt tttttcgcta gtataatcgt agtttttata
    14041 attatgttta tagaaatctt cataactact atcttctttg ttatagctag aatttatttt
    14101 gtcgcaagat tcatctttat catagttaaa attcatttca tcacaagact tatctttaaa
    14161 cttatcttgt ttggagttgt gaactttgtt agtattttta gtatgttttt tctcatggtt
    14221 gcaatcatct ttaatatcag tcttgtgttc ttgtttacag tcaagagctt tgttcaggta
    14281 gtcatgatgt tcatgttcac agttacattc attttcaatg tttttagtat gttctttttt
    14341 ccagctacaa gtattatcaa ttttcttgct cacttcttca tcattataat tatctggtac
    14401 aaaacataag taccagtcca tacatgaata tttcttatta caactgttaa ctctattttt
    14461 taattcctta tagtttttag gataaggtaa aatcactggc attccaggaa accagtttgc
    14521 aggagtaact atattatctc tatcactagt ctgaagtgca tctactattc taagtatttc
    14581 tggaatattt cttcctgtag ttagtggata ataaagaatc gttcttagaa tttgattatt
    14641 atctataata aatacagagc gaacagttga tgtatcactc attggttttg atatcatgcc
    14701 gtataacttg gcaattctca tatctctatc ttctataata ggaaatggaa tttctacacc
    14761 tgtaagtaaa gaaatattat acatccaagc taaatgtgaa ctgttactat caacacttag
    14821 accaattagt tctgtatttc tttttttaaa ttcgtcataa tatttagcaa aacataaaaa
    14881 ttctgtagta caaactggtg taaaatcacc aggatgtgaa aataaaacaa tccaattacc
    14941 cttatagtca gagagtctaa taggaccatt tgttgtattg gctttaaaat caggagcctt
    15001 tgaccctaaa cttggcaaat ttggcatgta aatcacccct caataaatta tcatttattt
    15061 tattctatta attaatacat attagtgtta ctattttatt aaaagttaag taatccttat
    15121 gtcaaaaaaa gatatttatt aaaaagattt aatattttcc taatataaat gacaatagta
    15181 attgctattt ttttactaat ttggtatagt aatggataag gggtagtgtc aattttagtg
    15241 attatacgag gtgattggat tgaaaaaaat tctaagaatt ttagttatct ccatgatgat
    15301 atgttttgca atgacttttg cattagtgtt aataaattca gttatgggag tacatatagg
    15361 attggattat tactttttga tgggaagtgt gcttacagtt tgtttaacaa ttggaattgt
    15421 tttatgcaat gctagaaaaa tatttgatag caaagctata cacaagacaa gaacgaaaac
    15481 tgtcagtact aataaaaaac aaaagagtca ttctagggat ataaaaagaa agatatcata
    15541 atttatgtaa aggaaatatt tatgtataaa ataatgattg ataggtaaaa taaaaacacg
    15601 atttaacttg tgtttttatt ttttttcaag aattatgata taataaccaa taagaaattt
    15661 agtttaccat aaaatataaa gattattaaa tggagaggga actataatga attttagaga
    15721 tttatttgag aaggctgtag attttattga tgaaaaaagg aaatctatag ttgcgatttc
    15781 attatcaaca ttaggtgtaa ttgctttgat aatagtattt ttcttaagta gtaacgagtt
    15841 tagtgtagga aatgaagcta atgagttgtt aaagattata gagaaaagac agtattctat
    15901 agctgttgat tactacacaa gtatagaaaa aaagttttct gattcaaaaa tggaaaggtt
    15961 taataagtct gtttctaaaa aaataaataa attgctatta aatagtggtg ataaatattt
    16021 agatggagac ataagtcaag aaagttttat tggattaata aatactgtga aagaattaaa
    16081 caaaataagt atagatgtgg atgacttatt agctcaagct gatagagtta gagaaatgta
    16141 taaagaagaa aatactactt atgatattgc cattaactac ataagtactg tttcaatatt
    16201 aaatggtatg ggtagtaacc tagatgtata caaacagaat atagaaacaa tcaaagagtc
    16261 tagagatgtt tatgactcag cagtaaaaga ccaaaaagca tataagtatt atgaagctat
    16321 tgaaaagtat aataaagtat taaaagaaga tgaaaagtat tacagtatgg ctcaaaatgg
    16381 gaaagaacaa tgtattgaag aaatgtatga ttactatata agtagagctg aagaggcaaa
    16441 tacttctgga gattatgaaa gagcattaca atatattgag tatttaaaag aagattattc
    16501 agatgatgaa aaggtacaga gtttagaaaa aaaatataaa aagaatttat cattgtatac
    16561 cttaacatct gatgacatta taaatgtaat agctaaaaaa agtggcaaag acaaggcaaa
    16621 tctatctata aattcacttc cacaaatgat aaaaaataat aaatactatt atgctgaagt
    16681 atatgagtat gataaattaa taaatgaagt tttggtaagt gcaaaaacta aagatttata
    16741 ttcgtataaa gatggtaaaa aagattacaa agtagattat ggtgatggat actttagaat
    16801 attagaagat ggaagttatc aatttggtat tacaaaagat aaagctaagt ttgtgttaac
    16861 taatactctt gatgaaaaag aaaataagta taaaaagatt gagatattag atatagagaa
    16921 agcagataga tatgtaaaaa gtaaaaagag tttagaagaa ttgtttggaa aatataaaaa
    16981 tatttattat tatgctgtag taaataaagg cttatttaga ggcaaagaag tttatgctat
    17041 taatatttac aatgaaaaaa tatatgccat atcagaaaat ggactaaatg aatattaatt
    17101 aataatatta aattaatata taattaaaaa gtttttgggg ttttaaggcg cattatgtag
    17161 taatataata atagggatat ataaataatt ttattgtaag gagaagtatg ggatgagtaa
    17221 tgtgaacaaa aagctagtta tagctattgg agctgtagca ttagtagcaa taatttttat
    17281 aggcataatg tgcatgcaat ttaaagggga gaaaatagca aaaaacacat atgttaatgg
    17341 agtagatatt ggaaaattaa ctaaatcgca agcaaaacag gaattagcta aaaaatacaa
    17401 attagagaat gttgagttta attacaatga taaaagttgg aaagtaaaga gcaaagattt
    17461 aaatttatct actgatctgg ataaaacagt agaaaacgca tataatttaa atagaaagag
    17521 tagtttcttt ggcaatctat caaaaactat ttcaacaaat tttggcaaaa aaagcaactt
    17581 agtagttgtg ataaattatg ataaaaataa attaaaagca gaaatggaaa aaatagctaa
    17641 agaaatagat gtagatgtaa aagatgctac acttgatata agtggtgaaa aagtcaaggt
    17701 tataccagat tctgatggtc ttaaaatgga tatttctaag agtatggaga attttgataa
    17761 tcaaactaaa aaaggtaact ataaaaatga gttagtagta aaagctactc cagcaaaagt
    17821 aaaaaaagag caacttacta atatagatac aaatttaggt acgtattcaa caatatttaa
    17881 aacttctcaa ataaatagaa gtataaacat aaaattagca acagataata taagtaatgt
    17941 attacttatg ccaggagaaa ctttctcatt taataaacat acagggaaaa gaagtaagga
    18001 aaatggatat aaaagtgcac ctgtaataat ggaaggtgag atggaagaag attatggtgg
    18061 aggagtttgt caagtttcat ctacgttata caattctgtg ttatacgcag gtttagaaat
    18121 tgttaatgta aaaaatcata ctataccatc aagttatgtt ccaaaaggaa gagatgcaac
    18181 tgttgcagat agtggaatag atttcttatt taaaaataat ctaaagcatc cagtttacat
    18241 aaaaaattac gtttcaggaa atcaaattgt ttgcaatata tatggaagtg cagaagataa
    18301 acaaaatata acgatatcaa caaaattaga tggcgtttca caaactacaa tgaaaagagt
    18361 taatgaccct acaatgccta aaggtaaaga aaaagtagac aaaagtggaa gaaatgcata
    18421 ttctgtatca acatatagaa catttaatga tgcaaatggt aaaaaaatta aaactgaaaa
    18481 aatagctaat tcatattatc ctaagaagga aggtattata ttagttggga ctatggaacc
    18541 aaaaccagag gaaaaaccaa atacagacga aaataagaat aatcaaaata caaacaatca
    18601 aaatccaaat aatcaacaaa aaccagaaac accaccaact gataataagc ctaatgagac
    18661 acaaccacaa ccgcaagctt aaagttctca agaataggat ttatgtagag taataaaaaa
    18721 tataaatcta aataggaggg attactttga atttaaataa tataacgaat tacgttcaaa
    18781 gtatttgcga gaatatttct aatgtattgg atgtagatgt tactttagtt acaaaagatt
    18841 taactaggat agcaggtaca ggaatattca gaggtaaaat aggagagaca atatcagaga
    18901 agtcagtgta ctctcttgtt ttaaaagatg gaaaatccta tgttataaat aaggaaatag
    18961 aagagaactg taataaatgt gcaaatagag aaaattgtaa agaattagct gatatatgta
    19021 ctcctgttaa aatgggagaa catatacttg gaatcttggg tatagctgcg tttaatgaag
    19081 agcaaaaaga aaagatactt tcaaaagata aggagttaac tgcttttgta aggagtatgt
    19141 ctgatttaat atcttttaaa ctagatgaac tttataaaca agaagttaag actatagatg
    19201 accttgagag ggaagctata gaaaatgcca taaagaaata tggaagtaat acagaaggta
    19261 tgaaaaaagt agctgaggca ttaaatatag gtatagctac actctataga aaagtaaaaa
    19321 aattcaacat taaaagttaa tagtattgaa aaagaggtaa cctttttatg aaaagaagag
    19381 gattaccttt tttattatga gaatggtgga aaaatatgta tagttttgac ttgacatatt
    19441 aaatatgtta tcttaaatat atattttaga gtggaggtga gtattatttt agttaaagat
    19501 ataaaacaag acatagaaag catgcctaga aaaattttag atatatcttt gatagaagat
    19561 aataaaagtg atttgacttt ttttaatata gaagaagaag acggtgatga aacattaaaa
    19621 gcattaaaac agagttatgt gactacaaat tataaagaag aaactctatt aaacttgcaa
    19681 ggagctttaa attcaaagtc agacacaacg tctaaggagt taaaattaga atcatataaa
    19741 agatataaca atgcattgga tttagcatat aaaaattata taactagtgc cattaatatg
    19801 gttaataaag ctctggagat aaatcctaaa gatattgata tactaaatct tagaggtctt
    19861 ttaaagttat taaaatgtga ttttgctaaa tcatttgaga gtttttatac tgctttatgt
    19921 tatgagaata atcatatatc tagaaaatat gtaaatctaa tttcatctga agattttaaa
    19981 acttttttag gaagatacaa tcattctata agatttataa atgaagaatt aaattatgag
    20041 tcaatacata ttttagagaa cataattgaa gaagagcctg agctaataga gccatatgta
    20101 atcttatctt tgttatatga taaactaggt aatgtaaaaa agagagaagg atatttagac
    20161 aaacttaaag agctagataa agataatcct gtatttgaaa aaaatgaaga agaaaaagaa
    20221 gatacaagta aaaaggaaga aataagaaaa gtaaaaagaa agaaaagtat tttaccatat
    20281 attatagttg gctgtgtttt aataggtatg gggatatatt tgattcaaag caaaaagaga
    20341 atagaaaact tgaataacca aataagtagt aaagaggaaa agttaagtga aactgataaa
    20401 aagttaggag aaacgagtaa aaaattagaa aaaacgaata aggaattaaa tgaggttaaa
    20461 aataaagaac cagaaagaga gataactgta gctgatgagg aagatttata ttatcaagct
    20521 ctaaatttaa agaaaaacaa agaatatgaa aaagccatag ataattttaa aagtgtagtt
    20581 tcttctggta aaactaaaaa atatatttct gagtcaatat atcaattagc aataacaaat
    20641 aaattattag gaaataagga tgaagctata aaatattaca aaaaatatat aaatacttat
    20701 actaaaaatg accagtatta tgatgattca tattacgagt tgggtatgct ttattatgat
    20761 aatggcgatt taaaaaatgc acaacagact ttttatagtt tgagaagtga agttccagac
    20821 agtatgtata acaattcaaa aataaaagaa atcttaagtg aaaaataggt ttatatagtt
    20881 aagttttttg aaacaaccaa gtatgtattt tattaaatta aaataaaaat aaatttaaaa
    20941 agagattgtg tcaaattata actttctatt ttaaagaaag atatttgctt gttgataaaa
    21001 ctacaaatat atgatttgaa gcaatctctt taatttttgg aggtggaaaa tgaaagtttt
    21061 caatcaatta gtaataattt tatctatctg ggtaatagga gagtatataa gttcctttat
    21121 acaaggaatt atacttattc ctgggagtat agttggtatg ctattattat ttctactact
    21181 acaatttaaa gttttagact tgagtagtat agaaaatgta agtggatttt tcctcgataa
    21241 tatggctata ttttttattc cagcaggtgt atcacttata aagtcattag acctaataag
    21301 ggaaaatgta ttagtgcttt tattagtcat atgtttaagt acactaatag taatgtatac
    21361 tactggaatt attgtggaga aaatgataaa aaagaaggaa gaaggacaaa aaaatgtata
    21421 atgtattaca gacaccagta tttggtataa tagtaacaat agtttttttc aatttaggaa
    21481 gatacattca acgaaaaaca agtaatccta tatgtaaccc tttattaatt gcaatcgtag
    21541 gaataatatt gtttttaagc atatctaaaa tcccttatga gaattacaag ataggagctg
    21601 atagtctaaa tttcttttta ggtcctgtca cagtagtact tgcagttcca ctttataaac
    21661 aatttgaatt atttaaaaag catatgtttg agattattgt aggaataggt tgtggtatag
    21721 tgatttcttt tgtatctgta ttgataattg gcaaaatagc taattcagat gtaagtataa
    21781 taaattcact aattccaaaa tctataacaa caccaatggg aatatcttta gcaaattctt
    21841 taaatggtat agaatcaata acagttgtag ccataatttt tacaggtatt tttggtggta
    21901 tggttgcttc tacagtattc aaactgggga atataaatca tccagttgct aaaggaattg
    21961 ctcttggaac atctgcacat gctttaggaa ctacaaaagc ttttgaactt ggagaaatag
    22021 aaggagctat gagtggtgtt tctattggag tttctggtac aattacagta atactaattc
    22081 caattataat gaattttata taaaaaataa aattaagacg agtaccttga atacttaaaa
    22141 caaaataaaa taaaaaaaat ttaaaataaa aactgaacga aaaaaatgca aataatgaaa
    22201 taaaaaaatc atgtactgaa attataaaaa gaaaaatttc atttaggaat taattataaa
    22261 gagataatta ctaaacttga atttgctaaa ataaaataaa ttactgcgaa aatagatatt
    22321 tagaaaaaaa tactataaat ttactatatt gcaagttaaa taataagcag tatcatatta
    22381 tgctagaaaa agtttcattt aaggcataaa tgagatgatt tgaacgtttt taaagattag
    22441 aatataaaag attgcactag acatatatga aaaagataat ataatagatg atgtaataga
    22501 tgacagttca agaaattata aaaaaaattt atttgaaata ttatctatta catcaggaat
    22561 aatatatgta agagtaagct tttaaaattc taaagattta gaaagattga agggagaaag
    22621 aaatgagtga agttaagaat accctacaaa aacatccagt tttaagatat tcaacaatgc
    22681 tatttgggat gttgatgaca tctataggaa taaatgggtt cttaagacca gcacatctgc
    22741 ttagtggagg tgctacaggt atagcaacat ctataaacta tttgacaaat ataaatgtag
    22801 gtttattaac atttttaatc aatattccaa tatttatctt agggttcata taccttgaaa
    22861 aagagttttg tatttcaagt ttggtaaata tgattgtatt ttcattatta ttaggagcaa
    22921 ctcaggaaat aagtaatatt atacctatac atgatatatt gcttcaaagt gtatatggtg
    22981 gtatattatc tggtttagga gtcggagttg tatttagaac taggtcttct caaggtggta
    23041 cagatataat agctgcaata ctaaaaatta agaagaatat agaaatgaaa gacactgctt
    23101 tagcaataaa tggcttgata gtacttacag gaagtttttt atttgggttg gatttagcat
    23161 tatacactct tataggtcta tttctaaatg cgtattcaat gagttttatt aaagatgcaa
    23221 tgaattacca aaaatctgtt atggtaatgt caaatgaagt cgatttaata gcagaagata
    23281 taatgaagag tttagttaga ggtgtaactt ttttagatgc agaaggtgca tacactcatc
    23341 aaaaaaagaa gattatatat acaatagttt catcaaatga gataccaaag ataaaagata
    23401 tagctttgaa gtatgataaa aaggccttta tatctgtaaa tgatgttaca gaagtaaaag
    23461 gaagagggtt taaagcaaaa gatttataga aaattttaca agctgggagt ttataatgta
    23521 aatttgtata ttatatctct cagcttattt aaatttagta tatgaaaata aaggttttat
    23581 caatgatttg tgtatcactt taaaagatat cattttaaaa ttaaaattga aaaaattact
    23641 caatatgtag aaaacataac cactattagg atataataaa tttaatagat ttagtaaaat
    23701 atctaggaat aacgttggag gaatagcatt atgaatttat ctaaagaata tgttaatttg
    23761 tatgataatt atttgaaata tataaatgaa gtaaacaaag agattagaag tataaagaac
    23821 atgaagaaac gtgttttaaa aaagggcgat tttgctccag aaaatgaagt attagaattg
    23881 gaaggaaaaa caatacgcga tatagatgat gtcgatacaa aaaaaccaaa aaataaaata
    23941 tataaatttt caaatgggga tgtgtatgta ggaaaatttt tagaaggaaa gatggaaggg
    24001 caaggatcat atactttttt tgttgatgaa ggaacggcta tggagtacat aggagagttt
    24061 aaagaagaca aaaaaaacgg aaaaggaaac tttgtatttt caaatggaaa tgaatatata
    24121 ggccattttg aggaagatat gatgaacggt attggaaata tgttatataa tagcaaagat
    24181 gaatatattg gaacttggaa aaatggaaaa aaagatggaa aaggtattta taagtggagt
    24241 gatggatgta tatatgcagg tgaatttaaa ggtggaaaga tggaagggta tggtatttgc
    24301 tataatagta aaggggaagt actttatgaa ggagaatgga agaataattt gattcatggt
    24361 aaaggaactt atatatggga aaaaggtaaa aagtatatag gtgaatttat gcatggtaaa
    24421 aaacatggac aaggaacttt ttatctaaat aatgaattgg tttatgaagg gacttggaaa
    24481 tttgataagc catccatctt cgacagaaca ttagatgaaa tattttcatt aagactatag
    24541 ctttatctat taatagataa agcttttttc taatacttac tgtaaataag tatgaatgat
    24601 attgattagt atacactatc aatattaact caataaatgt gatattaaaa atttttgatt
    24661 gattttaaga aggagggata tattgaagag attaattgct ttagtgttag taatacttat
    24721 tgttttattt tatagccctg aattgataga agaaggatat gatttaaaag aaaaattttt
    24781 tcaaagtgaa atatggaatg aatttttaga caaaataaat ataaataata attctaagaa
    24841 agataaaaaa gaacaaaatc aaaatttaca atcaaataat actgaagggg agaacttagg
    24901 agagtcagat ataaagaatt ttgaaaaaat aagcttagga gataatttaa gctatgtttt
    24961 atcaagtatt ggtaaacctg gtagaattga tattagtgaa tatggttttg attggtatgt
    25021 atataatcaa tatggaaaag aatttgcaat ggtcggactt gaaaatgatg aagtagtagc
    25081 actttatagt aattctatta attcatgtga aaatcaagat ataaaactaa atcaagatag
    25141 acaaacagtg agaactaaga ttacaccatt aaaatataag agaaaaggaa ataccagata
    25201 tataataaac tcagaaaatc aatatgatat aataagtaaa gaaggtaagt atattacaat
    25261 tttctacgat attcatgaag aaaatagagt ttgctcatat ttaataattg ataaaagtac
    25321 tgaagatgag tttaaaaaat tatatccaga tgatagagaa gaacttaaaa aatgttttga
    25381 acttgaagtt atagaccttg taaatagtgt tagaaatcaa agaggattaa actcattgag
    25441 atacagtgaa caggcaactt tgagttcaag aaaacatagt gaagatatga gagataataa
    25501 tttttttgac catataaata agaagaatga aactccattt gacagaatga aaagagaagg
    25561 tatagtatat acttcagctg gagaaaacat agcagcagga cagattaatg caatatatgc
    25621 gcatgaagct tggatgaact ctgaaggaca tagaaaaaat attttgggga actataataa
    25681 tattggagtt ggagtaatat ttggaggaag ctataaaaca tattacactc aaaattttta
    25741 taaataacta aaatatttga aaggaagtta aaaaatgaca tcatggaaaa aaaagacagt
    25801 atataagtgc ttaatagcag tagtcttgtt ttgtggaata gtgttaatat ctaattttag
    25861 taaagtttct gctttgatga tggatactaa tggaaatgtt ttgattaaac atggttcaag
    25921 ggaaaaaaag ctaatagcaa ttacctttga tgatggtcct catcctaaag aaactagtca
    25981 agttttagat gtattaaaga aatacaatgt aaaagctact ttttttatag ctggaaaaca
    26041 tgcaaaatgg tataaagaac cattagtaag agcaagtaaa gaaggtcacg agataggaaa
    26101 tcatactttc aatcatcctg atataagtaa tttaagttct agtcagatag aagaggagat
    26161 tgttaagtgt gaagacattt tgaaagaagt aactggaaaa aaacctacat tatttagacc
    26221 accatttgga agttatagag aaaaagactt aatagaaatt gcaaaaaagc atgactataa
    26281 agttgtttta tggacaggtg tagatgtgaa agattggaaa aatccaggag ctaatagcat
    26341 tgcagataaa ataattaata aagtaaaaaa tggagatata atacttttgc atgattatgc
    26401 aactaatgat acagttgaag ctttagatat gtttattcca aaaatgattg aaaaaggttt
    26461 taaatttgta acagtttctg agttgataaa ataattttta ggggggagat ttacagtatg
    26521 attcttatga tagacaatta tgattctttt gtatacaacc tagtccaata tatagaagaa
    26581 ttaggggaag cagttgtagt aaaaagaaat aatgaaatca aaataagtga cattgaagaa
    26641 ctaaatccag aggtaattgt gttatctcca ggaccgtgtt ctccaaaaga agctggtatt
    26701 tgcatagata ttgttgagca ttttaagggg aaaaaaccta tactaggaat ttgtttaggt
    26761 caccaaacta ttggatatgt ttttggagga gatattataa aagcacaaca gcctgtgcat
    26821 ggaaaagtat atagtatcaa ccatactaat aaaggagttt ttaggggact taaaaatcct
    26881 ttaaatgtca ctaggtatca ttcactaata attgattcca atacagttcc aaaagaatta
    26941 gaaattacag caattactga taaaggggaa ataatgggga ttaggcataa gaaatattta
    27001 atagaaggag tacagtttca tccagaagct attttgtcag agtatggtca tgaaatgctt
    27061 gaaaatttta taacagaagc tagagaaagg gtacatatgt aatatgataa gagagataaa
    27121 tactaaatta aattcttttg agatatttac tatttttaga aatgaacatg acagttttat
    27181 attagacagt gctatggata aagaaaaatt gggaagatat tcttttataa gtagccaacc
    27241 atttaaggta ttaaagtata aggatactga tgaaaatcct ttagaagttt taaaagaaga
    27301 actacataag tatagggttg taaatgatac taatcttcca tttgtaggag gtgctgtggg
    27361 atatttatct tatgatttag gtaattacat agaaaattta cctagaactg ctgtagatga
    27421 tattgagatg cctgatatgt attttggatt ttataatcat gtaatagtta tagaccatct
    27481 tgtgcaaaaa acttatatag ctactccaaa catagatatc gaattagaag aaaagataat
    27541 agatgatata gaacaaagaa tattaaaaga agagaaaaaa ggtatagata gcatatgtta
    27601 tgaagaaaaa gaagtaacac ctataagact taaatctaat tttacaaagg aagaatttaa
    27661 aaatgcagtt caaagtgtta gagagtacat aagacaagga gatatatatc aagctaattt
    27721 aacacaaagg ttcagtggag aaacagaact tacaagcttt gaattgtata gggacttaag
    27781 aagatttagc ccagcaccat ttggggcatt cttaaacttt gaagatacac atatattatc
    27841 aaattctcca gaaagattta taagatgtgt taataagaga atagaaacta gaccaataaa
    27901 aggtactcgt ccaagaggga aagataaaga agaagattta agacttcaac aagaacttag
    27961 aaatagtgaa aaagatagag ctgaactact tatgatagta gatttagaaa gaaatgatat
    28021 tggcagaata tctaaaactg gaagtgttaa agttccagag ctatttgtaa ttgaaccata
    28081 tgcaaatgta aatcacttag tttccacagt tgtaggtgag ttaaaagatg ataaagatgc
    28141 tactgatgta ataaaagcaa cttttccagg ggggtctata acaggagcac ctaagattag
    28201 agcaatggaa attatagacg aattagagcc aacgcaaaga aatgtatata ctggttcaat
    28261 aggttatata ggttttaatg gtgatatgga ttttaatata gcaattagaa caataatcaa
    28321 aaatgacaaa aaagtctatt ttcaagttgg aggaggaatg acttgggatt ctgacccaga
    28381 tgaagaatat caagaaacac ttgataaagc taaatccata atgaaggctt tgaggggata
    28441 ttatgaagaa taatgtaggt tttgatagta gtttaagtaa atttggaatt ggtttgtttg
    28501 aaactattag agttaaaaat ggaatagcag tagatttaga tatccatata gaaagaatgc
    28561 taagttcaat aaattgtttg gatttagata taaactataa aaaagatttc ttgataaatg
    28621 aaattgttac atatataaaa aaagaaaatg tcattaataa agcacttaga attactgttt
    28681 ttgatgaagg ttataatata tctattaggg atattccata taatcaagag acgtatgaga
    28741 aggggtttaa attagctata tcgccaatag ttagggggaa tagtttaatt catagacata
    28801 agactactaa ttattttgaa aacatatata ccaaaaatat cgcaaataag actggttata
    28861 atgatggtat atttttaaat tcagaaggtg taatattaga atgttctatg agcaatattt
    28921 tctttataaa aggagaaaga gtgtacactc ctagtgatag attaccgata ttaaatggaa
    28981 taataaaaaa aaggattata gagatttgtg acgaattaca tatagagttg atagaaaatg
    29041 aaattaatat atcagaaatt agtagttttg attttgtttt tgtcacaaat agtcttatgg
    29101 gcgctataaa ggttacagaa attgacaaaa taaaatttaa taaagaaaat gttgtttttg
    29161 ataaaatagt gaagttatta gaataaatta aaatattaac aatttgttgg agacaaaaga
    29221 tgataggttg tatttatgaa gtatacaatg aagagatgac taaaataata gaaaaccaaa
    29281 acactttggc tgtatattta gtaggttcta gtaaagacgt agattttact ctttatgatg
    29341 tagagataaa cgatattgat gtgttcgttt ttgtaaaaga aggggaaaaa caagagagaa
    29401 tactgtttaa aaaaaaggga atagaatttg atgtaaatta cttttcaaaa gatggtgtaa
    29461 aaaaattatt atcaaatagg gaatatttct ttgtgaaaga aatgaaagat gctaaagtac
    29521 tgtttgatag ggagaatata tcaaatatta taaaagatat aagtagagat atttacttag
    29581 aaggacccag taaaatgtca ttagaggaaa agtcttttat aaagcaagat attggagcaa
    29641 aaatatcgaa tttaaaaaat aaagaaaaat ttgatgtttt tgaatatcat tttttgacga
    29701 atttatattt aaaagatata ataattgggt actttaatat aaatgataaa tgggtaccaa
    29761 aagacaaaaa attgctaaaa gttttaaaaa aagaaaataa tgagcttttt gaactagcgt
    29821 caaaagtaag tgaaaattat gactatcaaa gacttttaga tgtttataat tatattttta
    29881 aagaaattga gacaaaagag gttataaaac taatcttcta gtcacaaatc aatgggggga
    29941 gtttaaatga ataaagttga taaagaaaag atacaacatg cagtaagaga aatactagag
    30001 gcaattggag aagacccaga tagagaaggt ctaatcgaga ctccaaatag agttgctagg
    30061 atgtatgaag agatattctc tggtcttagt gaagaaccaa gagaccattt aaaagttctt
    30121 tttgcagatg aaaaacatga agaattagta ttggtaaaag atattccatt ttattcatgt
    30181 tgtgagcatc atctagttcc tttctttgga aaagctcata ttgcttattt accaaaagga
    30241 ggaagactta cagggctttc taaacttgct agagtaatag atacattggc aaaaagacca
    30301 caattacaag aaagaatcac taaaaatgct gcagatataa taatggaaga attacaacct
    30361 tatggtgtct tagtagtagt agaagctgaa catatgtgta tgacaatgag aggtgtaaaa
    30421 aaaccaggtt caaaaactgt tacatcagca gtgagaggaa tatttgaaaa ggacattgcg
    30481 tctagagccg aggctatgag tttgattact atgaagtagc aatttattat agatataatc
    30541 atttattgag atataaaatt taatttaagg gagtgtcatt aattgtgttt gattatggta
    30601 aaagaactta tataatggga atattaaatg taactccaga tagtttttct gatggaggag
    30661 attttaataa cttggacata gcaatacaac atgcaaaaga tatggttgac caaggtgcag
    30721 atataataga cttaggagga gagtctacac gcccaggtca tagctatgta gactcagacg
    30781 aagagctaag aagagtaatc cctgtaataa aaaaacttaa acaggaattg gagataccaa
    30841 tatcaataga cacttataag gcagatgttg cagaagaagc attaaaatta ggtgtcacta
    30901 tggtaaatga tgtttggggt cttagaaaag ataaaaatat ggcttctgta ataggaaaat
    30961 atgatgcaga agtgtgtata atgcataatc aagatgggac aaactatgac aaagatataa
    31021 tggagtcaat aaaagacttt tttaaggtaa gtatagaaat ggcaatgagt tgtggtgtaa
    31081 aaaaagaaaa aatagtactt gacccaggcg taggatttgg caaggatttt gaacaaaata
    31141 ttgaagtatt gagaagatta aatgaattaa aagatttagg gtatcctatt ttgcttggga
    31201 catccagaaa atcagtaata ggaaaagtac ttccagttga gcctaaaaaa agattagaag
    31261 gtacaatagc tactactgtt cttggtataa gagatggcgt agatatagtt agagtacatg
    31321 atgtttatga aaatttaatg gcagctagaa tgactgatgc aatatataga aagtaggtat
    31381 aatataatgg ataaaatatt acttagtaat ctaggattct atggatatca tggtgttctt
    31441 aaagaagaaa attttctagg tcagaaattc tttgtcgaca tggaacttta tattgattca
    31501 agagaagcag gtcttagtga cgatataaat aaatctgtaa gctatgccga ggtttacaat
    31561 gttgttaaag atattactga aaataaacaa tttaatcttt tggaggcttt agcggaaaat
    31621 attgctgaag aagtcttgaa taaatttata cttataaatg gagttatggt cagagttaga
    31681 aagcctgagg ctcctgtaaa tggtatttat gactattttg gtgttgagat aaggagaaca
    31741 agagatgaat aaggcttatt tgggaatagg tactaacatg ggtgatagat ttgataattt
    31801 atcaagagca tgtgaacttt tgaaaaatag tgattctata tataaagtaa aggaatcaag
    31861 tttatatgaa acaaaaccat ggggatatac agaacaagca gattttctaa atatgtgtgt
    31921 agaaatagaa acagaatttg aaccttatga gttgttagaa tattgtcaag aaatagagag
    31981 agaactacac agagagagaa tagttcattg gggaccaaga actatagatg tagacatact
    32041 attttttaat gatgtagctt ccactgatga aagactaaca atacctcatc cgaggattca
    32101 agatagagct ttcgttttga taccacttat ggatttaaat gaagaactta taataaatga
    32161 aaaaacagta aaagaacatt taaacctcct atctgctgaa gaaagagaag aagtaaagga
    32221 gcttgtaggt tatgaaagaa aacctattta ataataattc aaagatagag ataaatacaa
    32281 ataacaaaaa gataactgta aaaaaagata aacttataat agctggacca tgtgcaatag
    32341 agagttatga gcaacttttg gagactgcta aatttgtaaa aagtcaggga gcaaatattt
    32401 taagaggagg agcgtacaag ccaagaacat cgccaaattc atttcaagga ttaaaaaaag
    32461 aaggtcttaa aatattaaaa gcagttaaag acgaagttgg tatggctgtt attacagaac
    32521 ttatggatgt aagagatatc gacgaactgt atagtataag tgatataatt caaattggtt
    32581 caagaaatat gcaaaacttt actcttttaa gtgaagtggg aaaacaaaat aaacctgtta
    32641 tgttaaaaag aggaatagca tccacaatta ctgaatggat aggtgcttct gaatatatag
    32701 caatagaagg aaatagtaac attataatgt gtgagagagg tataagaacg tacaatgatt
    32761 atactagaaa tacattagat ttagctgcgg tacccattat tcaaaaggaa acaggtcttc
    32821 ctgttgtggt agacccaagt catgccactg gagttagata tttggtaaaa cctatgtcac
    32881 tggcatcttt tgcatgtgga gcagatggaa taatggtaga agtacatcct gacccagaaa
    32941 atgctttgtc agatggtgct caatctcttt gttttaatga atttgaagat ttaatgaaat
    33001 caattaataa ttattaaaag aggcaagagc ctctttttta ttcgtaatca ttgctaaggt
    33061 aaatttataa gttataattt gatagttaga ttatttaata taaataaaga tttaatattg
    33121 atagaattaa tataaaaaat aaaaattttt tgattaataa gaaggatatc aataaaaaaa
    33181 gtcgaattgt gtatattgag tgattgacaa atttagaata tagtgtagaa tagaaatgtt
    33241 aacacaaaaa attacaccag aaggtgataa tatgaatgat ataaaagaca ttattgaaga
    33301 aataaaagct agatgcgata tagcaagtat aatatctgaa tatatgaata taaaacaatc
    33361 tggagctaat tacaaagggt tatgtccatt tcatggtgaa aagacacctt ctttttatat
    33421 aaatacatca aaacagattt ataagtgttt tggttgtggt gaaggtggag acgtaataaa
    33481 ttttgtcatg aaaatggaaa atttggattt tatggatgct gtaaaaattt tagcaaataa
    33541 atgcggtata gaaattaaca ctaacatgaa tgaagaaact aggattaaaa tagaaaaatc
    33601 taagaaattt caagatatcc atacggaagc agctagattt tatctttcaa acttattggg
    33661 aagcaaaaat cttgggtatg aatatttaag aataagagga ctagatgata aaattattaa
    33721 gaaatttggt ttaggatttt ctttggattc atggaattca cttatgaata ctctaataag
    33781 taaaggatac aaaaaacaag acttattgga ttgcggtcta attgcaaaaa atagagatgg
    33841 aactaattgc tatgataaat ttagaaatag agttatgttt cctatatttg actatagagg
    33901 aaacataata ggatttgggg gaagagtatt agatgattct ttgccaaaat acttaaattc
    33961 tccagacaca ttaattttta ataaaaaaca gaacttatac ggattaaatt ttgctagaaa
    34021 aaatttagaa agtaaaacta tagtcttagt tgaaggatat atggatttaa tttcgcttta
    34081 tcagtatggt ataaaaaatg tagtagcaac ccttggaaca gccttgactg aacaacaagg
    34141 cattttaata aagagatatg cggacactgc tattatatct tatgattctg atgaagcagg
    34201 aataaaagcg actttaagag ctatagatat acttactaaa ttaggtatca atgtaaaagt
    34261 gttagactta aaagatgcta aagacccaga tgaatttgta agaaaatacg gacttagtga
    34321 ttataaaaaa gctatggatg tttctactca ctacataaaa tataaaatag atcatcttaa
    34381 aaaagaattt aacattcaaa aagatgaaga acgagtgaag ttcgcaaaag aagcttctaa
    34441 aattataaaa caattgacaa gtcctgttga aattgatttt tatacaaagt atttaagcaa
    34501 tcaaatagat attaatgtcg agtctataaa gagagaagtt tatggcaaaa attacaataa
    34561 gccatataat aacaaaaatc aaaagaaaat agaagaaaaa gtaattgaaa aagtcgaagt
    34621 cagacaagac ggaaaacaat tagttgaaga aactctaata aaaataatgt tagaagacaa
    34681 aaaaattaga gaaatagcgt tacttaaagt agaagaaagt gattttttat tgaaagaaag
    34741 taaagaaatt ttaaattaca tgattaaaaa tcaagaattg gacaaaataa ctattgacaa
    34801 attgaaaagt ttaaacatat ccgaagaata cttaaaagaa ttaaattcaa tttctttgaa
    34861 tagtataaac ttagagaaca caaaagaaat agaaggaata ataacaaata tcagaaaaaa
    34921 ctcattagaa gagcaaatta atagcttgtt gagagaacaa caagaattag aaaataataa
    34981 tgatatgaaa gaggtagatg gtagagttat ggaaattgct ttaaaaatag ttgagataaa
    35041 taaaatttta aagagcttgt agagaaagga ggtttgagtg tggaaaataa atcgaataaa
    35101 aaagagttaa aaaaggttac tgctaagaca ttaatagaaa aaggaaaaaa gcaaggttct
    35161 ctgacacttg cagagataat ggaagctttt tcggagactg aacttgataa ggatcaagta
    35221 gaaaatcttt atgagacttt aggaaatttg ggaatagaaa taacagaaac aaaaaattat
    35281 aaagctgata tagatttttc ggttgctgat gacgatttaa gtataggcca cttagatgaa
    35341 gatgcagagg caatttcaca tgatgactct tctgcaatag aaatagaaac tgtggattta
    35401 tctttaccaa aagggataag tatagatgac cctgtaagaa tgtacttaaa agaaatagga
    35461 aaaattcctc tacttaaacc acatgaagaa gtagaatttg ctagaaggat gcacgaaggt
    35521 gatgagatag caaaacaaag gttagttgaa gcaaacttaa gactagttgt aagtatagca
    35581 aaaagatatg taggaagagg tatgcttttc ttggatttaa tacaagaggg aaatttaggt
    35641 cttataaaag cagtcgaaaa atttgactat acaaaaggat ataagtttag tacttatgca
    35701 acatggtgga taagacaagc tataacacgt gctattgcag accaagctag aactataaga
    35761 ataccagttc atatggtaga gactataaat aagctaataa gagtatcaag acaactactt
    35821 caagaacttg gaagagatcc aaaaccagaa gaaattgcaa aagaaatgga aatgacagaa
    35881 gataaagtaa gagaaataat gaaaatagct caagaccctg tgtctttaga aacaccaata
    35941 ggagaagaag aagatagcca tttaggtgat tttattccag atgatgatgc tccagcccca
    36001 gcagaggcag cagcatattc tttattaaaa gaacaaatag aagatgtact tggttcgtta
    36061 aatgatagag aacaaaaagt attaaagctt agatttggtc ttgaggatgg tagagccaga
    36121 actcttgagg aagttggaaa agagtttgat gtaactagag agagaataag acagatagaa
    36181 gcaaaagcac taagaaaact aagacatcca agtagatcaa aaaaacttag agattattta
    36241 gactaaaaag atacatcatt gatgtttttg tgataaatgc catgagataa gtgatatctc
    36301 atggctattt tgtagtaaag atttaatttt atttttgtag ttatttcagt ctaatatcta
    36361 taacttggat taaatcctat aaataaaggg aattgaaagg agaattatat ttgaaattaa
    36421 cagatagatt attgaaaata gcatcattag tgtcagatgg taaaaaaata gctgatatag
    36481 ggacggacca cggatacata ccagtatatt tgttaaaaga gggaaaagta ccatttgcag
    36541 tgctagcaga tgttaataaa ggacctcttg acaatgcaca taaagaagtc atacagaaca
    36601 atcttttaga taaagttgat ttacgattgg gttctggtat agagatactt gaaatagggg
    36661 aagtagaaga agtgataatt gctggtatgg gtggaatctt gataagtgag cttctcgagg
    36721 ctaaaaaaga agtagcacat aatgtagaaa aattaatatt acagccaatg caagcacaag
    36781 aagaacttag atattacctt ttaaacaacg gatatgaaat tttagaagaa gttttagtga
    36841 gagaagattt tagaatatat gagataattg ttgccaaata tacaggtaaa aatactataa
    36901 tagaagatga gatatattat gaggttggaa taaagctttt agaaaacaaa gattctcttt
    36961 ttaatgattt tatagaaaaa aagataaaga catatagttc tatagttaat aaattagaag
    37021 ggaaaaatgg ggaagctata gataagaaga gaaaggaaag cgaagttgca ataaaaaaac
    37081 ttgaaaattt aataaaataa ataggaggta tatatgctat taaagagtct aactagaaaa
    37141 attgaaaaaa agtatcctct aaacttagca gaggattggg ataatgtagg tcttatagtt
    37201 ggagattttg atatggatgt aaaaaaggta ttggtatctt tagaagctaa tgaagatgtt
    37261 attgatgaag ctatatccaa aaatatagat ttaattgtga cacatcatcc ttttatattt
    37321 gggaaaatta ataaaattaa tagtggagat ttaaaaggca gacttatcca aaaacttatt
    37381 aaaaatgata tatcacttta ttctatgcat acgaattttg atatagcatt tgatggtcta
    37441 aatgactatt ttatggaaat tatggaattt ggtaattcaa aggttttaga tataactaaa
    37501 agcgaaaatt tgtataaatt agcagtatac gttccacata actattcaga tgaacttaga
    37561 aaggttttaa gtaattcagg agcaggtcat atagggaatt atagtgattg tacgttttca
    37621 atagaaggtg aaggacaatt taagccatta gaaggctcta atccgtttct tggaagtgta
    37681 aatgatatag aaactgtaaa tgaagttaaa attgaaactg tagtaccaca gaagctttta
    37741 ggtggggtaa taagttctat gttagatgca catccttatg aagaagttgc atatgatttg
    37801 tacaagttag aaaataaagg tgagatattt ggactaggta gaataagtaa acttgataaa
    37861 agtatgacat tagaaagtct ttcaaggaaa ataaaagaga aattaaatat gaaacacata
    37921 agagtagttg gaaaccttag tacagacata acgaaagtag ccgttgtaac aggagctggt
    37981 tcagaatttg taaaaaaagc taagagacaa ggtgcagaag tactaattac gggtgatgta
    38041 aagtatcatg aggcacaaga tgcacttgat attggaatgt gtatagtgga ttgtggtcat
    38101 tttgatacag aagatatatt caaaaatgtt atgaagagat ttttagatga atttagtgaa
    38161 attgaagtaa taaagagtaa tgtatatttg aatccattta gtactattta gaagtgtttg
    38221 attaaaaaat actatataaa aaataaattt gagtttaatt agggggataa tgatgaaagt
    38281 agcagtaatt tttcatagtg tttgtgggag tacatattta ttagctagag aatataaaga
    38341 agtgcttgaa gaaatgaata tcgaggtaga tatatttaga gtaagtgacg aagttgcaaa
    38401 aacacttcct caatattatt tgataaatta caaagaatac aaagacgaat ttgaaagtat
    38461 aaatgtaatt aaatctggaa aagaaatatt agattatgat gctatattta tgggttcacc
    38521 aacatattat ggaaatgtat ctggaccaat gaagatgttt atggatagtt tttctgatat
    38581 ttgggtaggt gctcctttga gtggtaaaat atttggttgt tttgctacag caggttcaca
    38641 acatggagga ggagaattag ctttgcaagc tatgaatata tttgctcaac atatgggaat
    38701 gactcttttg tcagttccat gttcagtaag aggaggttat ccagcgtatg gaatacttca
    38761 tatagcagga gataattctg atataagacc aaatgatgat gccaagatag gtataagaga
    38821 ttacctaaaa agacttaaca tataagaata tcatataaaa atacctaaaa gtagctgtat
    38881 atacttttag gtatttttac ttaattatat acgtgaagct ttaccagaaa tatggtcaat
    38941 ttctatttta acaacagttg ttaagttcat atccttctct atgtacttca tgccttcttc
    39001 aaagaatcct ttagaatatt tttttattat ttctacaaga gcatttttct tttcttcatt
    39061 ttctacagtg caagcttttc caaaaactat agcactagaa taagtagtac taaatttatc
    39121 tggaataaca ctttcattag caactactaa aaaagaaact ttgttgtttt tcgatatatt
    39181 atctaactta tgtccatttc ttgcacaatg aaagtaaata gaatcattaa agtatacata
    39241 atttacagca actccataag gataaccatt ttcagatata gtggaaaaag taccaaattc
    39301 accatttttt aatacttcaa cagtatcttc ttttgtcatt tctctttttt tcaatctcat
    39361 ttctttaaac ataatatcat cctttctaat tttgatgctt aaattaaatt ttagcacatt
    39421 tataaagatt atgctatgtt ttttacaaat tttaagaaaa aaatatagtt taagataaaa
    39481 ggtagtgaaa gagaagctat ttggaggttt atttatgata ttattgttag agtagtacaa
    39541 acaatactaa taaatttaat agctggtttc ttgttattta aggtagtaag catgtctata
    39601 agaaggggaa gttatcgagg gtagaagttg ttatttataa cgatattata aagaaaatat
    39661 tattatataa aataataaat agtaaagagg tatcaagttg aatataatac ttaatacctc
    39721 ttcaaaatta aattataaaa gtgttgtggg aattgtccta tacatggtaa ggagataata
    39781 aagaatgtat ctttaaagtc tcaactaaac agcaaaattt atccaacaaa catacaataa
    39841 atgcttcttt gtatctaggt ggcttaacag taagtggcca catgtgtttt aaaattatgt
    39901 ccgtttcttt ttcatttatt tgaaaaaata aagttgcatt ttttaatgct tctctagggt
    39961 gagtaaatcc atgtaatcct tttctatcac ctttgtaatg ccaatcataa agaaaaaagt
    40021 cgtgtagtaa agctcctcta ataacacttt gaatatcaac acgtaagtgc aattttttac
    40081 ataatagata actataatat gctactgaca aactatgttc aagacatgaa acattgccat
    40141 gatgaggaaa tgttctcata agttgaactt tttcagaaga aagtatctca gaagcacatt
    40201 cattaaaata tttgatttca gcttttgaca acattatgaa aatctccatt cttagtaata
    40261 tataaatact atacttcaac gataatatga aatatttctt atcctacaaa atataatacc
    40321 caataataca agtaagatac cttttatggt attttaaagt aagagagatt ttattaggct
    40381 aaacaatgaa aaaattaaaa gtaaagctat agcaatatat agtatttttc caagaggatt
    40441 gccaaaattt atagtccatc caataccaaa ccttttatta accattaatg atgggtcatt
    40501 tggattatta tacatgatgc ctgctatcca atacttctca tcttcttctg gagaataaga
    40561 tgagttgaat tttaaatttg gggaattaat atatgttgct attaaataaa ttataactaa
    40621 aagcgttgta atattcatag cagttgatag ttttgttttt attgataaaa gagtagtaaa
    40681 aaactgtgtt gtcattataa tcatcaatat taaaaacaaa taaccaattt tatttaaata
    40741 tttaatgttt tcaactctac tttcttcaat tctatttgta tctatcttaa tccttgactt
    40801 tatggatcca atggaagtta tatataataa aaccattaaa caaaagtcag taccgattaa
    40861 tttaaataca ttaagaaatg atttatctat aaaaacatca ggagacccat ttatgttcca
    40921 atgagtggca attgagtctg gcaatttatt ataattaaat gctataaaaa tactcatccc
    40981 caaagtaaat agtatcggta ttaaatagat tattttaaat ttttttatta ttttattttt
    41041 cttatttata aaatccatat ctactattaa ttttgaatct acatctatat gacctaattt
    41101 agaataaatt tctgatttaa gcttcttagc ttttttatgt gtatgaatat atagtatact
    41161 ctcatataat aaaaaaccta taataccaat aaaatatgaa agttccaatt tattaaatgt
    41221 aaaaaccaga ataaaaacta atataaagtc tataataaaa cctaaagata atagtttttt
    41281 aaattcttta tctaatttta taaagtaatt ataattttta tgctcttggt ctatagaaac
    41341 tccatagatg tgttttttac ctacaaaata gggcataaaa taaaatgtag catacatcaa
    41401 aattagaact ggaaatattg taaatagaca ttcaatctta ctcataatat ttcacctcat
    41461 acttgtcaaa taaacttgaa cttagtgaca aaaattcttc tttactaata cctgataaat
    41521 aagattttgc caccaataat tccaagtcaa gtttattttt ttgacgagtt gtattatcta
    41581 ttttcattgg tagttgagct acaatagcac cttttcttct atcaatattt aagaatccct
    41641 cttcttttaa ctcattgtag gatttgttca ctgtatgtaa atttacacca atattttctg
    41701 ccatacttct tacagatgga agtgattcat ttattttcaa ttctcctgaa gctatagcct
    41761 tagttatttc ttctttaatt tgtacataaa tagatttatc actattaaaa tctaaattta
    41821 aaaccataaa aaacctccat tatgctttat aaatgaaaac gattgttata tacatagtat
    41881 aacataaaaa ataataacaa acacaaaata taagtttata ttttgtaaaa attgtaattt
    41941 aaaaaataac ataattttta ttaaaataat acagatacta tttatagata gaaataaaaa
    42001 ttagaaagga gaaaaaatat gttaacatat ttaatgaaaa gacaaatgca taaaaaagat
    42061 gatggaatga gtaaaccaat gatgattaca ggagctgtaa ttacaggtgt aggagcatat
    42121 gctgtataca aaatggtaaa aagccataaa tctaattctc aaatggtcaa tacaaattat
    42181 tatggaaata gcgattatga tgattataaa tatgacgaat ttgattatga ctgtgattgt
    42241 agagacacaa aacaagatta tgaatatgaa gaattaaaaa aaaaagtaaa agaatttaat
    42301 tcaagaagaa taaattgtga aaattgtcca catgtttctc aagaagaaat gatgcaatat
    42361 gtaaatagtg ttaaagatgt aaaggaagat attgatttac atgaagatgc taaaaaagat
    42421 aatatttaca aagaagatga atacaaaaaa tatgaagaag aataagtaat attttgtata
    42481 actgaacaaa tagtaatgtc aaattattta atatctagtt ttaatatgta agttgtaact
    42541 taacttgaaa gaatcagtat cattctttag atagttaagt tacaacttac attttgtttt
    42601 tataaatttt aatagttctt tgtgactatt ttgtaatttt agaaatattt tagtatccag
    42661 ggtaattgtg tataataaaa cttgtataga tagatagtat gaaattaagc agatagttta
    42721 aaattaaaat gaaaagaaag gaaatagtta tgttaaagtt gttgatagtt gaagatgata
    42781 gtactatatc ttttggaata aagtatgctt tagaacaaga aggatttagt atagatatat
    42841 caaaggattt atctagtgga aaagaaatga tttcttctaa tgaatatagc atgatactgt
    42901 tggatgttac attgccagat ggaactggtt atgagctttg taaatatata agaggattct
    42961 ctcaggttcc tataatattc ttgactgctt gtgatgaaga agtaaatatt gtaatgggtc
    43021 tcgatatagg tggagatgat tatataacaa aaccttttag aattagagaa ttaatatcca
    43081 gaataaaagc tgttttaaga agaaaaggta atacttcaga agaaaataag aaaatactta
    43141 aatttggaga tttaagtata tatacattag aagctagagt atataaaaat gataaagaaa
    43201 tatttctgac atcagttgaa tataaacttc ttttaattct tatacagaat aaaaatactg
    43261 ttttaagtag aactcaaata ttggaaaaac tttgggatgt aacttatgat tttgtaaacg
    43321 acaatactct aactgtttat ataaaaaggc ttagagaaaa aataggtgat gatttatgtg
    43381 aaccaatcta catagaaact gtaaggggga ttggttataa atggatagga agtgaaaata
    43441 gtgtttctat ataatccaga agtgaagaag tttttaagta agtatgttac tttgatgttt
    43501 attgttatca taatatctat tggatttagc ataatcaacg tgtctttaac taaagagatg
    43561 gttgtaagaa ataatcaagc tataataggg actttatcga gtaagtatcc aaacttagaa
    43621 agtcagatag tagacataat aactcaaggg aagtctatga agaacataga ttatggtcag
    43681 aaaatattaa gtaagtataa ttatgataaa tctattaaga taaactctga gcctattatt
    43741 tctaaattag ttttagagac tatcaaaata aatataatat tagtatgtat aatatttatt
    43801 ttgatatttg tgttggttgt tagatatttt acgtcaattt acaatgattt atcagatatg
    43861 actaagtatg tttactatag ttcagagggt aagccatttg atatgaaaaa caagaatcaa
    43921 gaagggcaga taggtcttct aaaaactgaa ctcttaaaga tgacgacaat tcttaatgaa
    43981 aaggttgaac ttttaaaaag agaaaagata tttttaaaca atacaatttc cgatatatca
    44041 catcaattaa aaactcctat gacttcttta ataatgttga atgatttatt atataatgat
    44101 gtaccatacg aagtaaaaat cgatttttta aataagataa aaaatcaatt aaatagaatg
    44161 gattggttga ttaaaagcat gcttaaatta tcaaaggtag aagcaaaagt gataaatttt
    44221 aaaaaagata aggtaaaatt tagtgaactc atacatagag caatgctatc tatgaaaata
    44281 cctatggaga ttaaaaatca aaaactgact atagagggaa atgataatgt atcttatatt
    44341 ggtgatattg attggtctgt ggaagcacta gtgaatataa tcaaaaattg tgtagaacat
    44401 actcctgaat ttggaaatat aattataacc tataaagaaa atccattatt ttctgaacta
    44461 ataataaaag atgagggtga aggtatagat aaaaaagata taccacatgt atttaaacga
    44521 ttctatagag gaagaagtag ttcaaaagaa gatagtgtag gaataggtct tgcaatgtca
    44581 aaatctataa tagaaagcca aaatggcgat atatatgtaa acagcgaaaa aggtaagggt
    44641 acagaatttc atataatatt tcataaaatg tatgatagtg actaatctgt aatatttaat
    44701 tcactttata gtaatagcca aaacctaata tatgaagtat agaatataaa tattggaggt
    44761 agttatggaa attttaagag tagaaaatct aactaaaagt tatggtaaaa atgaaacaaa
    44821 agttgatgct ataaaaaatg taagtttatc agttgaaaaa ggaacgttta tagcaataac
    44881 aggtccaagt ggaagtggta aaagtacctt attacattta ttaggaggag ttgacagacc
    44941 aactagtggt aaggtttata taaatgatgt tgatatatat aatttaaaaa ctaaggattt
    45001 ggcgatattt agaagaagaa atataggtct tatatatcaa ttttacaact taattccagt
    45061 cttaaatgtg aaggaaaaca tattgcttcc agcagagctt gacaatagag atattgatag
    45121 agaatatttt gatgatttaa tgaaaacatt aggtctaatt gatagagaaa agcaccttcc
    45181 aaaccaatta tcaggaggtc aacaacagag aacctctata ggacgtgcat taattaatag
    45241 accttctata atattagcag atgagccaac aggtaattta gatagtaaaa attcaaagga
    45301 aatattagaa ttgttaaaat tgtcagtaaa aaaatacaat cagacactaa taatgataac
    45361 tcatgacaaa aatatggcac ttcaagctga tagaattata agcatagaag atggaatcat
    45421 aaaaagtgat gaggtgatgt agatgaattt atatacatca ctaaccatta gatacttaaa
    45481 acaaaataaa agaagaacca ttgtaaccat aatcggtata atactttcaa cagctttaat
    45541 ttgtggtata ggaaatatat ttgaaagttt tatggattat caaatgagag aaactataaa
    45601 gaatgatgga agtttccatg ttacatttta tgatgtaaat agaaaaaatg tggaatatgt
    45661 aacgaaatca gctgaaatag aaaaacatgc atttaccaaa caacttggat attctaaatt
    45721 agaaaatagt gaaaatgcta tattaagtat aaagcaatat gatcaaaatg caataaacgg
    45781 atataaagtt tctataaaag aaggtagatt tccagctaag gaaggagaaa ttgttttaag
    45841 tgaaagtatt attaatctta tagatgataa gttaaaaata ggagataaga taactttaaa
    45901 agtaggggat atgtttgact caagcaagaa aaagattgat agtatgacat ttcatgaagg
    45961 tgattatata gcaaatgaaa aagatagaac ttttaaagtt gttggtataa ttaaaaaacc
    46021 tgggtttgaa cgttataatg gaattgcaac agctatagcc tactttaatc ctatgaataa
    46081 ttacaatgat acaattaatg tatcagtagc agtaagaaat cctaaagatg tgtataagat
    46141 aagtaataaa ataagtaaaa atatatattc aaataaagat aaagaagcag tttctgatat
    46201 gataaaatac aatgaacatt tattgaggtt acaaggtgct agtaagtatt caaatataaa
    46261 tagctctata aagtctataa ttatagcagt aactatttta gtaatcatat gtacaattgc
    46321 tacagtgtac aattccttta gtatttctat aaatgaacga aaaaaacagt ttgggatatt
    46381 aaattctata ggtgctacat ctagtcaaat taaaagatta gtttttatag aaggtattat
    46441 aattagttta attggtatac caataggact aatatctgga acagtagcta tagacctatt
    46501 gtttaaaatt ataaataagt attttactga atcggttgtt actaagatga gtttgcagat
    46561 agtgtataat ccaataataa ttattgttag tataataata gttttgctta caatctttat
    46621 atcaattcta ctacctgcaa tatcggcttc taatatttct ccccttaatg tgattaaaaa
    46681 tactggagag tataaagtgg gcaaaatcaa aagctcaaga cttattaaaa tgatttttaa
    46741 aactgaagga gtacttgcat ataaaaatat taggagaaat agaaaaaaat ttataataac
    46801 tcttttttct ttaatggtaa gtataataat atttatatct tttagtggct ttacattact
    46861 tttactaaga ggtgaagaaa ttagaaattc tcaaagaaaa tatgatttgt atttaactgc
    46921 aaagaacaca gctaggtctg tagaggatac tataagtgaa ctagaagata ttgatgggat
    46981 aaaaaacttt gaattggcaa caggacaata tgtgtctata agagtaagtg aaaataaaat
    47041 aaataaatcc aaggaagatt taatcaggaa atattatcaa aaatataaga ttggagaaag
    47101 ttatgaatat gatttcagta ataatgaatt gatttttccg ggagattttg cagtaaaaaa
    47161 caaaataaat aacttagtac agggctcttt taataaagag agagcaattg aagaaaatgg
    47221 tgttatatta gttagaaaaa gtgcaattga agaaaatggg aagaaaggtg tagtagaact
    47281 taccaactat aaagtaggag atacagtaaa ttgtgaatat cttgatgaaa atgccttaag
    47341 taaaaaagta aaggtcaaga ttcttgctat aactgatgaa gaacgtctag gttttggtta
    47401 tcaaaatatg gggttacaat ttataactta tgatgaagtt gctaaaaatt taaatttaaa
    47461 attaagtaaa agccttatat ttattgattc aggaggaagc attaagacta agaaggaaat
    47521 agaagctttg gcaaataaaa atgattttaa cttttatgat gaaatttcaa gcagtgaaag
    47581 tgaaaaacaa gatttaaagg ttattaaaat atttgtatat ggttttatag tagtgatatc
    47641 tttagtgagt gttacaaata ttctaaatac agtaagtaca agtataaatc taagaaaaag
    47701 agaacttgca gtaatacaat ctataggggt tactcctaaa ggatttagga aaatgatata
    47761 tttagaaagt tttatatatg gtatactgtc attgttgttt ggaataccaa ttagtattgg
    47821 tataattcta attatgaata aacttatttc aggtgtaatt gaattttctc cgattatacc
    47881 gtggacagcc atagttatct gtatagtaag tgtttttata ataactttta tagcagggta
    47941 tataccaatg agtaaattaa ataaagaaaa tataatagat aatataagaa gagaaagtat
    48001 atagatataa aaataattct taactatata aaatattatt aaaatcattt aagtggtata
    48061 aaatattatt atatcactta aatgattttt tatttatata agaaatctaa taataaatta
    48121 ctagaggtat ttaactattt agaaagaatt ggtattatat aaagtaagag aatatataat
    48181 aagaaagaat atttgatttt atttgaaaac aaaagaaaaa gaaggtgatt actatttctc
    48241 atataactgc gaagaatatg tataaaagtt tagaggaaag aataaacaag tttccacaag
    48301 gtgctccacc atctgataca ttatacaaaa tactaaatgt actatataca gaacaagagg
    48361 cgaagttagt tgctcagctt ccaataaagc ctttcagagt aaaaacagca gctaaaattt
    48421 ggagtgtaag tgaaagtgaa gcatatagag tattggataa acttgctagt aaggctctga
    48481 tactagatat agaagataat aaagggaaga aatatataat gcctcctcca atggctggtt
    48541 tttttgagtt tgccatgatg agaacgagac acgatataga ccaaaaactt ttggcagaac
    48601 tttactatca atatatgaat gtagaagaag attttatcaa agatttattt tattcaacag
    48661 aaacgaagct tggaagagta tacgttcaag aggaagtttt aactaatgat aatgaggtta
    48721 gtattttaga ttatgaaagg gctactcata taattgatga atcaactcat ataggtataa
    48781 gtatgtgtta ctgtagacat agaatgcaac atgttggaaa agcttgtgat gctcccatgg
    48841 atatatgtat gacgtttgac aatgtagcaa attctttaat aaataataaa tttgcaagac
    48901 gtgtggataa aatagaatgt aaagaactac ttcatcaagc atatgaacat aacttagttc
    48961 aatgtggaga aaatgttagg aaaggggtta cgtttatatg taattgctgt ggatgttgct
    49021 gtgaagcaat ggtagcagct aaaagatttg gaaatcttca tccagtacag acaacaagtt
    49081 ttataccaaa tataaaccat gaaaattgtg taaagtgtgg taaatgtata actgcatgtc
    49141 caatagatgc gataagcaag gttaaggaag atggtaaaga atatataaaa attgatgagg
    49201 atagatgttt aggttgtgga gtttgtgtta gaaattgcca taaaaatagc attatgttat
    49261 taaagagaga tgaaaaaata ataactccag caaattcagt acatagagca gttctcatgg
    49321 caattgaaaa agggcagtta caaaatttaa tttttgataa taatgctctg gctagtcata
    49381 gagctatggg agctatactg tcagctatat taaagcttga accagctaaa aagattttag
    49441 ccagtaaaca attaaagtca gtatatttag ataaattgtt aagtatgaat gataaataga
    49501 aactaactta aaaaaggcaa agttttagac ttatctatat cttaataaac ttatcattta
    49561 atatttaaat ttaattttta cacatataaa acttataact taaataaaaa aaggctatat
    49621 tcaattaata ttacttgaat acagcctttt ttagttatgt taagctattt cttttatttg
    49681 cttaaatgag ttttcatttc catttccacc aatttgtgtt acagatttaa atctcatagt
    49741 tttaaatagt tctttttgat tataatctag tgagtttcct actagcatta caggagattt
    49801 agtttttcca gccaaaactc caacagataa tccgtctatt aaatcatctt gtttattcat
    49861 tccattttta gcaacatata aattgtctat cttagaatcc ttgtaaaatt cttttattac
    49921 ttttgcatta gtttcatttc tagtgttacc tgatattctc tgtggatttt gaagtttact
    49981 ttctatattt ttagaaactg tatattctcc accgattaca taagatttat caatcttttt
    50041 gtttttaaat aagttattta tttcagttat attactattt tcattagtaa gtattatagg
    50101 catatcattt tgagctgata cagctccaat gcttactgca tcggctaatc ctttttcgcc
    50161 attaactact gaaatctttg atatattgct aatattgttc aattctttag caatgttcat
    50221 agaagtttga tatctatcac ttcctgaaat tctagataca gagatattgt ttgattttat
    50281 agtatctaaa gatttttcat ttatagaagc ctctccacca actacatata catttttaac
    50341 ttttaatctc tttaattcag ccaaagtttt ttcatttatt tgagagcttc cagtcaataa
    50401 tataggagcg tttttcttgt atgcaaatgg tgttgcggcc aaagcatctg caattgctga
    50461 atcgtttatt aaaactgcat tttcagcatt ttcccaacct gcttgactta tcttaataga
    50521 agtttcatat ctatcagttc ctgtaagtgc acttgcattt acttcatctt gatatgtaac
    50581 ctcaaatcta gcatttggac ttcctaagaa aacaattacg cctccttttg gcaatctaac
    50641 tctattgttc tttgtaacta aagaatagtt tacaggaaca cctttatcat cataaacagc
    50701 aaaagctgaa ttttgaggaa gattaacttc tattttttta tttgcgatat cgtcaccaat
    50761 cttataccat tttgcataac cattggattc tagttcacaa gtaaaagatt tttctgctgg
    50821 caaattagtt atagaatctt cactaacata cgttagtgtt ccaaaagata aatactctgt
    50881 accattttct ttatgaagtt taatgtcgga taaatcacga cctattacac caggtatttc
    50941 tataaaagca tttgagttat tctcatccat tattttagtg ttaactatat aacctggagt
    51001 ttcatcagaa agactaaaac ttgcttttac agagccaaac atatagcttt gagaagtata
    51061 tttttcatcc actagatagt aacctttgcc acttcttttt ttccacactt ctttgacact
    51121 atttgatata ttgttgtcat ctactttttg agctacatag tataaacttg ctgtctgacc
    51181 taatccaggg acatcatcat aagagctcat atttaaatat gtgatattat ttttttcttt
    51241 tacaaatttt aaacaactgt tacccttttc agatacaaat ctatcttgac ctatgtatac
    51301 gtatttatct tcaggtccat tttctatata aggagaagat actgttaaag taccattatc
    51361 attaacatct acttttatca tatttgaaga agcataaaga ccactatttt cttttagaga
    51421 gctaggcatt ttaacttgtt gtggcttact aaatgtttta tcaggtttta tttctttaat
    51481 tttacctttt tcttttaatg cagatagtaa gatttcttgt ccaattattt cgttaagttg
    51541 actacttcca ccagaagaaa gaactgcaac tgccatattt tcatctggaa gaactataag
    51601 attactgtgg aataataaag agtctccacc ttttgtaaga gcttttaaat tatactgatt
    51661 aaatggataa gtgttgacac aatcccaccc taaaccatat ccaagtatag aatcttctcc
    51721 ttcaggccat agaccattta aatattcttt gttttccata gcttttactg aagcaggaga
    51781 aagaatacca tttgaatttt tcataaatgt ttgtgcaaat gtacatagat tttctgcact
    51841 tgaatataaa ccacctgcac ctatagcatt aaggttatct tgtggaactg catcttccca
    51901 ataaggtaca tatgcttttg ctagttttga actatcaaaa ctattttctg tagtttttgt
    51961 attttgtaag ttaagtggat tatttatgta tttatcaaga aaattagtaa atgacatacc
    52021 agatactctt tctactaaaa tttcagctaa agtaaatcca tcattacaat aaacggaaaa
    52081 agctcctggt ttagctttta atctttgttt ttgtaattct tttaagaaat tatcatgacc
    52141 ataagaatca ttgtctgcta ataaaatagt gtttttaaaa ctacttccca tcaaccctga
    52201 tgaatgattt aataacattc ttggagtgat ttccttgtat ctatcatcag ccattttaaa
    52261 ttcaggtata tactttacaa caggagtatc taaatttaat tttccatcat caaccaactt
    52321 cataacagct gttgtagtaa acattttact gatagatgcg atactataca tattatcctt
    52381 atttaagttt ttgttatcct gtttgctgta aactccacca ttaccagaaa tctcaatttt
    52441 gccattatca atcaaagcat attgagcact tacagcacca tactttgata gcaaagtttg
    52501 gattttctct ttagcaagag ctttagtttt tgtgtaagat tccgcgtttt tactataatc
    52561 atgtaattct atatcagaac tttgatattt ttcggaatta tcttttgtat tatcagcaaa
    52621 agtaatattt ggagcagcag taaataacat actcaatact aatgtactag ataataattt
    52681 agagatcctt tgcttaaaca tattacatta cctctttccc tttttaataa tttataatta
    52741 gcataacatt cttaattatt ttaatcaaca gattattatc aataaaaaaa gcttttataa
    52801 gtatagcttt ttatataaca gagaaaaata taaaaataat atttgttgtt gtataaagaa
    52861 taaagggtat aggtaatata taaataaaat ggaggaattt tagacatatg tataagaata
    52921 taaataagaa gcaacttaaa gaaatgatga aaaatgaaaa ggatgtttta ttattagatg
    52981 taagaactaa agatgaattt aaggaatata aaatagaaaa tgctataaat atatctttac
    53041 aagatttaat caataatata gatgaaattt acgattataa agataagaaa gtagtagttt
    53101 attgcagaag tggtcataga agtgttactg catgtaattt gttagctgaa gaaggttttg
    53161 agcatttata taatttaaat tcaggaataa ttgattatat gagttaaata aggtaagtta
    53221 tacattaaat actatgtata gctctgttta ttaagtagga atatatctaa atatttataa
    53281 gataaattta ggaaagaacg aattttttcg cttttttcta tgacagtttt tgtagtaaat
    53341 attagttttt aagttggaaa aaggtagtag ctttttagct actacctttt aatatgaact
    53401 tagaatatta ttaaaaaaat atatttaaag acagaattaa ttttttaatg accagttaaa
    53461 ttactatcgc caaatttatc attaaatggt tttataactc tatttatagg tccttttaga
    53521 agtacgttta aacaaataga cagaatcata aatagtaata gaactagtat atctttagtt
    53581 agatttggag catatatacc accaactgct tcccttgtag cacctattgc ataggtaaat
    53641 ggcattatag ggtttattct ttggaagaat gtaggtgtaa cttgtatagg gaatgtacca
    53701 ccagaagaac caatctgaac gactaatagt actattgcaa ttgcttttcc tacatttcca
    53761 aatacagaaa ctaaagaata cactataaag ttaaatacca tactagtaaa cataagcaga
    53821 actatcaata aaattggatg ttttgctgtt actcctaaca ataatatatc tccagttcct
    53881 attataaaac cttggacaag agctatactt aaaaaagtaa gacctcttcc aaagtaaatt
    53941 tcataaggtt tatagtttcc atgtacagat gtagacaata gtgctgaaat aagtaatata
    54001 ccaacccatg tagaaagaac actataaaat ggtgtcattg cagaaccata attttcaatt
    54061 ggatataatt tctctgtttt cacctcaaca ggttctttta agaaattaga ctttgtcaat
    54121 atatcacttt caagcaagct gactaatttt ttcatatctt caccattact aattttgctt
    54181 aaagtatcaa tcaaatcatc caacattcct tttgctaaag gaagtctttc tcttatcaat
    54241 gatatacttt cctgtgcatt tcctgaaagt tttagagaag tagtaagtat ttcttcaacc
    54301 tttggaagtt ttgcttctgc cttatctaaa acagtaatta tatcatttgc tacttttata
    54361 ctgtttgcaa atatactatt tataggtttt gatatttttg agtcaaaatt atttaaaata
    54421 tttaaattaa ttcttccaat accatttgat agacttaaaa cattattcaa agcacttata
    54481 gatggttgtt gtccagatat aactttgttt ttaatatcat ttaatgttga tatagatgaa
    54541 tctattttat tgctagagtc ttcaagatta tctattacat catccaatct attatttgat
    54601 gtaagttggt ttaatttagt taaaaagtcc accaaagtat cgtttaaaga ttgcaaatta
    54661 gaaagttttt ctgataaatt atctatcaac ttaggtacat cttcactgcc actatttact
    54721 gcatcaatta aatttaatgt aagagaagaa gcagaagatg aaaggtcaac cattaaattt
    54781 aagtcagact taataagagg agaaagttcg tctaaattat catttgtatc ctctaagaat
    54841 ttttttaagt cacttgataa tagttttgta tcattcagag tctttttaat tgtaggtaaa
    54901 tcagatttaa tatctttaac tgtatcagat aattttgaag tagcatcaga agctaaatcc
    54961 acagtcttat ttatatggtc aaatctcttt tgaaggtcaa taagggaatt ttcaactttt
    55021 gtcaattttg gaagactgtg ttcaattcct gcaccaactc cgtttgatat accaagaacg
    55081 atttcactaa ctgtttttac tatagtctga ttaacctgta gttgtattgt agaagcacct
    55141 ttatctgtaa tctttggtgc aactgcattt attttttcat taacagtata gataatttcg
    55201 ccttttttaa catcatctgt aattaaagat gtcaaatctt ttgtaaaatt ttttggaatc
    55261 ttaagtgatg cataataagt acctttttta acaccttcaa gagcagtttt ttcatctaca
    55321 aactgccaac ctaaactctt gttatctttg agttgttcaa ttaattggtc tcctacatta
    55381 atcttttgtc ctgctatttc atttccttta tcttcatttg ttactgctac aagcatatta
    55441 gcagtgcttc cataagggtc ccaagatgcc tttatattga accaagcata cagagatggt
    55501 aaaaaagcaa gacctaaaac tattacaagt acggcataat tgccacgtat atcttttagg
    55561 tcacttttaa aaatttctaa tatatttttt aaaccctttg aaggtcttaa attcttgata
    55621 ttattccagt ttaaaatttc ttttaaacta ttagtttttt tcaaatgtct cacctcctaa
    55681 aatattttga taaagaaaaa agttagattt ataatcaatt ttaaattata ttacttttta
    55741 cacaaatagt aaagttaaaa ttttgtctta attttaatac atatatatta tatataatag
    55801 tatgctataa atatatataa atataggaaa taaaaacaaa taatttataa aatatatggt
    55861 ataaaaatta ataataaatc aaatatttat aattgatata atcaattaaa ttagccatta
    55921 tgatatactt ttggtaatga gaaaattcta tgaagggatg attgaatgaa gtattttaaa
    55981 aaatacataa aaaaatatat agtattattt ctaacagcag tatttttttt aacattggaa
    56041 gctttttgtg atttagctca accaactata atggcaaaaa taatagatat aggggtttca
    56101 aataagaacc tagactacat actatcaaca ggagctataa tgataggtat aactttttta
    56161 ggtgcaatat ttgcaataat aagaagtgta atctcggcaa gagtttctca gcatttttct
    56221 tatgatttaa gacaggatgt atttgaaaag ataaatacat actcattaaa acaaatagat
    56281 aaatttggta gagcttcgtt aataacaaga attactaatg atatcaatca aatgcaacaa
    56341 ttcgttaatg gaatgatgag agtttttata aagtcaccaa taatgtgtat aggaagttta
    56401 attatagcta taaaattaaa tttaaagatg tcaataatta ttctaattgc agttttaatt
    56461 atatttatta taatattgct taatatgaag atagggtata gattatttaa aaatgtacaa
    56521 gaaagtacag ataaagtaaa ttcaaaatta agacagtttt taagtggaat aaaagtagtt
    56581 aaactatttt gtagatacga ttatgagaac caaagctttg aagagttaaa tgatgaactt
    56641 tttaaaaata gtagaaaagc tacaactatg atgtcatttt ttagaccgac aattacaata
    56701 atcattaatg tttccataat aataatatta ctgattggaa ggcatttaat ttattcagga
    56761 gaaattaaaa ttgggattat agttgcttat gtaaactata tgactagaat attaacatct
    56821 cttataatga tttcacatgt ttttaatgtt tttgttaggg caaaagcatc ttatgagaga
    56881 ataagtgagg ttttggttga tgagaatgaa gaagtaattg agagagaaga aagtttagat
    56941 gttggagaaa aagatttaaa gtttgtaaat tgtgatataa tttttgaaaa tgtagatttt
    57001 tcgtataaca aaaatacaga tgaaaaaata ttaaaaaacg tatcctttaa aatagaagaa
    57061 ggtcaaaata ttggtgtgat tggtcaaact ggttcaggaa agacttcttt agtaaattta
    57121 attcaaaaat tatatataat tgataaaggt gatattaaga ttggaggacg tagtatatac
    57181 agtatttctg aagaaagttt aagggaaaaa ataggtgtag tatttcaaaa tagcagtgtg
    57241 tttggaaaaa gtatactaga aaatatagtt atgggaaatg agggtataag tagagaagat
    57301 gttataaaat catgtgagat agcaaatgca aatcaattta taactaaact cgaaaattct
    57361 tatgatgagg ttttatttca aaggggtaaa aatttatcag gaggacagag acaaagaatt
    57421 actatagcta gagctatagc caaaaaacca caaatattaa ttcttgatga ttgttttagt
    57481 gcaatggata ttaatacaga gacaattata agaaagaata taaaagagta tataagtaat
    57541 ttaagagaaa aggaaagtaa gaaatgtact gtaataacta tttcacaaaa gattagttct
    57601 ataattgact gtgataagat tttagtcttg gatgagggtg aggtggttgg atttgctaca
    57661 catgaagatt tactggttag ttctccaatt tataaaaaaa tttttgcgtt gcagaattta
    57721 gtaagtgaag atgtaaatta aggaggaagt atattgaact taagtactgg aaatcaaaag
    57781 gtcagtagat taaagaaaaa agaaaagcct aaagatttta aaaaaacgtt taaaagaatt
    57841 tttatgtact ttaaaaaaga taagaagatt actagattta tttttttgct agtaataatt
    57901 gattcaatta tatcaactgt aataccatat actattggaa aggtagttga cataatagat
    57961 atcgatactt attcaaaatc cattttctta aaaggaataa ttattttact ttcattttat
    58021 ataattgagt tttcagttaa actgtctaag gggatatgta cagctagatt atctcaaagt
    58081 atagttaaag aaatgagaag taatttattt ttaaaattta aaaatctacc aataaccttt
    58141 tttgataaaa gttctactgg agatattatg agtagagtga caaatgatgt tgataatatc
    58201 agtacaggaa tatcaaattc attagtacag ttaattacag gaatcttaaa catattgatg
    58261 acttttatta tgatgtttgt attaagccca attttaacat tttgcagtgt aatattaata
    58321 ccgatagtaa tgtttgtgag taattttatt gcaaagagaa ctagagtttt ttttaagcaa
    58381 caacaagttg agttgggaaa actaaatgca catattgaag aaatgatatc aaacataaat
    58441 gtagtaaaat cttttaatta tgaaagaaaa tctgtaaatg attttaaaga agtcaatgat
    58501 agacttctaa atatttccct taaatcgcaa atttacactt ctcttttaat gcctattatg
    58561 aatgtgatta gtaatatagg atttgcaact atatgtatta taggaggtgt tcttgcatct
    58621 aaagatatta taaccatagg ggttatagct agttttttaa gttatgtaag acaattcaca
    58681 agacctttaa atgaattagc aaatctattt aatacattac tttcagccat agctggatgt
    58741 gaaagagttt ttgaaattat agatgaacaa gaagagcaag aagtgcataa catgtttaaa
    58801 agtgagatta acgataataa agatggtaat ttaaactctc attttgtaaa gggagaaatt
    58861 gagcttaaag atgtaagttt ttcttatgat tcaaaaaaga aaattttaga taatataaac
    58921 ctaaaaatca aagctggcac atcaaatgcc atcataggag agacaggaag tggaaaaaca
    58981 acgattataa atctaattac aaatttttat catatagatg aaggaagtat atttttagat
    59041 ggtaaggata tatactctat taacagaaac tatttgagaa cttgttttgg agtagttcca
    59101 caagaaggtt atatattcaa tgatacagtt atggaaaata taaggtatgg aaatctggag
    59161 gctactgatg aagaagttat atatgctagt aaaatagcaa atgcacataa atttatagtt
    59221 aaaatgcgtg aaggatatag tactgtatta tcggataggg gtgaagattt aagtgaaggt
    59281 caaaaacaat taataagtat tgctagagca gtattaaaaa atgctccaat acttattttg
    59341 gatgaggcta caagtaacat agatatagca acagaagcta aaattcaaga agcaataaat
    59401 aatttaactt atggaaagac aagtataatt atagctcata gattaagtac catatcaaat
    59461 tgtgataata taatagtttt agaaaatggt agaattgtgg aatcaggaaa tcataaagaa
    59521 ttgataaaat taaagggaca ttattataga aacatattat tgacacaggg aaaataagta
    59581 tttagaaaaa acttttaaaa aaattgttta aaggtatatg gtgcgggtat atatagacta
    59641 acttaataaa taaaaaattt aatttgatat ataaaattta ggaggaaagt aattatgaag
    59701 aaatttgttt gtacagtatg tggatatata catgaaggag atgctgcacc agcacaatgt
    59761 ccagtatgta aagttggagc tgataaattt gaagaaatga aaggcgaaaa aaattgggct
    59821 gatgagcaca gaataggagt agctcaaggt gtagatgaag aaataatcga aggattaaga
    59881 gctaactttg
//
LOCUS       DAEQJM010000017        59021 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.017, whole genome shotgun sequence.
ACCESSION   DAEQJM010000017 DAEQJM010000000
VERSION     DAEQJM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59021
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.017"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            397..1593
                     /locus_tag="KRQ43_001378"
     CDS             397..1593
                     /locus_tag="KRQ43_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBH2741741.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1686..2210
                     /locus_tag="KRQ43_001379"
     CDS             1686..2210
                     /locus_tag="KRQ43_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBH2741742.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDTCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            2235..2411
                     /gene="rpmF"
                     /locus_tag="KRQ43_001380"
     CDS             2235..2411
                     /gene="rpmF"
                     /locus_tag="KRQ43_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBH2741743.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2618..3175
                     /gene="fapR"
                     /locus_tag="KRQ43_001381"
     CDS             2618..3175
                     /gene="fapR"
                     /locus_tag="KRQ43_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HBH2741744.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            3186..4208
                     /gene="plsX"
                     /locus_tag="KRQ43_001382"
     CDS             3186..4208
                     /gene="plsX"
                     /locus_tag="KRQ43_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBH2741745.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            4234..5220
                     /locus_tag="KRQ43_001383"
     CDS             4234..5220
                     /locus_tag="KRQ43_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBH2741746.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5329..6258
                     /gene="fabK"
                     /locus_tag="KRQ43_001384"
     CDS             5329..6258
                     /gene="fabK"
                     /locus_tag="KRQ43_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HBH2741747.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            6274..7224
                     /gene="fabD"
                     /locus_tag="KRQ43_001385"
     CDS             6274..7224
                     /gene="fabD"
                     /locus_tag="KRQ43_001385"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBH2741748.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAILGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIEILLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            7224..7973
                     /gene="fabG"
                     /locus_tag="KRQ43_001386"
     CDS             7224..7973
                     /gene="fabG"
                     /locus_tag="KRQ43_001386"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBH2741749.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTRVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            8027..8251
                     /gene="acpP"
                     /locus_tag="KRQ43_001387"
     CDS             8027..8251
                     /gene="acpP"
                     /locus_tag="KRQ43_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH2741750.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            8280..9518
                     /gene="fabF"
                     /locus_tag="KRQ43_001388"
     CDS             8280..9518
                     /gene="fabF"
                     /locus_tag="KRQ43_001388"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBH2741751.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9744..11462
                     /locus_tag="KRQ43_001389"
     CDS             9744..11462
                     /locus_tag="KRQ43_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH2741752.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLNIGSYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMKSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIIDNIRVAIANKKWNDDVTVTISAGVAHISDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11493..13493
                     /locus_tag="KRQ43_001390"
     CDS             11493..13493
                     /locus_tag="KRQ43_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2741753.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKEKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNVRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTKKEFEEILRILYERRESSSGVGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13841..14086
                     /locus_tag="KRQ43_001391"
     CDS             13841..14086
                     /locus_tag="KRQ43_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH2741754.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            14121..14846
                     /locus_tag="KRQ43_001392"
     CDS             14121..14846
                     /locus_tag="KRQ43_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH2741755.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEEENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14868..16181
                     /locus_tag="KRQ43_001393"
     CDS             14868..16181
                     /locus_tag="KRQ43_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH2741756.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVCGENLKKIV"
     gene            16480..16926
                     /locus_tag="KRQ43_001394"
     CDS             16480..16926
                     /locus_tag="KRQ43_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2741757.1"
                     /translation="MGGETHFLSFGKDEYKISLEEQENAIESAKASDNSVKLIAFIDD
                     EIVGIATIDSNQKAKGKHVGVLGIVVKEKYWGIGLGKRLMLDLIEWCKSNGITKKITL
                     VTNEENYNAIGLYKKVGFEVESILKKECYYNGVYTDLIGMSLLLGI"
     gene            17015..19000
                     /locus_tag="KRQ43_001395"
     CDS             17015..19000
                     /locus_tag="KRQ43_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBH2741758.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTITLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIEEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            19224..20192
                     /gene="spoIIIAA"
                     /locus_tag="KRQ43_001396"
     CDS             19224..20192
                     /gene="spoIIIAA"
                     /locus_tag="KRQ43_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HBH2741759.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIDD
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            20182..20703
                     /locus_tag="KRQ43_001397"
     CDS             20182..20703
                     /locus_tag="KRQ43_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HBH2741760.1"
                     /translation="MQIKIIIIALLVGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20720..20917
                     /gene="spoIIIAC"
                     /locus_tag="KRQ43_001398"
     CDS             20720..20917
                     /gene="spoIIIAC"
                     /locus_tag="KRQ43_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HBH2741761.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20933..21319
                     /gene="spoIIIAD"
                     /locus_tag="KRQ43_001399"
     CDS             20933..21319
                     /gene="spoIIIAD"
                     /locus_tag="KRQ43_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HBH2741762.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21404..22609
                     /gene="spoIIIAE"
                     /locus_tag="KRQ43_001400"
     CDS             21404..22609
                     /gene="spoIIIAE"
                     /locus_tag="KRQ43_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HBH2741763.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22669..23286
                     /locus_tag="KRQ43_001401"
     CDS             22669..23286
                     /locus_tag="KRQ43_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HBH2741764.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            23298..23852
                     /locus_tag="KRQ43_001402"
     CDS             23298..23852
                     /locus_tag="KRQ43_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HBH2741765.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKKQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23879..24568
                     /locus_tag="KRQ43_001403"
     CDS             23879..24568
                     /locus_tag="KRQ43_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HBH2741766.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSDSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24678..25040
                     /locus_tag="KRQ43_001404"
     CDS             24678..25040
                     /locus_tag="KRQ43_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH2741767.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            25125..25631
                     /gene="nusB"
                     /locus_tag="KRQ43_001405"
     CDS             25125..25631
                     /gene="nusB"
                     /locus_tag="KRQ43_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBH2741768.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25615..26685
                     /locus_tag="KRQ43_001406"
     CDS             25615..26685
                     /locus_tag="KRQ43_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HBH2741769.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26682..27887
                     /locus_tag="KRQ43_001407"
     CDS             26682..27887
                     /locus_tag="KRQ43_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBH2741770.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVMVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27889..28104
                     /gene="xseB"
                     /locus_tag="KRQ43_001408"
     CDS             27889..28104
                     /gene="xseB"
                     /locus_tag="KRQ43_001408"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBH2741771.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            28107..28994
                     /locus_tag="KRQ43_001409"
     CDS             28107..28994
                     /locus_tag="KRQ43_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBH2741772.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            29024..29461
                     /locus_tag="KRQ43_001410"
     CDS             29024..29461
                     /locus_tag="KRQ43_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HBH2741773.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29495..31360
                     /locus_tag="KRQ43_001411"
     CDS             29495..31360
                     /locus_tag="KRQ43_001411"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBH2741774.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANNNED
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31493..32305
                     /locus_tag="KRQ43_001412"
     CDS             31493..32305
                     /locus_tag="KRQ43_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBH2741775.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEYTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32325..34004
                     /gene="recN"
                     /locus_tag="KRQ43_001413"
     CDS             32325..34004
                     /gene="recN"
                     /locus_tag="KRQ43_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBH2741776.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLKSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGSFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            34219..35085
                     /locus_tag="KRQ43_001414"
     CDS             34219..35085
                     /locus_tag="KRQ43_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741777.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECTIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGDISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKAYDNIRLEKVDIIVNEGKKD
                     TIYKAQLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(35176..35667)
                     /locus_tag="KRQ43_001415"
     CDS             complement(35176..35667)
                     /locus_tag="KRQ43_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2741778.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIVEAKKIGYTHMRLDTLPSMKSAQGLYEKFGFYDIELYTYNPIEGARYME
                     LKL"
     gene            complement(35728..36168)
                     /locus_tag="KRQ43_001416"
     CDS             complement(35728..36168)
                     /locus_tag="KRQ43_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2741779.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGCGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFKFNGELDYGGEKVMVLKSN"
     gene            36329..37387
                     /locus_tag="KRQ43_001417"
     CDS             36329..37387
                     /locus_tag="KRQ43_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBH2741780.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVGYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37529..38353
                     /gene="spo0A"
                     /locus_tag="KRQ43_001418"
     CDS             37529..38353
                     /gene="spo0A"
                     /locus_tag="KRQ43_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HBH2741781.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38766..39887
                     /locus_tag="KRQ43_001419"
     CDS             38766..39887
                     /locus_tag="KRQ43_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741782.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39905..40780
                     /locus_tag="KRQ43_001420"
     CDS             39905..40780
                     /locus_tag="KRQ43_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HBH2741783.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIVLKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNSLGNTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40804..41496
                     /locus_tag="KRQ43_001421"
     CDS             40804..41496
                     /locus_tag="KRQ43_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH2741784.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41504..42328
                     /locus_tag="KRQ43_001422"
     CDS             41504..42328
                     /locus_tag="KRQ43_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH2741785.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42333..43400
                     /locus_tag="KRQ43_001423"
     CDS             42333..43400
                     /locus_tag="KRQ43_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HBH2741786.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGKIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43402..43938
                     /locus_tag="KRQ43_001424"
     CDS             43402..43938
                     /locus_tag="KRQ43_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH2741787.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            44006..44611
                     /locus_tag="KRQ43_001425"
     CDS             44006..44611
                     /locus_tag="KRQ43_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HBH2741788.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTVSIGIIKFLAK"
     gene            44623..45537
                     /locus_tag="KRQ43_001426"
     CDS             44623..45537
                     /locus_tag="KRQ43_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH2741789.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45579..46751
                     /locus_tag="KRQ43_001427"
     CDS             45579..46751
                     /locus_tag="KRQ43_001427"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBH2741790.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46798..47610
                     /locus_tag="KRQ43_001428"
     CDS             46798..47610
                     /locus_tag="KRQ43_001428"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBH2741791.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47814..49139
                     /locus_tag="KRQ43_001429"
     CDS             47814..49139
                     /locus_tag="KRQ43_001429"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBH2741792.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEVDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSIKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49352..50431
                     /gene="mltG"
                     /locus_tag="KRQ43_001430"
     CDS             49352..50431
                     /gene="mltG"
                     /locus_tag="KRQ43_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBH2741793.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50603..51277
                     /locus_tag="KRQ43_001431"
     CDS             50603..51277
                     /locus_tag="KRQ43_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBH2741794.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFASIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            51264..52511
                     /locus_tag="KRQ43_001432"
     CDS             51264..52511
                     /locus_tag="KRQ43_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH2741795.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRAPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52583..54247
                     /locus_tag="KRQ43_001433"
     CDS             52583..54247
                     /locus_tag="KRQ43_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBH2741796.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54344..54628)
                     /locus_tag="KRQ43_001434"
     CDS             complement(54344..54628)
                     /locus_tag="KRQ43_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2741797.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(54651..56168)
                     /locus_tag="KRQ43_001435"
     CDS             complement(54651..56168)
                     /locus_tag="KRQ43_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH2741798.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKACDLDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAIYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(56293..57114)
                     /locus_tag="KRQ43_001436"
     CDS             complement(56293..57114)
                     /locus_tag="KRQ43_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH2741799.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETK
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKSLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            57305..58732
                     /locus_tag="KRQ43_001437"
     CDS             57305..58732
                     /locus_tag="KRQ43_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HBH2741800.1"
                     /translation="MKIKKLLTIGLSLSIFIASCPISANALDKIESIKGADKYETAGI
                     IADKQNYTTAILINADSTMADGLSASGLAGAINAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSINKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKLVKDTNSTR
                     LGGTDRYDTNKKIINKFYSGVKEFYIASGTDLVYALVGSTIAKNNAIVLVGNDSNKSV
                     LKSTIKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLGVKKFYYE
                     PNYSEDEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDVRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKIYN"
BASE COUNT        23656 a         6126 c        10761 g        18478 t
ORIGIN      
        1 aaatttttaa ttataaaatt aaaaaacgta aaaaaattta taaaaatgta gaaatgttac
       61 ctacataaaa aactggttaa atgttattaa aataacttta ttagctcttt atattatatt
      121 attataacaa atgggaaaga ataatctaca ttaagttaac ttgttaatat attattagtg
      181 aaatacacaa tttaccatac tagaaatatg atataatata aaaaaaaagt atatactttt
      241 atattaaaag gtgatatatt atttatgaaa atcgtttaat gtatacaata atatatctat
      301 aacaaaataa taaaagatag agttttattt agacatttat tacaaatcaa aatttattac
      361 atattattta taaaaaaatc taaggaggaa ataataatga aaatattagt attaaactgt
      421 gggagttctt cattaaaata tcaattaata gatatgaata atgaagaagt tttatgtata
      481 ggattggttg aaagaatagg aatagaaggt tctatattaa aacatgaaaa agcaggtaga
      541 gatgataaat acgttgttga acaaccaatg aaggaccaca aagatgcaat agcattagtt
      601 ttagaagctg ttgctcatcc agaatttggt gcagttaaag aaatgaaaga aatagatgca
      661 gtaggacata gagttgtaca tgctggagaa aaatttgcaa cttcagtagt aataactcca
      721 gaagtagaag aagctttaaa agaatgtata gatttagctc cacttcataa tccagcaaac
      781 ataatgggaa tagatgcttg taaagctata cttccagatg taccaatggt aggtgtattt
      841 gatactgctt tccatcaaac aatgcctaaa tcttcatact tatatggttt acctcatgag
      901 ctatatacta aatatggggt aagaagatat ggattccacg gaacttctca taattatgta
      961 tctcagagag cagcagagat attaggaaaa gatataaaag atttaaaaat agtaacttgt
     1021 cacttaggaa atggtgcttc tatagctgct gttgatggtg gaaaatgtgt agatacatct
     1081 atgggattca ctccattaga aggattaata atgggaacta gatgtggaga tatagaccca
     1141 gctatattac cattcttaat gagaaaagaa ggtttagatg ctgatggatt ggataaatta
     1201 atgaataaag aatctggagt atatggaatg actggaattt ctagtgactt cagagatata
     1261 gaagatgcag ctaaaaatgg agacgaaaga gctcaggcta cattagaagc gtatgttaaa
     1321 aaagtacaaa aatatatagg cgcttatgct gctgaaatga atggattgga tgttgtagta
     1381 tttactgcag gcgttggtga aaatggaaag gctataagag cagatattgc ttctaacatg
     1441 gagtttttag gaatgaaatt agataaagaa gctaatgatg ttagaggaaa agaaacagta
     1501 atatctactg ctgattctaa agtaaaaatg cttttaatac caactaatga agaattaatg
     1561 atagctagag atacattaag attggtaaaa taattaaatt aaacctatgc ctatcaagta
     1621 aaaatacttg acaaacaaat gctagatttg tataataaat ttggtgatat gttgaggtga
     1681 acttaatgaa agttagcata gaaaaaataa atagaaaaga aactgacaaa atagacttga
     1741 atttttgtga aaaaattgat actattagtt attgtgatga gatttacaaa ttagtatcac
     1801 ctgtaaattt aaaagggaaa gtgtcaaaga ctaataaagg tttgtatcta gatatagatg
     1861 tcaattttac aattgttgac acttgttcaa gatgtcttaa agaagtagaa ataccactag
     1921 agtattctat acaaggtttt ttagtaaaag aagaagatta tgatgaagat gagtttgagg
     1981 aatttgatcc ttttatattc gatggtgaag aaatcgacct tattgatata atagaacaga
     2041 cattagattt taatgtacct cataaagttc tttgtagtga aaactgtaaa ggtctttgtc
     2101 aagtatgcgg ggcaaactta aatgaagaag agtgttcttg cagtgaaatt acaaacgatg
     2161 aggaatacat agatcctcgt tttgctaaat taaaagattt atttaattaa attttgacta
     2221 aggaggtggc gtaaatggca gtaccaaagc gtaaaacgtc taaatcaaac acaaaaatga
     2281 gaagagcagc taactcaaag atggaagcaa caggatttgt aagttgccca caatgtcatg
     2341 agccaaaatt accacataga gtgtgtccag actgtggata ttataaaggt aaagaagttg
     2401 tgtctaagta atagcttcta aaaagcatgt agagtatact ctacatgttt tttttgtaca
     2461 tataaaaaaa taagatgatt tactagagaa aataagtgga ttttatgcat attaaaaaat
     2521 agaaaaataa taatataagt attgaaaatt tttgtgtgtt actatatact actattagta
     2581 gctggtacta attacagcta taaaatttgg agggaacatg aaaaagaaaa gtaaagccca
     2641 aagacaaaaa gagcttatag atatgctaaa gacagatcct ttttatactg atgaagaatt
     2701 atcaagtctg tttgatgtaa gtatacagac cataagatta gatagaatga gtctaaacat
     2761 accagagcta agagaaagag tcaaatcaat agcagaaact cagagttcaa aagtaaagac
     2821 tttaggagta aaggaaatta caggagaaat cattgattta tctgtagggc gattaggtat
     2881 atctatgtta gaagttacac aggacatgat ttactctaag actaatactt taaaagatac
     2941 gtatattttt tctctagcag attcattggc aatggctata atagatgcac ctaaggttat
     3001 tatgagagtt gcaaatgtaa aaagttttaa gttgatagaa caacaagata gacttatagc
     3061 aaaagcagaa gtgtatagaa atatagataa aaagcattat gtaaaagttg ttatcaacaa
     3121 taaagcccaa gagcaaatat ttagaggaaa gtttatcttt gaagaattag attaggaggg
     3181 aaattatgaa aatagtaatt gatggaatgg gtggagataa tgcacctaaa tctaatgtag
     3241 aaggcgcagt aaatgctata aaagaatatc aggttgattt aataatcaca ggagataaag
     3301 atttacttga aaaggaattt tcaaattatg aatttgatag aaataaatta gagatagttc
     3361 atactactga gattatagaa aacgaagata aaccagtaaa ggctataaga agtaaaaaag
     3421 attcatctat ggtagtagca ttaaatcttg taaaagaagg aaaggcagat gctataatat
     3481 cagctggaaa tacaggagcc ttacttgctg gtggattatt tgttgttggt agaataaaag
     3541 gaatcgatag accttgctta tgttcagcaa taccaaatgt aaagcgagga atgacactta
     3601 tagcagactg tggcgcaaat gcagattgta aacctaagaa tctagttgaa tttgcagcta
     3661 tgagtaatat ttattcaaga aaagttttag gtcttgaaaa tcctaaggta gcattagcaa
     3721 atgttggact agaagaaggc aaaggcaatg atttagtcaa aaggtcatat gaagaaatta
     3781 aaaaattaga tttaaatttt atagggaatg tagaagctag agaagttata aatgcataca
     3841 cagatataat catatgtgat ggatttacag gtaatatatt acttaaatct gctgaaggtg
     3901 tagcactttc agttatgagt cttataaagg aaacttttat ggccagtaca aaaagtaaaa
     3961 taggagcatt acttataaag gatgatttaa gaaaattaaa aagttttata gattattctg
     4021 agtatggggg agctccactt ttaggtctaa atggaggagt tataaaagct catggtagtt
     4081 ctgatgctaa agctataaaa aatgctataa atcaaggaat aaaattttca aagggaaaag
     4141 tcgttgaaga tattaaccaa tttataagca aatacaatga agaaaataaa aataacgaag
     4201 atgaataaac tcgttttgga ggtttaatat ataatgaata caaaggctgg aatattagga
     4261 gtaggaagtt atctacctga gcaatcatat gataattttc acttcgaaaa aataatggat
     4321 acatcagatg agtggataag tactagaact ggtattaagg aaagaagatt tgccaaagag
     4381 tctgaagcaa cttctgactt agcatctaaa gctgccttaa aagctataga atgtgcaaag
     4441 ttaaacgtag aggatataga gctgattata ttagctacaa ttactcctga tatgtctttg
     4501 ccttcaactg catgtatagt acaagatgca ataggagcag tgaatgctac tgcatttgat
     4561 atatcagcag cttgttctgg atttgtatat ggagtaacta ttgcaaagca atttgtggaa
     4621 acaggttgct ataaaaatgt gcttgtaata ggagcagaaa cttgttctaa gtttttaaat
     4681 tatgatgata gaacaacagc agtattgttt ggagatggag ctggagcagc tgttattggt
     4741 cctgtaaatg agggtggaat actgtctaca catatgggct ctgatggtaa aggaaaagat
     4801 tgtttaaaag tacctgctgg aggttcaaga cttaaggcaa gtaaagagac tgtagaagct
     4861 aatctacata caatagaaat ggcaggtagt gatgtgttta aatttgcagt tagaaagatg
     4921 gcagaaactt ctttaagagc tcttgaaaaa gcaaacctaa atacaactga tatagactac
     4981 ttagtgccac atcaagctaa tataagaatc atacaagctt cttctaagag attagagctt
     5041 gatatgaaaa aagtttatgt aaatatagac aaatatggaa atatgtctgc tgcatctata
     5101 ccagtagcat tagatgaagc ttatagagaa ggtaaaatta aaaagggtga taatgtagtt
     5161 ttagttggct ttggtggagg tctaacttgg ggggcttcag ttgtcaagtg gactttatag
     5221 tataaaatat ctaaaatgat ttaattaaca aaattaaact tatacacaaa ataaagttga
     5281 ttaataataa aaagtttact tttatgattt caagtgaagg agaattgtat gaataaaatt
     5341 tgcaaaatat taaatataaa atacccagtt atccaagggg gaatggcatg ggtagctact
     5401 gcatcattag caagtgctgt atctaatgca ggaggacttg gcataatagc agcaggaaac
     5461 gcaccaaaag aagctataaa gaaagaaatt gttgagtgta aaaaattaac agataaacct
     5521 tttggagtaa atgtaatgct tatgtcgcca tttgttgatg atataattga tttgattata
     5581 gaagaaaaag ttcaagttat tactactggt gctggaaatc ctgcaaaata tatggataga
     5641 ttaaaggaag ctggaacaaa ggttattcct gtagtaccta caatagcttt ggcacaaaga
     5701 atggaaaagt taggagctac agcagtaata gcagaaggta ctgaaggtgg aggacatata
     5761 ggagaactta ctactatggt cttagttcca caagttgctg atgctgtaaa catacctgta
     5821 atagctgctg gaggaattgt agatggtaga ggaattgcag catcatttgc attaggtgcc
     5881 agtgcagttc aagtaggaac tagatttatt tgcagtgaag agtgttctgt gcattcaaac
     5941 tataaaaact tagtactaaa agcaaaagat agagatgcaa ttgtaacagg aagaagtact
     6001 ggtcatccag taagaacatt aaaaaataaa ctatcaaaag aatttttaaa gatggaacaa
     6061 aatggagcta ctcctgaaga attggataaa aaaggtacag gagctttaag atttgcaaca
     6121 gtagatggag acatagaaaa aggttcattt atggcaggtc aaagtgctgc tatggtaaaa
     6181 gaaataacac cttgtaagga aattatagag gctatggtaa atcaagcaag agagattatg
     6241 ccagcaatag aactgtaaat caggaggagc aagatgggaa aagttgcact agtattccct
     6301 ggtcaaggag ctcaatatgt aggtatggcc aaggatttat atgaaaataa tgctgttgct
     6361 aaaagtgtaa tagatgaggc tagtgatgcc ttaaatatgg atttaaaaaa ccttatgttt
     6421 aatggaaatg aagaagaact ttctaaaact gaaaacactc aacctgctat ggttacacat
     6481 agtgtagcag tattaaaagc ggtacaagct caaatagatt taaaatataa tgcatgctta
     6541 ggattatcct taggagagta tagtgcgttg gttgcagcag atgcaattga ctttaaagat
     6601 gctgtatgtt tagttaaaaa aagaggtaag tttatgcagg aaacagttcc agcaggtgtt
     6661 ggagctatgg cagcaatttt aggtttagat agaaatgtac ttgaaaatgt ggttaaagat
     6721 atacaaggag gtattgtaga agtagcaaat tacaattctc ctggacaaat agttatatct
     6781 ggtgaaaatg aaaagataga agaagcaatg gtaaaatgca aagaagcagg agcaaaaagg
     6841 gcagttaaat taaatgtaag tggacctttt cactcatcaa tgttaaaaga agctggtgta
     6901 aaattggcca gtgaattaga aaaagttaac ataactaaac ctaaagttga tgtggtggca
     6961 aatgtaaatg cagattacta taaaaacgaa ggtaaagacc tgcttataaa acaagtaagt
     7021 tcatctgttc tttgggaaga ttctatagaa atacttttaa atgatggata tgatactttt
     7081 atagaaatgg gacctggaaa aactttaaaa gcatttatta agaagatagc ttccaataaa
     7141 aaagcaaatg tcaatattta taatatagat ggtatagatt ctcttaatga atttgtacaa
     7201 aattatagaa atggagagat ataatgataa atcttacagg acaagtagca gttgttactg
     7261 gtggctctag gggtatagga aaagaaatag caaaaaaact agcatctttt ggagctgatg
     7321 tagtaatcaa ttatacttct aaagaagatg aagcactaaa aactaaaaat gaaatagaaa
     7381 gtatgggggt aaagtgtacc tctataaaat gtgatgtgtc taaatttgat gaagtgaatc
     7441 aaatgataga ttctgttgta agcgaatttg gaaaaattga tatattggtt aataatgcag
     7501 gcataactaa agatggtctg cttatgagaa tgaaagaaga agattttgat agagttatag
     7561 atataaactt aaaaggtgtc tttaattgta caaaagcagt tactaaacct atgatgaaaa
     7621 agaagtatgg aagaataata aatatgactt cagtagttgg aattatgggt aatgcagggc
     7681 aaactaatta ttgtgcatca aaagcaggtg taattggatt tacaaaagct tctgcaagag
     7741 agttagcatc aagaaacata aatataaatg cagtagcacc tggatttata gaaacagata
     7801 tgactagagt actaagtgat gatgtaaaag aatcaacact agcaaacata ccaaagaaat
     7861 cttatggtaa accagaagat gtagccaatg ccgtagcatt tttagttagt gacatgtcaa
     7921 gttatataac aggacaagta ataaatgtag atggtggaat ggtaatgcaa taataattta
     7981 aaaagtagag aaatctatta aaataaaaaa ttttaggagg tacacaatgt ttaataaagt
     8041 tgtagaaata ataatagagc aattaggagt agaagataaa gaaataacta tggagacatc
     8101 attaatgaag gatttagaag cagattcatt agatgcagta gaaataataa tggcacttga
     8161 agatgaattt ggtatagaaa taccagatac agaagcagaa aacttcaaat ctataggaga
     8221 tatagttaag tatatagaag ctaataaata gtcgagcttt aaaaaagtgg aggtatccga
     8281 tgaataaaag agtagtaata acaggacttg gatgtgttac gccgttggga acgggaaaag
     8341 aagagttctg gagtaatata aaatctggag tatctggtat agataaaata actaattttg
     8401 atgctagcac atatcaaact cagatagcag gagaagttaa gaattttcat ccagaagaat
     8461 atataagtaa aaaagaattg aagagattag ataaatttgc tcaatttgca atagtatctg
     8521 ctaaattagc agttgaagat gcaaatcttg atttagataa agttgataga gaacgttttg
     8581 gtgttataat aggttctgga ataggtggag ttgaagctat agaaactcaa cataaaattc
     8641 ttttggaaaa aggaaataaa agagtaagtt cactttttgt acctatgatg ataggaaata
     8701 tggcagctgg tcaagtttca atatttttag gagcaaaagg gcctaacact aatgtatgta
     8761 cagcttgtgc atcaggaact cattcaatag gtgatgcttt taaggtaatt caaagaggtg
     8821 atgcagacat catggtagca gggggctctg aagctgctgt aacaggtctt gcttttgctg
     8881 gattctgtaa catgaaggct atgtcaacta gaaatgatga ccctaaaact gcatcaagac
     8941 cgtttgataa agacagagat ggttttgtaa tgggagaagg agcaggtatt gttatcttag
     9001 aagacttaga acatgcttta gcaagagggg ctaaaatata tgcagaagta gttggatatg
     9061 gtttaactgc tgatgcatac catatgacaa ctccagctga aaatggagag ggagcagcta
     9121 ggtctatgaa tatggctttg aaagatggaa atgttccatt agaagaagta gattatataa
     9181 atgctcatgg aacttcaact tattacaatg atttatatga aactatggct ataaaaactg
     9241 tatttggaga aaaggcatat gacttatgtg tgtcatcaac aaaatctatg actggtcact
     9301 tattaggagc atcaggtgct atagaggctg ttgtttgtgc tatgagtata gaagatagtt
     9361 ttgtgcctcc aactataaac atacaagaag ttggtgaaga tttggattta gattatgttc
     9421 caaatcaagg taaagaaaaa aatattagat atgcactatc aaattcttta ggatttggtg
     9481 ggcataatgc tacaatagta ctaaaaaaat atgtataaat aaatattaaa tataaaacta
     9541 aaaaacaagc acttgtttta actgtataaa tttatattag cttaaattta aagtctccta
     9601 aattatttta ggagactttt ttattaagat ttaagtctag catatgttgt aaatcatttt
     9661 gatatattgt attattaatt attaagaggt tatttatata tgcaagtttt cattctacaa
     9721 tatacaaaag gaggactaaa attttgaatt ttagactacc aaagaaaagg ttacccaaaa
     9781 agataatttt tatatgtata atacttatta gtattatttt gtttataaag tatgaccaaa
     9841 atggattgaa agaaagagaa attataaata agggaaaata tatgtctgaa agccttgtgg
     9901 cagataagga gtatgatgaa gcaaaaaaag tggttaagac ttctttcgaa tctattccag
     9961 aaaaaaaata caataaagta tataatgaag tttgggatat gttaaagact atttcatatg
    10021 ttccagatgg aacgaagata gtcattgatt ctttagaaaa gatgagagaa tcagatgtga
    10081 aattatctga tgaatgtaga tttaatatag aaaaaagatt agcatcagtg tatataatgg
    10141 ataataatta ttctaaggca gtagatttaa ctgtaaagtc tataaaattg gctgagaaat
    10201 tggggaataa ttatgaaaaa gcaagactag atgttgattt ggcgagcata tttttaaata
    10261 taggtagcta tgaaacagga gagaaattaa taaaggattc ttttaaaata gatattgatg
    10321 aaggtgaaaa aaatggaatg gttagattat atgctattat aaatctagca gaaatatatg
    10381 tagaagaggg agaatatgat aaagctattg aaataagtag caggataaaa gattataaaa
    10441 agtttgtaaa tacggataat tacaatgatt ttgatataat ggcctctata atgaagtcaa
    10501 atgcgtatgt gggcaaaaat aatatacaaa aggcaaagac ttttttagaa aaagctgatt
    10561 atcttataaa atcagataga acagtttata tattagataa agatatgtac tattatatgg
    10621 caatgggaaa cttagaatat aaaagcgaaa attataattc tgcaatagat aattataaaa
    10681 aaagtttaga gatatctacc aaaagaaagt taactcagga gaaaataaaa aatttaaata
    10741 agatattaaa tatatatgaa aaacaaggaa atatagaatc tttaaatgag tatcaaaaga
    10801 tgttaataaa tgaatataaa gagaacaaaa gtataagaga ttcagagact agtttctata
    10861 taattgataa agtatcaaac gaaagtaagc tatttgaaaa aactaaaaaa gaaataaaat
    10921 attataaaat attatttaca gtaattttaa ttgctatatt agggtctact tttttataca
    10981 accgattgaa gtattttaaa gcacaaaatt tacatgatgg tcttacaaat gtttataata
    11041 gaaaaagttt tgatattatg tatgaaaagt acagagagaa agatgataat tttgcacttg
    11101 tgatgataga tattgataat ttcaagctca taaatgataa ttatggacat aaatttggtg
    11161 acactgttat aaagggaata acaaatacca tttgtgttat gttagaacaa gatgataaag
    11221 tctttaggta cggaggagaa gaattttctg tattaataag aaataaatct ggtgaggaag
    11281 tagcagatat aattgacaat ataagggttg caattgcaaa taaaaagtgg aatgatgatg
    11341 tgactgtgac tataagtgca ggtgtagctc atatttcaga tagcaaagat gtactagaag
    11401 aagctgataa aaatttatat aaagcaaaac aacttggtag aaataaagta gtatataagt
    11461 aattatatac tatataaata agaggtataa atatgaaaca atcaatagct atagtaactg
    11521 ataaaataac taaactatca tctttcttag aagaaaatat acgtttggtt ttaggtaatt
    11581 atattgatat aaaccactat tatctggaag ttttaaaaga gaatgataaa atacaaggtg
    11641 attttgtact agtaatgaat gatgatagat taaacagtat gagaaagcat ttagtacaag
    11701 atagtaagat tatagtgata aggagaacac ttaaagaaaa tgaaatatat ggattatttt
    11761 caataccaaa tggaactgaa gtattggttg taaatgatac aaaagaaact accttagaaa
    11821 cgataagctt attttacaaa ataggagtaa aaaatttaaa gtttactcca tatattgaag
    11881 gaaaaattta taaaaatata gacatagcta taacgcctgg agtaaaggaa aaagtaccaa
    11941 gttatataaa taaagtaatc gaccttggta atagatatat tgatatatct acttttatag
    12001 aaataataaa tggtcttaga attgatgtta aagaaatacg taaaaattta atggcatatt
    12061 ctgagagttt aataagttta gataatggag ttaaagataa ttataggcaa ctgtttttaa
    12121 aaatagaaga acaagatgtt atattgaatc tatcaaaaga tggaataata tttacttcag
    12181 cagatggtat aataaacaca tttaataaag aagctttaaa aattttaggt ataaatgaaa
    12241 atccacaagg caaaaacata gaagatatca tttctgaaga tttaaatatt ttacttgaag
    12301 acaaagaaat aattgatgaa gtggtattta caaataaaaa atatataaat gtaaataaaa
    12361 aaagtatttt ttctatgggg aataaagctg ggatatatta taacttacaa gaaataacgt
    12421 atataaaaaa attagaacaa aatcttacta ataaattaag agaacaaggt cagatagcaa
    12481 gatatacatt taaagatata aaaactaaaa ataaaaatat ggtaaagtgt gtagaattgg
    12541 ctaaaaaaat atctaaatca gacctttctg tattaataat aggagaaagt ggtactggta
    12601 aagaattatt atcacaatca attcataatg cttccaatag aagtaatcaa ccatttatag
    12661 cggttaattg tgcagcagtt ccagatagtc tattagaaag tcaactgttt ggatatgaaa
    12721 aaggctcttt tacaggagct ttaagagaag gaaaaaaggg tctatttgaa cttgctaata
    12781 atggaactat atttctggat gaaattggag atatgcctcc attgctacag acaaagttac
    12841 taagggtatt acaagaaaag caggttatgc ctataggttc ccataatgtt ataaacatag
    12901 atgttagggt catagcagca acaaacaaaa acttactaaa gatgattaga gaaggaaaat
    12961 ttagagagga cctgtattat agactaaatg tattgccaat agatgtacca tcattgagga
    13021 atagaaaaga agatataata acacttatga atttcttttt gaaaaacaat gtaagacttt
    13081 cgccagaagt tataactatt ttagaaaaat ataattggcc aggaaatata agagagttac
    13141 aaaatgttgc ttcttatgta agtctaatgt gtgatagtat ggtttttaga gatgacttac
    13201 caccatatat aagggtagaa tgtgctaaca attatgaaga tggatttggt tatacaaaaa
    13261 aagaatttga ggaaatactg aggattctat atgaaagaag agagtcatcc tctggagttg
    13321 gaagagggtt tataatcgaa aagcttatac aggaagggat tgagatttct gaaagcaaag
    13381 ttagaaaggt gctatcttat ttaagtgaat gtggatatat atcatctaaa tctggtagag
    13441 gaggaagtca aataacctca gaggggataa aactttataa taatataaat taagctaagt
    13501 atttgatatt gaaatcacat attttgaatt tagatattta aataataaac ttttatattt
    13561 atagagatta atttatacta tgtcagaaag aatattgtaa tttataatta aatattaata
    13621 ggtttttaaa ataggattag ataggtaata ggttaagtta gaataaccca ttacctattt
    13681 ttatttgtaa gaaaagtgta catagagtta aaagtaaaaa atacaactaa taaaactatt
    13741 gaaaacacta gataaataat aaataaaaat aattataaat tttggcatat atattgctaa
    13801 tcatagagat aagacgacaa aataattggg aggtttaatg atgaaataca aaacaacagg
    13861 gacttgtgct acagaaattg aatttgaagt aaaagaaaat aaagttacaa atgtaaactt
    13921 tataggtgga tgtgatggaa atttaaaagg gctaaaagta ttagttgaag gcatgaatat
    13981 agaagatgta atacaaaagt taaaaggaat agagtgtaaa acaaagccaa catcttgccc
    14041 agaccaactg tctctagcat tggaaaatta tatgaatata aagtaataca taaaacaatc
    14101 gattagttag gagtttaatt atgaaaccaa taatagggat tttaggaaat ttaataataa
    14161 tggaaaatgg tatgtttcca ggtcttgaaa ggtcatatgt aaataatgat tatataaatg
    14221 cagtgctaaa aggtggcggt agtccagtaa taattcctgt aaatacagat aaagaagtta
    14281 taaaaaaaca gattgaaatg gttgatggag tcttaatatc tgggggatgg gatatcaatc
    14341 ctcaactgta tggagaagaa acaagagaag aaacgacatt tatatatcca gaagtggatg
    14401 aatttgattt aattgcaata agtatagcat tagaacttaa aaagcctata ttaggtgtat
    14461 gtaggggact acaaatttta aatgtaagtt taggaggaac tttatatcaa gataataatc
    14521 ttatagaagg aagttatata aaacatacac aatcttctaa aagacatgta gctactcata
    14581 aagtcgatgt taaagaagga agtattttag agggaatttt aggaaaacaa ttacttacaa
    14641 atagttatca tcatcaaagt gtcaatcagc ttggaaaagg attaaaagcc atagcatact
    14701 caaaagatgg tataatagaa gctattgaga aagaggagga aaattttgta gtaggagtac
    14761 agtggcatcc agaaatgatg gtagattact gtgataaaat ggaaaaacta tttaaatatt
    14821 ttataaatat ttgttcaaat ttataatata ccttgggggg attgaacatg aacgaaaaga
    14881 acaaaatggg attaataagt attatacttt taggtattaa tgcagtagta ggagctggag
    14941 tttttctatt accaggagat gcaatgaaat catttggtgt agcaagtata tttgtatata
    15001 tatttgatat gttgttagtt ttatctatgg cattctgttt tgctgaggtt gcaggtaaat
    15061 tcaataaaaa tggcgctgcc tatgtatata ccaaagaagc ttttggagat ttttgtggtt
    15121 ttgaagtagg tcttatgaaa tgggtaatag gatgtatttc ttggggagct ttaatagtag
    15181 gttttcctac atcattatca gcagtatggg ctccagcagg tgaaccacat atacaaaaaa
    15241 ttataattgt agccatgata gttgggctta caattataaa cttattaggt gtatctctat
    15301 caaaaattgt acaaaatgtt ataactgtag gtaaactaat tccattaata ctatttatag
    15361 gaataggtat attttttata aaaggagtta attttacttc ttcaacaatg gtacctccag
    15421 gagctggagc aacagagttt ggagcagcag cacttttaat gttttattca tttacaggat
    15481 ttgaatctat agcagttgca gcagaagata tggaaaatcc acaaaaaaat ataccaatag
    15541 caattataag tgtaatagta attgcatcaa taatatatat attaaatcaa gttgtatgtg
    15601 ttggtatact aggagattcg ttatctagta catctacacc agtggcagat gctgcaagaa
    15661 tatgctttgg aaatatggga gctggattgg ttacctttgg aacattggtt tctgttggtg
    15721 gaatttgtat gtgtggtgct tttgtaaatc caagaagttg tgtagcttta gctgatgata
    15781 aaatgttacc aagaatattt gcaagaaaag ataaaaaagg tacaccatat gtagcgataa
    15841 tagctactat gttaatcact ataccaatag ctctatctgg aagttttgct gaattagcag
    15901 caataagtgc agttgctaga ttcatacaat acataccaac atctttatcc gtattagtgt
    15961 ttagaaagaa aagaccagaa ttagtaggta cttttaaaac tccttttgga gcagtgattc
    16021 ctctaattgc tgtatgtgtt ggaacatggt tgttattcca agcatctatg catcaattaa
    16081 ttatgggatt aggagctttg gcaattggag taccattata ctttataatg aagtcttata
    16141 atagaaaagt ctgtggtgaa aatttaaaga aaatagttta attatgttat aagaatttat
    16201 tgagttaaaa ttagacattg gcagaaaatt aaatacaaat aagtatctat aaggctatat
    16261 taaaatatta ttaatttttt attttaatat agccttatat tgttatcaat aaatgaaaaa
    16321 tattgtaaca acagaagaac aatagtatta tgtttataga taaaaaactt attaggaggt
    16381 aaatttatgc caacaataac attaaaaaat ggtgtagacg tacttattag agaaggtgta
    16441 agagaagatg cttaaagcat tatagatttt tataatgaag tgggtggaga aactcatttt
    16501 ctgtcatttg gaaaggatga atataaaata tctttggagg aacaagaaaa tgctatagaa
    16561 tcagcaaaag catctgataa ttctgttaaa ctgattgcat ttatagatga tgaaatagtt
    16621 gggattgcaa cgattgattc taatcaaaaa gcaaaaggaa agcatgttgg agtattagga
    16681 attgttgtaa aagaaaaata ttggggaatt ggattgggta aaaggcttat gttagacctt
    16741 atagaatggt gtaaatcaaa tggaataacc aagaagataa ctcttgtcac taatgaagaa
    16801 aattataatg ctataggatt atacaaaaaa gttggatttg aagtagaaag catactaaaa
    16861 aaagaatgtt attataatgg tgtttatact gatttaatag gaatgtcact tttattggga
    16921 atataattag tgtacatttt atctcgaaaa aagtatatta agtatggtat aattaaaaaa
    16981 gaatataact taatataatt ttggaggacg aattatgaaa aatctgtgta aaatatcaga
    17041 tgattattta aacagcaagc ttaagtattt aaagttatta tcaaaacaat atccaagtat
    17101 atcaaaagca agtacagaaa taataaattt agaggctata ttaaatcttc caaagggaac
    17161 agagcatttt ataacagatg tacatggtga atatgaacca tttgtacatg tattaaaaaa
    17221 tggttctggt gtaataaaga gaaaaataga agaattgttt tcaaatacaa taagagacag
    17281 cgaaaaaaaa atgttagcaa ctcttgtata ttatcctgaa caaaagttag acctaataat
    17341 taagcaagag gaaaatatag atgattttta tagaataaat atttatagac ttatagaact
    17401 ttgtaaatat gcttctagca aatatactag gtctaaagtt agaaaactgt taccagaaaa
    17461 ttttaaatac ataatagaag aacttttgca tgagcatgtt aaaagtgaac ataaagaaga
    17521 gtattataaa agtatagttg aaacaatagt tgacatagga atagctaagg agtttataat
    17581 tgctatttct acagttatac aaaaattggt tgtagataga cttcatgtaa taggagatat
    17641 ttatgataga ggtccaagac cagatataat tgtcgataag cttattgaac atcattgtgt
    17701 ggatattcaa tggggaaatc atgatatatt gtggatgggt gcagcctcag gtgaaaaaac
    17761 ttgtatagca aatgcactga ggatatcagc tagatatgcg aatttagaca ttgtagaaga
    17821 catatatgga ataaatctgt tgcctttagc cacttttgct atagaaatgt ataaagatga
    17881 cccttgtaaa gaatttattc caaaggttaa tgaccaaagt gtaacaacaa cagaaaagtc
    17941 tttaatggca aaaatgcaca aagcaataag tataattcaa tttaagcttg aaggtgaggt
    18001 tataagacga agacctgaat ttgaaatgga acatagactt ttgcttaata tgataaacta
    18061 tgatgaaggt acgattactt taaaaggtaa aacatataaa ttaaaagata cttatttacc
    18121 tacaatagac aaaaaagacc catataaatt aactatggaa gaaagaaatg ttattgataa
    18181 attagtatct tcatttagag gtagtgaaaa attacaaaaa catgtttcat ttttgttttc
    18241 taaaggaagt atatatttaa aggctaactc aaatttactg attcatggat gtgtaccatt
    18301 aaatgaagat ggaagcttta tgtctatgaa tataatggga aaagagtata aaggtaaggc
    18361 tcttatggat aagatggagt ctctagcaag agaaggattt ttctttaaag ataaggcaga
    18421 agaaaaacta tatggtatgg atattatgtg gtatttatgg actgggaaat gttcatcatt
    18481 atttggtaaa gatgatatga ctacatttga aagatacttt atagaagaaa aagagactca
    18541 taaagaaaat aagaatccat attttaaact tagagaaaat gagatggctt gtaaaagatt
    18601 atttgaagaa tttgatttag agcttgatga atcccatata ataaatggtc atgttcctgt
    18661 ggagagtaaa aatggagaga gcccaataaa agctaatggt aaaattctcg ttatagatgg
    18721 tggtttttct agggcttacc aaaaaactac tggtatagct ggatacactt tgatatacaa
    18781 ttctagaact ttgcaattag tatcgcatga accatttaat tctgctgaag aagccattgc
    18841 aaatgaaagt gatatcttat cgacaactgt tgtagtagag cataaggcaa agagaaaaat
    18901 ggtgagagat actgatgaag gagtaaaaat acaagaggaa atagaagatt taaaactact
    18961 tttaatggct tataagaaag ggctaataaa agaaatgtag atattataga ggcacttcat
    19021 aattgaagtg tcttcttgtt aatacttatt aaatatatta taaagattaa taatagtagt
    19081 ttatattata cttactaagt gaatccaaga taaatgggtt cacttttttt atttataaac
    19141 attattaaaa aaatatagat gttttggtta tattccttgt cctttataaa tagaattata
    19201 taaacaaagg aggaggacaa gagatgaata aactttctga tgaaataata aactctcttt
    19261 ctacaactat aagagaaaag gtagaaaaag tctcaaacaa taatctgaac atagaagaaa
    19321 ttaggttacg ctcacaaaaa ccattgatac taaatgcaaa ctctaaagat tatttttaca
    19381 atcaaaaaac tatgacactt gatttaaatc aacaaaactc atatgtagta acaagagaag
    19441 atgtagagca aacttttcaa ataatatgta aatattcaat acattcattt atggatgaca
    19501 taaaaaaagg attcataact ttgagaggag gtcatagagt agggttagtt ggaaaagcaa
    19561 tagtagaaga tggacaagtc aaaaatataa agcatatatc atctttaaat ataagggtat
    19621 caagggaaat tattggatgc tcggataaga ttttaagtca tattataaag ggaaaaaatc
    19681 agattaataa tactttgata atatcaccac ctcaatgtgg aaaaacaact ttaataagag
    19741 atatagtaag aaatttaagt aatggtaatg aagattatgg atttaaaggt ttaaaagtag
    19801 ctttggtaga tgagcgtaat gagatagcag gagcttatct aggtgttcca caaatggatg
    19861 tgggaataag aactgatata atagaaactt gcccaaaaga tttgggtatt acgatgcttt
    19921 taaggtctat gtcaccaaat gttattgtga cagatgaaat tgggagtgaa aaagaaataa
    19981 aggcattata cacagcatta aatggaggta taggattaat aactactgtg catggagatt
    20041 caatagatga tatacaaaat agaaaagaat taaatagact tctggataaa gagttattta
    20101 aaaaggttat aattctttct gcaaaaagag gagcaggaac gattgaaaaa atttatgatt
    20161 tagaagaaaa gagatggtat tttgcaaatt aaaataatta ttatagctct cttggtagga
    20221 agtagttatt tgataggtga acaaatatac aaaacttata ctcgtagaca taaacaatta
    20281 aacgatttaa taagagtttt agaaattttg aggatggatt tatctttcgg actttataca
    20341 ttagaagaaa tctttaatag gataggtgga aataaagagt tttgtttttg gaaatttttc
    20401 tatcaaatat cagaaggact tcacaatgaa caaagtaaaa ctttggaaat aataatatca
    20461 gaaaatattg atgtcttaag taaagaaact tatctaggca ataaagaaat tgaggaactg
    20521 aaaaatctaa tacttacttt agggaaaagc gatatagagt cacaacaaag aatgatagat
    20581 ttatctatag aaaatttgaa aaaacaaacc tatgagacaa aggaagatat aaacaaaaaa
    20641 ggcgtattgt ataaaaaatt agtgacattc ataggtatag gtatatgtat tatattgatt
    20701 taatatgggg aggtttatta tggaaatatc attgatatta aaggttgcag gtgtcggtat
    20761 tctaatatca gtattgaata tgatattgga aaaaacagat agaaaagatt gggcaggtct
    20821 tactacatta gcaggtgtaa taatcgtatt gggtatggta ataacagaaa taagtgactt
    20881 gtttaatact gtaagaacaa tgtttcaact ttactaaaaa ggagggagta atttggaaat
    20941 aatgcaatta ataggaattg caatcatttc aactacactc tgtttagtaa ttaaaaaaga
    21001 tagaccagag atagcaaatt tcatagcaat aataactgga gtaataatac tattgtcagt
    21061 tatgtttaag ctaaatttta tagtagatag tatacaagat ttggctaaca aggctaacat
    21121 accgactatg tatatatcat taataataaa attaattggg atagcatact taatggaatt
    21181 tgcgatacaa ctttgtaaag attgtgggga aggaaacatt gcttcaaaac tagaatttgg
    21241 aggtaaaata atagttatgt caatgtcttt ccctatactt ttgtccattg tagaaatggt
    21301 ggtgaatata attccataga tgtgtatctt ggaatgaata taagtatatt agagaacttt
    21361 cgttgtattg aggtttatag agtgaagaga ggcatggttg cttatgaaaa aaagattttt
    21421 accaatgatt ataggttttt tatttacttt cttttttgta aatatctttg ctattatgat
    21481 atttgctaat gaagtaccaa gtagtgaaga taaagaatat ggtgaaacaa aaaatagcat
    21541 agataaatat atagatggtc aattagacaa gctagatata aatgagattc aagactatat
    21601 aaataaagaa atagttatta atgatgttaa tttaaaatca tttgtaaaag atttaattag
    21661 tggagaaaaa aatatcttag atttattcaa taaagatgga ttgaagatat tgatgtttga
    21721 tgaatttaaa gcaagtttaa aggtagtagc agtaattttg gtactggctc tgttatcatc
    21781 tattttaaag agtctggaaa actctttttc atcaggtgca gtaagtcaaa tagcaacata
    21841 tataatattt atcacaatgg tatcacttac acttattggt tttaaagatg tattacagat
    21901 ttgttatgat gcaatagacc atactgtagg tcttatgcaa gttataatgc caatattaat
    21961 aacattttta cttttaattg ggttcccaat aacgtcgact actttgaatc ctatcttcat
    22021 aggaggagta acatttataa atgtattttt taaaaatttt ctatttgtat ctattactgt
    22081 tgcatttgga attttaataa taaacaattt atcaaaaaat ataaggctaa agagattttt
    22141 ctcctttgta aaacaaataa attatgtttc tattggagct atgtttactg tttacttagg
    22201 tcttgtatcc atacaaggat tgtatgtaac cagttttgat aaattcagtg taaagactgc
    22261 taaatttgct ataggtaatt ttattcctgt tgtaggtgga tttgtatctg actctgtgga
    22321 tattttatta tcttcatctc agcttataaa aaatatattt ggaggaatag ggcttatctt
    22381 acttgttgga atttgtttac ttccagtaat aaaaatttta tcagtaatag tagtgtacaa
    22441 attagcagca ataattgtag agcctgttgg agaggatgga atatctaatt ttttaaatga
    22501 agtggcaaat ttaatgataa taatgctagc atcagtaatt gctataacag taatgttctt
    22561 tgtaactgta gctatcttga cctcgataag tgtcgtaagt caagggtaat ttatatatca
    22621 gtgaaaaata attacattta atctaatgtt tttagagagg aggatgctat gttagagggc
    22681 ataaaggcat ggatagttag tgttttgata ggagcattta tagtaaatat agtagatatg
    22741 attttaccaa gttctaagat aaaaccttat gtcaacctag ttttaaactt tatgtttgta
    22801 tttattgtaa taactccagt agtaggattt ttttcaaaag atatgagttt agaagataga
    22861 atattaaaat ctatgggaaa ctacaacaag cagtatgtag atagtacaaa tgctttggca
    22921 aaagagactg gaaataatag tctatccaag ggatatgagg atgggttaaa agaagtactt
    22981 aaattaaaac ttgatgaata tggttatgat ttagaagata tagagcttaa tggggcaaat
    23041 ataaataata taaaaataaa agaaaagaat aatagtgcaa aaagtaataa cagttccaat
    23101 gaagaaaata aaaataatag tactaaaaga gaggaagaaa acataaactc taatgacaaa
    23161 gaaaattcta aacaagtctt caaaaaaggt acagagtatg ggttgaacct aaatgaagaa
    23221 aaattaaaaa acgacttaat aaaggtgctg gatgtttcta tagaagatat acaaattgat
    23281 aaataggagt tgggagaatg ttgaaaaact taaatgacaa agataagaga aaggtatatt
    23341 cactaataac tatagcagga atatgtgtgg tttcattagt attattatct tgttttccta
    23401 gtagcaaaag tgataaacaa gttggaaaaa cagagactaa taaaaatgct gaaaagcaag
    23461 tcactaaaaa acaagaaaaa gatgatttag agtcaaaatt aacagcaata ctatctaaaa
    23521 ttgatggtgc aggagacgtt gatgtaatgg ttacatttga atcaagtgaa gaaatacaac
    23581 ctgcttttaa ttcaaataat acaacagaaa caacagagga aaaagatgca caaggtggag
    23641 aaagaacagt tacgacttct agtgaaaata aaacaatgat aacttcaaat tcaagtgacc
    23701 ctgtagttat aaaaactaca gagccaaaga taaagggagt gatagtggta gcaagtggag
    23761 caagtgaccc aagtgttaaa gagacacttt atagtgcagt acaaacatca ttacaagtag
    23821 ctggtcatca agtagaaata tattctaaat aaatacatat aaccgggggg ataaatgaat
    23881 gaagtttaat tataagggaa gaggatttgt aataataact ttaactgcaa tgttagtggt
    23941 agtaggaaca gtgaattatc aactaagtaa gaaatcttta ttagaaacat caaaagagtt
    24001 taaggcatat gaagaagcac agttgcaaaa aaatactgat gatagtgata gtagtaagac
    24061 agaggattct agtaatgtag ataaacaagg tggtaaggaa agtgctgata ttgatatagt
    24121 cgatagcaaa gctagtaaag taaaagaaaa ggcaactgag acaagtaagg aaataaaagc
    24181 tcaattatca tcagagaaaa atatgaaaaa ggcatcttat attttagata tgaaaatgaa
    24241 tagagaaaaa caaagaaatg agttagttca agatttaaat gaaatgataa ataatccatc
    24301 tacaacagaa gaatctagaa aagaagcttc taatatgaaa ttaaatatag ttaaaattca
    24361 agaaaaagaa cttcaaatag aaaacctttt gagtacaaaa ggatatgaag aagcgttagt
    24421 ttatataagc gataacaaag ttaatgtagt tgtaaatgaa gctaaattag aaaagaaaga
    24481 tgcagcaaaa atatttgatt tagttgcaga acaagccaat gtgaagtatg aaaatattaa
    24541 acttacaaat aataatagta ataagtaaag tataaacctc agaattaact gaggttattt
    24601 tcttgcaaag tagacttgta tttggtatta ttatacttat aaaaatagtt ccttaaaatc
    24661 aggaggtaag ttttaatatg gaagataata aatttggaca agtaaaaata tctaatgatg
    24721 taatagctac aatagctggt ttagcagcat tagaagttga aggcatagaa actacagcaa
    24781 cattaacaga taagttgtta aaaaataatg gagtaaaaat acaaatcgaa gaagaggatg
    24841 ttaatttaga tgtaatggtt acgataaagt atggaatgtc aataccagat acagctttta
    24901 aagttcaaga aaatgtaaaa aatactgttg agacaatgac aggactgaag gtttctcaag
    24961 taaatataca cattcaagga atcagcttta agaaggataa agttgataaa gaagaagcaa
    25021 aagcaactaa gaaaaattaa tattagccct ctgaaaagtc agagggtttt ttgctggtaa
    25081 ttgattttat atggataatt aaacttaaag gagaattttg attgatgaaa aaagataggg
    25141 cacaaaagag tacaacaaga gaatatataa tgaaacttat ataccaaata aatattaata
    25201 aagaagattt tgaaacttta gaagataaag tagataattt tttaaaagat aattcagaac
    25261 atattataaa tagatataaa gaacttgcac ttcaatactc aaaaaataca aatttaaagt
    25321 tagaagatac tgaaattgaa gatgttatag acaagaaata tataaataca gtatgcaaag
    25381 cattaaaaga aaatcatgac aaaatagatg agttaataaa taagcatgct aaaaactgga
    25441 cagtagatag aatgccaaag gtagatgttt ctatacttag attgtctgtg tgtgaaatac
    25501 tttatttaga cactcctaat aaagtatcaa taaatgaagc ggtagaactt gcaaaaatat
    25561 attgtgatga taagtctcct aaatttataa atggtatatt gggaagtgtt gttgatgaaa
    25621 ttgggaaata atataataat tggaattgat actagctgct atactacttc tatagcagct
    25681 atctctttag ataagaaagt tatattcaat gaaaaaataa tgttagaagt aagggataat
    25741 tcaaaaggtt taaggcaaag tgaagctgta tttcaacata tcaataattt agggattctt
    25801 agtgatagga taaaatcttt taaagataag tttaatgtag aaggagtttg ctcatcaaaa
    25861 aaaccgagac ctgttgaaaa ctcatatatg cctgtattca atgtaggtca taattttgga
    25921 aaattattgt ctagtatata tggttgtagg ttttatgaga ctactcatca agagaatcat
    25981 attgaagcaa gtttattaaa tagtaaatta aaaaataata ataaatttat ttctgttcat
    26041 atgtctggtg gtactacaga gatactttta acaagcaaac aagatagtca tcacaatgta
    26101 tgtgatacta atttaggtaa aattgccaaa ataagtatta aaaaagatga taaaagtaag
    26161 ttatacaata attttggata taatatagat ataattggag gaagtaaaga tattagcttt
    26221 ggtcaactca tagatagagt aggaattaag cttggatata aatttccttc aggaaagtat
    26281 ttggatgaaa atgctttaaa ttgtaatctt aaaatagaaa gtggtctgaa aacttctgta
    26341 agagatgggt atatgaattt atctggatta gaaaatcagg taaataagat tataaatgat
    26401 aatggagata atactaatca aaaagaatac atatctaaat tagtattaga ttcagtagtt
    26461 agaaatatgt ttaaatcttt agtatattta tgtgaaactt ataatgtaaa tgaagtagta
    26521 tttgctggtg gagtttctgc aagtaagtat attcttagag aattaagcat gaagttaaga
    26581 aaaaagcata tagaagctta ttttacagaa ccacaatatt caactgataa tgctgtcggg
    26641 tgtgctataa taggattgaa taacttttta ggagaaagag tatgaaacta agagctttag
    26701 atataagtga agcaaactca tatattaaaa gaattttaat aaacgaccca atactttcta
    26761 atcttaaagt taaaggagaa atttctaatt ttaaggttca tagtagtggg aatgtatatt
    26821 tatcacttaa agatgaaaca tcaaagttaa actgtgtaat ttttaaaagt aattttaatc
    26881 gcaatttaaa attagataat ggtgtaaaaa ttatagctaa tggatatata tcagtctatg
    26941 aaagagatgg tgcgtatcaa ttatacatta atgaaattga aatagaggga ataggaaatt
    27001 tacacataga gtttaataga ttaaaggaaa aacttaataa agaaggatta tttgacccta
    27061 aatacaagat acctatacct aaaatgccaa actcaattgg cgttataaca tctccaacag
    27121 gtgctgttat aagggatata ataaatgtaa taaaaagaag atatccgaaa gttaatataa
    27181 agctttatcc agtaatggtt caaggagata aatcagctga agaaatctgt gaagcaatta
    27241 gatttttcaa tcatatgaag aatgttgata cacttatagt tggtagaggt gggggttcaa
    27301 tagaagaact ttggtctttt aatgatgaaa tggtagcaag agaggttttt aattctcaaa
    27361 ttccgataat atcagcagtt gggcatgaaa cggattttac tatttgtgac tttgtgtctg
    27421 atatgagagc cccaacgcca tcagcagcag ctgagattgc tactccatca ttggatgata
    27481 taaactataa acttggaaac ataaaaagta ggatgagtaa gtctcttaca aatcaaatag
    27541 agctagacca atataggtta gaaacagtat ttaataagat aaataactat ttagattcgt
    27601 acacaataaa agataaagtt atacaattag acaaaatata tgataaaata atttttggaa
    27661 tagaaaataa tttaaaatta gaagatgaaa aattagtaaa aattggagca ttactccata
    27721 atttaagtcc attagctact atggatagag gttatagtat aactcaaaaa aatggaaaag
    27781 taataaatag tataaaagga ttaaaaataa aggatagtat agatatagta ttaaaagatg
    27841 gaaatttaga atgtatgata gataaaattg aaaataaaga gggatagtat gaatttaacc
    27901 tacgaagaag cttataaaag attagaaagt attttaagtg aattagaatc taaaaatgct
    27961 agcttggatg aatctttaag cctatatgaa gaaggtataa gcctttataa acattgtaat
    28021 aagcttttag atgatgctaa attgaaaata agtaaattta atcaattagg aatagaagaa
    28081 gactttaaaa tagaggagga ataaaattgg aatttaaaca atgtctaaaa gaaaaagcaa
    28141 gttttgtaga aaaagtactt aaagaatata tgcctaaaga agaagggtat caaaaaactg
    28201 ttattgaagc tatgaactat agtttaagtg ctggaggtaa aagattaaga ccaatactta
    28261 cattggaggc ttgtaaaata gttggaggaa atgaagatga agctattcct tttgctattg
    28321 caattgaaat gatacataca tattcactaa tacatgatga tttgccagct cttgacaatg
    28381 atgatttaag aagaggaaga ccaacaaatc ataaagtata tggagaagct atggggattt
    28441 tagcaggaga tgctttgtta aactatgctt ttgaagtaat gcttgcaggc tcaatcaata
    28501 aagaaaatcc agaaaagtat ctaaaagcta taaatgaaat tgccaaaggt gctggtatat
    28561 atggaatgat aggtggtcaa gtagtagatg tagaaagcga aaataaacaa attgaaaaag
    28621 aaaaattaga ttatatacat atgaataaaa ctgctgcaat gatggtaggc tgtatgagag
    28681 caggagctac tataggtgga gcaaattctg aacaaatgga agaaataact aaatatgcaa
    28741 aaaatatcgg attatcattc cagatagtag atgatatact agacatagta ggagatgaag
    28801 ctaagttagg taaaaaggtt ggaagtgata tagaaaatca taagtcaaca tacccatctc
    28861 ttttaggttt agataaatct aaagaaattg cacataattt gattgatgaa gcaaagaaaa
    28921 gtatagaaaa attatctgat gatgtagatt ttttaaaggg attggctgaa tatataatag
    28981 atagagaata ctaaaatata cagctaaaat cgaggaggga aaaatggatt ttttttcgga
    29041 gatttttaac aatggggctt tgggaataag tctgattgct tgtttcttag cacaatttat
    29101 aaaaatattt actggtaagg aaaaaagaat tgagttatca agaatactta tttcaggagg
    29161 tatgcctagt tcccatagtt cttttgttac aagtttagct acagtggtag gtattgaaaa
    29221 agggtttaat tctactgatt ttgctataat taccgtactt gccttaatta taatgtatga
    29281 tgcagcaggt gttagacgag ctgttggtaa acaagctact atattaaatc aaatggtggc
    29341 agatatacag catggaaagc atatagagca gaagaaatta aaagaattaa taggtcatac
    29401 accactagaa gtttggtttg gagctttact tggaatagta acagctttaa tattgatgta
    29461 aattgaaaat ttacagaata aaggtgagga taatatgtat aaatatttag ataaagtaaa
    29521 ttctccaaag gatataaaaa atatgagtat agaagaaatg gatttacttg caaaggatat
    29581 aagaaagttc ttagtaaaat ctgtttcaaa gacaggagga cacttagctt ctaatctagg
    29641 agtggttgag ttaacattag cacttcataa agtatttgat agccctaaag ataagattgt
    29701 atgggatgta gggcatcaat cttatgttca taaaatagtt actggaagaa aagattgttt
    29761 tgtatctttg agacagttta atggactaag tggttttcca aaggagaatg aaagtcctca
    29821 tgatattttt gatacaggac atagcagtac atctatttct atagctacag gtattgcctg
    29881 cgctagggat ataaaaaaag aaaactatag tgttatatct gtgataggag atggttctat
    29941 aacaggaggt atggcacttg aagctttaaa tcaattagga tatatagata ccaatatgat
    30001 agtaatcctt aatgataatg agatgtccat agataaaaat gttggaggaa tgtctaaata
    30061 tctgtcaagt attataagaa actcaacagt tgagaaaatg acagatgaag ttgataaaat
    30121 tttaaatgtt acacaaacag gtgaaatttt atctaagact gcacatagat ttaaagataa
    30181 actaatgtat agcttttctc ctcaggactg ttcatttttt gattcattag gtataagata
    30241 ttatggacct atagatggcc ataatactaa agaactaata gatatattga gaaaagctaa
    30301 acacaaaaaa gggcctgttc ttttacatgt aattacgaaa aaaggaaaag ggtacagatt
    30361 tgcagaagaa caacctgata aatatcatgg agtatcaaag tttgatataa agacaggtgt
    30421 tacatctgca aaagttaagt ctatgtcaat tagtgttgga gaaaaacttg ttgatatggc
    30481 taataataat gaagatatag tagcaataac agctgcaatg ccatctggta cagggttaaa
    30541 cctgtttgaa agtgcatatc caaaaagata ttatgatgtt ggtatagctg aacaacatgc
    30601 cacaggattt gcagcaggtc ttgcaaaaaa tggtatgaaa ccttactttg ctgtgtactc
    30661 atcatttttg caaagggcat atgaccaagt tattcatgat gtatgcataa caaaaaagcc
    30721 agttactttt cttatagata gagctggatt agttggaaat gatggagaaa ctcatcatgg
    30781 tatgtttgat ttaagttact taaattctat tccaaatatt gtagtaatgg ctccaaaaga
    30841 cacaagagag atggagctta tgatggattt gtcattaaaa ttagattgtc cactagcaat
    30901 tagataccca agaggaagta gttattacct agataaggga gaatatggag agattgtact
    30961 gggtaaatat gaggtattag atgacggtca agatacagtc atactttgta ttggaagtat
    31021 ggtaaaacat gctttagagg ctaaagaaat attatcaaga gaaggaataa atccgacaat
    31081 agttaatgct agattcttaa agccaattga tgaaggtatg ttaaaagcat tattaaaaaa
    31141 tcataaaaat gtagttacta tagaggataa tattgtaact ggaggatttg gaagtagaat
    31201 aaacaagttt attatagata atgaatataa cgtaaatata cttaatatag caataccaga
    31261 agaatttgta aaacatggca atatagatga attatatgat tttgtaggat tatcgccaaa
    31321 aagtattgct gataaaataa ggaaattagt tattgagtaa aaatctaatg tagatattgt
    31381 aaattaaaat ttatataaaa tatagaattt atcaattaga ataaatatca agtgtgttac
    31441 ttcaagctac tttagttatc attaaagtag cttttaacag aaaggtaatt gtatgaaaaa
    31501 aagaatagat ttattattag tagaacaagg gtactttgaa agtagagaaa gagccaaaaa
    31561 agcaataatg gctggattgg tttttgttga taatcaaagg tgtgataagg ctggtacaga
    31621 agtaaaagaa gattgtagta tagaagtaaa aggaaatcca ataccatatg tcagtagagg
    31681 tggtttaaag cttgaaaaag caatgaaaaa ctttgatttg actattgatg gaaaggtatg
    31741 tatggatata ggggcatcca caggtggttt tacagattgt atgctcaaaa atggagcaat
    31801 aaaagtattt tctatagatg ttggttatgg tcaacttgca tggaaattga gacaagatga
    31861 tagggttgtg tgtatggaaa gaactaatat aagaaatgtt acaatagaat atacaaagca
    31921 gtttgctgat tttgcgtcaa ttgatgtgtc ttttatatcg ttaaagttag tacttccaaa
    31981 ggcaaaggag ttagtacgtc atgatgggga agttgtcgct ttaattaaac ctcaatttga
    32041 agcaggaaga gaaaaagtag gtaaaaaagg agtagttaga gaaaaatcta cacatataga
    32101 agttataaaa atgatttctg atttctcagt cgaaaatgga tttgagattt tagggttaga
    32161 tttttctcct attaaaggtc ctgaaggtaa tatagaatat ctaattcatt tgagaaatgg
    32221 aaatgaagga tatgaatttg atggtgagac atacaataac aaaatagtag aagttgttga
    32281 agcttctcat aatttagaca aataggttaa aagggggctt agatttgatc ctcgaattat
    32341 atatgaaaaa ttgtgcctta gttgaagaac taaggttgaa tattgataaa aacttaaata
    32401 tacttacagg tgaaactggt tcaggaaaat ctataataat agatgcactt ggactttgtt
    32461 taggtgataa atatgatagg tcttttttaa gaaaaggaac agataaggga cttgttgagg
    32521 ctgtattttt ttcagacaat agatatctta aaaaaatatt agaagaaaat gatataagta
    32581 tggaagatga taatttattg gtaataacta ggttgatata ctcagatggt aagagtactg
    32641 ctagagtaaa tggaaggact gttaaagtgt ctcttcttaa agaaattgca tctacactta
    32701 tagatataca tggtcaacat caaaatcaag ctttgttcaa taaagatact catttaaaat
    32761 ttctagacct ttttggagaa aatgaattgg aagagtttaa aattgcttat aaaaatgtgt
    32821 accataagta tagtgaagta aaaaaagctt taaattgctt gacagaaaat aaagatgaga
    32881 tgcaaattca acgagaaata gatttattaa gatttcaaat aaatgaaatt gaagctgcaa
    32941 atctaaataa gaatgaatat gaagatttat taaaacaaag agaagtttat agaaatagtg
    33001 aaaagatata taataatcta aattcgagtt atagcaagtt acataatggt gagtataatg
    33061 ttattgacct aataggtctt gcatctaagg aacttaatga catatctaaa tatgacagtg
    33121 ttttaagtga atatagtgat actgtagaaa gaattatgta tgagttacaa gacatatctg
    33181 gtgagataag aaattacaaa gataatatag actttgaacc ttatgagcta gagcagattg
    33241 agcttagaat cgacgaaatt aataatttaa gaagaaaata tggagacagt atagatgata
    33301 tatttgagta ttatggaaaa attaaagata gattagatga aatattaaat agagatgaaa
    33361 gagttgaaca gttaaaaagc aaactgatga atatagaaga agatttaaaa ataaaagcca
    33421 gtaaattgac taaagcaaga atagaagtag caactacttt agaaaaaata cttcttgatg
    33481 aattaaaaag cttaaatatg aaaaatgtaa tgttcaaggt taattttgaa aaaggttcat
    33541 ttactttaga tggagtagat gatattgaat ttatgatatc ttttaactta ggagaagata
    33601 ttaagcctat atataaagtt gcatcaggtg gtgagatgtc cagatttatg ttagcgttta
    33661 aaaccatatt ggctgatata gatgatattg atacattagt gtttgatgag atagatactg
    33721 gaataagtgg gatagcagca cagatagttg gtgagaaatt gagtgatata gcaaagaaaa
    33781 aacagataat atgtataact catttacctc aaattgctgc aaatgcagac actcattatt
    33841 gtatagagaa agatacttca aataatagga cgtttaccaa tgttagtaag ttaaatgaat
    33901 ctcaacgaaa aaatgaaatt gccagactta tagcaggtaa caatataaca gaaaaaacta
    33961 ttgaacatgc aagtgaaatc attgaattgg ctaaaaaatg ttagtgaaaa acaagcattt
    34021 taataggtgt aaagaatttt tatagaaatg ctttacacct attttttatg atgaaattat
    34081 tttaaaatat ctagtgccta tattgaagaa aagtaggttt gaaaatggaa tgaactttgt
    34141 ataaatttgt aactttgaaa tttctaaatg cttaagtata atattattta ttaaggtagt
    34201 agtgagggga ggcataaaat gaataaaaaa gatactatgc acttaatttt tataattgta
    34261 atttttattt tattatggta tattgtggta gcagtaagtg agattaataa aaatattgaa
    34321 agttgtagta acaaattaga ttatttgtca caagagctta tgagtactaa gtcggatatt
    34381 agtaatacta taaatgaaga aatgtcaaaa agttatataa caaaaagtat tgacttaaaa
    34441 gtaaaaaaaa tcgagaaaaa agaatgtact attgatgtag atgttcaatt aagtaaactt
    34501 ggaaaaaatg gaaaagtatt ttttatgtat aaagaagata gtgataaatg gaatgaaact
    34561 gagatgacaa aacatgggga attatcatat gcatgtgaaa taaagataaa tacaggaagt
    34621 gaatatgatt ataaagtagt tacaagtgga gatatatctg aaagttctga tgtacaaaaa
    34681 ctgactaaat ctgattatat gcctgaacaa cctatattta attctgggat aagagataat
    34741 agagaatact ttattgaaat agtagaaaat agtaatcttt ttaatcatga gagtgaaaag
    34801 tcaaaaaata aagcttacga taatatcagg ttagaaaaag tagatattat tgtaaatgaa
    34861 ggaaaaaaag acactatata caaagcccaa ttagctgaag gcttagatga tggcaaaact
    34921 aataattcaa atagaaatca agtgaattat gaagtaagtt ttcctaaaag ggatattgat
    34981 gacataattt atattaaagc taaacttaca tacaataatg gagtagaata tacaaaggat
    35041 ataactgaag atataactat gggattacaa gatttagaaa aataaataca tatttaaata
    35101 aatattcaaa tagatttgtt cacaaataga gtataaataa aactgtagta gttttactta
    35161 tactctatta aaaaattata attttaattc catatatcta gccccttcaa ttggattata
    35221 agtataaagt tctatatcat aaaaaccaaa cttttcatat aatccttgtg cacttttcat
    35281 gcttggaaga gtatctaatc tcatgtgtgt atatccaatt tttttagctt ctacaatgat
    35341 ttcttccaat agtatttttc ctatttttaa tcctctaaat tgatttctta catataatct
    35401 ttttaattca catattttac cttcaagttt ttttaaagca acacaacctg ccaaattttc
    35461 atcaacaaat gccaatatca atgagcctga aggtttttta tattttcctg gaagtgtttt
    35521 taattcatta ttaaagtctt gaaaacataa gtctatattt agagaatttg aatattcagt
    35581 aaatagaagt tttacgtttt caagattttc taaatctttt tcttcaacaa attgtaaagt
    35641 tatattttga gccattttat ccgccattat ataaacatgt ttatataatg acttcacctc
    35701 cttgatatat gtatattttt cttaatatca attagatttt aataccatta ctttttcacc
    35761 accatagtca agctctccat taaacttaaa tccaaaatct ttataaagct taatagccat
    35821 tttattgtct tcgaatatac taagatatag ttcatcacag ttatattcat ttttaagatg
    35881 atttacaaga aaatctaatg atgcttttcc acatccttta ccttgatatt ttgaatcaat
    35941 cataaatcta tcaagccaaa ctctatcatc ttctaaacga ccatacatag caaatcctat
    36001 taaagaattt tcatcatata ttccaacagg tacccaagct gttataaatt tagattcagc
    36061 aatagaaagt gcattgcttt ctatgtaatc taactgactt ttatctacag acaaactaac
    36121 taaatcgtgc caattattta tgtctgcaat tcttacattt aatttcaaga tattaccgtc
    36181 cttcaaactt tttgttacaa tctaatacta tcatattatg tattaaaaat cacttattaa
    36241 gattttaaat aaactttttg aatgaataaa ttctcaggaa aaaggaatta taaatacata
    36301 ataatacagc ataggagtag atggatatat gaacaaaata aataaaaatt tcaaaaatat
    36361 ttggataata ttaggagctg tatcgatttt taccatggtt ataattttta ataaaaattg
    36421 taatgttaat aaagagactc aaatagaagc ttttacaatt aagaatcatg ataaaaaatt
    36481 tgtatatcct atgggaaata taattggagt aaaagcaaat acagatggtg tattggtctt
    36541 aggatatgag gaagaggatg taggctatat tggaggcata caaataggtg ataatatagt
    36601 aaaaatagat aataaaagga taaaaaatag tcaagatgta tcagagattt tgaataagat
    36661 taaaaaaagt aaagttgaag tgacttttga gagaaaaaat aagtataaaa cagaagtaat
    36721 agagactaaa aaagaaaatg gcaagtataa acttggatta tgggtaagag ataaaatatc
    36781 tggaattgga actatgactt tttacgaccc tagtatggaa aagttcaaag caatcggtca
    36841 tgccataaaa gattcggata ctaatgaact attaaagata aagcaaggct atatatataa
    36901 gccagaacaa ttaaaaatag taaaagctag taatgaaaaa gtaggtaaaa taaaaggaga
    36961 ttttaatgac agcaatttaa tgggtaattt ctcaaataat tcagagctag gtataagtgg
    37021 taatattaca gaaaaccata ataaagagtt taatgtagca aataaagaaa agcaattaat
    37081 agaagttgga agaccgcaag atgtaaaaat aggagatgca gtaattcttt ttgaggataa
    37141 aaacaaaaat ataacaagct atgatataaa aatagaaagt atagtatatg ataaaggaaa
    37201 ttatagagat atggtaataa aagtagtaga tgacaagtta ttggaataca caggaggtat
    37261 cgtacagggg atgagtggag ctccaataat acaaaataat aaaattattg gtgcaataac
    37321 tcatgttttt agagataatc cgaaaaaagg atatggtatt tttatagatg aaatgataaa
    37381 attgtaggtg aggcattaaa aaattttatt attttatcaa ttatctagga ggaatataat
    37441 tttggagtgt cgaatatgct ttagagtaga taattaggaa gcaattgtgt aaaaagttta
    37501 gttttctgta ataagaagat gttttttaat ggggggattt ttagtggaaa aaatcaaaat
    37561 agttttagca gatgacaata aggatttttg tcaggtatta aaagagtatt tgtctaatga
    37621 agatgatatc gatatattag gcatagctaa ggatggaatt gaagcattag acttagtaaa
    37681 aaagacacaa ccggacttat taatactaga tgtaataatg ccacatctag atggattagg
    37741 tgtaattgaa aaattgaata ctatggatat acctaaaatg ccaaaaataa tagtactatc
    37801 agcagtaggt caagataaga taactcaaag cgcaataaat ctaggagcag attactacat
    37861 agtaaagcca tttgattttg ttgtgtttat aaacagaatt agagagctag tttctaatag
    37921 agttacacaa gttgagccaa aacctagacc agttcaagag actcaaatga ctagaagtga
    37981 ttttgttaag aatgtaggaa atatagagac agaaatcaca aatataatac atgaaatagg
    38041 agtaccagct catataaaag gatatttata tttaagagaa gcaataaaaa tggttattga
    38101 taatgttgag cttttaggtg cagtaacaaa agagttatat ccaagtatag ctaaaaaatt
    38161 caatacaaca ccaagtagag ttgaaagagc aataagacat gcaatagagg ttgcatggag
    38221 tagaggaaaa gttgacacaa taaatcaatt atttggatat acggtacaca atactaaagg
    38281 aaaaccaact aattcagaat ttatagcaat gattgctgat aaattaagac tagaacatag
    38341 tatggttaaa taaacaagac ataaaaagta aggcttttta attaaggcat tggctataaa
    38401 tgcgtattac aagcagcgaa acggtataac cactagggtt ataccgtttc gctattttaa
    38461 taaatataaa aattttcttt attatttgct tactatatca atataataat tttattatac
    38521 tatggatata gtatgtgtct ttacaagttg taaactgaca gtggtttatt ttttaatata
    38581 aatattgact ttgatgcagg taaactttgt atttttaagc gtattatgga atatgttaaa
    38641 taaaaaaatg atgaaatata gtattgtaaa tgccaaagat gcaaaacaaa cttaaaacat
    38701 ttattttatt gttaagtaat gctataatat aatgtgattt taataatgat agtggaggtt
    38761 taaatatgag agtcgaggcc cctataaaag tagatcgaaa aaccaaaaaa cttgctaaaa
    38821 gagttgaaag tggggaaata gcagttataa atcatataga catagatgaa gttgctgcaa
    38881 actctttagt agaagctaaa ataaaacttg tcataaatgc ggctccttct ataagtggta
    38941 ggtatcccaa taaaggtcca gggatattaa ctgaaaataa tatactaata attgataatg
    39001 ttggagaaga gttatttgaa gaattaaaag aaggagaaac tatagaagtt gtagatggaa
    39061 agatatatag aaaaggaaaa tttttaggtg caggagaagt tttagacaag tatgaggttt
    39121 cacaccaaat aaaggctgcc tatgagaatt tagctgtaga attggataga tttatagata
    39181 atactataga ttatgctaaa aaagaaaaag gatttatact tggagaagta gaaattccaa
    39241 aagtgaaaac taattatgct aataaacatg tattgatagt tgtaagaggt caggactaca
    39301 aagaagattt aagtactatg ctttcttata tagaagaggt aaagccagta ttggttggtg
    39361 ttgatggagg agcagacgct ttaattgagt ttggatatac tccagatgtg attgtaggtg
    39421 atatggatag tgtaagtgat gaagctttaa aaaaggctag tgaaatagta gtacatgctt
    39481 atacagatgg aagagcacca ggtcttaaga gggttgagga attaggctta gatgcagttg
    39541 tatttcctgc gccaggaact agtgaagata tagctatgct tatcgcctat gagtataagg
    39601 ctgagttaat agtagcagtt ggtacacatt caaatatgat tgattttctt gaaaaaggaa
    39661 gaaaaggtat ggcaagtact tttttagtta gactaaaaat aggttcaaag cttatagatg
    39721 ctaaaggcgt taatttgtta tacagaagta aattaaaaat aaagtacata tgggcattaa
    39781 tagcaacagc attatttcct gtgttggtag ttgcatcatt gtcaccagga gttcaacagt
    39841 tcatacaact aatgcaatta aagtttagag tattattaca gatgtaaatt ttaggaggat
    39901 aaatatgcat attaatatga aatattatat agtcactata ggggctatat ttatagcttt
    39961 gggtataggc atgttagtag gatttaattt aaataataat caacaattaa gtgaacaaca
    40021 agcaaacata ataaatgatt tggatgataa gtttaatatc ttaaaagaaa aaaatgataa
    40081 acttgacagt gacttagcaa gtgtaaatag agattatgaa gaggcagtta attttataaa
    40141 taaaaatgta gataagattt tagctggttc gctgaatggt aaaagtatag gaataatatc
    40201 ggctaatgaa aatgacgatt atacaaaaaa tatagaagac ataataaata aatctaatgg
    40261 aagtattgca tttaatatag tattaaaaga aaatataaca aatccagaaa agttaaagga
    40321 aatgtcaact aaactaggta cagatgtaaa aaatgcaaat gatgcagtta attatataat
    40381 tgacaccctt aaaaaggaag atgcaagtga cattttaaca tatcttcaag aactagatgt
    40441 aataaagttt aactctcttg gaaatacata tctaaaatat gattctgttg taatagctgg
    40501 tggaaatgat gcaaaagaca gtacaaaaca gtttgaaaaa atagaaaaat ttgtagtttc
    40561 aaaacttaaa tcagagaata aatatttagt agaagttcaa aatacaggag ttaaaacttc
    40621 ttatgtagaa ctatattcta aaaacaaagt tgcaactata gacaatattg atgaaggtat
    40681 aggaagtata tctctagcta ttcttctaca acaaggtaat atagttggta attttggtag
    40741 attggatact gcaacttcat tgttgccatc tattaaatag aaataatttt aaggagagaa
    40801 aaaatggatt cttatataag tataataata ccagcttata atgaagaaag tagaataaaa
    40861 tatacattag aaagcatatt ggacattaag caaataaatg aaataatagt tgtggatgat
    40921 ggttcaattg acaatactgc taaggttgta tctgagctag aaaatgaaaa gattaaattt
    40981 tttaagttag ataaaaatag aggtaaagga tatgctttaa attatggtat caaattagca
    41041 atgaaaaatg cagatattat aggttttctg gatggagatt taggaagctc tgctaaagaa
    41101 gttgaaaaat taatagtacc tatattaaat ggtgaggcgg atgttacaat agccaagttt
    41161 cctcctgcaa agagaaaagg aggtttggga tttgtaaaag gtttagctaa aaattctgtg
    41221 tttgagatga ctggtgttga gttagatgca actttatcag gtcaaagaat atttaaaaga
    41281 gaagttttag aaaagtttga tgaaatacct tttggatatg gagtagaagt tggaatgacc
    41341 attgatatat taaagtatgg atttaaaatt aaagaagtat tagtaaatat gactcataat
    41401 gaaacaggaa gaaatttaaa aggttttatt catagaggga aacagtatta tcacataaaa
    41461 aaggttttag gacaaaaaaa gaaagaatgg aggtaatatc ttagtgaaag attatatact
    41521 ttataccatt ttattattaa ctggattatt tggaacctat gctgtaattc cactatttaa
    41581 aaatttattg ataaatggaa atgtacttag accaaactat aaaaaagata tgataccagt
    41641 aagtatggga attgtatttt tgcctatgat tgtaatcaat ggaataatac ttgctttctt
    41701 tactacagaa tttaaggatt tagcgtatat atttatgttt atgtttggta tgatatccat
    41761 gttttttgca gggatactag atgatgtcat tggaaataga gatgtaagtg gtttaaaggg
    41821 gcattttaaa agtttattta aaggaagtct tacaacagga ggttttaaag ctttatttgg
    41881 tggatttgta gggcttatag tttctgttgc tatatcaaaa gacataattg atataatagt
    41941 aaatacacta ataatagctc tatcaactaa tttaatgaat cttttggatt taagaccagg
    42001 aagggcaata aaagcatatt tattcataat ggtaattata tttttaacat tgacaggatt
    42061 tgttcaagtt cttccattac ttatagtacc aaatgtactt gcatacttta attatgattt
    42121 aaaagcaagg gctatgatgg gagatactgg ttcaaacgtc cttggaatat ctattggaat
    42181 gctcatttct tttgggtatc catttaacat tagattagga tggttaatat ttgtagttat
    42241 tatgcatata ttcactgaga aatactcatt aactaagata atagaaaaaa ataaactatt
    42301 aaattttata gataaattgg gaaggtagta ttatgataag caaaagagtg gggattgttg
    42361 aatcaatagt aagtcaaact gaaactctag atgatataag agtaaatata aatggaaaaa
    42421 tacaaagggc atataattat cccaaaatat ctggaactat aaatataggt gatgaagtgg
    42481 ttttaaatac aacagcagta gaactgagct taggtacagg tggataccat tttgtaataa
    42541 ctaatttaaa taatatagaa tctactttaa ctgaaggtgg gcatataatg aaacttagat
    42601 atacacctct tcaaataaaa gtggattctg ttgaggaaca agaaagtatt tatcatgata
    42661 aatttgcgaa ttttaaagga ttagaaggtc tttctgttgt agtagggact cttcatagta
    42721 tgttaactcc atttgcagct tcatttaaaa gaaataatcc aaataaaaaa ttagtatata
    42781 taatgactga tggagcatct cttccaattt atttaagtaa aaatgtggac actttaaaag
    42841 aaaaaaaatt aatagatagt acgataacta taggaaatgc gtttggtgga gattatgaat
    42901 gtataaatat atatactgca ttaattacag caaaagaaat actaaaagcg gatgcagtat
    42961 ttgtcagtat gggacctgga attgctggga caggaacaaa atatggattt acagggattg
    43021 aacaaggctc tattcttgat gccgtaaaaa aacttgaagg aagagcaatt gcaattccaa
    43081 gaattagttt tgctgacaaa cgagaaagac atcaaggtat ttcacatcat agtatgactg
    43141 tatttaaaga aattgtaaat gtaaatgtag acataccaat aactatatat gatgatgaaa
    43201 aattgaactt tataaaagag caaatcaatt taaatggttt agacaaaaag cataatataa
    43261 tttatataga taataataaa acgaaagagg atttagacta ttttaatcta aaagtaaaga
    43321 gtatgggaag aaattatgaa caagatgagg catttttcaa agctgcaagc acagcagcat
    43381 attacttaat ggaggtttaa gatggtatta gaagaaaaaa ctattagtag tgatagggtt
    43441 tatacaggta aagtaattac tttaaaggtt gatactgttg aaattccagg gcaaggatat
    43501 caaaaaaggg agttagtaga agttggtgga gcagtaggaa tagttgcaat cacagatgat
    43561 aataaagttg tactagttaa gcaatttaga aaacctatag aaaagccaat ctttgaaatt
    43621 ccagctggta aactagaaaa aaatgaaagt ccaaaagaat gtgctgaaag agaattaaaa
    43681 gaagaaactg ggtatagtgc aaaaaatatt aagctaatac ataaattttt cacttcagca
    43741 ggtttttcta atgagataat gtttgtatat ttagcaacag gtcttactcc aggagagaat
    43801 aatttagatg cagatgagtt tttagatgtc tatgaaattg agcttgaaga agcatataac
    43861 atggtattaa aaaatgacgt tgaagatgca aaaacatcta ttggattatt attagtaaaa
    43921 gatatgttta aaaattaata tttataaaat gaataaccct ttgtcctaaa gcatattatt
    43981 ttataaagga caagggggaa ttaaattgag aagaacatat agaaaaaatg attttagaga
    44041 attaaataga caaataatta ttataggatt gttgtttatg atgtctattg ttgttgggtc
    44101 ttacataaat aaaatattgc caggttctag taacaatata ttaaacaata taaatcctgc
    44161 tgtagagtat tataatctaa atataagcat aaaagataca gtgatacaaa atttaaaatc
    44221 agatgcaatc tttatgggct caatagctct attaagtcta tttgtagtaa caattccagc
    44281 agtgttggta gcttttgtat taaaagggat gtcaattggt tatacaataa atagttgtat
    44341 attggcatta aaatttaaaa gtataaaaat gattttaata atattattta aaaatttgat
    44401 tattattcca tgtgcaatca tattagcatt aattagttta agttatttta aagaaatggt
    44461 ttatgaattt aaaaagaaaa atagaaaaaa tatgcaattt ttaattaaga ggtatatact
    44521 aaatattata attataatag cactatcatt ggggttgcaa ttaatattaa atactgtaag
    44581 tattggtatt attaagttcc tagctaaata aaggagttta taatggatat tatagaggga
    44641 tatatagatt acataaaaga taaaaaaaaa ttatcagaga acacagtggc atcatacttt
    44701 atggatataa aaaaatatat ggaatatata aatcaaaaaa gcattaaact agtagatata
    44761 gtagaaaatg atattataag ttacttaata aagttggaaa aagataatgt atcaatagct
    44821 acaatagcga ggatgatatc ctctataaaa tcttttcatg attatttatt tttaaatcat
    44881 atatgtacaa ataatcctgc aaaggatata aaaaaaccta aaataaaaaa agaaaatata
    44941 aatatactta cagaagaaga aattgaaaga ctattaaatt ttccaaagtt aacaacacct
    45001 aaattgatta gggacaaggc tatttttgaa gtattatatg gtactggtat aaaagtatct
    45061 gaattagtag agatgaatat agaggatatt gacctagata ttgattatat atattgtaat
    45121 tcatgttgta aaaatcaaag agtgatacca ctttgtgata ttacaaaact ttacttagaa
    45181 aagtatctaa aagaagcaag acctaaaatg gctgtagaag gtgaaaaatc attattcgta
    45241 agttcattag gtcaaaggtt tacacgacaa ggtctttgga aagtcataaa aaaatattct
    45301 aatctagcca atatagataa aaatataaat cctacaatgc ttagacattc atttgctatt
    45361 catttgttaa atgaaggtgc taacattgct gttgtaagta aaattttagg aaatgttaat
    45421 ttatctagtt tgcaagtata tttaaatcat atagataaaa acgtgagaag agaaataaag
    45481 gaaaaacatc ctagaaatga tgttgatgta gaattacaaa aagcagaagc taaatagact
    45541 atatagcaaa ttttataatt taaaaggagt atatttatat gagcagagta atttggattg
    45601 taattgatag tgttgggata ggagcattac ctgatgctga aaaatttggt gatagtaagg
    45661 atgtaagtac ccttggaaat atatttaagg aatatccaga tattcagatt cctaatatga
    45721 gaaatttagg tataggaaac atagatggta tagatttttt tgaaagtata aaagaaccaa
    45781 taggttgttt tggaaagtgt aaggaaatgt ctcagggaaa agatactact acaggtcatt
    45841 gggaaatgac tggtataata gttgacaaac catttaagac atttgaacat ggattctcta
    45901 aggagataat agaagagttt gagaaaaaaa ctggaagaaa agtagtagga aataaaccag
    45961 cttcaggaac tgtaataata gatgagtatg gagagcatca aataaaaact ggagatgtaa
    46021 tagtatatac atcagctgat agtgtatttc agattgctgc taatgaagaa gtaattcccc
    46081 tagaagaact ctataatatg tgcaaaatcg ctagggaaat aatgatgggg gataatgcag
    46141 tagctagagt aattgctaga ccattcatag gtaagaaaaa aggtgagttt gtgaggactt
    46201 caaatagaag agattattca ctagacccat ttgaaccaac agttcttgat aatataaaag
    46261 aatcaggact tgatgtttta gcagttggaa aaatagaaga tatttttaat ggaaaaggaa
    46321 ttacagatgc tatccacact aaaagcaata tggatggagt ggatgaaact ttaaattata
    46381 tgaaacaaga taataaaggt ctaatatatt caaatctcgt tgattttgat tctaaatatg
    46441 gtcatagaag agacccagaa ggatataaga aagctcttga agagtttgat agtagacttc
    46501 ctgaaataat ggctaatatg agagaagatg atattttaat aatcaatgca gaccatggaa
    46561 atgacccaac atataaaggt acagaccata caagagaata tatacctgtt atgatttatg
    46621 gcaataagat taaaaaaggt tttaatttag gagtaaaaga tacttttgct gatattggag
    46681 caactgttgc agatatacta aatgtaaagt tgcctaaaca tgggtcaagc tttaaagaag
    46741 atttatttta aactataaaa tgataaaaac ttagcttaat aggatggaga gattggaatg
    46801 tttgaaaaga tagcacaaag tagtaaattt ataaattcta aaagtaatat aaaacctaag
    46861 attggtttga tattaggttc tggactaggt gatttagcaa atgatataga agaccctgtc
    46921 acaattaaat atagtgaaat tccaaacttc cctgtatcaa cagtagcagg acatgctgga
    46981 caacttgtaa ttggaaaact tgaaggaaaa gaagttattg ctatgcaagg tagatttcat
    47041 tactatgaag gatattctca gaaagaagct acttttccag taagggttat gaaagaatta
    47101 ggagtcgaga ttcttatagt aactaacgct gctggaggcg taaataaaga atttaaagca
    47161 ggagatttga tgcttataag agaccatata aactttagtg gaagtaatcc attagtagga
    47221 aaaaatgatg acagatttgg tgctagattt ccagatatgt cagatgcata ttcttctaaa
    47281 tatgtagatg tagttaaaaa ctgcgctaaa gaatgtaata tagatgtcaa agaaggcgtt
    47341 tatatgtttt ttagtggtcc aaactatgaa acaccagcag aagtgagaat ggcacaaatt
    47401 ttgggagctg atgctgtagg tatgtctact gttccagaag tcatagtagc ttctcactcc
    47461 aatataggag ttattggtat atcttgtata acaaatatgg ctgctggcat cttaaatcaa
    47521 ccactaagtc atgaggaagt aatagaaact actcaaaaag ttaaatcaga atttatgaat
    47581 ttagttaaaa caacggttaa aaatttataa gttaaagctt attatatatt ttttgaggaa
    47641 gtttataata aaatagttaa tgtttaattt gaaaagaatt aataaaaagc tgtcttgata
    47701 tagaaagtta tttctaataa aggacagttt ttttataata ctacaacatt tgaaagtgtt
    47761 ttaaagttta atatttattt aaattattat agattagaat ggagatttca attatgagaa
    47821 tgtatgatat tataaaaaaa aagagagata acttagagct tagtaaaaaa gagataaact
    47881 actttataga aaactattca aagggagata tacctgacta tcaagcttct gcactattaa
    47941 tgtcgattta tttaaataag atgaataaac aggaaactgt acatcttaca gaagcaatga
    48001 tgaactctgg agacatgata aacctgtctg aggtagatgg aataaaggta gataagcata
    48061 gtactggtgg tgttggagat aagactacca tagctcttat acctttggtt gcttcatgtg
    48121 gagcaccagt tgcaaagatg tcaggtagag gtcttggtca tactggtggt actattgata
    48181 aattggagtc tataccaggt ttttcgacag aaatggagat aagtaaattt attgattctg
    48241 taaataagtc taaaatagca gtttgtggtc aaagtgcaaa ggtagcaatt gcagataaga
    48301 aaatatatgc tcttagagat gttacagcaa ctgttgataa tatatcattg atatcatcaa
    48361 gtgtaatgtc taaaaagtta gcttcaggag ctgatgcaat tgtgttagat gtaaaaactg
    48421 gtgatggagc atttatgaag acattagaag agtcttttga gttagctaaa tctatggttg
    48481 atataggtac tggtatgaat agagatacaa tagggattgt aacagatatg gatgaacctt
    48541 taggttttgc agtgggaaac tctttagaag ttatagaagc aattgagaca ttaaaaggaa
    48601 atggccctaa agaccttgtt gagctatgtg aagtattagg agcatatatg ttggttttat
    48661 caaaggtagc acatgatttt gaagatggtg ttgaaaagat aagagaatca ataaaatctg
    48721 gtactgctat acaaaaactc aaagagttta tagagaatca aggtggtaat aaagatgtag
    48781 tagatgatta ttctttattc aaaaaatcaa agtataaata tccagttaaa tcaattaaat
    48841 caggttatat aagtaaaatt aaagctgaag atgttggtgt atcagctatg attcttggag
    48901 caggtagaga aactaaagat gatattttag atttatcagc agggataatt ttagaaaaga
    48961 aagtaggaga ttatgtaaat gaaggtgaag ttttagctta catgtattat aatgatgaac
    49021 aaaagctttc attggcaaag ggaagattta ttgattccta ctctattgta gattcaaaaa
    49081 tagaaaaaaa taaattaata tatggtattg taactaaaga agagattaaa aagttttaga
    49141 aaattttaga aaagtgatta taaaaggcct aacatgtcaa aaataatgtt aggtttttta
    49201 ttttttgata aactataaat tataccaaaa atatatattt taaaacattt tttacaatat
    49261 aaataagttt attctacaag atgattgaaa attaaagtat ctagttttat aatagaaaat
    49321 ggataaatat acataaggag tagattatat tatgaacttt aaagaaaata gattgaaaat
    49381 agcagtatta ataattgtta ttttgattat cttagcaggt atatttgtgt ttatacaaat
    49441 aggtccttat gataaaaata acaaaaaaga tgtaattatt gacgttccaa gtggagcatc
    49501 tgttggaaaa atatctgaca tattatatga aaataaatta ataaagaatg aactattatt
    49561 taaacttttg gtaaaggtta gcaataaagc tccgtctata aaatcaggaa catacttact
    49621 taatcaatcg tattcaaaca atgatataat aagtctttta gtttcaggta aaatatatca
    49681 ggatggtata aaagtgacta ttccagaggg agctacatct aaagaaatta tagcaatgtt
    49741 agtaagtaaa aatttaggag ataaagctac ttttgaaaat ttaataaaaa aacctcaaga
    49801 attttatgat aaatttccat atttgaagga agatggaata acctctttag aagggttctt
    49861 gtatccagaa acttattatt ttaattcaaa gaaacaatca gaagaagata ttttaagcga
    49921 aatgttaaaa gtatttgaca gtaaatacac ggacaagttt aaaaagaaac aaaaagaatt
    49981 aaatatgact cttcaagaag taatggaaat ggcatcaata attgagaaag aagctgttct
    50041 tgacaaagac agacctataa tagcaagtgt gttttataat agacttaagg taggtatgcc
    50101 tcttcaatca gatgctacaa tacaatatat atttgaagag agaaagaaaa ttgtaacata
    50161 tgatgattta aaaattgatt caccatataa tagttataaa aataagggat tacctcctac
    50221 accaatatca aatcctggta taaaatctat tgaagcagca ttatatccag agaaaacaga
    50281 ctatttatat tttgtagcta agattgatgg tggaaataat tatagtacaa actatcaaga
    50341 ccatttaaaa tacgttaaag aatataaaga agcaagggat aaacaatcaa aagatacaaa
    50401 agcaacaaat aaagaaaata caaaaaaata aaccatgatt ataaaaagtc taacagggta
    50461 agaataatgt tgggcttttt tattgaaaat tgttattctt agatttataa taaagaaagt
    50521 gtaaatatat ataacaatat gaatttaaaa aataataaat taatataaaa cttgaatatt
    50581 tattatttta gggagtgttt ttatgagtaa tatagttaat gatttggttg aagattatat
    50641 aagagtgaca ttaaaagaaa aagaaggatt tttaaaagat ttagaaattt atgcagagga
    50701 aaatagtgtt cctataatac ataaagaagt ttcagattta ttaaaagtct tgttaaaggt
    50761 tcaaaaacca aagagaattt tagaagtagg atgtgcaatt ggttattctt ctattttttt
    50821 tgcaagtatt ataggaaaag atgcagatat aataactgtt gagagaaatg aaaaaatgat
    50881 agaaaaagca aaagaaaaca taaaattagc tggatttgac aataacataa ctatactaga
    50941 aggagatgca gaagaaaaac ttagtcaagt ccaaggtgaa tttgacctta tatttataga
    51001 tgcagccaaa ggtcaatata agctattttt tgatttagtt atagataaat taaaagatgg
    51061 gggactttta gtatctgata atattttgta taaaggtatg gttgctcatg atgattttgt
    51121 tgtaagaaga aaaaagacta tagttaaaag aatgagaaat tatttagatt atatatgtaa
    51181 ttgtgactat ttaagcacat cattggtacc aataggtgat ggtgtagcac taagttataa
    51241 agaaagtaaa agaggtgatg tagatggaat taaataaagt agaactttta gctccagcag
    51301 gtgatttgga gagattgaaa atagctataa catatggagc agatgccgtt tatataggtg
    51361 gagaaatttt tggaatgagg tctgcagcga agaattttag taaggaagat atggcagagg
    51421 gagtagcttt tgcacatgaa agaggcaaga aagtattcgt aacagtaaat ataatacctc
    51481 ataatgaaga ttttctacaa ttagaagact atttgttgga actagaagag ataggaatag
    51541 atgcagttat aatagctgac ccaggagtgc ttagtgtcat taaaaaagta attccgaata
    51601 tggaaataca tttaagtaca caagcaaata caaccaatta tctaagtgca aacttctggt
    51661 acgagcatgg aataaaaaga gttgtagtgg caagagaatt atcttttgat gaaatatctg
    51721 agataagagc aaaaacacct ttagatatgg atatagaagc gtttatgcat ggtgctatgt
    51781 gtatttctta ttctggtaga tgtttaataa gcaactatat gactggaaga gatgcaaaca
    51841 aaggttcttg tgctcaatct tgtagatggc aatatcattt ggtggaagaa aaaagacctg
    51901 gtgagtattt tccaatatac gaagatgaaa ggggtacatt cttctttaac tcaaaagatt
    51961 tatgtatgat agagtatata ccagagttaa tcaaatctgg tataacaagt ttaaaaatag
    52021 aaggtagaat gaagactgca tactatgtag ctactgttgt aagagcatac agaatggcaa
    52081 tagatgaatt ttacagagcc ccagaaaact ggaagttcaa tccaatgtgg atggaagaac
    52141 taaaaaaagg tagtcataga cattttacat caggttttta cttgaataaa ccaacaacag
    52201 aagaccaaaa ttatcaatca gcatcatatg ttagaaacta tgattttata ggtatagtta
    52261 gagaaacaga agatgaagat ggtcttattg ttgttgagca aagaaataaa atgtgtgttg
    52321 gtgatgaaat agaagttatg ggaccatata aagaaactat gtttactaaa attgaagaaa
    52381 tgtacaatga agaaggagaa gctatagaat cagctcctca tcctagacaa atagtgaagt
    52441 taaagctatc agtaaaagtt ggtaaagatt atatgcttag aaaagttata gaagaaaagg
    52501 ttgaagaata ataaaaaatt gataaaaata gtattagccc cttagaaatt gtcaataatg
    52561 aaattatcta aggggtgatt tcatgtcaaa aaagaagact ccatttttga aaaaagtggg
    52621 aaagagaagc tggtgtatat ttactataat tttaataatt tatagtgttt taatttatag
    52681 gctagttgat atacaagtat taaaaggtga taaatacaaa caaagtgttg aatcacaaag
    52741 cgttgagaaa gtcgagttaa atagtggaag aggaataatc tatgatagaa acaacaagaa
    52801 gcttacagat acaagtaaat ctcaggtatt aattgttgaa aaagaaaaat taaataataa
    52861 ctataaaatt ttggaactta ttaagaaagc tactaagatg aatgatttag atatatataa
    52921 agctgtacaa gagcaattga cacgccctat aatacagatt cagactaaaa atatcgataa
    52981 gagtatgaaa aaagaacttg agaaaaatgg aataatggta gaagaaaaaa ctatgaggta
    53041 cgcaaaagat ggtttattat cacatacaat aggatatata aaagaagatg ataaatcagg
    53101 tcaatcagga attgaaaaga gtatggatag tgtacttaga aattcaaatg aaaagtatat
    53161 aagtgctttt aaagctggag atgcaggaaa tgaaaaatct ctaaacatac taaagggaag
    53221 tgtaaaaact gttgataata aggataaaga tagacatcta aaaactacta ttgattataa
    53281 cattcaaaaa aaattagaac aaatactaaa taaagaagaa aatcctacag cagcaataat
    53341 ctcggaagca tctacaggtg aaattcttgc aatgtgctct agacctaatt ttgaccaaaa
    53401 tgacatatca aaaagtttaa aaggaaaaaa tggggaattt gaaaatagag ttataaaagc
    53461 gacatatcca ccagggtctg tatttaagat ggtagtttta ttttctgcac ttgaaaatgg
    53521 tgttatagat gagaactata cttacaactg tacaggtaag actaaagttg ggaatactaa
    53581 tgaaatactg cgatgtaata aaagagatgg tcatggtttc caaaacttaa gacaagcttt
    53641 ttctaattca tgcaatcctg catttttaga tatagctatg aaacttggaa aagaaaagat
    53701 actcaaatct gctgaaaaat tacatttatt tgaaaaggtt gatattggtc ttgatgaaga
    53761 aaaaattaga gaagctccaa aaaacatatc aataagaaat ttagctatag gtcaagaaaa
    53821 tatagaattt acaccacttc aaataaatca aatgactcaa ataatagcta ataatggaac
    53881 attcaaacca ctatacttat ataaaagtct tgtggacaat aatatgaata caataaaaac
    53941 ttataagtct tcaaaaaaag aagaacttat ttctccttat gtgtgtacac aagttaaaga
    54001 atatatgaag tctgtatcta ggattggtac agctaaagac ctaaaagata ttgaaggtgg
    54061 ttgtggagtt aaaactggta cagctcaaag tagtttaaat aaaaaagcta tagaccacgg
    54121 atggataaca ggattttatc ctgaagaaag acctaagtat gtaataactg tgttagtaga
    54181 aggaactcaa aaaggaaata aatctgcaac acctatattt aaggaaatat gtgaaagtat
    54241 aaaataaatt atgtactata aaatttaagg atatatcgta actttgattt tagatagaaa
    54301 actttgtcta atgatgtacg atatatcctt ttaaaatata gtattaactt tcttgaacaa
    54361 gctctttttc tagtttttta agagcttttt tttcgattct agatacatat gaccttgata
    54421 tatcgagttt ttgtgcaatt tctctttgtg tcttatagcc ataaggagtt aacccatatc
    54481 ttaactggac aatttctctt tctctaggag taagaatttt gtttagttgt tcgtaaagtt
    54541 ttccaacttg aacttttagt tcaacttcat caagaacata gttagcctct gtgccaagta
    54601 tatctaaaag acttatttca ttacacacta ctctttatat gttattggta ttactggtct
    54661 tcatgtaatt tcaaatgaac cattaattca aaagaatcta gtttttgttc tttagactta
    54721 taataaattg ctttatcaat tacagatttt aggagtttat tttttccaag ggaatctgaa
    54781 tcatgataaa gtgataacac agttttaata tcttctatta ttttagaatt gtctttttta
    54841 acagtactca atctattttt tactgtctta attgaatctt taatttcttc agttcttgaa
    54901 cttatattgt tggacctttc aataaatgta tcttcatcat atattccacg ttctaataaa
    54961 tcatataact tatttttttg tttacctaat tcttttaatt cagtttctaa gccctttaag
    55021 actcgttttt gaaattctat attactatct ttattatttt tatctaagtc taaatcacat
    55081 gcttttaatt gatatttttt taccgtgtct tccaaagatt ttaaaatggc agcttcaata
    55141 aattcaaatc gagaactttt attgcaacca ggatggtaac aaattatata gtcgtggtct
    55201 gcatatggtc tatatactaa tggtctacca caatttttgc aaatcactat tcctgcaagt
    55261 ggatttttta tttgattacc atagctgaca tgaccgtttt ttttaagtat attttgagct
    55321 tttttccatg ttatttcact tattaaaggt tcatgctttc cttttgcttc aatccattca
    55381 tctttaggtc ttagcttaac agtttttatt ttatttggat ttttagattt tttatagtcc
    55441 tttttttgcc actgaatgta gccacaatat accttatttt ttattatatt tgtaattgca
    55501 gaattgtacc aattagcacc tgtagcagtt ttaatgccta agttatttag gtattttgat
    55561 attttactac aacccatatc ttcattaata tataagtcaa agatagtcct aactacatca
    55621 gcatccttat ttggtacaag tattctttct tttctacctg ttgttacagc atcatatcca
    55681 aatggagcag aagttcctat gaaattccct tcttcaactg attttattct acctctttgc
    55741 attcttcttg atataagttt taattctttt cttgccataa atgcttcaaa ttctgaatac
    55801 tcctcatcaa attcatctgt taggtcgtat gtttttctag gtgtgatgat tttggtttta
    55861 ctttctttga atgtttctaa tatgatacct tggtctttca tgtctccacg accaagtctg
    55921 tctaagtcca ttactaagac tgcatcatat ttattttctt caacttcttt tagaagttca
    55981 agcattttgg gtctatgtat tatactttca ccagaaacta attcttcttt tatctcaatt
    56041 acatctaagt tttgttcttt tgctagtttt agtagggttg atttatgtct acttaaagtt
    56101 tcaaattcgc cttgtttttc tgcctcttca tcagcacggg attttcttaa gtatatggca
    56161 acactcataa taagtaatca cactccttat gcactattat atagtaaatc aatagagttt
    56221 aaaatataga aaataagcat gtcaaaagtt aatttaactt tcaacatact tattttctat
    56281 aatattaatg ccttataatc ctttaatatc atttagatta gtttttgcat attcattatc
    56341 cgggttaagt tcaagcgcct tattgtaaga ttctctagct ttattaaatt ctgatttact
    56401 cataaaaata acacctctta aattgtaagc atcactagcg tctattttat aagcttcatt
    56461 atttttatct agatattcta aggatttatc aattgacttt aaagcctcat catatcgttg
    56521 taactctata taaatatatg attgtgtata atatgcaagt ggatttttat catcaatttc
    56581 tatagctttt ttgatatcaa tagcagcttt attataatcc ttatcttcat ctttttttgt
    56641 ttctgaccta gcgattttga cataattaga gctaagagct cttttaaagt ctttatgcca
    56701 taataattta tattcattat cttcgattat aaaatatcta tcaaaatttg cagtatcttc
    56761 tttattttca gtgatatact ttatagtatc agtttctttt attttaacaa gatttgtgta
    56821 ctctttatta gaatatttgt atttctctac tttattttct tcaccaagtt tataatcttt
    56881 tagggtttga agtttaaata aagtatcttg atattcttca aatttttcta gactgacact
    56941 ttccttactg tctttactta ataaattata tgctacttcg tagtctttga tttctatact
    57001 atcaaggtac tttttagcta cttctgtagc actttctttt ggagcacatc caaccattga
    57061 tatcataatt aaaaatgata ctaatattgc tgttattttt ttactgatta tcataatata
    57121 atccccctta tattgtctct cactaatttt attttatcac catattctac caaagtcatt
    57181 aatttaagaa tgatattttt cattaatatt atattaagta ataataattt ttaaaattta
    57241 tggtaacatt ttcctgaaaa gtattatata atttaggtga aaatatttaa gagaaggaga
    57301 tattatgaaa attaaaaaat tattaacaat agggttatct ttatctatat ttattgctag
    57361 ttgccctata tctgcaaatg ctcttgataa aattgaatca attaaaggtg cagataaata
    57421 cgaaactgct ggtataattg cagacaaaca aaactatact acagctatat taattaatgc
    57481 agacagtaca atggctgatg gattaagtgc aagtggactt gcaggagcta taaacgctcc
    57541 aattcttttg actaagaaaa ataacatacc aaatgctaca cttaaaagat tagaaaaggc
    57601 aaaaaaagta tatataattg gaggagaaaa ctctattaat aaatatactg aaactgttct
    57661 aaaaggcaaa ggaatagaga ttaaaagact tcaaggtagt gatagaatta agacaagcta
    57721 taatgttgca aaagaaataa attcaattaa caaagtaaat aaagtcatat tgactaatgc
    57781 ttttaaagga gagcctgatg caatgagtgc tgcacctgta gcagttagag ataaagcagc
    57841 tatagtatta actgatggaa aaagtgttcc atttaataca actggtgtag aaagttatgt
    57901 aataggtggt acttcatcaa tgaatgacaa actagttaag gatactaatt caactagatt
    57961 aggtgggaca gatagatatg atactaacaa aaagataata aataaatttt atagtggagt
    58021 aaaagaattt tatatagcaa gtggtactga tttagtgtat gctcttgttg gttctaccat
    58081 tgctaaaaat aatgctattg tgttagttgg taatgatagt aataaaagtg tattgaaaag
    58141 tacaattaaa ttaactgcta taggaaattt gagtgatagt atattacagc agtgtttaaa
    58201 tgtaacaaaa aatataggcg attctaatac tggaagagaa tatacagtag aagatgctgc
    58261 taatgcagtg aaaaaactat taggtgtgaa gaaattttat tacgaaccta attattcaga
    58321 agatgaagat ttaatatttc tactagataa aaattttgat ttttcaggaa aagagtacta
    58381 tgtatttgct tacattaaac agggtgcaga gggtgatgtt agatactgtg tagctaaaaa
    58441 tgatatgagc aaagtttata catatgatgt taatggtaat atgaaagtat gtaatccaga
    58501 tgattataaa aataaaggaa gtataacaga ggaacaagca aaacagatag cattaaaaga
    58561 atgtgctaag agacataaag tcagtatcaa taacttagta gttgatatga tagattttag
    58621 agatgatata tatagtggta atgtctatgc tgttaaaatc aattcaaaaa atagtaatgg
    58681 tacttttggt tggtttttta tagatataga aactgggaaa atttataatt aaaattagaa
    58741 cttttaaaca ataattatat aatttaccat aatatgttat aatattttta gcaagaagat
    58801 ttaacttaca atctatagag tggagttcat gtacaaaaga ttatcctccc aacgattcga
    58861 agggaggtga gttcatggat aactttttgt ttaatgtttt agctagttta acagctagtg
    58921 tggtagttta cttaatcagt aaactattca aaaaagcaaa aagccactct cgcatgaact
    58981 atacccctct taggagacag ttgaaatatg taaaactgtc t
//
LOCUS       DAEQJM010000018        54990 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.018, whole genome shotgun sequence.
ACCESSION   DAEQJM010000018 DAEQJM010000000
VERSION     DAEQJM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54990
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.018"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            29..1309
                     /locus_tag="KRQ43_001438"
     CDS             29..1309
                     /locus_tag="KRQ43_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBH2741801.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKVDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1572..2963)
                     /locus_tag="KRQ43_001439"
     CDS             complement(1572..2963)
                     /locus_tag="KRQ43_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH2741802.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(2974..4194)
                     /locus_tag="KRQ43_001440"
     CDS             complement(2974..4194)
                     /locus_tag="KRQ43_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBH2741803.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4208..4996)
                     /locus_tag="KRQ43_001441"
     CDS             complement(4208..4996)
                     /locus_tag="KRQ43_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH2741804.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(5013..6287)
                     /gene="larA"
                     /locus_tag="KRQ43_001442"
     CDS             complement(5013..6287)
                     /gene="larA"
                     /locus_tag="KRQ43_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HBH2741805.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6405..7118)
                     /locus_tag="KRQ43_001443"
     CDS             complement(6405..7118)
                     /locus_tag="KRQ43_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH2741806.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            7243..8502
                     /locus_tag="KRQ43_001444"
     CDS             7243..8502
                     /locus_tag="KRQ43_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HBH2741807.1"
                     /translation="MKKNKIIAFFAPAIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKHEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFIKKFSRKK"
     gene            8770..9336
                     /locus_tag="KRQ43_001445"
     CDS             8770..9336
                     /locus_tag="KRQ43_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH2741808.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9537..10742)
                     /locus_tag="KRQ43_001446"
     CDS             complement(9537..10742)
                     /locus_tag="KRQ43_001446"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH2741809.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(10845..10951)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11043..11411)
                     /locus_tag="KRQ43_001447"
     CDS             complement(11043..11411)
                     /locus_tag="KRQ43_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HBH2741810.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11463..12740)
                     /gene="obgE"
                     /locus_tag="KRQ43_001448"
     CDS             complement(11463..12740)
                     /gene="obgE"
                     /locus_tag="KRQ43_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBH2741811.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(12851..13141)
                     /gene="rpmA"
                     /locus_tag="KRQ43_001449"
     CDS             complement(12851..13141)
                     /gene="rpmA"
                     /locus_tag="KRQ43_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBH2741812.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13155..13472)
                     /locus_tag="KRQ43_001450"
     CDS             complement(13155..13472)
                     /locus_tag="KRQ43_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBH2741813.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13487..13798)
                     /gene="rplU"
                     /locus_tag="KRQ43_001451"
     CDS             complement(13487..13798)
                     /gene="rplU"
                     /locus_tag="KRQ43_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBH2741814.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(13899..15320)
                     /locus_tag="KRQ43_001452"
     CDS             complement(13899..15320)
                     /locus_tag="KRQ43_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HBH2741815.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLIIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15338..16039)
                     /locus_tag="KRQ43_001453"
     CDS             complement(15338..16039)
                     /locus_tag="KRQ43_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HBH2741816.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16041..17885)
                     /locus_tag="KRQ43_001454"
     CDS             complement(16041..17885)
                     /locus_tag="KRQ43_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HBH2741817.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFI
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18204..19397
                     /locus_tag="KRQ43_001455"
     CDS             18204..19397
                     /locus_tag="KRQ43_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBH2741818.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19609..20691)
                     /locus_tag="KRQ43_001456"
     CDS             complement(19609..20691)
                     /locus_tag="KRQ43_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH2741819.1"
                     /translation="MKKIRKLATKLLIATMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGESVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQEEAILDEVYGNNLRPKIERYEGVPCSLINSSINTIKFTSKNSNLDPS
                     RHTVSVIGFMNTPYGMVALAPDGVPVEYPFEYDKPFSLDFTGKNLSAAELSKKCKNNN
                     VIIKIEIGEIEPNSGRGQVRYARYVN"
     gene            complement(21255..22046)
                     /locus_tag="KRQ43_001457"
     CDS             complement(21255..22046)
                     /locus_tag="KRQ43_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741820.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTNIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(22050..22379)
                     /locus_tag="KRQ43_001458"
     CDS             complement(22050..22379)
                     /locus_tag="KRQ43_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2741821.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(22864..23277)
                     /locus_tag="KRQ43_001459"
     CDS             complement(22864..23277)
                     /locus_tag="KRQ43_001459"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBH2741822.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(23318..24448)
                     /gene="rodA"
                     /locus_tag="KRQ43_001460"
     CDS             complement(23318..24448)
                     /gene="rodA"
                     /locus_tag="KRQ43_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HBH2741823.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(24533..24817)
                     /gene="minE"
                     /locus_tag="KRQ43_001461"
     CDS             complement(24533..24817)
                     /gene="minE"
                     /locus_tag="KRQ43_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBH2741824.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(24835..25632)
                     /gene="minD"
                     /locus_tag="KRQ43_001462"
     CDS             complement(24835..25632)
                     /gene="minD"
                     /locus_tag="KRQ43_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBH2741825.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(25656..26339)
                     /locus_tag="KRQ43_001463"
     CDS             complement(25656..26339)
                     /locus_tag="KRQ43_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBH2741826.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYENESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(26437..29415)
                     /locus_tag="KRQ43_001464"
     CDS             complement(26437..29415)
                     /locus_tag="KRQ43_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBH2741827.1"
                     /translation="MEENKQVDRLKIIKIVMSVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMLTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKMNVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(29427..29915)
                     /gene="mreD"
                     /locus_tag="KRQ43_001465"
     CDS             complement(29427..29915)
                     /gene="mreD"
                     /locus_tag="KRQ43_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBH2741828.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(29930..30823)
                     /gene="mreC"
                     /locus_tag="KRQ43_001466"
     CDS             complement(29930..30823)
                     /gene="mreC"
                     /locus_tag="KRQ43_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBH2741829.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKDMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(30833..31843)
                     /locus_tag="KRQ43_001467"
     CDS             complement(30833..31843)
                     /locus_tag="KRQ43_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH2741830.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(31964..32623)
                     /gene="radC"
                     /locus_tag="KRQ43_001468"
     CDS             complement(31964..32623)
                     /gene="radC"
                     /locus_tag="KRQ43_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBH2741831.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(32668..33252)
                     /gene="maf"
                     /locus_tag="KRQ43_001469"
     CDS             complement(32668..33252)
                     /gene="maf"
                     /locus_tag="KRQ43_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBH2741832.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(33472..34443)
                     /locus_tag="KRQ43_001470"
     CDS             complement(33472..34443)
                     /locus_tag="KRQ43_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HBH2741833.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(34459..35034)
                     /gene="rsxA"
                     /locus_tag="KRQ43_001471"
     CDS             complement(34459..35034)
                     /gene="rsxA"
                     /locus_tag="KRQ43_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBH2741834.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(35049..35642)
                     /locus_tag="KRQ43_001472"
     CDS             complement(35049..35642)
                     /locus_tag="KRQ43_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HBH2741835.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(35655..36224)
                     /locus_tag="KRQ43_001473"
     CDS             complement(35655..36224)
                     /locus_tag="KRQ43_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HBH2741836.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQENNEL
                     RKAVLPEAKEFKEMDKSTYKDLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(36224..37201)
                     /locus_tag="KRQ43_001474"
     CDS             complement(36224..37201)
                     /locus_tag="KRQ43_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HBH2741837.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(37224..38561)
                     /gene="rsxC"
                     /locus_tag="KRQ43_001475"
     CDS             complement(37224..38561)
                     /gene="rsxC"
                     /locus_tag="KRQ43_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBH2741838.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(38777..39721)
                     /locus_tag="KRQ43_001476"
     CDS             complement(38777..39721)
                     /locus_tag="KRQ43_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741839.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(39832..41106)
                     /locus_tag="KRQ43_001477"
     CDS             complement(39832..41106)
                     /locus_tag="KRQ43_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH2741840.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSNQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKSKNNGWYKVKLSSGTIGWVSASYISETNEGTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(41238..41609)
                     /locus_tag="KRQ43_001478"
     CDS             complement(41238..41609)
                     /locus_tag="KRQ43_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH2741841.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(41837..42436)
                     /locus_tag="KRQ43_001479"
     CDS             complement(41837..42436)
                     /locus_tag="KRQ43_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741842.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(42637..42849)
                     /locus_tag="KRQ43_001480"
     CDS             complement(42637..42849)
                     /locus_tag="KRQ43_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBH2741843.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDISIEKLKEVIAELGFELKGIE"
     gene            complement(42922..44637)
                     /locus_tag="KRQ43_001481"
     CDS             complement(42922..44637)
                     /locus_tag="KRQ43_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2741844.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEEARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANINSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEKKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(44637..45191)
                     /locus_tag="KRQ43_001482"
     CDS             complement(44637..45191)
                     /locus_tag="KRQ43_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH2741845.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(45184..45786)
                     /locus_tag="KRQ43_001483"
     CDS             complement(45184..45786)
                     /locus_tag="KRQ43_001483"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBH2741846.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNISIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNSLTHPRIREKIISEIEELR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSKQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(45795..48443)
                     /gene="polA"
                     /locus_tag="KRQ43_001484"
     CDS             complement(45795..48443)
                     /gene="polA"
                     /locus_tag="KRQ43_001484"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBH2741847.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFKINR
                     LEIDGYEADDIIGTVSKKAENNGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPAQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMVFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDTEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETIPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            48762..48844
                     /locus_tag="KRQ43_001485"
     tRNA            48762..48844
                     /locus_tag="KRQ43_001485"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48796..48798,aa:Leu,seq:caa)
     gene            50219..51628
                     /locus_tag="KRQ43_001486"
     CDS             50219..51628
                     /locus_tag="KRQ43_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBH2741848.1"
                     /translation="MIFSSLIFLFLFFPVTLICYYLANPKYKNVMLLLASIAFYAWGE
                     PKYIFLMILSIIVNYIFGIKVSGSKNKKMWVVLSVIYNISILAVFKYSNFFIDNINFL
                     FNTDITIPEVKLPLGISFFTFQIMSYVIDVYRNDAKVQRKLANLALYISLFPQLVAGP
                     IVRYQTVADSIEYREHNWDKFTQGVNRFVVGLGKKVILANQLGVIADGVFNKSAGDLS
                     RLEVWLGIVCYTLQIFYDFSGYSDMAIGLGKMFGFEFLENFNYPYISQTVSEFWRRWH
                     ISLGTWFKDYVYFPLGGSRVSKAKLYRNLFVVWFLTGMWHGASWTFIIWGLYYGILIS
                     VEKAFLEKFLYKMPRIVRHIYLLLIVMIGWVFFRVDDLPAAIKFIGIMFGAGNYPVIS
                     DAFNVFIIEYWYIIVGAILLSTPIVKVVKSLLIKKNKNTLNSTLYQVTNVVFIVSCMF
                     IVIIMLSSSTYNPFLYFRF"
     gene            51644..52846
                     /locus_tag="KRQ43_001487"
     CDS             51644..52846
                     /locus_tag="KRQ43_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741849.1"
                     /translation="MSKKKPRIVAISFLIIVFGFFILNFTLPKKKLSITENRNLAKFP
                     TVENLKKCDFIAKFEEYFNDHFAFRDEMISINTRTQANLNKTKVGNYYLGKDNWILGM
                     FPEILDQKQLSRYEKSINYLSNLSKDMGKNVYFTMMPHKTNMLKHLYPKYVDNMDNID
                     INLKNFKNRLNPDLIKYIDMDEYFLSNYSDKERENLYFKTDHHWTGYGAFEGFKMMAS
                     NMDLGLSKQDLDKHFSSYKKSIITDKKFIGSYNQNIDMLIKENEYVVYMTKDNQDYSF
                     DINGEEKEEKEEKEVYATERDNKEWDYGGAYIRGAKTNILTIKNPKALVDKKILIFRD
                     SYQAPTTLLFADMFKEVEIADPRNINSIYKTYKEIIEESNADIVMFMYNSSGFDSMID
                     SMIDKGIK"
     gene            53047..54030
                     /locus_tag="KRQ43_001488"
     CDS             53047..54030
                     /locus_tag="KRQ43_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741850.1"
                     /translation="MKEVFNVHIMQSQNKKIKQKYYLTKDGWLLGNFAKLLSDYHIKS
                     YSKAINNLSKLNRKKDFYFVSLPHKTNMLKHLYPSGIEGKNNIDINKENLEKQLTDIN
                     FLDIDDYFYRSFTEKEREKFFLKTDHHGNSLGAFEEYKFILDKLDLGLSKSEIDSHLK
                     RYSTRYVNDKVFIGSYNKKMGYPLKKKESISYVEISDANYKYFISNGTKNTEINENII
                     KAKLKDKREWDYGGAYMRGCDCHILKIRNSSSLTNKKALIFRDSYQAPMTWMLADTFK
                     ELEILDPRYIKNIDMTYDEIIKNSNANVVLFMYNSFGFAGMIQEMIDKGIA"
     gene            complement(54480..54923)
                     /locus_tag="KRQ43_001489"
     CDS             complement(54480..54923)
                     /locus_tag="KRQ43_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741851.1"
                     /translation="MKKNMLYLGIVYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GICMIFQYMYWSKPERAVDYEEKIKNQRIEMNDERRVMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
BASE COUNT        17608 a         9814 c         6247 g        21321 t
ORIGIN      
        1 aaataattaa agataaaagg agtattttat gaacatactt ggattaatag ttgaatataa
       61 cccatttcat aatggacaca tatatcattt atctaaatct atagaaaaaa caaatgcaac
      121 acatactgta gcaataatga gtggaaattt tctacaaaga ggcgaaccag ctttatttga
      181 taaatatact agagcaaaaa ttgctgtcga aaatggtgta gacttagtta tagaattacc
      241 aactttattt gcttgtcaaa gtgctgaaat tttttctcat ggtgctataa caattttaaa
      301 ttcactaaac tgcataaatt ctatatgttt tggtagtgaa gaaggaaata cagaaattct
      361 ttataatata gctgaaattt tagcaaatga accaaatgaa tttaagttac ttttaaaaaa
      421 atatttagat gatggcctgt tatttccaac agctagagct aatgcacttt ttgattatat
      481 acatcaagac aaaaaaaata attttataca aaattattca aaggaacaat tatcaaaaac
      541 attaaattca tcaaacaaca tactgggtat agaatacata aaaaacctca tccatttaaa
      601 cagtagtata aaaccattta ctatctccag ggtccaatca gaatataatt ccgaagaaat
      661 tgagagtgat atttgttctg ctactgctat aaggacttca cttaaagaaa atacagacct
      721 ttttcattta aaaaatgtta ttccagaaaa aacttataac atcctaaatg aaaaagtaga
      781 taatggtttt ttacctatgt ttgatgactt cttctttgat attttaaaaa caattatact
      841 tagagatatg gacactttaa aagagtattt tgaagtaaat gaaggcatag aaaacagaat
      901 ctataaagat atctttacat ctgaatttct acatgagcta caattagcaa ttaaatccaa
      961 gcgatacact ttaaccaaaa tcaaacgaac tctaaacaat atattgttag gtattaaaaa
     1021 aagcgacatg caacttataa aaaacataga tactatacct tatataagaa tacttgcttt
     1081 taatgataaa ggtagagaaa ttctaaaaga gataaaaaat aaatctgaaa taaaaataat
     1141 aaacaagttt tcaaatatat cattttcatt agatgatacg atttttaaaa cactcataag
     1201 ttatgatata aaagctacaa atatatataa ttcaatatat tataaaaaca ataaagattt
     1261 agtaaaaggc cctatggatt tttatactca tccaatatat gtaaagtagt tttttaaaat
     1321 aactatattt ataaaaatca ttttattaac tctttattat ataagataca atagtcttac
     1381 tttatttatg tacacatgct tttaggatga caacatcaac ttaaatatta tgttactttc
     1441 taaatttaag taaatattgc catcctaaaa attttacaat ttagcttcag atttaaaagt
     1501 aaagtttaaa atattatatt taaatctaat ttaatatttt ttgttttgta aatattatta
     1561 aattaatatt tctaatatat tttccctgga tttaaaatat ttttagggtc aaaagctaac
     1621 tttatatttt taattaacat catataagca tctgaatttg attcatgtaa gtactctttt
     1681 ttagcatatc ctatgccatg ttcaccagaa acttgaccac taagttctct agatttttta
     1741 tacatatagt caaaagtttc ttttaatctt attttccatg tattatcatc cataccatct
     1801 tttaaaatat atatgtgtag atttccatct cctgcatgac caaaactttt tattcttatt
     1861 tttaatttgt cttgaagctc gtgagtgtat cttataaact ctgctatctt atctcttgga
     1921 acaacgacat cacattcatc catttgtgtc gtagatgcct ttatagcttc taaaaatgca
     1981 cctctggctg accatataga atcgtttctt tcttgtgtat ctgatataaa tacatctaat
     2041 gcaccatttt ctaaacataa attagctact ttttcatatt ccttttctat atcttcagtg
     2101 ctatttccat caaatgtaag taaaagataa gcatctgatg tattatctgg aaacttttta
     2161 cctaaaaatt cttctgctgc caatattaca tctctttcca taaattctat agccgttggt
     2221 attgattttg attttattat tttaggaaca gtttctattg ccattgataa atctggaaat
     2281 ggtataagca aacttatact tttctttggt aaaggaagca attttaatat agctttagta
     2341 actattccta aagtaccttc tgaacctact aataaatcct ttatactata tccagaacta
     2401 tttttaacca cctttccacc tacatttata atttctccat ttggtagtac aacttcaagt
     2461 cctcttacat aatcccttgt aacgccatat tttactgctc tcataccacc tgcattagtg
     2521 tttatattac ctgcaattgt agcacttttt tcacctgggt caggtgggta aaataaatct
     2581 ctatcttgaa catattgacc tattgtcatc aataaaacac ctggttctac tgtcaatgtt
     2641 aaattttcat aatcaacttc aagtatttta ttcattttac atagattaat cattattcca
     2701 ccatttatgg caacagcagc acctacaaga ccagtacctt gacctcttgg tgtgactggt
     2761 atattatttt tatatgcgta tttcattatt ttagatactt gttcagtttc aagtacattt
     2821 actaaaactt cagggtactt ctcaatccct ccaagttcat catgtgaaaa atcttcattt
     2881 atatcacttc caactaatac attttcttct ccacaagtat ctattaaaaa atctatatct
     2941 tttttatcga ttaatttata catttctatc cccctattta gctgctgatg ccatatattt
     3001 ttgattatta tctttgttat tttctatttt ttcaatcaat ttaggaataa tatcataaat
     3061 atcacctatt aaagctaaat gtgctacatc aagtataggc gctttatcat ctttatttat
     3121 tgctactata tagtcagcac cctgcatccc tgcaacaaat tgaactgctc cagatacacc
     3181 acaagttatt atcaatttag gttttacagt tctaccacta agacctattt gttttttagc
     3241 atctatccaa cctgcttcta ttacaggtct tgttcctgcc acttgagcgt ttagcttatc
     3301 agctaattta tatatcatct ccatatcttc ttgttttttt attgctctgc ttgccacaac
     3361 tatcacttca gcttcttcca gaccaacttc tttatttttt tcttttacac tcagtacctt
     3421 aattttagat tttagttctt ttttttctac tttacataaa gttatctttc ctgtagtatt
     3481 ctctattttt tctggtgctg aaaatatttt atatcttaca gtggcaaatt gtggtctatt
     3541 attaggtgtg tttatatgag ccattatatt tccaccaaat gctggtctta tttggtctaa
     3601 atcagtattt gattgaatat caagtattgt acaatctgct gtaagacctg ttctaaatct
     3661 agcggcaagt cttggagcta atgacctacc taatgtagtt ccaccaacta atactatcgt
     3721 tggttttatt ttatctataa agttttctat tgcttttgaa tatggttcta tcctaaaatc
     3781 tttaaattca tcttcatcat atacaaatac ttcatccacc ccataagaaa tcaaattact
     3841 gcacttatct tttatgtctt ttcctacaaa tacacaatac acaggttgtt ttatttttga
     3901 tgccatctca cgagctttac ctataagctc gtacgttaca ggatgtatat ttccattatg
     3961 atgttcaaca tatactgcaa ttcccctcca ttcatcttta ttaatttgta ctttactact
     4021 ctctataaat tcaaatgcgc cttttggtcc acttttgaca cacaacttgc acatcttaca
     4081 gccagcactt atttctacta tacctgactt ttcttctata gccccaaaag gacatatttc
     4141 taaaattctc tttaagtcag ttattttatc ttgatttaca actatctttg acatttatta
     4201 ctccccctta caccaacttt aattcctcta atttatttac aagtgcaaaa cttagttcat
     4261 ctgcatttcc tcttacaata tttttatctg tatttggctt tggaggaaat attcttacaa
     4321 cttgagtagg agaaccgtta agtccatagt tattttcatc tttatcttca aagtcatcta
     4381 agctatatac aggtatttct ctatctttag tattaagttt taatttaaat gaaggtagtc
     4441 ttggttgaaa aatgtctttt tctacagtta ttaaacatgg atattcaatc tcacatactt
     4501 gtaaatcatt tggcatatct atttcaacaa ctatactttc atctttaact tcaattaatt
     4561 ttgtaacgtt agtaacatga ggtatatcta aaaattcagc tacttcaggt cccacctgtg
     4621 ctgtatcacc atcagtagtt tgttttccac aaattattag gtctaccttt cccatcttct
     4681 taataccttg tgatatggta taggaagtag ccaatacatc tgctcctcca aatctcctat
     4741 cacttattaa tgctccttca tcagctccca tcataaaact ttcttcaatt accttctttg
     4801 cctgaggagg acccatgcta agtactttta gattcgcttt cttatcttcc tttattctaa
     4861 gagctgtttc taaagcatat aggtcatagg gattcatttt tgaatctact ccatctcttt
     4921 ttagtactcc tgtagtttca tcaacttcta ctgaagtcgt tccaggaact tgtttaatac
     4981 atgtcaaaat ttccataaag tacactcctt ttttatttaa ctataactga tactccatca
     5041 ggtataacta ctactttgct ctccttacca actatactat tcgccatttc taaagcttct
     5101 ttaaagttaa atgcatgttt catatgcatt ttttttatca tttcaggatt acacttatct
     5161 gttaccatta tcacagtata tttagataat attctcgcta gtatctgaaa ttcccattgg
     5221 tctggaatcg tatctactct atcgacactt ctaattttat ctaaaagttg ttttggagaa
     5281 tctgcatttg ctacattttc ataaaaagat tgacctccat gaccatcatt acatgctgaa
     5341 atcattatta ttactccacc gtctttacaa gtagcttcag ctgctgtcat tcctttaaca
     5401 gattgataaa tattttggtc tagtggatat ccaccatttg tagttacaac aatatcagat
     5461 tttatagaat ttacttttga taactctgtt acaaatctac atcctttagt atgtgctttt
     5521 tcgacatcac cagcaaagga agcaattatt tttttatctt tatctattac aacattcaat
     5581 atgaatgcta actttgcaac tttagctgca tataccatat cctcatgaat aggattatta
     5641 ttcaatttcc cagttcttga attatcacta tctataaagt cactacagtg attgtacatt
     5701 atagtctttg cagatgcgat tcctggaagt acgctttttc tgccacctga aaaacctgca
     5761 aagaaatgag gttctataaa accttctgct atcaaaagtt ctgcctcata tgctagtttg
     5821 tttatatata aatctccacc tgaaggcaat atccctactt tacacataga tttatcatca
     5881 gtagatatat gcataactat atcttcatta tctactattt cttctcccat tttataaatt
     5941 agctcttccc ttgtacttgg cctatgaaat ccagttgcca ctataatctt cacatcaatt
     6001 tctggattaa cattcctaat ccttcttaat ataattggca tagttattct acttggtaca
     6061 ggtcttgtat ggtcacttgt aattatgact acattctttt tccccttaac cagttcttcc
     6121 agagaattag agcctatagg attattcata gattcttcaa ctatctcttc ttgagtctta
     6181 tgttctatat aattatccga ttttgactcc aaaacaccga gaaaacgttc atcaggtatt
     6241 tctaaaatca ttccttgttt tgaatacggt acttttaact ttaccatttt taatctccca
     6301 ttataataaa ctataaaatt ggtatgtggt cataccagtt tcacatttat atgatagtac
     6361 cattatctac catttgcaag aataatttat tttataacaa acttttaatt ttcatttttt
     6421 ctataatttt tacttataaa atccatatgt tcctttgctt tctcacatgc aagttctaca
     6481 tcattttcta caactgcatt gtatatagct tcatgctgtt taagcaatat attttcatta
     6541 aaaggttctg cgattatttt ttctcttgca tcttctataa atccatcaaa taattttgat
     6601 gctgtcataa aaagactttg aattaaataa tttttactta atgttgctag tttactgtga
     6661 aatttttggt ctaataacac cagtactcga ttattatctt ttttattagt ttctactctc
     6721 atttcatcta ttatatgttt caattctata acttcagaag aagttattct ctttgaagca
     6781 agttttgcaa tctcaatttc taggattatt ctaagctcta atatatcttc aagtgtgcca
     6841 ttattaagtt taaaaatcat agataaaggt tctattaaag ttttttctat atttgtacat
     6901 ataaaatttc cttcaccctg tctgctttct atcactccca tagtctctaa taccctaata
     6961 gcttccctta tggaagttct actcacattc atttgttcag acaattctct ttctgatagt
     7021 aatttatccc ccttttttaa ctctccattt agtattttat attgtatttg ctcaattact
     7081 tgttcataaa cttttttact agctatacta ttaaacattt tttcctccaa tatgataatc
     7141 gttgttgtaa tatatatcta ttatatatct taaaccatta cattcatata tttttattac
     7201 ttttaatata atatcttata actcaaattt acaggtgata ttatgaaaaa aaataaaatt
     7261 attgcttttt ttgctccagc tattatagtt ggagttctag ttttagggat tatcctatac
     7321 ccaaatgaag ctataaaatc tgcaagagaa ggcttctcta tatggtctaa tgttttagtt
     7381 ccatcactac taccatttat aattggagca aacttaattg ttgatttaaa aatagtggat
     7441 attatagggt ttatcatcaa tcccataact agatttgtat ttaatgtttc aggaaagagc
     7501 gctttagctt ttgctatatc tacagtatct ggttatccag taggagtaag tttagcttct
     7561 gaatttagga gtaatgggca aatttctaag catgaagcac aaagacttgt gtctttttgt
     7621 tctacatcag gacctttatt cataataggt tcggttggta caggtatgtt ccaaaattca
     7681 aacttaggtt atttaatgat tctctgccat tatctaggaa ctatattggt tggtcttttc
     7741 tttagaaatt atggtaatga aaatcttcca aagacaaaat tggatttaaa aacaaatata
     7801 aaaaatgtaa tcaacattag aaattcaagt gggaatggtt tttttgtttt atttggaaat
     7861 gctgtattta atggagtaaa tacattactt acagttggtg gatttgtaat tgttttttca
     7921 gtagtattta aaatactatc tctttttaat gtaatctcat taatagcatc agttatatat
     7981 ttgcctcttt catttttagg tgttagtaaa gaactctgtc aagcatttgt aagtggtcta
     8041 tttgaaatta ctataggatg caataaagta tctagtataa caagttctcc agaaatttta
     8101 agagcatctt tagctagctt tttgatagga tttagtggat tatccatcct agctcaatgt
     8161 tgtacatttc tatcaaaaac ggacatagat ttaaaattat acatactaag taaatttgcg
     8221 catggagttt tagctgctat ctttatattt atactttatc caattgcaaa ctctgctgtg
     8281 ttggtttcta gctttgctga tacatacaac gttatatata ataatttaat ctggttttat
     8341 tatcttagct attatgatac aattcttcaa attgtagtaa taatttatct aatctcagca
     8401 gtatttattg caaaaaaaca tatgaaaact ttatctacaa atgggaaact aatgcgatat
     8461 aaaaatactt tttttattaa gaaattttca cgaaaaaaat aaaactaata aaacttaact
     8521 aaatacttcc atttttttat tatatttgtc ataattttaa taaccttttt aattagttta
     8581 acagcatagt tatttcatca caatttaata attttattag aaatattttt caaaaaattc
     8641 tccttaatca catatatcac acttgtataa gtttactggg aaatttttcc attatataat
     8701 gtttcattta tattatataa taaataccga cctaaactta ccaaatcaaa ctaagaggag
     8761 tggttgaaaa tggcaacaag acctatagaa atagacgaat ataaaaagat aatggaacta
     8821 ttacatactg gctttactta tagtgaaaat ggcgttgaaa aaagatttag aaaaaatcct
     8881 aaagttgcat tggcactaat gttagaagct aatttaggtc taagaatatc agatatttta
     8941 agattaaaga taggtaattt taaaggtaat atgttggaaa taaatgaaaa aaagacgggc
     9001 aaattacagt atagaccagt taataaaaat ataattgagt ccataaatga acatgcaaga
     9061 aagtataatc ttaaatcaaa tgactactta gtaaatataa agacaaaggc tattcaaaaa
     9121 cagttgagga taatttgtaa acacttaaat ctgtataata taagtacaca tagctttaga
     9181 aagctctatg ctactactca atttgaaaag agtaacaata atttagagtt ggttaaagaa
     9241 cttttaaatc acagttctgt agccactaca cagcgatata taagagtaac tcagcaagct
     9301 attaatgaag ctagtgaaaa tttctttatt ggttaattat aacgtataca tttttctatt
     9361 atcttattaa ttcaccagat attaaaaaag agtgtctcaa aatgaacttt ttagttcatg
     9421 agacactctt tttttataaa atcaaatata tttttattat ttcaatactg gaaaaaaggc
     9481 ttgtctctct attttgagac accctattaa attttcataa ttcttgcata aacatattaa
     9541 tctatcttca ataatttttt agctgattca ctgtaattat ttctttttac aatttccaaa
     9601 actctatcaa tctcatgttc tgactttgca cttacaaaaa tcgccaattc ttcatcatct
     9661 ataatatcat aactatctac atatttatct aaacattcta aaattccatc tttattatta
     9721 tacccaccaa atctaactac tgcactacac tcatcttcta taagtccact taaatccaat
     9781 ttcccttttg aaaaagactt tatatttgaa cttctattat ctattatatc tataatatct
     9841 gcataaacag cacttcctgt tgcacctctt ccagctccct tacctacaaa agaaagttca
     9901 cctactgaat cacctactaa aataactacg ttgaactcat tatctatctt tgaaagcata
     9961 ttattattgt ccactaatgc tggtctaaca aatccactta cttctcctga ttcatactta
    10021 cttctagcaa ccaattttat cttacaattt aatttttttg catattctat atctttttca
    10081 tctattgaag ttattccttc taataataaa tctttccaat atactatttt tccataagat
    10141 aaagtagaca atatagataa ctttctagca ctatcatatc ctaaaacatc tgcatctgga
    10201 ttaacttctg caaatcccaa ctcttgtgcc tgttttaaag caacatcata tggtaaattt
    10261 tcatcataca tctttgataa tataaaatta caagtcccat ttaaaatagc gtttatgctc
    10321 tttatattgt tgccttccag tgattctatc aatggtttta aaactggaat accacctgcc
    10381 acagatgctt caaacttgat gctaacatta tttaagttag ctaattctat aaggtcacta
    10441 cctttttcag ccagtaaatc tttattagct gtcactacat gtattttttt atttaacgct
    10501 cttgttacat aatcaaaagc tggatttaat cctccaatta cttcaactag tatatcaata
    10561 tccttgtcaa atatatcttc tatatcagta gttatcttat caaaatactt cttatacttg
    10621 tgtttttctt tatttttaac taaaattcca acaacttcta tatctctttt tgaagtatta
    10681 ttttctatta aatcaattaa tccacttcct actgttccat accctaatat tgctatcttc
    10741 actgtaacat acccccatca ttttgattat attaaattat ttatatatat aaatatacca
    10801 ataaaaaaag cttgagtata aactcaagcc atatgacggg tttatactca tctttcagca
    10861 taaatgctgc aggatttagc accaatgtat aattaaatat actggttgcc gggcttcaca
    10921 gggccagtcc ctctgccact cttgataaga ttgctaatta aaatttatgt ttaatagtat
    10981 aatacaattt cttccaattg tcactatttt tttaacttat ttccctaaaa ggatataaac
    11041 tattatctaa cagctctttt agttggttta cccttttttg taacattatt atttttagtc
    11101 tttgctttcg cctgttcatg tcctggaaaa agtattttag gctcttcaat attcctcttg
    11161 taaatagtaa atttaaaacc aatagcctgc acaaattcag ctcttaaagc ttcacatact
    11221 gcattagcag tttctttagt atcaagacct gcattttcta atatagtaac ttttactaat
    11281 tctctagttc ttaacatacc atctaattgc tctaagaaac tctctgtaac accttcttta
    11341 ccaatttgtg tagtaggctt taaagtattt gctaaagatc ttaaatacgc cctttgtttt
    11401 ccttttaaca tattctcacc tctataattc tatacttaaa ttatctataa tctatattta
    11461 aattaattgt aaaactcaaa ttctaattca taaattttaa ccacatctcc atcttctatt
    11521 cccatttctc taagcctatc aaaaacacct tgactctcca tagctttttg gaaatattga
    11581 agggattcca tatcatcaaa atttacagaa tacattattc ttctaagtgc tttacctgta
    11641 actacataca caccatcttc aatatctata cttaactctt cttcagtacc aatatcaagt
    11701 tctggtctat acatttcttc ttctgaaact agctccacat cttctacttc ttttagcatt
    11761 ttagaaacat aggctattac ttcatctatg ccttgacgag ttgctgctga cattttaaat
    11821 actgtatatc ctctgccttc taattcactc ttaaacttct caaacttact ctcatcttct
    11881 aatatatcaa atttatttgc aactacaact tgtggcctct ttgaaagctt ttcattgtac
    11941 aatttaagct catcatttat cttgtcaaaa tcttcaatag ggtctcttcc ctctaatcca
    12001 gatatatcta caatatgtat caataccttt gttctctcaa catgtcttaa gaactcatga
    12061 cctaatccta tgccttcaga agcaccctct ataattccag gtatatctgc aagtacaaaa
    12121 ctatctccaa acttagtttg aacaacacct agatttggtg taagtgttgt aaaatgatag
    12181 tttgcaattt tgggtttagc tttagttaca actgatagaa atgttgattt acctacattt
    12241 ggaaatccta aaagaccaac atctgctatc attttaagtt caagagttat ccatctttct
    12301 tctccatctg taccagattt tgcaaaagct ggagcttgtc ttactgcatt tgcaaagtgt
    12361 tggttacctt taccacctat accacctttt gcaactatag ctgtatctcc ttcttttttt
    12421 aaatctgcta atacaagacc tgtagcctca tctcttatta ctgtacctgc tggtactttt
    12481 aatactaaat tttctccatt tttaccagct ctttttcctt tgcttccgtc gccaccattt
    12541 tgagcttgat attttttctg gtacttaaag tccattagag ttctaagccc caaatcaact
    12601 tcaaatatga tgcttgctcc acgaccacca tctccaccgt ctggaccacc agctggaacg
    12661 tatttttctc ttctaaatgc taccgaacca tttccaccat ttccagcctt aacaaatatt
    12721 cttgccttat ctataaacaa attcttcacc tacttaatta aaaactttta attagcatta
    12781 ccaaaaatac cattataaat tcatcagtat tataagaaaa aggagtgcct caacactcct
    12841 tttatgtata ttactcagct attgctactg gatatatact aacttttttt ctcttcttgt
    12901 cttttctttc gaatttaaca gtaccatcaa ctaatgcaaa taaagtatca tcactacctt
    12961 ttccaacatt agttcctgga tgtattttag ttcctctttg tctaactatt atacttccag
    13021 cagttactaa ttgaccatcg aatctcttaa cacctaatct tttagatata gaatctctac
    13081 catttttaga agaacctacc ccttttttag atgctaataa ttgtaaattc atgtttaaca
    13141 tatggagtca ccccctactt ttttaaaatt tttatatttt ttgggtattc ccgtttaatt
    13201 tctttaaccg ctaattgaaa gtgatttagt aataattgtg cgtcttttac atgcgtatct
    13261 ttgactatac actctatatg accttcttct cctactactt tttcaaattc aatcttttgt
    13321 aatttgtcta aagaatttat aactgcaata gcattagatg taactgcagc acatactata
    13381 tcatagccta tttcagcaaa atcagcatgt ccctttaaac aaaaaccttg caacaagaaa
    13441 tcatcattat aataatattt aacttttatc ataacttaac caataactaa gcgtttattt
    13501 tttctacaac tatcttagtg tatgattgac gatgtccttg ttttcttctg taatcttttt
    13561 ttgctttata cttgaaaact ataactttct tagctttacc ttgttcaaca actttagctt
    13621 gaacagatgc tccttctact actggagaac ctaattttaa ttctccatct ttagagcaag
    13681 ctaatacttc gtttaaagta acaacatcac ctgcgttagc ttctaatttt tcaacgaata
    13741 atacatcacc ttcagaaact ttatattgct ttccaccagt ctttactata gcgtacatta
    13801 aatacacctc ctcggcctca aactcgccag tacaaggtac ttcatttgaa gatttaaacc
    13861 tttactgtgc ggcattacaa ttattaatta taaaatattt acattttatt gtcaactatt
    13921 ttatcgaaaa taacattggt tttattgtgc tttaatgtac tatttgcgtt taaagaaatc
    13981 tttatattat atttttcacc aattttatca attatatcca tataatattc ttttatttgt
    14041 tcaaaaataa aatcattaaa ttctaccatt atgtttttgt aaacagtatg ttcacttatt
    14101 ctcataattt ctttttcaat actatctagt atataatgta cagattttat tgtttgttca
    14161 ccatcacaac atggacaaga cattaaataa tacttatcaa tggattcttt ttctctacgc
    14221 ctagcaactt ctactaaacc aagttttgtc atacctaata cttcagcttt tcttttatct
    14281 ttattaaatt cttcttctag gatgtgtaaa atctcctttt gatgcttctt tttatgcata
    14341 tcaataaaat cgattattat tatcccagct atgtctctaa ttataagctg tcttacaatt
    14401 tcttttgcag cttcaagatt agttttataa acggtttcat caagtttacc agttccaata
    14461 aacttacccg tatttacatc tataaccgta agagcttctg ttttttcaat tattaaataa
    14521 cctccactct ttaaccatac ttttttattt aataattttt ctattttaga ttctattctg
    14581 tataaatcaa atacatctct attttcctca agacacagtt tatcaacata agtcttatct
    14641 atacctctta aaatagactt aagttcagag tacttatcat aactattggt aattatagat
    14701 tcaatatcat cattcacatt atcttttaca tatttagttg caaaatctaa agacttatat
    14761 aataatttcg gacctatacc aagtttatat tcttttaaaa tattttcata ctttaatttc
    14821 aactcttcta tatctttctt tatttcatca tgagtgcaac cttgagcctc agtccttatt
    14881 attaatccta gattttcctt atttactgcc ttagtaattt tttttaatct aaatcgttct
    14941 ttttcatcag taattttatt tgatattgta gttctatcat tggaaggtat atagacaata
    15001 taccttccag aaatactaat ctcagtgttt aattttgcgc ctttagttcc tatttcttct
    15061 ttatttatct gaaccaaaat atcctgacca gattttatag tacttccctt ttttaattgt
    15121 aaataagcaa gtttcttaaa tccaatatct acaaaacaag cttctattcc tggtataact
    15181 ttttttacga ttccacgata tatattggat acagtcttct tatttaaatt gtcttcaaca
    15241 aaaagttctg ttaatctttc atcttcaagt actgctgttt tctgggaccc tattagggac
    15301 tcaataacta tctttttcac aacttcacct ctcgagctta cataggagtc actaattccc
    15361 catcttctaa tacatataaa tctcttctca atatatcaac atctaatggg tcaatatcaa
    15421 gttcaaacat ctctaatatc tttggtataa gtatattagt atttaaatta gtttttgagc
    15481 ctgtagctat agtagcagta agagtaatat gttcatcttc taaatttaaa acatcaaagg
    15541 ttcttatcat aggtcttata tctacttcaa ccatcttacc ttttttattc ttttttgtta
    15601 tgattatttc tttattattc ataaagtcaa ttacttttct ttttacaaac tctttcgtca
    15661 taggtctttt caaatctata ttaaacaaat attctccata gtctatcaca gaagaaagag
    15721 aaggtgtttg tctatcaatt tcttttgctt tgataaaatc tatcccatct ggaagttgaa
    15781 ttgatacttt atttaaaaat tcctctactg ataaatcatc ttcttctatt tcaatatcta
    15841 catactcacc ttgactttct gtccctaaag ccaaagcatt gccataactc attttagggt
    15901 gaggattaaa tccttgagaa tgtgataagt ttatttcagc tcttctaaac gctctttgta
    15961 acaatctctg aaggtcaaga tgtgatatat atatcatgtc gccttccttt ttaaatttta
    16021 ctcttattat cttactcata ttagcaaagc ccccttccta tatcatgtat atttattcca
    16081 caaccattgc agttatgtct acaatcagaa gtgatttttt cttttttagc attttcgtct
    16141 tctctaatta agaatttttt actaatacct acatctatat ggtcccaagg aaatacctct
    16201 tcatagtttc tatttctatg tgcataaaaa tctatagaaa gattattctt ttccatagct
    16261 tctttccata tatctaaatt aaaatgttct gcccatccat caaatttagc acctagtcta
    16321 aatgcatcat atataacttt tcctattctt ctatcgcctc tagctactac tgcttccatc
    16381 aaactagtct ttgaatcatg ataattgtat tttatattgt tatttcttaa tttatttact
    16441 aaatgtctct gcttattaat aacttcttct gtagtatctt gaccatgcca ttggaaaggt
    16501 gtaaatggct ttggtacaaa tgtagaagta ctcactgtaa cactaaaact tctctttagc
    16561 tttcctccat ttacttttct ataaatatca ataactttat aagctaattt agctatacca
    16621 tctaaatctt cataagtctc agttggtaaa ccaatcataa aatacaactt aacactattc
    16681 caccccatct caaaagctct ttctgttgca ttttccaaat cttcttctgt aacaccttta
    16741 tttataacat ctctaagtct ttgagttcct gcttctggag caaaagtaag tccagatttt
    16801 cttacttgtt gtattttatc agcaatttcc attgaaaaat tatctaatct aagggatgga
    16861 agcgaaatcc caatattatt agatgcatat tcatctacca aataatcagt caactctgat
    16921 aacttactat aatcactcgt actaagtgat gataatgata tttcatcata tccagtattc
    16981 ttaactaatt tatctaatat ttctttaagt cttttaacac tcttttctct tattggcctg
    17041 tatatcatac ctgcttgaca gaatctacat cctctagtac atcctctaaa taattctagt
    17101 actattctat catgaacagt atctatataa ggtactatta gtttttctgg ataatctaca
    17161 gtctcaacat cttttattat ccttttagta ggatttttag taatcccttc tctattagga
    17221 gttacacttt gaactgtacc atcttcattg tacttgacat cataaaaact tggtatgtat
    17281 actccttcta tgctagatat tttatataaa aaatcttctc tagtcgtttt atttttcttc
    17341 cattctttat actcatttac tacttctaaa ttaacctctt caccttcacc taatattact
    17401 acatctataa aatctgctaa tggttcggaa ttataagcac aaggaccacc aaccattata
    17461 aatgggtctt ccaaagttct ttcttctttt aatattggta tattggctaa atctaatata
    17521 tttaagatat tagtgtatga aagttcatat tgaagtgtaa aagtgacaaa atcaaagttt
    17581 gttataggct ctcttgactc taatgcaaat aatggtatac ttttttctct cattatattt
    17641 tccatatcaa ctgcaggaga atacactctc tcacaaaata catcttcatc cttatttatt
    17701 acatcatata atatatgact ccctaagtga ctcataccaa cttcatataa atctggaaag
    17761 caatgtgcat atcttatcaa ttcactatta ctagtatctt tatgaattga atttatttca
    17821 tttccaagat atctagcagg cttttctact ttttttaaga tttttttcaa gtctacttta
    17881 ttcatttatt aaaattcctc caaacaagct ctttattttt attcttattt ataagtagta
    17941 ttatacacga taaaatattt tctatcaaaa atataactaa aatattgaat ttaaaataca
    18001 tattattcac aaaatagaat agctaaaaat atttaagaat attttctatt aaatttttat
    18061 tgaaatacaa tttttttaca aagtatgata tattataaac ataaaactat tgttttacat
    18121 gacttatcat gacatctttt gtttcattca cctcaaaatt gggtatgtta cttatataat
    18181 gataaatttt aggagggtta aaaatgagta aagtttttga agtaaaaaaa gatatctact
    18241 ttactggcgt agtagatgaa ggtttaaaag tattcgacat aataatggaa actgagtttg
    18301 ggacaactta caactcttat ttaatcaagg acgaaaaaac ggttttattt gacactgtaa
    18361 aggcaaattt taaagatgag tttttaagta atttatcaga ggttactgat atagctaaaa
    18421 ttgactatgt tgtaattcat cacacagaac cagaccatgc aggtagttta aaatacttat
    18481 tagatataaa tcctaatata gaagtttatt gtactaaagc tgctaaacta tacttagatg
    18541 gtcaaataaa tagacctttt aactgtcatg taataaaaga tggtgaaatt ttaaatatcg
    18601 gtaaaagaaa tcttagattt ataactgctc cattcttaca ttgggttgat acaatgttta
    18661 cttacattga ggaggacaag actcttttaa cttgtgatgc atttggttgt cactttgcaa
    18721 gtgttgatgc agaggtagtg aatagtgaag attatctaaa atcagctaaa cactactatg
    18781 attgtatagt taagccattt gctaaacatg ttttaagtgc tgtagataag gtggtaggac
    18841 taaacataga atttgatact atattgactt ctcatggtcc aatgcttact aaagacccaa
    18901 tggctgctgt taaaagatat gttgagtggt ctacagaagc tgttaataca actaatcaaa
    18961 atcaagtttc tatattctac ttatcagctt atagtaatac tttagagatg gctaaaaaga
    19021 taaaagaagg acttgataaa gaaggtgcaa aggctgaatt atatgattta gaagatatga
    19081 cattaacaga aatgcacgat acattagtag tgtcaaaagt aatattacta ggttctccaa
    19141 ctataaacaa aactatggtt aaacctatgt gggatttatt ctctgttata gacccaatgg
    19201 ctaaccaagg caagatagca ggagtatttg gttcatttgg ttggagtggt gaaggtataa
    19261 ctatggctga gactttactt aaatctatgt cattcaaaat gcctgtagaa tctcttaaga
    19321 aaaaattctt ccctagtgaa gagacattaa aagagtgtat ggcatttggt gcagaatttg
    19381 caaaattagt taaatagcca ttaatcacac ataatattat ttaaaataaa tgattttata
    19441 tttaaaaata aattaaaatg gagttgtctc aaaattaatt tttctaatct aattttaagt
    19501 tcaactcctt ttttatttcc caaaatgact aatataatga taaatgcacc ctcaccaaga
    19561 gggtacatta tttataatct tttctatttg tatacttgta tatttatatt aattcacata
    19621 tctagcatat cttacttgcc ctcttccaga attaggttct atttcaccaa tttctatttt
    19681 aataattaca ttattgtttt tacacttttt tgataattct gctgcagaaa ggtttttacc
    19741 agtaaaatct aaagaaaatg gcttatcata ttcaaaagga tactcaacag gtacaccatc
    19801 tggagctaat gcaaccatac catatggtgt attcataaac cctattacag aaactgtatg
    19861 ccttgatggg tctaaatttg aatttttgct tgtaaactta attgtattta ttgatgagtt
    19921 gattaaacta cacggaactc cctcatacct ttcaattttg ggacgtagat tatttccata
    19981 aacttcatca agtattgctt cttcttgatc tgctatcata gtgtgattcc caggtccaac
    20041 tggcgcagaa ggcttagctg gcgtaggttt cttaacagtt ggcgttggat tctgtgtctt
    20101 tactgattca ccaacagctg gataggcttt cttgtcaaat ggtaatgggt gagtaagact
    20161 cttgtatatg atgtctgctc ctgctgattt gttggcatca atatctacat gatacaaacg
    20221 tccatcctca aaacgaataa gattccactg atggtcattt gttgtactat gtacataata
    20281 acattcaatt cccatagcat cacataaagc tttcaagctc ctacacattc cagaacaagc
    20341 acctttttta gtaaccaatg tataagcagt attggctccc tctgctgcgt tccagttaac
    20401 atatgttgtg ttgtttttaa tgtgattata agcaacccta atcttagcat ctgtggtcat
    20461 gttctttgta attttcttgt tcataaagtc tgctgttgct tgtgctaccg aattaagttg
    20521 agcttgtgat aactttggac catatatact gttggttcca gctacatagc ttttcggtgt
    20581 ctttgcagta acatctttag ctgtcatacc ataaactgtt acactcatac atgaggttaa
    20641 aaccatcgtt gcaatcaata gtttagtagc taatttcctg atttttttca tattagcatt
    20701 ctcctttata atatatttta ctttcaattc cctaccatta attaagttca ttttagattt
    20761 aaaatatgga ttatcaacat gtgtgcatag caattcacgt ggtcatagaa tatttagatt
    20821 tcttggaaaa tctgttctat atttcctata tagttcgtac acaatccaac tcacaaacct
    20881 gcatttttga tatcatcaca ataaaatgat aataattaat atattcaaaa atgttggtct
    20941 gtaacaggtt tgtcaatttt ctaattattg gtaatgacga gagtgaggag aattgtcaat
    21001 aatacattta aaattaaaat tgtatacact tcatacattc tcccctaaca acattataca
    21061 gattataatt tgtatattca atacattttt tggaaggtat aattatatca aaatatgtga
    21121 ttatgtatag atacaatcca ctatggagaa atataaaaga aaagagtata acaaacaata
    21181 aaaaataaga tgattcaaat tttattttga aacatcttat ttactctaca aattaaaatt
    21241 atttggtgaa ttatttaatt attatttttt attaaagaaa ttttaaatct taatataaaa
    21301 tacgctatta tacataataa tccaaatgca aatgctactg gaattaacat ctccgattca
    21361 aaataaaaga aatattctaa gaaaatatct ggatttacta tattcccatt cttgtctaaa
    21421 aaatcttttc cattatatcc taaatgctgt ataaaattac ttatgttatt ataatctgct
    21481 tccctctcat ataccatatt agcattcaat ccagaagaac ttaaattagt gtttccatct
    21541 ttcatatcta ttacatatag tctaagagct ttgactttac tatacttatc tttatcaagt
    21601 attttttcaa gttctaactt atattcacca atatttgtca tatcatgtct ttctgccaat
    21661 tgctttattt ctccatcaag ttcttttcct aaattataca tattatgttg taaactatta
    21721 ttgtaatacc acataaatcc agaaattaaa aatgcaatta tacttatgta acctaatact
    21781 tttttaaacc ccattacaat tgatttatgc ctatccaatg ataaagatag ttcttttatt
    21841 atattacata attcatactg catttcatca ccatcatcaa atctttcaat tgctttttta
    21901 catgcttctt cttcatctaa tccttctaat ttaaattcat ttgcagattc tataagatgg
    21961 catctcattt cctgttttaa ttctatagta cttttattgt cacatttttt atatagttta
    22021 tctaaatatt catctattag tttcataaat taatccacct ctcccaaaaa ttgattcata
    22081 acctttttaa taaatctcca ttcttgtttc tttatttcta aaaaatcttt accttcatta
    22141 gttaaattat aatattttct tcttccacct gaactttgtt cattgctata ataagattta
    22201 attaaatttt tagattccat tcttttaagt gcaagataca ttgttccttc ttttaattca
    22261 aactcacttc tttctcttac ttgctttgca atttcatatc cataacaatc tttcttttct
    22321 aatatagaaa caattaatat atcgatataa ccttttaaca cttctttatt taactgcatt
    22381 atgtaccacc gccttttcac ctactactct ataatgtata gtacttatat ttactataat
    22441 aatacatagt actctataat acaaggttta tattctacaa tagacttaaa aataataaat
    22501 agctgtatat tagtatttat agattaaata ctaatataca gctatttatc aaattttaaa
    22561 aataaatttt tgttttatta atgttgtcgt aacaacattt acttggttga aatagtatta
    22621 cctataagtt taaatatata taataataga cttaattcta tttcatatta ttaaaataga
    22681 gtaatagttt aaattctact actctatcta taatctattt cctaattatt taatctcaaa
    22741 tttagctcct catcatttaa atctttcata agatttctac aggtactagg tttattgcaa
    22801 cagaaaaact agggcattaa acacttatat atctgtttct ttagactgta atattaatat
    22861 tttttaaata cgttgacttt tgctttttct aacttctctc catgatagtt ctcctctatc
    22921 aagagctttt ataaatattt ctgctgaagc tagatttgta gctattggaa catgataaac
    22981 atcacaaagt cttattaacg cttgtatatc tgtttcatga gcctgagatg tcaatgggtc
    23041 tcttaaaaaa ataactaaat ctatttcttg tgttactatt aaagaaccta tttgttggtc
    23101 tccacctaaa ggaccagatg ctaatctatt tatatttaat tcagtttcat ccattattct
    23161 ttttcctgta gttccagttg catatagtcc atactttttt aaaattgatt cataacctat
    23221 acaaaatccg accatagtgt ttttcatttg gtcatgtgct actaatgcta tattcatata
    23281 tctaatctcc tcaatttatg tttagatgta tttaaattta gaaatttatt ttctttcttc
    23341 tcatacacac atttagtact aatcctaagt ttgctaaaga tgtcaataac gaacttcctc
    23401 cataacttac aaaaggtaat gttactccag ttactggtat taacgcaacc gtcataccta
    23461 tattttggat tatctggtaa ccaaacattc ccataacacc aaccactatg agggttccat
    23521 aaaaatcttt tgcatctctt gcaattgcta aaagccttaa taggaatatc ataaataaga
    23581 ttatcaacac tgccattcct attacaccaa gttcttcacc tacaacagca aatataaaat
    23641 cactatcttg tacaggtaaa aaatcttctt gattttgact tccattgtaa agtcctttac
    23701 cagttacgcc cccagaacca attgcaatca gagattgcat aacttgatag tttcctttta
    23761 gagttacatc ttctggattt agaaaagctt ctattcttac cttttgatgg tctgccatca
    23821 ttaaatacat cagtggcatt gacactaata gtatgattat tcctcttttt atcaactttg
    23881 agctaagacc tgctgtgaac agcattgcaa atatcataca acaaaataca attcctgttc
    23941 ccaagtctgg ttgtgcaatc aataatccga taaatggaag agaataaact acaacaggca
    24001 taacttcctt taacgtattt aatttatcct ttttggattc aagtatcttt gcataactta
    24061 gtacaaatgt taatttgact atttcagatg tctgcaagtc aagtggtcct aagttaatcc
    24121 acgacctagc tccacctttt actgtcccaa ttccaggtaa taaaactatg gctaacaaaa
    24181 taagacttat tatataaagc gctttataat acctgcctag aagattatag tcaaaaaata
    24241 atatgactat aatcattcct ataccaagta caaaagctaa tccttgttta atcaattgat
    24301 tatatgaacc tgttgaatta gcatgtgttg cactactaag tataacaagc ccaaaaataa
    24361 agatagctaa tactgtaact ataagtttcc agtctaactg ttttatcaac ttaattgtcg
    24421 acttataatt aatattgatt tttttcaaag aatcaccgtc tttctatctt taaacatata
    24481 attaaataaa aggggcatat accaataagg atatccccct tttaagcact aattacatac
    24541 atctatcttt tatattcttt agtggtatat tagcaactaa tgcagataca ggtttgtcat
    24601 catgctcacc tctgcattta gacattttta tttcaagacc atcatcttct atttctgcat
    24661 aattagctat tacttttaaa atgtctgttt ttatcatctc taaaagttgt ggtgaacaat
    24721 ctactctatc atgaactaaa actagcttta acctctcttt agcaacagat ttactagttt
    24781 tagcctcgtt agaaaaaact ctaaataaat ctaacacaga tgtatcctcc tttgctactt
    24841 agccatgcta aacatttttt taagtctacc aaagaatcca tcttcaactt caagatcaag
    24901 tagaggaact tcttcattta gtatcctttt tgcgatattt ttgtatgctt gaccagcaag
    24961 tgacttagaa tcaagtatag ctggctctcc tttatttgtt gatataatta tgctttcatc
    25021 atcaggaaca agacctaaca aatctattgc taatatttct attatatctt gtttatccat
    25081 catgtctcca cgcttaacca tatcatttct aattctattt ataactaatc ttatctcttt
    25141 tatttcattt gcttctaata gacctattat tctatcagca tctcttactg ctgatatttc
    25201 tggattagta actacaatag ctctatctgc cccagctact gcatttttaa agccttgctc
    25261 aatacctgct ggacagtcta ttattatata ctcgaaagat tcttttagtt tctcacacag
    25321 atcaatcatc tgctcaactg agacagcatt tttatctcta gtttgtgctg ctggtaataa
    25381 atatagatta tcaaatcttt tgtcttttat tagagcttgc ttaagcctac aagttccttc
    25441 aactacatct actatgtcat aaactattcg attttcaaga cccattacta catctaagtt
    25501 tctaagtcca atatctgcat ccacaactac tgttttttta ttttctaggc ttagcgcagt
    25561 tcctaagttt gctgcggtag tagtttttcc aaccccacct ttaccagatg ttataactat
    25621 aacttcgctc ataatactac cccctatttt tctttctatt tgtctaactt tgacaaatag
    25681 ctttcgatta caattcttcc attacttaca aaggctattt ctgggctaat ttctgattca
    25741 ttttcataat tttcttcatc atctggagct tctgcaatat tatctgctat ttgtaatatt
    25801 ttaggattaa gatttccagc aacaacatat gcaaattcat tgccttctgc acctgcatgt
    25861 acaaaacctt ctattttacc cattacaaaa acattacctc ctgctacaac cttagcacca
    25921 gcatttatat ctcccataac aactgtattt gattttgaaa ggacttttga accaggtttc
    25981 atatcattca atataactac atcaccttca aattcaatat tttcaccaga tcttagggta
    26041 ttgacatatt ttgttggaaa attactattt tcttcaattt tttgatcttc aacaaattcc
    26101 acatcaaatc tagaagtaat tccttcttta agttctagaa tctccatgtc agttaaacaa
    26161 tcactattaa ttttactaat tttagcccca ttaaaaaagc caacatatgc ttccaatttg
    26221 tttattattt tttcctgtat ttcctcaaat ggagcttctc tttttatatt tactattatc
    26281 cctcttttat tacccttgaa ctctactagt tcttgactac aaatttctct taaagacata
    26341 acaacctcca gagtgatata tcatttatat tcttcaaata cgctttaaac ccttttattt
    26401 tttctatata aagctaaagt ttatacatag attaagctat ctattaattt gtgactcgaa
    26461 atttatattt tcgtcagaag aattgttaac atcattcgtc ttgttgtcat ttttactatt
    26521 agttggctct aatcccatat aagttccaat aacttctcta gttggtaaaa gtgagaatac
    26581 acttgaatca ccttgaggaa ttacacatac aacagctatt tctgggtcat ctgctggagc
    26641 aaaagcaaca gtccatgtaa aagaaccata atcttgttta aatctatcta tttggtcatc
    26701 tgttattttt ggatttaatt cttttatagc ttttcttaga tatgaagaat tcaccttatc
    26761 agtgtcctct aatctaactt ttactccatc ttctaattct tcctctaatt tctttctttc
    26821 ttcgtctttc aaatctttat tttctaattt cttttttatt tccttttcct tagctaatga
    26881 aagctctttt tctttttctg ctttcatctt atcagctagt ttaatcgcat catttaggtt
    26941 gacattataa gatgacatat gactttttaa atattcatac tcgttatctg taggtatttt
    27001 cccacttttc tcagctgtac cagtttttgc tgctacatct attggaaaat cagcaaaagc
    27061 actcttcgct gtaccttgtc ttgcaaccaa tttcatacct tttgttaatt cttttaagtt
    27121 atctggattt ttaaaaggta ttttttcgac tttcttctgg tcattaattt taactgatga
    27181 ataatcactt gaaacagctc tatcaactac agataattct actaaattac ctccatttgc
    27241 tatagcagct acatatcttg atatttgagc tggtgtataa gcattttcac cttgacctat
    27301 agctaagtta aatgtatctg cagtactcca ttttgcaaag ttaaaataac tgaatactgc
    27361 taaatctgct acttcttcta ttctatcttc tttaacattc attttcttta gcctattcat
    27421 tgtttcgact ctaccaggag ttttcttttc tgctgcccag cttacaatct cattgattct
    27481 tttctcatat tctttaggat ttttttctct agttatatca acaaaatcat ttgccatttc
    27541 tctttctaaa tttgacttta gaagagcttg tgttgatttc aatttatctt ctgtgctagg
    27601 aactttacct gctctttctt ctacttcatc ttgaagccct gtattttggt caagcccaaa
    27661 taattttgca tactcaagta ttttatttgc attcatatct ataccaatgc tttttccatc
    27721 tggccatgtt ttacctgtac caattgttgc catatatata ttacaagact cttgtatcgc
    27781 tttatataag tttgtcatac catggtttcc tctaccatgg ttccatacat agtcaccaaa
    27841 agatttttta cctaacatta taaccccagg gtcatttata gtaaagtttg gatccaaacc
    27901 attttctaat gctgccattg aagttagcat cttaaatgaa gaacctggct gaaattcccc
    27961 ttgtgtaacc aagtttaaaa gtggacttcc tgctagtaag tcatttggat tttttggttg
    28021 aagtgcttta taatcctctg tagaaatacc ttttgcaaat ttatttgggt cataattagg
    28081 ataacttgat gaagctaata cttctccatt tttaacatca atagctataa gagctgctga
    28141 ctgtgctttt cctgcatatg cactaattgg tttgtcccca aatttacttt taaaagtacc
    28201 tcctttagaa gcaacttcga ttatctgttt taatgcatta tctgaaactt cttgtaaatc
    28261 tttatctagt gtaagataca cagtatctcc tgatttaggt tttttagatt caatttcttt
    28321 actgattcta cccaatgcat caactttaac cattttataa ccatcagttc ctcttaatct
    28381 actttcatta ctcttttcta ctcctgcaag acctaccata tctccagttt cataaccttt
    28441 ttgaaggtat gattctattt gagtggatgg catttttcct acatatccta acatatgaga
    28501 agctaatgac ccattaggat aatatcttac tggttctact gctattgaaa caccaacaag
    28561 gtccatagca ctttcttcaa tttgagcaat cgtagtttct cctacatcct tagcaatagt
    28621 tactggatta tattgagaat atccttttga ttttatcaaa tcccttacga ccattatttt
    28681 tcttgcatct tcatcactca aacttttatc aatttctaat gcatcactat ttcttacttt
    28741 ttcaaacgct tctttggcac tcagtttagt ttcttttatc ttataactag ccaaccaatc
    28801 tctcttatct ctttctgctg tgaacatcca tttactaact aaaataggtg gataatatcc
    28861 attttcattt agttttgcct gtaatcttgt cgcatccaat cttttatctt cttgagataa
    28921 tattccagct gatataagtt tgtctactaa gtaataaaaa ctttccttag cattataatc
    28981 atttggaata ccattttctg atttatattc cctaatatct ctgtcatatg tataatagta
    29041 ctttccattt tctacatata taggaaactc atctacatat tcttcaccat ttctctccag
    29101 caaatttata agttttaatg atatttcatt tgctcttgaa tgcttatttg catctttctt
    29161 attaatatcg ttacctgaaa cttgaacagt aaataagttt ttatttcctg ccaacagtct
    29221 tccatatcta tcttttattt ctcctcttgg agcttctatt gccaactttt tatatgtttt
    29281 attctcagct aactcattgt aatattcata tttaaatgta gtcatataga ttatttttac
    29341 taaaatagct aaaaatatca cgctcatgac tatcttaatt atttttagtc tatcaacttg
    29401 tttattttct tccatgaaat caccaactaa tcttctttaa gttttaaaac tgctctttta
    29461 gataagcgat atattactaa accaattaaa ctattcacta ttggtgctac tagtagacct
    29521 tttacaaaaa gtgttgatat gttgtagctt tgataaatta tactagatgt acctatattg
    29581 acaattgaat caattaaact gcctataaaa attaaaacga aagtaataat ataactacct
    29641 ttatatagct gatctctcat gtatccaatt gcatatgcaa taataaacaa aattaatgca
    29701 tttacaccaa aaattccacc aacggttatg tctttaataa gccctattat tgctgctata
    29761 atcccacctt ctaattcatc taaataaaga gagattatgg ttacatatat aagaactaaa
    29821 ttaaagctta tgccaaaaat atctatataa tttgttatac tattttctat agtcataagc
    29881 acaatcccca acagacaaag taaaactttt ttcattgttt ttatcccctt tatcctatat
    29941 ttcttggttc tatgactaca acgtcattta tattcttaaa atcaacataa ggttttacaa
    30001 ctacatattt taatgactta tctttatcat caaccacctt ttcaacttcg ccaattggta
    30061 taccatctgg gaagaatcca agacctgatg ttgttattat atctccttga attacattat
    30121 atgatgagtc aaacatatat ccttgcaaat atcctttact attataacta tctttattat
    30181 ctaaagtagt attttgagta attgtacctt tagcattggc atcctttgct agtttaaagc
    30241 ttacagatgc cttagaatcc aatagtgaaa ttgccttact ataattgttg gaaacttcat
    30301 aaactatgcc aactaaccca ctaccattca taactatact ttcttttttt acacctgaat
    30361 tttttcctgc acctatgaca aaactctcat accagtttcc atcattttta ccaacaacac
    30421 ttgctgaaat acttgtcgcc ttatactctt cttgtacaaa gttcagtgtc ttttttaact
    30481 cttctagcga ttctgtttta tctagtttgg catttaaagc tatcatatct tttttaagtt
    30541 tttcattttc ttcttccaat ttttttacct ttttagaatt atctttaaaa tttgctacat
    30601 ctttaaaacc atttttgata aaagaaaatc catcatttat tcccttacct acacttgtaa
    30661 tagcatctga agctactcct aaatttactg gactaccact agaaaattta ccaattgata
    30721 tacccacaat tccaattaaa gtgatagcaa ctacgcccgt tgctatcact ttaacattaa
    30781 tccttttttt ctcatttttg ttcttgtcaa atctcaaggc catcaccaac ttctaattct
    30841 tagtattcat cattaatact ttttcaaaga tttcttggtc ttcaacagat ttacctgttc
    30901 caagtgcaac acaatcaaga ggtgtttctg ctatttgtac agacatacca gtttcctgtg
    30961 taataagctt atcaagacct ctaagcaaag cgcctcctcc tgttagcatt attccgtttt
    31021 ccattatatc tgaggctaat tctggtggag ttctttctag tgtagatttt attgcatcta
    31081 ctattgaact tacaggttct tttaatgctt ctctaacttc tgtagagcat atttctattg
    31141 ttttaggtaa tcctgagatt aaatctctac ctcttatttg catatttatt tcttcatcat
    31201 ctttaaatgt agaacctatg ttaattttta cattttcagc agttctttca cctatcataa
    31261 gattatattc tttttttaca taagccacta tagactcgtc aaattcgtct ccacctattc
    31321 ttatagattt agcagtaacg attcctccta aggatattac agctatttct gaagtacctc
    31381 caccaatatc aactaccata ttaccttctg gttcttcaac ttttaatcca gcccctatag
    31441 ccgctgccat tggctcttct ataaggaatg catctttagc tccagcttgt cttgcagcct
    31501 cttctatagc tctcttttct acttctgtaa ctccaaaagg aacacatata gctattcttg
    31561 gacttacaac acctttttta tcagccgctt tttgtataaa atagctaatc attgattgag
    31621 ttatgtcaaa atcagctatt actccatctt tcataggtct tatagctact atatttcctg
    31681 gtgttctacc tatcattttt ttggcttctt cacctactgc taatacctct ttactatcat
    31741 ctcttattgc gacaactgat ggttctctaa caacaatacc ttgtcctttt atgtaaacta
    31801 atgtatttgc agtccctaaa tctattccca tatcctttgt catcttatta aaactaaaaa
    31861 aacctttttt ttctttcttt ttttccttag ccatgatttt actccttcct actattaaga
    31921 atcatgttta aaacattctc ctattatttt atcacatata aagtcaaatt atcatatttt
    31981 ctttaaagct aaagtataat ccatctccaa taattatatg gtctattatt tctattccaa
    32041 ttatttctcc acatttaata agtcttgatg tgatattttt atcttctctt gatggttcta
    32101 cacttcctga ggggtgatta tgcatcacta ttatcttact tgcacttctt cttatagctt
    32161 ctttaaaaac ctctcttgga tggactaatg acgagcttaa agtccctata gatacatcta
    32221 catcagatat tatctcattt tttgtgttta aaagaactgc tttaaaaacc tcttttttta
    32281 aataccttag gctatccata taatacctct gtatatccca aggattcctt attttatact
    32341 ttataggttt aaaactagct actctagagc ctagttctaa agctgcttta atttgggttg
    32401 attttgataa cccaattcca tctatattac acagctcctc tattgtcata tcttctaaat
    32461 gtctaatacc ctgaatatct ctatttatta tatagttggc taattcaata gcatttttat
    32521 tcttgttgcc agttcttaaa agtatagcca acaactcagc atttgataag ctttttacgc
    32581 ctttggcaag catcttttct ctgggtcttt cctctggtgc catttctttt accttaatgg
    32641 ttgaattaaa tgactttttc agataaatca cactccataa aaaagattta tactaaaata
    32701 tttttttaat aggtcgccta accttgaaat tggaagacca actatattaa aataatctcc
    32761 tctaatttct tcaactaaca aagctccata accctgtata ccataggctc ctgctttgtc
    32821 aaatgactca ttagttttca gataatcctc aatatcctgc tctgataacg ttttaaattt
    32881 cacattgctg attacatagt caattacctt tttatcttcg cacaagttta ttaagctaat
    32941 acctgttatg acttgatgct ctcttccaga tagtcttttt aacatatctc ttgcacaaga
    33001 ctcatctttt ggttttccta aaatagcatt gtctaaaaca acaactgtat cagctccaat
    33061 aacaacatct tcattatgtt cagatgctac agacatactt ttttcaaaag ctaatctcat
    33121 aactaaatgt tttggtgttt caccttccaa tataatctca tcaatttcat ttttaattat
    33181 atcaaatctt acattcgtat tctctagaat ttctttcctt cttggagagg ctgatgccaa
    33241 gattatattc atttattcac ctcatttgta cgtaatttgt acctatttag tctatcacta
    33301 tattgtaaaa aattcaacag aaatgtcgaa ccttttttgt tacactattg ttatatttat
    33361 taccattaga ataaatatac ataaaataga ggtatggaaa ttattccata cctctgtttt
    33421 atgtactcat tagagatatg gaaattattc catatcctta ttttgtccat attacaaaat
    33481 tttaatagct ttctttggac atttttccat acataaatgg catcctacac atttatctgc
    33541 atctacctta tgtttttctt ttaattctcc ctctattgca tcaaacttac attgtttttt
    33601 gcacactgta catccaacac aaagttcttg gtcaatagta actttctttt tcttagttat
    33661 gtcacctgat attacttttg tagggcattt tgctacacat tgcatacacc ctacacactt
    33721 attagggtct atcttagcta ttttgtcttc aaatattatt gcatcaaatt tacaagcttt
    33781 tacacacatt ccacagccaa tacatccagc agtacatttt tccttaacag ctttaccaaa
    33841 ctctttgcta ttacactcta caactacttc ttgactttct ggttttgtga ttattatacc
    33901 cttaggacaa acttctttac attttccaca atttacacac ttttcttcat ctattactgc
    33961 tattccatca actatagaaa tagcatcaaa tttacaagca tccttacatg ttccaagacc
    34021 taaacatcca aatttacaca tcttagcacc tgagtttaaa acatttgctg ctctacaatc
    34081 tgatattcct tcatactcat atttatcttt tgcacttgaa caagttcctt tacaaataac
    34141 ttttgctact tgtttctcac ctgcttcagc acttattccc attatttctc caacttttgc
    34201 accaacatct gctccaccta cagggcaacc attaactggt gcattgcctt caactatcgc
    34261 atttgcaaga cctccacaac ctggaaatcc acaacctcca cagttggctc ctggaagtac
    34321 tcctagtata gcttccactc tctcgtctac ttctacagca aactttttag atgcgaaatc
    34381 tagtactatc ccgaagatta agcccataat tcctaaaact aatacagctg taagtatcac
    34441 cattttcacc cctctttttt atagctttat aagtcctgta aatcctaaga aagctattga
    34501 cattaaacct gctgatataa gcgttatagg gaaaccttta aatgcttctg gtatatcagc
    34561 taactctagt ctttctctta tacctgcgaa tattactatt gctaaagtaa atccagctcc
    34621 ggctccaaat ccatttatta ttgtttctac taaattataa cttttttgaa cattaactag
    34681 agctatacca agaactgcac agtttgtagt tataagaggt aaataaactc ctaatgcttg
    34741 atataaagat ggactcatct tttgaattac catttcaacg aactgaacta tagaagctat
    34801 aaccaatata aaagctattg tttgtaagaa tccagttcca gtttttacta ataaaatctg
    34861 tataaaataa gttataattg aagctagagt taaaacgaac gtaaccgcaa ctcccatccc
    34921 tactgctgta tcaaccttct tagaaactcc caagaaagga catataccca agaattgaga
    34981 tgttataacg ttattaacaa gaacgatact taaaaataaa agtattaaat tcatttatta
    35041 cacctccact atgctttttt acttcttaat ttattaaatc ctgcaaataa gaatcctaat
    35101 gttaagaatg cacctggtgg taatataaat attaatactg gttggaaaga tgctccaaat
    35161 aatgtcattc caaataaact accatttcca agtaattctc ttactgcacc tattattgta
    35221 agtgcaacag taaatccaag accttgacct acaccatcaa ctattgaagg catagctcct
    35281 gttttgaaag caaaactttc tgcacgagct aatattaaac agttaacaac tattaatggt
    35341 atatatatac caagagcctt atcaagagca ggaacatatg cttttaaaag catacctact
    35401 attgtaacaa atgtagctat aactactata aatataggta ttcttatctt atctggtgta
    35461 atttttctta ttaaagatat aactaaattt gcacatatta aaactgctgc tgttgaaaga
    35521 cccataccaa ttccatttat tgctgaagtt gtaacggcta gtgttggaca catacctata
    35581 acttgaacaa atgttgggtt ctcatctatt agcccatttt taaatacttt agctaaattc
    35641 ataattaacc ctccttattt attaagagca ctattgaaaa catctatagc agcatttact
    35701 cctgtagtaa ctgctgtaga tgtaatagtt gcacctgata ttgctaatat ttgattatct
    35761 gctgttgtac ttccttttgc tacttcaaga ggctcagcag tttttccttt gtattgaccc
    35821 ttaaatgcat catccttagc ttttgctcca agacctgctg tttctgacat attaccaatg
    35881 tcaacacctg taacttgacc ttcagatgat atacctacca taacttcaat ttctccacca
    35941 tatccacttg gtttagcttt taaagtatat ccaaccactt cagaaccatc taaaccttca
    36001 tacacttcag ctataagacc atctccaagg tctttatatg tacttttatc catttcttta
    36061 aattcttttg cttctggaag gactgctttt ctaagttcat tattttcttg tatatttctt
    36121 tgttctatta ctggagctgt aacctgatta gtagctccaa gagctaatgc agctattgca
    36181 cttatagcaa gtaaagtacc acctaatctc accatactgt tcattattta gccacctccc
    36241 caaatactct atttctaaca aacttatcta taagtggagc aagacagttc actaatagta
    36301 ttgagtaaga tacaccttct ggatatccac catacattct tataacagtt gttataagac
    36361 cagctaatac agcgtatatt atttgacctt ttttagtcat aggcgaagtt gtataatccg
    36421 taagcatgaa gaatccacct aacataagtc ctccagcaaa cagttgatat attgcgaaag
    36481 ttatattaaa tccacctaaa aggaatgtta atataaatac agttgctatg taaaatactg
    36541 gtataacata atttattatg cctttataca ttaggtatac tccacctaat aataataata
    36601 ttgctgatgt ctcacctata catccaccaa tattccctat catcatgtca gcaagactaa
    36661 ttccattgct agaaaggtct gccagtcctg ctgctccatt tttcaaaaag cttaatggag
    36721 ttgctgtagt aactgcatct aaatttttac ctatccagtt aacacctggt tgagtccaag
    36781 cagtcattgc tactgggaat gatgctaata aaaatgctct tgcagcaagt gctggattga
    36841 caaagttaca tccaattcca ccaaatacca ttttaactac taatattgca aatattcctc
    36901 ctactagaca catccaccaa ggaagtgatg ctggtacgtt aaatgctaat aataatcctg
    36961 ttacaacagc tgaaaaatct cctatagtac ttttttgctt cgtaaatttt tgatataaaa
    37021 attcagtacc tactgtacca agtatacaaa aaaacatagc actcaaagca ttaagtctaa
    37081 agaagtatac tcctgctact gctgctggaa ggagtgctat aataacttgt ttcattatat
    37141 atgaagtatc ttcattactt ctcacatgag gagaagatga tactatcaac ttattttcca
    37201 tcgtttttcc cccttaactt tctttatttc tgagcagctt gctttcttct ctttgctcct
    37261 atttctctct ttgctgatct tatagattga agtaatggtc ttcttgctgg acaaataaat
    37321 gaacaagacc cacattctat acaatccatt gctctatgat attcagctgt gtcatagtca
    37381 tcttttaaag aatatgcact tatgaaaagt ggttgtaaga atgatggaca tacatctgta
    37441 catcttccac atcttaaaca gttttgaata tctggagtac gtgattcttc ctcatccaag
    37501 cataaaattc ctgaagaacc tttgttagtc gctatttcag tagtatattg agctattccc
    37561 atcataggtc cacccattat aaccttacca atcttcttat cttctttaaa tccaccacat
    37621 tgttctatta tttctgaaac taatgttcca acttttgtta ttaggttctt tggctctttg
    37681 atgcaactac ctgttattgt agtgattctt tcaaccaaag gcatacctgt tttaatagac
    37741 ttagctattt gtgctgctgt ggcaacattg tcaacaactg cacctgctgc tattggtaat
    37801 ccaccagatg gaacttcttt gcctgtacac gcataaataa gttgtttctc tgctccttgt
    37861 ggatatttca cttgaaggcc aacaacttcg atttcactat agtctttagc tacattttga
    37921 attgcttcta tagcatctgg tttattcgtt tcaattccta taaatccttt tttgacatct
    37981 aataccttca ttaatgctct taaaccaaac acaacatctt ctggattttc aaccattaat
    38041 ctgtggtctg cagttaagta tggttcacat tctgcaccat ttaatataac tacttctgcc
    38101 ttgctatctg gtggaggaga tacttttaca tggttaggga atgtagctcc acccatacct
    38161 actattcctg cctcttttat gatacctact atatcttctt tgctcaaatc ctctaactga
    38221 ccttttggtt gaacactctc atgtaattct tccttaaagt cattttcgat aactacacat
    38281 tgagctgaac ctcctggtac ttcatgttgt tcaatagcaa taactttacc tgatactgaa
    38341 gaatgaacgt tacatgaaac aaaaccttgt tgttcaccta ttttttgccc aaactttact
    38401 tcatcaccaa cttcaacaat aggtttagct ggtgccccta tatgttgctg aagaggaatg
    38461 taaactatct ttggagcttg agctttttca agtgcctttg tgttagagta ctcttttcta
    38521 tatggaggat gtatccctcc cttaaaagtt aagagtttca ttgttttacc cccttatcta
    38581 taaaaaaaca ttttttctgc cttctataag tatactatat atattaaaaa atcttaacaa
    38641 ttgttaaaaa aatatccgta tttttataat ttattttata aatcaatacc tctatattaa
    38701 gtcaaactga ggaaaaggat tgcttaatta aacaatcctt ttcatatagc tttctaaagt
    38761 ccaaattttc tgtattttat tttatagaat ttataaacat agagtactcc tgcatggatg
    38821 ataaaagcag acttttactt acactatatt tttcttcatt tgctgctttt gaagctgtat
    38881 caattttttc attcacattc tttacatact ctattaaatt atctttaaat aaacgcattt
    38941 cagaatagtc aatcttttca gcttcttttg atatattttg tgatattgcc tttctatttg
    39001 tcaaaatagt attatatttt tccatatcta cattattttc agcattcgac caaaaacttg
    39061 attcttcttt aaagtttgtt attaatttat ttaattcttt agatatactc tctatataag
    39121 cgtagttact tgtatactct aaagacaaca taggtgcatc taagtgtgat aaaaatgcat
    39181 ctggaaacac ctttcttaca ctgcttatct gctttctaac atcattttca tcaaaagagg
    39241 aataggtctg tatttttttt actccatcct tctccataac tgaaaaaggt atgtcattat
    39301 taactaatga tgtctgtatt tttttcaaat catcattatt atctattgca gcaacttgaa
    39361 tagtgtacat atcccagcct tctatagtag ctaatttgac ttcttctggc tctttagtgt
    39421 tatttaccgc tttttctgga ttagtttctt gtttatcatc tgaattggtt tgtgatttag
    39481 attttttccc tttttttatt gaatttaatt catcagatat atctttataa gttatatctg
    39541 atgaattatt tagaaatggt attttagccg atacatactc caatatcttg ctatctttta
    39601 tttttgtata agaataatag ccaattagac acaagcaagc aatcgttata acatatttac
    39661 gtaaatcaat cttatgtcta ttattattaa atcctctgta tatcgttttt cttctattca
    39721 ttagtttgtc cctcccaaaa ttatattatt aataaagtat atttttaaga gtcacaattt
    39781 atgaatataa ataattattt cttctaattt tttaataaga aattgtactt actaaacaaa
    39841 tcttcttgca ccaagtaata ctttagacca atatgaacta gttaaattat ccactttaac
    39901 cttattagga ttagtctgag taccactaca atggataaat ttactatttc ctacatatat
    39961 acctacatga ttagttgttc catcaccatc agtgtcaaaa taaactaaat ctcctggtgc
    40021 ataattcccc atagaaattg cacttccaaa attagcctgt tctctagaaa ctctaggaat
    40081 agaaacgcct acagaatgtt taaaaacata ctgtgtaaat ccagaacagt caaatttatc
    40141 aggtcctgaa gctccccatt gatatggtat tccaataaga gtatatgcaa aatctacgat
    40201 tgttgaacct tttgctgtag atttatctga atttccagta aatgatggct ttgagttact
    40261 attagattga gaattttggt tagatgatga atttggtttt tcttttgtac cttcattagt
    40321 ctcagaaata taactggcac tcacccatcc aattgttcca ctcgataact ttaccttata
    40381 ccaaccatta tttttggatt ttaattcaac aacatctcca ccatttaatt ttcctattat
    40441 agaatagctt gtcccaggac cacttcttac atttaaactc acagcagatg ttaccttacc
    40501 attcttgcct tcaattgatt cttcgctaga tggtttttta tcagaattat tagtactatt
    40561 tgaattacta gaattattcg ttccaacatc ctctgatgtt ttagagatat attggctact
    40621 agcccatcca gtaactccat ttgatagttt tattttatac catccattgc tttgttctag
    40681 taactttact acatctccat tatttgcttt accaactaat gaatagttag tacctgcacc
    40741 acttcttaca ttcagtctag aactcacatt tactttacca tttccactaa tagttgtccc
    40801 acttgaagtt ggattatttt gatttgatgt accttcagat gaaccacttg ttgatatgta
    40861 ttttgcgctt ccccatccaa caacagaact cgataccctt actttatacc atccattaga
    40921 cttttctaaa atctctacag tttttccctt gtataatttt gctaccttat cacaatcaga
    40981 acttggtcca cttcttatat tcaaggcact tgctgttact gttccctttt caagagcact
    41041 tgcatttatg gagctaacag atactgctac tgccccaatt cctaaagctg ctatagcttt
    41101 cttcactact atcactcccc ccaacaaatt tttatagtca taaattcata acattattat
    41161 ccatttttag tccctacaat ttaatgataa cttattctct tattaattgt aaagaaatta
    41221 taaacatatc cttaaaatta atgattttta ggaagtattt caatccaata attatctggg
    41281 tccgctataa aataaattcc catactttca ttttcaaaac atatgcaatc taaatcttta
    41341 tgaagttttt ttgcctcatc aaactcctca acttctaaag ccagatgaaa ttcattgtct
    41401 cctaaattat atggtctgtc ccaatctcta agccaagtta attctaatgt atgactagta
    41461 ataccatctc ctaaataaac taatataaaa cttccatctt ctgcttcctt acgctttacc
    41521 tctttaagcc ctaaagcttt tttataaaaa tctaaacttt tttctaagtt agtaacattg
    41581 aaattgttat ggcaaaaatt aaacttcatt ttgaaatcac tctccaattt ttattttttt
    41641 tatattatat cattattata aatttattta aatcatatta agttaaaaat ttgaatgatg
    41701 atgaccaatt accaaatggt ggtaaattat ttaaaagaat atgtcaaaaa aagaataagc
    41761 tctttcaaat gcacaaaaaa tttataccca agttatactt aatcatgcaa attggcagaa
    41821 cttattcttt aaaactctaa cttttaagtt tttctttgat aatataattt attacttttt
    41881 ttctaatatc ttcagcatta taatcatctt ctacttctat atccaaaagt tttgctattg
    41941 acctcatatc ttctctagtc tttgacctat agcttgatat taattcatct tttattttct
    42001 ctggttctaa aagatattct tcatctcctc ttttgaaaac aacgtatttt tgagcatatg
    42061 aacttctatt atagtatata tatcttgata tttttcttaa aatttgatta tatgaaagtc
    42121 gcttgttaat atcaagtttt aagtactctg aaaaagcaaa tagctctttt tttgatttaa
    42181 ataatgcttc tttctttata gtccttgata ttgaagttac actttcttga tatgcacact
    42241 tttttaacat ttttaaatat actctattaa gaccaatact ttgattgaat ttttttatat
    42301 tattattaat aatcttatcc aagttacctt caaagtattt ttttgctcct ttttgtgata
    42361 cataactctc aagttctttg tgggccatat caagtatcat tttttttaaa tcctctttat
    42421 atcccctaga ttccatgata ctccctccct tagctattta tagtatattc aaaaagctca
    42481 agaaatgtga gtcattacaa aattttttta ctttttatgt atatattaat ttaaaagggg
    42541 agataatagt aatgtaaaat caaacatact caatctcccc catttttaga cctctattac
    42601 tcccccaata gaggcctttt tttagtttat caatttctat tcaattccct ttagttcaaa
    42661 tcctaattct gctatcactt cttttaattt ttcaatagat atatcatctt tcatatctac
    42721 agatgcacac ttattttcta aatccacatc taaaacttca ataccatcta tatcttctgt
    42781 taatgcagtt ttaagatggt ttacacaatg accacaactc ataccttcta ctaatagttt
    42841 cttcttcatt taattacctc cttatacccc ataagggtat tctatcatat agtttatact
    42901 ttttaaatag aaattaatca tttaatttga ttcattcgat tttatatcta aattagatat
    42961 tccctcatat acatcaaaat catttggagt aattttacct tttaatctac tattacttac
    43021 aatatagttg tttctcacag ctaaacttat aaatgttgca ttatctttta tatatgtctg
    43081 tacatctttg tatgcttttt ttgtttcaat ttcagacgta gaacttgtaa gtgcagacat
    43141 atatccattt agcttatcat cagtatatcc actacttgct ataatactac ttgcatctgg
    43201 tataattgat agtttccatc caactaatgc taaatcataa tttttagaat taagagcatt
    43261 ttccatatcc ttatctgaca gctgatttac tgtactattt attcctatag cttttaagtt
    43321 ttcatttatt atgtttgcag tttttattct ctcactatta tctctgttta ctattatctt
    43381 taagttcatt tcagaaagac ttttctttac ttcctctttt tctctatttt ttttcttttc
    43441 agcttctttt ttgattctat cttcttctgc ttttttagct tttgcttctt cttctggcgt
    43501 aagcttcttt gagttctttt tagctgattt tttctgattt tttactttat tgtcattttg
    43561 atttactgag tttatatttg catattctac cttagcaaga cactctatcg ccttatcttt
    43621 attaaactct aaatccttca tttcactatt atagtatttt gattttgaat taagtggaaa
    43681 attaactgga gtagcatcat ccatataacc ttcactaata attctatctt tatctataga
    43741 gtgagcaatt gcttttctaa aattaacatc tttaaaaaat ggattattat aattaaataa
    43801 tacacactca taatctcttc cttgatattt tgttatatta aactcttttt cttgaaactt
    43861 gcttaaatca tttaatgtaa cattggttat atcactatca agagccataa ccatagatgt
    43921 ccttgcctct tcattaggca ccatacctac ttttatgttc ttcatggtct ttggaacttc
    43981 ttcatagtaa tctttgttta cagataaaac cattccttct ctttctgtat atgattctat
    44041 tttatatttc ccatttccta tcatattatt attcttgtca tttacatcct ttgaatctaa
    44101 atgattttga gatacgattg gaaaaattaa actatcaatt gaaaaagcat atctagcttt
    44161 aaattttatt gtaaaatctt tatctgattt aatattcaca gaagctatat ttttagtaaa
    44221 ttcattatat ggactatctg cacttttttg aattaaacca atagtatagt ttacatcatt
    44281 tgaagtaaca ttttttccat catgccactt tgcatctttt agctttatat ctatactcat
    44341 tccatcctga gctatattat actccttaac taattgagga attacattgt agttctcatc
    44401 tatagtaaat aaactatcat aaactaaatt cattatataa ccaacagact tatcagtatt
    44461 agttatagga tttatagttt ttggagttac cattgttaag tttatatact tagcatctat
    44521 agaactttga ctttgtaaac ttgaatcact actactttgt tttgttttag tattactaca
    44581 accagctacc ataagagtta tagctaaaac gactgttaag acttttattc tcttcattag
    44641 ttttttcctt tcttgccata tatcttatta taatgttcgt aattattttt tactttttct
    44701 acatattttg aagtttgctt aaaaggtata tcatgtagat tttcgccatc tttactatat
    44761 tcattatttt ctaaccattt tttcacatta cctgaaccac cattatatgc agctatcact
    44821 aaatctaatt taccaaattc tttgtataac ttacttaaat accaacagcc aagtcttata
    44881 ttagtctctg ggtcgaaaat atccacattt tttaaattta gttcctctgc tccccaatct
    44941 ctagttatat ctaatatttg cattaatcct tttgcttcct tttttgaaac agcagaacta
    45001 ttaaacttac tttcggcttt aataacactg taaactatat tttcatctaa attaaattct
    45061 tttgaatact tttctacata ctctgaatat tttttaggat ataaaaattt atgtattact
    45121 ttgctttcca ttaatagtgc cccaaataag attataaaaa tagatagaat caatactttc
    45181 ttactattca cgccaattct ccttcatgta ctcaataaat ttatgtgctt tactttctaa
    45241 ttcagttatt gttcccgaat tatctattat ataatcacca tatttggatt tttcttcctg
    45301 actcatctgt gaatttatcc tactaagtgc ttcctgctta ctacaattat ctctcttttg
    45361 tattctacta atttgtactt cttgtttgca agtaactact aatagcttgt caaccatatc
    45421 taaaaaacca ctttctacca atattgctgc atctaatact actatatttt cgcctttttt
    45481 tctcaattct tctatttcac ttattatttt ttctcttatt cgcggatgag tcaagctatt
    45541 taattcctta agtttttctt catcgctaaa aactattttc ccaagagctt ttctatttag
    45601 agttccatca tcatttttta tactttgccc aaaatggaca aatacttttt ccaataacaa
    45661 cttatcctca aatatcttcc tggatataat atcagcatcc actatagaaa tattaagatt
    45721 tctaaatata tttgataggc tgctttttcc acagcctatt cctcctgtaa gtcctaatat
    45781 caacataaaa tcacctactt tgtctcatac caagaactac ctacatttaa atctacatct
    45841 aagtgaacat ccatatttac agcattttcc atttcttctt ttactatttt cttaactata
    45901 tctatttcat catcaattgc ttcaactatc aactcgtcgt gaacttgtag tataagtttt
    45961 gatttcaaat tgttctcttc caatttttta tgaacattta tcatagcaat ttttattata
    46021 tctgctgcac ttccttgtat tggtgcattc attgcaaatc tctttcctct atttctttcc
    46081 ataaaattgc ttgactttat ttctggtata tatcttcttc tgtttaaaat tgttacagca
    46141 tatccatcct cactagcctt ttctactgtt gtgtccataa actcttttat tttatggtat
    46201 ttagcaaaat aactttcgat atattctttc gcctttggaa caggtatatt taaatcatca
    46261 gctagaccaa agtcactttt accatatata ataccaaagt ttacagcttt agctgcacct
    46321 ctcaattcac tagtaacatc ttccatagga acattaaaaa cttgtgaagc tgttttggta
    46381 tgaatatctt catgatgttt aaatgcttct atcatatttt catcctgact catatgtgca
    46441 agaactctta gctctacttg tgagtaatcg gcatcaacca acttacagtt atcatctgca
    46501 ataaacactt ttcttatttt tctacccatt tccattttta taggtatatt ttgaagattt
    46561 ggttctgtag atgaaattct tcctgtagtc gttatagttt gattaaatga tgaatgtatt
    46621 ctattacttt ctggatttat tatatttaaa agtccttcaa cgtaagtaga atttaacttt
    46681 actatttgtc tatactcagt tatcttatct attattggat gcttatctct taatttttct
    46741 aaaacatctg cattagttga atatccagtt ttagtttttt taattattgg aagctctaat
    46801 ttttcaaata atataacacc caattgtttt ggtgaattta tattgaatgg ctctcctgat
    46861 aattcataaa tttccttttc tagtgtagct attatttctt taaactctac actcaattca
    46921 tccaatatac ttttgtctac ttttatacct tcatactcca tatgacctaa gacttctact
    46981 aaaggcatct ctacatgata aaaaagacca tccatactca tatccattag acttctttcc
    47041 atcataggaa ttgtttcttt aactgtgcat attatttgac ccatatactc tgctaaatcc
    47101 tcaaattcta aatcctcata gtttttagat ttaacaccct ttcctaataa ttcttctttt
    47161 gatttaacct tttttgataa atacttcata gctattgcac tacaatcata tgaggtagat
    47221 gaagttgaat ctattaagta ctcagctatt gttatatcaa aatacatatt ttctaagttt
    47281 atattatatg gttttaaaga tatataatca tcttttaaat tatatccata ctttttaatt
    47341 tcattatttg aaaatatact atctaacttt gacacttcat ttgaatctac ataatatatt
    47401 ttttctccat ctacacttat aaaaatatat attatatttt tttcaagtat attaccttgt
    47461 cctctaacag tttttaaaat aacttgtcct tttttgttta cttcatctat aaatttttct
    47521 gtatctttta attttaatat ttctattttt tcttctacgt gttctgtgtc atctgaatcg
    47581 accaaatcaa ctaatcttga taagagactt gtaaatccaa agtatctaaa tttatctaaa
    47641 agttcatctt tatcataatc gccaaaaacc atactatcta aatccacttc tattggcaca
    47701 tctcttataa ttgttgcaag tcttttactt tgaatagcta tttctttatt ttcctctatt
    47761 ttctttttta cactaccttt aagcttatct gtattctcta ttaaattctc tatactagaa
    47821 aactctttta taagctttat acctgttttt tcaccgattc caggtactcc aggtatatta
    47881 tctgacttat ctcccataag accttttaaa tcaataaatt gtgctggagt catctcgtat
    47941 ttttcaatta cagaattaaa gttgtattct tcaacttctc caactccttt ttttgttata
    48001 agagtagttg tattatctga agcaagttga atagcatctt tgtctccagt tactatgtat
    48061 accttatacc cattattttc tgctttttta gaaacagttc ctataatgtc gtctgcctca
    48121 tacccatcta tttccaatct atttattttg aatttatcta aaaggtcttt taatggctgt
    48181 aattgttctg ccagttcatc tggcattccc tttcttccag ccttatactc tttatattct
    48241 aaatgtctaa atgtaggtgc ttttctgtca aaggctacac ttatatgtgt tggtttatat
    48301 atatctatca ttttaaatag cattgttgta aatccatata ttgcattggt ctttaaccct
    48361 tctttattat tcatttctgg cagagcataa aaggctctgt ttattattga atttccatct
    48421 attataatta attttttttc caaattatat cactcctaaa aattatctat ttttgtaaca
    48481 tatatattat ataccaatat agtgttattt aatattccca taataataat agtatattaa
    48541 aattaaatat gttgcaaaca atatattttt ttgctataat aatatacatg acatgcccga
    48601 atggttgaat tggtaaatac aatggattca aaatcaactg tgttgattca taagttttta
    48661 taatgtttta cagtttgatg agtattttgt attcaatatt cctcttgcat attcttggaa
    48721 aatctggtag gatatacaag tagtttggat ttaaaatata agccgctgtg gcggaactgg
    48781 catacgcata cgactcaaaa tcgtacggga aaccatatgg gttcgagtcc catcagcggc
    48841 accaataaaa aaaactcttt agtatatact aaagagtttt tttattgtaa tattctttca
    48901 tctttatttc tagccttgta taagtataaa taccatagtc ataacttctt gaactcctaa
    48961 aatatatcta aacaaagtag gattttttat gtattcactt aataaatcca tacttcttat
    49021 catattgatt ttttcccaat ctctaaaaat tttgatacaa ataaaaaata cagagaacta
    49081 cttgatatac tagaaggtta ttctgtacca tttggtattg ctgtaggtgt tccagatgga
    49141 aatttaccaa atgctagaga tgtagtttat aaagtttcta gagtttagga taaagtgttg
    49201 caacaatcaa ttagttactt gaagagttaa atcagtaata tacaaataaa ttaatggaag
    49261 aggaagctat ttaaaaagta gtttagattt ttcattgtaa aataattaaa taaagaataa
    49321 ggtgataagt attttattta ttatcttatt cttttttatt tgtggaatga taaaaataag
    49381 aattaagtgt aatacaatgt aaataaaatg tgttaatttt aagtatattt tgtaaagttt
    49441 ataaaatctg aaaagctcaa gatatatttt cactataatg gataaaatat caaaatattg
    49501 aaataaacaa aaaataatga tataataaga aaaaataaag aaaaaaagta acccttagtt
    49561 gtaaaagggt tatttttttg tgataaaata tccataaaaa tattcatacc aaagtaaatt
    49621 aagatgtatt tcatttctca aaaatatcct aatataaaaa ataaagaaat atttataaat
    49681 ttaattatta gacatagata atatctaaaa aatataccaa tttcaacaaa tagtaacttt
    49741 tttacaacaa atggaaacta tggaagcaat aattaaaata aaatttataa tcaatcataa
    49801 ttatttagta taatgattcg atattatttt aaagtatttg tcatttaaaa caaacttgcg
    49861 ataaaagcat atctgaaagt attctgattc taatacttaa taaagagttc tttttacagt
    49921 tatagatata aacaacatct atcttaatag actgtataga ggcacaatca aaggtaaaca
    49981 catatagtta agtaatatgt ccttgatttt tctttattat aatagcttta ttaattcatt
    50041 ttaatattac atcattttaa aaaaattata tgaaaagtca aaatttacat atagattaat
    50101 taaacttgta aaaacacata taaattcata caattaagta cttaaaactt gaaaatactt
    50161 actttgctat atattttaga taaagatata attgatttgg ttaagaaagg agtctaatat
    50221 gatattcagt agtttaatat ttttattttt attctttcca gtcacactca tttgctatta
    50281 cttggcaaat cctaagtata aaaatgttat gttacttcta gcaagtattg cattctacgc
    50341 atggggagaa ccaaaatata tttttttgat gatactatca ataatagtaa actatatatt
    50401 tggtattaaa gtttctggca gtaaaaataa aaaaatgtgg gttgtgcttt ctgttattta
    50461 caatatatct attcttgctg tatttaagta tagcaatttt tttatagata atattaattt
    50521 tttattcaat acagatataa ctatacctga ggttaaatta cctttaggta tctcattttt
    50581 cacattccaa ataatgagct atgtaataga tgtatataga aatgatgcta aagttcaaag
    50641 aaaattagct aatttagcat tatacataag tttattccct cagcttgtag caggtcctat
    50701 tgttagatat cagactgttg cagatagcat tgagtataga gaacacaatt gggacaaatt
    50761 tactcaaggt gtaaacagat ttgttgttgg tcttggaaaa aaagtaattc tagcaaatca
    50821 attaggtgta atcgcagatg gtgtatttaa taagtcagct ggagatttat caagacttga
    50881 ggtatggcta ggtatagttt gctatacact tcaaatattc tatgacttta gtggctatag
    50941 tgatatggcc attggtttag gtaagatgtt tggatttgag tttttagaaa atttcaacta
    51001 tccatatatc tctcaaacag tatctgagtt ttggagaaga tggcatatat ctttaggtac
    51061 ttggtttaaa gactatgtgt acttcccatt aggtggaagt agagtctcta aggcaaaact
    51121 atatagaaat ctatttgtag tatggttttt aaccgggatg tggcatggag ctagttggac
    51181 ttttattata tggggtctat attatggaat attaatatca gtagaaaaag cattcttaga
    51241 aaaatttcta tataagatgc caagaattgt aagacacata tatctacttc ttatagtcat
    51301 gattggatgg gtatttttta gagttgatga tttaccagca gctattaaat ttataggtat
    51361 tatgtttggt gctggaaatt atccggttat cagtgatgca ttcaatgtat ttataattga
    51421 atattggtat ataattgttg gggcaatcct tctatcaact cctattgtaa aagttgtaaa
    51481 atcattatta attaagaaaa ataaaaatac attaaatagc acattatatc aagttactaa
    51541 tgtggttttc attgtttctt gtatgtttat tgtaataata atgttaagta gctcaaccta
    51601 taatccattc ttatatttta gattctaatt gggaggtata aacatgagta aaaaaaaacc
    51661 aaggattgtt gccatttcat ttttaattat agtatttgga tttttcatac taaacttcac
    51721 acttccaaag aaaaaattaa gtataactga aaatagaaat cttgcaaaat ttccgactgt
    51781 agaaaattta aaaaaatgtg actttatagc caagtttgaa gaatatttta atgaccattt
    51841 tgcatttaga gatgaaatga tatcaataaa tacaaggact caggctaatt taaataaaac
    51901 taaggtaggt aactattatc taggaaaaga taactggata ttaggtatgt ttccagaaat
    51961 tttagaccaa aaacaattaa gtcgatacga aaaatccatt aattatttat ctaatctaag
    52021 taaagatatg ggaaaaaatg tgtattttac aatgatgcca cataaaacta atatgttaaa
    52081 acatttgtat cctaaatatg ttgataatat ggataatata gacataaatt taaagaattt
    52141 taaaaataga ttaaatccag atttaattaa atatatagat atggatgagt attttttaag
    52201 taactattca gataaagaaa gagaaaattt atattttaaa actgaccatc attggactgg
    52261 atatggagca tttgaaggct ttaaaatgat ggcatcaaat atggacttag gtctatctaa
    52321 gcaagattta gacaagcatt ttagtagcta taaaaagtct ataattactg ataagaaatt
    52381 tataggaagt tataatcaaa atatagatat gctaattaaa gaaaatgaat atgtagttta
    52441 tatgacaaaa gataaccaag attatagctt tgatataaat ggagaagaaa aagaagaaaa
    52501 agaagaaaaa gaagtttatg caactgaaag agataataaa gagtgggatt atggtggtgc
    52561 atacattaga ggagctaaaa ctaatatatt aactataaaa aaccctaaag cattagtaga
    52621 taaaaaaata ctaatattta gagattcata tcaggctcct acaacacttt tatttgctga
    52681 tatgtttaaa gaagtagaga tagcagaccc tagaaatata aactcaatat ataaaacata
    52741 caaagagata atcgaggaaa gtaatgcaga tattgtaatg tttatgtata atagttctgg
    52801 gtttgattca atgatagatt caatgataga taaaggaata aagtagtaaa taaaaagcct
    52861 ctattaaatt caaaatttaa tagaggcttt ttattgttta ttttttattg ctttggtaaa
    52921 aataaactaa tcaaaataaa agtaaggaga tgtagcatat tgaacaaaag acatagtcta
    52981 cctatagtat cagtgatatt attgatggtc ttaattatct ttaataataa ccaaaattat
    53041 attacaatga aagaagtttt taatgtccat attatgcaga gtcaaaataa aaagattaaa
    53101 caaaagtatt atctaactaa agatggatgg ctattaggca actttgctaa attattatct
    53161 gattatcata taaaatctta ctccaaagcc attaataact tgagtaagtt aaatagaaaa
    53221 aaagattttt actttgtttc acttcctcat aagacaaata tgcttaagca cttgtatcca
    53281 agtggtatag aaggtaaaaa taatatagat attaacaaag aaaacttaga aaagcagtta
    53341 acagacataa atttcttaga tatagatgat tacttttata gaagttttac cgaaaaagag
    53401 agagaaaaat tctttttaaa aacagaccat cacggaaatt cattaggagc atttgaagaa
    53461 tataagttta ttcttgataa attagacctt ggcttatcta aatcagaaat agatagtcat
    53521 ttaaaaagat acagtactcg atatgtaaat gacaaggtct ttataggtag ttataataaa
    53581 aagatgggat atccacttaa gaaaaaagag tctataagct atgttgaaat aagtgatgca
    53641 aattacaaat attttattag taatggtact aaaaatactg agattaatga aaatatcata
    53701 aaagcaaaat taaaagataa aagagaatgg gactatggtg gagcttatat gagaggttgt
    53761 gattgtcaca tacttaagat tagaaattca agctctttaa ctaataaaaa ggcccttata
    53821 tttagagatt cgtaccaagc acctatgact tggatgttgg ctgatacttt taaggaactc
    53881 gaaatactag atcctagata tataaaaaat atagatatga cctatgatga gataattaaa
    53941 aacagtaatg cgaatgtagt tttatttatg tataatagct ttggatttgc tggaatgata
    54001 caagaaatga ttgacaaggg aatagcataa caatttgaat cagctccttt ttatacaaaa
    54061 aatagttctc aataattcct aatctatatg ataatttagt acatctcttt aacaataaaa
    54121 ataaaatcac aaaaattctt ataccatcac ttatctttat gataaattgg ttgagaaaaa
    54181 attttataat ttatatgata tgcaatctta attaattctt tatctactgc aacctttaat
    54241 aaaagaaacc atccaagact attaatatga atttatataa aaattacttt caaataaagt
    54301 actgcagtat ttttatttaa agtatctata atctttaacc acaaaaagcc acaaaataca
    54361 atgtatactt atggcttttt ataaatttat ataattgtat ataaagatat attctaaaac
    54421 tgtcttaaga atctaaagtt taaaaatcca atatttttat tgtgaattta aactttttat
    54481 tacaactttt tatctaattt attgtataca acaacactac aaataaattg aaataaaata
    54541 agcaatccaa gaacaactaa aacccacttg cttattacca ttacagaaaa tacactcaat
    54601 atagaaacaa taaatataag aattacaaga acataggaca tgatttgatt agtgatacgt
    54661 ccagctttat cacgtaacat aactcttctt tcatcattca tctctatcct ttggtttttt
    54721 atcttttctt cataatctac tgctctttca ggcttactcc aatacatata ttgaaaaatc
    54781 atacatatac ctggacctaa agcagctcca gataatcccc aaataaaagc ctcaaatgaa
    54841 aactcagtaa acgtagccaa taaaacaagt aaaattccac aaataaaata tactattcca
    54901 agatataaca tattcttttt catttttact cctcctcata aataaatatt tcttcaatac
    54961 tcatctgaac ctcccatgac taaagtcaca
//
LOCUS       DAEQJM010000019        54854 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.019, whole genome shotgun sequence.
ACCESSION   DAEQJM010000019 DAEQJM010000000
VERSION     DAEQJM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54854
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.019"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            58..1293
                     /locus_tag="KRQ43_001490"
     CDS             58..1293
                     /locus_tag="KRQ43_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBH2741852.1"
                     /translation="MGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITSGVTGMF
                     CHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLRGSLASLLEVESGSNDPIAY
                     MLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFYTIF
                     ITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIMLFF
                     MLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVGLRG
                     AASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTPVLK
                     TFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGSTII
                     KTGDILVLSGDRIEELIQL"
     gene            1369..2181
                     /locus_tag="KRQ43_001491"
     CDS             1369..2181
                     /locus_tag="KRQ43_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2741853.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRIL"
     gene            complement(2521..3702)
                     /locus_tag="KRQ43_001492"
     CDS             complement(2521..3702)
                     /locus_tag="KRQ43_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH2741854.1"
                     /translation="MKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYSWKLVP
                     TDKTPAGKRDDISLREKEKQIKKDLDDGIDTVGGKMTVCQLYEKKNNQRKNIKRNTEL
                     GRQYLVNALENDPLGMRAIDTVKQSDAKEWAIRMNGKGYSYKTIDNYKRSLKASFYMA
                     IQDDCIRKNPFNSKLSDVLEDDTEAKVILTPEQEEKLLAFMETDNVYSKYRDEVILLL
                     ETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISKAKTKNGKRELPLTERAY
                     QALKRILKNRGKAQPLVVGGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHKDKL
                     PNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELERLA
                     S"
     gene            complement(3683..3817)
                     /locus_tag="KRQ43_001493"
     CDS             complement(3683..3817)
                     /locus_tag="KRQ43_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2741855.1"
                     /translation="MYYFLEMSDTEIADIMNYTREAVFKHRHRALETMKEILNEKTRQ
                     "
     gene            complement(3817..4107)
                     /locus_tag="KRQ43_001494"
     CDS             complement(3817..4107)
                     /locus_tag="KRQ43_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741856.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELRRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKNVTMY"
     gene            complement(4373..4603)
                     /locus_tag="KRQ43_001495"
     CDS             complement(4373..4603)
                     /locus_tag="KRQ43_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741857.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            complement(4627..4818)
                     /locus_tag="KRQ43_001496"
     CDS             complement(4627..4818)
                     /locus_tag="KRQ43_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBH2741858.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            complement(4933..5073)
                     /locus_tag="KRQ43_001497"
     CDS             complement(4933..5073)
                     /locus_tag="KRQ43_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741859.1"
                     /translation="MEQYWWIIIVMVLIVVGLLKIVIMKKYNQRRNSNNRSKNSEDDK
                     MY"
     gene            complement(5126..6037)
                     /locus_tag="KRQ43_001498"
     CDS             complement(5126..6037)
                     /locus_tag="KRQ43_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH2741860.1"
                     /translation="MEKGRLLQNENINKAIQVSKITLIINLGLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVLSTIVVMVGIKISEKQPDKEHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSGQYNTLSVSSGIALTAAVLSIVIKEWMYWYTRSAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASIVICGCILKAALDIFKESINKMVDHS
                     CDNATETKIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELPYSP"
     gene            complement(6049..6747)
                     /locus_tag="KRQ43_001499"
     CDS             complement(6049..6747)
                     /locus_tag="KRQ43_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741861.1"
                     /translation="MKRILSSTIQVFKQIKSDPMMFAACFTPFVMGALIKFGIPFLDG
                     ITDFSLQTYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLMVALVW
                     YYFLIKRLFRKLAG"
     gene            complement(6744..7427)
                     /locus_tag="KRQ43_001500"
     CDS             complement(6744..7427)
                     /locus_tag="KRQ43_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2741862.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALTGHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKVSEYILSKTIALIAISTI
                     IAVILGFVSGSNHLLGIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIVCFV
                     PPIVGLFVKLPDIFRFFPFTACMNLITGKSILLSFDMVLVIATLIILYIVARHTVKHM
                     WRSLGGVKL"
     gene            complement(7424..8269)
                     /locus_tag="KRQ43_001501"
     CDS             complement(7424..8269)
                     /locus_tag="KRQ43_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2741863.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KILTGLNTSYKGSVKVAGTEIREHTNRFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     DKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNNRLMKDIILAEKKRGKTIIITTHNMYDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIHYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            complement(8373..8954)
                     /locus_tag="KRQ43_001502"
     CDS             complement(8373..8954)
                     /locus_tag="KRQ43_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2741864.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFSLYGLKKVTVDDLAAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTVKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEGLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMVQNLLVNGIIQQVVAE"
     gene            complement(9032..9889)
                     /locus_tag="KRQ43_001503"
     CDS             complement(9032..9889)
                     /locus_tag="KRQ43_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2741865.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERNSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPAWSHRFMGLIQLGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVASLFNADLSCLENG
                     AIQCPVILITAKGDPLFRFDYTNKVFDLIHVPKKELLTLELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            complement(10102..10995)
                     /locus_tag="KRQ43_001504"
     CDS             complement(10102..10995)
                     /locus_tag="KRQ43_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH2741866.1"
                     /translation="MFKKKEKPVKETKVRTMKVGTHKKSVIALWVVLIASVSFGVYKN
                     FTAIDMHTVHETETIQLRLNDTNGVENFVKNFCKSYYTWDNSKEAIEARTQAISNYLT
                     KELQDLNLDTIRTDIPTSSTVTNVLIWDIKQSGTNDFIATYEVDQQIKEGEQTSNVKA
                     TYTVKVHVDKDGDMVIVQNPTIAPAIEKSDYEPKAQEADASVDADTVNDATAFLETFF
                     KLYPTATEKELAYYVAGNVLEPIGRDYLYSELVNPMFTDDRDNVKVRVAVKFIDNQTK
                     AMQVSQFELVLHKDSNWKIIM"
     gene            complement(11011..12018)
                     /locus_tag="KRQ43_001505"
     CDS             complement(11011..12018)
                     /locus_tag="KRQ43_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH2741867.1"
                     /translation="MKLRHIAIVGSLFSILFSLVLFFGVLISAEDDDGGNGYSSNYVG
                     MNLSAEVLKHQPMVEKYAKENGISEYVNVLLVIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGISDINVVIQSYNYGGGYVGYVAGNGKKHMFNLA
                     ENFARDKSGGQKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLVVNQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYNKAGVSLPRTAQNQYDATQHIPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNTQMYHAGDPIGYADLNNAYWQQYLICAGRIK
                     Q"
     gene            complement(12015..14150)
                     /locus_tag="KRQ43_001506"
     CDS             complement(12015..14150)
                     /locus_tag="KRQ43_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH2741868.1"
                     /translation="MKERIKSVFTRKKIFRFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINTENLYSKYPLSNYQLDFYADNNWAWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     RLYLSNATGYVVQEAYKLDFINDMADSIGRSIQTLAGVTQNGFSTSGFYVGFLLLIIL
                     VVGIYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKVNDFSSDISTAS
                     LDLGTKIMLPDSDSKGKDSVDLIRDSLFSIQVQQPWLLLQFGNSGIEEIGADRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTILQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVYFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRLARAVSAGGVAGAVAGGVVASSKSTRQNGTKNNRGNTSSSMGQK
                     AGSAVGAVLDTKNKVKDKATAVKENIKDMPTQTAYAVHSAKEKAKSSVSDFKRGVVQE
                     KENRQSGRLKKQQLHRQNIADKRMELQKAQESRQAGKKTDGSATSGATRPHERPATTS
                     KVNVEKQQEVKRPAIASTVKNDEPIKKNVVKERPLSSGDTSAKTVNQETTRQNYKTDR
                     VTKTTVQKHTQQNTEKNKRTVFKKGQKKK"
     gene            complement(14150..16582)
                     /locus_tag="KRQ43_001507"
     CDS             complement(14150..16582)
                     /locus_tag="KRQ43_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2741869.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSSRSIQEQSKKLVTGRLKDVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTDQSMNLKSVKQSAFLTFKEFIHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLDKNDFGYLIEHIYGRDGVAYEDYEYSLPKKKLKKE
                     TLITHYDLIRPTRCLVEESQRHLRLEHEDSESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALSTVRNKKKELKDLDNHAYQSGSETSSNVVDALDSVD
                     ELETDLDQSRESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYIGYSVDTGRNVYLQPS
                     LASQGVKDTVTNALASAFVESLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDRENAGLLDPFVIMQNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRAVTQSDQRGLLHVIEELRKEDTPISCNIADHIDSFTDYDFAHLLFSDGTV
                     QNAISLDNQLNIIQVADLVLPDKDTTFELLSVSMLIVISTFALDFIHSDRSVFKIVDL
                     DEAWAFLNVAQGETLSNKLVRAGRAMNAGVYFVTQSSGDVSKESLKNNIGLKFAFRST
                     DINEIKQTLEFFSIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFEELLHAF
                     DTRPPIQRNEVE"
     gene            complement(16569..16958)
                     /locus_tag="KRQ43_001508"
     CDS             complement(16569..16958)
                     /locus_tag="KRQ43_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH2741870.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDLPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITFALRPKITY
                     AGKAVKLDKQVLHEAITAVRSVSYVPD"
     gene            complement(17071..17574)
                     /locus_tag="KRQ43_001509"
     CDS             complement(17071..17574)
                     /locus_tag="KRQ43_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH2741871.1"
                     /translation="MVEDMRVYIANLGKYNEGYLVGDWFSFPIDEEDVAERIGLNERY
                     EEYAVHDTENFPIEIGEYISIEELNEMYEMICELPDYITDSLDEFVSNYGSLEELYDH
                     RDDMILYAGCEDMTDVAYYFIDELQALGDIPPSLQNYIDYEAYGRDLSFEGTFIETRY
                     GMCEIPW"
     gene            complement(17590..18087)
                     /locus_tag="KRQ43_001510"
     CDS             complement(17590..18087)
                     /locus_tag="KRQ43_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH2741872.1"
                     /translation="MNEMRVCIESRLHTSEEIRSAWFTLPIDEEELEEQIGVPIDSED
                     YHIVEKELPFADEVGEDATIEKLNDLYHTFESLPADLQEDYGELMCYFTSLDELHQHR
                     HDVIHYSWCKNMADVARHLLDNDPAFSAIEERLTRYFDYEAYGQYLDDNGEFIETDHG
                     IYELP"
     gene            complement(18108..18296)
                     /locus_tag="KRQ43_001511"
     CDS             complement(18108..18296)
                     /locus_tag="KRQ43_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741873.1"
                     /translation="MKDIFSDMQASIGCTYISDLPHHKRMVWQEMKRLNLADYPQKQL
                     EDFAGYVFGVPYTSIAEA"
     gene            complement(18373..19011)
                     /locus_tag="KRQ43_001512"
     CDS             complement(18373..19011)
                     /locus_tag="KRQ43_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HBH2741874.1"
                     /translation="MEYKYTKIDLNKWNRGKLFQSYIDNMRIVMSLTVDIDVTKFIEF
                     SKKHDLKFYPAMIWAVSKVVNEHDEFKYSWDNNGNLIKWDYISPSYTEFHKEDENFTK
                     IVTDFSDSIFEFHKRFILDREKYKTERAFVENQSLNFFDVSCLPWVKYNHFDVHVFDE
                     GKFLAPVITWGKYELEQERYIMPLTMNIHHAVADGFHLSRFFNEVQELINSI"
     gene            complement(19331..19552)
                     /locus_tag="KRQ43_001513"
     CDS             complement(19331..19552)
                     /locus_tag="KRQ43_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741875.1"
                     /translation="MNFGQNLYTWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALVAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(19553..19687)
                     /locus_tag="KRQ43_001514"
     CDS             complement(19553..19687)
                     /locus_tag="KRQ43_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH2741876.1"
                     /translation="MWELIKDLLLVSLGMGIGVVLMCIMSVGKEADRHMIELKESEEK
                     "
     gene            complement(19694..20815)
                     /locus_tag="KRQ43_001515"
     CDS             complement(19694..20815)
                     /locus_tag="KRQ43_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBH2741877.1"
                     /translation="MAGISREHLSRIEAGKVALTEDMKHKLLEAVEKFNPDAPMFLLF
                     DYVRIRFPTLDIQHVIKDILKLNIDYMLHEDFGHYKYTEHYYIGDVFVYTSQDKEKGV
                     LLELKGKGCRQFESYLLAQERSWYDFLMDALVDGGVMKRIDLAINDRTGLLDIPELIE
                     KCKNEECISKFRSFKNYGSGELVKHNEANKDGMGHTLYIGSFTSEVYFCVYEKNYEQS
                     SKLGIPIEEVPIKNRFEIRLKNEHAYYAIRELLTHYDAELTAFSIINQYIRFADKEAN
                     KRKSDWKTNARWSWFIGEGRPPVKLTTKPEPYTLQRTLNWLQRQVAPTLKMLKQIDAG
                     NQMDYLKTIEQQAKLTDKHKQIIRQQTASVDELIEKEKE"
     gene            complement(21095..22489)
                     /locus_tag="KRQ43_001516"
     CDS             complement(21095..22489)
                     /locus_tag="KRQ43_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2741878.1"
                     /translation="MRMILNKGHRIRARDKNLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     RTDWEHFSLLDNGLTLSPYNFITILIATGICALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMENGLLHIHCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRISIDEVKAENGCLRLMKNLV
                     WEYDVLPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEDMIDCVNAFYEGMVQRSEEMKQHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAFVRQ
                     DGTATCEAKGDGTD"
     gene            complement(22599..23126)
                     /locus_tag="KRQ43_001517"
     CDS             complement(22599..23126)
                     /locus_tag="KRQ43_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcxB family protein"
                     /protein_id="HBH2741879.1"
                     /translation="MTNGGIPLETVELRFQYTQSEYIKAERQYLISSKTIHKYDIALV
                     AVFLLLSVVYMLFSSFSVFSILIFGLIIVVTALGSYLYILMPILKFKQTAKYHEEYTL
                     VFSKENIKFKTQSIDSEVKWDIYSALWESHDFYYLIQAPRLYTLIPKRIFKDLNEKQL
                     FEEIAQSRVKTTKHI"
     gene            complement(23162..23704)
                     /locus_tag="KRQ43_001518"
     CDS             complement(23162..23704)
                     /locus_tag="KRQ43_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH2741880.1"
                     /translation="MKGFERKNQLFSLCGLNCGLCPMLLGNYCGGCGNGNQSCRIAKC
                     SLEHGQIEYCYECKQYPCEKYQHIDDYDSFITHKRRKADLERAKNIGIEQYNLEQQEK
                     TQILSYLLSNYNDGRRKTFFCVAVNLLELSELQEAMKQIQSNDELTLLPFKAQCLYVV
                     EVFQKIAERRNIKLKLFKKK"
     gene            complement(23729..24187)
                     /locus_tag="KRQ43_001519"
     CDS             complement(23729..24187)
                     /locus_tag="KRQ43_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH2741881.1"
                     /translation="MKLKNPMLVVTDIDKSVEFYKKVFGLYVIMDFGANKTLTGGLAL
                     QTSETYKEFIGTSDISFGGNNFEVYFEEEDFDKFADRLKEYDIEYVHPIIEHSWGQRV
                     VRFYDPDKHIIEVGENMKIVCKRFLNSGMTPEQVAERMDVPMKFINACMR"
     gene            complement(24294..24707)
                     /locus_tag="KRQ43_001520"
     CDS             complement(24294..24707)
                     /locus_tag="KRQ43_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH2741882.1"
                     /translation="MLDKIPNAEEMTALVGQSLYSVWNELCALIDEKYEMECLWNKGG
                     KAWNYEYKYRRGGKTLCALYARENCVGFMIILGKDERLKFDTYRDNYSKEVQRIYDET
                     KTYHDGKWLMFEPTDTTLFDDFVKLLRIKRKPNRK"
     gene            complement(24803..25186)
                     /locus_tag="KRQ43_001521"
     CDS             complement(24803..25186)
                     /locus_tag="KRQ43_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH2741883.1"
                     /translation="MRLTNGIVLDNEKTFGVLKFSALRHEVRVENEDGTTSDEIKRRT
                     YDLKCSVQERMIQVSIPADVPVKDFPYNAEVELINPVADTVANANFRGTTVDWYIKAD
                     DIVLKNKGGQAGNPQNNAPQGQQKK"
     gene            complement(25201..25524)
                     /locus_tag="KRQ43_001522"
     CDS             complement(25201..25524)
                     /locus_tag="KRQ43_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH2741884.1"
                     /translation="MELKYIVPNVAQTFGNLEFAGENKVDQQRINGRYTLVSRSYNLY
                     SDIQRADDIIVVLPAKAGEKHFKPEQKVKLINPRITAEGYNVKGRGFTNYILMADDML
                     PAESK"
     gene            complement(25749..28409)
                     /locus_tag="KRQ43_001523"
     CDS             complement(25749..28409)
                     /locus_tag="KRQ43_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBH2741885.1"
                     /translation="MKKILKRLCTGFLAFATVVTALPSSTVHASNTQYWTESKERVSI
                     VEQVMNDGSISSTFNEGHLTVEGEDAYCIDINTAFKNGYKTKADASTRMSADQIADVA
                     LSIEYVKQYTDIHSGISSKHAYLLRQLVVWQRLSVQPDWQWDNVRASYDEIPKAVQDE
                     VFAGAKAFVKENKGRYDCGGYIYSGEGQELGQFWAKLAVGNTKLQKTSTNANITDGNG
                     IYSIAGATYGVYSDKDCTKQLTTLTTDTSGNTEAVEVRATIVYIKELSAPAGFKIDKT
                     VYSLSVEVGKTATLKVSDTPKVTDTLIELFKIDMETQKSNPQGNASLEGAEFTWNFYA
                     GYYNKNNLPAQPTRTWVTKTIAEKDSDGAIHYITRLADKYKVSWDSFYTQDGKNVLPL
                     GTLTVEETKSPSGYLLEGTYMQADGSEEQIKGMYLTQITEDGDLAVLSGSNQYHVSDK
                     VIRGGVKIQKRDLETKDTKAQGGATLKDTAFEIISLNENAVLVEGKLYKKNEVLKTIH
                     TDIEGIASTSADLLPYGKYRLSEQKPPEGYLTDGAKPIDFEITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGSHKRLADVPFRITSKTTGESHVVVTDDNGQFSTASDWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALLYDTYIIEELRCESNKGFKLIPPFEIVISRN
                     KVVVDLGTLTDEYEKEITIHTTATSKDGEKTILAGKDVTITDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIINDKRIENDYIFTADSETMEVKIEFTFDASNLGGKQLVTFEELYD
                     LSNPDEPIKVAEHKDIEDDGQTVTIKEVPETPTPEEPEKPTTPDTPTKTDSPKTGDNT
                     NILAFAIMMFVSAGGLAGTYFFKHRKMKKS"
     gene            28958..29575
                     /locus_tag="KRQ43_001524"
     CDS             28958..29575
                     /locus_tag="KRQ43_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBH2741886.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFIYIYMGKEFGAKRNNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDREQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(29732..30184)
                     /locus_tag="KRQ43_001525"
     CDS             complement(29732..30184)
                     /locus_tag="KRQ43_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HBH2741887.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            30632..31990
                     /locus_tag="KRQ43_001526"
     CDS             30632..31990
                     /locus_tag="KRQ43_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2741888.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTIMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            32263..32643
                     /locus_tag="KRQ43_001527"
     CDS             32263..32643
                     /locus_tag="KRQ43_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH2741889.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            32768..32968
                     /locus_tag="KRQ43_001528"
     CDS             32768..32968
                     /locus_tag="KRQ43_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741890.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            33164..33892
                     /locus_tag="KRQ43_001529"
     CDS             33164..33892
                     /locus_tag="KRQ43_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2741891.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            33914..34831
                     /locus_tag="KRQ43_001530"
     CDS             33914..34831
                     /locus_tag="KRQ43_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HBH2741892.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            34973..36157
                     /locus_tag="KRQ43_001531"
     CDS             34973..36157
                     /locus_tag="KRQ43_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH2741893.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            36264..36452
                     /locus_tag="KRQ43_001532"
     CDS             36264..36452
                     /locus_tag="KRQ43_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH2741894.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            36602..37252
                     /locus_tag="KRQ43_001533"
     CDS             36602..37252
                     /locus_tag="KRQ43_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH2741895.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEELSESEPTYIVENVESIKDILL"
     gene            37355..38293
                     /locus_tag="KRQ43_001534"
     CDS             37355..38293
                     /locus_tag="KRQ43_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH2741896.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            38319..39170
                     /locus_tag="KRQ43_001535"
     CDS             38319..39170
                     /locus_tag="KRQ43_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH2741897.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDTIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKNFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(39455..40189)
                     /locus_tag="KRQ43_001536"
     CDS             complement(39455..40189)
                     /locus_tag="KRQ43_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine biosynthesis protein TtcA"
                     /protein_id="HBH2741898.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMIYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            40315..41031
                     /locus_tag="KRQ43_001537"
     CDS             40315..41031
                     /locus_tag="KRQ43_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH2741899.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            41165..41857
                     /locus_tag="KRQ43_001538"
     CDS             41165..41857
                     /locus_tag="KRQ43_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2741900.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            41847..43028
                     /locus_tag="KRQ43_001539"
     CDS             41847..43028
                     /locus_tag="KRQ43_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBH2741901.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKLLYFNSEI
                     SVINQLVYQLRDFRSLIGESLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKMEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            43310..43765
                     /locus_tag="KRQ43_001540"
     CDS             43310..43765
                     /locus_tag="KRQ43_001540"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBH2741902.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            43755..44480
                     /locus_tag="KRQ43_001541"
     CDS             43755..44480
                     /locus_tag="KRQ43_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HBH2741903.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLNQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            44452..46833
                     /locus_tag="KRQ43_001542"
     CDS             44452..46833
                     /locus_tag="KRQ43_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HBH2741904.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDNAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSCGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(47038..48267)
                     /locus_tag="KRQ43_001543"
     CDS             complement(47038..48267)
                     /locus_tag="KRQ43_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH2741905.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            48867..49781
                     /locus_tag="KRQ43_001544"
     CDS             48867..49781
                     /locus_tag="KRQ43_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741906.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGVKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            49805..50440
                     /locus_tag="KRQ43_001545"
     CDS             49805..50440
                     /locus_tag="KRQ43_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HBH2741907.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTAQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            50816..51532
                     /gene="pyrF"
                     /locus_tag="KRQ43_001546"
     CDS             50816..51532
                     /gene="pyrF"
                     /locus_tag="KRQ43_001546"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBH2741908.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVRAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGADFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            51558..52601
                     /gene="carA"
                     /locus_tag="KRQ43_001547"
     CDS             51558..52601
                     /gene="carA"
                     /locus_tag="KRQ43_001547"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH2741909.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGEILTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIAPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            52654..>54854
                     /gene="carB"
                     /locus_tag="KRQ43_001548"
     CDS             52654..>54854
                     /gene="carB"
                     /locus_tag="KRQ43_001548"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HBH2741910.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYL"
BASE COUNT        18752 a         8758 c         9800 g        17544 t
ORIGIN      
        1 ctgtgacttt agtcatggga ggttcagaac tatgaattaa caaaacaatt atgttctatt
       61 ggactaatat ttataatgtt ttttggaggg tttggaacaa actggaatat ggctaaacct
      121 gttgctatac cttctatatt aatgtcttca ctgggtgtaa taattacgtc tggggttaca
      181 ggtatgtttt gccacatggt aataggaact agtttacttg aaggtttatt aattggggca
      241 attgcagctt caacagatgc tgcatctgtg tttgctgtgt tgcgttcaca aaaactaaac
      301 ttaaggggtt cacttgcatc attattagaa gttgaaagtg gaagtaatga cccaatagcg
      361 tatatgttga cactaattct tttgacattg atgaataatt ctggggtaga acttattgca
      421 ccaatggtaa taaaacaaat agcttttggg ttagctatag gatttatact agcaaaatta
      481 tctgtttata ttttaaggca ttcaaacttc gagatagaag gattttatac tatatttata
      541 acagctattg caatactttc ttatgcattt agcgagtatc ttggaggaaa tggatattta
      601 agtgtttaca tttcaggtat tattatagga aatagtagga tacctcttaa aaaaagtttg
      661 gttcatttct ttgatggaat ttcatggatt atgcaaataa tgttattctt tatgttagga
      721 ttgttatctt tcccttctaa gttaccaaat gtatttggta tagcaatggc catatctata
      781 ttcatgatag ttattgcaag accattagca acatttatag ttctagcaaa atttaaattc
      841 tcaaataaag aaaaattatt catatcgtgg gtaggtctta gaggtgcggc ttcagtagtt
      901 tttgcaattt atgctgttac tcaaggagta gccatagaga atgacatatt ccatataata
      961 ttttttatag cgttgctttc agtaggaata caaggttcat tgataccaac tgtagccaga
     1021 aagttggatt tagttgatga taatacacct gtattaaaaa catttaatga ttatgatggg
     1081 gaaattagct ctaaacttat cgaagtaaat gttgatgagg gtaataaatg ggctaataag
     1141 agtataatag attctaatat accagacgat atattaatag ttatgataaa aagaaaggaa
     1201 caggttttaa tacctaaagg ttcaaccatt ataaaaacag gggatatttt ggtattgagt
     1261 ggagatagaa ttgaagaatt aatacaatta taatttattt tgtattgact ttaacctaag
     1321 gggaaagttt aaacttaaat taatcaaatc taatgcgcag gtgatgagat gttttctata
     1381 ggaatgtttt ctaaaataaa taaaataact acaaagacat taaggtatta tgaagatata
     1441 gggttgttaa aaccagaata tgtagatgaa tttacaaaat ataggtatta tacaacagag
     1501 caattaccta aattacatca gataataact ttaaaacaaa tgggtttatc attagctgag
     1561 ataaaaaaag ctgtagaaaa tcctgaagaa gttgaaaata ttttaatgaa taaagaaaaa
     1621 gaaatgttgg atgtaattaa aagtgaagaa tataaaataa ttaaactacg taattacctt
     1681 atgaatttga aaggagaagt caatatgaat gatgtaatta ttaagtcttt accaaaagtt
     1741 aaagttgctt ctatgagaaa agtgttaaag ggatatgatg aactttttaa tctatttcca
     1801 aatgtaatgg ctgaagaaat gatgaaaaca gggtgtacat gtgcagttcc tgattattgt
     1861 tttaatatat atcatgatgg tgaatataga gagactgata tggatgttga aatgtgtcaa
     1921 gctataaatg atttaaagga agatacggat atattaaaat ttaaagaatt agatgcagtt
     1981 gaaaatgcag tttgtatatt acacaatggt ccatattcaa cattaggaaa aacttatgca
     2041 gatgcattta aatggataga ggacaataaa tataaagtgg ttggaaatcc tagagaatct
     2101 tatatagatg gtatatggaa taaagagagt gaagaagact ggttgacaga agttcagata
     2161 ccagtgaaac gcatattata atatgtctac aaagtataaa taagaataaa aaaggtagtg
     2221 tctcaaagta aactttttag tttatgagac actctttttc atatgaaatc aagtgtattt
     2281 ttataattcc gattatgaaa aaaggcttat ctctattttt ggacagcctc ttattttttt
     2341 attataaaaa cttactaaat ttctgattat cttttcataa gttggtagat gccgatatat
     2401 cccgcatttt cgggctgtat gggcattttc tttttggaag ataccttgca taagctggca
     2461 tttaccagca tgaaaatgca accaaaagta gtaaataagt agtaagatac attttcgata
     2521 ttaagaagcc agcctttcta actctgcctt tgcagactgg aaagtaccgt gagcataata
     2581 ccctaatgtc atggttatgt ttgcgtgtcc catgatgtat tgcagggtgt ttgggttcat
     2641 tcccttattt gccatgttcg tacagtaagt atgtctgaat gaatggggcg tgatgtttgg
     2701 taacttgtcc ttatgggtct tgttgtactt cttaatcaac ccacgcacca tactttcata
     2761 atttcctgct acctttggca atccctcacg gttcaagaat aagaaattgc tataaccacc
     2821 aacaacaagc ggttgtgctt ttcctcggtt ctttaaaatt cgcttgagtg cttgatatgc
     2881 tctttctgtt aatggaagct ctcgcttacc gttttttgtc ttagctttgg aaatatagta
     2941 gcccacctct gtatcacgca atagctggtg gtctatgtta atcacacggt taagcatatc
     3001 aatgtgtgtt gtcagtccgc ataattcaga gatacgaagt cccgtttcca gcagaagaat
     3061 aacttcatca cgatacttgc tgtaaacatt atctgtttcc ataaaggcaa ggagtttttc
     3121 ttcctgctct ggtgtcagga taacctttgc ttccgtatca tcttccagaa catcactcaa
     3181 cttggaatta aaaggatttt ttctgataca gtcgtcttgt atcgccatat agaatgaagc
     3241 ctttagggaa cgcttatagt tatctatcgt cttgtaagaa taacctttgc cattcattct
     3301 gatagcccat tctttagcgt cggactgctt gaccgtatca atcgccctca tacccaatgg
     3361 gtcattttcc agtgcgttca caagatactg tcgtcctaat tccgtgtttc tcttgatgtt
     3421 ctttctttga ttgttctttt tttcgtaaag ctggcagact gtcattttac cgcccaccgt
     3481 gtcgataccg tcgtcaaggt ctttttttat ctgcttttct ttttccctca acgatatatc
     3541 atcacgtttt ccagcaggtg tcttgtctgt gggtacaagc ttccaagaat atacaaactg
     3601 tggcttcccg aatatatcgg tatatttata aacgtatctt ccgtcttttc tctggctctc
     3661 tccaagacgc aaattgcgtc ctttactgtc ttgtcttttc atttagtatc tctttcatag
     3721 tttctagtgc acggtgtctg tgtttgaaca cagcctctct ggtataattc ataatatctg
     3781 caatctctgt atcactcatt tccaagaagt aatacatcaa tacattgtta cgtttttttc
     3841 gggtagctgt ttgagagctt ctgcaagttc atcatcaagg actttaatat ctatgccaca
     3901 cacattaaaa attgtgtagt ttgtttcgta gtcgtcccat gttgccagac tttctaccgt
     3961 aatgtctggt aattcgctaa aagatatttc cttgtttttt cttcgtctta attctttgcg
     4021 gtagttccag ataatacctt tgacaacttt tttcagctta cattcaaact gacactgaat
     4081 tgttttttgg aagtcagacg gtttcataat ctcacctcct ttccagctat gaattgaaaa
     4141 gtgtttatcc ctctttccgc accatatctg tacagcaagg tgtgatttgc ttccaaaaaa
     4201 atgaaaataa ttaaaaaact tttcgggtat taaaaaagcc cgcacaaaat ataaattttg
     4261 tacgagctac tggtatagcg tatttaattg taaatagtat gctgttaaat tgggcttgaa
     4321 tatactgaat tgtatttaaa gcgtttcata cggcaagccc cctttacaac atttaaacct
     4381 taacctttgt ctttttggta atcgtataaa tatattcctc tggtgttggc cgcttatttc
     4441 caaagtatcg tttaaaattt gcctgcacgt ctgggtctgt actttccata gttttgtcta
     4501 tggtatcttg tagcatagcc ctaaattcag atacagaaac accttgagct ttagcaccaa
     4561 ctttcataat ataattcata tctcgtcttt taagtcctat cattagaacc aactccctaa
     4621 aataagttaa tcttcttttt caaaaattaa atctatcttt cgcatacagc cttttgcgtc
     4681 aatttctgtg ggtacaaacc ctgcgtagtg ataccccgtt tttgcataac tgtcaataat
     4741 ttctttgtgt ttatcagtac aaaggaatac aactcctttc gcattataat taatttctac
     4801 atactcatat tttttcattc ttcaaaactc ctttcaaata caaatttatc tttggattta
     4861 ttgactttta caaactggga tttatcgttc aaatttcata ggtatatatc tcataccatc
     4921 ggataattgc tcttaataca tcttgtcatc ctcgctattt tttgaacgat tgttagaatt
     4981 tctcctttgg ttatacttct tcataattac aattttaagt aagccaacga caatcaaaac
     5041 cataacaatg ataatccacc agtattgttc cataacctac ttcccctcct ttccctttca
     5101 atagtcttaa atcatcttcc ctgtcctatg gagaataggg aagttcattc gtattaacat
     5161 gtaccataca atgtttacat tgtggaaagt tgttttcaat cgtttgatgg actccctcag
     5221 caattctatg agcgtcataa agagctaaat taccatcagc taatatttca atatctacat
     5281 acattttcgc tccaaacatg cgggttttta attcatcaat accatcaacc ccttgctgct
     5341 gaagcacaac ttccctaatc ttcgtttcag tagcattgtc acaactatgg tctaccattt
     5401 tgttaatgct ttctttgaaa atgtccaaag cagcttttaa gatacaaccg caaatcacaa
     5461 tgcttgcaat agggtcgaga atagcatagc ctaaacgtgc tcctaaaatg ccaattaagg
     5521 aaccaaccga cgagagtgca tcagagcggt gatgccatgc gtcagccata agtgcgtcag
     5581 aatttgtatg ctttgcagca cttcttgtat accagtacat ccactctttt ataacaatgg
     5641 ataagactgc cgccgtaagt gcgattccac tagagacaga aagcgtattg tactgtcctg
     5701 aaaagatttt cttgatacct gaatatccta ttccagcacc cgttatagcc aatgcaacag
     5761 agagaataat ggaagccaca cattccatac gttcatgccc ataaggatgt tctttatcag
     5821 gctgtttttc tgatatttta attccaacca tcacaacgat tgtgcttaat acatcagaag
     5881 ccgagtgtac agcgtccgac agcatggcac ttgactttcc tatatatccg gcagcaaatt
     5941 taagtagcga taaacccagg ttgatgatta gtgtgatttt ggaaacctga atagccttat
     6001 ttatattttc gttttgcaga agtctacctt tttccataat atgccttctt atcctgccag
     6061 cttcctaaac agacgtttta taaggaagta gtaccagacc aaagctacca tcaatcctat
     6121 ggagaaataa agaaccgctt cattctgcat ggctttcgct acccaaaatg atggaaggaa
     6181 gccaaccgcg aactggtagt aactatcaat aaaaaaggga gctggtattc cgagtaatgt
     6241 aagtgcagct agttttgtaa ctgccatacc ctctaattta ttgcttgata atgttataat
     6301 cataagcgaa acaataattg cctgtactga gccgagaagc gccaaacata ttgtcattcc
     6361 aatggacaac ttttctaatg aaaaaagcaa cagtacaata aaagcgatga ccgccgaaat
     6421 aattgagggt actcccaacc ttgtaaagag ataccccgac ttaccaagag gggtaatcga
     6481 aaagtaccgt gacactttat cgtcgatttc ctctaatgta atcattgcaa atgcaaagca
     6541 gagcaataca ggagccatga tagaaagtaa taaatcaaag atcggatagt atgtttgcaa
     6601 agaaaaatct gttattccat caagaaaggg aataccgaat ttaatcaaag ctcccatgac
     6661 aaaaggcgta aaacaagctg caaacatcat agggtcgctc ttgatttgct taaatacctg
     6721 tatggtactg gataatatcc ttttcatagc tttacacctc ccaaacttct ccacatatgc
     6781 ttaactgtat gtcgcgcaac tatgtagagg ataatcaacg tagcaattac aagtaccata
     6841 tcaaacgata gtaaaatgct ttttccagtt atgaggttca tgcaagctgt gaacggaaaa
     6901 aagcggaata tatctggtaa ctttacaaac agaccaacga taggtggaac aaagcaaaca
     6961 atttctatcg gcataatcac aatgagaaat tggttcaagt ttgaaatttt tgtagccgcg
     7021 ataatgccaa gcatagtaaa gattgctgat gtcaaagctg taccaactgc gataccaagt
     7081 aaatgattgc tgccggaaac aaatcccaat atcaccgcaa tgattgtaga aatagcaatc
     7141 aatgcgatgg tttttgaaag tatatactcc gatactttta caggcgatac taccatagca
     7201 tttaatacct tttggctttt ttctaaaagg acaatcgccc ccataaaaaa caatcccata
     7261 gctgccgggt cagagtatat catgatagaa gcaatatccg ttttccaatg tcccgtcaaa
     7321 gcggcaatcc cacacacata taaaactgtt aatataaagt agataaaata gaaaccatat
     7381 ttccattgga aatgtatatc accacaaatt aaacgtccca atctcattga agtgtcctcc
     7441 ctgtaatatc aacaaaaata tcatttaatg taggctcact actatgaata gaaagcagac
     7501 ggttttcgga aattaaactt tttaacaact tatcttctgt ggttctatca agcagacatt
     7561 ctccggtttt ctcgccttta tcatagtagg tatagtgtat tttggcagct ccccttgaca
     7621 taatcaaatt atgtggacta tccaatgcac tgacttttcc ggcaacaata aaggctactt
     7681 ggtcacatag ctctgttgcg tcatacatat tgtgagtagt aatgataatc gtttttccgc
     7741 gtttcttttc cgcaagaata atatctttca ttaaacgatt atttgtaggg tcaagaccgc
     7801 ttgtaggttc atcaaggaat aatatatcag ggtcatgtac taacgcttta atgaaattca
     7861 agcgagaacg catacctttg gaaaagtcag caactttttt gtccccatca ttttctaagc
     7921 ctaccatatg caataattca tcaatagacc gaggttgctt gtcatataga gaagcaaaat
     7981 aggcgagatt ttgtcgtgct gtgaatttct cgtagcaggt tgaaaattca aagtctactc
     8041 caatattttc ataaaaccgg tttgtatgct cccttatttc tgtacctgca acttttacgc
     8101 tgcctttata acttgtatta agcccagtta aaattttttg aatagttgat tttccagcac
     8161 cagagggtcc taaaaaaccg aaaatttctc ctctcccaac atggaaactt acattctcaa
     8221 caaacggttt gtcagtataa ctaaaataca gtttttttac atcaatcatt attctttcct
     8281 cctttaactt tatgacgttt atagatatat agtcatataa actgtaaaaa atttgtttgg
     8341 ccacttgcct gtcaaataac caaacaaaat tattactctg ctactacttg ctgaataata
     8401 ccattcacta aaagattttg taccatattc aattcttcgt cctctttgaa ttgttccaaa
     8461 caggataaaa cagaatacag ggattttatg ataaccgtat gcggaaccaa aaatacaacc
     8521 cctaaacctt ccagtatctc caatatacga atatcactgt acatatgatt ttcaaaaata
     8581 tctgacgata tttttctttg cagatagtcc attaaagata aatcaatctg tgaaagaata
     8641 ggcgaagtaa tcacccccgt taaacttagc ataataacgt cctttgctaa atctctatgg
     8701 ttcttatact ttttcttttt aacagttgtt tctatacttg taaataactc tttttgtaag
     8761 cgaaaattga tttccacata tagatgttct ttactgggat aaaaagcata gaatgaacct
     8821 tttgatatgt ttacagcagc tgctaaatca tcaactgtta ctttttttaa gccgtataat
     8881 gaaaacagct tttctccctc tatcaaaagt ttactgttta tgatttcttt ttcttgttcc
     8941 gtaaatcgtg gcaaactcat aaccccctta tgactaaaat gtttttatcg tcatgaaaag
     9001 tataacattt actgattata taatcaatat actatccaag atatttatgc aaggtagctt
     9061 ccaatgcgtt tattgtagtg tccgtgtcct cattaaaaat catgtgacga ttaagctcta
     9121 aagtaagtaa ttcctttttc ggtacatgaa ttaaatcaaa tactttgttg gtataatcaa
     9181 atctaaaaag cggatcgcct ttggcagtaa ttaaaataac aggacattgt atagccccat
     9241 tctccaagca cgataagtca gcattaaata agctggcgac aaatcttaaa ggataatagg
     9301 gtaaaagcat agggtcattt aagcaatctt gttttgcctg ttcactataa aatactctgt
     9361 catagtctaa ataagcgtct cctggaacct tatagttagg cagcaatttt ccacctacac
     9421 gaaagcccaa ctgtatcagc cccataaaac ggtgtgacca tgcggggtat tttgttaagc
     9481 tcatagtttc ttttaatgta gtcagcatga tattatgtgg aaaaacggct tttaaccttg
     9541 tgtccctacc cgccgccatt gcagctaaaa tcccaccttg actggaaccc atgacagcta
     9601 tgttttcacc aaaattttct attccgtaag tcgttgcgtc atatacatta tgcagcaaat
     9661 cttccattgt ataatttttt ttgattttag ggctttttcc gtgtgaaaga tagtgaatgc
     9721 ctattatatt aaatcctctt tcactcaaac cacatagaaa attctcatac atgagagggt
     9781 gtgacatagt acccggcaaa aaaacaatgg taggactatt tctttctgta taccaaatag
     9841 aaagtgttat cggaacatta tttgaagaaa taccaacttc tttatacata ccacacgcct
     9901 cctatatgac taatttagtt ttatagtcat attataactt attgcaagca gaaagtcaat
     9961 atccataaat atatgattta agataaaatt gtcaagaaag atttaattgc ttaaaataca
    10021 atgaaatcgc ttgttagtgc agcacatttg ctatagaaaa ggcagactat atccgaaaat
    10081 agagcctgcc aacaaaatat cttacataat aattttccag ttgctatcct tatgtaacac
    10141 aagctcaaac tgtgatacct gcattgcctt tgtctgatta tcaatgaatt tcaccgcaac
    10201 cctgactttc acattatccc tgtcatccgt aaacatagga ttgactaatt cggaatagag
    10261 gtagtccctg ccgataggtt caagcacatt gccagccaca tagtaggcaa gttctttttc
    10321 tgttgctgtc ggatacagct taaagaaagt ttccaaaaat gcggtagcgt cattgacggt
    10381 atctgcgtcc acgcttgcgt cggcttcttg tgcctttggc tcatagtctg atttttcaat
    10441 cgctggtgca atggttgggt tctgtacgat aaccatatcg ccgtctttat ccacatggac
    10501 tttgacggta taggttgctt tgacattgct tgtctgttct ccctctttta tctgctgatc
    10561 tacttcgtag gtagcgataa aatcgttcgt tccagactgt tttatatccc aaatcagtac
    10621 atttgtaaca gtggagcttg tcggtatatc cgtcctaatg gtatcaaggt tcaagtcctg
    10681 caactccttt gtcagatagt tgctgattgc ctgcgtcctt gcttcgatag cttccttgct
    10741 gttgtcccat gtgtagtagg acttacagaa gttcttcaca aaattttcaa ctccgttggt
    10801 gtcatttagt cttaactgaa tggtttccgt ttcatgtacc gtgtgcatat caatggcggt
    10861 aaagttctta tacacgccaa atgatacgct ggcgataagc accacccaca gagcaatcac
    10921 agatttctta tgtgtgccta ctttcatagt gcggactttc gtttctttta ctggtttttc
    10981 tttcttttta aacatggttt ccaatccttt ctactgtttt attcttccag cacaaatcaa
    11041 gtactgttgc caataagcat tgtttaaatc ggcatatccg atagggtcgc ctgcatgata
    11101 catctgagtg tttcctacat agataccgac gtgggttaca tagcttcctg cattgtaggt
    11161 actgtggaaa aagaccaaat cgcctgcctt tgcctgcgat agtgggatat gctgggttgc
    11221 gtcatactga ttttgtgcgg ttctcggtaa agatacgcca gctttgttgt agcaccactg
    11281 taccagtccc gaacaatcaa aagaagtgtt cgggttactg ccaccatata catacttcca
    11341 accttgatat tttaaggctt cattcataac cttttgtgcc agctcgcccg atacttgatt
    11401 gacaacaagg tactggttca caagctccac atagaacata tttccatagc cataacgcca
    11461 gccaccattt tttgccacgg cgatagggtt cgtataggtt actttttgac cgcccgactt
    11521 atcccttgcg aagttttccg caaggttgaa catatgcttt tttccgtttc ctgccacata
    11581 gccaacatag ccaccgccat agttatagga ctgtatcaca acatttatat cactgatacc
    11641 ttgatttttg caggaagaaa gcagggacgc aaaatattta cacccctgct tgattgagct
    11701 ttccgtatct agtgagttgg gtggtagtcc cagactttca gagctttgca taacgtcctc
    11761 ggctgtaccg ccactttcca cttgtatgat taccagcaac acattgacat actcggaaat
    11821 accgttttct ttggcatact tttctaccat aggctgatgt ttcaagactt cggcagatag
    11881 gttcatacct acataattag aggaataacc attgcccccg tcgtcgtcct cggcactaat
    11941 cagaacccca aagaataata cgagagaaaa gaggatagaa aacagactgc caacaatagc
    12001 gatatgtctt agtttcattt cttcttttgt cctttcttga atacggttcg tttgttcttc
    12061 tcggtattct gctgtgtatg cttctgaacg gttgttttcg taacacggtc agtcttgtaa
    12121 ttctgtcttg tggtttcttg attgacggtc tttgctgatg tatcgccaga agatagtgga
    12181 cgttccttga caacattttt cttgataggt tcatcattct tcacggttga agctatggca
    12241 gggcgtttga cttcctgctg tttttctaca ttaaccttag aagtggtagc tggtctttca
    12301 tggggacggg tagctccgct tgtcgctgat ccgtccgttt tcttacctgc ctgccttgat
    12361 tcttgtgcct tttgaagttc catacgcttg tcagcgatat tctgtctatg tagctgttgc
    12421 ttctttaagc gtccagactg gcggttttcc ttttcctgca ccacgccacg cttgaaatca
    12481 gacacactgg acttcgcctt ttccttagca gagtgaaccg cataggcagt ctgtgtcggc
    12541 atatctttga tattttcttt gacagcagtt gccttgtcct tgaccttatt ctttgtatca
    12601 aggacagctc ccacggctga acctgctttc tgccccatgc tggagcttgt atttccacga
    12661 ttgttctttg ttccattctg gcgtgtagat tttgaactgg caacgacacc accagccacc
    12721 gcaccagcga caccaccagc actaacagct cttgcaagcc tatgttccat acgtctagcc
    12781 ctatgtcgca tgaacagata cggtctgcgg aatattcgcc gtcccatgct ttgactgtcg
    12841 ccagcgttta aagagaacat gctcattaaa tcgcccagct tcatgtagat acctgcaaaa
    12901 tacactatct gcaagaacgc caccataaag aacgggtagt ccgtcgatat gttgtagaac
    12961 atactggaaa tactaaaggc taccgtgaca atcagtgtaa tacctgccct tgtcataatc
    13021 gtattaaaca cacggactat ggcttgtttt gccatgctct catagctcgg tatcatactt
    13081 aatagaaagc tgataggcag aaacatagcg aaaatgataa aaagtatctg gctgaacaac
    13141 atcatacccg taagcaagaa tacaaatatc gtgataccca agttgaagaa caagaggaag
    13201 aacaccatac ctaaacggtt taccacctgc agtatcgtca gattgttgtt gtcgttgtcc
    13261 tcgatttctg ttttcacgac ttcctctctg gtcttgccgt cctcgtcctc tgggcttgcc
    13321 gatacgagag cttcgacacg gtctgccccg atttcctcta tacccgaatt accaaattga
    13381 agcagtagcc acggctgttg tacttgtatg gaaaataggc tatcccttat caagtccacg
    13441 ctgtccttgc ccttgctgtc gctgtcggga agcatgattt ttgttcccaa gtccagtgaa
    13501 gcggtactga tgtctgatga aaagtcattc actttcttga tgtagtcagg agcataggcg
    13561 ataaaagaag ccgataatac gaacaccaca acaaagttga taacggcgtg tagtgcctta
    13621 ctggtttccc gttttatcag tcccgtatag gcaacataga tacctacgac taagataatc
    13681 agcagaagaa atcccacata aaagcccgaa gtagaaaaac cattttgagt tacgcctgca
    13741 agggtctgta tgcttcttcc gatactgtct gccatatcgt tgataaagtc cagcttgtag
    13801 gcttcctgca ctacatagcc cgttgcattg cttagatata gtcttatcgt ccagacaaag
    13861 ttggtaatac agtaaagccc atattgcaca ctttttccaa tcccgtccag ccagttccac
    13921 ggcaaccacg cccagttatt atctgcatag aaatcaagct gataattcga cagcggatat
    13981 ttggaataaa ggttctcggt gttgatagtg tcgtccacaa gtcccgttgc gtgtgccacc
    14041 gttcccaaaa gtgaaagcag gataagggaa agtgccacga caaacagagc cattttgaga
    14101 aagcggaata tcttttttct tgtgaacaca ctttttatcc tttctttcat cactccacct
    14161 catttcgctg tatcggcggt ctggtatcaa aggcgtgcag taattcttca aagactgggt
    14221 gtatctgcac cacgcccaca cgtccgtata aatcttgaag caagcattgc ccgttttcca
    14281 aatcacgcaa tcgcttctgg ttgttctcgt cctctttgtc aatgctgaaa aattcaaggg
    14341 tctgttttat ttcgttaata tcggtgcttc taaaggcaaa tttcaaaccg atattgtttt
    14401 tcagactttc ctttgacacg tcgccagagg actgtgtaac aaaataaacg cctgcgttca
    14461 tggcacgtcc agcacgaacc agcttgttag agagcgtttc gccttgtgcc acatttaaga
    14521 acgcccatgc ttcgtcaagg tctacaatct tgaaaacact tctatccgag tggataaaat
    14581 ctaacgcaaa ggtactaatc acaatcagca tggaaacgga cagtaattca aaggtcgtgt
    14641 ccttatcggg tagcactaag tcggctactt gaatgatatt gagctggttg tctaagctga
    14701 ttgcattttg caccgtaccg tccgagaaca gcagatgtgc aaagtcgtag tccgtgaagc
    14761 tgtcgatatg gtcggcaata ttgcaagaga taggtgtatc ttcttttctt aattcctcaa
    14821 tcacatggag caatcctcgc tggtcgctct gggtaacggc acgcactgcc tttctaagta
    14881 cggggaactt ctcgccgtcc cttgaagaaa tgcccgtaag gaatgtgagt atgtcgattg
    14941 ccagactttc agcgtctttc acattctgca taatcacgaa cgggtcaaga agccctgcat
    15001 tttctctgtc gctggtaagg ttcacgatat tgatttcatg ggcgatttct gggagcgttt
    15061 ctttccagtt gccacgctcg gattttgggt ctaagattac cgcttgaccg ccaaacagca
    15121 cagagtagta gacaagcagg ttgttacaga atgattttcc accgccaaga ctttctacaa
    15181 aggcagaagc aagagcatta gtaaccgtat cttttacgcc ttgactggca agggacggtt
    15241 gtagataaac attgcgtccc gtatcgacag aatagccgat atagataccc gtgttttccc
    15301 ctaactgctg tgtcgcacca aagcccagcc cagctagaaa atcacttttg acatactgca
    15361 cataatcgtt gatgtatcgc ttgctggcag gaagaaattc agagtgaagc cccagcatat
    15421 cgccagcagg gcgtaccagc ttgacgttca aatcgtcgta gaagtctttg acttcatcac
    15481 agcgtctttt caactcgtca aggtctggag cagatacacg gataacataa gagagcttat
    15541 acatactttc tctggactgg tctaaatccg tttccagctc gtccacactg tctaatgcgt
    15601 ctaccacatt tgagctggtt tcactgccag actggtatgc atgattgtct aaatctttca
    15661 gctctttttt cttgttgcga accgtcgata acgcttttcg gttttccacg atttctacat
    15721 tcatgctggt atcaacggga aaagtaaact gctgttgctg gaaatagaag atttcactgg
    15781 acggaaaatc aagctcgccg acaatcgcat tgacagtaaa gtaggaaacg tagctttcgc
    15841 tgtcctcatg ttccaagcgt aaatgtcgct ggctttcttc cacaaggcaa cgggtcggac
    15901 gtatcaagtc ataatgcgtt atcagcgttt cctttttcag tttcttcttc ggtaagctat
    15961 actcataatc ttcataggcg acaccgtccc tgccgtagat gtgttcaatc agatagccga
    16021 agtcattttt atctaagcgt cttactttga agcgtcggct tattttattt tccaacagct
    16081 tttccatttt catgtagcgg ttgatttcat catttggcat ggaaacaaag tcattcatca
    16141 gcgtgtggtt cacttcatgg ataaactcct tgaatgtgag aaacgccgat tgcttcacgc
    16201 tctttaggtt catgctctgg tctgttacca tgagcttgaa gccaagaaaa aagcggtagt
    16261 ccacttgatt gtccccaatc atagatacta acgcttcggt ctgttcgtct atcttctgat
    16321 aggcaacgtc ttttagtcgt cccgtaacca gcttctttga ctgttcttgt atgcttcggc
    16381 ttgagctttc tgtggcaatc tgcaaagcgt gtatcttgcc ctcacgggat tgtgcgatta
    16441 gctgtcggaa gctgtcatgc acaatgaatt tctgttcagc ggatagaaaa ctgtaattgt
    16501 aaggtatcag ctcatagtag gcgaacacct cattgtcctt gttccagaca aggttgttgt
    16561 cgatatattt aatcgggaac atagctcaca ctccttactg ccgtaatagc ttcatgtagt
    16621 acctgcttat ccagtttcac ggcttttcct gcataagtaa tctttggtcg tagggcaaag
    16681 gttatctgtg atttcaaaaa gctgtacggc ttcttgccgt caaaggtctt ttgcgacatg
    16741 aaccatgtaa gagctacggg aataccgaag tattttaaaa atgccccctc aatcatggat
    16801 aagggcggta agtccccaaa cagaatgatg ataaactcgg ttatcacaaa ccatgtaatc
    16861 tgtgtaaagg taacaggaaa gggcaggtta aagtcattga ttgcatacaa gactttttcc
    16921 acgttccaga tacccgtgta gcttttaatc tttttcacgt ttttgtttca actcctttcg
    16981 tataatagaa aaggacagcc gtttttcaga ctgtccccaa tagaaaaagc tgtcagaagc
    17041 aacaatgctt gtcgctgatc ttccagcttc ttaccacggt atctcacaca taccgtatct
    17101 tgtttcaata aaagttccct caaaggataa atccctgccg tatgcttcat agtcaatata
    17161 gttctgcaaa ctagggggaa tatcgccaag tgcctgcaat tcatcaatga agtaataggc
    17221 aacgtcggtc atatcctcac agccagcgta taaaatcata tcgtccctat ggtcgtacag
    17281 ttcctccaaa cttccataat ttgatacaaa ttcgtccaaa ctgtccgtga tgtagtcggg
    17341 aagctcacat atcatttcat acatttcatt gagctcttca atcgagatat attcgccaat
    17401 ctcaatggga aagttttccg tatcatgtac ggcgtattct tcgtaccgtt cattcaagcc
    17461 gatacgctcg gcaacatctt cttcgtcaat cggaaaagag aaccagtcgc cgaccagata
    17521 cccctcattg tatttcccaa gattagcgat atatacacgc atatcctcta ccatagaaac
    17581 acctcacttc tacggcagtt catagatacc gtggtctgtt tctataaatt ctccgttatc
    17641 atcaagatac tgtccgtagg cttcataatc aaagtaacgg gtcaggcgtt cctcgatggc
    17701 agaaaaagca gggtcattgt ccaacaaatg ccttgccaca tcagccatgt ttttacacca
    17761 tgaataatgt atcacatcat ggcggtgctg gtgcagttcg tcaaggctgg taaagtaaca
    17821 catcagctcc ccgtagtcct cttgtaaatc ggcaggcaga ctttcaaagg tatggtaaag
    17881 gtcattcagt ttttcaatgg tcgcatcttc gccgacttca tcagcaaagg gcagttcctt
    17941 ttcaacgata tggtaatctt cactgtcgat aggaacgcct atctgttctt ccagttcttc
    18001 ctcgtcaatg ggaagtgtga accatgcgga acggatttct tcagaagtgt gtagtcggct
    18061 ttcgatacag acacgcattt cattcatagg ttttcacgtc ctttctttca tgcttcagct
    18121 atgctagtgt aagggacacc aaagacatag cctgcaaaat cttctaattg tttctgcgga
    18181 taatcggcaa ggttcagtcg cttcatttcc tgccacacca tacgtttatg atgtggtaaa
    18241 tctgaaatgt aggtacagcc gatacttgcc tgcatatccg aaaatatatc tttcaagcaa
    18301 tcactccaat cttaaattta ggtatgaaaa aaagcagtca atcgtataga ctaactgctt
    18361 tgtatatagc tgttaaattg agtttatcaa ttcttgtact tcattaaaaa atctggataa
    18421 atggaatcca tctgctacgg catgatgtat attcattgta agaggcatta tatatctttc
    18481 ttgctctaat tcatatttgc cccaagtaat aactggtgca agaaattttc cctcgtcaaa
    18541 aacatgaaca tcaaaatgat tatattttac ccacggtaaa caagatacat caaaaaagtt
    18601 caaagattga ttttccacaa atgcacgttc tgttttatac ttctccctat ctaatataaa
    18661 acgtttatga aattcaaata tgctatcaga aaaatctgta actatctttg tgaaattttc
    18721 atcttcttta tgaaattcag tataggacgg agaaatataa tcccacttaa ttaaattccc
    18781 attattatcc caactatatt tgaactcatc atgttcatta acaacctttg aaacagccca
    18841 tatcatagct ggataaaatt ttaaatcatg cttctttgaa aattcaataa actttgttac
    18901 atcaatatct acggttaagc tcataacaat acgcatatta tcaatgtagc tttgaaacaa
    18961 tttacctcta ttccatttat tcaaatcaat ttttgtatat ttatattcca tgcccattct
    19021 cctttacatt ttgaaatttg ataaaatgta aggctctctg gataacattt cactccatac
    19081 aagtctattc cattaagcct tatatggaga taaaacaata cacaatttca caatatcact
    19141 ccttatcaaa aaaactttcg tttattattt tcatatcttt attatatcaa ctatgtttga
    19201 gccaagcaat gaaattcatt atgctgtatt tttatctgtg taccattccg ttaccccctt
    19261 tccccttagc ccactcccaa agtgggaaag gtatgtttgc gtatccgcaa accataatga
    19321 aaaagtacgg ctatgcgccg ataatcttat tgaatagttc taagagtacg tctttgacac
    19381 cgcctgcatt gaataccaat ccaacagcaa ctaaggcaac caccaagaag ccgataagtt
    19441 ttgaaaactc acgtttaaac cctaagtaga taccaataac cacaatcgcc ataagcacta
    19501 agctctgggc gttgcttaaa aaccatgtat ataaattttg cccgaaattc atttattttt
    19561 cctcgctttc ttttaattca atcatgtgtc ggtcagcttc ctttccgaca ctcataatac
    19621 acatcagaac cacgccgata cccatgccaa gtgataccag cagtaagtcc ttaatcaatt
    19681 cccacatcat caatcactcc ttttcttttt ctatcagttc gtccaccgaa gccgtctgct
    19741 gtctgattat ctgcttgtgc ttatctgtca gctttgcctg ctgttcaatg gtcttgagat
    19801 agtccatctg attgccagcg tctatctgtt tcagcatttt caaggtcggt gcaacctgtc
    19861 tttgtaacca gttcagcgtc ctttgcagag tgtaaggctc tggctttgtc gtcagcttca
    19921 cgggcggtcg tccctcgcca atgaaccaag accagcgggc gttggttttc cagtcgcttt
    19981 ttcgcttgtt ggcttcctta tcggcaaagc ggatatactg gttgataata gaaaatgccg
    20041 tcagctctgc gtcgtagtgg gtcagcagct ctctaatggc atagtaggcg tgctcatttt
    20101 tcaaacgtat ctcaaatcgg tttttaatgg ggacttcctc aatcggtatc cctaattttg
    20161 aggattgttc ataattcttt tcatagacac agaagtacac ttcactggta aatgaaccaa
    20221 tgtaaagcgt atgtcccatg ccgtccttgt tggcttcgtt gtgctttacc agctccccag
    20281 aaccatagtt cttgaagcta cggaatttag aaatacattc ctcgttcttg catttctcta
    20341 tcagttctgg aatatccagt aagcccgttc tgtcgttgat agctaggtcg atacgcttca
    20401 tcacaccgcc atcaactaat gcgtccatga ggaagtcata ccagcttctt tcctgtgcca
    20461 gcagatagct ttcaaactga cgacagcctt ttcctttcag ttccagcagg acaccttttt
    20521 ccttgtcttg tgaagtgtaa acgaacacgt ccccgatata gtaatgctcg gtgtacttgt
    20581 aatgcccgaa atcttcgtga agcatataat ctatattcag ctttagaatg tccttgataa
    20641 cgtgctgtat atccagcgtg ggaaatcgga tacgcacata atcaaagagc aggaacatgg
    20701 gagcgtcggg attgaatttt tccaccgctt ccagtagttt gtgcttcata tcctcggtca
    20761 gtgctacctt cccagcttcg atacggctta gatgttcacg gctgatacca gccatgattg
    20821 caagccttgt ctgcgatacg ccataatcac tgcgttttgc tttcaaggtg ttcagaaaat
    20881 cagtatcatt cagttgtcat acccccaatc gtgatattgt tgtgattttg tgatattttc
    20941 aagtgattat cacaactagc taaaaactaa gaaaatcctt attcctagcg gacttttcaa
    21001 ggtttttgaa ccagtttcca gcgtaattgt gcccctctgt tagataatga ggggcttata
    21061 tctgctggcg tggctaacgc cacaccagca acggctagtc cgtgccgtcg cctttcgctt
    21121 cgcacgtcgc cgtcccgtcc tgccttacga atgcaagaga gcctatggtc tgcaaaaaat
    21181 catgtccttt cgggactaaa ggcgtgtaaa actcacttat gacacttgtt cccacatcac
    21241 aatagccacg ccccttgata cgcttctgga aaaactgttt tttcacatca gaaccaaaga
    21301 gcataccgta acccaattcg ctgatacgcc ccaatccaac acggaaattg aaattatctc
    21361 tgataccgtc cgagaaatat tttgcgtctg gacgctggca ggcaacaata aggaaatatc
    21421 cagcttgtcg tcccaacata acgattttct ttaactggct aagtaaactt acgctttcct
    21481 ttgtccccag catttcaaaa aacgccacat attcatcaaa gataagaaag cagggcggta
    21541 aaccaagata ggcgtagttt tcgcccgttt tatagtctgg gtgttgcttc atttcttcgc
    21601 ttctttgtac catgccctca taaaaggcat tgacacaatc aatcatatct tctttggtat
    21661 gatacacatt tcccataact gtacctaagt ctgcaaggtc agcgttcttt gggtctaaga
    21721 tgtaaaggac agcattcgta tgtagcagag cttcaataag cgtcagcaga aagtaggtct
    21781 taccgccacc agtcccacca gctatcagag cgtgagggag tacgtcatat tcccagacaa
    21841 gatttttcat cagcctaaga cagccgtttt ctgctttcac ttcgtcaatg gaaatacggt
    21901 tcgctatcat gtcatataaa agcgtgtact caatatagcc gtcatgcaag gtcttgtcgg
    21961 tcagctcaca gtacaaaccg ctttccagct tatcctctaa tcgcaaaagc tggtcttgat
    22021 attttcctaa tgtgatttca cagtgaatat gaagcaatcc gttttccatt tgataataaa
    22081 tctttggaaa ccagacgatt ttttcccttg atctgctttg caggtcagta aaaaaaccgc
    22141 tgtcttgtac ggtatctgct tcataccact tgttttccag tatcattcgt gccagctttt
    22201 gacggtgcag gagctttttg aaactgtcat aacagaagcg gtaatacaga aaagcgacca
    22261 atgcacaaat accagtcgct atcaatatgg ttatgaagtt gtagggggaa agcgtcaagc
    22321 cattgtccaa taagctgaaa tgttcccagt cggtacgcat gagctgtttg atattcagta
    22381 gcaggagaac cgccacaaat acaaacagaa gcgtccctat ggaaaagtgg tagacaaggt
    22441 tcttgtctct ggctctgata cggtgtcctt tattcaaaat cattcgcata aatcaatcac
    22501 tccaatctta atttaagtat gaaaaaagca gtcaatctta aaagactaac cgctttgtgt
    22561 gtatgaatat gaagttgtta cattgtaggg tatgttcatt atatatgctt tgttgtttta
    22621 actcttgatt gtgcaatttc ttcaaatagc tgtttttcgt ttaggtcttt aaaaattctt
    22681 ttgggaatta acgtatataa tcgtggtgct tgaattaagt aataaaaatc atggctttcc
    22741 catagtgcag agtaaatgtc ccacttcact tctgagtcaa tgctttgtgt tttaaattta
    22801 atgttttcct tagaaaatac cagcgtatat tcctcatgat attttgcagt ttgtttgaat
    22861 ttcagtatag gcattaggat atataaatag cttcccaatg cagttacaac aattatcaat
    22921 ccaaatatta aaatactaaa tacgctaaaa gaggagaaca gcatataaac gactgacagc
    22981 aacaaaaata cagcgactaa agcaatatca tatttatgta tagttttact agaaattaaa
    23041 tattgccttt ctgcttttat atattcactt tgagtatatt gaaatcttaa ctctactgtt
    23101 tccaaaggta ttcccccatt cgtcatataa ataatctttg ttacaatttc aaatttgaaa
    23161 atcacttttt cttgaaaagt ttcagtttta tatttctcct ttcagcaatc ttctgaaaca
    23221 cctccaccac atacaagcat tgtgccttaa atggtagtaa ggtcaattcg tcattggatt
    23281 gtatttgttt cattgcttct tgtaattctg aaagttctaa taaattgact gccacacaaa
    23341 agaaagtctt tctacgcccg tcattatagt tagaaagtaa gtaagaaaga atttgtgttt
    23401 tttcctgctg ttcaagatta tattgctcaa tgcctatgtt ttttgctctt tctaaatctg
    23461 cttttcgccg tttatgcgtg atgaaagaat cataatcatc aatgtgttga tatttttcgc
    23521 atggatattg tttgcattca tagcaatatt caatctgtcc atgttcaaga ctacattttg
    23581 caattctgca tgattgatta ccattgccac aaccgccaca gtaatttccc aaaagcatag
    23641 ggcatagtcc gcaattcaat ccgcaaagag aaaataattg atttttgcgt tcaaatcctt
    23701 tcatagtatt agtctcctaa ctttcaattt atcgcataca agcatttata aatttcatag
    23761 gtacatccat acgttctgca acttgttctg gtgtcattcc actatttaag aaacgcttgc
    23821 acactatctt catgttttct ccaacttcga taatatgttt atctgggtca taaaagcgga
    23881 ctacacgctg tccccatgaa tgttctataa tagggtggac atattcaata tcatattctt
    23941 tcagcctatc agcaaattta tcaaaatctt cttcttcaaa atagacttca aaattgttac
    24001 caccaaaaga aatatcactt gtaccgataa actctttgta tgtttcactt gtctgtaagg
    24061 ctaatccacc tgttaaagtt ttatttgccc caaaatccat aatgacataa agtccaaaaa
    24121 cctttttata aaactcaact gatttatcta tatcagttac taccaacata gggtttttta
    24181 atttcatttt tgctacctcc acaacttcca attttcttta tgtccacatg acagcatttt
    24241 catatatccg ctattataag aaactatcca tttgctaatg gtgtggtaat aaactacttt
    24301 ctatttggtt ttctttttat cctcaaaagt ttaacaaaat cgtcaaacaa agttgtatct
    24361 gttggctcaa acatcagcca ttttccgtca tggtaagttt ttgtttcatc ataaattctc
    24421 tgaacttctt ttgaataatt atctctatat gtatcgaatt ttaaccgttc atctttacct
    24481 aagataatca taaatcccac acaattttct ctagcatata aggcacataa tgttttgcca
    24541 cctcgacgat acttatattc ataattccat gctttgccac ctttattcca tagacattcc
    24601 atttcatact tttcatcaat caaggcacac aattcattcc atacactata taatgattgt
    24661 ccgaccaaag cagtcatttc ctctgcatta ggtattttat ctagcataca catttctcct
    24721 ttataagtct aaattaactg tttccacatc catattataa cagttgttta tatctcctac
    24781 aatgaaaaac tagtttgtca gcttactttt tctgctgtcc ctgcggagcg ttgttctgcg
    24841 gatttccagc ttgaccgcct ttgttcttca atacaatatc atcagctttg atgtaccaat
    24901 caaccgtagt ccctctaaag ttggcatttg ccaccgtatc agctacggga ttgattaact
    24961 ccacttccgc attataagga aagtccttta cgggaacatc agcggggatt gacacttgta
    25021 tcatgcgttc ctgcacacta catttcaaat cataagtacg acgcttaatt tcatcacttg
    25081 tcgttccgtc ctcattttct acacgcacct catgtcgaag tgcagagaat ttcaatactc
    25141 caaaagtttt ttcgttatct aatacaattc catttgttaa tctcataatc aaataccccc
    25201 ttatttgctt tctgctggta acatatcatc agccattaaa atgtagtttg taaatccacg
    25261 tcctttgacg ttgtaaccct ctgcggtaat gcgtgggtta atcagtttta ctttctgctc
    25321 tggcttaaaa tgcttctcgc cagcttttgc aggcaataca acgataatgt cgtcggctct
    25381 ctgaatatcc gaatacaagt tgtaacttct tgatacgaga gtgtaacgcc cattgatacg
    25441 ttgctggtct actttgtttt cccctgcaaa ttccaagttt ccaaaagtct gtgccacatt
    25501 cggcacgata tattttaatt ccatattatt ttacctcgtt tcttacttta agtttgattg
    25561 atgtgtgtat tctggcattt aggaaagtgc cagcaagccc ccagatagta aagggtaaat
    25621 aaatgctaac gcacccttga ctatccgtgt tcttgcaggt aatcggcaga caagccagaa
    25681 taggtatagt ctgcctatct aagctatggc ggagagcgtg atttttcttt tctcatacag
    25741 ctaccgcctt atgatttctt catcttacgg tgtttgaaaa agtatgtacc agccagccca
    25801 ccagcagaaa caaacatcat aattgcaaag gcaaggatat ttgtattgtc gcccgttttg
    25861 ggactgtctg ttttcgtagg tgtatctggt gtggttggct tctctggttc ttctggggta
    25921 ggtgtttctg gtacttcctt gatagtaact gtctgtccgt cgtcctcaat gtccttgtgt
    25981 tccgcaactt tgataggttc gtctggattg cttaaatcgt ataattcctc aaaagttaca
    26041 agctgtttac cgccaagatt ggaagcgtca aaggtaaact cgattttaac ttccatagtt
    26101 tcgctgtcag ccgtaaagat gtagtcattc tcaatacgct tgtcattgat gataagctct
    26161 gcattttctt cttttaacat ctgccagcct ttcaactgat attttgtccc tttggtaaga
    26221 ccgtctaatt taactgtatc agtgatagtt acgtctttcc cagcaagaat agtcttttcg
    26281 ccgtccttgc tggtagcagt agtatggata gtgatttctt tttcgtattc atcagtcagc
    26341 gtacctaaat caaccacaac cttatttctg gaaatgacaa tctcaaacgg tggaataagt
    26401 ttgaaacctt tgttgctttc acaacgtaat tcttcaatga tgtaagtatc ataaagcaac
    26461 gcacctttgc tgtcgtctgg ttcagaagta ccaaaccaca caccgtcctc gcttgttttt
    26521 cctgcattgg tattgtgctt gtgggaagcc caatcagaag cagtagagaa ttgtccgtta
    26581 tcatcagtta caacaacatg actttcgccc gtcgtcttgc ttgtgatcct aaacggaaca
    26641 tctgcaagac gcttgtgcga acctgcacca atttttacgc cctcaatatc gccacgttta
    26701 atctggttat agatagagtg ggcttcgtca gtcaaatcaa cgatttttcc attttctgtg
    26761 atttcaaaat caatcggctt tgcaccgtca gtcaaatatc cctctggcgg tttttgttca
    26821 gacaatctgt attttccgta aggtaatagg tcagcagaag tagaagcgat accctcaatg
    26881 tcggtatgga ttgtctttaa cacttcattt ttcttgtata acttgccctc aactaagacg
    26941 gcattctcat ttaaggaaat gatttcaaag gcggtatctt tcaaagtcgc accgccttga
    27001 gctttcgtgt ctttggtttc taaatctcgt ttctggattt tcacaccgcc acgaatgact
    27061 ttatcagaaa catggtattg attgcttcca gataatacgg caaggtcgcc gtcctctgta
    27121 atctgtgtca gatacattcc ttttatctgt tcttcgctac cgtcagcctg catatatgta
    27181 ccctctaaca agtaacccga cggacttttt gtttcctcaa cagttagtgt tcctaatgga
    27241 agtacgtttt taccgtcctg cgtatagaag ctgtcccaag atactttata tttgtcagct
    27301 aaacgagtaa tgtaatggat agcaccgtcg ctgtcttttt cagcgatagt ctttgttacc
    27361 catgttcttg taggctgtgc tggaagattg tttttgttgt aatatccagc gtagaagttc
    27421 catgtaaact ctgctccctc taaagaagcg tttccctgcg gattggattt ctgtgtttcc
    27481 atgtcaatct tgaatagctc aatcaaggta tctgttactt ttggtgtatc agatactttt
    27541 aaagtcgctg tttttccaac ttccacagat aaagagtaaa ctgttttatc aattttaaat
    27601 cctgctggtg cagaaagttc cttgatatat actatagtgg ctcttacttc aacggcttct
    27661 gtatttccgc tagtatcagt cgtaagggtg gtaagctgtt tcgtgcagtc tttatcagaa
    27721 tacacaccgt atgttgcacc agcgattgaa taaatcccgt tgccgtctgt aatattggca
    27781 ttggtggaag tcttttgaag tttggtattt ccgacagcta acttcgccca gaattgccct
    27841 aactcttgac cctcgccaga gtagatatat ccgccacagt cataacgtcc tttgttttct
    27901 ttcacaaagg cttttgctcc tgcgaatact tcatcttgta cggcttttgg gatttcatca
    27961 taggaagctc gcacattatc ccattgccag tcaggctgaa cacttaatct ctgccagaca
    28021 acaagctgtc ttaataggta ggcgtgttta ctgcttattc cgctgtggat gtctgtgtac
    28081 tgtttcacat actcaataga taaggcgacg tcagctatct ggtcggcact catacgggta
    28141 cttgcgtcag ctttggtctt atagccgttt ttaaaggctg tgttgatgtc gatacaataa
    28201 gcgtcctcac cctcaacggt taaatgtccc tcattaaagg tagaactgat agaaccgtca
    28261 ttcattactt gttctacgat actgacacgc tctttacttt ccgtccaata ctgtgtatta
    28321 gacgcatgaa ccgttgaact cggtaaagcg gtaacgacag ttgcaaaggc aagaaagcct
    28381 gtacacaatc gttttaatat ctttttcata attctaaatg ctcctttcat tttggtagta
    28441 aaatagccgt ccactaggaa cggctggaaa tagaaaagga acgctgatat tgtgcgttcc
    28501 gtagtctatg aagtattcaa tttttcttgt ttcaatactg atgtgctgta ccgtatcttt
    28561 gcatatctgg gaaataggac gtatcaaggc tcattcaatc gtagtaaatt agtagtattt
    28621 tgatgtgttt agctccttga taatgccgat agatacagtg ttttagcgga taatcaaatt
    28681 tttagtgtgt ttttctgtta atagttttct aaagatgctc tatttataaa tttttatcaa
    28741 agattttata aataattgta tttaatatac aaaatatata taaatattga tgttttatat
    28801 ataaagttgt atattttttt aaggatataa agtaaaaaaa tatacagtat caagaaaaaa
    28861 agatattggg tatttaaagt aatactttat ttaattttaa gtaaatcggg tatctacata
    28921 tatagatact aatttcaaag aataggaggg tatttatatg gaaatattcg caataggaca
    28981 ttcaaattat ccatatgata agcttattaa tatgataaaa aaatatgaca taaattgtgt
    29041 agttgacatt agagaaactc catattctaa atataatatt caatacaata aagaggcatt
    29101 taacgaatct cttagaaatt ccggatttat atatatatac atgggaaaag aatttggagc
    29161 taaaagaaat aataaagatg tatatacgca agaaggttat gcagattttg agaaagtagc
    29221 aaaagaagat atttttttaa acggaataga aagattaaaa aagggttgtc aaatgggtta
    29281 taggatagtt ttattaggag ctatgcaaga acctataaga tgtcatagaa gtattttggt
    29341 gggaaaagta ttaaataaag aaggtttcga tgtaaaatat ataatgcatg aaggaaattt
    29401 ggcatatcag gaagatatag aggaatcatt attggataag tattttagtg atagagagca
    29461 actgagtatt gacaatttat tagggagtgc attaacgaga gaagaaatga tacaagaagg
    29521 ttataagcta gctaataaag aaataggata tagaactgag aaactaggta aataaaaata
    29581 tacaagtaga taaaatacag tacttatctt aagtaaaata atattatgaa tttataatag
    29641 ctaggcatga tgtgccaatt aaaaatattc tagttattta ataatatcat taaatttagg
    29701 gtatttttta atagcacatc atgttgcagt tttaaaaaat aaaatctcta atattgccat
    29761 aatcaactgt tctattaaga gtaggatgac tagatataaa tctaactgta atttttgaat
    29821 ttaacaaaca aggatttgaa attaaaaata ctctatctcc attgacaata gaagtaatag
    29881 ctactggcaa aatatctaca aatgtatcat atctgttttt agcaatttga taaggataat
    29941 ttcctacaaa aacaaataga tttaaatcat atatattatc agtaaaccaa gcccattgac
    30001 cataaacttt gtcgatattc attgtgccta aaccaagtgt atcaaagtat gttgctatag
    30061 ttaaataaat attttccatg ttttctaaat atgaaacagt atatcttctg aaacgtatgg
    30121 gtgctgtgga agaaatagga taaaccatat ttacatttag attatttgca tttaaattaa
    30181 ccaaagtatc acatcctaaa attagtctat aaaatacaat atttaaatgg atgcgatttt
    30241 gttacatcta aagtgtaata ttttatatat tgaaaaagtg gtaaaagttt ggatgattaa
    30301 ataatattat aaaaaatata taaaatgtac ttattgttat tgctacacga tagtgataca
    30361 atattaacga aatatagcta cttttaataa taacggaaaa tatttatatt aaattaataa
    30421 atattttaaa tgtggtatcc ataaaaaata ataaacataa gataattata aagatatact
    30481 gtgttcaaat gatattaaac aagatttata ttatttgaaa gcagtatatt ataatgcgaa
    30541 caatacaatt ctaaactttg cattgtcaat ttacagttcg ataaactaat taaaaattaa
    30601 atttatataa agagggaaaa gaggaatagg gatgtttata aggaaaaatg ttataaagtt
    30661 agcaattcct ataatgatag agcagacgtt tgtcatgctt ttaggagtat ttaatacaat
    30721 aatggcaggt catattgggg aagaagctgt atctgcagtt ggaatggttg attcaataaa
    30781 caatatattt atatctgtat ttgctgcatt atctgttgga gctactgtcg ttgtagctca
    30841 acaaatagga aaaaaagata gtgaaaaggt gaatgaaact attaagcagg ctctagtgtc
    30901 tggagtaata ttatccttta caataacaat attgatgtgg gtttttagaa ctggtgtaat
    30961 taatttattt tatggttcag cagaagaatt ggtaaaatca aatgcaaaat tatacataga
    31021 gtttacatta tttacgtatc catttattgc gacacaacaa atagcaaatg gtattttaag
    31081 agggtgtgga gatgtaaaga aacctatgta tgtgactatg tttatgaata tagtaaatgt
    31141 aacattagga tatatactta tatatggtat tgatttaaat cctctaggaa taaatttgca
    31201 aacaccatcc tatggcataa caggtgcagc tatatctatt gctatagcta gaataattgg
    31261 atgtatagta attataagag ctttatttaa aggaaatgaa tttatatcta tgggtaaaat
    31321 atttccattt aagattgatg ttgaaactca aaagtctata tttaatatag ggataccagc
    31381 tggagttgaa caactacttt ttaatgcagg taaattgatt gttcaagtat ttatagttac
    31441 tatgggaaca tcagcaattg catccaatgc aataggaatg tcaattgcat ccataataaa
    31501 tgtaattggg aatgctttag ctttgtctgc tacaactttg gtgggacagt atataggacg
    31561 tggagatatt aaaggagcta agagtacttt attatattta actaaatttg caacaatttg
    31621 tttatttata gtaggagcta tatttatacc aattgcaccc tggatttcaa gtatgtatac
    31681 tcaaaatgct agtgtaattg acatctcaac acaattaatt cgaagtgatt gtttagctat
    31741 ggtaatatgg cctatatcct ttgtattatc agcagggcta aagggagccg gtgatactag
    31801 atatacaatg atgactgcag taataggtat gtggattttt agaattttta caggttacgt
    31861 attgggggtt gtattagaat ttggagtgtt aggaatttgg ataggtatgt atactgattg
    31921 gcttgttaga gggactttat attgtttaag attaagagga acaaagtggc taaaacacaa
    31981 agttgcatag aatatatgaa atcactttta gatggataac tctatttaga agtgattttt
    32041 tatgtagtta ttatcataat tataagtatg atatataagg ttattaaatt acataaataa
    32101 aggctataat agtatggata ttataaatta tatattgagc agaattacat aatttggcga
    32161 taaatattag aaatatatat ctatagaaaa taatatatat gggtatatta ttaaatataa
    32221 aaaatattag gtatttattt aataataaag gtgggtattg ttatgataaa taaaatagga
    32281 aaaataactc tctatgtaaa taatcaagag gatgcaaagt tgttttggac agaaaaattg
    32341 aactttgtag taacttatga aaaggaaatg ggtccaaata tgaaatgggt ggaagtagca
    32401 ccaagtaaaa atgaatttac aacatttgtg ttgtatgata aaaatctaat gatgaagcaa
    32461 aacaaagaga taaatgtatc tcatccatca ataattttaa gtacaagaga tattaatgga
    32521 acttatgaac aaatggcaaa taacgaggtt gaagttgggg aattaatgga gatgccatat
    32581 ggaaggatgt tttcttttaa agaccaagat ggaaatgatt atttagtcag agaggataaa
    32641 taattttaca aagtattaaa tttactcaat atctgatata attagagaca ataattatta
    32701 taaactagtc taggattaga attatataat taaaaattaa gtgtaaattt tgagtagagg
    32761 tgataaaatg tttaagaaaa tggcagtact aaaagatata gcaactaaaa taggtcgtaa
    32821 aaaagcgtat gaactattag aaatggttga aggtaatgat gcctttgtag ctgaggtaaa
    32881 gataaaaaag aatggaatag aatctaaaaa agaagaaatt atgttaaaag ataatcaaaa
    32941 aataatatta gagtatatag aaggttaaat tttaaataca tataagttga tatactaaat
    33001 ttctgagatg agtttacata aaactcatct tttttacttt tcaataactt tgttttatta
    33061 tttaatatac attttatctg cttagagttg ctgatatata aaaattactg atataataaa
    33121 agaatggata ttaatgtaat attttataga aaagaggggt attatgcttg aaataaaaaa
    33181 tctttccttt aatgttgagt ctaacaatga ggaactagga ataataaatg atgttagcct
    33241 ttcatttgag aggggaaaac ttattgttat cacaggtcca aatggtggag gaaaatctac
    33301 aattgctaag cttattatgg gaattgaaaa agctacgagt ggtcagataa ttttagatgg
    33361 agaagatata acaaatctta gtattacaga aagagcaaaa aaaggaatag gatacgcatt
    33421 tcaacaacca ccaagaataa aaggtatgac agttgaaaat ttacttacac ttgctcatgg
    33481 aaaaccattg tctactgatg tatgttgcca ataccttaca gatgttggat tgtgttcaaa
    33541 agactattta aatcgtgaag ttgataactc tctttctgga ggggaaatga aaagaattga
    33601 gatagcaact ctttttgcta gagatttaaa ggtttctata tttgatgaac ctgaagcagg
    33661 gatagacctt tggagctttg gaaaactcaa tgaaagtttt aagaaaatac atgaagagtc
    33721 taatcagact ataatcataa tttctcacca agaaagaata ttagagttag ctgatgaaat
    33781 aattgttcta caagatggtt cagtaaaaag ccatggaaca aaagaggcta tattacctga
    33841 aatcatgtgt caagttaatt caagttgtga attaatgaaa gacatgaatt aattagaaag
    33901 gaaggcaaat taaatgaaca aaatagattt aaatctttta gaaaaagttg ctgaacttcg
    33961 tggaactcca ttaggagcat acaatatacg taaaaatggg caaggagtag agagacattc
    34021 aactgaaaat gtaactataa ttcctaaaac tgataaacct ggaatagata ttatagtaaa
    34081 gccaaataca aaaggagaaa atgtacatat accagtaata gtaacagagg ctggtgtaca
    34141 ggatatggta tataatgatt ttgaaattgg agaaaatgca gatgttgtta taattgctgg
    34201 gtgtggtata cataactgtg gttgtgatga tagtgaacat aatggtatac atagattttt
    34261 cttacgtaaa ggagctcgcc taaaatatgt agaaaaacat tatggtgaag gtgatggaga
    34321 aggaaagaga attttaaatc cagttactat tgtcaatatg gatgaggatt catattgtga
    34381 aatggaaaca attcaaatta agggtgtaga ttcaactaaa agagaaatgg atgcaaacct
    34441 aggtaaagga gctaaaatag ttgtatttga gaaattatta actcatggta atcaagttgc
    34501 agaatctaat atgaaggtta tcttagaggg tgaaaactct tctgctcaag tagtttctcg
    34561 tacagttggg caagataatt ctaagcaaaa gtttaatcct tgtgttattg gggattccct
    34621 ttgttctgca catgttcaat gtgattcaat aattatggga aattctcaaa ttagtgctat
    34681 acctgaaatt gctgcaaatc atccagatgc tcttttagta catgaagcag ctattggaaa
    34741 gattgcagga gaccaaatac taaagatgat gacattaggt cttactgaag aagaagccga
    34801 gcaacaaata cttaattgct tcttaaagta aattaaagat tttatttaat ttaatataat
    34861 taatatagta taatatagtg aataagtcta aaatattttt atttttaggc ttattttctt
    34921 tatgtaagaa aagctattag agaaattata ttgtaattag gatgtggaat aaatgaaaaa
    34981 tttacttata agaaatggga caataatatc tccaacagat ggtatcaaat ttgaaaaaag
    35041 agatatcttg gttttacatg ggaaaatata tgctattgga ttgaacctta aagagaaaat
    35101 aagaaaagaa aaattactta caaataaaga gttcgagata ataaatgccg ataatatgta
    35161 tatttcccca ggatttatag atgttcacac ccattgttat aagagaaaat tacctacagg
    35221 tatggattct gattcaattg gaattgaaaa aggttctaca gttatatttg atgcaggtac
    35281 agctggtccc tcaaactact atgattttaa aaaaaagtat atggatgagt gtaaaacaga
    35341 agtatattct tttttaaatg ttacaaatga gggactaaat atattgaatg aatcaacttc
    35401 tttagatgtt ataaattttg acaaggttga gtcaattgta gaaaaaaata tagaaaagat
    35461 aaagggtata aaagtaaaag cgagtaaatt tcaatctaat gaaagtggta tagatataat
    35521 taagaaatca aagcaagttg ctaaaaaatt aaatttaccc ttagtggtat atataggaga
    35581 gtatccatca tatatagatg aagtaatgaa tattttggga aaaggagatg tggttacacc
    35641 agtatatgga aatagtacaa atggaatcct taaagaatct ggcacattaa gaaaatcagt
    35701 aataaatgca aagaatagag gagtattgtt cgatgtatgt catggagtgg accaatttga
    35761 ttttaaagtt tttaaaaaag caataaagca aggtttagag cctgacctaa taagtactga
    35821 tatgcatata aaaaacatga aagacgtaaa ctattctctt ttaaatgtta taaataaaat
    35881 tatggaactt gggatatccc tagaaaagtg tatagaaaaa gtaactgaat acccaacaaa
    35941 gattttcgat ttacatggaa ataaaggcag aataaagatt ggaggagaag gtgattttac
    36001 aatattcaca atggaggagt gtaatgatat tataaaagac tacaataata atgaacttgt
    36061 tttaaataaa aaattaagat tgcaatatac tgtaaaatca tggatgaaaa gcagtgaagt
    36121 ttatagacat ggatacgaaa atactataat aaactaaaca atagtgataa aataataaat
    36181 atatgtttaa attggtatat attggataaa tatctaagga aacaacaatt aaaaaataat
    36241 aattttaggg gaggtatttt agtatgaaag catttgttga taaggatgta tgtgtagctt
    36301 gtggagcatg tataggaaca tgtccagacg tttttagtat gagcgatgaa gggcattcag
    36361 tagcaattga aggagaaata ccagcagatt tacaagattt atgtaaagaa gccgaagaag
    36421 gatgtccagt ttcagctata acagttaaat agagctgttt aaatttattt ttaaaataaa
    36481 tatataagat ttaattgggt acttaagcta tagtattaga aatttctatt actatagctt
    36541 tttaaaatag ataaacttaa tatgtaagat attacttttt acaaatatgg aggactgaaa
    36601 tatgaaaaaa aattatgaaa tagtattatt cgatttagat ggaacactta cagaccctaa
    36661 agaaggaata acaaagtcta ttcagtattc tttaaatagc tttggcataa aagaagattt
    36721 ggaaaactta gaccaattta taggaccacc attacatgat actttcaagg agtattataa
    36781 atttgaagat aaaaaagcta aagaagctgt tgaaaagtat agagaatatt ttgctgataa
    36841 agggatattt gaaaataaaa tttatgagaa tatgaaagag atattagaaa tgctctataa
    36901 aaatggtaaa atattattag tagcaacttc taagccaaca gtttttgcag aaactatact
    36961 tagatatttt gatatagata gatattttaa atatatagca ggtagcaatc ttgatggtac
    37021 aagagtgaat aaaaatgaag ttatacaata tgtactagac ctatgtaatg taaaagataa
    37081 agataaagtt attatggttg gagatagaaa gtatgacata attggagcta aaaaaatagg
    37141 tatagattct attggagtat tgtatgggta tggttctttt gaagagctta gtgaaagtga
    37201 acctacttat attgtcgaaa atgtagagtc tataaaagat attttgttat aaatatcttt
    37261 tatagacaaa aatattacaa aatggtgtcg catatttaaa aatatgatat tatagttaag
    37321 gaagtcattt aaaaaagagg aggatgcact taaaatgaaa tctattttaa ttatgggtgg
    37381 aagcgacttc ataggttctg cacttgctaa gcgcttgatt aaatgtgggt atcaaattga
    37441 tatacttaca aatggtaaaa aggaaataga ttataatggt tttaaagaac atctaatttg
    37501 tgatagaaaa gttcgaaaag atatggaaaa cattatcaca ggaagaaaat atgattacat
    37561 atatgatatg acagcatata caaaagaaga tgtaagtaat ctgattgatt ttataagcat
    37621 ggataactta aaaaagtata tagtattgtc agcaggagca gtatataaag atagtggaag
    37681 aaatataaaa gaagaaaatg agaaaggtga aaatgaaaac tggggaaaat atgggttaaa
    37741 taaaaaagag gctgaagatt ttattataaa tagccctata ccatatataa ttattagacc
    37801 aacttacata tatggtgaaa ataataattt atatagagag tattatttct ttgaaaaaat
    37861 agaaaaaaat gaaaagatac cagtaccaaa aggaaaacaa gttagtaatc aatttatata
    37921 tattggggat ttggtaaagg tattggaaag cataatgaaa aatcctcatg taagagaggc
    37981 ctataatgtg acaaatccac agttaatttc ttgggatgac cttatatata catgtggaga
    38041 aattattggc aaagaaccta taataaaata tgtagatatg gaaaaagtag agtttagaga
    38101 aagaacgtat ttcccattta gaaatataga ctttaatctt gatataaata agcttattga
    38161 acatgggctt tatataccaa atgtgttact aaaagaaggt cttacagcaa catataaatg
    38221 gttttcagca aataagccaa aaatgcatga cagaaaaatg aacaaagttg agtctgtaat
    38281 gcaaatagtt taaaaaaata aataagtagg tagatatttt gaactcaaaa attaagtatt
    38341 ttttaaaatt ttttatctta atatttattt tgatttttat atactcagtt gcgatagagc
    38401 cgagtctatt aattgtgaaa aaatataata taagtgaaaa tggagcattg ataaaaaatg
    38461 atacaattga gagtaaatct gaaagtgtaa aagtagttca aatttcagat actcaaatag
    38521 gtagttttta ttcaactaag aatctcaaaa aagtagctaa taagattaac actttgaatc
    38581 cagatataat agtatttact ggtgatttaa ttgattactc caataaaaat ccaagtgtag
    38641 atgaaattac aactatttta tcaagtatga atgctaggtt gggaaaattt tcagtatttg
    38701 gcaatcatga ttatatgtat aaacttccta ggtattatag gcagattatg aaaaattcca
    38761 acttcaatct tttagtaaat gaaaataaaa aaataaaatt aaaagatgat aaatatatta
    38821 atatattagg tgttgatgaa atattaaatg gaaatcctaa tataaaatat ctggagagtc
    38881 agatagataa taaaaatttt aatttattgt tagcacatga accagattta gtagatatgc
    38941 ttagtaaaga tacaatgaat ttagttctat ctgggcatag tcatggtggt caaataagat
    39001 tacctattaa gggagcatta gttactcctc catatgggag gaaatatact aaagggtttt
    39061 atgatataaa tggaaatcat ttatatgtga gttcgggtct tggaagtaca aagttaccat
    39121 ttagattttt taatatacca gagataatag aatttaatat tataatctaa cataaaatat
    39181 ttagaaaata taattttgct ttttataata tgtagatgta tatactgtaa aaatggatta
    39241 aaccagtaga ttgaatgaat taatatatta aattaatata taaaatattt aagttataat
    39301 taatgtatta gacaaaataa atactattaa gaactattaa aatatagatt aaagataata
    39361 acatataata aataaaaaag taagattgtg tagattatat aaagattatt tataattaat
    39421 acaatcttgc ttttttattt aaaaatttta attattattt aaaatttttt atcttctctt
    39481 tatcccatat aaacaatttc tcagaattat ttaaagcgcc aaatacattt cttttaaaat
    39541 caggcatctc tttatttaaa ttagcaataa gattttttat gtactctctc ctagtatgac
    39601 catttgcagg gcagggattt gtgataatag gatagttaga atcttttgaa attttcttag
    39661 tcatatactc ttctatgtaa atcataggtc ttataactgt taaatcctgt ctatctaggt
    39721 atgtctttgg ggaaaaacaa tttactctac cctcataaaa catagacatt aaaaatgtct
    39781 caattgcatc atctttatga tgaccaagag ctactttatt acatccaagt tttttagcat
    39841 tatcgttcaa agcacctctt cttaaattag cacataatgc acaaggattt ttttcttgtc
    39901 ttatatcaaa tacaatttct tttatgtcag tttgaaattc ataaaaagga acatttattt
    39961 ctttacacaa tttatctagt ggagaattat caacacctcc agtatttaat gttatggcta
    40021 tcaattcaaa gttttgtgga gaaaatcttt gataactttt aagtatatga agtagagtta
    40081 aactatcttt tccaccagaa agtccaaccg caattttatc attttcttgt atcatatcaa
    40141 aatcttgtat agccttacga gctttactta gaagtttttg tatagacatt ttatcaccat
    40201 cctttaaaaa tattaaattt aagatttatt taagatttac ttataaaata cttaagtctt
    40261 atactctaaa attaacatta tagacaaaca taacaaaaag gagaagattt aattatgaaa
    40321 aaatttaaat taataggagc cattatttta gtagtattta taagtgtatt tatatctaaa
    40381 gatagattac ttaagaaaga taaagatcca atagtagctg ctcaacatga ttcagaacaa
    40441 gatgttgagg caaattctca aaataaaaat cactcaaata gtatatcaaa tatattattg
    40501 gtaaacaaga caaatggaat tagcaaaaac tatactcctg aaaatattac taaggtaaac
    40561 ataccttttg ttgaagaagc aacagaggaa gaaaaacaaa tggcaggaga acctgcaaag
    40621 gcagttgaag atttagttaa gcaagctaat tcagaaggaa tacagttttt agggtcttca
    40681 gcatacagat cttatgatac tcaactggat acttatacaa gaagggtaaa atctcaggga
    40741 cgagaaaagg cagatgcata tgtagcaaag cctggttaca gtgagcacca aactggactt
    40801 tgtattgatt taacaaatcc agaaagatgg tttgttggaa gtacaaaaga agctaaatgg
    40861 ttggcagaaa atgctcacaa gtttggattt ataataagat atcctgaagg taaagaagat
    40921 ataacaggta cagcatatga accatggcat attagatatg ttggtaagga tgctgccgag
    40981 gaaatttatt caaaaggatt aactttagaa gaatatttac aaaataaata atataaatgt
    41041 gtaaataatt tgtattatat tggaaattta gaaatgaata aatttataga ttacactaac
    41101 taaaatatag tataatttta tatgaataaa gctatataca aagattaagt taggatgtgt
    41161 aaaaatgaat aatacagttc ttgttgtgga tgatgaaaag gaaataagag accttataga
    41221 gatatatctt ttaaatagtg gatataatgt aattaaagct gaagatggaa aagaggctct
    41281 agatatttta aaaaaggaaa atattcattt aatgatattg gatataatga tgcctaaaat
    41341 ggatgggata gaagtttgta gaaaagttag agaaagtttg aatataccaa tacttatgtt
    41401 aagtgcaaaa tcagaagata tggataaaat acaagggata atgactggtg cagatgatta
    41461 tttgacaaaa ccatttaacc cacttgaact tactgtgaga gtgaaatcac tgattagaag
    41521 agcatattat tttagtggtg ctaataatga agataaagat gtcataaagg ttggagtagt
    41581 aattatagat aaggaaaaac atagtgtaac agtggctgga aatgaaataa ttttgacatc
    41641 aagagaattt gatatattat atttactagc aaataataaa ggcagagtat atagtacaga
    41701 agaaatattt gaaaaggtat ggaaagagaa atattaccaa tctaataata ctgtaatggt
    41761 tcatatgagc agaataaggg ataaaattga aaaatataca gatggagaaa aaataattca
    41821 tactgtatgg ggagtaggat ataaaattga aaaataaaag tttattaaat catatgtttc
    41881 gacccatatt agatcttata ataagctgtg ctttaacttc aatgcttatt ttaacaagta
    41941 tgtatataat aaaattatta tatttcaata gtgagatatc tgtaattaat caacttgtat
    42001 atcagttaag agatttcaga agtcttatag gagagagttt attttatcca tttttattta
    42061 caatcacatc attagcaatt tattccatga tatcgtacaa gagaaataag caaattgtag
    42121 attttataag aaagactaat agaaaaaatc aaaaattaga aatcattaaa agtgctgtaa
    42181 atttaatgga tgaaggtaac ttagaaaaaa gtatagatat tgagtatgat ttagatatat
    42241 taaaggataa agaaaaggat gatattgatg aactagcaca taaaatcaat aatatagtcc
    42301 atcaacttag aaatataact attgaagaga gacaagctca gcagacaaaa acagatttaa
    42361 taacaaatgt gtcacatgac ttaagaacac ctttgacatc cataatgggt tatttaggag
    42421 tgatagaaga aggtaagtat aaagatgaag ttcagatgat gtattatgtt gatattgcat
    42481 atgaaaaatc gaaaaattta aatgttctta taaatgattt gttcgaattg actaaaatgc
    42541 aaaataatac aataaaacta aacaaaatag aaataaattt agtagagtta ttaagtcaag
    42601 tagtatctca atttgaaatt tattttaaac aagaatttat ggttagtaga attaatttta
    42661 atgaagaaaa attaattgtg aaagctgatc caaataaatt ggtaagagca tttgaaaatc
    42721 ttataactaa tgctgtgaaa tatggaaaag atgggcatta tgtagatata gtcacagaga
    42781 aaatggaaga tatggcggtt gtaaaagtga taaattatgg agaaccaatt ccagtgttag
    42841 atttaccaaa tatatttgat agattttata gagttgaaaa atcgagaaat agaaatgttg
    42901 gaggttctgg attgggtctt gcgattacaa aaaatattgt aaatttacat gatggagaaa
    42961 ttactgtttc aagcgataaa tatcaaactg tgtttgaggt acaactgcca ataatacaat
    43021 cagcttagtt ataaaataaa agtacgatta tgtgatataa atattataac aataaagtgt
    43081 ttacaaaaat aaaaaagtga tatataattt aagtcagttt aataagatac ttatcaagaa
    43141 ttaggggaga gagttagctc agtgatccta taccaacctt ttatcaggtg gtcctgctaa
    43201 caacgatgag atgacttgaa ataatatact cttcttatca ataatagata ggaagagttt
    43261 tttttagaat taatgtaaca aactttaaag tataatggag gattaaataa tggaaaaagt
    43321 agaaagtttt aagctagacc atacaaaagt aaaagctcct tttgtaagaa agtgtagtgt
    43381 acttgatgga gtaaagggag ataaagtaac taaatttgac ttgagatttt tacagccaaa
    43441 tgtagaaagt tttggaactg ctgctatgca cggtttagag catcttttag ctacttattt
    43501 aagagataca ttagatggtg taatagactt atctccaatg ggatgtagaa caggatttta
    43561 tttaatacta tggggagatg tagatgccaa aacagttaag attggtttag aagaagcatt
    43621 aaaaaaagtt cttgaatcag ataaaatgcc agcagctaca gccatagaat gtggaaacta
    43681 cagagactta tctttatttg gggcaaagga atatgcaaaa gatgttttag ataaaggatt
    43741 ttctttaaat atatatggag aataatttaa ttggaagaga agatataagc ataaatcaaa
    43801 gtgaagtttt aagatattta caatacagag gtcaagagat agataaagac cttaaatata
    43861 ctattgatga atgtgtagct ataactaaaa ataaaataaa tcctagatat ttatctagga
    43921 tttatcctat tagaataaat aaagataatg ttgtagaatt agagggaaca aatttaacat
    43981 tagagagtaa agatgtatat gaacttttaa aagaatgtaa tgagtgtgta attatggcag
    44041 ctactatagg gatagatata gaaaaagaaa taagacgaca ctcttattca aatttaacaa
    44101 aaggactaat aattgattca tgtggaacaa cagcaataga agaagtgtgt gacattgttc
    44161 aaaataattt agaaaaggtt tttttaaacc aagataaatt tataactatg cgatatagcc
    44221 caggatatgg agatttacca atagaaaaaa atatagatat attaaacgtt ttgaatgctc
    44281 aaaaacaaat aggtctaaca attacttcta atggaattat gataccgaga aagtcagtag
    44341 tggctattat aggtatttct aatacaagaa taaataaatc taagaaagaa aagtcgtgtg
    44401 aaaattgtaa aaactataga aactgtacat atagaaaagg agcgaactct tgtggaaata
    44461 agacaatatc tgaaaaataa tatattaata tttgatggtg caatgggaac aatgcttcaa
    44521 caaaaagggt taaagttagg tgaaaatcca gaagtatttg gtcttcaaaa tccagataaa
    44581 cttatagaaa tacatacagc atacttagag gcaggttcga atgtaattct tacaaatact
    44641 tttggatgta atgaactaaa attagatagt aagtatactg tagaagaggt gattgacaat
    44701 gctgttttgg tggctagaaa agctatagaa aatgtagata atactaaacc aagatatgta
    44761 gctttagata ttggtcctat aggagaaatg ctagagccta tgggtacttt aagttttgat
    44821 aatgcatatg agatatttaa aagacaagta ctacaaggcg ttaaatctgg agttgatgta
    44881 atagtaatag agactatgat ggatttatat gaagctaaag tagctgtatt agcagcaaaa
    44941 gaaaactctg atttacctat tttctgtact atgacatttg atgaaggtgg aagaagtttt
    45001 actggatgta tgccagaatg tatggtggct actatagaag gtctaggtgt agatgcaata
    45061 ggagttaatt gttcattagg acctaaacaa cttttaccaa tagttgaaaa aatagcatca
    45121 agagctacag tccctgttat ggttcaagca aatgcaggtc ttccaaatat agttgatgga
    45181 gaggctatat atgatgttga tgcaaaagaa ttttttgaag gggttaaaaa gttcgttgaa
    45241 gttggtgcta ctataatagg tggatgttgt ggtacgaatc caagttttat aaaagaaata
    45301 tctgagaata taaattctgt tacaaaggga tgtatcgaga aaattgataa atgtgtagtc
    45361 tgttcaccat caaaatttgt ggaagtacaa tcgcctacag ttgttggaga aagattgaat
    45421 cccacaggta gaaaatctct acaagaagca ttaaaaaatg aaaatgttga ttatgctata
    45481 aatttaggct tagaacaagt aaatgctgga gcacaaatac ttggagtaaa tgttggtctt
    45541 ccagagattg atgaaaaaaa actaatgcca aaattaataa gagagattca agcagtagta
    45601 gatacacctt tacaagttga ttcttccaat gtagaggcct tagagcaagg acttagatat
    45661 tataatggta gaacaatagt aaactctgta aatggcaaag aggagtcttt agaaagtata
    45721 ttaccaatag ttaaaaagta tggttcatgt gtggttggac ttacacttga tgaaaagggg
    45781 atacctaaaa aggctgaaga aagatttgaa atagcaaaaa ggatagtcaa tagagcagtt
    45841 tcttgtggga taaaaccaaa agatatattt atagactgtt tatcattaac tgtttcagca
    45901 caacaagaag aagcaataga aactataaaa gctataacaa tggtaaagac actaggagta
    45961 aaaactatat taggtgtttc aaatatttca tttggtcttc caaataggaa agcacttaat
    46021 gcttcttttc taacattagc tttaggggca gggcttgatt tagcaattat aaatccaaat
    46081 gaatatagta tgatggaagc tatcaattct tttaaaatat taaataacac agataaagga
    46141 tgtataaact atataaatca atatagtaat ataaataatt caaaaaaatc ggattcatct
    46201 acaaagattg acaaagattt gccattggat attttagttg aaagaggatt aaaagatgaa
    46261 gcaaaaaatg taacactgaa tcttttaaaa gagaaggatg aaaattacat attagatgag
    46321 attttaattc ctgctcttga taaagtagga aaaagatatg atagcggaga tatattttta
    46381 ccacaattga ttcaatcagc agaaacggta aaagtttcat taaatacaat aaaggaaact
    46441 ttattaagta aaagtagcaa taatgtatcc aaaggaaaaa taatagttgc tacagtaaaa
    46501 ggtgatatcc atgatattgg gaaaaatata gtaaaaataa tgctagaaaa ttatggatat
    46561 gaggttatag atttaggtaa agatgtccct attgaagaag tagtggaagt tgctaaaaag
    46621 agaaatataa aattagtagg attaagtgca cttatgacta cgactgttca aagtatgaaa
    46681 gatacaattc aggcactgag agataatgag ataaatgcaa aggtatttgt aggaggtgca
    46741 gttttgacag aagaatacgc tgaagaaatg ggcgctgatt attattcaaa ggatgcaaag
    46801 tctgctgttg aaatagcaaa gttaaatttt tagcatataa attaaaataa aggttttact
    46861 aaataggata ttttatatat aatataaata taagttttag atacttatgt ttaaaacaat
    46921 aggaattaat ctataataat gagattaatt aatataaaaa atatttatca tcaacattaa
    46981 aaagggctgg gaagtctggt ataacttcca ttagcccttt ttagttaaaa tcatatgtta
    47041 aaaagcccaa ttaccatttt taaaaatctg tatttgtttt ccatcataag tctcaccaat
    47101 aatatccata tcagcagaac caatcataaa atctacatgt gttaaactgt catttacacc
    47161 atgttcatct aattcttcat cttttaaatt gtttccacct tccagacaag tcttataagc
    47221 agaaccaatt gcaaagtggc aagaagcatt ttcatcatat agagtattat aaaaaattat
    47281 atccgtattg gatattggtg agttgtatgg aacaagagca acttctccta aataatgaga
    47341 gccttcatcc gtttcaataa gtttttctag tgtatctaat cccttttcag cagagaaatc
    47401 tattatttta ccatctttaa atgttaagaa gaaattgtca attatgtttc caccataaac
    47461 aagaggtttt gtactataaa cagtcccatt tactttaaac ttatgtggca ttccaaaaat
    47521 ctcttcagtt ggaatattcg gattaaaact tattccatta gggtctttgg atgctccact
    47581 tagccaaaca tgaccctttg gcaagtctag agtcaaatca gtttttgagg atttatattt
    47641 taaagtttta aagttatttt tatttagaaa gtccatttta gatttaagat tttcattatg
    47701 ttcttcccat gcttttatag ggtcctgacc atctactctt gaacatttaa atatagcatc
    47761 ccacagtttt tctattgctt tatcttctga taaatttgga aacacttttt ttgcccaatc
    47821 ttttgttggc acagagacta tactccattt acatttatca gttagagtgt aagaacgcca
    47881 ttcttttaaa gcttttccag atgccttctg aaaatttgca actctttcag ggtcaacatc
    47941 ttttaataaa tctggatttt gggcatagac tgataaaaat gccccacctt cttttgctat
    48001 atctacatat tgttctgctg tccatttggg gaactcatga aatgcttcat ctggagcata
    48061 caagtattta ataagagtac tttcttcatc agaccactct atataaacat ttttagcacc
    48121 acatttatat gcttctttaa gtgcatttct tgcaaaatca gcacattcta ttggtgactt
    48181 tataagtaga atttgacctg gctgtatgtt aactccaact tttattgcta attcagcgta
    48241 tttttctaaa tttctattta aattcatatt tatcctccta tatttttaat attgaataac
    48301 ttataaagta ttataacatt acttatgttt ttaatattga acaacttata aaatattata
    48361 actttactta gattttgggt catattcaaa atatttatac tttatagatt gagaaataaa
    48421 aaaaatattt taattaaaac agattatgag gataacaaac ttatttaagc agtatgtttt
    48481 ttgttgataa taatattaaa gtagaaataa aaatactttt ttagtgaaaa gctatacaag
    48541 aataccgaaa aaaacttata atataataat gagatagata tttataaatg aaaaaaattt
    48601 ttctggcaaa gcttaattaa aaaggtaata gctagtgttg ttatttaaat tagcatagaa
    48661 aatcaaataa aaaaattatg ctaatgtata gacattgata aggtagaatt taagcctttt
    48721 gaatgctata ttaaactaga gtagatattc ttatgaattt caaaataggg caggaggaaa
    48781 aaggaaataa aactataaaa aatataaagt atttatataa atttatagag tttatacgtc
    48841 agaagatttc agttaggagg gcataaatgg agctttatga agccattttt tatagaaaat
    48901 ctgtaagaaa tttttccagt aagaagataa aaaagccatt gatggaagaa ataaaaagaa
    48961 gttgtaaaaa tttagaatac ttaaatgaag atttaaatat taaagcacat gttgttgata
    49021 gaggtcatat aatacatttt ttgatgggta aggaatgtaa agtaaaggca cctcattata
    49081 tagtagttac atcagacaaa ggtgaggact atttacagaa tataggattt gctacagaag
    49141 gtgtagtttt gcgccttaca acattgggaa tagctacttg ctggttggaa ggaaacttaa
    49201 agagagaaga tatcttggaa tttgtagata ttgggaataa gaattttgaa gaagatgagg
    49261 aagatgattt agattatcta gctggagtaa aaacagaaga agatgatgaa aacaaaatag
    49321 aaaatcctta tataataata gcatttggat atccagcaaa aaatgaagag ttgtttagga
    49381 cgagatatgc tagacctgat agaaagccag taaaagatat gataaataag ataaatagga
    49441 atagaaagtg gaaagatatc ttagaattga caagaagagc tccatctgta aaaaattctc
    49501 aaccgtggta tttccataag gatgaacgag gtcttcattt atttgaaaag agacctaaga
    49561 aacactgtga agatatgaat aaggttagct taggtgtagc cttaagacat tttgatatag
    49621 cttgtataaa aaataaaata gatgtttcat atgaaaaact tcctataagg aataaaatag
    49681 gaaaatcata ttttataact gtagtcgagc atgtgaaacc agaagaagaa acccaagaag
    49741 aaaatgtaac tctagaaaaa gaagaatcac aagatgaata aaattttgga aggggatatt
    49801 ggatatgtat aagtgtggaa aatgtaatct tagaggctgt tctaatggaa atatggataa
    49861 attaatgaag atatgtccaa ctagagaaat tgaactacaa caaaaagcaa agcaacttta
    49921 tgaagaagaa gagaatagaa aaatagctta taatgctgga ttagttgaag cagaggggta
    49981 ttgtcaatat actagactaa aagagattat agagtttgct aaaaagtgtg gttataaaaa
    50041 gattggcata gcattttgta ttggactaaa aagagaaatg caaacagcac aaaaaatatt
    50101 tgaacatcat gggtttgaag tattttctgt tatatgtaaa aatggggcaa tgcctaagag
    50161 tacaattgga ctagaagcat ctcaaacaat atcaaagtgt tcagatgagg taatgtgcaa
    50221 tccaatagga caagctttat ttttaaatga agctaaggtt gaccttaatg taattcttgg
    50281 attatgtgtt ggtcacgata ctttagccat gaaatatatg gaagctccta taacaacttt
    50341 agttgtcaaa gatagagtaa ctgggcataa tccagttgct gcaatatata atgcagaatc
    50401 atattttgag aaaaaattgt ttgataaaga tgaagaataa ttcaaagact tattgacata
    50461 aaaagcaatt agtggtttaa ttataaaaaa gataaaactt taaattatcc tatagataca
    50521 taaagttata taaataaaga aaaatattac agctaaattc cttaaagtag tccagagaga
    50581 ctaaagggtt atagataatg ttagtatata acctctagta aatcttctag aggtttttga
    50641 tgagtataaa ataaaaattt aaatataata aagtctttta aactagtcca gagagactgg
    50701 gaaagatatc tcatagctaa tgaatggagt tatgtataga taaaatcctt atgcctcttt
    50761 tggtgtgagg atttttttat gattatttag gctttattaa aaaggagatg taaaaatgat
    50821 aaatggtaaa gaaaaattga tagttgcaat tgatactgac gaatttgata aagctaaaga
    50881 actaatagac agattagaag atagtgtaga catatttaag gtaggtctag agcaatacgt
    50941 tgccacaaaa ggtaaaacaa tagattatct taaagaaaaa gggaaaaaaa tatttttaga
    51001 ccttaaattc catgatatac caaatactat gaaaagtgca gtgagagctg cagtgagaga
    51061 taatgtttgg ttaatgacaa tacatgtatc agatatggaa ggaatgagac aatgtgcact
    51121 aattgctagg gaagaagcag aaagattaaa tatagaaaag ccattagtag ttggagtaac
    51181 agttttaact tcattaagta accaagattt acaggacata ggatgtaata tgacaacaga
    51241 agagttagct ataaagagag ctaaactggc aaaagaatca ggcatagatg gggttgtttg
    51301 ttcagcgcaa gaagtagata aaatagtaga agcatgtgga gctgatttta taacagtttg
    51361 cccaggaata agacctaaat cagcagaggt tggagaccaa aaaagagttg taactccatc
    51421 agatgcaata aaaaaaggtg ctcattattt agttgttgga agacctataa caaaagcaga
    51481 aaatccaaga gaatcagcta ttaatattgt aagagaaata gaaaatgctt agataaaata
    51541 tttgggaggt agcttatatg aaggggaaat taattttaga agatggaaca gtatttgaag
    51601 gaaaagcatt tggatatcta aaggaagcta ttggagaagt tgtatttaat acttcaatgg
    51661 ctgggtatgg agaaatattg acagacgcaa cttattatgg acaaatagtt actatgactt
    51721 atccacttat aggaaactat ggaataaatt tagaagatgt tgaatcaaat aaggtgcaag
    51781 taaaaggact tattgtaaga gaaaaaagtg ataacccaaa taattttaga tgtgaaatgg
    51841 atatagacac atatctaaag caaaataagg taataggact tgaaggaata gatacaagag
    51901 cattaactaa aattattaga aacaatggaa ctaagagagg aattataact ttagaaaatg
    51961 tatcattaca agatgttcag tctaaattag aagagcattg taacaaagat tcagtaaaaa
    52021 atgttacaag aaaagaaatt gaaaatataa aaggtactgg agctaaagtt gtagttatag
    52081 actttggtgt taaaaatagt gtactagagt ctcttaaagc ttgtaactgt gatataacta
    52141 tagcaccagc aatgactaca gtagaagaaa ttttaaatat aaatcctgac ttaatcttat
    52201 tatctaatgg accaggaaat ccagaggata taaatgatat agttgaaaat ataaaaaaat
    52261 taataggcaa aaagccattg acaggaatag gtttaggaca tcaaatttta gcattggcat
    52321 taggaggaaa gacttcaaag cttgtatttg gacatagagg aggtaatcac ccagttaaat
    52381 gtttagaaac tggaaaggta tttataactt ctcaaaatca tggatataat gtttcagaaa
    52441 tgccagaaaa tacagaggta actcacataa atttaaatga caatactata gaaggaatga
    52501 gacataagga attaccaata tatagtgttc agtacattcc agaatacaca acaaaagaag
    52561 atttagattg tatatttaat aaattcttag cattaatata gatttagtat tatttacaga
    52621 tagtaaaaac catttagata aggagaaaaa tttatgccta aattagatag tataaagaaa
    52681 actttagtat tagggtcagg accaataata ataggtcaag ctgcagagtt tgactattca
    52741 ggaacacaag cttgccagtc tttgaaagag gaagggattg aagttgtatt aataaatagt
    52801 aatccagcca ctataatgac tgataaagaa gtggcagata aaatatatat agaaccatta
    52861 acaatagaat ttatagaaaa aataatagaa aaagaaagac cagacagttt acttgcaggt
    52921 atgggtggac aaacagggct aaacctagca gttgaacttt atgaaaaagg catactagat
    52981 aaatatggag taaagataat aggtacttca gtagaatcta tcaaaaaagg tgaagataga
    53041 gatatattta gagaagtaat gaaagaaata aatcagcctg taatagttag tgatatagtt
    53101 acagatttac aagcaggtct tgattatgca cttacaattg gttatccagt agttgtaaga
    53161 ccagcataca cactaggtgg aactggtggt ggtatagctg ataatgagga agaattaaga
    53221 gaaatacttt cacatggtct acaattaagt cctgttggac aagtattaat tgaaaagagt
    53281 ataaaaggtt ggaaagaaat agaatatgag gtaataagag attcaaaggg aaattgtata
    53341 gttgtatgta acatggaaaa tatagaccca gtcggagttc atacaggaga cagtatagtt
    53401 gttgctccaa ctcaaacttt aagtaacaaa gaatgtgcaa tgcttaaaaa agcatcttta
    53461 gatatattaa atgcagtaga agttcaaggt ggttgtaacg ttcaatttgc acttaatcca
    53521 catagttttg aatatgcagt tatagagata aatccaagag ttagtagatc atcagcttta
    53581 gcatcaaaag ctacaggata tccaatagct aaagtttcat caaaaatagc tttaggttat
    53641 actttagatg agatagaaaa tgcagtaact aaaaaaactt atgcttgttt tgaaccaact
    53701 atagattatg tggtggcaaa aataccaaaa tggccttttg ataaatttaa aaaagcaaat
    53761 agaaaattag gaactaagat gatggcaact ggtgaaatta tgagtatagg aagtaacttt
    53821 gaggctgcta ttcttaaagg gataagatca cttgaaacag gaaaatattc attagttcac
    53881 acaccatctg aggagagaag cattgaggaa ttaaagaaaa gagttgtagt acctgatgat
    53941 gagagactat ttgacttagc tgaaatgata agaagaggct ataaagtaga gatgatagaa
    54001 caaattacag gtatagataa atggtttata aataaattta aatggatagt agagcaagaa
    54061 gaaaaattaa aagttatgaa aattgaagat ttaactaaag actatcttct tgaattaaag
    54121 aaaaagggat tctctgataa aggtatatct gacttaatga agataagtcc agaaaaatta
    54181 tatgaattga gaagtctata caatatcaaa ccagcatata aaatggttga tacttgtgca
    54241 ggtgagatag atgctatatc tccttactat tattcaactt atgagcaata tgatgaggta
    54301 gttgttagtg ataagaaaaa ggtgatagta ttaggttctg gtccaataag aataggtcaa
    54361 ggtatagaat ttgactattg ttcagttcat tgtgtaaaat ctttaagaaa aatggacata
    54421 gaaactataa tcataaacaa taaccctgaa actgtaagta cagactttga tacatcagat
    54481 aagctgtatt ttgaaccatt aacagaagaa gaagttttaa gtataataga aaaagaaaag
    54541 ccagaaggtg taatactaca gtttggtggg caaacagcta taaaattggc taagttttta
    54601 catgaaaaaa atatacctat actgggaaca gattttgatg atatagatgc agcagaagat
    54661 agagaaaaat ttgatgattt actagagaga ctagatataa atagaccaaa aggaaagggt
    54721 gtatggtcac ttaacgaagg tattgaagtt gctaatgaat taggttatcc agtattagtt
    54781 agaccatctt atgtacttgg tggtcaaggt atggaaataa cttataacga agaaaaatta
    54841 tctcaatatc taca
//
LOCUS       DAEQJM010000020        54507 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.020, whole genome shotgun sequence.
ACCESSION   DAEQJM010000020 DAEQJM010000000
VERSION     DAEQJM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54507
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.020"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(348..3455)
                     /locus_tag="KRQ43_001549"
     CDS             complement(348..3455)
                     /locus_tag="KRQ43_001549"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBH2741911.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(3548..3780)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3955..4482)
                     /locus_tag="KRQ43_001550"
     CDS             complement(3955..4482)
                     /locus_tag="KRQ43_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBH2741912.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(4517..5302)
                     /locus_tag="KRQ43_001551"
     CDS             complement(4517..5302)
                     /locus_tag="KRQ43_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBH2741913.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(5312..5569)
                     /locus_tag="KRQ43_001552"
     CDS             complement(5312..5569)
                     /locus_tag="KRQ43_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBH2741914.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFNILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(5588..6046)
                     /locus_tag="KRQ43_001553"
     CDS             complement(5588..6046)
                     /locus_tag="KRQ43_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBH2741915.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(6086..6790)
                     /locus_tag="KRQ43_001554"
     CDS             complement(6086..6790)
                     /locus_tag="KRQ43_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBH2741916.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(6800..7435)
                     /locus_tag="KRQ43_001555"
     CDS             complement(6800..7435)
                     /locus_tag="KRQ43_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741917.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IPVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            7816..8856
                     /locus_tag="KRQ43_001556"
     CDS             7816..8856
                     /locus_tag="KRQ43_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2741918.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGIITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(9319..10674)
                     /locus_tag="KRQ43_001557"
     CDS             complement(9319..10674)
                     /locus_tag="KRQ43_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HBH2741919.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPISTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(10700..10969)
                     /locus_tag="KRQ43_001558"
     CDS             complement(10700..10969)
                     /locus_tag="KRQ43_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH2741920.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(11259..13199)
                     /locus_tag="KRQ43_001559"
     CDS             complement(11259..13199)
                     /locus_tag="KRQ43_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741921.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCNMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAKDSGYNIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNQLDIDVEWDFTDYYEKLEKGENFDITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKTIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNSDEKQPNTPKDD
                     VESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNPITENDDNYDLSSKSVFGTNEH
                     SFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCILTPIMI
                     GSILIVNPDTRKSIIKFIKLKK"
     gene            complement(13383..14858)
                     /gene="spoIVA"
                     /locus_tag="KRQ43_001560"
     CDS             complement(13383..14858)
                     /gene="spoIVA"
                     /locus_tag="KRQ43_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HBH2741922.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(15030..16325)
                     /locus_tag="KRQ43_001561"
     CDS             complement(15030..16325)
                     /locus_tag="KRQ43_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2741923.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNKSNENTTKVS"
     gene            complement(16509..17918)
                     /locus_tag="KRQ43_001562"
     CDS             complement(16509..17918)
                     /locus_tag="KRQ43_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH2741924.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(17970..19109)
                     /locus_tag="KRQ43_001563"
     CDS             complement(17970..19109)
                     /locus_tag="KRQ43_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH2741925.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            19428..20078
                     /locus_tag="KRQ43_001564"
     CDS             19428..20078
                     /locus_tag="KRQ43_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2741926.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSGDDELTMKMISSIEYIIKHAK"
     gene            complement(20235..21254)
                     /locus_tag="KRQ43_001565"
     CDS             complement(20235..21254)
                     /locus_tag="KRQ43_001565"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH2741927.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVINKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(21285..21899)
                     /gene="plsY"
                     /locus_tag="KRQ43_001566"
     CDS             complement(21285..21899)
                     /gene="plsY"
                     /locus_tag="KRQ43_001566"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBH2741928.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(21934..23253)
                     /gene="der"
                     /locus_tag="KRQ43_001567"
     CDS             complement(21934..23253)
                     /gene="der"
                     /locus_tag="KRQ43_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBH2741929.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(23287..24615)
                     /locus_tag="KRQ43_001568"
     CDS             complement(23287..24615)
                     /locus_tag="KRQ43_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HBH2741930.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEIGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPENILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(24853..25053)
                     /locus_tag="KRQ43_001569"
     CDS             complement(24853..25053)
                     /locus_tag="KRQ43_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741931.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(25055..25987)
                     /locus_tag="KRQ43_001570"
     CDS             complement(25055..25987)
                     /locus_tag="KRQ43_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH2741932.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNM
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(26032..26964)
                     /locus_tag="KRQ43_001571"
     CDS             complement(26032..26964)
                     /locus_tag="KRQ43_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH2741933.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYDLSFFHCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNDVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(27019..28308)
                     /locus_tag="KRQ43_001572"
     CDS             complement(27019..28308)
                     /locus_tag="KRQ43_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2741934.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(28337..29029)
                     /locus_tag="KRQ43_001573"
     CDS             complement(28337..29029)
                     /locus_tag="KRQ43_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2741935.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(29044..29805)
                     /gene="pgeF"
                     /locus_tag="KRQ43_001574"
     CDS             complement(29044..29805)
                     /gene="pgeF"
                     /locus_tag="KRQ43_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HBH2741936.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENITSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(29802..30263)
                     /gene="nrdR"
                     /locus_tag="KRQ43_001575"
     CDS             complement(29802..30263)
                     /gene="nrdR"
                     /locus_tag="KRQ43_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBH2741937.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIEEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(30285..30548)
                     /locus_tag="KRQ43_001576"
     CDS             complement(30285..30548)
                     /locus_tag="KRQ43_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH2741938.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(30652..31425)
                     /gene="sigG"
                     /locus_tag="KRQ43_001577"
     CDS             complement(30652..31425)
                     /gene="sigG"
                     /locus_tag="KRQ43_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HBH2741939.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(31517..32239)
                     /gene="sigE"
                     /locus_tag="KRQ43_001578"
     CDS             complement(31517..32239)
                     /gene="sigE"
                     /locus_tag="KRQ43_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HBH2741940.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(32264..33136)
                     /locus_tag="KRQ43_001579"
     CDS             complement(32264..33136)
                     /locus_tag="KRQ43_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HBH2741941.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGSAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(33427..34701)
                     /locus_tag="KRQ43_001580"
     CDS             complement(33427..34701)
                     /locus_tag="KRQ43_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH2741942.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(34985..36142)
                     /gene="ftsZ"
                     /locus_tag="KRQ43_001581"
     CDS             complement(34985..36142)
                     /gene="ftsZ"
                     /locus_tag="KRQ43_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBH2741943.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(36332..36685)
                     /locus_tag="KRQ43_001582"
     CDS             complement(36332..36685)
                     /locus_tag="KRQ43_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HBH2741944.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(36784..37458)
                     /locus_tag="KRQ43_001583"
     CDS             complement(36784..37458)
                     /locus_tag="KRQ43_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH2741945.1"
                     /translation="MKKKIVILGAFILGIFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(37463..38161)
                     /locus_tag="KRQ43_001584"
     CDS             complement(37463..38161)
                     /locus_tag="KRQ43_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH2741946.1"
                     /translation="MKKRFINKSIIIGSVVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKTEKENLQSEVNSVKKDIETYRGKNNKGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVFNTYMY
                     LKEDKLCMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(38184..38924)
                     /locus_tag="KRQ43_001585"
     CDS             complement(38184..38924)
                     /locus_tag="KRQ43_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HBH2741947.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNINLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSVDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(39194..40420)
                     /gene="murG"
                     /locus_tag="KRQ43_001586"
     CDS             complement(39194..40420)
                     /gene="murG"
                     /locus_tag="KRQ43_001586"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH2741948.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(40438..41568)
                     /gene="spoVE"
                     /locus_tag="KRQ43_001587"
     CDS             complement(40438..41568)
                     /gene="spoVE"
                     /locus_tag="KRQ43_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HBH2741949.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(41620..42975)
                     /locus_tag="KRQ43_001588"
     CDS             complement(41620..42975)
                     /locus_tag="KRQ43_001588"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBH2741950.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEVVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVTKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(42994..43962)
                     /locus_tag="KRQ43_001589"
     CDS             complement(42994..43962)
                     /locus_tag="KRQ43_001589"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBH2741951.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(44003..45376)
                     /locus_tag="KRQ43_001590"
     CDS             complement(44003..45376)
                     /locus_tag="KRQ43_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBH2741952.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREASAQNAFVA
                     IVGENLDGHTFMKPAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDIYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(45543..47522)
                     /locus_tag="KRQ43_001591"
     CDS             complement(45543..47522)
                     /locus_tag="KRQ43_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HBH2741953.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(47534..47881)
                     /locus_tag="KRQ43_001592"
     CDS             complement(47534..47881)
                     /locus_tag="KRQ43_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741954.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIAIFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(48367..49302)
                     /gene="rsmH"
                     /locus_tag="KRQ43_001593"
     CDS             complement(48367..49302)
                     /gene="rsmH"
                     /locus_tag="KRQ43_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBH2741955.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGKLVDIIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNKGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(49332..50078)
                     /locus_tag="KRQ43_001594"
     CDS             complement(49332..50078)
                     /locus_tag="KRQ43_001594"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBH2741956.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKDDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKHNISEE"
     gene            complement(50475..51761)
                     /locus_tag="KRQ43_001595"
     CDS             complement(50475..51761)
                     /locus_tag="KRQ43_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH2741957.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(51776..53041)
                     /locus_tag="KRQ43_001596"
     CDS             complement(51776..53041)
                     /locus_tag="KRQ43_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH2741958.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            53357..54454
                     /gene="ychF"
                     /locus_tag="KRQ43_001597"
     CDS             53357..54454
                     /gene="ychF"
                     /locus_tag="KRQ43_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBH2741959.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        16902 a         9979 c         5784 g        21842 t
ORIGIN      
        1 tgtgcgtagc tattttttaa tcaatactta actttttgtt ttcaccatac atcaaaacgc
       61 acccctttgc ataataaata aaccaccctg cagaacacac gataaattta taaataaatt
      121 tatcagaagt agcttactaa aaatattatt catcctcact taaacgttta ttcattaata
      181 ttctatcaca tgacataaat aatttatatg atttatatag atttatttat tgtaaatttt
      241 ggaatattaa aacattttat tgaatagata attatattac ataaaaaatc cctatagaaa
      301 tctataaact aatttctata gggattttgg ttaactaact attcttttta tttttttata
      361 acttttatac ctgtcatatg gtcatttaag ttttgttcct ctaaagattt atcatctact
      421 ctgtttattt ctaaagctaa agtttcagac ttgatatatt cattaaaatg gtcaacagcc
      481 ttagcaattt catcatcacc acagtattct attactatat tatctaatac ttcaaagtta
      541 ttagattttc ttaattgctg tactttagat ataaattctc tagcataacc ttcattaatc
      601 aactcttcag ttagcttagt atctagtata acaaaaagat tgttttcaac agatacatta
      661 aatccttcct tagcagttat acctattaat actaaatcct tattaaattc aaaagcttcg
      721 ccatctaaat caactgttaa agtctcacct ttttcaagtt tattagcagt ttcatgagca
      781 tttaatttac ttaatgctcc aacgaataaa ttcatcttag aacctaataa tggccctgct
      841 tccttaaagt ttggttttaa actaaagttc atatactcat ctaaatcctt agcaaatatt
      901 acctctttaa cattaagctc ttcttttatt aaatcaacta catcacttat tgtatcttca
      961 aacttaccat ctactaacac tttttgtaat ggttgacgaa cttttattct ttctacttct
     1021 cttgaagctc tacctaaagt aactaagttt ttagctaaat ccattttttc ttctaattta
     1081 gtatctacta actcttcatt acatttagga tattcagcta aatgaacaga tacttctcct
     1141 gttaagtttc tatacatttc ttctgacata tatggtgcaa atggagctat agctctacaa
     1201 agaccatgta acaattcata agttgtattg tacactgctt ttttatcttc tgttaattca
     1261 gttgcccaga atcttcttct tgaacgtctt atataccagt tagataaatc atcatttata
     1321 aaatcttgta tcatccttaa agttttattt aactcaaata tagctaaatt ttcttctaca
     1381 tctttcatta aattattgaa cttagataat atccatctat caagttctgg tctatcttta
     1441 tattctacaa aaaattcagt tggatttata tcatctgtgt ttgcatataa agtaaagaag
     1501 ttatatacat tcttcatagt acctataaat ttactttgga tttcttttaa tccatccata
     1561 tcaaatttag ttggagtcca tggtggagaa acatatagta aataccatct taatgcatct
     1621 gctccatatt ggtcaaacaa ttccattgga tttactgtat ttcctcttga tttactcatt
     1681 ttcttaccat ctttatcaag tacaaggtct ggaactaaaa cactcttata tggtgctttt
     1741 cctaatacaa atgttgatac tgcaagtaat gagtagaacc aacctctagt ctggtctata
     1801 ccttctgata tatagtcagc tgggaacaat tggtcaaaat tttccttatt ttcaaatgga
     1861 tagtggtgtt gagcaaatgg catagcccca ctatcaaacc aacagtctat aacctctgtt
     1921 actcttgtca ttggttttcc acatttttca cattttaagt gtatatcatc tacatatggt
     1981 ctatgaagtt caactgtttc tggatttaca tcttctatag ctttttcagc taattcagct
     2041 cttgaaccaa ctgaatctgt atgaccacat tcacatctcc atataggaag tggagttccc
     2101 caatatctag ttcttgatat tgcccagtca tttagatttt ctaaccagtt tccaaatctc
     2161 ttctctccta caaaacttgg gaaccatttt acaccattat tattttctat taatttatct
     2221 ttaagtttag tcatctctat ataccagctt ggttttgcat agtatactaa tggagtttga
     2281 catctccagc agtgtgggta attatgaact actttttctt tgctatataa tttattttca
     2341 gaagctagcc attttattat ttcaacatct agcccatctt ccattacaaa tctaccttcc
     2401 caaggagtag atgtaaattt accagtttca tctactggtt gaataactgg taaatcatat
     2461 cttttacctg tgttgtagtc atcttcacca aatgctggtg ctgtatgaac tataccagtt
     2521 ccatcttcag tagttacata atctcctact gtaataaaaa atgctttttt gtcaacttct
     2581 acaaaaggca ttaattgttc atattctaaa ccttctaggt ctttaccttt catttcttct
     2641 aaaacttcat aatcttcacc tagtacttta tcagctaaag gtttagatac ataatatacc
     2701 tcatcacctt ttttaacttt taaataatct acatcagcat ttactgttaa tgaaacattt
     2761 gatggtaaag tccatggagt tgttgtccat gctaagaagt attcatcagc atcttttttc
     2821 ttaaatttag ctataactgt attagttttt acttctttat atccttgtgc aacctcatga
     2881 ctagcaagac cagttccaca tcttgggcaa taaggaagta ttttatgccc ttcatatata
     2941 tatccttctt tgttgaattt gtttagtatc caccatacag actctatata gttattatct
     3001 aaagttatat atggattatc taaatcaact tcataagcca ttctctcagt cattattctc
     3061 cattgttttt caaatgagaa aactgactct ctacattttt ggttaaattc agctattcca
     3121 tattcttcta tttgttgctt gctagtaaga cctaactctt tctctacttg tatttcaact
     3181 ggtaatccat gtgtatccca accagctttt ctctttactt gataaccaga cattgtttta
     3241 tatctacaaa ctgaatcttt aagcgttcta gataaaacat ggtgtactcc aggatttcca
     3301 ttagctgttg gaggtccttc atagaatacg aaacttgggt catctttccc tttttctaaa
     3361 gttttttcaa gtatatttat gtctttccaa taatcaaaaa cttgtgcttc tgcttgtttt
     3421 acagaactgt ctaccaatgg cttaaatttc gccatgtaaa tcaccctttc ctactaaata
     3481 ttataattcc aaaatttttt attctttcac ataaatttaa atactaaaaa actcgccccc
     3541 tttaaaccaa agggacgagt tataaatcgc gttaccaccc taattctata tgtaaactaa
     3601 atactagcta catataacac tctaatagta taacggtact aaccggcaca gcttagtaga
     3661 atttaatcgt tcagcctgca gctcaagagt gatttttatc tttataaatt cattggttct
     3721 cagcataccc aattctctgt aaaattatct aaagataaat gtctctatca acgcttttaa
     3781 aaatttatct gtgtttatat gaaattttat aacaaataat ttgaatagtc aatatatttt
     3841 tgaaaaatat aataatttct atttttctta catttttatc ctatttttaa tctttgttat
     3901 agatttctca aactcacaca gttattctac ataaaaaata aacaaattac aagcttattc
     3961 taaagttgta gcagcttcat cattactata attatacact gttgttcctt caaatgcatt
     4021 tacacatttt tcatctacat cataaaaaat ctcatcaaca cttcttattt catcttctaa
     4081 cagtgattta aatttatttc taaatatctt aaattctttg actaaagcat catactcttt
     4141 tcttatctct atgacacggt tattagcttg ttctataatt tgtctagctt ttaaatcagc
     4201 ttcttcaaca attatcttag cctttttatt agccgcgcta caagtgtctt ctgctgcact
     4261 ttgagcagtt attaaagtag cttttagtgt ttcttcaata ttttcatact tgtttacttg
     4321 gtcttgatat aaccctaatt tttctttaag agctgtattt tccctacata gagattcata
     4381 atcttccttg atgatatcta aaaattcatc aacctcttca tctctatacc ctcttaaacc
     4441 ttttttaaac tctttatttt ctatctcaat tggagttagc attacatttc ctcccagcta
     4501 taatttaaat tagtccttat acaattaatc ttgcttgaac ttttattttt ccttttttgg
     4561 taatatctcc tatttgtgtt accttagctc ttcctttgcc tctaatagaa atcaaatcat
     4621 cattttttac tattttagaa gttgaagtta tcttttcata attgacatgg actttttctc
     4681 catttatgta ttttgcacta tcttgtctag atatattgta aataccactt atcacacaat
     4741 ctaacctatc tgaagatact gtaaatgata cttctttata ttttgaagaa ctattaacaa
     4801 tattttctct ggaaatttcc tttacaatta cattatttct tgaaaccttt tctaagttta
     4861 caattataaa atcgcaaata tcactactta caactacttg acaaaagcta tcatgtataa
     4921 ttatatctcc aattttttct ctttttatac ctagacccag tattgaccct aagtaatctt
     4981 tatgagatat atttttaaac ttgaaattcc cttctatttg taaaaatcta agagtatctt
     5041 ctatatcttc atattccatg taaaatggat aaataaatac agtgcttctt tcagcttgtt
     5101 cataacctcc atccacactg tattttattt catttgtaga atttaatatt gctacagcat
     5161 ttttcacttc atatggatta agaaactccg tagacttaac atcatagttt tttatacaac
     5221 tattagcctt gtctatcact ttaaacattt tatttttcaa gtctatatcc tttatgtgat
     5281 ttgttagttt taatttatcc atcctatcac cttagaatat aaccaatact aattgtctta
     5341 ggaacatcaa taatactatt gcaattaaag gagaaaaatc tataggtcca tttgtatatt
     5401 tatacattat agaccttatt ggcccttcta ttggctctgt aagattttcc aaaatattaa
     5461 aaattttact ttgtcttcca tttggaaacc aagtcatcaa gctttttata actatcatcc
     5521 atgctattat atctaaaaga taataaagtg caattcttat tgttcccata tattaaccgc
     5581 ctttttacta tttattttgc caagggaaga atgctttact ttctaattct tttttcatat
     5641 ttgcatctat atccacatta ttaggagcta gtataaatat tgatttagaa accttttgta
     5701 tacttccatc taatacataa actgccccat tcataaagtt aaatatagat ttacgaactt
     5761 cagaattagt caatccttcc aaattcacta taactgccct tctttgtttt agatggtctg
     5821 ctatagttgc agcttcatca taaaccttag gttcaactat tacaactttc atttggctag
     5881 ttgtatgtaa atttacaatt ttatttgctt ttgcagtact aaagccactg ttcatttctt
     5941 cttcttgaac tatatcgtcc atgccacttt catattcatc ttcaatataa tcttcttctt
     6001 catcaactat ccaattctta aatttagata ttattccatt tgacattatt aacttcctcc
     6061 ttaaaattta ttcaaatttg agtaattatt ttttattgta gtttctttct ccaaagattg
     6121 atgttccaac tctaacaatg gtagcccctt cctctatagc aatttcataa tcgtgactca
     6181 ttcccattga caaaacatcc atccctacat tagggatgtt tagttctttt atttgttttg
     6241 ataaatcttt aagaccttta aatacacctc ttatctcatc ttcatcttct ataaaaggtg
     6301 ccattgtcat tagacccttt atttttatat ttttatattt ttctgacact tctttgacaa
     6361 aatctacaac ttcttctcta tcaagtccat gcttagactc ttctttagat atattcactt
     6421 gtactaagca atctatttct ctgtttattt gttctgcacg tttttgaatt tcttcgcata
     6481 atgcaattct atctaaagag tgtatcatac aaactttatc gattatgtac ttaactttat
     6541 tggtttgcaa agttcctatc aggtgccagt ttaatttgtc acctataata tcatactttc
     6601 tagctaattc ttggggttta ttttcaccaa cagaagtgat tccttccctc attgcctcat
     6661 taactaagtc tacatcaaca gtctttgtga ctgccaaaag ggtaatctct ttgctgtctc
     6721 tatctacttt ttttgcagct ttatcaattt tgtttcttat ctcagacaaa ttatctttaa
     6781 tagaacccat tattatcacc tactttatcc ttatatttgt gtttatactg ttaggtctta
     6841 aaattatttt gtcatataga ttaacacttg taactccatt tatgtcattt ttataataat
     6901 ccacaaatac agaagattca ttctcataag ttattccttc taatatgaca aattttacac
     6961 tttgtgattg ttcatcaatt acatatacac cacgtttatt gtcttttgtt tttatagaag
     7021 ttttaggtat ttttaaacat tccatctgat tatatattat atcaaattct tcgacacttg
     7081 tatcctgatt tgcaacaatt tggttactta tttttaattt taccattatt ttattattat
     7141 tttcatatat tttgtaaact tttgcatcta atttttgctc atgatattca attattacat
     7201 tttgattttt ttcaaagtta ttagaatctt ctttactgat gtatgtagat agataattac
     7261 tttggtcatt ggcatctttt tctatagttc cttttacagg aatctttgca tcaacttttt
     7321 cattttttaa caccaacgta tctacatttt tgctaattat cattactaat atattaaata
     7381 ctaaatatat aagaatacca agtatcacta atctggtata ttttaccttt ttcaaagact
     7441 ctccccctat aaaattactt tcattataag tacttcttct aaaaaatgtt tattcctttt
     7501 ttataagcta atattttacg ttctaataat tattttttcc atattaaatt tattttttat
     7561 caatcttcct atacaagact gcattattta tatataattg tattataaag tataagttta
     7621 atttacattt tatacattaa gcttacttta tatgttttta tagttatttt tatttttaga
     7681 tgcaatataa aaccaattaa gatttaaaat aacttttgtt atgttgacat ttatttaggt
     7741 aatcatttac gaatcgggat aacgttatca taacaaaagt ttatgtccta aaaaaaatac
     7801 aaggaggatt ttcttatgtc agaaatttta ttaggaacag gtttactttt attggttcta
     7861 tgttgtttca caatttttag ttacaaggcc ccatatggta tgaaggctat gggagctcta
     7921 gcaaacgctg catgtgctac tttcttagta gaggcattca acctttcttt acttggtgat
     7981 gttttaggta tggaattttt tagaagtgtt ggagctgcta atggtagtct tggtggagtt
     8041 gctgctgcta tacttgtgcc tttagcctta ggtgtatctc cagtttatgc agttttaata
     8101 ggattatctt gtttagattt ttctatatta tctggattcg ttgctggata ctttgtttct
     8161 ttcttaatta agtttataga gaaaaaagtg ccacctggag tggatttagt ggttgtaatt
     8221 cttctatgtg caccgctatc tcgtcttata gcatcaaatg tagacccatt agttaatagt
     8281 acactactac aaattggaca agttttgata gaagctacca acattagccc tataataatg
     8341 ggaattatac taggaggcat aataacagta gttggaacgt ctccacttag ttcaatggct
     8401 cttacatcta taattggtct tactggtctt cctatggcaa taggagcatt aggtgctttt
     8461 ggttcagctt ttatgaactc aacactattt gcaaaattga aattaggttc taaaaaagat
     8521 attatatctg ttgctattga accattaacc caatcagaca taatttcagc taatccaata
     8581 cctatatatt ctactaattt ctttggagga gccttttctg gtatcattgt agccttgatg
     8641 ggtcttgtaa acatgacacc aggtacagct acacctgtgg ctggttttgc tataatgttt
     8701 gcttataatc cagttcaaca agttcttata acagctggtt tatgtgcttt attcaatgta
     8761 attgcaggat ttttaggttc aaaaatattc agtaccttta aagttcttac tgctggtgaa
     8821 atacgtggta ctgatgtaga agaagaaatt gcttaaaaaa caataagatt tataaattta
     8881 tatctcaagt agtagagttt tatattgtag gcaattttat taattgcaaa cgttttattt
     8941 tttatttatg tttatgatta ttatgtgtgt tgaatattta gataaatttt tatttattat
     9001 ttttatttag atttttgttt agttttttat ttggttgata tattaggaat aaaaattagt
     9061 atagtttatt attagttaga tagcataact ttttagatac ataaaaaatt ttatattaat
     9121 tagatattat taaaataaaa gcgatacatg aatttttaaa tgtccatgta tcgctttatt
     9181 tttgccataa tcttaacaac tgatttttaa agtttattat cttaacgaag ttcattatct
     9241 tatataatat ttaaatgcat agacttcttt aatttaacca tctaaatatt taattaaata
     9301 ttattatatg taatataact aatttttaaa tgaatgtata ggagctggaa tccttcctcc
     9361 tctttgagta aataattcag atgaatttgt acttataggc attactggtg ctcgtcctaa
     9421 aagtcctcca aattctacca tatcacctac atcacatcct ggggctggta taattctaac
     9481 ggctgtagtc ttattattaa tcatacctat tgctgcctca tcagctatca tagctccaag
     9541 cgtacctgct gtagtatttc ctggcacagc tatcatatca agacctacag aacaaatagc
     9601 agtcattgct tcaagcttat ctatacttaa agcaccttta ataacagcat caatcatacc
     9661 tgcatcttca gatactggta taaacgctcc actaagtcct ccaacatgtg aacatgccat
     9721 tactccacct tttttaacag catcatttaa aagtgctaat gctgctgtag tcccatgagt
     9781 accaacaact tcaagaccca tttcctctaa tatatttgct actgaatcac caatagcagg
     9841 tgtaggagct agtgataagt ctattatccc aaatggaaca tccaatctac tagaagcttc
     9901 ctttgccaca agttgtccaa ctcttgtaat tttaaatgca gtctttttaa ctgtttctga
     9961 aacaacatca aaaggctctc cctttacttt ctctaaagct ctcttaacaa caccagggcc
    10021 acttacacca acatttataa ttctatcagc ctcaccaaca ccatggaaag ctcctgccat
    10081 aaatggatta tcttctactg cattacaaaa tactactaat tttgcacaac caaaaccttt
    10141 tgcatctttt gttaattctg cagtttcttt tatgatttct cccatttctt tcactgcatc
    10201 catatttata ccacatcttg tagaacctac atttactgaa gcacatactt tattagtact
    10261 tgctagagct tttggaattg acttaattag tatcttatca ccttttgtat atcccttttg
    10321 aactaatgct gagaatccac caataaaatc tatacctaaa tcctctgcag ccttatccaa
    10381 tgtctgtgca aactttacat agtcattttc atctgttgca cctgcaataa tggaaattgg
    10441 agttactgat acccttttat ttacaattgg gataccaaat tcacgctcta tatcttttcc
    10501 aaccttcacc aaatctttag cagaactcat aatcttattg tatatttttt ctctagcttt
    10561 atctccatca gggtctatac aatctaataa agaaatcccc atagttatag ttcttatatc
    10621 caactgttct tcatctatca tctttattgt ttcaagtata tttcctacat tcactattat
    10681 cacctcccct tactgtctac tacagattat gcattgaatt aaatatttct tctcgctgaa
    10741 tttttacatc cactgataat ttcttacctc tttcaaccaa gtcctcaacc gttttctcaa
    10801 aagaatttaa tgatttctct aaatcaacta tcataatcat agtaaaataa tcctgtaata
    10861 ttttttgtga tatatctact atgttgatat tttgcttgta taattcatca ctaattcctg
    10921 ccactatacc tggtttatcc tttccaatta ctgttaaaat tgctttcata ataatatcct
    10981 cccttatttt tttataaatc ttatattttt acaaattgaa ctatgtatta acatatattt
    11041 catttatttg ttagtaaacc actttttatg tatatattta atatatttta atacctatac
    11101 attcatttgt caattttttt tcaatattcc attattttta tactatttag aaaattcata
    11161 ttttatatat gttttctcaa caataaatac agttttcata ataatgaaag gtattactta
    11221 gcaatctcgt gattttctaa ataatacctc tctaaaaatt atttttttaa ttttatgaat
    11281 ttaattatac tttttctagt atcaggattt acaattaata tagaaccaat cataattggt
    11341 gttagtatac aaaataaaaa aataatatct ttttttagat tatattcttt agattctaat
    11401 ttataattat tatttattat tccatcataa tcacttatat ttgacttatt tttatttgta
    11461 tcttgatttt tgttagaaat actttcccta taaggaaaag aatgttcatt ggtaccaaat
    11521 actgattttg agcttaaatc ataattatca tcattttctg taattggatt tttattgtaa
    11581 aatccttttt ctttatcaga attattttct ttattaccgt ctttaggtat atcatgagga
    11641 tttttatttt cattgctatc agtacttgat tctacatcat ctttaggagt atttggttgt
    11701 ttctcatcag aattattatt ttcattatta ttgttttgat tgttattact atcattattt
    11761 tcatttccat tattcccatc ttgattgtta tcatcctcat ctctatccgg gtcgtctcta
    11821 cctcctcctc cacggtcacc atcaatatca tcattttccc gttcatcatc tggcgtctct
    11881 tggttgtctc cgcctcccat tataaatcct ggtttaaaaa ctatatttga atacccttct
    11941 tttaatcctc ctaccacttt tactctaaaa caacgcaact taaaatcttc aaaaaaaagt
    12001 atagcttgat ctctaatatc ctcctgttct tcagatatcc aattgattcc atcgcttgaa
    12061 tattcaacaa aaaccttact tgcactatac ggcatatcat aaaataaaac agctacatat
    12121 ccattttttg tattttgaaa ttccagttcc aaattgtcta ttgttttttt ctctataaca
    12181 gatacattca aaataggaac tacatcatca tttattataa ttttttcttt atttaacatt
    12241 tctgttttaa actttcctgt tatatcaaaa ttttctccct tttccaactt ttcataataa
    12301 tcagtaaaat cccattctac atctatatca agttgattac cactagatgt ttctaatacc
    12361 atatatttgg gaaattttat attttctatt ttatcatctt tacttacttt tatttcatca
    12421 ctaaatacac caattcccct atgacaacat ttcacaatat tatagccaga atctttagct
    12481 atagagggta taagctcatt ataatcatca attatataaa ctttcttact ttctgatata
    12541 attgattgtg ccaacttatt attatctctt agtaacccac tttcattgtt gctactatat
    12601 gcttttattg aagtttcttc tatctcaaca tcacctttag aataaacacc tatagcatgt
    12661 tctccattca cttcaatatc cttatttagt attctaatat cattttcagt ataaattcct
    12721 attgcatctt ttccatttgc ctttattttt tcaacagatt cgtaggatga tttaatatgt
    12781 aagtctcctc cttcttcaac gtataaggct gtcccatcag tagcaattat gttgtttata
    12841 ccaatactta tacttccacc attttctata tgtattactc cttcttttcc tccttcacct
    12901 attatattca attcattatc atcaataata aatctcccat gattttttat caatatttta
    12961 tatttgttgg tatctattgt aaaattactg tcataaggaa tataaaatct aaactcttca
    13021 tctattacca tattacaaga aagagtataa actatttctt ctttattatt tttattttct
    13081 tgaacccacc tttcaaaatc ttcaagacaa ttttcctctt gtccaaaaac tttatgtgga
    13141 aaacttataa aacacaaaac tattatactc ataaaaataa atatctcata ctttttcatc
    13201 ttacactcct agaaattttt tagctttgaa acaatcctgt cgaaacatat acttcaccca
    13261 ctataatttt tccacaatta tcaattattg tcaatttata taagtatctt tattaattgt
    13321 tataaataaa aagctactta ctaaagtaaa cagacgtttc actttaataa gtagctatat
    13381 ttttataaca aaatagttat aatattagaa cttccttcat ttacaatttt ttgtaaagtc
    13441 ttttgcattt taactcttat ctcttctggc atagtatata atttactttg taattgctct
    13501 tttactaagt catgtagtga cttaccaaac atatttgatt cccataaatc tgctggttgc
    13561 tcttcaaata cttccataag atattttatc atctcttcac cttgattttg atttccaact
    13621 attggagaga cctctgtaga tatatctgct tttataatat gaagtgatgg tgcattggct
    13681 tttaacttga taccatattg ttttccttgt ttcattattt ctggttcttc cagactaagt
    13741 tcttctaaag aaggagctac tactccatat ccttttatct tggcatctat taaagcactt
    13801 tctattttat catactcatt tttaacttta gatagtctag ttatcagact aagcagttga
    13861 taatctcctt caattttaaa tccacttttt tcttcaagga cattatagaa taaatcttgc
    13921 tttgtctgta aatcaatatt tataacacct tctcctagct ctacattatc aacacctgta
    13981 tcttccaaaa actctaactc agaaaatcct tgtataatac cttctatatc tcttatttta
    14041 cctatatcta taatactttg ttttaatgtt gttattatgc tactttttat ccaatgattt
    14101 ctttcaagac cttcaaccca ttttggtaag ttgattctta tttctgtaag tggaaaatca
    14161 tataatacag cttccataac ctcctctata tcttcttctt ccatttcaac cacattcatt
    14221 ggaagaactg gaacttcata cttttcttcc aattcacttc taagcatact cgtttcctca
    14281 ctttttggac ttaacgtatt taaaaccact gcaaatggtt ttttaagatt tttcaattct
    14341 tgtataactc tctcttctgg ttctacatag ctttttctgt caattccagt aactgaacca
    14401 tctgtcaaga caactatccc tattgtagaa tggtctttta taactttttt agttcctatc
    14461 tctgctgcct tttcaaatgt catagcttct tgtgaccaag gagtggatac taatctttgt
    14521 tttccacctt cctcatgccc taaagctcct tcaactatgt atccaacaca atctaccatt
    14581 cttactttta aagatactgt gtcttttatt tttatttcta caccatctgc tggtacaaat
    14641 tttggttcta ctgtcattat cgttttacct gaaccacttt ggggtatctc atctcttgtt
    14701 ctatcctttt taaattcatt gtctatatta ggtataacca acttttccat aaattttctt
    14761 ataaaagttg attttcctgt tcttacaggt ccaactactc caatatatat atccccctga
    14821 gtccttttgg atatatcttc gtatatgtta ttattcatat tattcctcct atacatctaa
    14881 tcttattaaa ttatatttag agttaagggt taatattctt aaaatagaaa aataaagacc
    14941 agcaatatta atttaattta catatagaaa tttgtaaatt tcaatgtaaa ttaaattaat
    15001 attgctggtc caaatagtag tgtattatat taactgactt tagtagtatt ttcatttgac
    15061 ttattattca tctcaataag ttctttacgt ctttcttttg tcatgttcat ccatataaat
    15121 gtaaacacca atccaattat ggctactata gtaagaacta tgaagtagta cctatatcca
    15181 gttacacccg gaaatgcatc caatatcttc cctgctgcta aaggacaaag tacttctgga
    15241 agatatccta atgtagcaac tattcctata gcagttcctg atattgataa tgaataatta
    15301 ccttcttcaa gtaacgaata gtgtaaacct tgaattgcat acatagatac atatattgca
    15361 acacatccaa tcaatagtat ataaatcata gatgattttg ttggtgtaaa tattacacct
    15421 aaaagacctg caatcataag tataaatcca taagatataa tctttgatga acctacttta
    15481 tctccaagta atccagaagc agctgatgct actggtctac aatactgagc taatattgag
    15541 attgcagatg caaacaccac agtagctcca aatgcttcag ttgaataagg cgtaaaataa
    15601 taaaatgaca tattagctga atatgaacaa aacattatta ttgttattat ccatgtatga
    15661 ggcattttta ttactgcaaa aaaggcttct ttatcaaatt ttgctgatac ctctttttca
    15721 ttatccttta atttgaaaaa tactaatact ccaactatta catttattgc cgagtataat
    15781 actataatag ctgtaagacc agatttatca cttacttttg atgaaatata cccaaatagt
    15841 atcaatacta gagatagatg aattgcattg gtaattccac gaccactttc cataaatcca
    15901 aaagcttttc cttgttcatt ttcagatgct aacattctaa cagcttttac aagagctggc
    15961 caaaaagtaa gtattgttgt tattccccat aaggcatgga ttaaaaacac aacaatatat
    16021 ggaggataaa gtgttaatac aagaccagat attcctgtaa taattaaaga acctgaaagc
    16081 aattttctgg ctgaaatacg gtctgctaaa aaaccaccaa aaaggtatga taccattgca
    16141 agtagaccat aaatgcttcc taagcttccc atttgtgtat ttgtaagatt aaatgcttgt
    16201 gcaaaagtat cataataata attctttaaa tatggtaaag catatataaa tgctcctgct
    16261 acaaagagta ttatcaagac tttgaaattt ttccaaatgc ttggtttatt tacttcaact
    16321 gacatacttc ctccttatgt aaatacctgt aaattttcat gataattaat tattgcttat
    16381 tttattgttt attcaatatt tcggaatatt tattaatata ttaggttaat ctatcaataa
    16441 tttatggtga gttatgagct aaaagtaaac tcttttagct caccataata attatatttt
    16501 tatttatact aacgtccaga gttattagat atcttttttt catagttctt ccatagcatt
    16561 aaacctgtta ttataacaaa aagacctcct cctatcattt caatctcata gattatatta
    16621 tcttttaaag tctccataac tggtgccgtt gagaaaagta tgccaactac agttactaca
    16681 agtaccattc tggcaatatt gatacaaact gaatcacttt ttgcaattga atatggtctt
    16741 tcttcatttg gtcttgtctt tctaagtcta atataagatg taaaaagcaa gacatatgga
    16801 aataatgctg ttaatgctgt catagtaaca agaacattgt atatattatc tactgatggt
    16861 aataagtttg ttcctacaag aagtagactc actattatag cctgaactat tactgcattt
    16921 gatggtatat tgtatttatt tgtaacagtc aattgcttag gaaatacacc ttctcttaca
    16981 tttccaaaaa gcatctttac tggacctgct atataaagta ttaatgctcc tagtactgat
    17041 aaagttattc caaatgctac tattcttata aaccaacttc ctatacctaa atcttgtgca
    17101 actttagcta atgcatctag tatccctgta gacgctgcaa ttttatctgg aggaagtatc
    17161 attgttattg ctactgaacc taagatatag attcctccta ttaaaacagc cacagttaat
    17221 atagctttag gaaagttttt cttagcatta tccatttcgg ttatgaaatt agcagtcgtt
    17281 tcagctcctg ataatgcaaa tattatagca gatatagaaa ctaatgaatt ggcatctatt
    17341 tttggtatta tattttggat tgtatatatc gatgctgatg gagctttttt gagaataact
    17401 acagacataa atgccatcac tataagtaat atagcaggaa ttgtagaacc taatgctcct
    17461 gtattcgtaa aaaattttcc aaatgccatc ccacgagtac ttactaagga caacagccaa
    17521 aatattatga gtgaaagtgc taaaataaac atcttattgt ttgataaatc tggatttcca
    17581 agcatatatg caatatttat agctaaaaat gtcaagaaag aagaatacca aaatatcttt
    17641 gatgtccaat ttagccatga caccataaat ccccacttct ctccataggc ttgtttaacc
    17701 cattctccaa gtccaccatc ttttggatat gttgcagcca actctgcaca tataagtgat
    17761 gcaggaacaa agaatataaa agcaaacaat aaccaaactg gtatagaacc aagacccaat
    17821 ccaaaactag aggcagtaga tttagctatc catctaatcc caaatagtgc tgatatattc
    17881 ataaatacta aatcccaaaa tccaattttc tttttcactg taattcctcc aatttcaaat
    17941 ttattcaaac tcatacacaa tgtattgatt taaatatcaa gtataagttc ttcaacactt
    18001 cttggataat tagttataat tgtagcacca ttcttaccta ctattgctgt atctgagtgt
    18061 ctaaatcctc caactccagg tatatatatc cctggctcca tagaaaatac cattccttct
    18121 tctaatatta attcattgtc aaatcttaaa tatggctctt catgttctga taaacctaaa
    18181 ccatgaccaa ttctatgatt tgaatataac tctagaccat actttgcaac aacagctctt
    18241 gctgcttcat ccaccattct tgctggtata ccagctttta ttgtatctaa tccagcttgt
    18301 tgagcctcta ctgcaatctt aaacacttct ttttgtcttt ctgttggttt acctataata
    18361 aaagttcttt cattttctgc tctatagttt tcataccaaa cctgtctact atgtattact
    18421 atatctcctc tttgaagtat cctagtattg gaatctaaat gaggttgtgc tgttctatca
    18481 atccctgaac aagtccagtt tgcaaatcct atatatgtat caggataatt ttcagaaaca
    18541 tattttagta aagcattatc ccccgcaacg tcaaactcca attcactcat cccaactcta
    18601 acattttcta aagacccttt tattcctata tcagataggt aacctgctat cttcaaaaat
    18661 tctatttctt ttgcatcttt tacatatctc atttcaaata ttttacttcc aacatctttg
    18721 atagcaaatg acttatcagt tatatactct gaaaaacttg cagatactat atctttttct
    18781 attccaacag ttgttccttt agggtattta tttaaaatta tatctaagta atgtttatgt
    18841 gatattccat gttctttcat ttctggtatt tcataataca catatacatt atcaactttt
    18901 gcaacttctt tagcatgtaa ttcttctaat ccaggtacta ttaattctat tttatcttga
    18961 gttactactg ttacaattgg tctagaataa gttattgctt taaatccact aatataaaat
    19021 tgattgtctg gttcaaatat taaagcaatt tcaatgcttt tttcattcat gtactttctc
    19081 aatctttcta gtctcatatt atttgacata atgcacctct ttcttaatat tcagataatt
    19141 tattcaatac aacaaggata aatatattat tttaaaattc ttaatatttt tagtacttgt
    19201 cgtatttgca tgtaaattaa ttttatttgt gattatttta tcataatcat gattattttg
    19261 tcaatcacga ttttattttt aaaatttttt tatattctag tgattttaaa ttatctaaaa
    19321 tataacgagt atacattgta ttttggaata ttattcttga tttatggtaa gtttaatgat
    19381 aaaatcacga ttatataaac tatattgatt atttgtaggt gaataaaatg acaaataaag
    19441 aattacaaaa gaaaaggata ttgatgtatt tcatagaagc tgctcaaaat attatggaaa
    19501 acgaaggtat agaaaatatt acacttcgta aggttgcaga tatggctgga tataatagtt
    19561 caactctata taaatacttt aaaaatttag accatttaat atcatttgca tctataaaat
    19621 attttaaaga ttataacttg aatatttcaa gatgtataga aaatgtcaat gatgaatata
    19681 agaaatatat aattatgtgg aaattatttt gtaagcattc ttttgacaat gctcaagctt
    19741 tttatcaggt attttttaac ttgtctagtg atgaacttag ctatataaca aaacaatatt
    19801 atgatatgtt tccagaagat ttaggtattc atgatagtga catatcttta atgattacag
    19861 gagaaagtat aaaggaaaga aataagatac tattaaacaa tcttgtagat actggatata
    19921 taccagctaa agatttagac ataatcaatg atataattat ttctttttat caaaatctat
    19981 tattcttaaa aaagaacaca ggaaaaaatt ctggtgatga tgaattaact atgaaaatga
    20041 tttcttctat tgaatacata ataaaacatg ctaaataaaa ttaaaatatg gctgtctcaa
    20101 aatagagata agcctttttt attgttgaaa taataaaaat atatttaatt tcatataaaa
    20161 aaaagtgcct cgtaaactaa aaagttcatt ttgagacacc cctaaaacaa atttattatt
    20221 tattatacaa tagtttatat atcatcacct aaaactactt cttccatttc atgcttttta
    20281 cttctcatca ttagttctat tccaacttct ttaggatttg aacctttatt tattacagaa
    20341 tatatagcat tagttatagg catatctata tctaattttt cagcaacatc atgtgctact
    20401 tcagtagcag ttatgccttc tacaaccatc tttacttctt ttaaagtatc ttctaaactc
    20461 atacctttac ctatgagtat accagctctt ctatttctac tatgcatact tgtacaagta
    20521 actattaaat ctccaatacc tgaaagacct gcaaaggtag acatattagc tcccatagca
    20581 attccaagtc tgctcatttc actaatacct cttgtcataa gggcagcttt tgcattatca
    20641 ccatacccta atccgtcaca tatcccagct ccaaatgcta taatattttt taatgctcct
    20701 ccaagttcta ctccaactat gtctggattc gtataaactc taagtttagg gctcataaat
    20761 aaatcttgta tcatctgtgc tatttttaaa tctttagaag caactactac ggtagtagga
    20821 atatcccttg ctacttcttc agcatgagat ggcccagata gtattacata tggattttgt
    20881 ggtaattctt cttcacagac ttgagataat ctaagcccag tccctttttc aagaccttta
    20941 gctacattaa caataacttg tccttctttt ataaatggtt ttattttttg gcaagtactt
    21001 cttacagcct gtgatggaac tgctaaaact attaccttac aatcttttat agttttttct
    21061 atatcagtac ttatagttat attgtttgga aataatactc ctggtaaata gtctgtattt
    21121 tctttagttc tgtttatttt tttagcttgt tcctcttttc gagtccacat gctcacatca
    21181 ttaccttttt ttgcaagccc taaagctaat gcacttcccc agcttccagt acctaataca
    21241 catactttct ccatgtttaa caccacctga gtataatata tttactattc tttcttttga
    21301 ccaatttttc tctctgtccc atttaataat cgctttatat ttgctctgtg attatatatt
    21361 actgatgcag ttaagaacag agctactatt aaaccagctt tattttttac cataatcata
    21421 aatattggtg aacatcctat tcctacaaca gaacccaatg aaacatactt tgttatagct
    21481 accaccaata taaatactgc tagacacatt agtgttatta ctggatttac agctagcatt
    21541 gcacctagtg aagttgcaac acctttacct cctctaaatc ctaaaactgc tggccaatta
    21601 tgacctgcta caacacatat aactgccaga tatccagcta aaagagtatc tattccaacc
    21661 aatcttgctg caaattctga tattaaaaca gccattacac ctttaagaac atcacctaaa
    21721 aatgtcattg ctcctgctct ttttccaagt gtcctaagta catttgtcga acctgcatta
    21781 ccagaacctt gagtccttat atcaacccca gcaattcgct ttgcaactat gtatgaggta
    21841 gatatatttc ctaaaagata tgcaactaca gcaataatta tataactaaa tatctccact
    21901 gaatttcccc cctttagtta tattttaaga tatttatttt ttattttttt gtctatactc
    21961 aaactttatg gaagttcctt caaatccaaa attttctctt atcttattct caaggtatct
    22021 ttgatatgag aagtgagtta aatccttatc atttataaac aatgtaattt taggaggtct
    22081 aatgtcagtt tgagtcccat agtaaatttt tagtcttcta cctttgtcag atggtggttg
    22141 atttaacatt acagcttctc caattacttc attcagtgct gaagttgata ttctcttaga
    22201 atgttcattt gacacatatt caactgtatc tagtatcttg ttcattcttt gattagtttt
    22261 tgcagaaaca aatacgattg gagcatacat cataaatgga aatttttctt ttatatcttt
    22321 tgtgtaatta ctcatagtct tattatcttt ctctattaaa tcccatttat tgattacaaa
    22381 tatgcatcct tttccttcat catgtgctat acctgcaacc tttgtatctt gttctgttac
    22441 accttctaag gcatctatta ctatcaatac tacatctgct ctatctacag cactcatagc
    22501 tcttattaca ctgtattttt ctattgtctc atatatttta ctttttcttc taagccctgc
    22561 tgtatctatt agaagaaatt tctgtccatt tttttcaaaa taagtatcaa ttgcgtctct
    22621 agtagttcct gcaattggac ttacaattac tctttcttct ccaagtatct tattgagtat
    22681 agaacttttt cctgcatttg gtttacctgt tatagctact cttattatat cttcttcata
    22741 ctctgtatct aatcctgctg gaaaattttc aactatctca tctaataaat ctccaaatcc
    22801 catactattg gctcctgaaa ctgcaaaagg cgttccaaat cccaactcat aaaaatcata
    22861 tatattatca aattgacttt gactatcaat cttattaacc actaagatta ctggtttttt
    22921 tgtctttcta agcaattgtg caatttcttt atcagcagct gttattccag ctttaccatc
    22981 aactataaaa agtattacat gtgacatgtc cattgcaagc atggcttgat ttctcatttg
    23041 agataatatt atatcttcgc tatcaggttc aattcctcct gtatccacta atgtaaaata
    23101 tttatctaac cactctactt cagcaaatat tctatctctt gtaactccag gtgtattttc
    23161 aactattgat atcctttttc ctgcaaattt attaaatatt gtagacttac caacgtttgg
    23221 tctcccaact acagctacaa ctggcctact tatactcatt ttatttctcc ttccatcttt
    23281 tgttttctat tttaaaattt tatccacaaa gtcttttcct tcattcaaac aagggataat
    23341 ttttattctc ataagttctt ctaattgatt taattcaata ttatctaaga aaatttcttc
    23401 atctgctttt agcatacttc ttgttatata aagagcttct cctaattctt tatcttcaag
    23461 ttgttctttt aaatccttag ctgttaaaag acctgataca gttattgtct ctccaaaaaa
    23521 cttgtttttg atttcatata catttacttg aagattttta aacttgtcca tcatagcatc
    23581 tgccatactc tgtataaatt catatgcaga atgaccagta gctattgata ctttcttctc
    23641 tctttttaga atattctcag gcaatatatt tagatactct tcaatctctg tttttaactt
    23701 acgtatcata cctacaccat cttcaaactg taaaaaacct tcatattctt catatccagg
    23761 caattcacta ttagatagta tataaaattc atctgataaa aatgcaaatc gagtacctaa
    23821 tttttcaaga tatttctgtt gtatttgatg tatttgctct atagttttac ttgcgctctt
    23881 atcattaaat atatttaatt ctactagatt ttctctatgc tttgtaatcc caactggaac
    23941 tatcgcaaca ctgtttacat atggataaag ttgagctagt tcttttattg ttctatccaa
    24001 ttcctttcca tcatttatac ctggacataa aacaatttga cagttcattt ctatatgagc
    24061 atctgccaat ctcttcatta taccatataa ttttcctgca aatttattgc ttatcatttt
    24121 ttgtcttaac tctggattag ttgtatgcac agatatattt ataggactta ttctatattt
    24181 tataatatta tttatatctt cttcactcat atttgtaagt gtgacaaaat ttccttgtaa
    24241 aaaagataat ctcgaatcat catctttaaa ataaagagtt tctctcatac cttctggcaa
    24301 ttggtctata aaacaaaaca tacacttatt tctacagctt ttagcttggt caattatcgg
    24361 atttgtaaat tcaacaccca aatcttcatc atagtctttt tctatctcgt atatgtagac
    24421 ttcgccatct tttttttgta tttctacatc taaatattca tcacttagta agaatctata
    24481 ctctattata tcatgtattg gctgttcatt cacagatata agtaaatctc ctacctctat
    24541 acctatttct tctgcaatac tatctttata aaccttactt ataatattat ttactttttt
    24601 tacatttact tccaatattt tcaccactct tttgtattca tcaatgctta ttataatata
    24661 ttttaatatg caatttattt atttattata ttttatgata gcatttttaa gcatttcatg
    24721 tcataataac acattttaat tctaatagtc aatataagta aatagctata aaatagatta
    24781 gaacaaataa tattcaaatt taagtttctt aaaaatttga atattatttg ttcttaaaaa
    24841 aattttataa atttaatgtt ttactatgat taacgtccca tttgtcatat catgaaccat
    24901 tccacctaca cactttgaca tcaacaatgc cttattttgt aagtctttct catcatttgc
    24961 ataaaatatt ggacaacctc caccattttt catattctta tcaagtgtaa ctatagctag
    25021 ggtatattca tttaaaccta tatccattcc catcttatgc acttcctttc tttcctattt
    25081 tataattttt tagtgataag ttttttcctt tagagcttga aagtattggg catgacttta
    25141 cagcttccat tactttttcc atattcttat ctactggtaa ataagcaatc attatacttt
    25201 catcctcttt atttcttcta ggtaatggta cgaatgaagg ttctccataa tctccatata
    25261 aacctaacct tgaatatata ttgtatacta ttgcttgtct ttgaccggag tcaaataata
    25321 ttcctgcatt agcataatcc ttatttttag gaattatttg tattcctaca cctctattaa
    25381 tatatacttc tctatcactt tttagaccta tatttgttat accttttaaa tctcccacct
    25441 ttagtataga ttcgtccaca aaactaattt cagcaggcat tacatcagct atgtctccaa
    25501 tactttttct agtaagaagt ttttttaata taaaggctaa cactaatcca caaattgaac
    25561 ttattaccaa actcatccct tcacttattt tcgtttctgc aagtattaca taatacaatc
    25621 ctattgttaa aaaagatgta actatacaca tataatttct tacttcatag gttctagcta
    25681 tctcttctat gaatgcagca cctctcttta caagttgaac ttcctctaaa ttttgcaatg
    25741 tatttcttct atttgctctc acttgtctaa attgttctgc tgctagagat aaaaatgtta
    25801 tggatgtata agaacgattt ataagagctg gaaccaataa tgctcctaat gaagaagcga
    25861 cgaatgctaa tataagttga gatagtaaaa catttggttg cgttggatac tgtttttggt
    25921 ctaaattcaa cattataatt ctagatgtta taccaataat aacagcaaca aaaaatactc
    25981 tatccattaa atcactccta aaatatttaa tttgaaattt tacatgtaaa tctacaaagt
    26041 ctttctagaa aaatcactct gctttccttt tgatgtttct atgataggtg tacttttcac
    26101 tacatctatc atgacatcta tatctttgag tattggcata tatggtataa ccacagtact
    26161 tttttctaaa ttggtcttag atatagcaac aatatcaacc tcatctacat ctctatctat
    26221 ccccatatga ataaatagat tatgtattat agcttgtctt tgccctatat catttactat
    26281 tccaaatgca cctaaatctc ttggtataac ttctatggcc agacattcat ttctatactt
    26341 ttctcttgta ctttctagac ctatattagt tattattaca tcatttacca ttaaaatagg
    26401 tccttcaaaa cttatttttg caggaactat atctgctata tctgctatac tgtttcttct
    26461 taaaaatctt ctaaaaatca agccaacaat agctcctgac acaatagcta aaattgtgca
    26521 atgaaaaaag ctaaggtcat actttcttgc aaaaacgata taaactatcg aagatactag
    26581 tgcagaaaaa agacttatat aacttctaga ttcatacgta gatgctattt cttcaacata
    26641 agcatctcct tttggtacta attcttcatt atcaatattc tttagtgtta ttctttcttg
    26701 ttccgcaaga ccttgaaact gttgtattgc tactgcaaaa aatgtcaagg ctgcaaactc
    26761 cttatctata agtgcaggta atgctatagc acctaacgaa gctgaaagcc cagatataat
    26821 tatctgttct aaataatctt gtggtcttga tgggtattgt ttgtctgtaa ctcttaaaac
    26881 taatcctcta cataatattc ctacaactaa tgcaactata aaagagtgtc taaataaatt
    26941 tgcattcaat aaactttctt ccattttctc agctccttct cttatatagt ttgtgcaaaa
    27001 aacaaaaaaa attcccttct atttaaggaa atttttttgt aatattgtaa ctataaattc
    27061 gctaccaatg ccaagttcac tttttacttt tatacatcca tttagtgatt tgactatatg
    27121 ctttgttata gccaatccta aacccgttcc tcctacatcc ctacttcttg ctttatctac
    27181 cctataaaat cgttcaaata ttcgttctac atcttctttt ggtatcccta caccattgtc
    27241 tataacttta attacgattt tttcttcatc ttttaacact acaacttgta caatcccatt
    27301 atcttgggta tactttatag cattatcaac taggtttaag aacacttgct ttatatagtc
    27361 tttattggat agtatactta ttgatttatc atcacattta tataaaactt ctatattttt
    27421 ttcactagct gaatgttgag ttatttcata tacctcttta aatacatcat atactacaac
    27481 attttccata agaagagtat ctttattttc tacaaatgat aacagcaata tatcatcaat
    27541 caaccttttt aatctatctg attcgctttc tattatttct aagaatctat ttctagtatt
    27601 cacatctata ttttcatttg actttagtgt ttcaacaaac ccacttatag atgtaagtgg
    27661 tgttttaagt tcatgactta catttgcaac aaaatcactt ctcatatttt caagtttaac
    27721 ttttttagta atatcttcta tatttactat cgaacctatt attacgttgt tagtattctg
    27781 aagataaact gggtctacct ttatcttata tacgatatca tctttagtag taatattagc
    27841 agtttcatta tctttagaac caataaattg aagtatttgt tttaatattt cttcttcttt
    27901 tattacaaca ttaatattat gaccttcaac taattgattt ggttcactct ttatcatttc
    27961 ttttgcttca tcatttatca gaagtatatt tccatttaca tctatagcca aaattccatg
    28021 agatatactc tttaatatag atcttaactg taaatgttta tactgtactt cttctaaggt
    28081 tttatccata ttctttatca tatgattaaa atttctagct aattcaccaa gttctccttt
    28141 ggctgatatg ttaagcctag catgatattc attattactt actttttttg agacgtatat
    28201 aaactctttt aaatatttcc ttaatgttat tgtatatctt acagctaata taacaatggc
    28261 tatggacaac ataacaataa aaaaatatat actatttaaa tcttccacaa gataacactc
    28321 ctaaaatata acctttttaa tctattttat accctacacc tcttatagtc tctatatatt
    28381 tttccgattt atcttcatct tctatttttt ttcttaaata tcttatatga acatctactg
    28441 ttctagtttc tccatagtat tcataccccc atattttatc caaaagataa tttcttgaaa
    28501 gtacttttcc tttattttga attaataatt ttaacaattc aaattcctta agagttaact
    28561 ctatcttttc agagcctttg gtaacttcat gttttgataa atctagtttt aaattgcctg
    28621 tagtaagtat attgttttct tcacctaagc tagtcaaatt atatctcctt aaaacagaac
    28681 taatcctagc taacaactct tttatactaa atggcttagt tatatagtca tcagcaccta
    28741 tttcaagccc ttcaaccttg tcattttcca tatttttagc agtaagcatt ataacaggaa
    28801 tattttttaa gtccttatca cttcttattt ttctcaaaac ttctattcca cttatatttg
    28861 gtaacatcca atctaaaagt attaaatctg gtttaatttc cttagccttt ataaatccgt
    28921 caaatccatc atatgaataa ctaacttcgt aatttgacac ctccaaattg aattttaata
    28981 gctcaactat atgcatttca tcgtctataa caagcacttt agtattcatt aaaaagctcc
    29041 tctctatttt atctgtagta ccgttcctat tcgttctgat gccttattat gttttctata
    29101 agagtggaat ttatctgctc tacaactagt gcataaattt aaatttatta tattttcttt
    29161 tttaactcca ctacatctaa gcatatactc attaattttc cataaatcta aatagtaact
    29221 tccctctttt attatataga acttttcatc attatttgta agaattgtgt taaatttttc
    29281 tactaaatct tcagacactt catagcaaca tggtccaatt gatggcccaa ttatacatac
    29341 taaatcttca ggaactgttt tatagcattc agacattaat tttattgttt tatgacctat
    29401 attactaaaa gtccctctcc aacctgcatg agccagtcct atggctttat ttttagcatc
    29461 tataattgat ataggtacac agtctgctgt aaacagtaaa agtggtactt tttccaagtt
    29521 tgttataagt gcatctccat ctcttctttt ccctatagta tctttattga ctatattaac
    29581 tatatctgaa tgtatttgag aattactagt tatattttca aatgtcaaat cacattcttt
    29641 acatactttt aacatatctt ctctattttt tgcatctata ttcttacatg ttataactag
    29701 atttacagaa tttaattttt catcaagttc ttcacaatta ccacttaaat taacatactc
    29761 tttaatatct tgtacatttt ttatatttat ataatctttc atcatttgtc tcctttttct
    29821 atcagtatac ttttaagttc atttacaaaa gtatttatat ctttaaattg tctatacaca
    29881 gaagcaaatc ttacataggc aacctcatct aactctttca atttatccat taccatctca
    29941 ccgatttttt tggtttcaat ttcttctata aaacatttat ttatttcatt ttcaatatgt
    30001 acaacaatac tttcaatctc ttcaatagaa acaggtcttt tttcacatgc ttttagcaat
    30061 ccatatttta tcttttctct atcaaaatat tctctactat tatccttttt aatgaccatt
    30121 aaaggagttg tttctatttt ctcatacgta gtaaacctct ttttacatga ttcacactca
    30181 cgtcttcttc tgatagattt taaatctgta tgtctagaat ctattacctt tgattcttta
    30241 taattacaat aaggacattg catctatatt cctcctttgt ttaactatat ctcaaactca
    30301 tctaagctta attctgaacc tatatttact attattgtat cacaacctat tttaagtata
    30361 tcattccaaa atataacttc ttcatcccct cctcttgaaa aaaaacttct acttccatct
    30421 ccaaaaatgg taaatgagac taccttacct tcgtgaatat ccatgtctat gtctattata
    30481 aaccccatcc tttttccatt ttttacattt ataatttctt tttccattat atcagaaact
    30541 ctaatcatat tgtactcacc ctttctttaa aaataaatat gtatcgaagt aaaaaaaaat
    30601 gacctatata ggtcatttaa attaaaataa tgtttacagt ccatggatta cttatacata
    30661 ttttctcata ttttttaaag catttttttc aattcttgat acttgtgctt gagatatacc
    30721 gatttcatca gcaacttcta tctgagttct tcctttgtaa aaccttaaat ctaataccaa
    30781 cttttctcta ctatttaatt tcttaatagc ttctttaagt gatatttctt gcaaccaatt
    30841 ttcatcagta tcttttttat cttgaacctg atccataaca aatattgcat ctccattgtc
    30901 ttgatatact gggtcaaaca gagatattgg gtcttgtatg gcatcaagtg ccattacaac
    30961 tgattctact tctaattcta attcctttgc tatttctgat actgtaggtt ctttagaatt
    31021 tgttctaatt aatctttctc taacttgtag tgccttatat gctatatctt ttaatgacct
    31081 acttactcta attgggttat tgtctcttag atatcttcta atttctccta taatcatagg
    31141 aacagcataa gttgaaaacc ttacattttg gcttaaatca aagttatcta tagcttttat
    31201 aagaccaata caacctattt gaaataaatc gtctatattt tctcctctgt tgttaaactt
    31261 ttttattaca ctcaagacta atcttaaatt tcctcttaca aactgttgtc tggcttcttc
    31321 atcaccattt tttatttgta ataaaagttc cttcatttgc ttatttttaa gaactggaag
    31381 ttctgatgta ttaacaccac atatttcaac cttattaact tgcatatatt ttcagtcctc
    31441 tctcaaaagt attcatctat tgaaattatt tacatttcca atttttttat actttttaag
    31501 aagaattaat ttaacattat acaaattttt tcatttcttt ttgcaacctt gagattattt
    31561 tcttttcaag tctagatatg taggactgtg atattccaag cattccagca acttcttttt
    31621 gtgttttttc aataccttta tcaataagac caaatcttaa ttccataatt tgcttttctc
    31681 tgtcacttaa tctgtcaagt gccataacca acaaatctct atctatttct tcttcaatta
    31741 ttttgtatat ttcatcattt tctgtaccca atacatcaga taataaaagt tcatttccat
    31801 ctaaatctat atttaaaggt tcatcaaatg atacttctgt tttcttttta ttattttttc
    31861 ttaagtacat taatatttca ttttctatac atctcgaagc ataagttgcc aattttatat
    31921 ttttattcag tttaaaagta ttaactgctt ttatcaaacc tatagttcct attgaaatca
    31981 aatcttctac atctatacct gtattttcaa attttctcga tatgtagact actaatctaa
    32041 gatttctttc tattaaaatt gactttacac tttcatctgt ttctagcttt tgtaaaagct
    32101 ccatttcttc ttctggtttc aatggaggag gaagtatatt tgcccctccc atatagtata
    32161 ttccctttgg ctttattatt tttaatttaa tacctaacat agtaataaag cttattattc
    32221 tttctttcaa tcgtaacatt ccttgtcccc cttaaatttt cacctaaaat ccaggcaata
    32281 tatttggatt cattattgct ccatattctc tatcattaaa atttgaaata ccaagtatta
    32341 tatttcctat cttttgctca tctacttcta tatagtcagc ttttaagcct attattatgc
    32401 ttgtcttatt acttccagca tgtttataag gtattattct aactctacct gaagttttat
    32461 catctaaact tcctataatt tcttgtgctt tcttcatatc tatatcttca taattaatat
    32521 ttaatagttt ttctggaata aatccttcta acacactaga cttaactatt attacatcac
    32581 tttgacttat tgggtctttt aacaaattac cactatctac taaagcttta cagcaaaaac
    32641 ttttttctag taagtttata tttatagtct ttgtaagctc cttaatgtac ttaagcattt
    32701 tcaaatcttt ataaatgtat tttaataatt cacaactcac ataagtacat gcaattaaga
    32761 aagatatttt taagtgactt attcctgtaa aataaattat aaaataagtg cttccagaaa
    32821 taaaaatgtt tactagataa aaaactaacg ctacatgaac ataatctttt ttgctcttgc
    32881 ttctaaatga aattaaagtt attatgctca tgattattat tttaaatggt acagtaaata
    32941 gtatattcat tgatggatac aaataagcaa cagaataggc acttcctaaa ctagccccca
    33001 ataacttatt ttttttagga ttatatcttt tagtaagaat agaagtacaa cttataataa
    33061 tataatttat tactaggttt tctataacat agtactcaat atacaccatg tatcccccct
    33121 taaaaccttt aaacatatta taagatagta tgtacaaaat tttatgtcac ttttgatggt
    33181 cgaatccaaa acaaattcta tttaaaaaga acaatgatat atgtcttata ctttatgtcg
    33241 tcaaaagata tttttttaat gccaaacaga tagacttttt tgtagaatcc aatatatcta
    33301 ggtagaagtt attcgcttta cttttggtat atttataaaa aaaagactac ataatttaat
    33361 aatatatcaa gtaaatcttt tacttatata aaatcaaatt atatagtctg taaattcaaa
    33421 tataaattat tgtgctagta atccatttgc atattttgca gattcattta gtgcttgttc
    33481 tggagttatg tctccagcta tcatcatttg aagttgtttc cataaatatt catatatctc
    33541 tactccatga ggtccaactg tcaatggtct atacatatgt ttatctcttg tcaccatttc
    33601 ttcaaatctt gggtctcctt ggtatttttc acctttagca actggagctc taggtatttc
    33661 tttgtggaaa gcttccattg attctttgct taacatatac tcaagaagtt taaatccaag
    33721 ttctttattt ttacatgctg acattaatgt taaatcatct actgaagcaa aacttccaac
    33781 tgtcttatct tctaatgatg ttacatatcc ccagtttaaa tccgggaatg atttatcaaa
    33841 tgtacttgta gcagcagagg atagcattat agtaaatgca gcttttcctg gtccaaatac
    33901 actttcaatc atttcattac tatcttttga taaagcatct tctggaatat actttttcat
    33961 atcatttata aagtttgcag ctttcaagcc ttctgcatta ttaaatttaa ctgattttaa
    34021 atcatcatta tatatatctc caccagcttg ccataaatac ggataccagt tccagtttaa
    34081 gcttccaaat actttagaac cccaaccttg tgcaagaccc cactggtcga tttttccatc
    34141 tccatcagta tcttttgttg ctttttcaca gattctttta aaatcatccc atgtttttgg
    34201 aggtttttct cctaattttt ctagtatatc tttattgtag tacaatacgc ctggattagc
    34261 agcttctata ggtaaaccat aaataccacc catcattttt gcatcatcta agtatagata
    34321 attatctgaa gttcctgatt tttctaaata aggtgttaaa tcttctactg cacccatttc
    34381 tataaattga gggaacatct ctgcatacat gtatcctata tctggacctt cacctgcact
    34441 tattgctgtt gcatattttt ctgcgtagtt atcccatggt actatctgaa attcaatttc
    34501 acagttattt tctttttcaa atttttcaaa tatcggcttc catgcatctg catcatggtc
    34561 tgttaatggt gcagaccata caactaattt ttctttaccc tctttgcctt tagaatcttc
    34621 tttttttgaa catcctgcaa gaattgatac tgatagaatc cctaccataa ctaaagaaag
    34681 aacctttttt agtttaatca tgcttaatcc cctttcagac tttaatttgt ctttttcctc
    34741 aaatgtttac atttaattca gatttaatat taacaaataa gactactctt gtctaatcat
    34801 aaaaaactat actaactcct ataactatat tttttttcta tacctattag atttaattca
    34861 tactaaaaac ttacttttta aattttatca atatttaaaa atatttttaa gtctagccac
    34921 aaactaacta tctaaattga acaaaataaa aagaagtcta ttgacttctt tataagctta
    34981 catattatct tcttcttctt aggaatgtag gtatctccat gctctcatca tcatcttctt
    35041 caattatact tgccttttta ggaggctcta ttttttcctc agcaattact tcttcttcaa
    35101 tttcttttac agcttgtttt actgttgtat ttaatgaaga acgtatgctt gatttaggtt
    35161 tagtatctaa atctaaggca ccattttgta atccttcaaa tcctgttgcg attactgtaa
    35221 tcattatttc atcacctaaa tcttctttta tagaagctcc aaatataaca tttgcttctg
    35281 ggtcacagga ttccataact aaagttgatg cctcattaac ttcaaataat cctaagttag
    35341 gaccacctgt aacattaaga agtactcctt tagctccttg tattgatgtt tctagaagtg
    35401 gagattgaat agcttgtctt gcagcatcaa ttgctctagt ttcaccacta gcactaccta
    35461 tacccatatg agcaagtccc ttgtctttca ttatagtagt aacatctgca aagtccaagt
    35521 ttattaaccc ttcaactgct ataaggtctg aaattgattg tataccttgt tttaatacat
    35581 catctgcaac tgcaaaagca tctaacattg atgtattttt ttgtactatc tgtaaaagtc
    35641 tatcatttgg tatcgttata agagtatcta cttttgattt aagttctgct attccacctt
    35701 cagcgttctt cattcttatc ttaccttcaa atgcaaaagg tttggtaact acacctactg
    35761 taagtatccc catttctttt gccaagcctg caaccactgg agcagctcct gtaccagtac
    35821 caccgcccat tccggctgtt acaaagacca tatcagctcc ttgaagtaac tttactattt
    35881 catctttact ctcctcagca gctcttttcc ctacttctgg atttgctcct gctccaagtc
    35941 ctctagttaa tttttctcct atttgaactt tatattcagc ttttgatgta tataaagctt
    36001 gtttatctgt atttactgat ataaattcaa cgccttttag ttgagcttct accattctat
    36061 tgacagcatt gtttccaccg ccacctacac ctattacttt aatttgtgca cattcttcta
    36121 attctacgtc aaagtttagc atcataaacc cccttctctc atgattcaaa gttatcgtat
    36181 gtattaatta tatcattttc ttcttttatt ttgttaacct ttaagtaaca tattccacaa
    36241 aaacgtaaat tttccttttt aaatttctta cttatattgt caaatattac tctttaagta
    36301 taaaataatt tacgtatata ttaaatgctc tttaattttt acgttttttg ttcataatat
    36361 tactaataat atatcgtcta attatagata agttattaaa caatctcata ccaaaaacta
    36421 gtacagcaac atagtaaaga gaaactccta acttttctcc tatataagtc aataatatag
    36481 ccaatatagc attacctatg aaaccagtaa taaaaattac attatcatag ttatcttcaa
    36541 aattggattt tatcgctcca aaaatagaat ccattattgc aagaatagct actgacatat
    36601 atatggaata atccatagaa tatgtaaatg gaatatagta acctactact acaccaaatg
    36661 ctaatcctcc taaaacccac aacataaatc ttcacctctt tattttactt tgaaacacaa
    36721 ctacattaca atccttttta ttaatttttt ttactttttc tttatttttt tgtatttttc
    36781 gttttatttt gcaaataaat tcactttatt cccattattt tcctgaactt ttatattaat
    36841 tccatatata tccttaagag atttagcata tgattctgga gagtttatag ctgcactcaa
    36901 taaatctata tctcctatag cttttattat aaatggttgt ccatatgtag tatcatttac
    36961 tgtaatagta gctcctgaac attttatctt acttgttgct agtactcttt ccccatttat
    37021 agaaattgct cttgctccag ccttttttaa atcatttaaa actctcaaaa tatctatatc
    37081 atgtataatc aaatcatttg gattctgtcc gtcttttaac tctctctcac tatccctcat
    37141 agtaatagtt atgcctggcc ctgtaacagt tgaataacca cttaattctt taacttcttc
    37201 aagctctttt tgcataagtg tttggataga ttcatttcca ttcttttttg cttctttata
    37261 ttcattcaaa gtttttttgt tgtttttaag agtttctttt aaatttttta tttctttttt
    37321 tgtattttct acctcacttt caatactttc agtttgacct aatgttatgt atactctatt
    37381 tgggtctagt gattttatat aagttgatat gaaaatgcct aatatgaatg ctcctaatat
    37441 aactattttc tttttcatac tattatttcc cctctgcttt gtttatatca ctatgaccat
    37501 ttatttctat attgtcttct ttggtcactt ttactttggc attataatat gtttctattt
    37561 cccagacaat accatacttt atattaagtg ccgaagccaa tgtatcagaa tcaccaattg
    37621 cttttattat aattggttct tttatgacag tgtcattcat acaaagcttg tcttctttta
    37681 aatacatata tgtattaaaa actattctct ggtcgtttat agatatggca cttgcttgtg
    37741 ctgaatttaa tttatttatc attgacaata ataaatcata attatatagt atactatcat
    37801 ttttatcaga gtttcctaag tcttttgtag aatttatctc aatttttatg cctgttcctt
    37861 caacatctgt atatccagct aatgtttcat atttttctat ttctgactta agtatgtctt
    37921 gttctccttt attgtttttg cctctataag tctctatatc tttcttcaca ctattaactt
    37981 ctgattgtag attctctttt tctgttttta aagatttaag ttcttctgta agttgctctc
    38041 ctcttttaaa agttgtcatc cctctatttt ctatattaat aattttaagt tgtaaactaa
    38101 caagaacacc caatacaaca cttcctatga ttatactttt atttataaat ctttttttca
    38161 atatatcact tccttacaat tgtctatcct tctggactat acactgccaa ctttccatag
    38221 ttaagattta tagtccctcc attagtattt ttattttgca ggtcaatcag aattttactt
    38281 accctagata tattataatc taagttatca tcattagaaa gtaagatttt tatattactt
    38341 cttgtaagca tttctatatt gctttctttt tttaagttta cataatttat ttttctataa
    38401 attccttctt cttttaaata atttaaagtt ttaaatacat tctccttagt tttataattt
    38461 ttaaatttta tagatttatt atcatcaacg ctataatcta catctactat caagtctttt
    38521 ttactttcat tagaacctct tagttcttcc aataaatttc cttttttatc tatataacaa
    38581 taattatctt catcttttaa tactgcaaat atttcttttt cttttaaact tataattatc
    38641 ttattgggaa gttttctttt tatttccaca ttttctatat atggattttt tataagttta
    38701 tttttcatat ctttaaaatt gtatgcaaaa atattttcat ttagatttat atttagttct
    38761 ttcattatat ttgatttggt caccctctta tttccaatta catctatttt ctttacatca
    38821 aataaatcac tttttacaat tatacatata caaaaagata acataagtat aaaaactaaa
    38881 actatcatga cattattcgt atttaacttt cttctttttt tcaaatataa tcaacccctt
    38941 tggttaataa atacaccttt agagcttgtt tttcctacaa aaaaattata atatttaaag
    39001 tcaaattttt gcattttatt acataacatc caaataaggt attaaatttt ataaataaat
    39061 caatatttca tcaaaataaa catagtatac tacatactat ttatatattt aaatctgtat
    39121 acatacaaat aaacccctaa tttataataa tttagaaaat ctaatatatt ataaattagg
    39181 ggtaaatatt tacttatctt ttctttattc ctattacctt agcttgacct tctatacttg
    39241 gagtcgtttc tttttttatt tcttttactt ccttaataac tttttccttt tttgtttttt
    39301 tagaagttga cttttgtgtt gaattgtata ctttcattat ctcatcatat ataaggtcta
    39361 tggcttcagg cttacctata gttttacttg catttgccat atcaactaaa agttctctat
    39421 ctcctaaaag tttaaatact gctgtattta ggctctctgg agttagattt ttttctaaaa
    39481 tagcaattcc tgccccttgt ttttctatac tcttggcatt atactcttga tgattttcag
    39541 cagtataagc tttaggtatt attatagatg gctttccaag agccgttatc tcagctaatg
    39601 aaattgctcc tgcgctacct ataaccaaat cacttgctgc aagtgcattt gccatatctt
    39661 ctaagtaagg cacaactttt tggtatggtt taagatttat atcgctaata cttcccataa
    39721 attcatcata atagcttttg cctgtagcaa atataaaagc tatatcttca tttaccatat
    39781 tctttattac aagtctcatt gcatcattta tttttcttga acctccacta ccaccatagc
    39841 aaagtaccat tcttttttcg tcacttattg atagattctt tcttgcaata ttttttcttg
    39901 ataataaaat ttcttttcta actggatttc ctgtaaaaac taatttatct tctgctgcct
    39961 ctggaaatct tttatgcgaa tcttcaaaac ttgtaagtac ctttgtaact gttttagata
    40021 aaatcttatt agttacacca ggaaaagaat tttgctcatg tattatggct ggtattttcc
    40081 ccatagatgc attaaataaa acaggtccac taacatatcc accagttcct ataactatat
    40141 ctggtttaaa tttcttaaca atctttcttg attgctccaa acctttaaaa agcttaaaaa
    40201 ctctttttac attatcgaaa tctatttttc gcttaaaacc ttgaactgtt acagtcttta
    40261 attcaaatcc atacttagga actatttctg actctattcc cttttccgtc ccaacaaaaa
    40321 ttatctcagc gtctggatgc tcatctctta ttttgtttgc aatagctata gctggataca
    40381 cgtgccctcc agttccaccg cctgataata aaactttcat caaatcatca tctcctgtta
    40441 attaattttg acatgctttg agatgtttaa cactattcct acagctccca taaagatggt
    40501 gagtgaagtt cctccataac ttataaatgg tagtgctaca cctgtagctg gcattgatga
    40561 tgtcgcaact gctatattta aagctgcttg tattccaatt tgtgcaccta tacctataac
    40621 aaccatacaa gcaaatacat tagaagtctt caaagctatt cttacacatc tgtagactaa
    40681 aactacaaat agcataataa ctattataca accaatcaat cctaactctt ctcctattat
    40741 agcaaatata aagtcatttt gtggctctgg tatataaaaa tacttttgtt tactctttcc
    40801 taagcctaga ccaaacaatc cacctgaacc tagtgcatat agaccttgta ttacctgata
    40861 ccccttacca agagggtctt gaaaaggatc taaaaatgat gtaacacgac taagtctata
    40921 gggttcagca attactaatg cagcaaataa agcagcccca ctccctatca tagcaaatac
    40981 aattttcata tccattccag caacaaatat cattacaaaa gtaactagaa ttacagtacc
    41041 tgctgttgac aaatttggct gaagtattat caacgcaaaa aatatccctg gaactacgag
    41101 aagtggtaca acaccttttg tcaaagattt tattttatca taattttttt caattaattt
    41161 tgcagttaat attattgtag caaactttgc gatttctgca ggttgaaatg ttaaagctcc
    41221 tattcccaac catctttttg ctccgtttgc ttctatccct aaaggggtca aaactaacaa
    41281 taataatact actgctatag ctccaattgc tgtagcattt ttcttccaaa aactataatc
    41341 tattcttgat gtaataatca taactataaa tccaagtaca gcatatatta cattcttttt
    41401 tagaaaatag tacgcatcat tgtgtttaaa tgaagattgt ataaaacttg cactaaacac
    41461 cataactatt cctacaaata ctaaaagcat agtagtgtaa aacactactc catcaaattc
    41521 agtcttcatc cttatgtcaa tttgtttttt caaattttct ttaggcatcc aactaatcta
    41581 cctccattct tccatttaag taagtttaga ggtaagagat tattttaaat tgtttacatt
    41641 atctttgaag tcttttcctc ttacttcaaa actttcatac atatcccaac ttgcacaagc
    41701 tggtgaaaga agcactatat ctccactttt tgaaatttca taagaagtct taactgcttc
    41761 ttccatatct tttactatat gtatgtcatt aaatccttta tttttagcac aattttctat
    41821 atttgatgca gtttctccta ataagaccaa tgatttaaca tatgactttg cagtttcaag
    41881 aagttcatca aaattacttc ccttatccat cccccctgct ataagtatta taggtctatc
    41941 ataagactgt atagctttta tagtggaatc tggattagtt ccctttgaat catttacata
    42001 tattacattg tctaaatttc ttacaaactc ttgtctgtgt tccactcctt taaatgtcat
    42061 aagtacatcc tttgtaactt ctaaatcaat tttgcagaca tatgctattg ctatagctgc
    42121 catacaattt tctaagttat gacctccagg taaacttaca tcatctttat ttagaaattt
    42181 gattttatca tctatatcta ttattatgtc attattttct aaatatactc ctccatttac
    42241 ttttttagtt cttgaaaagt aaattacttt ggcattgcat ttatcagcta aagattttac
    42301 tacctcatca tcatagttta acacacagaa atcctcaaca gtttggttca taaatatatt
    42361 tgcctttgct tctatgtatt tttccatagt atggtgtcta tttaagtggt cctctgtaat
    42421 atttaatatt gcgcttactt taggtctaaa ttcatctata ctctcaagct gaaaactgct
    42481 tagttcagtt actaacacag actcttcact tgaagtttct atagtatcta ttacaggatt
    42541 tcctatatta ccaactacat atgtatctcg ttttgctctt gaaaaaattt ctcctaccaa
    42601 actagttgta gttgtctttc catttgtacc tgtaatccct ataaaaattg gattattcga
    42661 tagtttaaaa gctaattcta cctcaccaat tatatacttg cctgaatttt ttaatttcaa
    42721 tatgaatggt aggtctagtg gtacacctgg agacactaca accatatcta tatcatctac
    42781 atcttctggg tgatgtccta atatgtattt tatgtcattt atagatttca attcatcaag
    42841 tatatttctc aatttatttt catcttttat atcatttacg attatacttg cacccaattt
    42901 atctaaatgt ttaattgtag atataccagt ttttgcaagt cctactaata aaactttttt
    42961 tccttttaag tccatttttc attcccccta gccctaaaat actgctatta tacttatcca
    43021 agctaaaaca actgttataa tccaaaaaat aaatacaact cttgtttctg gccaaccaca
    43081 ctgttcaaag tggtggtgta ttggagccat cttaaagaat ctctttcttg ttgccttaaa
    43141 atatccaact tgaatcaaaa ctgatagagc ctccgcaaaa taaattcctc caattatagg
    43201 tattataagc actgagttag ttagaactga aaatgctaca actgcacctc ctaatgccat
    43261 tgaacctgtg tcgcccataa acactctagc cggatatgaa ttaaatccta agaaacctaa
    43321 acatgctcca acagttgctg ctgctaaaac tgcgacttct gtatttccag caatagaact
    43381 tgcaaatagc ataaagaata cagaaactat taatgttact cctgatgcta atccatctaa
    43441 tccatcagtc aagtttacag catttactat tgctacgatt ataaacatca ttattggtat
    43501 atataatatt ccaacattta tcacaaaatc tgtaaatggt atcataagtt gtgaagcact
    43561 tgatgatgat gtatactgat aaaaagcaac ataaaaagat aatgcaactt gaaggattat
    43621 tttttgatat gcttttagtc caagtgatct ttttagcttt atttttataa aatcatctaa
    43681 aaagccaata aaaccaaaac ctgcaataca tataagacct actgccatat catgactaac
    43741 ttttactctt gtaagtccag ttattagaat tgcaacaatc attataattc cacccatagt
    43801 aggtgttccg tttttagcta gatgtgtttg gggtccatca tctctaactg tctgaccaaa
    43861 tttaaatttt ctaagcattg gtataaatat tggtcctatt ataattacta ttaaaaacgc
    43921 aatcaatgcg gtgtacgtaa gctctgttat tcctaacatc ataaaactcc tctcccttgt
    43981 caattaactc attagtttaa gcttatttat ttagatattc gactattttt tctaatctca
    44041 tgcctcttga gccttttact aaaatagtgt ctcctgtttt tactaattca tttaacttgt
    44101 taaacacatc ttctctattc tcaaagtgat atatattggc tgaattgaat cctaattgtt
    44161 ttgcttcttc tccaataaac actgaatttt cacctatagt tattataata tcagtattat
    44221 tcatagatga ttttccaact aatctatgac catactctga aatttcaccc atttctagta
    44281 tatctccaag tatcgctacc cttctacctt tatatcttcc aagtatcttt aaagcagcat
    44341 ccatagaatc tggactagca ttatatgaat cattaattat tgttaatttt tcatttttta
    44401 ttatgtctag tctcattttt gtccctttaa aattttttaa accttttttt atataatcta
    44461 aagaaatatt tagacacaaa ccaactaata tagcagacat tgcattatat atattatgtt
    44521 ctcctattgt tggtataaat atttcctctt ttttcccatt tattacacat ataaatgtta
    44581 aactatcctc ttccatagta taactttcac aataaatatc attgttttta ttaaagccaa
    44641 atgtttttaa cttatataca tgttcttttt cttttaatgt agataaaaac ttatcatctc
    44701 catttacaat taaagtattt gtttcatcaa agtttgaagt aatctccatc tttgctttca
    44761 aaataccctc ttgtgaaccc agtttttcta catgtgataa tcctatattc gatatgactg
    44821 caattttagg atttactata tccactaaat attttatttc attgaatcca gacataccca
    44881 tctctattac agcacactca tgttctttat ttagattaaa taaagtcaat ggaactccaa
    44941 aatgattatt taagtttttt tcatttttta gtatatttaa ctttgcagat atggcagagt
    45001 aaatcatatc tctagtagta gtttttccca cactacctgt aacacctata aatggaatat
    45061 caaatttttc tttatagtat tttgaaatat ctcctagagc caaagatgta tcttttacct
    45121 ctattaaatt tatatccgaa ctttctaatt ttattccatt actttcattt tttataaaag
    45181 ttttacatcc actatcatat gcaggcttca taaatgtatg cccatctaaa ttttctccaa
    45241 ctatggctac aaatgcattt tgggcacttg cctccctgct atctataact atatcactta
    45301 cacagtcatt ataatctcca tatattaact tcccattagt tgcaagtact aactctttta
    45361 ttgttaagca ctccattatt aaactcctcc tttaaaacct tagctatatt ctcttagcaa
    45421 caaaaggcaa tgtataccgt tatatataca ttgcctacga taactcttaa ctttataatt
    45481 atatactata tttctgtttt tttgaagatg tttatgggta tatgttaatt atctgttact
    45541 ttttagtttt caaaatatag ggttatactt gagtcttcat taacttttac tccaggtttt
    45601 gggaatatat cctttacctt tgtatcttct ggaagttcta tatctgcatc taagtctggt
    45661 tttaacttcg catcctccaa tgcctttaca gcatctccta tttttagatt tcttacatct
    45721 ggcactttaa cttgcttctt ttcatactca gctttttctt cttctttata tactggttta
    45781 actcccaaat attttaaaga gtcattcatt atttctttca ctattggtcc tgctgtagta
    45841 ctaccaaatg cacttactcc tgttggttcg tcaacaatag caagaactac tatttgcggg
    45901 tcatcacaag gtgctattcc aacaaatgaa catatatact ttcctggagc atacttacca
    45961 tctataactt tttgagctgt acctgtttta ccaccaagtc tataccctgg tatatatgct
    46021 atctttcctc caccttcagt tacaactgat tctgcaattt ctaacatttt tttagatgtt
    46081 tctttagata taacacttct tacttttttt ggttttactg tttcagttat atttccttta
    46141 ttgtcagtat aagattttac cactcttggt tgcattaaat ctccaccatt agctattgat
    46201 gatatagctg ttataagttg tattggagtt actgatatag attgaccaaa tgatattgta
    46261 gccaattcaa ctggtcctac atttttttcg ttatacagta ttcccttagc ttctcctggt
    46321 aaatctatac ctgtcttatc cataaggcca aatgattcta tataatcata catttttcca
    46381 acacctaatc tgcttcctaa ttcaacaaat actgggttgc aagagttttg tactgcttgt
    46441 ttaaattctt gtgttccatg aggtctgtaa tgtctccaac atttaatctt tcttcctcca
    46501 acagttacac tacctgtaca tgtgaatttt tctccatctt taattactcc ctcttcaaga
    46561 gcactggaag atgtaataag cttaaatgta gaacctggtt catatgtatc acttactgct
    46621 ggatttctcc acatttgata atagcctttt attttatctt tatcattata tttttcaagt
    46681 tcttcttgat aatatggata tattggcgtt cttgagtcat tagggtcata atctggtttt
    46741 gatgctaaag caagtatatc acctgtttta gggttcatag ctattgcagt aacctttttt
    46801 gcattattta actcataagc tttctgtact gctttttcag tatagtgttg aattacttca
    46861 tctatagaca acacaagacc attaccttgt acaggctcat aatatttttc cattccttgt
    46921 ggtatttctc ttcctgaggc atcagtactt actataagtt ttccaggctt tccttttaac
    46981 tttttatcat attgcatttc tacaccagat atacctgttg catctgaaga agtatgtcct
    47041 aacacatatg gcgcaaaatt cccatatggg taatatcttt gattatcttc tgctacccat
    47101 attccactta atttagcatc tcttatttga cttgccttat catcatctat ccatcttttt
    47161 acttttacaa gagccatatt ttttttgctt attaaagcgt aaatatcttt ataatcttca
    47221 tccaaaatct cagctacctt ttcagctgct tcttttttat cttctacttc cacaggttta
    47281 caccaaacag tatacttagt tacacttact gctaattctt tcatatttct atcatatata
    47341 gttcctcttt tgggttctat tggtatatct cttgtttgtt gttctagtgc ttttgtactc
    47401 aaccaatttc ccttcataag ttgtaggtac ccagtcctaa taacaaggca aaaaaacaat
    47461 gcacatgcta gaataagaac gagtaccagc cttttcttac ttatcctctt tacttttctc
    47521 aaatctattc cccctagtta tccacatcta tatactttat ttgtccatct tttggatagt
    47581 ccatattgag caattcctta gcctttagct caatttcttt tattgatgtt ttttcagttt
    47641 cttttgcctt tagttcctct aatactatct ctttttttct taaatctttt tgtaaataat
    47701 agatatcgta cttcatttcc gagatttttg aataaccaca tagattcaat attattactg
    47761 aaaaaattgc aatcagtaaa atgcatttag ctcctatttt tttcttattt ctctttttat
    47821 aattattctt ttttttattt ttatattcat ttagattatg tattttataa ttttttttca
    47881 aattctcacc ccgatagtat atagtttaaa ttttcctcta tactatattt gttattaatc
    47941 atatttcttc ctctaaaatt tcatcgctaa attaatacac tattacacaa tctaattgta
    48001 tttttttcta tacacaacaa aaacctataa attcacttat acttttatat gaatctatag
    48061 gttagatatt aatttctatt tatttttatc acttctagta tttttagata atttcttcca
    48121 taaatataat atgtaactaa ctatctactc tctgattcct aagttctcca ttatattact
    48181 taataccatc tatatctata tttttatatc taaattttca ttatatatct caataacaaa
    48241 gaacatttct tatagtgtta attgtttttt aattgcttta ccagttcaac aaaatatata
    48301 atacttttta attaattata gtaatcttat tttatatata agattattct ttagccttat
    48361 aactacttat attttttctg ctactcttag cttagcactt cttgaacgtg gatttacttc
    48421 tatttcttcc tcactaggta atataggttt tctagttatt attttcacct cagattcttt
    48481 atcacattgg catataggta aatgttgtgg acatatacaa tctgatgcta aatgcttaaa
    48541 tgcatttttc actattctat cttctaatga atggaatgtt attatacata ttcttccacc
    48601 tttattcatt atagaagaag catcatttat catctttgta attactccaa gttcattatt
    48661 tacttctatt cgtattgcct gaaaagttct tttagctggg tgaggtccat ctattctagc
    48721 tttcttaggg atagcttttt taattatatc tactaatttt cctgtagttt ctattggttt
    48781 gtttgctctt tcttcaacta taaatttagc tatacgctta gcccagttat cttctccata
    48841 atcttttatt atcttagtta attcatcttc tgtataagta tttacaacat catatgcaga
    48901 aaactcacac ctaacatcca ttctcatatc aagtggtgca tcttgcatat aagaaaatcc
    48961 tctatcagct tcatcaagtt gatgagatga aactcctaaa tcagctaata caccatcaat
    49021 tttgtaaact cctatttttt ctaattcctc ttttatattt tcaaaattgc tgtgaacaaa
    49081 cttcactcta ctttcatatt cactcaatct ctcttttgct gtgcttatag catttttatc
    49141 ttggtcaaac cctataaata atcccttatc tgacagtttt tttactattt ctttagaatg
    49201 tcctgctcct cccatagtac agtcaacata cacgccatct ggctttatat ttaaattctc
    49261 tatacactca tttaaaagaa ctgatacatg atgaaattcc atagttacct cccttaaatt
    49321 cactttttaa actattcttc actaatatta tgtttatttt tctttgataa ataaacatgt
    49381 gcaattatgc caccaataac tccaattaga cttataactt gtgccattct aagtggtcct
    49441 aacattaaac tatctgttct taatccctct ataaaaaatc ttcctattga atataaagtt
    49501 atataagtaa ctataacttg accttcatat tttttatttt ttctaaatag taataaaact
    49561 ataaatattc caaaatccca tatggactca tataaaaaag ttggatgtac ctttactcca
    49621 tcaaccatta ttccccaagg taaattggta gcacctccat gtgcttctcc attaataaaa
    49681 tttccccatc ttccaatagc ttgtgctaaa ggcattccaa gtataactgt atcagccatt
    49741 tttaagaagt taatattttt aatcttagtg tatatataac cagctaatat tccaccaatt
    49801 aaccctccat gtatagcaag tccaccacct ctaaaattaa aaatttgaga catattttga
    49861 gcatagtaac tccaattaaa tacaacataa tagattcttg cacagattag tccaactgga
    49921 attgctatta tagctatatt taatacatca tcatctttaa ttcccactct ttttgcttct
    49981 tttattgcta ttaaagttcc taaaatcatt ccacatgcca taagtattcc ataccacatg
    50041 atgtctatgc caaacagtgt aaatgctact ctatccataa cgtcacctct ttgtattaat
    50101 tgaaaatatt tccaaagcaa tatgctataa ttacaattaa ttgtaattat actaaattat
    50161 gataacacat taatgttaat tctacaaaaa atattaaaat ttattctaca aatccctaca
    50221 ctatattata ctaatataat tactataaaa ttttttaaac tgaatctctc atgactaaag
    50281 ttacaagtgt acatagatat tttttaatca aaaagattga tgcatatata catcaacctc
    50341 ttctattcct tatctatagc tcttaaattt ttacctcaat ttatataaat atattttata
    50401 aatttgtttt accaaaataa acatttaaaa acataaataa tacttaatta gttattctta
    50461 ttatgattaa gtttctattt aggttctaca atagaaataa cacaatactc ttctttaaaa
    50521 tgctctttta atctttcttc aacttcctca aaagtaatat ctttaataac atctaaataa
    50581 tccaatagat ttatatcctt aaaaacataa gatataaaac tattacctat aaagtttata
    50641 gaatcaaagc acttaataaa tgaccctatt tttttctttt tagttctctc aaactcttct
    50701 tttgataatc cttctttttt tgatttttct atataatcaa gaattatttc ttttactttt
    50761 ttaggctctt tagaatctcc agctattatg ctaaaagcat aatccacttg agacgaaaat
    50821 ccagctccaa aattttcatt tattaaacct tgcatataca aatcttcata gagcttactt
    50881 ccttttttaa ataacatccc tacaagtata tcagttacaa tctctttacg taaaagttct
    50941 ttccctttta aaccaacatt actatcttta aaacctatgt tgaacatagg catagatata
    51001 gggaattttt ctataacctc tttttctttt acactttctg gttcttctgg ataaaatctt
    51061 tctatactct tagagagttt gtctactttg taattgtttg actttttagt tacatctata
    51121 actttttcta catctaagtc accaacaaca aataaagcca tatttcctgg attatagaaa
    51181 gtattataac atttatatag ctcttcctta gttatcttat atatactatc aacagtacct
    51241 gctatatcaa ttctagcagg ataatttaca tacattgcct tcaagcaatt aaagtataca
    51301 ttccaatcag ggtcatcatt gtacattttt atctcttgtg ctattatacc tttttccttt
    51361 tcaacatttt catctgtaaa ataaggtgtt tgaacatagt caattagatg ttctaaactc
    51421 tcataaaaat tttcagtagc agaaaataag taggctgtca ttgtaaaatt agtaaatgca
    51481 tttgcattta ctcctaattt tgaaaattta tcaaatgcat ctcctccatc aggttgctca
    51541 aacatcttat gctctagaaa atgtgcaata ccttcattca ctctaatttt cttatcttct
    51601 ccaattggta caaattctaa gtcatttgaa ccataattag tagccaaaat agcatacttt
    51661 ttcataaaac cccttttagg cataaaatat acatctaatc cattttgcaa tttctcataa
    51721 taaacttctt ctttcaatat atcattaact attttttcca tagacatctc ctccattaat
    51781 ttctcaagaa gtatacagta tcaagctcta tattttttat agcttcaact atatcttttt
    51841 ttgtaacctt ttctatacta gatattatgt cttgtacttc agaatttgtc tttgccatag
    51901 actgagagaa aacaaaatca gacataccac ctatattatc agttatagat ttcatagaat
    51961 taactaaagc aagtttactg ttttctaatt cttcatcaga tatatcacct gcttttacac
    52021 tttctacttg tttttttatc aattctacag ctttatcata atctttagtt tctataccag
    52081 atgatataaa catgatactt ttatacttct ctattgaaga gaatatatag taacataaac
    52141 tttctttttc tcttacatta acaaataatt tagagtgtgg accaccacct aagacattgc
    52201 tcccaactac taaagcataa tatttatcta tgtctgcata atccacattt gctctataac
    52261 ccataactaa cttaccttga gttatttcca tttgttcatc tataactttt acctcatcca
    52321 cattttttat aaaatctgct cttggtatat ttataatttc ttctctttca aattttagat
    52381 ttttacttat tatatctaca actttatctt catcaaaatt accttctaca actatatcta
    52441 taggtgatgt tttaagtatg tttttataat gttcatataa ctctcttgaa gttatactat
    52501 ctatttcatc ttcataacca aattcactta cactatatct ctctccttta cacatagcct
    52561 caatacattt atcttgcgca tattcctttt tatcatttat tattgattgt atcttttctc
    52621 ttaaattctc tttttcaata tttaaatatt cttctttaaa cccaccatct acaacaagcg
    52681 tattatttat tacttcatta aaaaattcta ctacttcttc aaatatactc tcatctaaat
    52741 acttttcact tatgttaatt actttaaaac tcaatacttg acgttctcca cgttttacag
    52801 catcagctcc catagatgaa ccatataaat catctaattt attggatatt gctctagcac
    52861 taggatattt agcgcttcca cttgctatta ttgatggtat tagagcattt tttgtagttt
    52921 ctttttcatc caatagtctc tgaacatata aacttataag attcgattta aacttttctg
    52981 tttttatcaa agtaagatta atattattac ctaaatttat tattttttta gtattaacca
    53041 tatgtacctc ctatttttat ttaaacatca attttaaaat tgaaatttat ttatttttta
    53101 attatatata ctcacatata aaaaccttct atttaattat atccttttta ttattttcta
    53161 aaagcaatat ttttatttaa attaaatgca aatattattt aaatcaatat gctttaaagt
    53221 ctagtttaca agcttgatat atatgatgta taatcaatat gtatgtctat aattaaaaca
    53281 attttgcaat cctatagatt gattgtttaa agttatataa agaatataaa aaagaataag
    53341 agagaggacg attaatatga aattaggtat agttggtttg ccaaatgtag gtaaaagcac
    53401 actatttaac gcaataactc aagcaggtgc agaatctgca aattaccctt tttgtacaat
    53461 agacccaaat gtgggagttg tatctgttcc agatgaaaga ttaaacaaac tacaagaatt
    53521 atataattct gaaaaaatag ttcctactgc tatagaattt tgtgatatag caggtttagt
    53581 tagaggtgct tctaaaggag aaggtttagg aaataaattc ttatcacata taagagaagt
    53641 tgatgcaata gttcatgttg ttagatgttt tgaggatgaa aatgttgtac atgtagatgg
    53701 ctctgtagac ccacttcgcg atatagaaac tataaactta gaattaattt tctcagatat
    53761 agagattctt gaaagaagaa ttaataaaac tcaaaaagct gctaaggctg ataaaacttt
    53821 aggttctgaa cttgatttat taaaatcaat aatgtctact ttagaagaaa gtaagtgtgt
    53881 aagaactatg gaatttacag aagatgaaca aacattcgta aattcattgg atttacttac
    53941 atctaagcct gtaatatatg cttcaaatgt atcagaagat gatttagctg ataatggaga
    54001 aaataataaa tatgttcaac aagttaaagc atttgcagaa acagaagatg ccgaagttgt
    54061 tgtagtatgt gcacaaatag aagcagaaat ttctgaactt gattctgctg aagaaaagaa
    54121 agagttttta gaaacattag gtcttgaaca atcagggctt gataagctta taaaatcttc
    54181 ttatgcttta cttggtttaa tttcattctt aactgctggt ccaaaagaag ttagagcatg
    54241 gactataaaa gttggaagta aagctcctca ggcaggagga aaaatacatt ctgatataga
    54301 aagaggattt atcagagcag aaacaatagc ctttaatgat ttggttgagc atggtactat
    54361 ggctgctgct aaagaaaaag ggttggttaa attagaaggt aaagaataca tagttaaaga
    54421 tggagatgta atattattta gatttaatgt ttaaaatgat taatcatata cactttgact
    54481 attatatata ataactaaaa aactaag
//
LOCUS       DAEQJM010000021        54183 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.021, whole genome shotgun sequence.
ACCESSION   DAEQJM010000021 DAEQJM010000000
VERSION     DAEQJM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54183
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.021"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            6..82
                     /locus_tag="KRQ43_001598"
     tRNA            6..82
                     /locus_tag="KRQ43_001598"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:40..42,aa:Arg,seq:acg)
     gene            95..170
                     /locus_tag="KRQ43_001599"
     tRNA            95..170
                     /locus_tag="KRQ43_001599"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:128..130,aa:Val,seq:tac)
     gene            246..659
                     /locus_tag="KRQ43_001600"
     CDS             246..659
                     /locus_tag="KRQ43_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741960.1"
                     /translation="MYIVIGNEIVDSEELKIIIDENSKFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLSSLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            968..4399
                     /locus_tag="KRQ43_001601"
     CDS             968..4399
                     /locus_tag="KRQ43_001601"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBH2741961.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            4641..6569
                     /locus_tag="KRQ43_001602"
     CDS             4641..6569
                     /locus_tag="KRQ43_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH2741962.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            7022..7486
                     /locus_tag="KRQ43_001603"
     CDS             7022..7486
                     /locus_tag="KRQ43_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBH2741963.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            7493..7987
                     /locus_tag="KRQ43_001604"
     CDS             7493..7987
                     /locus_tag="KRQ43_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HBH2741964.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            8003..9028
                     /locus_tag="KRQ43_001605"
     CDS             8003..9028
                     /locus_tag="KRQ43_001605"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HBH2741965.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            9015..11462
                     /locus_tag="KRQ43_001606"
     CDS             9015..11462
                     /locus_tag="KRQ43_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBH2741966.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            11642..13015
                     /gene="radA"
                     /locus_tag="KRQ43_001607"
     CDS             11642..13015
                     /gene="radA"
                     /locus_tag="KRQ43_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBH2741967.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDENIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            13018..14088
                     /gene="disA"
                     /locus_tag="KRQ43_001608"
     CDS             13018..14088
                     /gene="disA"
                     /locus_tag="KRQ43_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HBH2741968.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            14177..15271
                     /locus_tag="KRQ43_001609"
     CDS             14177..15271
                     /locus_tag="KRQ43_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBH2741969.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            15400..17577
                     /locus_tag="KRQ43_001610"
     CDS             15400..17577
                     /locus_tag="KRQ43_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741970.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDMSTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSENGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVVFVELGDTYRLDLYKPNLNEKTYESVKDNIEKNIDVYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVLFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(17763..18608)
                     /locus_tag="KRQ43_001611"
     CDS             complement(17763..18608)
                     /locus_tag="KRQ43_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2741971.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCTYQDTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSGKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            18825..19991
                     /locus_tag="KRQ43_001612"
     CDS             18825..19991
                     /locus_tag="KRQ43_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HBH2741972.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNIVLDTHQYLMLAESDGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            20013..21659
                     /locus_tag="KRQ43_001613"
     CDS             20013..21659
                     /locus_tag="KRQ43_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBH2741973.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYIHSSGFDASILHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWRPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNVLGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIADESKDVD"
     gene            21756..23129
                     /locus_tag="KRQ43_001614"
     CDS             21756..23129
                     /locus_tag="KRQ43_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2741974.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNYIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMFFYKLDKEYSTI
                     LNELNTK"
     gene            23574..24527
                     /locus_tag="KRQ43_001615"
     CDS             23574..24527
                     /locus_tag="KRQ43_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBH2741975.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            24565..25527
                     /locus_tag="KRQ43_001616"
     CDS             24565..25527
                     /locus_tag="KRQ43_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HBH2741976.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            25552..26538
                     /locus_tag="KRQ43_001617"
     CDS             25552..26538
                     /locus_tag="KRQ43_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBH2741977.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            26551..27597
                     /locus_tag="KRQ43_001618"
     CDS             26551..27597
                     /locus_tag="KRQ43_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBH2741978.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYSGKIRKCDVEKLTAKETIVSNNTSKYSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            27764..29494
                     /gene="lpdA"
                     /locus_tag="KRQ43_001619"
     CDS             27764..29494
                     /gene="lpdA"
                     /locus_tag="KRQ43_001619"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH2741979.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEVKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEVPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            29912..32860
                     /locus_tag="KRQ43_001620"
     CDS             29912..32860
                     /locus_tag="KRQ43_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2741980.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            32838..33302
                     /locus_tag="KRQ43_001621"
     CDS             32838..33302
                     /locus_tag="KRQ43_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2741981.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            33415..33717
                     /locus_tag="KRQ43_001622"
     CDS             33415..33717
                     /locus_tag="KRQ43_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2741982.1"
                     /translation="MGVTNVTKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            33779..35143
                     /locus_tag="KRQ43_001623"
     CDS             33779..35143
                     /locus_tag="KRQ43_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH2741983.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            35178..35651
                     /locus_tag="KRQ43_001624"
     CDS             35178..35651
                     /locus_tag="KRQ43_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741984.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYINFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGDLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLRFRNKKFENKNI"
     gene            35823..36473
                     /locus_tag="KRQ43_001625"
     CDS             35823..36473
                     /locus_tag="KRQ43_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH2741985.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTFKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            36647..37579
                     /locus_tag="KRQ43_001626"
     CDS             36647..37579
                     /locus_tag="KRQ43_001626"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH2741986.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEDSIFIG
                     KNQNPYQEVHHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYRKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            37853..38566
                     /gene="ispD"
                     /locus_tag="KRQ43_001627"
     CDS             37853..38566
                     /gene="ispD"
                     /locus_tag="KRQ43_001627"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBH2741987.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            38563..39048
                     /locus_tag="KRQ43_001628"
     CDS             38563..39048
                     /locus_tag="KRQ43_001628"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBH2741988.1"
                     /translation="MRIGLGYDVHKLTENRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    39143..39351
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            39415..41130
                     /locus_tag="KRQ43_001629"
     CDS             39415..41130
                     /locus_tag="KRQ43_001629"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH2741989.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDQCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            41252..42697
                     /locus_tag="KRQ43_001630"
     CDS             41252..42697
                     /locus_tag="KRQ43_001630"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH2741990.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKTKGVAVEVDDRDNYT
                     TGWKFNEWEMKGAPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            43137..44618
                     /locus_tag="KRQ43_001631"
     CDS             43137..44618
                     /locus_tag="KRQ43_001631"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBH2741991.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLVEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEITEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            44839..44994
                     /locus_tag="KRQ43_001632"
     CDS             44839..44994
                     /locus_tag="KRQ43_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2741992.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            45139..46536
                     /locus_tag="KRQ43_001633"
     CDS             45139..46536
                     /locus_tag="KRQ43_001633"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBH2741993.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKIFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            46521..46934
                     /locus_tag="KRQ43_001634"
     CDS             46521..46934
                     /locus_tag="KRQ43_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBH2741994.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            47041..47136
                     /locus_tag="KRQ43_001635"
                     /pseudo
     CDS             47041..47136
                     /locus_tag="KRQ43_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452247.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase (FAD)"
     gene            47442..48272
                     /gene="thyA"
                     /locus_tag="KRQ43_001636"
     CDS             47442..48272
                     /gene="thyA"
                     /locus_tag="KRQ43_001636"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003518901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBH2741995.1"
                     /translation="MSLADKIFIDMCNNILENGVSSDGEVVRAKWDDGQPAHTIKKFC
                     VVNRYDLSKEFPILTLRPTNLKAAIDELLWIWQKKSNNINDLNSRIWDSWADETGSIG
                     KAYGYQIGQKHKYKEGEFDQIDRVIYDLKYNPYSRRIITNIYNHNDLNEMNLYPCAYS
                     MTFNVTGNRLNAILNQRSNDILVANNWNVTQYAILVHMLAQISDLEVGELVHVIADAH
                     IYDRHIPLVKELINRESYDAPKLIINPNIKNFYDFRVEDFTLENYKSGPQIKKIPVAI
                     "
     gene            48285..48779
                     /locus_tag="KRQ43_001637"
     CDS             48285..48779
                     /locus_tag="KRQ43_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBH2741996.1"
                     /translation="MKVIVAVDLNWGIGYGGKLLQSIPEDMKFFKEKTVGNVVVMGRE
                     TFKSLPGKKALKDRVNIVLTRSKSFNDDRLIVCNSIDETLKELQKYENDKIFIIGGET
                     VYKQFLPYCNELYVTKIQKTYEADRFFPNIDIMSNWDLIKESEVKEYNNIRYVFSTYI
                     NNSL"
     gene            48806..50182
                     /locus_tag="KRQ43_001638"
     CDS             48806..50182
                     /locus_tag="KRQ43_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBH2741997.1"
                     /translation="MKKDIFVNRVSNALENDRGAVFVGSGISFSSTEVDWFKLLEPLV
                     NELDITLDNKSDDLPMIAQYIVNNYSGNRGPLVNEISKTFNRKFKLNKYHKYLATTKL
                     STIWTTNYDMLLEDAFYDFDTSVKVSDDSITRNRLEYDVEIIKMHGCISRSDWNEIVI
                     TQEDYDDFSINKPAISQRLSEDLINKSFLFIGYSYRDPNIRNIMINARRLSKKHTQQH
                     YIILKKLKDSDSNITQDDVVRQELWCNDLKRLGISTLFIDEYSELEELLREISQKSRG
                     KTVYVTGSHKESNMNARKLGTKLAKHKDITLLSGQSSGIGSEVVAAFTEECIKSKEDI
                     INRMKIFPNPYSADEKYSDDITLIPDLKKCRTKMLNSTQVVVVFSGGIGTEAEIDVAI
                     KQNCNIIPVITCKEDRENPAIKKILNYSDNMKNIEIKDATYYNKIVDEDGVVTMEEIY
                     ICISKIMN"
     gene            50158..51258
                     /locus_tag="KRQ43_001639"
     CDS             50158..51258
                     /locus_tag="KRQ43_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBH2741998.1"
                     /translation="MHIKNNELKHDIIKLKKRNGFIEVGKDKKTLVNCLIGANELEDY
                     KYEIKKIDCILNISEKPDIVSDLSTKRRKISESIWYKIVKDTPFVSATLPIYLVSKNN
                     NKIDSNELLDIIIEQMENGVGMITIHPTANKQIFEDSKNRMVPVTSRGGGMVIQDLIS
                     KNFSEDNVYLKILPEIIKYAQKHNVCISLGATFRSGNIFDSNDRAQITEIKSQIELAK
                     RIYKSNVGVIIESPGHSRPSDIIKISSILKKEGFPIMPLGPIPTDIAIGMDHIAAAIG
                     ATIMGIEGCANIISTVTREEHTGGRPSIESTVESIRTAKIAAHIIDIHQMNDINLDMS
                     VSKSRAKSNTCIFGKDTRYCDRCRELCPLCIR"
     gene            51301..51726
                     /locus_tag="KRQ43_001640"
     CDS             51301..51726
                     /locus_tag="KRQ43_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBH2741999.1"
                     /translation="MHRIASFSQQSQRYVKLEQFEYIIPPEIEKIEKAKELFINSMKK
                     YQEDYDKLVEILFENHYNKLIKGGKNEKTSKRQVEKKAIEDARYVFPNACETKMVFTI
                     NARSLFNFFEHRCYENGSCLEGTMTCGDIVQVRKKFKNL"
     gene            51739..52476
                     /gene="rlmB"
                     /locus_tag="KRQ43_001641"
     CDS             51739..52476
                     /gene="rlmB"
                     /locus_tag="KRQ43_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBH2742000.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            52479..53006
                     /locus_tag="KRQ43_001642"
     CDS             52479..53006
                     /locus_tag="KRQ43_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBH2742001.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            53071..53718
                     /gene="sigH"
                     /locus_tag="KRQ43_001643"
     CDS             53071..53718
                     /gene="sigH"
                     /locus_tag="KRQ43_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HBH2742002.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            53792..>54183
                     /locus_tag="KRQ43_001644"
     CDS             53792..>54183
                     /locus_tag="KRQ43_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBH2742003.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVP"
BASE COUNT        22289 a         5634 c        10132 g        16128 t
ORIGIN      
        1 aaaatgcgct catagctcaa ctggatagag tgtctgacta cgaatcagaa ggttaggggt
       61 tcgagtccct ttgggcgcac catatgaata gcgagggatt atagctcagc tgggagagca
      121 cctgccttac aagcaggggg tcacaggttc gagccctgtt aatcccacca gtgcaaacct
      181 ctagtaaaac tactagaggt tttatttttg attgaaaaag tttttatatt taggaggtaa
      241 gaaatttgta tatagtaata ggaaatgaaa tagttgatag tgaagaactt aaaataatta
      301 tagatgaaaa tagtaaattt aaagttgaaa aagatttaag taaaagcaca aaaagagaag
      361 atgtaatagc atatcagtta agtatagatt taaattacct agattctctt ataaatgagc
      421 aatgtaattt gtccagttta tctgatgaag agaaatttga tgaatatatg actttgtctg
      481 atgaacttgc actggattta gaagagttaa tgccaaaata tacaataata aatgctagag
      541 catataaatt agacgaggta gatggaattg taaaaataat actagctgta gcgtatgcag
      601 atttagggca cttaaaactt tctgatgtag taaagaggct atctagacaa gtagattagg
      661 atatgaatat gaactatatt aaaaaaatgt ataaaatctt acgtaaagat gaaaataatt
      721 atgtaaacat agaaaaaaac agtataaaat caagtcaatt gtagaaattt tcacataaat
      781 tcatctgaaa ttctataaaa aatgccttaa ttttaatgag gtaaatcgag tttacacagt
      841 ctaaaaatta cttatattta taaatttatc ttattaatta aggaactttc ttaaacatct
      901 tcaaaaataa agtattttag tctataatct ttaatattac acaaacaata aaggagaaga
      961 atagagtatg cttaaaaagt ttaataaaat actagtggct aatagaggcg aaatagctat
     1021 aagaatattt agagcctgtt cagaattggg gataaaaagt gttggtatat acagtaagga
     1081 agataagtat ggattgttta gaacaaaagc agatgaatca tatttgatag gagaaggtaa
     1141 agggccaata gatgcatatt tagatatgga tggaataata gacctagcaa agagaaaaaa
     1201 agttgatgct atacatccag gatatggttt tctagcggag aatgcagaat ttgctcgtaa
     1261 atgtgaagag aatggaatta cttttatagg accatcatct aaggtaatga atatgatggg
     1321 ggataagatt aactctaaaa aaatcgcaaa agaagttaat gttcaaacta taccaggagt
     1381 agaaaaagca ataagaagta ctgaagaagc aaaggaagtt gcaaacaaaa taggatatcc
     1441 tgttatgata aaagcatcta atggcggtgg cggtagaggt atgagaattg tacatcgcga
     1501 agaagactta gaacttgaat atgaaactgc ttgtagtgaa tcaagaaaag cttttggaga
     1561 agatattata tttatagaaa aatatatagc tgatccaaaa catatagaag ttcaaatatt
     1621 aggtgataat tatggaaata tagttcactt atatgaaaga gattgttcag ttcaaagaag
     1681 acatcaaaaa ataatagaat atgcaccagc tttttcgtta gatgataaag taagaaaaga
     1741 gatatgtgaa gatgcagtta agttatcaaa acatgtgggt tattctaatg cgggaacatt
     1801 agaattttta gtagatgcaa atggtgggca ttattttata gagatgaaca caagagtaca
     1861 ggttgaacat actgtaacag agatggttac aggaatagat atagttcaaa gtcaaatact
     1921 aatagcccaa ggttacagct tagatagtga agaaattaat ataaaatcac aagatgatgt
     1981 ggaaataaga ggttactcta tccaatgtag aataactaca gaagacccta agaataaatt
     2041 catgcctgat acaggtaaaa ttcaagttta tagaactggt tcaggatttg gtataagact
     2101 agatggagga aatggattta caggggcaaa cataagtcct cattatgata gtttattggt
     2161 taagacaata tcttgggata gaacattcca aggagcaata aataaaacta taagatctat
     2221 aaaagaactt agagttagag gtgttaaaac taatgtagga ttcctagtta atgttttaaa
     2281 taatcctata ttctcaaatg gtaaatgtag tactaagttt atagatgaaa atccagattt
     2341 atttgaaata acagaaagta aagacagagg aacaaaatta cttcaattta taggagatgt
     2401 aattgtaaat gataatgctt gtaaagaaaa accactattt gatgcattac atgacccaag
     2461 aatggataag gatggttcaa aatcagaagg aagtaaaata cttttcgata agttaggtaa
     2521 atctgcatat atagaaaaga taaaaaatga taagaaatta ctattaacag atacaacaat
     2581 gagagatgca catcaatcat tattagcaac aagaataaga acatatgact tattaaaagc
     2641 tgctaagcca acagaaaaat atcaaaagga tttattctca cttgaaatgt ggggaggagc
     2701 tacttatgat gttgcatata gatttttaaa agaatctcct tggcgtagat tacaaaagct
     2761 aagagaagaa ataccaagca taatgttcca aatgttgctt agagcatcaa atggagttgg
     2821 atataaaaac tatccagata atgtaataga agaatttaca aaagaatctg ctagacaagg
     2881 tatagatgta tttagaatat ttgattcatt aaactgggtt gaaaatatga aaccatctat
     2941 taatacagct ttagaaactg gaaaaattgt tgaagcaact atgtgttata caggtgatat
     3001 actagataag actaaaacta aatacaatct agaatattat attaaaatgg cacaagaatt
     3061 agaaagcttg ggagcagata taatagcaat aaaagatatg tcaggtcttc ttaaaccata
     3121 ttcagcttac acactagtta aagagttaaa gaaaaatgta aaagcaccaa tacatttaca
     3181 cactcatgat acaagtggaa atggtgtagc aacttgttta atggcgtcag aagctggagt
     3241 agacataatt gatgctgcat tagaatctat ggcaggactt acaagtcagc catcgcttaa
     3301 tgctatagta gaggcactta agaatacaga gagagataca ggaatagatt tatttggata
     3361 tgatgagtta ggaaaatatt ataaggattt aagaaaagtt tataataaat ttgaaagtga
     3421 tttaactaat tcttgtgcag aaatatataa ttttgaaata ccaggaggcc aatatacaaa
     3481 cttaaaacct caagctgata gtttaggatt agttaataga tttgatgaag ttaaagaaaa
     3541 atataaagaa gctaatgaag ttgtaggaga tataataaaa gtaactccat cttcaaaagt
     3601 tgtaggagac ttagctatct ttatgactaa aaataaatta gataaagaca atataataga
     3661 agaaggtaaa aatttatcat tcccagattc tgttgtggat tactgtaaag gtatgattgg
     3721 tcaaccagaa ggtggaatac caaaagattt acaagaggta gttctaaaag gtgaagaagc
     3781 tataacagta agaccaggtt cattattacc agcagaagat tttgatgaaa tagctaaata
     3841 tctaaatgaa aagtatgata taaatgctaa tataagaaat gttataagtt atgctttata
     3901 tccaaaagta tatgaagatt atatcaaaca tctacaacat tataatgata tatctaaact
     3961 tgaaagtgat gtattcttct atggattaaa taaaaatgaa gaatgtgaag tagaaataga
     4021 agaaggtaag gtattaacaa taagattagt tgaaattggt gaagttaagg aaaatggatt
     4081 tagaactata ggatttgagt taaatggaat ggttagagaa gtagaaataa aagataagaa
     4141 tttctctgga aaaattaata atgttgaaaa agctgatatg aatgaccctc ttcaaattgg
     4201 agcaagcata ccaggaaaag ttataaaaat aatggttaaa gaagaagatg aagtaaaagc
     4261 aaatcaacca ttaatcgtta tagaggctat gaagatggaa actataatag ttgctaagac
     4321 tgatggagta attaagtcaa tcaaagtaaa agaagatgat atggttgaag ataaacaatt
     4381 attaatgata atgaagtaat ttaattaaaa taaattaaaa agcactctga aatgtttaat
     4441 aaaaaatgtt ttagagtgtt tttatttatt ttaattaaat atttgttaaa aaaaagagga
     4501 caattacctc cagatgtaga aataaagcta gtaaggaaaa tgttatctaa aaattctaaa
     4561 tatagtaaat attttccata atatttctta ggaaataaca gcaaagataa aatacataaa
     4621 tttaaaaggt gggtgcttat atgaaggttt atgatagtaa aatgttgaga aatgtagcag
     4681 tattaggaca tagcggatgt ggaaaaacaa atctaatcga aactatagct tacacagcaa
     4741 acactaataa gatacctaaa ttaacagaca aggtaaatat gacttatagc atgggattaa
     4801 tacctataga gtataatgat tataagttta acttattgga taccccagga tattttgact
     4861 ttagcggaga cgttgtgtca tctcttagag caagtgatgc agcaataata gtaatagatg
     4921 caacagcgcc tattcaagtt ggtacagaga aatcattaga actaactgag agtattccta
     4981 agataatgtt tataaataaa atagataatg aaaaggcaag atacaaagat gcaatagcaa
     5041 tgttaagaga aaaatacaat aataagatag ttcctatgat aagtcctata tacaaagata
     5101 aaaactttgt aaagttacat aatgtttttg aaaacataga tgatttagaa ggtgaattta
     5161 aggaacaagc tatgagtgtt aaagaagcat taatggaact tatagcagaa actgatgacc
     5221 aaatattaga taaatatttt aatggagaag aactaactac ggaagagata caaaaaggta
     5281 ttattatagg tatacaaaga ggtgatatta tacctgtaat atgtggttca actataaata
     5341 atataggcac aaaggaaata ttagatacaa tatcaagtta tttagaacct atctttacag
     5401 aggaaagcaa accatttagg ggattagtat ttaaaactat ggttgaccca tttgttggaa
     5461 agatgtcata tataaagatt actgagggtg tactttctaa ggataaagat gtttttaata
     5521 taaataaaaa tgtaaaagaa aaaatagcta atatatatac attgagaaat agtgaattag
     5581 tagaaataga aaaagctaaa gctggtgata tagtagttat aactaaagtt aattctctaa
     5641 aaacaggaga cactatatct gcagataaag atgcagaagc tttagaaaag atagattttc
     5701 ctaaaccaca aatatattat gcagtaactc ctaagaataa aggtgatgaa gaaaaagtag
     5761 catctgtatt aaataaacta gtagaagagg accctacatt acattggtat agaaatacag
     5821 agacaaaaca agcactttta ggaggtcaag gagaacttca tataaaaaca attaaaaata
     5881 aaatgaaaga taagtttggt gttgatgttg aattgaatga ccttaaagtt ccttatagag
     5941 aaactataaa aggaacagcc gatgtacaag gaaaacataa aaagcaatca ggtggtcatg
     6001 gtcaatatgg agacgtaaaa ataagatttg aaagatgtga atctgatttt gaatttacag
     6061 aagaaatatt tggtggttct gtaccaaaac aatatatacc agcagttgaa aaaggtctaa
     6121 aagactctat gcaaaaaggt atattagcag gttatcctgt tacaaacata aaagctacgc
     6181 tttatgatgg ttcataccat gatgtagact cttctgaaat ggcctttaag atggcagcaa
     6241 gtgcagcctt taaaaaaggt atggaagaag cgcacccaat actactagaa cctataatga
     6301 aacttaagat aactgttcca gaagaatata tgggagatgt catgggtgat ataaataaga
     6361 gaagaggaaa aatatttgga atggaaccag atgacaaagg gaaacaaata atatttgcag
     6421 aagctccaca agcagagaca tttaaatatg caatagattt aagagcaatg acacaaggta
     6481 gaggatactt tgaaatggaa ttagagagat atggagaggt tccatcacag tttgcagaaa
     6541 aaataattgg gttagctact gcaaagtaat gaacaaaata aatagaaaaa taattaatat
     6601 atattattaa aaatattttt agggttttaa ctaggtatag gtttatgtta ggtaaactta
     6661 tacctagttt ttatacattt ttgatgaata aaaaaatata taatactttc ttaaatgttt
     6721 taataaaaag aaagtatttt tttattatta tttttacaaa tgtttagtaa taaagatgag
     6781 aaggtatatt taaaatataa agtatttaaa gttctgaaat ctaatcatga agcaaaaaat
     6841 tagcatttgg ttatcaataa atataataaa taaaaactca taattaatga aagaataaat
     6901 tcatatctaa atttctataa aaaatttaaa tttatacaat ttagggcttt aaaaatttaa
     6961 ataataggtg taaaataata gtcaaagaaa gtcaaaaata aaaaggtgtg tggtgatatt
     7021 aatggcaact atgacagata taattgaaaa atttattaaa gatttgatgg aagaagataa
     7081 tagcatacaa attcaaagaa atgaactagc aaacttgttt agttgtgcac catcacaaat
     7141 aaattatgtc ttaacaacaa gatttacaat agatagagga tattacattg aaagtaaaaa
     7201 aggtggcgga ggatatgttc aaatagaaaa aatacgaaaa agtaaagatg gacatattag
     7261 agaactacta aatgaaaaaa taggaagtca gatatcctat aaaaaagcaa aggaattatt
     7321 agaaggttta aaagagtcgg atttgattaa cgaaagagaa ttaaaattaa tattatatgc
     7381 aatagatgat aaatcattgt gtatgccaat atatgaatta aaagagaagg taaggtctaa
     7441 tattttaaag aatataataa taggattatt tagtatagag gagtgataat ttatgctatg
     7501 tcaaaaatgc aataagaata aagcatctgt atattataat aagatagtca atggagaaaa
     7561 aacagagatg tatttatgta gtgagtgtgc aaaagagaat acagaaatga attttaactt
     7621 agatatgcct ttttcaatga tggatatatt ttctaattta ggttttcaac ctaaaaaaga
     7681 acttgaggaa aagctagttt gtcctaaatg caatacaaca tatagtgagt ttaagaataa
     7741 tgggagattt ggatgtagtg aatgttataa tgcatttagt agtcaagtaa atccaatgct
     7801 tcaaaatata catgggcata tagaacatac aggaaaagca cctaaaaaat ctttttataa
     7861 gataagtgta gaaaatgaga ttaaagaact aaaagaagat ttagatagag ctataaaaaa
     7921 tgaagagtat gaattagcag ctcaatttag agataaaatt aaatatttaa aaggttctat
     7981 tgactaagat tggagtgata ttatgaaaga gaacatagtc atgaaatcaa gagttaggct
     8041 agctagaaat ttaaataact atccatttcc aaataaatta gataaagaat gtgccatgga
     8101 aataatagaa aaagtaaaaa atgcgtttat taattctaac ttagaacaaa aagaagaatt
     8161 tgatttctat aaaattgaag atttagacca atctaaaaaa atgcttatgg ttgaagaaca
     8221 tataataagc ccagatttag cagaaaatga taaaagtgca gttatagtaa aaaaagataa
     8281 aactataagc ataatgataa atgaagaaga ccatataagg atacaaacta tatgtgatga
     8341 tttaaactta gaatatgcat atagtgtagc aaatgaaata gatgatttgt tagaatcaag
     8401 tttagaatat gcctttaaca caaagctagg ttatctaaca tcttgtccaa ctaatacagg
     8461 aacaggaatg agagcttctg taatgatgca tttaccagca ttaagtcaac taggctatat
     8521 ggatgaactt tataaaattt catcacaaat aggtatagca attagaggga tatatggaga
     8581 acgaacagaa gcattgggaa atatatatca aatatctaat caacttacac ttggaagaac
     8641 agagtctaat attatagaaa atgtaagtgg acttacaaaa gatgcaattt caaaagaaat
     8701 aaaagctaga gaaatattgc aaaaaaaatt aggtataaaa ctagaagata aaatatttag
     8761 atcgataggg acacttgaaa attcaagagt aatgagtagc gcagaggcaa tgagccatct
     8821 atcaaatata aaaatgggaa tagaaatgaa ctatatagat aaactagatt taagggctat
     8881 agaacaactt atgataggta tacaaccagc gcatcagtca ataatgtata agagtgatga
     8941 tgttgagaat agagatataa atagagcaac atatattaga gaaactttgg aaaaattaag
     9001 aggagggatg aattgtgaac ttcaatagat ttacacaaag agctaaaaag gcaattgatt
     9061 tagcgtttga atctgctaaa agtctaggac acaatattgt tggaagtgaa catatacttt
     9121 taggtctttt aagagaagaa gaaggtatag ctgctaaagt tctaagtaaa gttggattta
     9181 cagaagctta tttagaaggc aaaatagttg atatggaagg taagggagaa gaaatctcag
     9241 aagatatagt attaagtcca aggagtaaac aaatacttga attatcagga atgtttgcaa
     9301 ataaattaaa aacaaattat attgggactg agcatatatt attagcaatt attcaagaag
     9361 gtgaaggaat agctaataag attttaaatt atgctggagt aaatgatagg actttagccc
     9421 aattaacaat tgatatgatg ggtattagtg ataaaaatca atacaaagca gagaatagtt
     9481 acacgggcaa ccagaatcaa gcagaatcta aagtacttga taagtatgga agaaatctta
     9541 cactatatgc aaaacagaat aaaatagacc ctgtaatagg tagagaaaaa gaaatacaaa
     9601 gagtaataca aatattaagt agaagaacta aaaacaatcc agtgttgata ggagacccag
     9661 gtgtagggaa aacagccata gctgaaggtc tggctacaaa tatagcctta ggaaatgttc
     9721 cagaaacact aaaaaacaaa actttatact ctttagagat gggttcatta ttggctgggg
     9781 ctaagtatag aggagaattt gaagaaagaa ttaaagaagt tgtagatgaa gttgttaaaa
     9841 atggaaacat aatcttattt atagatgaga tgcacacaat aataggggct gggtctactg
     9901 gagaaggctc tatagatgct tcaaatatat taaagccagc cttggcaaga ggagaaatac
     9961 aagttatagg tgcaactaca attgatgaat atagaaagca tgttgaaaaa gattctgctc
    10021 tagaaagaag attccaacca gttatggtag atgaaccaac taaagaggac tcaataaaaa
    10081 tattagaagg attaagagat aaatatgaag ctcatcataa agttaaaata actgatgatg
    10141 ctataaaggc agctgtagaa ttatcaacta gatatatatc agacagatat ctgccagata
    10201 aagctataga cttgattgat gaagctgcat caaaagtaag attaaaagaa aatacacctc
    10261 cttcagaaat aaaaaaatta gaactagaaa tagaaaatat agataaagaa aaagaagaag
    10321 cagtaagatg tcaagacttt gagaaagcag ccaaaataag agatgaacaa ggtctactta
    10381 aaaaacaatt agaagatgtt agagaaagat ggaacaagtc atctaaacat tcagatttag
    10441 ttgatggaga agttattgct gaagtagtgg gcttatggac aggaatacca gttaataaaa
    10501 ttcttgaaga agaggctgat agacttttga gacttgagga aatactgcac aatagagtta
    10561 taggtcaaga acaagcagta aaatctattt caaaggcaat cagaaggtca agagcaggtc
    10621 ttaaagaccc taatagacca attggttcat ttttattttt aggtccaaca ggagtaggta
    10681 aaacagaatt atctaaggca ttagcagaag tgcaatttgg agatgaaaat caaataatta
    10741 gaatagatat gtctgaatat atggaaaaac atgctgtgtc aagaatgata ggttcacctc
    10801 caggttatgt aggtcatgat gaaggtggtc aattaactga aaaagtaaga agaaatccat
    10861 attcagttat cttatttgat gagatagaaa aagctcatcc agatgtattt aatattctgt
    10921 tacaaattct agatgatggt agactaactg attcaaaagg aagaactgta gattttaaga
    10981 atactattgt aataatgaca tcaaatgttg gagcatctac aattggtaga caaaaaactt
    11041 taggatttag tatagctaaa ggagacgaag aagaaaaatc tcaatatgaa aaaatgaaag
    11101 aaaatataat gggtgaatta aaacaaagat tcagaccaga gtttttaaac agaatagatg
    11161 atataattgt tttccactca ctaaatgaaa atcatatatc aaaaatagta cttttaatgg
    11221 cagcgaaact acaagagaga ttaaaagaaa tggatataaa attagaaatg agtgatgagg
    11281 ctgttaaatt aatttctaaa tctggatttg acttagaata tggagcaaga cctcttaaaa
    11341 gagctttaca aaaagagttg gaagatgagc tatctgaagc aatcttaaaa ggtaatgtga
    11401 aaaagggaag taatgtagta gcaaaagtca aagatgaaaa aatagttttt gaaactaaat
    11461 aatttaatag agttgcattt taaaatattg caaatataag ttttataatc taaacaaaat
    11521 tttaagggca atgaatctat aataattcat tgtccttaat tattttattt aatctttaca
    11581 tattgtcttt cagatatgct aaaattatag tatagaataa aaaattaagg atgataaaag
    11641 tatggcaaaa ataaaaacaa aatatgtatg tcaatcttgt ggatatgaaa cagctaaatg
    11701 gcttggtaaa tgtccagaat gtacaaaatg gaatacattt gtagaagaaa tagaccaaaa
    11761 aagcaccaaa aaagaggtct ttataataga taaatcttca tctaaaccag tcagtataaa
    11821 ctcaatagaa agtaaagaag aagagaggtt tacaacagat ataaatgaat tagatagagt
    11881 gcttggagga ggtatagtta aaggctcttt agtgcttgtt ggtggtgacc ctggtatagg
    11941 taaatcaaca cttttaatcc aagtatctag taatgttgcc aatttaggaa aaactgtttt
    12001 atatataact ggagaagaat cagaatctca aataaaaatg agagctaaaa gattaggtat
    12061 taactcagaa aatttatata tatttgctga aaataattta agtataattg aatcttattt
    12121 agaaagtgta aatccagaat taataattct agactcaatt caaactgtct tcagtccaga
    12181 aatatcctcg gcaccaggaa ctgtcagcca aattaaagaa ggtacttcaa aattcatgaa
    12241 aatttctaaa aaaatgggaa tttcaacgtt catagttggg catgttacaa aagaaggttc
    12301 actagcagga ccaaaattat tagagcatat ggttgatact gttctatatt ttgaaggaga
    12361 aagatataat acttatagat tagtaagagc tgttaaaaat cgatttggtt caactaatga
    12421 acttggagta tttgaaatga gggatttagg attagtagaa cttgataatc catctaaaat
    12481 tttaatctct gaaaaaccaa aagatgtagc aggttcagta ataatatcta ctgtagaagg
    12541 tacgagacca atgttacttg aattgcaagc attagtttct cctacaagtt ttggtatacc
    12601 aaaaagaaca tctacaggag tcgattacaa tagagtaggt atgttattag cagtattaga
    12661 aaaacgtgtt ggtttgcaaa tacaaaatca agatgtctat ataaacatag ttggaggaat
    12721 aaagataaat gaaccctcaa ttgatttagg gatagccatt tctgtagcat ctagttttag
    12781 aaatataccg atagatgaaa atatagctgt tacaggagaa gtgggactta caggagaagt
    12841 tagagcagta agctttatag aaaagagaat agctgagtgt aaaaaacttg gatttaaaaa
    12901 gatagtagtt cctagaagta attatgatgt tgtaaaagag accaaaggca tagaaatatg
    12961 gccagtagat aacttaagac aagctataaa tatagtactt gggaggaatc aataaatatg
    13021 gagaattttc tagataataa aaatatgcta tatgcattaa aaatgatatc tcctggaact
    13081 ccacttagat taggtctaaa caatgtacta agagctaaga ctggtggatt aattgtaatt
    13141 gcaacaaacg aagatgtaat gaaaatagta gatggaggat ttgctataaa tgcagaatat
    13201 tcaccatcat atctatatga attagctaaa atggatggag ctatagtttt aagtggtgat
    13261 gtaaagaaaa tattatttgc taatgcacaa cttatacctg actattttat agaaacatca
    13321 gagacaggaa caagacatag aacagcagaa agagtagcaa aacaaactgg tgctatagtc
    13381 ataggaattt cacaaagaag aaatgttata acagtttata gaggaaatga gaagtatgta
    13441 gtcgaagata tatctaagat atttactaag gcaaatcagg ctatacaaac tctggaaaaa
    13501 tataagacag tattggacca agctgtaaca aatttaaatg ccttagagtt taatgatttg
    13561 gtaactattt atgatgttgc attagtcatg caaaagatgg aaatggtaat gagagttaca
    13621 agtataattg aaaaatatgt gatagaattg ggtgatgaag gaactttagt aagtatgcaa
    13681 ttagaagaat taatgggtac aaccagaata gaccagaaat taatattcaa agattataat
    13741 aaagaaaaca cagaaataaa agaacttatg aaaaaggtca aaaatttaaa ttcagaagaa
    13801 ctaatagaat tggtcaatat ggcaaaacta ttagggtata gtggtttttc agaaagtatg
    13861 gatatgccta taaaaacaag aggttatagg attcttagca aaatacatag actaccaaca
    13921 gcaataatag aaaacttagt aaattatttt gaaaactttc aacaaatttt agatgcatct
    13981 attgaagaat tagatgaggt tgaaggaata ggtgaaataa gagcaacata tataaaaaat
    14041 ggactcataa aaatgaaaca attagtctta ttagatagac acatatgatg aattttaaat
    14101 gaattttact acttttttct tgaatataat atacactttg gtctataata gataagtata
    14161 actagggggt gaagcattga taaggaaagt aacaagaata ttgtttattt tacttggatt
    14221 tacaataggt ataacaacct atttaacatt aatgaaagat tttgaaatat taacatttgg
    14281 aaaagaaaca tatggttata tcgcagctgt agtagcaggt ataataatag ccattttagg
    14341 atatcttata gaaccatggg ttgtaaataa agtaaaagaa attgctaaaa tagtggataa
    14401 agaattgtca aaatatcctc agactgatat attgttaggg tctatgggtc ttatagtagg
    14461 atttgttatt gcgtatttat taagtggatt agtaaataga ataccaatag taggtggaat
    14521 actatcctta ctattatatt tattcctagg atatcttgga atgaaagttg cgcttaaaag
    14581 taaaaatgat ttatttaata ttggaaaact aggaagatta gcaaatccta ttaaggataa
    14641 agataaggat aaagaaaata aaaaagaagt aaaagccatt cctccaaaag tattagatac
    14701 aagtgtaata attgatggaa gaatagctga tatttgtaag actgggttta tagaaggaaa
    14761 acttattatt cctgcttttg ttttggagga actaagacat attgcagatt cttcagatga
    14821 tttaaaaaga gtaagaggta gaagaggtct ggatatatta aatataattc agaaagaatt
    14881 aaatatagaa gttgaaataa gtgagagaga ctttgatgat atagcagaag ttgatagtaa
    14941 attattaaag cttgctcagg ttttaaatgg aaaagttgtt acaaatgatt ataacttaaa
    15001 taaagttgct caattccaag gtgttgaagt attaaatata aatgagttag ctaatgctat
    15061 aaaaccagtt gctataccag gtgaagatat ggttgttcaa gtggttaaag aaggaaaaga
    15121 ggctcaacaa ggtgttgcat atctagatga tggaactatg atagttgttg atggaggaag
    15181 aaaatatatg aatgagacta taaaagtact cgttacttct gttcttcaaa ctcctgcagg
    15241 tagaatgata tttgcaaaac ctaaaaatta atatgttcaa agaaacctat aatttgggct
    15301 gtttatttta aatagatggt ccaaatttat ttatttataa cgataatgtt taatgtattc
    15361 ttaaagatgg ggatttaaat cagaaagcag ggagaattta tgagaaaaaa gattatatct
    15421 ttcttagcaa catttatcat aatattaaca tcagcaagtc agtatagttt tgcagatgat
    15481 atgtcaacac gtggaaaagt aatatttata gatatgaata gaactagtat gagtaatatg
    15541 ttaagaataa aatcattaag agaagaacta gacaatagag ggtatattgg cttgatgaat
    15601 ataagaggcg ataaaggaag tgatgataga aggtcatatg ctagtatggg tgctggtggt
    15661 agagctaatg tggctaatga agaagatatt aattttgaaa gctcgagtaa ggatagaaat
    15721 atagtttttg aatcagctac aggaaaaagt gcaaaaggta taaataattt aactataaat
    15781 aagtctataa atgaaaattt aaactttgga gagtatggtt ctgtattagg gtcattagga
    15841 caaagtttat ctgagaatgg attaaaagca tctgtattgg gtaattcaga tataattgaa
    15901 aatggtcaac ttataaaaaa tagaaactta tgtctaactg caatggatga atatggaaga
    15961 atacctaatg gaaatgtaga tactataaat aaaaaagact tatctatgcc ttatggaata
    16021 tcaactgatt atgataaatt gattgtagag accaaagaag cttacaaaaa taatgatgtg
    16081 gtttttgtgg agcttggaga cacatataga ttagatttat ataaaccaaa tttaaatgaa
    16141 aaaacatatg agagtgtgaa agataacata gaaaaaaata tagatgtata tttaaaaaat
    16201 atattttcta tggttgaaga aaatgacact gtctacatag caagtgcatt tccaagtgat
    16261 ttagattata aaaataaaag aagactttct ccaataataa aattaaatgg agaagggaaa
    16321 ggtatattat catcttcaac tactagaaga gaaggtattg taacaaattt agatgttggg
    16381 gttgaaatat tagacaactt taatataaaa aatcaaaata tggttggaag aaaatatgaa
    16441 cttattaaca gagatgataa taaagaattt ttgatggatg aatatcaaaa gatagtatct
    16501 atttcaagca taaggtctac aatactgaat ggttttgtaa gtatagtttt cttgtcatgg
    16561 atagttgcta tgattgcaat tttatttaga aagcatatat caaaaaatta taaagaaaca
    16621 acatttttta tattaaagga acttttaaaa ataggaatag taatgccact gtcatttatg
    16681 ataacaccaa taatgaattt caaaacacca ttagcaatat ctttaggaat aattataata
    16741 acacttacta tatatcttat aagtaaagtt ttaataaaga atgatttaaa aaacatgctg
    16801 ttttttactg gattaaccat agtaattatg gttattgatg ctgggtttgg ctcatattta
    16861 atgaaaagca atgttatgag ttatgactgt ataattggag ctagatatta tggagtggga
    16921 aatgagtatc aaggtgtggc aatcggtagt gcaatattta catttgcaat tttacttaca
    16981 tataaaaata taccaaagtg gtctataata gttttttctt tggttatctt aattacaagt
    17041 gcatctccaa ttatgggagc aaatgttgga agtgctattt ctgaatgtgt tgcattttta
    17101 ctatttatac tattgatata taatgtgaag atagacttca aaaaaattgt attattaggt
    17161 atagcagtat tatttgtatt aggagttttt gtagcaatag atatgatttt gggaagtaat
    17221 tcacatttag gtatgtttgt aaaagaaatt tactttaatg gaccaggaga aataatacaa
    17281 acatttagta gaaagataga gatgaattta aagctagctc aaaccagtgc atgggtaaat
    17341 atactgttaa ctggaatagg tgtaatttta gttcttatga ttaatcagat tagatacttt
    17401 aagcaactga tggatgagta tccaattgta tttaaaggat ttatagcatc aatagcagga
    17461 tgtttagtaa ctcttttagt gaatgactct gggattgtgt catcagctac agcctttatt
    17521 tatgtaattg tacctatgat aacattaagt ataaatctca cagcattaaa agaataagta
    17581 ctgtatgaat aatatgtaaa tatgaacaca ttaatttaac ttctttattt acaaaataaa
    17641 gaagaaagtt tataaaaaat aaattataat aaaaaagagt ttacctcaaa attgattatt
    17701 ctaatcaaat tttaaggtaa acttttttta ttataaagat aaataacata taacctcata
    17761 ttttaggtag atttttttct tatatgttta ggagtgcatt taaatttttc cttaaaaatt
    17821 ctgtaaaata attttgtatt agtaaatcca tgagcttcta atatactgca taaggtatca
    17881 tttgtgttaa ttaagtcttt ataaatatga gaaatacgca catcatttaa atactctaag
    17941 taagtttgtc ccatatactg tttaaatttt ctacaaaaat attctggctg taagtgtgct
    18001 accttagcga ttttgttaat agaaataggc attttgtaat taatctttgt atattctaaa
    18061 actggttcaa attttgacaa atcaagtact gtttttttca tatttttatt acctacagat
    18121 attttaaagt ttgtatataa ttcaaataaa agttcaaata ataagcttgt aaagagcaga
    18181 ttagctgcag gaggagagct aagtttaatt tctctcatgt tttctaatat aagtttaact
    18241 ttacctgaat tttttttata gttattgtca ttggcattaa ccttaaagtc aaaatagcaa
    18301 tttttaaaat cagggatata tttgtttaga aaagacaatg gtacttgcaa taatatagag
    18361 gtatcttgat aagtacatct agttgagtga ataattccag aattaatgaa catacactca
    18421 ttagctttta aattataagt gtaaccctcc atgttaattt gtaaatcacc agaagttata
    18481 taaattattt ctaatgagtt atgccaatga tttgctacat aactaccact atcatcaaat
    18541 agtttgaaat taacatctaa attatcaata ggttcaatta tttcatgtga aaaattattt
    18601 ctgttcataa taatatcctc cttataattt taaattataa atagtaaatt tataatgttc
    18661 aatattaaaa agataatata gactaataaa ttagataata aacatactta agaaaacgga
    18721 taaaatcaaa tataataact gtatattaaa ataacttaaa aaaattattt tattataagt
    18781 gcaaaatata cctatttaaa taagataaga ggggaggatt ttatgtgtat ataaaaggtg
    18841 taaatttagg aggttggtta gttttagaaa aatggatgac ctcaagttta tttgaaggca
    18901 cagaagctga agatgaatac tatttaccaa gacagctttc aagagaggca tatgaatcta
    18961 gaattaagac tcatcgtagt gaatacatca cagagagaga ttttgcaacg attaaatcta
    19021 tgggatttaa ttcagttcgt ataccagtac catactttat ttttggagat tgtgaaccat
    19081 tcataggatg tgttaaagaa cttgataaag catttgcttg ggcagataag tatgggctta
    19141 gtatattgat agacttacat acagttccag gaagccaaaa tggatttgat aatggaggaa
    19201 tatcaggtat atgtagctgg tcacaaaatc cagaatatgt agcgtttaca ttaaatgtat
    19261 tagaaagact tgcaaaacgt tatgggatga gacatgaatt gtatggaatc caaattttaa
    19321 atgagcctat aacagaaaga atgtggaaca taatgaatgt tccaaatcgg tttaaggctg
    19381 tagataagga gatggcaagg gggagtaaac ctaattcatt agagttttta cgtgattttt
    19441 atataaaagc atataaggta atgcgtcctt atatgagaga ggaaaacgtt atagtgtttc
    19501 atgatgcatt tgaattaaaa gcatggaaag actttatgag agaggaagaa tttaaaaata
    19561 ttgttctaga tacacaccaa tatttgatgt tagctgaatc agatggatgt gaacaaagta
    19621 ttgatagcta tctcaaatat attagagaaa attatgctaa agatatttta caaatgcaaa
    19681 aatattttcc tgttatatgt ggggagtgga gcttatttaa ttcatatgct tgtggtatag
    19741 atacaaatgg aggtcaatca cctctaaatg ggattgaatc aaatatagat aaattatcaa
    19801 aagacgataa aagagaatta tataggaaga tagcaaaagc acagcttgat gcatggagaa
    19861 atggaagtgg tcactactat tggaattata agttattact agatacagtt aatgaagaag
    19921 gttggatagg atgggatagt tgggacctag gcaaatgtgt agctcaagaa tggtatccta
    19981 tagaatatta aactaaaatt ggaggaaaag atatgattaa aaaccctata cttccaggtt
    20041 ttaatccaga tccttgtatt tgtagaaagg gagatgatta ttatcttgta gtttcatctt
    20101 ttgaatggtt tccaggtata cctgtttatc actctaaaga cttaaaaaat tgggagttat
    20161 atactcatat tttgacagat gaaacaaaaa tagatttgaa gaagcttcct tcatctaaag
    20221 gaatttgggc accttgtttg acttattgtg aagaagaaga tttattttac atagtttatg
    20281 gaattatgaa ctctatgaat gcaagatatt ttgatgttga taattattta attacatcaa
    20341 aagatataaa gggagagtgg agtgaaccag tatatataca ctcatcaggt tttgatgcgt
    20401 ctattcttca tgatgatgat ggtaaaaagt ggattgcatc attagactgg gagactagag
    20461 aaggatatga aaaacctggt gttatatgtt tagtggaata ctgtacaaaa aagaaagaaa
    20521 tagtaggata tccaaagaga atatggtcag ggggaactga tagaggttgt attgaagcac
    20581 cacatataac aaagcgtgga gattactatt atataatgtg tgcagaaggt ggaactggat
    20641 atggtcatag tgtaactatg ggaagggcta aaaatatatg gagaccttat gaaaaagatt
    20701 caatgaatcc aattgtaact tcaattccag gcgattttta tgaaagacat gaccctgacc
    20761 atctaaagcc taaatactat aatccagaat caaaacttca aaaatctggt catggaagct
    20821 atatagaaac aacatcaggt gaagtatatt tagttcatct aacatctaga ccatttgtac
    20881 cagagttaag gtgtacttta ggtagagaaa cagctattca aaaaatgaaa tggacaaagg
    20941 ataattggct tcgaatggaa gatgaaagta atttggcaaa agaatacgta tcagaaagta
    21001 aactagaaga acatttagtt tcatctatac caagttttga tgactttgat tcaaatgtat
    21061 taggtttaca gtactatgct cctaggattt caccattatc atttgcagat gttaagtcta
    21121 gaccaggata tgtaaggatt agaggtcaag aatcaagaac atcattaaat aaagtaagca
    21181 tattggcaag aaaattaact tcagtatatg caagaataac cactaagatg gagttttacc
    21241 cagaggtaca tcagcatagt gcgggtttga taatgtatta tgataatatg aattatataa
    21301 atttaagaaa gtattatagt gaaacattgg gtcaaagtgc actatcaata atacatcttg
    21361 aaaatggaga gaagacggaa tttttaaata ctaggatacc aataaaagat ataccaatat
    21421 atcttcgtct gtatatacaa ggtcgtaagt catattttga atggagttat gatgaaaaaa
    21481 actaccaaag aataggaaag gtatttgata caactaagtt ttcagatgag tactgtaaat
    21541 atggagaatt tacaggtacg tttataggat taacttgtgc agatcgtgta aagcataaac
    21601 actatgctga ttttgatttt tttgaatata tagcagatga atcaaaagat gtcgattaat
    21661 aaaatcatta ctaaaatttt cagagcaaag gtaaatctta tgctctgaaa taagaaacat
    21721 tagaaggcaa atcttacaaa aaggagtatg gtattatgaa tacagaagtt aatgttaaag
    21781 caactacgat tagatatgaa aagatttcat tttttgaaag aatttcttat ggttgtgggg
    21841 atttggggtg caatatcata tactcagcta tgtcagcatt tttgctgttt tattatacta
    21901 attatgcaga tgttagtgca gcagctgtag gtagtattat gcttgtatct aggatactgg
    21961 atgggtttag tgacttaaca atgggaatta tagtggatag aactaaatcc aaatacggta
    22021 aggctaggcc ttggattttg agaatggcga ttccttttgc tatagcagca gtattattat
    22081 tttctgttcc atcaaatctt ggtatcactt ctaaattaat ttatattttt attacatata
    22141 acttagtttc tactgttatt tatacagcaa tcaatgtacc ctatgcaact ctaaattcac
    22201 ttataactca aaaccagtat gaaagaggag tattaagtat atttagaatg atattagcca
    22261 cttgtggtac cttactaata aatggactta cactacctct agttgaatac tttggaaata
    22321 atttatcagc atggactaaa acattctttg tatttggaat agcatctata atggtatttt
    22381 ttataacatt tactggaacc aaggaaagag taaaagcagt taagcaagat aggaatgaag
    22441 taataccatt taaaataggt attaaatctt tatttagaaa taagtactgg atacaaataa
    22501 cattatgttt agtttgcata tttattgtat ttgcgataaa tggtggttca tccgtatatt
    22561 atgcaaagtt tattttggga gatgaaaaat tatttggtcc tataaatatg gtttcaaata
    22621 tatcccaaat tatagctatg tttatggttg ctccttttat aaaaaaattt ggaaaaagaa
    22681 atgtattaat agtaggttca ataatattaa tatcgtcaaa tgttatgttt ataatagttg
    22741 gacaaaacta tataggagta atatttgcaa gtgctataaa gggaatagga agtgctggaa
    22801 tagcatcaac aatgtttgct attgtttcag atactattga atatggagaa tggaagactg
    22861 gatatagaac tgaggggctt ataaatagtg catctagttt tgggtttaaa gtgggaaatg
    22921 gattaggttc agcaatatta ggtgcagtat tatcaattgg tggttatgta ggaacatcag
    22981 ctactcaaag tgatttagct atagtatcaa taaaagtatg ttttatatac ctacctatat
    23041 ttataacaat attacaaatt atcataatgt ttttttataa gcttgataaa gaatatagta
    23101 ctatacttaa tgaattaaat actaaataat gaaaaagttt cttataaagt cttaagttta
    23161 attaaggtct attgtaaatg ttccctataa aaactattat atatttatga ttattgaaga
    23221 atttttagag aagcgaataa taaaaatata agaagacttt aaatgatgaa atggttggtc
    23281 ttttagaaat gatttaataa gttattttta tttaaagcat tataagtgga caattaattt
    23341 ttaatttatg gagatgatat ttaacaatta gaagtaatat ataatatgcg ctaagaagca
    23401 atttttcaac tatttatgaa ggtggtggta caagaaaagt atcacctttt ttttgttata
    23461 caaaaaaaca gttgactttt tatatgaacc ccttctataa tgttactgaa attaagtaaa
    23521 atgattgaac aaatgtaaag ataattgaaa agcttgattt tggaggaaat caaatgaaaa
    23581 aaattggaga cttaagatta atgatgaagt gttgttcact ttattacgaa gataatttga
    23641 atcaacagga aatagcaaat caattgggaa tatcaagacc aacaatatca agaatattaa
    23701 aagaagcttt tgaacaagga atagtaaaaa tacagatagt tgatgttttg aaaaatgatt
    23761 accaaaaaat agagagaagt ttggagagaa aatataaatt aaaagaagta atagtagtag
    23821 atgataaaca agatgcacta acacaaaaac aagaactagc aagagctgta tctgaatatt
    23881 taactagagt agtaaaggaa aatgatataa taggtgtttc aataggaaca acactaaaag
    23941 aaataccaag atatgtggaa aaaagtaact gtaaaaatgt tacatttata cctctattag
    24001 gagggattgg agacaatgaa atagatattc atgcaaatca aatagcagta agtctagcga
    24061 gggcttttgg aggtgatttt aaattattac atgctccagc tgttatgtct gacttgtcta
    24121 caaaagagaa actttgcaaa gacgaaaaaa ttaaagaagt actagattta atagataaaa
    24181 caactatagc aattgtgggt ataggaaatc ctatgagttt aaactcaaca ataatggctt
    24241 ctggatacat gaatgaagca gatatagaag atttaaaaaa atacaactca ataggtgcaa
    24301 tttgtttaca agcctttgat aaagaaggaa aaacttctat acttgaattt aatcaaagag
    24361 tattaggagt gaaactggaa gatttaaaaa agataaaaag aacaataggt gtcgcttcag
    24421 gagatgaaaa aatagaggca ataaaggcat cattaaaagc gaaatttata aatagtttag
    24481 caattaatca cagtttagca cttaaattat tagaagattg tgactaatag aaagatagat
    24541 aaaagttaac aggagggaat gtatatgtca atatcaaaag aaacattgct tgaaatgtat
    24601 aagagaatga atcaggctag aaaatttgaa gagaaagtta gttggttttt tgcaagaggt
    24661 atggttcatg gaacaactca cttatctgta ggtcaagaag cgtcaagtgt ggcggctgta
    24721 atggctttag aaaaaggaga tttagtatca ttaactcata gaggacatag tcaatttata
    24781 ggaatgggaa tagacctaaa taaaatgatg gctgaactta tgggtaaaga aactggattt
    24841 tgtaagggaa aaggaggctc aatgcatata gcagatattg agtcaggtaa cttaggagca
    24901 aatggagttg taggtggagg tcttacaata gctccaggag ctgcacttac acaacagtat
    24961 aaaaaaacag gcaaaatagt tttatgtagt tttggtgatg gagcatcaaa tgaaggtact
    25021 tttcatgaag gaataaattt atcttcaata tggaaattgc caataatatt ttactgtgag
    25081 aataatttat acggtatgtc aacaagcata aaacgtcata tgaatataga aagtattgcc
    25141 actagagcag cttcttatgg aatagaagga atatcaatag atggatataa cccaatagaa
    25201 gtatacgaaa cagtacaaaa agctgctgag aagtgtagaa gaggagaagg acctgtatta
    25261 attgaaagta gaacttatag atggttaggt cattcaaaat cagatgcaaa tgtatataga
    25321 acaaaagaag aaatagaatc atggaaagca aaagacccta ttgaattttt aaaaaattat
    25381 cttatagaaa ataatctatc taatgaagat gaattagata agattcaaga atttgcaaag
    25441 caatcaatag aagatgcagt agagtttgct caaaatagcc caaatccaaa aatagagtct
    25501 ttattagagg atgtatatgc agactaagaa tggtaaagga ggaaaataaa aatgagtaca
    25561 agggaattaa catatgcaca agcaataaag gaagcaatgt cagaagaaat gagaagagat
    25621 gaaaatgtaa tatttatggg agaagatata ggaatatatg gaggggcatt tggtgtatca
    25681 gttggtatga tagatgaatt tggaccagaa agagtaaggg atactcctat atcagaagca
    25741 gctatagcag gagcggcagc aggtgcagca gcaactggtt taagacctat tatggaagta
    25801 atgtttatgg actttgtaac aatttctatg gatgcaattg taaatcaagc ggcaaaaatg
    25861 agatatatgt ttggaggaaa agcacaagtt ccaatggttg ttagatgtcc aggtggttct
    25921 ggaactggtt cagcagagca acattcacaa agtttagaag cttggttttg tcatgtacca
    25981 ggagtaaaag tagttgcacc ttctacacca gcagatgcta agggattgtt gaaagcagct
    26041 ataagagata ataatccagt catatttgtt gagaataaat tgttatacag aaaaaaaggt
    26101 tttgtgccag aagatgatta tgtaattgaa attggaaagg cagatattaa aagagagggt
    26161 actgatgtta cagtaattac ttatggaaga atgttacaaa gtgttgaaga agcagcagag
    26221 actctatcaa aagaaaatat aaatgttgaa attatagatt taagaacttt atatccatta
    26281 gataaagaga ctatagtaaa gagtgtatgt aaaactggga gagttttaat ttgccatgaa
    26341 gcagctaaga ctggtgggct aggtggagaa atatcagccc tgataacaga aagtgaatca
    26401 tttgattatt tagatgctcc agtaaaaaga atttgtggaa aagatgtgcc aataccatat
    26461 aatccagagt tagaaaaagc agttgtccca agagttgatg aaatagaaga agcaataaaa
    26521 tctttaattg ttagataagg agggatagat atggtggcaa ataaaataaa agccacacca
    26581 gcagctagaa gtcaggcaag aaaagacaat ataaaattag ataggctgat tggaagtgga
    26641 gaaaatggaa ggattcattt agtagatgtg ttaaattatt taaaagataa taaagcaaat
    26701 actactcctt tagctagaag aatagcagaa gatttaaata tagatttaga aactattgta
    26761 ggtactggat atagtggaaa gataagaaag tgtgatgtgg aaaaattaac tgcaaaagaa
    26821 actattgtat caaataatac atctaaatat agtgagaaaa aagagctgaa aattgaaaat
    26881 gaaaattcaa gcatgtttaa cacagtagaa ggaatatttg aaaagccaaa tccaatgaga
    26941 gctactgtag caaaacgaat gtcagaaagt tattttagtg ctcctgtatt tacattcaat
    27001 atagaagtag atgctacaga attgaaggta cttagagcaa agttaatcga cacagtaaaa
    27061 gaatcaactg gagtaaaatt aactatgaca gatttaatag taatggcagt atctaaaata
    27121 cttccaaatc atcaagcctt aaattcagca tggacagatg agggtatatt tagatataaa
    27181 gatgtaaata tagctattgc agttggttta gatgaaggct tatatgttcc ggtagtaaaa
    27241 aatgcaaaca aaaagtcttt aaaagaaata gcaaaagaaa gcaaagaact tgcggaaaaa
    27301 gtaaagacag ggaaacttat gccagcagac caagaaggta atacatttac aataagtaat
    27361 gttggaatgt atggtataac tacatttaca cctataataa atatgccttc aagtgcaatc
    27421 ttaggggtag gtgctacaca agataagttt gttccagtaa atggagaggc taaaataaaa
    27481 cctataatga acttatcatt aacatcagac catagagtaa tagatggaac agtagctgca
    27541 aaattcttaa aagatttaaa agaattgtta gaaaatcctt tatcaatgct tgtataggtt
    27601 ttgatatttc gttactgata taaatagttt gaatagatta tattattata attgtttcag
    27661 taaatttaaa gcttttatat attaagaatt atttttaaca gtaactatat gtgaatatga
    27721 tttgcttaat taaaatatat gaaaataaat aggaggagag cctatgtcag tagaagtaat
    27781 aatgccaaaa gcaggagtag ccatggaaga aggtactata gtatcttggc taaagcaaga
    27841 aggcgaagaa gtaaagattg gagaacctat actagaaata acaacagata aagttaatat
    27901 ggagatagag tcagaaggag aaggtacact tgctgtaatc atacataaag aggaaggtga
    27961 agtattacca gtatttacag taataggtgt aatagcagaa aaaggggaaa atcaagagga
    28021 agtaaaagct aaatatttat ctggaaatgt ttcaaaagaa gatatagttg aagagaatca
    28081 aaatatagaa gttaaagaag aaaaaataaa caaaaaagag tgtaatcatg attatgatgt
    28141 agtggtaata ggaggaggac ctgggggata tttatcagca ttaaaagcag ctcttttagg
    28201 tggaagagtt gctttagttg aagaaaatat actaggaggt acttgcttaa atagaggttg
    28261 tatccctaca aagacttata taaaaacagc agaaatatta gaagaaattg accaattatc
    28321 aaagagaggt gtaaaagtaa ctgtagataa agaacaggac attaagaagg ccataaaata
    28381 taaaaataga gtagttaaaa aacttacagc tggtgttggc ggattattaa aaagtagaga
    28441 tgtagatgtg tttaatctta aagctagtgt taaagaagag cataaagtaa ttttatcaga
    28501 tggaaaagtt ttagatacag aaaatataat aattgctaca ggttccaaag taaggatatt
    28561 acctataaaa ggaatagaat caaatttaat aataactagt acagaagcat tagatttgga
    28621 aacagtgcca gaagaattag taataattgg tggtggagtg attggttgtg aatttgcaga
    28681 gatattcaat tcaagaggtt ctaaagtaac tatagtagaa atggaagata gagtaatccc
    28741 aagaatggat aaagagttaa gcgaatcttt aaaatattct cttagtaaaa aaggtataaa
    28801 tgtattaact aaaaagaaag tttctgaatt taaagaagaa ggaaataaca tattagtgtg
    28861 cattgaaggt gaagtgccaa taaaagcaga tttatgtcta tatgctatag gaagagaagc
    28921 taatctttct ggcatagagg acttagatat taaaatagat aaaggttcaa tagttgtaaa
    28981 tagtaaaatg gaaacaagta taccaagcat atatgcagta ggtgatgtta ctggaggtgt
    29041 aatgttagct catgctgctt ttaaaatggg agaggtagca gcttcaaatg ctctaggtgt
    29101 gaataaagaa gttgacttag gtgcattacc tagttgtgtt tatacaattc cagaagtagc
    29161 atcagttggt attacagaag aggatgctag aaaaaaatat aatgtaaaag ttggtaagtt
    29221 taattttgct ggaaatggaa gagctttagc ttctggtcaa gaacaaggat atgtgaaagt
    29281 agtagcagat gctaaatatg gagaaatttt aggtatacat atgtttggat gtggtgtagc
    29341 agaacttata aatcatgcag catcatttaa agcattagag atacctactg atgaagcaag
    29401 tgagttgata tttggtcatc catgtacttc agaagcttta atggaagctt tggcagatgt
    29461 aaatggagaa tgtttacact tacctaaaaa ataaatctaa acataaatta ttaatttaag
    29521 tctattatta atattaattt atatcataaa attttaaaac acttacttag ccatacccct
    29581 tattatgcaa ataatttatt tgtataataa ggggtatttt ttatggaaaa atatagaata
    29641 tagaatcctt gtagtttttg ttgtacaaaa aagatagtaa tataaaataa cattatcatt
    29701 ttagaatgat ttcaattgta attaggaaaa gtgatttttt tgtttttaaa aaaagtatta
    29761 tttgtaaaat ataaaaaaaa atttcttaat atttgaataa aagaatagct taatttaaat
    29821 gttattactt tataaaaaaa taataagtac aaaaaaaaca atatatggca tataagttgc
    29881 tatataaata ataaggaggg aacaattata aatgaggcaa agaataaaaa acttaattga
    29941 aaatgaagat aagaaaaatc ctttaacaga tgaagcgatt tcaagtaggt taaatattcg
    30001 aagagaagat gttacctttt tgagaaatga gttaaaaata gaagattcaa gacaaagaag
    30061 aaaagttgtt ttaattaaag ctataaaaga tattttaaaa gaagaaaaaa ctataaataa
    30121 aaatgatata acaagaagat taaacagcat tgggtttaca gtatcaagat ttacagtcat
    30181 acaatactta aaagagattc aagattctgg tgacctaaaa cttgataaag agagtgatga
    30241 taaaaaagaa gaaataatca ataatagaga aaataaagat atagcatttg ataaactcat
    30301 aggtagtagt ggtagcttaa gtacaattat aaaactagcc aaagcagcaa ttctttatcc
    30361 acctcatggt cttcatacta ttattatggg gccaactggt gttggaaaga gtgagttagc
    30421 agagtgtatg tataaatttg cagtagaatc atccagattc cctaagaatg caccatttat
    30481 agtttttaat gcagcagatt attcagagaa tccacagctt ttgctatcac agttatttgg
    30541 acacgttaaa ggtgctttta caggagctga tgagaacaaa gaaggattag tatcaaaggc
    30601 agatggagga atattgttta tagatgaaat acatagatta cctcatgaag gtcaagaaat
    30661 actatttcaa ctgattgata aaggtatggt cagaaagtta ggagaaacaa gactaacaca
    30721 taaaatagat gtaatgatta tttcagcaac ttctgagcca atagattctc atttacttaa
    30781 tacatttaaa agacgtatac ctgtaacaat tgaaatacca gaattagttg caagaccatt
    30841 aaatgagagg tttgacatta taaataattt cttcttaata gaagctcaaa gaatgggagc
    30901 aaacatacat ataaagtcag atgtattaaa agctcttatg ctttacgatt gtataggtaa
    30961 tgtaggtcaa cttagaagtg atattcaagt agcttgtgct aggggactat taaaccaact
    31021 tacaaacaaa ctaaaagaag taaatataag catatcagat gtacctggat atgtaaaaca
    31081 aggtcttata aaaatcagaa attgtagagg taaaatagaa aattatgtag atggggattt
    31141 aattatagat tcaaatcttc aaggtgagat agaaaagaaa aatgaagata tatatacttt
    31201 tccagatgaa atatacaaac ttactgaaag aagacatatt gatttattgg aacaaggttt
    31261 agattttgat gttataaata gaatcattgg aggagaatta gaaagttgca ttcaaaaata
    31321 cataaaacaa gttaaaaaag tttctattag taacaatctt ccagatataa gtccaattgt
    31381 tggaaaatat atcgtagagc taacttatga agtaatcaaa atagcatcac aatacctaag
    31441 ttcactagaa ccgaatctac atttatgttt agcagttcac ctaaaagcag cttttgagag
    31501 attaaaagaa ggaaaagtaa tatcaaatgc tcatttgaaa gaaataatag gaaattatcc
    31561 actagaatat tctgtagcag aaaaggtagc tcaatattta aaggaaagat ataatataaa
    31621 cttaccaaaa gaagaaatag gtataatagc aatatatttt aaaatgagta gtagaagaga
    31681 tatgtctgaa caaaaaaaga taggtgtact tcttatggct cacggaagag tagcatcttc
    31741 tgtatgtgag gttacaaata aactattagg aattaatcac gcaaggtatt tagatatgcc
    31801 atttgagaag aagccggaag aaatgattga agaagctact acaataataa aagatattga
    31861 tgaaggtaga ggtgtgatta tattagtaga tatgggttca ctttcatatt ttggagatat
    31921 tatttctgga aagactggaa ttaatataag gacaatatct agatttgata cattgctttc
    31981 tatagaggtt atacgaagag cagttttacc agatttaaca atagacgaga tagttgatga
    32041 agttaaaggt atagagccac aagtaaaaga aaaggttagt aaatgtaaca atacaaaagt
    32101 agattttaga aaacctataa ttttaacatt atgtattact ggattagggg gagcttgtaa
    32161 gataaaaaaa atcctagagg aaaatattaa aagtataact gaaaaggttg atatagaacc
    32221 tataggtatg attgaatatc caagtcttga tttagagata aaacaaataa gcaatgataa
    32281 aaatgtaatc gccatagttg gaacaattga ccctcagata gcaaatatcc ctttttttag
    32341 tctagtagac ataaatgata aagcaaagtt aaatcaaata aataacctaa ttgatacaaa
    32401 tcaaattggt gaaacaaata aaaaatatga attatcagat ttaatacata aagaagatat
    32461 atttgtggat ttacaggtta aatcaaaaga agaagttcta aaatatatga gtaaaaaact
    32521 tagagagaaa ggttatgtga caaaaaattt ctataaaaaa gtagtggaaa gagataactt
    32581 atttccaact gaattatcag atgaaatagc aatacctcac acagatggaa tagatgtaat
    32641 taggccagct ataagtatag ccatcttaaa gaagcctatt gtgtggagta aaagtaaagt
    32701 aaaaataata cttttattag ctgtagacca aaagtgtttt aatccattaa gcactctact
    32761 ctcatttata gaaacagatg aatttaagaa gataaaaaac attaaagata gagattttat
    32821 tagggagatg atattagatg gagtcaatga aaataattag tagcaattta atttttaaaa
    32881 atattgaagt gtctaacaat gaagatgcat taaagttttt gggacaacgt ttgtttgacg
    32941 aacagtatgt aaaagaaagc tacatacaag ctgttgtagc aagagaaaaa aagtatgcta
    33001 caggattacc aacagaaata tacggagtgg caataccaca tacagatata gtacatgtaa
    33061 atgagccagg aatagcaatt ggaatactga ataaaccagt aaaatttata atgatgggta
    33121 cagacgatac tgaaattgat gtaaaagttg tatttatgtt agcagtgaaa gagccacaag
    33181 aacaattgca actattagaa aaacttatga ctatatttca agataagaat atactaaata
    33241 atattgttga cttaagtgaa gaaagtgtga gtgatttatt aaactctaaa ttgaaaaatt
    33301 aaacatgtaa agtatattaa aaatgtaaaa ttaaacatgc aaagtatgtt aaaaaatata
    33361 aaaagattat taaagatttc taactataga tatctttaaa ataaaataat ttcaatgggg
    33421 gtgactaatg tgactaaaaa gatattagtt gcatgtggaa caggagtatg tacttcaaca
    33481 attgctataa acaaattaaa gaaagcactt caagacattg gtaaattgga tatggttaat
    33541 attacacaat gtaaagtagt agaagttgca tcaaaagcac ctgattatga tttaataatt
    33601 tgtactacac aagtatctag tagtataaaa acaccagtga taaatggatt acctttttta
    33661 actggtgtcg gaatggataa attaatcaat gatgtattag aagagttaga attataatta
    33721 aaaaaattaa ggaacatggt ctctaaaatc ataagtttta gagacttaaa attaaataat
    33781 ggagggtctt tatatggaga tattaaattt cattgttggt ctaggtgcac aagtaatgat
    33841 gccaataata atatgtattt ttggtttgat attaggtaca aaactaggaa aatctttaag
    33901 agctggttta actgtgggag ttgggtttat aggtcttaac actattatag ctttgctaac
    33961 agataattta ggtccagcta cacaacaaat ggttaagaat ttagggctaa gtttatcaat
    34021 aatagatgta ggatggccag cagcatcagc tatagctttt gcatcaacag taggggcttt
    34081 aattattcca ataggtcttg tggtaaatat agttatgcta attactaata ctactcaaac
    34141 tgttgatgta gacatatggg attactggca ttttgctttt acaggagctt tagtggcagg
    34201 ggctactcaa agtgtaatgt ggggagtatt tgcagcagta gcaaatatgg taattgtatt
    34261 ggtaatggca gatttaactg ctccaggtat agaggaatat ttaggtatgc caggtatatc
    34321 tcttcctcat ggatttacac aggcatttgt tccaattgct atagtagtaa ataaattatt
    34381 agacctaata ccaggtataa ataagattga gataaatgct gatacattgc agaaaaaatt
    34441 tggattattt ggagaacctt taataatggg gtctgtaata ggtgtaataa ttggtattgc
    34501 tgcgaaatat gatataaaag gaatattaca attaggtgta actatgggag ctgtattaat
    34561 attaattcca aagatggcag cattattaat ggaaggatta ttaccagtat cagaagctgc
    34621 acaggaattt attgagaaga gatttaaaaa cagaggcaag atttatatag gcttagattc
    34681 agcagtagga ataggtcatc ctgttacatt atcagttgca ctagtgttgg ttcctttgac
    34741 tatacttata gcagctatat tgccaggaaa taaagtttta ccatttgcag atttagcagt
    34801 aattccattt gcacttgtat taatcgtacc aattacaaag ggaaatgtgt ttagaacatt
    34861 aataatagga ataattataa ttacttctgg attattaatc gcaactaact tagctccatt
    34921 atttacccaa atggctttaa atgctagctt taaaatgcct gaaggagcaa ctatgatttc
    34981 aagtatttgt gatggtgcga atccattaag ttgggtattt gtaaaagtta tgaactataa
    35041 agttattgga ggagtagttt ttggagttat agctttagga atggctattt acaataggaa
    35101 tagaataata aatgaaaata aaaagctatc tatagaagaa taaggttaaa acaattttat
    35161 taaggagtgt ataggttatg aaaaaatata aatatgattc taaaaggtac ttactcagtg
    35221 ttacaatacc aggatttttt atgattttaa tattgattta tgcactgttt aataactata
    35281 taaattttaa tttgaatata tatagtttgt taataattgt ctgtacttat ggtatattca
    35341 atacttttat atcatcaagt aatcctaaaa aaattattat tgacagcaaa tgtatacatt
    35401 ttacctcatt tatgactaca cataagtatg aaattaaaga tatagaaaag ataagaataa
    35461 gagaatttta taataaaaaa atttatctaa aaattaatga tggagacctt tttaaaggta
    35521 ggtattggat aagaacaaat atgtttaata atagtatagc attatatagt tatttcattg
    35581 agttggaaga gtgcttatat ccagattcac taagatttag aaataaaaaa tttgagaata
    35641 agaatatata aaaataaaaa attgaattga agcctaactt aatctttttt gataagatat
    35701 aagtttgaac tttatactaa atttttagaa ttttcaatca agacaataac ataatagcta
    35761 agcaattaga acacaactaa gatgtataag gcatgtatat gatgaatggg aggatttaat
    35821 taatgttatt agagaaatta agaaaagaag tattacaagc atctttagac cttttaaact
    35881 ataatttagt gacattaaca ggagggaatg taagtgggag agatgaacaa actggctata
    35941 tagcaatcac cccaagtgga atggattata gaaatcttac accaagtgat attgttatag
    36001 tagatgtaga tggaaatatt atagatggaa aatggaaagc atcagtggat ttatcagacc
    36061 acttgtatat atataagcat agagaagaca taaatagtat aattcataca cattctacat
    36121 actcaagttg ttttgctatt ttaaatgaac ctatagaatg cgcaagtaca actcttgcaa
    36181 atgaagtagg gggttcagta ccagttgcaa aattttcacc accaacattt aaaaagatgg
    36241 gaaaatgtgt tattgaagca attggtgaca aaagagcatg tcttttagca aatcatggcg
    36301 taattgcagt tggtccatct gtaggacatg ctcttacagc cgctgtaatg ttagaagatt
    36361 cagcaaaagt atattactta gcaaaatcaa ttggcacacc agtgctactg cctgatgaag
    36421 aaattcaaag agcgagagat gtatttttta atgtctatgg tcaggataaa taaattagat
    36481 aaaattttaa aagtaatatg aaaatataga tattcaatga tattaaggag atttataatg
    36541 atataataag tttaatagtt aagaagtaaa atatgaaatg taatagtata taaattcatt
    36601 taagactaaa aataataaga taaaataaaa aggagtctgt atttctatgt attacttatt
    36661 aaacaaaagc acaaatcctt actttaattt ggcattagaa gaatatctat ttttaaatga
    36721 taaatataat gatgatatta taatcatatg gagaaatgaa gactccattt ttataggtaa
    36781 aaatcaaaat ccatatcagg aagtacatca tgatgttatt gaaaagggag aaattcctat
    36841 tttaagaaga atatctggag ggggcactgt ttatcatgat ttaggtaata tcaatatgtc
    36901 attcatacaa aaagataggc aacttcatga gatagatttt ttggagcata ctaagtttat
    36961 gcaaaagatg ctttcaacct taggactaga tgtatctata actgaaagaa aagatttatt
    37021 tttaaatggg aaaaaaattt caggctctgc acagtctata aaaagaaaaa attctcttta
    37081 tcatggaact cttctttacg attcagattt aaataaatta actaaatatt taaattcaaa
    37141 taaagcaact gaatcaaatg caactaaatc tgtttcaagt aaagttacaa atattaagtt
    37201 tttactcgaa aaagatataa attacttttt agattattgt gttgaatatt taaaatctaa
    37261 tataaagaat ataaaagaac ttgaattgga tgaagaagat attaaaagtg tatacaatat
    37321 aggagaagat aaatatagaa agatagagtg gacatatggt aaaacgccga aatttcaagt
    37381 agtgctacca tttaataatg aaagtaaaat aaatatacat gttaacagat ggaaagtatc
    37441 aaaatttttt atttcttatg atgataatgt aattaatatg gataagttgt tagatttgaa
    37501 tttctttaaa gaagaaataa aagagagtat tttagaaaat tatccacatt acatagattt
    37561 aatcaattta atattttaat ataaaacctc taatttgata aaattgtctt atatcaaact
    37621 agaggttttt aatattcttg catattaaca accattacaa aattgtaaaa ttaaaaacaa
    37681 cactattgaa aaatcaatat atattgtaat aaatatatgt gtttttcatt agcaaataga
    37741 cattaactat ttatacaact gaaaatttaa tatataatta atcagatggt taaaataaaa
    37801 atattaaaag ttttaataaa tgatggttaa aaataaaata cgaggtgata ccatgtacag
    37861 tgttataatt gttgcagcgg gaagcggaag gagaatgaac ttagatataa acaaacagtt
    37921 cataaaatta agagaaaaag aaattattgc tcatacaatt caagtttttt atgaaaatat
    37981 aaatatagat gaaatagtgg tatgtataaa aaaagaagaa gaggattttt ttaaagaaaa
    38041 tataataaat aagtataact ttaaaaatat aaaaatagca tatggcggaa aagaaagaca
    38101 ggactcaata tataatggtt taaaaaaatt agatgaaaat tgtgatatag tacttatcca
    38161 tgatggagca agaccatttg tcgaccatag aataatcaac gaatctataa aggtagctaa
    38221 agaaaaaaag gctgtggttg taggtgttcc agtaagtgat actataaaga tagtgtcaga
    38281 tggaacagta caagaaactc cagaaagaaa tttgttgtgg gcagcacaaa cccctcaaac
    38341 ctttgaatat aatctcataa tagatgctta tgagcaagca tataagaaca attattatgg
    38401 tactgatgat tcaatgttgg tagaaaatat aggtcaaagt gtcactatgg taatgggttc
    38461 ttatgaaaac ataaaaataa ctagtccaga agatttaaat atagcagaac aaatattaaa
    38521 tatggaaaaa agagatgaag ttaacagtag aaggagaatt atatgagaat aggattagga
    38581 tatgatgtac acaaattaac agagaataga aaacttataa tcggtggtgt agagatacca
    38641 cacgataaag gtttgttggg tcattctgat gctgatgtat tgatacatgc aataatggat
    38701 tctattttag gtgctctagc attaggagat attgggaagc atttcccaga tacagatgaa
    38761 gaatataagg gagcagatag tatgaaatta ttagaacatg tgtataatct aataacaagt
    38821 aaaggatata aaattggtaa tatagatagt actataattg ctcaaagccc taagatggct
    38881 ccatatattg agagtatgag aagtaatata tcaaaagttt taaacacaga cattgataat
    38941 ataaacataa aggcaacaac agaagaaggt cttggtttta caggagcaaa acagggaata
    39001 gcttcacaaa gtatttgttt attattgttg acaagtcaga ataattaata tattattagt
    39061 aataagttta atggatatca agtaataggc ctatatagaa tatctataat gtatgaattt
    39121 aagtgaaatt aatataaata taaaattagc tatgataaag aaatagtaaa atgatgaaat
    39181 cttcacagag agaaaacggt ggtgagagtt ttcaagagga agtctttgaa cctgtctttt
    39241 agcttaaagg tataaaaatc tttacggtag gaaccgttat attcccaaaa gagagctatt
    39301 catatagcta actagagtgg taccgcggaa attaaacctt tcgtctctat acttgtatag
    39361 agatgagagg ttttttatat tttcaggaag ttaatattca ggaggaatct attaatgaaa
    39421 atgtcaaaaa tgtttatgcc gacattaaaa gaaatcccag cagatgctga gattacaagc
    39481 catcaattaa tggttaggtc aggcatgata aaaaaaatga cttcaggtgt ttataaccaa
    39541 ttaccaatgg ggttaagagt gttcaaaaaa attgaacaaa taattagaga agaattaaat
    39601 aaaaaagatt gtcaagaaat actttgtgca gccttacttc cttctgaatt atggaaagag
    39661 tctggaaggt ggactgctat gggtgaagaa atgtttagac taaaagacag aacagaaaga
    39721 gagtactgtc ttgggccaac acatgaagaa gcattcactg atataataag acaagaaatt
    39781 acttcatata aacaattgcc actgaacttg taccaaatac aagtaaaata tagagacgag
    39841 agaagaccaa gatttggtgt tatgagaact aagactttta caatgaagga tgcatatagt
    39901 tttgatgtag atgataaagg tttagataag tcatatcaag atatgtttga tgcatatgta
    39961 agtatatttg atagatgtgg attggagaat agccctgtac aggcagattc aggagctata
    40021 ggaggttcta catcagccga atttatggtt aagtcagaag ttggtgaaga tgaagttgta
    40081 ttttgtagtg gatgtgatta tgcagccaat gtagaaagag cagaatcttg taatctagca
    40141 tcacaaaaag aagaaatgaa agaattagaa gaggttcata caccaggagc agctacaata
    40201 aaagagttag aagaattttt aaaaacttct ccagataagt ttgctaaaac tttagtatat
    40261 gaggcagatg gaaaaacagt tgtagtcgtt gtaagaggag atagagaagt taatgaaatc
    40321 aaagtatcta atgctatagg ttctgttata gaatttgctc ttgctacaga tgatgtagtg
    40381 agaaaagtaa ctaatgcaga agtaggattt gcaggtccaa taggtataaa tgctgactat
    40441 gtatttatag ataaagaaat tgttgaacaa agaaacatag ttgttggggc taataaaact
    40501 gagtaccata taaaaaatgc taactatgga agagattttg aaggaatagt tggagatttt
    40561 agaaatgttc aagaaggcga ccagtgtata gtatgtggta agccacttga aatagctaga
    40621 ggtgttgaag taggacatat atttaaacta ggaactaagt actcagaatc tatgaatgca
    40681 aacttcatag acaaagatgg aaaatcaaag cctatagtaa tgggatgtta tggaataggt
    40741 gttgaaagaa cagcagcagc tataattgaa caacataatg atgagaaagg tataatatgg
    40801 cctttgtcag tagctccata ccatgttgtg atagttccag caaatatgaa aaatgaagaa
    40861 caaatatcaa tagctgaaaa tatatataat gatttgcaag ctatgggtgt agaagtttta
    40921 ttagatgaca gagatgaaag aataggtgtc aaattcaatg attcagaatt aataggaata
    40981 cctatgagga ttacagtagg taaaaatatt aatgaaggta aagtagaatt taaacttaga
    41041 cataaagaag ataaagagat aattgacata gaagaaataa atgaaaaagt aaaggcagag
    41101 tttatcagga ataatgttag gttaggataa taacttaaat aagatattgt atagataatc
    41161 aaagttgtac tttatagaca ccattttatc tatatataag gatataaaat ggtgtttttt
    41221 tataaaacaa ataaatgagg aggtaattga aatggcaaaa aatgaaaaac aatttgttga
    41281 agaaataaca aagatggaag atgattttcc acaatggtac acagatgtaa taactaagac
    41341 tgacttagtt gattatgcac cagtaaaagg ttttatggtt gtaaagccat atggatatgc
    41401 attatgggaa aagatgcaag aatttatgga taaaaaattt aaagaaactg gacataaaaa
    41461 ctgttatttt ccattattaa taccagagag tttattaaac aaagaagcag aacacgttga
    41521 aggttttgct ccagaagttg catgggtaac acatggagga aataaaaaat tagaagaaag
    41581 attatgtgta agacctactt cagagactat aatatgtaca atgtatgcga aatggttaaa
    41641 atcatataga gaattaccat atctttataa tcaatggtgc tcagttgtta gatgggaaaa
    41701 atcaactaga cctttcttaa gaacatctga gtttttatgg caagaaggtc atacattaca
    41761 tgaaacagca gaagaagcac aagaagaaac aatacaacaa ttagaagtat ataaagcgtt
    41821 atgtgaagaa ttacttgcaa tgccagttgt agctggtcaa aaaagtgaaa gtgagaaatt
    41881 tgcaggtggt gaaagaacat atactataga agctatgatg catgatggta aagcattaca
    41941 atcagggaca agtcacttcc taggtcaaca ctttactaag gcttttgata ttacttttgc
    42001 agatagagaa ggaaatttag ctaatccata ccatacatct tggggagcat ctacaagact
    42061 tataggtgga cttataatga ctcatagtga taacagaggt ttagtattac caccaagagt
    42121 agctccaatt caagttgtta tagttcctat agctgctaaa aaaggaaatg taatggagac
    42181 tgttgataaa atatatgctg atttaaaaac taagggagta gccgtagaag ttgatgatag
    42241 agataactat acaactggat ggaaatttaa tgagtgggaa atgaaaggtg ctccagtaag
    42301 agttgaaatt ggaccaaaag atatagaaaa taatcaagct atggtattta gaagagatac
    42361 tttagaaaag gattctatgc ctttagaagg attagctgat gctatatgtg atttatttga
    42421 tgttatacac aatgatatgt ttgaaaaagc aagaaaacat agagaagaca atacatctat
    42481 agttgaaaat atggatgagt ttagaaaagc tttagaagaa aagccaggat tcataaagac
    42541 tatgtggtgt ggagatgcag aatgtgaagc taagattaag gaagaaacag gagcaactat
    42601 aagatgctta ccttttgaac aagaaaactt aggtcacaag tgtgtgtact gtggaaaaga
    42661 agcagatagt atggtagtaa tggcaaaagc ttactaaaat acatttaaat aaaaactggg
    42721 gtagaaagta tttaatactt tatcccagtt tttttgtttt ttatgagtaa taaaatgtat
    42781 ttgtaactat gtcataagat aagtcataga tacttatatt aaaaagaata taatagagaa
    42841 ctatttttaa taattacata ttaatgaaag caaaatattt ttgttatata gattttcaat
    42901 aaagcaaaca ataaatataa atgaatatta gtaaggagtg cttttaattt ttagaaaata
    42961 aatgacttaa aagaaagatt tatgaaatta aaactaggat tttctgatat aataaacatg
    43021 tgtattttta aataaaaagg atattattat tagatttgat taaaaataaa cttgcaaaac
    43081 aatgtactag tttaatatta tagttatatt gaataaaata tcaggaggaa gtaaaaatga
    43141 atgtaagagt aaggtttgca ccaagtccaa caggatttgt acatataggt agtttgagaa
    43201 ctgctttata taactattta tttgcaaaaa aaatgggtgg agaatatata ttaagagtgg
    43261 aagatacaga ccaaagtaga ttagtagaag gtgctataga gaatatgctt aatgctatga
    43321 aatgggctgg tgtcaaccat agtgaaggtg ttatattaga tgatagtgga aaagtagtac
    43381 aaaaaggaga atatggtcca tatattcaat ctcaaagatt agatatatac caagaatata
    43441 taaagcaact tttagatagt ggaaaagctt attattgttt ctgtacaaaa gaaagactgg
    43501 atgaagtaag agatgctcaa agagcagcag gagaaacagc taaatatgat ggtcattgta
    43561 agaatctttc taaagaagaa gtagaagcga atataaaagc aggaatacca tatgttataa
    43621 gattaagatt gccagagaat catacaatta agtttacaga cttagttaga ggagatatgg
    43681 aatttaatac taatgaccta gatgaccaag tattaatgaa aacagatgga tttccaactt
    43741 atcattttgc agtagttgtt gatgactatt tgatgaaaat tacacatgtt ataagaggag
    43801 aagaatgggt atcatctact ccaaaacatg tttatttata tgaagctttt ggatgggaag
    43861 cacctgtatt tgtgcattta ccaaatatac ttaataaaga aaagaaaaaa ttaagtaaaa
    43921 gacaaggtga tgtagctgtt gaagacttta agaaaaaagg atatttacca gagggattag
    43981 taaactatgt agcattagtt ggttggtctc ctgaagataa tcaagaattg tttacaatgg
    44041 aggaattaga aaaagccttc tctgtagaaa gagtatctaa aagtggtgga gtatttgata
    44101 ctgaaaaatt aaattgggtt aatcagcact atataaaaga tggtgatgat gcttatctaa
    44161 cagacttagc aataccattt ttagtagaag atggatttat aacagaagaa gaagctacta
    44221 ataaatatga tttcttaaag agtatgatat cagtacttaa agagaaatta caatatgtaa
    44281 aagaaattac tgaacatgca agtatatttt ttggagataa aatagaggta gaaactgaag
    44341 agggaagaga gttcttaaga ttagaacata tacctacttt aatagatgct ttgagagaaa
    44401 aaatagaaaa aacagaggta ttaaatgctg agtttgttca agctatgctt aaagaaatac
    44461 aaaaagagta caaaataaaa gggaaaaatt tatttatggg ctcaagaata attttgacag
    44521 ggcaaatgca tggtccagat ttaccaaaag taatggaagt tttaggaaaa gaaacttgct
    44581 taaatagaat agcttatgta aaaaataata tattatagtc ataaaagtcc gctaatttag
    44641 aagcggactt tttttgtgtt agtatttggt gaaaatatct gcttaagaaa atgaaggtat
    44701 ttaaggtaat aaatttaata tataaaaagc aaagcaaaaa tataaataaa atatgaataa
    44761 taaactaata aaatattaag catagaagaa gggaatctat tattttagtt tgatttaatt
    44821 attaaggggg taattactat gtatagtaat attgatgatg ttaaaaagga attaaaggag
    44881 ctatgcttag aatatgttac aattttagaa aaattaaaag atgaaaaaat gattacagaa
    44941 gaaacttttg aaaagtgctc ttctcaaaaa aaaatatttt tagaagaaca atagaggatg
    45001 gtaatagtat tattattatg tagtttgaaa gatagtacga aaaatgatag taatactatt
    45061 atttattgca attttcaact ataatataat atataatgtt aagaagataa tttataaaaa
    45121 tacagtgagg tgatgagtgt gaaagtttat aatacattga ctagaacaaa agaagaattt
    45181 gttccattag aagaaggaaa ggtaaaaatg tatgtgtgtg gtccaacagt ttataactat
    45241 atacacatag gtaatgcaag accatttata atatttgata ctctaagaag gtatttagag
    45301 tatagaggat acgatgtaac ttatgtacaa aactttacag atgttgatga taagattata
    45361 aatagaagtc atgaggaggg aatatctcct gaagaagttg cggctaagta tataaaagaa
    45421 tattttgtag actgtgatgg gctagggata aaaagagcta ctgttcatcc tcaggttaca
    45481 gataatatac aacagattat agagtttata aaagagttgg aagataaggg atatgcatat
    45541 gcagtaaatg gtgatgtata ttttgataca aataaatttg aaggttatgg aaaactttca
    45601 ggtcaaaaac aagaagattt agaggcaggg gctagaattg aggttaatga ccaaaaaaga
    45661 catcctatgg actttgttct ttggaaggca aaaaaagaag gtgagccagg atgggatagc
    45721 ccttggggag aaggtagacc aggatggcat atagaatgtt ctgttatgtc taagagatat
    45781 ttaggtgaaa caattgatat acatgcaggt gggcaagatt taacattccc acatcatgaa
    45841 aatgaaatag ctcaaagtga agctagaagt ggaaaaatat tctcaaaata ctggatgcat
    45901 aatggatata taaatataaa tgatgaaaag atgagtaaat caaaaggtaa tttctttaca
    45961 gtaagagata tatcaaaatt atatgattta gagatagtaa gatttttcat gttatcagca
    46021 cattatagaa atccagtaaa ctttagtgat gagatgttaa atcaagctaa agcaggtctt
    46081 gaaagactat ataatactaa agaaaaatta gaatttacgc taagtaattt agtagaatct
    46141 cctttaacag aaaaagaagt agagcttgtt aaagaattag atgactttag acaaaaattc
    46201 atagatgcta tggatgatga tgttaataca gcagacgcag taagtgtaat atttgaatta
    46261 gctaagttaa taaattctaa tgtagatgaa aattcttctt tggagtttgc taaaaaatgc
    46321 ttagatgaat ttaatgaact tacaggagta ttaaatattg taaataagaa aaaggatact
    46381 gtattagata aagacattga agaattgata caaaaaagaa ctgatgcaaa gaaaaataaa
    46441 gagtttcaat tagctgatga tattagacaa caattactag atatgggaat tgtattagaa
    46501 gacacaagac aaggtgttaa gtggaaaagg atataaaaat ggaaaaaact gaattagtta
    46561 ctatgtcacc attagtttta gcatacttag gtgatacagt gtatgagaca tatataagag
    46621 aatatttaat tagacagaat acacaaagaa aagttaatga tttgcataaa ctagctataa
    46681 agtatgtaaa agctaaagct caggcaacta taattcatga aattgaaatt gagttaactg
    46741 aagaagagag taaaatttat aaaaggggaa gaaatcaaaa gtcaaatact tctcctaaga
    46801 atgcagatat tatagactac aaacatgcaa ctgggtttga ggcattagtg ggatatttgt
    46861 atttaaataa tgaaatagag agacttcaat atattatcaa taaaggaatc aaaattattg
    46921 aaagagatat gtaaatatta aagagtgttg tcttaataat aagtaataag gcaacacttt
    46981 ttttataact aatgtataat aaatatatag aaattagtaa tgagaaagga taagaaagtt
    47041 atgaaagtaa aattaatatc acatacacct gaaccagaaa aagtaatagc tatggcagct
    47101 aagctatgtt attcaccagt tgggacagac gaaatagaaa aagatttcta aaatatatta
    47161 aagagcattc ctataacaaa tactatggcg gttggaatct atgagaagtt atagatatag
    47221 aattatgtaa attatttgga aaaaacaggt ttgaaaatta gccatgttgg tatttctagg
    47281 ttacttaagg aagatcaaac ataaataagc tgagttgtct taggtgcact atgtacaaca
    47341 ttagaatgtg aagttgaaga tttattactt caaacgaacg atggtactaa gaaaaacaat
    47401 gatgaaatga ttaattaata ataaaggtaa ggaggtagta tatgagttta gcagataaaa
    47461 tttttattga tatgtgtaat aatattcttg aaaatggagt atcatcagat ggagaggtag
    47521 ttagagcaaa atgggatgat ggccagcctg ctcatacaat aaagaagttt tgtgtagtaa
    47581 ataggtatga tctttcaaaa gaattcccaa tacttacact aagaccaaca aacttaaaag
    47641 cagcaataga tgaattactt tggatatggc aaaaaaaatc taataatata aatgatttga
    47701 atagccgtat ttgggatagc tgggctgatg aaacaggttc aatagggaaa gcttatggat
    47761 accaaattgg acagaaacat aaatacaaag aaggagaatt tgaccaaata gatagagtga
    47821 tttatgactt gaaatataat ccttatagta ggagaattat aactaatata tataatcata
    47881 atgatttaaa tgaaatgaat ttatatcctt gtgcatatag tatgacattt aatgtaactg
    47941 gaaatagatt gaatgcaata ttaaatcaaa gatcaaatga tattttggta gctaataatt
    48001 ggaatgtaac tcagtatgca attttagttc acatgttagc acaaataagt gatttggaag
    48061 taggcgaatt ggttcatgtt atagcggatg cacatatata tgatagacat attcctctag
    48121 ttaaagagct tattaataga gaatcttatg atgcaccaaa attaataata aatccaaaca
    48181 taaagaattt ctatgacttt agagttgagg actttacatt agaaaattat aaaagtgggc
    48241 cacaaatcaa aaagattcct gtggcaattt agaaggagtt atttatgaaa gttatagtag
    48301 ctgtagattt aaattgggga attggttatg gtggaaagtt actacagtcg attcctgaag
    48361 atatgaaatt ttttaaagaa aaaactgtag gtaatgtagt tgtaatgggg agagaaacct
    48421 ttaaatcatt accaggaaaa aaagcattaa aagatagagt gaatatagtc ttgactagaa
    48481 gtaaatcttt taatgatgat agattgattg tttgtaattc tatagatgaa actcttaagg
    48541 aactacaaaa atatgaaaat gataaaattt ttataatagg tggagaaaca gtatataaac
    48601 aatttttacc ttattgtaat gaactatatg taacaaaaat acagaagaca tatgaggcgg
    48661 atagattttt ccctaatata gatattatgt caaactggga tttgattaaa gaaagtgaag
    48721 taaaagaata taacaatata agatatgttt tttcaacata tataaataat agtttatagg
    48781 tttgtatagg agagaaattt aatttatgaa aaaggatata tttgtaaata gagtttctaa
    48841 tgctttagaa aatgatagag gcgcagtttt tgtaggtagt ggtatatcgt ttagttcgac
    48901 tgaagttgat tggtttaaat tactggagcc attagtaaat gaacttgata taacattaga
    48961 caataaaagt gatgatttac ctatgattgc tcagtacata gtaaataatt attcaggaaa
    49021 tagagggcct ttagtaaacg aaatatcaaa aacatttaat agaaagttta aactaaacaa
    49081 gtatcataag tatttagcaa caactaaact ttcaacaata tggacaacta attatgatat
    49141 gttgttagaa gatgcatttt atgattttga tacatcggtt aaagtaagtg atgattctat
    49201 tacaaggaat agactagaat atgatgtgga aattataaaa atgcatggat gtatttctag
    49261 atccgattgg aatgaaatag ttataactca agaagattat gatgattttt caataaataa
    49321 accagctata tctcaaagat taagtgaaga tttaataaat aagtcttttc tatttattgg
    49381 atatagctat agagatccaa atataagaaa tataatgata aatgctagaa ggctaagtaa
    49441 aaaacatact caacaacatt atataatttt aaaaaagtta aaagatagtg atagtaatat
    49501 tacgcaagat gatgtagtaa gacaagaact ttggtgcaat gatttaaaac gtttgggaat
    49561 ttcaacttta tttatagatg aatactcaga gttagaggaa cttttaagag agataagtca
    49621 aaaatcaaga ggtaaaacag tatatgtgac aggttctcat aaagaaagca atatgaatgc
    49681 aagaaaatta ggaaccaagc tagcaaaaca taaagatatt actttactaa gtggtcaatc
    49741 atctggtatt ggctcagagg tagttgctgc gtttactgaa gagtgtatta agagtaaaga
    49801 agatattata aatagaatga aaatatttcc taatccatat tcagctgatg aaaaatactc
    49861 tgatgatatt actttaatac cagatttaaa gaaatgtaga actaaaatgt tgaattcaac
    49921 acaagttgta gttgtattta gtggaggtat aggtactgaa gcagagatag atgttgctat
    49981 aaaacaaaac tgtaatataa ttcctgttat aacatgtaaa gaggatagag agaatccagc
    50041 tataaaaaaa atcttaaact atagtgataa tatgaaaaat atagaaataa aagatgctac
    50101 ctattataat aaaatagtag atgaagatgg tgttgtaaca atggaggaaa tttatatatg
    50161 catatcaaaa ataatgaatt aaaacatgac attattaaat tgaaaaaaag aaatggattt
    50221 attgaagttg gaaaagataa aaaaacgttg gtaaactgtt taattggagc gaatgaatta
    50281 gaggattaca aatatgaaat aaaaaaaata gattgtatac ttaatatatc agaaaaacca
    50341 gatatagttt cagatttaag tactaaaaga agaaaaataa gtgaatctat atggtataag
    50401 atagttaaag atacaccttt cgtatctgct acactgccca tatacttagt tagtaaaaat
    50461 aataataaaa tagatagtaa tgaattatta gatataatta ttgagcagat ggaaaatgga
    50521 gttgggatga taacgattca tccaacagca aataaacaaa tttttgagga ttctaagaat
    50581 agaatggtac ctgtcacatc tagaggtgga ggtatggtaa tacaagattt aatctcaaaa
    50641 aatttttcag aagataatgt gtatttgaaa atattgccag aaattataaa gtatgctcaa
    50701 aaacataatg tttgtatcag tctaggtgca acatttagat caggaaacat atttgattct
    50761 aatgatagag cacagataac agaaattaag agtcaaatag aattagctaa gaggatatat
    50821 aaaagtaatg tcggggttat tattgaatca ccaggtcatt caagaccaag tgacataatt
    50881 aaaatatcgt caatattaaa aaaagaaggt ttcccaatta tgccactagg accaatacca
    50941 acagatattg caataggaat ggatcatatc gctgcagcta ttggtgctac aattatgggt
    51001 atagaaggat gtgcaaatat aatatcaact gtcacacgag aagaacatac tggagggaga
    51061 ccttctattg aatccacagt tgaatctata agaacagcaa aaatagctgc tcatattatt
    51121 gatatacatc aaatgaatga tattaactta gatatgagtg tatctaagtc tagagctaaa
    51181 tctaacacct gtatatttgg gaaagataca agatattgtg acagatgtag agaactgtgt
    51241 cctttgtgca ttagataaaa attatattca agttaattca ataaaaaaga ttggataaaa
    51301 atacatcgta tagctagttt ttcacaacag agtcaaagat atgtcaaatt agagcaattt
    51361 gaatacataa ttcctccaga aatagaaaaa atagaaaaag caaaagagtt atttataaat
    51421 tcaatgaaaa aataccaaga ggattatgat aaattagtag agatactatt tgaaaatcat
    51481 tataacaaac taataaaagg tggtaaaaac gagaaaacat caaaaagaca agttgagaag
    51541 aaagcaatag aagatgctag atacgtattt ccaaatgcgt gtgaaacaaa gatggtattt
    51601 actataaatg ctagaagttt gtttaatttc tttgaacata gatgttatga aaatgggagt
    51661 tgtctagaag gaactatgac ttgtggagat atagttcaag ttagaaaaaa atttaagaac
    51721 ttgtaggagg tgaataattt ggcgagtata gaaggaagaa atccggtaat agaagcaata
    51781 aaaagtgaca gagaaataga taaaatatta attgcaaatt cagctaaaga aggttcaatt
    51841 aagaaaataa taggaatggc taaagataag aatataatta ttcagtatgt tgataaacat
    51901 aagctagatg aagtaagtac aagtcattca catcaaggtg taatagctta tgcaagtgag
    51961 tataagtatt atgaattaga tgagctaata gatttagcaa agaataaaga tgaagaccca
    52021 tttttcatta tattagatga gataacagac ccacataatt tgggttcaat aataaggaca
    52081 gcagatgcag taggagcaca tggagttatc attccaaaaa gaaggtctgt acacataact
    52141 cctgtagttg ccaaagcatc tgctggagca gtagaatata tgccagtttg caaggtaacc
    52201 aatatagtta atacaataaa aagactcaaa gaagaagggc tgtggattgc tgcagctgat
    52261 atggatggag aaacttttta taaacaaaat cttactggtc ctcttggtgt agtaattgga
    52321 agtgaaggtt ttggaatatc tagattggtt aaacaaaact gtgactttat agtaaaaatg
    52381 ccaatgatag gtaatgttac atctttaaat gcatctgtag caggtggaat acttttatat
    52441 gagatattca gacaaagact ggataaaagt aaataggcat gaaaaaaaat ataaatcatt
    52501 acttaataat agatggctac aatattataa atgcgtggga caatttgaaa gaactggcta
    52561 aagaggactt agaagattct cgagaaaagc ttattgatga cattatagaa ttttctgagt
    52621 ttatgggtta taagactata atagtttttg atgcttataa tgttaaaaat tctcgagaaa
    52681 aagttgaaaa aagaaaacac ataacaatag tttatacaag agaacaccaa acagcagata
    52741 gttatataga gaaatttata acttctttat caaagtatga tgatgtaaaa gtagccacta
    52801 atgactatgc agaacagcaa atgattttag gaaaaggtgc tactagaatg tctgcaagag
    52861 aattaaagtt agagttagat cgttccaaga ataaaatgaa ggaaaaaaat atcggtttga
    52921 ggaaaaaaat tcagcgaaat tggttggagg aaaggttaga taaagaaaca ttgtcgaaac
    52981 ttgagaacat tcgtagaaag cgttgaaatt actaggttct ttagactata atatacctat
    53041 aaatttgttt tatatatggg ggagatttac atgttggtag caaaagaaaa aagttatgag
    53101 ttagtggaca attgtcagca ggatgagtat aacattgtat taagagcaag tgaaggggat
    53161 aaaatagcac tagagtacat tattactaaa tacagaaatt ttgtaaaggc aaaagcaaag
    53221 tcatattttt taattggagc agataaagaa gatataatac aagaaggaat gataggcctt
    53281 tataaggcag ttagagattt tgatggaagt aagaccaatt catttaaatg ttttgcggag
    53341 atatgtataa caagacaaat aataactgct ataaaaactg caacaagaca aaaacatata
    53401 cctttaaatt catatgtttc tttgaataaa ccaatatatg atgaagagtc agacagaaca
    53461 cttttagata ttatagctac aagtatagta acagatccag aagagcttat aattagtaaa
    53521 gaagagttaa aaaatataga atcaaaaatg aacgaattgt taagtgactt ggaattagaa
    53581 gtactagaat tatatttaaa tggaaagtca taccagttta tagcggacaa gcttaaaaga
    53641 gatgtaaagt caatagataa cgctttacaa agggttaaga gaaaattaga aaaacatctt
    53701 gaaaacagaa atgattaata gtaaaatact taccataagc ttattgtgag caaaattaat
    53761 ttatatcgaa agataaggga ggaaattcaa aatggctaaa gctaaatacg aaagaacaaa
    53821 acctcatgtt aatataggga caataggaca cgtagaccac ggtaaaacta cattaacagc
    53881 agcaataaca aaaacattat atgacagata tcaattagga gaagcagtag atttcgcaaa
    53941 catagataaa gctccagaag aaagagaaag aggaatcaca atatcaacag cacacgttga
    54001 gtatgaaaca ccaaatagac actatgcaca cgttgactgc ccaggacatg ctgactacgt
    54061 taagaacatg ataacaggag cagcacaaat ggacggagca atattagttt gttcagcaac
    54121 agatggacca atgccacaaa caagagagca tatactatta tcaagacaag ttggagtacc
    54181 ata
//
LOCUS       DAEQJM010000022        53238 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.022, whole genome shotgun sequence.
ACCESSION   DAEQJM010000022 DAEQJM010000000
VERSION     DAEQJM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53238
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.022"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(222..1334)
                     /locus_tag="KRQ43_001645"
     CDS             complement(222..1334)
                     /locus_tag="KRQ43_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH2742004.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     AEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            1623..2187
                     /locus_tag="KRQ43_001646"
                     /pseudo
     CDS             1623..2187
                     /locus_tag="KRQ43_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
     gene            2432..4159
                     /locus_tag="KRQ43_001647"
     CDS             2432..4159
                     /locus_tag="KRQ43_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742005.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSARVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            4159..5949
                     /locus_tag="KRQ43_001648"
     CDS             4159..5949
                     /locus_tag="KRQ43_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742006.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(6111..6419)
                     /locus_tag="KRQ43_001649"
     CDS             complement(6111..6419)
                     /locus_tag="KRQ43_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742007.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(6681..7229)
                     /locus_tag="KRQ43_001650"
     CDS             complement(6681..7229)
                     /locus_tag="KRQ43_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742008.1"
                     /translation="MIFLNENVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTIEILRKVLFERSEERAIAMRERALENGDELIADNIISTTDVPFLGWVPEFKE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            complement(7337..8002)
                     /locus_tag="KRQ43_001651"
     CDS             complement(7337..8002)
                     /locus_tag="KRQ43_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2742009.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDVYKTTLIHMETPKYINLEDFC
                     NNK"
     gene            8398..9303
                     /gene="garR"
                     /locus_tag="KRQ43_001652"
     CDS             8398..9303
                     /gene="garR"
                     /locus_tag="KRQ43_001652"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBH2742010.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            9439..10821
                     /locus_tag="KRQ43_001653"
     CDS             9439..10821
                     /locus_tag="KRQ43_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH2742011.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAVLIGGWIYGKRFEKYPAYAIDENDREKN
                     LEKGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKRYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            10892..12328
                     /locus_tag="KRQ43_001654"
     CDS             10892..12328
                     /locus_tag="KRQ43_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBH2742012.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNELLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPVETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTHGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKVLGGVSDKEMLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(12514..13368)
                     /locus_tag="KRQ43_001655"
     CDS             complement(12514..13368)
                     /locus_tag="KRQ43_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742013.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(13636..13959)
                     /locus_tag="KRQ43_001656"
     CDS             complement(13636..13959)
                     /locus_tag="KRQ43_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH2742014.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            14162..14791
                     /locus_tag="KRQ43_001657"
     CDS             14162..14791
                     /locus_tag="KRQ43_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742015.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKNNGVQTSK
                     VVSASANMDEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMNATIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            15103..15612
                     /gene="ruvC"
                     /locus_tag="KRQ43_001658"
     CDS             15103..15612
                     /gene="ruvC"
                     /locus_tag="KRQ43_001658"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBH2742016.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            15605..16207
                     /gene="ruvA"
                     /locus_tag="KRQ43_001659"
     CDS             15605..16207
                     /gene="ruvA"
                     /locus_tag="KRQ43_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBH2742017.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASSAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            16314..17333
                     /gene="ruvB"
                     /locus_tag="KRQ43_001660"
     CDS             16314..17333
                     /gene="ruvB"
                     /locus_tag="KRQ43_001660"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBH2742018.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            17651..18676
                     /gene="queA"
                     /locus_tag="KRQ43_001661"
     CDS             17651..18676
                     /gene="queA"
                     /locus_tag="KRQ43_001661"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBH2742019.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFLYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGNNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            18688..19173
                     /locus_tag="KRQ43_001662"
     CDS             18688..19173
                     /locus_tag="KRQ43_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742020.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            19252..20373
                     /gene="tgt"
                     /locus_tag="KRQ43_001663"
     CDS             19252..20373
                     /gene="tgt"
                     /locus_tag="KRQ43_001663"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBH2742021.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITSIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPQDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            20507..20800
                     /gene="yajC"
                     /locus_tag="KRQ43_001664"
     CDS             20507..20800
                     /gene="yajC"
                     /locus_tag="KRQ43_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBH2742022.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            20858..21220
                     /locus_tag="KRQ43_001665"
     CDS             20858..21220
                     /locus_tag="KRQ43_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HBH2742023.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            21286..21429
                     /gene="scfA"
                     /locus_tag="KRQ43_001666"
     CDS             21286..21429
                     /gene="scfA"
                     /locus_tag="KRQ43_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HBH2742024.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            22055..23950
                     /locus_tag="KRQ43_001667"
     CDS             22055..23950
                     /locus_tag="KRQ43_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HBH2742025.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKSETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            24412..25815
                     /locus_tag="KRQ43_001668"
     CDS             24412..25815
                     /locus_tag="KRQ43_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HBH2742026.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILIDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALVASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     DNGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKISDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     regulatory      25987..26072
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            26196..32159
                     /locus_tag="KRQ43_001669"
     CDS             26196..32159
                     /locus_tag="KRQ43_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HBH2742027.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGN
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNIGTDNIEYTIK
                     KLSASRSEIKNKDENVSYYNIVFNNLPVGKYNIEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDEDGNVQQ
                     IPYENKEYMKNLKDKEQQEEVNNEQEEVNQEEVNNKDENKNQTDNNSNNKDENNDKQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEGDNISKDDNSTTSTYSRAALE
                     TYTDVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSLKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESIDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVVYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEIRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIDRELKLAQDLYNDRATLTDVTTVNQ
                     EINKSGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLKTGKNVIQLSKLHSLDIECGGSLYIRYPEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNIGNSY
                     EYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKAKFTDSISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDVSTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPEAETRKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDDKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADQTRTNGIGKLAEDYVYQSDDPSTSEDETGKIPAGS
                     IIITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNAIDVSNKKVITVSNKVKGNIVRDK"
     gene            32369..34249
                     /locus_tag="KRQ43_001670"
     CDS             32369..34249
                     /locus_tag="KRQ43_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HBH2742028.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSVTCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRVE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTSDKPALK
                     IVTYNNKTVDYENINSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKITKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGSSSNSTSNVTVKKLKGADRFETA
                     TKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAVQFIKSNKVSNIYFIGGI
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVVDKIKSLI
                     EK"
     gene            34616..36217
                     /locus_tag="KRQ43_001671"
     CDS             34616..36217
                     /locus_tag="KRQ43_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HBH2742029.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADRQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEINEKVIQQCINASKSNGQPPTITVGSTEIYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSYDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKNLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            36436..38025
                     /locus_tag="KRQ43_001672"
     CDS             36436..38025
                     /locus_tag="KRQ43_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp12"
                     /protein_id="HBH2742030.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGTVKAPILLSQRNSIPSDTEKMLKDVKKV
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGNDRIETSYLIAKEIASIKPIDKVFITNGY
                     TGEADAMSASSVASRDGSPIILTNGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNIVAK
                     DSNGNDLTPELIGNIDTDKVGKYKVTIKATDIGGKTTSISVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYSLVNSYRKEKGKEPLQVSKNLEGLSNSWSKYMADKGQFSHVINGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDAREVANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILPNGEVYATQEFLNK"
     gene            38251..40527
                     /gene="slpA"
                     /locus_tag="KRQ43_001673"
     CDS             38251..40527
                     /gene="slpA"
                     /locus_tag="KRQ43_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HBH2742031.1"
                     /translation="MNKKNIAIAMSGLTVLASAAPVFAAEDMSKVETGDQGYTVVQSK
                     YKKAVEQLQKGLLDGSITEIKIFFEGTLASTIKVGAELSAEDASKLLFTQVDNKLDNL
                     GDGDYVDFLISSPAEGDKVTTSKLVALKNLTGGTSAIKVATSSIIGEVENAGTPGAKN
                     TAPSSAAVMSMSDVFDTAFTDSTETAVKLTIKDAMKTKKFGLVDGTTYSTGLQFADGK
                     TEKIVKLGDSDTINLAKELIITPASANDQAATIEFAKPTTQSGSPVITKLRILNAKEE
                     TIDIDASSSKTAQDLAKKYVFNKTDLNTLYRVLNGDEADTNRLVEEVSGKYQVVLYPE
                     GKRVTTKSAAKASIADENSPVKLTLKSDKKKDLKDYVDDLRTYNNGYSNAIEVAGEDR
                     IETAIALSQKYYNSDDENAIFRDSVDNVVLVGGNAIVDGLVASPLASEKKAPLLLTSK
                     DKLDSSVKAEIKRVMNIKSTTGINTSKKVYLAGGVNSISKEVENELKDMGLKVTRLAG
                     DDRYETSLKIADEVGLDNDKAFVVGGTGLADAMSIAPVASQLRNANGKMDLADGDATP
                     IVVVDGKAKTINDDVKDFLDDSQVDIIGGENSVSKDVENAIDDATGKSPDRYSGDDRQ
                     ATNAKVIKESSYYQDNLNNDKKVVNFFVAKDGSTKEDQLVDALAAAPVAANFGVTLNS
                     DGKPVDKDGKVLTGSDNDKNKLVSPAPIVLATDSLSSDQSVSISKVLDKDNGENLVQV
                     GKGIATSVINKLKDLLSM"
     gene            40763..43108
                     /gene="secA"
                     /locus_tag="KRQ43_001674"
     CDS             40763..43108
                     /gene="secA"
                     /locus_tag="KRQ43_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH2742032.1"
                     /translation="MSVLDAILDKADEQEIKKLNLIVDKIESLEKDMEIKENEQLKEM
                     TNTFRLRLDKGESLDDILPEAFAVVREVSKRVLGMRQYKVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVITVNDYLAERDKELMRPVYEFLGLTVGVILSNQD
                     PSIRKEQYKCDITYGTNSEFGFDYLRDNMVPDLSHKVQRELNFAIVDEIDSILIDEAR
                     TPLIIAGDGDEDLKLYELANNFVKTVKEEDFEMDRKDKTIALTASGISKAESFFGITN
                     LTDIKNIELYHHINQALRGHKLMEKDVDYVISNGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKNESKTMATVTYQNFFRLYEKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNRPVIRADLHDKVFKTEEEKYSAVVEEIIRIHKTRQPILVGTVSVEKSEKLSKMLKK
                     QGIKHQVLNAKQHDKEAEVISKAGKLDAITIATNMAGRGTDISLGAGDKEEEEKVKNL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TSSKENTAIESKALTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIKEDIQKMVKDIIQEAGETYLIGRKRDYYGYFKHLYSTFMPADTLLIPGVDKKS
                     VQEIIDSTYEISKRVYDLKKMMIGIDKVAELEKTVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEALNKNIREATVQYLYKFN"
     gene            43523..45394
                     /locus_tag="KRQ43_001675"
     CDS             43523..45394
                     /locus_tag="KRQ43_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HBH2742033.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRDLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTDTVTSKTIEIGIGDEKIDLTANPVDSTGTNLDPSTEGFRVNKIVK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISS
                     KDSETGKYKFTIKYTDASGKAIELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADVDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKADITDSQRNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            45501..46208
                     /locus_tag="KRQ43_001676"
     CDS             45501..46208
                     /locus_tag="KRQ43_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH2742034.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYKEGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDELAINKIQYVHAP"
     gene            46241..48076
                     /locus_tag="KRQ43_001677"
     CDS             46241..48076
                     /locus_tag="KRQ43_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH2742035.1"
                     /translation="MKISKKIVSLLTMTFLTVTLYGNTSNASTKDTLTGSGRWETAIK
                     ISQAGWKKSENAVLVNDNSIADALSATPFAKAKDAPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALSSEIEKQLNAENISFERISGNSRYDTSLKLAEKLDREKSISKIVVV
                     NGEKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKDIEKSYVIGGTYSISN
                     SVERSLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTRSKHDLIDSLAVGV
                     LASKNGSPILLAGNKLDSSQKDVLNTKIIDKVIQIGGLGNENVVEDVIDMQEETKYTV
                     ETIDELNVAIKKSDANDIIRFKPEKDKNITNSFKIETNKAITIEFDGIYKQSITIDMP
                     NGDIKNFGDIDNDLVINNIKNETLVNEGSIQGIDVYDENGCKIENEDSGEIWLITILK
                     NSKDVYILNRGEITKISNNSSSVTIKNSGNINTISGSEEPSISGKKPITNDTDKDEDK
                     KARGLYPKVESCIPALKDYVRITISTKPESSKYKIYYRVVDEKPSAKYVGEKISTKGW
                     SMVTISNQSFIERAKDGSYIEAVEIDTSNNEVSRWGKSSITDDGI"
     gene            complement(48124..48519)
                     /locus_tag="KRQ43_001678"
     CDS             complement(48124..48519)
                     /locus_tag="KRQ43_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBH2742036.1"
                     /translation="MILKKHRETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIEIRFVFKEFLSFVSFRLLSGVVEMLIMYVMIDLLF
                     VNDVIVKIFTNIVVIVLNYLFSKMIIFKK"
     gene            48746..51157
                     /locus_tag="KRQ43_001679"
     CDS             48746..51157
                     /locus_tag="KRQ43_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HBH2742037.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMDLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISIGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNESAFNELN
                     TLLGK"
     gene            51454..53031
                     /locus_tag="KRQ43_001680"
     CDS             51454..53031
                     /locus_tag="KRQ43_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HBH2742038.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVENLEAKVDSIEKAIDSISQKVN
                     KIQDILDKIGFLKKFLS"
BASE COUNT        21431 a         6064 c         9504 g        16239 t
ORIGIN      
        1 ggaatgagtc cgattgaata tcgaactcat tccgcataaa gatagccttt tttaagtctg
       61 tctacttgac agggacatat ccaattttga gacagcctct ttttttaaat ttatatttct
      121 agaatttatg ttttttattt atccaacatt aacattagtt attaacaata attttaagaa
      181 aaatatactt tcatgatgtt aatatcaaaa taaatatatt tttaaaggat gatttgtttt
      241 gaattttcac gaatatctac ttctatgact ttttctattg tatctcctct aaaacctaat
      301 aaattactcg tcaagtttgc agtggaacaa gaatgattag gtataattct tattctatca
      361 ccaattttta tatcagtttc accatttact ttaatttttc caacttcttc tgaaagtgaa
      421 tcaatagtaa gttctggatg tccacatacc ctaccataac caacaatact actatttcca
      481 tgtgcacctt tatcaagtcc aaggcactta cttccacaat caattaaata atatccactg
      541 ctattttttg agattacagt acacacaaca gtaagagcac acatatcttc agtagcacaa
      601 cctaaaccta tctgtatagc atcatagtat acatagtttc caggtcttac agcagttata
      661 gttttagaag cagcttcagc ttcaactgtt ggagtactac cagaagcgac aatttctata
      721 ttaaatccat tatcagttag agctttgtat gctttctcca tagaagaatc ttcttgaaca
      781 caaacatctg gaacaccttc tggagaacta caaccgtaca cttgacctgg atgcgaactt
      841 ataccaacaa tcttgatgtt ttctagctta gaaatttcag tagcaagttc aaccactttt
      901 tctggttcaa ccccaaaacg gtgtaagcca caatctacaa taataagtag cttgcactct
      961 atttttgatt tagaaaaagc ttcactataa gccttagcac attctatatt atctgtagca
     1021 cagattaaat ttatttttga tgccatagtc acaattctat ttatatttac ttctcccatg
     1081 taaggataag ccaacataat atcttcaaaa cctgctttta tcagagcttc accttcatca
     1141 agtgttccaa ctagaaaacc actagcacct gcattttttt gaagtctcgc tatgtaagta
     1201 cttttatgtg tcttaagcat aggccaaagt tgtttattat tatttgtaca aatttgttga
     1261 attttatcta tattcttttc taactggtct aaatctagca aaaaatttgg agtagcgact
     1321 tctgaaattt tcatgttatt taccaccttt caacaaaagt aaattaacta taattattat
     1381 attagtaata tcggctttat aatattaata gcttataatt atattataaa actagcgtta
     1441 acagagagca atatttattt gtaataatta gaattttcaa taagttagtg tgattttaaa
     1501 ttatttatat aatatatttt tagttttatg caaagtttat ttaaattagt ttgaggattt
     1561 attaataggg tattattgaa tgagtaaaaa agtgatgttt acatagaata atcacactat
     1621 aaatgttgga ggtagtaaac atgagaaaag tagtacttta tattgccaca agtttagatg
     1681 gttatatagc tgaagagaat ggcagtgtaa gttttttaga cgagatatct tcagaattta
     1741 agaatgagca ggaagatgat tataatactt tttacgatac aattgatact atcattatgg
     1801 gaaattccac atatgtacag attgcaaatg aattaagccc aaatgaatgg tactataagg
     1861 gtaaggaatg ctatatatac tcaaatacaa ttaatgggac aactggagaa tgtaaagtat
     1921 actaatttag aacctaaaaa attaattgag caaattggaa aaaagaagga taaaaaagat
     1981 atttggatag ttggtggagg cgatatagta aaattattta tgaaagataa cttaattgat
     2041 gattattata tatatatatt gccaataata ttggggagag ggatttcact atttaagtct
     2101 ggtatagata agactaattt gaattttaag aaagttagta atattggaga acttgtaaaa
     2161 ttggaataca gtaaaaaaca aaaataaatt acatgccaat ttgttacaat gttatgagat
     2221 gaagcattta aaagactttt agctatatga attgacatta cttgtcaaat atgttaacat
     2281 ataagcgact tgtcggaggg tgtattaaaa agaatatgct ggagaagaga gtgcgttaac
     2341 tcttttctcc tttttttata aaattaagca tttataaatt tagtattatt acatgattac
     2401 actatctcaa aaattaagaa aggagaaaaa tatgaaatta attttaagtt atttaaagaa
     2461 ttataagtta ttaatagtat taaacatact ggctatattt agttttgcat tagtcgagtt
     2521 ggggattcca actataatag ctaaaataat tgacaatggt attgcaaatc agaatatagc
     2581 ttacataaaa caaatgggaa tagtgattgt tattatttct attatagggg ttgtaggtag
     2641 tatattgttg ggttattgtt ctgctaaggt atcaacaagt gtaaccagag atataagaaa
     2701 tgacatattt gagaaatcac aagaattttc acatactgaa tacaataaat ttggaatttc
     2761 ttcaatgatt acaagaacaa cgaatgatgc atttcaaatt caacaatttg ttaatatact
     2821 actaaggact gccttattaa ctccagttat gttcatcata agtataataa tgacaattag
     2881 aacaagtgtg gaactttcta tagtattggc tatatcagta ccttttataa ttattggagt
     2941 agcaataata gcaaaagtat ctcaggcaat atcttcaaaa caacaaaaag gactagataa
     3001 attaaacctt atatcgagag aaaatttaac tggaataaga gtaattagag cttttggaaa
     3061 tgatgattat gaaacagagc gatttgaaaa aacaaataca tattatgcta atgtttctaa
     3121 gaaactattt aagcttatgt caattactca accagcattc tttttactat taaatatagc
     3181 tgttttggct gtattttgga tttcaagtga gaagataaat attggagagc ttcaagttgg
     3241 acagttggtt gcatttttgg aatatctttt ccatgccatg ttttcaatta tgcttttttc
     3301 aatggtattt attatgtatc caagagcaga ggtatctgca aatagaataa aagaactttt
     3361 aaatgaagaa ccattgataa aaaatcctga aaatggaatt aaggatactg aaaataaggg
     3421 tatcatagaa tttgataatg taacttttac ctatccagat ggagaagctt ctgtacttaa
     3481 ggatatttca tttactgcaa aaacaggtga aacagtcgct tttataggaa gtactggtag
     3541 tgggaaaagt actctaatta acttgatacc tagattttac gatgtaacag agggtagcat
     3601 taagataaat ggagtagata taagagaata tgatttaaaa gctttaagaa aaaagatagg
     3661 attcatacct caaaaatcac tgctttttac tggtagcata gcaaataata ttagatttgg
     3721 gaaacataag gcaggagagt cagaattaga atattccgca agagttgcac aagcatatga
     3781 gtttatatca aaaaaaccta gaaagtttga tgaattgatt agtgaaggtg gagcaaatgt
     3841 atcaggaggt caaaaacaaa gactttctat tgcaagggct attataagaa gacctgaaat
     3901 atacattttt gatgatagtt tttctgcact tgactttaaa acggatgcaa tacttcgtgc
     3961 taaattgaag aaggaaacaa aagatgcaat tgtattgatt gttgcccaga gaattagttc
     4021 tattattgat gctgataaga ttatagtact caatgaagga caagttgtcg gaatgggaac
     4081 tcataaagaa ttattaaaaa actgtgaaat atactatgaa attgcaacat ctcagttaaa
     4141 aaaggaggaa ttagaataat gaaaaagtct aaaggtttta agaaaacaat tggtagactt
     4201 cttccatttg taaagaaata taaattttcc tttattatag ctattatatg tataatttca
     4261 gcagctacta tgaatgcact tgcacctaaa actgaaggat tgataataac acaattgact
     4321 aaagatgtaa ttagtatcgc aaaaggagta ccaggggctt ccgtaaattt tgattatgta
     4381 acaaaaatat tggtgatttt agcatgtata tattttgcta atgcaatttt tacgtatact
     4441 tcaagttttc tacttacgaa tgctattcaa aacacaatga gagatttaag aaatgaagtc
     4501 gaaaataaaa taagaagatt gcctattagt tattttgata gtaatagttt tggagatgta
     4561 ttaagtcgta tatcaaatga tgtagataca atatcaaatg cattgcaaca gagttttatg
     4621 caaattgtaa actcaatctt agtcataatt ttggcacttt caatgatgtt tacaattaat
     4681 atatatatgg ctcttatagc tctttttata attccaatta gttattttgt atctaaattt
     4741 gtagtaaaaa aatctcaaag tagattttca ttgcaacaaa atgctcttgg aaaattaaat
     4801 ggaaaagtac aagaaatgta tactggattt aatgaaataa aactatatgg taaagaagaa
     4861 gattctataa aagaatttaa aaaagtaaat caagaacttt gtgaaaatgg atttaaggca
     4921 caatttatat caagtatgat gaatcctatg gtttcattag taacttactt tggaattgca
     4981 gctgtggcag ttgtcggttc tatatatgca gtaagtggag ggataacagt aggaaattta
     5041 caagcatttg tgcgttatat atggcagata aatcagccac tttcacaaat gactcagtta
     5101 tctacagtaa tacaatcttc ttttgcagct atagaacgtg tatttgaaat tttagacgaa
     5161 gaagaggaaa tacctgatgt tgaaaatcca gttaagatag aaaatgtaaa aggaaatgtt
     5221 acatttgagc atgttaattt tggatatgga gaaaattcaa ctttaataga agatttaaat
     5281 gcagaagtaa aaagtggtca gatggtagct attgttggac ctactggagc aggtaaaaca
     5341 acattaataa acttattgat gaggttttat gatgtaaaga aaggtgctat taaaattgat
     5401 ggagtagata taagagatat gaaacgtaaa gatttgcgtt caatgtttgg tatggtgctt
     5461 caagatacat ggttatttaa tggaaccatt tttgaaaata tagaatatgg tagatttgga
     5521 gctactaaag aagaaattat acaagcagca aaagtagcaa atgttcatca ctttataacc
     5581 actcttccag atggatacaa tatgttctta aatgaagaag catctaatat atctctaggg
     5641 gaaaaacagc ttttaaccat agctagagct tttatatcag acccttcaat attgatactt
     5701 gatgaagcta ctagttctgt tgatactagg ctggaactta tgcttcaaaa agcaatgaga
     5761 aatcttatga atggtagaac tagttttgtt atagcacata gactttctac aattcgcaat
     5821 gctgacttga ttttagttat gaataatgga agtattatag agcaggggaa tcatgatgaa
     5881 ttaatggaaa agggtggatt ttatgagaag ctttataata gccaatttgc agacaaagaa
     5941 tcagaataga taacataaac ttttgtataa aattttgtat caaattcaaa tattaatcat
     6001 ataattaaaa agagtatcag taagttgttt ttttatagat ttactgatac tctttgattt
     6061 taagactaaa ggtatttatg attggtactt ataattcaca actagtcttg ttacatctga
     6121 taaccagaat tacagtactt ttctttttta cctttttgtt ctctaacata taacaattcg
     6181 cttaacttat caatgtaata accatcatca cttatgcgaa ttaaactagt cagataatat
     6241 ccatctttgc ttctaggaat ctttttattt attgctaaat caatagctgt ctttgctgct
     6301 tcaaaatgct ttaaatgtgt atgaccttct tcaaaactct ttctagtatt ataaactaca
     6361 taaccttttt taacttgaaa aactataaat tctttctttt catatatttt attaaacatt
     6421 caatcagccc ttctcaagat agttttatag cataacatta gaagcttcta aaaaatttta
     6481 caaagaacat aaatatttta taaattataa atctaaaact ataatttata aagataactt
     6541 tctgattatt tatatgataa ttcatataga ttaaaagtaa attatcttta ggttaaacaa
     6601 aagtaaaata aaagactagt tataatattt atatgaaaaa gtacaaaata tagtatatga
     6661 atatagaaaa tttaaattat ttatttacag tttttatttc cataagtata tttaccttca
     6721 gataccttgt catcatggaa atatattctt tcacaacttt tatctcccca tagaatgttt
     6781 tttgttattt tatgggacgt atctcctgta aatacttcag ctacagtagt atctgtaaca
     6841 tcacagtaaa gagaagcgaa ttttttaaac caagggtttt cctcaaatct taaaagccag
     6901 gaagctccat aagggcaatg taactcttta aattcaggaa cccatcctag aaatggaaca
     6961 tcagttgtgc taataatatt gtctgcaatt aattcatctc cattttcaag agctctttct
     7021 ctcatagcaa tagctctttc ttcagacctt tcaaataaaa cttttcttag tatttcgata
     7081 gttttatctt caccaaactc ttcaaataac actttggaaa aataaaaata taagtcacca
     7141 aaatgtttgc atgccatacg aacttcttca atagcataat ctttgtcaat agtttcatta
     7201 gttacaacat tttcgttcaa aaaaatcact ccttagaata gtattagtta caatataatt
     7261 atagaatatt ttttataaat taggaaatta atttgaggta gatatatttt taataaatga
     7321 aagtataata ctaaaatcac ttattgttac aaaaatcttc taaattaatg tatttaggag
     7381 tttccatatg aatgagagta gttttgtaaa catcttcaat acatccattt gcaatattat
     7441 taaaaatatc tgtgtgttct tttaatgttg tttcaagcct tccttcatgt gataatgaat
     7501 cgagagctaa tttttttatt ctgtacatat agttgttaaa cattttgtca aattcagtat
     7561 tttgagcata tgaaactata gttgtgtgaa ataatgtatc gtattctgca aatgagttta
     7621 aatttttatc acctagtaaa atatcttttt gtttatctaa aagatgtttt aatttactta
     7681 tagtttctac tgccctagct tctttgtatt gacttgtaat taaaaaagta caaaaccctt
     7741 ctattgcaga gcgtatttgg aatatctcta caatttcatt tgctgtaatt tgatggattc
     7801 taaatccttt gcttgggatt atatctataa atccatcttg actaagtctt tgaagagcat
     7861 ctcttatagg tgttctagag atacctattt cactagcaag ttttgtttca gaatatattt
     7921 cattttctat catttctcca gatagtatca attcttttaa gtagtcatat gcttgttctt
     7981 gtaatctttt aaatgtagcc atacttaata atacccccct aaacaatata aaaatacaaa
     8041 aacttatata attttaagca tacaacatag tgaaaataag gtcaatcttt tgcaatttaa
     8101 attgcagata agattaaaaa atataaaaaa ttattgaagt gtgaagtatg attaacatta
     8161 aaggcagatt aattaaaact aattgaaatt agtaaaaata caaaactgta aaagtagcat
     8221 attatattta aaaacaatag tatgtattaa aacttatata ggatgactaa atataataaa
     8281 tgactttaaa aattactatt tattgttaaa ataaatactt ttatatttta tattgaccgg
     8341 tatactggta tgtagtatac tctaaaacat aaaaaacgtt ttcaaaaatg tgaagatatg
     8401 gagggttata aaatgaaatt gggatttatt ggattaggaa taatgggaaa gccaatggca
     8461 aaaaatttat taaaagatgg atgtaatctt ttggtgtatg acattaataa atctgctgtg
     8521 gatgaactta tatcatgtgg agcaaaatac gcaagtgttt tagaaatggg tcaagaatgt
     8581 gatattgtat ttacaatcct tccaaatgga actattgttc aggatatatt atttgggatg
     8641 gatggattgg caaaaacttt aaaagaagga agtatagtag tcgatatgag ttcagttact
     8701 cctacagaat caatattgtg tgcaaataaa ttaaaagata tgggcttaga atttatagac
     8761 tcaccagtaa gtggagggga gccaaaagcg attgatggta cacttgcttt tatggctggt
     8821 ggtaaggaag aaatttataa gaaagtagag ccatttttta atataatggg aagctcatct
     8881 attttaattg gagataatgg tagtggaagt gttacaaaac ttacaaacca agtaatagtt
     8941 aatttgacga tagcagcagt ttctgaggca tttgtacttg cagcaaaagc aggtgcagac
     9001 ccagaaaaag tatataaggc aataagagga ggcctagctg gtagtacaat attggatgcg
     9061 aagataccaa tgattatgaa tcgtgatttt aaaccaggtg gaaaaatatc tattaatttg
     9121 aaagatatta agaatgtaat gcaaacagca cacaatttag atgtaccgct acctatgaca
     9181 agtcaattat tagaaattat gcagacatta aaagtacatg gacatttgga agatgaccat
     9241 agtggaatag cacagtattt tgaaaagttg gcaggtgttg aaataaaaaa acacaataat
     9301 taatatttaa atatatcaat ataattaaat acatattatt aggattagat tatataaata
     9361 cagcgaggtt aagttatcat agtaaaagaa aaataaaatt gataaataat aaagtagaat
     9421 gataaagggg taaagattat gattacagga tatggacttt tgatagcatt tgttatatct
     9481 ataggaattt tacttgtatc gattattaaa tttaaagtaa atccgttttt ggcattactg
     9541 ataacatcta taattacagg ctttatggtt agaatgccta taaatgaaat atcaaccaca
     9601 atatcgactg gatttggaaa tacattaggt agtataggta ttgtaattgg acttggaata
     9661 atatttggaa atattctttc agaatcaaga gcaacagaat ctattgcaaa ggggttgtta
     9721 gctaagactg gagaaaaaaa cagtgcttta gcagtaacta cagcaggttt tttaatttca
     9781 attccagttt ttatggatgc agcttttgtt ataatgatgc ctataattaa gtatgtttcg
     9841 agagtaacta agaaatctct aatggttttt gtatgtgcct taggagttgg gactatagta
     9901 ggtcatgcac ttgtaatacc tacaccagga cctttagcag ttgcagcaaa tgtaaatgca
     9961 aatgtaggta gttttatact ttattctata attgttgctt ttccagcagt tcttataggt
    10021 ggatggattt atggaaaacg ttttgaaaaa tatccagctt atgctattga tgagaatgat
    10081 agagaaaaaa atttagaaaa gggaaaagat agcataaaaa ttgaagatga tgattcttct
    10141 aaagtaccag gttttggaat ttctatgttt tctttattgt tcccaatact tcttatactt
    10201 atatcaaatg tatttagtat gttcttagaa aaaggttcta caatgagtgg agtacttgca
    10261 tttataggag ataaaaacat agcaatactt cttggaatat tggtggcaat aggattttta
    10321 aagagataca taaataaacc tatgggagat gtagttattg aagctgctga ttcagcaggg
    10381 ctaatattat tgataacagg ttcaggtggt gcgtttggca gtgttataaa tgcaagtggt
    10441 ataggtaact tcttagttga tactatgtct ggtcttagta tatcagttgt agtgcttgga
    10501 ttcttattaa gtgctttgct tagaatttct caaggttctg ctactgtagc cttagtaaca
    10561 acatcatcaa ttttaggacc tacaattttg gcaactggaa tgtcaccagt tttagtaggg
    10621 cttgctatat gtgctggagg agttggtttc tcccttccaa atgattctgg attctgggta
    10681 ctttcaagat ttagtggatt atcagttaaa gatactttaa actcttggac aattggagga
    10741 accattgctg gagttgtagc atttataatg gttttattgc ttagtgttat aaatggaatt
    10801 ataccacttc caggtctata aataacaaac tattgtttat attatataaa ttacatttag
    10861 actatacaaa ttacataaag gggcgtttta aatgagagaa gtaaaaccaa ttagcataga
    10921 tatacttaat acttttaaac aagtagatga ggacagatta aatgaacttc ttgcagatga
    10981 gcttaagcat ttagatagaa aaattgttgt attagatgat gacccaacag gtgtacaaac
    11041 agttcatgat atttctgttt atactgattg ggataaggat agtatggaac aaggttttaa
    11101 tgagaaaaat agtatgtttt ttatacttac taattcaagg ggatttactg ttgctcaaac
    11161 tacaaaagca cataaagaaa tttcaaagaa tattgtggat gtatcaaaga aagttaataa
    11221 ggattttata atcataagtc gtagtgattc tactatgaga ggacattatc ctgttgaaac
    11281 taatttatta aaaagcgaag tagagagatt atcggggaag ttatttcagg gtgaaataat
    11341 aatgccattt tttaaagaag gtggtaggtt tactatagat aatgtacatt atgttaaaga
    11401 aggagaaata cttgtaccag caggaatgac tgaatttgca aaggataaat cttttggata
    11461 taaatcatct gatataggtg agtggtgtga agaaaagaca catggaaagt acaaatctag
    11521 tgatatgata tatatttctt ctaaagaact tagagagcta aatattgaag ctataacaga
    11581 aaaacttaaa aaagctgaag gattcaataa aattattgta aatgcaaccg attatgtaga
    11641 tgtaaaggta tttacaattg cgtttatacg agcagtaaat agtggtaagg aatttatgtt
    11701 tagaagcgct gctgccataa caaaagtact tggcggagtg agtgataagg aaatgcttac
    11761 taaggatgag ttagtatcaa aaggtaatac caatggagga attatacttg ttggttcaca
    11821 tgtgaataag actacccaac agttagaaga acttaaaaat tgtaaatatc caatagaatt
    11881 tatagaattt aatcaacatt tagttcttca ggaaaatggt ctaaaaaatg aggtaaaaag
    11941 agttataaaa gttgtagagg aaaaaataag cagtggtaaa actgttgctg tttatactag
    12001 acgagagcgt tttgacttgg atacgaatga taaagataaa cagcttatga tttctgtaga
    12061 aatatcagat gcagttacca gtataattgg tatgcttaat gtaagaccaa attttattat
    12121 agctaagggt ggaattactt ctagtgatgt tggtactaaa gcactaagag taaaaaaagc
    12181 tacagtaatg ggacagataa aacctggtat accagtatgg atgacaggca aagaaagcaa
    12241 atttcctaat atgccatata taattttccc tggaaatgtg ggagagatta gcacacttag
    12301 agaatcagtt gagatattga tggggtagta tattagtgta ttgaagttta aacgcttaaa
    12361 tttactgtgt taaaagtaaa ataaactaaa attataaatt aagattaaaa ataatagtat
    12421 attaattagg gtttagagta ttttacaaaa aatattctaa accttaatct tatgtattag
    12481 tatttttatt atttaactta tgtgtttatt ttattattta tcttttttaa ttgatttaat
    12541 attttctttg attttattta aaatatctgt atgcttatta gagcttatgt tggggaatgc
    12601 tttgattata cgtctatgaa gtaatttgtg gttagacagc aaagtattaa gtttattttt
    12661 tagctcatca atacgatttt tagcatagcg atagttttct ttttccttaa gtatttcaaa
    12721 tctatcttcc aaagtatcca gtctattttc aactaaagat tcaagtttgt tttctatagt
    12781 ttcttgtgta ataagtttgt agtattcttt cttatctttt aattccttaa ttataagatt
    12841 gatttgtttt aacttaccat ttaattgtaa aattgtatgg actgtgataa ctaaatctaa
    12901 aacaaaataa atttctatag atatagcaaa tataaatagc acatttttag agatagagtt
    12961 aataaagtca accacaatag gatgtactat aagcattaca atcaatgata atacaccaaa
    13021 cataagtgag ttttccagac aaactcttcc atgaatatta aatttatgtt tagaataatc
    13081 ccaccaagtc atattaaata ttttttctaa aataaagctc gtacaatact ccattatgct
    13141 agttataatt atactaaaca aaaataacaa aggaatattg tgtacaaaag gagtcaaggt
    13201 agcaactatt gctaatgctc caaatccata tatagggcaa aatggaccat ttaaaaaacc
    13261 tctatttaca aattgttttt gtaaaactga acaatatgta gtttcacaac accatcctat
    13321 aaagctataa attacaaaat aaagaaattg aatataaaat gtactcataa gcacctcatt
    13381 tctagttagt ataacactat atactcgata ttttattttt atgattaatt tgctaaattc
    13441 aatttacata ttgattatac caatttatag aaatttatca aatttaatta cagttagaac
    13501 attataaaca tggttataat aatgaaattt tatttaaaat aaataagggt gtcaagtata
    13561 atcaaactaa tagttgtaga tactctacac tatgttagtt taattacatt tgacaccctt
    13621 atatttatac tatgactatt tacattcgaa actagaacaa catgtttcaa tataaaggtt
    13681 tactctatca gtttcaggag caaccaatat attatcaagt gtacataagc taccatcttt
    13741 gttgtattta caatttttta cagtacaaac taattcctca caatttctat tattaacgtt
    13801 gctagataaa ttactataaa tagattcatc taaaaatgaa ctacaacaag tatgtctgtc
    13861 attgtgagct ttttcaccat ttataaaaat tttatctgca taacatatat ggctgttgtt
    13921 atgtgaacag ttaattacat tacagtttat tctttccaaa gttattacct cctaaacgat
    13981 tatttattat aaattatgtc catataatta caagaatata accattaaga gaaaactacc
    14041 ttttagaaaa tatctattct tagagtaatt tgaaatataa atatattttc ttctaaaatt
    14101 tacctaaatt gtataaaaac ttacagcttg gagaaaataa tagaaaaagg aggcgtaatc
    14161 aatgtttgaa aagaagaaaa aagaattatt tccttggaaa atatctgcct taatactggt
    14221 tggagtattt gtattaagta gcggagttta tatagggaca agattaaaaa ataatggagt
    14281 tcaaactagt aaagttgtaa gtgctagtgc gaatatggac gaaaagtcaa aagaagcttt
    14341 tggattaaat aaaaattgtg aagtttggct tcaaagtgaa ggcgaaaatg aaactaacta
    14401 taagagaaca cttacaatgg ctgggatagt tccagagtca ttattagata agacaaaatc
    14461 agaaatagta tcatatttta aaaaagaata tccaactaaa aaaataaaga gtatggataa
    14521 aaatgaaatc atattggtag aatctaaata tagtgataat aaagatgtac aagcaatgaa
    14581 cgctactata aaaggtaaat atactattga aaatgataat ggaaatatag cactatataa
    14641 atatgatgat agtggaagta aaacattagt agaaaaaaca aaaataagag tagattcact
    14701 tcctaaaaca gttcaagatg aaatcaaaaa aggtgtagtt atggatactg aagaagaggc
    14761 ctattcaaga ttagaagact ttgcaagtta atagtaaatt aatattattt caagttaaat
    14821 actaagtaag ttaataataa ataatttaat attaaataga ttagtattaa aattgtagtc
    14881 acatttaatt cctataaaaa tacaataatt tatttgtaat aaatataaaa gttatattga
    14941 ggtaaaatct tgctttgata taactttttt atttgatttt atattttaca tagagcattt
    15001 tatgatttgt taatattatt tatgatataa tgatttagaa cataagtttt tatgagaaat
    15061 acattttggt atttctttta tttttagggg gaattttaaa aaatgataat attggggatt
    15121 gacccaggta tagccatagt tggatatggt ataattgaat acaaaaatag caagtttaaa
    15181 gtaatcgatt atggagcagt tacaacacct gcccatatga atatatcgag aagattggaa
    15241 cttgtgtata aaggaattga tacaatagta aagaattaca atatagatga agttggaatg
    15301 gaagaattat tctttaacaa gaatgtaaaa acagctataa cagttgcaca agctagaggt
    15361 gttactatgc ttgcatgtgc tcataatggg aagcctgtat atgaatacac tccacttcaa
    15421 gtaaaacaag gtgtagttgg atatgggaga gcagataagg cacaagttca acagatggta
    15481 acttcatttt taagtctaaa aaaagttcca aaaccagatg atgttgcaga tgctttagct
    15541 gtggctattt gccatgctca ttcaaacaaa cttgaaaaaa ctctaaagaa tataggtggt
    15601 aagtatgtat agttatataa aaggtacagt agaagaaatt tatatagaca gtatagttgt
    15661 tgaaaataat gggataggat ataaaataaa tgtatcatcc aatacaataa tgaatttaca
    15721 agtgggagaa gccacaaaaa tatatactaa attaattgta agagaagatg atatgagtct
    15781 ttgtggtttt gtaagtaggg aagaacttaa gatgtttgaa ttactaacat ctgtatctaa
    15841 aataggacct aaggtggcgc tttcaatact atcatttgca tcatcagcac agttaggagc
    15901 atatatttta agtgaagaca ttggaaaatt atccaaagct cctggtgttg gtaaaaagac
    15961 agcagaaaga atcgtcttag agcttaagga taaggtagac aaaaataaca tagagtttga
    16021 accaacgtta ttatcacaaa aacctacctt gatatcacaa gatgagtctg tagatgcact
    16081 tgtagcttta ggctatactt tgtcggaatc aaaagaggca gttcaaaaat gtaaaaaaga
    16141 tggtatgaat acagaagcta ttataaagaa agctcttaca tatataatga gtaaatcctt
    16201 gaaatagtat ttggatttta taatatttgg attttaaaac aatatttaag gagtttatgt
    16261 aaatttgaaa atatataaag tagattttca aaagtacgag aggaggggta taaatgcaag
    16321 gttttgaaga tgaaaatagg ataataactt ctacaatgaa gatggaagat atagatatag
    16381 aaaacagttt aagaccaaaa actttagaag attatttggg tcaagaaaaa tccaaagaac
    16441 aacttagtat atttatagaa gcagctaaat cgagaaatga gcagttagac catgtgcttt
    16501 tatatggacc accaggtctt ggaaaaacta cactagcaag tataatagca aatgagatgg
    16561 gggtaaattt aagaattacg tcaggacccg caatagaaag agctggagat ttggcagcca
    16621 tacttacgaa tttaaatgaa aatgatgttt tatttataga tgagattcat agaatcaata
    16681 gaagtgttga agaagtttta tatccagcaa tggaggattt ttgcctagat ataataatag
    16741 ggaaagggcc atctgctaga agcataagac ttgaccttcc taaatttaca cttattggag
    16801 ctactacaag agctggtatg cttacaaatc cacttagaga tagatttggt gttatttgta
    16861 aattggatta ttatacagtt gatgaacttt caaaaatagt acttaggtct tcaagcatct
    16921 tagatgcaga gatacagtct aatggagcat tagaacttgc aaaacgttca agagggactc
    16981 caaggatagc aaatagatta ctaaaaagag ttagagattt tgcacaagtc agagctgatg
    17041 gaaaaataac tgataaggtg gcaaaagatg ctctggaact tttaggagtc gatagtttgg
    17101 gtctcgattt tgtagatgag aagcttctta tgactataat agaaaaattt agaggaggac
    17161 cagtgggttt agatacattg gcagcttcta ttggagaaga tagaaataca atagaagatg
    17221 tatatgagcc atatttgctt caattaggat ttataaatag aggtcctaga ggaagagtag
    17281 ccatgccatt agcatatgaa cacttaaaaa ttccatatcc taatgaaaaa taaaaataga
    17341 ttatacgagt atttataaaa taaaagagtc attaaattaa aatatttcta aaatggctaa
    17401 aaattcaaat atatccacaa aatggtaatt atatctgtag atactgtgga taaacacgat
    17461 aaaaattgtg tgtattgtat ctatatattg tggataagac atgtatatcg tggaaaaata
    17521 tctatatatt gtggatatgg tgtctgttaa aaatagcaat ttcttgatag attatggtaa
    17581 tattgtggaa aataagttgt ttttttgata ttattgtagc tggagaaatt ttaagagagg
    17641 aagtttaaca ttgaaaacaa gtgattttaa atttgactta ccacaggaac ttatagctca
    17701 agttcctata gaagatagag ctagctcaag attgatggta ttagataaag agacaggtaa
    17761 tattgaacat aaagtattta gagatataat agaatattta aatccaggag attgtttagt
    17821 attaaataat actagagtta taccagctag attaatagga gagaagcttg aaactggagg
    17881 taaaatagag tttttattat taaaaagaac agaggaagat acttggcagg ctttagtaaa
    17941 accaggaaaa agagcaaaag tagggactaa attttctttt ggaaatggaa agctaattgg
    18001 agaagttgta gatttatcag atgaaggttc aagaattata aaattccttt atgatggaat
    18061 ttttgaagaa atattggatg aacttggaaa tatgccacta cctccatata tcactgctag
    18121 actagatgaa aaagaaagat accagactgt ttattcaaag cataatggtt cagcagcagc
    18181 acctacagca ggattacatt ttacagaaga attgttaaat aaaataaaag aaaaaggtgt
    18241 agatatagct tttgtaactc tacacgttgg tttaggcact tttagaccag taaaagtaga
    18301 agatgtttta aatcacaaga tgcattcaga atattatatg gttagccaag aagcagctga
    18361 caaaataaat agagcgaagg aaaatggaaa caatgtaata tgtgttggta ctactagttg
    18421 tagaactata gaatcagctt gtaatgagga tggaaagatg aaagaaacta gtggatggac
    18481 agaaatattt atatatccag gttataaatt taaagtttta gataaactta ttactaattt
    18541 tcatttacca gaatctacac taataatgtt agtaagtgct atttgtggaa aggataatgt
    18601 tttaaatgca tataatgagg cagtaaaaga aagatataga ttcttcagtt ttggagatgc
    18661 tatgattata aagtagggag gtaatgaatg catagtttac aaaaacaaaa aaagaataac
    18721 cctatattaa agattgcttt tatatttgaa cgtgttttag cagtagtagt tctaatagca
    18781 gtatttttag gaactataga tgttctaaga cttatgtggg gagcatatat agttgatttt
    18841 caaaatccag tacaatacag tcagcttaat gattttttag cacaaatatt acttttagta
    18901 ataggtgttg aacttgtagt aatgctatct cttcatatac caggagcatt tattgaggca
    18961 ttactttacg caatagctag aaaaatgttg ctactgccta aaaatgaagg tatgatagat
    19021 gttttaatag gagttatagc tatagcagga ctatttgcta taaaaaagtt tttagtaaca
    19081 aaagacaaga gtgctcttaa tataatgagt attcatgatg aagaagcaat taaggagcaa
    19141 cagaacaaag aagacgaaga taaatctatt tagacaataa attatatgaa tagcttatta
    19201 caaatatatc ttaagaaata atgagaaata aatatggtta aggagaactt tatgtacgca
    19261 gtaagatatg aattgataaa gacttgtaag cagagtggtg caaggttagg aagattacac
    19321 actccacatg ggattattga aacaccaata ttcatgccag ttggaactca agcaactgta
    19381 aaatctatga caccagaaga attaaaagag attggttcac aaataatact tagtaacaca
    19441 taccatttat atatgagacc aggtcatgaa cttataaaaa gagctggtgg tcttcataag
    19501 tttatgaact gggataaacc aatacttaca gatagtggag ggttccaagt atttagctta
    19561 gggcctttaa gaaagataaa agaagaaggt gtagaattta ggtcacactt agatggttca
    19621 aaacattttc taactccaga aaaagctatg gaaatacaaa atgcattggg ttcagacata
    19681 atgatggcgt ttgatgagtg tgcaccatac ccatcagata gagaatatgt aaaaaattct
    19741 ttagaaagaa caacaagatg gttaaaaaga tgtaaagatg cccataataa taccgacaaa
    19801 caagctttat ttggtataat acaaggtggg atgtataaag acttaagaga acaatcagca
    19861 aaagaaataa ctagtattga tttaccagga tatgctattg gtgggcttag tgttggagaa
    19921 ccaaaaccac ttatgtatga cgtgctagag catacaactc cacttatgcc acaggataaa
    19981 ccaagatacc taatgggagt tggtagtcca gatgacttag tggaaggtgt tataagagga
    20041 gtagacatgt ttgattgtgt cctacctact cgtatcgcta gaaatggaac tgcaatgact
    20101 agccaaggta aagtagtagt tagaaatgca acttatgctg aagactttac tccacttgac
    20161 cctgaatgtg attgttatgc ttgtaaaaac tattcaagag cttatataag acaccttata
    20221 aaagcaaatg aaatactggg tgcaagatta ataactactc ataatcttca ctttttatta
    20281 aatttaatga aacaaataag acaagcgata atggaagata gattacttga ttttagaaat
    20341 gaattttttg caaaatatgg atatgaaata taggttttgc actattaatt ataatcattt
    20401 taatatataa tattcaatag tactcaaaga tagagaaagt aaattgttat ataaacattt
    20461 attatgattt acaaaagagt ataatttaca aaggagtgaa aaattaatgc cacagcaaca
    20521 aataattatg agtataggtc tatgggtagt agtaatcgca atcttttatt tcctaatgat
    20581 tagacctcaa aagaaaaaag acaaacaatt aaaagaaatg agaagtagcc taagtgtagg
    20641 agacaaggtc attacaatag gtggaatagt agctaatgta gctaaagttg aagatgatgt
    20701 tgtaatatta gaattaggac caaatagaac taaagttcca tttgaaaaat gggctatagg
    20761 aactgttaaa tctaaaaaag aagaaataga agaagactaa attagtaatt taaaagcctt
    20821 ttctcgaata tatattaatt tgagaggagg tttttttatg ggaaaatcta attatatttt
    20881 taaaggtcta ggatatgcat atataataac tttggctgtt ttattagtgt ataacttatt
    20941 tttgacattt acagatattg gtggagataa tataactatg gtctcatcat ttataactac
    21001 tatttctgca gctataggag ggttttacac ttcaaaacac atgaaagaaa aaggacttat
    21061 gtatggactt ttagtaggac ttttgtacat agtatgtatt tttttgactg tgtttttagc
    21121 acaagaaaag tttgtatttg aagtagggat gatttataag ttattgctaa tatcagcagc
    21181 aggaggcatt ggaggcgtat tgggtgtcaa ctttaaatag agtttatatt aaagtagttt
    21241 tatgatataa tcaataggaa acaattagaa atggaggcgt tgaaaatgga aaataaacat
    21301 gtaaaaactt tatctcaagc tactttaaag caaagtgctg caaaaggtgg atgtggagag
    21361 tgtcaaactt cttgtcaatc agcttgtaaa acttcttgta cagttgcaaa tcaagagtgt
    21421 gaaagataga aaattattga tttagttgtt tgtaagaggg tatctcaaag tgattctttt
    21481 atcattatga ggtatcctct tttattttca attattatat aaaaatatat attctactta
    21541 tgtaaaatta aatttgattt cttatcgttt aattatgcaa aaatatctaa tcatataaga
    21601 gcatttattt taaagtagct actcttatat tttatttttt atcaattaca tgtattagaa
    21661 taatttttaa ttttaaactc taatttatga tgattttata atatgttata tattttaata
    21721 tatggaggta gatattaatt tagtgatata tatttaagta ataagagcaa agcaaaaatt
    21781 agtgcatagt agtatataaa aatggagttt gaatactttt gttagtatat gattgtttag
    21841 tagaaaatca ctataaaata gggatttcta tctttgagca taattataga gagctaagta
    21901 gggggaaggg gttcaagaag atattattag tgtttgtgtt agtaaattat gtaaacacat
    21961 aaaatatatt gaaaaataat attatatata atattattta tgtgtgggaa atacgaatat
    22021 aaaaaataaa aaataatatt cggaggacat aaatatgtta agcaacaaaa agagaagtat
    22081 ggcaatagta atggcaggtg ctacagttat gagtgcagca gcaccaatat tcgcagacaa
    22141 tactgtgaca gaaaatgttg ataaaaatta cacagtaagt gcgaaagatt ctgctaaact
    22201 aatcgaagag gttagaaaag cattagaagt taagtttgaa gatacaaaag caggagcaaa
    22261 tgtaaatgat agagtttacg atataaaagt agacaatgta aacttaacta atgcaactca
    22321 attacaaaat aaaataaact ctttaacaga agggcaaagt ttaaaagtta ctattcaaga
    22381 taaaggacat caagtgttag gtggaaaagt agttgactat aaaattgaaa actacaaaac
    22441 tgctcaagaa atagtagatg cagttaatgc ttacaatgca actttagcag aagattctga
    22501 taacaagtta acagcaacta taaaatctac aaatacagtt gaagtaaaaa gagcaaaaga
    22561 ttcagcaaat gttattacat taaatgtagg agaccaacat ttagatttct caaaagtgat
    22621 aacatcagaa gaaggtactt ttgaaggtta tgaaaagagt tatagtgaca tagattcaaa
    22681 agaattacat acgataacag ttaaaaacgc agatttacaa gacatatcag cagaagaatt
    22741 atttgatgga attagattaa ctacattagg aagagaaata gttaataaag ttaaaaatgg
    22801 atatgcttta acatttgaaa atgaagcaat ccttactcaa gaacaagaag atagtgatga
    22861 taaagataaa ccagaaaaat caagctttga tatagtttta agcaaggcaa atgaaaagtc
    22921 agaaacaata agtgtttcaa gtaaaaacca taagttagtt agagacttac acaaagtatt
    22981 aactgatgta aaagatggaa aagaattaaa agtagaggtt ttatctggtg attcaagatt
    23041 tacaacagca gtagaagtta gtaaagagag attcaaagat ggagaagcag aagctataat
    23101 tttagttgga gaagatgcta tagttgatgg attagcatca gcaccacttg cctctcaaaa
    23161 aaatgcacca atattattat ctaaaaaaga ttcactacca tcagaaatag aagctgaaat
    23221 attaagagta cttggaagta atctatcttc taagaaaata tatatagtag gtggagaatc
    23281 taaagtatca aaagaaactg aagaaaaact ttctaaatta ggtgtaagta aagttgagag
    23341 agtttctgga gaagatagat ttgaaacttc tttagaaata gcaaaacaat taaaagatac
    23401 atttaagact gcttttgtag taggtggaaa tggagaagct gatgctatga gtatatcagc
    23461 tagagctgct caatttggtg ctccaataat agttacaggt aacgaattag atgcaaatgc
    23521 tgaaaaatta ttaaaaggaa aagaattaga aatagtgggt ggagaaaatt ctgtatcaaa
    23581 agaagttgaa gacaaattag ttgatataga tttaaataat aaagttgaaa gattagctgg
    23641 agaaaataga aaagatacta atgctaaagt aatcaataaa tactatgcag gtgcaactaa
    23701 agcatatgta gcaaaagatg gttatgtagg tggaaatgga caattagttg atgcacttac
    23761 agcagcacca cttgcagcta gttcaaaggc tccaatagta ttaactacag aagaactttc
    23821 taaatcacaa gaagaagtag ttgagttaag acttaagaat gctactaagt tagtacaaat
    23881 aggtgaagga atagctaaaa acgctattga aaaaatagca gaaaaaataa acttatttac
    23941 taagaactaa taagatatag gaattaatat taaaagttta tttagataat atatgattat
    24001 acaatgcgtt aatatgtaag acatagtgta gatattataa aatatacaaa taacaagata
    24061 aaataataaa aataaggtgt ctcatttaga attagattga gataccttat tttatttttt
    24121 gattataatg tggagaaatt catattgcaa aaattattat aaaaagatac ttcttataat
    24181 gattaaacat attactaaca taaattattt tgaacttata acttaattaa ataaaataaa
    24241 ttataatgtt ttgaatttat agagaataaa aactttaggt atattgtttg agttgtatgg
    24301 ataactatgg tatcatatat aaaatatggt aacaaaattg taacttttga ttaaaaataa
    24361 gtatgagtac taataaaaaa tatgaaaagt acattggggg tagaaaataa tatgaagaat
    24421 agtaaaaaga tattagctat aggacttaca ctatttttag taatggtaaa tactcctatg
    24481 gtaaatgcgt tgacatcagt tgagcaaata aaagggaatg acagatatga gacagcagca
    24541 aaaatagcag ataagcaaaa ctacaataca gcaatactaa tcaactcaga taatagctta
    24601 gcagatggtc taagtgcaag tggtttagct ggagccttaa atgcgcctat tttaatgaca
    24661 aagcaaaatc agattccaaa cacaactatg gaaagattaa acaaagcaaa gactgtgtat
    24721 ataataggct cagaatcaac aataagtaaa aatgttgaga atcagttatt atccaaaaag
    24781 aaggttgtac aaagaatatt tggtgaaaat agatttgata caagtataaa aatagctgaa
    24841 aaaatcaaag aaattaagcc aatagataaa gtaattatag ccaatggatt tacaggagaa
    24901 gcagatgcga taagtgcatc accagtagct gctagagatg gagtacctat aatacttata
    24961 gatggaaata gtgtgggatt tgacacgaca ggcttaaaga gttatgcgct tggttctagt
    25021 gaaataatca gcgacgaatt agttaagagc acaaattcta ttagattggg tggcacagat
    25081 agatttgaaa ctaataagat agttatacaa gagttttata aaaatagtaa agaattttat
    25141 ctaagtaaag gcttgcaatt aacagacgct ttggtcgcct ctacaatagc aaaaaatgct
    25201 cctgtagttt tagttgaaaa tggcagtaac aagagtattt taagtggtgc agacaaattg
    25261 actgtactag gaggcataaa tcagaatgtt atcaagcaat gtataaatca agcttcacca
    25321 aatcaacaag ggttatatta caatccaaat gatagagcat ttaaagagag aataaagggt
    25381 aaagtatatg ctcttacaaa gcagtataga aaagataatg gagtaagagc gttatctgta
    25441 gcaagcagat tagagggtct agcaaatgat tggtctaatt taatggcaaa taagaagact
    25501 ttatctcata cgataaatgg aaaaaattca tattctactt ttttgaaata cttagattgg
    25561 agtgagatta aacctggata tatagcagtt caaggtgaaa atataattaa atataaaatt
    25621 tcagataaac ctgtatatac aaatagagat gcagatgata taggaaactt tatttttaat
    25681 gagtggaaga caaatccaga agaaggaact aatatgttgc ataaagggta tgaaataatg
    25741 ggatttggta tagctataac aggagataag aatctatatg ctacacatga attttatgga
    25801 agatataaag aataagaaaa tatacacaaa attatgcttg taaggaagct atataaataa
    25861 ttaaattata atggaaaata acatttatat taatttatta atataaatgt tattttttta
    25921 taatttaatg taaaaaaatt gtattaaaaa gtttaaatat agtataaaat gggtaagaaa
    25981 gtagtgaaaa ttaaatggca aaattaggga aatctaatga cgcaaaacta tagggattaa
    26041 agcttttaaa gccatatcag ccagttgcta aaaagagtaa agtcttttta ttttataatt
    26101 aagattctct ttgagtgtct ttttttattg tctgaaactt atagtattta aattcatgaa
    26161 aaattagaga tttattaagg gaggattgtt gtttcatgaa aaaggcaata tcttgtgtac
    26221 tagcagtatc tatgtgtagt gcaccactaa atgtttttgc agaacctata ttagagggga
    26281 agctaagggc agttgaaaaa tcagttacag aaaagttaag ggggaatctt gaagtagatt
    26341 taaatttttc actgccaata aaaaatagcg agtcagaaag tatgactaat atgcagttac
    26401 gattaaaaga tgatagtaac aatagtggaa taataaagct tggagaaaaa gattcaggaa
    26461 cagtaaatat tgggacagat aatatagaat atactataaa aaaattatct gcaagtagaa
    26521 gtgaaataaa aaataaagat gagaatgtat catattataa tattgtattt aataatttac
    26581 ctgttggaaa atacaatata gaagtctctg gagctggatt taagaacaaa gaaattaaag
    26641 acattgatat atcaagttat tcacaaagag tcttattaag caatagagca agtgtagata
    26701 ataaaaataa acctttaaat tatgaattat tcttaatggg tgatgtaaat ggagacggta
    26761 aagtagataa gagtgattat aataaggttt tagagaatat agattcaaat aaaagagaat
    26821 ttgatttaaa tagagatgga aaggtagata ttgttgactt agattatgta cagaaaaatt
    26881 taggacaaag tgaagatgca aaaagcctag aaagtatagt atctaccaat cctatagtag
    26941 atacaagtaa ggttgaatta aaaggaaata gtgatgtaga tattaatggt aatgtagaaa
    27001 atttatttag tggagaaaat aatggagtta caatatcttc aaaaaatgat gaaatatctg
    27061 aggaaaaacc agcagtaatg gatatagctt tatcagaagc acttaatatg gaagtcatca
    27121 atataaaagc tccagaaggt actgctccag caaaaggaat agttgaggtt actgacgaag
    27181 atggtaatgt tcaacagatt ccttatgaaa ataaagaata tatgaaaaac ttaaaagata
    27241 aggagcaaca agaggaagta aataacgaac aagaagaagt aaatcaagaa gaagtaaata
    27301 ataaagatga aaataaaaat cagactgata ataattcaaa taataaagat gaaaataatg
    27361 ataaacaaca ggaaaatagc gataaacaag aagtaaactc taataccaat caagataaaa
    27421 ataatgataa agaaaattca tcaatggata aacctaattc agatgaagat actccaaaag
    27481 aaggggataa tatcagtaaa gatgataact ctacaacatc tacatatagt agggcagcat
    27541 tagaaacata tacagatgtt caaaatagcg atatagtaat aaatcttggt aaacaagtag
    27601 cagtaaaaaa gataactata aaaataacag ctacaacagc aaacgataga aatcttgcag
    27661 aaatatcaaa agttgaattt ttaaacaatg tatataaaga aataccaaag ccagagatga
    27721 acatacctaa aataaataaa atatcgacta gcactgctgt tggaaatgaa aaagtatctt
    27781 tttattggaa taatgaagta aatgtatcag catacgaact tatactagat aaaattgata
    27841 gtaagggaaa agtattatct actaaaaaat tacaaactag taaaaataca atagaagtta
    27901 gagatataga agcatatgga ctatataggg ttagcataca atctttaaat ggagattggt
    27961 ctagtggtta taaagatgca acgccagaaa acttagatgg agtaccagaa aatgtagact
    28021 caaactataa acctatacaa tttagcccag atagcatatt agaatttcaa gttgttccag
    28081 acacaaaacc agaaccacca gaaggtataa atgttaaagg taaatttaaa tctcttgatg
    28141 taagctggaa aaatcataaa caagctaaag actttgactt gtactataaa gaaaaaggct
    28201 ctaatgggtc ttggataaaa tacaatgata agcttattcg tgggacaagt ttaaaaatag
    28261 aaggtcttaa ggataacaca acatatgaag ttagaatgac agctactaac cacttgggaa
    28321 ctagtggaat gtctaaaaca tatataggta caactgaaag catagatgca ccaacaacac
    28381 ctaactatag attaattaat actcctaagg agaatggtgg atttggaata ccaacaaatc
    28441 acattgtaga tgttgtttat ccagcaggat atgacaaaag tgaatatagt gataaaaatc
    28501 catttgataa attcaatgta gtagatggag acttcacaac acattggaca ttcccaacat
    28561 ataatgcagc tgagggaacg aatagaggac caataataac ttttgataaa tcttatacta
    28621 tggatacttt tatggctaca cctcgttttg atgtttctga taagacaata aatgactttg
    28681 agatacgata ttgggatgaa aatggtcaat tacacaatct gggggatgtt ccttttgaaa
    28741 caaagacaga ccctgtaaat aataataagt atgtaatggt tagattaaaa gaaccaataa
    28801 ctgctactaa gatacaagta agtgtttgtt catcttattc atataagtct aatatatcag
    28861 aacttaagtt ttatgagtat gacagtatag aagatgatgt aagaaatcta tttatggatg
    28921 acctacaagt tgaattaaaa gaagatgtaa ctcaagaaaa aataactgaa ttaaaagata
    28981 gattaaatac tccagataaa gctagtggag aatatcatcc atataagaca gttattgata
    29041 gagaattaaa attagctcaa gacttatata atgatagagc cacacttact gatgtaacta
    29101 ctgtaaatca agaaataaat aaatcaggaa aatataaaga taaaaacgga cagtatactg
    29161 taaattccaa taacttaggc atgcaaaatg actggcaggc attaggagta gctgctagag
    29221 caggagatga aataacagta tatgttggaa gtaaaagtgg aaaaactcct aagttgatat
    29281 atacacagta ctatggagaa tctggtgcat ataagagtgg agaaataaat cttaaaactg
    29341 gaaaaaatgt aattcaatta agcaaacttc atagtttaga tatagaatgt ggaggaagtt
    29401 tatacataag ataccctgaa gatactccaa gtggaggaga tataaaagta cgtgtagcag
    29461 gagctactaa gataccacat cttaatctaa atggaacaat aaatgataag agtcctgcgg
    29521 gagtttctga atctaagaaa aagataaaag catatataga agaattagct aaatataaag
    29581 atgctgtaaa aggagaacca tattatccag gaacaaatat tggtaattca tatgaatatt
    29641 cagaaaaaac tggtgtgtta aacactacag atattgaaag tgataaagta acattaaatg
    29701 ttcctgcaac agctgtatat caaggaatat caaaaggaaa tgctgattta aatacacaag
    29761 tagatagatt atataatagt atgcttgcat gggaacaaat aatggattta gtttactcag
    29821 aaagaggagt atttaaaaca caagatttag atggtaatgg aactgtagat gataatgaat
    29881 ttaacttaac taaaaatgat atggctccaa aatctcgtat gaacataaaa taccaaagaa
    29941 tgtttattgg agcatttatg tatgcttctg gattacatgt aggagtagaa tatggttcag
    30001 ttccagggct tatgaatgga gtacctttcc aaatagatga tagtggaaaa gctacaggag
    30061 gaaacttatt tggatgggga ataggtcatg aaataggaca tgttacagat attggaaaga
    30121 tgacatatag cgaaactagt aacaatgtac ttgctttact tgctcagacc tttgatgata
    30181 agacacattc aagacttgaa ggttcaacaa tggataagat atatgagcat gtaacttcaa
    30241 atagcttagg tataccaagc aatgtatttg aaaggcttgg aatgttatgg caattacatc
    30301 tagcttatga tgatgatttt acgggttcaa tgttaaagaa taactcagat gctgatttaa
    30361 gtaatgatac attctatgca aagatttcaa gaaaatacag agcactttca agtagtgacc
    30421 caattaatag tttaccaaaa gaccaaatgc tagtagcaat ggcatcaagt gttgttgaaa
    30481 aagatttaag agattacttt aaggcatggg gagtagaaat tacaccagaa ttaaacagta
    30541 taatggatag taagaactat gaaaaagaat caagaaagat acaatatgta aatgacgaag
    30601 ctagaagaaa gattttaaat gaaaatatag ctagtatggc aaaagatact aaagtaagtg
    30661 ctagtttttc tgatggaata caaagtggtt ctctagttaa atctaataaa atatctatag
    30721 acctagatgt agataaggat aaagataaga tactaggata cgaaataata agaagtgatg
    30781 gaaattattt agatggtgaa aatggaacac aggtaaaata cagaacagtt ggatttgtgg
    30841 atgcaaaagg aaatagtaag gccaaattta ctgatagtat atctcctctt aataacagag
    30901 catttacata taaggtagtt gcatatgatt atcacctaaa tccaacagaa gaatttgaag
    30961 ttggcactgt aaaattatca gatgaaggga aaataaataa atcagcatgg tcattcataa
    31021 caaatactgt ttctgacggt gatgttagaa ctgaaaatga ctcacatgga ccattacaaa
    31081 atcctgaaat tgataatata aaagataatg atgtaagtac tacatataaa ggaaagataa
    31141 taagtaaagc agagtggaac aaagaccctc aaaaagaccc tgatataaat gtagaagaaa
    31201 atccatatat aatagtagac atgaaagaaa cattacctat agtaggacta aaatatacaa
    31261 aaccagaggc agaaactagg aagttctcat taaaaggatt atttaacttt agaaagaata
    31321 ctagcacaac atacaatcct ttaactaatt acaagataca agtaagtaat gataaaaaga
    31381 actgggaaga tgtaagtcaa ggaacttttg aatatggaca agatttagtt ggtggaggaa
    31441 aagaccaaga taatgaagct agagttacat ttaataaaga tgataaactt tggacatacc
    31501 aagctagata tgtaaaacta atctcaaaca ataagtctaa tatagaagtt gcagaattag
    31561 atataatagg acctccaggt gataatatag aaattggcac aatgaataat gcagaccaaa
    31621 ctcgtactaa tggaattgga aagttagcag aagattatgt atatcaaagt gatgacccta
    31681 gcacaagtga agatgaaaca ggtaagattc cagcaggttc aataattatt acaggtgaat
    31741 acagtggaaa tccagcattt aatttaccac tacttataga taaaaacaat aagactatat
    31801 ctggagaagc acttttattt gcagaagttc cagaaaaagg tgaattaggt gaaatcagta
    31861 aaggtacatg ggtttactat atgccaaaag aaaactttga ttctttaagt gataaggtta
    31921 aggctgaact atatagatac aatgaccttc aaggagatac gccagtaggt caaagatttg
    31981 taagtgatac aatgtatgta cctgtaggag ctaagaatta tgatgagtta aagacaataa
    32041 gtcttactga tagtaatagt aaagctagaa aagctacaag aaatgctatt gatgtcagta
    32101 ataagaaggt tataactgta agcaataaag taaagggtaa tattgttaga gataaatagt
    32161 aggtggaact ctaaaaacgt aaaaatacta atactaacat tgtatatcta atatgattag
    32221 gtactagaat agttttaaaa tagtagatat taaaagcaaa gtatataaat gtaactataa
    32281 gtttagggta atttataaat taaatataaa agctaggtgg ataagtaaat ttatccactt
    32341 agttaatgat agataaggac gggtgttaat gagtaaaaga aaatctttta taagaactat
    32401 agcagtatca actatggcag tagctgtaac tggtagtgtt acatgtgcat atgcagctcc
    32461 agttttacaa ggaacaaaaa cgtatgagaa agtaaatact atagatatat ctgtggactc
    32521 agtagaaaac atagtatatt catttcaagc cagtataaaa gtacaaggtg aggttgaagt
    32581 agtagataat gagcagaaag aaaagattac ttggtctgat aatataaaat ctcagataaa
    32641 aagtggaaat gcaaatgcta cttgtagagt agaatacaac aaatcaagta atacaactac
    32701 attagatata tatgttacat caaatgaaga tttactagac ggaaatagat tgaatatagg
    32761 aagaatatct gtaaaaaaat ctggcagtaa ctcaaatgct gactataaag ttttaggaaa
    32821 aggaacaagc gataaaccag ctttaaaaat tgtaacatat aacaacaaaa cagtggatta
    32881 tgaaaatata aactctgatg aaggattaat atttaccctt attaatgaga gtgaagtaaa
    32941 accaattggt ggaactggtt ctagtaaaaa tgaccctgag aagtataagg tagagaaaag
    33001 tgaagcactt gaatatttat taaacaatat taggataaac tattctattg ttagtaaaga
    33061 aacacaagaa agtggttcaa atgtaatatt aaaacttgga ttagcacaaa aaataactaa
    33121 gggaagaaaa gctacaataa ataaatatgt tgaagttaca cttccaaaaa gtttagaata
    33181 catagttgaa aatgaattat caaaaccgga tgaattacca ccagataatg gcaatggtgg
    33241 aaataatggt ggtggaagta attcaggcgg ctcgtctagt ggtggaagtt ctggaggagg
    33301 aagttcaagt aattctacat ctaatgtcac agtcaaaaaa ttaaaaggtg ctgatagatt
    33361 tgagacagct accaaaatat ctcaaagtgg ttggacaaaa tcagatacag ttgtaatagt
    33421 aaatggagaa gataaaagca tggtggatgg gcttacagct acaccacttg ctagtgtaaa
    33481 aaactcaccg attcttttat catcaaatga aaagcttcct caaaaaactg tagaagaatt
    33541 gaaaaggcta aatccatcaa aagtaattgt gataggtgga aacaactcaa tgccaaattc
    33601 agttgttgaa gctatcaaag ctgtaaattc aaaaatatca gtacagagaa taggtggaga
    33661 tacaagatat caaacttcta ttaatatagc aaaagaaata gataagacga ataatgtaag
    33721 caaattgtat ataggggcag gaaatggaga agcagattca ttatcaatag catcactggc
    33781 cggtaaagaa aaaactccaa tagtacttac acaaaaagat ggtgtagata atgaagctgt
    33841 acaatttatt aaatcaaata aggtgtcaaa tatatacttt attggtggaa tagaaaaaat
    33901 atctaacaag gctattgaac aagttggaaa aatagcaaac aaagatatat caaacaatag
    33961 ggtggcaggt caaactagac aagagacgaa tgccaaagta atagataaat tctactctca
    34021 atctaaacta gatggagttg tagttgcaaa tcaagataaa cttatagatg ctttagcagt
    34081 tggaccatta gcagctaaaa acaattcacc agttatactt gctacaaata cgttagataa
    34141 atcacaagaa tcatcattaa aaggtaaaaa ttcatcaaag ttgtttgaag taggtggagg
    34201 aatagcctca tctgtagtag ataagattaa gagtttaatt gaaaaataaa tattaagtaa
    34261 atcgaaaata agaatgtatt tagatataaa gttatatatt tagatgcatt cttattttat
    34321 tttcattatc ttaacaattt aataatattg aggttaaaat gtataataat ttgagctata
    34381 ttaagtttaa ttttaaataa agcagatatc ttttatatat ataaatataa attcaatttt
    34441 gaatatgttt aaaaagaagt taaaaataat tttttaaatt taataaaata aaacactaat
    34501 atatagacga gatatattca tatcatatat actctataat atatggaaaa taaagagaaa
    34561 ataaatagaa aataatcaca atataaatat aaaatataaa aatcatcagg gggatatgaa
    34621 aatgaacaaa aaaatattat cattaggtct agcagtatca ttaatcttag taaacttcaa
    34681 aagtgtaaat gcatcatcag tagtagaaaa aatatacggt aaagatagat atgaaacagc
    34741 agcaaagata gctgatagac agacttatga aacagtaatt ttagtaaata cagaaaaatc
    34801 acttgcagat ggattaagtg caagtggatt atcgggagct acaaaagctc caatactatt
    34861 tacacaacaa aataagatac cagcagacac aaatagatgt ctaaaaaata tcaaaaaagc
    34921 atatataata ggtacagaag atactataag taaatcagta gaaaaagaac tagattctaa
    34981 aaatatagaa gtcaaaagaa ttggtggaga agatagacta aaaacaagct atttaatagc
    35041 taaagaaata gcaactataa aaaaagtgga taaagtacta ttaactaacg catatagtgg
    35101 agaagcagac gcaatgagtg tatcatcagt agctactaga gatggagctc caatcatact
    35161 tacagatgga aagagtgtgc cttttgatgt aaaaaatatt caatcatatt gtataggttc
    35221 agaggagata atgagtaacc ctctagttaa aaatacaaac tcagtaagaa tagaaggaac
    35281 tgaccgattt gaaactaaca aaaatgtaat agactacttt tttaatagtg cagatggatt
    35341 ctatgtatca gatggatacc aattagtaga tgcaatagca gctgcaccac ttactaaaaa
    35401 ctctccaatg gtactagtaa atgatggaag cgataaaact gtattagaag gagctaagaa
    35461 tataacttct gtaggtgaaa taaatgagaa ggtaatacaa cagtgtataa atgcttcaaa
    35521 gtcaaatgga caaccaccaa caattacagt tggaagtaca gagatatata agggtgaaaa
    35581 gtttgacact ggcaagttaa acatagtggc taaagataac actgggaagg tattaccaat
    35641 agaagttgat gggtttatag atacaaatag agtaggtaca tacatattga cattaaaagc
    35701 tacagacgaa tggggaaaaa gtacaggaaa aagagtagaa ataaaagtgt tggatgataa
    35761 atcctatgat tacaacagcc cagaatttaa aaaaatggta tctactgaaa tgtataactt
    35821 aatcaattcc tatagaaaag aaaaaggcaa agagcctttg gtagtatcta gtaggctaga
    35881 aggtatggca aatgcatggt ctaagtatat gatggataaa aaagtatttg cacattatat
    35941 agatggaaaa aatgctccac aagtattttc tgagtttgga atgagaagtg aggaaaatat
    36001 agcatatatt tatatagatt ctaagaacgt tcaaacgaca caagatgcaa aaaacttggc
    36061 aaaggctata tttgaagtgt ggaagaagtc tccagagtac aatgcaaaca tgcttagtga
    36121 tgagttctat agtactggat ttgggcttta tatattatct gatggtcaag tgcatgctac
    36181 tcaggagttt ttaaatggca atgaaggtag tttgtaaaaa attccataaa tcttgttttt
    36241 ttgttaattt actgatatta taaaatgaaa atcacatcta aagtactttt tgtaatctgt
    36301 tttgttattg ctttacaggc tatggtattt taggtgtttt ttgttttagt agtttataga
    36361 ttttgaggga atcactactg aggatgtaat ttatgattag ctgaattata taaaaaaatt
    36421 agtaggagga gttcgatgaa ggtaaataag agagtattat caataggatt gacaatatca
    36481 ttaataatgg caggagcacc aaatatcaat gcactttcga gcatagaaaa gatacaaggg
    36541 aaagatagat atgagacagc tgccaaaatt gcacagaaac aaacatatga aaatgtagta
    36601 ttagtaaata cagataatac actagctgat ggattaagtg caagtggatt agcaggaaca
    36661 gttaaagcac ctatattatt atcacaaaga aacagtatac catcagacac agaaaaaatg
    36721 ttaaaagatg taaagaaggt ttatataata ggaactgaag attcaatagg aaaatcagtt
    36781 gaaaatgaat taaagcaaaa aggaatagaa gttaaaagaa taggtggtaa tgatagaatt
    36841 gaaacaagtt atcttatagc aaaagaaata gcttcaataa aacctataga taaggttttt
    36901 ataactaatg gttatacagg tgaagcagat gctatgagtg cgtcatcagt agcatcaaga
    36961 gatggatcac ctataatttt aactaatggt aaaaatgttc catttgagaa aaaagaaggt
    37021 gtgcaatgtt atgctcttgg ttcagaggag ataataagta atgatttagt taaaaaaact
    37081 aatgcagtta gattagctgg agaagataga tttgagacta ataaaaaagt tataaaacat
    37141 ttttatagtt cggcaaaaga attttatctt tctaaaggtt atcaattagt agatgcagtt
    37201 gctggttctt ctatagcaaa aaatgcacct attgtattag ttgacggaaa tagtgataag
    37261 tctgtactta gaagtgctga taagattaca gcactaggag gaatagatga aaagacacta
    37321 gaacaatgtt taagtgcatc atcactggat gcaagtgcac caacaataac tgttggaaat
    37381 ttaaatattt atcaaggtga taagtttgat ataagtaaac tgaatatcgt agcaaaggat
    37441 agcaatggta acgatttgac accagagctt ataggaaata ttgatactga taaggtgggt
    37501 aaatacaaag ttactataaa agctactgat attggtggaa agactacatc aataagtgta
    37561 gaagtaaatg tacttgaata taagactaat gatatgaata gtagtgagtt taaaagaatg
    37621 gtttctagtg aaatgtatag tttggtaaat tcatatagaa aagaaaaagg taaagagcca
    37681 ttacaagttt ctaaaaactt agaaggactt tctaattcct ggtctaagta catggcagat
    37741 aaaggtcagt tttcacatgt aataaatggt aagaaatctg ttgaagtatt tactggatat
    37801 ggcttgagaa gtgaagaaaa tatagctttt gtaccacttg ttacaaaaag tacttataca
    37861 acaaaggatg ctagagaagt agcaaatgta atatttacag tttggaaaaa gtcagataaa
    37921 tataatgaaa atatgttaaa tagtgatttt gtatatactg ggtttggatt atatatattg
    37981 cctaatggag aagtgtatgc tacacaagaa tttttaaata agtaatttaa ataagtaaaa
    38041 tcaaattttt taagttatta aatattggag tttaagggta taaaaactca tatgcttggg
    38101 aaaaataata atttcaaaaa aatgacttgc aaaaagaata aaaatggatt attatagaga
    38161 tgtgagaaat attaggaata tatggatgat tattctatgt acataatgaa gagatgtaat
    38221 tttaatataa tgttgggagg aatttaagaa atgaataaga agaatatagc aatagctatg
    38281 tcaggattaa cagtattagc ttctgcagca cctgtgtttg cagcagaaga tatgtcgaaa
    38341 gttgagactg gtgatcaagg atatacagta gtacagagca agtataagaa agcagttgaa
    38401 caattacaaa aagggttatt agatggaagt ataacagaga ttaaaatttt ctttgaggga
    38461 actttagcat ctactataaa agtaggagct gagcttagtg cagaagatgc aagtaaatta
    38521 ttgtttacac aagtagataa taaattagac aatttaggtg atggggatta tgtagatttc
    38581 ttaataagct ctccagcaga gggagataaa gtaactacaa gtaaacttgt tgcattaaaa
    38641 aatttaacag gtggaactag tgcaataaaa gtagctacaa gtagtattat tggtgaagtc
    38701 gaaaatgctg gtactccggg agcaaaaaat acagctccaa gtagtgctgc agttatgtct
    38761 atgtcagatg tatttgatac agcttttaca gattcaactg aaactgctgt gaaacttact
    38821 ataaaagatg ctatgaaaac taaaaagttt ggtttagttg atggaactac ttattcaaca
    38881 ggtcttcaat ttgcagatgg aaaaacagaa aaaattgtta aattaggaga tagtgatact
    38941 ataaatttag ccaaagaatt aataataaca cctgcaagtg caaatgatca agctgcgact
    39001 attgagtttg ctaaaccaac aacacaatct ggaagcccag taataactaa acttagaata
    39061 ttgaatgcaa aagaagagac aatagatatt gatgctagtt ctagtaaaac agcacaagat
    39121 ttagctaaaa aatatgtatt taataaaaca gatttaaata ctctttacag agtattaaat
    39181 ggggatgaag cagatactaa tagattagta gaagaagtta gtggaaaata tcaagtggtt
    39241 ctttatccag aaggaaaaag agttacaact aagagtgctg caaaggcttc aattgctgat
    39301 gaaaattcac cagttaaatt aactcttaag tcagataaga agaaagactt aaaagattat
    39361 gtggatgatt taagaacata taataatgga tattcaaatg ctatagaagt agcaggagaa
    39421 gatagaatag aaactgcaat agcattaagt caaaaatatt ataactctga tgatgaaaat
    39481 gctatattta gagattcagt tgataatgta gtattggttg gaggaaatgc aatagttgat
    39541 ggacttgtag cttctccttt agcttctgaa aagaaagctc ctttattatt aacttcaaaa
    39601 gataaattag attcaagcgt aaaagctgaa ataaagagag ttatgaatat aaagagtaca
    39661 acaggtataa atacttcaaa gaaagtttat ttagctggtg gagttaattc tatatctaaa
    39721 gaagtagaaa atgaattaaa agatatggga cttaaagtta caagattagc aggagatgat
    39781 agatatgaaa cttctctaaa aatagctgat gaagtaggtc ttgataatga taaagcattt
    39841 gtagttggag gaacaggatt agcagatgcc atgagtatag ctccagttgc atctcaatta
    39901 agaaatgcta atggtaaaat ggatttagct gatggtgatg ctacaccaat agtagttgta
    39961 gatggaaaag ctaaaactat aaatgatgat gtaaaagatt tcttagatga ttcacaagtt
    40021 gatataatag gtggagaaaa cagtgtatct aaagatgttg aaaatgcaat agatgatgct
    40081 acaggtaaat ctccagatag atatagtgga gatgatagac aagcaactaa tgcaaaagtt
    40141 ataaaagaat cttcttatta tcaagataac ttaaataatg ataaaaaagt agttaatttc
    40201 tttgtagcta aagatggttc tactaaagaa gatcaattag ttgatgcttt agcagcagct
    40261 ccagttgcag caaactttgg tgtaactctt aattctgatg gtaagccagt agataaagat
    40321 ggtaaagtat taactggttc tgataatgat aaaaataaat tagtatctcc agcacctata
    40381 gtattagcta ctgattcttt atcttcagat caaagtgtat ctataagtaa agttcttgat
    40441 aaagataatg gagaaaactt agttcaagtt ggtaaaggta tagctacttc agttataaat
    40501 aaattaaaag atttattaag tatgtaatat aaatataata atataaaaag gcttcttata
    40561 tgagaagtct ttttatatta tgttttcgaa tacaaaaaaa gagactaaat ttagtctctt
    40621 ttttatgtga gaaatactta aatatataaa gatgtaattt atttaagtat gattattata
    40681 ctatacaata aaataattgt ctactattct ataattttaa ggtataataa taattgtatg
    40741 ataaaagagg aggtcaaaaa atatgtcagt tttagatgca atcttagata aagcggatga
    40801 acaagaaatt aaaaaattaa atttaatagt agataaaata gaatctttag aaaaagatat
    40861 ggaaatcaaa gagaatgaac aattaaaaga aatgacaaat acttttagac ttagattaga
    40921 caaaggtgaa agtttggatg atatacttcc agaagcattt gctgttgtta gagaggtctc
    40981 aaaaagagtt ttaggaatgc gtcaatataa agttcagtta attggaggta tagtaattca
    41041 tcaaggaaag atagctgaga tgaagactgg tgaggggaaa actttagttg aggtagctcc
    41101 agtatatcta aatgctttaa caggaaaagg tgtacatgta attacagtaa atgattattt
    41161 ggcagaacgt gataaagaac ttatgcgtcc agtatatgaa tttttaggat tgactgtagg
    41221 tgtaatttta tctaaccaag acccaagtat aagaaaagaa caatataaat gtgatataac
    41281 ttatggaaca aatagtgaat ttggatttga ctatttaaga gataatatgg tgccagattt
    41341 gtctcataaa gtacaaaggg aactaaactt tgccatagta gatgagatag actcaatatt
    41401 aatagatgaa gctagaactc cacttattat tgcaggagat ggtgatgaag atttaaaact
    41461 ttatgagtta gcaaataact ttgtaaaaac tgttaaagaa gaagactttg agatggatag
    41521 aaaagataaa actatagcat taacagcaag tggtataagc aaagctgagt cattttttgg
    41581 tataacaaac cttactgata taaagaatat agaattatat catcatataa atcaagcttt
    41641 aagaggtcat aagcttatgg aaaaagatgt tgactatgtt atctcaaatg gagaagtaat
    41701 gatagttgac gaatttacag gaagagtaat ggatggtaga agatatacag atggacttca
    41761 ccaagctata gaagccaaag aaggtgttga gataaagaat gaatctaaaa ctatggctac
    41821 tgtgacttat caaaatttct tcagactata tgaaaaactt tctggtatga ctggtactgc
    41881 aaagacagaa gaaggggaat ttgagtcaat ctataaatta aatgttgtcc aaataccaac
    41941 taatagacca gttattagag ctgatttgca tgataaggta tttaaaacag aagaagaaaa
    42001 gtatagtgct gttgtagaag aaataataag gatacataag actagacagc caatactcgt
    42061 gggaacagtt tctgttgaaa aatctgagaa gttatctaaa atgcttaaga agcaaggtat
    42121 taagcatcaa gtcttaaatg ctaaacaaca tgataaagag gcagaggtaa tttctaaagc
    42181 tggtaaatta gatgctataa cgattgctac aaatatggca ggtagaggta cggatatttc
    42241 tctaggtgca ggagataaag aagaagaaga aaaagttaaa aatttaggtg gtctttatgt
    42301 tataggaaca gaaagacacg aatcaagaag aattgacaat cagcttagag ggcgttctgg
    42361 tcgtcaagga gacccaggta catcaagatt ttttgtaagt cttgaagatg atgtaataaa
    42421 gctttatggt ggaaaaacta tagagaaact tatgaagaga acaagttcaa aggaaaatac
    42481 ggctattgaa agtaaagcac ttacaagggc tatagaaaga gcacaaaaag gtgtagaagg
    42541 taagaatttt gaaataagaa aaaatgttct taaatatgat gatactatta atgagcaaag
    42601 aaaggttata tataatgaaa gaaataaagt gttaaatgat gaagatataa aagaagatat
    42661 tcaaaaaatg gttaaagaca tcatacaaga agcaggagaa acttatttaa ttggaagaaa
    42721 aagagattat tatggatatt ttaaacattt atatagtaca tttatgcctg cagatacatt
    42781 actaataccc ggtgtagata aaaaaagtgt ccaagagata attgatagca catatgaaat
    42841 ttcaaaaagg gtttatgact tgaaaaagat gatgattggt attgataaag ttgcggagtt
    42901 agaaaaaaca gtacttttaa aagtggttga tcaatactgg atagatcata tagatgctat
    42961 ggaacagtta agacagtata taggtcttaa atcttatgct caaaaagatc cgtttaaaga
    43021 atatgcttta gaaggatatg atatgtttga agctttaaat aaaaatataa gggaagcaac
    43081 agtacaatac ttatataaat ttaactaaaa aagttcatgt aatttttatt aaatgaaaaa
    43141 taaaatattt tgattcttta tattgtaatt acaattaaat aattaaggaa tacaaatgaa
    43201 aaagaagctg aaaatcagct tctttttctg tgtgagaaat acggaaaaaa gagatgcttg
    43261 aaatttcttt cttccattta atattatact ataaagaaga tgaaaagtct attagttata
    43321 aactggatta ttaaaaaaaa ttacaatttt gttacttttt tgtatacata aatattaaaa
    43381 aaataaaata taagaaaaag tttatatctt ttggttaatt attacaataa gtctcattta
    43441 ttgaaataat atcaaatata tattataatt ggtaaataag gaaaaaataa taaaaatttg
    43501 aattttttag ggggaaaata ccatgaataa aaaaaatctt tctgtaatta tggctgctgc
    43561 aatgataagt acatcagtag ctccagtttt tgctgcagaa actacacagg taaaaaaaga
    43621 aacaataact aagaaagaag ctacagaact agtttcgaaa gttagagatt taatgtctca
    43681 aaagtatact ggtggttctc aagttggaca accaatatat gaaataaaag ttggcgagac
    43741 tttatcaaaa ttaaaaataa taactaatat agatgaatta gagaaattag taaatgcttt
    43801 gggagaaaat aaagaactta ttgtaactat aacagataaa gggcatataa caaatagtgc
    43861 aaatgaagta gttgcagaag caactgaaaa atatgaaaat tcagcagacc tttccgctga
    43921 ggctaattct ataacagaaa aagctaaaac tgaaactaat ggaatttata aagttgcaga
    43981 tgtaaaagct tcatatgata gtgctaaaga taagttagtt ataactttaa gagataaaac
    44041 agacacagta acttctaaaa ctatagagat aggtattggt gatgaaaaaa ttgatttaac
    44101 agcaaatcca gttgattcaa cgggaacaaa cttagaccct tctacagaag gatttagagt
    44161 aaataaaatc gttaaactag gtgtagcagg agctaaaaat attgatgatg tccaattagc
    44221 tgaaataact ataaaaaata gtgacctaaa tacagtttca ccacaagatt tatatgatgg
    44281 atatagatta actgttaaag gtaatatggt agcaaatgga acatcaaagt caattagtga
    44341 tatttcatca aaagattcag aaacaggaaa gtataaattt actattaagt atactgatgc
    44401 atctggaaaa gcaatagagc ttactgtaga aagtactaat gaaaaagatt taaaagatgc
    44461 caaagctgca ttagaaggta attcaaaggt taaattgata gctggagatg atagatatgc
    44521 aactgcagtg gctatagcaa aacaaacaaa atatactgac aatatagtta tagttaattc
    44581 aaataaacta gttgatggat tagcagctac accacttgct caatctaaaa aagcacctat
    44641 attattagca tccgataatg aaataccaaa agtaacttta gattatataa aagatataat
    44701 taagaaaagc ccatcagcta aaatatatat agtaggtgga gaatcagcag tatcaaatac
    44761 agctaaaaag caattagaat cagtaactaa gaatgttgaa agactagctg gagatgatag
    44821 acatatgact tctgtagcag tagcaaaagc tatggggtct tttaaagatg catttgtagt
    44881 aggtgcgaaa ggggaggctg atgctatgag tatagctgcc aaagctgctg aacttaaggc
    44941 tcctataata gtaaatggct ggaatgatct ttcagcagac gctatcaaat tgatggatgg
    45001 aaaagagatt ggtatagttg gtggttctaa caatgtatct agtcaaattg aaaatcaact
    45061 tgctgatgtt gataaagata gaaaagttca aagagttgaa ggagaaacaa gacacgatac
    45121 taatgctaag gttatagaaa catattatgg aaaattagat aaactatata tagcaaaaga
    45181 tggatatgga aataatggta tgctagtaga tgcattggca gcaggacctc tagcagcagg
    45241 taaaggtcca atacttctag ctaaagctga tataacagac tcacaaagga atgcacttag
    45301 taaaaaatta aatcttggtg cagaagtaac tcaaataggt aatggagttg aattgacagt
    45361 aatacaaaag atagctaaaa tactaggttg gtaataactt atactgtgga gaagattcct
    45421 taattaatac aggaatcttt ttctataatt atgctattta ttgtaaatta taacatttta
    45481 taaagtagga ggatgtagta gtggtagatg caactttatt ttttacacca catcaagatg
    45541 atgaaacctt aagtatggga agtgctataa ttgaacatgt tgaaaaaagt gatacacatg
    45601 tcatattatg cacagatggt agtaaatcta taataagaaa agttttggat gatggagggt
    45661 catgttctta tcatattaaa gatgttcata aatactcttt atcagaaagt gaattttcaa
    45721 aagatagaga tgaagaattt aaggatagct gtgaagcaat gggtgtaaaa gaaagtaata
    45781 tacatataga agataataga gcacatgatg gtgagttaag taaagaaaag gcaagggaaa
    45841 taatacttaa gtacttagaa gaatatccag atgcaaaagt aaaaactgtt actccgttta
    45901 aagctagtgg aatacatgaa gaccataggg cattaggaga agctgcacta gagttatata
    45961 aagaaggcaa aataaaagat ttaagatttt atgtagaacc atacgactat aaggatttta
    46021 aaaaagttaa tccaaatgta gaggtatgga aggtattacc tagtcaagag gagaagttat
    46081 taagtgcaat gaatgcatat aaaaaatgga atcctgaaag tggacattat gctataggat
    46141 atcattcagt aaaatctcat tttgatgagc tagctataaa taaaatacag tatgtacatg
    46201 ctccataaaa tattatgaaa gaattaggag gtaagaatta atgaaaatat caaaaaagat
    46261 agtgtctttg ttaactatga catttttaac tgttacatta tatggaaata catctaatgc
    46321 atctacaaaa gatacattaa caggttctgg aagatgggaa acagcaataa aaataagtca
    46381 agcaggatgg aaaaagtctg aaaacgctgt gctagtaaat gataattcaa tagcagatgc
    46441 tttatcagct actccatttg ctaaagcaaa agatgcacca atattattaa ctcaaagtaa
    46501 taaattggat agtagaacaa aagcagaatt aaaaagactt ggtgtgaaaa atgtatattt
    46561 aataggtggt tcaattgcat taagttcaga gattgaaaag cagttaaatg cagaaaatat
    46621 aagttttgaa agaatatctg gaaatagtag atatgatact tctttaaaat tagctgaaaa
    46681 gctagatagg gaaaaatcta tatctaaaat agtagtagta aatggagaaa agggtcttgc
    46741 tgatgcagtg agtgttggag ctatagctgc tcaagaaaac atgccaataa tactttctga
    46801 ttcagagaat ggaactgaag tagctgataa ttttatagat agtaaagata tagaaaaatc
    46861 gtatgtaata ggtggtacat attctatttc taattctgta gaaagaagtt taccaaatgc
    46921 aacaagaata gcaggtagta gtagaagtga gacaaatgca aaaattatag aagaatttta
    46981 caaagatact gatataaaaa atatttatgt aacaaaggat ggtacaagga gtaagcatga
    47041 tttaatagat tctttagctg tgggtgtatt agcttctaaa aatggttctc caatactttt
    47101 agcaggaaat aagctagata gttctcaaaa agatgtgtta aacactaaaa ttatagataa
    47161 agttattcaa attggcggat tgggtaatga aaatgttgta gaagatgtaa tagatatgca
    47221 agaagaaact aagtatactg ttgaaactat tgatgaactt aatgttgcta taaaaaaatc
    47281 agatgcaaat gacatcataa gatttaagcc agaaaaagat aaaaatataa ctaattcttt
    47341 taaaatagaa acaaataaag ctataactat tgaatttgat ggtatatata aacaatcaat
    47401 aactatagat atgccaaatg gagatataaa aaactttggg gacatagata atgatctagt
    47461 aataaataat ataaaaaatg agactttagt taacgaagga agtatacaag ggatagatgt
    47521 ttatgatgag aatggatgta aaatagagaa tgaggattct ggagaaatat ggcttataac
    47581 gatacttaaa aattcaaaag atgtatatat tttgaatcgt ggagaaataa ctaaaatatc
    47641 taataattct tctagtgtaa caataaaaaa ttcaggtaat attaatacta taagtggaag
    47701 tgaagaacca tcaataagtg gtaaaaaacc tataactaat gatacagata aagatgaaga
    47761 taaaaaggca cgtggtttat atcctaaagt agaatcttgt atacctgctt taaaagatta
    47821 tgtaagaata actatatcaa caaaaccaga gagttcaaag tataaaattt attatagagt
    47881 agttgatgaa aaaccatctg cgaaatatgt tggagaaaaa attagtacta aaggttggag
    47941 tatggttaca atatcaaatc aatcttttat tgaaagagcc aaagatggat catatataga
    48001 agcagtagaa atagatacct caaataatga agtttcacga tggggaaaat ctagcattac
    48061 agatgatgga atttagacat taaacttatt cattttgcag attactattt agtaatctgc
    48121 tatttatttt ttaaaaatta tcatcttgct aaacaagtaa tttaaaacta taacaactat
    48181 attagtaaat atttttacaa taacatcatt tacaaaaagc aaatcaatca ttacatacat
    48241 aattaacatt tcaacgacac cagaaagtag cctaaaacta acaaaagaca aaaattcttt
    48301 aaatacgaac cttatttcaa ttcttttact ttcaaataca aaaaacttat tagtaacata
    48361 agcaaataaa acagcaagta tccatgccaa agcatttgca accataaaat taaataaaat
    48421 aactctagta aaaaataaat acgaaactat atttacaaga gtagtaaatg ctccaaaaaa
    48481 taaatataat attgtctctc tatgcttttt taaaatcaaa tataatcctc ctaatctaat
    48541 ttaatataaa tatacttaaa gatactaaca aacattagta tagcacatct attaataaat
    48601 caatatatct taaaatatta taaaaataaa actataatat tctataatta atatgtactc
    48661 ataatccata ttttatcaaa ataaaatatg accttaattt agaaatctga tataataaaa
    48721 attaaataca tataaggggg taaacatgag aaagtacaaa tcaaaaaaat tgtcaaagct
    48781 actggcattg ttgacagttt gctttttaat agtgtcaaca atacctgtct cagcagaaaa
    48841 ccataaaact ctagatggag tagaaactgc agagtattct gaaagttatc ttcaatacct
    48901 agaagatgtc aaaaatggag acacagcaaa atataatgga gtaatacctt ttccacatga
    48961 aatggaaggt acaacacttc gaaataaggg cagaagtagt cttccatcag catataaatc
    49021 aagtgtagca tacaacccaa tggatcttgg tcttactaca ccagcaaaaa atcaaggaag
    49081 tcttaataca tgctggtctt tttcaggtat gtcaacttta gaagcatatc ttaaattaaa
    49141 gggatatgga acgtatgact tatcagaaga acatttaaga tggtgggcaa ctggtggaaa
    49201 atatggatgg aacttagatg atatgtcagg tagttcaaat gtaacagcca taggatatct
    49261 gacagcatgg gcaggtccta agttagaaaa agatatacca tataatctta aatctgaggc
    49321 acaaggtgca actaaacctt caaatatgga tactgcacct actcaattta atgtaacaga
    49381 tgttgttcgt cttaataaag ataaggaaac tgtaaaaaat gctataatgc aatatggttc
    49441 agtgacatca ggttatgcac attattcgac atattttaat aaagatgaaa cagcatataa
    49501 ctgtacaaat aagagggctc cattaaatca cgctgtagcg atagtaggat gggatgataa
    49561 ttattcaaaa gataactttg catctgatgt aaaaccagaa tcaaatggag catggttagt
    49621 aaaaagcagt tggggagaat ttaattctat gaaaggattc ttctggattt cttatgaaga
    49681 taaaactcta ctaacagata cagataacta tgcaatgaaa tcagtatcga aaccagatag
    49741 tgataaaaaa atgtaccaac ttgaatatgc tggtcttagt aagataatgt caaataaagt
    49801 aacagcagca aatgtatttg attttagcag agattctgaa aaacttgact ctgttatgtt
    49861 tgaaacagac tctgtaggag caaaatatga agtatattat gcaccagtag taaatggagt
    49921 tcctcaaaac aactcaatga caaaacttgc aagtggaaca gtatcatatt ctggatacat
    49981 aaatgtacct actaattctt acagcttacc aaaaggtaaa ggagcaatag tagtagttat
    50041 agacaacaca gcaaatccta atagagaaaa atcaacttta gcatatgaaa ctgatataga
    50101 tggatactat ctatatgagg ctaaagcaaa cttaggtgaa agctacatac ttcaaaacaa
    50161 taagtttgaa gatataaata catatagtga attttctcct tgtaactttg ttataaaagc
    50221 tataacaaaa acatcttctg gacaagctac ttcaggagaa tctttaactg gagcagatag
    50281 atatgaaacg gcagttaaag ttagtcaaaa aggatggact tcttcacaaa atgcagtatt
    50341 agtaaatgga gacgcaatag tggatgcttt aacagctaca ccatttacag cagcaatcga
    50401 ctctccaatt cttttaacag gaaaagataa cttagattca aaaactaagg cagagttaca
    50461 aagattagga actaaaaaag tttatctaat aggtggagaa aattctttaa gcaagaatgt
    50521 acaaactcaa cttagtaata tgggtatatc agtagaaaga atttcaggta gtgatagata
    50581 caagactagt atatctctag ctcaaaagtt aaatagtata aaatctgttt cacaagttgc
    50641 agtggcaaat ggtgtaaatg gacttgcaga tgcaataagt attggtgcag cagctgctga
    50701 taacaatatg ccaataatac ttactaatga aaagagtgag ttgcaaggtg ctgatgagtt
    50761 tttaaattca tcaaaaataa ctaagtctta tataattggt ggtacagcta ctttatcatc
    50821 aaatttagaa agtaagcttt caaatccaac aagacttgca ggaagtaata gaaatgaaac
    50881 taatgctaag ataatagata aattctaccc tagctcagat ttgaaatatg cttttgttgt
    50941 taaagatggt tcaaagagtc aaggagactt gatagatgga ctagcagtag gagcattagg
    51001 tgctaaaact gattcaccag tagttctagt tggaaataag ttagatgaaa gtcaaaaaaa
    51061 tgtacttaag tctaagaaaa tagaaactcc tattagagtt ggtggaaatg gaaatgaaag
    51121 tgcttttaat gaactaaata ctcttttagg aaaatagtga atggaaagat agtaaggata
    51181 tacattttat tattaaaaaa tattcaatag aagtttataa atataaaata acaaaaaggg
    51241 gtgtctcaaa atgaactttt tagttcatga ggcactcttt tttgttgttt tatattttta
    51301 tcatttaaat aatgaaaaat aggcttgtct atatttttag atagttttct tattattgat
    51361 gaaaaatgta ataattttaa actgtaaaat agtgtaaagt tattttataa tataaatata
    51421 gtaagatttt aaacaaaata agggggaata ataatgaaag caccaaaaac tattttaaca
    51481 atactgacaa tagcgcttac tttaagtagc atttctataa taccatcata tgcacttaca
    51541 gaggaaaaat taataggtaa tggtagatat gaaactgctg taaagataag tcaaaaggca
    51601 tacagttcta gttctaatgt agtgttagtt aatgacaatt cattagctga tgcactttca
    51661 gctacaccat ttgcaaaggc taaaggagca ccaatacttt tgacagaaag tgataagcta
    51721 gatgatagga ctgaaaaaga gataaaacgt ctaggagcta aagatattta tttgatagga
    51781 ggtactgctg tacttaataa agatatagag aacaagttaa aaggtaatgg acttaatgta
    51841 gaaagaatta atggtaagga tagatatgaa acttcactga ttttggctaa taagcttaag
    51901 gatataaaag atattaagga agttgctgta gtaaatggtg aaaaaggatt aagtgatgct
    51961 gttagtgttg gagcaccagc agctcaaaat aagatgccta taattttgtc tagtcctaag
    52021 gacggagtag aagcatttga taaatttata agagatgaga aagttataaa agcatacgta
    52081 attggaggaa caaattctgt ttcaagagct gtagaaaaga gccttcctaa tgcagaaaga
    52141 gtgagtggaa aagatagaaa tgagactaat gccaaagtta tagaaaagtt ttatactgat
    52201 acaaatttaa gtaatttata tgtaactaag gatggtagta aaaatgagaa tcaactaata
    52261 gactcgttag ctgttggagt attggctgca aaaaatgagt ctcctgttgt tttggttggt
    52321 aataaattaa acacgaaaca aagggatata cttagtacta aaaaattaaa tactataaca
    52381 caggtaggtg gaaatggaaa tgaagaagct tttgatgaaa ttaagagttt acaagaaaaa
    52441 actgtgtttg aagcaaaaac tgttgaggaa ttaactgata tgataaatat agcaagtcct
    52501 aatgatatta taaactttaa accaaaagag aatactgtaa atgaagcttt tagaatggta
    52561 acaaataaac caataactgt gaatataaag ggtgattgtt caaagactct tacagtagat
    52621 atgcctaatg gtgaagtgaa taactatgct actttggtaa atgttatagt tagaaatatt
    52681 ggagaaggtg gatttaataa ccatgataca atcactatat tgtcagttcg tgacaaaaat
    52741 ggtagagtta tagaaaatac tagaaattca gatatagata cgttgatgat attagcttct
    52801 gctaatgata caaaattgat taatgatgga tatataggaa agcttataga taattcatct
    52861 aatagtgata taactaataa tggtactata gataaaaaag ttaatcaagt tgagaattta
    52921 gaggctaaag tagattcaat tgaaaaagct atagattcta taagtcaaaa agtcaataaa
    52981 atacaagata tactagataa gattggattt ctaaagaaat ttcttagtta agaatatgta
    53041 tatttaagtg aagtgtgtgt tgtaattgtt ctaaagttat atagttaaac aggtttatat
    53101 acaaacagac ttatagataa atatgtagtt tagtatatat ttgaataagc tttggggagg
    53161 taacatgggg attggaattg aatgtaacaa aaaaataaat aaaagtattg acaaaactag
    53221 aataaagaaa aataatct
//
LOCUS       DAEQJM010000023        51922 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.023, whole genome shotgun sequence.
ACCESSION   DAEQJM010000023 DAEQJM010000000
VERSION     DAEQJM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51922
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.023"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            477..4025
                     /locus_tag="KRQ43_001681"
     CDS             477..4025
                     /locus_tag="KRQ43_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH2742039.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINNEMVIALMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTISCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKIIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDNFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADMALY
                     SAKGKGKNCYTLYDKKIDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESASNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMRNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEVTSIEAEENT"
     gene            4210..6144
                     /locus_tag="KRQ43_001682"
     CDS             4210..6144
                     /locus_tag="KRQ43_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBH2742040.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLENAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            6250..7245
                     /locus_tag="KRQ43_001683"
     CDS             6250..7245
                     /locus_tag="KRQ43_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2742041.1"
                     /translation="MKKYISIILLVVVTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSNIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7217..8002
                     /locus_tag="KRQ43_001684"
     CDS             7217..8002
                     /locus_tag="KRQ43_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH2742042.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7990..8688
                     /locus_tag="KRQ43_001685"
     CDS             7990..8688
                     /locus_tag="KRQ43_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742043.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8811..9284
                     /gene="ybaK"
                     /locus_tag="KRQ43_001686"
     CDS             8811..9284
                     /gene="ybaK"
                     /locus_tag="KRQ43_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBH2742044.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9481..10320
                     /locus_tag="KRQ43_001687"
     CDS             9481..10320
                     /locus_tag="KRQ43_001687"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HBH2742045.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10333..10881
                     /locus_tag="KRQ43_001688"
     CDS             10333..10881
                     /locus_tag="KRQ43_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HBH2742046.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10947..12128
                     /locus_tag="KRQ43_001689"
     CDS             10947..12128
                     /locus_tag="KRQ43_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBH2742047.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYIYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12301..12564
                     /locus_tag="KRQ43_001690"
     CDS             12301..12564
                     /locus_tag="KRQ43_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH2742048.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            13090..13773
                     /locus_tag="KRQ43_001691"
     CDS             13090..13773
                     /locus_tag="KRQ43_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742049.1"
                     /translation="MSSILLVEDDLSLIYGLEFSIQKSGFSIDIARTVKEAMQMYEEK
                     NYDLLLLDVSLPDGNGFQICEKVREVSNIPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNVASNVNELSSNNITIKLLENRVFKGEFEVELTTAEYKLLC
                     LFMKNKNIVLTRKNILDKLWDGNGSFIDDNTLSVYVRRLRNKIEDNPENPKFLLTVRR
                     MGYKWNVIK"
     gene            13784..15025
                     /locus_tag="KRQ43_001692"
     CDS             13784..15025
                     /locus_tag="KRQ43_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2742050.1"
                     /translation="MKIFSNKDIKIFFLILISILVMFIIVGQIVVISITNNYKKTLIE
                     HDYNIAGYLYSIGVDKSKIPSAFVAHEDKYILKGKEILDTAGYGFDIDVSFTPSVKLF
                     QSKYIKTMSIYLLVFFTMIIFILYMYFFRQQSKIEEASYKIDLFMNGNINERLNTYEE
                     GSLSKLFSSIDVMSTSLNTHILKEKQSREFLKNTISDISHQLKTPLTALIMYNQILQE
                     ESHNSDVVEAFVQKSQSELERIETLIKNLLKITKIDSKTIVLNKNNVNLKNLIVKILY
                     SFETRAEKEGKVISINGSENTLLFCDYEWMSEALSNLIKNALDNTKENDKITIEWFET
                     TITTIVSVKDTGNGIHVEDIHHIFKRFYRSKFSKDNQGLGLGLPLVKSIVEQHNGTIS
                     VESKLSQGSTFTISFLKLTNM"
     gene            15097..15780
                     /locus_tag="KRQ43_001693"
     CDS             15097..15780
                     /locus_tag="KRQ43_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742051.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGRIFIDGKEICSMKEEKQTIFRRRNIGFIFQAYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKNHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSNDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGV
                     LTDLGVNRE"
     gene            15777..18107
                     /locus_tag="KRQ43_001694"
     CDS             15777..18107
                     /locus_tag="KRQ43_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH2742052.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIIIAVCLVTAIFGLADMAI
                     QCQKIQFIKDDGNWHIVIRNIDEKFISEINSRVDIAHHGRGQVVDSGEFKSKEILIQG
                     LDEEVAKQFNLEIIRGRYPIGENETLIDEDAVKSFNLKIGDFIKIKLADGRNKNYKIV
                     GEYSSISSLRATDKHGLILSILGTQAIKKSETYDYYYITFKEKVNIRKATSDIKNTFN
                     LSDKQIGKNERLLSIIGQGDSDFSKPLYLTAGLLFVLVLVASIIMIYNSFNMSVIERV
                     KFFGLLRCLGSSKHQVKKFVVLESLILSIKAIPIGLVLGSLVTIISSIFLKYVNELFS
                     SMPILKVSFIGIAFGIIVGFLTVILSAIIPAKKASRVSPLSAVRGNLMSKEILNNGKT
                     SKVANTGSFKIETSMGLNHAFSRKKSFVLMTSSFAISIILFLGFSVLIDLMYQGLKPM
                     KPEAPHISIVDPNFKSVLTKEDINEISNIKGVKKVYSRMMTDIEATYNGKKTKSQLIS
                     YEKYQFNWAKKYLLKGEVNENKLQSENLALVEEGHGFDIGDKIYIKNRNAEKELEVGG
                     ILSSIPFEAKDKYIGNIITSENTFTNITGIKGYIIMDIQVDKDTPGDLIENIRRVVDD
                     NLEVRDKRQSNLEVKNSFYTMATFVYGFVFIIAIISMFNIINSMNISVTSRKNYYGVM
                     RAVGISNRQLRRMVIVEAGSYAMSGCLLGSILGLMLHRYMFISLVSSMFHLEWQVPFN
                     LLLITVLTMIIITLLSVRKPVKKICELDIIDSINAQ"
     gene            complement(18288..19130)
                     /locus_tag="KRQ43_001695"
     CDS             complement(18288..19130)
                     /locus_tag="KRQ43_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH2742053.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKAGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            19425..20159
                     /locus_tag="KRQ43_001696"
     CDS             19425..20159
                     /locus_tag="KRQ43_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2742054.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            20169..21302
                     /gene="nagA"
                     /locus_tag="KRQ43_001697"
     CDS             20169..21302
                     /gene="nagA"
                     /locus_tag="KRQ43_001697"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH2742055.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNITHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            21401..22150
                     /gene="nagB"
                     /locus_tag="KRQ43_001698"
     CDS             21401..22150
                     /gene="nagB"
                     /locus_tag="KRQ43_001698"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBH2742056.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKLENTHLP
                     NGMADDIEKECLNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            22325..22597
                     /locus_tag="KRQ43_001699"
     CDS             22325..22597
                     /locus_tag="KRQ43_001699"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742057.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPIGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            23257..23961
                     /locus_tag="KRQ43_001700"
     CDS             23257..23961
                     /locus_tag="KRQ43_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742058.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILDTNI
                     LIETVWGFGFRLKEKS"
     gene            23963..25450
                     /locus_tag="KRQ43_001701"
     CDS             23963..25450
                     /locus_tag="KRQ43_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2742059.1"
                     /translation="MNNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVFSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            25655..27268
                     /locus_tag="KRQ43_001702"
     CDS             25655..27268
                     /locus_tag="KRQ43_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH2742060.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYEILEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNIHSQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQASFGNKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDSSVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(27958..28788)
                     /locus_tag="KRQ43_001703"
     CDS             complement(27958..28788)
                     /locus_tag="KRQ43_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2742061.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPITYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKI
                     "
     gene            28861..30588
                     /locus_tag="KRQ43_001704"
     CDS             28861..30588
                     /locus_tag="KRQ43_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742062.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLIMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFVKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNREHFEKKRF
                     DRTAIDYSETAISINKVFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALI
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGRKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDVKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEIKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            30625..32487
                     /locus_tag="KRQ43_001705"
     CDS             30625..32487
                     /locus_tag="KRQ43_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742063.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKVKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRRAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFSSEYDEEVV"
     gene            32820..33509
                     /locus_tag="KRQ43_001706"
     CDS             32820..33509
                     /locus_tag="KRQ43_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBH2742064.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNNCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSIDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            33614..34300
                     /locus_tag="KRQ43_001707"
     CDS             33614..34300
                     /locus_tag="KRQ43_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBH2742065.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKYGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            34317..36224
                     /locus_tag="KRQ43_001708"
     CDS             34317..36224
                     /locus_tag="KRQ43_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HBH2742066.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLTSVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETHKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDKKEVNAELTSSVVKT
                     NTDNETENKTTNDSESKNNTDKDKSGNDNNQKLEGPRGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            36677..37366
                     /locus_tag="KRQ43_001709"
     CDS             36677..37366
                     /locus_tag="KRQ43_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742067.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            37802..38341
                     /locus_tag="KRQ43_001710"
     CDS             37802..38341
                     /locus_tag="KRQ43_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2742068.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            38360..39403
                     /locus_tag="KRQ43_001711"
     CDS             38360..39403
                     /locus_tag="KRQ43_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742069.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            39405..40241
                     /locus_tag="KRQ43_001712"
     CDS             39405..40241
                     /locus_tag="KRQ43_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742070.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            40346..41020
                     /locus_tag="KRQ43_001713"
     CDS             40346..41020
                     /locus_tag="KRQ43_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742071.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            41020..42072
                     /locus_tag="KRQ43_001714"
     CDS             41020..42072
                     /locus_tag="KRQ43_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH2742072.1"
                     /translation="MIKFKKTISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            42516..43364
                     /locus_tag="KRQ43_001715"
     CDS             42516..43364
                     /locus_tag="KRQ43_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH2742073.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            43354..45018
                     /locus_tag="KRQ43_001716"
     CDS             43354..45018
                     /locus_tag="KRQ43_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH2742074.1"
                     /translation="MMFKIFNKSLLKLVIVLSIVLTISNFSLFSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINENYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKVTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKYISNISKILIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            45067..46323
                     /locus_tag="KRQ43_001717"
     CDS             45067..46323
                     /locus_tag="KRQ43_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH2742075.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYKVSKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIEGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTTVIISDILCVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            46346..48427
                     /locus_tag="KRQ43_001718"
     CDS             46346..48427
                     /locus_tag="KRQ43_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBH2742076.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASSFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGTNINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKPKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            48464..49549
                     /locus_tag="KRQ43_001719"
     CDS             48464..49549
                     /locus_tag="KRQ43_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH2742077.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDGSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWVENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDSSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            49603..50727
                     /gene="wecB"
                     /locus_tag="KRQ43_001720"
     CDS             49603..50727
                     /gene="wecB"
                     /locus_tag="KRQ43_001720"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBH2742078.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKALVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDSYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            50805..51779
                     /locus_tag="KRQ43_001721"
     CDS             50805..51779
                     /locus_tag="KRQ43_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH2742079.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSVTIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDIIRSYNLQLIDNKVETK"
BASE COUNT        20699 a         5244 c         8953 g        17026 t
ORIGIN      
        1 gtaaaaggat attataatat tttactagaa ttattatctg gtaacttaag ttttgagtat
       61 taatctaaaa tatatgtttt tatagggttt aaattttatg tatacaaaat taatttgcta
      121 actgaatcat ataaaaaaaa caaaatattt tttagaggga atgattagat actattttct
      181 ttgttatgaa attaattgaa gagtaattaa ttagaaaagg aataaataat aatgaatata
      241 ttacattatt actttttgat aaatcaaaaa taaagttata gtttttaata ttaattaaga
      301 atgatgaaat atgaataaag attttacaaa taaatcttaa gctatcttat ttaattctaa
      361 tgcaggaaga aggtaaatgt atattgaaaa aatcatagaa atagaagtaa acaacttaaa
      421 caaatacaaa ggtttgcaaa agaagtaata taattatata caatgaggat gtgagtatga
      481 tgaacagact aaagccaaga attttaggta ttagtatctt gtttattatt ataattattt
      541 taacatgtgg agctgttttc aagtttaaat ttaaattaga taataaatta aaagaaacca
      601 cacatacata tttgtctgag tttacagaac acaatataat taatctcaag acaagactta
      661 gtggtcaatt tgacatgctt gaatctattg ctaacttcat aggaaacttg aataatataa
      721 ataatgaaat ggtgattgct ttaatggatt ctgatgtaaa gcgaagttct ttaattagaa
      781 tgactatctc tacattagat ggggaatgtt attctaatga tggaatcacc cataatgttc
      841 aagatagaga ttattttaaa aaagctaaaa atggagaaaa gaatatttca gagcctttaa
      901 aatctattgt taataataaa gaaataatag ttttatctac cccagtttat aaaagtggga
      961 aaatagttgg tgttttaagt ggaatttatg attcaaaaaa gttaaatgag ttattaggat
     1021 tatctgcatt tgatgaaaaa gcagatgttt ttgttgcaaa gaaaaatgga gatatagttg
     1081 ctcaaaaaac aaataaaaat agaaagacga tatcatgtat atttcagctt tttgacaaag
     1141 ataattgtga tgaagatgat tgtctaaaaa ctataaaaga aaatatgaaa aatgataagt
     1201 ctggatattt taattataac ttagataatg aaaaatttat gttaaactat cagccacttg
     1261 gagttaatga ttggtatgtt ttttctgttg tgccaaataa aatagtgtct attcagtcag
     1321 agaatatatc ttatgatgta tatatttttg cattagaaat actactagtt atattgattt
     1381 ttataatata tatagcatgt attataaata ataacaccaa aattattata aatgaaaaag
     1441 aaaaatttaa agtactcact gataatatat taggaggggt taaaacctgt ttaaaagatg
     1501 aatatatgac tatgacatat gtaagtcagg ggtttttaga gcttacaggt tactcttgtg
     1561 aagatttaaa taaaatattt aaaaatagat ttaaagacat gatttataaa gatgatttag
     1621 acaagtttaa ttgtattatt ctaaatcaat tagaaaaaca agataaaatt gaagttgaat
     1681 atagaattgt aagaaaagat ggaagtataa tttggatttt ggagagaagt aagtctataa
     1741 atgataataa aggaagtgag tgtattcagg gagttttaac tgatataaca gaacttaaga
     1801 aaatacaaga agagttagat tcaaaaagat ttgaaataca ggctatcaat gatagtattg
     1861 ttggtggaat agtgataact gagataaatg atgattttga tagtatatat ttaaatgaag
     1921 gttatttaaa tatgattgga tatacacgca aacaactgga agatgagcta aataataaat
     1981 taatcaaact tatttttaaa gatgatagaa cagaattaat taatagtata aacaaacaac
     2041 tcaaattaag tgatacattt gcatctgaac aaagagttga aaaaagggat ggtactatta
     2101 tatggatttt attaaaagga agaaagataa tttatgataa tggaaaatct gtactttgtt
     2161 gtgttattgt agatatcact tctgctaaat tattagagca agaacttaaa aagagtgaag
     2221 aacgtcatga aatcattcta aagcagacgc aaaatatcat aatagaatgg gatatagaaa
     2281 aagataaaat gaatatatca cctaattggt ataataagtt taaatatgac cctataactg
     2341 aaaacgcaac aaaaaatata attaaatcag tagatatata tcatgatgat atggataagt
     2401 ttatttcatt aattaaactt acttcacaag gtagtgagta tgaagagtgt gaaattagac
     2461 ttagaactag agatactatt tacgcttggt ttagtataaa ggcaacaact ttatttgata
     2521 ataatggtaa accttataaa gtagtaggaa gtttgactga tattgatgaa tcaaaacgag
     2581 aagctgaaaa gttgaaagaa agggcagaaa aagaccctct tacagatttg tataataaaa
     2641 aagcatcaca atcacttata gaagagtaca taacattgga taaaaaaaga aaaggtgctt
     2701 taatgattat tgatattgat aactttaaag gaataaatga taatttagga catttatatg
     2761 gggatgctgt attaagtgaa attgcaaatg acctaataaa tctatttaga gcaaccgata
     2821 tagtaggcag aattggtgga gatgagttta ttgtatttat aaaagatatt tctgaaacaa
     2881 gagatattat aaataaagca gaagaattgg taaaaacatt tgaaaggtct tttttaggta
     2941 aaggacgaaa ttataaaata tcattaagtg taggaattgc taagtttcca caagatggta
     3001 tggactatat gacactattt agaaatgcgg atatggctct ttactcagcc aaagggaagg
     3061 gtaagaattg ttatacattg tatgataaaa aaattgataa agtccaatat ataactaata
     3121 caagaaatgc aggagatagt gataatgtag agatgtcttt taaagaacat atcacaaatt
     3181 atatatttga tatactatat gaatcaagtg atatagaagt ggcagtaaat ttaattctaa
     3241 gtattgtagg taaacacttt aatgtgagtc gcatgtatat atttgaaaat tcagatgata
     3301 atcgagtatg taaaaataca tttgaatggt gtaacgaagg tgtaacctcg gaaattaata
     3361 atcttaaaaa tatttgttac aaggatttag gcaactatct tttaaatttt aatgcagatg
     3421 ggttatttta ttgtaatgat attgaaaatt taggtagtga tgtgaaaaaa gtacttaagc
     3481 cacaaggcat acgttcaata ttacaatgta aaattttaga gggcaatgaa tttagagggt
     3541 tcataggatt tgatgaatgt tcatataatc gtatgtggac taatgatgaa gtgaacactt
     3601 tgacatttat atctaaaacg ctcagtatgt ttttattaaa aatgcgtatt cagagtaagc
     3661 tagaagagtc tttaacaatt caaaaatctg tgatggataa tatggatata tgggcatatg
     3721 ttgttgacag gaatacctat gaattattat ttatcaataa aaaaatgctt gagtcagcat
     3781 caaacactca tgtaggtgat ttatgttata aagcgatatg gaataatcaa gataaacctt
     3841 gtaaaaaatg ccctatgata tatttaaaag atggtgatga tacttataaa tcatttatgc
     3901 gcaataaaaa gtttgaggta caggcaaata taactacaac tactttgaaa tggtttgatg
     3961 ggaaagatgc atgtttaata tttggaagtg aagtaactag tattgaagct gaagaaaata
     4021 cttaaaatac tgtgttatat atatacttaa aatcgcaatt tgaatttatt agacttaaaa
     4081 tgtctatata aatcatttaa gttgtggttt taagtatttt ttatgatata attaagcgtt
     4141 aagaacaaaa ttaaaagata cttttgtata aaaaaatatt tgttaaatat atattgagca
     4201 ggtgataata tggaaaataa gtttttacca ataagcaaac aagatatgat agatagagga
     4261 tgggaagaat tagattttgt tctagttaca ggagatgctt atgtggacca tcatagtttt
     4321 ggaacagcaa taatatctag agttttagaa aatgctgggt ataaagttgg aataatagct
     4381 caaccagact ggagaactac agatgatttt atgaagctag gaaaaccgag acttgcattt
     4441 ctagttaatg caggaaatat ggattcaatg gtcaatcatt attctgtaag taaaaagcat
     4501 agagaaaagg atatgtattc tccaggtggg aaaatgggtt atagaccaga tagagctact
     4561 atagtatatt gcaataaaat aagagaagca tacagtgatg ttgcaatagt aataggtgga
     4621 attgaagcga gtttaagaag atttgcacac tatgattatt ggagtgataa ggttagaaag
     4681 tctatgttaa tagatagtgg agcagattta ttagtttatg gtatgagtga aaagcagatt
     4741 gtagaagtag ccaatgcact taatgatgga tatgacccaa aatatattag acatattgat
     4801 gggacatgct atatttcaga tacattggaa gaaatatatg ataaatatat attaattcca
     4861 tcatataaag aaatttgtga agataaaatg aagtatgtag aagcttttaa aattcaatat
     4921 gatgagcaag acccatttag aggtaatata attgttcaac ctcatggaag taagtatctg
     4981 gttcaaaata agccagaaaa accacttagt agagaagaac tagatgaagt atatggatta
     5041 ccatatcaga agacatacca tcctgtgtat gaaaaatttg gaggaatacc agctatagaa
     5101 gaagtaaaat ttagtatagt aagttcaaga ggctgttttg gtagttgttc attttgtgca
     5161 ataacatttc atcaaggtag agcagtgcaa agtagaagtg aaaaatcaat tattgatgaa
     5221 gcaataggaa taacaaattt agatgatttt aaagggtata tacatgatgt tggaggtcca
     5281 acagctaatt ttagaagacc agcatgtaaa aaacaaatta ctaaaggtgc ttgtaaaaat
     5341 agacaatgct tatctccatc accatgtaaa aatttagatg cagaccacag tgaatactta
     5401 catttactta gagctgtaag aaaattacct aaaataaaaa aggtgtttgt gcgttctgga
     5461 attagatacg attatgtaat ggcagataag aacaataaat ttcttagaga gttgatagag
     5521 catcatgtaa gtggtcagtt aaaggtagcc ccagaacata tatcagaaga agttttaaag
     5581 tatatgcaaa aaccagcagg aaaaacttat gataaattta gacagaagtt ttttgctata
     5641 aatgaagaat taggtaaaaa gcaatatttg ataccctatt taatgtctag tcaccctggt
     5701 tctaccttaa atagcgctat agagttagca gagtatttaa gagatactca ctaccaacca
     5761 gagcaggttc aggattttta tccaactcca gggactctat ctacaaccat gttttataca
     5821 ggtattgacc cgcttacaat gaagccagtt tatgttccta aatcaaaacg tgacaaggca
     5881 atgcaaaggg ctttattaca atatagagca cctagaaatt atgatttggt atactctgcg
     5941 ttagttgaag caggaagaga agacttaatt ggttttggac atagatgtct tataaagcca
     6001 aaaaatgaaa agccttattt taatagaaat aattctaaaa aaaatgtatc taaaggaaca
     6061 aataaaaaca aaaaaactaa tacaaataac agaagtaata aaaatcaaca aaaaagttca
     6121 actaaaaaaa agaaaaaaca ttaaagtata aataaaaata cttaaaaaag aaggattatt
     6181 cgataaatta acagaaatta gtataaataa atataattat tttaatgacg ttacctttgg
     6241 gaggaagaga tgaaaaagta tatttctata atattattag tggtggtgac tatggttgtt
     6301 ttggtaggat gttcaccagg aaaagataac cctaaaaata aggagctatc agttgtcaaa
     6361 caagtaaaag tagctgttcc agatggacta ccagcagtgg caatagctaa acttgcaaat
     6421 gaaaatccag agattaaaga aggatatgaa acagtgtata gcattgaaaa gacacctgag
     6481 gcgatttcca ctagagtgat gaaaaaagat gcagatatag ctatagttcc ttcaaacatg
     6541 gctgcaatag cgtataataa aacttcatca tataatattg ttggaactgt aggaatgggt
     6601 tcactttatt tggtgtcaac agaaaatata aaagattatt ctgatttagt tggtaaagaa
     6661 gttggatgta ctggaaaagg acttactcca gacataacta taaaaagtct tttgttacaa
     6721 aaggatataa attattcaaa tataaaattt aattatgtaa attcagcaag tgaactggta
     6781 ccattattgg ctactggtaa agttaagaca ggtattgttc cagaacctgc acttagtgct
     6841 ttgatgtcta aaaatccaga cataaaaatt ataaaaagtt taaatgactc atggaaggaa
     6901 gtaagtggtt caaaagacgg ttatcctcaa tctactttaa ttgtaaagtc tgaattttta
     6961 agagataata aagattttgt tgattctttt gtaggtcaat tatcaaatag tatagattgg
     7021 gcaaacaaaa atcctgaaga attaggtgca tattctgaaa aaataaaaat atctactgaa
     7081 tcaaagataa taggaaaatc tcttgaaaga gctaatttaa aatatattcc agttaaggac
     7141 atgattaaag attataaaaa ttactatgag aaattagcta attttgatga taagacatta
     7201 ggaggcaaag taccagatga agcaatatac tttgttgaga aataaaaaaa ataaagaaca
     7261 atttatagat aaaatggagg taacactttc ttgtgttatc ctcttatttt tatggcaaat
     7321 tattgcttta aaaattgata atgatatttt tttaccaaca gtaggtcaag tatttaatag
     7381 tataaaagag attatgctaa attctagttt ctatatagat atactttact ctatggggag
     7441 atgttttttt agttttttac tggctatgat ttttgccatt atactttcaa tagtatctta
     7501 tttaaataga ttttttagaa acttattaaa gccaatcaat gctttgacac gttcaatacc
     7561 aactatgata ttggtagtac ttgcacttat ttggtttgaa aaggatagta ccccttttat
     7621 agttggattt actatagttt ttcctatatt gtatgataac gttttgggcg ctatattgaa
     7681 tatagacaag aacttattag aaatggctaa tgtgtataaa ataaggttta tagataaggt
     7741 gttaaaaatt tatttaccag ccataaaatt tcaaattata tctatactag tatcaacatt
     7801 ctctttaagt ttgaaagttg ctatagcagg agaggtatat agtcaaccta catatggtat
     7861 tggaactatg atacagactg aaaaaattaa ctttaataca tctggaatat ttgcatggat
     7921 aattattgtt cttttaatat ctgctatttt acaaatagcc caaaagtttt tagcaaggag
     7981 agctttttta tggaaaagat aaagttgagt attgaaaata taaataaaag atatgatagt
     8041 cgtattatat ttagagattt taatattgat ttttatgtaa atgaggtaaa ttgtatcctt
     8101 ggaaaatctg gttgtggaaa aactacactc ttgaacataa taagtgggat tattaaaaat
     8161 gacaccaaca atctaaatat caaagaaaat ttaaatagag taggaaataa gcttgaagct
     8221 agttacatat ttcaagatga tagacttata gactggttaa cagtagaaga aaatataaag
     8281 atagttgtaa ataaatacta taataaaact caattaaata aaatttgtga tgaatacttg
     8341 gaattggttg gaattagtga ttataaaaaa ttctatcctc agatgcttag tggaggtatt
     8401 agacaaagag taaatattgc tagagctttt atatatccat caaaaaacat tataatggat
     8461 gaacctttta aatctattga tgcaaagaat acacagctta taatggataa tttcagaaat
     8521 atattaagaa aagaaaagag aactgtatta tttgtaactc ataatattga ggaagcattg
     8581 tttttagcag ataggatatt tattttagga gactctccaa ttagaataaa aaaaatatta
     8641 aaaaattcta aggaattgga aaaaaatgaa gttttgaagt tgatatagag ttataataat
     8701 actgtcgttt taaaatatat ttggttaaaa tctataagac tatattaaaa tagtacagaa
     8761 tattcaaaac tgtgtataat gttcgtattt tataaaaagg aagtgaatgt atggttaaga
     8821 ctaatgctat gagaatatta gattcaaata agattgatta taaagtaatg tcttatgaag
     8881 tgaaaagtga acatgtggat ggtgttgagg tggcacatga tataggaaga gatgtaaatg
     8941 aagtgtataa gacattagta actcaaggag ttagtaagaa tatatatgta tatgtaatac
     9001 cagtacatga aaacttagac ttaaaaaagg ctgcaaaagt agctaaagag aaaagtgtag
     9061 agatgattca tgtaaaagat ataaataagc ttacaggtta tattagaggc ggatgttctc
     9121 ctataggtat gaaaaagctt tataaaactt ttgtaaatga aagtgcaaag aatttagata
     9181 caattattgt gagtgcagga aaaataggat atcaaataga actatctcca tttgatttac
     9241 aaagacttat aaaagtagaa tttgtagatg taataaaaaa ataagaatta catataaaat
     9301 atagagctta tattcttaat aataggtgtt gtaatattaa taaaatgaat aataatttta
     9361 aaataaatat tcagttactt atgtgtaatt ggtataaaaa tattgagaaa ttttaaaaac
     9421 aatggtaaag tgtaagtata atcacgaata ttttttataa agtaatggag ggatgttcgc
     9481 ttgagaaaaa taaaatctga acaaatcgtc gagcaggtaa aaaaactttg tatagaagcg
     9541 agcctatatt taggagaaga tgttttaagt tgtataaaag aaaaagcgaa aagcgaaaag
     9601 agtgaagttg gaaaaaatat attgaatata ttagttgaaa atgctgaaat agctaaagaa
     9661 aaaaatatac caatatgcca agatactggt atggctgtat tttttgttga aataggacaa
     9721 gaagttttaa ttgaaggaga cacacttact gatgctataa atgagggagt aagacaaggg
     9781 tatgaagaag gctacttaag aaaatctgtt gtaagtccaa ttaacagagt aaatacaaaa
     9841 gataatacac ctgctgttat tcattatgat atggtaaaag gtgataaaat taaaatagaa
     9901 tttgcagcta agggatttgg aagcgaaaat atgagtaaga tgaaaatgtt aaagccatca
     9961 gatggattgg aaggaattaa aaaattcata atagatacag tttcagaagc tggacctaac
    10021 ccatgccctc ctatggtaat tggagttggt ataggtggga ctgtggacaa atgtgctcaa
    10081 atagctaaaa aggcactttt tagagaacta ggtgaattta ataaggacga aaatatagca
    10141 aaacttgaaa gtgaactatt aacagctatt aataaacttg gtataggacc tcaaggctta
    10201 ggtggtacta caacagcttt gggattaaac atagagactt ttcctacaca catagcaggt
    10261 ctacctgttg ttgtaaatat aaactgccat gcatcaagac ataagaaggt agtaatttag
    10321 gaggaaaata aaatgataaa aataactaca cctgtaaatg aaattgatat agcaaaatta
    10381 aattgtggag atacaattag tttgagtggt atactttata cagcaagaga tgctgctcat
    10441 aaaagattga tagattgtat aaataaaggt gaagaattac catttgacgt atatggtcaa
    10501 ggaatatatt atgtaggacc tactcctaca aagccaggag aagttatagg tgctgcaggt
    10561 ccaacgacga gttatagaat ggatgatttg actatacctc ttttagaaag aggtcttaga
    10621 ttgatgatag gcaagggaaa aagaagtgat gaagttatag aaggtatgca aaaatacgga
    10681 gcagtttatc ttgctgcaat aggaggagct ggagcgtata tttcaaattc aataaaatca
    10741 tgtgaaatta ttgcatatga agatttagga gctgaagcta taagaaagat tgtagtagaa
    10801 gaccttaaac ttacagtagc aatagatagc tatggaaata atatatatga gcaaggtcga
    10861 gcaatttatg aatgtaaata atgtttagaa ataaatatga atatcaaaat taaaaatagt
    10921 tgtgtatatt ttaaggagga aaattgatgt ctaaggatta tgcaaaattg gcattagaaa
    10981 tgcatgaaat caacaaaggg aaagtaagtg tagaaagcaa ggtagaagtt aaaactaagg
    11041 atgatttatc aacagcatat acaccagggg ttgctgaacc ttgtttaaaa atacatgaaa
    11101 atcaagatga tgtttatata tacacttcta aagggaatct agtagcagta gttagtgatg
    11161 gaagtgctgt acttggatta ggtaacattg gtgctgaagc atctatacct gttatggaag
    11221 gtaaagctat attatttaaa caatttgcag atgtagacgc ttttccaata tgtttaaaga
    11281 ctaatgatgt agatgagata gttaaatctg tagagttgat ggagcctgta tttggaggta
    11341 taaatttgga agacatatct tctccaagat gttttgagat agaagagaga ttaaaaaaat
    11401 ctttaagtat acctgttttt catgatgacc aacatgggac agcaataata gttgcagcag
    11461 ccataataaa ctcaataaag ttaattgaaa ataaaaaaat agaagattta gaaatagtta
    11521 taaacggagc aggagctgct ggtatagcca tagcaaagat actacttaat atgaatgtta
    11581 aaaatataat cttatgtgat agaagtggag cattggaagc tagtatagaa aatctaaact
    11641 atgttcaaaa agaaatgtta aaagtaacaa atataagaaa tgaaaaagga cctttaaaag
    11701 atattataaa aggaaaagat gtatttattg gtgtttcagg tccaggagct gttacaaagg
    11761 aaatggttga aagtatgtct gagaagccaa taatattggc aatggcaaat cctactccag
    11821 agataatgcc agaagaagca aaattaggtg gagcatttat aatgggaaca ggtcgttcag
    11881 acttccctaa tcaagtcaat aatgtactgg cttttcctgg aatatttaga ggagcattag
    11941 atgttaaggc taaagagata aatgaagaaa tgaagatagc tgctgcatat gcaattgcta
    12001 atacaataag tgatgaagaa atatgcccag agtatatatt accagatgta tttaataaga
    12061 atgtagtaaa aaatgttgct aaggcagtta aagaagcagc gataaaaact aaagtaaata
    12121 gaatataaat ttttataact tattaaaaac tagaaaagta taaaagacta gtgaaattat
    12181 gtacagtggg atgattttat tagtcttttt attttaaata tgacacaata atgtcatatt
    12241 aagcttgata taattttaat atggttagga gccaaagaaa aatataagga gtgatttaaa
    12301 atggaagaaa ctaaattttg ccaatgctgt gcaatgccaa tgggacaaac tgatgaatta
    12361 tatgggacaa ataaagatgg aagtaaaagt actgattatt gtagttattg ttttaaagat
    12421 ggtgagttta cagctgatat aagtatggaa gagatgatag aagtttgtat ccctcatatg
    12481 cttcaaagta ataaggatat gactgaagat gaagcaagaa caatgatgaa caatttcttt
    12541 ccaacattaa aacgctggaa ataattttat gcaaaattag ttatatgcaa aacatgaaat
    12601 atggtgttga gaataagggg tggtgtgctt tatagcatac cacctgtttt gttacttgct
    12661 agttcagtta ttcttgtatg cttaaatatg ttctcatctc tctttctatt ttaaattgta
    12721 aaaatctaaa atatgttatt tatattctac ttctttatcc atgtcttttt ctacctcaag
    12781 tcaaatacaa ctacaaaatc atcattttca attcactgtt taatagaatt aacagataaa
    12841 gagttataaa attttctatt ttttatataa aataatacag gtcaagctga cttctagcta
    12901 cttgggatag tgtatatatt tatgatagtt ataggagtaa taccaatcat tagactgttg
    12961 atttgtgtag tcttttgtaa aaacatttgt tttaatatat tgagtttttg aaaaagtaaa
    13021 attataatta taataaatta agtgtaataa tgtattagaa gtaaaaataa ttaaaataga
    13081 ggtgattaaa tgagcagtat attgttagtt gaagatgatt taagcttgat atatggatta
    13141 gagttctcta tacaaaaaag tggatttagt atagacatag caaggacagt aaaagaagct
    13201 atgcaaatgt atgaggaaaa aaattatgac ttattgcttt tagatgtatc cctacctgat
    13261 ggtaatggat ttcagatttg cgaaaaagta cgagaggttt ctaatatacc cattatattt
    13321 ttgactgctt cagatgaaga ggtaaatgta gtgatgggtc ttgatatggg tggcgacgat
    13381 tatataacaa aaccttttaa attaaatgaa ttaatttcaa gaataaaagc attacttaga
    13441 cgttataatg ttgcaagtaa tgtgaatgaa ttaagttcaa ataatattac tattaaatta
    13501 cttgaaaatc gtgtttttaa aggtgaattt gaggtggaac ttactacagc agaatataaa
    13561 ttattgtgct tatttatgaa aaataaaaat attgtactta ctagaaaaaa catattggac
    13621 aagttatggg atggaaatgg tagctttata gatgacaata cattatcagt atatgtaaga
    13681 cgattgagaa ataaaattga agataatcct gaaaatccta agtttctatt gaccgttaga
    13741 agaatgggtt ataagtggaa tgtaattaag tgagggtatt aatatgaaga tattttctaa
    13801 taaagatata aaaatatttt ttttaattct tatatctatt ttagtaatgt ttattatagt
    13861 agggcaaata gtggttataa gtataactaa caattataaa aaaacgttga tagaacatga
    13921 ttataatata gctggatact tatatagtat aggtgttgat aaatctaaaa taccatcagc
    13981 atttgttgca catgaagata aatatatttt aaaaggaaaa gaaatactag atacagctgg
    14041 atatggattt gatatagatg ttagctttac accaagtgta aaattgtttc aaagtaaata
    14101 tataaaaact atgtctatct atttattagt attttttact atgattattt tcatactata
    14161 tatgtatttt tttaggcaac aaagtaagat agaagaggct agttataaaa ttgatttatt
    14221 tatgaatgga aatataaatg aaagactaaa tacatatgaa gaaggtagct tatcaaaatt
    14281 atttagttca atagatgtta tgtcgacatc tttaaataca catatattaa aagaaaaaca
    14341 gagcagagaa tttcttaaaa atacaatttc ggatatatcg catcaattaa aaactccact
    14401 tacagcttta ataatgtaca atcagatact acaagaagaa agtcataata gtgatgtcgt
    14461 tgaagctttt gtacaaaaaa gtcaaagtga actagaacgc attgaaacat tgattaagaa
    14521 tttactaaag attacaaaga tagattcaaa aacaatagtt ctcaataaaa ataatgttaa
    14581 tcttaaaaat ttaattgtca aaattttgta tagctttgaa actagggcag aaaaagaagg
    14641 aaaggttatt tctataaatg gttcagaaaa tacattgttg ttctgcgatt atgaatggat
    14701 gtcagaggct ttaagtaatc ttataaagaa tgcattagat aatacaaaag agaatgataa
    14761 aataacgata gagtggtttg agacgactat aaccaccatt gtttcagtta aagacactgg
    14821 aaatggaatc catgttgagg atattcatca tatatttaaa aggttttata gaagtaagtt
    14881 ttcaaaagat aatcaaggtt taggactggg attaccacta gttaaatcta ttgtggaaca
    14941 acataatggt actatttctg tagaaagtaa actatcacaa ggaagtacat tcaccataag
    15001 ttttttaaag cttactaata tgtaagataa aatacatctt gcagtaaggt atatagatta
    15061 ttattatatt aatcaattag aaaggtgaga gagaaaatgg atattcttgt ggttaataat
    15121 ttatgtaaaa catatggaaa tggatataca aaagtagagg cattgaaaga tgtatccttt
    15181 acagtttcaa aaggagagtt tgtgactgta gttggagaat ctggttcagg aaagagtaca
    15241 ctattaaatc tcttaggagg tcttgatact ccaacatcag ggagaatatt tattgatggt
    15301 aaagaaatat gttcaatgaa agaggaaaaa cagactattt ttagacgtcg taacataggg
    15361 tttatatttc aggcatataa ccttatacca gaactaactg tggagcaaaa tataatattc
    15421 ccattgttat tagattataa aaaaccagat actatttact tagatgaagt attgactatt
    15481 ttaggtctta aagataggaa aaatcatctt ccaaatcaat tatctggtgg tcaacaacag
    15541 agagttgcaa ttggaagggc tttgattaca aagccaagta ttatactggc agatgagcca
    15601 acgggaaatc ttgacagtaa aaatagtaat gatgtaattt cacttttaaa agtgactgca
    15661 gaaaagtata atcaaaccat tattatgata actcataata cgaatatagc ttctacagca
    15721 gatagaatac tacaggtttc tgatggtgtg cttacagacc tgggggtgaa tagagaatga
    15781 gaagctactt agaattagta ccacaatatg caaaagtaca taagaaaaaa aatagaacta
    15841 caattttatg tattattatt gcagtatgct tagttactgc tatctttgga cttgcagata
    15901 tggctataca atgtcaaaag atacaattta ttaaagatga tggaaattgg cacatagtaa
    15961 ttagaaatat tgatgaaaag tttatatcag aaataaatag tagagtagat atagctcacc
    16021 atggtagggg gcaagtcgtt gacagtggag agtttaaatc aaaggagatt ttgatacaag
    16081 gtttagatga agaagtagca aaacaattta acttagaaat aataaggggt cgttatccta
    16141 ttggggagaa tgagacttta atagatgagg atgcagttaa aagctttaat ctaaaaatag
    16201 gagattttat caaaataaaa ttagcagatg gtagaaataa aaattataag atagtaggtg
    16261 aatattcatc aatatcaagc ttaagagcta cagataaaca tggattaata ctttcaatat
    16321 tgggtacaca agctattaaa aaatcagaaa cgtacgatta ttattatatt acatttaaag
    16381 aaaaggttaa tattagaaaa gccacttctg atattaaaaa taccttcaat ttaagtgata
    16441 aacaaatcgg taaaaatgaa agattacttt ctattatagg tcaaggcgac tctgactttt
    16501 ctaaaccact gtatttaaca gcaggattac tttttgtact tgttttagta gcaagtatta
    16561 tcatgatata taatagtttt aacatgagtg taattgagag agttaaattt tttggtctgt
    16621 tacgttgtct agggtcatca aaacatcaag ttaaaaaatt tgttgtttta gaaagtttaa
    16681 ttttaagtat aaaagctatt ccaataggct tagtattagg aagtcttgta actattatat
    16741 cttctatatt tcttaagtat gttaatgagt tattcagctc aatgccaatt ttaaaagtta
    16801 gttttattgg tattgcattt ggaataattg tagggttttt aactgtaata ttatcagcta
    16861 ttattccagc aaaaaaagct tcccgtgtat ctccacttag cgctgtacgt gggaatctaa
    16921 tgtccaaaga aattttaaat aacgggaaga caagtaaagt tgcaaataca ggaagtttta
    16981 aaattgagac ttctatggga ttaaatcatg ctttttcaag aaagaaatct tttgtactta
    17041 tgacttcttc atttgccatt agtattatac tatttttagg ttttagtgtg cttatagacc
    17101 ttatgtatca aggacttaag cctatgaagc cagaagctcc tcatatatct attgttgacc
    17161 ctaattttaa gtctgtttta actaaggaag atattaatga aataagcaat atcaaaggag
    17221 taaagaaagt atacagtaga atgatgacgg atatagaagc tacatataat gggaagaaga
    17281 caaaatcaca attaatttct tatgaaaagt atcaatttaa ttgggcaaaa aaatatctat
    17341 taaaaggaga agttaatgaa aataaactac agtcagaaaa ccttgcatta gtagaagagg
    17401 ggcatggatt tgatatagga gataagatat atattaaaaa tagaaatgct gaaaaagagt
    17461 tagaggtagg aggtatactt tcctcaattc catttgaggc taaagataaa tatattggaa
    17521 atattataac atctgaaaat acttttacga atataacagg tataaagggt tatataataa
    17581 tggatattca ggttgataaa gatactcctg gagatttaat tgaaaatata agacgtgtag
    17641 tagatgataa cttagaggtc agagataaaa gacaaagtaa cttagaggtt aaaaattcgt
    17701 tttatactat ggcaacattt gtatatggat ttgtgtttat tattgcgatt ataagcatgt
    17761 ttaatatcat aaatagcatg aatataagtg ttacaagtag aaagaattac tatggtgtta
    17821 tgcgtgcagt aggcatatcc aacagacaat taagaagaat ggtaatagta gaggcaggtt
    17881 catatgcaat gagtggttgt ttattaggta gtatactagg attaatgtta cataggtata
    17941 tgtttatatc gttagtaagt tcaatgtttc atttagagtg gcaagtacct tttaatttac
    18001 tacttatcac tgtactaact atgataataa taactttatt atcagtaaga aaaccagtca
    18061 aaaagatttg tgaattagat ataatagact caataaatgc acaataaata tagctgttga
    18121 tttaaattaa aaaaacgaag taaaaatgaa atagaaaata tttttcattt ttacttcgtt
    18181 ttttatatta taaaattttt gttatgttac aaaatttcta taaagatgat gtgaatctaa
    18241 acattatatg acaacgtgag catttaagtt aaaatatttt aaatatacta ttttagataa
    18301 gttccttctt catcttgata aattaatcct tttttcataa gcactccaag agctcgttta
    18361 aaatttttct tacttgaatt aaataatata gaaatatctt tagggtcaga tttatcatta
    18421 aatctcatat atccatcaga accctctaaa taacttaaaa tcttattttc taaagtatca
    18481 agttcatcct ttctatttcc tctaggagaa agaccaagtt ttccatcttc atatattttt
    18541 atgacatgta aattttcaag aacatcacca gcttttagtt cagtaaagta ctcattatga
    18601 agtattacac cagcatattt attgtctaca catatcattg cagaattatt agtttgaaat
    18661 ccatatacaa ctccagttac aatatctcct acattgtaag tatggtctgt taataaatat
    18721 gaatctatat ctgtagtagc agcaattctt ttgcttttgt ctaaatatat ataaaataaa
    18781 tatttttcgt ctctaaatag tggataagtc ttagctttaa aaggaactag tatgtcttta
    18841 ggaagtccca tatctataaa agtaccaatg tccgtattat caactacttt taaatgtgct
    18901 acatccccaa ccttagctaa aggcggtatt aaagttgcag cagttctgtc atcagaatct
    18961 ttaaatatga aagcatttac ttcatcacct atgtttattt cattttttcc gattaatcta
    19021 ttatgaagaa gtatatcgtc ttttgtgtta ttagtttgtc catccaaaaa atatccaaat
    19081 tcagtttttc tttttactgt aagtttatta aaatcaccta tgtttatcaa attaaaatca
    19141 tcctctcatt ttatatttat aatttagcca taatatactt atgtagtagt ttgtcacagt
    19201 atctatatta gtattagtga aatttacaat aaataatata gttatttatg tatttttcaa
    19261 ttctctagct tcttatatag tataaactcc aatttctttt ttgtctttag gttttactaa
    19321 aatttttaca aaataagtta aaaagtattg aaataaaatt tcttttaaag tataattggt
    19381 atataccaaa attggtatat accatatcga aaagtggtga ctatatgaaa atagtaaata
    19441 aatctagtaa tataccattg catactcaat taagttcaat aataagagag atgatagaaa
    19501 ctggtgagct taaagagggt gatgcaataa tgccagaaag agaactttgc aacatacaaa
    19561 atgtaagtcg tatgacagta aataaaacca ttgttggatt agtcacagaa ggacttcttt
    19621 atagggtaca aggtaaaggg acattcgttg caaagcaaaa aaagaagtat cagttttcaa
    19681 atgtaaaagg ttttactgat gttatgaaag aaaagggagt aaacataaaa acggatatat
    19741 tatcctttga gatggaacta ccagatgatt tagttaaaag aaagcttgga ataagtgata
    19801 atactacaaa tatatataag attgtcagac ttagatatac tgatggagag ccatttggat
    19861 tagaaatagt atatctatca gaagaaatgt gtaaaggtct aacaaaaggg atattggata
    19921 attcttcatt atatagggtt ttaaatgaaa aatatggcta taagatacaa aaagctgaac
    19981 aagtaatgga gccagtaata ctttcagatg aagaaagtaa gcttcttgaa acagatgaag
    20041 gtgctttagc tcttaaactt catagaaatt cctataatag agaaggtagc cctatagaat
    20101 ataccatatc aatatttaga acagataaat atcaatatga aatagtattg agtgagtagg
    20161 tgaataatat gaaatgttta attaatggaa agataatatt aaaaaatcaa atcttggaaa
    20221 ataaagtatt agtatttgat gaaaaaataa ttgatatagc tgatagtgta ccaaaagatt
    20281 gtgaagttat agatgctgat ggaaaatata tatctccagg gcttattgat attcatatac
    20341 atggaaatat gggaaaagat acaatggatt cgactgatga atctattgaa acaatttcaa
    20401 aatcaattat gagacatgga gtaacatctt ttcttccaac tacaatgact atggataaag
    20461 aacatgttta tgatgcactt gaagttatta aaaaagccca aaatagaaag cttgaagggg
    20521 cacaagtatt aggagcacat ttagaaggac cttttataaa tgagaattat aagggagcac
    20581 aaaatgaaaa atttataata aattcaaaat acgaatttat aaaagaatat aaagatgtta
    20641 taaaagttat aacttatgct ccagaaaaag atattgattt tgattttact agagaaataa
    20701 aaagatgtac agatatagtt ttatctattg gtcatagtaa tgcaaattat gaccaagcta
    20761 aagaagctat aaatttagga gtaactaata taactcacat gttcaatgca atgactggtt
    20821 taaaccatag agacccaggc gttgttggtg cagcacttac aactaatgtg tacagtgagc
    20881 taatagcaga tacaatccat ataaataaag atttatttca atttatacta aataataaag
    20941 ggaaagaaag actgatttta ataacagatt ctatagaagc tggtggtctt gaagatggca
    21001 attattctct tggaggtcag aaagtcatag ttaagggtaa tgaagctaga cttgaaaatg
    21061 gagcattagc tggaagtgtg ttgtctttaa ataaaatggt atttaacttc ttagataata
    21121 caaaccttaa agtgaatgaa gcaattaatt tagcttcttt aaatccagca acatctttgg
    21181 gaataaatga caaaaaagga agcttagaaa taggtaagga tgcagatata gctgtatttg
    21241 atgagaattt agattgtaaa atgacacttt gcttggggga cgtagtatat aaaaatatat
    21301 agtatacaaa acaaacttta aagacagtaa aaacaatata aaaaataata aattaaactt
    21361 acattagtta aagtagtagt taaaatttag gaggaataag atgagagtat tagtgtgtaa
    21421 agattatgat ggaatgagta aaaaagccgc tgaaatgata gcagctcaaa tagttttaaa
    21481 accaaattca atactgggac tagctacagg aagtacacca gtaggtatgt atagagattt
    21541 agtaaaaaaa tacaatgata atatagtaga tttttcagat gtgatgagct ttaatttaga
    21601 tgaatattat aagttaccaa tatctaatga ccaaagctat gattatttta tgaaagagaa
    21661 tctatttaat catgtaaaca taaagctaga aaatactcat ctaccaaatg gaatggctga
    21721 tgatattgaa aaagagtgtc tgaactatga agcttctata gatgcagctg gtggtataga
    21781 tgtacaagta cttggaatag gtcgtaatgc tcatataggt tttaatgaac ctgatactaa
    21841 atttgcaaaa agaactcatg tagttgaact tacagagtct acaatagaag ctaatgcaag
    21901 attctttaaa tcaagagaag atgttcctaa aaaagctgta agtatgggaa taggttcaat
    21961 attgaagtct aagaaaatat tgcttttagc ttcaggagaa gaaaaagctg atgcagtata
    22021 taatactgtt tacggagata taactccaga agttcctggt tctatacttc aacttcataa
    22081 agacactata gttatagtag atgaagcagc agcaagtaaa ctgaatccaa aagattataa
    22141 attagtataa gaatagaatg tagtttaagt gaaaaatagc tatcattgaa taatcaaatt
    22201 tatttaatga tagctatttt tatttaaatt ttttacttct ttttatttaa attagttatt
    22261 attgtttaaa ttacttgctt attacttttt acgaaaactc gttatcaaga agtatccgaa
    22321 taagatgtta aaaattatta tgtttagtgg gattctatca agcataataa aattacctat
    22381 aattgggata ttaccaattg gaaacataaa gaagaataca ggcatcagtg atagtaaaaa
    22441 agatggaaaa caaagaagaa gtaatcttgg aatatcaata taccaactac catccttttt
    22501 gtattctcta atcaataatt cagttcctag taacaaacca ataccaccag aggaaattaa
    22561 attaataaaa atgtatcttt taaagtcttg catataacca gtgtgaaatt gagtatagaa
    22621 atcataattt aatttaacgg ctaaaaaata tataagcaat agaatgatta aaaataaaag
    22681 atatctaaga gcttttttca ttttaaattc tcccttcaga aatactttat tcagttttat
    22741 tttgttggaa tctgatttta tcatttagtt taagaaatcc ataatattag tgaagaatga
    22801 aataagtatt atatatgaat aaatattttt agaattaagg tgaactgtag tgcttaatat
    22861 aactataata ttaattgttt gaatattcaa taaaaagttt aaaaaatatc aattttgata
    22921 taaactgaat aaatacagtt gaatattaaa ttattatttt atcaaaaata tgcaaagtac
    22981 tacaccttca aatatcacct aaagtaatta aaaggcaatt aaagtgaagt agttcaagta
    23041 tttctaaaat gagtttaata aattctataa taatttattt tttgccttaa aattgcctta
    23101 aaatccaaac aattttaaaa ctaatgtact ataaaaagct ggtataattt aaatatagta
    23161 aaaaataaga tttatcttat ctattgggat ttaattattt aatcaatata tttataccat
    23221 ttaatttaaa taaaaagtct attaaggagt gagcttatga gtaagttaat ttatatagca
    23281 gatgatgaag ataatataag aaatttggta aagacattct taaaaaatga aggtcatgat
    23341 gttatggatt ttaaaacggg tgatgaactt ttagaacaat ttaatataaa ggagtgtgac
    23401 ttagtaatac tagatataat gatgcctggc tcaagtggtt ttgaagtatg tacaaaactt
    23461 cgtgagaaaa gtacagtccc aataatcatg cttactgcaa gagatacaga tatagattat
    23521 attacaggga taaccttagg tagtgatgat tattttacaa aaccatttag cccaatgtct
    23581 ttggttatga gagtaaaatc tatatttaga aggatagagt ttgaaaagaa acaaaattat
    23641 gataaatata gtaactcgat agatatggaa ttaaaatttg gtgatgtaat aataaataaa
    23701 aagaataaaa tcgttacaag taaaaatgta aatatagacc ttacaccaaa tgaatataat
    23761 ctattgactt atttgtttga aaatatagat agagcagttt ccagagatga attattaaac
    23821 aaaatatggg gatacgatat agaagttgag acaagggctg ctgatgatac agtgaagaga
    23881 ttacgtaaaa aaattttaga tacaaatatt ttaatagaaa ctgtatgggg gtttggattt
    23941 aggttgaagg agaaaagtta agatgaataa tggaaatgac aagaatagaa ttggaaagat
    24001 taaatccaaa tttaaattaa agttctcaaa gaaaaatata agcataaaaa ctaggatttt
    24061 gttgagcata ctttgtttga taattatagt atttatgata atattagtat cttttaatgt
    24121 atttcttgat acatatataa aaacaactgc gaatgaagaa ttgacgaagt ctacagaaat
    24181 agtagaacat atggatagta attttagacc tattaagcca ccacaagatg atggaaagct
    24241 tcctcccaaa gtattatcta attttatgag aaatgtacaa gataaagtta ggatggcaga
    24301 aacacaatca gatgctgatg ctatggtagt tgattctaag tataacctga tatttccaac
    24361 aagagaggat gatttcttaa aaaatgttga tgagatggag ctgattaggg agtgtattca
    24421 aaatgaaaaa ttagatttaa attcagatga aaatacacgg atatctacca gaaataagga
    24481 ttattatatt tcaactgtaa aaattactag tatatatggt gaacaagaca aatatcttat
    24541 actttttata gacatatcaa aaactctaaa tctagcacaa aagataaata ttgtattaat
    24601 atctgtaatg tgttttgctg gaatattagc aatatttaca gctgtgattt tatctgagaa
    24661 aattgctaaa ccgataaaag agttgtgtga gtttgcaaaa aaaatgggtc aaggagattt
    24721 caaaagaacc tactttgact tttcagataa agaattagta gagctctcaa ctgttatgaa
    24781 taagagtgct gagtatctgg ataagtatga taatgaacaa aaaatatttt ttcaaaatgc
    24841 atctcatgaa ttaaggacac cactcatgtc tattaaaggt tatgcagaag ctataaaata
    24901 taatgttata gatagtaaac atgcaagtga tataattctt gaagaaagtg ataggttaag
    24961 tgatatggtt gaagatttat tatacatttc taaaatagat aatataacta aagattttga
    25021 acttgtagaa tgtgatttaa gagaagtatt ttcaaattgt ggagctaggc aaaatgtaag
    25081 agctataaat aaggggataa aatttattta tgaatttgat gaagaaatgg ttttatttga
    25141 atgtgatgaa aaaaacattt ccaaagcatt tatgaatctt atagaaaatg ctttgagata
    25201 cgctaagagt gaaataaaaa tagtgtgtaa gtataatcaa aaaaatatag ttgtgataat
    25261 agaagatgat ggaattggaa tcaagaaaga agatttacct catgtttttg aaagattcta
    25321 taagggagta gggggaaatc atggaattgg attatcaata gttaaatcta ttgtaaataa
    25381 gcatggtggg cgtatatacg tagaaaatgg caaaaaagga gctaagttta ctatattatt
    25441 taaattgtaa aaaaattaga gaaaatataa agatgtttga agttgttttt tatatatatc
    25501 tgttgtatac tgttgaaaaa agaacaatat taagctgaca tatattacaa taattgacat
    25561 ttaaagtaaa tgcttaaata tagatacgaa aggaaaagta aaatctgaag tgtatttagg
    25621 tttaagtaag cttcttattt tataaaaaat atgtatgaaa gaacagctga tttttaatat
    25681 tacaaattta gtaacggttg tatttgaagc ttttgtcatc catatgtttt tatcagactt
    25741 tttaggtcag aaagaagggt atataaaagt tgtaagatat gctaaactgg gttttataat
    25801 atgtttagga ttctgtaatt taataacttt aaaccctaaa atcacaatgc ctttaatttt
    25861 tatccttatt ttttcaacat catttttata taaaggaaat ttaaagacac gattgtttac
    25921 tactgtttta ttaagtatat tctttatact gtcagaaatt gtagttacaa gtatttttgt
    25981 tttatttgta aaagaaggct ttgaaataat gcttgaaaat aatagtataa gagtattggc
    26041 gacaatttta tctaaaattg tctttttgtt gacttgtaaa attatttgtc tatttaaaaa
    26101 agatgtacat ttagatatgc ccataaagta ttggctccct ttatttttaa tacctatatt
    26161 tagtttattt ctgtctgttt ctatctttga tgtaagtaaa ttttttagtc ttgaaagttt
    26221 aaaatttcta agtttaatat ctagtgttgg cattttatat attaatttta ttgtatttta
    26281 tttatttaaa tttattatag ataaaactaa actatctatg aaatatgaaa tacttgaaaa
    26341 agaaataatt cataaggaag aattaagact tagtaatgag tgttataaaa ttattgttga
    26401 acagactgat tctgtcgttt tcgaatggaa tatcaaagaa aataaatcat ttgtatcgca
    26461 ggcttggact gaaaaatttg gatataacaa tgcatgtaag aatattttta aagaaattaa
    26521 agataaagac ttagttcatt ctgaagataa agctatattt gaaggttttc ttgaaagtat
    26581 taaaaaaaag aatatacaca gtcaagcagt atatcgttta aaaaaatcta atggtgaata
    26641 tatttggtgt agaacatcaa ttacaagcat ttataatgat gaaaatgaac ttttaagagt
    26701 tgtaggagta attgtagacg tagatagtga tataaaaaaa tatgaagagt taagaactag
    26761 agcagaaagt gactcattga ccaatatata caataaaggt acatttgaaa aattagtgga
    26821 agaaactata gttatgaata caggtgataa aaaagatgca ttattcatta ttgatttaga
    26881 tgattttaaa gaaataaatg ataattttgg tcatccattt ggtgattttg tactaaaaac
    26941 atttgctgat aagatacaag ctagttttgg taataaagac ttagtcggaa gaattggtgg
    27001 agatgaattt gttgtatata tgcaagatta tgttacagaa gtaaatttgc ataaaaaagc
    27061 taaagaatta aatagagtac tttcggataa ttacactgat ttgagtttta gttttgattc
    27121 ttctgtcagt ataggtattg caaggtatcc tcaagatgga acttcatttt ttgaattgtt
    27181 taaaaatgca gatagagcac tttatagcat aaaagcatca ggtaaaaatt catattgttt
    27241 atttgaagaa gaactatatg tacagtgaat ttgaatttag attttatgtg agagtaagat
    27301 ttatatatac ttgtggctgt ctgatttata aaatatgtta ctttgtatat ttttatatgt
    27361 ttcagtaagg ttaattaaca taagcaaagg tgtaagtaaa tttatattag tttaagttta
    27421 cttacacctt tataaaaata aattttgtaa atttaaacag ttggttttat aaggattttt
    27481 atttatttta atatcttaga tattcctttt tgtattcctt agagaaaata aataatgaaa
    27541 ggagtacaga aaaaattaaa catcctaata taccacttga attaagtctt aaagcattaa
    27601 agtttaaaaa agcattattt aaatcggtat ccaaaagaaa aggatgcttt gatttgctat
    27661 atatggaaaa attaaaaata tattcataat caaatttata aaattaatat ctttccatcc
    27721 taacattaca tttacttaga ttaattatta ttataaaaat aaaaatacaa ataatagatt
    27781 catttacatt cttaaatgat taaagctctt taccctttaa acatgcataa catatcgtta
    27841 taattccagt aaataagact aaaatgccca ttcctaaaat tgcagtttca tcatctatta
    27901 ctccaaatgc ttttaaagta acttatttcg ctttgtataa taataatttg tctcttttta
    27961 tattttaact tctgctgaga tttgagttag atattcgtta gaatctcgca cacttatatc
    28021 atatagaaga tattcttcat aaacaaaatc cccaatacgt aaattattct gattaaaaaa
    28081 atttaataac ttttcataag ccttgtaaat agtttcataa ctacctttat gataagcagt
    28141 tacataaagt ccctttggtt tgattgatac aggatatttc ttgtactctt tattaacttt
    28201 tgtaaataaa tatgaatatg attcaaagtc tttattaatt atatcttcac ctttaatgat
    28261 tgagccaatc gtaccatagt cactcaattc atagttgtcc ataaagttaa tacattcata
    28321 taaaaaattt tcttcctcat ctcctaaaaa ctgttcttta tatgtaatag gtgttttgac
    28381 caagtactct tcctcatgtt cttttaaagt aatagtattc gcatctatat tacaggcatt
    28441 tttagtgaat gaaatagtag attccattag agcttgaata ttatttagtt tttcaatttc
    28501 atttttaata tcaatggttt tcttttctaa aagctcaatt agtaaattag gtgttctttt
    28561 gtctatataa gctttaattt cttttaaagg catttttact tccctaagtg aagaaattat
    28621 accaaaaatg ctaagttgat ggtatgagta gtatctatat ccattttctt tctttaattc
    28681 tggtgagaaa agacctatat catcataatg gaaaagtgtt tttttattga ttccacaaat
    28741 ctttgcaaat tctccagttg taaaataatt ttttgaaact tgactcataa ttataattcc
    28801 tccttgacta tcctgttaca gtatagttta tcatagtatt ttgtaaagga gtgtgattat
    28861 atgaaaaaat taattcattt tttaaaacca tatagagttt taattgttgt agttttgata
    28921 tttacgtttt tacaaacact tggaactttg tatataccaa cacttacagc aaatatagta
    28981 aacaatggtg tagtaaaggg agatatagat tatattgtaa aaacaggttt aataatgatg
    29041 atagtagctg gtataacagc tttatcagct gtgttagttt gtaaagtatc agcaaatctt
    29101 tcatctggat tttgtagaga tattagagaa gcagtatttg taaaatcaca agatttatca
    29161 ataaatgatt ttaataatat aggtacagca tcaatgatta ctaggagtac tagtgatatt
    29221 actttaatag gtcagtctgt gtttatgttt attcaattgg tattaccagc accaattata
    29281 actgtttctg gtctattctt agcatattct atagataaag caatgacaat tattattgtt
    29341 gtagtaatgt ttttattcat gctttcagca tttttagttg gtaaaaagct tataaagttg
    29401 tttaaaatga tgcaaataaa gatggacaat atgaataggg tattacgtga ggtagtaact
    29461 ggagtaagag ttataagagc ttttaatagg gagcattttg aaaaaaagag atttgataga
    29521 actgcaatag attattctga aacagcaatt tcaataaata aagtatttgc agtacttatg
    29581 cctattgtaa tgttaataat gaatttaggt atagtaagta ttatttggtt tggtgggatg
    29641 agagtcagta atggaaatat ggagataggt catataatgg cacttattga atattgtatc
    29701 ttaattttat tctatttaat catgggagta atggtattta tgtacatacc tagagcaggt
    29761 gcatgtgcag atagagtaaa tcagatatta gatatagaac ctgaaattgt agatggaaat
    29821 ggtcgtaaag atactgtctc agagagggga catttagtat ttaaaaatgt aacattttca
    29881 tatgcacaat cagaagaacc tgtgttaaat aatataacat ttgaagcaaa atctggagaa
    29941 gtaactgcaa ttataggaag cactggctca ggcaaatcta ctattgcaaa tataatacca
    30001 cgtttttttg aaattcaatc tggagaaata tctataaatg gtcaggatgt taagaagatt
    30061 cctcaaaaag aacttagaga taagattgga tttgtgccac aaaaagcttt tttatttagt
    30121 ggaacaatag aagaaaatat aaggtatgga aaagaagatg caagtattga agaaataaag
    30181 catgctgcaa gtatagctca agctgatgaa tttatttctg atatggaaga caagtatgac
    30241 tcatttgtag cacaaggtgg aaataatttg tcaggtggtc aaaaacagag aatatccatt
    30301 gcaagagcgt tagttagaaa gcctgaagta tatgtctttg atgatagttt ttctgcatta
    30361 gattttaaaa cagataaaag acttagaaaa gcgttgaaaa atgaaatcaa agattcatca
    30421 gctataatta tagcacaacg tataagtaca atcatggatg ctaatcagat tatagtttta
    30481 aatgatggaa aaattgtagg tattggaaaa cataaagatt tacttgaaaa ttgtgaagtt
    30541 tataagcaaa ttgcggattc acaacttagt aaagaagaac ttgcataaaa tgaagaatta
    30601 atctgatatt tggaggtgta tgatatgagt gaaaaaagaa tagatgaaca agatatagaa
    30661 gtacttagtt ttgaagatgg catgtcagca gaaaaagtta aggatgcaaa aaaaactact
    30721 aagagattat taaaatatat ggcaaaacaa aagtttaaaa tattaattat ttttatttca
    30781 gtattgataa gttcagcgct tacagtttta gcacctatgg ttatgggaaa agctattgac
    30841 caactattta atggaataaa aactgcagtc caaacaggta caaaattcag tgtgaatttt
    30901 agtactatgg gggggatagt atcaatactt ctagggttgt acttaattag tgcagtattt
    30961 atatatattc aacagtatat tatgtcagga gttgcacaaa atctagttct tagcatgaga
    31021 aaagatttaa gtgataaact caataaactt cctcttaagt actatgattc tcataaaaag
    31081 ggggaaacac ttagtatagt aacaaatgat ttagaaaaag tagcagatag tttacaagaa
    31141 ggattaatgc aacttattac agcagtagtt acagtagttg gttctattgt aatgatgata
    31201 agtataagtg taccacttac aatagtatca gctataacat tacttgtttc attgggtatt
    31261 actgttgtaa ttgcaagaaa atcacaagaa agattctctg aaaatcaaaa ggcactagga
    31321 gagttaaata gcaatataga agagatattt actggtcaaa tagtggttaa agcatttagt
    31381 aaagaaaagg atactataag aaactttaaa atattaaatc aaaatcttta taatgcaagt
    31441 agaagagcac agttttcgtc atatgcaata tctccaatta ttagatttat aaacctaatt
    31501 ggctatgtta ttatagcagt tgtaggtggg atatttgcat caactggagc aatgactctt
    31561 ggtagtatac aagcgtttat tcaatatgta aatcaagcat cagagcctac tacagaaata
    31621 tcttatattg taaatatgct tcaagcagca atagcatctg cagagagagt ttttacagtt
    31681 atggatgagg tggaagagat aaaggatgaa gaatcttcaa aggttattag catgcctaaa
    31741 ggtaaagtac aatttgagca tgttaaattt ggatatagtg atgattttat tcttatgaaa
    31801 gatattaata tcaatctaaa tgcaggagac aagattgcaa ttgttggacc tacaggagct
    31861 ggaaagacaa ctcttgtaaa tttacttatg agattttatg agatacaagg tggaagaatt
    31921 actattgatg gtgttaatat aaaagactta aagcgtggag aacttagaac tatgtttggt
    31981 atggttcttc aagatacatg gctgtttaat ggaagtataa aagaaaatat tgcatatagt
    32041 aagtcagatg ccacaatgga tgaaattgta agagcagcaa aatcagcaag agtagaccat
    32101 tttataagga ctttaccaca agggtatgac actatattga ctgaggatgc ttctaatcta
    32161 tctcaaggtc aaaagcaact tctaacaatt gccagggcaa tactttcaga cccatcagta
    32221 ttgattcttg atgaagcaac atctagtgta gatactagaa cagaggtaga aattcaaaag
    32281 gcaatgaata acttgatgaa gggaagaact agttttgtta ttgcacatag attatcaact
    32341 attcgagatg ctgatttaat attagtaatg aaagaaggca ctattattga acaaggaagc
    32401 cataaggaac ttattgaaaa gaaaggattc tatgaagaac tttataatag tcaattttca
    32461 agtgaatatg atgaagaagt tgtatgatta tcaagtttta ggcaactaaa tgattgataa
    32521 atattaagtt aaatatagta acatgtaagg ttatatggaa taagagtatt tctctatttc
    32581 atataacctt ttttatttat caaaataaga taaaattttc tttctaaatt agattgaaga
    32641 aagtatttat caatataaaa gtaaaataat cattattatt agtgaagtaa atattgtttg
    32701 ccacatatat gccataaaga tgcacttatt ttacggagat ttaacaaagt agtgtaaagt
    32761 atactctaaa tataaaataa atcaaataga gttaaataaa ttgagaggtg atataaatag
    32821 tgaataaaaa attgaactat agatttgaaa tgaagcacaa aataactgaa gcagatgtgt
    32881 tagctttaaa atcaagactc tatccaataa tgaagaaaga tgaaaatgca tctaaagatg
    32941 gaaaatatct tattaggagt ttatattttg atactcctga agataaagca cttttagata
    33001 aattaaatgg cgttgcaata agagaaaagt ttaggataag attttataat aataactgct
    33061 cttatataag gttagagaaa aaaatcaaac attacaacat gacatcaaag ctatcaacta
    33121 atttaaccaa aaaagaagta ataaatatac taaacaatga tattgaattt ctaaaagagt
    33181 cgacaaattg tttattaaga gaattttatt tgaaattaaa atgtgaaaga ttagaggcaa
    33241 aaagcatagt tgattacaat agagaagctt ttatttatcc agttggaaat gtaagagtta
    33301 caatcgatag tgatattaaa acttctgtaa attcgataga tttatttaat aaagatttgc
    33361 cgactgtttc ggtaattgat gagaatatga ctgtattgga ggttaaatat gatgaattta
    33421 taccagattt tataaaggat ttaattcaaa ttaataagac tacttctaca gcagtttcaa
    33481 agtatgcttc aagtagatta tatatttaag aataaaggct atgatttata taaagatata
    33541 cataaataag gttaaaaaac aaataggtta aaaataaata aaataaaaaa taaataagtt
    33601 aaaaatagga aggatgattt taattatgac atttaatgat atttttaaat caagttttat
    33661 agaaaacgta tcaggttttt catttgtgga cagtgcttta gcactaggtt cagctttttt
    33721 agtaggtttg tttatatata tggtctataa aaagacttat atgggaatta tgtattctcg
    33781 accattcaat gtgtcgcttg tagcacttac aatgcttaca acttttgtaa tattggcggt
    33841 tacttcaaat gtagttttat ccttaggtat ggttggtgct ttatctatag taagatttag
    33901 aacagcaatt aaagacccaa tggatttagt atttctattt tggtcattgg gttcaggtat
    33961 agttttagga gcaggtttga ttcccttagc tgtcatgggt tcaataatta tgggattgat
    34021 tctaatattc ttttcaaata aaacaatatc tgaaactcca tatatattga tggtaaattg
    34081 taataatgaa gattcagaag atatagcaac tgataaaatt aaaaaagtat ttactaaata
    34141 tcaaataaaa tcaaaaagtg ttacaccaga aaaaggaata gaattagtgt ttgaagtaag
    34201 aatgaaatat ggagagacaa gtcttataaa tgacttgagt caagtagatg gagttactaa
    34261 tgcagttctt gtaagctata atggtgacta tgtagcatag agaggagtaa tcttttatga
    34321 aagataaaaa atttaccctt cttatctcta ttatgattat atttttatgt gctgtagttg
    34381 gagtttatag tacatctagc aacaaaagtg ttgatttata tagtgatgta tatattgaaa
    34441 aatattttaa cagagacaag gttatggaag ttaatataga gatagatgaa agtgacttga
    34501 aggatatgaa tgaaaatgct ataaaagaag aatttaaggt tgcaaaagta actgtagatg
    34561 gagatacata tggaaacgta ggtataagaa ctaaaggaaa ttcaagtctt acatctgtag
    34621 caaatagtga tagtgataga tacagctata agattaattt tgataagtat aatactagtc
    34681 aaagtatgga agggcttact caattaaatc ttaataactg ttactctgac ccatcttata
    34741 tgagagagtt tttaacatat agtatttgcg aggaaatggg attagcgact ccagaatttg
    34801 catatgctaa agtctctata aatggcgaat atcatggttt gtatttggca gtagaaggat
    34861 taaaagagtc ttatcttgaa aataattttg gtaatgtaac tggagactta tataagtcag
    34921 atgaaggaag ctcgttgcaa tataaaggag atgacccaga aagttactca aacttaatcg
    34981 ttgaaagtga taaaaagaca gctgattggt ctaaaattac aaaactatta aaatctttgg
    35041 atacaggtga agatattgaa aaatatcttg atgtagattc tgtccttaaa aatatagcaa
    35101 taaatacagc tttattaaac cttgatagct atcaaggcag ttttgcccat aactattatt
    35161 tatatgagca agatggagta ttttctatgt taccatggga ttttaatatg tcatttggtg
    35221 gatttagtgg ttttggtgga ggtagtcaat ctatagcaat tgatgaacct acgacaggta
    35281 atttagaaga cagacctctc atatcctcgt tattaaaaaa tgagacacac aaaacaaaat
    35341 accataaata tctggaagag atagtaacaa aatacctaga ttcagactat ttagagaata
    35401 tgacaacaaa attgcatgac atgatagcat catatgtaaa agaagaccca acagcatttt
    35461 atacttatga agaatttgaa aaaaatataa catcttcaat tgaagattct agtgataata
    35521 agggatttgg taataaaggg tttgacaaca ataactctaa taacagtgat tctaataata
    35581 attctaatag tgaaaataag cgctctggaa atcaaagtga taaaaaagaa gttaatgctg
    35641 aattaacatc aagcgtagtc aaaactaata cagataatga aactgaaaat aaaactacaa
    35701 atgatagcga aagtaagaat aatacagata aagataaaag tggaaatgat aataatcaaa
    35761 agctagaagg tcctaggggt aaaggaggta agtcaatacc aggggttttg gaagttgcag
    35821 aagatatgag taaaactata aaatctcaat taagtggaga aacttcttcg acaaagcaaa
    35881 actctggtga tgaaagttca agtggaatta aaggtagtga aaagtttgat gaggatatga
    35941 gtggtatgcc agaaccacct gagggaatgg atggtaaaat gccaccagga atgggtaata
    36001 tggataaggg agatatgaat ggtaaaaatg gcaatatgaa tatggataga aatcaagata
    36061 atccaagaga agctggaggt tttggcaata gaggaggagg ctctgtgagt aaaacaacaa
    36121 catacttcaa attaatttta ggtggagctt caatgataat aatgtcgatt atgttagtag
    36181 gtgtatcaag ggtaaagaga agaagattta taaagtcaaa ataagattaa aattgaatat
    36241 aaataatttt aatactgtta agtctaaata tttacttagc agtatttttt tagaaaataa
    36301 tgtgtttgat taataatata aggtaataaa ttgataaaaa ttaaatacag catattaata
    36361 atacataata aagtaataaa aaaactgttt aagtataata acttatattt agacagtttt
    36421 tttcatttat aaataatata aatgaaattg aaaacatttg aaggatagaa attggttgga
    36481 taaatgtata aattacttca ccaaaaaata atgacaagag ttgtaactaa gttgtaataa
    36541 aatggtagtt atttagcata aaataatgta tcatagaagt atattataaa attaataaaa
    36601 taagattttt gtaagaaaac tgctggcttt tgatatttag agtgagtagt taaattatgt
    36661 ttaggagggg tagaatttgt tgcaaaaagt attatggaaa tttttaaagc tagtagtcgg
    36721 tttatttata tgttcagttg gtatagtatt gacgataaat tgtaaccttg gattatctcc
    36781 ctgggatgta tttcatcaag gactttcaaa tcatatagga ataactatag gaactgcttc
    36841 tataattgta ggctctatag tagttattgc tgatgtcgtt cttggagaaa atgtaggatg
    36901 gggaactgtt tttaacatgc tactaattgg attctttatg gatttacttt tatatagtaa
    36961 tttaattcca gaggctgata gtttatttgt aggaataatt atgttgatat taggattggt
    37021 tcttttgtct gttggaatgg tattttatat gggaagtggt ttaggaagtg gacctagaga
    37081 tggtttgatg gttgcaattc aaaagaaaac aggaaaatca cttaaattaa taagaggtac
    37141 tatagaagtt ggagcattaa tagtaggatt tttattaggt ggaaaagttg gtataggaac
    37201 tataataagt gcatttggat tggggtattt cacacaaatg gtatttggct tatttaaatt
    37261 agattgtagt aagattaaac atagatttat agtagatgat ataaaattta tcaaagtgta
    37321 tatgagtggt gagaaaaaag ctgctgttca aaatatagtt aagtaattta agaataaatt
    37381 caacgaaatg ttaagtattt taaattaaca ttttatttag atggataaat tgaatattaa
    37441 aagaatatta aaatatgagg attgctagaa cactataaaa tatagatttc tagcaatttt
    37501 ttatttgttc aatgtttttt tagtactaga agtcttattc tctatttaat gaatgaatta
    37561 atttataatt agagatacta aactttatag atattaatat aaacaccttt aaactgtgta
    37621 ttttccaaag cctttaaaat gcttgtattt attctaaata aaaaaataaa aaaatgtcaa
    37681 aaaaactctt gtattatatc caaattttat atataattac ctatgttgtt tagaaatttt
    37741 aaactcaatg tttagtaaac aaaatgttta gtaaaataaa acagaaacta ggaggtgcaa
    37801 catggatata ggtgaaaaga taaaaagatt aagaacagaa aaacaactga cccaggaaga
    37861 gctagctaat agatgtgaat tgtcaaaggg atttatttct caattagaaa ataacttaac
    37921 atcaccatcc atagctaccc ttatagatat acttgaaata ctaggtacaa atttaaggga
    37981 attttttaat gaaatagatg atgaaagaat cagttttaca aaagaagata tgtttgaaac
    38041 tgaagatgaa gatttaaaat ataaattaaa gtggttaatt ccaaattcac aaaaaaatga
    38101 aatggagcca ataataataa cattgtatcc aggaggacag tataaagaag aaaagccaca
    38161 tgaaggtgaa gaatttggat atgtattagc aggttcaata tatgtccata taggcgaaaa
    38221 gaaaaataaa gtaaaaaaag gagagagttt ttactttaga ccaaaagcaa atcactatat
    38281 atcaaacgaa ggcaaaacta cagcaaaagt gatttgggta agtacgccac catcatttta
    38341 gaatagaggt gtttaataat tggtagaaaa tataatagaa ttaagggata tatctaaaca
    38401 ttatgaggaa cttactgttt tagataattt caatttagat ataaagaaaa atgagttttt
    38461 aacattactt ggaccaagtg gatgtggaaa aactacaaca ttaaaaataa tagcaggatt
    38521 tgagtatgct gatgatggta aagttttatt tgaaggtaag gagataaata acttgccacc
    38581 atatgaaaga caagtaaaca cagtatttca aaaatatgct ttatttccac acatggatgt
    38641 ttatgaaaat gtagcttttg gattaaaaat taaaaagact ccaaaagatg taatagatgc
    38701 taaagtaaaa gaggttttga aacttgttgc actagaaggt tttgaaagac gacaagttga
    38761 atcattgagt ggaggacaac aacagagaat tgcaatagca agagctctag tcaatgaacc
    38821 aaaggtatta ttactagatg aaccacttgg agcacttgat ttaaagttaa gacaagagat
    38881 gcaaatagaa ttaaagagaa tccaaaaaaa attaggaata acatttgttt ttgtaactca
    38941 tgaccaagaa gaggctctta ctatgtcaga tactattgtt gtaatgtata agggcaaaat
    39001 tcaacaaatg ggaacaccac aagatatata caatgaacct aaaaattcat ttgtagctaa
    39061 atttataggt gaaagtaaca tatttgatgg aattatgata gaagattata aagttaattt
    39121 ctgtaataga gattttgagt gtgttgataa aggattcgaa aaaaatgaaa atatagaagt
    39181 agtaataaga ccagaagata taaaaatggt aaagccagaa gaaggaatgt taaaggggaa
    39241 agttacatct acagtgttta aaggagtgca ttacgagata gaattgaatg aaaatggaag
    39301 attgtggata cttcataata ccaaaaatgc tgaggttggg actgaactag gcatggatat
    39361 atatccagaa gatatccata taatgagaaa agagaataac taagatgaaa agaaaatctt
    39421 ttttagcata tccatatgta gtttggagtg cgatatttgt aataattcct ttaatattag
    39481 tggtattttt tagttttaca aaagaatcag gtggaggtta tgcctttaca cttgagaatt
    39541 ataaagaagt aattgaccct atatatatga aagtttttgg gcgttctatt cttttagcag
    39601 gaggagctac attaatatgc cttatagttg gttatccagt ggcatatata atttcaaagg
    39661 ctcgtgtaag tagaagaggt tcattaatat tattgtttat tcttcctatg tggatgaact
    39721 ttcttttaag aacatatgca tgggttgcta tattaggaaa aaatggactt ttaaatacat
    39781 ttttaggttg gtttggaata caaccattag caattttgta tactaatttt gctatacttt
    39841 taggtatggt gtataacttt ttaccattta tggttcttcc aatatataca gcactatcaa
    39901 agatggataa tgatttgata aacgctgctc atgacttggg tgcaaataat atgacagttt
    39961 ttagaaaaat tatatttcct ttgagtttgc caggtgtaat gtctggaata actatggtat
    40021 ttatgccagc agtcactact tttgcaatat caagactgtt aggtggaggt aaaataatgc
    40081 tggttggaga tttgattgaa caacagttta cagttgttgg agattggaac tttggttcag
    40141 ctatatcgat atttatgatg atagtaatat taatatctat gtctataatg tcaaaatttg
    40201 gagatgaatc tgacaaagaa ggcggtgggt tactatttta aaattaaaga aaataacttc
    40261 taatatatat ttagcattag tattcttatt tttgtatgca cccatatttg ctttggtact
    40321 attttctttc aatgattcaa aatcaatggc aagatggaat ggatttacat ggaagtggta
    40381 tggtcaatta cttcaaaatg agagtataat gagtgcttta tattatacta ttgtaatagc
    40441 tatattagcg tctgtaatat ctacaatagt aggaactata agtgctatag gaatacataa
    40501 gatgagaggt aagagtaaga aattaatact aaatgtaaac tatcttccta ttttaaatac
    40561 agagatagtt acagcagtag ctcttatgag cctgtttgta tttgtaaaaa tggaatttgg
    40621 atttacaaca atgctattgg cacatataat gttttgtttg ccatacgtta tactttcagt
    40681 tttgccaaaa atgaagcaat tacctgataa tatagaagat gcagctatgg acttgggagc
    40741 aacacctata tacgctctta gaaaagtaat tttaccacaa ataaaaccag gtatagtttc
    40801 tggattttta attgcattta ctatgtcaat agatgacttt ataataagtt tctttaatgc
    40861 tggaaatggt gtaagcaatc tttctataga aatctatgga atggctagaa gaggtataaa
    40921 acctgaaata aatgcattat caacaataat gtttgcagtg gttctaggtt tacttttact
    40981 agctaataaa aaagaatcta tagtaagggg gattaaataa tgattaagtt taaaaaaaca
    41041 atatccctta tagctgtagg tatgatgaca gttactttat ttacaggatg taataaagca
    41101 actgattcta caaaagtttt aaatgtatat aatgttggag attatataga tgagtctctt
    41161 atagataagt ttgaaaaaga aacaggaata gatgttcaat attcaactta tgatactaat
    41221 gaaatgatgt atcaaaaagt aaagagtggt agtacacact atgatttagt atttccttca
    41281 gactatatgg tagagaaaat gaaaaatgaa ggtcttttgg aaaaattaga ttttaagaat
    41341 atacctaata tgaaatattt agataagagt tttttaaatc ctgtatacga caaaactaat
    41401 gaatatagtg ttgcatatat gtggggaact cttggaatat tgtacaataa gaaagaagtt
    41461 aaagacccta tggatagctg gaatatactt tggaatccaa agtataaggg aaatataatg
    41521 atgtttgact ctgttagaga tactataggg ataactctta aaaaattagg atatagcatg
    41581 aatagtgtaa atccaaaaga aataaatgaa gctaaaaatc ttttaatgaa acaaaaggat
    41641 ttagtattgg cttatgtaaa tgatgaaggt aaggatagat tgcttggtgg agaagtggca
    41701 atgggtatgc tgtattctgg agatgcagtt acgctaatgg agcaaaatcc tgaccttgat
    41761 tatgctatac ctaaagaggg aactaataaa tgggtagatg ctatgtgtgt acctacaaca
    41821 gcacaaaata agaaagaagc tgagctgttt ataaactttt tattagaccc agagaatgca
    41881 aaagtaaatg ctgagtacat tgggtattca acacctaata caggagcact aaaattatta
    41941 gacccagaaa taactcagaa tcctgttgca tatccatcta aagaagtact tgataaatgt
    42001 gaaacttttg aagatattgg tgaaaatata aaattatatg acaaggcttg gatagagtta
    42061 aaatcaaaat agggtcttgt tggtttaagt aaatttactt aataaatact taataaaact
    42121 gttctttttt agaaaattta ttttctaatt attgaacagt tttatttttt gtttaggtca
    42181 tgtttttatt ttgagtttat ttttatgaga atttaaagta cagtaagttt cattgattac
    42241 tatttttata ataataacta taaagaggtt gtctcgaaat tgagataagc ctctttttca
    42301 ttgttgaaat gatgaaaaca tgtttgattt cataaaaaaa gagtgattca tgagctaaag
    42361 aatttgcttt gagacagtat tttttattaa gttatattca tatgcaattt aaatagttta
    42421 ttaataaatg aaaacttatt tgtataatga ttttaataat aattagaaaa aatgggcaac
    42481 ttaatagaat aattggaggt gtaaatttat aaaaaatgaa taggataaat aaaaaaatag
    42541 atttattaat attggctttg ctcgttttta tatttttaat tgttggaata gtaatactat
    42601 cgattaggac agaaaataaa ttgaatgtgt tcataatgtt agcaataatt ttttttataa
    42661 taatgttaac ttatttatca aattcagtag tggggttgat aacaagttca ataattatat
    42721 ttatgtatac atcctatatt ttatataaca atattactca caatatggat gttgaattta
    42781 tatcatatat gtggataata gcaacaccag tatcttcaat tataatgggt aatctgaaca
    42841 aaagcataaa tgaattgcaa aatacaaata aaaaactatc tgaacagtat aaggaattag
    42901 tgactattga tagtgaaact ggacttagaa atttaaagat tttttataat gatgtaaata
    42961 tggagataag taaatctatt agacataata ctgatttttc tcttatgata gtaaaattac
    43021 catactacgg aaacctacag actatatttg gtgaaaacaa aactaataaa atagtaaaat
    43081 atattggttc aaatattata gaatgtacaa gaaatgaaga tataatttat agtttacaaa
    43141 aagatatgat agggatacta atgccaaata catctttgga aggttcgaaa gttgttaaag
    43201 acagaataaa gaaaaggata aaagaattaa atttagattt aaacaatagg ggaaaatatg
    43261 taaatataga tgtcaaaatt gcatttttac aatataagag tagttttgga gatagtataa
    43321 attttaagaa tatagttgaa gaggaacttc aatatgatgt ttaaaatatt taataaaagt
    43381 ttattaaaat tagtaattgt attatcaata gtactgacaa tatcaaattt tagcttattt
    43441 tcatatgcat cagaaattac ttccagcaca gataaggtat taatcatata tgattctaag
    43501 aaagaaacag cttataatag agatatttta aatattatga gaactctatt gggaagattt
    43561 agttcagata tagagctatt aaaattgagt aactatgatg gtgagataaa tgaaaattat
    43621 tacagtcata tatttatttt aggaatcaat gaaaactcat ataataatga taaaaacact
    43681 aaaaacttga ttagttcctt aaattcatat aaagtaacta tatgttggtt aggatatggt
    43741 atagaaaatc ttttggaaca taaaaaatac aatttagact atgtaggaaa aacaaacaat
    43801 atagttagtg taaattatag aggtaaatca tataacttgg atgaacatta tgtttttaac
    43861 attgtagaat caaaagatac aagtaataaa gtaataggaa gtattaatga taccttaaat
    43921 aagtatccat atataataaa tgataaaaat cttttttatg tatcaaaatt agatttagat
    43981 ggagttttat tttatatatt ttgcgattca cttaatgata tttttaatat taagacgttt
    44041 gataaaggac gtatatttgt aagaatagaa gatgtacatg cttttagaga accaaaaaat
    44101 cttgtagaga tagcggatta tttaagtagt aagaatatac catttacgat tgcattaata
    44161 ccagcatatg taaatcctaa aaatcataaa gtaataactt tatcagaaag ccctgaaatt
    44221 gtcaaagcaa taaaatatat gcaagataaa ggtggaactg tgatattgca tggatatact
    44281 catcaataca agaaagaaga agtttctgga gaagggtatg aattttggga tggtaaaaaa
    44341 gatgaaccct taaaagaaaa tatgaagata tttgtcaaag atagagtttt gaatggtctt
    44401 agagtatgta tagagaatgg aatttatcct cttgcatttg aagcgccaca ttatgcaatg
    44461 gaatcagagg gatataaaga attaaaaaaa tatttttcta cttatatggg gcaacatcaa
    44521 aataatgata aaaaatttag cacaaataca tatccttata ttattaggga tacagaggag
    44581 tttaatatat ttatacccga aaatttagga tatatagacc cagaagacaa gtttactttt
    44641 caaaatataa aagaaaattt agataaatta tctattgtaa gaggttttag tggagggttc
    44701 ttctttcatt catatttaaa catagagtat ctaaaaaaca caatagaata tttagaaaaa
    44761 cagaatatag aatttatgaa tttaagagat tttaataatt gggtaaaagt tgatgaaata
    44821 caaataagaa ataatggaga tgaaattata gtcaactatg ataaggactt agatgaaata
    44881 actaaaagtg atactagatt taaatacata tccaatatta gtaaaatttt aatattcata
    44941 gtatctataa gtgttttaat atttgtgatt atatttatat attttaagag aatagataaa
    45001 aagaaatttt taaaataaat gattttatat tagaatcaat attttaaaat attttaggag
    45061 aaatttatga gagatttaaa tgtatcagag tatttgttcg tatttagtct gtttagtata
    45121 tggtctttat tgcttataaa tattatttta gctatgggtg gatatatatt ttattttaaa
    45181 aactttgata aagaaataaa agaaattgat gaatatccta tgatatcaat acttgttcct
    45241 gctcataatg aagctaaagt gataggtaga actgtggagt ctttgttatt actcaattat
    45301 cctaagagta agatggaact tattgttata aatgacaatt cttctgataa tagtaaagaa
    45361 attttagaaa atataaagga taggtacaac aattataatt tcactataat aaatacagat
    45421 agtttaacag gtggaaaagg aaagtctaat gcattaaata ttggatataa ggtttcaaaa
    45481 ggagatttta tagctgttta tgatgcagat aacacaccag ataaaaatgc acttagatat
    45541 ctagtacaaa ctatagtaat gaatgatgaa ttaggtgctg ttattgggaa atttaggact
    45601 cgaaataaaa ataaaaacct attaaccaaa tttataaaca tagaaacatt aagctttcaa
    45661 tggatgtcac aagctggtag atggcaactt tttaatctat gtacaatacc aggaactaac
    45721 tttatattga ggagaagtat catagaagaa attgaaggat gggatagtaa agcaattgca
    45781 gaagatacag aaataagttt taggatatat aaattgggat acaagataaa gcttgtacca
    45841 caatctataa catgggaaca agagccagaa actgttaagg tgtggataaa gcaacgtact
    45901 agatgggcaa aagggaatat atatgtatta atgaaatata taaaaaatat atttaaacag
    45961 ggaagaaata agattgtgtt tgatatagct tacttttttt ctgtatattt tctattttta
    46021 acaactgtaa ttatatccga tattttatgt gttttaagta tatctaaact agtagaaatt
    46081 tctattccaa ttaacttttt tctaatatgg atactatctt atcttttatt tattatagaa
    46141 gtgagtataa gccttactat agaaaaaggt gaagcaacaa ttgaaaatat attcatagtt
    46201 gcaataatgt attttacata ctctcaacta tggctgtttg tagctataaa agggatgata
    46261 gagtatctaa aagatataat ttttaaaaga gaggttaaat ggtataaaac agaaagattt
    46321 tgattcatgt acaggaggaa ttaacatgaa aaaatttatt atatcaatta tatctttagt
    46381 attgtttttt tcaaatatat cacttatata caaagtaaat gctgatgaga ctaaagttaa
    46441 aaattataag tttgaaagag atataactat tgatggtgtt ataggaagta atagtacttt
    46501 ttttgaagta aataaaaatt gggatattga agaagtttta ttgcatctta attttagtaa
    46561 gagccaaata ttaaatggag atgtttcaag tttaactgta ttgataaata atgtaccaat
    46621 aaaatctatt aaattaaatg ctaagacaaa ttataaaaat acattagaag tattagttcc
    46681 aaaagattat ataattcaag gatataatga aataaaaata aaaacataca aaacaatatc
    46741 tgataaaatt tgccaagatg attccaatac tgggaactgg atggttattc acaaagaatc
    46801 atatatatca attagatata agcagaaaaa ggtggaaaac tcaataaatg aatatccgta
    46861 tccatatgca gaaattgaaa ataatcataa attagataca actatagtag taccagataa
    46921 tatgactaga ggagagacta cagcagtgtt taatttggca tcatcatttg gaaaaataac
    46981 aaaaaatgat gatttaaagt tagatgttaa attatattca gaaatgaaaa attggtcaga
    47041 tgataatatt atatatattg gtaaacctga aaatacagca gaagaaattt tggatatttt
    47101 aagtataaag gaacaaaccc tattatcttc aaactgtata atcaagcaag tagattcacc
    47161 atacaataag aataagaaga tgatggtggt aattggtagt aatgaagatg atttaataaa
    47221 ggcatcaaat ttattaatag aaaatagact ttctaaccaa gttttatcat catcagtgct
    47281 tgtaaacaaa gagactaata taaaaattaa tagggaacaa aaattaaatt taggtcattt
    47341 aacattaaaa gacttaggat attctgactt tttgttggaa ggagcattta atcaacaagc
    47401 tttgtttgat gtcaaaatac caacgggtaa ggtattagat gatggttcaa agattatctt
    47461 aaatttaaga tattctgaca atttagattt tgaaaaatct ttagttacag tgtctataaa
    47521 tgatgttatt gtgggaagta aaaaattgga taggtcacat tctaataatg ataagttaga
    47581 attaaaaata cctaaagata tagataataa aaactattat caagttaaat tgacatttaa
    47641 tttgagtata aaaaattcga attgtgttac tagagagagt aataatcctt gggcatatgt
    47701 atcaaataat tcttatttgg cgttatctac gaaagaaaat gaaaccttat cttttgaaaa
    47761 ttatccgtat ccatttgtta gagatgatga gtttaatgat ttaactgtga taatgccaga
    47821 ttattcaggg tcacaagcta tgacctggat gtttagatta ggtgttactt taggtacgaa
    47881 tataaattca cataatggaa atataaatgt aattagagga aaagaattta gtgacaagta
    47941 taaggatact aatattgtag tttttggagt gccacataat aattctgtta taaagatgtt
    48001 aaataataat ttaaatataa agttcgataa aaattactcc aattttatat caaatgataa
    48061 gataagcttt attgatgatt atggaaaaaa tatttctacc attcaattaa taaaatcacc
    48121 atataataat caaaaaaata tcatggtaat tagttcaatg aatgaaaaaa acttatattt
    48181 aggaatggat tatttgttga ataaaagtaa agttaatgat ttaaaaggag atacattgat
    48241 aattgatgaa tacggagagg tagaagattt agcttataat ttaaaaccta agaaagaagt
    48301 aaaagattca agctggaata tgagtataaa taagacaact aaagtatttt taatgatttc
    48361 ttttattact ataattgtag tcatgatatt atcaatgcta tatataaaaa aatataaaag
    48421 aagataatat gataaattta ttattttaaa agaggtatat aatttgagga aatatatgaa
    48481 taaatttaaa ttaaaaagaa gcattttaat ctcattaata atcttaattt ttatatttat
    48541 agtgtacttt gtaagtattg agttaaaaga tgggagtcta gtaaataatc aatataaagg
    48601 taagattaaa tcggccaatt tatctgtaga ttatgaaata aatcaagtta tgaaggatat
    48661 agataaattg ggattgaata cagtaaatgt acctataatt ataaatgtag agtccattaa
    48721 ttctgatatt atgtcaatag ataataatag taaagaaaag gcaattaagt taataaaaaa
    48781 attaaataaa aaaggtattt caacaatatt agaggcatat ccatgggttg aaaatggaaa
    48841 attgtatgag actgactgga accctataaa taaaaaaaga tttttttata cttggcaaaa
    48901 tgccatatta aatgaactta taattgatgt agcaaatcca ctggatgtaa atgttttaaa
    48961 tattggttct aattttgtac atttggaaga atatcaacaa aattggggtg aaataataga
    49021 ttttgtacaa tccaaatttg atggtcttgt aacgtacaga actaattggt ggtatacaaa
    49081 aaaagatgat tcaagtagta agttgtttta tgaacaaaaa ttgaacaata atttttttga
    49141 taagttagat tttatatcta tagcagcata ttttgagtta agtaataaac ctgttaatac
    49201 agtggatgaa ttaatttctg ccttacactc atctactgta aacaatagag gacaaaatat
    49261 aaaacaagaa atatataacc tttataaagc tcatagaaaa cctatatttt ttggagaatt
    49321 aggtttttca aatagagaaa gtgcaagttc tcagccgtgg aatcatactc cttcaaaagc
    49381 tgtaaatggc gaagaacaag caaggtgttt tgaggcatat aagaaagttt ttgaaaatga
    49441 agactggata aatggttttt ctgtgttttg tgtaggtaaa atagatgacg aaaaaaattt
    49501 ttacccatca aaagagagta taaaagttat taagtcttgg tatgaataat tttaaaagtg
    49561 tagaatttat atagattaaa tagatgatta ggagagatat aaatgaatga catcaaggtt
    49621 atgactgtat ttggaactag acctgaagct atcaaagtag cacctttaat aaaggaactt
    49681 gaaaaaagag agaatataaa aagtattgtt tgcgttacag ctcaacatag agaaatgctt
    49741 gaccaagtta tagaaacctt caatataaat gtagactatg atttggatat aatggaaaaa
    49801 ggacaaagcc tgaatgatat aacatgtaag attttaaata aacttccctt gattttaaac
    49861 aaggaaaatc caaatataat attggtacat ggagatacaa ccacaactct agctacaagt
    49921 ttgactgcat tttataataa agctcttgtt ggtcatatag aagctgggct tagaacctat
    49981 gataaatatt ctccttttcc agaggagtta aatagacaac ttacaggtat tattgctgat
    50041 atgcactttg ctcctactaa tttggctaga aaaaacttga tttctgaagg aaaacctaat
    50101 aataatatat ttgtaactgg taatactgct attgatgctt taaagatgac aataaaagaa
    50161 aactataatc atcctataat tgatgagatt ggtaacgata ggatgatttt gttaacctct
    50221 cacagaagag aaaatttggg taaacctatg aaaaatatat tcagagctat aaagcgaata
    50281 gtagatgatt ttgaagatgt acagatagta tatcccatac atttaaatcc taaaatacga
    50341 actatagctg atgagatatt tggaaaattt cctgaaaaaa ttcatattat agagccttta
    50401 gatgtagctg attttcataa ctttttaaat aaatcttata tgataatgac tgatagtgga
    50461 ggaatacagg aagaagctcc atcattaggt aagccagtcc ttgtgttgcg tgataaaaca
    50521 gaaagaacag aaggaattga agcaaagaca cttaaattag taggtactaa tgaagataga
    50581 atatataatt cagtgagcga tttattaata aataaagata gctatgttca gatgagtaaa
    50641 gcatctaatc catatggaga tggaaatgca agcaaatata tagtggatat aataattaaa
    50701 aaatttaatt gcaaatattt aaattagata aggtctaaaa cattaactaa ttgatataag
    50761 atttatgata atattaagga atacaatttt taagggggag taatatggct agaaaattaa
    50821 taaaaaattt aggtaaaagt aaaagtgtaa agagagtgaa acttttattt aagaagattt
    50881 ttattactgt attcatagta gcaagtatag ttgctatttt taatataacg aaatattttg
    50941 aggaattata caaagtaagg gatttaaaaa gtactaaaat tgaatactat atggatgtgg
    51001 ctgatgaagc aggagatgga aaggtccaat taagttggaa ggccttactt gctatagaca
    51061 tggtaataca tgatgaagat ttaagtaata taaaaaagaa agacacattg gatatagggg
    51121 aaaagtttat agtagaagat aaaaatgata aaggcgaaaa ggtgtataag gtaaaaaagt
    51181 ttaataaggt attaagcgaa ttgaaatttg actcttctca aaaaagtaga gcaagaaaat
    51241 acatgaaaga tttggaatac acataccttg gaaataaaca attagatagt agtgatgaaa
    51301 aaattaaatt tataaagaag ttagaagact cagctataag agaatatatt gattatggaa
    51361 tattgccctc tgtaacaatt ggacaagcta tattagaatc tggctgggga aattctaaac
    51421 ttacaaaaca gagtaataat ttatttggta taaaagcaga taaagcatgg aaaggaaaaa
    51481 gtgtagaaat ttcaacttca gagcattata atgaaaaaat tgtagctagt tttaggtcgt
    51541 ataattcatt acaagattct gtcaaagacc acagtttatt tttaattaat aataaaagat
    51601 atagaaaaca tgggttgttt gaggcaaaag attatattag tcaagctcaa gcattagaaa
    51661 atgcaggata tagtacagca gaagataaaa aaggaaatcg tatatatgca gagctattaa
    51721 tagatattat taggagttat aatttgcaat tgatagacaa taaagttgag acaaaataat
    51781 tgttaacttt atatgaggag ataacaagat aagattcttt tctacaaaaa gaatagaaaa
    51841 attgtaaaaa aaactaaaaa aatgtattga cttgttattt aaaaggtgat attattatta
    51901 ctgtactcga aagagaacaa aa
//
LOCUS       DAEQJM010000024        49742 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.024, whole genome shotgun sequence.
ACCESSION   DAEQJM010000024 DAEQJM010000000
VERSION     DAEQJM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49742
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.024"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            318..656
                     /locus_tag="KRQ43_001722"
     CDS             318..656
                     /locus_tag="KRQ43_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2742080.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            678..995
                     /locus_tag="KRQ43_001723"
     CDS             678..995
                     /locus_tag="KRQ43_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2742081.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1145..1822
                     /locus_tag="KRQ43_001724"
     CDS             1145..1822
                     /locus_tag="KRQ43_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742082.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2150..2917)
                     /locus_tag="KRQ43_001725"
     CDS             complement(2150..2917)
                     /locus_tag="KRQ43_001725"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBH2742083.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKVAVMPQNERDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            3723..4355
                     /locus_tag="KRQ43_001726"
     CDS             3723..4355
                     /locus_tag="KRQ43_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH2742084.1"
                     /translation="MTIPNSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVSPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(4726..5595)
                     /locus_tag="KRQ43_001727"
     CDS             complement(4726..5595)
                     /locus_tag="KRQ43_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH2742085.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(5692..6549)
                     /locus_tag="KRQ43_001728"
     CDS             complement(5692..6549)
                     /locus_tag="KRQ43_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2742086.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            complement(6764..8782)
                     /locus_tag="KRQ43_001729"
     CDS             complement(6764..8782)
                     /locus_tag="KRQ43_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH2742087.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLIMERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            complement(9053..9829)
                     /locus_tag="KRQ43_001730"
     CDS             complement(9053..9829)
                     /locus_tag="KRQ43_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH2742088.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGLIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(9886..10857)
                     /gene="asrC"
                     /locus_tag="KRQ43_001731"
     CDS             complement(9886..10857)
                     /gene="asrC"
                     /locus_tag="KRQ43_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HBH2742089.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            complement(10870..11661)
                     /gene="asrB"
                     /locus_tag="KRQ43_001732"
     CDS             complement(10870..11661)
                     /gene="asrB"
                     /locus_tag="KRQ43_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HBH2742090.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            complement(11662..12669)
                     /gene="asrA"
                     /locus_tag="KRQ43_001733"
     CDS             complement(11662..12669)
                     /gene="asrA"
                     /locus_tag="KRQ43_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HBH2742091.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEIIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            complement(13059..13748)
                     /locus_tag="KRQ43_001734"
     CDS             complement(13059..13748)
                     /locus_tag="KRQ43_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH2742092.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKAKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITFDSSKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(13811..14659)
                     /locus_tag="KRQ43_001735"
     CDS             complement(13811..14659)
                     /locus_tag="KRQ43_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH2742093.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            complement(14678..15565)
                     /locus_tag="KRQ43_001736"
     CDS             complement(14678..15565)
                     /locus_tag="KRQ43_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH2742094.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEVWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNINGSSFQELASTSSLIKKVAKIKNLNEKDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            complement(15623..16426)
                     /locus_tag="KRQ43_001737"
     CDS             complement(15623..16426)
                     /locus_tag="KRQ43_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742095.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDALYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACNECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            complement(16586..17038)
                     /locus_tag="KRQ43_001738"
     CDS             complement(16586..17038)
                     /locus_tag="KRQ43_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBH2742096.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            complement(17168..18670)
                     /locus_tag="KRQ43_001739"
     CDS             complement(17168..18670)
                     /locus_tag="KRQ43_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH2742097.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSVVLAGLTGIPVNVLIVV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFIGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            complement(18703..19569)
                     /locus_tag="KRQ43_001740"
     CDS             complement(18703..19569)
                     /locus_tag="KRQ43_001740"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBH2742098.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            complement(19654..20325)
                     /locus_tag="KRQ43_001741"
     CDS             complement(19654..20325)
                     /locus_tag="KRQ43_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBH2742099.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            complement(20598..21089)
                     /locus_tag="KRQ43_001742"
     CDS             complement(20598..21089)
                     /locus_tag="KRQ43_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH2742100.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            complement(21111..22475)
                     /locus_tag="KRQ43_001743"
     CDS             complement(21111..22475)
                     /locus_tag="KRQ43_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH2742101.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            22894..24069
                     /locus_tag="KRQ43_001744"
     CDS             22894..24069
                     /locus_tag="KRQ43_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH2742102.1"
                     /translation="MNLEKIKKFFGFPLDKKHKENVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFATPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCDETDAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIEKAITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            complement(24242..25639)
                     /gene="asnS"
                     /locus_tag="KRQ43_001745"
     CDS             complement(24242..25639)
                     /gene="asnS"
                     /locus_tag="KRQ43_001745"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBH2742103.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     misc_binding    complement(25716..25949)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(26118..26312)
                     /locus_tag="KRQ43_001746"
     CDS             complement(26118..26312)
                     /locus_tag="KRQ43_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HBH2742104.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     gene            complement(26586..28259)
                     /locus_tag="KRQ43_001747"
     CDS             complement(26586..28259)
                     /locus_tag="KRQ43_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH2742105.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPVDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSQLNIAINRND
                     GSLSQDNIGTGTLVSGILAGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     ISGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            complement(28269..31667)
                     /locus_tag="KRQ43_001748"
     CDS             complement(28269..31667)
                     /locus_tag="KRQ43_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH2742106.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNTLLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVVTVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIISFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSSINQDLETEDIGYRSINKSFKDEENRYKFIDGYNIQI
                     HNDLENEIYISKNASRQSGILSGIDVVHTPEFEEELAGLGMSQNFFKISDSLGVLSIN
                     NTDYSSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICSGLGNVNSEYAGIAEDSELIIIKLGKIDGFYNS
                     AMLFAASQYAYKKAFELRRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPHVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITVGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            complement(31833..33029)
                     /locus_tag="KRQ43_001749"
     CDS             complement(31833..33029)
                     /locus_tag="KRQ43_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBH2742107.1"
                     /translation="MFIEFFYLLRSRGLNISLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMLSR"
     gene            complement(33050..33871)
                     /locus_tag="KRQ43_001750"
     CDS             complement(33050..33871)
                     /locus_tag="KRQ43_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBH2742108.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            34335..35429
                     /locus_tag="KRQ43_001751"
     CDS             34335..35429
                     /locus_tag="KRQ43_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH2742109.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
     gene            35580..35936
                     /locus_tag="KRQ43_001752"
     CDS             35580..35936
                     /locus_tag="KRQ43_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742110.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(36029..37297)
                     /gene="eam"
                     /locus_tag="KRQ43_001753"
     CDS             complement(36029..37297)
                     /gene="eam"
                     /locus_tag="KRQ43_001753"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HBH2742111.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(37699..39081)
                     /locus_tag="KRQ43_001754"
     CDS             complement(37699..39081)
                     /locus_tag="KRQ43_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH2742112.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            39206..39892
                     /locus_tag="KRQ43_001755"
     CDS             39206..39892
                     /locus_tag="KRQ43_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HBH2742113.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEGVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            complement(40078..41613)
                     /locus_tag="KRQ43_001756"
     CDS             complement(40078..41613)
                     /locus_tag="KRQ43_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742114.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFNLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            41888..42937
                     /locus_tag="KRQ43_001757"
     CDS             41888..42937
                     /locus_tag="KRQ43_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2742115.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENRVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            complement(42986..44020)
                     /locus_tag="KRQ43_001758"
     CDS             complement(42986..44020)
                     /locus_tag="KRQ43_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742116.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVVWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(44038..44385)
                     /locus_tag="KRQ43_001759"
     CDS             complement(44038..44385)
                     /locus_tag="KRQ43_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH2742117.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            44643..46025
                     /locus_tag="KRQ43_001760"
     CDS             44643..46025
                     /locus_tag="KRQ43_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH2742118.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            complement(46106..47899)
                     /locus_tag="KRQ43_001761"
     CDS             complement(46106..47899)
                     /locus_tag="KRQ43_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH2742119.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDGIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILDELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(48152..49543)
                     /locus_tag="KRQ43_001762"
     CDS             complement(48152..49543)
                     /locus_tag="KRQ43_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH2742120.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
BASE COUNT        16548 a         8337 c         5456 g        19401 t
ORIGIN      
        1 tataaaatag aaaatttttt taattttcaa aatatattct acatatctaa tatgtaatta
       61 caataaaaaa tgctataatt aacatattat taattcgttt tattattgta gtatggctat
      121 gaaattatga aaatatttct ctaattaaaa atatgattta tccatatttg tttattgtag
      181 atacagacta tacaaaaata aatagcactt atttcagtat aaaaacatat atagtctata
      241 tttagactaa aaaagtataa atagtctata taaaacaact taaactatga atataatcta
      301 aagtggaggg ataataattg gcaaatatag gaaaaataat aggagataga ataaaagtct
      361 atagaacaaa attgggatat agtcaagagt ttctagcaga aaaggcaggt ttacatccaa
      421 catatattgg tcagattgaa agagctgaga caaatacatc tatcaatatt ataatgaaaa
      481 ttgctactgc tttagacata ccacttgaat tgttatttgc aaatattatt acaacagaag
      541 gcgttgataa ctctgtacct ttagaatgtt atgaaatgat taataaatta actgaaaaag
      601 aacaaattgc aatgctagag ttaataaagt gcatcattaa atacaaagaa atataagtga
      661 gggaaatagt aacaataatg aattatatag gtaaaagact taaagaagaa cgaaaaaaag
      721 caaatttaac ttcaaaagaa tttgcaaata tggttggagt atcgccttgg tatataactc
      781 aaatcgaaag tggtaaaaag aatccaagtc ttaaaacatt cataaaattt gtaaatatat
      841 taaatatttc tgcagatgtt cttataaaag atattacttc cactggaaaa acatatttag
      901 aaaatgatat aaatgaagag ttaaaagact taaattcaag agaactaaat ctgatatcac
      961 agattataga catcataaaa aagaataaaa tataattctt tatattttat ataaaaaaaa
     1021 aggttatttg aaataaataa cctttttttg tctttttgtg ttaacattgt cttatagtgc
     1081 taatgagtac tattagacca tgttctatgg ccttatttta atataaaacg attggagata
     1141 ggctatgatt gtgattgaag gtagtgataa atttaagatt gcaaaagaat atattgatgt
     1201 agaatatact ctttttagca aagtaacttt taggtatgaa aagttgaaat ttaaagataa
     1261 tgctgaattg gaaaaaatta agatgtttaa atataaaaat ggctacatcc ctaataaatt
     1321 aaacctttct tttggatatg gattctcttc ttataaaaag caaataatta gagaaactgt
     1381 agatacttta agattgacag aaattttttc aagcgagaac atagaagata ttaaatttat
     1441 aaaagatggt acaaaaaaat tagaaattag catagagaaa gttgtgaaat ttaaacgtcg
     1501 aaaaaaaaga aattatgttt gttgctattg ccctgatatg tatagagata taaaactcga
     1561 caaagaatct atcaataaga tatacaacag aaaaataaaa atagaaagag aagttaatat
     1621 ttttgaagat gaggatgtta taataaacaa gaaagtattg aagtttccaa agtcttggac
     1681 aaagaatatg caaaaatatt ggttaagtga aaataagtat cccatacatt ctactgtaat
     1741 tgatgatgat agatataaat gttgtaatgt acaatataca aaaaatagag tgataatatt
     1801 atattacata tataaccatt aatatacata attacaaaaa aataatgaca aatatacata
     1861 atacaaatat atcttctact ttagataaaa cagttattat gaaaacttac tatctataaa
     1921 taatagaaat gctagtatac catctataat ctaatgtcta gtaggtttta atggcatatt
     1981 ttaaatatgc catagttgat ttataagatt ttctatatca ctttcaaaat acacactaaa
     2041 tagttgcttt tcagatataa ttgcccaatt taaattttac tatctgaaaa gttttttata
     2101 tttaatttat atcttcaaaa ataccgtcta atatttctat ataattaatt taattaatac
     2161 tcttatgtaa tagattaagt actgaattta actctttaaa tgatatttgc cctggtgctg
     2221 aaacactttt tgcagctcca aaagtcaatg cagaaccaaa tatttcacca cacaatctac
     2281 ttataacacc cattcctgac attgacattg ttattattgg tctatctgca taaattttaa
     2341 acatttcatt tgtagcttca agtagcacta acacatctct ttcattttgc ggcataacag
     2401 ctactttggg taaatctgcg cccaattcct gcattctaca taaacgagat acaatctctt
     2461 ctttttttgg agttttatta aaatcatgat tagatataat tactttcact tcttttttat
     2521 gagcaaaatt aactacttca tctatgacct catctcccat aaataactct acatctatta
     2581 aatctactaa acctgtatta gaaatttctt tattcaaagt agtataataa tctcttgata
     2641 ttaatttttc tcccccttct actacacttc taaatgtgaa taataaaggg atatcatgta
     2701 tataacttct taattcatag agaacttcct taacttcttt aatattttct acattctcaa
     2761 aaaaatcaac tcgccactct ataatatcca aacatgcatc ttttaactct ttagcctctt
     2821 ttataatatc ttttttattt ttcccaataa ttggtacaca aattttaggt ctaccttctc
     2881 caatagtaat attttttact tgaacttttc ttttcatatt ctcctccata atcagaaatt
     2941 ctataggact ttaaattcta ttttctgcat aatttaatta tacattaaaa atactataca
     3001 ttataaaaat actaatttaa aaataatttt tattctaatt cttaaaacaa tcccacatat
     3061 tttagaaaag gtactctata atatacaaac acttcttttt tacctaaatt tattttaaca
     3121 ttctataatt ttcacaatat tctttaaatt ttactcatat aaacaatatt attctggatg
     3181 ctaatagaat taatctataa atcatagtat aattatgcag aaataactcg aatttcacta
     3241 cttataaaga gattgaatat taatgaatct aaatcatttg cattacttca gagttttgac
     3301 taaagttgaa caccatacaa aagtagctac tcaattgttt ataccccaac caagcttaag
     3361 taatgttata tagattcttg aaaaagaatt tggtatcttt ttatttgaaa aacaaggtag
     3421 aaatgtttcc ctcactaaat acggaagttt ttttctaacc tatgttgata aagcattagg
     3481 ttaattagaa aaagtttaca tataaaatat attaaattgt tgcaagtttt attgttttga
     3541 tatacaatca actaaacata taatctttat aaaatactat acagttaaaa gtctgtttta
     3601 aaaaaaaatg tataaattat aaatcaaaat atagatacta tcaaggagtg attctgtgaa
     3661 gagatgtatt gtagtagtgg aatagtcaaa aacataatat atattaaagg agagatttaa
     3721 atatgactat tccaaattca aataaggtat atccaagaag taatgattat caaactgtat
     3781 atcttaaaaa tgtaataaca agggaaaata tagaagttgg agattacaca atatataatg
     3841 acttttataa tgacccaaga gattttgaga aaaacaatgt attatatcat taccctataa
     3901 acaatgataa attaataatt ggtaagtttt gctcaatagc atgtaatgca aaatttctaa
     3961 tgactagtgg aaatcactca atgaaatcaa aatccacata tacttttccc atcttttatg
     4021 aagaatggaa actcgatatc aaccatataa cggacgcttg ggacaataag ggtaacatta
     4081 taattggaaa tgatgtgtgg ataggttatg attctataat tatgtcaggt gtaaatattg
     4141 gtgatggtgc aattattgga acaagagcag tagttactaa tgacgtctca ccgtattcta
     4201 ttgttggagg agtacctgca aaaattataa aaaagagatt taataatgat acaatttcaa
     4261 aattattaga aattaaatgg tgggattggc catataaaaa aattcaatca aacattaagc
     4321 atattcaatc aggaaatatt gataaattag tttaatattt tataatttat ttatattaaa
     4381 ctttacttta ataatccttt tataagagct ttttcaaaat ttgtatatta ttttaatata
     4441 tataaattta atacaacatt aaataaaata aaaagtaaag ttacttaata aaaagttact
     4501 ttacttttta ttatttaaat tcctgttttt attataatag gtaaaattct attaaactag
     4561 ttcacatttt cattattatt gatatattat atatgaatat accattttgt tttttaataa
     4621 aaaaatcatg ctacatcagt agtaagcaac tattaatgta gcatgatttt ttgtatctaa
     4681 ataatcttag tatttaccta tcaatataga ttgatatatc aaaaactata gtcttctata
     4741 ttcttctctt tttagctttt ggttacttag atagtaatca atttcatcaa ttagacgttg
     4801 tttatcatca ggtaatacac cttttaaatt agcataattt gatgcatgat tacttctaaa
     4861 tacaattttt tcattagcat ctatattctt tatcatctct ttaatttctt gtaacacagc
     4921 cttatcctct agtattgtaa actctcctgc cttaagtaaa tcgtaaagtt cagtattagg
     4981 ttctaccatt aaactaagta cacccacata atctggtgaa attgctccta acatttttcc
     5041 tgtatcaact gcatgctgat gtgttttttt agttcctcca agacctgcta ttacagtggc
     5101 tgataattta atcccacttt ttttaacttt tctaccaact tttattaatt gttcactact
     5161 aaaacctttc ttaatatctt ctaatacttc attgcttcca ctttcaagcc ctagataaat
     5221 cattttaaca ccaagttttc ttaattcttt aagttcatca tcagattttt tctctataga
     5281 tttaggagag ccgtacatag taattctttc acactctgga aaaacttctt ttatatataa
     5341 aataatatct cttaatttct ccattggtat tatcaatgca tctccatctg ctaagaatat
     5401 tctttctaca tgcttataat atcttctaaa tatatcaatt tcatttttta ttacttctag
     5461 tggctttatt ttaaattttt tagatttgta catactacaa aacgtacatt tgttatgaga
     5521 acatcctagt gtgacttgta ttataagact ataagcctca cttggtggtc tgtaaagtgg
     5581 catatcgtat tccatattaa aatccccctt gtaataaaat attcattcta ttatattatt
     5641 aatatttact ttaaataata acttataaaa ttatattttt taaattttag tttaagatat
     5701 attctttaaa aatttaatga tactattggc agtaatatta agttgttttt cttgacttat
     5761 aatagcatca ttatctccct tttgttttcc atagtctcca aattgtgcat gatttcctcc
     5821 ttcaatctca acataagttg tatcatcagg aagtttttgt tttgattcta caagactttt
     5881 aaaattgact actccatctt tgctccccca tatagatata actttttttc ctaattcttt
     5941 caactcatca cccattggat aagaagctaa aaatacaacg ccttcaatta atttattatc
     6001 acgtgcaaaa tttgatgctg caactcctcc taatgaatga cctcctatta cccaatgttc
     6061 tatgttgttg taagaatcca taactttctg tgccttatta gttccaagta tagctagatt
     6121 aagtggcatc tttacgatta caacctcata tccactttct gctatttttc ttgcaagtgg
     6181 agcataagat tctatttcta ctttagctcc tggatacaaa attaaacctt tagaaacttt
     6241 tcttcctttt ggtgtaaatg aaatgttttc atttacagtt acttcaactt tactattgct
     6301 gactagagct tcttttgcca gcttttgagg ttcatatgtt ttatttatcc atatgaaaaa
     6361 gccaagcaaa atcaatacaa atagtatacc tattccctta aatatcttat tctttatgtt
     6421 aaattttcta ttattatttt tatcatcttt gttctcaacc tcatcataaa gtaaaggtct
     6481 ctcaagttcc atagttatac taaatgtatc atatttctta ttacgcttta cctttacatc
     6541 tttactcata aatctaaccc ccataatatt tgaatactat tatagtttat cctaagtaaa
     6601 ttgttttttc aaccaatgaa aaaaatcaat attttaacta ttttcatata aaattcataa
     6661 atatatgttt tttgtttttt atatattatt ttcttttagt attttataaa acaaatagcc
     6721 atatacttta ttttaaatat atggctattc tataatttaa tatctaagct gcttctttta
     6781 ttgaaacttt agttatatta cttattctat acatttcttt gacaccattt agagtttgca
     6841 gtaagtttag acatattatc ttgtcaccta gacttttagt atttacaata ctctctaaaa
     6901 ttacacttct tccttcatca tacttatcta cattgtaatt tgaaatataa ttagtatctc
     6961 tcaatatttt ttcaacatct tcatctttta ttttattttt attaacattt atatatagat
     7021 tatacatatt acttattagt aatttctgat tttctaaaaa atcctcttga tgtttatctt
     7081 tatatatagc atttatcaac ataagtctat cttcaataag tgatggtatc aataataaat
     7141 tttttatata gtaaacatca gctacatttt ctatagactt attgacttca tcaattatat
     7201 ttttaactat tcctttatac atttctataa catgttgata gcctgtttta gcatcatatg
     7261 gtaatataaa cttatttact attaatgcaa taattgctcc taatgctaca tatgaaatcc
     7321 tgcttatggt taaaacattt gggtctccca taactactgc tgaaccaaga gctgaaacag
     7381 ttacacatac cattaatttt ctataatcaa ctacataaga gtttatatac cctgctaaaa
     7441 gaactattaa cgaccttaat gtactatctt ttattattga aaataataca ataaatatta
     7501 cagctcctat aaatgtacct tctattcttt ttctagacct ttgtatacaa ttttctgcgt
     7561 aaggttgtgt taatgaaaag acagttaaca ttatccatct tccatctctt aaatggaaat
     7621 aatccataat aaaacccgct acagctgtag ctaaagcaat ctttactgca taagaaaatc
     7681 ttatagaatt taaattaaag tttttcttat atattgatag tcgtttaaat tcatgaggta
     7741 tctttgattt tctttcagct ttcttttcgt ctcttgattt tactttttta taatctacta
     7801 aaaactcata taaattttct aaaacactat aaatttcttt taaatttata tttttagtat
     7861 cctgagcaat aacataatct ctaaatccta atatctcttt atcagttatg gtatctttat
     7921 tttctaaaca catcttaata tagtttattt ctttcgttgc tacaactaga acatctgatt
     7981 tactatttat gctactttct tctaaaatat tttttatatc ttcatcttca aattctttac
     8041 tatccttttt gtatctttcc atgattaaac ttattctttc taatgaaaat aaaatattca
     8101 ttatgtctat acctctaata ctgatataaa agtcatcttt tctattatca aaaataacca
     8161 ttttcaaatt tttagatata gaatttattc tataattaca gctatctatt tttctcatac
     8221 tagatttaat tatagaacta tcatcattaa tagtattttt taaaagacta attttttcta
     8281 ataattcatc acatatagat atcagttctt tatctccgac atttttcatc ctatttctat
     8341 tcataacaaa ttgagcaatc attattataa ctgctccaac agctaaagcc gacaatctca
     8401 taggaaattc actttttcct acaggtatac ttaccataaa tatatacatt agaccaaaag
     8461 gtacatatac tgctctcttt aagtcataac taaatacata ccctattata aataatgcta
     8521 taaaatttaa taaaactcct aaatacatat tttgtactgc aaaaaatgat agtattccta
     8581 agattatatt tattgctaaa tacttcagta aatttttaat tggagaaata gttaaatctc
     8641 tttccaagag tgttagcata gctgttacta tacctacacc tataagtgta tttttacttc
     8701 caaataaata tataaatata gaaataaatg ctattataaa aataaacaac tttgtttttg
     8761 atattactag tttctttgtc atcatatccc ccctaaaaat ttcaacaaga ccaattttat
     8821 catatttgtt atcttattca aaatgcgctt ttttacggta ggactttaac tttttttata
     8881 tttagaacta tataattcat atataaacgt atttttttta tatataaccg atatattttc
     8941 gtatgctccc atattttttt tgtttcaaat attttttcaa aaatataaaa ataactctct
     9001 caataatact aaaaatgtat ttatcaagag agttataatt tatacaataa atttaattaa
     9061 gcttttcttt acctaatata taagttccaa gacccataaa taaagctcct ccaacaatat
     9121 ttccaagtgt tacagctact aaattataaa tagctcctcc aatagtaact gtacttattg
     9181 ttggtgaaaa taatgaaaca ctataaattg tcatatttgc tacactatgc tcaaaacctg
     9241 atgttataaa agcaaataaa cataagaata tcataattat ttttgcagta tcactattag
     9301 ttctaaacga acacaacact gatacacata ctagaatatt acataaaatc cctctaaaga
     9361 aaagagctgt aaatggcatg gatgctttac tagctgctgt atttgcaaaa aattcagcta
     9421 caggtccttt gtctactaga ccagttccta caaatataag acctaaaacc aaagctccga
     9481 ttaaattacc tacccaactg tatgcccata ttttagaagt atcttttata cttacacctt
     9541 tatttaacat accagcagac ataaccatat tgtttccagt aaataactct gttcccgtca
     9601 ttataaccaa acttagtgct attgcaaatg ataaccccat tactatctta gtcataggtg
     9661 aacctgcatc agtcaaaagt cctcctatag taaatatcaa aagtatacct atacctacat
     9721 aaagtcctgc aaacgcagaa gataccaaat attttacttt acttgtgttt aataaattta
     9781 tcttatttat agctgcatta gttaatttat ccaaagtttc tttatgcata attccctctt
     9841 ccttctatta aattttaatt tattcaaata tatgttttac tcaatttata gatatttaat
     9901 tccactccag tatatgtttt cgtacatttt agttatttct ggaagctcta caccttcaag
     9961 tgcccatttt ttaaattcca taaatcctgt tctatcaatt atatatccta tatgttcttt
    10021 tcctcctggt gcatctttat ctatatactt ttctacatat ctataagtat taagtattat
    10081 ctttattatg ctgtcctcat ctacccataa aagaaaatct tctgctagtc tagggttttt
    10141 ctttcctgtt ctacccatta tagctaatct atagtatttt ttctcatctc tagtccatgc
    10201 atttgttggg caatttagta cacactctcc acatcctata cacttatctt tatctcttac
    10261 caccttatta ttttctgttt ttaatgctcc aacagatatt ttagaacatt tttttacaca
    10321 tgctccacaa tttacacatc tatctttttc atatattggt aaagccatac caataattcc
    10381 aaagtcattc attctagctt ttatacaatc atttggacaa ccagttaaag ccactttaaa
    10441 atgtaaatca tttggaaata tagctttttc tattctttta gcaaattcag ttgtattata
    10501 ttgagccttt ggacagactt tatttcctat acaagctgct atatttcttg tacctgctgc
    10561 tggataacct gcgtttttct cactttgatt tatattcatt ttttcaataa caggttgtat
    10621 aattttattt atttcttcca tatcttccat atttattcct aatatttcaa acccctgtct
    10681 tgtagttatg tgcacctgtc catttccgta ctcacttgca attttagaaa ctacagctaa
    10741 actctcaggg tcaataagac caccaggtac tctaactctt aaagaagtct catattttgt
    10801 ttttgtaatt ctataagcat ttttcattac ttttttggta tttaaatctc ttatcacaaa
    10861 cttcgccccc taatcaataa gatttttagc atatgaataa tcaaatactg gtccatctaa
    10921 acatatgtaa gtatcatcca ttttacaatg tccacattta cctattccac aacacatttt
    10981 tctttcataa gaaacccaaa tgttcttttc atctaaatct ctttttaaaa attcttctac
    11041 tgtaaatttc atcatcattg gaggtccaac tacaactata gaagtattgt ttatatcttt
    11101 catatccaat tctggtatgt attttgttac taatcctaca ttaccactat atccttcctc
    11161 tgctccatct acagtaacta aaatatcaag ttttttactc catctcttta aatcatctgc
    11221 aaataaaata tcttttggtg atttaaatcc tactattaat ttaaactttt cgcatttttc
    11281 tttattatta taaaaatatt caactattcc tcttacaggg gctaatgcac ttcctcctgc
    11341 cactactaca atttctcttc cttcataaag ggatacatca aatccatttc cataaggacc
    11401 tcttataaaa aaagaatctc cttctttata attaaacaac tcgctagtta cttttcctac
    11461 atttcttatt gtaaagtcaa tataatcctc tccatatcct gatactgata ttggactttc
    11521 accgtattta ggtatagata tctcataaaa ctttccaggc aatacacctt ttgtattgca
    11581 gtttactcta aaagtccatt ctttatcagt atgtttaact atatctagta tttttgcact
    11641 tactggtata tatgggttca tttatacttc ctccttacta attactaaat catttatttt
    11701 ttctatacac tttgaaaatg atatgtattg cggacaggca tcatcacatc ttccacaacc
    11761 aacacacata tgatatccga atcttttttt aaaatcatgt attttatgca tagttttaaa
    11821 tctcattctt tcaccttgtt tttttctaaa agaatttcca cctgctatat ctgtatatcc
    11881 atctacttga caagaagccc aaacccttct tctctcacct acattttcgt tttccttata
    11941 gaaaatatcc tgcattgtaa aacatgaaca tgttggacat acaaaattac atctaccaca
    12001 tcctatacat cttgtatcat attcatccca tattgaattt cctataattt catttgaatc
    12061 aatattctct ggcacatcta cagatattaa attatcagtt acataatcaa cattaaattc
    12121 agttgcttct ccattaaata cttcaaattc actatccttt atatctaagt acagtgtatc
    12181 tccttctata tttaatccaa ttgaataatt atcagttttg ttagaatcca tgctcacaca
    12241 aaaacagttt ctaaaacttt ccttacaccc tacaagtgca aactttactt tatctctgat
    12301 atttttataa aaataatctt tttcttcacc attatttaga tatatttcat caagtctttt
    12361 tataccattt atgtcacaag ctcttaagaa aattaaaatt ttcttgttgt ctaaatcgct
    12421 ttccttaaac tctttttcag taaaataaaa caatacttga tttatgggaa gtacaacttc
    12481 ttttggtgaa aagtttgctt tcttagcaaa ttccatttct tcaaaagcgt ttacctcctt
    12541 gtatcttata acatcagtat ctgaaaaagt acctttaaat gggattaaaa ctggtgcaaa
    12601 tatcttgtag tcttttttta gataattcag accttcattg aacttagatg aatctaattt
    12661 tagtttcatt tttatcacct ttcttatatt ttagttttac ttacttgcta tcttgtttaa
    12721 atcttaacac tttattttct atgcttctgt gataattatc acagtttcaa aaataataaa
    12781 aaaatattaa tagagtttac taatctctgt taatattttt ttattatcta tattattcga
    12841 tttcaaatct aatcacttag atacaatcat taaatacaat aaaactatta tctactcaat
    12901 tttttgaata ataaagaatc ttatttgctt ttttatacaa ttcaataggg taaaataaaa
    12961 attaataaat tagacaataa aaaagaatct ataaatagat tctcttaata atatttttat
    13021 ttaattaaaa ttctaataat acttttactt aatcataatt aattattttt gaaatacctt
    13081 gataattcag tttctttaac ataaaaacct ttattatcaa tcttaataag ttcttctttt
    13141 tgcaatacct ttatcattct ggaaacagtc tcccttttac agccaagcat atcagctaaa
    13201 tatgtaactg taatatttac atttagtaaa gtccattctc cacagcaaac tccaaattct
    13261 ctacttaacc tatataattt tgctgcaagt tttttatcta cttttatgga tatagaattt
    13321 ttcaactgtc tatataaacg tcttattctt ctttccatat aagaaataat atcctttgta
    13381 agttgaaaat cattttgcat aatttctaaa aattcttcaa tactataata agctacaatt
    13441 gaattttcaa atgcttcaca gccaacagtg gagtttttag aagagtcaaa tgtaatatca
    13501 tttatgactt ccccactatt taatatgaaa attacttttc tctctccatt ttcacttatc
    13561 ttaaaaatag atacctttcc ttctaaaagt atataaacac tgtctaagct atctttttca
    13621 taaaataaaa tttctttttt ttgtaatctt tttagtttag ctttttcttt aagttgattc
    13681 ttcgttttag tacttaaatt attaaaaatt attactttat caatattata atcttttaat
    13741 ttagacatgt aatatctctc cattcctaaa tttttaagag agctctataa aacattacaa
    13801 atttcttatt ttattcattt ttaaacaatt ttatagcatt tgtagtttta attttccttt
    13861 caatagcttc attagaaagt tcttttacta cctgtgtata tactaaatca ataatgaaaa
    13921 attgtgctaa tttagaagat attgaaccag tttccagtac tgtttctcct gatacataag
    13981 ataagtgtac atctgaaata tcctttaatt cagaattttt attttcagta attgatataa
    14041 ttttagcatt attggctctt gcaagcttta cagtttttat aatctcttct gtttcaccag
    14101 aatgtgaaat tgcaattatt aaatctcctt cttccattat ggaagacatc attatcatcg
    14161 tatgactgct atcaaaactt acacaattaa ggcctattct cataaattta tagtttgaat
    14221 cctgtgctat tataccagaa tatccaatgc ctatgaagta aactttcttt gcatttatta
    14281 taagccttgc acagtcatgt acatccttac tattgattat ctctactgtg ttctctaaag
    14341 tggttacatt tgaacttaaa agtttttttg ctgtatccaa agctggctca tcattttgta
    14401 tatttttatt tataatattt tttttattga tagttgatat ttcttgtgct aaagtaactt
    14461 taaaatcctg taatccatta aaattcattt tttttacaaa cctagttata gttgcttcac
    14521 caatattgct ctctttagct atttgtgata ttggtttata aaatacatca tctatatttt
    14581 cttttatata agctattaat aatttatctg attttgtgac tttaaaagtt ggtgattcca
    14641 attgttctaa aatactcatt aaaaaccctt ctattcttta tattttgttt aaaaaattat
    14701 ataatgctcc aagcattcct gcatcatttt gtctctttgc aaattctata ttagtgtttt
    14761 tgtaaactct ctctataaga acctccttta atgctttgtc tatttttggt tttaggaact
    14821 tttcttgtgc cataatccca ccacctaaaa ttaccacttc tggatttatt acataacata
    14881 tatttgcgat tccaactgct aatgatttta tcatattatc gagttctttt aaacaatctt
    14941 catcattatt ctttgctaaa tcaaaaatta tttttccatt taagtccttt tcattcaaat
    15001 tttttatttt tgctactttt ttaattagac tgctagtaga tgccaattct tgaaaagaac
    15061 ttccatttat attcatatat cctacttcac cagcgctatt actaaaccca tttatcagtt
    15121 tattgtttat tataatacat ccaccaattc cagtacctat tgttaaacat atagaagatg
    15181 ttgcacctct acctgcgcca agccacactt caccaagtcc agcacaatta acatcatttt
    15241 caacttcaca ttttatatta aactcttttt ctacttcttt ttttaattgc atacccttat
    15301 aatttggaat taattcttct aatgcaaata gtattttacc ttcaactggg tcaaccatac
    15361 ctgcagttga tatacatata ccacttattt cattttcctc tatatatttt tttactatat
    15421 cttttatttt ggctaatatt ccttctccac ctttttcctt tgcttcagta tcaagacttg
    15481 atttatcaat tataaatcca tcttctctaa taaaaccata ttttattgaa gtacctccaa
    15541 catctataca aacgtaattt ttcataacat atctccatac aaattatttt tataaattaa
    15601 caactctatt taaaatttta tattacacaa atcttttact tatcttttcc aattcacaga
    15661 tatatttcct tgcttctgat aagtctatag tatcacttaa tacacttttt tctttggtta
    15721 tatgatactt ataaatattt ttacataagt cctctcctaa catattaaga ccttcttgag
    15781 tgtaatgaac atcatcaata gttaatcctc tgtcatgaaa ttgcatagca attttacttc
    15841 ctacacacag tatatcacat tcattacaag cagattcttg agctgctgca attcgtcttg
    15901 ttctaataaa atattcatct tctccaagcc aataaccagt taaacttaca aacattttat
    15961 caatcataca ttcttcttta agcctatacg caattttttt tagactttct ttatagtaca
    16021 atgcatcact accatatttt gcatcacttt caccttgaat ccaaataacg tatttatttt
    16081 ctatattata atgtttactt aaggtagtac agcctgtatt aaatttttct atagtgtcat
    16141 ttagaaacca gttattatca tgattccagt tttttattct tgaaccatct tttgcattgt
    16201 gaataaaaca aactttattt ccagtaagct tattccattc atttgaaaat gcaggtgcta
    16261 tagtaccatc accttctgaa gtctctagct cacatctcat atttataatt tcatcagtac
    16321 tcaaatattc aaaacaattt tcatttggaa tgatgctctc ttttggattt cccaatcctc
    16381 tagcattgct ttgtcctatt aataagaata catctatatt ttccataagt taactccttt
    16441 acaaaatttt aagcttttaa ttattttcaa ttttctcata aaaaactaag gctgaaaata
    16501 gtaatctaac taaaatttac gaagtctcac taatcgctga aagttaaatc actattttca
    16561 gccctagtgg ttatataaat tatcattatc taaccaaaac cttaaaaata gcttttttga
    16621 tattttcttt ttctaaaact tttattcctg tcatatgagc atcttctgga taacaaacta
    16681 aaaaatcacc ttttctaagt tccatgtatc cattattttt accatcaaga ggcaagaaat
    16741 cgcccttttc ttcatatatt ttttgttcta aattttctat aaaatttata tctattcgtt
    16801 cacatccatc aagcatcaaa tgaacatcta tatacttctt atgagcttcc cagaatctat
    16861 cttctttttc acaagtttta tactctacaa tattcacaaa aatatcatca ccatctattg
    16921 tataagtacc tttttcataa tctattaatg aattatcttt agcatattca aaacatctaa
    16981 gtaaatcttc atgcaatgtt gaatatgtct tactatgatt tatatttcca aatatcataa
    17041 gcactatctc cctatataat tataaagtct atttttatac ttttatatac aaagtatatt
    17101 atacaatctt atagagtaac taaattattt atctaatcac tctataagac aatttatcat
    17161 ttaaatatta tttttcataa taaacagtag tctcagcttt tggtaaagat acttttgctt
    17221 taactttagc ttctattgca ctaactattg tacctaccac tacagaagtc gtgattgtta
    17281 ttagagaata tgcccaagaa gttacttctg gcatacggta ttttaaataa acaactaaaa
    17341 ttgctgatac tatgaatcca acatatgctc ccattttagt cgctttttta caaaatgcac
    17401 caagtacaaa tattcctgct aaaacaccta gtactagccc cataaaacta ttaaaccatt
    17461 catatgctga ctttatttct ccatttgcta atactattgc aacagctata gaaagtatac
    17521 ctacacctaa tgatatatat tgtgctatct tagtttgctt ttccatactt atatcttttg
    17581 ttatgatagt ttgtatatct aaagtccaac ttgtagcaac tgaattaagc cctgtcgata
    17641 aagttgattg agaagctgca tatatcgctg caagtagtat tcctgttata cccactggta
    17701 attcataagc tatatatgat gcaaatactt ggtcttgttg aactgtttga gctaaatctg
    17761 ggttttgagt atagtatata aataaacaag ttccaattag ataaaatact gttgcaagtc
    17821 ccattgataa aacaccattt ccatatgtca ttttattaag ttgctttata tcagttgttg
    17881 tagtaaatct ttgaactata tcttgactcg atacatatga tgaaaaagta ttaagaccag
    17941 ctccaataaa tattataaat gcacttgtag atagtatatt tttatcaaac ataacttcat
    18001 tacttgctaa gaacttgtgt ccagttgtaa gagtatccat tactgttcca aaaccaccat
    18061 ttatacttgc tattaaatag aacaatgtcc ctgtaacacc tactattaat accatacctt
    18121 gtataaaatc tgtccacaag acagccttta atccacctgt atatgaataa attattgcta
    18181 ttacacccat aactactatc aatacattta caggtattcc tgtaagacca gctagaacca
    18241 ctgatggaag atacattatg atagacatac gtcctatttg atatattata aacatcaaag
    18301 ctccaagtac tctaagacct ttactttcgt atctcatttc taagtattca tatgctgtat
    18361 ctatttctaa cctactatac agaggtaaga aaaattttat tgtcaaaggt attgctataa
    18421 acatacctaa ttgtgcaaac cacaaaatcc aagtaccacc ataagaattt cctgctaatg
    18481 ataaaaatga tattggactt aataatgtgg caaatattga tactgatgta acccaccacg
    18541 gaatagttcc atcacctttg aagaactctt ttcccttcat ttcctttttt gaaaataaca
    18601 atcctgcaaa taaaactgcc aataagtaaa ccactagtat tgcaaaatct atccaagtaa
    18661 atcctaccat ttgactaatc ctcccatact aaaagtattt tattaaaaat actttctgta
    18721 tatttctttt gctcttgatt tcatttcatc agttgcttct ttcataggtt gtctacagta
    18781 tccagcctca acaccttgtt cttcaagtag taatttaatt gtttgatata agccatttcc
    18841 taatatatct gttattaaat cattagtcac atgttgtact tcaagtgctt ctgatatttt
    18901 ttcattctta gttaattcga atatttgtct agctctgaca ccgtttacat tgaatgtaga
    18961 accaattgcc ccatctacac ctaaaactgt agctggtaac atcatttcat caaatcctgc
    19021 aaatattaat ttatttggga atgtttttct cattctctct aataagtaga aatctgctgc
    19081 tgtaaactta acacctatta ttttttcatt ttcaaataat tctccaaact ggtctaaact
    19141 catatcaaca ccagttaaaa atggtataga gtatattatt aatctattat ctacagaatt
    19201 tattattgta ttataatagt gttttatttc ttcaaaatca aatttatagt aaaaaggtgt
    19261 aacagcactt attgcatcat atcctaaatc agttgtaaat ttagcaagtt ctacagcttc
    19321 ttttaaatta actgaaccaa cttgagctat taattttatt tcttctttca cttcatcttt
    19381 agctatttca aatattcttt tcttttcatc agttgaaagc atgaagtttt cccctgtact
    19441 tcctcctaca taaagaccat ctactttaca aacatctata ttgtgtctaa ttatttgtct
    19501 taaccctttt tcatttatat tcccttcctt atcaaatgaa actaataatg ctgaataaat
    19561 tcccttcata tctgttgttc tcatatcttt acctccaatt ttaattttca agtatagtta
    19621 aatataataa ttttttaatt tataaattaa tttttaatta atttcaattg ctttaacaaa
    19681 tttttctgtt attaattgtg gtcttgttat tgctgaacct actactgatg aatgaacacc
    19741 caactcaaag acctttttta aatcttgagg agtatttacc tttccttcag ctattacagg
    19801 tatttctaaa tctttaacta atctttccat taatacaaaa tctggacctt ctaatgtttt
    19861 agtatatgga gtatatccag atagtgtagt tgaaacgcaa tctacaccgt actcttgtgc
    19921 tttgatagcc tcatcataat ttgaaatgtc tgccattact agaacaccgt tttcttttat
    19981 atactttata agttctttta agtcttcatt atttggtcta actctattgg tagcatctaa
    20041 tgctatcatt tcacaccctg ttgttaaaag ttcatcaact tcttttttag ttggcgttat
    20101 atatatatct gaatcttcat agtttctctt tataatacct ataacaggaa gtccagtaac
    20161 tttttttatt tcaataatat cttcaactcc ttgagctcta attccaacag ctccaccttc
    20221 catagcagcc ttagccattc tccccattat aaaaggacta tgaagaggtt cattttctaa
    20281 agcttggcat gatactatta atcttccctt taccttatct agcatttttt aaattacctc
    20341 gtttctgaaa tttattttct tgatttatgt attaataata acatgaaaac tttttctttg
    20401 caatattttt tcatattttt ttctcgcatc tatattttta ctgatttatt ttatatatta
    20461 gcttgttttt tacatttaaa agaaatttta tttcattttt ttggtgttta ttttcatttt
    20521 atataactac tgttataagt ccatttaaat aatttcaata aaaaaaccca tgtatactat
    20581 acataggttt cccaatatta ttctaaatcc attataattt ttcttccaca gcatggacaa
    20641 aattcagcct ctgtatctat ctcactttca caataaccac aaattataaa atcatcacat
    20701 tcattttcca attcaaattt tttaccacat tcagcacaat atttatcatt tacatttcca
    20761 acataaccac actcacaagt tacattactt tctgccattt ccatttcatt aatttccata
    20821 tttttttcat aaattaactt atcaagttct agtaactcat cacagaattt atcaaaacta
    20881 ttatcattaa tagaatcttc tctaattttt tgatatgtca gtattcccat ttccaagaat
    20941 atctttgctt tcttttcttg aatatcatca atctctctat ttaattttga tttttcttta
    21001 tataattcaa ctttaaattt tccactacca aactttttct taaccttaga aaatttatca
    21061 tctactttat tattagtatt tccttccaca gaaattccct ccaatcatat ttaatcagct
    21121 gaatttagct tatatcctat taaagatatc acaaaactat atacaaatga aattacaata
    21181 gcttgtaaga ctttaaattg cattattaaa gttgttccat aattagttgt attaaagaaa
    21241 ttaatattac tatctagtat aaatgtacta aataaagcca atattcccat caaaaatgca
    21301 taatatatac taaatactat tataggtctt atactatctg tattatactt aaatcttagc
    21361 ttgtatccat ttaataataa tattaacata gacaatgctc ccattgcata aaacattaat
    21421 ttagtatctc caaataaaga tgaagaactt aaagtaaaca ttgatactgt tgagtttatt
    21481 atggttactg aaattccatt tgcaaaagcc cacatataac tagctatttg tgggagtata
    21541 gtaaataaat ttaatccatt tgaataacta ctcatatcta gttcatttaa gtaactacta
    21601 tcagatatag ttagtaccaa tagtattact aatactaaaa cataacctaa tatgaatgtt
    21661 cttatagaat ttgaaaaaag agataaatac atattttcct tttcataact ttttttataa
    21721 gtagttatgt atgtacatat aaaccctaat acaaatccat ttaaaagaac actaaaaaat
    21781 tcataactat attctaatgc atatccatat tctaacatac tatgtgaact agtttttaca
    21841 ttagtaaaaa tagataaaat agctaaaact aatccataaa aaattccaac tcctagagaa
    21901 tttgctaata cagtttttga atctctacat ctttttctca taaaaattag gtttgatatt
    21961 aataatacca aaatagggat tataagtaat atcaacaaac ctatattggc atttataaac
    22021 ccagaaccca tcatggtaga catagataca ctaatttgac ccaagttgag agctaggatt
    22081 atatgtgctg gatttattaa ataactaata tcattaaatt gaatagttat aatagcttta
    22141 aatatcaatg caataataaa caatataaat atggttgtaa atgttgttaa aaatacacct
    22201 cttttatttg catgatatga aagctctttt attttagatt tcaagtctag ttttgtttca
    22261 agtggtctta atgatgctat ttcataaagt tcatttccac aaaatttaca gtaattatcc
    22321 ttagtattat tttctttatt gcaactagaa caaatttttt cttctttact tttaagagtg
    22381 atatggctat tttttatttt tctagttggt tcacctgtct ttttggaata attattatgt
    22441 gaataattca tattatttat tttcttttca cccatttttt ccctccaagt tttactattg
    22501 taaattatca aatataacta tatcatataa aacttaatta taccttaatt ggatatattt
    22561 atctatttta tttgtttatt gctgttgttt tttaacaggt cttgatattt aaatagtttg
    22621 ttaatgcgaa ctttattatt tatattttat tatgcttaat ttaaatttat tctattcttt
    22681 attttcagca gcaaactatc tgtaaatctt aattatagta aagtattaat taataaagtt
    22741 actcaacatt agctaataaa ttttatctat cacaatttta gattgttaca cacaatatat
    22801 tttgatataa ttaaatcata aacgaagtat tccaaatatc taatgataga aaggaatact
    22861 tatttttatg ctttattttt aatggaggct tatatgaact tagaaaaaat aaaaaaattt
    22921 tttggatttc ctctagacaa aaaacacaaa gaaaatgttg aaaaagaact ctgcaattat
    22981 ctttatcata cgggtaaaat catttgcata ataatagtaa tatctcaaat aattatgatg
    23041 atatcaatct cagctagaga aggaggccct tttgccacac caagacgcca atggtatttt
    23101 tatatgtatg taacactatt ttgtgtatct tctgtcttta tgtttgtatt ttcttatctt
    23161 tggaataaaa aaaaggattg ttgtacgttt tatataaatt tatggataat ttatgtgact
    23221 tttttctgcc tatggggttg tgtaattact ctacttgacc agttaggtgg aaatgaccta
    23281 agtgtattta gttatattat gttagcagct gcagctttct cagtattaaa atttggagaa
    23341 tcagtaatag tttttggagg atgctttttg tttcttaatt tattcttacc tgggattcaa
    23401 actataccag gcaatgagtt tagtaatatt gtcaacacat tttttataac atcccttgcc
    23461 atttttgttt ctacaatgct atatagaaat cgtgtattta cttactatga taaactttta
    23521 attagtcaac aatatgaaga aatatctcat ataaataatt tacttaacga caaagttatg
    23581 acagacgacc ttactaaaat gaacaaccgt agataccttg aagatattct acaaaaaaaa
    23641 ttaatcagcc atgcaaatca agaacctata actggaatga tgatagatat agattatttc
    23701 aaacaattta atgataatta tggacatcaa aagggagact attgtctaca aaatattgcc
    23761 aaagtaattt tagattttac aagttctgaa aatgaacatg ctatacgata tggtggtgag
    23821 gaatttttta tatgtatttt taactgtgat gagacagatg ctaaacttaa atcagaatgt
    23881 ttacgaaaaa ttatagagtc ctgcaatttt gagcgtgatg atgttccttt aaaatgtgta
    23941 actgttagta ttggagttta tacaaagaaa attgaaaagg caataacatt aaatgagttt
    24001 ataagtaatt gtgataaggc tctatatact gcaaaagaac agggacgtaa ttgtgttgca
    24061 ttttattaaa aagttacata ctattatata aacctataag tattatatcg caaaataaaa
    24121 gtaatcaaat tatatattta tagtacaata aaaataactt gcatatctct aaaatagata
    24181 aatatgcaag tcattttagt gtttatactt aaagttatat aagttttatt atatataatt
    24241 attaaaattc agcattttta ggagttcttg ggaaaggtat aacgtctctt atgttagaca
    24301 tacctgtcat atacataatt attctttcaa atccaagacc aaatccagag tgagtagcag
    24361 taccaaactt tctaagttct aaataccacc aataatcttc ttctcttaat cccatttcat
    24421 taattctatc taacaataca tcttctcttt cttctctttg agaacctcct acgatttctc
    24481 caactccagg aactaataaa tccattgctc taacagtttt accgtcttca ttcattctca
    24541 tatagaaagc ttttatatct tttggataat ctgtaacaaa cactggacaa ttatatattt
    24601 gctccgttat atatctttca tgctcagttt gaaggtcaca tccccactca acaggatact
    24661 caaattcatg accagattca attaataatt ccactgcttt agtatacgtt attctaataa
    24721 actcagagtt tactatctta tttaatcttt ctaacaatcc tttatctata aaactattaa
    24781 aaaattccat ttcttcagga gcattttcta atacatagct tataacatat tttatcatat
    24841 cttctgcaag ttccatgtta tcttcaaggt ctgcaaaaac tatttctggc tctatcatcc
    24901 aaaattctga agcatgtctt cctgtataag agttttcagc tctaaatgta ggtccaaaag
    24961 tataaacgtt tctaaaagaa agtgccatta tctcggcatt tagttgacca ctaactgtta
    25021 aattagcctc ttttccaaag aaatcttgag tatagtctat tttaccatct tcagtttttg
    25081 gaatatcatt taaatccata gttgttattc taaacatttc tcctgcacct tcacagtcac
    25141 tacccgttat gattggagaa tgtgcatata caaagtttct ttcttggaag aatttgtgta
    25201 ttgcataggc agctattgat cttactctaa atacagctga aaaagtatta cttcttggtc
    25261 ttaaatgtgc tatcgttctt aaatattcaa gcgtatgtct cttcttttgt agtggatacg
    25321 aactatctga ttccccttct acaactatgc tttttgcatg tatttcgact ggttgtttag
    25381 ccccttctgt agatactaac tctccctcta caagtataga tgagcttatt gctaattttc
    25441 ctacctcttt aaaattttct actttctcat caaatactat ctgcatattt ttaaagaagc
    25501 ttccatcatt tagctctata aatccaaaat ttttagatac tctagatgtt cttatccatc
    25561 cagctacttt tacagtcttc cctatgtact gttctttttc tctgtacaat tcttttactg
    25621 ttataaattc cttttgcatt ttaaatcctc ctagtataat tgttattaat ttcttttaaa
    25681 tataatttca ataaaaaaag cccttcatcc ctatataaag ggacgaaaga ctattactct
    25741 cgcggtacca ccctagttgt cataatgacc tcttagttaa gcaatgctta aagcctataa
    25801 cggtgccttc cgtctaagtc tacttactaa ataagctttc gattagaaac tccaagatgt
    25861 tcttcaatat aaacctcgta ttgagctttc accatcctca actcgctaga actacatttt
    25921 atatctactc ttctcttcac agtatttatc ttttattatt tctactaatt aacaaaatta
    25981 taccaattta taaattttta gtcaataaat ttatataatt gatactgatt gttatttaaa
    26041 atataataat tctaccttgc ataatgataa taaatactta tcttcattac ttctttatta
    26101 cttaaatttc caaaatttta taatttactt ccattgtcaa cccagtcttt tgcttcttcg
    26161 acacccttaa ttgaaggtat tgaaacttta ctatgaggtt ttaatttttc aacatcagcc
    26221 catgctgctg tcgactcatt tccaactaaa agtgaacttt taagtctttt attatcttta
    26281 ccttttaatg ctcttgcctt tttactttcc aaaactatca cctctattat ttattttgta
    26341 atagttttag caattttaca aataaaattc ataagtctaa attataatga tttttaaatt
    26401 aacatcatat cttttcaata cttaatttat acctatttat atacaaaata tttactttgt
    26461 gtattcaaaa tataaaactg tttttttaat tttcatattt attttttatg ccatttttct
    26521 actctatcta aagtatttga tacaattaaa ttactaatca attataattt tacataggtt
    26581 cttatctata gagtatttgc tatctgttga atcgtatttt ttaaatttaa aatcccatat
    26641 ccctgcgata catttggata tgtatatatc tcaagttttg tagcacccaa tattaaatat
    26701 gtttttaaaa cttgtgtaaa caatgataat ctcggtacat tatcctgttt ttctaagtat
    26761 tccatcaata aggctaaaac acctgtgact atagaactgc tcactcctgt tcctgttcct
    26821 gtattatatg ttccattttt atatgtggat attatatcta cacctgaagc tactatatct
    26881 ggcttaattc ctcttcctct aattggtcct ttcgaagaac caatccacat actatcagtc
    26941 ttattattaa atgtaccaac tgtaattaca tcatcactag cagcatacat agttatagta
    27001 gctactgaat cagggtctaa aaaccttgtg tctggagcta tcaaattttt atttggtaag
    27061 tatatgtcat attctccact tattataagt tctgaagtca atcttaaaat ccatactcca
    27121 ggttttatat ctcttaatct tatctccaaa ttttcttttc cagaggtaat atatggataa
    27181 ataaatctca ttgcataagt agtattttct aagttaaatt ttcctctata tatataaaag
    27241 tctggagaat accttatatc atgactaact tcacctgaag gagatattat ctgtgctccc
    27301 actttatctg gaccattcgt atttagtgtt atatcaagag catagtcatc tccatcttgt
    27361 attattacat cttgaacttc tcccacactg ctaaatctgc cagaataatg aatatctgta
    27421 ttcccttgat ttcctgcacc actcactact accacaccag cactactcaa tatattaaaa
    27481 gtatctaata ttgaagtagt tgctacagca cttgacttaa ctccaatagt caaatttatt
    27541 attagtggtt tattttctgt tcttgctata ttagtaacat acgttatagc tgctaaaaaa
    27601 tctgaaacac tataatttat ccttccagca taataagtat ctgtatatga ttttaattta
    27661 actactatta agtctgattc tgtagtaata cctctatact gcgaatttat ccttccattt
    27721 ccagctaata taccagaaac taaagttcca gtacctatat tatcttgact caaacttcca
    27781 tcatttctat ttatggctat atttaactga cttcttgtaa attcacttcc aaaaataaaa
    27841 ccttctggag gtggatttgt atttgcttct tggtcccata aatatagaac tttactagtt
    27901 ccatcatcat ttataaaatc aggatgcaaa taatctatac cagaatctat aactgctaat
    27961 aaaattcctc ttcctgttat atcattatat ggattttcat aaatataatc agtttcagct
    28021 gctgttgtaa tggtttctcc attatttaca ttattagtta tttcaattag actgctcatt
    28081 ggttcagatt cttcccacca agcaacttgt attatattat ttaaaatagt ttcatcaaaa
    28141 tctacaggta catatattac tgcaagctga ctatttaaaa ccatatacct atttattcca
    28201 ttttcttgta gggcagattc tatatcacct tgataaatta tacaataaga tttttccata
    28261 aatccctcct atcttaaaac atcaaacatt cctctaacat ccaaaagccc atatccagaa
    28321 tttgtatttg gatatactgt gtttgaatct tttctagcac cagcttgcat aaaagttttt
    28381 attttttgca catatgcttg gtttggatat ctaccatcaa caaaagtata ttggaaatac
    28441 attgcagcag caccagctgc atgtgcactt gctgctgctg taccagttat agttgcatac
    28501 gtgttcccag gataagcagc tattatattg acacctggtg ctactatatc tggttttaac
    28561 ctgtcttcaa tagttggtcc tcttgatgaa ctttgccata aactaccatt aatagtattg
    28621 taggctccta cagttattaa atcatcttga atagcaggat aatttatagt gtaaaaaggg
    28681 tctacctctc taaatctagt tccacttttt aaaagttctc tatttggaag gtataagtta
    28741 tatcttcctg ttataatata aacccctact aatcgaatct tccatacacc tctttttgca
    28801 ttctttaaag taacattagt aaattgctgc ccagaaaaag ttgttgggta tatatacgtt
    28861 atagaatatt cagtcccctc taaatcaaat aaacctgtta ctttattata atttgaaatt
    28921 ccaacacttt tactttcttc accagtggga gatactatta ttacatcagc tttatctggt
    28981 ctatttaacc aaagttctaa tgataattct tcctcgtctt catttaactc taattcaact
    29041 tcaacagaac ctccaacatg tggtattatt ccagatgtat gtgtctgtgt attgccctca
    29101 tttcctgctc ctgctgttat acataaccct ctagtaaaga atgctttttc actattgctc
    29161 ctattggtta aacctgccaa gctactggta cctaaagaca tatttataac tagtggtctt
    29221 ctaagttcaa aagctttttt atatgcatac tgagatgcag caaacaacat tgcactatta
    29281 taaaaaccat ctatcttacc gagttttatt attattagct cagaatcttc tgctatacct
    29341 gcatattcac tatttacatt tccaagccct gagcatatac cactcaacat agttccttga
    29401 ccaacttcat cctgagatag actagggtca ttttctgcga tagctcgatt tatatcttct
    29461 cgtgtatatt ctgtcccaat ataaaaacca tcaggtggag ttccttcttt tgtttggtcc
    29521 cataaatata ctatttttga agtaccatct ggataaataa aatctggatg tagatagtct
    29581 attcctgtat ctgcaattga tattagagtc cctcttcctg ttatattaat attaggatta
    29641 tttttaaaga aatttacgcc catttcttct gttgcaacta cacctccaaa agtacctcga
    29701 ttaatttctc caagtaatgt catctttgta gtcgatacag ttcttatgat tgaaggaagt
    29761 tgcaaaactc gttgtatact actatagtct gtattattta tagatagtac acctaatgaa
    29821 tcacttatct taaaaaaatt ttgactcata cctaacccag ctagttcttc ttcaaattcg
    29881 ggagtatgga ctacatctat tcctgatagt attcctgatt gtctacttgc atttttactt
    29941 atataaattt cattctctaa gtcattatgt atttgtatat tataaccatc tataaactta
    30001 tacctatttt cctcatcttt aaatgactta ttaatacttc tatatccaat atcctccgtt
    30061 tctaaatctt gatttatact agatagagtg tacaaatcta tatctgataa atttaaaaaa
    30121 ccaaatcctg atgaattatt tggataagat tgattactta atctccttgc tccctttaaa
    30181 agtaatgccc ttaatttctg tgaatacaaa aataaatcat ttccatttac aattccccat
    30241 tccataaaca atgaacaaac ccctgtaaca tgaggtgtag ccatgctagt tccagttaat
    30301 gctccacttg tacctcctgg taaaaaagat attatatctt cacctggagc taataaatca
    30361 ggtttaaaaa cacctaattg tgtatctcct tcaccagaaa atatagatac tatgtctgtt
    30421 cttgaattaa aactacctac tgttacaact ctacttgctg ttccaggaac tgttacagta
    30481 agctcttgag taggaatcag aaatctagta tttctattta gtccttcaga agttggcaaa
    30541 tatatattta cattaccagt tactatatct attggttcaa atacaatttt ccataaccca
    30601 ggagttatct gtgtatttga acttaattgt agagtaactc ttcttgtaag agagtacggt
    30661 gctatagggt aaaaataacc agttattcta gtttcaccca aagtatttct tatctcacct
    30721 gaagttagag agattgcttg tgtttgattg tttgatgggt ttaccaaatg tacactaaaa
    30781 tcatcaacaa aatctggcca tatatttatg tttaatatac gctctccttc cccaactata
    30841 aactcaactt cttctgtaat attattttga agcctaatcc ttttatgacc tcctttatct
    30901 gcattatttc cagctgctac aactatattg tttttccaaa ataaacacat atcatctata
    30961 tattgttcaa ataaagatgt tcctctatgt gaaccttcat tacttccata acttatattt
    31021 aatgtaacag gcattcttaa ttctaatgcc ctatctaaaa taaatttaat tgccctcata
    31081 aactctgtac ttctcgaaaa aatatcggtc tgtatatttc caactctaac cactattatt
    31141 ctggcatcac ttgcaatagt tgcacaaata cctgcaacat gtgtcccatg taaactagtt
    31201 gttgaaatag gtatatacat acttccatct attgcattat ttatatcttc attagtatat
    31261 aatgttcctt ctctaaaacc ttctggtgga tttccttgaa tagattggtc ccaataatat
    31321 aatatcttag acctcccatc actatctcta aacacaggta gagtataatc tattcccgaa
    31381 tcaattatac caattatagt tccctttcca gttaaaccag ttctattttt aaaccccgtt
    31441 attcctgtac ttgaaaaact ttgcacatcc tgagtctgta atataaaagg cttttctata
    31501 aattcaattt ctggataagt taaaagtgta tttacatctt cttcattact tgatgttatt
    31561 attgcatatg atgaattaag tatctctact gatacaccta attcttcttc taatctcaat
    31621 atatctccat tgtattttac aattaattca taatttatta taatcacctc gacttctaaa
    31681 attattatta atgtatatgt tttgtgtaag tctaaaatgt attagactat ataatttttt
    31741 aagtttcagt tatacaattt ataatagata tattaaaaaa taaataatga tggtacaatt
    31801 ttgaataaat cataccatca tttatattta ctttatcttg aaagcattaa atttttcaat
    31861 gctttttcaa gaccttttac agtcagtgga aacatattaa attcactttg tatcattctt
    31921 tgagtttggt accaataatt aattgaatcc catccatctc taagttctgg attcatccat
    31981 acaattttac tgtactttct cttaaacctt ttaagccatt ctataccagg tgtgtaatta
    32041 tatggaccac gatagttacc accaatatga agtaactcag aaggcgacat agaagcatct
    32101 ccaacaatta taactttata gtttttatct atatttttta atatccattc agtattaata
    32161 gatttactta accaacattc aggtgttgta aataatctat cataaataca gttatggaaa
    32221 taatatatct ttacatcttt aaaatgattt gatttactta cagactgaaa taatgtatta
    32281 cataaagtgc tataccccct cattgaacca cctgaatcca taagcaataa aagcttcact
    32341 gtattttttc ttggcttctc aaaaaataac tttaaatatc ctgcattatt acaagtctct
    32401 tcaatagtct tatccaaatc aagctctgtc tttggagcat ctattctagt agaaaattga
    32461 cgaagtctct ttagtgcaac ttgaaattga cgcatattta aaacttcatc atctctaaaa
    32521 tctctgtatt ttctttctcc tgcaacttca agaacagctc taccataagt agaatttcca
    32581 cctatacgta taccagtttg cccttttcct gaatgtccta actcggaagt gcctcctgtg
    32641 cctatccaat aattaccacc attatgagga gagtcttgtt cttttattcg ttcctccaat
    32701 ttagctctta atttatcaag atttatattt ggattttgtt ccaatctttc aaactcttct
    32761 aaatctatat ctggtttttt aagccaattc ataatctctt ctggaatttc ttcttggtgt
    32821 tctatacctt taaaatactc caaaaacact gcatcaaact tatcaaaatc actttcactt
    32881 tttattaaaa tcatcctgca aagatagtaa aaatttgaaa agtttgaata gcacagccct
    32941 ttatccaatg cttcaattaa agtcatccat tcatttaaag atatatttaa tcctcttgac
    33001 ctcaataaat aaaaaaattc aataaacata attatccagc tcctattaac tataagtgtc
    33061 tttgcataga ttcaatatcc tcattattct taagtagtat tcctgcaaaa ggaacttctt
    33121 tttctatttt ttcaataggc attccactca aagttaatgc ttgtatccag tctattaact
    33181 ctgatgtact aggctttttt tgtatgtcct ttaaacttct aatccaataa aaagtagtca
    33241 ttacttgttc caataggtgt tcttctactt tatcaaaatg tactttaact atttcttcca
    33301 tcatgtctct atcaggaaat tctatataat gaaatataca tcttcttaaa aaagcatctg
    33361 gaagttcttt ttccgcattt gaagttataa taactattgg tctttgttta gctcttacag
    33421 tttcttttgt ctcatttatg taaaactcca ttttatccaa ttcccaaagc aagtcatttg
    33481 gaaattctaa atccgcctta tctatttcat ctattaaaag aattacttgt tgatttgagc
    33541 taaaggcctc tcctagttta ccatatttta tgtacttgct aatatcatct acaccttctc
    33601 ctccaaattg gctatcataa agtctttgaa cagtatcata tacataaagc ccttcttgtg
    33661 cttttgtagt tgattttata ttccaaatta ctaaatcttt ttttaattca tttgaaattg
    33721 cttgtgctag catagtttta cctgttccag gttcgccctt aatcaaaagt ggcttttcaa
    33781 gagcaatagc aacattaact gatgccatca attctggtga tactacataa tcactacttc
    33841 ctctaaagtt agatatctct ttttttatca taaatcctac tccttttaaa cagtattttc
    33901 taaatgtata tagactttat tactattttt gatataaaaa taataataca atacatttgt
    33961 atagtattat tctaaaattc tatatctaaa taaaatcacc tctaaaatat ttaattttta
    34021 tctttatttg tcataattaa atgaaatata tattttaaag aataataaaa gatagcttat
    34081 tgtacaaaat ttaaattata aaaacttagt ttaatcaaag gcaccacttt ttttcatttt
    34141 agattatata taaacataat ataaataatt tttattattt tagctataag cataaagttt
    34201 taacgtattt ataatttcat attaatcata ctatattaat actgcttttt attgtataat
    34261 aagctataaa tattaacttt aacttagatt taagtatatc taaatttaat aaatataaga
    34321 aaggttgtgt tattttgcaa gataaaaaaa tttatctaaa tattgtactc actgtagttg
    34381 tttcatatat cttgattaaa gttattgata attacaaata tttttttgga gtgataagtt
    34441 tattaatgtc actactaaca ccatttataa tagcatttgt attagcatat atattcaacc
    34501 cactagtaaa gttcttagaa agtaaattaa attttaagag aatatattcg ttacttctta
    34561 cttatggtgt actcatagtt atactaattt cctttatatt atttacagtt ccatccatag
    34621 taaatagttt agctgattta gttgctcaaa ttcctacata catagataaa acagagcagt
    34681 tcttattcga cttaggtaag agtttacaat cagttgaccc taatacatta aaagagtatg
    34741 gtgacaaaat tatgagtgta atgcctaaat ttagtaactt gcttattggt tcacttggtg
    34801 ggatatttag cactacattt tcagttggaa aatttatagt acaatttctt ttaggtttta
    34861 taatttgttt ctatatatta ttagaaaaag aaaaattctt actgtttaca aaaaaagtag
    34921 tttatatttc cctaggtaaa aaatatggag actttataat agaactatgt caaagcttaa
    34981 atttaaatat tggtaaatac tttacaggta agattttaga ttcttttata gttggagtac
    35041 tttctggaat tggtctttac tttttaaaat ctgaatatgc actattattt ggtacactta
    35101 tgggtgtcat gaatatggtt ccatattttg gtccagtaat aggtatggca ccagttgtaa
    35161 taattaattt attctccaat ccaacaattg ctttaacttc tttaatttac ttaataataa
    35221 ttcaacaagt tgaagttaca tttatagagc caaaaatcgt aggtggacaa ctaggtctta
    35281 gcccattctt tacaatccta gcagttactg ttggtggagg attctttggt atacctggta
    35341 tgattctatc tgctcctgtg atgggcgtta taaagatata cttctgtgag tttgtaaatc
    35401 gtagacatga taaaatacaa atggaataaa aatacaattt aattacgatt ttgtaatcaa
    35461 aagttacagc tgtgtaactg taatattatt ctctttaatg gtaatattta attataggaa
    35521 acatacaata ttattaagta atgaatctta tataattaaa catgaaagag ggttttagta
    35581 tgaaaaaagc acttatatct ttattagttt tatcttgttt gttattaact gcaccagtaa
    35641 atgaatcttc ttatgcagat tctcaaaaga atgttcctgt aagccaaaat actaaattga
    35701 ctcaagaaca agctaaagaa cttttagtaa aatacaacaa tgaagttgat tacatatatc
    35761 aaggaaatgc tagtgatttt gaagcattaa aagctaaaaa tcttaatggt tatgtatttt
    35821 taccagatgc agatggtgat attggttact ttgtaaatga aaatacttct gagatatatt
    35881 acttccaccc aagtggatat cttgaattag ttaatcaaca acaaaataat aaataactaa
    35941 taaaaaatgg atgcaaattg atataaattt gacatccatt ttctttttat tttaaagttg
    36001 tttcttttta taaactttaa atactttttt aatcctgtgc ttgctctttt ataagtttct
    36061 ttatatctac agcaggttca tcttccattt ttataacttt tccttcccat gttctaagca
    36121 taacgtaatc tgttcctttt gatacaaggt attgcggaag caaaggagtc tttcctcctc
    36181 cttttggcgc atttactata tatgttggta tagccattcc tgatgtatat cctcttaaat
    36241 actccatgat ttcaagacca tcatctactg atgtattgaa atgttttgtt ccctttacat
    36301 gtttactttg gaatatataa taaggtttta ctcttatttt tagtaattct tgatttaaac
    36361 atctcattac aaatttatca ttatttattc catttaataa tactgcctga tttcctaatg
    36421 gaactcctgc atttgctaac ttttcacaag cttctttaga ttccttagtt atttccattg
    36481 gatgattaaa atgagtattt atatatacag ggtgatattt ttttagcata ttgcaaaatt
    36541 catctgtaat tctttgtggc attgtaacaa gagtcctagt acctaatcta acataatcaa
    36601 catgtggtat ctctttaagt tggctaagaa tccactctaa ataatcatct tttaatgtaa
    36661 gagcatctcc accagttact agtacatctc ttatttcttc attttctctg atatagtcta
    36721 tagattcttg gataatagct tttgacttat gagaatcttg ttgtccaata tttcttcttc
    36781 tctgacagtg tctacaatac atagcacact catttgttac atttattatt aatctatctg
    36841 ggtatcttct agttatacat cctgctgggt ttgtatactc ttctcccatt gggtccaaat
    36901 cttcttgctc atcttccaac tctatatgtg ttggtataga cagtaatttt attgggtcac
    36961 atatatcttc tgggtctata agactcaaat aatatggaga tattgcccat ctaaattgag
    37021 taccaacctc ttttatatat tctttttctt ttttagttag agttataatt tttgataaag
    37081 tatctacatc tgttattcta tttgataatt gccatttgta gttattccaa tcctcttcag
    37141 ttccatttaa gatacttaat attttctgtt ttcgtttatt tatctcttct tctttttcaa
    37201 gacctctgtt aatcgttttt ctagcctgaa tataatcatc aatttttgat tttaattcag
    37261 cagctctctc taaggatatt ctagtttgtt cattcataat tttttgctat caaagttaac
    37321 tacttgtatt atttgatagc gtcctccttt ctgatgtgtt tatatcattc tgataggcag
    37381 atttaatttt gccatataga ttttataaca aatgaaattg aattaatttt tgcatttttt
    37441 ctgttatttc gcacatttat gaatattttt caaccttcgt caataaatta caataaatta
    37501 tgcatttttt ttaacaaatg attaattttt tctattttta agaattattt taccataaaa
    37561 cgattatatt ttcaagatta ttaaaattaa attttttaat aaaaagtaaa gtatttcatt
    37621 aaataataaa agcggaggtt tattataata aatttctccg cctttttatt tatttaatta
    37681 aataatagta aaataaattt aactcttaag aagtgacttt attatattaa gccctttttc
    37741 taattcttct acatcttttg gagctgttac acaaatacga actgcttttg gaactgtaga
    37801 gtttcctact gaaaatcgtt cagcacaata tacttgaact cctagatttt ttgcagaaat
    37861 ttcaaatgat tttccatcca attcatcagg aagaagtaac caacgaaaac tgcaattctt
    37921 atcaccaatc aaattataat ctgacaaaac tttatcagca acttcatttc tttctataat
    37981 tgcatctctt ttctcttcta taattttatc tataatagga gaatataata aacgatgtac
    38041 tatttctgct gtaaatggag aaaccattag attcatatta tatagtgcat tttctaaatt
    38101 ttctatatat cgttttggag caactacaaa tgctactcta agaccagcac ataaaaattt
    38161 agatgtacta aaaatatata tagtattatc actagctaaa gaaaatatgg gagtttgtat
    38221 accgtctcta aaaatgctat ttatagcatc ttcaataatt attatattat attgctttgc
    38281 tatcttggct atctttttac gagataaatc agacatagta tgtgtcgttg gattatgata
    38341 atctggtata agatatatgc cttttatatt ttcattttta caataacttt caagatattc
    38401 aatcgatatt tcattatttt cttgaggaat tgggactaat tgaataccta tcattttagc
    38461 tattgactta attccagaaa aacttaaaga atctgtagca attctatcac cagctttaaa
    38521 taatcctagt aaagttgcac atatagcatt ttgccctcct gtagataata atatattttc
    38581 ttcactggtg tatacattat ttctttctat ccattttgca attgactttt tttgcatata
    38641 tgtgccagat ggagacatgt attgtaaaaa cctatccatt tctggttgtt ttagtacatt
    38701 tttaataaag tcaataatat atgtattttg ctcatatgga ggatgaactg tccctaattc
    38761 aattatgtct tttgattccg tttgatataa taatgtatta cttacattta catcagaaga
    38821 aatgaatgtt ccctttccca cttttgcaca tattagtccc ttttcttcgc aaagtttaaa
    38881 tgctcgtgtt attgtactta agtttaaatc tagaaaatct gctaattccc gttgtggagg
    38941 cagtttatct ccaggattta aatttcctct tttaatatct tcttctaata acattgctaa
    39001 agttttatat attggtggtt ttcggttatc taattttggt ttccatgtca taggatagtt
    39061 ttcaaaagaa tttattggca tataattact cctcttaatt ataattgtac tccatacaat
    39121 tttattattg tatgcttcta ttttagatgc tatacttgta tttgtaaata gctatttcaa
    39181 aataaataaa taagagaggt ataatatgaa gactataggc ttaattggtg gtatgagttg
    39241 ggaaagtacc attacatatt atcaagttat taatacagta ataaaagaaa gattaggtgg
    39301 actacactct tctaaatgta tactttacag tgtagatttt caagaaattg aagaatgcca
    39361 atctagtgga aattgggaaa aaagcgccaa aattttagct gatgctgcaa ttaaattaca
    39421 agaggcaggg gcagatttta ttgttatctg tactaatact atgcataagg tatcagataa
    39481 aatacaagaa agtatacata ttccattact tcacatagca gatgtaactg ctacagtatt
    39541 aagggaaaaa gaaataaaaa aagtggcctt attaggtact aaatatacaa tggaacaaga
    39601 tttttataaa aatgtaatta ttaataatgg aattgaagtc ttaattccaa atgaagaaga
    39661 ccgtataata gtaaatgaca caatatttaa cgaactttgc ttaggaatta tatctgaatc
    39721 ttcaaaaaaa gctttcttat ctattataga taagcttggc aaacaaggtg cagagggtgt
    39781 tatattagga tgtacagaaa taggtctttt aattaaacaa aatgacactt ctattccact
    39841 atttgatacg acagtaatac atgcaataga agccgcacta agttcaattt aagacaatat
    39901 tgattaataa aaaaaatatc tatagatttg tgtaaataag actttttata atttatatta
    39961 ctagagattt taaacctata tattgtaaca aaaaaaggat agtataatta ccctatacta
    40021 tcctttttct taatttaata tttaaataaa ctcaacactt tcaatttgta tacaaatcta
    40081 tcttacattt ataacatcac tattttgaga gctatttcca ttataatttg caacaacata
    40141 aatatctaga tttaaatctc cttcaggaat acttatagta tgctcatttc cctgtatatc
    40201 actttgatat agattaaatt ctccatctcc attagtatta ttttttacat atatactgta
    40261 agtacagtcc ttatgagata tactactcca gttaactcta atgacattat tatctctatc
    40321 aacattagct gatatatttt ctaccctcat atctttaata ttattatcat tatttgaatt
    40381 tccatttcca ttagtaatat ttattacatt acttggctta gttgtatctg aatccttttt
    40441 ccctatgaca taaatatcaa aatctatatt ttgattaccc ttcatatcta cttctatagt
    40501 tgcatatacc ttgttagact tacctaaatc actttcattt atagttatag atttaatttt
    40561 cttaaatgat tctcctgaca acttatcttt aagatatata tcataatcaa agacatcttt
    40621 catataatcc cattcaagtt taataataac tttattgttt actattttat gtgaaccaac
    40681 caagttttgt atatagtcat tcgttatagt ttctttgact actgttactg ttattacttt
    40741 agatttatct ccacaagtta ttctcaccct atctttacct tctctaagac ctacaacatt
    40801 tccattacta cttaaactta ttgctctttc tacaggtaat tttgaatcta ctaactcata
    40861 atatattttt ggtggttcta aaccaggtgg agaagttatt atatctggtt tcaatttttc
    40921 attttggtca acttctattt ttatatcatc catatttatt tcagcaactc tagcttgaat
    40981 cctaaatgtt ctctcaattt ctttatttcc acacttagca tatattgtag ctttaccaac
    41041 tccaactgca cttactttat ttcctttgat ttttaaaata ttttcattgc tactcttata
    41101 aactggctta tatgattttt taaacttatc ataatcaact tctattgtac tttctatagt
    41161 agcactatca ccaacatgtt ttaaatcccc attaatctcc atatctagtg attctacctc
    41221 tgggtctact acttttatag tagccttttt taatactctt gaatttttca tgatacccac
    41281 agaagaatac ccaaccttta atgctgtcat tttatttcca tctattttta aagtccctga
    41341 gttatccaat acattaaacc aaatatttgg atttttagca tacgaaggaa ccttaatata
    41401 ttcacctgta gacaaagtaa ctgtttcatt taattttact acatatttat ctatatcttt
    41461 aacatattcc ccatctacaa tttcaatttc tactcccttt accattggtc taagtattcc
    41521 aaatttaaaa aggtagtact gcgcaacaag caatatagga atagatataa ttatggcaat
    41581 ttttctgtat ttcttatttt ttacaaatat catctatcca cttcctttta gcctaatata
    41641 taatcatttg ttttgtaagc aatctaccta agttaaatat tgggataaac tggaaaatta
    41701 ttatatttca gaatatccct atactaatta taaaccataa atttaaaatt taaaactaaa
    41761 attaatgtta atttcttact attacaatag tctaatttta gtgaaataac atttgtcttg
    41821 tcagctgaaa agttatataa ttaattaaaa agaaattata cttatattat atgaggagga
    41881 ttttaaattg gaaatcaatt ataaaaaaag aaatttcaaa tcatttgcta aaagaaaaaa
    41941 tattgaaatt tctgttcaaa ggtatcttat tgacgcacta agttatatgg cacttggtct
    42001 tttttcgtcc cttttaattg gaacaatttt caatacatta ggagataatt tcaatatttc
    42061 tctttttact gaagttataa gccctcttgc taaacaggtt actggtccag ctatagcagt
    42121 ggctattgcg tatggacttc aagcacctcc acttgtacta ttttcttgtg cacttgttgg
    42181 agcttgtggt aatgaattag gaggacctgt tggagcattt gtcgctacac tttttgctgt
    42241 agaggttgga aaattagttt caaaagaaac aaaaatagat atattggtta cacctgctgt
    42301 gacaatacta attggagtac ttgtagctga acttattggt ccagctgttt ctgcttttat
    42361 gacttcattt ggaaatataa taatgcaagc tacaactatg caacctataa taatgggagc
    42421 tttagtctct gcacttgttg gaatagctct tacattacct ataagtagtg cagctatttg
    42481 tatgatgtta agtttaggtg gtcttgctgg tggtgcagca actgtaggtt gttgttgcca
    42541 aatggtaggc tttgctgtta tgagctttag agaaaataga gttggtggcc ttgtggcaca
    42601 aggtcttggg acatctatgt tgcaagtacc taatataata aaaaattgga aaatttggat
    42661 accacctact gtagcttcaa tattacttgg accattatct acaacaatat tcaaaatgga
    42721 gaatattcct attggttctg gtatgggtac ttgtggattg gttggacaat ttggaacagt
    42781 aactgctatg caaagtgctg gaaaaggagg tatatctatg tgggttggta tacttttact
    42841 taattttata cttcctgcta ttgtaacttt gttgatttca gaatttatga gaaaaaaagg
    42901 tctaataaaa cctgaagatt taaaactaga tgtataaatt aaaaactact ccttttactt
    42961 atataaaagt aaggagtagt tttttttatg aaaattccaa catttttttt aatagccaat
    43021 ccatagaacc tttaacttca ttccaaacca ctatgttttc atcatagtaa tagacagctt
    43081 ctgccttttc ttcctctgta acaaattctc taccaaaagc atttcgccaa tctaacaaat
    43141 ataatccaac gtacttattt ttacttctag caaccttaat agaatcattt gccaaaaaca
    43201 tacttttatt tttaaagtaa taaagagctt tactgtacat ccatgtagca gatttttctt
    43261 ctttataaag ttcaaataat ttatttattg aagttctatc atttaatcta attaatacat
    43321 ttaataattt gtatcttatt ccctgctcat cactaggatt aatttctatt aaatattcta
    43381 atactttttt ggactccttt agattattaa tactttctaa ctttctagca agggattcaa
    43441 gtgctatcat ataggctctg gtagataaac ctttccaaaa tccaagttct ttatcttctt
    43501 tagtaatcat acttttacct atatttacag cttcctccat atatctaatt gattcaatat
    43561 cactattcgc atcttgtgat agcttaatat atcttttata tagtattttt ttcttttcta
    43621 aatctaaatc tacagacttt gatttggaat tggtctcttt tacccaaaat tctacattag
    43681 aaatagctat agtatcttga tttaaaaagt caatactaca aacatctttt attaaagacg
    43741 atttattatt tatagtattt aaagaaacac ctatttgttt tgaaaactct ttttttgtta
    43801 tatgtagtgg atgcttctta ttgtataaaa gattttgttc taaaactata tttagtatag
    43861 ctgaagacca tatatcagct ctagaagaat gaattatctc tttattatta tctaaaaggt
    43921 tttgcaaaat tttaaagctt atatctttgt attcttgatt taaattggag ttgcaaaatc
    43981 tatttatctt gtccttaatt tcttctatct tgcctgtcat gactcctcct ccatatttta
    44041 catatataaa actagtgcta caaactcaag atcttcttct cctatatttt ctatagaatg
    44101 tttttcgcca tcagctgtat acactacatc accctcattt acttctacaa attccccatt
    44161 atcaaatact ttaccttttc cctttagtat ataatatact tcaaaatctg ttgtatggtc
    44221 atgcacacca attgaacttc ctactggtaa agctactctt ttaaatagtc ttccttttcc
    44281 tttaagctct tcattttgta ttatgttttc aagcttaacc tttcctatac caccatttaa
    44341 attttctttt acttctactt gtaattcaga tttctttctt atcatagctc atcccacctg
    44401 ccaaacaatc aatctaacta ctaaattggc atatcctttc cataaatatg tttgtatttt
    44461 aatataataa taacatatat tatcataaaa aaatattact gaatacacaa aaatgatact
    44521 atttttacat atatttcgac ttaattaaat tatcttacaa gttgacgtct atatgaaaaa
    44581 aacatatact catatagtat ggtaaaattt tgttaaacta tttatctgga ggttctcgac
    44641 atatgtcagt tttaaaaacg caagaaaaac ttaaacaacc tagagattta tatttctgct
    44701 gttcaatatt tacctttgta ggacttgcat actatggtat gaaattggta ttattattgt
    44761 ttttagctga acaagtctcc aaaggtggtt tagggttaac accagcagaa tccgcatcaa
    44821 tgcttgcatc ttttttagca tggacttatt tctctccagt tattggtgga tgggtcagtg
    44881 atagattttt aggtcccaaa aactgtatta tacttggaat gctaatggtt tcaattggtt
    44941 attttctagg atacatagca aatagtaaga tggatataaa catcatgata tttttatctg
    45001 gattaggaat aggtttttat aaaggaaact tacatactat ggttggaaac ttatatacca
    45061 atgatgaccc aagaaaagat ggagctttct ctattacgta tatggctact aatctaggta
    45121 ctttatttgg ccctttaata tgcggtttag ttgctaatga atggtttgct atgaaaagcg
    45181 gattatctat aagtatgtat ggatatagat atgtattttt attttcatca attacggttc
    45241 taataggttt attcttcttt atatttggaa acagaaagtt ttataaacct ttgaataatg
    45301 accctagtaa cgggagagag tctataagaa aatcactaga atataagaaa atgctcgctt
    45361 caagaccttt aactttgatt gagaaaaaaa gaataatagt aatattggtg ttagcttttt
    45421 tcacagtatt tttttggata gcatataacc aagcctctat gtctattgca ctctatacaa
    45481 aggaacacat aaatcttact gttggcaatt ttcaaattcc tacttcatgg atagattcat
    45541 acaatggtct cctttgtgtt attcttggac ctatctctgc tttagtatgg gtaaaattat
    45601 ctcaaactaa aaaaggcgat ttaagtgtgc caaaaaaaat gagcttaggt tttatactat
    45661 tagctatagc atttttgttt atgatagtag cagttataca aacaggaaca gaccctaatt
    45721 caattcacaa agcaagtgta ttttgggtag ttggattttt aacattccaa agtataggag
    45781 aaatttgctt ttctccagtc gggtatggta tggtaaataa actttcgcct gaaaagtata
    45841 tttcattcct aatgggtgtt tggtttttag gcaaatttgc agcaaataaa ttatctggct
    45901 atacgcaagc tattatagac caacttggta tgttacaagt cttcatagtg ataccatcat
    45961 ttttattgat atttggaatt atactactta taatgaataa aaaattagta gaattatcaa
    46021 attaaaaatt ttttaaagtt aataaaatat acaataaaaa atcgaggcat tataatacct
    46081 cgatttttat tgtatctagt acaaactata tagctctagt gtaaactttt aaccattctc
    46141 tttcttcatc agttaagaaa ggtgatattt tatcataaac taacttatga taccagttta
    46201 aataatcttt ttcatcctta ttcattaatt ctggtactat accatctaag tcaataggag
    46261 ctaacgtaac aacttcaaat tccataaatt gaccatagaa attcttttca gcttttctaa
    46321 ctacaatttc attctctgtt cttataccat gagaaccttc tatatatata cctggttcat
    46381 tagtagttac cattccttct tcaagaactg cactatcaaa tctttcaggt actactctcc
    46441 atctaaatcc atttggagct tcgtgaacat ttagcacaaa tcctatacca tgtccagttc
    46501 cacattgata atcaattccc atattccaca tgcaacttct agatagtatg tctaagttat
    46561 atcctctaca accatgcaag aacttagcct tagaaagatt tatcattcct cttgctacag
    46621 aagtaaagtg tagttttaat tcatcactta taggtcctaa aactgtagtc ctagttatat
    46681 cagtagttcc atcataatat tgtccacctg aatctactaa aaataatcct tctgcctcta
    46741 atttataatt tgactctgga gttgcactat agtgcatcat tgcagcatgc tctttatatg
    46801 cagcaattgt attgaaactt ggctcaaaga aaccttcttg ctctcttctt aagtcctcta
    46861 atttttgagt agcacttatt tcagtgattt ccatcttacc tacatttttc tttaaccagt
    46921 acataaattt agtgaaagcc acaccatctt ttacatgtga atttcttata ttttctaatt
    46981 ctacctcatt tttttgagct ttaaaaaaca ttactggatt gaactcatca actttctcaa
    47041 cttcacaagg tatattattg taaattgtat aactaagctt agttccatct aataaaactt
    47101 tttcagtttt gtctatattt tttacaaatt catacacatc attatatggc tttatttgaa
    47161 cattttcctt agctagttca tctaatattt cttcatttaa cttactttca tcaacaaata
    47221 aataaacttc ttttaaagtt attactgcat aagaaagtac aactggatta tatttaacat
    47281 ctccacctct tatattgaat aaccatgcta tatcatcaag agtagttatt acatgagtag
    47341 aagtaccttt ttcactcatt ttttctctta atctagctaa ttttgagcta aaactttctc
    47401 cacaatattt aacatctaat aaaaatgctt tactatctga taaagcaggt ctatctggcc
    47461 atataccatc tattaaatca tactgatatt ctatctttat acctttttta gataattttt
    47521 cagctaatgt agctccttct ctagcagata taactctacc atcaaatcct aaagttcctc
    47581 cttcaggaat atttttatat aaatattcat ctgtagttgg gcaaccttct tgtcccattt
    47641 tgaataattt tattgtactt ccttctaatt gagattctgc ctgtataaaa tatcttccat
    47701 cggtccataa cccagcttcg tctttagtca caataaccgt ccctgctgaa ccattaaacc
    47761 ctgatataaa ttctcttgat ttgaagtaat ctcctacata ttcactttgg tgattatcag
    47821 aagatggaat catataggca tctatatttt tttcttccat aaattttctt aatccactta
    47881 atctatcttt tatattcaca acaagacctc ctcgaaataa tagtttgaat aactaaatat
    47941 ataagtatgt aaagtttatt acataaatat tttttgtata atttatataa atcttataca
    48001 ctctaattat cacaattata attttaatta taatatctat ttgtgtaaag ctttttttca
    48061 taatcaaaga ggaaattaca tttaatttta tatttaaatg taacttcctt tatttgaagt
    48121 aattcatcta tttacaataa ttcgtcatga attatttttc ttttgttagt aaatccatag
    48181 ccattaatct tgttaataca tttcttattc ccaataatat taaaccaaat attattaaaa
    48241 ctgttgctat tcctccaaat atctgtaaaa aaccaagtgt ggctgtaaaa ccagcaatct
    48301 ttcctgataa taaacttgca aaaaaacttg ttagatacca ggctcccata gataatgtag
    48361 catacttagc tggagctaat ttattgaaca ttgcaagtcc tataggagat aagaataatt
    48421 cacctactgt tgtaaatata taagtcaata ctataaacaa tatactagcc tttaccattc
    48481 catctggacc attagctaat gtagcaaata ccataactat aaacccaaca cccattatta
    48541 tcattcctaa tcccatttta actggaatag agaaatcacc tcttttggta tgagataatt
    48601 taacccatag ggtagctaat actgggcata aagccacaca taatatagca tttagtgatg
    48661 taagccatgc tactggcatt tcaaatccaa atagagttct atttacatta tcccttacat
    48721 aaatcataaa agaactttgt gtttgatagt atgctgtcca gaataagacc acaaataaaa
    48781 ataaaataac cattgctatt atcctatttt tctccaactt agtaagtggt ccatactcaa
    48841 ttttttcacc tttattacct ttagtcacag gatattttcc gacttcattt aataattttg
    48901 gtgcaagaag tgtaaatata atcataccta acatcatgcc tataccacaa attaaaaatg
    48961 ccatcttata tccataagat actatatctc cacttgctcc tcttactgca aatacattat
    49021 cagaaagcaa tccacatatt attggagcta taaatgctcc tacatttact gccatataga
    49081 ataaactgta tgctgcatct tttcttgaca catcagtttt aggatatata tccccaacta
    49141 tatttgaaca acttgattta aaaaaaccat ttcctaaaat aattattgat agacctaccc
    49201 aaaccatggc aatagatgta gatgaagcaa atagtacgaa atctcctatt gctattaaaa
    49261 gtgcacctat agaaatacat ttttgttgac ctaaaacttt atctgctaac cagccaccga
    49321 ctaatggtgt aagatatata agacctgtaa ataagccaaa catggatgtt gcttcttgag
    49381 tagaaagacc taaaccacct tgagctacac ttgctgtaaa aaataatacc aataaagctg
    49441 ttaaaccata ataactaaat ctttcccaca aaattgtcat gcaaataagc caaaaactct
    49501 tcggatgacc acttttttta gatacgcttt ctgtacttga cataaaaaaa cgcccccttt
    49561 tgttttatag ttgaatttaa tattaatatt gctttaacca ttttagcaca tacttataat
    49621 atcatctttt ctatgtttac tcaatagatt atcgcctgta ttttcatttt tttattatta
    49681 tttttaaaat tatgaaaaat attatttttt tagtatcttc agtagaaaat cttaatatat
    49741 at
//
LOCUS       DAEQJM010000025        48974 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.025, whole genome shotgun sequence.
ACCESSION   DAEQJM010000025 DAEQJM010000000
VERSION     DAEQJM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48974
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.025"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            212..1429
                     /locus_tag="KRQ43_001763"
     CDS             212..1429
                     /locus_tag="KRQ43_001763"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HBH2742121.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1524..1904
                     /locus_tag="KRQ43_001764"
     CDS             1524..1904
                     /locus_tag="KRQ43_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH2742122.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2188..2670
                     /locus_tag="KRQ43_001765"
     CDS             2188..2670
                     /locus_tag="KRQ43_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH2742123.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVNLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2691..3506
                     /locus_tag="KRQ43_001766"
     CDS             2691..3506
                     /locus_tag="KRQ43_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH2742124.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3557..5107
                     /locus_tag="KRQ43_001767"
     CDS             3557..5107
                     /locus_tag="KRQ43_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH2742125.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5204..6556
                     /locus_tag="KRQ43_001768"
     CDS             5204..6556
                     /locus_tag="KRQ43_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH2742126.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAESLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKVFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6687..7445
                     /locus_tag="KRQ43_001769"
     CDS             6687..7445
                     /locus_tag="KRQ43_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2742127.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIYNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7492..8211
                     /locus_tag="KRQ43_001770"
     CDS             7492..8211
                     /locus_tag="KRQ43_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH2742128.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8335..9735)
                     /locus_tag="KRQ43_001771"
     CDS             complement(8335..9735)
                     /locus_tag="KRQ43_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBH2742129.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADIGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9739..10647)
                     /locus_tag="KRQ43_001772"
     CDS             complement(9739..10647)
                     /locus_tag="KRQ43_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2742130.1"
                     /translation="MKGDNKVTEKQRLIINIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10908..11555
                     /locus_tag="KRQ43_001773"
     CDS             10908..11555
                     /locus_tag="KRQ43_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH2742131.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11880..14519
                     /locus_tag="KRQ43_001774"
     CDS             11880..14519
                     /locus_tag="KRQ43_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH2742132.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14577..15680)
                     /locus_tag="KRQ43_001775"
     CDS             complement(14577..15680)
                     /locus_tag="KRQ43_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HBH2742133.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSSK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16041..16862
                     /locus_tag="KRQ43_001776"
     CDS             16041..16862
                     /locus_tag="KRQ43_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH2742134.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16941..17152
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17239..18555
                     /gene="argH"
                     /locus_tag="KRQ43_001777"
     CDS             17239..18555
                     /gene="argH"
                     /locus_tag="KRQ43_001777"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBH2742135.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVGLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18804..19142
                     /locus_tag="KRQ43_001778"
     CDS             18804..19142
                     /locus_tag="KRQ43_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HBH2742136.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19269..20558)
                     /locus_tag="KRQ43_001779"
     CDS             complement(19269..20558)
                     /locus_tag="KRQ43_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH2742137.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFFTGNNILMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20638..21342
                     /locus_tag="KRQ43_001780"
     CDS             20638..21342
                     /locus_tag="KRQ43_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HBH2742138.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21434..22480
                     /gene="selD"
                     /locus_tag="KRQ43_001781"
     CDS             21434..22480
                     /gene="selD"
                     /locus_tag="KRQ43_001781"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21482..21484,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBH2742139.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDNPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22498..23910
                     /locus_tag="KRQ43_001782"
     CDS             22498..23910
                     /locus_tag="KRQ43_001782"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBH2742140.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVAELRKAFN"
     gene            24024..25907
                     /gene="selB"
                     /locus_tag="KRQ43_001783"
     CDS             24024..25907
                     /gene="selB"
                     /locus_tag="KRQ43_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBH2742141.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALEALISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26012..28750
                     /locus_tag="KRQ43_001784"
     CDS             26012..28750
                     /locus_tag="KRQ43_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HBH2742142.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSIILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28869..29813)
                     /gene="manA"
                     /locus_tag="KRQ43_001785"
     CDS             complement(28869..29813)
                     /gene="manA"
                     /locus_tag="KRQ43_001785"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBH2742143.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            29986..31347
                     /locus_tag="KRQ43_001786"
     CDS             29986..31347
                     /locus_tag="KRQ43_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH2742144.1"
                     /translation="MELFKAESKKYEKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSIVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31435..33324
                     /locus_tag="KRQ43_001787"
     CDS             31435..33324
                     /locus_tag="KRQ43_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH2742145.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIYCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33339..33794
                     /locus_tag="KRQ43_001788"
     CDS             33339..33794
                     /locus_tag="KRQ43_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2742146.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33853..34170
                     /locus_tag="KRQ43_001789"
     CDS             33853..34170
                     /locus_tag="KRQ43_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH2742147.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34195..35457
                     /locus_tag="KRQ43_001790"
     CDS             34195..35457
                     /locus_tag="KRQ43_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH2742148.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFIDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35562..36626
                     /locus_tag="KRQ43_001791"
     CDS             35562..36626
                     /locus_tag="KRQ43_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH2742149.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKIGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKIIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36680..37858
                     /locus_tag="KRQ43_001792"
     CDS             36680..37858
                     /locus_tag="KRQ43_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBH2742150.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFVPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGKFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKNIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(38049..39107)
                     /locus_tag="KRQ43_001793"
     CDS             complement(38049..39107)
                     /locus_tag="KRQ43_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBH2742151.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTIFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINEIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39174..39545
                     /locus_tag="KRQ43_001794"
     CDS             39174..39545
                     /locus_tag="KRQ43_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBH2742152.1"
                     /translation="MKKKDILLILGILVVIIACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39582..40256
                     /locus_tag="KRQ43_001795"
     CDS             39582..40256
                     /locus_tag="KRQ43_001795"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBH2742153.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40505..41344
                     /locus_tag="KRQ43_001796"
     CDS             40505..41344
                     /locus_tag="KRQ43_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH2742154.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41587..41683
                     /locus_tag="KRQ43_001797"
     tRNA            41587..41683
                     /locus_tag="KRQ43_001797"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41621..41623,aa:Sec,seq:tca)
     gene            41834..42541
                     /locus_tag="KRQ43_001798"
     CDS             41834..42541
                     /locus_tag="KRQ43_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HBH2742155.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42683..43519)
                     /locus_tag="KRQ43_001799"
     CDS             complement(42683..43519)
                     /locus_tag="KRQ43_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2742156.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHIIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNVIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43707..44612
                     /locus_tag="KRQ43_001800"
     CDS             43707..44612
                     /locus_tag="KRQ43_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HBH2742157.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44621..45805
                     /locus_tag="KRQ43_001801"
     CDS             44621..45805
                     /locus_tag="KRQ43_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2742158.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     RIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNTYINE
                     YI"
     gene            45920..47221
                     /locus_tag="KRQ43_001802"
     CDS             45920..47221
                     /locus_tag="KRQ43_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HBH2742159.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTLIESIFFLLEKISNLSFAYINIESPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47175..48218
                     /gene="holA"
                     /locus_tag="KRQ43_001803"
     CDS             47175..48218
                     /gene="holA"
                     /locus_tag="KRQ43_001803"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBH2742160.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48405..48671)
                     /gene="rpsT"
                     /locus_tag="KRQ43_001804"
     CDS             complement(48405..48671)
                     /gene="rpsT"
                     /locus_tag="KRQ43_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBH2742161.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
BASE COUNT        19215 a         5283 c         8357 g        16119 t
ORIGIN      
        1 agaatgtaaa aaatattttt aaattatcat ttaatgtaat ttaaatgaat tgaagatata
       61 tgtttattgt atgcaattgt tgtattttta ggttttttgt gattaattaa aaaattataa
      121 aaatcgttta catgttgatt tttaaaaaaa aaagatatag aattatatag aaagtaataa
      181 acaaaaattg gatttacggg agtggaatga aatgatgaat gttaccttaa cagatgtgaa
      241 agaggctaga gagaccatta agaacatagt aaaaagaact gacttacttg aaagtgttaa
      301 acttagcgaa aaaacaggag caaatgtgtt ctataaatgt gagaatcttc aaaaaacagg
      361 ttcttttaaa ttaagaggag cttgtaacaa aatagcgagt ttaacagatg aagaaaaggc
      421 aaatggagtt atagcttcaa gtgcagggaa tcatgctcaa ggagttgcat tgggagcaaa
      481 aatgactggt ataaaatcta caatagtaat gccagcaact gcgcctttag caaaagttag
      541 tgcaactaaa ggttatggag cagaagtagt tttaaatggt gcggtttatg atgatgcata
      601 tgcaaaagct gttgaaatac aaaaagaaac aggagcaact ttcttacatc cattcaatga
      661 taagtatgtt atagcaggac aaggaactat atctcttgaa attttcgaac aattagacaa
      721 taaagttgat actatactat gcccagttgg tggaggagga atcatctctg gtgttgctgt
      781 tgcagcaaaa gcattaaatc ctaatgtaaa aatagtcggt gttcaaactg caaatatacc
      841 ttcaatgaaa gagtcaataa aaaatggaaa agtaacaaca gcatttaatg atactacaat
      901 agctgatggt atagctgtta aaactccagg agatttaact tttgaaataa taaatgaatt
      961 ggttgatgaa atagtagtgg ttgaagagac agaaattgca gaatcaatat tatttatgat
     1021 ggaaagtcaa aaaatagttt cagaaggtgc tggtgctgta tgtacagctg ctatattaag
     1081 tggtaagtat gtaccagcaa aagatgaaaa tgtagtttgt ataatatctg gtggtaatat
     1141 agacataaat acgttatata gaataatagg tgttgcttta gctaaagaag gaagaagata
     1201 ttcatttagt acaattatgg aagataagcc aggaaacttt gctgagttaa ctagaataat
     1261 aagtgagaat ggtggaaaca ttttaagtgc taatcaaggt aaattatcag caggggaagc
     1321 tctaggaaaa caaagtgcgg aatttatatt agagacaata gattatgacc atatagctag
     1381 aataaagaaa gctatagaag aaaaaggttt taaaattata gaattataat aaaaagtgta
     1441 tataatatac aagaaaaata gtataatagt gtatgaagat acattttatg tgtattagat
     1501 taacgaatta ggaggatttt aaaatgaaac atgaagtaat acatactaat gatgcaccag
     1561 cagctttagg accatattct caagctataa aagctggaaa cttattattt gtatctggac
     1621 aagttcctct tgtaccagag actatggaag tagttgaagg agatgtacaa gctcaaactg
     1681 ctcaatcttt aaaaaatctt aaagctatat tagctgaaag tggagctgat ttttcaaatg
     1741 tagttaagac tacagtattt ataaaagata tgaatgaatt tggggctata aacgaagttt
     1801 atgctgaata ttttggagaa aataaaccag caagagcttg tgtagaagtt gctagattac
     1861 caaaagacgt taaagttgaa atagaagtaa tagctgtatt ataaaaatac aatattttta
     1921 atttgaaaag gctgaaaaac tatattctag tgattcagtc tttttataaa aaaataaatc
     1981 acaataaaga acatgataaa tattgtcgaa ttaaaaaata aaattaaaat aaatattgca
     2041 atatttttga gaaggtttta taatgagtat ataatttgaa acgtgtaact attaaattag
     2101 gcatgagttc ttggatattt ttatcctgag gattcatgcc ttttttgtat tgaaattcaa
     2161 aaatctattt aataaggagg aagtattgtg ttaaattttt tcaagaaaaa taaaagctat
     2221 aagttacatg cagtagtgag tggtaacagc attaatattg agaaagtaaa cgattctgtg
     2281 ttttcaaaaa agttaatggg agatggagtt gcaattattc ctaatagtaa tgttgttgta
     2341 gccccttgta atggtaaagt aactgtgctt acagaatcaa agcatgcctt tggtatggtc
     2401 tcagatgagg gtgttgaaat attagtccac ataggaattg atacagttaa tttacagggt
     2461 gaggggttta aaaatgaagt gtctcaagga gatactgtta aaaaaggtag tccaataata
     2521 agttttgaaa gagaaaaaat aaattctcag ggaattgatt gtacaacaat aataattgta
     2581 ttaaatcata gcgaattttc agaaataaat tgcatggtag aaaatgaagt tgttgcaggg
     2641 caagatactg ttattgaaat tatgaaataa taggaaggga ttaattcaat atgagagtag
     2701 taaaaatctt taataataat gcattatcta cagtaactaa tgataggaaa gaagctattt
     2761 tactaggtct tggtataggt tttaataaac gtccaggaga taaagttaat gaagataaaa
     2821 tagaaaagat ttattatgtt caagaccaca tgcaaacaaa atttttagaa ttattaaaaa
     2881 atgttagtcc agaagtgatg gatgcttcac aacaaattat aagtcttata ccaggaaatg
     2941 agggaaaatt taataataaa gggatattat ctttagtgga acatattagt tttgcaatag
     3001 atagaatgaa aaataatgtt tttttaccta atttaatgct tttggatata aagatgatgt
     3061 attcaaaaga gtttgaatta ggagtaaaag ctttagaaat tatatataga gtatgtcata
     3121 tccatttgcc tgaagatgaa gcaggttaca tagctttaca ttttgtcaat ttacaatcaa
     3181 atgataattt ggcatatgat actttaaaat ttgtaaaagg tagtattgat ttgattaaag
     3241 aatgttatgg attagaatta gacgaatcga gtttaagtac attacgtttt agaactcatc
     3301 ttaaatttct tgctcaaaga atttttaaga atgaaatttg tcaggatgat aaaatgattg
     3361 aaatgtatga ttatttaatt aacaatcatc ctaaaaataa agaatattta gaaaagttaa
     3421 atgtatatat tgaaaaggag tttaggtata aattagataa acctgaaaaa atttatctac
     3481 tactacacct aacaaaaatc ttataagaat gagatgaatt agtaatagaa atatataatt
     3541 ttaggggggg ataagattga aagaaaaact acttggagga ctggaaacat ttgcaaaggc
     3601 aatggttcag ccattaatgt atttatcgag tgcaggaata ttaatggtgg taggtgtact
     3661 acttacaaat gatatgttat taggagtact tccatttttt aaatgggagc caattcaaat
     3721 atttggaagc ctaatttata actgtataat ggctattatt aataatcttg ctgttatatt
     3781 tgctataggt attcctgctg cactagcaaa aaaagagaag cacaaagcag cgttaatagg
     3841 atttatgagt tatataatat accttacagc ttccaacact atgttaacat cactaggtca
     3901 actagcaaaa gaaagcaaga tgcttggact gatagggact ggacaagcta ctattttagg
     3961 tattcaagtt gtagatacaa gtgtatttgg tggaattatt ttagggtgta tagctggata
     4021 tgtatttaat cgtacaagca acaaaacatt taaaggagct ttacagatat actcgggagc
     4081 aaattttagt tttatatgca tgttctttgt atccatttta attggagttg tgagtaactt
     4141 tatatggcca ttagctcaac aaggaatagc ttctcttgca aatgtcatca aagatacagg
     4201 tacatttggt ttattcttat atggtttttt agagagaata ttagtaccaa ctggacttca
     4261 tcatttaatc tatacaccat ttcagttttc tgatttagga ggagtgctta aagttggtgc
     4321 agatacagtt tcaggagcct atgctatagt tatgacagaa atgaatttac cagttgagcg
     4381 tttctcagat agtatatact acatggcaac tggatttaca aagatgtttg gttatatagg
     4441 tataggagct gcctttattt atactgcata taagcaaaat aagaagaaag ttaaggcaac
     4501 gattattcca ctaataatta cggcagtatt agcctctgta acagaaccat tagactttat
     4561 gtttgtattc tgtgcaccac ttttattctt tgtacatgca gttatagctg gtctttttat
     4621 agctttatta aaaatatttg atgttactgc attatgtgga gggaacttat tagtatcaat
     4681 tataatgaat actacagtag gtgtagaaaa aacacactgg ccagtaatga tgatattagg
     4741 acttgcacaa attattgtat attttgtagt atttagtttt ttaattaaga aatttaatta
     4801 taaaactcca ggtcgtgaag atgagagtac agctacaggc gaagaacaat caaaacaact
     4861 taatttagat gcaggtatag aaaatataat tgatgggtta ggcggaaaag aaaatattaa
     4921 tacagtagaa aattgcatca ctagattacg tgttaatgta aaagatgaaa gtaagattaa
     4981 tgaagatata attaatttaa cgccaaatag cgggattgta aggaaaggaa aagatataca
     5041 aataattttt ggacttcatg tgcatgaggt aagacgtgca gtagaagatt ttttagaagc
     5101 ttattaaaga tatatattta tatagcaagg gtaaataaca gctttaagtg ctgtttacta
     5161 tttattaaag atacatataa tttatagagg aggaataatt attatgatta ttactattgt
     5221 tggtggagga agcacattta ctccaggtat tgttaagtca attgcgttaa gagaaaaaga
     5281 gttagagctt gaggaaattc gcttatttga cattgataaa gaacgccaag ataaagtagc
     5341 tgtagttgtc aactggatac taaaagaaga tgttaaaaca gatgttaaac taactgtaac
     5401 taattgtgaa aaagaagcgt atacagatgc tacatttata tttgcacaaa tgcgtgttgg
     5461 taaatatgaa atgcgtgagc aggatgaaaa aattccattg aaatatggtt gtgtaggtca
     5521 agaaacttgt ggttgtggag ggatggcata cggactgcgt acaatacaac caatgataaa
     5581 ggttattgat gatgtagaga aatatgctaa aaaagattat tggatattaa attactctaa
     5641 tcctgctgca atcgtttctg aagcttgtcg taagttaaga ccaaatgcaa ggattataaa
     5701 tatctgtgat atgccaatag ctattataga tatgatagcg gagtcattaa atatcaatga
     5761 cgttcataat atacgctatg attattttgg tctaaatcat tttggctggt ttacttcaat
     5821 agattataaa catagagact taatggaaga gattaaggaa tacataaaag aaaataaaat
     5881 attattacca aaatcttata tagaaaactt aaataaaagt cgtagtacag gaaatcgcca
     5941 tgctgtaagt agctggatac atgtttggga atctgtttat acaatgttag aaagcttccc
     6001 aaaatatctg ccaaacactt atttaacata ctatctttta agtaaagaaa cagtggaaca
     6061 ttcaaacata aatcgtactc gtgcaaatga ggttatggaa agccgtgaaa aagacttatt
     6121 tgaaggtgtg agacattact tagaaactgg agaaatttct gaaaaagtat tttatgcagg
     6181 ttcacatgga gattggatta gtgatttggc agtttcaatt aaaaatgata cacgtagtcg
     6241 ttttttagtt ataactgaaa atcgtggagc tataccaaac atgccatatg atgcaatggt
     6301 agaaattcca gcatatattg gtaaagatgg tccagaagtt attgctcgag gtccaatacc
     6361 tctattccaa caaggattaa tgatgcaaca acttaacagt gaaaaattga tagtagaagc
     6421 ttatatagaa aatagttatg aaaaagcttt acaagcattc acattaaata aaactattcc
     6481 aagtatgaat gttgctaaag aaattttgga tgaaatgata gaagttaata aggaatactg
     6541 gccagaatta agatagtagg ataaaagaaa gggtttttat ttaataatta gatatgtttt
     6601 cagagtcttt tatcaaaatg tattcacaaa catatggcaa tatattaaaa taaagagtga
     6661 tatttttaga agaatggggt gatgcaatga acattataaa taaaattttt tggcaagaag
     6721 ataggattgg catgattaca aataatttag aggcagatac acatagccac tgcatgttac
     6781 aactgttctt agggatagaa gacagcattg aaataacagt caatgaaaaa ttagttaaat
     6841 gtaattgtat catagtagat aaaaatatct ctcattcatt ttcagcaaga aaaaaagttt
     6901 attactctgc tattattgaa cctacatcta tatatgcaga acagcttacc tcaaaaatga
     6961 atgattttgg ctactggata tgtgacaatg atggattaga gaaattacgt caacaaggaa
     7021 cttttttgat atataactct agtaaagaac aatatttaag atttatggaa atgcttaata
     7081 actatttgaa tatacctata actctcaaac attatgatga cagaattact gaattgctca
     7141 atttattacg tacttgtaat tgtgataatc atactatttc aagttttgca gataaagtgt
     7201 ccctatcagc aagtagatta tcacatctgt ttaaagaaca aatagggata cctttaaaaa
     7261 gctatatctt atttcatcaa atggagtgtg cttttagaga attactttct gggaaaaatg
     7321 ttaccgaagc ttctatgact gctggattcg atactccatc acactttgca gggacagtta
     7381 agcgaatgat gggaatgcct gtttctttat ctttgaaaga tagcgaattt ttgaaagtat
     7441 attaaatatt ctcgttatat aatgaagttg tactaagaaa ggggctttgt tatgaataaa
     7501 gaatatttag aggaaacaaa aatgttaaat tataatgaac cacaacttaa gcttttggta
     7561 tcatcaaaga attggttgga attagatgat tttcataaaa taaaatctat ttatgagttt
     7621 gtacagaatg atattttatt tggatataat gcttctgata tgttaagcgc aacacaggta
     7681 ttaaatgatg gtatgggaca atgcaataca aaagctactc ttttaatggc attattacgt
     7741 gcagtgaata tcccttgtag gcttcatgct tttgatgtaa caaaagattt tcaacgaggt
     7801 gctacatcca aattgatttc actattagca ccaaaatata ttcttcatac ttgggtagag
     7861 gtattttatc aagataggtg gattgctctg gagggtgtca taactgataa aaaatattta
     7921 gaagcaattc agaagaagtt ttttaatcat ggtggaacgt ttaaaaagta tgcaatagct
     7981 acaaatgatt tgaaaaatac atctattgat tgggatggta aagatacttt tatccaaaaa
     8041 gaagctatcg tgtatgatta tggtattttt ccatcaccag atgtattttt ttctactcat
     8101 tcacaacata tgtcaaaatt aaaaaatttc atatatgtac atcttatcag aaaaataatg
     8161 acaaaaaatg tatgtaaggc tagaaacaat tatattgata aaaacgaatg agtgtttaag
     8221 aggtaactat ataggaaata tatagaataa ttaaaactgt actggttaaa atgaataaaa
     8281 aggagttatc atagagcaaa cttaaattgt tcataggata actccttttc tgtattaact
     8341 tctaataatt tgatgtcttt ttataaaaca tatagataca attaaaccag taaatgcaag
     8401 agtagctgct attgaaaatg caacatctat tccatgaatg ttagacagca tgtttgaact
     8461 catatgagct ttcttagtag cacttgtcat tatagtaata agtatagcag aacctatagc
     8521 tccagatatc tgacggagtg tgttattaat tgctgtggca tgagatataa gttctctatc
     8581 taatgtttta attccccatg tagttaatgg cattaaaacc attgaaatac caatcatacg
     8641 aatacaatac atcaatgaca catgaattaa agatgtatct ctgcctaaaa aagcgaagga
     8701 taaagttcct aaaaacaaac atcctgttcc taatattgat agagcatgag gtccatattt
     8761 atctaaatga cgtcctgcaa ttggattgag tacaaccatc aatatagcac caggtaacat
     8821 taatgaacct gaagataatg cagaaaatcc tcttacagat tgaacgtaca gaggaatcat
     8881 taatgtagca gacatcattg aggcatatac aatcataatt aatattgtag aaataagaaa
     8941 tggtttattt ttaaaaaccc tcaattctaa aaaaggttct ttagatttta attgacgcaa
     9001 tgtaaataaa attaatgaca taattcctat taatattggt aaatatgtgg caatattagt
     9061 ccacccataa ttaccttgat tagtaaatcc aattaataaa ccaccaaaac ctagagatga
     9121 tagtactatt gaaggtatat ctaactttag tttttgagtt tccccaacat ttcttaatag
     9181 aataaatgat agtataacat ctaatatagc aataggggaa agaaacagaa ataaactatg
     9241 ccaaccaaat gaatctacta accatcctga taaagttgga cctattgctg gagcaaatcc
     9301 tactgtaata ccaactaaac tcatagctgc accacgtttt tcctcagggc ataaatagag
     9361 tataataact tgtaaaagtg gcattagaga accagaaccc attgcctgca acacacgagc
     9421 aatcaacata gttgaaaaat tattagaaaa aagtgcaata atacatccta tagaaaagat
     9481 agacattgat gtaataaata actttctagt actaaatcga tttattaaat aagctgttgt
     9541 gggtacaata atacctgcaa taagtagata aattgttgtt aaccactgac caatatcagc
     9601 agtaatttta aaatctgaca ttatattagg taatgctgtt gacaatagtg tttgactgag
     9661 agaacttata aaagcaccag tcattacaat tgctattatt aaatttcctt ttttattgtt
     9721 actttgggtt tccataattt ataacgtctc cttttttaat tgatttttaa tgctgttcaa
     9781 taaaagtact tttggtctta aagtgtcttc tttttctaaa tatgcaatca ttgcatccat
     9841 aattaaagaa tcatattgtt gattttttcc ctcgacgtat aattttttta ttgcttctag
     9901 taatttagga ttttcaagga gagaagtatc agttttgatt agttcttcta tatcttgtat
     9961 cgttttaaaa aatagcgatt tattatgaag ggaaaagtaa acttcatctt cttgtttatg
    10021 taaaaacatt gatttttcaa ttaaaggatt tagattatcc atattttcta caactaaatc
    10081 tagaatttgt atagtaaatt tggcaataaa gtatacattt atttctcttt tttgtacatg
    10141 aataatgtat ataaactgat gaattagagc atccaataag aaaactaaat caaatataat
    10201 tttttctatt ttatcaccat agttatcaaa taagcttaat ttgtattcat tcaataagtt
    10261 agctcgtgat tttgtttgca atttacttgt agccttacgt tgctcttcag aaaaattttc
    10321 tcttatatag gtatttatgg tagttctaga aaaaatattt ttccatacag caattatctt
    10381 tctgtttaac ttttctgatg atggaatgtc attattttcg tttatggaat gtataatttc
    10441 taaaaacttt tcatcataat aattgattat ttcgcagata aaactttcct tagtttcaaa
    10501 atgcttgtaa aaagtagctt tagacatttt acactctttt acaacatccg atattgaagt
    10561 attttgaaaa cctttttggt caaaaatttt ttgtgcaata tttataatga gcctttgttt
    10621 ttctgtcact ttattatctc ctttcacgca aaaacgttta gtactatata gtacctacaa
    10681 gttttaataa atatattata catcatttgg aaaaaaaatc aatatataga ctgtaatatg
    10741 aaatttttga aaaatttgtt gttattttta gtcgtataaa aaagaaactt aagagtttct
    10801 taagaattgt ttaaagaagt tgcaataaat tagtggtatg attatagtat gaaagagaat
    10861 gtcttgaaat ttttctgtat caaattccaa ttatggaggt gtagtatatg aaaaagaaaa
    10921 tttgtgtagc aataattttt gctctattta tagtttttgt agaaatgttt attgatagct
    10981 ctagcgaagg aagtaaaatt atgacagctg aattaagtaa atacaggaaa ggcgtaaatg
    11041 tattatcaat aaacaatatt atagtagcga ataaaaaata tagtttgccc aaagattatt
    11101 ctcctcagga aagcagtgaa gcgagagatg ctttttataa aatgaataaa gatgctcaaa
    11161 agtcaggatt aaatttaaaa gcttttagta catatagaag ttatgaatat caagatagat
    11221 tatttaaatc atatgtaaaa gaacatggag aaaaagaagc aaatagattt tcagctaaac
    11281 ctggagagag tgagcatcaa actggacttg cttttgatat tggaggagat gaccagtctt
    11341 gttgggcaaa taaaaagttc aacaatacaa aagaagctaa gtggttgtat gaaaatgcat
    11401 ataaatatgg ttttatactt agatatccag aaggtaaaga gaatataaca ggatatatgt
    11461 atgaatcttg gcactataga tatgttggaa ctgaacatag caaaaacttt gcaatgaata
    11521 atttgacttt agaagaatat ttacatataa attaagagat ggtttgttaa aattaggtta
    11581 aaataaaaaa taacctagac tattagctgt gtaaagtgat ataatgtaaa tacaatttaa
    11641 gataactact cgaaggggag tagcttacac gaaagtggta attaatcgtc aagacagtag
    11701 aaatactcgg ttaattagca agggattcct tgatagcaag accttcaaaa taagcattag
    11761 gtatgtttgt tttggggtct ttttttattc aaggaatttt tatttaaaaa aatttaaatt
    11821 tcaagtatac ataagagccc ccaaacataa aataaattta ttgaagagga gggcaacaaa
    11881 tgtcttacaa aagtacttat caagaagtaa ttaaaaattt agactcaagt ttatctggtt
    11941 tgagtaaaga aagagcagaa gagttgttgg aaaaaaatgg agctaatgaa ttaaaagaag
    12001 cagataaggt tcctacttat aagcttttcc tagaaagttt taaagaccca ttagtaataa
    12061 ttctattgat agctgcttta gtacaaatat ttttaggtga aacagtggag tctataataa
    12121 tttttgcagt tattattata aactctgttc tgggtgttgt acaaacaaaa aaagcagaaa
    12181 gttcattaga aagtttgaaa aatttatctg caccaaacgc aaaggtaata agagacaata
    12241 aaaaaatgac aattccagca aaaaatctag tagttggaga tattgtattc ttagaagctg
    12301 gcgattacat accagcagat ggaaggctta tagaagcaca atctctcaag gttgtagaag
    12361 ggatgttaac tggagaatca gaaccagttt taaagcatac agaaaaaata agtgaagatg
    12421 taagtttagg tgaccagaaa aatatggtat ttagtggtgc tgtagttgtt tatggtagag
    12481 gttcttttgt agtgactgga acaggtatgg atactgagat gggtaaaata gctgggcttt
    12541 tagaaagtgc tgaaaataaa cttacaccat tgcaacaaaa aatagaggat tttagtaaaa
    12601 aacttggtgt aggtattgta atacttgctc ttttaatatt tataattcaa gtagcaagaa
    12661 attactttat ggctggaaat ggagaaatga cacaaattat tttagattca ttcatgttct
    12721 ctgtagcagt agcagtagca gctataccag aagctctatc atcaatagtc actatagtat
    12781 tggctgttgg aacaaatagt atggcaaaaa aacaagccat aataagaaaa ttaccagcag
    12841 tagaaacttt aggttcaaca agtgtaatat gtactgataa aacaggtact cttacacaaa
    12901 ataaaatgac agtagttgat tattatatgt atggaactaa taatgatgag ttagataaag
    12961 aaaaagtaaa ctattcttat catgctaaat tattgactat ggtttctaca ttgtgtaatg
    13021 actctcatat aactagtgat ggtaaagaag ttggtgaccc aacagaagtg gctttaataa
    13081 attattcaag taaaaatgat ttagattatg ataaattaag aagtaagtat atcagaataa
    13141 atgaaatacc atttgattca gacagaaagc ttatgtctac tgtaaatagt atatatggag
    13201 attatataat gtttacaaaa ggtgctccag atattgtgtt tagtagatgt aaatatgctt
    13261 tgaaaaatgg ttcaaaagta gatataacag atgagataat agaagaatat aaacataaaa
    13321 atgaagagtt ttcaaataga gcacttagag tattagcttt tgcaataaaa gatgtcccag
    13381 aagaagattt tataccttca attgatgacg aacatgacat gacattggtt ggaataatgg
    13441 caatgataga cccaccaaga gaagaagtaa tggatgcagt aaaagaggca aagagtgctg
    13501 gtataaaaac tgttatgata actggtgacc ataaaacaac agcagcagca attgcaaaag
    13561 agattggtat aatggaagaa ggagacttgg ctcttactgg aaaagagctt gatgctttga
    13621 gtgaagaaca actatatgaa aaactagaaa atataagtgt atatgccaga gtctcgccag
    13681 aaaataaaat tcgtatagta aaagcatggc aacataagaa taatataaca gcaatgactg
    13741 gtgatggtgt taatgatgca cctgcattaa aacaagcaga tataggaatt ggtatgggaa
    13801 gtggtactga tgtagcaaaa gatgcttctg ctatggtatt ggttgatgat aactttgcaa
    13861 gtatagtaaa tgctgttgaa gttggtagaa cagtatacag taatataata aaatcaatta
    13921 cttatctatt tgcaggaaac ttaggagcta tagtatccat agtatttgca gtgtttgcag
    13981 gttggtcaaa tccatttaca gctttacaac ttttgtttat aaacttagta aatgactctt
    14041 taccagcaat tgcattaggg tttgaaaagt cagaaaaaaa tataatgaat aaacctccta
    14101 gacacccgga tgaaagtata ctagcaggag gaacattgaa ggcagttgct ataagaggtt
    14161 gtataatagg tgtagttaca ataattgcac aatatatagg attacaagta tctccagaac
    14221 ttggagtagc aatggcattt tcaacattga tattagctag aataatgcaa acattacctg
    14281 cacgttctaa taatcaaaca gtaataaaat taggtttttt cagcaataaa tacgttatag
    14341 gagcagtttt agtctgtctt gggctttact ctttaacact aataccagtg ctaagaggaa
    14401 tattctctat accaacaacg tttggattgt accagttggg gatttgccta gggttagcat
    14461 taatttcatc aatattaatg gaacttaaca aattaataaa tagaagtgaa gtaaaataat
    14521 caaaaaatta aagggcatat tgattttaac aatatgcctt ttataaatag tctaatttat
    14581 tctatattat cgattatttg gaatgctttt ataacttcag gtaattcttt ttcttcaggc
    14641 attctaaatc ttatgaaatt tttatcaagt ccagtaaaat cacttccaga tataactctt
    14701 atttttaatt tagcaaactc ttgttgtaaa tctatgtcct tgtttttatg ttcaactgtc
    14761 ataattgata cagtatcact agtttcagct atattaaggt ttttccatgg aattagtaat
    14821 tgatttttta tatcttttgt tttttctttt aattcttcta taaattgaac atcatctaat
    14881 aaatttgctg caatactacg agatatttca gacacttcgt aaggagtaga aatcttttta
    14941 atagggctaa caagttgttc tggaagaact gcatatcctg ctcttagtcc tgctaaacca
    15001 aatccttttg aaaatgtttt taaagcaatt acattatcat aattatttag aagcttgaca
    15061 gctgaatttt cttttggcat gtattcacca taagcttcat ctaccataac tgctatatca
    15121 tatttagctg cttcctttac tatattttca attgatgata aaggtataat ttgtcctgta
    15181 ggattgtttg gattgtctat gtaaattact ttatattctg gatttatttt ttcaataaat
    15241 tctttttcat taaacttgaa attatcctct ttctttaaaa gaacataatc ataagttgca
    15301 ccatgcattt ttatatctgt ctcatattct gagaactgag gtgaatatcc taaaacttta
    15361 tctccctttt caataaatag tctatttaaa aggtaaataa catgtataga accatctgcc
    15421 aaacaaattc tgtcagtatc taatgctata aaatctttcc aataatcgac tatattatct
    15481 tttaaagcaa ttgaatgagg atatcctctt atcatatcaa attttaaagc attaaaagct
    15541 tctacagctt tgcttgagta agacacggta tttatacctt caccacagtc tatctcgaat
    15601 acatcttctg aatgtccaga ttctattgca taactttttt tcaactgcat ttcaatagct
    15661 ttgttaattt ttagtttcat actttatcac tccttattta gtcaataata aatgttataa
    15721 aagttgctag atttaaaata ttatgaaaat atataatagt aaaaaatgaa tataaatatt
    15781 ataatagctc actttattta atatgattat atatcatata ttgtaaaatt tctagcatta
    15841 taagactata aattgaaaat attcagaaaa atactacaag aaacgattta ttttgctctt
    15901 aaaataagtt aaatgaatgt tattaatttt gtaaattgaa atagtttaag tataaagtta
    15961 tgatataatc taataagggt aattctttag attatattaa ggaaatatag gtatacaata
    16021 aaaagttatg gagttggatt atgggatata aattaattgt aacagatatg gatggaactt
    16081 tattaggcaa taatcataaa gttacagatg aaaataaaac tgcactacaa aaagttataa
    16141 aaagcggtat taatgtaact ttagcaacag gaagagcctt cgattcagct aaatgcaatg
    16201 tagattttct taaagaggac atgccaataa tagcttgtaa tggttcatta ataagagagc
    16261 aaaatggaaa tataatatat tcaaataaga ttgatacaag aacatgttta aacattttag
    16321 atgtattaga taaatacgat atttactacc aatgtaatag tatagattct atgctttcga
    16381 aaaaaataga aggacgtgaa gatagattaa gtgtattttt aggctctgaa acagaagtaa
    16441 ttgtaaaaga tgatttgaga gaagaaatct ttaaaaaaga tatactaaaa tttgtaatca
    16501 tagaagaaaa aaatccatct attttggatg aaataagaaa agaattgaga aaagttcaag
    16561 gaataaagat aacttcttca tggccaaaca atattgaagt catgaatgaa ggtgttgata
    16621 aaggtaatgc agttaaaatt ttagctgaaa aaatgaatat agacagagaa gatataattg
    16681 catttggaga caattacaat gacatagaaa tgataaagtt tgctggtctt ggggtagcta
    16741 tgggaaatgc agaagaattg attaaacaag aagctgatta tgttacagat acaaatcaag
    16801 acagtggagt tgcaaaggca atttataaat tcctagagtt aaaagaatca cttagctctt
    16861 aaaacagtat ataataggaa aaaataggtt gactattttg tagatagtaa ttataataca
    16921 aatagataaa acataaaaat ttagattcag tgaaaaagag agtagatata gagaaaatct
    16981 cagcgaattg ggggatggtg tgagcctaat gataacactt tatattgaaa agaactttgg
    17041 agaatactac ttgaaattca gtatggtagt aggtaatctc gccttaagag aatagagtgg
    17101 gtaaacattg tttaccaact agagtggtaa cacggaatat ttcgtctctt ggtctttttg
    17161 accaagagat tttttagttt cattgagtta caagacttat aattaaaata caaaaaatta
    17221 aaatatgagg tgaaagttat gaaattatgg ggcggacgct ttagaaaagc ggaaaatcaa
    17281 cttatggaag aatttaataa atcttttggc tatgattgtg tactgtacaa aaaagatatc
    17341 gaaggaagtg tagcacatgt tcatatgcaa gtaaaatgtg gacttttaac agaagaagaa
    17401 ggaaagtcta taacagaagg tttaaaaggg atacttgaag atgtagaaaa tggaaagtta
    17461 gtattggatg gagagtatga agatatacat agttttactg agataaattt aattcaaaga
    17521 attggagatg ttggcaagaa gcttcataca gcacgtagta gaaatgacca agttgcagtt
    17581 gatatgagat tgtatgctaa agaaaaagca aatgatttgg tgggtttaat atctgaattt
    17641 aaagctacta taaaagatgt tgctgacaaa aacccagtga tgatgccagg ctatactcat
    17701 cttcaaagag ctcaagtagt gacatttaag catcacttaa tggcatatta tagtatgttt
    17761 gatagagatg agaaaagaat aaaaaatgct atagaaatat tagatgaatc acctttaggc
    17821 tgtggagctt tagcaggaac tacgcatgat atagatagaa gtataacttg tgaacaatta
    17881 ggatttaaaa aagtagtaga taattttatg gatggagtaa gtgatagaga ttatttacta
    17941 gagctaatga gtgatttttc aattataatg atgcacttaa gtagattaag tgaagagttg
    18001 atactttgga gttctcaaga atttggattt gttgagatag atgatttata tacaactgga
    18061 agtagtataa tgcctcagaa gaaaaatcca gatggtgcag agcttataag aggtaagact
    18121 ggcagagtat atggaaactt atttggtctt tttacagtaa tgaaaggaat accattagca
    18181 tataataaag acatgcaaga agataaagaa ggttttttcg atagtgtaca tactcttgaa
    18241 atgtgtatac aaataatgga tagaatgata gccacactaa aggtaaatga ggataaaatg
    18301 aaacaagcag taaaaaatgg ttttttaaat gcaacagaag ttgcggatta tttggttaaa
    18361 aataatgttg cttttagaga tgcacatggt atagtaggaa gtatcgttat atattgtgaa
    18421 gataataaaa aagcaataga agatttaaca ttagaagaat tacataagtt ttcagatgct
    18481 tttaaggaag atatttatga ttttatcgac tatgagagta tattaaataa gggaataaaa
    18541 aagaatttaa aataatgtat ttatttttaa aagctgtaaa tttgaatgtt atcatttaaa
    18601 tttacagctt tttattgtgt aagattttat tatataaaag taagaaactt aaaaggagta
    18661 gtatttaaaa taaatacaaa taaaaaatta ttattaaaat gataattaat atcaataagt
    18721 attgacaaaa ttatttctaa atactattat atataatata aataataatg aaaatcaata
    18781 tcaaataaat gggaggaaat ctaatgaact tattagtgat tggtggtcat gaaagaatgg
    18841 aaaaagatta tatggttatg gccaagaaaa aaggttataa gacaaaggta tatactacca
    18901 tgtcatctaa attaaataat tctataggaa gaccagatgc agttgtcata cttacatcaa
    18961 ctgtttcaca taagatgtct agaacggttg agtctcaagc taaaaaacaa gatatattaa
    19021 tcgtaaggca taaaaatagt agtaaggtag catttaatga atgtctagat atggttgatg
    19081 aatgtctggg aaattgttca aaatgtaagc ttaaagacaa acaaaaacaa aaaaatatat
    19141 aggtataaaa aatacataaa cataaaatta aaagtactga gataatagtt ataattatta
    19201 tctcagtact tttagattta taaggataag tatattataa attttttatt ataatttcca
    19261 actacttgtt actttttcat atttttttta cttctagctt tttttctttt tttcttcttt
    19321 atatttgaag ctattataaa taaaactaaa agcactagaa tacctgcaat aatcttaaca
    19381 aaagtcatta aaatattatt tccagtaaaa aatggaagac tgctatcaag attatttttt
    19441 gcaattaagt ctatactgtt ttctagttta ccattattat atacatttaa agtaccaacc
    19501 ttagctcctt tttttatagg caaatcaatt ttatttaact ctgttttggt atcataattg
    19561 ccttgagatt catctttttc taagaatatc ctataactat tttttggttc ataaatcaat
    19621 tcatgttgtt ttgtaaacaa tactttttta gtatctgtgt atttttcttt atcaacaata
    19681 gtagcacact taaagttatc aaatccataa tcaatcagaa tacgtgagtc taaatataaa
    19741 tcagcattag ttgaattaaa tacagcaacg ataactcttc tgccatcttt tacagcactc
    19801 gataaaagac atttaccagc agcatcagta tatccagttt ttataccatc aactatatca
    19861 tattttatat ttataggttg acctttgtat gtaatcttat catgtgatgt caaaaactta
    19921 ttagtgttta caaagtatct ctcataagga tatgcttttg tagcttcaaa tttaagtgac
    19981 ttagttttta caatttgtct aaaagtatca ttattcatag cttctctagc tatgagagcc
    20041 atatcatgag ctgttgtgta gtgatttggg tctggtaatc catgaggatt attaaaatga
    20101 gtattagtag ctccaatttt ttttgcctca gagttcatga ggtcaataaa tttttgtaca
    20161 ttgccaccac caacatatct agccaataca aaagcagcat cattagcaga atgaaccaaa
    20221 agagcatcta gtaactgctt tacagtaaaa gattccccat tttttagata catactagag
    20281 ccatctattt gaggtaaatc tttaatttct attacttgat ttaaatcttt aacctccttt
    20341 agaactaaac aagctgtcca tactttagtt gttgaagctg gataaagctt agaatttcca
    20401 tccttattat atagtatttt gccagactca tagtccatta aaactgcatg tttagcaact
    20461 atagctggtt cattatctgc aaaagagata ttagagcttc ctaaaaatga agtaaatatc
    20521 aataaacaga ttaataaaag tgataaattt cttttcattg tgagcctcca aattttaaat
    20581 tcatctttta gtatagcata tatttgtcaa taattaaaag aaaggagtga ttaatatatg
    20641 aaaaaaaagg taaaatttat ttcgtttttt gttttattta ttttaataat atcatcaata
    20701 atcgtttata aatcgcttat tttcaaagat gatatttatg ttgtaagtaa aaaaaattta
    20761 cctaatgaaa aaacacatgt tgtagagaat gaaattaaag gtgaagataa taatcacaat
    20821 aaagtaacta aagacataga taaaaatttt caaaataata aaataactat atacataagt
    20881 ggagcagtaa atagacctgg aattgtaact atagagtcag acaagagact ttatgatgct
    20941 gtagaattac taggaggaac gacaaaagaa gcagatttaa atggagtcaa tctatcagta
    21001 agattagaag atgaacaaca ttacataata cctaaaatag gtgaagcaac atctgttaca
    21061 agtaatgatg attccaataa accaaatcag aagaatgagt caagaggtga gcctaaaaat
    21121 aaatccaata aaaatatatc taacgaatca aaagtaaata taaatgtagc gactatagaa
    21181 gagttagatt ctctacctgg ggttggagaa gctacagcca ataaaatttt acaacacaga
    21241 gaagaaaatg gacagtttag ttcaattgag gaaataaaaa atgtaaatgg tattggagat
    21301 aaaaagtatg aaaatataaa agatttaatt tgtgtagact aaaatataat acaaaactta
    21361 catatagata tgttattata aatatgtatg tatatgtgtg tacatgtgga aatttagtaa
    21421 aggaggcact tttatgaaaa aagaacaaaa aaaacttaca gagatgacaa cagcaggtgg
    21481 ttgagccgct aaaatagggc cagaggttct ggcatcagtt ttatctcaat tgcctaaaaa
    21541 tgataatata gaaaatttat tagtaggact agatacagca gatgatgctg cagtttataa
    21601 attaaatgat gatatggcac ttatccaaac tttagacttc tttacaccaa tggtagataa
    21661 cccatacgta tttggtcaaa ttgctgcatc aaattcacta tcagatgtat atgctatggg
    21721 aggcaaacct ttggttgcta tgaatattgt ttgttttcca tcatgccatg atatggatgt
    21781 acttgcggaa atattaaaag gtgggtttga taaagtgaaa gaaagtggag cacttttggt
    21841 tggagggcat actgtagatg acaaagagcc taaatatggt ctttcagttt ctgggattgt
    21901 aagtccaaat aaagttttat caaatgctac tgcaaaacct ggtgataagt taattataac
    21961 aaaaccaatt ggagtgggtg tattaaatac agccatgaaa gaaggtatgg tagaacaaca
    22021 tatagcagat aaagtaatag aaataatgat acatttaaat aaatatgcag caatgagttt
    22081 tgagaaattt gatgtaaatt cggttacaga tataactggt tttggtctac ttggtcatac
    22141 tttagaaatg gccaaagctt ctgaagtaag tattgaaatt gaatcaaaac atgtaccaat
    22201 tattgaaggt gcaatagaaa tggcacaaat gggaattata cctgctggta tgtataaaaa
    22261 tatgcattat gtatctaaag atgtagaagt tgtaggaaat atagaagttg cagttcaaga
    22321 tattttatac gacccacaaa catcaggagg gttgttaatt tcagtaaaag aagaacttgc
    22381 agaggaactt gtaaaagata tgaaattaaa tggagcaata gaagctaaaa ttataggttc
    22441 tgtagttcca aaaggggaaa aatatattac agttttataa aatattatag agaaagagtg
    22501 attgttttga gcaaaagaga attgtttgca atgttgcctt cagttgatga agtattaagt
    22561 gataatagaa ttgtagaaat aataaatgaa tatcctagaa gtttagtttt agaatctgtg
    22621 agagaagtaa tagatttaaa aagacaattt atattaagat taaaagaaga tgcatcaaac
    22681 tctgtaacaa tagagtttgg tgaaataata gaatctgcaa tagagagagt taagttaaat
    22741 tactcattat ctttaaaaaa agttataaat gcaactggta cagttattca tacaaattta
    22801 gggaggtctt tacttagtga agatataaaa gatgaattat ggtgtgctgc ttcaaggtat
    22861 tcaaacttag aatacgattt ggataatgga gaaagaggtt caagatactc tcatttaact
    22921 agtacaataa aaagacttac tggagcagaa gatgtactag ttgtaaataa taatgcagcg
    22981 gcagtacttc ttgtacttag cacaatggct aaaggaggag aagcaattgt atctcgtgga
    23041 gaattagttg aagtaggtgg ttcatttagg attccaagta taatggctct tagtggtgca
    23101 gaattagttg aagttggttc aactaataaa actcatttga aagattacaa ggaggccatt
    23161 acagaagata caaatgtatt gatgaaggtt catacaagta attatagaat aatgggattc
    23221 acagagagtg tttctataga agaattggtt aatttaggta aaaaatataa actacctgta
    23281 atagaagact taggaagtgg agtttttata gatttatcaa aatacggttt atcttatgaa
    23341 ccaactgtat tggattctat tcgacaaggt gcagatgtag taacttttag tggagataag
    23401 atgcttggag gtccacaagc aggtattata gttgggaaaa aagagtatat agaaaaaatg
    23461 aagaaaaatc aacttactag agcacttaga gttgataagc ttacaatatg tgctcttgaa
    23521 gcaacattga gaatgtattt agatgagaca aaagctatag aaaatatacc tactttaaaa
    23581 atgttgacat ataaaattga agaattagaa gtaaaagcaa ataaactatt tgaaaaaata
    23641 actgctttaa acttaaatgc aaacataaat atagaagatg gattttcaca agtgggagga
    23701 gggtctatgc ctcttgaaac tataagtaca aaggtaatat caataactcc tgaacatatg
    23761 aatgtttcat ctttagaaaa aaaactaaga cttagtgaag cacatataat agccagagtg
    23821 tatgataata aatatgtact agatgtaaga actatatttg atgatgaatt tgatgtaata
    23881 gttgcggaat tgagaaaagc atttaattaa ataaatttga gctaataaat attaaattta
    23941 gaagtataag tatgaagttt tgattaaaaa atagctacac acacttgtga ctttagtcat
    24001 agcaggttta gagggggcaa aaaatgaaaa atgtagtaat tggaacagca ggtcatattg
    24061 accacggaaa aactactctt ataaaagcat tgactggaag agagactgat acattagatg
    24121 aagaaaaaaa gagaggtatt tcaataaact taggatttac ttattttgat ttaccaaaca
    24181 atagaagagc tggaattgtt gatgtcccag gacacgaaaa attcataaaa aacatgttag
    24241 ctggagcatc aggaattgat atagttttac ttgttgtagc agcagatgaa ggggttatgc
    24301 cacagacagt tgagcattta gatattctaa gctttttaaa tatcaaaaat ggaatagtgg
    24361 ttctaactaa gtctgatact gtagatgatg aatttagaga gctagtaaaa gaagatattt
    24421 gtgaaaaaat aaaaggaact tttcttgaag atgctgaaat aattgaagtt gattctatat
    24481 ctaaaagagg tatagacact cttattgaaa aaatagataa aatgagtgat gatatagaag
    24541 ataaaaatga aaactctcca gcaagactta atatagacag agtattttca ataaaagggt
    24601 ttggtactgt aataacaggc actttaatag aaggaaagat aagtatagaa gatgatttag
    24661 ttatatatcc acaggtatta aaaacaaaaa taagaagtat acaagttcat ggagaaaata
    24721 aagatacagc ttatgcaggt caaagaacag caatcaatat atcaaatgta aaagtggatg
    24781 atataaaaag aggagatgtt ttagctgcac caaactcatt agaggaatca atgatgttag
    24841 atgtaaaatt atcattggta aatcatttag ataaaggatt aaagcactgg gatagattaa
    24901 gattgtatca tggaactaga gagatacttt gtagagcagt tccactagat aaagaattaa
    24961 ttgaaagtgg agaaagtggc tatgttcagt tgagacttga agaaagcata gtatctaaga
    25021 aaggtgatac gtttgtagtg agacgttatt ctccaatgga aactataggt ggaggtgtaa
    25081 taattgaccc atctcctaaa aaacataaga aatttgatga aaaagttata gaagcattaa
    25141 aaataaaaga aaaaggcgaa ctaaaagata taatagaaga gtacttaaaa aggaatttaa
    25201 aaaattatcc aaatataaaa gaaataatga gctatagtgg tgctcatgaa gaagatgtaa
    25261 aaagagcgct tgaagcactt atatcagaag ataaagtatt tattatagga aatatgtata
    25321 tgcatataaa tcaatacaat aaattaaaag aaaatacaat aaagctttta agtgagtacc
    25381 ataagaagta taggcttaga aaagggatac taaaagaaga agtaaggtct aagatagaga
    25441 gtaattttaa gactagggag atggatattt tattagaaaa attgtctaca gaaaatgcta
    25501 taaaaataga aaataatata gtatctctat tagattttga ggttatttta aatgataagc
    25561 aaaaagaaat agcaaaaaaa atagaaaaaa gattaaaatc atgtggagtt tcttctatac
    25621 tgacaataga tgaagtttct gaaggaaatc ataactatgc tgaagtattg gagtcaatga
    25681 taggtaataa agtagagaaa ttagatgatt tgtatataat ggacaaagat atttatgaaa
    25741 atgcaaagaa cattttgata aattatataa aagaaaataa agaaataaca ttaggagaat
    25801 acagagattt gattgattct agcagaaaga attgcatgat tatattggaa aacttcgata
    25861 gaaacaaaat aactaaaaga gtagaaaaca aaagaatttt gttttagcag aaaatgtctg
    25921 tttttgcttt aaggtataaa gaaggaatta taatgtcgag tatcgtataa ttaattagta
    25981 taaaatatta attaagagga agtgtaaagt attgaagaat ataatacctg atgtaaaacc
    26041 agatataaaa gaaagagaag acatgagcct tttatttata ataatgggct cagtactttt
    26101 attatttatt ataaaagata tagagaaata tgaaacttta ttacatgcca tatatacgat
    26161 atttttagta gctacaggag taattatatt taatactaca aaatttaaag tagattcatt
    26221 ttctacattt ttaggattaa tttttatagc tactggagta ttggagtgta tatatttatt
    26281 taattccttg gggattaaaa ctaagtctat aatggagatt aacatcacaa tatcagcaat
    26341 aacagattta tttcctatac tgggtgtata cttaagtttt aaatttgtta aggataacaa
    26401 acaaatttat tcaagtataa ttttatttat agcaactgct acattaacaa taacatcttt
    26461 attcataata tcaggaattt gtgactatct gggaaatggt aaatcacaat atgctttagg
    26521 agttataata tctatattca taataattat ttctatcatt agtggaattg aattaaattc
    26581 aagttcaaat aaaggtaaat gggaatatga tgaaaaaaag atttttaaca gaataatagt
    26641 aataataatt ttatcaagag ttccaaatct attgcatata gttattgata atagaaatgt
    26701 agagcggata ttatcacaga taataataaa tgtagcctta tattatttat ataattacat
    26761 agtatctaag aatattaaga aaacagcact ggaattgcat gatacgaatg aagaattaac
    26821 aaaaaaaacg gaaagtttaa aagaaaagaa taaaaaatta atctatgaga cagaaaagat
    26881 agaggaactt aagggaatac ttatgaaaag agaatctagg ctacaatcta cattagatgt
    26941 agcagtaaat agcatagtag tgtttagcaa agatggagaa attacatatg caaataagag
    27001 ctttagaaat acttttggag actataaaga acaagataaa ttgactgata aaataaaaaa
    27061 cttcaatgat ttgatagaaa gcattcatta tgtgtttgtt catgagaaga atgcagagaa
    27121 acttattagt acaagcgata ataaagttta tcaagctata tttgcacctt taattattgc
    27181 ttcacaaaca gaaggagtat tgtgtgtact agaagataag actaagaaaa aggagtacga
    27241 acgcaaactt attgaagcaa ataagagaag taaagatttt ttagaaagta ttggagatgg
    27301 catagtagtg cttgaaggta ataacaaaat atatgttaat aatgcatgta gggaaatttt
    27361 taaaaataat ttagagagta ttgatttttc attagtatgt aaaagtgaag aaagtataga
    27421 aaaaagatat gtaatagatg gtgaagtaaa gtatgtagag atgagttttt ctcagtatac
    27481 taatgctggt actaataaaa ctattattgt aatacgtgat acaacctctc gaaaaatatc
    27541 tcaaataaaa cttgaggaaa gtcaatcatc atattcaaga tttatagata tattacctga
    27601 tggcatatgc ttattaaaag aagatttaag tataaactat gcaaataagt cgtttttaga
    27661 tatgctagct tttacaaaca tagatgatat aaaagattct aatattaaac tattaatgaa
    27721 tgcgaatact gaagaaaaaa tgaaatttac ggataatatg gctaaagttt taaatgaaaa
    27781 tagaagtata cttttactgg aatatgaatt gataaatagt tatgatgata tagtagaagt
    27841 agaattaagt gcattacctt ttgctatata caatactaga tacataatgc ttattataaa
    27901 agatttagta cataagaaat attccgagca agcagaaaaa gaactgcttg aaagatttaa
    27961 aacagataaa atcaaaacgg agttttttgc aaatatgtct catgaattaa aaactccact
    28021 aaatgttata tctagttcaa atcaactggt agattctttc tatagaaatg aaaagataaa
    28081 agattacaat aacaatatta aatctcatgt ggatttagtt agacaaagtt cttataggct
    28141 tcaaagatta ataaataaca ttatagattt aacaaagatg gagtctgggt tctatacact
    28201 aaaacttgcg aaatacaata ttgtatctgt aatagaagac ttatttatga atatagaaga
    28261 gtatgcactt agaaaagaca taaaaattct ttttgataca gaccttgaag aaattaatgt
    28321 ttatatagac aaggttgaaa ttgagagaat tatgttgaat ctattgtcaa actgtattaa
    28381 gtttactgat aatggaggct ggatatatgt aagtattcat tataaaatag ataaagtaat
    28441 cataagtgta aaagacactg gagttggaat accacaagat aaattagaat tgatttttga
    28501 agaattttca caagttgata agactttatc cagaaatact gaaggaagtg gaatagggct
    28561 tgctatagtt aagaatctag taagtcttca tggtggagat atagaagtag taagtgaagt
    28621 gaataaaggc acagagttct taatttcact tccaatgaag ggatttagta gtgaacatta
    28681 cacagaagat aagagaatat ataatattca agaaaaaata aaaatagaat tttctgatat
    28741 atactattaa aaatgattat gagcaaaaat aaaataaaaa tactatttgt ttaaatattt
    28801 aagttgtaag aaataggcta tcataaggta aattattatg atagcctatt tttagctagg
    28861 ttttatatct atatgtgaga acatataatc tctaaattac cttcaaaact aaaatctcca
    28921 aagtcgtttg gcagtataaa atgcataccc ttttttaaat tatattctac agaattgtgt
    28981 ataagttttc catttccatc caacacactg tataaagaaa aaggtgtatt gtgtgtaaaa
    29041 ttacattttc caaaaacatc taatttataa acactaaaaa attcgtttga cacaaatgtt
    29101 gtgcatttaa agtctgatgt tgatacgatt ttatagtcag tatcgaaatt tatatgagga
    29161 acattcgtaa catctattga tttttgaaca tgaagttcac gcttattacc tgaattgtca
    29221 gttctatcat aatcatagac tctataagta gtatctgagt tttgttgagt ttctaaaatc
    29281 aatgttcctt tgcatatagc atgtatagta ccacttggaa catagaaaaa gtctcccttt
    29341 tttatattaa cctttctaag tagtttgtcc cattcattat tatttaccat atttacaaat
    29401 tctttatgag attttgcatt atgacctatt ataatttctg catcatcaga acaatctatt
    29461 acataccaac actctgtctt acctaactct ccattttcat ttttcttagc atattcatca
    29521 tttggatgga cttgaactga taaattatca tttgcatcca atatttttgt aagtaaagga
    29581 aacttatcac caggtgtgtt tccaaataat tctctatttt tattccacaa ttcagatagt
    29641 tttttacctt tatattttcc attttctatt aagcaatctc catttttatg agagcttata
    29701 gcccaacatt caccagttgt tggcgaatct atttcataat taaatttatc tttaagtgca
    29761 gtaccacccc atattctatc cataaaaata ggttttaaaa ataatggttc cataatcctg
    29821 ttcctcctat gatattaaat ttatcctaca aataattata tataaataga ttataaaatc
    29881 aatagtaaaa aagttttgtc ccttgaaatg acataaagta taaggagtta ttaaataaga
    29941 taaactatga tatataatat aaagttctaa attggagtga taattatgga gttgtttaag
    30001 gcagaaagca aaaaatatga aaaagaattt ttaaaattat tggagcaatg ggttagtata
    30061 ccttcatttt atgatagaaa aactgtatct aaagatatgc cttttggaaa aggagtatat
    30121 gatgcattaa actggtttga aaatctaggt agagaaaaca atttcaaagt aaaaaatata
    30181 gataatcatg ctgttcaaat tgaatatgga aatggtaaag aatatgtaga tatatttgga
    30241 cattgtgatg ttgtaaatcc aggtgaagga tgggatagtg aaccatttaa actaaatatt
    30301 ataggtgata aattagttgc tagaggtgta tctgataata aaggacctat gatagtgaat
    30361 tttttagcac taaaaatgat aaaggattta gatattaatt taaaaagaaa ggttagatta
    30421 atagctggag gaaatgaaga gagtggattt aaatgtataa agcattatta tagcaaagag
    30481 ccatatggtg tatgtggatt tactccagat gctaaatttc ctgtattaaa tggagaaaaa
    30541 ggtggagcaa taataaagtt aatttcaaat atagacgata aatctttata tataagtggt
    30601 ggaatagagt ttaatacaat accagataaa gtttatataa agaatgtaga aaaattgggt
    30661 aaagataata tatgttttga tattaacaat atatcgataa attatgataa tggcaattat
    30721 attgtgtatg gaaaaggtgg tcattcatct aaacccgaaa aatcaataaa tcctatatta
    30781 gctacaatta aacttttgtc agaaaatatt gatgaaaaat ggacaaaaga tttatataag
    30841 ttgataaatc aagataatat aaatggaaac ttatttggtt taaatattga ggggaaatgt
    30901 gggattttat caatagtgcc aacaataata aatatagtag atggaaaatt agaagtagtt
    30961 ttaagcgtta gatatccaga aatattaacc attgaagata taataaaaaa atttaatttg
    31021 tatatggagc aaaataatat taataaattt gagcttattg gggaaaattt aaagcaagca
    31081 aattatatag atagaaattc aaaacttgta agaagtttgc atgatatata tataaagtat
    31141 tctggagatt tgaaaaatga tgttagagta actagtgcag gaagttatgc ttctgaaatg
    31201 aataattcag taatatttgg ttgtgaattt cctgatggta gctttggcaa tgtccatagt
    31261 gcgaatgaat ttgctagctt agatagattt ataactgcaa taggtatata tgcagaggca
    31321 ataattacat tatgtaataa aatataaata caaaatgtcc cttatataga catattatat
    31381 atacaattaa aattttactt gatatataat tgaaatcaaa gagaaggtga tacaatgata
    31441 actaagaaac atgcaataat agtaaagagt ttaagcaata aagatggata tatgacatca
    31501 aacgaattag ctatcaaatt ggatgtgtct actaaaacta ttaaaagata tatagcagat
    31561 ttaaatagtg ttttaagcaa atatgatttg gtaatagctt cttctagagg tataggatac
    31621 aagttaagcg gttctaaaaa caatatagcc agagctgtta aagaagcaaa taaatatatt
    31681 gatggttttt tagatgactc tgaagagtca agaatgtcaa atataatatg tatgcttatt
    31741 aatagaaatt atatgagtat agaagcaatg gcagaagaat taaatctaag tatagccgct
    31801 ataaataaat tgtctagtaa gcttaaaaga aaacttgaaa agtatgactt agttataaaa
    31861 tctaaacctt actatggaag ctatatacat ggtgaagaaa ttaatataag gcaattaatt
    31921 actgactatg caataaaatt agatgaaaaa agtaaagtga aggtgttttt agatgacatt
    31981 agtgaaaacg atatatactg tatagaaagt attttagaaa agcacttaag agaaaaagat
    32041 acaataattt cagataaaga ttttaatctt ttgctttcaa aaataattgt ttctgtattt
    32101 aggagtaaga gaggtcatag taacaatata aacttaatgg atacaagtta tagatttcat
    32161 aactactact ttatagaaaa tctaatgaaa gaaatatctg ataaaattgg atttaaactt
    32221 attgaagatg aagtaattta tatttcaaat tattctggtg taatagctta taaaggtaca
    32281 caaggaagaa aaaacacaag tgaaattgag gaacgaataa gtagtgttat aagtagtgca
    32341 cttcaagata tattccttat ttcaggtagt gattatacaa aagatgatga gtttatggtt
    32401 gcaatctctg accatataaa gagattttta aatagagcta gagctaatgt aaaatcaaat
    32461 aatcctttac ttcatcaaat aaaagagaag tttcctatag cttttaattt agccgtgttt
    32521 ttatcaaata aactagaaac tgagtttaat ttaaaacttg atgaagatga gcttggatat
    32581 atagctatcc actttgctgc ttcaaatgaa agaatgaaaa aaaatactag taagaaaatt
    32641 tgtatagttt gtcattatgg gataggaaca ggacaactta tttctgaaaa gctaaaacag
    32701 aatataagtg atttaagtgt tgtaggtgtt tatccagtta gatatcttga tatggctata
    32761 agtcaagatg ttgatttgat agtatctacc gttgaattaa aaggatatga aaaacctgtc
    32821 ttatatatag aaaatatatt tgatgatagc ttaattgaaa acgtaaacaa agccttttat
    32881 gaaaaggaag aaagaagaaa gataataagt aacatgtttg atgaaaaagc ttttttcagt
    32941 ataaaggcta gtactaaaga agaggtcata atttcacttt caaataaact aaaagaaaga
    33001 gattttatag aggaaagttc tataaaaagt ataatagata gagaaaatat ttcatcaact
    33061 gaaataggaa atctagtagc aatacctcac acaatagtga agggagataa aaaatctata
    33121 ataggagttg gaatacttga aaatccaata atttgggata agcaagaggt tcagctagta
    33181 tttatggtat tttttaatac taaagaaaag cataatttct cgatatttaa atacctttat
    33241 aattttataa aagatgaagg aggagtaaga ggaattatta aaatatgtga ctttaataaa
    33301 ttaatggcac tgataggtaa ttaaggagga aattaataat gggaacaaac atatttaaca
    33361 aagaatatgt atttttaaat gttgatgcta agtcaaaggt tgaagtttta aaatttatat
    33421 caaaaaaagc taaagactta aatttggcag aagatgagag cttagtatat gaaggtttaa
    33481 tggctagaga agaacaattt actacaaatt taggagaatc tatagcaata cctcacacta
    33541 aaaatgatgc aattgaaaat ccagcagtag tagtattgaa gtttaatgaa gatgttgttt
    33601 ggaatgaagg tgaggataag gttaaattag caataagctt acttatgcca ggaaaaagta
    33661 aagagaatat tcatcttaaa ttattatcat ctctttcaag aaaattaata aataaagaat
    33721 ttaaagattc tcttttaaaa agtgataatg ttgaagaaat atctaactta ataaatgaag
    33781 ctttaggttt ataattaaat actaaggtta taaaataaaa aaataattaa ctaaaaatag
    33841 gaggaatttg aaatgaataa aaaattagta gcattatgtg cttgcccaat gggactagct
    33901 cacactttca tggcagcaga agcaatagag caagcagcaa aggcattagg ttatgaagca
    33961 aaagttgaaa ctcaaggtgc tgatggtgta caaaatgagt taacaagaga tgatatatta
    34021 ggagcaacta tgataataca tgcagtagca ataacaccag aaggtatgga aagatttgat
    34081 ggttgtgaag tttatgaagt tgaattacaa gaagctataa aaaatgcaga aggtgttata
    34141 aaagaaatag aagaagattt aggaatataa taaatttatt gtggaggaaa tagaatggca
    34201 attaagaaaa aagttataaa cagttcaggt gcttctacaa caggaggaaa taatgtagga
    34261 aaatctactc catctagtcc aactcaatca aagggaaatg gaaaatggaa agaaataagt
    34321 aaacatataa tgacaggtat atcatatatg ataccagttt tagtaatggg tggacttata
    34381 ggggccttat ctcaattaat accatatgct atattaggac ttgacccatc tgtaggtata
    34441 gttgatgcta tgaactcagg agaatttaca gggttcaagc ttagtctttt aaatatagca
    34501 caattaatgt caaatttcgg atttactttg tttggatttg cgataccact gtttgcagca
    34561 ttttgtgcaa actctatagg tggaaaaaca gctttaattg caggatttat aggtggatat
    34621 atagctaata aacctgtagg tgtaccacaa ttcattgatg gacaatggac tgaagttgtt
    34681 ccagttgcat caggattttt aggtgcaata ctaatagcat tcataatagg atattttgta
    34741 aaatggttaa ataaatctat aaaagtttct cataactggt tagcttttaa aacaacattt
    34801 ttaataccat taatagcgtc attagcttgt atggtattga tgatatttat aataactcca
    34861 tttggtggat taattaatga aagtatgaaa aacttcttaa cagcagcagg agcagctgga
    34921 gaatatgtat atgcaacagc tttggcagca gctacagcat tcgacttagg aggaccaata
    34981 aataaagcag caggattcgt tgcacttggt ttaactacag agaatgtact tccaataaca
    35041 gcaagaacaa tagctatagt tgttcctcca attggattag gattaacaac attattagat
    35101 aaaagattag taggaagaag agtatatgat agacaattct atcaagcagg aaaaacttct
    35161 atattcttat catttatggg tatatctgaa ggagcaatac catttgcact tgagagacca
    35221 ggttttgtta tacctttaaa catagttgga agtgtaatag gagctattac aggtataatt
    35281 ctaggagcaa ttcaatggtt cccagagtca gctatatggg catggcctct agtagataac
    35341 ttatttggat atataatagg tatagcagtt ggtgctatat tcatagcagt aggaaatata
    35401 ttctatagaa ataaattaat aaaagatggt aaacttgttg tagattatat cgactagtat
    35461 ttaattttta ctatctataa ataactttgg ctggtaatat ggttttaatc aatattacca
    35521 gccttaccta tatgattaat taaaggcggt ggagataaga tatggataag atagaaaaag
    35581 taagagagta ttttagagaa tatgatatag atggatttct tataaatagt cctacaaaca
    35641 agttttatgt tggaaattta tttagctctt caggttatgt ttttataacg aaagaatcac
    35701 aatatataat agtagatttt agatattttg aagaaattaa aagaaaatct agtttgttta
    35761 atgtagtatt aatggacaaa actagaactc attttgatat aattaatgat atttgtagag
    35821 agcagaatat aaaggaaatt ggatttgagg gaaatgaagt atcttttgat ttatatagaa
    35881 gtatgagtaa taagttaagt gcaaccttaa aatcagttga tttatctaca ttaagggaaa
    35941 caaaaaatga agacgaaata aaatatataa aaaaagcttg tgaaatagtt gatgctacat
    36001 tttatcatat agtagacttt ataaagattg gtatgactga aaagcaagtt gaaaatgaaa
    36061 ttgttagaat tataaaagat ttaggtggtc aaaaagaatc tttcgataca atagttgcat
    36121 ctgggcttag aggagcatta cctcatggaa aagcaagtga aaaaattata gagtatggag
    36181 attttgttac ttttgacttt ggtgctaagt ataataatta ttgttcagat attaccagaa
    36241 ccatttgtat gggtactata aataaagagt tagaagaaat atataatata gtaagaaaag
    36301 ctaatgaaga gtgtataaga gttttaagac cgggaatgac tactggagag atagataaag
    36361 ttgcaagaga cataattggt tcatatggat atgccaataa ttttggtcat aatctgggtc
    36421 atggtgtagg aattatggtt catgaatatc ctgccttagc tcctgaatca aatgaagtat
    36481 taaaagaagg aatgattgta actatagagc ctggtatata tgttccaagt cttggaggcg
    36541 taagaataga agatgatgta ctcataacac aagatggatg tatgagattg actacatcta
    36601 ctaaggattt aatagttgta agctaaaaat aaattagata aatattttat aacaataaga
    36661 aaagaagagg taaatttaaa tgtataattt tgatgataaa ccagatagag taagtgaaaa
    36721 gtgtagaaaa tgggatttaa atattataag agataaattt ggagatatta gagaagattt
    36781 tgtaccaatg tggattgctg atatggattt taaaatacca acagaaatag aaaacaaatt
    36841 tattgaagct gtaagaagag gtgtatttgg atatacatac tgttatgatg aattttatga
    36901 ttcagttatt ggttggcaaa aaaatatgca tgaggtaaat gtagaaaaag aatggattac
    36961 attaacttat ggaactgtat caacacttca ttatgtagta caagcttttt gtaagaaagg
    37021 tgatagtata atattaaaca caccagttta tgaccccttt gaatcatcag caaaaaaaca
    37081 aggtgtaaat gtaatttgta atacattaga tgttgtaaat gatagatatt atataaattt
    37141 tgataaatta gaagttcaaa ttaaagaaaa taagcctaaa ttaatgatgt tttgtacacc
    37201 acataatcca tctggaagga tatggacaat tgaagaaatg acaagggtag caactatatg
    37261 taaagaaaat aatgttattt tggttgcaga tgaagtacat gcagagcata ttcattatgg
    37321 taaatttaat tcaatactta agattggaaa agagctttta gaaaatgtta ttctactgac
    37381 atcaccaaat aagggcttta atcttggtgg attaaagact tcttattcaa tagttataaa
    37441 taagaatata agggataaat ttagaaataa attaaagcaa aattctataa cttctccaaa
    37501 tgtgtttgga ataataggat tgataaccgc ttataatgaa tgtcatgagt ggttaagtgg
    37561 tgtaaatgaa tatataaaat caaattatga acttttagaa acttgggtaa ataaatataa
    37621 taagataaaa ttgatgaaaa tggaatcatc ttacttagct tggatggata taagtggatt
    37681 aggtataagt gcaagtgagt ttacagataa attggctata gatacaggag tattattaga
    37741 agatgggagt cattttgtaa aagatggtga gaagtatgtt agaataaatt taggaactca
    37801 aaaggaaaat gtaattgaag ctttaaatag aatggattta tttttaaagt ctttataaaa
    37861 atttggttga attagtattt tatataaatt taagctatta atatggtata tacataagta
    37921 gaatttgttt tagattactt aagtatatac catattttat ataaaaatta aatttgcatt
    37981 agtcatgtga taactattta aattcatatg tattttgtat gtataataga tataattatt
    38041 atttaaactt attgtttatt taatttttca atagaaaaag atttatctgt aagtttaaaa
    38101 ttatctttta tacccttagt taaatatact ttcttatcct tagttatgaa tatagcatct
    38161 acattatcaa tttcattaat taaatccata cctttttcaa gaccaagtcc aaatgtagaa
    38221 gtggataagg catcacaatt aatagattta tcagaaatta ttgtaacact acttagattg
    38281 ttttcaaaag gataccctgt aaatggattt aacatatgat gatatatttt tccgtctttt
    38341 tcgataaatc tttcataaat tccagaagta acaacagatt tatttgtggt ttctatgttt
    38401 cctatggatt caccattttt actagtgggg tcttgaatgc ctattttaaa aggtttatca
    38461 tttttaccat cttctaaagt aaatatattt cctcctaagt ttactaaacc tttttttacg
    38521 tcctctgatt ttaaataggc tacaatttta tcagcagcat atcctttagc tatggcacct
    38581 aaatcaattt tcatattttc tttggttaat tttatagatt tatttttttc atccaatatg
    38641 atgttcttat aatcaataag aggcagaagt ttttgtatct cagaatcact tggaacttta
    38701 gctttatctg ttccaatagc ccataaattt gataatggac caattgttat gtcaaaatat
    38761 ccatctgata atttggaata ttgtatagct tcttttacga cgaaaaatgt atcatcagaa
    38821 actctgacaa attttttacc agcattatca tttattttag aaacatcact tcctggtata
    38881 tgagtgctca ttttgttgtc aatatatctt aaaattgaat cacattcatt taagatttta
    38941 tcacttttgg attcttttac attaaatata gtaacttcgt ttactgtacc aaggtagtag
    39001 ctagttttac tatatttagt attctggctt gaactcctaa aaaatgaaaa taaaattaat
    39061 gctaaaatca atatcacaaa aataaatgtg atttttttct tattcatggt atattcctcc
    39121 tatgaaattg tgttattatt ttattataac ataatttcat aggaggacaa aaaatgaaga
    39181 aaaaagacat tcttcttatt ttaggcattt tggttgttat tatagcatgt tatgggataa
    39241 taaatgttat aaattctaaa aatgctggaa atattgagat ttatgtagat aataaattgt
    39301 ataaaactgt ttcaataaat gccaaagaag aatttaaaat agagaataga ggggggtata
    39361 acatagtaaa gattcatgat aaaggggttg agatagtaga tgcttcatgc cctgataagg
    39421 tttgcgtaca tactggattt ataaacaagc caagtcaaag catagtttgt atacctaata
    39481 gagtgagcat aaaaataaat acaaatgaaa agaatgataa tcaagaagat ataatttcta
    39541 aataaaataa taaaaataat tgaaaggaat tggtgataat tatggttaac ttaggaaacg
    39601 attgggatga attattgaaa gaagaatttg aaaaagatta ctacttaaac ttaagaaaat
    39661 ttcttataga agaatataaa acacgccaaa ttttcccaaa tatgcacaat atatatgaag
    39721 ctttaaaaca cacttcatac aaagacacaa aagtcttaat attaggacaa gacccttatc
    39781 atggagataa tcaagctcat ggtttagctt tttcagttca accacaagtg aaaactccac
    39841 catctctatt aaatatgtat aaagaattaa aagatgattt aggttgtttt atacctaata
    39901 atggatattt aatgccttgg gcagaccaag gagtgttact tttaaatact gctcttactg
    39961 ttagagcgca tgaagctaat tctcataaga acaaaggatg ggaaattttc actgatagag
    40021 taatatctat tttaagtgag cgtgaagacc cagttatttt tgtactatgg ggaagtaatg
    40081 cacgtaaaaa agtagagttg attgatacaa gtaaacatta tattttggaa gcacctcatc
    40141 caagcccatt gtcagcaagt aaaggctttt ttggatgtaa acacttctct aagataaatg
    40201 aaattttgaa aaagctagga aaagaaccta ttaattggca gatagaaaat atataaaagt
    40261 aaaaggtaac aaaatgataa caaaacaaca ataaacaatg acattgttgt aactaataga
    40321 aatatgctta aatagttgaa aatactatgt atgcatattt ctattttttt gtcaagttga
    40381 caactcttga aaaaatagtt acaatttagt tacacaaaaa acacaaataa aaaaagaaac
    40441 ttacaaagca gaattttatg aagcaaaata tatagtgtaa aaaattttag ggaggaaatt
    40501 ttatatgaat tttaaaaaat tgagtaatgc taaagtctcg gtaatggcag ttgttttatc
    40561 agttggaata ttatcgggat actctgcgct taataaacaa gtaacattag tagtaagggg
    40621 agaagaaaga actatatcaa catttagttc taatgtagga gaccttttag aatctcaaaa
    40681 cattagctat gatgcaaatg atatagtaac tttagatgaa aatacaaagt tatctaatgg
    40741 agataaaata gaagtaattg atgtaaagga aaaaacagtt gtagaaacta aagacattcc
    40801 atttgaagtt acagttgttg aagatggctc tttattaaag ggtgattcta aggttaaaga
    40861 agaaggaaag tctggtaaaa gtgaattaat atataaagaa acttatcaca atggaaagaa
    40921 agttgaaaag gaatttgtga aaaaggttgt taaagctgag ccagtaaata aggttgtaag
    40981 caaagggaca aaggtagaaa tgcaagtagc ctcatcaagg ggagaaagtt caagaagaat
    41041 ggcttcatca tcatctagta gcagtagtag taacaatggt aaaaatatga gagtggtagc
    41101 aactgcatat actggtcata gtataactgc aacaggaaca aaacctaagt ggggaacaat
    41161 agctgtagac cctaaggtta taccatatgg aactaaagtt tatatacctc aatttgacat
    41221 ggtgtttact gcagaagact gtggtggagc aataaaagga aataaaattg atatctacat
    41281 gaatgattca aaaacggttt ataactgggg aagaaaaact atagatatac gtatattaaa
    41341 atagttaaat aatttatatt tttactggaa attatatttt gattatatag agaagaaact
    41401 ctttatagat tcttaaaata taatttccag tttttatttt ggatatgtaa taaaacaggt
    41461 aaattttaac catgtataga taaaagctat ttaaattata atttactatc agataaatct
    41521 ataaaaattg ttgcaaagag tcaaaatata tgatattata gatttcgttg agaaggattt
    41581 cattatggga gtggatgggt gccggtgtgc cctctagtct tcaaaactag tatgaggggt
    41641 taagagcctc ttaggtgggt tcgattccca cgcattcccg ccaatatgca aaaggtatct
    41701 tttaattaaa agataccttt ttaaatttat tttaagataa tttattttta ataatatata
    41761 atgttttgta ttatataatg taaattttct aatactatta tatatttaga taaaaatcta
    41821 ggagtgtgga aagatggaaa ataattttac aacgagaact agttttctag ttggagatga
    41881 tgggatagaa aaacttaata attcaaatat aatagtattt ggagttggag gagttggtag
    41941 ttttactgtt gaagctttag caagagctgg agtaggcaat attactattg tagattttga
    42001 tgatgtagat ataaccaata taaatagaca aataccagcc ctacattcaa ctgtaggaag
    42061 gtacaaagtt gatgtcatgg aagaaagaat attagatata aatcctaata tcaatataaa
    42121 aaaaataaga agtctttata ataaagatac tagtgacgaa atactaactg aaagatatga
    42181 ttatgttgtg gatgcgatag acatggtaag ttccaaaata catctaattg aaacttgtga
    42241 aaaaaaaggg ttgaaaataa taagttctat gggtatggga aataaattag acccaactaa
    42301 aatagtcgtt acagatatac acaaaacaag tacttgtcct ctagctaaag ttatgaggaa
    42361 agaacttagg gatagaggta tcaaaaagtt aaaagtagta tattctactg aacaaccaat
    42421 agaacttaag aagaaagtaa tgaatggtag aaaagtaaca cctggtagtg tatcatttgt
    42481 cccatctgta ggaggtttaa taatcgcatc tgtaatagta aatgaactat taggacaata
    42541 agttttaaat attttaattt ataaatttta tatacaaatt tgaaggctag aagcatgaat
    42601 ataaagcaat tttatattca tacttttagc ctaattattt tatattacct tattttatgt
    42661 agttgtagtt ttatttttta gattatgtat ctatttcata attatatttt gtaaatataa
    42721 tttctccatc actataaaaa acaatatctc ctattctatc tgttctataa attgatacat
    42781 ggttttgttt tagattatta ataacctccc tatgtggatg accatattga tttttatatc
    42841 cacatgatat tgcagctata tctggactaa ttttttttat aaattctaaa gatgaagaag
    42901 aattacttcc atgatgacct atttttataa aattaatatt atttaattta aaagaatgta
    42961 aaatttcttt ttcattttct tcttcagcat cacccataaa taaaaaagaa ttatcgttaa
    43021 aagttaattt gaaaactata gaatttaaat tagattcttc ttgtatatat gatggactta
    43081 atacatatat atttatattg ttatctatgt ttaaaacatc atttttatag agatgctgaa
    43141 tagataagtt tttatccgta caagaattta ttagattttg ataagcctca ctatcagttg
    43201 attgttcagg catatatatg gagtttacat taaatttttt tataacatta tcaagacttc
    43261 ctatgtggtc tgaatctgga tgagttgcta ttataatatc aatagttttt attctttttt
    43321 gtctaagata actaataatt atattttcgc tatcttcatc acctccatca attaatatat
    43381 tcttatttgt gggtgtttga actaaaatac tatcaccttg tccaacatca attatatgta
    43441 tagatagtag agattttttg tcacagccga ttaaaagtga tattataata agtattgata
    43501 aaaaaatttt atttctcaat aaaaaatcac tccattcatt acatgtttat ataaatttat
    43561 gatgggtaat ataagatata tatgacttat tatattttat attttaaaca atataaatga
    43621 aattaatacc ataataaatt tggagttttt tatatataca aaataaaatt tttaaaatta
    43681 agcaataaaa aaggtaggag gattttatgt ttttcaaaga tattgaacta aattcaaaaa
    43741 aagagttaga cccatatttt gatttagtag attatgaagc ttgtgagtac tgttttagta
    43801 ctttatatat gtggcaacat gtttataaga caggatatta tataggtgaa gattttgccg
    43861 ttttagttgg ggaatacgaa ggagatagtt tctcaatatt accacttgct aaaaaagata
    43921 aacttccaga agttgtagat tttgtccttg aatatttttc taaaaataat aaaaaaatat
    43981 acttaagagg tattactact gaagtagtag agtttttaaa agaaaaatat ccaggtagat
    44041 ttgagtatat agaagaaaga gatttatttg actatattta tgatgcagaa agtttaagaa
    44101 ctctagctgg taaaaagaat caaaagaaga gaaaccatat aaactatttc ttaaaagagt
    44161 atgcaggtag atatgaagct aaattattag ataaagaaaa ctttgacgag tgtttagtac
    44221 taatgaagga atgggaaagt aataaggaag aaaataatga atttgatgaa agtatggatg
    44281 acgaattaat aggtatcaaa aagatattta accattatga catattaaaa gataaggtaa
    44341 aagtgtttgg tgtttatgtg gatggaaaat tagaggcttt tagtatagga gaacttttaa
    44401 atccaaatat ggcattgatt catatagaaa aagctaatcc cgatataaga ggtctgtatc
    44461 catttataaa tcaacaattt ttggtaagtg aatttaagga cgttgagttt gtaaatagag
    44521 aagaagattt aggtattgaa ggattaagaa aagctaaact ttcttatcat ccttgcagat
    44581 ttgttgaaaa gtacagtgtt agggaggctt aatagactat atggagatta ggtatgctaa
    44641 agaagaagag atagaaagta taaaagagat ttggagttat tgttttaacg atacggagag
    44701 ttttatgaag tactatttta atgataaata taaatctgaa aatactgtag tagctttaga
    44761 tgaaggaaaa attatttctt ctcttcagct aaatcagtat aagttattac taaatagcaa
    44821 ggtatataat acatcatatg tagtaggagt ttctacactt ccagagggaa gaggagctgg
    44881 atatatgaac aaagtaatga aatttacttt aaacgaattg tataaaaaag ggcaattagt
    44941 ttctatattg atgcctattg actatagact ttatagaaga tttggatatg agcattgtta
    45001 cgaccagatt gaatatacta ttaacacaga tgatttaaaa aattttaagt caagtggaaa
    45061 aatgataaag tctaatttat cacaaattga tgatttgata cgaatagata gaactttttt
    45121 aaatgaggtt aatggtaatg tgttaaaaga tgaacattat tatgaaaact tatttaaaga
    45181 gattcaaagt gaagatggat ttttatacat tcatgaagga aatgaaaaag atggatatat
    45241 agtttatttt cttcaggaag ataaaatgtt tgtcagagag ttattttata aaaatataga
    45301 tgcccttaaa tcaatgctta aatttatata taatcacaat actcaatgta agatagttac
    45361 tatatctact cctacaatag ataagataag atttatatta gacaacccta aagatagtga
    45421 tataaaaata aaacctttta tgatgggaag agttataaat gtaaagaagt ttattgaaga
    45481 tatagatatt gagaaggata ttaatagctc atttaattta ttaatagaag acaagtttat
    45541 agatgaaaat aatggtctat ttaaaatttc tatacagaat aagaaggtat ctgtagagca
    45601 gttagataaa aaaggtgcag aaaagcctca agaagatttt gatattaaat tagatataaa
    45661 taccttaaca cagttatcat tttcttatat agatgtaaat gaagctattt tcttaaatga
    45721 tataaaagat gtttcagaag aaacactaga aacacttaat tgtatttttt ctaaaaaaaa
    45781 tacctatata aatgaatata tataggtaga atacgttaaa agattttaaa aatcttttga
    45841 cgtatttttt tgtttagata acaatttatc ttgtttaaaa attttctatt tgaaaataat
    45901 ctaaataata tacttttata tgggagtgat tataattcaa ataagaagac cattattaat
    45961 tatattaatg tttgtggtag ctatatcatt tatcattaca aataacacaa aaaacgacga
    46021 agaacttaat gataagataa taactataca aggggttgtc aaaggaaaaa ttgaaaagaa
    46081 aagatacaat cagtacaagg taggggtttt tctaataaat gattatacaa aaaataaaaa
    46141 tttgaagatt ggtcagaaag ttaatattac aggtaaattc aaaagtttag ataaaatgaa
    46201 gtatgatgat tttgattatg gaaggtatat aaaaagtact ggatataaag gtatagtgta
    46261 tataaataac tataaaatta ttgataaaaa taaactttac tctttaatag gggaaataaa
    46321 gttttatatt agtaaaactt ataggtactt atataagaaa aactcagatt ttataaattc
    46381 tatactatta gcagaagttg aaaatttgac tgaggaacaa aaagaaattt ttactagaac
    46441 tggaactagt catgtaatat ctatatcagg tcttcataca ggaatattat gtgtaattat
    46501 atcctttcta ttaagaggta taaataaatt gtataaatta ttaatactgt cgatttttat
    46561 aactttatat tgtataatgg taggtgcgtc tccatccata attaggtcta tagcatttgt
    46621 tatgattttt tatttatcaa tatttattga tagaaagaaa gatggaatat cagcattgtc
    46681 tctaattggg ataattttaa ttatgaataa cccctatgtt atatataatg taagttttca
    46741 attgtctttt ttagctacac tttctatatt aatattctat aataaaataa atagtattat
    46801 aaaattaagt atggtatcat tgacaatatc atcaaatata ttaactttac ctataattta
    46861 ttatacattt aaaggtatac cattgctttc aattatagga aatttaatta tagtaccatt
    46921 tgtgggagta ataatgtatt taagtattgc aagtttaatc gtatttaaag taagtgtagt
    46981 aatagctaaa attatatctt tttttaatag tacattgata gaaagcatat tttttttact
    47041 agaaaaaatc agcaatttaa gttttgcata cattaatata gaaagtccta aattttatat
    47101 tgttgttatt tattacatag gagtgttttt ttacatattt tacatagaag gaaaagagat
    47161 aaaggagcaa gagaatgaat tacaaggata ttataaggaa tgtaaaagag aaaaactttg
    47221 aaaaaatgta tcttttttat ggaagagagt attatttaat tgagaatgca ataaaagcat
    47281 ttaaagatag tctaaacgaa ggaatgcttg attttaattt agatataata gatgggaagg
    47341 aaatagtctt aaatcagctt ataagctcta tagaaacact tccatttatg gatgatagaa
    47401 agatagtaat aataaaagac ttcgaactat taaaaggaaa gaaaaagaat tttacagata
    47461 gtgatgagaa atacttaata gagcatttag ataatattcc agacactaca actatagttt
    47521 ttgttgtata tggagatgta gacaaaagaa aatcattagt taagaaaata ggaaacaatg
    47581 gaattgtttt tgattgtgat aagctttctg atatggattt atttaaatgg ataaaaaaat
    47641 cttttgcttt aaatgatgtt ataatagata attctcaaat catgtatttt attgaacaag
    47701 aaggatacag agataagagc agtgaaaaga cattatctga tttagaaaat gaaataaata
    47761 aaataagttc ctttgttggt aaagggaata atgtaaccaa tgacgtaatt gataaattat
    47821 ctcaaaaaaa agttgagaat gatatattta aattaatcga ttatattgga gaacaaaatg
    47881 cttctaatgc aatgaaaata ttaaatgata tgatacaaga aggcgaatct gtattaggta
    47941 tattttctat gatagcaaga caatttaaaa taattatgca agtaagacag ttacaacttg
    48001 atggatattc aacaaaactt atagctgata aattaaaaat gcatcaattt gttgtaggaa
    48061 aagcattaaa gcaaactaaa aatttttctg atgatataat tgtggaaata ttaaactata
    48121 tattagaaag tgattataaa ataaaaacag gtcttataag agatacttta gcagttgaaa
    48181 tgttggttag tagatactgt aaaagagaag caatttaaaa aatctatata ttaataaaaa
    48241 ataaatagca agatatgtta tagttcagag tagatgtaag ctaaattaag tttgatatac
    48301 aatcaactat aatatgtcta actatttatt ttttattgta taaatttaca aaataaaaaa
    48361 cccctacata ggggttatta tatataagaa atataaactg gtaattaagc gttcataccg
    48421 tttaattttt gagctaattt agctactttt ctagctgcag cattcttatg tatagttcct
    48481 ttagaagcta cttggtatat tcttttttga gcgtattgga actttgcaac agcatcctct
    48541 ctgtttccag ctgcaacagc atcttcgaat cttcttattg cagtttttat ttgagatttt
    48601 ctaactctat ttaaagcagt tttcttttcg ataacactta ttcttttctt agctgatttt
    48661 atatttgcca ccgtgttcac ctccctgtat ttttttatca tattcatcgt caacatatta
    48721 gattttaaca gaaataaatc taaaaatcaa ggattattat ttatatattt taataatgtt
    48781 ttttattttg attttttaga ctgtaaattg tgtataaata atttgcaata tcttgttttt
    48841 aaattggtat attttgtgtt ttaaatattt tgacatatat aaattaatat tttatttttg
    48901 taacaaatat tttgagataa tacaaactat taacatacat tttgatagta tttccaataa
    48961 ttataagaaa atac
//
LOCUS       DAEQJM010000026        46450 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.026, whole genome shotgun sequence.
ACCESSION   DAEQJM010000026 DAEQJM010000000
VERSION     DAEQJM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46450
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.026"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            151..717
                     /locus_tag="KRQ43_001805"
     CDS             151..717
                     /locus_tag="KRQ43_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HBH2742162.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            1022..1483
                     /locus_tag="KRQ43_001806"
     CDS             1022..1483
                     /locus_tag="KRQ43_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2742163.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1551..3797
                     /locus_tag="KRQ43_001807"
     CDS             1551..3797
                     /locus_tag="KRQ43_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742164.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3790..5622
                     /locus_tag="KRQ43_001808"
     CDS             3790..5622
                     /locus_tag="KRQ43_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742165.1"
                     /translation="MSRMGRGPMGKSMEAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6341..7618
                     /gene="hflX"
                     /locus_tag="KRQ43_001809"
     CDS             6341..7618
                     /gene="hflX"
                     /locus_tag="KRQ43_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH2742166.1"
                     /translation="MDMTKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELYDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDCVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7851..8348
                     /locus_tag="KRQ43_001810"
     CDS             7851..8348
                     /locus_tag="KRQ43_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2742167.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8398..8922
                     /locus_tag="KRQ43_001811"
     CDS             8398..8922
                     /locus_tag="KRQ43_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH2742168.1"
                     /translation="MKSVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKDLQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKVPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILNYIRKL"
     gene            9234..10598
                     /locus_tag="KRQ43_001812"
     CDS             9234..10598
                     /locus_tag="KRQ43_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBH2742169.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSNFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVENTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            10737..11903
                     /locus_tag="KRQ43_001813"
     CDS             10737..11903
                     /locus_tag="KRQ43_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH2742170.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            12020..12802
                     /locus_tag="KRQ43_001814"
     CDS             12020..12802
                     /locus_tag="KRQ43_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBH2742171.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYAESLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(12921..13574)
                     /locus_tag="KRQ43_001815"
     CDS             complement(12921..13574)
                     /locus_tag="KRQ43_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2742172.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(13598..14962)
                     /locus_tag="KRQ43_001816"
     CDS             complement(13598..14962)
                     /locus_tag="KRQ43_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH2742173.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            15620..17050
                     /locus_tag="KRQ43_001817"
     CDS             15620..17050
                     /locus_tag="KRQ43_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2742174.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            17153..18256
                     /locus_tag="KRQ43_001818"
     CDS             17153..18256
                     /locus_tag="KRQ43_001818"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH2742175.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMTYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            18271..18507
                     /locus_tag="KRQ43_001819"
     CDS             18271..18507
                     /locus_tag="KRQ43_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2742176.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEKACQEA"
     gene            18524..19573
                     /gene="vorB"
                     /locus_tag="KRQ43_001820"
     CDS             18524..19573
                     /gene="vorB"
                     /locus_tag="KRQ43_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH2742177.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            19575..20315
                     /locus_tag="KRQ43_001821"
     CDS             19575..20315
                     /locus_tag="KRQ43_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH2742178.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            20318..20857
                     /locus_tag="KRQ43_001822"
     CDS             20318..20857
                     /locus_tag="KRQ43_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH2742179.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLLEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            20981..23080
                     /locus_tag="KRQ43_001823"
     CDS             20981..23080
                     /locus_tag="KRQ43_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HBH2742180.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKMIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWALDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNTKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(23347..23862)
                     /locus_tag="KRQ43_001824"
     CDS             complement(23347..23862)
                     /locus_tag="KRQ43_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HBH2742181.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(23954..25165)
                     /locus_tag="KRQ43_001825"
     CDS             complement(23954..25165)
                     /locus_tag="KRQ43_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH2742182.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDFPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            25841..27283
                     /locus_tag="KRQ43_001826"
     CDS             25841..27283
                     /locus_tag="KRQ43_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH2742183.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            27325..27678
                     /locus_tag="KRQ43_001827"
     CDS             27325..27678
                     /locus_tag="KRQ43_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742184.1"
                     /translation="MKKSNIFSIIFPTIIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            27869..28690
                     /locus_tag="KRQ43_001828"
     CDS             27869..28690
                     /locus_tag="KRQ43_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH2742185.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIKKVKSNNIA"
     gene            28948..30831
                     /locus_tag="KRQ43_001829"
     CDS             28948..30831
                     /locus_tag="KRQ43_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBH2742186.1"
                     /translation="MFNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            31055..31735
                     /gene="pgmB"
                     /locus_tag="KRQ43_001830"
     CDS             31055..31735
                     /gene="pgmB"
                     /locus_tag="KRQ43_001830"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH2742187.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            31732..34017
                     /locus_tag="KRQ43_001831"
     CDS             31732..34017
                     /locus_tag="KRQ43_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH2742188.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNKVASIEKYVSITSTRDYKESELLR
                     KCEDILNIELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNCIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGK
                     PIKIIVYGKKYILEKYIKIDK"
     gene            34243..35136
                     /locus_tag="KRQ43_001832"
     CDS             34243..35136
                     /locus_tag="KRQ43_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH2742189.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIAEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEV"
     gene            35184..37484
                     /locus_tag="KRQ43_001833"
     CDS             35184..37484
                     /locus_tag="KRQ43_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742190.1"
                     /translation="MKKIFSIFISCMVVVTTITGCSSGEVIKNTSPINSVKNLDFSFE
                     VKPEIFEVSVESGGSKEKISEPSKERKVSNFKKNKTEASWTYPDENIDINIKKEDSYL
                     DVNIKSNLEKETSFNWPKVEGESYILPLYEGKFIPSNDKYWKEYLNESTYNVIESFSM
                     QFFAVNKAKYSVIYIIENEFNNVIEFSSKDKINFTFKHEYPSINKNKEYGFKIYLTNK
                     NITDVAKTYKNYIVDKGEFKTLKEKSKENKNIEKLYGAPHIYFGDKSIITINDIEWNK
                     LKENLSDDLTNWMKELLSMKSGNSEFIKVINQIKTQDYIDKYQKNQIVQAFNEVMQMN
                     TFYNEKVFESKDREIKKVLDKGISKLSRVELIEFNKKLLKSKLEESVNDVATWAKYNT
                     TDVINDINKSGIKNAWIGFDDMEEGYISLEMVKRANELGYLVGPYDSYHSIHKPGEEK
                     WSTASFKDKSLYENATIENKKGEKETGFQGEGRKLNPTLSLPSVKERVQSILDEGYEF
                     NSWFIDCDATGEIYDDYSQNHITTQTQDLNARLERMSYIRDHANMVIGSEGGNDFSSS
                     TIAFAHGIETPAFAWVDKDMSKNKGSEYYVGKYYSPTGGVPEIFSKQIPVKERYKKIF
                     IDPIYSLPLFRLVYNDSVISSHQWLWGTLKIKDEVGSRMMKEVLYNTPPMYYIDRTEW
                     EKHKDEIISNNKVWSAFNKKAIKKEMTDFKFISEDRLVQMTEYGEDLKVLVNFSQKDI
                     KYNDEVIKANSLVIYDADSKVIYKPE"
     gene            37718..38209
                     /locus_tag="KRQ43_001834"
     CDS             37718..38209
                     /locus_tag="KRQ43_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBH2742191.1"
                     /translation="MYENNKVIYNFERCEKLENALYLSQFNTYKNFKLTSKKTVINSL
                     DTSTYNMNIHSISLVDTMECISSEDEQMTGKKLILVGDIDTDVTLDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            38237..39184
                     /locus_tag="KRQ43_001835"
     CDS             38237..39184
                     /locus_tag="KRQ43_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742192.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNSIVFGCIEVEIDYSCKNR
                     SNFKTVNKFNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
     gene            39474..40016
                     /locus_tag="KRQ43_001836"
     CDS             39474..40016
                     /locus_tag="KRQ43_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH2742193.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            40341..41834
                     /locus_tag="KRQ43_001837"
     CDS             40341..41834
                     /locus_tag="KRQ43_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH2742194.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTVSFAIPLCENINVDCNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINKGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKVNELKDIEKSRITHGKILFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            42071..42835
                     /locus_tag="KRQ43_001838"
     CDS             42071..42835
                     /locus_tag="KRQ43_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2742195.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(43120..46299)
                     /locus_tag="KRQ43_001839"
     CDS             complement(43120..46299)
                     /locus_tag="KRQ43_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH2742196.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKRDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNIHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKETTIENKLTSSQFTKENNHYVFKGTDYDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIYKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIIDLFN"
BASE COUNT        18254 a         4982 c         7811 g        15403 t
ORIGIN      
        1 acttataaat acaagttata tacaagattt atagtagagt aataatctta taaaataatt
       61 taataaatat aaattaaatt atatgtgtat atattgtact ttaatagtga tataataata
      121 aaaaaatttt taaagagggt gatattacat atgagaaaac ttgaagagat attagaatat
      181 aataaatcat ttgtagagaa caaagaatat gaacaatatg tgacatcaaa acatccaaat
      241 aaaaaaatag tagtcttatc ttgtatggat acaagattaa ctgagctttt gcctaaggct
      301 atgaatttga aaaatggaga tgtgaaacta ataaaaaatg caggagctac tataatgcat
      361 ccttttggaa gtattatgag aagtgtttta gttgcaattt acgaatttga tgtagatgag
      421 gttatggttg tagggcatca tggatgtggt atgtgtaatg ttgatacaga taagttactt
      481 ggtaaaattt tagatagagg aatatctaat gatgtaatac ttacacttcg tagtgctgga
      541 attgatacaa aacaatggtt acatggattc gattctgcag aagaatctgt aaaagatagt
      601 attgatttaa taaaagggca tcctttaatt ccagatggta ttattgtaca tggtctaatt
      661 atatcacctg aaactgggaa gttagacgtt gttgtaaatg gatatgaaga taagtagagt
      721 attgtaatgt tatataatca agatactgtt gaatatgatg ttgtttcaaa atttattttg
      781 ggacaacttt tttatttgaa aatatatgaa aaggtttatt ttaagcttta caataaaaaa
      841 tataagtagc tgactaatta aaaatcttac tattatttat taaaattata actatatgat
      901 ataaaaatat ttaataaatg aaatttatat gaatttttta taaatatatt gaaaaaatgc
      961 atgcagtata gtaaaataat gcttagccga ctaagtaata taaaaaataa ggagggcaag
     1021 tatgaatagc aattctgaag aaaaattaaa tgatgttttc ttgcaattaa tgcgaatata
     1081 ttttataaga actcattttt attttgataa attaggctta tatcatggtc aaccccaaat
     1141 acttttttct ttaaagatga aagatgggca aagtcaaaaa gaattagcag ataaaaggaa
     1201 agtaaaagca tctacaacta cagttatgat aaagaggatg gaaaaagctg gacttgtgga
     1261 aagaaaacaa gatgaaaagg accaaagagt atctaggatt tttttgacag acaaaggttt
     1321 agaaatatgt aataaagttg aagaatttaa caaggaattg gaaagagagt tttttttagg
     1381 atttagtgaa gaagaaaaaa tagtacttag aagacttcta atgcaagtac gagataattt
     1441 aaaagcagga tgtcataagc atgaagatga aaaatatttt taaagtttaa aataatgttt
     1501 ttcaatttaa tgttattaga ctaattaata ttacagaagg gaagaaatgt atgtttaaat
     1561 taattaaata tttaaagaaa tcggcattat caatagtaat aatagtctgt ctattggtaa
     1621 ttcaagcggt atgtgacctt tctttaccag aatacacatc caatatagta aatgtaggta
     1681 tacaacaagg tggagtagaa aactctgttc catctgtgat tagagagagt gaattaaata
     1741 aaattacttt atttatggat aaaagtagta aggataaagt actagataat tatactttgc
     1801 tgaataaaaa ggattatgtt aagtataaag ataagtaccc aggtctaaaa gatgaatctc
     1861 tttatgagtt aaatactaaa gacaaagaca ctatagatga tttaaatgtt atttttggta
     1921 aagctatttt aatagtatca gggcttgagg gcgatagtaa agaggtaaaa gctatgaaag
     1981 ctcagttaat gagtaaactt ccaccacaag ctactcaaag tggagatgtt gatatattta
     2041 aattgttatc agcaatgcca aaggaacagt tagatacatt gactaaagag atgagcaaag
     2101 gctttgaaag tatgccagag agtatgataa cacaaagctc tgtttcatat gtaaggtcag
     2161 aatatgagaa aataggtatt gatacagaaa aaactcaaaa taattatata ttatttactg
     2221 gtgctaaaat gcttggtata gcaatgatta gtatggtagc tacaataaca gtaggatttt
     2281 tagcagcaag agtagcagca agtgtaggta gaaatttaag aagtggagta tttagaaaag
     2341 ttatgtcatt ttcaaatact gaaatgaatg aattttctac agcttcatta attactcgta
     2401 gtacaaatga tattcaacag atacaaatgt tgatggttat gttgcttaga atagtattct
     2461 atgcacctat aatggctata ggtggagtga taaaggtttt aaacacaaat acttcaatgg
     2521 cctggattat agcagtagca gtagttgcta tcttatcatt aattgtagtg ttattctcag
     2581 tggttatgcc taagtttaaa ctggttcaaa agcttgttga taagttaaac ttagtaagcc
     2641 gtgaaataat tactggtatt ccagttatca gagcttttag tactgaaaaa catgaagaag
     2701 aaagatttga taaagcaaat aaaaatttaa ctaaaacaaa tctttttgta aatagagtta
     2761 tgacatgtat gatgcctgct atgatgctta taatgaacct tatcacagtt cttatagttt
     2821 ggagaggtgc atacagtgtt gattctggag caatgcaagt tggagatatg atggcattta
     2881 tacaatatac aatgcaaata ataatgtcat tcttaatgat atcaatggta tctattatgc
     2941 ttccaagagc atccgtttca gctacacgta tagatgaagt attagtgtca gatataagca
     3001 taaaagaccc agaaaaatca gaggcacaag agtttaagga agataaaaag ggtcttgttg
     3061 aatttaaaaa tgtttcgttc atgtatccag acgcagaaga acctatatta acaaatatat
     3121 cttttacagc aaagccagga gaaacaactg cctttatagg aagtactggt agtggtaagt
     3181 caactcttat aaatttaatt cctcgtttct ttgatgttac tgaaggagaa atattacttg
     3241 gtggagttaa tataaaaaat gtttctcaac atgatttaag ggaaaaaatt ggatatgtac
     3301 ctcaaaaggg agtattgttt tctggtacta tagaatccaa cttaaaatat ggtagaaaag
     3361 acgcaacaga tgaagaaatg agaacagcag ctgaaatagc tcaagctaca gaatttatag
     3421 attctaaacc agaagctttt aaaactgaaa tttctcaagg tggaacaaat gtatctggag
     3481 gtcaaaaaca aagactttct attgcaagag caatagcaaa aaatccagaa gtttatatat
     3541 ttgatgatag tttttcagca cttgacttaa aaactgatgc agctcttcgt aaggctttaa
     3601 aatcaaaaac tgctgaaagt acagttctaa tagttgcaca aagaattagt actatcttaa
     3661 atgcagaaca gataattgtt ttaaatgagg gagaaatagt tggaatagga acacataaag
     3721 agcttctaaa aaattgcgaa gtttatgagc aaatagcttt atcacaactt tcaaaggagg
     3781 agctagctaa tgagtagaat gggaagaggt cctatgggaa aatctatgga agcaggacaa
     3841 aaagcaaatg actttaaagg gactatgcga aaactaattg catatttatc taaatttaaa
     3901 atatcaataa ttttagtaat tgtatttgct attggtagtg catcgttttc tatagtaggt
     3961 ccaaaaattt taggaaaggc aactacaaag atatttgaag ggttagtgag taaagtttct
     4021 ggaggaaacg taggtataga ttttaatgca attggaaaaa tcttaacctt tttacttttc
     4081 ctttatttga taagtgcact gttctctttt atacaaggat ttataatgag tggaatttct
     4141 caaaaagtat cctataattt aagaaaagag atttcagcaa aattggatag attaccaatg
     4201 aagtattttg atactaagac gcatggtgaa atattatcga gaattacgaa tgatatagat
     4261 actttaaatc aaagtttaaa tcaaagtatg acacagctta taacatcagt aacaactatg
     4321 ataggtgttt tgataatgat gttatctata agtggaatta tgacattagt ggcagtttta
     4381 atattaccaa tatcaatgtt tgtaatttca agaataataa agaaatcaca aaaatacttt
     4441 agatatcaac aagaatattt aggaaatgta aatggtcaag ttgaggaaac ttatagtggc
     4501 caaacaatag tgaaagcatt taatcgtgaa gatgaagtaa ttgaagagtt tgataaacta
     4561 aatgatagcc tgtataattc agcgtggaaa tctcaatttt tatcaggtat aatgcaacca
     4621 cttatgatgt ttattggaaa cttgggatat gtaatggtat caatcttagg aggttggctt
     4681 gcaattaaga aaacaattga ggttggtgac atacagtcat ttatacaata tgtaagaaac
     4741 tttacacagc caatgactca gattgcacag gttgccaatt tattgcaatc aacagcagca
     4801 gcttctgaaa gagtatttga gtttttagaa gaggaagaag aagtccaaat tgttgaaaat
     4861 gcagtttcaa tagatggttt agaaggtaaa attgattttg aaaatgtcaa ctttggatat
     4921 aacccaaaca agactataat aaatgatttc tcagtaaatg ttaaacctgg tcaaaaagtt
     4981 gctattgttg gacctacagg agcaggtaaa actacaatag ttaaactgtt aatgagattt
     5041 tatgatgtta atagcggttc aatactgatt gatggtcata atattaaaga ttttaatcgt
     5101 agtgagctta gagaaatgtt tggtatggtt cttcaagata catggttatt tagtggttca
     5161 attatggaaa atataagata tggtaagttg aatgctacag atgaagaagt tatagaggct
     5221 gctaaatctg cacatgttca tagatttatt aagacgttac cagatggata taagatgaaa
     5281 ttaaatgaag aagcaagtaa tgtttctcaa ggtcaaaaac aattattgac tatagctcgt
     5341 gctattttag ctgatcctaa aattttaata ttagatgaag ctacaagttc tgtcgatact
     5401 agaacagaag tattgattca aaaagctatg gataatctta tggaaggtag aacaagtttt
     5461 gttatagccc acagattatc aactatacgt gatgctgata tgattcttgt aatgaatgaa
     5521 ggagatatag ttgaacaagg aaatcatgag gaacttctaa agaaaggcgg attctatgcc
     5581 aatctttaca attctcaatt tgaagaagat gaagcaatgt aacaaaaaac tatcttagca
     5641 tagacatgta attaataaga taaaataaat gagggtgcct taaaatgaac tttttaattc
     5701 ataaggcact cttttgtgta tgaaataaag tgtattttta tcattttaac aatgaaaaag
     5761 aggattatct atattttgag atagccacat aattttatgt ctttacaaag tgtttatttt
     5821 attataatat gtagtaagga aaatgttgga ggtgattatc aaaatgtata tttaatttta
     5881 ttctttaaat tttattataa atagaattta attttaatag ttgatgatta tattgaagta
     5941 tatgttttta ttacttttat taatcatgca aataactact taaatttaag aatagggtta
     6001 aatataaaat gataattaca tataagttaa ttaaactaat gtatttttaa tatatattta
     6061 gaattttaat ccttcttatg atataagtag cttgttttgt attacttaga tttgtaagga
     6121 gtttttttat tgaaaaaact gcataatata tttgggagga ggtgtaagaa agtgattttt
     6181 tatataagat tgagaaaata atgcacgatt atggttatta taatagtaaa taagaagtgt
     6241 catttaagga taagataaaa agcaaaattc ttgatgaatt taattataga gccataatct
     6301 cgtgctatag attaaataaa aaatagcaga taaggagaat atggatatga cgaaaaaagg
     6361 aataacagta ggattaaaca taaataataa atctgaggac tttaatgaac taatgattga
     6421 acttgaaaac ttatgttcag catgtgatat tgatgttgta gggagtataa ctcaaaatgc
     6481 aaagcaggtt aatagagcat tttacattgg gacaggtaaa gttgaggaaa tattaaactt
     6541 aataaagaaa gaaaacatag agatagttat attttacaat gaactttcta catcacaact
     6601 aaaaaatctt gaagaaaagc ttaattgtga aattatagat agaacggcat tgatacttga
     6661 tatatttgca caaagggcaa aaactagaga agctaaactt caagtagaag tagcaagttt
     6721 aaaatatatg ttaccaagac ttataggttc aaatgaaaat ttaggacgtc aaagtggtgg
     6781 agttggtact aaaaatagag gttctggtga gaaaaaatta gaacttgacc gtagaagaat
     6841 agaagaaaag ataacatctt taaataggga gttgtatgat ttaaaattcc aaagagaaac
     6901 tcaaagaagt atgagaagaa aatcaaatct tccaaatgta gctctagtcg ggtatacaaa
     6961 tgctggtaaa tcttcaataa tgaataaact agtagatata tttaaaaact ctgaagaaaa
     7021 gaaagtgttt gagaaaaaca tgttatttgc tacacttgaa acttctgtca gaaatatagt
     7081 tcttgcaaat aacaaagaat ttttattatc tgatactgtt ggttttgtaa gtaatctacc
     7141 acatgactta gtaaaagcat ttaggtcaac attagaagaa gcatgtgagg cagacgtact
     7201 gttacatgtt attgatattt caaatccaag ctataaaagt catattaaag tgacagaaga
     7261 tactttaaaa caaataggtg cagatggtat acctatgata catgtgtata ataaaattga
     7321 tttaatagat gtagaagtat tggatagaat tttagatagt atcgataaag aaggtatatt
     7381 tgtttcagtt aaaaaagata taaatataga taaaatgata aaatgtattt gtgatagcat
     7441 atttaaagat tgtgtaagat gtaagttctt aattccatat gataaaggtc atgtagtttc
     7501 ttattttaac gaaaatacga gcattataaa tacagaatac agagaagatg gagctatttt
     7561 agatgtagaa tgtagcaata tagaatataa taagtataaa aagtatgctt tagagtaaat
     7621 tttgaaaaac ttattatagc ctaaaatata tttaatttat aatttattat aaattgattg
     7681 taaatatgat tttatgaaac ggtatagcca taatgctatg ccgttttgcc atttataata
     7741 aaaataaatt tattgacaca atagtaacta attactataa tataaagtaa ctagttacta
     7801 tttaaaatta tcaaaaaatt aaaatctaag ataaagagaa gtgtataata atggatgcag
     7861 aaagtttaat gaaaaaatat atggtagatg atgatagtag aaaacaagct atatttgcaa
     7921 gtatatttgt aatgcaaaat aaacttcaaa ctacatgtga taaattagac ccagaattaa
     7981 caatgaaaca atggttactt ttagctattg cggactctgt agatgaaact cttacattaa
     8041 ccaaacttgg agaattaatg gggtgctcaa gacaaaatgt aaaaaaacta gctattgctt
     8101 tagaaaagaa aggttttata caaattgagc aaaatgaaaa agattcaaga gctatctgtc
     8161 ttgtgacaaa agatagagtg caagagtatt ctaaaaaagt aagaggtatg caggaaaaag
     8221 tattacagct tttatttgaa gattttacag agaaagaagt ggaacagtta ttttttggaa
     8281 ttatgaaatt aagtatagga attgaaaatg tgaaaaatta tgtagaaaat aatgacgttg
     8341 gagaataagc aagtatcaaa tcaactttgt atgacatcag agaggggggt aatttatatg
     8401 aaaagtgtag tagtgattta taagagtaag tatggttcaa caaaaaaata tgctaaatgg
     8461 ctttcagaat tattgtcttg tgatattttt gaaactaaga atattaatat agaaaaggtt
     8521 atgaagtatg atacgattat tttaggagga ggtctttatg cttgtaatat agcgggaatt
     8581 tctttcttaa aaaaaaatta taaagatttg cagaaaaaaa atttagtagt atttggcgta
     8641 ggagctgctc catatgatga tgaagtaata aagaaattaa gagaagtaaa ctttaaggat
     8701 gaattaaaca aagttccttg cttttattgt cgtggggcat gggatgagac aaaaatgtct
     8761 tttatagatt atactctttg tagttttttt aaaaaatcta tagctaaaaa agaacgtcaa
     8821 ggtcttaaac cagcagaagc acctttattg tctggagaag cctttgattg gtgtaataaa
     8881 gaaaatttaa ctccaatact taattatata agaaaacttt aagaggtata tatttataat
     8941 tatttattat ctaaagttag atttcataga aacttactag acattattta taaaataata
     9001 ttattaaaga tggataattt aattgtttca ataaggttat aattttaaaa aatgtttatt
     9061 ttaaaataaa ttattttata agcttactta tacttaataa ggggcttttt ttattggaag
     9121 atttatgtta tattgagatg aatttattat gatataaaaa ataatgttag gataaattta
     9181 aatctttttc taaaaatgta ttaatataat tcttaaagaa aggattttta acaatggata
     9241 taaaagagtt agttaaaatg caaagaaaat attataatac aggtaaaaca agagatatat
     9301 cgtttcgtat agaacagttg aagaaactta agttagttgt atcacaaaat gaagaaaaaa
     9361 tacttttagc actaaagaaa gatttaaata aatcgaattt tgaaggtttt atgacagagg
     9421 taggcatgtt ttatagtgaa ttaaactttg ctataaagaa tataagaaaa tggagcaaaa
     9481 taaaaagagt taaatcaagt atggttaatt ttccatctat atccaaagtt gttccacaac
     9541 cttatggtgt tactctcata atgtcacctt ggaattatcc ctttcaatta gcacttatac
     9601 cattagtttg gtcattagca gcagggaatt gtgttatatt aaaaccttct gaatattctg
     9661 tgtcaacatc tagtgtagtt aaagacatag ttgaaaatac tttttcaaaa gaatatgttg
     9721 cagttgttca aggaagtcaa gaagaaagtg aaaagttact attggaaaga tttgattata
     9781 tattttttac aggaagtact aatgttggta aaataatcat gaaatcagca tcagagcatt
     9841 taactcctat tactttagaa cttggaggaa aaagtccttg tatcatttta aaagatgcta
     9901 atatagacct tactgccaaa agacttactt ggggaaaact aataaatgca ggacaaacct
     9961 gcgtggctcc agattatgtt ttagtgcatg aagatagaaa aaatgagtta atagagaaaa
    10021 taaaatatta tactaataag tattttggag ataatccatg taataatgag caatttccta
    10081 aaatcataaa tcagagacat tttaatcgga tattatctct tattgataaa gataagatag
    10141 tctatggtgg aaattataat aaggagacat taaagataga gccaactata gtagacaatg
    10201 ttaattggga tgataatata atgaaggaag aaatatttgg gcctatattt cccattttaa
    10261 catataaaga tttagatgaa gtaatacaaa aaattataca aatgccaaat ccattggcac
    10321 tttatatttt tacaaaaaat aagtacctag aaaataaact tttagaaatg attccagcag
    10381 gcggatgttg tatcaatgat acagttactc atatagctac gaattactta ccttttggtg
    10441 gtattggtga aagtggtatg ggctcatatc atggaaaagc tggattcgat acatttactc
    10501 actataagag tgtgttaaaa aaattaaatt tggatgtccc tattagatat gctccatacg
    10561 ataataaatt aattaaggtt cttaaaaaga taatgtaggt tatattgtag aataataaat
    10621 ataaataaaa ttgagtattt gtattctgaa tatattttat ttttaatttg gtatatttgt
    10681 tataaaagtg gtgattttgt gataaaattt aattatatag aaataaggag gaaaaaatga
    10741 aaattaattg gaatacaaaa tacacaacaa tagcaattta tacatttata atagctgcta
    10801 gtagtattat attttatcta gtatcatcac aaattgatgt attttctaat aatttagatg
    10861 ctatatttac aacattacaa ccttttataa taggatttgc tattgcatat cttcttaatt
    10921 ttattttaaa gttttatgaa gacagaattt ttataaaaag tgagaaatta aaaaaactaa
    10981 aacaaagttc aaaaagaggc ttgggtcttt tattaacata tgcaacagct acattgatac
    11041 tttacttatt tatgcatttc gtattgccac aagtaattga gagtattgtt ggactagcaa
    11101 atgatatacc tatgtatgta aacaatgcaa ctaagcttat tgataaatta atgactgatt
    11161 taaatcttga tgagcaatac tttaatttgg cagttgataa gtggaatgag tttgttacat
    11221 atattataaa gtttgtaaca gatttaatcc caatattagg aagtatgtta aagaatgtag
    11281 cctctagtat atggaatatt gtactaggat taattgtttc agtatactta ttaattgata
    11341 aagaaaaatt ctatggatta agcaaaaaaa taacttatgc agtatttaca gaaaaacaag
    11401 ctgccagaat tttagaatta actcatagaa gtaactatac atttggaaga tttttaggtg
    11461 gcaaaatatt agattcattc attataggta ttctaacatt tgtaatactt acattagtta
    11521 aaatgccata tacattatta atatcagtta taattggtat tacaaatatt atacctttct
    11581 ttggaccttt atttggagct ataccatcta ctctaatagt gatgtttgta tctcctataa
    11641 aagctttctg gttattgttg attatattaa taatacaaca gatagatgga aatattatag
    11701 gacctaaaat acttggagat tcaattggta tatctgcatt ttggattttg ttctccttat
    11761 tggttgcagg aaaattatta ggttttattg gaatggttat aggagttcca atgtttgcag
    11821 taatttattc tataattaag gatattgttg aaagtaaatt ggacaaaaag ggattaccga
    11881 cagatacttc cgattacatg tagctaaaaa atattatgta taattaaaaa tatataaatt
    11941 aagcaatatt taaagcactg agaaagttaa actcttggtg ctttttagat ataaaattat
    12001 tatagaagag gtgttttttg tggcatttat agaatgtaaa tttaaatcta aatatactgg
    12061 aggagaaact gatataattg taattttgcc tgtagcaaat ggaaaagaac tttttagtgg
    12121 taaagagata tatgattttg aaggtaaatt taaaacatta tacttatttc atggtttaga
    12181 agatgaccaa agctcatgga ttagatatac taatgtagag cattatgcta aaaataaaaa
    12241 tatagcccta gtaataccaa gagtagaaac tagtttttat acagatatgg cgtatggaca
    12301 ccaatatttt acttttgtaa gcgaggaatt acctaaattt gttagagcta tatttccttt
    12361 atcagataaa agggaagata actttgtagc tggtatgtct atggggggat atggagcttt
    12421 aaaattagca ctttcaaaac caaaagagtt ttcggcagtt gcaagttttt ctggttcgcc
    12481 tgatatgatt catgagttag aaaatcaaca aatagaaacc aatgcagaca ttttatttca
    12541 cgattttggt agaccagaag acgctagaaa tagtgagaat gatttacttt acatacttaa
    12601 gaaccttaaa gaaagaaatg aagatattcc taaaatttat caattttgtg gtgatagaga
    12661 ttttttatat aaaaataatc agatgtttaa aaaatatgca gagtctctgg gtgtagatgt
    12721 tgaatatgaa gagtgtgtag gggggcatga atggcgtctt tggaatttat ggataaagaa
    12781 atttatagat ataattgggt agtacactta tggtattaac aggtatacta taaaatatct
    12841 ttaaatatga taaagactga aatcctaaaa tcaaattatg attttaaaat ttcagtctat
    12901 aagaatttaa taaaatttta ttaagttctt acacgagtta ttattggagt aaaattgtca
    12961 actatatcta tatagtattt actcaattcc tctaaaatct cttcgcataa atccgtacta
    13021 tgaccaagat taataagaaa ctgttttgta aaatgcttta ttacagcttg agaagatata
    13081 tcgtacttgt gtgaagtata aactctaatt atttcaggtt tcatagcaag tataccaata
    13141 caagaaagta ttaattcatc atgttctata gattctttat cattaacata tcttttcatg
    13201 accatttcgg ttacacttct ttgatagctt aaaatagctt cttcataagc tatatccaaa
    13261 taaaaatttc tatatgcttc gttttttaga aggaaacaaa ggtcagcatt catagcaaga
    13321 aagaacatca tcatagtacc ttcttcatgg tagttataga ttaaagactg catttcattt
    13381 cttatatctt catatattat agctcctatt tcgcttttac ttgagaagta atagcttatt
    13441 agacctaaat ttatattagc tctttctgca atttgcctag ttgttgtctt atgataacct
    13501 tgctcaaaaa ataattctct agcagcactt ataatactag cttttgtttc tttgcccttt
    13561 tctgattttg acatatttac tgtgtatacc tctcttttca atcttttttt gaaaatttgc
    13621 taactataaa tattgtaata gaaccaccta ttataggaac caaaattctg tcaaatacag
    13681 taagaatacc aatcatattt aataatgcca atataacact tactataaca gcatagatag
    13741 ctcctttttt tgtagcgcct ttccagcaaa gaccaattac aaatggtgca aatattacac
    13801 ctgtacataa tggagccggc caaaacaata attctaataa actatcaaat ttaagtgcta
    13861 tgattgcacc tattatagct gtcaaagctg atgcaatttg agaatacttt agagtatttt
    13921 ttaaatcatt aaattctata ttaggatgta ataatttgtt ataaatatct cttgatataa
    13981 tagcactcat tgaggtcatt aatgaatcgg cagtagacat tatggcagcc aatatagcag
    14041 ctaagaataa tacagatatt aaaggtggca aagtagtcga tatcatttga ggtaaaacct
    14101 gaacagatga tatgtttgga aataaactac caccaatagc tccaattatt cctataggga
    14161 aggcaagaaa taatagtata aatcctgcaa ttacactact tttaactgca tttttagcat
    14221 tatcagcaca ttgatatctt aaaaaacttt cataagaaaa tattgagcct aaaactaatg
    14281 gtaaaactgt atacataaaa tcactaatcg atttatttcc tggaaagaat ggttctttta
    14341 ccattgattg taacataagt aaagggttgt cgccaactaa ttttaagctt atataagcta
    14401 ctattggcaa aaacactata caaatagcaa gttgaataaa tgctgatact gcaactcccc
    14461 acattcctga tgtataagta tatataatta taactataac tcctataatt acagctatat
    14521 cataaggaat accaaatgca gtagatacag aaccaaaaga aattaattga ctacccataa
    14581 tagctagtat agatattggt gttacaagac tttgataagc tcttaaaaat acactatgac
    14641 catatctagt ttcaatataa tcagcaggtg ttatatcaca agataagctt cttaattttc
    14701 ctgcgaaaaa ggcatttata aagcaagcta aagctgcacc tatagtagaa tacattccaa
    14761 cccaaagtcc tctttcagct ccccattgaa ctccaccaac taagcaccct cctccaaaag
    14821 atgtagcagc aatggttgca gctagtatag gcaaaggaag atttctacct gcgattagga
    14881 aatcggatgc tgttttaact ttttttgaaa aataaaaacc aatccatatg tatattgcac
    14941 acgtaacaat taaaagtaac atagtctttt ctcctttata aaatatttta ataaaatata
    15001 taaaatatat ttaaaatata ttttatataa aagtagtacg atatttgttt tattggtttt
    15061 agattaatat agctataata atttatgata ttagatggaa attacgtaaa aatagaaaat
    15121 tgaaaattct gaaatttttg catattgata tttatctcat agattctttt ttgtaattgt
    15181 aacacgcttt tatttttaaa tcaatagtac atgtataaaa ataaaaggaa tctaaataag
    15241 aaaaagatat ttttaatatc tggatgtagt atagaaatat cttgaataaa ttattcttga
    15301 ataaaattat aaaaatttaa aatcactaga aatatgataa aataatttaa aatacgcatt
    15361 tcaatgacat ttcaagacaa gaaaataata aaaaacaaat ctaaattaag cctaaatagc
    15421 tttttagtta attttagtag taaaaaataa aacttaaaaa gtgtttgaca attatgaatt
    15481 ttaagaatat aattaaatta aaattataca catataaaaa tatactcctg aatcaagaat
    15541 gagatattta agattcaaaa tatatattat tatacgtgaa taatgaaaag taagaaaatt
    15601 ttataaggga ggggtagatg tgagtagtca agaaagcaaa ccaaaaggaa atcttatatc
    15661 aaattttaga gatgatatga gagaccctaa gaaaagagca atatacacat attcaagttc
    15721 tataaactta gcgtacaatt ttataggtta ctttgtatca actgttacaa atattttttt
    15781 aactgatgtg gcaaaacttg gtgtaattat ggcaggtggt atgcaaatta tacaatcttt
    15841 cataaaaatt gctgtagctc ctataacagg tacagtattt gacaaacaac cattcaaaaa
    15901 aggaaagtat tatccatggc ttagatatgc accagcagcg ttagcattaa catatggaat
    15961 atttttcata gttccattaa tgaaaataag tccagcatta cttttacctt tgatgacagc
    16021 tttattatta atagcatctt gtgctcagca agtagttttc actataattt atgctattta
    16081 ccctgtagtt gctaagacac ctagagaccg agttataggc tcaactacta ctaatatatt
    16141 taaagaagtt ggtaaattct tagtaggttt ttcatatccg ttattattag ttttatttgc
    16201 agatgtatta ggtggagaag gaatgggtta tttaggtacc tacttattct ttgcagcagg
    16261 atgcctttta gtattttggt tttcttcaac agagataata aaatctggag cagaagaaga
    16321 agttcttcaa aaagaagaga agccaaagat taaagcaagt gaaatggcaa aagctctatt
    16381 cactaatgta ccacttatga tggcattttg tttagaattt cttatatgta taagatctat
    16441 aggattagga cctttggctc catattattt taaatatgta atagaagatg aacgtggatt
    16501 agcagtattt ttatcaatca tgcctttggt aagtgtagca ttcatgtttt tcgcaccagt
    16561 gtttataaaa atctgtagag agcaaaaact agcttcaata atttcttttt ctatatgtgc
    16621 actatgccac ttattggttg catggactcc ttgggggaaa actactttag gagtaactat
    16681 gttgctggca attggtggag gtttttcaaa tgtagtatca ataataaatc ttaatttctt
    16741 tgccggttct tgtgattatg ggcattggaa atcaggaaaa gacttacctg gcttaagtat
    16801 gtcactatat ccagttgcaa tacaagtagg agtattactt gcaactacta taagaacagt
    16861 tttaatgaac tcaatgggat atcaagctga tatggtagtc acagaagcag ttaaatcagg
    16921 ttttataaat atgatttctt attctatggc aataccttta ataatagctg ttgttatagc
    16981 aatactatat ccagtaagtg acaagaaatt aaaccaaata agagaagagt taaatcaaag
    17041 aaatgcttag ttaaaagaaa gttaagtaga tggttaattt aagctattaa agtaagtaga
    17101 cgcaatagcg tttatataaa tcaaaataca tatacagagg gggcttttaa aaatgataga
    17161 aaaattattg agaaataccg taaaagaatt acatcaatat gttccaggtg aaccaataga
    17221 aaaagttaag gaaaaatatg gtgtaaaaga aataataaaa ttagcttcaa atgaaaatcc
    17281 tctaggacca tcaccaaaag caatagaagc tatgattgaa atgctaaaac aaggtcaact
    17341 ttatccagag ccagaagcta acgaacttag aagaaaatta gctgaaaagc tagatttaaa
    17401 accagaaaat tttattgttg ctaatggtgc ggataacgtt atcactctaa taggtgaggc
    17461 ttttataaat agaggagatg aagttatata ttgtaaccca acatttccat catatagaac
    17521 tgcaactata aaaaatgaag ggataccagt agaagtgcct ttaacagaag attataagta
    17581 tgatttacaa ggtatattag ataagattac agataaaaca aaattaatat gtgtatgtaa
    17641 ccctaataat ccaacaggaa caattgtgga tgataaagag ttagaagaat ttttaaagaa
    17701 agtccctgaa aatattataa ctatattgga tgaagcatat atagaatttt taacagttcc
    17761 taattatgtg gatggactta agtatgtaag ggaaaattat aacgttatag taacaagaac
    17821 tttctctaaa atatatggtc ttgcagggct tagagtagga tatggtattg ctaaagatga
    17881 gataataaga actttattta cagtaaaaga gcctttctct gcaaatcgtg ttgctataag
    17941 tggagcaaca gcagcacttg atgatgaaga gtttataaaa gaaacatatg aattaaatag
    18001 agttggaatg acttacttta aagaagagtt tacaaaaatg gggtttgatg ttgtagattc
    18061 acaatcaaat ttcctttatg tagatatgaa aacagatata cctaagttat ttgaagactt
    18121 gaaaaaaaga gggtttgtaa taagaccaag tgctacacat gcacgtgtaa gtattggaac
    18181 tatggaagaa aataagaaat ttgtagcagt tttaaaggaa atattaaata ttaaaggaga
    18241 gccaagtatt ggataataga tagaaatatt atgaaacggg gtgtagatat gaacttaaaa
    18301 ataaacgcag agagatgtaa aagttgtgaa tactgcgtta tatcttgtaa aaaaggagca
    18361 ttaaaaatat caagtaagat aaataaagaa ggttatgctc atgtagaagt tgatgagagt
    18421 aaatgcatac tttgtggaat ttgctatcag gtgtgtccag ataatgtttt tgaaataatt
    18481 aaagaaaaag catgtcaaga ggcttagaag gagttgggat aatatgaaaa agatgtggaa
    18541 ggggaaccac gccattgcag aagcagccct aagaggaggt tgtgaatttt atgcaggata
    18601 tccaattaca ccacaaacag aggtaatgga atttttatca catagaatgt ctgaacttgg
    18661 aagaactttt atacagtccg aaaatgagat ggctgctata tatatggtat atggagcata
    18721 tgcaagtgga atgaggtcta tgacgagttc ttcaggacca ggaatatctt taaaacaaga
    18781 agggatttct tacttatgtg caaatcatta cccttgtgta atcgtaaatg tacagagatg
    18841 ggggcctggt cttggctcat tggactcagc acagacagac tatctaagag atactagagg
    18901 gggaggaaat ggagattatc atttgatagt ttatgcacca aacagtattc aagagactgt
    18961 agatttgatg tataactcat ttgatgtagc ggaaaaatac agagtgcctg tcgaaatttt
    19021 gacagaagca gctttaggtc aaatgatgga accagtagaa tttccagaat ttaagaagag
    19081 agaaggagat ttaggttgga cttatgatgg aagtaataga gaccatgcaa aggttgcaga
    19141 taaccaaaag ccaacttttt gtatggagaa acgtatgaga ataactgaaa atgaacaaca
    19201 atgggaagat tatcaagtag aagatgcaga atatgtgttt gtagcgttcg gtataccatc
    19261 aagaacaact atgaatgctg ttagaagact tagagaacaa ggtgaaaaag ttggaataat
    19321 aagaccaata acagtatggc ctttcccata taaagcattt gaaaaggtaa gtaaagatgt
    19381 aaaaggattt atctcagtag aatcaacaga cacaggtcaa ttagtagaag atgttgcttt
    19441 agcctcaaag aaagtatgta aagaaaatgt acctgtgtat ggtttattta gtggaaatca
    19501 tataccaaaa acattgcaag taatggacac ttatagcaaa ataaaatctg gcgaaatcaa
    19561 ggaggtgttc taatatggct acagaaaaat taacacctag cgttgtttca ataccaaaca
    19621 agttttgccc aggttgtggt catggaatag taaatcgtat aatagcagag gtaatagaag
    19681 aacatggata tgaaaaaaat catgtattaa cattaggagt tggttgtgtc tgcaatatga
    19741 attttagctg gaatggtgat aagatgcaaa ctgcacatgg tagagcttca tctacagcta
    19801 taggagttaa agtagcactt ccagatacat tagtaatgac ttaccaaggt gatggagatg
    19861 cttatgttat aggtctttct gaaactttaa atacagcata tagaaatcat aatgtgactg
    19921 tatttgtaat aaacaataat aattttgcaa tgactggtgg acaaatgtca tggaccacta
    19981 tgccgggtca agtcacaaca acaagtgtaa atggaagaga tataaagact actggtagtc
    20041 cactgaaagt tcctgagatg gtggcaaact tctttgatgt agcatatgta gcaagaggtt
    20101 cagttcatag cccaaaggaa ataattaatc taaaaaaata tataaaaaat gcaatagaag
    20161 ctcaattaaa tggagaggga tattccttag ttgaaatatt agcaccttgc ccaactaact
    20221 ggggtgtatc actagagaaa tctatcaaat ggatggaaga agaaatagtg ccatattatg
    20281 ctcttggcga atttaagcaa agggatggtg aatagttatg gaaaaagagc tagtatttgc
    20341 agggtttggt ggtcaaggag ttttaactct tggtctgatt gtagctgagt cagcacttga
    20401 attggggaaa caagtaactt ggatgcctgc atatggtcca actatgagag gtggaaaagc
    20461 ctatagtgta gtaaagtttt ctgatgagag tataggtggg cctgatatgg aagaaataga
    20521 tgttttagta gcaatgaata aaccatcttt agattatata aatttagtta aagaaggtgg
    20581 aacagtagtt attaatacat ctgcaataga tgagaatgta acattaagag aagatataag
    20641 tgtagttaaa ataaattgtc aggaattagc tcaaaaagta aacaatccaa aagcagcaaa
    20701 tatagtagta cttggagcat taattgctaa aactgggtta cttgaaaaag aattagcttt
    20761 aaaaactatg tgtgatttct ttgaggaaaa aggaaaagga aagtttaatg ttcaaaatga
    20821 agcagcattc atggaaggct ataataacgc catttgataa attaccctta tcttaagtga
    20881 tttatctcaa gatttaataa tctttagtgc caagagaaac ttcatcttga gataaaattc
    20941 acttaaaatc acaactataa acatatagga gcgtgaattt atgagtttgg aaaaacttat
    21001 tagaccaaaa agtattgcta tagtaggagt gactgataaa cttggttttg gaagaagtgc
    21061 agcacttagt atagtaaaaa gtaaggaaac agatagagta tattatgtta atcccaaaag
    21121 agaagaattg tttgggagaa aatgttataa gatgatacaa gaagttccag aagtagtaga
    21181 ctgtgtagta gtatgtacgc ctagaaatgt agttccatct gtattaaaag attctggaga
    21241 gttaggaaca aaggcagcag tggtatatgc tagtggattt gcagaggaag gtacagagga
    21301 aggtacagat ttagaaaatc aacttataga aatatcaaat acatacgata tgaaaatatt
    21361 gggtccaaac tgcatggggt tgctaaattg tatagataag gttaatctat gggcaggagg
    21421 ttctaaatgg gctttagata ctaaaaaacc tggtatagga attgtaggtc aaagtggatt
    21481 tataactgct gaaattgttt caagtgatta ttttaatata tcttatggtt tttcaacagg
    21541 aaatggaaat atagttacac tagaagatgc agtagatttc cttgtagatg atgattatgc
    21601 atcagtaata gcaatttacc ttgaaggttt aaaaaatcct caaaaattta tagatgcttt
    21661 aaaaagggca gcacaaaaaa gaaagccagt aataatattg aaatcaggaa ggtcagaaaa
    21721 aggtgctatt tctgctgcct ctcatacagg aaatttagct ggttcgagta aagcttttga
    21781 aagtattttt gaaaaatatg gagtaatttc tgtggaaaat ttagaacagt ttatgtgttt
    21841 agcacaagct tttagtgttt tagatggtaa tttacctgca aattctaatt ttgcagcaat
    21901 aaacttctca ggaggagaaa atactatttg tgcagattta gcagaagaaa atggtgtaga
    21961 acttgcagaa atatcttctg aaactaaaga agaaatgaaa aaatatcttc caggatttgc
    22021 aacacctaaa aatccactag atgctacaac agcattattc catgaaaagg atatgatagt
    22081 aggtttatta catacctttg aaaaggatga tagtgttgga tttactatgg taggtgcaaa
    22141 tataagagat gaagaaaatg aaatgcatga aaccctttgt aaagctgtaa gtgaagctag
    22201 agaacaagga ttgaaaaaac ctgtgtttgc agttcctaca cttgaaggaa atagatattt
    22261 agattatagg actagattag aagataatca agtgcctata atgtcatcag ttggaactac
    22321 atttacttgt tttaataaaa tggctaagtt tatagattat gattattcaa aaagaacttt
    22381 agaatttaaa gctgttaaga aaagagagtc aaataatgta gtagcattat cagaattaga
    22441 tagtaagatt gagatgaaaa aatatggagt accagttcca ggacaaggta atacaaaaag
    22501 tattgatgaa ttagatgaaa tcttaaaata tattaagtat cctgttgttt taaaaataaa
    22561 ttcttctgaa atattgcaca aatctgatgt tggaggagtt aaaataggaa ttaagaatag
    22621 agatgaggca gtagatgcat ataatgagat tttaactaat gtaaaaaaag caaaaccaga
    22681 tgctaatatt gatggtatat tagttcaaga aatggtagaa agtggtatag aaattattat
    22741 tggtataact aatgatgacc aatttggacc aatgttatta gtcggtttag gaggagtatt
    22801 tgtagaggta tttaaagata ctacattata tccattacct ataaatcatg atgaagctat
    22861 tatgatgctt aaaaaactaa aatcatttaa gcttttaaat ggctatagag gaagtgagcc
    22921 ttgtgatatt gatgctcttg cagatatgat ggtcaaatta ggaaaatatg cttatgaaaa
    22981 taaggatgaa gtcaaggaaa tagacttaaa tccagtgttt gtatatccta aaggaaaagg
    23041 cgtatgtgca gtagatgcct taatagttaa atataaatag tttataagtt ttggtattca
    23101 accataatta aagcaccgac tgaaaatcac attttgtaag ttagatagtg tgattttcag
    23161 tcaccccaaa tttaatttaa aaatatttta aaatgaaagt atagttttga gtttaattgt
    23221 gaaatagcac tgtataaaca ataaaatact acgtataaaa cgaataataa aaggtgtttt
    23281 aatgataaga atcaatcttg attttcatta aaacaccttc tttattatat taaaaatttt
    23341 taaacgttat attgtcacag gtgggtttgt tggagctgca tatgtacgat tagcaaattc
    23401 ttggtcaaca aagaatagac caccctctcc agcaagttta acacgtttta tattgtcttc
    23461 acaatttgtt tcttcttctg cttgttcaga tataaaccaa agtaagaatt gagaagttct
    23521 aaagtctgat tcagagtttg ctacagctgc taagttgttt attaaagctg taaccttttt
    23581 ttcatgagct aacgtacgct caagaatatc cattgcagaa gtaaagtctg aatctggcat
    23641 tgggatagca tcaagctgaa cctttcctcc tacattatgt aagtatttgt aaaaaaacat
    23701 agcgtggtct gtctcttctt tatattgaac ataaaaccaa ttagaaaatc ctttaagtcc
    23761 ttctgcttca aggtaagaag acatagaaag ataaagatac gcagaatata attcatggtt
    23821 aatctgctca ttaagtaatt tttccatttt agctgaaatc atttttatac ctccaaattt
    23881 taaatgctct tataaaatat aataatatta aatggaaaaa tattcaataa aagtgtttaa
    23941 atattttaca tatttaataa aaatttatac taccattaaa aaaattataa cttacaatgg
    24001 ctatagagcc aattaatggt gcatttgctc caaaatttga atgccttaca cttatttttt
    24061 tatatttaga aaaacttgct gaagcagtca atttttttaa taatgtattt tctataaatg
    24121 taccaggtat attaaagtca tagcctatta ttatagaact acaatcaatc aatgtaagtg
    24181 tattaactaa tgcatatgat acgtatgtac aaaattcatc aagcaaaaac atggcaagac
    24241 tatctttatt atttgcctca tctattaact tgactaaaga aaaatcttta cagttaatta
    24301 atggggagtt aggataaata tggctcaatg attcaattct tttaattaga ttactgacac
    24361 ttgtataata atctaaacat ccattgttac cacaactgca caatggtcca ctaaaattaa
    24421 ttgatgtatg tcctatttct ccactttgtc ctaggttgcc agtatgaagt ttattttcta
    24481 gaactagacc agctccaata ccattcatta tgtgtaggta tatataattt gatatatttt
    24541 tacctaaacc atacattttt tctgctaatg cacccgaatt agcatcattt atcaaaaata
    24601 ttggaaaatc agacatttct tttataaaat ctactatatt taggtttgat acatttccaa
    24661 agtctggggg atttagtatg gtaccattta tatcatctac tggacctatt gaagaaatac
    24721 caattccaat tatatctctc ttgttgattt tcattatttt agtaaacatt ctttttatta
    24781 tatcttttaa aacatcattt gatagacatt tagggtaagt ttcagaaagt tgttttacaa
    24841 tattaccttt taaatctgaa ataattacct tacatatatt tcttcttatt aggattccac
    24901 aaatacaagg cgatatatta gaaatatcta ataaaatagg tttacgacct gatgaatgtg
    24961 catttaaagt tgatgactct atttccctaa tcatattttc attaataagt tcagtaacta
    25021 gatttgataa agtcatttta gtaagtcctg tagacttagc taaatcaact ctggacatag
    25081 gtgtatttgt agaaagtaat ttcaatatta ttaacttatt tttaattttt acatctttga
    25141 tgttagaacc ttgtttgtta ctcatcataa atctccttaa ataaagttaa gtgttttatt
    25201 tattttcaag tatactatca ccttataata gagtaacatt tttttacttg aaaatatcat
    25261 taattagaat atatcacatt atatatcata aaacatataa aaaaatgtta gaattaaatt
    25321 aaaagtgaaa agtagattga tatataaata gtaaatactt aattaaaaaa agataatgat
    25381 agcaataatt attgttacca agaatctact acttcaagtg ttaccttagg tatttaagtt
    25441 gatagtggtt tgcacgtaat aaacttgatg taatatatat tcttaataat atcgataaaa
    25501 gatttactta aaaataatat agattatgta aacatataat ctatttattg tatacaataa
    25561 aatttcattt tgtaaaacag tgaattaaat atgtaatata gatatcgatt tttattacaa
    25621 attgttacta aatataggta cattagaaca aaaatctagt aaattgtaac taaaatgtaa
    25681 atttttcctt taatctatac aatattatgg aaactttttg taatttatga tataataaca
    25741 aatatataat tattaaatta taataaatga ctatagcgta gatgtaatac tatgttatag
    25801 tcatttttga attaaacttg atatatcaag ggggaagaat atgagaacaa ttagaagagt
    25861 tttagcatta ggtttaacat tagctatatt tctaataaat gtacctaatg tagatgcatt
    25921 aacatcagat acaattaaag gtaacaatat atatgagacg gctggattaa tagcagataa
    25981 aaagagttat gatacagcaa ttatggtaaa tatggataat tctatagcag atggtctttc
    26041 agcaagtggt cttgcaggtg ctgttgatgc tccaattttg cttgcacaaa aaaataagat
    26101 accaaatgaa acaaaacaaa gattaaaaaa tgttaaaaag atatacataa taggtaaaga
    26161 attatcaata agtaagtcag tagaaactga actaaaaaac acaggggcac aggtaactag
    26221 attgggtgga gatgacagaa taaagactag ttatagtgtt gctaaagagg taaatggtat
    26281 caaaaaagtt gatgaagtga tattaactaa tgcatataaa ggagaagcag atacaataag
    26341 tgctgcaccc gtatcagtaa gagatatagc tcctatagta cttacagatg gaaagagtgt
    26401 gcctttttca acaagcaatg taaaaacata tgcagtaggt gggagtatat caatgagcac
    26461 tagtttagtt aataaaacta atgctaaaag acttggtggt tcagatagat atgatacaaa
    26521 taagaaagtt ataaaagagt tttatccaga tgcatcagaa ttttatttga gtgatggata
    26581 tgatttagta aatgcactta caggttctac aattgctaag gaaaatccaa ttgtattggt
    26641 gtcagaaagt agtgataagt ctatattagc aggagcagat aagattacta gattaggttc
    26701 aataagtgac agtgtgtata ataagtgtgt ttctgctgca caaaataatg gcgattcgtc
    26761 tacaaaaggt gagtcaccta tgaaaaatga gacaagcata ttaggtcagc caacagctag
    26821 tttagaagcg tgcttaaaat gggcaaaatc taaaaaagct aatgatttat ttatagagtt
    26881 aataccaata ttatatgata ctgctgttca ggaaggtgtt aatcctgttt tggcagtagc
    26941 tcaatctgca aaagaaactg gtttttgtaa ttttggtgga gtattagatg catcatttaa
    27001 gaatccttgt ggacttaaaa cttctgtagg tggttctgat actgataaga atgcccattc
    27061 aagatttgat acttgggaag aaggaatatt agctcaaatt caacatttat gcttatatgc
    27121 aggacaagat ggttacccac tttcaaatcc agtagaccct agacatgaaa aatctttatt
    27181 tggtaaggct aaaacagttg aaagtttatc taataattgg gctggaggtc aatatggaca
    27241 agatttagta agaatgatgg gagaaattga ggcaacaaaa taattgaaga ttatcaaata
    27301 tccaataaat aaggattgat tattatgaaa aagagtaata tttttagtat catatttcct
    27361 acaatcataa tggtgctaat gtttttaact tttgctacag atatatttaa tattccagat
    27421 attcaatcta aaagtatttt tgttgtggga atggttttga tttttccaat ttctttttta
    27481 atacaaggga taatttgtgt attaaataag actaattgga ttttatctct tattgtgtct
    27541 ttagtaactt atatagtatt aatgtatata tttttaaatg attctgcata tatatatgtt
    27601 ttactttata cagcttttta tatgattgga catataacag ctaaactcta ttacaaaatt
    27661 aagactttta aaaattaaat tgaagtatat aaaagtaaca ttaagagaag tatccttaat
    27721 gattttctaa aatcagaaat aggtgcttct cttttttgta aaaataaaag tatgtaaata
    27781 aaatttaacc attataattt tcttttaaca aatgtataca ataaacttgt tgtataatta
    27841 agatagataa aataaaggga gggataatat gaatttaata gataatcata ttcatactaa
    27901 tttttcaagt gatggaaagg attccatgga agatacaata aaaaaagcta taagtattgg
    27961 tgttagatat ttgactttta cagaccattt agaacatgat gaagatagag gattttgcat
    28021 aaattataat gactatgttc cagtatttaa taagtttaaa gaaaaatata aaaaggatat
    28081 agagttatta ctaggtgttg aagtaggtta cagaaaacat ctaaaaaatg aaatagaaga
    28141 aataataaat tctaatcctt ttgattttgt attgtgctca actcatacaa ttgacaatgt
    28201 acctgttcca tcaaaggcgt attttaaagg tcttagcaaa gaagatgcgt attataaata
    28261 ttttaatagc atacttgaaa ctaatcgtga atttggagat tacaatatat atggtcattt
    28321 ggattatata tctaggtatg gaatatattc agataataga gttatataca atgactttaa
    28381 agatgttatt gatgaggtct taaagtcaat aatcaataat gggagtggta tagagctaaa
    28441 tacttctggt tatagatatg gattaaatgc tatacatcca aatgaagata ttctaaaaag
    28501 atataaagaa cttggaggat ttatagttac tgtaggttct gattctcata gggtagaaga
    28561 tatatgtaaa gattttgatg tggcctatga tatgcttaag tatcttgact ttaaatatgt
    28621 atctttattt aaagaaagag aaacttattt tgtaaatata aaaaaagtta aatctaacaa
    28681 tatagcttag agtatgtttt gaagtaaatt aatggatagt taaaaagtta atagttataa
    28741 tattgtatcc tctagaaaaa tactagaggt ttttattttg ctaaaataac taaatagaat
    28801 taaatttaaa tagtatagtt tattttaaat tgaatagttt attgttgata tattttacta
    28861 ttatatattt ttattgtgat ataatagtaa aatatattaa cctatcttta gattatataa
    28921 attattataa aggagggaaa ttttaaaatg tttaataaaa ataaagaaaa tataacttta
    28981 agtaatcaaa tcaaaggaac aattcaaaat agtttaacaa aagaagctat attacatata
    29041 ccaatgagca attatgccta tggttatgat agagaaacac tacatataag acttagaact
    29101 aaaaaaaatg aagcgaaaag agtaatttta cgaataggag accaatatgt gtgggataaa
    29161 ggaggtgcag gaggaggaaa tttaaatgca tctggagttg gttggtctgg tggaacaaat
    29221 atagtaatga gtaaagaagt agaaactgaa ttatttgact attggatagc taagtgtaag
    29281 cctttaaata aacgctcacg atatggtttt ataatagaag gtcaagaaga aaaactttta
    29341 tttacagaaa aaagaataat agagttggga aatgaaaatg atgaaaagga attatgtgaa
    29401 ataggtaatt tttttggata tccatattta aattatatag atatacctaa agtgccaaat
    29461 tgggtgaaag atactgtttg gtatcagata tttccagata gatttgcaaa tggtgacccg
    29521 tctataaacc cagaaggagt agataaatgg ggagctattc caaccagaga taattttaca
    29581 ggtggagatt tacaaggtgt gatagaacac ttagattatt tgagtgattt gggaataaac
    29641 ggaatttact tttgccctat tacaattgga aaaaccaatc atagatatga tacggtagat
    29701 tatatggagg tagaccctac attaggagat aaagagactt taaaaaaact aatagaagaa
    29761 gcgcataaga gaaatataaa aataatgttg gatgctgttt ttaatcatat aggatattat
    29821 tctaaacagt ggcaagatgt agttcaaaat aaggaaaatt ctcgatataa aaactggttt
    29881 tatataaaag atatgagtaa aattgatact ccaatagaac agatagatga aaaaaatata
    29941 ccttatgaaa cctttgggtg tgaaaaatat atgcctaaac ttaatacaga aaattcagaa
    30001 gtaataaaat atttattgga tgtaggcaag tactggatac aggaatttga tatagatgcg
    30061 tggagattag atgtttcaaa tgaagtagac catgtttttt ggagaaagtt tagagaagaa
    30121 gtcaaaaaag taaaaccaga catttatata ttgggagaaa tttggcatgg tagtttacca
    30181 tggctaatgg gtgaccaatt tgattcagtt atgaattact tgatgtcaga agccatgaaa
    30241 aaattctttt gtacagatga gataaacgcc gaagaattta agtatatgat aaatgatgta
    30301 atggtaagtt atccaataca agttagtgaa gttattttta atttacttgg aagtcacgat
    30361 actacaagaa tattgactta tgctaatgga aatattgata gatttaaact tgcatatatg
    30421 tttatgtttg tacaaacagg atgtccttgt atatactatg gtgatgaaat cggaatggaa
    30481 ggagaattaa gttcaatatc tgaaggtcaa agaaaatgta tggaatggaa tgaagaaaaa
    30541 tggaataagg atatatttga ttttatgaag aagattatta gacttcgtaa agaaaataaa
    30601 gaacttaggt ctatatcaaa tgaatgggtg ttagcagata aggaaaatgg aacgattata
    30661 ttgaaaaaag aatctatttc tataataata aataattcat ctaaaaatat aattttgacg
    30721 ttaccagatt atttagcaaa taaaaaagta aaagatttat atgaagaaga aatagttgat
    30781 ttaaaagaag aactaatgtt agagaaatac aagttcatta ttttaaaata atacaaaaag
    30841 tatttatttt agatttcatg ttaaattatt atacagttta aacaagtctt tataaaacat
    30901 aaaaaaatat ggtttacaag tgagtgaatt gaaagtagat tttaaattaa agactgagtt
    30961 agagtagata attttataaa taatatctta aatacaagat agaaaataaa ttgattatta
    31021 gtctaaaaat ttcttgtaga aagaggaaat aagaatgatt gaagcattta tatttgattt
    31081 agatggtgta attacagata ctgcatatta tcactatatg gcttggagaa aactagccca
    31141 taaagttggg atagatatag acacaaaatt taatgaatct ttaaaaggca taagtagaat
    31201 ggagtcattg gacaggatat tagaatttgg aaataagaaa tattcatttt cagaagaaga
    31261 aaaagtgaga atggctgaag aaaaaaataa ttactatgta tcattgatag atgagataac
    31321 ttcaaatgat attttgccag gcatagaaag cttgttaatt gatgtaaaat ctaataatat
    31381 aaagataggt ctatcttctg caagtaagaa tgcaataaat gtattaaatc atttgggtat
    31441 aagtgacaaa tttgatttta tagctgatgc aggaaaatgt aaaaacaata aaccacatcc
    31501 agagatattt cttatgtcag cgaaagggct taatgtaaat ccacaaaatt gtatagggat
    31561 agaggatgca agtgcaggta tagacgctat aaactcagct aatatgtttt ctgttggtgt
    31621 tggaaattat gaaaacttaa aaaaagcaaa tttagttgta gattcaacaa atcaattaaa
    31681 gtttgaatat atacaagaaa agtataatga gtatatagtt aggagaatta tatgaaatgt
    31741 ttatttagta atgtagatga gtggaagatt atacaagata agattgaaat caaagaaaat
    31801 agattagcag agtccataat gagtataggc aatggatata tgggtatgag aggaaactat
    31861 gaggaaaatt atagtggaga tacacacaag gggtcttata tagctggagt atggtttcca
    31921 gataaaactc gtgttggttg gtggaaaaat gggtatccag aatactttgg taaaattcct
    31981 aattcagtca actatatagg tgtaagaatt ttcatagatg atgtagaatt agatttagca
    32041 aaatgtaaag tagaagattt ttatagagaa ttagatatga aaaatggtat tttaaatcgt
    32101 aggtttattg taaatataaa tgataaaaaa tttgaagtta gggttactag gtttttaagt
    32161 atatctgtta aggaacttgc agtaattaaa tatagtataa aatcattaaa ttctaatact
    32221 aaaataaaat ttgtaccata tttagattca aatataaaaa atgaagattc aaactatgag
    32281 gaaaagtttt ggaatggaat ttcttcaagt tctttagaat ataaaggtag tattctttct
    32341 cgaacaaagg agaatgcatt taatacacca gtattcactg tgggttcaat gatgtatatt
    32401 aagacaaatg gtgatgtaga agctgtatct catgagagtg attataatta ctgtgaaaat
    32461 tcgataacaa tggatgtttt aaaaaataag gttgcaagta tagaaaaata tgtatctata
    32521 acttcaacta gagattataa ggaaagtgag ctattaagaa aatgtgaaga cattttaaat
    32581 atagaactat ctaaaagtta tgatgatata ttaaatgaac atacaaagtt atggaataaa
    32641 agatgggaaa gtgcagatgt aaaaataaat ggagataaaa gtagccaaca aggtataaga
    32701 tataatttat tccaactatt ttcaacatat tatggagaag attcgcgatt aaatataggt
    32761 ccaaaaggat ttactggtga aaagtatgga ggagctactt attgggatac agaagcattt
    32821 tgtgttccag tatatctagg tgtagcagat aaggaggtaa ctagaaatct tttagaatat
    32881 aggtacaatc agttagaaca ggcaaaggat aatgcaaaaa aactagggct taaaggtgct
    32941 ttatatccaa tggtaacatt tgatggagta gaatgtcata atgaatggga gataacattt
    33001 gaggaaatcc accgaaatgg aagtatagta tatgcaatat ataactatac aaattataca
    33061 ggtgactata aatatataaa agaaaaagga atagatgtaa taatagaaat agctagattt
    33121 tgggcaagta gagttcattt gtctacaaaa aaagatttgt atatgataca tggagtaaca
    33181 ggtccaaacg agtatgaaaa caatatcaat aataattggt atactaattg tatagctaaa
    33241 tggtgtttag attatgctgt agaaaatatc ttacgattag agaaagagtg taatgaatgt
    33301 attgacagaa ataatgtgac tagggaagaa gttgagtttt ggaaaataat atcaaataaa
    33361 atgtatctgc cgtatgatga ggaactacaa ataataattc aaaatgataa ttttttagat
    33421 aaagaatttg tagaagtaaa ggatttacca aaagaaaatt ttcctcttaa tcaaaattgg
    33481 tcttgggata agattcttag gtcgtgtttt ataaaacaag cagatgtatt acagggaatt
    33541 tactattttg gaaatagatt tactaaagaa gaaaaaaaga gaaattttga cttctatgaa
    33601 aaatatactg tccatgaatc ttctttatct tctagtattt attctattat tgcctcagaa
    33661 atagataacc tagaaaaggc ttatgaatta tactcaagaa cagctaggct tgatttagat
    33721 aattacaata atgatacaaa tgatggactg cacataactt caatgtctgg ttcatggctt
    33781 tccattgtac atggatttgc aggcatgaga acatggaatg aaactctatc ttttgaccct
    33841 aagttgccaa aagagtggaa aaattattct ttcaatataa attatagaga taatattatt
    33901 aatgtagatg tatgtagtga tttaattaaa atagaaaatt taaaaggtaa accaataaaa
    33961 attattgtat atgggaaaaa atatatatta gaaaaatata taaaaattga taagtagatt
    34021 taataatatt tttattatat aaatagttaa aataagttta tttaattatt tatctatttt
    34081 aactattttg tgtgatagaa aactatatat tataacaata gtagtgcctt taattaaata
    34141 tatttcataa atcttcataa aatcttcaaa atttcgtaaa gaatatgtca caaaagtaag
    34201 gtatattata ttcagcagat agtataaggg aggacaatat ttatgaagaa taaaaaattc
    34261 attgttataa tactgataat atcaatttta ataggtgtat tagtgaagga atattcatct
    34321 agagagataa aaaaggatga tataaatgtc agtaagtata taaaatatgc tgatttagca
    34381 agtaaaaata atgcacaagt taactggaag tatgtagctt ccattgttgc tgtgttaaat
    34441 aaaaataact taaaaaacgt taaggattca cagatacaag aagtatcaga tttatttgtt
    34501 aagaattttt ctaaaaataa taaaataaat aagttaagtg atattttgga tgagttagaa
    34561 tttagtaata gacaaaaaag attggttgat aattatatag acaatcttaa ggattatggt
    34621 ataaaaccag aaagattgaa gtctgataca aaatatatga agtttattgc tgaaattaaa
    34681 acagaagcaa tacaaaatta taaggattat aaaatacttc catctataac tattgcacaa
    34741 gctataatag aatctagctg gggcaagtca actttggcaa aacaatataa caatctattt
    34801 ggtataaagg ctgacgctta ttggaaaggt aagtcagtga ctttagaaac gaaagaacat
    34861 ttagatacaa ttatagatga taaatttaga atatatgatg ataaaaatga atctataaaa
    34921 gaccatgcaa aatttttagc cacaaataaa aggtataaaa acaatggtgt atttgatgca
    34981 aaaacgtata tatatcaagc taaagcatta gaaaaggcag gttatagtac tgcgaaggat
    35041 gaaaatggca atagtatata tgcagctcgt ctaatagaat taattcaaca gtataatctt
    35101 caattaatag acagcgaaat tcaaagtgaa gtgtaacttt tatgtaacat aggagtgata
    35161 tatttatcga ggaggtggtt tttatgaaaa aaatattctc gatatttata agttgtatgg
    35221 ttgttgtaac tactattact ggatgtagta gtggtgaggt gataaaaaat acatcaccta
    35281 tcaatagtgt taaaaatttg gattttagtt ttgaggtgaa acctgaaata tttgaggtat
    35341 cagttgaatc tggtggttca aaagaaaaga tatctgaacc ctcaaaagaa aggaaagtat
    35401 caaattttaa aaagaataag acagaggcat cgtggacgta tcctgatgaa aatatagaca
    35461 taaatataaa aaaagaggac agctatttag atgtaaatat taaatctaat ttagaaaaag
    35521 aaactagttt taattggccc aaagttgaag gggaaagtta tatactacca ctttatgagg
    35581 gtaagtttat accaagtaat gataagtatt ggaaggagta tctaaatgag tcaacttata
    35641 atgttataga atctttttca atgcaattct ttgcagtaaa caaggcaaag tattctgtga
    35701 tttatattat cgaaaatgaa tttaacaatg taattgaatt tagttctaaa gacaagatta
    35761 attttacatt taaacatgaa tatccaagta tcaataaaaa taaggagtat gggtttaaaa
    35821 tatatttgac taataagaat attacagatg tagcaaaaac ttataaaaat tatatagttg
    35881 ataaaggaga atttaaaaca ttaaaagaaa aatctaagga aaataaaaat attgaaaaac
    35941 tttatggagc accacatatt tattttggag ataagtctat catcacaata aatgatattg
    36001 aatggaataa attaaaagaa aatttatcag atgatttgac taattggatg aaagagcttt
    36061 taagtatgaa gtctggcaat agtgaattta taaaagtaat taatcaaata aaaactcaag
    36121 attatataga taaatatcaa aaaaatcaaa tagtacaagc atttaatgaa gttatgcaga
    36181 tgaatacttt ttataatgaa aaagtttttg aaagcaaaga tagagaaata aaaaaagtat
    36241 tagataaagg tatatctaaa ttaagtaggg tagaacttat agagtttaat aagaaattat
    36301 tgaaatcaaa attggaagag agcgtgaatg atgttgctac atgggcaaaa tataatacaa
    36361 ctgatgtaat taatgatatt aataagtctg gtattaaaaa tgcgtggata ggatttgatg
    36421 atatggagga aggttatata tccttagaga tggttaaaag agctaatgag ttaggttatc
    36481 tcgtagggcc atatgattca taccactcta tacacaaacc aggggaagaa aagtggagta
    36541 cagcatcatt taaagataaa tctctatatg aaaatgctac catagaaaat aaaaaaggtg
    36601 aaaaagaaac tggatttcaa ggagaaggaa gaaaactaaa tcctacattg tctttaccaa
    36661 gtgtaaaaga gagagtacaa agtatattgg atgaaggata tgaatttaat tcttggttta
    36721 tagattgtga tgctacagga gaaatctatg atgattattc tcaaaatcat ataacaacac
    36781 aaacacaaga tttaaatgct agacttgaaa gaatgtcata tataagagac catgcaaata
    36841 tggtcatagg ttcagaaggt ggaaatgatt tttcaagtag tactatagca tttgcacatg
    36901 gtattgagac accagcattt gcttgggtag ataaagatat gagtaagaat aaaggcagtg
    36961 aatattatgt tggtaaatac tattctccaa caggaggagt accagaaata ttttcaaagc
    37021 agatacctgt aaaagaaagg tacaaaaaaa tatttataga cccaatttac tctctacctt
    37081 tatttagatt agtttataat gattctgtga tatcttccca tcagtggtta tggggaactt
    37141 tgaagattaa ggatgaagtt ggaagtagaa tgatgaaaga agtattatat aatacaccac
    37201 ctatgtatta tatagataga actgaatggg aaaaacataa agatgaaata atctcaaaca
    37261 ataaagtatg gtcagcgttt aataagaaag ctattaaaaa agaaatgaca gactttaaat
    37321 ttatttctga ggatagacta gttcaaatga ctgaatatgg agaagattta aaggtattag
    37381 ttaatttttc tcaaaaagac attaagtaca atgatgaagt cataaaagca aattctttgg
    37441 taatatatga tgctgatagt aaagtcatat ataaaccgga ataatagatt taatgaaaat
    37501 aaagattgtt taaatttcaa gtaaaaaata atataatatt catttagttt gtattaaagt
    37561 agtgactata ttaatctgga taattagtat agtcactatt atttatattc tttcctaaaa
    37621 gtaagtagta actgaatcgt gaataatcaa aaatggtaat ttgaaatagt ttttatgaat
    37681 agtattaata tatagatata gggagattga tgtgattatg tatgaaaata ataaggtaat
    37741 atataatttt gaaagatgtg aaaagctaga aaatgctctt tatttatctc aatttaatac
    37801 atataaaaac tttaagttaa cttctaaaaa aactgtaata aactcattag atacatctac
    37861 ttataatatg aatattcata gcataagtct cgttgatact atggaatgta tatcgtcaga
    37921 agatgaacaa atgacaggaa agaagttgat tttagttggc gatatagata ctgatgtaac
    37981 attagattat gcaggcaata aaagaaatag aaattctagt aaaaaaaata catttaaatt
    38041 aaaaataccc tttagtacat ttatacaaat gcctagaaag atagaaaata aagataaaat
    38101 taatttaaag tatcttatac aagatattac ttcatctatt ttagatgata atttatttat
    38161 tagtgttact gcaattataa gttatgaaaa tagttccaag atagagtaat ctttaaatta
    38221 tagaaaggtg gatgcaatga gaataacgaa aactactttt aatgatgtat tttcaaatga
    38281 tgcaaatgga agtattataa aagtagaaaa atatgttgat aaaaaatgtg catctgtatt
    38341 tgagattttg acctacacta ttattgttac aaatacaagt aggtacaaaa ctggaaatat
    38401 atttttcaaa gattatattt ctaaatatat agagtttata aataatactg taaaagttaa
    38461 tggcattata aaacgtggat tagacccaca gcaaggtttt tacataggga gaatagatgc
    38521 aagttgtaaa aaaataatat cttttaagag tgtagtttta ccaaattctg cacataggat
    38581 tataaagaat agtgctaata tatactatta ttataagtgt aatctagata aattcccaac
    38641 aagaatatca atagaaagta atagagttta tactaatgta aataaaattg tattcaaaca
    38701 attgaatata agtaatactt taaaagctcc taaaaatcta agagatatat taaaagtaaa
    38761 tgtaaatagt aaaatatttg atgttaaacc tatgaaaaat cttataaaca aaggtagtaa
    38821 tttgaaatta tgtaactcga tagtttttgg gtgtatagaa gttgaaatag actatagttg
    38881 taaaaatagg agtaatttta aaacagtaaa taagtttaat gatattaaaa aagataagta
    38941 ttataaaaat gatatacaaa ataacaatga aaatataaac gattgtaaaa agcaaataag
    39001 ttttggtgat aataaggtaa aaaaaataac aaaaactttt ggattttctt gtttcatttg
    39061 ttctccagtt ggaattattt atgaagatat gaaaaatata aatataaaaa ttgaacatac
    39121 atcaataaat gaattaaatc cagaagaatt atttgtaaat acatcacttt tattgtatta
    39181 ttaagtattt taaagctaaa acttaaactt attaaaatag catttggtta aaggaaaata
    39241 gatattgata tatttataat atatataaat gattaattaa acaattataa ataataagta
    39301 tagtataata tttaaaaaat atagacttat gataaaataa gacaaatatg ttaaaaaaat
    39361 gataatcacg gagaactttt accttcttca attaatatat tattattagt aataacttta
    39421 aaattatatt actattatat aaaaattggc ttaaaagaag gtgaaaaaag taaatgaaaa
    39481 tatgcataac agtaggtcat agtatactaa aaggtggtaa aagtacaggt gtaaatggta
    39541 tagttgatga atacaattat aataaaaaat tagctcctat gttagctgag atgcttataa
    39601 gtcaaggtaa tacagtagat gtaataattt gtccagaaag gcactttatg tcagaaagag
    39661 aagaattttt ctatagagtt ccaaaagtaa acagtggtaa atacgattta ttagtagagc
    39721 tacatttaaa taaagctgat ggaacacaat gtggtacaga agtgctttac tatggcactg
    39781 aaggattaga atatgctaaa agagtatcta atagacttgg agaattattt gaaaatagag
    39841 gagctaaaaa aagagaaaat ttatatatat tgagaaatac aaatccagtt gcaatacaga
    39901 ttgaaagttt tttctgtgat aatgtgaatg attgtaacaa agcaaatgaa tcaggttatg
    39961 attatatagc acgattgatt acagaaggta tattgaataa agatataaat atgtgagatt
    40021 atggtgattt aggtattgat taataccttt taatattaga tataaataaa aatacaatgt
    40081 attagtataa tttaaacttt caaaatatag attagtttga ttattgacaa gagatacctc
    40141 ctaaatattg atttatcagt atatttaagg aggtatttaa atataaaaat ttaattgatt
    40201 tgctactaaa ctataggttt atagagtata tatttttatc ttcagtctaa taaataatat
    40261 aaaaatagta gaaccttgta ttataataat ataatgtaga aaaatatata gataagataa
    40321 atataataag gtggtaatat atgaaatata catttgaaaa atttaagtta aatgaaaaga
    40381 tacttaagtc attgaagagt ttaggatata atataccttc tagagtacaa agagaagtta
    40441 ttccaaaatt attaaaaggt caaaacttag tagttaggtc aaaaacagga agtggaaaga
    40501 cagtaagttt tgcaatacct ttatgcgaga atataaatgt agattgcaat aatattcaag
    40561 ctcttatagt ggttccaaca agagaattag ccttgcaagt aaaagatgag atatcagata
    40621 tagggagact aaagaaggtg agatgtagtg ctatatttgg caaacaatct ataaaagacc
    40681 aaatagctga attgaaacaa agggttcata ttgttgtagc tactccaggc agaatacttg
    40741 accatataaa taaaggttct attaagttgg aaaatgtaaa gtatttagta atagatgagg
    40801 cagataaaat gtttaataaa ggttttgttg aacaaatgga aaaaatatta ttaaatttac
    40861 ctaaggagaa aatagtaagt cttttttcag ctacaataga tgaagagata aaatatatat
    40921 gtgaaaaata tatgctagat tacagtgtta taaatataga agaaaatgag agcgatacta
    40981 atcaaaaaac aagacaaata gatgacaaaa taatcaaggc aaatggaaga gagaagtaca
    41041 tccttttaaa agaattaata tacagcgaaa atccaaagag tgtgataata ttttgtaata
    41101 ccaaagagaa agtatctaaa ttatataata agatgagtaa agagggtttt ttaataagag
    41161 agttacatgc agatttatca caagaaagaa gaatttttgt aattaaggat tttaaaaacc
    41221 aaaaatttaa tatattagtt agtagtgatg tagcgtccag aggaatacat attgatgata
    41281 tttctttagt aataaattat gatgtgccac aagataaaga aaactatata catagaatag
    41341 gtagaactgg gagaaaagga aatagtggaa aggcaattac tatagtaact gaaaaggatg
    41401 aaaaatatat agagaatata gaaacgtata taggatataa agtaaatgaa ttaaaagata
    41461 tagaaaaaag tagaattaca catggcaaaa ttttgtttga agaatattca aaaggaatcc
    41521 taaaaaaagt atcaaagaga aaaaaagttg ataaaaattc ttacaaaagt aaagatataa
    41581 aactaaatat agaaagtgaa gttgttaaat tatatttaaa tgctggtaag aagaagaaaa
    41641 taagagtttt agatatagtt ggtgcattta gtaatataaa aggtataact aatgatgata
    41701 taggtgtaat tgaagttcaa gatttatgtt catatgtaga tatattaaat tataagggag
    41761 atttgatatt aaaaaaatat aaggagatac ctataaagaa aaaaatggtt aaagtgaaaa
    41821 gagatatacg ataatttagt tattactgct ctctctgatg atgaaatcat atatttaagt
    41881 aagagtatca atatttatga attattctgt tatcgaaatg aagtttcaaa aaacaataga
    41941 agttgttaag gaaaggaatg ttgactttat ctacattcta agctatacta tttttaaatg
    42001 tttatgacaa tagtcatttt aaatataagt aataaatata tacctatagg gatattaaag
    42061 gaggtaatat atggcatatt ttaactataa cgacaaacag tgctactata atgaaattgg
    42121 ggatggtaca ccattacttt ttttacatgg aaatacagcc tcttccaaaa tgtttaatga
    42181 tataatcgat ttttataaag atgaatataa agtaatatta attgattttg taggtcatgg
    42241 aaaatctcaa atggtcgata aattttctgc tgacttatgg tttgatgagg ctatgcaagt
    42301 gatatgtttt ttagaagcaa tgaactataa aaaagtaaac ataattggta gtagtggagg
    42361 agctcttgtt gcattaaatg ttgcacttga gagacctgat ttagtgaata aggtaattgc
    42421 agatagtttt gaaggagaag ttcctttaga gtcatttgta caaaatgtta aaatagagcg
    42481 tgaggcatca aagcaagatg atggtgcaaa agctttttat atttataatc aaggagaaaa
    42541 ctgggaaaaa gttgtagata atgatacaga agctattttt gaacattata aaactatagg
    42601 aaaatttttt cataagcctc tagaaactat gcaaccagag gtgcttttaa caggaagtag
    42661 agaagatgag tttgtatctc taatatctag tgattttttt gaaaatactt tttcattact
    42721 tcttgaaaag attaaaaatg gtaaaatgta tttgtttgat aaaggtggtc atcctgcaat
    42781 tttatcgaat ggattagatt tttcaaatgt agcaaagaaa tttttagagg aataatttaa
    42841 ccaaaattta caataatgaa aactgtaaaa tggattgcaa aacttacaaa agtgagtgta
    42901 catatacttc attattatga tgaaatagga ttgttaaaac aaaatattct aatagtcaag
    42961 ttattacatt tgtatatgca atatgtatag aaagagatat cattagattg taaagttggg
    43021 attaaataac aatatgaaat tttatttatt cagatattgt agcttaacta tataaatgtt
    43081 agaataaatt tatatagtta agctgtagga ttaaataatt tagttaaata agtctattat
    43141 ctcttcatca gatagacttt ttaatacacc ttcattagaa agttctccat ttataaattg
    43201 atttataagc tcttttttac tttcttgtaa ttttattatt ttttcttcta tagtcccttt
    43261 agcaatcaat tttataactt gtactgaatt tttttgacca aatctatgag ctctatcact
    43321 agcttgattt tctactgatg gattccacca tgggtcaaag tgaattacca tgtcagcaga
    43381 tgtaagattt aaaccagttc cgcctgcttt taaagatatt aaaaaaactt ttttatccat
    43441 actattattg aactcatcta caagttcaag tctttctttg gcattagttt taccatctat
    43501 ataatggtat ttaattttat acttatcaag ttccttactt atgttcttaa gcacagaagt
    43561 aaattgtgaa aacaataata ttttgtggtt ttcgtttata ctatccctaa gtatttctaa
    43621 acatgtttca atttttgaac tttttttatt gtaatctttt actactatac ttgggtctaa
    43681 acaaagttgt cttagtttag ttaaataaga aaatataact attttatctt tctttagatt
    43741 tttatctttc attttatctt gtatatcttt tgaatataca ctatatatct ttttctgctc
    43801 tttattcaat tcaacaaaaa agtttttttc aatcttatct ggaagttctt tcataacttg
    43861 ttttttactt cttctaagaa taaaaggttt tattaatttt ttcaggtttt taacattatc
    43921 ctctttattt ataaacaatt cctgaaactt tgctttacta tatagatagc caggcattat
    43981 aaaatcaaat atagaccata attctagtag attattttcc ataggtgtac cagtgagtgc
    44041 aaatttattt tctgcattta tactttttac agactcagtt actaaagcta ctggattttt
    44101 tatattttga gcttcatcta atatacaata atcaaacttt atttcactat atttttctaa
    44161 atcatttcta agagtaccat atgttgtaag tattacatca aaattttcta attccataaa
    44221 acatttttct ctatctcttt tattcccatg tatcaataaa acttttatat ctggagcaaa
    44281 cttttcaaat tcatttttcc aattataaat gagtgatgtc ggtgtaacaa taagactttt
    44341 tttattagat aatgataata aaaatgcaat agtctgtatt gttttaccaa gacccatttc
    44401 atcagctaat ataccaccaa atttataata atctaaaact ttaaaccaat tgaggccatt
    44461 tatttgataa tcacgaaggt ttgcatttaa atttgcggga atttctaaat ttatgctatc
    44521 aaaatttcta aatttttcac atatactgtc tagttctttt ttaccatcta taaactttaa
    44581 atttttacta cgtattacat catttatata tagagcttta tttttataaa ttttattatt
    44641 ttttgattta tccattatat ctagattttc aactaattca aaaaaatctt ttgtttctct
    44701 ttctgataaa tctataaagt ttccatcttt aagtttataa aaagtacgtt tttcttgaaa
    44761 agctttcaaa atatccttgt actcttttgg atttatatca gatatattaa aattaaattc
    44821 taggtaattc tggttagtct gattgattga agcttgaatt gatgaagcgt tatatatttt
    44881 tttcaattta aacttctcag aataatatat atctccaaat tcctttagag attctaattg
    44941 taaatctaaa aatgtaaata ggtcatagtc agttccttta aacacataat gattattttc
    45001 ctttgtaaat tgtgaagaag taagtttatt ttcaatagta gtttcctttt gtatgttggg
    45061 gagcacaaat tttttatcct catcatcata tatatacttt acatcacaac atatgttgcc
    45121 atcaatcata tcaaagtaga actcagattt aaaatctttt gttatattat tttttatgtt
    45181 atcatctaaa tgaacttctt gagatataga ttttaatcta ggaactagca atcctaaaac
    45241 atccttagaa tcctctttat caaattttaa ctctttagtc tttgataata tttgatatat
    45301 ttttgaataa tcatgagctt ttttatgtga taataaatag atattgccat catataaaag
    45361 tacatcattt tttttagtaa gtggaacagg tagtgaatct ttagaatata agactatttt
    45421 atcttctata tttttaaaat caaaccttac aggtagagta tcatttaata tctttggatg
    45481 atattcctct ttagaaaaaa taagggtaaa atccttgtac ttaatagcat ttaaaaattg
    45541 ttttaaagag cttgcattta tctccataaa tttttttgaa tgtgatgaag aaaagttgta
    45601 tgaaagattt gtcccatatt cttctataat atctactaac ttctcatctt catcagcaaa
    45661 ataatgaatg ttggggttgt aagtaaattt cttcccaaaa tctaattcat atccattaag
    45721 ttttgaatat gcaaattcag taatgttttt taaaatgtac attttatcaa ttcctatttt
    45781 aaattcagca attgctttat ttgaatccac atttatcaat acatctaaat taaccctttc
    45841 tcttttagta ttgtctaaca aagaaagtaa ttgcttgctt aaatctaagc ttgttttaga
    45901 atttgtatta gaaagcttat ccttatctgc acctaatata tctattagaa taggaggaac
    45961 atctctttta ttttttattt gttttaagct ttttatcaca atagcaacta tatgcttaca
    46021 tataaaaata cttttgccct ttgattgaca gtcagcgcaa ctacaatcat tttcaattat
    46081 cttaaagtgc tttatatcta tagttattga attaaaataa aagctataat tatcttcaga
    46141 attgactcca ccacgaaatg tcaacaggtt attttgtagg tcatcaatat ctatgtctat
    46201 ataatcaact aattgattag tataatattt tacacctctt gaccatcttg atggttctgt
    46261 atttcttctt attagtttat atatcatatc tattttcata ttattcacct tacctcactg
    46321 tatatattat aatctaaatg cattcaattt acactctaaa tttaagacta aaattaaggc
    46381 agatatgaat agcttttatc tattacaata tatgtgtaaa taacaattta ctattagatt
    46441 tttattgaat
//
LOCUS       DAEQJM010000027        44082 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.027, whole genome shotgun sequence.
ACCESSION   DAEQJM010000027 DAEQJM010000000
VERSION     DAEQJM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44082
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.027"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(54..215)
                     /locus_tag="KRQ43_001840"
     CDS             complement(54..215)
                     /locus_tag="KRQ43_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742197.1"
                     /translation="MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFD
                     FKIKFHKFK"
     gene            complement(556..996)
                     /locus_tag="KRQ43_001841"
     CDS             complement(556..996)
                     /locus_tag="KRQ43_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH2742198.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYVASNRFLDKEGKPVEWELKVLSSE
                     EDEALRRKCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN"
     gene            complement(1068..1895)
                     /locus_tag="KRQ43_001842"
     CDS             complement(1068..1895)
                     /locus_tag="KRQ43_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742199.1"
                     /translation="MEFESGIKLGKLTLIKYLGRNKHSKKVWLCQCECGNKVERVENN
                     LKQSIKNEKPPHCGCSPNWKGQNKRFKDITGKTFGKLTVLKMSGKDKYSHNLWLCQCE
                     CGNRTITSTSALEQGKAQSCGCIRKEILLERSTTHNKSNDSLYRVYHRMIKRCTNKSN
                     KDYNYYGGRGIEVCNEWLEDFINFYNWSIENGYRKGLTIDRINVNGNYEPSNCRWVTW
                     EVQRNNKRNSIRVNYKGEMITLKQCAENLNVKYLFLYNQLVTKKIPLEEVIKNIGME"
     gene            complement(1954..2424)
                     /locus_tag="KRQ43_001843"
     CDS             complement(1954..2424)
                     /locus_tag="KRQ43_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH2742200.1"
                     /translation="MAQTINAKDTVSAKKAECFITIEGKRYNFMQAIDLEAKMEKNKS
                     EVPILGRTTKGNKTTGSTNTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SAVGRQTVVLKDCNMDSGIITKFDADGEYLDEDMDFTFEDWELVESFALLNGML"
     gene            complement(2441..3751)
                     /locus_tag="KRQ43_001844"
     CDS             complement(2441..3751)
                     /locus_tag="KRQ43_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBH2742201.1"
                     /translation="MALGGGTFVTQNKILPGAYINFISAKRATSSLSDRGIVAMPLEL
                     DWGIDEEAFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVILLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSIENKIKDKDLVESSLIYWATGAIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAIKVINAMSKLYMTVSVN"
     gene            complement(3752..3928)
                     /locus_tag="KRQ43_001845"
     CDS             complement(3752..3928)
                     /locus_tag="KRQ43_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742202.1"
                     /translation="MSKALSKEDNYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEDRINKFMKGVS"
     gene            complement(3921..4358)
                     /locus_tag="KRQ43_001846"
     CDS             complement(3921..4358)
                     /locus_tag="KRQ43_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742203.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEDKNFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKNNDTNKMDTVELFGGLKRGDNFE"
     gene            complement(4707..5513)
                     /locus_tag="KRQ43_001847"
     CDS             complement(4707..5513)
                     /locus_tag="KRQ43_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742204.1"
                     /translation="MAKFLDITGKKFGRLRVIKFSKEIKSGKRNRKYWLCKCDCGNFK
                     EIRTDSLTSGLVQSCGCLKKEQDKLNLTDKYQFKKKYKVQNKRLYSIWKGIISRCTDK
                     NNKRYNRYGERNIIVCDEWFCYDNFANWALSNGYSEKLTIDRINNEGNYESSNCRWVD
                     IKTQCRNRSTNILVKHEEKEITLIELSEKTGISYSCLRSRYSKGLVGNKLIEKVKIIE
                     ESRAKLSIEDVKEIRKKYSDGYTIKQLSEIYPVTYSSISNIVHRRTWKNI"
     gene            complement(5623..5913)
                     /locus_tag="KRQ43_001848"
     CDS             complement(5623..5913)
                     /locus_tag="KRQ43_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBH2742205.1"
                     /translation="MARWGSVDFREFKRVCKKMEKFTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLREGWSGVAYARSLPVYKQGNNYIIEVVNPTEYALTQWGI"
     gene            complement(5913..6260)
                     /locus_tag="KRQ43_001849"
     CDS             complement(5913..6260)
                     /locus_tag="KRQ43_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742206.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKLAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            complement(6254..6655)
                     /locus_tag="KRQ43_001850"
     CDS             complement(6254..6655)
                     /locus_tag="KRQ43_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742207.1"
                     /translation="MENNIIDEIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNKILTFRCLRW"
     gene            complement(6665..6898)
                     /locus_tag="KRQ43_001851"
     CDS             complement(6665..6898)
                     /locus_tag="KRQ43_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742208.1"
                     /translation="MPQVKKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLSV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            complement(6917..7807)
                     /locus_tag="KRQ43_001852"
     CDS             complement(6917..7807)
                     /locus_tag="KRQ43_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBH2742209.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATENNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTANVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEA"
     gene            complement(7819..8382)
                     /locus_tag="KRQ43_001853"
     CDS             complement(7819..8382)
                     /locus_tag="KRQ43_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBH2742210.1"
                     /translation="MDWLKELLEGIKVEDNKIDVASLQKSIEKKIKETTVTQEDYVNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDMEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            complement(8450..8698)
                     /locus_tag="KRQ43_001854"
     CDS             complement(8450..8698)
                     /locus_tag="KRQ43_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742211.1"
                     /translation="MDNKFKNLQHLIDSIDLGLDIEFDLYNKPYNISIGDDDTRFITL
                     CPNGDTKYYKNGKDMVDNYNIDGKLLKDLWKDIQIVNM"
     gene            complement(8700..10235)
                     /locus_tag="KRQ43_001855"
     CDS             complement(8700..10235)
                     /locus_tag="KRQ43_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBH2742212.1"
                     /translation="MKHKDYWRKRFEQLEEVQNNKSVKYYLELEKKYKLAMNSIEKDI
                     LSWYNRFAENEGISLLEAKKLLNTRELEEFKWNVEEYIKYGKENAINQKWMKELENAS
                     ARLHITRLEALKLQIQQHVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKIISKPWATDGLNFSERIWGKHRPTLINELHTKLTQSIIRGENPKNLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFSDLDVEKYEIIATLDLRTSNICRE
                     LDGKIFDMKDYQVGITAPPFHCRCRTTTAPWFEDEEGYRAARGEDGKTYYVPSSMKYN
                     EWYEKHIEGRLGKEKADTLRKMQLNESKDRKQFEEYKKVLGNEIPSKFDEYQHMKYND
                     TIRYEEAKKLYKDVNWQVKNQRNLTSGSVHSVPFESKPNSVFDNYKDGKLIQRRYYGN
                     TGKPRLDLDLTDHRNPKQHKIVPHKHDWLADENNHDKVKREKDMELTKAHKIANKDIL
                     NGE"
     gene            complement(10225..11667)
                     /locus_tag="KRQ43_001856"
     CDS             complement(10225..11667)
                     /locus_tag="KRQ43_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH2742213.1"
                     /translation="MLNIYISETDLIKVQLKKESTFNLVKVIEHYILKHRPEKYKQGE
                     EYYYGNTDVNNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVDQKVGYSVGNPIVFNA
                     DDDNLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDSKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFIERGNSFIQEFLYDEYG
                     KMTDIQEGHFRINNKEQGWGKVPFIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNL
                     DEMQEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISGSKSYDYKSVQITFNHSMIINESEKIDMASKSIGIISDETIVSNHPWVEDVNDE
                     LERLKKQEETQKEYDDLIPTNNQEGVIDET"
     gene            complement(11673..12926)
                     /locus_tag="KRQ43_001857"
     CDS             complement(11673..12926)
                     /locus_tag="KRQ43_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBH2742214.1"
                     /translation="MVIEMIVRINFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDY
                     ILKLGDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIK
                     SKVTGNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGI
                     LTNPNLYYQMTFTFNPVSATHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQM
                     RKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANAIL
                     RIGFKDGELYICNEIYVHEMDTSEIIKIANSRGLEKTLFMYCDSAEPDRIKMWKSAGY
                     KAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEF
                     MDDAMAALRYSIDNKLKNNGISFLK"
     gene            complement(12904..13596)
                     /locus_tag="KRQ43_001858"
     CDS             complement(12904..13596)
                     /locus_tag="KRQ43_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2742215.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISAKYDISLNTLKSWIKRYNWSSE
                     KKKGAPINKRGAPFSNKNSVGYGAPKENKNAEKFGFFSKYLPEETRELIQEISIKDKF
                     DILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHEITENSEKIEYEFQFAWDRQAS
                     FLNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVANLNKDDIGDDEL
                     KISVDYGDRNDS"
     gene            complement(13666..14175)
                     /locus_tag="KRQ43_001859"
     CDS             complement(13666..14175)
                     /locus_tag="KRQ43_001859"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742216.1"
                     /translation="MYKKVLNILLNYYKAINSKEVVELVLTPVLICIISYMFFNSSIN
                     KEVVISLNKDVLTLSGLLVAFGVCIITLLFTTYNKSISEAKDIKTERKVNGFNISYFQ
                     FIQLKAYYTVIMEILVVVICFINTIMLTRYYSNIIFYVLIFFTVHIILSLTTLIISMF
                     HLSWKDRGD"
     gene            complement(14196..15170)
                     /locus_tag="KRQ43_001860"
     CDS             complement(14196..15170)
                     /locus_tag="KRQ43_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742217.1"
                     /translation="MSNFKKRYIDVYRIDIINKINGSVYSDEEILKEVIKTFFKDKEY
                     CKENKNGINITKDKKFWITEVKCSEDDLIIKVKLEYTKYNQNTNIINAHTKEVEGNKK
                     MDQGDSNKQHLFIKFMKENNIAVVLFERVFVGVPMIELSKNLHLYYEDMIENNKFDNN
                     MSKTSINITQIASKDFIEQILDLDGVSKITLNVDREKFGTDEDNLFSNLNNSRRHNDL
                     IYKPTFRTRYLPSEVKRCCEKYIKGEEFRNKKINRIIIEGEKNKRKLKLDTEGIKLCR
                     EIEVSLDIDNHIDSEDIFEKMNNLIDDLIENNSVFFNLMYQEVAMSEA"
     gene            complement(15365..15914)
                     /locus_tag="KRQ43_001861"
                     /pseudo
     CDS             complement(15365..15914)
                     /locus_tag="KRQ43_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994390.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
     gene            complement(16197..16676)
                     /locus_tag="KRQ43_001862"
     CDS             complement(16197..16676)
                     /locus_tag="KRQ43_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 region 4 domain-containing protein"
                     /protein_id="HBH2742218.1"
                     /translation="MDKESIKEIVRELRKEEREDRKKGVLYNTRLLMKHYNDFKRHID
                     SAVSEAKDVDYLEDDLGKLDNEELYILSIKKSKARTIIMIAHIDSAMKTLKLRQERLH
                     SYEKYRALELYYCDEKTYEEIAEILNCGVVTSRRWINEMVKELGVYLFGIDGLKLTV"
     gene            complement(16669..16806)
                     /locus_tag="KRQ43_001863"
     CDS             complement(16669..16806)
                     /locus_tag="KRQ43_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742219.1"
                     /translation="MELISPGKIVRCAWCGRRFYKLDKSKVEYCSRSCSKRARRSDLS
                     G"
     gene            complement(16830..18200)
                     /locus_tag="KRQ43_001864"
     CDS             complement(16830..18200)
                     /locus_tag="KRQ43_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH2742220.1"
                     /translation="MEFKPHPYQEYTIRKTIDNNNIGLLLDMGLGKTVCTLTAISELM
                     YDYFDISKVLVIAPLRVARDTWSSEVKKWEHLKHLKVSKVLGSKLDRVRALSTDSDIY
                     IINREMVPWIVDFYKRKWPFDMVVIDELSSFKSNKAQRFKSLKKVLPLTKRVVGLTGT
                     PTPNSLIDLWAQMYLLDRGERLGKTITGYKERYFEPGQKNYQTGAIYNWQPKNGAENA
                     IHNKIKDICISLKAEDYLNMPRKIDNKIEIHLDSKILKYYKELEKEKILELDRDIITA
                     SSAAVAANKLLQLANGAIYDNDKNVKELHREKLEALKEIIDVSNGKPIIVFYNYKHDY
                     NRLMKEFKSLKPRTIENSKDIYDWNNGRIQLLLCHPASTGHGLNLQSGGSIIVWFGLT
                     WSLELYQQANARLYRQGQRETVIIHHLICKGTIDEQVMEAIENKDKGQSALLEAVKAK
                     LKEYRE"
     gene            complement(18149..18475)
                     /locus_tag="KRQ43_001865"
     CDS             complement(18149..18475)
                     /locus_tag="KRQ43_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HBH2742221.1"
                     /translation="MLESKIEKRLKKEIELLGGKAMKFISPGEAGVPDRIVLLPEGHV
                     IFVELKAPGKKLRKLQQYKMRELRELGFKVKCVSTLKEIDDFIKEVKGWNLNHIHTKN
                     TQLEKL"
     gene            complement(18757..21174)
                     /locus_tag="KRQ43_001866"
     CDS             complement(18757..21174)
                     /locus_tag="KRQ43_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742222.1"
                     /translation="MDIKASEIEHINVRHDGQLMLAIGKNKLETHWKNKSILWSELVN
                     RLSKTLRTQETYTEYRKMSKTEKDRVKDVGGFVGGSLKNGRRKAENIANRSIITLDID
                     YANKDIWEDITLLNDYACLMYSTHSHTENNPRYRLVIPLTRPVLPEEYQAISRMIADT
                     IGIDMFDDTTYQPHRLMYFPSTSIDGDYIFKFQDGEFLNPNEILDLYLDWTDVSYWPE
                     SSRERQKFNTQLKKQQDPIEKAGIIGAFCRSYSIKETIENFLNEVYIPGIDETRYTYS
                     EGSTSGGVVIYDDKFSYSHHGTDPASGILCNAFDLVRIHKFGELDEDAKPETPVNRLP
                     SFTRMSEFASSDTKVRKTIGRENLDKAKDDFGDIDFEDDEWLTRLDYDNKGSYKKTTN
                     NILMFIENDPYLKGKIAYNEFSNRAVVLGKLPWRKDDKLNDWNDSDDSGLRHHIETIY
                     NISSPSKVNDALIIAFENNTFHPIKDYLNSLKWDGIKRVDTLLIDYLGAEDNHYTRTI
                     IRKVLVAAVARVFNPGIKFDNMMVLSGPQGMGKSTFIKKLGGDWYSDSLTTVQGKEAY
                     EQLQGVWLLEMGEMMATKKADIEAVKHFLSKSEDIYRVAYGKRTSRFLRQCVVIGTTN
                     DKEFLRDKTGNRRFWPIDTGVKKVNKSIFNGQLDNERNQIWAEAVELCKANEQLYLSD
                     EEKKEAERQQRTHSEENAKSGIIEEYLNKPITENWYDLSISEKREYIHGSDFGDLKEG
                     TILREKTCVMEIWVELFNGEPKQLTPILSREINDILKGLDDWISYNGNLRFGKIYGRQ
                     RAYVRKS"
     gene            complement(21186..23144)
                     /locus_tag="KRQ43_001867"
     CDS             complement(21186..23144)
                     /locus_tag="KRQ43_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HBH2742223.1"
                     /translation="MRTLSIDIETYSDLDIKKVGVYRYVDSANFEILLFAYAFDNEEV
                     KVIDLVNDEELPKEVIEALNDNKVIKSAFNANFERTAISKFLNINLKPNEWSCTMIKA
                     LTLGLPGSLDSVSKALKFNEDKQKMKEGKALIQYFCKPCKATKVNKGRTRNLPIHDME
                     KWNKFKEYCKQDVVVEREIRNKLSKYKTTEREIKLWYLDQRINDTGIKVDTELIENAI
                     ECDKRYTEKLTKEAIKITGLNNPNSPAQLKKWLSDKVGFEITSLTKESIPEILKQVDD
                     ENVVRILELRKLMSKTSIKKYEAMKLAKGNDNRVRGLLQFYGANRTGRWAGRLVQVQN
                     LPQNHIEDLDLARNLLKEGDFDLIELLYDSVPDVLSQLIRTAFIPSEGHRFIVSDFSA
                     IEARVIAWFAGEKWRLDVFNSHGKIYEASASHMFKVPIESIKKGDPLRQKGKISELAL
                     GYGGSIGALTSMGAIKMGLDEEELQPLVTTWRNANPNITKFWWDVDKAAKKAIKDRTI
                     VKLQHGIKFIYNPGVLFIELPSGRRLSYLRPKIEPHTTFSGDKITYEGMEQTSKQWKR
                     IDTYGPKLVENIVQATARDCLREAMFNVTDAGYSIVMHVHDELVIDVDKKGGSLEEVN
                     SIMGKEISWAKGLPLKADGYECDYYKKD"
     gene            complement(23144..23716)
                     /locus_tag="KRQ43_001868"
     CDS             complement(23144..23716)
                     /locus_tag="KRQ43_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HBH2742224.1"
                     /translation="MSNSVQSTKVVTGKVRLSYCNIFKSRAMVEGAEPKYSVCILIPK
                     SDKVTLGRIKKAIDAAKEQGKTSKWGGKLPGNLKTPLRDGDAERADEAEEYVGMYFLN
                     ANSTQKPGIVDKDLNEILDNTEVYSGCYGRVSINFFPYNSAGNKGIGCGLQNVQKLAD
                     GEVLGGARASAEADFSDDFEYEDEEEDFLS"
     gene            complement(23739..24311)
                     /locus_tag="KRQ43_001869"
     CDS             complement(23739..24311)
                     /locus_tag="KRQ43_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="HBH2742225.1"
                     /translation="MSNQEITKLVENNLNLVHFSINRFFKSYVEQHPYLYEEFYQEGC
                     IGLYKAALNYDSNRGKFSTVAVSYIRIEMFKALRYGEKHYRNSIEGLDVSVFEDSKRP
                     LKDIHGFYEIQFNYDVDYIRKIARKSYLKDIDKIVDWILQDKKISDIGELLNVSSTVI
                     CGRIKLFSKQVRDLDKFGEITSNIKSIYQI"
     gene            complement(24364..24699)
                     /locus_tag="KRQ43_001870"
     CDS             complement(24364..24699)
                     /locus_tag="KRQ43_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742226.1"
                     /translation="MPLDAGIKDKLDESISIILDLKDRKKSIEKDLDYEKDNLLDMLK
                     RLNITEYNSTEENAKVIVMDFKRESLIKDKVMSTFLEVNDNHLDRVYIPEHIKVSPVC
                     FVSVRAKDN"
     gene            complement(24714..25880)
                     /locus_tag="KRQ43_001871"
     CDS             complement(24714..25880)
                     /locus_tag="KRQ43_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HBH2742227.1"
                     /translation="MPLQHARLSASGAHRWLHCTPSIKLEENYPPLTSIYAEEGTVAH
                     ELAEVKLMLEYEKISKKAYNARIKKIQKSEYYNSEMEDYIQSYVENVVELVNDSKAIC
                     DDVIVMLEERLDFSEWVPEGFGTGDVVVISDGILQVIDLKYGKGLEVSAIENPQLRLY
                     GLGAYNQFEMLYDIDLIKTTIIQPRLDNISSEEIEVTKLLTWADNVKKKAQMAFNGEG
                     EFVSGSHCGFCRAKNDCRKRAEDNLKLARKYDFADTFALNKYEIADILGFAKNIQDWL
                     KDVQSYALEQAEKHGVKYPGYKLVEGRSNRKYVDEQEVAKVLLNSDYDEEKIYKPRTL
                     KGISDMEKAIGKKSFAKLLSDLIIKPVGKATLVVESDKRSEINSIDSAKKDFEI"
     gene            complement(25892..26329)
                     /locus_tag="KRQ43_001872"
     CDS             complement(25892..26329)
                     /locus_tag="KRQ43_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742228.1"
                     /translation="MVEVNVNVKVKVEAPEFTNALLVVANALGGLNLGKAMQIEPINI
                     TDMKEEKKVEVKKAEKIKKVEVKEDVKEEIAEAKEEIEKNNENTTSEVKYTKEEVRTK
                     AAQVSKAGKKDKLKELFGEFGASKLSEVKEEDYSAFMNKLESL"
     gene            complement(26400..26543)
                     /locus_tag="KRQ43_001873"
     CDS             complement(26400..26543)
                     /locus_tag="KRQ43_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742229.1"
                     /translation="MLSLDTNNKNVVTLKKDGKVIADIVFKDIKTGKKISVGILNKKV
                     LVK"
     gene            complement(26530..26922)
                     /locus_tag="KRQ43_001874"
     CDS             complement(26530..26922)
                     /locus_tag="KRQ43_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2742230.1"
                     /translation="MDISESIAKQFSDSLKSLIEIEISKQETDRVKSQTIEQKVKVLE
                     PKDIVVLIKRGYPNYLITVEEARGILKLDTAFMRRLVSTGLIKSLVRGDGRKISRYEV
                     DDFIERNQGKNLDELLKAVEWGDEIAES"
     gene            complement(26953..27150)
                     /locus_tag="KRQ43_001875"
     CDS             complement(26953..27150)
                     /locus_tag="KRQ43_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2742231.1"
                     /translation="MLIGDNIKQMLRKRDIKPYKLAKELNIDVSGLYKLLRNKSSNPT
                     IDTLIKLADYLDITLDELVGR"
     gene            27226..27600
                     /locus_tag="KRQ43_001876"
     CDS             27226..27600
                     /locus_tag="KRQ43_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742232.1"
                     /translation="MQFSNNISKELQESIRKTVSDTSNTEYFYYAEFQYKIILKSIEE
                     FEKELDDEHEIALKLTNFGKDVLMIVEEVGYHNPCLIHYYGIVNGVYSEILQHTSQIN
                     FMITSVKKTDPSKPARRIGFIL"
     gene            complement(27610..27819)
                     /locus_tag="KRQ43_001877"
     CDS             complement(27610..27819)
                     /locus_tag="KRQ43_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742233.1"
                     /translation="MENKKIEEIEKRITMLENQLQAQLFSQITAQSNSDFIDYMYQCI
                     VLYLHEMNKSEKRKISEITKERIRK"
     gene            complement(27866..28675)
                     /locus_tag="KRQ43_001878"
     CDS             complement(27866..28675)
                     /locus_tag="KRQ43_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBH2742234.1"
                     /translation="MNNLQIFKNKTFGEIRVIELNGEFWFVGKDIAEQLGYKDTSDAL
                     KRHVDDEDKGVGEIPTPGGNQNMKVINESGLYSLILSSKLPSAKLFKRWVTNEILPSI
                     RSTGTYNMIDLQTKLPTTYKEALQHLIEQVEVNEQLQLESKMKDQVIKELKPKADYTD
                     MILKNKGLVTITQIAKDYGMSGKEMNKILHERGIQYKQSGQWLLYKQHQGKGYTHSET
                     IDITRSNGMPDVKMTTKWTQKGRLFLYDLLKTNNILPDIEKGYSYQTSILG"
     gene            complement(28723..28926)
                     /locus_tag="KRQ43_001879"
     CDS             complement(28723..28926)
                     /locus_tag="KRQ43_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2742235.1"
                     /translation="MKKRSLKAGRIEAGYTQEELAYKIGIAKSTYNLKENGKRNFTEK
                     EMIMISYILNKTMDELFLEKRLT"
     gene            29103..29444
                     /locus_tag="KRQ43_001880"
     CDS             29103..29444
                     /locus_tag="KRQ43_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH2742236.1"
                     /translation="MATFGERFKQLREEKKLTQDELVSKFNKVYFTSFNKSTISQYEN
                     NKRKPEINILENWADFFDVSIDYLLGRTLVRNHIDTVAAHRVNPHKDLPEEAQEQLND
                     YIEFLMNKYKK"
     gene            29456..30004
                     /locus_tag="KRQ43_001881"
     CDS             29456..30004
                     /locus_tag="KRQ43_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2742237.1"
                     /translation="MLILKKLRTEKGISLDKLSTDLNINKSTLSRIENGLREPKESFI
                     KDCSDYFGVSTDYLIGKINIDDSNKLTKCLNSTFPIRLKELRKKKELTQAELSKLLNC
                     SLSKIAMLETSKREPVKEDLLRISEFFNVSVDYLLGKTSIENYITTDEISKIIKSYES
                     LPKEAQEHINSYIEFLVDRYKK"
     gene            30080..30586
                     /locus_tag="KRQ43_001882"
     CDS             30080..30586
                     /locus_tag="KRQ43_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBH2742238.1"
                     /translation="MNKLDALLDLANNEEIEIYYTDKIADDIKGLYINRQGLKIISLL
                     NSLKQNNAKLIEILAEELGHHFTSVGNYVSSKNSYKNKILIDKTENKALKWACEFLIT
                     EEEIIHVINSHATSVYEIAEELQVSINFLLKRLEFLSKKKSMLDLGNNRFLVLTNLPN
                     FYIYEDIF"
     gene            31206..32075
                     /locus_tag="KRQ43_001883"
     CDS             31206..32075
                     /locus_tag="KRQ43_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HipA domain-containing protein"
                     /protein_id="HBH2742239.1"
                     /translation="MIKNFDEWKEYDGFSYGSGRSEKIWLINEKTKDIGLFKFPKTKE
                     TGEYWAEKLACEIASLLKIPCANVEIGTYNKRIGSMSYLINKNDEKLIEGVWLINKYY
                     PCYNTDKLYDYKNNEYYSLKMIFKSIEEYNIKNDFLKMLIFDYLIGNRDRHQNNWALL
                     ESQNKITLSPLYDNGSSLCCYVNIENIDSFFTDHQRFEALINTRSRSRIRIDGKNKKE
                     PTHLEVLKYLNSNYYEQTIDFVEKIINLMNEVNINTLIDNYSENIISPKLKKLLKIYL
                     KEKVLRIKNIYNL"
     gene            32088..32795
                     /locus_tag="KRQ43_001884"
     CDS             32088..32795
                     /locus_tag="KRQ43_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBH2742240.1"
                     /translation="MSIKNGKDFLYVIWKDPKSRRQFIIGKLAKNGLYEFSYEYEIDE
                     AIKAGFNALISFDDISKTYYSEDLFSPFASRLPDKKRKDINKILDKYDMSEYDTYELL
                     KRSGARLPIDTLEFVDPIPLDIDKNIIRYFYIAGVRHYAGCEGHECDNSIELESNEAL
                     VLELEPENKFDPHAIKVFDKKENHIGYIPRYYSGELTSIINRGLKYNCIIKFVNKENN
                     CDECIKVKLEILFDEYN"
     gene            32874..34004
                     /locus_tag="KRQ43_001885"
     CDS             32874..34004
                     /locus_tag="KRQ43_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH2742241.1"
                     /translation="MKGGVRKRSNKWYYYFDLGIVEGKRKKVERVGGNTKKEAEKALR
                     EALNEYENSGIVFEESNISLSDYLDFWYKEYVLLNCKYNTQESYRINIEKHIKPKLGA
                     YKVKALTPAILQNFINKKYKEDYSQNTLQVLKAILHRSLKSAVHPYKHIRENPMQYVS
                     IPKTKSKTETNKVKTITLEEFNQILNIFPQDSFQRIVLLIGFHTGMRRGEIIALKWDN
                     IDLDNKTITVKHTLIKKPNGMFELGQPKTESSCRTIFTGDTLIKALKEHKLYQKKMKL
                     KYGEFYFDSDWVCTKENGQQVNTHTLDTIVRQIRVALNNDFHFHSLRHAHATLLLENG
                     ANIKDIQNRLGHSQLSTTMDTYSHVTDKMKNETVDIFEKITN"
     gene            complement(34362..36050)
                     /gene="ilvB"
                     /locus_tag="KRQ43_001886"
     CDS             complement(34362..36050)
                     /gene="ilvB"
                     /locus_tag="KRQ43_001886"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HBH2742242.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKTFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWSAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKAGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSNMEELGKVLDVIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            complement(36103..37098)
                     /gene="ilvC"
                     /locus_tag="KRQ43_001887"
     CDS             complement(36103..37098)
                     /gene="ilvC"
                     /locus_tag="KRQ43_001887"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBH2742243.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            complement(37368..37607)
                     /locus_tag="KRQ43_001888"
     CDS             complement(37368..37607)
                     /locus_tag="KRQ43_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH2742244.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     misc_binding    complement(37720..37977)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(38138..38899)
                     /locus_tag="KRQ43_001889"
     CDS             complement(38138..38899)
                     /locus_tag="KRQ43_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBH2742245.1"
                     /translation="MNTGSKDIDTLNVNFRGIEIKAVLVYKNRKNISIKIDPFGKIIV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKYKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLKDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERTVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     gene            complement(38904..39725)
                     /locus_tag="KRQ43_001890"
     CDS             complement(38904..39725)
                     /locus_tag="KRQ43_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HBH2742246.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANYER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKRETGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            complement(39767..40522)
                     /locus_tag="KRQ43_001891"
     CDS             complement(39767..40522)
                     /locus_tag="KRQ43_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH2742247.1"
                     /translation="MTTYKKLKKSIFKISIFSICLLVSLVDINPIFAGSSSNETSNSD
                     TIKVLNAKSLNFKQGNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEDSSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDFPVKDFESINKYQDFYFNKN
                     GNLVISFEEYEVVPGYMGAVEFVIPNKVIKRLR"
     gene            complement(40565..41434)
                     /locus_tag="KRQ43_001892"
     CDS             complement(40565..41434)
                     /locus_tag="KRQ43_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH2742248.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGVIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKAHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            complement(41446..41928)
                     /locus_tag="KRQ43_001893"
     CDS             complement(41446..41928)
                     /locus_tag="KRQ43_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2742249.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            complement(41980..42912)
                     /locus_tag="KRQ43_001894"
     CDS             complement(41980..42912)
                     /locus_tag="KRQ43_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH2742250.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKEYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            complement(43005..43838)
                     /locus_tag="KRQ43_001895"
     CDS             complement(43005..43838)
                     /locus_tag="KRQ43_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH2742251.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
BASE COUNT        13680 a         7948 c         4564 g        17890 t
ORIGIN      
        1 aactacaatc tatttgacag tagagtgaag ttcataattt aaacaattag taattattta
       61 aatttgtgga acttgatttt aaaatcaaat tcccagccac ttttactctt gccacgagtt
      121 gagtggcttt ttacttttag aaatacttta caaattaagc aaaatattaa actagcaata
      181 acgccagcta ttacattaag taaaaagtta ttcatacttc ccacctcctt tcattaggaa
      241 gtaggtttta tcccagtatg aactccactc tataaattgt agattacatc ttcttgctaa
      301 aaatattata acatataatt attacatatt ttacctattc tatatttatt tttttatttt
      361 gctatcttct tcgtcccctc tttctctctc tttcagcttc tttcattgct tcctcttcat
      421 cttctatctt tataagtatt gaggcggctg ctaacgctct ctcattaact tctaaattca
      481 tatattcact tggcttccac tttaattttt gaatacaata atgagtgatg ctagcatcaa
      541 aatcgccacc tctgattagt tttttgcttc ttctacttta tcctcaaaag atgtatcaaa
      601 tccattgact tcattcactt ttactgtata attgacatac tcacctgctg taagcattgt
      661 ctttaataac tgagcttctc ccattactcc ataactattt tggagttcgg catcctttaa
      721 atctggaaat actgtagatg ctacacataa ttcagctaca taactattgt agtcaatttc
      781 acttgtatat tgtccagtat gcttaccatt gttaccaatc acttttactc ttttagtaca
      841 ctttcttctt agtgcttcgt cttcttcaga tgataaaact tttaattccc attcaactgg
      901 tttcccttct ttatctaaaa atctgttact cgctacatat tttacattat caacctttat
      961 tgcattttga cttaaaaaag cacttaaatt actcatatta ttctaatctc cttttatttt
     1021 aatttttcat ataaaaaata cacatttata acttataaat gtgtatttta ctccatacct
     1081 atatttttta ttacttcttc caatggaatt tttttagtaa ctaattgatt ataaagaaat
     1141 agatacttaa cattcaaatt ttctgcacat tgttttaaag taatcatttc acctttataa
     1201 ttaactctaa tactatttct tttattattt cgttgaactt cccaagtaac ccatctacaa
     1261 tttgatggtt cgtaatttcc attcacatta attctatcta ttgttaaacc ttttctatat
     1321 ccattttcta tagaccagtt ataaaaattt ataaaatcct ctagccattc attgcatact
     1381 tctatgcctc tacctccata ataattataa tctttattac tcttatttgt gcacctttta
     1441 atcatacggt gataaactct atataagcta tcattagatt tattatgcgt tgtagagcgc
     1501 tctagtaata tttcctttct tatacagcca caactttgtg cttttccttg ttctaatgca
     1561 cttgtactag ttattgttct atttccacat tcacattgac ataaccataa attgtgacta
     1621 tatttatctt tcccagacat tttcaatact gtaagcttcc caaaagtttt cccagttata
     1681 tctttaaatc tcttattttg tcctttccag tttggagaac aaccacaatg tggaggcttc
     1741 tcatttttaa ttgattgctt taaattattt tctactctct caactttatt cccacactca
     1801 cattgacata gccagacttt tttactatgt ttatttctcc ctaaatattt aattaaagta
     1861 agtttgccta atttaattcc actttcaaat tccatgaaat acctccaaat aatttatact
     1921 tacatcataa tatttttcaa gtataattca attttataac attccattaa gtaatgcaaa
     1981 ggattcaact aattcccaat cctcaaaagt gaaatccata tcttcatcta aatactcacc
     2041 atcagcatca aatttagtaa ttattccact gtccatatta caatctttaa gtactactgt
     2101 ctgtcttcct acagcagatg tagggtcttc atttgtaact tgtatgtcaa aataaatatc
     2161 ctcaccagtt tctttatatc tgtaaagtaa ttctctaaaa atagaagtat tataatgaaa
     2221 tgttgcactt ccagtatttg tactcccagt tgttttattt ccctttgttg ttcttcctag
     2281 aattggaact tcacttttat ttttttccat tttagcctct aaatctatag cttgcataaa
     2341 attatatctt ttaccttcta tagttataaa acattcagct ttctttgcac taactgtatc
     2401 tttagcattt attgtttgag ccatattatc actctcctct ctaattaact gaaacagtca
     2461 tataaagctt actcatagca tttattacct taatagcatc agatactatg acagttttct
     2521 tatcatttcc aagctctaca ctaacatcat cagttttaaa atcttctatt gcccttatat
     2581 tctctaattc tttatggtgt ttaacaacat cattccagaa acttattctt cctgccttat
     2641 cattcggaac tttacctaaa tacttttcat taaataaagt tgcaatatca ttagcaattt
     2701 ggtcaagtac tctaacactt tggttacttg aaaaatcgtc atttttatca tctgtaaatg
     2761 atacaaaagt atttatatcc tctaacacat gaacttcatc tcccaccttg tggaatataa
     2821 atttaccagt ttttaaagct tcttcaagtt gtatttgtgt ataattaaca tcaacatcaa
     2881 actcaccatc atacttttta ttagtattag atttatttat atcgcatcct gctatagctc
     2941 cagtagccca ataaatcaag ctagattcaa ctaaatcttt atctttaatc ttattttcta
     3001 tagacactac accttcataa tctgcatcac ttttcttata tagtactgtt tgaaacttag
     3061 ctcctacctt atctctcatt ctctttgtaa attctacaaa taaactttta atttctgttg
     3121 ttgtagccaa acaccctagt gcattaaatg aataactttc tattttatcc aagaaagctt
     3181 ggtactctgc tcctgtcaca gcttcgccat tggttccacc agtaaataca agtcctgcac
     3241 ttgcttctag tgttgcatcc ttcttccaag tgatatagtc attgtcttgt aagtctgtaa
     3301 taacctttgc tatttgagta tctaccttct tattatctaa aagtattaca acatcaaact
     3361 tagcattatc atctatattt gttgtaactg ttacttttaa gtcatttcct cttataccac
     3421 tatattttgc tgtggctata gtacaactgg ctttaacgcc tttatttaat ttataaaaat
     3481 atcccaacct tatatttttg aataaatctc tcaaaccttt cagcttctca tgagtataat
     3541 catatccaaa atacttcact gaatacttct caaaatcatc actggttact tggaatgctt
     3601 cttcatctat gccccaatct aactctaaag gcattgcaac aatacctcta tctgataatg
     3661 aactggttgc cctcttagct gagataaaat ttatatatgc accaggaagt attttatttt
     3721 gcgttacgaa tgttcctcca cctaaagcca tctaactcac tcctttcata aatttattta
     3781 ttctatcctc tacctctgag aaggaatata actcattttc ttttaaaatt gcatttaata
     3841 aatcttttct atttacatac ttcttagagt taactatctg ctccttagta aacttgtagt
     3901 tatcttcttt gcttaatgct ttactcaaaa ttatcacctc tcttcaaacc accgaataac
     3961 tctactgtat ccatcttatt ggtatcatta ttttttatag taaaatagtt ataatcaaca
     4021 aagaagtgaa gaacattgtc tataatttca aaattcatat ttgtacctct tactaaatct
     4081 ccatcaattt ctatatactc taattcctcc agtagcatct cagctatctc atttatttca
     4141 aaattcttat cttctgaacg agggaaataa tgtacatcaa aagaattttt ctttaattct
     4201 ctcccgcttg gatatggtgt cttgcttgga tttaaaggaa caataaaaaa acaaggttca
     4261 ttaatacctt gctccacatc ttcgctataa attgtatatt tttctccaaa cgatttatct
     4321 aactttactg atattccatc tataatatta ttaagcatca aacactcctt taagcaatat
     4381 taatagtttt ttctctatta tcttatcaac ttgactttgt agttccattt ctgaaatagt
     4441 taagaaatgt tgtcctttaa cccaaccctt gccattttta gttctatgac caaattcaac
     4501 atatgcattt tgttatccta aaggcttttt atcctctagc tcttatagtt tcctataagt
     4561 tcggcgtaca tcatcaacaa aataaacttt atttagttgc ccagcactct tggagagatt
     4621 atatttattc actctctacg ctctacggaa acctatagcc tatccgcaat ctataggttt
     4681 tcctcggtat tggcatatat aattaattaa atatttttcc atgttcttct atggactata
     4741 tttgatatag atgaatatgt tacaggatat atttcactta gttgttttat tgtatatcca
     4801 tcagaatact tttttctaat ttcttttaca tcctcaatag ataacttagc tctgctttct
     4861 tcaataatct taactttttc tataagctta tttcctacta atcccttaga atatctactt
     4921 cttaagcaag agtatgaaat acctgttttt tcagaaagct ctatcaatgt aatttctttt
     4981 tcttcatgtt ttactaatat atttgttgac ctatttctac attgtgtctt tatatccacc
     5041 catctacaat tgcttgattc ataatttcct tcattattta ttctatcaat tgtaagtttc
     5101 tctgaatatc cattactcaa tgcccaattt gcaaaattat catagcaaaa ccattcatca
     5161 cacacaatta tattcctttc accatatcta ttgtatcttt tattattttt atctgtacat
     5221 ctagatatta tacccttcca tatactgtaa agtcttttat tttgaacctt atatttcttt
     5281 ttaaattggt atttgtctgt taaatttaat ttatcttgtt ctttttttaa acatccacaa
     5341 gattgcacta agccactagt taaagagtca gttcttattt ctttgaaatt tccacaatca
     5401 cacttacata accaatattt cctatttctt ttaccgcttt ttatctcttt agaaaattta
     5461 atgactctta gccttccaaa tttttttcct gtaatatcta aaaattttgc cataaaatca
     5521 cctcttttat acattataaa tcaagagtta ttctatgtcc atattctacc tactttataa
     5581 tgtaacacta ttacacttag cgtttaccga ttttgctggg ttttatatgc cccattgtgt
     5641 taaggcatat tcagttggat taacaacttc tataatataa ttattacctt gtttgtaaac
     5701 aggaagcgac ctagcataag ctactccact ccaaccctct ctcaaaaatc ctgtatcaac
     5761 tggtgtcctt ctaattactt ttcctaagag tcttgctgct aattctcttg ctgcatcctt
     5821 gcaaaactta tctaaatcaa tctttgtaaa tttctccatc tttttacaaa ctcttttaaa
     5881 ctctctaaaa tcaacactgc cccatctagc cattatgctt tatccttaaa taactcaagt
     5941 attatttctt gatgatttgg atatatagct gattctccac ttcttacata ctctttatca
     6001 tttataataa gttttgaacc tgctttaatt tctatatctg gagatataaa gagtttaata
     6061 gtttgctcta gcttagctaa tttcccttct gtagcagaaa ctatattttt atatgaaagt
     6121 ttacatggtt gattttctaa tacaatcact tctttattgt tagttcgttt tgttacaggg
     6181 tctttaattg gctgatactc aactatagta catttatctc tatataacat ttctattgct
     6241 tttctagttt tacttaccat cttaagcacc taaaggttaa tatcttattc ttaccataag
     6301 tagtaagata agctattaag ctatcaaagc gttgttctgg tgtttgagaa ccacttccta
     6361 tagcaaaatc tacctttgta tcaccttctg atatagactt ttctacagct tcaaagttaa
     6421 tgctttctat atctaattga cccatatttt tcttggtaaa taagaactct ccaactatca
     6481 tatcaacttc aatttctttc aattcaattg gcatagtttt tatattacaa tctagtttaa
     6541 taatattttc tattttttct cttacaaaac ctattaacca cttatctcca tcttttaata
     6601 tatatccaaa actttcaagt cttttttcta tttcatcaat tatattattt tccataattt
     6661 tcacctactt tttagtaagt ttatttttct ctttaagctg cttattttct tcttctaaag
     6721 actcaacttt tgaccttaaa atattatttt cagctattaa atcttttaca cttaatgact
     6781 tgccatactt tactgcctta ccagtttcat ctatcaaatc atatcccatc tctaagaaat
     6841 catctatttt acattcttct atggttagta ttctatttag tttttttact tgtggcacta
     6901 tatatcactc ctttttctat gcttcaacaa caaattgtat tgcatcagct tttttattta
     6961 atataaatac atcctcaaaa ctttcttcaa agtagaagta ttttccctct gtaactgctg
     7021 ttggttcgtc taacttagag aactgataag aaacaggtgt aattattgca cttgggtgaa
     7081 ctaaggacat aaagatttgt ttagctcctg ctcctacttt ccatccagtt gtaaaatcat
     7141 atgcagtttt cattagatta gatggtactt taattatttt aactgtgtca atatctgtgg
     7201 tttgtctatt taaagaagtt ccaccatctt ttatgtttac tgttctttgt atctcttttg
     7261 catttttgat aagtgtattt actactggag taacatacaa tattcttcca ttttcaggta
     7321 ctctagcttc tgtcattttt tccattaact tatcaaatac ttctaatacg tttgctgttg
     7381 taagaacagt tgtatctgct gtgttaccta atgcggtcca atcagcatat attttagata
     7441 tacagtaagc atccatctct ggaaactttt gttcctcatt atatactttt gttatattac
     7501 ctattgaagc cacataatta gtttggttta tatctgctgg atgaaccaat gttgaccatt
     7561 tcctttgatt agttaatacc ttaggttccc aagcattatc atagtttctt tgagctactg
     7621 ctattgtatc tctgtttgaa tctacccttc cagttgtaga tatagttggt atttctattg
     7681 ttttagaacc cgtccatcta tatcttccat tattttctgt tgcatacaaa tccccgaagt
     7741 ttaaagtata aggatatgct tgtgctaaaa catttgaata ttcttttgca taatttagtg
     7801 ctgccatttt atttcctcct atttattatt attttcatga ggtcttaccc cagtaaaatt
     7861 aaaaccaaaa tcatttatct taggctcttg ccctggtgtt atagtatcta ttttaggttc
     7921 ttcaccttct agtgttgcat taaacaaata atctttatcc tgtttcaaag ggtttatttg
     7981 ctcttcaaaa gctttttgtc tatctttact atttcttagg gcttccatgt ctaaatgagc
     8041 ttttaacgct atttcatctc tacatttaac agatttaaaa gcatcaccta accagtaatt
     8101 aaaatctttt tcttcaattt cttttttgta ggtttcttcc aaagttttct tatcagtttc
     8161 ataagttgtt tttagattct ctacatcttc ttttgtcata cctccttcaa actttttaat
     8221 agtttcatta gctgtattaa gttgtgtttc aagatttaca taatcttctt gagtaactgt
     8281 agtctccttt attttctttt ctatagattt ttgaagagaa gctacatcaa ttttgttatc
     8341 ctctactttt attccttcta gcaattcttt taaccaatcc attttaaatt tctcctttca
     8401 ttttttacaa aataaaagca cctactaatt tattatttag caagtgcttt tacatattta
     8461 ctatttgtat atctttccat aaatccttta gtaatttacc atcaatgttg taattatcaa
     8521 ccatatcctt accattttta taatactttg tatctccatt agggcaaaga gtaataaacc
     8581 ttgtatcatc atctccaata gatatattat atggtttatt atataagtca aattctatat
     8641 ctaatcctaa atcaatagaa tcaattaaat gttgtaaatt cttaaattta ttatccattt
     8701 tattctccat tcaaaatatc tttgttagct attttatgag cttttgtaag ctccatatcc
     8761 ttctctcttt ttaccttatc atggttattt tcatcagcta accaatcatg tttatgaggt
     8821 acaattttat gttgctttgg gtttctatgg tcagttaagt ctaaatctaa tctaggtttt
     8881 cctgtattac catagtatct tctttgaatt aatttaccat ctttgtaatt atcaaataca
     8941 ctatttggtt ttgattcaaa tggcactgaa tgaacacttc cactagttaa atttctctga
     9001 ttcttaactt gccaatttac atccttataa agctttttag cttcctcata ccttatagta
     9061 tcattatact tcatatgttg atattcatca aatttagaag gtatttcatt tcctaatacc
     9121 tttttatatt cttcaaattg ttttctatct ttactctcat ttagttgcat ttttctaagg
     9181 gtgtcagctt tttcttttcc aagtctaccc tctatatgtt tctcatacca ctcattatac
     9241 ttcatactag atggtacata atatgttttt ccatcttctc ctcttgctgc tctatagcct
     9301 tcttcatcct cgaaccaagg agctgttgtt gtcctacaac gacaatgaaa tggtggagct
     9361 gttattccaa cttgataatc tttcatatca aatatttttc catctaactc tctgcatata
     9421 tttgaagttc ttaaatctaa tgtagcaata atctcatatt tctctacatc taaatcacta
     9481 aaacaatctt ttctacttgc tgatgcaaag aaagctgatt cagtcattat caaattctta
     9541 gcttgtgatt tagatacatt aaatctctta gcaaagtcat ttactagatt ttttggattt
     9601 tcacctctaa taattgattg agttagctta gtatgtagtt catttattaa agtaggtcta
     9661 tgcttacccc aaattctttc actaaagttt aatccatctg ttgcccatgg tttagagata
     9721 attttattta ttctattagt atcaagactc attaaactcc aaccaacgtt tactccttgt
     9781 tgaacattaa aagctgtatg atagtatcca cttgtataaa tatctctcat tagtttatca
     9841 ataccatcaa gttcatttcc atataaaact tctacgtgtt gctgtatttg taactttaaa
     9901 gcttcaagcc ttgttatatg aagtcttgca ctagcatttt ctaactcctt catccacttt
     9961 tgatttatag cattttcttt gccatattta atatactctt ctacattcca cttaaattct
    10021 tctaattctc ttgtatttaa cagtttctta gcttctaata aagatattcc ttcattttca
    10081 gcaaatctgt tataccatga taatatatct ttttctatac tattcatagc taatttgtat
    10141 ttcttttcca attcaagata atattttaca cttttattgt tttgaacttc ttctaattgt
    10201 tcaaatcttt tcctccaata atctttatgt ttcatctata acaccctctt gattattagt
    10261 aggaattaaa tcatcatatt ctttttgggt ttcttcctgt tttttaagtc tttcaagttc
    10321 gtcattaaca tcttcaaccc aaggatgatt actaacaata gtttcatctg atataattcc
    10381 aattgattta gaagccatat ctattttttc agactcattt attatcatag aatgattaaa
    10441 tgttatttga actgacttat aatcatagct cttactacca cttatcttta aatactcaca
    10501 cacaaaccat aaaagctctc taattgcttt tttaaacttc ttttcagtct tggaacattt
    10561 taaatcaagt agtgaatata aaaatttaag agctacaccc gatttgtcac ctgtgttttg
    10621 agattcggga ttaactcctt gaccaaaaat aattatattc ttttctaatc tatcaagaag
    10681 ctcctttttg gcttcaactg gtatatttat ctctagttta tcaactccac ctccaccatc
    10741 tactttaatt gatttatagt atcttatatt atctataaac tcttgtagac ttgttcctgg
    10801 atactctttt aatacataaa tgacctcttg catttcatct aaattgtctg caagtgtaga
    10861 aatgttatta tcatatatat caattaaaga cttatagaaa gttaaatctg agacacactt
    10921 ttcattattt ttaaaaggta taaatggaac tttaccccat ccctgttctt tgttatttat
    10981 tctaaaatga ccttcttgta tatcagtcat ttttccatat tcatcatata aaaattcttg
    11041 aataaaacta ttacctcttt caataaagta agttacgtca ttttctgtgt agtactcaac
    11101 tctttttatt ttatttccat ctatatcttc aatataataa aacctaataa atgcaactaa
    11161 ttccctctgt cttttactat cccaaatagg aattgcttct tcagctggaa ttattacata
    11221 tttaaactca ccttttctat taatatatgg atgtaaccat tcaacccctt tattactagc
    11281 attgagatat agttctgtta ttgtatcgtc aaactcttct cctagtaagt catttaaaag
    11341 cttagtgaga ttatcatcat ctgcattaaa tactatggga tttccgacac tatagcctac
    11401 cttttggtca actaaaagct tatggtagtt gttaattgct ttattattaa ctttagtaaa
    11461 atcatcaacc ttagctccat ctaagagata atatcttctc ttattgttta catcagtatt
    11521 accataatag tattcttctc cttgtttata tttttctggc ctatgcttta agatgtagtg
    11581 ttctatgact tttactaggt taaaggtgct ctcttttttt aactgaactt ttattaaatc
    11641 tgtttcactt atataaatat ttaacacctc ctttacttta agaagcttat tccattattt
    11701 ttaagcttat tatctataga atatctaaga gcagccattg catcatccat aaactcaact
    11761 ggttcatcaa gatataatcc agttctttcg tcttgtttcc atttccattg ttgtatttct
    11821 tttatggtat tagtgcaact aggatgtaca tgtattctta attgtttcaa ataatctatt
    11881 tgagctttaa cacttcctgg tcctttttta actcctttag ctttatatcc tgcactcttc
    11941 cacatcttaa ttctatctgg ttcagcacta tcacagtaca taaatagagt cttttctaaa
    12001 cctctactat ttgcaatttt tatgatttct gaggtatcca tttcatgtac atatatttca
    12061 ttacatatat ataactctcc atccttaaag ccaattctaa gtattgcatt tgcatgatta
    12121 aagccaaagt cttgtgacag tctcatattg tcaaagtatt caaattctgt gggaaattca
    12181 tgtataacat aatttttaag tattgctcca ccagtttctc cccattctcc aagaccatat
    12241 actttgtacc cttctgggtc ttgctctttt ctcatttgca ttcttctgta gtaagcttca
    12301 tctatgaatc tattttgtag ataagtacta tgatgagtaa atatatcatc atttttatag
    12361 tcaaaatact ttctttttat ccaatgagta gctgagactg gattaaatgt aaatgtcatt
    12421 tgataataca agttaggatt agttaaaata cctcttaaac ggtcatctag tatatctatg
    12481 tcactttcca taagttctgt agcttcttca caccaaaccc atgttaattt tcctttcgag
    12541 aagttaattg attttaattt ttctctttgt tttgcatcat taactcctct gaaaattata
    12601 gagttaccag taactttact cttaatttct aaaggattta aagtagtttt ccaatactta
    12661 tcagcttgtt taccataaat acgatttata gctcctgtaa gctctgcata cgttgaatac
    12721 ttatgtgtag cttctgactt tctaactact aatagattag ctccttgata cttcttatct
    12781 cctaacttta gtatatagtc ttgtgctaca ttaacagatt ttccactccc tgctgaacct
    12841 ttcattgctc tgtatctttt tttagtaaaa ttagcttcct tgaaatctgg attaaaattt
    12901 attctaacta tcatttctat caccataatc tacacttatt ttcaactcat catctccaat
    12961 atcatcttta tttaggttag caacctcaca tttcaacttc tcaactcttg ttttctgctc
    13021 ctctgtagcc aaattccaat ccttatgaat catttcatca tactgcttaa ttaaactcct
    13081 taactcactc atagctctac tctgtgcatt aagaaaagat gcttgcctat cccatgcaaa
    13141 ttgaaattca tactctatct tctcactatt ttctgtgatt tcatgtttct ttaattcctt
    13201 aatcatttcc tctttatctt taacatacat tatcttctgt gctcttatta ttgctgcgta
    13261 ttgaattgtt atctgttccc aaagaatatc aaatttatct tttatagata tttcttgtat
    13321 taattcccta gtttcttcag gtaagtattt tgagaagaaa ccaaactttt cagcattttt
    13381 attctctttt ggagcaccat aaccaactga atttttatta gaaaagggtg cacccctttt
    13441 atttataggt gcacccttct ttttttcact agaccaattg tatcttttta tccatgactt
    13501 taaagtattt aaactaatgt catactttgc tgatatttcc ttttgtttca ttccttttaa
    13561 gtaatcttgt tttacctttt ctttgacatc ttgcacatca ccacctcttt atttgtttgt
    13621 tttgggaata aaaaaacaat cctatttaat aggattgttt caaatctagt ctcctctatc
    13681 cttccaggat aaatgaaaca tacttattat taatgtagtt agagataaaa ttatatgaac
    13741 tgtaaaaaat attaaaacat agaaaattat attagaataa tatcgagtaa gcattattgt
    13801 attgataaaa catattacaa caaccaaaat ctccattatt acagtataat atgcttttaa
    13861 ctgtatgaat tgaaagtatg atatattaaa tccatttacc tttctttctg tttttatatc
    13921 ttttgcttct gatattgatt tgttatatgt agtaaacaat aatgtaataa tgcaaactcc
    13981 aaaagctact aatagtcctg acaaagttag tacatctttg tttaaagaaa ttacaacttc
    14041 tttattaatt gacgaattaa aaaacatgta tgaaataata catattaata ctggtgttaa
    14101 aactaactct actacttctt tagaatttat agccttgtaa taattgagta agatatttaa
    14161 taccttttta tacattttaa cacctcctta gcaatctatg cttcactcat agcaacttct
    14221 tgatacatta aattaaaaaa aactgaatta ttctcaatta aatcatctat caaattattc
    14281 atcttctcaa aaatgtcttc actatctata tgattatcta tatcaagaga aacctctatt
    14341 tctctacaca actttatacc ctcagtatcc aactttaatt ttctcttatt tttctctccc
    14401 tcaattatta tcctatttat ttttttattt ctaaattcct ctcctttaat atatttttcg
    14461 caacatcttt taacttcact aggtaaatat ctagttctaa atgtgggctt atatatcaaa
    14521 tcgttatgtc gtcttgaatt atttaaatta gaaaacaaat tatcttcatc agttccaaac
    14581 ttctctctat caacatttaa agttattttt gaaacaccat ctaaatctaa tatttgttct
    14641 ataaaatctt tacttgctat ttgtgtaata ttaattgatg tttttgacat attattatca
    14701 aatttattat tttcaatcat atcctcataa tatagatgta agtttttact tagttcaatc
    14761 atgggaaccc ccacaaaaac tctttcaaat aatactactg ctatattatt ttccttcata
    14821 aatttaataa ataggtgctg cttattgcta tctccttgat ccattttttt attaccctct
    14881 acttctttag tatgagcatt tataatattt gtattctgat tgtatttagt atattcaagt
    14941 ttcaccttga ttattaaatc atcctcgcta cattttactt ctgtaatcca aaacttttta
    15001 tctttagtaa tattaattcc atttttgttt tctttacaat attctttatc cttaaagaag
    15061 gtctttatta cctcttttaa aatttcttca tctgaataga cactcccatt aattttattt
    15121 ataatatcta ttctataaac atcaatatat ctttttttaa aattactcat tataccatta
    15181 ttcctttcac aaatatttat aatgatataa ttctatataa tcagtcaata tccttcaata
    15241 atcattcgac aaccacaaaa taagtctaaa taatactttt accttattcc tgtctataat
    15301 gtacaaatat atttcatttt taattcatta cataaaaaaa aagaccctct attaatacag
    15361 tcatttaaat catttcgatt aattctttaa tctttttata tacctcttta taattcatac
    15421 ctttatctat caacctaggt aatttcatag atataactct ttcaagtact tgtattaata
    15481 aaaaaactct tgtatttcat ctgtaaaatc ttttctgacc ttttaccttc tgttcttata
    15541 tccagccatt cttgatcttt ttctgtggca atatagtaac catgtattct aatttgttta
    15601 agtgcttttg taacccactt cgtaaatagt tttgcttctg ctttattact tctaaatgac
    15661 atattgtaca cagcttcttc tgtaacaaaa gtagtaccaa agttaggcaa tttatcttta
    15721 aagtttctag tgtaggaatc tccgacagta gactcattaa atttcttttt atattctcta
    15781 tctatatttc ttaatgtatc acgaatattt actatgccta gttcctctcc tacgtcattt
    15841 gcattaaacc aaacttcttc tccatttttt gaccatatca tccttacatt tttctcttgt
    15901 aaaattttca acatactact acctcctaaa ttagttatta ataaagaata ttcaatttga
    15961 acacccttat tttcgaccct tcaatatgag agattaaaat tgtataaaaa aagacctaga
    16021 aatcactcta agtcatgaat tactcattta tcattctcct tatttacaaa ataaaaaaga
    16081 ctaagttggg gtaacttagc ctttttcaag ggggaatata ttatacactt gtttcatact
    16141 accattataa caggggttaa atatcattaa aatatcatct ttttatcatg tatttatcaa
    16201 acagttaatt tcaagccatc tataccaaat aaatacactc caagttcttt taccatttca
    16261 ttaatccaac gtcttgatgt aactactcca caatttaata tctctgctat ttcttcatat
    16321 gttttttcat cacaatagta aagctctaaa gctctatact tttcataaga atgtaaacgc
    16381 tcttgtctta atttcaaagt tttcattgct gaatctatat gtgctatcat aataatagtt
    16441 cttgctttac ttttctttat acttaaaata tacaactctt cattatcaag cttacctaaa
    16501 tcatcctcta agtaatctac atctttagct tcacttaccg ctgagtctat atgtctctta
    16561 aaatcattat aatgcttcat caataatcta gtattatata aaacgccttt tttcctatct
    16621 tctctttctt cttttcttaa ctctcttaca atttctttta tactttcttt atccacttaa
    16681 atcactcctt cttgctctct tcgaacaact tctactgcaa tactcaactt tagatttatc
    16741 caacttataa aatcttctac cacaccaagc acatcttact attttacctg ggcttataag
    16801 ttccatcttt tctttttact ttcatacctt cactccctat attcttttaa ttttgctttt
    16861 actgcttcaa gtaatgcact ttgcccttta tccttattct ctatagcttc cattacttgt
    16921 tcatctattg tacctttaca gattagatga tggataataa cagtttccct ttgaccctgt
    16981 ctataaagcc ttgcattagc ttgttgatac agttctaagc tccaagttaa tccaaaccaa
    17041 acaattatac ttccacctga ttgtaaatta agtccatgtc ctgtacttgc tggatgacaa
    17101 agtaataatt gtattcttcc attattccaa tcatatatat cttttgagtt ttctattgtt
    17161 cttggtttca aactcttaaa ctctttcatt aaacgattat aatcatgttt atagttataa
    17221 aaaactataa taggcttacc atttgaaaca tctataattt cttttaaagc ttctaatttt
    17281 tctctatgga gttcctttac atttttatca ttatcataaa ttgctccatt agctaattgt
    17341 aaaagtttat ttgctgctac agctgctgat gaagctgtta ttatatctct atctaattct
    17401 aatatcttct ctttttctaa ttctttgtaa tatttaagta ttttactatc aaggtgtatt
    17461 tcaattttat tatctatttt tctaggcata ttcaaataat cttctgcttt taagcttata
    17521 caaatatctt ttattttatt atgtattgca ttttctgctc catttttagg ttgccaatta
    17581 tatatagctc ctgtttgata atttttttgt cctggctcaa agtatcgttc tttatatcct
    17641 gtaatagttt tacctagtct ttcacctcta tcaagtaagt acatctgtgc ccataagtct
    17701 attaaactat ttggtgttgg tgtaccagta agcccaacta ctcttttagt taaaggcaat
    17761 actttcttta aacttttaaa tcgttgtgct ttatttgatt taaaagaact aagttcatct
    17821 atcacaacca tatcaaatgg ccattttctt ttataaaaat ccactatcca gggtaccatt
    17881 tctctattta ttatataaat atctgagtct gtacttaaag ctctcactct atctaattta
    17941 ctaccaagaa ctttagatac ttttagatgc tttagatgtt cccatttttt tacttcacta
    18001 ctccaggtat ctcttgcaac tcttaaaggt gctataacta aaacttttga tatatcaaag
    18061 taatcataca ttaattcact tatagctgtt agagtacaga ctgttttacc taatcccata
    18121 tctaatagta aacctatatt attattatct atagtttttc taattgtgta ttcttggtat
    18181 ggatgtggtt taaattccat cccttaacct ccttgataaa atcatctatc tcttttaatg
    18241 tgcttacaca cttaacttta aatcctaatt ctcttaattc tcgcatttta tattgttgaa
    18301 gcttccttag ttttttacct ggtgctttaa gttctacaaa tataacatgt ccttctggta
    18361 ataagacaat cctatctggc acacctgcct cacctggtga aataaacttc atagcctttc
    18421 cacctaacaa ctcaatctct tttttaagtc ttttttctat ttttgattct aacaaaatat
    18481 cacttcctta aaatttaagt gtcaacaatg tcaacagatt ttctatatat atgtatatat
    18541 acatattagg catacatatg tatatacgta tatgcctaat attacttata ctactttata
    18601 cttaattttt gttgacattg ttgacattaa tacctcaaac attgtaatta ctgcatctta
    18661 ggtgtcaaca taagcgtcaa caaagccatt ttttttgttg acattgttga cacttttaaa
    18721 attttcaaat ttactctgtt tttaattctg ttgacactaa cttttacgta cataagctct
    18781 ctgcctacca tatattttcc caaaccttaa atttccatta tatgatatcc aatcatctaa
    18841 tccttttaat atatcattaa tttctcttga taagataggc gtgagttgtt taggttctcc
    18901 attaaatagc tcaacccata tctccataac acacgttttt tctcttaata ttgttccttc
    18961 ttttaaatca ccaaaatctg aaccatgaat atattctctc ttttctgaaa tacttaaatc
    19021 ataccaattc tcagtaatag gtttatttag atactcttcg ataattccag atttagcatt
    19081 ttcttctgag tgagttcttt gttgtctttc agcttctttt ttctcctcat ctgatagata
    19141 tagctgttca ttggctttac ataattctac tgcttctgcc caaatttgat ttctttcatt
    19201 atcaagttga ccattaaata tactcttgtt aaccttcttt actcctgtat ctattggcca
    19261 aaaccttcta ttcccggtct tatctcttaa aaattcttta tcattagttg ttcctataac
    19321 tacacattga cgtaaaaacc ttgatgttct cttcccatat gcgaccctat atatatcctc
    19381 tgatttgctt agaaaatgct taactgcctc aatatctgct tttttagtag ccatcatttc
    19441 acccatttcc agcaaccata ctccttgtaa ttgttcatac gcttctttac cttgtacagt
    19501 agttaaacta tcagaatacc agtctccacc aagtttttta ataaaagtac tttttcccat
    19561 tccttgagga ccagataaaa ccatcatatt atcaaacttt attcctggat taaatactct
    19621 tgctactgct gctactaaaa cttttcttat tatagtcctt gtatagtggt tatcttctgc
    19681 acctaaatag tcaattaaaa gtgtatccac tctcttaatg ccatcccact ttaaagaatt
    19741 taaataatct tttataggat gaaaagtatt attttcaaaa gcaattatta gagcatcatt
    19801 tacttttgat ggtgatgaga tattgtaaat tgtttctata tgatgtctaa gcccagaatc
    19861 atcactatca ttccaatcat ttaatttatc atcttttctc caaggtaact tacctaaaac
    19921 gacagctcta tttgaaaatt cattataagc tatttttcct ttcaaatatg ggtcattttc
    19981 tataaacatt aagatattgt ttgttgtttt cttataactt cccttattgt cataatctaa
    20041 cctagttaac cattcatcat cttcaaaatc tatatcacca aaatcatcct tagctttatc
    20101 aaggttttct cttcctatag tctttcgtac tttagtgtca ctgcttgcaa attcgctcat
    20161 tcgagtaaat gaaggtaatc tatttacagg cgtttcgggt ttagcatctt catcaagttc
    20221 accaaattta tgtatcctaa ctaaatcaaa agcattgcat aaaattccgc ttgctgggtc
    20281 tgtaccatga tgactatatg aaaacttgtc atcataaata actactccac cacttgtact
    20341 accttctgaa tatgtatacc tggtttcatc aataccagga atatatactt catttaagaa
    20401 attttctata gtttctttta tactatagga cctgcaaaat gcacctataa ttccagcctt
    20461 ttcaataggg tcttgttgtt tttttaattg tgtattaaac ttttgcctct ccctcgaact
    20521 ttctggccaa tagcttacat ctgtccagtc taaatataaa tctagtattt catttgggtt
    20581 taaaaactct ccatcttgaa atttaaatat atagtctcca tcaattgaag tacttggaaa
    20641 atacataagt ctatgaggtt gatatgtagt atcatcaaac atatctattc ctatagtatc
    20701 tgctatcatc ctggaaattg cttgatattc ttctggtagt actggtctag ttaaaggtat
    20761 tacaagtcta tatctgggat tattctcagt atgtgagtgc gtagaataca taagacaagc
    20821 ataatcattt aataatgtta tatcctccca tatatcttta ttcgcataat ctatatctaa
    20881 agttataata cttctatttg caatattctc tgcttttcgt cttccatttt ttaagcttcc
    20941 acctacaaat ccaccaacat ctttaactct atctttttca gtctttgaca tcttcctata
    21001 ttctgtatat gtttcttgag ttcttaatgt tttacttaat ctatttacaa gttcggacca
    21061 taaaatactt ttatttttcc aatgtgtttc taatttattt tttcctatgg ccagcatgag
    21121 ttggccatca tgtcttacat ttatgtgttc aatttcactg gcctttatat ccataaatca
    21181 atcacctagt ctttcttata ataatcacat tcatatccat ctgctttaag aggaagacct
    21241 ttagcccaag atatttcttt tcccataata ctgttaactt cttctaaaga acctcctttt
    21301 ttatctacat caattacaag ctcatcatgt acatgcatta caatgctata acctgcatct
    21361 gtcacattaa acatagcctc tcttaagcaa tctctagctg tagcttgaac aatattctca
    21421 actaacttag gtccataagt atctattctt ttccattgtt tacttgtctg ttccatacct
    21481 tcatatgtta tcttatcccc actaaatgta gtatgaggct ctatcttagg tcttagatat
    21541 gataatcttc taccacttgg tagttctata aataaaactc ctggattata aataaattta
    21601 atcccatgtt ggagttttac tatagtccta tcttttatgg cttttttagc tgccttatct
    21661 acatcccacc aaaatttagt tatatttgga ttagcatttc tccatgttgt tacaagaggt
    21721 tgaagctcct cttcatcaag acccattttt atagccccca ttgatgttaa agctcctatg
    21781 cttcccccat atccaagagc tagctctgaa atcttacctt tttgtctaag tgggtcacct
    21841 tttttaatac tttctattgg aactttaaac atatgactag cactagcttc atatattttc
    21901 ccgtgagaat taaatacatc taatctccac ttctcaccag cgaaccaagc tataacccta
    21961 gcttctattg cactaaaatc tgatactata aatctatgac cttcacttgg tataaaagct
    22021 gtccttatca attgacttaa gacatctggt acactatcat ataaaagctc tattaaatca
    22081 aaatctcctt cttttaatag gtttctagct aggtctaaat cctctatatg attttgtggt
    22141 aaattctgta cttgtactaa tcttcctgcc catctaccag tcctattagc cccataaaac
    22201 tgtagtagac ctcttactct attgtcatta cctttagcta atttcatagc ctcatatttc
    22261 tttatagaag ttttggacat taattttcta agttctaaaa ttctaactac attttcatca
    22321 tcaacttgtt ttaatatttc tggaatactt tcttttgtta ggcttgtaat ctcaaagcca
    22381 actttatcac ttaaccattt ttttaattga gctggactat ttggattatt tagaccagtt
    22441 attttaattg cttcttttgt aagtttttca gtatatcttt tatcacattc tattgcattc
    22501 tctattaact ctgtatcaac tttaatacca gtatcattaa ttctctggtc taaataccat
    22561 aatttaattt ctctttcggt agtcttatac ttactaagtt tgtttcttat ttctctttca
    22621 actacaacat cttgtttaca atattcttta aatttattcc atttttccat atcatgtatt
    22681 ggtaaatttc tagttcttcc cttgttaact tttgtagcct tacaaggttt acagaaatat
    22741 tgtattaatg ctttaccttc tttcattttc tgtttatctt cattaaactt taaagcctta
    22801 gacacactat ctaaacttcc tggaagtcct agtgttaacg cctttatcat tgtacatgac
    22861 cactcatttg gttttaaatt aatatttaaa aatttactta ttgctgttct ttcaaaatta
    22921 gcattaaatg ctgattttat aactttatta tcatttaaag cttctattac ttcttttggt
    22981 aactcttcat catttactaa atcaataact tttacctctt cattatcaaa agcataggca
    23041 aataacagta tctcaaaatt agcagagtct acatatctgt agactccaac tttttttata
    23101 tctaaatcac tatatgtttc tatatcaatt gataaggtcc tcattaactt aagaagtcct
    23161 cttcttcatc ttcatattca aagtcatctg agaaatctgc ttctgcacta gctctagctc
    23221 ctccaagtac ttctccatct gctaactttt gaacattttg taagccacaa cctattcctt
    23281 tatttcctgc actattatat gggaaaaagt ttatactaac tcttccataa caaccactat
    23341 atacctctgt attatctaat atttcattta agtctttatc aactattcct ggcttttgtg
    23401 tactatttgc atttaaaaaa tacattccta catattcctc tgcttcatca gctctttctg
    23461 catctccatc acgaagaggt gtttttaaat tacctggtaa ttttccaccc catttagaag
    23521 ttttaccttg ttctttagct gcatcaatag ccttctttat tcttcctaaa gtcaccttat
    23581 ctgattttgg tattaaaata caaactgaat acttgggctc tgcaccttct accattgctc
    23641 tgcttttaaa gatattgcaa taacttaatc ttacctttcc tgttactacc tttgttgatt
    23701 gtactgaatt actcataatt ttcttcctcc taatattttt atatttggta tattgatttt
    23761 atatttgaag ttatttctcc aaatttatct aaatctctaa cttgcttact aaacaattta
    23821 attcttccac aaataactgt tgaagaaaca tttaataact ctcctatatc agatatcttt
    23881 ttatcttgta aaatccaatc tactatttta tcaatatctt ttaaatatga ctttcttgca
    23941 atttttctta tataatcaac atcatagtta aattgaattt cataaaatcc atgtatatct
    24001 tttaatggtc ttttactatc ttcaaataca cttacatcta aaccttctat agagtttcta
    24061 taatgttttt cgccataacg caaagcttta aacatttcta ttcttatgta agaaacagcc
    24121 actgtagaaa acttgcctct gttactatca taatttaatg ctgctttata taacccaata
    24181 catccttctt gataaaactc ttcatataag tatggatgtt gctctacata agacttaaaa
    24241 aatctattta tactaaaatg tacaagattc aaattatttt caactagttt agttatttct
    24301 tgattactca taaaattata tcccctttta aatcttttta tagctactag gaattaaata
    24361 tttttaatta tcctttgctc ttactgatac aaagcatact ggactaactt ttatatgttc
    24421 tggtatatac actctatcaa gatgattgtc atttacttcg aggaaagttg acatcacttt
    24481 atcctttatt aaactttctc ttttaaaatc catcactata acttttgcat tttcttcagt
    24541 tgagttatat tctgtaatat ttagtctctt taacatatct agtaaattat ctttttcata
    24601 atctaaatct ttttcgatac tcttttttct atcctttaaa tctaaaatta tacttatgct
    24661 ttcatctaat ttatctttta tacctgcatc taatggcatg taatatcccc catttatatt
    24721 tcaaaatctt ttttcgctga atctatacta ttaatttctg accttttatc actttctact
    24781 actaaagtag cttttccaac tggttttata attaaatcac ttagtagttt agcaaaactc
    24841 tttttaccta tagctttctc catatcacta attcctttta aggtccttgg cttataaatt
    24901 ttttcttcat cataatctga atttaataaa accttagcaa cttcttgctc atctacatac
    24961 tttctattac ttctgccttc tacaagctta tatcctggat atttaacacc atgcttttca
    25021 gcttgttcta gtgcataact ttgaacatcc tttaaccaat cttgtatatt cttagcaaaa
    25081 cctaaaatat ctgctatctc atatttatta agagcaaatg tgtcagcaaa atcatatttt
    25141 ctagctagtt taaggttatc ctcagctctt tttctgcaat catttttagc tctacaaaat
    25201 ccacaatgac tgccacttac aaactctcct tcaccattaa aagccatttg agccttcttc
    25261 ttaacattat ctgcccatgt aagtaattta gtaacttcta tttcttcact tgatatgtta
    25321 tcaagtctag gttgaattat tgttgtttta attaaatcaa tatcgtatag catttcaaac
    25381 tgattatatg cccctaaacc atatagtcta agttgaggat tctctatagc tgaaacttct
    25441 aaaccttttc catactttag gtctataact tgaagtatac catcagatat tacaacaacg
    25501 tctcctgttc caaatccttc tggaacccac tcactaaaat cgagtctttc ttctaacatc
    25561 actattacat catcacatat agctttacta tcatttacta attcaactac attctcaaca
    25621 taagattgta tatagtcctc catttcagag ttataatact cacttttctg tatcttttta
    25681 attcttgcat tatatgcctt tttacttatt ttttcatact ctagcattaa tttaacttct
    25741 gctaattcat gtgcaactgt tccttcttct gcatatatac tagttaatgg tggatagttt
    25801 tcttctaatt ttatactagg agtgcagtga agccatctat gggctccact cgcactaagt
    25861 cttgcatgtt gtaatggcat ttatgtaccc cctataaact ttctaatttg ttcataaaag
    25921 ctgaataatc ttcttctttt acttcactta acttactagc tccaaattca ccaaataact
    25981 ccttaagctt atccttctta cctgccttac ttacttgtgc tgccttagtt cttacctctt
    26041 cttttgtgta tttaacttca ctagttgtat tttcattatt cttttctatt tcttcctttg
    26101 cttctgctat ttcttcttta acgtcttctt ttacttctac ctttttaatc ttttcagctt
    26161 ttttaacttc aactttcttc tcttctttca tatctgttat atttataggt tctatctgca
    26221 ttgcttttcc tagattaaga cctcctaaag cattcgccac tactaatagt gcatttgtaa
    26281 attctggtgc ttctacttta acttttacat ttacattaac ttcaaccatt ttaaatatct
    26341 cctttttgtg ttatacttta cttgtgttat attttatttt ttattttttt gtgtgttggt
    26401 tattttacca acactttttt atttaatatt ccaaccgata ttttcttacc agttttaata
    26461 tctttaaata ctatatctgc tataactttt ccatcttttt taagagttac tacattctta
    26521 ttattagtat caagactcag caatttcatc cccccactct actgctttta aaagttcatc
    26581 caaattttta ccttgatttc tttcaataaa atcatcaact tcatatcttg aaatttttct
    26641 accatcacct ctaactagtg attttatcaa acctgtgctt actaacctac gcataaaagc
    26701 tgtatctaac tttaaaattc cccttgcttc ttctactgtt attagataat ttggataacc
    26761 tctttttatt aaaacaacta tatctttagg ctccagtacc tttacctttt gttcaatagt
    26821 ttgactctta actctatctg tctcttgttt acttatctct atttctatta aactttttaa
    26881 actatcacta aattgttttg ctatactctc agaaatatcc atgtgaaaat tctctcccct
    26941 ctttttaatt atttatcttc caactaattc gtctaatgta atatctaaat aatcagctaa
    27001 ttttattaga gtatctatag ttggattaga acttttattt ctcagtaatt tatataaacc
    27061 acttacatct atattcaatt cttttgccaa tttataaggt tttatatctc tttttcttag
    27121 catttgcttt atattgtcgc ctattaacat tgtattcacc tcagttctac atggtataat
    27181 ataaacatgg aataaattcc aaaattttca aaaggatggt gtattatgca gttttcaaac
    27241 aatatatcta aagaattaca agaaagtata agaaagacag tctctgatac ttctaacaca
    27301 gagtattttt actatgctga atttcaatat aaaattattc ttaaatctat agaggaattt
    27361 gaaaaagaac ttgatgatga acatgaaatt gcactaaaat tgactaactt tggaaaagat
    27421 gtcttaatga ttgttgaaga agtaggttat cataaccctt gtctaattca ctactacggc
    27481 atagtaaatg gagtttattc tgaaattctt caacacacat cacagataaa ctttatgata
    27541 acttcagtaa agaaaactga cccttcaaaa cctgctagaa gaataggttt tatattgtaa
    27601 ttatcattct tattttctga ttctttcttt agtaatttca ctaatttttc ttttttcact
    27661 tttattcatc tcatgtaaat acaaaactat acattggtac atataatcta taaaatcact
    27721 atttgattga gctgttatct gactaaataa ctgtgcttgc aattgatttt caagcatggt
    27781 tattcttttc tctatttctt ctattttctt attttccaat tcaatctctc ctttctaaaa
    27841 tattctgtat ttagttttca aagtactaac ctaatattga agtttgataa ctatatcctt
    27901 tttctatatc tggtaatatg ttatttgttt tcaataaatc atataaaaac aatcttccct
    27961 tttgagtcca cttagttgtc atttttacat caggcattcc attacttcta gttatgtcta
    28021 ttgtttctga atgagtgtat cccttccctt gatgttgttt atataaaagc cattgtccac
    28081 tttgtttata ttgaatccct ctttcatgaa gtattttatt catttctttt ccactcattc
    28141 catagtcttt tgctatttga gttattgtga caagtccttt attttttaat atcatatctg
    28201 tataatctgc ctttggtttt agttctttta ttacttggtc tttcatttta ctttctagtt
    28261 gtaactgctc atttacttct acttgctcta taagatgttg taacgcttct ttatatgtag
    28321 ttggtagttt agtttgcaaa tctatcatat tatatgtccc agtactacgt atacttggta
    28381 atatctcatt agttacccaa cgtttaaata attttgcact tggcaactta gaacttaata
    28441 ttaaagaata aagaccactt tcattaatta ctttcatatt ttgattacca ccaggagtcg
    28501 gtatttcacc tactccttta tcttcatcat caacatgtct tttcaaagca tcagatgtat
    28561 ctttatatcc taattgttct gcaatatctt ttccaacaaa ccaaaattct ccatttagtt
    28621 cgattactct tatttctcca aaagtcttat ttttgaatat ttgtaaatta ttcataattt
    28681 ctttcctcct tatgattgtt tttgtgaaca ataaatttta atttatgtta accttttttc
    28741 taaaaaaagt tcatccattg ttttatttaa aatatagcta atcattatca tttctttttc
    28801 cgtaaaattt ctttttccat tttcttttag attatatgtt gattttgcta ttcctatctt
    28861 atatgctagt tcttcttggg tatatcctgc ttctattcga ccagctttta aacttctttt
    28921 cttcatgttc ttcaccttcc aatgttttat ttttgtgaac ttcatacttt tattatattc
    28981 acacaaacaa aacttgtcaa tacataagtt tatttttttg ttaacttttt tatttttttc
    29041 taaacataag tttacgtttc tgtaaactta tagtatcatt taattattgg gaggtgttgt
    29101 ttgtggcaac ttttggagaa cgtttcaaac aattacgaga agagaaaaaa cttactcaag
    29161 atgaactagt ttcaaaattc aataaagttt actttacaag ttttaataaa tcaacaatat
    29221 cgcaatatga aaataataaa agaaaaccag aaataaatat tctagaaaat tgggcagatt
    29281 tttttgatgt atcaattgat tatcttttgg gtagaactct tgttagaaat cacatcgata
    29341 ctgtagccgc acacagagtt aatcctcaca aagatttacc agaggaagct caagaacaac
    29401 tcaacgatta tattgaattt ttaatgaata aatataaaaa ataaggattg aatctatgtt
    29461 aatattaaaa aaattgagaa ctgaaaaagg aatttcttta gataaattaa gcacagactt
    29521 aaatataaat aaatccactt tatccagaat tgaaaatggg ttaagagaac caaaagaatc
    29581 atttattaaa gattgctcag actattttgg agtatctaca gattacttaa ttggaaaaat
    29641 taacatagat gattcaaata aattaacaaa atgcttaaat tcaacttttc caataaggtt
    29701 aaaagaatta agaaagaaaa aagaattaac tcaagcagaa ttatcaaaat tacttaattg
    29761 ttcactaagc aaaattgcta tgttagaaac tagcaaaaga gaacctgtta aagaagactt
    29821 gttaagaatt tcagaatttt ttaatgtgtc agttgattat ctacttggta aaacctcaat
    29881 tgaaaattac ataactactg atgaaatatc caaaataatt aaatcttatg aaagtttacc
    29941 taaagaagcg caagaacata ttaatagcta catagagttt ttagttgata gatataaaaa
    30001 atgaatattt agagcagttc actcctgctc tttatatata aaaaagtaac acatacattc
    30061 tttttatagg gggatttcaa tgaacaaact agacgcactt ttagacttag caaataatga
    30121 agagatagaa atttactaca ctgacaaaat agcagatgac ataaaaggat tgtatataaa
    30181 cagacaagga ctaaaaatta tatcattact taattcatta aaacaaaaca atgctaaact
    30241 aatagaaatc ttagcagaag aattaggaca tcattttacc agtgttggaa actatgtatc
    30301 ttcaaaaaac agttacaaaa ataaaatctt gatagacaaa actgaaaaca aagcactaaa
    30361 atgggcatgt gaatttctta taacagaaga agaaataata catgttatta attcacacgc
    30421 tacaagtgta tacgaaatag ctgaagaatt acaagttagc atcaacttct tactaaaaag
    30481 attagaattt ctatcaaaaa agaaaagcat gttggactta ggaaataata gatttttagt
    30541 attaactaat ttgccaaatt tctacatata tgaggatatt ttttaaactc atttattcta
    30601 cttttataga ttttttactt aataaatata tatttcaata ttattataat aaactacaca
    30661 taaaagctaa aaaattgtaa gaatattaag aaaataatta agtaaaaacc agataaacaa
    30721 aattaagata atattgtaca taacaaaagt atataaagag cagttaatct gctcttttat
    30781 ataaacacca aacatacata cattctaaaa gggagagata ctattatgaa aggtggagta
    30841 agaaaaagaa gcaacaaatg gtattactac tttgacctag gcatagtatc tgaataaagc
    30901 aatatcagct taccttttgg tacaaaaaat atttcttact taacaacact caaaaaaatt
    30961 accaaataaa tatagaaaac taaaattaag tatttataaa gtaaaaccat tatacacagt
    31021 agtaattttg atgagtaaac acatattcca tatgtaataa agcttgaagt taaaagtgga
    31081 ataaataaaa tctagaaaaa atttttattt taagttaagc ttattatgga taataaaatt
    31141 cttgcaaatt tagaatcaaa tgatacaata agaatataaa atacttgttt gagaggatta
    31201 ttttcgtgat taaaaatttt gatgaatgga aagagtatga tggtttttct tatggtagtg
    31261 gaagaagcga gaaaatctgg ctaattaatg aaaaaactaa agatataggc ttgtttaaat
    31321 tccctaaaac aaaagaaact ggagaatatt gggcagaaaa attagcctgt gaaatagcta
    31381 gtttgttaaa gattccttgt gctaatgttg agataggtac atataataaa agaattggtt
    31441 caatgagtta tttaatcaat aaaaatgatg agaaattgat tgaaggcgtg tggttaataa
    31501 acaaatatta tccttgttat aatacagata agttatatga ttataaaaat aatgaatact
    31561 attcattgaa aatgattttt aaatctatag aagaatataa cataaaaaat gattttctaa
    31621 aaatgttaat ttttgattac ttgattggaa atagagatag gcatcaaaat aattgggctc
    31681 tactagaaag tcaaaataaa attactctta gtcctctata tgataacgga tcatcattat
    31741 gttgttatgt taatattgag aacatagatt ctttcttcac tgatcatcaa agatttgaag
    31801 ctcttataaa tacacgttca agatcaagaa taaggataga tggaaaaaat aaaaaagaac
    31861 caacacactt agaagtgcta aaatatttaa attcaaatta ttatgaacaa actatagatt
    31921 ttgtagaaaa gataataaat cttatgaatg aagtaaacat aaatacatta atagataact
    31981 attcagaaaa tattataagc ccaaagttaa aaaaattgct aaaaatatat ctaaaagaaa
    32041 aagtgttaag aataaaaaat atatataatt tgtgaaagag ggataaaatg tcaattaaaa
    32101 atggaaaaga ttttttatat gttatttgga aagatccaaa aagtagaaga caatttataa
    32161 ttggaaagtt agctaaaaat ggattgtatg aattttctta tgaatatgaa attgatgaag
    32221 ctattaaagc aggttttaat gctttaatat catttgatga tattagtaaa acatattata
    32281 gtgaagattt atttagccca tttgcaagta gattacctga taaaaaaaga aaggacatca
    32341 ataaaatttt ggataagtat gatatgtctg agtatgatac atatgaactt ttaaaaagaa
    32401 gtggtgcaag attacctata gatacactag aatttgtaga tccaattcct ttggacattg
    32461 ataaaaatat aattagatat ttttatattg caggagtaag acattatgct gggtgtgaag
    32521 gacatgaatg tgataattca atagaattag aatcaaatga agctctagtt ctagagttag
    32581 aaccagaaaa taaatttgat cctcatgcaa tcaaggtatt tgataaaaaa gagaatcata
    32641 taggttacat tcctagatat tatagtggag aattaacaag tataataaat agaggattaa
    32701 agtataattg cattattaaa tttgttaaca aagaaaataa ttgtgatgaa tgtataaaag
    32761 ttaaattaga aatattattt gacgaatata attaatgtct tcttgtaaat ataggagaca
    32821 ttttttatat aaacaccaaa caaacataca ttctaaaagg gagggatact attatgaaag
    32881 gtggagtaag aaaaagaagc aacaaatggt attactactt tgacctaggc atagtagaag
    32941 gaaaaagaaa aaaagtagaa agagttggtg gcaatacaaa aaaagaagca gaaaaagcac
    33001 taagagaagc actaaatgaa tatgaaaact ctggcatagt ctttgaagaa agtaacatca
    33061 gcttatcaga ctacctagac ttttggtaca aagaatatgt tttactcaac tgtaaataca
    33121 acactcaaga aagctaccga ataaacatag aaaaacatat aaagccaaaa ctaggagctt
    33181 acaaagtaaa agctttaact cctgcaatac tacaaaactt cataaataaa aagtacaaag
    33241 aggattattc tcaaaataca ttacaagtat taaaagccat attacatagg tcattaaaat
    33301 cagcagtcca tccttacaaa cacatacgag aaaaccctat gcaatatgta agcataccaa
    33361 aaactaaatc taaaacagaa actaataaag ttaaaactat tacattagaa gaatttaatc
    33421 aaatactaaa tatatttcct caagattcat ttcaacgtat agttttacta attggatttc
    33481 atactggtat gcgaagaggt gaaattattg cactaaaatg ggataatata gaccttgata
    33541 ataaaactat cacagtaaag catactttga ttaaaaaacc aaatggaatg tttgaattag
    33601 ggcaaccaaa aacagaaagc tcttgcagaa ctatatttac aggtgacact ttaataaagg
    33661 cattaaaaga acataaatta tatcaaaaga aaatgaaatt aaaatacgga gaattttact
    33721 ttgatagtga ttgggtatgt accaaagaaa atggtcaaca agtgaatact cacactttag
    33781 acactatagt aagacaaatt cgagtagctt taaacaatga cttccatttt cattctttaa
    33841 gacatgcaca tgctactcta ttattagaaa atggtgctaa cattaaagac atacaaaacc
    33901 gtttgggtca tagccaatta tcaactacaa tggataccta ttcacatgta actgataaaa
    33961 tgaaaaatga aactgtagat atatttgaaa aaattacaaa ttagagtttg ccacccaaaa
    34021 atataatacg gtggcaaatg ggtggcaaaa tctaatttat ctattttaaa agctaaaatt
    34081 atcaaattta tatagtcagc tatacgcttg taatttcaag gctttagagt atataacaac
    34141 cataactaat ataaggtatt aataataaat ctaacgaata aaacttaata tttacttaag
    34201 ttgtaatact attctaaatt gtataattaa aatttaataa gttcttaatt atatattcat
    34261 tgatttattt gcaaaaataa aaaatgccaa tctatctcta aacaaaaact gaataccaat
    34321 aaaaatttaa taaaaaattt tatcaatatt cagtataagt tttagttaca tatcaaattt
    34381 tccaatgcat cattaggtgc tacaatagga taaacatcat aatccttatc tatatcacat
    34441 tgtaaaaata caggtttatt aaaatctatc acatctagaa cctttcctaa ttcttccata
    34501 ttggatacct tatatccatc aatattatat gcatttacga gtttaacata atccacattt
    34561 tcattaatat cagtttgaga gtatctttga ttggaaaata acttctgcca ttgtcttacc
    34621 attcctaatg ttctattatt gagtagtaaa ataagcatag gtacattata atttgcaact
    34681 gtagctagtt cattacagtt cattctaaaa cttccatcac cagttactaa aaccacattt
    34741 ttatctacat taccagcttt agttccaata gctgcaccta aaccaaatcc catagttcct
    34801 aaccctgctg atgttataaa acttttatta cctttaaaat tccagtattt agcagaccac
    34861 atttgatgtt gaccgacatc agttactacc acagtgggtt tctttaatgt ttcatatttt
    34921 tcatttattt ttttaagtat attttgtgga tgaaattcat atgtttgtac accctcactc
    34981 tttctaaatg tctttatctc ttctttccaa ttgctattat tcttactttc aaccctttca
    35041 attaataaac taaggactag ctttacatct ccaaccaaag atacattaga ttctatattt
    35101 ttacttattt cagatgggtc tatgtctatg tgtattattt ttgcattttt agcaaattca
    35161 gaacttttac ttatcactct atcactaaat ctcgcaccta tcgctattac taaatctgaa
    35221 ttagaaagtg ctaaattact ttctctactt ccatgcattc caaccattcc aagagatagt
    35281 tcattctttc tatctatatt tccaagcccc ataagtgtat ttagtacggg tgtatctatc
    35341 ttagttgcaa atttttcaag aatttcctca ctgtctgaag atttaacacc tccacctgca
    35401 tatattacag gctttttaga ttcttttatg atatctattg cttcatttaa aagcttaata
    35461 ttagtttcat catctagatc aaaatcactc ttataatcca tataatcatc tatttgacat
    35521 aaatcatagt cctcaccact aaaatccatt tctgctaaaa ataaatcttt tggaacatct
    35581 acaagtacag gtccttttct acctgaattt gcaactctaa aagcttcttt tattgtagga
    35641 actaattctt tagtgtttct aactaaataa ttatgttttg tcatagataa tgttgctcca
    35701 gttatgtcaa tttcttgaaa agaatctttt cctaataaac tagttggcac ctgccctgaa
    35761 attacaacca taggtgaaga atccataaaa gctgttgcta ttccagttat ggcatttgtt
    35821 gctcctggac cagatgttgt aaaacaaact cctactgtat tagtacttct tgcgtaccca
    35881 tctgcagcat gaactaaacc ttgttcatgg gatgtcctta tatgtttaaa atcatctgaa
    35941 taatcgtata gagcatcata aagaggtatc acggctccac caggatatcc aaatattgtg
    36001 tcaattccct ctttctttaa acattctaaa attacctttg ctccattcat acgcactact
    36061 atacaccact ctttccctca aactaatcca tttaatatat atttatttta agaatgacat
    36121 catacttctt agatttctac caacttcggc aatttctgta ttatattctt cttctctagt
    36181 ttttaggaag ttttcacgtc cttcttcatt ttctttaatc cacgcttttg caaattttcc
    36241 attttgtata tcctctaaaa cattttgcat accttgtttt gcagcatcag ttattaccct
    36301 tttaccagat acataatctc catattctgc tgtgtcactt atactatatc tcattctttc
    36361 aaatccacct tcatatataa ggtcgactat tagtttcatt tcatgtaaac attcaaagta
    36421 tgctacttct ttttgataac ctgcatctac aagcgtttta tatcccaatt ttataagttc
    36481 acttattcca ccacaaagta ctgattgttc tccaaataaa tctgtttctg tttcttcttt
    36541 aaaagtagtt tctaaaacac ctgctcttgt tgctcctatc ccttttgcat atgctaaaac
    36601 tgtctctgta gcttttttag tgtagtcttg atatactgca aatagtgcag gaactccact
    36661 tccctttgta aatacatttc taactaagtg accaggtcct ttaggagcta ccattacaac
    36721 atcaacaaat tctggtggtt gtacttgatt ataatgtata ttgaatccat gagcaaaagc
    36781 taatgtctga ccttctttta agttatcctt tacactctct tcataaactt tcttttgttt
    36841 ttcatcaggc attaacatca ttgtcaaatc actttctttt gtagcttctg ctacactctt
    36901 aacttcaaat ccatcttctt ttgctttttg tgctgattta cttccgtcat aaagacctat
    36961 cactacatgt acaccgttat ctctaagatt ttgtgcatgt gcatgtcctt gacttccata
    37021 acctaaaact gcaacctttt tattttttaa aacctctaaa tccacatctt tttcataata
    37081 cattcttgcc attttcattt cctcccaata ctttttctta tttttatgat atttattttt
    37141 attagaaatt catactcatt atcattgttt taatattatt caacagattt aaattctaaa
    37201 tttatataat cttacaatta taattttaga attttcagtt tttattagct acaacaaact
    37261 aataaattta ttaactgtga taaactgata aattcaatga cacttatatt ttaatctaag
    37321 atttttctta tttaatattt atctttagct ttataaaata tatttaatta atgtctcatt
    37381 ctttcaacag ttatctctct tatatcatgt agttttttca tatggtttaa gacagaatct
    37441 aaagatgtct tttcttcatt tactattaat tttatacctg aattattcat attatctaca
    37501 gtcatactta ttgattgtat atcaacctct cttcttctta gagtcatagc cactcttaaa
    37561 aaagaatcta ttccttggtt taatttagca tatacagtat tttccataaa aatccctcct
    37621 tatttttatt atttttttat taattttata tggattaaat ttatttatat cgcttaaaat
    37681 aaaaaaactt tcatctttat aagcaatata aatattactt ataaggacga aagttatatt
    37741 ccgcggtacc accttatttg tagatataaa aaatacatct acccctcttt tttcaggtcg
    37801 ggtaattaat taccttaacc ttagtcatgt aacgttgaca tacgtttgta cttactaaaa
    37861 atattcagta caaaagctcc agagtgatca ttatactact gttaacacca attctcagca
    37921 acattggttc tctgtggata acactattag tattgttgtc tctgtcattg cttttaattt
    37981 tttaatttta tattttaatt ctgttttgtt gttaatatag attatattcc ctatcattta
    38041 caatgtcaat gacttttttt aaaattttca gattatttat ttttttcaca ataatacttc
    38101 ttttatactt tacgcctgta ttttggaata atcgttttca gattattatt ttatatccat
    38161 ttatttttag ccaattttct ttatctttat aatcgggcat aatggatttt actaaatcat
    38221 agaatttttt agagtgattc atatgtacta aatggctaaa ctcatgtatt attacataat
    38281 caattacatc taatcttgcc atagatattt ttgagtttat ataaatattt ttttgagctg
    38341 tacaacttcc ccatctctta ttttgttctt ttaccttaac acttgctgga actaattgct
    38401 tcattatttc acaatttaat ttaagaaaat ctattctctc taatactgtt ctttcacttt
    38461 ccatcttata ccaagatttt aaagattttt taataaaatc tgtacttgta tcatttgtct
    38521 gaacaactat ttgatattcg ttaatagtta ttctacagtt actttttttg acagaatctt
    38581 tcaacagttc ttttataact agatggtact cttcacctaa ataaagaaat ttttcgccag
    38641 ttataaacat tctttgtttg tatacttctt ctcttccttt atatttttct gactttttaa
    38701 gtatccagtc tcctttttca ataattatat cttttattat ttttttggat attttaggag
    38761 gactcattac aattattttg ccaaatggat ctatttttat agaaatattt tttctatttt
    38821 tatatactaa aactgctttt atttcaatcc ctctaaaatt aacatttaaa gtatcaatat
    38881 ctttactccc tgtgttcatt agtttatttt tccttattag ctctacaatt tataagttca
    38941 gcagctatac atacagctat ttcagctggt gtttgagcat tcaattttat gcctattggt
    39001 gcatgtactt ttgataattc ttccttctta aaaccttttt tcatgagttt ttcgtacgtc
    39061 aatccaattt ttgttctact tccaatcata cctatataac cagtttctct tttaagagcc
    39121 cattctaaag cacttgaatc atatagatga cctcttgtta aaataattat atagctattt
    39181 tcgtcagttg gaaaatctgg tatattttca aaagaatcta aaactactac ttctgattct
    39241 gggaaccttt cataattagc aaattcttct ctatcatcta ttactactgt tctaaattct
    39301 aaaagagata gtatcacagc aacatctctt gaaatatgac ctgcaccaaa tatatatgct
    39361 ttacttgtat tttcctttag tctcttattg aatttttcta tattactttt taatttacta
    39421 tctataaaat ctatttgtat ttctccagta cctccacata tcattcctag ttttgccaca
    39481 tcagatttgt ttagagtaaa tttatacaac attgattctc tattttttat aacattaatt
    39541 gcatgtttta tacattctgc ttctacacta cctcctccta ctgaaccaaa tatagtagaa
    39601 tcatttttca caatcatcat tgctccagtt tcacgtggtg ttgaacctga atgagacgtt
    39661 attgtagcaa atgcgaaatc ttcattattt tctattaatc ttattgcttg ttcatatata
    39721 ttcatataat tctccttacc agtctatcta aaaatcttct atatatctat cttagtcttt
    39781 ttattacttt atttggtatc acaaattcta ctgctcccat ataaccaggt actacttcat
    39841 attcttcaaa actaatcaca agatttccat ttttattaaa ataaaaatct tgatacttat
    39901 ttatagattc aaaatctttc actgggaagt ctttatcttg gtctataaaa taagattttg
    39961 tatcatcttt cttaatttga tttctcatct gctcttttat attatcactt atagctctaa
    40021 tatatctact atctttaaaa aatattggta aatttaatag tattcctcta tttttatcaa
    40081 cagtgtaatg cttcttagtt atagacgagg aatcttctat ctcttctttt gtcatttcta
    40141 ttgataaaaa gtccttagaa ttatttttga cattatggat tacatttagg tatctatgac
    40201 ccttattatt ttcctttttc attttatttt gaaattcact gtaaattttt ttcccatctt
    40261 gcaaaaactc attgtttaat ttattctcta aagttttatc ttttaaacct tttattttag
    40321 gaatactcac attcacttca taattgcctt gtttaaagtt gagactctta gcatttaaca
    40381 cctttatcgt atcactattt gaagtctcat tagaggaact acctgcaaat atagggttta
    40441 tatctactaa tgagactaat aagcatattg aaaatataga aattttaaat atagattttt
    40501 taagcttttt atatgtagtc atattgtcct tcttaaaata tgtatatata aactactatt
    40561 caatttacaa atcttttatt actttatatg gtattacaaa ctcaactgca cccatataac
    40621 caggtgctac ttcatattca tcaaaacaaa ttacaaggtc ttcattttta ttaaaataaa
    40681 aatcctgata cttattaatt gttttaaaat cttcaacagg caagtctttt ttttgatcta
    40741 taaaatagga ttttgtacta tcctttttca tttgttctct catttgttct tttatattat
    40801 cacttataac ttttatatac ttatcatctt taaaaagcat tggcaaagtc aaaactattt
    40861 gtcttttttt atcaatagta taatgtgcct tactcacata tgatgaagcc tctatctcat
    40921 tttttgtcat ctctattgat agaaattttt tagaattatt ttttacacta taactcaaac
    40981 ttaaagattt atatccttta ttctttgatg attgtatctt ctccattctc tcttggaatt
    41041 gatgataaag cctttttcca tcttccataa aactactgtt taatctttgt tctaagtttt
    41101 tatcttttaa acctcgtatt ttaggaatat caatctcagc ttcataattt tcacttttta
    41161 aactataatt ttttatagtt attacttcta ctattactcc aattacaggt atcttagaaa
    41221 aattgtctgc aaatacagga cttatattta ctaatactgt aaatatacat gcaaaggcta
    41281 ttgcaacttt aaatcttaat ctatttactt ttttattttt ctctcgatat atgttttcta
    41341 ttttttcatg atttattata gtatctaatt tcttgggtat tggaatttta tgatactcat
    41401 cttttaactt atttaacctt tctttgcttg tcattctttt tatccctact cttcaatttt
    41461 taattttagt ttttttaaag cagtatataa cctagtttta acagtattca cattttcatc
    41521 caatattatt gctacttctt caatctttaa atcttcaaaa aatcttaata ttataataga
    41581 tttgtattca ataggtaatt cttccaaagc tcttcttaaa tccaaatcag tatatttatc
    41641 atactctcca gtctcatcta taaggtcaat atctgtcata ttattatatt tacggttttt
    41701 tctaataaaa tctatactcg ttctaactaa aattttataa aaccatgtct ttatataatt
    41761 tacttcttta atattttcca ctgagtatag tgccttatac atggcttctt gaaccacatc
    41821 taaggcatct tcttcattct tcgtataact atatgctatt ctataaaaag agtctttatt
    41881 atcgataatg tatttctcaa ctttcgttct ctttaaactc ttaaacattc ctgtaaaatc
    41941 tccctccgat tacaggctag gattgagctg ttagaaattc tatctgtcta ttttagcatc
    42001 ttcattcagt ttttttatat gctcaatata cttttcattt aaaatagatt ctcttattaa
    42061 actctgacac tcattaaaac ttttttgtct ttctctttta tcagtaactt tgactatatg
    42121 atatccataa ctagtttcaa acacatttga aacttcattt ttctttaatt tgaacacttc
    42181 ctttgtaaac tcagcatttt tatcatcctt tgtaaaatat cctagctgtc ctccattttt
    42241 tccagttgct ttatcatccg aatatttttt agctaaactt tcaaaacttt ctccattttt
    42301 gattttagtc aatatattat ctgccttctt cttcaaagct tcttttttat ctttgcttac
    42361 ttctttttta tttttatcta aagtcgatat aagtatctga gaagcactta cttcttctac
    42421 attaaaatct tttttatgac ttgtatagta ggcttccata tcattatcac ttatgtttat
    42481 tctatcttca aaggcctttt tatttttatc tattgctaaa tctctagata tttcttgttt
    42541 taaatattct ttatcaacac ctgctttgtc cattttttcc ttatagcttg tattcaaatt
    42601 catcttatct tctagttctt gatattttga gtctacttca cttttacttg gagttagtcc
    42661 tttatcctta gcctcttgat ataaaagttc attatccacc ataaacgata ttataacatt
    42721 ttctaattta tttctacctt ttttatccaa agttttttct aattcatcta aagactgccc
    42781 atttatataa ttattagtag cagataaaac tgcttttgtt tttttgtact gttcttttgt
    42841 gatttccaca tcatttactt ttgctaaact tttattacaa ccaaccatca tcaaagacaa
    42901 tattccgacc attcctatat aaagtttttt attcaatata cctacacctc actcattttt
    42961 attctcaatt tctaaaaata tcaatcaata ttcttatatt ttaactactc taaattacgt
    43021 aaccaataat tttttggtat ttggttttga tctactggcg caaattcata accttcatct
    43081 gataagaatt ttaaaactga atctaaagct tctgcactct gttttttctc atgcattaaa
    43141 actacaagtt ggtctttatc ttcacctttt ctattcttaa tatgattttt tacattttgt
    43201 acaatttgag aagaattaga tctccaatct tctgtatcta agtcccagtc ccaaatttta
    43261 tatccagcat caactaaagc ctgataagag gcttgtggtg tatatggttt gcttccataa
    43321 ggtattctta ttacttttga atgtttacca gttatcttat aaaaagtttg atcatttgta
    43381 tcaaattcct cttttgctga tgtactagta acataaagct tgtgaatatc atgtgataca
    43441 ctatgaaaac ctgctgtgtt cccattttta attatatttt taacttgctg tggatattcc
    43501 ttcatattcc catctatcat aaaaaaagtt gctttaacat tgtatttatt taaagttttt
    43561 atcatctcgt cagtaaattt agatgggcca tcatctatag ttatgtatgc tatttttcca
    43621 gaacttttac ttggcccttt actaacttct attgatgtat tagatactat atctgtaata
    43681 gtagaacttg acagttttgc atttctacta atttcatttt ccttcatatt taaagagctg
    43741 acgcgaacac caactactat aaaagccaga cacactacaa tagcacttaa aagcaaatac
    43801 aacttctttc tatttatttt tttcttttta tttctcatcg ttcgacctcc aatattacta
    43861 tatttttaca tttatatttt tgtagtattt tatcccaaaa atttacacta catatatata
    43921 gacgttgaac ttcgacaaaa agttttgctt aatttttaaa atttgttatt tcggtgatta
    43981 ttatgctgta taatttctgt ataattgtat agaatgttga aaattgagta ttatatagtg
    44041 ttttttacaa ttaattctag ttaaaatgtc atttataatt tt
//
LOCUS       DAEQJM010000028        42216 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.028, whole genome shotgun sequence.
ACCESSION   DAEQJM010000028 DAEQJM010000000
VERSION     DAEQJM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42216
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.028"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            76..1932
                     /locus_tag="KRQ43_001896"
     CDS             76..1932
                     /locus_tag="KRQ43_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH2742252.1"
                     /translation="MDIHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYRGGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIIDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALINKIFESDKGVVENKKVVTFELNVSINDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSENNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    2015..2255
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    2321..2556
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2641..3858
                     /locus_tag="KRQ43_001897"
     CDS             2641..3858
                     /locus_tag="KRQ43_001897"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH2742253.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRSIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            3972..4466
                     /gene="cdeM"
                     /locus_tag="KRQ43_001898"
     CDS             3972..4466
                     /gene="cdeM"
                     /locus_tag="KRQ43_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HBH2742254.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGCSDSGGNRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     EAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            4731..5996
                     /gene="hisD"
                     /locus_tag="KRQ43_001899"
     CDS             4731..5996
                     /gene="hisD"
                     /locus_tag="KRQ43_001899"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBH2742255.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(6199..6951)
                     /locus_tag="KRQ43_001900"
     CDS             complement(6199..6951)
                     /locus_tag="KRQ43_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2742256.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANKKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(7069..7338)
                     /locus_tag="KRQ43_001901"
     CDS             complement(7069..7338)
                     /locus_tag="KRQ43_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742257.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            7813..8907
                     /locus_tag="KRQ43_001902"
     CDS             7813..8907
                     /locus_tag="KRQ43_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH2742258.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LRERSINGVISMCLKETDYQYSLSNKKGGY"
     gene            8909..9859
                     /locus_tag="KRQ43_001903"
     CDS             8909..9859
                     /locus_tag="KRQ43_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBH2742259.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGLKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINNNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKIDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            9852..11036
                     /locus_tag="KRQ43_001904"
     CDS             9852..11036
                     /locus_tag="KRQ43_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742260.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKKSLMREMNNVSKGVIDNEDTPSGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKSLLEISSYFKSKGLKIGIDTFSPFISYFTGQDLKKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIIAPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            11049..12545
                     /locus_tag="KRQ43_001905"
     CDS             11049..12545
                     /locus_tag="KRQ43_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH2742261.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNSHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHTVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSEGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            12568..13518
                     /locus_tag="KRQ43_001906"
     CDS             12568..13518
                     /locus_tag="KRQ43_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742262.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLVSFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            13539..14501
                     /locus_tag="KRQ43_001907"
     CDS             13539..14501
                     /locus_tag="KRQ43_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH2742263.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            14873..15505
                     /locus_tag="KRQ43_001908"
     CDS             14873..15505
                     /locus_tag="KRQ43_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH2742264.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            15916..16008
                     /gene="kdpF"
                     /locus_tag="KRQ43_001909"
     CDS             15916..16008
                     /gene="kdpF"
                     /locus_tag="KRQ43_001909"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBH2742265.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            16049..17731
                     /gene="kdpA"
                     /locus_tag="KRQ43_001910"
     CDS             16049..17731
                     /gene="kdpA"
                     /locus_tag="KRQ43_001910"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBH2742266.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            17756..19813
                     /gene="kdpB"
                     /locus_tag="KRQ43_001911"
     CDS             17756..19813
                     /gene="kdpB"
                     /locus_tag="KRQ43_001911"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBH2742267.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNVGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMIL
                     NLG"
     gene            19832..20458
                     /locus_tag="KRQ43_001912"
     CDS             19832..20458
                     /locus_tag="KRQ43_001912"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBH2742268.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNASYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNIEVAKILGLI"
     gene            20695..21603
                     /gene="cysK"
                     /locus_tag="KRQ43_001913"
     CDS             20695..21603
                     /gene="cysK"
                     /locus_tag="KRQ43_001913"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBH2742269.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            21630..22220
                     /gene="cysE"
                     /locus_tag="KRQ43_001914"
     CDS             21630..22220
                     /gene="cysE"
                     /locus_tag="KRQ43_001914"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBH2742270.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            22380..22568
                     /locus_tag="KRQ43_001915"
     CDS             22380..22568
                     /locus_tag="KRQ43_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH2742271.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(22622..23491)
                     /locus_tag="KRQ43_001916"
     CDS             complement(22622..23491)
                     /locus_tag="KRQ43_001916"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HBH2742272.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDMNKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(23688..24932)
                     /locus_tag="KRQ43_001917"
     CDS             complement(23688..24932)
                     /locus_tag="KRQ43_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742273.1"
                     /translation="MENNLNIAKKNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYYMENNTNITIYENNTLQYKFDEESEDIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKSRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            25223..25534
                     /locus_tag="KRQ43_001918"
     CDS             25223..25534
                     /locus_tag="KRQ43_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH2742274.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      25627..25719
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            25819..26613
                     /gene="thiD"
                     /locus_tag="KRQ43_001919"
     CDS             25819..26613
                     /gene="thiD"
                     /locus_tag="KRQ43_001919"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBH2742275.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            26637..27425
                     /gene="thiM"
                     /locus_tag="KRQ43_001920"
     CDS             26637..27425
                     /gene="thiM"
                     /locus_tag="KRQ43_001920"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBH2742276.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGIYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            27448..28080
                     /gene="thiE"
                     /locus_tag="KRQ43_001921"
     CDS             27448..28080
                     /gene="thiE"
                     /locus_tag="KRQ43_001921"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH2742277.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITERYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEATCAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            28219..28521
                     /locus_tag="KRQ43_001922"
     CDS             28219..28521
                     /locus_tag="KRQ43_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742278.1"
                     /translation="MIKILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRVPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(28587..29336)
                     /locus_tag="KRQ43_001923"
     CDS             complement(28587..29336)
                     /locus_tag="KRQ43_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742279.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(29330..30292)
                     /locus_tag="KRQ43_001924"
     CDS             complement(29330..30292)
                     /locus_tag="KRQ43_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742280.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVKMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(30296..30754)
                     /locus_tag="KRQ43_001925"
     CDS             complement(30296..30754)
                     /locus_tag="KRQ43_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH2742281.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            31110..31466
                     /locus_tag="KRQ43_001926"
     CDS             31110..31466
                     /locus_tag="KRQ43_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2742282.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            31538..32254
                     /locus_tag="KRQ43_001927"
     CDS             31538..32254
                     /locus_tag="KRQ43_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742283.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            32247..33071
                     /locus_tag="KRQ43_001928"
     CDS             32247..33071
                     /locus_tag="KRQ43_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742284.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQNILFFGMLGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIVLITMIYGFLISQTATLFICKYIFNFIFRNIPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIINLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            33083..34282
                     /locus_tag="KRQ43_001929"
     CDS             33083..34282
                     /locus_tag="KRQ43_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742285.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYANILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQDIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            34291..35103
                     /locus_tag="KRQ43_001930"
     CDS             34291..35103
                     /locus_tag="KRQ43_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742286.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFIFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVLEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            35114..36382
                     /locus_tag="KRQ43_001931"
     CDS             35114..36382
                     /locus_tag="KRQ43_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742287.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNKNPKSRIRNDYLNIDKKYSDFVNDKG
                     KELIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     YQQNINEIKFSIGSKLYLEIVNNKSKNGDIEGHDSYSNLIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMIKNNKLNLIVTDMSNSIINLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGMKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            36748..37929
                     /locus_tag="KRQ43_001932"
     CDS             36748..37929
                     /locus_tag="KRQ43_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH2742288.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQVDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(38071..38988)
                     /locus_tag="KRQ43_001933"
     CDS             complement(38071..38988)
                     /locus_tag="KRQ43_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742289.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            39241..40035
                     /locus_tag="KRQ43_001934"
     CDS             39241..40035
                     /locus_tag="KRQ43_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742290.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            40036..42096
                     /locus_tag="KRQ43_001935"
     CDS             40036..42096
                     /locus_tag="KRQ43_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH2742291.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFACYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEELFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT        16400 a         4498 c         7256 g        14062 t
ORIGIN      
        1 taattaatag aaaattgtca tataattaat taagtagtat tattataaat aacattgaaa
       61 ggtagtggtt agaatatgga tatccataat aaatatgtaa attttataaa aaatatacct
      121 gtaccttttt tatattgtag aattgtaaag agacaagaag atatagaata tcgagtagaa
      181 tatataagta agggtatggg caaagtatta caattagaag aaggtatttg tgataaaaat
      241 atactagatg tattgcctgt atttaagtct aaaaaatatt tcaaagagtt gttctcaaat
      301 gaagtggatt gtataaaaag gtacattccg acacttaaaa actggataaa tataaaaaaa
      361 cagataatag gggattcata cataattttg tattttggta aaattgtatt tgattataga
      421 cagataatcg attcctttga taaaaaggaa aaagtagctt atattaaaga cgaagaaggc
      481 atatatatag attgcagtga aaatttaata ccaatattaa ataacaacat taaaacaacg
      541 aaagatatct ttggtaaaaa tgatatagaa gtatggggag agaatacagg aaaattattt
      601 agagatgatt atagaggagg agtatctagt aaaaaaagat ttttacaaaa tctttttgaa
      661 tatgaagaaa cattttttat ggttgaaaaa tattttttgt atgatgaaga cgaactttta
      721 ggtactatag ggataataga taatataata tatagtggtt acagtaatag aaattataac
      781 tcaaaagatt taatgaagat gatagaacac tcaattccag agaatatgtt ttataaagat
      841 gtgtatggaa attatattgg atttaattca ggttttttga atttagcttg tatgaataaa
      901 gaagaattat tagggaagaa tagttataaa atatcagaag aagaagcttt aataaataag
      961 atatttgaaa gtgataaggg tgtagttgaa aataaaaaag tagttacatt tgagttaaat
     1021 gtaagtataa atgatgaaaa taagtgtatt gagattacaa aaaggccgtt ttttgatagc
     1081 tatggaagtg ttattggaat aattggaaca gcaagggata taagtagaag aaaaagatta
     1141 gaagaggaaa tggataaaac taggatggaa ttttttgcaa atttatccca tgaacttaga
     1201 acgcctataa atttaatatc atcttcatta caagtgatag aaaaaaaaga agcagattta
     1261 atagaatcaa atgatacttt aaaaagaaat ttaggtataa taaaacaaaa tggaaataga
     1321 atactgaggt tagtaaataa tgttatagac tttacaaaaa tgcaatcagg atatttagat
     1381 tttaaaccag aagaatctga tataattgca tttatagagg agatatgtat gtctgtagct
     1441 gattttgcaa gccaaaataa tatacaactt acatttgata cagaaataga agaattttca
     1501 atgttatttg attcagaaaa attggaaaga ataatattaa atttactttc taatggaatt
     1561 aagtacaata agaaagatgg aaaaataaat atatttttat atgtgaaaga taatgtattt
     1621 aatatgaaaa tatctgatag tggaataggt ataccaaaag aaaaaataga taaaatattt
     1681 aatagatttg aacagattga caatgaactt tcctacagag ttaaaggaag tggtattgga
     1741 ctttcattag tgaaatcttt ggttgaattg catgagggaa gtatatcttt aaaaagtcaa
     1801 cttggtattg gaagtgaatt tatagtttca ttacctgtta gaagtgaaaa taatattgaa
     1861 aaatataatc ataaaagaga aatcagcaat gaactaagta aaaaattaga aatagagttt
     1921 tcggatttat aagtttaaat ataaaaaata aaattttaaa aaagtattga caattgattt
     1981 agaagggttt aaaataaatt acaacataat aaataaaaag gcgatgaata ggaagagtaa
     2041 atctaattcg attaccagag agaagagtcc attggctgga agacttttta aattagaggg
     2101 attgaaaact acctaggagc tactttctga agtcatctgc attagtagat tttagtaaga
     2161 atagtcgtta gctgcgttaa agtgtaaagt gagttttcat gatatatgaa aactaaatta
     2221 ggtggaaccg cgggaataat actctcgtcc ttatgttata aggatgagag ttttttgttg
     2281 tttaaaaata taaacagtaa tcataataat tatagaaaat ataaaagcga tgaataggaa
     2341 gagtaaattt aattcgacta tcagagagga aagttcacag gctgaaagac tttctaagtt
     2401 tgagaaattg aaaactacct aggagctgtg gtctgaagtt actttaaaaa gttttagtaa
     2461 gactaaccgt taactgcgtt aaagtgtaaa gtggatttta tcaataaatg ataaaatcaa
     2521 attgggtgga accgcgagta tagactcgtc cctttatata gggatgagtc tatttttatt
     2581 gcaataaaag attgaaaata aaaaaaaatc ggaaaattat aaatttagga ggaaaataaa
     2641 atggaaaata aagtgaaaat tggagtacta ggatatggag ttgtaggaag tggacttata
     2701 gatataatag ataataataa agaaaaaaga agtatagaaa tagttggaat tttagttaat
     2761 aatttggaaa aacataagga taaaaaatat tctaatataa taactaataa tatagatgat
     2821 atatttaata aagatataga tatacttgtt gaagtcatgg gtggtttaga accatcatta
     2881 tcttatataa aaaaagcatt aaacaataaa attcatgttg ttacagcaaa taaagatttg
     2941 ttagctgaat gtggagatga gcttgcaaaa ttagcaagtg aaaataaagt aagtattaaa
     3001 tttgaagctt cagtcgcagg aggtattcca gtattaaaac caataataga atcactagaa
     3061 ggaaataata tagatagtat aaatgcaatt ttaaatggaa ctactaattt tatattatct
     3121 aaaatgtatg atgagaatct atcttatgat atggcattaa gacaagctca agaattaggt
     3181 tttgctgaag caaatccaga gtcagatgta ttagggtatg atgctgctag aaaactatca
     3241 atattatcaa ctctagctta tgacaataga gtatattgga aggatgtgta tttagaagga
     3301 attacagata tagatgaaaa agatattgaa tatgcaaaaa aattaaattg taaaataaaa
     3361 ttgattggtc aaagtaagta tgaaaatgat aaagtaagtg cttttgttag acctgtttta
     3421 gtagaaaaag ataatatcct tgctagaata gacaatgagt tcaatgctgt catagtgaat
     3481 ggagattcag taggagaagt ttcttttgta ggtaaaggag ctggaagttt agcaacagga
     3541 agtgcggttt attcagatgt tatagatata atagataata gagtttcaag tatagattct
     3601 tttactaaag ataaaataca agttaataaa atagttagag aaaagtgtgg agcacttctt
     3661 agatttaaaa aatgtaataa agatgaaatt ctaaatatag ttgagaattg tttagtaaaa
     3721 ttcgatattt taaatgatga tgatgaactt gctattatgg tttatgctga ttctgaatat
     3781 gaaataaaca acagtttatg tctaataaaa gataaaggat attgcgaaaa aatgaataaa
     3841 atgttgaaaa taagttaaaa aagaaaaaat aagtttatat gtaacatatt ttgacgattt
     3901 taatactata tagtatgaga tgaaacaaaa catctcataa aaaattaaaa ttcaagggag
     3961 agatatgtta tatggaaaat aaaaaatatg caaatggtgg ttattcagaa gactggtatg
     4021 aaagaggaga atctacagct aaatggttcc agaatgatag agaagaatat gaaagagcag
     4081 catacgatga agatagagaa agaagaggct caaactgtgg atgttcagat tcaggaggaa
     4141 atagacctag aaactgtgaa agatttagaa gagaagctga gataagagaa agagaagcaa
     4201 gagaagcatt ctgtgaatct tcagagagaa agaaagaagc actagcatat gaatgtgaag
     4261 ctagaaaatt atgggaagaa gcagaaaaat actgggatga atattcaaaa tacaactata
     4321 aaggaatcga atatttagca gaagctgcta gattatttga tgaaggtatg gaatgtgaag
     4381 ctagaagaaa tggaaataat ggaggaaaca ataataattg ttgccataaa tgccataaat
     4441 gtaattgtaa ctgctgtaga aaataaaaaa attcattgac aaatcaatag ttaaaatata
     4501 tcatattatg tataataaag agaaaattca gaaaaaaata atgattagaa taaatttaag
     4561 tatatttatt agacaaatag tgctcagtta gtgaggtgag tacaatatga ttaaactccc
     4621 atcctctagc ttttgataga gggtgggagt ttttatttat tgatatatct taaatgagga
     4681 taatattgta aaataaatga gtatgagatt gtaaaattag gaggtaaaaa atgaaaagta
     4741 ttaaaacatc aagtatgaaa gaaaaggtag atgaaaagat attaagagag caagtaagtt
     4801 ctataataga agatataaga aataataagg atgttgcact taaaaaatat aatgagaagt
     4861 ttgatagaaa tacaagagat gaatttagaa ttactaagga agaaataaag gaagcttata
     4921 agcatgtaga tgacgaattt ataaataact taaagattgc tgccaaaaat ataagagaat
     4981 ttgctaaagc tcaaaaacta agttttgaaa acccttttga aaaagaaatt tatccaggtg
     5041 taatcttagg tcaaactaat attccaatag agtcatgtct tgcatatgtt ccaggaggtc
     5101 agtatccatt gttttcaaca gctcttatgc ttataatacc tgcaaaagta gcaggagtaa
     5161 aaagaatagt ggcatgttca ccaactatga aaaatactga aaagataaat cctaaaacat
     5221 tggtagctat ggatatagca ggtgctgatg aaatatatgc aactggagga gttcaagcta
     5281 tagcagcatt tacatatgga acagaaaaga ttaatccagt tgacataatt gtaggaccag
     5341 gaaataagtt tgtaactgaa gctaaaagac aatgttatgg acaagtagga attgattttg
     5401 tcgctgggcc aagtgaagtt cttataatag cggatgaaac ttcaaatcca gtttatattg
     5461 cagctgattt attagcacaa tgtgagcatg atttaaatgc aagaggaata ttattgacaa
     5521 atagcttgga agtagcacaa aaagttgaaa aaaatataga aagtatgcta aaagatttgc
     5581 caacaaagga catagcatat agttcatggg aaaataatgg agagataata ttggttgatg
     5641 atatggaaga agccattaaa ataagtaatt tttatgcacc agaacattta gaagttgcag
     5701 taaatgagta taatgatatt tgtgatagat taactaacta tggttcttta tttattggaa
     5761 atctttctgc tgaggtgttt ggtgactatg tttcaggtac caatcataca ttaccaacac
     5821 ttaaagcatc aagatatact ggtggtgttt gggttggaac ttttatcaaa acttgtacaa
     5881 agcagatatt taatgaaaaa gctatacaat cattagcacc tgtagctgaa aagctggcaa
     5941 aagaagaggg attatatgca catgcaaagg ctgctgaggt taggtttaaa aagtagtaaa
     6001 aaattttatt ttggcagtcg agatttagta ttagactgag ataaagaaaa cgctgagaac
     6061 ctgaataaat actatatttt gtgggcctcg gcgtttcttt tatatctgta tataatagga
     6121 taatactacc tgtgtgttta aatgctaact taatatttct tttctaaata atgtttatga
     6181 aatagttaat atttttagtt aatacttgaa aaaaactttt gctaactgtg caaattcatc
     6241 tgcatttgtc aatatagcag ggtgtcctcc ctgactaaaa atgtgaatac ttgcttttga
     6301 aataaaagtt gccatttgct tgtactcttc ttcaagatta tgacgacaca tttcgtcttc
     6361 cttacttcct gtaaataaaa ttggcatttc taatttacac aattctttat gaaataaagg
     6421 gcgtttcttg tttgcacatt gcaatagagc ttttgtatca agattaacaa cattctccca
     6481 atcttttcca tgacaccatt catagaattt tcgtgcttga atatcttgct ttgatttttc
     6541 ccttccagtg attagattat ctatgaagtt atcattaaga gtacgtccat caaagctatc
     6601 tgctataatt gcttcaacta aatcgggacg ttctaatcca gtattaacag ctgcccatgc
     6661 tcctccactt gttccaatta agccaacttt accacaattc aaatgttcaa tcagtgctat
     6721 tgtctgtaag gcttcatcat gccatatgtc aggagaaaat tgagaaactc tatcagactg
     6781 tccattacct aaaaaatcaa ttaagataca tctaaaattt tctacatata atggcacaag
     6841 tgctttaaac atattagaag aaccagtatt accatgcagg aaaattatcg gtttaccttg
     6901 tccatattct ttataaaaac aagaattacc ttgatactga aaatatgaca tatattttcc
     6961 tcctttttat ttgttaagtt aattataaca atataggtat gaatgaaaaa cctcatgttc
     7021 tttcttagaa taaaaatgtg ccacgcataa aacgtgacac atttctaatt ataaattttg
     7081 ctgtttaagt attctttgta tgcttttctc tgtcaaaaag tatttctctg ataactgctt
     7141 gatactcatt ccattttgga aatttataca gatttgagaa ttacgagaag ctaagacttg
     7201 tttggtgttt gtgttttcac cccaatgctt tttgtgctct tgctttttgg gaatataaat
     7261 cactttacca tctatatatt cttgcacttg ctcaatcagt tctttaggca gtaagtcaat
     7321 cgaattttga tagctcattt tgcacctcct aaataattac tctttaggat tagcaaaggc
     7381 tactgctact cacaattaaa aataaaattt tttattatgt acaatagcct ttgctatgca
     7441 caagttccaa ttcccataaa ctaaatactc ctttctggtt tgaaaaattc atctgaacat
     7501 tgatttcgat tttaagatag agttcaatga caaatttaca tttttattat atatattcag
     7561 atagataatt gcaactgtct ttgtatgagg atattttatt atagtcaata ctataatata
     7621 tatttatatc atcaaactaa tatgaacagt tgaaaggaat atgaacaata aaacttagtc
     7681 aggaagaata attatgaagc agacaattga gaaatttgat tttaaagttt tattgaaaat
     7741 ttattgacaa atttaacttg taaatattat actaaactta ataaataaag tttataaagt
     7801 aaggtgttgt ctatgaaaaa tatagttgga aaaccgcaaa cgataaaaaa agtaaatgaa
     7861 gatttaataa aaaacattat aaaaaatgaa ggtcctataa caaaaccaga aatttcaagc
     7921 attactgaat tgagtttagc tacagttaat aagattgtgg agcaattagc tttgaaaaat
     7981 gaagttaaag taagtggact aagtgaatct actggaggaa gaagagctca attatttgaa
     8041 ataaatgcaa acttagaaca cataatagct ttatattatt atagaaattg ttgtataggg
     8101 gtagttgcca atttattagg tgaaataatt tatcaagaag aatttaatat aagaatggat
     8161 acatatgaaa acgttaacca agatactttt tttgttatag atactctaat aaaaaaggaa
     8221 aaaggaaaca atataagggc tattggaatt ggtgtcccag gagttgtaaa aaaaggtgta
     8281 gttaaaaata taccaactat aaaaagttgg gaaggtataa atttagaaaa tttaataaag
     8341 agtaagtaca atactaaagt gtttatagaa aatgatacaa atattactac tattgggatt
     8401 tatcaaaaac agtataaaga caaatataaa aatatggctc ttatgtattt agaagatggt
     8461 attggttcag gtatagttat aaatggtgaa ttgtatttag gttctacaaa ttttgctgga
     8521 gaattaagtt atctaaatat agaatttggt aagtataact ctaacaactt aaatcttgaa
     8581 gattatatta tgagtttaag aaaaagatat ttagaaagta aagataataa atttaagaaa
     8641 gaaattttat ctataatatc aaactttata aggactcttg tatgtgtcct aaatccacaa
     8701 gctatgatta tacagtgtag tatattaacc aagagtgaca tggagtttat agaaaaagat
     8761 gtaagtaata atgttggaga agaaaatttt cctaaattaa taaaagtaga gtcattgaga
     8821 gaaagaagta taaatggagt aattagtatg tgtttaaaag aaactgacta tcaatattcc
     8881 ttatctaata aaaaaggagg atattaatgt gaaatatttg gtttcaatag atggaggggg
     8941 aacaaaaact aaattttgtg taagtgactt agatggaaac atacttaaag aacataccac
     9001 tggttcaact aattataagt cagttggaat taaaaaaaca tatgaaaata ttaataatgg
     9061 acttaaaaaa atattaaaag atttatatat cgattatgac gatattgagt acactgtatt
     9121 tggtatatct ggttgtgatt ctcctaatga ttataagatt ataatggatg aaatattaaa
     9181 aattgggatt aacaaagaaa aaatatatct ggcaaatgat gcagttttag ctttttatgc
     9241 acaagctgat tcccctggtt tagtaattgt ggctgggaca ggttcaatta tactgggaat
     9301 taaagaagat ggagaaatat atagagttgg tggatggggg tataatttta gtgatttggg
     9361 ttctggatat gatataggga gaaaattatt aaagaaagta ttgctttatt gtgatgaatg
     9421 tcatgagtat agtgatttat ttagttgtgt cttggatttc tttggagcaa atagttttga
     9481 acaacttgca tatatgatta ctgatataaa caataatgtt gaaatagcaa acctagcttc
     9541 attagtgatt gattgtgccg aacaaggtga taaattagct attgaaatat taagagaatc
     9601 atcaactgaa ctatctaaat tagctcaagt aatattgaga aaaatatcta atccaatgaa
     9661 aatagataaa agcgaaataa atatagtttt gtctggtggt acattaaata aaactgtata
     9721 tgctcaaatg ttaatgaata atttaaaaac agaaaataca gataaaaatt taaaatttat
     9781 atctcaagaa aatcagccag tatatggggg gataagactt gctatggcat tagctaatag
     9841 gagagttaag catggataga aaaaaggtaa tagtacaaat ttttactgga ggttttaagg
     9901 ctaaagaaat aaagtttaat gatataaaat gtaaactact agaattattg gactgtattg
     9961 atatagaaaa ggttatcatg ggatggagtg tagatgaaga attatatgta gaaactaaaa
    10021 aactattaaa taaatataat gttgaactat atctttggtt gccatgtttt tctgaaatag
    10081 gattacttga aaaaagtaat ttactaattg attatatggg gaaggaagtc aagggctatg
    10141 ctttacaaga ggatgaaaat tttgaatttt attgcccaaa taataaggaa aatataaaaa
    10201 atataaagaa aatatatagt acttatttta gtgatattaa atttgatgga atttttttag
    10261 ataaaataag gtatggttct ttttcgaata aactaaatgg tgtttttaat tgtttttgta
    10321 aagattgttt aaatatatat gaaaaaaata atattgataa aaagtcgtta atgagagaaa
    10381 tgaataatgt gtctaaggga gttatagata atgaagatac tccatctggt ataacagaat
    10441 acattaatgg aaaatacaaa tttaaaaata aaatatggga agattttttt gaaacaaaaa
    10501 atcaaaatat atacaagtca ttattagaga taagtagtta ttttaaaagt aagggattga
    10561 aaataggtat agatactttt tctcctttta tttcttactt tacaggtcaa gatttaaaaa
    10621 aattacaaga agtagcagat tttataaaac caatgatgta tagaactaca aaagctccag
    10681 ctggtttacc atttgaattt gaaaggttta ttgatgaatc catacataag aataaagaga
    10741 ttggaaaaag aaatttctta gatattttag gaattaaaga gtatgaagga gatgtatatc
    10801 ctatagaatt tgtactagag gaaatcgatt ttatgacaag gaatcttaat aaagatatat
    10861 atgtaggagt tgaaataaat aaaaaggaaa ttatagctcc tgttacacct aagtacataa
    10921 gtgaaaatat ttcaaatata aataagacaa cagtaaaagg atatgtttta tcttgggatt
    10981 tgttatcagc accaaaagaa aatattgatg aaattataaa atggtttcgg aattagtgag
    11041 gtgatatagt gagtaagata ttagaaatgc aacaaatata taaaagtttt ggaaaggtag
    11101 atgttttaaa agggataaat tttgagttag aaaagggaga agtaagagct cttttgggag
    11161 ctaatggagc aggaaaatct acacttatta aaattttagg aggagttcat tctcaaacta
    11221 aaggtaaagt aattttgact ggtaatgaaa taatgtttaa aaattcacat cattctaaag
    11281 aaaatggtat tagtataatt tatcaagaat taagcttgat accaacgctt acagtacttg
    11341 aaaatatttt tcttggtaga gaaattttaa aaggaagtgt gtttttaaac aagaaagaca
    11401 tgcttgagga atatatgaaa atttgtgagg attttgattt taatatagac ccacatacag
    11461 tagtttctaa tttaagtgta gcaaaccaac aaatggttga gataatgaaa gctgtttcat
    11521 gtaattctga aattatcata atggatgaac ctacaacatc acttactaat aatgaaaaag
    11581 atgggctatt taaaataata agtagactaa agtctaaagg taaaacaata gtctatattt
    11641 ctcacatatt agaggaagtt tttaaagtat gtgatagtgc aagtataatg aaaaatggaa
    11701 ttatgattgg aacttatgat gtagaggatt taactaaatt aaagataact caacttatga
    11761 caggaaatga taatcacaaa cttattgaga agaaggatta tacatttgca aagtatgaag
    11821 agccaccagt actagaagta aagaatataa gctggtctaa caaaataaaa aatgtttcat
    11881 ttaaagttta tagaggcgaa gttgtaggtc ttgctggtct tgtaggttca agaagaactg
    11941 aaattataaa tttgatattt ggtatagata ataaagatag tggagacatt tttatcaatg
    12001 gtaaaaaagt agacataact tctcctaagg ttgctataaa aaacaaaata ggattgattc
    12061 ctgaagatag aaaaaatcta ggattaattt tagaacaagc tatatacaca aactcatcat
    12121 cagtacaaat tgataaattc aagaaatttt tgtttataga tagaaataaa gaaattgagt
    12181 tttctaaaaa aggtgttaag gaattaggaa taaaagttag tgatgtaaag caagaagtaa
    12241 aagagcttag tggtggaaat caacaaaaag tagtagtttc taagtggtta gagaaagatt
    12301 tagatttaat aatatatgat gagccgacaa agggaataga tattgctgca aaagaagata
    12361 ttttcaatac aatcaaagaa ttttcaagtg aaggaatagg agtaatattt atatcttctg
    12421 atttagaaga agtaataaga gtaagtgata gaattttagt aactagagaa ggttctattg
    12481 tagatgattt aaaaaatgag aatatacagg ttcaagatat aatgaacagt atatttaatg
    12541 tataaaaaat gaaaatggag gactgagatg aagaaagctt ttgagaagtt aaatttaaga
    12601 gattatggag tattattagg ttttttagct ttatgtatag ctataagtat tgcaactcca
    12661 tcatttttag gtaaacaaaa tatacttaat cttttacgac aatcttctat aattggaata
    12721 atttcagcag gtatgacttt tgttataata tctggaaact ttgatatatc agttggagca
    12781 gtagcagctc ttgcaggtgc tataacaatg aaatttgcga ctggtggaac taatttgttt
    12841 gcatccatgc tcttaggtgt agcgatttgt gcagtaatag gattaatcaa tggtatagta
    12901 gttgcaaaga taaatgtacc atcattaata gcaactatgg ctatggtcac tattgtaaga
    12961 ggattgctgt tgatgcttac aggaggatat ccaattactg aaaatatacc aatacttgat
    13021 tacattggaa atggatattt gtttaatata ccaataccag tagtaatttt ctttatagtg
    13081 gtgttagttt catttattgt acttaataaa actaagtttg gtagatatgt ttattctgta
    13141 ggagggaatc aagaagcaag taaacttaat ggtataaatg tagattctca caaagtgaaa
    13201 gtgtttatta ttaatgctgt acttgcagga atagctggaa tcgtactaac aggaagactt
    13261 gggactgcaa ctgctattgc aggtgaagga tatgatatgg atgcaattgc atctgtagta
    13321 ataggaggta catcagtggc aggaggttct ggttctgtac ttaaaactgt tataggagta
    13381 ttacttatga gtgttataaa caacagtttt aatcttcttg gaatagatgt atatttccag
    13441 tacatattta aaggattaat aattttagca gcagttggat ttgattctta tagcaagaaa
    13501 aaacttgctt caagataaaa aataaggggg atttttttat gaaaaaatta atgaaacatt
    13561 tagcattgtt gttatcactt gttatgatat ttggtttagt tggttgttca aatggtggtg
    13621 acaaagaaaa aaatggagaa aagaaaatag cagtattact accaggttca acaggttact
    13681 ttgtagcaac taaacaaggt atagatgcaa aatctaaaga attaggtgta agcgtggaat
    13741 atgcagatgc tcaatgggat gctagtaaac aattatcaca agctgaagat tttatggcta
    13801 aaggggtaga catgattgca ttatgtggag ttgattctgc tgtaagtgag agaatagtta
    13861 aagctgctaa tgattcagac gtccctatag tagcatttac aaattctata ggaagtaacc
    13921 caactggaga atttaaaggt ttagttacat atataggaca aaatgaggag gaaacaggag
    13981 cactaactgg aaaaattgct aaaaacttat taggagaaac tggtgggaaa gctgtattaa
    14041 tagaaggagt accaggaact actccacaag tattaagaaa aaaaggtctt gaaaaagaat
    14101 taaaagatag taatatagaa atagtttata atcaaacttc aaattgggag aaagagcaag
    14161 ctttaaaagt aacagaagat ttaattcaaa agaaaactga ttttaatgtt ataatatgtc
    14221 aagatgataa ttctgctaca ggtgcaggtc aagctttaaa agatgctggt cttaaggata
    14281 aagttaaagt cataggtttg ggtggaagta aagatggatt aaaagctata actgatgggt
    14341 taatagatgg tacaacttat atgtctgctg tagaagaagg tggattagtc atagaaaagg
    14401 catctaaatt ccttaaaggt gaaaaaatag aacctgttac acaaattaaa caagttgaag
    14461 ttaacaaaga taatatttca gagttcaagg gtgaatggta aattgtcata gataataaat
    14521 aagattttta gagttacttt agaaactata taaagtaact ctttttttaa tttaatttag
    14581 tgataaatta ttgaatagta tttctaaaca aataaaaaat taatataaac aaagacttaa
    14641 ttatactaaa ttataagtaa aactaatata aacttatgga aaaaaggaaa acgtctaaag
    14701 tattggaatt actatagtgt aggtgtggta ttaaaaaaac ataaaaaaac ataaaaaaat
    14761 tgttgaaaaa aatatagaaa ttttgtataa ttaaagattt gaaaagttcg gtatacaaag
    14821 ccaattcttt tgtatataat atatataaat tcagaaaaag gaagggatat gtatggccag
    14881 gcggttattt ttagaaagga ttggacttat atttttaggt tcagcaatat tagcatttgg
    14941 agtttataat ttttattatt taaacaacat aacagaaggt ggagtgttag gtattttact
    15001 actgttaaaa aatttattca atatacaacc agcaatagca aatgttgtaa tagatggttt
    15061 actactttta gtaggatata aatttttcgg taaaaaattc cttatatatt caatagtagc
    15121 ttctataact ttttcagtgt tatatgactt atttgaagct ataggacctc tagtaccaca
    15181 atcacaaaat atgcttttat caactatttt ggcaggtgta actgttggaa ctggtgtagg
    15241 tatagtagta aaagcaggtt gtgcatcagg aggagacgat gctttagcat tagtaatttc
    15301 taagactaca tctttgaaca tagggcaagt ttatttagca acagatgtta ttgtattgtt
    15361 gttatcatta ttttatctat cagcgtttga tatcttttat tctttgattg ctgttacaat
    15421 tagtggcaag gtaattgatt ttatttatta tcatggtaaa agtttggata tggatataag
    15481 taatgatata gttccagaat gttaatataa attaaataac tttagatttt attaggggtg
    15541 gcagatttgc cacctttttt gtgtctaaat ctttatagaa agtataatcc catctaggtt
    15601 tttgcaaatc tcaaatatag aattatgttg gaatgactgg gaatacgatt gctagatgtg
    15661 cattttaaaa acccaatttt atatttatga aatactaatc attaatggat gtttcttaat
    15721 cctatcttta tacctaaaat gataagataa atgaagtagc aatacaaaac taaaatttgt
    15781 aaaagagatt aaattaaatg gaggagctaa aatgttggat atagttatga tagcattgtt
    15841 attcatagga tttgtttcca tgaagttact tgctgattgg tgtgggaaac aaactgagaa
    15901 aaaataatgt aatgtatgga gggattacct atgtggtttc tggcagttgt aattataatg
    15961 ttaataatat atttggtata tgcgcttatt aatcctgaaa aattttaaac agtataaggc
    16021 taataagtaa gttgaattgg ggggaacaat ttttatggtg cagatagtaa tagtgttagc
    16081 gatttttatg attttagtaa tacctatggg caagtattta tatcatatag ctactaatca
    16141 aaaaacattt ggagatagac tatttgataa agtggacaat tttatatata aggtatgtag
    16201 tatagataag aaaaaagaaa tgaactggaa acagtatgca ttagctttat tatttacaaa
    16261 tgcagttatg gtatttatag gatatatcat acttagaact caaagtatgc atatttttaa
    16321 tccaagtgga attaaaagta tggaacaagg actatcattt aatacaataa taagttttat
    16381 gacaaataca aatcttcaac attattcagg tgaatcagga ctttcatact ttagtcagat
    16441 gacagtgata atatatatga tgtttacatc agcagcaaca ggatatgcgg ctgctatggc
    16501 atttgtaaga ggtctagtcg gtaaaaagaa aacattggga aatttttatg tagatttaat
    16561 taggataaca acaagagtac ttttaccagg agctttaatt attgggctta tattagttac
    16621 acaaggagta ccacaaactt ttgctgggac agaaacagtg actactatag aaggaaagct
    16681 tcaagatata gctagaggtc ctgtggcagc tcttgaatca ataaaacatt taggaacaaa
    16741 tggtggtgga ttctttggtt caaattcatc acacccattt gaaaatccaa caataatatc
    16801 aaatatagta gaaatattat ctatgatgat attaccagga gcttgtgttg ttgcattcgg
    16861 tcacatgata aagaataaaa aacaaggttg ggttgtgttt ggcgcaatgt caatcatatt
    16921 tttaataggt ctagtagtgt gctttaaagc agaaagtgca ggaaacccta ttttatcaca
    16981 attagggctt aatcaaagta tgggaagtat ggaaggtaag gaagttagat ttggtatagc
    17041 acaatcatca ttattcacaa cagtgactac ttcctttacg acaggtacag ttaataatat
    17101 gcatgataca ctgactcctt taggaggatt agtaccactt ttaaatatga tgctaaatgt
    17161 agtatttggt ggtaaaggcg taggtctgat gaatatgttg atgtacgcta taatagcagt
    17221 attcttatgt ggattaatgg taggaagaac accagagttt ttaactaaga aaatcgaagg
    17281 aaaagaaatg aagcttattg ctttacttat tatattacat ccacttttaa tactaatgtt
    17341 ctctggtctt tcagtagcaa taccagcagg gcttgaagga atttcaaatc ctggattcca
    17401 tggattatca caggtattgt atgagtttgc atcttcagca gccaataatg gttcaggatt
    17461 tgaaggtcta ggagataaca ctatgttttg gaatataaca acaggtatag ttatgttctt
    17521 tggaagatat gtgtctatta tagtactact agcaatatca agtttgttag catctaaaaa
    17581 agctgtaaat gaaagtatag gaacacttag aacggataat tttacattta caatagtttt
    17641 agtacttgtt gttttaattg ttggtgcttt aacatttttc ccagccttag cgcttggacc
    17701 tatttcggag catctagtgt tgtggcacta aaaaattggg agggagtaaa gttttatgga
    17761 aactaaaaaa acaaagttta ttacaaaaga tattttcaaa acttccatta tagaagcttt
    17821 taaaaaatta aatcctaaat atatgatgaa aaatccagtt atgtttgttg tagaaattgg
    17881 atttatagta acattgatac ttacaatagt acctagtttg tttggtgatg aaggcaataa
    17941 tttaagagct tataatggga ttgtaacaat aatcttattt ataacagtcc tttttgcaaa
    18001 ttttgctgaa gctgtagctg agggaagagg taaagctcaa gcagatacac ttaagaaaac
    18061 tagaaaagat acagtagcaa gggttataga tacgttagga aatgaaaaaa tgataagtgc
    18121 aagtgagcta aaacttggtg atattgtttt agtaaatgtt ggagaagtta tcccaaatga
    18181 tggagaagtt atagagggca tagcttctgt ggatgagtca gcaataactg gagaatctgc
    18241 acctgtcatg agagaatcag gtggagattt cgcatctgtt acaggtggta ctacagttgt
    18301 aagtgactgg ttaaagataa gaataacaac aaaaccagga gaatcgttct tagataaaat
    18361 gatagctctt gtagaaggtg cttcaagaca aaaaacgcca aatgagattg ctttaaatac
    18421 tttgttagta gggttaacac ttatatttat ggttgtttta atatctcttt atccaatggc
    18481 aaactatgca ggtgtaaaga ttccaatttc tactatgata gctcttttgg tatgtttaat
    18541 accaactact ataggtggat tgttgtcagc tattggtatt gcaggtatgg atagagtaac
    18601 tagatttaat gtaattgcaa tgtcaggaaa agcagtagaa gcttgtggag acgttgatac
    18661 tatgattttg gataagacag gtacgattac ttatgggaat agacttgcat cagaatttat
    18721 agcagttgga aatgcagatt caaaagattt aataaattat tctgttatgt gttcattaaa
    18781 agatgataca ccagaaggaa aatctatagt tgatttaggt atgaaattag gttcaacagg
    18841 taagacaaaa gaggcagagg aagctgagtt tgtagaattt tctgcacaaa ctagaatgag
    18901 tggtattaac ttagctgatg gtagagctat aagaaaaggt gcttatgata gcataataaa
    18961 aagagtaaaa gaatctggtg gtacagtgcc agaagattta gaagaaaatg taaatcgagt
    19021 agctaaacta ggaggaacac ctttagtagt gtgtgtagat aatgagatat atggaattat
    19081 ctacttaaaa gatacagtaa aatcagggct tgtagaaaga tttgctagac ttcgagagat
    19141 aggaataaag acaataatgt gtacagggga taatcccttg acagcagcta caattgcaag
    19201 agaagctgga gtagatggat ttattgcaga atgtaaacca gaagataaaa tagatgctat
    19261 aaaaaaagaa caattagagg gtaaaatagt tgcaatgaca ggtgatggaa caaatgatgc
    19321 tcctgcactt gctcaggcag atgtaggtct tgcaatgaat agtggtacaa catctgcaaa
    19381 agaagcagca aatatggtgg atttagattc agacccaact aagatattgg aagttgttga
    19441 aataggaaaa cagcttttaa taactcgtgg ggctttgaca acatttagta tagcaaatga
    19501 tgttgcaaaa tattttgcga ttataccggc tatatttact cttgcaatac ctcaaatgga
    19561 gatattaaat gtaatgaaac tttctacatc atttagtgcg atattatcag ctttaatatt
    19621 taatgctata attatcccat gtttaatacc tcttgcaatg aagggagtaa aatatagacc
    19681 tatgaaatca caagctatgt taatgagaaa tatgcttata tttggtcttg gtggagttat
    19741 agtaccattt ttaggaataa aattaattga tttattgatt acacctttag taatgattct
    19801 taatttaggt taataaatgg aggatataaa aatgaaaaca ttaaagccag cattacttgt
    19861 aagtattgta ttgttagttg tttgtggact tgtatatcca cttgttttga caggtgtaag
    19921 ccaagttgca tttaaagata aagccaatgg aagtatgata gaagtaaatg gtgtaaaagt
    19981 aggttcagaa cttattggtc aaagctttac agatgcgaga ttctttaagg gaagagtatc
    20041 atcagtaaac tataatactt atacaaaaga agatttagta ccagataaag atggaaatgc
    20101 atcttatgga ggtgtatcat cagggtcttt taattatgga gctacaaatc cagaacttca
    20161 tgatagagta caaaaagata tagaaaagtt tttaaaggat aatccaactg tcaaaagaga
    20221 ggatatacca acagatttac ttacagcatc aggttcagga cttgacccta atataagtcc
    20281 agcctctgca aaaattcaga taccagctat agcaaaagcg tctggaatat cagaaagtaa
    20341 attacaaaaa attgtagatg ataatacttc caaaaaactt tttggagttt taggtgaaga
    20401 tagagttaat gtactaaagg ttaatataga ggtcgcaaaa atattaggtc ttatatagta
    20461 ttttgtggaa ttttagtaac aaaatattac tcaagattta atttaaaggt taaattttaa
    20521 agagtgaaaa tcaataatga ttttcacttt tttatttgaa tattactaat atttggaata
    20581 aagtgattgt aagtataaaa tccaaaaaaa ggttgcatta tcaaaatgat aatactataa
    20641 tatatttatc gttatcaatt tgataataga tttggacata taggaggaaa tagtatgtta
    20701 tataataacg cattagagtt gataggaaac acacctgtag taaggctgaa taatttaggc
    20761 tgtactaatg ggtgttctaa catatatgta aaattagaaa aagtaaatcc agcaggaagt
    20821 ataaaagata gagctgttta tgaaatgtta gagggcttag agcaaagagg agaattaaaa
    20881 aagggagatg tactagttga agcaactagt ggaaatactg gtattgcatt atctatgata
    20941 ggaaaattaa aaggatatga agtagtaatc gtaatgcccg aaacaatgag cgttgagaga
    21001 agagatttaa tgaaggctta tggagcaaat ttggtgctta cagatggtaa agctggaatg
    21061 gcaggttcca tagaaaaagc aaatgaactt ttaaaagaaa atccaaacta taaaagctta
    21121 aaacaatttg aaaataaaga taatccaaat gcacattata aaacaacagc agttgaaatt
    21181 atgaatgatg tcaaagattt agatatattc gtatgtggag ttggaacagg tggtacttta
    21241 ataggaactg caagatattt aaaagaacaa aatccaaaca taagagtaat tgcacttgaa
    21301 ccaaaaaaat ctccagctat atcagaaaac aagactggac ctcataaaat acaaggaata
    21361 ggtgctaact ttgttcctga aaattatgat tctagtgtag ttgatgaagt aatattagta
    21421 gatgatgaag atgcatttga tacagttaaa ttacttgcag caaaagaggg aattttagta
    21481 gggatatctt ctggagcaaa tatatttggt gctatagaga tggcaaaaaa gtatccagat
    21541 aaaaagatag ttacagtagc tccagatgga gttgataagt atatgtctat gggaatattt
    21601 taataatttt atttgaggga gtgaatactt tgtttaagaa aataaataaa gatattgaat
    21661 atataatgaa gaatgatcca gcagctaggt ctaagataga agttttttta ctttatccat
    21721 cagttcatgc aatgataatg cataggatgg ctcatgctct ttataagaag aagaagcttt
    21781 ttacagcaag attaatatcc cagatatcca gatttatgac tggcatagaa attcatcctg
    21841 gtgctaaaat gggggaaggt atattgatag accatggaat gggtgttgta attggagaga
    21901 cagctgaagt aggtaatagg gtgacaatat atcaaggagc tactttagga gctacaggaa
    21961 aagatactgg aaagagacat ccaactgttg gtgatgatgt attaattggt gctggaacaa
    22021 aaatactagg acctttaaat ataggttcaa attcaaaaat tggtgcaaat tctgttgtcg
    22081 ttaaggatgt acctaatggt gcaacagttg ttggtatacc agcaaaaata gtaaaaataa
    22141 gaaacctaga acctgtaaaa aagaataaaa aagaagtgtc ctatgagtat gatgaattag
    22201 ataatgtata ttatatatag gatttatata actataaaat aaactttata aaaattattt
    22261 taaaaggtat ttttttcaaa tttgaggaca taataaaaaa gaactgaatg ttacagtttt
    22321 ggttcatcaa tctttgataa acaagatttt aaatttgtag cgtctaggag gattttatta
    22381 tgaaagcaaa tgttaatcaa gatacttgta taggttgtgg attatgtcca tcaatatgtc
    22441 cagaagtatt tgatatgaag gatgatggga aatcacatgt tatagttgat gaagtaccaa
    22501 gtgatgctga agaatcagca gcagaagcta gagaaagctg tccagttgat gcaatagatg
    22561 tgcattaata aaataaatgc ctataaaaat tgaattttca atttttatag gcatttgtct
    22621 tttattcagt tagtatttca acccctgttt ctgtaactaa aaccatacat tcccattgag
    22681 cagataattt accatctttt gtataaatag tccaattatt ttcttcatca acaaaaattt
    22741 cgtgagttcc ttcatttacc ataggttcta ttgtgaatat catcccagga accaatagca
    22801 tctcagtccc ttttttagat acataactta caaaagggtc ttcatgaaag cttaatccaa
    22861 ctccatgacc acctatttct ctaacaacag agtatccatt tttctttgca taagagttga
    22921 tagcatcacc tatatctcct aaaaatcccc atggtttggc aacttcaaga cctttttgga
    22981 cacattcctt tgtaacttga actaattttt ttgcattttc attaacatta cctatcataa
    23041 acattcttga agcatctgaa tagtatccat taaaaatagt agaaacatct acatttataa
    23101 tatctccatc ttttaagata atgtccttgc ttggaatacc atgacaaact tcattattta
    23161 ctgatgtaca tacactttta ggaaatccat tatagtctag tggagcaggg atagctccat
    23221 tttgtagtgt aaagtcatga accaacttat tcatatcttc tgtagacatt ccaatttcga
    23281 ttttatctga aatataatcc aaaatttttg tgtttattac agcacttttt tttatttcct
    23341 caatttgact ttcatttttt ataatatcat gagttggtac aatatgacct aacttagcaa
    23401 atgaatctat tttattatcc atatccatat gacatttttt atatttttta gtacttccac
    23461 accaacagct atcatttcta tttaacttca taacttttca tccttctttt attatttatt
    23521 taaattatgg gttacataaa ctattttaaa acataaccat tataaatatt ataacataaa
    23581 tactaagaaa tcctttatag atagtgattt attcaaagta taaattatta tatggttatt
    23641 gttgatgaaa agaggatagt taaatgtatt attggatatt agcgcactta atagtttagt
    23701 tcaagttttt caagaaaatc atatgttaga ggacaatttt cctttaaagt attttttgaa
    23761 tcttcatcaa gataataatg cacaaatgat tctgcaaaaa attcttctat aaacttgctt
    23821 atatatgcat gtgcaacttg tttagggtca taaagcttat atctttcctg agcaaatact
    23881 tccataaatt cttcagaatt tgatttttta tttaaaacat ttttatctat agcatgtgca
    23941 gtttcatgta attctaaatt ttttgatgaa tgtacatttg catagctagg gttactataa
    24001 cctattttag ctactataga attatttcta tatataccag gtacatcttt ccaagtcttg
    24061 cctgatctta cccaacatgg aggtaattga tattttaaat cactaaattc tggttcatca
    24121 gttagatttg aatttattaa ttttattttt atatcctttt ctttaagtgt ctgtaaatat
    24181 ttaatattta tttttgcaag tctgcttttc atattttcaa cttcatcttt atcataattc
    24241 aagtcatcag gaagtataag catttgttca attatatcta tgctactgtc ttttatatct
    24301 tcagattctt catcaaattt atattgaaga gtattatttt catagatagt tatatttgta
    24361 ttattttcca tataataaga gtgaatatcc tctaagtcta aaatattcat ttgttgtaaa
    24421 atatgttttg tttcgccact ccatactact aaagaaagtg aattaaaatt aattagtgga
    24481 ttttcctttg cttttatatc attgcttata tctacatcaa atacatattc aattgagtct
    24541 tctatgttaa gactatctgt attcttttta atatataaat atgcttgttt taagtctata
    24601 taaatctcat ctaaagattc atcataaaat tctgataaat tattagtaaa gagttcttca
    24661 cttaaaagtt catttttatc agttatactt tcaattaaaa tattaatttc ttttatcata
    24721 tcgtaaatac ttatttttct atttgctttt tcactagata cattgcatgg cgcaagagca
    24781 atgcaataaa aatctttttc ttttttataa aaggctttaa gtgattttga taaaagtgta
    24841 aagtctacac ctatctgtaa gttgacctta agtgagtcat tttgtaataa ttcagtatta
    24901 ttttttttag ctatatttaa attgttttcc ataatcattg cccccttttt attagggtat
    24961 cataattttt ttatatgtgt caatttgttt ttttgaaaat tataattttt ttgaaaattt
    25021 tattttttat aatttgtgaa ttttttatta tagaaataaa tatgttatta ttatgtcaaa
    25081 atttagcatt agattcatgt agagtatgtt ttatacatat attataatta attctttgaa
    25141 gattgcatat tcaaaataca caccattttt tttaattcta taatataata tttatatatt
    25201 taatgttagg atgtgattta aggtgtattt tacatatatt ataagatgta aagatgattc
    25261 tctatacact ggatatacca gtaatatagt tagaagaatg aatgaacata agttaggaat
    25321 taattcaaaa tacacaagag caaagggatt tgaaaaacta gaagtttatt ttgtgaccaa
    25381 cacaaaaagc aatgctatga agttagaata ctatataaaa aaattaacta gaaataaaaa
    25441 attgtctata ataaaaaacc caagtatact tataaattta attgataata aagaagatta
    25501 tattattggt aaggaaatag aacaattaac ataaatattt atagtaacat tataatgggt
    25561 gcatatagtg taaaaacttg acaataaata ctattgtaat ataatgaagt tataaatata
    25621 gtaaattaaa atagctaggg gagccaagag ctgagaggta taccgaccct tacacctgat
    25681 ctggataata ccagcgtagg aaagcttagt aaaaattcaa gtatgtatta tttgtgatat
    25741 atgctatttc taagctatac ctattgtagg tatagctttt ttaattaagt tatttaaatt
    25801 aaactttagg aggcaacaat gagtaattat aaaataccaa cacttacaat agctggctct
    25861 gattcatctg gaggagctgg gattcaggct gatttgaaaa cgtttagtgc aattggtact
    25921 tatggtatga gtgtaataac agctataaca gcacagaata ctaaaggagt ttttgctgta
    25981 gaggatttaa ataagaaaat aataaaaaaa caaatagagg cagtctttga agatatacct
    26041 ccaagagctg taaaaatagg aatggtttca agtcctgaga ttatacttga aatagttgag
    26101 aatctaaaga aatacaatcc aaaatatttg gttgtggacc cagtaatgat atctaaaagt
    26161 ggatattatc tattaaagcc agaggcaaaa gaaaacttaa ttaagtattt gataccactt
    26221 gcatacataa ttacaccaaa tataccagag gcagaagaaa taacaggaat aaaaatacat
    26281 aatgtagatg atatgaagag agtaggagaa gaaatactac aacttggacc taaatttgta
    26341 cttatgaaag gaggtcattt agatggagaa gcagtggata ttttagttgg taaaaatata
    26401 tttaaagttt ataaaagtga aagaattgat aaaaaaaata cacatggaac agggtgcaca
    26461 ttatcttctg caataacatc ttatctagca ttaggatatg aaataacaga agcagtaaat
    26521 ctaagtaaaa tctatataac agaagcaata aaaagaagtt ttgatatagg tcatggagta
    26581 ggaccagtac atcattttta taaatttgag taataaaaaa atattggagg tagaatatgt
    26641 ataatttaat taaagatgta aaaaaattaa atccattggt aattcattat actaataatg
    26701 taactataaa tgattgtgct aatgtgactt tagctgtagg agcaagtcct cttatgagtt
    26761 tttcatatga ggaagtagaa gaaatggtaa gtgtagcaaa ttctgtagta ataaatatag
    26821 gaactatgaa ctcaaatatg ttggatttat ttctattagc tggaaaagca gcaaataagt
    26881 acaataaacc tgttgttttg gacccagttg gagtatttgc aagcaaagcg agagcagaac
    26941 ttacaagtag acttttaaat gaagtcaaat ttagtgttgt taaagggaat gtatcagaaa
    27001 taaagtttat aggtggcttt aatgtaaggg gtaaaggtgt agattcattt gatgaagaag
    27061 aagattctac tgagataata agaaagattg ctgaaaagct tgaatgtgta gttgtagcaa
    27121 ctggaaaaat agatataata actaatggta aaggtatata taaaataaac aatggaactg
    27181 ataaattaaa aggaattaca ggaactggat gtatgactgc tagtttgatt gcaagtttta
    27241 tggctgttac tgagaatata ttagaagcag caacaatggg tgttcttaca atgtctttaa
    27301 gtggggaatt agctaattta aataatccac caataggtac atttaaagaa aatcttatga
    27361 atgctattta tcaaatggat atagatactt taagtaaaaa ttctaatatt gaatttttaa
    27421 attaataaag agtaagggag acttaaaatg attgataaag aatctttaaa aaaatgctta
    27481 aagttgtatt tggtaactga ctctgaaatg cttaaaggta gagactttta taaatgtctt
    27541 gaagatgcaa tatcttctgg aataacaact gtacaactta gagaaaaaaa tgcttctgga
    27601 agagagtttt taagaaaagc tatgaaactt agagaaataa ctgaaagata tggtgttaag
    27661 tttataataa atgatagagt ggatatagca cttatttgtg atgcagatgg agtacatgta
    27721 ggacagagtg acattgatgt gagagaggtt agaaagctta taggaaacaa taaaattcta
    27781 ggagtatcag caagaacttt agaagaagct acttgtgcaa aaaatgatgg cgcagactat
    27841 ttaggtgtag ggtctatatt cacaacatct actaaattag atgcaaaatc agcttcgttt
    27901 gaaactgtta aagaaattaa agaaaaagta gacatgccat ttgtgctaat tggaggtata
    27961 aatttagaca atatagataa acttaaatgt ttagaaagtg acgggtatgc tataatatca
    28021 gctatattaa aagctgaaga tatctctaaa gaagtggaaa agtggacatt aaaaatataa
    28081 aattggctct ggtagtgaaa aaaatggaaa aatttgatat aatctaagag taaaatttaa
    28141 gcaattataa atgataaact tttctacata tactttttaa tcaagatata tgtagatttg
    28201 gttaaaaagg agctataaat gattaagata ttgttagtgt gtgttggagg catgtcttct
    28261 accctattgg taaataaaat ggagaaggat gcaaaaaaaa gaaatataga ctgtaaaata
    28321 tgggcagttg gagaaggaga tataaaatcg gagcttgata actttgatat tttacttctt
    28381 ggaccacaac ttagatttat gcttgatgac gtaaagtcta tagttggaga tagagttcca
    28441 gtatctataa tagatatggt aaactatggt acttgtaatg gtcatgctgt gttaaattcg
    28501 gttttagaaa tattaaaata aataataaaa gtggattcta tataatagag tccattttta
    28561 ttatttgtta ttaataggct taaaacttag cttaccattt ctttttttaa tctccacata
    28621 gcaagtgaaa aacttgaaca gcacaatatt aaaaatagta ggataacagg cagtatatct
    28681 ccaataagaa tagtctcacc aaatattaag ctacgtaaag cgttaataac atgggtaaat
    28741 ggattgagca tcactgctac ttttaatcct ccagataaac tttctatagg gaaaagagct
    28801 gaacttaaaa agaaaatagg aagtacaatt gcagtcataa ttgtttcata aactatttca
    28861 tttggcaata ataaacttat agaataagct agacttgata aaaagaaggc tgtcataaat
    28921 atcagtacta tcataagtag gattccacca atgccagatt ctatccttac tgagaagaat
    28981 atacttacta tacacaaaat agttacttct atgaaggaaa ctaagatagc ttctaataat
    29041 tgaccaagga cgattgaata cctactgata ggtgcaatta agactctata gaaacttcca
    29101 ctgttcttca ttataaagtt tataatacca ccactactac aagaagaaaa cacaaccagt
    29161 acaatgatac ctggtagtat aaaagcagta taattattga tatttatatt attcatagtt
    29221 tggtttgcaa tagaactata aagcacaagc caaagaaaag gttgtaatat agtaactaca
    29281 aatgagattg gatttttaaa acgccacttc atactacgcc ataagatatt taacattccc
    29341 attcctcctt taagcttttt ttagaacttg taagtgctaa aaatacatct tcgagacttg
    29401 gctctacaat ttctattgca tcaaattcta tatcatgttc taaaagccat ttatttatta
    29461 aagtaaaagc agttctacta tcgtttacac ttataaaaat tgaattttct cgtacgctca
    29521 taaactttac taaaccagta cttttaattg aatctttata tttttttata tcttcagtat
    29581 tatggaaagt tatacgtagt atattttgtc taatgtaact acgtaaactt gatggtgttc
    29641 cttgtgctaa atcctttcca ttcttcataa tacaaatatt atcactcaat tgttcagctt
    29701 cttcaagata atgagtagtt agaaatatag ttgtgccgta ctcatctcta atttttaata
    29761 acatatccca catagatttt cttgaatcga catccatacc aacagttggt tcatctaaaa
    29821 ataggatttt aggagatgat accatattca tagctatgtc caatctacgt tttacacccc
    29881 ctgaatatga tgaagtagga tattttaagt aactagataa gtcaaactta tcaattaaag
    29941 agtctattct ttgttttgca atctgtggtt ctactttata cattttactt tgaaatacca
    30001 tattttccat aagggataaa tgttcatcaa tagagatttg ctgtgctaca caagcaattt
    30061 gagtacgtat ccaagaagga ttatctacta aatcttttcc aaacattttt acatttccag
    30121 atgtaggttt gtaaaaggta gtcaaaatat ttataagaga agatttacca gcaccattag
    30181 gaccaagtaa agaaaaaatt tctccagcat ttacattaaa gcttagacca tttaaagctt
    30241 tcacaccatt tttatattct tttactaaat tgtctatttc aatcgctaac atatattatt
    30301 cctcctcttt aagtggaaat attatctctg taatatagtt atctgggttt ccttttatca
    30361 acatacctgg tcctttaata aatacttctc tccaaggagt ttgtattttt atattatttt
    30421 catgaatata tttaaatatc atttcatacg tttttggcaa attactataa gagcctgtgt
    30481 gagtaaaaaa taaagctttt gttttaggaa attcttttgt agttataccc atacgatttg
    30541 gagtttcagc agttggaaca cataattcca tttctgcaac accagttttt tggtcaacat
    30601 catagtagca aaagaatggt gcaccgttag actttccttt tatagcttta aatacatttg
    30661 gaaaatactt tgttgcctca gtcataggtc cattataacg catggtagcc actgtgactg
    30721 attcgatatt tttgatttca attttgcaat tcatttgttt acctcctaat gtgtgttcat
    30781 attcttacta gatttttaag cattaataca tataagattt tgattagttg aaaacatata
    30841 atcttatctc gtttgcttgt tttcaagtct aacataacat aaaatatata tcctctcatt
    30901 tgatgctcca ttttgtaaag ctattattta agctttactt tagatttttt agcaaattga
    30961 aataaagcaa tttataaaat aagtatttac aaattaagtg tattaatcgt ataatacact
    31021 taataggata ctagataaag tctgaaataa aggcgtattt ttttaaagta agtgtactat
    31081 cgtattaata cactagaata ggaggaatca tgaattttga attagataat acaactccca
    31141 tttatttgca aatagtaaag tatataaaga gacaaatagt aacaggagag ttgaaaccag
    31201 gagagacaat accatcaaga agagaaatgg cacttaatct aaaagtaaac ttaaatacag
    31261 ttcaaagagc atataaggag atgggtgata tgaatataat aaatactttt aaaaattatc
    31321 aaagcagtgt aacagttgat gaaaatatat taaaaaattt aaaattagag cttataaatg
    31381 aatcactatc tgtttttata gaagatatga aagcaataaa tgttagcaaa gaagaagttt
    31441 taaaaataat agaagataag tattagtttt ttaacaaata gaaaacttag tttagaaagt
    31501 ttatttataa gcatattgga tgtggaggat agtaaatatg atagaaataa agaatgtcag
    31561 caaaacatat aaaaggatgc aagggcttaa aataagaaag atagaagctt taaaaaatgt
    31621 aagttttaat atagaaaagg gaaaaataac tgcattactt ggtataaatg gtgttggtaa
    31681 atcaactatg ttaaaagcaa tagcaggact tataaacatt gatagtggag aaattcgtat
    31741 agatggagaa aaaataaatg aaaaggtata caataaattg gcttttgttc cagatgtaca
    31801 atctcacttt agcaatacaa caataaaaga aacatttgaa tttatggaaa ttttttattc
    31861 aaagtggaat aaagaaaaat caaaagaaat gatggacata tttaaattgg atgaagatga
    31921 aataattgat aacttgtcaa aaggaaacat tgcaagagta aaattaatac ttggattttg
    31981 ccaagaccca gagtacatac ttcttgatga accatttaca ggaattgatt tgtttaagag
    32041 ggaagagttt ataggagtaa tagcgcaata tatggaggaa aatcaagcca ttatcataac
    32101 tactcatgag atagtagaga tagaaagttt agttgatgag gttgtaattc ttgatgaagg
    32161 gcagattata acttcattta atgcagaaga attaagagaa agagaaggta aatctatatt
    32221 agataagatg agggaggtat ataagaatga ataaacttct atatctaata aatgtagatt
    32281 tgagaagaag caataagttt tatatagctt atatatcatt tttttcatta attacactta
    32341 gtttaaattt attcgaaatt aataaattta aaaattctaa atttattatg aacttagcaa
    32401 tagaagattt tggaggtata ttttatggac tagggatact tagtaatctt ggttttatcc
    32461 aaaatatatt gttctttgga atgttgggac tttttatata ctatattttt atgtggaaaa
    32521 gagagttctt ttcaaataat caaagtattt atacacttat gatgttacct caaaataagt
    32581 ttaagatttg tatatctaaa tcaatagttt tgataacaat gatatatggt tttttgataa
    32641 gtcagacagc aacattattt atatgtaaat atatatttaa tttcattttt agaaatattc
    32701 ctataatcaa tatgaacttt gccaaagatt tatattattt aaacttgaag agtataccaa
    32761 ttgattttat ctcttttatg gctatttatg tatttttact acttatagct atttctattg
    32821 taaattgctg tatattattt atcttttcct atataaataa attttatgta attttaatca
    32881 ctttgctgat tatagcaggc ttatattttt caacaatata tataaatata atcaatttat
    32941 ttagaaaata ttataatctt ataggatttc aatttaacaa tttagtagca gggttattaa
    33001 gttttttaat tataatgttt attctaaatg gaatatctta tttgctaatt aaaaagaaag
    33061 tatctcttta aggaggggtg gtatgaaatt aaaatctaaa atatctatac ttattatatt
    33121 tttgacttta gcaatatatt ttagtatagg tttattaaat aatgaagata atttaaagat
    33181 aaaaactata aaaggtgact ctaatgaatt agaccatata aacataaatt ttggatatgc
    33241 tttgaatgga tatataaatt catattatac aataaatgga agtaacaaaa ctaaaaagac
    33301 tgaattaata aaactacaaa aggatagtaa gaacacaaat aatttaattg atgtatctag
    33361 tggttcagat ttaattgctc atgttggatt tgaaatgaat gaggagtcaa aagatataaa
    33421 ctttgtgata gatgagaaaa aagaagattt agaaaaaggt gtatttccat cagaaggtag
    33481 tgataaagaa attgaatatg aaaaattaga tatgaataat tttacaagga caagatataa
    33541 agtagataaa agtacagatg attattatgc aaatatacta gcatcaaaaa gatataaaaa
    33601 atacttatat gtatctgtac tttatgctac aagtgattca tcagaaaata acaaagaata
    33661 ttcaagtact atagatataa taaaaattaa tccagaaaat aaaaaaatca agactataaa
    33721 aagtataaat ttaagtaatt atttttccga gaaataccaa gacatagaga acataggtgt
    33781 aagttatgct agcaaatatg aggataagat gtatatttta gtaaatgtac taaatacaaa
    33841 cataggtgat aatagtaatt ctaaatttca tttacttgag tataatcttg aagaaaataa
    33901 ggaaagcata atggaattaa aaactgatag caaaatggct ttagcaaaag caaagttaga
    33961 agctaataaa ttatatatgg taatgtcgaa tgattatgat aatagttcaa ttacagagtt
    34021 aaatttactt acctataata tattagataa aagcttagat gaagataaat atgttttaga
    34081 taatagagaa aaaagaggaa ttagaagtat tgaaattgat tcaaataaaa tcgttgcata
    34141 tacatcaagg ctaaactcta tattatcttg ggataataaa tttatgctat atataataaa
    34201 taaaaattct aaggaaattg tatatgaagg agaattacaa tttaacagtt caaatagtat
    34261 gttagaattt gaaataaagt aggtgagttg atgaaagatt taataagatt attcgaattt
    34321 gaattaaaaa gaaatataaa gaattatata tttataataa tttgttgttg ttcttttgta
    34381 attttaaaca tagtaaaaaa tttaaatgac tataattaca taatagaaaa tgcagttaaa
    34441 agtgaacagt taacaaaaat cggaaatacg atagaaacgg taaatgttac aggtttctca
    34501 agctttagaa atataatggg ttctacagaa tcgtggttta tatttggtat aattgcatgt
    34561 atttgctatg ctttttttat ttggtataga gactttaatg gtaggagtaa atctatatat
    34621 acacttataa tgctacctaa aaatagaatc aatatttata tatctaaatt attaaatata
    34681 ttatttctag tgtatagcta tacagtagta cttacaatat ctttgtttat tgcaagtaag
    34741 ttgttgccta gacatatgct tggtaatgtc acaaactatg gttttgtaca agaaacaata
    34801 tatgagttaa aaatgttact tccatatagc tttgaaatac tatttgtaga gtatatattt
    34861 ttattgatag gatttgtatc tgtagtattt acatcaattc ttataaataa atctatttat
    34921 aaagtaagca ctttaataag ttttctattt ttagttttgg aaattttagt gtttataatt
    34981 tctatagaat ttattatacc ttatgaatac agtgatgtat ttactgttct atattcaagt
    35041 ataaacatat ttgtatgtag tcttatatct aataaacttt tgaagcaaaa gattgacttt
    35101 taggagggat attatgaaag caaaaaatat aggaaaatat acaatatgtt ttataatagt
    35161 atgtttttta atgattacta tgaccttaat attgagttat tttaataagg ataaactatc
    35221 tgtaaaaact ttaaaaggca atgtaaaaga tatagggaga gtaagtgtag tatatacacc
    35281 taatataagc aaattttctt atgaggaggt aattataagt aaaaatggag taagaaataa
    35341 taaaaacccc aaatcaagaa ttagaaatga ttatttaaat attgacaaaa aatacagtga
    35401 ttttgttaat gataaaggaa aagaacttat atataaagat gatttgaata taggagaagc
    35461 gtatacctct gttaagtctg atttagtaca aggaatgaat gctttaaatg attgtataaa
    35521 ggtttcaaat aaaaatttaa aaagtggggt agaagaaaat tttgatatta atttaaataa
    35581 gtctgatttt aaagaaaaca gttggaaaac cttgtttaat aaaatatata aaggcaattt
    35641 atatatggta attagtgaaa ctaatatttc aggttctaag gtcaataata tttgtatatt
    35701 aaagatagat ataaaaaata agtcttataa attattaaat agatttaatt taggattaca
    35761 gaatggatat caacaaaata tcaatgaaat taaattttct attggaagta aattatactt
    35821 agaaatagta aataataaaa gtaaaaatgg agatattgaa ggacatgata gttactctaa
    35881 ccttattata tatgatatag aagataacac ttttaatata agtaataaat ttatggataa
    35941 tctaaacaaa gaaaagaatg caaatccaaa ggagattggc ttattaagta aaactaagct
    36001 agattatatg ataaaaaata ataaattgaa tcttatagtt acggatatga gtaattccat
    36061 aatcaatctt gtttatgata ttaattctaa tgagattaaa ttagaagatt atgagatact
    36121 tgatttaaaa gtagattata atgaagcatc atctggagtt aggaaagtta agttactgga
    36181 tgataagatt tattctattt caggtatgaa gaacagtata tcaggagaat taaaaggatt
    36241 taaagggatt gttgatgtag tcggaactaa gccagtaaaa tttcaagtat ttgatatgaa
    36301 acttaaaaag aatatttatg aagctgagct aataaatgga gatataagtt tacaagaaaa
    36361 gttatttttt gttgcaaatt aagtattaga attaatttta gaactttaaa cttttatatg
    36421 tatcacagat aagtataagt aagggagtgt ctcaaaataa actttttagt tcatgagaca
    36481 ctttttttat atgaaatcaa atatattttc attgtttaga tttattttga taatgaaaaa
    36541 aagattatct ttattttaag aaagacattt atttataatt atatacaaaa atatttttta
    36601 atgtttttgt gtataattat aacaatttaa tttatattaa tgcacttaaa tttgaaatag
    36661 aatgcttata gtggtaaaat taattattag aatattagaa ataataaata aataatacat
    36721 tgtacttaaa agggggagaa atttaagatg aacaaaaaat atattaaagc agggaattta
    36781 attgatggaa caggaaatag tattatgcaa aataagggta taattattga tggagatact
    36841 atagttgaaa ttgaagatat aagagatgat ttaaatggat atgatgtgta cgattactta
    36901 gataaaactg ttatgccagg cattatgaat tgtcatgttc acttgacaat ggagccagtt
    36961 ggaaatccaa agatatatta tgataatgta tcagatgtag agcttgtagt aaatacgata
    37021 aaacaagttg atgcttattt ggattcagga gtaacatata ttagaagctt aggttgtccc
    37081 aaatatgtgg atgtacaact taaaaatctt atagacaaag ggtctataga tggtcctggt
    37141 atagttactt caggtccagt tatatgtatg acaggagggc atggatatta ttttggtatt
    37201 gaaagtgatg gagtggatga atgtagaaaa tcagccagaa cagttttaaa aaatggagta
    37261 gattgtgtaa agataatggc aactggaggt gtaacaactg atggagttga gccagggtca
    37321 ccacaattaa ctttggagga aatgaaggct gctgtagatg aagctataaa agcaggtaaa
    37381 ataactgcca cacatgcaca aggaagaact ggtataaaaa atgcagttct tgcaggaatt
    37441 acttctatag aacatggtgt ttatttagat gatgaaataa ttgatttgat gcttgaaaga
    37501 ggaacttact tagttccaac tgtggctgca ccatatttta ttctaaatgc aggaaaagaa
    37561 agtggaataa ctgaagctac tcttagaaag tgtgagattg ttgccattcc acataaagaa
    37621 tcattcctaa aagcatataa aaaaggaatt aaaattgcag ttggttctga tgcaggaact
    37681 tcttataatg aacatggaaa aacatattat gaaatgaagc taatgtcaga ttatggtatg
    37741 gataatatgg atataatagt tgctgctaca aaaacagcat ctgaactttt aagaattgat
    37801 aaaaattatg gaactctaga aaaaggaaag aaagcagatg ttatagttgt aaatggaaat
    37861 ccagtagaga atatagacgt acttgcagat gtgttagcag tatttaaact tggtaaaaaa
    37921 gttagataaa tagtataaaa ataaaaaaga gtgtctaaag aaatttttaa ataattatag
    37981 acactctttt ttattagtaa taattaaatc ttttatactt tagaaaatag attctatttt
    38041 atatttagat ataactcttt aaaatcattc ttatgcaata taatctatag aatctacaca
    38101 tacaaagtat attcttgaat cattagaatt tccaagtact ataacatcat ttttcttacc
    38161 tagaacttca acaccagtta gaaccaaact accagctact acagtaactt gattatttat
    38221 atttgacata taaagattat ctaggatacc tttattacaa cagcaatcat cacaatcgca
    38281 gttacaatta cattctttgt aatgtttttt atcaagatag taacctaaag atgctatgaa
    38341 atcttcataa tctgcaggtg taatatcaaa tgcaacagct ttaagattac acaatgatgc
    38401 taaatctacg tttgctaatg gagtagatgc agcaagtata aaatcaatta tagcagcaag
    38461 tattgcatct aatatagccc caaggtctat cgtaggagga ataactgcat caataagtgc
    38521 aattaattca gctactcctg gtatagttcc tatagtatta attaatccct caagagttaa
    38581 agggactgga ataggataag atactctacc agctatatct attaaatcac agttacaagc
    38641 agaaaatctt tcaaaagtac catcaagtcc agataaatta tcttttggag gagctgaaag
    38701 atctatacct accaaattag cacctactat aaagaaatct gagataaaag caaattgatt
    38761 aaagtttaca aaaggtctta gagcatcata tcttagaagt tctaaggcct ctctcatact
    38821 ttttttacaa caacattgtt ttattttagg ttctttatat ttatttggat aattatagta
    38881 tctatcagct acttgataat tttcatagta tctttcattt gtatttggat aatcttcctc
    38941 atattcttgt gtaaatctaa agtcctctct acatttatta ttttccacta aatacactcc
    39001 ttttatattt taatttaaat gtatagataa ttaagcttat ctatatagta atattatatt
    39061 tataatgtaa aaaaatgtta caaaagatat tataaacgaa taaaaaataa taatttgtca
    39121 gataaacttg taaattttta tgaataatcc attctaaaac aaaaaactgt gtataaaaaa
    39181 ggtttatatg ttatatttat ataaatataa catatgaacg agaaaggagt ggtttgataa
    39241 atgattgagg tagataaatt gtgtaagtct tttacaaggg ttgtaaaaga tgataagaat
    39301 aaaagttcaa taagaaagct aaagaaagta aaaactaaaa aagaagaatt ttttgctgta
    39361 aataatgttt catttaaagt tatggaaggt gaaattgttg gaatattagg tccaaatggt
    39421 gcaggaaaga ctacattact tagaatgtta ggtggcatat taacaccaac atcaggaagt
    39481 ataaatattt ctggatatga ttattcaata gatagaaatt cagcaaaaaa agaaataggt
    39541 tatctctctg gaaatacaaa actatatgga aggctttctc cgagagaact tctaacaact
    39601 tttgcaagtc tatatgagat gtcaaaagaa gatatagaag aatcaattga aaatattgta
    39661 aaaataatgg atatgagtga atttatagat aatagaattg aaaatctatc aactggtcag
    39721 actcaaagaa catctatagc ccgttgttta atacattctc caaaagtata tatttttgat
    39781 gagccaacac taggtctgga tgttttaagt agtgcatcta ttatagattt tatgaagaat
    39841 gaaaaactaa gaggaaaaac tgttctttac tcaactcatt atatggaaga agcagaaact
    39901 ttatgtgaca agatttttat gattcacaat gggaaaataa ttgcatcagg aacaccacag
    39961 agtttaaaag aggaatctgg agtaaataat ttgagagatg tattcataaa acttgccaga
    40021 aaggaggaca tttaaatgag aagtaagatt gtaaaataca tatttaaaaa agaaatgtta
    40081 gacatattga gagataaaaa gactttattt atgatgattg ttgtgccact tcttttatat
    40141 cctttactta tgttattaat gattcaagta atgaatatgt ctgcaagtag tatgaatagt
    40201 aaggacatta atatagcttt taataataaa cctaataagg tgttagtatc catgattgaa
    40261 gatgataatt tagaaaaaga tactaaaaat acttcaaatg ataaaggcaa aataagagtg
    40321 ttagatgtag ataactataa aaagtcatta gaagaaaata aaattgatgc ttatataaag
    40381 atggaagaaa aaaaatcatc tataaattat caaatatata taaattcttc tcaagaaaat
    40441 tcttctaatg cactaaaaag aattgaaact gttttggata aatataaaag atttaccata
    40501 gaaaaaactt tatctgaaaa aggattagat gtacaagcta ctttagaacc aataacatat
    40561 agcactgtag atgttgcaaa gacggaagaa gtggcaggat actttttagg tcagatactt
    40621 ccatttatat taataatagg agttttacta ggttcaatat atccagcaat agatgttatg
    40681 gctggagaaa aggaaagagg tacattagaa acattattta cactcccaat atcaaactta
    40741 gaactggtta tgggaaaata tatggcagtt tctcttagtg caatagtaac agcaatttta
    40801 aacattttat ctatgggact gactatggca tttattttag ttagtggagg tattagtagc
    40861 caatttggct ttggaaactt taattatgga gacttagtct taccaattat aactacttta
    40921 atttgcatat gtcttttttc aatggtagtt tcagcaataa gtatgtgtgt atgttcatta
    40981 gcaaaaagtt ttaaagatgc tcaaaactac ataacacctc ttatgttaat tattatgata
    41041 ccatcatatg tttctatgat accaaatata gtattggata gagtgacagc tgtaatacct
    41101 gtagtaaata tatctttact tataaaaagt gtattatctt ttaaaagcga tttaaattta
    41161 atagccttag ttttagcatc aaatgtagcc tttgttatat tggcaatcat actactgtct
    41221 aagatgttca attctgagga aatacttttt ggtaatagta agagtttttc tttcttagag
    41281 aaaagaagta atataaaaaa agggtctata ccaactgtaa gtgatggtgt tattttatat
    41341 gcagtaggat tagttctatt gatttatgtt ggttctttag ttcaaattaa atttggtatg
    41401 gcaggtatta taatgacaca attcatgata atttctttac cattattatt tgcatgctat
    41461 attaaagctg attttaaaga ggtatttagc ttgacagttc ctaaattaaa gcatgtgttt
    41521 gggagcattg ttctttggat tggtggatac atacttatta tgattataac acagctaatt
    41581 ttattcttat ttcctcaaaa tatggaagtt gctgaaagtt taaataaggc tctttttatc
    41641 aaagatagtg ttttactgaa tttactagca atagctttat taccagctat atgtgaagaa
    41701 ctgtttttta ggggatttat attttcttca tttagtaaat caaaagataa aaataagtct
    41761 atcaaactcg ctataatatg tagtggggta ctatttggta ttatgcatat ggattttatt
    41821 agaataattc caacatcaat attaggtatt atatttgcat acagtgtgta taaatctggt
    41881 tcaatatttg tatcaatgtt attgcatttt ttaaataata gtgtagcagt tgtgttaaat
    41941 cattatacaa ctggaaatat aaccaactta tataaatttg ttgaagttga tttttcgaac
    42001 ttaaatgtac ttaaatttgc cttaattctt ctaataagtc ttatattaat tatgttagga
    42061 ttaagagttt tagatagaaa gtctttaaga aattaagtat aaagttatta tatagattaa
    42121 aatattaata agcactaaag tatatggata tatcttgtat ataaaaatac tttagtgcta
    42181 ttttatatat tttaattata tgaattattt atcgtt
//
LOCUS       DAEQJM010000029        41616 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.029, whole genome shotgun sequence.
ACCESSION   DAEQJM010000029 DAEQJM010000000
VERSION     DAEQJM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41616
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.029"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            477..1457
                     /locus_tag="KRQ43_001936"
     CDS             477..1457
                     /locus_tag="KRQ43_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH2742292.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGVILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
     gene            complement(1556..2518)
                     /locus_tag="KRQ43_001937"
     CDS             complement(1556..2518)
                     /locus_tag="KRQ43_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH2742293.1"
                     /translation="MNKSWSNLIIKNKDKKVRSGWIIITVMAAFYIFEYYLSTILMEI
                     IRKILIATGDINLKTNYFSEYANWLNDVGLQVVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(2838..3788)
                     /gene="hpdA"
                     /locus_tag="KRQ43_001938"
     CDS             complement(2838..3788)
                     /gene="hpdA"
                     /locus_tag="KRQ43_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HBH2742294.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFKDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSAENISDIISFMHKNNLIEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDIDEEHLEELQDIFLDNGIACYVGHETAF"
     gene            complement(3781..4038)
                     /gene="hpdC"
                     /locus_tag="KRQ43_001939"
     CDS             complement(3781..4038)
                     /gene="hpdC"
                     /locus_tag="KRQ43_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HBH2742295.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDSACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            complement(4042..6750)
                     /gene="hpdB"
                     /locus_tag="KRQ43_001940"
     CDS             complement(4042..6750)
                     /gene="hpdB"
                     /locus_tag="KRQ43_001940"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HBH2742296.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDHRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            complement(7047..8063)
                     /gene="tsaD"
                     /locus_tag="KRQ43_001941"
     CDS             complement(7047..8063)
                     /gene="tsaD"
                     /locus_tag="KRQ43_001941"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBH2742297.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSNKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            complement(8069..8545)
                     /gene="rimI"
                     /locus_tag="KRQ43_001942"
     CDS             complement(8069..8545)
                     /gene="rimI"
                     /locus_tag="KRQ43_001942"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBH2742298.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKCIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            complement(8535..9251)
                     /gene="tsaB"
                     /locus_tag="KRQ43_001943"
     CDS             complement(8535..9251)
                     /gene="tsaB"
                     /locus_tag="KRQ43_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBH2742299.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            complement(9251..9703)
                     /gene="tsaE"
                     /locus_tag="KRQ43_001944"
     CDS             complement(9251..9703)
                     /gene="tsaE"
                     /locus_tag="KRQ43_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBH2742300.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            complement(9842..10882)
                     /locus_tag="KRQ43_001945"
     CDS             complement(9842..10882)
                     /locus_tag="KRQ43_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH2742301.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWEDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            complement(11211..11816)
                     /locus_tag="KRQ43_001946"
     CDS             complement(11211..11816)
                     /locus_tag="KRQ43_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH2742302.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     regulatory      complement(11941..12058)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(12118..13284)
                     /locus_tag="KRQ43_001947"
     CDS             complement(12118..13284)
                     /locus_tag="KRQ43_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2742303.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     gene            complement(13432..15573)
                     /locus_tag="KRQ43_001948"
     CDS             complement(13432..15573)
                     /locus_tag="KRQ43_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBH2742304.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYNEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            complement(15717..16824)
                     /gene="prfB"
                     /locus_tag="KRQ43_001949"
     CDS             complement(join(15717..16748,16750..16824))
                     /gene="prfB"
                     /locus_tag="KRQ43_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBH2742305.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            complement(16839..19514)
                     /gene="secA"
                     /locus_tag="KRQ43_001950"
     CDS             complement(16839..19514)
                     /gene="secA"
                     /locus_tag="KRQ43_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH2742306.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMVREDLPDSVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            complement(19646..20197)
                     /gene="raiA"
                     /locus_tag="KRQ43_001951"
     CDS             complement(19646..20197)
                     /gene="raiA"
                     /locus_tag="KRQ43_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH2742307.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDSEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            complement(20750..21424)
                     /locus_tag="KRQ43_001952"
     CDS             complement(20750..21424)
                     /locus_tag="KRQ43_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBH2742308.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDIGVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            complement(21427..22479)
                     /locus_tag="KRQ43_001953"
     CDS             complement(21427..22479)
                     /locus_tag="KRQ43_001953"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBH2742309.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISKKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKTPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSNTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            complement(22527..23486)
                     /locus_tag="KRQ43_001954"
     CDS             complement(22527..23486)
                     /locus_tag="KRQ43_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HBH2742310.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIVDFTFSVV
                     TKEESPAVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            complement(23582..24100)
                     /locus_tag="KRQ43_001955"
     CDS             complement(23582..24100)
                     /locus_tag="KRQ43_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBH2742311.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNEKEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            complement(24111..25445)
                     /gene="celB"
                     /locus_tag="KRQ43_001956"
     CDS             complement(24111..25445)
                     /gene="celB"
                     /locus_tag="KRQ43_001956"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBH2742312.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLISSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIVTPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            complement(25484..25810)
                     /locus_tag="KRQ43_001957"
     CDS             complement(25484..25810)
                     /locus_tag="KRQ43_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742313.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            complement(25835..26143)
                     /locus_tag="KRQ43_001958"
     CDS             complement(25835..26143)
                     /locus_tag="KRQ43_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH2742314.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            complement(26284..28197)
                     /locus_tag="KRQ43_001959"
     CDS             complement(26284..28197)
                     /locus_tag="KRQ43_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH2742315.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNVSTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            complement(28529..29311)
                     /locus_tag="KRQ43_001960"
     CDS             complement(28529..29311)
                     /locus_tag="KRQ43_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBH2742316.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            complement(29314..31533)
                     /locus_tag="KRQ43_001961"
     CDS             complement(29314..31533)
                     /locus_tag="KRQ43_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBH2742317.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            complement(31797..32894)
                     /locus_tag="KRQ43_001962"
     CDS             complement(31797..32894)
                     /locus_tag="KRQ43_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742318.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSNIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            complement(33210..34403)
                     /locus_tag="KRQ43_001963"
     CDS             complement(33210..34403)
                     /locus_tag="KRQ43_001963"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBH2742319.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     regulatory      complement(34540..34643)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            34832..35341
                     /gene="yyaC"
                     /locus_tag="KRQ43_001964"
     CDS             34832..35341
                     /gene="yyaC"
                     /locus_tag="KRQ43_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBH2742320.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     gene            complement(35452..35880)
                     /gene="fabZ"
                     /locus_tag="KRQ43_001965"
     CDS             complement(35452..35880)
                     /gene="fabZ"
                     /locus_tag="KRQ43_001965"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBH2742321.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEIEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(35896..36915)
                     /locus_tag="KRQ43_001966"
     CDS             complement(35896..36915)
                     /locus_tag="KRQ43_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH2742322.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            complement(37112..37372)
                     /gene="spoIIID"
                     /locus_tag="KRQ43_001967"
     CDS             complement(37112..37372)
                     /gene="spoIIID"
                     /locus_tag="KRQ43_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HBH2742323.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            complement(37470..38138)
                     /locus_tag="KRQ43_001968"
     CDS             complement(37470..38138)
                     /locus_tag="KRQ43_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HBH2742324.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFNDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            complement(38204..39268)
                     /gene="spoIID"
                     /locus_tag="KRQ43_001969"
     CDS             complement(38204..39268)
                     /gene="spoIID"
                     /locus_tag="KRQ43_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HBH2742325.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKSTVSYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            complement(39355..40608)
                     /gene="murA"
                     /locus_tag="KRQ43_001970"
     CDS             complement(39355..40608)
                     /gene="murA"
                     /locus_tag="KRQ43_001970"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBH2742326.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            complement(40629..41366)
                     /locus_tag="KRQ43_001971"
     CDS             complement(40629..41366)
                     /locus_tag="KRQ43_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HBH2742327.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
BASE COUNT        12717 a         7702 c         4330 g        16867 t
ORIGIN      
        1 aaaaatcaac gttatattat aatcatatag taaattaaaa tcatttgatt tatttaatta
       61 ttatttatta accagacgaa tgtaataatt attaaatata caatattaaa atcaaagaga
      121 ataataaatg taatattaaa actcaataat aaatttatat tcataagttt aatttcttca
      181 ttaattttat caactatgcc tctactgcct attaatttaa tgcaataaat aataaatctt
      241 ttacaaaaag ataataaaaa tatagaaaaa tattttttat tgtccttttg cttatggtaa
      301 accacattct gcctgcaata taactaaata tatgggtata tagtaaaatt aattttatta
      361 tttatatata attttataag ttacttttca ataatattga ctgtcatgaa tttataatat
      421 tcaataaaat attttaattt agttaagaat ctatattgta aaggagtatt aaattaatga
      481 acttaaaatt aatatggata aatattctaa acccagtatt tattaaaaat gaaataaaaa
      541 gaaaaaaaat acaaattatt atctttttct ttataaactt tggtttaact tattcattag
      601 gtttactgtt atattataat aaatttattg atccagaaaa ctttgcatca ttcatgatga
      661 tattacctct atcttcagtt gctattgcaa agttttatac tgaaggatta aataatgata
      721 tgtatgaatt ttattcacta atcatattat tttttcttat ttattcatta ttaattgttc
      781 ttaagttatt aaatctaata aataataatg aatttataat tataaaccta atattaactt
      841 ttataagtag cttatcaatt ataatatatt catcaaataa aaaaaattta tatcctgtaa
      901 aaaatattaa actaggttct ttattaatta tttactttat gatttctgta attgttccaa
      961 catcatttat actaatacta caaggggctc aacctaatta tagtggtatc ataaaattta
     1021 tatttactcc aataacatca ttaactacta tttatatttt ttttagtgaa gaatatgcct
     1081 ggagaggttt tttacagaat attttttttg ataaatttgg taaaaaatta ggagtcataa
     1141 tattaggtat gtgttggagc ttgtggcact taccactaat atttacatta tatacacctg
     1201 aagcgccaat attaggagta atattacgtt caatacatat agttggaatt tcaatatttt
     1261 taggatatct ttatataaaa actaagaata tctggttttg tgctataatt catgttttaa
     1321 ataatagtgc ttttcttatc acaaattcta aagaatcaac tatcacttac catgatatac
     1381 taatagtatc tatggttgtt ttaatttttt atgttccatt tctatttaca aaagaatata
     1441 aaaataactt ggagtaaata gaatatccaa gttattttta tatttttgta aatttccaac
     1501 aatcctacag aatactttaa gtttagaaga tattattaaa atttattata atcaactaat
     1561 tcttgatatt agtcacattt actttatcac taacaaaatc atacttagaa tctctatagt
     1621 aataccatac aaatataaag ctaagtagat taacaaaagt agtcaaaatt ccaccttcaa
     1681 taccaaacat ccctccattt aatagattac catgagtgat ttgtgtagtt ataatccctg
     1741 gaacctgaag tccacttaca ggcataccat atataatccc ctgaaataca ttccatgtaa
     1801 aatgataacc tatacacatc catatattcg acgactttat aaacatatat gaaaaaagaa
     1861 tcccaataat tataatatta attacagaca aaaaagtaac atcaggattc catatatgaa
     1921 tcaacccaaa aataacagat ggaacaatca ttataaaata aatattttta catcttcgta
     1981 aaactgccat aaaaaaacca cgatttaaaa tttcttctgc aaaagcaact aaaataaaga
     2041 caagtatcca agaaactgtt aaaggtgaaa tttttggtac ccatgaagta acatgaccac
     2101 caccaattgt tattgttata ataaagatta ctgtacaatt aaatattcct aataacattc
     2161 ctacatatcc ttcttttttc ttaattctat aagaatgtaa tcccatttca ctaataggat
     2221 ttttcataat aaatctccat acaattatag gaataataat cataagtgaa tctgttagaa
     2281 tttgaaatac aacctgtaac ccaacgtcat ttaaccaatt agcatattcc gaaaaatagt
     2341 ttgtttttaa attaatgtca cctgtagcaa tcagaatttt tcttattatt tccataagta
     2401 tagtgcttaa ataatactca aatatgtaaa aggcagccat aacagttata ataatccacc
     2461 ctgaacgtac ttttttgtct ttattcttaa taatcaagtt actccatgat ttgttcatat
     2521 agatgtcttc ctcctaacta ttatttttag ttgtttctaa aatatattct attaaatttc
     2581 ttcatagtag tattttacca caaaacttct gcttcaataa agtaaacgta atatattctc
     2641 taactgtaat ttaaactata aaaaatatat aaagtataaa tttaaagtaa tatttatgga
     2701 cataaagcaa tatgaacaat atataaaaca tataaaactt tacttaatta tttctacata
     2761 aaaaccacat aaaaaaggat gtaactctag cttttagtgt aacatccttt tttaattaaa
     2821 aaaacttgta tttgatttta aaaagctgtc tcatgaccaa catagcaagc tataccatta
     2881 tccaaaaata tatcttgtaa ttcttcaaga tgctcttcat caatatctcc cttatcagaa
     2941 tactcatact ccttacctaa ttgaatccac tttgattctc ctagcctatg aaatggtaat
     3001 aagttaatct ctattaaatt atttttgtgc ataaaagata taatatcact tatattttca
     3061 gcactatcat taaacccaga gataactggt actctaagta ctaaccttcc attccagtca
     3121 gaatttgcaa ggtttgatat attttctaat attaaatcat tatatacacc tgtttgttct
     3181 ttgtgttttt ctctatccat atgctttata tcaataaatg caaaatcaat atctttaaat
     3241 attttattaa aaacttcatt tgatacacat gcacttgttt caatggcagt gtgtatattt
     3301 acctcatgac actttaataa tacttcatgt aaaaattcat gctgaagtag tggctcacct
     3361 ccactaaatg ttactcctcc attacttctc caattgttag aatcacgttt aattacctgc
     3421 acaagttcat ctacagtata aggttttgca cataatttaa acgcattata ataacatgag
     3481 ttgacgcatt caaaactttc acagtcctta cagatgttcc aatctataac tggcttatta
     3541 tcaagattaa agctcaatgc accattttta cacttaccat gacatacagt acatccattt
     3601 tcatattgac aagataattc actaaacatc atatgtggtc ttacagtcca actttctgga
     3661 tttgcacacc atttacaact cagtggacat ccatttaaaa atacagttgt tctacaacct
     3721 ggaccatcat gaactgaaaa gctttgtaca tcgaaaatca tgccttctaa ttgcttttga
     3781 ctactcatta aacacatgtc cttcacaagt aattgcattc aatgttgaat atacccagtc
     3841 ttctttctct aggccaacac atttgcctat accttcatca ttagcttcaa caaaattttt
     3901 acaattttta cattttggca ttacttttat ctctggacat gctgaatcat ctaaattaat
     3961 catttgtttt gataatctac aaattccttt ggttgcatct actgcacaaa aattcataca
     4021 atcactatgc tttctcatat tttacacccc ttcatactct gttctagcaa ttacttcatc
     4081 ttgtattggt ttacctaatt cacaccaata ttgagtaaac ccagcaacac gtaccattaa
     4141 ttgacgataa ttgtcaggat ttttttgtgc atcttttaat gtttctgaat ctacaacatt
     4201 atattgaata tggaacccac cttttcttaa ataacttctt gttaaatcta ataatttttt
     4261 agttccttgt tgtcctttta tagtagttgg atgaagtttt aaattcatct gagaattttg
     4321 aactactgct tggtcccaaa tagttgcaga ttcaaataat gcatatactc catttttatc
     4381 tgttcctgca tatgcagaga ctgaaccatc tgaatatgtt gttccactta gtctaccatc
     4441 tggagtagcc aaggtagcag ctccctgtgg tccatgtgta gaaacagata tttggcaagg
     4501 gtacatcttc ttagcatata aagattgtgc ttcttcacat acttttgata accatacctc
     4561 atagttttta agaatattat ctgcatacaa atcattattt ccatatttag gtgcatcaag
     4621 acaggccttg taaatagcat catatttacc agtcttatct acttttactt ggtctgccat
     4681 agaataattt cctacttcta atgcatcttt aaatccaaaa ttatttaata ttgcatcctt
     4741 catttcctct attgtaaatg ctttgtcatc atatacaagt ttcttaagtg ctgcaaatga
     4801 attgaccata gtaacagtac cacaagtttc tacgtttaat gttgcattat aacgatatcc
     4861 catatttcct atatgttgac ctttgtctaa acagtctggc tttagtagtg aatttattat
     4921 agaagtatca aattttctcc atatatctaa ctcaatgtta tttgctcttt ctaaaacatt
     4981 tattgcttgt ttataataat ctttaaatac ttctatgact tcttcataag tatctaatgg
     5041 cttattatga ggctcaaata cttgtatatt catacgatgg tctttaccat tcataagaac
     5101 aagttctaaa attttgggat tagctataaa gtgaactcca gagccagcag attgacctgc
     5161 tccacctgca atagagtacg tttttccgtt taaagttaac tgtttccaac accctggaga
     5221 cgtttccaaa catccaccta atgcaaatgc tcttgcttct tcaacagtca taccttcatc
     5281 agcaaattgt ttcatcataa atgttgttcc atttgagttg tttacccagg ctggataacc
     5341 agaaccaagc tttgtacatt cagcagcttt cattaagaaa tcttctggaa gcttttcatc
     5401 atatagcata gttaaactag gttgaggagt tctacatctc atacttgctt ctaataataa
     5461 ctcttctagt tcattagctc ctgtagaacc atcttctttt aatccaccta tagataaagt
     5521 attaaatgta ttacctgata gtactcctcc atttacgccc gctgaagcaa aacagtcaat
     5581 acaagtgatt tttattctat aaagctctaa taattcgata acctcttctt ttgtaattag
     5641 tcctttttct atatcttgtt cataccaagg atataaaatt tgaccaaaac gtcctataga
     5701 cataccagat atagcatcct catttactga tgctatatga attgtataag tcaactgaag
     5761 agcttcccta aatgtacgag gttgtttatg tgcaatatgt tctaatatct ccactaaatc
     5821 tgagtattct tttttagctt ctaaatctgt ctctatactt tctaaatatt ttgcatgttt
     5881 tgcataattt aaaatccaag tttgtaatcc ttcaataact tgaataacag cctcataaaa
     5941 atatagacgg tccataccaa taagcccatc tccagatgca tttcctgcaa ctgccttttt
     6001 acattctttt gccatttcta taattccatc taatccataa tttaaaggat aaaaataatt
     6061 tataacttct ctaccttgag gaagtgtata ccctgaatca aacatgcata taagtgtact
     6121 cattaggttt tcttttaaat cataatctgg catcattttt tcatagtgaa aacctaaatc
     6181 ttcaacagac tttccaaccc attcctttgc catttttaca agtacaggta cttcttcttt
     6241 tctcattccg aatttaccag ctattgaaac gacatttcca aaactttcag taacatttcc
     6301 tccaccagac ccaaattttg taagttcatc agctgtgtta ctggctaatt tctttgcctc
     6361 ttctctcatt tgttctcctt gagcaacaaa gaaactttca cttacccatg gcattggaaa
     6421 agaacctcta taatggcgtg tcttttgcat tactattttc tcaccaggta ttatatttgg
     6481 tgtcatatgt gaaaaagcag ctttaagagc tttagctctt ctaactactg gtatatcacc
     6541 atctgatttt ctatattctc tattatacca atatggaaat tccatatcag cagtagataa
     6601 tgtattataa tatacatcta ataagtcttc tgctctttta cttgcttttt tttcattaaa
     6661 ttcacttaaa ttttctttat tttgaaaatt tgatttaata ttttttgctt ccaaaatact
     6721 tcttattttg tcttctttac tttgactcat ttcttcccct ccttaatctt tctataatta
     6781 gtataaaact ttttaagaat gaaaaaaaag ggtatattac ccacttttta aaataatctt
     6841 tctatagaaa aaattaaact tgaagcaaat ctaagccaaa gacaatctgt atatcctaaa
     6901 atttgttgca attcattgga atataaagat tataaatagt tttacttcaa gttttaatat
     6961 atactatatt tatttttatt atatttaatt tcacttctac ttactttttt gaaacaatac
     7021 ttttatattt acaaattcat ctaactctac tgatttatct ttaaatttgg aactgcattt
     7081 aaactcatat catgcgtttt cccatttata aaattataat atcctgcaca ccctatcata
     7141 gctgcattat ctgtgcataa aattagagga ggatacttaa cagtaatacc attgtcttta
     7201 gcaagctctg ttattttagc tctaagcccc gaattagaag caaccccacc agaaagagtt
     7261 atgatattgt atcctttgtc ttttactgct tttagtgctt tattagataa aacctctact
     7321 acagcctctt ggaaagatgc tgctacatct tcaactacta tttcttcatt tttcattctt
     7381 tttccattta gataatttaa tacagaagat tttaatccac taaaactaaa atcatagcta
     7441 tcttcttcta aataggctct tggaaattct atagcatgtt tatttccatt cttggccaga
     7501 ttatcaataa taggacctcc tggatagcct aaattcatag ctcttgaaat cttatcaaat
     7561 gcttctccag atgcatcatc tcttgttttt cctaaaattt catacttgcc ataatctttt
     7621 acttcaacca agtgagtatg acctccagat actattaatg ttataaaagg aggttttaaa
     7681 tccttatgct ctatatagtt tgcacttaga tgcccttcta tatgatttac tcctacaagt
     7741 ggaatattca aagtatatgc aagtgcttta gcataagata gaccaaccaa taaagcacct
     7801 actagcccag gtccatatgt aactgcgata tggtctatat cattaaaacc tatatttgct
     7861 ttgtctaaag cttcttgaac aactatatca atattttcca catgttttct tgaggccact
     7921 tctggaacta caccaccaaa ttttttatgt gtctcgattt gagtagagat tatgtttgaa
     7981 agtacttctc taccattttt taaaactgat gcagctgttt cgtcacaact actctctata
     8041 gctaatgtta ttatatcact cataaactct acacctcttt taattggttc cacattataa
     8101 ttgcatcttc tttattatca ctgtagtatt cttttcttat tccacccatt ttaaatccat
     8161 attttctata taaattttgt gctattttat ttgatgctct aacttctaat gtcatagatg
     8221 caatattatt atctttacat aaatcaacta tgcattttat caacttgtcc cctatttttt
     8281 tccctctata gtcactatga acagccacat tatttatatg cccttcatca agtataagcc
     8341 aaattcccac atatccgaca atttttccat ttaacttagc tactatatac cttgctactt
     8401 cattagacaa ctcttttcta aaagactctt ttgaccaata atcttcaaaa caattttttt
     8461 ctacttcaaa aacttcatct atatcttctg tagtcatttc ttctattttt atatcatcta
     8521 ctattagttt tgtattatct tccattattt agcctcttca ttttttcatc atattgtact
     8581 tcagcttgag attttctgat atacatagga tttatcgtat aacaagtatg tacatctata
     8641 tttttattat atttatttaa tgctaaagag cataagcttc ctgcgttaga tacattatta
     8701 gctggtgaag gtatttttat attttttata ttctctaact tgtctttata tttgtataca
     8761 gcttctccaa ctattataaa ttcttcatta gttgatacaa tttcatctac taaagcatca
     8821 aactctacaa catcaacacc atctaattct atcatctctc cattttcaaa cttgtattta
     8881 gctgaataaa cttgattttt ctgcgcatct aatatacaac atatctttct atcacagaaa
     8941 tttatgttat ttgctagaga ttccaaagaa tttactgcta ttattggtat attatttaca
     9001 tgggccatag cttttactgt agccatacct attctaagtc ctgtaaacga acctggacct
     9061 atacatacag ctaataaatc catatctttt atacttaaat cactcatact caacatattt
     9121 tctatcattg gcataagctt ttgtgaatga gtttttttgt tgtttactgt aaactcacat
     9181 attaagttat catcttcaac aactgctaca cttgctgcca tagaagacgt atccatacct
     9241 agtattttca ttatttaatc aactcctcaa ctatctcttt ataaaactct ccttttggag
     9301 ttaatatcat ttctcttcct tcatctttat atctcaattc tatattcaaa tattcttttg
     9361 gaagtatatc ttctattaga ttagcccatt ctattataca gattccattt gaatttacat
     9421 attcatcata accaatatca tacatttcat cactactacc tattctataa acatcaaaat
     9481 gatacaaagg tatttttcct tcatattcat ttattatagt aaaagtagga cttgttatat
     9541 aatcttctat ccctaatgaa tctgccaagc tttgtgtcat tgtagtttta ccagctccta
     9601 aatctcctac taaacagata acactgcctt cttttaaaag tttacctaat ttatatccta
     9661 tttctctagt tttattttca ttttctaaat atatttttgc catcaattca tctccatttt
     9721 gatataatcg tcatgtgaat ttatatcact gcttaattaa ttatagtata agcctagatt
     9781 attataaagt acttgtcttt atcttttttt atctttcact attgatggct gtatctacac
     9841 cttatataca atcatcaata gcaattttta catactcttt tgctttatgg ttttgcttca
     9901 atgcttcttt acatattctc tcagattgct cttttacata cttaagagac ttatagttct
     9961 cttttactgc ttcaatacac attttttctg tttgattttt tatatacata agcatttttc
    10021 cattttgtct tacaatctct atacatatat cttctgtata cttatctatg taacttagta
    10081 catctttaat attatatttt ttatttaaat atcttatagc atttatacat atttcttctg
    10141 tcttattgtt gacaaattgt agacttcttc catcttgttt gacagcttct atacatattt
    10201 tatcagtttg tttatttaca tattgtaatg ccataccatt ttgtcttacg gattctatac
    10261 acattttttc cgtttgattt tttacatatt ttaatgcttt ataattttgc ttaatggcct
    10321 ctatacataa ttcttcactc tgttctctaa cgtatgcaag acacctgcca tcttttttaa
    10381 ttgcttctaa acatatcctt cttgtttgag tctctaaagc ctttagtata cttacaacat
    10441 ctatattgga agaatgactt attgctttta taataagccc ttctgtttta tttcgtacat
    10501 acttaagtgc attacaatct ttttttatag cttcaagaca caagtattct gtttgttctt
    10561 ttacatattc aagtgcttta taattatact ttattgcctc taaacataat tcttcggttt
    10621 gattttttac atactctaat gccttgtaat tctgccttat tgctaaaata cacataccat
    10681 cagtttgatt ttctatattt tttaattcac gataatcgta ttttaccctt tccatatttt
    10741 caatatattc attagtgata tactttaaag aatctcctaa ttttgtatca taaataccaa
    10801 tatgaatatc ttcccaatta ctattaaaat aatacccttt atcatctaaa aataattttt
    10861 ttattttttt agataaatgc atgaatatac acccctatca ttattaaatt agttattatt
    10921 aaaagtttga ttattagtct ttatagtttt ttaataataa ctttattttt tgtttattat
    10981 aaattcgctc tgtatattgt agataccttt ttcatatttt aatagttaat cgttttaatt
    11041 cttcctttat tttaaaattt aaatttgtct aaatatttct tattttatat acattttttg
    11101 ataaattaat aaagccataa tatatttaat atatcaatca caatatagga ctgaagttat
    11161 aaataaatta tggctattca atacatttaa ttttatattt tcttgtctaa ttatttcttt
    11221 attatatttc ccattttttt ataaagtggc aatgttacta aagatattat aacagccttc
    11281 agcacattaa atggagctat catccaaatt acaaaagtga ataaatcatg aacttgagga
    11341 tttatagctg aacctaaacc tattatagca tctagtccca taagttgacc ataaagtggc
    11401 aacattacaa aataatttac taatgaacca attatagtca tagatattgt tcctaataca
    11461 aaaccaatca gtacaccttt taaatctcca cttctcttat atgaataaca aagtatcatt
    11521 acataagaac caccaattaa tatatttgca aattctccta ttcctccagt tgttgttgct
    11581 gttattgctt gtaacacatt ttttactaca actattccaa atccaactaa tggtcctaga
    11641 gacattcctc cgaatattgc tggaatatct gataagtcaa tttttaagaa atctggaaat
    11701 atacctggta ttggtgcttg aataaacatt aataaataag atattgcaga taaaattgac
    11761 attactacta aagttcttgt tgaaatcata ttgcctcttt ttgctgtgtt ttgcataatt
    11821 attttccccc taatcaatat gtttatattt tttaggaaaa acaaaaaact cgaagaccct
    11881 atcttcgagt ttttatggat atagtttaaa caaactaaaa taaacttatt tatcttccat
    11941 aaatatcttc tctcatccag actttactgt cggctttgga atctcaccaa atcaaccacc
    12001 taagtagttc gcgggctata ccgccggtag ggaatttcac cctgccccga agatcttctt
    12061 tgatttttta attttcctta cactcttata ttagttaatt ttttaataat tgtcaagtta
    12121 ttttttctca tacactactt tgccatttat tatagtgtaa agtacattac tttgaatctc
    12181 tagtggagaa ttatcccaaa ttactaggtc tgcatcttta ccaacttcta tagagcctac
    12241 tctatcttct attcctaaag tcttagctgg atttatcgta attgattcta ttgctttttc
    12301 ttctttcata ccatgtttta ctgcaatacc tgcacatatt ggaagatatt gaactggtat
    12361 tactggatgg tctgtcatta tacatacatc aagacctgca tttgaaagta ttcctgctgt
    12421 attaaatgtc aaatttctaa gctcaaattt agacctttct gacaaagatg gccctactat
    12481 tacaggaaac ccttcttcca ctaattcatc tacaataaga tgaccttctg tacaatggtc
    12541 taatgtaagc tttaaattaa attcttttgc aattcttatt gctgtaaaca tatcatctgc
    12601 tctatgagca tgtgccttaa aaggaatttc tcttcttaaa actggtatta aactttccat
    12661 ttttatatca tattcaggtt tttcacagtc ttcatcatca tgactctcat acatatcaat
    12721 atcctctaaa tattcttctg ctttttttag gttttctcta agtaaagcag ctatagccat
    12781 tctagtttga ggagatttat catcctgacc ataacagctc tttggatttt ctccaaaagc
    12841 aattttagat gcaactggat tttttattac cattttatca attctttttc cacatgtctt
    12901 tatagctata cattgaccac ccataacatt tgcacttcca ggggttgtac aaacagaagt
    12961 tattccacct tcaaaagctt ctttaaaagt tctatccatt ggattaattc catctatagg
    13021 atttaattgt ggtgttattg ggtcagtctc ttcatttcca tctgctcctt caaaccctat
    13081 accatcttcc cataaaccta agtgagtatg agcatctata aatccaggaa acacaagttt
    13141 attactagca tctattacct ctacatctaa aggagctatc aaatcttctc caatttctat
    13201 tatttttcct tcatctataa gtatatctcc atgaattatc ccatttgtta tggtatttat
    13261 tttaccattt tttataaaaa tcattcattt tcctcctgat tttcaagact atcgttctta
    13321 ttttaatata ttttcttact atatactttt acaaattttt aacatttata cactcgagta
    13381 atctcattta caaatataga atttaagtac tataaccata cataaactta tctatttttt
    13441 cattgataag gcaactcttt ttttgtttaa gtcaattcca atgactttta catctactat
    13501 atcacctact gtaacaatac tcatagggtc tttcacaaaa ctattactca tttctgattt
    13561 atgaactaat ccgtcatttt ttattccaat atctacaaat gcaccaaagt ctacaacatt
    13621 tcttattgta ccttttaaag tcataccctc ttgtatatct tcaattttta agacatcagt
    13681 tctaagtata ggttttatac cttcttctct tgggtctctt cctggttttt tgatttcagc
    13741 tatgatatct tttaacgtaa cttgtcctac ttccagtttt tcacttaatt ccctcaagcc
    13801 aatttctttt attttttcat ctatttcacc tatattctta ttctttacat catctaaaga
    13861 atatccaatt atctcaatca tttttttaca tatatcataa ctttcaggat gcacacctgt
    13921 attatctagt ggatttttac cctctaagat tctcataaat ccagcacatt gagtaaatgc
    13981 ttgaggtcct agtcttttta cttttttcaa ttgtgctctt gatgtaaaat ctccattttc
    14041 ttctctatat gctattatat tttttgctat agctttactt attcctgcaa catgttctag
    14101 tagggagtat gatgcggtat ttaaatctac tccaacacta tttacagaat cttcaacaac
    14161 tccatctagc acttcttcta atctcttttt gtttaaatca tgctgatatt gaccaacacc
    14221 aatactttta gggtctattt ttacaagctc tgctaatggg tcttgtaatc ttctagctat
    14281 agatatagct cctcttattg atacatttat atctggatgt tcctcatttg caagttcaga
    14341 tgctgaataa acagatgctc ctgcttcact aactatcaca tactgcactt cgctatctat
    14401 ttcttttatc atttctgata caaaagtttc tgattctcta gatgcagtac catttccaat
    14461 tgaaattata tctatatcgt atttttcaat caatcctttt aaaactttct ttgctccctc
    14521 tacatcattt tgagggtctg ttggatatac tgttgtataa tctagtagtt taccattttt
    14581 atctactaca gctattttac atccagttct aaatgcaggg tcaaatccca taactacttt
    14641 gtctttaact ggtggttgaa gcaataaact tttaacattc tttccaaata cacttatagc
    14701 tctttcttga gctatttctg ttaaatgatt tcttatttct ctttctattg atgggaaaat
    14761 taatctttta taagaatctt ctattgaact tacgatttct tctttatttt tgaaattttt
    14821 atcatttaca tattcgttta ttatgtaatt taaaacttta tcattattta tttctaactt
    14881 aacctttagg aagctttctt tttctcctct gtttattgcc aaaactctat gtggagccat
    14941 actttttact gcttcgttat aatcataata catatcataa accgatttct catcagtagc
    15001 acttttgcta actatcatac cttctcttaa agctaattct cttatatact ttctaatctt
    15061 agcatcatct gagactagtt ctgcaattat atctctagca ccttttagag catcttcaat
    15121 agaaagaact tctttctctt catcaagata attctttgcc tctatttcta tattatctaa
    15181 attattctct agtattgaca atgctaaatt ttctaatcct ttttcttttg ctattgttgc
    15241 tctagttctt ttcttttgtt tatatggagc atatatatct tctacttctt gtaatgtttt
    15301 tgctttttct atattttgtg ttatttcatc tgttaatttc ccttgttcat ctattagtct
    15361 aactacatca tcttttctac tttgaagatt tctcaaatac attaattttt cataaaattc
    15421 tcttagtgta acatcactca tttcgccagt catttctttt ctatatctag ctataaatgg
    15481 tattgtattt ccttcatcaa taagttttaa tgtattattt atttgttcat ctctaagatt
    15541 aaactctttt tttaagattt gatttatatc caatttattc actcctaatg ttagtttttc
    15601 ataagtataa caaaacagaa cgaaggctga gggttatcgt cctcagccta agtgctgtaa
    15661 gtgcatatta agcactaacc ttcttataca tatatcttaa ttacagtgca tatttattaa
    15721 actattttat tcatttttaa gtattcatta ataaacaagt ctatatttcc attcattaca
    15781 ctatctacat ttccaaactc agcatttgtt ctatggtcct taaccaattt atatggttga
    15841 aaaacatatg acctaatttg actaccccaa gttatttgtg agtatttgcc ttgtatatct
    15901 tctatttttt ccttttgctc taactctttt aattctatca atttcgccat taaaagtctc
    15961 atagctctgt ccttatttag atgctgagac ctttcatttt ggcactgaac tactacacca
    16021 gtagggatat gtgttattct aactgctgaa tcagtagtat ttacatgttg ccctccagct
    16081 ccagaagctc tatatgtgtc tatctttaaa tctgacggat taatttctac ttctatattt
    16141 tcatctaact ctggtgttac atctatagat gcaaatgaag tatgtctttt ccctgatggg
    16201 tcaaatggag atattctcac taatctatga actccttttt cactctttaa atacccataa
    16261 gcatttgttc cttctacaag aattgtagct gtctttatcc ctgcttcagg gtctgatatt
    16321 atatctaaaa gcttaacttt ataaccctta ctttctgacc atcttatata cattctcaaa
    16381 agcatttgag cccaatcttg agcatctaag ccaccagtac cagcatttat agataatata
    16441 gcattatttt tatcatactc tccatttaga agagtcttta ttttcatttc agataatttt
    16501 tcttccattg attctatgga cttttctata tctctttcta cagaatcatc atcttcttct
    16561 aaacctattt caattaatac ttctatatct tctaataagc tttttaagct ttcatattct
    16621 tctaatgtct cttttaaaga tttattttct tgaagtactc tttgagcgac ttcattatca
    16681 ttccaaaagt cttgttgatt catcttttct tcattaattt gtatattttt catcaatgaa
    16741 gctatgtcaa agagaaaccc tcaattcttc taaatttgaa gccatctgct ccatactatg
    16801 tctatactct tgtaacttta acatttaatc ctccgagatt atcttccaca acagttttta
    16861 tattttttac cacttccaca agggcataag tcatttcttc caaccttttc atctttttta
    16921 acagttttac ttgttggaag tgttccatct gatggagaag atagattttc aacatctaca
    16981 actgcttttc tttccactgg agtttctatt gttatattaa ataaatatct tacagtgtct
    17041 tctttgatat gtttattcat ttcatcaaac atatcaaaac cttccatttt ataagcaata
    17101 actgggtctt gctgacctac agcacgaaga ccaatacctt ggcgtaattg gtccatagca
    17161 tctatatggt ctatccaatg gttatcaaca gcttgaagta agattactct ctcaacttct
    17221 ctcattctct catagccaac ttgttcttct tttgaagtat atatcttcat agctatttca
    17281 taaacttttt ctgttatttc aactggatta agtttttcta tttctggtat ttctatgcta
    17341 ccttttggca agaacagatt atacatatgt tctttgaatc cttcttcatc aaatccttta
    17401 tcttgtgtat aaagagtaac tgcttcttct attatagaat gagtcattga ttgtatttgt
    17461 tcttgtaaat cttcaccttc taatacacgt tttctctctg catatattat ttctctttgt
    17521 ttattcataa catcatcata ttgaagtaca tgctttctta ttccaaagtt tttaccttcg
    17581 actttctttt gtgctccttc aatagactta gataatattc tatgttctat cggcatgtct
    17641 tcttcaagac ctattttatc tacaatacca gatattctat cactaccaaa caatctcata
    17701 aggtcatcat caagacctat atagaatctt gaactccctg ggtcaccttg acgaccagca
    17761 cgacctctca actggttatc tattcttcga gattcgtgtc tttctgtacc tattatagca
    17821 agtccacctg cttctacaac ttgtttttgt tcttcttgtg tttgttgctt aaacttttca
    17881 aatagttttt catactcttc tctagcttca aatagaattt cattaccttt tacaggtata
    17941 ccttctattg gagtatctac cctatttact atttcctctt taaatccatt tcttctcatt
    18001 tctctcttag ttaagaaatc tgggtttcca cctaaaacta tatctgtacc acggccagcc
    18061 atatttgtag ctattgtaac agcgcctaat ctaccagcct gtgctattat ctctgcctct
    18121 ttatcatgat gcttagcatt taatacttca tgtttaatgc cttttttctt taatatttgt
    18181 gataataatt ctgatttttc tatcgatact gtacctacaa gtattggctg attaacttta
    18241 tgtctttcaa ttatttcttg tgctacagca ttaaatttac ctatttcact tttgtataca
    18301 gaatctggta aatcttctct taccataagc ttattggtag gtacttggaa aacgtccatt
    18361 ttataaattg ctttaaactc ttcttcttct gtttttgctg taccagtcat accagaaagt
    18421 tttttataca ttctaaagta gttttggaat gttacagtag ctagtgtttt agattctctt
    18481 tgtattttaa gaccttcttt agcctctatt gcttgatgta aaccttctga atatcttcta
    18541 ccaaacataa gtctacctgt aaactcatct actattacta tttctccatc tttagcaaca
    18601 taatcaacat ctttcttcat tattacatgt gctcttaaag cttgatttat atgatggtat
    18661 aattctgtat gagatatatc tgttatatta tcaacattaa aatacacttc tgctttttgt
    18721 atacccgatg ctgttagaga tacagcctta tctttttctt ctaattcata atcatctggt
    18781 tttaaggtta aaacaaatgt gtttgcatct gaatataagt gagttgattt gtctccaggt
    18841 ccagatatga taagtggtgt tctagcctca tctattagta tagagtcaac ctcatccact
    18901 atagcataat ttaatcctct ttgaactctt tgctctttgt gtattaccat attgtccttt
    18961 agatagtcaa atccatattc attatttgta ccataagtta tatcacaatc atattgttct
    19021 tttctaactt ttggattttg accgtgtata ataacgccta cactcattcc taaaaactca
    19081 tagatttttg ccatttggtc tctatcacgt tttgcaaggt aatcatttac tgttacaaca
    19141 tgtacacctt ttccagtaag cgcattcaaa taaacaggag cagttgcaac caaagtttta
    19201 ccttcacctg ttttcatttc tgctattctt ccttgatgta gtactatacc tccaatcatt
    19261 tgaactctgt agtgtctaag tcctaacact ctcttagaaa cttctctaac tactgcaaaa
    19321 gcttctggaa gtatatcatc tatactttca ccatttgcta atctttcttt aaatatattt
    19381 gtcatatttt taagttccga gtctgccata gattcaaatt taggttctaa tgaatctatt
    19441 atatcaacag ttttattgaa cttttttaat tcttttttat ctgccatgtt gaataaatta
    19501 tccataaagc tcatatttta catctctcct cgttctttat tgtactatta ttcattttac
    19561 cataaaaact atacttttaa tattaattta aaaagctatc gataatttat ttatcgatag
    19621 ctaatatgat taaatctaaa ttgctttatt catgttctat tataccatat ccaccattat
    19681 tacgcttata aactactgct atttcatctg aatctatgtt cttgaacata taaaaatcat
    19741 gtcctattaa ttccatctgt aatacagctt cttcttcact cattggctta acactaaatt
    19801 tcttacgtct ttgaattact aattcttgat tttcatcccc ataatcctct tgttcatcag
    19861 ctagatttat ctctgaatct tggaatctta tactcttgtt gtctttatgt ttatcttgta
    19921 atctcttttt atattttttt aattgtttac ttaatttatc atatacaaca tctatagctg
    19981 tgtataaatt ttcctgcata tcttctgctc taattatagg accatttaca gtagctattg
    20041 ttacttctat tttttgtctt gcttttctcg cacttactgt aacttttaca tcagtgtctg
    20101 gatgaatgta attatctaac ttacttagtt tagtttcgat tttatttttt attgcatcag
    20161 ttaattcgat ttgttttcca gatataatta tgttcataaa tacatctccc ttcaattatg
    20221 tcagtataag aaaatttata ctttaataat atattctaca cgaactctca taatcctctt
    20281 tttattattt acttttatga ttttttctat tcaattgata gaattattta tcatttttag
    20341 ttacattgat acttatgtgg attaatatta ttacaaacac ctgtggataa tgtggataaa
    20401 actgttaata actcttgttt ttgtttattt aaagctattt ttactcctat ttctatccac
    20461 aaaaatctcc attaattgtt tattaatatg tgaattcatg tcataagatg gtaattttag
    20521 gaaattatgt gtattatatg ccaatatacc tttataattt tttaataact ataaaccctc
    20581 taaaacctcc ataatctatc ttttctttca ttatttatat ttaaaactac ttaaaagtta
    20641 taaagcatac tcaacaataa tttcatattt aatacctatt aacattcata tacccaaatt
    20701 ataattaact tactctcttt atttaaacta agtattttat attcatatac tatcttgaaa
    20761 ttatatttac gagttgttta agcttttgtc tatctatatc ttcaaaagga ctgttattta
    20821 ttctaatcgc tgtaccaaaa tgaaaattac ttgctttagt taattccttt atcttttcta
    20881 tattattaaa attaagacct cctcctaaaa gaatttttat gtgattagaa ctaagcatca
    20941 tattctttat catttgtatg ttatcaacta tacttccttt ccctcctgat gttaatatat
    21001 tcgtaatttt atcataatcc ttcaaaattt taacactatc tattgtattt gattcatcta
    21061 tggctctatg aaatgtaaca tcaagattat cacaacattt caataaaaca tttagatttt
    21121 tctcatctat attattgttt ttatccaata caccaaatac aactccatta gcaccaatct
    21181 ctttaaccac acctatatct ttttgcatta tacttatatc ttctttactg tatacaaaac
    21241 ttttcgcatg atgtcttatc attacgttca caggtatctt tacactgtta acaacacttt
    21301 ctataagacc aaaacttggt gtcaatccac cttcagttaa agcactaact aactctattc
    21361 tatctgcacc acaatcttct ataattttag cgtcttctac tgacattcct attatttcta
    21421 acataactac tcctttgcta attcatatat tgcatttgca aatatctttg catttaatat
    21481 tatatcttct atatccatgt attcatcagg attatgagct attccttttt gtcctggaaa
    21541 tgaaggtcca aacggaacta tatttggcat tacttttgca tacgtacctc cattagttgt
    21601 cacgggagtt ccatctaatg atgtaaccct ttcataagct agctgaagct ttttaacaag
    21661 attactctct ttatcaaaat atacaggatt aaaattagaa attacctcta tatcgatact
    21721 atttggaaaa ctagctttta tttcatctaa tacatctttc aatttataac taaaatcgta
    21781 ttttaccttt atatctaata tagtattact attttctata ttcagctctt tatatgtaac
    21841 aagcacattt tcagacatat tttctataaa acctaggtat acatcttctt cataattgat
    21901 tttacttttt attctaatct ttgccatgcc tttttcacca tatacaacag gatatttaca
    21961 atctggtgta aatcccataa taggtgtttt ttctttttct aaataatatg gtatatcttc
    22021 aaatccactt tcttcatttg taccaaatat tattctaact ctcttatcta attttaagtt
    22081 taattcttta atagcatata atccatataa ggcagacatt ataggtcctt tattgtctag
    22141 tactcctcgt ccataaattc ttccattagt ttcttctccc ttataaggct gatgcttcca
    22201 accatctcct tcatgtacaa catctacatg tccaattaca caaacataat catcactatc
    22261 tccatgctct gcataaccaa tataattatc caagtttcta accttaaatc ccaatttttt
    22321 tgatatttct aatgctttat taagtgcctc ccctactttt tcgccaaaag ggaagccatt
    22381 ttctgactcc cctttgacac taggtatttt tacaatatct ataatatcac ttaataaatc
    22441 ttcttttaac tcatctattt tattacttat gatattcata aaaatctcct tattataaaa
    22501 ctctatttta attatgtaac actactttac tcacttactt ctatcggtgc ttttattcta
    22561 gcctcatatg cttccatcca ctcatttgat ataaccttat gtatagtctt tccatctact
    22621 ctatttgaaa tatatacagc aggagattct tctttagtta ctactgaaaa agtgaaatca
    22681 actatatttg tagctactcc ccattcacct ttattattca tggcaactaa tgataaatca
    22741 ccagcttttc ctcttctttt gataagctgt ttatcaagtt catttactgc aatatcacat
    22801 gcttcttgtg gatgctttcc ttctttcata agcctaacta tctcataaga tatacatccc
    22861 ttcattaaat cttctcccaa accagtagct gtagctcctc ctatactact atcaacatag
    22921 aatcctgaac cagatagtgc agaatctcct attctacctc ttttcttcat aaacaatcca
    22981 cttgttgatg tagctgcaca catttttcca gttttgtcta aagatatcat accaacagta
    23041 tcatgaccag catatgggct taatcctttg tctaaagtct ctttttttct ctttttataa
    23101 tgtaacttcg ctctatcagt caacatattt tttctttcaa atccattttt atgagcataa
    23161 tcttcagcac ctattccaac taaaaaatta tttaccttct cataacttaa cttcctagct
    23221 atgctgacag gattagaata atctcttata ccagcaactg cgccaatatc taatgtgtta
    23281 ccatccataa atgcagcgtc aagttctacc tcacaatttt catttggaag tccaccatat
    23341 ccaaccgatt tatagaatgg atagtcttca actcttctta cagcaagctc tacagcatca
    23401 cctgcttcca tgcctttttc taaatgttct gatgcctcag ttattccttc tagggccatt
    23461 ctccatgtcg ctatcattcc ccacatgtta aaattcccct ccttaaatta tatagatttt
    23521 actaatgtat gcttattata aatagtataa tatttaaact tgctaataat taatactctt
    23581 attaataaca aaattcttct ttcatcaaag ttatatcttc tttattcgct attgcttttg
    23641 ccaatttaca tatgttattt aatgaatcat taagaccaat tccacctttt ttgggagtct
    23701 taactataca tatgtcattt ttatattcgt ttatcacatc tatattttct tctgacatag
    23761 ctgcaaaagc tggtatatct gttttatcat ttatattttt agacagtatt gctgacatct
    23821 tagaaaagtt ttcgtaatta aagcttggtc cacagattac tacatcaggg tttaattttt
    23881 ttaccatagc tatcatctta ctcgttactt ctttttcatt atttacaaaa aattcatccc
    23941 cacaaaataa ggtagctatt accttagatt catttaaaaa ttgctccatc attacacctg
    24001 gtcctaatgg gcttgatttt ccagcaggag gtatattact tttctctttt cctccagctc
    24061 cagcttgtat ttgatccaat atcataacta ttttcttcat aatcttcctc ctataatact
    24121 aaatcatcaa aagatatatc atcatcttcc tcttcaacag tttcattttc ttctctcaag
    24181 tattgcttat ctagcatttt tataaatggt atatacataa atattcctag tataagaagc
    24241 actaattgta agactgcacc ttgccatcct gttgttaaaa aaccagagaa tataattgga
    24301 gttgtccacg gtaactgaac tccatttgta agaggcacta atcctgctga catacagaag
    24361 taagctatta ttatatttat tgttggaact attgcaaatg gtatcaatag tattgggtta
    24421 agcattattg gtagaccaaa tatcaatggc tcatttatac caaatattcc tggtaaaatt
    24481 gatagttttc ccattgactt tatacgttta cttttacata ttaataacat agctatgact
    24541 aatgatagtg tactacctgc tccaccaaat gtcgcaaaca tatcttggaa ttgacctgtt
    24601 attatgtttg gtatttttga accagcctga aaagcagcta agttttcagc tgatagaatt
    24661 tttaatattg gattatacac agccccaaca acactacttc catttattcc aaagaaccag
    24721 aataaatgta agaatatata agcgattgcc atagcaccta aactatttcc taattttaat
    24781 aatggcattt gtaaaaactt aaatataaat tcatgtatac ttccatatgg tgtagcttca
    24841 aaagctatct taactaaaaa gaaaactacc ataactattg cacttggtat taatgctgca
    24901 aatgattttg atacggttgg aggaactcca tctggcattt tcaatgtcca tccttttttt
    24961 acaactgcag caaataattt tacagaggtt attgctgtta tcatacctac aaacattccc
    25021 ttagagccca tccaacctag tggtatacct gttaccatgt agactgattc tgttccttct
    25081 ggtgtatatg gtattacaaa cggtgttact ataaaaaagg caactattgc aactgcagct
    25141 gatgctattg gatctacatc tatttgcttt gcataagaat atccaattcc taaaactgca
    25201 agtaaagtca ttacttcaaa tgttgctaca gttggttgtt gcaattttac agcccaatct
    25261 ggaccaaaaa tttgacctac aaattcattc catcctttta taggaaaatt tgctactaat
    25321 aaaaataatg aacctattat taataatggt gatgatatta aaaaaccatc tctaattgca
    25381 attaataatt tatttttacc tattttttca gccaatggca taagtattct ttccaatcta
    25441 ttcatctatc caccctcatt tcctattatt ttttactata attctacgct tgtttagatt
    25501 ttattagctt tatagcaagt tttaatactt tttccccatt catagttcca taatcaactt
    25561 cattgattat atctataagt tttccttgag cttcaaactt tggttttaac tcctttagca
    25621 tgtatttaac ttgtggtcct aataatatac aatctggatt tttttcttca actattttgt
    25681 caatttctgc tatcggaaat gcctctactt ctattggtaa attgtgttca tctgctacct
    25741 tctgcatttt atctgcaagt aaacttgttg acataccaaa gctacaaaat aaatatactt
    25801 ttcttttcat tcttttaaat cccccttaat ttttttattt taatttttga atttcttttc
    25861 ttaacataat catttctttt ataaggtttc tctcactcat acaagtcatt aaatggtctt
    25921 gagagtgaat caataaaata gatatatctg atttatctcc cccagcttcc ttttgtataa
    25981 gttcagtttg tactttatgt gcttttaaaa tttcttcatt tgcattttca attaattcat
    26041 ctgctttttt aaaatcgttt tcctttgcat agtcaagtgc ttcataaagc atagattttg
    26101 catttccagc atgaattata atctttaaaa ctatttcttc cattttttcc tcctaaattg
    26161 cttctctact tttagattat ttatacctta caaacatata atatcttata aaaacaaaaa
    26221 aacatgcaca actttttcca tcacatggaa aattttgtgc ttatccatag ttcattatga
    26281 attttatata agaatatctt ttaccttttc aatgtcacat ttacttagaa tatctagcat
    26341 attttcatcc tctgttaaat tagatatttc tttaaataat tctctaaata cttttctatc
    26401 atcatctttt ttatatgcta ataaaagtat aatctttata tcctttccat ttctaatttt
    26461 tattggtgtt tttaaccttg caaaacataa aacagattgt tttatatatt tcatgtctcc
    26521 atgagggaat aatattcctt ttccaacatt ggttggatat gacttttctc ttgttataat
    26581 agattgtaaa tactcttttt ctgcataatg tttttcaatt aataaattag ttaaatatgt
    26641 tatagcttca taaatatcat catgttctaa ctctcttatt aaataatcag acatcattaa
    26701 tctgttcata agtttatatg aggtgtcttt ttcttttatt ttgtttgtaa actctttaag
    26761 tttattctca tcctcatcag taaataatgg tgttgttata aaaattggtt tttggatatt
    26821 ttcatactct tgaaatgcaa ttataaaatc tatagtctta ttaaagttat ctctttttaa
    26881 atcttcctct cttaatgttt caataatttt tatgttatca aatctctttt ctatctttac
    26941 ttttaatagc atacttactc caaaactaaa tggacataca atacttgcct ttttatttga
    27001 ttcccttttg ctgtattttc tttctagaga ggtttgaaag tgaagtgtaa gataaccaat
    27061 ttcatcttcc gttatttgtt ttccttttaa ttcaatttct attgaacttg atattactgt
    27121 aaataaaaaa caaaatttag tttttatgtt atctaaaagt ggattttcta agtaaacatt
    27181 gcttttcatt tgatgcattg taacattcaa atgacatatt aattgttcat aaagtaatat
    27241 atcattatta aaatttattc ctgattcttc tgatactaaa tttataattt tttttgtata
    27301 acttgctaat tcttcattta gatataaaga tttcttaata ttattactat ttatttgttt
    27361 gttcataccc aatattaaag attctataaa caatttttct tcataattta atactatgga
    27421 taaattagat ttcaattcat cttctatatc caatataagc atttttagct taagctcttt
    27481 cttagtattt gatactttta aagaatttcc cagccttatt cgtattatat ttataagcaa
    27541 aaatagcatc aattgcttga atgatatatc tgtaagtctt atatccatat cctcctctat
    27601 agtaagcatt atgtttttta caattattat atctactata tggaagtact ctatttcatc
    27661 tatgtttaat ctgtatttat ctatgtattt aaataagaat gatactaaca ttattcttat
    27721 gtctttctca tccccttcaa tatatatacc actgcctttt ttagtcgaga catttaaatt
    27781 ataattattt aatgctactg ataatttact tatttcttct ctgacaatat ttttatttat
    27841 gtacaactta ttagataaat catttaaagt aactttttta ttattacaaa gtagtaaatt
    27901 taatatctca acttgcttat gaagctcact atttactctt ttaacttcac ctcgcaactt
    27961 ctgatttacc agtattttgt ctgttccatc tccactaaat ttaattccaa tattaggttt
    28021 tcttttgata taagcattac aaaaagtaga taaccattca tcaatatatt tgcaatcatt
    28081 ccttattgtc ctttctgaac actcaaaatc attggcaatc ttattaacat ttataaactc
    28141 ttcttttaat agcaatgttg ttaataaatt ttcttgtctt ttattcaaac atatcacctc
    28201 tttatgactc aacctaaatt tattatatat aaaaaagagc tatacataaa ggtatgctag
    28261 ctctctttta atatgatatt tagctgacct ggtttttgac cccacactcg cctactggag
    28321 ggttcgcttg ggttcgccgc actactactc tctctcgatt ttattatcgg taggtcttac
    28381 ttctaagccg caccatgatc attaacccaa tttttagtgt taacttacgt ggatcccttt
    28441 gcctgcgact ggcttggact ttcaaccaca gacctaaata tcacttattc attttaatat
    28501 tttaaactaa aattgtcaat atataagatt attccataat ataattatca tttgcttttg
    28561 taagtagagt caatacaaaa accttattag cacctgataa ctttaaaagt ttagagattt
    28621 cgtttgttgt tagaccagta gtaaatatgt catctattaa aagtatattt ttattattta
    28681 ttaatttaac attttcttta acaacaaata cattttttaa ttcttctttt cgttctttct
    28741 tattcaattt atatagcatt cttgtatatt tttttctact tatgcaatct aataatggaa
    28801 tatttactat tttacttaaa ttaaatgcta ttttttgtgc ctgattaaaa cctcttttat
    28861 ttagcctttt tttatgaagt ggaacaaata atatataatc aaattttatg ttttctaaat
    28921 ataatttttc tttcattatt tgagctatat acttagccat aaaggttttt tggttatact
    28981 tcagccctaa caccatcttt tttgtcacat cattatattc aatacaagat attgatttat
    29041 caaaataaaa gtctttatta aaacaataac tacactcttc aataaattct ttttcaattg
    29101 aatgacgtat tattggtttt ccacacttca tgcaaccatc ttgtataaaa ttcatttctt
    29161 taaaacaact tttacatatt gaataagtat ttgttttctt tatggattta tcacaaatta
    29221 tgcaacttat attctcagga tatataaaat ccaaacattt attaatcata tttttaaaat
    29281 tcttaataaa attatcattg catattttca tatttattct atcaacaacc cttcttgttt
    29341 aaatttattt agcttatatc ctaaatttga atacctttga ttaactctat tattttttat
    29401 catatattca agatatttca catctccaac taatacaact aatttttttg ctcttgttac
    29461 tgctgtatat aataaattac ggctaagtaa cataggagga gcccacgcta ttggcaatac
    29521 tacaactgga aattcacttc cctggctttt atgtattgtt gtacaaaaac tatggtcaat
    29581 ttcatctaat tcatcatata ggtatgatac aattttagtc tggtcaaata atatataaat
    29641 agttttctta tctttatcta tgtgataaac atatcctata tctccattat agataccttc
    29701 tccactttct ttttggtctt ctgtttccca tttttttgta taattatttt ttacttgcat
    29761 taccttatcg ccaactctaa ataatctttt agaaaaactt tcttcaactt taaatttttc
    29821 ttttttgtta agatacttct gtaactctat attgagatta gtaactccca attcaccttt
    29881 tctcattgaa gataaaactt gtatatcttt taatttatca actttataaa atttaggtaa
    29941 tctttcatta accaatccta ttatttcatt taaaatttct tcattagttg attttcttat
    30001 aaaaaagaaa tctttacctt ttgtatttag ataaagtggt tctccattgt ttatcttatg
    30061 ggcatttaca attatcatac tttcttgcgc ttgtctaaat atttcattta atttaactac
    30121 atttataata ttagaattaa tcatatcctt aagtacattt ccagcaccta cagaaggtaa
    30181 ttggtcacta tctccaacta aaattactct tgttcctaac tttatagctc taagtaaatt
    30241 gtacattaag ataatgtcta ccattgatac ctcatcaaca attattacat ctgaatttat
    30301 tgggtcttct tcatccttaa aaaaagttaa atcatcatct gttgaaaatc ccatttctag
    30361 caacctatgt atagtttttg cttctttatt agaagtttca ctcattctct ttgctgctct
    30421 tcccgttgga gctgccaaag tcacactttt accattattt tcaaatatat ctatgatagc
    30481 attaatggta gttgttttac cagttcctgg tccaccagtt ataattaata ctccactatt
    30541 aacagattct ttgactgcta aaatttgttt ttctgctaac ttaattttct tatcttcttc
    30601 taaaacatta atctcgttat ctatatctat ttttaagtct tcaaattcat actgtgataa
    30661 ttttactatt tgactacata ctccattttc agctaaatag tatggcataa ggtatataag
    30721 attttcattg tttactttct ctatatgtat tttttgatta taaactagca tcattacaca
    30781 ctcttttatt atttctccat ttagctccaa taatttttcc gaatcttgta ttagaacatg
    30841 ctctggtaaa tatgtatgcc cattacttaa agatttattt aaagtgtata agattccctg
    30901 acaaattcta tctttagagt ttttatctat accaatttta cttgctatac tatcagctac
    30961 tttaaatcca attcctctta tatcttcagc aagttggtat gggtttttat ttataacttc
    31021 tattgcactg cttttatatt ttttatatat ttttaggcag taatttggtg ttattccaaa
    31081 aggagatagc tgtattatta tatttctcaa ttctctgtct tcttcataac tttttactat
    31141 ttgttttact tttttactcc ctataccttc tacttcttgt aatttttctg gtgaattttg
    31201 tatcacctct aacgtatcta caccaaactt atcaattatt ctttttgcca ttttttcacc
    31261 aataccatgt atcattccag aagataagta aacataaatt ccttctaagg atgatggcgt
    31321 tactggcata aaactattca cttcaaattg agtcccataa atcttatgat ttacccactt
    31381 tccttcaact tctatgcttt ctccaattgc caaagtaggc atacatccta caaccacaat
    31441 ttcatcattt tcatttacca ggtgagctat tgtataacca ttatcttcgt ttttaaagac
    31501 tatttcactt atcattcctt ctaatttttc catttttatc tcctaaaaat actaataatc
    31561 gctccattta aatgttagta taattttata tattaaaact atgataatcg tagaaaagtt
    31621 ttatattttt atacttaacg taatttccaa ctattataca ttttatcaga aacaaaaaaa
    31681 atctgcatcc ataaaatatg gtaccatgaa atacaggtac catatttaaa tagctatttt
    31741 attttaatta ctctatattt agagtataaa ttaaattcca taagtatatt acagtactaa
    31801 cttatttcag atttattctc cttgtacccc tcagttttag taattcttct ataaagcata
    31861 catagtaaaa ttaaaattcc catgtaacct gtatatggat atagtgtacc tactaactta
    31921 tcaaatggca gtaaacctcc tatacaagct aatatactta ccactattgt tataatttta
    31981 aatttagggt ggtcatcttc tacaaatcgg ttagttactg accataacaa tggtacagct
    32041 gtagtgtata ttcctagtaa aagtactact gagaataaaa tacctattat tggagatatc
    32101 ttatcagcta agtaaagtgc tggtatctct tttgtgtata tatttcctat gtttgaaagt
    32161 aatgccaaat tcatcattat agctgctgcc ataagtgcta ctccacctac tataccaccc
    32221 catacagcat ctttcttatt tactgcagaa gctcccattc ctgtcaagaa tgttattact
    32281 attattacat tgtaacaagt ataaagtact cccgagaaat atccatttga tgtagcagtt
    32341 ttaatattta aactatcaac catatttcca gcatttgata aagcatcaat attgctaaat
    32401 aaactaattg ctcctactaa aagtgtaaat attattatta taggtcctat attacctagt
    32461 attttagaaa gccttgtcaa acctaatgaa acagttatta gggaaacgat tgccatacca
    32521 atcctaccta catatggatt taatccatag tactctgata gtgtagctcc tgctcctgca
    32581 atcattatta ctaatgttcc aaataaaaac aatggaccaa accattcaaa aaatgttcca
    32641 agatattttc cacaatatac ttgataaatt tttattggct ccttaagttt caattctctt
    32701 cccttatcta taacttctgc tccaaaccat gaaaatagta ccatagagat tattccacct
    32761 ataatacccg catatccata aaacgtaaaa aattgcagta tttcttgacc agttgcaaat
    32821 ccagaaccta ttacagtagc aacataagct ccagcaaaac ttataaccgt tttaatattt
    32881 actttgcctg acatacacta ctccccccca attaaaatta tttttaaagt gtaagtttat
    32941 taagattata ttagactcat tattgtgata tttcaatata tttttaatta tttaacatta
    33001 gttaacacat tcttaaccat cctttaacat atatcccata atatgtataa atttagtaga
    33061 gtattatata aaatgtattg accagattaa atactgttta ttcattatat gatgataaat
    33121 taacatttat taaaaatatt taactcataa taaaaaaact gttagaaagt aatcgtaaaa
    33181 ttacattcta acagcttttt agttaaaaat tattcaccta aagcatcttt tcttaactgc
    33241 tcaaccttgt cagttctttc ccaaggtaaa tctatatcag ttctaccaaa gtgaccataa
    33301 gcagcaacct ttttataaag aggctttctt aaatctaagt ctcttattat cgctcccggt
    33361 cttaaatcaa agtgtttatt tactaattca acaagttttt cttctgaaac cttgcctgtc
    33421 ccaaaagtat ctataaatat agataatggt ctagctatac ctatagcata tgcaagttct
    33481 atctcacatt tgtctgcaag accagccgca acaatatttt ttgcaacata tctagctgca
    33541 taagcagcag atctatcaac ttttgtaggg tcttttcctg agaaagctcc tccaccatgt
    33601 ctagaatatc caccataagt atctattatt atttttcttc ctgtaagacc tgtatctcct
    33661 tgtggtcctc ctataacgaa tcttcctgtt ggatttatat aaattttagt ctcttcatca
    33721 agtaattctg ctggtataac ttccttaata acatgattaa ttaaatcttc tcttatttta
    33781 tcatttgata ctgtttcaca atgttgagct gatataagaa ctgtatgtac tcttacagct
    33841 ttacttcctt catattcaac agtaacttga gtttttccat ctggtcttaa ataatcaact
    33901 aaacctgttt ttctaacttc tgtaagcctt cttgataatt tatgtgccaa agatatcgga
    33961 agtggcatta attctggagt ctcattacat gcaaatccaa acattatacc ttggtctcca
    34021 gctccaactt tttctatttc ttcttctatc tcttctccag tcttactttc tagaccttca
    34081 tcaactccca tagctatatc tccagattgt tcatcaatag aagttataac tgcgcaagta
    34141 tcacaatcaa atccatattt tgctcttgta tatccaattt ctcttactgt ttctcttact
    34201 aatttaggaa tgtctacata agcagatgta cttatttctc ctgctactaa aactaaacca
    34261 gtagtaactg tagtttcaca agctactcta gattgtgggt ctttttctaa taatgcatct
    34321 aatattgaat ctgatatttg gtcacatatc ttatcaggat gtccttctgt aactgattct
    34381 gacgtaaata aatgtcttgc catttttatt cccccttatt tattcttaat ttttattata
    34441 ggttttacct tatttttaat tttagaaatt tactcaaaat aaaaaaacct ctcctttata
    34501 agaagaggtt aataatcgta attacatact aattaactga cctcatcttt caagactttt
    34561 gtcttgtagg aattagcacc ttttcccatt tgggtggttg ctgggcttca cagggcctat
    34621 ccctcagcct ctcttgataa ggtaatcaag atttaagttt tgttttactt tactagctta
    34681 ctattttttt aaaattttgt caatattttt agtcatattt tttctattcc tttttttgta
    34741 agacaaataa aattttctat ctatctgaaa tttaaagtta ggtcttttta atgcttttta
    34801 ttcatatatt tttttgaagg gggtgttcct attgtattta gctaaagtaa actacagcga
    34861 tgatgatgtt atacagatgc taagttcagt tctaaaaact ataattaatg aaaatacgat
    34921 tgttgtttgc ataggaacag acagggctat aggtgatact ttaggccctt tagttggaac
    34981 aatacttaag aacagtaact ttaaataccc cgtttacggt acactagata accctattca
    35041 cgccttaaat atatatgagt ctttagatac tataaaaaat acacatatac aaggtaactt
    35101 cttggctata gatgcttgct tggggtcgca gagtaacata ggtaatatac agattagaga
    35161 aggacctatc ctgcccggaa aaggtgttgg taaaaaacta cctcaaatag gaaattattc
    35221 tatagtagga attgtagata aaattgatga aaataataaa ctttcattta ataatatacg
    35281 ccttagcttt atattagatt tagctgaaac aatagccttg gctttattag tatccaccta
    35341 atctaaatat aaactaaatg ataaaattct ttatataaaa aggtagatat tttagagtat
    35401 ctgattaaat actccaaatt atctaccttt ttacttttat atttcaagtt tttatttttc
    35461 tactaaagca aacattaatt cacctttaca gacaagttct tcacctacat atgccttagc
    35521 atctgcctta gctatatttt ttctaagagt tgtcatttca atttccatag ttaatgtatc
    35581 tcctggtctt acttctctct tgattctaac tttatctata cctgcaaata cacctagttt
    35641 tcctttgttt tcctctacag acatcattgc cactccacat acttgtgcta gagcttctac
    35701 tattagtact cctggcatca aaggatattc tggaaagtga ccttggaaaa atggttcatt
    35761 aactgttaca ttctttatac caacagctct tttcccaact tctagctctg taatcttgtc
    35821 tactaataaa aatggatatc tatgtggtat taattttttt atttcatcta tatttaacat
    35881 tctaaactct cctaattatt ttcttttgaa agacccacca gtttcaagta agtctattga
    35941 acctaaagct attcctgtac cttttgcaac acaagataat ggttcatctg ctattgtaac
    36001 agttattcct gtcctctgtt ctattatttt atctaatcca tataataatg aacctcctcc
    36061 agtcattatt ataccgacat ctcctatatc tgctgctaac tcaggaggcg ttttttccaa
    36121 aacagcatga gtagcaacta ctatttgctc aacacattct ctaagtgctt ccaacatttc
    36181 tgttgaattt atagttatag aactaggaag tcctgtaatt aaatttcttc ctgttatctt
    36241 catatatttt tcttcttctc tcttaaatgc agaacctatt tcaaacttga ttttctctgc
    36301 tgttctttct cctataagaa gattgtgttg ttttttcata tatttaacta tagcatcatc
    36361 aaatctatct ccaccaacct ttatagattc acttacaaca gctcctccta gagatattac
    36421 agctatatct acagtacctc caccaatatc tataatcata ttaccattag gctgtgatat
    36481 gtctacacca gctcctatgg cagctgctat tggttcttct atgatatata cttctctagc
    36541 tccagcttgt ctcgtagcat cttctactgc tcttttttcc acttctgtga cacctgttgg
    36601 tacacatacc ataattcttg gcataaaaaa tcttccaaat ccctttttat caactatctt
    36661 atctataaaa gattttaaca tcttctcagt tacatcataa tctgaaatta caccatctct
    36721 taaaggtctt atagcgacta tattacctgg tgttctccct atcatctttt tagcttcttc
    36781 tcccacagct aaaacagaat ctgttctttt gtctatcgcc acaacagatg gttcttctaa
    36841 aacgattccc ttaccactaa cataaacaag cacatttgca gtacctaaat ctatgcctat
    36901 atcagctcca gccatttttt caactccttt atttataata ttagattata ttataagcct
    36961 attttaatac tcctataata aagcatatac aaaaatctcg ctttaatcaa gagaaaataa
    37021 atcttttgag agtattatta ttttgctatt tataattact taatatattt ctttttataa
    37081 tttaattcaa taaaaaaagt aggtttttaa cctacatttt tttatgttcc ttctcatatt
    37141 ttaatttcgt tgctaatccc cctctaatat gtctctctga tttatttttg tccagcacat
    37201 ttttaacttc tttggcaagg gatggattta tttccttcaa tctttctgta acatccttat
    37261 gaattgtact tttacttact ccaaatgtct tggcggtttg tcttactgta gtgttttttt
    37321 caagtatata ttttgctacc actatggccc tttcctctat atgagatctc aaagattacc
    37381 cccctcacat aatagcttta atgatatata tgtaaaaaca ccaaaaaata taacaagctt
    37441 aaccaaatat gattaaactt gttatacttt tacttaatta gactcattgg gtctatagat
    37501 ttttctccac tatacgcctc taaatgaaca tgtatacctt cttcactttc tatttgagaa
    37561 gtactaccta cagtacctag agattgtcct tctgttacct tctgttcttt cttaacacta
    37621 acatttttat ctagatttga atatactact acaatgttat tgtcactttt tattttgact
    37681 gattgcccat attcttcatc attaaataca tctactacta ttccgtttaa tagagatttt
    37741 acttctttgc ctttagtaca actaatatct acacctttat gagtttccca aacatcaaga
    37801 gttttagaat aactaggttc tttttctgaa tatcctctta ttactttatc tccaatgtaa
    37861 tttaattttg ttgtactcga tttattttcc tcttttgact tagctttttc taagttttgt
    37921 tttgaatccg ttgcagtagg gatagcatct ttcttgtctt tttcaattaa atgtatttcc
    37981 tcttcactat ctttattagc attttccata attcctttat tagaagccaa tttatctaca
    38041 ttattatttg taaaccaaac tccacctact gctaataaac aaacacatac aaacaaagat
    38101 aaataaaaac catctttttc taacagcttt ttcttcattt tgcacctcca aatatatttc
    38161 tacatttgga ttattgacgt gtttttggca ttttatacaa ttattagtat atatctttta
    38221 tttttgtatc tgtgtagtaa tgtgataata tatcataata tttatagccc tcttctgcca
    38281 ttccttctgc tccccactgg ctcataccaa caccatgacc atatcctttt accacgaaat
    38341 ctatgtatcc ttctccaaat tttatgtcaa agtttgcaga gttcaattta aaaacagttc
    38401 taatgtcttt tccagtcaat tctttatttc ctaattttat tttttctaca gttccggcat
    38461 cacttctttt agttattgaa acttgtttac ttaaattatt cacatctatc acaatagtgc
    38521 tatatgccct tctaagactt ttaacaaaat ctgtgttact tattttaagt gttgacgcaa
    38581 atttagggga atacttatca taaggacttt ccacagactt taaataagga tattttgcag
    38641 aaaatacttc ttcactattt tctgtttttc ctgaagatgt agaaaaataa agaggaagta
    38701 tcgccttatc attataagtt attatttgac ctttagttcc tctaactgct tcttggattt
    38761 tggaatattt attcttaatc cattcttcac catttaattt tttaagagta tcataactct
    38821 tatattcttg acaatgttta taatcagtac atactactgc atttttatgt ttactagatt
    38881 taccatgttc ctgtttatat actacatatg ttctagctgc tacagattga gcttttaaag
    38941 cttctatatc aaactctgaa gacatctcac cagctagtac tccacataaa tagttctcca
    39001 tgtccatctt ttcggttttc cctgttatat gattatatac attgataatt ggtgcttttt
    39061 tatttacagt ttcatagctc actgtacttt tttcttcttt attacctttg tcttcaatat
    39121 cacttttttt aatagttttg tttatagata ctgggctctc tggtttttca gttaattcta
    39181 catttttata agaaactaaa gttataagtg atggaactaa cacagagcaa gtcacaaatc
    39241 ctaacaaaac aaccaatggg ttcttcatat actctcctcc ttagctttta aaaccttgta
    39301 tttaagtata tgaacaaccc tattaattta taactttctt ctataaacca attattaatc
    39361 ttctactatt tcgatttgac cacctagtgc tgttatcttc ttatctatat caacataacc
    39421 tctttggata tggtatattt ctcctatttg agtttctcct tctgctataa gaccgcataa
    39481 aataagggct gcccccgctc ttaaatcagt agcgtttact gctgcaccgt gtagctcatc
    39541 tacaccatta acaaccgcac ttcttccatc tatttttata ttagcaccca ttctattaaa
    39601 ttcagcaaca tgcataaatc tattttcaaa aacagtttct ataactacac cagttccatt
    39661 ggctacagta agcatagcca taaattgtgc ttgaacatct gtaggaaatc ctggatgtgg
    39721 taaagttttt atatctattg gttttaatac ttttggacct acaactctta cagaattgtc
    39781 catttctgtt atttcgcaac cagcttctct taatttagct acaactggtt ttaaatgctc
    39841 cattaaaaca ttttcaacag ttatatcacc ttttgtcata gctgctgcaa ccatataagt
    39901 tgctgcttct attctgtctg gaattacatt atgttctgct ccttttaact ctttaacacc
    39961 ttttattttt atagtattag tacctgcacc tttaacatct gctcccattt cgttcaagaa
    40021 gtttgctaaa tctactattt ctggctcttc tgctgcattc tctattattg tagtcccttc
    40081 tgctaaagaa gctgccatca ttatgttttc agttgctcca acagatggga aatctaaata
    40141 taatttattt cctactaact tttctgttgc tgcttcaaca aaaccatggt ccatttctat
    40201 ctttgcacct aaggctttaa atccttttaa atgtaaatct ataggtcttg ttcctatagc
    40261 acatcctcct ggcatagaaa ttttcgtact attaaatcta gcaagcaatg gtcccataac
    40321 caaaaaagaa gctctcatct ttcttacaag ctcatatgga gcttcacaag tttttatatt
    40381 gcttgcatca acagtaagtg tattttcttt atattcaact tctgctccta catgtcttaa
    40441 taaatctgat ataacatgaa catctcttaa atttggtact ccatttaatg ttgattttcc
    40501 gtttgctaat aaagtcgctg ctattattgg taaaactgca ttttttgcac catctatttt
    40561 aacactacct ttaagtggat tactcttttt tactattatc ttagccatat tttttgatct
    40621 cctcataatt aataatctaa ttttataatt ggtgtggcaa tatatatgag tgtttttccg
    40681 tcatcctcat tatatttaat tcctatattt aaattaattt tttcccctaa atattctaat
    40741 tcataatcat ttaatacttt actatatgct gttatagata aaaagtttac gtctttaact
    40801 tcatctattt gcttagcact catattatat aatatttttt gtaaaatatc atcatatttg
    40861 ttgttttgta acctttttgt gtattctcca acaatacaag cagacacatc tacttgagat
    40921 gaatatttat ttaacacatt ttctacgtta ctataaataa cctctttatg tttatatact
    40981 ttgttatcca atatgtcaac tactatgtaa ctttctttgt tatttttatt tattcctttt
    41041 atagaaattt ctttatcgct accttttata gtagcacata attgtatttt atcgccagac
    41101 cctttttgat tccaatttat tcctttttta tccaacttta gattgttaat tatttctata
    41161 aaaatattat gaaattcttt atttgataaa ttatgattta taacagaatt aattttaaca
    41221 ttataaaatt taaaatttgc ttctgatatt tcaagagctt tacttaatct attgtatcta
    41281 gtatttatac ttgtatctgc ataagatatt gtcattccta taatcattaa tataaaaaag
    41341 cttatagcta attttacttt tttcatagta aaaaatcccc cttaaatatg tttttctgta
    41401 taatagaatt attaacaaat ttaagagaga tatactttct caatatgtat ttttatacat
    41461 ttttgtattt ttcatctaat aatctctttc aaactcttca atctcaattt tctctatcct
    41521 tctcctggac ttgccaattc cttatatgta tcaaatacat cttgcattaa ttcttatata
    41581 ttatcttctg taatataaat tacttagtct atactt
//
LOCUS       DAEQJM010000030        38689 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.030, whole genome shotgun sequence.
ACCESSION   DAEQJM010000030 DAEQJM010000000
VERSION     DAEQJM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38689
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.030"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            300..1136
                     /locus_tag="KRQ43_001972"
     CDS             300..1136
                     /locus_tag="KRQ43_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH2742328.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFKFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1489..3066
                     /locus_tag="KRQ43_001973"
     CDS             1489..3066
                     /locus_tag="KRQ43_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH2742329.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            3059..4243
                     /locus_tag="KRQ43_001974"
     CDS             3059..4243
                     /locus_tag="KRQ43_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH2742330.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVITNNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     TL"
     gene            4261..4860
                     /locus_tag="KRQ43_001975"
     CDS             4261..4860
                     /locus_tag="KRQ43_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH2742331.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4884..5354
                     /locus_tag="KRQ43_001976"
     CDS             4884..5354
                     /locus_tag="KRQ43_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH2742332.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEALVSMGEQVK
                     EGTPMLKINRPLIELKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5711..6457
                     /locus_tag="KRQ43_001977"
     CDS             5711..6457
                     /locus_tag="KRQ43_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBH2742333.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6519..7193
                     /locus_tag="KRQ43_001978"
     CDS             6519..7193
                     /locus_tag="KRQ43_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2742334.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCLNCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCALRCMMSCPWSL
                     RYANQK"
     gene            7561..8907
                     /locus_tag="KRQ43_001979"
     CDS             7561..8907
                     /locus_tag="KRQ43_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH2742335.1"
                     /translation="MEIETKTPDWINVLELNSKIDITWKYDVSNMIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIVGTTNFITRGVSNI
                     SIITLEGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLFHFEHLFISGFSGI
                     GIEIPYYSTGNDIIVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     REIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITKCGQYYKSVDYNTYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNKVMLTC
                     YAEADELIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSIEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8934..10334
                     /locus_tag="KRQ43_001980"
     CDS             8934..10334
                     /locus_tag="KRQ43_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH2742336.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSSKLQEIIDAAPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GEPGHYENLFFSGFSGIALDMPNNSTANDITVFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDKVIKMHKPEVGDIMSTIIKDENILSAHYGGTWGKIGE
                     KIEFGITVHYYKLIEK"
     gene            10544..11980
                     /locus_tag="KRQ43_001981"
     CDS             10544..11980
                     /locus_tag="KRQ43_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH2742337.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPDLQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSPTETTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNEEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKDYEGYGSYKINNITIDQCGYCGFLFDSVKGSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSSPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGKETVYYYKHHEPDKTNQIK"
     gene            12324..13268
                     /locus_tag="KRQ43_001982"
     CDS             12324..13268
                     /locus_tag="KRQ43_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HBH2742338.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13437..14369
                     /locus_tag="KRQ43_001983"
     CDS             13437..14369
                     /locus_tag="KRQ43_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBH2742339.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14474..14941
                     /locus_tag="KRQ43_001984"
     CDS             14474..14941
                     /locus_tag="KRQ43_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HBH2742340.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGETMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15185..16039)
                     /locus_tag="KRQ43_001985"
     CDS             complement(15185..16039)
                     /locus_tag="KRQ43_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBH2742341.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16205..18169
                     /locus_tag="KRQ43_001986"
     CDS             16205..18169
                     /locus_tag="KRQ43_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH2742342.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLSEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYIGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVAADQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSCCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFVKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLLEESI"
     gene            18169..18630
                     /locus_tag="KRQ43_001987"
     CDS             18169..18630
                     /locus_tag="KRQ43_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2742343.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSDAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18633..18953
                     /locus_tag="KRQ43_001988"
     CDS             18633..18953
                     /locus_tag="KRQ43_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH2742344.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            18969..20069
                     /locus_tag="KRQ43_001989"
     CDS             18969..20069
                     /locus_tag="KRQ43_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH2742345.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20189..22789
                     /locus_tag="KRQ43_001990"
     CDS             20189..22789
                     /locus_tag="KRQ43_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBH2742346.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKHVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDYILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNVFIEESGYYILKVR
                     INVQLPALGYKVVSFESSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLILKDSGNAGDTYDFSPLKNDEDIKLSFDRVYTEKTLGYEKLVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKKLEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPEKY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
     gene            23258..23593
                     /locus_tag="KRQ43_001991"
     CDS             23258..23593
                     /locus_tag="KRQ43_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2742347.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            23730..25007
                     /locus_tag="KRQ43_001992"
     CDS             23730..25007
                     /locus_tag="KRQ43_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HBH2742348.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNNSQKDSNNDNNDNG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            25128..26516
                     /locus_tag="KRQ43_001993"
     CDS             25128..26516
                     /locus_tag="KRQ43_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH2742349.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSESAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            26887..27600
                     /locus_tag="KRQ43_001994"
     CDS             26887..27600
                     /locus_tag="KRQ43_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HBH2742350.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLFLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            27718..28587
                     /locus_tag="KRQ43_001995"
     CDS             27718..28587
                     /locus_tag="KRQ43_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH2742351.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSITSNIITV
                     IPEKSRVEVLQVDGDWSKIVYDDKIGYVFNYFLSTDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(28742..29887)
                     /locus_tag="KRQ43_001996"
     CDS             complement(28742..29887)
                     /locus_tag="KRQ43_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH2742352.1"
                     /translation="MSTYYVPPINLLGKGCLNEAKDSIKSLGTKKAFVVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYDEVKQNPTVTNVDKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIVAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAVEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKEKIIELFMKIS"
     gene            complement(30220..30996)
                     /locus_tag="KRQ43_001997"
     CDS             complement(30220..30996)
                     /locus_tag="KRQ43_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH2742353.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            31578..32552
                     /locus_tag="KRQ43_001998"
     CDS             31578..32552
                     /locus_tag="KRQ43_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH2742354.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            32650..32955
                     /locus_tag="KRQ43_001999"
     CDS             32650..32955
                     /locus_tag="KRQ43_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH2742355.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGNEISFKLKDKTVKTITALDNI
                     TIYHKLAIKDMAQGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            33111..34271
                     /locus_tag="KRQ43_002000"
     CDS             33111..34271
                     /locus_tag="KRQ43_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH2742356.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            34321..35223
                     /locus_tag="KRQ43_002001"
     CDS             34321..35223
                     /locus_tag="KRQ43_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH2742357.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESIFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            35303..36196
                     /locus_tag="KRQ43_002002"
     CDS             35303..36196
                     /locus_tag="KRQ43_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBH2742358.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNKLNIC"
     regulatory      36249..36430
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            36658..37788
                     /locus_tag="KRQ43_002003"
     CDS             36658..37788
                     /locus_tag="KRQ43_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2742359.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            37860..>38689
                     /locus_tag="KRQ43_002004"
     CDS             37860..>38689
                     /locus_tag="KRQ43_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH2742360.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     "
BASE COUNT        15101 a         4090 c         6808 g        12690 t
ORIGIN      
        1 atataattaa gttaaaatac ttgagaatac tggaaaaaac tgaaaataat ttttgtaata
       61 taaaatgtcg attgatttta aataattaaa tatacataag aaataattaa atatatttca
      121 atgaaaatat gataaaatat gacaaattaa ttgatgacaa taaaaaatat tttgttattg
      181 tagtattata gggtaaattg caaaatatat acgaaagtaa aattttaaat attgacatta
      241 aattaaatat actatactat gtaagtgtga tgagagaatt tttttagagg ggatttatag
      301 tgaatataaa aaagatattt aataacaatg tagtagtaag ctccctagaa gatggcacag
      361 aaataattgt cactggtgct ggagtaggat ttaagaaaaa agtaggcgat ttgatagatg
      421 aaaatttgat ttctaagaaa tattttgttc aagacgatca aagggacaaa tacaatcaaa
      481 tacttaataa gacctctatt gaatacttta aaatttcaga agaaattata gaaaaggcta
      541 atgaagtttt aaatactcaa gtgaatgatt caataatatt agccttaact agtcacatag
      601 aatttgctgt ccaaagagaa aaacaaggta taaaattacc aaacttaata ttgaatgaga
      661 caaaacaact ttatagggaa gaatttaaat ttggattatg ggcaattgat gaaattgaaa
      721 aaaggatagg aataaaattg cctgaagatg aagcaggata tattgctatt cacataatca
      781 atggtttgga aaattctcaa aaagatgaag gtattaatat actagagttt tcaaaacaag
      841 ttattcagat aattgaagaa gtacatggat ttaaattgga tgtaaattca ttaaattata
      901 ctagacttat aactcactta aagttttttg ttcaaaggat tctccgaaaa gaaacttaca
      961 atgatagtga tattgaagat atgtataagt tagtgaataa aaattacaat aaacctaaag
     1021 tgtgtactga agaaattgca gcattggtat tagacagatt tgaatataag attagtaaag
     1081 aagaagaatt atatttaatg attcacataa ataaaataac aaacagtggt tgttaggatt
     1141 gtaactgata aagcaggcaa aacctaagtc aatgagctta actattagat taagtttttt
     1201 gatttaggtt tttttattag atacaatcaa aatacagaca gtgactttta ggattgtaac
     1261 tggttaagca ggcaaaacct aaatcattga atttaactat taggttaagt tttttgattt
     1321 aggttttttt attagataca atcaaataca gacagtgact tttaggattg taactggttg
     1381 agcaggcaaa acctaaatca ttaaacttaa ttattaaatt aagttttttg atttaggttt
     1441 ttctataaat ttgattatgt ttttagataa aaataggagg ggaaaattat gaaaaaaaat
     1501 aagttaggtt tatggaactt cttccaaatg ttagggaaaa cgtttatgtt cccaatagca
     1561 ctacttagtg tttctgggat gatgctagga cttggggcag gttttacaga ccctaagatg
     1621 attgaaatgg ttccatttct agggaatgaa tatgttaact tagttttaaa cttcatgtta
     1681 acaataggat tatttgcatt taacaacttg ggagcattat ttgcaatggc aattccacta
     1741 ggattattaa aaaaagaaaa agagtttggt gctttttcag gattagtagg atttatagca
     1801 atgcatatag gtacaaattt ttatttaaca agagctgatt tgttagtacc agcagaacag
     1861 atgtcaacta atggtcaagc tatgattatg ggtatacaaa catataatac aagtgtttta
     1921 ggtggtattg tagcaggatt aattgtttat gcaatatatg ataaagttag taatttaaag
     1981 ataccagaat cattaggatt ctacagtgga ccaagattag ttccaattgt tagtttaata
     2041 gttatgagta tagttggatt attaatacct attgtttggc caccattttt caatgcattc
     2101 caaagtttag gaagatggat ttcttcagca ggaccattag gatatttttc atatgcagtg
     2161 gcagaaagag ttacaattcc atttggacta aatcatcttg taacatctgt attccgtttt
     2221 acaccaatag gtggaactgc tgttattgat ggagaaacgt actttggtac attgaacatg
     2281 tttatggcat atgtagaaaa taatcagatt atacctcttg atttagctgg taaaatggaa
     2341 caaggtaaat tgatgattca atatggatta gctggtgctg cattggctat ctaccgtaca
     2401 gcaaaaccag aaaatagaaa ggcacttaaa ggacttttaa tatcaggagt gttgacagtt
     2461 attataggtg gtataagtga accaatagag tttctattct tattcatatc accagcatta
     2521 tttgctttcc atacatttat gaatggtcta gcaaacatgg tacttccata cttaggcgtg
     2581 ttgatgggat tcacaggaga tttaattgca tttataagtt ttggtgtgtt aagaggaaca
     2641 gctacaggat ggccaatagc agtattagta gcagttttat attttgcaat atactatttt
     2701 gtatttaagt gggcaattat taagtttaat ataaagaccc caggacgtga ggataaagaa
     2761 ataaaagtat ctgaaggaaa tggttcagat ttcaaaaatt tgtctacata taaaggacaa
     2821 caaatgatat ctgctttagg tggtcaatct aatatattat cactagataa ttgtgtaact
     2881 agattgcgtt taaaactaca agatgtatca ttaataaatg aggatgcaat taaagaggct
     2941 ggtggtatag cagttgttaa attggatgag catacaatac aagtaattat aggaactcaa
     3001 gtgtattctt taagaaagca gatggataaa gctatggaag gtcatttgga ggcatgtaat
     3061 gattaatttt gataaaaaag tagaccgatt gggtacatat tgtacccagt gggactatgt
     3121 agaagataga tttggtaaga aggatttgct tccttttaca atttcagata tggatttaga
     3181 gtttccattt gaaataacag aggtgttgca ggaaaggtta aatcatagag ttttgggata
     3241 cagtagatgg aaacatgatg attttagaaa ttcagttacg aattggtata ttaaaagatt
     3301 taattgtagc gttgatagta actggatata ttatagtcca agtgtaatgt attcaattag
     3361 caaacttatt gagatgttaa gtaatgaagg agatggaatc cttataaata ctcctgcata
     3421 caatgctttt tatgatgtga taacaaataa caatcgtaat attataaagt cacatcttgt
     3481 aaataggaat ggattctatt caattgattt taatgatttt gagaaaaagt gtaaaaaatc
     3541 taagatattt attttatgta atcctcacaa tccaactggt agagtatgga gtgagttaga
     3601 acttgttaag atgataggaa tttgtaagaa taatgatgtc aagataatat cagatgatat
     3661 acacatggat attgtatatg acaatagaat gacacctatc ttaaatgttg caaaggacta
     3721 tttagattct gtattcattt gtacatcagc gtctaaatct ttcaatatac cagcattgac
     3781 tgggtcatat gtgattatac caaatgaagg tattagaaat aaatttgaaa atatcactag
     3841 ataccgtgat tttgtaaatt cgccagcaat tctagcaata ttagctacaa tggtctgtta
     3901 tgatgactgc gaatattggt tagatgaact attaaaatac cttaaagaga atcttaaata
     3961 tacgattgat tatataaaag ataatttaga accattgaaa ttggtcatgc cagaaggctg
     4021 ttactttgct tggatagatt tttccgaact taaaataagt ggtgagaaat tccaaaaatt
     4081 attgatggat attggagaag ttgctattat gtcggggtct gtatatggtg aagaaggtga
     4141 gttttattta aggttaaatg tggcatgttc aagagaaaaa cttgaagatg gtttaaatag
     4201 gattaaaaaa actatggatt atattgcaaa aagaacttta tagtaggaag ggagatagtt
     4261 atgggatatt taaaaacaat ggttgatgtt atgactactg aaatgaatgc cataagatgt
     4321 ttaatagatg aagcaggaat agaatatgaa agtatagtta gtgaaattgc aaattgtgaa
     4381 ggcaaagtaa tttttatggg tgtaggaaaa tctgcacata taggtaagaa attggcagct
     4441 acatttgcta gtactggtac acctagcttt tttgtacatg caacagaggc agtgcatgga
     4501 gatttaggaa tgattgaaag taaggatatt acaattttaa tatcaaatag tggaaattct
     4561 atggaagtgg taaactgtat aaaatatatt aaagcaatag gttctaagac aattgcattt
     4621 acttcaaaca gaaattcagt actggcaaaa gagtgtgatt atgctttaat atatcctgca
     4681 aaggatgaag cagaccattt aaatctagca ccaacaacat catctacaat tactttggtt
     4741 ttaggagatt ctattgcatg tgcattatct aagagtagta attttggttc ttcagatttt
     4801 tataagtacc atccaggagg aagtttaggt gagaagttaa aaacagctaa caatggataa
     4861 aagcaaaaag gagagtagtt tttatgttca aaatgtttaa aaaaaaatca ataaaatcac
     4921 ccatatcagg aaaagtaata gagttatcta aaatacaaga tggtgtattt tctcaaaaaa
     4981 ttatgggaga gggtgtagct atagattcta caggagacat tgtatatgct ccaatcaatg
     5041 gaaagatagt agtagtagca gagactaaac atgcatttgt aatagaatta gaaaatggga
     5101 tggaacttct tattcatgtt ggtttagata ctgtaaattt aaaaggcgaa ggttttgagg
     5161 cattggtgag tatgggagaa caagtgaagg aaggaacacc aatgttgaaa attaaccgtc
     5221 ctttgattga attaaagggt atatcactta ttactccagt tacaataact aatcattcag
     5281 agtacaatat gaatacatgt aatgtaggca atagcgttga aggtgggaaa gatactgtaa
     5341 ttgagtttaa ataaagaatt aaaatacaag gttaatattt ataaatacct ataaacttat
     5401 gttttataag attgattgta tggatttatt gtataaaaaa gaactcttta attataaatt
     5461 aaggagtttt tttattttgt aaatattgtt tagatttata tagaaaaaca cttagtaata
     5521 aatagaataa ataagtattt atatagctaa aaatctaaat agttttgttt aaatatattt
     5581 ttatattttg taatttcaaa ttaataaata attagaattg ataaacaaaa aataaaaatg
     5641 ttgattatat taataaactt taatataata tatttatgaa aaatgtaaat tgtgaaatgg
     5701 aggtagtaac atgaaaattg aaaatctttc tattgatgat attaaacgag gctatatatt
     5761 taatgatgat ttaaattgtt atagttgcat taaatgtaca aaaacatatg aggtaggaga
     5821 aatatataaa ataggtaata gattctttga agcttcaaaa gctattgaac ttcatatgga
     5881 attagaacat agtgattatt tagagcaatt gcttaatagt gattcaaagt acaacacatt
     5941 gactgaaaat caaaaacaat tatttcaatt atttattagt gatttaccag ataaggagat
     6001 agcaaaacag gttggagtat ccacatctac tatacgccat caaaaattta ttttcagaga
     6061 aaaagcaaaa caggctaagc tctatttagc actatatgaa tctgtatttg aagataaatc
     6121 taataaaagt agtactataa taccaatcca tgaacatgct cgaatggtag atgaaagata
     6181 tgtagtaact gaagaagaga gaaaacacat tttggataca tcatttgaaa gtatgaatcc
     6241 tttaaaatta aaagtatttt cttcaaaaga aaagaaaaag gtcgtaattt tatctaagat
     6301 tttggaacaa tttgaacgtg ggaagaaata ttcagaaaag gaagttaatc agattttaga
     6361 atctatatat gatgattttg caacaattag aagatattta attgagtatg gctttatgag
     6421 tagaaataaa gaatgtacaa agtattggtt aacataatta aaataataaa ttttactaat
     6481 gtgtaatgtt atttttatct aggggggagg agttaaatat gaatgatgaa ttaaaatcta
     6541 ttttatacaa taaaggtgta gacattgttc gctttgttga tatatctgaa tttccaataa
     6601 atcaaacaca aggtttttct aaagcaattt tattttgtat agggttatca aaaaaattta
     6661 ttacagatat atacaataac ttacctacag atagtgatga gtttttggaa aaagaggaga
     6721 aagtagaaga attagctgac tggatttcaa aatatattca aaataaagga tatagagcgt
     6781 attctcaatc ggagaaaaac aatctagaac atggatattt tgaaaaagcc tatattaatc
     6841 cagaaatgca atcagggatt agtcctttac cacataagac aatagcaaat attagtggca
     6901 ttggatttat gggaaaaaat aatttgtttg taacagagga atacggatgt gcttttagca
     6961 tgtgtacagt acttacagat gctccaattt ctgttgaaag atatcctttg attgattcaa
     7021 aatgtttaaa ttgtaatgtt tgtgtagaga actgtcctgc aaaagctata catggaaatg
     7081 aatggacttt acctggaaaa agagaatcta ttattgatgt ttcaaagtgt ttttgtgcat
     7141 tgaggtgtat gatgagttgc ccatggtcat taagatatgc aaatcaaaaa taactttact
     7201 agagaaggta ttaaattgaa tattataaaa tttttaaaat gtaagattat ataagatttc
     7261 tcaaaataaa aatttgtata gaacactcag aaatgagtgt ttttctattg ggattaaatt
     7321 atattgatac aaagcttaac tattttaatc attatataaa atttgtatta aaaaattaag
     7381 aataacttgc taatagtaaa aatataatga gattataatt gatttataat ataactgtaa
     7441 tgatgttgta aaatgaaaat tgtcatctca aaattcccaa aaagagtaaa agtcacttcg
     7501 gttatagtca aaaaattttt tctgtgaaaa gaatttagat ttaaaaggga ggaattaatc
     7561 atggaaattg aaactaaaac tccagattgg attaatgtac tagaattaaa cagtaaaata
     7621 gatattactt ggaaatatga tgtaagtaat atgatacaag atattgtctc tgataagtca
     7681 ctagaaggtt ccattatata ttttccaaaa ggtaattact tatttgagaa aggtattaaa
     7741 attagtcaac aaataacact tcaaggagat tcttattatg gaggagataa tcaagtatca
     7801 aatttagata aaaaacaatc aatcgtagga acaaccaatt ttataacccg aggagtttct
     7861 aatataagta ttattacatt ggaaggaaca agtcaatgta tcaaaaatat taatttttat
     7921 tatgatagtc atgatataga gaaaatacca cctaaaaatg tatctgctat tacagaatat
     7981 ggagaaacac aaggactatt tcactttgaa cacctgttta tttctggatt ttcaggaata
     8041 gggattgaaa ttccatacta ttcaactggc aatgatatca ttgttagttc atgtggtctt
     8101 ggtatgaggc ttggagagaa gtcaatgctt tctagtagca agatttatga atgtaaaaat
     8161 ggaatggaga ttactactgg tgttagctta aataatgtga gaatagaaga aataagagaa
     8221 ataggtatta ataataaagg atttggtttt aacctgatta tgaatcttat ggtcgaccaa
     8281 tgtggatatt gtggatttat gtttgaaaaa atgtgttata gccagataac tgccagaatt
     8341 actaaatgcg gtcagtatta taaaagtgtt gattataata cttatgagaa tatggaagat
     8401 agaaaagaag aagcttattc cattttttat ggagatattt tagaaaattg caatattgta
     8461 ttgatgaata gtaatattga taccttagaa aatgattcac ttgatgaaca taagatatat
     8521 gtaatcaagg caaatgaaac aaacaaagta atgttaacat gttatgctga agcagatgag
     8581 cttatacagt gcgcaaaggg caacttgttg ctagaaaatg gtgaaaatac ttataaattt
     8641 tataatggtg agatttgttc tgtaggaggt gttcaaattt ctgatataga tgaaaaagat
     8701 ttaatcaaaa taatcgagaa cactctgtat atagatgata aaggtaagta cttaatggtt
     8761 cctagattaa aaaagaatac tgtaatatat tcagtactag attctataga agaaataaat
     8821 aaattacatg gtggaatatg ggaacagatt gatgtaaaag tattagctgg ggaatctatg
     8881 tactattata aaaagataaa agattaaatt atcaaactag gaggtagtga ttaatggaag
     8941 agtctataat aattaaagat ataagtggct ggattaatgt acttgattat gggatttgta
     9001 atgatgaaac aaaagatgta agttccaagt tgcaagagat tatagatgct gcaccagaag
     9061 attctattat atattttcca aaaggaaaat acttatttga aagtggtgtt aagattaaga
     9121 aacgattaac cttatgtgga gattcttata ttttggcgaa tgttcctaaa aacactgctg
     9181 gagtaacaca atttactttt aaaggaaaga aaaatcctaa aagtgaaaat atagcaatta
     9241 taacagcaaa aagtgtaaga cactgtatta agagcatttg cttttattca gatagttgtg
     9301 atagagatat gacatctaat catgaacctc caacagatgg aaaacctaga tttcatcata
     9361 atgtaattat aaattataga aatatatcgg ctattgtatg tgaagataaa cagggagaac
     9421 caggtcatta tgaaaacttg ttttttagtg gtttttctgg aattgcactt gatatgccta
     9481 ataattctac agcaaatgat attacagttt ttacatccgg acttggaatt agtacagggg
     9541 aaaattcaac gattgctaac agtaaggttt ggggctgtgt tgatggaatg ataatttcta
     9601 ctggaacttt tataaatggt atgagggtag aagaaataaa aaaagttgga attaaaaata
     9661 ttggtagagg tttaaatttt attacaaata tcacaattga ccaatgtgga tattgtggag
     9721 tttggtttga ttctatatcc aatgttcaga tatcaggaaa tatcacaagg tgcggacagt
     9781 actattatga tgtaagctat gataattatt taatgttgga taatagagtt aaagaagcat
     9841 attctttatt ctatggtaat ttattggagt caagtaatat agttttgtca aataccaata
     9901 aagataattg ggaagatttc aaagaggata agcataaggt gtatcttgta gaagcacttg
     9961 aaaccaagaa tgtactatta acatgcaata tagatgctac tgactggatt gttaagtcag
    10021 aaaaaggaaa tttaacgtac aataatatgc gacaaactgt tatattttac gatggaaaac
    10081 taagtagtat caatggaatt ggtatatctg atgaagatta tggggataaa gtcaagataa
    10141 aaaaaggaaa tatatatata aatagtaagg ataaggttat taagatgcat aaaccagagg
    10201 taggtgacat tatgtcaaca attattaaag atgaaaatat actttccgct cattatgggg
    10261 gaacatgggg gaaaattggt gaaaaaatag agtttggaat aactgtacac tattataaat
    10321 tgatagagaa ataagtaaat acgtagtatt tgaatagatg tattttattg gagagctagg
    10381 actatagttt taatgtaaat ggtttggtaa tagcatggat tgaataatat aaaaataata
    10441 taaaaaatta atttgattat gtaaaattct atgaagtagt aaacctgtga ctttagtcat
    10501 ggtaggttca aattaagtaa atgggaaagg aatatataat attatggaag gaagaactgg
    10561 gattaaagat ggaagatgga ttaatgtagt agaaagaggt attaaaaatg atggttcgta
    10621 caacataggt cctgatttac aggatattat tgatgaaata gaaacagatt tctgtgtctt
    10681 atattttcca aaaggaaaat acttatttac aagtggtgtt aaaattaata aagaaattgt
    10741 attacaaggt gattctaatt cacctacaga gactacacaa tttataactc gtggagtaga
    10801 aaatatgagt attattacat tgacagggaa gaaacaatgt attaaaaata taaatttcta
    10861 ttctgatagt tgtgagatac aggtaaatga agaaccaccg acaaaaggta atcctaaata
    10921 tcattatgag atgattatta ataagaatga aaaaaatgtt gagatgaata atgtatcagc
    10981 aattctgtat gataatagta agaatatgat taaaggtcta ggtcattatg aaaatattta
    11041 tataagtggt ttttcgggta caggaattag gataccatat tactcaattg taaatgatat
    11101 tacagtttca tcttgtgggt tgggtattga tacaggaata gacacaatta tttctaatag
    11161 tagaatatct aagtgtcaaa atggaatgag gattagaact ggaactagca taaataatgt
    11221 aagaattgaa aaaatacaga aagttggtct tataagtagt caagttaagg attatgaggg
    11281 atatggaagt tataaaatta ataatattac gattgaccaa tgtgggtatt gtggtttttt
    11341 atttgactca gtgaaaggta gttatttttc tggtattata agaagatgtg ggcagtatta
    11401 ttataataca gattatgaca catatttaag tattaaagat agagtagaag aagcatattc
    11461 tttattttat ggaaattatt ttacagaatg taatattgat ttagttagtg ataataagga
    11521 taactgggat gatggcttag aatataaaca taaagtttat gtatttaaaa cccttcaaat
    11581 accaaaatta acattgagat gcaatataga tgcctatgat tatatcgtta aatcggtaca
    11641 tggaggaggt aatttaatgt taaaaaataa ctttaacaat tatatattta ttgattcatc
    11701 tagtccagaa gttattaatg gaattaattt taattatcaa aagaatggaa acctgttaag
    11761 gttaaataat ggtaaattaa gttataaaaa tggaaaggaa gaaacagcta tattcagacc
    11821 taattatggt cttattgtag catcaacaga ttcagaatgt gaacaaatag agactagcta
    11881 tggaggaaaa tgggagaagc ttggttctga agtaattgga aaagaaacgg tatattatta
    11941 taaacatcat gaaccagata aaacaaacca aataaaataa aatttgtatt atataatgat
    12001 ataaagtttt aatatatagt gtttaccttt aatgtaatat tggtatattt gtatagtatt
    12061 aaatttgtta aaaagtaaaa ttgtagggtg cttgaaaata gcaccttttt tagtttcatt
    12121 ataaaattag ttttgaaagt ttaggaataa tgtatattta tttttaaaga attataacct
    12181 tattaaggat attttaaatg ctagaaatga atcagtaaat catactggaa ttatcttaaa
    12241 tgttttgatt aaattaagta tttagagcta taattatatt aaaaatatat taggacataa
    12301 ttatattact atggaggtta aatatgatag taagtgtgag tagaagaact gatatacctg
    12361 ctttctatag taagtggttt tttaacagac ttaaagaagg ttttgtttat gtaattaatc
    12421 caatgaatcc aaaacaggtt agtaagatag agttaaatcc acatactgtt gattgttttg
    12481 tattttggac aaaggatgta actccaatgt tatatgattt aaataaatta aaagactata
    12541 aatattattt tcactatact ataacatcat atggaaaaga agtagagaca tgtattttag
    12601 ataaaagaaa ggtaatagat tcatttaagg aattgtctag aaaaataggc aaagaaagag
    12661 taattttaag atacgacccg attttcttaa gtgaaaagta cacagtagat tatcatatca
    12721 aagcatttgc gagtttatgt aatcagcttg atggatttac agaaaaatgt ataataagtt
    12781 ttatcgattt atataagaaa acaaaattta atactaaagc attacatata aagccaatag
    12841 aaattacaga aatagaaaca ttatcaaaag aaatttctaa gattgctcat aagcatggga
    12901 taatacttga aatgtgttct gaagaatata atttaagtaa atttgggatt ggaaaaagta
    12961 agtgtattga tgatagatta atatcaaaaa ttataggatg tgaagtagag gtaaaaaaag
    13021 atagtacaca aagagatatt tgtggatgtg ttaaaagtgt cgatatagga caatacaata
    13081 cttgcagaca ttattgtctg tattgttatg ctaactttaa ttatgcaaaa gtagaagaaa
    13141 actgtaggct ttataaagaa gataataaat tactcataga tactttaaga gatgatgcaa
    13201 aaataagcat tagagatatg aagactatta aagtagataa gaataaacaa attagtatat
    13261 ttgattaaaa taaatatact aattacctta atatatcaag aatatagata cttttgataa
    13321 caaaattaaa cttaatagat attttctata taagaaagat ggtcataata tgtcaatttg
    13381 accatctttt tgatataatt aaaacacaaa taatttagta acaaaggagg cagaacttga
    13441 atttattaaa aaaatatcct atacctattg caagtttgat tttgtcaatt tttactttag
    13501 gtaacttatt acaatcttat agtgaatcat tacgtaatgt aattggattt ataggattta
    13561 ttttgtatgc aatttatata gtcaaaataa tattacttag aaagggtgtt aaagagcaat
    13621 tagagaaccc tttaatatca agtacatttc caactataac aatggcaaca atgatatttg
    13681 ctacatatat aaaaccatta tctttagaat taagtattat gatttggagc ataggaattg
    13741 tgggtcatct tgtgttaata gttttattta gtaagaagtt cttagttaaa ttctcaataa
    13801 aaacggtatt tccatcttgg tatatagtat atgttgggat agttgcagct agtgttacgg
    13861 caccagcatt taatcaactt ttgattggca aaattgcttt ttggatagga tttgtatctt
    13921 atatagttct tataccagta attttaaaga gagtatggat aatcaaggaa atgcctgaac
    13981 catctttacc aagtatagct atattagctg caccagggtc actattattg tctggatata
    14041 ttaattcttt ttcagataaa aataatgtag tattatactt gttattcata ttatcaattg
    14101 tattttatat tatagttttg ggatacttac cgaaattatt aagattgcct ttttatccga
    14161 gttttgctgc atttacattc cctatggcaa taagtgcaat gggtatgaaa ctaatgaatg
    14221 gttatttaac taaatcaggt cattttataa gttggatttc atatgcttct aagttagaag
    14281 agataattgc tacagtgatt attttatatg ttttagtttt atttattata tatcttagta
    14341 aatctgaaac tacatctaaa gctaaataag aattattaaa tatgtgtatt taataggaat
    14401 attgatataa atatatgaag ataagataaa ccatagaaac ttaatttagc ttaattttat
    14461 tggaggaaaa caaatgaaaa caaaagaaga atatttaaaa gaagttagaa acatatcaga
    14521 agaatacttt agaaaaggag agtttttttg ctctgaagca gttcttcaga caataaatga
    14581 tgctttaggc caacctttaa gtccagagat aactaaatta gcatcaggat ttccgatagg
    14641 acttggaaaa gctcaatgcc tttgtggagc gatatctgga ggagagatgg ctttaggtat
    14701 agtatatgga agagtacatg gagaaactat gaatccaaag atgtttgagc atgctaaagg
    14761 tttgcatgat tatattaaaa aagagtatgg tgcaacatgt tgtagagcta ttacaaagaa
    14821 atgggatggt gataacttta tgtctcccga aagaaaagag cactgtatta aaataacagg
    14881 tcaagttaca gagtgggttg cagataagct tatagaagat gaaaaactta atatcaaata
    14941 gtgtaatatt agttggtgaa tttataaagt taaatttact tatagtataa gatacttgat
    15001 attctcgtat tgatagaaaa atttatagca tatgtattta atgaaatata cttatattta
    15061 gagtgtggtt taatttcata aatacatatg ctattatttt aagtatataa gcaaatttat
    15121 ttaaataaat agaaacagtt aatttatatg tacaaaacta tatatgatta gtgtaaataa
    15181 atacctattt tataatactc aacataaaga caccagacat gattagtatt ataccaataa
    15241 aaatagcaag ccattctttt ttgttcttct tttctttaaa aaatataatc cctcctaaag
    15301 tggctactat cacacaactc tgagagatag aaaaacttat tgtaactccc aatgtattag
    15361 tcgttatgaa catacctaaa tttgctattg accacaatat accagtaatt aaattgaata
    15421 aaacattttc cctatataca atctctttag aaaaatactt gacaataata gatgaagtta
    15481 tcaacatacc aacagattga ggtaatataa ttctatatcc ttcaattaaa aatatttgat
    15541 tagttacaac atataatgat aaaaatagag atgataataa tacaactcca acacatttta
    15601 acatattttt atctgtagat tttttagttt gataattagt gagaagtata ccaagtatta
    15661 tacataatat tgataaagaa ccaatcagta acattttaga actggtccat tcattaaaca
    15721 agattacagc taataatgtc gtaaaagtta attgtgaacc atttgaaatt ggcattactt
    15781 tagatacact agcaatttga attgctttaa actgcattaa ttgtcccaaa ctccagaata
    15841 tgccagaaat catacttata caaaatgaaa aaaatgtaat ttcaggatgt ataaccagag
    15901 ttattatagt ggaaaatata aacgcactta tggatgtacc taaaagctgt tcatgaggag
    15961 aacttttctt tagatttgca actatgggca tcaatcccca tcccattaca ggaagtaaag
    16021 caataattat tgtcagcatt aaactatttc ctttcatatt aaatttagac agcttttaat
    16081 ttatcatcta aaattaaagt gttcaataca taaaaattac cgtatttaat caggaaatat
    16141 tagtagtttt ttagaaaaac attttccatt aaaataaaga taaagggaag gagtaaaatt
    16201 gaaaatgtta actgatatga ttcaaaatcg tgaaattaaa ataataaagt ttttattaaa
    16261 agaaggtcat acaactgtaa aagcaatagc agatgattta gatgtttcag aaaaaacagt
    16321 ttcaaaatct cttaaagaag tagaagcagt gcttaaaaag ataggtcttt ctttaataag
    16381 aaaacctaag ataggtgttt atattgatgg agatttaaaa aaaatacttc cttacctaga
    16441 taataaagga agtcaaattc ctacaaccag agaggagaga gttatctata tatattcagt
    16501 acttttaaag agtaatgatt atattactat acaacaactt tctgatgaac tatatataag
    16561 tcgtggaact attgaaaggg atttatcaga agttgaaaaa ctgctaaaaa acgaagggat
    16621 ttccatatat aagaaaccta gtaagggaat aaagttaaat ataagtgaaa gagataaaag
    16681 acaacttact gctaagttta tacataaatt ttggagtaga aactggtata ttaagcaaga
    16741 gcaagaaagc ttttatcaag catttgaaaa gatacaggca gatgtaaatg gtattttttc
    16801 ggaagatgat ttatcaataa ttattgatat tcttaggaat ttcagcagag aaagaaaatt
    16861 tgagttctct gattatgaat ttcagtcatt agttattcat ttggcaatag ctgtagagag
    16921 aattagaaaa ggcgaatata tagaagaaag tttgtatatt ggtaatatag aaaataatca
    16981 aatgtcaaat accaattatt tagcaaaaca attagaagaa aaattttcaa tattattacc
    17041 aaaatctgaa attggatata taaatttaca tttagtagcg gctgaccaac atagagatac
    17101 taatgaacta aaaaatactt caactaatcc ttgtgaaaca agtacaaata atatatcaaa
    17161 tcttcgggaa attataaaaa atacattgta tgagacagct tatgacaagg atttaattga
    17221 tggattgact tcacatgtac attcatcaat aaatagactg aaatatggac ttagtattaa
    17281 aaacccatat gtaaatacaa tcaaacaaaa cttttcttta tcatttgagc aagctttaga
    17341 tttaaagaaa gtaattgaat ttatatatga tattagaata aatgatgatg aatgtgctta
    17401 tatagcatta cattttgaag cttttagaga aagaatgaaa gaacttccac aaaatattag
    17461 agtaattcta gtatgcagta caggattagg ttcatctagg ttattgtctg caagaataaa
    17521 aaaatacttt ccaatgataa agattgaaaa agtactttcc gtacaagaat tagtatccag
    17581 taaaattgat gcagatttag taataagtac tatttattta gagttagaaa caattccaac
    17641 catagtagtt agccctattt taaatgaaag tgatataaga accttggaaa gaaatataca
    17701 aaatgtttca tgttgtactt ctaagaagta taaatctttc agaaacctaa tctttgaaga
    17761 aaatatattg ttaaatattg aagcttcaaa ctatgaagat gcaattaagt atataacaga
    17821 taacctaata aaaaaaggtt ttgtaaaaga aggtatagct aaaagtgcaa ttgagagaga
    17881 aaatttatct tacacgtctt ttcagtcaat agctacacct catgctaatc ctagttatat
    17941 taaaaaatct aatatatctg ttgcaacgtt aaaaaatcct attacatggg gaaatgaaaa
    18001 ggtggaagtt attttcttta tttcattaga aaatgacaaa aacctagagc ttgatgaaat
    18061 atatgaagtt ttttatgact ttattgacaa taaaaaaaat ataaatgaca tattaagtgc
    18121 aacttccaca aaggaagtgt acgatttgct attggaggag agtatatagt gaaaatatca
    18181 gatgtattga aaaaagagca aattgttttt aatcttgata caaatacaaa ggaagaaaca
    18241 ataaaaaaat taagtagtat atttgttgaa aatgggattg tggacaatga agaagaatat
    18301 gttaagtctg ttttggaaag agaagaacat tcaactacag gtattggtaa tggtattgct
    18361 attcctcatg gaaaaagtga tgctgtcaaa aaatcttcta taatatttgc aaagactaag
    18421 cataagattg agtgggatgc tttagatgaa aaaccagtag atagtatttt cttattggct
    18481 ataagcaata ttgataagga tagcaatcat cttgtactat tatctaaatt agcaactaaa
    18541 cttatggatg atgacaatgt agatgcacta aaattagcca attcagaaca agaaataatc
    18601 aatatattta gtgaagaagg agagatgtag aaatgaaaag aaaaattata gcagttacag
    18661 catgtgcaac aggagttgca catacatata tggcagctca agcgttaaag aaagcttcaa
    18721 aaaagatggg tcaccttata aaagttgaaa cacaaggagc tacaggaatc gataatgagt
    18781 taactacaaa ggatgcacaa attgcagaag tagtaatatt tgcagtagat actaaagtca
    18841 gaaatgctga acgttttgag ggaaaagaaa tactagaagt accagttaat gcacctataa
    18901 aggatgcaga gaaagtaata aatgatgcat taaagttaat tgacactaaa taaatggagg
    18961 gaaatgtaat gttgaaaaag atagtctctg agttaaaaaa gcatgtctta actggaatct
    19021 catatatgat tccattagta attgcaggtg ctatgataat ggcaatatct cgtgtaggtg
    19081 gttctttcta taatatacca gatatatggg atgctaaata cgcagaaagt gctagtagta
    19141 ttgttagatt attacatgat ctagatggat ttggaggtac tgcattagga ttaatgtttc
    19201 ctgtaattgc tgcatttata ggattttcta tagctgataa attagctatt gtaccaggtc
    19261 ttgttggagg tatgattgct aaagatatag gtgcaggatt tttaggagct ttggcagttg
    19321 gtcttatagc aggatataca tgtttgttta ttaaaaatca tgttaaatta ccaaaatcag
    19381 cagcttcaat agtaccaata tttatagtac cagtatttgg aacattaatc actgttgtat
    19441 taatcaatta tgtgataggt ataccttttg ccacattaaa tactggatta gaaaattggt
    19501 taaatggatt atctggtaca aatcagatat taatggcagc tattataggg gctatgatgg
    19561 cagttgactt aggtggacca gttaataaag cagctttaac aacatcactt gcattattaa
    19621 caagtggaat ttatgcacct aatactgctg caatggtagg aatagttata ccaccactag
    19681 gattgggact tgctactata ctagcaaaac aaaaatataa taaacagtta cgtgaagctg
    19741 ggaaatcatc tcttataatg ggtttaattg gagtaagtga aggagcaatt ccttttgcgg
    19801 tagaatctcc attaaaagta ataccttcat gtgtaattgg aacagcaatt gcttcagcta
    19861 tggcagttgg tttaggttca gtaaatgcaa ctccaattag tggattttat ggatggttta
    19921 cagtagagaa ttggccaatg tatgtgttat caatagcagt tggaacagta attgtagctg
    19981 gattagttat agtattgcgt ggaaatccag tgattgagga tgatgaattt gaagatgatg
    20041 attttgatga agcagagtgg gaatcttaaa atttaataac tatttaagac gtgttataag
    20101 ctatattcaa tatgaatctt atactaaata aagtgttaaa tattcagttt agacttaaat
    20161 ataaaagata aagaacagag gagaataaat gataaaagca catattgtta atcatacaca
    20221 ctgggataga gaatggtatt ttacttctgg agatgcatta gtacttagtg aacaactatt
    20281 tacagatgta attgatgaat tagaacgtaa tccagatgta agttttgtac ttgatggaca
    20341 actttctatt ttggatgatt atgtacaatt acacaaagaa aaaatagaaa tcattaaaaa
    20401 gttaataaaa gaagatagac tacatattgg accatggttt actcaaactg atgcattctt
    20461 tgctagagga gagtctattt taagaaactt aatgattgga atttttgaaa gtaaaaagta
    20521 tggtaagtat atgaaaattg ggtatttgcc agatacattt ggatttaatg cacagatgcc
    20581 tatactatta aagcatgtag gtcttgataa tatattcttt tggagaggta tacatcttgg
    20641 taaacatgtt caatcaccat attttaagtg gaaaagctta aatggagaaa gttatatata
    20701 tgcagtaaat atgccacatg gatatggaac tggtatgctt ttagagcctt cattaaagta
    20761 tgttaatgga cgcttagacc cagctattga ttttattaaa tcatatactg atgtagatga
    20821 ggtgttaata ccttctggga atgaccagtt aaatataata ggtgatttca aaaataaaat
    20881 taaagcgatt aatgatatcg gaaagtattc atatataacg agttcatatc aagagttttt
    20941 aaaatatata aagtccatag aatcactaga aagctataga ggtgaattta gagaacctgt
    21001 attagcaaga atacataaat caattggttc tagtagaatg gatataaaat tagcatgtga
    21061 taaactagaa aacaagctga ttaaaagaat agagccatta ttagtaattg ctaaaaagag
    21121 taaaattgaa ataagcaatc agttacttat aaatacatgg aaaaaacttt tggaaggaca
    21181 agcacacgat agtctagctg gatgtgtaac tgatactgta acagattata ttcttcaccg
    21241 tataagagaa gcaaatgaaa tatgtgacag tattgaaaat actattgtaa aaaagatttc
    21301 agaagggctt aaattatcta aaaatgatat tttagtattt aatacagaag ctaagcgttt
    21361 taatggatat aaagagatac aagttgtaag tgatagtaaa aatatttatt ttaaagataa
    21421 tttagatgct actataattg aagaaactta tgtaaaaccg agagaaaatg tattagaaga
    21481 aacacctgct ggcaacgtat ttattgaaga atcaggatat tatatattaa aagtaagaat
    21541 aaatgtacag cttcctgcac ttggttataa agttgttagt tttgaatcaa gtgataaaga
    21601 aatggtatca cttgataaat ctaatgacac ttttatatct aatgataatt ataagataat
    21661 ctatgaagat ggaagcttaa atttacaact taaagatgga acttacatat caaacttttt
    21721 aatattaaaa gatagtggta atgcaggcga tacctatgac ttttctccat taaaaaatga
    21781 cgaggatata aaactttcat ttgatagagt gtatacagaa aaaactttag gatatgaaaa
    21841 gttggtggtt aaaggtacta ctttactacc acttacatta gaagatagaa aaaacaaata
    21901 tcttaatggg aaattaaatg taaaagtaag tattgtctta tccaaagaaa atccattgat
    21961 ggatgtaaaa ctttgtgttg ataacacgat atataatcat agactacgtg ttcatataaa
    22021 aactgatata aaagataata aaaacatagc atcattgcca tttggatata taacaagaga
    22081 aaatggagtt ttagacaact gggaagatat ttacagtgaa atgcctatag atttagaacc
    22141 tttggaaagt aatattactc taacaaacca aaatagaagc tgtactgtat ttactagagg
    22201 aataaaagag tatcaacata ttgaagatga aattgcattg accttacttg ctactacaga
    22261 tgaactagga aagcctgatt tattatatag accaggacgt gcttctggtg atacaactaa
    22321 aaaaggtcat ataagaatta aaacagataa agctcaaatg cttaagaaat tagaattttc
    22381 atttgcaata tatatggatt ctaaatcatt tgatgaattg gaaattgcga atttaaccca
    22441 caattatcta agggaatgtg taaattatca attacaggat tacaatttct ttttatatcg
    22501 tatagataat aagattcaaa aatcaattgt caataaaact gtaagtagag aattagaaat
    22561 aatatcttta ccagaaaaat atcttatatc agcatgttat ccttcttatt acagtaaaga
    22621 taaatttata ataagagtgg aaaatccaag tagtaataga atgatattgg atgagcaaat
    22681 atttaaaaat agaaatggga aaattgtaaa tgcaatagaa gatgtagaag aagaacaggt
    22741 atatgaaata gcaccttttg acgttatttc aatattattg gatttataag tgtaaaagta
    22801 agtttattgt ttaaagtctg acagatatta atctgccaga ctttttaatt tgtataaatt
    22861 tgggtaaata ttaatgaata gttttagtat ttaaatatga atttagtatt taatatagaa
    22921 tttattgaag tagaataatt agtttaacag gataagcagt ttaaataaag aattattata
    22981 ttagagtgat tttatatata atttaaaata ataaaatgtt aataaaatga gttaaagatt
    23041 gtatattaat agggttgatg tagttacaaa aaagttacca attgttatgt atttacaaaa
    23101 ctgatatatt aattacataa aatctaaaat agtttgtaat aggagtatat ataataaaaa
    23161 ttttaattaa ataaagctag gtatatttat aatattaata aatatattgc tataaaagtt
    23221 tgtttaataa attaaataaa gaaaagagga gaataaaatg tacaacatag atgatatgat
    23281 atataattgt ccagtagaag ctttatcaaa tattttaggt aaaaaatggg tggctataat
    23341 tatatggaaa atacaagaag ataagaaacg atttggagag ctacaaagag ctataccaga
    23401 ctgtagtaag aaaatgttag ttcaacaact agatttttta attgaacagg ggattatagt
    23461 caaccaaaaa aagttggtta ataatgttgt agagtcaaca tattttttaa gtgaatcagg
    23521 attacgattg cttcctgtca tggaaaaaat gattatgtgg agcaataaaa atttaaattg
    23581 tgataaatac taaaatttac tctgtaagta atgaaaattt aattaagcta tgagtagaaa
    23641 aatgtattaa aattacataa ttttttagtt agattttaat ttagaaatgg gattgtaata
    23701 ttggaaataa aataaggagg aattttaatt tgcaaaatgt aaatttattt ttagtattta
    23761 tagaaggtat agtatcattc ttttcaccat gtatactgcc aattttgcct atttatttga
    23821 gtatattgtc aaatagtagt gtagaaaatc taaaagaagg aaagacgagt tttataggaa
    23881 gttctttatt taaaaatact atattttttg ctcttggaat ctcaacaaca ttctttatat
    23941 tgggttcatc agtaaaagta ttgagtatgt tttttaatga aaataaagat ttaataatgt
    24001 ttattggtgg gattataatt attatcatgg gattatttta catgggaata attaaatctt
    24061 caatattgaa tagagaaaaa agatttaatg ttaagtttaa agaaatgaaa gcaataacag
    24121 cttttatatt aggttttacg tttagttttg gatggacacc ttgtattggt ccaatattgg
    24181 catctgtatt agtcatggtt tcaagttcaa gtaatcatct tagtgccaat cttttaatag
    24241 cagtatatac tattggtttt attttgccat ttataattac agctatgttt tacagtaaac
    24301 tatttaaaac tatagataag ataaaatcta acatggaaat tattaaaaaa ataggtggga
    24361 ttatacttat agtatcagga atattaatga tggtaaatgg atttggaagt ataagcaaac
    24421 actttaatac gtcacaaaat agcaaaattg aaagcaagca agaagaaaat aagcgagaaa
    24481 attctactga taaagaagaa aattctgatg gtaataatag tcaaaaagac tctaataatg
    24541 acaataatga taacgggtct aatgatgaag atagaataaa gtctattgat tttactttaa
    24601 cagaccagta tggtaaaaca cataaattaa gtgattatga aggcaaagtt gtattcttaa
    24661 atttctgggc tacatggtgt cctccatgta aagaagaaat gccttatata gaacaactgt
    24721 ataaagacta taataaaaac aatgatgatg tagtaatttt aggagtagct tcacctaatt
    24781 taggtagaga aggttcaagg gaacatgtag ttaacttctt aaaagaccaa ggttatacat
    24841 tccctgttgt acttgatgaa gatggagcat tagcatatca atatggaatt aatgcttttc
    24901 caactacatt tataattgac aaggaaggat atgtaactca gtatattcca ggagctatgg
    24961 ataaggcaac tatggcatca tttattgaaa atcagagaaa taaataaaag tatttaagta
    25021 tatgtttatg aatcaattta aggttacaaa aaagtgccta attgtaccac ctaaataatc
    25081 ttgttatagt aaaagtataa acaatacaag aaagggttga attttatatg aaaaaaacat
    25141 ttgatgctat aataatagga tttggaaaag gtggaaaaac attagcagga gatttggcaa
    25201 acaggggatt aaaagtagct ttaatagaaa agtcaaacaa gatgtatggt gggacatgtg
    25261 taaatgtggc atgtatacca acaaaaagct tagaaaattc agcaaacagc gtaaaaacaa
    25321 agaatataaa ttcttgggat gaagtacaag ctgaatatga gaaagctata gataaaaaag
    25381 aaactttaat tacaaaactc agagaagcta actataataa attaaattca aatgagaatg
    25441 taactatatt cacaggaatg ggaactttca ttgatgaaaa aacagttcaa gttaaaactg
    25501 aaaatgaaat ttatgagtta gtagcagata atatatttat taatactggt tcaagaccat
    25561 ttatacctaa tattaaggga attgaaaata agaatatagt atatgatagt gagtctctta
    25621 tgaatctaag agttttacct aaaaaaatga caattatagg agctggattt ataggtttag
    25681 agtttgctgg tatttatagt tcatttggag cagaagttac aatattaaac tctaataatg
    25741 gcattttacc aaatgaagat gttgaggatt cagaagaaat aataaaatta cttgcaaaga
    25801 gaaatgtaaa aattgttaat aatgcaaata taaaagagat taaagaagtt tctgaatcag
    25861 caatagtaga atatgaagta gatggtaaat ctaaagaatt aacaagtaat atgatacttg
    25921 tagctacagg aagaaaagca aacactgaag ggctagggct agaaaatgca ggtatagaat
    25981 taaatgaaag aggatttatt aaagtctcag aaactcttaa gactaataaa gagcatatat
    26041 gggctatagg agatataaat ggaggtccac aatttactta tatatcattg gatgattatc
    26101 gcatagttat taatcagtta tttggagata agactagaac aactaatgat agaaagaata
    26161 tcccaaattc tatatttata agtccagcat tttcaagagt tggtcttaat gttaaacaag
    26221 ctaaagaaaa gggatatgaa gtattagtgg caaagatgcc agtagaagca attccaagag
    26281 ctaaacagat tggcaaggca gatgggttta taaaaatagt gatagataaa aaatccaata
    26341 agatacttgg agctagtatg atatgtgaaa attcaagtga gattatccat cttattcaat
    26401 tagctgtaga tttagaagta gagtatacat atttaagaga ccgtgtttat gcacatccaa
    26461 ctatgacaga agctcttaat gatattctat ctcctaatat gataaaagaa gtataacata
    26521 agtttaatat ataaacctaa aattatcatt ataagtagat tttagaaaga ggctatctca
    26581 aaaaatagag ataagtctct tttttacttt ttaaatgata aaaatatatt tgattttata
    26641 aaagaagatt atcttatgaa ctaaaaagtt tattttaaaa cactacctat ttatgttata
    26701 aacttataaa tataatatag aatctattat tctgtattat taagtgaggt taagcgttat
    26761 aattaattat aaatattgaa taatctaaat ggataagata atggtattaa aaattatctt
    26821 aaaaggtgaa ataatctgta tttaatgtag tacagttata tctttaaagc aaggtggtga
    26881 aatgatataa ataagatatc taaaagaggg tttgatgata gtgataaaag atggttttca
    26941 agtaaagaat taacaagact tataaaggct aaagaagaaa tagaatggtt attaaatagg
    27001 gattacaaaa tagacccagt cgttactttt gttggtgata gatatcagtt ttctataaga
    27061 caaagagatg cattaaaaag agcagtctgt actgatgaaa aaaatattat aagacaatca
    27121 aaaaggcttt ttctagataa aatcaaagaa gataccgtaa atatagatgg ctttaatttg
    27181 ataatatcca tagaggtagc attatctggt ggtactctag taataggaag tgatggaaat
    27241 ataagagatt tagcaggtct taggggaacc tataagatta tagataaaac agaagaagct
    27301 ttgaatctga taggtaaatt ttttaataaa tacaatgcac agaatcttaa attttattta
    27361 gatgctccag tttctaattc aggaaattta aagtatagga tattagagca tgccaaaact
    27421 tggggaattg aaactgaagt agaattagta aaaaatgcag atgttgtatt ggaaaaatta
    27481 gatagagtag ttagtagtga tgcagtcata gttgacaagt gtataagtta ttttaatgtg
    27541 gctagaggta taattgaaga gtatattaaa gaatgtaata tcataaattt aaataaatag
    27601 ataaatagag gtgagaatat ataagtatat gtagcaatat tattagtaat acaagtaaag
    27661 tttgaaaata ggagaacgaa tacatatcga atttcataaa atgttgtaaa aagacatatg
    27721 agaggatgga tatgtgtgaa attaactaaa ctaaatatta aaaaatatag agcacctata
    27781 tataaatatg ctttagcaaa tgtaaatttg aggtctgcta aatctactaa ttcaagtatc
    27841 ataacagtaa tacctcaggg agctaaaatg gaagtattgg atgaagaaga tgactggatt
    27901 aaggtgatgt acaattctca agaaggatat gtgtataagg atttggtatc agtaagcgaa
    27961 tatgcttgga gtaacttaaa cttaagagaa gataaatcta taacttccaa tataattaca
    28021 gtaattcctg aaaaatctag ggttgaagtc cttcaagtag atggagattg gagtaagatt
    28081 gtatatgatg ataaaatagg atatgttttt aattattttt tatcaactga tgggaataaa
    28141 ccaaatgaat tagattataa gtatttttat actgacatga ttaaatttgt taacgaaaat
    28201 aatattaaaa gtactagcga ttatctaatt gtaacagacc ttagaaataa atatacttat
    28261 atttttaaga aagataatgg aggctggggg caactttaca agtggcaatg tactataggc
    28321 aagcctgaga ctccaactat aacaggtata ttttatataa gtggaagaaa accttctttt
    28381 ggaacggatg agtattcagt taagtatgct actagaatta aaggtggata ttactatcat
    28441 tctgtgctat atgattcaac aggaagttat ataatagatg gcagacttgg tgaagctctt
    28501 agtcatggat gtataagatt aagtacggaa aatgcaaagt ggatatatga taatatacca
    28561 gatacaacaa cagttataat tcattaagaa aaattttgag tttttattgg gataatgatt
    28621 ctcaaattaa taggattata tattaacttc ttcataaaga gtactattta aaaagtgtaa
    28681 taagagagtg ctattaacaa aacaaagata ttttgaggca ctctcttata aatatacata
    28741 attaagatat tttcataaac aattctataa tcttctcctt atcaaagaaa acaggattag
    28801 caccagcaca agcatctttc atagagtttt ctgcaagcaa ttcaaaatta ggattatcaa
    28861 cacctacatc ttttaaagat tttgggattc caacctcttc agaaagagct tttatcttat
    28921 ctattacaaa gtcaacacac tctttatctg atttattatt tacatccatt ccaataactt
    28981 cagctattgg tcggaatttg gcaggggctg atttagcatt ttcctcctca actattggaa
    29041 gtagcatggc attacatact ccatgaggta aatcatataa acctcctaat tgatgagcca
    29101 tagcatgtac atttccaaga cctgcattac taaaggcaat tccatttaaa aaacaagcat
    29161 aacacatttg ttctctagct tctatgtcat taccattttt aacagctctt ggaaggtatt
    29221 taaatatctg ctttatagca tataaggcag ttgaatctgt aacatcataa gcaccattag
    29281 ctactacagc ttctacagca tgagttagtg catccatacc agttgctgct gttaaattag
    29341 atggtttgct aatcattaat tctgggtcat ttactgtcat tgtagctagt gagttggtat
    29401 caaccattat catctttaca tgtctgtctt catcagttat aacatagttt attgtaactt
    29461 cagcagatgt accagcagta gtagttatag ctacgatagg aagacatttt ttagaagttt
    29521 tgttgatacc ttcatagtct ctaatatctc ctccattagt agctaatata gagatagctt
    29581 taccacagtc ttgtggagaa cctcctccta tagttataac gaagtcacaa ttttctgatt
    29641 ttaatatttt aagtccttta tccacattag ttacggttgg attttgttta acttcatcat
    29701 aaacaacaaa gtctacatct atctgagata aaatatctgt tacttttttt acagtaccat
    29761 ttgaaactag aaatttatca ctaacaacaa atgctttttt agttcctaat gatttaattg
    29821 aatctttagc ttcattaaga catcctttcc caagtaaatt tattggtggt acataataag
    29881 tgctcataac taaaatctcc ttttattttc attgattttt atgtaaaaat atatatctaa
    29941 caattttcac taatttactc ataatatatc gtatcttaga ttgagatagg gttactggtt
    30001 cttatataag aacttaattc gtaattacga ttatgattag aatttaacat agtattttta
    30061 tcatgtcaat aaaaatataa aaaatattat aaaaaaaaca aagttactgt agttaaatca
    30121 gcaactttgt ttttatagta taaatcaaat aaatacatta gtttaaaaca aaatttttaa
    30181 ttattatgtt ttgatatctt ccatatacag aatattaatc taatttatta caatgtcttc
    30241 attacgttct tccatcattg attgaatatt tttctgagca tttaagagta atttttttat
    30301 cagttctatt ttttcgtcat tagctctaaa taaaggcagt gttacactaa cagcagctct
    30361 tatacatcca ttttttctta ttggtacggc aagacatttt aggtgttcca ttgattcttc
    30421 acactctgaa gctatttgtg ttctttgaac ttcaagaagc tggtcgtata aaacatcaaa
    30481 atctgtaatt gatttttctg taaaaccttt tagaccatct ggatataagc ttattagttt
    30541 ttccttgtca aaatcacata aaagagcttt tccaagacct gtacaattag caggtatttt
    30601 ttttccaaca taagaaataa gtctaattgg ttctggagaa tctacttttc caatataaag
    30661 aacttcatta ttgtcaagta taccaagctg acaagtttca gaacaggaat taactatatt
    30721 agtcatttcg tcaattatat agttaaaaat agttcttttt tcaaaaaatg aagaccctaa
    30781 tgtgtaagaa cgtatcccta tagaatattt ggatgtgttt ttatcaatag taatgtattt
    30841 tctagcatta agtgtatgaa ctataggaaa gatgctactt tttggagcat tgataacatc
    30901 tgctatttct gtaagagtat atccattttc ggattctgct aatgcttcta aaatatctaa
    30961 tatcctagct gttgggcgat gattatctga agtcataaat ttccccctct ttttattaat
    31021 ttaaagtatt agaatatgtt gattttagca cactatacga tattttacaa tgtagaaaat
    31081 aaatatgtaa atttatatat aaataagctc ttgatttaga tacagataga tattttttta
    31141 gactgtacat taaggaataa ctaatttcca aaatatacct aaagaaagta agtgatattt
    31201 agttatataa tttaagtaaa tatatgcaat agttattttt atatgtaaat atcaaaatat
    31261 tatgaattta tattttatct attttttaca ctgtataaaa actttatagt tttgaatact
    31321 atataatttt aaatacgctg tatttttgca tataaggaag tcatttgata atatacaagg
    31381 tattatcaga aagtttgaaa aaaatttgac aaaaatttat tttttttatt gactcataaa
    31441 taggaaaatg ctatcattaa ttcaaagatt cgtaattaaa aacttagttc ttaaatacga
    31501 accgaaacgg ccgttagaat taaagctaaa aacttaataa gagtaattaa atatcatgtt
    31561 ttaggaggat taactttatg ataatggatt ttattaaaaa aattcctgca ggtatgatga
    31621 tagtgccaat gtttatagca gctttcatta ataccttttg cccagatatt gtacaaatag
    31681 gttcgtttac gacagcagta ttttcaagtg ttgggtctgc aactataatt ggggttcaac
    31741 tggtatgctt gggaactcag cttcaattta gagaaatgcc aaaagtttta aagagaggtg
    31801 gtatacttct tggttctaaa tttgctatag gtgctttgat aggtatactt ataggaaagc
    31861 tatttggaat ggatggtgtc cttggtctta caacattggc tgttataagt gcagttacaa
    31921 atagtaatgg tagtatatat ctttcattga tgacttcata tggagatgaa acagattgtg
    31981 caactatgag tttacttact ttaaatgatg gaccattttt tacattaata gctcttggga
    32041 cttcaggtct tgcaaatgtg ccattgttgt cattattagc tgcaatagtg ccaatacttg
    32101 ttggtatgat aataggaaat tttgacaaaa aaatgaaaga gtttttagag ccagggtgta
    32161 atttactcgt accttttgta gggtttgcac ttggtagtag cataaatctt gcaagtatac
    32221 taaaaggagg tttatcagga gtattacttg gattaatatc tgtatttgta ggaggtatat
    32281 ttatagtatt ctgtgataaa tttataggaa aacgtccagg atatgcagga tgggctgtag
    32341 ctacaaccgc tggaaatgca attgctgtac ctgctgctgt tgcattagtt gacccatcat
    32401 ggcaaccata tgttgcaaca gctacaacac aagtggcagc cgcagtagtt gtcactgcaa
    32461 tattagtacc tcttataact agttggtggg ctaagaagta tggatgtcct aagttcccaa
    32521 aacaaaatga ggatggtaca ataacagctt aatttatatt acagtgagtt gttggtaaaa
    32581 taataaattc tttaattaga ttttaggata ttaataaaat tatattattt ataaaggaga
    32641 gcaagaataa tgataaatgc agtgataatt gatgaaaaag ataatgttgc agtagctatt
    32701 gaagcaatag ctaaaggtaa tgaaattagt tttaaattaa aagacaaaac agtaaaaacg
    32761 attacagcac tagataatat aactatttat cataaattgg ctataaaaga tatggcccaa
    32821 ggtgataaag ttactaaata tggtgaacat ataggagaag caaatcagga aataaaaagt
    32881 ggtcaacatg tacatattca taatgttaga agtgttagag aggatttgga taaacaagtt
    32941 atgactaata tataaaataa tatttataga gttataaaag ttgtattcat tgcttttagt
    33001 gtcaaatagt ttttaaatag gattttagct gtttgattag tgagtgtaat aaaaattata
    33061 atatataaaa attataaaaa gtatatagac tattttagga ggaaatcagt atgaaatttt
    33121 atggatataa aagaccagat ggaagagttg gtataagaaa ccacatatta atattgccta
    33181 cgagtgtgtg tgcatcagat acaactagaa taatagcatc acaagttcaa ggggcagtta
    33241 cctttaataa tcagaatgga tgttcacaag tacattcaga ccaacaatta actatggatg
    33301 ttatggctgg ttatgcagca aatccaaatg tatatggtgt aatagttgta tctttgggat
    33361 gcgaaaattg ccaaaatgat ttggtagttg atgcaataaa agagagaaca aataagccaa
    33421 taaaaactct tgtaatacaa gaagaacatg gaactttaaa aactatagaa aaagctgttc
    33481 gttatgctag agaaatggca caagaagctt ctttgcttag aaaagaagaa tttccaatat
    33541 ctgaacttat actaggaact gaatgtggtg ggtctgaccc aacaagtgga ttagcagcaa
    33601 atccattaat aggtgaatta agtgataaac ttgtcgattt aggagcaaca tcaattttaa
    33661 gtgaaactac tgaatttata ggtgcagagc atatactagc taggagagca gtaaatgaag
    33721 aagtaaaaga aaaaatatta catatagtac atagatatga aaattcatta aaattggttg
    33781 gagaagaagt tagagaaggt aatccatctc ctggaaatat agctggtggt ttaacaagtt
    33841 tagaagaaaa atcacttggt tgtatacata aaggaggtca tagacaaata agtgaagtat
    33901 atgattatgc caaacaaatt gataagaaag gtcttgttat aatggatacc cctggaaatg
    33961 atgcttcatc tgttgctggt atggtagcag gaggagcaca aatagtggta tttagtacag
    34021 gaagaggaac accatcagga aatccaatag caccagtaat aaaaataact ggaaataaaa
    34081 taacttttgc aaatatggaa gataatatgg attttgatgc tagtccagtt atctatggtc
    34141 cacaaacaat ggaagaatta acagatgatt tgttaaatat ggttgtagat gtagcaaatg
    34201 gaaaacaatc aaaagcagag tcccttggat atactgaaat ggcaatagct agagtatgca
    34261 actatgtata atctttaagt aagaaaataa atacatagaa ttttaataaa gggtgagatt
    34321 atgaagtttg taagttttac tgaaggagaa aatgaatgta aaagaactgg agttttttct
    34381 aaagatgaat tatttattat agatgttaac tctttaaatc tcagtagaaa ttttaaggat
    34441 ttaaatgaat taattcaaaa tgtatctagt gaagatatta ttaagttgaa aactattata
    34501 aatgaaagta tattctataa ttatgatgtt tttaaaagag agagatgtac tgtacatgtt
    34561 cctatagaaa aaccaataca tgatatctta tgtgtgggag tgaactataa agaccatctt
    34621 gaagaaactc aaactcactt tgatgatagt tttgaagagc cacaaaaaac ggtttatttt
    34681 acaaaacgtg tgacaaaggc aataggtcca gaagatgaga tagatggtca ttttgagata
    34741 aataatcaac tagactatga agttgaactt ggagtagtaa taggtaaaac aggtgttaat
    34801 attagaaaag aagaggtaga agattatatc tttggttaca ctgttataaa tgatatttct
    34861 gctagaaagt tgcaaaaaga acatgttcaa tggtttagag gaaaaggatt agatacattt
    34921 acctctttag gtccatgtat tttacataaa agtgcagttc cttttcccat aaaacttaaa
    34981 gtatgtagta gggtaaatgg tgaagaaaga caaagttcta atacaggatt attcatatca
    35041 gatgtttcag acatagtttc agaactttca aaaggtatga ctttagaggc tggagacatt
    35101 atagctactg gaacaccttc tggagtaggg atgggatttt cacctcctcg atatatgagt
    35161 agtggagatg tagttgaatg tgagattgag agtattggaa ttttaaaaaa ttacattaag
    35221 taaatgtttt aatataatta atattaaagc taaatctgat gtattaatga acatattaaa
    35281 ataaatttta ggagtttaaa ttatgaaagc agaatttttg acaccagttg ttacaatatt
    35341 tgatgaagaa ggaaatttag ataaagaagg taataaaaaa gtgtacgacc atcttataga
    35401 tggaggtgta gatggactag tcataatggg aagtactgga gagttcttta atatgtctat
    35461 ggatatgcaa aaagaactta tagatttagt aactagtcat gtaaataaga gagtaaaagt
    35521 gtttataggt acaagtcgta tgtgtataaa tgaatctata gaactttcaa actatgcaca
    35581 taatagtgga gcagatggcg ttatgataat aagcccttat tatttctctc ttgatgatga
    35641 tagtattgag ttattttata gtgaaatagc taagaataca gaggctgaaa tatatttata
    35701 caattatcca gatagaactg gttatgattt aagtccagaa cttacattaa gacttgcaag
    35761 aaaacataaa aacatagttg gatataagga tacagtaact ttgatgggac ataccagaga
    35821 tttaataaat actatgaaaa tagagttccc agaatttaag gtttatagtg gttatgatga
    35881 aaactttata cataatctaa tgtctggggg agcaggttgt atagggggat tatcaaattt
    35941 aattccagaa gtttgctcca aatgggctga agcttacaat aatagagata tggagaaggt
    36001 tatagaaatt caaaaatata ttaataaagc aatggatttt tacttaataa ccaatccatt
    36061 tataccagca atgaaaaaag ctatgaatat cagagggtta caaataagtg attatatgac
    36121 tgctccattt gtaaaaccaa atgaaaaaca agtatgtgaa attaaaaaat tgatgaataa
    36181 attaaatata tgttaaatca accttgcaaa gaggtcaaca ataaattaca attatcttaa
    36241 taaaaattaa attaaaataa tactagggta ctatattagt ttaataggga aagtgatgaa
    36301 aattcactac agcccccgct actgtatacg gatacgaaat caaaatccac tgaaatttat
    36361 aaaaattttg ggaagggtga tggaggaaaa gccgtgagtc aggagacctg cccagtatta
    36421 tataagttca atttagggtg gagattgtaa tttataataa aatgaagtat caattcgttt
    36481 ttgtaaagtt gatatatgaa cttctcctta ttaaattagg agaagttttt tattttatta
    36541 aaaggttata cttattaaag atgactttag gataacttta ataagtatac tttaaaaagc
    36601 atatattatt aaagtttttt agccactcat aaaaaataag atattggagt gaaagagatg
    36661 aaatttaaat caaatgtttt aaagcagttt tttttaattg ctatggtaat ttttatggta
    36721 ggaggtctta tagggtgtag taaaagtgac aaagagaata aacaagctag tactggtaag
    36781 aaattagaat taaaatatgc tagtggattt agtgttgaag atttagaaga tggaattaaa
    36841 aaagtaactg atggagataa tcgagaactg attttaatcc caaagaagat taaaattcct
    36901 gaaaaatata aaaatgctaa tatagttaga acgcctgtgg acaatgtatt aatagcatct
    36961 acaacacagg cttgttctct gagaacaata gatgaactag atagtataaa agccgtaaca
    37021 acagaagagc agtactggac tattaaagaa attaaagatt taatgaaaga tggaaaaata
    37081 cattacgttg gttcaaattt agcaccagat tatgaaaaaa tagtagactt aaatcctgac
    37141 ttaactatag tgagtagtgg tttatcagag gctgatacaa aatttattga caaattaaaa
    37201 gaattagggc ttaattatgt tgtagacaat gagtataaag agcaaaatcc atttggaaga
    37261 atggagtgga caagtttaat agctgcattt tatgataaag aagatatggc tactagtgaa
    37321 ctaaataaaa ctgtacaaaa ggtagaagaa gtaagtaaaa aaataaaaaa caaagctaaa
    37381 cctaaagttg tatgggcatc tgtatatgaa ggaagtgctt atatagctcc taaagattca
    37441 tatgtggata atatgataaa aatggctggt ggaataaatg catgtgcttc aatagattca
    37501 aatgaagggc gagtaagtat tgaacaattg catgaagttg caaaagatgc agatatattt
    37561 gtatactcat caagttcaga ttatgcacca aatttagatt ctataaaatc tagtgcacct
    37621 gtattggctg atttggatgt tgtaaaaaac ggaaacctat gggtgtttgc tccagattat
    37681 tatcaatcag tagataagac ggacgaatta atagtagatt tagttgagat gttccaccca
    37741 ggtactacag gtgaaaaaat caaacattat ataaattatg ataaatagta cagagaggac
    37801 acaaaaagat aggttttata gattttagtt aatataactt tgctaagagg agtatacaaa
    37861 tggattttat caataaaatg agaataagga atacgacaat atttatagta ttaattataa
    37921 gtatgatact tactttttta gtgtgtgtag catttggctc tgtaaaaatt gaatttaaag
    37981 aagtaataga tgttgtatta agaggtatgg ataatacaga acattataaa ataatataca
    38041 atataagaat ccctagagta cttgcaacca tggtaggtgg agcatgccta gcagtatcag
    38101 gtattttatt acagatattt tttaaaaacc caatagttga accgtatata ttaggagtat
    38161 cttcaggttc tactttatca gtagctctca tgattttggg aggatacaca ttgggatttg
    38221 agagtgtaaa ttcaatgagt atatttgtag cagcttttat aggagcttta attgtaatgt
    38281 ctatagtcat tttatttgca aataaggtaa agaatataac aactctttta ataataggaa
    38341 ttatgaccgg atatgtatgt agtggtataa caaatgtgtt acaatcattt gcaaatagtg
    38401 ataaattaaa agaatttact atgtggtcta tgggaagttt ttctggattt acatgggaaa
    38461 aggtagaaat acttataata gttggtatat taggtctttt gatgactgta ttcataataa
    38521 aacctttaaa tgctttttta ttaggagaag agtatgcaaa aagtattggc ataaatataa
    38581 gattttttag agttttgata gtgtttatat ctagtatatt agcagcaata gtatcagcat
    38641 ttgcaggacc tatagggttt attggacttg cagtgccaca aatttcaaa
//
LOCUS       DAEQJM010000031        38207 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.031, whole genome shotgun sequence.
ACCESSION   DAEQJM010000031 DAEQJM010000000
VERSION     DAEQJM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38207
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.031"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..203
                     /locus_tag="KRQ43_002005"
     CDS             <1..203
                     /locus_tag="KRQ43_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH2742361.1"
                     /translation="SMESYNRLLRKVTKSKSIFPLDDSLHKSLYLATMDISERWTQKI
                     RNWTQILAHLSIYFEERILTLN"
     gene            complement(563..1717)
                     /gene="nagA"
                     /locus_tag="KRQ43_002006"
     CDS             complement(563..1717)
                     /gene="nagA"
                     /locus_tag="KRQ43_002006"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH2742362.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQRKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFSVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYVPALSCNIDNVCGSIHQGMDADFIVTDKNFNIYETYISGICMYKVNK"
     gene            complement(1800..2525)
                     /locus_tag="KRQ43_002007"
     CDS             complement(1800..2525)
                     /locus_tag="KRQ43_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2742363.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRIQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            2794..3723
                     /gene="pfkB"
                     /locus_tag="KRQ43_002008"
     CDS             2794..3723
                     /gene="pfkB"
                     /locus_tag="KRQ43_002008"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH2742364.1"
                     /translation="MITVITFNPSIDRMYKVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEYNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(3852..4769)
                     /locus_tag="KRQ43_002009"
     CDS             complement(3852..4769)
                     /locus_tag="KRQ43_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH2742365.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     ICSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVNQ
                     GEELIELSKKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKHFSVNTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            5231..6400
                     /locus_tag="KRQ43_002010"
     CDS             5231..6400
                     /locus_tag="KRQ43_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH2742366.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     NRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPQGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            6449..7300
                     /gene="gatY"
                     /locus_tag="KRQ43_002011"
     CDS             6449..7300
                     /gene="gatY"
                     /locus_tag="KRQ43_002011"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH2742367.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            7626..9527
                     /locus_tag="KRQ43_002012"
     CDS             7626..9527
                     /locus_tag="KRQ43_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH2742368.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASNLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            9530..10573
                     /gene="ypdE"
                     /locus_tag="KRQ43_002013"
     CDS             9530..10573
                     /gene="ypdE"
                     /locus_tag="KRQ43_002013"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH2742369.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            10588..10893
                     /locus_tag="KRQ43_002014"
     CDS             10588..10893
                     /locus_tag="KRQ43_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH2742370.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPTMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            10990..11325
                     /locus_tag="KRQ43_002015"
     CDS             10990..11325
                     /locus_tag="KRQ43_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742371.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            11357..12679
                     /locus_tag="KRQ43_002016"
     CDS             11357..12679
                     /locus_tag="KRQ43_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2742372.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            12689..13759
                     /locus_tag="KRQ43_002017"
     CDS             12689..13759
                     /locus_tag="KRQ43_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH2742373.1"
                     /translation="MNNTIERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            13764..14951
                     /locus_tag="KRQ43_002018"
     CDS             13764..14951
                     /locus_tag="KRQ43_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH2742374.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVANNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(15148..16020)
                     /locus_tag="KRQ43_002019"
     CDS             complement(15148..16020)
                     /locus_tag="KRQ43_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBH2742375.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVSYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYKQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLHLNPEVFKNDALIYTNIDEVSIYNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(16414..16605)
                     /locus_tag="KRQ43_002020"
     CDS             complement(16414..16605)
                     /locus_tag="KRQ43_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742376.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            16825..17871
                     /gene="cobT"
                     /locus_tag="KRQ43_002021"
     CDS             16825..17871
                     /gene="cobT"
                     /locus_tag="KRQ43_002021"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBH2742377.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            17903..18463
                     /gene="cobU"
                     /locus_tag="KRQ43_002022"
     CDS             17903..18463
                     /gene="cobU"
                     /locus_tag="KRQ43_002022"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBH2742378.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            18473..19246
                     /gene="cobS"
                     /locus_tag="KRQ43_002023"
     CDS             18473..19246
                     /gene="cobS"
                     /locus_tag="KRQ43_002023"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBH2742379.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWIIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            19266..19880
                     /locus_tag="KRQ43_002024"
     CDS             19266..19880
                     /locus_tag="KRQ43_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH2742380.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      19947..20126
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            20256..21755
                     /locus_tag="KRQ43_002025"
     CDS             20256..21755
                     /locus_tag="KRQ43_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HBH2742381.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVGVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            21794..23170
                     /locus_tag="KRQ43_002026"
     CDS             21794..23170
                     /locus_tag="KRQ43_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HBH2742382.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDASVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            23171..24142
                     /locus_tag="KRQ43_002027"
     CDS             23171..24142
                     /locus_tag="KRQ43_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH2742383.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYVSSFVSMLVFTLIHVLCRMILINLII"
     gene            24174..25244
                     /locus_tag="KRQ43_002028"
     CDS             24174..25244
                     /locus_tag="KRQ43_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH2742384.1"
                     /translation="MKDLGHGANVGEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIGINPDFIIPGNGATEVIYLLMKSVKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLGKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRAYKKTTKELKKDLLKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            25246..26133
                     /locus_tag="KRQ43_002029"
     CDS             25246..26133
                     /locus_tag="KRQ43_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH2742385.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSEVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVIILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKSMNDKKMIDTLCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            26121..26753
                     /locus_tag="KRQ43_002030"
     CDS             26121..26753
                     /locus_tag="KRQ43_002030"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HBH2742386.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            26762..27988
                     /locus_tag="KRQ43_002031"
     CDS             26762..27988
                     /locus_tag="KRQ43_002031"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HBH2742387.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCKERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            27985..28593
                     /locus_tag="KRQ43_002032"
     CDS             27985..28593
                     /locus_tag="KRQ43_002032"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HBH2742388.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNVVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKIPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            28583..29158
                     /locus_tag="KRQ43_002033"
     CDS             28583..29158
                     /locus_tag="KRQ43_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HBH2742389.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNIKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            29151..29903
                     /locus_tag="KRQ43_002034"
     CDS             29151..29903
                     /locus_tag="KRQ43_002034"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HBH2742390.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            29887..31008
                     /gene="cbiG"
                     /locus_tag="KRQ43_002035"
     CDS             29887..31008
                     /gene="cbiG"
                     /locus_tag="KRQ43_002035"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HBH2742391.1"
                     /translation="MNIEGNIAIICITENGKNLAVKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIIFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSIDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPIAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            31005..31730
                     /gene="cobJ"
                     /locus_tag="KRQ43_002036"
     CDS             31005..31730
                     /gene="cobJ"
                     /locus_tag="KRQ43_002036"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HBH2742392.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            31727..32479
                     /gene="cobK"
                     /locus_tag="KRQ43_002037"
     CDS             31727..32479
                     /gene="cobK"
                     /locus_tag="KRQ43_002037"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HBH2742393.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            32498..33976
                     /locus_tag="KRQ43_002038"
     CDS             32498..33976
                     /locus_tag="KRQ43_002038"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HBH2742394.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEEDGFDVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            34006..34911
                     /gene="hemC"
                     /locus_tag="KRQ43_002039"
     CDS             34006..34911
                     /gene="hemC"
                     /locus_tag="KRQ43_002039"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBH2742395.1"
                     /translation="MNIVVGTRGSTLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            34901..36400
                     /gene="cobA"
                     /locus_tag="KRQ43_002040"
     CDS             34901..36400
                     /gene="cobA"
                     /locus_tag="KRQ43_002040"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBH2742396.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEDIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDNDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEDKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            36417..37382
                     /gene="hemB"
                     /locus_tag="KRQ43_002041"
     CDS             36417..37382
                     /gene="hemB"
                     /locus_tag="KRQ43_002041"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBH2742397.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     NSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            37535..38113
                     /locus_tag="KRQ43_002042"
     CDS             37535..38113
                     /locus_tag="KRQ43_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HBH2742398.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCRAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        15227 a         4028 c         6784 g        12168 t
ORIGIN      
        1 attcaatgga aagttacaat agattattaa gaaaagttac taaatcgaag tctatttttc
       61 ctttagatga ttctttgcac aaatcattat acttagcaac tatggatatt tctgaaagat
      121 ggactcaaaa gattagaaat tggactcaaa tcttagctca tttaagtatt tattttgaag
      181 aaagaatttt aactctaaat taataaagaa atatttcaaa aaaattaagg aattttctta
      241 aaggggtaat aatttttaca aaaatggaaa aaatatcaaa ataaggctat gatttttaaa
      301 gccatagcct taccaataaa tgtttaatta tcactaaaaa ataaattttt attcaaagaa
      361 tacacataaa tatttccaga ttcttaattt tataaactta tattgtaaaa taaagaacct
      421 taataaaagg agtgtctcaa aattaacttt ttagtttatg aggcactctt tttgtatgaa
      481 atcaaatgta ttttcatcat tttaacaatg aaaaagagac ttatctctat ttttaggaag
      541 cctccataac tttatattga atctatttat taactttgta catacatata ccacttatat
      601 aagtttcgta tatattaaag ttcttatctg ttactataaa gtctgcatcc ataccttgat
      661 gtatggagcc acagacatta tcaatattac aacttaaagc aggaacatat gtagccattt
      721 ttattgcatc ttctaaagtg gctatgttcc aatcaactat atttctcaca gccttgtcca
      781 tagttaatac acttccagct aaactcccac tatttaatct tgcaacacta ttttttacat
      841 ttacactaaa cttaccaaga gtatattttc catcctccat agcaccagcc ctcatacaat
      901 ctgtaattaa agctatgtta ttactagact tcgcatccat cattatttta acagctattg
      961 ggcttacatg atgaccatca caaattaatt cagcataagt atcttttagt accatagcag
     1021 ccccaaccat tccaggttct ctatgattta aagggctcat cccattatat gtatgtacaa
     1081 acactttagc acctgaatta acgacttgtt taacttgttc aaatgtagct gaactatggc
     1141 caagagaaac agagatatta tttttagttg catatcttgt taattctatt gaacctttac
     1201 gttctggagc aattgctatt tttcttatta aatttttcga ttttctttgc cataatttta
     1261 atatattgat gtcagggtct ttaaaatatt tttcattttg agcgccctta tatttttctg
     1321 taaaaaatgg accttctaaa taaatccctt gtatttttgc accctcaact cgattgaagc
     1381 tattgcttat attttctaca gaatcactta gtgtatctac agaatcagtt aaagttgtag
     1441 gtaggaaaga tgttactcca tattttaata agccttttga aattgtgttt attgcttcaa
     1501 atgtattgtc catgacatct gcacctaaaa gaccgtgaat gtgagtatca actaagccag
     1561 gagcaatata tttacctgaa aaatctatga cattatcagt aatattaggt ctttcttgtt
     1621 gaaattcacc gaatttgcca ttaattatac taaggtaacc tttttctttg attccatgtt
     1681 tcataaaaaa tttatctgca taaataaaac ttttcaaaat aacctcctta taattatact
     1741 atcattgtgg cattgacgtt tataatatca ttctattttc ttgaaagcta tttaattcac
     1801 tatcttacat gtcttactct atatacaaat ttatcgcttc tagcaacact caaagtaaat
     1861 tcaataacta tattgtcatc attatatgtg gtacgaagta atttcagaca aggtgaatct
     1921 cctggtactt ccaataactt agcttcctta tcagagatta ttccagctga aaattcttca
     1981 tcagcaactt taataatctc gccataatct tctctaaata tttcatataa aggtttttgt
     2041 tcgatttttt cttttgtcaa tcctataaat tctttcatag gaagatatgt tctttcaagc
     2101 atcataggaa ggtcatcagc aagtcttaaa cgcattattt ttatcatttt ttcaccagga
     2161 gttataccta atttttcaga gaaatacttt gtactttcta ctacctcaaa tgataatacc
     2221 tttgtacctg gcttttttcc ttgtattctc atataatctg taaagctata actttccatt
     2281 aagttttgag aattttgact tagtgcagca acaaaagttc cttttccatg tcttttgtat
     2341 atatatccca tatgttccaa ctcagccata gctagtctaa ctgtggttct acttactcca
     2401 tattcatcac aaatttttct ttcagaaagc attctatcgt ttggttccat ctcattttca
     2461 atcttagttc ttaatatctc aacaagctgg tcatatattg gtcttttatc atttcttttt
     2521 atcataaaaa catagtcctt tctaagtggt tattaccaca atttgattat agaatataga
     2581 attatttatg tcaatgaata aagtttaatc aaaattcaat aagtaaggct attaatttat
     2641 tataaaatta tggtatattg acaaaacaag taaaataatt tatattcaaa ttggtaataa
     2701 ccactttggg tatattatag atgaggtatt ttttatttta cagattaatt tattgtttag
     2761 aaaagtaaaa attaataatg aggagaatct agtatgatta cagtaataac attcaaccca
     2821 tctatagata gaatgtataa agtgaataat ataaacatag gtgaggtgca aagggtagta
     2881 agtaagaatg caactgctgg aggtaaagga ttaaacgtag ctaaggtatg taaaatttta
     2941 aaagaaaatc ctttagctat gggatttcta ggtggattta atggagaatt tataaaaaat
     3001 gaacttagaa aactagatat acaaaataaa tttacaaaaa tagagcagga aactagaaat
     3061 tgcttaaaca taattgagga caataaagtt agtacagaat ttttagaaaa aggaccaata
     3121 gtagaaaaaa gcgatttaga gagatttgaa aatgatatag aggaagtact aaaaaatact
     3181 aaaatactag tagcttctgg tagttattgt gagaatatgc cgatagatta ttatgaaaag
     3241 ataggaaata tatgtagagc aaataatata aaatttatat tagatacatc aggagaagca
     3301 ttaaaaatag ctttaaaatc aaaaccatat ttaataaagc caaatataga tgaaataaga
     3361 catttattag gaataaatat agaatcaaga gaggaaatta tcttgtcagg aaaaaaactt
     3421 attgaaatgg gtgcagagaa tgtatgtata tctttaggaa aagatggtat ggtgtattta
     3481 aacgaatata atgtatatga tgtaaaagta ccagttgtaa agtgtataaa tactgtaggt
     3541 agtggagata gcacagtggc tggatttagt gtaggtattt taaggggtta taaaatagaa
     3601 aatttactta aatttgcaaa tgcttgcggt ataagtaatg ctttaaatat ggaaactgga
     3661 tttgtagatt tgggagaaat tgataaatat caagatttag ttgaagtaaa aaagttaagt
     3721 taaataaatt taatgggaat ataataaatt taatgttgtt gtaatagatt ttaattttaa
     3781 tataaaagat atagtcttat ataaaaatag gttagaaaaa ttcattttta acctattttt
     3841 ataataaata tctattttac tgaatttata attttctcta gtaatctttg agccttgata
     3901 cactcttctc cattaatagc tggttttata ttattttcta tacaatcaat aaaatgattt
     3961 gatatatcct caaaaccctt ttgttttaat atatttaccc atgcaccact ttgttttaaa
     4021 gttaggtttc caccttcttc tatttccagt acattaagat tcttaactct ttgaatctta
     4081 ccttttgaaa gaatttcaac ttgttctaac tttgttccag aatctctatg catagaggtg
     4141 tttacagaga aatgtttacc tttaagttta tgacttacaa atataagatt cttattgtct
     4201 gttaaaaata aatcttctcc gctaatttca acatcttcat ttgctaacca taaagcagtg
     4261 tcaataacat gtatatagtc atctataagg gtactgtcga atctaacatt tcttaaggaa
     4321 tttaatccat gtttacatat attgatagat acgatttctg tagcattatt tttaatttct
     4381 ttgtacatag gacagaatct acggttgaat ccaaccatta aatttaagtt ttttttctta
     4441 cttaactcga taagttcttc tccttgattt actgttgaag caagaggttt gtctacatat
     4501 acatgaacac ctaaatttaa taatattttt ataatttcgt agtgtgtttc tgtagagcta
     4561 tgtagaaaaa tacaatcaca ttttttagct agggattcaa tagaatcgaa tggcataatt
     4621 ctataatcac tacagatttt ttccctttta actttatttg gagtaaaagc tcctacaaac
     4681 tcaaatctct cagacttagt taatataggt aaatatgcct tttgagctat ggagccaaga
     4741 cctatcattc ccatttttat atttttcata atactttctc ctaaggtttt tatatttaca
     4801 gaattgatta taattcagac acataaattt gtaaactttg tatcaaaaaa taaatttaaa
     4861 gcttatataa gtaaattaac gaaataagaa atattgacaa agtaattttg taggatatct
     4921 ataaaattga ttgatataaa tattttatgt attgacaaaa aattcaaatt aatttatatt
     4981 tggattagtg gtaattacca ctttggtctg aacaagtttt tatcgtaaaa taaaaatact
     5041 aaagtatgat tttattaaat ttttaaagat aaactataaa attaattaaa atctatagcg
     5101 tatattttat agtgagttta agtagtacta aaaaatctaa gcaaaaaatt ataaaagagt
     5161 atattttttt atagtttaaa gtggttataa cctcattacc aaatgtaaac gttacaagta
     5221 tgaaaggaga atgaaaatgt ttaaattaga agaacaaaaa ctaaaagatt taggtgcaat
     5281 aataacaact aatgaaataa aacaacaacc tgagttatgg ttagagactt atgaaatata
     5341 taaatctaac aaagaaaaat taaatagatt catagataca ataagtaata atcatgggca
     5401 gtttagagtt atatttacag gtgctggaac ttcagcttac ataggaaatt caatacttcc
     5461 ttaccttaag aataaaaatg acataagaaa atacatattt gaagcaatac ctactacgga
     5521 tatagtttca aacccatatg attacttaaa aaaagatata ccaacattat taatttcatt
     5581 tgcaagaagt ggaaatagtc ctgaaagttt ggctgcttta aatttaggga ataagattgt
     5641 agataatttt tatcatttag ctataacttg taatccgcaa ggagaactag ctaaaatgac
     5701 taaaaacgac gaaaataatt acttgttatt aatgccatca aaatcaaatg atgaaggctt
     5761 tgctatgaca ggaagttttt cgtgtatgat gttatctgct atgttaatat tcgatagttt
     5821 agaagatgat gtagaaaagt catatataaa tgcaataatt gaaatgggaa gaaatgttat
     5881 agatagaaaa gatgaaatac atgagttaat aaataaagat ttcgatagag ttgtatattt
     5941 aggttcagga ggattaggtg gtttgacaca agaagcacaa ctaaaacttt tagaacttac
     6001 agcaggaaaa atatctacgg tgtatgattc tcctatgggg tttagacacg gaccaaaatc
     6061 atttattgat gaaaatacac ttgtatttga atttgtatct aactgtttat atacaagaaa
     6121 atatgattta gatgttttag aggagataaa aagggataaa attgctaaat tcacttgtgc
     6181 agtgtcagta gaaaatgaaa ataacttctc aggaacaaag tttgagttta aagaaaagta
     6241 taataaatta ccagatgtgt atcttgcaat gccatacata ttgtttgcac aaactatagc
     6301 attgtttgta tcggtaaagg ttggaaataa gccagatacg ccatcagcta caggaacagt
     6361 aaatagagta gtaaaaggtg taacaatata tgaatattaa aagataagat taaaatatta
     6421 taactaaata atttgggagg gtatcaatgt ggcattagta acaacaacat caatgcttaa
     6481 aaaggcacaa gatgaggggt atgcagtagg agcatttaat gtagaaaata tggaaatggt
     6541 aattgctgtt atagaagcag ctgaggagtt aaactctcca gtaatattac aaactactcc
     6601 atctactgta aaatatgcag gtcttgatta ttatctagca aatgcaaagg ttgctgcaga
     6661 aagagtaaag atacctgtag caatgcatct ggaccatggt tcaagttttg accttgcaat
     6721 gaaagcttta agaagtggat atacatcaat aatgatagat ggttctcatg aaagctttga
     6781 aaataatata tctatatcta aatcagtagt aaaagcatgt agtccttctc ttataccagt
     6841 ggaagcagaa cttgggaaag ttggtggaaa agaagatgat ttagatggcg ggaatagtaa
     6901 tgattataca aatccaaaag aggcaaaaga gtttgtcgat agaacaggaa tatcttcatt
     6961 ggctattgct ataggtactg cacatggatt gtataagggt gaacctaaaa tagatttaga
     7021 taggttatca gaaattaaaa atgtagtttc aataccttta gtattgcatg gaggttcagg
     7081 aatacatgat gatattataa aagaagctat aaaaagaggt attgcaaaag ttaactatgc
     7141 aactgaatta agaattgcat atagtaaagg ggttaaaaaa gttttagatg aagattctga
     7201 ggttatagac cctaaaaagt atggattagc agggcttcaa tcagtgaagg attttgtaaa
     7261 agaaaagatt aaagtgtgtg ggtctgtaaa tagagtataa aaataaaata tcctaaattt
     7321 attttagata agtttaggat atttgttata tgaaaaattt atattaatta tatgtaaatg
     7381 gtgtattttt ttcatttaat tgatgaaaaa tatcagcttt tattggtaaa gtattacata
     7441 tataattaaa atataataaa aattgaacta tatattttat tattataaaa tatgtatatt
     7501 aaattttgga atcaaaatat actaggatat aaaattctta aataaaaaga aaaggttgtt
     7561 tttataaaaa atatttttta taccacttta aaaaacacaa taataacact gagggaggtg
     7621 gggatatgag agaacgcatt attcttgaaa cattaaaaaa tagtagtggt tatctaaaca
     7681 tagattattt tgcagataag ttgggggtat ctactcgaac tatcagaaat gaaataaaaa
     7741 agatagaaac tataaaagaa tgtaatggtt ttaaattaga atataagtct aaattaggat
     7801 atattctaaa tattaaagac caagataaat tcgagcatta tctaagaaac ttaccctcag
     7861 atttagttga aaatccagaa caacggttgg agtctataat agtagagctt ttagtaaatg
     7921 aaggttataa aactatagaa cagttaagta aaaaatttct agtaagttca tcccaaataa
     7981 aaaatgattt aaaaaagata gatgaaaaga taaaggatac agaattaaaa ctagagcgaa
     8041 aggctcatta tggaattaaa atagaaggtt ctattaaaga aattcaaagt atattggtgg
     8101 atagttattt tagagggaat agaaatataa cagagtacag gaataagttt atagataatt
     8161 taaaattagc taatattaga agtacaataa aaaatgtact taatgaacat gatttagaag
     8221 caaatttaac agaacttgag gaaatattag cacaaattat tatattgtat ataagagtta
     8281 gtatgagagt agtgggaaat gctagcaatt taaaattata tacagaagat ttaattatag
     8341 ataaattatt agataaaatt tttagagata aaaaatataa ccttaattat gatgaaaagt
     8401 attatttaaa ggagcttata aaactaaaga ctaaagataa gaaagccact ataaagaata
     8461 ttgataagaa taaacttcaa gatattatgt tcgaattttt tagagagata gataaaaaat
     8521 ataactctaa ttttttagaa gataaagagt tttttaactt attttactta catattgcat
     8581 gtttaataga acgtataaag aagaaccaca agataataaa tcctttttca gttaaaataa
     8641 gtcaacagta tccaactgtt tttaatttat ctattcaatt ttcaaaaatc atagaaaatg
     8701 agtatcatat aaaaataagt caagatgaaa tagggtttat agctactcac attgctgttc
     8761 cttttgaaaa gagagaagaa gctaatttta ataaaaaata taaaatagca ataatatgct
     8821 cttctggtgg aggtagtgca tttttgataa atttaagact taaagaaatt tttccaaatg
     8881 ctgagataag aaatttttca ttactagaag aaaaagctgt aatagaattt gcaccagatt
     8941 tgattttttc aataacaaat cttttatttg aaataaatgc tccagttata cttataaatg
     9001 aaattttaga cgaattggat tatttagata ttaaagaaag tgttagattt gcagaccata
     9061 taggaaatat atcaagccca aaacaatata tattaggtct atttgataag aatcacttta
     9121 ggtgtataaa agataaagct aagtataagg atatccttga tagtatgtca aaatgtatag
     9181 ttgacgaggg agcttgttct ccaacctatc ccaaagatgt atgggaaaga gaaagctatt
     9241 tgagtactat ttatacaaat ggggtggcta tacctcatcc aatcgagatg acaggaaaca
     9301 aaaatataat atcagtagct ttgatacaaa ctgatattat ttatgaaaat agggtgccca
     9361 aaattatttt catgatttca ttaataaagg gaaatttaga acttcataag caaatatcta
     9421 aatatttaag taagattatg gcaaataagg atatggtaga catgctaaat aagtcacaat
     9481 cttatgaaga gtttatgtat aagttaaaaa tctatctggg aggttagaca tgaatataga
     9541 gttttttaag aggttgtcag aagcagatgg tatagcatct aatgaagaag aggttagaca
     9601 tgttttattg gaagaactaa aggcttatag tgataaaatt atctgtgatg ggctagggag
     9661 tatcatcttt tctaaaataa aagatgagag tgcaccaaac gtaatgattt gtgctcatat
     9721 ggatgaagtt ggatttatgg tgagaagtat agacaaactt ggtatgattc acttaataac
     9781 aataggagga gtaaaacctc ttgcacagtt tgtacaaaaa gttagaatta caacaaaaga
     9841 aggaaagaaa atccctgctg tcataaatgc tacatataat aatggtaagg ctgaaaatat
     9901 atatgcagat attggagcat atacagaaga agatgtatat aacctaggga ttaatgttgg
     9961 ggatatggta acatatacaa caagttttga ggaatttact ttaccagacc gattagtggg
    10021 aaaggctttt gatgatagga taggatgttt tgtgatggga gaagttttaa aagaacttag
    10081 gaaagaaaat ctaaattgta atattcactt tgcggctaca agtagtgaag aggttggaat
    10141 aaggggagca aagacatcaa cacagttaat aaatccagat atagtatttg taatagatgt
    10201 agcatgtgct aaaaatgagt ttgtgagaga ctatacaaat cagaaacaaa ttgataaagg
    10261 tgtaatgcta atgcatagag ataggactct agtccctagt agaaaaatga tagattatgt
    10321 aatggaaatt gctgataaaa ataatatacc acttcaacat gatatgtttg aatcaggtgg
    10381 gactgatgga ggagaagcac atctcgtaaa tgaagggaaa ccttgtgtag taacttgtgt
    10441 accagttaga tatggtcatt gtgcattttc aatagtaagt aataaagatt tagagaacat
    10501 tataagattg tatacacagt taattttaaa ttttgatgaa gaacaatata aacatataag
    10561 aaattttatc taaaggagaa taagaaaatg tcaacagaag tacaaataat ggagcttata
    10621 tcaactgcag gagagagtaa atcgaaagct tttgaggctt taaaaaaagt aaagtcaaaa
    10681 gattttaaag gagcaaaatt gttaatagag gaggctcgta aaatagatat tgaggctcac
    10741 agaatacaga cagaattaat aactcaagat ttaaatgaag atgttgaaag cccaacaatg
    10801 agtcttttaa tggtacatgc tcaagaccac tatatgactt ctcagctagc aaaagacttg
    10861 atagaggctt tgatatattg tctcgataag taattgtaat gtagaaatag attatttatg
    10921 taaaaattct tttaaaagtt tagatgcttt taagagataa taaaaataca aactttagga
    10981 ggaattatta tgaaaatatt attatgttgt gcaggtggat tttctactaa tatgttaatg
    11041 caaaatatga aaaaggtggt aaaagagagt gctaaactca atgaaaaaga ttttgagttt
    11101 acagctatac cagcagattc aatagaaagt gaagttgatg attgggatat agtacttata
    11161 ggtcctcaaa tagctcataa aatagacttc ttaaaaggaa tattagagcc aaaaaataag
    11221 ccttttgcag taatagataa agatgtatat ggaaaaatgg atggagctac agttatgaag
    11281 ttggcattaa taacttataa gaaacatcaa ttagctcaag gataataaaa ataatgaggg
    11341 aaaagggaga ttagatatgt tttcaaaatt tgaagcattt atgaatagag tatttatgcc
    11401 tttagctcat aaggttgaca atcaacgtca ccttggttct ataaaggctg gtatggttgc
    11461 tatgacacca ttcacaatat taggaagtat atttgcaata cttccagcac ttccaaatat
    11521 gcttggagaa aataatccaa taagcaaatt catacttaac aattcagcaa tattggattt
    11581 accagtaagt ctttccatag gtttaatagg attatatgct tgtatgtgta ttgcttttaa
    11641 tctggggaac tactataaat tatatatacc aggttgtgtt gcactatcaa ctttttcttt
    11701 tttattccta gtagcctcat ttacaccaga tggagcttta gaaataggaa atttaggagc
    11761 taaagggcta tttacaggta tgatagcagg gcttggttct gtggagttat ataatttttg
    11821 taataagaag aatatcacaa taaaaatgcc agaaaatgta cctgattttg tatctaggtc
    11881 ttttgaatta atacctacta ctataatagt ttgtggaact tttatagttg ctcgttttat
    11941 ttcattaaaa gtatttggag aattacctcc acagatactt actcaatttt tatctccatt
    12001 agtaggaagt atggataacc catggtcagt tcttgcactt aactttgcta tatgtactat
    12061 attctttttt ggaatacatt catcagtatt tagtcctata actagaccta taatgattac
    12121 atttatagct gaaaacatag cagctatgca agctggagaa acaatacctc atttctttac
    12181 agcaggagct tcaagtgcat tctttggatt tacaggatgt ggaattagta taggttgtgt
    12241 aattgcatgt atgttatcaa aaaatgcttc ctataagaag attggacgtg tatcattatt
    12301 ccctgcatta tttgggataa atgaaccaat attatttgga gcaccgataa tattaaatcc
    12361 aataatgttt ataccacatg tatttggtgg agctataata ggtacactac caatgttttt
    12421 tatgcactgg ggatggttag caaagccagt atttgaccct ccatatgtag gggtattctt
    12481 agaaggattt ttaactaatg gagattggca ttctatatta gcaaatgcat tgcaattagt
    12541 attagcagtt ttattatatt ggccattctt taaaataatg gaacgtcaac aaaataataa
    12601 aaaacaaaaa gaagaaacta agaatatatt ctctaaagaa gaagaagact tattggatga
    12661 tttaggattg gatttctaat attttgttat gaataataca atagagagat tagtatcctt
    12721 aatctataaa agaggtgttg acgctctttt gattaaagca aaaaatacta aaagatatat
    12781 aggagcttta tcaggtagtg gtgtatatgt gcttgttact aaggataaaa attatcaaat
    12841 tctagatggc agatatattg atgaagcaga taaaaaaacg actggtttca taaaaaggat
    12901 tgtatctcaa ggttcttata taccaactat aattgagtta ttaaaagaat taaatataaa
    12961 aaagttagca atagaaaacc aagctatgag tatacaagag tatctttcac taaaaaatga
    13021 aggttttgaa atcaatttaa taacaaatga attatggaag ctaagggcta taaaatctaa
    13081 agaagaaatt gaacttatta aaaaggcttg tgagattaca gatgaagtat ttgatgaggt
    13141 tatttctgaa attaaaaaag atatgactga gctagaagta tcagctctaa ttcagtatca
    13201 tgcattaaaa aaaggtgcaa gtggaatgtc ttttgaaaca atagtggtat caggagaaag
    13261 aggtgcaatg ccacatggaa gacctacaaa caaaaaattg aaagtgaatg aagctataac
    13321 aatagatttt ggtgttgttt atcaagggta tcaatcagac atgactcgta caatatctat
    13381 aggtaaacct cctaaaatta ttaaagagat atatgatgta gtattggaag cacaattatc
    13441 tgcaatagag tcaataaagg aaggaactag ggcaagtgat gttgacaaag tggctagaaa
    13501 aattatagat aaacatggat ttggcgaata ttttaatcat ggactgggtc atggtatagg
    13561 tcttggagat ggtgaagttc ccactttaaa tccaaatagt gaagatatat tagtggaagg
    13621 aatggtaatg tcttgtgagc caggtattta tattccaaat gtagggggag ttagaataga
    13681 agatgatatt gttataatag atggaaaagg tgttccactc aataagacat ccaaagagtt
    13741 tataatatta ggagagtaaa attatgaaat ataattttaa taaagtatta aatcgtaaag
    13801 aaggaaattg tagaaaatgg agcaaccatg tgattaaaga aaaattcggc ttaaatgaag
    13861 atgcaattcc tatggattta gctgatatcg attttgagtg tgctcctgct ataaaagaat
    13921 ctatcttaaa aagagcatca gtaggagatt atagttatac ttttatagga gatgacttct
    13981 atgatgctat tataaattgg aataaaagaa gatttgatgt atatatagaa aaggattgga
    14041 taaaattaac ttttggtact gtttcaaccc ttcattatat agttcaagca tatactaaag
    14101 aaggagaggg tgtattgata aatacacctg cttatgaccc ttttgcagag gctgtagcaa
    14161 ataataatag aaagttgtgt tgtagctcat taaaattaga taacaataga tattatttag
    14221 atttagagga tatggaaaat caaatgaaat acgagaatat aagattactt atattctgta
    14281 gtccacaaaa tccatcaggt cgtatatgga caaaagaaga actatatcaa gtgtcagagt
    14341 tatgtttaaa gtataatgta attttggtaa gtgatgaaat tcatagagat ataatattta
    14401 aagattatag atttgtatct ttgtggaatg ctcatccaga aatttataaa aatagtataa
    14461 tctgcgtatc tcctaataaa ggcttcaact taggtggatt aaaaacatca tatgtattaa
    14521 taagagatgt aaaaattagg gagactttat tagaaaggct aaaaagtaat tcaataactt
    14581 ctccaaatgt atttgcaata ccagcaatag ttgcagcata caatgaaagc gaagaatggc
    14641 tagatgctat gactagttat gtagaggaga attttgaaat agtttatgat ttctttgaaa
    14701 ctaatatacc aaaagccaaa gtgatgaagt cagactcttc ttttttagcc tggatagatg
    14761 taagagaagt atttagaaat gaagaagaat ctaaagaatt ttttagacat gcaaacttaa
    14821 ctatggtagt tggaagttat tttgtgaaag atggagatgg atttattcgt attaatgtgg
    14881 ggtgtcctag agaaacatta aatgaggctc taaatagaat caaaaaaacg tatataagta
    14941 tgtattgtta aatcataaaa aaagtatcta tggtttatat aaaaacacat tatttagtta
    15001 tcaaatatta ctggaatttt gtattccagt aatatttttt gattaaggaa tattattgag
    15061 gaatattaaa taatattatt tcataccctt atattaactt atataaaaat attttattat
    15121 tttgggaacg ggttagctaa cctttatcta gtgtatattt atattgtaag aagcagtaaa
    15181 aacttttccc ttactaagtt tattaataaa cttcttatct ttataaattt tgttagaatt
    15241 tatactatca gcaagaccat accaaggttc tatacataaa aaaggagcag tagaattagt
    15301 ttcactataa taaggagtcc aaataccaac tagagggaaa tcttccatag atatagttac
    15361 atatttacta ccatcattat tatatataga cacttcatct atgttggtgt atatcaaagc
    15421 atcattcttg aatacttctg gatttaaatg taagtttttt aattttccaa taggtattat
    15481 atcatctgta aaagaaccat ttaaattgat tttttctaca tcatttttac ttttaaactc
    15541 aaggtagtgt ttagaaaaat cattttgttt gtaaaaagga aggttgaatg caggatgtcc
    15601 acctatagaa aagaatatat ctttagagtc agtatttttt acaatccatt ctacctcaat
    15661 actattatca tttaatgtat agtttatgat tagctcaaaa gaatatggat acttctttaa
    15721 agtggattca ttatctgtta atttataaga tacaaatgta tctcctttat ctacaatctc
    15781 aaagtccata tctctagcaa acccatgttg agtcatgcta tataaatttt cttctattat
    15841 tgtttcatta tcaaaaagtt tacctactat agggaacaat ataggtgatt gtctacccca
    15901 atatttttta ttaccatccc aaagaatgtt tttgtcgtat tttttagaaa atattttagt
    15961 tagttcagca ccaaaactgc ttgattcgat aattaaattt tcattttgta atatattcat
    16021 ttaaaatctc ctttattata ttttatgagt atattatact ataaagtata aagattatta
    16081 aattttattt gatattatat ttgaaaggta gattttagta tattttgaaa attttgtttt
    16141 gaaaatttgg gattatttaa gaaattttgt attataaata gaaggaaata gataaattgt
    16201 atagaataaa atatattaag ataagttaat aatgttaaat gggaagtgag tttatggaaa
    16261 aaccaaatac aaaagttgtt aactttcaag agtataaaga cagaaaaaac caaagagaag
    16321 taaatagaga cgaactttta aagcttataa aaaaaattgt gacttcaaaa tagggagttg
    16381 ttaaactccc tattttaatg ggtttcataa taattaagac attctgagtc catctatata
    16441 atctttgaat tgtgagaaat ctgattcact acttaattct atggtttctg aaccttccgt
    16501 ataaaaattc ttaagataga tagtataatt attatcaaca caatcatgat aaatacatct
    16561 atatccatct tcatacaaac tttttaactt agaaaaatca tccacaatat catctcctta
    16621 aagttctttt aaatatattt ttacaaaaag catctaattg tatgcaaatt gacaatgtaa
    16681 aataaaggaa atgaacataa aatgtagaat aatttttata tgtatgtaaa aataaaaaga
    16741 aaaagttgaa atttttagaa aataagagta ttttttatct aaaaagagag tttaaaaaat
    16801 aaaaaaatgt tgggaggata aaaaatgagt ttattagaaa gtatatcaaa aaacatatat
    16861 tccctagata actcttctat tgaaaaaaca aagcagagat tggataggct tatacatcca
    16921 actggaagct taggaaagat agaagatatt tgcatgcaat tggcaggaat atttggcaat
    16981 gaaaattttg acacaagtaa aaaggttata attgcttttg cgggagacca tggtgtatat
    17041 gaagaaggcg tagcacctga ccctcaaaat ataacaaaat tacagtttcc aaatttttcg
    17101 aaaggtctat gtggagttgg agtaataagt aaatttgtag gggcagatgt tgtagctgta
    17161 gatgtaggaa taaactgtga tgaaaaactg gatggggtat tagactacaa gataagaaaa
    17221 gggacatcaa atatggcaaa aggtccagct atgagtaaac aagaagccat tagatgttta
    17281 gagataggta ttgaaatagc agagcagtgt atagaaaaag attataaggt tattggtatt
    17341 ggggagatgg gtatagcaaa tactactcca agtacagcaa taatatctgt aatttcaggg
    17401 tgtgacccgt tagaagttac tggtataggt gcaggtctta agaaagaaag actaaagcat
    17461 aaggctgaag taattagaaa ggctattgaa attaataatc caaatccaac tgatggagta
    17521 gatattttat ctaaagtagg aggatttgaa ataggctcaa tggcaggtgt tatattaggt
    17581 tgtagtgcta ataggattcc agtagtaatt gatgggttta tttcttatgc agcagcatta
    17641 attgcatata agataaatcc aaaaactaga gaatatatga tagcatctca tttatcagca
    17701 gaatcaggaa ctaaaagagc attagacata ttaaaattag accctctatt aaatatggat
    17761 atgagattag gtgagggaag tggagctgct ttagcatttg atataataga agcttcaaac
    17821 tatacttaca aaaatatggc aacttttgat gaaattgaca tgggaagata aatataaaaa
    17881 tttaatatgt aggagtgttt tgatgagtaa aattattcta gtaacaggag gagctaggtc
    17941 agggaagagt aactttgcag aaaaactatg ttttgacaga aataataata cagcttatat
    18001 agcaacctct attccatttg atgatgaaat gaaagataga gtaaaaaaac atcaagagaa
    18061 tagacctaga aactggaata cttatgaaat atatgaagat atatattcca taattaagga
    18121 gatatataaa gaacatgaaa ctgttatact agattgtgta acattattag taaataatct
    18181 aatgtttgaa cacaatctaa atatagaaga gtctagtcaa gaagaaataa acaaattaga
    18241 acaatacata aaagaacaag ttgtcaaact tattgaagaa atagaaaaaa caaatctata
    18301 ctttgtattt gtaacgaatg agttaggtat gggaattgtt cctgggaata aacttagtag
    18361 aatttatgct gatattgtag gtcgtataaa tcaatatata gcttcgaaaa gtaatgaagt
    18421 ttattttgta gttagtggca tagctatgaa gataaaggag tagtatgcaa ttatgaaaag
    18481 atttatttta atactacagt ttttgacaag gatacctata aaattaaatg taggatttga
    18541 tgatgaattt tataagtcaa tagtatattt tccacttgta ggttttgtca taggtatatt
    18601 atcctattta ataggatgga tttctatgct tttatttgaa ccatttatag cttctataat
    18661 aataactcta gctggtgtct taattactgg aggacttcat atagatggat taggagatac
    18721 atttgatgca atatatagtt atagggataa agaaaaaatg cttgaaataa tgaaagattc
    18781 aagattaggt acaaattcac ttctagcaat tatgtttgta cttttattaa aggttggatt
    18841 cgtttacgat ataataagta ataattcatt gtggattata atttttatgc caatgattgc
    18901 aaggttagga gtaatgttat tgacatataa aaccgtgaca ccaagagaaa aaggaatggg
    18961 aaatttattt ataggaaaat taactacaag tatgttaata actgctataa tatacacatt
    19021 attgatagtt gctcttatta ctaaatttat atttttatta cctaatatag tgttgattaa
    19081 agtattaggt tcgattatag tggtttttgt atttataata ttattcaaaa aacatattta
    19141 taaaaaaatt gacggagtaa caggagatat attaggctgt ggaatagaac tttcagagct
    19201 tgtatattta atttacatat atttgttaat ttttatgttt ttttaaagta aaaagtggtg
    19261 ataatatgat aagattaata ttaataagac atgcactgac aaatgataat aaaaaaggaa
    19321 gattatcagg ccatataaat agttgtatta gtgaagaggg caaactacaa ataaataaaa
    19381 ttaccagata tctgagtaat gaaaacatag ataaggttta tacaacacca tctacacgta
    19441 ctaaagatac agtagaaaaa atatcaaaat tgaaattatt agaaatagaa gaaaaagaag
    19501 ctttaagaga aattagtttt ggagactttg aaggaagaac ttttgaagaa attaaaatca
    19561 aatatccaaa tgagtttgaa aaaatgataa aagaaggtaa caactataga tatccaaatg
    19621 gagaaagttt gatagactct tataaaagag tggcaaaaga aattgataat ataattttag
    19681 aaaatgatag taatttagat acaaagacaa tacttatatg ttctcatgca ggaacaataa
    19741 gaaatataat aacacatttg atttctggta gttataagta tcactggaac tttaaaattg
    19801 ataatgcatc tattacagtt ttagaaattg atggtggatt tgctgtaata gataaaatga
    19861 attttacaga cttcatataa tttaatcaaa accaaacatt acaatctgtg tttgtaatat
    19921 atctgtaaaa ttagcaatga aaatagaata ttagattaaa attaggttct taattagatg
    19981 ttaaaaggga aaaaggttag atgcctttgc agcccccgct actgtgaaac caacgaaact
    20041 ataaatacca ctgtcagttt gatgggaagg ttatagaagt aggatgaagt taagccagga
    20101 tacctgccta atttaattta aaacaagagg tcttcggggt gaaagatttt taattaatat
    20161 atataaaagt cctatcttta gaagtattag gacttttttt aatttgtttt ttagtaaatt
    20221 ttaacaagga gggatggaaa gtggggaaaa aaataatgct acaaggaaca gcttcaaatg
    20281 taggtaaaag tgtcttagta gcaggtttgt gtagaatatt taagcaagat ggttatactg
    20341 ttgctccttt taagtcacaa aatatggctt taaattcttt tataactaaa gaaggattag
    20401 aaatgggaag agcacaagta tttcaagcag aggctgcgaa aatagagcca atagctgata
    20461 tgaatccagt tttattaaaa ccttctggga ataataaaag tcaagttatt gtaagaggta
    20521 aagttgtagg agaaatgcct tcttctaagt atcatgatta taaattggag ttagtaggtg
    20581 tgttgaagga aacatttaat agcttaaatt caaggtatga tattgtagtt atggaagggg
    20641 caggaagtaa tgcagagata aacttaaaag atagagatat ctctaatatg ggtatggcag
    20701 aaatagctga tgcacctgta ataatagtcg gagatattga tagaggaggc gtatttgcct
    20761 cattagcagg aacaatgctt ttattaaatg aagatgagaa aagaagagta aaaggtgtaa
    20821 taatcaataa attcagagga aaaaaagagc ttttacaaga tggtgtaaag atgctagaag
    20881 acatcataaa agtacctgtt ataggagtag taccttatac agatataaaa atagaagatg
    20941 aagacagtgt aactacgaga tttaagaaaa aaatgaataa aagtgatata cacatagaaa
    21001 taattagaac cccacatatg tcaaatttta cagattttaa tatatttgag acacaagaag
    21061 atgtaagtat tagatatgta gactatggag aatctttagg aaatccagat atattaataa
    21121 tacctggaac taaaagtact atagacgatt taacatatat aagaaaaagt ggtcttgaat
    21181 cgcaaatcaa aaatttacat agtcaaggta aattgatatt tgggatatgt ggtggatacc
    21241 aaatgttagg taaaaaatta aaagaccctt atcatgttga aagtgaaatt gaagaagttg
    21301 atggaatagg tcttttagat acagaaacaa cgtttgagaa agaaaagact acaacacaag
    21361 tagaggctac tattgttgaa tgtatcagtg aatacatgaa taaccttaag ggaaaaaaag
    21421 taaaaggtta tgaaattcat atgggcatta caaagcgagg taatgatgta agaagtttag
    21481 atttaataac taaaaaactt gataaagaag tgaattatac tgaaggaagt gtaaataaag
    21541 aggggaatgt aattgggact tatcttcatg gaatatttga tgaaataagc tttacaagag
    21601 caattttaaa caatataaga aagaaaaaag gtttaggaga attagaaagc aaagtaaact
    21661 cttttaatga atttaaggat aaagagtatg ataagttggc tgatttttta agagaacatt
    21721 tagatataga gaaaatatat gagattatga aataatgatg acctttattt ataatttagg
    21781 taggaggtgt attatgaaaa aaattttaat tgctggtact aatagtggag taggtaaaac
    21841 aacaatatca ttaggaataa tgcaagcttt ggttaagaga aatatgaaag tacagccata
    21901 taaagtaggg ccagactata tagacccttc atatcacact tttataactg gaagacattc
    21961 tagaaattta gattcttata tgttagatga tgaaaaaata aagtatatag taaataagtc
    22021 ctcaaaagat gcagatattt cagtaataga aggtgttatg ggcttatatg atggttttgg
    22081 aatagattta gataattgta caagttcaca tacttcaaag gtattaaagt cacctgttat
    22141 attagttata aatggtaaat ctatggcagc atctagtgct gctatggtac ttggatataa
    22201 ggaattagat aaagatgtaa atataaaggg tgttatagta aataatgtaa agactaatag
    22261 ccattatcaa ataattaaga gttctataga aaaatattgt aatgttgaag tattggggta
    22321 ttttcctcca aataacaaat tctctttaga atctcgacat ctaggattag ttcctagtgt
    22381 agaaatgaaa tcactaaggg aaaaatttta taccttagca gatgaaattg aacactatat
    22441 agatattgac agaataattg aaatatcaga aagcgatgaa tttgagagtg attttgattt
    22501 tcaaactttg atagaaaata ataaaataaa agaacatgtt aataataaat caatagctat
    22561 agcatatgat aaagcattca atttttatta tagagaaaat atagagcttt tagaggaact
    22621 tggtttagaa ataaactatt ttagccctct tgaagatgca tcagtgccaa atgcagatta
    22681 tatttatatt ggaggaggtt ttccagaaat atttggaaaa gaattagaag caaatgagtc
    22741 aatgagaact tccatattag aagcacataa caataatata cctatttatg cagaatgtgg
    22801 aggactgatg tacctaggtg agaaactatt gaatcaagaa gaacaagaat ttaatatggt
    22861 tggaatattt agtggaatta gtaagatgac atcttcttta aagagatttg ggtactgtat
    22921 tggtgtagcc aaggaaaata ctcttttatc taaaaaaggg gaatctatta aagggcatga
    22981 gtttcatcat tcaatatttg aaagtgatga aaaatgtgta tattcaatga gaaaagaaag
    23041 agatggaaat atagtagaag agtgggatgg tggttatagt aaaggaaaca ctttggctac
    23101 atatcttcat actcattttt ataataactt aaattgtata gaaaattttt tgaaaaaagg
    23161 aaatgaataa atgagtattt tatctattta tataggatat gtgacagact taattgtagg
    23221 agacccatat tcttttcctc atccagtgag atttattggt aaacttataa attttactca
    23281 aggtataata agaaaggtct ctaaaaatga taggcagtta aaatttgggg gatttatatt
    23341 atggtttata accgttggaa taacatattt aacaacttat gctatagtga agctatttag
    23401 ttttaatata ttattgagta ttgtagtgaa tagttttata atttatacaa cactagccac
    23461 aaaatgttta aaagacgaag cattaaaaat ttataatgta ttaaaaaccg aagatataga
    23521 aaaatctagg attcagctat cttatatagt aggtagggat actactaatt taagtgaacc
    23581 tgaaataata agagcaactg tagaaactgt tgcagaaaat actgtagatg gtataattgc
    23641 gcctatgttt tatgcattta ttggaggagc accacttgct atggcctata aagctataaa
    23701 tacattagac tcaacagttg gatataaaaa taaaaagtat aaagatattg gttttgcatc
    23761 tgctaagatt gatgatatag ccaattatat accagctaga atatctgtta ttcttatgac
    23821 aattggaagt ttctttttaa attataacta taggaactgt tttaaaatct ctattagaga
    23881 tagaaagaat cataaaagtc caaattgtgc tttttcagaa ggcgcagtat ctggtgctct
    23941 aggaatacaa ctaggaggta ccaacgttta ttttggggaa aaagtatata agccaacaat
    24001 aggggataag cttagggaga tagataaaga agatataatt aaaactaata aaattatgta
    24061 tgtatcttca tttgtatcta tgttggtatt tacactaata catgtgttat gtaggatgat
    24121 tttaattaac ttaattatat aaattattgt ttgctaactt aagggggaca tagatgaagg
    24181 atttagggca tggtgccaat gtaggtgaaa tggcaagatt atatgggaaa aacccaaaag
    24241 aaataattga ttttagttca aacataaatc caaatgtatt accaaattta gagagataca
    24301 ttttaaaagg attagaagag tgtaggaatt atccagatat aaattataca aacttgagag
    24361 aaaatatatc aaaatatata ggtataaatc cagactttat aatacctgga aatggtgcaa
    24421 cagaagtgat ttatttgctt atgaagagtg ttaaaaaaaa attggctata ataaatccga
    24481 ctttttcaga gtatagaaga agtgctgagt taaataattt agatattata gatttagagc
    24541 tagatttaga aaataacttt aaacttaata tagatataat aaaagaaaat ataaaaagat
    24601 ttgatagttt atttatatgt aatcctaata atcctagtgg taatgtccaa gatttaaagg
    24661 aacttgttca tttactaggt aaacataata aggtactaat aattgatgaa actttcatgg
    24721 aatttgttga agatgaaagt aaatacagtt tggttaaata tatagaatca aataaaaata
    24781 tatttataat taaagctgtg actaagtttt ttggtatgcc tggtttaagg ctaggatatg
    24841 gtcttacaag caacactgaa attatgaaca aaatttatga acacaaagag ccatggacta
    24901 ttaattcttt tgcagatata ctatccaatt ttatttttga agataaagag tatattaaaa
    24961 atagtaaaga atattacata gaagaaagaa aatatatgtt acaagagttg agaaacataa
    25021 gaaatataaa ggtctatgat acagatgcta attttatttt gataagagca tataaaaaaa
    25081 caactaaaga attgaaaaaa gatttgctta agcaaggaaa catattagtt agagatgcgt
    25141 ctaattttat aggattagat gatagtttta taagagtggc tataaaatct catgaagata
    25201 acaaaattct tatagaaaat atgaaaaatt tattgggtga ttaaaatgaa atcttatgga
    25261 atatgcccag catcttgtgg agaatttgta caaggtataa ttgatgatga agaatattta
    25321 tgttcatatg caatagatat gtattctgaa gtgtatattg aagaaaaatt agtagatata
    25381 aatttaggga gatataagtc aaggttagca attgaaaagg tatttgaaaa atttaattta
    25441 cctaaaaaat atactaaaaa tatttcttta aatataaata gtaaaatacc tgttggaaaa
    25501 ggaatggcaa gttcaactgc tgatatagga gctacaataa aggcaacatt atcattgata
    25561 gataaagatt taagtagtga ggagatttct aaattagcag cagaaataga accaacagat
    25621 tctatattta tagataaaaa tagtatattt aatcctctaa atggaactgt tataaaatac
    25681 ctaggaaatc tgaccaatgc gaaagttata atacttgaac caaacaaagt actagatact
    25741 atgaaaatta gattgaggca agattataat aaattaaaag tagaaaataa agaagtaata
    25801 aaaaaatcat ttgctctttt agaagaagga ttgaaaaaaa ataatttatc tctagttgga
    25861 gaggcttgta ctttgagtag cttagcaaat gagaatatag aaaaaaaaga gtatttaaat
    25921 gaaataataa aaatatcaaa aaaatatgga gcatatggag taaatattgc tcacagtgga
    25981 actgtagtag gtattttaat tgataagtct atgaatgata aaaagatgat agatacctta
    26041 tgtgaatcta acataaattc tgtctataat aaaatttata cacaaaacat aattaatgga
    26101 ggaattaagg gggaaataga atggaataca taaagaatcc tatgaaaata gaagaaaaaa
    26161 gttttgaatt gatacaagaa ataatagacg aaattagacc agattataaa tttaagaata
    26221 atattgaaga aaaaataata aaaagagcta tacatactac tgctgatttt gattacttag
    26281 atatattaaa aatatcagaa gaagcagttg atagtataat agatgcatta aaaaataatg
    26341 caagtattta tactgataca aatatggctc ttagtggtat aaataaaaga aagttagaat
    26401 cattaggatg taagtataaa tgtttagtgg cagatgatga aactgtaaaa ttagctaaag
    26461 aaaaaggaat tactcgttct atggcagcag tagaaattgc agctaaagaa gaaggaagaa
    26521 aaatattcgt tttaggtaat gctccaacag ctttatataa agttatggag atgaaatcag
    26581 aaggtagatt agatttagat gcagttatag gagttcctgt aggttttgta ggagcacaag
    26641 aatcaaaaga tgaagttgaa aaaacagata taccatatat aatttctaaa ggtagaaaag
    26701 gtggcagtaa tttagcagca gcaatagtaa atgctatatt atatactatg taggtaccta
    26761 tatggaagaa tatgtatata tagatggaaa aaaatataga agaggatata ctacaggttc
    26821 atgtgcaaca ggtgcatcta aggctgctgt atatatgttg attacaaaaa atagaatcaa
    26881 tactataaat atagatactc ctaaggggat accattacta ctaaaagttg ataatataaa
    26941 tatttctgat acatttgtgg aatgttccat aaaaaaagat ggtggagatg atatagatgc
    27001 aactcatacc atggatattt atgcaagagc tgaaattgta gctaaaaatg ataagaacaa
    27061 agggtatctt actctaaagg atatagatag tttaagcacc aatagtgagt gtaaaagtga
    27121 gctctataag tttattaggg tttatggcgg aactggtatt ggtgtggtta cgaaaaaagg
    27181 gcttagtgtg gatgttggta aacctgctat aaatccgact ccacttaaaa tgataaacca
    27241 tgaaataaga aagcttatag gagataattt tgaatctata cttggaaatg ataaagtttt
    27301 aaaaataaca atctttgctc cacaaggaga aactgtagca aaaaaaacat ttaatccaag
    27361 attaggtata gttggaggaa tatctataat aggtacaact gggattgttg aacctatgag
    27421 tgatgagggt tggaagaagt ctctttctat agaacttcag atgaaaaaag aacaaggctt
    27481 agataaaata atattggttc caggaaatca tggagaacag tttataagag aaaaattaaa
    27541 cttagatatt aagtatgtag ttagggtaag taattttata ggctatatga ttaaagaagc
    27601 tcaaagaata ggatataaaa aaatcttaat ggcaggtcat ataggtaaat ttataaaagt
    27661 atctgctggt atttttaata ctcatagtaa ggtagcagat gctagaagtg agatattagt
    27721 ggcaaactta gctttaatgg gagctagata cgaattttta aataaaataa atcaatgcgt
    27781 aactactgaa gaagctgtag agctaataaa taatagtgaa tatagagaag tatataatat
    27841 attaagtaat aaatgtaagg agagagtaaa gcaatacttg aatgaagatt cagatgatat
    27901 tgatgtggaa gtaatcatat tttcaatgga taagtcttta ttaggtaaat cggataatac
    27961 agatgattta gtggaggtct ttatatgata aacataatag gtctaggacc tggtaactta
    28021 gactatataa caaaaaaagg tgaaaattta atttccactt ctgatgtatt aattggtggt
    28081 aaaagaaatc tagagtctat aaaaaatttt gaaggagaaa aaatagttct ggattctaat
    28141 ttaagagaaa ttatagagta cataaataac aataaagaaa agcaaatatc aataatagca
    28201 tctggggacc cattaatata tgggataggt agatatctat ctaaaaatat tgataataag
    28261 atgttaaacg tggtttctgg gattagttca ttacagtaca tattttcaaa aatatatgta
    28321 gatatgaatg atgtatatat tacaagtagt catggcaaaa taccagattt tgattacata
    28381 ttatcacata aaaaagtatg tatggttaca gattcaaaga taggaccaaa acaaataagt
    28441 agagaaataa tagatagaaa tctaaataaa attattgttg taggagaaaa tctgtcatat
    28501 gacaatgaaa aaataacaat agcgaaacca gaagagataa taagaatgga caattttgat
    28561 atgaatgttg tggtgatttt agatgaggaa tagtgaattt ataacaggta aagttccaat
    28621 tactaaggaa gaggttagag caatatcaat aagtaagtta aatttagtaa atgctaaaaa
    28681 cctcatagac ataggggctg gtacaggaag tgtaagtgtt gaagctgcat ataattatcc
    28741 taatttaaag gttatatcta tagagaaaaa tgatgacgct atagagctta tagagaaaaa
    28801 tataaaaaaa ttcaacttaa aaaatataga agtgataaaa ggatatgctc caattaatct
    28861 agggttaaat gttaaagttg agtctatttt tcttggggga acaggaaata atctggaaga
    28921 aataatagaa tggtctaaaa aaaatctcgt tacaggagga agacttgtag ctaattttat
    28981 aataatagat acatttaatc aaactttaaa actgcttaaa aagcatggat ttaaagaaat
    29041 agatgtatgt gttttgaatg tttctaaact agagaaacta ggaaaaggtg aatattttaa
    29101 accactaaat cctatatata taatatcttg tgaaaaaggg gaaaatgatg atgaataaag
    29161 tacattttgt aggagcagga cctggagata aagagctgat aacattaaaa ggatacaaat
    29221 tattaagtaa tgcagatgta gtgatatatg caggttcact tgttaatcct gaacttttgg
    29281 aatactgtaa agaagattgc caaatacata atagtgcaca tatggattta caagagataa
    29341 tagatgttat gagagaaggt atagaaaata ataaatctgt tgtaagactg caaacaggtg
    29401 atttttctat atatggttca attagagaac aagtggaaga tttaaataaa ttgaatatag
    29461 attatgactg tactcctgga gtaagttctt ttttaggggc agcatcatct ttaggggttg
    29521 aatatacagt tccagaaatt tctcaaagtg taattataac aagaatggaa ggcagaactc
    29581 cggttccaga gaaagaatca atacaatcat atgctaagca tcagacatct atggtaatat
    29641 ttttatctgt tcaagaaatt gagaaagttg tgtctaaatt actggaaggt ggatatccaa
    29701 aagatactcc tatagcagtt atatacaaag caacttgggc agatgaaaaa atagttaaag
    29761 gaactttaag tgatatagct gtaaaagtta aagaaaacaa cataaataag actgctttaa
    29821 taatggttgg gagattttta ggagaagagt ataataattc aaagttatat gataaggatt
    29881 tcaaacatga atatagaggg taatattgct ataatctgta ttacagaaaa tggaaaaaat
    29941 ttagctgtaa agataaattc tctagtaaat aactgtgtta tatatcaagt aaaaaataaa
    30001 aaaagtaatt tagttgttga agaaacatgt gtacatacag ttcaaaagaa gttaagtgat
    30061 tttgtaggag aaatatttag caaatttgat tacataatat ttataatggc tacaggtata
    30121 gttgtacgaa gtatagcacc atacataata agtaagttta gtgaccctgc aattttggta
    30181 atggatgaaa aaggcaaaaa cgtaataagt ttattgagtg gtcatattgg aggggcaaac
    30241 agcttgacac agtacataag tagtcttatt gatgctaatc cagtaataac aacagctact
    30301 gatataaatc aaaaagcttc cttagatatg atagcaaaaa aactaaatgc acatattgat
    30361 aattttagag aaagtgtaaa agaagtaaat tctatgctag tgaataataa atgtgttgga
    30421 ttatatgttg atgaaggata tcaagttgat actaggggat ttaaacttat agaaagtaag
    30481 gatgagttaa gagatagctt ttcaaacaca tatatagaaa aattagttgt agtaagcaat
    30541 aaaataaatt gtattgaaga tattgagaat ttaaacttag ataataaatt tgaacattgc
    30601 tatagtacta aaaaaataat aaaggtaatt ccaagagata tagtgatagg aattggctgt
    30661 agaagaaaca cagatagtga gctgatgtat aattcacttg aagagtttct taataaacaa
    30721 aatatagata ttagagcaat aaacacagtt ggaagtatag aactgaaaaa agacgaaaaa
    30781 gcaataattg aattatcaaa aatactaaaa gtgccattta aaacattttc aatagatgaa
    30841 atatctaagg ttgataatct ttttgataaa tctgattttg ttaaaaaaaa tgtgggcgtg
    30901 tattcagtag cagaacctat agcatatctt ttgagcaaag gtaatttgtt agttgaaaaa
    30961 cataaatata aaggaataac tttttcagtg gggagaataa aaatatgata tacgttgtag
    31021 gaattggacc aggaagtaaa gatacaatga ctttagaagc aataaaagca atagaagatt
    31081 ctgaggctat tgttggatat aagacttata taaaactaat agaagaattt atacaaggta
    31141 aagaaataat ccaaaatggt atgaggcaag aagttgatag atgtaaacaa gcagtagagg
    31201 aagcgaaaaa aggaaaaaaa gtagcagttg taagcagtgg tgatgctgga atatatggga
    31261 tggcaggtct cattttagaa ttaatatcta aagaagatga agatataaaa gtaaaggtaa
    31321 ttccaggtgt tactgcaagt attggtgcag cagctatact tggagctcct attatgcatg
    31381 atttctgtca tataagtttg agtgatttaa tgactccgtg ggaagtaatt gaaaaaagat
    31441 tgagattggc tgctgaagcc gattttgtaa tttgtttgta taatccaaga agtaagggaa
    31501 gaagtgaaca tctaagcaaa gcatttaaaa taatgggtga gtttaaaggt ggagatacac
    31561 ctgttggagt ggtaaaagat gtaggtagag aaaaagaaga aaagtttgta tgtacttttg
    31621 aaaatatgga ctttgaaaaa gtcgatatga ctacaatggt tataatagga aataagtcta
    31681 cctatattaa tggtgaattg atgataactc caagaggtta tacagtatga ttttaatttt
    31741 aggaggaact tcagatagtt tatctatatg tgataagata aatgaactga aaaatcaacc
    31801 atatatcctt tcagttacta cagattatgg aagggaactt gcacaacaac atgcagagaa
    31861 tgtaatttta ggtaagcttg gaaaagaaga tatgctaaaa tttataaaag ataataatat
    31921 agtaaaaata atagatgcca ctcatcctta tgcagttgaa gtatccaaaa ctgctattac
    31981 ttgtgcaaaa ttattgaata tagattatat aaggtttgag agaaaatctt taattgaaga
    32041 aatagattat gataataaat ttatagtaga tacaattgaa gaagcctgtg aaatagcaaa
    32101 taaaataggg acaaatatat tcataggaac aggaagtaaa aatttgaaca gatttataga
    32161 ggaaataagt gataaaaatt tagttgttag agttcttcca acgagtgaag tcatattaag
    32221 ttgtgaaaaa ttaggtttaa gtgcagataa tatagtagct atgaaaggtc catttagcca
    32281 gtatataaat gaagaaacat ataaacatta caatatagat ttagtcataa caaaagaaag
    32341 tggaatagct ggtgggttct tagagaaggt aaatgcatgt aaaactttca atataccagt
    32401 aataattata aaaagagaat cgattaacta cgaaaatgta tttaatgaca taaataaaat
    32461 taaagacata cttgtgtaat ttttaggagg agaatatatg aagaaagcct tattagtagt
    32521 gagttttggt acaagctatc atgaaacgag agaaaagaca atagatatat gtgaagataa
    32581 aataaaaaat tcgttaaaaa gccatgattt ttttagagct tatacatcaa atatgataat
    32641 aaataaaata aaaaaaaggg atggaataga aatagataat ccaatacagg ctttagataa
    32701 aatatatgaa caaggatatg atgaagtaat aatccaaaca cttcatatta tatgtggcga
    32761 agaatttaac aaattaaaag aacaagtaga tggatattct tctaaattca aaaagattgt
    32821 attaggaaga cctttgctta cacatattga agattatcag gaagctgtag aggcaattaa
    32881 gcatcaaatt cctcatatgg aaagtaatga agcagtagta tttatgggac atggaacact
    32941 tcatgaatca cattcagcgt atccagcatt ggaatacatg cttagggata atggaataaa
    33001 tgcttatgtt ggtacagttg aagggtatcc agaaatagaa catgtaataa gaagattaaa
    33061 agaaggaaat ataaaaactg taaatttgat gccatttatg ttagttgcag gagaccatgc
    33121 tataaatgat atggcaggag atgaagaaga ttcttggaaa acaatattag aagaagatgg
    33181 atttgacgta agagttcatt taaaaggact aggagaaaat tcttatatac aagataaatt
    33241 tgttcgtcat gctgtaaaat gtgcagagaa tgctaagttc tatggtatag gagcagggcc
    33301 aggagatggt tctttactta cgataaaagc ggttaatact ttaaagaaac tggatattct
    33361 atacactcca gaatcaaaaa agggtggaga tagtctagct ttatcaatag ttagtgaata
    33421 tttacctgaa tcagtggaaa taaagtctag gcatttccca atgagttttg atgggaatga
    33481 aaaaagttta gcttgggaca atgtagcaca agaaattata tcagatgtta atgatggtaa
    33541 aaatgtagga tttgttacat taggagaccc tatgatttat agtacatatg tatatataat
    33601 gaaaagaata ttaggagagg tagaagtcga aactatacca ggaatttcat cattttccaa
    33661 tatagcatct aatcagaatt ttccattagt catggataaa gaagctttag tggtaattcc
    33721 ttgtactatg gaagatgata agatagagta tgctttgcaa aattataatt caatagtatt
    33781 gatgaaggta tataaaaatt ttaaagaaat aataaaaaaa ttagaaaagt atgatttaat
    33841 agaacatgct attttagtaa gtaattcttc ccaagaaagc gaaaatgtgt ttacagattt
    33901 aaaagaagcg caccttgaag ataagatatc ttatttttct actatactag taaataaaga
    33961 taataaaata aaataggtga aagcaatatt taaaggagac ttaatatgaa tatagtggtt
    34021 ggaactaggg gtagtactct agcgcttata caaacagagt gggtaataaa tgaattaaaa
    34081 aagaagtatc cagaaattag ttttgagatt aaaatcataa agacaaaagg agatttaatt
    34141 caaaatgttt cactggataa aataggtgat aaaggattgt ttgtcaaaga aatagagcaa
    34201 caattattag atggaaaaat agacatagca gtacatagta tgaaagatat gccttcttat
    34261 ttagcagatg gactaaaatt tgctcatacg cctaagagag aagacccaag agatgttcta
    34321 atacttagag aaggatataa aaatttagat gatttgcctc atggagcagt aataggaaca
    34381 ggaagtaaaa gaaggaagtt tcaattattg aaacaaagac ctgatttaaa tatagtacaa
    34441 gttagaggta atgtggaaac taggatacga aaaataaaag atgaaaacat gcatggtatt
    34501 gtgttggcag catcaggaat aattagagct aatttgcaag ataaaataag ttcttattta
    34561 cctgttgatg ttgttattcc agcacctgcc caaggagctt tagctataga aattagaagc
    34621 aatgatagta cgatagaggg aatagtaaat tcactgaagg atgagaatac agaaatccaa
    34681 atattggctg aaagaggttt tttagatggt gtaaatggaa gttgtcatat tccaatggca
    34741 gcttattgtg aaataatcca agataaaata catcttactg gcttatatgg agattcagaa
    34801 ggaaaaaaag tagtaatcaa gtctatagat ggagatattt cttctcctag agagttaggt
    34861 ttaaagttag ctaaacttgt attgaaggag tatgagaatt atgaagggta aggtttactt
    34921 agtaggggca ggaccaggtg attataaact catgacttta aaaggtttag agtgtataag
    34981 aaaatcggat gtaatagtat atgatagatt agcaaatagt agttatttaa gagaagctaa
    35041 gcctgattgt gaacttatat atgtaggcaa ggcatcaagt aatcatattt tgccacaaga
    35101 agatataaat agaattatag cagaaaaagc taaagaagga aaaattgtaa ctcgtcttaa
    35161 aggaggagac ccttatgtat ttggcagagg gggagaagaa gcagagactt tagtagatga
    35221 agatatagaa tttgaagtag ttccaggtat aacttctgct ataggaggtt tatgttatgc
    35281 gggtattcct ataacacata gagaccatgc ttcgtcattt catgtaataa caggtcattt
    35341 gaagggtgat gatagtggag aattaaactg gaatgctctt gcaaataaca aaggtactct
    35401 tgtgtttttg atgggaattt caaacctaga gaaaataagt gaaaacttaa tgaaagaagg
    35461 aaaagataag gatacacctg ttgctcttat aagttgggca actagatata atcaaagagt
    35521 tgttacatct acacttgaga atgtttatga aactgctatt aaagaagaag taaaaccgcc
    35581 aactcttata gtagttggga gtgttgtagg acttagagaa aagttgaact tctttgaaag
    35641 taagccttta tttggaaaaa gtattgctgt aactaggtct agaaatcaaa atagtgtatt
    35701 ggtagaaaaa ataatggatt taggtggaaa tcctatagaa atacctacta ttaaggtaga
    35761 aaaaatacaa aataatatta acttagaaaa tgaaataaaa aatataaata agtataatta
    35821 tttaatacta actagtaaaa atgccgtaga aatcttcttt gaaaagatat atgaaatgaa
    35881 ttttgattta aggatattat ctaatttaaa ggtatgtgct ataggttctg ctacatcaaa
    35941 tgagttgaaa aaaagaggaa ttatagcgga tatagtacca aaaaaatttg tagcagagtc
    36001 actgtatgaa gagttagctc ctattttaaa tgataacgat aatatactta tacctagagc
    36061 agaaaatgct agagattatc tggttgacaa acttaaggct atttgtgaag taacagaagt
    36121 acatatatat agaacagtaa tagatgagga taaaaaaggt gagatattag atattttaaa
    36181 ttctaatgat atagattata taacatttac tagttcctca acagtaaata atcttgttga
    36241 aattatagga aaagaaaata ttaaaatatt agaaaaaata aaaacactat ctataggtcc
    36301 tataactaca gagacaataa atagtttggg aataaaattg tacaaagaat ctgctacatc
    36361 tactatagat tcgttagtag atttaattat aaaaaattaa ttttggaggc ttgaatatgt
    36421 taagaagacc aagaagacta agagcaagta aagcaatcag aaatttggta agagaaacta
    36481 aggtgaatgt agaagattta atatatccac tgtttgtagt agagggggaa aatataaaag
    36541 aagaaatcaa ttctttacca gatgtatatc atttatcaat agacatgcta gaagacgaaa
    36601 taaaagaaat aagtgagttg ggaattgaac atataatgtt atttggtgtt ccagatgaaa
    36661 aagatgagtg tgcttcacaa gcttttaatg ataatggaat agttcaaaag gcaattagaa
    36721 aggtaaaaga aataaattca gatataaatg taataacaga tgtctgtatg tgccaatata
    36781 caagtcatgg acattgtggg attttaactg atactggtta tgttgataat gataaatcat
    36841 tggagtattt ggctaaaata tctgtaagcc atgctaaagc aggagctgat atggttgctc
    36901 catctgatat gatggatgga agaatacaag caataagaga agctttagat gaaaatggat
    36961 tagaaaatgt tggaatcatg gcttatagtg ttaagtatgc ttcaaattat tatggacctt
    37021 ttagagaggc agctcattca gcaccatctt ttggagatag aaaaacatat caaatggacc
    37081 cagcaaatag caatgaagct ataatagaga ctgaacttga tatattggaa ggtgcagata
    37141 tacttatggt taaacctgca ttatcatatt tagatattat aagaagagtt aaagataatt
    37201 ttgacttacc tctagcagct tataatgtaa gtggagaata ctctatgctt aagtttgctg
    37261 tgaaggaagg tttattaaat gaagatgtaa ttcttgaatc aattacatct ataaaaagag
    37321 caggagcaga tataataata acttattttg ctaaagacat tgctaaactg ttgaaaaaat
    37381 aaattctagt agtataaaga atatcaaaaa gtataggaat tgtaattaac tattatacag
    37441 tagttttgtt tagacattta ttgaagaata atagaaacta atttacaatt tctatacttt
    37501 atttatgtaa ctaaataaaa tttggaggta gaagatgcta tatcctatta atttaaaatt
    37561 agatgagtta gatgtagtta taattggtgg tggagaagtt gcatatagga aatgtaaaaa
    37621 ttttttagag tttaacaaaa atgttactat agtttctaaa caaattttaa ataaatttta
    37681 tgatttaaaa ggaaatataa aaataataaa agatgattat aaagaaatat atataaaaga
    37741 tgcttctgta ataattgctg ccacaaataa tagagagtta aatatggaaa taggattata
    37801 ttgtagagca aaaaataagc tagtgaatgt agttgataat atagaaatat cgaactttac
    37861 tgttccatca tatataaaaa gaggagattt acttataagt gtgtctactg ggggcaagag
    37921 tccttcatta tcatcaaaga taaaaaaaga aattgaagag agatatactg aagattatga
    37981 ggagtattta aatgtattag gagatataag aaaaaaggtt ataaaaaaat acgaagataa
    38041 aagtaaaaga aaagatgtgc ttaatatgtt ggtaacactt gacctagaag aacttaagaa
    38101 gtttgatata taaaaaataa aataaaaaat gttaaaaagg tgttgacgga ttatttttaa
    38161 gatgatatag tgttacttgt ccttaagaaa agggcaaaca taaaaaa
//
LOCUS       DAEQJM010000032        37328 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.032, whole genome shotgun sequence.
ACCESSION   DAEQJM010000032 DAEQJM010000000
VERSION     DAEQJM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37328
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.032"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(544..1902)
                     /gene="rlmD"
                     /locus_tag="KRQ43_002043"
     CDS             complement(544..1902)
                     /gene="rlmD"
                     /locus_tag="KRQ43_002043"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH2742399.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAEGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVAKII
                     KQ"
     gene            complement(2077..3837)
                     /gene="pyk"
                     /locus_tag="KRQ43_002044"
     CDS             complement(2077..3837)
                     /gene="pyk"
                     /locus_tag="KRQ43_002044"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBH2742400.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEILTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(3889..4848)
                     /gene="pfkA"
                     /locus_tag="KRQ43_002045"
     CDS             complement(3889..4848)
                     /gene="pfkA"
                     /locus_tag="KRQ43_002045"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH2742401.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(5057..8626)
                     /locus_tag="KRQ43_002046"
     CDS             complement(5057..8626)
                     /locus_tag="KRQ43_002046"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBH2742402.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(8783..9730)
                     /gene="whiA"
                     /locus_tag="KRQ43_002047"
     CDS             complement(8783..9730)
                     /gene="whiA"
                     /locus_tag="KRQ43_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBH2742403.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(9747..10172)
                     /locus_tag="KRQ43_002048"
     CDS             complement(9747..10172)
                     /locus_tag="KRQ43_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH2742404.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(10241..11347)
                     /locus_tag="KRQ43_002049"
     CDS             complement(10241..11347)
                     /locus_tag="KRQ43_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBH2742405.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(11359..12216)
                     /gene="rapZ"
                     /locus_tag="KRQ43_002050"
     CDS             complement(11359..12216)
                     /gene="rapZ"
                     /locus_tag="KRQ43_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBH2742406.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIDEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(12247..12960)
                     /locus_tag="KRQ43_002051"
     CDS             complement(12247..12960)
                     /locus_tag="KRQ43_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH2742407.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYNDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFKLA
                     MKTISDSNLDISLVENIII"
     gene            complement(12964..13878)
                     /gene="murB"
                     /locus_tag="KRQ43_002052"
     CDS             complement(12964..13878)
                     /gene="murB"
                     /locus_tag="KRQ43_002052"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBH2742408.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(14151..14921)
                     /locus_tag="KRQ43_002053"
     CDS             complement(14151..14921)
                     /locus_tag="KRQ43_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH2742409.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            15239..16720
                     /gene="cls"
                     /locus_tag="KRQ43_002054"
     CDS             15239..16720
                     /gene="cls"
                     /locus_tag="KRQ43_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH2742410.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            17038..17535
                     /locus_tag="KRQ43_002055"
     CDS             17038..17535
                     /locus_tag="KRQ43_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HBH2742411.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLTTKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            17552..19438
                     /locus_tag="KRQ43_002056"
     CDS             17552..19438
                     /locus_tag="KRQ43_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBH2742412.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            19461..21242
                     /locus_tag="KRQ43_002057"
     CDS             19461..21242
                     /locus_tag="KRQ43_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH2742413.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRICMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(21382..23178)
                     /locus_tag="KRQ43_002058"
     CDS             complement(21382..23178)
                     /locus_tag="KRQ43_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HBH2742414.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQILSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLSPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVISHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(23392..24321)
                     /locus_tag="KRQ43_002059"
     CDS             complement(23392..24321)
                     /locus_tag="KRQ43_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBH2742415.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(24321..26138)
                     /gene="uvrC"
                     /locus_tag="KRQ43_002060"
     CDS             complement(24321..26138)
                     /gene="uvrC"
                     /locus_tag="KRQ43_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBH2742416.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVEAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(26397..29222)
                     /gene="uvrA"
                     /locus_tag="KRQ43_002061"
     CDS             complement(26397..29222)
                     /gene="uvrA"
                     /locus_tag="KRQ43_002061"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH2742417.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(29241..31211)
                     /gene="uvrB"
                     /locus_tag="KRQ43_002062"
     CDS             complement(29241..31211)
                     /gene="uvrB"
                     /locus_tag="KRQ43_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBH2742418.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(31398..32660)
                     /locus_tag="KRQ43_002063"
     CDS             complement(31398..32660)
                     /locus_tag="KRQ43_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBH2742419.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKVKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFDLKLDGVEKEAFDFIM"
     gene            complement(32723..34027)
                     /locus_tag="KRQ43_002064"
     CDS             complement(32723..34027)
                     /locus_tag="KRQ43_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2742420.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INRDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(34058..34918)
                     /locus_tag="KRQ43_002065"
     CDS             complement(34058..34918)
                     /locus_tag="KRQ43_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH2742421.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSMEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLILQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYIPLIIPFMTS
                     SFGIFLLRQNFMQISDETIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(34962..35831)
                     /locus_tag="KRQ43_002066"
     CDS             complement(34962..35831)
                     /locus_tag="KRQ43_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH2742422.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(35815..36885)
                     /locus_tag="KRQ43_002067"
     CDS             complement(35815..36885)
                     /locus_tag="KRQ43_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742423.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGKLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
BASE COUNT        11528 a         6652 c         4600 g        14548 t
ORIGIN      
        1 aactatgtag ttttaattat aaaaaaagat gaacaaaaat tatacagttt aatatggaat
       61 cagtaggtac atatgtatta ttaagaatta taaataataa aaataaattt tagtcaatct
      121 acaaaaacct tttaaattgt ctggaaatca cctcctcatt tgttataaaa acatacaaca
      181 aatgaagagg tgattttatg gtttttaaaa aaataattat aagtggatat gtgctttcac
      241 atgtttatca acatttgtaa tgcctatatt tgctaatgaa ttataatata aaaatattaa
      301 ataatattca actatagatt atgtaaatta tcctatgaaa aaaataagtt gtataaaatc
      361 tggcaactgt agattgacga tttcttttaa aattacaatt ataataagtt ttatagaatt
      421 aaaaataaaa ctttagagat ttttgataac attgtagact aaatttgcca ccgaaattac
      481 tttacagtgg caaatcggtg gcaaatacaa tatattatta gtatataatc tatataaaca
      541 ttactattgc ttgattatct tagctacagt ttccacatgt gtagaatgag ggaacatatc
      601 tacaggttgt gcctcaacac atttaaatcc gtgaacattt agatagtcta aatcccttgc
      661 taaagtagaa ggattacaag aaacatagac aattctttcc ggattcattg aaacaatagt
      721 ctctaatacc ttttcgtcac atccctttct aggtgggtct acaactacta cattggcagt
      781 cttaccctct ctatacatct taggtacaat ttcctctgcc tttccaacat aaaattcagc
      841 attatgtata ttgtttaatt tagcatttat cttagcatct tttatggcat catctataat
      901 ttctattcca taaacctttt tagccttttg tgccaaaaat aaagatattg tacctatccc
      961 acagtaaata tcaaaaacag tatcagtatc atttaaattt gcatattcaa gagccttatc
     1021 atacaatact ttagtttgga cagggtttac ttggaaaaat gataatggtg aaatctcaaa
     1081 cactaagtca cctatataat cgtttatttt tccatctcca tatataacta tattttctct
     1141 tcctagaata gcattcgtat ctttttgatt tacatttaca accaaagtct taaatccagg
     1201 tatattttcc ttaagcactg aagctaattc tttaagatat ggaagtttgt ttccatttgc
     1261 tactaataca accattactt ctttagttgt aaaacctatt tttgttacta aatgcctaat
     1321 caaccccgtg tgagtctttt catcatatat acttacctta taggccctta tatatgtttt
     1381 tattatttta acaattttat catttatctc atgttgtatt acgcattttt ctgtcgatat
     1441 tacatcatga gtcttctttt tatagaagcc aataattgga ataccattat tcttttgtat
     1501 tggaaattgt gctttatttc tatatctata tggattatcc attcctatag tgtcatgaac
     1561 ttctacatcc tctaacttac ctattctcga aagtacttgt ttaacttcat ttgttttcat
     1621 ttcaagttgt ttattataat ctaaatcttg tatctgacac cctccacaat ccctaagatt
     1681 gtcactacac actcttttca ccctgaatgg agacttttct attatctcaa caatatctcc
     1741 ctcagcataa tttttcttta ctttattaat cctaacttta actttatcat gtattaatcc
     1801 gccctctaca aaaactgtaa taccattgta ctttcctact cctactccgc cttgaccaat
     1861 gtctactata tctacaatat acatctcgtt tttcgaaagc ataaatcacc ctccaatcaa
     1921 tctattatat ttaaatcttt acaaactttt ttctttaaat ttatattaaa atattgctat
     1981 taattaaact atatttttta ctaagctaca atattttatt ttaccaaaaa aaaaggagct
     2041 tataaagccc cttagtaaat aaatttatta tttttcttat aaaactctag ttgaacctct
     2101 atataccacg cctcttgatg catccacagt tacaacttct ccatctttta ctagatttgt
     2161 tatatcagtt gcagacacaa taactggtat atctaaattt atacctacaa tagctgtatg
     2221 tgatgtcatt ccaccattct cagttactac agctcctgct ttttctatat aattgttcat
     2281 ttcagcatca gtagcagtag aaacaagtat gtcgccttca ttaaagtcta cacaagcatt
     2341 tccattcttt attatacgaa ctttaccttc taccgtttga gtacctacac ctataccttg
     2401 cacgatttct tcgcttatta catgaacctt tattaaatta gtagttccac ttactcctac
     2461 tggtactcca gcagttataa ctactaattc cccattatct atataatcag cttgtctagc
     2521 tgcctcaatt gccttttcta taacttcatc tgtatttcct gcaacagaag acttaactgg
     2581 atatactccc catgtaagag ctaatttatt catagtcttt tcattatttg tagtagctat
     2641 tattggagat tttggtctaa atttagatac cattctagca gtatatcctg aagaagtaga
     2701 tgttattata gctgatgcat ttaaatctac tgctgttgta caagttgcat ggcttattgc
     2761 atctgttaca gtaacattgt tagtaccatt ttcctttagt aatctatcat aatctaaagt
     2821 ctcttctgtt ctttttgcta ttgtagccat catttttact gcctctacag gatattttcc
     2881 agcagcagtt tctccagata acattatcgc atctgttcca tcatatatag cattggcaac
     2941 gtctgtaact tctgctcttg ttggtcttgg atttcttatc atagaatcaa gcatttgagt
     3001 ggcagtaaca actggctttg ctaattcatt acattttttt atcatcattt tttgaactat
     3061 tggcatctct tcagttggta tctcaacacc taagtcacct ctagccacca ttataccatc
     3121 agaaactttt aatatttcat ctaggttctc tacaccttct tggttttcta ttttagatat
     3181 tatttgtata tcagttgcat tattgttctc taatacttct cttattgcta gtacatcaga
     3241 tgcctttctt acaaaagaag cagctatata atctattcct tgacttattc caaactctat
     3301 atcacttata tctttaggag ttattgctgg taaatttatc ttaacaccag gtacatttac
     3361 tcctttatga tttttaacta ttcctgaatt ttcaacaaca caaactatat cttctccatt
     3421 tatttctttt actcttaagc caactaaacc atcatctatt agtatagaat ctcctgattt
     3481 aacgtcttca gcaagacctt tatagcttac tgtacacatt tctttagtcc ccataatatc
     3541 tttcatagtt atagtgaact tttgcccttc ttctaaaaat acctctgggt cttcaaagtt
     3601 acctgttcta atttctggac ctttagtatc taataatata gcaactggct tatttaattt
     3661 ttctctaact ttctttgcca tatcaattct ttctttatgt tcttcatgcg aaccgtgaga
     3721 aaagttaaat ctacacacat ttagaccatt ttgcataagt tgagttaaaa tttcctcact
     3781 ttgtgatgct ggacctagtg tacaaacaat ttttgtcttc tttacattat ttaacatatt
     3841 tgctcctcct gagatattat tccacagatt tatttttaat actaaaactt atatagataa
     3901 tatttttgcc atctcataag cttctttatc aaatactttc ttttgagcta aagcttcact
     3961 tatttctaaa tcaattattt tgttttcttt tattcctaca actctagctg attttccatc
     4021 taataataat tctactgctc ttactccaag tctacttgct agtattctat cagatacagt
     4081 tgggcttcct cctctttgga catgccccaa tacagtgact cttaaatctg ctcctgactc
     4141 ttttttaagt tccttttcta aatcactagc acttccgact ccttctgcta aaacgattat
     4201 actatgtctc ttacctcttt tttgagtagt ctttaatctt agagcaactt catctactgt
     4261 aatttctact tctggtacta ttatagtttc cgctcctcct gcaagacctg catataaagc
     4321 taaatctcca cagtgtcttc ccataacttc tactatgtta actctttcat gagatgatga
     4381 tgtatctctt atcttaccta tagcatctat aatagtattc attgcagtat caaatcctat
     4441 agtataatct gtatatgcta aatcgttatc tatagttcct ggtatgccta tagctgggaa
     4501 tcctaagtca ctaagttttt gggctcctgc aaatgaacca tctccaccaa ttacaactaa
     4561 gcaatcaatt ttatactttt taagaatttt tactgctttt aatctacctt cttctgtttt
     4621 aaattcttca catctggaag attttaatat agttcctccc ctgtgtataa tatctccaac
     4681 agaagataag ttcatttcag ttaaatcttc ttctagtaat cccttatatc ctctattgat
     4741 tccatatact ttgcatccat aatatattgc tgatcttaca accgctctaa tcgcagcatt
     4801 cattcctgga gcatctcctc cacttgttag taatcctata gttttcattt tttacctcct
     4861 tggattttat gtcaattttt tattataatc attgttattg tattctaatg gacttttttt
     4921 gtccctatat cactttttaa tcccatcaag actaaaaaaa ttaaatgtcc ttaaatgtcc
     4981 attttgtgat attatatcac aaaacggaca atatttttca tattattata atatatttag
     5041 atttttatat aaaaaatcaa gcttttactt ttatgttatc tttaggaagt aactcttcta
     5101 agttatttat aaattcatca catatacaag tcaatgcccc ggtcatttta tatgctttac
     5161 gtttaccatt tatattttca tccatagggt acaagtatat actgtcatta cctggatatt
     5221 gtttggctat ttctacaata ttattagttg tatcagtatc agacatacta tctattttca
     5281 aatacaattt tttaccactt tctggcttaa tattttctac atttctagtt cttcctgaat
     5341 tgtagtttct atctgcaaag tcagtatcat catttatatc ttttatctct ctagctataa
     5401 gttttgcatt ttcgccttct tttatactta atgttccttt tacatatatt atattatctt
     5461 cattcaaaat gacattatac ttttgtaata attgaggaaa aactattatt tctatagcac
     5521 catacaaatc ttctaattca ataaatgcca taatttcatt tcgttttgtt gttttaatag
     5581 ttttagttac aatcattcca cccattataa catctgtttc attcatttgt aggtatgact
     5641 cttcttcctc ttttaatgaa tttaattttc cattatccat agatgttttt tcttgtagtt
     5701 ctttttcaaa ttgtgataaa ggatgtccac ttacatacat tcccaagact tctttttcaa
     5761 ggttaagtct ctctctttct tcatactctt gccttttagg taaactgtat atttgttgaa
     5821 aatcactatc ttcctcacta tctccaaaag catcaaataa agaaatttga ccttgaacat
     5881 ttttctttct atccatagat acactttcta ataaactttc ataaccagcc atcagactag
     5941 ctctattttc acttatatta tcaaaagctc cacattttat tagactttct attactctct
     6001 tatttgtatc tttttggtct aatcttttga ctaaatctac taaatctaca aataatccat
     6061 tagattctct ttcagcgatt atattgttta ttatatttac accaacattt tttacagctg
     6121 ctagaccaaa tcttatattg tcgccttcaa ctgaaaactt tgaaaaactt ttgtttatat
     6181 ctggaggtaa tacatctatt tctagtgctt tacattctct tatatactca actaccttat
     6241 cagtatttcc cattacactg gttatcaatg ctgccataaa ttcaactgga taatatgttt
     6301 ttagataagc tgtctcatat gctaaaaccc catatgcagc tgcatgtgat ttattaaatg
     6361 catatctagc gaagtctatc atatcatcaa atattttatt agctatttcc tcttctacac
     6421 catttctgat acaccctgca atttctatat taccatcttc atcaaattta ccatgaataa
     6481 aatattgtct ttcttcttcc atcacgtcca tctttttctt actcatggct cttctaacta
     6541 ggtcacttcg tccgtaacta taaccaccta aatctctaac gacctgcata acctgctctt
     6601 gatataccaa acaaccatat gtaacttcca ttataggctt taatttttca tgtagatatg
     6661 ttacatcttt tgggttgctt ttatttttta tatatgcagg tatagaatcc attggacctg
     6721 gtctaaatag ggatattccc gctacaatat cttcaaaatt gtctggtttt agctgtttca
     6781 taaaacttct catgccagca ctctccaatt gaaacacccc tagtgtattt cctgatgaaa
     6841 gcatttcata tactttcggg tcgtcataat ccatctttga aaagtctatt ttttctgtgt
     6901 agttttttat aactctattt ttttctatta aatcaagagt atctcttata actgtaagag
     6961 ttcttagccc aagaaaatcc atctttaaaa gcccaagttc ttcaagtgtt gtcatagtaa
     7021 actgtgttgt gattgcatct tgatgtttgt acaaaggtac atattcatct acgggatttt
     7081 ttgatataac aactcctgct gcatgagtag aagcatgtct tagcattccc tctatctgtt
     7141 ttgatatatt tattatttct tttgtttccg ggtcttggtc atacaattct ttaagattag
     7201 gatttgtatc tagggcctta tctattgtca ttcctaaagc aaatggtatt tccttggcta
     7261 ccttgtcaac tttattgtag cctatatcca atacccttcc aacatctctt attgcagctt
     7321 ttgcacccat tgttccaaaa gttattatct gggctacatg gtcatcacca tattttctct
     7381 ttacataatc tataacttct tctcttctct cataacaaaa atctatatct atatctggca
     7441 tggatatacg ttctggattt aaaaaacgct caaataatag agagtacttt attgggtcta
     7501 tatcagttat cttaagtgta tatgctacta tcgaaccagc cgcactacct ctacctggtc
     7561 ctactataat attattttct ttagaaaaat ttataaaatc ccaaacaatt aaaaaatact
     7621 ctacataacc cattttttca attacatcta attcataatt taatctctct agtatctcat
     7681 tgctaggatt atcatatctc tcttttaatc cattaaaaca caactccctt aaataagttt
     7741 ctggtgtata tccttctgga acatcatact taggaagatg tatagtatta aaatcaaact
     7801 ccacattaca catatcagct attttcacag tattgtcaat agcctctaat gcgtatggaa
     7861 ataattcttc catttcttct cttgatttta agtaaaactc atcactacca aatctcattc
     7921 tatttgggtc atttaatgtt tttcccattt gaatacacat aagaacatca tgtattttcg
     7981 aatcttcttt atttacatag tgaacatcat tagtagcaac tagtggtata ccagtctctt
     8041 ttgataattt tactaaacca gagtttactt ctttttgctc aggtaaattg tgatcttgaa
     8101 tctccaaaaa gaaattttct tctccaaata tgtctctgta gtcaagagca aattgttttg
     8161 ctttttcata atttctattc attaaagcac gtgctacatc tcctgcaagg catgcagaaa
     8221 gtgctataat ccctttgtta tgttttttaa gttcttccat gtcaactcta ggcttatagt
     8281 aaaaaccttc tacgtatgaa gttgaaacta tttttattaa atttttatat ccttccatat
     8341 tcttagctaa cagaactaaa tgtccttgat atttgtcata gtttgggtct ttatctctca
     8401 atccacgtgc agctgtatag acttcgcacc ctataattgg ctttattcct tcttttatag
     8461 ctgttttgta gaaatctata acaccaaaca tacaaccatg gtcagttata gctattgagc
     8521 tcatgtttag ttccttagcc ctttttataa gttttttcac cctcgaaaac ccatcaagta
     8581 aactatactc agtatgtaca tgaagatgag caaaatcttt gttcattaaa tcacctcctg
     8641 ctttataatt ttaattttac cacaaatata tgtcctaaaa caaaaacaga gacttttatc
     8701 tcaaaatagg aattaacttc aacatatacc attatatgtt ataaattaat gcttattctg
     8761 agattgtccc ctcaatttat tgctatgatt tttttttcaa atctgttgca atttcttcta
     8821 tttttctaag tctatgattg actccagatt ttcctattgg tggttctaac atctctccaa
     8881 gttctttgag agtcatatcc tcatactcga ttctaatctt agctatctct tgtaaatttt
     8941 ctggcaaact gctaattcct atagtctctt gtatgagctt aatattttct acttgtctta
     9001 ctgctgcatt tactgtttta gaaaggttag ctgtctcaca atttactatc ctgtttacat
     9061 tatttctcat ttcttttact attttagtat tttgaagact taaaagagcg tggtgtcctc
     9121 ctataatact caacaaatct gatatttgtt cactctcttt gatataaaca acgtgattat
     9181 tttttctagc cacaatttta ctattaaaac ctaaagagtt tataagttct tttagagaat
     9241 ctgcaaactc ctcattatta gttacaaatt ccatatgata gttcttttct gggtcgctta
     9301 tagaacctcc accaagaaaa gctcctctta tgaaagctct cttacatcct tcatgcttaa
     9361 ttaagttctc tgaaattttg tttatagtaa aaaagccttc tttatcttca agtataccta
     9421 acttttttaa taacatttct gaacccattt cgcttgttac cattaataca taactgttat
     9481 ttctctttag catttgattc ttatttactg agattgtagt attgatatta aaattctttt
     9541 ttaataattt aaatacttta cgggctattg aatttaactc tgttgttatc tttagattta
     9601 gcttcttata tccaacgatt tgtatacttc cccctgattt aactagagct gataattcag
     9661 ctatattaca acattcattc ccagatataa ctcttgctag ttcatttttg gtttcagttg
     9721 aaaaagacat atctatcacc tattaactaa tttttcttta accttttttt tatttcttgt
     9781 aaggcaacct ttattatctc cttttcatca tcatacctag ctaggtctac cactctatct
     9841 agatggataa atttagcatc aataaagcct tcctcttttt gtggaatagt atccatattc
     9901 tttgcttgca tcaaatacca aaaaactgtt ttatgaactg ctctattttc atcccagttt
     9961 tctttgaatg tatagtgtat ttcacctaaa tatttcaata tatctgcttt tactccagtt
    10021 tcttcactta cttcacgtaa tgctgcctct tggttatttt ccccttcttc tacttttccc
    10081 ttgggtaaca cccaatctcc attgaacttc cttagtaaaa gaatcgtatt gccaaacagg
    10141 actacaccac cagcactaac ctcttctctc atcgatgttc actccttaaa actaacataa
    10201 tgataaggat ttctacacaa ttttttaaaa tcctttttta ctaacttttg ttgtaattat
    10261 gatttagggc taactcaata actatgttag atatatactt tgcatcatgt cttatataat
    10321 tattttttat ttcaattaaa ttcttctcta cggtttttat acccatctct tttaatttat
    10381 ctttttgctt tttatctaac aagacttgct ctgctccatc ttgtttatat aagtcaagca
    10441 tttcttctgg caatatctca ttatttgcga ttacataatc tattaaattc tcatcagtgt
    10501 gctttactat agcattaaca tgctctaata cattgtaccc ttctgtctca cctggttgag
    10561 tcattatatt tgctatatat acttttggag ctacagacga tttaatagcg tctacaatcc
    10621 cctctacaag taaattgggt attatactcg tatataagct tccagggccc ataattataa
    10681 tgtcagcatc gtaaatagat gcaataacat cctttaatgg tttgacatct tttggattta
    10741 aaaaaatttt atcaatagag cttttttgaa tttttgactc ttcaggtata ctagattctc
    10801 catttattat attgccattt tctaatttgg caactaaatt tacatcttcc aaagttactg
    10861 gtaaaactct tcctgttata gcaaaaattt cacttaattt atatacagct ttttcaaagt
    10921 ttccatacaa cccattcata gcagccaaaa acaaatttcc aaaactctga ccttttaaaa
    10981 gcccttctgt aaacctatat tgcataactt cattcattgt tggctctata tttgcaagtg
    11041 ctaatagaca gtttcttatg tctcctggtg ggagcattcc taagtcttct ctcaatacac
    11101 ctgaacctcc accatcatca gcaacagtta caattgcagt tatattttgc gtagtgtgtt
    11161 taagacctct taaaaatact gattgaccag tacctccacc tatcacaacc acatttggtt
    11221 ctctattttc aacaatagac ctttgaaata gttttacttt ttcatttttt gcttttttat
    11281 atataaataa cgatacaatt aatgcaatcc aacctaaaat tcctacaata ataagtaatt
    11341 tagccatgtt tgcctccatt atcgcaacat agagtctcta tgtttcttta caactctata
    11401 tcccttatta gataaatcct ccgctataag atttgttata gtaactgacc tatgtcttcc
    11461 acctgtgcat ccaacaccaa ttactagatg ttgttttcct tcatctatat attgaggtac
    11521 taaaaaatga atcatatcta aaagtttcac ataaaattct tcactgattt tagaattcat
    11581 aacataatct ctaacttctt tatcatcacc agttttagct cttaactctt caacataata
    11641 gggatttgga agaaatctta catcaaatac taaatctgca tcagcaagta taccatgttt
    11701 aaatccaaaa gatactacag aaatagttag gtttggatta tcttcaccag aagaatatat
    11761 tttctttatt tcttccttaa ggtctttagg tttcatgtta gttgtatcaa ttatacatgt
    11821 agataactcc tttaaaggtt ccattatctt tctttccatt tttatacctt ctggaatctg
    11881 catatctttt gccaatggat gatttcttct tgtcatttta tatctcttta acaatacatc
    11941 atcattacag tccaaatata ccatttcata ttcataattt tctttttcta aataatttaa
    12001 gctttcatga agcgcttcaa aaaactttct ccctcttata tctatcccta gagcaacttt
    12061 atcaatactt gaatttggtt gataacataa ttctgcaaat ttagttatca aagcaggagg
    12121 tagattatct acacaataaa atcccatatc ctctaaagct ctcattgtct cactttttcc
    12181 agatcctgaa agacctgtaa ctataacaaa tttcattgct aactcctccc ttttatctta
    12241 tgtttattat attataatgt tttctactaa cgatatatcc agattagagt cagatatagt
    12301 cttcatagct agtttaaaat caccaactct ttctggacaa tgtgcatctg agcctattat
    12361 aaatttattt tctagccctt ttattttatt taattgattt acattcaaaa aagaatggct
    12421 actatttatt tcaagtctag tatttgtctt ttttgctgtc tttgctactt cttctatata
    12481 cacatcgcct ttatctcctg gatgagtaat tataaaaata tcattattac ttatcgcatt
    12541 tattacagct tttgtattgt attcttttgc tttttcagtt ttaaaaatat agttattaca
    12601 atgatttaat aagcttctta atgatgttgg agtagaacca aaatgatatc cagccataat
    12661 ataatcaaaa tctctaataa atttatcatc catatctata ttgcctttat catctaatat
    12721 gttacactcc atacctaaaa gtatatttat atcattgtac ttatcattta aataatctac
    12781 ttcttctctc attttgagaa tatctttttt ctttacacca tatgcaatat gtttatagct
    12841 atggtcagat attcctattg tttttattcc tttagaaatg gctaccttta cattatcttc
    12901 aatagtccct ttgccatgac tatataatgt atgtgtatga taatcagcca gtattttcat
    12961 ttgttaatcc tctccaagta ttttgacttc ttcttccaac ataaccccaa acttggcata
    13021 tacagcactt tttataacat atattaaatc caaaatatct ttagcacttg cttctccttg
    13081 attgactaca aatccacaat gcttctcaga tacttgtgct cctcttaaag taagacctct
    13141 caatccagtt tcttctatta atttacctgc aaaatatcct gttggtctct taaatgtact
    13201 tcctgcactc gcaaaattta atggctgttt agttattctt cttgtcgcta aatcatccat
    13261 taaacttttt atttcatcat aatttccttc ttgtaattct agttctgctg ataaagctat
    13321 atatccgttt ttcgatatta tactttttct atacccaaat tccatctgtt catttgataa
    13381 ttcaaatata ttgccttcca tatccatcag tcttactgac ttcactatgt ccttcatttc
    13441 accaccatat gctccagcat tcatggctag tgctcctccc aatgtaccag gtattcctga
    13501 tgcaaactca aaccctttta attcttgctt ttggagagct ttacctaaaa ctgataataa
    13561 agctcctgac tgagcagtca tcctagtatc atttatctca taagaattga aattatcagc
    13621 taattctatt accactcctc ttattccacc atctttaatt aaaatgtttg aaccatttcc
    13681 aattattaaa tacggaatag attcttcttt taccaactta agtacatttt ttaattgttc
    13741 ttcagttcta ggtctaacta atatatctgc tggtcctcct accctaaatg aaatatgttt
    13801 tttcataggt tcatcgactt ttatatcctc tttacttaat atatttaata aatttatata
    13861 tatatcttga ttattcattg tatttcctcc caaattatac tgaactttag ctgtcattat
    13921 tatttaaatt acattagtat atagtattaa ctatattcaa taatatatga ttttgcttat
    13981 catatggatt ttatatttta agcttcttaa ttacaaacta tattcaataa atatataata
    14041 aagtaaaaaa aaaaaaataa caacatataa aagaatataa ataatttaaa aaaagcatca
    14101 atatcactga tatcaatgct ttaaaaggca atttaattcg tattatttat ctaactattt
    14161 ttgacatagc aaagataata aatccctcca actactatgg aacctccaac gatatttcca
    14221 agcgttacaa ataccaaatt agttataaat tgaaccatag ttatatttgc tcctaatgcc
    14281 attcccattg gtataaaaaa catgtttgca acactatgtt ggaatccgca taatacaaat
    14341 aacattatta ctgtccaaca tgaagccaat tttgacatta tatcttgaga tgctgtagcc
    14401 atccatacag ctaaaacgac taaaatatta caaagtattg cttttaaaaa cattgatgct
    14461 atagttgaat taaccttagc ttctgccaca gctatagctt ttgtagctgc atctcctgtc
    14521 aatgtagaag aataaaacac aagtgcaact agcagaattg aacctactaa atttgcaaaa
    14581 taaaccagtc cccagtttct taacattttt cctaatgtta tttttttgtc cataagtgca
    14641 atagccatta aggtgtttcc agtgaataat tctgctcctg ccaccactac aagcataaga
    14701 cctactggaa agaccatagc acttaaaaag ctagctaccc ctgggtctat cttgccaaaa
    14761 gtttgactaa ctatcatact ccccaatgcc ccaaaaccta taaatgctcc tccaaataaa
    14821 cctaatagaa ttgcattttg tgtcgaaatg tttgcttttt taatgcctgc acttatagtt
    14881 gcttgtgcag tttccccagg tgtcaagaat cctttactca taaatccttc ccccttaaaa
    14941 attatacttt cccttgtctt tttatggcaa taattatata ataacaatat gatatataat
    15001 aaattttatt aacataaaaa atatactata tacttatata tacttgtctc atataattat
    15061 actatttatt atataacaac tttgttaatt tcgaaataat ttatattgaa tttgaaaaat
    15121 ttaccttttg attatttatt ttacttttta attattgagg tattatatat aatagatata
    15181 tgtttgtgtt attatatata attacttatt ttaataaata tttgaaggag ggaattttat
    15241 gtttgatata tcatttttcg aaatgtcaat atatgaaata gcagttacta caatatatat
    15301 aattaatttc atggttatac taaaccttat ctttagagaa aaaagaaaca taaatacaac
    15361 tttaacatgg cttcttatat tagtattgat tcctgctctt ggattcatac tttatatagc
    15421 ttttggcaga aatatttcaa aaaacaatat gtttagattg aaagaaaagg atgataagat
    15481 aatcaaaagt aatatactag atactcaggt taaactccaa tctacatctg aaattgattc
    15541 agatatacat caacataagg atatgattta tgcattggct aattcaaata atgctcatta
    15601 taccaataat aacgatgtgt ggatttatgc tgaatctagt caatttttta acagtcttct
    15661 tgaagaactt aaaaaagcta aaaaatatat aaacatacaa ttttacattt tcaaagatga
    15721 caaaatcgga actgaaataa tagacattct tatagacaaa gctaaagaag gtgttgaagt
    15781 aagactttta tttgatgcag ttggtggtag aacactaaaa aatagtacac tttccagact
    15841 taaagaaagt ggtgttaaag ttggaagctt cttcccatca ttcttgaaaa ttgtaaactt
    15901 taacttaaac tatagaaatc accgaaaaat tgttgtcatt gatggtaagg taggatttgt
    15961 aggtggatat aatgttggtg atgaatattt aggtagaaat ccaaaatttg gtctatggag
    16021 agatacacat actaagctta ctggtgattg cgtaattgac ctaaatatga gattcatcct
    16081 tgattggaga tatacaacta aagaagattt agatttagaa aagtacttta tagaagaaga
    16141 tacaaattct aatcatcctt ctgaaaatat tgggattcag atagtatcaa gtggtccaga
    16201 tatatcagaa cttgatgaga ttaaatatgg ttaccttaaa atgattcaga aagctagaaa
    16261 gtatatatac atacagagtc cttatttaat acttgactca acttttatag atactttaaa
    16321 aatagcttgt ttatctggtg ttgatgtgag agttatgatt ccttctaaac ctgaccatcc
    16381 ctttgtatac tgggcatcat attcatatgc tggagaactt ttaaagtttg gagctaaaat
    16441 ctacacttat ggtcaaaatg catttttaca tgctaagaca atagttatag atgactctat
    16501 atgctctata ggaacagcta atatggatat cagaagtttt gagcttaatt tcgaagttaa
    16561 tgcatttatg tactcttcaa aaaaagcatt ggaacaaaga attatatttg aaaatgatat
    16621 tttaaattct aaggaaataa cattagatat atataattct aggtctactt atataaaaat
    16681 caaggaatca atttcaagac tattatcagc agttttataa atcttttatt ttataaaaat
    16741 tttacatttt ggtttatttt ttaaagtttt ttatatgtat tatttttttt ttattgaatt
    16801 tagctcattt tttttatttt ttttaactat tctgaattat tttatattat aatagactag
    16861 tatagttttt atttttaata ggtaactttt ttgcattgtt tttataaata aagaaattgt
    16921 tgtatattat tctttcttta ttgttctggt tttgttcacc cacataatgt tggggtcaac
    16981 tcatggttaa ttattttatg aaaaataata actttaaaaa gaaaaggggg atttgttatg
    17041 tgcgatttta tttcacacaa caagcaatta tttgacgaac tagatatatt tattgactct
    17101 cttacaacaa aggaaggtgc gttaatacaa gttctacatg aagcccaagg tatatttgga
    17161 tatcttccaa aagaagttca acttcatgtt gctagaaaac ttggagtagc tcctgcaaag
    17221 gtatatgggg ttgttacatt ctattcttat tttactacag aacctgtagg taagtataaa
    17281 atcagtgtct gtctaggaac tgtatgtttt gtaaaaggtg ctgacaaaat cttaagtgct
    17341 tttgaaaaac agcttggcat aaaagttgga gaaactacta gtgattttaa attttcttta
    17401 gagggtttaa gatgtttggg ggcatgtggt ttagctccag ttgttactgt aaatggtaaa
    17461 gtttatggta aagtgaaacc tgaccaagta agcgaaatat tagatactta tagagaatta
    17521 gaattgaatt gttaagaggg gtgaataaat aatgcgtaaa gtaaattcat ttgatgaatt
    17581 aaaagtttta gctgatgagc tgaaacctaa tcttagctta agaaaaaatt attctaagga
    17641 aaatgtatta agaagagaat tacttgtttg ttgtgatact ggatgtacct cttcaaacag
    17701 tctagaaata gttagtgaat tagaaaatga aataaagaaa tcaggaatcc aagataaagt
    17761 tagtgttcgt ttgacaggtt gttttggttt ctgtgctcaa ggtcctattg taaaagttta
    17821 tcctgataac gttttctacg taaaagttga gccatctgat gctgaaaaga tagttcaaag
    17881 ccacttaatt agaaatacag ttgtcgagga attattatat gaggaagaat ctttaagtaa
    17941 aaaagttgaa gaacaagaag aaatgtcttt ctacaaaaaa cagttacgta tagctttaaa
    18001 aaattgtggt cttatagacc cagatagtat agaagaatat attgccaatg atggttattt
    18061 agctctaggc aaatgtttaa cttctcttac tcctcaagaa gttattgcag aggtaaaaac
    18121 ttctggcctt cgtggtagag gtggtgcagg tttccctact ggctctaaat gggaagctgc
    18181 ttcaaaaaat ccagctggtc caacagataa aaagtttgtt gtatgtaatg ctgatgaagg
    18241 tgacccaggt gcatttatgg atcgatctgt acttgaaggt gaccctcata gtgtactaga
    18301 agctatggca atatgtggat acgctatagg ttctgataca ggatacatat acataagagc
    18361 agaatatcca aaatctatag aaagattaaa agtagccata gctcaagctg aaaaatacgg
    18421 tttacttggc gaaaatatct taggcactgg atttaacttt aaattagaat taaaatatgg
    18481 tgcaggtgct ttcgtttgtg gtgaaggtac agcgctaatg cattcaattg aaggtagacg
    18541 tggtgaacct agaatgaaaa cttatagttc ttctaagagt ggtctatgga aatctcctac
    18601 ttgcttaaat aacgttgaga cttttgctaa catacctgca attatactta agggtggaga
    18661 ttggtttgcc aacttaggta ctgaagattc tagtggtact aaagtctttg ctcttggtgg
    18721 aaaagtagaa aatgtaggac ttgttgaagt tccaatgggt actactttaa gagatattgt
    18781 atttgaaatt ggtgggggaa tccctgaagg taagaaattt aaggctgttc aaacaggtgg
    18841 accatctggt ggatgtatac caactgaaca tttagacact cctatagact ttggttcatt
    18901 aagttctatc ggttcaatga tgggctctgg tggtatgctt gttcttgatg aatctgactg
    18961 tatggtagat atagccaagt tcttccttga gtttactgtt gaagaatctt gtggtaaatg
    19021 tacaccttgt cgtataggta ctacaagatt attagaaata ttaactaaaa ttacagaagg
    19081 taatggtact ctacaagatt tagatgacct agaaaacctt gctgaaacta tacaaactgc
    19141 ttcattatgt ggtcttggta aagctgctcc aaaccctgtt ttaagtactc ttcaatattt
    19201 caaagatgag tatatagctc atgttgtaga taagaaatgt cctgctggta aatgtcagaa
    19261 cttactttct tactttataa cagatgactg taagggttgt acaaaatgtt ctagagtgtg
    19321 tcctgctggt tgtataacag gttctgttaa ggaacaacat acaatagata cttctaagtg
    19381 tctaaaatgt ggtgcttgta tagataattg tacatttaac gctataatca agaaataact
    19441 tatttggagg aggaataaca atgagtttag ttaatttaac tattaatggc aaacacgttt
    19501 cagcacctag tggaacttct atcttagatg ctgcgaaatt aataaatata aaaatacaca
    19561 acctttgtca tttacatatg aacgaaatag ataagcttga cacttgtgct tcttgtcgta
    19621 tttgtatggt tgagacagag agaggcttag ttccagcttg tggaacagtt ataaaggaag
    19681 gtatgaaagt tcagactaat agtgctaaag cattaaatgc tcgtagaact attgttgaat
    19741 tattgttatc agaccatcca caagattgtt ttgtctgtga aaaaaatgga gattgtgaat
    19801 tacagactat agctgctgat ttaggagtaa gaaaaataag atatcaaggt tccaaatctt
    19861 ttgcaggtaa agatacttct actaaatctt tagttaaaga ccattctaag tgtatattat
    19921 gtagaagatg tgagactgta tgtaatgaca tacaaacagt aggagcatta tctggagtta
    19981 atcgtggatt taatacttta gttagtacat tctttaactc tgatatggtt gaaacagagt
    20041 gtacattctg tggtcaatgt atatctgtct gtccaactgg agcattaaca gaagtagata
    20101 atgtacctaa actttgggat gttttaaata aaaaagaaaa gactatagta gtgcaagttg
    20161 ctcctgctgt aagagttgct attggtgaag agtttggatt agaaccaggg tcaatctcta
    20221 caggaaaaat ggtagctgct ttaaaagcac ttggatttga acatgtattt gatacaaact
    20281 ttggtgcaga ttttactata atggaagaag ctactgaatt tatagaaaga atccaaaaag
    20341 gtgaaaatct tcctatatta acaagttgtt gtcctgcatg ggtaaacttc ttagaacaca
    20401 attatccaga caagttaaac ttagcatcta gctgtaagtc tcctcaaggt atgtttggtt
    20461 ctatagctaa aaactactat gcacctaaaa tattaggaat caatcctgaa gaactttatg
    20521 ttgtatctgt aatgccttgt gtggctaaaa aatatgaagc ttcaagagaa gaattaagtg
    20581 aatctggaat actagatgtt gacctttcta taactactag agagttagct aaaatgataa
    20641 aagaagctgc tatcgattta cctaatcttc aagaccaaga ttttgataat cctctaggaa
    20701 aatctacagg tgctgcatct atatttggag caagtggtgg agttttagaa gctgccctac
    20761 gtacttcata tgagaagata actaataaga ctttagataa tgtaaacttc actaatgtta
    20821 gaggtcttaa aggaattagg gaagcaagta tagatgttga tggaactaca gttaatgtgt
    20881 gtattgtaaa tacacttaaa aatgctagaa agattatgga taaggtcaga agtggagaat
    20941 gtaaatacca tatcatagaa gttatggcat gtcctggtgg atgtgttgga ggtgctggtc
    21001 aaccttatca ccatggtaat actgaaatag ttgatagacg tgcaaatgcg ttatatgaaa
    21061 tagatagaaa taaggctatt cgtaaatctc atgagaatcc tgatttacaa gctatttata
    21121 aagacttctt tggagaacca aatagtgatg tagcccataa ataccttcat actcattact
    21181 ttgataagag ttgtgtctat ggagagtgtc cacaagaatg tgcttgtgaa gaagctaagt
    21241 agtcataaca aagtataaaa tttattctta aaaaaggatt gtcttaaaat acttttacgt
    21301 aatttaagac aatccttatt aatttcacaa attaaattat atttctaaat agacttattc
    21361 tttaattaac ctatctatta attaaagaat acctgccatt ctcataagtt gttttgcatt
    21421 tgtagtttta catcttccat cttttatctt atagtcaaaa tgaattttat cgtctacata
    21481 gtactctgag aaatgatagt ttacaacttc aacatctcca ctacctgaaa ggtcacatag
    21541 ctcaaagtca tgtgttgtca ccatacttat aacccagggt tttgataatt tctttactgc
    21601 ctcacttgct ccaataattc tatcagcaga gttagttccc ttaaaaattt catctactag
    21661 aaccaacatt ggcagttctt ttaaactata ttgaatcatt gattttattc taagaatctc
    21721 agcatagaaa gttgatattc cttgacttac atcatcttgt attctcatag aagtaaatat
    21781 agccatacag gtcgcatcaa aactcttagc gcatactgga gcacctgcat atgccagcac
    21841 taagtttaca ccgatacttc ttaaaaatgt tgtctttcca gacatatttg aacctgtgat
    21901 aatacaagtc tgagaattta attgtatcga atttgctatg acactttttt ctgctattaa
    21961 tgggtggtat acctcttcaa ctttcaatct tggagtatct tcatatttta ttactggaaa
    22021 acatgtattt tcctttacat gagaaataac tgttaaactt attagagctt caaattctcc
    22081 aatagattca aaccaatctc taatttgatt tccatatata cctttccatc gctccaaagc
    22141 ttctgcacaa tgatagttcc acatcaaaac accacaggca attatatata gtatctgatt
    22201 ataccttagg tttacagcat ttcctattga atttaattgt ttaacacctc ttgaaactcc
    22261 acttccctta gaaagtttat cttgtaattc tttcaaatat gcactctcaa acgtctcttt
    22321 ttctaaaacc tcaaacattt tttcatatac ttgtatactt ctactaaatg aaaataatgg
    22381 agaaagagtt tgcataagtc ttggatatcc aaaaccacta aaccctaact ggattataaa
    22441 aagtaaaaaa acaggtaaaa caggtaaaaa tcctaacata caaaatataa aagataagat
    22501 tgttgcagtt ggtagacccc aagtaaaaat atgcatccat tttggtatat acacattctt
    22561 attttctcca tactctataa acgattctat actactatct gaattatttt tttgctcttt
    22621 accaattata ttactgagta tttgaatatg aatagaaaaa tcatcttttg ataaaagttc
    22681 ttttatagcc ctctgtcttt ctaagattac attctcatct ggattttcat tccacaaata
    22741 tttggctaaa aaatttttcc cataagatgt attagctaca cagatatatt gatacaatga
    22801 tgctcttcca aataagtcta aatcttttgc ttgcgaattt tcatctttta agtattcttt
    22861 accatctatt ttaaattcct tccaaccatc tccaaatctc ttaatatact tatttaatac
    22921 ttcgctctta cttttaaaat atgtttcttc ttcttttact ttactatgaa taactaagag
    22981 tgctataaat attattattg ataaaactcc aacaaaaata cctactatat ttttattgta
    23041 aaatccaata gcaaaccctg ctatcactat caaaaaagat attaatcttg ctgtacttat
    23101 gttatttgac tttttactta agagcaattc tttttcagta ctactttcta aaagtttact
    23161 aaaatattct attcccataa aaaattccaa ctttcttgtt atataatgaa actcaaatat
    23221 aaaattaatc tagtattatt ataatctaac actgtacttt aaattatcct tatataatat
    23281 atcttattaa taaacattat atatatacaa cttgatttta atttataagg tgtaggacat
    23341 aatcctaatc aatatttaat taaatgatgt gtagttcact attattcagt actacttagt
    23401 atcgattaat tttgataatt ttttagtaaa ttcttgagct gcatcgtatc ccattcctct
    23461 ttgtctaaaa ttcattgctg ctacttctaa tatcatagca gtatttcttc caggtttaac
    23521 aggtacaact aatttctcta cattaacacc aagtatttct tcgtattctt tatccagtcc
    23581 tagtctatca taatacttag tttcatccca agcttctaaa tgaactacta aatctatcat
    23641 tttagaattt ttgattgccc ctactccata taaacttcta acatctatta ttcctattcc
    23701 tcttatctca agaaaatgtc ttattagttc aggtgactga cccacaagca tactttcatc
    23761 taattttctt atttctacag catcatctgc aactaatcta ttaccccttt gaatcagttc
    23821 taatgctgtt tccgactttc ctatactact ttcacctttt atcagtacac ctataccata
    23881 aatatctact agcaccccgt gaattgttgt gtgtggtgct aacttattat ccaaatagtt
    23941 tgacagtcta tttataagtc tagtggtatt tctatttgtg ctcaaaagta ttcttttata
    24001 ttttttagcc ttttcaatta catctggctt gatttccaag tctctagaaa ttattaacgc
    24061 tggtatttca tatgagaaaa atctatctag tacttcttct cgaatatgac tatccattaa
    24121 tccaaaaaaa ttatattctg tctttccaac tatttgtatt ctttcatatg caaaataatc
    24181 aaaatatcct gcaaactgta atcctggtct atttatatct tgagagtaga cataataatc
    24241 tacatcatca ggcatgtata ctacttttaa cttcaactct tttattatct ctcttattga
    24301 tactttattg ctagtttcca ttaattttct tcctttctaa aaaaattata aacattatct
    24361 gcaatgcttt tattcattcc atctacttct aaaagttctt ccatagtagc tttttttata
    24421 gcctctacat ctttaaagtg atttaataat gatttctttc ttttttcacc tattccttgt
    24481 atatcatcta agatagattt tgtcaaagct ttatttctta gacttctatg atatgttatt
    24541 gcataattat gaacttcttc ttgtatacta gcaataaatc tatataaatt agttgtttta
    24601 tctagttcta tttctttttc tttgcatatc aatcctttag ttctatgctt atcatctttg
    24661 tacattcccc aaagaggtat atctacatca ttgagttcta gtactttttt tactgcacta
    24721 acttgtcctt ttccaccatc caacaatatc aagtcaggta aatttccatg ttttaatctt
    24781 ctatctacaa tttcagccat agaatcataa tcattaggtc caataactgt ctttatttta
    24841 tatctcctat attccttctt atctttttta gcattcgtat acactaccat agaaccaatc
    24901 gaatctacac cttgtatatt tgatatatca taagcctcta ttcttattgg caacttttct
    24961 agatttaata tttgttttaa ttcttccaat gctccaatac ttttttcata ttttctttta
    25021 ttcatatcag aaaatttttc aagatattct acagcatttt tcctaaccat ttcaactaag
    25081 cttttcttct ctcccttttg aggaactctt attgttactt tttgcccctt tttagatgac
    25141 agccattctt ctaatataga actatcttct atctcatctt ctataattaa ttctttaggt
    25201 atatactctt gttcattata aaattgtttt acaaatgaac ttaatataga agctcttgga
    25261 ctatccatta caccttctaa tataaaatgt tccctaccta caatcttacc atttcttata
    25321 aaaaatacct ggacacaagc ttcattatga gctcttgcca ttgcaaccac atcttggttt
    25381 aagtcactta cagtagcatc tattttttgt ttctgtatca tctcttcaag gctctttatc
    25441 ttatccctat atacagcagc ctcttcaaat ctaaagttca tagaactctc attcattttt
    25501 tcctttaaaa gttccatcaa tttttcttct ttaccagata aacacattat aatctcttct
    25561 atcatttttc catactcttc tttagaaaca tttcctgtac aaggtcctaa acatttattt
    25621 atgtgtagat ttaaacaagg tcttgtctta ttctttattg ctttatctat atctatttta
    25681 cagcttctta ttggatacgt actacttata agctccaagg tatcattcac agcagttata
    25741 ttggtatagg gtccaaaata ctttgcctta tctttaagaa ctcttctaac ttttaagatt
    25801 cttggataat cttcattcgt agttactttt atatatggat aagttttatc atctctaagc
    25861 actacattat actttggtct gtatcttttt attaaattac attcaagtat taatgcctct
    25921 aactctgaat ccgttataat atactcaaac ttatatatat tcttaaccat agattttact
    25981 ttagatgtat ggttttttga agattgaaaa tactgcctta ccctattttt tagagatatg
    26041 gcttttccca catatattat atggtcgtat ttgtctttca ttaaatatac tccgggctca
    26101 gaaggtaatt tttttaaatg ctcttgtata tcaaacatct cgccctccaa aacattaaat
    26161 tttatactaa aattataccc taaaatatga attttaaaaa gttatacaat ttccagtgct
    26221 ttagacaagt taaagtccat attcccttct ataattgatt tgaaaacaat tttaaccatg
    26281 aagagtaata tggactttac tttgtattac tatttacaac ttatatttga ctaatttact
    26341 tataacaaaa cagtttatcg tatatctgct ctaaaatttt tcacaattta tataacttaa
    26401 gaaaaatatt tctttaagaa ttgacctgta taagaaccat caactttaga tacttctttt
    26461 ggtgttccag ttgcaactat agttccaccc ttatctccgc cttctggtcc taagtctatt
    26521 acataatcac aagtctttat aacatctaaa ttatgttcta tgactataat tgtatttcct
    26581 gtatctgcta gtctttgtaa tacttggatt agcttgtcta catctgccat atgaagtcca
    26641 gtagtaggtt catctaatat atacaaagtc tttcctgttg gtcttttact aagttcagca
    26701 gctaatttta tacgttgcgc ttctcctcct gataattgag ttgaaggctg tcctaattta
    26761 atatatgaaa gtcctacatc cattaaagtt tctaattttc tttttatatt tggtatattt
    26821 tcgaaaaact caacagcttc ttccacattc atatctaata tatcagatat agttttatct
    26881 ttgtatttta cttgcaatgt ttctctattg tatctttcac ctttacaaat ttcacaagga
    26941 acatatacat ctggtaagaa atgcatttct atttttatta ttccatcacc cttacaagct
    27001 tcacatctac caccttttac attaaaacta aatctacctt ttttataacc tcttgcttta
    27061 gcttcattag tagatgcaaa aatatctctt ataaaatcaa atacacctgt ataagtagca
    27121 ggatttgaac gaggtgttct tccaatagga ctttggtcta tatttataac tttatctata
    27181 ctttcaattc cttttatctc cttatgctta ccagctcttt gcttaagtct attcacttta
    27241 cttgcaacac ctttgtaaag tatatcgttt attaatgtac tttttccaga acctgaaaca
    27301 cctgttatgc atgtaaactt acctaatggg aactttacat caatattttt cagattattt
    27361 tctgatgctt taactatttc tataaaactt ccatttcctt ctctagtagt ctcaggaagc
    27421 aatatttgtt ttttaccact taaatattga cccgttattg agttctcatt ttcaattatt
    27481 tcatctaaag taccctgtgc aactatttca ccaccatgta tacctgcacc tggaccaatg
    27541 tctataacat aatcagcttc tctcattgtg tcttcatcat gctctacaac gattaaggta
    27601 tttcctaaat ctgttagatg tctaagagta gttataagcc tatcattatc tctttggtga
    27661 agccctatac ttggctcatc aagtacatat aaaactccaa ccaatgcaga acctatttga
    27721 gtagctaatc ttatacgttg cgcttctcct cctgataaag ttccagcttt tcttgataaa
    27781 tttaaataat caagacctac atctcttaag aacatagctc ttccttttat ctcttttata
    27841 atctcatgag ctataaatct ctgtttttct gtaagattta tattttccat aaagtcaatc
    27901 aattcattta cagataagtt tgtaacttcc attatatttt ttccatcaac taaaacagat
    27961 aaaacttcct ttttaagtct catcccttta cactttggac atggtctctc tgccatgtat
    28021 tcttcaatct tatctctcat gtaatctgaa ttagtttctc tatatcttct ctctaagttt
    28081 actattacac cttcaaagta tgatttataa tttctagttc ctccaaattt tgactcataa
    28141 gtaaactcta caattatatt atctttacca taaagtaatt cctccacaaa atcatctggt
    28201 aaatctttaa acggtgttgt caaagataca ttaaaatgct ctgctaaact ttttatcatt
    28261 ttactgtaat aagtgtcatc attaacacct gttgaacccc atgctgccac tgcaccttgt
    28321 tttattgata aatctttgtt tggtactact aattctgggt caacttcttt actttcccca
    28381 agaccattac aaacatcaca agcaccaaag ggagcattaa atgaaaacat ccttggagat
    28441 aattcttcta tgccaattcc atgttctggg catgcaaatt tagttgaaaa aagaatttct
    28501 tctccatcta ttatttgggc tattacaaga ccatcagata gcttaactgc agtttcaatt
    28561 gaatctgcta gtcttgattc tattccatct ttaattacta ttctgtccac tacaacttct
    28621 atattatgtt tttgattttt atttaagatt atatcatcac taacttcata gttctcacca
    28681 ttaactctaa ctcttacaaa tccttctttt ttgatattat caaagacttt tttatgtgta
    28741 cctttttgtc ctctaacaat tggtgaaaga atttgtaatt tcgttctatc tggaaaatct
    28801 agcattttat caactatttc ttgaatagtc atctgactta ttttttcacc acatgtaggg
    28861 caatacacat ctcctactct tgcaaataat agtctcaaat aatcatatat ttctgttact
    28921 gttccaaccg tagaacgtgg gttttttgag gtagtcttct ggtcaattga gatagctggt
    28981 gataaaccct ctatatattc tacatttggc ttttccatct gacctaaaaa ttgtcttgca
    29041 taagcagata gactttctac atatcttctc tgcccttctg catatattgt atcaaatgcc
    29101 aaagaagact tcccagaccc tgacaaacct gtaaaaacaa taaatttatc tcttggtaat
    29161 tctaaatcta tattttttaa attatgttct tttgctcctc ttattataat tttatcttcc
    29221 ataatgttgt ttttaccttt ctatttttcc aatttttctt ctaattgttt cactttatct
    29281 ctaagttctg ctgctctttc aaattgtaag ttttgagcag cttccatcat ctctgatttt
    29341 aatttatcta tattagctct tatttcgtct ttatcatctg tatcagatat tccatataca
    29401 acttcttcct ctgcaacctt agtagcttct atactatctc ttatattttt ctgtatagtt
    29461 ttaggaatta tattgtgctc ttcattatat aaattttgta tatctcttct tctctttgtt
    29521 tcatcaatag cattttgcat tgagtcagtt atcctgtctg catacataat tactcttcca
    29581 ttttcatttc tagctgcacg tccaatagtc tgtattaaag ctgtttcgga acgtaagaaa
    29641 ccttctttgt ctgcatctaa aattgctata agtgaaactt ctggtatatc caatccttct
    29701 ctaagtaagt ttattcctac aaggacatca aacttcccta atcttaaatc tcttattatt
    29761 tctgttcttt ctaatgtaac tatatctgag tgtaaatatt taacttttat ccctatttct
    29821 ttaagatagt tagtcaagtc ctcactcatt tttttagtta aagtggttat aagcactctt
    29881 tcattttttt ctatagtttt agttatttct cctaccaaat catctatttg attatttata
    29941 ggtcttactt ctacaattgg gtctaaaagg ccagttggtc ttattatctg ttctgctatt
    30001 gtctctgagt gttgaatttc ataaggtcct ggtgtagcac ttacaaacaa catttgattt
    30061 atatttcctt caaattcttg aaaatttaat ggtctattgt caagtgcaga aggtaatcta
    30121 aaaccattct ctataagtga tgtttttcta gacctgtctc ctgcatacat acctcttact
    30181 tgtggtatag tgacatgtgc ctcatctaca attatcaaat aatcatctgg gaagaaatcc
    30241 attaaagtat atggtctttc tccttctgac cttcctgtaa tatgtctaga atagttctct
    30301 atcccctgac aaaatcctat ttcctttaac atttctatat catacttagt tctttgttca
    30361 attctttgtg cttctaatag cctatcattt tccttgaaaa atttaatttg ttcttgaagc
    30421 tcgttttcta tttctacaat tgccttttca attctttctg gcgttgttac atagtgagat
    30481 gctgggaata taacaacatg atttctagta ccaacaatct tccctgttac ataatcaatt
    30541 tctgttattc tatctacctc atcaccaaaa aattctattc ttattgcttt ttcatcatta
    30601 ctagctggga atatttctag tatatctcct ctaactctaa aggtacctcg tgtaaagttt
    30661 atgtcatttc tttcgtattg tatctctatt aaccttttta ttacatcatc tctgtctctt
    30721 tgcatacctg gtcttataga taacataagt tctttatagt cttttgggtc accaagtcca
    30781 tatatacaag atacagatga tattattata gtatctcttc tctctaaaat agatgctgta
    30841 gcagaatgtc gaagtttatc tatttcatca tttatgcttg catctttttc tatataagtg
    30901 tcactgtgag ctacatatgc ttctggttga taataatcat agtaacttac aaagtattca
    30961 actgcattgt ctgggaaaaa ttctttaaac tcactgtaaa gttgtgctgc tagagtttta
    31021 ttatgagcca ttattagggt aggtttctta acttgttgaa tgatatttgc cattgtgaat
    31081 gtttttcctg aacccgttac acctaataat gtcgaaaatt tctcatttct atttatagaa
    31141 tccactattg atttaatagc ttctggttgg tcacctgtag gtttgaagtc tgattttatt
    31201 ttaaaatcca tagtatcact ccttttttcg aacattagtt cctgacatgt attattatat
    31261 cataccttta taaaattgtt taagttattt taaatatttt acccatttaa attttactta
    31321 aatctaaaac ataaaaaaag acttctatct ttgcaataga agtctataat tcatggaaaa
    31381 taaatacttt attcaactta cataataaaa tcaaatgctt ctttttcaac tccatctaat
    31441 tttaaatcaa acatttttaa tatagttgct gcatgtgctc tcaggtctcc ttcttctata
    31501 accacaccac ctttaatatt tggtccaaaa gctataaatg gaggtctatt acctttagta
    31561 ggtaaatgac catgtgtcgc aacagcaaac ttgtaatctt ttatatctga atcttttata
    31621 atacttcctt cgaaatcatt tccaaatgaa attccttcaa gaccttcaat caccatttca
    31681 aaatcacctt caagaccaag gttagatgct tcctctttgg taaaaatatt ctctatgaat
    31741 aattcttctt taaattcttc aagcagttct cttaattctg ttaacctatc taagttattt
    31801 actattattt gagctgatat tccagaagaa tttacatagg catcaaaatc cttaacttct
    31861 ccattttcaa cttttataaa tccatttgat ttaagcaaga catttggatt tataacttta
    31921 tcaactctaa gatgaccatg gtccccaagt attataaaat ttgtatcttt gtatgtacct
    31981 gcatcctttg tagcctgaat aatatctcct agccatttat cattcatttt taatgcttta
    32041 tctacttcgt cattaaataa gccataatta tgtcgtgtat ggtccaatgt agctaaatgt
    32101 attagcatta aatctggttt atattccttt attatatcta ctgaacagtt tactccaaat
    32161 aaatccatgt tgggttctaa tttccaatca atataatgac aatgtctatt gtaaataccg
    32221 tccattataa ccttactgga gcttcgttca aaagtttctc ttgggtcatc ttctctacta
    32281 ggagcccata tttctgcaat attataatct atatttggat ttgctcccat tacaggccat
    32341 aatacactag aggtagttag attattttct tttgctacat ctataatagt ttttactttt
    32401 atgtcctttg aataccagta ccagtcttta ttttctttat ttgggtcaaa tttttcatta
    32461 tgatatatac catgtttttt aggatatact cctgtaacca tactagtatg acacggatat
    32521 gtcagagtgg gataaacaca atttatattt tttactatgg agcaattttc tagtatagat
    32581 ttaaagtttg gtagattttt tacaaattcc aagtcttttt caaataaaga atctactgat
    32641 aatactataa cctttgtcat ttacattacc tcttcattta tatattattg aatactttta
    32701 atcaacttac aagtctatat aattatttat ttgttttatc tattactgct tgcattgcag
    32761 aagttccttt gcttactaca tcttttggat ttgcatttaa atcagtaagc ccctttttaa
    32821 tctcatccat tagcttatca gttgcttcct tgtatccatt taacattgga agtgcaacag
    32881 catattgtaa ttggtcagtt gcaaccttat attgaggttt ttctttatat aatgtttgta
    32941 acttttctga gtttgttgca tcttcagttg ttggtaagta tcctgttgat gaactaaact
    33001 gaacgatttt atctgtttgt gtcatccatt ctataaattc tgcacttgct tctttttctt
    33061 tatctgttcc accttcaagc ataactagat tagctccacc tgtaggagtt gcgtattttt
    33121 gattttttgg taggaatgct gttgatattt caaacttacc ttctgtttgt tgcataagtc
    33181 ctgctaaatc tgctgttgat gtaaatatca tacctacttt accatttaca aaatcttgtt
    33241 ttgctacgtc ccaggcatta taatcttctc caggaggcat tttcattatt ccagctttca
    33301 tcatatcttg ccagaattta actggtgctt gtcctgcctc attattaaat gctacttttt
    33361 taccattagt tatttctcct ccactttgca ttaccatagc ttcatagaac caaatatcta
    33421 ttggtgtttc aaaaccataa gtatcttctg atttatttgt cattttacta gcgtaatcct
    33481 taagctcttc ccatgatttt ggacctgaag ggtcaagacc tgctttagtt gccatatctc
    33541 tatttatgta taatattggt gtacttctat taaatggcat accaacaaac ttatcctcat
    33601 aatatgaatt tgttaaaaga ccagaaaaga atctttcttg atatgtttta tcaaaatatt
    33661 tactcatatc tactaaagca cctgctgatg cgaatgtacc tgtttgagtt atttctaata
    33721 atgttacatc tggttggtct ttagatgtta aggctgcctg tagttttgtt gcattttcat
    33781 agtaatcttt ctgttttaac atatttactt gtacatcctt atgttcacta ttaaattggt
    33841 caaccatttt ttgagcagtt tctccattag ttccacctaa aggagcccag aaatctatct
    33901 tcgtaatatt gctatcagtc ttttctcctt tagatgcatt tgcatcatta gaatttgaac
    33961 acccaactaa agaacctaat aataatgtta ttgctaatcc tgttgctaat tttcttttaa
    34021 gcttcatttt catcctccaa atttagtctt taatttttta ttttattcct gaatacataa
    34081 aagcttcttt tactttttta ttcgcaaata tataaacaag aattattggt aaaattagaa
    34141 ttatatttcc tgccattatt acattccatg cagtaattcc ttctgaagat ttaaggagcg
    34201 caactcctat tggtaaagtt cttattgcat ctgtatttgt cattactaag ggccagaaat
    34261 aattattcca atggtatata aaattaaata atataaatgt tattactgct ggttttgcca
    34321 taggaaccat tattctaaac attattttta agtcagaagc attatctagt ttagctgctt
    34381 caatagtttc atctgaaatc tgcataaaat tctgtctaag cagaaatatc ccaaatgaag
    34441 atgtcataaa tggaattata agtggaatat aagtatttat aaatccaaac ttactcatca
    34501 tcatatagac tggtagaaaa gttacttgtg gtggaatcat aagtcctaca agcaaaagcc
    34561 caaataacat tttttcacct ttaaatttaa tcttagaaaa tgcatatgct gctggaacca
    34621 taactaaaaa ttgtaaaatt aaaacacttc ctgttacaaa tacactgttt agtaaatatc
    34681 taaaaaatgg acctgaatgc catgctgtac tataattttc taacactata tcatttggta
    34741 taatagtagg tggtaattgc atcatttctt gtggattttt aaaggatgtc gatagcatcc
    34801 atataaaagg gaatataaat attgcagata aaagtaatag aattaatatt tccattgatt
    34861 ttgatgctat tttttttata tcaactttgt cttttttgat aggttgtata atatccattg
    34921 tctcctcctt ttggataaat cttataatat ctactttttc tttattgata atgaactttc
    34981 tttgataaga gtctaaagtt agcatatgta gcaatcataa ctatagctaa caaaaacata
    35041 ctcgctgcac tcgcttgccc tatgtcatag tatataaatc cagactcata tatataataa
    35101 gataacatgt tagttgaacc cactggccca ccttgtgtca ttatacttat ctcatcaaat
    35161 acttgaaaag atgcagttgt tgttgttatc ataagaaaaa atattgttgg tgataatagc
    35221 ggcaatgtca ctttaaagaa attcgttatt ttgtttgcat tatctaattt agatgcttca
    35281 tatatatagt ttggtatgga tttaagacct gataatacta ttaagatatt gtatccaaga
    35341 gtcttccata ttcctattag aattagtgac attaaagctg aactttcact tgaaagccac
    35401 tttgatgttg gtaaatgtaa tgtcgatagt atccagttta aaaagccata ttgtggctcc
    35461 ataatccaaa gccacaatac agctacagat actagtgaaa ttacatgtgg tgtaaagatt
    35521 atactttgcg ttaaattgtg tattatagaa tttttattta gccaaacagc aagtactatg
    35581 gctagtgata tagatatagt caccataaaa aaagtataaa ttgcagtgtt cgttatagtt
    35641 tgtataaact ctggattctt taaaagttct gtataattgt ttaagcctac attttcaaag
    35701 gttgaactaa gaagactacc agatttgaag cttagagata tcgtcttaat tattggatag
    35761 actataaaca ataaagttcc tataatagca ggtgttatat ataaatatgc tttattaaat
    35821 tgctttttca taaatatctc ctttaatttt agaatacata cttttacata cttttacatc
    35881 ttctattctt tctccatttt tatcaaaata atataaatct ttttctaata cacttattct
    35941 taaagttctt ccaatatcaa atatatcatt ttccgttttg actcttattt ctctattaag
    36001 aacagataaa caatatatag tttcatttcc caacacttct ttagtcacaa cttttccaaa
    36061 taggctaaat acatcatcat tttttccatc tatgtttata ctctctagtg ttgctttttc
    36121 tggtctgaat ccaaatttaa tatcattttt tatatctagt atgttcatac aaggactccc
    36181 tataaattga gctacaaata aattcttagg attttgatat atcttctttg gagaacctat
    36241 ttgcattatc tttcctttgt tcattataac tatcttatct gccattgaca ttgcctcaac
    36301 ctggtcatga gttacataaa caaatgtaga ttttagtttt tgatgtaatt gtattaattc
    36361 tgttctcatt tgatttctta atttagcatc taaatttgac aatggttcat ccattaaaaa
    36421 tacctttgga tttttaacca tagctctagc aagtgccact ctttgtcttt gacctccaga
    36481 taagttgcct ggtttcacat ttaaatattc tctcaatcct actacatcaa taacttctgt
    36541 tataagtttt tctctttttt ctttttctac ttttttgttt ttaagaccaa attctatgtt
    36601 ttctctaaca gtcatatgtg gatataatgc ataattttga aataccatag ctatatccct
    36661 tttactagca tccgtttttg taacgtcatt ttcttcaatt tttaacttgc ctgaagttat
    36721 atcttcaaga cctgcaatca ttcttaatgt agtagattta ccacatccac ttggacctac
    36781 caatactgta aaagaaccat cttctatagt aagatttaaa ttttctataa ctgtattttt
    36841 tttattataa gattttgtta cattttctag tcttatatct gccattttta tcctcccaaa
    36901 atatttaatt taattctacg atttacttat agattaataa tactcttaat ttgtaaagga
    36961 tatattaaga caaagtgaat atatagtaaa cttattaaaa taaaggttaa attataaaca
    37021 ttttttgtta aatatactga agttaagatg atatacagct tatgttagct ataattttct
    37081 atatttttca tattcatggt ttgctatcac aatgtgattt taatttatga agagtcatat
    37141 aaaactattt attttttata taatttggtt tgaaaataaa aaagacctct atgggggata
    37201 gaggtcttta agtgggggag attgagtaat ttatttttgc tatattaagt tttacaatta
    37261 tattatgtcc caaatttaca aggtttaaac ataaaaaata aaactttttt aatttttata
    37321 aatttacc
//
LOCUS       DAEQJM010000033        37165 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.033, whole genome shotgun sequence.
ACCESSION   DAEQJM010000033 DAEQJM010000000
VERSION     DAEQJM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37165
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.033"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..1849)
                     /locus_tag="KRQ43_002068"
     CDS             complement(<1..1849)
                     /locus_tag="KRQ43_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH2742424.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAITVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSHGGGSSSSKVDKVVLKNTITAANKLYNEAIEGTNVGEYKVGSKAIYKTAIDKAQAI
                     LDKSGVTQKEVNDAVTALNTATDTFKAGKVVAVDKTALQDAVTAATALHA"
     gene            complement(2274..3668)
                     /locus_tag="KRQ43_002069"
     CDS             complement(2274..3668)
                     /locus_tag="KRQ43_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2742425.1"
                     /translation="MTKLNKKLSISISIVVVVVYIISIIINSMFIHRYYLHEKRNILD
                     NVENEIKDKDIDKLKSDITLIEEKNNIDIVYIELDKNHKDKGNIDKINQDLLNAFWKK
                     GLSLNKFWIEENSLNNIDKKSINKIYNQGKTKYSLLVKFIKKDNYLFAISIPIEHSEE
                     TIGIVNRFNIIMGIFSVVIITILTFILSNRVIKPMERLKFLSKDISELNFRTEDIKTN
                     DEIEELAYSINIMSEKLEKAHNELNKRNENLKTFISDASHEMKTPIALIKAYAIGMKD
                     GLDDGTYTDTIIEQAENMTNTINSLLYWAKYEKKERSLCLVDLKERLYKSLKNYELLI
                     ERGSISVKCSVDDKELIISSDEDSIDMVFNNLISNAIKYTNNNEIEINLFEENERIIL
                     SIKNGIDYNMGDDIENMWKPFYVLEKSRSKELSGTGLGLTIVRTILEENNFRYRVEIC
                     DGIIEFYIIFIKVI"
     gene            complement(3661..4308)
                     /locus_tag="KRQ43_002070"
     CDS             complement(3661..4308)
                     /locus_tag="KRQ43_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742426.1"
                     /translation="MNILIADDEISMLKILCAYFKKENFNVFTAKNGEEALDIFYENK
                     IDLAILDWMMPIIDGIEVCKEIKENSNTRVLMLTAKSQSEDEIEALNIGADEYIKKPF
                     DPRVLIIRAKKLINYKNTINIKDLKIDFGSSKVFKGDKELLLTKKELELIRCLINNKG
                     MVLSREKLLDLVWGLDYEGDFRTVDTHIRRLRVKIGEDIIKTYRGLGYSLEDFND"
     gene            complement(4759..5598)
                     /locus_tag="KRQ43_002071"
     CDS             complement(4759..5598)
                     /locus_tag="KRQ43_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH2742427.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(5622..6380)
                     /locus_tag="KRQ43_002072"
     CDS             complement(5622..6380)
                     /locus_tag="KRQ43_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2742428.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNENVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(6427..6900)
                     /locus_tag="KRQ43_002073"
     CDS             complement(6427..6900)
                     /locus_tag="KRQ43_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742429.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDEHLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(6929..7345)
                     /locus_tag="KRQ43_002074"
     CDS             complement(6929..7345)
                     /locus_tag="KRQ43_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2742430.1"
                     /translation="MIHMTGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRRLEDRIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(7392..8444)
                     /locus_tag="KRQ43_002075"
     CDS             complement(7392..8444)
                     /locus_tag="KRQ43_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH2742431.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGTIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPMTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            8840..9520
                     /locus_tag="KRQ43_002076"
     CDS             8840..9520
                     /locus_tag="KRQ43_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH2742432.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(9653..9973)
                     /gene="sugE"
                     /locus_tag="KRQ43_002077"
     CDS             complement(9653..9973)
                     /gene="sugE"
                     /locus_tag="KRQ43_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBH2742433.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            10355..11182
                     /locus_tag="KRQ43_002078"
     CDS             10355..11182
                     /locus_tag="KRQ43_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH2742434.1"
                     /translation="MNFYKIAVCQMMTTENKIENINHAVDMVTEAAINGAKIIVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEYGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGVEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            12003..12677
                     /locus_tag="KRQ43_002079"
     CDS             12003..12677
                     /locus_tag="KRQ43_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742435.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDSLKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            12665..13825
                     /locus_tag="KRQ43_002080"
     CDS             12665..13825
                     /locus_tag="KRQ43_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH2742436.1"
                     /translation="MDKISNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNINMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNPHFGMGLHISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            14042..14569
                     /locus_tag="KRQ43_002081"
     CDS             14042..14569
                     /locus_tag="KRQ43_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBH2742437.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            14855..15523
                     /locus_tag="KRQ43_002082"
     CDS             14855..15523
                     /locus_tag="KRQ43_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742438.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLKINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            15526..17994
                     /locus_tag="KRQ43_002083"
     CDS             15526..17994
                     /locus_tag="KRQ43_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742439.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSFISALPSAIYASRVSPKIAMAGSTTKIKRKIKREKAIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIDKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYNSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNISLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(18234..19658)
                     /locus_tag="KRQ43_002084"
     CDS             complement(18234..19658)
                     /locus_tag="KRQ43_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2742440.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNITLLSQSNEEGLKRTIRGDDMPYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANSRGR
                     FVFAVIIMALFSPFIYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMKGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(19677..20369)
                     /locus_tag="KRQ43_002085"
     CDS             complement(19677..20369)
                     /locus_tag="KRQ43_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742441.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(20424..21200)
                     /locus_tag="KRQ43_002086"
     CDS             complement(20424..21200)
                     /locus_tag="KRQ43_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH2742442.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            complement(21197..21967)
                     /locus_tag="KRQ43_002087"
     CDS             complement(21197..21967)
                     /locus_tag="KRQ43_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH2742443.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQSLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(21964..22668)
                     /locus_tag="KRQ43_002088"
     CDS             complement(21964..22668)
                     /locus_tag="KRQ43_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH2742444.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTDGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(22923..23435)
                     /locus_tag="KRQ43_002089"
     CDS             complement(22923..23435)
                     /locus_tag="KRQ43_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742445.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEETYSGCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDISNYYLVANYI
                     RCLKKYKLID"
     gene            23761..24018
                     /locus_tag="KRQ43_002090"
     CDS             23761..24018
                     /locus_tag="KRQ43_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742446.1"
                     /translation="MILNRTELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FSNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            24161..24787
                     /locus_tag="KRQ43_002091"
     CDS             24161..24787
                     /locus_tag="KRQ43_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HBH2742447.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDNRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIEVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(25037..25816)
                     /locus_tag="KRQ43_002092"
     CDS             complement(25037..25816)
                     /locus_tag="KRQ43_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH2742448.1"
                     /translation="MNSKIYYFSGTGNSLVVSKILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIIKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPSDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(25884..26345)
                     /locus_tag="KRQ43_002093"
     CDS             complement(25884..26345)
                     /locus_tag="KRQ43_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2742449.1"
                     /translation="MGGAGDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(26321..26998)
                     /locus_tag="KRQ43_002094"
     CDS             complement(26321..26998)
                     /locus_tag="KRQ43_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH2742450.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            27231..27617
                     /locus_tag="KRQ43_002095"
     CDS             27231..27617
                     /locus_tag="KRQ43_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH2742451.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            27620..29419
                     /locus_tag="KRQ43_002096"
     CDS             27620..29419
                     /locus_tag="KRQ43_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HBH2742452.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVIILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSIIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLKQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(29774..31648)
                     /locus_tag="KRQ43_002097"
     CDS             complement(29774..31648)
                     /locus_tag="KRQ43_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH2742453.1"
                     /translation="MNKYNKIANELIEIIGENNIISITHCATRLRVMVKDREIINDKK
                     VEKVNEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEVEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIGLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(31653..33317)
                     /locus_tag="KRQ43_002098"
     CDS             complement(31653..33317)
                     /locus_tag="KRQ43_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBH2742454.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDATPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSKYSDCLIYGSIEPIDIESDNVIAYRRQLDLVVIDCY
                     YNFSDKLVEIKTEEKYDIVFQNLDDINLLNKTVSLKPFQAVLLKVR"
     gene            complement(33331..34152)
                     /locus_tag="KRQ43_002099"
     CDS             complement(33331..34152)
                     /locus_tag="KRQ43_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH2742455.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSIGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDVHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(34251..35015)
                     /locus_tag="KRQ43_002100"
     CDS             complement(34251..35015)
                     /locus_tag="KRQ43_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH2742456.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVVKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDTSTIIDFAKEMRMKGTYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(35012..35761)
                     /locus_tag="KRQ43_002101"
     CDS             complement(35012..35761)
                     /locus_tag="KRQ43_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH2742457.1"
                     /translation="MRLESLVNQSYNSLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKSGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(36265..36870)
                     /locus_tag="KRQ43_002102"
     CDS             complement(36265..36870)
                     /locus_tag="KRQ43_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2742458.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMKIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            37049..37147
                     /locus_tag="KRQ43_002103"
     CDS             37049..37147
                     /locus_tag="KRQ43_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBH2742459.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFD"
BASE COUNT        12901 a         6185 c         4363 g        13716 t
ORIGIN      
        1 tagcatgtaa tgctgttgct gctgttactg catcttgtaa tgctgtttta tctactgcta
       61 ctacttttcc tgctttaaat gtgtctgttg ctgtgtttaa tgctgttact gcatcattta
      121 cttctttttg tgttacacca gatttgtcta atattgcctg tgctttgtct attgctgttt
      181 tatatattgc ttttgaccct actttatatt cacctacatt tgttccctct attgcttcat
      241 tatacaattt atttgctgct gttattgtat ttttcaaaac tactttatct acttttgatg
      301 aagaacttcc tcctccatgt gaagaacctc cacttgatga acttcctcct gaagagttag
      361 aacttggact atttccactt attgttggag aattatctcc cttaacacta cttattgtac
      421 ctttattatc tatagtagtt cctttagaat tatttgtaac tgtagttatc ttaccaccat
      481 tagtcacttt tacttgactt gctccagatg ctactgttaa actaccaatc tcacctttag
      541 aattattttc tatcttggct ccatttttat cattaacctt taagttagtt atttttccgt
      601 agttaacaaa agttccatct tttacatcat ctataactac atcatccact tttgcatagt
      661 tatttacatc accattaggc atgttgatag tcacagtctt tgtatatgta ccatttaagt
      721 ttactgttat cgccttatca gtttgtattg taaatgcttc tttaacctca ctagttggct
      781 taaagtttat aacatcatta gcagtagctt tatctatagc tgattttaat tcagaaattg
      841 ttttagcttc aactgttttt acttcttgta atgacttcat ttcattaaat gctgtctcat
      901 taccattccc accaacttta gttatcttat caaaactctt agagttaact agagattttt
      961 gtgaagctga taagttcttt ccaactaaaa ctactggtga ttgattttta gcacctaata
     1021 cacctactgc tagtgcatct ataagttggt cttgtttatt cataccatct ttagttacat
     1081 aagcattttt taaatctgtc tttttataaa attcttttat tacttttgca tttgtatcat
     1141 ttctatctgt tccacctagt cttgtactat ttggtagttt atttttaaca gcttcagaaa
     1201 ttgaactctc tccacctact acataagatt gagttattcc agcatctttt ataaatttgt
     1261 ctgcaactgc tgttccattt ttagaatcag caagtattac tggcatattg ttttgtgcag
     1321 ctggtgctcc tacacttaca gcatctgcaa gtcctttttc accattaact acagctattt
     1381 tcttaacatc acttatagca tctaatttct ttgctaattc taaggatgtt tgatatctct
     1441 cagctccaga gattctctca aaagatattt ttaaatcttt tatttctttt tctatatttg
     1501 tacttaatac agaagttcca cctattaagt atactttttt agcttttaat ctttgtattt
     1561 ctgctttcgt cttatcattt aatttatctt tacttgttaa aagtattgga gcattttttg
     1621 cttttgcaaa tggtgttgca gatagagcat ctgctataga tgagtcgttt acgattacta
     1681 cctcatcagc atttttccat ccatcttgac ttattttaac agcagtttca tatctttctt
     1741 gccctgttaa atttgttgcc acagtttgtg cactagctat gcctgctgtt gaacttccag
     1801 ctatcattgt aactgtaagc attgcagcaa tcttctttgg tattttcatt ttattttctt
     1861 cccccttgtc catttgatat tacttaattt tttaactttg ttcccgttct aattctaaag
     1921 gatacttaat atctaatttt aaagaggttt ctaactataa tgatttcata attaatttgt
     1981 aattattttg ttacattaca gtcattatgt aaggaataga gaaattttct tattgattga
     2041 aaaatttgta aatttatatt ttaaggtaag tttgattttt atgttaatga attgttataa
     2101 aaaacatggt tttgtataaa aaaagtagcc tttagaatta aaagtgctac tctttttaca
     2161 aataaatttt attatttata cttgtaatta tatattaaat aaccaatttt atccatatga
     2221 aaaacaaata attgcgatat ttttttaatt attctttata tttacatttt aattcaaatt
     2281 acttttataa agataatata aaattctata attccatcgc aaatttcaac cctgtatcta
     2341 aaattatttt cttcaagtat agttctaact atggtaagac caagaccagt accagaaagc
     2401 tccttacttc tcgacttctc taaaacataa aaaggcttcc acatattttc tatatcatct
     2461 cccatattgt aatctatacc attttttatg gataatataa ttctctcatt ctcttcaaaa
     2521 agattaatct ctatttcatt attattagta tactttatag cattactaat caaattatta
     2581 aataccatat ctatactatc ttcatccgaa cttattataa gttctttatc atctacactg
     2641 catttaacac ttatactacc tctttctatc aacagctcat agttttttaa acttttatat
     2701 aacctttcct ttaaatctac cagacacaga cttctctcct tcttctcata ttttgcccaa
     2761 tataaaagag aatttattgt attggtcata ttttctgctt gttcaattat tgtatctgta
     2821 taagtcccat catccaaacc atctttcata cctattgcat atgcttttat aagtgctatt
     2881 ggagttttca tttcatgaga tgcatctgat ataaaagttt ttagattctc atttctttta
     2941 ttcaattcat tatgtgcttt ttcaagtttt tcgctcatta tgtttatgct gtaagctagc
     3001 tcttctattt catcgttcgt ttttatatct tcagtcctaa aatttaattc agatatatct
     3061 ttagataaaa actttaacct ttccataggt tttataactc tgtttgataa tataaatgta
     3121 agtatagtta ttataactac tgaaaaaatt cccattatta tattaaatct atttacaatg
     3181 ccaatagttt cttcagaatg ttctataggt atagatatag caaacaaata attatccttc
     3241 ttgataaatt ttacaagcaa actatatttt gttttacctt gattgtatat cttatttata
     3301 cttttcttat caatattatt taaactattt tcttcaatcc aaaacttatt taaacttaaa
     3361 ccttttttcc aaaatgcatt taataaatct tgatttattt tatctatatt acctttatct
     3421 ttatgatttt tatctaattc tatatatacg atatctatat tatttttttc ttcaattaaa
     3481 gtaatgtctg attttaattt atctatgtct ttatctttaa tttcattttc aacattatcc
     3541 aatatatttc ttttttcatg taaataatat ctatgaataa acatactatt tataattata
     3601 gatattatat aaacaactac aactactata gatatactta tggacaattt tttgtttagt
     3661 ttagtcatta aaatcctcca gactataccc taatcctcta taagttttta ttatatcttc
     3721 tcctattttt acccttaatc ttcttatatg agtatctact gttctaaaat ctccctcata
     3781 atccaatccc catactaaat ctaaaagttt ttccctagat aaaaccattc ctttattatt
     3841 gattaaacaa cgaattaatt ctaattcttt cttagtcaat aataattcct tatcaccttt
     3901 aaaaacttta cttgacccaa aatctatttt taaatcttta atattaattg tatttttata
     3961 atttattagt ttcttagctc ttattattaa aactctagga tcaaatggtt tttttatata
     4021 ttcatctgct ccaatgttga gtgcttctat ttcatcttca ctttgacttt tggcagtcaa
     4081 cataagtacc cttgtattac tattttcctt tatctcttta caaacctcta ttccatcaat
     4141 tattggcatc atccagtcta atatagctaa gtctatctta ttttcataaa aaatatctaa
     4201 agcctcttcc ccattttttg cagtaaacac attgaagttt tcttttttaa aatatgcaca
     4261 aagtatctta agcatactaa tttcatcatc agcaattaat atgttcattt attcacatcc
     4321 ctaaaattca ttattatatt tcatattata tccattactt taattatata aaatatatgt
     4381 tacaggaagt ttacaactat ttataataca ttagttatat attataatat ctcgacaatg
     4441 tcttaacaat atctcgatta tatattttaa tatgtaacta atatattata atattttaat
     4501 taaattaaat aaatttatat ttttttgaaa ttacttaata ttttatatgc aaatgaaaaa
     4561 gcacctcatt ctgattaaaa atctttctga gatacttttt aaaatattaa atactatata
     4621 tagcttatat aagtttaaaa tttaatctat tataaaatta ccctaattgc taaacttttt
     4681 aatataaatt ttccaacatc ttacaaatat aatcaataga tatagaatcc taatttacac
     4741 accaacatat atatttattt aaaatagtcc caaaatacct gtaatagctc ccactactat
     4801 cagtataaac attattttta ttggagaaag gccttttttt aaagcaaaga gtactaataa
     4861 agtaagtacc aaaggaatta atcctggaaa tatcttatca agtaaatccg tttgaagact
     4921 aaatttaaaa tcaccactag tataacttat tggtgtagat aaattaataa acctacctac
     4981 aagtcccccc atgactaaag tacctaatat agaagcccct tctataacct tatttactat
     5041 tccaccttga agtatacttt caacagcttt tttcccatac ttatatccat ttgtccacat
     5101 tccaaaagaa attgaagtca ttattatata ttgagctatt acaaataata taggacctgc
     5161 aattgatgct cctccctcag ttaaaccaat acaaacagct aacactatag gagttataac
     5221 tccttgagtt aaagtatcac caattcctgc tagtggaccc atcaagcctg ttttgatagc
     5281 attcatacca tctccactta tttcatctgc tccattagct ttttcttctt ccatagctat
     5341 tgttattcca tgtataacac atccacatat aggttctgtg ttaaaaaatg ctaaatgagt
     5401 ctccacttct tgttttaact cttccttatc tggatataat tttttaagta ctggcaacat
     5461 tgaatgtgag aaagctgttg attgcaatct ttcataattg taattagatt gcgcaaagaa
     5521 aaaccatctt aaccatgatt ttattacatc ttttttgctt aacgttttct tagatacttc
     5581 attttttata tctgacataa tattttcccc ctcacatgta tttaagatgt agcactatct
     5641 tttccgtact taattgaagt aattgtaaga gcaagtatta ctccaataac agatattact
     5701 attatatcta ctttaaaata aacagccatt agtattccta atatgaaaaa gggcatagta
     5761 aacttgtttc caatcaattt taaattcata gcaatcccaa gtgctggcaa catagcccca
     5821 attacattaa atacatgtaa cacattctca ttcattactt ccaacatacc atctatcgca
     5881 tttggaccaa aataaacaac taataatgct ggtataaaac tcattgcaaa taacagtatc
     5941 tgtggtggta ctatatttat aaatgctact ctatcaacat tccctttttg aacctctcta
     6001 tcagcccaat gtgcaaaaaa agaatttact gtcatttttc caatccaaag tacagttgca
     6061 acagttccca atggtacagc tattgccatt gcagtactta catctagctt agatgctata
     6121 gctaaagcag tacctacata tcctgcaaaa gctgggtccc ccatctgagc tccccctgct
     6181 gatataaaac ctagatatat catatttata cctgctccta taattgctcc ttgaacaggg
     6241 tctcctaata taattcccgt tacaaatcca gccaatagag gtctattcca tgtaaaaaat
     6301 ccaacatagg tcaaccacgg actccaagaa agataataaa aaattgctat taatactgct
     6361 tgaattagtg aaatgtgcat attcttcctc cctattttct tttaaagatt tacaagatag
     6421 tcttttttat aataatgttc ctacatcaat tttctttgca tctggtacta tttgtataaa
     6481 gcatttaaca tcttttgata ttagttctct aaatatttct ttttcttcat ctgacacaga
     6541 tatattttta taaaaacttt ttctaccaag ccctgctccc atacctccaa cattcaattc
     6601 ctttaaatct accccactat ttactaaacc taagacagtt ttagggtatt tgaccaatac
     6661 tattaaatgt tcatctccat tatgtgattt taaaacttca gcacctgatt ctacatcatg
     6721 tacttcaacc ttaacagttg atggagctgc catttgtaaa acttgaacta taaatgggtc
     6781 ctttactact aaatcatcca cgattactat cctttttgcc gatgtaatct tacaccaagc
     6841 agtaataact tgcccatgta ttaatctatc atcaattctt gttaatgcta tattactcat
     6901 aattattcct ccagattttt aatttatttt acaactttaa aacagtttta acatctttga
     6961 ttcctgatat cccaacttcc tcacataaat tcttcaagtc ttttaacttc atagtatctc
     7021 tgtttaaaaa tagctctaaa agcataggta aatttacacc tgtcaaacat tctaactcac
     7081 ataccttagc aaatttattt attataatag cagatgtatt aaatggagtc ccgccataaa
     7141 aatcaagcaa tactaaaacc ccttcatcct tatatttctc aattctatct tctaaccttc
     7201 tactaaactc atctatgctg tcaccatggt ttaatcctaa agtttctaca ttttcctgtt
     7261 tgcctactat taattcagca ctttctaaca ttgctttagc catatttcca tgtgtggcta
     7321 taattatccc tgtcatatga atcatacctt tcttaacctt gtttatatgg attattattt
     7381 agtactctaa tctaattatc tatattaatc attatcttac caaagaaaat atcccttttg
     7441 tatacttttt caaaataagc tggtacttct tctaaattta ttctatgtgt tactaatttt
     7501 tcaacattca tatcaccctt ttgcatatga tacaatccag cactccattc ttttcctggg
     7561 aatggaaaag agtttccaaa ccaagttccc ttgacagtta attcacttct tactatcttt
     7621 tcaaattgtt ctctagtcaa agctacatcc ccatatggta cacctgcata caatactgtc
     7681 cctccctttt tagctaacaa caatacttgc ccacatgtca ttggagtccc agccgattca
     7741 ataacaatat ctgcaccatc tccatcagtt aaccttttta tttcttctac aatattcttt
     7801 tcttttgcat ttatacaaat atctgcccct aactctttcg ccaagtctaa cttctcatca
     7861 aatacatcta cagctattat ttttgtagag ccaaatatct ttgcccattg tattgaaaat
     7921 aatcctattg tacctgtacc aagtactaca acagtatctc caactttagc ttctgatcta
     7981 aaaagaccat gccctgctat acatactggt tctagcgcag cggcagtctc ataacttatc
     8041 tcatctggta tttttattaa attcctctct ttcacctttg tatactctgc aaaacaacct
     8101 ccaagttctt tatttcctat tattgctaca ttattacatc ttgaatacaa tcctttttta
     8161 cattcatcac attcaaaaca tggcatagct ggacaaacag caactctatc tcctatttta
     8221 aaactcctta cttctttacc aacctgtgcc acttctccag aaaattcatg ccctaaaatt
     8281 tctccaacca tatgtggacc tgtctttgaa tattttgata tatcagaacc acatattcca
     8341 gctactttta ctttaattat tacatcatct ttttctaata tttttggtac atccacatcc
     8401 tccactcttg tgtctcttat accatagaat ctaactgact tcactattaa ccacccctac
     8461 tttttatttg agaatatatc cctattgttt atatgttaaa tatctaaagc aactttcatg
     8521 ccaatatatg taagcattgc attcatgcat tttataaaat tatcattaaa tgtgtgtcaa
     8581 agtgtgtcaa aagtttctta tattaaaact tatgtgtgtc aatataaacg acactaacat
     8641 tttatattag ttctcttatt ataagtttta taaaatgtac tttttttgtt atttttataa
     8701 aattgttcgg aaatttccct tctatttgtg atataatatt aaatataagg tatcaatata
     8761 aattttcatg cgaatatcag aacttttttg acactaatgc cttattcaat ataataattt
     8821 aactttttgg aggttgttta tgaaaaaagt gtatcaagga aagactaaag atgtttttga
     8881 attagataat ggaaattact tacttaaatt taaagacgat gtaactggta aagatggagt
     8941 atttgaccca ggcgaaaata gtgtaggtct aagtatagat ggaattggta gagctaattt
     9001 agagacatct gttaagttct ttgaaattct aaacaatgct ggaattaaaa ctcattatgt
     9061 aagtgctaat ttagaagaag caactatgga agttctacca gcaaaagttt ttggtaatgg
     9121 attagaagtt atttgtcgtt atagagctgt tggtagtttc ttacgtcgtt atggttcatg
     9181 tgttgaagaa ggtgctaaac tagattgcta tgtagaagca actttaaaag atgatgaccg
     9241 ttgtgaccct cttataacat ctgaaggttt agaagcttta aacattatga ctcaagctca
     9301 atttgattca atgaaaagca tgactcaaaa aatttctaat atagttcgtg atactatagc
     9361 tgaaaaaggt cttgaacttt atgatatcaa atttgaattt ggattctaca atgatgaagt
     9421 aatcttaata gatgaaatag catctggaaa tatgcgtgtt tataaagatg gtgtaatagt
     9481 tgaccctatg gatttaactg ctcttttatt agataaatag tatatacata taattttcaa
     9541 atataataaa cttataaata agataagcta tgaagtaaag actttttaaa tgttgattat
     9601 ttttaaacat tttctcgcct ttaatttcat agcttattta aattaatata ctctaattag
     9661 tagataatag ctttaaccct acaattccca ccacaataaa gcctatacat gcaattcttg
     9721 atatactaat aggctcattt aagatagcca tgcctacaat agctgtaccg acggtaccaa
     9781 ttccagtcca tattgcatat gaagttccaa gtggaagatg ttttagtgct aatgacaaaa
     9841 aataaaaact tacaatcatt ccaacaacag taagtatact tggagttaat ttagaaaatc
     9901 catgtgaatt ttttagttga aaagcccaaa acacttcaaa caaacctgca acaaacaaaa
     9961 ataaccattt cataaactca tccctctttt caaatgtatc tcttattttt ccaataaaat
    10021 aacctgagaa atattataaa atatctccca ggtttttgtc cttccgtgtt cacaacaaaa
    10081 actatgttgt gggttttatc tcggaccagg ccaatcatta ataattgcaa aaccctataa
    10141 aactctatta attattctat tttatctata ataatactat caacatatat aaaaaaagtc
    10201 aatatatggg ttccatctat aataaaaata acttttatat accttttaat attcttattc
    10261 acttctctcc atacccattt aggtcaatct aagaatatct aatttttatt taatatgtta
    10321 taataacata aaaatattga aaggagtaat ttctatgaat ttctataaaa ttgcagtatg
    10381 tcagatgatg accacagaaa ataaaattga aaatatcaat catgctgtag atatggtaac
    10441 agaagctgcc atcaatggag ctaaaattat agttttgcca gaaatgttta actgcccata
    10501 tgaaaataaa tattttccta aatttgctga agaatatcca ggtgaaacaa caacgatatt
    10561 gagtaaatta gctgagaaac atggaattta tctagtttct ggtagtattc ctgagttaga
    10621 atatggaaaa atctataata cttgctatgt atttgataaa aatggagctc taattggaaa
    10681 acatcgtaaa atgcacttat ttgacattga agttacagga aaagttagtt ttaaagaatc
    10741 agatactctt acagctggaa atgatgtcac tgtaatagat accgaatatg gaaaagttgg
    10801 tatagctatt tgctatgata ttcgtttccc tgagttatca cgtttaatgg ctcttaaagg
    10861 tgttgaaatc gttatcttac ctgctgcatt taatatgact actggtcccg cccattggga
    10921 gttatctata agaatgcgtg ctttagataa tcagatattc tatgttggtg ctgcacctgc
    10981 tagaaatatg aatgcttctt atatagcttt tggaaattca agaatttcag acccttgggg
    11041 aagaataatt gctcaagctg atgaaaaaga atgtattatt tatgctgaca ttgatagaga
    11101 tttaattcct gacataagac aacagttacc acttcttaag cacagaagaa ctgatttata
    11161 tgaacttaat actttgaaat aaaacagaac ataaccccat aaatcataaa ttaagtgtta
    11221 aaaaaattta tggggttctc attaatttga tttaaaatta atttaataaa aataatgcta
    11281 aaattaattt aattaaataa tactaataat tactaatgat tatgctaatt gtcagcattt
    11341 actaatttaa tcactattag ttatttcttt tattaaatat ctttactttt tttacttatt
    11401 atgtcttcta gctttacatg tggattatgg tatttctttc tatttttagt cacatctttc
    11461 tattgaattg cttgcttaaa acaccaatgc acacatgcca gataatgttc acaattatgt
    11521 aaaaatattg ctctaccttc ttcaatgttg atattatctc tcctagttaa tattatcttt
    11581 cctaaaattt cttttaatta aaaaacaaca ttagttgata tatcaagtat attttaagca
    11641 actgaaaaaa taataataat tgatatatca actaattaat gtagattaat tcatttttat
    11701 aatttatata ctttttaatt aatctacctt tttaattaaa atccttcctt tctatttatc
    11761 cattttcaac ttaaattata agatttcatc agctgtgttt ttgcattcca ataaatatta
    11821 aatatcaaat atatattcta ttaaaatttc taataatttc atccttgatt tatttaatat
    11881 ataaaaatat actaacttta atgattaagt tttgaaatat aactaagaat ttgagaattt
    11941 attgagattt ttatactaaa atataaatac tatacaaact taatttagaa gggagcattc
    12001 ttatgaacaa taaaatactc gtcgtagatg atgaggaagg tataataaca ctcttaaaag
    12061 attactttga aatgaatggt tatgaggttt acactgctca aagtggaaaa gactcattaa
    12121 aaaaaatatc caaaaatcca gatatcattc tacttgatat aaacatgcct gaaatagatg
    12181 gaattgaagt ttgtaataga attagagatt atgtatcatg ccctattcta tttcttacag
    12241 ccagaattga aaatactgac aagataaatg gttttcgtgc tggtgctgat gattatattg
    12301 taaaaccttt tgatttagac gaacttggag ctagagtatc tgcacattta agacgtgaac
    12361 aaaggaagtc aaatcaaact aaaattaaat tttataatga tttaacaata gattacgaaa
    12421 aaaggttaat ttgtatatat aataatcaga tttcactttc aaaaaaggaa tttgatatag
    12481 tagagcttct ctctatgaat cctggacagg tatttgataa agaaaaaata tatgatagag
    12541 tctggggata caatagcaat ggaaatagtg atgttataat ggaacacatt agaaaaatac
    12601 gaatcaaact atcaaaacat actcttgaaa attatataga aacagtctgg ggagttggtt
    12661 ataaatggat aaaataagta atatgtcatt aaaaaaagct ttctttgttc ttactttatc
    12721 ttcactaatt atagcatcag tacttactac tttcgcatac attttactta ataatctata
    12781 taattctata caagataagt atttaaaaac acctataaat acaggtatta taaccatagt
    12841 tcaaaacaat gtgaaccaat ttagtgatta tgataaaaca ttacttaata taatcaacat
    12901 acttcagctt gtacttccac ttatattttt tataggactt ttattattag ctgatataat
    12961 tttttacaag gtaaaattaa aaacacccat agaaatcctc aataaaggtg caatggaaat
    13021 atccaacaac aatttagatt tttgcttaga atataataat aatgatgaat taggtaatct
    13081 atgtaatgct tttgaaaaaa tgaggtctga actaaataaa aacaacataa atatgtggac
    13141 tatgattaat gatagaaaac aacttaatgc tgctttttct catgatttaa gaaatcccct
    13201 aacagttcta aaaggttact caaactattt aacaaaatac ataccaacag gcaaacttag
    13261 tgatgagaag attttatcaa ccacacaact tatgtctgag catattaaca gaattgaata
    13321 ctatgtagaa aatatgagta atgctcaacg attagaagat ttagttgttt caaaatctat
    13381 gtcgaatata aacaagttta tagaaaactt agatgaaaat atatctatca ttgctaaaca
    13441 agaaggaaaa tcttttacac ttaaaagtca aataaataat ataaatctat tttttgatga
    13501 aaatatcatt cttagagtcg tcgaaaatat aatatcgaat gcttttagat atgctagaaa
    13561 taatgtatcc atacttatat atcttgaaca agaactcctt acctttgtaa ttgaagatga
    13621 tggtatagga tttagtaagg aatctctaaa attagcttta agacctttct atagagataa
    13681 gactttaaat gacagcaatc cacactttgg tatgggtctt catatctcaa aaatattatg
    13741 tgaaaaacat ggtggctcta tttctattga aaataattct actaacagtg ctaaaattac
    13801 tgctaaattc tcaacaagaa attaaaatga ttttgtaagc tttcattgtt cttatataag
    13861 ctttgttagt ttagaattta taaaatgtat ttcaatttac aaccaatata tatactattt
    13921 tgtagaagtt gtaagagttg cttcaattat aatattttgg caaaaggcat ttgaaacaat
    13981 aatagaaata tatatttaaa tatgtagaat agtatgaaac tagaattttg gaggtgatta
    14041 tattaaaagt tttgctaata atattacatt ctctcgtatt gtgtttgcat tgctaatgct
    14101 tagttctaca ttctgttcac tgcctttctg gatatgttat ttttggtgtg gaattagtga
    14161 tatacttgat ggtcttattg cccgaaagtt gagacaacaa agtggaatag gtgcaaagtt
    14221 agatagtatt gctgatttca tttttgcggt tacaattttg gttactgtcg gaaaaaatat
    14281 tgctcttccc atgtatctat ggtggtgtat tgttgcaata gcattattac ggttgattag
    14341 ttacagtatt ggttttttta agtatcgcac attttcatcg cttcatactt tgatgaataa
    14401 aatcactgga atttctatct ttgcttttcc attactctat atttgctttg gtcttgatgt
    14461 tgcaggaatt atgatatgta tcgtggcttt tctttcttct tttgaagaaa tagcaattat
    14521 gataaaatca aaagaattaa atcgtgatat aaaaagtata tttatgtgac aacttagaat
    14581 ttgtgacaaa aataatttat ataataatga ggaagtaaaa cataaaaaat tatccacaag
    14641 tttatgtgta aaatagtttt aaagcaatag agttgtattg taaagccttt agtgcataaa
    14701 ttacatttta aattaaaaat gatactgaaa ctgcttatca gcactgcgaa ttatccgtaa
    14761 atagtgaaga ctttttagat ttaagctaaa agttgggaaa aaattgagtt ttaaaactta
    14821 cactcttctt atatagaaaa ggagagtgtt ttttatgatt ataaaagcaa aacaattatc
    14881 aaaaatatat ggttctaata acaataaagt tatagcactt aataatgtaa atttaaaaat
    14941 aaactcaggt gaatttgttt ctgtaattgg accttctgga agtggaaaaa gcacactttt
    15001 acatatttta agtggattag ataatcctac ctctggacaa gtgttacttg atgataaaga
    15061 tatatataaa cacactgaaa aagaactatc tgcacttaga agaaaatcct ttggattcgt
    15121 ctttcaacaa tttaatcttt tacctgttct tacagcatct gaaaatattt caatgcctgt
    15181 acttctagat aaaaaacaac ctgataaaga ctatttaaat gaaatttcat cattacttgg
    15241 aattgcagat agactcaatc atcttcccca tgaactttca ggcggtcagc aacaaagagt
    15301 tgcaatcgct agagcactta ttgcaaaacc agatataata tttgctgatg agcctacagg
    15361 aaacttggac agtaaaagtg gcagtgaagt tatgaatctt cttataaaaa cttcaaaaca
    15421 gtttggaaag actttagtgg taattactca tgatgataga attgcaaaac ttgctgatag
    15481 aaaaatttca attattgatg gtgttcttat ggaggtgaaa tagaaatgaa gaattacctt
    15541 tcactttcaa taaaagaatt aaaaagccag aaacttatga ctacattcat cattatagca
    15601 atagtactat caactattat gacaactgtg gttggacagt caattggtat cctacaaaat
    15661 ttaagaattg aacaagcccg ttcttttaat ggtgatagac atgtatcctt tcaccaactt
    15721 actaaaaatc aagttgatga cataaagaaa gatgatagag tttatcaagc tggtacttca
    15781 ataactattg gcagtagtaa aataaaggat tctggtatct ctgtacttgt aaaagagtat
    15841 gataaaacag gactttctaa ctacccaaaa ttaatgaaat taaaatctgg acatttgcct
    15901 aaagataaaa acgaaatagc cttagatgaa aacactctaa agcttatggg tataaaacca
    15961 agactaggag tgactatacc tatgaattta gatatttcac ttttaaatga taccatacca
    16021 ccatataatt acacagctaa ctttaaattg agtggcattt tagaggatga ttatacagga
    16081 tatgtaagtg gtatagtaaa tggtattgta ggtaaaggta catcagaaaa tctattacct
    16141 aagagatata ttttatcctc tttggatttt aaaataaaac agcaagaaaa gtttcaagaa
    16201 atagtaaatc aattagctaa aaaaataaat ctttctcaca attcaattca atataattgg
    16261 atttacttaa atgctcttaa gatacagttt gaaaaagatg aaaatagttc taatagtgat
    16321 ggtatatcta tgattatatt ggtatcttta tttgttgcct tattggtttt actggcttct
    16381 ggacttgtaa tctataatat tttaaaaatc tctgttacaa agaaaattaa agagtatgga
    16441 tgtttaagag caataggagc tgaaccaaac cagatatata agatagttat tttacaaatc
    16501 ttaattttat gtactgttgc catacctatt ggagctgtaa ttggaattat ctcttctaaa
    16561 ggcataactg gaatggtcac taatatctta aatccagata tacttctagc aaatgataat
    16621 aaagaaatta ctgagcttat acataaaaat acaacagcat atatgttccc attagtatta
    16681 agcactaatg tatctttgat tttttcattt atttcagcat taccatcagc aatatatgct
    16741 tcacgtgtct ctcccaaaat tgctatggct ggtagtacta ccaaaatcaa aagaaaaatt
    16801 aaaagagaaa aagcaataaa aaactttgaa agacatctag catggctaaa cttaaaaaga
    16861 aataaaggaa gaactataat aactatacta tcattattta tgagtataac agtattcgtt
    16921 gcattgagtg agttctctaa tgtattagat gtatctaggt cagtaagcaa tttaaaagaa
    16981 ggagattttt ccttaacaaa tgaaatatct ggttttgata aatcaacact agataaaata
    17041 gataaaatga aaaacgtcaa tcgcacttcc tttataaagt actctgaata caaacagggt
    17101 gaaatagata cagatataaa ttttgaaaat agtggtgaga tgttaaaaat cattggaatt
    17161 gacgagcaga ctttaaaaga cttaatgcct tctattacag attctatact agaagacttt
    17221 aaaaatggtt ctatctgttt tataaaaaat ccgattgcta tttctacacc aggtgtaaaa
    17281 actagacata caaatttaaa acctaaagat agtatcacaa tcaacaaaaa acaactagat
    17341 atatatagta cagtagataa aatgttcttt ttacaaggta atggctggat aaatggtgtt
    17401 gatgttattg tatataattc tgtttataac accttgacaa ataaaaacaa gttcaaccag
    17461 ataaatattt atgctaaaga taaatcaaaa ttagaacaaa taagattgtc tattgaacag
    17521 atttgtgaaa ataatcctgg ctctcattgg atatcatata ttgaatcaga taagcaactt
    17581 aaagagagtt ttaaacaaat agaatttcta gcatgggcag ttatattatt tgtgggattg
    17641 attggtactt taaacatcat taacacaact catacaaata taaatactag gactaatgag
    17701 attggagtta aaagagctat tggtatgagt aatattagct tatataaaat gtttttatgg
    17761 gaaggtgttt attatggaat ttttgctgct atatttggtt caattgctgg gtatgccagt
    17821 gctattatta taaacatggc aactatagaa aagcttgatt tcactaatat accaattact
    17881 tcaattttac aagctactat tatttctgta cttgcatgta ttatagctac tcttattccg
    17941 ttaagaaaag ttaaaaagat gaatataatt gactgtatag atatcaattt ataactattt
    18001 tacagataat aatataaatt aaattatcaa tgactgtctc tattttcttt caaatctaac
    18061 taataaatct ttttaactat aatataagct ttaaaaaagg cctgtctcaa aatagagata
    18121 agcctttttt cattgtcgga ataatgaaaa tatatttaac ttcacaaaaa aagagtgcct
    18181 cacgaattaa aaatttcgct ttgagacact cccctttaat ttaaaatata tagttaaatg
    18241 ctatgccaaa atttcacaca tgctccacct gattttgaat tttctatttt aacagaacct
    18301 ccaagctgtt ccactaattg tttgacaatg taaagcccaa gaccagaatg tccacctttt
    18361 gtctgcctag cttcatctcc tcgataaaac ttatcaagag ccttttttaa atctttagag
    18421 ctaaaccctc taccagaatc acaaatctca taagaaatac aatttttttc atcctttaca
    18481 gtaatactaa tattaccacc tgatggagtg tattgcagac tgttggatat gatattatca
    18541 aaaattcgtg tcaacctatc cacgtcgatt tgaattgggg attgtatatt ccccttcatt
    18601 ttcaatataa gttcaacttc cttttgatga gcctgtaatt catagtcttg caccttttgc
    18661 ctcaaaaatt caggtaaatt tataggaaca agatttaatt gtatatttga cttttctaag
    18721 tcagacgtat attgcatctt ttggacaaga gcagcacttt tttctgtatt ttctcttatc
    18781 actgtaagat acctatgaag tttttcattg tcatctgtat tattaccaat aagtgcatct
    18841 gtatatccca aaataataga aagaggagat tttaaatcat gtgctagagc ttccaccatt
    18901 tcaacacgtt cctgctccat cttccactgc gcagataaag aaccttttaa ttcgtctttc
    18961 atttcagaaa aggcactaca aagtttaccg agttcattat ctgaataata gtcgatttca
    19021 aaatcaaggt ccttttcttt tatcttcttg gacgcatcaa tcaatagatg taatggttga
    19081 ttgatattct ttacaaagcg cttagaaagc catctagtaa aacccacgat atatataaat
    19141 ggagaaaaca gagccattat aataactgca aatacaaatc tccctctact atttgcaaag
    19201 gttattttga cttgatagaa tagaataaca gctccctcaa tctttccatt atcccctttg
    19261 attggaacag tatggatata accaccttta cgaacagttt tattgataaa attattaaat
    19321 aattcttctt ttgttttaaa tagttttttg gggttagtac catatagaat attgccatta
    19381 ttatccacaa cttgatatgg catatcatcc ccacgaatcg ttctttttaa accttcttca
    19441 ttcgattgtg ataacaaagt tatgtttttt tcattgatgt atttttcaat tctaggaact
    19501 tgtcgctcat aatagtttgg tggatagata tccttattta aggaatgaat atacaaatag
    19561 agagcaaata cataagtaat cactgtggca actatactgg ctattataat aaaaataaaa
    19621 gtatgtctaa attgggtaat aagggattga tttttcattt aataacctct ctctctttac
    19681 attttattcc acttataccc aataccccaa actgtggaaa tatattcttt ttctggtgtc
    19741 acagcagaaa acttagctcg tatttttttt actcgttcaa caacagttga ggaatcacct
    19801 tcagaatcac acccccatac tttttcatag atttgttctc ttgagaaaac ttgtcctgca
    19861 tggagtgcta gtaattcaac aatatcatac tctatttttg ttaaatcaat attcttacca
    19921 tcaattttaa ttgcacgttc cttcatatat aagcataact tcccaaaata caaagtagat
    19981 ctcttgttct cttcattgat atactgtgaa cgcttttccc tacgcagatt agcttcaatc
    20041 cttgccataa gttcacgcag tccaaatggc tttgttacat aatcatcccc tccaaaggtc
    20101 aaccctttga ttttgtcggt ttctgattgc tttgcactta aaaatataat tgggcataaa
    20161 acatcatctc taattgcctg acatacctca aatccattca ttttaggcat cataatatcc
    20221 agtataataa ggtcaggctc ctgttttgat aactctatac ctgcctgacc atcataagct
    20281 atcaacactt catgtccttt tgccttcaat tcatcctcaa gtagcattac taggtccatt
    20341 tcatcatcaa taatcaatat tttactcaat ataacaccac ctttctctta tgggaaggtc
    20401 agtattaaaa caatattcgt ctactaataa cttttccttc cctcccacat tttaaaccaa
    20461 ataacgcctc ctatcaagaa tataatcaaa cctattgcta ctactataag ctctatacta
    20521 gctgtttgca tcactttaga gtaaaatgcc tcagttgaaa tagttccagc ttctttaata
    20581 aaataaattc ctggaagcat acctagtttt actggccatg tccatggaac aaatgcccat
    20641 actttttcac caacgctagt taatccaagt attgctgcca tcaaaattcc accgatacta
    20701 ataccaatag atgcacccat accccatgca aaactcaccc aaagatgaat agctaatagt
    20761 ggaagtgtcc caatcaccac aagtcctgct gctgacagga ataaccatat tgttgctcca
    20821 gatggcactg caatactcat tcctatgcaa agtatcaacg tagcaataaa tgtgcatata
    20881 gttaggcaaa acagaagaaa aagaaatttt cccagatata atctaacacg agaaatacct
    20941 acacataaaa aaccattaaa atttccagca agctcttcct cctgcactat aaatcctgct
    21001 aaaataccta ctccaatagg aatgatgaat acagtccata ctgtaaaaaa tccttcaaaa
    21061 gcaaattctt gtgtacttcc agatttagtt gtgagataaa aaaccacaca taatgaaaaa
    21121 ataataggca tacaaagagt aagccactgg acagctgtcc tctttgctcg aagccattct
    21181 gatgataata gctttatcat ttgtcatccc tcctattgaa ccaagctgca gtaagcgctg
    21241 ttaatactat aaacacaacc aaagaaacaa caatcccaat aggaatcact gaagtattca
    21301 aaagtgggtc tccagcttct aatatagtac cgttaggatg tatgttgatg attgggcata
    21361 ccattctaac tgcccaactc caaggtactg caatccaaaa tggttttgtc gcagcaagga
    21421 caccaaatat catacctaaa gctccaactc ccatacttag gaacatacct ttccatgtag
    21481 ctagccatag ctgaagtgga agtatagcaa gagaaacaac ccagcataca atacttgccc
    21541 ctataatctg tccaaaagga actggaccag ctttcaatat taaaccagtt ataattgtta
    21601 cgactattaa aactaacgtt gaaataaaac tgtagactgc catagctata actttattaa
    21661 tccaaagtgt cataggagac acattgtgtg tacgtaaagc acgataattt ccagcttttt
    21721 tttcctggaa agctaccaaa gtagcaaaca atgcaaatcc aataggcaga aataaaaatg
    21781 accaccagtt aaaaattaat gctaaaagac tttgccacgc ccaagaagtt gtttgagata
    21841 atggattttg catgagtgtt gattgcatta taaatgcata tgctgcaaaa gacactggga
    21901 aaaaaacaat aagtttaccc ataaatgttc ttttatactt taaaagttct gattgtaaag
    21961 cattcatctg ttttgtcctc ctttaagaat aacatctgta aaaaattctt ctagattttc
    22021 attagggtca ggcattcctt gaaatagtag tcgtcctcca tttataattc ctatattatc
    22081 tacaacttga gcaacctctg atagaatatg gctagaaaga attacagtta tacctttttt
    22141 tggaaaagaa gcaatcaatt cacgcaattc ttgaatgcca aaggggtcaa gaccattggt
    22201 tggttcatct agtattaaca actctgggtc actcaaaagt gcaatagcta ttcctaacct
    22261 ttgtttcata cccatagaaa attgtgaagc tctcttttta cctgtatttt tcaaatttac
    22321 tatttccaac acttcataaa ttttatcttt aggtattccc aatatttttg tatgtactaa
    22381 caaattttcc tctgctgtaa ggtttccata caatgcaggg gattctatta aagaacctat
    22441 ttttgcaaga gattctcgtt tccaaggctt tctatcaaaa ataatacgac catctgttgg
    22501 gcgaagaaga ccaacaagca ttttaagtgt tgtggacttt cctgctccat ttggtcctaa
    22561 aagtccatat atactatttc gttcaatttg tagagaaaca ttgttaactg ccatttgttc
    22621 tccatatctt tttgataagt tttttgtttc aagaattaaa tctttcatat taatttctcc
    22681 cttcttgtaa taccttaaat ctattactaa gagaatacta acatgaaaaa ataacaattc
    22741 tataacacct actaatttta ataaaaatta aaataaaaaa tagagttacc aattttattt
    22801 tggcaactct atttaagttt atgttttaca gttatattag atttaagctt agtttcatta
    22861 tcacactaac ttcaaattta ctctataatc cttaaatcaa gcactaattt attaatcaaa
    22921 cactaatcta ttaatttata tttctttaga catctaatat agtttgctac taaataataa
    22981 ttacttatat catatttatc taatccttta aaagaagtta tttcatcatt aagctcatca
    23041 ctaccttcta caaaaacaca acctgtttca aattccatac ctacaataat cttacagcca
    23101 ctataagttt cctcttgagt atcgtacaat ttttttgcat ttccttcatt tggaattgta
    23161 aatacaatag gttttaattc tttatcactg gaaatctttt gtgaaaaagg cttgtttaac
    23221 ttaatattat tgataactac atgtttaaat tcctctgaag tttcttctac tattacatat
    23281 tttcgcttta aaaactctat tatttctaaa acagacttag aatttacttt taaaatactt
    23341 ttatattttt catataaaga tttccactgt tcaatttttt cctgtggtac ttcttggata
    23401 tgtgtactta ttttttcttg agatattttt ttcaattaaa ctctcctttc aatacttaaa
    23461 tatccttata aatctcacat gactaaagtt acaaggttcc tacttaatag aattttgcat
    23521 acttaaatat gtcttattaa ttctctacag gatatctccg tagtccctac gattcttaca
    23581 taagttacct attttaaatt gttattagtt agattataaa aattatttat tttatcacta
    23641 atataatact cttaaaaact ttacaaatca atttaaattt gctacctttt atttataaca
    23701 acttatagta catttctcct atgcttttca atatattact tttaaaagga ggttttcctt
    23761 atgattttaa atagaactga gcttttccga ggatattctt taaatagatt taacgagata
    23821 tgcaatatat tatcagtaaa taaaattaaa tataagtata aagtgaaaaa taatgcttac
    23881 tctaaaaaac ctttttctaa tgaaataaca cttggcaatt taggtcaaaa ggaagatttc
    23941 tcttatgagt acttaattta tgttcataaa gacgattatg aacaggcaga gtctctaata
    24001 aattctaagt tgcgatagat tatttataaa acatgacatt ctgttgtcat gttttatatg
    24061 ttattatact ttcaaatatg ctactatatt ttcaaaattg tgtgctttaa aactagcttt
    24121 ttatagtaat ttaaagctta aaactaagga gactcgttat atgaaaataa atataaaatc
    24181 aaagttaagt gaatttatta aacagaacaa tctttttgat gacaacagaa taatatccta
    24241 ccttcctaat ataacaatag aaacagacaa aataaaaact ataatgatta atgaggttgt
    24301 cccaactaac accaatgacg atttttatag tgtagataaa gatgctgatt atttaaaaac
    24361 tactattcct ttatttgaca gtgcaggaat agaagtatct aacataaatg atatcctaga
    24421 tatgggtatc tatataacta atgcagtaaa acttcctaaa tcagaatata caataactcg
    24481 tgatacaatt aaattacata tgcctatttt agaagaagaa attaaattat ttaaaaacct
    24541 agaggtagta atgttaatgg gagatgttgc aaaaaaatct tttaatatga ttactaaaaa
    24601 gcatataaaa aagaatgtca tcccttccat ttcaacatat aaacttcgta ataatgaact
    24661 ttattatgat aatttaagag tatttccatc atatattatg actggtggaa acatactgat
    24721 tgaaaaatca aaatttgaaa tggcatcaga agatataaaa aaaatgttcg agattataaa
    24781 cggttgatat tacaaaataa taaaaactaa tttagccaaa taataagtgc ctcaaaaact
    24841 tctatttatg aggcactttt attttatatt agtgtaacta tatactatta acataattta
    24901 ttatttatat tgttcttttt aatctctatt ccatttagtc taggtaacat tactctttac
    24961 aagattactt tatatttctt ttatatctct aacgttttta tttaataaaa caattattaa
    25021 tacaagtcaa atatatctat ttatctaaaa atatatcttt tacagtaata tctggatggt
    25081 gatacttctt cctattcgtt aaaaaagatt tttttacatt aatagcctct tttggacacc
    25141 agtgaaaaca agctaggcat ctttcacact cattacccca ctttggcttt ttatcaacta
    25201 tacttatatt ctctacagga caaacccttt tacatgtccc acatccatta catttatttt
    25261 ctgcaaaaaa tttagtagtt gcaatttgca tattcttacc tactaaacga agtacaacac
    25321 tatctatatg tgactttaaa ttgttttttc cttctatatt tccaatctcc aagttattga
    25381 tacattttgc aatctcagct accctattag tctgattttt caatctttct tcttcaacat
    25441 ctgaaggtgt tatcaaagca tttccaggca tattgattaa aaaaccagca gataattttt
    25501 tccccctttt tttaagtaac ttatctatag taaataaact atgtccagct accccattac
    25561 aagtggcaat ggcatatata tgagtattaa tattaaaatt taatttctct acaaaagact
    25621 ttattatatc aggaacatca gcaaaataaa caggaaaaac aattaccaat atatcttcat
    25681 ttatgtctat attattttct tttctatgta tagctaaagg tataacttct ttacttccat
    25741 ttaacgtttc ttttaaaatc tttgaaacta ctagcgaatt tcctgttcca gaaaaataat
    25801 aaatcttact attcattctt atccctcttt ctatatttct acatcatcaa tagttaaaaa
    25861 gtctcttaaa ataggattta tatttacttt ccaattctat ccaaaatatc agtaaacaaa
    25921 ggcaattctt catcagagat agatttaaat gtctctgttg catatatact tgcaatttca
    25981 tttaatggtt cttctaattc tctacctaaa tctgttagga atatttgaaa cttacgtcta
    26041 tctttaacat ctactttacg gacaattaat cccttatttt tcataacgtc taaaattctt
    26101 gttgtattag atttatcctt acatgatttt tcacataaat ctatctgaga aattccatct
    26161 tgctcccata gaaaccttaa taacgcataa tggtcagttg ttatatcata tccattttgt
    26221 ttaaacatct tttttaaatc atcttttact tttaacgaag tacttactaa cttagttgta
    26281 gcttcatata gtttctcaaa atctttcatt ttacctccat ttaaataatc ccctgctcct
    26341 cccatctatc aattattccc ttatattgct caatatcttt aaaagccatt ggctttaaaa
    26401 cagcatttat agcaataaaa ttatagattt gagaaagcac aggtggattt ttcttttcct
    26461 ctatgcaata aataaatttt ttagatacct tttgtatctt tgattctact ttttcagtta
    26521 taggattttg attaaatcca gtttttatag ataaactacc acaaacataa cctcccgaat
    26581 ctaagaccat ggattttata aaagaaattg cttttgaacc acgtgcattt tcatatgtag
    26641 taactgctat acatggctta cgatacaata atctttcaag catcatatgt gctctatctg
    26701 taaacacctt gaaaagtcca gttacactac ttccataagt tgggctacca aatataacac
    26761 catcactctt agtaattata tcatgaatat actctacttt atcattttga ttgatacact
    26821 tgcccatttt ataacaattt aaacaaccaa tacaatatga tggatttacc tcacttaaat
    26881 caaaataatt aatttttaca tctggtatta atctttctat atctttatac aagtaagtta
    26941 aaacttttga tgtagctcca ttttttctag ggcttccatt tataactgta attatcattt
    27001 ctatatctcc tttttagttg ttatatcaac aataagtata tcaactatat ttttagctgt
    27061 caatataaac catttattta aagctatact tacacagctt aaataaaagt tttatttaac
    27121 tacatgtgct tatttaatca actataaatg aattattttt aataattgac aaactaaatt
    27181 aatgataata tactttatgt attacaaatg taagtagaag gaggtatagt atgaaaaagt
    27241 taccacatat ttcagaagca gaatatcaag ttatgaaaat tatttggaaa tatgctccta
    27301 tcagcactac tgaagtaatt gaaaagttgg tagaaacaag tacatggagt cctaaaacaa
    27361 ttcaaacaat gttattgaga ttagttaaaa aaggagcttt aacatatgaa aaaaatagca
    27421 gagtattcgt ttatactcca cttgttaaag aagaagaata cgtagctaca gaaagtagtt
    27481 cttttttaaa tcgtttttat aatggtactc ttaattctat ggtactaaac tttttagaaa
    27541 atgataaact atctgaagat gatattgagg aactgagaga aatcttaaat aaaaggacga
    27601 ctaaggggga taaataaata tgtatgcccc attctttata cgatttttac tcagtacatt
    27661 aaccttatca atattaattg ttataatttt acttgccaaa aaagtattta aaaaacatat
    27721 ttctgcaaag taccaataca atattggatt tatattgctt ataatgttaa taattccatt
    27781 tgtccctctt aaatatatta atcttggaaa tgtatttaac tatttatata cttttaatca
    27841 acttggaagc agtactaata ggacttctat tataaaaaat agtccaaatt ctataattaa
    27901 taactcaaat gcattaaacg atttttcagt atccctaaac caagttaatt ttgatagttt
    27961 aaatatttta ttactaatat catggataat tggaatttta atcatgatag ctattactat
    28021 tcattgcaat attaaaataa aaaatatgaa aaaatcaata caaattttaa gagatgagga
    28081 gatagtattt atatttgaaa agtgtaaaaa agatattggt ataaataagg attttatact
    28141 atgcaaatca cctattataa atacacctat tacatttgga tactttaaac cacacattat
    28201 attaccagat aagtctatat ctaaattatc tttaaaagat ataaaatata tcttacttca
    28261 tgaattacaa cactttaaaa ataaagatat actgataaat tatataatgt gcttccttca
    28321 aatattatat tggtttaatc ctcttgtatg gtatgcattt aaagaaatgc gtatagaccg
    28381 tgaaattgca tgtgatattt cagttttaaa aaagcttgat aaagatagtc atatagaata
    28441 tggacaaact ctaataaact ttgtggataa tatttcaaga ccatcaaatc ttacacttac
    28501 atcagatatt ggtgggtcaa aaaaacaaat aaaaaagcga ctattgaaga taatggattt
    28561 tcataatgaa tcaaatacgt taaaattcaa aagcatttta atttttacat tgatagcttt
    28621 aattgtattt ggaaatattc ccaaactatc tattatggca gatatcaacg aaaaatatag
    28681 acctacaaat gaacaaactg tgtacgagga cttaagtcag tattttaaag gttttgatgg
    28741 aagttttgtt atgtatgatt taaaatccaa gcaatatcat atttacaata aagaaaaaag
    28801 taaaacaaga atttctccaa attctactta taagatttat agtgccttat tgggattgga
    28861 aaatgggata ataacaagaa ataattcaca tatcccttgg gatggaaagc atcattctaa
    28921 tagttcttgg aatgaagacc aagacttatt ttctgctatg gaaaactccg taaactggta
    28981 ctttcagact ctagacaaaa aaacagggct aaaaaacata caaacttatc ttaagcaaat
    29041 tggatatggc aattatgatg tttcaggtgg tatctcaaac ttttggctag aatcttcatt
    29101 aaaaatatca cctattgaac aggtagaatt acttgaaagt ttttatacaa ataagtttaa
    29161 atttgaagat aaaaatatag aaacagtaaa agattcattg ttaatatcaa aaaaggatgg
    29221 ggtatcactt tttggtaaaa caggcactgc taatataaat ggaaaagatg taaatggttg
    29281 gtttataggt tatgtggaaa aaaatgaaaa tacttatttc tttgctacaa atattcaaag
    29341 caaagattat tctaatggta gttcagcatc taagataaca ttatccatat taaatgacaa
    29401 aaaaatctat aatccttaat atatttactg tacattctaa aaaattcaca taattttcat
    29461 attaattatc gattaaattc atatacaagg cttattatat aaacatagaa gatagtaaaa
    29521 ctagcttaaa aacataatat aataccctat acaaatagtg gcaactctcc ctcacatcct
    29581 caattgttgc cactatttaa ttttttgtat gaagttaaat atattttcat catttcaaca
    29641 atttgggtgc agtacaatct ctattttgag acaacctctt taattgtttt agagtttatg
    29701 aattatttct catactttaa aaagattgaa ttactcttga taatcttctt ttgtagtcat
    29761 tacatatcac ctactactca acacatattc tttgacctat ttttacatcc ttgtttatat
    29821 ccaaaatatt taccttctta ccatctggaa acaataccat tgtcaaagta gactttccta
    29881 attcatgtat tctctttaaa tcaacattaa caagaacatc tccctgttta accatatctc
    29941 cttgtttaac agcaatatca aagccatctc catttaatgc aactgtatca attccaacat
    30001 gaattaatac ttctccatta gttcctttaa tcccaaatgc atgtccactt gaaaatactg
    30061 tttctaattt acctgaaata ggagaaacaa tttttccatc tataatatca atagcaaaac
    30121 catcacctaa cattttttta gaaaatgttt catctggtac attttctaat gcaacaattt
    30181 tccccttagc tggagacaca aagttttcat tattttcatt aaacactaat tcttcgtctt
    30241 catcttcatt tatagcttct ttaggcactc caaataaaca tgttacaata aagcagaatg
    30301 caaccacaaa tattgatact aataagtatg tgattaaatt atatccatca tagatataca
    30361 ttaaataaga aggtaaaact gctaatccat atgaattaga ttgaatatgt aaaattgata
    30421 atattgctgc tcctaaacct gaagatgcac acataataat caaaggcttt aaattatatc
    30481 gaagctgaat cccaaataaa acaggctcac ttataccaaa aagttgagat agcattgctc
    30541 caactgcagt ttgtttaact tgattatttt tagatttttt cataaatgct agacatgttc
    30601 caatattcgc aaatccatac attgcacaaa gagtaataag tgcattaaat cctgtatttg
    30661 ctaatagtga tgtttcaatc attacataag tatgatgtaa gccagtaata acagctaatg
    30721 gatatgtaaa tccaataata aatcctccaa ttcctaaagg taaaccaatc aataaactga
    30781 tgatatcaac catttttaat tctattgtat gcattatagg ccctacacct aacaaaataa
    30841 ctaacattgt tattagcata acaaagaatg gtgtgaaaat aaggtctaat acattaggca
    30901 tatgtttacg gaaccatttt tcaagattag ctccaataaa tgctgtaaca atagctgtta
    30961 aaacacttcc ttgacagcct acaataggaa taaatccaaa tgccataatt gcttcaactt
    31021 catttgatgg gtcagcaaca gaatatgcat taggaagtat tggagaaact aacataagtc
    31081 caataacaag tccaataaca ggtgttcctc caaatacctt aaatgctgac catacaataa
    31141 ttgctggtaa aaaagcaaat gctgtttctg taagaaccga aacaagtgtc tgaatataca
    31201 atggaatatt tgcagaagac attccaaata atccaagtac attatcatta aacaaacaac
    31261 cctttaatcc caagaataat cctgttgccg caataactgg aataatagga acaaatatat
    31321 ctgctagagt tctcataact ttcttaaatc cagtttcatt atttttaact aattcatctt
    31381 gttctttttt tgataaagtt ttcaatccca ttttttcaac ttctgcataa actttattga
    31441 ctattcccgt tcctagaata atttgatact gtccagaagt aaagaaaaca cctttaacct
    31501 cattaacctt ttccactttc ttatcattaa taatttctct atctttaacc atcaccctta
    31561 atcttgtggc acaatgtgta atagaaataa tattattttc accaataatt tcaataagct
    31621 catttgctat tttattatat ttattcattt ttctacctca ctttcaataa tactgcttga
    31681 aatggtttca aactcactgt tttatttagt agatttatat catctaaatt ttggaataca
    31741 atatcatatt tttcttctgt ttttatttct acaagtttat cagaaaaatt ataataacaa
    31801 tcaataacta ccaaatctaa ttgccttcta tacgcaataa cattgtcact ttctatatca
    31861 ataggttcta ttgaaccata aatcaaacaa tcagaatact tactatcttg tctcaacttt
    31921 atcatctttt tataaaattc taaaatactt tctgaattgt taatctgact ctgtgcatta
    31981 atatctttat aattttcaat aacctttaac catggtgttg catctgaaaa acctgcattt
    32041 tctttatctg cccatggaaa tggcgttctt gcattatctc ggcttcttaa attcacaaat
    32101 tctaacgctt cttcttctga gtaaccttca tctattgaac gatagtattg gtcaatgcta
    32161 gataaatcat taaaatcatt tatggtatct cttttaaaat ttgtcattcc taattcctgt
    32221 ccctgataaa taaatggtgt tcctcttaaa aagaaataca ttgctcccaa catttttact
    32281 gcatcatcat tcctttcgta ttgcaaaaga tactttgttg tagctcttgg ttggtcatga
    32341 ttttcaataa aattagctgc ccatccatgt tcctgaacat acatttggct atctaaaatg
    32401 cattttctta aatctggaat tgtccatgaa attcttttaa accactcact accagaagca
    32461 acatctaagt cagcatgttt aaagtcaaag accattgaaa agaaaccatc ttctccaata
    32521 aaatcaccta gttggtcata gctaatacct gctgcttcag caacagtcat acaatcatat
    32581 tttttaaacg tattttcttt taattcataa agcatttttt ctattccagg ctgatttcta
    32641 actgtttttg tacatttaac aagaccatca acaccatcac tttctaaact ttgaaaactt
    32701 aaattctttt tgataaatgt aatagcatca actctaaatc ctgccactcc catttgagac
    32761 caggtattaa tcatttggta aagttcactt cttaatattg gattttccca attaaggtca
    32821 ggttgttttt taccaaaaga atgaaaataa tattcgtctc tattctctac cttttcccaa
    32881 acacttccac caaaaacaga cctccagtta tttggtaaat cgtttccttt tttaaaaata
    32941 taataatcat gataaggact ttctggattt tttaatgctt cttgaaacca aggatgttca
    33001 tcacttgtat gattaagaac taaatctaat ataattttga ttcctctatc tttactttct
    33061 ttaattaact cttttaaatc ttccatactt ccaaattcac ttgcaatatc taaataatca
    33121 ctaatatcat acccattatc gtccataggt gatttaaaaa ttggacataa ccacaatgat
    33181 gtaataccta aatcttttaa ataatctaaa cgagaaataa ttccctgtaa atctccaatt
    33241 ccatcattat tactatcttg aaagcttctt ggataaattt gataaacgat ttctttttgc
    33301 caccatttct tttccataaa ttactccttt ttatatgata tttcttcttt ttaattcttt
    33361 ataaattcca ttatcgaata tgtcctcaca tatagatgtc gctatatctt taagttgttg
    33421 atgactattt ttcattgcaa ttgtaacgtc tgatgcttga aacatgacaa tatcattttg
    33481 accatcacca aaacatatgg tttctttttg agttacccct aatctttctt gtaatctctt
    33541 aattgctttg cccttatgaa aatctttttg aataatttca taatactgac tagaaatatc
    33601 tctctgtgct aattccattt tatcttgtag tatatctttc acttcgtcaa ataccttttc
    33661 atttgaccat aaacaaattt tatgtacatc ttgtgactta tactcttcaa tattattttc
    33721 atatgttatt ttttcttgga tatgttgttt atttatacaa gaattagttc ctttcaactg
    33781 attcattgtt tcaaatattt ctttggcttt ttgattcatg aaaacttttt cctgactctc
    33841 aatcgaaaaa gcaacttctc tcttttttaa caaacaaaca acttccttta tcaatctttg
    33901 attaaaagat tgattataaa gtaattcacc atgatattga atgtaattac ctcctcctgc
    33961 aatatatcca tcaaccccta atgataaaac atcatcttgt attgtaccta tacttcttcc
    34021 agtacaaata acaacactgc aatgattctt ttgacataaa cgtatagcgt gctttgcaga
    34081 ttctgggatt ccatatacct catccctaag cgtaccatct atatcaagta ttaataattt
    34141 gtacaatttc atcttccttt cttactatca aaatcataat agcattcaaa aaaaaagata
    34201 tcaatatttt gatatctttt aaaaaatatg ttcattttta gcacaaattt tcactttcgg
    34261 ggaatatgtt cactttctaa atacatcttg tatttaatat aaagcagttc aattaaaata
    34321 aaataaggtg ttgttacatc gtagtccagt tgtttatcta cagaaataga tatagattga
    34381 atatacaggt tttcatcaca taatcttgct aaaggattac ttatcatttt tgtaatagaa
    34441 accatataag ttcctttcat tctcatttct ttagcaaaat caataattgt agatgtatct
    34501 ccattcaatg agataaagaa aatcatatca tctgttttta taaaatgatt aagcgcctga
    34561 atcatatcat aaccataaac atcatatata attttccctg ttggtaagaa aatccttttc
    34621 atctctttaa caactctttc ctgagaataa ccttctccaa agacgattat acgatttgcc
    34681 tttttcattc tttcaaacat aatcgaacaa tccttcttct ctatatcatc tatcacctta
    34741 ttataacaat ccattaattg gtgtttactt tgatttttat attctacttc tgtttcattt
    34801 aagcgtataa taactcttaa ttcactatat ccaggtaatt gtagtttttg agcaaaacga
    34861 gaaagtgcac ttgtagatat atggtatttg tctgcaaatt catctataga aagtttaata
    34921 caatcttctt tatgattaag aatacactca cagatatact tatcatttgc tgtaaatgaa
    34981 ttataatatt tattgaaaag tccttcaatt ttcattcttt tctccttcta tactctatgt
    35041 aattcatatg aagcaaatct aatagagcat aaaatgctcc tacgacttca taagatatag
    35101 cttgtaatgt atcaagtttt tgagtttcaa catacagatt atactcacaa agtgttgcaa
    35161 ttgtattatt atcaagccta gttaaagaaa tcgtatgtat atgattgttg ataaattttg
    35221 caatttcaat tcctgatttt gtttctccag acaaagaaat gataataaat aaatcacttt
    35281 tttgaaatga ttctctcata aattcaattt cacctatatc aaataagtca ataacacatt
    35341 tacctactga aagaaatatt ctctttattt cttgagctaa acttttctgt tcattacctg
    35401 tcccataaat ataaattgtt tctgcatcat atattatttt acaaatatct tgaaatgata
    35461 ttttttgtaa ttcattcatt aatagtcgat aattctcgca aacatcatga aaattattat
    35521 cattattaac aaattctagt tgattatttt taagtaaata ctttaaatca gagaatgaat
    35581 ctaatccaat ttttctacaa agccttaata aagtagctct agaaacatta cattcatttg
    35641 caattttttc acacgaaaaa ttacggtatt ctctttgaca aatcaatatt tgtttaataa
    35701 taattttatc attttcattt aaactattat aactttggtt aactaacgat tctaatctca
    35761 ttttttccac tccctaaata ttattttaat atacattagt tgctttttct agtgaagagt
    35821 cttaaataat aaggataaaa taatcatttg attttatttt tattaaaata aaaataacct
    35881 gctaaaagca ggcaccaaaa agtacttatc ctttcgaaca tgtactttag atattgcttt
    35941 cttcggaagc ttcatctctt catactctaa aatagagttt tttctaactc aaaagtattt
    36001 tccatggtag aaattacttt aattcatctg ccatttattt tttatcttat ttaataatta
    36061 ctattacttg aatatttact tctttaagta aatttcatag ttaacaaagc taaaactatt
    36121 attatagatg ttaaaataca aaattataag tattgttata aatatgctta cagctacaaa
    36181 tatacatgat atattaaaaa gaagctgtaa attattatca tacatacaag caactatgcc
    36241 tctattaatc catgttaatt tttattattt aatacaagga gttccatgag acatacatat
    36301 ccattcatat tttaaattat ccaattctct tatagatttc atcatctttt tataatccca
    36361 attccatgga ttaggataag gaactatatt tccattctta tttttgacta aatcacctgc
    36421 aaataataca tcttcaaaaa tcatgcagac atgccctgga gtatgaccag gagtatggat
    36481 aatttttata ttcccaatct tcatattctc tccataaggt tcaacatcct taatgagcct
    36541 tctggaaatt gcctttccaa taaacttctt aaacccaggt ctatccttct ctcctataat
    36601 aaaaggtata tcctctacat gagcccatac ctttgctcct gttttctctt tcaataattt
    36661 aatattagat atatgatcaa catcatgatg agttaataaa atatgcttaa tatctgtaag
    36721 tttaatgcca agtgttttta attctttaat tatatttttc cccataaaag gaagacctgt
    36781 gtctataaga ataatttctt tatcgaacac aataaaacaa tttgaaccac gagtactatc
    36841 taacattaat acattttctt ttatcttcat aaataaattc cccttatttg gtattttacc
    36901 tatataatta attaataaag ttataaatag ttataatact tgatattaat tttatttttt
    36961 attaaagtat actataggta tacaaatatt atatttacat aagtatacca tcagtatact
    37021 tttttatcaa tagaaaggaa taatttatat gtcagaatta tcaaaaagag ataaagaaaa
    37081 aatacaaaga gaaaatgaga ttattgataa ggcagaaaaa ttattttgtc ttaatggatt
    37141 tgattaaaaa atagctacgc acact
//
LOCUS       DAEQJM010000034        36754 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.034, whole genome shotgun sequence.
ACCESSION   DAEQJM010000034 DAEQJM010000000
VERSION     DAEQJM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36754
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.034"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..146)
                     /locus_tag="KRQ43_002104"
     CDS             complement(<1..146)
                     /locus_tag="KRQ43_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBH2742460.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGI"
     gene            complement(629..1546)
                     /locus_tag="KRQ43_002105"
     CDS             complement(629..1546)
                     /locus_tag="KRQ43_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBH2742461.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIETVKEFWE"
     gene            1808..2185
                     /locus_tag="KRQ43_002106"
     CDS             1808..2185
                     /locus_tag="KRQ43_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH2742462.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            complement(2341..2790)
                     /locus_tag="KRQ43_002107"
     CDS             complement(2341..2790)
                     /locus_tag="KRQ43_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2742463.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(2968..3372)
                     /locus_tag="KRQ43_002108"
     CDS             complement(2968..3372)
                     /locus_tag="KRQ43_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBH2742464.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            complement(3485..4351)
                     /locus_tag="KRQ43_002109"
     CDS             complement(3485..4351)
                     /locus_tag="KRQ43_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH2742465.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMSPEQIINLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRSTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            complement(4921..5265)
                     /locus_tag="KRQ43_002110"
     CDS             complement(4921..5265)
                     /locus_tag="KRQ43_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBH2742466.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            complement(5454..6071)
                     /locus_tag="KRQ43_002111"
     CDS             complement(5454..6071)
                     /locus_tag="KRQ43_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742467.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKNLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            complement(6076..8247)
                     /locus_tag="KRQ43_002112"
     CDS             complement(6076..8247)
                     /locus_tag="KRQ43_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBH2742468.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNED
                     TINKILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVS
                     REASILRLNGYSKLDIIARVIKNIFRIMILSSVTALLIYIIYILKLNIGVRACLYFAM
                     FSIICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSI
                     NNCILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLV
                     EEKDAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGK
                     EIFNLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKT
                     KKSDLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIIDIDNIDDSFYLSYISRCV
                     YFNSKKLDALADISNIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIA
                     ISNLMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRV
                     DLSNNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            complement(8662..9294)
                     /locus_tag="KRQ43_002113"
     CDS             complement(8662..9294)
                     /locus_tag="KRQ43_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBH2742469.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGEILCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINLENLHIWLENGVDVCGFGGLLTKGTIEDITENAKKIREIIKNIREI"
     gene            complement(9400..10305)
                     /gene="dapA"
                     /locus_tag="KRQ43_002114"
     CDS             complement(9400..10305)
                     /gene="dapA"
                     /locus_tag="KRQ43_002114"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH2742470.1"
                     /translation="MKYKGIICAMITPFDEKQNINSQATCKLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVIDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEVTQNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            complement(10310..10909)
                     /locus_tag="KRQ43_002115"
     CDS             complement(10310..10909)
                     /locus_tag="KRQ43_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH2742471.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIVLQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            complement(10967..12238)
                     /locus_tag="KRQ43_002116"
     CDS             complement(10967..12238)
                     /locus_tag="KRQ43_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBH2742472.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            complement(12265..12552)
                     /locus_tag="KRQ43_002117"
     CDS             complement(12265..12552)
                     /locus_tag="KRQ43_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742473.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            complement(12567..14654)
                     /locus_tag="KRQ43_002118"
     CDS             complement(12567..14654)
                     /locus_tag="KRQ43_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH2742474.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPYNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIYLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            complement(15221..16075)
                     /locus_tag="KRQ43_002119"
     CDS             complement(15221..16075)
                     /locus_tag="KRQ43_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBH2742475.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            complement(16107..16619)
                     /locus_tag="KRQ43_002120"
     CDS             complement(16107..16619)
                     /locus_tag="KRQ43_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBH2742476.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDKKKGN"
     gene            complement(16612..16836)
                     /locus_tag="KRQ43_002121"
     CDS             complement(16612..16836)
                     /locus_tag="KRQ43_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742477.1"
                     /translation="MNEKPSFKQIEIILAVIFLVLTYYKIGLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            complement(16896..17849)
                     /locus_tag="KRQ43_002122"
     CDS             complement(16896..17849)
                     /locus_tag="KRQ43_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH2742478.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLESGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            complement(17877..19265)
                     /locus_tag="KRQ43_002123"
     CDS             complement(17877..19265)
                     /locus_tag="KRQ43_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742479.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPNNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKAGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            19538..20419
                     /locus_tag="KRQ43_002124"
     CDS             19538..20419
                     /locus_tag="KRQ43_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH2742480.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            complement(20606..21598)
                     /locus_tag="KRQ43_002125"
     CDS             complement(20606..21598)
                     /locus_tag="KRQ43_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBH2742481.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKKIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(21603..22343)
                     /locus_tag="KRQ43_002126"
     CDS             complement(21603..22343)
                     /locus_tag="KRQ43_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBH2742482.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLVGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGDTKVEDIGVLYKIMKELLG"
     gene            complement(22408..23517)
                     /locus_tag="KRQ43_002127"
     CDS             complement(22408..23517)
                     /locus_tag="KRQ43_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBH2742483.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFL
                     IIEELVNKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEINFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDNIYNRIKNIVES"
     gene            complement(23535..24668)
                     /locus_tag="KRQ43_002128"
     CDS             complement(23535..24668)
                     /locus_tag="KRQ43_002128"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBH2742484.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNHIDDSKYQAKQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGEFY
                     EDTKKYKTNVYALINIAKQGITSQDELSNMMNIDEYELKNAVRKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEAKERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGNSIEENE"
     gene            complement(24670..25764)
                     /locus_tag="KRQ43_002129"
     CDS             complement(24670..25764)
                     /locus_tag="KRQ43_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH2742485.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMVSKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNEYQVVFNVVAKEKTSEVEKIIMVNEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNKNIFKRGDVVIGNDDFGKYKGELQLILQDCTDERK
                     NKVGRIKEDEIILLDFIEPWSKFKIILEGE"
     gene            complement(25901..27202)
                     /locus_tag="KRQ43_002130"
     CDS             complement(25901..27202)
                     /locus_tag="KRQ43_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2742486.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKATLDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            complement(27426..28127)
                     /locus_tag="KRQ43_002131"
     CDS             complement(27426..28127)
                     /locus_tag="KRQ43_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2742487.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            complement(28340..28657)
                     /locus_tag="KRQ43_002132"
     CDS             complement(28340..28657)
                     /locus_tag="KRQ43_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH2742488.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SKEVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            complement(28705..29016)
                     /locus_tag="KRQ43_002133"
     CDS             complement(28705..29016)
                     /locus_tag="KRQ43_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742489.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            complement(29165..29644)
                     /gene="rlmH"
                     /locus_tag="KRQ43_002134"
     CDS             complement(29165..29644)
                     /gene="rlmH"
                     /locus_tag="KRQ43_002134"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBH2742490.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIVLAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            complement(29712..31814)
                     /locus_tag="KRQ43_002135"
     CDS             complement(29712..31814)
                     /locus_tag="KRQ43_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBH2742491.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEKEI"
     gene            complement(31827..32624)
                     /locus_tag="KRQ43_002136"
     CDS             complement(31827..32624)
                     /locus_tag="KRQ43_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2742492.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            complement(32726..34189)
                     /locus_tag="KRQ43_002137"
     CDS             complement(32726..34189)
                     /locus_tag="KRQ43_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBH2742493.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            34314..35372
                     /locus_tag="KRQ43_002138"
     CDS             34314..35372
                     /locus_tag="KRQ43_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH2742494.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            35381..36373
                     /locus_tag="KRQ43_002139"
     CDS             35381..36373
                     /locus_tag="KRQ43_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2742495.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKEKLLSESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
BASE COUNT        12218 a         6356 c         4043 g        14137 t
ORIGIN      
        1 tagattccta ccattccatc agacccaaat aacatcccta gtaagataaa aatcaataat
       61 attggtactc caaatttata caataccttg ctagaagtta tacaaatcaa tagtactaac
      121 ccacttataa tcattaattc tgtcatagca tcaactccat ttcatataaa ttttgtagat
      181 taatttgcat ctacaatttt attacttatt caaatataac atgacataaa ttttataagt
      241 tatggtacat aaagttcaac aaaaatttca caatacatta aaatgtgagt gttatactta
      301 aatttatata tttgttttaa ttatattcat ttaatattta taatttgaat tttttttatt
      361 aatatttcat tttttagttg attgtttaat atatttcatt ttttatagta attttatata
      421 taactacgaa atataaagta attagataag taacaagaaa ctaacatgta atgttaggta
      481 ctctagatat gaaatcttaa aacttttaaa tattgaaata tttctttata tatattattg
      541 tatatttctt ataaattatt gtcaatttat tttttcttaa aaataaaata attgcataat
      601 ttatttcaaa ttatgcaatt tataaaattt attcccaaaa ctcttttact gtttcgatta
      661 tctcactata aggcaataaa gtcgcttcga ttattgattt atttgtcttt tctaaataat
      721 acttaatcat ataatatcca caagcatatc ctgcacaata aggcaaccct actggaaaat
      781 atccttgcat tttagctata tcatcaccat aaagataaga tgttatattt tgaaatccag
      841 tttcttttaa agcacttttt attattggct ttatataagt atttaatgtt tcgatatctg
      901 ttctactgac ccaaggtcct aacatttcct ctccaaacat ccatgttgca aaattttctg
      961 caagaccttc atttatcatc atttcttcta atgttatatt attattccac tctataaact
     1021 gaaatctaat attgtgatta cattcatgtg ctattaatac tggtaatcta ttgatagtat
     1081 attcattagg aaccaatgat agaaatatat atccaggaat cccaccatca ccccagtatc
     1141 catcacttaa tattgtataa ggactatttg gattcgccaa taatattgaa tatttatagt
     1201 ccttaatgtt taaatcatac ccttctttta taaaagcatt tatagagttt tctatggttt
     1261 ctttgcaagt gccccaaatt ttatcagcag ataacacatt tatattcttt ttttgctttt
     1321 catcaatatc cttaggcgat aaaaccccta acatttcact tgctataatt acatcatatc
     1381 cacctttctg tctagcaact attggaacat tcatacactt ccacttaaat tcaaaaggct
     1441 tcatcaattc atatctgtat atatcttctt ttttgtttat tggtgcatcc attatcttct
     1501 tgtatatttt atctgagcga atttctataa tattcatatt taccatctcc tttaagacaa
     1561 agtatataca attacgtagc gtcaatgtca atatacattt tttataatgt caccttaatc
     1621 tttttattat attttatcct gtaaaccttc cgtacatata acattttttt aaattaataa
     1681 atttgtataa tataataata aaaaattata tacttcaagg tttccctatg atacaattta
     1741 ctaaatcata atttagatta tcaggtgcaa ctataaatta ttctatatca aggaggatat
     1801 attggtcatg ctaactccat atttaatatt taatggtact tgtgaaaaag catttaattt
     1861 ttatgctgag gctttcggag gaggaaaaac tatatttgcg cgattagaca gcaatccaaa
     1921 caatcctatt atgcacgcaa gtgttacttt cacaaaatac gaaggttgta taatgggtgc
     1981 ggatacagac aagcctgttg taatttctgg catggcgatt tgtgttgttc taccatctcg
     2041 agaagcgata gaagaaatat ctgtaaaact tgccgagggt ggtacacttg tacaagaatt
     2101 tttaccacac ccaccaccac atcaaaatga tggcgctgct gaagtacttg ataggtatgg
     2161 gtatacttgg tatttaagta catagtaaaa ataaaaaaac tacatctaat aatcataata
     2221 tagaacagat aaatttcaat ttaatagtgt agtaaaaaag tcgtgtccta agactgtcac
     2281 gacttttatt tgtataaaaa tttaagtaaa tatttttgcg aataagtgag aagtataact
     2341 ttaaattaat ttcatatgta gtattggaaa tgggttacct tgtccatcta tttcagacct
     2401 atcaaacact ttaaatccta agtgaatata aaatcctaca gcttttttat tctgctcatt
     2461 tacatcaaca tattttacat tgtatttatc tatagcatat tttattaatt ttttaccaat
     2521 accatttcct ctatatttat cttctataaa gagcatctca attttatctt tatctattcc
     2581 tataaagccc tttattatat cattatcttt tatacaaact atattttcta cttctttaag
     2641 tccaatttca actaatggta tcaaagattc aatatctttt tctgttaaaa aatcatgcgt
     2701 tgctcttact gatgattccc agacttgcaa catttcgtca tattctgttg aatttatttg
     2761 tttcatttca agaattattc cagatttcat aaaatttcct ccctatatca cttttaattg
     2821 tataacactt ttttatacaa aacttagaaa ggactacgaa ggttaagtat catagtccta
     2881 attaagttta aatattatct attatatatt tttaacattt attatatact ataatctagc
     2941 aaatttacta caataatcca tatcagttta tactaaaggt gcttctattt gagtagtaaa
     3001 aaggaattta tgacaatgac catcattaac agtagtttct ccacatatta agtgaatgtg
     3061 tttatcagtt ccaggtattc taattgctgg ccctgttgta acacatatct tatggaaatg
     3121 gtcaaggaaa tctacattat catttatttt atgaacatga tttgtacctc catttattgg
     3181 tatagcttca ccagtaaccc ctgctgcacg gtggttatgt ctatcctcac attcttctgc
     3241 taacttaaca ctttctgaat attcatgaac atgtgtcatt tcctcataat cattatagca
     3301 cttgttgcac ttattgtatt tataatcatc atacacataa tctctttcac atttataatt
     3361 ttgataactc atttttatat ctctccctat attatattaa gaaattcttg taaagaatct
     3421 ctaatgtata atatgaatta aagtcaaaaa agttcatatt ttgtaaaatt atgtattaat
     3481 ttaattattt ctcccagtat ttagggcgta ttagtgaagc tggtaacttc gtactagaat
     3541 ctccttttgc agtatttact tgcaattgtg ttaaaaatat actattttca agattagcac
     3601 ctctaatatc acaatctctt aagtctgctc ctattaaatt tgccccactc aaatctgtac
     3661 ttcttaaatt tgctgctatt agaaatctac ctcttaaatc tgctcctatt agatttattt
     3721 ttctaaggtc tgctcctatt aaatctatat ttttacttaa ttttttcata tttttaagag
     3781 tagaagtctt gataaatgat ttaacctttc ccatcacaga ctcactcgct tgtgataata
     3841 ataaattaac ctttgttcta tgtgatatga tatccaaatt aattatctgt tctgggctca
     3901 tattagttat cttttcagtt tcttcaatta tcaaatcaat ttttgatttg attgtatctg
     3961 atatatttaa tacagatgct tctttaagat accataacat ttcatgtaat tgtctcataa
     4021 ttaaaaacac ttcagacatt tgatttgtta attctggtga ttgcatccag tctatcccct
     4081 tatatgttac ttgtgctact ttttgacctg aaccaaaaca atcatatgca gtacaccctt
     4141 taaaacctcg cttcataaga ctattatgta cagaacattt aaaatctggt tgtaaattaa
     4201 tacagggttt tcctgattcc ttatcgatag gaaatccatc tgaagcagaa aaataaagag
     4261 ctacacaaca aagtccaaaa cacttcttac aatcaatctt tagctcctca aataacttat
     4321 tatcatatat atttttatgt atatctatca tattttttct cctcttaagc tttattttta
     4381 atattatatt atctataact aaatgataat caagtccctt atttaacagt tcttattctt
     4441 aattataatt taaggtatta tttattccaa tagcatacat aagtttcttt atacttgtaa
     4501 caataccttt atactaagac ttattttaaa tgtagcactg taataataaa ttgtttatat
     4561 actcataatg tatttgataa attgtaaatc tttatagaag ttgaaatttt taatgatttt
     4621 agaatcaaga tataataata aatacaattt ataaaatcag aaatatataa attaactata
     4681 caaacctaaa taacatagca tttaaattca caatttcagt ataaatagta caaagtatat
     4741 taatttaaat aagattggct tatttgtaga ggagagaata ttttggtgtt caataaaatt
     4801 tatatttaat aaaaccataa gaaaatataa agataaataa acaaactttt attacttaat
     4861 agattcttat ggttttatac tgtactgaaa aacaataaac actacagctt atttataata
     4921 ttacgctttt ttaacaacag aagactttag cttcatagct ccaaaaccat ctatcttaca
     4981 ttctatatca tgtccatctg atgagtcatg gattaaacgg atatttttca cttttgttcc
     5041 aatctttata gatgatgaac ttccttttac tttaaggtct ctaattactg taacagaatc
     5101 tccatcattt aatacatttc catttacatc tttgataata tttgaatctt cttcagctcc
     5161 caatcctaat gcccactcat gagagcattc tggacaaact aaaagagttc catcttcata
     5221 agtatattct gaattacatt tcgggcaatt tggtaaattt tccatcttta tatgtcctcc
     5281 atttgttatt tttaaatttc ttattatata aaatttcttt tgagccttta tgatatcata
     5341 ttatacttat atttacaaac tactaattta cttaatgttt aaattctatt cgtattatta
     5401 ttaaacttga tttagctgta atctctttct tatatttatt atagttgata ttattacaat
     5461 tttataactc tatctgcctg ctccgataac tctaaatcat gagttacaaa tacgatagtt
     5521 ttaccattct tatttagatt tttaagtata tcaaatacta tgtctctatt ttttttatct
     5581 aaattacctg taggttcatc tgcaaatatt acttcacatt cttttaatat tactcttgct
     5641 aatgctaccc tttgttgttc tcctccactc aattcgtata tctttttttt attgtatttt
     5701 ctaagaccta cagactcaag tgcgtaattt attttttcat tatggttgat atttttttga
     5761 tactttaaag caattttcaa gttattttca acattttcat tctcaattaa agcataattt
     5821 tgaaatagat agccataaaa atccctttgt aaaattctta tctgtttact atttggattt
     5881 tttatattat ttattataat atcaccagaa ttaggttttt ctaataatcc cattatatta
     5941 agtaaagttg tcttacctga accactattt cctgttatcg ctacaaactc gcccttagaa
     6001 atttctaggt taaatttgtc tattatagat ttatctttaa attttttaga tatatttatt
     6061 aatgaaatca tctttttaat gttctccttt tataatttta ttaaatgaac tatttgagat
     6121 aatcttgtct aatacaatag atacaattac ttctataact aatatcagaa gtccaaataa
     6181 gataatatta ttacttaaat ctactcttgt tgatataatg cctattggaa taatgtttgt
     6241 taatattaat gagactatta acaacatact tctagctgta gttgaataac caaatatttt
     6301 tttaatatat aacttatatt tatttctttc atagtagcta gctactatat tgtaggtaat
     6361 cattaagttt gatattgcta ttattattat agtaaaaatt tcactattca aatatttttc
     6421 tagtttattt atttctaaac catactcatt ataaacagca tgtaaacttt ggatatgcgc
     6481 ttctacacct tgagcttcaa taatgttact tatatctgca agggcatcta atttcttaga
     6541 attaaaatat acacatctag atatataaga aagataaaaa gaatcatcaa tattatctat
     6601 gtcaattatt gctattgggt catcaatgag attcctattg tcatccataa caagggagtt
     6661 ataagtaaaa tagctttgat tattatctac atatattata ttaacattta aatctgactt
     6721 ctttgtttta tttaactctc tatttaactc tttattgtac atattttcta cttctatttt
     6781 ttcaaaataa aataattctc taaactcttt tttaatctca ttttcatgta cttgtaactt
     6841 tttaggaact aataaattta tagtcttatc gtcataatcg attagattaa atatttcttt
     6901 gccatttgag taaatagggt taactttaag atagttttta tttattttta tatttttacc
     6961 atattgactt acttctgggt ttttaccctt tgaatttatt tcatacatgt aacttccatc
     7021 ttcaagtttt tcaaaattag ttgaatctat taagaaagca tctttttctt ctaccaaatt
     7081 tttatagaaa cctttaatct tggcattttt aattacttct tcctttccta aagattgttc
     7141 gcctgtatct ttaagagtaa gattataaac attttttgct ttatcccact cagatagatt
     7201 tcctaactga gtttgtagca tattataatt taaaatacag ttatttatgg ataatataag
     7261 aaatgataca aatacaattt tcaatgtgaa atgcattata tttacaaaac cataagattt
     7321 ttttccattt agagatagca catatttaga acttctacta ttaaaaccaa ctattaatat
     7381 agatatcaaa atatttatca aaatacatat aatcgaaaac atagcaaagt ataagcatgc
     7441 tctaacacct atatttaatt ttaaaatata gattatatat attaataatg ctgtgacaga
     7501 tgataaaatc ataattctaa atatattttt tataacccta gcaattatat ctagcttaga
     7561 gtatccattt aatcttaaaa tagaagcctc tctactcaca ctaattgaat aatgtattat
     7621 tgtagccaag aaacaaagga taattagtat taaatctcta attattgaag gatttaagta
     7681 taaatttgag ttaacatatc tatcatgtaa tcttgctaca aaaatacttc tgtctacatt
     7741 tagttctctt aatattttat ttattgtatc ttcattttga gttgaaatat ataagattcc
     7801 tgattctcca acttcactta ttttaccaaa atccctaatt aaaattgata tgtctttact
     7861 catagttgag aatttaccta cttgattact attattacta ttattagtgt ttatattact
     7921 aataaattca tttgaattag tattaggaaa ttttcctgat tttaacttta tattgttatt
     7981 caaacttgta tcagtcgtat atatagataa tttttcatta ttattaaaaa catactttga
     8041 tatagccaca ttattttcat ctgcaatatc tttaatccac ttactataat ttttatttaa
     8101 ctttttataa tctttaaaca ttacagatat acttgttgta tcgttatata aaatattatt
     8161 aatttcatta tctttaacta tatttagacc taataaagat actattaata gttcaattgt
     8221 aaataataca tatattatct ttttcaatta tagctccctc ctaattgttt ttattctaaa
     8281 agcaaaatat attttacttt agttaaagta taatgctttg taccttttct aaacaactac
     8341 tatattgtca cattctaaat ggcaagtgtc tatttcgtca caaagataaa aataacctta
     8401 aaacagttaa ttttttataa tcaactgttt taaggttatt ttttattttt agcaaacaat
     8461 attttaatag tggtacaaaa ttagtataat tcattaatat agattctagt atttttagca
     8521 atcaactaaa ataatatctt atttaaaaca aaatttaatt taagttcaat ataaacttta
     8581 cctcaactag aaaatatttc ttctaactta ggaattaatg tgtggatatc tcgtcaatag
     8641 aaaactaatt catcctccat gttaaatttc tcttatattt ttaatgattt cacgaatctt
     8701 tttggcattt tcagtaatat cctcaatagt tcctttagtt aataaaccac caaatccaca
     8761 tacatcaact ccattttcta accatatatg taggttttca agattaattc ctccacttgc
     8821 taaaactggc atatcaggta ttggtgtctt aaataccttt actagtttag gtccatagaa
     8881 atctgatatt gggaaagctt ttataaaagt cgctcctaaa cttagtgcat ctactgcctc
     8941 agtcaatgat gtacatcctg gagcataagg aatctgatat ctattgcaaa tcttcgctac
     9001 accttcattg taatttggtg caataataaa ttgagctcca tgtaatatag catgacgagc
     9061 tgtttcacta tccaaaactg ttcctgctcc cacacaaagt atttcaccat actttttatt
     9121 aagcccttga attatttctc cagcattatt tagggtataa ctcatttcta taactgttat
     9181 accacctttt atacatcctt cagcaatttc acatgcacgg ttaagatttt cttctcttac
     9241 aattgcaaga gccccacatt ctgacattct tttggttata ttcatctttt tcatattatc
     9301 acctctatac tcatcaaacc actttactta ttcattaatt ttagtcatgt tttataatat
     9361 atatattaat tatataccag tgtaatttcc ctatttatat tatctattct cactactttt
     9421 attaagtatt gtcctataat tttcaactac tcgtttaatt tcttcaagta cttccccagt
     9481 tggttcagtt acaggaagtc gtgcagttcc aacattaatt ccattcaaga caatagtttt
     9541 cttcataaca gatggaattg ttccaagttt tagtatacgt cgaagttctt ctatactact
     9601 ttgagctttt tgagcttctt ccaaatcccc tttcataaag ttttcataga tagaaatacc
     9661 aatctctgtg aggaagtttg ttgttgctgc aacagctcct tgactaccag cttttagact
     9721 atccagaata agtgaatctg agcctgaaaa cacactaaaa ttctcattct gcgttacttc
     9781 aatataagct ttcatgttgt caagtttacc actactatcc ttaattccaa caatattctt
     9841 tatctttgat aattcacgta ctgactctgg ttcaatatta attccagtct tacctggcat
     9901 attatacatt ataataggta aattaactga attagcaata gttttgtaat gtaagattaa
     9961 ttcctgttgt gttggtgtaa caaagtatgg tgtaataata gataatgcac ttgctccaat
    10021 cgcttccatt ctcttggata aatctataac ttcacgagtt gaattaccac ctgttccaac
    10081 aaaaacaggt acacgattat ttgtatgatt aataacaatc tttgcaaatt caactttttc
    10141 atcatctgtt aacacatgac attcaccatt agtacccaaa ataaataatc cataaatccc
    10201 cttttcaatc aaataatcaa ttaatttaca tgttgcttgt gaattaatat tttgcttttc
    10261 atcaaatggt gttatcattg cacatataat ccctttatat ttcataaaat tatattccct
    10321 ctctaataga ctttccaaga cttcctgctg gatgccattt caaatactgc tgtgtattaa
    10381 gacctttagc atattgtaat acaacactta atgattgtaa tactattgtt tcagctaaaa
    10441 ttgaagcacg aggagcttta ttaagacaat ctccttcctg tttaacgcct gcgaacagga
    10501 atatatcaga aatatttttt aaaaatgaac tctcattacc acttacacca attatttttg
    10561 ctccatttac ttttagagtc ttaagagttg cttttaactc ttgagtttca ccactatttg
    10621 atattgcaat aacaacatct ccttcaacta cttgaccact tgacccatgt actgcttctg
    10681 taccatgcaa tatatatgct gatgttccag tagatgaaag caatgatgaa atatatcctg
    10741 atacatgtcc tggtttacca ataccagtca catgtacacg tccgtgattt ttttcagctt
    10801 caagaattaa ttcgcatgct ttatttatag atgtctcatc tattgaggca ataaattctg
    10861 acaattcatt agatatatta tctaaaaatt cagataatgt attttccata agatgtatcc
    10921 tccttgaaat catagtaact atgactatac ttttatataa tttagtttaa ataggtttta
    10981 taaattgtaa aatattatgt aatatcgaac caactacgtt gtaatcaata ttagggaaag
    11041 ttgctccttc tataccaaga gtcccataaa ctggatatag tataactggt aaaaatgcaa
    11101 gtaataaccc aacaacaaat gacccagcaa tagcccctct ccatcctcct gaagtattgc
    11161 caaatattgc agctgtacct cctgagaaga aacatatgtg agcagctgga ataattacta
    11221 caggaaatat actaggaaat gatgccataa tagcaattgc taatagacca gcagcatatg
    11281 ctgatataaa cccaataata actgcatttg gtgcatatgg aaatactgtt ggaacatcta
    11341 gcgcaggacg tgaacctgga atatactttt ctgaaatgat tacaaatgct gcagttattt
    11401 cagctaagaa catacgaaca cctgacatca atattgacat acctgccaca aatgtaaatg
    11461 cctctataag cggaaaaacc aaccaatgtg ttgaaccagc aatttcttga gtaaatgctt
    11521 gaccagcttt taatgttgca atatagaata agattaacat aactatggat agacccatta
    11581 agaagtctct gaatattgat aaccacttag gaaattctat agtctctgtt gtatcatctt
    11641 tatgttttga aaataaacgc ccaatataac ctgataaacc ataaccaatc atgttaaagt
    11701 gaccaatagc ttgttcgtcg ccacctgtta attcacgcat aaatggttga cagaattgag
    11761 gtagtgcagc agacataaac cctaagatag ttccacctat taaaatagtg attgtattat
    11821 caaatccatg tgctttcatg attaaaacta atacacaaga aaagaataaa ctatgacctg
    11881 ttgtaaagaa aatattctta aactttgtaa tacgtgcaaa tactaaattt aatatgaatc
    11941 caagaattaa tgtacatgaa actgcaaaac catatgtacc ttgtgcaagt gctgtagctg
    12001 cttctggtga agctataaca ccagtaattc caaagccatg ttggaacagt ttattgaaat
    12061 tttgaagtgc tcctgtcata gcagaggcac caataccaaa tatcaaaaaa ccgataagtg
    12121 tttttgaaga ccctgtaaat acttcaacgg ctgatttctt ttgaagaatc aatcctatac
    12181 atgcaactac gccaagcaaa acagcaggtg tactcagcaa actaataata aactccataa
    12241 atattcctcc ttatcatatt aaatttatcc ctcttttgaa gcaaggaatt tttctagtgc
    12301 tgtctttatt tcattacggt caacaatatt gtgaatccca attatatcaa acttcaaatt
    12361 tttatttttt aattcttcag caacatcaat taatgtttct acagcatctc cattgaatcc
    12421 atttagtgaa tccaatgaac catgttctac ttcaattgga aagttatttt ccttaataat
    12481 ttgttgagtc tttattttta acattaaact tgagccaact cctgctctac atgcgattaa
    12541 aattttatac ataattaaat cctcctttat aattcgtgtg tttttataaa atcaataatt
    12601 tctttagcct ctttagcact atctaaaacc ttaaaaaact catcttcttc caatagttca
    12661 actagctcag acatagcacg taaatggcta ttattgtcta ttgcacttag acaaaataca
    12721 tattttacag ggtcgttttc gttattccca aactcaatag gactatctaa agtagcaatg
    12781 cctattgcaa tctcttttga cccagcttct ggtctagcat gtggaagtgc aacatgtttt
    12841 gtaattacta tgtatggtcc agatgctttt gctgagttaa tcatagcatc tacataccct
    12901 tcagttactt tgttattttc aactaataca gaagctgact gtctaatagc ttcctcccaa
    12961 ttcttagctt ttacctttat ttttactagt gtttcattag taatctcact tagcataggc
    13021 ccctctcctt ccttagatgt aaaattctct atctgtgtaa aataagctaa tagctcactt
    13081 gaaagaatac tttcagaggt tacatttgca tattttttta ttatatccat aacctcatct
    13141 attttaggtt gtcttaaata aatatcacct aattgaatat acacttcacg tgtaatctta
    13201 tatttttctt ttgtggtcat aacagggctt actttaatta ctggtacatc tgtttttaaa
    13261 ccctctgcgt tataattagt agtaaatacg atatctacag gttcacttat attttctaat
    13321 ccaactgatt ccgacattgg tataaagtgt aagtcaggaa ataagtttgt aagttctgca
    13381 tgtaaaatag ctgaactacc aacgccattt gaacaaacta ttaatgctat tctttttcta
    13441 aaaccatcaa attctttttt atttgaaaaa agtgttgcaa agtgcattgt aagatatgct
    13501 aactcttctt cctgaatttc ttctccaaat aatccgcaaa actctttcat tgcattactt
    13561 acaattctat aaactaattt atattcttct tttacttttt cacaaatcgg attatagata
    13621 ggtaatttaa ataaaagtct atagtaggca ggtctaaaat gagaatataa ttgtttaaat
    13681 attttttctt ggcttatata gtaaactccg cttaaatatc caaactttgt catcatttta
    13741 tttacaattt ttgaaattac atccttatct tctgtatctt cttcataatt tcctaccgat
    13801 atacctaaaa tccaagcact aatatacatt atattataag gctttatctt atcctcactc
    13861 ccatatactt ctaataattc cttagcaaat ttatactcct tcattgaact cataactgaa
    13921 atattaggaa tatctacatt ttcctgagta actattctag ttgaatacat ccttgctttt
    13981 agaaagataa atatatatat aaattctatt aatctatctt caacaaaagt aatttcatat
    14041 ttttttatta gctttaatat aattttttta gcctcttcaa aactatctaa attatattct
    14101 ttaataaaaa tatcaaatac tcttgaactt ttctcattag acaaagtttc tataatgttt
    14161 ttaataagca ctctcctaat ttccatctca ttgccaacta tgtaatatcc atttatacga
    14221 ttgttcttaa ctttaatgtt cttcttttca agctctggta tcaaatcctt gaaatcaaga
    14281 tttacagtag acctacttac ttttatagaa tttataaaat gattaattga aatatcctcc
    14341 atgttaataa aaagcattaa atacatatat aaaagtcttt ctgtcttact aaaataataa
    14401 gtattcttag aatagttttt ttctaaaatt tctttaattg ctttttttgt ttcttttcta
    14461 acgataatat ctttatcagc tcttaaacat ataagtggta cattttttac tttaagcatg
    14521 tcattgattt tatttattct ataagtaatt tgtctctttg atgaattaga ctcctcttgt
    14581 aatccattag ttgtaatcaa tgtgctattt aataaaatct ggagaattga tacaatttct
    14641 ttgtccacta ccattaaccc ctactttctt attaagatta gtcttcatat tatcattgga
    14701 ttctttcatc acctccacaa tacttatttt atttgagaat tttatcgttt tcaatttcat
    14761 ttaagtataa cttttgtttt agattgagac aaaaattaaa cttatctaaa atagctacta
    14821 tattacactt atagatttta taaataaaaa agggttcctt atgtaaagaa accaaaaaaa
    14881 atttatttaa agaatcaaag cgatactaat tatgcataaa ttaccataaa taaaaggcac
    14941 attaatttaa aataaaatta atgtgcctta tttataattc taatatatta aatttatttt
    15001 ttaacttgta gtttaatatc ctttttcttc aattaattca tataaataaa gtatttaata
    15061 ataaatgttc cttatgactt taatatttta aaccaagaaa gttaaagttt ctctcatata
    15121 ataaattgac acttatctat ttcattcttt taagtgtaca ataagtcttc ttctagcagt
    15181 aagagtaagt acttcctcta cttatcacaa actataattt ttatctcatt ggtatatatc
    15241 cacgatactg tgagtatgca tccatagttg ctatatcacc taagaatact gatgcgatat
    15301 tgaattgtgg ttttaaatat gggaactcct cttcttgtgc ccattctggt tttttaataa
    15361 acgactttgt ctcttcaacc acagctttat accattcctc ttccccttca aaccatagtt
    15421 ctgatacacg gtcaaaagca gttgctccat aattaatcat tattttacta ctgacaaaac
    15481 gattaacata gcaacagttt gtaaagtatg gcactacctc atcatagaac catttttctc
    15541 cttcttcttt agagatacca tctggatact taatcataaa ttgccaacga tagtttggtc
    15601 catcttgtac agtacgtcct tttcctctaa agtcttcttc ccagtttatt ggaacaaaag
    15661 caaatataaa tggtgggcat ccattatctc cacctactgc acgtcctgca tctccacttt
    15721 ctgcattttc atgaaccctt ttattttcta catctggtat acacccttgc caacgtagaa
    15781 catccatagg catatattct gtcataattc tatttgccat ctcaggcata tgttcatcta
    15841 caagccaata atgttctgtt agttgcatct tacgtgcacc aaaacgctca ccttcatttg
    15901 gtgtaggata tgcttgataa aaggcatatt tagtacaata tggtccaaaa gtgctaatac
    15961 tatctggaat atggtgacga tataaccagt ccattaactt aggtctatat tcttccttgg
    16021 caagtcctac atatattaaa cttctcatta ttttaaattc aaaacccata gccattctcc
    16081 tataatcaaa gtatattcac atgctttcaa tttccctttt tcttatcttt actcaaaata
    16141 tatattgtaa acaaatctac acctgcaccc acgtaccata ctcctactgc catagctaca
    16201 gcaatttgaa tacaaatatc ttgtaaatta ataatatttt cacctgtcat aatagttaga
    16261 cctatagccc aaccacaaag ccatgatggt aggaaaatta ttttttcaaa taaggatgca
    16321 attacaactg caaaaaaacc taatatacta agtgttaaaa ataattctag gttttgattg
    16381 aaattcatat atcccataat taaaatggct aacactgccc ataaatctcc acaccaaaaa
    16441 ccaaacatta tttttaatcc atctttttgt ttattaccat tagttacata taatcctgca
    16501 cagattagtg ctacagctcc agtttttatt cctatataag gtgctaatac tgcccataaa
    16561 ggaggtagta aagcaatccc catagacagt gttaatattt cttttttctt tctatccatt
    16621 tcctatattg taattagtag cttccctagc ttgccttatc tccaatagct taattgctat
    16681 ttgatttaca atcatagata ctgcaaaata acttaagtat aatggtataa atataacaat
    16741 aaatgctgga gttaatccaa tcttgtaata tgtaagtacc aaaaaaataa ctgctaaaat
    16801 aatttcaatt tgtttaaaac ttggcttttc attcatacaa taagcctcct ataacatcta
    16861 acatccctta aaaaagagtc ttagtatttt aattattatc ctaatgaaac tccagcttgc
    16921 ttttctttag ttaatggctc tataaaatta taagatgttt ttctttcttt aaattcttgt
    16981 gttttacgaa cttctgcata atgaccttcc attttcttaa tatcatcacc atgtataaac
    17041 ttacctggta aagtatcatg agcatgacct aattgctctt ctggaaaact aaatatagtt
    17101 tttccactta tagtatctaa ctctccaact ataccacata gagcacaaat tgccttttta
    17161 gtacctgact caaggtagaa taatctattg tggcaatgtg gacatacacc ttcttctcct
    17221 tgatatgaag ctttttcaaa atcttttgct gcttcaacta tatttaaacc aatttgatga
    17281 acttgaacaa gccttgtatc atccattact aattcctttg cccatgggaa ccaagcatta
    17341 tctataactt tccacattgg tatgagagct agcatagcat gttcacattg aactcttgta
    17401 ccccagtcag aacctcctat tcccataaat gatattactt tatcattaag cattcttgag
    17461 tctggaattt ttcctcctat agcttctgca acttttgttc ctataatgtt atttcctcta
    17521 tctgctctgg gtccaaaacg gtccattata gtatggaata atcctgatgc cccttcttca
    17581 aaaatagggt ctgaaactac tataccatct gcatctttca ttttgtcaag caaccattca
    17641 aaatcatctt ttaatacaca catactacct ttcccggata ataaagtttt aacgcacgca
    17701 caacatccag tacaatgttt aatgttaata gatgacattt gaataaattc tacttcagcc
    17761 cctgcttctt tggcaccttt aagtgcaact ttacacattg tgtcattatt tccatttttt
    17821 gttccaaaag aaatacctag tattttcatt ttcaactctc cctctttagt atttatttaa
    17881 tcttctttca tttttaatat atagaatcca tcatctaaag catctatgat gatgtagcct
    17941 ctatcatcaa cgataagatc ttctgttact gccaagcgtg gtcctgggaa tcctgggaaa
    18001 taagattctt ctggtgtttt atttggattt ggtggtataa aatatgctaa ctctttgata
    18061 taatatgggt ctgatacatc ataaaccctt agccctgcat ggaaataaca gcaatatact
    18121 ctatctcctc tttgctctaa ccatggctta ttatccattg gttcatgaag attatgtgga
    18181 ccaaatggcc ctgcttttcc taatcctgca acattaaagt taggataagg gaaatctttt
    18241 ggaacttcag gatatgggaa ttgagcaatt aatgttggtt ttgttgggtc actaacatca
    18301 accatatgta tattattcat agcttgaaca tctgtaatgt tatctggttt aaagaactgg
    18361 aatctttctc cctcattttg aacaacgact aaatctcttc ctggcaatgg taatgctgta
    18421 tgagttcttg cacctgcaag tctactagaa aatgcaggca taaatggcaa ttcacctaag
    18481 catcttggtc ttgttaaatc ttcaacatct aatacaacta aaccagctcc tccataacca
    18541 caatatgctt ttccgtctct tacaaatgga ggtccatgaa gccatccttt atccataaat
    18601 tctgggcaat gaggtgctcc tgcatcaaaa gttctatttg gatatccatc tgcatattgg
    18661 tctggtctcc accatttacc tatttccact ggattattag gatttattat atctatgacc
    18721 ctataaatca gaccttcaaa gccaacacaa tcacttgata aatgtacata tcttccacca
    18781 ttgtacatga atctatgaac acccattaca tgctttaagc cacaatccca atatcctaaa
    18841 aacttaggat ttaaagggtc ttcttttaaa ctgtatattc taattcctgc ttcacactta
    18901 atatttgcta atttagcttg gtcaacaagt gctcctggtc cacttccaca actcattgct
    18961 actatcatta aatcatctgc tatttgaatt tttggagttg ttgttgtagg atactcttta
    19021 gggtctaaca tttgaaaatg ttttataaat tgtggattat aagggtctgt aatatcgcta
    19081 atcattactc catttttttt atttcctcca aaacagcatc catataaata gtatttttca
    19141 tctcttttgt acagagccat ttgaaacatt ccacaagttc catctaagtt attaaaggaa
    19201 caaacttcaa gatttttaat atatccgtta tttccgttgc cttttgcata aaatttatct
    19261 tccatttttt ctcccttctt atttaaagta ttatcaattg atatactttc attttatgag
    19321 acaaacttac ttaaatccaa tatcgttttc attggaatat ataagttatt cttattaata
    19381 aatttataaa atctaatgta aagatatact taaaacatat atttttatac aaatattttc
    19441 taatattctt taaaagtaaa ttttcttata ctataataag ctttaattat agataaataa
    19501 ggtttacaaa caatcaagtt taaatagggg tgattatttg aatactaaac aattagaata
    19561 ttttatatct gtagcagaaa atctaagttt taccaaaaca gcagaaaaat tttatatttc
    19621 tcaaactgct gttacacagc aaataaaagc tttagaagaa caaataaatg taactctatt
    19681 tacaagaagt aaacgtcatg ttgaactaac accagccgga aaagtttttt tatctgaggc
    19741 acgtactata ataaaaaata tcaatgatgc tattgcaaaa acacaacaat ttgcacatgg
    19801 tttttttgga actttgagca ttggaacctt aataggatat gaaaaaaaca aacttcaaca
    19861 atacttaaaa gaattttcta atacataccc taatatatct atggatattt gtactaatga
    19921 aataaccgaa cttttaaact tagtaaaaaa taattctatg gacctcgctt ttgttattaa
    19981 tccagaaaat caaccattaa aagattttga atataaaact gtagaaagat attctttggt
    20041 agctctttta cctcctggtc atccacttta caatgaggat tctatcgatt taattgaatt
    20101 acaacatgat aaatttattt ttgtaaaaga aacaggggat gagtatggac aaaagtcaat
    20161 gatacaaaat agatatcgtg aagcggggtt tgtacctaat gtggtacaac gttcaaataa
    20221 tcttaatact attgaatcat tggtatcttc taacatggga atatccattt taccttcatt
    20281 ttgtgttaca gatacaatga tagaacgtga tattgcaata gtacctataa aagaagtaga
    20341 aaatagaatt gaagttgtgg ttgtatggaa taaaaaaaat acaaatccag cattagaaaa
    20401 gttcatttct ataatataaa attaatcaat attaactata aaaatagcat taaccatttt
    20461 tatatggtta atgctatttt ctactatttt attatctaac ttttaattta atatttataa
    20521 tcgttaaaaa taactctgtt taacaaatat aagcaagtca aaagtgtgtc taaaaaagat
    20581 aaaaatttta ttatatacaa atgtattatc tcaatatatc tattttttca ttgttcatca
    20641 gtctaagtac atgacctgtg cttactaaag aattatcccc ataagttgta tgagctaaca
    20701 ccgaactagc aaccccaaac tcaactatat cttcactctt catattttcc aaatatgaat
    20761 atataattcc tgccacatat ccatccccag caccaactct gtcatatatt tctaacttat
    20821 actccctact ttcaaaataa ccatcatcat ttgatatata tccctttata aatctattat
    20881 tcatatcatc aaatcttctc atagttccag ctacaatatc tatatcatac tcttttttaa
    20941 tcaattctga actagatttt atatttagac tatctatatt aagtatctta tttatatctc
    21001 tataactagc aaacagccca tgacaatatg gtagtatttt cttataatca tttactaaat
    21061 catcataagt cctttctgga tttaatgatt gtctaaaatt aaaatcaaag aatactttta
    21121 tccccttttc ataagatttt ctagctagtt ctaaagcaat ctttttaact gaatctgtaa
    21181 gttgcatagc aataccacaa atatggacta tatccatttc ttctaaacat ttatcaatat
    21241 cataatcttg taatttactc tcacaaaatg aactatttaa cctattcaaa taagtcactt
    21301 cagaaggtct ttctccatac ccattttcaa gaaaatacac tcctatatga ttccctccat
    21361 atgtgataaa gtcatctttt actccaagct ttcttatatt tgcacttgat gctttaccta
    21421 cattattatt aggcaacttt gtcaacatat aggtattgta tccaaagttt ttaagtccag
    21481 ataatatatt taatcccgtg cctgtaatta tataatttag ttcattggtt tgtgttaaga
    21541 acttgtagtc aggtactgaa agtctcatca ttatttcacc aaaagctaat atattcataa
    21601 atctatccca ataattcttt cattatttta taaagtactc ctatatcttc cactttcgta
    21661 tcacctgttt ctttatcaat tattgatgta taaacatgag gtataacttt ttctacacca
    21721 gcatcaagtg caatttgaac tatctctttg aagttatcta agtctatacc ccctgttggt
    21781 tctaaataaa aattatgctt tgcacaagct tttgcaactt ctatatattc atcctttgtt
    21841 ttaagccctc ccattggaaa aaacttaatt gagcttcctc ccatatcttt catcatagct
    21901 attgctgttt ctataggaac tataccatct ttttcttttg aacttaatgg acctgtggat
    21961 atttttacaa atcctggttt accagttgga gaaactaatc catttattat actatcattt
    22021 tgaccaagca atgctctaga tgtagcgaca cctgtaaaca cttgatttat atgttgtggc
    22081 tgaagttctt tagaaatctg agataccata tttgactgat ttgggtctcc agctccaaga
    22141 cccacagata ttgcattatc tatttccttt gagtattttt tcatatcttc aatagctgct
    22201 tctacagtgc tataattctt tgatagtact cctactagta catgtccatc acaggcatca
    22261 tatacttctt tagcattttt tatgcttcct gcaagaacat ttaaacaaac tctattttta
    22321 taatattgtg gtatacaatt catatttatc ccctccattg gtaaaattca atttattaaa
    22381 tcattataat gtcacttact ctacactcta actttctact atatttttta tcctattata
    22441 aatattatct aaatcacttc cagttacact tcttatatca atctcaatct tgccttcatt
    22501 agccttatag tctctagtgt atatagctat ctctccactt ctaagttcat ttataatttg
    22561 ttgtgttgac ttatttatta tatcttcatt aaagttaatt tctccacgaa gtatttctct
    22621 acctgctgaa tctctagtta tactagcact cactcccttt atagtattta tcttgtctat
    22681 aaatggattt agcttgtcct ccatttcttt taaagttact ttatcattac ttatatatct
    22741 ctcaattgca catgttagac ctacaatatt ttcttttcct attttcatag ctcttcctat
    22801 accctttgat tgaagcttta cattatctat gtattttttc ttacctatta ctaaccccga
    22861 gctaggacct tctatagcct tagcaccact gtatatcact aggtctgctc ccaattcata
    22921 atatacattt aaatcttctt ctgctgctgc atctactatc aaaggtaaat tatattcttt
    22981 agcaacttgt actgcatcta atacacttag catactcttt tgaacacaat gatgagattt
    23041 aatatacata attgctgctg tattttcatt tatctctctt attatatgtt ccttgttaca
    23101 catattagca tagccggcct caacaacttc tcctcctcca agtcttatca ttacttctac
    23161 tggaactcca taatcaacat tatgcccctt tggaattatt atttcccttt taacttgttt
    23221 cttaggatta tttacattgt aaactagact catatcatct tttgctatca ttgctcccac
    23281 actctgtgca atcccagcag atgcactaga aactattagt gcactttcac accctaataa
    23341 atttgctata tattcacctg ttttatttac aagttcttct attataagga aatttttaca
    23401 cccttcacct attgcttcaa taacttcctt atctactgtt gatactccta gtatagtcat
    23461 tttgcctgaa gcatttataa cacgtcttac agagtatttt tcaaatatac tactcataca
    23521 atagtttctc ccttctactc attctcttct atagagttgc ctatatttaa atattctcca
    23581 ttgactacta ctgctcttgg ctttatagac gtacttgtga ttactgactt attcaaagaa
    23641 tcttgaagtt ctttttcttc attaaccaca tcaaatatag ttaaatcagc atcatatcct
    23701 tcttttatta aacctttatt ttttaaactt attgcatctg ctgcattttt agtaacttta
    23761 tctattatat cttcaagtga atagcccata tatataaact tttccattgt tgtagataga
    23821 ttatacactg gaccatttat tctattttta atatatatat ctgtacttat agtgtctgga
    23881 aaaattcctg catccttaga tttcattgca atatccatac taaaactttc ggttccatga
    23941 cctacatcaa gaattatacc tctttcttta gcttctatga tttccttttt aacctcattg
    24001 cctctaagta ttccatttgg ctttccatta tatatatggg ttaatatatc tcctttttcc
    24061 atataatcaa atatatcctc tatcgttgga ggagaactcc caaagtgaac catcataggt
    24121 agattaagtt cattttttat tcttttagct acttttaaag gttcaacatc atttgaaatt
    24181 acaacacttt tactcattct agctttgatt ccaacaacaa aatctttgta ttttctaact
    24241 gcatttttaa gttcatattc atcaatattc atcatatttg aaagttcatc ttgagatgtt
    24301 attccctgct tagcaatatt tattaaagca tatacattgg tcttatactt tttagtatct
    24361 tcataaaatt cacctatatc taaagctcct gttgttcctg catctactac agtagtaact
    24421 ccacttttta ttccaacctc atctggataa tccttataaa ggtctagtct ttcgtagcag
    24481 tgtgtatgta tatctatcca acccgcacta ataaatttct ctccatctaa gtttataatt
    24541 tgttttgcct gatacttaga atcatctata tgatttttta cttctattat tttatcgtct
    24601 aatatagcta tatcaattat acttttatct actgtttttc cacattttat taatatgtct
    24661 atcttcactt tactctccct ctaaaataat cttaaattta ctccaaggtt caataaagtc
    24721 taaaagtatt atttcgtctt cctttattct acccacctta ttttttcttt catctgtaca
    24781 atcttgaagt atcaactgta attccccttt atactttcca aagtcatcat taccaatcac
    24841 tacatctcct cttttaaaga tgttcttatt atcatgttta gggaaatttt ctttagcata
    24901 tttttttctt acttctgtag atcttgctac ctgattagtt atatctcctc ttctaaagtg
    24961 ttgctcattt accattatta tcttttctac ttcagaagtt ttttctttag ctactacatt
    25021 aaatacaact tggtattcat ttacttcaga cattcttttt aattcatctt cacttgcata
    25081 tgcatttcct acaattacat catcaatcaa tcctgttgcg aataagtgct tagttgctgt
    25141 agcaatatct aagtttctat gcatttcaag cgtacacagt ccatcattta tattccaagg
    25201 tccgattgtt gcgtattttg aattgacaaa agcagcagtt cttattccat actttttaaa
    25261 tctatttgag catcttacaa aaaaatcata tggcaagcct gtaccccttt gaggataaaa
    25321 attgtgacaa ccatatatat tatttacatt tggcttgtaa gtaattatat tatccaagta
    25381 tgctacatca ttactcatat ttagttccac ttttaaatca tatggattga aagaaatcat
    25441 agcttcttta cttccatcat atccatagtc aagccttatt ccactagcat ttaactcact
    25501 aaagaatgtt aaatcatcat aagatatttg taatatatca aatatgtttg gagctatatc
    25561 aaggattact tcaaatccta attctcttgc ataggttata atctctttaa aatgtttttt
    25621 aacttcttcc ttaggtcttg taattgaaag catgcacata aatattcttt taaatccgta
    25681 ttttgaaacc atttttatat atgccttatc atcttccatg ttactatgct ctggatatac
    25741 tgatattcct aatcttcttt ccatctttct cctcctcaaa ttacattatt taaaatatat
    25801 aaaattaaag gcaaaggtca ttcctcctac cttcaccctt aataacttat aagctttttc
    25861 tatattttat atagtacaaa acctctatat ctatgtattt ttataaattt tcactcattt
    25921 cttcttgttc tctttgtaat tgttgttttt caaaaacttt gaagaatgga taataaacag
    25981 caaatgatat cacaaagttg attaatacta agatacctgc tagtatactc cagttagtac
    26041 tcattactgc tgctattggt gctggcattg caaatggtaa tcttgctacc atcataggta
    26101 taacccctgt aatagtaaga acatatgata gaattgtcat tattataggt ccaattataa
    26161 atggtatccc tagtattgga ttcataacta ttggtgctcc aaatattata ggttcattta
    26221 tgttgaataa ccctggtaaa aatcctaatc tacctaaact ttttagatat tgtgacttag
    26281 aaaacataaa cattacaact aatgcaagag tagcccctgc tccccctatc catacatacc
    26341 actgtaaaaa ttgttctgta aatatgtttg gcattgcatg agctgatact ccttctgtga
    26401 atgcagttat attttctgct atagacatgt cccatatagg tcttattact ggccccatta
    26461 tagctggacc atgtatccca agtacccaga ataaagttat taggaatact gtcagtagcc
    26521 caccacctaa actatttcct gataagaatc cttttaaagg tgataacata gcgcttagtg
    26581 caacacttat atcaaatcct aaaatatgtc ttattaccca gaataacatt aaaattactg
    26641 ctgtcggtaa taatgcagta aatgaatttg aaacctctac tggaactcct gctggcatct
    26701 taattgtaat attcttttcc ttcataaaac gatatatttc aactgtaatt aatgatgtta
    26761 cgatagctcc aaataatgat ggcgaattaa gttttgccat atccatccat ctaccagctt
    26821 ctataactcc acctactggt tcaactactt gagttggaac tattgtagaa actaaaaatg
    26881 ccataactgc aagcatacca acacctgttg tatctaaatc gtagctttta gcaagtgatg
    26941 atgctatccc aaaagtagca tatagagata aaaatcctac agtatatcta aatggtatat
    27001 ctaatgttgc tttaaatgga gctataaaat ccatataagc atcaataggt atgtttaata
    27061 atattgtgaa aaatgacccc actattgtta gtggtaatgt tgctattata cctgctctta
    27121 cagctctcat atgtctctga ttacttatct tcgctgctac aggcataatc ttgcgctcta
    27181 aaaaacttgc gaatttttcc atagttatcc ccctgtatta ttgatattat cctttattta
    27241 taatgcaata acgatttcat aacataaact aatttttatg taattgataa tatcacttat
    27301 ttattaaaaa tattataaca ttataatgtt tggttgtaaa cattataatg ttataatatt
    27361 tttcgttttt acaactaaac aaaaatcctg agcatattat catttcaata aactcaggat
    27421 tcttattata tttcgtattt aattacgtag ttttgtactt ctgtattata tcttgcaaat
    27481 gatagctcaa ctatattatc attctcatca taggtctttc tttttcttcc taataatatg
    27541 tctttagcta gatttagagc ctttgatacc tctagttctg attcttctat aaaaaattca
    27601 tcttcaaatc tagttatatt tatatttctc ctatataagt acatatataa agaactttca
    27661 ttattaaaac tttcaacagt tagattttca tcaaaaggaa tataatgagt aaaaaatata
    27721 tatggcttac tatctaagta atacattcta gtaatcttgc tacatttttc tccaaatata
    27781 ctaaatactt gtgaatttgt atcatttatt attttttcaa ttgaaatagt ctttttagat
    27841 aacttatgac ctttagataa aagtatactt gaaaaagact ctgcttttga tagcttatta
    27901 aaaagactat tacttattac ttttgtccct tttccacttt ttttctctac atacccttct
    27961 gattctaata tctcaatagc ttttctaata gtaattttac tgactccaaa ttcttgctct
    28021 aattctcttt ctgttggaat attttcatca attttatatt cgttatttaa tattttttgc
    28081 tttaatatat ctacaacttg tatatataat ggttgatttc ttaacatgat tcacctctta
    28141 aattatatgt tataatatta taacatataa tcttatatta ttaataataa atatttatta
    28201 actttaaact aaatataaaa agagtcctca aaataatcct aatgtattac tcactaaata
    28261 ttgaatcaat aatctaacaa ttagtgtgct acacataatg tatcttttaa gaactctctt
    28321 aatttattct ctttaatttt tatttatctt gtaatttcaa atgtaaatca acgatttctt
    28381 cagctaactg ttgaaaattc ataccattca ttaggtggtc ctgtgcatgt ataagtatga
    28441 cacttatttc agtcctgttt ccactagctt cgttttgtat taattctgtt tgatatctat
    28501 gtgctttatt tataacttcc ttagactctt ttaataattc ttttgctttt tctatatttc
    28561 cattcttagc ctcttttatt gcttcaaaag ctaacccttt accttcacct gcataaccta
    28621 ttatattaaa agatatttct ataatctttt catccatcct ttgattctcc caatttatat
    28681 attaaaaata cattataatt tatattactt agtgttgtta agttctatcg ctctatttaa
    28741 aacagcttct ccattaactg ttccatagtg catcatattt ataacctcta ctggtatatt
    28801 atatggctta gcaatttctt gagccttagg taatacatat ctaacttgtg gtcctagtaa
    28861 taatacatca catttttcta tttcattttg tatagttgat tctggtattg cccaaatttg
    28921 cgactctata ccattttctt tagctgcact ttccatttta gtaactaata aacttgtaga
    28981 cattcctgct gaacaggcca acattatttt tatcatatat tttcctccaa atttttatta
    29041 acaactatat aaacattata atgttataat attttattta attctacctt aaatgcaata
    29101 tactttcaat acttttttgt tattttaata ttattaagtg tcaaattagc aaaaaccgta
    29161 tcatttattt atgatacggt tctccattat ttatcctata agccctataa atctgttcta
    29221 acaatatcaa tctcatcatc tgatgaggaa aagtcatctt agaaaaggat aacctataat
    29281 cagcccttcc taaaacctca tcagaaagcc ctaaagaacc tcctattata aaacagagac
    29341 tactattacc tctaactgct aaatcactca tagtcttagc aagttcttca gaggataaac
    29401 ccttaccatc aatagccaag actataacat aactattatg ctttatcttc cctaaaattt
    29461 tctttccttc tttgtctttt ataatttcca tttccttaac actcaaattc tctggagctt
    29521 tttcatcatc caactctata atttctaact tacaatactt agaaagcctt tttttgaact
    29581 catcaatacc taattttaaa tatttttctt taattttacc tactactact atacttatat
    29641 tcatatattt ctcctaaact taattttatt acaaatctat gcattactag aatttacaag
    29701 ctcttataaa attatatctc tttttcttga tttgcatatt ctacaaactc ttcaaaaggt
    29761 attgctttgc tataataata tccttgatat atttcacatc ctaaaccata taacttatcc
    29821 ctttggtcta tattttcaac atactcaaca actatatcaa aatctaaatt ttttgaaaga
    29881 tttacaatag tcattataat ttcactactt cttttatttg taagtatctc tttaactaat
    29941 gaaccatcca atttaactat atcaaagtta ttattttgaa gatatataag agagctatgc
    30001 cccatcccaa aatcatccat aattaacttt attcccaagt tatgtatcgc attgatacgt
    30061 tcaataatta tttgtgaacc tgataatgca atttgctctg ttatttctat acctaacata
    30121 ttaggattta tatcattact actaatgata ttttttattt gctccggtaa cttagggtca
    30181 tcaagttggt ctggagatat atttacagag aacttaacag gatttctcaa tagcttttca
    30241 ctcttcttta aatcaataca tgctttatta ataatatact ctccaagctc atctaagaac
    30301 ccttcttctt tagccaaaat tataactagt ggtggataaa tgaaccctcc tattgaatgt
    30361 ttccatctaa gtaatccctc tgctcccaca acatttccat tataattgac ttgtggttga
    30421 taaaaaagtt ctatttctcc tcttttcata gcaaacttca agtctgatgc caacattttt
    30481 gaaattgaac ctattttacc attatggttt agaagattag gctgttcacc tgttaattca
    30541 taccttttta ataagtttgt taaattttct atattattct taaacatata tgtatatcta
    30601 ttttgcgaca tttttataaa cggaatataa atcataacac caacacataa attaaatact
    30661 tgcaacaaac tacctcttat tgaacctgta gacatatatc cacttaaaaa tataggtgag
    30721 gtccattcta cagctgaaac tgtacatggt acaatacctg tagacatagc cacataactt
    30781 gtaatggtta agattatagg agtaattaca aaaggtacaa acataatata gttaaaaaca
    30841 attggtatcc cgaaaactag catctcattg atattaaaaa gagctggtat tgaagcaatt
    30901 ttagctagct ttcttacatt tatacgtttt tcactaagaa aaattgcaat tactaaacat
    30961 agtaaagagc cacatcctcc caataaaacc attgtatcaa aaaaggtctt agtaaaaatt
    31021 tctgttggta attgattatt attaactaaa tttatgttaa ttgccatact attttcaaat
    31081 aaattttttg cgacggtatc taatacatta ctaccatgaa tcccaaaaaa ccacataaag
    31141 tgcattaaaa aaataaacaa cagagcactc ataaggtttg ttcccatttt attaaaaaca
    31201 tttgaaaata aattataaaa tatatcttga aagtttgaac tgccaattag acttatcatt
    31261 atcactctaa aaatagaaaa caaaaatact actattatga aaggaactat agccgaaact
    31321 accatattaa agtctgcatc agccccttct gtatgaaact ttacacttgt aacaaaagat
    31381 tctgtaagtt ttacaaacaa tacagaagat gtcatagaaa caattataga tgtaaataac
    31441 cactttgtct taaatatttc tatataagaa ttaagctcat taccatgtga aaatactaaa
    31501 aaagagcaca ttgcaactat aggaacaagt actgtatact tgctcccata tatttttcca
    31561 taactatagc ttattgttaa taatattatt aatgaaataa ttcctaaagt agaatcattt
    31621 ataaagttaa gaatatttgt aacctctcca ttaaacaagc ctgataaata ttcttgataa
    31681 gcctttattg gaagattcaa aattacaaga gccgttgaac cagtcataat agcaggtatt
    31741 gctaaaatca taccctgctt tatagagtat aaaattttat tatcctcaac attttcaaaa
    31801 tttctcttta gcaaagttat tcacctctac ttcatctcat aaacattaga aacatcattt
    31861 cgtgatagta catctagttt tacatcttgt ccaactacta tatcatttga tgctaatact
    31921 ccttttgaag tctcatatgc taactcagga aaattatttt ctttacttaa atgtgctaat
    31981 aatatagatt ctgtaccttc attaataagt tcaacgcaga aattagctgc atcttcattg
    32041 gataaatgac cagtacttga cattactctt ttctttaaag catatgtata tgaacccatc
    32101 ataagcatat tagggtcata atttgattcc aatactacta atttagattt atatagatgt
    32161 ttttttatat tttgagttat acatcctata tcagtagcta tagacatttt ttcatcactc
    32221 tctgtataaa aattatatcc aactggatca gacgcatcat gttctattga aaaaggtctc
    32281 actatgatat cacctaatga gtaggtttta tcattttcaa atactttcat atttttatct
    32341 ttgatgtcac ctaatttgtc cttcatagaa caccatgttt ttatattagc aaatactggt
    32401 atatcgaact ttctggataa tatacctgct ccttttatat ggtcaacatg ctcatgtgtt
    32461 ataaatattc cttttaattt atctgcatct acaccaatgt ctttaagacc tgtagttatt
    32521 ctcttgccac ttaatcctgc atctactagt atattagtat ttttataccc tatatagtgg
    32581 caattcccac tactaccact ccctactgaa caatacttta gcattccttc acctcttttt
    32641 ctgccttata aattatatta taccaaaaaa acagagtatt aaataaaatt taatactctg
    32701 cacaaaattt acttacattc actatttact tacattcact tataatctta tttatatcta
    32761 cacctttact attccatagt tccacaaaag ctcttccatt agcattttta tgcttatatt
    32821 tattatagta ttcatttaaa gtctcaaaga atactttatc tccaacttct tttcttattt
    32881 cattaaatgc tattgcgcct tttgtataaa cattcaagct gtattcagta gaatttttat
    32941 actcatttgc tggcttaaat atattttcac tcaaataact ttttgtctgt atctccatag
    33001 tttttataag cttgtttgcc atatctttac catacttttg ttcaaaataa actattgtag
    33061 aatattcagt aagtgcttca tctaaccagg gttcacttat ttcatcattt ccaacagcag
    33121 aataccacca ttgatgtgct gtctcatggg caataacata ttctagtaaa aattcatttt
    33181 tttcattata taaactttgg tctatcataa caagcatagg gtattccatc ccccctataa
    33241 aaaagtcact tgctacaaca gaaaattctt tgtaaggata ctttccaaat aattcactaa
    33301 atatatttat tgaatctttt gccacttcag ttgctttttt agaaagcttt ttatttaaat
    33361 tatatgtatt gatagctact ccctttgaat ctactttgtt tacatcaaat ttactactta
    33421 gtataaatgc aaaatctcta acgttttcag cttctatttc atatagcatt ttcttattat
    33481 catgtttatc atcaataagt tttcctgtat gagcaatttt atatttattt ggaatcaata
    33541 gtttcacatg aaaatcgcta gtctcactat aaaatgggtc gccaatagtt tcataactct
    33601 ttaaattcca tcccctttca tcatttacac aagctatagg aaaccaatta gtaacattta
    33661 tagtattttc tccatatcca aatcttccaa ttgaatttgg tatttttacg ttatatttta
    33721 tatctaatga cattctttca tttggtttta actctttccc taattctatt tctaatatgt
    33781 catttttgtc tcctttaatt ttatactcca ttttactatt attatttaat atattcttta
    33841 tatctatata tccttcgtta aatccattag gataagccct tgtcatttca cttttttcaa
    33901 aaggagcaaa atctttcttg gaaaaagcat tcggatatat atggaaatat attttatcta
    33961 tgtttgattt tgtattattt atgtagtcaa cattctgatt gcacattaac ctcttagtct
    34021 catcatcaaa tataacatcc atattatact gatttatttt tgaattagtt ttttctttgt
    34081 atgtttctaa actgtcatcc ttttctataa agcaacctat tattaatacc ataaatagaa
    34141 tcgctactga taatgttctt cttacttttt ggttgaattt tataaccaaa atatctcctc
    34201 cttttcaaaa tgaatacttt tagaaaatat ttacatgcta atcttgtgac cttttatttg
    34261 tttacagaca aatataatat aaaaaatgat ataatttaat ctgaggtgat aaaatgtttt
    34321 ttaaagaaag caatgaaata gatttaggtg aaatcactat tcccaatatc tttatagata
    34381 tatttatgcc aatggcggac gggttatacg taaaagttta tcttttagga tatagacaag
    34441 catgtgatat tacttctaat cctaagttcg acaataattc aatagccaaa aacctaaata
    34501 taccattgtc tgatgtgtta tctgcttgga aattctggga agaaaagaag attataaaaa
    34561 tacatgacaa tggagaatat gataatttta attattcaat agaattttta gatttaaaaa
    34621 atttctatat tgagaatata ttaagcaata attcatctat aaaatctaat acagataagg
    34681 ttgtatctac ttctgaaaat ccaagtatta gaaaaatgtt taattctata aataaaatag
    34741 ttgggcgata tctcgaccca agtgaaaaga tgagtattat ggatataatg aataaataca
    34801 atatgagccc cgatatgata ctttgcgcat atgaatacgt caaagataaa actggtacat
    34861 caaagccagt taaatacatt gaaggcatta ttagaaattg gtatgattca aatttatata
    34921 cgccaaaaga tgttgaagaa agctttttgg taagaagtga acgatatatt ttatataaaa
    34981 cgattttcaa tgaattggga ttttcaagac aaccatcaaa atcagaaaaa gaacttatgg
    35041 acacctggtt tgataaattt aatatggata tagatttgat aataaatgca tgttctaagt
    35101 ctaagaatat ttcaaaccca agtatatctt atataaatgg tataattaaa aattggaatg
    35161 aaaaaaatat aaaaaattta aatgatttaa agcaaaaaga ggaagaacgt atagttaagg
    35221 agaatattaa taagaagcag attaatacta ctcaaaacaa caatacttac aaaaaaacta
    35281 agtttcataa tttcaacgaa acattcactc agtatacctc tgatgagctc gatgagatta
    35341 ttaaaaaaag tcaaaaagaa aagtttaagt aggtgattaa atgaatgagg ataaaataag
    35401 aaaaatactt gctaaatatg ctaagagaag agatgataat gaactcttat tagaacatag
    35461 aaaaaatgag gtatataata gaatccctga gataaaatct atagatgatg aaatttctaa
    35521 aataggtctc agtttagcta agatagtact tttaaatccc aaatctaaag atgaaattgt
    35581 aaagaagact aaagagaata tagagtcttt aaaagtaaag aaagaaaaac ttttatctga
    35641 aagtaacata cctcttgatt acttggaaat aaagtttcaa tgtatttctt gtaaagataa
    35701 aggattttta cctaatggag aaaaatgttc ttgcctcaaa caagaaattg taaatgaagc
    35761 ttataaaatg tctaatttag ataggatttt aagtcaggaa aatttttcga attttaactt
    35821 gaatatattt tctcctaaga aaggctctga tggggaaata tctcctagag aaaatatgct
    35881 aaataattta agtatctgcg aaaattttgt tcatgatttt aagaaggata atagtgaaaa
    35941 tctactgttt tatggttcta ctggactagg aaagacctat atgtgcaatt gtattgcaaa
    36001 ggaattgtta gataaaggaa atgttgtaat ctatcaaact tcttttagaa ttttagatat
    36061 tcttgaagat tataaattta gaagagacac aaataaccaa ataagtgaag ataattataa
    36121 aaacttgttt gattgtgatt tattaataat agatgacctt ggaactgaac ttaataattc
    36181 ttttactagt ggggaaatct tcaatattgt aaatacaaga cttgttgctg gtaaaaaaat
    36241 cattatttca accaacttaa caccatctca aataggaaat acttacactc aaagaactct
    36301 ctctagaatc ttagataagt ttaggatttt agaatttact ggagatgatt tgagatggga
    36361 aagatttaaa taaaatagcc cttaaaaaac atttttttat ttttaaatag agaggtaaga
    36421 gcaaacttgc ttctctgttt aaaacttatg ccacataaat taaaacatat tttttatttt
    36481 tctatttaca tatctaatgt atcttaatct aacaaatcat ttacattctt agtagtctat
    36541 atttattgat actataaatt aaatttgcta tattacataa tactatgcta gaatgattct
    36601 aaattttata tttaaaacta tcacattgca agtaattcaa aattttgttg tatgtttaat
    36661 ttcattttta atacaataaa aatgaaatta aaaaaagata cttaaaagta tcctgtaaca
    36721 tagaaaatta tattaatttg aatttatgta cttt
//
LOCUS       DAEQJM010000035        35189 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.035, whole genome shotgun sequence.
ACCESSION   DAEQJM010000035 DAEQJM010000000
VERSION     DAEQJM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35189
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.035"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            365..1381
                     /gene="ccpA"
                     /locus_tag="KRQ43_002140"
     CDS             365..1381
                     /gene="ccpA"
                     /locus_tag="KRQ43_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HBH2742496.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(1504..1902)
                     /locus_tag="KRQ43_002141"
     CDS             complement(1504..1902)
                     /locus_tag="KRQ43_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742497.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGGQQKKSKGLFKKTKKSNPHE"
     gene            2114..3019
                     /locus_tag="KRQ43_002142"
     CDS             2114..3019
                     /locus_tag="KRQ43_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742498.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            3134..3314
                     /gene="ssrS"
                     /locus_tag="KRQ43_002143"
     ncRNA           3134..3314
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KRQ43_002143"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            3497..4714
                     /gene="cdeC"
                     /locus_tag="KRQ43_002144"
     CDS             3497..4714
                     /gene="cdeC"
                     /locus_tag="KRQ43_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HBH2742499.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDECNPCNPCNPCKPNPCNPCKPNPCDDKCECHDKCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSIPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(4815..6137)
                     /locus_tag="KRQ43_002145"
     CDS             complement(4815..6137)
                     /locus_tag="KRQ43_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH2742500.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(6188..6982)
                     /locus_tag="KRQ43_002146"
     CDS             complement(6188..6982)
                     /locus_tag="KRQ43_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH2742501.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQYEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            7092..8537
                     /locus_tag="KRQ43_002147"
     CDS             7092..8537
                     /locus_tag="KRQ43_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH2742502.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSSNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTNKYKLSKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISVISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            8566..8775
                     /locus_tag="KRQ43_002148"
     CDS             8566..8775
                     /locus_tag="KRQ43_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HBH2742503.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            8795..10189
                     /locus_tag="KRQ43_002149"
     CDS             8795..10189
                     /locus_tag="KRQ43_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH2742504.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTALPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGFDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            10429..11181
                     /locus_tag="KRQ43_002150"
     CDS             10429..11181
                     /locus_tag="KRQ43_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2742505.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDYLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            11207..11620
                     /locus_tag="KRQ43_002151"
     CDS             11207..11620
                     /locus_tag="KRQ43_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBH2742506.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDIECEYIILSDLYGASVCTAMLRLTNLHNVKLFSGMNLNMVLELLTR
                     FSDELTVEDIEQLVEESRRGIQSVTLQIKEEEEVF"
     gene            11624..12367
                     /locus_tag="KRQ43_002152"
     CDS             11624..12367
                     /locus_tag="KRQ43_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HBH2742507.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLELGDMAIIGSYF
                     KDNYKDFGNVSVEHVKTFMDEIKKIREEL"
     gene            12367..12837
                     /locus_tag="KRQ43_002153"
     CDS             12367..12837
                     /locus_tag="KRQ43_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742508.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDELLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            12854..13612
                     /locus_tag="KRQ43_002154"
     CDS             12854..13612
                     /locus_tag="KRQ43_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2742509.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            13596..14438
                     /locus_tag="KRQ43_002155"
     CDS             13596..14438
                     /locus_tag="KRQ43_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH2742510.1"
                     /translation="MTTSSKKLDTISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSSSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGIV"
     gene            complement(14598..15503)
                     /locus_tag="KRQ43_002156"
     CDS             complement(14598..15503)
                     /locus_tag="KRQ43_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH2742511.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKGVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            15865..16599
                     /locus_tag="KRQ43_002157"
     CDS             15865..16599
                     /locus_tag="KRQ43_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742512.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSVVIEKSDHEKSAVSLENFR
                     RIDLGEYVGVEESRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            16810..17991
                     /locus_tag="KRQ43_002158"
     CDS             16810..17991
                     /locus_tag="KRQ43_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBH2742513.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGEVFNKVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMIILNVKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGILGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGIHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVEIVI
                     R"
     gene            17996..18547
                     /gene="mobB"
                     /locus_tag="KRQ43_002159"
     CDS             17996..18547
                     /gene="mobB"
                     /locus_tag="KRQ43_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBH2742514.1"
                     /translation="MKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGYRVGVIKH
                     TCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQLYEDMDLI
                     IIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLNDYKNISKY
                     IESCIKNEILSISNVEIKNILKE"
     gene            18666..18941
                     /locus_tag="KRQ43_002160"
     CDS             18666..18941
                     /locus_tag="KRQ43_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742515.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIHAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            19197..20897
                     /locus_tag="KRQ43_002161"
     CDS             19197..20897
                     /locus_tag="KRQ43_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742516.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            21260..22447
                     /locus_tag="KRQ43_002162"
     CDS             21260..22447
                     /locus_tag="KRQ43_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742517.1"
                     /translation="MEAITAFCLVLISLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTIVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            22507..23670
                     /locus_tag="KRQ43_002163"
     CDS             22507..23670
                     /locus_tag="KRQ43_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2742518.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IEIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            23821..24624
                     /gene="zupT"
                     /locus_tag="KRQ43_002164"
     CDS             23821..24624
                     /gene="zupT"
                     /locus_tag="KRQ43_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBH2742519.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            24720..25280
                     /locus_tag="KRQ43_002165"
     CDS             24720..25280
                     /locus_tag="KRQ43_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HBH2742520.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            25531..26244
                     /gene="rgbR"
                     /locus_tag="KRQ43_002166"
     CDS             25531..26244
                     /gene="rgbR"
                     /locus_tag="KRQ43_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HBH2742521.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDDEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNAAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            26238..27617
                     /locus_tag="KRQ43_002167"
     CDS             26238..27617
                     /locus_tag="KRQ43_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH2742522.1"
                     /translation="MLNFMNELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGSYFSNINYLFYILAFIAWGGYYNYFYKMDYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLVFSFFRKS
                     IKLISQDKRNYVYLLFALLANTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEICLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITKSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     EQDTDSWGD"
     gene            27858..28547
                     /locus_tag="KRQ43_002168"
     CDS             27858..28547
                     /locus_tag="KRQ43_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742523.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMAGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITDSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEEFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            28766..31138
                     /locus_tag="KRQ43_002169"
     CDS             28766..31138
                     /locus_tag="KRQ43_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HBH2742524.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAEGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            31153..32055
                     /locus_tag="KRQ43_002170"
     CDS             31153..32055
                     /locus_tag="KRQ43_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH2742525.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRTQINNKCDLCGECIKVCLKDAICIMT
                     EKMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            32075..32626
                     /locus_tag="KRQ43_002171"
     CDS             32075..32626
                     /locus_tag="KRQ43_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2742526.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSYVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            32790..33662
                     /locus_tag="KRQ43_002172"
     CDS             32790..33662
                     /locus_tag="KRQ43_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH2742527.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            33826..34806
                     /locus_tag="KRQ43_002173"
     CDS             33826..34806
                     /locus_tag="KRQ43_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742528.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRVYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
BASE COUNT        13913 a         3633 c         6184 g        11459 t
ORIGIN      
        1 agattgctgg agagacattg acataatgtc atggatacct ttcttaatat tattgctaat
       61 aacttgttca tgtggtggat tctttgatgg tgaagtaggt tgcggctgct aatacttaaa
      121 tcattagaat aaaaaaatgc tggtatttta taccagtatt tttttatttt attttttaat
      181 atgatttaaa ttaagaatga atattattaa atttgttgaa tatagggtat aatataaaat
      241 ataatgtatt taaatgtact tgcttttatg gtaaaataaa aacttatata aatgtagtta
      301 aaataggaac cttcaaaaat ttggttcagt tttagataaa tttagtaaaa taaggaggat
      361 gaagatgaaa ggcaatataa cgataaaaga tgttgctaaa caagcaggag tgtcaatatc
      421 tactgtatct agagttataa atgattcaaa acctgtaact gatgaagtca aacaaaaagt
      481 tttagaggtt ataaaagaga ctggatatat accaaatcca cttgctagaa gcttagtaac
      541 aaagaagagt caattaatag gggtaatagt tccagaagtt tcagattctt ttgttaatga
      601 ggtgttaaat gggatagaag aagttgctaa aatgtatgac tatgatattc ttttagcgaa
      661 tacatactct gataaggaac aagaacttaa gagtataaat ctattgagag caaaacaagt
      721 ggaaggtata gttatgattt catggatagt tgaacaagaa catatcaact atatacaaaa
      781 ttgtggaata ccagcgacat atataagtaa aactgctaga aattatgata tatatacagt
      841 aagtactagc aacgaagaag ctacttttga tatgacagag catcttataa agaaaggtca
      901 tgaaaagata gcttttataa tgacgagtaa agatgatact gttttagaaa tggaaagact
      961 tgctggttat gagaaagcac tttcaaataa caatatagaa ttagacaaga gtttgattaa
     1021 gtatggtgga actgattatg agagtggata caatagtatg aaagaactat tagatgatgg
     1081 aataatacct catgcggctt ttgtaacagg tgatgaggct gccataggtg ctataaatgc
     1141 tatatgtgat gctggatata aggttccaga agacatatct gttgcaggat ttaatgatgt
     1201 taagatagct agaatgtata gacctaaact tactacagta tatcaacctc tatacgatat
     1261 gggagcagta gcaataagaa tggttataaa attaataaat aaggaattaa ttgaaaataa
     1321 gaaaatagaa ttaccttata gaattgttga tagagaaagt gttacagaaa gaaaaaaata
     1381 aaactattaa aatcaatcag gtagtgccta aggcactacc tgatttttta tgtcaataat
     1441 atcaaattta ataatagatt aactaaaaat aattatctaa ttacttaaat agtttatttt
     1501 tatctactca tgagggttag actttttagt tttcttaaat aaacctttag attttttttg
     1561 ttgaccacct ggtgtatttt ttggtgcagg tgaatttgat ttacctttag taggtttagc
     1621 cttcttagtt ttagctggtt tagtatctct ttgattttct gcatctgaga ttttttccat
     1681 tatattatct agttttttgc gttgattttc atctaaaaat gctttgaatt ttgatactac
     1741 ttcatctctt ccatctaagt tcttacctat ttttataagt tcctccataa gttcattttc
     1801 tgattttcct ttgtaactat cagccatctt ttctatttta tccttgtcaa tatttttttg
     1861 tttagccatt ttttctaatg actctgtatc taattttttc ataaaaaaac ccctttctat
     1921 aaatatatat tgaattatat tcatactatt tatatataga aataatattg aagtggtgaa
     1981 ttgtgagtga tatataatat aaataaaaat tcttatagat aatatatatg cactgagctt
     2041 taaaaatgga acattaaaat atgaaaaaca tactttaata tagggcaatt atataatata
     2101 agggggaatt gtcttgaata acttactatt tttgattgga gtgattgcat tgagtaatgg
     2161 taatatctct atatttgatg ataaaaataa atcaaaagga aataatagag ttagaaaaaa
     2221 caaaaaaaat gcaaatgata aactttcaca gtctacacat ggcaatttaa ggtttgatgc
     2281 aaatgatata aaaagaggtt taaggctcat ggatttaagt gaagaagatt tagaaatggg
     2341 aatggaaata ataacaagaa ctaaaaaata catgtcaaga gatgaaagaa aaatactaat
     2401 aaaaatagaa agtgttttag atttagttag aggaataaaa aaattaaata atatagatat
     2461 ggtagataca gaagatgaaa cggatttttt cagaaaaatg gatagtgatg ataaaaagaa
     2521 tatgatgata aaggaaatta tagatgtatt cccagaaaaa agaaaaaatt cagttgaaaa
     2581 agctatagga atgaaaaaga agatagattt atttgcagaa ttatttttac cagatgactt
     2641 tggtgaaggt ggatttagtt tgagctcttt ggcaaatata aacaatcttg gtagtatgaa
     2701 taatctcaaa ttgttaggaa gtcttttaag aggtgatgat agtaataatg atgatgaaga
     2761 caataatgat gagttaaatt atgaagacga agaattagat tgtgaagaca aagaattgga
     2821 tgatgatgag ttaacagatg aaggtgaaat ggaggataat gaagatgaat tagtagaaga
     2881 taagaacaca ggctatgaaa atatagaaaa tgatgaagat atagtatacg atgaggaact
     2941 atacaacatt aatgagcaag aatccgaata caattataat gaaaaaaata ctaaaactag
     3001 agctaagaaa aaacgataat taactaaata cataaagaaa aaaggaagaa aaagtaatga
     3061 tagaataaga ttatctcaat tactatataa aaccacttta aaaaattcaa aatttattat
     3121 ataataataa tatgaaatcc tgaaacatac gataaggctt ttttaaattc aacctacaaa
     3181 tgaaatacgg gagaccgtgt ctggtaaatt ataacatgcc tagttagttt ggacgttaaa
     3241 ggttactggc aagtcaccca cctgggagtg cctagggtgt gaatttactt agccaccggt
     3301 gtttcgggac aaaaaaagtg ctactatttc aaatagtagt acttttttta ttaatatgca
     3361 tttttctact aaatacgcct aattattgat aaattcaaaa agcaagtaac aattaagatt
     3421 ataaaagcat agtattaatt aggcttcaaa aagccaaaga cttaataaga atcgcttaca
     3481 gggagggcaa tgaaaaatgc aagattataa aaaaaataaa agaagaatga tgaatcagcc
     3541 aatgtctaca atgaatgaag aagaagtgta tacagatgaa ataaattcag aagacatgag
     3601 agggtttaaa aaatcacacc atcataatgg atgtaatact gataataagt gtgagtgcca
     3661 tgatgagtgt aatccatgta acccatgtaa tccatgtaaa cctaacccat gcaatccatg
     3721 caaacctaat ccatgtgatg acaaatgtga atgccatgac aagtgtaaat gtgattgtga
     3781 accatgtgaa atggattcag atgaatgttt tgaaaacaaa tgtggaccag aatgttgtaa
     3841 tccgatatct ccaagaaact tctctgtatc aaatgcagtg ccatttgcaa tagaggctaa
     3901 tagaatattt gatactatgc aattccaaac atttacagat gcaacaggtc caaatggaga
     3961 accattaact tttgaaacag aagtagtaga agtatttggt tcaattccaa gtgcaggtca
     4021 agcaagtgta actatagaaa aaatatgctt aagtaatgat ggaatagtta tagacacagg
     4081 aatgacaact ttagaagatt tcgatttaga cccattagga gatatagtag gaagaaactg
     4141 tgaaacaact tttgaatttg cagtttgtgg agaaagaaac gctgagtgct gtagacaagg
     4201 aaaaggcaaa tcagtagctt ataaacaaag aggattaact gtagcagttc gtaatttagt
     4261 actagagcta agaggtagat gtggatgtac agagttcgtt gcattagctt tcccagcagt
     4321 tagagcagga ggtggatgta agagaagagt tgattatgta gaatttactt ttaacacact
     4381 ttcagcacca atatgcttgc cagctgacgg aagagctgtt actttaagac aagaatatca
     4441 aactaactta actgtagatt gtataggaaa atctatatta aaattagaat gcaacgaatg
     4501 ttgtgaacct ttctatgaat taattatacc aaatgatata gatttagtac tttgcttaca
     4561 agaaacagtt agcacattaa taagtgaaca aatagtagtt ttagcatcac caaatccaat
     4621 ccaaccaaga cttgttgata ctttctctaa agtatgtgat ttttcgcaat gtggacctaa
     4681 tcatggaagt ggaaagccaa gttgccacag atagataggt aagatatata gacagtttaa
     4741 attataaata aaaatcatct aaggaaggct accaaagtgt ataatttaca ttggtagcct
     4801 tcacgttttt ataactagcg tatagatttt agtgatttaa aaagcactat agtatgtaat
     4861 agacaagtaa agattgatac tatcgtcatt gtgtatatgt atgcataaat attaagtcct
     4921 ggaattggaa gaaatacata taaagctatt agttgaatta acatgccagt aatagtattt
     4981 atacttgaag ctaattcttt tcttattgaa tgtaaaatgc cagatagagt ttgatttagg
     5041 gacataaata gtggaactaa aaacatagct tttagatatt ctcctgcaag tgtattttta
     5101 aatactaata tacataaatc ttttccaaag aaataaaaaa atattgatga tagtatgcct
     5161 acaaataaag taagaagtat ggagtatttg atttttttaa ttacactctt acgctttctt
     5221 agagccattt cctgtgaaat agttggtatt aaatttacaa taagcgctga accaacagta
     5281 aaaggtaaaa atataaaggg cattaccatc ccactgacaa taccatacat acttaaagat
     5341 tgttgataag tcattcctga taatgctaat cttgatggta tcatcataga acttatagat
     5401 tgcaaaagta tgtttgacat tctattacaa gttatgggaa tagacatttt taatgtttcc
     5461 atagaagaat tataaaaatc ttttatgctt ataatatacc tattgtcaaa tgatgaatct
     5521 cgccataagc aaataagcat aaatataata ttgctcaact caccaataga tatacctaat
     5581 agagctatat aacaattcat agatttatta tttatgtaca taacaagtaa aaaaacaaat
     5641 aatattttac caatttgttc aatgatttgt ccaatagcag ggatttttac attctttatg
     5701 ccatagtaat atcctcttag tacgtttgaa agagttatta taactatagc aggacaaaca
     5761 gctagtataa atagatttaa tttagcatct tttaaaaatt taagtgataa aaaagaacta
     5821 ttgaaagatg caactataga tataattagt gctacgaaaa atgatatata taaagttgat
     5881 ataaatagag cattagtatt gtgtctatcg tttaaagctt ttctctttgc aactagacaa
     5941 ctaagtgcag taggtatacc tgttgttgta acagctaagc aaatcatcaa aaagttaaaa
     6001 atcatatgat agatacctaa acctgtttca cctagtgctc ttgataagaa tattttatat
     6061 aaaaaaccaa atattcttac aataaaattg gatataaata aaataactgt tgatagtact
     6121 aaataaggta ctttcaaaaa aatcacctcc ttatctttta aatatattca caaggaggtg
     6181 taaaaattta taattttata aattctggtt tcaatttatt aaatttagat acatatttaa
     6241 atcccatatt ttttagtaat gaatatatgt agtcaaactc acatgcaact tgacttatat
     6301 gatgtgaatc tgaacctgtg gttatgattt cccctcccaa gtctttgtac atttgaagta
     6361 tatacttaga tggggttagg tctggaagat tatatctata acaagaggta tttatctcga
     6421 tacctttgcc atcataaata gcttgtttaa gagtttcttc aattatatca gaaaatagtc
     6481 tatcatctaa aatagtgtca taaggtgcat accttttaat caaatctaaa tgacctaaga
     6541 cagagtaatc tttataattc ttaacaatat tatataaata aagatagtaa ttttcataaa
     6601 cttcatattg agttttatct ttaaaataat taccaaggta taagtccatt gtatctatag
     6661 catggataga acatattata aagtccaatg gatattgatg tgcttccttt ttgtatgtat
     6721 ccattaattg agtttgaact ccaaattcaa ttcctttttt tattgatatt ttatctttgt
     6781 atttgctttg aagagtctct aaactcttaa aataatcttc gtagacaatt gaaaaagaat
     6841 catcagcata tacatcatag tcaacatggt ctgtgaaaca aatttcctcc aaaccgagtt
     6901 caatagattt ttttaccatt tcttccattg tagattttcc gtctgtagag aaacttgagt
     6961 gcatgtgata gtcgtaaaac ataaatattt ccccttttta taaaaatttt ggtattatat
     7021 atacatacta aataatatca aatatatata aaagcatcaa taaaatataa atacaatgag
     7081 cggtgataaa tttggaaaaa tacagaatag atttaaatga gaaaaaatca actaaatata
     7141 tacagatatt taatcatata aaagaattga taataaataa agagttagta gaacatgaaa
     7201 aattgcctcc aataagaaaa ctatcaaatt ttttacaagt aaataacact actatagtta
     7261 aggtatacga gcttttagaa aatgaaggat atgtatataa aattataggg agtggtactt
     7321 ttgtatcaag ttcaaattct tataaaagcg gtatagataa caggaaaaat aagattattg
     7381 tgcaaagaga agatttaatt cattttgaca atgggaatcc atctaatgat atgtttccta
     7441 tcgattcatt taaaaatgct gtaaatatgg cattatctaa agatggtagt tcaatatttg
     7501 aatatgatga aggtcttggc tctgaagaat taagagaaaa aatggtagag tatctaagtg
     7561 atggaaatat aaaaactact aaggaaaata ttcaaataat atcaggtgct caacaaggta
     7621 tagatatagt ttgtaaagga cttataagtt attcagatgt tgtttttatg gaagaacctt
     7681 cttacaatgg agcaattgaa gtgtttaaaa gtagaggtgc aaaaataata tctataccta
     7741 tgttagatga tggaattgat ataggtattt taaaattaaa gttggaaaaa ataaaaccaa
     7801 gacttatata cattatgcct aattttcaaa atccaactgg aatatcttac tcaacatata
     7861 aaaaaaagaa attgatagaa ttggcagaag aacatgattt ttatataata gaagatgatt
     7921 ttataagtga ttttgttttt gaatcaaagg acaatagaac aattagaagt tatgatgata
     7981 aaaatagagt agtatatata aaaagctttt caaaaatact tatgccaggt cttaggatag
     8041 gaattgtaga aatgccaaat gagttgttaa aaaaagtttt atgggctaaa tattcatcag
     8101 atatatcaac accaggttta attcaaaaat caatgtatta ctatatgaat aattttgatt
     8161 ggaagaatta tttgagtcat atagagaaga tatatactaa taagtataaa ttgtcaaaaa
     8221 acttgattaa tgacaaattg agtggtaaat taaaagttag aaaatcttgt ggaggaataa
     8281 actttttttt agaattacca agaggatata catctcaagc atttacaaat tttatgttaa
     8341 acaaaggagt gtcaatgctt ccaggaactt atttttttga caatctagtg gatgatagat
     8401 tctttaggat aaatatagct cgcccaagca tggaagaact agaaaaggga atatctgtaa
     8461 taagtgataa tatagatgag tttttttgtg aatataaaaa caagttagat ataaaaagca
     8521 ataaattatt ttattaaata aatagaggtt ttttaggagg aaaaaatgtt tgacaagaag
     8581 aaattagata ggattaatga attagcaaag aaaaataaag agggaatcct ttctgctgat
     8641 gaaatcaaag aaagagaaat tttaaggaaa gaatatttag aaaactttag agctcacttt
     8701 agatcaagac tagatagtgt caaagtagtt tcaccagaag aatatgagca atacatgaaa
     8761 aacaataaaa attagaactt agtaggagga aaatatgaac ttaaagtacg aatttaagaa
     8821 tgcttgggat tttgaaagaa aagaaaatac tattgaacaa attatgcaat attctcgcaa
     8881 ttatatggag tttttaagta agtcaaagac tgaaagactt tcagtaaaag aaattataaa
     8941 attggctaaa gaaaataact atatttcaat agatgaagct atggaaaaag gaagcataag
     9001 ttgtggtgat aagatttatg ttataaataa agagaaggca gtagcacttt ttgtaatagg
     9061 taaaaattat atagaaaaag gtatgaagat tataggaagc catatagatt caccaagatt
     9121 agatttaaaa ccaaatccac tgtatcaaga gagtaatcta ggttttttta agactcatta
     9181 ttatggtgga ataaaaaaat accagtggac agctcttcca cttgctttac atggtatagt
     9241 tatattaaat gatggaacaa aagtggacat atctattggg gaagaagata gtgacccagt
     9301 attttgtgta actgatttat tgattcattt ggctggagac caaatgcaaa agaaactatc
     9361 agaaggaatt agtggagaag ctttaaatat attaattggg aatattcctt tagaagatga
     9421 agaaaaagaa cctataacag caaatatatt aaagatttta aatgagaaat acaatatagt
     9481 tgaagaagac ttattaagtg ctgaaattga agtagttcca gctggtaagg ctagagattt
     9541 agggtttgat aggtctatgg tgttgggata tgggcatgat gatagggtat gttcatatgc
     9601 tgctgtaaaa gctatactag aaactgaaca accagaattt acttcagttg cattatgtgt
     9661 agataaagaa gaaattggtt ctaaagggaa tacaggtatg cactcaaagt tttttgaaaa
     9721 tactgtggct gaactgattg ctttagaagg agattattgt gatattaaag taagaagagc
     9781 tttagcaaat agtaaggtat tatcagctga tgtttctgct ggatatgacc caaattttgg
     9841 agaagcatat gaaaagagaa attcagcata tatgggaaat ggagtagttt taactaagta
     9901 tacaggttca agaggaaaga gtggatgtaa tgatgctaat gctgaattta tgtcagaagt
     9961 aaagagaatt tttaataaag gaaatgtagt atggcaaact gctgaacttg gaaaagtaga
    10021 ccaaggagga ggcggaacta tagcccatat attggcaaat caaggtgcag aggttataga
    10081 ctgtggtgtt ggagttttaa atatgcatgc accacatgag attgtctcta aagtagacat
    10141 atatgaaatg tataagggat ataaggcatt ttttaatata aatttataag taaaaatata
    10201 aatgtaataa gtgaataaag gctgttgtat aaacaattta atctgttgta caacagtctt
    10261 atttttatgt aaaaatagca atttgtcaca ctagagaaaa taaaagaaaa tactgtcaaa
    10321 ttaaaaatta tttaaaaaaa aattgacaac gatttcatct tgttataata tgtaataaag
    10381 aacttgttat ataatgttat aaaaatgtta catagggagg tgagcaaaat ggatgaaaag
    10441 agacaaaaaa aagaaatgga tttagaagta aattcctttg ttcctttata tcaacaacta
    10501 tatgacaaca taaaaaaaca aatagcatct ggcatatata aaccaggaga taaacttcca
    10561 tctgaaggag acttatgtaa agaatttaat ataagtcgta taactgtgag aaatgcactt
    10621 aatgaacttg taaaagaaga tatattatgt aaaaaacgtg gtaaagggac ttatgtaaca
    10681 ataccagaga gaatagaagc aacatgtgca ggaaatagtt ttactaattc ttgtcatcgt
    10741 attaatgcaa aaccaagtac caaaataatc tctgttttaa taaaaaaagc agataagcaa
    10801 gtagctgaag ctttaagtat tgaactagaa gagaaggtaa tatgtattaa aagacttaga
    10861 ttaatagatg aagtacctgt tatttttgaa gttgactatt ttagaataga ttacatgttt
    10921 ttattaaaag aagaattaga agataaatct ttaatggagg ttatatctaa taatataagc
    10981 acattaccta aacgagtaga aaatatattt gaagtaaaac attcaaacaa agaatattct
    11041 gactatctta aatgtgcaag taatatgcca ctattgaaag taagacaatc ggtgtataca
    11101 gaaaataatg atgtcttata ttacaatgag caatttataa gaagtgataa gtacaaatat
    11161 gcagtatcag cagaaatata atctatattt agtaggagga tgaagtatga aaaagataat
    11221 attagcatct catggagatt tttcaaaagg gcttttaaat gcagtaaaaa tgatagtagg
    11281 agatttagca gattgtgtta gttcgtatgg tttgtaccct ggacaaagtg cttcagattt
    11341 tgctttagaa ttagaaaaaa caatatcaga agatatagaa tgtgaatata taattttatc
    11401 tgacttatat ggagcaagtg tatgtacagc aatgttaaga ttaactaatc tacataatgt
    11461 taagttattt tctggaatga atttgaatat ggtattagaa cttcttacaa ggttttctga
    11521 tgaattaaca gttgaagata tagaacaatt agtggaagaa tctagaagag gaatacaaag
    11581 cgtgacatta caaattaaag aagaagaaga ggtattttag tttatgaaaa aaaagggaat
    11641 attatcagta tttaaaagta aaaaaccaat tatagcaatg atacacttaa aaggagatac
    11701 tccagaagat atctttgaaa gagctaaaaa agagattaca atctttgaag aaaatggtgt
    11761 agatggaata atgttagaaa attactatgg taattattat gatttagaaa gaatacttga
    11821 atatgtatca aaagctaatt tgtcaatacc atatggagta aattgtttaa atgttgatac
    11881 tatgggattt gaactggcaa caaaatataa tgctagttat atacaggttg attctgtagt
    11941 aggtcatgtt aaacctagag acgaagctac tttagaagaa ttttttaaat tacaacgttc
    12001 aaaatgccca gcgtatttaa ttggaggcgt acgttttaaa tatcagccag tattatcaga
    12061 aaatgacgtt gaagaagatt taaaaatagg aatgacaaga tgtgatgcta tagcagttac
    12121 agaaaatgct acaggtcaag aaacatcaat ggaaaaaata gaactgtttc gtaaaaattt
    12181 aggagacttt ccattggtta tagctgctgg agttacatta gaaaatgcaa aaaaacagct
    12241 tgaattagga gatatggcaa taataggaag ttactttaaa gataattaca aagattttgg
    12301 gaatgttagt gtagaacacg taaaaacatt catggatgaa atcaaaaaaa ttagggagga
    12361 attataatga ttaaattagt aagagtagac cacagactta tacatggaca agtagcattt
    12421 acatggacaa agtttttaag cacagactgt atattgatag caagtgatga attattaaaa
    12481 gatgaattaa gaatggcagg gcttaaaatg gctaaaccat ctaatgttaa gttagtaatg
    12541 aaaagcatag cagattctat aaaagcactt aactcaggtg ttactgataa atataactta
    12601 ttgatacttt gtgaatctgt agaagatgtt tatagacttg ctaaagaggt aaaagctatt
    12661 aaatctataa accttggtgg aacaaaatca gatgataatc gtgaaaatat atctaaagca
    12721 gtgcatgtat caaaagatga tataaagatg attaaagagt tagattcaga aggcgtaaat
    12781 gtatttgtac aattagttcc tgatgatgat gctacaaatg taatgaaatt aatataattt
    12841 tagggggatg aaaatggaat ttacacaagt tattttgata actctaattg cattctttgc
    12901 atatatgcat agttttgtag gttctacaat gcataataga cctatagttg ttgcaccact
    12961 tgttggttta gcactaggta atcttcatac aggtatagta ataggttcaa cattagaatt
    13021 agtatttatg ggtgcatttc ctgttggggc aagtaatcct cctgattttg tgtctggttc
    13081 tattattgcc acagcgtttg taatattaac gggtcaagat gtatcagcag cagttgtact
    13141 tgcagttcct atagcaactc tagtattgct tatagataac ttcttaatga cagtagtact
    13201 tacatgggga gctcatattg ctgaccgtta tgcagaagag gggaatattg aaggcgtaga
    13261 acgtgtgcaa ttattatttg gtataggaaa taaattaata ttagcaataa tagtaggtat
    13321 aggattttca ttaggtgttc cagtaataga aaaaatactt tcatttatac catcatatgt
    13381 aactcatgga atggatgttg cagcaggcgt gattccagca ataggttttg ccatgttagc
    13441 taggatgatg cttaataaga aaacagtagc atttttatta ttaggattta tattggttgc
    13501 ttacctaaac ataacagtaa caggagttgc attgtttgga ttagcaatag ctttaatata
    13561 tgttaacttt gtaggagaga aggaggtaat agtagatgac aacgagttct aagaagttag
    13621 atacaatttc acccgatagt aaaataacga ggaaagactt ttggaaatgc tttagaaggt
    13681 cattgacatt agattcatct tggaactacg aacgtatgca aaatatagca tatgcataca
    13741 tgatggcacc aataatccgt agattgtata aagatgataa ggaaaagaaa tctaaggctt
    13801 taaaaagaca tttagaattt atgtcagtta ctcctcatat aagtactctt ttggtaggta
    13861 tatctggagc tatggaagaa gaaaatgcaa agaataaaga atttgatgct aatagtataa
    13921 atgctgttaa atcaagttta atgggtccag tttctgggat aggagattca tttttctggg
    13981 gaacattaaa gcttatagca gctggagttg gtatagcttt agcttctcag ggtaacataa
    14041 tgggaccgat tttattcctt ttaataataa atgttcctca ttttattata cgctatatat
    14101 gtctagataa aggatttaag tatggaactc aattctttaa agatgtgagt agttcaagta
    14161 tagtttcaaa agttatggaa gcagcttcaa tgttagggct tatggtaatt ggaggtatga
    14221 ctgcatctaa tgtaatgtta aaacttagtg ttaatgtagg tagtggagaa tgggcagagc
    14281 ctattcaaac ttacttagac caaataatgc catgtatgct tccagctatg atattcggta
    14341 ttatgtattg gttattagga aaaaaggtaa agacaactac gatattaatt tcagttatga
    14401 ttatttgtat agtattagct gctattggaa tagtataaat aaaaaaatcc caagttcatt
    14461 tgaacgaggg attttttgac taaattaaat aaaaaagaaa gatggttcat aataatttat
    14521 aagcatttat gtgatagtta taattagctt attaattagt tataaaccca aaattaagca
    14581 ctactttatt aaagttatta tattataatt tcgaaatact cacataatct gtttagaaat
    14641 ttatcttcta atggggaaaa agttttcttt ttagagtaaa taaagaaaaa ttttctagta
    14701 aaatcaacac cctttatttt ataacatttt attttacctg cattgagata atcaatagct
    14761 gaaatgtacg atataaagga gactccaaga cctaatctaa ccatttcctt aatagcctca
    14821 tttgattcta catgagctat tacatttaat ttacttactg gaaagttatt tttactaagt
    14881 gtgtttagta ttaagtttct tgtacctgac ccttcttttc tcataataaa atttagataa
    14941 gccaattctc ctatatcgat acaattattt ttattatcaa ttttaaaatc tgaaggagtg
    15001 ataagaacaa gttcatcatc taataagtct aggtactcta tttgaggatt attgatttta
    15061 gaaccaacta atccaaagct tattcgttca tttaaaattt ctgatatagc atattgagaa
    15121 tcataatggc ttatggaaaa ttttacatct ggataactca tagaaaaact cttcataaaa
    15181 tcaggtaaaa tataagtttc aggtatggaa ctacatgcta tatctataat accttctatt
    15241 tttcctgaat attcttttat atcataaatt gcacgtttgc aattattcaa tatatatata
    15301 gcatgttcat aaagaatttc accagatttt gtgagtgtaa taactttgtt gcttctattt
    15361 ataagaacag tttccaactc tctctctaaa ttctgtatgt gtgcacttac agtaggttga
    15421 gttaaaaaaa gttctcttgc ggcctttgaa aaactctgat gttttgcaac agcaacaaat
    15481 acttcaagtt gtttaaaatc cattatttaa tcctccttaa attatctaaa actattataa
    15541 catatttgat aaattaatag tcaaaggtga tttttaaaat agaaaacctt taaatattca
    15601 tggagttttt gattgtttag gaataatttg gtataatatt gtaaggtact tacaataaaa
    15661 atatcgtaaa ttgaattttc aaaattcaac tttaaagtgt tttttattac agaaaaatta
    15721 caattagctt cttaatctta ttaaattcaa ataaatatta tataattatt ttataatata
    15781 ataaatataa ttattgaaaa aagagataac tgtaaattga gatatagata aatactataa
    15841 aatttaagaa aggaggattg atttatgaag ttaaaaaggt cattagtttg tgtaactatt
    15901 ttaggtatta tacttgttgg atgtcataaa gaaaatacta aagagaaaaa tcaagtagca
    15961 agtaaagcaa cacagcaaaa aactatgaca aaagttcaaa atgatgttaa tgaaattatg
    16021 aataaagatt ataagtacat tataaagaat atgggtatac cttataatac attttattat
    16081 ataaaaccta aagttttaaa agaatcgaat acaatgcaag atataaatac atcaagttat
    16141 atgacattag tttatccaaa atatactgga aatgatgaac tagatggaag tgctttatat
    16201 gttgatatta acgaaaataa agttgtcaat gttgaaacca attctttctc atcacaaggt
    16261 atatcagtca ttgatgctga atctagtgtt gtgattgaaa aaagtgacca tgaaaaatcg
    16321 gctgtatcac tagaaaattt tagacgtatt gacctgggag agtatgttgg tgttgaagag
    16381 tctagaataa atgaaattgt aggagatgcg aattatgatt taacagcata taatcatgaa
    16441 ggtagtaaag tagttaagag ttatagattg aaagaagata acaaaatatt aaaaaaagag
    16501 gtacttacaa taagtattgt ggataacaaa ataaaatcta taaaaactat tgaaagtgat
    16561 aaaattgtaa aaataataaa aggaacttta ttagaataaa atattctaaa gcatatgatg
    16621 ctgtttcaag atagaaggaa atttctagct gggaacagtt tttttattag atttataaaa
    16681 tttgaactgc acttatagat aactattagt tataattaaa tataagataa aagtatttcc
    16741 aacttttata atctataata tattacatag aaatatctta aataaaaaat atattgggga
    16801 gtatttaaaa tgatagaatt agaagatgcc ataaaaatta ttgaaaaaaa tgttttacca
    16861 ataaacaggg tcaagatagt aaatcttata gatgcagtaa ataaagtagt tgcagaagat
    16921 atatattcaa caattgatag tcctccattt gataggtcac cctatgatgg ttatgcatat
    16981 aatgcaaatt ctgaaaatag aaatttaaag gttataggga ctttgtatgc aggagaagta
    17041 tttaataagg tattaaataa aaatgaagca gtgaagataa tgactggtgg aaagatacca
    17101 cagggtgcaa actgtgtaat aaaaaaagaa gatgtaacgg ttataggtga tatgataatt
    17161 ttaaatgtaa aattaaagga atacgataat tacatattta agggtgagga tataaaaaag
    17221 gggcaattga ttattaataa aaatcagaat ataggatatg atggtattgg agtattagca
    17281 agtcttggaa tatccaaagt aactgtttat gatgatttaa aagttggaat tttgaataca
    17341 ggtacagaac tacaagatat aaatgagact ttagagaatg gtaaaatata cgatagtaat
    17401 agatatacct tatattcaag attattaaaa cttggaatac aggcagatac aatatgcaat
    17461 tgttctgatg atatattgga gttagaaaaa aaggtaaaga atatgttaca gagtgtagat
    17521 tttttaatta caacaggtgg tgtttctgtt ggagataaag atttaattcc agatgtattc
    17581 aaaaaaatag gggcaacaga attattttgg aagataaaca ttaaacctgg tggagcttgt
    17641 tatgtaggta tattgggaga aaagctatta tttggtcttt ctggtaatcc acatgcagca
    17701 atagtggtat ttgataatgt gatagttcct gttattgagt atttaacata taagaaggga
    17761 atacatcata taaaagctat atttaaagga gaatttaata aactttcaaa taaagataga
    17821 tttgtaagtg gaaaactata tacaagtgaa ggtaaattgt atgtagagct aaatgataag
    17881 aaagatgcaa aagctagatt atctgcaact ctaagaagta attgtatgat taagattaaa
    17941 aagaatgaga caataaaaga aaatcaatta gtggagattg ttattagata gttttatgaa
    18001 aggacacaat tttatgtata atatattgtc agttgtctca tattcaggag taggtaaaac
    18061 tacgttgatt gaaggcataa taaaagaatt aaataaaaaa gggtatcgtg ttggagttat
    18121 taaacatacc tgccatgatt ttgatatgga tgaggaagga aaagatactt ataaacatag
    18181 aaaatctggg gcgagaaaag tctgtataat atcagataaa cgagtagcat atattgaaga
    18241 actaaaagag aagaatccat tatataaaat gattcaatta tatgaagata tggacttgat
    18301 tatcatagaa ggatataaaa attatagatt taaaagattg gaagtaacta gaaaaggtaa
    18361 gtatgaggat attttatcta ataagtctga tttgataggt attgtcagtg atatagaata
    18421 taaattgaat attgaacagt ttaatttaaa tgattataaa aatatatcaa agtacataga
    18481 gtcttgtata aaaaatgaaa ttttaagtat aagcaatgtt gaaataaaaa acatattaaa
    18541 agaataattt taagatgttc ttcttatata aaatgatata attatttata taaataaaga
    18601 tataagaaat ttatcaattt tattttgagt tataaaatat taaagaaatt gtaggaggac
    18661 aatatatgaa aaaaatatta gtagcatgtg gagcaggaat cgcaacatca acaatagttt
    18721 gtgacagagt agaaagattg gttaaagaaa ataatataca cgcagaagtt gagcaatgta
    18781 aaattgctga atgttcaaca aaacaagaag gtgctgattt aatcgtatct actactatac
    18841 taccaacaac ttatgatata cctacaataa aggcaacagg atatataaca ggtataaata
    18901 caacagcatt agataaaaag atattaaatg cattgaagta gttttgtgtt tataaaaaaa
    18961 atttagtatt aaatatagag ttgtatcttt ataaaatttt aaatatagag atatagctct
    19021 ttttatgctg tttcaagtat acaactatat gatataaatc ttcaatttta tgaaaaagat
    19081 tgttattact ttgtaagttt ataaaagatt taaagttatt gttatgttat actaatttat
    19141 gggtattttt tagaagtact atatagaagt actaataaag gagggattta atacttatga
    19201 taaaacaatt tgtcaaatat tataagccat ataagaaaat ttttacacta gaccttatag
    19261 cagcttttct attttcctta tgtgatttag tttatcctat gataactaga aatataatgg
    19321 atgacgttgt tccaaataaa aacttaagaa tgttagtagt ttttgcagta gcacttatac
    19381 ttatatttat agcaaaagca gggcttaact attttatgca gtattgggga catgttattg
    19441 gtgtagatat gcaagctgat atgagaaatg aggtatttac acacttacaa agacttccaa
    19501 atacgtattt tgataataac aaatctggag taactatgtc tagaatagta aatgatttaa
    19561 tggatataac agaacttgca catcatggtc ctgaagattt attcatttct atagtaatgt
    19621 tggttggttc attctttata cttatagata taaatattcc tcttacgctt ataatatttg
    19681 ctatattacc gtttataatt tggtttgcaa tagctaaaaa agataagatg aatattgctt
    19741 ttatgaagag tagagttact ataggtgatg taaatgctac tttagaaaat agtatagcag
    19801 gtatgaaagt aactaagtct ttttgtactg agaaagaaga gttaaataag tttgtaagaa
    19861 gcaataaatt atttagaaga gcaagacaag attcttataa ggtaatggca gaatattact
    19921 ctggtatgaa tttatacatg gatatcttag agtgggtagt tgtaatagct ggtggttatt
    19981 ttacttatat aggaaaaatt actttgggtg attttgctgc ttatatacta tatgtaaaaa
    20041 tgtttataca acctatgaaa aaattaataa attttacaga gcaatatcaa aatggtatga
    20101 caggttttaa aagattcata gagataatgg aacaagacca tcaaaaagaa gctaaaaatc
    20161 ctattgaact tgaaaatgta aaaggtgaca ttgagataga aaatatatct ttcacatatg
    20221 aagataagac tcaagttttg gataatttaa gtttatctat aaaagctggt aagactatag
    20281 cattagttgg accttctgga ggaggaaaga ctacattatg taatctattg ccaagatttt
    20341 atgaatttga taagggtgat ataaaaattg atggaaagag tataaaagat gttagtttaa
    20401 aatcattgag aaaaaatata ggtatagttc aacaagatgt atttttattt acaggaacta
    20461 taagagataa tattctttgt gggaacccta atgctacaga tgaagaaatg atagctgctg
    20521 ctaaaaaagc tagaatacat gactttgtag agactttgcc agatggatat gatacttata
    20581 taggagaaag aggcgtaaaa ttatcaggtg ggcaaaaaca aagaatttca atttcaagaa
    20641 tctttttaaa gaatcctcca ataataatat tggatgaggc tacatctgct ttagacaatg
    20701 taacagaaag agaaattcaa gagtctttag aggaattaag taaagataga acaaatttag
    20761 ttgttgcaca tagattgact actataaaaa atgctgatga aatcatagta ttgacggata
    20821 aaggaattga agaaagaggt actcatgaag agttagtaaa caaaaatgga gtatatagta
    20881 ggttacacaa taactagtat acaaatttta caccatagct aacatacgca ttaaacttac
    20941 aaacatagga tatattaaga ttcataaaga caattcattt tatatttatg agatgtttta
    21001 tgaataaaat gtatcctatg ttttattttt tgcaaattac atttaattct ctttgtaaga
    21061 atagagttaa atagccaatg gtcaggataa cgtttttaca aaaagaataa tttagaaaac
    21121 taactttaat ttatggaatt tatcgaattt tatgaaaaaa atcgaatttt gacttgaaat
    21181 gtttttcaaa agtagtaaaa taatggataa ctatacatac attttataaa aatacattta
    21241 ttatgagggg ggattttgta tggaggcaat aacagctttt tgtctagttt taatatcact
    21301 gacgatagga gatatagttt cagcaaaaac taaagctttt gttccgtcgg tttttgtatc
    21361 agcaattata tttatagtag gattctggac ttttttccca gaaaatattg tggacttagc
    21421 cgctttagga acaccattag ctcaattagg tatgcttttg ttaataactc atatgggaac
    21481 tatgatgagt attaaggaat tagcaggtca atggaaaaca atagtaatag ccttggcagg
    21541 aatagtagga atatgtgtag gtgctttggc attagggaca atagtatttg gatgggatac
    21601 agcagtaata gctacacctc ctcttactgg agggctagtt gcatctataa tgatggcaga
    21661 tgctgctaca gcaaaaggtc ttgcaagttt atcagtactt gcaattttga tgtatgttgc
    21721 acaaggattt gcgggttatc ctattacagc attaatgctt aaaaaagaag gaaaaagact
    21781 tttatcagac tttagaagtg gaaaagtaac tgtaaataca gatgaagaaa aagttaagga
    21841 tttacctgaa caaaaaagca gatttaagat aattccagac ttaccagaaa aatatgatac
    21901 gacatatatg ataatactta gattaggatt tgtagcatgg ttagcagtac aatttacaaa
    21961 tcttacaaat gaagttgtat caagatatgt tatatgttta atatttggtg taatagcatc
    22021 agaacttgga atagttgata gaaaaccact taataaatct ggttcatttg gatggttaat
    22081 gacatcattg atggctttta tatttgcagg attagcaaaa gctacaccag caatgcttgt
    22141 tgaaatggca gttcctcttg taggaatcat aatatttggt gtaataggta tgggaatatt
    22201 ctctattata gtaggtaagc ttttaggtga aagtaaagaa atggcttttt cagtttcgct
    22261 tacatcactt tatggttttc caccaaacta tatattaact gaagaggcag taaaggcttt
    22321 ggctgaaaca ccagaagaaa aagaattttt aatggataag atgcttccaa agatgcttgt
    22381 tggaggattt actacagtta caatagcttc tgtagtaata gcaggtatct ttgtaaatct
    22441 aatatagtat ttaagtgata aaaagtattt taaataagaa gaatgtgtac tacttggagg
    22501 tatggaatgg atattaaaga aataacaaag agttataaag actatgtaat taagcttaga
    22561 agggaatttc atgaaaatcc tgagaaaagt atggaagaag ttagaacatc aaagagagtt
    22621 aaagaagaac ttgataaaat agagatacca tatgtatcag ctggaggtac aggtgtaatt
    22681 gcaactataa aaggagctaa tccaggaaag actgtagcac ttaggggtga tatggatgct
    22741 ctacaagttg ttgaatgcac tgatgtagaa tacaaatcta aaaatgaagg acttatgcat
    22801 gcttgtggtc atgatggtca cacatcaatg cttctagggg cagcaaaagt gttaaatgat
    22861 attaaggata gtatcaatgg aactgtaaaa ttattttttc agccaggaga agaagttggt
    22921 aaaggtgcaa gagctatgat tcaagatggt gctatggaag gtgtagatag tgtgtttgga
    22981 atacatcttt ggactgatgt agaatctggg actatatcgg tagaagaagg accaagaatg
    23041 gcttctgccg atttctttaa aattactgta aaaggtagag gtggtcatgg ttcacttcct
    23101 catcaaggtg ttgatgcagt gcttgcaagt tcagcaatag ttatgaatct acaatctatg
    23161 gttagtagag aagtaagtcc tctggaacca ttagttgtga gtgttggagt tttaaattct
    23221 ggaactagat ttaacgtaat tgcgagtgaa gctgtcttag aaggtacaat aaggctattt
    23281 aatccagagc ttagaaagca aattcctgga attttagaac gtatagcaaa atctacagca
    23341 gaagcatata gagcagatgc tgaattagag tatgggtact taacaccagc agttataaat
    23401 gacaaagaat gttcaaagat agctacagat gcagcaatta agctatttgg agaagactgt
    23461 ataacactat ttgaaaaagt aacaggagca gaagatttag ctgagtttat gaatatagca
    23521 cctggtgcac tagcatttgt aggagctaga aatgagtcaa aaggtgcttg ctatcctcat
    23581 catcatggat gctttaatat agacgaagat gctctagaaa ttggaactgc tttatatgtg
    23641 caatatgcag tggatttctt aaataaataa ttttaatata ctataaagaa aaagcagaga
    23701 ctaagtttat atctctgctt ttttattgtg tatatttttt ataaatattg actatataaa
    23761 atatatatga tagcataaag aaaatgataa tcaatatcaa ttaaaaagaa ggtgatttat
    23821 ttgaataatg taatatttgc atttttgata acattattgg ctggtttatc tactggtata
    23881 ggaagttgta tagcattttt tgctaaaaaa acaaatacta agtttctttc tataagctta
    23941 ggattttctg ctggtgttat gatttatgtt tctatgatag aaatttttcc taaagcacaa
    24001 gatgctttga caaaatctat gggagagaaa ttaggaagtt ggtcaactgt aatagctttt
    24061 tttataggta tggctatcat tgctgttatt gataagttaa ttccacaaga agaaaatcca
    24121 catgaaataa agaaaatgga gaatatagaa gaaaagaata tcaaaaaaaa taagtctctt
    24181 ttgagaacag gtatatttac agcaatggct atagcaattc acaattttcc tgaaggatta
    24241 gctacattta tatcagctct tgatgatgtt acaatagcta tcccgatagc aattgcaatt
    24301 gcaatacaca atataccaga aggtatatct gtatctgtac cagtttatta tgccacagga
    24361 gataaaaaga aagcttttta ttattccttt ttatctggta tgtctgagcc tttaggagcg
    24421 attattggat atgtacttct tagaaatttt ttaaatgata taactcttgg aattgtattt
    24481 gcaattgtag gaggaattat ggtattcata tcactagatg aattattgcc atcagctaga
    24541 gagtacgggg aacatcattt atctatttat ggattgattg caggaatggg tgttatggct
    24601 attagtttat tactatttaa atagcttttt aaatatatga ttgtaaccta aaattagtat
    24661 caaaatgata taattattta aatagatttt taagctattt aaaaatatca ttttggagaa
    24721 tgagtgctat ggaaaagaaa ataaaattca aatttgactg gtatagttca cctgataaga
    24781 tagagaaatg gttagaagat attgaagcta aaggatataa tttatataag ataaataaat
    24841 ttggaggaat attttatttt cataagggaa gtccaagaaa aataaaatac actgttgatt
    24901 actactatga tgtagagaat aattattttg atgaacataa atcaaatggc tggaatcttg
    24961 tatttaggag tattggtagt tttatgggta catctgcatg gtatatatgg tcgaaagaat
    25021 acaaagacat acctcctaaa ttatatagtg attctgataa aaaaaacaaa gtaaagtcaa
    25081 ttttatttat gaatatgttt atattcttta tgttagtagt aatatttata tatttattga
    25141 atattgaaat aagaaattta tatagtggtt atggagcatc tgtaactgct attgtactac
    25201 agattatatt gttgatttta tatgcagtac aattatatag gagattaatg tattatttaa
    25261 ggcttaaaaa gtttaaataa ataaaagaag gtgtcctaaa attatttttt taatatttta
    25321 agacatcttc ttttgttagt aaagtactgt ttttaattat agtaatttct gtctttaaat
    25381 tgaaatatca aataatagtt gtattggatt gagtattgat aaaaataatt taaaaatgtt
    25441 atcctaaagt atcagatata caaaattatc tttaaatata ttataaatat tttaattgta
    25501 ttaactagaa attatgtaag gaggcatttt atgattaaga tagcagtttg tgaagatgaa
    25561 aaagaaacac aacttttaat agaagattac cttgagaata tattaaaaga tataagtata
    25621 gaatatgaga tacaaaagta tatatctgga gaagagttac tggaaagtaa tttaaaagat
    25681 atagatatat tacttcttga tataaaaatg gaaaaattaa atggaatgga tactgcaaga
    25741 aagattagag aagtagacga tgaaatggaa ataatatttg taacttcatt aatagattat
    25801 gtgcaagaag gttatgaggt aagagcttat aggtatttac taaagccaat agagttggaa
    25861 gaactaaaaa aacatgtgct aacttgtatc aaagatattg aaataaataa ggaaagtcat
    25921 attacaataa aaaataagtc taatacatat aagatttatt taaatgaaat aaaatatata
    25981 gaagttcaaa aaaaagatat gctaatacac acaataaaca agaattttga tataaaatat
    26041 agtttaggta aaatagaaaa agaattaaat ccatataaat ttataagatg ccataaaagt
    26101 tttatagtaa atttaagata tgttgaaaat ataaagccta atgctgcaat actggaaagt
    26161 ggagaagagg tacctattag tagatataga tataaagaag ttaaggagaa atttttaaaa
    26221 tttcttggtg atacaatatg ctaaatttta tgaatgagct attagtagtt ttatctatat
    26281 ttatacagtt ttctataatg aacggaattt taatttataa aaaggatagt aaaaaaaatg
    26341 aaaaaatagt attctatatt gtcttgtttc ttatttatat tataattcag ataagtagat
    26401 tatttaatgg aggaagttac tttagtaata taaactattt attttatata ttagcattta
    26461 ttgcttgggg aggatactat aattattttt ataagatgga ttatattaag tattccattt
    26521 tcttttatct atttagtgta tattataaat gtttggatgc tgttatatat agaatactat
    26581 tttttgcaat tacaggtaat gttatttcat ctaaagaatc cttattagta cctcacttag
    26641 aatctataaa aattcagata tatagtaatt taataattat tcttatatat cttgtattta
    26701 gcttttttag gaagtctata aaattaatta gccaagataa gagaaattat gtatatttat
    26761 tatttgcctt attagctaat acaatgaata tgcttgtaaa ttatgtatta aaaaaattag
    26821 aacggtttgg gtcattacat tcagaaggat actattttga taattttgtt aatccaaagt
    26881 tggtaggagc tagtagtata tttcttatat tattgtttaa agaaataata aaagagaata
    26941 gattaaaatc tcaagctgaa ttaataaaaa ataagttaga tatgcaatat gcgcattatt
    27001 taagtattca agaatctcat atgcgagtta agaaactata tcacgatata aataaccaca
    27061 tttattgtat agacaacctt agaaacaata gcaaagaaat taatgaatat gttaacaatt
    27121 taaaagatga aataaaaaca tttaaatata tctataatac aggaaatatg atattagaca
    27181 ttataatcaa cgaaaagagt gaaatatgtt taaaaaaagg aattaaattt acttgctcta
    27241 taaatttttc aaaagtaaat tttgtaaaac ctatagatgt gtcaagcata ttttctaata
    27301 ttttggataa tgcaatagaa gcatgtgata aaatagtgga tgaaaatatt aataaatata
    27361 ttagaattaa aggaactata acaaagtcat tttttgtact taaatgtgaa aatagtaaac
    27421 taaatcagct tacttttaat aaaaatatat tgttaacaaa caaaatggat aagttcgtac
    27481 atggaatagg tattcagagt attaaatctt ctttacaaaa atataatgga gaattattat
    27541 ttgaaaatag tatcgataaa tttatactaa atatatatat accattggag caagatactg
    27601 acagttgggg cgattaagtt accagttggg acatatgtat tgatacaaaa aaataaggat
    27661 gttatctttt aataacaaaa gataacatcc ttatttctgt attaaggagc ttataatttt
    27721 actaatagta agttataaga attggatagg aaggtgatat gtattgaata ataaatcttt
    27781 aatataaaga aaatataaat atattctaat gcaatgaata atactttaga gcggttagtg
    27841 tgatgggagg attgtgtatg aaagtaaaaa ggaatataaa tagagtggca ataattgtgg
    27901 ctttaaatct tagcttagca ttgatggcag gatgtatgtc tcctgtatct gataagaact
    27961 taagtagctc agaacaaatt agtaaagatt cattgaaaga acaagttgaa gataaaaaag
    28021 atgaatctat cgagctattt aataattact cacaaaagat taatgatgcg aaaggtagag
    28081 aagaagtaaa aaaagattta tctcaaagat tttcgaaagc tataatagac agtggttata
    28141 gtattactga ctcaaaatca gatggtagct ttgtagtatc tataaatggt gctgaaaaac
    28201 cacctgaaaa aaatattcga agtttattct attctatgtc tgaagacgat aaagaaggaa
    28261 aagtaacaat agatattctc tgtgctaaag agtatccaga agatgataag ttatctgaga
    28321 gtgataaata tattaaattt atatacaatt tatttaaatc attgactaat acgaacttaa
    28381 ctgagaaaga aattttttct atggttgaag aagaatttaa taagggagta ggtgttgtgg
    28441 agcttcctta tatgaaggat atacatgttg aagttaacaa agttaaacaa tcaactaagg
    28501 ttttaaaact aagtctagta tacaaatttg atatttcaaa tcattagtat attagaaata
    28561 actataacaa tatagaaaat atatcataga aaattttttt agattttata aatttaacaa
    28621 aaaaagtatt aatatatagg tgttcaaggt agatgaaaaa aaaagttatt ttgcttccat
    28681 tttatgctaa aggacagtat aatataatta aagtatgtta taacatacaa aaatgtagta
    28741 tatattatcc aaagggggat tttaaatgag tcaaactaat agaatagaag catttagaca
    28801 agaatatatt aattctaaac ctatgatatg ttgtgaaagg gctagaattt ttacagaatc
    28861 acataaaaaa actgagggag aagctatctg tataagaaga gctaaagctt ttttggagac
    28921 atgtaaagaa cttcctataa aaatctttga aaatgaatta atagtaggta cagcaggaaa
    28981 atttagaaga acagggatat tgacaccaga gttttcttgg caatgggtag acaaagaaat
    29041 ggatactttt gataaaagaa ctcaagaccc atatgtaata tcaaaagaac aaatagaatt
    29101 tataagaaaa gaaatatttc catattggaa gggaaaatct ttggaagaag ttttcttagc
    29161 aagaatccca gaagatacag ctaagatatt agtagataca ggaataatag ataatgattc
    29221 taagtggaga caggcagttg gtgaagtaac accagattat caagatatat tgtttgtaaa
    29281 aggatataaa gggattaagg aagatgcaga taaaaaaatt aaagaattag atatatcagt
    29341 ttcagaaaat attgaaaaga tagattttta caaatctgtt tctatagttg cagagggtat
    29401 tatgacattg gcacaaagat attcaaatct tgcaaaagag atgagtaagc aagaaacaga
    29461 tgaaaagaga aagttagaac ttataaaaat ttcagagata tgtatgaatg taccagcaaa
    29521 ccctccaact aatttttatg aagcaataca atttgtatgg tttgttcaat taggtggtat
    29581 tctatcagaa aatccattgg cattaaattt aggtagattt gaccaatata tgtatccata
    29641 ttatgaaaat gatgctagag aaggtaaaat aactgaatca gaagctcaag aattgataga
    29701 agcactttgg attaagttat cagaatgggt atggactata tcagcaaata cagcaaatta
    29761 ctttgcagga tataatcaat tccaaaatct tactgttggt ggtaaaaaga gaaatggtac
    29821 tgatggaacg aatgatatct catatatgtg tttaaaggct acagaaagtg taaaaactca
    29881 ccagccagga ttaagtgtta gagtgagtca aggagcacca gataatttcg taatggcagt
    29941 tgctaaattg gtaaaacaag gaactggttt ccctgctata cacagcgata gtgcaggggc
    30001 acaaatgtta ttacaagatg gatatgatgc agaagatgct agagattgga gtaactgtgg
    30061 ttgtgtagtt cctcatttta gaaaaacagg acagtggact tcagccgtaa atatcaattt
    30121 tgcagcagct ttagaatatg ctatgaatga aggtaagagt agattaactg gagaaaaaat
    30181 ggggttagat acaaaaaata tcacagaatt tacttctttt gaagaactta aggatgagtt
    30241 tttaaagcaa ttagcatatc ttgtaaaaag ttctgttata ggaactactg ttgctcaaca
    30301 aattcataaa gaaatggtac caagaccatt tttatctact tgtgtagatg gatgtttgga
    30361 taagggagtt gatttaagta aaggaggagc aaaatataat ataggtcctg tattaactgg
    30421 tatagggtta ggtgtagttt caaattcatt ggcagctata aaaaaattag tatttgagga
    30481 taaggtgact acgctagaag aattaacaaa agcactaaat aatgattggg aaggttatga
    30541 agaattaaga aaacttgcgt tggatgttcc taagtatgga aatgataatg attatgtaga
    30601 ttcattagca attgaagttt ctgattttta ttatactgaa actagaaaat acaaggatat
    30661 ttttggctct aaatttaata gtgcatttat gggtatatca aactatgtac caactggaaa
    30721 aatcgtaggt gcaactcctt gtggaagaaa agcgacaaaa cctttgacag agggagtttc
    30781 tccgtttgtt ggtactgata caacaagtcc actagcagcc atgaaatctg catcaaaaat
    30841 aaatcatgat gttcatactg gtggaacact tctaaattta agactgaatc aagatttggt
    30901 ggaaactgaa agaggactta gaaatctaac atctatgatt aaatcatatt ttgctttagg
    30961 aggattccat gtacaattta atacgatatc aaatgatact ctattaaaag ctcaagaaaa
    31021 tccagaagaa tataaagatt tattagtgag agttgctgga tatagtactc aatttgttaa
    31081 tttatcaaga gaaatgcaag atgctataat agctagaaat tcacatagca atttttaatt
    31141 atgaggtaga ttatgagtaa aaaaggtaga gttgtaaaag tacaacattt ttcagtaaat
    31201 gatggagatg gaataaggac tactatattt ttagaaggat gtaaattaaa atgtaagtgg
    31261 tgttctaatc cagattcctg gagtaacata gtaaaattag gtgttatgaa agataaatgt
    31321 gtatcctgta atagatgtat agatgtttgt cctcaaaata taagttcact atttgataga
    31381 acgcaaataa ataataaatg tgatttatgt ggagagtgta tcaaggtatg tcttaaagat
    31441 gccatttgta taatgaccga aaaaatgagt gttgaagaaa tagtagagga agttgaaaag
    31501 gattttatat ttttctttga atctaatgga gggataactt tttctggagg tgaacctaca
    31561 cttcagattg attttttaag agaattagtt gatatttttt atgataaagg cataaatatt
    31621 gcaattgaaa cttgtggata ttttgattgg aataaggtaa atgatgtatt tgagaaaata
    31681 gaccacatat ttgtagatat aaaatctatg gatgataata ttcataaaga atatacagga
    31741 gtaagtaata aaattatatt agataatata tgtaggcttt caaagttgaa taaatctatg
    31801 gttataagag tgccaattat ttatggagta aatgatagtg aagaaaatat aagaaatact
    31861 gcattatttg tcaaacaaaa tgttccagga ggcaagatgg agttacttcc atatcataaa
    31921 tttggaatcg ataaatataa ggcattaggg cttgaagatt atatatatga atttgatgaa
    31981 atttgtaaca atcatatgtt aaaattaaaa gagatagtag aacttacagg agtaaaaatc
    32041 atagaataca aatagctatc aggaggattt taacatggat aataaatttc ctaatgtggg
    32101 agaaaattta aggttattga gacaagaaat gggcataagt ttagacaaag cttcaaagat
    32161 gacaggtgtc agtaaagcaa tgcttggaca gattgagaga ggtgaatcaa gtccgacagt
    32221 atctacttta tggaaaattt catctggatt taaaataaat tttactacac tattaaatga
    32281 aaatacaaat acctatgagg ttataaagaa agaagaagta gagcctattg ttgagcaaaa
    32341 agggaacatg aagttatatc caatataccc ttttagccct caaagaaggt ttgaactttt
    32401 tataattgag cttgaggaaa actgtactca tgtttcatct acacatagtt atgttttaga
    32461 agagtatgta ctcgtaatag aaggtaaact tgaccttaat gtggatggga aaacttatat
    32521 tttagagtct ggacattcta ttaggtttga tggaacttta gagcatatat ataaaaattt
    32581 aaataaagga aaaactatat ttcacaatat agaggtttat agataatttt atagttatcc
    32641 ttttctaaaa taaatgaaaa ttttagaaaa ggataactta tttttataat gtcgaaaaga
    32701 tttatatgta tgtgatgatg ttattgtttt aaaaaaaaca taaaagcatt ataataatat
    32761 taacaaaata gaataaagag gaagagaata tgattataaa ggtttcaatg acagtattag
    32821 tattaatatt attgtatatt ctgtataagt atgaaactca gcatatagaa acgacagaat
    32881 atactatttt caacaaaaaa attccaaagg aatttgataa ctttaaaata gttcaagtga
    32941 gtgatttaca taataaggtg tttgataaaa ataataaggt attgatagat aaaattgaat
    33001 cattaaaccc agatgttata tttataacag gagatttagt agatggagaa aataaaaatt
    33061 ttcaagttgc attagattta atagataatt tggttgaaaa atatgaagta tatcatataa
    33121 ttggaaatca tgaacaaaaa tctttaataa aaaagtataa acatctatat aaggattatt
    33181 ttaaggaact atattcaaag aaaataataa atatggaaaa tgaatctgta agaatatata
    33241 gaggtaatag ccatcttaat ttatatggtt taattatacc attggaatgc tatccatatt
    33301 tatttgctaa taacaaaaaa ttagaactaa gtgacaattt tgtagaagac aatctaggta
    33361 aagttaatga aaatgaatat aacattcttt tagcacatac accatttttc tttgaaaaat
    33421 atgcaaaatg gggagcagat ttggttttag caggacatgt tcatggaggt ataataagaa
    33481 taccttttgt tggaggtgta ttatctccaa atagagagtt ctttcctaag tatgactggg
    33541 gaaaatatga aaaagataat agcactatga ttttaaataa aggcttagga ggctcaaaag
    33601 ttttaattag gcttaattgt aaaccagaga tagttaagat tacattgaag tatgagaaat
    33661 aagattttat ataacatata taaacatcaa taacatataa ataaggttga tgttaaatcc
    33721 atttaaacat atataatgac caattttgaa taattgttga attaataaaa ataaagtgct
    33781 atttttagca tagaatattt aaactatggg ggggagtaaa gaatcatggg tgatacaagt
    33841 agattttatg agtctgtaaa aaataaatat ccgaaattaa aagatggaac tagggttcat
    33901 ctgtggccaa aagaaaacat tataattggt cctatttatg atgaagaaga tggatataaa
    33961 aaaagtatcg gaaatgtgga tagcttaagt tggaagcaaa ttgttatact ggctgaatgt
    34021 gatgggaaaa atactactga cgatataata aatatattat ccaatagata tagaaatatc
    34081 cataatatga aagaaaaagt tatggaattt tttatgtttt atgagaatgt atacttaacg
    34141 tttgaagatg atatacagac actatcaagt gtatttgaga taacaggaaa taaatcatac
    34201 attactcctt tgtactttac tatagaaata gatggagata ataatacaaa tgattatttt
    34261 tctgaaatca caagtttatt gaactgcatg tatgagaaag gctgtagatt tatagaggtt
    34321 attggtgagg atattttaaa aaataaaagt atgagagaaa tatttcaata tatgttagac
    34381 cattttgatt taattgtggt aactaaagat agctttacta ttgatagaag cttaataaaa
    34441 gaattagata attatcgtca taaagtgata tggaaagtat attcaaaaaa tgatgataca
    34501 cgtattaaat taaaagaaga tataaaaata accagtttaa taaaaagggg tcacactgta
    34561 gtaagaggag acagagaaaa agcaataaaa atagaagata tgaggtttaa agatacaaag
    34621 gagaggtttt caaaatatgg agcagagtgg agtcatttat atatttcttc tgatggtagt
    34681 gtaaaatctt attcatttca aaaagataaa agagtctatt taggcaatat atttaacaat
    34741 tctgttgaag aaattttctt agagatgcaa aataaaattg acaaactaga aattgtgtat
    34801 caataagggt aaagtttaag atttatataa gatttataga ttgtttattt aagtttgtgt
    34861 caataattat aatgaggtga aatgacttgt taaaattatt ggacaaattt ttttatgatg
    34921 ttttacttaa attttggctg tttatgatgc tgtggatttt tagagaactt tttacaaatt
    34981 tcaaaatgac taaaaaattt aaatttcata aaatatttat gtaaaaatca tataaaattc
    35041 atatagcata tgtatcatat gaggtgtaga aagactagct taaaaaccat aatataatac
    35101 cctattgtaa tgataaccct ccctcacatc ctcaaataga gttatcatta caagaattaa
    35161 tccataaatt taaaatttat ggttttttt
//
LOCUS       DAEQJM010000036        35088 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.036, whole genome shotgun sequence.
ACCESSION   DAEQJM010000036 DAEQJM010000000
VERSION     DAEQJM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35088
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.036"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(72..845)
                     /locus_tag="KRQ43_002174"
     CDS             complement(72..845)
                     /locus_tag="KRQ43_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HBH2742529.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(845..1231)
                     /locus_tag="KRQ43_002175"
     CDS             complement(845..1231)
                     /locus_tag="KRQ43_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2742530.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1256..1573)
                     /locus_tag="KRQ43_002176"
     CDS             complement(1256..1573)
                     /locus_tag="KRQ43_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HBH2742531.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVKKIFTITGLDKIFK
                     VEG"
     gene            complement(1585..1845)
                     /locus_tag="KRQ43_002177"
     CDS             complement(1585..1845)
                     /locus_tag="KRQ43_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBH2742532.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1845..2141)
                     /locus_tag="KRQ43_002178"
     CDS             complement(1845..2141)
                     /locus_tag="KRQ43_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH2742533.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2210..4636)
                     /gene="gyrA"
                     /locus_tag="KRQ43_002179"
     CDS             complement(2210..4636)
                     /gene="gyrA"
                     /locus_tag="KRQ43_002179"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBH2742534.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDIAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKIGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKNEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4656..6557)
                     /gene="gyrB"
                     /locus_tag="KRQ43_002180"
     CDS             complement(4656..6557)
                     /gene="gyrB"
                     /locus_tag="KRQ43_002180"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBH2742535.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6558..7673)
                     /gene="recF"
                     /locus_tag="KRQ43_002181"
     CDS             complement(6558..7673)
                     /gene="recF"
                     /locus_tag="KRQ43_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBH2742536.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7691..7897)
                     /gene="yaaA"
                     /locus_tag="KRQ43_002182"
     CDS             complement(7691..7897)
                     /gene="yaaA"
                     /locus_tag="KRQ43_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBH2742537.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVKIEGTKIKVL"
     gene            complement(8034..9140)
                     /locus_tag="KRQ43_002183"
     CDS             complement(8034..9140)
                     /locus_tag="KRQ43_002183"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBH2742538.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9382..10704)
                     /gene="dnaA"
                     /locus_tag="KRQ43_002184"
     CDS             complement(9382..10704)
                     /gene="dnaA"
                     /locus_tag="KRQ43_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBH2742539.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11360..11497
                     /gene="rpmH"
                     /locus_tag="KRQ43_002185"
     CDS             11360..11497
                     /gene="rpmH"
                     /locus_tag="KRQ43_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBH2742540.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11575..11919
                     /gene="rnpA"
                     /locus_tag="KRQ43_002186"
     CDS             11575..11919
                     /gene="rnpA"
                     /locus_tag="KRQ43_002186"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBH2742541.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11951..12202
                     /gene="yidD"
                     /locus_tag="KRQ43_002187"
     CDS             11951..12202
                     /gene="yidD"
                     /locus_tag="KRQ43_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBH2742542.1"
                     /translation="MNKIIYILKEISRYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12234..12941
                     /locus_tag="KRQ43_002188"
     CDS             12234..12941
                     /locus_tag="KRQ43_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH2742543.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12910..13539
                     /locus_tag="KRQ43_002189"
     CDS             12910..13539
                     /locus_tag="KRQ43_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HBH2742544.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13651..15030
                     /gene="mnmE"
                     /locus_tag="KRQ43_002190"
     CDS             13651..15030
                     /gene="mnmE"
                     /locus_tag="KRQ43_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBH2742545.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGERALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNILDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKEIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15125..17020
                     /gene="mnmG"
                     /locus_tag="KRQ43_002191"
     CDS             15125..17020
                     /gene="mnmG"
                     /locus_tag="KRQ43_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBH2742546.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVDKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQVRR
                     TRGGKGE"
     gene            17013..17732
                     /gene="rsmG"
                     /locus_tag="KRQ43_002192"
     CDS             17013..17732
                     /gene="rsmG"
                     /locus_tag="KRQ43_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBH2742547.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGRPAKNPIK"
     gene            17907..18692
                     /gene="noc"
                     /locus_tag="KRQ43_002193"
     CDS             17907..18692
                     /gene="noc"
                     /locus_tag="KRQ43_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HBH2742548.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18827..19600
                     /locus_tag="KRQ43_002194"
     CDS             18827..19600
                     /locus_tag="KRQ43_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBH2742549.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19602..20465
                     /locus_tag="KRQ43_002195"
     CDS             19602..20465
                     /locus_tag="KRQ43_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBH2742550.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20498..21640
                     /locus_tag="KRQ43_002196"
     CDS             20498..21640
                     /locus_tag="KRQ43_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH2742551.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVSDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21774..22349)
                     /locus_tag="KRQ43_002197"
     CDS             complement(21774..22349)
                     /locus_tag="KRQ43_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HBH2742552.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDTSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22609..23901
                     /locus_tag="KRQ43_002198"
     CDS             22609..23901
                     /locus_tag="KRQ43_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH2742553.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24006..24608
                     /gene="yedF"
                     /locus_tag="KRQ43_002199"
     CDS             24006..24608
                     /gene="yedF"
                     /locus_tag="KRQ43_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBH2742554.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24681..24944
                     /locus_tag="KRQ43_002200"
     CDS             24681..24944
                     /locus_tag="KRQ43_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBH2742555.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24959..25144
                     /locus_tag="KRQ43_002201"
     CDS             24959..25144
                     /locus_tag="KRQ43_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBH2742556.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25247..26443
                     /locus_tag="KRQ43_002202"
     CDS             25247..26443
                     /locus_tag="KRQ43_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH2742557.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLEKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26657..26935
                     /locus_tag="KRQ43_002203"
     CDS             26657..26935
                     /locus_tag="KRQ43_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBH2742558.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            26972..27406
                     /gene="ssb"
                     /locus_tag="KRQ43_002204"
     CDS             26972..27406
                     /gene="ssb"
                     /locus_tag="KRQ43_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH2742559.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27425..27652
                     /locus_tag="KRQ43_002205"
     CDS             27425..27652
                     /locus_tag="KRQ43_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBH2742560.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27795..28115
                     /locus_tag="KRQ43_002206"
     CDS             27795..28115
                     /locus_tag="KRQ43_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH2742561.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28123..29079
                     /locus_tag="KRQ43_002207"
     CDS             28123..29079
                     /locus_tag="KRQ43_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HBH2742562.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29090..31084
                     /locus_tag="KRQ43_002208"
     CDS             29090..31084
                     /locus_tag="KRQ43_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBH2742563.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31085..31534
                     /locus_tag="KRQ43_002209"
     CDS             31085..31534
                     /locus_tag="KRQ43_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBH2742564.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31553..32881
                     /gene="dnaB"
                     /locus_tag="KRQ43_002210"
     CDS             31553..32881
                     /gene="dnaB"
                     /locus_tag="KRQ43_002210"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBH2742565.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33086..33394
                     /locus_tag="KRQ43_002211"
     CDS             33086..33394
                     /locus_tag="KRQ43_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742566.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33476..34765
                     /locus_tag="KRQ43_002212"
     CDS             33476..34765
                     /locus_tag="KRQ43_002212"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBH2742567.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNKIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
BASE COUNT        13291 a         4499 c         5555 g        11743 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata ccatctttaa aacagtaggt caatactttt
       61 tttatatttt tttataaatt tttttcatat tcttttttca gcttctctac tacctttttc
      121 tctagtctag aaacagtcat ctgtgatatc cctagttctt tagctatact agattgtgtt
      181 ttatcaaaga aaaatctatc tttaaaaatt ttaacttcta attcatttaa agtttcaata
      241 aacttattaa taaaatcttc atactctata cttccaaagt taccttcttc ttttccaatc
      301 ttatcaataa gagttatatc tttatcctct gaatcatcat tacttgatga atccaaagac
      361 attggttgat atccataaga agcctccata gcctctaaaa catcttcttc actaacgcct
      421 atataatcag ctatatcttt tacctttgga tgcttcttat tttcttgttc taatttaatc
      481 ttcgcatcac ttatcttttt gcttaattcc tgtattcttc ttgggactct aagtgtccat
      541 accttatctc taaaatactt ttttatttct cctactatag ttggtgtcgc aaagctggag
      601 aactcaaatc ctttctcaac atcatatcta tcaatagcat aaattaatgc caatgaagca
      661 acttgatata tatcttcaaa atcaacacct ttgtttatat acttcttagc taacaatctt
      721 gctaaataca gatgtctttc aataagaata tttctaatgt ctacattttt atttttatta
      781 tataaattaa atagctcttt tgtatccata tttaggtaat gtgtagcatt agctacattt
      841 ttcattaaat atcaactcct aaatatttag tcatttttat ttttgtccct tgattatgtt
      901 ctgattcaat atctacatca tccattaaag ttttaattat aaacaatcca agaccactct
      961 cttttggatt ctctaaatct ggtgtactta ttgagctaac atcatatcct tttccattat
     1021 cttgaatttc tatattaatt gcattatcta aaatattaaa tactatatta aacacatcat
     1081 ctttactgtg ttttattgca tttgtacatg cttcagatac tgctaccttt atatcttcta
     1141 tatcatctat tggaaaaccc atcttattgg caattccaga tgctgttaat cttattatac
     1201 taacataatc tggatttgta gtaatttcca tctttatagt ctcacaagcc aaagtttatc
     1261 cctccacttt aaatatttta tctagacctg ttatagtaaa aatctttttt acgttactct
     1321 taggatttac tatgtatatc tctttttcat ttatttttaa tttttttaat acacctatca
     1381 tagctcctaa gcctgttgag tctatataat ctaaatcttt aagattaatc tttacatcta
     1441 acatattttt ttctattaaa gcatgtaaat gttcctttag tttatctgct gtagaaacat
     1501 caagttctcc atcaagacaa acattccaaa atttattttg tgaatctaaa tttgaatcaa
     1561 tattcataga catgtaaaaa cctcctattt ccttttaata attttaaata tatttcctat
     1621 actcaatatt ttattaatta cataaactat atcatctatt ccctttgata ttgatgatgc
     1681 attttcaaca atatcttgta tatgtctttc attataatct acaatcttat atgccttttc
     1741 aacaacctta tttatgctgt ttagagtttt agctaaataa attgctacta taagagcaga
     1801 gcttcctact aacactgctc caatttgcca cccccatgca ttcattagtt aacatctccc
     1861 tcatcatcaa agcttttact tattactata tcttcttctg aaatctttat atcttcttca
     1921 ttattatcat cgtccactaa atttattatt ctctctttaa catcattaaa tgtttcatgt
     1981 agaacttctt ttggattttc tttgacatca ttaaacttct cttttgtttc ttttcttagt
     2041 tcagaacctt ttttaggtgc aaaaaacata ccaaatataa accctaaaat agctcctaat
     2101 aataaaaatc cacctttttt acaacttctt ttattgcaca taacaattac tcctttcaat
     2161 tttaaatttt tatctaacta cattatacaa aaagaatagg atatttatcc tattcttctt
     2221 caatatttat tttggcaatc gaaactacat tgacttcatc attcgtcttc attaatttaa
     2281 caccacttgt aactcttcca aacagtgata tttcattgac tcttattcta ataagaactc
     2341 catcagaatt tataatcatt atctcatcat cttcgttgac catatctgca cctacaattg
     2401 taccagtttt ttcagatata ttataagttt taattccttt accagctctt atttgacttc
     2461 tatactcttc tatatttgtt ctctttccaa aaccattctt acttacaact aacacatctg
     2521 tacctttact gcaaaggttc atagacacaa caaaatcttc tttacttaaa gttatacctt
     2581 ttacacccat tgctgttcta cccatatatc ttatatcatt ttcatcaaat cttatagaca
     2641 taccttcttt agttactaaa agtacttctt gttttccatc tgtaagttct actccaataa
     2701 gctcatcatc atctcttaaa cctatagcaa taagaccaga tttatttata tttttgaact
     2761 cttctctctt agtcttttta acaatacctt ttttcgttgc aagtaataaa tattcatttt
     2821 catcattacc atcaataggt attagagtag caattttctc atctgctgac aattgaagta
     2881 aattcactat agcagtacct ttagcctgtc tcttaccttc tggtatttca tatgcattta
     2941 atttaaatac tctaccttta tttgtaaaga ataatagtct actatgagta gttgtagtta
     3001 ccaagtgcct tacaaaatct tcttctctag ttgtaagtgc tgaaatacct cttccacccc
     3061 ttttttgact cttataagta tcagatggaa gcctttttat atatccaaag tgagtaagag
     3121 ttattgctat ttcttcatca cttataagat ctctcatatc tatttcgcct tcagcatgtc
     3181 ttatttctgt tcttctctca tcagagtaat tttcttttat tattgtaatt tcattcttta
     3241 ttacatttaa aagtaatctt tcatcagcta aaatttcttt taatctattt atcttcttga
     3301 ttaaatcttc atattcagct tctatcttat ctctttctaa acctgtaagt ctttgaagtc
     3361 tcatatctaa tatagcttgt gcttggattt cagttaattt gaatttttct attaaaccta
     3421 tcttagcttc ttgcccagtc tttgaagctc ttatcaagct tataacagca tctatattat
     3481 ctaaagcaat ctttaatcct tctaaaatat gtgctcttgc ttcagcttta tttagttcaa
     3541 atttagttct tcttgtaaca acatcttctt gatgtttaat ataatgatat aatatttgtt
     3601 taagatttaa aactcttggc tgaccatcta caagtgcaag cattattata ctaaaagtat
     3661 cttccatttg agaatgttta tacaaattat ttaatactat attagcatta gcatccctct
     3721 ttaattctat aacaattctc ataccatttc tattactttc gtctcttagg tctgatatac
     3781 cttctattct cttttcttta actaactctg ctattctttc aaccagttta gccttattta
     3841 cttgataagg tatttctgta actattattt gctgttttcc ttttggtagt tcttctataa
     3901 aagctctaga cctaacttta acttttcctc ttccagttct gtatgcttct gctatacttt
     3961 cttttcccat tataattgca gctgtaggga aatctggtcc ttgaacaaat tttattaaat
     4021 catctacact acactctgga ttatctatca aatatacagt tgcatcaatt acttctgcta
     4081 aattatgtgg aggtattgaa gttgccatac caacagctat accatttgag ccatttacta
     4141 ataaattagg atatctagct ggcaatactg aaggctcttt taacgactca tcaaagtttg
     4201 gtttaaagtc tacagtttcc ttttcaatat ctctcagtag ttctaatgat aatttactca
     4261 ttttagcttc tgtataacgc atagcagctg gtgaatcccc atcaacagaa ccaaagttac
     4321 catgaccatc tactaaaagt gctctagttg aaaaatcttg tgccattctt accatagcat
     4381 aataaacagc aatatctcca tgaggatggt acttacctaa aacgtcccca acaatacgag
     4441 ctgacttcct gtatggttta tctggagtta aatttaactc actcattgaa tataatattc
     4501 ttctatgaac tggctttaaa ccatctctaa catcaggaag agcacgtcca gctataacac
     4561 tcattgaata atcaatatac gattttttca tttcttccgc tatttcaata gggagtattt
     4621 tgttattttc ttccatgtat actaatcccc tctctctata tatctaaatt tctaacaaat
     4681 cttgcatttt cttctataaa ttcttttctt ggagcaacct tatcacccat aagcattgaa
     4741 aatacttcat ctgcaattgc agcatcttct acagtaactt gtaataaagt tcttgtctca
     4801 ggattcatag ttgtttccca taattgctct gcattcatct ctccaagacc tttgtacctt
     4861 tgaagttcaa caccatttct tccaatttca tctaataaga tatttaactc tttatctgag
     4921 taaacataat gttccttctt ttgctttgtc actttatata aaggtggctg tgctgcataa
     4981 acatacccct catctataag aggtctcata tatctaaaga agaatgttaa taataaagtt
     5041 cttatatggg ctccatctac atcagcatcg gtcataatta taattttatg atacctagcc
     5101 ttatctatat caaaatcttc tccaatacca caaccataag ctgttatcat attttttatt
     5161 tcatctgaag atagtatcct atctagtctt gatttctcaa cattaagtat tttccctctt
     5221 aatggaagta tagcttgact atttctatct ctaccttgtt tagctgaacc tcccgctgaa
     5281 tccccttcga ctaagaatat ttcactttta gatggatctt tttctgcaca atctgcaagt
     5341 tttccaggta aagatgtact ttctaataca ctttttctcc ttgttaattc tcttgctttt
     5401 tttgcagctt ctctagctct ttgtgctctt aaagctttat caactatgat tcttgctgtt
     5461 gatgggtttt cttctaggaa agaccccagt tcatcaactg ttacactatc aactatacct
     5521 ctcataaagc tattacctag ctttgtttta gtttgacctt caaattgagg ttctggtaat
     5581 ttaactgata ctactgctgt aagaccttct cttatgtctt caccaagtag gttaacatca
     5641 ttttccttta aaaatttatt tctcttagca taatcattta cagttttagt aagagctgct
     5701 ttaaatccac ttaaatgaga accaccttcg tgtgtattta tattgtttgc aaaagaatat
     5761 atgttctctg tataaccatc tgtatattgc atagctagtt caacaaaaca atcatcaacc
     5821 tttttatcta tataaactat gtcatcatgt ataccagttc tagatttatt taaatactta
     5881 atatattcta ccaaaccacc tgtatagtga aattcttttc ttttttcttg tccttctctt
     5941 ttatcttcaa atactatttt tattccttta ttcaagaaag aaagttctct aagcctatac
     6001 tccaatgttt catatttaaa ctctatttca tcaaatattg tctcatctgg cataaattga
     6061 atcattgttc ctttatcttg agattctcca actacttcaa gcttagatgt tggtaatcct
     6121 ttctcatatg tctgcttata tatctttccg tttaaataaa cctctgctac catccatttt
     6181 gacaatgcat taactacaga aacaccaact ccatgaagac ctccagatac tttatatcct
     6241 ccgcctccaa actttcctcc tgcatgaaga ttagttaata ctgtttctaa agttgattta
     6301 ccagttttag gatgtatttc aacaggtata cctcttccgt tatcttttac taaaacactg
     6361 ccatcttcat taatagatac atatatgtct gaacaatatc cttgtaaagc ctcatctata
     6421 ctattatcta caacttcata aactaagtga tgtaaacctc tagggcttgt actaccaata
     6481 tacatacctg gtctttttct aacggcttct aatccctcta atacttgtat ctgacttgca
     6541 ccgtattctt gtttcattta atttcctcca ttctctatgc taataacatc gccattttca
     6601 atattaaata ttgtaacatt tttttcatca aatatttttt tatgtgaaac ttcagcactt
     6661 gttataaaca tttgaacatt gcttaaatta tttactaaaa gtttttgtct tgcttcatct
     6721 aactcactaa aaacatcatc taaaattaat actggatatt cttcaacttc attttttatt
     6781 aattctatct ctgataactt taatgatatt gaagcagttc tttgttgacc ttgtgaacca
     6841 aaaagtcttg catctaaatc atttatgaat atatttaagt catctttgtg tataccatat
     6901 ctggtagtct tagattctat atcattaggt ctattcgatg acaacttggc taaaaattta
     6961 ttatatactg tatctatagt atcttcatca gttatattta tttgattttt atatcgaatt
     7021 gataatcttt caactccatt agtcaaattc atatgcatat tttcagatat attagctatc
     7081 ttttttataa agtctctacg caaaatataa atataacttc catactttgc taacgtatca
     7141 tcatatacat ctaataaagc ttcatcaaca tgtatatttt taagcaccct actcctttga
     7201 gaaagtgttt tattataatt ggtaagatat ttataatatt taggtataat ctgactaatc
     7261 tctttgtcta taaatgccct tctttcttta ggaccctctt taaccaacct taaatcttca
     7321 ggagaaaata taacaacatt taagttgcca agtagttctt gtatcttttg taaaggaact
     7381 ttatttattc ttatcccctt tttatctttt ccaataatta gctctattag actatattta
     7441 ttatattttg aaaaacttcc tccaatgtat aagttttcac tattaaatct aaccatttct
     7501 ttatctttgt tagtcctaaa tgattttcca aaagaaagca tataaataga ttctactata
     7561 tttgtctttc cttgaccatt tttaccaaca agtagattta ctttcccatt aaattccaga
     7621 tgcaactttt tataatttct aaaattaaca agttgcaaac ttttaagttt cacaaaaagt
     7681 tctccttttt ttacaatact tttattttag ttccttctat tttaactata tctcctgatt
     7741 ttatcttttt tcctcttctt aattctattt catcatttac tgtcactaaa ccttcttgaa
     7801 ttaaaaattt tgcatgacct cctgttgatg caatctctgc taatttaaga aattgatcca
     7861 actttatata ttctgattct atagttattt cagtcataat agttcctcct tgtcactatt
     7921 ttaaacaaat tcctattgat acactaaaag tatattatac cataaatatg cttataaaag
     7981 gagttgtcta agattagaaa aattttctac aaaagacaac tccttcatgt ctgctatata
     8041 tttgatgata ttcttactgg aagcagtaag taaatataat taacatcatc tgttggttta
     8101 attatacaag gatttacatt tgtagtaaat tctataaata tttcctcatt atctatattt
     8161 ttcaaacctt cgataaaata tctagaattg aaagctatat ctaggtaatc tccatctaaa
     8221 tctatttcaa cttcttcata cacatttcct ttttctgtgt tagaagtaat tgccattact
     8281 ttatctctta tagataactt tataagatta tttttttctg attgagacaa taaagacgct
     8341 ctctctatac tatttaaaag ttccttagtg tttaatttaa ctctgctgtt atgttctctt
     8401 ggcaataatt ttttataatc aataaaatct ccttcaagca atcttgtaat aattttcgta
     8461 tcattaatta taaaaatagc atttttttcg ttaaacccaa ctttaacatt atcctctcca
     8521 gaaagcaaac tatttacatc tataagtgtc tttccaggaa ttatgacttt tatattttca
     8581 gttaaactat caactgaaca actttttaca gctaatctat atccatcaat tgctactaaa
     8641 tttaagtttc tatctacaat ttctaaaagt tctcccatta aaacaggttt tgtttggtcc
     8701 tgtgagatag caaatacagt ttgtttaatc atatttttta gaatttcttg aggtatgcta
     8761 tataaatctt cttcatttaa ttctggtaat ttaggaaatt cttttgctgc ataaccttta
     8821 attttaaatc ttgaatttac acaatttatg taaatattat tttctgaatc agtttctatc
     8881 tcaacaaagg aatctggtaa ttttctaatt atatctccaa atagccttgc atctacaaca
     8941 acatcacctt tttctatgat ttctgcttgt acataagttt ctattcctat ttcagcatca
     9001 tatccagtaa gttttaattg accttcttct gtagatataa gtataccttt taataattct
     9061 attgttgttt ttccattaat agctttttga gcaattccaa ttctatttgc taggattttt
     9121 tgattacaaa ttattttcaa tgtggataac ctcctctggc tttttatata taaaaataag
     9181 ttaaaatcat agtagtaata gtagtaggtg ttgttgataa tgttaataag tatgtataac
     9241 attataaata caaagatatt aacatgtgta taagatgtta atatctttgt tattttagac
     9301 ttgataattt gttaataatt tttgttcaaa aaaagtatta acaggttatt caagagatat
     9361 aaacatacaa ttgtgtataa attatccctt caaatctgat ataattttgt ctattttagt
     9421 cttaatttct tcactttctt ctatatcctt agatactttg tcatgagcat gaattactgt
     9481 tgtatggtct ctacccccaa actcttcacc tattttagga agggataaat cagtaagctc
     9541 gcgcgttaaa tacatagcta tctgtcttgg ataagctatt gaacgtgttc tttttttaga
     9601 attaaaatct tccatcttta aattgaatac agaagatact ttttctttta ttctaagaac
     9661 atttatttct tcatttttag aagttgttat aatatctttt aaagcttctg tagcaagatc
     9721 aaaagatatt accctattgc taagagaaga ataagcaacc actctagtta atgcaccttc
     9781 tagttccctt atgtttgact taatattttt tgctatatat gacataacct catttggcac
     9841 atctatacgt tctagttgag ccttttttct aagtatagca attcttgtct caaagtcagg
     9901 tgcttgaata tcagttataa gtcccatttc aaatctcgat cttagcctat cttctagtgt
     9961 aggtatgtct tttggcggtc tatcactaga tataattatt tgtttgtttg cttcatgaag
    10021 agtattgaat gtatggaaaa actcttcttg agttctttct tttcctgcta taaattgaat
    10081 atcgtcgatt agtaatacat ctacgtttct atatttattc ctaaattctt cgtttttatc
    10141 gtcttttata gagtttataa gttcattagt aaatttttct gaagaaacgt aaactacttt
    10201 tgagtctttt ttttgactaa caatatgatg acctatagca tgcattaggt gagtcttacc
    10261 taatccaact cctccataca aaaaaagtgg gttataagct ttagctggag attctgcaac
    10321 tgcaacgcat gcagcatgtg caaatctatt gctattacca ataacgaatg tatcaaatgt
    10381 gtattttgga tttagattgg ggtaaagaac tctataattt aaatctgtgc tatcagaatt
    10441 taaatcagca acctcttttt cgctcaatac aaatttaata ttatattttt ttaatgacag
    10501 ttgactaata gcatcttcaa ttaaatgtaa atatctattc tctaagatat ctttattaaa
    10561 atcactagga gccagtaaga ttaaatcatt aagatgtatt tttaatggta cgatgttttt
    10621 aaaaaaggta ttaaaactta ctgaagttaa gtcacctttt attaattgta gggttttgtc
    10681 ccataaagaa actatatcca taatataaac ctccgaacag aataattaat attttccaca
    10741 aagttattaa cagaaaagca aaaatatata taaattttac agaataacta aatttatgga
    10801 taatggtgtt gataaattaa taatagtata aattattaaa aaaatatgaa aagatataaa
    10861 caatatgtag ataaagttat aaataacata aacatacaat aaatggtgat tataactaga
    10921 gtattgtcag taatcttaaa agttatacac aaaagtatcc acaagctgtg aataatttct
    10981 aataagttga taacatttat gcacattatc aacaagtata tttataatat caaaatatat
    11041 gtcaaacttc aatgatttgt aactaattta tccacaatat taactaattg ttgataaaaa
    11101 tataaacatg ttaaaattac tttatttgtg tatataattg aaaaaaataa tttagaataa
    11161 aattaaatag atttttgcta gtattttcaa taaaaaaaat acataatata tatatggtag
    11221 attttgtgat ataagcgtcc caaaaactcg ttgacaacag tagtaaaagt atttataatt
    11281 atatgtgtta tgtttacttt gagggtaaag ttattatttt tataaacgga aaataaaatc
    11341 tgaaaggcgg tgcaaaataa tgagtaaaag aacttatcaa ccaaaaaaga gacaaagaag
    11401 taaagaacat ggtttcagaa aaagaatgaa gacgtctaac ggaagaaacg tgttaaagag
    11461 aagaagagct aaaggaagaa atagattaac tcattaatta caaaagggcc gctgcaaagg
    11521 tggccttttt gtgtaaataa ttacaattca tagctgtgtt tatggaggtt aactatggac
    11581 tttaatagga ctaaagggtt gaaaaaagac tctgatttta gaaaagtata taaacacggc
    11641 aaatcttttg caaacaaata tttagtaata tatatactta aaaataaatc agattatagt
    11701 agagtaggta tttctgtttc aaaaaaagta ggaaaagcta ttactaggaa tagagtaaga
    11761 agattaataa aagaagccta cagattaaat attgatgaaa aaattaagcc tggatatgat
    11821 atagtattta tagcaagggt atctagtaag gatgctactt ttaaagacat agacaagtct
    11881 ataaaaaatt tagttaaaag aacggatatt tctatttaat tgtatgctat aaatatggag
    11941 gttaatgact ttgaataaaa taatttatat attaaaggaa ataagtaggt atttatcgaa
    12001 tttatgtatt tatttagtga gattttatca aaagtatata tctcccttaa agggacctac
    12061 ctgtagattt tatccaactt gctcacaata ttcaatagag gcgtttaaaa aatatggatt
    12121 tgtaaaaggt atgtatttaa cgataagaag acttttaaaa tgtcatcctt ttcatccagg
    12181 aggttacgac cctctaaaat aaaagagagt aactattagg aggtataaaa aaattgaata
    12241 taataggaaa tttcttagga ttgattctta aggtaatatt tgaatttgtt aatcattatg
    12301 gtatttctat aatacttttt acgatacttg taaagattat tttattacca ttaacaatta
    12361 agcagactaa gtcaacaaag gcaatgcaag atatacaacc tcgtataaaa gagatacaag
    12421 aaaaatataa aaataagcca gaaaaacaaa atgaagaaat tgttaagtta tatggagaag
    12481 ctaaaattaa tccactatct ggttgtttac ctttattaat acagtttcct atattaatag
    12541 gattatttag cgttttgaga gaaccagttg ctcatggcgt ttttgcaaac aaagctgcat
    12601 ttttagcagc tgacaatggg tttttatgga taaaaagctt aacatcacca gattatgtat
    12661 tagcagtatt ttcaggagca agtgcatatg tcatgcaaaa agtaatgaca cccaaagatc
    12721 agttacaagg ctctatgaaa gtaatgacat atgtaatggc aggtatgtct ttctattggg
    12781 gatttatatt cccagcagga cttacattgt actggacagt aagtaactta ttctcaatag
    12841 ctcaatatta cttaataatg aatcctttaa aagctaaact ggctgctaac tctaaggagg
    12901 aaaaagttaa tgagaaaaag cctaaaatta ataaaaagta agagtaaaga ggaagctata
    12961 agtaaagcta tagcagagtt gaatttaaaa gcagaggata tagaagtaga aatacttgaa
    13021 aatccaagta aagggttttt aggttttata ggtgctaaag atggtactta tgaaattttt
    13081 gttatcgaga gggaagtaga tgtagctaaa aattttatag aggtaatgtt gaaaaatgca
    13141 aatgttgatg ccaaagtcaa tgtatctcaa aaagataatt taatcatggt tgatattgaa
    13201 ggcaaagaag ctgcaagttt aattggtaga agaggggaaa ctttagattc tattcaattt
    13261 ttgactggat tagctcttaa taaaataaat aaagattctc atacaagagt acttgtagat
    13321 atagaaaatt atagatcaaa acgagaagaa tctttaataa gatatgctaa taaagttgct
    13381 agagaagtag cgaaaacaag aaaaactaaa aaattagatt atatgaatcc atatgagaga
    13441 agaataatac attcagctct tcaaaatgac aaatatgtaa ttacatatag tgaaggaacc
    13501 gatccatata gaagattagt aattgagtgt aaaagataaa gtcaacctcc taaacattag
    13561 ggggttttat tttttaatat tattaaatca ttaatgattg gttaaatgta aacctatatg
    13621 taaaaaatta tgaattaaga ggtgataaat ttgtttatag atgatacaat tgcagcaata
    13681 gctacagcac ctggagaagg tggtataggt atacttagaa taagtggaga aagagctttg
    13741 aaggttgcag aagaaatctt taaatctatg tcgggaaaga gtattgaaga atacaataag
    13801 agaacattaa tatatggaaa tatattggat aatgaaaata taattgatga agttttattg
    13861 gcatatatga aaggaccaaa ctcctataca ggagaagatg ttatagaaat taattgtcat
    13921 ggtggattta tttcggtaaa gaagatatta gaattaatac tatcaaaaga tgttagatta
    13981 gcagaggctg gtgagtttac taaaagagca ttcttaaatg gaagaataga tttatctcaa
    14041 gcagaggctg taattgatgt tataaaagcc aaaactgata tagctcatga agttgctcaa
    14101 aatcaattag agggttcttt atcaaagaag ataagagaat tgagagataa agtcactgag
    14161 atattagctc atgtagaagt tgctatagat tatcctgagg aagatattga gcatataaca
    14221 tatcaaactc ttaaagaaaa aactgatgaa cttaaaaaag agattaaaaa attatatgat
    14281 acagctgaaa gtggaaaaat acttagagaa ggcttaaaga cggtaattgt tgggaaacca
    14341 aatgtaggta aatcttcact acttaattct attttaggag agaatagagc aatagttact
    14401 gatataccag gaactactag agatgttata gaagagtttg taaacataaa aggtatacct
    14461 ttaaaaattg ttgacacagc aggtataagg gatactgatg atatcgttga aaaaataggt
    14521 gttgaaaagt ctaaagaatc atttactagt gcagatttga tagtaatggt tttagatgca
    14581 tctagaaagt tgtcagagga agatatagag atattagaaa aacttaagga taaacaaaca
    14641 atagtgctgt taaataagaa tgatttgaaa caagagattg aagaagaaaa aatacttaaa
    14701 tatgtagaaa ataatagtat aataaaaata tcagctttac aacaagaagg aatagaagaa
    14761 ttgcaagata aaatagagtc tatggtatat aaaggtagta tcaaaaataa ttctagttta
    14821 gtagtaacaa attcaagaca taaagatgca cttagtaaag catataaatc tgcaacagat
    14881 gctttaattg ctttggaaca aagtatgcca tttgactttg tagaagtcga tttaaaaaat
    14941 atatgggact atcttggata tattaatggt gatacagtaa cagaggattt actagataat
    15001 atattccata atttctgtat tggtaagtaa tgtacaaaag taaatttgtt tttattatag
    15061 agatttttaa aaaatttgaa gtgtttctca tgaaacatta attttgaaaa gaaaggaatt
    15121 ataaatgata aagtttgaag caggaaaata tgatgttata gtagtcggag caggacatgc
    15181 tggatgtgaa gctgctttgg ctactgcaag aatgggatat aaaactttga taataacaat
    15241 gtctttggat tccatagcat taatgccttg taatccatca attggaggga ctggtaaagg
    15301 tcaattagtt aaagaaatag atgccttagg tggtcagatg ggattaaata tagacaagac
    15361 atatatacaa agtagaatgt taaatactgc caaaggtcca gcggtacact ctttaagagc
    15421 acaagcagat aaatttaaat atcatgaaga aatgaaaaag acattagaag atgaaccaaa
    15481 tcttgatata gctatggatg aagttgtaga aatacttcat gaaggaaatg ttgtaatagg
    15541 agttggaact aaactaggat gttcatttaa atctaaagct gtaatattgg ccactggagt
    15601 ttatctgaac tcaaagatat atatgggtga agttgcattt tatgaaggtc ctaatgcatt
    15661 ggggtatgca aaatatctta cagatagctt agttgagctt ggtcttagaa tgagaagatt
    15721 taagacggga actccagcaa gagttcatag agatagtata gacttctctg taatgtcttt
    15781 acaagagggc gatgaaaaag taactccatt ctcatttatg aatgaaaata tagaaaaaaa
    15841 acaagaacct tgttatttaa caagaactac agaagaaact caaaaagtta tactggataa
    15901 tttaaaaagg tctgctatgt atagtggagt aatagaaagt actggtccaa gatactgtcc
    15961 ttctatagaa gataaagtag taagatttag tgataaaacc tcacatcaat tatttataga
    16021 accagaaggg ttaaatacta aagaaatgta tatacaagga atttcaacta gtttaccttt
    16081 tgaagttcaa ttagatatgt acaaaactat aaagggactt gaaaattgta agataatgag
    16141 acctgcatat gctattgaat atgattgtgt tgacccaact caactaaaaa taagtttgga
    16201 aataaagggt gtcgagaact tatttagtgc agggcaattt aatggaactt ctggatatga
    16261 ggaagcagca gctcaagggc ttatggctgg tataaatgca gttagaaaga tagaaggaaa
    16321 agagccgttt gtattagacc gttcagaagc ttatataggt gtcttattag atgaccttgt
    16381 tactaaagga actaacgagc cttacagaat gatgacatca agagcagaat atcgactata
    16441 tttaagacaa gataatgcag atatgagatt aactcaaaaa ggttatgata taggattagt
    16501 taaaaaagat agatatgaaa ggttcctaaa taaaaaggct gctgtagata aagaatttga
    16561 aagattaaaa aatgaaagag ttacaccaaa agaagtaaat agtttgttag aagaaaaagg
    16621 agcaacacca ataaaggttg gaatatctct atatgaattt ttaaagagac cagaggttac
    16681 ttacgaattg cttgaagaat tagggaaggg cgctggagaa gatgtttcaa gagaagttaa
    16741 agaacagtgt gtaataataa ctaaatatga aggttatata gagaaacaat tgaaacaaat
    16801 agaccaattt aaaaaacttg agaataaaaa gctggatgag aaaataaatt attcatctat
    16861 agaaggtctt agattagagg ctagacagaa attagatgat ataaaaccta tttcaatagg
    16921 gcaagcatct cgtatatcgg gtgtttctcc agctgatata tcagttttac ttatatacct
    16981 agaacaagtc agaagaacta gaggtggcaa aggtgaataa tatagaactt ctgaaaaacg
    17041 ggattgaagg ttttaatata gatacgaatg acagtatgtt agaaaaattt aaaatctata
    17101 gagagatatt agttgaatgg aataaaaaga tgaatcttac tggaatagaa gatgaaaaag
    17161 aagtgtatat aaaacatttt ttagactcta tttcagctgt aaagaatgga tatataaaaa
    17221 atgggatgtc tataatagat gttggtacag gtgctggttt tcctggaata ccattgaaaa
    17281 tatgtttaga tagcttagaa cttactttgt tagattcgtt aaataaaaga ataaactttt
    17341 tagaggaagt tagtagagta ctagagttag ataatattac atttatacat ggaagagctg
    17401 aagattttgg taaaaatgaa gactatagag aaaaatatga tgttgctacg gcaagagctg
    17461 ttgctggatt accgattctt atggaatttt gtgtaccatt tgtaaaagtt ggagggtatt
    17521 ttatttgctt aaaaggtccg aatgctaatt tagagctaga agaatcacaa aaggctattg
    17581 atgttttagg attggagtat attgaaaaaa tagatgtaga gttaccagag gtagatttaa
    17641 atcataatat attagttttt aaaaaggtga tggaaacacc agttaagtac cctagaaaag
    17701 ctggtagacc agctaaaaat cctattaagt aatgaaaaaa gtaatgaaaa aattattatt
    17761 ggtaagctta attatttctt aggaaataat taagcttacc gtaaaaaaac aaaaataaag
    17821 gaattattaa agtagatgca gaaataaatt tgtatgtaca tatagagaac aaaaataatt
    17881 tatatctaaa ataagagagg tatgttatgg aagataaaag agttatggag atacctatag
    17941 aagatgtagt tccaaatcca tatcaaccaa gaaaaatatt ttcacaagtt tcattggagg
    18001 aattgagcaa ttctataaag gtatatggta taattcaacc tataacagtt agagcaaaag
    18061 atggcaaata tgaactaatt gcaggagaaa gaagattaag agcagctaaa ttagcagagc
    18121 ttaaaaccat accagcaatt ataaataata tgaatgatga atcttctgct gttctagcgt
    18181 tattagaaaa tttgcaacga gaagacttaa atttcattga agaagcaatt ggttatgaaa
    18241 acttaataaa agaacatgct tttactcaac agcaattagc agaaaaattg ggcaaaaatc
    18301 aatctactgt agcaaataag cttagaatat taaagcttcc aaacgatata aaaatgaagc
    18361 taatagagaa taatttaaca gaaagacatg ctagagcatt tcttaaacta ccaagtgaag
    18421 atttaatgca aagtgtgtta gacaaagtca taaaaaatga attgactgtt aaaaaaacag
    18481 aaaaattgat acaagatgta ttagaagaaa ctaaagttca agaagagcct gataaaaaac
    18541 agaatataaa gggtgctatg agtataagaa tttacataaa tactataaag caggcctttg
    18601 atgctatatc aaatacagga attgatgcta agtataatga aatagataag ggagattata
    18661 tggaagttgt tgtgaaaatc cctaaaaaat agagattact gcttaccagt aatctttttt
    18721 tgtaatataa gccttgtaat ataaattgat ttatagacat tatttatact taaaaaacac
    18781 ctattcaaca tttaaaatta atttaattct taaagggggg aacatcatgg gcaaagttat
    18841 agctgtattc aatcaaaagg gtggagtcgg gaaaactaca acaaatgtaa atttaagtgc
    18901 tagcttagga actttgggaa agaaaatatt agtattagat ttagacccac aaggaaatac
    18961 aactagtgga tatggtatta ataaaaacga agtagaaaat acaatctatg aaattatgtt
    19021 agatgggtta catattaaag aagcaataat aagtactgaa tttgagaatg tagatgtagt
    19081 tccatcagct actgaactat caggtgcaga gatagagctt acatctaaaa ctaatagaga
    19141 gtatatttta aaaaattcca taaaagcggt aatagatgaa tatgattata tatttttaga
    19201 ttgtccaccc tcactgggga tgcttacaat aaattgttta actgctgtag atagtgtttt
    19261 aattccaata caatgtgaat attatgcttt agaaggtgtt agtcaattaa tggagactat
    19321 aaaattagta aaatcaagat taaatgctga tatagaaatt caaggtgttg ttttaagtat
    19381 gtttgatgga agagctaatt tatcaataca agtagttgaa gaagttaaga aatactttaa
    19441 aggtagtgta tatacaactt taattccaag aaatgtaaga cttgcagaag ctccaagtca
    19501 tggaaaacct gtaatttatt atgataaaag atgtagaggg tctgtagctt atttggagct
    19561 agcagaagaa tttatagatt tagaagagga ggaatggtag tatggagaat aagtctaaaa
    19621 gaagtaatag attaggtaga ggtcttagtg cattgatacc agaaattaaa ggagaaactt
    19681 cagaaaaaga aatagtcaac atagatatag acaaaatata tccaaacgaa gttcaaccta
    19741 gaaagcaatt tgatgaagaa aagataaaag tattgtcgga ctctataaaa aattatggtg
    19801 ttttacagcc aatagtggtt aaaatggatg aaaataataa atatatgata atagctggag
    19861 aaagaagatt tagagcatca aaacttgcaa ataaaaatca aatacctgct ataattaaag
    19921 atatagatat gaaagatata atggagatag ccttaattga aaacttacag agggaagatt
    19981 taaattcaat agaagaggct ctagcatata agagtttaat agagcattac aatgtaactc
    20041 aggaagaaat atcagaagct gttgggaaga gtagacctca tataactaat acactaagac
    20101 ttttaaatct tggacaagat gttatagaaa tgatagacag tggtagaatt acagcaggcc
    20161 atggtaaggc tttattgaga attgcagata aagatttgca acttcaaata gcgaaaaaga
    20221 tagaagaaga agaactttct gtaagagaag tcgaaaatat agctaaaaaa atatctgaaa
    20281 ataaacaaga agaacctaaa aaatctaaac ctaaggatgt atttatttta gatgttgaag
    20341 ataaacttag aaatatattt ggaacaaagg tgaatatttc taaaggaaag aagaaaggta
    20401 aaatagagat agaatactat aatgatgatg atttaaatag tattgtatca atgcttcttg
    20461 aatagaacaa aaatataaaa cagagaggaa gattgttatg atttatttag ataatgctgc
    20521 aactacatat ccaaaaccag aaagagtgta taatgctgtt ttagattgta tgaaaaatta
    20581 ttgtgcaaat ccaggtagag caggccataa acttgctatg agagctgcta gggagatata
    20641 tgatacaaga gagaatatag ctaagttgtt caatgtaagt aatcctatga atatagtatt
    20701 tacatctaat gcaacagatt ctttaaattt agcgataaaa ggtgtattac aagaaggaga
    20761 ccatgtaata acaacgtcta tggagcataa ttcagtaata agacctataa aagcattgga
    20821 aaaaaggggt attgaaaata ctgtagtaaa atgcgattat gagggatttt tagattatga
    20881 agatttagaa aaatcaataa agagtaatac taaactgatt gtaacaacac acgcatctaa
    20941 tgtatgtgga actttaatag atataaaaaa agttggagaa atagctaaaa aacataatat
    21001 actattttta gtagatgcat cacaaacagc aggtgtttat gatatagacg taaatgaatg
    21061 taatatagat atgttggcaa tgccaggtca taaatgctta tttgggcctc aaggaacagg
    21121 tatattatat gtaagagaag ggttgaactt aaatatatta aaagaaggtg gaacaggtag
    21181 taaatcagaa gaaatagttc aaccagagtt attcccagat aagtatgaat caggaactca
    21241 taatactcca ggtatagcag gtcttaacca aggtatacta tttatatttg aaagaggaat
    21301 caacaatata agacaacatg aagaagaatt atgtcaatat atgatagaca aactagagga
    21361 agtatcagat ataaagatat atggaccaaa ggatagtaaa aaaagagcat cagtaatcgc
    21421 tctaaatata ggagatatgg attctggaga ggttactttc ttattagata gtgattataa
    21481 tatagcaact agatcaggaa tacattgttc accactagca cataccactt taggtacttt
    21541 aaaacaaggt gcagtaaggt tcagtatagg atatttcaac acaaaagatg agatagataa
    21601 agcagtggaa gctttgaaaa aaatttcaaa aaataaatag catgagattt aataatatag
    21661 aaataaaaaa aggggatatt tcaaaataaa aatttgaatc atctcctttt ttgtacaaaa
    21721 aagaaaaggg gctcctaaga acctctaatc tatttgataa ttgtttcaag aaattacttt
    21781 aagtaatctc cttcttcaag aactatatga ccactttcgt aattagaacc atcaacagta
    21841 atttttattt gttcaacatt catatttttt atgtaagtac gagcaactga atcaagcatt
    21901 aaagtttctg catcactacc taagtttgac tttgtaaagt cagagctaac atctaatata
    21961 ccagttttta caccatcaat gtcttttgta gtaaatgaat ttaattttgc agattctgga
    22021 acaactttaa gtttttgaag ttcttcaaat aaagtgttct catcaatttt atttaaatca
    22081 actttatttt caattaaatc tgtcttatct acatcaaaag agtaaatagt agctgattga
    22141 gttttagttt cttcttttgg agtaggttta gctttgttat taggaacctc tttttcagta
    22201 ttgttttctt cttttggttg ttcaacattt gtattgctct tagtttcttt tttagatgta
    22261 tcacttccat tttgagcatt agtacaacca actgcgaata tagatataga taatatactt
    22321 aacactaaca ttattttctt atttttcata aaaatttctc ctctcttaaa aactattctt
    22381 atatataatt atagtcgtta tgagcaaata tatgaataca aaatagtaac aaatttaaaa
    22441 aatgatttat ttaaattaat aaaactcaaa ataaactaaa ttttagtcat ttttatggga
    22501 aatcatttaa tgtacagtga aaatattgta aaataaaagt agtgttttta aaataaatat
    22561 aagttataat tatattataa aaaaatgtct tcaaaaggtg ggaatagtat ggaaattttg
    22621 agcttaggag aaaagattaa aaaattaaga aaagaaaaaa acatgacatt aaaagaatta
    22681 gctggagata ggataacagc agcacaaata agccatatag agagggataa atctcatact
    22741 agttatgaac tgttggaata tctaggcgat aagctagatg taagtgtaga atacttatta
    22801 gagaccaagg aaatgcaatc aaaaaagata actgataatt taatactaca gagcgaaatt
    22861 tatataaaag aaaatgaatt aaacaaggct gaggatcaaa taaaagaagt tttagatata
    22921 tgtaagagat acgatttaat ggagaactat ggcagatgta attttttaat ggctaatatt
    22981 aatttgaaaa aatctaatta taatgatgct atagaaaact ttgaaaaggc attgtacttc
    23041 tttataaaaa atagtgatag tgaaaatata cttaagtgtt atttaaacat agggaaaata
    23101 tatatgcagg aagactttta taaaggtgct ataagccact ttaattttgc agaggaaatt
    23161 ttgtcagaga ataaatttga ggatgttaac atacacaagg aactatatag taagatggca
    23221 tattgttaca taaaactaga taatccaaat atgtcattga agtacataga aaagataaat
    23281 gaaatagata atagaaatga tagaaaagaa gatgtcgata ttttggtgtt aaaagcaaat
    23341 aatatgcttg agattggaaa atatgaagaa tcaagagatt actttaaaaa agcactaaaa
    23401 atacttgaga gtgaggataa taaaactgga ttagcaaatg tgtatttaac aatttgtgat
    23461 gtttacagaa aaataggtga aacagataga gtacttgaat attcacaaaa ggtatatgac
    23521 ataaagaaaa atgatgaaga tgaatacatg atgtcaggat tatttaagat aatagaagca
    23581 tatatagata aagaagatta tgatttagct agaaaatatt gtaagatagc cttagcttca
    23641 tcaataaaaa ataaaaataa attcaatgaa tataaagcat tgagattcta tgctaatatg
    23701 tataaaaatc agaatgaagt aactcttgca attgaatatc tgattaaatg cataaaaata
    23761 gtatcagatt taggcaacaa tagaatattg gccaatttat atatagactt aggtcaatta
    23821 tattcaaata tatcaaaaga aaaagagtta gaatattatc aaaaaggtgt atttatgtac
    23881 aaaaatttag aaataatgta gggtaaataa acctataagg gtatagaaac aatctataac
    23941 aagcaagata atatctatga taaaatataa attgtatgaa tatttttaag gagatgaatc
    24001 agacaatgag tataaaaata gatgcgagag ggcttgcttg tcctaaacca gttataaata
    24061 caaaaagaga attggataac ctagaagaag gtgttgtagt tacaatagtt gataatgaaa
    24121 cagctaagga gaatatatta aaacttgcta aatctttaag ttgtgaagca aatattgttg
    24181 acgaaaaaga gaattttata tctatagaaa ttagaaaagg taaaaatata ctagataaac
    24241 aaaatgttgt agataataaa gaaagtgaat tagacaatac atgtatattt atatcttcag
    24301 ataagatggg acttggaaat gacgaattag gaaaagtgtt aataaaagga tttatatata
    24361 cattaacaga atctaaacct tatcctaagt atgtactttt agttaatgga ggagtaaaat
    24421 taagtgctga aaatgaagaa accatagaaa atctaaaaat acttgagaat atgggtgtag
    24481 aagttttatc ttgtggtact tgtttagatt attataattt aaaagacaaa ttacaagtag
    24541 gtacagttac aaatatgtat actatagttg agacattaaa gaatgcatca aataccattt
    24601 ctatataatg tatgtttgtt taataatata aaactaataa taaagattaa ctcaaataga
    24661 tagtcagaaa ggattaagta atgaatcaaa tgtatatagt gtcatttaat tcgacacatc
    24721 atgcgataag atcagaaaag ttatttggtg aaaatagtct aaaagtaatg gctcttccaa
    24781 caccaagaga aataacagca agttgtggaa tatcaattaa attttctttt gaagatatgg
    24841 aaaagataaa aactattttg gttgaaaata atgtagatat aaaaggaatt tattgtataa
    24901 gtaaattaga aaatggttca aaagaagtag agaagttaga ttaggaggct aattatttat
    24961 gccaatggat ttaaaaatag gtgatattgt tgaattaaaa aagcaacatg catgtgggtg
    25021 taaagagttt gaaatcataa gaacgggaat ggatataaag ataaaatgta ctaaatgttc
    25081 aaggctaata atgcttgata gagagacctt agaaaagaga gtaaaaaagc taataaaaaa
    25141 gtgataaaaa tttaacactt aaaaaatgtc aaataccgta tattaatatc caaaattttg
    25201 gtataataag aattgaagaa aacattttca tgggggtgct ttaattatgg cagttaaata
    25261 tgcaaaaaga atgcaaggat tacaaggatc agaaatacgt gagcttttaa aacttactca
    25321 acaaccacaa ataatatctt ttgctggtgg aatgccggct ccagagttat ttccagttga
    25381 ggaaatgaaa aaagtatcag ttgcagtgct tgaagaaaat ggaagatcag ctatgcaata
    25441 tactacaaca gaaggatatg aaccattaag agaaaaaata gcagctagaa tgaatgataa
    25501 aaacaaaact aatgtaaaca aagatgatat attagttaca agtggttctc aacaaggtct
    25561 agattttgca ggaaaagtat ttattgatga gggtgatgta attttatgtg aaagtccatc
    25621 ttacatagga gctataaacg catttaaatc ttatcaacct aaattcatag atgttccaac
    25681 agattctgat ggaatgataa tggaagaatt agaaaagata ctagaaacaa ctgatagaat
    25741 aaaaatgatt tacgtaatac ctgacttcca aaatccaaca ggaagaactt ggccacttga
    25801 aagacgtaaa aaattcatgg aaatagtaaa taaatttgaa ataccagtaa tagaagataa
    25861 tccatatgga gatttaagat ttgaaggaga gactttacca tctttaaaat caatggatac
    25921 aaaaggatta gtaatattct taggaacttt ctctaaaata ttctgcccag gatacagatt
    25981 aggatggact tgtgcttctc cagaaatttt atctaaattt aactttgcaa aacaaggtgc
    26041 agacttacaa gcatcaacta tatctcaaat ggaagtaagc aaatttatgg atatgtatga
    26101 cctagatgca catgttgaca aaataaaagc agtttatgtt aaacgtagag atgtaatgct
    26161 taagactatg gaagaagagt tcccagaagg attagtattt actcatccag aaggtggatt
    26221 atttacatgg gtagagcttc caagtaattt aaatgctaaa gaattaatgc caaaatgttt
    26281 agagaagaat gttgcttatg ttgctggagg aggattcttc cctaatggtg gtagagaaaa
    26341 tactttcaga cttaactatt caaatatgcc agaagaaaaa ataatagaag gtataaaaaa
    26401 tatagcagct gtattaaaag aagctatggg tgtagaagct taattaaaaa taataactta
    26461 tatataatac aagggatggt tgttgccatc ccttgtttgt ttgaaaagta tataattcac
    26521 cttatactaa actttgtcca aaatttaaat tgacagaaat aagaataaat gataaaatgt
    26581 gtaggtatga gattttagtc tcatttctct gctctaagag tgtagagccg ttaagtccaa
    26641 agggaggtga attatagtga gaaattatga attagtttat gtggtaaagc caaattctga
    26701 tgaagaagta agagaggcta tactaaacaa agttaaggaa gttgttgcaa ctgacggaga
    26761 aatagttaaa gttgatactt ggggaactaa aaaattagct tatccaatag ctaagtttac
    26821 agaaggtttc tatgtattag ttaacttcaa atcagcagta gacgttccta aagagataga
    26881 cagaaactta aagataaatg aaaacgtaat aagacacatg atagttgttg cttaataact
    26941 ggttttatta taaaaaatag gtggtgtttt tatgaatcaa gttgtattag tgggaaggtt
    27001 gactagagac cctgaattaa gatacatccc aggtacagga acaccagtgg catcctttac
    27061 aatagccatt gatagagact atgtaaaaaa agatggatct aaagaaactg attttatacc
    27121 tgttgaagta atggggaaat ctgctgaatt ttgtgctaac tacataacta aaggtagatt
    27181 agtagcactt caaggatcta taagagtaga caattatcag acacaatcag gtgaaaagag
    27241 aacttttaca aaagtaagta ctagatcagt acaagctttg gatagtaaaa ataaatcgga
    27301 aaattcatat agagagagtg ctccagcttt tgagccaagc tttgaacctc aaggtttaga
    27361 cccacaaggt tttcaagcta tagatgatga cgatatacca ttttaaaaag gagggaaaaa
    27421 agtcatgatg aataagaaaa gacgtaagaa aaaaagagtt tgtcaatttt gtgctgacaa
    27481 aaacgctaaa atagattaca aaagtactca aagattacaa aagtatataa ctgaaagagg
    27541 aaagatatta ccaagaagaa tatctggaac ttgtgctaag catcaaagag aattaacagt
    27601 tgctataaaa agagcgagaa atatagcact tttaccatat acattagact aaaaaaatga
    27661 gccttgtgct cattttttat tatatgtatt tatatatcta aatgaggcga gctataaagc
    27721 tcgttttttt gtttatatac ttaaatatat tattatttat gatataatat tatatattaa
    27781 ggagggttgt aaacgtgaaa atagataaag gttctgagat aacgagaaac ataaagataa
    27841 tagaatggat gaaaacagaa atattaatga gtgtaagtga tttgtttaat ttattgttta
    27901 aaggggtaaa accattagat gaagcaattc aagatacttt agcaaatata ataatgataa
    27961 catatctctt agcaaagaga ttaggaatta gttttagaga tgtggattat aaagtcaagg
    28021 aaaaaataaa aattggtata gatgaggacc atagcgttga aagatggtat ggagatttat
    28081 ctaatttaaa aaaacatatg gataataggg agtgatatta aattgaataa taaaattaga
    28141 ctatctaagg caatgtctat aatagtttta gctataataa tcgctttagt aatagcctat
    28201 attccaatgc taggaatatt tagtatgtta gcagctgttc catatgtaat tataggtgct
    28261 attactgata gaaagtattc tcttatatct attttggtta cattttgtgt actgattcta
    28321 tttgcagaca tttcttatgc attaaatata tgtataatgt attctttacc aggtatagta
    28381 ataggaaaga tgctaaagag aagctttgaa caagaggaca gtaataaatt cgaaccgata
    28441 tatggtggaa ccataatatt tgtactttca atgcttgtat atttttttgt attaaagaca
    28501 tttttaaatg tgaatctatt agatgaagtt tctaagatga tatcagaaat tgtaaatatt
    28561 caaaaaaata gtttttctgc aactgaactt aaagtgtttg ataaaatgaa gccagatgag
    28621 attgtaagtt attttacaaa tatgctacca atgatgttat ttttacaagg gttgttatca
    28681 gcgtttgtca catattattt gagtgtattt tttataaaaa ggattacaaa gatgaatata
    28741 agatttccta aatttgctga tttttattta ccaggaaatg ctatactcac aactttctta
    28801 ctttatttat tagtcttatt tattcaaatt attggttcaa aattatatac agaattaata
    28861 atgactaatt tacagctagt ttttaattta atgtttgtaa ttcaaggtat agcagtttgc
    28921 atttatttct taaagaaatg gataagacag ggaccaaata aaattatgtt tttttcaggg
    28981 ataattttat gtttatttgg atttatggga atatcttttg ttggtatggt agatagtata
    29041 attgacttta gaaaggtaag aagctataaa tccacttagg aggatagaaa tgagtaacaa
    29101 acaaaccttt aaattaaata tgccagaaat aaatttatat ataattgtta ttggtatttc
    29161 tagtataatt ttgctttatt acaacttgta tgtagggtgt ttatttttct gtatttttgt
    29221 atatatggtt tttcacaatt ggagaactac taatattaga cgtcatgaat ggacagagta
    29281 tattcaaaat ttatctttag atatagatga aacaactaaa aaagccataa taaatcttcc
    29341 aataccatta tgtattttag aatttgatgg aaatatatcc tggtataatg gaaagtttta
    29401 tgatatgatt ggtcaaaaag atttacttga taaaaatata gaggatatag ttaaaaatct
    29461 taatttaaga aaagtattaa atgaaaataa agagatgtac acagaaataa actataaaga
    29521 aaaagaatat acaataattt ataatgttat aaaaaatgat caagaaaaaa atcctaaata
    29581 tttgatgata ttatactgga tagacaagac tgaatattta aaagtaaaac aaaattatga
    29641 tgatgaaaaa aatgcaatga tgctaataca agtagatgga tatgatgaag tattaaaaag
    29701 tgcagcagaa gataagagag ctttaattaa tgttgaagta gagaaaatac tttctgcttt
    29761 agaattaaat tcaaatggtg cattgagaag aacttcaaaa gacaaattct tcttggtaat
    29821 gcataaaaaa gagctaaaaa aattggaagc tgagaagttt tctattttag atacaataag
    29881 acatattgat tatggaaata atcttcctgt tactataagt ataggaattg gtatagatgg
    29941 agatacatta aatgagaacc taaaacttgc tacgggtgct ctcgatttag cacttggtag
    30001 aggtggtgat caggctgttg taaaaacaaa agataaattt gtgttttatg gaggaaaatc
    30061 taaagctgta gaaaagaaaa ccaaagtaaa atccagatta ataggtcatg ctttaagaga
    30121 ggttatacaa caaagtgacc aagtttatat aatggggcat aaatatcctg atatggatgc
    30181 tatgggagca gcagttggtg tttatgatat atgtaaatcc tgtaacaaaa ctgcaaacat
    30241 agttttacaa tctgtaaatg aatctataga aatatttata aataaaataa atgaaaataa
    30301 ttactataaa aagctgttta ttggaaaaga ggaagctatt gacaactgta ctaaaaatac
    30361 attagttgta gtagttgata ctcatagacc aaattatact gaatgtgaag aactgttaaa
    30421 gctatcagag aaggtagtag ttatagacca tcatagaaga ggtgtggagt ttataaatga
    30481 tgcagtgctt ttattccatg agatatatgt atcctcaacg tgtgaaatgg ttacagagtt
    30541 agttcagtat atggatgaag atgtaacaat aaataaactt acagctgaag ggcttttagc
    30601 aggtataagt ctagatacta aaaactttgc attcaaaaca ggtgttagga cttttgaagc
    30661 tgcttcttac cttagaaaag ttggagcaga tactatagag gtaaagaaat tcttcaattc
    30721 tgatgtaaaa gatttcataa taaaagctga aataattcaa agtactaaaa taattaataa
    30781 tagaatatgt ttagcatatt caagtactga gatagatagt ataaatgtta taatagctca
    30841 aactgctgat gagttattaa atatcaaaga agtagaagct tcctttgtat taggtgaaaa
    30901 agatgatact atatttataa gtgcgaggtc tttagggcaa ataaatgtac atgtacttat
    30961 ggaaaaatta ggaggcgggg gacacataga tatagctgga gcacagttaa aaaatgtttc
    31021 tctaaaagaa gcttataaga tggtaaataa aataatagag gagtatttgg aggaggaaga
    31081 atagatgaaa gttatattat taaaagacgt aaaaggaact ggtaaaaagg gagaaatgaa
    31141 agaagtaagt gatggatatg caagaaattt cttatttcct aaaaagatgg ctgtgcaagc
    31201 agatagtgta gcaataaaag aattaaatga aaagaataaa tctaaagaaa taaaagcaca
    31261 aaaagagtat gaagaagcag ttttattagg taagcaaatg gaagaaatta atatagaaat
    31321 atattcaaaa gcaggagaag gtggaagatt atttggttca ataacttcta aagaaattgc
    31381 tgagcaatta aagaaacaaa aagacataga cgtagataaa agaaaaatat tattagatga
    31441 accaataaga tctttaggtt caactttcgt agaaataaaa atacatcaaa aagtaactac
    31501 taaaataaga gtggatgtaa aagaaaaaca gtaataacta gaggtgatta agatggaaga
    31561 tatgacgaga attcctcctc atagtgtaga atcagaacaa tcaatattgg gttctatact
    31621 tctagataaa gatgctataa taacggttac agaaactata aagcctgatg atttctataa
    31681 agaggctcac aaaataatat atgaatgtat gataacttta agtaataaag gtgagcctat
    31741 agacttgata acattaacag aagaactaag aaaacaaggg catcttaatg atattggagg
    31801 aatcagttat attacaagtc tttctactat agtaccgacg acttcaaatg taaaatacta
    31861 tgctgatata gtaaaagaaa agtctgtact tagaaagctt ataaaagctt ctaatgaaat
    31921 aataaatcta ggatatagtg gagcaactaa gattgaagat gttttagaac aagctgaaaa
    31981 gagtatattt gatatatcac aggagaaaac tagtgatgat tttaaatcta taaacttagt
    32041 tttgatggat gcctatgata tgatagaaaa attatatact aacaagagtg atgtcactgg
    32101 tataactact ggttttaaag atttaaacaa aaaaataaat ggtcttcaaa ggactgattt
    32161 aatattaatt gcagctagac cagcaatggg taaaactgcc ttttctttaa acttggttca
    32221 aaatgcagcc ttaaaaggtg atgcctctgt agctgtattt agcttagaga tgtctaagga
    32281 acaattagta caacgtatgt tatcttcaca atctagtgta gaattaaaaa aaataaagac
    32341 tggaacactt aatgataatg attggcctag aattatagat gctatggcag tattatcaga
    32401 tgccaaaata cacatagatg atactcctgg tataaaaata tcagaactaa ggtcaaagtg
    32461 tagaaagtta aaaatagaaa aaggactaga tttagtgctt attgattatc ttcaacttat
    32521 ggaaggtgaa ggtaataatg aaagcagaca acaagagata tctaagatat caaggtcact
    32581 aaaaatatta gcaaaagaat taaactgtcc tgtagttgca ctatctcagt tatcacgtgc
    32641 accagaacaa agagcagacc atagacctat gttatctgat ttaagagagt ctggagcaat
    32701 agaacaggat gcagatatag ttatgttctt atacagggac gaatattatc atgctgattc
    32761 tgagagtaaa aatataggag aagtaataat agcaaaaaat agacacggtg aaactggttc
    32821 tgtggaactt gtttggcttg gtgaagttca aagatttggg gataagttga gagacctata
    32881 atctaacgaa tatccacaga acgtcctttc tttctacagg aaaaatgtgg atacatgtca
    32941 ctaaatatgt ccaaacattg aaatttagct aaaaaactat ccacactatc cacagatagc
    33001 ctgttgataa gtgtgaataa gtagataaag caagcttttg gcttgcttta tctgtgtata
    33061 aatattaatt attaggagga ataatatgga aaaaataagc ttaaaatata tatatcccaa
    33121 tataattaaa gtacttgatg aaataaactt atttagagta attgacaata atttaagaga
    33181 gtctattgtt gtttatgcta ataatgtgga taatcagtat catataaaca tgactaatac
    33241 aaactttgga aacataatta acatatgtaa attagaaaaa cttttagatg tggataaatt
    33301 tatggaaaaa gttataaaat atgaaaaaga aataatagag aaagaagagt tttcaaaaat
    33361 agaagaatat atgttaaata ttggagaata ctaaaaaagt tgaaaaaaat acgaatgttt
    33421 gatagaataa gtaagtaaag tgttcgagag tatataaaat atagaggtga attacatgaa
    33481 aacagttgca attgttggtt ctcaatgggg agatgaaggt aaaggtaaag ttatagatta
    33541 tcttgctact caagcagatg tagtagtaag agggcaaggt ggaaataatg caggacatac
    33601 attagttgta gaaggtaaaa aatacgcatt acatctaatt ccatctggag ttttaaatcc
    33661 aaatacagtg aatataatcg gaaatggaat agtgtttgac cctaaaggat ttttagaaga
    33721 attggaaatg tttaaaacgg ataatataag tacagaaaat ataaaaataa gtgatagagc
    33781 acatgtcata ttcccatatc ataaagaact agatgcattg tcagaagaag ccagaggcga
    33841 tttaaagata ggtacaacaa aaaaaggtat tggaccttgt tatatggata aaacagagag
    33901 atctggtatt agaatatgtg acttaatgga taaagataaa tttgctataa aattaaaagc
    33961 tcaaatagat gctaaaaata aaatagttaa aaatatatat ggaaaagaag aattatttga
    34021 ttttgaaact atatataacg aatatctagg atatgcagaa caaataagaa aatatgtggc
    34081 agatacgtct gttattgtat atgatgcagt aagagcaggt aaaaaagtat tgtttgaagg
    34141 agcacaaggg actttattag atttagattt aggaacttat ccatttgtta catcttctca
    34201 tccaacatct ggtggatttg caattggtgc aggtatagga ccaaatatga taaaagacgt
    34261 tgttggtata gtaaaagcat atactacaag agttggagaa ggaccgtttg ttacagagca
    34321 aataaatgaa actggagata agataagaga acaaggacat gaatttgggg taactactgg
    34381 tagaccaaga agatgtgggt ggtttgatgc agttatagtt aagtatgcag ctagagttaa
    34441 tggattgact agtatttcat ttatgttact tgatgtatta actggatttg ataagataaa
    34501 agtttgtacg tcttataaaa tgggcgataa gataataacg gatttcccag cttcattaga
    34561 tgatttagca aaatgtgaac ctgtatatga agaattagat ggatggaatg aagatataac
    34621 tcaaatagat aactttgatg accttccaga aaatgcaaag aaatatgtag caaaaataga
    34681 agaactagtt ggagtaagtg tagatatggt ttctgttggt ccaaatagag ctcaaactat
    34741 aataagaaga aatatatttg cttaatattt tatcaattaa ataatttaaa atagttgaag
    34801 aagagtatct caagataatg tttatagtta ttagagatgc tcttttatat ttgacttaca
    34861 ttgatttttt attaagttaa agctacttat acatattcta gctgaaatta aagttgaatt
    34921 tatgtagata catataggtt ttttaaaaag aattttgttg aaaataaatg gctaaagatg
    34981 attttaatta tattctaaaa aaagtaaaaa aaactattga ctaaaaattg tatagacgct
    35041 ataatataac ttgtgagtga aagaaacgac gaaaaaagtc gaaaaaat
//
LOCUS       DAEQJM010000037        35018 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.037, whole genome shotgun sequence.
ACCESSION   DAEQJM010000037 DAEQJM010000000
VERSION     DAEQJM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35018
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.037"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(64..264)
                     /locus_tag="KRQ43_002213"
     CDS             complement(64..264)
                     /locus_tag="KRQ43_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2742568.1"
                     /translation="MPKFICNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(266..616)
                     /locus_tag="KRQ43_002214"
     CDS             complement(266..616)
                     /locus_tag="KRQ43_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBH2742569.1"
                     /translation="MIQKKIFMGFCGFLGFLSLRYFSSGNVTDLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNVELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            778..966
                     /locus_tag="KRQ43_002215"
     CDS             778..966
                     /locus_tag="KRQ43_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH2742570.1"
                     /translation="MTKYDFNFKLKVAKFYLNREGRDILIVKQYGVYDHSQVERWVNI
                     LGEGALKIKKFSILYGSS"
     gene            complement(1442..1592)
                     /locus_tag="KRQ43_002216"
                     /pseudo
     CDS             complement(1442..1592)
                     /locus_tag="KRQ43_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1989..2483)
                     /locus_tag="KRQ43_002217"
     CDS             complement(1989..2483)
                     /locus_tag="KRQ43_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH2742571.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIIALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKNDYGNLIDITNDQNKINIVIKLLNN
                     KSNT"
     gene            3289..3666
                     /locus_tag="KRQ43_002218"
     CDS             3289..3666
                     /locus_tag="KRQ43_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH2742572.1"
                     /translation="MKEEILIEKLLRAELIVMEYLCKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINFQYHYKIIIDNKEYYTFKKKVLKSSKSIKIMRSLT
                     TTHKNVSKEKLDLLDEYYRNLKE"
     gene            3771..4146
                     /locus_tag="KRQ43_002219"
                     /pseudo
     CDS             3771..4146
                     /locus_tag="KRQ43_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            4758..5450
                     /locus_tag="KRQ43_002220"
     CDS             4758..5450
                     /locus_tag="KRQ43_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742573.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            5646..7706
                     /locus_tag="KRQ43_002221"
     CDS             5646..7706
                     /locus_tag="KRQ43_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBH2742574.1"
                     /translation="MEKYRALKLVSLIIISISFPLTILLATIGLAEPKYNIQKTSTKS
                     GIFNISNDFYDSNIFDEGTVESLLSNFKISVDSQLTSEEKSKLQTKSKSIDLSSNDSE
                     YDKIMINKQASEEYLSYLKNIKVYVINTYTGVFYTNTSYGNLDDFKQKTKSYCNIEII
                     NNVGKSSYIKTINGEKFELNNLSMELNGVDEAFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVACLSLAIVCLLSIILYSRIKGEVLKRNNVFLLIYSKIPMEFNVILVF
                     ISIAILTMYALAVSYHIDVIVLVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYIKVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(7912..8235)
                     /locus_tag="KRQ43_002222"
     CDS             complement(7912..8235)
                     /locus_tag="KRQ43_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBH2742575.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(8228..8929)
                     /locus_tag="KRQ43_002223"
     CDS             complement(8228..8929)
                     /locus_tag="KRQ43_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBH2742576.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(9207..10592)
                     /locus_tag="KRQ43_002224"
     CDS             complement(9207..10592)
                     /locus_tag="KRQ43_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH2742577.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(10700..11938)
                     /locus_tag="KRQ43_002225"
     CDS             complement(10700..11938)
                     /locus_tag="KRQ43_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH2742578.1"
                     /translation="MELFIEVIKFNIYISLLILFFILFTKKISKYTFKFNYFICLLIV
                     VRMMFISKINLNILNINNTTINIYKHNLDNYIPYDQGITLDIFMYIWILGIIAISFYY
                     LRTNFKFYNYIENFKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTR
                     CKIIIPEKKYNNKELRFIFKHELIHYKRKDNLFKLLISIICIIHWFNPILYLLKKYFH
                     ELCELSCDEIVIDKCTTSEIKEYAYIILNTIKYQKTLKYSSFVSQFLNKKNIILKKRL
                     NSMFNQDKKKINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIAKINYNKNGETYGT
                     HIIDSNGNSIEPELIQTIGRGKKVGYVKKRDLYDCDNQPKTPEEAVLYTRKRNFNIFK
                     KTIPLYDKEGIKIIGRFEIN"
     gene            complement(11951..12319)
                     /locus_tag="KRQ43_002226"
     CDS             complement(11951..12319)
                     /locus_tag="KRQ43_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH2742579.1"
                     /translation="MKKIPKSELLVMNFIWDKGIDKIPAREVANYMEISHGWTKGTTG
                     KVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISSLGC
                     GNEISDDDIKELEQWLKKRK"
     gene            complement(12847..13269)
                     /locus_tag="KRQ43_002227"
     CDS             complement(12847..13269)
                     /locus_tag="KRQ43_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBH2742580.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            13747..16650
                     /locus_tag="KRQ43_002228"
     CDS             13747..16650
                     /locus_tag="KRQ43_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2742581.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILVL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     ISIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIVTLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            16683..17129
                     /locus_tag="KRQ43_002229"
     CDS             16683..17129
                     /locus_tag="KRQ43_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2742582.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            17252..17554
                     /locus_tag="KRQ43_002230"
     CDS             17252..17554
                     /locus_tag="KRQ43_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742583.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            17735..19141
                     /locus_tag="KRQ43_002231"
     CDS             17735..19141
                     /locus_tag="KRQ43_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH2742584.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFSDPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVISMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            19485..20543
                     /locus_tag="KRQ43_002232"
     CDS             19485..20543
                     /locus_tag="KRQ43_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH2742585.1"
                     /translation="MGDKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYASPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            20618..21304
                     /gene="araD"
                     /locus_tag="KRQ43_002233"
     CDS             20618..21304
                     /gene="araD"
                     /locus_tag="KRQ43_002233"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBH2742586.1"
                     /translation="MLEILKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNVVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            21322..21969
                     /locus_tag="KRQ43_002234"
     CDS             21322..21969
                     /locus_tag="KRQ43_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH2742587.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GIGREELNVEHICVLDLNGNVIEVEKGIKPSSEVLMHIEIYKIRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFESWKYPEEIKF"
     gene            complement(22142..23509)
                     /locus_tag="KRQ43_002235"
     CDS             complement(22142..23509)
                     /locus_tag="KRQ43_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBH2742588.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLRSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(23699..23787)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            24215..26335
                     /locus_tag="KRQ43_002236"
     CDS             24215..26335
                     /locus_tag="KRQ43_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBH2742589.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESILKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNKLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKEIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            26439..27692
                     /locus_tag="KRQ43_002237"
     CDS             26439..27692
                     /locus_tag="KRQ43_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBH2742590.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFEDIETYSKDSQKKREKEL
                     DKFINTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEIYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTQV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGFMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(27846..28907)
                     /gene="ytvI"
                     /locus_tag="KRQ43_002238"
     CDS             complement(27846..28907)
                     /gene="ytvI"
                     /locus_tag="KRQ43_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH2742591.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLSLILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFLELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFIGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            29181..29921
                     /locus_tag="KRQ43_002239"
     CDS             29181..29921
                     /locus_tag="KRQ43_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HBH2742592.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            29933..31711
                     /locus_tag="KRQ43_002240"
     CDS             29933..31711
                     /locus_tag="KRQ43_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH2742593.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRILEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            31878..32795
                     /gene="pfkB"
                     /locus_tag="KRQ43_002241"
     CDS             31878..32795
                     /gene="pfkB"
                     /locus_tag="KRQ43_002241"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH2742594.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYAKRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            32832..34751
                     /locus_tag="KRQ43_002242"
     CDS             32832..34751
                     /locus_tag="KRQ43_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2742595.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT        13897 a         3847 c         5498 g        11776 t
ORIGIN      
        1 caggagtgac ttaaagattg aatttaagtt tgtatttaaa acacattttt aataatgcaa
       61 aaactaatca aaaataaaca attcatcaat aggtgtatct actatttttg atatatctat
      121 tgctaatttc aaagaaggat tatactttcc tgcttctaaa cgcataatgg tttctcttct
      181 aactcctact ttttctgcta attgttcttg agttaattct tttaattgtc tatatttttt
      241 taggttacaa atgaatttgg gcatattatt tttcctctaa aatataaagt tttatagcat
      301 aaacatttaa agtgattgca tatgtaattg atagtaaaac acacattaat tctacattcc
      361 tagacactat agtaatacac cataaaatga ataattctat aatagcaagc tgtcctgtaa
      421 atgccatagc tgctttttca tcttgtacat acctttcatc tgctttatca ccatttattt
      481 ttgctataat aaagtttgag aaaaaagcaa aaaatccaat atatgtaaga tcagtaacat
      541 tgccagatga aaaatatcta agacttaaaa atccaaggaa accacaaaaa cccataaaaa
      601 tttttttttg aatcattttt tatcctcctt agtaatttta aaagagatat atttgtatct
      661 ttataataca aatatatctc ttttatattc ttttgtcaat agaaaatcag tattatacaa
      721 tatttgtact gcaccataat tgttagagta aaaatctaac gcttgagatg tttatgtatg
      781 actaaatatg attttaattt caaattaaaa gtagctaaat tttatttgaa tagagaagga
      841 agagatattt taatagtaaa acaatatgga gtttatgacc attctcaagt tgaaagatgg
      901 gttaatatat taggagaggg tgcactaaaa ataaaaaagt tttctatact atatggttca
      961 agttagatgt tataaactat atgatgataa ctaagtatag tgtacaataa atcgctaagt
     1021 attttggaat aaacaatagc acagttatag caacatgaaa acaaaaattt ttacatagtg
     1081 gtgttgatgc ctttttcaaa atgaaaggaa gaccataatg aataaaaaca aaaacactaa
     1141 agaaaaaata aattaacaag agaacaagaa ttagaatatg aaaataaatt tttaaaagat
     1201 gagcttgagt ttttaaaaaa gatgtgtgcc tcagggaagc cacattaaaa atagtggtat
     1261 cattattaat caaaagaaag ttagatgtat tatcaaaaaa ttagaactta aatgcatagc
     1321 attttttcat aaatcacata aatataactc ctataaaggt acaattggaa aagtaaaaaa
     1381 taataaaata aatagaagat ttaaaacatc aatagcatat cagaaaataa caaatgatat
     1441 gctagaattt ataaaatata tctaattata aaaaaggcat atctcgattc attttttgtt
     1501 atattgtcaa ataagaatac tatagatgaa agatacgatt ttgcagatgt attaagtaag
     1561 tattctgatg tttttggttg atacacatgc aataaagaag ttgtgtttgc agataaatta
     1621 gcaaaactat agtataagtt gcaacaataa agagaatgaa aattatcata ctaaagcata
     1681 agacatgtta caattttatt agataggaca ttaacataca ctaaagtact ttttattata
     1741 aagagtgctt atttttttga aattcattaa tgtataaact atcaagaata ttactcaaca
     1801 caatttaaaa acaacttaaa taggtatttt tagcaacata aattatgtga tataataaaa
     1861 aatagaagtg tatgccaata cacttctgta gttataacta agcattctat tcttggggag
     1921 tgcttttttc atttctccaa acaagattgt ttatttcatc agtaattatt aaatcaaatt
     1981 tattgtattt aagtattcga tttattattt aaaagtttta ttacaatatt tattttattt
     2041 tgatcgttcg ttatgtctat taaatttcca taatcatttt ttaatttatc tagaccactt
     2101 ttgcttattt ctccttctgg aagtatgctt aattctagat atttttcatg accaggagat
     2161 gacattaaca gatatgaacc attataaggc atccctaaat tttctatttt atctgctaat
     2221 gggtcatctt taaaaccccc atttattatt atttttccat ctttctttac ccatgatatc
     2281 attcctccat cagtatactt ggattcatca gcatagtaac taagagatgc actttttatt
     2341 gcacttatat cagcttcaag tttagctatc tttgcttttt ctatattttt aaataatgct
     2401 ggaagtgcta ttattgccaa tattcctatt atagcaatta ctactaataa ttccactaga
     2461 gtaaatcctt ttttattttt catttatttc ccctccatat aaaattaata atatataaat
     2521 ttttattttg ttgatttcta ctttctatat tttaccatat atagacaaaa aaatcacttt
     2581 ctatgacaaa tatactatta ttttacaatt tatagaaatg atttaaaatg acatttcttg
     2641 ttagaaaaga tataagcaat ggattaaaat aaagaaaact acagtcatat caatgtcaat
     2701 aatattattt aaaagcagat gaaaataaaa agaggaccca gaaaataatg tctatttaat
     2761 tatacttact taccaatacc ataacttgat ataaacaaga ttatactaca ttttttttat
     2821 gctctattat aaaatcatct aactgtgtat ctataaaatc aaaataatta tatgaattat
     2881 cagtataata agtcaaaata tgtatacatg aatacatatt tttaaaagat atatattatt
     2941 acatacctaa aaaactttca taaaaacaaa aataaaatat gcttttagta acttgttaac
     3001 ataacttata atttatttta taagcattag cctatatagt tttgtgctac taaatttctt
     3061 tgattctaac gatttagtgc tattctacaa ctaaaataat acaatagagc tatttattgt
     3121 ttggtagcat tgtttgcaaa ttaaacaaat atatatatat gaatattatt ttacgtttaa
     3181 aaaaacagac taaatatgta gaatatttgg taaaacttac ctctagtttt tgtcttaaaa
     3241 agctcctatt attaatttaa gttagaagaa ttaaggaagt gacataaatt gaaagaagaa
     3301 atattaatag aaaaattatt aagagcagaa ttaatagtaa tggagtattt atgtaaaaaa
     3361 gacactctaa tgcctaaaaa agaaattgta aaagaaataa aacagattta tggatggcat
     3421 aaaagtacaa taaaaatact actaaaaagg ctagttgcta aaaggtattt ggctagatat
     3481 attataaatt ttcaatatca ttataaaata ataatagata ataaagaata ttatactttt
     3541 aagaaaaagg tactaaaatc tagtaaaagc ataaaaataa tgcgttcact taccactaca
     3601 cataaaaatg taagtaaaga gaagttagac ctattagatg agtattatag aaatttaaaa
     3661 gaatgatata gtaaaaatcg aatgtaatta tttaccttaa ttcttttgtt tgtaaaactt
     3721 tattgatata gaatttaaca tatacataaa ttggtaaagg gatgtatact atgaaaatta
     3781 gtaaattacc agaagcggaa ttaaaagtta tgagatatat ttgggaatca gaaaaggtat
     3841 taatatcaag agaaatcacc aagtctatgg aacaaaaata tgaatggaaa gatacaacta
     3901 tatttacagt attaaaaaga ttactaaaga agagagtttt tagaaacgga gaaaatagat
     3961 aagcgtacac actataatgt attagtaaaa gaaaaataat atcagagatt ttaaacaaaa
     4021 gaatttttaa agaatacaca taaaaattca atattaagtt taatgtcagc actatgtagt
     4081 aaggatgatg aagtagatgg tgatatttta aatttattag aagaatattt taagaattta
     4141 aaataagaaa atgacagcta gatacataat aaataaaatg aaggtatgaa attataactt
     4201 tttctacatt cattttgttt attattctga acatgttaaa aaaatgaaat aagtttgtat
     4261 tttatttata taaattttaa tagaatatgt acagtatata gtagatagaa tgtataaaaa
     4321 tagaatttaa ataagtagct attattgcag tgaaataaat gtttctaagt atatttgggt
     4381 ggaagaatgg tggaagaaaa ttagtgaaat gtaattcttc caccattctt ccaccccaaa
     4441 aataaaaact gttcaataag aattaatata cattaattca gctgaatcca atcaaaatac
     4501 ttaaataaaa gtaatctgaa aataacataa ttcaaatcaa tttattcaaa taaatctcaa
     4561 tttatcttaa atcttaagaa atatttaaga attaggataa tattttctta agatttatat
     4621 tttattatat agttataagg gaaagttaca aaaatgtaag ccaaagtaat ataacaattt
     4681 agtcattgtt gagaaagtaa gtgaaagata ttgtataata tagataagta ttattataca
     4741 atagaggaag tgaaaatatg tacaatatat tagtagtaga cgatgataaa gaaattgttg
     4801 attcaataga aatatatctt aaatcagaag gatttaaaat atataaagca tatgatggaa
     4861 tgaaagcttt ggaaataata acagagaatg acattcatct aatactaatg gatataatga
     4921 tgcctaaatt agatggaatc aaagcaactg taaaaatacg agaagaaaga aatattccaa
     4981 taattttaat ttcagcaaaa agtgaagata cagataaaat aataggatta aatattggag
     5041 ctgatgatta tataacaaag ccatttaatc tattagagct tatagctagg gttaaatcaa
     5101 acttaagacg atatgtaact ttaggtaatt atgaagatac atgtaaagaa attttaaaaa
     5161 gtggagcttt ggagttaaat acactaacaa aagaagttaa aattgatggt gaaaacataa
     5221 aaatgacccc aattgagtat aaaataattg aacttctttt agaaaataaa ggacgagttt
     5281 tctcaataga tgagatatac gaaaaagtat ggaatgagga aagttttaat tcagaaaata
     5341 cagtagcagt acatatcaga cgaataagag aaaagattga aataaatcca aaagaaccaa
     5401 gatttttaaa ggtggtgtgg ggagttggtt ataagattga aaaattttag tggaaaaatt
     5461 ataaaagaaa agagtttaat atttaattgc attttgattt tagtcatttt tacatttaca
     5521 caaatgttag gaattttaat atgttttaat tttttctctg agagtttaat ttactctatg
     5581 gggattatgc ttttcttaaa ctttatttta tataaaatac tgacaatgta gatgaggtgg
     5641 gcaacttgga aaaatataga gcattaaaat tagtttcatt aatcataata tctatctcat
     5701 ttccattaac tatattgttg gctacaatag gacttgctga gcctaaatac aatatacaaa
     5761 aaacttctac aaagagtggg atttttaata tatctaatga tttttatgat agtaatatat
     5821 ttgatgaagg aacagtggaa agcttattat ctaattttaa gatatctgtg gatagtcagt
     5881 taactagtga agaaaaaagt aaactccaaa caaaaagtaa aagtatagat ttaagtagta
     5941 atgattctga gtatgataaa atcatgatta ataaacaagc ttctgaagaa tatttaagtt
     6001 atctaaaaaa tataaaagtg tatgttatta atacatatac aggagtattt tatacaaata
     6061 catcatatgg taatttagat gattttaaac aaaaaactaa gagctattgt aatatagaga
     6121 taataaataa tgtaggaaag agctcgtata ttaaaacaat aaatggagaa aaatttgaac
     6181 tgaataatct gagtatggaa ctaaatggag tagatgaagc ctttgaggca tatgtctctt
     6241 ttccagaaga gccaactata gaagatggaa tagtatacac taattttcaa atatttaaac
     6301 aagctacaga aaaagtaaga ttattttttg tagcttgttt aagtttagca attgtgtgtt
     6361 tattatctat cattttatat agcagaataa aaggtgaagt tttaaaaaga aataatgtat
     6421 ttttactaat atacagtaag atacctatgg aatttaatgt aatactagta tttatttcaa
     6481 ttgcaatttt aactatgtat gctcttgctg tatcttatca tattgatgta attgtattag
     6541 tttctttatc tttactgata gtatcaaata atatattttt tataaatgtg caattgagtt
     6601 atttagaaaa taaaatgtgt atatttaaga caagtattat agtaagagtg attttatggt
     6661 taataaaaac tgtaagggag gtcagtaacg ctataaagaa agtatcttta gcaaggaaag
     6721 ttattgttat agtgataata tctttagctt taatcatggt aattagcact cgaagtatag
     6781 gtatgggatt actgttttct atatgtattt ttttaggatt tacaatatat ataactaaaa
     6841 gactttcata tcttagttac gtaatagaag gtacagaaag aataaaaaag ggagaattag
     6901 attataagat aaaaattact gggaatgata attttacgtc tttagctgaa aatataaata
     6961 atattggaga aggtcttgat agagctatag aagagcaagt aaaaagtgaa agaatgaagt
     7021 ctgatcttat aacaaatgta tctcatgatt tgaaaactcc acttacttct ataataaatt
     7081 atgtagattt aattaaaaaa gaagaatcaa tacaaccaga gtatataaat gattatataa
     7141 aggtacttga gtcaaagtca aaaagactaa aattattgat agaagattta tttgaagcga
     7201 gtagagtaag tagtggcaat atagaattac aaattagcaa gattgattta gtgcaactat
     7261 taagacaaag cataggtgaa cttgaagaaa aattatctaa aaataattta tatttaaaat
     7321 taaatgttcc aaatgataag gtgtatatat gggcagatgg aagaagaatg tatagagtat
     7381 ttgaaaatct tttatctaat atagcaaaat attccttaga agaaactaga gtctatattg
     7441 atgtatatga ctatggtgaa aatgtaaagg taactatgaa aaatatatct tcttatgaat
     7501 taaattttga cccaagtgag attatggaaa gatttaaaag agctgatgaa tcaaggaata
     7561 ctgaaggaag tggattaggg cttgctattg caagagattt agtagcttta caaggtggaa
     7621 aattttatat agaaatagat ggagatttat ttaaagcaaa tttagagttt caaaaatatg
     7681 aagaagaaat aacaaatatg gaatgagata gtatttaagt atatatattt tttttactgt
     7741 cgaaagcttt tattataata tattagaata tttacagtag agaatgaaga gtaaaaacag
     7801 agtaacttta agtcactctg ttttttattt aaaatcaata atataacaac ttaaattaaa
     7861 attgtacaca tagttttaaa ataacttata caataaaaca ttatccaaat atcacaagat
     7921 aattccaaat aaatatatag atatcactcc tgtaataata gaaataccaa tagatttaaa
     7981 cttatatgca acaagaagta caatcataaa agatataatt ttagggttag ctatagataa
     8041 atatagacta tctccattaa aaaatacatc tttagcagtt aaggaagtaa gtattgctac
     8101 aggtataaat ttcatgattt ttttcaaaaa atcaggcatc tctttttttg aaaaaattaa
     8161 cataggaagc actcttggta gatatgtaac aatgtacatt ccaattataa taaaaaatat
     8221 ataattatta ttcataagat tcctcctttt tacagtaaga ttcttctata aagaaaccaa
     8281 ttaaagatgc taaaattgat gcaactatta ttactaaatt gcttttgaat aatgcatata
     8341 aaataacaga aataatgatt gatgatataa atactacaat ataaatctta ttttttattt
     8401 gagaaactat taaagctata aacatagaag tcaatatgaa gccagaaata gaactgtcta
     8461 tagatatact ttctcctaaa aatgctccaa taaaattagc taaaactgat gaaattaagc
     8521 agaagaaatt aagataaata gcatttctat cagaccaatt tccagcagta aatttttcat
     8581 aattaactgc aaaagtttca tctgttatag tatgacaaaa tggcaatata aattttggac
     8641 ttttattttt tatgtacatg ttcaaattag aactcattag aaaatgtctt aagttaacta
     8701 taaatgtagt caaaacaata gatgttacac ttgcaccagt agaaatcatt gaagctgcaa
     8761 tgaattgaga acttcctcca aatactaaag ttaccattag tgctatttga aaaggtgaaa
     8821 gaccagattt ttgtaatagt attcctccta ctatacctat aggtatataa cctaagaata
     8881 taggaattga agcaataaag ctttctttta attgttgagt tctttccaca ataaatcact
     8941 ccttttgtat taaatgtatt aaagtattag taaaacagaa aaatagatta attgtataat
     9001 tgcaattata attaaaaata aatttggatt aatatataaa atactataca acaaataaat
     9061 aatcttaaac ggttattaaa ttttatctat ttgttattat gatgtaataa tacatattaa
     9121 tctctataag ttaattacta tctggtgtaa ttttatttta acaacaaaaa aaaatacaca
     9181 caattaaaat attgtgtgca atacaattat tttttctctt ctaatagtct ttttaatacg
     9241 ctcagaccag ctttaagttc ttctgtgctt tctgtagcac atacagctat tcttattgca
     9301 gaaattggtt tttcttttcc aacagcaaaa cgttcagaag catagacctg tacaccttct
     9361 ttaagtgctt gtatctcaaa tttttctgcc attattccat caggtagaat caaccatcta
     9421 aatatacatt cttcatttcc caaaagatta tatccagata aatattgatt aataatcttg
     9481 tttcttcttc ttgcagattt acggcgtgca ttaattaatt tatcggcttc acctgatgta
     9541 atcatgcgat aagcaatttc tgttaaaaaa taagattgag atagattaat gttgtataat
     9601 gcgcttgata atgcctctcg atactgttta ggtgtagaga tatatgctag ccgtaaacta
     9661 ggtgcaataa tttttgataa actcgtaata taaattgttt gattgggcag ataggaagcc
     9721 actggattta aatgtgtttc attaagtaaa ctatgaatag catcctcaat aacaattaaa
     9781 ttgtatttag atgcaatatt tgcaatcatt tttcgtccat tttgtgacat tatatgtgta
     9841 gttggatttt gataatctgg tattatgtat agacctttaa tattttcatt tttacaagca
     9901 tataatagtc cttcttcact aatctcatta tcttcttgtt taattggaat tagttgaatc
     9961 ccaagcattt tagctgctgt ctttattcca ggataagtta atgggtctac acctattcta
    10021 tctccatgtt gaaacaaacc agctaaaata gcaacaattg cattttgtcc accacttgca
    10081 ggaagtaagc tatctgatgt agtttcaagc ccagctttat aaattaattt ggcaatagct
    10141 tctttttgcc atttagcacc atctctttgt ccatattgga atatagtttt aaaatctatt
    10201 tccttaatta tatgtttaaa caaagtattc atttcttcta gtgtgaaatc tggattcatt
    10261 gtgcccattt caataaatgt aattttatta ttactggaca tcaagaatag atttgaacgc
    10321 gtatcataag atacaaaagt tccacttcct gtaactccac ttattagacc ttttttttca
    10381 caaattttaa aagctctaga gatagtactc acattaacat ctaagaaatc tgccaattca
    10441 cgttggggtg gtaatttagt acctggtaat aaaaatccat tgttgatatc ttgttctagt
    10501 tgttctgcaa gcgccttata taatatttgc ccttttgaag gtctctttgg tttccagttc
    10561 ataggataat tttcaaaaga attaattggc ataagttttc acctcacatt attaatttga
    10621 ttttttcttt atctaaaaca ataaattcta aagatacaaa taaaaactga taggaaataa
    10681 ttctatcagt ttttgtcttt taattgattt caaatcttcc tataattttt ataccttctt
    10741 tatcataaag agggattgtt tttttaaata tattaaaatt tctttttctt gtatataaaa
    10801 cagcttcttc tggtgtcttt ggttgattat cacaatcgta caaatctctt ttttttacgt
    10861 agccgacttt tttacctcta cctattgttt gtataagttc tggttcaatg gaatttccat
    10921 ttgagtctat tatatgtgta ccataggttt ctccattttt attataatta atcttagcaa
    10981 tagtatattc tacatcttca ttttgtttaa aattggagtt gatagaaaat attgacccta
    11041 ttattataaa ggttaataaa aacttaagac ctaaattaat tttcttttta tcttgattaa
    11101 acatagaatt taacctcttt tttaaaataa tatttttttt atttagaaac tgagatacga
    11161 atgatgaata cttcaaagtt ttttgatact ttattgtatt taatattata tatgcatact
    11221 ctttaatttc actcgtggta catttgtcaa tcacaatttc atcacaagat aattcacata
    11281 attcatgaaa atattttttt aataagtata aaattggatt gaaccaatgt atgatacata
    11341 ttatactaat tagaagctta aataagttat cttttctttt ataatgaatt aattcatgtt
    11401 taaagataaa tcttaactct ttattattgt actttttttc tggaattatt attttacagc
    11461 gtgttaaacc tataatggca ggggaataaa tacctttaac cttatatatc tgaagttttt
    11521 tatttatact tagttctttt gcttgttcat ctaagatact agtaatatct atttctaaaa
    11581 tttctttttt aaaattttct atgtaattat aaaatttaaa atttgttctt aaatagtaaa
    11641 aagagattgc tataattcct aatatccaga tgtacataaa tatatctaaa gtaatgccct
    11701 ggtcatatgg tatataatta tcgagattat gtttatagat attaatagta gtattattga
    11761 tatttaatat atttaaattt attttagata taaacatcat tctgactact attaaaagac
    11821 atataaaata attaaactta aaagtatatt tgcttatctt tttagtaaat aaaatgaaaa
    11881 aaagaattag tagacttatg taaatattaa atttaataac ttctataaat aattccataa
    11941 aatacgtctc ctattttctt ttttttagcc attgttcaag ttcttttatg tcatcatctg
    12001 atatttcatt tccacaacct aatgatgata taaagctatg aatagaattt ttatgtataa
    12061 gctctaaaaa atcctttgtt tcaaatttta gatattcctc atgtttaact ttaatagtgt
    12121 ataaagtatt tctaccatct ttttcaaatt ctaaaaaacc tttatcactt aatctagaaa
    12181 gtactttacc agtagtacct tttgtccatc catgagaaat ttccatataa ttagctactt
    12241 ctctggctgg tattttatct atgcctttat cccatatgaa attcataact aacaactcgg
    12301 attttggtat ttttttcaat ataatcactc acctttaact tgattatatt agacaaatgt
    12361 ctaatagtca atataatata tcatcatgta taaagaatct ttatattatt ttatgcttga
    12421 gaactaagta gtatagattt atagataaaa aagatattga gagttttatg gaagagggga
    12481 atatattttc tattagagat aagaatatga catatatttt ttattgattt gtacaaaaat
    12541 actatatagt gaataaatta atatcttttc taaattagaa gaggataatc ttattagata
    12601 aagattatcc tctttattga aagtttaagg gatattagag attattaatt tttctctctt
    12661 tttttaacta aaagcaataa tacataaaat tattattgct aatgatactc ttaatgtggt
    12721 atatagtcat agtgtcacat gtttatcaat agttttttca ttaattattg taacgaatag
    12781 taggactcat aaaatactta gaaatatgtt tttagataga ttttaaatat ataatctaac
    12841 ttatatctat aaattaacac tattattctc caattccatt tctagttttt ttataaattt
    12901 attaaattct tctggttgcc tttttccaaa caatactctt acaagagctg aattgatttt
    12961 tccaaatata ttcctcttgc tctcactttc aataaaaata agttttgtat tttctaagtc
    13021 aatatgtact aattcatatc tagtaatagt actttctctt ttattgcttg tttttatctc
    13081 atatactcta tttttttcga aattagttat ttcaacctta aatcttttat tatttttttg
    13141 ttgtacaaat gttcctactg cttttttctc attaaaatta ggaaaattta gtcttgcaga
    13201 ttttgtaaat atattaaata tgtcttttgc agaatatttt aataaaactt cagttttaaa
    13261 tgtattcata tcgttttccc ttctgtatat aaatttaata tttataagtt aatttttaag
    13321 ttaaaatagt ataatatgcc atattaaatc atgttaaaac tatttatata gctaaaacct
    13381 tacctatata agtatgtata ctatcatata aaaataaaat cttaaaatag aaagggttaa
    13441 aaacacagtt tattataatt tttattgttg agtagatacg tactattata tatgattgag
    13501 caagtttttc aatcataaat ttataaagta ttttgcatta aaatttaaac aaagagttaa
    13561 attatttaag attatgaata actaatacat ttagtaaatt actaaatata caaaatgtaa
    13621 atacttatca aaatgtataa atacttatga catctagtta cttacagggt ttaagtagaa
    13681 aaaaatatca aagtaagtat ggcatgatag ttgcttatat atttatcaag aaaggagtta
    13741 ttaagcatgg agttgagaga taaacttgta aacatcataa atacagaaaa taaaaaagat
    13801 ccattaacag atgttcaaat agcaaagttt ttaagtacaa ctagagagaa cataactaat
    13861 ttgagaaaag aacttaatat aagtaattca aggcaaagaa gatatcctta tttaaaatca
    13921 gcaatttcgg caatattaca aaagaataag aatatttcta tatcagaaat tacaagggaa
    13981 ttgatgacag aaggctttaa tatatcgaga agagttgtgg aggaactttt acctaaagaa
    14041 agtttagaaa tggatgtagt agaggaatct gaagaagaat cgaatgaccc atttgaaact
    14101 ctgataggta ataaagggag tcttagaaat gctgtggagc aggctaaatc tgctatattg
    14161 tatccaccaa aaggattacc aacgttgatt attggggaaa gtggagttgg taagagttta
    14221 ttttctagac atatgtatga gtttgcaaag caaaaaaaga tagtaaaaga aagctccaat
    14281 tttgttgtat ttaactgtgc tgattatagt gacaatccac aattattatt atctttgtta
    14341 tttggatata aaaaaggtgc atttacaggt gctgaatatg atacaccagg tcttgtagaa
    14401 gaagctgatg aaggagtttt atttttggat gaaatacata gattgcctcc aaaaggtcaa
    14461 gaaatactat tttctatctt agatagggga aagtttagga gattaggtga aactaatgct
    14521 gaaagaaaag taagtattat gttgattggg gcaactactg aaaatgtaga gactaattta
    14581 ttattaacat tcagaagaag gataccaatg ctaataactt tgccaccatt acatgataga
    14641 ttactaaaag agaaaataga ccttatatac aatatctttc aacaagagtg taatagaata
    14701 aatgcaaaaa tatttgtaga taaaaatgtg attgaaatac ttgtactaaa aaagtttagt
    14761 ggaaatatag gacaattaca aaatatgatt caggttcttt gtgcaagagc ttttatgaag
    14821 tttataaatt ccaaagatga agatagtgaa tcgatagtag tagtagatat aaatgaagtt
    14881 ttaaagctta aagattcttt taaagatgct gcctttcaag agattgaata tacagagata
    14941 agaaaatatt tgaaaaatgc tatatttata ccatttaatt tagaagaatc atcagtaaaa
    15001 ggaagtcttt taagtgatga atatatatta ccagaggaca tatacaaaac aattgaaaag
    15061 aaatattatg acctaaaatc cctagacatt gaagatatag atatagagaa tattttatgg
    15121 acttttattt taaatagatt tgctgactta aagtttaatc tcgatagtaa tgaagaaatt
    15181 ttttcaatga gtgatttaaa tagttttgta agtgatagtt tagttaaact ggtaaaagaa
    15241 cttatgaatg atatagttga aaaaaatatg aatttagaag taaataaaaa tatgttcaaa
    15301 tatctagcaa tacacttaga agaagctata aaaagaatta agctaaatca aaagataata
    15361 aatgtaaatt tagaaaaaat aaagattgac ttttcaaaag aatatgaaat tagtaaaagt
    15421 tttgcaataa aaattgagga atcaattagt attaagattc cagatgatga aattggattt
    15481 ataacactct acataaagtc tgctctaaaa aatgaagtga aaaaagataa agtagggtta
    15541 ataataattt ctcatggacg tatagctaca gagactgtaa atgtagttaa agaactttta
    15601 ggtgtaaagt ttcctgtggc tatagatatg cctttagatg aaaaaccaat aaatatatac
    15661 aataaggcag tagaactgtc aaaaataata gaccaaggga aaggtatatt gtttttggtg
    15721 gatattggtt cacttacaaa cataggtcaa atagtaaata agagaaccaa tataagcact
    15781 aaaactattg atagagtaga cctcctaatg gcactagaag caactagaaa agtttctatg
    15841 ggagaggaag aacttgatga aatatttttt tctttgctaa aagataggat gggatataac
    15901 tatgaattag aaaaacacat agataaatca aatgcaattg taacattatg tcttactgga
    15961 gaaggaactg ctaagtatat aagtaaaacg ttggaagaaa agtatgataa cactaaatgt
    16021 tatcaaatga gtgcattgga tgaaaattta ttttgtaaaa ttgaaaatct aaaagagaca
    16081 aacaatatat tagctattgt tgggacaata aaccctaaga taccaggtat aaattttata
    16141 ccctataata aagaactttt caaaaatttg gatatctatc tatcaaaatc aaaacaacaa
    16201 gatgacagac cagttaaatc gtatgaaaga atgcttgatg aggatttagt gatttttgaa
    16261 ccagatatat attttaaaaa ggatttatta gaatatgtat gttcaattct tataaataaa
    16321 gaatatgtag aaaaagatta cttagattct gttttacata gagaagaaat gcttccaaca
    16381 tattctaaag gagctatagg tgtgcctcat ggagattctt ctactgtaaa tagtacaagg
    16441 tttgtttttg ttaaactaaa gaatcctatt gattggggtg taggtaatgt aaatttcata
    16501 tttatgccag tttttcaggc taatgataaa gagattgtta aaaatgttct tgagatacta
    16561 aaagatgcag aatttatgaa caatgccaat aagtgttttg ataaagatgc ttttagaagg
    16621 attatatttg ataaatttaa acatctgtag ccatagcaaa aaaattgaga ggagttagag
    16681 taatgaatgt agatttaata tcattgggtt tagaatctaa tgattatgaa agtgttattg
    16741 aagaattagg aagtataatg tgtaaaaaag aatatgtaaa agaaacatac ataaatgctg
    16801 tcttggaaag agaaaggaca ttaccaacag gtctagatat tggagaaatg tgtgttgcta
    16861 ttccacatac agattcaaag catgtaaatg agtctaatgt agctgtaggg atattgaaaa
    16921 atcctgtaaa gtttaattca atgatagacc caaaagatag acttgatgta gaacttgtat
    16981 ttttattagc agtaaagaac ccagattcac aagtaaaact gttaaaagat ttaatgtcag
    17041 tttttcaaaa tataaagtta ttaaaaaata taaaaaacgc atcaacaaaa gaagaagtag
    17101 ctaaattatt ggattttata gaaatttaat gtaggagaat tttataaata aaaaattaaa
    17161 atttcaacaa tcaaagtaag tattattttt ttaataggtt taatcttata taaaataaaa
    17221 atttagagtg aaaaattagg aggaaattat tatgaaacaa tttaatgtat tatcagtttg
    17281 tggttcaggg acagttacat catctatggt agcaggtaaa ttaaaagaag tactaggtaa
    17341 taaggggatt tctattacta caacagaagc tagaccaaca gaagcactaa atttagcaca
    17401 atcaggaaga tttgacttta taacatttac gagtccgctt caaacaggcg attatggaat
    17461 accaactata aatgcatttg cttgcctaac tggtataggg gaagaggcat tctttgaaga
    17521 agttttgact gttattgaag gcatagataa gtaagttttg gagacgtgaa tttatagtat
    17581 ttaaatcaat gatttagata ctataataag ctaatattaa ctaaatattt gtggaaaaaa
    17641 cattttatat gttgtcataa attaaaaaat tataaaaata gtcacttaag tattaaatta
    17701 agcttataaa tatttataag taggagggaa aaagatgtta gaatttatga aatctataat
    17761 cgatacattt ggttctgcaa ttatagttcc aattataata ttcataatag caaagatatt
    17821 taaagtaact actaagaaat cgtttctttc tgctgtgtat gcaggagttg ctttacaagg
    17881 ttttacactg attttaaatt catttacacc aataataaca ccagttatca ataggatggt
    17941 tgagagtaca ggagtaaacc taccagtttt tgatgttggt tggcaagcaa catcattggt
    18001 tgcattttca acaagtgcag gtatgatata tttaggtctt ggtatattat tacaaacaat
    18061 tttatttttg ataaaatgga cagacgtgtt tcaaccatca gatttatgga ataactattc
    18121 ttatatggta tggggagcaa tggttatagg agtaacagga aattttcctt taggtatagc
    18181 atgtatggtt ttattaaact tatatagttt attaatatca gagttagttg caaagagatg
    18241 gtctagttac tatagatatc ctaattgtac aataatagct atgcataatg ttgaggcttc
    18301 tgtgtttgca gtattttcag accctatata caataaattg ggattaaata aaataaaatt
    18361 aaatccaaaa gaattagaga agaaattagg gtttttaggt gaaccaatta ctttaggtct
    18421 ttttttaggt atgtttatag gtatattagg taatatgacg agaataaata ctatggaagc
    18481 ttggggagaa ataatgaaag taggtatatc tacaagtgca gtgatggcga ttttccctaa
    18541 agtagcaagt atgtttgctc aagcatttgc acctataaca gaagcagcta gaaagattat
    18601 gcaaaaagct ggaaaccgtg agtggtacat agcagtaaat gatgctgttg gatatggtga
    18661 acctgcaact ttaatatcag gtcttatatt aattccaata atgcttgtaa tatctatggt
    18721 acttcctggt aataaggtat taccagttgt ggatttgttg gcaattccat atatggttca
    18781 aggtttagtt gccatacata atggtaatat accaaaagta ttagtttcag gtataatttg
    18841 gtttggatta ggattatatg tttgtacatc tacagcacca ttatttacag atatggctac
    18901 aaatataggt gtagctatac ctgcaggagc aatgttaata acaagcttta atatactagg
    18961 aaaacctttg atgggattag ttttctttgc atttctaagt gcaaatccaa tttatatagg
    19021 tctttcagtt gtaatttact ttgttctatg ggcattgttt agaaagaaca aaacaagtat
    19081 tcttgattat ttagaaaaac aagcacttaa aaatgtagaa gaagagcctg tagcagttta
    19141 agtttataaa aatgaaataa gaataattaa aggagtttat aattgatttt atataagtat
    19201 cagataatac ctgagaaata tttaaatgaa atatagactt ctttttattt gataatattt
    19261 gtaattataa tgcattgtat ttttatagtt gagttttctg tataacctgc tatttaaaac
    19321 atactctttt atatttatac agtaatgtgg tttaatttta taaaatgtaa tctctactgg
    19381 taaaagactt tgtatataag gcatttgcct gaataaacca tttatctttt gtatggcata
    19441 gatattgcta tatagaagta tatagcatga aaggagatat ttatatggga gataaaatga
    19501 gagcatcagt attgtataat gtaggtgatg tcaggtatga aatggtagat ataccagaaa
    19561 taacagatac gcaagtgctt gtaaatgtaa aatatgttgg gatatgtggt tcagatttgc
    19621 ctaggtctat ggtaagtggt ttgagtggaa atacaaaata tccattgatt ttaggacatg
    19681 aattttctgg tgaagttgtt aaaattggag aaaaagtaaa gcatattaat gtaggagata
    19741 gagtagctgt tgcaccatta gtaccttgtg gaaaatgtga ttattgtaat gaaggtaatt
    19801 ttggcttgtg tgatgattac aatataattg gaacaagagt aaatggagcg tttgcagaat
    19861 atgtaagagt tccagaagaa catattttaa aactaccaga tacattggat tatgaaactg
    19921 ctgccggaat tgaaccagca actatagctt atcatgggat ttcaaagtct aatattagag
    19981 taggagatag tgtagttgtg ttaggatgtg gtccaatagg tcagtttgtt atacaatggg
    20041 caaaggtgtt tggtgcatct aagattatag cagttgatat ttttgatgaa aaattagaac
    20101 tttctaaact tctaggagca aactatatac ttaactcaaa agaagtaaat gtaatcaaag
    20161 aaataaaaaa aataacaaat ggtggtgctg atgttgtaat agagactgct ggtagccgat
    20221 ttacacaaga acaatctcta tttgtagcaa aaaagagagg aaatatagtg tttgtaggta
    20281 tatcacacac agaattacca cttagtgcag acgctactga gtgtatatta cgtggagaac
    20341 ttaccttgaa aggttcttgg aattcatatg caagccctta tcctggaaga gcatggactg
    20401 caacattgga ttttatggga aaaggtgaca ttatttttaa acccatgatt tcacataaaa
    20461 taggtcttaa tgaagtgggt gactttttaa gtaaaatgag caagagagaa attaatttca
    20521 ataaaatcct agtagaaata taaaaattta ataaaaaatt ctaaaaacaa ttaaatttta
    20581 taactatgac attaaataaa atataggagg aagaaaagtg ctagaaattt taaaagaaga
    20641 agtattaaaa gcaaacttag aattacctaa gaaaaagcta attacttata cttggggaaa
    20701 tgtaagtggg atagatagag aaaaaggatt agtggtgata aaaccaagtg gtgtagagta
    20761 tagtaatatg actgtagaag atatggttgt agttgattta gagggaaatg tagttgatgg
    20821 caaactaaga ccctcctcag atactccgac tcatctagtt ttatataaag agtttgaaga
    20881 attgggggga atagtacata cacattcaag ttgggcaaca atttgggctc aaataggaaa
    20941 atctatacca tcttgtggta ctactcatgc agattatttt tatggaagca taccatgtac
    21001 cagaaaaatg actagagaag aaatttgcaa tgaatacgaa aaggaaactg gaaatgtaat
    21061 cattgaagaa tttatgggaa gaaatccaat tcattgtcca ggaataattg taaatgacca
    21121 cggacctttt acatggggaa aagatgcaaa tgaggctgta cacaatgcag tagttttaga
    21181 agaagtcgca aagatggctt attatacaga gttaatgagt cctgataata ttatggataa
    21241 ggttcttatg aataagcatt tttcaagaaa acatggaaaa aatgcatact atggtcaaaa
    21301 atgattatct ggaggtgaat tatgctagac tctttaaaag gtaaagttgt ggaaatagca
    21361 attaaagcag agcattatgg tttatgtaaa gaaaagactg gtaattttag tattagagat
    21421 aaggatactg gatatatact tataacccca tcaggtatag gaagagaaga attaaacgtt
    21481 gaacatattt gtgtattgga tttgaatgga aatgtaatag aagttgagaa aggtattaag
    21541 ccaagtagtg aggtattgat gcatattgaa atatataaaa taagggaaaa tataaatgct
    21601 atatcacata ctcattcttt atatgcaaca gcattttcag tagcaaagaa accaattata
    21661 ccaattgtat atgaatcagt taattatggc ggttatgtag atattgctcc atacgaaaga
    21721 ccaggaactt taaaattagc taagagcgtt tcaaaattac tgatagatac agatgcatgc
    21781 ttattagaaa gacatgggtt gacaactgta ggtaatgatt tagacgaagc attattaaaa
    21841 tcaagatatg ttgaagaggt agcagaaata tactataggt ctttagtatt aaatcaattt
    21901 aaagaacttg aagtagtaga tgttgatgag tttgaatctt ggaaataccc agaagaaata
    21961 aagttttaat ctaaataatt ttcattgaag tggttaatta aaatatatgt attatttata
    22021 tcaattacta tgttttatta tattaatcac cgtattttgt aaatatattt attacatttt
    22081 ttcaaaaaaa tatagaatcc gaaagccata taaaattgac ttgggattct atacttttta
    22141 tttatgcatt tttctttatc tgattttctg gagaatttat atgttcaaaa tattttttag
    22201 tttcagatac tattataggt gataatgcaa gtaaagctat aaggttaggt attgccataa
    22261 gcccatttac aatatcagca attatccaaa caacttctaa ctttaagaaa gcacctaata
    22321 acaccatagc cacaaataca gttctatacc cattcatgcc ttttacacca aacagaaatt
    22381 caaaacatct ttctccataa taactccatc ccaaaattgt agtaaatgca aataatgtta
    22441 aactaactgt aagtaatatt ggtccaaatg taggaattgc tccgttaaaa gctgcttgtg
    22501 tcataacagc tccatttagg tctgaacacc acactcctga aataacaaga gagaatccag
    22561 taagagtaca gattataata gtatctataa aagtacctgt catagatata agaccttgtt
    22621 ccgctggcca ttcagtttta gcagcagctg cagctattgg agcactacct agaccagact
    22681 catttgaaaa tacaccacga gcaataccat ttctaattgc cagtgacata gttgctccta
    22741 aaaaaccacc agtagcagca gtaggtgtaa atgcactttt aattattaac ataaaagttt
    22801 cagggatttt attccaaaaa gatattaaaa tgattccaca gattacaaca tatataactg
    22861 ccataaaagg tactatttta gtagctacat tagatatact tctaagtcct ccaaatacaa
    22921 ccaaagctac aaatactgct aatacaaccc ctgtaattct agggtctatc ccgaaactat
    22981 tatttattgc atctgttatt gaatttactt gagtaaaagt accgattcct aaaagtgcaa
    23041 ctagtatacc acttatagcg aaaaatattg caagaggtct ccatttttct cccataccat
    23101 ttactatgta atacattggc ccaccagaca cttgaccatt tttatcttta gttctgtatt
    23161 ttattgcaag aacaccttct gaatacttag tagccattcc aaagaatgct gctatccaca
    23221 tccaaaaaag tgcaccaggt ccaccagctt tgatagctgt agcaacacca acaatattac
    23281 cagtaccaac tgtagcagct agagcagtac ataaggctgc aaaacttgaa acatcaccac
    23341 tacctttgtt ttcagcagag aatattaact taagagctct tggcagttta gttatttgaa
    23401 caactccaag cttaacagta agtagtatac cagtaccaac taatagtacc agtaggggtg
    23461 gtccccaaat aaaagcatca actttgttta aaatatcaat tagattcata aaaacactcc
    23521 ctcatttttt ttgctttaca taatcaatag aatttttaat gaagtaattg acaggaaata
    23581 agtataattt attaataatt tctagtgtaa taaaaaaagc taaatctaaa aaagattcag
    23641 ctctggatgt acactaatta gcaaccaaaa taaaagtatt agtaaatact gtttttggta
    23701 gataatccct gtccttttgc ctgagagatt gagcataaaa gccttgcccc ttcggcgccc
    23761 ataatgggtc tctccagagt tccgtaaatt ttacagtcct acttttaaaa gtacctgaga
    23821 gtgttactcc ttcggtgtgc tatatagcaa ctcttctata aaatcttaac cggatattga
    23881 tttgtcatag cttattgtat taataatatt aatataagtt tttatgtttt gtcaactaaa
    23941 aaattaaaaa acaaagaaaa aatataaaaa tgtaagccta tttacgaatt ataaacttag
    24001 aaagatgagt aatatacgta aaaatgaatt ttgtaataca catacaaatg aagtgtaaaa
    24061 taagttttaa ataaaaaaat aataaaatct taaataatta attagatatg attaaattat
    24121 ggtaatatta tagttacgat attaagaaaa gttctattta gttagatttt aagcgtaata
    24181 tgagattatg tatagagaaa ggatgtattt ttagatggga aaaatattag tgctagcaga
    24241 aaaaccttct gttggaagag atatagcaaa agttttaggg tcaaaaaatg aaaaaaatgg
    24301 ttatatagag gggccaaagt atgtgataac ttgggcacta ggtcatttgg ttacacttgc
    24361 tgaccccgaa agttatggag aaagatataa atcatggagc ttagaagacc tgccaatact
    24421 tcccaagcac cttaagactg ttgtaataaa aaagagtgga aagcagttta atacagttaa
    24481 atcgcaaatg aatagaaatg atatagatga aatagttata gcaacagatg caggtcgtga
    24541 aggagaactt gtagcaaggt ggataataga aaaatcacag gtaaaaaaac ctataaaacg
    24601 tctttggatt tcttcaagta cagacaaagc aataaaagac ggatttgcaa aattaagaag
    24661 tggaaaagaa tatgaaaatt tgtattactc agcaatagca cgagcagaag ctgattggat
    24721 tattggaata aatgcaacca gagctttgac aacaaagtac aatgcacagc tttcttgtgg
    24781 aagagtacaa actcctactc ttgcaatgtt gcttaaaaga gaagaagaaa taagaaattt
    24841 caaacctaaa gagtattatg gattagaatt aattgctaca aagggaaatt cagatataaa
    24901 atttatttgg aatgataaaa acaataattc ttcaactttt agtaaagaaa agatagaatc
    24961 catattaaaa aaagtaaaag gtgtagacat aaaaatatct gaagtaaaca agtcatataa
    25021 gaaaaaatat tcacctgcac tctatgattt aacagaatta caaagagatg caaataaaat
    25081 gtttggattt tcagcaaaag aaactttatc tataatgcaa aaactgtatg aacatcataa
    25141 agtacttact tatcctagaa ctgattctag atatttaaca tcagatattg ttggaacatt
    25201 aaaagataga ataaaagctg taaatattag tgattattca aagatttgta ataaattatt
    25261 aaaaagcaat attatagcta ataaatcgtt tgttgacaat tcaaaggtaa cagaccacca
    25321 tgcaataata ccaacagaac agaaggtatt catgagtgat tttagtgaca aagagcgaaa
    25381 aatatataat cttgtagtaa aaagattttt agcagtacta tctcctcctt ttgaatatga
    25441 gcagacaact ataagtgcaa ctgtagaagg agaaatattt aaggctaagg gaaacaaagt
    25501 aataaattta ggttggaaag aaagttataa agatattgaa gatgaagatg agtatgaaag
    25561 tataccaaat gttttagaaa aagatgtact taaggtcaag ggattaaaga taacttcagg
    25621 aaaaacaaat ccaccaccat acttaaatga gggaacatta ttgactgcta tggaaaagaa
    25681 tggtctaggg acagttgcta caagagcaga tataatagaa aaattattca attcattttt
    25741 aatggaaaag aaaaataaag agatatatat aacatcaaaa ggaagacaat tattagattt
    25801 agttccagta gacttaaaga caccagaact tacagcttca tgggaaaaga aattattgga
    25861 tatttcaaag ggaaaactta gtaaaaatac attcataaat gacatgaaag attattcaaa
    25921 agatattgta ctagaagtaa aaaatagtga taataaattt aaacatgata acttaactaa
    25981 aaatagatgt ccagaatgtg gtaaatttat gttagaggta aatggtaaaa aaggtaagat
    26041 gttgatttgt gaagatagag agtgtaatac tagaaaaact atatcacaag taaccaattc
    26101 aagatgtcct aactgtcata aaaaattaga acttcgtgga gaaggtgagg ggagaatctt
    26161 cacttgtagt tgcggataca gagaaaagtt gtcttctttc aacaagagaa agcaagaaga
    26221 aaaacagaag gcatcaaaaa aagatgttaa tcaatattta aaaaatcaaa ataaaaatca
    26281 agagacattt aataatccat ttgcagaagc attagctaag ctaaaaaaca aataatttta
    26341 aagttattat tatacacaat tataacttta actgtatatt agttatatgt actgatataa
    26401 tatagtgtat agtttaggca tgaaagtagg gctgttaaat ggatttaagt ggcatattta
    26461 aatactattg taaagagtgt gaaaatacat ggaataattc gagtgttgaa ttatttgagg
    26521 atatagaaac gtatagtaaa gattcacaaa aaaagaggga aaaagaatta gataaattta
    26581 taaatacaat atcagttcat ttagagaggt atccaagtga tgctgtattg agaaaaatgt
    26641 gggtaaaaaa gggcgaggtt ttcttacaaa agacattgga aaaagaaaat atttttaagt
    26701 tagaaaaaat ggatgtagag gatagaaaaa aatttttaga tataacaaaa cagtttatta
    26761 gagatgctag aaaatttgat gatgatttac ctataggtga tattatgcaa gctatgagga
    26821 atgtatggat ttcaaatgca ttacaattat tatttggtaa agaaatatat tattcaaaag
    26881 ctaactttgc atatagtatg ttatatccat atactgataa ttatttagac aatacaaata
    26941 tagataaaaa tgataagatt ttatttaata actggttaga aaaaaggctc ctgggagaac
    27001 atattaaatc taaggattat catgaaagta aagtatctca aatgatagat tatattgaaa
    27061 gtgtataccc tagagaaaag tttacacaag tttatgaatc gttattatta atatttaaaa
    27121 gtcaagtaaa tagtttaaaa caacatggta aggaaaatca tttgtgtaaa gaagatttat
    27181 tatccatttc tattgaaaaa ggaggttcat ccgttttagt agatggatat ttaataagtg
    27241 gatttatgac aaaggaagaa atagagtttt gtataggata tggattttta ttacaaatat
    27301 ctgatgattt acaagatata aaagaagatt taaaatacaa ccataaaact attattacag
    27361 agatgtcaaa agagggtact ttagataaag ttgtaaataa actaataaat tttactattg
    27421 agttaataga tagttttaaa attaataata aaaataaatc tgtaataact atgataaaga
    27481 atgattgctt aatgttaatt ttattttctg tagtttataa tgctgaattt ttttctgtag
    27541 gatatataaa agaagtagag aaatttattc catatacaat agattattca ttagagattg
    27601 aagaaaaaat aaaagaaaaa tttaaaaata tagatgtttt aaataatgaa aatgaatata
    27661 aagaaatgat tgatattatt tgtgcagagt agaaaaaaag ggagtgtctt agaatagact
    27721 ttttagttta tgaggcactc tttttgtata aaatcaaatg tattttcatc attttaacaa
    27781 ttaaaaagag cttatccctg tttgagaaag ccctttttaa tttaaataaa aatgtcaagg
    27841 ttaaactatt taaatgcagt aataatccca ttatcatgta agttttttat gattgtagct
    27901 gcgataggga atccaaataa tccagctatt ccaaatagtt gagctccaat aaacatacac
    27961 attaatgtta ttaaaggata taggccaatt tggtgtccta ctacctttgg ttctaatatt
    28021 tgtctaacaa cggttataat tatgtatagt attaaaagtc ctattgctaa attaatattt
    28081 ccattaatga gtgagataat catccaaggt gtcaaaatac ttcctgtacc caagactggc
    28141 aaaatatcaa caagtgctat gatgacagat atagtaaatg cattttcaac ctttaggata
    28201 gtaagtccaa taagtagttc taagaatgtc actgatagta gtattgcata ggcttttagt
    28261 agttttaaaa gagcattaat actgctattt tttatattta ttatcataaa ttgacttttt
    28321 tctggaaatt gttttaagat aaagtttact attttttgat agtcaaaagt aaagaaaaaa
    28381 gaagcaatta aagtaataat aagttttaac ataaatgcag gtgttttact tgcaatacta
    28441 gcaatagcat tgagtgcatt tgttgaaata gaagctacta aagacatcat agattgactt
    28501 atattatccc aaccaagtat taatgatagg ttaacattag gtgtactagc atctatcttt
    28561 gaaaataaag tatttagcgt tggttgtata cttgatttat atatttcagg aagtctaaaa
    28621 aatacatcac ttacacttgc aaatatcttc acaccaaagc taactaataa aaatatacac
    28681 aacccataaa aaattaaaag tattactata gaaataagtg tacgatttaa atttgtatta
    28741 tttgtaataa gtcttataat aggtcttaag atggatgcaa tgataaaact gattacaaaa
    28801 ggcattaata atggcaataa gaattttaat acaatatata caatacttgt tattaaaact
    28861 acatatgtaa atttaattat aaaattcttt tgcttttgaa tatccataat ataaaacctc
    28921 caatgtattt gatattattc taaatatggt cttttttaca gaaaatatac tactgtatat
    28981 tgattataaa ctataaagct tatgtaaagt aaataaatta tgtaaaattt aggttaattt
    29041 tgtataaaga gatactttta tattttacaa ttaataacca aatactaaaa aatattttaa
    29101 ataaagaact taaaattgtg ataaaattaa tttatagata ttaaaaaaag tataatatat
    29161 ggtttttaag aggtgctaag atgaaaaatt ttagagattt aggtgggaac aaaactgagg
    29221 atggcagaac tgtaaagaag ggattatttt ataggtctgc aaaattatca aatctaagtg
    29281 aaaatgatat aaagatttta aaagagttaa atattaaata tatatttgat tatagaagtg
    29341 atgaagaagc tcgtaaacat ccatcaacaa taatatcaaa tataaaaaat ataagaatac
    29401 cagcaatgag agagctagaa gaatcaggag gaagttttgg ttctattgaa gatatgattg
    29461 atggattgtt tgaaaaagat ggtgcattta atatgttaaa taatagttac tataatttgc
    29521 ctataaataa tccgtcatat aaaaaattag tagaacttat aagagactat tctaatttac
    29581 caatattaaa tcattgtaca gctggtaagg atagaactgg tgtggggagt gctataattc
    29641 ttatgatttt aggggtatcg agagagaata taatgaaaga ttatctaaaa agtaatgatt
    29701 ttgcagataa agagatagaa agatttatag aatataagcc taaatttaag gacattccaa
    29761 aagaaaattt aaaatatata tttggtgtaa atgaagagta tatgaaaact gcatttagaa
    29821 gaattgatga agaatacatt agtgtagaag catatttata tggagaattt aatttaaata
    29881 aagaagaaat aagaaaatta agaaatcaat atctagagta aaaggtgagt ttatgagttt
    29941 aaatataaca gcaagacaga taaatataat aaaaatattg ttaaattcaa aagatacaat
    30001 tagtggtatt gccttaagtc aagagatagg atgttcttca aaaactatac aaaatgaaat
    30061 aaaggatatt aataaacaac ttagaaatgg taaaattttg tcaataagag gagttggtta
    30121 taaactagaa ggaagttttg atgaggtaaa tctaaatagc aatctctatg atgatgtaga
    30181 tagagtagaa tatataatca gaaaaatatt aaccttaagt aatgaagaaa aaaatactat
    30241 aaaacttgaa gatttagccg attctatgta tgtaagtgtt tcaacagtaa aaaatgattt
    30301 aaaagaagta aaaagaatat tggaaaagta ttcaatatca gttaaatcta agcataaaca
    30361 aggtatatgt gttttggaaa gtgaagataa gatattaaat tgtatagttg acttaagcaa
    30421 taagagagat aatcaattga gtttaaatga ttttttaaat gacgatataa aggaaagaaa
    30481 actattaata aaaaaattat tattagacat attaaatgaa aatggattag tattaactga
    30541 tatagaattt aagagtgtgt taaataatat attagttatg ttaagcagac ataagtataa
    30601 tgaaaaagaa tttatagaga attatataga aaattatagg agcaaaagaa gctcaatttt
    30661 agaaaatgaa caaaacaaag aaattataat aaattcaata aaaacatttt gtaaaaattt
    30721 aaaattagct acatcaatag atataagtaa tgataaggta tttgaagagt ttttatataa
    30781 gcatattagt agtttatgta aaaaaataaa gttaggtata aatcaatcac ctataatggc
    30841 tcaagatata aaaataaaat atccatttgc ttttgaacta gctaatatag ctaaaaagac
    30901 aatagaaaaa gatttgaaga tagaaattaa tgaagatgaa gttgcaaaca tagctctaca
    30961 tataggagga gcagttgaaa gagcatctta taataataaa gataaggttt tcaaaactat
    31021 aatagtttgt acttcaggca taggcacatc aatgttaata aaagctaaat tagagaatat
    31081 atttaaggaa aaattagaaa tactaaagat tattccttca tacttagttg aatatataaa
    31141 agttatagat gttgattttg taatatctac tgttcctatt gaagtaggag atgtgccagt
    31201 aataaatata tctccaattt taagtgagaa agaaattaga ttaattgaaa aatatataga
    31261 aacaggaaat atatacctag atttagatat aaaaagcctg tttgatagtg aattattttt
    31321 tactgatttg gtgtttaaaa ggaaagaaga agttatagat tttatggcaa gtaaacttgt
    31381 acaaaagggc tatatagatg aggatatgaa aaaatcttac tttgagagag aaaaaatagc
    31441 aacaacagaa atagggaata tggtaactat accacatgga gctattggaa aaatttttga
    31501 taataaaata gcaattggta tattaaagaa gcctatttct tgggaaatat cagatgttcg
    31561 tttaataata atgttagccc ttgataaaga taaaatatta gattatgaag taatattttc
    31621 aaaaatatat aaaagagtag attctatagc aaaagttata agtatatgtg aaaatagtag
    31681 ttttgaaaaa tttgtaaatt tatttaatta gatgggtagt attgtatata cacctgtaaa
    31741 tttggataat ataaaactaa ataagataaa aacgataaat ttctctttta attaagagaa
    31801 attttttgac tttcaaggat attaatataa agttaagata taaacataaa gcaaataaat
    31861 aaaaaagagg tggcaatatg atttatacag tgacattaaa tccatcaata gattatatag
    31921 ttaagctaga tgagctaaag acaggaagta caaatcgtgt aaaagaagaa tacgtttatc
    31981 caggaggaaa aggtataaat gtatctcgca tacttaagga acttggaaat gataatacat
    32041 ctttaggttt tataagtggt tttactggag aatatataat aagaacattg gaagaaaaag
    32101 aattgaagac agattttata aagataaaaa gtggtttttc aagaataaat gtaaaaataa
    32161 aggcgttaaa ggaaactgag attaatggac aaggtccaaa tatagatgat gaagacattg
    32221 atactttata taaaaaactt gataagctaa atcaagatga tattttaata ttggcaggaa
    32281 gtataccatc tactttagat gaaaaactat acgaaaatat aatggctaga ttagaaaaaa
    32341 agaatataaa agttgtagta gatgcaacta aaaatcttct tcttaatgtt ttaaaataca
    32401 aaccttttct aattaagcct aataacgacg aattagaaga actatttggt gttaaattaa
    32461 attcaattga agacatggta aaatatgcta aaagattaaa ggaaatggga gctataaatg
    32521 tcttggtatc aatgggaaaa gatggagcat tgttgattac agaggaagat gaagtgctta
    32581 taagtgatgt ccctaaagga aaagtaaaaa attctgtagg agcaggtgat tcaatggtag
    32641 caggatttat atctgggtat ttgaatactg ggaaatatga ttatgctctt aaattgggag
    32701 cagcttcagg tagtgcaact gctttttcat atgacttagc caaaagagaa tacattgata
    32761 aattggtaaa tgagatatct gtaaagcagt tttaaaatat taaaaaatat atagaaaggt
    32821 aattaatatt tatgaaaatt atagatttat tagatgaaaa gtcaattaag ttaaatttaa
    32881 attcaaaaac caaatcagaa gcaatagaag aattagtaga tttggtcgca aatagtggaa
    32941 atttaaatga taaagaaaac tacaaaaaag caattttggc tcgtgaagaa atgagtacaa
    33001 caggaattgg agaaggtgta gctatacctc atgctaaaaa ttcttcagtt actaaagctt
    33061 gtatagcagc agcagtgtca aaagaaggta tagattatga atcgtttgac ggaagtttat
    33121 caaatctatt ttttatgata gctgcaccag acggagctaa caatactcat cttgaagtat
    33181 tatcaagatt atctacaata cttatggatg aagactttag aaataaactt ataaattcaa
    33241 gctctgaaaa agaatttaag gaaataatag ataaaaagga aagagaaaaa ttcagtgaag
    33301 aatatcaaga tgagaaagtg gctgaaaaaa atataataga tactaaagag aatgatgcta
    33361 ataagtatcc taaggtttta gcagtaacag catgtccaac tggaatagca catacattta
    33421 tggcagctga aagtttaaat aaaatggcag aaaacaaagg tgtatcaata aaagtagaaa
    33481 ctaatggttc agcaggtgtt aaaaataagc ttacaaaaga tgaaatagaa aatgcaacat
    33541 gtataatagt ggcagcagat aaaaatgttg agatggctag atttaatggc aaaaaagtca
    33601 taaaaactaa ggtggctgat ggtatacaca aagcggaaga acttatagac aaggctgtaa
    33661 atggagatgc tccaatttac catggaggag atggaagtca caacgaatca aatgaagaaa
    33721 gtgaaagtgg atttagaaaa gtatacaaac acttaatgaa tggtgtatct aatatgttac
    33781 catttgttat tggtggaggg atacttatag cgatagcctt tttacttgat gattatacta
    33841 ttaacccttc aaactttggt tcaaatacac cgatagcagc gttttttaaa gggataggag
    33901 ataaagcttt tggatttatg ttacctgtac ttgctggata tatagcatac tctatatctg
    33961 atagaccagc gtttgttgta ggatttgtag gaggtgctct agcaggtgat ggtggttcag
    34021 gatttttagg tgcactactt gcaggtttta tagcaggtta tttagtagaa gggcttaaga
    34081 aaatatttag tgtactacca gcttcattgg aaggaataaa accagtattg ttataccctt
    34141 tacttggaac acttttgatg ggaattataa tgacattttt agtaatacct ccagttacag
    34201 caattaataa tgcaatggtt ggatttttaa atggtttagg cggaacttca aaaatagttt
    34261 taggattagt attaggtgga atgatggctg tggatatggg tggacctgta aataaagcag
    34321 catatgtatt tggagttgca tcacttgaat cagggcagtt tgaaataatg gcagcagtaa
    34381 tggctggtgg tatggttccg ccacttgcta tagctcttgc aactacattt tttaagaata
    34441 gatttactaa agaggaaaga gattctggta aagttaatta tgtaatggga ttatcatttg
    34501 ttactgaagg agctatacct tttgcagctg gagacccact tcatgttata ccagcttgtg
    34561 ttggaggttc agcagtggca ggagcactta gtatgttgtt caacgcagct cttcgtgcac
    34621 ctcatggagg agtatttgtt ataccagtgg ttacccatcc atttgcatat atattagcta
    34681 tagctgtagg tgctttggtt ggaatgatgc ttttagcatt acttaaaaaa ccattaaatc
    34741 aagaagtata gcaattaaag gatattcaag aacttaaaat atgatgtttt ataaaaatta
    34801 atatattgct gaattatttt aaaataagga ttttattaaa ataaggattt tattaaaata
    34861 aggattttat gaggctgtta tataacgatt tgtaattgtt atcttgacag tcttttattt
    34921 ttatataagt aaaataagtg tgttttgctt tatttgtatt taaattgttt ttaagttaga
    34981 atataaataa aattatatat tattttaata ttcactcg
//
LOCUS       DAEQJM010000038        34843 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.038, whole genome shotgun sequence.
ACCESSION   DAEQJM010000038 DAEQJM010000000
VERSION     DAEQJM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34843
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.038"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(200..898)
                     /locus_tag="KRQ43_002243"
     CDS             complement(200..898)
                     /locus_tag="KRQ43_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2742596.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHEYQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTILENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
     gene            1156..1713
                     /locus_tag="KRQ43_002244"
     CDS             1156..1713
                     /locus_tag="KRQ43_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2742597.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKATIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLADSIDTVLLGIHKKYD"
     gene            complement(2082..2555)
                     /locus_tag="KRQ43_002245"
     CDS             complement(2082..2555)
                     /locus_tag="KRQ43_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2742598.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFEDIAVEQIVDGIRFTPMKLLI"
     gene            2858..3622
                     /locus_tag="KRQ43_002246"
     CDS             2858..3622
                     /locus_tag="KRQ43_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HBH2742599.1"
                     /translation="MQIIDININNIDSRHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     AFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKGFCLADTSEPNYELLYFPFTDNAPIPCF
                     KNCVKKRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKI"
     misc_binding    3845..4058
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4312..5346
                     /locus_tag="KRQ43_002247"
     CDS             4312..5346
                     /locus_tag="KRQ43_002247"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBH2742600.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKNI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEVL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            5388..6605
                     /gene="argJ"
                     /locus_tag="KRQ43_002248"
     CDS             5388..6605
                     /gene="argJ"
                     /locus_tag="KRQ43_002248"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HBH2742601.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKENDVLVASTGVIGKPLNINLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            6620..7480
                     /gene="argB"
                     /locus_tag="KRQ43_002249"
     CDS             6620..7480
                     /gene="argB"
                     /locus_tag="KRQ43_002249"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBH2742602.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGMDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            7510..8697
                     /locus_tag="KRQ43_002250"
     CDS             7510..8697
                     /locus_tag="KRQ43_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HBH2742603.1"
                     /translation="MNNNNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            8806..9828
                     /gene="argF"
                     /locus_tag="KRQ43_002251"
     CDS             8806..9828
                     /gene="argF"
                     /locus_tag="KRQ43_002251"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBH2742604.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAYVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQKIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            9955..10572
                     /locus_tag="KRQ43_002252"
     CDS             9955..10572
                     /locus_tag="KRQ43_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HBH2742605.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     TVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(10792..11490)
                     /locus_tag="KRQ43_002253"
     CDS             complement(10792..11490)
                     /locus_tag="KRQ43_002253"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBH2742606.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(11652..12869)
                     /locus_tag="KRQ43_002254"
     CDS             complement(11652..12869)
                     /locus_tag="KRQ43_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HBH2742607.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(13060..13473)
                     /locus_tag="KRQ43_002255"
     CDS             complement(13060..13473)
                     /locus_tag="KRQ43_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2742608.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKTEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
     gene            complement(13966..14604)
                     /locus_tag="KRQ43_002256"
     CDS             complement(13966..14604)
                     /locus_tag="KRQ43_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH2742609.1"
                     /translation="MKGLILKDLLNLKGNVKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            complement(14604..15467)
                     /locus_tag="KRQ43_002257"
     CDS             complement(14604..15467)
                     /locus_tag="KRQ43_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742610.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRNPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            complement(15464..15838)
                     /locus_tag="KRQ43_002258"
     CDS             complement(15464..15838)
                     /locus_tag="KRQ43_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2742611.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            16205..16609
                     /locus_tag="KRQ43_002259"
     CDS             16205..16609
                     /locus_tag="KRQ43_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HBH2742612.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNICFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            16626..17222
                     /locus_tag="KRQ43_002260"
     CDS             16626..17222
                     /locus_tag="KRQ43_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742613.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            17259..19853
                     /gene="clpB"
                     /locus_tag="KRQ43_002261"
     CDS             17259..19853
                     /gene="clpB"
                     /locus_tag="KRQ43_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBH2742614.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSDDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(20050..21477)
                     /locus_tag="KRQ43_002262"
     CDS             complement(20050..21477)
                     /locus_tag="KRQ43_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2742615.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            21619..22515
                     /locus_tag="KRQ43_002263"
     CDS             21619..22515
                     /locus_tag="KRQ43_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH2742616.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDFLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            23180..23320
                     /locus_tag="KRQ43_002264"
     CDS             23180..23320
                     /locus_tag="KRQ43_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742617.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(23317..23688)
                     /locus_tag="KRQ43_002265"
     CDS             complement(23317..23688)
                     /locus_tag="KRQ43_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2742618.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            24237..24494
                     /locus_tag="KRQ43_002266"
     CDS             24237..24494
                     /locus_tag="KRQ43_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742619.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(24604..25284)
                     /locus_tag="KRQ43_002267"
     CDS             complement(24604..25284)
                     /locus_tag="KRQ43_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH2742620.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            25544..25843
                     /locus_tag="KRQ43_002268"
     CDS             25544..25843
                     /locus_tag="KRQ43_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742621.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            26167..27822
                     /gene="ilvD"
                     /locus_tag="KRQ43_002269"
     CDS             26167..27822
                     /gene="ilvD"
                     /locus_tag="KRQ43_002269"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBH2742622.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIEFNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            28166..29104
                     /locus_tag="KRQ43_002270"
     CDS             28166..29104
                     /locus_tag="KRQ43_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH2742623.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
     gene            29580..30008
                     /locus_tag="KRQ43_002271"
     CDS             29580..30008
                     /locus_tag="KRQ43_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH2742624.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(30161..30955)
                     /locus_tag="KRQ43_002272"
     CDS             complement(30161..30955)
                     /locus_tag="KRQ43_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase"
                     /protein_id="HBH2742625.1"
                     /translation="MEKYATMIKEKLNEGKVLCGVAVSLSDSVVSELIGISGYDFIWI
                     EGEHSALDRKDIQQHMIAAHAGGAASLVRLVNSDPDLVKPIMDMGTDIICFPFINTVE
                     DAQKAVAACTYPPNGIRGYNPQRASYYGNMNYFDYVKNANNETLKMMLIEQKAGYDNL
                     EEIVKVEGIDIIALGPGDLSLDMGFSGYMNRIEIKDMISHAAEICKKYKMPFIIFPTI
                     EKKSIEEWVNIGANMLCFAQDTTFITYVINQLLSFYNEIVPIQKQH"
     gene            31104..31472
                     /locus_tag="KRQ43_002273"
     CDS             31104..31472
                     /locus_tag="KRQ43_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2742626.1"
                     /translation="MKYSITDVSKITKISSSAIRFYEEKGLLLPINRKPSGVRYFSEE
                     DVERLIFIKELKNTGLSIKDIHECFHFCDMGDGTIDKRIQLFQQHKQNIKNKIHELES
                     CMDKIDEKIYYLKEKKMCKK"
     gene            31701..33356
                     /locus_tag="KRQ43_002274"
     CDS             31701..33356
                     /locus_tag="KRQ43_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2742627.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQMIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKGI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVDSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            33415..33555
                     /locus_tag="KRQ43_002275"
     CDS             33415..33555
                     /locus_tag="KRQ43_002275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742628.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGTYKHACSYGNWSASTSCHW
                     YK"
     gene            33500..34168
                     /locus_tag="KRQ43_002276"
     CDS             33500..34168
                     /locus_tag="KRQ43_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH2742629.1"
                     /translation="MPVLMAIGVPVHLAIGTNKFAASAGCISSAYRYAKSGKINNDLL
                     KKLVPFTIIGSVLGVRCVLSISEEILNVLVVVMILIVAIYTFISKNLGQEDNFEAVNK
                     KNLRLGMLMALIMGFYDGFFGPGTGTFLTFGFIKIYGYDFLHASANTKILNLTSNITS
                     LLLFMINGQVDYKIAIVFALVMIMGAYVGAKVAIKKGSKMIKPIFLVMALFMVVKLVY
                     QTLV"
     gene            complement(34684..34749)
                     /locus_tag="KRQ43_002277"
                     /pseudo
     CDS             complement(34684..34749)
                     /locus_tag="KRQ43_002277"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        13817 a         3794 c         5382 g        11850 t
ORIGIN      
        1 gaaagagagg gagacaatat tatatccctc ttttttctat aataactaat tattaaaaaa
       61 ttattaatac tctatatact tttaatttct ttaataataa ctaatttatt ctttatgtag
      121 ttattttaat aatgctaaaa taaaattaat taaataacat ttataaataa tttaatcata
      181 ttaataatat aattattttt tatttaacta aagtatttaa ccattcatat aatgaattta
      241 attcttgtgg tgtgttaaac caatgtttgc cattttccag aatagtaagg ttgcaattaa
      301 acttttctac aaatttctct acaacaccga tttcagtaag ttcatcatgt ttaccatata
      361 atatttttgt tggtacattc cattgagtga taggatgttg ttttacatat tgtagatatt
      421 cccatgaaag agtatgccca aatgaagttg ggataattag ttcatgttta agctgttctt
      481 ctgatacatt tgcccaaagc atcatatttg aaatgagctg ttgcatatct agaattggag
      541 atacaaaaat acactctctt aagttctctt tttcaaagct taacatacta aaccatgctc
      601 caatgctatt tgcatataac gaaatttgat tccagtggca ctttgcatat tccataatag
      661 atactaattc tggaacaaca tgccatgggt taaatgaatt tttttctctt ttacgttctc
      721 catgttcagg caaatcaaca cttaaaactt gatactcatg tggaactgca atattagcaa
      781 aagcttcagc ctcctcttta ttgccgcatt gtccatgtat gtaaatatat aatttacttg
      841 aaggatttcc ccaaaggatt gaaggaactc catgaatttc gaaatatttt ttttccataa
      901 aaatctcctt tcagtttgat atattagtga ttgttgaatt aatcaaacta taaaataatg
      961 ttgtaatata taatttaata taatactaat tatattagta ttaaaactaa ttcaattagt
     1021 attatattaa attataatta aactgtcaag attttataag agtataaaga attttataaa
     1081 ttacaataat tgacgaaact aattagatta gctaaactaa taaagtaatt aattttaaat
     1141 gaaagaggga aaatcatgcg tgttagtaga gaaatagtta tacaagctac atcagatata
     1201 gttaataaag atgggcttaa caaagtttct ttaaaagtta ttgcagaaaa gctaggaata
     1261 cgtacaccat ctttgtacaa tcatatagaa agtctagatg atttattact tgaagtagct
     1321 cataaaggaa tgagagagat gaatagtcaa atgataaagg cgactattgg aaattttgga
     1381 gatacagcta taaagtgtat aagtatagca tactttaatt ttataatttc taatcctggt
     1441 gtttatgaaa caattcagtg ggctacttgg catggaaata atgaaacatt agaaatcttt
     1501 gatgaatata aatccttatt agaaaaactt attctttctt gtaatctaaa tacaaagaat
     1561 acaggtgaag tattaaactt aataatgagt gtacttcatg gttattcgac tttgcaactt
     1621 gggaaatcac ttttgagtaa agaagaagct ataaaaggtt tagccgattc tattgatact
     1681 gtgttattag gtattcataa aaaatatgat taaggaggta aataaattat tttaacttat
     1741 ttattaaaca cttcattacg gagcatgtaa attaaaattt tatcatttgt accaaaggaa
     1801 aatcaacagg agaacagtat attttaagaa tatttatttt caaatgccca atattgttta
     1861 caaagaagag atataaagag aaacaacata gtttatgttt aataattgaa ttaatttata
     1921 tgttaatcaa aaaggatatc aaaaaataaa ttatagttca tattagtaag gcttttaaag
     1981 tatattatta aaaaacaaaa aagatagtat tattttaaat cttggtttaa aagcaaagta
     2041 actataaaat atttaagaga ctttgctttt tatttaattt attatattaa caatttcata
     2101 ggtgtaaaac gtataccgtc aacaatttgc tcaacagcaa tatcttcaaa tcctaattta
     2161 tgataaactt caacagcata aggtgatgaa tttacagtta tttcagttaa attaaattta
     2221 ttacaaatac agtattgtat gcctgtagtc attaattttt ttgcaacacc atgtttatga
     2281 tagtttttat ctacaaataa catacatata tgatttaaat ttctaatagc taagactcca
     2341 ataagttttt tagagtcaaa acaaccccaa aagaagagtg ttttttcttt gattttttca
     2401 ataatagaat tatattctat aaattgatga aatgtcgtaa ttccttcatc acaataatct
     2461 ggagattcaa attcttcaaa tacattccag attaagtcta atgcattttt aatatcatct
     2521 tcttttaatt ctcttattaa gtattctttg aacattataa acaacacctt tattattatt
     2581 ttaattataa ttataattat atatcttaaa taaatttaat tcaatacaat ttgttttata
     2641 aatttagaat attatgataa tatatagttt atatatagtg tggttagacc tagaatgtat
     2701 ttaattatat atgcaatttg ataattcaaa taatctaaaa ataatattat gtaaaataaa
     2761 aatatatatg acatgatgtt gttgtattca aaatattaag ataaaaatat atagaatata
     2821 tttaaaaatt attatgtaat tagaaaagga gataagtatg cagattatag atataaatat
     2881 aaataatatt gacagtagac atatatgctg ttcaatttct gaaaaaaaag gagaaaattg
     2941 tgttttttct aaaaaagctt ggatgaaaaa taattttgat aaaggtctag cctttaaacg
     3001 atttgatgta agaggtaaag cttttataga atatattcca gcagaaaatg catggtgtcc
     3061 tattactgcg gacaattata tatttattaa ctgtttttgg atatctggaa aatttaaggg
     3121 tcaaggatat tctaatctat tgctacaaga gtgtgttgat gatgcaaaat caaaaggtaa
     3181 atatggatta gttgtgcttt cgtctagtaa aaaaatgcct tttttatctg atgctaaata
     3241 tctaaaatat aagggctttt gtttagcaga tacatcagaa ccaaattatg agctattata
     3301 ttttcccttt actgataatg ctcctattcc atgttttaag aattgtgtaa aaaaaagaaa
     3361 attaaatgag aacggtatag ttttatatta cagtaatcag tgtccacata cagaaaaata
     3421 tgctcctatt ttgaaaaaaa ttgcaaattc tagaggtatt gatgtaaatc ttataaaatt
     3481 cgaaacagca aaagaagcac aaaatgctcc tgcaccattt actacataca gtcttttttt
     3541 taatggtgaa tttgtaacca acgagatact ttctgagaaa aagattgaga aatttttaga
     3601 taccaacatt aaaaaaattt aactaaaaat agatgtaaat attgtatttt gagattacat
     3661 tattttataa tccaatatat tttggaaatt tcttaagttg atgaatgata atataaagat
     3721 tataactcaa tttagataca aaatgctgga aattaaccat atagaaaata tttccaaaaa
     3781 tttaaaaatt atattgacaa agttaaaaaa ataaactatc atataaaaca ataagaaaat
     3841 aaattgaaat cctgtgaaaa agagagtagc ataaagctag ttgatagaga gctgggaatg
     3901 gtggaagcct agtaacgaat tttattgtga atagagcttt ggaggagatt accagaagta
     3961 atagtatggt aattggtgaa tctcgcctta agagattaga gtgggtaaga ttatcttatc
     4021 aattagagtg gtaacgcggg tgtatattcg tctcttggtc tttgaccaag aggctttttt
     4081 aattttaaat gtacattttg tagatacttt ttaatttgag ttttaatgat tattgtaatt
     4141 ttaccaatga gagtggtacc gcggaaaatc gcctcttagt atttataatg ctaaggggtt
     4201 ttttgtttta attagaatat tttaatctac atattatcaa atgattatca tatagtaaag
     4261 tggaaagata gaattttaat actatttgaa tataaaaatg gagggaacaa aatgaataaa
     4321 ataaaagttg gtattattgg cgcaactgga tatgtcgggg cagagttgat tagattatta
     4381 atgaatcatg ataaagtcga agtgacagca ataggttcaa attcgtatgt tggaaaaaat
     4441 atagttgata tatatccaag tataggatat aaaaataaca tgatatgtat agaaaatgaa
     4501 aaagttatag atatgtgtga tgttgtgttt acagcccttc cacatggagt tagtgaaaag
     4561 tttgtaataa aagcaattaa atcgaaaaag aaagttatag atttaggtgc tgactttaga
     4621 ataaaagatg aagaagtata tagtaaatgg tatggagtat cttttataga taaaatctta
     4681 cataaaaaag ctgtatatgg attaagtgaa atatacaaag aagatataaa agatgcagat
     4741 ataattgcaa atcctggatg ttatccaact agtatttctt taccattgat gccattacta
     4801 agttctaaat tgataaaaaa taataatata ataattgatt ctaaatcagg tcttacaggt
     4861 gctggtagag aattatcgat tagtagtcac tttacggagg ttaatgaaaa tatcactgca
     4921 tataaaatag ggaaacacag acatactcca gaaatagaac aaaatttaag tgaatcctgc
     4981 aaagaaaaag taagtgtagt ttttacacca aacttaatac cagtaaatag gggaatctta
     5041 tcaactatat attgtacaaa agaagataat atttctataa atgatataca tagaaaatta
     5101 actgattatt atgaatttaa agaatttata gaagttctcc cattagataa ggtagcttct
     5161 ttaaagaatg ttaggttctc aaataaatgt gtcatatcat tacatgaaaa tggagataca
     5221 ttgataatct gttcagctat agataatatg attaagggag cagcaggtca agctatacaa
     5281 aacatgaata taatatttgg tattgaagaa aatacaggtt taaaaaatat tgcaccatca
     5341 ttttagtaat gaaaaaatac taaactcata taattaggag gataaatatg gagattataa
     5401 agggtggagt tacagtttca gaaggatttt ttgcttcagg gattcactgt ggcttgagaa
     5461 aaaataaaga aaaaagagat ttagctttgg tttattcaga tgttttatgt gatgcagcag
     5521 cagtagtaac tcaaaataaa gtaaagggca atcctgttta tgttacacag gaacacatta
     5581 aaaatggaaa agcacaagct atcatagtaa atagtgctaa tgctaatacc tttaatggaa
     5641 aagaaggact tataaatgct tataaaatgg ctaaattcac tagtgataaa ttaaatatta
     5701 aagaaaatga tgttttggtt gcatctacag gtgtcatagg aaagccatta aatataaatt
     5761 taatagaaga aaatatggat gaattagtga ataatctaag taaacaaggt catattggag
     5821 caagagaagc tattatgaca actgatatta taaaaaaaga aatagcagta gcaataatgt
     5881 atggagataa aaaaataact attggaggta tggcaaaagg ttctggcatg atacatccta
     5941 atatggcaac aacgttagga tttataacta cagatgcaaa tattgatgga gttttgctaa
     6001 aagaagcttt gaaaattgct gttgataaaa gttttaatag agttagtgta gatggagata
     6061 caagtactaa tgatatggtg atgattctag caaatggaaa agcaaaaaat gatagaataa
     6121 acaaaaaaga tgaacattat caagtatttt tgagtgcact tacatatgtc tgtatagaac
     6181 ttgctaaact tgttgcaaaa gatggagaag gatgtacaaa actaattgaa tgttatataa
     6241 atggagcatt aagtgaagaa catgcagtaa aattagcaaa aacagttata tcttcttcat
     6301 tagtaaagac agctgtattt ggagctgacg caaattgggg tagaatactg tgtgctttag
     6361 gttatgcagg tgaagaaata gatatggaaa aagttgatat tatttttgag agtatgaaag
     6421 gatatattga agtatgtaaa aatggaaatg gattagattt taatgaggaa aaagcaaaaa
     6481 aaatccttga agatgacgaa ataagtatat tagtagattt aaatatgggc aatgccagag
     6541 gaaatgcatg gggatgtgat ttaagctatg attatgtaag aataaatgga agttatagaa
     6601 attaggagga tatactttaa tgattaatat agaaaaagca aatacactta tagaagcttt
     6661 accatatata gaaaaacatc agggaaagac tattgtagtt aagtatggtg gaagtgcaat
     6721 gaaaaaagat ggtctaaaag aatctgttat ggaagacctt gtattaatga gttatgttgg
     6781 aatcaatata gttttagtac atggtggagg ggcagaaatc aataagatgc tagcaaaagt
     6841 ggatatagaa agtaaatttg taaatggtct tagatataca gatgaagaga ccatggaaat
     6901 tgtaaaaatg gtacttgctg gaaaggttaa taaagaccta gtaaataaaa tacatacaaa
     6961 aggtggaaaa gcagtagggc tttgtggaat ggataataat atgattttat gtgacccata
     7021 taaaaattat gaacttggat ttgtaggaga aatcaaaaaa gtaaatgttg agcttataga
     7081 atcttgtcta aagtcaggtt atatttcagt aattgcaact ataggtgttg gagatgatgg
     7141 agagacttat aatataaatg gtgacacagc agcttctgct atagctaaag agttaaatgc
     7201 agataaattg atacttctta cagatgtccc tggtttgtta agagagccag atgaagaaaa
     7261 atcattaata acagaagtta tattagagga tgttgataaa ttatttgaag aaggtataat
     7321 tactggaggt atgataccta aaatagaggg atgcgtagat gccttaaata acggagtaaa
     7381 tagggtacat attttggatg gaagagttcc acattctata ataacagagc tatttactga
     7441 tagtggaata ggtacattaa taagaaaaga aaatgaataa aattataagt ttaagagggg
     7501 agaataagaa tgaataacaa caatacaatt tcaaaatgga atgaatattt tatagataca
     7561 tataaccaac ccaattttgt catagattat ggtgaaggaa gttgtttttt tgatactaat
     7621 ggcaataaat acatagattt tacaagtgga tatggagtat cttctcttgg gtatagtaat
     7681 agtaatttaa agaatgctct aaaagagcaa gtagataaat tattacatac ttcaaattta
     7741 tattttaatg agccagtgtt gtattcagga gagaaaataa ttaattcaag tggaatggct
     7801 aaagtatatt tttgtaattc tggaacagaa gcaaatgaaa cagcattcaa aatagcaaga
     7861 aagtatagta gtgacaaata tggtaatggt agaggaacta tcataagttt aaaagactct
     7921 tttcatggta gaacaatgat gtctttaatg gcaactggta tggacaaata ccataagtat
     7981 ttttatcctc ttcccgaagg ttttaaatat atagaaagaa ataatattga agatttaaaa
     8041 aataatcttg attccacagt ttgtgcaata attcttgaag cgattcaagg cgaaggtgga
     8101 gttaatgttc ttgaaaaaga ttatgttttg gaaatagtaa aaatatgtca agaaaaggat
     8161 attgtagtga tttttgatga agtccaatgc ggtataggaa gaactggtaa actttttggc
     8221 tatgaatatt ttgatgtaaa accagatata gttaccgtag caaaagggtt gggagcagga
     8281 ataccagtag gaggagtatt ggtaaataaa aaactttcaa aagtactagg aaaaggagac
     8341 caaggtacaa cttttggagg taatttatta gctatggtgg cagcttcagt tgtattagat
     8401 gagatatcta aagatggttt ttataatgaa gtattagaaa aaggaaatta tataagaaaa
     8461 tctattgaaa gttttaataa taaagttgta ttaaagacaa aaggtattgg tctaatgata
     8521 ggaattgaaa ctaatattga atctagtatt atagaagaga aagctagaaa aaaaggattg
     8581 cttattttga ctgctggaaa aaatgtattg agatttttac caccattaac aatcagttat
     8641 aaggaaatag atgaggctct tgaaatccta aaagatatat tactagagat taactaaata
     8701 ttcaaaaaat agttaattaa agataaaaat tagaagtaaa taaaaaagta aagtgctaac
     8761 aagtttaatt gaatttaaga agtttataag aaggggcgaa ttaatatgaa taatataagt
     8821 ttaaaaggta agagtttttt gacattaaag gattttacaa aagaagagat tagatattta
     8881 ttaactttat caagttattt aaaaactaag aaaaaagttg gcataaaagg cgatttgcta
     8941 caaggaaaaa atatagcttt attatttgag aaaacatcaa caagaactag atgttcattt
     9001 gaagtagcag ctcatgatga aggagcatat gtaacttatc taggtccaaa tgattgtcat
     9061 atgggtaaaa aagagtctgt atcagataca gcaaaagttc taggaagatt ctatgatgga
     9121 atagaattta gaggctttaa acaagaaaca gttgaaagtc tagcaaaata ttctggtgta
     9181 cctgtttgga atggacttac agatgaatat catccaacac aaatactggc agatttttta
     9241 acagtaattg aaaatgtaga taaagatttg aataaagtta aatttgtata tgttggtgat
     9301 gctagaaata atatgggaaa ctcactgatg ataggatgtg ctaaaatggg aatacatttc
     9361 gtagcactag cacctaagga actttggcca aatgaagaat tggttaagga aatgaaggaa
     9421 atagccaaga aatccaaagg agatataatg ttgactgaaa atattgatga tgttaaaggt
     9481 gcagatgtta tatatacaga tgtatgggtt tctatgggag aagaggagca atatgaagca
     9541 agaataaatc aacttaaaga ttatcaagta aatatggata tgataaagaa aactgaaaat
     9601 gaaaatgtta tatttttaca ctgtcttcca gcatttcatg atttagaaac taaggttgct
     9661 cagaagattt atgaaaagtt cggattatca gaattagagg ttacaaacga ggtatttaat
     9721 tcaaaatatt caaaggtatt tgaagaagct gaaaatagaa tgcatacaat aaaagctgtt
     9781 atggtttcta ctatgactga tgtaaatatg aacaataatt taatatagat atgttttaat
     9841 atagacttta ctttaatgaa aatttataaa atattttaaa tatattattc aaaaactctc
     9901 attatatgtt aaaataactt atgtatcaac aaattaagag ggaggatttg agatatgaaa
     9961 aaaatcatat tagctttaac aactttttta ttagcaatat ctttaacagc atgttcaagt
    10021 gcaaaaccag aagatacaat tgatagtttt tttaacagtg cgaaaaagtt tgactttgaa
    10081 ggcatgaata aggtaatgga aaataatgac gaaaaatata aggatatatt aaaggaatta
    10141 gatacaaaag acccaaatgc ccaatatgtt ttagattatc taaaacagaa tgcatctaaa
    10201 atcacgtata caataaaaga cagcgaggtt aaaggtgata aggctacaat caaagtagaa
    10261 tgtaaattta tagattcaac accattactt caagaaatag tagctgaggc atttacaaag
    10321 atgattggta tgagtttttc aggacaagac ttaactgatg agaaaacaac tgaaatgtta
    10381 gtatcaatta tgaaagaaaa acaaaaaagc gttaaagaga cttatgttac aaaaactgta
    10441 gagtttgaat gttctaaaaa ggataataaa tggataataa gttcagtaaa tgatgcagta
    10501 gctgatgtat tgttatctaa tcttgttaca gcaggacaag aattttctaa ctctatgaat
    10561 acacttgaat aatattgttt aggtgtagta aagtaataaa tatatgatta tttttataaa
    10621 taaacatata aatatttatg aaggatacca tttttggtat cctttttatt aatataatga
    10681 aatacatggt taatttctat attgtcaaga aactatgata tatgttataa gtctatacta
    10741 tttaaaataa acttataaca tatatttttt ataatatagt gcatgaaaaa tttatttaac
    10801 taattttaga tatttattga caactgattc agccaagcat tttgatgaat caacaatatt
    10861 tattgaagga tatgattttt ctaaaactac atttaaatca gtacaagcaa ttactatatt
    10921 ttctatagat tcatttttaa catcttcgat aagtttattc caaatatcaa tattgtgtgg
    10981 attttcttta tccattttta tattttgaat aagattgttt aattttattt gccattcatc
    11041 tttaaatata aattcatgtc cattatgtat tataccattc tggtaaattg tagactcaaa
    11101 agttgaacta gtcgaaaaaa gagttacttt ttgtgagata gtaggtaatt ttttaactgt
    11161 ttcttctaca atatttaata ttggtatatt aatagactct tttaattctt taaagtatat
    11221 atgtgctgaa ttgcatggca ttgcaataaa atttacacca gttgattcaa gcttttgtaa
    11281 tccatcaatt atagtttctt tcataagttc atgatttatt ggacggtcaa tataaaatgg
    11341 ggtaggtaat gaatatatca tcatctttgg aaattcatca tcatattttg ctccatattg
    11401 agattgacac tcatcaataa ttaaatcaac aaaaggggct gttgaccttg gacccattcc
    11461 agccaaaata ccaattaatt tttcattcat aaaaattatc tcctttatat ataaatatat
    11521 ttatgtataa aataaaaatc tataaaagca taaaattata ttttataata gattatattg
    11581 tacacttgta taatataaat ataaagtgat tttttagatt atatatttta atatactttc
    11641 ttatataaaa attattttaa atcaagatta tctagtattt ttaaaaatat ttttacagca
    11701 gtatccaagt catctacaga aacactttca ttaggattat gacttacgcc cccagcacat
    11761 cttataaata ccataccaat atcagttata ttatccattt cctgagcatc atggccagca
    11821 ccactataaa tataaaaagg attaagattt aaatctataa aacttttttc tatgattttt
    11881 gttattttat tagaacatgg tacaggaaca ttttcaaaag caagttcact tgtataatta
    11941 agttttctat tttcacatat atgtgatatt tcattaaata tcttttctac agaattatca
    12001 agaatttctt gtgaacaaga gcgtacatcg agtgtaaatt cagctctttc aggtaccaca
    12061 tttgatgaag atggatagaa attcatcttt cctacagtag caaccaaatc agcagtcgtt
    12121 ttagctactt tttcgatagc taatacacat tcacaggcac aacatccagc atcaagtctc
    12181 atattcattg gaagtgtacc agcatgtcca gacttaccat ttactgatat cttaaaactt
    12241 ttaaatcctg taatacttga tacaattcca gcaggaagag attcattttc taaaacagga
    12301 ccctgctcga tatgaaattc taaatatgca tctacatctt ttctaggatg caaatttgtt
    12361 aagttttttg tattaaatcc aaactttgtt acagcttctt caagtgtaat tccattttca
    12421 tcaacagatt taagaagttc ctctttaaaa gtaccagcaa aaactttact tcccattaaa
    12481 gaagtttcaa atctagttcc ttcctcttca gcgaaagcaa ttagcttaat attgaaagga
    12541 taagacctat tattgtgttt tgcttcttca agaccaacta gaggcactat tatacctaac
    12601 ataccatcaa atatacctcc acactttaca ctatcttgat gagatgcaac tactaatgtg
    12661 ggagcatttg gaaagcttga tttatatgta cctataacgt ttccaatgtc atcaatttca
    12721 atatcaagat ttaaaccttc catccatgaa ctaattaaat caatagattt tttatgttct
    12781 tgagtcaaga taagtcttgt aagaccattt gttgttgaac ttatttttcc taatgtttgt
    12841 agataatcca tacatttttt tcctaacata tttacctcct aaaaatataa tttttattta
    12901 agctaagatt agcttttata cttataattt ttgaactttc aaataatttt gtatgtatag
    12961 taaaatacta ttttagtatt aataatgata taaaaacata aagtctgtag acgaagagca
    13021 gaagttttaa gttaaaaata taaaatatga tttttattat tatagtattt ttctataata
    13081 atatctcttt ccagttagag gataattttc aagtgaaaat actttatggt atccaaattt
    13141 ctcataaaat ttaggtgctt gaaaactgaa tgtatctaaa aaaacatatt tacaacctcg
    13201 ttctttagca attttttcag tcttatataa aagttgactt ccagtacctt tatatctaag
    13261 cttctcacta acccataagt attttataga aagccaatta ccatgagtaa cacctataaa
    13321 acctgcaaca attttacctg ctttatctcg aatatatatt cctaaatcca ctgggttttt
    13381 atcttcaagt ctagcaagat tatattttaa taatccttga aaaatagtat cttcatcttg
    13441 tttttctatt ttttctgtaa tttctaattc catatttgaa ctttctcctt gtataatctt
    13501 ttgtatattg gtatttttta ataaaatcag tagaaagaat atagtttaac attattctaa
    13561 taggcattta tgctaatgtc aaactaataa tacttattct taattttata ttgttgatat
    13621 taaatttttt aaaataaaaa tgtagtttaa gttatataaa aagaaatcat caataaattt
    13681 agtaaaccta aattgttgaa tattaaaata agttaattta atacataaaa actattttag
    13741 atgttattct attgctatgt tcaataatat cattagtagt tcaatttata aaatgaataa
    13801 attatataaa taagattaga aagtagtaaa tagtcttatt aaatataagt aataaaacaa
    13861 taaataccta gtagatatta ataataaaaa aataaaatac taccaaaata aacttgatag
    13921 tattttattt aaaatactta aatacagaga catgtatagt atattttata cttctttttt
    13981 actatagatt tttgatgata taaaatatga aatcacaaat agtaaaatag caacaaatgg
    14041 aagagaatat actagtgtat taagtataat ttctatagaa ataggtgaac taatattttc
    14101 taaaatactt ttaaaaacta ataaagctag tgttggaact aaaaagcata aaatcattaa
    14161 taaacgagct ctttctgtac caaatttata aataagtggt agaataaggc taccaaaaca
    14221 tactgaaatt gataagatta gtgcattaat aagtagtgtt tcatttaata taagtgtatt
    14281 tttaaaataa ccaatagtta cactaacaat aagtgaaaca agaacaccta taaagctaaa
    14341 tattaacata gttaaatatt tacttaatac aatatcattg cgattaatag gcattgtaag
    14401 tacataacta tcccatttat ttaaatcatc atatgaaaat gttgaaacaa tcattgtagt
    14461 acataaaact ataataacac ctataaagtt attaacattt ccatctccta aagaagacat
    14521 aaacccaaac ataatgatga ataaaagtat aaactttaca tttcctttca aattaagtaa
    14581 atcttttaaa attaaacctt tcattattta tcacctctca cataaaataa cataatttct
    14641 tctatagacg tattatcaac aatacaattt ggatttcttg atataaatct atgtttatct
    14701 ttaagaagta cttcatatcc aaattggctt ttacgataat atgaataatc ctctcttgaa
    14761 aggttatcaa aatcactagg tttacatttt aaaactccca tagtatcaat taattcatcc
    14821 ttattttcac taaatacaat ttttccttta tgtataaatg taatatagtc tgctatctta
    14881 tctaaatcac ttgtaatatg tgaagataag ataatagagt gttcttcatc ttgtataaaa
    14941 tctaaaaata tatctagtat ttcttcacga acgatagggt caagtgaact agttgcctca
    15001 tctagtatta ataattttgg tttatgagat aaggctacag caatactaag tttcatctta
    15061 ttcccctttg aaaactcctt aattaattta ttgtctggta ctctcaattt ttttaagtag
    15121 tctttaaata atgtgtcatt ccaattttta tagattttac tcatgatttt tgaaacatgg
    15181 tcagtgttta aattttcatg aaagttgctt ccctcaaata caaccccaat ttgctcttta
    15241 atttcttttt catttttttt actatcaaga ccaaatattt ctatatttcc actatcataa
    15301 gatattaaat ttaaaattgc ttttaatgta gttgtttttc ctgcaccatt ttcacctaca
    15361 aatcccatta cactcccttt tggtactgaa aaagatatat cttgtaggct aaaatcttta
    15421 taagttttat ttaaattttt tatagttatt gcatccatac ttatcattct cctttatata
    15481 ataaaaataa aatatctttt aattcgtcat atgtaatatc actacttttt gctgtatcaa
    15541 ctgctttttg taggtattct tcaattaaac gaaattgttc ttctttgaca aaatccatgt
    15601 ttttactaga tacaaaactg cctttaccag taactgtctc aataaatccg tctcgttcta
    15661 aatcgctata tgctcgtttt gtagtaatta cacttattct aagttccttt gccaatagtc
    15721 tcatacttgg aagagctgag ccttctggta actctccgct tataatcata cttttaattt
    15781 gtgtagtaat ctgttcatat attggcttcc cactcgaatt actaataact atattcaata
    15841 agtcacctcc ttaaattgta tatatagtat atacacatta tataaatata tatataatat
    15901 gtcaactgat tttagaaaaa actaattacc aatattatac atttaataaa tgtaatgtat
    15961 tttatgaaag gctgccatat taaatagatt taaatttttt taaaaaattt ataaatatta
    16021 ttcaaaaatc ctgccaataa attggaaata ctaaattaaa aaaataataa agtttagctt
    16081 atagctaaac aaaagtttac ttataaggta aactttttgc attttcagtt ttgacataca
    16141 tatttttttg taatatattt atattatcaa ttagagataa ggagagtgag aagagatatt
    16201 taatttggat aagacattaa aaaaggattt aaatcaggaa tatacagaga gcaaaagttt
    16261 agttatgaat aaaagtaagt atatgaatat ttgttttaag aattatatta aagtagtaga
    16321 aggaatgtat actaagaggg atttaattcc attaaaatta ataaactcta tggataaaaa
    16381 taataagatt agaaaaacat tatatgaatt atcttgtgaa tttgaatatc caaaaacttc
    16441 tttatcttca ttgtttacgg agttgaaaaa aatggatttt ttacaaagag tgaaaaatgg
    16501 tgagtatatg ataaatccac atatagcata taaaggtagt agagctgata aagaaagttt
    16561 attagcagaa tataatcaga taaaaagacc taataaggtt agtaaataag gaagaaggtt
    16621 tttatatgag tttaaaactt gatagaaatg ttctacagtg gtttgactat gtatttgaga
    16681 atgaaaaaac tagtttgaga cactataatt ttaattgtac actaaaggag attagttcta
    16741 ccagtttgaa caaagtagct tttattttag aaaaaaataa ctctaagtac tggaagcttt
    16801 attttgaaat accagctgaa gttactttaa aacttaagca aaacattcat cctttattta
    16861 gggaatatat atacgaacaa atatcactgt ataacaataa tcaaatttac aattttgtaa
    16921 attcaaacat attaaaagtg tttaataata ttgctattta tcaatataat attttagaaa
    16981 atctatacac tattgatttt aaaaagagtt ttatagataa atgtcagtat ttattaatag
    17041 gtgaaaaaag acttatagat gaagacttgt atttaatagc aaaatcaaaa gaagtattcg
    17101 atttttttaa ttcagatgga acatttaatt taacattgag tttcgatata caaaaaaacg
    17161 agaatttact tgatagtctt ttagagctta gaaaatcaat aattataaat gagagaattt
    17221 aatttatttg gatataatat taaaatggag ggatttatat ggacgtagaa aaaatgactt
    17281 taagagttca aaaaagttta aatgaggctt ataacgaagc agtaaaaaat cataaccaac
    17341 aagtagatgt aattcatctt ttctcagcac ttattaatca agaggatgga ttgataccaa
    17401 atataatcga aaaaatgaat atatcaattg attctttgag aaatactgta aactttgaaa
    17461 ttgataagct tccaaaagta tatggagaag gtgctgactc acaaggagta tcagctacta
    17521 gaaaaataaa tgaggtgctt ataaaggcag agagtatttc taaagaattt aaagattcat
    17581 atataagtgt agagcatgtt atgcttgcaa tgatggaaac agaatcaaaa tcagctgttg
    17641 gtaaaatatt aaaacaatat aatataaata agaatgactt tttaaatatt ttatcacaag
    17701 tgagaggtag tcaaagagta gaaacacaag acccagaagg cacatatgat gcacttgcta
    17761 gatatggaac aaacttagta gatttagcca agaaaaataa attagaccct gtaattggga
    17821 gagatgaaga aataagaagg attataagaa ttttatcaag aagaacaaaa aataatcctg
    17881 tattgattgg tgagccaggt gtaggtaaaa ctgcaattgt agaagggtta gcagagagaa
    17941 tagtaagagg agatgtccca gaaggtttaa aagataagat tgtattctca cttgatatgg
    18001 gagctttaat tgctggtgca aaatatagag gtgaatttga agaaagatta aaggcagttt
    18061 taaaagaagt tcaaagttct gatggaaaga ttatactgtt tatagatgag attcatacta
    18121 tcgttggagc tggtaaaaca gaaggttcaa tggatgcagg taatcttatt aaacctatgc
    18181 ttgcaagagg tgaattgaac tgtattggtg caactacttt tgatgaatat agaaagtata
    18241 tagaaaaaga taaggctctt gaaagacgtt ttcagcctgt aattgcagaa gaacctactg
    18301 ttgaagacac aatatctata cttagaggtt taaaagaaag atttgagata catcatggag
    18361 taagaataca tgataatgct attgtagcag cagcaaaact ttctcataga tatatacaag
    18421 atagattttt accagataaa gcaattgatt taattgatga agctggagct atgattcgta
    18481 gtgaaataga ttcattgcca acagaattag atgttgttag aagaaagtta tttacattag
    18541 aaactgaaag agaagcatta cttaaagaaa atgatgataa aagcaaatca agattggatg
    18601 atattcaaaa agaaatagca gagttaaaat ctaaaaatga tgaaatgaca gcaaaatatg
    18661 aaaaagaaaa gagtcaaata ttagatatta aaaacttaaa ggctcaatta gacgaagcta
    18721 aaggtaaagc tgaaaagtat gaaagagaat atgatttcaa caaagcagca gaggttaaat
    18781 atggtgaaat acctaagtta gaagaacaaa taaagcagta cgaagaaaat atgaatgatg
    18841 gttctgaaaa ttctctttta aaagaagaag ttactgaaga agaaatatct agcattgtat
    18901 caaagtggac aggtatacca gtaactaaac tagttgaagg agaaagagaa aaattactta
    18961 aactagaaga tgaacttcat aaaagagtta ttggacaaga tgaagcagtt acagcagttt
    19021 caaatgcagt aatacgtgca agagcaggat taaaagatga aagaaaacca attggttcat
    19081 ttattttctt aggccctaca ggtgttggta aaactgaact tgcaaaaact cttgctagaa
    19141 atttattcga tagtgacgat aatataataa gaatagatat gtctgaatac atggaaaaac
    19201 atgctgtatc aagactagtt ggacctcctc cagggtacgt gggatatgaa gagggtggtc
    19261 aacttacaga agcagttaga cgtgctcctt attctgtaat actatttgat gagatagaaa
    19321 aagcacatga ggatgtattt aacatgttct tacagatatt agatgatggt agacttactg
    19381 ataataaagg taagacagta gactttaaaa atactcttat aataatgact tctaatatag
    19441 gaagtaatta tctattagaa gcaggaggaa atataacaga gactactaac aatttagtaa
    19501 tgaatgaaat gaagcataga tttaaacctg agtttttaaa cagagtagat gatattataa
    19561 tgtttaagcc tttagaccaa gaaaatatca agaaaattat agatatattt atgaaagatt
    19621 taaaaaatag attaaaagaa aaagatatta ctattgaagt tacaaattca gcaaaagatg
    19681 ttatggtgag agaaggatat gaccctgtat atggagcaag acctcttaag agatatatag
    19741 gaaatacatt agaaactata attgcaaaga aacttattgc tggagatgtg tataatggat
    19801 gtactatagt tatagatgga aaagatgaaa atattgaagt tttagttaaa taataaaaga
    19861 atcagttgag cataatatac taaatatttt gctcagctga tttttattta taaactatag
    19921 gaaaagaaat attttatcaa attaataaaa catttttaag tcaatatgtc caaattaaat
    19981 ttaactcaaa ggaagtattt tagtaagttt cttataatat aatcataatt tgaatataat
    20041 tataaaaaac tactgttcat ttttattata tttaaataaa taaaagccaa ttaatattgc
    20101 acctattaag caaacaagtg taacaataat ataaacattt ctcattccaa atacaaatat
    20161 tttatcatta ttaatcacat aatcattgac cctatatcca gctttaatac tcataaaatt
    20221 atataaaagt gttgtagaaa tagtaatacc tataacttgt cctaaatttc ttacaaggga
    20281 atttatgctt cctacaactc ctagcttact tctagaacag cttgacatta tcaaagcatt
    20341 gttagcaggt tgaaatatag cttgtcctat tgatattatc gatatataaa ttacaaataa
    20401 aataagggca gaactttctt tcaatcttga cattagaaag aatccaaaac tcataacgag
    20461 aagaccaatt aaaataattt tttctgactt gattttatct gatatattcc caaatatagg
    20521 tgaaaaaatg gctaaaatca aaggtgatag tatcataaat aaacctgctt gaataggggg
    20581 aagtttcata gtactttgta agtaaaatgg aattaaaata cttgatgatg caatacaaat
    20641 gaatgatgta agagcacaaa ttaaattcaa tgaaaattta aaatttctaa aaatttcaag
    20701 atcaagaagc ggttgaggat gttttttttc taatatcaaa aataatataa taaaaataat
    20761 tgataataat agtgcaatta atatatatgg atttagtaat cctgtttgtt gagcactaat
    20821 tagagcacta aaaaataatg ttgttcctaa aaattgaagt atagcaccag ttttatccat
    20881 attttctgaa gattttttac tattaggaag aaattttgta tttaaaaaga ttacaataag
    20941 accgattgga atatttataa aaaatataac attccaatca aatattgaca aaataaatcc
    21001 tcccacagat ggtccaacca tatttccaat agcaactgca gtaactagaa tccctagggc
    21061 ttttcctctg ctttcttttg gaaatagttc tgtgataatt ccatgattgt ttgccatgta
    21121 ggcagaagcg cctattcctt gaataaagcg gcaaactata agtaaagtta aagaattact
    21181 taatccacat agtaatgaag ctgatgtaaa gagaatagta cctacttgga atactcttga
    21241 tttaccaata atatctccaa gtcttccaaa aaataatagt gttgaacaaa taataattga
    21301 gtaacttgct attacccatt caatagatgc tagagataca tttagtttgc ttgcaagaac
    21361 tgggagagca acatttataa tactcgaatc taatgttgcc ataaaagtca tggcaatgac
    21421 tacaaataaa actgtgattt tttttctatt atcatctttt ttaaaagagt ttgtcatttt
    21481 tattacctcc ttattataat gactggcatt atgttaatgt ttacaatgat agttacattt
    21541 tatataatag cgatatgaaa taatgaatac aataactata ttgcttataa ttagcactat
    21601 tttgatgagg ggggaataat gaaggataaa aatacatatt ttaataggaa aggtcaagaa
    21661 aactttatag atattttttt aaaggatgac attaaaaaag gagcaaactt taaaagacat
    21721 tggcatgagc atctacaaat atattatttt attgatggta tagcatatct tgaatgtgga
    21781 ttggataatt ttaaggtagt gcctggaaat attgtaatag caaacagtaa tgaattacat
    21841 tatttagaaa gcttatcaga taatttaaaa ttctatagta ttcgtattga gcccacattc
    21901 ctttttagta atcaagttga tttgttacaa actaagtact tagcaccatt ggctttaaat
    21961 catattgtat ttaataattt aattcaaaat gattttctga ttttaaaatg tattacaact
    22021 atacttgatg aatatcacaa taaagaagtt ggatatgagt tatctataaa agctaatatc
    22081 tatcaattaa tagtactctt attaagaagt catattgata aaatatattc tgaagatgaa
    22141 tttataaaaa gaaagtattc tttagaaaaa tttgaatgta tctttgactt gatagaagaa
    22201 aaatatatgg ataaaattac attaaaagaa cttgctagtc gtgtgaactt gagtgcacat
    22261 cacttttgta gaacatttaa gcaaataaca ggtaagacta caatcgattt tataaatgga
    22321 atcaggcttg ataaagctat atattattta aaggaaacag atttaaatat gacagaaatt
    22381 gctatgagat gtggctttga tagcataaat tattttagtc gcttatttaa aaggaattat
    22441 aatatatctc caactaagta tagaaatgaa catagagaag ttagtaatgt tattttaaaa
    22501 gaagatatga aataattcat aaatatactt tatagaaaat atatattttt aaatctttga
    22561 gtttttctta ataaatatta ataaagtata gtacataaat gagtaagact acttgtatag
    22621 ttaaatgtga aaatgagtat gaaagaatgt agtgtctatg aaaagtatat tttaatatga
    22681 aactaaaatt ggaaaaataa gaatagcaga aaaaatgatt atattataaa tcagtttttt
    22741 tgagacatct ggcttagatt ctgaaagata tttaatcaaa gaaataaaac tatcaaataa
    22801 gcaagtaaac agctaaaata gtatgatttt tatagaaaat ttaaatccat cctaaagaat
    22861 taaaagaaag tcaaataaat ataaaaaaat tatatattta taaaaaattt tataataaaa
    22921 atcatcctga aaaatatata aaaatagaaa aaacatacaa gattctacaa taatagattt
    22981 ttttgttatt attacgagtt ttttattgca actgtagaat aaaagtatta ttatataatt
    23041 aagataatta tctagggaaa ttttggataa tcaaaatata ttttataaaa tcaaaataca
    23101 attacataaa ctttattaaa aatttgttgg gaatttctga ctagcattaa gaacgtaagt
    23161 ttgttggggg atggtatatg tggaaaagtc aaacactact gttacaaaaa aagaaaaaat
    23221 tgaagatata ggaatgaaat tagaacattt attgagtgaa gatattactt tttatgaatt
    23281 attacttgag attttgtata aagaaaaaga agagaattaa ttctcttctt taaggaatct
    23341 ttttaaatag gcattatcaa tcattttttc tatagcttct ctatcttctt tttcaagaga
    23401 atatattttt tctaagagct tttttgtttt ttcacttact gataagttct ctatgattaa
    23461 tttatcttct ttgcttattt ttgtattatc atttacgcct aataaataat ctgttgatgt
    23521 ttctaatgct tttgctaatc taactattat ttcactttta ggttctctta aattattttc
    23581 ataacgtgac aagctagcct cagttatacc gactttagta gcaagttctt tttgatttat
    23641 atctaattct tttcgtagat ttgctattct atctcctaaa ctttccatat gtacatcact
    23701 ccttaccgaa attataagtt attttgataa aaagtaaaat aaaattacca aaaatataaa
    23761 aaaaaagggt taaaataata aaatatattg aaaattacca tttgtatatg tataatatga
    23821 attatacaaa tggtaatttg atgagaggtg gtatgttgaa ataagaaact gaattaatta
    23881 ataaatatat agaaagtttt gaaaaccctt aattgagata taaacaatat gtacaaaatt
    23941 ttttgcaagt aaaattacca aatgtataaa ataaatcagt agcatagata attttatgct
    24001 ttaatacatt agattattta atttagttat aatggtcaaa aatgcaatct acaaataaaa
    24061 caaagtatta tcaaaaaagt attctttaag agaatttttt attagagatg taatttatat
    24121 aaataatcgt attaaaaaat aaaatactaa gtttaaaaat ttaaataatc tataaatcaa
    24181 ttataaaata ttatttctta gaaattaaaa tgaattaagt aaatggagga attgatatga
    24241 taataattag aagtcaagat aaaactaatt taatgcagat aaaccaaatt aaaatagatg
    24301 gtagtcaagt ttatgcagta tttgaaagta aaattgatac tgtaaaaata ggagattatg
    24361 aaaataatac aagagctata caagtgttgg acaatataca aaacttcatt gaaaatggaa
    24421 caaaatatga ttatataaca tcaaataaag tcagatacaa tgttaataaa atatttcaga
    24481 tgccagctaa atagtgagtg tgcattttag tttaataact aaagcccact ttcttttgta
    24541 gtatgaaaga gggctttaca tatttgtaaa tatcgaagta cacttgtttt atcaataaat
    24601 tatttaataa ggtataatgg accaattaaa caataaaaat tctcctaaaa cagcaagtat
    24661 taaatatata atagcttcat ttttgtaaag agaggtaatt tttttgctta tgtcatcatc
    24721 aattgtaata gcaatttcat cttgaataat atttttatat atagatggga aaatatcttt
    24781 tttctttata agattaaata aattatttac acctacccat ataaaatatc ctaaaacagc
    24841 acctaatgtg ttcatcatta aatcatcaat atctgtagct cttaagttaa acaattgaca
    24901 aagttcaatt gctaatgaaa aacctaatcc agttaatgaa acattgataa tatttctaaa
    24961 atttttccaa attaaaggta gtaaaaatcc taaaggcata aacataatta tatttaaaat
    25021 atatgttaag atgccaactg agtcaaaagg tattagattt atttcatcaa ttctaaaaag
    25081 cccactatac cttcctatat cccatatgct accaattcca gctttactaa gtgctagata
    25141 gatatataat aaaaaaatat atacccatac taaatgtatc attacattct tttcaacttt
    25201 caaatttttt cgttttataa cgactatttg gtatattaag catggtaata taacgcaaat
    25261 aaatgaataa aatgtccata tcattttatt ttgtcccctt tcaaatttat gtttttagtt
    25321 ttataagtac tatctttata ttaaactgta agttttaaaa atcttttaat aaaatcttaa
    25381 aaatttatta atttataaaa atatattatt aagattaaaa aatatatata atcaaagttt
    25441 ctacaattat atagttaggt atataaaaat tttatcgtat gtataaatat tataaatata
    25501 tggaaataat aatagtatat tttggtaaag taggaggaat tttatgaaat ggattaaatg
    25561 gtatagtatt acatgcatat gtatttttat agtagtagct ttttatatgt ttatatttcc
    25621 taataaaata gaaactattg atacttcatc tgcatatagc tttgttgaaa agaaagtacc
    25681 aaatagtgct gtatatcaag gatacaaaaa gaatccagtt gatggtacta ctacaattta
    25741 ttacagctat gataattcaa ctcatatagt tagattatca catccagaag actattcaag
    25801 gaagattaat tgggataaag tttcaaacat cagatttgat taatctttaa tatttataaa
    25861 agtctatata tctaaggcaa atatattatt aatcttattc atagttgagc actttctatt
    25921 atagaagtgc ttcttctgat ttatatcata aaatattact caacaatttg taaaatatat
    25981 tagtttataa aatatattga aaagataata ttatataata cgattgtgta agatattgat
    26041 aaaaaatcgt aataaatttt cattagtata tgctaatatt tttttacaat tttcgtaatt
    26101 aattaataga aaaatatatt ataataatat tatgaaaatt taaaaaagta agaaagaggt
    26161 aatattatga gaagtgatat aaaaaaagga atagaaggag ctccaaagag agcgttaatg
    26221 tatggaatgg gtcttactaa agaagaaatt gaaagaccat taataggtat agtaaatgca
    26281 caaaatgagg tgattcctgg tcatctgcat cttgatgaaa tagcagaagc tgcaaaaaat
    26341 ggagtaagaa tgagtggtgg tttgccatta gaatttcctg ctataggggt atgtgatggt
    26401 atagctatgg ggcatgtcgg aatgaattat tccctggctt caagagaatt aatagcagat
    26461 tcaatagaag ctatggctat ggcacatggt tttgatgctt tggtacttat acctaattgt
    26521 gacaagatag tgccaggtat gttaatggct gctgcaagac ttaatatacc aagtattgtt
    26581 gtgagtggag ggcctatgct tccaggtaaa aaaaatggaa aagtatatga ttttaactct
    26641 gcaatggagg gtgttggagc atgtaaagat ggaacagtaa gtgaagaaga attagaagag
    26701 ttagccatga actcttgtcc tggatgtggt tcatgctctg gacttttcac agcaaatagc
    26761 atgaattgtt taacagaagc tttaggcatg ggtataccat ataatggtac tgctgcgtca
    26821 cattctggag aaagaaaaag aatagcaaaa tatgcaggta tgtatgttat ggagttactt
    26881 aagaacgaca taaaacctag agatatttta acaatagatg cttttaaaaa tgctatagct
    26941 gttgatatgg caatggctgg ttctacaaat acagtacttc acttacctgc aatagcttat
    27001 gaatcaggaa tagagtttaa cttagatttt tttgatgaaa taagtgaaaa aactccttgt
    27061 ttaacaaaat taagtccaag tggaaaacat catattgaag atttacatat ggcaggagga
    27121 ataccagcta taatgaacga actttcaaag ataaatggaa taaatttaga ttgcaaaacc
    27181 gtaacaggca agactatagg ggaaaatata agaaattgtg aaatagaaaa tgaagaagta
    27241 atacatacat taaagaatcc atatagtaac caaggtgggc ttgcaatatt gaaaggaaat
    27301 cttgctctaa atggagctgt tgtaaaaaag tcagcagttg cagaagaaat gttagttcat
    27361 gaaggaccag caagagtttt taattcagaa gaagaagctg taaatgctat ttttggtaaa
    27421 aaaataaaca aaggtgatgt tatagttata agatatgaag gtccaaaggg tggtccagga
    27481 atgaaagaaa tgctatctcc tacatcagca gttgcaggaa tgggacttga taagcatgta
    27541 gcacttctta ctgatggtcg tttttcagga gcaactagag gagcatctat aggccatatt
    27601 tctccagaag ctatggaagg tggtttaatc ggactagttg aagaaggaga tataatttct
    27661 ataaacatac cagacaaaaa attagagtta aaagtagatg aagttgaaat agaaaataga
    27721 aaattaaaat ttaaaccttt agaaccgaaa ataaagcatg gatacttaag tagatatgct
    27781 aaattggtaa catcagcaaa tacaggagca gttttaaaat agtgaactat atttacgaaa
    27841 attagaaaaa attaagaaaa tattaattgg atatcttagg tgttatagca ctaatgaggt
    27901 atccttttta ttttgtatga aaaatatact gtttgtatac aaaaatatta aagatatttt
    27961 agtaagtttt gtatataagc aaacatgtat tttttaatat agttatctaa atattatttt
    28021 atatacaaaa aaatatgact cctaaaaata aaaaatatat cataaatata aataagtaga
    28081 tataggtttt aatttgattt ataaacctat tataaaataa aattcatgat ttttataagc
    28141 aataaaattt ttaggaggat atatgatgaa taaaagaatg aaactaattc cgtatgaaat
    28201 aaatgaaaat ctaagaggtg caaaaaataa attcccatat ggaataaaac aaatgaatgc
    28261 taggggaatg tgggatgaag gttatactgg taaaaatatt gtagttggta taatagatac
    28321 aggttgtgat atatctcatc ctcttttaaa aggaaaaata attggtggtg caaattttag
    28381 tgatgacagt aatggaaata aaaatatata tgaggatttt aatggccatg gaactcatgt
    28441 ggcgggtatt atagctgcat ctaactataa taatgaagtt atgggagtag ctccagattg
    28501 taaattatta atagcaaaag cattaaataa agatggtacc ggaacatatc aaagtataat
    28561 taatgctatt aactttgctg taaataacaa ggttgatatt atatctatgt ctcttggggg
    28621 aaacaaagat gataagaatt taaaaaatgc tgtcatgcaa gcagtaaaaa ataatatttc
    28681 tgtagtgtgt gcagcaggta ataatggaga tggtgattct agtacaagtg agtatagtta
    28741 tccagccagt tatgctgagg taatagaagt aggtgcaata aatgaaaact atttggttga
    28801 aaagtttagt aattcaaata ctacaataga tttggtggct ccaggaagaa atattatatc
    28861 gacttatatg gataataaac ttgctattat gagtggtact agtatgagtg caccatacgt
    28921 atcaggctca ttagcactaa ttaaagaatg ggcaagagag gagtttgaaa gagatttaga
    28981 tgaagctgaa ctgtatgcac aattaataaa atgtacgaga gcgcttggaa tacctagaac
    29041 ggaacaagga aatggatact tatatttaaa tctttataaa tacaagaata atagcaaaag
    29101 ataatttttg atttgatgat aaaatagcta tattatatag agtcgagaca aataataaaa
    29161 attacttagg tgtaagattt tacatcaatg tataaaggta ttaagtgata aaatttataa
    29221 acatattagc tagttagaat tgaaaaataa atatacgata ttatagatag cacatctgga
    29281 aaaggtgtgt ttttctatgt acttatacat ataaaagatt tataagagat gcaaaagtac
    29341 tataagttag aaatttttct atgaaagatt agaaatacga tacagtgttt tgatattata
    29401 aaatgaatat aaaatataaa tgataaatat tatcaataaa tattgaattt caaaatcaat
    29461 tgtgatattc tatatttaga aaaataaaga gatttcagat aaagaaatct tttgtttttt
    29521 agatgttagt tagctataac taactattga ttaattaaaa aatactacag gaggtaaaaa
    29581 tgagtaaaat atatattgtt tattggagtg gaacaggaaa tactgaaaaa atggcaaatt
    29641 ttgtggctga aggtgtgaag ttaaaaggta agacaccaga agttttagat gtgagcttac
    29701 tgaaaccaag tgatttaaaa gaagaagata aatttgcatt aggttgccca tctatgggag
    29761 cagagcaact agaagagggg tatatggagc catttgtttc agaattagaa tctatggtat
    29821 caggtaaaca gattggatta tttggttcat atggatgggg aaattgtgaa tggatgagag
    29881 actgggaaga acgtatgcaa aatgctggtg ctacaattat tggtggagaa ggaattacag
    29941 caatggaaga cccaaatgaa gaagcaaaag atgagtgtat agaattaggc aaaacgttag
    30001 ctgaataaat ttgtatatta taaaaatagt ataaatagca actaatgatg atagcagtat
    30061 ataataataa gagagactaa tattatgata cataagaaaa tatccttaat agagatagat
    30121 aaaatattag tctcttttaa tataaaatta gatttataat ttaatgttgt ttttgaattg
    30181 gtacaatctc attataaaaa gataataatt gattgataac ataagtgata aaggtagtat
    30241 cttgtgcaaa acaaagcata tttgctccaa tattaaccca ttcttcaata cttttctttt
    30301 ctattgtagg aaaaataata aagggcatct tatatttttt gcatatttca gcagcatgag
    30361 aaatcatatc ttttatttca attctattca tatatccgga aaaacccatg tctaaagata
    30421 agtcaccagg gcctaatgct ataatatcaa taccctcgac ttttactatt tcttcaagat
    30481 tatcataacc tgctttctgt tcaattaaca tcatttttaa tgtttcattg tttgcgtttt
    30541 tgacatagtc aaaataattc atattcccat aataagaggc tctttgagga ttatatcctc
    30601 ttataccgtt tggaggataa gtacaagctg ctacggcttt ttgtgcatct tctactgtat
    30661 taataaatgg gaaacaaata atatctgttc ccatatccat tatgggctta acaaggtcag
    30721 ggtcactgtt tactaatcgt accaaagaag cagcaccacc agcatgggca gctatcatat
    30781 gttgctgaat gtctttacgg tctaaagcac tatgttctcc ttcaatccaa ataaaatcat
    30841 atccagatat accgattaac tcacttacaa ctgaatcaga cagtgaaaca gctactccac
    30901 ataagacctt tccttcattt agcttttctt taatcatagt tgcatatttt tccatttata
    30961 tcatcctttc ttttgtaagt tttcttttac acttcaaaga gtacaacttc aacctaactt
    31021 gaagtcaata cttttttgtt gactactgta taaggtattt ttataatatt cttattcata
    31081 taaaatttag ggaggtagag attatgaaat attctataac tgatgtatca aaaataacaa
    31141 aaatttcttc atctgctatt cgattttatg aagaaaaagg tttattactt cctatcaata
    31201 gaaaaccaag tggtgttcgc tatttctctg aagaagatgt agagcgtcta atatttatca
    31261 aagaattaaa aaatactggt ttatctatta aagatatcca tgaatgcttt catttttgtg
    31321 atatgggaga tggtacaata gataaaagaa tccaattatt tcaacaacat aagcaaaaca
    31381 ttaaaaataa aatacatgaa ctagaaagtt gtatggataa aatagatgag aaaatatatt
    31441 acttaaaaga aaaaaagatg tgtaaaaaat aatccttata gaataaagaa ataatttttt
    31501 gatttttcta atataaagag taaattcaat tggaaacatt tgaggaaaga ttttttacac
    31561 tatattttta ggaagaattg gacaatgttc tatataacta tttatctata caataaaaaa
    31621 gaaaattatg ataatgtata ttataaggag atatttaaag gaataaaaaa atatttagat
    31681 aaaaactacg aggtgagttt atggtggatt ttattgagtc aaataatgaa gtacaaaaat
    31741 ttgattgggg agaggttatg tggatacacg aaccatcaaa aacacaattc aatagactta
    31801 gtgctggaat tgtaagattt tttccgggaa actgccaaga aaagcatttt catttaagtg
    31861 aagaacagct tttatatgtg attcagggag aaggaataca aatgattgat ggtaaaaagg
    31921 tcaatataaa ggaaacatct atagtttatt gcccaccata ttcagaacat gaaattataa
    31981 acactggtaa aattgattta gtaatattaa ttacttatgt tcctcataaa ttttcgagtt
    32041 tgagacaaat acctatagta ttttctgaaa acaatataca agagttagtt aatgtaaaca
    32101 taattgaaaa tcttgcaaat caaatatcta atatattgaa gcttagaata tctgtatatg
    32161 acttaaagta taaaggaata tttgagacta agaaagaaaa taaattttgc gatatttgta
    32221 aaaatataaa accgtgtact aaaaaacttg ttaaaagcat aaataatgat aactttgaaa
    32281 aagtgtacca ttgtgagtat ggtgtttcca gtttagagat acctatagta ttagaagaaa
    32341 atatagttgg atatatagaa tgtggtaatt ttatagtata taagtctatt gatatagata
    32401 aaaatttatc tgaattatca agtagttctg gtattgatat aaaatacata aacaaaattt
    32461 acaatgaatt tccattaaat cctaaaagta gattatatgt attaaaagaa aatttattaa
    32521 tgatgtctga atttattcag gaaatagcta agaggaattt ttttgaaaat caacttagta
    32581 taaaagatga ggagatatta aagagtagaa aagaaaatat aagacttgaa gaggcactta
    32641 aaaaagcaaa tagtagatta ttagaagaag agtatattat taatccgata gatatgttca
    32701 ataattcttc aaaagaatat ccctttgaat tagaacttta tattgaaaaa gaaattaaaa
    32761 atatgaattt agaaggtgtt tataatctaa tagatacaaa caaattaaga tataatgatg
    32821 ttagagatac tattcaggaa atgatatttg tattgtctag aacagtgctt agagatttag
    32881 aggatttaaa acttatatct tatttaagaa ataaatataa taaaaaaata tcacttgtag
    32941 acagtgatga agatttatgg aatgtattat ttgaattttc caaagagtgt attgataaga
    33001 atagagcatt ttggagaaaa gataaaggaa atctaattga aaatataaac gaatatataa
    33061 aaaaatatta taaagaaaat ataaatttga atagtatatc agatgttttt tttataagtc
    33121 caaattattt gagttctatt tttaatgaaa gaaataaagt ttcaataact gagtatataa
    33181 atcttcttag gatagaagaa tctaaaaaat atctgttaga tagaagcatg agtattagtg
    33241 atatttgtaa gaaagtaggt tttaataaca gtagttattt ttcacaaata tttaagaagt
    33301 ttaatagtat aactccaaat gaatatagaa agaatatgct ggataataag tattaaataa
    33361 gattatataa tatatattgt aagaaaaatt gaaagagaat gatggaggaa ttttatgttt
    33421 tcagttattt ttttatgtat aggggggttt ttagctgctt ttgtagattc tatagcagga
    33481 ggaggaggga cttataagca tgcctgttct tatggcaatt ggagtgccag tacatcttgc
    33541 cattggtaca aataaatttg cagcatcagc aggatgtata agtagtgcct atagatatgc
    33601 aaagtctgga aaaattaata acgatctttt aaaaaaatta gtaccattta ctattattgg
    33661 tagtgttcta ggtgtgagat gtgtattatc aataagtgaa gagatattaa atgttttggt
    33721 tgtggttatg attttaatag tggctattta cacctttatt tctaaaaatt taggtcaaga
    33781 agataatttt gaagctgtta ataagaaaaa tttaagacta gggatgctta tggctcttat
    33841 aatgggtttt tatgatggtt tttttggtcc aggtacagga acttttttga cttttggatt
    33901 tataaaaata tatggatatg attttttaca tgcttctgca aatacaaaaa tattaaactt
    33961 aacaagtaat ataacttcat tgttattatt catgataaat ggtcaagtag attataaaat
    34021 tgctatagtg tttgcattag tgatgataat gggagcttat gtaggtgcta aagttgctat
    34081 aaagaaaggt tcaaagatga taaaaccaat atttttagta atggcattat ttatggtcgt
    34141 aaaattggta tatcaaacat tagtttagtt tatagacttt ttaaatttat aagtaattgt
    34201 aaagctttta tatttaatct aatcatatag ctttataaaa attctaatta tcttctaata
    34261 tagttcatat ataatacaca tataaattgt aatattacaa tagaaggatt atatatcata
    34321 aaaatataac cttgatttat atatatgaaa tatatggtaa tttgtaggag gaatgtttat
    34381 gaacatatca agaagagcta tgaagataat tgaactggca caaaaaattg ctaataaaag
    34441 aggtgtaaca gtacaagacg cttggaatga tgcgatgaaa gaatataaag aaaaatatga
    34501 atatgttgca taagatatgc gttatatttt aaatataaga aaatataaaa caaaaaagat
    34561 tgtctcaaaa taagattgta ttgagactca aaagttagat tttatacagg aatggaattt
    34621 tcattcctgt atttttaatt ttacataact ttaaattcat attcaaatct atatttaaca
    34681 aggttatgct aaattaattt ttttaattct tttgttatta taataataaa tatattctat
    34741 tatagttgta tctaattagt agaggttttt atgcattttt atacagtata tttcttattt
    34801 cattcttttc tatttaaata ggacttaact actttttaaa ttg
//
LOCUS       DAEQJM010000039        34111 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.039, whole genome shotgun sequence.
ACCESSION   DAEQJM010000039 DAEQJM010000000
VERSION     DAEQJM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34111
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.039"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(602..1195)
                     /locus_tag="KRQ43_002278"
     CDS             complement(602..1195)
                     /locus_tag="KRQ43_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH2742630.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            2043..2693
                     /locus_tag="KRQ43_002279"
     CDS             2043..2693
                     /locus_tag="KRQ43_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH2742631.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRMYFNRKNRIVTK"
     gene            2907..3578
                     /locus_tag="KRQ43_002280"
     CDS             2907..3578
                     /locus_tag="KRQ43_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742632.1"
                     /translation="MAKILVVEDEKRMQSIIVEYMQKGGYTCITANDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            3575..4705
                     /locus_tag="KRQ43_002281"
     CDS             3575..4705
                     /locus_tag="KRQ43_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2742633.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDAISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLIINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRIIEQDEISKIWSKFYRSVQSQ
                     RKGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            5110..5955
                     /locus_tag="KRQ43_002282"
     CDS             5110..5955
                     /locus_tag="KRQ43_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742634.1"
                     /translation="MIKVGELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSLFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            5955..6983
                     /locus_tag="KRQ43_002283"
     CDS             5955..6983
                     /locus_tag="KRQ43_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742635.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNIGFFEGVKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            6986..7999
                     /locus_tag="KRQ43_002284"
     CDS             6986..7999
                     /locus_tag="KRQ43_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742636.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTML
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGAPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILVVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(8481..9731)
                     /gene="cme"
                     /locus_tag="KRQ43_002285"
     CDS             complement(8481..9731)
                     /gene="cme"
                     /locus_tag="KRQ43_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBH2742637.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHNIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLVMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIVAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(9817..10563)
                     /locus_tag="KRQ43_002286"
     CDS             complement(9817..10563)
                     /locus_tag="KRQ43_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2742638.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(10678..11700)
                     /locus_tag="KRQ43_002287"
     CDS             complement(10678..11700)
                     /locus_tag="KRQ43_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBH2742639.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWICKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(11700..14120)
                     /locus_tag="KRQ43_002288"
     CDS             complement(11700..14120)
                     /locus_tag="KRQ43_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH2742640.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLALLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKILINQGNLNTFGTNLVNDILSKTRHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSDSEIGDEDDYAVIETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(14206..15126)
                     /locus_tag="KRQ43_002289"
     CDS             complement(14206..15126)
                     /locus_tag="KRQ43_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH2742641.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHFVDIYLPIEPF"
     gene            15736..16662
                     /locus_tag="KRQ43_002290"
     CDS             15736..16662
                     /locus_tag="KRQ43_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH2742642.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSENS
                     NAEIVTKNSDIFKNIEKYIDATINNNQKTMKYKHRDELFKNSNTNTYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENLDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(16850..17470)
                     /locus_tag="KRQ43_002291"
     CDS             complement(16850..17470)
                     /locus_tag="KRQ43_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742643.1"
                     /translation="MVLINILLVDDHMLFAKSLSIALEEYEEIEQFYSTQDIHNLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGVTCFPSENTEVIIEDLTNMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(17442..19025)
                     /locus_tag="KRQ43_002292"
     CDS             complement(17442..19025)
                     /locus_tag="KRQ43_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2742644.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTETYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLALDSWYLLLSFVTTPIGTIIFKILSTVIVYVS
                     IKFIFLFLFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFL
                     YIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPEVQDIIYETLNNLNTCIRNQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNINDNGVKNTSFKTPLDITKITFDIIKHKGIISIKEQVENLGGTISISDNIPHGV
                     CVQITIPMKGDGSYKYFVS"
     gene            complement(19169..21196)
                     /locus_tag="KRQ43_002293"
     CDS             complement(19169..21196)
                     /locus_tag="KRQ43_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH2742645.1"
                     /translation="MNIFYMAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENVLICSGAFITGLVLGALSHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAISNGKFLYKTSLVKLIRHEKSAEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQKSKKNKRTFYTDMK
                     IIAIPNFIYRIRSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLINGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTSILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYDNIQIKKIIKKQVLPFFNIPFLLGILDCIFAT
                     LVYKTALMQNLLGNSFSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKN"
     gene            complement(21209..21958)
                     /locus_tag="KRQ43_002294"
     CDS             complement(21209..21958)
                     /locus_tag="KRQ43_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742646.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFDIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYAASFANRILIFKDG
                     HIIKELNKQPNNRHTFYELIIQEIAKLDTKR"
     gene            complement(22255..23907)
                     /locus_tag="KRQ43_002295"
     CDS             complement(22255..23907)
                     /locus_tag="KRQ43_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HBH2742647.1"
                     /translation="MNNKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYKMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSDILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKIEYEITINAITGKILEFEIDD"
     gene            24506..25627
                     /locus_tag="KRQ43_002296"
     CDS             24506..25627
                     /locus_tag="KRQ43_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH2742648.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            25663..26076
                     /locus_tag="KRQ43_002297"
     CDS             25663..26076
                     /locus_tag="KRQ43_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2742649.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            26069..26608
                     /locus_tag="KRQ43_002298"
     CDS             26069..26608
                     /locus_tag="KRQ43_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH2742650.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEASCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVAAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(26808..27293)
                     /locus_tag="KRQ43_002299"
     CDS             complement(26808..27293)
                     /locus_tag="KRQ43_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742651.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFDLDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            28144..28521
                     /locus_tag="KRQ43_002300"
     CDS             28144..28521
                     /locus_tag="KRQ43_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH2742652.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            28929..30734
                     /locus_tag="KRQ43_002301"
     CDS             28929..30734
                     /locus_tag="KRQ43_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2742653.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIYKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNVCKNKDINIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            30811..31350
                     /locus_tag="KRQ43_002302"
     CDS             30811..31350
                     /locus_tag="KRQ43_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="HBH2742654.1"
                     /translation="MQYAIELYYDKKTEKQLFDLSKKIADEKISTKYLEWKTRPHLTL
                     ACFNDVDEACCIDKLKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPIMNSSMYQFQREL
                     YEVLQDFDSNGWEWYHPNRWVPHCTIALTGDDESEAFFRASDVLLREFKKISGEFVSI
                     GLVKITFPVEEIFTVNMNR"
     gene            31973..33187
                     /gene="dpaL"
                     /locus_tag="KRQ43_002303"
     CDS             31973..33187
                     /gene="dpaL"
                     /locus_tag="KRQ43_002303"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH2742655.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLRDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            33520..>34111
                     /locus_tag="KRQ43_002304"
     CDS             33520..>34111
                     /locus_tag="KRQ43_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH2742656.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT        12583 a         4243 c         5298 g        11987 t
ORIGIN      
        1 ctaatttagg aagtatagaa aattaatcta aagaagtata ataaactaat ttaagaaata
       61 tagaaaatta atttaaagaa atacaataca ttaattttta agtaacatta aattaatgta
      121 agtaaaataa tgttcatatg aagatttaaa ggtgcatttt ctgaagctaa gtatatgtta
      181 tgtctctata tccggtgaag tttaatagct caagaaaatg cactatttat gatgattatt
      241 ttgttttatt tccaattttg gaaataacta ttctaattaa atctaaaatt ataccataaa
      301 taagaaaaga aagtatagat gctatgtacc aataaatcga aattgaccct gtaattgttc
      361 tacatgggat ttgcatgcct gaatccataa aaacaaaaaa actatcaatg gtagaaataa
      421 tagacaaaat aggatttaat cctattagaa taatactttt tgagtcttga ccaatttggt
      481 ggatataaat ctcaaataat gcaattaaaa aaaacaaaat gtaaaagatt taataatttt
      541 tttcatcaaa atacctcacc taatataaat tctgtttgca ctatttgctt actataacta
      601 tttatctcca ttcagtcaca tcacttaatt gtaatctagg tcttcttgat ggttcttcgt
      661 caggataacc taaagatatt gctgccacta attgactatc tgtatttaac cattcacata
      721 attcacgata tgcaaagtat acatcacaaa tccaaagact acctagacct aattccacag
      781 ctgtaagcga catattctga attgcagctc caattgattg catgtttgcc atttcataga
      841 atcgttcttc aggggatagc ttttctaaag gtgatttacc taatatattt aaaataaaaa
      901 ttgttactgg agcttgtttc atgatttcaa ctgtgtaatt tgcaccagcg atatgttgac
      961 gacttcctgg aagaagccca ttatcattaa tttcattttg aatacctttg ctcatggctt
     1021 taagcataga ttctttttcc ttttcagtga tgacaacaaa acgccatggt tgcctgtttt
     1081 tagatgaagg tgcatttatt ccagcttcaa ttattttctc tatagtttca tgtgaaatgc
     1141 tttgattttt atattttctg atacttcgtc tttttgatat agaatcactt atcattttaa
     1201 gtaacctccg tttatttttt ggaaaaatct atttattttc tatttttaat tattttagca
     1261 ttaatcagaa aaaaagtcat tgattttagt atacaattat taacgattat attaaggatt
     1321 gtatcaaaaa gtatgtgatt atactaaggg attatattag acattatatt taaaattgta
     1381 tgaaaggttg tatttaatat tatattaaga gagatatata ttaggattta tatatattaa
     1441 gatttattat attgagccct tatattaaat taaggattat aatttaaaaa taagctataa
     1501 aaacccaata ttgttttgtt cagagataaa aaagaatact ttaggtgatt tttattaaaa
     1561 attaagagtg ataagattat atactttata aatgtaaata tgacgaataa aaatgataaa
     1621 tataataatc tatatattta cattaggagt tttctatact ataattattt atatttaaaa
     1681 ctaaatataa atgttggaat tatttaggat ttgaaattgt ctaaagataa atataagtga
     1741 tgaagaggtg atgtgatgag attagatatg gatagtatgt tatatgtact aatttatatg
     1801 acattattgg tatctatcat tggaagtata ttttattttt gtaaagacct cttaaatcat
     1861 aaaattaagt atgttttaat aagagacata tttgtaaata gaattacata ttctgaagaa
     1921 cggttgccta aacagtatat agtttttcag aaatatgata tttggaggta ttgtagtttg
     1981 ttttaatttg aaatgaatct attataaatt ctaaagttta aaaataaaaa ggagagaata
     2041 aaatggattt catttcaagt atattgcaag gattattaag tatattattt aattttacag
     2101 gtgattttgg aatttctatt gtacttataa ctttaatagt taaattagta cttatgccac
     2161 tatcattaaa acaaagattt tctgtaaaaa aacagcaaga attagctgaa aaaatggaac
     2221 atataaaaga aaagtataag aatgatacta aagaattgga aaagcaaata caagtaagtt
     2281 ctgtagaaag tatgaagagt atgctgggat gtcttatagt tttggttcaa atgccagtag
     2341 tatatgcttt atatcatgta tgtttagata tgacaaagga atttacaaca attataattc
     2401 catggattgc taatttaggt acatttgata atttgtttat attaccttgt atatatacat
     2461 taattatgtt agcttcaaat ttagtgaatt atataccata tttaaaaata aattctcaag
     2521 taaagtttaa caaacaaatg gctgtggtga ctaccataac aagtcttata ctaactgtta
     2581 gaactccagt agccataggt ctgtacttta taacaagtgc aatttattca ttaattgaag
     2641 atatttgttt tagaatgtat tttaatcgaa aaaatagaat agtgacaaaa taatataatt
     2701 attattagaa atattttagc ctgctaacat agaaaaagtt agtaggctat ttttatctat
     2761 gatatcaatt ccattaagaa tagtctaaaa aatactatca aaatgctata aaaaatacta
     2821 taaaaatact ataaaaaaat agttgaaaaa taaataaatt aatataaact aaaataaagc
     2881 ctacaaaaaa gaggtgataa atagaaatgg ctaaaatact agttgtagaa gatgaaaaaa
     2941 ggatgcaaag tattattgta gaatatatgc aaaagggagg atatacttgt ataactgcta
     3001 atgatggagt cgaggcactt acaatattaa agagcaacaa tatagattta atgatattgg
     3061 atattatgat gccgtattta gatggatttt cagtgtgtag agtttcacgt gaaatgacta
     3121 atatacctat tatcatattg acagctaaag gtgaagagga ggacaaatta aagggttatg
     3181 aatatggcgc agatgattat ataacaaaac catttagccc aaaagtactt ttagcaaaag
     3241 ttaatgcctt gttacgtaga tacactactg atattcccaa aaattcattg agtttaggaa
     3301 agatttttat tatggtagca tcaaggcaag tgtatgtaga agataaattg attgatttaa
     3361 catataaaga atttgaatta ttgcgtttat ttatggaaaa ccctaatcaa gttttttcca
     3421 gagagaagct tttaaattgt atatggggat atgattttga aggaaacaca cgaactgtag
     3481 atacacatat aaaaacctta cgcaaaaagc ttggtagtga aggacaccat atagttacat
     3541 taattcgttc aggatataag tttgaggtta aggaatgaat agtttaagaa agattataga
     3601 aaaactgaaa aatgtagata tttcaaattg gattaaacaa aattttggac tatattcagt
     3661 tagaaaaaaa gtgtttttac tttctaaatt atcaggagcg ttaattatat tattttatct
     3721 ggttgttgaa gaattttcga taaactctaa atttgaattt tggatttggt ttataatact
     3781 ggttatattt attatgagta ttgatttttt attgggaaaa tttatttcag aaccaatcac
     3841 atctataaat aaatctgcaa aaagtatgtc ccaacttgat ttttctaatc catgtactgt
     3901 aaatactaat gatgaatttg gagaactttc taggagcctg aatacaatgt ctacaaatct
     3961 acaacaggca ttatcagacc tagaaagtgc aaatattcaa cttgaaaagg atgtaaataa
     4021 ggaaagaatg ctattggaac aaagaaagga gttggtagat gcaatttcac atgaaatgaa
     4081 gactccactt ggcattatac gtgcgtatac agaggggctt atggatgaag ttgatgaaga
     4141 aaaaaagaaa aattatatga atgttataat agaagaaact gatagaatga acaatatgat
     4201 tgtatcatta ttagacttat ctgcattgga agcaggagtt tctaaactta acccagagcg
     4261 ttttgatttt atagagtttg ttgaaactgt ggcaggtcgt cttttaattg atataccaga
     4321 tgccaatttt tattttacat atgatttgcc agagtatgaa gtttttgtag tggcagataa
     4381 aatgagaatg gaacaagtag tagagaatct aattattaat gcaaagaagc atgttgtata
     4441 taatggtaat ttagatttat cgattacatg tgaaaatggc ttgcttttat ttgaaattta
     4501 taatgatggt aggattatag agcaagatga gatttcaaag atttggtcta agttttatcg
     4561 tagtgttcaa tctcagcgta aaggaggttc aggtctaggg cttgcaattg tttcacaaat
     4621 acttacaatg caagggttag aatatggagt gaataatcgt gatagaggag tagagtttta
     4681 ttttatgatt ccaattgatg aataatttag tattaattta taaattataa gtatctgatg
     4741 taaaatattt ttctttgtat acgtaagtat ttaaagagaa taaaataaaa aacttaatga
     4801 aaaagtctaa taaaaagttt aatgaaaagt cttgttttcc tgatgaaaac aagatttttt
     4861 attaagcttt ttattatttc acttcgattt cacaagagag acactctgat ttcaccaaat
     4921 agaaataaaa taggttaaat aaattaaaaa atagaagcgt aattaaataa ggttacaagg
     4981 gggagtactt atgaaatggt atacatggtt gactattata ttgataatat tgctttctat
     5041 tccgcttaaa attaaattta taaaatggtg ggatagacga caaaaaaatg ataaaggagg
     5101 ttatgataga tgataaaagt aggagagtta aaattttctt atggaaaaga taaacagata
     5161 ttgcatggac ttaattttga agtaaaagaa ggagaaatct ttggattcct tggacctaat
     5221 ggttcaggaa aatccacaac acagaaaatc ttaaatggcg ttttaaaagg ttacaatggg
     5281 cacgtatccc tttttgggaa ggaagttaaa gcatatacag agtctctata tcaaaagatt
     5341 ggtgttttat ttgaatttcc ttatttatat accaatttaa gtgcaattga taatttagaa
     5401 tatttttcgt ctttttatcc taaaaatcaa aggagagaca tatatgaact cttagatttg
     5461 ttagagttta agaaagagtt tataaataag cctgtatcat cctactcaaa aggtatgaag
     5521 caacgtatta gcatggcaag agcattggta agtaatccaa agttgttatt tttagatgag
     5581 cctactagtg gacttgaccc atctggagct gtactatttc gtaagattat tgaagaagaa
     5641 cgaaaaaaag gaacaactat ctttttgact actcataata tgctagatgc agatttaatg
     5701 tgtaacaatg tggcttttat tgcagatggc aagattatgg taatagataa acccaaaaat
     5761 ttaaaaatga aaaatagcaa taataaagtt gaagtggaat ttgtatataa tggaaatcga
     5821 gatattgaaa ttgtagatat acaagagtta gaatctggaa taacttttaa atatgatgaa
     5881 atcttaagtg tacattcaaa agaacctaca ctagaagaag tttttattaa atacacagga
     5941 aggatgttag tgtaatgtat tctaaatttt ttaccttagt aaaaaaagat ttttggatga
     6001 tgatttatgg taaatttttt gtgctgacac ttggctctct catactttat tcgtgttata
     6061 ttaattttgg ttatgtaaag tttatggatg aagatagtta tcacaataat gtatatctat
     6121 ataatccaga gaatataagc atgagtgcat ctccattaat taatcaagtt tcttctatag
     6181 gtgaattaaa agcaaaactt gatgaagata caagtgcagt ttgtattgat atgagttcca
     6241 gtaagccgaa agtaatttta catgaaagta ttaaaggagt tgacaattat agagctgact
     6301 atgcattgtc attattatca tcagaaaaag accataatag caaaatatca gacaacaatg
     6361 caataattca aattaatgat aaggatacat ctgagataaa acaaagaaaa gacatgactt
     6421 gtgagatttt attctttgaa attgtagcta ttggattttt agggattgcc tctttattat
     6481 ttaaagaaaa gcagatggga gtaatgcgta ttactggtat tttacctgta aaaagaagtc
     6541 tttttatatt atcaaagata tttgcttttt tgatatgtga cctatgtttt acagttcttt
     6601 tagtagtatt taatattgga ttttttgaag gagtaaaaat acttccacaa gtattagttc
     6661 aagctagtat tttatcaatt attatgtctt tgattggaat aggatgctca atgttattga
     6721 gagattttaa gcaattttct cttatatatc ttgtggttgc tgtattcata actacaccta
     6781 tatttctatc tgcaaataca tcttttgaaa tagattggat taaatatcat cccttctatc
     6841 atgtttatag tcagcttaaa aatgcgtttt tcatgaattt ttcaaaagaa ttagtttatt
     6901 ttgtagtgtg ttctttgaca ataatagttc tatttttact tgtaaaatat atttttaata
     6961 aagagttggt tagggaggga taatcttgat aggattacgt taccagttaa agagtataaa
     7021 aaaagataaa atgtgtataa tttccttctt tttaccagtt gttatggcga ttttaataaa
     7081 ttttatggga acaattgata tatcttcatt aggagagata cgttttggta tagtgaagga
     7141 tacacttcct gtacaaacag agcagtggtt gaagaagtat ggtatggtaa gtgtatatga
     7201 cacaaaaatg catttaatac gtgaaattaa ggatattaaa acggacacaa ttggagttgt
     7261 tagagatggt aaaggaataa aaactatgct ttatggaaat gagattaatg ctataaaaaa
     7321 tgttggaaag acattgccag agatgtttag actaaagggt gatttaaaag atgttgaggt
     7381 tacaatattg cctaaagata gtattttaaa agagtttcag aatgttttta ttgctatgat
     7441 tttaattact gctatgttta tgggatgtac ctttaatgca atgaatatta tatctgaaaa
     7501 agaagatgga atatcattta taaatgaagt tttgccacag agtagaagtc agtatattat
     7561 acaaaaagta tttttgggtc ttttatgtgg gtgtttatct tcaatgataa ctgtatttat
     7621 atgtttggat atttcaatat tagatatgat aatgatgttg ttactcgttg tattttcagc
     7681 atttatttca tcacttatag gtttatttat tggaaagttg tcagaaggtc ttatggtagg
     7741 aattgtttat attaaaatag taatgatttt atttataggt gctcctttgt taatatatct
     7801 tctaggggtt aataccagcg gtatagggaa tttatgctat ataatgccat cagttgctac
     7861 atttaatggt attatggaga ttattaatgg taatgttatt attataaaag atattgtaat
     7921 tttggttgta cattgtgtag tatggtttat gatatatatt attttagata aaaaaagaaa
     7981 gttatctttt agtagataac tcagtataat tataattggg acaatttaat aggtgattta
     8041 atatactttg tatagtgtaa tttatgtagt gcaatttgta tactttaatt tatgtagtgt
     8101 aatagttagt tttattttat aattattcaa tataatttag taagaaattc agtacaatta
     8161 gagctactta gtggaaaact taataggtac ttaaactata taaatacttt attttcctcc
     8221 atttgtacta taaatttaat ttatgatata aatggaggta ttattatatg aggtattatt
     8281 atataaagtt aataaagata gtatcaaaat attatttgct ataaagagag ggactcaaaa
     8341 taaagataaa cctatttttc aatgttgaaa tgataaaata tatttgattt catataaaaa
     8401 attttcttca taaattaaaa agtccatttt aagccccctc atttttaacc agataaatcg
     8461 agttaaacta tttaaatata ttactcggat tcatttgact tagatattcc ttgcttgtaa
     8521 aattgttttg aataggggat agccaaagca aaaaataaaa gtataatccc tgctacgatt
     8581 attaaattat taatagaaat tacatctgcc attggtccga aaatcatcat accaagagga
     8641 ataaaaccag tatatataat aataggtaag ctaagaactc gacctagcat ttgtggtgct
     8701 acatgctctt gcaacatagt catagctgat gcttgaataa ttggaattga aaaattcgta
     8761 aaaaacataa atataaaaaa ttgccaagct tgtgttacaa gacctagaat aattgaaaaa
     8821 atagcatagg ataatattgc tagaaaaaag gtcttatttc tatttttaaa accaccaaaa
     8881 actcctataa tcaatccacc taaaaccata actaaaaatc caatcatttc aataatagac
     8941 aggtatatat aacccttgcc aaatgttcgt tcaataagaa gtcctataag aaatcctgat
     9001 ggaacacaaa gaagcatgaa tgctccataa gtgaaaagca cttttctaat gaacttatct
     9061 gaaaaacagt actttatccc tgataccata tctgcaaaaa atgagacttt ttcagtttgt
     9121 tttggtatat tatgtttagg aattttgatg aatatcaata atacaatagc aataattgca
     9181 gtaaatacat caattaaaag aacttgattt attttattac caaatccaag tattgcagca
     9241 gctacaatag gcactataaa ttgtactata gactgtagac tactatttat accattaaaa
     9301 cgcattaaat gttcttctgg tacaagttga ggaatcattg cgtttacagc aggtgtttgt
     9361 acaccacttc ctagtgaacg tataacagat attactgata tggctattaa ttcacttgtt
     9421 gtgccatttg atgacatcat aaatagaatt agaactaatg tagatatagc aattgttgaa
     9481 tctgatacaa ttatgagtac ctttcgattg tagtagtctg cccatacacc agcaaaaaaa
     9541 gaaattatca tttgaggtat aaaggagcat acagttaaaa ctgttaccca tacacctgat
     9601 gatgtctgaa gtgtgacata ccatatcatt gccatttgta caagtgatga gccaaataag
     9661 gaaatatatt gacttgctaa aaaaagaatg acttttttct tccatgtaga attagtattt
     9721 ttgttttcca tcctattcct cctttgattt gtgtgttgaa tttttcttgc tcttaaggat
     9781 aacacacaaa tcaaagtctg gagttagagt ggagggctag gaaaattgtt ttttcataat
     9841 ttgaagatga gatttcatgg tttttgcatt atgttcagct tctttcaatg aagttatcag
     9901 tttgtcacac actgagataa tttcgtcatc atcttttgga gtgtcaagga cagttttaat
     9961 attagtatta ggattagaag ataaagcatt taacattcgt aaaatagctg aaagagaata
    10021 gtttgcacaa cgaagtgcgc ttataatttt aagtcgtttt atatcttcat cagtatatac
    10081 acgataacca ttttgttttc tttttacttt taacaaacca ttcatttccc aatttcttaa
    10141 agtatctatt gtaacattta agtgttctgc agtttctttt ctagttaaaa agagtttatt
    10201 tgtttctgga gtatttccat ttaaaatctg tgcaacaata gtaagtgctt cctcggcatt
    10261 agatttttct atttctaatt gttgcaagta ttgatttaca agactaatag ccttatcaaa
    10321 gtccctattc gctgatgttc ttacaatctc aagggcatct tttcttaatc ccctttgtac
    10381 cacttcaatt ttcaaggctg tacgagcaaa tctaaattgt tctatatgaa aatcattaaa
    10441 gatacgataa ccattggtat tacgcttagg tttaggtatt aagtttagtt cttcatataa
    10501 acgtactgta ttaggatgta caccaattaa atctgctacc tctgatgtcg tgtaagtgtc
    10561 cattagtatt caactccttt tagatatata gtattagtca taataacacc aaacaaaagt
    10621 ctggtgttat agtggagggt ttggttatct aagagtaatt agtttatcta agagtgatta
    10681 atctattata gaagtaagta tatatttttc aataaactcc catctatcac gaggtttaaa
    10741 cactatttta gatggtatgg ctattactaa gtcatattgt ggaatacaac aaatagcatt
    10801 tcctccagtt cccattgctg aataccacaa aacaccatct tttttacata tccaccacag
    10861 ataaccgtat tcattactat tcattttaac cgattcttca atccacgatt tagatataat
    10921 acgtttatta ttccaaatac catcatttaa atacagaaaa ccaaatcgca acatatctct
    10981 agcactcaat gtaagtcccc agccacctat agaataaccc tgtctatctt ttgcccaacc
    11041 cttaagattt tttccaaaga aatcttcaaa accaaaatct ttcatatcat aatctggtat
    11101 aactttcata ccaataggtt taaataagta ctcattagca aattcacgag cagattttcc
    11161 agtagttttt gttataatag ctgaaagtag gtgcgttcca gctgaagaat atttgaaagt
    11221 accaatttcg cctttttgac caagttgatt caaggtatat tttatccaat ctttttgttt
    11281 gcaaagtctt tctaaagact cagtcatatt tttaaaaggg tatggtgcag tcattgtaag
    11341 taggtgacgt atagttactg cttttttaca tatttcagaa ggactacaag tatattcagg
    11401 gaaaaaatca acaacctttt ggtcaacatc ttttatatat cctttatcta ttgcaatacc
    11461 tattaaggct gatataatac tttttgtaac tgatgcaaca tgaaaagtat catcagcatt
    11521 atatccatta tagtactttt caaagacaac ttttcctttt cttgcaataa ttattccatt
    11581 tatattacta tattgtgaga ttattaaagg ttccagttgt gagagctttt ctgaactcat
    11641 gccaacactt gaagggtcta ctttttcaaa tattaaatct aagcaattgt ttttattcat
    11701 taaagatacc tccctgttat agattttgga ttttctttta gagtttttgg agaaccttct
    11761 gcaattatat aacctccttt gtcaccacct tctggaccaa gctcaacaat ccagtcacaa
    11821 acatttaata catctatatc atgttcaaca acaattacag aatttccatt ttccaccaat
    11881 tcatctaata attgaatcaa cttagaagta tcatatagac ttagaccagt agttggctca
    11941 tccaatacat aaaggatatt accatttcgt tttttaccaa tttcttttgc aagtttgatt
    12001 ctttgggatt caccaccact taaagtcggt gtaggttggc ctaattttat ataccccata
    12061 cctatttgtt ctaatacatt taagtgtgaa acaatatttg gaatatcctt gaagaaatgt
    12121 acagattcag aaacactcat atttaaaata tcatgtatat ttttattttt atatttaata
    12181 gataaagatt catcattaaa tctttttccc tgacattcac tgcatatatg gtctatactt
    12241 agattatttc ctaaccagac cttttcatat ccactaccac tacatttagg acaagcacct
    12301 ttggagttaa atgagaaatg accagctgta aatcctcgtt ctaacgattc tggctgacct
    12361 gcaaatagtg tacgtatctt atcccatata ccaatataag aagcaggagt tgagttcata
    12421 tttttgccaa taggagattg agatatctct gaatatccag aaatatgttt agtaccaatc
    12481 agtctatctg caatagtttc aataactgca taatcgtctt catcacctat ttcgctatct
    12541 gaagaattta tttgattatt gatagtatgg ttattaaatt ggcttctaag aagaggaagt
    12601 agggtgtctg atataagtga actcttgcca ctacctgatt ttccagatat tccaaccata
    12661 gcacccaaag gtaatgatac agttacattt ttaagattat ttgtatttgc attttgaata
    12721 gttatacaag gtattttatc agtatgtgta atatttttat tgcttgttct attaggcatt
    12781 ggatattttc cagatagata ctgcccagta agtgatttgt cggattgaag tagaccttct
    12841 aaatctcctt gatatactaa ttgaccacct tcaacaccag cttttggacc aatatcaata
    12901 atatgttctg ccatttcaat tgtgttttta tcgtgctcaa ctactatgac cgtattgcct
    12961 aaatctttaa gtttctttat tgattttaag atgtctattt tttctgattc atgcaatcca
    13021 gctgttggtt catcaagcac ataaattaat gagtccatct ctgaatcgag atgtgaattt
    13081 aaaaatagtc tttgcatttc cccaccactc aaagttgaca tttctcggta taaggataga
    13141 tgacctaatc gtgattctat taaatgtcga gttttggata aaatatcatt tacaagattt
    13201 gtaccaaatg tgtttaaatt accttggttt attaagattt taaggaaatc atcaatttct
    13261 aaaatcgtca tttttccaag ttctccaata tgttttccgt ttaaaagtac tctacgtgct
    13321 tcttcaccaa ttttaaaacc attgcaatct gaacaggcag tcatagtata aactccattt
    13381 aaatcctcac cccttttgta acgattgtga aatacctttg ataaagagga acttttttta
    13441 ccattttcat aatgaccata gagtacttca tttcttattt cttcaggtag ttgtaagaat
    13501 tgtatgtcta aataatcgtt gaatttttta gaaaatactc tcaaatatcc tggtgtaatc
    13561 tttgctctat ctaagacttg ttttagggta tcatgcttat caaggactaa tttttcaata
    13621 ttaatctcaa aatatgcacc atgtccagag cacttcatac acattccatc tgaagagttg
    13681 tatgagaaat aacttggtct taatcgttct tcctcatacc cacaattatt gcaaattaga
    13741 ttatcgctta caggagtatc acacatagta cacattattt gaccttctac tgaatacaat
    13801 agtgcaagca tgttgagaat attggttctt gtgcctactg ttgaacgagg attgctctgg
    13861 cgaataatat tttgttgaac agctatagtg ggagctaaac cttgaatatt atcaaactta
    13921 tcctcactat caatacctgc aagtatacct aaagattgca gatattgttt acgaccttcc
    13981 tcaaatacaa tgtcaaacat aaggctagac ttacctgagc cactgacacc tgttgcaaca
    14041 acaagcttat ctttggggat agaaacatct atatttttaa gattgtgtat ctttgctcca
    14101 ttaattttta tttctttcat tggttcacct cattttatca attttatcaa accgtaaaat
    14161 agggatatat taatccttaa tacaagaata gattaggtga ggttattaaa aaggttctat
    14221 aggtaaatat atatcgacaa agtgtctatt ttgagggtga ttgtgtgggt tgttaagata
    14281 tacttcaaaa gggaaggagg cacgtagctt ataattacca tttgatagcc attcattata
    14341 cataaaatcc cacgcatcac tatattcaga ttttgaaata tcaaaatgtc ccacaagata
    14401 ttttccagaa gggattatca tattgccaag attgtcattc tctttgacaa caatgttatc
    14461 tggaatggtc atgcaaatac tagtccttaa ttgatgctcc tgtgtaaatt gtggattatc
    14521 atgataaatg gctaatattt gtgtgttttc aagtccaagt agattctgct cacttgcata
    14581 tgtgaataac cgttctaaaa gttttgggaa agtactggtt agattaccat atgaaccagt
    14641 atatctagtg taaatagtat tcatattatc aagttctaga atttcaattt cacctttaac
    14701 ctctctagta ttcttacatt taggttttga tatgcttcta ttgtactgag aaattttata
    14761 tggttctttg caattcttgc tataattgtt tctatatttt atagggctta ttttatagta
    14821 atttttaaat gctctcgaga aaactgctga atcagtaaag ccgaagtagt gtgcaatatc
    14881 agtaacagtc atgtcagttc gatgaataag aaaagcagtt gcattttcta gttttagcct
    14941 atttacatat tgtgccaaag tttctttttc tattgctttg aagattctat gaaaatgaaa
    15001 ttttgaaaaa cctgctatat tagaaagttc atcaagagaa agaggttcat gtaaatgttc
    15061 ttctatatag tcttgcactt tgcaaatacg atttagatat tcttttttac ttttagcatt
    15121 tgtcatatat agccctcctt attgtgtaaa atgtgtatta attaatttat agcaatatag
    15181 taataaaatt ttatgttttt gcaatttatg ataaataaga tagcgtttaa ttttttataa
    15241 ttgataaaag atatttataa ttaataaaag atataagatg ccttatattt atttttgcat
    15301 ataagtatag tcttcgtaat aattagtata ccatagtgat ttatttttaa ttgtgtattt
    15361 atataaatac acaacttatg atatggacga attattatgc aaataagctg taattaaata
    15421 aattgcaata taaaccagtt gaaacataag ttagggaaat attatcaaag ttattattta
    15481 gcataagagt atagagggaa taaaataaga ttaaaaaatt acatactaaa tttaataaaa
    15541 ttattatatt aaaaataata ttaagtttat tgtttaaata aaaaagttaa atctacacta
    15601 ttaacttatt atacttaaaa ctttaaaatg aaaatatcaa agaatacttt ttaataaaaa
    15661 taatcattta ataagttatt taaaaatcta aaaactttac aacaaattat ctatttaaat
    15721 tggaggagtg ggaatatgag taatagtttt tatcaattaa attcagcagt attatatttt
    15781 aatgaaaaaa gagatgtaaa tagaataagg tttaatcact atgtaatgag aaaagaaaat
    15841 atacaaagat taaaaggaac tctgccaaga ggacaattta tgatgacagt aaggaaagct
    15901 gcatctgacc ttgatgtatc tatatctaca ataagtagac ttgtaaatga atttatagat
    15961 ttaggtatat tgagattaat aagtagggga gtaaagggaa attgttgttc tgtatatagt
    16021 tatgtttgtt ctgaaaatag taatgcagaa attgtaacaa agaatagtga tattttcaaa
    16081 aatatagaga aatacattga tgcaactatt aacaataacc aaaaaacaat gaaatataaa
    16141 catagagatg agttgttcaa gaacagtaat accaacacat acagccgtat aaatcaagag
    16201 agtatagaca aagattatga tttgataatt catactgggt atgaaacaga aaatgagaca
    16261 aagaaaaaag aattattaaa aaataattta aataaaaaga atttaaataa aaataccttt
    16321 gaaaatttgg atgaagattt gactgaagat tctacttata aaaatccaga aagcatacat
    16381 gaaattatta taagaaaatt aaatagtgaa tcaggaaaaa attttaaagc tgatttgagt
    16441 ataactaagg cacttataga taaaagatta aaagaagggt atagtttaga agatttttac
    16501 aaggttatag aggcaaaggt aagaagatgg agatatacag atatggaaat atatatagaa
    16561 ccaacaattc tgtttgggta tgaatttgag tcgtatttaa atgaggagag ttctttatct
    16621 gcttgtaatt atggtgatat gtgttatgaa gatatgtatt gagatattag ttgcttttta
    16681 gttgtttaaa atatgtttat atataaatat aaatagtgta ttaaaatgga gttgtctcaa
    16741 aatagagaga agcctcttct taattgttta aatgatgaaa atatatttga tttaatacaa
    16801 aggagagtgc cttatgagct agaaagttca ttttgagaca ctcacttttt taatatactg
    16861 gagaaatata acccatttta atggcttttg taatagcctc aactgatgat gaaacatcta
    16921 gcttgtcata tatgtgttgt aaatgatttg ataatgttct ttcacttata tacaattcat
    16981 cagcaattat ttttcttttt ttaccactac agataagctg taaaattctt ttctccatat
    17041 tagttaaatc ttcaataatt acttcagtat tttcagatgg aaaacaggtt accccttgat
    17101 agacttttaa taatgaatca attaaactat cagggctaat attcttattt aggaatccat
    17161 agatacctat ttttttagcc tcatgtttat aaactgggag gtcgtatcca gtcaagatta
    17221 ttattttaat agttgaatta gtctctaata aattataagc tacttttaag ccatcacatt
    17281 cacttaagcc tctaaggttt atatccatta agacaatgtc tattttttta tcttgaatca
    17341 tttctgaaag attatggatg tcctgtgtgg aataaaactg ttcgatttct tcgtattctt
    17401 ctagtgcaat tgacaagctt ttagcaaaaa gcatatggtc atcaactaac aaaatattta
    17461 taagaaccat ctcctttcat agggattgta atctgtacac aaactccatg aggtatatta
    17521 tcagaaatac ttatcgttcc tcctagattt tctacttgtt ctttaattga tataatccct
    17581 ttgtgtttta ttatatcaaa agtaatttta gttatatcta aaggtgtttt aaaagatgta
    17641 tttttcacac cattatcatt aatatttaat tttattatat ttttttctag tgctaaagct
    17701 atccatgcat ggctaccatt tgaatgttta tacacgtttg tcaataattc tttaatcagt
    17761 cgatatatca atatatcata tggttcaact aagaataaag tatcagaaca cttaaatgaa
    17821 acacaaatgt ttttttgtgg aaaggatgaa gaaacacttt caattaaatt ctgataattt
    17881 tcttttactg ttaaattttt taaaataaca ggatgatagt cttgcatttg atttcttata
    17941 catgtattta gattgttaag tgtttcatat ataatatctt gaacttctgg gcgatatgac
    18001 ttactcatca tgttttttat tgaaagcagg ttctgtaata tgtcatcatg taaaaaatta
    18061 gaaaactctg tttttagttg ttcttcttgt tgtaattttt ctaatgcaaa agtatacttg
    18121 ctatttttaa ctactttatt tttttcatct ctaaggttaa actccaaaat aatgttacag
    18181 aggaaaataa gcataaataa aacatttata gctattaata ttatagaaaa attcccattg
    18241 gcaaatagta cgaccaagct aattactaaa atacttataa aaagaaatat agccctttgt
    18301 tttatgttaa aaactgttga aataggaaaa ctatcatttt ctttaagtgc aataccatga
    18361 atactcataa aaaataccaa tacagttaga tagattccaa aattaccaat atgatttgat
    18421 attcttagtg taaaaaaata ataagtaagg aatcctataa ttgttataaa tactgaaatc
    18481 gatataggct ttttttcgct ttttatgaca aaaacaaccc ttttcaaatg ataaaaaata
    18541 atatataaaa agcttattat actaacaaca aactgtattc cgtacataca agcatacgtt
    18601 ctgttagaaa taaatgctcc tacaattgca ccaatgcagg tgataagcaa taaaatatct
    18661 gttatcttac ggaaattgta tccactacct tgaaacaaaa ataaaaatat aaatttaata
    18721 gagacataca ctataactgt gcttaatatt ttaaaaataa tagtgcctat tggtgtggtt
    18781 acaaatgata agagtaaata ccaactgtct agtgctagta atccacaaaa taatgaaata
    18841 atgttatttt ctcggacatt acaagaggtt atatatgtga tgtctatgag taataatgtt
    18901 gaaattatta agggaataat gctttggata ttcatataag tttcagtgct tgtagatatt
    18961 cccatgaaga gaagtgatag aatgtagttt cctaaaaata gtatttttaa attaaaattt
    19021 gtcaatctta tacacctcct tatgagttaa ttatattaat tttatgacta aatcaaacct
    19081 aagaatctat aattttaaat tatatcaaat acttataaat gaagtatacc aaatcgtcac
    19141 acctctaagc ttgacgattt ggtaaatatt aattttttaa tacaatttta caacaggatt
    19201 taatagtaag tatataatat atcaaataca ctacagaagt taagaaaatt gcaataatca
    19261 caggtatgta ttgtgaaaat gaatttccaa gtaaattctg catcaaagca gtcttataaa
    19321 ccaaggtagc aaatatacag tccaatatac caagtaaaaa cggaatatta aaaaatggca
    19381 atacttgttt tttaataatt tttttaattt gtatattatc ataacccatt ttctgtaaaa
    19441 tcttataatc agatgttgaa tctgaaattg ctgatatatt gttaaagtat aaaatacttc
    19501 caacagcaat aaagaataat accacaagaa atccgattaa cagaaatgta gaactattaa
    19561 ttgataataa atcatttatc ctgtgagaat atccttgtaa ataagggctt ccatctaaat
    19621 aatctgaaat attactatat aaattttcat tatttttaat tgatttacca ttaatactta
    19681 aaatgcttgt cattggtaat ttattttgtg ctatttgctc atatatacta tcattaacga
    19741 taagtgttcc aacgctattg gcaaaagaaa tagcattgtt taatgatgtt tcccttacag
    19801 ctacaggtgt ttctttacca ttaataagta atggataaat cgttccattt tcactatatc
    19861 catcattatt tggttgatat ttcattaaaa tacattcatt atcccttaaa ggggtaagtt
    19921 gttttagtag ctttgttcga ttttgtgcct ttaataaagt ataataatca gaaaaagata
    19981 tacattcaaa tcctgattct cttgaaataa cttctttaga agaactacta ttagataaat
    20041 tattcttaga tgtaccaatt tcatattcaa atggaaggtc ttttgatgaa gattttacct
    20101 tataaatatt tgtctgtgta aaaataatat catctgtatt agacgtatat tgactgacaa
    20161 tttgttttac atcttctatt tgtttatttt tttctactct aaattctatc tctgaaggtg
    20221 caatacgcga aacagatgca atagggtagt ataaggacag tgccataaca cttgaaactg
    20281 tcaaagtagt agcagagagt aatgtaagca taattagagt tttagagttt gaacgtatac
    20341 gatagataaa gtttggaata gctattatct tcatatctgt gtagaaagta cgtttatttt
    20401 ttttactctt ttgcataata tatggaagaa aggaattgat aaagagaact gtaccaatta
    20461 caatgataat catagttatc aagcccattt gataaaatcc aatacttacc catactgatt
    20521 tagctccacg aagaatatct agtgataaac aatacccact taaaatcata ataaatccca
    20581 taaaggctgg aatttttctg aactttaatt ttttttctgc acttttttca tgtcttatca
    20641 attttacaag tgaagtctta taaagaaatt taccatttga tatagctaag actaaaacaa
    20701 ctaatgctat aaagataatt gttttgttta ttgcatttat attaaaaaat ggtatctgtg
    20761 aattatcaat tgataaatta agtagtgctg taattccaaa gacaataccc ttatgtgaca
    20821 atgctcctaa taccaatcca gtaataaaag ctccactaca aattaataca ttttcaaagg
    20881 taagtagcga taatattgta aacttacgat agccaagtaa agcatatatg cctaattctt
    20941 ttgtacgacg tctcaagaag aatcgatttg agtatgccat atagaagatg acaaatgcca
    21001 tcaaaaatat cgaaataaca ttacacatag attcaactct accatcagtt gaaatttttt
    21061 ctagcattat cttattaaca gagaatgaag taaatgcgaa aaatacagta ataacaaaag
    21121 agactgaaag tagatataga gaatagaatg aaaagttttt tttaagattc tttattgcca
    21181 tataaaaaat gttcattaaa ttatcctcct atcttttagt atccaatttt gcaatttctt
    21241 gaataatcaa ctcataaaat gtatgtctat tattcggttg tttatttaat tctttaatga
    21301 tatgaccatc tttaaaaatc aaaattctat ttgcaaaact tgctgcatag gcatcatgtg
    21361 ttaccattaa aattgttgtt ttcaactcct catttgcttc ctgtagtgag tggagtagtt
    21421 cagtagctga attagaatcc aaagctcctg ttggttcatc tgcaaagaga atactaggat
    21481 gttttactat tgctctaact gctgaagctc tctgcctttg cccaccagat aattcatttg
    21541 ggtatttatt taattgagaa gctatgtcaa atcgttcagc tagactcttt accatgtttt
    21601 ctattttatc tggattgagt ttctgaagtg taagaggtac tgaaatattc tcgaaaattg
    21661 taagactatc tagtaaaaaa tactcttgaa agataaagcc taaattatcc ttacgaaaat
    21721 cagcagcaca agtgtcatta agcgatttca aatttatatt atttatgaaa atatctccac
    21781 ttgttggttt atcaattgta gataatacat taagcagagt tgttttccca gagccagaag
    21841 ctcccattat acctataaat tcaccttctg atacattaaa ggatacctta tctaaactcg
    21901 gctgttgccc tttattataa gttttagtta tgttatttac ttttaatatt gtattcattg
    21961 tatatgtctc ctttcgtctt aatatagtca aattatatat taaccttatt gtttcttcat
    22021 gagtaaatca cgcaataatt ctacacaaat tacttatatc acaatatatt gtttaaaatc
    22081 taactttatt aggtttggga tgatggacaa gattttaatt taaaagagtg catagatata
    22141 taatggcata atgtagattt aaattaaaaa aaataaaata aagccataaa tattgaaaaa
    22201 ttcaatattt atggctttat tgcttgtaat aattaataga atatatattt tttattaatc
    22261 atctatttca aattctaata ttttaccagt aattgcatta attgttatct catattcaat
    22321 ttttcctttt attatttcac cttcatattc tttgtcatct tcatcatact taaattttac
    22381 tattttccca ccaggcactt tatctagcat tattgattta gctttttcag cactaataat
    22441 agaactgttg tcattagtat tagagttatt cttatcatta tcatcaaagt catcatcaga
    22501 atcattgtcc atgtcaatat ctacaattct tccatcaaat gcacttatct ctaattcata
    22561 tgttttctta ttttttatta ctttagcctc atattcgtta tcttcagcat catatttaca
    22621 atagattaaa ttaccattag gaacagcatc taatgctata gacttagctt tatccaatga
    22681 tatattttgt gtacctaaat tattatcatt taagtcatca tctttttcaa tttctattat
    22741 tttaccagag taggcatcaa tttctatctc atataggata ttatccttta taactttgca
    22801 gtcatattca ttatcatctt catcataata acaaactaaa atatcgcttc ctggaagagc
    22861 ttgttttaat atttctttag cctgtattaa agatattttt ttagttttat ttcttatgtt
    22921 cacatttttt agttttaaaa tatcttcaaa tgctttttga ttatatcctc ctcctacttg
    22981 tgttatttca tctatatctt tatttttaat aaattccttt tgactattta caaggctacc
    23041 attagatatc attataggag aattttcttt agcagctaat actcctattg ataatgaatc
    23101 tactaatgca ttttcttggt taataccatc tttagctaca aatacattat ttattttttt
    23161 atctttataa aatttatcaa taatttttgc attagtattg tttctatctg aaccactgat
    23221 tctttctctg tttggatatt tctttactgt attgtctgat aaaatcttat ttcctccaac
    23281 tatgtaagat ttttttatag acctattgtt taagaaattt atactactat cattgctgtt
    23341 ttcatctgat actaatatta taggcatatt atgtattgct gctggagaag ctatactaac
    23401 tgcatcagat aatcccttta gtccatttac aactgcaaca ttttctacct tttttatctt
    23461 atctatttct ttaagtacat ttgtagacat tttatatata ttgtttccta ctattttatt
    23521 tatttttatg ttaagtgatt ttatttcatt ttctacttta gaagaaatgc tatttccact
    23581 atctacaatg tacacattat ctacaccaag ccttttaagc tcagccttag ttgaattttc
    23641 aatactgttg ttgtttacta aaagtatagg tgcattcttt agcttagcaa atggatttgc
    23701 acaaagcgca ctttgaatag aattaccatt aactataatg gctgtttttg attgaaccca
    23761 tcccaattta cttacttcta ctgctgtttc atatcttgtt ttacctatta atctttcttg
    23821 ctttgtagta ttgtctgcaa aaattgctga agaactagaa aaaaacatca tacctgatat
    23881 taatatagct aaatttttat tattcatatt tttacctcac aatctttaaa aatttgttat
    23941 ttagcatact taataaaata taatcttaaa atcaaattga tactgagttt gaagttacaa
    24001 aatcaacaaa taagatttct ttaatacaaa attttccttt ttatatttaa cattgtatca
    24061 caaatataaa aaggaaaaaa ctttttaaaa agggtataca ctattcattt tttatcttat
    24121 aaataagtct ttaccactgt tttatatatt ttaaaataga cacaagacct atttctaaat
    24181 cttttataaa tattttaggt gaaatttctt tttaaacata tctaaaaagt atttgtagta
    24241 atattaatgg actgaatttc ttaaagtata tatttctttg catgttggag tttgtgaagt
    24301 ttgagaattg gagggtgaaa gaaacatgca atggattaat attaaagaac tgtattttta
    24361 taatatttgt cttaaaaata aaaaaatcta ttgacttgaa gttaactcca agtagtaaag
    24421 tataattata caagaattat atacttgtaa gaatagttaa agtagagaga aaaaacaaac
    24481 aagttttaaa gggggaagta aaacaatgga ggcaaaaaaa ttaggatttg gattaatgcg
    24541 tttaccaata aaagatgaaa atgatgttac aactattgat atggaacatt taaataaaat
    24601 ggtagacact tttttagaaa ggggatttac atattttgat acagcctatg tgtatcacat
    24661 gggaaaaagt gagatagcac ttagagaatc tctagtaaaa agacacaaaa gagagagttt
    24721 tactatagct acaaaacttc cattaatggc tttaaagaaa aaagaagagc aagaaaccat
    24781 ttttaatgag caattagaaa aatgtggtgt agactatttt gactactatc ttttacacaa
    24841 tataggcgtg tcacattatg aagtagctaa aaaatttgat agctttaagt ttattgaaga
    24901 aaagaaaaaa gaaggaaaaa taaagaatat tggtttttct tttcatgata gtgcagaact
    24961 attggataaa gtcttgagtg agcatccaga agtagacttc gtgcaattac agattaatta
    25021 tttagattgg gataatgaaa gcatacaatc tagaaaatgc tacgaggtgg cagagaagca
    25081 taataagcct gtaattgtta tggagccagt aaaaggaggt acacttgcaa agataccaga
    25141 aaaagcagag aaattattga atgactacaa tccagatatg tcaatttcat cttgggcaat
    25201 acgttttgca gcaagtaaag ataatgttat gatggtctta agtgggatgt caaatatgga
    25261 acaattatta gacaatacag gatatatgca aaatttcaaa ccattcgtac aagaggaata
    25321 taatattata gatgaagcag tagagattat caacgaatca attttagttc cttgtactgc
    25381 ctgtcagtat tgtgtagaag gctgtccaaa aaatatcgct attccaaact attttgcgct
    25441 gtacaatgca gaaaaacaag ctcttaatac tggattttca acacagatgg tttactataa
    25501 taattatact aaaacttatg gaaaggcctc agattgtatt gaatgtaaac aatgtgaaga
    25561 aagctgtcct caacacatta aaattataga tgctttaaag aatgtagcag aaacctttga
    25621 gaaataattc aatctataca atatcaagag gagaagatat gtatgacgat ttcagaagtt
    25681 agtaaaaaat acgagctttc agcggatact ttacgatatt atgaacgaat tggtttaata
    25741 ccacctgtaa atagaaataa aagtggaatt aggtctttta cagaagaaga ttgtgagtgg
    25801 gttaatttca taaagtgtat gagaggtgca ggtctttcta ttgagacatt aattgagtat
    25861 gtagctatgt ttcaacaagg gagcagtact atcaaagcta gaaaagaact tttaatagag
    25921 cagagaaacc aactagcaaa aagaatagaa gaaatgcaaa aaactttgga acgattaaat
    25981 tttaagattg atagatatga agaaggtatt attgagaaag aaaaagtatt aaagagcagt
    26041 agaaataaga aaatggaggc agtatcttat gagtaaaaat gtattaatag tatcagctag
    26101 tcctagaaaa ggtggaaatt ctgacttatt gtgtgaccag tttatacaag gggtattaga
    26161 atctaaaaat caagtggaga agatattttt aaaagataaa gatattaact attgtactgg
    26221 atgtggtgct tgttatgaaa aagaagcaag ttgttcacag acagatgaca tgggagaaat
    26281 tcttgaaaaa atgattgggg cagatgtgat tgttttagcg actcccgttt atttttatac
    26341 tatgaatgcg caaatgaaaa ctatgattga tagaacttgc tctagatata ctgaaatttg
    26401 tgataaagat ttctatttta tcgttgcagc agcagatgaa aatgtggctg atatggaaag
    26461 aacaatagaa ggatttagag gatttacatc atgtctaaat ggttctaaag aaaaaggtat
    26521 agtatatggt gtaggtgctt ggaatgtagg tgatattaag ggaagtaagg caatgaaaca
    26581 ggcatatgaa atgggtaagt tggcttagta tgtttgtata aaattgtata aaatcgaata
    26641 tattcttatc atttcaacaa taaaaagagg cttatctata ttttgagaca gcctctttgt
    26701 gctatatcat ttatttttat tctatatcct tattataccc tttatttttt tatgcctatt
    26761 taagtatctg ttgttactca tatattttaa taattaccct taaaaaacta tacagattcc
    26821 tgcataatat tattttcttt agtaattaat ttttctaggt ttttccaatc catttcttcc
    26881 atatttgcaa aataatgacc acttcctatg caagtcagat aagactttcc atctaaatca
    26941 aacgaagaac ctccaataca ctttgaatta catttcttac aagtacgagt tttagttata
    27001 ctatctttaa tagttttaga gcattcctcc acagcatctt tatatgtatt tagatgaaaa
    27061 agatttgctt taactctcca ttttttttca ttacattcaa tagtaaataa gctacgtttt
    27121 ggtttcttag ttgaatatac tattttgtaa gaacgagcac ctgtttttgg ttcaatttta
    27181 caatctaatg atttaccaag ttcatgtaaa tgacatgcaa tatcataatc tttaccactt
    27241 agtacttcta acatttcttc tgttgtttct gccgttaatt cacttttgct catattaaaa
    27301 aaatccccct atataagtaa taatttcaca tgaaaataat taatataagt atattaaata
    27361 aaactattaa aatcaataaa attactacaa tcttacatta ttgggcatag aatgagagct
    27421 aatgatttat tagaaataag acttaatagt atgaaaattt acttagacgt ggtacaattc
    27481 tataaaagat ttaaaactag gaaaggagaa agttgttgag atacggccaa tataacaatt
    27541 tatttataag ttgtaaattt attatgagat taattagatt gttaagtaat actatcaaaa
    27601 ggtagttttt tggattttca gcaacagtgg tagatattga taattttttg gttattatta
    27661 tatttagctg ttatattttc aataggctct atgataacta gggtaaataa ggtatgggta
    27721 aaggttttat tatttataat agtgggattg tcaactatag ttctttcata tgtaataact
    27781 tgataattta agattgaaaa ataactttaa tctgtaaatt ctcaaaacaa gaattctcat
    27841 gttggtaaat ttctagatat gagaaaaaaa ttgacatcat aaaaaagtaa ttttaaagca
    27901 tttttttacg aaaaaattca gaagtaacta ttttgaatga cttcacaaaa ttttatatat
    27961 aaataaagtt tggcacgtta attgctttaa taaaagttaa caagacacaa ataaacataa
    28021 tcatctaagt attgattatt tgaagtttta gatttgaaat ttaatctaaa ggttcgtatt
    28081 aatattggtg tttaggaaat tttattttcc tgtaaatata acttaataat aggaggtgaa
    28141 gtcatgtcaa aagtagtaat agctacagag aaagctccag gagcaattgg accatattct
    28201 caagcaattc aagttggaaa catagtttct acatcaggtc aacttccaat agatatgaag
    28261 actggcgagt tagtatctga cccaaaagaa gcaacaaaag cttctttaga taatgtaaaa
    28321 gcaatattag aacaagctgg tacaagtatg gataaaatat ttaagactac agtattcgta
    28381 aaagatttaa aggattttaa tgatattaat gaagtatatg ctacatattt taaagaaaat
    28441 ccaccagcaa ggtcatgcgt acaagttgct caattaccaa aagatgcagt tttagaaatt
    28501 gaagcaatgg cagtattata agtattataa caataaaacc aataacaaaa ctaataaaaa
    28561 ttaaaaacta ataaaaaaag tctacaatta aaaaagttta tattaaaaaa gtctatataa
    28621 aaatctatct aaatatttaa ctattgagct tttctcatat aatgtatatt tttatgtcaa
    28681 aaatatattt gttatatgag gaaagctttt tttattttat tattgtattg tgatttactt
    28741 tattgtctgt atcttataat taagtaatta aggtcatcat ataaaacaaa ctttttataa
    28801 attaatattg tgtgttttaa tgtaaatata taaataagta atgttttata tatattttaa
    28861 agagtgacta tatgttaaaa tatagctaaa ctgataattt ggtaaattaa attctaatgg
    28921 gggaaactat gttaagtaaa ttaaaagaat ttcaacaaga aatgataaaa tacactgaaa
    28981 cagtagctag tgtgttagat gtagatattg aaatagttga tgatagatta ataagaatta
    29041 gtggtacagg tctgtataaa tcaaagataa atgaaagcgt tgttacagaa ggatttattt
    29101 acgacaatgt tatacagaca ggtcaggaat tagtcgtatt ggatatatgt gataatcagc
    29161 tttgtataga atgttcccat tacatgaaat gcctaaataa agtaataata gcagttccaa
    29221 taaagtataa taatcgaact ataggagtaa ttggtgctat tagtacagat aaaactaaaa
    29281 aagtagaaat aagtgcaaaa atagataatt atttaaaatt tgtcaatcat atatgcgatt
    29341 taatttctat gaaaatagaa gaacatgaag cgtcaaaaaa tagcagtaga aaaatggata
    29401 tgatgataga aatcattgaa aatgttgaaa aaggcgttat aatactagac ataaatagca
    29461 aaatatctta tataaacaat atagctctaa aaaaattaga tatatataaa aatataatag
    29521 aaaatatagt aaatatagta tctgttgaat cttcctcaaa tggacatgaa ttactagaaa
    29581 ttgatattga taacaaaatt tataatataa atgccaaaat aattccggta tatccatata
    29641 taaatcaata cgacaaaata ataatatttg acaagacata tatcaatcat aaaggacatg
    29701 gaaaagtcaa tagtggctgg ggaaatagtg atatagagtc tataattgga aattcagagg
    29761 caatgttaaa agtaaaagag agaactaaga aattagcaaa gtcaaattca actgtactta
    29821 taactgggga aagtggtacg ggtaaagagc taattgctag ggctatacat gctgaaggta
    29881 gcagatggaa caagccattt attgcgataa actgtgctgc tattccagaa aatctccttg
    29941 aaagtgagct atttggctat ataaaaggtg catttagtgg agctagtagt ggaggtaaag
    30001 taggtaaatt tgaacttgca aatgaaggtg ttatatttct tgatgaaata ggagatttgt
    30061 caatgccttt acaagcaaag ttacttagag ttttacaaga gagaaaattt gcgagaattg
    30121 ggtcaaataa acttatagat ttagatataa gagtgattgc tgctacaaat aaaaacttat
    30181 tgaaattagt aaatgaaggt aagtttaggg atgatttata ctatagatta aatgtaattc
    30241 ctataaattt gccacctctt agggaaagaa aggatgatat tgaggcaata atgatgaagt
    30301 ttgcttctaa atattcttta gaattaggta ttcagttaaa taaaatagaa gaaaatgtaa
    30361 tgaatatgtt gattaactat aattggccgg gaaatataag ggaactggaa aatgcagttg
    30421 aatatatgat gaatttggtt ggagatgatg gaataatata taaagatatg cttccattgg
    30481 atattttaaa ttattataat attaatggaa atgtttgtaa aaataaggat ataaatataa
    30541 tatttgaaga tgacatagtt ggagggatag tagagaatca ggaaaggata ctttcaatta
    30601 aagaattaga gttgacttac ataaacaagt tgttgaataa gtatggaaga gatacaaaga
    30661 cgaagaagaa gatagcaaag gatttaggta taggtttggc tacactatat agaaaattgg
    30721 aagaggaaca gtagtaatat aatattaaaa tgataggtat ttgtgtgttt ttatagatag
    30781 gtatttttac tttatggtgg aggtgttatt atgcaatatg cgatagagct atattatgat
    30841 aaaaaaacgg aaaagcaact ttttgattta tctaaaaaaa tcgctgatga aaaaattagt
    30901 acgaagtact tagaatggaa aacaagacct catcttactt tggcttgttt caatgatgtg
    30961 gatgaggctt gttgcataga caagctaaag gggtttgcac aaaaccataa ggtaatacct
    31021 gcttacattg gttcagtagg catgtttaat gatactaaaa cggtgtttgt atcacctata
    31081 atgaatagca gtatgtatca gtttcagaga gaattatatg aggtactaca agattttgat
    31141 tcaaatggtt gggaatggta ccaccccaat cgttgggtac cccattgcac aatagcactt
    31201 actggagatg atgaaagtga ggcttttttt cgggcaagtg atgtattact gcgtgagttc
    31261 aaaaaaataa gtggtgagtt tgtctcaata ggattggtta aaattacatt tcctgtggaa
    31321 gaaattttta cagtgaatat gaataggtaa ctttaactct gttgtggatg ttatgaatat
    31381 tttgcatagt gcatttcatc agataaatgc gaagttgcga atttcgacag ctcaatagtc
    31441 gcaagtagga cacaatggta cacatattgc acttttgctt attggaggga cgcccatgta
    31501 aacttctgta agaagctatg aaaagattta agccattttg gaggctttgg gtaataaaga
    31561 atatttgggt aataaagaat ataaagtata taaatttata gagtttatgc gtaagaaggt
    31621 tatagccata tatttataga aaataaaagt agtaatatat ctgacaaaac aatagacata
    31681 taaaaaataa gagcataata aaggaagaat taaaataaat aaacgatttc tcgaattgat
    31741 aattctcgta ttgataaaaa tttcccaata tgagaatttt ttcttttata aatcttattt
    31801 ttcacattta atatttataa aattcaaaga aattttataa atatatgtaa ttccaacata
    31861 aaaaaattgt ttttagaata aataatattg gcatagtaat tgcttcacta taagacacaa
    31921 agataaaaaa ttaaaatgac accgaaaaat ttgaaagggg aatataaaat aaatgagaga
    31981 aataaaatgg aaattaaata acttacctaa atcagaggaa aaagaaaaag gaattgagtt
    32041 tttaagagat gaagaaattg caaaggctaa agcttttcat gagagctttc cacaatatga
    32101 aaaaactcct ttagttaaat tagataactt agcaaaatca ctaggcgtaa gcggaatata
    32161 tgttaaagac gaatcttata gatttggttt aaacgcattt aaagttttag gtggttctta
    32221 ctctatgggt agatacttag ctcaaagatt agatacagat atatctgagt tagggtatga
    32281 caaattaact tcaaaagaaa taaaagaaaa attaggagaa ataactttct ttacagccac
    32341 agatggaaat catggtagag gagttgcttg gacagctaat aaattaggtc aaaaatctgt
    32401 tgtattaatg ccaaaaggtt cttctgaatt tagattaaat aaaatcaaag gagaaggtgc
    32461 agatgctagt ataacagact taaactatga tgatgcagta agattagcta atgattatgc
    32521 agaagctgat gaccatggag taatggttca agatacagca tgggacggat atgaagaaat
    32581 accagcatgg ataatgcaag gatatggaac tatggctaaa gaagctatag aacaattaaa
    32641 agaatatgga gtagatagac caacacacgt atttgttcaa gcaggagttg gttcacttgc
    32701 tggtgcagtt caagggtatg ttgcttcaat atatgatgaa tgcccaataa cagtagtagt
    32761 agaggctgat gaggctgatt gttactataa atcagcagaa gctggagatg gaaaaccaag
    32821 atttgttgga ggagatatgc caactataat ggcagggctt gcttgtggag aaccaaacac
    32881 tataggtttt gaagtgttaa aaaattattc atcagcattc gtttcagcac cagactgggt
    32941 atctgctaaa ggtatgagaa tattaggaaa ccctctaaga ggagatgaga aagtaatctc
    33001 tggagaatct ggagcagtta caactggagc attagtttca atccttgaaa gtgaagattt
    33061 aaaagactta agagaagctt tgaaactaga tgagaactct aaagtattat taataagtac
    33121 agaaggagat actgaccctg ataaatatag agatatagtt tggaatggtg aatgccaaag
    33181 taaataaaag acttaaggaa aataaaaact taacaaataa atgaaaaatt taaggaaaat
    33241 aaaaacttaa ataagtgaaa actttaaata aaataaaaac taaaacaaat gaaaaatcta
    33301 aataaatgaa aaagtaaagc aaatgaaaaa ttcaaaataa aaactaaata aaattaaata
    33361 aaaccaaata aaattaaaat aaagtctaaa taaaaattta ataaataaaa tataaagaaa
    33421 taaaaaatca atagattaag tgaaatgcta ataaattaaa aaagtgaaat atcaaaataa
    33481 aacgtcaaca aattaaaaat tatatggggg aatatcaaaa tgttaaatga aacaagaaaa
    33541 aaacaattaa ctgaagtatg ccaagactta ataagaaatg ctagttattc aggtcaagaa
    33601 gaaaacgtag taaaagctat agaagaaaat tttgctttac taggttttga tagttggtca
    33661 agagatagat atggaaatat agtaggatgt ataaaaggaa ataaaccagg taaaaaaata
    33721 ttatttgacg ggcatataga tacagttcca gttccagatg caagtaaatg gagtgttcct
    33781 ccttttgaag cgagaatagt agatgggaaa atatatggta gaggaacttc tgatatgaag
    33841 gggcaagtaa gtgctatgat ggctgctgtt tcatactttg cagaagatac taacaaagac
    33901 tttgaaggtg aattgtatgt agcaggtgtt gttcatgaag aaatatttga aggtgtttca
    33961 gctagagaga taagtaaggc tgttcaacct gattatgttg taataggtga atcttcagaa
    34021 ttaaacttaa agataggtca aagaggtaga ggagaaatag tagtagaaac ttttggtaaa
    34081 ccagctcact ctgctaatcc agaaaaaggt a
//
LOCUS       DAEQJM010000040        34015 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.040, whole genome shotgun sequence.
ACCESSION   DAEQJM010000040 DAEQJM010000000
VERSION     DAEQJM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34015
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.040"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(216..959)
                     /locus_tag="KRQ43_002305"
     CDS             complement(216..959)
                     /locus_tag="KRQ43_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH2742657.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
     gene            1125..3692
                     /locus_tag="KRQ43_002306"
     CDS             1125..3692
                     /locus_tag="KRQ43_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2742658.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNNSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAVDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            3922..4326
                     /locus_tag="KRQ43_002307"
     CDS             3922..4326
                     /locus_tag="KRQ43_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2742659.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            4350..4847
                     /locus_tag="KRQ43_002308"
     CDS             4350..4847
                     /locus_tag="KRQ43_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742660.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            4850..5251
                     /locus_tag="KRQ43_002309"
     CDS             4850..5251
                     /locus_tag="KRQ43_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBH2742661.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            5269..5757
                     /locus_tag="KRQ43_002310"
     CDS             5269..5757
                     /locus_tag="KRQ43_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742662.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            5784..6539
                     /locus_tag="KRQ43_002311"
     CDS             5784..6539
                     /locus_tag="KRQ43_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH2742663.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            6539..7402
                     /locus_tag="KRQ43_002312"
     CDS             6539..7402
                     /locus_tag="KRQ43_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH2742664.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKKKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            7449..7928
                     /locus_tag="KRQ43_002313"
     CDS             7449..7928
                     /locus_tag="KRQ43_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HBH2742665.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            7993..9300
                     /locus_tag="KRQ43_002314"
     CDS             7993..9300
                     /locus_tag="KRQ43_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH2742666.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETDMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            9611..9751
                     /locus_tag="KRQ43_002315"
     CDS             9611..9751
                     /locus_tag="KRQ43_002315"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HBH2742667.1"
                     /translation="MNGEGCILSNKITKECYKTGYMIREKSIDTYPDSGRGFMTWDEN
                     GE"
     gene            10263..11357
                     /locus_tag="KRQ43_002316"
     CDS             10263..11357
                     /locus_tag="KRQ43_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2742668.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQTQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSLLSENKEYKFLIEKLSLLEE"
     gene            11362..11562
                     /locus_tag="KRQ43_002317"
     CDS             11362..11562
                     /locus_tag="KRQ43_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HBH2742669.1"
                     /translation="MENLMEYLPLLIPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            11562..12479
                     /locus_tag="KRQ43_002318"
     CDS             11562..12479
                     /locus_tag="KRQ43_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742670.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLEPDSGTIDVCGEKVTYGRTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIKIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNNEIQKFKSSGGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            12476..13234
                     /locus_tag="KRQ43_002319"
     CDS             12476..13234
                     /locus_tag="KRQ43_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742671.1"
                     /translation="MREYIAFTKKEFKENIRNYKLLSLTILFLVFGIMSPLSAKFMPD
                     LIAHFAPTLKVTTAPTALDSWTQFSGNISGLGTSLTLIVFCNILSNEYSKGTLVIMLT
                     KGLSRSSVVLSKFSIAVIIMTIGFWLSFLCTYGYTMYFWPTANLNHIIFSAFNLWLIS
                     IMYISILILGCVLFRPAFASVLLVLAATAILSLISIPKQIAPYTPNFILSKNIDLVSG
                     KVTPPEFIIPIIVTIVISIVCLLLAVVLFNKKAV"
     gene            13617..14690
                     /locus_tag="KRQ43_002320"
     CDS             13617..14690
                     /locus_tag="KRQ43_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH2742672.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            14760..15023
                     /locus_tag="KRQ43_002321"
     CDS             14760..15023
                     /locus_tag="KRQ43_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742673.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            15229..16206
                     /gene="bioB"
                     /locus_tag="KRQ43_002322"
     CDS             15229..16206
                     /gene="bioB"
                     /locus_tag="KRQ43_002322"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBH2742674.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMVFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            16434..17447
                     /locus_tag="KRQ43_002323"
     CDS             16434..17447
                     /locus_tag="KRQ43_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH2742675.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNSAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDVSVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            17489..18379
                     /gene="rbsK"
                     /locus_tag="KRQ43_002324"
     CDS             17489..18379
                     /gene="rbsK"
                     /locus_tag="KRQ43_002324"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBH2742676.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIKVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKKLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            18427..19389
                     /locus_tag="KRQ43_002325"
     CDS             18427..19389
                     /locus_tag="KRQ43_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH2742677.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            19443..20954
                     /locus_tag="KRQ43_002326"
     CDS             19443..20954
                     /locus_tag="KRQ43_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH2742678.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            20938..21936
                     /locus_tag="KRQ43_002327"
     CDS             20938..21936
                     /locus_tag="KRQ43_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBH2742679.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            22120..23382
                     /locus_tag="KRQ43_002328"
     CDS             22120..23382
                     /locus_tag="KRQ43_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH2742680.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIGGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFQMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            23402..24145
                     /locus_tag="KRQ43_002329"
     CDS             23402..24145
                     /locus_tag="KRQ43_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBH2742681.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            24318..25703
                     /locus_tag="KRQ43_002330"
     CDS             24318..25703
                     /locus_tag="KRQ43_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2742682.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFEYTPII"
     gene            complement(26040..26684)
                     /locus_tag="KRQ43_002331"
     CDS             complement(26040..26684)
                     /locus_tag="KRQ43_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH2742683.1"
                     /translation="MNNLDKNNVNEVLDMLLRTRRSIRSFTKEVPSKGLIEEIIETGR
                     LAPYAILSVAKQTDFRHFFVISNNSLQMNKIKTILVDVIKTQISVNEKKAKNNITLQS
                     FITSLKMQVEKGVLGIGTAPYLIIVAERRGIPPIEQKSLSHVMQNMWLKSTALGLGFE
                     LVSVIGRLSDNKDFCDILGVPTGEYGFDACAIGFPTTSVTREGRAIPHPSIKWI"
     gene            26948..27562
                     /locus_tag="KRQ43_002332"
     CDS             26948..27562
                     /locus_tag="KRQ43_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBH2742684.1"
                     /translation="MKKVSIDRRTIRTKKMIRSALAELIDEKGFNNISVTDLTQRADI
                     NRGTFYLHYVDKYDLLERIENEIIQEIEEETKHLDSSNMMEIDTSSEPLPFMVKLFEY
                     FRKNSVIIKSILGPKGDPTFERKIKKFIETNLFEKQKLINFNIDEAIISEEYFIQYIL
                     SADLGVIQYWLEKNMKESPEEMALILARMSLLGPLRAVGIRKDS"
     gene            27783..27923
                     /locus_tag="KRQ43_002333"
     CDS             27783..27923
                     /locus_tag="KRQ43_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742685.1"
                     /translation="MKNENISYLALGLCFGVVLGSLFKNLAIGLSFGLVIGVVLDSKK
                     NK"
     gene            complement(28153..28600)
                     /locus_tag="KRQ43_002334"
                     /pseudo
     CDS             complement(28153..28600)
                     /locus_tag="KRQ43_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002599264.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            29370..30209
                     /locus_tag="KRQ43_002335"
     CDS             29370..30209
                     /locus_tag="KRQ43_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742686.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            30199..30642
                     /locus_tag="KRQ43_002336"
     CDS             30199..30642
                     /locus_tag="KRQ43_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742687.1"
                     /translation="MYSNTYNNENFMRARAFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            30653..31144
                     /locus_tag="KRQ43_002337"
     CDS             30653..31144
                     /locus_tag="KRQ43_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742688.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(31346..32074)
                     /locus_tag="KRQ43_002338"
     CDS             complement(31346..32074)
                     /locus_tag="KRQ43_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH2742689.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            32199..33287
                     /locus_tag="KRQ43_002339"
     CDS             32199..33287
                     /locus_tag="KRQ43_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742690.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLIIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKELMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            complement(33725..>34015)
                     /locus_tag="KRQ43_002340"
     CDS             complement(33725..>34015)
                     /locus_tag="KRQ43_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742691.1"
                     /translation="NMGMPNNVPNNMNSNMGYNMNNTMGIPNFSCNQNMPPNVLMMIP
                     GVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQATNIEEFDEEEM"
BASE COUNT        13264 a         3547 c         6108 g        11096 t
ORIGIN      
        1 atgatatttt tttagcttta tactataagg tatataaaac taagcctatt aaaaatgtta
       61 taatttctat taccatcata gaccatatca atccatcaag ttcataaaag taattaagct
      121 ttattaaata gcttctttat tataatttct ttatttcata taatataaat agtattaaaa
      181 tttttatggg agttaaagta agcatgtatt attacttaga tatttgtata atcaacatct
      241 agtaatttac ctttttggtg aaaatgatta ataagttttt taggataatt cattattaat
      301 tcatctggaa aattaatttc ctttaagata ttctcagaat actcatagtt acctatgtca
      361 aaacaaatgt gagcatctga agttagtatg attttagcac catatttttt gcaaagtgta
      421 gcaatatact tacagttatc cgagctacca tttcttgaca cgcctttaat agaacaatta
      481 tttatttcta ttaagatatt cttttctata gctaatttaa tgattaattc atagtcgatt
      541 gggtagtttg ggtttccaag gtgtcctaat atttcaatat tatcatgctt atttattgca
      601 tttattaaag ctttagtatt attctctaat gtatttggag aaaaaacagc ttcgtgaaat
      661 gacaagataa gataatctaa ccgaggaatt acaaaaggct ctaggtctat gtttccttta
      721 atatctagta tatttgcttc acagcctctt aaaattataa tgttatttat gattcttggg
      781 atattttgaa tgttgtgaaa gtaccatctg tggggagaac caggcatctt aggaccatgt
      841 tcagatgtac ctagtatctt aattccattt tctttacaat aattaatatt ttctagtaaa
      901 gtgctatagc catgaccact gactatagag tgggtgtgta aatctgataa aaaattcata
      961 taaattcctc ctctataaaa gatgagggta acgtaattta tattataaaa cgaataggaa
     1021 agaaaatcaa tagttacata attagacaaa aatattaaaa tattgtagaa ttaagcttaa
     1081 taataaatgt ttaacagtat tactgcttat aggggaggtt aactatgaca caaaagaagc
     1141 tatcaaggaa agaaaaagtt ttaatttgct tgaaaaggtt aacagaagaa cacttgaact
     1201 ttaataatgg cattagattt ggatttgatg cagaatatat agctactgaa gtaggtataa
     1261 atagaagtaa tgctagtaag gaattaaatc aattaataaa agaaagtatt attataaaga
     1321 taaagggtaa gcctgttcag tacttatata aagaaagtat tgagagtatt ttgggaaaga
     1381 aactaaataa agggatattt gataatatta actctataaa cgaatatagt gaaaatgatt
     1441 ctatcaaaga tgagtatatt ttagagagta taaaaaaaga gaacaatatt tttaatttag
     1501 taggatgtga tggaagttta aggtcccaaa tagaacaggc taaagcagca gtaatatatc
     1561 cacctaaggg gttgagtaca ttaataatag gacctacagg agttggtaaa tctatatttg
     1621 cagaatatat gtataagtat agtttaacta taaaagaaga tagtgataat gcaccattta
     1681 tcatatttaa ctgtgctgat tattctgata atcagcaatt attattagcg cagctttttg
     1741 gatatgtaaa aggagcattt actggagctg ataaagataa gtatggtatt gtacatgaag
     1801 ctaataatgg agtattgttt ttagatgaag ttcatagatt atctgcagag ggacaagaaa
     1861 tgctatttct gcttatggat aaagggatat atagaaggtt aggagaggct aataaggtac
     1921 acgagtgtag agttatgata attgcagcca ctacagaaga cccagaaaca gcaatgttgg
     1981 aaacgttttt aagaagaata cctgtaacta taaagattcc gtctttagag gaaagaggct
     2041 ttcaagagag aatgaagctt atatgttatt tttttaaaga agagagtgtt aggattggtg
     2101 ttaagttaaa ggtttcaaaa gaagttatta aggcatttat tttatataag tgtaagggaa
     2161 acataggcca attaaaaagc gatatacaat taatttgtgc aagagctttt ttagattata
     2221 tgacctataa aagggaatgt gtatatgtaa ggctctctct tctaccaaat aatattagag
     2281 aatcattata tggaaataat agaaaagagg agtttgtaca aaatttcagt tttattggaa
     2341 aagatgatat tattttttta ccagaagaaa aggattttga aagtgaaaat ttattaatag
     2401 aaaataaaaa atatgattta gatttttatg gaatgataaa agaaacttgg aataaacttc
     2461 aacaagaagg tattaaagag tcacaaatta gaagtgttat agatggagac atacagaagt
     2521 attcctataa tttaatgaat acttttatat ataataatag taatcaaaca gcttataaca
     2581 acattgttaa tgattcaatt gcaactactg taaaatatat tttacaaaag catgataaat
     2641 ggagcaaaag agaaggatta gataaattaa taaaagctat agccttacat attcagaatt
     2701 taattgaaag aataaagatt ggaaatatag taaagcatcc taataaagat gaaattatga
     2761 aggaaagagc atatgaatat aacatagcaa aagaaatatt atctaacatg tcattaatgt
     2821 atggagtaga gtttccagaa gatgaagcaa tttttttagc aacatttctt tatttatcgt
     2881 atgtgggatt aaatgaggag agtatagcaa tattagtcat aatgcatggt gaatctacag
     2941 catctagcat ggtgaatgta gccaatactt tactggattg taaccatgca gtggcaatta
     3001 atatgggatt agaagataga gttcaggata ttttagtaca agctgtagaa atagccaata
     3061 aaattgataa aggaaaggga attttaattt taactgatat ggggtctatt ttaacatttg
     3121 ctaaagttat tcgtgatgct acaggaaaag aagtaaaagc agtagatatg gtaagtacac
     3181 ctattgtaat agaagcaact agaaaggctc taactccaga aatgacatta gagaaattat
     3241 attttaatat tatagaatct ataaagaaac attatggaga tatggaagtt acatatgctg
     3301 aaaaagataa tggtggtaga tattttgata gactactaat tgataatatt agtaaaactt
     3361 tgactttttt aaatggggaa aaggcttatt ttatattaaa agaagtaatt aatagaatta
     3421 gtgaacacta ttctttagta attcaagatg aacttttagt aaagtttata tttcattgtt
     3481 catgtatgat tgaaagagta ataataaaag agtctttagt ttataaatca tatgaagaaa
     3541 gaattagtag aaataaagaa ttatatttag ttataaaaga aagttttaag ctagtagaag
     3601 agacattcga tataattatt tcagatatgg aatatgcaaa tatattagat atatttgaat
     3661 cacaatatga tacagataaa ttcaaaagtt gatacaaaat ttaaaaatag ccaaaaggct
     3721 atcttttttt tacttttttt gatacagatt tgatacaggt tgaaaaaatc ttttgataca
     3781 tatcgaaata ataagttttt aaaaaaaatt gagtaaaaag ttttgattaa atcctgtaaa
     3841 atagccattt attattgata cacataagtt ggcacggcaa ttgcttatat aaaaagtgac
     3901 aagaaaagtg aggtgaaatt ggtgatagga ataatagtta tgactcatgg gagttttagt
     3961 gaagaaatta taaaaagctg tgaacttatt gcaggaccag cagaaagaac agcagcaatt
     4021 aaactaaata ggaatgataa tattgaagac ttaaataaaa attttgtaga aaagttaaat
     4081 gaattagatg aaggtgacgg agttttagta ttagctgacc tattaggagg ttcgccaagt
     4141 aatgttgcaa gtttaaacct taaaaaaggt ggcaagtttc atgcacttac tggagtaaat
     4201 cttccaatgc tacttgaagc tttaattaat agagagggaa aaagtttaga agagttagca
     4261 gaagcatgta ttgaagcagg acaaactggt ataaacaata ttaataaagt tcttagctca
     4321 atgtaataga aaaaggagtt tgattaaaaa tgtctttagt aaaatattgc agatgtgatg
     4381 atagattaat acatggtcaa gtgatatata aatgggttaa gcatctaggt gtaaaaaaga
     4441 tagtagtagt agatgatgaa acaaccaatg atgttattgc taaaggtttg ataaaaatgg
     4501 cagcaccaaa gaatattgat ttatcaatat taactgtaag tgaatcaagg agatattttt
     4561 ataataatca agctgatgat aacgtttttg tattaattaa aaatttagat actgcaaata
     4621 gaatgataga agaagggatt aatatcaaaa aacttattgt tggaagaata cctacaggaa
     4681 taggaaaaaa gaaaatatct caaaatgtat acattaataa aaaagagttt cttttaatag
     4741 atgaatttat taaaaagaat attaatgtat caattcaaat ggtacctgat gaagaagaag
     4801 tagaattaaa ccaaaatatt aatcgctata aaggagagtt tatttagcaa tgaataaata
     4861 taaggtaatt atactgtgcc atggaacttg gggaaaagtc ttagtagaag aaacaaataa
     4921 aaactttgga ttgtcaaatc aatatgaagt tttatcacta agttctgaaa aagatgtttc
     4981 tgtatttatg aaagaggttg aagaagtagt agataaagaa gatgtgaaaa ttataatatc
     5041 agatttatat ggaggatcta catcaagtgt tgcaatagct gttgctataa gaagaggaat
     5101 agatgcaata aatggactta gcttacagac aattttaatc gtagatgaag aattaagcaa
     5161 agaagataaa ttacatacat taccagaaag aatcgtcaaa aaaaataata acctttgtgt
     5221 ggatttaatt aaagaattta aaaaaatata aattatgagg tgaatataat ggcaaaaata
     5281 acattagtaa gagtagacca cagattaatt catgggcaag ttataacaaa atgggtaaaa
     5341 atcgctcaag ctcaaaaaat aataatagtt gatgacttct taggtcaaga tgaatttatg
     5401 gctgacatat ataaaatggc agcaccatca ggagtagaag tagttatttt aacagcagaa
     5461 gatgcgggac aagcattcca aaacaacact ttaggagata aaaatatatt tattctattt
     5521 aaaaatgttg atatggcaaa taaggcttat aaagctggac ttaaatatga aaagattcaa
     5581 ttaggaggta ttccaaatga agcaggaaag aaaatggtgt ttacagctgt ttcattagga
     5641 aatgaggatg tagaacaact taatgaactt aatgaaaatg gggttgaaat agtcctacaa
     5701 gttataccag aggaatcatc tatgacatat gaaaatgcgt taaagaaatt taaataaaaa
     5761 atataaatta ggaggaatta taaatggaat ctgttttgat gttggcaatt gtaacaggat
     5821 tatggtattg gtttgcagca ggtcttgcag ggtataccct tttctcaaca ctaaagtctc
     5881 ctttatttat aggttttagc cttggattac tttggggtga tgtaacaact ggtatgattg
     5941 ttggtgcaag tatagaaatg gtttatctag gaatggtcgc agcaggggga aatattccat
     6001 cagataaatg tctagctgct cttattgcaa taccagtagc acttcaaact ggtgttaatg
     6061 cagaagttgc agtatctatt gcggtacctt taggtgttat aggagtatta gttaataact
     6121 taagaagaac tggtaatgct gtattggttc ataaggcaga taagtatgct gaagaaggta
     6181 atacaaaagg catctggaga tgtgcaacac tttattcttt aatatttggg tttgttttaa
     6241 gatttccaat agtttttgta tgtaactttt ttggagcaga tttagttcaa tcattattag
     6301 atgttatacc acaatggtta atgaatggat taacagtaat gggcggtata ttacctgcat
     6361 taggttttgc aacaacaata tttactatag gtaaaaataa attcttacca atgtttatta
     6421 taggattttt tatggttcaa tattttgaaa tatcaattac tgcagctgca atatttggtg
     6481 tttgtatagc tcttttaatt acctttatga aagaagacaa aagggtaggt gaagtataat
     6541 gcaagaaata aaaaataaag aagttaaaaa tggacaaggt ccaactgaag ttaataagac
     6601 aagagtactc acaaagaaag atgtaacaaa aacataccta agatggtggt ggacagcaga
     6661 gttatctaat tcttttgaaa gaatgcaagc attagcagtt tgtgcaagtt tcactccggc
     6721 tttagaaaag ttatataaga aaaaagaaga tttagtagat gcattaaaga gacacttaca
     6781 attttttaat actcaagcta tatggggagg attaattcat ggtacagttt tagctatgga
     6841 agaagagaaa gctactgaag gaaaaatccc aggagaagtt atttcaggtg ttaagaatgg
     6901 tcttatggga cctttggctg gaattggaga tactttagat tttggtacat ttcaaacaat
     6961 attcttagct ttaggtgctt catttggagc agaaggaagt gttataggtg catttttccc
     7021 aataatgttt agtatattac tattttgcga aggttattac ttatttcatt taggatattc
     7081 tttaggtaga gattcaatta agaaaattct atcaggtggt attgtcaata agataattga
     7141 tggtgcttca attctaggaa tgtttatgat gggagcatta tctgcaacta cagttaagct
     7201 ttcaactccg ctatcatttg atattggtgg taaagcaatt gttgttcaag atacattaaa
     7261 tatgattgct ccaggtttat taccacttgg tgttgtattc ttcgtatatt ggggaatgaa
     7321 atacaagaag tggacaataa ctaagttatt agtaatttta gttgtattag cattggtagg
     7381 atcattcatt ggaatattct aattcacagt gattaaaata tagaatttaa ttttaggagg
     7441 agaaagaaat gtcagaaaaa atgtatacag aaaaggaata tttagaagga attagaggag
     7501 caacaggaga aagagcagta tggttctatc ttcttatgaa agaagctgaa aaattaggag
     7561 ctaatccaga tgatatatgt aaagaagcaa tatatggatt tggtaaaatg agaggtcaaa
     7621 aatataacgt agcagatact ccaggaaaaa tggcagaaat gttatataac agtaaaggac
     7681 aaaaagtgtt tgaaatggaa ttagtagaaa atacagatga gaatggcgtt ttaaaattcc
     7741 atcactgtcc attagatgct gcttggaaag aatatggatt aactaaagaa gaaagaaaag
     7801 aaatttgtag attagcttgt tatggggatt atggaagagt tgactgtgca caaggtgtta
     7861 aattagattt tgctcaaaaa tgtgctcatg atgatgaagt ttgtgaatta gtatttacaa
     7921 aaaaataatt tttaatgcta aaagcctgtt ctttaaggac aggctttaaa aagatagaaa
     7981 gtaggttgat ttatggatat aagcagaagt gtagataata gtttaaatag aaccatagaa
     8041 tttctaaaag aattgataaa aattgattca caacaaggtg aacctatttc acaatgtcct
     8101 tttggtatag gacctaaaaa atctttagat aaaactttag attactgtgc tagtttaggt
     8161 tttagtgtta aaaatattga taattatatt ggatatgcag aaattggaga gggagaggaa
     8221 ttaataggga ttccaatgca tttagatata gttccaccag gagaggggtg gagtgtagac
     8281 ccattttcgg gagcagtaat tgacaatatt atttatggaa gaggtgtcat agataataag
     8341 ggtgctgtat ctatgcttat acatgtattg aaaaacatag aggatatgta tcctacaatt
     8401 aataaaagaa taagattaat ttttggtaca aatgaggaga cagatatgaa atgtatcaaa
     8461 tattacttag ataaaggtga agaaattcca agtatgggat ttactccaga tgctatgtat
     8521 ccagtggtta atggagaaaa aggaagggtt catataagga tagaaaaaga aattaaaatt
     8581 gacaaaagta aaccttacat aatagtaagg ggaggaacta aagaaaatgt tgttccatct
     8641 cattgtactg caaaaattat taatggaatt atttcagagt taactactaa aggagtagct
     8701 gtacatgcaa gtaatcctga aaagggagaa aatgctatat ctaaaatggt aataaagata
     8761 gttgaggata atatggattt tcagcataga gaagatatag aattagtttc aaaatacctt
     8821 tgtagtgatt attatggaga tgcattgggg attaatcaat atgatgaggt attcaaaaac
     8881 actaccttaa atttaggaat attaaaagta aatgaggaaa aaatcgtatg tgagttagat
     8941 ataaggtatg gtaaaaatat agttttaaat aacataatag atagattcaa aaaggttttt
     9001 tgtaatggtt ggaaaataga ggttattgct cataaagact tacattatgt ggatgagagt
     9061 aatttagtac ttaaaaaatt attagaagcc tatgaagaag taacagatga aaatggatat
     9121 acaattgcta tgggtggtgg cacatatgca agttggttta aagatatggt ggcgtttgga
     9181 cctaagttct tagcgtataa aactggtggt catggagtag atgaaagagt accaataaat
     9241 catatacgaa agaatatgga gatatatact ttggctttaa taaaactatt agaattgtaa
     9301 aagaagaaga gactttatgt gcaaatttac agatatctta aaaagagaga taaaacgagt
     9361 tcaactttat ttaaatgttc aacaccatca aatggggctg tctcaaaata gagataagcc
     9421 tcttgcttat tattgaaatg atgaaaatat attttacttc atacaaaaaa gagtgcctta
     9481 tgaagtaaaa agttaatttt gagacaccct catttgatga tgttgaagag aaaataagta
     9541 tgaaattatt aaaaaaagat gattttataa aagttaaggt tgaaaataaa agttaattga
     9601 atggaattag ataaatggag aaggctgtat actatctaat aaaataacaa aagagtgtta
     9661 taaaactggt tatatgatta gagaaaagtc tattgatact tatccagata gtggacgggg
     9721 atttatgact tgggatgaaa atggagaata ataaaaatta tagtttatac aatttaataa
     9781 gatatatgta caagcagtta atctaaatga ttgactgctt ttcttttata gatttttata
     9841 taatagacaa ttactaatac atgatagttg cctgttataa ttagaggaat agatacgaat
     9901 aataacttta taaaagaatt aaatggaaaa ttgaagagtt atattcagga ttttaaaaag
     9961 aatatgaaat gagaaatgaa aataaggtgt ttatattaaa agaggtttta cacaaaatac
    10021 ttaaaaacgt gataaataaa aactgtattt agataaatta actactagtt ttatatataa
    10081 tatggatttt gtttacaaag tttacatatt tcacaaaata tttttaaaat atatttaaaa
    10141 atatatttta tatacttgtt cgtttgtttc tctgtggttg attttttcgt caaaagtcaa
    10201 cttcaaatcg cttgttagct ttacatgttt aaggatataa ttatacataa ggagggattg
    10261 acatgaatga attaaacatc gcaaaaacgc tgattttaaa gcgtaaagaa aaaggaatta
    10321 cacaagatga acttgcaaat tatataggcg tttctaaagc ttctgtatct aaatgggaaa
    10381 ctggacaaag ctatcctgac ataacctttt taccgcaact cgcgacatat ttcaacatta
    10441 ccgttgatga gttaatatgt tatgaacctc aaatgatgaa ggaagatatt aataaactgt
    10501 ataataaact gtgcaaagac tttacggtta aaccgtttga tgaagtcatg gatgaaataa
    10561 gagaaatcat aaaaaaatat tattcatgtt ttcctttgat ttttcggatg ggtcttttaa
    10621 tagttaatca ctatgatatt gtagatgaaa aaaagcgtga actattaatt agtgaagcat
    10681 tagaaatatt tattcgtata caggaaactt gtaatgacat agatatttgc cgtcaagcaa
    10741 aaagtatgga ggcaacttgt tatatattgt taaatcaacc catacaagtg attgatttat
    10801 tgcaaaacag caattttccc atgataaatg aatctatact tcttgcacag gggcaaatga
    10861 tgaatggtca aatggatgaa gcaagagaaa catttcaact tggtgcatat cagaacctta
    10921 tatcattagt ccaaaatcta gtgggtattt tgcaaaatgc agataaatta caaatgaagg
    10981 aaatagaaag acgtattcta gcaatttcag atatatttga gcttgataca ttatctcctg
    11041 ctattatgct ttcttcatat ttaacacaga cacaaattaa tttaatacat ggggataatg
    11101 aaggagctat taaatcatta cgaaaatatg tagatttagc aacacgtgat atatacccaa
    11161 ttataataca tggggatgac ttttttaata aacttgacag atggatttct gaaattggaa
    11221 caggtattac acgtgatgat acaatcgtaa aagcaggtat tgttgctgct attaaaaata
    11281 atccaatgtt ttctttatta agtgaaaaca aagaatacaa atttcttata gaaaaattat
    11341 ctttattgga ggaataagat tatggaaaat ttgatggaat atttaccact tttgattcct
    11401 gttattattt tagatttaat acttataatt actgcacttg ttcatgtatt gagacatcca
    11461 aattataaaa ttggaaataa ggcaatatgg attattgtag tactgtttat tagtctaata
    11521 ggaccaatct tgtattttac aataggaaga ggtgaagaat gatgaatatt gtctcaataa
    11581 atggattatc aaaaggtttt ggtaatcgaa agataataga taatctaaat tttactgtac
    11641 cagaagggtc agtctttggg tttgtaggta agaatggtgc aggtaagact acaacaatga
    11701 aaatggtact tgggttactt gaaccagata gtggaactat agatgtttgt ggtgagaaag
    11761 tgacatatgg aagaacaagt tctaatcgtc atgtaggtta tctgcctgac gttccagagt
    11821 tttacaacta tatgagacca cttgaatatc tttctctttg tggtgaaatt acggggcttt
    11881 caaaaaaaga aataaagata aggagtgaag agttgttatc acttgtgggg cttggcaatg
    11941 aaaagagacg aataggtggg ttttctcgtg gaatgaagca acgacttggt atagctcaag
    12001 ctttgctttc acgtcccaaa ttacttattt gtgatgaacc aacaagtgca cttgaccctg
    12061 ttggtcgaaa agaaatatta gatattatgc ttaaaatcaa agactcaaca actgtaatat
    12121 tttcaacaca tatactatca gatgttgaaa gaatctgtga ccatgttgct atactaaaca
    12181 aaggaagcat tgctcttagc ggtacacttt cagaaataaa aagtatgcac ggaaaggata
    12241 gacttttact ggagtttgca agtaataatg aaattcaaaa gtttaagtct agtggtggca
    12301 ttaaatcctt actaaaagat tcagaagaaa ctaatatgga aattgttttg catggtaaag
    12361 atataaaagc aatacaaaaa acagttatat ctacactcgc agaaatgaat ctttgtccag
    12421 taaagatgga actaatagaa ttgtcacttg aaaatttgtt tttggaggta gtaaagtgag
    12481 agaatacata gcatttacaa aaaaagagtt taaggagaac ataagaaatt ataaattact
    12541 tagtttgact attttatttt tagtatttgg aataatgagt cctctttctg caaaatttat
    12601 gccagacttg attgctcatt ttgctccaac tttaaaagtt actactgcac caactgcttt
    12661 agattcttgg acacagtttt ctggaaatat ttctggtctt ggaacgagtt taactctaat
    12721 tgttttttgc aatattttat caaacgaata ttctaaagga acactcgtta ttatgttgac
    12781 taaagggtta tcacgttcat ctgtagtatt gtctaaattt tctattgcag taattattat
    12841 gacaattggt ttttggttga gctttttatg tacttatgga tatacaatgt atttttggcc
    12901 aactgcaaat cttaatcata ttatattttc agcatttaac ttatggttaa ttagtattat
    12961 gtatatttcc atattaattc ttgggtgtgt actatttaga ccagcatttg caagtgtgtt
    13021 acttgtatta gcagcaactg ctattttgag tttgatttct attcctaaac agattgcacc
    13081 ttatacgcct aatttcatat tatcaaaaaa tatagattta gtttcaggta aagtgacacc
    13141 tccagaattt attattccaa tcattgtaac aattgttatt tcgatagtat gtctgttatt
    13201 agctgttgtt ttgtttaata aaaaagcagt ttaaggatat ttttattata aatacaaata
    13261 gtgctgtatt gtgggaaaat gtgtttagta ttgtagaaga atatatttaa gtaaaaaaga
    13321 ggctgtctca agatagagaa ataagcctct tttttatttt agtcctcctc actatacttt
    13381 ataataatta agttattacc ttaaggaact atctaaaaaa agagatatag attataatct
    13441 aatgcttatc agttatttga ggtgtttagt atatagagtc taaagtagtg aaggactaaa
    13501 ataatattgt tttcattaaa taaagataag aatctttaat tgtggtaaaa tatactaaaa
    13561 aatcatttta aaagtgataa aattatttta agtaaatatt ttaaaggggt gtagatatgg
    13621 aaaagtcaaa agtatatttt tgtgatttat actcaaattc gcaaaataaa aacgtaccaa
    13681 acaatgtaag aagattattt gatgaagcag gattcaaaga tttaatagaa aagaatgacc
    13741 aagtcgcaat taaacttcac tttggagaaa agggaaatac tacatatatg agtcctgtgg
    13801 cagttagaca agtggttgat aaggttaaag actgcgaagg aaagccattt ttaacagata
    13861 caaatacact gtatacaggg agtagaacaa attctgtaga ccatcttaca actgctatag
    13921 aaaatggatt tgcttatgca gttgtaaatg caccagtaat aattgcagat ggattatata
    13981 gtagaaatta tgagaatgta aaaatagaca aaaaacattt tgaaagtgta aaaataggtg
    14041 gagaaattta taattcttct gcaatgatag taatgagtca ttttaaaggt catgaagcag
    14101 caggttttgg aggagcatta aaaaacttag ctatgggatg tgcaagtgca gcaggaaaac
    14161 aaatgcaaca ttctgatgtt actccagtag taaaggaaaa gaagtgtgta ggttgtggaa
    14221 agtgtgttaa ttcttgtcct acaaaagcta taagtatagt ggataaaaaa gcagttatag
    14281 attctgatgt atgttatgga tgtggagaat gtccaactgt ctgtccaact agagcagtaa
    14341 ctatacaatg ggaaagtgac tcagatgtgt ttgtcgaaaa gatggcagaa tacgcttatg
    14401 gagcagtatc aaataaaaaa gacaaggtag ggtatataac ttttgttatg aatgtaactc
    14461 cactttgtga ttgtgtacct tggtcaggta gaccaattgc ccatgatata ggaatattag
    14521 catcaacaga ccctgtagct attgaacaag catgctatga tttgatttgt aaggaaatgg
    14581 gtcatgatgt tttcaaacat gaacatcctc atgtaaatgg aactagaata atagactatg
    14641 catgtgaaat gggtatggga agtaaagaat atgaattaat aaaattataa gaatagtagc
    14701 acttaaatgc atataattat tgtaagagaa atctaaaagt atcaaaggag tatgcattta
    14761 tgaaaattta ctatgagaag gaaaacagca agaaggctaa tgtaaacaat attccaagtg
    14821 tatttgcgtt taattttcta agaaactttt tgactagcaa agagtatgag gaaactagaa
    14881 aagaatattt tataaataat ctaacaaaaa gtcaggttaa tcaagccatg aaggatttaa
    14941 aatggctatt tagagaatat gaaggcttag aggttattac aatggaaagc ttggatggag
    15001 ttaagacaag gatagtttta taaaccagta agaattatat tctaataaaa aatactgctt
    15061 taataataat atgtataatc tatatactaa tattattttg aagcagtatt tttttgtgta
    15121 tagtaaactt gtgtctaaaa taaagttgac caataaatgt tatatatgca atactatata
    15181 taataagtaa actacataaa aatattaagt tgacaaatag gaggatatat ggaaaaatac
    15241 ataataaaat taaaaaataa agtattgaga gaaaaagaaa taagttatga agaagctctt
    15301 aatttaataa gccttgatac aaataataaa aacgattttg atattctatt aaaatctgca
    15361 aatgaaataa gagaatattt tatgggaaga aaagcagatt tatgtacgat aatgaatgct
    15421 aaatctggca aatgtagtga agactgtaaa ttttgtgctc aatcatctca ttataaaact
    15481 ggtgtagaag aatattcatt attagattac aatgaaatct taaatagagc taaagagatg
    15541 gagagtaaag gagtgcatag attctcattg gttacaagtg gtaaaggtat gtcaggaaag
    15601 gagtttaata atattttaaa tatctatgaa ggattgaggg aaaatactaa tttaaaatta
    15661 tgtgcatctt taggtattat agattatgag caagctaaaa tgttgaagtc agcaggtgtg
    15721 actacatatc accacaatgt tgagacgtgt agagataatt ttcataatat atgtacaaca
    15781 cacacatata aagataggat aaaaactata aaagatgcta aaaaagctgg gctagatgta
    15841 tgtgtaggcg gtataattgg aatgaatgag agtgaagaac agagactaaa aatggttttt
    15901 gaaatacgag aattaaatgt aaaatcattt ccaataaaca ttttaaatcc tattaagaat
    15961 acgccaatgg aaaattatga tgtattagaa ccaatggaaa tactaaaaac aacagcagta
    16021 tttaggttta taattcctaa tgtgtacata aggtatgctg gtggaaggct atcattaaag
    16081 ggatatgaca aagttggatt taatggggga gtaaattctg caattgttgg tgattatttg
    16141 acaactgttg gaagtgggat tgaaaatgat aaaaaaatga ttatagagca aggatttgaa
    16201 ctttaataaa tactacttaa attaattaat atacttttag ataattataa aagtatatta
    16261 attttttttg cagattaatt taaatattaa aattgaatta taagttgcaa tattttgaaa
    16321 aaagggaaaa atatcaaaat ttatataaaa tggttgcaaa tgggaaaagg atgtgatagt
    16381 atctaggtaa ccggttaagt aaaacggttt cctaaatttt gggggtgaac ttcttgagta
    16441 taactataaa agaaattggc gaattggctg gtgtttctaa aacaactgtg tcaaaagtca
    16501 ttaataataa agatgaaaat ataagtcagg caacaagaga aaaaattttg aaaataatga
    16561 aggaaaaaaa ttatgtacca aataaattag cacaaagttt agtaactaaa aaaactaata
    16621 ctatagggct tcttatacca gatatacgaa atccattctt tacagatgta tcaagaggtg
    16681 tagaagacaa agctaatgaa gaaggctaca atataatttt atgtaataca gatgaagatg
    16741 ctaaaaaaga atatgaagga ataagaacac tatcagagag gatgatagat ggaattatat
    16801 ttgcagcatc ttcaaataca aactggaaag aagcaaatta taaagatata aaaataccaa
    16861 ctgtcttgat tgataagaag ataagtatga acaaagaaac cttaaaagga attgttaaaa
    16921 taaataactt tgaaggggcc tatatagcta caaaacattt attagatatt ggaaataaga
    16981 aaataatata cctaagtggt ccacttcaaa atgaaatagc agtagataga ttagaaggat
    17041 ataaaaaggc tctaatcgag tgtaatttaa gctacaattc tgcttatgta tttgaaggaa
    17101 aatataagat tgaatgggga caagaattta taaaaaattt agaaaagata gattttgatg
    17161 caatattttg tgcaaatgat ttgattgcaa taggtgtcat aagaggtctt aaagaaagag
    17221 ggttaagtat accaaatgat gtaagtgtcg tgggatttga tgatattcaa acatcaagtc
    17281 taataagccc ttctcttacc acagtaaaac agccgtctta tgatatagga tataaagcca
    17341 gtgaaatatt gataaattgt ttaagaggag ataaaaaaga atcatttgat gaattgattt
    17401 tcaaaccaga attagtcata agagattcaa caaaagaaag tgaataacag cacgagagac
    17461 ataaatagat atgtaaagga gtaatgtaat gggaaacata gttgtcatag gaagtgtaaa
    17521 catggacatg gtatgttctg tagataaaag accagaaaaa ggagaaacag tattaggtaa
    17581 tagttttttt acatcacctg gagggaaagg ggctaatcaa gctatctcag cttctaaact
    17641 aggagcaaat gtaaaaatga tatcatgcat aggggaagat ggcttaggag aggagttaat
    17701 aagaaatttt agaacgaata aagttgatta tagtttagta tccagaaata atcacaaaag
    17761 ttctggtgtt gctgttataa cattatgtga aaatgataat agtattgttg ttgtaccagg
    17821 gacgaatgag ctagtagata tagaattaat taaaaagaat gaagaagaga taaagaatgc
    17881 agatatagta ttgctacaat tagagattcc attaaaaaca ataaattatg tagtgaattt
    17941 ctgttttgaa aataggatta aggttttatt aaatccagca ccagcagtaa aactaaatga
    18001 agatataata gaaaaagtaa cttacttaac accaaatgaa catgaatata agatagtttt
    18061 tgacacaaat gaagggatag aagaagtatt aaaaaaatat ccaaataaac ttgtaataac
    18121 agaaggaaaa aatggagcta gattttatga tggtgaggaa atcaagcatg tatcttgtat
    18181 aagtgttgat gttcaagata ccacaggagc aggagataca tttaatggag cattggcagt
    18241 ggctataaca gaagggaaaa aattatatac agcagtagaa tatgcagtag tagtatcagg
    18301 tctttctgta actaaactag gtgcacaatc tggtatgcct tataaagaag atgttgaaaa
    18361 atatttaaat aataaataaa aatctaattt gttcaaattt aaaactatta aaaatggagg
    18421 ttaattatga gagtgagaaa aattttatct ttaggaattg ctggaatact agcaatagga
    18481 atgttaacag ggtgttcaat ggaaggacca agtaaatcag ataataaagg tggttcagac
    18541 aagaaagatt taactattgg agtatctaca ataactcttc aacatcaatt ttttatagat
    18601 attgatgagg gaataaaaga aaaagctaag gaattaggtg tgaaagttat agtaaatgac
    18661 ccagaccaag atgtagctaa gcaaacatca gcaatagaag attttataca acaaaatgta
    18721 gatggaatga tagtacttgg aactgataat tcggctatag taccagcagt agaaggagca
    18781 tttgaaaaaa tgccagtagt tacagtagat gctgtattaa atactgaaaa tattacaagt
    18841 tatgtaggaa cagttagtta tgatgctggt aaaaaattag gggaatacac taaaaaatac
    18901 atagatgaaa agttaggtgg aaagtcagaa atagcaatag tgacagattt aaaatctcaa
    18961 atacaaatgc agagaataga tggatttaaa gatgcgttaa aaggttcagc aaatgttaag
    19021 atattaaatt cacaaccagg atatgacaga gaagaatctc ttaatacagt agaaaactta
    19081 attcaatcta atccagatgt agatataata tatgcaacag ctgaaaatag tgtactagga
    19141 gctaaagctg cacttgaatc tgcaaaaaat aaggatgtta agattgtagg atttgactta
    19201 actgaagaag catcaagtgg aataacagat ggaactattc ttgctatgat tcaacaacaa
    19261 cctaaagaga tgggacgttt agctgtagaa gcagtagtaa aagctataaa aggggaaaag
    19321 gtagaaaaga atataccagt accagcttta ctttatgata aggaaaatat aaaagacttt
    19381 aagaattagt aaaataaaat gagattattt gaaagaaatc ctatttaaaa aggagtgtca
    19441 ttatgagtaa tataattctg aagttaagta atattgctaa agaatttcct ggtgtcagag
    19501 cattagataa tgttaatttt gagttatttc atggcgaagt tcatgcacta ctgggtgaaa
    19561 atggtgctgg taaatcaaca atgataaaga ttttaactgg tgcacattcg aaaacttctg
    19621 gaaaatttat ttttgaaggc aaagaaatag agaatatatc cccagatatc tctaaaaaga
    19681 taggtataaa tgccatatat caagaactaa cagtttttga cgaattaaca gtagcacaaa
    19741 atatttttat gggaaaagaa ataaatggca aagtcttaac caatgacaaa aaaatgaatg
    19801 aagaggctaa aaagattttc gataatatgg gaatagatat aaatccaaat agtttagtca
    19861 aagagcttag tatagctcaa aaacaaatgg tagaaatagc aagagtttta tcatcagaaa
    19921 ctaaagtatt aataatggat gaacctactt cttcaataag taaaaaagag actgaaatac
    19981 tttttagact tataaatgat ttaaaagaga gtggagttag tataatatat atatcccata
    20041 ggatggaaga actctttgag atttgtgaca gaataactat aatgcgagat gggaaaacga
    20101 tttcgacttt gaataccaaa gatgtatcgt ctgaggaaga attagttaat ttaatgatag
    20161 atagaaagct agaccaattt ttcccaaaaa gaaaagtaga aataaaagaa gaaattatgc
    20221 gagtggaaaa tctaactaag aacaatgttt ttaatgatat tagctttaat ataagaaaag
    20281 gtgaaatatt gggaataggt ggactagttg gaagtaagag aagtgaaata gtagaagcta
    20341 tatttggact tagaacatat gattctggga aaatatattt aaacaatgaa gaagtaaagt
    20401 ttaaaactcc atcagatgca atagaaaatg gactgggatt aataacagaa gatagaaaag
    20461 gtactggatt gtttttacaa atgagtgtca aagaaaacac aactatggct gggttaaaaa
    20521 agatatctaa gtttaaatca attatagata gaaaaaagga aaaagagatt ttagaaaaat
    20581 acatagaagc tttaaagata aaaacaccac atatgaatca agttatacaa agtttaagtg
    20641 gtggaaacca acaaaaagct ataatagcaa gatggctttt attacaacca gatatattga
    20701 ttatggatga accaaccaga ggtatagatg taaatgctaa ggcagagata tacaatctaa
    20761 tgggagattt agtggagagt ggtgtaagta taataatgat atcttctgaa ataccagaat
    20821 taatatcaat gagtgacaga ataatggtta tgagagaagg tcatataagt ggatttttag
    20881 aaggtgaaga aatggttgaa aataatgtat taaaattggc tttcggaggt aaaattaatg
    20941 agttcaataa ctaagcataa agaagaaaaa tcttctccat tattgacaaa attaacaagt
    21001 gtatttagag accaagggag tgcagctgta ggacttgtaa taatttttat aataatgagt
    21061 gtagcttcat ctaacttttt aactttagat aatttaatta atgttggaag acaaatatca
    21121 ataaatgcaa tacttgcagt aggtatgaca tttgtaataa ttacaggagg aatagattta
    21181 agtgtaggag cagtaattgc tttagtaggt acattttggg ctacaacagt agtgaattat
    21241 aatgcaccta tatgggtagg tatgatactt gcattagcaa tagggacaat attaggagtc
    21301 ataaaaggtg caattatttc aacacaaaaa ctacctccat tcattgtaac tttagccatg
    21361 ttaacgataa taagtggggc aagctttgta tttacaggag gaagacctat atcagtaaat
    21421 acagatgcat ttaagatgct cggtagagga tatattggac caataccaat accagttata
    21481 attatgatta tagttgtaat agcaggacat tttctattaa aaagaactaa ttttggacgt
    21541 catgtacatg cagtaggtgg aaatgaagag gccgctagat tatgtggagt aaaagtaaat
    21601 aaagttatag taaaagtata cgcactagct ggactactaa cagcattagc tgggataata
    21661 ctatcatcac gtttggcatc aggttcacca actgttggag atggagcaga attggatgct
    21721 atagcagccg ttgtgcttgg tggtactaat atgatgggtg gttctggttc tatagtaggt
    21781 acatgtatag gtgtcggaat aataggaata ttaggaaatg gattaaactt attaagtgta
    21841 tcttcatata atcaaatgat tataaaaggt ttggtaatgt tatttgctat atggataaat
    21901 aatataaaat taaaaaaatc agctaaatct aaatagtaat taaattttag cttataaact
    21961 ataaaaatta ttaagttttt gtatatattt ttatacttta atttgcatac atctttatac
    22021 attgaatggg aatatgctaa gtgaaaaagt ttactatggc ttaaatagat gagattagac
    22081 ttgaaatttt aaatgtaaaa ataaatctta ggaggaaata tgaaaaaaat tctcttagat
    22141 acattaaata gtaaaaaaca agaatacata gattatttaa aagaacttgt aagtataaag
    22201 actgaagatg ttggtcatgg aatactaggt ggatttgaaa aagaaggaca ggaatatatt
    22261 gaaaaacttg caaattacat aggttttagt gtagatagac aagaaatgag cgaagaatta
    22321 attaaaaaag caaaaaatat atataaagaa ggaaatctag gtcacaatta tcaagataga
    22381 tataatttaa tttgtaagta tagtgatgat ttacctggta agacaattgt atttaatggt
    22441 catgtagaca ctatgccacc aggtgatata agtaagtgga aatataatcc atatcgtgct
    22501 acagaagata atggaaaact ttatggtctt ggaactgctg atatgaaatc tggacttata
    22561 gcatcaatat tagctgtaaa gcttataaaa gatagtggtc taaatgtacc tggtaatgta
    22621 aaaataatgt cagtagtaga tgaagaaggt ggcggaaatg gtaccataaa tgcagttatg
    22681 aatggtattg gtggagattg ttgcataatt tgtgaaccat cagaacaaaa cttaatagtt
    22741 gcacatatgg gatttgtatt ctttgaagtt gaggttaaag gtgtgtctct tcactgtggt
    22801 agtaagtggg agggtgtaaa tgcaattgag aaggctatgt tgttgcttca agatataaaa
    22861 gagttggaac ataactggct tatgatatat aagcatccac tattaccttc acctacaata
    22921 aatttaggtg taataaatgg tggaacagca ggttctactg tgccagataa gtgtgtattt
    22981 aatttatgtg tacacttctt gccaaatata atgagttatg aacaagttgt aaatgatgta
    23041 acaaatgtca taatgacaag ggctaatgga gatttatggc ttaaagataa taaaccaaat
    23101 ataaacatat atcaatcagg gttaggtttt cagatggaca aggattctga ttttgtagtg
    23161 aatgcacata aaatactaga agaaacttta ggaaaaaaat tagagataaa aggttcaaca
    23221 gctggcaatg atgcgagatt aatgaaaaat ttagctgaaa taccaacact tatattaggg
    23281 ccaggttcaa tagaacaatg tcattcaatt gatgaatatg ttgaaattaa ggagtattta
    23341 gatagtatac ttatgtatgc aagtctaata ttaaacttat aaaagtagga ggaatatata
    23401 aatgaaaaaa gtattaatag taggggaatc ttgggtaaaa aatataactc atataaaagg
    23461 atttgatacg tttgttacaa ctcattatga agaagctgta aagtggttga aagaagcaat
    23521 agaatctgga ggatatgaga cagttcatat gcctgcacat gtagcagcag atagttttcc
    23581 gtataaatta gaagagttaa atgagtatga ctgtataata ttatctgata taggttctaa
    23641 tacgttctta ttatctaata gtacttttat agattgcaat agtaatccag atagacttga
    23701 actaatcaaa gagtatgtaa ataatggtgg ggcgttaatc atggtaggtg gatatatgtc
    23761 atttacagga atagatgcaa aagctagatt tggagaaact gctatcaaag atgtattacc
    23821 aataacaatg atagataaag atgatagagt tgaaaaacca gcaggaataa ttccagaagt
    23881 tattgactct gaacatccag tattaaaagg tataccaaca gaatggccaa agtttttagg
    23941 atataacaaa acagtagcta gagataattg tcctgtttta gcaactattg gaggagaccc
    24001 atttgtagct gttggcgagt ttggaaaagg aaaatctgct atctttagtt ctgactgtgc
    24061 acctcactgg ggtccaaaag aatttactga ttggaaatac tataataaat tatgggttaa
    24121 tatgcttgat tggttaacat gctaaaaatt ttataaaact tgaaaacctc ttacttgata
    24181 aaatgaaact tacaagtcaa gaggttttat tgtataaaat ggttgtatgg tagaaaatat
    24241 ttttaaatca gttaaaatta gtcattttgg ctgataatcg ataagttatt agaaacaggg
    24301 aggtttatat aattaatatg gataatttaa ataaaaagtt tttgatggaa tatatagatg
    24361 agatacaggg agaattaaga gatatatcag ataagatatg gaaaaatcca gaacttcagt
    24421 ataaagaata ctatgcttca aatttacaaa aagaatgttt aaaaaaacat ggttttagta
    24481 tagagggatt agaaggtatg gatacagcat ttgtggctag ttatggagaa ggtagaccag
    24541 ttatagcagt tttgggagaa tatgatgctt tagatggttt gtctcaaaaa gtatccacta
    24601 ctaaagaacc tattgtagat ggtggtgcag gtcatggatg tggacataac ttacttggta
    24661 caggttcaat aggagctgta attgcagtaa aggaattaat caaactaaaa aagctgaaag
    24721 ggactataaa atactatgga tgtccagcag aagaagattt atctggaaaa gtattgatga
    24781 taaaaaaagg tttttttgat ggaattgatt gtgcttttag ttggcatcca tttgatataa
    24841 atactccgat aagaatccca acacttgcta attactctgt gaaatttaga tataatggga
    24901 ttagtgctca tgcagcacaa gctccttata acggaagaag tgcacttgat gcagtagaac
    24961 ttatgaatat aggttgtaat tatttgagag aacatatatt tgataattgt agagtacact
    25021 atgtaactac taatggtgga aaaatgccaa atatagttcc tgattttgca gaagtgtggt
    25081 attacataag aggagttaaa atggagcatg taagagatgt atttggtagg attgttgata
    25141 tagcaaaagg agcagcatta atgactggta ctattatgga atatgacatt ataagtggag
    25201 tatatgacta tattccaaat acaatattaa cagatattct atcacaaaat atgaaattag
    25261 taggtgtgca aaactataat gaagatgact actattttgc agataaatta gctgagacag
    25321 tgtctataga taaaagaagt agtgtttcta gtgtattaag tggaaataag gatattacta
    25381 agatgaattt acatgatgag gttacagatg atacatttac tcataataac tgtatatcat
    25441 tatcattgga tattggagat gttagctaca taattcctac agcacaatgt tcttgttcag
    25501 tttggcctat tggtatttct gcccatacat ggcaatcttg tgccagtgca ggttctgata
    25561 tgggatttaa ggcaatgtta ttggcatcta aatctatatc atgttcaata aatgatgtaa
    25621 tgcttgatga attggttata aataaagcaa aaaaagaatt gaaggatact gtaggtagtt
    25681 ttgaatatac tccaattatt tgaagagtaa tttaatacaa gtaagattga attgtatgaa
    25741 ttaggatgaa tatataaatt aatattattt ttaacttaac tttctaatta ttttcaatct
    25801 aagatacaat aattagaata tatttttaaa gtttcctatt taaggaaaat aatttgattt
    25861 tatgtttgat aaaaggactt ataatttgta agccctttta ttatatttat tttttgttta
    25921 taattaattt tattttttag gtttagttag gttatagatt accctgaaaa ataacattta
    25981 acttattatt aaaaacatgt aagaatagtt tataaatatt ttattttcga tgttgtttat
    26041 tatatccatt ttatcgatgg atgaggaatg gctctgcctt ccctagttac agatgtagta
    26101 gggaaaccaa ttgcacaggc atcaaatcca tattcacctg ttggtactcc taaaatatca
    26161 caaaaatctt tattatcgct caatcttcct attacactaa caagttcaaa acctaatcct
    26221 aaagcagttg atttaagcca catattctgc atcacatgag ataatgactt ttgttctata
    26281 ggtggtattc cacgacgttc tgccacaata ataagataag gtgctgttcc tataccaaga
    26341 accccttttt caacttgcat ttttaaggaa gtaatgaagg attgaagggt aatgttgttc
    26401 tttgccttct tctcattgac tgatatttga gttttaataa catcaacaag aatggttttt
    26461 attttattca tttgtaaact gttatttgaa ataacaaaga aatgtctgaa atctgtttgt
    26521 tttgctactg aaagtattgc ataaggtgca agtcttccag tttcaattat ttcttcaatc
    26581 agcccttttg aaggtacttc ttttgtaaaa cttcttatgg atcttctagt tcttaatagc
    26641 atatccaaaa cttcattaac attgttttta tctaaattgt tcatttttat cctccactaa
    26701 tagtattctt aagatgttct ataatgcatc catataaagg cgaacttttc ggtcatatta
    26761 aacatttcct tcaaattaag tcgctatttc tatgaacaca atgttgatta ataatctata
    26821 tgtatattat aatatttata ttgcattatg caataaacaa taatatttaa actgttaagt
    26881 aataaacatt tactataaaa ttgttaatta aaattaaaaa aatttatatg gaatgaggaa
    26941 ataattcatg aaaaaagtat ctattgatag aagaactata cgtactaaaa aaatgattag
    27001 gtctgcatta gcagagttaa tagatgagaa aggatttaac aatatatcag ttactgattt
    27061 aactcaaagg gcagatataa atagaggaac cttctatctg cattatgttg ataagtatga
    27121 cttgttagag aggattgaaa atgaaataat acaggaaatt gaagaggaga ccaaacatct
    27181 tgattcatcc aacatgatgg agatagatac ctcaagtgaa cctcttccat ttatggtaaa
    27241 gctttttgaa tattttagaa aaaattcagt aattattaaa tctatcttgg gtcccaaagg
    27301 tgaccctact tttgaaagaa aaataaaaaa atttattgaa accaatttgt ttgagaaaca
    27361 aaaactaata aattttaaca tagatgaggc aataatttca gaagaatatt ttatacaata
    27421 tatactttca gcagacttag gtgtaattca atattggctt gaaaaaaata tgaaagagtc
    27481 ccctgaagaa atggcactga tacttgctag aatgtcgtta ctcggtccgt taagagcagt
    27541 gggaattcgt aaagattcat aaaaatagtt ttatatatat tagactttga aaatatatgt
    27601 ttaaaaacca ttttttacta ctactgttta taaattaggg gagatatctt aaaatattag
    27661 taaaaggagt gctaagtgag tgtaataact atgagataag aggtttagtt gatatagtca
    27721 aaacttcaaa agaatcaatt agaaaagtta aaatattgca attaaattta aaggagtaat
    27781 atatgaaaaa tgaaaatata agttatttgg cgttaggatt atgttttggt gttgttttgg
    27841 gttcattatt taaaaactta gctattggtt tatcctttgg attagttatt ggagtagtat
    27901 tagacagtaa gaaaaataaa taaaacttca atagtaacat ataacaatta tactattttt
    27961 gtataaaatc attggaaatc aacaatagaa aatatttgtt atttaaaaac taaaaataca
    28021 gtttaaacga cctaaaaata tattatataa ttattataac aagataagtg agagtaaggt
    28081 tatgataata gagtaatatt tttcaattat tactctattt atatttattt agttatacta
    28141 tagtttatat tgttatttta ttttcatatg cagtataggg aatggattac cttgttcatc
    28201 gaactcagat tttttaaaga ctttaaatcc catatgttta taaaagccta atgcttgttg
    28261 attttgctca ttcacatcta cataatttac atttaatact tctattgcat attctacaag
    28321 tctttttcca attccatttc ctatactata attacttaca aataacattt caattttaaa
    28381 atcatgtatt cccataaaag cttttataat accttttttt gtctcttaca cataaaaaat
    28441 tactaacata tttagcacat tctttaactt gaggctttat tgatattata ttttcttcac
    28501 ttaaaaagtc atgtgttgct cttactgatg attcccgtgt atctagtatt tctttcatat
    28561 ctttattgtt aataatattt aaattttcaa tttttatcat ttaataattc ctcttaagta
    28621 agtatgttac ttaatattat atgttaaata tgatttaaaa aggttataag aatatttttg
    28681 tattaaatat aatcaaataa atatatttat ttgtcataaa ttaaatgtcc actaaaatag
    28741 aaaaaataag aagaaatagg taataaatga tagcttatag caaaataaag atgtaagtat
    28801 aacaatagat gagattggaa ttaagtcact atacctaaca gaacattctt aggcgaatat
    28861 agaagactta aaaaagaaaa gagaagtaga caagaattta ttaatgatta catataaaat
    28921 aaatgaatta taattttatt aatgatataa taataattaa caaaaaataa aagaggaacg
    28981 agttaatgtt tgatggcata cactcatttt ctaaccaata aaacaataga ttcaattaag
    29041 gttactaaag tctaatcaac acataaacat ataggataaa tacatctttt taatatatta
    29101 attatgttag acttacaaaa aatgtaaata catagcttgt taaatcttga ttgaacctta
    29161 agtaataagg gataaaaaat gacttgttca aaggcaaaga atatactatt aaatgatata
    29221 agtaacttag agataatatg tagtaagtca aaagaactat atagcatcag taagtaaaaa
    29281 gcgtaaaaac ttacataatg cactataaaa taaatgagtt agaaaataaa tataatttat
    29341 ataataaagt agtacaaaaa ggagtattta tgtttggata tgttaaaata aacaaaatgg
    29401 atttaacatt tagagaatat gattattaca aagcttacta ttgtggacta tgtaaatact
    29461 taaaaagaaa tcatggagaa atctctaggt tttctttgaa ttatgatata acatttttaa
    29521 ttgttttatt aacagcagta tataacccag agtctataag tacagaggaa gtgtgtatag
    29581 taaatccatt taaaaagaaa aaggtaatta caaatgatat tacagaatat gcagcaagta
    29641 tgaatattct tttaacgtat tataaattgg aagataattt aatggatgat aaacgcataa
    29701 aagataaatt ggcatattat atatataaaa acaaattaaa attagcatat gaaaagtatc
    29761 ctgaaaaagc agagtatata aaacaacaac taaatgaatt aaataagtta gaaaaagata
    29821 aaaatataaa tatagatgaa gtatctagta tatttggaaa tataatgggt gaagtatttg
    29881 tctataaaaa agatgaaaat gagagaaact taagaatgat aggttttaat ataggtaagt
    29941 atatatatct actagatgcc tatgaagatt tagatgaaga ttttaagaaa ggaagatata
    30001 atccatttat agagtatatt gataaaaatg atgagttaaa agaaaaagta aaaaaaataa
    30061 tagtaacatc attaggattt ttagctaggg gaattgataa tctaaatcta aataaaaatg
    30121 ttggaataat agaaaatata atttattctg gtgtttattt aagatatatt aatatattag
    30181 aaagtagagg tggaaagaat gtacagtaat acttataata atgaaaattt tatgagagca
    30241 agagcattca tagaaaatag tgaatttaaa aaagcatatg attttttaaa aactttgact
    30301 gacaaatgtg cagagtggta ttatttaact ggcttttctg caatgaacat aggatattat
    30361 gaagaaggtg aagacttctt aaaaagagca aaatttatgg agcctgaaaa tagtgaatat
    30421 agtgatgcac ttagaagtta tacacaatat agaaatgatt atagcaatag ggctgacaat
    30481 tataatagaa gaagacgtaa tgatttagat ggatgttgtt gctgttgctg tgatgattgc
    30541 tgttgttgtc taggtgacga ttgttgtgaa aattgtgcta agctttggtg tttagattca
    30601 tgttgtgaat gttttggtgg agatttaata acttgttgtt aggatgataa atatgagtat
    30661 aaaagttgct tatggaggag ttttattagc attaaatgtg atattgttga ctcttacaaa
    30721 tattattcct gtaaatacat tgtttattat ggggttagca tcacttttag tatcaattgt
    30781 aataatggaa tggggcttta agagtggaat cgctttttat ataggttcta tagttttagg
    30841 atttatagtg atggcaagta agtctcaatg gattgtatat tcacttacct ttggaatata
    30901 tggtattgta aaatatctta tagaaaaaga taggtctata tatattgagt attttatgaa
    30961 attagtattt gcaaatataa tgatacttat attgtatttt ttattaagaa caatagttta
    31021 tattccaata aacatattta ttataggttc atttgagata gcctttatag tatatgacta
    31081 tgtttacagt tcttttatag gttattacaa taataggtta agaaagatgc tatttaaaaa
    31141 ataatagttg atttttatat ttaattttaa tgaaattgta gtttggataa gtgtaaatga
    31201 tatatctgaa tatacattaa agcataaagc taaatttaat atattcttag tgcaacatat
    31261 aaaagctttg atttttagtc aaagctttta tatgttagat ataaatatta gatataatat
    31321 aagtttttaa aatagatagt ataaattaaa tatccactat atttacatct gtagatagag
    31381 aataaataat atcttttctt tctactatta tctcaacatt tttagaaatt tcctcatcaa
    31441 gtgatatttg agataaaagt tcctttgttg gatttattgc tattggattt ccaactcttt
    31501 ttagcatatt tatatcacca ttagtatctc cataggcata cgagtttgat aaatctaaat
    31561 catactttac aacaaaatca tttatagcat tattcttact tatagaatcc cacattggaa
    31621 taactgtgcc tgtaaatata ttattttcaa agacataatc acttcctaga aaatcggtta
    31681 cattatattt ttttgccatt ttttcaacaa gaaatccagg gctaccagat ataaatataa
    31741 ctatgtgtcc ttgatttaga tgccactcaa tccttgaacg tgtgtattta taaactctat
    31801 ctgcttttaa tttaattact tggtcacttg taaagttgat acaggtttta tctaatcctt
    31861 ttagtgaatc aacataaagg tcacatattt ctaatagata atcatcataa ttaccttgtc
    31921 ttttatccca atccataaaa gtgtctctag catgtttata ccaatttttt tggtcaatta
    31981 tatcgtattt aattaatttt ttaaaatgtt caaccataag agagtctcta taaagagtac
    32041 catctatatc aaaaaaagct gctatatttt tcataagacc acctcaatta atcatttcct
    32101 tatattatat tataaattgt atctaagttg ttaaaatata tgtataataa tttatatatt
    32161 aaaaaacaag tattttagag tttaaaggat gtgactatat gaattttaat tttgcaaagg
    32221 ctacaaattc tagacttatg ggcagtttag gtcttataat aaattggata gatgatgaaa
    32281 acaatcactt ttgtcaatat tttttattag atgcagaggg attaggatta gcagattatg
    32341 tgagtttaaa taacccaaca caagaagaag cttatatgga agaagaaaga ttgatgggag
    32401 gatttggttc agatagagtt gaattaacga aggatgaatc tttattttta gtatcttatt
    32461 ttggtaataa gaatctttat tatgataagc tattgccagg agataaatgt gagtatattg
    32521 atattataaa aaactataaa acagatttaa ttatagaaaa attatacaat aaaatatgta
    32581 aaagagttga tgaggaagtt gaatttataa actatatgac tatgagattt atagcatggg
    32641 atagagaaag tttaaaatat ttttctggaa gtgacgagat tgcaaatatg catattacta
    32701 atataaatgg aacattactt aaaaacgtgg taagtgataa aggtcaaggc agatatataa
    32761 gtgaagcttt atatgaagac aatgatggat attatatatg taaaattgct ttttgcataa
    32821 gtaagtgcta tgaaactggt tttagaatta attctctatt agtgacagat aaagaactta
    32881 tgtatgattt tgaggtattt gatgagattt ctaaaagtga atttgtaagt gtttacagtg
    32941 taaattcacc tgaagaattt gcaggagtat tttatagaga aaatccattt ctgttaaaaa
    33001 gtaatatgaa tgaaggtata ttttttacta gatttaattt taataatgac catgtaaaag
    33061 aaaatgtata tataataaac aatgatatga aagctatata ttacttaatg ggaaataagt
    33121 tttttattgg tacttataac gaaaatgatt gcaattatat caatgaaata agtcagtcta
    33181 attatagtga ctatattaaa tttgaagaga aatttttctt tgagcaaaat gcattatatg
    33241 actttgcaga atcaggttca ttagattttg atgatttttt ggaataataa atttagacat
    33301 tatttaagcg agattaactg aatttaatct cgcttaaatt tatttctata atattggggg
    33361 aatattatga ggaatacatt tattattgtg gtcaattatt aaaattttat acagtttatt
    33421 ataaaaaatt tatacttttc tttatgttgt ttgccaatat tagtctcaaa tacgagtacc
    33481 atactattct gacccaccaa cacaagaaag agttttttaa atgaaaaagt cagataaaat
    33541 taaattttat ctgacttttt ctatgtttat cttattagat tatgttaata tctgttgacc
    33601 gaataagcgc atactcagtc aactttctat acctataata atattggggg aatattatga
    33661 ggaatacatt tattattatg gtcaattatt aatgttttat acaacttgct caaaaaaata
    33721 tatattacat ttcttcctca tcaaattctt caatattagt agcctgtggt ataccttgta
    33781 tagacatatt actagaacca taaggagtag gatatatatt aggaggcata gtactaggca
    33841 taactacagg cataccttgc attgtattat gacatataac tcctggtatc atcataagta
    33901 cattaggagg catattttga ttacatgaga agttaggaat acccatagta ttattcatat
    33961 tataccccat attactgttc atgttattag gcacattgtt aggcataccc atgtt
//
LOCUS       DAEQJM010000041        33434 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.041, whole genome shotgun sequence.
ACCESSION   DAEQJM010000041 DAEQJM010000000
VERSION     DAEQJM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33434
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.041"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            668..1576
                     /gene="trxB"
                     /locus_tag="KRQ43_002341"
     CDS             668..1576
                     /gene="trxB"
                     /locus_tag="KRQ43_002341"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH2742692.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(1666..3489)
                     /gene="typA"
                     /locus_tag="KRQ43_002342"
     CDS             complement(1666..3489)
                     /gene="typA"
                     /locus_tag="KRQ43_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBH2742693.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            3701..3943
                     /locus_tag="KRQ43_002343"
     CDS             3701..3943
                     /locus_tag="KRQ43_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742694.1"
                     /translation="MLEVTKIIIKYFASESDTFIKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            4091..4282
                     /locus_tag="KRQ43_002344"
     CDS             4091..4282
                     /locus_tag="KRQ43_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HBH2742695.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            4573..7074
                     /locus_tag="KRQ43_002345"
     CDS             4573..7074
                     /locus_tag="KRQ43_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBH2742696.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNVLAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            7234..7902
                     /locus_tag="KRQ43_002346"
     CDS             7234..7902
                     /locus_tag="KRQ43_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742697.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            7886..9163
                     /locus_tag="KRQ43_002347"
     CDS             7886..9163
                     /locus_tag="KRQ43_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBH2742698.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEKSELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            9564..9785
                     /locus_tag="KRQ43_002348"
     CDS             9564..9785
                     /locus_tag="KRQ43_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742699.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(10074..10838)
                     /locus_tag="KRQ43_002349"
     CDS             complement(10074..10838)
                     /locus_tag="KRQ43_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH2742700.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKAPTPDIVDILSEFNVNVL"
     gene            11112..11786
                     /gene="fsa"
                     /locus_tag="KRQ43_002350"
     CDS             11112..11786
                     /gene="fsa"
                     /locus_tag="KRQ43_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH2742701.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILDEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(11908..13302)
                     /locus_tag="KRQ43_002351"
     CDS             complement(11908..13302)
                     /locus_tag="KRQ43_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBH2742702.1"
                     /translation="MGIILKPKQFYMTVIVTIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(13380..14726)
                     /locus_tag="KRQ43_002352"
     CDS             complement(13380..14726)
                     /locus_tag="KRQ43_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2742703.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGIQQMLFSIGNMTLQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGYWKTKAIVNHRINE"
     regulatory      14976..15078
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            15172..16548
                     /locus_tag="KRQ43_002353"
     CDS             15172..16548
                     /locus_tag="KRQ43_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH2742704.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCLGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFM
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(16662..17807)
                     /locus_tag="KRQ43_002354"
     CDS             complement(16662..17807)
                     /locus_tag="KRQ43_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH2742705.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     SRGNRSGNTISIITKKELDIIKDLQKEFSIVITPKTLQNGELIDIIK"
     gene            18059..18766
                     /locus_tag="KRQ43_002355"
     CDS             18059..18766
                     /locus_tag="KRQ43_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742706.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            18813..20408
                     /locus_tag="KRQ43_002356"
     CDS             18813..20408
                     /locus_tag="KRQ43_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742707.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADSREKQKIMGMILSVVIITG
                     LLIFYVTSISLSLVDILKQINQMEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFFNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFMFIGQISSRIKYKNLILIIGSIILMLLYTLLMTRLNSMSVEMLKN
                     SVSISETIRKIYPPIYYFVDALKTGSVVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKTYKFKSQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIIGTILILL
                     FGADKVGELLKLNIDFNFIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLGFEIQFIIVSICLIASFSMFVALMGLLS
                     NLLYPNLDWKNEMAVVKRSASMIITMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TFILDFMIWRIISTKGVRIFKNL"
     gene            20511..21593
                     /locus_tag="KRQ43_002357"
     CDS             20511..21593
                     /locus_tag="KRQ43_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH2742708.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            21742..21903
                     /locus_tag="KRQ43_002358"
     CDS             21742..21903
                     /locus_tag="KRQ43_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HBH2742709.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            22244..23512
                     /locus_tag="KRQ43_002359"
     CDS             22244..23512
                     /locus_tag="KRQ43_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH2742710.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            23707..24495
                     /locus_tag="KRQ43_002360"
     CDS             23707..24495
                     /locus_tag="KRQ43_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH2742711.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            24495..24944
                     /locus_tag="KRQ43_002361"
     CDS             24495..24944
                     /locus_tag="KRQ43_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH2742712.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            24948..27212
                     /locus_tag="KRQ43_002362"
     CDS             24948..27212
                     /locus_tag="KRQ43_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH2742713.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKNALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            27352..27663
                     /locus_tag="KRQ43_002363"
     CDS             27352..27663
                     /locus_tag="KRQ43_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742714.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            27949..28449
                     /locus_tag="KRQ43_002364"
     CDS             27949..28449
                     /locus_tag="KRQ43_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBH2742715.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIISGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            28506..29492
                     /locus_tag="KRQ43_002365"
     CDS             28506..29492
                     /locus_tag="KRQ43_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH2742716.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            29542..30264
                     /locus_tag="KRQ43_002366"
     CDS             29542..30264
                     /locus_tag="KRQ43_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBH2742717.1"
                     /translation="MENFNKNAKIIGIGVEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            30293..32227
                     /locus_tag="KRQ43_002367"
     CDS             30293..32227
                     /locus_tag="KRQ43_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2742718.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFIEESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALDGGYFFPVRWIEYGKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNKYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            32220..>33434
                     /locus_tag="KRQ43_002368"
     CDS             32220..>33434
                     /locus_tag="KRQ43_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBH2742719.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKIRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDECSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLGYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDD"
BASE COUNT        12999 a         3628 c         5462 g        11345 t
ORIGIN      
        1 aactttttta aaagtttaaa aacctagatt ttcatagtga tgaagctgtt tttaatgaaa
       61 gtaatcaaaa gataactatt aaatatctgt aatattacaa ttttatacta cactatatta
      121 caaaaaaagt ttacaaaact ttaatttgaa aaatgtaatt atatggtata tcatataaat
      181 ataagtaaat agtgctaata tttaaactat taatcataat tggttcaaca aaagtatata
      241 gttaataatg tttaatttga agaaattgtt agtgtgaaat tacatatata ttcaaattaa
      301 attcataaat atttcacata ataatagtat actgtaaaca aaaggaggta ttaaatatgg
      361 gaatagtact tataacagca gcattagttt tggttatgta tggactttca attctatcat
      421 atatatcaga aagcaatata ttagaagaca ctgtaaatga taaccaataa ggttttgaat
      481 tatataaata agtgagaact gtaaataaaa gttaattttt atttgcagtt tttttatata
      541 tatgtaaaat aaagttaatt aataaaaaat aatgttttgt ttgtagtata tatggataat
      601 aatagtaaag tataagaatg atgagaataa tatataagaa ataataatat aaagagaggt
      661 aaacattatg gtagatatca ttgtaattgg tgctggacca gcaggtttaa cttcagcaat
      721 ttatgctatg agagcagggt taagcgttac agtatttgaa aaaaatattt atggaggtca
      781 agttgcaagt acctctgagg tagaaaatta tccagcagtt caaaagattt ctggggtaga
      841 attttctaat aatatataca atcaagcagt tgctcaaggt gttgatattc agtttgatga
      901 ggttgaagag ataaatttag agggaaaagt aaaggttgta aaaacttctt caggtgaaca
      961 taaagcaaag gctgttattc ttgcaaatgg agttgaaaga cgtaaattag gttgtgcagg
     1021 ggaacaagaa tttacaggta gaggagtatc ttactgtgca acatgtgatg gagccttttt
     1081 taaagataaa gaagttgcta tagtaggtgg aggaaatact gcactagaag atgctttatt
     1141 tttagctaat aattgtacaa aagtgtattt aattcacaga agagatagtt ttagaggtga
     1201 agaagtgttg gagaaatctg tgaaagcaag agagaatatt gagatacttt acagtcatgg
     1261 tgtagaaaaa atagaaggag aaaagactgt atcgaaaata gaagtaaaaa acttaaagac
     1321 tgaagaaaaa agaactatag atgttagtgg tatttttatt gctataggtc ttaaacctaa
     1381 taataaaatg tttgaaaatg ttcttgattt ggatgaaggt ggatatataa tttcagatga
     1441 gtcttgtaca acatcagtag aaggtgtata tgtagcagga gatagtagaa ctaagttttt
     1501 acgtcaaata ataacagcag catcagatgg agctattgca gccgttcaag cagctaatta
     1561 tataaatgtt gaataatata aatttcaaat aaaaatagcc atataaactg aaataatttt
     1621 tcagtactat atggctattt tgttaattag aggtaaatgt acgttttatt taccttgtct
     1681 agatttgtta tatcttaatc tatcatgttc atttaagaat ctttttctaa gtcttataga
     1741 atcaggtgta atttcaacta attcatcatc ttctataaac tctagtgctt cttcaagagt
     1801 aaatattcta ggaggagata attttatagc atcatctgaa ccagaagcac gtacgttact
     1861 cattttcttg tttttacaag ggttgactac catatcatct tttctggaat tcataccaat
     1921 tatcatacct tcgtaaactt ctacaccagg gtctacaaac attacagctc tatcacttaa
     1981 ggcattaaga gaatacccca tagtaacacc aggtccttgt gctattaaaa caccatttcc
     2041 tcttgaaggt atttctcctt taaattcttc aaatttttca aatgaacgaa ctaaagtacc
     2101 ttctccacga gtagcgttta taaattcact tcgatatcct aaaagaccac gagtaggtgc
     2161 taagaactct atttttacat agtctccttc tattgacata gactccatca taccttttct
     2221 catgtttaat tcatttataa tagtaccaga gtaaacttca ggacagttta caacaactct
     2281 ttctattggt tccattagtt ttccatcttc tttatgcatt aaaacttcag gtttagaaac
     2341 accaacttca taaccttcac gtctcatatt ttcaagtagt atagataagt gaagctctcc
     2401 acgtccagaa actttgtatc catcagtagt atcaagaggt tcaactttaa gaccaacatt
     2461 tacttcaagt tccttttcaa gtctatcttt caaatgtcta gttgtaacga attttccact
     2521 ttttccaacg aatggagagt cgtttactaa gaagttcata gaaagagtag gctcttctat
     2581 ttttatcatt tccataggta gtggactatc taaatcgcat atagtttcac ctatagatat
     2641 atcaggaata ccagctataa caactatttc tccactagta gcttcatcaa cttcaacttg
     2701 ttttaaacct tcatacacag aaagttttga tacttttcct ttagatacaa cagaatcttc
     2761 tctacatata gcaacttgtg tattgttttt aagagtacct ttgtaaattc tacctatacc
     2821 aagtctacct acataatcat catatgcaag agctgatatt tggaattgta gaggttcatt
     2881 atcgtaatta ggataagctt caacgtgatt tacaatagtt ttaaatagag gagaaaggtc
     2941 ttcactatca tcatccattt caagtttagc aataccttgt ttagcaatac catatattat
     3001 aggaaattcg cattgctcat ctgttgcatt taagtctaca aataaatcga aaacttcatt
     3061 aactacttct tccgctctct ggtctttttt atcaatcttg tttataaata atattggttt
     3121 taaaccgaac tctaaagatt tttgtaaaac gaatctagtt tgaggcattg ggccttcact
     3181 agcatcaact aatagaataa ctgtgtcaac agttttcata acacgttcaa cttcagaaga
     3241 aaagtcactg tgtcctggag tatcaactat gtttattttg taatcttcat agtttattgc
     3301 acagtttttt gaatatatag ttatgcctct ttctttttca aggtcgttac tgtccataac
     3361 gcagtcttta actacttcgt tctttctaaa aacaccgctt tgagaaagga aagcatcaac
     3421 caatgttgat tttccagcgt caacgtgggc tataactgcg atatttataa ttttatgttt
     3481 ttgtgacatt tttgttgctc ccttcgatta aaataactta ttaattatag cacaatatat
     3541 tattaggtac aaggaggaat atattaaatt gtattaatat agtttaaatt ggataaaact
     3601 gttagttttg catctgaaaa ttattctgtt taaaaaaatt ttttagacaa ataataatct
     3661 taatagataa aaagattaat aaaagagtaa aggatgatat atgttggaag taaccaaaat
     3721 aataattaaa tattttgcaa gtgaaagtga tacttttata aaagaagaag tttgtaattt
     3781 tgaagaactt cttaagtggt ctcataaatt tattgaaggt aaaaagatag aagatgtttt
     3841 gtatataaag tctaaagaaa actataaagt aaatgtgatt aagtctttag aaattaagga
     3901 attggaaata gtgagaaaac aacagatacc accgtacatg tagtattaat aatatataaa
     3961 attaatatgt aatactcaca ataggatata aatggtatat atggtaataa tttatattaa
     4021 aaaaactttt ataaagttta tatttgggta taaaagtatt aattagacat taattaggag
     4081 gaacttaaat atgataagag tatgtccaaa ctgttcaaat gtggatgtaa ataagctaaa
     4141 aactttggtt ggagaagaaa atgtaaagac tggttgtata ggtcagtgta gagcatttaa
     4201 aaaagaagct gttggaataa tagacaatga gcttgaaata aaggaaacag aagcagagtt
     4261 ttttgaagca tgtaaagaat aaattttaaa taaaatataa attataataa atagagcatc
     4321 taaattgtat aagcattaaa caatttagat gctctatttt tatatataca tttaattatg
     4381 agtatacttt tctattaaat acaaataaat ataactaata catttattta ttaaaaaaat
     4441 attgatttaa tatacctata gggggtataa taaaaatata gatttctaaa taagtaattt
     4501 atcaatatta catatcaaaa taaaacgtta caaattagct gaaaatatat tgaaagaaag
     4561 gaagatttta ttatgagttc aaataaagtg gtagaaagtt ataaaattac aggtatgaca
     4621 tgtgcagctt gtgcaaaggc agtagaaaga gtaactaaga agatggatgg agtatatgac
     4681 caaagtgtaa atatagctac tgaaaaactt aaaatagaat atgataattc taaggttaat
     4741 tttgatgata taaagcaggt tgtagaaaaa gcaggatatg gaattataaa ggaagaaagt
     4801 aataaaaaaa ttgatatgaa aattgatgga atgacatgtg cagcttgtgc aaaagctgta
     4861 gagagagtgg taaaaaaatt ggatggagta gaaagtatta gtgtgaatat tgcaacagat
     4921 aaagctaata tagactatga cccatcaaaa gtaaaattat ctcaaataaa agcagctatt
     4981 gaaaaagctg gatataaacc aatagaagag gtaagaaata aggttgatgt ggatgaagat
     5041 aaattgagaa aagaaagaga aatgaagtct ttatttgtta aatttatagt tgcaatagta
     5101 tttgcagtac ctctgtttta tatagcaatg ggacctatga taataaagcc tatagggcca
     5161 tggcctttgc cagaaattat aaatcctatg acaaatactt ttaattatgc attaattcag
     5221 ttaattttag taataccagt aatgatagct ggttataaat tttatataaa tgggtttaaa
     5281 tcactttttt ctttaagccc taatatggat tctttagttg caataggaac attagccgca
     5341 tttttatata gtctatatac gacactacaa atagccaatg gacaaattca aggtatgcac
     5401 catcatcagt tgtattatga aagtgcagga ataataatag cacttatctt acttggtaaa
     5461 tatttagaat caaaatcaaa aggaaaaaca tcagaagcaa ttaaaaagct tatggggcta
     5521 caacctaaaa ctgcaatagt gttagttgat ggtaaagaag ttgaaactcc tatagaagaa
     5581 gtagagatag gagatatact attagtaaaa ccaggaacta aaatacccgt ggatggagtt
     5641 gtaatagaag gatatacatc agttgatgaa tcaatgctta caggtgaaag tataccagta
     5701 gaaaaaaatg ttggaagtaa ggtgacagga gctagtatta ataaaaatgg tgttattaag
     5761 tttaaggctg aaaaaattgg tggagatact gctcttgccc aaataataaa gttagttgaa
     5821 gatgcacaag gtacaaaagc acctattgct aaacttgccg atactgtatc tggatatttt
     5881 gtaccaatag taattgcaat agctgtagtt gcatcattat tgtggttttt aataggagga
     5941 aaagatatag tatttgtact tactatattt atatcagtac ttgtaattgc ttgtccttgt
     6001 gcattaggat tagcaacacc aactgctata atggttggga ctggaaaggg cgcagaaaat
     6061 ggaatcttga taaaaggtgg agaggcacta gaatctgcac ataaagtaaa tacagtgata
     6121 tttgataaga caggtactat aacagaagga aagccaaaag taacagatat agtattaaat
     6181 aataatgtaa aagaagaata tcttatcaag attgcttcaa gtgcagaaaa aggttcagag
     6241 catcctcttg gagaagcaat agttaagtat ggagaagaga agaatataaa atttgaaaaa
     6301 gttgataatt ttaaagccat accaggtgct ggtatacaag ttactattaa tgatgaaagt
     6361 atattacttg gaaatagaaa gcttatgaat gacaataata taaagcttgg ggatttagaa
     6421 gaaaaatcaa atgtattggc aagccaaggt aaaacaccta tgtatatagc tgtagatgga
     6481 aatttatcag gtataatagc agttgcagat gtagtcaaag aaagtagtaa aaaagcaata
     6541 gaaatacttc atgatatggg aataaaagtt gcaatggtaa ctggagataa tgcgaaaact
     6601 gcaaatgcta tagcaaatca agtaggtata gatatggttt tggcagaggt tttaccagaa
     6661 gataagtcaa aagaagttga aaaactacaa aatcaaggaa agtttgttgc aatggtaggg
     6721 gatggaataa atgatgcccc agctcttgca aaagcagata tagggatagc aataggaagt
     6781 ggaacggatg tagccattga atctgcggat atagtactta tgaagagtga tttaattgat
     6841 gttccaacag caattaaact tagtcatgaa actataaaaa atataaaaca aaacctattt
     6901 tgggcatttg gatataatac gattggtata cctgtagcag caggaatatt atatgtattt
     6961 ggaggacctt tattaaaccc aatgattgca gcagcagcaa tgagcttaag ttcagtttca
     7021 gtcgtatcaa atgcacttag acttaaaaac ttcaaggcat ataagagaga ttagattaat
     7081 aaattaaata aaatgtatcc aaaagagcta tctttaaatt aaaaggatta atttacaaat
     7141 taagatagct cttttttcat gtaaaattca caacaataag ataaaatata agtaatatac
     7201 gaaattttaa ataaaataga aaggattgat agaatgaatt cgtcaatact tgtaattgaa
     7261 gatgattcaa atatacaaga gttaatatca gaatttttaa gtgcagaagg ttatcaagtt
     7321 gatacagcaa atgatgggtt ggaaggtata caaaagttta agcaaggaag ttatgattta
     7381 gtaatattag atataatgat gccaaactta gatggttatg gagtttgtaa aatgataaga
     7441 aagtcatcaa gcgttccaat tatattttta actgctttaa atgatgaagg agaccaactt
     7501 aaagggtttg acttagaatg tgatgattat ataacaaaac cattttcatt taatcttctt
     7561 ataaaaagag tagaagcaat tttaaggcga agtaacaaga ctataaatga caaatttata
     7621 gtttttgaaa aattaaaatt agatttaaac acatatattg cagagataga tggagaacct
     7681 atagaactta cactaaaaga gtttaatata ttaaaagctt tgatagaaaa gtatccacaa
     7741 gttataacta gggaaggtct tttggatagt atatggggtt atgactatta tggagatact
     7801 aggattgttg atgcacatat aaaaaatata agaaaaaaaa tatcgttacc atatattaaa
     7861 actgtaaaag gaataggata tacacttgag aaggatattt gataagtggg aaaagttaag
     7921 tataaagtat aagttatttt caataacgac atcattatta atagcgttag ctttaataat
     7981 atatctaatt ttatattttt tattgccatc atattatcat gagtataaaa ttgagtctct
     8041 tcaagaaagt ttaaaatctt tagtagatag ttcaattcat ttcgatacat atactttaga
     8101 agaaagactt tattatatgg ctaaagacca aaatttggct attttattaa aagataacca
     8161 agggaaaatt gtatatggta agaatgaagt agttatttta agatatagta agtacatgat
     8221 taatagtctt gaggatgagt atagaacttc tatacctata tatactaaag atgcaaaaga
     8281 tggtccatat actttagaac tcgttatgcc attacaacca attgacgaag caaacgaagt
     8341 tataagaaaa ctaatgccat acatcatatc aatagcaata ttgatagcga ttattggagc
     8401 atatatatat tcaattgtaa taacaaagcc tcttataaat ataatagaga gtgagagaga
     8461 acaggaatat agaaggaagg attttgttgc tacaatatca catgaactaa aaactccaat
     8521 aaccataata agtggtcaaa ttgaaggtat gatttatagt gtaggtaagt ataaggatag
     8581 ggatacttat ctgaaaaaat catatgaatg tacacaagaa ttaaaagatt tagtaaatga
     8641 aatgatagag gtttcaaaat cagaaatact tgaaaaagat ttgaaattgg tatcaataaa
     8701 tataagtgaa ttattaaata gacttgtaaa gagacaagta tttttaatag aagaaaaaca
     8761 tatgaaaact attttaaaaa tagaagaaaa tttggaaatt aaagcagacc aagagagaat
     8821 aactaaggca atcaataata taataaataa tgccataaaa tattctcctg aaaaatcaga
     8881 gcttataatt agactctatg ataaaaataa acgaataagt aaaaagactt ctaatcaaag
     8941 agtggtttta gaaattgaaa atactggtgt aactatcgag aaacgttatt tagaagagat
     9001 atttaatcca ttttatagaa tagaaaaatc ccgttcaaga aaaactggag gaagtggact
     9061 tggactttat atagtcagtc aaatttttaa aagtcatggg tttgattata gcataaaaaa
     9121 caaagaaaac tctgtagtat tcacagtaga atttaaaaat taattactta ttataaagaa
     9181 tatataactt tcaataatag ttcattttaa aatcacaaaa aattcataat gaaactgtat
     9241 tatataaata taaagaagct taaaaccata aaatacacca actataatga tgagatttcc
     9301 ttacatcctc catataagtc atcattatag taacccaaca attaagttac tatgaattta
     9361 aaaaataaca ccgagcatat aatctatgct tagtgttatt tttattttga aataaaaaat
     9421 atttaattta ttgaaatgta tagatttaga cagtttaaac tatatttaag acttaaaaat
     9481 tataattgat attacaaata aatatatgta ctttgggaaa aataaatata ggaagtatta
     9541 tatttacaga ggaggtagtt ttgatggata gattaaaaag agatatgaaa aatatgaaag
     9601 aagatttaaa agaaggtgtt aaaaagacag cttatgttat gaaaaataca gctgaagatt
     9661 tgaaagatga tgcacaaggt gctatggtaa acttagaaat gaaaaaagat gagatgatgg
     9721 aaagatatga acaaaagaaa ttttctaaag aattagagaa gcaaatgaag aatgaaatga
     9781 aataagcttt tatttatgaa taacaaatta ttgtattcat ataaaaagta gccagtaata
     9841 ttaaatagtt tatttaagga aatagacttt ctaaaaataa ctgtattaga tttagaaagt
     9901 ctatttcaaa ttagttttat aaatagacat aaggataaag tagatgttat agaactagat
     9961 tttaaaaaat agatactaag gataaaataa atattataga aatatgtttt taagaatagt
    10021 tatcaaataa aaatttatat ttataagaaa tcctataaaa tatataatta aacttataaa
    10081 acatttacat taaattctga taaaatatct actatatcag gagtaggcgc tttttctgta
    10141 attatagaac taatatcttc taaatgagca aacttgaaat ttccatcaaa tttaaacttt
    10201 ttatcttcca taactataaa tactttttta cttgaattta ttatagcctt cttcgtgaga
    10261 ccatcttcaa tttcaaaagt tgtaagtgaa gagttgaata catctactcc acaacttccc
    10321 ataaaagtct tatcaaactt atatttcgat ataaactcta tagttggagt accgacaaaa
    10381 ccgtctaaac tgagatttaa taaacctcca gtggaaatta tatttaaatt atttggtttt
    10441 gaagtaacta catttagtat atccaacata tttgtaacaa gtgttacttt tttattactt
    10501 tcagctaaca actttgcaag caagatgtta attgtagaga tatctaaaaa tatagtttct
    10561 ctatcttcaa ttaaattaaa tgctttttct gctattattt tctttgttgg aatattaatt
    10621 tcttttctgt cttttgtatc ctgattctct agtgtttctc tagctagtac agctccccca
    10681 taaattcttc ttattgaaga aatcttttct atatttttta aatcttttct tatacaatct
    10741 tctgtaacat taaatttaga actgagctct ttgacagtaa ctctaccttc tttttttagg
    10801 atatttaata tagcttggat tctttcttct gcaaacattt tctacctctt ttcgcaatat
    10861 agtattatag taaatattat aagataaaat acaatatatc aactatttta acatgaaata
    10921 caaaattaat ttaatataaa aagtatgttt tttctaacta tatatttaga atttagtaaa
    10981 taaaaaaatt ataaaactaa gaaggaaaag caaaacaata ataaaaaata aaaaacaata
    11041 agcaaaatgt tgaaaataat accaaatcaa tatataataa gaataaagaa agattaaagg
    11101 gggatatttt aatgcaacta atcttagata caggtaatgt ggaggagatt aaggagttat
    11161 gtacttgttt accaatagat ggtgtaacta caaatccaag tattgtttca aaagaaaaaa
    11221 agaattttaa gcaacttata aatgaaattg gtgagattat aggtgaggat atgcctatac
    11281 atgctcaagt gttaagtaca aagtatgaag aaatattaga cgaagcatta tatataagta
    11341 gtttgagaaa aaatatatat gtaaaaatac ctgtaacaca agatggttta agagctataa
    11401 aagaccttca cagaaaaggt gtaaaaataa ctgctactgc aatattcact gctcatcaag
    11461 gttttttagc tgcaaaggct ggagcaaatt atattgcacc ttatgtaaat aggcttgata
    11521 atatatctgg tgatggagta gctatggttt cagaacttat aaaaataata gatacttata
    11581 aaatggatac aaaagtactt gcagccagtt ttaaaaatgc acaacaagtt atagaattaa
    11641 tgcaacatgg ggtgcatagt gttacagtac catatgatat ttgtaaatct atgatgaatc
    11701 atccattaac tgattggagt gtagataagt ttatagagga ttgggagaat acttttggaa
    11761 aaggaagtaa aacaaataat atttagtatt atggtaaaag agtagttttg tccaatttca
    11821 caagaactta tataaaaaga tgaaaatatg aattttcttt ttaataattt cgttattatc
    11881 ttaagttaat tcatattttc atctttttta gatttctagt cctataaatt tccaccaagg
    11941 gaatgttata catattatta taaagtaggt taaaggaatc aaagttaaac cgtatttgaa
    12001 aataaccttg ctattataca gattttcacc atgaccaacc attattgtag catgatgaaa
    12061 tggtaatatg tactgtatgc ttactataat gtagacaaat agacataaag taacactatt
    12121 ttcctttagt atatgtaaac ttccaagtaa tggtattact acagatgatg tagtgacagc
    12181 acttccaaga catatattca agattattgt gagagttatc aaaaacaata ttgaaataat
    12241 ttctgaagag tttggtataa actttatcaa ataatttccc attatatcta caactccaga
    12301 gtactttaac actcctccaa ttgaaaatgc tgctataaaa aaaataagga ccttccaatt
    12361 tatttctttt aaagtactaa atccaactat ttttcttagt aataaaagaa gtacacaaat
    12421 tgacattata attaatgtgt ttatgttatg tatgaactga gttaaaaaca taaaaaacat
    12481 tattcctagg cataaaaata cgtgtttttg ctctttgttt agcaaattaa attctttttt
    12541 taaattagaa tatgaaaaat gaagtttatt accctcaaga ttttcattag aaataaattt
    12601 tattgaatgc aattcttttt taaagacaaa gataaataaa aaataagtta taaaacaagt
    12661 aattatagtt ggaacagaca tataaaaagc ccattgaccc caatttatat tacaatttcc
    12721 aagttctagt acaacataat ttagaagggt gtctccattt acaaaaaaca ttgatgtaaa
    12781 ggtagatgct gtaaatatac taaataaaag tatagatttt gaatcttcag ttatctgttg
    12841 ttcttttaaa aactccttgt aaaaagcaga tacaagaata acccttggaa atggttgtgg
    12901 gataaaaaat attaaaagaa tacctaaaat atacgataaa agaatcatct ttttaggggt
    12961 atttacagta tttaaaatta acttctcaga aataattttt gcgacacctg tttttgtaac
    13021 tgcattagta attatgtatg caagaattat tatgtaaaaa ttttctgtaa ataaaaactg
    13081 taaaataacc tttattggtg caatgttaaa tataaacgct agaattacaa aaaacaatgc
    13141 aacaaaagtt ttttcaactg agtctacagc ccatatcaag atagttaaaa aagataagca
    13201 tatagaaaat tttatgttga aactgtaatt aagagagaag tagagaatta tggtaactat
    13261 aacagtcata taaaattgtt ttggcttaag aataataccc atttttatat tcacctccat
    13321 aatttattat atcataatgg aggtgaatac aatgaatgtg aatacatttt ataaaaagat
    13381 tattcattga ttctatgatt tacaatagct ttagttttcc aatacccttt cttatagtag
    13441 ataactgtaa caataagacc taaagtccaa ccaaaaggaa tacccatcca aattccgtct
    13501 gttccaaaaa atttagaaag catataagaa gctggaagtc ttccaagcca taaagatact
    13561 attgagctta taagtgcaaa catggaatca ccagcacctt tcattgcact tgaaagtaca
    13621 aaagaagttc caataaataa aaagaatggt cctattataa ataagtaaga agagccaatt
    13681 ttaatgacat ctttatcagt attgaataga gcaattagat tttccctaaa tagcaaaatt
    13741 aaagcaataa ctgtaactgc taaaactaag gtcattttta tagattctcg aatgcctttt
    13801 ttaacccttt cattttctcc agcacctatg ttttgagcaa caaaagtaga aacagcagaa
    13861 ccaagattca taataggtaa gcttataaaa ttttctatcc taagaccagc accaaaagct
    13921 gccatagcag atgtaccata actattaact aaaaattgaa gagtcatatt tccaattgaa
    13981 aacaacattt gttgaattcc acttggaagt cctaatctaa gtccatcttt aaatattttg
    14041 ttatcgtata caattccttt gattttaaat ttaagcactt catgtttttt atttaaataa
    14101 attatactta ttataaatga tactgcctga gccattatag tggcaagtgc aacgccctca
    14161 acacccattc ttagcactac aataaaagtt aagtctaaaa ctatatttag aattgtggct
    14221 attatcagaa aataaagtgg agttactgaa tctccaagtc ctctaagtat tgcacttact
    14281 gaattatatc cagcagaaaa taatattcca ctaaatatta tagtaagata caattttgat
    14341 tgagcaaaaa cggattctgg tgtattcata agcttaagca ttgggccacc aaatactatt
    14401 ccaagaatac ttattaatat agaaccaata aataaaagta tatatgtagt atcaatagta
    14461 gcttttacct tttttaaatc tcctgagcca taaaattgtg acactaaaat agaaaatcca
    14521 aggctaacac ccataagcgc tgccaccaat aaaaacatta tagggttagc tccagagact
    14581 gccgccattg cttcttttcc gataaatcta ccaactatta tactgtcagc tgtattgtat
    14641 agttgttgaa ataaactacc aataagcata ggcatggcaa aaaagaatat ggattttccc
    14701 tcatgacctg tagttaaatc tttcacctta ttcctccaaa taaaaaaatt attaatttat
    14761 tatagtataa tcttaacata aactttatat ccaaactata aataaattgt atcaaaatat
    14821 catatatttt tttaaaatgt aaagaatata attataattt gaatttaata aatcaatatt
    14881 taatataatc gaatattaat acaaaatcaa tacaatatat acgtatatat tgacaaaatt
    14941 aattatataa attaaaataa tattcgtaaa gaaaaattca tgttttgtac tgtataacat
    15001 ataattttga caatatgggt cataagtttc taccggaata ccgtaaatat tctgactatg
    15061 tatactatta tttagttaat taaatattta attaactgaa ttatgaagga tacggctcag
    15121 cttatcaact actgtgtcgt ttttttgtaa aatttaatag gaggtgttgt tatgcaaaca
    15181 acaaacagta gtactatgca gaaacttttt ccaattttga ctaataaaaa tgtcgacatg
    15241 aagaaggaaa taattgcagg agtaactact tttttaacta tggcttatat aatagctgta
    15301 aatccaaata ttttatctga gacaggcatg cctgcaggtg cacttgttac aggtacttgt
    15361 ttagcagcag catttggatg tattttaatg ggtgtagttg ctaaccttcc ttttgcttta
    15421 gcatcaggta tgggtcttaa tgcatttttt gcatatacag tagttttaca aatgggtgtt
    15481 ccttgggaag tagctcttac agcagtattt gtagaaggta ttatttttat agtattatca
    15541 gtaagtggag ttcgtgaggc tgttgtaaat gcgataccaa aaaatatgaa attagctgtt
    15601 acaggtggta taggaatatt tattgcactt ataggtctag ttaacagtgg aattgttatt
    15661 ggagaccaag ccactcttat caaaatgggt agatttacac cagcagtaat aataacttgt
    15721 ttaggattaa taattattgc tgtattagat aaaaaaagag ttaaaggttc tatacttttt
    15781 ggaatagtag tgagttcatt acttgcttgg gcatttgctt ttatgaatcc agagtatgca
    15841 caaaaattag gtatatattt acctggtgga ttatttaaat tcgaaagttt agcaccaata
    15901 gcaggtaaaa tagatttagg atatgtacta catccaacaa atataggtgg ttttttagta
    15961 gtagtttgta catttttatt tgttgatttt tttgatacag taggtacatt agttggtgtt
    16021 tgttctaaag caaacatgtt agatgaaaaa gggaatgttc ctaatgtagg tagagcctta
    16081 cttacagatg cggttgcaac tacagttggt gcaggacttg gagtatctac agttacaact
    16141 tatgttgaga gttcaacagg agttatcgca ggtggaagaa ctggatggac agcaataaca
    16201 gttggaattt tattcttagc tgcaatgttt ttctctcctg tatttatagc aattccatca
    16261 tgtgctacag caccagcttt aatatatgtt ggatatttaa tgcttggtac agttaaggat
    16321 atagagtttg ataatataac tgaaggtgtt ccagcttttg ttactattgc ttgtatggca
    16381 ttaacatata gtataggtga tggtttaact ttaggtatat taacttatgt tttcgtaaat
    16441 atattttata atatatttgg agctaaaaag gcagaagaca aaaaacatgt ttctgtagta
    16501 atgattgttc tggcaatatt atttataata aaactttggc tattataata ggtattattt
    16561 aaaattttaa tttaatataa aataaagggc tataatttat tatcaattgt gatgataaac
    16621 tacagctctt ttgtatttgt tgtattttcg tatttattgt attatttaat aatgtctatt
    16681 agttctccat tttgtaaagt tttaggtgta attactatac tgaactcttt ttgcaaatct
    16741 tttataatat ctaattcttt ttttgttatt attgagattg tgttaccact tcgatttcct
    16801 ctagaagttc gaccacatct atgcaggtat tcatttttac tttttggaaa atccaagtta
    16861 aaaacatgac ttacatccac aatatctagt ccacgagcag ataaatcagt tgtaattaaa
    16921 atctttgctt taccaagttt aaatttattt attgcattct ttctatcttc tttttccata
    16981 tttccaaaaa ttcctattgc tttgtaatta tgataattta gttttgatac taggacttct
    17041 atattttttt cattatttac aaatacaata gctttttttg gatttgtagc tgctaatgcc
    17101 tttctaagaa aagtaaattt atcccttatc tcacctaata aatatgagtg attgatgtta
    17161 ggatttattt gtgatttttc ctttgttttt attatttcaa actccttcat aagtttatca
    17221 caaattttta tagtgctatc agtaagactt gcagagcatc ctataatttg tctatctctt
    17281 aacgttgttc ttattatgtc ttctatacaa gttatatttt ttccattcaa tagattgtcc
    17341 acttcatcta agactatagt ttttatatta tgtgatttta gcttcttttg ttttatcaag
    17401 tctaaaactc ttccacaaga gccaattact atgtgtggtt ttactgcttt tatatttttt
    17461 atttgttttt gtatattgac ctccccaatt aaagctaaag aagtaacgga gagttctgca
    17521 tttttagcca ataattcaac ctggtttgta atctgcatta ctaattcatg cgtaggtgca
    17581 agtataagag cttgtgtttc tctttttgat gtatcaattt tttcaaatat aggtaaaagg
    17641 tacgctagtg tttttcctgt tccagtctgt gaattaatca ataaatcctt attttgaatt
    17701 atattcccta taacaagtga ctgaacttct gttggagaag ttatgtcttg ttttttaagt
    17761 ccatctatta gagtggaact tatttttaat tgttcaaatg tattcatatt ttgctcctta
    17821 tatttaataa ttatagtcaa ctatttttta ttatacattg tttattcaaa tcgaactata
    17881 tattctttta taattatgtg taatttgaaa gtaaatatca attatattta tacctttata
    17941 tttctgatac ctttgcattt tatagatttc taaaataaac aaataaaagt tgtaattgtt
    18001 tgatatttgt tatatattat atataacaaa tatcaaaact ataatatgga gggaaattat
    18061 gttaaaagta atcaatgtat ctaaatcata taaaaataaa aaagtagtaa gtagtgtctc
    18121 atttgatgta aatgatggag agctttttgg gtttatagga cataatggag caggtaaaac
    18181 tactactatt aaagcaattg ttggaataca cgattttgaa gagggagaag tactaataaa
    18241 ttctaaatct ataaaaaaac agcctgttga atgtaaaaag gaaatggcat atatacctga
    18301 taatccagat ttatacgagt cattaacggg tatacaatac cttaatttta tagctgacat
    18361 atttgaagtt gccaaagaca aaagagaaga gttaataaaa tattattcaa ataagtttga
    18421 actcaataaa gcattaggag atttaatatc ttcatattcg catggtatga aacaaaaatt
    18481 agctataatt tcggctttga tacacagccc aaaaatctta attcttgatg aaccttttgt
    18541 aggtcttgac ccaaaagctt cctttatatt gaaggaaatt atgagggagt tttgtgacaa
    18601 aggtggttgt atatttttct caacacacgt tttagaagtt gctgaaaaaa tttgtgataa
    18661 gattgccata ataaaagatg gaaatataat tgcttatgga actacagaag aagttaaggg
    18721 aagtaattca cttgaaagta tctttatgga attaatagag aaataaaatg ttttttatac
    18781 aatatagtgt ctaaagtgag gaatgataaa atatgagcaa tctaagtata ttaataaaaa
    18841 ctaatataat aaatgaattt aaattaaatg cgttaaaaaa agctgatagt agagaaaaac
    18901 aaaaaataat ggggatgata ctttcagttg ttattataac agggttattg attttttatg
    18961 taactagtat aagtctttct ttagttgata ttttaaagca aataaatcag atggaaatgc
    19021 tacttatatt tggatttgga ttatcaacat taacaactat tgttacatca ttatataaaa
    19081 cgtcatcata tctgtttcaa gcaaaagatt tagacctttt gactagttta cctataaaag
    19141 aatctactgt actagcaagt aagatattaa tgttggttgg agcaaactat ttattttctt
    19201 caatatgtat gattatacca gcagtggttt atttttttaa ttctgatgta agtataacgt
    19261 atttccctta tttgatactg ctatttttag ctttaccatt attaccaata gttgcttcat
    19321 caataatttt tatgtttata ggacagatat catcaagaat aaaatacaaa aatttaatat
    19381 taattatagg tagtattata ttgatgttgc tttatactct acttatgaca agacttaact
    19441 ctatgtcggt tgagatgtta aagaatagtg tatctatttc agagacgatt agaaaaatat
    19501 atccacctat atattatttt gttgacgctc ttaaaacagg aagtgtagtt tcctttttag
    19561 catttatagc aatttcaata ataccatttt ttatgtttgt aacattattt gcaaaaaaat
    19621 ttaaagatat aaatgctaag atgagtgaag gatataagtc aaaaacttat aaatttaaga
    19681 gccaaaaaac ttcaagacct tcaaaagctc tattaaaaaa agaatttaag agatatactt
    19741 cttcatttat atacttttta aattcatctg caggtttgtt attcctaata ataggtacaa
    19801 ttttaatatt attatttgga gcagataaag tgggtgagtt actgaaattg aatatagatt
    19861 ttaattttat aaaaatacaa ttattgggag tattcttctt tataatagta atgaattgta
    19921 caacatactg ttcaatttct cttgaaggaa aaaatttatg gatactgaaa tcttctccaa
    19981 tagatgaaag agaaatattc tggtcaaaaa tattgatgaa ttttttattg aatgcaccat
    20041 tatctatttt atgtttaata ttagtatcta taagattagg ttttgaaatt cagtttatta
    20101 ttgtatcaat ctgtttgatt gcaagttttt caatgtttgt ggcattgatg ggattattat
    20161 caaatttatt atatccaaac cttgattgga aaaatgagat ggctgtagta aaaagaagtg
    20221 caagtatgat aattacaatg ttagtatcat tagcttacgt aattatactt ggaggtatat
    20281 atgtattact tggaatttcg tttttaaata tatatattat tttggcaagt atacttactt
    20341 ttatattaga ttttatgata tggagaatta tttctactaa aggagtaaga atatttaaaa
    20401 atttataggt gtatttatgt caaataaaga cttatctttt ttagtcttgc aaataatagg
    20461 ttaagtagta tactatgtat agtgatatga aaaaatttag gagaaaataa atgagaaaat
    20521 tatccaaaag agaaaaagat tttattcaat atggattttt attatttttg atatgtatta
    20581 ctacttattt agtattaact actttagata taaaactaat acctaaaatt ataaggctag
    20641 taaataagac ttatatattt cttggcatat tgacaattat agtatatatg ataattgaat
    20701 ctattgtaac tcatttgata ataaatgcag ttcaaaaaac aaaagtaaaa tttattggta
    20761 ttaaaatggc tacaatggga ttttactata acttagttac tccatttgca tctgggagtc
    20821 aaccaatgca aatatatgca cttacaaaat atgatgtaag ccttagtaaa tcagtggcta
    20881 tagttactaa taaaactgta gtatttcaaa gtacagttac tgtattttgt ggaattttaa
    20941 ttttgctaaa taagtcatta ctgatggagc aagtacattc tgtgaaagtc ttgataactt
    21001 ttggaatgat tatgaatgta agtatgttgt taggtggact attaatagta tttagtccaa
    21061 aacaagtaaa aatgatagca gaagttttga ttaatttttt atctaaattt aaaacattta
    21121 aatttttaga ttcaaaacgt gatagaataa atcattatat tgatgattat aattattcta
    21181 taaaaatatt tattaaaaat gtaagaatct tagttttaag tatattactt actgtgttac
    21241 aattaatcgc atatttcagt atagtttatt gtgtgtataa agcctcaaat ttaagaggag
    21301 tttcatatgt acatataatg acattacagg tctttttata tatggctata tcaccaattc
    21361 caacaccagg aaatgttgga gctaatgagg ttacattttt tactatgttc tccaatataa
    21421 ttccaaaaga attattgggg tactctgtac tcttatatag tgggtttgta tactatttta
    21481 tattaatagt ttcaggttta tttacatttg gaacgcatta tacattaaat tcttggaaaa
    21541 aggaagataa agtaaattct aatttagata aggttattga aaaattaaat taataaaata
    21601 attagggaaa ttctatatat aaatatggtg ttgagtaagc tatattatat tgagatattt
    21661 cccttttttg attaaaatta tagaaatttg aaataataag taataaacag aaaaagtgat
    21721 attgttttga aaggagaaac tatgaaacaa gataaacaaa atgaaaaaca aagtgagatt
    21781 tctaagataa aacaaagcaa tgataataaa cttgaaatag ctcaagaatt acatgtaagt
    21841 aaaaatatag ggaatatgct tggatataga atagataaga aaaaaatgaa tagaccaagt
    21901 taatgaaaat gttgaaaatg gtacatttta aaaaatatat ataatgaaat gttttattgt
    21961 taaatttaaa cttattttaa tggaggaaaa agtcgaaaaa tatctaaaaa gatatggata
    22021 taaaaaatat taatatatat atactataaa cttgacaaaa tcaacctttt aataactagc
    22081 aaaaaatagc aaaattatat aagcgttatt taattatcaa aaatgaaagc taaattgcat
    22141 gtcctaaaaa aaatgattga taacatttat ttgtgtgcta taattatata gtaaaacaat
    22201 aagtatattg cataatgtat gcaaatcggg aggagagacg gacatggaag catctataca
    22261 cacaattgcc agcaataatt tattgataat ttttgctatt gtaagtataa ctggaataat
    22321 ttgtagtaag cttagtgaaa taataaaggt tccagatgta gtgttatatt tacttgtagg
    22381 tattttaata ggaccatcat ttttaaaatt tatagatatt cgtggatttc aaatagaaaa
    22441 tcaactaata cttacatttg gttctgcatt tattttatat ttaggtggaa aagaaataag
    22501 tttaaaagta ttgagaaatg tgaagatatc tgtattctta ttagctactt taggagttgt
    22561 gatatctgct tttataatgc aacaagtaat aggatttact tttgggataa gtgcaatgac
    22621 tgctttacta gcaggaacta taatagcatc aacagaccca gccactcttg tacctatatt
    22681 taatcaggta aagataaagg atagggtaaa acaaactgta ataagtgaat cagcttttaa
    22741 tgatgcaaca ggagctatac taacatcagc agtgttggct gtaattttgt caaataaatt
    22801 ttcattaggt gaaaatattt atgaactggg gacaatggtt attgtcggag ttttagttgg
    22861 tttaattaca ggaatactgc ttttgaaatt agttaatgat aaaccttatg gaatatttaa
    22921 agattttgca ccaataatat ctgttatttc agttgtagtt gcatatgaat tatctacaaa
    22981 attaggtgga agtggatata tgtcttgctt tattgtaggt ataataactg gtaacaagaa
    23041 aaactttaaa atttggttaa gtcaaaaatc ttatgatgca gatttttatg ttgctgaaac
    23101 tttaggtact atttgtcgta tggcaatatt tataatattg ggtagccaag ttaatttggc
    23161 tcagttaagt aaatatttta tgccatctgt aattacagta ttagtattaa tgtttatagc
    23221 aagaccactt tgcgttttag tttgtacact tgtagacagg gaagcaaaat ggagtaaaag
    23281 tgaaatatta tttatgatgt gggtaaggga aacaggcgta ataccagcag cactttgtgg
    23341 tattatttca gcaatgaaag ttcctggata cgaagtgatt tcatctgtag tatttatgac
    23401 tatattaatt acattagtaa tacaaggaag tactacaaaa ttagtagcta aaaaacttgg
    23461 attattagaa gaagaagtga taaatataag tgaaaaagta tcaacttttt aaagttttgc
    23521 tttaaaatag tacctgttaa tggctatttt aatattgtct aatgatgatt attgaaatag
    23581 tcattttttt atgtataagt aatttacaga atttacatat tagacatatt tattatcaaa
    23641 atttgttgaa gctatgatat aattagttgt atttaaaata agaatagcaa ataagggagg
    23701 aaatttatgt ttacggttat ggatattgta cagccagata cagtagaaga agcgtactca
    23761 attttaaata aaagaaaaac taaccaagta attggtggaa gtgctttttt aagaatgggg
    23821 aaaaaaagaa taggaacagg aatagaatta tctaaattaa atttagatta tataaaagag
    23881 tatgaagatt acgttgagat tggttctatg actactttta gaacattaga aacaagttcc
    23941 ataataaaaa ataattttgg aagaataata gaagattcag ttaaaaatat aataggagtt
    24001 cagtttagaa atgtagtaac agttggtgca acagtatttt ctaaatatgg tttttctgac
    24061 ttgatagtag cattactttc attagatacg gaagtagaat tatataatat tgggagaatt
    24121 agtcttgaag agtttctaaa tagagattat gagaaagatt tacttattaa gatatacata
    24181 aagaagacaa ataagaatgc ttcttataaa tcacttagaa atgcaaagag tgattatcca
    24241 attctaaatg tatctgtatc aaaacatatg gaacaattta agttatgtgt aggagcaaga
    24301 ccgcagaaag ctacgattgc aaaacaagct agtgaatttc tatctaacaa tgaaatcaat
    24361 gaaattaata tagataaagc agtagaaata gcatcagaag aactaacttt tggttctaac
    24421 atgagagcat ctagggagta tagaaaagct atgagtaaag tacttttaaa aagagctata
    24481 atggaggtta tttaatgtta gtaaagatta atataaatgg gaagaaaaaa agtgttgata
    24541 tagaaccaga agaatatctg gttgatactt taagaaaagt tggtaattta agtgtgaaaa
    24601 gaggttgtga cacaggctgt tgtggtttat gtacagtttt aattgacaag aaacctacat
    24661 tatcctgtgc aacactgaca ttgagagctt tagataaaga aataactaca attgaaggtt
    24721 tagaaaatga agttaaagaa tttagtgaag ttttggtaaa agaaggagct gagcaatgtg
    24781 gtttctgttc tcctggcttt atacttactg tacttgcaat gaaggatgag cttgaaaatc
    24841 ctacagatga tgaaataaag cattatctta caggaaatct atgtagatgt acagggtata
    24901 tgggacagtt aagagctatc aaaacttatc tggaggtaaa atagaacatg aatatagttg
    24961 gaaaaggaat caagaaaata gatggaatga gtatcacaac aggaaagcct gtatatacag
    25021 atgatttatc agcaaaaaat gctttggtgg taaagatact tagaagtcct cacgcttatg
    25081 caaaaataaa agatatagat acatcaaagg cagaaatggt tgatggtgtt gaatgtgttt
    25141 taacatataa agatgtacca aaatctcgat ttacacttgc tggtcaaaca tatccagagc
    25201 catctccata tgatagatta attcttgaag atgttgtaag atatgtaggt gacgaagtag
    25261 ctatagtggc agctatagat gaaaaaactg caattaaagc aatgaatctt atcaaagtaa
    25321 agtatgaagt acttacacct gttttggatt ttgaagaggc aataggaaat aaaactatgg
    25381 tacatgatga agatagacat tgtaactttg atataggtat gcaaagagaa aaaaatatag
    25441 tatcccatca tgattataca aaaggtgatg tagaaaaagt attaagtaat tgtgatgtag
    25501 tgattgaaga aacttattat actcaagctc aagcacatgc aatgatggag acgtataggg
    25561 catacaatta tttagaccat atgggaagat tggttgtagt aagttcaact caaataccat
    25621 ttcatgtaaa aagacattta tctcgtgcac tagaaatacc agctagcaaa attagggtta
    25681 taaaacctag aattggtggc ggatttggtg gtaaacaaac tgcgtgtgtt gagatttttt
    25741 ctgcaattgt tactttaaaa acagggaaac cagctaaaat aatttatgat agaaaagaaa
    25801 cttttaattg ttcaacaagt agacatgcaa tgagattaaa agttagacta ggtgctacaa
    25861 atgatggcat aataaaggca atagatataa aagcactttc tgatacagga gcatatggag
    25921 agcatgcttc tacaactatt ggtttggttg gagaaaaaac tttaccaatg tataataaag
    25981 ttgaagcaac aagatttatt gcagatgtgg tatatactaa taagatgcca gcaggagcac
    26041 ttagagggta tggagcatca caaggatgtt ttgctgttga atcaactata aatatgcttg
    26101 ctaataaatt aaaaatggac ccaacagatt taaggttaaa aaatgtggta acagaaggtg
    26161 aaactacatt tgcatatggt aaaactttaa atagtgtcga tttaataaaa tgtataaata
    26221 aaggcaaaga acttattgga tggaatgaaa aatatccttg taaacatctt gataatggaa
    26281 aaattagaag tgtgggtatg gcaattacta tgcaaggttc tggtatacaa ggtcttgata
    26341 agtcttcagc tgaaataaaa ttgaatgact gtggagatta tactcttatg ataggttcta
    26401 ctgatatggg tacaggaagt gatacgattt tagctcaaat ggctgctgag gttcttgata
    26461 caagcattga aaatataaca gttatatcag ctgatactga cttagttcca tatgacccag
    26521 gttcatatgc ttcaagtact acttatgtaa caggtatggc agtagttaag gcagctcaag
    26581 acttaagaga aaaaataatt tctgctggag caactaaact aggtgttgag aaggatgaag
    26641 tagaatttga tggtataaaa ttaactagta aaaaaggtag cactttatta ttcgatatag
    26701 cagttgattc tacaattggt ccagatacta atcaattaat aggtcttgct tctcatggta
    26761 gcccagtatc tcctccacct tttatagcag gttttgcaga aactgaaatt gacacagaaa
    26821 ctggaaaagt tgatttagta aattatgtag ctgtagtaga ttgtggaacg gttataaata
    26881 aaaatctagc taagatacaa gttgaaggtg gaattgttca agggattgga atggcattat
    26941 ttgaagaagt tagatacaca gaaaaaggaa gcatggacac aaatacattt atgcaataca
    27001 agattccagc tagatgtgat attggaaatg ttaaagtaga ttttgttgaa acttatgaac
    27061 caactggacc atttggtgct aaatctgttg gagaagttgt tataaataca cctttaccag
    27121 caatacaaga agctgtgttt aatggaattg gtgtaagaat aaatacactc cctattacac
    27181 ctgaaaaagt ttttatggaa atgaataaat aattatttat gaaaatttag actagtttta
    27241 catgttaaac aaccagttat gtcatacctg ttgaaagata tttaataagt agttattata
    27301 atattatgaa ttttacttat aaaatacaaa attaaataag gggatgatgt tttggctggt
    27361 aatctaaata atatgagagc agtaaataat tttagaggag ataagaacat tttagaatgt
    27421 ttagtcagct ttgagggtcg ttcaataagt cagagaaaag taagggtatt ttttaaagaa
    27481 aaacaaaatc aaatagaaat tgattttgca gaagaggaaa tttctaaatt ggttgaaaat
    27541 gttgttttaa atacatcata tcaagaaatg ttatatgatg aaatagagaa acaactggaa
    27601 attgattgta taggtacttg gatgatatta tctaaattaa aagatggtag tagagttcac
    27661 tgattttaaa ataaattatt agagcctaat tttaaggctc ttttttgctg tttttaatta
    27721 acaatagaaa atttatcttt agtttgtata taattttaat atcatatatt ctatatatat
    27781 aaaattgaat ttgtatgtat tatattgtat aatataaaat gaatttggaa aatagttcgc
    27841 taaaataatt tgtttttata aaattactgt ttaagtttat agattttgta taaaataaag
    27901 ttatgttatt aattttttta gaaataaaac ttttactagg agacagatat gagaaaaaat
    27961 agtattaata tagcactaac tgcagcaatt acagcaatct atgcagtttt aacattatca
    28021 ttgggattta taagttatgg accaatacaa tttagggtag cagagattat gatgcttttg
    28081 gcatttttag ataaaggata tatagtaggt cttacattag gttgtttttt agcaaatgta
    28141 ataggaccat atggtgtacc tgatataatt tctggaacat tagccacatt tataagtgca
    28201 agtatgattt atattactag aaagttaggt aaacaaaata aaagtacttt agttatagct
    28261 tctttatggc caactgttat aaattcgatt gtggttggtc taatgttaaa tgtattcttt
    28321 gggcttccat taattctatc tatgatacag gtaggttttg gagaatttgt agtagtaaca
    28381 attgtaggag taccattttt ctgcttttta atgaaaaaat ataaaaatgt cattaatatt
    28441 aaattttaaa tagtgtatag taatttaatt aattgagagt attattagtg aaaagaggtg
    28501 tttatttgtc gaaggtaaaa agattgactg atgtttggat atatattaat gataagcaaa
    28561 agtttacaat aaaagagttg tcagaggaat ttaatctttc agctaaaaca atacaacgat
    28621 atttaaaaga attaaataaa atgggacttc caattcaagc agaacaaggt agaaatggag
    28681 gttatagggt gctaaataat agctatatac ctcctgttat atttacagaa aaagaagtta
    28741 tgattatact atttgcactt aagtcacttc agatttataa ttataagtta atggaaatag
    28801 aaattaattc tataatgaga aaagtaagtt atgaacgtaa aagcagtata aaagtaggta
    28861 tagaaaatat taaaagatac attggctttg tagctaatga tactaatgat ggagatttta
    28921 agagtagtaa tgtaactgag ttttttagag cttcttcaga atctctaatt ttaaatatta
    28981 agtataagtg tggtaatcag attttggaaa aaaacgtatg ccctataggt atatatttaa
    29041 ataagggagc atggttttca ccagcatatg attgtaaaag tgataaaata atattagttc
    29101 atatagataa tataattgat ataaaaagaa caggagaaag taaaaaaata catataaact
    29161 tggaagaatg gttacatgaa gtatataaca atttatatgg aaatagttca actactaaaa
    29221 aatttggtga aattatttat ctaaatgtat tattaactaa agaaggtgtt tctaaaataa
    29281 aggacagttc ttggaattta gatatggagc taaatgaaga tggtagtgga ataattagta
    29341 cattcataaa ggttgaagat atagattgtt atgcttcgat tttatttttt attggaaata
    29401 atgctaaggt tatagagcca aaatttttga ataagctact ttatgataag gccaatgagt
    29461 taagatattt ttatgaagaa aatatggtat aatatttaga aatgttgaaa ttaaataatt
    29521 attaaggaga tatacgttat aatggaaaat tttaataaga atgctaaaat aattggtatt
    29581 ggagttgaag gtattaatat aataaatgaa gtagaagaaa aaataaaagc aaatatggat
    29641 atagaaaaaa taaacataaa tcaagagatt gaaaaagaat atgttagaag tcttttagat
    29701 ggtgtagata tattattttt gatatattca tctgaagata aacatattag agatattata
    29761 aaagctgttt catatatgtc aaacgaaaga agagttctat ctataggaat ggattgttca
    29821 gagaaagaaa ataaagaaga tttagagctt gggagagagt ttaaaatcaa taatgatagt
    29881 atatttaaat ttgttgattt aatgaatatc atggtagagt ctatttctga ttcttgcatg
    29941 ataaatatag atattactga tttaaaagaa gctattgtag gagataaagg aattaagtat
    30001 tcttttgaag agtttgaaga tacaaagtca tatagcgaga tagctgacat tttatttgac
    30061 aggatggaat atattggtga ggaatttata agtaagaaag gaattgtatt tgttgaagga
    30121 agtccagaat tttctataat ggaattgaat gatttaataa gtaatattca gagcaaggta
    30181 gaagaaagct atgaagtaat attttcttta tatataaagg aaaatttaaa tggaaatatt
    30241 agagtaggct tattgtataa ttagtatatt ttagatatta aggagagtgt atatgtctga
    30301 aaatataaga ggtacagagt attggttaat ggaagaattt ttttatcagg aaacagacac
    30361 accacagatt tttatagaag aaagcataat tgcacttgga tttgatataa aaataaattt
    30421 aaaaaaagta ttcagtatgg ggaaaaaatc agaaaagtat attaatgaga attgtaatga
    30481 taaagatttt ataaaaaagt ttatgtcgat taaaaaagga gattattttt tatataaagc
    30541 atatcaaaat atagaagaaa aagttaaatg taatgtgtct attggcatag ttgaagaaga
    30601 ttttgaaaat ggatatgaat taagtcatat tttagggcat acactaccag taaaatggat
    30661 gcataatttt gatacagttt caaattgtaa agtatataca agtgaatttt ataaattaaa
    30721 taataatgat attagttcat atttagaaat tattaagtca caagataaga aattattgag
    30781 aaaaagaata gaagaaagtg aaaataataa atggtattta aaaaactatt attataaaaa
    30841 tgtagataag tgtgtagatg atgaagaatt atttattcag cccattaatc tagaacaatt
    30901 agaaagccta aaaaatataa agacagatga ttatatttta ttgtataata gcgagaaagt
    30961 aatttgtgaa aatgaccata caatgaagag tctatttggc gtatgtcaag ttatggaagg
    31021 gttcgataaa gagaaagtaa gtgctttgga tggtggatat ttttttcctg ttagatggat
    31081 agagtatgga aaggagaata tagacggaaa tgcatgggtt atatttgaaa ataatagtat
    31141 agttgaaaag tatgtaaaaa gatttactaa taaaatgcca ttaaatacta tactttatgg
    31201 accaccagga actggtaaaa catacaatac aaaacagatg gtttacaatc tagtaagtga
    31261 aaccagtcta agaaacaaat actatacagg ttacttagat tataaaaaca atgtagaatt
    31321 ttgtacattt catcaatcat atggatatga ggaatttata gagggtctta agtctgatgg
    31381 tgaaggcaat tttaagccag aagatgggat attaaaggat atatctatag aagcatgtta
    31441 taatgcattg aaatttgaaa aaaagatgag ctttgagttg gaaaaagata gcttgacttt
    31501 agaaactata aaagacagga aaaagaaatt agtattagaa aatatagaat atagtgagag
    31561 ttttaatttt gaagaatcag aaaactatgt tttaataata gatgaaatta atagagggaa
    31621 tgtatctaaa atatttggtg agctaataac attattggaa gatgataaaa gacttactaa
    31681 atcaaatcaa actattgtca aactaccata ttcaaaggaa aaattttctc tacctccaaa
    31741 tttgtatata gttggaacta tgaacacatc agataaatca atagcacttt tagatatagc
    31801 tttaagaaga aggtttaatt ttgaagaaat tatgccagat tatgatttat tgtctattgt
    31861 agatggtata gatattagaa aaatgctata tacaatcaat aaaaggatag agtttttata
    31921 tgatagagac catgttattg gacaagctta tctacttgct gtagaaaata ttaatgatat
    31981 agtagtagta tttagaagta aaataatacc acttcttcaa gagtattttt attatgattc
    32041 agaaaaagta ggtttgattt taggaggaat tggaagaaat gaaaaagata aatacattgt
    32101 ttataaagaa aaacttatag cttctgagtt atttaaaaat aataatgcct caataatgga
    32161 gagtaaagtt aactattgta taaaacaaaa catatctagt gaggagctaa aaaatatata
    32221 tgagtaaaaa tatatatgtt aaggaaacct atgaatggat aagggtaggt aatggtgaaa
    32281 atgagcttac agaaattgaa tatgaaaaat tgcttaaata tctagagaac aataatgatg
    32341 tattaaaaag taatataata gatattaaat acaaaaaaat tagatttata aactatgtag
    32401 gcatcatatg ttttgaaaat gtaatacttg aaatacttcc taaattgtca ttaagtgata
    32461 atcttgtaaa agatagagag atactattac agatgctttc tatatgtaat aaaattccaa
    32521 ttacaatgaa tgaaaaaata agattgagtt tgaaaaatta taatctctta aatttttttg
    32581 ttatgtattt cattgagagt atgcaaacac agatgaaaaa aggtatttat tttgaatata
    32641 taaataaaat agagaactta aatgttatga ggggtaaaat attattaagt acatatgcaa
    32701 aagaaaaagg catttctcca atgaaaataa gatgtgaata tgatgagtgt agtgaaaata
    32761 atttcttgaa tcaagttctt aaaaaagcat gtatatctat tttatgtaga ataaatgaca
    32821 attcaattca aggcaagatt aaaaaaattt taagctattt tcaaaatgta gatttaattt
    32881 atatagatag aaaaaaactg ttgggttata aattttataa aaacaatgat agatttaaag
    32941 attgttattt actagctaga cttctacttt taaatctatc tatggataat agtcaaaata
    33001 atcaagaggc attttctata ttatttgaaa taaatacttt gtatgaagaa tatataggaa
    33061 ttttaatcaa aagtatatgg gacaattcat ttagagaaac atatatacaa gataagagta
    33121 aatttctttt gaaaaatgaa caaacaggta agaaaaactt taatttaaga ccggatatag
    33181 ttttatatga cttaaaaaat gaatatgaaa ttataattga cactaaatgg aaagctattg
    33241 aagtagattc aaatgttttt tataggtcaa gtgatatata ccagatgtat gcatatataa
    33301 cagcatatga aaatgcaaaa agatgtatat tattatatcc ttgtattcaa aaagataaga
    33361 attatagttc ctggaaatta tcagaatcat ttaagggtaa gtttatagaa gcaaaaactg
    33421 tgaggttaga tgat
//
LOCUS       DAEQJM010000042        33163 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.042, whole genome shotgun sequence.
ACCESSION   DAEQJM010000042 DAEQJM010000000
VERSION     DAEQJM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33163
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.042"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            121..1002
                     /locus_tag="KRQ43_002369"
     CDS             121..1002
                     /locus_tag="KRQ43_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HBH2742720.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKKGVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(1315..2094)
                     /gene="hisJ"
                     /locus_tag="KRQ43_002370"
     CDS             complement(1315..2094)
                     /gene="hisJ"
                     /locus_tag="KRQ43_002370"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HBH2742721.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEDLIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(2634..2984)
                     /locus_tag="KRQ43_002371"
     CDS             complement(2634..2984)
                     /locus_tag="KRQ43_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HBH2742722.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(3000..3416)
                     /locus_tag="KRQ43_002372"
     CDS             complement(3000..3416)
                     /locus_tag="KRQ43_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HBH2742723.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(3435..3626)
                     /locus_tag="KRQ43_002373"
     CDS             complement(3435..3626)
                     /locus_tag="KRQ43_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HBH2742724.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(3777..4592)
                     /locus_tag="KRQ43_002374"
     CDS             complement(3777..4592)
                     /locus_tag="KRQ43_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBH2742725.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(4639..5577)
                     /locus_tag="KRQ43_002375"
     CDS             complement(4639..5577)
                     /locus_tag="KRQ43_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH2742726.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDASNKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYIYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(5574..6446)
                     /locus_tag="KRQ43_002376"
     CDS             complement(5574..6446)
                     /locus_tag="KRQ43_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH2742727.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEK
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(6471..8399)
                     /locus_tag="KRQ43_002377"
     CDS             complement(6471..8399)
                     /locus_tag="KRQ43_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HBH2742728.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNSL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(8511..8888)
                     /gene="gcvH"
                     /locus_tag="KRQ43_002378"
     CDS             complement(8511..8888)
                     /gene="gcvH"
                     /locus_tag="KRQ43_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBH2742729.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(8975..11101)
                     /gene="cdhC"
                     /locus_tag="KRQ43_002379"
     CDS             complement(8975..11101)
                     /gene="cdhC"
                     /locus_tag="KRQ43_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HBH2742730.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(11158..11964)
                     /locus_tag="KRQ43_002380"
     CDS             complement(11158..11964)
                     /locus_tag="KRQ43_002380"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH2742731.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(12014..13381)
                     /locus_tag="KRQ43_002381"
     CDS             complement(12014..13381)
                     /locus_tag="KRQ43_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HBH2742732.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(13412..14356)
                     /locus_tag="KRQ43_002382"
     CDS             complement(13412..14356)
                     /locus_tag="KRQ43_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HBH2742733.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(14376..15146)
                     /locus_tag="KRQ43_002383"
     CDS             complement(14376..15146)
                     /locus_tag="KRQ43_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2742734.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(15202..16587)
                     /gene="lpdA"
                     /locus_tag="KRQ43_002384"
     CDS             complement(15202..16587)
                     /gene="lpdA"
                     /locus_tag="KRQ43_002384"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH2742735.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVIEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(16631..17512)
                     /locus_tag="KRQ43_002385"
     CDS             complement(16631..17512)
                     /locus_tag="KRQ43_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBH2742736.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMQKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(17548..18222)
                     /locus_tag="KRQ43_002386"
     CDS             complement(17548..18222)
                     /locus_tag="KRQ43_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HBH2742737.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(18259..19131)
                     /locus_tag="KRQ43_002387"
     CDS             complement(18259..19131)
                     /locus_tag="KRQ43_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HBH2742738.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLVKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(19223..19855)
                     /locus_tag="KRQ43_002388"
     CDS             complement(19223..19855)
                     /locus_tag="KRQ43_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HBH2742739.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKIEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(19960..21636)
                     /locus_tag="KRQ43_002389"
     CDS             complement(19960..21636)
                     /locus_tag="KRQ43_002389"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBH2742740.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(21885..22664)
                     /locus_tag="KRQ43_002390"
     CDS             complement(21885..22664)
                     /locus_tag="KRQ43_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2742741.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(22974..24893)
                     /gene="cooS"
                     /locus_tag="KRQ43_002391"
     CDS             complement(22974..24893)
                     /gene="cooS"
                     /locus_tag="KRQ43_002391"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH2742742.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(25500..26411)
                     /locus_tag="KRQ43_002392"
     CDS             complement(25500..26411)
                     /locus_tag="KRQ43_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH2742743.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(26527..26649)
                     /locus_tag="KRQ43_002393"
                     /pseudo
     CDS             complement(26527..26649)
                     /locus_tag="KRQ43_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
     gene            complement(26732..27874)
                     /locus_tag="KRQ43_002394"
     CDS             complement(26732..27874)
                     /locus_tag="KRQ43_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH2742744.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYKVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(27892..29646)
                     /locus_tag="KRQ43_002395"
     CDS             complement(27892..29646)
                     /locus_tag="KRQ43_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HBH2742745.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMKINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            29782..29988
                     /locus_tag="KRQ43_002396"
     CDS             29782..29988
                     /locus_tag="KRQ43_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742746.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(29993..30916)
                     /locus_tag="KRQ43_002397"
     CDS             complement(29993..30916)
                     /locus_tag="KRQ43_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742747.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(31170..32870)
                     /locus_tag="KRQ43_002398"
     CDS             complement(31170..32870)
                     /locus_tag="KRQ43_002398"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBH2742748.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
BASE COUNT        10054 a         6550 c         3673 g        12886 t
ORIGIN      
        1 tttaaataaa gttatatttt ttacaacagt tttgtaatta aaaacatatt gaaggtaaat
       61 ttaaaggtac tatatactat aaatatgtcg acacaataaa tttaaaaagg agaactaaat
      121 atgaaaaaaa gattaataat aatgatattg tctgttgtct tagtactatc aagtatactt
      181 acgatatttg catattcaaa tattaaatat aataataata aattgatata ttctaatatg
      241 atagataaaa aaactcaaaa tagtgtaaag gaaatcctaa aagaaaataa aattaatgaa
      301 aaagacatag atacatttat taaagcagtc aacaattata ataaattgca agttaaaata
      361 cttcaaaata atataaatat atctaaatct ggatattctt caatcaatgc aaaacaagtt
      421 ccatataacc tagaaaaatt gcaagataat tgggtgaaaa aattccctga ttatatggat
      481 gtaaattgta gaataactgc ttttagactt tttaaagatt ttataaattc aaataagaaa
      541 tttactggag actctattga tttgaatgtc gacttagaca ctataatgaa taataaagat
      601 gctaaattta gcaccaaaga tgtagaaaaa tttatcaact tcttttctgc aataccagct
      661 aaagatacag atgatacaat caaaattgca gaacaaataa aaaatgaatg gaaaaaaaga
      721 aaaatatctt ttaaaaataa taaaaatata tctattataa atggatttct tcgttatcca
      781 gaaactaaaa acgtatttat aggtcataca ggcatatgta ttaaaactaa aaatggcatt
      841 ctatttttag aaaaatatgg tgttacatca ccttatcaag ttactaaatt taaaaataaa
      901 aaaggtgtaa aaaattatat gtttaataga ttgaagatgt cagaaggtga aattgaattg
      961 cctgacccta taataatgga aaacgataaa cttatgaaat aataacttta aacgcaaaat
     1021 agtatttata attactaagt caatataata gagaaggtct atagatttgt gtaaatacaa
     1081 tcttatctac aatcttatat aagaatgttt atataaataa gatagattaa ttctaagtcc
     1141 tattattcta ttgaatttta ttattatttt acttagattc tattgttatt ttacttagaa
     1201 cttattgtta ttttatttaa gttctattac tattttcaat catataaatt tacaaaagac
     1261 tgtacataaa tttattttat acaaacttat ctacagtctt ttgtgtgaat atatctaaat
     1321 aatatcgtat ttatttattt cctctgcaca gtgagaatca gaacctaaaa ctaatggaat
     1381 atcgtatttt tttaccaact ctaataagta tccatctata taaggctctt tgcaatactc
     1441 ttttctattt ccagaaacat tataatcaag ttcataacct ttttctttaa ttaactttat
     1501 taagtcttca agaattgtat ttcctttata atcgtatgga aatacctgat taaactttct
     1561 aactaaattt aaatgaccta ttctttttgg tttatgtata cctaaatctg aatttacagc
     1621 ttttatcaat gtttcataat acttattata aacagcttca atacttccta atttgtcgat
     1681 taaattttga aactcctcta cactgtaatc tacacaataa taatcatcat caattttaat
     1741 tatatgtact gataaaagag agtcttctaa ttcctttcca tatttattta aattctcctt
     1801 tatcccttct tcgtatcctt ctataaaatc cacttccgac ccaacattta tcttgatttt
     1861 accctcatac ttttctttca acttcttgac atcattaaaa tactttggta aatcttcaat
     1921 actcatacaa ctatcatttt caggagcagg gtctctaaat ccatttgcat acggaaaatg
     1981 ttctgtaaat gtcatttctg ttattccaac atccattgct ctttgtacat atttttcaaa
     2041 atcatcctta cttccatgag gacaataagg tgaatgtata tgaccatctt tcataaataa
     2101 ttcactcctt ttttaaagaa aaaatctaat ataaatgcat aaatttttta acttcaaaat
     2161 aatattttta atcatgctaa tttttattat atctaatatt agagtaattt taaactgcct
     2221 tttaagtatc ttatctttag tactattttc aacttaacat taatattatt ttttaactta
     2281 acattaatac tatctttaaa tagtaatact caatatataa ttaatcaaat aactcaaatt
     2341 gtttgatgaa gcttttgcag tatttaaaga atatataatt atttaacatt aaataatcca
     2401 atcttgtaat aaaatttact cattaaagta tattacagaa aatatctcaa aataaacttt
     2461 ttagttcatg atatactctt ttttgcatga aattagatat atttttatca tttcaacaat
     2521 gaaagggagg cttacatcca tcttgagata accccttaga taaaattttt aataattaaa
     2581 catcataaaa tataaaaatc gcttatatca aacgtataag cgattaatta tatttacata
     2641 tgttttttag cctctaacaa cattttatta gcttcttcca tatactctat agccttttca
     2701 atactctttg ctgtttcttc ttttccaata gctctagcct tttcaaccca ctctctaaat
     2761 ccttcttcat gagtttcatt gtgatttatc caatgtacta aaagtatttt taaagttttt
     2821 tcatccttag actctgatga ttcctcatga ctatgttcat ggtcgtggtc gtgagcatgg
     2881 tcatgtggat gttcatgaca tatatctcca tgagtatgtt cgtggcagtg gtcatggtca
     2941 tgatgtccat gatgatatct tacaatctct ttatcaaaaa tcattagtta ttccccctgt
     3001 tattttatat taaactcttt ttttataagg tttacagaat cttttacaag tagtgctaat
     3061 ggtttacctt ctaatccaac taactccaca ttttctggca taataggtaa aagtatctta
     3121 agtgcctcac tgtctgcaat agcttcactt atattacaag taacttctcc catcatagaa
     3181 ttaggtatta ttacagaaat aggtgcaact attatatttg cttttttagc tgatactact
     3241 atagcatttt cccctgtagc tcctttatta gcatgagctt tcatcataga actagttgct
     3301 atagaattag tccctagtgc ataaatttct acatatgtag gtaactcttc tctcaaagaa
     3361 gaaactatct gggctccaat acctccaccc attccatcta tcactgctat tatcatatga
     3421 aattccccta ttaattaatt ttcttgtatt attatcttat ggtccatcaa tcttatttct
     3481 ttaattatcc catctattat cttttgctct cctaataaat ccgttaaata aatctttcca
     3541 tcacaagggt ctatattaac cacattttcc ataacctttt ctaactcatt attactttta
     3601 caaatgaaag ctgatgattc acacatataa atctcctcct aatatgattt ttattaaaaa
     3661 tcaaaaaaag attcccttag gtatttcaat actccaaaga aaccttcatg atttcagttt
     3721 ttgtatatta ttatacctta agtatatcac tttaatttat gtaaagtcaa ttaaagttaa
     3781 cgctttttat tatactcttc attcttgtat ttttcatata gttctttaac taattgcttc
     3841 tcataatcag tcaaatcgcc ctccacaaac tcaacattaa attgttcagc taatcccttt
     3901 actatgtttt tctgtagaat atctatgtct atttttctgc caatttcatt ttctattcca
     3961 cttgcttttt tagctgtaaa tttcatagct ctttctttca attctggtgt cttagttttt
     4021 attaatttaa acaatttttc tacatcaaaa tccagtatta ttgaaccatg ttgtaataaa
     4081 acaccatctt ttctgctttg agcacttcca attaccttct tattattaat agtaacttca
     4141 tatgatgcat gtgcattaaa acatgcagct gataaatttt ccctacttat tctctcgcct
     4201 ctatttaaat tatctgtttc tataccactt agattcaatc ctttaactag accttcactt
     4261 atatatctat aagataggtt gatgctctta tcgattaaag gattatcttc tcctataatt
     4321 atactataag ttagctcatt atcatgtaat acagctcttc cacctgtaat tcttctagta
     4381 tagtctatat tcatacatct acacttatct aaatctatct catcttccaa tttctgaaaa
     4441 tatcctatac tcaaacaagc tggttcccat gtataaaatc taagagttgg cttattatgt
     4501 cctttcttat atgcagtaaa tatagcttcg tcaattgcca tattcattgc tccttcatat
     4561 gatttattat gtataactct ccactgattc atgattatta cgcccccatt tttagtataa
     4621 atatatccta gaaatcctct atagatttat ttctcttatt gctaaatcta tctcactttg
     4681 atttaaaggt cttgaatagt tgtatatagt acttccgggt ctttcattat agtatggtct
     4741 attacaatcc ttacaacctc ttatttcaaa aggatagcct ttgtttatgt cttttaaaat
     4801 atcattgtca agctttatac tatttaagta tccattttta aacttaaaat actcttttgg
     4861 ataaccttta tttatcatat aagacattaa ctgtaccctt ctataacttt ctatgcttgg
     4921 ttgatttatc ttttccattt tagttcctct aactggagta aatgcaaata aactaatcgt
     4981 tacatcattt tcctttaaat aaatatataa attgtatata tcttcatgac tttcacccat
     5041 accaactatt atatgtgtac ttattttatt gggatatgat tttgacattt cagttataaa
     5101 ttttaacttt tcatcatagt tatttccttt tattttttca tatagttctt tatttgatgc
     5161 atctattgct attcctattt tatcaactcc tactgaaaaa aacttcttta tctgttcatc
     5221 attttctaat tttgcagata gtgaaattgg catgtctatc ttaccactta tatagtttat
     5281 aaagtctaaa acagagttat gtgcttcttc acttgccatt gattgaatac atattctctt
     5341 tatatttttt cctttataag cttttaaagc atctaatatt tcttcttttg aaaactctgg
     5401 ccaaattact cttgataatt tatcttttct agtactactt tctattgatt gagaacaaaa
     5461 actgcattta tttatacatt tttctccaat cattatatat gctgtggtag gaggtatatc
     5521 gctttttttg tttaatatcc caagctctat tgctgtccca actgatagtc taatcataaa
     5581 acgcaacact ccttacactc atttattgtc atattcattt ctatagcctt attctttgca
     5641 gaccttgatg gtaatactat tctattgact ccacacatta tagataattg gtctagctct
     5701 tttctataca ctcctcttgg tctcatacaa cctagattaa tttcagtatc tggtaaatta
     5761 attctagctt cacataaaat atctgctacc ccttctaact caggaggttc tacattttca
     5821 tactcagtcc cttttgttgg aataaggact ataaatgtaa gcttattagg aggatttttc
     5881 tgtaggtatt ctataatttc atattcaccc tttatttgtc ctccttttaa accaatacat
     5941 atatgtggtg ctacttctgt atgttcttgt attgtattat aaacttcaat ataatcttct
     6001 ttactctttt tcatcttata aacttctctt attgtctcat catcaaacac taaatcaaaa
     6061 gaaactatat ctaaatactt acacaactct acaatgctat ctttatccat aagacctaaa
     6121 tgagcattca atctatatcc tttctctttt aagtttttaa tggtattaat atgagtattt
     6181 atagggacat ctccctcata actacaaccg ccactcaata gaaagctagt tatattcctt
     6241 gattgtactt tttcctcata ttcttctatt ggcaccatat tgtttaagta gtgaccgttg
     6301 caatgggcac atttcaaact acattgattg cttgtagtac taagagctag tgtctggtta
     6361 ggataagcaa actctatttt atttccaaaa ttctttaatt taatatcaaa tgctattttc
     6421 attttttcag atagattctt attcatagtt tattccttct taagtacatt ttactcttct
     6481 agtaatttct ttgctgttgg gaactgctct atattcgtat gtggtaagaa acatgcagaa
     6541 ataaattcat ccatataact tggatataca ctaagttcaa cataagttat ttgattacct
     6601 atttcttcaa gtttattttt tgcatcttta cttatgagag ctaagtaaga accaacaagt
     6661 gaactattcc ctatataagt aaatttttct ctatcaatgt caggaagtaa ccctataatt
     6721 attgagtttt ctatgtctag gttgtttcct ataccacctg ctatataaac cctatctaat
     6781 atactaaaat ccatacctaa actatctaca agagtgtatg cacctgaata tatagctcct
     6841 ttagctctga tgaaattatc tatatcaact tcattgacta ctatatcatt ttctaaatca
     6901 aattcttctt taaatgctaa tacatactct cctatctcat gctcattaaa tctaactctc
     6961 ttattatcta aatccctgta tattttacct cttctatcta ttacaccttt agtaatcatt
     7021 tgacagatta aatcaattat accagaacca catataccaa ctggtgcaca ttcatcaata
     7081 atctttaatg ttggctctaa agtttcttta tcaataatta ctttctctat tgctcctgct
     7141 gatgccctca ttccacagct tatccctcca ccttcaaaag caggtcctgc tgaacatgca
     7201 cagctcatca tataatcttt atttccaaat acaatctctc cattagttcc taaatctata
     7261 aataaaacat tttcttcact tgaccatatc cctgctgata atacacctgc tgttatatct
     7321 cctcctacat aacttgcaac agatggagct aagtacacat atgcactgtc atttacaaaa
     7381 agaccaacat tttcacccat aagttttgga gattttaaaa atggtggtat gtaaggttct
     7441 tgtcttaaga agtctgtata cacacccaag aataaacttg tcatagttgt attcccggca
     7501 gccactaatg taactacatc ttccttatct attccatttc tttcatatat tgtttttaat
     7561 agtggattta tagtttcctc aactatagct ttatgaagtg tctctaatcc atttttctta
     7621 gttgaatata taattctatt tataacatct gctccatatt ttatctgtgc atttccagaa
     7681 gatgctttat ctactacctc ttttgaatat aggtctacta aacaaacaac tactgaagtt
     7741 gtaccaatat ctattgcaac tccgtataag gaattttctt tattaccttg ttctatattt
     7801 atgattgtaa gtttcttttg tttttgaaca tatgttattg taaccttaaa atcactcttt
     7861 ctaaatacag ttggcatttt tctaagtata tccaatctaa aatctatttc attatatcct
     7921 aggctatttc taacatatct ttccaatcta tctacatcac ttatattatc atctaaattt
     7981 ggttcttcca tttctatgta tttctttttt atatttgttt taaattgaag gttatgttct
     8041 tcaattattt ttttagctct ttcaaaaatt tccctatcct cttttttatt actaccttct
     8101 atcttcatac catgcataga agatgatact ttagaaggaa cttcaatttc tatatctgat
     8161 attacctttg tacaacaagc tagtatataa ccttgctccc actcatcatc tgttatatgt
     8221 cttgtttttt ctgtatcaac ttttccattc aataatttta ctttacactt cccacaagac
     8281 acgtttccat tacaaggagc atctatgaat atatctgcat ttcttgcaac ctctagtaat
     8341 atatcaccct cattacaata aacctcttta ttgtttggtg taaaactcac ttttatcatg
     8401 ttatccctcc caatttgttc tatatatgat aaaaggaaag tatagctaaa tttgcgtgca
     8461 ctcaaatttt actatacttt ccccaattat aataatatct taatctttaa ttattctaat
     8521 ccagcctcgt attctttatc acttaataac gtatcaagtt cagccacatc agctagtttt
     8581 acttttaata tccagttttc atatgggtct tcatttatac attctggctc atcttctaat
     8641 ttttcattaa cttccaatac ctcaccatta acaggagata ttaaatcaga agctacttta
     8701 gaagactcaa ctactccaaa atctactccc ttagttacag tatcttctac ttctggtgtt
     8761 tcaacaaaca atatttctcc taattgatct tgagcatagt ctgttatacc tatatataca
     8821 acatctccat caattacttt tacccactca tgatctttag agtattttaa ttctggtaat
     8881 aatttcattt cgatagaccc ccaatattat attattgatt aaattactta aatcatatta
     8941 atattatatc atattatttt aaattttcca tcaattacat tacactttcc atagctaatg
     9001 ctggatgacc tttttcttct aagaaagcta atactccttc agaatcgtca gctatagttt
     9061 catcacaaac catatcacag aagttttcta ttccagtcat ttctttaact gtagcattta
     9121 atttatcagc tacataatct tttaattctt ttggcatcca aactattctt tctggtccac
     9181 cttctgcata agcgaatttt ttagaagata tgaaatgtct tccgtgtccc ataaatcctg
     9241 gagtttgaac tcctccacct gtcatagaag caagttctcc gaaagtcata ccaactggag
     9301 taacacttgc aaattctctg ttaactacaa caaatccgtt tgcttctggc attataccac
     9361 agatacattc gaagcatcca caagaagtca ttgggtcttc tagtatagaa tataatgtaa
     9421 cagattcaac tgcaccttga gatatttggt ttacagtttc atttactgaa ttccatacac
     9481 ctgttctatc atctaagcac tcgccttttt ctattggttg acaaggacct gttgggtcta
     9541 attctttagt agccttagca tctaaccagc taactgctcc acaaagacca agtctttcag
     9601 gagtaacaac acaaacgtga gctggtgcaa atgattgaca taagttacaa gaatagaaag
     9661 tatcaacact ttcatcaact aatgaagcta atctttcatc tctagcattg tacttagcta
     9721 ttgcttctcc ttttaattca gacacttttt cagcatctgt aattatagtt atttcacact
     9781 tatcaactac tgattcaaat tcatctaaca tcttagcata taaaacttct cctatatgct
     9841 caagtctaaa tcctttatca aatgcatctt tagagattct tacccaagcc atatctcttt
     9901 gtccaacgtg cattacacct tctatatagt tcaagaagta gtggaaacgt ctttcaagaa
     9961 ctggctcgaa atcttcttgc atatttttac cagctatttt aactattaca gcaagcggta
    10021 atcttaatac accatctgca tcaacttcat ctatatttgg tcctattatt tctatcttat
    10081 ggtcttcaac ttctgttgct tctttcttaa caacaagctc ccaagcttca gttctgtttc
    10141 caccaaactc agcaaacata tcgctctttc taattctctc accttcaaat gctgctgcaa
    10201 atgaaactgg gataggtatt tcagtaactt ttatttttat tcctctagct tctaatgaag
    10261 tagctactat cttatcgtaa tctttttgag ttaataggtt cattggaact tcaagaactg
    10321 tttggtcagt tataactggg aatcctaaag ctattgctcc agcacctgca gatacaacta
    10381 attcacttaa tggtccaaat gcattaacaa atgcaggaac tctattagct gtgtactcta
    10441 ataatccgtt taaatcacca ggagttaatc caccgaatat taatgctgct cttactgcaa
    10501 cagatacaac gtgtataaca gaagttacat catatcctag aggtataact cttagctcaa
    10561 gacccatttt tactccagct tctatagctt ggtctataac tttaccaact aagaaagtta
    10621 gtaaaccttt agattggtaa tcttttataa cttttgctgc tgattctgca tctggacact
    10681 caccaagaac aactgcaaca ccaggtatat ctcctgtaac taatggtaca ccaagtgatc
    10741 tgattatagg gtcagttata tgacctgcac atggctcact atatggagca tccatagttg
    10801 aatattttaa tgcttcaatt acttctgcag ctaaagccgt agctaaacca gcattaaaag
    10861 catgttctag taaatgagtt ctatttatta aagattttac tacttctaaa gcaccttcta
    10921 agtcccctaa agtgttcatc ttttgtcctg ttgcagcata tatacaaggt aatgaatatg
    10981 ctgtatcagg gaaagcaact ttatgctctt ttccattctt ttctatagct tcagctaaca
    11041 tagcttgagc cgcacctaaa gcttgttctg accctgtaaa gattatatta tatagattca
    11101 ttctatttcc ccctttaata tttacaccta ttttttatta actataccct aaaaacccta
    11161 gaaagcaaat ccaccttcat ttaactctaa gaaagagtct gcatataaag atgccccgtt
    11221 gattatgtca caagatttta cagttttcat taattctggg tcacatggat tcattatagc
    11281 tgaactaaat ccattagcca ttgccattgc taagaatgca ctatctaaaa caggtctaac
    11341 atgcttagga catccattag atacgttaga taatcctcct gtagttaaaa gtcccatctc
    11401 agtcatcatt tttatagctt ctaaaacttc tacttgtttt tcttgcatac cttttataac
    11461 taagcataat gggtcaaata gtatatcagt tggctccatt cctaacatta agcctttttc
    11521 taatatttct tggcagtaag ccatacgctc atcattatct cttgggatac cttcttttgc
    11581 acataaacct ataaccattg cttcgtattc agctgctata tctattaaat caaatcttga
    11641 gccagcatca gcagagttta ttattggttt tgcattagtt ctatcataaa ctttaagtcc
    11701 agcttcgata gcttttttat tagctgtatc taatgctata ggaacattgt tgaactcaga
    11761 ttgaagtaat ttgattcccc atgtcattat ttcttcgcca tctctttcgg caggtcctat
    11821 attaaaatct atatagtgtg ctcctgcttc taattgctct tttgctcttt ttaagattgg
    11881 agctgggtct ctttctgcta atgcttttct tattgaaggt gatatacaat gtattctctc
    11941 acctataatc ataaattttt ccatttataa tgtccccctt taaatttaat attaatagtt
    12001 agttaatatt ttattagttt gtttggcatg ctttttcttg gtatcctttt aagaacttag
    12061 gtaattccat agattcctct ggtcctataa ctacattcca tcctggtaag ttatcttcta
    12121 tatcaccttt aagtactgca acttttcctg gaatgataag gtctttacaa ttagttactt
    12181 cttctacctt actttcttta atgaaagcag agattgagtt tccaccaaat ttaccagcag
    12241 cccaagatgt aagaactgaa tatccacctg catctggtat tactaaccat actggaactt
    12301 ttgatctttc tatatcacca gcaactatga agtaagttaa tgcaaagtca acagtaacta
    12361 atactggaga attttcatct gggttgttga ttggataaat ctttggttca actctcattg
    12421 gtctttgtgg gtcagtgtat atgttttgtc ttagtgcaaa taatggtaat gccttagcat
    12481 aactaatatc atctattact attatagaac cgtattttat agtgaatatt gatgataaag
    12541 caacttccat catagggttt gaattagata atctatttgc aaatactatt gaaggatatc
    12601 caaatgttct atcttgctct tttaaagctg ttcttctaac ttgtatagca ttagtgtaag
    12661 tatcttttat gttttctcct gttacatcta atactaattc tttatatcca gcggcttgaa
    12721 ttaattcaac tgtttcatat aattcttcta agctaccagc ttttacacct aatggtaaac
    12781 ttgctccttt aactacttct atcatatctt tgtagttctc tttagttgct ccatatacca
    12841 ttggtctagc atcttttaat acttcaacag cttctttaac tacttgtgca tcatcacaag
    12901 ctaaaatata agctacttct aatccactgc cttttatttt atctattaat tttaaatacg
    12961 catctttatc tccacaatac tctaaaacag ccatttcaac tttcatttgt tcaccaattc
    13021 ttacatagtc aacttttttc atgttagcta ttttagcatc tactgcttca tcactcatac
    13081 aagtacagaa tgaaactgca tatctatttc tacttactaa tgttttttca tgtctaaata
    13141 atactgtttc tccacctagt tcatactcag atgcaccagc accaactttt aaagctttca
    13201 ttaaaggtgc agtagcctct gataattttg ctatagcgtc atcagacata tgtgggcatt
    13261 tacctacttc tacagctcct gaagcaacct tcatagagaa agccatacaa gttgggaatc
    13321 cacaatcctt acagtttttc tttggtgtta atttaaatat atctaaagct tttaatgcca
    13381 ttattttttc cccctaacct taacaattta attaagctaa tgcgttaacc aattctttta
    13441 tagtttctat tgattttgga tgacgaagta taactgcgtt tgaaccacct actaaaacac
    13501 ttgctgcagt tgaaacttcc attgctatag ttctttcttc tggacaaccc caatctggct
    13561 catcttctat tggagctata gcttctttaa catgacctac ttcaaaagct actggtgtta
    13621 tgataggcat ttgtaatgtc ttatcatttt gaccaaatgc tgcaagtcta attctatcca
    13681 tagtagatgc aacgtactca tatccataac caactgctga acatccaaca ttcataacta
    13741 tattttcacc tttaacgcct agttgagtta acaatacgtt taattgttta gctaggttta
    13801 tatcaacaga agattcagct cctactttat gtgcataagc cataccagct gatgctccta
    13861 ctcctttgta gttatcttct actgctgaca taaataagca gttatgtcca tccaatgttt
    13921 gagctaattt ttcaaataat ttaccatctt tttcatgatt tcctgaacca gctacaacta
    13981 aaggtaattt tattgcttca attactgcct tagctacatc agcacattca tcaactgact
    14041 tatctaatcc atttgggtca gaaccatcaa attttaaaca aataaaatct gcttgtgtat
    14101 tagcttcaac atatttagcc cactctactg gacaattagc tacatctttg tataattcct
    14161 tatatgaatc agtccagctt tcaggataaa cgtctgatat ttgtatacct atttttggag
    14221 aattacctac ttctccatca aaactataaa aaggtaatac attttcccca cctaatttaa
    14281 ttgctttttc ccctattcct acttcaactt ctgatatttt tccagaatat ttttgagtag
    14341 acattttaaa tgccatattt ttttccccct taagcctatt ttaattctaa tttagcaaaa
    14401 atttctttca tagccacttt agattttgaa tcttcaggta aattaactaa aggaatacct
    14461 gtagaatcat attcatatat caattcatcc ataggtacaa caccgattag ctctaggtta
    14521 tgcttttcaa tttcttcttt aacaccatca ttcataaccc catttggaac tttatttaca
    14581 atcaaaagta ttcttccaac acttaacttt agttcctcag ctaaatctct tattctagca
    14641 acagcttgta tgctacgtct tgagcaatca ctaaccaata aaagtgtatc aacatgtcta
    14701 gtgacttttc tacttagatg ttccatacca gcttcgttgt ccatgactaa gtatttgtaa
    14761 tgaccagata ttttgtttac ttgttctcta agtatcccat ttacaaaaca gtaacatcct
    14821 tcaccttctg acctacccat tactaataag tcatatcctt cgccttcttc gattatagaa
    14881 tttaatctaa attgaagata ttgtgccttt gtcataccac cagggaatgc attgcctaac
    14941 ttttctcttt gatttacttc ttctcttatt tctcctattg ttgcttcaac ttcgatacct
    15001 aacacttcat ttatgttagc attggcatca gcatctacaa ctaatactgg tccctttttg
    15061 tccttaacca aataatcaat taaaagccct gtgagacttg ttttaccagt tccacctttt
    15121 cctgcaacag ctatattgta tcccatttta agacttcccc cttaaatcta gccacagagc
    15181 cttatgtact ctgtctgtct attataattt aggtacagaa tgaacacatt ctccatgtac
    15241 atcatgaagt gcttccatta gcccttcaga taaacttgga tgtggatgta ttgcatcccc
    15301 tacttgttct actgttaatc ctagatgaac agcaagtgac aactctgtca ataaatctgt
    15361 agcatgaggt cctactactg ctgcacctat tatcttatca gtttctttgt cagctataac
    15421 ttttacaaat ccttggaaat gtcctatagc ttgtgctttt ccaagacctc taaaatcaaa
    15481 ttgacctaca ttgtattcta caccttcagc ttcaagttgc ttttcagtct taccaacacc
    15541 agcaacttca ggttcagtat aaacacatct tggaattgct ctataatcta ctaccttagt
    15601 cttacctaaa gcattttcaa ctgctacgat accttcttta gaagcaacat gtgctaggaa
    15661 aggagtatct attatatcgc ctattgcgta tataccttct acattagttt caagatgttc
    15721 attaactact acttttcctc tttccatttc aattcctata tcttctactc cagaattgtc
    15781 aaggttaggt cttctaccaa cacatactaa tgcatattgt gcttctataa cctttccatt
    15841 agaaagagtt gcaaccgcct taccatcaac tacttcacaa gtttgtactc caatacctgt
    15901 aataacctta attttatctt tcttaaattg tctaagtagt tgtttagcta catctttgtc
    15961 ttcatttaat agtatttggt caaccatctc aactatagtt acttctgttc ctaaggctct
    16021 aaagaactgc cctatctcac atcctataac tccaccacct actattaaca tagactcagg
    16081 tatctcttca agtccaagaa cttcatcact agttattaca acttttccat catatgggaa
    16141 cattcttggt acaactggaa cagaaccatt tgctagtatt atcttatctg cttttatagt
    16201 ttctactgtt ccatcatctt tagttacttc tatagtgttt ttatcaatta attttccaaa
    16261 accattaact aagtttactc ctcttttttc aaataagaac tctataccac ttattaattg
    16321 gtttacaact ttattttttc tttccattat ggcagtgaag tttggcttaa ctgtaccatc
    16381 tatttctata ccaaaatcct ttgcttcttt tacagtattc aatactcctg aagaagcaag
    16441 aagtgcttta gttggtatac atcctgcatt taagcaagtt cctccaactc ttcttttttc
    16501 aataaccgtt acatctgcac caagcataga agcttttata gctgctacat atcctcctgg
    16561 tccaccacct actactacta tcttcatcct taattccccc aaacctaata taatctacaa
    16621 tcttgcaata ctataaacct gcggcatcca gtatagcagg tatattctct tctgccccaa
    16681 ttgccattat atgaacacca tcacataaat cttcttcttt taattgtttg ataagttccc
    16741 ctgccatttt tattccttca cttacccagt tttcttttcc agctgctctt aatctttcga
    16801 tttgttcatc tggaacgaat attcctggta catttgcagt cataaattta gccattcctg
    16861 gtgattttaa aggtactatt cctgctaata ccttgcaatc catatccctt gttaattctc
    16921 taaactttct cattgtattt atgtcataaa gtgcttgtgt ttggaaaaat ttagcccctg
    16981 cttttatctt cttttgcatt tttaataatt gaacttctat tggagaatat tctggagtta
    17041 ctgatgctcc cagataaaaa tctggagaac cttttaactt attaccagcc atgtccgtac
    17101 ctgccattaa agtctcagca gtttgaagta tccccacaga atctaaatca aacactccct
    17161 tagcctgtgg atggtctcct acgctagtat ggtctcctgt tagtgccaac aaattgttta
    17221 tcccaaatac acctgctgac aacatttctc cttgtatagc tattctattt ctatctctcc
    17281 ctgttatttg aataactggc tctaatccag catcttttaa taatttacat gtagcaagag
    17341 aagttgctct cataactgcc gattgaaagt ctgttacatt tgctgcatga actcttccaa
    17401 ctaacggctt tgcacattct attaaatgtg aaaggtcagt cccttttgga ggagccattt
    17461 cagtagtaac tgcaaatttt ccactttcta atgtttctct taataagctc atctctaatc
    17521 ccccttttaa ccttctaaaa aaaactttta tgaatttgct gctgcttctt tctttttctt
    17581 tgcacttaaa cttcttggat tattttgctt agaatagtct tttggtggtc ttatttctgc
    17641 taagttatct aattgtccta tagcttctag tctttcatat atctttatcc aagcacaatc
    17701 attctctgag tttacttcac acttaccatt tttagctcca ccacaagccc cattcataag
    17761 acctttagca cacatagtta ctggacatat cccacctgtc caaccaagtt cacagtctcc
    17821 acaagcctta caggcttctt catattctcc aactctttgt acttccccta taaacaaagt
    17881 attgttggct ggataaactg gcttatcttt taaattctta actattgtct gtgtaccatc
    17941 tccacatgct aaagataaaa ctgcatcagc ttccttagtc tcttctttta gagcctttaa
    18001 atccttttta gactttaaaa ggttacaagc agggtcaagc attacatatc ctaagatttt
    18061 tttgccttca ccttcaagag tttccttcat ttttaaaact tcttcttccc caccactttt
    18121 acaagttgct gcacattgat tacaaccaac taaaaccagc ttgtcaaaat cctttaagta
    18181 ccctagcact tcttctaatg gtttattttc agaaattatc atatctactt cccccctaaa
    18241 ccttccacat atatatctct atttattgtt ttgtaattta caagccttaa ctacatgttt
    18301 tgcaagtata gatgttgtaa ctgaaccaac ccccgctgga actggagtta tcattgatac
    18361 tttgtctaaa actgcatttg tatcaacatc tccacataaa tttccttctt catcaacatt
    18421 tataccaacg tctataacta ccgctccatc tttaacaaaa ctttcatcaa ccatcttagc
    18481 tctaccaata gctgctatta gcacgtctgc ctctgctgct acacctgata gatttttagt
    18541 ttttgaatga catattgtaa cagttgcatg ttcacttaat aaaagcattg atactggctt
    18601 tccaactacc attgatcttc caagaactgt taccttactt ccttttaaat caacattata
    18661 gtgttttaat atctcaacta ctgctgtagg tgtacatggt ggaaatccac ttttatcccc
    18721 ttccattacc ttagcagagt ttattggact aaaacaatct acgtcttttt ccggtgcaat
    18781 aacatatttt ataacttctt catttaagtg ttttggaaga ggtctaaaac ataatatacc
    18841 attaacattt ttgtcatcat taactctctt taatacatca atatattcct cttgtgttat
    18901 atcctcagct aactctaaca cttctgttgt tatacctatg ttttgacatc tctttagtgc
    18961 tcctctttca taagataaat catcacttct tgccccaact ctaactattg ttagtttagg
    19021 atttatacct tctttaacta gtaaatcgac ttcttttatt aattcttcac taattttatc
    19081 agctacaggt tttcctttta taatttgtcc tttagttgac attccttcca tacattcaca
    19141 actcccctac aagcaaactt aaattaattt attctatata ccacatatta ataacatagt
    19201 atctactttc gtcatttaaa aattattttc caagagcttt ttcaactttg gcataaactt
    19261 catcacaaat ttttacacca tcttcaacta acttatctac ttctattttt accttattaa
    19321 catattcttt atcttgtata gaatttatat ttataactac atttaattgt ccaccaagta
    19381 tagcagctct taaacactga actcctacac caacatcact tatagcaagt cttgaacctt
    19441 tatcaactaa atcttcatgt aacttaatag cttcatagca aactcttact atgtttaatg
    19501 gtacttcaca agcaactttt aatgcctttt ccattgtttc tgcttttatt cttttttctt
    19561 cttctgtttc tttaggaagc ccgtaagctt ttgataatgg taagaaacat tctgcatcat
    19621 catctatcat ttttaataaa tctttttcta actttcctgc cttacttaat atctctttta
    19681 cgctttcttc atactcagca tacttcttct tccctattgt aaggttacat accatactac
    19741 ctaaagccat acctattgca cctactagtg cagcagctcc cccaccacct ggtactgctt
    19801 ctttggaaga tagtacttct acaaaatcaa cacaagtttt atctgctatt ttcatgataa
    19861 tcctccttga aaggatgtag gaaaatatct caaattattc gagatatttt acgaactatt
    19921 ttaagatatc tcctactctt tatttataaa ttaatttcct tagaataatc cagctattac
    19981 tccattttca tcaacatcta ttttttctgc tgctggaact tttggtaatc ctggcatctt
    20041 cattatttct ccagtaagtg caactataaa tccagctcct gctgaaattg ttgcttgtct
    20101 tacagttatt ctaaatcctg ttggtctacc taatttagtt tggtcatcag ttaaagaata
    20161 ttgagtctta gccatacata ctggaacttt agtaaatcca agtttttcta agttagctat
    20221 ttccttatca gcttcaggag tataatctac accatctgct ccataaatct tagtagctat
    20281 agcatttatc ttgtctttta tagataaatc atcttcatag cagaatctaa agttattttc
    20341 ttcttcatcc aataatctta aaacttcttt agctactgca attccacctt ctccaccttt
    20401 tgcccatact tcagaaagag caacattaac acctaattcc ttacacttgt cttcaacaag
    20461 tttaagttca gcttcagtat caagtgggaa tctattgatt gcaacaactg ctggtaatcc
    20521 atatacttga gttatgtttt caacatgttt taataagttt ggaagtcctt tttcaagagc
    20581 ttctaggttt tcgttattta agtctgcttt agcaactcca ccattgtatt ttaatgctct
    20641 tacagtagca actattataa cagcatctgg ttttaagttt gccattctac attttatatc
    20701 taagaatttt tctgctccaa ggtcagcacc gaaaccagcc tcagttatta catagtctgc
    20761 aaagtgcata gccattcttg tagctataac agagttacat ccatgagcta tatttgcgaa
    20821 tggtccaccg tgtacaaatg atggtgttcc ttcaagagtt tgaactaggt ttggttttaa
    20881 agcatctttt aataatgcag ccatagcacc attagctttt aattgtctag ctgttacagg
    20941 ttcaccttca tagctgtatc caactattat gtttcctaat ctttctttta aatcagatat
    21001 atcacttgcc aaacagaacg ctgccattat ttcagaagca acagttatat cgaatccatc
    21061 ttgtctaact gctccatcac cttttttacc cataccatca acgatatttc taagttgtct
    21121 atcgttcatg tccacacatc ttctccaagt tattttctta gggtctattc taagtgcatt
    21181 tccttggtga atatggttat caagcatagc agctaaaaga ttgttagcag ctcctatagc
    21241 gtgaaaatct cctgtgaagt gtaagtttat atcttccata ggaacaactt gtgcatatcc
    21301 tccaccagct gctccacctt taacaccaaa tactggtcct agagatggtt ctcttaaagc
    21361 aactaataca tttttgtcta gtttagcaaa tgcatcagca acacctatag tagtagtagt
    21421 ttttccttca cctgctggag ttggatttat agctgtagtt agtattaact tagctttttt
    21481 accagtctct ctttttagta gattgtagtc aacttttgct ttgtatttac cataaagttc
    21541 tacatcatct tcacctagtc ctaatttttt tgcaacctct ctaatatctt gaggcttagc
    21601 ttcttgagct atttcaatgt cagatttaaa tcccataact gaatctcctc ccacaaccta
    21661 aatagattta aaatataatt tttgtaaaaa ttgtattaat atgtaaaaat tatattttat
    21721 aagataatta tacatgtaaa attacttaaa aactagctac taagctatta aaatattcaa
    21781 acttaatagc tagttattta tctaattact tacttattac ctatctattg cctatgtcta
    21841 acctttaacc aacttaaaat cccaaatcaa aatttctatc tattttattt atccttaagt
    21901 gacattaatt tatcttttat tgctttaatc tgttctttcg ttgtttcact agaatcatat
    21961 ggagattgat tagctctatc agaatcaata acatcttggt tatagtaaat aaatcctaaa
    22021 gattctccat cttctaagtt ttggattata aattcttcat cttccttatt tctaatttta
    22081 tttcctacta caaatacttt atttacacct atatcatgtc caagtttctt aacttttcta
    22141 taagtctgta gacttctctc tcctggttct acaactacta taaaagcatc tacaccttgg
    22201 gctgttcctc ttcctaagtg ttcaattccc gcttccatat ccataaccac tacatcttta
    22261 ttttgtagta ttaaatgtga gcagagtctc ttcaaaagaa catgctctgg acatacacat
    22321 ccagtaccac cagaatctac ggttcccaat gtaagtaatc ttactccatt gtattcttta
    22381 cagaaatttt cagggatatc gtctacttta ggattcatct taaacatttt tccaaatgaa
    22441 cctacagaag cagctgttct atctgaaact aattttttca tttctgatat aggtactatt
    22501 gattcatata cttcttttgg aaaacctagt gctaaagcta aattagcatc agggtcggca
    22561 tcaacagcaa caactctgta tccgtcttca gcaaacatcc tagagagcat tgaagaaaaa
    22621 gtcgttttac ctactccacc tttacctgtt attgctatct tcataatccc taccaccttt
    22681 tattactatt tgctttttag tagttaattt tacagttaaa tattttttat actctatatt
    22741 tttatacact aaaaataaac tacagctagt ccttacagga accaattaaa tttaccctac
    22801 tagcttttca aagcagcatg tatagtttta ttattcttta atattgttta tattttattt
    22861 attcagtata ttcattatat ttcgatgttc tttactttaa tatttgactt tattcaactt
    22921 tactcaacca gaaacttctt ataaaaacgt ttattctata acttcactat tttttaagct
    22981 tcagcctttt ctgccatttt ttcttcaact aatgcttcaa agtgaacacg ttttttctct
    23041 atatcttcta ttattgtagc tgctaactct tttggatttg tatttacagt aaatgtagct
    23101 ccaactttat cttttaactc actagttaat atatccactg ctcttgaaga accagctatt
    23161 ggaggcatta ttcctaaata agtgtctata ccagaagcta caacatagca tcctatagca
    23221 actgcttttt ctgacatcca ttctggagct atacctacaa ctggaaggtc acacatatcc
    23281 atatctaagt aattagctgc tgctccaact aaatctagta tacgacttat atcaacacaa
    23341 gaacccatat gtagtactgg tgggattcct actaatttac agacagttgc aagaccttta
    23401 cctgcatatt tttcagccgc atcagattcc attaaaccaa acttagctgc tgctgaagct
    23461 ccacaacctg tagtaactac tattatgtcg tttttgatta attctttcat tattgttacg
    23521 tgagcctcat ttgaaactcc tttagcattg ttacatccaa ctacaccagc tgctcctctt
    23581 aatactccag cttttagaca gtctgttaat ggcttaactg ttcctgctgg gtctatatga
    23641 gagtttacaa ctctgtctaa ttgatttact actgcttcta cactataccc aactgttgcg
    23701 cctgatttta attcaggtat aagtactttt gatttatctc tatttttaaa gtttaaaata
    23761 gcttctttaa ctattgcttt agcatcatca agtgcttgtt cttctctaaa ttcaatataa
    23821 gttgaacctg ttatcttagc ttttggagaa gttgttacaa atttagtatg gtaacaatct
    23881 gcaactctag ctaatgcagg gaatatacat tgaacgtcaa ctattacagc ttcaactgct
    23941 ccagttatta ttgcaagttc ttgttgatgg aagtctcctg ctatttttac accatgtctc
    24001 attgtaatct cattacctgt acaacacata cctgctaagt ttattccatc agcaccaact
    24061 tctttagcta aagctactaa gtctggctct tctgatgcta aaactatcat ttctgataat
    24121 gctggctcat gtccatgtaa tattatgtta actttatttt cttctaatac tgctaaatta
    24181 gcctctgttc ttcttggcac tggagttcca aataagatat cgcttagacg agtacctatc
    24241 atagaaccac cccaaccatc agccatagaa gttctaagac tcatgtgtat taaactatct
    24301 atatcaccag tacatcctat atgagtagag tgcattattg ttgcaatttc tctatctata
    24361 gctcttggct ctatagcgta ttctttccat attttttgtc ttggttctgg tgcatttttt
    24421 ataaatctta atgtcccaaa aggttttcca aattccatta atgcaatttc tgccacttca
    24481 tgtgctacat catagatatc tctaccttct gtctctacat cccattcttt agctaaagta
    24541 attaacttag cttcgtctct tattttatag tttccatttg gatcagctaa tgctaatgta
    24601 tgtgctatat ctctagcatg gtctgaatgg gcagctgtcc caccagcaac cattcttgca
    24661 aagtttctac ctactatagt atgctcatct gctccacata acccccttgg agtcttaggg
    24721 cttattctac atggtcccat tccacatatt ctacagcaaa caccttgaag accaaaacca
    24781 cattgtgcct taaagccttc ttttctatca tacattgttt ctacgccttc ttctctagct
    24841 ttagctatca tcttctggct gtttaaatca attgttaaca ttttttcatc catattccta
    24901 tccccttttt ttgattttta aaatccccca ggtgactgac ttcatgtcat aaaataataa
    24961 aataaatgct ttctaagttg attatatact aattttcagt gctttgcttt agatttaaat
    25021 atttttttaa caaaattaga taatacataa aaattttatt ttctacactt aatttaagtt
    25081 gattttatcg cttgtttttg gctatttgtt aatatctaaa cctacttttt tgatacttca
    25141 gtttaattaa attatgtttt gattttttta aatcaaattt gaaatttttc tagtcatttt
    25201 tatattattg cagattgttt gtgtatttat tatctttcac tactgtttgg acttattaca
    25261 gatttttact ccctaaactt aattagtaaa aacttcttag aatagcattt tttggactaa
    25321 tttttttgaa tttttttatt tttcctactt taatattaat tatagcttca aattgaacat
    25381 ttgtatatat tcatttgaag ctataattat tttttatata aaactttttt aatacagcat
    25441 taatttagac attttgacta ttttttctac tttaattcat ttatttcaag cgatttatcc
    25501 tatttcatat ttttagctac aatagcccca tatgcaatag aatataattt agattcatgt
    25561 gaatcagctc ttgacactaa aactatagga gcttttgcac ccataattat acctgctgat
    25621 ttagagtctg ccatatatgt aaaggctttc cctattccat tgccaacctc tattgttgga
    25681 accaatatga tatctacatc tccagatact tcacttttaa acccttttat ctcactagct
    25741 tcttttgaaa cagctaaatc aaaagccaga ggaccttcta caattacatt ttcaccaaat
    25801 tctccttctt tacaagcttt tgctaacata tctgcatcta cagttgcttg catcttagga
    25861 tttactttct ctttagctgc caaacatgca acttttacag tttccattcc taaagctttt
    25921 gcagctttta tagaattttt taatatcttt gccttttgtt cataatcagg agctatattc
    25981 atacctccat ctgtagttat aagtaattta tggtattttt ctaactcata taccataaca
    26041 tgacttaata aactatcagt tctaagacca tagtctttat ttaacacttc ttttaatatg
    26101 acagatgtat ctaataatcc tttcattaca aagtcggctt ctttacttga tactaattta
    26161 actgctattt ctgcacactc tttgatatca tccttatcca ctattttgat accacttaaa
    26221 tcaaatccta tttcttttga tatttctctt attttgcctt catttccaac caatatagga
    26281 gtaattatat ttctttctac agcatccttt attgccatta aaacttcttt atcatgagct
    26341 gctgctacag agagtacaat tttctctcct cccttaagtt gttctaaaat atcatctaat
    26401 ttttttatca aaagtaaccc ctcccttata tatatttaac taaataatac catatttgct
    26461 ataccttttc tcaatttatt ttttatgtta taaagaattt atatgactaa aagacagttt
    26521 aatattttat tctgggattt catcaatagc tcttaaaagc tttgcaggaa caccacctac
    26581 aatagtattt tttgttacaa ctgctccagc agcgataatt gcattatctc caatagtaac
    26641 tcctggaact cttcatacaa aaaagaggct tatctctatt ttgagatagc cccacttaac
    26701 cgataaaatt aaatacaacc taacaatatc cttacttatt tattccaagt tctcttagac
    26761 aagcaatagt aatttcatct tgtggattta attcataagc tctttctata tagtaagttg
    26821 catcatcaat atcaccatta tttaaataag ccattcctaa attgcaaagt atttctgggt
    26881 cttcctttat cttagccgct tgttcaaaat actctattgc tttatctaaa ttattcttat
    26941 aagcctcaca aagccccaat tccactatag tatccacctg attaggcttt attatcaata
    27001 tcttctcaag atacatctta gcctgctcta tttcgcccat acccttatat ccaagtgcta
    27061 tcataaacag caagttccac caatccatat gttcttcttc taatggaagt aacttctcta
    27121 atccttcctt aaacttacct tggaatacaa gtgtatatcc ttcttcatat tgaactttaa
    27181 agtccatctt gcctagattc tcttgtacct cagctactaa atcagcatct aaccctagcc
    27241 ttaatgcttc ttcccaagtc agcttagtct ttaaatattg accttgatta taataatggt
    27301 agcctaagtg ataataacct aatgcaaaat tctcatcaac atcaattacc ttttcaagct
    27361 tagccatggc ttcaagtaag aatgcattca ttgccttatc atccatatct ttttgatact
    27421 gtttagctat ctcttggcaa acaatcgcat agttatacat tgcatctaaa tcatctggat
    27481 acattgttat aaatgctttt atatatatta aagaatctgt atgttcacca atctcaaagt
    27541 attttctcga catatatccc atatacgatt tcaaatccaa atcaatatct tttgataaag
    27601 catttaaaaa cttctcatac tctgcattgt ttttaaactt actatctatt ccaattatat
    27661 atatcattgc atctgctata gacattgaat ttaacttatc ttgagcagtc ttttctttta
    27721 tcccttttac taatacctca ttttttatag gtacatctaa tccgcctttt ggcactttat
    27781 agctttttaa tttaaactct ccaccatgtt ttatagttat aaaagctaat tcttctgctt
    27841 tttttagcaa atatttttct atcttaaaat ccattttatc ctcctaaata cttaaatctc
    27901 tactttatga gttttagatt tctcaaatat ttttttatca tcatactcaa ataagactac
    27961 attttctact tctcttattt ctgtatttat atcatttttt aaatccacaa cattaaatct
    28021 aaatggctca aaatgaacat attttattat atgtttagct ggtttatcaa caaaactagg
    28081 taaatatgtt gataagttat cattatcttg taaaaataca tggcatctat tcttaaaatc
    28141 atccacatct agcttattaa aaaactgtgg tatatttgat gttttaccca gtgatatata
    28201 gtcatatttt aatatatcat tgaatacatc attatctatg ttgatttttt cattatagaa
    28261 atccatcaat attttatata actgattctt tccttgtgcc aaatcaaagt agccattttc
    28321 atcaaaatac ttggcaaaaa cctcaaagaa tttaaaagga ctttgtttat aaaatctgcc
    28381 tataatatat ctcatagata acacaaagtt tttagaattg tagtatctct ccagtatatc
    28441 ttctatatcc tttagcttca aagtttcttc atagcttata taattattgt ataaaaactc
    28501 atatggagca taatccttat atttaaaacc atgctcatct gcaacttttc tcatacctgt
    28561 ccctttaatc atctttaaaa agcctaattg cagatgctct atacctagat taaatacatc
    28621 attaaaagaa ttttcaaagc tcttataatc ttcataaggc agtcctgcaa ttaagtctaa
    28681 gtgctgatgt atatttctat aagatgctac agtttgtaca acatgagaca actttttaaa
    28741 atcatccctt ctacctactg catcaagtgt tttttcattc gttgactgaa cccctatttc
    28801 aaattgaaaa agaccttctt tacaatcagc caaaaactca agcatcttat catctatcaa
    28861 atacgctgta acttcaaaat gataagttgt atatccatta tcatttttca taaggaaatc
    28921 catgatttcc atagccactt ttctatttgc attgaatgtc ctatctataa actttatctg
    28981 tgatactctt gcatctatta aagcttttaa atcactcttt atcctgtcta aactaaaata
    29041 ccttagacct ggaatagtag atgataaaca gtactggcag ttaaaaggac aacctcttga
    29101 tgattcataa tacactattc tattttcata ttcttttgga ttcaagtttt cataaggact
    29161 aggaatctca tccaaatctt gaagtaattc cataggctta ttcactatta tctcattgcc
    29221 ttgtctatat acaagtccat ttacatcatt tattttcatc tttccttgca agtgaagtac
    29281 taagtctcta aaaattaatt ctccctctcc ataaagtata taatccacaa aatcatactt
    29341 tttcattgcc tcataactat cataactcac ttccggtccg cccaaagcta ttttagtatt
    29401 aggtctaatt ttttttagat tatcacaaag tttaactata tctcccacat tccagatata
    29461 tgttgagaat aatattatat catattcatt tttatatata tcctttaaaa tatagtccaa
    29521 atcgttgttt atcgtgtatt ctttcatatt aacttctatc aaatctctta caaattcttt
    29581 tagatatctt atagccaaat ttgtatgaat aaacttggaa tttaatgttg ttaataaaat
    29641 tttcaaatat ttctcacctc tttttaagat tatactgtct ttttgtaccc cttataggtt
    29701 aaaatagtat atgtaaagtc taaataatat ctatataatt aatttattaa tttcaagtaa
    29761 tgtgaggaaa ggaagttttt tatggaatta attgaaaaag tatctatcaa ctctttatca
    29821 aaaagagatt tactacttat tataaagtct cttgaataca ctaatgaaaa tactcaaatt
    29881 agtgatttca ttgaccttag gaataatata gtaaaggaat tatgtttttt aactgacact
    29941 aaggaaaaag attttttaga ttatctagaa aaaaatagca cactctaata acctaaacct
    30001 ttttaaactt taatatataa atacctgatt tagaatttat ttttatgctt aatatattat
    30061 cattaaaggt tttcgacata actgttattt gattaaatat agggtctatt atagtattac
    30121 cttcttcaag tcttataaga cttcttgggt ctatgctttt attatatgcc ttaactccaa
    30181 ttttatattt tctcaattta acaacatatt cggacataga aaaaataaaa tctatattat
    30241 cttcatttaa tttactatct tcacccaaaa tggataatat agattttttt atgctattaa
    30301 ttccttcatt ttctacagtt ctatcttcca tatatacatc atatagaaca tttaaaacat
    30361 ttaataaaat actttcttca tcataatctt cagatttcaa atcaatgtac ttatcaatta
    30421 attgtattgc tttaatcctt gccatctgaa actttacaac atctgatttg tctaattcta
    30481 tagaaaatcc tattatcttg tctttaatac tctgtagtaa ttcgacatac tctattttac
    30541 tattatttat aagattgtgc ataatggaat tatacactac agaacctaat aaataatcaa
    30601 ataaaagttc ttctttttta aaataaataa catacttttt tattagttta ataacctcat
    30661 cttcgctttt ttgaatatta gtatttgata aaattagtgg tagtaaaata tttaaaaaat
    30721 tgatatttcc tattttttct ccataaaatc tatagtaaat aagttcatct ctcagtctat
    30781 tttcgtctat atacacacat ctttgcgttt tatcatctat taaggatttt gtatttatta
    30841 tagttaaatc tttaagagcc ctacttgcac tactaaaaga agatgtgtag acttttttta
    30901 gtaattcgtc attcataaat atatcctttc tgaaaaattg aatgtaaata aattgttatt
    30961 aaaaaaaaag agacagcccg tttaagaagc tgtcatatat agggggatag tagtgtacaa
    31021 aaatcattgt aatctactat ctatatatta ttatacgata ctactttttt atatgtaaag
    31081 catcagtttt cgacatccct atattttaca gttatacaaa ttgcgtacta agttcaattt
    31141 tattcttttt atttcaacat tttatcatgc tacattcttt ccggagcgtg cattcccaac
    31201 aatttcagag aattttctaa agtttgtttt gttgctaaaa ctaatgcaag tcttgctttt
    31261 cttatttcca aattttctac taaaattgga ttgtcatgat aaaatttatt aaacgcttga
    31321 gctaaatcta acataaatct agtcactata tgtggctcat ttttctttag agcaagtaaa
    31381 atattcttat tgaatgattc tataactcta agaacttctg cactatcttc atcagctaat
    31441 agactataat ctatatcaga agtcacttct acttctgctt ttcttaaaac tgcacagcat
    31501 ctagcatgtg tatactgaac atatggtcca gtctcaccat caaaactaag cgttctttcc
    31561 caagagaagg tatagtcttt aattctactg ttagataact cttggaatac tactgcccca
    31621 acacctactt gcttagatat ttcatccaca tttttagcat ttggattttt agctagtata
    31681 atttccttag ttttatctat agcttgattt aaagcatctt ctaaaaatac tactcttcct
    31741 tttctagtcg acatagtacc ttcttcaagt gcaaccatac caaatccaac atgaattaaa
    31801 tcttttgccc aatcatatcc cataagctca attaccttaa accattgttg gaaatgtaag
    31861 ttttgttgag aaccaactac atatatacac ttgtcaaaat cataagtctc ttttctatat
    31921 attgcagcag ctaaatctct tgtcatatat aacgttgaac catcattctt agtaataagt
    31981 gctggtggca ttttatactc ttctaaatca acaattcttg ctcctttaga ctcttttaaa
    32041 agatttttct cttctaatag ttcgataact ctgttcattt tatcagaata aaaactctct
    32101 cctgctaaag aatcaaattc tatatctaaa agtttataca ctctgttaaa ctcttttaaa
    32161 ctctcatttc taaaccattg ccataattct tgtgcttctt cgtcaccatt ttctaattta
    32221 ttaaaccatg ctcttgcttc atcttccatt tctgggtgtt gttcagcttc atcatggaat
    32281 cttacgtata attttagtaa ttctggaatt ggattagact ctactacttc tttttctccc
    32341 cactttttaa aggccactat taacttacca aactgagttc catagtcacc taaatgattt
    32401 attcttatag tcttgtatcc ttgcgaatca tatatcttat ataaagcatt acctataact
    32461 gtagttctta tgtgccctat atggaaaggt tttgctatat ttggagaaga atattcaact
    32521 attacagttt tatcttttcc aaaatcacta tgtccgtaat tttctttttc atctaaaact
    32581 tttttaatta cagtttctgc taattgagat ttatttacaa agaaatttac atatccgcct
    32641 aattgtatta cttttgttat ctctccactt ggttctatac tttccgccaa ttcacttgct
    32701 atcatgtttg gagcttttct aaacactttg gctaatttaa agcatggaaa agcatagtcc
    32761 cccatatcct tatttggtgg aacttctata agtgcctcta tctcttcttt cgataaatct
    32821 tctatttttt ctttaaggca atttgatatt gccaccttaa aatcttgcat tctgttgctc
    32881 ctctctacat tgttcctggt ttatattgtg cttatctctt tatgttaaat caaatttcgt
    32941 gttttttcaa gtatttcatt acagtgtaaa acactttaat aattatgttt tctgtatata
    33001 ttaaaaatac tataattgca gtttttaatc acactattat tgatttttta taagactttt
    33061 ttctatttta ttgtttcttg tactatccag ttgactttat atactttttt taatctttta
    33121 tcaattttca tacatcaata ttaattttat atacatttat ttt
//
LOCUS       DAEQJM010000043        32589 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.043, whole genome shotgun sequence.
ACCESSION   DAEQJM010000043 DAEQJM010000000
VERSION     DAEQJM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32589
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.043"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            585..758
                     /locus_tag="KRQ43_002399"
     CDS             585..758
                     /locus_tag="KRQ43_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBH2742749.1"
                     /translation="MHLVQLLCQQINGSDIDPDSKFGPATYNQVKILQGRLGVTKDGV
                     VGKATWQAVGERY"
     gene            complement(843..1865)
                     /locus_tag="KRQ43_002400"
     CDS             complement(843..1865)
                     /locus_tag="KRQ43_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH2742750.1"
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTLLNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNSGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTKLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(2196..2378)
                     /locus_tag="KRQ43_002401"
     CDS             complement(2196..2378)
                     /locus_tag="KRQ43_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742751.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMVKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            2691..3110
                     /locus_tag="KRQ43_002402"
     CDS             2691..3110
                     /locus_tag="KRQ43_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HBH2742752.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            3241..5082
                     /locus_tag="KRQ43_002403"
     CDS             3241..5082
                     /locus_tag="KRQ43_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH2742753.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFVENKIGVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSIEYLNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNQSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYTIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKN
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIETEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMFMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIREIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            5109..6995
                     /locus_tag="KRQ43_002404"
     CDS             5109..6995
                     /locus_tag="KRQ43_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH2742754.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKEDSDIISKIYIYLT
                     LSAISIRKYDKANNFYFSAKKVIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSKNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELRKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNGTRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            7003..9003
                     /locus_tag="KRQ43_002405"
     CDS             7003..9003
                     /locus_tag="KRQ43_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2742755.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTREFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            9265..10524
                     /locus_tag="KRQ43_002406"
     CDS             9265..10524
                     /locus_tag="KRQ43_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH2742756.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVEEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            10585..12372
                     /gene="iorA"
                     /locus_tag="KRQ43_002407"
     CDS             10585..12372
                     /gene="iorA"
                     /locus_tag="KRQ43_002407"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HBH2742757.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEMNDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            12374..12949
                     /locus_tag="KRQ43_002408"
     CDS             12374..12949
                     /locus_tag="KRQ43_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HBH2742758.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            13002..14072
                     /gene="buk"
                     /locus_tag="KRQ43_002409"
     CDS             13002..14072
                     /gene="buk"
                     /locus_tag="KRQ43_002409"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH2742759.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            14290..14991
                     /locus_tag="KRQ43_002410"
     CDS             14290..14991
                     /locus_tag="KRQ43_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742760.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKRSN
                     EHKCKSSIVIKNEQN"
     gene            15050..15556
                     /locus_tag="KRQ43_002411"
     CDS             15050..15556
                     /locus_tag="KRQ43_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBH2742761.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEMYELLYE
                     IDNNKLNI"
     gene            15731..16753
                     /locus_tag="KRQ43_002412"
     CDS             15731..16753
                     /locus_tag="KRQ43_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH2742762.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(16900..17208)
                     /locus_tag="KRQ43_002413"
     CDS             complement(16900..17208)
                     /locus_tag="KRQ43_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH2742763.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(17268..17696)
                     /locus_tag="KRQ43_002414"
     CDS             complement(17268..17696)
                     /locus_tag="KRQ43_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742764.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(17919..19376)
                     /locus_tag="KRQ43_002415"
     CDS             complement(17919..19376)
                     /locus_tag="KRQ43_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH2742765.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            19794..20708
                     /gene="nadA"
                     /locus_tag="KRQ43_002416"
     CDS             19794..20708
                     /gene="nadA"
                     /locus_tag="KRQ43_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBH2742766.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKLLSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            20721..22022
                     /locus_tag="KRQ43_002417"
     CDS             20721..22022
                     /locus_tag="KRQ43_002417"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBH2742767.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            22003..22839
                     /gene="nadC"
                     /locus_tag="KRQ43_002418"
     CDS             22003..22839
                     /gene="nadC"
                     /locus_tag="KRQ43_002418"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBH2742768.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            23095..23427
                     /locus_tag="KRQ43_002419"
     CDS             23095..23427
                     /locus_tag="KRQ43_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBH2742769.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            23589..23774
                     /locus_tag="KRQ43_002420"
     CDS             23589..23774
                     /locus_tag="KRQ43_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742770.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            23801..24886
                     /locus_tag="KRQ43_002421"
     CDS             23801..24886
                     /locus_tag="KRQ43_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH2742771.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLYNDSEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSTIPKMKEVIGNHA"
     gene            24879..25337
                     /locus_tag="KRQ43_002422"
     CDS             24879..25337
                     /locus_tag="KRQ43_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742772.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            25372..26463
                     /locus_tag="KRQ43_002423"
     CDS             25372..26463
                     /locus_tag="KRQ43_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2742773.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKAGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            26468..26692
                     /locus_tag="KRQ43_002424"
     CDS             26468..26692
                     /locus_tag="KRQ43_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742774.1"
                     /translation="MENIKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            26702..27265
                     /locus_tag="KRQ43_002425"
     CDS             26702..27265
                     /locus_tag="KRQ43_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742775.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            27226..27855
                     /locus_tag="KRQ43_002426"
     CDS             27226..27855
                     /locus_tag="KRQ43_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742776.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            28032..28784
                     /locus_tag="KRQ43_002427"
     CDS             28032..28784
                     /locus_tag="KRQ43_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742777.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            28797..29282
                     /locus_tag="KRQ43_002428"
     CDS             28797..29282
                     /locus_tag="KRQ43_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742778.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYENIMVVDGNSINFIYPVSALQTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            29289..29438
                     /locus_tag="KRQ43_002429"
     CDS             29289..29438
                     /locus_tag="KRQ43_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742779.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(29574..30395)
                     /gene="yidA"
                     /locus_tag="KRQ43_002430"
     CDS             complement(29574..30395)
                     /gene="yidA"
                     /locus_tag="KRQ43_002430"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBH2742780.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMTLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNEAPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            30887..32581
                     /locus_tag="KRQ43_002431"
     CDS             30887..32581
                     /locus_tag="KRQ43_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBH2742781.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSHFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGNIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKISKKLGFEDFVEL
                     GYVRMMRSDYREDMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
BASE COUNT        12808 a         3478 c         5615 g        10688 t
ORIGIN      
        1 tattagtttt gataattcaa attatttaag aaatataggg attttagaaa aaacaggcgc
       61 agatcttaag gaagaagatg atattagcat gagagttgta aattaataga tttttatagt
      121 attataattt attaacaaat taggagaagt tttgaaatta aaaatctaaa aaaaatctta
      181 gtagtcacag ggagggtgac tctaatatct attagtttag tatttgcaaa tactaataat
      241 gatgtaaatg tatgaaaaag taatgaagag caaacaacaa attcatttac aataactggt
      301 tacgaattta tttatgaaaa tgtaccacaa cctataaaat ctgattatga aaaaaatgta
      361 aagaattaaa tataaatcca tctaaagatg atacaatctt tattaatgaa aaatttatag
      421 attcatataa tattaatata gatgattata atattgaacc aaaagcattt attattagat
      481 ataaaaaaga tttaaatcgt tttgatgcta ctggtcctat aagttatagc gtaaatataa
      541 ataccactgt agtaggatat ggacatgtag aaaaagggaa tcctgtgcat ttagtacaac
      601 ttttatgtca acaaataaat ggttctgata ttgatccaga tagtaaattt ggacctgcta
      661 catataatca agtaaaaata cttcaaggaa gacttggtgt aacaaaagat ggtgttgttg
      721 gaaaagccac ttggcaagct gtcggagagc gttattagaa aagaggttgt cgcactaaga
      781 aatagggcga caactttttt atatagaata tattaatcag tatcttagag tctagaaata
      841 ttttacaata aattccatat aactctacca tctatatcct taacattttg acaaccagtc
      901 aaaatcatag tctcacataa ctcattccta accttctcta taaaaaactc cacaccatca
      961 agaccaccgc caaaagaagc agtaacaaaa ggtcttccca tcaaaacagc atcagcaccc
     1021 aatccaagca tcttaactac atcaacacca gtcctaactc caccatcaac aagtattgtt
     1081 atctttccct ttacagactt agctatatct ggaagtacct cacaagtacc aggagtataa
     1141 tcaagtactc ttccaccatg atttgaaaca ataatggcac tagcaccaga ctctacagcc
     1201 atcaaagcat catctacagt cataattcct tttataataa aaggtaattt agtagattca
     1261 accaattctc taatctcatc aattgtctta ggagaaaaag gattttcttg aaattgatta
     1321 ttaataagtc cacaagcatc aaggtctaca ccaactgcaa aagcacctgc ttcttcagac
     1381 aatctaattt tttctattat ctttgaatta ttccaaggct ttataaatac aattccattt
     1441 ccactattat ctttcaacac atctaaatta tccagtaaaa aagtatctac attagtatcg
     1501 ccaaccatag cataaattcc agaattagaa caacctctaa caacaggctc tatgtattct
     1561 ttttcggaaa ctttaccacc catgttcaat agagtacctg atacaggtgc agcgaatata
     1621 ggagaactca tttttctacc aaataattct atggatgtat ctggctttga aacattatgt
     1681 ataactctca tatttatctt tattttttct agactttttc tattttcaat gaaagacgaa
     1741 ccacttcctt taccacccat accaggaaca tctccagcac aagctaatcc attacaaatt
     1801 ttacatactt tacatgttcc attaaagttc tctctagctg attttagtaa gtcattgtaa
     1861 ttcatacaaa atctctcctt tttataatat taaaattgag tattactata ttgaaaatat
     1921 cttaattgta aatataggga tgttattatg atgagctaaa ctagataata catattagat
     1981 attttttatt gttgtagata gttaaattat atcatattag atagtcaaat tttgaaaaaa
     2041 aactaactta tttaagtata cattttgaaa aaattaaaaa agctatatat agatttttaa
     2101 agaaatctat atatagcttt taagtttatg tcaatctttt tttattaatg aataaataat
     2161 atagaataca atatacaaaa aagtttctta aaatgctaag ataatcccca tttacaaagc
     2221 aacatcatta tactgtgtaa atttgaatca acaatgtttt caccatattt caccataaaa
     2281 tcttctaatt gtgtgtcaat aaatgaataa tatccactta tactatcgat gtatgcagtc
     2341 attaagtgta tacattcatc acttttatct ttatacatat atatctcccc ctatatacaa
     2401 tatataaatt tagatactaa atcgtatcat attaaatagt taagtgtgta acatctatgc
     2461 agttatatat ttatatcctt atattaataa ctaaagtgag ttttgacaat agattttggg
     2521 aaactggatg ttcaaagtgt aaacttggat tttaaaatca ttaattaaga tagtgtatag
     2581 gaatatatgt atacataact taattataaa gattataaac aattactttt attaacttta
     2641 tttaagtggt agaataactt ggagattaat aattataagg aggatataat atgagtttat
     2701 acaagtttat atatgatgat aaggaatatt tattaaaaga ggagaactgt agtgctttaa
     2761 taaatgatga agaaaatcca gttcaaggag taagtatttc aaaaataatt gatatactta
     2821 atgaagcaga agaagttgat tttgatgtag aatattatca agaagcatgt ccattatgtt
     2881 tagaaggagt aaaagaaaag aaaaaattct ttcctttttt agaatatcac ttttatattt
     2941 tcagtaaaga tggagaatat gtaataagca atatatctgt tgattataaa ggactatctt
     3001 ttaataaact atcaagggca aataaagttg ataatagtta tattgtaagt gtgataattt
     3061 gtgaaaattg tcaggattat atagttcaga tagaaaattg tatagtttag tgtaaagtat
     3121 gtcttaattt aagagaaatt tctaaattga gacatcaatt tttttcaaaa atagtatgga
     3181 aaattactaa atttatgaga taatgtaagt cggaggtgag ttacaatata tagtaaatat
     3241 ttggaagaga tagatgatac aattttagat tcaatgttta aactaacctt gaatgaaaga
     3301 ttattgacta ataacgattt tgttgaaaat aaaattggtg tagtaaagaa tttaattgat
     3361 tgctataaaa ctgaacaaaa tagtttaatg ttattaaaat caaatttttt gctagcttta
     3421 ttatatggta ttcaagggtt tagtgaaaaa atgaaagagt atattttgat ttcctgtaaa
     3481 tatattgata aatgcttacc caaagattat aaatttttag cacgatttta ttcacaaata
     3541 gctattttaa gtttaaaaaa tgaagatgta aataaggcaa atttatatat ggataaattt
     3601 aatcttattt gtgatgaaaa taattttcta attgaagaaa ttatttttaa atcacaactt
     3661 atttacatta aggcaagtaa gtgtatagaa tcttctgtaa taattaaaga aatagaaaca
     3721 ttgtatataa agataaaaga aattaacgat tttaactgta aaaaaatata tttttttatt
     3781 attggtaaaa tatatttttt gtttttggat gatgctctaa ttgctaaagt aaatttttta
     3841 aaagcaagaa aatatgcaga tttactaaag gatatgcaag tatcttcact atgtaatata
     3901 aagataggtg agtgtgaatg ttcatttgaa aattatgaat gttccataga atatttaaat
     3961 gaagtaataa gcaataaaaa gtatagaaat gtaaatataa ttcaaaaata tagagcatca
     4021 aacaacataa ctaaaatatt aataaagact agaaattatc ctgtagcaat aaataattta
     4081 gcaaaatctg aagtatatct agaaaaaatt aaaaatcaga gcttaaaaga agtagagaag
     4141 tttgatttat ttataagttt agctatgtat tatgcaaaaa gtaatgaaaa atcttttgaa
     4201 caatcaatat gctatttaga tagagctaaa aacatcttaa atatgataaa aaatatagaa
     4261 gaatatacaa tatatgattt agaaataatt tatcatcagg caaagatata ttatatcttt
     4321 ggatattatg acaatgcctt aaacacaaat aaaaaactcc ttgaaaaatc taaaaatgct
     4381 aaaaattata attatgtgaa gttagcatac aagaatatat atttgtgttt tgaaaagatt
     4441 caaaattatg aaatgagtat gaaatacttt aaaatgtatt atgagttaaa aatgatgtat
     4501 ataaaagctc gaaatagaaa ttatatagat tccttaaatt atagacatga gtatatagaa
     4561 acagaaataa ataacatgag aaaagtaaaa cttgatttag ataaaaaaaa atatgttgac
     4621 catttgacaa gtgcatataa tagaactttt ttgaacgatt ttttagaaaa acaagaagtt
     4681 agtgaatatt gcacagcatt tatgatagat gtagattact ttaaagaata caatgatact
     4741 tatggacact ataatggaga tattgctctt aaaaatataa ctataataat aaaaaaatat
     4801 ctaaaaaaag acatgtttat gataaggtat ggtggagaag aatttctgat attatctgta
     4861 tgtaaagatt ataaaaaaag caaaatattt ggaagaaaat tatgtaggat tgtaaagaaa
     4921 tttttaaaca ataatttgac agttagtatt ggcattgata catgtaaaaa tagtagtata
     4981 gatataagag aaataattga aaatgctgat aaagctttat ataaagcaaa ggaaagtggt
     5041 agaaatagat gtttgcatta tcatgatttt aagaattttt aactgttgaa ataggattgg
     5101 tgatttactt gaaaaggagt ttaatagaag atttaaagag aaatataaac aagatagaat
     5161 acgatatgtt gactaaattc tatctaaatt tgacagattt aaactacatc ttggattatc
     5221 acaaagacct tttaaataca aaactagaag ataatagtag agtctatact ttatatttaa
     5281 ttagccttat aaactatata aaaaaagata gagaagcatc atacaactat ttgatagagt
     5341 cattaaagta tattaaaaaa ttgtcattaa aagaagattc agatataata tctaaaattt
     5401 atatttatct tactttatca gctatttcta taagaaaata tgataaggca aataattttt
     5461 atttctcagc aaaaaaagtt ataagacaaa atcatttaaa tgagttgcta gtcttgttaa
     5521 atatgagttt atgtgtagaa ataagtgctt tatatcagac caaaacggat gtaatagctt
     5581 tagtagaaga agtgtctttt tttaaaactt taaaaaataa agctcttgta agtagggcaa
     5641 attatatatt tgggagagtt tatctatatt tatttaataa ctttataaaa agtatggagt
     5701 acctaattga atgtctaaaa ctggctcaag aaaataattt atattctata gaggcttttt
     5761 gtaaatgtat aataagtttg tgttatttag agagtggaaa taatgtagaa gctataaaat
     5821 acataaataa tgtattagat gttgcgcaca gtaagaactc aatatcagta actgaaagag
     5881 tgtctataaa gatagacctt atatgggcat atttaaaaga agatatgaat aaagaagcag
     5941 aagttatttt attaaagact ataaaattaa tgaaagttgt tgaaggtgta tataaggatt
     6001 atttatattc atttatattt ttatattcag ctgaaattga gttaaggaaa gataattgta
     6061 gttttgaaaa ggtaaatacc tatttaattt tatcaaaaaa tatatataaa agttttggcg
     6121 atgtttttat atataattct aaactagatt acatatataa gttgtatgga gatttatata
     6181 taaaatttgg taatatagat gaaggtataa gttgttatat aaaaggttta aatttagtta
     6241 aaaagagttc attgaatctt agaaaaatat ctatatttta tgggctaata gcaaatggat
     6301 atgagctaaa aaaagatttt aaactggcaa tagaatatta taaaagtatg gattggtatt
     6361 ctgataggtg ggaaaaaaat aattcctata aaacatctca agcaattcac aaacaatatg
     6421 aactcagaca aaaacaagag agtttaagat tactagtgga tgataataag aaattagaaa
     6481 atgatatttt aaaagatgga cttactaaac tatataatag aagatatttg gaacagcagt
     6541 tggatttatt taatggaacc agagacaaaa atatggttgc aatactagtc gatatagatt
     6601 gttttaaaag ttataatgat aattatggtc atctagcagg agataaagtt atagttaagg
     6661 taactgatat tataagaagt gtatttatag atattaccga acatataatc agatatgggg
     6721 gagaagaaat tttaatacta gtagattcta tagaatcaat cggtgttgaa gagattgata
     6781 atatagaatt atatattaaa agagttttca aacttcttga atttgagggt attgaacata
     6841 tatattctaa aataaaaaac tatataacta taagtgctgg agtaagtata aaaagatgtc
     6901 gtagtagaaa agatgttgaa atattaattg aagatgcaga taagaaccta tataaatcaa
     6961 aaaaagcagg tagaaatcaa tacattataa tttaaaattg aggtgatttt gttgcgaaaa
     7021 aaaataggaa ttatagcctc tgatattgaa ttaaaagaaa gaatagaaga attatataga
     7081 gaagatgtag aaaatggaac tataataatc gacatactta acctagactt aatggaaaat
     7141 caaggtcgta tacttgttga aaaaggtgcc caagctataa ttggtagagg tggaggttat
     7201 agtttagtaa tagatacagt aaatgtacct gttataccaa tgaatatgaa gtcaactgac
     7261 cttttaagag caatagaaat agcaaagaaa tattctaaaa aagtagtatt gattcttgga
     7321 gacaatgaag tttcttttga ctatgttggc tggagaaatg tcataagtac tgaaataact
     7381 gaagaatggt ttgaatctaa gtatgagata agaagtaaag ttgtaaaata tatagaccaa
     7441 aaagatgaag ttgtaatcgt aggaggaggt ttggcatgtt cttttgcaag gcaatatgga
     7501 attgatagtg tatttgcaac tgctagtgat gaatctataa gagaagctgt agaatattgt
     7561 aaaaaattat tggatacatt aggtgaagaa aagtttaata atgaagtgtt acgaaatata
     7621 cttgatggta taaaagatgg agtaattgct atagatagta atggtagtat aattttgtac
     7681 aatgaaagtg caaaaaacat gcttaaagta gagagaaaat gtgcacttaa taaatacatc
     7741 ttagatgtat ttcctaaaat ggagtggatg ttagattgtt tacatgaaaa agaggatgta
     7801 gaagatagaa agataagaaa tataaataat ctaattgtta atactaggac aacattaata
     7861 aaagttgata atagtactta tggagtttta ggaataatac aagatataac caagctacaa
     7921 aacttagaaa gaaaaataag atttgacttg aatcaaaaag gtctctatgc tagatatact
     7981 tttgatgatt ttttatttaa agataaatta actagagaat ttattgaaga agctaaaaaa
     8041 attggaaaaa gtgattatac aactttactt tatggagaaa gtgggtctgg taaagaaatt
     8101 atagctcata gtatacacaa tataagtaaa agaaaagata ggccttttgt tgctataaat
     8161 tgtgctacta tagcagaaaa tttacttgaa agtgaacttt ttggctatga agaaggtgca
     8221 tttactggtg ctagaaaggg tggaaaaaga ggactatttg aacttgctca tggagggact
     8281 ctttttttag atgaaataaa tagtctatcc tttaatattc agacaaaact attaagagta
     8341 atagaggaac gtcaaataat gagaattggt tctgattata taatacctct ggatataagg
     8401 attatagcag caacgaacga atctttaacc gaaaaaatag ttatgggtac atttagagca
     8461 gacttatttt atagattgag tagtttagag ataaatatac ctcctttaag agacagaaga
     8521 gaagatataa tacctttgtt taacaatttt gtaaatgaag tattaaagga tgatggtctc
     8581 aatggaataa acagtataga tgaaaatttt gttttgacta aagatgaaat ggataagcta
     8641 tataattata gctggcctgg aaatgtaaga gagttaaaga caatagctca aaaatatgtt
     8701 gtgacaggta aaattaaatt gagacaagat agagatttta aaactaaaaa attacttcct
     8761 aactctgaag tagacaaatt taattctgaa acgacagcaa gtgtagaagt ccaagatgaa
     8821 tctataaata taagtaagat aaatgatggt aagataagta tagatataaa agaagtaaat
     8881 aagtatgttg aagaaaaaat aataagtatg ctttttgctc agggactttc taaaaatgaa
     8941 gttgcacaag ttcttggaat aagcaggaca tctttatgga agaaatacaa taaaaatatt
     9001 taaatataat tacatataaa ttattttgaa gtaatgttaa ttttttaaaa caagtgttaa
     9061 gaaaaattaa cattactttt ttgtaaattt ttattttttt agacaggcat atatatttat
     9121 aagaaaaata gttaaaacac ttaatttaat aatgaaaaaa ataataattc taaacaaaat
     9181 caattttaca taaagtggga tttattggca tagtaattgc ttaatatata atgtaagagt
     9241 aaatacaatt ttaggggtga tggtatgagt caaagtatgg ttggtaagca tgcaatgtgg
     9301 ccaaaagaaa atgatgttat atttagcata tctggtagag ctcaagcagc agagaaggct
     9361 tttggtatgg ataatgtaat aaatgcaaca ataggcgctc taatggatga ttcaggaaaa
     9421 ttaataacaa tgaaaactgt atatgaagaa tataaagcat tagataactg tgagataggt
     9481 gcatatgcag ctcttgaagg tcaaccagac tacttagaag cagttaaaaa agtatttttc
     9541 agagattact taccagaagg acatataaga gtattagctt caccaggagg aagtggtgca
     9601 ataaaattag ctgtatggaa ctatactaat gaaggagatg aggtattaac atctgattgg
     9661 ttttggagtc catatgtaag tatagctgaa gaggctaata gaaaagtagt taattaccaa
     9721 ctttttgatg aaaatagaag gtttaatttt gagtcgttca aagaaaaatt tgtaaatata
     9781 gcagaaaaac aaggtagagt ctttacaatt ataaacacac cagcgcataa tccaactgga
     9841 tatagtgttg cagatgatga gtgggataaa atattagact tatcaaaaga agtcgcaaaa
     9901 gataaagaca aaaagataat atttttcgta gattcagcat atattgactt tgcaggtgat
     9961 gatgatgtat gtagaaagtt ttttaagaaa ttttctaatt tgcctgaaaa cgttctcgta
    10021 ttggttggat tcagtatgtc aaaaggattt acagcttatg gtatgagaat gggggctata
    10081 atttgtatat cttcaagtga agatgtagct gaagagttcc attactcatg tgttcattca
    10141 tgtagagcaa attggtcaaa ttgtaataga agtgccatgg cagtattatc taacattgta
    10201 aatgacccta aaaaattcaa agaatatgag gatgaaaaag aaatatacaa aaacatgctt
    10261 actagaagag cagatgtatt tgtagaagaa gctgaaagag taggattaga aattcttcca
    10321 tatatagcag gtttctttgt aagtatacca tgtgataatc caaaagaagt atgtgaagaa
    10381 ttgactaaac ataatttatt tgcagttcca ttaaaaatgg gcttaagatt tgcagtttgt
    10441 gcagtttctg aagataaatg taagaaagca ccaagtatta taaaagaagc acttgaaagt
    10501 ttagaagtaa aaataaataa ttaatttcat tgaacaaatt gggtggacta tgaatttaat
    10561 aattgtagat ggagggaatt ttatatgaaa caattgatga caggtaatga agcaattgca
    10621 cgtggagcct atgaggctgg tgttaaatat gcatctgcat atccagggac tccaagtaca
    10681 gaaatattag aaaatatagc aacatataaa gatgcaatag ttgcagagtg ggctccaaac
    10741 gaaaaggtag cacttgaggc tgctataggg ggttcaattg caggagcaag aacaatggct
    10801 tctatgaaac atgttggttt gaatgttgca gctgatccaa tatttactta tgcatataca
    10861 ggggtaaatg gtggtatggt acttattaca gcagatgagc cgggaatgca ttcatctcaa
    10921 aatgagcaag ataataggat gtatgcaaaa tttgcaaaga tacctttatt tgaaccatca
    10981 actagtcaag aagctaaaga tatgataaaa gaagcttttg aagttagtga aaaatacgat
    11041 acaccagttt tatatagagt tacaacaaga ctttgtcatt caaaaggatt agtggagtgc
    11101 tatgatagag aagaagttga aattaaagag tatgttaaaa atgctaagaa aatggtaact
    11161 gttccagcaa atgctcaaat aagaaggggc gttgttgaag aaagaatgga aatccttaaa
    11221 aaattctcaa atgaaactga tttaaactac tatgaaatga atgatacaaa aataggtgtt
    11281 atagcttctg gtatgtgttg taattttgcc aaagaagttt ttggaaaaaa tgcatcatat
    11341 atgaaactag gatttacaaa tccattacct tatgaaaaaa taaaagaatt tgcagaaaaa
    11401 gttgataaaa tatatgttat agaagaaaat gacccattta tagaagaaca aataaaagca
    11461 tatggaatag attgtattgg aaaagatgta ataccaccat atggagaaat gacaccagat
    11521 gttttaagaa aagctatatt tggaaaaaca aatgatacta tagaatacaa atctgaatta
    11581 gtaacaccaa gaccaccaag tttctgtgca ggatgtccac atagaggatt cttctatgaa
    11641 cttggaaaga gaaaaaattt aatagttggt ggagatatag gttgttatac tcttggattt
    11701 gctcctccat ataatggaat agattatgtt gtttgtatgg gttctgcttt tggaactgca
    11761 catggagctc aaaaagttct taatatgaag gatgataatg aaaaaagatt ggtaggtgta
    11821 cttggagact caacattctt ccatacagga ataaatggac ttttagatgt tgtttacaat
    11881 agaggtaatt ctatttcggt tatattagat aatagaataa ctggaatgac aggtcaccaa
    11941 gaaaacccag gttcagggta tactttacaa ggtgctaaaa ctaaagaagt tgatatagaa
    12001 ggattagtta aagcttgtgg aatagaacat gtaagagtta taaaccctaa caatttaaaa
    12061 gaagtaaatg aagcactaga ttgggcttta gctatagaag atgaaccatc agtaataata
    12121 acaagatggc catgtgtact taaaaaattc tctaaagaag atatagaaga atttaataat
    12181 ccatttaaga ctaagtgtaa agttgaccat gataaatgta taggatgtaa attatgtttg
    12241 aaaactggat gtccagctct atcatttgat aaagagaata agttatcaaa tatagataga
    12301 aatcagtgtg taggatgtgg agtatgtgca caagtttgtc caaaacaagc aatagttaag
    12361 gaggaaaaat aatatgacta agagtatact tttggtaggt gtaggaggtc aaggaactat
    12421 acttgctagt aaattattaa ctatgggatt gatggaagct ggatatgatg taaagatgag
    12481 tgaaatacat ggaatgagtc aaagaggagg ttcagtttcc tcacaagtta gatatggaga
    12541 ttgtgttcat tctccagtta tagaaattgg tggagcagat atattagtat cttttgaaaa
    12601 aatggaagct ttaagatggt tcaattattt aaaaccagaa ggaaaagctt tagtaaataa
    12661 tcataggata gattctatga ctgttttaat cggaggagct gaatatcaag aaagtgatat
    12721 agatgcagag ttaagtagat taaatgcaaa agttataaat gcagctgata aagctgaaga
    12781 actaggaaat tcaaaaataa tgaatgttat tttattagga tgtctagtta aatctatgca
    12841 attagagtct attgattggg aaaaaattat aagtgaaaat gttaaaccaa aatttgttga
    12901 attaaacata aaagctttcc atgaaggtat ggaaatggtt agcaaatagt ttataataga
    12961 tataaataga ctatagaaat taaggtgaaa ggaagaaaat tatgacttac agaatattag
    13021 ccataaatcc aggttctact tctacaaaaa tagcagtata tgatggagaa gaacaaattc
    13081 ttgtgaagac gatagaccat ccagctgaag agattgcaaa atataatact atacaagacc
    13141 agtttgaaat gcgtaaggaa gcagttttga atattcttaa agaaaatagt atagacttaa
    13201 aatctcttag tgcaatagta ggaagaggtg gagttttacc accagtaaaa tcaggagcat
    13261 atctagtaaa tgaagaaatg attgatgtac taagacatag accagtactt gaacacgctt
    13321 ccaatttagg tgctgttgtg gcacatgcaa tatcagaacc tcttggaatc aactcatata
    13381 tttatgattc tgttgcagta gatgagctta tagatgtagc gagaatatct ggactttgtg
    13441 gaatggatag atcaagtgca gggcatgcat taaatactag agcaatggct ttaaaatatg
    13501 ctaaggataa aggaaaagat tataagagct taaacttaat agtagctcac attggtggag
    13561 gagtaagtat ttatcttcat gaaaaaggaa gaatggttga tatgctatct gatgatgaag
    13621 gaccattttc tccagaaagg tcaggaagag tacctgctac aaaattagtg gctgcctgtt
    13681 attcaggtca atattcagaa agagaaatga ctaaaaagat aagaggtaaa ggtggtatag
    13741 tttcatacct aaatactgta gatgctagag aagttgaaaa aatgatagca gaaggaaatg
    13801 aagaagcaaa aattatttat gaagcaatgg cttatcagtt agcaaaaggt attggagagt
    13861 tagcaactgt agtagatgga aaggtagatg ctataattat aacaggtgga attgcatatt
    13921 ctgaaatgtt tacttcaatg gttaaaaaga aagttgagtt tatagcacca gtagaaatta
    13981 tggcaggaga aaatgagttg gaatcacttg cttttggaac tttaagagta ctaaatggag
    14041 aagaagaagc tagaatttat agtgaaaatt aataagaaaa attaaaaatg tttatatact
    14101 aaaaaagtgg tatatccgtt ttttatacac gaaagcttag agtataggtg aaaatgtata
    14161 aaatttggat tgccactttt tataattaaa attttatctt aatctaataa ataattctgt
    14221 aaaatttcgt atttatatat atattttatt ggtatttatt gttattatta ttatgaggag
    14281 tgatttttga tgggaaaaat aagtttaaaa agtatgataa gattattttc aggttttttt
    14341 atatttgcaa tttcttctgt gcttatgatt aatgcacatg taggtcttat gccttgggat
    14401 gtacttcacc aaggtttatc tataaagcta ggcataacta taggtcaggc ttctataatg
    14461 gtaggagttg taattgttat attggatgca gtttttggtg aaaatatagg atggggtact
    14521 ttactcaaca tgacatttat aggaattttt attgatttag taatattttc tggagtgata
    14581 cctcatgcaa gcaacactta tataggtgtg tttatggttg ttataggaat tattttggca
    14641 gctatagcaa gttttctata cttaggtgtt tgtttaggaa gtggaccgag agatgggctt
    14701 atgattgctc ttcagaaaaa aactaataaa tctgtacgtc ttgttagaac aattcttgaa
    14761 atactagcat tagttgttgg gtggttatta ggaggttctg taggtattgg tacgcttgta
    14821 agtgctttag gtttaggata tgtattacaa atagtgttta gaatatttaa atttgacaca
    14881 aagttgctga aacatagatt tattatagat gatataagag aatggaagga aaagagaagc
    14941 aatgaacata aatgtaaatc aagtattgta ataaaaaatg agcagaatta attatgctaa
    15001 aatatatttg tagtttatct aatttatagt aaagtcagga gattttgaaa tggaattatg
    15061 ggatttatat aatgctgatg gaattaaaac aggaaatgtt ataaaaagag gtaattctat
    15121 tgaagaaggt tattaccatt tggcagttga agtgtggatt ttaaatagta actctcaaat
    15181 tttaattcag aaaaggtcta aaagtaaaaa gacattgcca aatatgtggg gaatgacaac
    15241 tggatgtatt gtttctgggg aagatagttt agaaggagca attcgcgaag caaaggaaga
    15301 aatagggata gatataacta aagatgagat gaaagttttt agaagtatga ttcatgaaga
    15361 tactctttgg gatgtatact tagttaaaaa agaatatgat atatccaaag ctattttaca
    15421 ggaggaagaa gtaagtgata taaagtgggt aagcacagat gaaataagac aattactaaa
    15481 agagggtttg ttttttgaat atccagagat gtacgaattg ctatatgaga tagataataa
    15541 taaattaaat atatgatgta gagcagattt cagtataagt aagattattt aaaatgtatc
    15601 ttctctaaat tttaatattg ttttatgaaa attaataagt tatttttagt atttttctac
    15661 ttgttttttg agattaaaat aaaaagggca gtcattataa agtcataaaa atttggggag
    15721 gatttaaact atggaagata acaaaggatt ggcacgtgat agttcaaaat ataaaattgt
    15781 ttctatatct gtcgtagtaa ttattctaat tacattttgg tatatgttaa atatggtgct
    15841 tttaacattt attatgactt ttattttcta taacttgctt gtagccacaa gaaaacgaat
    15901 taagaagttt tcttctttaa atattccaga ttcattgata attatagtgt tatatgcact
    15961 atttgctata ttgttagtat tgattagcta tgcagttgta ccaataatta tagttcaact
    16021 tacagagctg agtagggttt ttagtgattt tgatgtaaat caatttgctc aatctttagg
    16081 accaaaattg tatcctattg tctcaaagct ggattttaat aaatatattt cacaagcagg
    16141 gctacttata gcatcaacag caacaaaagt tggaagtttt ggagtaaata tattattggc
    16201 atttttactg agtttactcc ttttacttga aaaaaatgaa attaaaaatt ttggagataa
    16261 actttctgat agtaagattt cttttattta taattcgctt gtattttttg gaaagagctt
    16321 tgttaaaaat tttggtgaag taatgaaagt acaagttatg attgccttta taaattctgt
    16381 tgtttctatg attttcttag gtttcatggg attccctcaa atatgggctt taggatttat
    16441 gatttttgtg ttgggtctta ttccagtagc aggagttata gtgtctttga ttccattaac
    16501 tgtaatagca tttaatacag gaggaataac aaaggttttt ggagttttac ttatgatttg
    16561 tatagtgcat gcagtagaaa catacatatt aaaccctaag ttgatgtcga atagaactaa
    16621 acttccagtt tgttttgttt ttattatttt acttgtagga gaacattatt taggtgtatg
    16681 gggattacta attggagttc caatatttat gttccttatg gatattctgg gtgttaaatt
    16741 tacttctagg taatatatta aaataataat ttatttttat atataaatta tgaattgttt
    16801 taaaaaagaa cctataaata gacatcatta ataaagacat ctatttgata ggttcaattt
    16861 tgctttgtat aaatactata gaattaaata aaaagaaatt tatttcattt caaaagtttc
    16921 acaacttgca tttctttcat ttatatgaac tttttcagct ttgcaaagtt catttttatt
    16981 gtatttacat tttacagctt cacaatgaat gttatctgta tcaacttggt tagtttcatt
    17041 agaacgacta gttataccag atgtatattt gtcttcaaaa gaagcacaat aagtattttc
    17101 tgtagtagtt gcttgcattc catctacttt tatactacca gcataacaat atccactagt
    17161 attataagca caattagtag cagcacaatt taaattatta tttttcataa ataacctcct
    17221 aagttttatt taaacttatt atgtgaagtt atctaaattt tatacactta tttacaatta
    17281 catttatcac atttaacaac tacatctttg gaagtttccc ttcctaaatt tttattaaca
    17341 tgatacacat caacattttc agttgatcca catatagaac atttaaaatt gttttctagt
    17401 agggttcttt ctttaaataa cttccaatac atagaattga tgtaatcatt ataatttacc
    17461 ttgaggcatg tctcaagaaa gtttatgtat agattgtcta aatctcctgt atttaattct
    17521 gtatattctg gttcaaaata ttcacaacat cctctaaaat caggctttgt atctgaaata
    17581 acacatctaa tatcatatct atagtctagg ctaggcccct taaatgaaag atgtgtgcaa
    17641 aaagaacaag atgtttctgg tagatttttt tcaagttcat gtaatttatt attcataagt
    17701 attcctccaa aaaatttatt ttaagtatat aaatgaatag attattttaa aacttttatt
    17761 tatttatatt agagatttag gataaatatt ccaataagga gtaaatactt aagtatttat
    17821 tactgtatta aataaaaaag aggcaaatct aacttgagat tgcctacttt tttatcattt
    17881 tttaataaaa tttattctaa gtattatttt atttagattt agtcagccaa tttagtatcc
    17941 gctttgcttt ttaactttct accagagcgt acagttaaaa tagcatataa tacagtaaat
    18001 atggcagcta aaacatatga tatatttatg tttaagttaa atccaatttg agcattaaat
    18061 atataactga atataacaaa agaataaaac ataccaggaa ttaagcttat aatataattc
    18121 ttttctttta ttataaggta aactgtaatc attgcaaatg caaatatggc aatagtttga
    18181 ttactccaag agaagtatct ccacaatata ttaaatccag aagcactaag ctttgcaaat
    18241 ataagaatgg ctatgacagg aataaatata cagattgaca atataacacg atgtttcttt
    18301 tccttttggt cataatgaaa gtaatctgca agcattaatc ttaaagatct taaagctgta
    18361 tctccagaag ttattggtaa aacaattaca cctattatag ctatgatacc accaatagaa
    18421 ccaagtaaat ctcttgcaac caaacctatt acatcaggag aacctactaa ttccttaggt
    18481 attcctttat tgtaaatacc catagcagct gcagcccaaa tcattgcaat taaaccttct
    18541 aaaatcatca tattataaaa agtagttttt ccttcttttt catttgaaac tgatcttgct
    18601 ataagagtag cttgagttga gtggaatcca gaaacgatac cacaagcaac tgtaacaaag
    18661 aatgtaggaa taagaggaat accatcagga tgaatacctt tccaatttgc aagacttaaa
    18721 ttagctaaat cataaccttg tgtaaagatt ccaattccaa caccagcagc agataaaagt
    18781 agaatagctc caaatattgg atataccttt cctatgattt tatcaattgg aaagagtgtt
    18841 gcacacaagt aatatagaaa gataagtcca taaactatcc agacaactgg attatttata
    18901 gtcgatttca tatttaaaat ttgagtaaca actaaatccc caggtgtata aataaaaact
    18961 gcaccaacta aaagcattaa aagacaaagg aatatattat agacttgaaa tactttatta
    19021 cctaaaaatc tactgataag agaaggcatt tgtgctcctt tttctcttat actaatcatt
    19081 ccactcatat agtcatgcaa agctcctcca aatacacagc caataggtat tagtatgaat
    19141 gctattggac caaacaatat accttggata ggtcctagaa ttggtcctgt accagctata
    19201 ttaagcaact caattagact atttttccat tttttcattg ggacatagtc tactccatca
    19261 ctttgagcaa gtgcaggtgt ttttctgtca tctgggccaa atactttttc acaataagca
    19321 ccgtataaag cacctcctat tagtaatata gccaagccga ttaagaatgt tgtcataata
    19381 tcaccccatt tataaaattt tttggtcttt gtatacatat tatctaaatg tgtagattta
    19441 tattgaattt aattctggac aacctacaaa ttctataaag tattacaact aatataattt
    19501 cagaaataaa tacatataca taaccatgta cttagtatac aggtatttgg taatattttc
    19561 aatgttatag caataaagaa tataaacaaa attctgataa tattttacaa aaaaattaaa
    19621 aaatataaaa attagtttaa atagatggag aaaaaaggaa aatcaattga gaatataaat
    19681 gtctatatct taacaatatt aagaggttta aaattcttga agaaagaata gtcaagtgat
    19741 ataatgggtt tacaggtgta tatacactag tacatataga aagcggtgca attatggata
    19801 aagatttaac atatcaaatc aaagagctaa agaaagaaaa aaatgcaata atacttgccc
    19861 atttttatca accaccagaa atacaagaat tagcagatgc agttggtgac tcatattatt
    19921 taagtgagat tgctagagat tgtaaagaag aagtggttgt attttgtgga gtaaggttta
    19981 tgggagaaag tgctaagcta ttatcacctg aaaaaactgt attgatgcca gtaagtaacg
    20041 ctgggtgtgc tatggcagat atggtagatg aagaaggcgt gataaaatta aaacaacagt
    20101 atccaaatgc tttggttgta tgttatataa actctacagc taaagttaag gcacattgtg
    20161 atgtttctgt tacatcttct agtgcaatta aaatactaga aaacatagat aataaagaaa
    20221 ttatattcct tccagataaa aatttaggag gatatattgc agaacaattt ccagataaaa
    20281 actttatatt ttgggacgga tattgtaaat accataacaa tataagagct gaagaaataa
    20341 ttgaattaaa agataagtat aaaaatgcag aagtattagt acatccagaa tgtaaaaaag
    20401 aaataagaga tttaggagat tatgtaggta gtacatccgg aataataaaa tatgctacta
    20461 atagtaaaaa caaagacttt ataatagcaa ctgaagaagg tatattacat gaattaaaga
    20521 aaaataatcc taataaaaac ttttatattc ctggtggaaa aatactatgt acagatatga
    20581 aaaagacaac attagaaaat ttatatagta cacttaaaaa tatggaaaat gaagttattg
    20641 tagaagatga aatcatggaa aaggctttaa attcactgct taacatgcac aaattagcag
    20701 aaggatagag ggatagactt atgaatttag aacaagatgt tttaatagtt ggaagtggag
    20761 tttcaggatt atactgtgca ttaaatttag ataaaagttt aaatgtgcta gtagtatcga
    20821 aatcaacaat tgaaaacaac aatacatatc ttgcacaagg tggaatttca actgctagaa
    20881 atattgatga tatagaatcc tttgtagaag atacaatgaa ggctgggcag tataaaaata
    20941 gagttgaagc agttcaagta cttgcagatg aatctataga aaatgtaggg cagatagtag
    21001 aatatggtat gcctttagac aaagaaaatg gagagataga ttacacaaga gaaggagcac
    21061 atagtgtaaa tcgaatagtt catagtaagg ataatactgg agaagttgtt tttaaaactt
    21121 tattaaaaga agctaaaact agagaaaata taactcttat agaagatgca tatcttttag
    21181 atatattaaa agatggcaat aaatgtatag gagctagaat ttttaaatct aaaaaagaga
    21241 ttcatgtttt ttcaaaaata gtagttttag ctacaggtgg aattggtggg ctttttaaaa
    21301 attctactaa tcaaagacat cttacaggtg atggaattgc aatagcttta agaaataata
    21361 taaaaataga aaatttagaa tatattcaaa tacatcctac agccttttat gaagaaaata
    21421 atgaaggtag gagaatgctt atatctgaat cattaagagg agagggagct aaacttttaa
    21481 ataaaaataa agaaagattt gtggatgaac ttcttcctag agatgtagtt tcaaaagcta
    21541 tttttgagca aatggaaaaa gataaattac cttatgtgta tttagatgca acacatttag
    21601 atagtgaata tttaattaat agattttctt ttatttataa tgaatgttta gctagaggaa
    21661 cagatataac gaaagaatgt ataaaggtat ctcctgcaca acattatttt atgggcggga
    21721 tacatgtaga tttggattca aaaacatcta tggaaaattt atatgcagtt ggtgaaatta
    21781 gttgtacagg tgttcatgga gccaatagat tggcaagtaa ttcattactt gaagggcttg
    21841 tattttcaaa aagagcagct aaaaatataa actcagttat agataatgta aaagttaagt
    21901 ttatagatgt accagatatg gatatagata tagaacaggt aaaaaaagaa aataaaatat
    21961 tagtcataaa agaaattgaa agaacaagtg aggattttgg cgatgaatta tttgattatt
    22021 gatagaatga tacaggatgc tttgatagaa gatgttccaa gtgaagatat aacaactaat
    22081 tctattgtgg atgaaaattc taaatctact gtagatttaa tttgcaaaca agatggtata
    22141 atagctggct taggtgtatt taagagagtt tttgagatac ttggtgatgt agatgtaaaa
    22201 ttatataaaa atgatggtga tagagtaaag aatcgtgaaa agatagctgt attaacaggt
    22261 agtactagaa acttacttgt aggagagcgt gtagcattga attatttaca gagaatgagt
    22321 ggtatagcta ctattacaag taggtatgtt gaaaagcttg aaggtacaaa tacaaaatta
    22381 ttagatagta gaaaaacgat acctaatctt agaatattag ataagtattc tgttaaagta
    22441 ggtggaggat gcaatcatag atttaattta tctgatggaa tattgcttaa agacaaccat
    22501 attggggctg ctggtagtgt taagaaggca gttgaattag ctagaaaaaa tacttctttt
    22561 gttagaaaga tagaagtgga agtggaaact ttagacatgg taaaagaagc aatagaagct
    22621 aatgcagata taataatgtt ggataatatg agtttggaaa tggcaaaaca agcagtagat
    22681 attataaatg gaagagccat tgtagaattt tccggaaatg taaatttaga tactatagaa
    22741 gatataggaa aaattggtgt ggatgttgtt tctgtaggag cgcttacaca ttctgttaaa
    22801 gctctcgata taagtatgaa gaatttgaga aatatataag ttttatattg aaataaactt
    22861 aattaaaata gactccttaa atttgtttta taaatttaag gagtctattt tttattcatt
    22921 aaaattaata aaaatataaa aaaatcaatc aataatttaa taaaaataga taaatactat
    22981 atacactttt aataatatag ctaatatcta ttttacagat aaataagaat aaacttataa
    23041 tataattgta tctgtaaaat tttgtaaaat ataaaaagta tagggggaat aaaaatgaaa
    23101 gtagcttata tttttagtag tactaataca cataaaattc tagacaaaat gataatacca
    23161 caacttgaac aaggaactca tggagtagac gttctaggga tgtttttctt tatggataat
    23221 accttatttt tatctaaagg taatccagta ggcgagagac taagtaaatt acatgaaaaa
    23281 actgatatga taataatggc ttgtgaccaa tgtgctatag aaagaggtat agagaataat
    23341 ttggttgatg gagctacaat tggatgtttc ccaaacctat atgcttgttt aggcagtgca
    23401 ggtgtggacc aagttataac gttataaatt agtataggat acaatccata gaaaaattta
    23461 ttttctgtgg attattttaa gtaaaagata aattgtttaa agtaggggat gaacaaatgt
    23521 ctaaaatttt agttgaattt ataaacactt gaccatcttg tgatgaacat ggagtgttta
    23581 taaaaaaaat gtcagaaaag tatgctgata aattggaaat aaaattatat caagcaggga
    23641 aagatttttc gtatataaaa aaatatggga ttataacaaa aggaacttta ataataaatc
    23701 agaaaaagaa atatgataga ttaaataaag atacaattga aagggcaata gtagaagcta
    23761 taaacaataa ttaaaagttt aaaaattagg agtatcaaaa atgaatatat tagaaattgt
    23821 tttaaatgga gttaaagata ctatagtagc ttctatagtt acactgaatg gagcatcagg
    23881 atggcttatg ataagtttta tattggcagg tgtacttcac aatgttttaa ctccaagaag
    23941 gtttcaaaaa caacttggaa ataagaaatt ttcttcttta attaaaagta ctatctcagg
    24001 aatgttttta ccaatatgta gttgtggagt aataccactt ggaataagta tgtattattc
    24061 aggagcatat ttaggaccag tacttgcttt tatgacatca actccaataa taaatccaat
    24121 agctgtagtt ctttgtctag gtcttttagg tcctaaagtt acaatcattt atctaatagc
    24181 tggtttttta gtaccatttt tagtaggatt tttaggaaat tgttttggaa aagaagaatt
    24241 atcactttat aatgattcag aggaagaagt aatagaatta gaagaagaaa aaagaagttt
    24301 tatggaaaat atgattgatg gtcttaaatg gtcttttggt gaattagccc ttactattag
    24361 taaatatgta gtaatgggta tggtttttgc aggatttata acaactattt ttccaaatag
    24421 tataattcaa aaatatttag gaaatccagg tttgctatct cttggaagta tagcaatact
    24481 tgcatgtgtt atgtatgtat gtgctgtagg acatataccg tttatagcag cccttgttgc
    24541 aagtggagca tctcctggta tagcgataac atttctaata gctggagcag ctacaaatct
    24601 accagaactt ataagcatgt ttaaacttat tggaaaaaga actgttatta tatattctgt
    24661 aactttgaca ctgtcctcaa taataattgg atatataaca aatttacttt tagtgaataa
    24721 taattcagta aatttagatg caacaaattc ttcaatacag ttggcaaata aactaatgtt
    24781 aaatatacct gatagttttg agtatgtatg tactatttta attattttat ttgcatttaa
    24841 atcaacaata ccaaagatga aagaggtcat aggaaatcat gcttaaaaag atagttataa
    24901 tatcctgtat agtagttgtg ttaatcattt tatcaaaaat agttgatgat aacatcaaag
    24961 aagatgcttc tattccaaat gtgaataaag aaacattaga atattttaga aaaaattata
    25021 aagaagacat aataacttgt gctgaagaag atttaaataa tgatgggaaa aaagatttag
    25081 tagttatata taaaaaaagc aataattcaa atgaaatggt agtcgtagtt tctgataaaa
    25141 atagccacta tataacaaag ccaataccag cacctataga gaatcaaact ataaccttta
    25201 aaaatattga tgataaagca ccaatagaag taatagtatc agggtctaaa aatggtaatg
    25261 taggatatgc tatttacaga gtagagggta aaaaatttgt tgatttattt ggcgaagata
    25321 tggacaaatg ttgctaaaaa taaaaataat acataaaggt gggaaattta tatgaaatta
    25381 tctaagaaga ttcaagcact aatcttattt ggtgtaatgg gtacatctat attaacagga
    25441 tgtagtagta aaccaaaaga aaaagaagaa gcaaaagctg gaaaagatga ttatacaata
    25501 acagtaggtt attataattg tgaccatatg actgcgggac cagtagcaga atcggcagga
    25561 atatataaag atttaggtct taatgtaaaa actgttggaa atggtaaagt tcctgaagct
    25621 atggcagcag gaaaaatgga tgcaggttac ataggaacta aggggttagt tggagcaata
    25681 cctaagggtt caccaataac aatagcagct aacaaccata ctggtggttc tgaatattta
    25741 atagtttcaa aagatataaa agaacctaaa gatttaatag gtaaaaaaat tgcaacagat
    25801 atgagtgatt tcttatggac aagtgattat ggtccagaaa caggtctacc aactgaccca
    25861 tcaaaatatg aagttgtaaa tatggattca gacaaagata aatatttagc tcttaaaact
    25921 gggaaaattc aagcttttac atcttgtgac ccttggggtt ctgtagctga aaatgacggt
    25981 gcaggaaaaa taatagcatc tactcaatat aaagaaaaag ctaatggcaa agaatataac
    26041 tgttgttcat tctcattaaa caaaaacttt ataaaagaac atccagattt agcaaaaaaa
    26101 ttggttctag cacatacaaa agcaatagaa tatatatata caaatccagc tgaagcagct
    26161 aaaatatttg caaaatatta taatgtagaa gaagaagttg cacttagaac tatctataag
    26221 aagactgttg gagaaggtag aactcttact tggaaagtta caggtgaaga atataaaaat
    26281 aatttacaaa tgtataaaga tttaaaggct ttagatgata tacctaaata tgaagatacg
    26341 attgatacaa gcttattgga ctcttgtgga gctgatgatt ttgacaaatt tataaaagaa
    26401 aaagttaacc cagagtttcc tgaaggtatg agttatgaag actggaaagc aaaggtatta
    26461 taaataaatg gagaatataa aaaatataat aatacttttt atcattattt tgggaagtat
    26521 atttataata ttttttaatt ttgaagataa agaagaaata aaaggaaaat taagaatagg
    26581 ggtatctgat gatacctctg gttttgtaat aaattatatg gtaaatagag actactttga
    26641 aaatataaaa gtaagtgata taatggatat ttttacaatt aatgattgct gagcaagtac
    26701 aatgcagtgg gctctgagtt cagaggaaat agatatagca atcatatgta aagatgctgc
    26761 aaaacaatat gtaaatgtaa atagtggatt tgaaattgtt ggtactgtag ttcaaaattc
    26821 tgatatattt ctattaagtg ataataatcc tgaaaagata ggagtcattc aaaatagaga
    26881 ttaccagtca gaattggtta aaaaatacta caagaatgtg gaagtagctc cattattagg
    26941 gactgcacta gcatatggat tagaaagtaa tttagtagat ggtgttgtaa tagattgcat
    27001 aaagtcaatt gggttagagg gtaaaagaaa atctacaact aaattaggag attatgatac
    27061 ctatgtatta gttgtaagta aagagtttaa aaaaagtaaa gcatatagtg attttataac
    27121 actttacaat aaaagtgttg atgctttaaa gaataaagct acatttaaga aagcattaaa
    27181 agagtacagg aatataagaa atatagatat ggaggaaata agcaattgga aattaaaatt
    27241 tctaaagata aaagcgatag attaactaag aaaaaaactg atggtagtat ggatatttta
    27301 tataaaataa tactattagt tattatattt ttagtctggc attttgcagc aaaagatata
    27361 gggagttctt tgttacttcc aatgccagta gatgtaataa aaggtttctt tttctgtgtg
    27421 acagatgcag agacagtcac taatcttttt ataacattgc agagagtact taaaggtttt
    27481 atgtatgcat tattgtttgg gcttccaata ggatttatta tgggattttc taaaactttt
    27541 gaaagggttt tatctccagt agtagattct gtaaggcaag ttccaataat ggcatgggtt
    27601 cctcttacta tagtatggtt tggtatagga gatggtccaa caatattttt aatagctttt
    27661 tcaggggttt tccctataat tttaaatact attcaaggag taagagcaat atcaaaggat
    27721 tattataatg cagctagaag tatgggagca tcgccaattg tgatatttac aaatgtaatt
    27781 gttcccgcat ctcttccaga tatactaact ggttcaagga ttgctataag tacaggatgg
    27841 atgtctgtta tctgagccga gtttatagct acgagtgccg gtctcggtta ctcaatggta
    27901 caagctcaaa cattaatgca tacagatgta ttaattgggc ttatgatatt tgcagcttta
    27961 ataggattta taatagatag ggtattaaag tttataaata aaatcctttg tagatggagg
    28021 tttgcagatt aatgaagtta agtgtaagag atataaataa gacatttgta aataatagag
    28081 tacatacaaa ggttttagaa gatataagta tggatataga tgatggacaa tttgtctgtc
    28141 ttttaggacc atcaggttgt ggaaaaacaa ctttacttac tataataggt gggtttcaaa
    28201 aatcagaacg tggagatgtt tttataaatg ataaaagagt taaaaaaccg ggcatagata
    28261 gagcttttat atttcaaaat tatgctttat ttccttggaa aactataaga ggtaatgttc
    28321 tatttcctat gaaacagcag aaaataccaa aagaaaaaag agaagaaatg ctagaagaac
    28381 ttttggttat gtcagacttg aaaggaaaag aaaaactgtt tccgcatcaa ttatctggag
    28441 gaatgaaaca aagagtggcc atgataagag ctttagcatg taatccagag gtattactaa
    28501 tggatgaacc attaggagct gtagattttc aaatgagaca aaatttacag gaagagctag
    28561 aacgaatatg gataaagaag aaaataactg cattaatggt aactcatgat gttgatgaag
    28621 ctgtatatat gagtgataga gttatagtaa tgtcgagaga taaaggaaga attattgatg
    28681 atataaatat agatattcca agacctagaa ttagaggaag ccaaaaatat gaagagtaca
    28741 aaaacaaatt aactgatact ttatcaaagt gttatgaagt ttaaagagga gtagacatga
    28801 gtcaaataga aaaatacaat agtttggata atacacaaca gaaaataaga atctctatta
    28861 tggatatgat aatagataaa ggttctagtg ttacacttca agaagtgact gaatatgtaa
    28921 gtaaaaagtt gaatatagaa aaagaatata tagaaaggac actacaatat tttatttatg
    28981 aaaatataat ggttgttgat gggaatagta taaattttat atatcctgta tcagcattgc
    29041 aaacaaatca taaagtaact ttgagagata atagaagttt cagcgcaatg tgtgctatag
    29101 atgctatagg aacctcttgc acattcaacc aagatataaa aataaactct atttgtagtg
    29161 ctacaggtaa ggaaatagaa gtaattataa aaaatgaaaa gattgagtat gtgaataatc
    29221 caaacttaag agtgcttcat ataaatcttg ataagcatct aaattgggct gctagttgct
    29281 gaaatataat gaatttcttc tggacgaaga gtgattttga tgcttggaca aacgaagcgg
    29341 gattatctga tgatgaagat atatattgtt tagatattaa tgaggcaata gtagaatcat
    29401 ataaaatatt taaactcaaa caaaaggtac tatcatagat atacatatat gaaaaactaa
    29461 aaatgacctt tagataaaaa tgataggtaa tatccatact atataaatta gtatagagta
    29521 gggatgtgaa aagtatttaa atctaaaggt atatttttag tttttttaga tgattagata
    29581 gccttattaa gtatatattt atttataacc tttgcaactc cattttcatt attagtatca
    29641 gtaacataat ctgcaatttc ctttatacta ttacgtgcat tccccatagc cacaccaaga
    29701 cctgcatact ttatcatatg ttggtcattt tcttcatcgc caacagcaat agcattttct
    29761 ataggtatat ttagattcgt acataatgtt ttaagagcag ttcctttatt agtagtttta
    29821 cctaaaaatt ctagataaaa aggagcagac cttactatag tatatttatt gaataaattt
    29881 ttaggtagtt gctgtatgat ttcttccaat ctttctggtt catcaactat cataatttta
    29941 cagattttaa tagattcatc aattttatct ttttgtatat atttgacttc tatattattt
    30001 aatttcgctt catgaagtgt atattttcca ggtgcttcat ttggtgtaat taaatttgtc
    30061 attgtattta tgtgtatttt agtcttatat tttttacaaa cgttattata tataaaatca
    30121 aaatcatcta aagtcatttc tacatcatgt atgattttct cacttttaac ttcttgaata
    30181 attgctccat taaagcatat aacataatca ccttcatctg ttaaatttag ttgatttaga
    30241 agttctttta caccaggaag aggtctgcct gttgttataa ctacttttgc cccagccctt
    30301 tttgcctcct gaatggactc aaagacttca ggagtaatcc ttttttgtgt atttaatatt
    30361 gttccatcaa tgtctagtgc gattaatttg tacatatcaa cctccaataa attatatact
    30421 caaatttcct gtgaaaacgt tgacacagct agtgttgaac aaagtttcag tgggaaatat
    30481 ggtttgtttt gtatactatt atatcaagag ataagtaatt tagaaagttt aataatatta
    30541 atttttgata aaaatattac ttatgtgaga tgagaatgta aaaactttgt aatcaataat
    30601 tccaaaattc ttaattacaa ataatggtat cgtttgcatt gttaatataa ataaatgtat
    30661 attatatagt tagaagtttg aataaataga ctgatggtaa tttgttatat tagttagttt
    30721 tgtgttataa aatattgtaa ttccattaat catatgttat tattcaacat gattataata
    30781 taaagaatat ttaatatata taataattta taaaaaagta ttacatagta catgtaaatc
    30841 tatatttata aatacaataa agtaaagttg taaaggagtg ctttaaatga agttttcaga
    30901 gtttaagtat gaaagaccca attataatag tatgaaaaaa gagtttttga gttgtgtaga
    30961 agatataaat aattctcgta attataaaga gcaacaaaaa aatatacata agattaattt
    31021 attaagaaat aaaatagaaa cgttgtcaaa tatagcttcg ataagatata gtacagacac
    31081 atttaataaa ttctacaaag aagaaaaaaa ttattgggat gaatatatgc ctttgtatga
    31141 agaattaaat tcacattttt ataatgctat tgtaaattca aaatttaaat atgatttgat
    31201 aaaagagttt ggagaacaat ttttcacaat agtagagtat tctttaaaaa gtttttctaa
    31261 agaaataata agtgaattgc aggaagaaaa taaattgtgt tcagagtata ctagactttt
    31321 agcttcagct gagataatgt ttgatgggaa tataagaaat ttatctggta tggggaaatt
    31381 catgtattct aagaatagaa aaacaagaga attagcaaac aaagcatatt ataatttctt
    31441 tgaagaaaat gaaactaaat ttgatgacat atttgataaa ttggttaaac ttagagataa
    31501 gatatctaaa aaactaggtt ttgaagattt tgtagagctt gggtacgtta gaatgatgag
    31561 aagtgactac agagaagata tgataaaaaa tgttagaaaa caagtattaa aatatgttgt
    31621 tccaatggcc aatgagcttt atgaaaaaca agctaaaaga attggtctag aatatttaag
    31681 ttacatagat gaaggcgtgg aatttttaac aggaaatgca agtttaaagg gagattcaag
    31741 atacataatt caaaatggta aaaggatgta ttctgaactg tcaaaagaaa caaatgaatt
    31801 ttttgatttt atgttagaaa atgaacttat ggatttagaa acgaaaaaag gaaaaggagc
    31861 tggagggtat tgtacttata taccagatta taagtcacca ttcatttttt ctaattttaa
    31921 tcaaactgct gatgatatag atgtgttaac acatgaggca ggacatgcat ttcagttgta
    31981 tatgtctaga tggattgata tgccagaaat taattttcca acgcttgata gttgtgaaat
    32041 ccattcaatg agtatggaat ttataacatg gccgtggatg gatttatttt ttaaagaaga
    32101 tacagataag tacaaattca ctcacttatc atcttcaatt aaatttatac cttatggagt
    32161 aattgttgat gaatttcaac actatattta caaaaatcct aatgtagata agtcaaaacg
    32221 aaaagaaatc tggagatttt tagagaaaaa atacttacct catagaaaat atggtgataa
    32281 ttctttttta gagagaggtt gttggtggtt taaacaagga catatattta aaaatccgtt
    32341 ttattatata gattatgtat tagctcaaat ttgtgcgtta caattttgga aaaaaatgat
    32401 tcaagataga gatgcaggat ggaaagatta tataaatatc tgtaaagttg gaggaacaaa
    32461 atcattttta gatattgtga gtatgggaaa tttgtattct ccatttgatg atggctgtat
    32521 tgagtctatt ataggtgatg ttaaatcttg gtttgatgaa ataaatgaca gcaaattata
    32581 aaaaattat
//
LOCUS       DAEQJM010000044        32169 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.044, whole genome shotgun sequence.
ACCESSION   DAEQJM010000044 DAEQJM010000000
VERSION     DAEQJM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32169
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.044"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            79..396
                     /gene="flgB"
                     /locus_tag="KRQ43_002432"
     CDS             79..396
                     /gene="flgB"
                     /locus_tag="KRQ43_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBH2742782.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYVTFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            404..808
                     /gene="flgC"
                     /locus_tag="KRQ43_002433"
     CDS             404..808
                     /gene="flgC"
                     /locus_tag="KRQ43_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBH2742783.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            818..1135
                     /gene="fliE"
                     /locus_tag="KRQ43_002434"
     CDS             818..1135
                     /gene="fliE"
                     /locus_tag="KRQ43_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBH2742784.1"
                     /translation="MPITQINNLMQGAKLDNLIGETKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            1160..2710
                     /gene="fliF"
                     /locus_tag="KRQ43_002435"
     CDS             1160..2710
                     /gene="fliF"
                     /locus_tag="KRQ43_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBH2742785.1"
                     /translation="MIASFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDVQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAIPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDEDVDENNQPTNSLINVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSATNNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKAEAKQELEEIKKEGFKKNIIKAVIGVVAVVAIGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            2723..3793
                     /gene="fliG"
                     /locus_tag="KRQ43_002436"
     CDS             2723..3793
                     /gene="fliG"
                     /locus_tag="KRQ43_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBH2742786.1"
                     /translation="MSTEITNVNAFDLSDINESDKKEKIEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNAKANKLLEGISINTSTKPFKHIIKLDVKKILEILRDESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFKDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQDPALAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEAAQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            3786..4517
                     /locus_tag="KRQ43_002437"
     CDS             3786..4517
                     /locus_tag="KRQ43_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBH2742787.1"
                     /translation="MNNKIIKSKKASYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            4521..5840
                     /gene="fliI"
                     /locus_tag="KRQ43_002438"
     CDS             4521..5840
                     /gene="fliI"
                     /locus_tag="KRQ43_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBH2742788.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGIAIG
                     EPPAQKGYTPSVFAILPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRIFE"
     gene            5872..6318
                     /gene="fliJ"
                     /locus_tag="KRQ43_002439"
     CDS             5872..6318
                     /gene="fliJ"
                     /locus_tag="KRQ43_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBH2742789.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIESNLE
                     NLESNYSKYSISKNNDSVQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEQLKEQSTNDEFASMSYLRNRQVL"
     gene            6346..7551
                     /locus_tag="KRQ43_002440"
     CDS             6346..7551
                     /locus_tag="KRQ43_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HBH2742790.1"
                     /translation="MKIQADSYNIIKDIGNRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRRETSKQNVSSDKRENSDNECHLDEDKSNHLEDENTYEKDCSNNNEALHQLLNLLK
                     DNYKKDKDINTILNNLKKLSISDELKQELKLNKNILNKIANQNLELNRASTNNPNDIE
                     NLDIMKLRELLENNASEDIEVISKTTENDTKSIDLYSFDSNRIDTLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKSVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKQNTNDKRNNVVIEDEIKENII
                     DDDRVDLLA"
     gene            7569..8177
                     /locus_tag="KRQ43_002441"
     CDS             7569..8177
                     /locus_tag="KRQ43_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HBH2742791.1"
                     /translation="MYGIATALAGTQVNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMND
                     KLDILLALSNSTLINSALSMATSLIGKEVEVSGEEEEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDANSGEENDSSEQESPEEV"
     gene            8204..9187
                     /locus_tag="KRQ43_002442"
     CDS             8204..9187
                     /locus_tag="KRQ43_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HBH2742792.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMTQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGVIYDGEYKADT
                     GEFIKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GNIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            9200..9403
                     /locus_tag="KRQ43_002443"
     CDS             9200..9403
                     /locus_tag="KRQ43_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HBH2742793.1"
                     /translation="MIRVTDLNGRRYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKVNVGYIRSEK"
     gene            9403..10221
                     /locus_tag="KRQ43_002444"
     CDS             9403..10221
                     /locus_tag="KRQ43_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HBH2742794.1"
                     /translation="MKKTDSLTFIGLILSTVLVLFGAVKGSSSGLKSFFDFASILITV
                     FGSFGALMITFTIDDIKLIKDALQYSFKTMNISKLDLLNQFKTLSKKARREGLLSIES
                     DVMKIQDPFMKKGLELCIDGLEVNEIRSILELEIDSVEETNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLSDLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            10211..10906
                     /locus_tag="KRQ43_002445"
     CDS             10211..10906
                     /locus_tag="KRQ43_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH2742795.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGISMFSTGSSTSEKSPIESVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKADSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            10918..11361
                     /locus_tag="KRQ43_002446"
     CDS             10918..11361
                     /locus_tag="KRQ43_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBH2742796.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQIDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            11376..11750
                     /locus_tag="KRQ43_002447"
     CDS             11376..11750
                     /locus_tag="KRQ43_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliO/MopB family protein"
                     /protein_id="HBH2742797.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYIKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMNKIKDLTKEEILRIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            11751..12416
                     /gene="fliP"
                     /locus_tag="KRQ43_002448"
     CDS             11751..12416
                     /gene="fliP"
                     /locus_tag="KRQ43_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBH2742798.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLKQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            12429..12698
                     /gene="fliQ"
                     /locus_tag="KRQ43_002449"
     CDS             12429..12698
                     /gene="fliQ"
                     /locus_tag="KRQ43_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBH2742799.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMMSLITK"
     gene            12710..14524
                     /locus_tag="KRQ43_002450"
     CDS             12710..14524
                     /locus_tag="KRQ43_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HBH2742800.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGINETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTARMIFFSMDGHHVLIRGIRYSFELIPIGKSFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIIGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSK
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSSIEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIVANLFQVGILFTGETLKPNLSKLNPVSGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIVIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEIKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVLKR"
     gene            14533..16608
                     /gene="flhA"
                     /locus_tag="KRQ43_002451"
     CDS             14533..16608
                     /gene="flhA"
                     /locus_tag="KRQ43_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBH2742801.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVSKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAEIKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            16583..17599
                     /gene="flhF"
                     /locus_tag="KRQ43_002452"
     CDS             16583..17599
                     /gene="flhF"
                     /locus_tag="KRQ43_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HBH2742802.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKLIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQAINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVVNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            17596..18474
                     /locus_tag="KRQ43_002453"
     CDS             17596..18474
                     /locus_tag="KRQ43_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HBH2742803.1"
                     /translation="MIDQAQILRKMAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            18488..19189
                     /locus_tag="KRQ43_002454"
     CDS             18488..19189
                     /locus_tag="KRQ43_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBH2742804.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELNVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            19205..19627
                     /locus_tag="KRQ43_002455"
     CDS             19205..19627
                     /locus_tag="KRQ43_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH2742805.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEIRSNNHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELSLIRSCYKI"
     gene            19612..19797
                     /locus_tag="KRQ43_002456"
     CDS             19612..19797
                     /locus_tag="KRQ43_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH2742806.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            19838..20611
                     /gene="flgG"
                     /locus_tag="KRQ43_002457"
     CDS             19838..20611
                     /gene="flgG"
                     /locus_tag="KRQ43_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH2742807.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNDYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            20632..21393
                     /gene="flgG"
                     /locus_tag="KRQ43_002458"
     CDS             20632..21393
                     /gene="flgG"
                     /locus_tag="KRQ43_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH2742808.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRIYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNIDGLGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            21416..22297
                     /locus_tag="KRQ43_002459"
     CDS             21416..22297
                     /locus_tag="KRQ43_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH2742809.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMIVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVIKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTKKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            22300..22674
                     /locus_tag="KRQ43_002460"
     CDS             22300..22674
                     /locus_tag="KRQ43_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH2742810.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELNTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            22706..24109
                     /locus_tag="KRQ43_002461"
     CDS             22706..24109
                     /locus_tag="KRQ43_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH2742811.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNVKVDDYKNEFLHKSSSNHKIND
                     YNNVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEADVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            24225..26162
                     /gene="htpG"
                     /locus_tag="KRQ43_002462"
     CDS             24225..26162
                     /gene="htpG"
                     /locus_tag="KRQ43_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBH2742812.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITIQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            26550..27680
                     /locus_tag="KRQ43_002463"
     CDS             26550..27680
                     /locus_tag="KRQ43_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH2742813.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDIDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            27907..28929
                     /gene="splB"
                     /locus_tag="KRQ43_002464"
     CDS             27907..28929
                     /gene="splB"
                     /locus_tag="KRQ43_002464"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HBH2742814.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            29111..30022
                     /locus_tag="KRQ43_002465"
     CDS             29111..30022
                     /locus_tag="KRQ43_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH2742815.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYNTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            30037..30453
                     /locus_tag="KRQ43_002466"
     CDS             30037..30453
                     /locus_tag="KRQ43_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH2742816.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(30547..30939)
                     /locus_tag="KRQ43_002467"
     CDS             complement(30547..30939)
                     /locus_tag="KRQ43_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2742817.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            31080..31475
                     /locus_tag="KRQ43_002468"
     CDS             31080..31475
                     /locus_tag="KRQ43_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH2742818.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            31878..32084
                     /locus_tag="KRQ43_002469"
     CDS             31878..32084
                     /locus_tag="KRQ43_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742819.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFNKID"
BASE COUNT        13201 a         3397 c         5912 g         9659 t
ORIGIN      
        1 gccttttttt gtaatatagc aacttcattt tttattaata agcaaaataa ataaaatata
       61 ttttgaggag gagtgagtgt gaatacatat gacattataa aaatgggatt agatgcaact
      121 aatttaagaa gtcagacaat agcaaataat atagccaata taaatactga aggatataag
      181 agacattatg taacttttga agaaacatta aatgatgcta tgccaaaaat agaagaaaaa
      241 acagacaatt ctaaaggatt aagagtggat ggcaataatg tagatataga agaagaaaaa
      301 gtaaatcaag caatggcaac attacaatat aatgctttga taagttttgc aaatggaaaa
      361 atagcaatga ctaaatcaat aataagtggg aggtaattaa aaggtgagtg tgttcagtgg
      421 aatgagaata tctgctagtg gattaacagc agaaagcttg aaaatggata tcatatcgtc
      481 caatgtagct aatataaatg ccacaagagg tccaaatgga gaagcatata ggagaaaagt
      541 tgtttcattt gaagaaaact atgataataa attaggtatg ctaggagtaa aagttacatc
      601 tgttgaagat gataaatcac ctcttaaaga agtatatgac ccatctcatc cagatgcaaa
      661 gccaaatgga tatgtagaat atccaaatgt aaatatattg gtagaaatga cagatttaat
      721 aacagcttca cgagcatatg attctaacgt agatacattg aatgctcaga agtctatgat
      781 atcaaaagct ttggaaatag gaaagtaggg ataaattatg ccaattacac aaattaacaa
      841 tttaatgcaa ggtgcaaagt tagataattt gattggagaa acaaaaccat taactcttaa
      901 taataaagaa gaaaaaaaga actttgaaga tgtaataata gatactatag ataaagttaa
      961 ttttcaacaa gtgacagcag atgatatgaa agaaaaattt ataaaaggcg aagatgtttc
     1021 tatgcatgaa gttatgttaa taggtcaaga agcacagcta tctatgcaat atttaataga
     1081 agttagaaat aagattcatg atgcatatca agaaatgaat aaggtacaaa tttagccttt
     1141 tgaacaggag taataatcaa tgatagccag ttttaaaaat aagattaaag agcaagttgc
     1201 taaatctagg acaaagataa gttctctaaa aaagggaact aaaatagcat taggtatagg
     1261 ggttattgct atatgtttag cgctagtatt tacagcaata tctgcgagca aaaataagta
     1321 tgcagtctta ttttcagaac tagatgttca agatgctgca gatatatcag cagaattaga
     1381 gtctaaaaag atagatacta aggtaaaggg aagtacgatt tatgtaccta gaacagaagt
     1441 tgataagtta aggctggagc tagcaccaag tcttacaggt ggttctaaag gatttgcact
     1501 aatggatgat agttcatcaa taggacttac tgatgaagag tttcagatta agaagcaaag
     1561 aatgatacaa ggtgaaatag aaaaaacaat aaagagtttt ccacaagtgg aagatactag
     1621 agtacatata acatttggag agtcatcagt atttgagaag gaggctattc cagggagtgc
     1681 agcagtttat ttgatgttaa aaccagggac gactttggaa aaaaaccaaa taaaatctgt
     1741 tatggcactt atatcaggaa gtgttacaaa tataccagag aaaaatgttc aagtcattga
     1801 taacaaaatg aatttattat ctgaaggtat tttagaggat gaagatgttg atgaaaataa
     1861 tcaaccaaca aatagtttga ttaatgttga taaaaataag gcatctgaac aagcattgaa
     1921 taaacaatta gaaaagtcta ttttagaaat gctagaacca atatttggta aaggaaaagt
     1981 aaaagccaca gtaaatgctg atttaagttt tgatacagct gaaaaaactg agataaaaat
     2041 tgaccctgat aaagttgcaa taaaggagac aaggtcgaaa aattcatcta aatctgctac
     2101 aaataatgtt caaggtgtag atgctaacat gaataaccaa ggaaataaca atggtactaa
     2161 tacagaagat agtttagatg agagttttga gtatgaaaca ggtaagattg aaactcacac
     2221 tatagttgcg cctggagaac ttaatagatt gacagcttct gttgcaatag atggaaaaat
     2281 agctaaaggt gtacaagctg atgtagagga tattgttaat aatgctatag gtatggatgg
     2341 agcgagggga gatactctta gcgttgtttc aatggtattt gacccagaag ggaaggcaga
     2401 agctaaacaa gagctagaag agattaaaaa agaaggattt aaaaagaaca taataaaagc
     2461 agttattgga gtagtggcag tggtagcaat tggagctatt ggatacttaa tatataagaa
     2521 aagaagtgaa cgagaagata tggattatga agatgaagat tatatttcta aatctgattc
     2581 tgttgatagg aaggataatc ctctattagg agatgaccca gaactgacat tagaggaagc
     2641 tgttaaaatg tatgcagaag aaaagccaga ccaagtaaca gagataataa aaacttggtt
     2701 aaatgagtaa gggggataga aagtgtccac ggaaattaca aatgttaatg cgtttgactt
     2761 aagtgatata aatgaaagtg ataagaaaga gaagatagaa ggtgagggtt taaaaaaagc
     2821 tgctgtatta ttaatgacat taggaccaaa tgtgtctagt gatataataa aaagcttgcc
     2881 tgataaacaa gttcaaaaaa taggtttaga aattgcaaat atttcttcaa tagcttcaaa
     2941 agaaagaaga gaaatcttaa aagagtttgt agagataaat agggcaaaag attatgttat
     3001 agaaggtggg cttgaatatg caagagagtt gttaagcaat gctttaggaa atgctaaagc
     3061 aaacaaatta cttgaaggta tatcaataaa tacaagtaca aagcctttta aacatattat
     3121 aaaactagat gtaaagaaaa tattagaaat acttagggat gaaagtgcac aaactatagc
     3181 tgttttactt gcacatatgg agccagaaaa tggagcagaa gttttatcat acttagattt
     3241 tgatttacaa aatgaagtag ctatgagaat aagctcaatg ggttcaatat ctccagaagt
     3301 aataaaggta attgaaagtt cattagaaga taaattacac tcaataagtg gtgatgattt
     3361 taaggattat ggaggagtgt ctaccttagt tcaaatattg attaattctg atagaaaaac
     3421 agaaaagaat attttgggaa ctattgaaga acaagacccg gctttagcag ctcaaattaa
     3481 atctcatata tttgtctttg aagatattgt caagttagat gatataagta tacaaaaagt
     3541 attaaaagaa gtgactatga aagatttagt atatgcctta aagggtgtgg atgatgagat
     3601 ttcagatgct atatatagaa atcaatcttc tagagcagca gatgcactta aagaagaaat
     3661 ggaaatggtt ggtgtcataa aagttacaca ggttgaggct gctcaacaaa agatagcaaa
     3721 tatagtaaga aaacttgaaa gagaaggtgc cataactatt gtaaggaatt ttggtggtga
     3781 ctttgttgaa taataagatt attaaaagta aaaaagcatc atataaagga gtgctagatt
     3841 taaccataat agataaagtt agagtgggag aatcaaatgt aaataaagaa aatgattgta
     3901 gatttagaga tgaggtaata aaagaagcta tagaatctgc tgagataaaa aagaatgaga
     3961 tattagaaga agcaaaaatg aatgcacaaa atatagaaaa acaagcatat gaaaaagggt
     4021 atagtcaagg tcaaaaaaat ggatatgaag atggatataa agagtcatat gatgaatata
     4081 cccaaaaagc taaagatgaa gcagatttta taaaaaatca ggcagactta atactattac
     4141 aagctaatga gaagatgact gagtacataa aagaaaaaaa taaagagatt gtaagacttg
     4201 ctattaatat ggctagttct gttctaaaaa agcatttcga agatgaagaa tctatgagtg
     4261 atttgttaaa gcaaattatt caagattatg aaggaagtag ttcatttata gtaagatgta
     4321 attctttcta taaagataat atagagaaag agtttgaatt attcaaagag gaaacatcac
     4381 taaaatcaag tgtatttgtt attgcagatg atagtataga taaaggcaat gctatcatcc
     4441 aaaaggaaaa tggaagaata atagttggta tcgattgtgc tatggaaaaa ctaaaagaag
     4501 aattgcttgg tgaataaagt atgtataaaa ctgatatatc tatagatttt gacaaaataa
     4561 ataagaaaat agaaaattta gaactcacta tatcagaagg tagagtaaag aagataatag
     4621 gacttactgt agaagttgaa ggaataaaag cttttgttgg ggagttatgt gttatataca
     4681 atcaagtcaa taaaccagtg aattgtgaag tagtgggttt taaagataaa gaagtcatat
     4741 taatggcgtt gggagagcta acattgatag ctcctggttg taaagttatt tctaagggaa
     4801 tacctttaag tgttatgtgt agcgataatt tactaggtaa agtacttgat ggtcttggaa
     4861 atcctataga caactcagat gctgttttag gagatagata caacttgaac aatgaacctc
     4921 ctgacccaat gaagagaaaa aagatacgaa atataatgga aacaggtgta agagcaatag
     4981 atgcatttac tacttgtggt gaaggacaga gaatagggat atttgcagga agtggagtag
     5041 gtaagagtac gactctaggt atgattgcta ggaatgcaaa agcagatgta aatgtaattg
     5101 cccttattgg agaaagagga agagaggtac tagattttat tgataaagat ttaggtgaag
     5161 agggaatgaa aaaatctgtt gttgtatgtg caacatcaga taaagctcct ttggttaggc
     5221 taaaaggtgc tcttactgct actgcaatag cagagtattt tagagaccag ggaaaaaaag
     5281 taatacttat gatggattca gtaactagat ttgctatggc acaaagagaa gttggtatag
     5341 caataggaga accaccagct caaaaaggat atacaccatc tgtatttgct attttaccaa
     5401 aacttatgga gagaacaggg acatcagata aaggttctat aactgcattt tatacagtat
     5461 tagttgatgg agatgacttt aatgagccaa tagcagatac aacaagaggg atacttgatg
     5521 gtcatatagt tttatctaga gacttggcaa ataagaatca ttatccttct atagatgtat
     5581 tgaacagttt aagcagactt atgaatgaga ttgcttcaaa agaagacata aaaatagcat
     5641 cttttgcgag agatatgctt gctgagtata gagaagcaga agatttgata aatataggtg
     5701 catatgcttc aggtacaaac aaaaaaatag atgaagcaat ctactatcat gagcatatta
     5761 ttaatttttt aaaacaagga ataaatgaaa agagttcttt taatgaaact ataagtagtt
     5821 taagaagaat ctttgaataa acaatttaaa aaaatatttg aataggttgt gatggaattg
     5881 gataaaaatt ttaagtttag attacagaaa gttttagact taaaaataaa agatgaagaa
     5941 gagataaaaa tggaatttgc taagattcaa caaaaaaaaa tagatataga gagcaattta
     6001 gaaaacttag aaagtaatta cagcaaatat tctataagta aaaataatga tagtgttcaa
     6061 aatcaaaaaa taactattaa ctatttgtta gctttaaaca actctataat ggatttatca
     6121 gaagagctgg ataagtcgac aaatgaactt gaaaaagcta gaaagcagct tataagcaaa
     6181 cagatagaga gaaagtcatt agaaaaatta aaagaaaaaa aatatggaca gtattataaa
     6241 gaagaacagt taaaagaaca aagcactaat gatgagtttg caagcatgag ttatttgaga
     6301 aatagacaag ttctataaaa tagtaggaag tgaggatatt attgtatgaa gatacaagca
     6361 gattcttata atattattaa agatattggg aatagaaaaa gctcatctaa gaataaaaat
     6421 ataaaaaata ataaatttga agataatcta tataaggcaa cagaccataa aaaggttaaa
     6481 gatagaagag aaacaagtaa gcaaaatgtt agttcagata aacgggaaaa tagtgataat
     6541 gagtgtcatt tagatgaaga taaaagtaat cacttagaag atgaaaatac atatgaaaaa
     6601 gattgtagta ataataatga agctttacat caattactga atcttttaaa agataattac
     6661 aaaaaagata aagatataaa cactatattg aataatctaa aaaaactaag tatatcagat
     6721 gaattaaaac aagaacttaa gcttaataaa aatatattaa ataagattgc aaatcaaaat
     6781 ttagagttaa atagagctag tacaaataac cctaatgata tagaaaattt agacataatg
     6841 aagttaagag aacttttaga aaataatgct agtgaagata ttgaagtaat tagtaaaact
     6901 acagaaaatg atactaaaag catagacttg tacagttttg acagcaatag aatagatact
     6961 cttaactcaa ataaacagaa agatgatagt tctgatattt tggaaaaact agcaggggta
     7021 aatggaaata agagtggaaa ttttggacaa gtaataaata aaagcgttga tatgaataaa
     7081 attaaaaatg ataatgttaa tttaaaacag atagaatcaa atgtaatgga tgattctata
     7141 aaagctatta agcatatgaa aacaaatgat atacaagaat tgacaattaa attaagacca
     7201 aaagaattag gagatatgaa catacaattg ttaaaagatg gtgaaagtat gagagctgtt
     7261 gtgactgttt tcaacaaaga tgtctttgac tctataaata aaaacatagc agatttaaag
     7321 caacatcttg aacttacaaa tgtaaatata aaagatgtat cagtgcaaat gcatagcgat
     7381 aatacaaata catctgatac ctttgataaa gcatttgaac aacagaatag acaaaataac
     7441 caagaaaaca tgagtaagca aaatacaaat gataagcgta acaatgtagt catagaagat
     7501 gagattaaag aaaatattat tgatgatgat agagtagatt tactagctta gtaaggggga
     7561 agtattgcat gtacggaata gcaacggctt tggcaggaac tcaggtaaac tataggtcaa
     7621 ataatttaag ccaacttgaa agaaatatta atgatattgc caataaacaa gttagaagta
     7681 aaggaaatca gacagtaaca gacaatggga ctccaattat aggacaaggc gatgatgctg
     7741 ataaagattt gtttatgaag attcttgtag cacagatggg taatcaagac ccaatgaatc
     7801 cacaagaccc aacagaatat gtatcacaat tagcacagtt tgcaacttta gaaaagatgt
     7861 cagctatgaa tgataagcta gatatacttt tagccttaag caattccact ctaataaatt
     7921 ctgctttgag tatggcaaca tcattaattg gtaaagaagt agaagtatct ggggaagagg
     7981 aagaagatga aaacattgta ggagtagtaa aatccacata tataaaagat ggggaagtac
     8041 acttagaatt agaagtagat ggaagtgaca aaactgtagg tgttaaatat gaaaaattac
     8101 ttaaaatagg agaggtagat gcaaattcag gagaagaaaa tgactcttca gaacaagaat
     8161 ctccagaaga agtataatat taaatgagaa aagaggtaaa tttatgataa aagcaatgta
     8221 ttcaggtgta agtggaatga aagcaaatca aacaaaacta gatgtaatag gtaacaatgt
     8281 agccaacgct ggaactactt cttttaagaa aagttcagct agaataacag attcatttta
     8341 tcaaactgta ctatatgcaa gtgctccaac agcggcatta gggggaacaa acttaggaca
     8401 agtaggtgta ggtagtaaga tatcaagtat aaataaagat atgacacaag gaaatgtaca
     8461 accaactaat aggccatctg atttaatgat agatggagat ggatatcttc cagtagtaag
     8521 acaaggaaca gttatgtata cgagagatgg ttcttttaat ttagatacag gatttaaagc
     8581 agctgatggt gctttgaaga atattaaagg tggaagactt gtaaatggtg atggatatat
     8641 gttacaaggt gtgatttatg atggggaata taaagctgat actggagaat tcattaaaaa
     8701 gggtgatgct aaaggaaaag agcctattgt aataccactt caaagtataa gtcctaagga
     8761 tggaacagtt caaaatgtac tagagtataa tatatcaaag gatggaacag tagaattttt
     8821 attgagtgat ggtcaaagaa ctcaatttgt ctatgatata cctgatggtg ctaaggtagg
     8881 agatacacct gctggaatag ataaattaaa aggtacaata caaaaagtgc aaacatatgc
     8941 attccaaaat ccagcaggac tagatgcaga aggaggaaac ttattcaagc catcagcaaa
     9001 ctcaggagat ccacaaatag caggagctac aggaaacata atacaagggg caatagaagc
     9061 ttccaatgta gatatagcag aagaatttac agaaatgata atagcaagta ggtctttcca
     9121 agcaaacagt aaaataatat cgacatcaga cgaaatactt caagaaataa taaatcttaa
     9181 gagatagtag gtacatatta tgataagagt aacggattta aacggaagaa gatacatatt
     9241 aaattcagac cttatagtga gaattgactc tgtaccagaa agtaggattc tccttacaac
     9301 aggagaaaaa aatcttgtaa aagagtcagt agatgagata gtagataaag taataaagta
     9361 taaaagaaaa gtaaatgtag gttatattag gagtgaaaaa taatgaaaaa aacagattca
     9421 ctaacattca ttggactaat attatctaca gtattagttt tatttggggc agtaaaagga
     9481 agtagttcag gattgaaaag ttttttcgat tttgcatcta tattaatcac agtatttggg
     9541 tcatttggag ctttgatgat tacatttact attgatgata taaaacttat aaaagatgcg
     9601 ctacaatact cattcaagac aatgaatata tcgaaattag acttattaaa tcaatttaaa
     9661 acactttcta aaaaagcaag aagagaagga cttttatcta tagaaagtga tgtaatgaaa
     9721 atacaagacc catttatgaa aaaagggtta gagttatgta ttgatggcct tgaagtaaat
     9781 gaaataaggt ctatactaga actcgaaata gattctgttg aagaaaccaa taacagatat
     9841 tctaaactat ttaaaacttg ggggactttc gcacctgcat ttggtatgtt gggaactcta
     9901 ataggtttaa tacaaatgtt atctgacctt acatctccag atttaatagc atcgggtatg
     9961 ggaaaagcat taattacgac attttatggt tctttacttg ctaatatcgc tttgaaccca
    10021 attgcatata atatagatga gaagactgaa aaagagattt atgtaaagga aatgatgctg
    10081 gaaggtataa taagcataca atctggggag agcagcatag tagttgagga acgtttagct
    10141 acataccttt caaacaatga gaagctagaa attatgaaat ccaataaaaa tacagaaaga
    10201 gcaatgagta atggcgcgta aaaaaaataa gaaaaaggat gagataaatc cagatgcatg
    10261 gttggctact tatgcagata ctataacact gattcttaca ttttttgtgt tattgtatgc
    10321 tacatcagtt gtagatatgg aaaaatttaa aaacatagca gatgcgttaa aaggtcagtt
    10381 ttctgggata agtatgttca gtacaggttc aagtacaagt gagaagtctc caatagagag
    10441 tgttttagtg gataaaaatg ataagtcaaa tttagaacag gatttaaaag ataaagttaa
    10501 taattctaac ttacaaaata gtgtaacagt caaagatgat agtagaggga ttttactaga
    10561 actagatgat tcaattttat ttgactctgg gatttctgaa ttaaaagcag atagtaaagc
    10621 cactcttaat aaagtatatg acatgataaa gatgatgaaa aataagatag ttatagaagg
    10681 ccatactgat aatgtacctg taaaatcaag tacacatgaa tccaattggg atttatcttc
    10741 tagtagagca gtaagtgttg taagatactt tgtagaagaa aagggcatgg accctagact
    10801 attttcggca acaggatgtg gagagtatca acctttggtt tcaaatgaaa cagcaaaggg
    10861 aagggctgag aatagaagag ttaatatact tataactatt gactaggagg aagaggtttg
    10921 ttcaaaaata aaaaaattat tataattatt ttgatactga ttattttctc agcaggagca
    10981 ggttttttta tattaggaga aggtggaaat aaacaaattg acaagattgc aggtttgttt
    11041 attccaacag ggaaaggcaa agatgaagta aagaccgaaa atcttgactt agaagagatg
    11101 gtattaaagc tagctgatga aggtgtaaga tatttaaaag tatcaataac tgtatcttat
    11161 gattcttcat ataaagatat agaaaaaaat acgcctttaa ttagggataa tattataaat
    11221 tgttttatgg caaaaagggc agatgatttt actgctgata atttaaagaa cataaaagaa
    11281 gaaattaaaa atacattaaa tatacaacta ggtgaaaatg taattcaaaa tatatatttc
    11341 acaaatatag tagtgcaata aaaggatggt aagacatgat actttattta ctaaaaatat
    11401 taatatgtat cccaataatt ttaatattga tagtcttatc tttaaaaatt agccaaggaa
    11461 ctttattaaa aaaatataat gataaatata taaaaatact agatattgta aatataagta
    11521 aaaacaatag cataataatt ttaaaaatag gtgaagaagg atgcattatg gcatcttctt
    11581 cctctagcat gaataaaata aaagatttga ccaaagaaga aatattaaga atagaaaacg
    11641 acattaaaga aagaaatttt aaaattcaag attttaaaat ggaaagaatt aaaaagaaat
    11701 atgatttcag tagatatatt ggaaaattta caaaaaagga agataagtaa atggaactat
    11761 tatcaaaatt acctttggct gatgtaccat atacaagttc aatgcaattg tttttatttc
    11821 taactgcatt aatgttttta ccatttgtaa tgtttatgat gacaagcttt gtcagaatag
    11881 ttataagttt atcatttttg aaatcagcat taggagcaca gcaagcaatt ccaagccaaa
    11941 ttttggtagg gcttgcaata gtattgacaa tatttataat gagaccagta ttaaatgaga
    12001 taaacgaaaa ggcattacaa ccatatatga aagaagaagt tactatggaa gaagctatga
    12061 aggaagcaga gggacctatt aaagaatttt tattaaagca aaccagacag acagatttag
    12121 atttatttgt agaacaggct ggtttgaaag aaaagaaatt aactcgtgaa aatataccac
    12181 tatctgttgt agttccagca tttgctataa gtgaactaaa aactgctttt caaataggtt
    12241 ttttaatata tataccattt ttgataatag accttgttgt ggcaagtgtt ttgatgtcta
    12301 tgggtatgtt tatgttgcct ccagtcatga tatcattacc gtttaagtta ttattatttg
    12361 taatggtgga tggatggaac ttgatagtaa aaacattgat attgggattt ggataggaga
    12421 aaaatagtat gagtgaattt atgataatga gtgttcttaa aaatggcatg tttacaggag
    12481 ctatgattgc agctccagta ctcattgttt ctcttgtagt tgggctttta ataagtgtgt
    12541 ttcaagctac aactcaaatc caagagcaaa ctttgacttt tgtaccaaaa ctaatagcaa
    12601 ttcttttagt agtagctatt ggtggaagct ggatgttaca tactcttatt agctttactt
    12661 cggagatatt caatatgatg tctcttataa ctaaataagt aggatatata tgatttttgt
    12721 atttattaga atagtggcat tctttggaac actaaggata ctatttccag ctggtacacc
    12781 tgctttattt aagtcgctct ttgcaatcat tatatcaata ttgatttcaa gtactatgca
    12841 aattgaatat gcaacaaata tagacaacat tgtattgttt accttatatg gtataaatga
    12901 gaccataact ggcattatgc ttggatatat aaccaatcta tgtttttata gtatcagaat
    12961 ggcaggttct atgatggatc aacagatggg attatcaatg attaatatgt ttgacccaaa
    13021 ttcaatgact cagacaactt taattgataa tcttatgaac tggacagcac gtatgatatt
    13081 ttttagcatg gatggtcatc atgttttaat tagaggcata aggtatagtt ttgagttaat
    13141 tccaataggg aaatcattcg tagataataa tatagattat ataataaaca tatttgtgca
    13201 gtgcttttta actggattca aaatagcaat acctattgta ctttgtctgc ttatggcaga
    13261 ttttatatta gggcttatat caagaagtgt acctcaacta aatgtaatga taattggtat
    13321 gccattaaaa atactggttg gtattgcgtt atttatcata tcaatacctt taattgtcaa
    13381 tcaaataagt catttattaa gtcaaatacc aaagatgtat gagggaactt tcgcactagc
    13441 tcctatgttt tttatgggtt caacagataa aacagaagag gctactccaa agaaaaaggg
    13501 agaacaaaga aaaaaaggta atatagcaaa gagtaaagaa ttacccgttg caatgactct
    13561 acttgcattc actttattag tacctacatt attttcatat gtagtggata cacttaaatc
    13621 ttctcttaat tattttttga gtctagattt ttatatgaat ataaattatt caagtataga
    13681 gaaattagtt atagcaggat taatggattt ttttaagata tttttaccaa tagctattcc
    13741 attcttagtt ttaggtatag tcgcaaacct atttcaagtg ggaatactgt ttactggtga
    13801 aactttaaaa cccaatttat caaaattaaa tccagttagt ggatttaaaa acatgttttc
    13861 tatgagaagt ttgtcaacct taataaagga tacagcgatt atatctattt tggcttacat
    13921 aggatataca ttcttccaag ataattattt agatatatta aagctaggta acatatacct
    13981 gccaacttta atgtacacag ttaaagattt agtatattca atattaagta agatttgtgt
    14041 agctatgata gttatagcag ttgcagatta tgtttatcaa agatacagtc ataaaaagca
    14101 acttagaatg acaaaacaag aagttaaaga tgaatataaa aactcagaag gagacccaga
    14161 aataaaagct aagataaaac aaaaacaaag acaaatttcg tctcaaagaa ccatgcaagc
    14221 agtaccaagt gctactgtaa tagtaaccaa tcccacccac ttatctatag cagtgagata
    14281 tgaaaaaggg aaagaccaag ctccagtagt ggtggcaaaa ggtgcagatt atttagcttt
    14341 taaaataagg gaaattgcaa agggaaatga catacctata atagaaaata aacctattgc
    14401 taggttgtta tataagcaag tagaaataga ccaagaaatt ccagaggaca tgtatcaagc
    14461 ttttgcagag atattagtag cagtatataa aatcaaaaat agatacaaag tcctcaaaag
    14521 gtaggataag taatgaataa gtttaattta aaggaaaata tggacgtaat agtggcattt
    14581 ggtgttgtag ggattgttct tatgatgata gtgccgttac ctacatttat attagatatt
    14641 ttactggcaa ttaacataag tttatctgtg ctaattttac taatgacatt atttacaaca
    14701 aatgtacttg atttatctat atttccaaca gtgttacttg tgacaacact atttagattg
    14761 ggattaaatc tttcatcaac tagattgatt ttaacacagg gatatgcagg tgaagttata
    14821 gaggcatttg gaagttttgt tgtaggtgga aattacgtag taggaataat tatattctta
    14881 attatattaa ttgttcaatt tgttgttata accaatggtt ctggaagagt atctgaagta
    14941 acagctagat ttacgttaga tgccatgcca ggtaagcaga tgagtataga tgcagattta
    15001 aatgcaggag ttatagatga caaaactgct agaaaaagaa gaaaagagct tcaacaagaa
    15061 gcagattttt atggctctat ggatggagca aataagtttg taaagggaga tgccatagca
    15121 ggtcttatag taacagcaat aaacataata ggtggaattg taataggagc tgtaatgctg
    15181 aatatgactc ttatgggtgc agcacagaca tatgtaagac ttactatagg ggatggtctt
    15241 gtaagccaga tacctgctct attaatatct acatcagcgg gtataatcgt aacaagagct
    15301 tctactgatg aaaactttgg tggattagta agtaaacagt taacggcaat accaaaagca
    15361 gtaatgatga ctggttgtgt tctaatcgta cttggtatga tgcctggatt acctaaacca
    15421 gcattttttt cactaggtat aggtgctata gcagcaggtt actttttagg aagagaaaag
    15481 aaagatactt tagaagactt ggagtttgaa aaacctgata tggtaaatcc agataaaaat
    15541 gaagtagaag atgtaacaaa cttaataaat gtagaatcaa tagaagtaga aattggatat
    15601 ggtttaatat ctttagctga tgaatcagca ggaggagatt tacttcagag aatagcatca
    15661 ataagaagac aatgtgcaat agacatgggt atagtcgtgc aacccataag aataagagat
    15721 aatttacagt taaatccaaa ccaatacaat ataaaaataa agggaaatgt agttggtggg
    15781 tatgagataa tgcctaatat ggttttatgt atggacccta tgaatcaagg atttagtata
    15841 tttggaataa agacaattga gcctactttt ggaatagagg cactttggat agaaagtgac
    15901 aaggtagaag atgcagagat aaagggttat acagttgtag attcatccac aatacttata
    15961 actcacttac tagatataat aaaatcaaat gcacacgaat tactgggaag acaagaagtt
    16021 aagactatta tagatgcagc aagagaaaat tatagtgctg tagtagatga attgatacca
    16081 gatttaatga cacttggtga aattcaaaaa gtacttaaaa atctgttaag agaaaaagta
    16141 aatataaagg atagggttac aatacttgaa acgcttgcag accagtctag aaatacaaaa
    16201 gatatagagc ttcttactga atatgtaaga atagccttgg ctagaagtat ttgtaataat
    16261 ttagttgatg atgataagac aattgtagtg gctacattgt ctccagaaac tgaagagttg
    16321 gtatctaata atttacaaag gtctgtaaat ggaacttatc cagcagttga cccagaaaat
    16381 acaaataaaa tatttgagag tatacaagaa gtaatgaaca atgtatattt caatcataat
    16441 ataccagtaa tagtagtatc accaaagata agagctccat ttagaaaatt agttgaaatt
    16501 gtatatccta atttgactgt attatcatta aatgaaatac ctaacgatat taaaatcaaa
    16561 gcagaaggtg tggtgagcat atatgatgac gaaaaagtat acagctaaca caattcagga
    16621 tgctatgaat ctagccaaaa tggaattggg tgacaatatt acattaatag ataaaaaaga
    16681 agtaagaaag tctggaatac aaggtatctt ttcaaagaaa gatattgaac taactattgg
    16741 atgggaaaag agagaaaacg tagaacaaaa agatttaaaa cgagagatag aacaattaaa
    16801 gttaattatt aacaatatgg ggtttgataa taagaatgat aatgatatag ataaaatatg
    16861 taaaaatcta ctaagtttag aattaaatga agaaattgta gaatctataa gaattgattt
    16921 gcaagaaatg aagttcaatg gaattgatac aagcaaaaat ttagtagaaa ttttaaagaa
    16981 aaagattaaa atagaaaatc aagcaataaa tggtaaaatt gctctagtcg gaccaccagg
    17041 agtaggtaaa acgactacaa tagcaaagtt agccgcaaaa ttagtttttg aagaaaataa
    17101 aaaagtagga gtaataacta tagatacata caggattggt gctgtagaac agttgaagat
    17161 atatactgat ataatgaata ttccttttaa aggggtaata agtcccgatg aaatggaatt
    17221 ggcacttgat gagatgaaag attgtgatgt tgtattaata gatacaacag gtagaggcta
    17281 taaaaactct atgcaaatac tagaaatcaa aaatcttata gataaagctg aaactgataa
    17341 tatacattta gttgtgaatt gtacaacaag agaaagtgat acaaaagcaa ttatagattc
    17401 atatagaaat gtgaatttta aaagcttaat aattacaaag ctagatgaaa caataacata
    17461 tggctcaata tttaacataa tgaattatgc acaaaaacca atatcatata ttacaacagg
    17521 acaaaatgtt cctgatgata ttataaaacc taatgaagat aagattataa ggttactatt
    17581 aggagttgaa agtatatgat agaccaagct caaattttga gaaaaatggc aatggaaaaa
    17641 agaggacttg atgagtttat agtagagaat gagaatgtac ctaagataat tacaatagct
    17701 tctggtaaag gcggtgttgg aaagagtaat ctcgctacaa atttgtctat atgcttgacc
    17761 aaacttaata aaaaagttct tatattagat gcagacatag gaatgtctaa tatagatata
    17821 ataatggggg taaatgtaaa agggactata attgatgtaa ttaatggcga aaaaaatata
    17881 gaagatataa tttcacagac taagtatggt gtaaatataa tatctggagg ttctgccctt
    17941 aatcatatag aagactttac agaagctcaa agaaataagt ttatacatag catagaacag
    18001 attcacgatg tggattttat aataattgat acaggagctg gtatgagcaa aagcctattg
    18061 tcatttatat actgtagtac tgaatttttc ttaataacaa ctccagaacc gacatcattg
    18121 actgacgcat atagtttatt aaaagctata agtaattttg gcataaagag aagtgcaaat
    18181 ataataatca atagggtaat tgatttagaa gaagcaaaat ctacatacaa aagaataaaa
    18241 atggttgtgg acaaatttct aaaccttaat ctagaattgt atggatatat aatagatgac
    18301 aaaaaagtaa gtttatgtgt aaaaaaacag ataccattca ttttagaata tcctacaagt
    18361 attgcatcaa aatgtattat agccatagca aagagaatgg taagtcagtc aagagaagat
    18421 attgttgata ataaaagttt tctaagaaag atgtttagta tatttaaaag ctaaggaggc
    18481 gtagttaatg aatagagaag aattaataaa agagaatatg cctcttgtaa agagtatagc
    18541 aagaaaattt tttataccag ggaaaggttt tgaatatcaa gacttagtaa atagtggagt
    18601 cattggattg attgatgcaa taaataaatt tgatgctgaa aagggggcaa agttttctag
    18661 ttactcttat ataaaaataa aatctgctat attagatgaa attagaaatc aaagtccaat
    18721 ttctaaacat aatctaacta aagtaaataa gtataataga gtggtagaaa agttgcaatc
    18781 taaattatta agagagccaa cttcatatga aattgcaaaa gaattaaatg tttcagaaaa
    18841 agaacttcat gatatcgaaa gtaatataga catgttaaat attgtatcat taaactatgt
    18901 aatctttgaa gatacaaatg aaactgtaca agatgtaata agtgatagag aagaggaagc
    18961 tccagaaaat ataatagaag aagaagaaaa gttagagatt ctatctaaag caattagtaa
    19021 tttaaatgaa agagaaaaat taatactttc actgtactat tatgaagatt taaatctaaa
    19081 ggagataggg aaagtgctag gtgtttcaga atcaagagtt tcacaactcc acagaaaatc
    19141 aataagaaac ttaagaaaca agataaaaga acttaaatat tctatataga tggtgattga
    19201 taagatgata caaattatat taatagtagt gtctatttta ataatagtaa ctatagttat
    19261 aaatttacat aaggaatcaa aaaataaaga taacagatac tttgataaaa tatttgagca
    19321 agaatatgaa gcaaatgata gattaataat tgcagaaaaa agaagattct ttttagacaa
    19381 agtacttgct gaaataagaa gtaataatca tataaaagtt tatgaaaatt ataacctaat
    19441 aaaggctaat gaagaaagaa aggaaaacat atttatagaa tcaaaaaagg aagtaagaca
    19501 agaaaatgag ttatctctta aagtgaaaca tcttataagt tcaggttatg atgatgtgga
    19561 aatatgtaag atgctagata ttggaaaggg ggaactgtca ttaataagga gttgttacaa
    19621 aatataagga tattattatg tgataaaaaa gtattcttag gaataggtat tggtatatta
    19681 atatcaactt tatgcataat gctttttagt aataatgata tgagtaaggc agagatagaa
    19741 aaaaaggcca gagcgttagg catgaaatat acaagtgaga tgaaagtttt agaatagatg
    19801 atactgttta gacatttaca aaaaaggagg tcataatgtg ataagaggat tatatacagc
    19861 agtttctgct atgataacta atcaacaaaa gcaaaatgtt gttgtcaata acctagctaa
    19921 tatggataca aatggatata aaagtaaaca acttttgact aaaagttttg atgaattaaa
    19981 gttggagggt tacaataact acgcaaatgg aactaaacaa aagcagatta taggcgatat
    20041 aagtccaggt atttctatgg atgaaactat cacaaatttt aatcaaggac ctataaaaac
    20101 tactgataat aaaatggatg tagctattca aggtaaggga ttttttctag ttagtgatgc
    20161 agctggaaat caattttaca ctagaaatgg gaacttcaga acagacaatc aaggtgacct
    20221 tataacaagt gaagggtatt atgtacttgg gacgaatact gctactggtg ctgtaggtca
    20281 tataaatgta ggaaatcaaa aatttgaagt ggcaaaagat aatacaatat cactagatgg
    20341 aaatgctatg tataaattca atattgtaga ttttaatgac tacaataact taaaaaaaga
    20401 aggagataac ttgtattctg gaggaggagc tatgaaagta aataatgcac ttacaataca
    20461 aagtgcgata gagtcttcta atgtagatat ggtatctgaa attaataata tgatgaccat
    20521 atcaagagaa tatgaggcaa atcaaaagat aattcaggct atggattcta aattagcaaa
    20581 aatagcaagt gagattggtt cagtaagata ggtgatagga ggtgaatttt tatgtacaca
    20641 atgttttata ctagtaaaac agctttatca gcaaatcaaa gtaaactaga tataatatct
    20701 aacaatatag caaattctga ttcaacagga tataaaaaaa taaatatgga atattctgat
    20761 ttagtggatg aagtactaaa tagaccatca tatcctacaa atggcaatga tatatcgact
    20821 ggaacaggag ctaaggcaac agctcccatg agaatttatg aacaaggtgc attggcccct
    20881 acagatagta agagtaattt ggcgatagat ggagaaggat tctttagagt gataagaaaa
    20941 gatggtacat atgcatatac aagaaatggt ggatttaata tagatggttt aggtaagatt
    21001 gtagatgata atggaaatat attagatgtt caatttgatg caggatataa ctataataat
    21061 acgaatatag atagcacaaa cttaacagtt tcaagaaatg gcgagttatt cgtagataat
    21121 aaaaaaatag gaaaaatcaa tttatatcaa cctataggaa ctcaaaattt tatatctgaa
    21181 ggagatagtt tattcgtcgc aactgatgca gcacagatta aacaagttga gaaagtagat
    21241 atagttcaag gctatagaga gaggtcaaat gtttctttac aagaagaatt tgttgactta
    21301 atagccactc aaagagcatt tcaaatgaac tcaaagggaa taaagacagc agatgaaatg
    21361 tggcaaatag ctaataattt aagagctaaa taattatgta aggtgaggaa tattcatgaa
    21421 tgatatgaaa gagtacgatt ttggcaaacc tcagagttat tcaagagaaa atttaacttg
    21481 tttaaatttt ttattagctg aattttgtaa aaaatataaa aactatataa tttatgaact
    21541 taagtgtaat tctagtatga ttgttgatag tatagaccaa gtaaattatc agactttttt
    21601 agatagagta acttcttcat gtgtagtagt acaaaatgca atggaacctg ttatgaaaaa
    21661 cttttctttt agaatagata gaagtgtagc tgatatgtgg attgatataa cttctggagg
    21721 aactggagtt ataaaggata atgatagaga gcttacagaa cttgataaaa aagtgctttt
    21781 acatcttatg gatgatttag taagaaatat gcacttattt gaaggttttg aaaatataca
    21841 agtattggat acacatacac atattaattt accacaatta tgttctccaa ctgcaccagt
    21901 atgcgttgta gatttaaaag tgctaaatga taatgagtat attggaagtg tttctctttg
    21961 ttttccgtat aatggtttag aggctctatt agaaagtata tctgttatag aattttttga
    22021 taatgatgta ggagatgatt cagaggaatt taccaaaaaa atctataata gtgtatctaa
    22081 tatagaatta tcagttattg cagagatagg aaaagtatca attaatgttg aagacttact
    22141 taaactagaa gttggagatg taatagtaac aaataaaaaa ataaatgatt atatagatat
    22201 atttgtagaa aattcaaaat catatacagc aacaccagga tttatatcaa gcaaaaaagg
    22261 tgtaaaaata aatgatgctg ttggaaaaga ggtgtagtta tggacaatag taatcttatt
    22321 tcagatgaag aagcaaagat gttattaaat gataaagttg aaagtgaagt tgatggggat
    22381 gatgagttag ccttagatgt ctctgaagtt aatcgaaata atatacaaag gatacttgac
    22441 cttaagttag aattatctgt agttataggg agaactaaga tgactctaag agatatttta
    22501 aatttacata aaggttctct tattgaactg aatactttag cagaccaaga tgtggaaata
    22561 ctaatagata ataaggtttt ggcttatgga aaagtagtgg tggtagattt aaattttggt
    22621 gtaaagataa caagtatagt aagtgaagaa gacatggtaa aatctcttgt ttagagataa
    22681 catcaattaa tacttaaggc atgaggtggt acttatttta aacttaaatg atataaaaaa
    22741 agatatacta aaactcaata aaaaagactc atgttctcta tataatgaat ctattaataa
    22801 tataaataat aattgtatat caactggatt aaaattttta aaacaagcaa gagatttaaa
    22861 cccagatgat gttgatatat taaatctcac aggtcttgta aacttactaa aatgtaattt
    22921 tgatgatgct gtagaaagtt tctataagag ttcactttgt gaaaaaactg ctctgtgtga
    22981 aaagtatata aacatgctta catctgagga gtttttaatt ttctttgaaa agtacaatca
    23041 acttataagg ttaataaata aaggaatgta taaagaagct atacaagggt ttaaacttat
    23101 aactgaccaa tactgtgatt taatagaacc ttatgagttg cttgccttac tgtatgacaa
    23161 ggaagaagaa tatataaaat ttgatgaatg tttagaagta ttgaagatta ttgataagga
    23221 aaattattta ttaaatcaag aaaataacac attagatatg tataatagtg ctaatataca
    23281 aactaaaagt aatgtaaaag tagatgatta taagaatgag tttttacata aaagtagtag
    23341 taaccataaa attaatgatt ataataatgt aactaaagaa aaaagttcaa gcaaaaacca
    23401 gaaaagttca gattctaata agaaaaaaag tattaaaaaa aataagtacc tatatatagc
    23461 cataatatta ggaatattat tagtaggaca aagtatatat agttcttata agatgaataa
    23521 tttaactgat aaaatatcta aaaataatga aactaaaaat gaagagtcaa tagattctaa
    23581 cttgactaag aaagaaaata atatagaaga aaatgaagat atgagtaagg cttctaatat
    23641 aaataagagt aataaaaaca ttaataaaga ggctgatgta aaatctaaaa aaaatactgt
    23701 agaaaatgaa gatgataaag attctgactt atttacagag gatgaattga tgtctaaggc
    23761 gaatacttta aaatcagaaa aaaaaactaa atcttctata caactatata agaaagttgc
    23821 agatataggt gaaaataaag ggaatacatc tgaagcaact tatcaagttg ctattctcag
    23881 tgaaaagtta aaagactata aaactgctga agaatattat aaaatgtatg tagaaaatta
    23941 ctcagaaaaa gatgcttatt ttgatgaatc ttattataat ttagggatga tgtactataa
    24001 caatggtgat ttaaaaaatt ctaaattgac attaaagaag ttagttaata aggtaccaaa
    24061 tagtatgtat aataattcaa aagtaaaaga aattttaaaa gaagaatagt taaattagat
    24121 aagaaaaata aattatttta ttttaaaata atatgattat aatatattga cataccattt
    24181 taaaaaattt aaaatattaa ttataaaatg aggagggata aaaaatggaa tttgaaaaag
    24241 ggagtatttc aattcataca gaaaatattt ttcctataat taaaaaatgg ttatactctg
    24301 ataaagacat atttataaga gagcttataa gtaatggatg tgatgcagta agcaaacaca
    24361 aaagacttgt atcactagga gaaatatcag aaaataagtc atcagattat aaaattacag
    24421 tatctgtaaa taaaggagaa ggtacactta aatttattga caatggaatt ggtatgactg
    24481 aagaagagat aaaaaaatac ataaatcaag ttgctttttc aggtgctgaa gatttcttta
    24541 ataaatataa ggataagatg gaagagtcaa atgacataat aggtcatttt ggattaggat
    24601 tttattctgc atttatggtg tctaaaaagg tacaaataga tacactttca tatacagaag
    24661 gagcgactcc tgtaagatgg atatctgaag gtggtacaga atacgaaata tctgaatcag
    24721 atgctagaaa tgatagagga actactataa cactatttat tgatgatgat agtaaagaat
    24781 ttttagatga atttactgta agaggaataa taaataaata ctgttctttc ttaccagtag
    24841 aaatatattt agaagatgtt gaaagattag aaagagaagc taaagaagca gaagaaaaag
    24901 ctaaaaaaca aaaggaagat ggaaaagaag agattgtaga tgcaaaagta attgagcctt
    24961 taaacgacac taatcctcta tggttaaaat ctccaaaaga ctgtactgat gaggagtata
    25021 aagagtttta tagaaaggta ttcaatgtat ttgatgaacc tttattttgg atacatttaa
    25081 atgtagatta tcctttcaat ttaaagggta tactttactt ccctaaatta aaaaatgagt
    25141 ttgaactgac tgaaggaaaa gtaaaattat acaacaatca agtgtttgtg gctgacaata
    25201 taaaagaagt tataccagaa tttttacttt tattaaaagg tgttatagac tgcccagact
    25261 taccattaaa tgtatcaaga agtttcttac aaaatgacag ggatgtaagc aaaatttcta
    25321 aacatataat taaaaaagta gctgataagt taaaatctct ttgtaaaaat gaaagagaag
    25381 aatacaataa gttttgggat gatatacaaa tatttattaa atatggttgc ttaaaagatg
    25441 aaagtttcta tgagaaggta aaagaatgta tattattcaa aactattgat gatgagtata
    25501 taacaataca agattattta gaaaaatgta aggacaaaca tgaaaataag gtattttatg
    25561 taagtgataa ggaacagcaa tctcaataca ttaaactatt taaagaatac gacttaagtg
    25621 ctgttgtttt aaactcatca atagatactc attttatttc atttatggaa tataaagaga
    25681 atggagttaa gtttaataga atagatgcag acctttctga tgtattaaaa gataaaaatg
    25741 aaaataaaga tagtgaagaa aacaaagaag agatagctaa gatagaaggt ttgtttaaag
    25801 aagctgttgg agaaagagtg aagaattatt ctgtagaagg attgaaaaat gaagacactc
    25861 cagctatggt attagtatca gaacaatcta ttagaatggc agaaatgcag tcaagatttg
    25921 ctggaatgga tttaggaatg aattttgagg aagaaaaaac tcttgtaata aatgagaaca
    25981 gtccaataat caaaaaattg gtttctctta aagatgatga ggaaaagaaa gataagatta
    26041 cgcttatttg taaccagata gcagatttag ctttactttc taataaagaa ttaaagccag
    26101 atgagttaga ttcatttgta caaagaagta ataagcttat gagtcttttg atagaattat
    26161 aagattgaat ttgaatacat tgaagcaaat ttataaaaag tattcaatat cagtgatgag
    26221 aaagaagtgt ctcaaaatga acttttcagt tcatgaggcg ctttttttat gtgaaattaa
    26281 atttatttta atcatttcaa caatgaaaaa tatatttatc tctattttga gacagaccgt
    26341 tctttatttt tttatctttg gttaattttt aaatatttaa gtaggttcta ataaaaaact
    26401 ctatttagtt aaatatagtt aacttgatat ataataagat aatacatata attaagtaaa
    26461 agattgtttt ttagtttatg tttaaataca taattacact ttgttaaaaa cataaaatta
    26521 ttactaaagt agaaatagga ggttttagca tgaattttaa ttataatttg ccagtaaata
    26581 tcttatttgg gagaggcaga attaatgatg tgggaaaaga agtatctaaa tatggcaaaa
    26641 aagtattgat agtaacaggt aaaaatagta caaagaaaac tggattactt gataaaacaa
    26701 tagatttact aaaagactct aaaatagaat atgaagtttt tgatagagta gaacaaaatc
    26761 ctcttataac tactatatat tcaggcgtag aaattataaa atcaactgga tgtgattgtg
    26821 ttttagggct tggtggtgga agcattatgg atgctgccaa gagtatagct ttttcttata
    26881 aaaacccagg agatttaaat gattatatat ttggaattag acaaggtgaa gaagctttac
    26941 ctataatctt agttccaaca acatcaggta caggtagtga aggaaattgt tttgcagtac
    27001 ttacaaattc agaaactaaa gataaaaaat ctataaagaa gaatagtatg tatgcaaaag
    27061 catcaataat tgacccagaa cttatggtta caatgccaaa gcatataatt gcatcagttg
    27121 gatttgatgc acttgcccat aatatggaag catatctttc taatggaaga aaccctcttg
    27181 cagatgtaca agctatttat gggattgaac ttatatcaga aaacctaata aaggtatata
    27241 atgatgttaa tgatttagaa gcatgggaaa aaataacact tgcaagtact attggaggaa
    27301 tgacgattgg tacagcgggt acagccttgc cacatggaat ggagcatcct gtaagtggtc
    27361 ttagagatgt aatgcatgga aaaggacttg cagcgttgac tcctactatt atagaaagtt
    27421 catgggatat tgatattgaa agatttggta atatttcaaa ggtattagga ggaacttgtg
    27481 cagaagattg ttcagatgca attagaaatt tccttaaaaa aatagattta gatataaaac
    27541 taagtgattt aggtattgaa aaatcagata tagattggtt aactgataat tgtatgaaaa
    27601 tatcagttgc aaatattaag agacatccaa agtattttaa taaggaacaa ataaaggaaa
    27661 tgtaccataa gtctttataa tttgacttta catatttagt tttatataaa aattataaat
    27721 taataataaa aaattataag taattaatag taaaaaaatt gtgtatagaa gttatatata
    27781 taataaactt gtcttaagct tttattttac tttctaataa ataaaggagt ttaaaaaagg
    27841 gaagattaat taagtaatat tttataaaat tcttcgattt aaaaacttta agtagaggtg
    27901 aaataaatgt ttaatcccaa aagaataata ttcgaaaaag gaactttaga cactgatgtg
    27961 ggcaaaaaaa tatacaataa atttagagat aataaagatg tagagataat taatatatca
    28021 tcaaatagga ttaaagaaca cattccaggt gaaaatctat atgaacaata tagaagtggg
    28081 aagcagacta tggtagttgg gattagaaaa agtctgaagt ttcaaacatg taaaccttct
    28141 gctaattatc aactaccact tgtcagtgga tgtatgggaa gatgtgagta ttgttatttg
    28201 aacacacaat taggtgataa accatttata agggtgtttg taaatgtaga tgaaatactt
    28261 gaacagacaa aaaaatatat tgaagataga aagccacagg taaccatatt tgaaggggca
    28321 gctacatcag acccagttcc agtagagcca tatactaatt ctttgaagaa aacaatagag
    28381 ttttttggaa gagaggaaaa aggaagattt agatttgtta ctaaatacag tgatgtggat
    28441 agcttattgg atgctgaaca taataatcat acagaaatac gatttagtat caatactcct
    28501 agaattataa atgaacatga gcattataca gcctctgcaa ataaaagaat agagtcagct
    28561 gtaaaacttg ctagggctgg ttatcagatt ggtttcataa tagcacctgt gtttttatat
    28621 gaaggttgga aagaagagta taaaaatctg attataagta taaaagaagc tttaccaaag
    28681 gattttgata aaaaaattat atttgaagtt atatctcata gatatacaac taaagcaaaa
    28741 aatagaatac tagagattta tccagataca ctattgccaa tggaaaatga ggatagaaag
    28801 tttaaatacg gtcaatttgg atatggtaag tacgtgtatg ataaagaaca attagatgat
    28861 atgaaagagt tctttcttaa ggaaataaat ggagtattta aaaatagttt aataaaatat
    28921 ataatatagc aaatcttacc taaagatttg ctatatttta tttttatata ttttatgttt
    28981 ataataaagc aatgagattt agcactatca tataagaaaa ttaaaaaggg cactatctat
    29041 caagaacatt ttttctagtt ttgatactat aaagggtaag agtaacaaaa atatcaggag
    29101 gagttatagt atgcatgcat gggagtctat tcaaattaca ttggatttaa tagaagcaaa
    29161 tttatcagaa gaaatatcaa ttaatgaatt agcaaataaa gcaaatttat caccatttta
    29221 ctatcaaaga ctatttaaaa gattggtaaa taagactgta atggagtata taaagcttcg
    29281 tcgtcttgca agagcttctg aatacttagc agaacataag aatcgtatac ttgatgtagc
    29341 tttaaatttt ggatttgcta gtcatgagac atttacacgt tcctttaaaa aagcatatgg
    29401 attaactcca gaaaaatata gagcaaatcc agtaaaactc aatcacttta ttaagccaga
    29461 attaatttta aattatgcta tggttgatga aggtgttcca ctgattgcag atgatatagt
    29521 gattgaagtc aatcgtaaga cattgagtaa tccaaggaca tttgttggaa tagaaataga
    29581 agtacctatt tgccagttgg tgggtggtga aacaactgga attgcaatag tagaggaatt
    29641 atggatgaaa cttggaagtc aaagacataa tataccaaat caaattccag gtggaaatga
    29701 atttgctgct ctttatatgg gaaatgcaaa agaaggaaat tgtatgtata tggcaggtgt
    29761 agaggtagag tcaggtacat cagtagaagg atataatact tttgagttgc cagctaaaga
    29821 atatttagta tgtggatttg aggcagaaaa ctttaatgag ttagttaatt cagctgtttt
    29881 taaagcagat aaatttatgg aaagatggat gaagaaacat aatttaacaa ctactgattt
    29941 tgcaattgag atgtattacc ccactacacc tgaagcagca tatctggaac attggattgt
    30001 tccggttcct attgaacaat agaaaggatg atgaatatga attggcaaga tgcgtttttt
    30061 caagatacta aacctacatt tgagcaaatt aatgaattta ttaataatcc attatgggac
    30121 aagttaaata aaactttggt ttctacttat aatgtagaac ctaagcttga atacagtaaa
    30181 tgttcaatgc aaagaggttg gaatgtaaaa tataaaaaaa gaggtaaatc actatgtact
    30241 ttatatccac aagaaggtta ttttaaagct ttggttattg taagtgaaag caatagagta
    30301 gaggttgatt tatttattaa tacttgttgt gattatatca aaaaaatata taatgaggta
    30361 aactttttta atggaagtaa atggctaatg attcaagtag atagtttatt ggtattaaac
    30421 gatatgcttg aactaattaa atttagagct taacatatag aacaggatga atatataagt
    30481 catcctgttt ttatattcaa tcagataaat taatatatag tctataatat gaataattta
    30541 gtaaatttac tttatctttc tacattcttt gcaactaagt ccacatgtgt ttttttcttg
    30601 catattagta gcaccccaat tagcaaattg ttgtaaaata ggcacaatac ttttaccttt
    30661 acttgttaat gtatactcaa cttttggagg aatttcatta tattgtttac gatgaacaat
    30721 accagtagac tctaaatctt ttaatgattg agctagcata gtatttgtaa tgccatccaa
    30781 ttttcttttt atgctactat atctaattgg attttcaact gctaacatac atataatagg
    30841 taatttccac ttaccaccga caatgtctaa tgcataacgg attggacagg ttaattcttc
    30901 aacgttttta gttatatttt tttcagtatt tatactcatt ttaattactc cttagttata
    30961 gtagtatctt ttttatactt tatcagaaaa aactgcatac ttgttttttc tgtattttat
    31021 attaaaatta tatcaaagga taatccttaa tacaagtatt taaaaggggt gtaagaatta
    31081 tgaaagcatt agaatttttg aacaaggcag gagtttatta tttagcaaca gttgatgaga
    31141 acaatcaagc acatgtgcgt cctttaggat ttgttatgga atacaatggt aaacttacat
    31201 tttgcacatc taatcaaaag gatatgttta agcaacttat ttttaatcca aaggttgaac
    31261 tttgttgtat agaccaaaac cttaatactc tacgtatttt aggtgaagca gtatttgtta
    31321 catcaaaaga aacacaagct aaggcacttg aaataatgcc aagtttaggt cagatgtact
    31381 ctgtgggaga tggtaagttt gaaatattct ctattgataa ggcaaaagtt agttgttgtt
    31441 caatgagtgg taaaaagatt gatgtagagc tttaattata attgaatcga catccatagt
    31501 gaaaattaag aaaacgttat tactgaaata ttgatagatt taatttaagt gcaataaaaa
    31561 gatttttaaa taatgaatat gtaaaaattt ttagttatta gatgtgtatt tcaataatga
    31621 tatactattt tgaataatta catactagaa ataagataat taaaatttac tttataatgg
    31681 gatagatttc ttttaaaaaa tattttaact ataattgatt tttatttaat ctgaaaaaaa
    31741 tattatgact ataaaaaatt gctacttatt atttggatat ttttgtatat aaataataag
    31801 tagcatgact ttatacatta ataatgatag aatataaatt aatagataag atataatttt
    31861 aaaaggagtg atataatatg agtaaatata gttctttatg ggaatatgtt aagaaaaata
    31921 atagtcaatc gtttaaatta acttttgaag aaataaaaga tattgctgga atagagatag
    31981 accattcgtt tttgaaatat aaaaaagaat taaatgaata tggatatcaa gtaggaaaaa
    32041 tctctttaaa agagaagact gttattttca ataaaattga ttaagatata aataattaca
    32101 tataataaaa taatttgtat tgacgattat tacaaataaa aataaagtaa atcttatata
    32161 agatttact
//
LOCUS       DAEQJM010000045        31836 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.045, whole genome shotgun sequence.
ACCESSION   DAEQJM010000045 DAEQJM010000000
VERSION     DAEQJM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31836
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.045"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(10..546)
                     /locus_tag="KRQ43_002470"
     CDS             complement(10..546)
                     /locus_tag="KRQ43_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH2742820.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(659..1333)
                     /locus_tag="KRQ43_002471"
     CDS             complement(659..1333)
                     /locus_tag="KRQ43_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBH2742821.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            1536..3410
                     /gene="asnB"
                     /locus_tag="KRQ43_002472"
     CDS             1536..3410
                     /gene="asnB"
                     /locus_tag="KRQ43_002472"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH2742822.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEYVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(3502..4938)
                     /locus_tag="KRQ43_002473"
     CDS             complement(3502..4938)
                     /locus_tag="KRQ43_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH2742823.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVHFTRY
                     IGVDDSIDKYIEKVKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIAQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            5267..5845
                     /locus_tag="KRQ43_002474"
     CDS             5267..5845
                     /locus_tag="KRQ43_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH2742824.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            5884..6462
                     /locus_tag="KRQ43_002475"
     CDS             5884..6462
                     /locus_tag="KRQ43_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH2742825.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLRHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            6548..7177
                     /locus_tag="KRQ43_002476"
     CDS             6548..7177
                     /locus_tag="KRQ43_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH2742826.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            7167..9926
                     /locus_tag="KRQ43_002477"
     CDS             7167..9926
                     /locus_tag="KRQ43_002477"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH2742827.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            10013..11575
                     /locus_tag="KRQ43_002478"
     CDS             10013..11575
                     /locus_tag="KRQ43_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBH2742828.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGVIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDIHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            11576..12712
                     /locus_tag="KRQ43_002479"
     CDS             11576..12712
                     /locus_tag="KRQ43_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH2742829.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            12776..13852
                     /locus_tag="KRQ43_002480"
     CDS             12776..13852
                     /locus_tag="KRQ43_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBH2742830.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHSITGILIPKANSELIENCIEALYSMNLQDMYVI
                     PIIETREFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            13830..15068
                     /locus_tag="KRQ43_002481"
     CDS             13830..15068
                     /locus_tag="KRQ43_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBH2742831.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGVRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELNCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKKHYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            15122..16210
                     /locus_tag="KRQ43_002482"
     CDS             15122..16210
                     /locus_tag="KRQ43_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBH2742832.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            16238..17029
                     /locus_tag="KRQ43_002483"
     CDS             16238..17029
                     /locus_tag="KRQ43_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBH2742833.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKPDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDFSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFKGMSGTEEILSNILDENCLLNI"
     gene            complement(17144..17698)
                     /locus_tag="KRQ43_002484"
     CDS             complement(17144..17698)
                     /locus_tag="KRQ43_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH2742834.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            17893..19095
                     /locus_tag="KRQ43_002485"
     CDS             17893..19095
                     /locus_tag="KRQ43_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBH2742835.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            19152..20132
                     /locus_tag="KRQ43_002486"
     CDS             19152..20132
                     /locus_tag="KRQ43_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH2742836.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            20379..21332
                     /locus_tag="KRQ43_002487"
     CDS             20379..21332
                     /locus_tag="KRQ43_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH2742837.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RVPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAVFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            21322..22278
                     /locus_tag="KRQ43_002488"
     CDS             21322..22278
                     /locus_tag="KRQ43_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH2742838.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKMLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            22275..23030
                     /locus_tag="KRQ43_002489"
     CDS             22275..23030
                     /locus_tag="KRQ43_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2742839.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            23122..24087
                     /locus_tag="KRQ43_002490"
     CDS             23122..24087
                     /locus_tag="KRQ43_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH2742840.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTIKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKTSLPASLEKYKDKKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
     gene            24568..26427
                     /locus_tag="KRQ43_002491"
     CDS             24568..26427
                     /locus_tag="KRQ43_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH2742841.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVC
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICINKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEEILDKEFVYNS"
     gene            complement(26719..27318)
                     /locus_tag="KRQ43_002492"
     CDS             complement(26719..27318)
                     /locus_tag="KRQ43_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH2742842.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(27421..28218)
                     /locus_tag="KRQ43_002493"
     CDS             complement(27421..28218)
                     /locus_tag="KRQ43_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH2742843.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(28331..28436)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(28528..29514)
                     /locus_tag="KRQ43_002494"
     CDS             complement(28528..29514)
                     /locus_tag="KRQ43_002494"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH2742844.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLNEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            29998..31728
                     /locus_tag="KRQ43_002495"
     CDS             29998..31728
                     /locus_tag="KRQ43_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBH2742845.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
BASE COUNT        12321 a         3486 c         5285 g        10744 t
ORIGIN      
        1 tttctacaac tataataaaa tataaaattg atatccaatc aaaaaaataa ctatgaaatt
       61 taatagctta gatatgaatt tttctgtttt tgagttagtt tttataggta gtaaagaaat
      121 gtttatggta atgggataaa acaattcaat accttcttta gtaataaggt caagacacaa
      181 gtgagataga tatcctatta taaacccact ggacaaacat gagaaaacta tattattgtt
      241 agtgaagatt gtcagagatt taaaaaaact ataaataagt aataaggcaa ttagactgtg
      301 agtaaaccct ctatgtctaa acctacttcc aaataatttg tatattaaca taaatttttt
      361 acttatgtaa gaacctctca tatctatatc tggaaataaa gaacctaaat atgcaaaata
      421 aatataaatt ataattaata ctattttata tgcaatatcg tatttaacta ggtacagatt
      481 gtttataaag gggagtatca aaagtgcgaa tatataacct cccctttcat gtgtttcttt
      541 tatcatataa aaatcctcct gaatcgtcac tataaacatt atattggtaa atttagacta
      601 tcttttatta tattatatag caaacataag tttttttcaa aaggatttta atatttaatt
      661 aatcttgaga ttttaaattt ttgtaatttt ctaaagcacc attccaattt actacattaa
      721 accagttgtc aatgtattca tttcttctat tttgatattt taaatagtaa gcatgctccc
      781 aaacatcaag tcctattata ggagttaggt ttttacttac agggctatcc tgatttggag
      841 tagtcataat agataatttc ccatctttag tagctacaag ccaagcccaa ccagaaccaa
      901 agacatctaa agcagatttt tggaactctt gcttaaattt ttcaaaagaa ccaaagtctc
      961 tatcaatagc ttcttttaaa gattcagaag gtatggtttt ttctggcgtc attatatcaa
     1021 aaaagaattt atgattataa gctccacctg cattatttct tacagttgta gcaatatctt
     1081 taggtaaaga atctaaattt tgcaataatt cacataaaga ataattataa agctcaggat
     1141 atttttcaag agcagcattt aatttatcaa cataagcttg ataatgctta tcatgatgca
     1201 gtttcattgt ttctttatct atataaggtt caagtgcatc atatgcataa ggtaatggtt
     1261 taaccttaaa tttgttattt tcaggtgtaa aagcaaatga agttatgcac tgtgagatta
     1321 taaataaaga cataataact ggtattaata tttttttctt cataaaaatc acctcctaat
     1381 atagtatttc tagaaataaa aaaaatatga aatattaaca gataatttat aagaatttaa
     1441 tagcaatttc attttaaatt gaataagttt taaagccaaa gacaaaacta tgaaatatag
     1501 aataagacta aaggacagaa aggaattttg attatatgga cggcaatatt tcaatttatt
     1561 ataaaggtga tatatctaaa aaagaagata ttaaatttaa aataaaagaa tctgtaaata
     1621 atacaagact ttctagtaga atagagtata aggatgagga aaaaactttt gattttgaaa
     1681 gatttaatgt aattgatgct atttatggaa ataaaccatt tgaaaaagat ggaaaagtta
     1741 ttgtttttaa tggaaatata tataactatc atgaaataaa agaagaatta attaaaaaag
     1801 gacacaattt tactacaaat gatgatattg aagtcttatt ggcatcttat atagaatttg
     1861 gtaagaattg tgtacataag attaaaggaa tgttcaactt tataatctat gatagagaaa
     1921 atgaaagtat atttggagca agagatttat ttgggataaa accactttat tatataaata
     1981 aggaaaatgc aataattttt tcctcagagt ataagttttt acttgaatat atgaaaaatt
     2041 taaatataaa tgaaagaagc ttacaaagtt atttttcatt tcaatatgta cttcctgaag
     2101 atactatgat acaaggaata aggctgatac cagcaggtca ctattttagg gtagaaaatg
     2161 gtatactatc tttaaagaga tataataaac ttgagtttag aagtagtaca aaattttttt
     2221 atactaaaaa tcacttaggc aatagagatg tgaatgagga tgatataaga aatatagtag
     2281 tagattcaat agtaactcat atggaagagg agaaagaaat tggaacattt ttgtctggtg
     2341 gaatagattc atctattata actactgtgg cttcacaaat taatccaaat ataaaatctt
     2401 tttctgcagg ctttagtgtc aaaggatata gtgaattaga agtagcaaag aaaacagctg
     2461 ataagttagg tatagaaaat atccagatta atataacaca agatgaatat ataaaatcat
     2521 taccgaatgt aatttattct ttggatgacc ctatagcaga cccttcagaa gtaggtcttt
     2581 atttcttaat taaagaggca ggtaaacatg ttaaagtagc attgtctgga gaaggagcag
     2641 atgaattatt tggaggatat aatatatata aagagtatag tactatgaaa tcagttgtca
     2701 attcacctac ttatattaaa agtatattag gaagagtttc agaacttatg ccaaacataa
     2761 aaggaagaaa ttatctttat agagctacaa caccattaga aaaaagatat ataggaaatg
     2821 caaaagtttt tgaaaacagc gaagtaaaaa gattcttttt taagtataag gaaaagaata
     2881 tatatgaata cctgttgtct aatttgtata gagatgcaca aaaaaataat tacgattata
     2941 taagtaaaat gcaacatata gatgtgaata catggcttca aggcgatata cttcaaaaaa
     3001 ttagcaaact ttctacagct gagcaggttg aacttagagt accattttta tataaagatg
     3061 tatttgatgt agcaaaaaat ttaagaatgg agcaaaaaat aaataagaat aatacaaaag
     3121 ttttacttag agaggcgttt agagaaatag tcccagaata tgttgttcaa aggaaaaaat
     3181 taggatttcc aactccaata agagtttggt taaaagattc tctaggggat attgtaaagg
     3241 aaactattta taattcaaat gtagatgaat ttatagataa aaaatatgca ataaaacttt
     3301 tagatacgca tcttaaaggt catagagata attcgagaaa aatatggact atatttacat
     3361 tttgtctatg gcatcaatta tttattgagc ataaaaatgt cgagtattaa tacttttttc
     3421 aatattaatc agagggcaaa agcatgcaat gttttcaccc tcttgattat tatggaatag
     3481 gataagtaga attttgattg attagtttac tatctcaata aaattattgg caaatatttt
     3541 gacaagatta ctttcaacag ctaaatttaa gttttgtcca tcatcatatc cagcggaaat
     3601 caatcctagt aagtttccaa acatatctaa aagagctcct cctgaactac cactagagat
     3661 tggagctgta aattgtatca tttgaaccgt ttcaaaatca cgaaaagctg agataattcc
     3721 atctgaaact gtattaaaaa gacctaaagg gcttccaatt gcaactattt tttgacctct
     3781 cacaggtttt ttactgactt taacaggtat tggtttgcat tttctatcaa cctttatcac
     3841 agctaaatca taatctgaat ggtattttat aatttggtaa gatgtataaa ctttatcatc
     3901 attttcaaat ctaactaaaa atgaataccc atcattgact acatgaagat tcgtaagtat
     3961 ataaccttca ttatttatta ctactccaga accactctta aacggtttat tttcgttatt
     4021 gcacacaaca atcataacaa cagaagctga taactttgca aggtcttcat aagaaagttc
     4081 tacttcctca tcttgtgcaa tttttttaga tgttagattt gtgttattaa gtgtattttt
     4141 agagttaggt ttattcgtag taggagaagt cttattggta ttttcactgt aatttatatt
     4201 tgtaatatgc ctttcaaaag gtatttctaa tatatttgga gttttcctag aaagttcaaa
     4261 tagagtagaa aattttgaac attcaggata taaatcaaga atatctttat ttggatttat
     4321 atataaaata tcacacccaa gttgtgataa aaaatataag aaaaaaagtt cttgcctttt
     4381 aatatttcca aagtatacta tctttggtga aatagtagtc ttcaccttgt tataaaataa
     4441 tttaggtaga aaatagtcca tccaacacaa aagtttaact gcaaagtttt tgatgataga
     4501 ggatgtacaa tttggcatac ttgtggaaaa taaatctaaa gtatttttaa atgcaatctt
     4561 tttagtccaa tttaaagtgt cattttctat tttacatgga aagtcgatat tatataaatc
     4621 ccaactgtta aacttagaac tatcataaat attaaaaatt ttaagcatct tatctgtttg
     4681 ttctttgtca aaatttattt ttagattgtt taatctaata tagggaattg taggattatt
     4741 aaaaaaataa gtatctatat ttttaacttt ttctatgtat ttatcaattg aatcatcaac
     4801 acctatatat cttgtaaagt ggacttcttt aatatatgaa gaactcttat ttttataggt
     4861 agtatcagat ataaattcaa ttagaggttc agttgacttt tttattgaaa tctttaatgg
     4921 tttaatagta caaatcatat tttttctcct ataataagat gatataatct attataaaac
     4981 aacttaaaac aatatagtac aataattttg tagtttcaaa ataaaatatg tacttgttta
     5041 tataaatgat atataattac gtattaaaca tagcttttat acatttaata aagtatgtaa
     5101 aatctatgta aaaagtaaga aatataaaca tttttttaat tatattttaa aaatatcaag
     5161 caagttttct tcacaaatga ataaaaaatg ttataatatg attaaagaaa aagataaata
     5221 attagcaaga tttgtttagc taaaattaac aagggagcga taaattatgg gtataacatt
     5281 atcaaaaggc caaaaggttg atttaactaa aggaaatcca ggtcttaaaa atattttagt
     5341 aggtttagga tgggatacta acaagtatga tggtggattt gactttgatt tagatacagc
     5401 agcattttta acaggagcaa gtggaagtgt tactaatgat ggagattttg tattttacaa
     5461 caatttaaaa catacatctg gagcagttga gcatctagga gataacagaa ctggcgaagg
     5521 tgatggagat gatgaacaaa tagttgttga tttatctaag attcctggag aaataagcaa
     5581 gatttctttt actgttacaa ttcatgatgc gacagaaaga agacaaaatt ttggacaagt
     5641 aagtaattct tatataagaa tagtagataa agacacaaat gaagagttaa taaagtatga
     5701 attaggagaa gattttagta tagaaacagc tatagtagta gctgaaatat ataagcacaa
     5761 tggagaatgg aagtttaatg cactaggttc tggttttgaa ggtggtcttg ctgcattatg
     5821 tggaaacttt ggaataaact tataatttca actataacaa taaactaaag ggggatattt
     5881 tccatggcta tagtattaaa aaaaggacaa aaaatcgatt taactaaggg aaatccaggt
     5941 cttaaaaata taaaacttgg actaggatgg gatacaaatt catttgatag tggctatgat
     6001 tatgatttag atgtaagtgt tttcatggtt ggagaatctc aaagagttga aaaagatgaa
     6061 gattttatat tctacaataa cttaagacat ccatctggag cagttgaaca cttaggtgat
     6121 aatagaactg gtgaaggtga tggagatgat gaggaaatat tagtgaattt agagacaatg
     6181 ccaaagcata tacaaaagat agctgtaaca gttacaatat atgaggctgc tgaaagaaga
     6241 caaaattttg gacaagtaag caactcatat ataagagtat taaattctga aaatgatgaa
     6301 gaaatattaa gatatgactt aggtgaagaa tttagtatag aaactgcaat tacagtatgt
     6361 gagatatata agtataatgg agaatggaag tttagtgcag ttggagcagg atttgaaggt
     6421 ggcttagaag cactttgtag aaactatggc ttaaatgttt aatttaagca atataatata
     6481 ttaaatataa ataacctata caaataatgt ataggttata ttatataaaa ttttgtggag
     6541 gtttagtatg tcgattaatt tatcaaaagg tgataaaata gatttaaaaa aatctaaccc
     6601 aggactgagt aacatacttg taggtctagg atgggaccct gtgcaacaat ctggaggagg
     6661 tttttttaaa tcgttatttg gtggaggaca agctgatata gattgtgatg catctgtatt
     6721 tatgcttaat caagaaggta aattaagtgg aataaaagat ttaatttatt ttggaaatct
     6781 aaaaagtgcc tgtaaatcag ttttgcatac aggagacaat ctaactggtg agggtacagg
     6841 tgatgatgaa caaatcctag ttaatttgga taaagttcca tcaaatattc ataaattatt
     6901 gtttgtagta aatatataca attgtgtaga tagaaaacaa cactttggaa tgatagaaaa
     6961 tgcctatata agagttgaag accaaggtaa taagaaagag atagcaaaat acaatctatc
     7021 tgataattat tctgaaaaaa ctactcttat agtaggagct atatatagaa aagatggaag
     7081 ttggcaattt aaagcaattg gtgaaggaac aaaagatgcg ggtcttaaag aagtaatgca
     7141 aaatttagac aggattgagt gtgcatatgg aatttaataa tgatatcaaa tattataatg
     7201 tagataaaga agaagttaca aaagacttat ctgttaatcc tgaaaaaggt ttatcagaat
     7261 cagaagtcaa gactagaaga gaaaaatatg gtttgaatga atttactcca aaagaagagg
     7321 gtagtttttg ggatgattta aaagaaagtt taagtgaacc aatgatagtt atcttgatta
     7381 ttgcagcagt agtaagtgca gtaattgggg aaactcatga tgcaataggg attgtaggtg
     7441 ctatagcaat aggtatagca ataggtatga ttacagaagg tcgttctaag aaagcagcag
     7501 aggctctttc taagttgact gaaaacatag aagtaaaagt attgagagat ggggaagtac
     7561 atcaaatttc taagagtgaa ttggtaccag gtgatatagt atatattgaa actggtgaca
     7621 tggtacctgc tgatggtaga cttatagaaa gtataaacct taaaattaga gaagatatgt
     7681 taacaggaga atctgatgac gtatctaaaa agtgtgatgt agtagtttct atggaagaga
     7741 tagaatctaa aggagcagta gtagtacagg agccaatacc tgcaaaacag ataaatatgg
     7801 tgtttggtgg tacacttgta gcttatggta gaggagctct agttgtaact tcaattggag
     7861 ataatagtga aatgggtaaa attgctcaaa acttatcaga aacagatgag caaactccac
     7921 ttcagataaa acttggaaat ttaggtggtt tgatagccaa agtttctagt gcagtagcag
     7981 gattactatt tatatttatg gttttccaaa tgataagtaa gaatgtatta aatgtagata
     8041 tgtctggaat attaccgttt ttagaatcaa tagacccagt taaaacagca tttacagtat
     8101 gtgttgcgtt gatagttgca gcagtgccag aaggtcttcc aactatgata aatatgacac
     8161 ttgcaataac aatgcaaaaa atggctaaaa taaatgcatt ggttaccaaa aaagaagctt
     8221 gtgaaacgat aggttctgtt tctgtaatat gttcagataa aactggtaca ttaactgaaa
     8281 atagaatgac tgtagaagtt gcatatgttg atggcagata tattgaaagt tcagaagagg
     8341 aaataaatag ttattttgaa gaaaactgta tgataaactc tacagctgat gtagagcaca
     8401 atgatggtga tattaagtat ttaggaagtg ctactgaatg tgcattgctt ttatattaca
     8461 aaaacgtaga ttatagacaa gttagaaaaa attctaatat agtagctcaa aatcctttta
     8521 cttcagattc aaagagaatg acttctgtta taggtcaaga taatcatcat gtactattat
     8581 caaaaggagc accagaagtc ttacttgaat tatgttcaca tattcaaaga ggaaaagaca
     8641 tagttccatt aactgaaaat ataaaacatg agattttaga agaaataaag aaattgcaaa
     8701 taaaatcaat gagaacttta gggtttgcat ataaagaaat ctcacaagct gaagaagaag
     8761 cagcagtaac tgctgaaagt gatgctatga atgtaagtgc aatggaaaat aatttagtat
     8821 ttagtggttt tgttggtata agagacccac ttagaaaaga tgttatagag tctgtaaata
     8881 cagcaaataa agctggtgtt tctgtaaaaa tgcttacagg agataatata aatacggcaa
     8941 gagctatagg tgaagagtta ggcctattaa aaaataatat gagagtggtt gaagcttcat
     9001 atatagatac tttagatgat gaagaattaa aacaagagat acaaagtatt tcaatcgtgg
     9061 caagaagtaa accagatagt aaaatgagaa tagtttcagc tctgcaaaag agcggggatg
     9121 ttgttgcagt aacaggtgat ggtataaatg atgctccagc actttcaaaa gcagatgttg
     9181 gtatagcaat gggtatatct ggtacagagg tatctaaaaa cgcagcagac ataattttaa
     9241 ctgatgatag ttttagtacc attgtaaaag gtattaaatg gggtagagga atttatgata
     9301 acttccaaag attcgttcaa ttccaattaa ctgtaaatgt aattgcattt ttagtggcta
     9361 taatatctca agttatggga caagagatgc catttactac aatacaatta ttatgggtaa
     9421 acataattat ggatggacca ccagcactag cattaggttt agagccagtt agagaccatg
     9481 tgttaaatag aaaacctgtt gatagaaaag ccaatataat ttctaagtca atggtgtata
     9541 caatagtatt aaatgcattt tatataacag caatactaat gttacaatct acatttaatt
     9601 tcttaggagt tgatgaagct cataagggaa cagtaatgtt tgcgttattt gcttttagcg
     9661 cactgtttaa tgcatttaac tgtagagagt ttaatgcaga tagtatcttc cctaatttta
     9721 cacataacaa attagcacta caaataatag tgttgacagg aattgcacaa gtaatattta
     9781 ctcagctatt ccaagatttc tttaactctg tagcaatgga ttttatgaca tgggtaaaag
     9841 ttttatgtgt agcagcaagt gtaattgtgg ttaatgaagt tgtaaaatgt ataataagac
     9901 tggtaaaacc aaaaaagact gcttaaaaca aattttttag aagaaaacag actgactcaa
     9961 aatatgaatt ttgggtcagt tctgaataaa catttaaatt gggaggatag ttatgggtga
    10021 ctcaaaggta tttgaaaaaa tattctccag ccaatcagat agaggaaatt acactccttc
    10081 aaagggatat ctaagttatt ttatttcgta tattggttta gaagatgaag ttttgtacaa
    10141 tctcgagata tttaagacaa aacaaaatat tgatagcaaa aaagatattg ctttatttac
    10201 tgatgttata gcaaatccta gtgattttga tattataaat tattttaaaa gtggacttca
    10261 aaaatataga actagcatgg aagatgtaga tataaatatt ttgggatttg aagagattga
    10321 ttataaaata aagcaagcaa tggatagagt gttaaaagaa gaggaaaaag aatttactaa
    10381 tgatagagtt aaacaaaatt ttatagtgaa aataatggca tggataaaaa tttatatcgg
    10441 tgctttagat ataaataaaa atgaagctcc aaaagtaata ttttatggag atataaaaaa
    10501 acatgaagtt tatttactct taatattata cttggcaggt tttgatgttt tatatcttaa
    10561 tccaaattca aagagtaata tagatatttt aaaatcagaa agatacaata tagagtttga
    10621 agaagccaac ataatagaag aaaaaatttc ttttgaagaa agggttattt taggggaaaa
    10681 aatagataaa agttctgtaa aaaaagcttt tactgttggg gcagaagcat caaagcgtat
    10741 aagtgaggaa ttgttaaatg atgcaggatt tataaaacct tggcaactcc aagatagaaa
    10801 aataaaaaat ctacttctaa gttcaactgt tgatgaaata tcaatatact ggaatcaacc
    10861 acttaaatta agaccaggat ttaagtttaa tgatgctatt gtagaagctc caaattttct
    10921 ttctaagatt aatggaatat ataatgataa gaatgaatat attaagtttt tagatttatt
    10981 aagagattcg gaaagttcaa catttattga atttaatgga gatgtagata gattttcaaa
    11041 agcttttacg agagaagctt ttagtttatc ctttttattg gattcaaaag gtgtaataga
    11101 taaaaactct gttttaaata ataaagatta ttccatatca acactagcac ttaatcaaca
    11161 aattatgatt ttagagaaag tggaagagtt gttagaagga agtatgtttt tgaatggttt
    11221 aagtggagaa gacaagataa aaggtctatt tacagtactt cacatggata agaaatttgt
    11281 tcatatgatg aacaatttcg attactcact tataaaccca aaattgatta tatacatgta
    11341 caagagtatt gtatttgata aagaaatagt ttttcttatg cttttactta gtaagattgg
    11401 atttgatatt atcatattat gtccaggagg agaaaacaat atagagaatg ttataaataa
    11461 ccaattgatt gatatacaca gattggataa aatggtatat gaccttaaat taaattcgct
    11521 tgaaaatgat atacctttac ttaaaaaaat ttttggaaag aggagacgat tttagatggg
    11581 gataaatata aatagttttt caaaagataa gaactctgta gaggttactg agaatttgcc
    11641 tacagcagtt caagaagaaa acttcgatat aatggaatat acaaataata aaaaaaatga
    11701 actgagaaag tctaaggaag ttgaggcatt gacatccctt atagaagtag aaaatccaga
    11761 tacgatttta cagtttggta ggaaagcatc tgaaggagta gcaagagttt ctgatagcct
    11821 tttaaataca ataaaattaa atagaaatga agaaaattct aaaatgctgg ttcatttaac
    11881 taaaataatg gataagtttg atttagacga ttttcaagaa actaaggaac caaatttcgt
    11941 tcaaaaactt ttcaaaaaag ctaataatgc cattgaaatg atgtttcaaa agtatgaaac
    12001 attgggagga gaagttgaga aaattcaaat tgagcttgag caatacgaaa gagatatagc
    12061 actttctaat aagcaaatag gtgctatgtt aaatgaaaac tttgagtttt ataatgaact
    12121 tcaaaaatat attgttgctg gagaaatggc aatagaagaa atggataatg aaatactacc
    12181 tttctttaaa caaaaatcag agactagtgg agaccaaatg gatgttgtca attatcaaga
    12241 actattaaaa gtttatgata tgttaaatca aagagtctat gatttaagaa tagcagaaaa
    12301 tatagctatc caaacaatac ctatgcttag aggtatgcaa cataataatt atggtttaat
    12361 tagaaaaata aatagtgcat ttgtcgtaac tttaccagta tttaaacaat gtttatctca
    12421 agctatatta cttaaaaagc aagaattaca agcaaaatct ctaaaagcac ttgatgacaa
    12481 aactaatgaa ttattgctta gaaatgcaca aaatgtaagt actcaaagtg cacaaatagc
    12541 tagaatggct ggaacaagtt ctgttcaaat agaaacattg gaaaaaatgt acaatactat
    12601 caagtctggt atagatgaaa ctatgagaat agaagaaaac aatagagctt taattaagga
    12661 taatacaaag agattggaag aattaaatac gactataatt tataataagt agtattatat
    12721 taagggctaa tttgtataaa gttggccctt tctatgtata tgaggaggct agacattgaa
    12781 atatttcgat tatatctgca aagatgattt ggagagaatt tttttgaagg agccagaaga
    12841 ctttagtgct aagactgaaa aagatgtgtt gaaatatgca ctgggcgctt ttttatacgt
    12901 tccagctact caatataata tgatttataa gagtattata ggggatgtta agggagttag
    12961 accattagct atttgtttag aagatgctgt tggagtaaat ggagagttag aggctataga
    13021 aaatcttaga ttaattttaa aaaatattag caatgaaagt ataactaata aagatggaat
    13081 accactaatt tttgtaagaa taaaagatgt ggagcaactg ttgagaatta aagagattat
    13141 aattaaaaat agtcattcta taacaggaat attaattcct aaagcaaatt cggagttgat
    13201 tgaaaattgt atagaagctt tatattctat gaatcttcaa gatatgtatg ttattccaat
    13261 aatagagaca agagaattta tatataatga aaaaaaagaa cttagtttta ctaatttgta
    13321 caatgctatt ttaagacata agtcaagaat attaagcatt agagtaggca taactgatat
    13381 attagggatg tatggtataa ggagagataa aaacttctct atatataata atttgatttg
    13441 ttcttcattt atattagata taatcacata tcttcaaaga ccagagttag atatacctat
    13501 aagtggtgga gtatcagaat tttttgatat gacaaataag gatataagaa ataagtatat
    13561 agaagaaata ttattggata aatatcatgg attaattgga aagaccgtaa ttcatccaat
    13621 gcaaattcaa attgtacaag cgctatctac agtatcatat gaagatttta ctgatgcttt
    13681 ggatatactg gatagtacag acagtaagta tggtgtgagc aagggtgtat taggagagag
    13741 aatgaatgaa acaaatccac attttttatg ggctaaaaaa acattgattc tatctaaaat
    13801 atatggtgta ttaaataaag gagtagacta tgaagaattg cttaaatttt aattgtgaga
    13861 ttgacattat tgataatcca ttgaatttag aactaaatga ttttttagac gtaggagtaa
    13921 gaaataatag caaaagacgt tttttgttta tctcaaagaa actcggtaaa catttagcat
    13981 gtaagccaag tgagatggat aatttgggaa aattaatggc tacaatttat aatgaaaaaa
    14041 ataaggaaga atcaaatggt actgttatag cttttgctga aactggtaca gctgttgggc
    14101 atagtttttt tgattactta tgtggagatt atgaatttat tcatactact agagagcagt
    14161 ttgacgagtt agaaaatctg gaatttttag aggaacattc ccatgcaaca gaccagaatt
    14221 tatactttgg tatgcttaac aactttaaat ttggagatga gataatattg gttgatgatg
    14281 agattaccac agccaataca tgcatgaata taattaggaa aattcaaagc atttatccta
    14341 aaaagaaata cactatatgc tcaatactca attgggtaag tgatgaaaat ttaagtaaag
    14401 ttactcgttt agaaagagag ctaaattgta agatagattt tgtatactta tttaaaggaa
    14461 actttaaatt ttatatagat gaagatatta tttcaaatta caacgataat tatagtatta
    14521 ctaaattaga gactatttca agtgataaag taaatttagt agtaaatcat atttatgttg
    14581 atttagaaga ttatattgga aataagaaat atgtaaaata tacaggaaga tttggaatta
    14641 atagaagaga acaatttaga ttaaaagaaa tcgttaagag agaaagtaaa aaaataacta
    14701 tggccagtaa agaatcttta aaaaatgaaa aagaaaagat tctattttta ggtactgaag
    14761 aatttatgta tatacctatg ctgtttgcaa aagaaaaaga aaatcaatat gatatatact
    14821 atcattcaac aacaagaagt ccaattatta atattgataa gaagcattat cctattaaaa
    14881 gtaaatttat gctaaagagt ttttataata tagatattca aaattatatt tacaatatag
    14941 ataaacataa tttttctaag tgttatttat ttgtagagct gaataaaagt gaaaattctt
    15001 atctagaatt tattgatata attaaaaaaa caagtataaa agaattaact atagtatgtt
    15061 gtagctaaag tgttttaaca ggataaaata tatcacgatt ttaagatagg agttgagtca
    15121 tatgagagat tttagcacgt attctaaaga tgatgttatt tttttattaa aagatatatc
    15181 aaatttaatt gaagaagaag gaaataaaga aagagaatta aaaatacaaa atggtagaca
    15241 ttattcagaa atgataccaa tagagtatga agttagtgaa gattatctga atttatatca
    15301 tgagaaacta agagaaaata aagataagct tgcattttct ataggagtta tgtgtgaaaa
    15361 aataattaaa aaaaatggaa atgatgtagt actagtttca cttgctagag caggaacacc
    15421 tattggtatt ttggcaaaaa gatatataag aagcaagtat aatgtaagtt tacctcacta
    15481 tacaatctct ataataagag ataagggaat agatatgaat gcaattgaat atatagtaaa
    15541 gaatcatccg agctcaaaaa ttcaattttt agatggatgg actggtaagg gaactatatc
    15601 aaaagaactt gaaaaagcat gtgatgaact taatgttaaa tttaaaaaac attttgactc
    15661 aacacttgct gtattagctg accctgctgg atattcagga ctttatggaa ttagagaaga
    15721 tttcttaata ccaagtgcat gtttaaattc aaccgtttct ggtttagtaa gtagaactgt
    15781 actaagagag gatttaattg gtaaaaatga ctttcatgga gctaagtttt atagacattt
    15841 aaaagataaa gatgaatcta tgaactatat cgaaactata gaagaatgtt ttaaaaatca
    15901 atttaagaat atatctgatg aagttgaaaa ctgggaaagt gacattataa caagagatgg
    15961 atactttgat gttttaaata taaaagaaaa gtataacata acagatatta actttatcaa
    16021 accaggtgta ggggaaacga caagggtttt acttagaaga gttccgtata agattcttgt
    16081 taaagactta aatgataaat ctttagacca tatattcata ttagctaagg agaaaaatgt
    16141 tgaagttgaa caaatggatt taaaagccta taaatgttgt ggaataataa aaaatatgaa
    16201 agatatttag gaaatatatt agacaggaga atattgaatg attgtttttt cagatttaga
    16261 caggagtatc atttactcca ataaattttt aaatgctgat agtaaatatg ctaatataga
    16321 aatttatagg gaaaaagaaa tatcttatat atctttagat actataaatt taataaagca
    16381 aatacaatat tatggtatgt ttatacctac aactactaga acagtggagc aatttaagcg
    16441 tatagaattt aataaatatg ggatttattt tccttggagt ataacttcaa atggaggagt
    16501 tatacttaaa gataatgaaa tattgaaatc atggagtgaa aaaatagata aactaaaacc
    16561 tgattatgag cccattgaaa gtatgattca taaatttaaa gactatttga atgtagatgg
    16621 aataactaat tttaaagttg cagaagatac atttttttat atagttgttg atttctcaag
    16681 atttaatttg gattcaatca aagaatatac aaatatattg gaatcaaaaa attggaagtt
    16741 ttatgtgagt ggcagaaaaa tatattttat accaaaagaa atttcaaaag aaaatgctat
    16801 aaaatacttg actaaagaat taggaataga atatttttat gcagttggag attctattat
    16861 ggactatggt atgcttaata tctcaaataa atcctatgta ttgaagcatg gtgatataaa
    16921 taaaaatgaa atagaaaatt catttatatc aagttctttc aaaggaatga gtggaactga
    16981 agagatatta tctaacattt tagacgagaa ctgcctactt aatatataat gactgatata
    17041 taaataataa actagaaaaa tctgaaataa attatagtaa agtttatcat actaatttat
    17101 ttcagatttt tatcaattta tatttaagta agaactcaat atgttaaaat gaaggtggag
    17161 tcattgccca gactgagata catacctcat catcataatt ttcatacaca tgtggtatag
    17221 tactgttaaa ataaaaacta tctccttcct ccaatagata ttccttattt ccaagtgtta
    17281 tcttcatttt accttttatt atatagccac attcttctcc ttcgtgtgtc acaaattcac
    17341 tgtttttttg tgtatgacca tctagcgtaa caagtataaa ttctattttt ttcccagata
    17401 aattaggaac aagaagttca taaaattttg tagaatcatt agttactatt ttttttcgat
    17461 tatttttctt tactactata tcagagtcct ctcttccaat ctcttcaaaa aaataaccta
    17521 tatttatatc aagagctttt gatattttcc acattgctac aatagatgga acaaccatat
    17581 tacgctcaat ttgacttatt aagcctgtac ttaaatctga attttttgct aaagtagaga
    17641 tacttatatt tttagatttt ctaagagatc taattttgct tccgacatct atattcatta
    17701 gatacaaacc ccctcagaca tgattataac atataattta taaagattaa taaaataaaa
    17761 aaaagtttta taatgcatgt attttttatg ttatattgaa ttttctgaaa agatgcatta
    17821 taatagtatt aatattcaat atattgaata ttgataatga tattttaatt taatgaaatg
    17881 gaggtaatta agatgaagag ttttgtaagt cctgataata tttgggtatt atgggcagtt
    17941 gtaactggat gggcagcatt tagtatttac ttggaacaaa agtacaattg ggcatcaaaa
    18001 gtgtcgggag caataatagc tcttgtagga gcaatgttat tatcaaatct aaatattata
    18061 ccagtagagt ctgttgtata tgaccaagta tggggatatg ttgttccttt agccatagct
    18121 ttattgttat atcaatgtaa tattaaaaag atatggaaag aaagtggaag attgctcatt
    18181 atatttcttg taggttctgt aggaactgta cttggagcta tgattggatt tttagcatta
    18241 aaaaatgtag taccagattt aaatattgtt gcagctatga tgacaggttc ttatataggt
    18301 ggaaatgtaa actttgctgc tatgtcaggg gcgtttgatg cgccaggaga attagtatca
    18361 gcaacagttg tagcagataa tcttttaatg gcattatatt tctttgtctt aatagctata
    18421 ccatcaattg gattttttag aaaacatttt aaacatccac atgtagatga aatggaaagt
    18481 ataggtataa ctgaaggaga aacagtagca gcaaattatt ggggaagaaa agaaatatct
    18541 ttaaaagata tagcaatagc cattggtagc gcctttataa ttgtcgcagt atctgtagaa
    18601 ctatcaactt ggtttaaagc tataatacca ttatcaaatc cttttttagc aatgttaaat
    18661 actttatttg gaaatcaata tctaataata actactttga ctatgttgtt tgccacattt
    18721 atgcctaatt tctttggtga tataaaagga gcacaggaat tgggtacatt tttaatatat
    18781 atattctttg ttgtagtagg tgttcctgct tcaataacat taataattca aaaatcacca
    18841 ttactacttt tatactgcgg aataatggta ctaataaaca tgctagttac atttatagtt
    18901 gcaaaaatat ttaagtttag tttagaagaa gctattcttg catctaatgc aaatattggt
    18961 ggtcctacaa cagcagcagc tatggcaata tcaaaaggat ggtctaagct agtagggcca
    19021 atacttatag ttggaacatt tggatacata gttggtaatt attttggtct tttagtagga
    19081 aatattttga tataatttta cgtgaaaaga agttgttttt tagaaagatt tttatttaat
    19141 tggaggttgt tatgattttc gatggacatt cagatacttg ggcagatgta acaataagaa
    19201 ggcttaacgg ggaaaaagat gtatttagaa gaatccatct tgataatttt aaaagagcaa
    19261 atatagaagg agctattttt gtaatatgga tagacccacc atatgataaa gagcctgaaa
    19321 aaagagttaa acaaattata agctctataa aagatgaaat tgaagatatg aaagatgttg
    19381 taaacatagt aaaaaaatat tcagatatag ataaaggtat aagtgaaaac aaaataaata
    19441 ttttaattgg tcttgaagga ttaagccata ttggaagaaa tatagattta ctagattatt
    19501 tttataaaga agttggtgca agacatgcat cattaacttg gaatgaacag aatgaacttg
    19561 ctacaggatg tttaggggat gaaaatcgtg gtttaactga aataggtaaa aaagcagtca
    19621 ataaaatgga aaaattgggc atgatagtag atgtgtcaca tttaaatgaa aaatcatttt
    19681 gggatttaat gtctgttgca agtaagccag ttatagcttc tcattctaat gctaggagtt
    19741 tatgtgatgc taaaagaaat cttacagata atcaattaaa agaaatttca aatacaggtg
    19801 gattagttgg aataaatagt tttagaggat ttactaatag taatcctaag aagcaagatt
    19861 taatacattt ggttgaccat atagactata tggtaaatct tataggtata gaacatgtat
    19921 cttttggttt tgattttagt gattacttag ggaaagagac tataggttct tttactggaa
    19981 atgctagtgt gccaagtgta gatggtcttg aaagcacaca tacagcacag aacatagtag
    20041 tagagcttga aaatagaggt tataaaaaga aagatataga gttaatctct agtggtaatt
    20101 tttataggct ctttaaagat atactaaaat aatataataa agaacttaaa tttataaaat
    20161 agtatattta tacaataata tctacatatt taaattggcg ttcataattt attaaattaa
    20221 attttaatgt tactagaagt ttcaattcta gtaacatttt ttatgttaaa aatagatata
    20281 gatatatatt gacaatgata attattattg ataaactata aaagtgaaaa tgataataat
    20341 tttcatttta attaataaaa gatttttaag gagggagaat gaagaaaagg tatttagtca
    20401 taggaataat aattttgtct tatttttctt tatttatagg agctgaagat ataaatataa
    20461 tgcatatatt tgcaaaaaat cagcataagc ttatgatatt tatcatgagt agggtaccaa
    20521 gattaataag tatattgatt gctggtgtag gaatgagcat agcaggtctt ataatgcaac
    20581 agataagtaa gaataaattt gtatcaccta caacaggtgc tacaatagat gcagctcaat
    20641 ttgggatagt aatatgtatg cttttagtac caactgcctc tatttttaca aagacaataa
    20701 tagcatttgt attttctctt gtagggactt ttacgtttat gaaaataata gggaagttac
    20761 aatttaaaaa tataatcttt gtaccattag taggtataat gtttggaaat ataataggtt
    20821 ctatgacgga ttttatcgcg tataaatacg atttgagtca aaatgttagt tcttggatgc
    20881 aaggtgactt ttctatgata cttaaaggaa attatgagat attatatatc acaatacccc
    20941 ttataatatt agcatatatt tatgcaaata aatttactgt tgttggtatg ggtatggatt
    21001 ttgcgacaaa cttaggtctt agttacaaaa gaattgtcaa tataggtctg ataatagtag
    21061 cacttgttac agtatgtgta gtcgttacag ctggtaatat cccttttata ggtctaatag
    21121 ttcccaatat cgtatccttg tatatgggtg ataatataag agcaagcata tggtatactg
    21181 gtttacttgg agcggtattt gtacttatat gtgatatttt tggaagaatt attatttatc
    21241 catatgaaat atctatagga cttacagttg gagttatagg aagtatacta ttcctttatt
    21301 taatattaag gaggaatgtg aatgaagctt agtctcaatc aaaaaattta ctttgtaagt
    21361 atattactat tcatatcaat agcacttttt ataatttatg gaatagacat gaatcattta
    21421 gaatatgcat tatcacaaag aataccaaaa atatttgcta tggtattagg tggaggatgt
    21481 atagcattta ctactgtagt gtttcaaaca attacaaaca atcaaatatt aacaccaagt
    21541 gtactaggtt tagattcatt gtatgtaatg attcaaacta taatagtatt catatttggt
    21601 tcaagcagta gtctgattat aaatgaaaat tataatttta ttattaatgt agctatgatg
    21661 attggagctt cattgttatt atataagatg ttatttgaaa aaaataaaaa taatattttc
    21721 tttttaatcc tagtaggtat gatatttgga accttattta aaagtgcaac aacatttatt
    21781 caagtaatga tagacccgaa tgaattttta gctttacaaa ctagtataat ggcaagttta
    21841 aacaatataa acactaatgt attgttaata gcatttataa taattattgc cataatacct
    21901 tttatatatg atgaaataaa gtatttagat gtattgtcgt taggtaaaga acaagcaatt
    21961 aatttaggtg tagattttga taaggcagtt aaaaaaatga taatattaat agcaatttta
    22021 gtctcaatat caacagcact tattggacct atgacatttt taggactttt acttgctaat
    22081 ataacaagag aaatttttaa aacatataag catacatact tgatttcggg ttctatgttg
    22141 atagggatga ttacattgat aataggtcaa ttttttatac aacatgtatt taagtttgat
    22201 acgactttaa gtgtagtaat aaattttata ggaggaattt actttattca attactatta
    22261 aagggggcaa atagatgata gagataaaaa atatatttaa aagatataag aataaaaatg
    22321 ttgtagatga tgtctctttt agtatagaaa agggaaagat aacatctttt ataggaccaa
    22381 atggagctgg aaaaagtaca gtactatcaa tagttacaag gcttatagga ggtgatggcg
    22441 gagaagtaat aatagaagga aaaagcttga ctaattatag caataaagaa ttagcaaaaa
    22501 aaatagctat tcttaaacaa tctaacaata taactttaaa gcttacaata agagaattag
    22561 ttggatttgg aagatttcca tatagtgaag gtaatctaac taaagaggat gaaaattata
    22621 ttgatgaagc aatagaatat atgaagttga ctgatataca acataagtat ttagatgaat
    22681 tgagtggagg tcaaagacaa agagcttata tagcaatggt aatagctcaa gatacagagt
    22741 acatattact tgatgaacca ctgaacaatt tggatatgaa ccattccgta cagatgatga
    22801 aggtacttag aagtctttgt gatgagttag ataagactat agtattagta atgcatgata
    22861 taaattttgc atcatgttat tcagataata tagttgcatt aaaaaatgga aaagttgaaa
    22921 aagtaggtcg tacagatgag atagtaaatg aaaaagtttt agaagatatt tatgagatga
    22981 attttaacat taagaatata aatggaaatc gaatctgtat ttatttttaa aatattgtat
    23041 atgaaaataa gcttgctata tgatttttta taaagttttt aaattaaaat aaagattaat
    23101 aggagagagg aaaatattga tatgaataaa aaagcagcaa tagtagcagc agtagctatt
    23161 ataggattag tgacagtgtt tgcattaggt ggaagtaaaa agaatgaatc aaaaacatca
    23221 gaaaattcaa ataataccat aaagataact cataacttgg gagaaacaga tgtaaaatta
    23281 aatcctaaaa aagtagtagt atttgattat tcggctttag atacaatgga tgcattaggt
    23341 gtagctgaga atttagtagg acttccaaaa acgagtttac cagcatcttt agaaaaatat
    23401 aaggataaga agtatgcaga tttaggaggt ttaaaagaac cagatttaga aggtataaag
    23461 tcggcaaatc cagatttaat tataataaat ggaagacaag aagattttta tgaacaattg
    23521 tcaaaaatag caccaacaat aagtacaagt aaagatgata agaagtactt agaatctgtt
    23581 aaaaataata tagacaaaat agcaaaaata tttggagtag aagaaaaagc aaatcaagaa
    23641 tttagtaaaa ttgaaaagaa aatagaaact ttgaataaaa aagtaacaga taaaaattta
    23701 aatgctttaa ctataatggt aaatgaaggt aatttaagtg tatttggtga agaatcaaga
    23761 tttagtatat tatacaatag ttttggattt gaaaataaag ataaaaatat aaaagaatca
    23821 agtcatggac aaaatattac ttttgaatat atagctaaac aaaatccaga agttatgttc
    23881 gttatagata gaggaatagc tactggtagt gatgtaaaag aaagctcaac tgcaaaatct
    23941 gttttgaaca atgatataat aaaatctatg gatgcatata agaatgataa tataatatat
    24001 ttagattcac caacatggta tgtaaatgat ggtggtctaa catctttaaa taaaatgata
    24061 gatgatgctt caaaagcggt aaattaataa tccgatataa tcaaaatgta ttttttgtaa
    24121 aatgattatc aaataaacta ggagttttta agaactccta gtttattttt tgcataataa
    24181 agatatagtt taaacaataa tattatttat aataagataa atctattcaa aatctaataa
    24241 aatatgaagt tatactagac aaaaagaata actcttaaat ataattaagt tatataataa
    24301 tatataatta taatgatata attttaatag gaggtttgta attaaaaagt atataaatta
    24361 tattaatagt aataatctat aagaacttat atattagaaa aaaatttttg tatatataaa
    24421 ggactctaaa gatgaactat ataaaacaag gtttatatat tctaatagta tagaaaattt
    24481 tattgtaaac gcatgtatat tattagaaaa aatagtttga aggtattcaa taaacataaa
    24541 aaacaatata ggggataaag gtgttttatg aagagatttt tgaggagaat tatcttagtt
    24601 ttatttattt tgttgatttt tataagtttt atttctatta aattaattca taatgttgga
    24661 gattatggaa aattgattaa ttatgttggg attgtttgtg gagctagcca acgtctaact
    24721 aaactagaga tgaatcatca accaaatgat gaattaatag aatatattga tgaaatccta
    24781 caggagttga ttacagggca tggagattat ggtttagtaa tcactgattg taatgaatac
    24841 aatgaggact tacttttatt agaaaaaaag tgggaagatt taaatattga aattaaaaaa
    24901 gtaagaatga aagaacagaa taaccagtta ttaagtataa gtgaagagtt tttttctctt
    24961 gcaaatgata cagtgtttaa aatagaaaac ttttctaaag aaaaaagtaa ttacttaatg
    25021 actttaataa taattatatc tattataggt atattagcat gtatcatatt gattttacaa
    25081 tatagtaaaa aaatggttag actggaaaaa ttaaatgtag atttaaaaaa tattgcatat
    25141 aaagatgaac taacaggagt aaatactata gaaaaattta aattggatgc aaatcaaaat
    25201 atttgtataa ataaggataa gaaatttgct gtattctata ttgattttga aaactttaaa
    25261 tacattaatg atatatttgg atatgattat ggtgacatga tactgaaaag atatgctaat
    25321 cttatgatga atgacatagg gaaatatgaa atatttgcaa gagaaattgc agatagattt
    25381 gttgcgttaa gatgctatgt agataaggaa gatttagtag taagacaacg agatgtagac
    25441 aatgaactaa ttaatataac aaatgaaatt aaaaataaac atagtattac tgttgtcagt
    25501 ggaatttgtt gcattgaaga tgtaaatgaa aaattaagta tagatggttt aataaataga
    25561 gcaaattttg cacaaaaaac tgttaagaat aaaccaggta ctaattatgc tttttataat
    25621 gacagtattc gtaaaaaaat gattgaagaa aatactatca agagtagaat acatgaagct
    25681 attgaaaaaa gagaatttat agtttattta cagcctaaag ttaatttaca tagtcaaaaa
    25741 ataaattgtg cagaagcttt agttcgttgg cttactccgg ataaaggtat tatatctcca
    25801 gcaatattta ttccagtact tgagaagaat ttttttattg ccttagtaga taagtatgtt
    25861 tttgaggagg tttgtaaatg gattagaaag aggttagatg aaaataaacc ttttgttcag
    25921 atatcagtta atgtttcaag aatacaattt tataacacta aatttgtaga aacttattcc
    25981 aatatacaaa ataaatacag gatacctaaa aatactatag aaattgaatt tacagagagt
    26041 gttgcttttg agaatcaaaa acatcttttg gaaattatac atgatttgca tgaaaatgga
    26101 tttacttgtt ctttagatga ttttggaaaa ggttattcgt ctttaagtgt tttaaaagat
    26161 ttaccatttg atgttttaaa gcttgactct atgtttttca aggctagttt agataaagat
    26221 aaagagaaaa tagtaataaa aaatattgta catatgttaa aagagcttaa tatcacaact
    26281 gttgctgagg gcattgaatg caaggaacaa gttgaatttc ttagggatat tgggtgtgat
    26341 ttagttcagg gatttgtatt ttataaacca atgccaatat tagaatttga agaaatattg
    26401 gataaagagt ttgtttataa tagctaaaat gtactttata aaatatgaac taattaagta
    26461 aaattatttt gtactgaata aatttttact ttatttacag aatagtgatt atttacagaa
    26521 aagggcgaaa agtgtattcc tttaagtatg ggatggatag cacaaatagg ggagaaaaaa
    26581 tattggccat ataagaatgc ataataatat aaatatttga aaggtcagca ttatataaaa
    26641 attaaaaaga aaataaataa tttttctata aaaaagagac tatgagaaaa gttactcata
    26701 gtctcctaaa taatgtattt attttcttcc tgcaacccat tttaagcccc aatgaaattc
    26761 agtatccatt tctctatgac ctttgaagta tttaactact ttttcaacac tgaatgtctc
    26821 atcatttaca ttttctatca atgctattga acacatatta tagccatttt tatgttcatc
    26881 aagtttgaca actaagtctg aatcttgttt ttgtttgatt gttacaattc catcagcttc
    26941 agaccagtta gctacacctt cgtatataaa agcataaata agtattcttt ttatatcttt
    27001 tattttatta ccatttattc ttaaattttc tccttgtgta ttacttcctg ttctgtcatc
    27061 tccatctaat tgagcaaaag gtggattgtc taaactacca aaagcatttc ctaatgcttg
    27121 aacagcacct tttacaccat ttttcatctc aaataggcaa cccaaatcta aatctatatt
    27181 actgcttctt aaagagccaa aaaaaccctt tttttgtact ttttgattcc aatttaaatt
    27241 aactaagatt tcacctaaat cgctattttc cttttttgta aggtttattt tttgtccctt
    27301 ttttaattct atagccatag taatcttcct ccacaaacat agatttattt aaatggtagc
    27361 acttaataag tcaatattca acaagattag aataataata ttaaaactat actaaatata
    27421 ctaaaaagta ggaatcacaa tacctttgta tttttcttca attaagcttc ttgctttatc
    27481 tgatgtaaga acatcttgta gaactttaat cttttcactg tctttatctt cagttctaaa
    27541 tgctaaaaga tttgcatact cgtcatttat aggagctgta taaattccgt ttttcttggc
    27601 atcaagacca gcaggtacag cataagtagt atctataaat gcagcagtaa catctggaag
    27661 agaagatgga atttgagcaa tatctaactc tttgaattgt attccctttg gattttctat
    27721 tatgtcctta ggactaacta atccatcccc tttaggtaac gttaaaagtc caatactttc
    27781 aaggtatcta aggttcttag agcaagaaga tgggttattg cttattgcaa ttgtatctcc
    27841 ttttttaaat tcatcaacag attttatctt ataagagtaa agtattgctg ggcatacata
    27901 tagtttttta ccagccatta ttttgtaacc tttggcctta acagcttctt ttagataagg
    27961 ttcatgttga aatagatttg catcaatttc accattattt aaagcttcgt ttggaagtat
    28021 gtaatcatca aagtttttaa cttctaaagt atatcctttt tctttaataa gtggttttaa
    28081 ttcttctaat aactctcctc ctggaactaa agtagcacca acaacaattt ttttatcatc
    28141 tttagcttta gaacatccaa ccacagctaa agttagtact agacataata acaaacataa
    28201 taattttttg aatttcatat aaattccctc ctgaatataa ttgattagtt aaaaataaaa
    28261 taccattctt tatcacactg caaaataaaa ataagcctga gtttaaactc aggctttaaa
    28321 agctaattta gactcatctt tcagtataat actgcaggat ttagcaccaa tgtatataaa
    28381 aatatactgg ttgctgggtt tcatagggcc agtcccttca ccactctgga taagaagtat
    28441 caatttttaa ttatgttata aatattatca tgatttttta cgtctgtaaa cataatttta
    28501 taaatatttt aaaatcttta atgtatttta tttaacacct aaaattccag aaactagaat
    28561 atcagtatca gcacctaaga aatagtcatt tatttcaata gaatccagag tatttctcaa
    28621 agcattttct tcatgcctta taccaataag tttattttct acaaatgcaa catcacattt
    28681 tccaaaaaaa tctccaaaaa attttatact agttattatg cctttatcaa catttaaatt
    28741 aaactcaaca tttccaccag aatattttaa ttcatttgaa agagtatatt ttggtgaatt
    28801 accaaaattc caatcccaag tttcgtattt tgatttagta agcttttcta tttgttttat
    28861 atcatgctca ttcaaacaat aattagtatt atcagtattt gttttagaaa gataatccat
    28921 tatagcatct ttaaattcta atatgtccat ttttgaatgt aaatgttcac ttatattggt
    28981 tacacgagat tttacagatt ttattccttt tccttcaaat tttataggtt taacctttaa
    29041 tgcttttgag aggtcattta tttcagatga aaataaaaga gtaccatgat gcattacttt
    29101 gtttttgtag ttgtattgag catttccaga aaatttcttg ccatctataa gaaggtcatt
    29161 tcttccagaa aattcggcat tgacatctag tgttttaagt aaatctatta tgggctgagt
    29221 gaatcttctg aaatcactaa aattattatt gttacaagct ataaatgtaa aatttatatt
    29281 tcccaaatca tgaaatacag ctccaccacc agactgtctc ctaacgacag gtatagaata
    29341 ttcttttata tattctaaat ttatttcaga aagtgtgttt tggttttttc caacaattat
    29401 agaaggttca ttcctccata aaataaataa gtcttcatca aaatttttta gaagatattc
    29461 ttccattgct aaattaaaat aagggtttgt tttttcatta taaattaata acattaaagt
    29521 agttcctcca tagaattgat aaaattttta ttatgaatac aattaatttt ataattcgac
    29581 aataatataa aaactccttt aaattagaaa ttttaaaaac taccttgcaa agtttaaata
    29641 aataatatat actcaaaata tgtttaataa aagtgaatag aagggtagag gcgcaataat
    29701 ctatcagtac taataaggag ttaagcacag agagttatta ggaaaggaga tattgccgaa
    29761 gttttataat cgatgcttta agattatatt gctgggggta catagaaaat atgtacaact
    29821 gtcacaggtt tatttgtggt gagctatcat ttaaggaatt atattatatt tatttttact
    29881 attgttgata tattgtaatg tttaagcctt gagtgtttac cactcaaggc ttttttagtt
    29941 ttattgtaac ataataccct gtacagttca caaaattaaa aggagaggga gatttatatg
    30001 aggaacaaaa aaattaatat tatttttctg acgacaatca tgttcataat gtcaacagta
    30061 atggtttttg cagaagaaga tatagacact attgcactag ctaatgcaga aaaatttggg
    30121 attttaactt taataccacc attagttgct ataatacttg catttataac taaaaacgta
    30181 ataatttctt tacttatagg tattctttct ggtagtttta taattaaagc tagtggtatt
    30241 aatgtttttg cgacatttat acaggcattt ttagatttag tagatagagc tttagtatct
    30301 ttagcagacc cttggaatgc agggataata ctacaggttt tggcaattgg aggagtaata
    30361 aatcttgttg ctaaaatggg aggagctaaa gctatagctg aagcacttgc taaaagagca
    30421 aagtcagcaa aagggacaca gcttataaca tggtttttgg ggcttttagt attctttgat
    30481 gattatgcca attcactaat agtaggtcct atgatgagac ctgttgcaga taaaatgaaa
    30541 atatcaagag aaaagctagc atttataata gatgccacag cagcaccagt tgctggttta
    30601 gctataatat ctacatggat aggtcttgag gttggtttaa tacatgatgc ttttgaaagt
    30661 ataagtatag atgtagatgc atttggtata tttttaaata caataccatt tagattttac
    30721 aatatattaa tattagcttt cattgtaata tcagcattat tattaaaaga atttggtcca
    30781 atgagaaaag ctgagataaa atctagaagt agaaaaatta gtatagacct tgatgaaggc
    30841 gtagaagagt tggatgattt agctccaaaa aatggagtaa aattgagtgt atggaatgct
    30901 ataatcccaa taggaacatt gataatagtt gcattagcat cattttatta tagtggatat
    30961 acatctataa tgggaggaga cgataaggct ctgatacaac tatttacaaa ttctccatat
    31021 tcttttgaag caataaaaga agcatttagt gcatctgatg catctagagc attatttcag
    31081 tctgcacttg ttgcaagttt agttgctatt ataatggctg tagtaaaaaa gatttttaca
    31141 atatcagaag caattgatgt ttggatagat ggaatgaaaa gtttagtaat cactggtgta
    31201 atattaatac ttgcatggtc attaagttca gtaataaaag agttaggtac agctaagttt
    31261 ttaatacacc tattatcagg ttcactacca ccattcttat taccaagttt aatatttggt
    31321 ttaggagcaa taatatcttt tgctactgga acagcttatg gaacaatggg tatacttatg
    31381 ccacttgcaa ttccattagc atactcatta aatcctgata tgtcttatgt aatagtaagt
    31441 actagtgcag ttttaacagg tgcaatattt ggagaccatt gttctccaat ttcagataca
    31501 acaatacttt cttcaatggg agctggctgt aatcatatag accatgttaa cactcaaatg
    31561 ccatatgcta tatttacagc agtaatcact attgtatttg ggtatatacc agctggactt
    31621 ggattgccaa tatatatagt attaccagtg gcaatagctg ctatatttgt aggtattcaa
    31681 ataattggta agaaagttga tgaagcggaa atagaacttg tagaataaag atataaataa
    31741 gtttcacctt ttattatcac tattttgtta gtttttagat aattttaaaa agttattgaa
    31801 aataatggcg aaatatagta aaataaaaga gtgata
//
LOCUS       DAEQJM010000046        28981 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.046, whole genome shotgun sequence.
ACCESSION   DAEQJM010000046 DAEQJM010000000
VERSION     DAEQJM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28981
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.046"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            186..1610
                     /locus_tag="KRQ43_002496"
     CDS             186..1610
                     /locus_tag="KRQ43_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBH2742846.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDALFKRLESK"
     gene            1645..3774
                     /locus_tag="KRQ43_002497"
     CDS             1645..3774
                     /locus_tag="KRQ43_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH2742847.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKNFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMTLEVKDIVFNFYTNRLKAFIDK"
     gene            3804..4226
                     /locus_tag="KRQ43_002498"
     CDS             3804..4226
                     /locus_tag="KRQ43_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2742848.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            4245..5396
                     /locus_tag="KRQ43_002499"
     CDS             4245..5396
                     /locus_tag="KRQ43_002499"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH2742849.1"
                     /translation="MKKAIQFGAGNIGRGFIGSLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEEILNNIEKSYIFMKNL"
     regulatory      5502..5603
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            5786..6358
                     /locus_tag="KRQ43_002500"
     CDS             5786..6358
                     /locus_tag="KRQ43_002500"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBH2742850.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            6422..7072
                     /gene="fsa"
                     /locus_tag="KRQ43_002501"
     CDS             6422..7072
                     /gene="fsa"
                     /locus_tag="KRQ43_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH2742851.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGAFLKL"
     gene            7224..10148
                     /locus_tag="KRQ43_002502"
     CDS             7224..10148
                     /locus_tag="KRQ43_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2742852.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYGTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
     gene            10737..11195
                     /locus_tag="KRQ43_002503"
     CDS             10737..11195
                     /locus_tag="KRQ43_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH2742853.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFILGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLRTLKSL"
     gene            11256..11531
                     /locus_tag="KRQ43_002504"
     CDS             11256..11531
                     /locus_tag="KRQ43_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH2742854.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            11590..12864
                     /locus_tag="KRQ43_002505"
     CDS             11590..12864
                     /locus_tag="KRQ43_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH2742855.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            12994..14046
                     /locus_tag="KRQ43_002506"
     CDS             12994..14046
                     /locus_tag="KRQ43_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH2742856.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMDFEDAAMIEPLAVAMHGVLNIGVQVGD
                     AVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDIDPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            14046..15077
                     /locus_tag="KRQ43_002507"
     CDS             14046..15077
                     /locus_tag="KRQ43_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBH2742857.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKDIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMASGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            15169..15981
                     /locus_tag="KRQ43_002508"
     CDS             15169..15981
                     /locus_tag="KRQ43_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH2742858.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            15984..16904
                     /locus_tag="KRQ43_002509"
     CDS             15984..16904
                     /locus_tag="KRQ43_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH2742859.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            17079..17525
                     /gene="rpiB"
                     /locus_tag="KRQ43_002510"
     CDS             17079..17525
                     /gene="rpiB"
                     /locus_tag="KRQ43_002510"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH2742860.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            17564..18229
                     /locus_tag="KRQ43_002511"
     CDS             17564..18229
                     /locus_tag="KRQ43_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH2742861.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            18339..19841
                     /locus_tag="KRQ43_002512"
     CDS             18339..19841
                     /locus_tag="KRQ43_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBH2742862.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTNIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNNSNLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(20153..21745)
                     /locus_tag="KRQ43_002513"
     CDS             complement(20153..21745)
                     /locus_tag="KRQ43_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH2742863.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSYN
                     INCYYKEFALPYFYFFGTPVHLSKVELEFVCIGIILSSFLLTILCFTLYKKNKQTKVK
                     FLENVISLFSKVKIELTLILTLILLTLRFHAFTSNKMFYNTNLIIYNFIIISIVYIIY
                     ENIKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFF
                     MYIYYSEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEV
                     IGDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDM
                     LKNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQ
                     SIVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYID
                     MFIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELEN
                     AHMEIIIDADLFKVMLTFRRVN"
     gene            complement(21714..22430)
                     /locus_tag="KRQ43_002514"
     CDS             complement(21714..22430)
                     /locus_tag="KRQ43_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742864.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSREIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(22971..23771)
                     /locus_tag="KRQ43_002515"
     CDS             complement(22971..23771)
                     /locus_tag="KRQ43_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH2742865.1"
                     /translation="MTFKNKKFTINKYEILSIILVLCLILTGFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNVGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(24086..24817)
                     /locus_tag="KRQ43_002516"
     CDS             complement(24086..24817)
                     /locus_tag="KRQ43_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742866.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(24804..25499)
                     /locus_tag="KRQ43_002517"
     CDS             complement(24804..25499)
                     /locus_tag="KRQ43_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2742867.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(25501..26292)
                     /locus_tag="KRQ43_002518"
     CDS             complement(25501..26292)
                     /locus_tag="KRQ43_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742868.1"
                     /translation="MKNKFFTTLLTGFFAIVFFFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            complement(26302..27114)
                     /gene="modA"
                     /locus_tag="KRQ43_002519"
     CDS             complement(26302..27114)
                     /gene="modA"
                     /locus_tag="KRQ43_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH2742869.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(27749..27949)
                     /locus_tag="KRQ43_002520"
     CDS             complement(27749..27949)
                     /locus_tag="KRQ43_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH2742870.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(28174..28350)
                     /locus_tag="KRQ43_002521"
     CDS             complement(28174..28350)
                     /locus_tag="KRQ43_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742871.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(28404..28493)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            28678..>28981
                     /locus_tag="KRQ43_002522"
     CDS             28678..>28981
                     /locus_tag="KRQ43_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2742872.1"
                     /translation="MSKTKVSSEQKIEAIESYLKGENSVIKIMEELNIGKRTFREWMR
                     NYETFGNDGLIKQSHKSCYSKEFKLNAIESYLNGEGSYDTISKKYKMRSVNPLKAWV"
BASE COUNT        11366 a         3305 c         4849 g         9461 t
ORIGIN      
        1 aatcatatac tccaaaatac tacataaata aaattaaaca aaaactaaaa tgacaaatgt
       61 cattatctaa agtgacatag aaacggtttc ttaaagttgt tactataaaa tataaactct
      121 ataataaaag tataacaaaa gggaatcata tcgatataga atataattca agaggaggta
      181 aaattatgag tagttctaat caatcgacaa taaagacatc tatacagcga gtagggaaat
      241 ttttaagtgg tatggtaatg ccaaatatag gagcttttat agcatggggt cttataacag
      301 cattatttat accaacagga tggatgccta atgaaaaatt gagtactata ggcgacccaa
      361 tgataaaata ccttttacca ctattgatag cttatactgg tggtaaagca atagcaggac
      421 aaagaggtgg cgtaataggt gcagcagcag ctatgggagt aattgttggt gcagatatac
      481 caatgtttat cggagcaatg ataatgggac catttgcagg atgggtaatt aagaagtttg
      541 ataaatttgt agatggaaag ataccaacag gatttgaaat gttagtaaat aacttttcaa
      601 taggtataat aggtatgctt cttgcaatac taggatttta tgcaattgga ccagcaatag
      661 tagcagggac agctcttata gaatctggag ttcaatttat agttagcaaa agtttattgc
      721 ctctagtttc agtatttata gaacctggaa aagtattatt cttaaacaat gcaataaatc
      781 atggtatatt agggcctata ggtatagctg aggcaaaaga agcaggtaaa tctataatgt
      841 tcttactaga aagtaaccct ggaccaggtt taggagttct attagcatat tggatgttta
      901 gtagaggaag tgtaaaacaa tcagcaccag gagctgtaat aatacatttc tttggtggta
      961 tccatgaaat ttacttccca tatattttaa tgaatccagt tttaatattg gctacaatgg
     1021 caggtggagc agcaggaata ttgacttttt caatattagg agctgggctt gtagcagcac
     1081 catcaccagg aagtatattt gcacttatgg cactagctcc aaagggagga ttacttccag
     1141 tattagcagg agttgcagtg gcaacagttg tatcattctt agtggcagca ccatttgtta
     1201 agagagcttc agcaaatcaa agtgaagaag acagtacttc tttagaagaa gctaaagcaa
     1261 aaatgagtga tatgaaatct gcaagtaaga actctgagaa aaatattgag gaaaaacagc
     1321 ttgaagtaaa tgagattaag aagattgtat ttgcatgtga tgcaggaatg ggttcgagtg
     1381 caatgggagc ttccagattt aaaaatagaa taaaaaactt agacttaaat atagaaatta
     1441 caaattcatc tgttgataat cttccagatg atacacaaat agtagtaact cacaatacat
     1501 tagttgaaag agttgctaag aataattcaa gtgttgagat agtttcaata aacaattttt
     1561 taaatgaccc aaatttagat gcattattta aaagattaga atctaaataa aaataaaaag
     1621 taccactaat taggagtgga taatttgaaa aaaaagaaga ttacatctag gcaaaaaaag
     1681 ataatactaa tgatagtaga aaattcaaag aaaaacattc caataactat ttctgagatt
     1741 gcagggactt tagagctaag ttcaagaact gtacttagag atatgtctgg aattgaaaaa
     1801 tggtttgatg aaaatgattt taactttgta aaaaaaccag gagtgggatt gattttagag
     1861 gaaaatatag aaaatcaaaa ctttataatt gagttgttag aagaagaaaa aatagaaaaa
     1921 gaatacagca aggaagaaag aaatttaatt atattatcaa agctactagt ttctaacgag
     1981 ccagtaaaat cctattattt tgcaaaaata ttaaaggtat ctgaaggggt actgaataat
     2041 gattttgcct tagcaagtaa atggttggaa agatttgata ttgagcttgt tagaaaacca
     2101 gggcttggtg tctacttaaa aggtcaagaa aaaaacttta gagaggcata tgtaaatctt
     2161 atatacgatt cattcaatga aaaagaaata ctagatatgg tcagaaatat aagtgaaaat
     2221 atacaaacag ataaagcaat agaaatttta agtgaaaata gacttttaaa tttaatggac
     2281 aggtgcataa taagaaaagt tgaagctaca ttaacaaaga agctttcaga tttagatgta
     2341 aatttagctg atagtgcata tatagggctt gtagttcata tttcattagc cttacagagg
     2401 ataaaaaatg gtgaaaatat aactatggat aaagagtttc taaaagaatt atctataaca
     2461 gaagagttta aattagctaa agaaatcgta aaaggtatgg aaacagattt taacatggat
     2521 ataccagtag atgaggttgg atatataact atgcatataa gaggtgcaaa gcaaaggtca
     2581 tcttcaaacc ataaggcttt aaacttagat gatatagaaa taatggaaat tacaaataag
     2641 atgatagatt tggcggaaga tgaatttaaa ataagtttaa aaaatgacga gaggttattt
     2701 aaagacctag caaatcactt agggccttct ataaatagat tgaatatggg attagaaata
     2761 agaaatcctc ttttagatga aataaaaagc aagtattcat atgcctatga tggagttgaa
     2821 aagatttcta gaattataaa agataaacta aatataaatt caatacctga atcagaaata
     2881 ggatatattg caatgcactt tgcatcagcc atagaaaaaa atcttatgat gaatactaat
     2941 ataaatattg ttgtggcatg tcccactgga ataggtactt caagattctt atcaactaag
     3001 attgaaaata aatttcctaa tttaaatata cttgaaacca tatcagctat aaacatagat
     3061 gaagagtatt taaaagaaaa agatgttgat ttaatagtgt ctacagttga gttaaataca
     3121 agtttaaatt atatatgtgt aggtccattt atgagtttag atgatgaaca gataatcaag
     3181 gaaaaaataa aatctatagc tcaaaataaa ttaatcaatt taaatgcgaa aaatgatact
     3241 aaaagtaaga ataaagtata tgaacagata acagaaagta tgaatatagg aaaagatatt
     3301 cttcaatttt tagaggaaat tagatttgaa aaatttgaaa gtaaagattt aagtgagctt
     3361 attgaagact catcaaaaat atttgcaaaa tctagtgaag atataatctc tataaaagaa
     3421 tcgttaaaag aaagattaaa aatctcaatt ccatatatag aagaatcaaa aattctattg
     3481 ttacattgta tgagtgaaag aatagatatt atgaagttat caataataaa actagagaat
     3541 agaatcgtgc tagattcaaa tgaagaaatc gataatgtag tttttatgtt acttcctaaa
     3601 aattcaccaa gttatcaaag acaaataatg agtgaaataa gtggttcatt aatagacaat
     3661 ataattttta ctaataagat aaataaattc tctatagaag agatgacatt agaggtaaaa
     3721 gatatagttt ttaattttta tacaaacaga ttaaaagcat ttatagataa ataaaattaa
     3781 tattaaaaag gaaggttgat actatgagta aagtattgaa tgagaataat atatttttag
     3841 ggttagatag tgtttcaaag gaagaagcta taactttagc aggaagaaaa ttagttgaaa
     3901 atggatatgt aaaagaagaa tatataccag caatgttaga aagagaaaaa gtaatgacta
     3961 catatatggg aatgggagtt gctattccac atggtgtaaa tgaagcaaaa aaagaaatat
     4021 tatcttctgg aatagttata ttacaattcc ctaatggtat agattttgat ggagaaaaag
     4081 catatttatt aataggaata gctggtgttg gagatgaaca tttagaaata ctatctaata
     4141 tagcagtagt tttagatgat gacttaacag aaagactaaa aaattcaaat gacaaacaag
     4201 cttttatgga agcttttgcc aactaatctt aggagggatt taaaatgaaa aaggcgattc
     4261 agtttggagc aggaaatatt ggaagaggtt ttattggaag cttgttagtt aagtcgggtt
     4321 atcatgtagt atttgctgat gtaaatgagg agatattaaa ctcaataaac aaagataaaa
     4381 agtatactat acacataaga gatgtagaat gtatagatga agtaattgat aatataagtg
     4441 cggtttcatc tataaaagaa gaaataatag atgagattgt acaggctgaa ataataacta
     4501 cagcagttgg acctttagtt ttgactaaaa tagcctctac aattgcaaaa ggtataaaag
     4561 ctagaaaaga aaagggatta acaagtaatc taaatataat agcatgtgaa aatgcaatat
     4621 acgcaagttc ttctttaaaa gaagaggtac ttaagtattt aaataaggaa gaagtagaat
     4681 atttagagat gtatgttggt tttccaaact gttcagttga tagaatagtt cctcctggta
     4741 aaaacgaaaa tcctcttgat gtaacagttg aaaattttta tgagtggaat gttgaaaaac
     4801 aaggatttaa aggggaaata ccaactatag ttggaatgaa tttagctgat aaccttatgg
     4861 cttatataga acgtaaattg tttacactga atacaggtca tgctataaca gcttatatag
     4921 gatatttaaa aggatataag actatagaag agagtataaa agataaattt atctgtgata
     4981 tagtcaaaag tgcaatggta gaaagtggag aaggattgat taaaaaatac aattttgact
     5041 cagaagtgca ctataaatat attgataaaa ttttaaatag atttaaaaat ccatatctta
     5101 atgatgatgt attaagagtc ggaagggaac cattaagaaa actaagtgat aaagatagat
     5161 tgattaaacc tttaatgaca gcaaaatcat atggattatc agttgacaat ttgattcttg
     5221 gaataggtgc agcgcttcat tataataata gtgaagatac tcaaagtgta gaattacaag
     5281 agttgataaa gtctattggg gtaaaaaaag ccgttgctaa aatagctaat ataagcaatg
     5341 acgaagaaat tttaaataat atcgaaaaaa gttatatatt tatgaaaaat ttataaattt
     5401 acttgaaaaa aagtagttct gataaagtaa ctataatata ttattctaca cagtttgaat
     5461 tatttgttga ataatagaga attataatat ataattaaaa ggaataaatt aatatattta
     5521 cctgtatatg tttgataata tggttcaaat gtttctacta agctaccatt aatagcttga
     5581 ctacaggagt gaagaagata tagtttatac ttattttaaa ttatatatta agttaattac
     5641 tttgaatttt aagctcctgt ctatgatata gacaggagct tttttagtat tttaatataa
     5701 aatacttaca agaatagata gcaaaattag aacaaatata atttttttat taatataatt
     5761 ttagaaaggg ctaggtggaa gttcaatgaa ggctttacaa gaaaagatat tgagagaagg
     5821 cagtgtttca ggaaatgata tactaaaagt tgatagtttt ttaaaccatc aaattgatgt
     5881 agctttttta aatgaaatag gaagagaatt taaagagaga tttaaaggag aaaaggtgga
     5941 taagatattt acaatagagg cttcaggaat agctatagca tcaattgttt cacagtattt
     6001 tgataatgca cctgtagtat ttgcaaaaaa atcagaatct aaaaatttgg ataaagatgt
     6061 atatgaaact aatgtatatt catttactaa ggcaagagag tattcagtta aagtttctaa
     6121 aaagtacata aacaaaggcg aaaatatatt gatagtggat gattttttgg caaatggaag
     6181 agctgctctt ggacttaaag atttaattga gcaagcagaa gctaacttag ttggagtagg
     6241 aattgtcatt gaaaaaggat ttcaagctgg aggagcactt ttaaaggcta atgatgtaag
     6301 attagagtct ttggcagtag ttgaatctat agataatgga actgtaaaat ttaggtaatt
     6361 tatgatatta tataattgtg tttagcacat attttaacta tgtaattatg gaggattttt
     6421 tatgaggttt tttatagaca cagccaatat tgaagaaata aaagaagcaa atgatttagg
     6481 tgtaatatgt ggtgtaacta ctaatccgtc tctaatagct aaagaaggta gagattttat
     6541 agaggtagtt aaagaaataa gtgaaatagt agatgggcca ataagcgcag aagtaataag
     6601 tttagaacat aaaggtatga tagaggaagc agaaaaatta tctaagatac ataaaaatat
     6661 agttataaaa atacctatga cagcagaagg tctaaaagcg gtgaaagtac tatcaagtaa
     6721 aggtataaag actaatgtaa cgcttatatt ttctgctgga caagctcttt tagctgctag
     6781 agctggagct acatatgtaa gtccttttgt tggtagattg gatgatatat cacaaaatgg
     6841 tcttgattta attgaagaaa tcgttgatat atttagtgta aatagtattg aggctcaaat
     6901 aatagttgct agtgttagaa atccaataca tgttttacaa gctgctagaa tgggagcaga
     6961 tatagcaaca gttcctctta aagttataaa ccaaatgatt aagcatcctt tgacagacaa
     7021 aggaatagat agctttatga aggattggga aggtgctttt ttaaaattat aattataaac
     7081 tacgctttat aagtatatta aagaggttat tatggaaatt ctaagtaata aggctaggct
     7141 attttgccta gtcttatttt ggtgtataat atattgaaac atattattga aatagattaa
     7201 ttttttaagt gaggaggcga aaaatggata aaatattaag agagatacaa agagaagata
     7261 aaaaaaatcc atatactgac caagaacttg ctgaaatgtt aaatgtagct aggtctgaag
     7321 tgatatcagt taggaaaaaa aataatattt tagattcgag agaaagaaga aaaaaaatat
     7381 taataaaaga tatatcaaaa attgtaagtg aaaatcctca aatgtctgaa agaaaaataa
     7441 ctgaaatatt aatagaaaat ggatataata tatcgagaag tgcagtttca aaattattaa
     7501 aagaggaaaa tttaaatcag tcaaagattg ggattaagga taaagaccca gcatcatcag
     7561 gaaagtatgt gaaggtgagt aaagttgtag aagaagatgg atttgaagaa ttgataggta
     7621 taaagggaag tttgaaagaa aaggtaaatc tagctaagtc agcaataatg tatcctccta
     7681 atggccttca tactataata tatggagaaa caggagtagg taaaagtgaa ttagctacat
     7741 gtatgtataa atatgctata aaaaacaaca ttaaagaaga gaacagccca tttatagtgt
     7801 ttaactgtgc agactatgca gaaaatccta atctattgat agctcaactc tttggggtag
     7861 taaaaggtgc atatacagga gcagatgcaa atagagaagg tcttgtagaa caagctaata
     7921 atggaatatt gtttttagat gaaattcata gattgcctgc tgctgggcaa gaaatcttat
     7981 tttcattaat agatagagga gaatttagaa ggttaggaga aagtagttct aatagaaagg
     8041 caaatgttct cataataagt gctacaacag aaaatccaga ttctaattta cttcaaacat
     8101 ttagaagacg tataccaatg gtaataaatt tacctaatat gagtgaaaga ccaaaatctg
     8161 aaagatatga aataataata aagttttttg aaagagaagc aaagcgagta aacaagaatt
     8221 ttataataac taaagaagtt atgtgtgcac ttatgaatta taagtgtact ggaaatatag
     8281 gtcagttaaa gagtgatata caagtaactt gtgctagagc ttttagtaaa tcgatatttt
     8341 ctagcgataa ggtaattata gatttagata gtttaaggga ttatataaaa agtggatatt
     8401 atgattgtaa ttgtaaaaat gaaaagtatt ctgagttttc agttgaggat atatatatag
     8461 atattagtga attggtgagt ggaaaaaata gaattttatc tgataatgag ataagcgaga
     8521 tatataatta tgcagaaaaa gagcttaagg ttttggaaag taagtgcttt tcagaagaag
     8581 agttaaaaaa tgcatttata gaaaagttag ataagaagtt taatgctatt aaaaacaata
     8641 aaaatttatc tgatagaaga agtcgaatag actggggagg acaattaaaa gagtctacac
     8701 tggagataat ggataaggta attgtattta ttaaggagca gtttaagcat gtaaatcaag
     8761 gtctgtactt ggctctagca attcatattg agcatgctat aggtaggata aaagatggaa
     8821 aaactataat aaatccgagt ttagataaaa taaaagcatc aatgccaatg gaatatgagt
     8881 tgtcaagata tataatgggt atagtagaag atttgacaca agtaacattt ccagaagatg
     8941 agcttggata tttggcttat tatataaata aattttgtta taatgaggaa agtataaaag
     9001 ataaagttaa agtagtaata gttacgcatg gtaaagttgg aattgaaatg tctaaagttg
     9061 taaatcatat tttaggtata gaatgtacac taggtataga aatagcactt acagattcac
     9121 catcagaggg gatagagcat gtattagaag agcttcaaaa gatagaagct agaaaaggta
     9181 ttctagttct aattgatatg ggttctttgg taattcttgg tgatgaggtt gaaaaaaggc
     9241 ttggaattag atgtaaaact gtaaatagag tagatacatt attggcaatg gaagcaggaa
     9301 aacttgcaac cattgaagga aaaagtttag atggtataat agctgattta aagaaaaata
     9361 agaattatgc tatgataaat acaaataaat ttagttacag aaaaaacgag tatggaaaga
     9421 aaaatgtaat cattacttta tgtttgagtg gtgtaggtac agctttaaat ttaaaagagc
     9481 atatagaaaa acaaattaag gaatatggca ctttaattga agtaaagcca gttgcttttt
     9541 taaataataa tttagaagaa gagttaaatg atattgaagc tgaatataat attattgcta
     9601 tctgtggaac tattgatata gattataaaa acgtgccttt tatttcttat aatgaggtac
     9661 ttggtaaaaa tggtattaat aaagtattag agcatctaaa tagtaaacaa ccagctttaa
     9721 atattgaaaa ccagttgaat aatttaatac atgaagattt gattttatac aattttgaag
     9781 gaatttcaaa ggagtatata attgatactc ttgtttcaaa acttgaagaa ggtggatatg
     9841 ttgattcaaa gtatatatta agtgtatata aaagagaagc aatgggaagt gttgtaatgg
     9901 cctctaaggt agccgtgcca catggacttc cagaaaacgt tataaagcct gcaatagcaa
     9961 tcgcaaggtt gaataaacct atagtatggg acaataaatt tatggtggat ttggtggtac
    10021 tactggcact taaagaaaat aataagaaag aaatacgaag cttattttca aagattaatg
    10081 accagcatac tttagaagtt ttattaaata ctgaagataa aaatgaaata aaagaacttt
    10141 taagctaatt attagtaccg agaagaaaga caaaaaaatt tgctttagta taaaatttaa
    10201 aattactcaa ttgctaagta gttaattact ctatataagg ctagttctat gaaatttatt
    10261 tatatgattt tatagaatta gcttttttct tggtaaataa aatatatgaa tttatttatg
    10321 taaaaagtaa attttattgg acaattctat gaaaattttt cctatatttc ttataaaata
    10381 tagaatatat aaaaaatata taaaaataaa ttaaattcat aataaataat tttataaaat
    10441 agttgttaaa cataaaaaac catttgtaaa aaacaaaaaa atcatttctc taacaaaaaa
    10501 aaccacaaaa aatataaaaa agtatggcta gttaagtgat taacaagtaa aaattaaaat
    10561 aaaaatcaaa aaaaatttat caatgaaagt cagctaaaat cctggaagag agcattattt
    10621 tcgggaaaac attttctttt gtttcacaaa aaaagccact ttttggcacg caacatgctt
    10681 tatataaagt caagaaaaac taaggtataa gacaaaggca attaggaggt gtaaatatgg
    10741 agtttataaa ttttgtaagt gataaagtta tagaccttaa aatggattgt aaaacgaaag
    10801 aagatttctt taaagaaata cataataaag tttttgattt aggctttgta aaagaagaat
    10861 ttggagaaaa aatattagca agagaaaatg tatttccaac aggtttaaat ttaggtgatt
    10921 atggagtagc aataccacat acagatgcag aatatattaa agagcaattt atatcagtct
    10981 gtacttttaa tgaaccagta gtatttagtt ctatggaaga ccaagatgaa aaagtacctg
    11041 taaatttggc tttcatatta ggacttaatc aaccacacag tcaattatct gtattaacag
    11101 aattaatggg aattatgcaa aataaagagt tagttgataa gttgatgagt tctactgata
    11161 aagaagaagt tttaaggaca ctaaagtctt tataaaaata aaaaagtact aaaaataaaa
    11221 aatataaaaa taaaaattat taggaggaaa taaaaatgaa aaaaatatta gtagcatgtg
    11281 gagcaggaat agcaacatca acagtagttt gtgacaaggt agagagatta gttaaggaaa
    11341 ataatataca agcagaagtt atacaatgca aaatagctga atgtgcaaca aagcaagaag
    11401 gagcagattt aatagtatca acaactatac taccaacaac ttataatata ccagcaataa
    11461 aagcaacagc atatataact ggagtaaata cagcagcatt agataaaaaa atattagatg
    11521 ctttaaaata atcctatcat agatacattg aaataatatt ttataaaaca gaaaaaggag
    11581 gatttataaa tggataaatt attagcagta gtacaataca ttttaaatat gggaccgaca
    11641 gtaatactac caataacaat tgtagtacta ggaatgatat ttagaattaa gtttacaaaa
    11701 gctttaaagt caggtcttac aattggtata ggatttgtgg gtataaactt agttgtaaac
    11761 ctattaacat caacactagg gccagcggct caaggaatgg ttgaaagatt cggacttaat
    11821 ttaacagtaa tagatgttgg ttggccaaca acagcatcag caacatgggc ttcaccagtt
    11881 gcaccaatat taataccagt ttgtttatta gtaaacttac tattattata cttcaataaa
    11941 acaaagatat taaacgttga tatatggaat tattggcact ttatagtagc aggtgcagtt
    12001 ggatatatag taacaggaag ttatgtttgg gctatattct gtgcaatact aatggagtta
    12061 ttagtactgt ttattgcaga aaagacagca aaaaatgttc aggagtttta tgatttagaa
    12121 ggtatagcat taccaactgg ttcaacagct tcatttgctc cacttggata tttagtaggt
    12181 aaatttgttg aaaaaatacc aggaataaat aaaatacaag cagacccaga ctctatacaa
    12241 aaaagatttg gtatatttgg agaaccaatg atgatgggga ttatactagg tataatactt
    12301 ggagcacttg cgggatatga tgtagcagga atattcaatg taggtatatc aatgggtgca
    12361 gtaatgttac ttatgcctag aatggttaga atattaatgg aaggtttaat tccaatttca
    12421 gaatcaataa gagatttctt acaagcaaaa tatggagaca gagaacttta tataggtctg
    12481 gatgcagcag tagcaacggg acatccagca gttatatcaa cagctcttat acttgttcct
    12541 ataacgttgt tcttagcagt tatactacca ggaaacaaag ttttaccatt tggagactta
    12601 gcgacaatac cattttatat ggcatttata gtgtgcttta gaaaaggtaa tatagttcaa
    12661 tcagttataa caggaacaat agtaatagct atatcacttt atatggctac aaactttgca
    12721 gatgttcata cacaattatt acaacaagca aatatgatgc cagaaggaac aacaatggtt
    12781 acaagtatag atacaggtgg aaacttgcta aaatggggaa tattgaaatt atctcaatta
    12841 gtttcttcat ttggaatatt ctaatatgta gttaatagag attactcttt tttagtaaag
    12901 tatgcgaaaa tttaacattt agcagctact aaaaaagagt aatatttttt ataaattttt
    12961 aaaaatacaa aatacaagag gaggagattt atcgtgaaag cagcagtatt acatggcaca
    13021 aatgatatga gatttgaaga tatagaaata aaaccatgtg aaagtgatga agtaaaaata
    13081 aaagttatgg cagcaggaat atgtgggtca gatcctccaa gagtattaaa acattggaaa
    13141 tatccagttc cagctatacc aggacatgag ttttctggag taattgctga agttggtaag
    13201 gatgtaaaaa atgtaaaagt tggagataga gtagttgcaa ttccttttat accttgtaat
    13261 gaatgtgaat attgtaaaag aggattattt tcattgtgtg atgaccatgg aatgttagga
    13321 gctaaaagtt ttggagcttt tgcagagtat gtaaatataa aagctacaaa tgtacttcca
    13381 ataggagata tggactttga agatgctgca atgatagagc cactagcagt tgctatgcat
    13441 ggagtactta atataggtgt tcaagttgga gacgctgtag ccgtaatggg tagtggaaca
    13501 atggggcagt tggtaataca aggacttaaa atagcaggag caggaacaat tatagcagtt
    13561 gatatatctg ataataaatt aagagaatca aaggaattag gggctgatat aataatcaat
    13621 gctaaagata ttgacccagt agaaaaaata aaagaactta ctggtggaaa aggcgttgac
    13681 atagctcttg aatgtgcagg ttcaaaaata actcaagaac aatgtttact tataactaaa
    13741 aagaaaagta agataggatt tttagggata gcatattcag atataacttt atcagaagaa
    13801 gcatttgaaa atatatttag aaaagaacta gaattaaaag gtttttggaa ctcttattct
    13861 gcaccatttc caggacaaga atggactaag ggaatcaatc tagttaatga aggaaagata
    13921 aaattaaaag aaatggtatc tcatagattc tcacttgaag atacttacaa agcatttgaa
    13981 atgataagag atagaaaaga agaatttaac aaaatattaa ttttaccaca aggggttgaa
    14041 aaataatgaa agcagtagtt aaaactaaac caggctatga taatgtagaa gttttagaag
    14101 tagaagaacc aaaagctaca ggagacaagg ttaaaataaa agtagaatat agtggtatat
    14161 gtggttcaga tatacattca tttaaaggtg aatatgcaaa tataaaagcc ccagtaacat
    14221 taggtcatga attttctgga attgttgtag aagtaggaga agatgttaaa gatataaaag
    14281 taggagatag agttacatca gaaactactt ttgcaacttg tgagaaatgt atatattgtg
    14341 aaactaaaga ttataactta tgcccaacta gaaaaggtat tggtactcaa gtaaatggaa
    14401 gttttgctga gtatgtacta tcaagagaag aaagcataca tgtacttcct gaaaatgtat
    14461 ctttattatc agcagccctt acagagccac tagcttgttg tgttcatgca gctcttgaaa
    14521 agactactat agaaagttct gatacagttt taataatagg accagggcca attggtttat
    14581 tattagctca agttgttaaa tctcaaggtg ctacagttat aatgtctggt gttacaaaag
    14641 ataaggaaag attagaaata gctaaaaatc ttggagtaga tagaactgta aatgtaatgg
    14701 aagaaagttt ggcagatgta gtgaatgaaa tgactgatgg aaatggagta aacaaaggat
    14761 ttgattgttc tgggtttatg ccagcagtta acgaagcctt aagactgctt agaaaaaaag
    14821 gtactttcgt acaagttgga atctttgcta aaaaattaaa tgaaatggac caagaagcaa
    14881 taatccaaag agagttacaa tatataggaa gtagatctca aaagccaagt tcttggatta
    14941 cagcattaga tttaatggca agtgggaaag taaatacaga agctttagtt actagaactg
    15001 ttggtttaga cgaatttaaa gaaggtatta cagctttaat gaacggggaa gaaataaaag
    15061 tagcagtaaa atcttaaaaa aacatttgta ttattttaaa aaaaattgta aaatctactg
    15121 taggataaaa aaatgtaagg tcttaaaaaa taacaggagg aagaaagtat gagcactctt
    15181 agagatcatt ctaataatat tagaaaaaac ataataaaaa tggttgcaga agctaaaagc
    15241 ggacatccag gtggttcatt atcaatagct gatatgttga cagtattata ttttgataag
    15301 atgaacgtat gtgcagaaaa tccaaaaatg gctgatagag atagatttgt tctatcaaaa
    15361 ggtcatgcag caccagcttt atatgctaca ttagcagaaa aaggattttt cccagaagaa
    15421 gaattaataa cactaagaaa atttggttct aagttacaag gtcacccaga catgaaaaaa
    15481 gtagcaggaa tcgatatgtc tactggttct cttggtcaag ggctatctgc agcaaatggt
    15541 atggcacttg caggaaaatt agataacaaa gactatacag tatatactat attaggtgat
    15601 ggagaaatcc aagaaggtca aatatgggaa gctgcaatga cagcatcaca ttacaaatta
    15661 gataatttaa ttgcatttgt tgacttaaat ggattacaaa tagatggttc taatgaagaa
    15721 gtaatgaatg taaatccagt agatgacaaa ttcaaatctt ttggatggaa tgtaatagta
    15781 ataaatggac attcttttga agaaatagga aatgcagttg atgaagctaa aaaagttaca
    15841 ggaaaaccaa ctgtaataat agctaaaaca gtaaaaggta aaggtgtttc atttatggaa
    15901 aataatgctg catggcatgg aacagctcca aatgcagaac aagcagagca agcattgaaa
    15961 gatttagaag gaggtctata ggaatgggaa tagcaactag agaagcttac ggacaagtgt
    16021 taaaagaact tgcagaaaat aaagatatag tagtattaga tgcagattta ggaaaagcta
    16081 caaaaagtat atcatttaaa gaagttgccc cagatagatt ttttgacatg gggatagcag
    16141 aaggtgacat gattggtaca gcagcaggtc ttgctacttg tggaaaaata ccttttgcga
    16201 gtacttttgc aatatttgca gcaggaagag gctatgagca aataagaaac tctgtagcat
    16261 atccaaattt aaatgtaaaa atagcagcta ctcatgcagg tgtaacagta ggtgaagatg
    16321 gtggtagcca tcaagctata gaggatatat ctctaatgag aggtatacca aatatggttg
    16381 tattaaatcc agcagatgct ttagaagcaa gacaagctat tcttgcatct attgattata
    16441 atggacctgt ttatataaga ttaggtagag ctgcaactcc tgatgtaaac agtgaaaatt
    16501 ataaatttga aataggaaaa ggaactgttt taagagaagg ttctgacata acagtaatag
    16561 ctacaggaat aatggtagca aaagccttag aagcagcaga agaacttgct aaagaaggta
    16621 taaatgtaga agttgttaat atatctacaa taaaaccatt agatgaagca ttaataaaag
    16681 aaactgctaa gaaaactgga aaagtagtta cagcagagga gcacagtata ataggtggtt
    16741 taggttcagc tgtatgtgaa gctttagcag aaactaaaga tgtagtagtt agaagaattg
    16801 gtgttaaaga tgtatttggt caatcaggta caccagctga tttattaaaa cactatggtt
    16861 taactacaga agatatagta aaaaatataa aagagttgtt atagatataa atatatctaa
    16921 ataacaaatt gatttgacat aagtcaatta aagctgtctt aaaaatagaa agaaatttct
    16981 acaatgggac agctttattt ttacaatact ttatttttat gataattata aaatagtctg
    17041 aaagtaatca aaaaaattat aaaaagaggt gctatttaat gaaaatatct attggatgtg
    17101 accatggtgg ttatgaatta aaggaatata taaaggaaaa tttaataaat aaaggtatag
    17161 aagttgaaga tgtgggtaca aattcaaaag aaagtgtaga ttttccaata tatgcaaaaa
    17221 aggtaagtca aaatgttcaa agtaaaaaat ctgatttagg catactttgt tgtggaacag
    17281 gaataggcat gtctattgca gcaaataagt ttaaaggaat cagagcagct gttgtttctg
    17341 actgtttttc agctaaggca actagagaac acaataatac aaatgtactt tgtttaggag
    17401 aaagagttat tgggaaagga ttagcaatga gaattgttga agaatggtta aattcaagtt
    17461 ataatggaga aagacatgca agaagattac aaatgattga tgatatagaa aaagaaaatt
    17521 tataaatata tataatatat aatttataac aagggggagc gttatgtcta ttatttgtgc
    17581 ttcaataatg tgtgcagacc aaatgaagtt aaaagaggaa ttagaagctc ttgaagaagc
    17641 aggtgtaaaa ttacttcatt gtgatgttat ggatggaata tttgttaaaa acttggctat
    17701 gggaccagag ttattaaaat caataagtga aaatacaaca atacctttag acatacactt
    17761 agccacagaa actccagata aatatattga tatgatgtct tatataaagc caaaatatat
    17821 ttcttttcat gtagaatcaa gtacaaatgt aaaagctgat atacaaaagt taagaaatta
    17881 tggtataggg ccagtgttag caataagccc tcaaacaagt gtggataaaa tagaagaata
    17941 tataagttta gttgagggta tcttagtaat gacagtaaat ccagggtttg caggtcaaaa
    18001 gtttaatctt tctgtattgg ataagttgga taaacttaca gagatactaa aagattatga
    18061 taatcctcca tttatagagg ttgatggaaa tataaataag gatactatta aacttatgaa
    18121 tggtaaaaaa gtagatatat atgttgttgg tacttcagct ttatttaatg ataagcctcc
    18181 aatttcatat aaagataaaa tagaagaact aaaagaaagt ataaagtaac catgtaataa
    18241 aattataata tgtttctgtt taatagtaaa aatttaggtg gaaacaagaa attttataat
    18301 atttaataaa aattttggtt gagtaaggag aattttttat gggagaccta tataaactac
    18361 aaaatggtac tgatattaga ggaatagcgt atgaaaatga ttctaaagaa gttaacctaa
    18421 ctgtagaaga agtaaaaaaa atagctaaag cgtttcatat ttggctaaaa gaaaagacta
    18481 agaaagataa agtaactgtt gccataggaa ctgattctag gataacagga agccaattta
    18541 gaagtactgt tattgaaact ttaactaatg atgattgtaa tgtaattgat tgtgagattg
    18601 ctacaactcc agctatgttt atgacaacta ttatggatgg atacaattct gatggggcga
    18661 ttatgattac agcaagtcac ttaccttatt actataatgg tttaaagttt ttcacagaaa
    18721 gtggaggttt agaaaaaact aatataaaag agatgttgga tatagctgtt aaaaatgata
    18781 gtgtagacta tgaggaagta aataaaaaag gtgaagttat agtaaaaaat ttaatagaag
    18841 attattctaa tttattgata gataaaatta gaaaaggtgt aaattcaagt aaaaattatg
    18901 aaaagccttt ttctgggctt aagatattgg ttgatgcagg aaatggagct ggtggattct
    18961 ttgctgaaaa agttttacac atactgggag cagatacgac aggcagtcag tttttgaacc
    19021 cagatggtat gttcccaaat catataccta atcccgaaaa caaagaagca atggaaagca
    19081 tatgtaaagc tgtgttggat aataatagca acctaggaat aatctttgat acagatgtag
    19141 acagagctgc tattgtaggt aaaaatggca aaccaataaa taaaaatgct cttatagctg
    19201 ttatatcatc aatagtatta gaagaacatc caaaaacagc tatagtaaca gattcgatta
    19261 cttctgaagg acttgctaaa tttataaatg aattacaagg aagacatcat agatttaaaa
    19321 gaggatataa aaatgtaata aatgaagcta taagattgaa tagtgaaggt gaagagtgcc
    19381 atttagctat agaaacgtct ggacatgctg ctttaaaaga aaattatttc ttagatgatg
    19441 gggcatattt aatagctaaa attttaataa aagtagcaaa gctatccttg gaaggaaaga
    19501 ctatagaaga attgatagaa aaccttgaag aagctcaaga agagaaagaa gttagaatag
    19561 gcattaacaa agaagatttt agaccatatg cagaggatat attaaaagat ttagattctc
    19621 atgttaagag tattgatgga tggtctgtag caccaaataa ttttgaagga ataagagtta
    19681 attgtgatga atcaaatgga gatggatggt ttttacttag aatatcacta catgaaccat
    19741 tactagcttt aaatattgaa tcaaataaaa ttggtggagc agaacaaatt tattctaagt
    19801 taaaactttt cttagaaaaa tatgatttaa aaggtcttta gggtaaatag aaagaatata
    19861 tttatattaa agaacaaatg taaatttgta cctaagatta caaatattac aaaattgtaa
    19921 tcttaggtaa cagagatgta actgattatg gaaacactat gtgatattat agatacagag
    19981 agatgaaata tgtgatgaat tatagagaaa tataatttaa aatgtattaa tatcacacca
    20041 aaaaggtata atcaaaaaat atgtaaatat aaaccccaac atttagaaaa agacctctaa
    20101 ggaggttttt ttcttgttta aataacttaa aatatatttt tatattaata tatcaattaa
    20161 ctcttctaaa agtaagcatt accttaaata aatcagcatc tataattatt tccatgtgtg
    20221 cattttctaa ttcaattata ttttgagcaa ttgataaacc aagaccagag ccatctgttt
    20281 ttctagatat atcacccctt ctaaatcttt ctattaactc ttctggcttt agatttagtt
    20341 tatcatttga aatattttta aacgttaata ttatattttc ttcctttata aacatatcta
    20401 tatagaccct agtgttaggc atagagtatt ttagtatatt gcaaattaga ttctcaaaaa
    20461 ctctccaagt ttttttacca tctatcatgg taaaaacagc atattcaggt gtttctatta
    20521 taaaatctaa actgctattt tgaattttgt cttcaaactc tacaatactt tgaattaaaa
    20581 gttctcttat atcggttttt gttatattaa attctacatc tccactactt agcttagatg
    20641 cttcaaatat gtcatctatt aataatttta atctttgtga ttttttatct aaaatattta
    20701 tatagtcatt tatagtctct ctgtcaaagt cattattttt taacatatca acatagctta
    20761 atatagatgt aagtggagtt tttaagtcat gagatacgtt tgtgataagc tctgccttca
    20821 tcctttcatt ttttatatta gcatctacag cagtttcaag accacctgtt atattattta
    20881 tacttttggc taaagtagat atttcatcat ctcctataac ttctaattta tactttaaat
    20941 tgccattttc tatatttttt atattttttg atatgttatt tatgtaatta aacttaacag
    21001 ataaaaagtt gtatatataa aaatgaaaaa ctgtgtttac aagtgtaaat aaaattacta
    21061 tagctattgc ctcagaataa tatatataca taaagaatat caaaacaaga tattggataa
    21121 tagcttgtac aactatagat attaaaaata ctatagctaa ttttttattt atagtttttt
    21181 tattatacat actaagtaag tttgaaaaga atacatatgt tatagacata tcttttagat
    21241 tatagttatt atatttaata ttttcatata ttatatagac tatagatata attataaaat
    21301 tgtagattat taaattagtg ttgtaaaaca ttttattact tgtaaatgca tgaaacctta
    21361 aggttaatag tatcaaagtt aatataagtg taagttctat ttttacctta gaaaaaaggc
    21421 ttatgacatt ctctaagaat ttgactttag tctgtttatt ttttttatac aatgtaaaac
    21481 atagtatagt caataaaaaa cttgataata taatacctat gcagacaaac tctaattcta
    21541 cttttgacaa atgtacagga gtaccgaaaa aataaaaata agggagagca aactctttat
    21601 aataacaatt aatattataa gaaaagttat tattcaaatc ataaactgct tcaaataata
    21661 tagaaactaa tagaaacagt aataataata aaataaattt tgctttagaa tcattaataa
    21721 ttaagttttt caattttgta accaatgccc cacaccacct ttaaatattt tggttctttt
    21781 ggattaattt caattttttc tctaattctt ctaatatgaa cagcaatagt tctctcacaa
    21841 ctataagcat cttcattcca gacattttca taaatttcac gggaagagaa aattttacct
    21901 tttcgtgaca taagaagtgt aagtatttta tattcaagtg gtgtcatttt aatttcctca
    21961 ccatctaaag aaactatttt tgtatctgta tttagctcta ggccaccact ttttagaata
    22021 taattagtat catttgagtt atttgtatta ctaaaatcac ctaaatttat ataccttcta
    22081 agttgagatt ttactcgagc agtaagttct agtggattaa atggtttagt tatatagtca
    22141 tcagcaccca tattaagacc tataattttg tccatatctt ctgattttgc agataagaga
    22201 attattggta tattcctttt ttctcttatt ttaagtgtag ttttaagccc atctaaattg
    22261 ggcatcatta catccattat tattaactta atatcatttt cgattagtat gtccaatgct
    22321 tcaagtccat catatgcctt taaaacatta aagttatcag gtctcaaata gaactctata
    22381 gcatcaacta tctctctatc atcatctaca accaatatat tttgattcaa tttattaacc
    22441 cccttgaaat tttattttta accaattttt attttatacc aaaaagaggt attagaaaac
    22501 agtaagcccg ttcattatga aataaaaact agtactttta atatattgtc aatgcatata
    22561 gtaaatttaa aagtatagac gcccatatta atctgaaggt aaaagtttat gaaaatatct
    22621 agggtaatct atcacactcc ttatgttatt ttgggtttat taatttttta ggtttaaaca
    22681 tatattaaca aatataaata acaaatgagt ttcataatta ttaagaattt ataacaaata
    22741 tttattttaa tgtagtttaa tataaatagg tagtttaatg tagatatgta taaagtattt
    22801 aataaggctt ataggtttta atgatgatat ctttatatat tttaagagat gatgaaatta
    22861 gatatgggta atagttgaat gagaaaaagt agtatagcac aaaaagtgct atatcacaaa
    22921 atctcaaata atttccttct tataacttaa attaaaagaa taaatatttc ttataaatta
    22981 ggtgtatgaa gtatagcagg aacatcttta ttatttaata acttatcaaa tgatttatgg
    23041 tcagacttat agccaatacc ttctctatat tctaattcat caacaatttt gtattgttga
    23101 caggcatttt taaccttttc atagtcttca gtagaatgag ctttataaac tatcttatta
    23161 ttaaaagtta ttttatcagc aaatttaggt tttacaaaat atttagcatc ttttatttta
    23221 ccaacattat ataaattttg gataacagaa ccatttttta aatgttgtaa atggtcatct
    23281 aacttataag tatgtgctat atgagttaca tttttaaatt tttcttcaaa tgtaagagca
    23341 attttttcca tgtaattgaa gtcagtatta ccatttgtat ttgtttctgg taataatatt
    23401 atattttccc ttattacacc aaggctatta agagaagcta aaaattctct atttctatat
    23461 tctgattttt gtatatttgt taggttttca tattttttat atttatcaaa gacggatata
    23521 ccacatccag tagatactaa aactacaaat acatgatttt ttcctctttc ttttatagca
    23581 ttaacaatag cactcccagc ccacaacact tcatcatctt gatgctgaac atagaagaca
    23641 acataatctt taaatttttt atgactataa ttcacatagc tactaaaacc ggttaaaatc
    23701 aagcataaaa ctagaataat agatagaatt tcatatttat ttatagtaaa ttttttattc
    23761 ttaaatgtca tttaatcatc tcctgaaaag ttgtcttagt tatattatca aacaaagtac
    23821 taaaaattat ttcttaaatg ctgaaaaata tagagtagat taatggaata aaattttttt
    23881 tattagttta aaataaagaa aacatttatg tataagacta atcaaaatat taataattga
    23941 taggaattga gatttaaagg gattgtacat ttattcggga ttcattttaa tagaatttta
    24001 ctttagtact tagaataaaa gtaataactt tttaaattta aagagtacac atatatattt
    24061 gtgtactcct tgatgatatg attgcttatt tactacaaaa acagagtctt tttaaaccta
    24121 aaatatttga tgcaccagct atcgtagttc cataatagta aactggtttg ttaagtgata
    24181 gaaaatttat aattgagtta ttacataatg tacttcctgt gcaaatcact aaatcagccc
    24241 aagatattac atcttcataa tctcgtatac catcttcaat cttaacatta tattgaatag
    24301 tatccacaaa ttcaggattt aaatctaata ctcttgtttc gaaaaagtcc ttaatattat
    24361 caattatggc tggttgatat cctataattg ctacttttgg attaccaaat tccattttta
    24421 taaactcagg gaattttttt gcacatacct ctggctcgtt atttttacaa tgaatggttc
    24481 tatccgtctt gcctaagtat ttcataactg catttaatga tgctataaaa agacttctat
    24541 catgaggatt gtcatgtaaa tctaatgata atatgtcttt taaagaacct tcaaatgtag
    24601 atggagtaga agtaaatgct tgtcctttag ctcctttaaa gtcagcttca agcattattt
    24661 ctttaccaac tataattggg aaatctttac gcttagtatt tccaattgct tcttttgaag
    24721 atagagattt ggacacaata cttatcatat ccatatttaa attatattta tcgacttgta
    24781 ctaatagata atctctcaaa atatcaaata tattcataga aaaaagattc tcctttattt
    24841 tttatttctt catttaaatc aaaaatatga tttatttttc cattgttcat tattcctatc
    24901 ttatgagcaa aaaacattgc ttcagaaata tcatgagtaa catgaatcac tgttggtttg
    24961 tattttatgt agacatcctt caaaattttg cttatatgtt tttttgtaat ataatccaat
    25021 gaactcatag gttcatctaa aagtaatata tcaggttcag ctattaaggc acgtgcaaaa
    25081 gcaactcgtt gcttttcgcc tccacttaaa tttttaggat acctattttt tatatcttct
    25141 atctgcatta atttagacaa gtggttagcc ttaagaatct gttcatctat aggtattttt
    25201 cttaatttaa gtggaaacct tatattatct tcaacattca tatttggaaa taattcaaaa
    25261 ttttgatata caaatcctat atttctattt tctggaggta agtttgatat taaattttct
    25321 ttgtatgata catttccttt agcagatgga tatcttcctg ctaatgtttc taggaataga
    25381 gttttacctg acccactagc tcctaataaa acaaagtatt catgattatt aatatttaaa
    25441 ctattttctt gtaatttaaa attaggtaaa tcaagagata aattttttat ttttaacata
    25501 ttaattctta tcaacctctc tattaaaaaa tatctcaaaa agcatcaagc atgtaagtga
    25561 gataaatatc aaaattacag ctattccgat tgcaatgtct atatcaccag tagacatatt
    25621 taaatatata gatgtaggaa taatttcagt tttcatacgt gtagaacctg ctatcatagc
    25681 tactgcacca aattcaccaa gtgctcttga ccaagtcatt acagttgcag atatgattcc
    25741 agtttttaga tttggaagaa ttataaatct aaatgcttcc caactattac atccaagggt
    25801 acgtgcaaca aatatcatct tttcattact ttcatttagt gaagtgtgaa gtattttaat
    25861 agtaagtgga agatttacaa atacttgtgc taaaactata ccttgctttg taaatataaa
    25921 atcaagctta aaaatcttat aaatggaatc tccaatcccc attcttccaa acaaaagtaa
    25981 aagagcaatt cctgatacta agtgtggaag agacataggg agatttatta tctgtataat
    26041 cagtttttta aatggtaatt tagtaatatg taaaaaatat gctactggaa tagctaataa
    26101 aaggcatact atagtagata ttaaagatgt tttaatacta agtgttattg catactgtac
    26161 ttccacggat tttaagcata taggaacata acttatccct ttaatgatta acataagaag
    26221 tggtgataca ataaaaaaaa agactatagc aaaaaatcca gtaagtagtg tagtaaaaaa
    26281 tttatttttc aagtttaatc actacttaac aggttcaaaa ccatattttt taaatatctg
    26341 tttagcttca tctgactcta tataatttat aaatttatta gctaaatctt ttttatcact
    26401 atagtttacg attcctgctg atatgagttg gtctatattt ttatcttggg caatttctat
    26461 aacttctaca tcttcattgc caaagaccga atcttttgtg gctattgtag catcagcttt
    26521 acttgatgtt aactgtacaa tcatttcatt tacagttgca gctgtagaga caacattatc
    26581 atttatagat tttaaattat ttttttcaag tattttttgt gtagtcttac ctatagcatt
    26641 agactctttg tctcccaaaa taagtttaac tccatcttta tttaagtctt ccaatttttg
    26701 aatattagct ggatttcctt taggtacaac tattgcaggt gtatgatgtg caaccgtttt
    26761 atgttcacct acaagttctt tttcaaaggc ctttgaataa attggttcag aaccaacaat
    26821 aaatacgtct cctttgtgac ttgtctcaat ttgagctatt agctgtgcag aacctgcata
    26881 gctatattca actttgacat tattttcttt ctcaaatttt tttgctattt catccattgg
    26941 tttctttaaa cctgcccctg aatagacaaa aagagtctct ttttcttttg aatcatcagc
    27001 tgttgtcact ttagtattag attcatcatt agctttgttt tctttagaat tacatgcagt
    27061 aatacttaat gaaataatca tagctaaagc tagtactgaa agttttttaa acataagata
    27121 ttccccctta gtaaattagt gtaaattctt ttttagtata tcatactaag aaaacgatgt
    27181 ctaagttttt gttatgtttt ataatgtttt gttatgtttt attatgtata gttaagaaaa
    27241 aatctattta taatgtcatt tccataggta gttattttat ttttaatttt tattaatact
    27301 ttaaagtatt ttaaatttaa aaacttaaat caaattaact tattgtagat tttttacttt
    27361 ttaactaatt ttatatttat tatatttcag tgaaaaaata gaacattgaa acatatagat
    27421 atgttttaat tgctttttat taacaaatta ctaaaagtgt tatatcagaa ttgaatacaa
    27481 aagaaagagt atgtatttat gagatagttg aaaattttga tgtgccacaa ctaaaattat
    27541 tatattacta tatattctaa ttaaaagagt acttgtaggt ttaagtacat actttataaa
    27601 tatatttttg tcagatttat tttataaaaa gtatttagac taagtattat ttttaagtat
    27661 tttcttgttg aagttatttt ttcctttttt acaaaatgcg taaataaaaa aaagactctt
    27721 aaaagagtct ttccgaaaaa tctatatatt ataatatagt tatattttct gcttgaggac
    27781 ctctagcgcc tttaactata tcaaagctta ctttttgacc ttcttctaat gatttaaatc
    27841 ctgaagtttg tatagctgag aaatgagcaa atacgtcatc tccactttcc attgatataa
    27901 atccaaatcc tttttcatta ttaaaccatt ttactattcc attattcatt aaaaatactc
    27961 ctattaacct atatcaagat atacttgatt tacttgtgta ttaccacaaa tactattata
    28021 tcatagatta acataaatgt ctatttaatt ataattttta gttaacattt ttatttattc
    28081 ttaatatgaa aataaattta aacattttat attaccaata tattaatgta aatgtagata
    28141 aaactaaaaa gggttttcta gaagaaaatc tgtctaatta tacttactta ccaataccat
    28201 cacttgatgc aagcaagatt ccacaacttt ttctccgtac tctaatataa aatcatctaa
    28261 ctgtgtatct ataaaatcac aataatcata tgaactacca atataagcag ttagcatatg
    28321 tgtacattta tccattttat ctctaaacat aatgtattta tccccctaaa aaactttcat
    28381 gaaaaacaaa aagaaaatat ctttttggca actggctgac ataacttatt ttataagcgt
    28441 tagtccctat agctttgcgt cactaaattt ctctagtttt gccgatttag ttttattcta
    28501 cagattaata atacaataga attagctatt attcaacata tctagctgaa aaattaataa
    28561 atttatatat gaacgttaaa ttatttgaaa aaataaaaag cccctctgtc tgaactatac
    28621 ccctcttagg agacagttga aatatgtaaa actgtctaaa actaggaggg ttttgttatg
    28681 tctaaaacta aagtatcatc agagcaaaaa atcgaagcaa ttgaatcata tttaaagggt
    28741 gaaaattcag taataaaaat aatggaagaa ttaaatattg gaaaacgtac attcagagag
    28801 tggatgcgaa attatgaaac ttttggaaat gatggtttaa taaaacaaag tcacaaatca
    28861 tgctattcta aagagtttaa attaaatgct atagaatctt atctaaatgg ggaaggatct
    28921 tatgacacta tctcaaaaaa atataaaatg aggtctgtta atccactaaa agcttgggtt
    28981 a
//
LOCUS       DAEQJM010000047        28313 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.047, whole genome shotgun sequence.
ACCESSION   DAEQJM010000047 DAEQJM010000000
VERSION     DAEQJM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28313
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.047"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(246..1496)
                     /locus_tag="KRQ43_002523"
     CDS             complement(246..1496)
                     /locus_tag="KRQ43_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HBH2742873.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLYEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDSDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1528..2469)
                     /locus_tag="KRQ43_002524"
     CDS             complement(1528..2469)
                     /locus_tag="KRQ43_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBH2742874.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2709..3785)
                     /locus_tag="KRQ43_002525"
     CDS             complement(2709..3785)
                     /locus_tag="KRQ43_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH2742875.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(4158..4673)
                     /locus_tag="KRQ43_002526"
     CDS             complement(4158..4673)
                     /locus_tag="KRQ43_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HBH2742876.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(5036..6106)
                     /gene="leuB"
                     /locus_tag="KRQ43_002527"
     CDS             complement(5036..6106)
                     /gene="leuB"
                     /locus_tag="KRQ43_002527"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBH2742877.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDEIGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTRAMGELIVNEI"
     gene            complement(6113..6604)
                     /gene="leuD"
                     /locus_tag="KRQ43_002528"
     CDS             complement(6113..6604)
                     /gene="leuD"
                     /locus_tag="KRQ43_002528"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBH2742878.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKEKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(6619..7896)
                     /gene="leuC"
                     /locus_tag="KRQ43_002529"
     CDS             complement(6619..7896)
                     /gene="leuC"
                     /locus_tag="KRQ43_002529"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBH2742879.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTITKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(7853..9595)
                     /gene="leuA"
                     /locus_tag="KRQ43_002530"
     CDS             complement(7853..9595)
                     /gene="leuA"
                     /locus_tag="KRQ43_002530"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBH2742880.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIKGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(9719..9965)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10113..10559)
                     /locus_tag="KRQ43_002531"
     CDS             complement(10113..10559)
                     /locus_tag="KRQ43_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742881.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(10580..11299)
                     /locus_tag="KRQ43_002532"
     CDS             complement(10580..11299)
                     /locus_tag="KRQ43_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH2742882.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYSGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGTRVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(11417..12691)
                     /locus_tag="KRQ43_002533"
     CDS             complement(11417..12691)
                     /locus_tag="KRQ43_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBH2742883.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(12891..14258)
                     /locus_tag="KRQ43_002534"
     CDS             complement(12891..14258)
                     /locus_tag="KRQ43_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2742884.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIRYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(14508..14972)
                     /locus_tag="KRQ43_002535"
     CDS             complement(14508..14972)
                     /locus_tag="KRQ43_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBH2742885.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(14977..15606)
                     /locus_tag="KRQ43_002536"
     CDS             complement(14977..15606)
                     /locus_tag="KRQ43_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH2742886.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADKVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(15640..16527)
                     /locus_tag="KRQ43_002537"
     CDS             complement(15640..16527)
                     /locus_tag="KRQ43_002537"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBH2742887.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYSLYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(16556..17794)
                     /locus_tag="KRQ43_002538"
     CDS             complement(16556..17794)
                     /locus_tag="KRQ43_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742888.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYNL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(18178..19320)
                     /locus_tag="KRQ43_002539"
     CDS             complement(18178..19320)
                     /locus_tag="KRQ43_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH2742889.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            complement(19461..20327)
                     /locus_tag="KRQ43_002540"
     CDS             complement(19461..20327)
                     /locus_tag="KRQ43_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH2742890.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            complement(20661..22208)
                     /locus_tag="KRQ43_002541"
     CDS             complement(20661..22208)
                     /locus_tag="KRQ43_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH2742891.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            complement(22201..23337)
                     /locus_tag="KRQ43_002542"
     CDS             complement(22201..23337)
                     /locus_tag="KRQ43_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742892.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            complement(23593..24690)
                     /gene="dinB"
                     /locus_tag="KRQ43_002543"
     CDS             complement(23593..24690)
                     /gene="dinB"
                     /locus_tag="KRQ43_002543"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBH2742893.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGKPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKSSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            complement(25080..26585)
                     /locus_tag="KRQ43_002544"
     CDS             complement(25080..26585)
                     /locus_tag="KRQ43_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBH2742894.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            complement(26847..27197)
                     /locus_tag="KRQ43_002545"
     CDS             complement(26847..27197)
                     /locus_tag="KRQ43_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742895.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKTVTSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            complement(27420..27611)
                     /locus_tag="KRQ43_002546"
     CDS             complement(27420..27611)
                     /locus_tag="KRQ43_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742896.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            complement(27730..28278)
                     /locus_tag="KRQ43_002547"
     CDS             complement(27730..28278)
                     /locus_tag="KRQ43_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2742897.1"
                     /translation="MGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKADIEPVL
                     LKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGDAEEERLSEFI
                     NGNTLKYDFVKMPHHGRYDKLTETFLESTSPQYAVITCSEKKEPEEGVLKILERLNIK
                     TFLTSSGEVVINSDGKTLSVNQ"
BASE COUNT         9204 a         5120 c         2934 g        11055 t
ORIGIN      
        1 atatataaca atactattat aaatacatat ttaaaacctt ataaatatac aaatacaatt
       61 atatgaattt tcatcctcaa ttatagcata gaatatgact atctatatcc taaaattatc
      121 catttctaaa aaaaggtaac tattattaag aatatcaact tatagaattt atattccaca
      181 tacgattttc aatcaaaaaa acaagggcta aaaagtgaat tgtacacttt ttagcccttt
      241 attaattatt catttatttc atgtaagaat agcccacatc ttactttagg ttcaaaccat
      301 gttgacttag ctggcattat cttatttgca tctgctactc ttattaaatc ttcaatacta
      361 gtaggataca ttgcaaatgc tactttcata tcttcattaa ctcttttttc taattcttca
      421 agacctctaa ttccaccgat aaaatcaatt cttttatcta ctctaggatt gtcaattcct
      481 aaaatagcat caataacata gtcttgtaat atagaaatgt ctaatgagtc aacagggtct
      541 tctatttcta ataaattttt atttgctttc attttatacc acttatcacc taggtacatt
      601 ccgaaagttc cttttttgtc aggtttatat ttttcttttc cttctatttc ttctagttca
      661 aaattttctt ttattttatt tataaattct tcctcgctta aaccatttaa gtctttgata
      721 accctattat aatccaaaac cattaaattc tcatctggtg caatcattgc tatgaagtaa
      781 ttaaattctt ctttgccagt ataatttgga tttttagctc tcatttcttt ggctacattt
      841 tctgctgaag ctgtcctatg atgaccatct gcaatgtata gataatctaa tttttcaaat
      901 ttatctacta ggttatctat tatatcatca ctatcaatct tccatactgt atgctctatc
      961 ttgtcatctg ttatgaaatc atataaaggt tcattattat ccataaaatc attgattata
     1021 tcatctatca ccctttgatg tttgtaagtt acaagtatag ttcccgtatt agcatcacag
     1081 tattttatgt gtttagttct atcaatttcc ttttctggtc gagtgtactc atgttttttt
     1141 attgttccat tcaagctttc atcaactgat atacatgcta ctataccaac ttgagctcta
     1201 ccatccatga tttgtttata tatatatata cactctttgt catcttttac tagaatttct
     1261 tgttttcgaa actcatataa attttctcgc gcttttaaat aaactttttc atcatataaa
     1321 tctatatttt catctaaatc aatttctgat ttatctatat gcaaaaatga atatggattc
     1381 ccttctgcaa ttcttctagc ttctttacta ttcataacat cgtaaggaag tgctgctact
     1441 ttatctacta tatatttatt tggtctaatc gccttaaatg gtttaatcgt tgccattact
     1501 aatttcctcc taattataca aaatatttta taatgctacc cctattagat tgttgaagtc
     1561 aagaaagaaa tcttgaatca catttactat ttcgtctcct attctttctt gagcttctac
     1621 tgtagatgcc ccaatatgag gtgtaggaga aactcttgga tgatttacta agtctaaatt
     1681 taatgtaggt tcttgttcat aaacatctat agcagctgct gataatttac cttcatctaa
     1741 tgcttttagt aaatcttttt catcaactaa accgcctctt gcacagttta ttaaataagc
     1801 ccctttcttc atcttattta tttctttttc agttattact gcccccttat tcttatcaaa
     1861 tggtatgtgt aaagataaga aatctgcatt ttctaaaact tcttccatat cacagaattt
     1921 ataattgtta aaaccttgcg cctcacccat tatgtcagta tatataacat tcatacctaa
     1981 taattctgct ctctttgcaa cttcttttgc aattcttcca aaacctataa gtccaagtgt
     2041 ctttccatta atttctgtac ctttatactt cttcttctcc cattttccat ctctcatagt
     2101 tacatttgca gtatttatga atcttgcaag aacaaataat tgacctattg taagctctgc
     2161 aacagatata ctgcttgcat ttggagtatt cataactttt atgccattag cttgagcata
     2221 tttaacatct atattatcca gacctactcc acctcttact atcaacttca actttttacc
     2281 ctctaatgct ttatctatta catctttagt aactttagta gctgaacgta ctacaagtac
     2341 atcaacatct ttaagtttat ctcctaaaac atctttttca taaaactgct ctatcacatt
     2401 aaaatctaac tctctcaatt ttctcgctgc ttctttctct attccatcag taactaatat
     2461 attatacata acaaactcct ccaattttta ttcacttaat ttttccaatt tttatttttt
     2521 aaagtatttt catcaataaa aaactttact taatttaact ttctgtttat ataattttca
     2581 aaatattttt ttattaaagt catatcaaat tttcctattg tttgttaaaa atttaatatg
     2641 taatttttat aaaatattat ttattatata ttctaaattt atcttaaaac atacatattt
     2701 ttacaatatt atttattaaa acctaatata tcatcaatat tatctaataa ttcttgtaca
     2761 tcttcgacag tatagtcacc catatgtgaa attctaaaag ttttttcttt taaatctcca
     2821 tagccatttg ctatttggaa tcctcgttct tgtaattttg aatttaaatt tgatacacta
     2881 ataccttgag tattttctat aacagtaagt gtattggata agtgattttc attggtaaaa
     2941 atttggaagt gttttttagc ccagtttcta actaagtttg ccatgtcttc atgtctgttg
     3001 aatctgttat ctaggccttc atctaatata ttatctaatt ggaaatctaa agcgaacatg
     3061 tgagaaagag atggtgttga agggtattgg tagtttttct tgattaagta ttcatacatt
     3121 gctaacaaat caagatatac tcctctaaaa ggtacttgct tagctctatc gattgctttt
     3181 tgagaaaatg tgcaaataga cattcctggt ggtaatccca gtgctttttg tactgatgtt
     3241 atacaaatat ctattccaat cttatcaacc tcgactttta ttccaccggc tgaacttaca
     3301 gtatctacac agtagattac atcttcatac tttttaacaa cttctccaat ttcttctatt
     3361 ggatttctta ttccagttga agtttcattg tgagttacag ttattaaatc gtattctccg
     3421 gtagaaagca ccttatcaac catttctggc gttgttgcct ctcctaattc aactttaaat
     3481 atatccgctg ggacattatt agccactgcc attttgtacc atctatcacc aaaggatcca
     3541 caggaaaata ctgctgcctt tttggatgta caggaacgaa tggagccttc cattaaacca
     3601 gttccggatg acgtggataa aagtatcgtg ttgtttgtat agaatagttt ttgcatcttt
     3661 tcacttatac tcttttggag catagatgca tcttttcctc tatgtcctat cattggtgta
     3721 gccatctttt gcaagacttc ttctttaaca tcaataggac caggaataaa taatttctta
     3781 ctcattataa ttcccccctt tttagtttgt aatatggata gcgtttttac tgtccttatt
     3841 tttaataact ataatatcaa gctgaattaa ctatgtcaac ataaaattta ttttttatat
     3901 ataatttatt ttatatattt tatgaaaaca ttcattttct gccttttcat aagtctgaat
     3961 tttctgaatt attctctcaa aaaaaatata ctttttatct atataaatta atttttttag
     4021 tatgtaaatt tgacgctatt acgataaatc tttttagtat aactaattta tttttatctt
     4081 gtatttttat tgtatttttg aattttattt tttctaaata taaaatttat gttttaaaat
     4141 ataaaatttt tatttaatca aagttcaata tattccactt tttctttcga ttcttcaaaa
     4201 aaccattctt cattagaaaa atcaccttct gcaatttgtc caataggcat tttcatatac
     4261 tttccagttg ctgtcactgc tatatctcca tttggtagaa ttatttctcc tgtaccttca
     4321 aataattttc tgttttcttt agttattctt ccaacaactt ttatagtagc atctgttggt
     4381 actggtttct tatatttcaa ctctaaagat actgttactc cccatatttg gtcatcattt
     4441 atacttacag ctcttccaat agtctcatct aatattgcag cagacatacc tccatgaact
     4501 ctcccaggat aactttgatg ccaatccttt gtattacaaa ttgatacaag ctctccattt
     4561 tcaagttcat aaaaatctgc tttaagtcct agctcatttt gtgttccaca aactaaacaa
     4621 gatttactac tattttgctt cttcaaaact ttatactttg ccaaaaaatc catctcctaa
     4681 ccgacattag tagtcgctta atattaaata attctaaaat atattatata atattaataa
     4741 aatccctgca aacttctaat aataaaaata ggctacttca atatgataag tttaatttaa
     4801 agtattattt tccaaaaaat aactttatca aaatagaaac tcaaagtaga tataagcctc
     4861 tttttcgcta ttaaaatagt aaaaatatat ttgacttaat ataaaaaaga gtgtctcatt
     4921 aactaataaa gtttattttg agacacccct cataaaacaa attatactac aatagatttt
     4981 tactaattct acaagttata tatttaaatt atattattca aattaaacta taattctaaa
     5041 tttcatttac tattaattcg cccattgctc ttgttcctac aacatttccc acaccattat
     5101 agatatcaat agttctataa cctttattga gtacactttg tacagcatct tcaatacact
     5161 tagcttcttc ttctaagtta aaactatgtc ttaacatcat gcttacagat agaatagttg
     5221 caattggatt tacaatatct tttccagcta tatcaggcgc acttccatgt attggttcat
     5281 acataccaaa actatcttct ctaagtgatg ctgatggtaa catacctata gaacccgtaa
     5341 tcatagatgc ttcatcagat attatatctc caaatatatt attagtcact attacatcaa
     5401 attggctagg gtcttttaca acttgcatag cagcattatc aacatacata tgtgacagtt
     5461 ctacatcctc aaactcttta gctaagtctt ccattatact tctccaaagt cttgaactct
     5521 caagcacatt tgccttatct acacttataa gttttttatt tctatttctg gctatttcaa
     5581 aagctctctt accaattctt cttatttcat tttcgttata tatttctaca tcataagcat
     5641 tttcgatacc atcaatgatt tttcttccac gttctccaaa ataaatgccc cctgttaatt
     5701 ctcttacaac aacaaaatca atgcctttct caactatatc cgttctaagt ggtgaagctt
     5761 cttttatact ttcatacatt gtagctggtc ttaaatttgc aaataaaccc aatgactctc
     5821 ttaattttaa aagaccagac tctggtcttt tatctccctt acatttatcc cactttggtc
     5881 ctccaacagc accaagcaat acagcttcgt tttttcgaca agtttcaaca gttttattag
     5941 gtagaggttc tccaatttca tcaatcgcgc atcctccagc taatacatat tcacaatcga
     6001 atctatgatt aaatttacaa caaattttat ttagaacctt tataccttca tctataattt
     6061 ccggtccaac accatcacct tttatgactg ctatattaca attcatactc cactaccccc
     6121 tatttgcttt tattgagtta attaagcctt catttaatat aatattttgc ataaactcag
     6181 gaaatggttc tgctttatat tctttttctt ttgttatatt ttttatcaca cctgtagaaa
     6241 aatctacttc tatattatcc ccttcatcta tgttattggc agcttcttca cattcaagta
     6301 taggaagccc tatatttata gagtttctaa aaaatattct agcaaaagta gaagcaatca
     6361 cacaggatac tccactttct tttattacaa ttggtgcatg ttctcttgat gaaccacaac
     6421 caaagttttt agttgcaact ataatatctc ctttttttac cttagaaata aatttatcat
     6481 caatatcctc catacaatgc gttgctagtt ctttataatc agctatattt aaatatctag
     6541 ctggtattat tacatctgta tctatattgt caccgaattt aaaaacactt ccattggcaa
     6601 tcataaattt tacctccctt aaattatttc tgatggtttt gatatttttc cagttatagc
     6661 tgatgctgct gctacagctg ggcttgcaag atacacctct gaatcaacat gccccattct
     6721 tcctacgaaa ttcctatttg ttgttgaaat ggatttttct cctgctgcaa gtatacccat
     6781 atgtccccct agacatggac cacaagttgg tgtagaaact gctgctcctg cctctataaa
     6841 agtggtaata tacccttttt ctatagcttc aagatatact ttttgagttc caggaaatat
     6901 cataactcta actccatctg ctactttttt gcctttcatt atctcagcta ctacttcaag
     6961 gtctgatatt cttccatttg tacaagaacc tattacaact tggtctatct ttatatcctt
     7021 atctatctca tctactgttc tagtattttc aggaagatga ggaaaggcta ctgtttcttt
     7081 tagttcggct aaatctattt cgtatacttc atcatagact gcatcttcat ctgcttcata
     7141 tatatttaca tcttttgtta tagttgaaca cttatgtgaa tttatatatt ccatagtctt
     7201 atcgtctact ggaaagattc cattttttgc tcctgcttct attgccatat tacaaatagt
     7261 aaatctatca tccatagata agtattctac tccatctcca caaaattcca tcgacttgta
     7321 aagtgctcca tcaacaccta tctcccctat tatatgaagt attatatctt taccacttat
     7381 ccatttattt ggtttattct tcaaaacaaa ttttattgct ccaggaacct taaaccaaca
     7441 ttttcctgta gccatacctg ctcccatatc agttgaacct acaccagtag aaaatgctcc
     7501 taatgctcca tatgtgcaag tatgagagtc agcacctata attacatctc cagcagttac
     7561 tatacctttt tcaggaagaa gaacatgctc tattcccata tctcctacat caaaaaaatt
     7621 tacaactcct tttgattttg cgaaacttct tgtaaattta cattgttctg cactctttat
     7681 atctttatta ggtgtaaagt ggtctaaaac catcactact ttagtcttat cataaacatc
     7741 ttcaattcct aatttttcaa attctctaat ggctactggt gatgttatat cattacctaa
     7801 aactacatct aaatctgctt cgattaattg ccctttctta acttcattta atttagcatg
     7861 tttggctaat attttctgcg tcatagtcat ccccattttt tatttcctcc tcaatataac
     7921 ttttatttat tgcattcata agtgcattaa tagctgctgt atttatgttt tccgatatac
     7981 ttacaccaaa atagacttca ttattgtgct ctattcctac ataagctacc cctcttgaat
     8041 gtgacccttc ctctaatgca tgttcccagt aatatctaaa tttataatct ttcatgccac
     8101 attgctttag tgcattatta aatgaatcta caggtccatt tcctatacca acaatccttt
     8161 gttcatttcc catataactt attcttgcag tcatctcaat catgttagta tcattagaat
     8221 catcattttc atagtttaat tcatccattg attttatttt atacttctta actttataag
     8281 ggctctcaac ttcaatatat tctttcttaa ataaattaaa tattgcttca ctactaagtt
     8341 cttccccaat tctatcagat tccattttga ctacatttcc aaaatcagaa tgcatattct
     8401 taggtatcat aaatccataa tctgtttcca ttatataaac agctcctcct tttccagatt
     8461 ggctatttat ccttataatt tctttgtatt ctcttccaat atcatgaggg tctattggta
     8521 aatatggaac ttcccagtaa tcattatctc tgtttttcat tgctatcatg ccttttctaa
     8581 tagcatcttg atgtgaacct gaaaaagcac aatgtacaag attacctgca tatggatgtc
     8641 tatcatgtac cataagtttt gtacagtctt catatatacc aattatctta tctatattgc
     8701 taaaatctag ctctgggtct attccttgtg tataaagatt aagtcccaca tttactatat
     8761 ccatatttcc agttctttca ccatttccaa atagtgttcc ttcaagtcta tcggcaccag
     8821 ccaataatcc aagttcactt gcagccgtac aagttcctct atcattgtga gtatgcaaac
     8881 ttagtataat agaatcccta caacttatat ttttacaaaa ccattctatt tggtctgcat
     8941 atacgtttgg tgttgccatt tccactgttg atggaagatt tattattact tttttttgag
     9001 gagttggttt ccaaacatct atcactgcct cacatatttc aagtgcataa tccatctctg
     9061 ttcctgtaaa actctctggt gaatattcaa aagtaaattc tgtttctgga tattttttta
     9121 cttcttcatt aaataatttt gctccttcaa ctgctatatc tattatttct tgtttactca
     9181 tattaaaaac cacatctctt tgaagaacag atgtagagtt atataaatgt ataattgctt
     9241 ttttacatcc ctttattgat tcaaatgttt tttctataag atgagcccta gattgtgtaa
     9301 gtacttgtat agttacatca tctggaatca tattctcatc tattaatttt cttaaaaatg
     9361 tatactctgt atttgatgct gatggaaatc ctacctctat ttctttaaat cctgtatcaa
     9421 taagcatttt gaacattctg actttttcat ttacactcat aggcgttggc agtgactgat
     9481 ttccgtctct taaatcgaca ctacaccaaa ttggagcctt aaatatttca ttatctggcc
     9541 atttacgatt tactatttgc attttatcat attttttata ctttccacac ttcatgttat
     9601 ttcccccttt ttctgttttt tgtattcagt ataccttata tcgacgcaat cctgcacact
     9661 tcataaggat aaatgtcaat tttatcatta gaataaaaaa aacctcatct ctaataaaat
     9721 tagagacgag gttttgctcg cggtaccact ctatttagct ttctaaaaag ctcccttagt
     9781 aatagccaat acaataatta taatgactat atttcctata acgtggaatt actccgatta
     9841 ttctaagatt taaatcttag aaaacagctc ctagacaagt tcagaactat caactactaa
     9901 atcacaccat cctttagctc tctgaaagtt tcattgttct tactacttct attcatcact
     9961 tttttaatca tttaaatttt ctaaatattt tgatttaata gttattatat acacattaaa
    10021 atgtattgtc aacaaaaaaa ataattatct caatttttta tttttgataa gcaattctat
    10081 aaaacatgct aactattgaa aacagtatga tattatgcct taaacttttt catcttttca
    10141 tctatgatat tcaataattt tttttcatct tccaaactca atgcccttaa tctaatttta
    10201 taattagatt cgtcagtgta tatatttaat atatttttta ctacttctat tttttctatt
    10261 atcttataat taaacttttg actttgttta gattttatac tgaatataca ttgattattt
    10321 attaatattg aatgattatc gagagtaata tatacttttc cctcatattt atttgaaaaa
    10381 tcacgacctt gtttaaatag aaaaactgct gttattatac ataaaatata taatattgtc
    10441 gttgaatata taaaaattgt agctaaaatt ataagtgcta aaaccatata tatagtcatt
    10501 ccttttttaa aataaccatt gtcataataa ttcatataga taaacttatt tttactcaaa
    10561 ttttttcact cccaagattc taaaaattta tatcaaaaaa ttctataatt tcatcttcat
    10621 gataatttat gactaattca tctggaaaat ctactgcttc taaaactttt tctgcatttt
    10681 caaattctcc tatagaataa catatatgag agtcagtacc aagaattact cttgtaccat
    10741 atgttttaca caatgtcaac atatgactta cattttccca agtacccgtt ctatgagagt
    10801 ttgaacttaa tgatgaatta tttatttcta aaaggatatt tttatcttta gcttttttta
    10861 ctataggttc ataatctaaa ggatacctac tgtcatctgg atgtccaatt atttttacct
    10921 taggtttatc cataactttt aaaatagcat ttgtattttc ttcttttgta ccagaagcta
    10981 tacaaggtct atgcaaactt gcgattatat aatccaaatg ttgcaacata tcttcttgaa
    11041 catctaaatt accactataa tccattatat ttccttctat tcccctaaga atctttacac
    11101 cttgcacttc acgtggaagc aaatgcaaat tataaaaata gaatggatgt ggtcctcctg
    11161 gcatattagg tccgtggtct gatattccta agtattttat attcttctta ctcgcctctt
    11221 cgacattttc cttgaaagta ctatgtgcat gtccacttat tagagtgtga caatgtacat
    11281 ccataataga ctttttcatt aaatttcctc ctaatatttt acataaattc gtgaaaatag
    11341 ctaaagggct atttcaaaac taaagctgtc ataatagaca gtgtaacgtt ttaaaacagc
    11401 cccattttca attattttac acttctaaat ctttaaattt atctttaaat aattctccaa
    11461 tacttcctaa agattcctct acttctaggt attctgttat atcctcttct ggctctctag
    11521 ttgcttcttt tattgaaacc aacattcttt tagtctttgg tttaaaatca agaatcttaa
    11581 ctttaacctc atctccaata ttaacaacat tagtaacttt agccactcta gtatcactca
    11641 attcagatat tggtaaatac gcatctacac cttctttaat ttgaacaaaa gccccttttt
    11701 ctattattct aagaacttta gcattgacaa catcatcaat ttgtacttct tttgctatta
    11761 aatcccaagg gtcattattt atgtctttta atgccaaggc aattttttta gtctctttat
    11821 ttacatccaa cacataaact tctacttctt gtccctctga aacaacatct tcaacacttt
    11881 caactcttgt ccaagctaaa ttatttatat gtgctaatcc ttcaatccca ccaatatcca
    11941 caaatgcacc ataaggcatt atctttgtca ccttaccatc tcttttttgt ccaacttcaa
    12001 gagaattaaa taagtcttct ttagctgctt tgatacgagc tttttcttct tctctttctt
    12061 gcttaattct tgctctttca gcttcttttt ctgccttaat ttgagctctt ctttcttctc
    12121 tctctttatt tatacgctct tgtaatacat ctctatgaga tgctacaagt ctattttttc
    12181 taacatccaa ttcttttata taaacttcta agttaagacc aacaaattta gatgtatctg
    12241 taataaattt tgtatcaagt tgagaaattg gtataaaaaa tgtatatgta ttgtaattag
    12301 caaatacacc tttatctata ttcttttcaa catttacagt tattattcta tgttcatcat
    12361 aagccttttg taactcggca aaatcatttc ttttgtcaag ttgtaattta gataaagtta
    12421 ttgtaccatc tttttgagat acttttgtta ttacagcagt tatttcatca cctatgtggt
    12481 atatatcttc tatatattga tttttttcta tgttcaattc acttataggt attattccat
    12541 caaacccata gtctaatcct aattgtactt catcatttct cactgcagtt atttttccag
    12601 ttgtcaattc tccaactttc actttgctga atacttgttc ttgctggtca agtaattctt
    12661 gcattgttaa atcattttcc attataaaca tcctttcctc ttattgatta tcatatctgt
    12721 aaatattata ccattaatat tgcaaatact tacatttttc ttactataat ttttaaaata
    12781 aattcaactt catatattta tacattatag aaaatatctt attaaattaa aatacaaatt
    12841 ctaattttta tctaataaaa tattttcata aaaaatttat attgtatatc ttattctttt
    12901 attgctttag gttttgatag aaaacattta taaaatataa agaaagaaat tgctgttata
    12961 gtagcagctg ttatatctgc aactggctct gctaaaatta ctgcaaaaag tttttcatta
    13021 aagaatgttg ggagtataaa tattaaaggt attaaaagta caatctttct aagtagagct
    13081 aaaaccaaag atattgttgc ttttccaagt gctaaaaatg tctgttgaca agctatttga
    13141 atcccaaaca taaaagcacc agcaaaatat atttttatac tccaactagt catactaagt
    13201 aactgcggat tcttattaaa tatactaaca aaaaatgcag gaaatatcat taataaaagc
    13261 cataaaatag tagaatatgt aaaacatgac aataaacaca acttaaatgt cttttttact
    13321 ctatcaagtt gacctgaacc ataattataa cttattattg gttgtgctcc ttgtgtaacc
    13381 cccatattag gaagcataag aatttgcatt atactgctca ttatggccat tgaacctact
    13441 gctaaatctc ctccatacat ttgtaattta ctatttaagg ctataagtac taaactttct
    13501 gtagattgca ttataaatgg agagattccc aagccaagca ctggtaagat gatacttgct
    13561 tttggtatca tatacttctt ttttatttta agtatacttt tctttccaaa gagaaacata
    13621 agtacccaaa tagcagaaac gccttgtgca attatagtag ctaatgcagc tccttttaca
    13681 cccatattaa agccaaatat aaaaatcggg tcaagtatta tgtttattaa agcacctata
    13741 gcaactgtca tcattccagt tgtagcaaac ccttgggtat ttataaaagt attcataccc
    13801 attgaaatct gaacaaacac tgtacctatt aaataaatat ttaaatagtc cattgaatat
    13861 ctaattgtag attcacttgc tccaaacatc caaagtaaag gctcttttcc aatcttaaaa
    13921 cctatagtca aaagtattgc taaaatcacc agtacagaaa aactgttact cattattttc
    13981 tctgcctcat cattgttttg ctcacccatt tttatagcag ctaatggacc tcctcccata
    14041 ccgattaaat aactacatgc agttattata attattattg gaaaggccac tccaacacca
    14101 gccatagcaa cttctccatt ttccattcta ccaataaaaa tcctatcgac tatgttgtat
    14161 aaaacattta caatttgtgc aataatagca ggtgtagcaa gtttaaataa taatttaccc
    14221 acactttcac tgcctaagtt agtgtttgaa ttttccattt taaaacctcc tcaatccaat
    14281 aattaaaatg tatcactaaa attttattct atataaaaat ttcattttat cagcagacaa
    14341 atttagagta ctttccctac aagtaatact atactatatt tcttttgcca tagtaaacat
    14401 tttagaacta actgaattta aatactttat ctcatttttt atttattatt aaaaattttt
    14461 cacatgtact cataaaaaaa ctatccaagt atattactta gatagtttta tattatatgt
    14521 aaagaaagag ctgaaactat aacccctgat aacaaattgc caagaaatac tcccataaaa
    14581 gcatctttta ttctcatttt taatatggaa gctatagcag atgcagtcca tgttcctgta
    14641 gttggcagtg gtatacctac aaatagtatt ataccaatta tcgaaacact ttttaatttc
    14701 ttcattcttg agtttatttt tctatcaatt acatcagcaa tccctttaaa tagtttcttc
    14761 cctcttaaaa attgtaatac atgtctgaat gtcaatatca agggaatcga taccaatgta
    14821 gaacctatta cactaaatac ataaacccat ataggattta agcccattgc aatacctata
    14881 ggaatggctc ccctcaattc tgttacagga accatagata aaattaatat gtgtaaatat
    14941 cccaaactat tccctcctat tctaagtgac attaagttat gaatttattt gctctataac
    15001 ctcaccatcc tttttactaa ctaaaaatgc atttttagtc aatgaaagca ttggtaaatc
    15061 actcttagag tctgaatatg catatgaatt ttcataatca atctctatcc caagtttacc
    15121 taatacagcc tttattcttt ttactttttc aattccctta cagttttctc caatgaattg
    15181 atttttatat cttgaatttt cataaaaaaa ctccgtgcct ataaccttgt ctgcaagacc
    15241 ataatactta aaatatttca tatatgcata tggagatgca gttatcataa ttataacatt
    15301 atcttcttct ttatttttgt aaatgacctt tttcatagat tcgttaattt ttttcattat
    15361 gcaatcatca aaaaactttt ttaaatcttc ttcactaaaa tctactattg gataaaagat
    15421 tgcctctttt gccttcttca agggtatcat tctaattaaa tacataaata gaataaaaat
    15481 aatgtatggc aactttataa tagttttaaa ggttttattt tttaaagagt aaataaaaaa
    15541 atctatcatg ctatcagtat ttataacagt ataatctaca tcaagtaata atacactttt
    15601 tttcataagt atttccccat cctatcacta aaaatatcac taaaaaatca atattattaa
    15661 acatgtaatt atccataaga ttacgtttat ttttaaagca ttatctttta ggacaatatc
    15721 agtaggatta ttttcatttg tagtgttaat tatataatta tatctaagta caccataaac
    15781 tacaaatatt gttgtaaata tcatatgtgg cttttctgga ttacttgtag aatacaatga
    15841 ataacataca attgtagaac ttaatataac tatcatcatt tgatttagat tttctatgtc
    15901 ataatcttcc aatatttttc tatgttcaac tgcatcatct cttagagttt ctatttcttt
    15961 tttacgtttt ccaagagcta agtacagaga taagaaaaat gtacataaaa ttatccaatt
    16021 tgataaacta acacttatgg ctacacatcc tgcataaacc ctaagtataa aaccaagaga
    16081 tattgaaaac acatctaata gtattatatt ctttagttta agagaatata atatattgtt
    16141 tatcaaatag agactaagaa ttatagaaag attaaaacta acaactgttg ataaacagac
    16201 tgaaattaaa gctaatacta caaatagtat attagcactt tttttgctta ttcttccact
    16261 tgccactggt ctattacatt ttttaggatg ttttttatct ttatccatgt ctatagcatc
    16321 attcagtgca tatactgatg atgacattag gcaaaaacac acaaacgcaa taaacgtatt
    16381 taaaaataaa tttatattta gtatgttgtt tgaaaaaatt atagctgaaa atacaaagaa
    16441 attctttata tattgcttta ttctcattaa ctttatataa tctgaaattt tagtaagaag
    16501 ccttatactt gtattggtct gtttcataaa cttactaccc tttcaatatt attttttaaa
    16561 caggatatga ttttatccct atgtttaaaa tttctataaa tccattgaca ttactgatta
    16621 ctatagtaac caataacagc gatagaaata tattatacat attcttttca ttttttctaa
    16681 gcgctttcgt aaagtaagcc aataaaatta taactgcaaa actaaaattt atagccataa
    16741 tacttgaatt gactagatta tatcctacta taccatgtaa agttagattg aatataatta
    16801 ttcccataca tagcttagga actctttttt ctgaattttc aataactgat aaaacacaaa
    16861 aacataaagc taataatgta agaattactg gtattgtagc aacttctcca ttttgcaaaa
    16921 ataacccttt tttaatactt gctccaggaa aataaaaaac cgaatacaat aatctctcta
    16981 taatcattgc aatcttttcc aaaattggtt ctccacttat aaatttcgta tcatactgta
    17041 ttacatttcc aaggttcata aaactctcat aagacttcgt tgaaactaca caaatatatg
    17101 ccattaggat aaatgtaatt aaatgtttta acatttttcc tatttttaat ttaaactcaa
    17161 atatcatatt aaaaaaatac aaatatatat tactaatagt tattccaaat agaggaatag
    17221 ctgctaattc tactaaataa gaattttttc ctttcatctt atttgcaata actatgaaaa
    17281 atattaatga aaattggcta tatataaatc tctctacatt taaagtcata aataactgtg
    17341 gaaaagaaaa tatcattatc atagtaagta aaattaaagt taatctctgc atttttatct
    17401 ttttaatatg attaaagact aaagttattg acatagcact agttattatt tgtagacaaa
    17461 ttagtccaaa cccataggca ctattaaaat ctgttgtccc aggatttgct attgaagtac
    17521 aaaataggta tattggatat gcaaaaattg atataattgc tgaaaacaat atgtgcttac
    17581 tattgtcttg acttatagca aatacattta aattgaataa aacccctgta tctgtatcta
    17641 acaatacatc ataagtattg tttaaattat aaaatatagt agtcttagaa aaaaatatct
    17701 tagttattat taagtaagtt attacaacta atataaacaa aaacatctcg tttttatatt
    17761 ttaatatttt actcatcaat atatcaccat ccattcatta tataggattt gctgacacct
    17821 acaatttatt ccttatattt aatagccatc ttcataatgt tcttacttgt tttattgtaa
    17881 ttgaataact ctttatttac aaccacaata tttactttat tgatgttata atcagtcaag
    17941 tattgtttat ataacataga ttagtgttgt ataaaatgag aatttgtaag caatattaat
    18001 gtaaaatatt tgaaaaactt tatataaaaa tatacaatgt tgcttatgga attaaactat
    18061 aacaaattaa agcataattt aaggagacaa aattataatc tgtctcctta aatattaaaa
    18121 ctatatttta aaacattact aaatactata caaatttcaa atatagtata aaattaatta
    18181 gactttaaca ctattagctc catcttcttc ccatttttta atttctttta atctatctat
    18241 tataggtaaa tgctgagtac attcaacttc acattttcca caagatatac attctttagc
    18301 ttttgcctta ctattcattg tgtaattcca atgtcctaaa ccataaacta actttgtcat
    18361 ttcttcatca ctctttttaa acatctgctt ttcattataa aaaagcatat aggctggggt
    18421 attaatacct tttggacata ctttacaata accacaacct gtacatattt cgttcatatt
    18481 cttatttaat ctagtctcaa tatcatgtat atcctcatct gaataaattc tattttcgtc
    18541 tgcaatttta catgcatcat ctatatcttg ttttttatta aaccctatca aagatatact
    18601 tatttgtgaa attcctatgt tgaatcttaa agctgattct atagtacttt cgccatcttt
    18661 tgatagaaaa gaaagttctt tattatactt tggaatagtt ccaccactta atggattcat
    18721 tgccacaaca ccatatccat tatcaacagc atatttggca ccttttagcc tatatggaaa
    18781 gtttaatata tttattccca tagttacacc ttcaaactta ttttcactta gaatatctat
    18841 aacctcatct cctggttgat gagatgaaaa tactatatgg tctatcaatc cttcttcttt
    18901 acatttcaat aatccttcat attgacctcc aggtctcatt gctagttcgt aatgttccat
    18961 ctttctaata ttccaaacat gataaaaatt tattttagat acgcctaatc gttctattga
    19021 tttttttaca gcctctatag ctttttctga tgtatcacat gcttttggct tttctttagt
    19081 tgatacataa aaatcggtct taccttcctt tatcatttgt ctaaaggcta gtccaaatat
    19141 atcttcactt ctgtcatcac aataccctgg cgctgtatca aagtaattaa tacctttttc
    19201 atacgcatat ttgactaaat cagcattttc ttgattactt ttttctaaat caaaccttaa
    19261 tcctccatag ccaactactg aaaccatttt ccctgtcttt ccatattcaa cgtatctcat
    19321 tgtaaattcc tccttagata tattaagact taatttcttt atagaaaata ttataccata
    19381 aataattttt ataaattatt tatggtataa tatttttttt ataaattata tttttttata
    19441 acttgtattt tatagctaag ttaaaaacta taaaaaggtt caatatggac tattacttga
    19501 gcattttcat taatttcttc ttgtatttgt ttctcaattt tatgtgttaa atcatgagat
    19561 tgctctacgc ttataaatgg gtctaccatt acatgcatgt caatataaat agaacttttg
    19621 ctacctctac ttctgatatt gtgaacatcc cttacctcat taaattcaaa cacaatttct
    19681 tttatataat cctcatctac agccactcta tcgaccaaaa ttccaataga tggcctaaat
    19741 attccataag ccgaataaat tatgaatgca gaaataataa taggaactat agattctatt
    19801 attactggaa atcctaactt aacaccaact aaagtaacca atacacctag agacacaaat
    19861 atatcacttc ttgtatgcaa tgaatccgaa attaaaacat aactatttag tttagtccca
    19921 attctatatt catacatgca tacaaaaata tttataaaaa gtgtaataat taaagcaatt
    19981 aaactttcta tagttatagc aggtacaact ggattagcta ttcttagcac tgcactaaga
    20041 attatcttaa ttgctataac aaacaacata ccacttataa ataaactggt tataatttca
    20101 aactttttat gtccataagg atgattttta tcttttggtt tagatgcaaa gaaaatacct
    20161 ataagcccca ctatattaga tgctccatct gacaaagaat gaaatccgtc tgctgtcata
    20221 ctatagcttt ttatttgatt accaataatg atttttaata atgctactgc aaaattagca
    20281 aataaaatta tccacaatac ttgcttcact ttcttatagt tatccataac aaattccccc
    20341 tcccttcgat tcaataaaga aagctatcta tcaatatcaa tcacccagat aataaaatcg
    20401 tatataagca catttactat atttatattc aaaattggtt gtacttgttc attctatttg
    20461 aaacttaatt ataaataaaa atcgtaggta tggttttggt atacataaaa ataagagact
    20521 gtctcaaaat aaagataagc ttctttttta ttgttgaaat gataaaatat atttgatttc
    20581 atataaaaaa gagtgcctca tgaactaaaa agttcatttt gagacactcc cttaaatttt
    20641 tgatataaac tattaatttt ttatactaag ccttctttaa ctaagaatga atgagcaact
    20701 tcttctggtg atttaccaag ttcatccact tgatagttaa gttctctcat agtttcttca
    20761 tttatttttc ctgaaagcat attcataact ttttctaact caggatattt cttcaaagta
    20821 tcttctctta ctaatggtgc tgcataatat ggtacaaaga aatttttatc gtcctctaat
    20881 atcttaagat taaacttttt aataagacca tcagttaaaa atgcatctat aacctgagat
    20941 tcattattat ctaaagctgt atatcttaaa cttccattca ttgcttttac atctttgaat
    21001 tttaaaccat aatctctaga aagccctaca agaccatctt ctctattttc aaactccaaa
    21061 gttggtgaga atgtaaattc tttaccatat ttagtcaaat cagaaatagt atttattcca
    21121 tacttttcag cagtttcagg catcatagct aatgtgtaag tattattaaa tccaagaggg
    21181 tcaagtaaag ttaactgatt ttctttttcc atagtatctt ttacaacatt atatgcttca
    21241 tcagcatctt taatcggagc atgtttcatt acatttacca aaagtgtacc tgtatagtca
    21301 acatacatgt ctaactcacc agatttaatt gcattaaacg caacagatga accacctaga
    21361 tttaaattct tcttaacttt aagattcgta tttttttcta ctaattcagc ataaacatta
    21421 ccaagtataa gttgttctgt ataatcttta gaaccaatag ttattgtatc ttttttactt
    21481 gaaaaactag aactaaaaac aacgaacaac attgaaacaa caaccactac agatattact
    21541 ttaagtgcta tataattttt cttaggtgct tttggattta atccttttgg agtaactgca
    21601 acttcaattt tactaaataa ataatcaact aacagtgcaa ttatacatga tgggattgcc
    21661 cctgctaaaa tcatattatt atttacagtt tgaacccctg aaaatactaa atatcctaaa
    21721 ccaccagcac ctataaatgc tgcaagagtc atcaaaccaa cagctgtaac tgcagatatt
    21781 ctaactccac ccattattat aggaagtgct aaagggaatt gtattttaaa taatgtctga
    21841 tttcttgtaa gaccaatacc tttagctgat tctaatacta ctgggtcaat acttgttata
    21901 cctatatacg tattttttac aattggtagt aatgaataaa ccactaccat aaatatggct
    21961 ggtttacttc ctatgccaag tataggtaca agaagaccca aaagtgccat agacggaact
    22021 gcttggacta agtttacaaa tccaagtaca aactttctaa gagatgagat tcttgaaata
    22081 attattccaa gaggaacacc aactattata gctattaaaa tagatgtaac agttagactc
    22141 atatgttgta ttaaaagctc tataatctta tctttttgta atagtataaa gttaaaaaaa
    22201 ttagccaaga acactcacct ccatttctaa gaattgttca cttaaaacag aaagtaaact
    22261 acttctagta ataagcccta ccagtttatt ttcatcagaa ataaccggaa tatatccaac
    22321 cgaattacga ttcattacat ttagtatttc tactaaatta tcaccttcat ttacatgcaa
    22381 aggctcactc gacataatat cagcaagtaa tattgactta tcatcaatat ctttcatatc
    22441 ttttacagta acaatacctt ttaatgtttt tgctctatct ataattagta agctatcaac
    22501 cttactcgtt ctcataattt ctattccttg agttacagtt ctagtggaat taacagcaat
    22561 aggatttttt atcataatat ctcttgcttt tatatattct ggattatccc aaactctatc
    22621 ttctccgata aaatctttta caaagtcatt tgcaggcttt ctaagtatat tttcgggagt
    22681 atcatattgt gctattcttc catccttcat aatacaaatt ttatcagcta tctttaaagc
    22741 ctcatccata tcatgcgtta caaatattat agtttttttc aattcatctt gaagagaaaa
    22801 taattgttct tgtaaagatg ttctcgttat tgggtctaaa gcactaaaag gctcatccat
    22861 caatattatt tcagcatcag tagcaatggc tcttgcaaca ccaattcttt gttgctgtcc
    22921 accactaagt tctgaaggat acttattcaa aaattcatca ctatcaagtc ctaccatctc
    22981 aagtagttgc aacgttcttt tttcaatttc ttcaacggat ttttcctttt ttaggcgtgg
    23041 aattagctct atattttctt ttattgtaag atgagggaat aggcctgtgt tctgtataac
    23101 atatcctatt tttcttctaa gctctatttc attttcctga gaaattggtt tgccattaat
    23161 atatatctca ccagatgtag gttttattaa tttgtttata agcttcaaag tagtagtctt
    23221 tccacaacca cttgaaccaa tcaaaactac caatgtacct gtttctacaa ctagagaaat
    23281 atcatctaat ataacattat ttcctatttt ttttgttaca tttcttatct ctatcataat
    23341 ttatcatccc ctttttcgaa caagcaacct tctccaatat tataagttgt ttttataatt
    23401 atatcatact attttattta tgtaaacaaa gtacgatttt taggtcacta tttgtctgaa
    23461 tattgctaca aatataaagt atttatatat agtatataat gtcaaaaaac aaaaagtata
    23521 aaaatattca taaaataaca ctagcctcaa ttatatagta ttaaagctag tgttatttca
    23581 tttaaacaaa actcacattt gaatactatc catgtattca aataatgtaa tatctttata
    23641 agtttctttt ttatcactta agtttgatat tgtaactccc aatagcctaa tttgttttcc
    23701 attaacctca acatttctca acaaattatc tacaccactt cttatatcat tatattcgtc
    23761 aatatagtgt tctaaactaa ggcttctagt tatctttgta aagtcctcat atttaatttt
    23821 taatgttaat gtttttccaa acttctcaga gctttttaat ctatgacata cttcttcaca
    23881 aagttcatca agaatgttgc gtgtttcttc ttcatcaata tccaaattat gacttaatgt
    23941 agtctcagcc ccaacagatt ttctaaccct atttggttcc actggtctat cgtctattcc
    24001 tctagcaaat ttatataatt cataacctct ttttttgaat atattttcaa gttcaaataa
    24061 atttaaacac cttaaatcat atccagtttt tatacctaaa tttttaagag tatttgaagt
    24121 aacttttcca acaccaaaaa atttattcac aggtaattta tctaaaaagt cctgggcatt
    24181 ttcttcggtt attacagtta acccatttgg ctttcttaag tctgatgcaa tcttagcaag
    24241 aaacttattg tatgacacac cagctgaaga agtaagacca acttctctaa atatatcttt
    24301 ttttatttgc tttgctatct caattgatga atcaatattt tttttatttt ttgttacatc
    24361 taagtaagct tcatctaaag ataatggttc aactaaatcc gtgtatctat aaaatatatc
    24421 tcttatttgc tctgacacac tcttataaac atcaaatcta ggtcttacaa aaactgcata
    24481 tggacaccta ttgtaagcta cagctgatgg catagctgaa tggataccaa attttctagc
    24541 ttcataagaa cacgttgcaa ccacacctcg gctttgtgga tttccaccga caataacagg
    24601 ttttcctttt aattttttat tatctctttg ttctatagat gcataaaaag cgtccatatc
    24661 tatatgaatt atttttctat aatgtttcat tattatcacc ttttaaagta taaatagatt
    24721 aattttattt atattacttt ttaattatac caaacttatg tttctttttg gtattttttc
    24781 attattttct ttatatattc atattttcca taaataaaac catctataat ccattaactt
    24841 caatataatt tataaaaaat ccttaaaaac acttgcaaaa actatataaa agctttacaa
    24901 taggtattcc aaggaactaa atttaaaatt ccttatggat aacagtatat atatttaatt
    24961 tatgggatgt tttaaaaaca aaagactgtc ttatacaaga cagcctactg attttattat
    25021 aattgtaatg gactgctcaa actattactt taaaacagcc catatttttt tatataattt
    25081 taactatagt aaagattttg tgaaggatat tctgggtcac aagttacatc tataccaagc
    25141 tttctaaatg tttgttcatc atctctattt aatatagtag tagaatgagc ttgacaccct
    25201 tttaataatg ctaacttttc catagcaaac tgtgcagttg gattagttac agcacaaata
    25261 ctaagtgcag ttaacacctc ttggcaacta agtgaaacat ttctactagc taaagtcttt
    25321 gtttttaagt ttatgatagg ttctaatatt acaggtgata ttaagtgcat atcatcagat
    25381 atattggcta aatgtttaat ggcatttaat actactgctg ctgttccatt cattaaatca
    25441 gaacccttac cagttaatat tgtaccatct tctaattcta atgcaactac aggacaagta
    25501 tcattcttgt cggcactttc ttttaattta ttactgtaat ttctagcagg taatacaaca
    25561 tttctatctt ctggctttaa gttaagctct tccataatca ttttcattct atcataagcg
    25621 cctttatcaa cttgtccctt tttatactca caggcagttt taaagtatct tcttattatt
    25681 tcttctatag aagcttttct tattacttca tcatctatta ttccaaagcc aactctatta
    25741 acacccatat cagttggaga ttggaaaatt gattcttttc cagttatctt ttctattatt
    25801 tttttaagca ctggaaataa ttccaaatct ctattgtagt ttactgacat ttcaccatac
    25861 gtttcaaggt ggaatgaatc tatcatattc acatctttta aatcaactgt agctgcttca
    25921 taagctatat tcaaaggatg ttttacaggt acattccaaa ctgggaatgt ctcaaactta
    25981 gaatatccaa ctacattacc tcttttattt tcatgataca actgacttag acaagtacca
    26041 agttttccac tattaggtcc tggtgctgtg actactacta ttggctttgt agtttctata
    26101 tattcatttg ctccatatcc ctcatcacta actatagtct caacatctga cggatatccc
    26161 tttgttggat aatgcttata aactttaatt cctctacgtt ctaatttatt tataaataca
    26221 gttgtagcag gttgtccttc aaatctagta attactacac tatttacatc tagttcataa
    26281 cctcttaaat catctattaa tcttaaaact tccatatcat aagtgatacc aaagtctcct
    26341 cttattttgt ttctttctat atctcctgca tagacacaaa ttacaacttc aactttttct
    26401 ttcatatgtt gtaatacttt tatctttgca ttttcatcaa atcctggaag tactcttttt
    26461 gcatgaaggt ctcccatcaa ttttcctcca aactctaaat aaagtttgtc aaaattattt
    26521 actctttcta agatgtattt agactgctct tctaaatatt ttttgtggtc aaatcctact
    26581 ttcatcttaa cacctcacta aattaaattt cttgttgata acagtatatt tatatatatt
    26641 tttttagtaa aacatcttat aaaaaaatgt taatactttt tcactcaaag taatattata
    26701 caattaagat taattttttt caagatagtt ttatggtaaa taagatatac ctaatataac
    26761 taataaaata agaatattat atttttatat ataagtataa tattctcacc ttaacattaa
    26821 tttatttcaa tattttcata tatcttttat tctaaattca atacttttct aatatcttct
    26881 ataccttgat aaacttcttg tttagaaaaa ttcatagctt ctaattcttc atcagtcttt
    26941 tccataagca tagtataaaa ttctattgct atatactgca tattttcact agttacagtc
    27001 ttagctttat caaataaaat ttcttctgct tcgtttacat ttccctgaaa aactaatctt
    27061 tttaaagtta taagtataac ttcttcttct gtattataca ctaaatcttt ttcttcatat
    27121 tcactgtatt tttttcccaa taaaagtctt gcaaccataa gttttatctc attgaaaatc
    27181 ttatccacta tagccatttt tacatctcct ataaataaat tttattttct ttttaattat
    27241 atcagacttt attgtaaaaa ttattatatg taaatgaaat aattcaaaaa taaattctaa
    27301 caataaaaaa aagaaggtag cgggggattt ccgactacct tcaaacacta gattgtgatt
    27361 ggtttggtat tttatttata cccaccataa gctttattaa atcatctaaa ttgatttttt
    27421 tagcatccac atcctccatc aaaaacgtca ccacattcac aaagtattaa taataatatt
    27481 aagaaaggta tccatgcaca taagtccatt tcagcccaac aatcttggaa tgctaagaat
    27541 aagaagaata atattattat ccaccaagca catccaccaa atccgccttc accaaaaaat
    27601 ctatccaaca taatatgtta cctcctagtc attttgtatg tggagtttca gctcctaaaa
    27661 tatactatgt ttaaggggta atatttgcta atgatttttt taaatttttt ttagatattt
    27721 taaaaaaaat tattgattca cactcaatgt cttaccatca ctattgataa ctacctctcc
    27781 actagaagtc aaaaatgttt ttatattcaa tctttccaat atttttaaaa caccttcctc
    27841 tggttctttt ttctctgaac atgtaataac agcatattgg ggtgaagtag actctaaaaa
    27901 tgtttcagtt aatttgtcat atcttccatg atgaggcatt ttaacaaaat catattttaa
    27961 agtatttcca tttataaact ctgacaatct ttcttcctct gcatctcctg caaataaaaa
    28021 cttatgtgct ccatagctta tattagtgat tattgaataa tcatttgaac tctcgtactt
    28081 gctttttgaa gccggatgta tgtttatttc tgcactattg attacaatat tcatattatc
    28141 ttttagtagc actggttcta tatcagcttt tttaagtgag tcaatatatt catcatattg
    28201 cttactatct ttcttataat ttgcttgtat aatattcttt actttaacac tagataacac
    28261 actatctact ccacctatat ggtccttatc taaatgggtt aaactgaacc tcc
//
LOCUS       DAEQJM010000048        28144 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.048, whole genome shotgun sequence.
ACCESSION   DAEQJM010000048 DAEQJM010000000
VERSION     DAEQJM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28144
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.048"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..186
                     /locus_tag="KRQ43_002548"
     CDS             <1..186
                     /locus_tag="KRQ43_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH2742898.1"
                     /translation="KTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSL
                     LGAPIVVMLLVKRKDRA"
     gene            189..1385
                     /locus_tag="KRQ43_002549"
     CDS             189..1385
                     /locus_tag="KRQ43_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742899.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(1505..2230)
                     /locus_tag="KRQ43_002550"
     CDS             complement(1505..2230)
                     /locus_tag="KRQ43_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH2742900.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGANFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTPFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            2708..4807
                     /gene="nrdE"
                     /locus_tag="KRQ43_002551"
     CDS             2708..4807
                     /gene="nrdE"
                     /locus_tag="KRQ43_002551"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBH2742901.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYLKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            4820..5791
                     /gene="nrdF"
                     /locus_tag="KRQ43_002552"
     CDS             4820..5791
                     /gene="nrdF"
                     /locus_tag="KRQ43_002552"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBH2742902.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKKMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            5867..6493
                     /locus_tag="KRQ43_002553"
     CDS             5867..6493
                     /locus_tag="KRQ43_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH2742903.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIIEIPEQKFIMLKGSGDPNSKEFI
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
     gene            6888..7517
                     /locus_tag="KRQ43_002554"
     CDS             6888..7517
                     /locus_tag="KRQ43_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742904.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINNFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            7518..8300
                     /locus_tag="KRQ43_002555"
     CDS             7518..8300
                     /locus_tag="KRQ43_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742905.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAINTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            8293..9171
                     /locus_tag="KRQ43_002556"
     CDS             8293..9171
                     /locus_tag="KRQ43_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742906.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRIIGKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIKIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDGYNRDLTSEYYI
                     KLKKDILMTMKSNKDI"
     gene            9204..10163
                     /locus_tag="KRQ43_002557"
     CDS             9204..10163
                     /locus_tag="KRQ43_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH2742907.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDVALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            10477..11169
                     /locus_tag="KRQ43_002558"
     CDS             10477..11169
                     /locus_tag="KRQ43_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2742908.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            11179..12183
                     /locus_tag="KRQ43_002559"
     CDS             11179..12183
                     /locus_tag="KRQ43_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2742909.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGIHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKM
                     "
     gene            12431..13282
                     /locus_tag="KRQ43_002560"
     CDS             12431..13282
                     /locus_tag="KRQ43_002560"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH2742910.1"
                     /translation="MSLDVIFILKSVIIAIVEGFTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            13386..14132
                     /locus_tag="KRQ43_002561"
     CDS             13386..14132
                     /locus_tag="KRQ43_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2742911.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            14132..16048
                     /locus_tag="KRQ43_002562"
     CDS             14132..16048
                     /locus_tag="KRQ43_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2742912.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTYFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLIYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            16327..17244
                     /locus_tag="KRQ43_002563"
     CDS             16327..17244
                     /locus_tag="KRQ43_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH2742913.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYKSEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSIIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILSEIEKMKKIY"
     gene            17322..18059
                     /gene="cas6"
                     /locus_tag="KRQ43_002564"
     CDS             17322..18059
                     /gene="cas6"
                     /locus_tag="KRQ43_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH2742914.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KAYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKIVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            18065..19942
                     /gene="cas8a1"
                     /locus_tag="KRQ43_002565"
     CDS             18065..19942
                     /gene="cas8a1"
                     /locus_tag="KRQ43_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HBH2742915.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNLIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQIMFNDYLRQIIYFGELADLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKEYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTSINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFTDKYANKKIQSIYDYKLK
                     SNVLDLLLKNRDLKHLTNNILRNKVKNDMESNNKSNISGIDCFRVVQLRALINSYKKG
                     VYKMDSKNLEKNDEKLRIIYYLGCDIHDYFVNKNSKNKIDGVSYKLLNSVKVGNKSDF
                     MDTIIRVFMSAEKQIPAFILDIEIEKDLDFESIGHAFISGLISGKYEGKDKLPNEKEE
                     K"
     gene            19944..20858
                     /gene="cas7i"
                     /locus_tag="KRQ43_002566"
     CDS             19944..20858
                     /gene="cas7i"
                     /locus_tag="KRQ43_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBH2742916.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            20860..21561
                     /gene="cas5b"
                     /locus_tag="KRQ43_002567"
     CDS             20860..21561
                     /gene="cas5b"
                     /locus_tag="KRQ43_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HBH2742917.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            21572..23893
                     /locus_tag="KRQ43_002568"
     CDS             21572..23893
                     /locus_tag="KRQ43_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH2742918.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQREFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIIGVGEANDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLADLTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIHENKHTKQIFGKGVLISNEIDQFI"
     gene            23908..24459
                     /gene="cas4"
                     /locus_tag="KRQ43_002569"
     CDS             23908..24459
                     /gene="cas4"
                     /locus_tag="KRQ43_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HBH2742919.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEMLIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKEKIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            24462..25442
                     /gene="cas1b"
                     /locus_tag="KRQ43_002570"
     CDS             24462..25442
                     /gene="cas1b"
                     /locus_tag="KRQ43_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HBH2742920.1"
                     /translation="MYKDYYIISNGNIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNTLMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIVDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            25445..25711
                     /gene="cas2"
                     /locus_tag="KRQ43_002571"
     CDS             25445..25711
                     /gene="cas2"
                     /locus_tag="KRQ43_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HBH2742921.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITDGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   25895..27512
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=25895..25923
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            27702..28130
                     /locus_tag="KRQ43_002572"
     CDS             27702..28130
                     /locus_tag="KRQ43_002572"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBH2742922.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIEPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
BASE COUNT        11409 a         2641 c         4820 g         9274 t
ORIGIN      
        1 aaaacatcag ataatagagt tttgatacca gtagtaatat ttttaggcag tatagttaca
       61 gctctttgtg atttaatatc aagagtaatt ttatcaccag tagaattacc aataagcacg
      121 ataacatctt tattaggagc tccaattgta gtaatgttat tggtgaaaag gaaggatagg
      181 gcttagacat gttgaaaact aataatttaa gtgtaggata caataacaag gtagttataa
      241 gtaatataaa tgtagaagta aaaaatggag aaatactatg tcttttggga agtaatggag
      301 ctggaaaaac taccctatta aggtccttat ctaaacttat atcaccaata aaaggtgaaa
      361 tatatttgaa tggtgtaaac ataaattgta tatcaagaaa agcattatca aaaaaaatgg
      421 ctttagtact tacaaataga ttattaggtg atttaatgac tgtacaagat atagtcaata
      481 taggaaggta tccatataca ggattttttg ggagtctatc taagaaagat ttaataatgg
      541 tagatgaagc attggagtct gtagatgcct tacatttaaa gaaaagatat tttgatgaac
      601 taagtgatgg agaaaaacaa aaggtgttgg ttgcaagagc tcttgttcaa gaaccagaaa
      661 taattatatt agatgagcct acaactcact tggatataaa acatagattg gagctcataa
      721 acatactgaa aaaattaagt aaagaaaagt caatatcagt aatactttca ttgcatgaaa
      781 tagacatagc attaaaaagt tgtgataaag ttgctcttat aaaaaataat aaagtcatag
      841 cttatggtca gcctgaagat gtagtagatg aggatattat aaattcgctt tatgaattgg
      901 atgataaaaa ctttaatagt cttttaggtt cagtagaaat tagtaataaa tctaaaaatg
      961 aagtttttat aattggtggt gggggtaaag caacaccaat ttatagagct tttactaaaa
     1021 aaggtatagg tctgtattct ggaataatac atgaaaatga tattgattat gaaattggta
     1081 gaactatggg gataaagatg tttacagaaa atccatttga gccgataagt gatgagagtt
     1141 tcgatttggc tattagaaat ttaaatgatt ccaagattat aatagataca ggatttagtg
     1201 taggagagac aaataagagg aatatagata ttataaaaga ggctttaaaa ctggataaaa
     1261 aagtttattc ttttagaaat agagatgaga gtaagaagta ttatgacagt ttggatagta
     1321 agatagaaca tatagataaa gtttctcaaa taatcaatag tgcagatata aataatttat
     1381 tataatttat gaaataaaat gtacttatgt gctatagaaa aaagagtata gattataatt
     1441 tttttgaaat tacaatctat actcttttgt tattttgttt atatatttat aaaactttag
     1501 cattttatag ataaccaata gcttcctctc tagttaaaaa aaagtgaatc cctgtagtcg
     1561 attctttcca tctattttca ttaaaatctt cagctacaat cgtttctcct actctatata
     1621 taaaattttc atcagcatat gcacgagcac ttttaaaaga ttctttacca tctatactag
     1681 taattgacag tacttttgcc ttatcacatc tacaagcatt tgatgtagca gacactcttt
     1741 ttgcgtcgct gggtattaat aattgtacca ttctgaaatt aaaacatttt ttatagccta
     1801 taaatgctcc tgtttcagga caatacaatt taaaaaaagg ggtactttca tctgatatta
     1861 ctccatttaa agtagcatgt tctaaattgg aattttctaa attagctcct ctaatatctg
     1921 agttagataa gtcacaaaat ctaaaatttg caccacttaa gtctgcattt tttaatatag
     1981 aattttttaa tgaacaatcc gaaagataag aattattaaa aatagagttt tctaaatctg
     2041 ctttttctaa atttaaattg ataaggtcag accacgaaaa gtcaatatta cttaagcagt
     2101 atcctcttaa gtccatattt tctaatctta attcttttaa atctgccttt tctccagcat
     2161 tattgttttt aagccataaa taatgtttct caagtgtttt ttctaattct tgtttagaaa
     2221 tagttttcat taaaatcacc ttcataaatt tatttttata tatgtagtag caaaatagtc
     2281 atatatttaa ttatataaca ataaataaaa aacttctaaa taatatataa aatatcatct
     2341 tgaaagtact tttttcaata tatcagaata tatttttaag ctatttagag ataatttaaa
     2401 tttttaaaca ggacataata agcttgtatt tttttatatt tgagttgata aaaatttctt
     2461 taaataaaaa taatgtcaat tataaagtaa taaaagttta gatataaaaa aatttgtgta
     2521 tatactatat gtagtatata atagataaag cactgactat atgtagtgct tttgtttttg
     2581 aaaaatactt attgcatttc tataattata gattaatttt gggatttcaa ctgataagta
     2641 ccaaaagaaa taataagcaa attaagtgaa attatggcac aagattatgt taaaaggacg
     2701 gtaaataatg aattggatag agcttaacaa tcaagtgata attaaaaatg aacaaggtaa
     2761 gtaccaattg gaaaaggata aggaagcctt aagtagttac atagaagaat ttatacaacc
     2821 aaagttgaga aaatttaata acctagaaga aagattgaag tatttaatag atgaaggtta
     2881 ttatttaaaa gaagtaataa atcagtatag catagatgtt attaaaaata tatatgatat
     2941 gattgataaa cataagtttg aatttcaatc atatatgagt gcaaataagt tttatcaaaa
     3001 ttatgcatta aagagcaatg atggaaagga aatattagaa acatataatg ataaagtgtt
     3061 aattgtagct ttgacactag gaaatggcga taaagattta gctttaaact tggcagataa
     3121 aatagtaaaa caagaatttc aaccagctac acctactttt ttaaatgctg gaagaaagag
     3181 ggctggagaa atggtatcat gttttttact atctgtagaa gatagtacag aaggtatatc
     3241 atatgctata tcttcatcaa atcacttatc aaagattggt ggaggagttg cactaaattt
     3301 atctaaactt agagcatctg gcgaatctat caaagatata gaaggtgcag ctggaggtgt
     3361 tgttggagta gctaaaatgt tagaacaatc atttagttac tttaatcaaa tgggagctag
     3421 acaaggttct ggtgcggtgt accttactgt attccatcct gattttgaat tgttgatgga
     3481 tactaaaaag ataaatgcag atgaaaaaat aagacttgct acattatcat taggagctat
     3541 aataccagat aaatttatgg agttggcaga aaaaaatgaa gtagcatatg cattttatcc
     3601 tcatactgtg tataagaaat atggagtttc tcttgatgag atagaaatgg atgagtggta
     3661 tgataaattg gttaatgata gtgatataag aaaaaaagaa ataaatccta ggcagatgtt
     3721 gacaaaaata gcacaaatgc aacaagaaag tggatatcca tatgtagtgt acatagatac
     3781 agctaataga gaacatacat taaaagatgt tggaattatt aaaatgtcta acttatgttg
     3841 tgagatattt caatatcaaa caccttcaga aatagagggg tatggaggaa aaaatgaatg
     3901 gggacaagat ataagttgta acctaggttc tttaaacata gccaatgtaa tggataataa
     3961 aactatagaa agtacagttg aaacagcaat aagagcactg tcatttgtag cagatagcac
     4021 agatataaaa ccagtgccaa cggtaagcaa tagtaacagc aagtctcatt ctataggatt
     4081 aggagctatg aatttacatg gatacttagt aagagaaaat attttatata cttcagatga
     4141 tgctatagat ttttctaatg tattttttgc aatggttaga tactattcaa ttaaagcttc
     4201 tatgaaaata gccatagaaa gaaatcaaac ttttgaagga tttgataaat cagaatatgt
     4261 taagggaaga aatagcaagg ttttatcaaa atactatgaa caatcttatc tacctaagtc
     4321 agaaaaggta agagcattat ttgaagggat ttatatacca acaaaagaag attggacaaa
     4381 attattggat gaagtaaaag aaaaagggat atataatgca tatttaatgg cagtagcacc
     4441 aactcaaagc attagttatg ttcaaaatgc tacatcaagt ataatgccaa ttactgagcc
     4501 agtagaagta agaacatatg gagactctac tacaatatat ccaatgccat ttttaacaaa
     4561 tgataatatg ttgtattatc aatcagcata caggatggat atgagaaagg tcatagattt
     4621 agtggcaaca gttcaaaacc atgttgacca aggtatatca acaacactgt ttgttacaga
     4681 tgaaaagaca actagagata tagctagaca ttacatatat gcctataaaa aaggtttgaa
     4741 aagtttatat tacacaagaa caaagatgac aagagatact catgagtgtc tagtgtgttc
     4801 agtataggga gagaaatata tgacatttaa tttacataaa atacataatg cagttaactg
     4861 gaatagagaa gaagatggat ttacacaagc tttttgggaa caaaatgtaa aacaattttg
     4921 gcttcctgaa gaaatatctg tttctaaaga cataaaggta tggaatgaac taagtaataa
     4981 agaaaaggaa ttatataaaa aagtattggg tggtttaaca ttactggata caaaacaggg
     5041 gaataatgga ataccatcta tgatgagttt aacagaaaac ctacaaagaa aagctgtctt
     5101 gtcttttatg gggactatgg aagaaataca tgcaaaaagt tattcttcta tatttatgac
     5161 tctactttct aatttagaaa tagatgaatt atttgaatgg atagaaacag aaccaacatt
     5221 acaaagaaag gctgatttag ttttagctca atacgaaaat actacaaatc aagagggatt
     5281 atacctatca atggttacaa gtgtattttt agagagtttc ttgttttatt caggattctt
     5341 ttatccattg tatctatctg gtcaaggaaa gatggtagct agtggagaaa taatatcgct
     5401 tattcttaga gatgagtctt tacatggtaa gtatatagga ttgctagcac aagaaatata
     5461 cgattcattt gataaaatgg ataagaagat gttagaagag aagatgtatt ctatacttta
     5521 tagccttatg gagaatgaga tagagtatac aaatgttata tacagagaaa gtgggcttga
     5581 aaaagaggtt gtgaactttt taaaatacaa tgcgaataga gctttagaaa atctagggtt
     5641 tgagaagcta tatactgtag atgctataaa tccaattgta ttaaatggtc ttagcactga
     5701 aaccaaaaca catgatttct tttcaactaa gggtaatgga taccaaaaag gagtgtatga
     5761 ggaattagag gatgaagatt ttataatata atttataatt atgacacact gttgtcactt
     5821 ttagcgtgat aatatcaatg tataaaatat atatggaggt atttttatga aatatgaatg
     5881 gagaaaaaga gataaagagt tatatttacc taaaaagaat cctgtaataa ttgaaatacc
     5941 agaacagaaa tttatcatgt taaaagggag tggagaccca aattctaaag aatttattga
     6001 agcaatagga gtactttatt ctttggcata tgcaataaaa accatgccta aaaaaggaat
     6061 tgtaccagaa gggtattttg actatacggt ttttccttta gaaggtatat gggataaggg
     6121 agaaaaaagt aaaggcttag atgtacttat taaagaagat ttaatttaca ctataatgat
     6181 acgtcagcca gattttgtta cacaagacct gttggataaa gctactgata tagtaaagaa
     6241 gaagaaacct cataatcttc ttgaaaaagt taggtttggg tctattaatg aagggctatg
     6301 tgttcaaatg cttcatatag gttcatatga taatgaacca gaaagttttg acattatgaa
     6361 cgaattttgc aaaaaaaata aacttataag aaaatcttac acacatcgtg aaatttatat
     6421 aagtgatgct agaaaagtat cgcctgaatc attgaagacg gttttacgtt ttgaagtaga
     6481 aagggaagta taaatatttt gaataattta taagagttat aaaaagtgaa gtctgttgag
     6541 acttcatttt ttgatgcaat tttaaaatta aatttgatgt ttcataatat tttaaaaact
     6601 ttctactttt attagtgtga ataactgttg ctattaaata ataatactaa ttatataagt
     6661 attattatat aatatttata gattattata taaatagatt attagtaaga tgtatgcatt
     6721 attaattaaa ataaattaca tatactattt aatatttcat ttaaaatatt aaaaaatgta
     6781 gataaaaatt gttttattaa ggaaaaatta atatattgac aaaatttaag tgctcattta
     6841 aactattaat tgataataat attcaatatt aaataatagg aggcgttatg aataaatatc
     6901 ttctaataaa tccagtggca gaaagaatgt atggagaaaa gtttcacctt attaaagcaa
     6961 atttgataaa aaaggggtac ataatagcag aatgtgaacc acagttagaa tatgtaaaaa
     7021 agcagtacaa agagtataca aaaaagactg aaaatacaat gttggattgt agatgtccag
     7081 aaagtataag tcttttaaaa agaaataatt tgataaataa ttttgaagta cctatgatag
     7141 aaccaatatt agtaaggact tgtagggttt tatacgataa atatataaaa agtaaagatg
     7201 atatgttggt agtaacctgt ccatgtacac aattaagaga ctttgcaagt gaaaagttta
     7261 aggataaggg taatgctatg ttttatacat ggaaagagtt tgctgaacaa gaaggtgtaa
     7321 aatcacttgg aaaaatagat gaatcaccaa ttccattagg atatttcaaa gatacttttg
     7381 aaaaagttct tgaagtatca agtgaagacg aaatattaag tgaaatacaa aaaataagaa
     7441 atggctttga agataagtat gacatagtag aaatgtttta ttgtaaagat ggttgtaata
     7501 atggagatgg tttgtaaatg gtcaataaat ttaataataa gtttttaagg ctagtaaaga
     7561 gtgttctgat attttttata attcttttat tatggaaaat tacaaattat cttggtattt
     7621 ggagtgatta tatattacca tcacccgaaa aggtatatag tacattttta aatatgataa
     7681 gtgatggttc aatatttatt aatgtatatg caagtatgaa aagagttttg ataggttttg
     7741 caataaatac tgctataggt gtgcctttag ggatattctt tggaatttat agtggagtat
     7801 acgaatactt taaatctcta ataaattttt taaggaatac acctcccctt gctttaatac
     7861 caatgcttat attatggttt ggtataggag aggaatcaaa aattataatt atagttttag
     7921 catccttttt cccaatcttt acaagcacat tgaaagggat taaaaattgt gactcaaaac
     7981 tgattgaagt gggtagagta tttgagtttt caaagcttca gataatattt aaaataataa
     8041 taccaaatgc cattcttgat attgctgttg ggttaaagtt agctcttgga tatagcttta
     8101 gagcaattat tggggcagaa cttgtagcag cttcatctgg tcttggatac ttgatatctg
     8161 atggaaaaga aatgtctaga acagatgttg ttattgtagg tataatcgta attggacttt
     8221 taggaataat tacagattac atattttcga ttattgtgaa gaaggtaagt aagggaaaga
     8281 tggtggaagc atatgaataa tttagtatgt gactctggat atataattag aaatttatat
     8341 aaaagttata aagttgacaa tgaagaacat gtagttctta gtgatatctc tttaaacata
     8401 gatagaaacc atataacagt aattttaggt gaaagtggtt gtggaaagac taccttgctt
     8461 agagcaattg catcacttga aggtataaat agtggtgaga ttaggtttat taatgataat
     8521 aaagagtata gacctaatgt tggttttgtt tttcaggaga gcagattaat gccttggtta
     8581 aacgtaagtg aaaatatagc ttttcataat caaagaaaaa atactatttt aaacaaggtg
     8641 cttagaaaat ttaaacacaa taaaagaatt attggtaaaa ttataaatga taattttaga
     8701 agcttagaaa caaatgataa tttgaacaaa tcaaataaat ataataggaa aagtaatatt
     8761 gatgtagaaa aatatcttaa gatgatgaac ttgcagaaat ttaaaaactc ttatccaaat
     8821 gaattgtcag gaggtatggc acagagagta agcatagcta gagctctttc tttcaatcca
     8881 gatatgttgc ttatggacga gcctttttcg gcattagatt attttacaag gattgatatg
     8941 caaaatgaag ttataaaaat acataagtca actaataaag gcgtaatatt tgtaactcat
     9001 gatattgatg aagcgttaaa gataggcaaa aaaatagttg ttttcacaga cgaaagaaaa
     9061 ataaaagaat ttaatataga agatggttat aatagagatt taacttcaga gtactatatt
     9121 aaattaaaaa aagatatttt aatgacaatg aaatcaaata aagacattta aagaaattaa
     9181 taatatttta aggagtagag taaatgaaat taaaaaagct attgataggt ataacgatat
     9241 taacacttgc aacagcatct ttagctggat gtgctaaaaa aaataatgga gaaaaacttt
     9301 cagaaataaa tttaacttat gtaaaatcac cattaaatgt tccttctata attcagaaac
     9361 aggatgattt atttggaaag gaatttaaaa aggataatat aaaagttaac tttcacgaaa
     9421 ttactacagg tccagagcaa acacaggctt tagctgctgg agaaatagac ttcttacatg
     9481 cactaggtgg tacgtcagct ttaatagctg catctaatgg agtagagtta aagatattaa
     9541 acacttatag caggtcacca aaaggattta tgattttgac taataataat tcaataaaat
     9601 cagcagcaga tttagtaggt aagaaggtgg caggtccaaa agggactata ttacatcagg
     9661 tattgatttc agcacttgat aaagaaggat taagtatgga tgatgtggaa tttgttaata
     9721 tgggtattcc agaagcatca gcagctcttt ctgatggtag cgtagatgtt gcattgattg
     9781 ctggtccagc agctcttaaa gctatgaagt caggtagtaa acttgtagca aatggtgaag
     9841 gtttagtaga tggtataata gtaactgctg ttagcacaga ctttgcagag aaacacccag
     9901 aaatagttga aagatttatg aaggttgaaa aggaaacttt agaatatgta aataataatt
     9961 ttgatgaagc tatggaaaaa gtagctaaag aagttgattt aagtcttgaa gaaactaaag
    10021 aattatatgc ttggtatgat tttagtttag atataacaga taaagatata tcttcgcttg
    10081 aagatacaca agacttctta ataaaaaata agttacaaga gaaaaaagtg aatataaaag
    10141 aattaatcta taatgctaag tagaaactat gctaaaataa tactaagtaa gaaatataat
    10201 aaaagtttaa gttaccttat taaggtaact ttttctattt tgaattagta atttcaattt
    10261 attttagaat gattagttga taataatgat taattaatca taaaaagata cttttttata
    10321 gagttttatt aagatgtcta ataatatggt tatacttatg aagtcagtaa ttgtgaagtt
    10381 aataatatga ttaaatttat atattgtaaa aagattataa tatattaaaa ttggactgtt
    10441 atatgatgag taaataggta tattaggagg aattatatga gttataaagt atatattgtg
    10501 gaagatgata tatcaataag tacattactt aaagattata ttgagaaata tggatttgaa
    10561 gtgattgttg aagagaactt tgatgatata atgattacat ttgaaagttt taagccacac
    10621 ttagttctat tagatgtaaa tttacctaaa tttgatggtt tctactggtg tagatgtatt
    10681 agacaacagt cgaatttacc tataattttt atatcagcta gagatggcaa tgtagaccaa
    10741 attagagctt tagaaagtgg agcagatgat tatataacaa aaccttttta ctatgatgta
    10801 gtaatggcaa aaataaagag tcatataaga agggtatatg gtgaatattc acctaaaata
    10861 gacgaaagaa tagtggagct agatggatta aagttttatc cagaaaggtt agaactagaa
    10921 ttaaatggtg aaaatctaat tataactaaa aaagaaggta tactgattga atgtcttatc
    10981 aagagatacc caaaagtagt aagtagagat tatcttttag aaaagatatg ggatgatatt
    11041 gagtttgtag aagaaaatac tttaaatgta aatgttagca ggataaggaa aagatttgag
    11101 gaattaggta tagataatgc tgttcagact gtccgagggt taggatataa attaaataag
    11161 aattggtaag gagaaagtat gaagttattt ttaaaagatt ataaaggtta tatttttata
    11221 tattatatag gcatagttat gacaattatt tactgtaatc ttatgaagtt tattagtttt
    11281 ggagagagtt tatatattct tttatttagt tcttttatat tgttatgttt tttaatatat
    11341 aagtattata aaaatagaga agtatataat ctgtttgaaa aaggaataca ttctttggag
    11401 gagtcatttt tgtatttagg aagctcattc ttggggagaa atatatcagt tattttaaaa
    11461 caacaacata aattgtatca atcaatgata caagagcata aaaagataca tagtgaacat
    11521 ttaactttca tcaaccaatg gattcatcag atgaaaacac caatatcagt tataagcctt
    11581 cagcttcaag attatgaggg agaagaagta actgaaaata taagaaaaga aatagataga
    11641 ttaaataaag ggttagatat ggctatgcat tttgcaaggg cagataattt tcagaaagac
    11701 tttatagttg aaaaagccaa attaaatgaa attgtatcta gtattgtaaa tgaagaaaaa
    11761 aggttattta taaaaagtgg aatgattcct aagattcaag tagacaaatt tacttatgtt
    11821 tatacagatg taaaatggat gaaatttata ataggtcaat taattacaaa tggagtgaaa
    11881 tattctaaag attatagtaa ctacctaact ataaaatctg aagaaaataa taaatatgta
    11941 attttaagta taatagatga aggaattgga attgtttcta aagatttaaa aagggtattt
    12001 gacccatttt ttacaggaga aaatggtcgt aagtttggag aatctacagg tatgggtctt
    12061 tatctagtaa aaaaggtatg tgatgattta ggtcataaag taagtataaa atcagaagta
    12121 ggaaaaggta cagaagtttc aatctacttt aataaagatg taaatagttt gataaagatg
    12181 taaattatct gttacaatag ggtttttagt taattgtact tttttattat acaatttatt
    12241 aaatgaaata ttcatagtta aataatcaaa atttaagaga gtttatttgc aaaccttaca
    12301 tagatgtaag gtttgtgtaa tgtttgcaga tagttaaatt ttctaatcta aattacaatt
    12361 aatataagaa ataacatgag agaaataaca taaaaaaaga aattttgtaa aaaaggaagg
    12421 atgtttattg atgagtttag atgttatttt tatattgaaa tcagtcataa tagctatagt
    12481 agaggggttt acagaattta ttccagtttc atctacaggt catatgattt tggttggtaa
    12541 tttaatagat tttaaggggc aatttgctga aatgtttgag gttgtaatac aacttggggc
    12601 tatattagca gtagtagtac tttattggaa aaagataaaa gatagcgtta tagaattttt
    12661 taaatttata tttactggcg gaaaagaagg aaagattggt tttagatttg gaatgaatgt
    12721 aattataggt tgtataccat ttgcgattat aggagttcta ttttatgata atataaaatc
    12781 attgtttaat ttacaatctg taattatagg atttatagtg ggtgggattt tattattagt
    12841 agtagaaact ttgtttagaa aaaagaatca ttcaacagat aatatagata aaattactcc
    12901 aatacaagct ttaaaggttg ggacattaca agttttgtct gcatggccag gtatgtcaag
    12961 gagtgcatct actattatgg gtggatggat agcaggactt aattctccta cagcagctga
    13021 gttttctttc tttttagcag taccagctat ggtggcttct tcaggaaaag atttatttga
    13081 atttgattat tcaataatga caccaacatt gtggattgct ttggtagttg ggtttatagt
    13141 agcttttatt gtatcaataa tagttatgga aaaattcgtg aattttttaa agaaaaaacc
    13201 aatgagagtg tttgctgtat acagaataat catgggtgta gtacttgcag tattagcttt
    13261 tactaacata attagtgtat agaaaaaata gatttattat ctataaaaat taaactaaga
    13321 taaattataa ttaacaatta tatatatgtt atttcaaaaa ttaaattagg aaggatagtt
    13381 aaataatgaa aattttaact gtaaataatt taagtaaagt atatggtaaa aaaataattt
    13441 tcaacgcatt aaatgacata aattttagta tagaagatgg agaatttgta ggaattatgg
    13501 gtccatctgg tagtggaaaa actactcttt taaatatgat ttctactatt gacaagccaa
    13561 ctacaggaac tatggaatta aagggaaaga atcctttatt gttaagaggt gaggaacttg
    13621 cattatttag aagaagagag ttaggttttg tatttcagga ttttaattta ttggatacat
    13681 taactatagg agaaaatata gtattgccat tgacattaga taaggtcagt gtaaaagagc
    13741 aagatgagag attgaatgaa gtatctacaa tattaggtat aaaagattta ttaggaaaaa
    13801 gaacttttga agtatcaggt ggtcaagctc agaggactgc tattgctaga gcattgatta
    13861 acaatccatc aatactttta gcagatgaac caacaggtaa tttagattca aagtcatcaa
    13921 aggttgtaat ggagctattt caaaagataa ataaagaaaa taaagttact actatgatgg
    13981 taactcatga cccattagca gcgagctact gtagtagaat cttattcata aaagatgggt
    14041 ctatatataa tgaaatatat aagggtagta gtagagagca gttttatcaa gagataatgg
    14101 atgtacttac attattggga ggcgataact aatgaatata aaacagtttg ctattaacaa
    14161 tatttcaaga aatattaaag cgtatttagg atacttagca agtattgtta tatcatcttc
    14221 actgctattt tcttttatta tgtttacaag tcatccagat ttagatgtat ctcaatttcc
    14281 tgattattta aaagaaggtc tcaagatgag taagataatt gcatatctat tcttattctt
    14341 ctttgtgttt tattcagtta gtgtgtttct taaaagtaga tataaagaat ttggaatact
    14401 ttatattaca ggtatatcaa aacgccaagt aatgaaatta atctttatag aaaatatgat
    14461 aataaatata gtatcttctg taattggaat aataataggc ttaatctttg caaagatatt
    14521 tttagtggtt atgtctactt ttttagaatt atcgccatta aaattctata taccatttaa
    14581 tgcgatattg tctactttaa tctattttat gattttagct gtattaacat caatatttac
    14641 ttattttata gttaaagaaa atcaggtgtt gaagttactt aaaggtacaa aaactccaaa
    14701 accagagcct aaaacatcac taatgcttgc tatattaagt atttgtttgt ttataatagc
    14761 gtattataat gctattacct caaccgacca atatacaaca tatctgcgct tagttccagt
    14821 tacatccctt actatagtag caacttactt gttcttttct caatttagtg tattttttat
    14881 gaagaagcta aaactaaaca agagatttta tagaaaaaat acaaatatgc tttggatttc
    14941 gaacttgatt tataaggtaa aggataatgc tagaatattt ttcttgataa ctataacttc
    15001 tgcagtagca tttactgcta taggtacagt ttattccttt tggaaagatg tagagcgtca
    15061 aattaattta atatatccta acacaatata ttattcaaca atgacattgc ataatgaccc
    15121 taaaaagcct gatagcaaag aaaaagacaa ggaaagaatg atgtttatag aaaataatct
    15181 aaaaaaagag aatgtagact atacaaggac taatggtgaa tttaaaactg tatttcccaa
    15241 gaaaagtgat tttaatgtca gaattatgaa agaatctaag tacttagaaa ttacagaaac
    15301 tataggggtt aagcctataa gttttgaaga taatgaatgc atatcattat tatcatcaag
    15361 tttaccagga aataataacg tcaaagaaaa tattattgta gggaatagag gtttaaaggt
    15421 ggcaaaacaa gtggaagaat gtgttatgcc agcatattac aaaaatatgt atgtggtaaa
    15481 ggataatttt tatgatagta tagaatcaaa atttatagtg gatagattta ctgcatttga
    15541 agtagaggat tcaagtaaaa ctatagagat atgcagagaa tttgaaaata aatttaataa
    15601 tgagtcaggg atgcaaccat atttgttttt ctctaaagaa ttaatgatag gaactgggaa
    15661 attaatatat tctacattta tatttttagc aatatttata ggtttaattt tctttgttac
    15721 tacaagtagt tttttatata ataaatttta tatggattgc caagttgata agaaaaagta
    15781 tgagcaatta aataaattgg ggatgacata taatgagatt aaaaaagctt caacaattga
    15841 gattggaata gtatttttgt ttccttatgt agtggctgtt atacattcaa tatttgccct
    15901 tactgcactg aaaaattctt ttgatataga agtagcatca tcagctgttt tggtaatggg
    15961 aagcttgttc ttggttcaaa tagtttattt tttaattgta agaaataatt atttaaaaga
    16021 gataaggtta aatttagtca atttttagtt actattatta aatgataata aaaagggttt
    16081 aaaattaatt aatattactg gaattataga tgtttatttt ttcagtaata ttttttattg
    16141 tattaactat taaaattttg tacaaatata aaatataata tggtaaatgt caaaattata
    16201 aaaaaattct acttatataa aatataaaga ggttatatgt acatatgtgt agaaataaat
    16261 aataaaaata tcaattaatg ttattagggg gggttactca ttagtaaatt agctaataca
    16321 cttagaatga tgatattaat tcaaagcaga ggcaaaatga aatgcaaaga attatcagaa
    16381 gagttggaag taagtgaaag gcaaataaaa agttacaaga tgtatttaga gcaagctggt
    16441 atatttataa attcaacacc tgggatttat ggtggttatg aaatagataa atgtaatagc
    16501 atatcattaa ttaaattatt agatagtgaa gtttcaattc tagatatgat aaattcacag
    16561 ttagagtata ataatgatat ttacaaaaat gaatttaata atattgtaga aaaaataaaa
    16621 gcagtattaa atacaggaga aaaaagcgat acatatatgg attattttac agttcaagca
    16681 caacgtaatt gtgattataa gtctgaaaaa aataagtgta atgaaataat tagagcatat
    16741 accacaaaac acaaattttg gatagaatat tattcattaa attcaggaaa tagtgaaaga
    16801 attgttcatc catatggttt atttaattat aaatcagata cttatatggt agctttttgt
    16861 gaaaaaagat ttaagtttat agactttaaa ttatgtagaa ttaaagatta taaggtttta
    16921 gaagaaaaat ataatgtaga taaaagtttt agttgggatg aatatagtaa aaatagtata
    16981 ggaatttata aaggagaaga aattaatgtt gttataaaaa ttagtcatcc attttcaata
    17041 attataaagg aaaaagtttg ggttaataat caacaaatca tagaatatga tgataaatct
    17101 ataatgttta aagctaaaat gagaggttat gaggagataa aaagttggat tttaagtatg
    17161 ggagcttatg ttgaggttgt agaaccagat agacttagaa atgatatatt gtcagagatt
    17221 gaaaaaatga aaaaaattta ctgatttttt caaataattt atacttggac caatatactt
    17281 cacggtctag tgttaatata ttaattgaga gaggtgatat tatgaaaatg aaaattgaat
    17341 ttagtacagg ttgtatacca atatcttata attcgctctt tatgagtatt ataaaagaag
    17401 caataagaaa atctaatgaa gattactata aaaacatgta ctattataaa gaaaagaata
    17461 ataaaaaaac taaaaatttt acattttcgg tttatataaa aaagtatagt attgaaggtg
    17521 acaattttat tatagaagat aaagtaatat taaatataag tactccagat ttagaattgg
    17581 gttttcatat atacaatggg ttaatgactt ctaaaaaatg tttatataaa gcctatgaac
    17641 ttacaagaat tagaatcgat ttatcaagag aaaagaaggt aacagaagaa agggtactat
    17701 ttaatgcatt gtctccaatc tgtgtaaagt ctaaagaagg aaaattcttg gagataactg
    17761 atgatagata catagaagaa ctaaactata taactaatga agtggttaaa aattataggg
    17821 gaaatggatt aaaaagaaag ttagaatttg aaaatatagg tctcaaaaag atagtagtta
    17881 aagagagctt aagagaattt aaaaaaataa caggtaaaga gtatcaatat attaatggtt
    17941 acaaaggtaa atttatattg aaaggtgata ttgatgattt aaatcttatc tacaatctag
    18001 gaattggttt tagacgtgct cagggatttg gagatgtaga tattttagaa tggaggtgag
    18061 ataaatgaag ttaagagttt atagaggaga ttggtttttt aatatgggta tagttggatt
    18121 tttaaatata ataaagaaag cagataaaca agctgaaata tttattatgg aagattatat
    18181 cgaatttgat agcttatttc ttgaaaactt tcatgagtat tattttaatt actttatgga
    18241 tgaatatgat gtatcaaaaa gaattaaaaa aaatattgat tacagtataa attttattaa
    18301 atctaagcct gatagaatca aagatggaat taagaaaatt aaagatagtg tgaaacaaca
    18361 aaatgataag attaaaaaat ttgatgaaga aaaatttaac ctgataaaag agaagctaga
    18421 tagcatgtct aagataaaaa gttatgatga atttgacagt ttagaagctt tagtagatga
    18481 gactatagat atatttaaaa taaaatcaat aaatgacagg cttacagcaa atctttataa
    18541 atatgtagtt caagataatt attttggaca agttagtttt tttaatgttg ctaaggcgaa
    18601 attagattta gatggattaa aacagataat gtttaatgat tatttaagac aaattatata
    18661 ttttggagag ttagcagatt tattagaaga gaatgactat gataagttga aaaactattt
    18721 aaatgataga ttaaatagta tagctaagga tataaatgaa aaaaaagtta gtaagtctag
    18781 tataaatact atagaaaaaa ttatgaagga aataaataaa aactttataa agaaaaataa
    18841 aagcatagaa gatataaaag agtatatgga tagtttagaa gtatgtgaaa tgtgtggttt
    18901 atataaggga atattagatg aatactcaga aagtaatttt gctccacttg gagtaagcac
    18961 caataatgct aggaatatgt tttggaatca ggcgtatgta ccatcaatat gtgatatttg
    19021 taagctaata ttgttctgta ctccagcagg ggctacttat acaagaaaga attatttaat
    19081 taatgaagaa aatgagtttt atttatttgt taacatggat acttctataa atgagctttt
    19141 tgaaagaaat aatagtttaa aagctcaaaa aagtgaatat tcagattcca aagatgaaaa
    19201 tccttttaat cagcttataa aaagtatagt agaagaaaat acattaaaaa gtgaatggca
    19261 acttcgtaat atactttttg tggaatttaa agcaagtata gattctaaaa aatgtaaaat
    19321 aaattatttt aatattccaa cttatttagc aaaatttttt acagacaagt atgcaaataa
    19381 aaaaatacaa agtatctatg attacaagct taaatcaaat gtactagatt tactcttgaa
    19441 aaatagggac ttgaagcatc taactaataa cattttaaga aataaagtta aaaatgatat
    19501 ggaaagcaac aacaaatcaa atatatcagg aatagattgt tttagagtag tccaattaag
    19561 agcattaata aatagctaca aaaagggggt atataaaatg gatagtaaaa atttggagaa
    19621 gaatgatgaa aagctgagaa taatttatta tttaggttgt gatatacatg actattttgt
    19681 taataaaaat tctaaaaata aaatagatgg agtaagctat aaacttttaa attcagttaa
    19741 agtcggaaat aaaagtgatt ttatggatac aattataaga gtttttatgt cagctgaaaa
    19801 acagattcca gcatttattt tagatataga aattgaaaaa gatttagact ttgaatctat
    19861 aggtcatgct tttatatctg gattaatttc tggaaaatat gaaggaaaag acaaactacc
    19921 aaacgaaaag gaggaaaaat aagatgaaaa gagggttaac atttacagta atagcacagg
    19981 ctcaaagttt aaactatggg gaagggatag gtaatatatc agaattaaaa aaattaagta
    20041 gagatgatgg aaatatatat acatttgcat ctcgccagtg tttaagatat gacatagtac
    20101 gattagcagc agaattgttt aattggaatt tacaggttgt cgataaagaa aaaggtacta
    20161 ttcaatttaa agacaatata agtataagag aatcagaaga aatggattta tttggatata
    20221 tgaaaacaaa taaaaaagat gagaaagata aaaaaggagg ttctttgact agagaagcta
    20281 ctgtaagatt aagtaatgca atttcccttg agccatatag aagtgacatg gactttttaa
    20341 ataataaagg attagcagat agaataggag aacatcctaa tcttgctaac atagagcaac
    20401 atttaagtta ttatacatat acagtgacta tagatttatc taaaataggt aaggatggag
    20461 atatagaact tgataataaa gagaaatgta gaagagtagt agaattttta gaaataataa
    20521 aagtattgaa tagaaatatt agaggtagac aagaaaattt atctcctcta tttgtagtag
    20581 gaggagtata tgaaatagca aatccatttt tcttgggtag aattaaatta aaaggagata
    20641 aaaatggatt taaaataaat aagcaagcta tagaagaagt aattcaaggt acttttttag
    20701 gaaaagattt aaaagaattt acctatgttg gaatggtaga tggggtattt ataaataaag
    20761 aagaatttaa gggattgttt gaagataatt ttttaagtgt agataaattt tttggacaac
    20821 tagttaaaga agtaaaggaa tattatgggg tgaattaata tgaaggtttt gaaattagat
    20881 ttatttcaag aaactgcatg ctataaaaaa ccatttgcta tgaagattac agagacatat
    20941 ccactgcctc catattctac aataaatgga ttaattcaca aaatattaaa tgctacagaa
    21001 tatataccat ttaatataag tgtacaggga acatatgaaa gtatatttaa taattaccag
    21061 acaacatatt tttataaaaa agatagtatt acatctatgc caatgaatag tcatatgcta
    21121 ttgaatgtaa atttgataat tcatataggt ggggattttg atttattgga agaaatatat
    21181 gatagtttat taaattatga cgagcactta tcattaggta gaaaagaaga tttagtaaga
    21241 attaatgata ttagatttgt agaagtcaat aaatttgaag tagatgagga tatacaatta
    21301 gatgattatg aaaattataa gttatcagaa tgtaatataa gaatgcctat atatatacca
    21361 aaaacaagtt tacaagatac agatatagat ggtataagtt acagactcaa taattactat
    21421 gataataatg ctgtggaaga taaaaaaagg gtttggaata aggtagatag ttattatgtt
    21481 gaggatggaa atactatatc aattggagat atattattag ataatgaagg agatttatta
    21541 tattttaata atataaatta ggagggagag tatgttatat gctaaatcta atccagtgga
    21601 aacacttaga gaacatactg atgaactttt aaaacaaatg aatgtattaa gagaaagtta
    21661 tggaaaaaat ataaatagct tagattttct agaggaagag atattttggc aattacttga
    21721 ctttgttata gaatttcatg atattggaaa agcattttca ccgtttcaag agttaataaa
    21781 aagcagaatg gatactaaaa taaatgaacc taaaatagta actcatttag aaaataatgt
    21841 aggccataat tatctttctc ctgcatttat tgattatagt tatatagaca ggaaaaaaaa
    21901 taaagaactt agagcagtat taaatcaagt tattgtatat catcatgaaa gagatatctt
    21961 tatagataaa gattttaaaa atttaataca aaaaatatta gatgaagatt taataaataa
    22021 agtttatgaa ctacagcgtg aatttaaagt tagatatcca ataaaaacag aaaaattgag
    22081 taaagtatat ctacaaagtg tagaaaaaag aatagataaa aatcacaagt actataattt
    22141 atatattatg ttaaaaggaa tactacatag actagaccat agtgcttctg ctcatgaagt
    22201 tgtggaatgc aataatgtta taaatatagg agaacagaca gaaaattatt taatgaaaga
    22261 gtttggtagt ttgagagagg ctcaatcatt tgctaaatct aatagaaata agaatataat
    22321 actgattgca tctacaggaa tgggaaaaac agaaactgct ttgatttgga tagataagga
    22381 taaagcattt tttacactac cattaagagt aagtataaat gcattatttg atagggctaa
    22441 aaatataatt ggagtaggag aagcaaatga tacattctta ggtctgttac attcaacagc
    22501 aatagattat ttagaagaaa gtaatcagga aaattcaagt gagattgtag atttagcaaa
    22561 gttattatct tgtaaactga cattttccac aatagaccaa atatttaaat ttcctttttt
    22621 gtatagaggc tatgaaaaag tgtactcaac attagcatat tcaaaagtag taatagatga
    22681 gatacaagca tattcaccag aaatagcagc tgtattggta aaaggtatag aaatgataca
    22741 taagataggt ggcagattta tgataatgac agctactatg ccaaccatat atatagatga
    22801 attaaaaaaa agaggtgtaa tgaatagtaa cttagctgac ttgacatgta acacagaaaa
    22861 aataagacat tgtgtgtcta ttgtagaaaa ttcaatagat gaaaacttag gtaaaataat
    22921 acaaagtgga atgaataaaa aagttcttgt aatagtaaat acagttaaaa gtgctgtaga
    22981 aaaatatgag ttaatagaag aaatagttaa accaaaagga atagatgtca acttaaatct
    23041 tttacattct atgtatatac aagaagatag agcaaaatta gaaaaatata taaaagaatt
    23101 tgcagatagt gatagtaatg gtatttggat tactacacaa ttagtggaag catcccttga
    23161 tattgatttt gatgagcttc atacagaaaa ttcaacactt gacagtctat ttcaacgatt
    23221 tggtagatgt tatagaagtc gtgagtatga agaaaatagc ccaaatatat ttatatatac
    23281 agaaaaagct acaggaatag gtagtattta tgataaggat attgtagaaa aaggacttga
    23341 gctactgaaa acttttataa atggaaaaga atgtgtgaag atgaaagaaa aatataaggt
    23401 agaaatggtt aagatactat actctaaaga aagtctagaa ggtacagctt ttgaaaagag
    23461 atttaccagt gctttaaata ttttagatac tataacgcca tatagtttag gttctaaaga
    23521 tgcacaaaat atacttagaa atattgaagg atatacagta attccagagg atatatataa
    23581 taaaattgaa gaaactttaa tcaaagatta tgaagagttg ggacaagagc ttataaatgc
    23641 atatagtaat gatgatagac aattgataaa taaaataaag tctaagagaa aaaaagcaag
    23701 aagagagata attaaaaaaa ctgtaaattt accaatatat aaagctaaac aaaatgtaat
    23761 tgacatacag gtgaaaggtc ttgaagattt aaaaatactt ttatataaat atgatataca
    23821 cgaaaataag catacaaaac agatatttgg taaaggtgtg cttataagta atgaaataga
    23881 ccaatttatt tgatttttat attaacaatg tggctaaaat ttactaaaga aggtgatttt
    23941 gtgccaatag atttagaagt attaaaagtt caaggcgtaa aaataaatta ttattatgta
    24001 tgtaaaagaa aactatggct attttctaaa ggaataacta tggaacaaaa tagtagtaga
    24061 gtattgtctg gaaagatagt acatgaagat tcatataaaa gaatgaaaaa taaagaaatg
    24121 ttgattgatg atatcttgaa gctagatata ataaaggacg agtatgtaaa agaagtaaaa
    24181 ataagttcaa agatgaaaga agcagatgaa atgcagttat actattactt atactattta
    24241 aagaatagta tgggtataga gaaaaaagga actataaatt atgttaagga aaagaaacaa
    24301 gaagaattga tattgacaga agaaaaagaa aaaattattg aaaacacact tataaatata
    24361 aatgaaataa atatgcagtt atctcctccc aaaattgaga aaaaacatta ttgtacaaaa
    24421 tgtgcttatt atgaattttg ttttgtgaag gaggagtaac aatgtataaa gactattata
    24481 ttataagtaa tggaaatata aaaaggaaag aaaatacgat ttactattac aatttagaag
    24541 gtgagaaaaa aatattacca gtagaacaag ttgatgatat tcatatatat ggagaagtag
    24601 atttaaacac aaaacttata aattacataa gtaaatatgg ggtgatgctt catttctaca
    24661 attactatgg atattattca ggtacatatt atccaaggaa gaaaaatgta tcaggattca
    24721 gtttagtatg tcaatcagcc tgctatttag ataaaaatga aagattatac ttagcaaaat
    24781 cctttgtgga aagtgcatca taccatattt taagaaatat gagatattac aaagttgatg
    24841 aaagtttaat tgatactata aaggatgaac taaatgattt gaatgatgtc aaagaaatat
    24901 cagaacttat gggtaaagaa ggcagaataa gaaaaacata ctataaatca tttaatcaaa
    24961 tattaaaaga tgattttgaa ttttataaaa gagaaaaaag acctcccaaa gacccagtaa
    25021 atactcttat gtcttttgga aatagcataa tgtatacgaa tgttttaagt gagatatata
    25081 agacacaact tgaccctaca ataagctttt tacatgaacc atcaacaaag agattttctt
    25141 taagtttaga tattgcagaa atttttaagc caattatagt tgacacaata atttttagcc
    25201 tgattaataa taaaagaatt aataagaatg attttgaata tcaagacaaa atttgttatt
    25261 taagtgaaaa aggaaagaag aaatttttgc aagaatttga aaataagatg cagacaacta
    25321 taaaacatag aaatctaaat agaaaagttt catatagaat gtttataagg ttagagtgtt
    25381 ataaattaat taaacatttt ataaatgatg aaaggtacaa agttttaaag gtgtggtggt
    25441 aagtatgttt gttattgtta cttatgatat tgttgaagca aggtcgttaa atagaattag
    25501 aaggatactt agaaaatatt tgacttggac gcaaaattct gtttttgaag gcaatattac
    25561 tgatggaaag ttacataaat gtatttctga aatagaaaat attattgata atagcgagga
    25621 ttcaatctat gtttatgaga taaaaaatcc taattcaatt aaaaagaaat gttatgggat
    25681 tgataagtat tctgatgaaa tgtttatata ggtttgcagt gagcgatatt tatgctaaaa
    25741 taggtgttaa cagttggaat ataagggatt gaaggtgtat gataactgtt atcaattgca
    25801 ctactgctcg ctcactgcaa attttgatgt ttttattgaa ttataattgc ttgattgaag
    25861 tattttcaat gtattcaatt atacctattt tggggtttta tattaactaa gtggtatgta
    25921 aataagcaac tatagtagaa gcaaaagcga caacaactaa aggttttata ttaactaagt
    25981 ggtatgtaaa tttggttaac ttaagtgcta tgaaaggaat taatgaagtt ttatattaac
    26041 taagtggtat gtaaatttaa aggtgcaagt cttaatactt gttacatgag ttgttttata
    26101 ttaactaagt ggtatgtaaa taacaaagaa ccatttgaat cacgaaaact aaaaaacagt
    26161 tttatattaa ctaagtggta tgtaaattta ttaaccttat cagaaacctg accatcccaa
    26221 ttatagtttt atattaacta agtggtatgt aaattccatt tgtctaatgc ttctaactct
    26281 ttttttatac gttttatatt aactaagtgg tatgtaaatt ccaaaatggg cttggagtta
    26341 agagttgtat aagaaacgtt ttatattaac taagtggtat gtaaattaat tacacactcc
    26401 cttttaacga acatatttta gattgtttta tattaactaa gtggtatgta aatagactcg
    26461 acatagaatc ggttactaaa tccgagggtt tcaggtttta tattaactaa gtggtatgta
    26521 aatactaaac ctttttgttt acttttattt ctcattttac gttttatatt aactaagtgg
    26581 tatgtaaatc cggatttttc tgcttcgact gttgttattg agacttgttt tatattaact
    26641 aagtggtatg taaatagtaa ttccatgcaa tcttttatat tgctttttaa cctgttttat
    26701 attaactaag tggtatgtaa atagatatac aaggtgaaag tgttgaaatt tcaatcttgt
    26761 tttatattaa ctaagtggta tgtaaatatt cttagatgtt ataatttgtg ttgcatttaa
    26821 atcgttttat attaactaag tggtatgtaa atacaatatt attgttcatt tcatttaata
    26881 attctagtag ttttatatta actaagtggt atgtaaattt gtttatacct ttaatcttta
    26941 aaattaaata taaaagtttt atattaacta agtggtatgt aaatcattgt atactaagct
    27001 tgatatagtg caaaatgaaa cgttttatat taactaagtg gtatgtaaat actaattggg
    27061 ttaaacaaat ggatataact aaattagttt tatattaact aagtggtatg taaatccaac
    27121 ccttcgcacg aatccgtgcg acgaaatata aagttttata ttaactaagt ggtatgtaaa
    27181 ttgtaaaaat attgcttagc atattgatat cactaactgt tttatattaa ctaagtggta
    27241 tgtaaataca agaggttttt cagcaatata tgtacttcta taatgtttta tattaactaa
    27301 gtggtatgta aattcatcaa tattaatttt gggaatatca acattttttg cgttttatat
    27361 taactaagtg gtatgtaaat gcgataagag attcgagtct ttttactggg cttaatcgtt
    27421 ttatattaac taagtggtat gtaaatagga taaagaaaag actcacacaa gacacagtgt
    27481 caggttttat atcaactaag tggtagataa gtagaatatt agcaatatca acgagtattt
    27541 agaaacttat tttatattaa taaagcagta tataaaattg tagaataaac aatagcatat
    27601 actaaaacat ccaccttata ttaactaaat catatctaaa taaaatgcac ttacctataa
    27661 acattataaa atcaatacaa aaatgaggtg aaacaaaatt tatgataaag aaattaaaca
    27721 ataaagacat aaataaaatc atggaaatat gggaaaaaag tacaatcaaa gcacatgact
    27781 ttataagtaa agaatactgg caaaataact acaatactgt taaaaacgaa tatataccta
    27841 tatcagatac atttgtatat gatgatggag atgaaataaa aggatttata agcataatag
    27901 ataaaagctt tataggagct ttatttatag aacccaaata ccaaaatcta ggtatcggag
    27961 gtaaactttt agattatgca actaaaaaat ataaaagtct aagtttagca gtatataaag
    28021 ataataaaaa agcagttgtg ttttataata aaaaaggttt taatatagta aaagaacaag
    28081 taaatgaaga ttcaggattt aaagagtaca taatggaata tagtaaataa tatgattaca
    28141 ttct
//
LOCUS       DAEQJM010000049        27559 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.049, whole genome shotgun sequence.
ACCESSION   DAEQJM010000049 DAEQJM010000000
VERSION     DAEQJM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27559
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.049"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     repeat_region   716..1673
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=716..744
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            2890..3045
                     /locus_tag="KRQ43_002573"
     CDS             2890..3045
                     /locus_tag="KRQ43_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HBH2742923.1"
                     /translation="MALDVKIEVKIIKDVVILNIIHWKKETSLLTVKIARGQGDLSYV
                     KYFTNES"
     gene            3291..3542
                     /locus_tag="KRQ43_002574"
     CDS             3291..3542
                     /locus_tag="KRQ43_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742924.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(4751..5134)
                     /locus_tag="KRQ43_002575"
     CDS             complement(4751..5134)
                     /locus_tag="KRQ43_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742925.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            5261..5605
                     /locus_tag="KRQ43_002576"
     CDS             5261..5605
                     /locus_tag="KRQ43_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742926.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSSNEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSK
                     IYSKTVFLILIQ"
     gene            5788..6003
                     /locus_tag="KRQ43_002577"
     CDS             5788..6003
                     /locus_tag="KRQ43_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742927.1"
                     /translation="MHINQTGFISNGLGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFELIATLVREGSSWAFNFIVQP"
     gene            complement(6989..7306)
                     /locus_tag="KRQ43_002578"
     CDS             complement(6989..7306)
                     /locus_tag="KRQ43_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742928.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYISIGLFTRRLDITIIAIILVATITVILYYLVRKRY
                     ITI"
     gene            complement(7598..8167)
                     /locus_tag="KRQ43_002579"
     CDS             complement(7598..8167)
                     /locus_tag="KRQ43_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742929.1"
                     /translation="MKLRNPKIKKLLSVALLAALIGIPIGQTANAMEISNNVPSYIEN
                     NPTTIEDLEINDSQLPKPGTVTYIDINKLIKNLKENGIDTTLIENELYYRKAGTNKIV
                     WTKTGFDLYLSKGVALTLAGAGTGVAGLLAGAIPGIGQYLAAAIVGAITMHLGSNITS
                     GKIFKFKKMRYNKGGAYVTKYYLQSVRNQ"
     gene            8611..9001
                     /locus_tag="KRQ43_002580"
                     /pseudo
     CDS             8611..9001
                     /locus_tag="KRQ43_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            9321..9830
                     /gene="vanZ1"
                     /locus_tag="KRQ43_002581"
     CDS             9321..9830
                     /gene="vanZ1"
                     /locus_tag="KRQ43_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HBH2742930.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(9932..10126)
                     /locus_tag="KRQ43_002582"
     CDS             complement(9932..10126)
                     /locus_tag="KRQ43_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HBH2742931.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIREFQDTIIL"
     gene            complement(10641..11033)
                     /locus_tag="KRQ43_002583"
     CDS             complement(10641..11033)
                     /locus_tag="KRQ43_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2742932.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            11601..11963
                     /locus_tag="KRQ43_002584"
     CDS             11601..11963
                     /locus_tag="KRQ43_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742933.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            11947..12663
                     /locus_tag="KRQ43_002585"
     CDS             11947..12663
                     /locus_tag="KRQ43_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742934.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVVEFTEEDEEYEEELKQNIIE
                     NIKKNFDEKKLVQVYKYRGV"
     gene            12683..13102
                     /locus_tag="KRQ43_002586"
     CDS             12683..13102
                     /locus_tag="KRQ43_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742935.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            13092..13616
                     /locus_tag="KRQ43_002587"
     CDS             13092..13616
                     /locus_tag="KRQ43_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742936.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYVDENNNEESISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVLITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            13928..14485
                     /gene="efp"
                     /locus_tag="KRQ43_002588"
     CDS             13928..14485
                     /gene="efp"
                     /locus_tag="KRQ43_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBH2742937.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            14577..15032
                     /locus_tag="KRQ43_002589"
     CDS             14577..15032
                     /locus_tag="KRQ43_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH2742938.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCPSCDDRE"
     gene            15195..15905
                     /locus_tag="KRQ43_002590"
     CDS             15195..15905
                     /locus_tag="KRQ43_002590"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBH2742939.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            15959..17029
                     /locus_tag="KRQ43_002591"
     CDS             15959..17029
                     /locus_tag="KRQ43_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH2742940.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            17057..20611
                     /gene="smc"
                     /locus_tag="KRQ43_002592"
     CDS             17057..20611
                     /gene="smc"
                     /locus_tag="KRQ43_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBH2742941.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKILEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEASKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKVSLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEAYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSIATEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIGSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            20638..21918
                     /gene="ftsY"
                     /locus_tag="KRQ43_002593"
     CDS             20638..21918
                     /gene="ftsY"
                     /locus_tag="KRQ43_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBH2742942.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDSLENLEETIFSG
                     LEEEVIDKVEDIEEKTEESVNNEGTEEIENFEKIEVEMDSNAKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            22021..22389
                     /locus_tag="KRQ43_002594"
     CDS             22021..22389
                     /locus_tag="KRQ43_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBH2742943.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            22386..23738
                     /gene="ffh"
                     /locus_tag="KRQ43_002595"
     CDS             22386..23738
                     /gene="ffh"
                     /locus_tag="KRQ43_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBH2742944.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMAELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            23776..24048
                     /gene="rpsP"
                     /locus_tag="KRQ43_002596"
     CDS             23776..24048
                     /gene="rpsP"
                     /locus_tag="KRQ43_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBH2742945.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            24113..24340
                     /locus_tag="KRQ43_002597"
     CDS             24113..24340
                     /locus_tag="KRQ43_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBH2742946.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            24448..24963
                     /gene="rimM"
                     /locus_tag="KRQ43_002598"
     CDS             24448..24963
                     /gene="rimM"
                     /locus_tag="KRQ43_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HBH2742947.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            24972..25667
                     /gene="trmD"
                     /locus_tag="KRQ43_002599"
     CDS             24972..25667
                     /gene="trmD"
                     /locus_tag="KRQ43_002599"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBH2742948.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVYIYNIRDFSNN
                     KHKKVDDYPFGGGVGMVMTPQPIYDTYKHIITTHNISNPSVIYLTPKGKVYNQSIAKQ
                     MSLKEDIILLCGHYEGVDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            25852..26202
                     /gene="rplS"
                     /locus_tag="KRQ43_002600"
     CDS             25852..26202
                     /gene="rplS"
                     /locus_tag="KRQ43_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBH2742949.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            26523..27419
                     /gene="ylqF"
                     /locus_tag="KRQ43_002601"
     CDS             26523..27419
                     /gene="ylqF"
                     /locus_tag="KRQ43_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBH2742950.1"
                     /translation="MSNEYEEYLMDDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINNIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIAATV
                     LNEFRDGKIGNITLEVPENVKR"
BASE COUNT        11451 a         2651 c         4560 g         8897 t
ORIGIN      
        1 acaaagagtg acttacgagt tgaatttaaa tttatattta aatccaaaaa ataaactctg
       61 tttatgatga actccactct aacgcaaaat agattgtagt tcttcttgct tttattatac
      121 cacaaaacat tataaataaa actgttgttt ataaaaaaat gcaaagtaaa attttttata
      181 aacaatgata aaaattttat tatagagcta ttaacttatg aaatatctgt aaatgagtag
      241 atatttcata agttaatatt tattgtttgt ataaaatatt tggtaaaaat aagtaagttt
      301 tatatgttat aataattgta gcaagaataa taatcgaaag cagcaagcat gtcagctggt
      361 gttatatcag tttatattta tgataaaata aaaatctccc aaacgccaat aaggatgatt
      421 taaaaaaata atattttcac ttaaaaataa tcactcttta taggagtaaa ttattttctt
      481 gattttatta tactacaaat tggtacagat atttaaaaat aatatattca taatattata
      541 aaattataaa tagttttgca gtgagcgata tttttgataa aatagggcct aacagttgaa
      601 atataaggca ttgagggtat gtgataaatg ttatcatttg cactactcat ggttcactgc
      661 aaatttgaga gaattgtata gatgtaagtg ttggaaatac tcaatttatt ttggggtttt
      721 atattaacta agtggtatgt aaagtctcca tctccaatta acataaataa ttcatccgct
      781 ggttttatat taactaagtg gtatgtaaag ccgcttggca aatcataaga aggattattt
      841 tctccaacgt tttatattaa ctaagtggta tgtaaagaaa ataaaagagt ttgaattacc
      901 cattttttca tggttttata ttaactaagt ggtatgtaaa gtacgacatt gaataaaatg
      961 ggtacagaga caatttataa gttttatatt aactaagtgg tatgtaaagt ttataaatct
     1021 tttaatgact gtctctgatg gtacaggttt tatattaact aagtggtatg taaagaaagg
     1081 aatagatgat atgattgcta atgctgaaca acaagtttta tattaactaa gtggtatgta
     1141 aaggggtctg actttaatat atatatatat atatataaat tgttttatat taactaagtg
     1201 gtatgtaaag ttataaactc ccacgacaaa attaactata acctcgtgtt ttatattaac
     1261 taagtggtat gtaaagagtt ttaaagaggg cagacctaaa aaatatacta aaagttttat
     1321 attaactaag tggtatgtaa aggcagaaga tttagcgact gttgttgctg aatgggatgg
     1381 ttttatatta actaagtggt atgtaaagat taaattgctc agtctagtac ttaaagaatt
     1441 ataaggtttt atattaacta agtggtatgt aaagttgcta tgatttaatt atacgacgtt
     1501 ttgtctttaa aggttttata ttaactaagt ggtatgtaaa gtgctgtgcc acaatttgat
     1561 gcttctatag ctaaattcgt tttatattaa ctaagtggta tgtaaagctt ttaagtgcat
     1621 caaaggagtt acaagctata tttagtttta tattaactaa gtggtatgta aagacagatc
     1681 taatatcaaa ataaggttat gacttttaaa agcatagcca tatcagtaaa aatttaatta
     1741 tcatttaaaa aataaatttt tatttaaaga atacacataa atatttccag acttaactct
     1801 cttaaaccat tttcatatcc tttagtagat acttttgtta ttttttaatc tttagtaact
     1861 tattcttgag tgaatctctt attttttcta agctatttca agcttctcaa aaaattctat
     1921 atttatattc atcacacata taatacaatc aattcagttt taattgccaa tatttagttt
     1981 ttctgtatct gataaaccaa gaacataatc agtatataaa ccaaaaattt tagcaaatat
     2041 tattaaccca tcgtctcttg ttggtctttc accagattct attcataaca cttgtattta
     2101 tatttgtttt ttcaagcaat tctttttgag aactattcat attttcccta gtatatttaa
     2161 ttctttgatt tacatctata cataattacc tcgaaaaatt tctgttttgg aaatattgtt
     2221 attgaaatat agcaattaag gtgaatatat gaaaaagata cactatgatt ttataaaaaa
     2281 gaagacatac ataaaattta tacttacaaa gtgttgcaaa agagttaggt tttaaaaatg
     2341 catcaactta ttttaagtac aggaaggggt aatattcaat tagagttgat atgttaccta
     2401 taaactatct aagatacttg attatgatat agaaaatttt tttacaaatt aaatttctaa
     2461 gatagaaatt taattaagag gatgatgagg atgaataatt tacaagtaat ataaagaaat
     2521 aataagagaa ttttaaatgc atagcaacta gcagatatat atgaaaatga tgtaaacaat
     2581 atataaacta acttcaatag aaataaagag aatgtaaatt atgttttatt acaattcgag
     2641 tatttgaaag aatttaagaa ctaacctact aatagtcagt tgatttcaaa acattctagt
     2701 caattatacc tttggatcga aagatgtgca aatagacact gcaaaatatt agatattgat
     2761 aaaacttggg aacaatttga caatttagag aaaatatatt tcaagattaa gcgagagaaa
     2821 ctaagctgta tagaagatgt attaatagaa aatttaagat ttaaggatac aaattaataa
     2881 agcaataata tggcattaga tgtaaaaata gaagttaaaa taataaaaga tgttgttata
     2941 ttaaatataa tacattggaa aaaagaaaca agtctattaa cagttaaaat tgctagaggt
     3001 caaggtgatt taagttatgt aaaatatttt actaatgaga gctaagagct tcttaacaag
     3061 agttttggtg tgtctcttga aacaatgtta acaattaata aaagacgaat ggcagaagaa
     3121 ggcgtatgta agtttaaaag agataagtta aacaaactag atactatata agaggataag
     3181 aaacttatag aagaatatgt tacttttgta aaggatttag ctttaaaata tagaatataa
     3241 agtgatttta agtaaaaatt gtaacaatta aataagtata agacaagttt atgagttcat
     3301 attttataac aaggggtgat gttatgaaaa tactacaaca atttaaacca tacaaatatg
     3361 ataaagaaaa aaatatagaa tatgatgaaa aaattatagc taatcaaaac acagaagttt
     3421 atatagtata tccacgtata tctgatgaag aaaataggag aagatgggaa gagttcaatg
     3481 aagtagctaa agaagtagct attaatatag ctatgaagaa agttgagaca gtagaaagtt
     3541 aagagaatag agaagttgct aatacttagc actttctcat agaagaaaat tggacaacta
     3601 tttttaaata attaggaata aaaaagttaa atcatatttg aaaaaaggcg ataaaattgt
     3661 tgagtattgt tattagtaat aagaatgtat taaaagaaat tataagtttt tagtaaatat
     3721 agtatttaag gatattaaaa ctggtaaaaa atatcattta gactattaaa taaaaaagtg
     3781 ctggtcaaag taagcaacac aataaataaa aaaacttata gaaattataa gataaaaaga
     3841 tgagatttga aatggttgaa gttaatataa aaattaaagg tgaagtaagt gaaataattg
     3901 actcaattag aggtatattt aatagctttg atgaagagtt aatattagat ataaaatcag
     3961 agtaagaata taaaggtaga tacgtagaaa gttataagta attcaagact taaattaatt
     4021 tctagttttt ttaatgcaaa aatttaataa atttcaaaat ataataattc tgacatctaa
     4081 aaagagctat taaaaatgaa taatattgac tattaagata tgaatagtgt acatatatta
     4141 aattaagata tcaagtaggt taattttata taatgatggg gctcaaattg aagaggcgat
     4201 ataaaaatgt attaatatat ataaatataa gaactataat acatattaac tgtaaaatta
     4261 aatttataga gttatattta acatttaatg aactgaaaaa taaattagca aataatgaaa
     4321 aaacaacagt aataaatgag aataacaaag cattctcagg attagtggat ttttctaatt
     4381 gagctttaat cctagtttgt tcaatttcga tatttctaat attattagta ttatcaattt
     4441 atttgtaata attatcaatt tttgcgaaat atttttgata atttatagaa ctttatatat
     4501 tttccttaaa gtatttttag cccttattgt ttggtttcca attttaaaac tcataaactc
     4561 ccaataaatt catgtataat ataccttaat ttataatata tttaagagtt tatttcagta
     4621 atttttcgaa cgattttgat atatttcatt tatagttttc aaaaacttat acaaaaaaga
     4681 gtgtttcatt tttctaaaca ctctttttat aagaatttga ataataattt tttaaaaatt
     4741 gataatatgg ttatttcttt ttcaagttta tagtttcctc atttccattc caagatataa
     4801 ttagcttgta actagattct ctatttgaat aaagacctgg tctttgtatt tttattgctt
     4861 tttcttgacc tgcttctaaa atttcatttt ttacaactac aactgcatct tcaccatcta
     4921 taaattgata ggaataatta aatttttgtt caactacatc tttactattt ttatatttta
     4981 tttctaattt tgagtgtcct tcagtagtta caaatttagc tttccaattt tctgattctc
     5041 caataaagac atttttatca ttttttatat taagtatagc tatcacagag attattaaaa
     5101 ctataagaat acctataaaa aattttttcc tcatatcaat ccctcctttg aataattata
     5161 acatgagaat agttattcaa tactaatttt aaaaatattg tggatttata ttctattaca
     5221 atagaatgtc tgttataaca aataaaaagt aaggattaat atgaattata ggttaaaaaa
     5281 atctgtaaca actattttat ctttactcat aatgacaata ctattaccaa caaatgcaag
     5341 tgctagtaag gtagaagatt catctatgaa agtaatgtat tcagagaaac aagtaacaga
     5401 catggacaaa ttatacgata tggctaaaaa tggaattact gatgttaaaa gttccaatga
     5461 aaaaggtata atcaaaaatg caagaacagg agagtccata tacgttgatt ctatatcaac
     5521 aactcaatta ttagaagtta aacaatctaa aaatttaaca tcaaagatat attctaagac
     5581 agtttttttg atactaatac aataaagcct cttagaaaag caagtatatc agaagatgga
     5641 tgggataaaa ctggtggtgt aaaagcatct ggtacagtta catatacaat atcaaaagga
     5701 gatggagcat ttcaatatat ttccgttagt aaagtttctg gaaactggtc tattgcagac
     5761 ggccagattc gtgtaacaaa tagaagggtg catataaatc aaactggatt tatttctaat
     5821 gggctaggaa ttaagcagca acaaaagaaa gagccaacat caaattcttt ctcatataat
     5881 gcaccttcta gttggaaacc agtaggtaga gattcagttc aatacaattg tgggtttgaa
     5941 ttaattgcaa cattagtaag agaaggaagt tcttgggcat tcaatttcat tgttcaacct
     6001 taaaatattt taagtgaatt ttattaaaat caaagatata catatacttt aaaattagag
     6061 aatgtaaatt aatttgtgtt tttaaagata attcctacgt tatagtaaca attgcttatt
     6121 tactattaat atttcttaat atatgaattt tattttaaca aattataaaa aatgtatatt
     6181 gagatgtttt taaatatttt tggaaattat atatattata acaattatag caaattttta
     6241 gggtataatt tttaaaatta tattctacta tcaaaagata tgaataaatg attgtatata
     6301 ttatatcaat ttttatattt catagtccat tttttcatca cattttcgct tgtcaagaat
     6361 aatatcttta agagtgaagc gtttgatgta aatctggact ttgtttttga gacatttttg
     6421 aaatatttat taaatccttc gattatactt gtaatatata ttatagatat tacttatttt
     6481 agtaaaacta aaggctgatg ctacaacatt ccagttattt ccaaacgttt taatttctga
     6541 agtatactgt ttacattatt tttaatctat tttatctaaa gtcgataagg ctttttattc
     6601 attaactgac ctatatacag atttaaaatc acttattaat tcttttgagt ccttgtatga
     6661 aacatattta aagtatttct tatctaatgt attaaacatt tttgtattac agaatgagga
     6721 taacttgtag ctattgtctc tttgaaataa gtcatctgta tttactccta aaactactta
     6781 tatctgtaga ttttataagt tctccatctt atataatttc tttgattaat tgttttctta
     6841 aattattcat aaaaaaatct ccgttacgat atttgattat atttaaatca ttgccataaa
     6901 gaagactttt attaactttg aaaaacaaat tattttacat tactggtgat tagttgctac
     6961 tttcttttga tattaattct attagatttt atatagttat atatctcttt ctaactaagt
     7021 aatataatat tactgttata gtagctacta atattattgc tattattgta atatctaatc
     7081 ttcttgtaaa taagcctatt gatatatact caagacctgt tacatagcga taaagtactt
     7141 ctagtttaac agtttttttc ttatctatat ttccatatat tgattctaat ttattaaaat
     7201 attttttact acaaaaagca gttttaggtt taattaaata tattattgta gttcctatta
     7261 taactattat tccaataagt ataagattga tatttccaaa atccatagca gatacctcct
     7321 gttaaattta cttttcttaa tcaaagtata tcagtaacac aagtataaag agtatctaaa
     7381 atattacaaa tattaaatga gaaaaagatg gtaggttaac cccaccatct tattttttat
     7441 ctattaataa atgatgctac aaaagttagt ataaaaaatg aaacaaacaa tataatgaac
     7501 ttgtgtaatt tacttagttg aaatacttta ttacaaaaga ataaaactag tgctgagata
     7561 attgcaaaaa gtagatattt tataatcatt ttatcaccta ttgatttctt acagattgta
     7621 agtaatattt ggttacataa gccccacctt tattataacg cattttttta aatttaaaga
     7681 tttttccaga tgttatattt gaaccaagat gcattgtaat tgctccaact atagcagctg
     7741 caagatactg tcctatacca ggaatggcac cagccaaaag ccctgcaacc cctgtaccag
     7801 caccagctaa agttaatgca actcctttag aaagatataa atcaaagcct gtcttagtcc
     7861 aaactatttt atttgttcca gcttttctat aatataattc attttcaata agagtagtgt
     7921 cgataccatt ttccttaagg tttttaatta gcttattaat atctatgtat gtaactgtac
     7981 ctggtttagg taattgagag tcattgattt ccaagtcttc tattgttgtt ggattgtttt
     8041 ctatataact tgggacgtta tttgaaattt ccattgcatt ggctgtttgt ccaataggta
     8101 tacctataag agctgctaat aatgctactg ataacaattt cttaatcttt ggatttctta
     8161 gtttcataaa atacctccat tttaaattag ttatatatca aagatatata ttattattgt
     8221 agaatataat tcttaagaat taactacatt aaatattaat aaaaaatata gtaaaactta
     8281 agaatacata taataaaact taatataaat taagtatatg aaataaatat cctgtattta
     8341 agcttataga ttataatgaa atataataca tattataata ataaaacgaa ctaaaattat
     8401 cacactaaag cataaaacat actctaatca tgttagataa atttttgaat atataatcca
     8461 aaagtactct ctaaagtaga gtacttcttt tttattaatt atttttatat ggaataaatt
     8521 ggaatattat atttgttcca atctgattga ttacatacta ttattagtat aaaatttaat
     8581 tatacataaa ttggtaagag gtgtaaacta atgaagatta ataaattacc acatgcagaa
     8641 ctaaaactaa tgaagtatat ttggggagca gatgatgtat tagcctcaag agatatcata
     8701 gaagcaatga agttgaaata cgattggaaa aagagcacaa cattgacatt tttaaaaact
     8761 ttagtagata agggattttt aactacttat taaggtagat agatgtacgc attatactat
     8821 agctataaaa gagaaagatt acttaaaagt tgagacaaag agttttttta gttttatgca
     8881 taacaattca tttaagagtt ttatttcagc actacatgat gatgaagttt tagatagtaa
     8941 gagcttggac aaattagaag aatactttaa aaatttgaaa gaagaagata ttgatgacta
     9001 ataaagctat cagtatcttt ttagtttgag acaattgaga gtagcgtttg gatttaatgt
     9061 tagttttatg tgatggtaaa acattatata aagaaaagtg attatttcct tagtgtttga
     9121 tagtaaaaaa tatagagaat aataccaatt aaaatttaaa gatatatgaa atactacaat
     9181 agcttaaatc atgtaaatat gataaagata ttgaaattat aaaaggaata taattttaga
     9241 agaaatagtt gacagataaa ttaccttact atattattgt attaataaaa taatacaata
     9301 atatagtaag gaggtaataa atgaaatcta gaaaacataa tattacaaaa ggattattta
     9361 tagtttacat aattatttta acatggataa tactatttaa gttgcaattt gatatctcat
     9421 ctcttgaaac catgaatctt agaagcataa acttagtacc ttttgctggg tcacttataa
     9481 ttaataatag agtagatata tcagagatta tattaaatgt ggctatattt gtaccatttg
     9541 ggatatatgt gtgtatgcta aaagaagaat ggagctttat aaaaaaagtt atacctattt
     9601 ttataactag tttagcattt gaaacacttc agtatatatt tgcactaggt gcaagtgata
     9661 taaccgattt gataggaaac acactaggag gaatcatagg aatagctgtt tttatgctat
     9721 tatcgaaaat atttaagaat aataccataa aaattatcaa tgtattggca ttgattgtga
     9781 caattattgt tgtattattt ttaggattag ttatttttgc aaacttatag aaataagtat
     9841 ataggtttag cttaaaatag aacgtaagat acagttacat ataaaattat ttacacataa
     9901 aaagcaccta tataggtgct ttcctaaatt attaaagaat tattgtatct tgaaactctc
     9961 gtatgttcaa ttcttgattt tctcttgttt tttctaataa atctaatgca caatttatac
    10021 aaactttaat ttctgcattg gtatttttct cataataagt tatatattta tttctatatt
    10081 tatctatttc ttttccacaa cgactacaca ttacaattac gctcatatct tagttcctcc
    10141 atctctaatt attcttaata tattcaatag tatcactttt ctgaaaataa tgattgttaa
    10201 aactgtatca aatttagatt tactttttat tataatgcat tttaataaaa aaataaaggt
    10261 tatgggtaaa atatttatag aaaaaagtat attattgaat agattataaa attttattat
    10321 ttttcatcag tcttaaatac acattaatat ctataaaatg acaaaataaa aaatactatt
    10381 taaatagaga ttaaaaaatt gatgcgaagt atttgtttgc tatatgaata acaatttatt
    10441 tagaagtttt gatttgacac tgtataataa taaagtaatt gctaaaaaag tttgatgatt
    10501 tggatgtatt tttagaaatt agaaaaatat atacttactg actaatgata atcttatata
    10561 tattttagtt tgagtgattt aagaaaagtg ttttgaaagg ggattatttt atagaataaa
    10621 tatatatata tagtagaaaa ttacatataa agagtagtat ttatttcatt accttcttta
    10681 tctgttccga tggggtcttg tagagatact tgagttttat tttttttgtt agatctaata
    10741 ttcattaaaa tctcattttc aatacatcta gaagcatatg ttgctaatcg agttccctta
    10801 tctatgttat aagtttctat agctttaatt aatcctattg tacctatgga tattaaatca
    10861 tcctgatctt ccgttgaatt attatatttc tttgctatat aagctactaa tctcatgttt
    10921 ctttcaatta atgtatcttt tgcactttta tcgttttcta ttttaaattt agttaaatac
    10981 tcaatctctt cttcaggggt taagggtttt tcaaaagatt taagagctgc caataggtca
    11041 cccccttttc aacggtcact ttaaattata tgaaggagac ttatccaagt tgactgttat
    11101 ctaataaaat aatatgcata tttttagaat ttaaaacata tatttgcaaa cttttgaatg
    11161 gaatatgaca taaagagtgg gaatttaaat ttaagttttt gttgtatata tatgaaacaa
    11221 ggcgaagaaa ttattgattt ataaagtata aattggaatt gaggtgtcaa taaatataaa
    11281 aggaaatagt atttatatat gttttggtgt tgaggtaaaa gattaatgca aagcattaga
    11341 gtctataaaa atatgaatat aggaggtgta attttacaat acttaaaaaa gtaaatgtaa
    11401 ttaattgttt gtataaagtt gattacaagc aaaaagtatc agtcatagtt aattctgtta
    11461 aggatgaagg tggtgtgtta atttatatat gtatgggaag aaattttgat tacaatgaaa
    11521 aaacttacaa aagatattta tgaaaaaact tatagttaaa tgtttatata taaaatatta
    11581 tttaggggtt gtttttatta ttgaaaataa gaaagagtgg ttttatatca atcgaatgta
    11641 taataagtat tgctatatta tatgtggctg tttatttagt ttctacatca ttgtataatt
    11701 gttatagttt tatcagtaga aatatatctg acagagaaat gttaagtaca gcaaaaaaat
    11761 atatagaaga tgagaagtat agaatacaaa atagtaagta tgagttaatt gaagataaga
    11821 tagaaaaaaa ttacataaat ggatatgaaa ttaacagtag aatagagcaa attttagatt
    11881 attatcaatg ctatgaaata aatatagaga taaaaaatga atttaaaaaa ctgaggttta
    11941 atagctatgt tactagaaaa taaaggctct atattaataa taacattgat aatattttct
    12001 attataagta ctgtgtgcat tatgtgtata ggtttaattt atacacataa taatatgttt
    12061 gagttaggat acaaggacat tcaactaaaa gaaatttctt taagtggaat agaaatatca
    12121 gtaagtaatg tactttcttg tgttgaggaa gctattgatg tatctaataa tgaagacgaa
    12181 tttagagaat atttcttagg aaataatatg attgaatgta taaaaaaaat aaaagataca
    12241 tcttatagta gtttagaaga actttcttta aaagtagaaa ataatactat ttatgacaga
    12301 ggagattttt ttgaatttga tatagaaagt aatgttagag aaaaagaatt tttaaaagca
    12361 ataaaagtaa gagtgaaaat caaaaatcca tggataggaa ttgacattga agattatatg
    12421 gataaatcta ataacaataa aattgatgac aaaacattca ataattataa agcatctgaa
    12481 aataatgaaa ttctaaatca atttaaaaat gaaagtgaaa atataaggaa tcaagaggtt
    12541 gttgaattta cagaagaaga tgaagaatat gaagaagaac ttaaacaaaa cataattgaa
    12601 aatataaaga agaattttga tgaaaaaaaa ctagtacagg tatataagta taggggtgta
    12661 taactttgaa aaaagaagga atgtgactgt aatagaatta atagtatcta tcagtataat
    12721 actcttgata gttacattat cttttccaaa agataatctt gaaaatcata aaataaattt
    12781 atttgcacgt caactttgtt cagatataag gtatgttagg cgaattaata tgtttagcaa
    12841 ctacaataca tatatatatt atataaatca aggtaaacac gaaggttatg tattgagaaa
    12901 agatggtaaa aacattaaat caataatgct acctaaaaat gcaaaaatag ctagaagtat
    12961 tgaaataata aagtttaaat ctgatgggtc gcctcaaaag gcgtctacaa tagagatata
    13021 taataataga ttaagaaaaa ctataacaat aacacctgta agtggaagag tacttctgaa
    13081 agagggaaaa tatgaaacat aaatatggtt acttgctttt ggaaagtgta gtatcattgt
    13141 cttcaatggt gataattata ctagttttat attctatatt tttgtctaca ataaacttaa
    13201 agttaaaagt agaagataag atagaactac aacaacaaag tcttgaaatc ataaaatcta
    13261 tggaaggaat tattagcaat tctatgggaa taatgaatgt atctaattat gaagaaacat
    13321 ttaaaaagac aacgtctata aaatgtagat atgtagatga aaataataat gaagaaagca
    13381 taagtaataa agaaattata ttgaatgaaa gacgaaataa gttatttgta aattctttaa
    13441 atggcgaaag tagtcaagca ggtggttatg aaattggaga ttatgtagat gagatgtatg
    13501 tattaattac taataatggt caatatgtta atattaaatt gaaattatca aaacgtagtc
    13561 aaaaatatga gactgatttc aaaataaaag tatggaattt tagtgaaagt atataaaaat
    13621 acataaattt aagataaaga aatgacatca ataagtcata taaaatataa ttattgagaa
    13681 ctatataact aaataatatc aatatgtaaa gtgtatagat taagaatata gaggataata
    13741 ataaaaatat agaataagta atttgccaaa tacttgttta tattgtataa cttatgatat
    13801 tatgatatta gtaaaaattt gtaatcctga cttgacagaa ttcaagtaag agatataatt
    13861 ttaaaggcat agtaatgtaa aatttactaa aaaataagaa atttatttta atatggagga
    13921 acaaaaaatg gtatcagcag gtgattttag aaaaggtgtt acatttgaaa aagatggaca
    13981 accatgttta gtagttgatt ttcaacacgt taagccaggt aaaggagctg ctttcgttag
    14041 aactaaatac aaaaacttaa aaacaggagc tataagagaa gaaagtttca atccaagtga
    14101 aaaattccct aaggctgtta tagatacaag acaaatgcaa tatctataca atgatggtga
    14161 gttatattat tttatggatc aagaaaattt tgaacaaata ccattaaact atgagcaagt
    14221 tgaagatgca attaagttct taaaagaaaa tgaagttgct acaataagat tttaccaagg
    14281 acaaccattc caagtggaag cgccaaactt tgcagagcta gaagttacag atacagagcc
    14341 aggtataaaa ggtgatacag caagtaatgt aactaaagca gctacagttg aaactggagc
    14401 agttgttcaa gttccattat ttataaatac tggagataaa gtaaagatag atactagaac
    14461 aggtgaatat ttatcaagag tataaaaatt tatgtatata aaagcttata tgtcttaata
    14521 atataagata tatgagcttt tagtttatat ataaaaaaga aagcgagggg tgttacatga
    14581 aacatttata tgaagaagtt gcatacttaa aaggcctagc agaaggacta gaaataagtg
    14641 ctgaaagtaa agaagggaaa atgatacata aaatagttga tgcattagaa gtatttgcag
    14701 atgctattgt aacattggat gaagaacaag aagaacttca agattttgtt gaatctatag
    14761 atgaagattt agcagattta gaagaagata ttgctgacat ggaagaagat ctttatgaag
    14821 aagatgacga tgaggatgat gaggacttca gctatataga aatggaatgc ccaaattgtg
    14881 gagagttagt agaaatagac gaagatttgt tatatgatga tgaagtagat gttgtttgtc
    14941 ctgattgtaa ggctgtgata ttatcatcag aagatgattg tgatgatgat tgtacatgtg
    15001 gtggttgtcc aagttgtgat gatagagagt aaaaattcat aagaattaaa actgcctatg
    15061 atgcctatga gatattttgc ttcataggta gttttatttt tatgaggaag ggtattatgt
    15121 attttggttt tgcaatactt ggacaaaaat agtacactag aatttataga ataggatttt
    15181 ggagggatgt aaatatgaaa ataagtaaaa aattactaga taatatacaa agatttgaaa
    15241 atgttataaa ttataaattt aaaaataaag aatatatact agaagctctt actcatagtt
    15301 catattctaa tgaaaataaa aaatataatt ttaacgaaag gttggaattt ttaggggatt
    15361 cggttttagg catagtgata agtgattatt tatttaatga agaagctaat ctgcccgaag
    15421 gggaactaac taaacttaga gcaaatatag tttgtgaaga ttcgttaagt gaagtagcta
    15481 atgatataaa tttaggtatt catatgttat taggtagagg agaagaagca acaggaggaa
    15541 gacataggac ttcaatatta gcagacgcat ttgaagctgt aatagctgct atatatcttg
    15601 atggaggttt tgaaagtgca agacagttta tacttcatca tatggaaaat ataatttatg
    15661 attcaagaaa aggaaatata tttagagact acaaaacgca tcttcaagaa gtgttacaag
    15721 ggaatggaga aaataatatc tggtacaggc ttatagaaga aaaaggacca gaccataata
    15781 aaagatttgt aatggaagtt ggaattaatg acgatgtatt gggtatagga gaaggaaaga
    15841 gtaaaaaaga agctgaacag ttagctgcta aaatagcttt aaagaaaaaa ttatgggaaa
    15901 aataaatata atatgtaaaa atataaaaag aaatatttat attagaagga tgttgtagat
    15961 gaaaaagaga attataccta tatttgttcc tcacaaagga tgtcctcatg attgcatatt
    16021 ttgtaatcaa aaaaaaataa caggtgtgag tactgatgtt actagtgaag atgcaagaaa
    16081 tataattgag gaatgtttag agactataga taaagatgca gatgtagaaa tagcattttt
    16141 tggtggtagc tttactgcta tagatattga tatacaaaaa agtttattat cagttgctaa
    16201 agaatatgta gaaaaaggtc ttgtaaaaga tattagaatg tctacaagac cagattgtat
    16261 tgatgaagat atattaagta tgctaaaaga atataagaca agtataattg aactaggagt
    16321 acaatcctta gatgaaaaag tattattaga tagtataaga ggtcatcaat ctgaaattgt
    16381 atacaagagt tcaaagatga taaaaaatag tggaatcaaa cttggattac agatgatgat
    16441 tggtcttcca gctgacacag aagaaaagtg tatatttaca gcaaaaaaat ttgtagagct
    16501 aaaaccagat tgtgttagag tctatccaac tttggtagta aaagatacag gtcttgaaaa
    16561 gttaatggaa caaaataaat ataatccatt tactcttgaa gagagtgtaa atatagtaaa
    16621 aaaagttctt gtactgtttt atgttaataa tatcaatgta ataagagttg ggcttcaagc
    16681 tactgatgat atacaaattg gaaaagctgt tttagcagga ccatatcatc ctgcatttag
    16741 agagttggta gaagcagata tgataaaaga ttatttagaa tttgttattt tgcaaaataa
    16801 aaatataaag caaatgttgg tcaaatctaa taaaaagaat atttctaaaa tcataggaaa
    16861 taaaaaaaca aatgttaaat atatggaaga aaaatttggt gtgcttttaa aaacacaaga
    16921 atccgattta gatataaatc aattagaaat tgtgttagat gggaaaagtt taattagtgc
    16981 taatatgaga gacattcata gaaaattgta tgacatttat gacctttagt tttaataatg
    17041 aagggagaga aaagatttgt atttaaaaag actagagtta aagggattta aatcctttcc
    17101 agtaaaaaca gatattattt ttaaagaagg aataacagcc atagtaggac caaatgggag
    17161 tggaaaaagt aatatatctg atgctgtaag atgggtatta ggagaacaga gtattaagag
    17221 tcttagaggt gataaactcg aagatgtaat atttgcaggt acagatacaa aaaaacctat
    17281 gaattattgt gaagtggctc ttactattga taattctgaa aatcaattgg aattagattt
    17341 tacagaagta actataagaa gaagggctta tagaaatggt gaaagtgaat tttttctaaa
    17401 taataaaagt tgtagattaa aagatataaa agaagtcttt ttagatactg gtattggaaa
    17461 agatggttat tcaatcatag aacaaggaaa agtagatgaa atattaagta ataatccttt
    17521 aagcagaaga aaagtttttg atgaagcttg tggcatatca aaatatagat ataaaaaaca
    17581 ggaagcagaa aggaatttaa gtaatacaaa ggaaaattta gaaagaatag atgatgtata
    17641 tatagaaatt gaaaatcaat taaagcctct ttttaatcaa cagacaaagg caaaaaagta
    17701 cttggaaata agtgaaaaat taaagatact tgaagtaaat agctttataa gagaaattga
    17761 aggaatagaa aaagaattaa gtgaggttaa tgaacatcgt aaggttattg aaaaggagct
    17821 caatgaaaaa gaagaacaaa aaaatgttgt agagaaaaag caagaagata ttaataaaga
    17881 ggtagaggta ttacaagatg taattgaaaa atctgtagat tatataaatt caattaaagg
    17941 agttatatca aaaaaagagt cccaaataaa tttaattaag gaaagaataa gaaattttac
    18001 gaatgaaatt agtagaaaaa atttagaaat aaatgatata aaagagaagc taaatgaaaa
    18061 taagcaatac ataaaagaat tagaaagtaa taaattatca ggtagtgaag aactatctac
    18121 cttgcaggaa aatataaaag tattggaggc aagtaaagat aaacaaaaaa ttaagttaga
    18181 atccctaaat aatgagatag aattattgaa agaaagtata attgatatat taaataagaa
    18241 acaagagttt agtaataagc tgtccacttt aaacgcaaat aaagaaaata tgaatatcag
    18301 agatgaaaat ataaattcag agataacaga gttaaacaaa aatattgaaa taaaatcatc
    18361 tgaattagat actataaata aagaatttaa tatgcaaaat gaaaatttaa agaatgtaaa
    18421 taatagacat aaagaattat caattaattt gcaggattca attagtgaac acaataaact
    18481 agaagatgaa atacagaaaa gtaaatataa tttaaatgga tataattcaa agttaaatgt
    18541 ctatatagat atggaaaatc attatgaagg atttaataga ggagtaaaag aagtactaaa
    18601 aaataaaaat ttaaaaggag ttcatggagc attaggacaa attataaatg tacctgaaaa
    18661 atatgagaaa tctatagaag cagctcttgg tgcttatatg caaaatataa taactgataa
    18721 tgagtttagt gctaagtctg caataaacta tctaaaacag aataatttag gtagagtaac
    18781 atttcttcca ttaaatataa ttaaatcaaa taaagtaagt ctaggaaatt taaaagcaaa
    18841 tactaagttc ataggaatag caagtgattt aattacattt gatgaaaagt atagaaatat
    18901 aattgaaaat atacttggaa gaacaatact tataaataat atagatgagg gcataaaatt
    18961 tgcaaaagaa actggtcata ggtttaaaat agtaacttta gatggtgaaa tcttaaatcc
    19021 aggaggttct ttgactgggg gaagtctaaa aactaatggg aatatactat cgagaaaaag
    19081 atacattaat gaatatacag aaaagataag taatatcaag aatgaaattt cacatctaga
    19141 attaaaaaga gaatctttag acaaagatgt gaaaaatatc aaaaatgaaa ttgattcaca
    19201 tgaaagtaaa ataaaagatt tagaaaaaag tataataata aaaagtacaa gtataaagaa
    19261 tgttgaatct gaaattgaat cgttaaaagg tagtattact aaattagaaa atgagaagaa
    19321 tgatttaaat tctaatctaa attatacact tgaaaaaagc gatgatgtta gaaaagatat
    19381 ggaagagtta gatgatttat acaataaaaa taaagaaaaa attgatgcat tgaatgagga
    19441 aataaaaaga tacaatgatt tatatgataa agaaaaatct gaatttgatg aattgaactt
    19501 aagtttagtg aagaaaacag aagcttataa tagtatagtt agagatataa aaagaatatc
    19561 tggtgaaaat tgtgagctag aagaaaagaa taaacaatta gaagagtcat taaattatga
    19621 agaacatgaa ataattaaat tacaagattc tatagccact gaagaaaaag aaaaagaaaa
    19681 tttaacaaaa caactagggg atagtaatag aaatcttgaa actagaaaaa tagcaaaaga
    19741 tgatttaaaa aatagttttg atgaaattaa taaagaatta aaaactatag atagacagca
    19801 tatagagctt aaagaaagtt tatttaaagt tggtggaaga ttagaaagat taaaaactag
    19861 tcaagacaca tatataaata agttgtttga gcaatatgat atgactttag tacaagcatt
    19921 ggaaattaaa gatgaagatt tggatataga tagaaaattc ttagaaagtc taaagagaga
    19981 aataagaagt cttggaaata taaatatagg ctctataaag gaatatgagg aaataaaaga
    20041 aagatacgat ttttatagcg aacaaaagca agatttagaa gagtctatgg aagagataga
    20101 aaaacttata cacactttag aagaaaatat gaaatctgaa tttgaaatta agtttgaaga
    20161 aataagtaaa aattttaaat atgtatataa gagattattt ggtggaggtt gtggagaatt
    20221 aactatttta gataaagaaa atttattaga aagtgatata ctaataacag ctcaacctcc
    20281 agggaaaaaa atgaaaaatt taaatctatt atctggtgga gagaaagctt taacagcaat
    20341 aagtatatta tttgctatat tgattacaaa gccaacacca ttttgtatat tagatgagat
    20401 tgaagcgcca cttgatgatg caaatatatt tagatttgga gaatttttga aggatttatc
    20461 taaagagact caatttatat cagtaactca taggagagga actatggaag ctgctgatta
    20521 tatctatgga gttacaatgc aagaaaaagc catttcaaaa gttattagct taaaattaaa
    20581 agaagctcag gaaataacag atattatata acttagattg acataggagg aataacagtg
    20641 ttaaaaaaat tatttggttt tggaaaagac aaggaaaaag aaatagaaaa aaaagatgct
    20701 gaagaagaaa tagaagttga agacagtgtt gatagtttag aaaacttgga agaaaccatt
    20761 ttttcaggac ttgaagaaga agtgatagat aaagtggaag atattgaaga aaaaactgag
    20821 gaaagtgtca ataatgaagg cactgaagaa atcgaaaatt ttgaaaaaat agaagttgag
    20881 atggatagta atgcaaaaga agtagaaaat atttcaaata atgattctca agaagagata
    20941 atcgaagaat tagaaaatta tgatgaaatt gagtctaaag agatagaaga taaagaagat
    21001 aagaaagtta acttgtttga aagactaaaa caaggattga caaaagcaaa gcaaggaata
    21061 actgatagaa tagatgaagt tttaaaatca tatacaaaaa tagatgaaga attacttgaa
    21121 gatttagagg aaattttaat aacagcagat gttggtgtaa atacaactat ggatataatt
    21181 gaaagactaa gagataaaat aaagcaaaaa ggtattactg aaccaataaa ggtaagagaa
    21241 gaacttaaat ctatagttga agatattctt acaaatgaaa actctacact agatatagaa
    21301 ccagcaccat gtataatatt aatggtgggt gtaaatgggg tcggtaagac tactacaata
    21361 ggtaaactag caaatagata caaaaaagat ggtaaaaaag ttttattagc agcagcagat
    21421 acatttagag cagcagcaac agagcaatta gaaatttggg caaatagaac caatgtagac
    21481 ataataaaac atcaagaggg agcagaccct ggagctgtag tatttgatgc tataaaagct
    21541 gcaaaagcta gaaaaacaga tgtattaata tgtgatacag caggaagatt acacaataag
    21601 gctaatctta tgaatgaact tggaaaagta tttaaaatag tagatagaga atttccagaa
    21661 gcaaaacgtg aagtacttct tgtggtggat gctacaacag gtcaaaatgc agttgttcaa
    21721 gcaaagacat ttaaagaagt tgcagatata acaggtatag tacttacaaa acttgatgga
    21781 actgcaaaag gtggagtagt ccttgcagta aaatcagaag tagatgtacc tgtaaaactt
    21841 attggagttg gagaaagtgt agaagaccta caagatttca atgcaaaatc attttcagat
    21901 gcattatttg gtaactaatg ttcttttaaa aataatggtt gacaagagtg ttgttatgat
    21961 ataaaataca atagtgtaaa gtaaataacc tttacagtat actgctagga agtgtaagat
    22021 atgaatatag aaaaaatggt cgaaattgga ttgttatttg aacagtataa agaattatta
    22081 actgacaagc agaaagaaat agttgctcta tactatgaag aagattattc tttaggtgaa
    22141 attagtgaaa atctgaatgt atcaagacaa ggtgtttatg ataccttaaa gcgttcagaa
    22201 aaaatactaa gagattatga agaaaagtta cacttagtat caaagattca agagcaggaa
    22261 aaaaatatta agattataaa agataaaatt attgacatta aagaagattt attgcacaat
    22321 agagattgtg ctaatttaat ccctaagcta gaaaatatag aagatgtatg tagggagatg
    22381 ataaaatgat atttgaagga ttgtctgata aactacaagg ggcatttagt aagttaaaat
    22441 ctaaaggaaa acttacagaa gtagatgtaa aaaatgctat gagagaagtt aaacttgctc
    22501 ttcttgaggc agatgttaac tttaaagtag ttaaagattt cataaaaaaa gttcaagaga
    22561 gatgtgttgg acaagaagtt atgcaaagct taactccagc tcagcatgta atcaaaattg
    22621 taaatgaaga gcttacaagt ttaatgggag atgtacaaag taaagtaatg atttcctcaa
    22681 agcctcctac aattttaatg atggttggat tgcaaggtgc aggtaagact actacagcag
    22741 gaaaacttgg aggatatttt aaaaagcaag gtaaaaaacc tctattagta gcttgtgata
    22801 tttatagacc ggcagctata aagcaacttc aagttgttgg agaaaaattg gatatacctg
    22861 tattcaatat gggagataaa gaaaatccag taaatattgc gaaagcaggt ttaagccatg
    22921 cgattaaaaa tgctaatgat ttagttatta tagatacagc tggtagactt catatagatg
    22981 aagtacttat ggctgagtta aagtctatta aatcagaagt taagccacat gagatacttt
    23041 tggttgtaga ttctatgaca ggtcaagatg ctgtaaatgt tgcagaaagc ttcaatgagg
    23101 cacttggtgt tgatggagta gtattaacta aattggatgg agatactaga ggtggtgctg
    23161 cactttcaat aagagcagtt acacaaaagc ctataaaatt tatggggatg ggagaaaagc
    23221 tagatgatat agaacctttc cacccagata gaatggcatc aagaatatta ggtatgggag
    23281 atgtcttaag tttaatagaa aaagcacaag aaaatataga cttagagaaa gctaaagaat
    23341 tagagcaaaa aattaaaaaa caagagcttg attttgaaga tttcttacaa caaatggaac
    23401 aaatacaaaa tatgggacct cttgacaaga tacttggtat gatacctggt atgggaaatg
    23461 taaaagacca acttggagat gtagatttga atggcaaaga aatgaagaga acaaaagcca
    23521 taattcagtc aatgactaca tatgagagaa gaaacccagg agtattaaat gcttcaagaa
    23581 agaaaagaat agctaagggc agtggaacta gtgtacaaga tgtaaataga cttataaaac
    23641 aacttaatga aatgaaaaaa atgatgaaga tgtttgctgg ttcacaaaag agtatgaaga
    23701 aaaggggcgg cttaggcggt ttaccttttt ttaaataaaa tataaaaaag taaaaattat
    23761 tcggaggtga ctgtaatggc agttaaaata agattaaaaa gaatgggagc taacaaaaaa
    23821 cctttctaca gaatagtagt agctgattca agagctccaa gagatggaaa atttatagaa
    23881 gaaataggat actataatcc aatttctgaa cctaaacaag taagaataaa tgatgaaaaa
    23941 gctataaaat ggttagctac tggtgctcag ccaacagaag tagttaaaaa attacttgta
    24001 aaaaacggag taatagaaaa attcgaagct tctaaacaag caaaataatt ttttcttggc
    24061 aattagttta agtaagggct cattgctaag gttactttag gagatgaaat atatgaaaga
    24121 gctagttgta gatatagcta aggctctagt tgataatcct gactcagttg ttgttgagga
    24181 atttgaagat aatgatggta tcgtcttaaa gcttacagtt gctcaagagg atatgggtaa
    24241 ggttattggg aagcagggaa gaatagctaa agctataaga actgtcgtaa gatctgttgc
    24301 aaatagagaa aatataaaag tttctcttga gatagtataa aataggagga ttaggtataa
    24361 tgcctagtcc tttttatata aatgcgtagt ttaagatttt atgatgatat gaccacataa
    24421 gattaaattt tttaagaagg tgataacatg aaagaaaaat taactcattt taaggtaggt
    24481 caaatagtaa atacacaagg tttaaaaggt gaagtaagag tttatccact tactgatgat
    24541 atagagaggt ttgatgaatt aaaagatttc tatctgggaa aagatttaaa taataaattg
    24601 gctgttgaaa aagtaagata caaaggttct atggttataa tgaagataaa aggcatagac
    24661 agcatagaga aagcagaaaa actaaaaaat aaatttatgt atgtatctag agaagatagc
    24721 agagagcttg aagaaggcga attttttata gcagatatga ttggaatgga agttttaact
    24781 gtagatggaa aatatgtagg aatactagaa gatgttcttc aatactcagc aaatgatgtt
    24841 tatgtagtaa aaggtgaaga agataaagaa tttatgatac cagctataaa aaaatttgta
    24901 cctacaatag atattgatga aagaaaaatg attatagacc ctattaaggg aatgatagat
    24961 taggtggtaa tatgagattt catataatga cactttttcc agaaatattt aattcgtaca
    25021 tggatgaaag tataatgaag agagcagttg aaaaaggtat aattgaggtt tatatatata
    25081 atataaggga tttttctaat aataaacata aaaaagtaga tgattatcca tttggaggag
    25141 gagtggggat ggtaatgact cctcaaccta tatatgacac atataagcat ataataacaa
    25201 ctcacaatat aagtaatcca agtgtaattt atcttactcc aaaaggtaag gtatacaatc
    25261 aatctatagc aaagcagatg tctttaaaag aagatataat actattatgt ggccattatg
    25321 aaggagtaga tgagagaatc attgatttaa tagttactga tgaaatttca attggagatt
    25381 atgtattaac tgggggagag ctcccagcac ttataatgat agattctata tcaagattaa
    25441 taccaggtgt attaaaccaa gaagaatcat ttgaagaaga atcatttaaa gataacttat
    25501 tggaatatcc tcattacact agacctagag attttgaagg attaaaagta ccagaagtgc
    25561 ttttatcagg gaatcataaa aagatagatg agtggagaag agaagaatct ataaggataa
    25621 ccaaagaaag acgatttgat ttatataaaa agtctaatga aaaataaaaa tataatgaaa
    25681 aattaatata tatgtataca ataaagtacc tataaatgga attaaaaaca taaaagtgct
    25741 tgtaataact attgaagtat agtataatat aaaatgttga aaatacgggc gttcctctgt
    25801 ttacactggt cgggtagtta agaacgtcta tgatatctag gaggaagaaa gatgaatgaa
    25861 atgctaagag caattgagca agaacaatta aaaaatgaag ttcctaattt tggacctggg
    25921 gacacagtta aagtacacgt tagaattata gaaggaaaaa gagaaagaat acaagtattc
    25981 gaaggtgtag tattaaagag acaaggtgga ggagcaagag aaactttcac agttagaaaa
    26041 atgtctttca atgttggtgt agaaagaact ttcccagttc actctccaaa aatagaaaaa
    26101 atagaagtta ctagaaaagg taaagtaaga agagctaaac taaactactt aagaggtaga
    26161 gtaggtaaag ctgctaagat aaaagaagct agaaataaat aattaaaaac tttacttata
    26221 aatggggggc tgatttatca gtcctctttc tattttaatg aaaattacag caaataatta
    26281 tactagaaat aaatagaaat atttgttgaa aatatacatt atttatctat gaatttatag
    26341 cttttaaaat gaaaaataaa attggtaaat attggattat attttgtaac gatattaaaa
    26401 ataagagaac agtattatgt aaagtatgac gttaaaaaga tgacaatatt atagtttgtg
    26461 aagatagatt ttttaagtgg aattagaata taataatata atattaataa ggagtgatac
    26521 atgtgtcaaa tgaatacgaa gagtatctta tggatgacaa tctacatata aactggtatc
    26581 caggtcatat gaaaaaaact aaggagttag taaaaaataa cttaaaattg attgatgtag
    26641 taattgaact tttggatgct agaatcccgt ttagtagtaa aaatccagac atagacaggc
    26701 ttgtaggaga taagccaaga gttgtcgtac ttaataagag tgatatggca gatagggata
    26761 aattgaatca atggattgaa tactataaga aaattaatat caaagctata ccagtagata
    26821 caataaaagg tgttggtata aataatataa tcgaagaatg taaaaatgta actagagaaa
    26881 aaatgagttc tttaaaagac aaagggagaa aagaaagagc tatacgaata atgatagttg
    26941 gagttccaaa cgttggtaaa tcgtctctta taaacaaatt aacaggtaga aaaagcactc
    27001 aaactggaga taagccagga gtaacgaaag ggaaacaatg ggttagatta aagggaaatc
    27061 ttgaactttt agatacacct ggaatacttt ggcctaagtt tgaagaccaa gaagttgcat
    27121 taaatttagc atttagtaga gctataaagg atgagatttt agatactgag actttggctt
    27181 taagacttat agaaaaactt atgaaaatag aacctgagaa gttgaaagcc agatataagt
    27241 tagattgtct aggagaaact ccaattgaaa ctatggatat gattggccat aaaagagggt
    27301 ttataacagg taaaaaagaa ctagattata cacgcatagc cgcaactgta ttaaatgaat
    27361 ttagagatgg aaaaatagga aatataacat tggaagttcc agaaaacgtt aaaagataga
    27421 ttttaaaaca aaatcaaaga tttaatgtta aaaaaataaa aaagcctttt agcaaaggct
    27481 tttttatttt tttgaaatat agacaaatat ctccatataa aagtataaat taggttagaa
    27541 aacctttaaa aatattaat
//
LOCUS       DAEQJM010000050        27441 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.050, whole genome shotgun sequence.
ACCESSION   DAEQJM010000050 DAEQJM010000000
VERSION     DAEQJM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27441
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.050"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            262..2280
                     /locus_tag="KRQ43_002602"
     CDS             262..2280
                     /locus_tag="KRQ43_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH2742951.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            2793..4805
                     /locus_tag="KRQ43_002603"
     CDS             2793..4805
                     /locus_tag="KRQ43_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH2742952.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNGQDLEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TEDEIEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            5033..6946
                     /locus_tag="KRQ43_002604"
     CDS             5033..6946
                     /locus_tag="KRQ43_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742953.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTDNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEINTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEENVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLRMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            6939..9158
                     /locus_tag="KRQ43_002605"
     CDS             6939..9158
                     /locus_tag="KRQ43_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH2742954.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEIALEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLISENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            9267..10097
                     /locus_tag="KRQ43_002606"
     CDS             9267..10097
                     /locus_tag="KRQ43_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBH2742955.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            10087..13554
                     /gene="addB"
                     /locus_tag="KRQ43_002607"
     CDS             10087..13554
                     /gene="addB"
                     /locus_tag="KRQ43_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HBH2742956.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIEN
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDDYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGDNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSTICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13554..17381
                     /gene="addA"
                     /locus_tag="KRQ43_002608"
     CDS             13554..17381
                     /gene="addA"
                     /locus_tag="KRQ43_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBH2742957.1"
                     /translation="MSSPKWTKEQLEVIGSRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIANISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDIDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNETESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDSPDSDY
                     YSEIEKKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17427..18638
                     /locus_tag="KRQ43_002609"
     CDS             17427..18638
                     /locus_tag="KRQ43_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBH2742958.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVIATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18625..22152
                     /locus_tag="KRQ43_002610"
     CDS             18625..22152
                     /locus_tag="KRQ43_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2742959.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNIQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFVVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKDLKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRS
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVINITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            22283..23536
                     /locus_tag="KRQ43_002611"
     CDS             22283..23536
                     /locus_tag="KRQ43_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH2742960.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            23685..24736
                     /gene="ytvI"
                     /locus_tag="KRQ43_002612"
                     /pseudo
     CDS             23685..24736
                     /gene="ytvI"
                     /locus_tag="KRQ43_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
     gene            24827..26053
                     /gene="pepT"
                     /locus_tag="KRQ43_002613"
     CDS             24827..26053
                     /gene="pepT"
                     /locus_tag="KRQ43_002613"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBH2742961.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCREKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            26260..27312
                     /locus_tag="KRQ43_002614"
     CDS             26260..27312
                     /locus_tag="KRQ43_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HBH2742962.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
BASE COUNT        11679 a         2670 c         4844 g         8248 t
ORIGIN      
        1 ttgtattaaa tttaataaac ctacaattgt tatatgtttt tatttgtctt ttatagattt
       61 ttttggcaat aaatgatata gtgaagataa ttaaatatat tcaatatatt taattttttt
      121 attttttgtt tttataattt ttttagaagt ttatttttta tgtaattatt tataattttg
      181 ggtaaaaaca ctttgatata atttcaaaaa ttaaaaggtt aaaaaacaaa gtagaaattt
      241 atgttaaata aggagattaa tatgagaaga aatacaaaat tattaacaac agggattctt
      301 tcaatggcaa tcgtcgcacc tacaatggca tttgctactg aatctaatgc tatggaaaat
      361 aacgctgatt taaatataaa cttagagaaa aaaagtatcg ttttaggtag caaatcaaaa
      421 gtcagtgtca agtttaaaga aaaaccagat gcagatagca ttacattaaa gtataaatgc
      481 tatgatatgc cattggatac aactctaaat tataatcaat caactgagtc atatgaagga
      541 actatcaatt ataataaaga cccagaatat ttaaatgttt gggaactaca agggataaca
      601 ataaacagca aaaataatcc taaaacttta aacaaacaag aactagaaaa gatgggatta
      661 aatttaaaag actataatgt aacgcaggaa tgtataattg aagatataac ttctagaaaa
      721 gatgtaaata aatatttaag aaaaacttct gcacctatta cagaacttac aggaagtgat
      781 agatacgaaa cagcagttaa aataagtaaa gaaggctgga aaaatggttc agataaggta
      841 gttataataa atggggatgt aagtatagat ggcattatat caactccact agcaactaca
      901 tataatgctc caatactttt ggttgaaaaa aataatgtac ctaatagtgt aaaatcagaa
      961 ttaaagcgtt taaatcctag agatgtaatt ataattggag atgagaatgc tatttctaaa
     1021 actactgcta atcaaattaa atcgactgta aatgctagtc aaacacgtct aaagggctct
     1081 aatagatatg agacatcttt attgatagca aaggaaatag ataaaaatca tgatgtggaa
     1141 aaagtataca taacaaatgc taatggcgga gaagtggatg cacttactat agcagcaaaa
     1201 gcaggtcaag acaagcaacc aattatatta actgataaaa atagtattac agacaacaca
     1261 tataaatggt taaagagtga ggatttacaa aatgcttatt ttataggtgg acctcaaatg
     1321 atatcaacaa atgttataaa taaggtaaat gatataacta aagataatgt tactaataat
     1381 agagtatatg gagcagatag acacgaaaca aatgcaaacg taataaaaaa attctataca
     1441 gatgatgagt tagaggctgt tttagtagct aaatcagatg tacttgttga tgctttagca
     1501 gcaggtccat tggctgcgaa cttaaaatct ccaatactta taacaccaaa gacgtatgta
     1561 tctgcatacc ataaagataa tttagaagct aaatcagcta ataaagtata taaaatagga
     1621 ggaggattga cttctaaggt aatgaactct atagcatcat cattatctaa acacaataca
     1681 actccaacag aaccaggaaa tagtgggggt aagacagtta tgattgaccc aggacatggt
     1741 ggttcggaca ctggaacaac aggtaaacca ttagggggta ttaaagaaaa agactataca
     1801 ttaaatactt cacttgcgac aactgaatat ttacgttcaa agggattcaa tgtaataatg
     1861 acaagagaca cagataagac tttatctctt ggaaatagaa ctgctttatc taactctttg
     1921 agaccagatt tatttacgag tatacactat aatgcatctg atacaactgg gaatggtgta
     1981 gaagtatttt ataagcttaa agataaagat ggagggacta ctaaaactgt agctacaaat
     2041 atattaaata gaatcttaga gaaatttaat ctaaaaaata gaggtgcaaa aacaagaaca
     2101 ctatcaactg accctacaaa agattattta tatgttttaa gaaataatga tatgccagct
     2161 gtacttgtag aatgtgcatt tttggataat gagaaagata tgagtttact taatacatca
     2221 aataaagtaa aagaaatggg tacacaaata ggtaaaggca tagaagattc attaaaatag
     2281 tctacaatga gagcatagaa aaatttaaaa taaattaatc tgcaatttta aatttaaact
     2341 aaagctataa gataagaatg taattataat agtaataaag actgtatata cattgtgcat
     2401 ataagtgcga aatgaggtat atacagtctt tttatgatta attgtaaaag gatttatatt
     2461 atatgaagaa tttacatatc ttaaggctac agttaattgt caagagttgg agtattcatt
     2521 tgtaatacac aataaaagct taattactat attttattgt gtgtttgtgt gtttgtgtgt
     2581 tttttgtgga tttttatgtc aataaatgat atagtataga taattaaatg tattaaatat
     2641 atttaatttt tttatttttt gagttttata agtttatttt tatatattac ttatatatta
     2701 tttatatttt gggttagata cactttgaca tattttcaaa agttaaaaga ttaaaaataa
     2761 agtagaaatt tatgttaagt aaggagatta atatgagaag aaatacaaaa ttattaacaa
     2821 cagggattct ttcaatggca atcgtcgcac ctacaatggc atttgctact gaatctaatg
     2881 ctatggaaaa taacgctgat ttaaatataa acttagagaa aaaaagtatc gttttaggta
     2941 gcaaatcaaa agttagtgtc aaatttaaag aaaaaccaga tgcagatagc attacattaa
     3001 agtataaatg ctatgacatg ccattggata caactctaaa ttacaatcaa tcaactgggg
     3061 catatgaagg aactatcaat tataaccaag acccagaata tctaaatgtt tgggaactac
     3121 aagggataac aataaacagc aaaaataatc ctaaaacttt aaacggacaa gacctagaaa
     3181 agatgggatt aaatttaaaa gactataatg taacacagga atgtataatt gaagacataa
     3241 cttctagaaa agatgtaaat aaatatttga gaaaaacttc tgcacctatt acagaactta
     3301 caggaagtga tagatatgaa acagcagtta aaataagtaa agagggctgg aaaaatggtt
     3361 cagataaagt agttataata aatggagatg taagtataga tggcattata tcaactccgc
     3421 tggcaaccac atataatgct ccaatacttt tggttgaaaa aaacaatgtg cctaatagtg
     3481 taaaatcaga attaaagcgc ctaaacccta aagatataat tataattgga gatgagaatg
     3541 ctatttctaa aactactgct aatcaaatta aatcgactgt aaatgctagt caaacacgtt
     3601 taaatggttc taatagatat gagacatctt tattgatagc aaaggaaata gataaaaatc
     3661 atgatgtgga aaaagtatac ataacaaatg ctaatggcgg agaagtggat gcacttacta
     3721 tagcagcaaa agcaggtcaa gacaagcaac caattatatt aactgataaa gatagtatta
     3781 cagacaatac atataaatgg ttaaagagtg aggatttaca aaatgcttat tttataggtg
     3841 gtcctcaaat gatatcaaca aatgttataa ataaggtaaa tggaataact aaggatagtg
     3901 ttactaataa tagagtatac ggagcagata gacacgaaac aaatgcaaat gtaataaaaa
     3961 aattctatac agaggatgag atagaggctg ttttagtagc taaatcagat gtacttgttg
     4021 atgctttagc agcaggtcca ttggctgcga acttaaaatc tccaatactt ataacaccaa
     4081 agacgtatgt atctgcatac cataaagata atttagaagc taaatcagct aataaagtat
     4141 acaaaatagg tggaggattg acttctaagg taatgagctc tatagcatca tcattatcta
     4201 aacacaatac gactccaaca gaaccaggaa atagtggggg caagacagtt atgattgacc
     4261 cagggcatgg tggttcagca cctggaaatt catctggagg aatgattgaa aaagattaca
     4321 atttaaatac ttcacttgca acaactgaat atttacgttc aaagggattc aatgtaataa
     4381 tgacaagaga cacagataag actttatctc ttggaaatag aactgctcta tctaattcat
     4441 tgaaaccaga tttatttaca agtatacatt ataatggctc aactaataaa caaggtcatg
     4501 gtgtagaagt attttataag cttaaagata aaaatggggg gactactaaa actgtagcta
     4561 ccaatatatt aaatagaatt ttagagaaat ttaaacttac aaatagaggt ataaaaacaa
     4621 gagtacttcc tagtgattct acaaaagatt atttatacgt tttaagaagt aatgatatgc
     4681 cagctgtact tgtagaatgt gcatttttgg ataatgaaaa tgatatgagt ttaataaact
     4741 catctgcaaa agtaaaagaa atgggtacac aaataggtaa aggaatagaa gattcattaa
     4801 aataaatgga aataaaaata tttaaaaact taatgtaaat ttatactaaa gtcaaaaaat
     4861 gaaatataag tgtatcaata gtaagactgt atgtacattt gcacatgtga atgcaagtat
     4921 atatacagtc tttttttgta gttaaatgca ataatttgat tgtgttttgt aaaatacaca
     4981 atatgatata attagataat atacacttaa tttaattgag gaaggtgatt atatggaata
     5041 tttatttgaa aaaagtagtt taaaagaata tggaaatgaa gctttagata aatatagaga
     5101 attattagat aaaactgata ataattcaag gtgtattctt ttattagtac caaacaataa
     5161 cacaaagata cgatatgaaa gggctctaag attaaattat agtgaagaac tgaaaataac
     5221 aacatatata agttttgtga agaaagaatt agttaaatac tggccactaa taatagaaaa
     5281 atgtgatgaa ataaatacaa aggttgtatc tccaacattt atatcaaata gtttaagtga
     5341 atatttaata gtgcaaaaag ttaaggaaaa aaggatacaa gaaggatatt ttgaagatat
     5401 tacaggaacc aataaatcca tagcaaatag tataatgact aacataaata aatctgcatt
     5461 taatttaatt gattttgatt ttattggaga aaaaatatat tcatcaaaga aaaataaaga
     5521 tagtatatat agattttcat acactcagat ggatgaaatt atatcatatt atataaattc
     5581 gttactatca aattcaattt tagataatgc attaagcata tatttataca atcaatacct
     5641 acttaatgat gatttttatt taaaaaactt atttacagaa gtgagatata taattgtgga
     5701 tagtcttgaa agctcaagta atgcagaagt tgattttata acagaagcat tggataatac
     5761 attacaaagt tatatatatt ttgattatag tagggattat tctgtattta ataatgtgga
     5821 tatagactat ataaatgaga aaataatatc aaaaattaag cctaaagaag aaaatattaa
     5881 aaagaaggag attagaatag aagatttata cttattacct gcaaatatag aattaaatca
     5941 atcaagtcaa ttatacaatg aaatgttaga tttaataagt gaaaaagtta tatctcttat
     6001 agaagaaaat gtatctccaa gagatatagc aattatatct cctataaaca atagtatatt
     6061 ggagcatcaa attagagatt ctttgataga aaaaaatata gatgttttta gtactaagaa
     6121 ggataaaaaa gctgtagatt atccatatgg gaatgcattg gtagtggcta catgtatatt
     6181 ttatggatat ttagatttta taaaagatga tgaatactta agctttttag aaactctttt
     6241 agaaataaat aggataaaag catttaagat ttttaatgaa acaagacatt taagtattga
     6301 taatatagat gaacatagtc agtatcgtga tattttacag tatattgaag aaaaaaagaa
     6361 gagtgatata aaaatacatg aatttttaac tcaattttac atagataaaa tgttaaattt
     6421 aaaagaaggt aaaaagaatg ttgggttatg taaaaagata atagctgaaa gtgagtcttt
     6481 tagtgaaagt ttaagtctac ttaggatgaa aaaagaaaag atatttatag aagctttaaa
     6541 aagtacaata aacgattatt actctgttgt cgatatagaa gagttgaaat ccaaagacaa
     6601 aatagtaata actactcctt attcatatat atcatcaaat atagatagaa gtatacaaat
     6661 atgggtagat ataggaagta atgcttggaa tatgaaaata gaaaaagata taagtaattt
     6721 aattgtactt agaaaatctt ttgaagaaaa aaagatttat acaaatgaaa tggaagaata
     6781 ttataaaaaa tattatctat acaatacagt atataatttg ttattaaatg caaagaaaat
     6841 ctatgcattt aaaagtgaat atgcgattaa tggttatatc caagagagta tattatatag
     6901 tatactttta aaaatctcac ataaaggaga taaaaattat gattaatata aattatagag
     6961 aagaccagat accaataata aattacgata atggtactat ggcagtacca gcagtaccag
     7021 gtgctggaaa aacatttata ataacaaatt tagtagctaa actattactt gaacagaaac
     7081 ataagggtgg taaaatatta attcttacat atatgaatag tgctgtaaat aattttaaag
     7141 gtagaataag aaagattctt gaagagaata aaatagatga tactaattcg tatgaagtaa
     7201 tgactataca cagtttggct gtaaaaataa taaaggaaaa gccagaagtt gtaatgttaa
     7261 gtgaggattt taacatagct gacgatttgc aaaaaagtat tatattaaat gaatgtataa
     7321 gtagatttag atttgaaggt ggagaaagag cttttagatg gtttttaaag gagcaaaaag
     7381 atgaacgctg gaaagaaata gctcttgaag cctgggaaag aggttttttt gaatttgcag
     7441 gaaatgcaat aagtgaactt aagtataagg gaatttctcc agataaactt gaagaaatat
     7501 tgtcaagagg acacaaagga atgcttaaaa ttattttacc aatatataaa ttgtatgata
     7561 gaaaattaaa gcaaaatgga ttgctagatt atgatgatat attaatttta gcagaaaaaa
     7621 ctttaagctt agacgaaggg cttagaaaga agtttcaaac tagatacaaa tatatatttg
     7681 aagatgagtg tcaggactca aatgaaattc aaggtaatat aataaaaatt atatctagtg
     7741 aaaataaaaa cctagttaga gttggagata taaatcagag tataacagga acattttcat
     7801 catcagaccc taaatttttt aaagaattta taaatagtgc agatttctgt tataggatgg
     7861 atatgtcaaa tcgaagttca aaagatatac ttgatttagc aaacactctt gtcaagtatg
     7921 ttacaaagga atttagacaa gaagaatgta gacatgctct tgaagatatg caaataaaaa
     7981 ctgtgccaaa tggaatggga tataaagaaa atcctaatcc agaacattat aatataaatg
     8041 taaagtggta tgagagttgg aaaattgaaa tagagcaaac tgctagatac gttaagggta
     8101 taaaaaataa atatccagat aaaagtatag gtatattggt tccatttaat gaacaagtga
     8161 cacaagttgc taaagaactt agagagaata atctaacctt tgaagaatta ggaccaaatt
     8221 ctttgaataa aaggaaggtt ataaacaaca tagcatatat tattgatttt atgttacatt
     8281 gtgatgatgt agaaaagtta atagttgtac ttaataaagt ttttatagat actgataatg
     8341 aagaagaaat aaagtatttt ttagaagaat taaaaaacta ttctaccgaa gaaattattt
     8401 ataattttga atttagtaag ttagataatg atttaataga atttaaagaa gaaagtgaca
     8461 tatatttaag ttttaaaaga ggaatagata ttataaaaca gatattagaa tatccaataa
     8521 taaggttaga cctcttagtt ttgtttattg ggaaaaaact taatttagaa aaagaagata
     8581 aagctgtact ggattatata tctttttata taaagtatct aatatcagaa aatataaata
     8641 tggatttaga agatgtatat aatttattgt ttgatgtaaa gaatagggtg tttaatcata
     8701 taatagatgt ggtatatgag ataaatggat atgaaccaga gcccggtagt ataacactat
     8761 gtaactatca taagtcaaag gggatggaat gggattgtgt gtttttacta ggtcttgttg
     8821 aatataattt ccctgacaat attaatcaaa agtttcagag tgataaatgg tatctaaaag
     8881 aaaaatataa aaaccctatg gcaattatta aatcagaagt tgaagctata ttaaaaggaa
     8941 gtatttcaac agattatgct cataaaacga agattgattc tataaatgaa aagattagac
     9001 ttttatatgt agggattact agagcaaagg aaatgttagt actttcagga agtgcttata
     9061 gagatgaaag tgatataggg aataagagaa aagagcaaaa accatgtata tatttaagca
     9121 gacttaatca acatattatt gaaaaaaggt caaattaata tataataagt tattaaaaga
     9181 ttgcttgaaa tatatctaaa aggggataaa acaatatgta cagtaagtaa ctactaaaaa
     9241 ataaagttaa gagagaagtg atatgagtga acgataaatt aaaatatttt tcttatagtc
     9301 aaaattcaat caacacatat aaatcatgtc cattgaaatt taaatataaa tatattgata
     9361 gaataaattg gaaaaatgat gatgttggta gtagagagta ttatgaaact ttaaaaacag
     9421 gaagagattt tcatttgatt tgtgaaagat attttagcaa tatacctctt ggaatctatt
     9481 ttaatgagga tgataaaaat agtaaaaagt ttttaaagtg gatggaaaat ataaaaaaag
     9541 ttgttcctat tgaaaaagga aaaacgtatt tgccagaata tgaagtaagg atgaccttaa
     9601 atggggatat aatacaggca aagtatgatt tagttgtaat tggaaataac aatatagaaa
     9661 tatgggattg gaaaaccgag tctaaaaaga ttgactataa acacgtagaa aatagaatac
     9721 aaactattgt ttatatgttt ttagcaaaag aagtaatacc taaagtttta aaaatggaca
     9781 taaatgttaa agatataaat atgagatatt atcaacctga atttgatgac ttaccaatta
     9841 ccattttata tgatgaagaa aaacatgaag caaatagaaa taaaattcaa aattatataa
     9901 gtatgataaa aaacactaat tatgaagaac atacatacga agacaatcta tacaatgata
     9961 tagaaaaggt atataataaa gaagaacgta tgtgctatag aaataaaaag cattgcaagt
    10021 attgtgaatt taataagtta tgtaatggca aagaaataga ttatagtatt ttggaggcgg
    10081 aaatttatgg gacttaggtt tgtattaggt agaagtggaa gtggaaaatc cacctatata
    10141 ctagatgaga ttaaaaaaga agctcaaaaa aatgaaacga catcaattat acttttagtt
    10201 ccagaacagt acacatttga ggctgaaaat agagtaagta agctattctt aggaaaagaa
    10261 aaagataagt atctaagagt tagggtactt agctttaaga cactaagtaa tatagttttt
    10321 tctcaagtag gaggattgac agatgtaaat ataaattcta gtggaaaagc aatgatggta
    10381 tatagagcta ttgaagatgt aagtgaagaa ttaaatgtgt tttcaaaatc aaaatcgcag
    10441 tctggttttg taagctcaat tacagatatg atatcagaaa tgaaacaata caatataagc
    10501 cctgaaatgt tagaaaatat atctggagaa ttggataatg aaactttaag tttaaaatta
    10561 aaagatataa gtaaaatata taattctttt gaagggaaat tgcatgaaaa ttatgtagat
    10621 gctcaagata tgttaacttc attggcaagt aaaattgaat taagcagtta tttagatgga
    10681 gcttgtgttt atatagatga atttacaggt tttacaccaa atcagtacaa tgtcataaag
    10741 agtatattaa ataagtctaa aagtgttaat atctctttga ctgtagatga tatcaactat
    10801 attgggtaca gtaaatctga tatgttttct agaacgaaat ttacttattc aaaattgact
    10861 caattgtgca acgaagaagg cataaaaata ttgccacaag taaatttaaa cacaggtgtt
    10921 ataaaaagat ttgaaaaagt taaggaatta cagcacctag aaagatttta taatgcttat
    10981 ccatataaaa tatattcaaa tccaactgaa aatataaaga taaaagagtt taacaattta
    11041 tattcagagg tggaagagat agccagagaa attgtacatt tagttagaga taagaatgta
    11101 agatatagag atataaccat tgctacaaga gatttaaata gatatgattt tttagtacac
    11161 tctatattta atgaatataa tataccaaac tttatagata agaagagaga ggcaaaaagt
    11221 aatccaatag ttattttaat tatttcagct ttagaaatga agaatagacg atatgggtat
    11281 gaaactatgt ttaggtattt aaaaagtgga cttataggaa ttgataatga tgatataaat
    11341 ttactagaaa attatgtgtt ggctaatggg attaaaggta aaaaatggtt tgatgaaaaa
    11401 tgggattata gaataacaca aagtctttca ggtcaagaaa gtgaatttga actggaatta
    11461 aaagaaaaaa taaatgaaat aaaaaataga gtattagagc ctatagtaat tttacaagaa
    11521 aaattaagag gaaaaaatag agtaaaagaa atctgtagat atatatatga atttttatta
    11581 gatataaata tgccagaaac tatagaaaat ttaatagtaa attttaagga taaaggggaa
    11641 cttgatgttg caaatcaata ctcacaagtt tgggacatag tagtggacat attagaccaa
    11701 atggtggaac ttatgggtga tgaaataatt tctttagaaa aatttataaa attaataacc
    11761 ttaggctttg atgaatatga attaggactg gttcctccta gtatagacca ggtacttgta
    11821 agtagtgtgg atagaatgaa aaatccagac acgaaatatt tatacctagt tggaactact
    11881 gatggtgtgt ttccactgat tacaaaggat agtggaatat tgagtgataa tgatagggaa
    11941 agtcttggaa acaaaggaat cgaagttgat attgatagta agactaggag ttttgaagaa
    12001 cagtttcttg tatataaagc tcttacttcg acatctaaga atttaaccat aacatatcca
    12061 atatcagacc atgaaggtaa aacgcttaga ccatcaataa ttatatcaag acttaagaag
    12121 atatttccaa atatagaaaa taaaagttat ttagtggaag aaaataaaag cactgataaa
    12181 gatatactta aaaaaataac ggttaaatcc cctacattta atgaacttat aaacgtaata
    12241 aaaaattatg acagtgatga ttacaataca gaagagatta atagtatttg gttagatata
    12301 tataggtact atttaaaaga tgaaatctat agttctataa caaaaaaagt tataaaaggt
    12361 cttagttata ctaatcaagt tcataagatt gaagagaaaa aaataaggtc attgtataaa
    12421 agtaattctc ttagcatatc taggcttgaa aaatatgctg aatgtccatt tgcttatttt
    12481 atacaatatg gtctaaaagc aaaaaagcgt aaagagtatt catttacacc accagattta
    12541 ggaactttta ttcataatat tttagatagg ttttcaaaag aacttttaca agataattta
    12601 acttggagag atattgatga aaaatatata gaattaaaga taggtataat agttgatgaa
    12661 ataattttaa agataccagg atatatatta aatagttctg agaggtataa ataccttgca
    12721 tatagattaa agaatatgtt gacaactgct ataactataa ttagtcagca aataaaacaa
    12781 ggttcatttg aaccaataga ttatgaagtt aaatttggcg acaatggaaa atatccacct
    12841 ataaaaatgg tgttagaaaa tggacaagaa gtaagtttaa ttggacaaat agatagagtt
    12901 gatgaatttg aagaaggaga aaataaatat ataagaataa tagattataa gtcaggcaat
    12961 aagtccataa gtctaacaga aatatattat ggtctacaat tacaattact tgtgtattta
    13021 gatgcaatcc ttgaaagtgc aaaggatgaa gatataaata taaatccagc tgcaatacta
    13081 tattgtagaa taaataatcc aatagcaaaa tttaatgaag ataaagatga tgaagaaata
    13141 caagaagcaa tattaaaaga acttagaatg aaggggcttg tagtaaaaga ctctcacata
    13201 gttaaagaga tggataaatc attaatagat ggagaaagga aaaactcttt agtaatacca
    13261 gtaggtctta ctaaggatgg aaatgtaggt aaaagtactt cagcaataag ctatgaggat
    13321 ttcaaactgc ttagaaaata tgtaaggcat gctataaagg atttatgtga agaaatgtta
    13381 agtggagaaa tacgtatagc tccatataaa cataaagatg gaacatcatg tgacttttgt
    13441 gattactcta ctatatgtca gtttgattca actataaaag ataacaagta taaaaattta
    13501 aataataaga gtaatgaaga gataataaaa atgatgaaag gagatgttaa ttagtgagtt
    13561 ctcctaaatg gacaaaagag caattagaag ttataggaag tagagaatgc aatttattgg
    13621 ttgctgctgc tgctggttca ggaaaaacag ccgttctagt tgagcgtata attcaaatga
    13681 taacaagtag agaaaatcca attgatatag ataagttatt agttgttaca tttactaatg
    13741 ctgctgcgtc agaaatgaga gagaggatag gggatgctat aggaaaagcc ttagatgaaa
    13801 acccagaaaa taaacattta caaaaccaac ttgttttatt aaataaatct agtattacaa
    13861 caatacactc attctgtttg gatgttataa aatcaaactt tcatagaata aacttagacc
    13921 ctaatttcag aataggagac caaactgaat gtgctatttt gaaacaagaa gcaatagagg
    13981 aagtatttga agatttatat gaagaaagag atgaggggtt tttaaattta gttgaaagtt
    14041 atgcagaaag aggaggagat aaagaagtac aagatattat cttgggaata tattcatttg
    14101 caatggcttc tcctgaacct aaaaaatggt tgattgactc agcagaacga tttaatattg
    14161 atgaaaattt tgatttttca cagtctattt gggctagagc tatattagac actgtaaaaa
    14221 tagaaattaa tggtctttgt ctaaatatgg aaagggcatt aaaagaagtg gaatcaatag
    14281 aagaattaga aacttttgca gaaaagttat ccgttgaata taaaaaaatt gctaacattt
    14341 cacaagcatg taataaatct tgggatgagg catataaaaa gatggcaagt atgtcctttg
    14401 aaaattatgt aaaaggagta aaaagaattt caaaagatgc tccttcgtat ataaaagaat
    14461 caaaagaaaa ggcaaaaact ataagagata agactaagaa gtctttagaa agtatagtaa
    14521 gtgctacatt caataaagat aatgattcta ttagagaaga aataaaatat ctttataaca
    14581 tagttaaacc aatatctagt gttgtactga gatttgaaga ggaatatagc aataagaaaa
    14641 gagaaaaagg aataatagat tttaacgata tagagcattt tgcattaaat atacttacag
    14701 atatagatga aaaaggtaat attgtacctt ctgatatagc cgttggatat agaaacaagt
    14761 tttatgaaat atttatagat gaatatcagg atagtaatct agtgcaggaa gtactgctta
    14821 aagctgttgc aaatacagaa actccaaata gatttatggt tggtgatgta aaacagagta
    14881 tatatagatt tagacaagca aagccagaat tatttttgca aaaatataat aactataatg
    14941 ataaaaaggg aagttcccat agaaaaataa tgctttacaa aaattttaga agtagagaag
    15001 aagttgtaga tgctgtaaat tatatatttg aaaatataat gaatgagaat ataggagaaa
    15061 ttgaatatac agaaaaagaa agactaaatt taggtgcgaa ttttaatgtg gatacagacg
    15121 agaaatctat tattggtgga gcaacggaga tacacctaat acaaaaagat aataaacttg
    15181 atgatgatat tataaatgat aaagacgata gaattaataa caaagaaaat gaaatagagg
    15241 aagaagaaaa attagataat atacaacttg aggctagaat ggttggaaac attatcaaag
    15301 atttaatgaa agtcaatgaa gatggaaaaa ttcaaaaggt ctatgataag ggaatagatg
    15361 gatatagacc tgtggaattt agagatatag ttattctttt aagagctaca tctgcatggg
    15421 ctccagtgtt tgcagatgaa ttgatgaata tggatatacc aacatatgct gatgttggag
    15481 tggggtattt tgatacgatt gaaataaaaa caatattgtc attacttcaa ataatagata
    15541 atccaatgca agatatacct cttatatctg tattaaaatc acctatattt ggatttacac
    15601 cagaggattt gattgatatt agagttcaga gtaaagataa aattttttat gaggttttaa
    15661 aaagtacagc agagtatgat ggatttacag attctcaaaa tgaaactgag tctgagttta
    15721 taccaagtga agagtgcata aacaaaagta aagatttttt aattaagcta aaggaattta
    15781 aagaaaagtc aatgtacatg agtacagatg aatttatatg gtacttgtac acaaggactg
    15841 gatactatgc ttatgttgga gcattgccag gtggaagtca aagacaagct aatttaaaag
    15901 tattgtttga gagagcaaaa caatttgaag aaaccagtct taaaggaata ttcaactttg
    15961 taaattttat agagaaatta aaaaaatcta gttctgatat gggaagtgca aaaacacttg
    16021 gtgagaatgc aaatgttgtt agaataatga gtattcataa aagtaaaggt ctagaatttc
    16081 cagtagtcat atgctctgca atgggtaaaa atttcaatac tcaagatttt aaaaagagta
    16141 ttttatatca tcataattta gggtatggac ctcaatttgt agactatgag agaaggattt
    16201 cttttccaag tatagccaaa gaagcattaa aaagcaaaat aaatatagaa aatttatcag
    16261 aagagatgag agttttatat gttgcattta caagagctaa agaaaaattg attataactg
    16321 gttctactag aaatatacaa gatagtataa agagatggtc aaatggaatt gaaagtttag
    16381 atacaatatc acaatacgag atattaaaag gtaaaaattt tttagattgg ataatgcctt
    16441 gtgtattaag acatagggat ttatctaatc tactagaaga agtaggatta gacgcagttt
    16501 ttaatgttga acataattca aaatggtatg gaaagttgtg gaataagaat gatattttag
    16561 tggaaaagaa gagtgatgaa gaaaaagaaa gtattgaaga aattcttgaa aaaatagatg
    16621 tagatagtcc ggacagtgat tattacagtg aaatagaaaa aaaattaaac tatatatatc
    16681 catatgaatt tagtacaaga aaacctgcta ctatatctgt tacagaaata aaaaagatac
    16741 aaaataatta tgaagaagag ttaataaata ctatatttga acaaaaagta atattaaaaa
    16801 agcctctatt tattcaaaat gaagaagaaa gagaaaaaat aagtggaaca gaaagaggta
    16861 caatagtcca tttggttatg gaggttttag acttaaaaaa tgtaagtagt gtaaatgata
    16921 taaaatcaca aataagaggt tttgtttcaa aaggtataat aacagaaaaa caagctagta
    16981 tagtaaatcc atataaaata tataaatttt ttgcctctaa cataggaaaa agaatgttga
    17041 atgctgaaat tataaataga gaaaaatcaa tttatgcaca agtaaatatg aaagacatat
    17101 atatttatga aaagcttata aacaatgatg ataaaaaact ttatgataat gaaagtgtca
    17161 tgttaagagg tatagttgat gcttattttg aagaagataa tcaaatagtt ttggtggatt
    17221 ataaaacaga ttttgtaaat gaggaaaata taaatcaaat aatagagaaa tataaaaaac
    17281 agttggattt atatgcagat attattgaaa ctttaactgg taagtcagta aaagagaaat
    17341 gtatatattt atttggagtt gatgaagctg tttgttatta gtttttatat ataaattaaa
    17401 cctaaaagat agaggaaggg gaaaaaatga gatttattca tacatcagat tggcatctag
    17461 ggaagtccct agaaggccat tctagaattg aggaacaagc aaagttttgt gaggaattta
    17521 taaaaatagt agaatcaaat gaaatagata tggttataat tgctggagat gtatatgata
    17581 cttctaatcc cccagcacaa gcagaaaaac tattttatca gactgtatca agacttgcca
    17641 ataatggtca gaggtgtgta ttaataattt caggaaatca tgataatcca gagagacttt
    17701 ctgcaataac acctctagca catgaacagg ggatacttat atatggttat ccattaagtg
    17761 ctacgataga agctaagtat aaagggtttg aaataacata tgcaactcag ggatgtacaa
    17821 aactgaatat aaatggagaa aatattgtga ttgctacatt accttatcca agtgaaaaaa
    17881 gattaaatga agttttttca agtgaagatg agtttgagaa acaaaaaaat tattctgaaa
    17941 aggtaggaga tatatttaga agtttagaag aaaattttag aagtgatact ataaatatag
    18001 ccgtatcaca tatatttgta ataggtggag agagtactga atcagaaaga cctatacaat
    18061 taggtggaag ttttttagtt gaaagaaaag atttgccaga aaaggctcaa tatactgcac
    18121 taggtcattt acataaacaa caaaaagctt ccgaacgttt aaatgcatac tattctggtt
    18181 ctccacttca atatagcaag gatgaaagag cgtataccaa aggggcatac atagtggata
    18241 taaaagctgg agaaaaacca ataattgaag atgtatattt taataattac aaacctatag
    18301 aagtatttaa atgtaatgga atagaagaag cactagatat atgtgagcaa aatcaagata
    18361 gagagatttg gtcatatttt gaaataaata ctgatgagat aatatcacag aatgaaatta
    18421 aaaaaatgaa ggaactatta aaagacataa tagaaataaa accaataata acatcttgtt
    18481 atgaacaaga aagtgtagat ataaaagaaa agtctatggc agagttgttt agagagttct
    18541 attcttttag taaaggtgta gagccaaaag gagaacttat ggatttattt ctagatataa
    18601 taagtgaaga aggtgaatca gcagatgaga ccaattagat tagaacttac aggacttaat
    18661 agctatattg ataaacaagt tatagacttt gaaaaattaa ttgaaagagg tttgtttggg
    18721 atatttggaa ctactggaag tggaaaatct acaatcttag atgcaataac tattgctatg
    18781 tatggaaata tatccagaaa tacaaaagaa tatataaaca gtgtgtgcga taaggcaatt
    18841 atatcatacg agtttgagat aggaagcaaa aacactagaa gaagatacat tgtagataga
    18901 accattgcta gaagcaaaac aggaacaaag acctctaatg ctagattaat agaagtattg
    18961 aatgacaata tccaaaatgt tttagctgat aaagttgtgg aagtaaatga aaaagtagca
    19021 caggttgtag gattaacggc aaatgatttt actaggtcag tagttttacc acaagacaaa
    19081 tttaatgagt ttctaagatt atcacgtgca gatagaagag acatgttaga gagaattttt
    19141 aatcttgaga aatatggaag aagtcttgga gaaaaagtga aaaagagaaa aaatatacag
    19201 ttacaaaatt taaaagattt gaaatcaaaa ttaagtcaat atgatggaat tacagaggaa
    19261 gtatacaaca atataaacca agaattaata gagttaaaaa atttggaaaa agataagaat
    19321 aatgctttag acctagctca aaaatcttat gaagaaagta aaacagtata tgaagaacaa
    19381 ttaaagttag aaaaaaatga acttagaaaa aatgagcttg atttaaaaaa tagtgagata
    19441 aaagaaaaga ttgctcttgt agaaaatgat agtaacgcta aaaaggtaga cccatacata
    19501 agttcagttc aaaatctaga aaaaaagata gatgaagata gctttgtagt aagtaattta
    19561 gaaaagaaat tagcaatatt aaatcaggag cttgaagtta caaaaaatag atatgaaaaa
    19621 ataaacaaaa ttaagaatga agaagtccct aaattgagtg aagaaaaaat aagattgcaa
    19681 caagcaataa aattagaaga agagttagtt ttattagata gagagttaaa agatctaaaa
    19741 gaaagtggaa ttaatttaaa taagactaaa gttgaattag aaaaagtaaa gcaggtgtca
    19801 gagtccagaa aagatgcagt tactaaatct ataaaagaag ttgaaggaaa gattgataaa
    19861 gtaaatataa gtgcagaatt aaaacaaaaa atatttctag catatgaata cgagaaagat
    19921 tacaacaacg tattggaaga aaaaaatcaa aagctaaata aactagaaga aatactcaaa
    19981 gagacagaaa atataaattt aaaagttaga tatattgata aagataagaa tgatgtaaat
    20041 cgtaatttag aaaatttatc acttcacttg gatgttcttc ttaaaaaatg tcctggtaag
    20101 agtgctgatt tacttttaaa atctgaatat gttactgaat taagaagtaa agcaaataat
    20161 actaaagaaa atgaaattaa gaaaagcagt atacaagatg aattaaagat aatacttgaa
    20221 agtaagttta atactgaaag ggaagtaaat ttactaaatg aaaaacttga aaataataga
    20281 aagaatagag atgacctaga aaaagaatta gaagaactaa agtatttaaa tttagcctct
    20341 gaacttagac gtgaattaaa agaaaatatg ccttgtccag tttgtgggtc aaaacatcat
    20401 gaaaatcata atataactaa gtatgatgaa aatatatctt ttgtcaaaga aaaactggag
    20461 aaattagaaa aagaaaaaat aagtataaga aacaatatag aggaattaaa tgctaaagta
    20521 agtgggtatt tatctataga aaaaatgaag actaaagaac ttgaagatgt aaaaggaaaa
    20581 ctagggggga ttccatctag tcaattatta aaaaaacttg atgaagaaca aagaaaactt
    20641 gcattgttaa aatctaatat tcaggagtgg gagaaagaaa aagagagtac tgaaaataaa
    20701 gtaacattag ctaaagaaga aaaaaataaa attgaaaaag aagaattaaa aataagagag
    20761 agtctgaata attataagaa attaacaaga gatttaaaca tagaaataga aggtttagaa
    20821 aataaatgta aaaaacttaa acaggaatac ctaggattaa agacgattac taaagtctct
    20881 aatctattgt caaaagtaaa agaaataagg gagaatgaaa aagaattaga attactaagt
    20941 actgggcatt caaatttatt aaaaaataga gactcactag atattaaaat aagagaaaat
    21001 gagagtaaac tacatgaaat agagatagaa ttaataaagg ctagagaatt atatgtagaa
    21061 aagaaattga gtagagataa taagtataaa gaagttatta acataacgaa aggtgattta
    21121 gctaaaaatc ttttacataa tgttgaagaa aatatatgta agatattaga acaagaagaa
    21181 tcaagtaaga aaaaattgga agagcaaaga ttagaatatg aaaaaaacat tgctgaaaag
    21241 cacaatatag atggtagact taaaactgct aaggaacaat ataaagacca aaaatcaaca
    21301 ctaaataaac tattagcaga aaataaattt gaaagtatat atgcagtaaa aagagcttta
    21361 ttagatactg atgcagtaaa aaaattgatt gaagaaatac tagagcatga agaagaacaa
    21421 aagttattat catttaagat aaaatcatca aaagaaaaat taaatggaag aagcataaag
    21481 aaggagtact ttgaacagtt aaaagatgaa atttataatt tgaaagtaga aataggaaat
    21541 atatccaaag atattggagc taatcaaaat cagttaataa cactaaaaga ctctttagat
    21601 aagataaatg attttaataa acaacttaag gtagttgaac acaatgtgga cttattggaa
    21661 gaattagata aatgtgtgca aggaaataaa tttgtagaat atgtttctac aaaccaatta
    21721 aaatatatag cattggaagc atcaaaacga ttggatggaa taacaaaagg aagatatgca
    21781 cttgaaattg actcaacact aaactttgta atgagagata actttaatgg aggagaaaga
    21841 agaagcattg atactctatc tggtggagag acattcttga catctctatc attagcactt
    21901 gctctttcat ctcaaataca attaaaggga agtgcaccat tagaattttt ctttttagat
    21961 gaaggttttg gttcattaga tagtgaactt ttagaaattg ttatagaatc cttggaaaga
    22021 ttgcatagta ataatctaag tgtgggtata ataagtcatg tcgaggaact taaaaataga
    22081 gttcctgtta agctattagt ttcatctagt gaggctggaa taggttcaaa agtaaaaatt
    22141 gaatatagtt agaaaatata tggtaattga atatattatc taatatttcc aaataatatg
    22201 taattgtgat ataataaaaa ctaatattaa agttatttat aattaatatt aatataaaaa
    22261 catgtaagta ggagtgtggt aagtgttgga atcgcccaat aatttgattc agattatttt
    22321 tttaatagta ttacttatag ggtctgcatt tttctcagca tctgaaacgg ccttaatgtc
    22381 gttgagtaaa atcagaatca gatatatgca agatgaagga gttaaaggag ctaagttagt
    22441 aagttcatta atagaaaatc caaataagct tttaagttct atattggttg gaaataacgt
    22501 cgtaaatata gcagcaacat ccatatcaac atctttgttt ataggattaa tgggagaaaa
    22561 aggagtggca cttgctacag ctgttatgac agtattagta ttaatatttg gtgagattac
    22621 tccaaaaaca atagcagcaa ataattcaga aaaggtttct ctattagtat ctaaacctat
    22681 aaaagcaatt atatttatat taagaccaat agtatggata tttaatataa ttacaaatat
    22741 tatatttaaa ttatttggta taacaaataa aggagctaaa tcattcataa ctgaagaaga
    22801 gctaaaaact atggtaaatg taagtcatga agaaggcgtc cttgaaatgg aagagagaga
    22861 aatcataaat aatgtttttg aatttggaga tatgcaagct aaaaatgcaa tggtacaaag
    22921 aatagatatg gtagctatag atatggaaga tagttatgat gagataatac aggtatttaa
    22981 aactgaaaaa ttaagtagaa tgcctgtgta tgaagaaact atagatgata ttgtaggaat
    23041 acttaatata aaagatatta tatttttatc tgatgaagaa atagagtcat ttgatattaa
    23101 aaattatatg agagaacctt ttttcacgta tgagttcaaa aagataacac aacttcttga
    23161 agagatgaaa cttgaaaaaa gtcagatggc tatagttgta gatgagtatg gtggaacatc
    23221 tggactttta actatagaag atttagtaga agtcattgtt ggagatatag aggatgaata
    23281 tgatgaagaa gaggatgaaa tacaagttat aaaagaagat gagtatattg tagatggaag
    23341 tactaaaatt ggtgatgtta atgaacttat tggtgtaaac ttggaatctg aggagtttga
    23401 ttccatagga ggttttataa ttggacacct aagcagattg ccagaagaaa atgaagtaat
    23461 tgaagttgat aatataagat tttgtataga aagtatagaa aaaaatagaa ttaaaaaaat
    23521 aagaatatat acataatgta ataatgttct taaatttatt agaagtgtat aaatataaaa
    23581 gatatctttt atatttatac acttcttttt attttgtatt caaataaaac tagtatgaaa
    23641 tggacaaaat aaaaatataa attagaagaa aggagatttt taagatgagc atactagaaa
    23701 ataatttttt atacaaatta aaaaacaaca ctatcttttt ttgtatatat acattgttat
    23761 ttatttttat ttacaaagcg tttccataca tagctccatt ttttctaggt gctataatag
    23821 cacttatgat taatcctata gcacaaaagt tagaaaataa gtttcgtata aataaaggta
    23881 tctctactct tgttctaagt tttcttgcag tggctatagt cagtacagtt actacaataa
    23941 tagtaataaa ttcaatgaaa gaattaatgg gatttttaaa taatatatct gctaatcctg
    24001 aggatataag taatactatt atgtattttt taaataaaat aaatgacttt atgaaatcat
    24061 ttcaagaaat agccaatttt gatgtagaac aattagtaaa caaattcagt ggtgaagtaa
    24121 tgcaaattac aaaaaatctt cttactagta tacttggatt ggctacttct attccatata
    24181 ttataatatt tataattacc ttgtttattg ctacctactt tatagcaaaa gaccttgata
    24241 agattgaaaa tagtttttat aatatgttta ctgttgatgt tagaaagaag gtaaaaaacg
    24301 taaagaaaga ggcagggctt tcacttgttg gatatataag ggcctataca atacttatgg
    24361 ctataacatt ttttgcaatc tggggaagtt ttgctttatt tggattgaaa tacggtctaa
    24421 tagtagggtt tgtagggctt taatggattt aattccattc ctaggtataa taacaatata
    24481 tcttccagta attgtttatt attttcttat aaaaaattat tttatagcta taagtatgac
    24541 tgtgatattt tttgttttgt ctttgattag agaaatactt gaacctaaac tagtatcagt
    24601 aaatgttgga ctaaatccat tagctaccct agcagcgatt tttattggaa tccaagtaaa
    24661 aggaataatt ggagtaattt tttgtttggg tttggtatgt atgcatgata tacttaagaa
    24721 ggtggatatt ttttaattat aataattgat agattttttt aaaaataaaa ttttattcac
    24781 aggtaaataa aaaaatatta atcttattaa gaaagagggt atatacgtga aacaaaaagt
    24841 agtggaaaga tttttaaaat atgtatcatt tgatacaaca tctaattctc agtgtgagaa
    24901 ctgtccatct tcagaaggtc aaagagtttt agctaagtat atagttgaag agctaaaaac
    24961 aatgggtgtt gatgatgtga gtttagatga aaatagttat ataatggcta ctttaaaagg
    25021 aaatactgat ggtgtggata ctataggatt catatcacat ttagatacaa ttgaagatgt
    25081 tagtggaaaa gatattaaac caagaataat agaaaattat gacggaaaag acatagtttt
    25141 aaatgaagcg ttaaatgtta ttacgtatgt aaaggattct ccagagttgg aagaatttaa
    25201 aggtgacgat ttaatagtca ctgatggaac aactctactt ggctctgatg ataaagctgg
    25261 tatagctgag atagtgactg caatagagta tctaataaat catccagaaa ttaagcatgg
    25321 agatataaaa ataggattta caccagatga agaaattggt agaggtgctg atttatttga
    25381 tgttgaaaaa tttggagcaa aatatgcata tactttagat ggaggaatag ttggagaact
    25441 tgaatgtgaa aattttaatg ctgcaaatgc aactattact atacatggta gaaatgttca
    25501 tccaggttca gctaaaaata aaatggtaaa tgctatacat atagctgctg aaatatcaga
    25561 aatgttccca gcagatgaaa gaccagaaac aacagaagga tatgaaggat tttggcattt
    25621 aaattctata ggtggaaatg tcgagaatgt aagtatggct tatattatta gagaccattg
    25681 tagagaaaaa tttgaaaata gaaaatctat tatgatagag aatatagaaa aaataaataa
    25741 gaaatacgat aatagagtgg aattggattt aaaagattct tattacaata tgaaagaaaa
    25801 gattgagcca gttatgttta tagttgatat agctaaagaa gctatggagg aattaggtat
    25861 aaaaccacgt ttagttcctg taagaggtgg tactgatgga gcaagattat cttttaatgg
    25921 attaccttgt ccaaatatat ttactggtgg attaaacttc catgggaaaa atgagtgtat
    25981 accagttagt tctatggaga aagctactaa actaattgta agaatagctg aaaaatatgc
    26041 tgaaagagtt tagttaaaaa gtatttaaaa attaagcatt taaagttata atagctatat
    26101 cattctttat aagtcaagct gattataagc ttgtgttgta tttaaaatgg tatagctatt
    26161 tttgtaatta tttttataaa agataattat ttttagttta gggtatcaat aaaaagtatg
    26221 gatatcaata ggtattaaca tttaaaaggg ggaattgtat tgaaaattaa atctaaaaaa
    26281 ataatagcat ttgcactttc acttgggatt atgttgccaa gttgtgtata tgcagacact
    26341 attagtaaaa atcaaaatgc acaggtagat atgaacaatt atcttcaagg tagaaaatct
    26401 ccaaaggagg aaaaacttat tggtgaagat agatttgata cagcgataaa aatatctcaa
    26461 agtggttgga ataatggttc agaaagggtg tttctagtta actcaaattc attgccagat
    26521 gcattggctt caactccttt ggcaagtaaa ttggatgcac caatactgct tacaaataaa
    26581 aatagtatac catataatgt aacagaggaa ataaaaaggc ttaatccagc agaagttatt
    26641 ttaattggaa gtgaaggagc tatttcatca agtgtaaaag aatctcttga agatatggaa
    26701 gtattagtca gtagaatcgg tggagcagat agagaagaaa catctttact tcttactaga
    26761 cagctagatg atactggtga tttaggtgtc tcaaaagtgg cagtggttaa tgggtataat
    26821 ggactggcag atgcaacttc aatatcaagc ccagctgcaa gtgataatac agctataata
    26881 tatacaggta aggatagcat aagaagtgag gcaaagaatt ttattacaca aaactcaact
    26941 aagacataca tagtaggtgg ggagtacagt ataagtaaaa aacttgaagg acagttagta
    27001 aactcagaaa gactagcagg aacagataga aaagatacta atgcgaaagt tttagaaaag
    27061 ttttatggaa aatcaagtaa ggttaataat atgtattttg caaaagatgg aagtggtaga
    27121 gaagctgatt tagttgatgg gcttgctgct ggagtattag catcaaaaac aaagtcacct
    27181 gtagtacttg caagtggaag tttaagtagt gcacagaaaa gttttataaa aaaagtaaag
    27241 gctgataaat ttgtacaagt tggtggaggt aaaaatagta aaccatatgc agaagcatta
    27301 gccttacagt aatattgtgt aaatcaaaat taatatataa taatagcaag taaaccaagt
    27361 tgaacttcaa tatatataat aaaataagta aactaagtta tatttcagta taatatataa
    27421 tgaaataagt aaactaagct a
//
LOCUS       DAEQJM010000051        26263 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.051, whole genome shotgun sequence.
ACCESSION   DAEQJM010000051 DAEQJM010000000
VERSION     DAEQJM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26263
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.051"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     repeat_region   663..1019
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=663..691
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            1258..1446
                     /locus_tag="KRQ43_002615"
     CDS             1258..1446
                     /locus_tag="KRQ43_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742963.1"
                     /translation="MKIITDSSRADYFKQRRQNKKTFSVLLDREKVEKIEEHLKKQNK
                     TKTIWLEEKINEELEKEE"
     gene            1565..2431
                     /locus_tag="KRQ43_002616"
     CDS             1565..2431
                     /locus_tag="KRQ43_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="HBH2742964.1"
                     /translation="MKNLIVKEFNGSQIYTFMWKEKSCWIANQIVGLFDYADVSKTIQ
                     DCIKAEDFEIEQEYDVLKGNEFNDFVTTLNVVANNIISNKARSITIFYEDGLYGFLQY
                     TDKPIGVQFRKWLRREVLPSIRQTGAYITNNANPEKLREKASEIEKLQLAYNSTSMLK
                     ELLDGAGFDNKSKLLTAKTLYKKAGIDLPIEINEEEHYFDTKQIASKLKIYSKSNKPA
                     QLAVCEIIKKIDLEENEVKGVWETNGSWTGTVNKYTKSVIDKVRNWIEENNRPTKIAG
                     EKKNYHVVYKIE"
     gene            3296..3823
                     /locus_tag="KRQ43_002617"
     CDS             3296..3823
                     /locus_tag="KRQ43_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBH2742965.1"
                     /translation="MREGKRRRGCLFWFILIILFSGVVGAIAGNSTNNESTEKQKEDL
                     TKYIGEEGSIGDLKLTVNSISKASEISVASGYLAYTPDSGKYGIINLTIKNQTKESQS
                     FMLNSFTLIGPDDSKYVPSLLIDVGNKYITMDTVNPNLDVTGNIAFEIPKDLLVSDCK
                     LKYSGSEQEFILKEK"
     gene            3961..4728
                     /locus_tag="KRQ43_002618"
     CDS             3961..4728
                     /locus_tag="KRQ43_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4428 domain-containing protein"
                     /protein_id="HBH2742966.1"
                     /translation="MGLFGKKKADICCICNTEIGVLNIEDGWICNSCFKEYCDALSMT
                     KAPKILRKLDIEKTISSTKKNNELQKIFNTTNNIENYIEFDEDNKKWLVSKKSINDKK
                     TPIIHSYEDIVKFELLENGETVTKGGIGRALAGGILFGEAGAIVGGITGKKTTRKVVD
                     TFKIKITINNIDNPIEYIELINKKTKTNSSAYEKAYKDAHKILSTLSAITQSIKETDN
                     INTKSVADEILKYKNLLDMEAITQDEFNTKKKELLNL"
     gene            4794..7166
                     /locus_tag="KRQ43_002619"
     CDS             4794..7166
                     /locus_tag="KRQ43_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBH2742967.1"
                     /translation="MATIQTSIKIFDGMTPAFRNMTTSINTTINSLERLQQRLHNPLN
                     TGGIQASQQSLNNIENILTRIEQKIGRNTNEQENFNNKIKQGSEAGSLLVSKLKSLAG
                     IYIGIRGIESITKAADTIASTKARLNLMNDGLQTTEQLNKMIYLSAQSARASYADTAA
                     QVAKLGILAGDAFGSSAEVIKFTELMNKAFVIGGTSANEASAAMYQLTQAMGAGKLQG
                     DEFRSIMENAPLLATKIADAMGKTKDQLKELSSSGAITADVIRNALFKASDEIEKKFA
                     SMPVTFSQALTMMKNDAYMIFGQTLGKISGALQSVRFSEIVVSIRNVMIAISSNIYDT
                     LNIIKNILNSEFFSNLVQGFTFCAVVITKSLGSIVNTALNIVNIFAQNWSIIKPIVFG
                     VASVFILFRGVLLATKIATIGNVIANVAHAASSSLSALMTNIQAAALMRSNGATLSAT
                     IATWGLNAALLACPITWVVLGILAFVVVVFVAVAAVNKFAGTSLTALGVIVGAVFAAV
                     AAIQNVMIWLLNGCIAVNEGITNGWNQCVYLMKQAIAKGVIFIIEKMASLNNSVNNAG
                     NALGKAFIDGANIAIRGVNKLIDLINKIPGINIGKVGEATFTPVKADNSYIKQQIDSL
                     NRWVGDAPEKVKLERMGYKDIGAAFQKGNALGTKWQNAITDKFKDTFDINKMLEDAKK
                     KLGLDDLWNKQNPLNNLGGFGGDLGKNVKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQ
                     ETINRFTGVNIKIDMNNTNNISKDTDVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            7183..7872
                     /locus_tag="KRQ43_002620"
     CDS             7183..7872
                     /locus_tag="KRQ43_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBH2742968.1"
                     /translation="MAYDFYLDGVQLPIAPPKLEVKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFCRGQFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDADNGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNATNTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKNLSKY
                     TIYKGQVLKLG"
     gene            7865..9757
                     /locus_tag="KRQ43_002621"
     CDS             7865..9757
                     /locus_tag="KRQ43_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH2742969.1"
                     /translation="MVDELVLANDRDVRLVIAHWEDFYEPAVIDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKILAKDFNLKYNVIEDTKYKISRVEENKTLFDMILTALDDTLRE
                     KKEMYTLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSAHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     ALGDIRVRAGCLVPVFLNLGDIELQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSIMKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLNKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDILLANASECKKFGRKNGYIIIGGDEEQTYQVEGNNQSNTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNNFDCSGFTQWCYKQIGIKIPRTASAQSKAGKAVD
                     LKDRSKWKAGDLLCRIGGGSSNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            9771..10031
                     /locus_tag="KRQ43_002622"
     CDS             9771..10031
                     /locus_tag="KRQ43_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBH2742970.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKMGDKLVLIRMQGGQQYLILDRM"
     gene            10036..10455
                     /locus_tag="KRQ43_002623"
     CDS             10036..10455
                     /locus_tag="KRQ43_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH2742971.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLHIEKSKIDGICDD
                     VEALKQTIFLILNTERYEHLIYSRNYGVELNDLIGEPISYVIPELERRITEALIQDDR
                     IENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV"
     gene            10456..11505
                     /locus_tag="KRQ43_002624"
     CDS             10456..11505
                     /locus_tag="KRQ43_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH2742972.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLEATHTIAKGVFNIDIPLDSRFNLGE
                     YNYVAIERISEKTYKMKCETTGPVFELGKLIPIEYIDGLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNIQNYRDEVNKIQDVGGVKVYPTWDGGGTVKLVIINSNFKV
                     PSEELVNLVQEEIDPIGHQGEGLGLAPIGHRVTVEGVTSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINDVKSNL
                     TIDSNSIVVRGEVVG"
     gene            11498..12115
                     /locus_tag="KRQ43_002625"
     CDS             11498..12115
                     /locus_tag="KRQ43_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBH2742973.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            12127..13152
                     /locus_tag="KRQ43_002626"
     CDS             12127..13152
                     /locus_tag="KRQ43_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH2742974.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTELKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNINNIELKIDPTIIFATLKDIQDLDAK
                     ISNVNTKIDTTKTELTSNIETAKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTIT
                     IDDWIDNQEGGFKATVTHGLLTQRITVSIIDATTKDNVVPDFTIIDDNSIEVRSGVKV
                     ELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIHEEIGKVAEQLTGINSNIISTV
                     NNDILPI"
     gene            13169..14695
                     /locus_tag="KRQ43_002627"
     CDS             13169..14695
                     /locus_tag="KRQ43_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742975.1"
                     /translation="MALSMSYFNLPDKRKYTKNLAFNPFAGGRQNFEWTGGDHGLNGE
                     FKETCLSCTYNGSTLNWGSGNVWVLGEYGQYTFTYNCESMHVDTQQKFPYTSNRIITI
                     KGRPVISGSDTSLGNKRKGFSVDFTVSDDTPNVNLIVRAYLDDKLIQNITPVVQNSTL
                     TATVTDSQLNSLSVDGNHKLKIQLNDGYDNFDRIFTFKKIEKGIDISTSLVTDSQAKF
                     TVTKIYSELTKIECYLDETLKETFTTDLYSEKTINYELIDNAIHTLKIVVTDAENVVE
                     EKVISISKNIMPLQPDATLQDISTKLTEIGQGVRNGKTSIINTLALKNIDASLNNTLV
                     ELSEKIKGGFDSGDASLQDLMNQLTQANNTISQLNTKYKVASGTVTSFADSTKIAYPY
                     LTDNVTKPGSWIKVSNLGFKPNIFFADFDYYDAEYKNNYKLFLFACNGVATQRGVDFS
                     SVTSFIRKSGDEYFHANGWLYSNSEGDVYFNNTGVQIPAYNFDSTQKHTYKWYAIKFI
                     "
     gene            14710..15003
                     /locus_tag="KRQ43_002628"
     CDS             14710..15003
                     /locus_tag="KRQ43_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742976.1"
                     /translation="MNVPNRIIYDQTGRTIFETGESCGDVLPHYTITELHYIDIEYGS
                     IDYTRNRVIGINIETKEPILEEIPVYITDEEKRIQELENQLLIAENEKVGGLL"
     gene            15003..15185
                     /locus_tag="KRQ43_002629"
     CDS             15003..15185
                     /locus_tag="KRQ43_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742977.1"
                     /translation="MNINNVVVRILAERILSKGLNPLKNREFQLDDVTNTEYRKAVED
                     YIIKNSGVVEGAEPTI"
     gene            15219..15785
                     /locus_tag="KRQ43_002630"
     CDS             15219..15785
                     /locus_tag="KRQ43_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742978.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTESKFTSENVEGALKECIDR
                     ADEAFQEADSGKTLLSTAIGSPTTSEQTFQDYANYITGFKSNISNLETQLKSKYSIRY
                     GPIDGYDGNPFSANFGKSASYLIVYVYFRRSVYYYNPSGSSLGSNTGGSERAWITINS
                     NKTGFSVHSYDTSYESYPFTGYYIACFA"
     gene            15816..16106
                     /locus_tag="KRQ43_002631"
     CDS             15816..16106
                     /locus_tag="KRQ43_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2742979.1"
                     /translation="MEEISINLLCAVAGVVISYLAFRNNSNRKIQDETETTTKLEQQI
                     TFLCENVRDIKHDVAKFNTSFLDISERVAKIEASTKQAHLRIDEIVNRIGGK"
     gene            16110..16367
                     /locus_tag="KRQ43_002632"
     CDS             16110..16367
                     /locus_tag="KRQ43_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBH2742980.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLNPVAVLQGVICWGVAIGINQTYKQLKDGEK"
     gene            16628..17491
                     /locus_tag="KRQ43_002633"
     CDS             16628..17491
                     /locus_tag="KRQ43_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HBH2742981.1"
                     /translation="MVEVKEEKTFDEQIDILKSRGLIINDKEDAKFVLSNVNYYRFTA
                     YLLSFKNDDGSYKEGTTFEEVYDIYRFNKEFRILLTDLLGSIEIAFRTYIAYTLAIKH
                     GACGYLERESFKDEKFYINFLTALEREKSNNSDKLFIIHHKEKYEGKLPIWVATEIMT
                     FGMLSKLYSNMLPEDTRYIKNNLCRVNTLLVKSWLQSLTQVRNQCAHYGRIYNNNFRI
                     ITIKNEYKKYNLDNKKIFSYILAMKHLTMDKLIWNSFFIKLQKLINDYNNSIDLKLIG
                     FPNNWIEILAK"
     gene            17570..18382
                     /locus_tag="KRQ43_002634"
     CDS             17570..18382
                     /locus_tag="KRQ43_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH2742982.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKTYKIPRVNSGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFRNRRAKLDKGLYILNSSNPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKISATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVIGGAACEKIGSMTKEKFTMIKGNDRFDTLYKALDFINR"
     gene            18476..20875
                     /locus_tag="KRQ43_002635"
     CDS             18476..20875
                     /locus_tag="KRQ43_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH2742983.1"
                     /translation="MIFKKYIKSLLIVVSVTLIMNKSILFVNALDLESNNNIKSYKRK
                     NVKEIDISNKFVDESFRRDIVEKVLDNRDDPLTNEVASKDNYKIYESDLNKIESCLEL
                     DLHKNPDVSNPNKIDNLDGIENFRNLEKLDCSSNNLESVDLSKNIKLKYLDISGNKIL
                     NIDLKNNNLINELHCDANKLSNLDLKNNKNLVSLFFTSNELTEIDLSNNVNLENLQFL
                     NNNLKSIDLSHNKKLKSLNCTNNKLKSLDLSNNVFLKNLSCSGNNLSKLNIKGLTSLE
                     YLGCAKNKLQDLDVSTNIKLDSLLCGKNSLTKIDISKNKELNSLECSGQYIEKSIIKN
                     GENIVVDIGIENSKLKELYPQNYNISTGFLTWENLSDFPNSISYSLEYEYGPVNDTET
                     MDVNISIDKLVKCRIRYIDYDGSIINEKEISDNSSINEIQINPQRENYEFSGWRNNKD
                     EKIYTSEQVSKLVFDDSTDFIATYKRKSTGSSGSSGGTSSKEDFNIAPSKEKITGADR
                     NETSVKISQKGWNKADNIVLINDSSISDALSATPFAKSKDAPILLTKNNNLNKLTEKE
                     INRLEAKNVYIVGGLKSVDEKVVSDLKKKGLNVIRISGNDRYETSIKLAKELDKNSNL
                     SKVVVVNGEKGLADAVSMGAISAKEEMPILLTNQNDDMKDIKDLIANKNISKSYVIGG
                     ESLFNNKEVNNTLPSVTKIAGSDRTETNSKVISHFYSKDTLNDLYVAKNGMNKQDDLV
                     DALSVGVLAGKTESPVVLVGNGLDDSQKELIKNKKFKNITQIGGNGNEKAFNEVENLV
                     K"
     gene            complement(20916..21101)
                     /locus_tag="KRQ43_002636"
     CDS             complement(20916..21101)
                     /locus_tag="KRQ43_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBH2742984.1"
                     /translation="MILLEQRKLRIGFNKSGKGSFTPRLILPMSWIKEMNISPDERDV
                     LVTFEDGKIIIEKTENE"
     gene            21796..22473
                     /locus_tag="KRQ43_002637"
     CDS             21796..22473
                     /locus_tag="KRQ43_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH2742985.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSRLYFDLSTPGPNHNTKIDINPPS
                     FEKPLKK"
     gene            22647..24683
                     /locus_tag="KRQ43_002638"
     CDS             22647..24683
                     /locus_tag="KRQ43_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HBH2742986.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLKNVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(24874..25440)
                     /locus_tag="KRQ43_002639"
     CDS             complement(24874..25440)
                     /locus_tag="KRQ43_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2742987.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKND"
     gene            25724..26251
                     /locus_tag="KRQ43_002640"
                     /pseudo
     CDS             25724..26251
                     /locus_tag="KRQ43_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
BASE COUNT        10615 a         2853 c         4609 g         8186 t
ORIGIN      
        1 tagaaaaaat attgtttata taaaataaaa aataaaaatt tttattaaaa aaatgaaaac
       61 ttgattataa agcaattaat ttataaaata tatataaata agtaggtatt tatttacttg
      121 aatttcattg tttatataaa aaaaatggaa aaatatgtaa taattatagg ttataataat
      181 tgtagcaagg ataataatcg aaagtgcgaa gggtgattat tttcatatta aacgccaaat
      241 tccaaataag gaaggaggtg aaattatatg ataggttttt tattaagcat actagctggt
      301 gttatatcag cttatattta tgacaaaata aaaaatcacc cagacgccaa taagggtgat
      361 ttaaaaaaat aatattttca cttaacaact gaaaataatc actctttgta ggaataaatt
      421 atttccttgc ttttattata ccacaaattg gtacagatat tcaaaaataa tatttttatg
      481 atataataaa aatgtagaga ttttgcagtg agcgatattt gtgataaatt gaagtttaac
      541 agttgcaata taaggcgttg agggtgtgtg ataaatgtta tcaattgcac tactcatggt
      601 tcactgcaaa tttaagagag ttgtatatgt gtaggtattg aaaatactca acttattttg
      661 gggttttaga ttaactatat ggaatgtaaa tgttgtaaga agtatcattc tattttttaa
      721 tctttctgtt ttagattaac tatatggaat gtaaatttca gtgagaataa gctttattgt
      781 cgatgtaaca ctcgttttag attaactata tggaatgtaa atagtacata taatgagtct
      841 ttaacatcag ttatgaaagg ttttagatta actatatgga atgtaaatga ttgtacttta
      901 gcgtctgcac tagctttgtc tatcgtttta gattaactat atggaatgta aattatttta
      961 cagatgaaca attacagtta cttcttgaat gttttatatt aactatgtgg attcaaaatt
     1021 aaatagaaaa aagaaagcac ttacttaaat agtaggtgct tttgttttgc tcaaattact
     1081 taattataaa gttgctaagt acaacttttt agaattatac aatataaaaa tgcactaaag
     1141 tgattgattt tgctcaagtt ggtcggttga gtaaaataat tagaaaaaaa tgttaaaaaa
     1201 ctcttgaaaa gtgtcgcgat acaatgtata attatattat cgcgatacag aaaagaggtg
     1261 aaaattatta ctgatagcag tagagcagat tacttcaagc agagacgaca gaataaaaaa
     1321 acttttagtg ttctactaga tagagagaaa gtagagaaaa ttgaagaaca tttaaaaaag
     1381 cagaacaaga ctaaaactat ttggcttgaa gaaaagatta atgaagagct agaaaaagag
     1441 gaataaaaaa taagagacgt tctccccgac caaagattga acatccctta ttgacgtata
     1501 ttatatacac taactatagt atacgtcatt ccttgaaaaa attcaattaa ggagtgtaat
     1561 agttatgaaa aatttaatag taaaagagtt caatggaagt caaatttata cttttatgtg
     1621 gaaagaaaaa tcttgttgga tagctaatca aatagttgga ttattcgatt atgctgatgt
     1681 atctaaaaca atacaggatt gcataaaagc agaagacttt gagattgaac aagagtatga
     1741 tgtattgaaa ggaaatgaat ttaatgattt tgtaactact ttaaatgtag tcgcaaataa
     1801 tataattagt aataaagcta gaagtataac tattttttat gaagatggtt tatatggatt
     1861 tttacaatac acagacaaac ctattggtgt acagtttagg aaatggctta gacgagaagt
     1921 tttaccaagc ataagacaaa ctggtgcata cataactaac aatgctaatc ccgaaaaact
     1981 aagagaaaaa gcaagtgaga ttgagaaatt acagttagct tacaatagta catctatgtt
     2041 aaaagaacta ttagatggtg caggctttga caataaatcc aaactattaa cagctaaaac
     2101 attatataag aaagcaggaa ttgatttacc aatagagata aacgaagaag aacattattt
     2161 tgatacaaag caaatagcat ctaaactgaa aatatattct aagagtaata aaccagcaca
     2221 gttggctgtt tgtgaaatta ttaaaaagat tgatttagaa gaaaacgaag tcaaaggcgt
     2281 ttgggaaact aatggttctt ggactggtac tgtaaataaa tatacaaaga gtgtaataga
     2341 taaggttaga aattggatag aggaaaataa tagacctact aagattgcag gtgaaaagaa
     2401 gaattatcat gtggtttata agattgagta aatttataag attgtattaa ataatttagt
     2461 ttagttttgg ggggattaat acaatgcatg agaatttact tgatagtata gatattgaaa
     2521 agagaaaaga agaatttaga attaaacttt tgaaaataag agaaacagat atagatatat
     2581 ataataagat agaaagtata gtatataaac tttcttagaa aaaattagag aaaaataatt
     2641 aaataaatag ataaagcact tggatatttc actgtttcaa gtgctttata tggtaaaaaa
     2701 tggtataata aaatatagga attttgcagt gttcgatttt tctactcaag tatagtttaa
     2761 caattggaat acaaggcatt gagaaggttt gataagtgtt atcaattgca ctattacccg
     2821 ctcactgcaa atttgagaaa gttatatgtg tgtaagtctt ggaaatacac aatttatttt
     2881 ggggttttat attaactata tggaatgtaa atctttgtaa tggtagtgta tttaagattg
     2941 aaacatcaag ttttatatta actatatgga atgtaaatca acattagtag ttgtctttat
     3001 acacatagca tcacgtttta tattaactat atggaatgta aatacagctc ccaagacata
     3061 caacgaatct gtaacatcag tgttttatat taactatgtg gtatgtaaaa gacttattta
     3121 cagctttatt tgctaaatca gaaggtttta tattaactat gtggacttaa aattaaaaat
     3181 aattaaaaaa cacttactaa tgtaggtgtt tttttattga aaggaagtga ttataatgta
     3241 aaaattttga agatatagta taatattctt ataaaatata atttaggggg atattatgag
     3301 agaaggaaag agaagaagag gatgtctatt ttggtttatt cttattattt tattttctgg
     3361 agttgttgga gcaatagcag ggaacagtac taataatgaa agcactgaaa aacagaaaga
     3421 ggatttaact aaatatattg gtgaagaagg tagtatagga gatttaaaat taactgttaa
     3481 tagcatttca aaagctagtg aaatatcagt agcatctggt tatttagcat acactccaga
     3541 tagtggcaaa tatggtatta taaatttaac aataaaaaat caaactaagg aaagccaatc
     3601 ttttatgcta aattcattca cattaatagg accagatgat tcaaaatatg ttccatcttt
     3661 attgattgat gtaggaaata aatatataac tatggatact gtaaatccta atttagatgt
     3721 aacaggtaat attgcatttg aaattcctaa ggatttacta gtttctgatt gtaaactaaa
     3781 atatagtggt tcagagcaag aatttatatt aaaagaaaaa taatatatag atttaaaaat
     3841 atgaagcatt tactttaaat aagtaagtgc ttttttaatt aaaaggaggt gataataatg
     3901 taaaaatttt acttatatag tataattaca ttataaaatt attgtactgg ggggaatctt
     3961 atggggttat ttggaaagaa aaaagcagat atatgttgta tttgtaatac tgagatagga
     4021 gtactgaata ttgaagatgg ttggatatgc aattcttgtt ttaaagaata ttgtgatgca
     4081 ctttctatga ctaaagcacc taaaatttta agaaaattag atattgaaaa gactatatca
     4141 tcaactaaaa aaaataatga acttcaaaaa atatttaata caactaataa tatagaaaac
     4201 tatatagaat ttgatgaaga taataaaaaa tggcttgtgt ctaaaaaaag tataaacgat
     4261 aaaaaaactc ctatcattca ttcttatgaa gatatcgtga aatttgaact tcttgaaaat
     4321 ggtgaaactg taactaaagg aggaatagga agagctttag cgggaggaat tttatttgga
     4381 gaagcaggag ctatagttgg agggataaca ggtaaaaaaa caacaagaaa agttgttgat
     4441 acatttaaaa ttaaaataac aattaataat attgataatc ctattgagta tatcgaatta
     4501 attaataaaa aaacaaaaac taattctagt gcttatgaga aagcttacaa agatgcccat
     4561 aaaattttat caacattatc tgctattaca caaagcatta aagagacaga caatataaat
     4621 actaaatctg tagcagatga gatattaaaa tataagaatc ttttggatat ggaagctatt
     4681 acacaagatg aatttaatac taagaaaaaa gaattattga atttgtaata taataaacac
     4741 ttactaatgt aggtgttttt ttatatggaa atttatgaaa ggagagtgag aaagtggcaa
     4801 cgatacaaac ttcaataaag attttcgacg gaatgacacc tgcttttagg aatatgacta
     4861 catctattaa tacgacaatt aatagccttg aaaggttaca acaaagattg cataatccgc
     4921 ttaacacagg tgggatacaa gcatctcaac aaagtttaaa caatattgaa aacatattaa
     4981 ccaggataga acagaaaatt ggaagaaata caaatgaaca agaaaacttt aataataaga
     5041 taaagcaagg aagtgaagca ggttctctat tagtatctaa actcaaaagt ttggctggca
     5101 tatatattgg aataagaggt atagaaagta ttacaaaagc agcagataca attgcaagta
     5161 caaaagcacg tttaaattta atgaatgatg gattacagac aacagaacaa cttaataaga
     5221 tgatttattt atctgctcaa agtgcaagag ctagttatgc agatacggca gcacaagtcg
     5281 ctaaacttgg aatattagca ggagatgctt ttggaagttc ggcagaggtg ataaagttta
     5341 cagaacttat gaataaagct tttgtaattg gaggaacatc agcaaatgaa gctagtgcgg
     5401 ctatgtatca gcttactcaa gctatgggtg cagggaaact tcaaggtgat gaatttcgct
     5461 ctataatgga aaatgcacct ttattagcca ctaaaatagc tgatgcaatg ggaaaaacta
     5521 aagaccaatt aaaggaattg tcaagtagtg gagcaataac agcagatgtt ataagaaatg
     5581 cactatttaa agcttctgat gagatagaaa agaaattcgc aagtatgcca gtcactttta
     5641 gtcaagcact tactatgatg aaaaatgacg cctacatgat ttttgggcaa accctcggaa
     5701 agataagtgg agcattgcaa agcgttagat ttagtgaaat tgttgtatct ataagaaatg
     5761 ttatgattgc aatatcttca aacatttacg atacattaaa tattataaaa aatattttaa
     5821 atagtgaatt cttttcaaac ttagtgcaag gatttacatt ttgtgcggta gtaataacta
     5881 aaagcttagg ttctattgta aatactgcat taaatatagt taatatattt gcacaaaatt
     5941 ggagtataat aaaacctatt gtatttggtg tagcttctgt ttttatattg tttagagggg
     6001 ttttgctagc gactaaaata gctacaatag gtaacgtaat tgcgaatgtt gctcacgctg
     6061 cttcctcttc actatcagca cttatgacta atatacaagc agcagcactg atgcgttcga
     6121 atggagctac tttatcagca acaatagcca cttggggttt aaatgcagct ttattagctt
     6181 gtccaatcac atgggtagta ttaggtattc tagcatttgt agtagtagtt tttgttgcag
     6241 tagcagcagt aaacaaattc gcaggtacaa gtttaactgc cttaggagta attgtgggtg
     6301 ctgtatttgc agcagtggca gcaatacaaa atgttatgat ttggttatta aatggctgta
     6361 tagctgtaaa tgaaggcatt acaaatggtt ggaatcaatg tgtatatcta atgaaacaag
     6421 ctattgcaaa aggtgtaatc tttataatcg agaaaatggc atctctaaat aattctgtaa
     6481 ataatgctgg aaatgcactt gggaaagctt tcatagatgg ggcaaatatc gcaatacgag
     6541 gtgtaaacaa attaattgac ctaataaata aaataccagg gataaatatt ggtaaagtag
     6601 gagaggcaac gtttacgcca gttaaggcag ataatagtta catcaaacaa cagattgata
     6661 gcttaaacag atgggtagga gacgcaccag agaaagtaaa attggagcga atgggataca
     6721 aagatattgg agcagcattt caaaaaggaa atgcacttgg aactaaatgg caaaatgcta
     6781 taactgataa atttaaagat acttttgaca ttaataagat gctagaagat gcaaagaaaa
     6841 aattaggatt agacgatttg tggaataaac aaaatccttt aaacaacctt ggtggatttg
     6901 gtggagattt aggaaaaaat gtaaaggaca cggcaggcaa tactgcaaag atggcaaaga
     6961 ctatggataa aagtcaagag gacttaaaat acttaagaga tatagcagag caagaaacaa
     7021 tcaatcgatt cacaggagta aacattaaaa tagatatgaa caatacaaac aacataagta
     7081 aagatacaga tgttgatgga atagttaatg tcttaactga aaaactgaac gatgctatgg
     7141 ttgtatcagc ggaaggaata gtttaggaag gagagtgaga aaatggctta tgatttttac
     7201 ctagatggag tacaactacc aatcgcacca cccaagcttg aagtcaaagt gacaaacaag
     7261 aacaagacag ttgatttgat aaatactgga gaagtaaaca tattaaaaaa agaaggatta
     7321 tctgaaataa gttttgaagc agaatttaca cataataaac tacctttttg tagaggtcaa
     7381 tttagagatg ttcaattctt tttaagtaag ctagaattac taaaaactga ttgtaagcca
     7441 tttcaattta ttgtatctcg tgagttaggt aacaaggtct tatttaacac taatataaaa
     7501 gtatctcttg aagagtatgc tatttcagaa gatgcagata atggctcaga tacaaaagtt
     7561 gcaataaaat taaagcaata tagagattac tcaactaaaa agttagttct tgcccctcct
     7621 aaaaatgaga ctggtagacc taatgtaaag atagagccaa aacgagttga ttcagtcaat
     7681 gccacaaaca ctaaaacata tacagtaaaa gcaggggata gcctttggtc aatttgtcag
     7741 aaacaacttg gtaatggttc attatataag aaagtatacg aactaaataa atctatgatg
     7801 gataaggcaa ataagggcaa aaacttaagt aaatacacta tttataaagg gcaggtgtta
     7861 aaacttggtt gatgaattag tgttagcaaa tgatagagat gtaagattag taatagctca
     7921 ttgggaagat ttctacgaac ctgctgtcat tgatggtatc acatgggaga tagaaagacg
     7981 aggtacacct tctaagttag agtttacaat agtcatggat gatatactag agttttgcga
     8041 aggaaattct gtaaggctgt attataaagg aataggcata ttttatggat atatatttca
     8101 aaagaaaaga gataaagaaa atcacattaa aattgttgct tacgaccagt tgagatattt
     8161 taagaataaa gatacttatg tatatagtaa taaaactgca agtgaacttg taaaaatctt
     8221 ggctaaagat tttaatttaa aatacaatgt catagaagat actaagtata aaatatctag
     8281 agtcgaagaa aataaaacac tctttgacat gatactaaca gcactagatg atactttaag
     8341 agagaaaaaa gaaatgtata ccttgtatga tgattttgga agaataacat taaagaatgt
     8401 tgcatcaatg aaactagata ctgtcatgaa caatgatgta attgaggatt ttgactataa
     8461 ttcatcaata gatagtgata cttacacaaa gattaaactt gtaagagaca acgaggagtc
     8521 aggaaaaagg gatgtatata ttgctcaaga ctcagctcac atgagaagtt ggggaatact
     8581 tcaaatgttt gatacagtag acaaaaacat gagtgaagca gagataaaac aaaagtgtga
     8641 tatacttcta aaactatata ataagaaaac taagtcatta agtttaaaaa atgcacttgg
     8701 agatattaga gtgagagcag gttgtttagt acctgttttt ttaaatctag gagatattga
     8761 attgcaaaat tatatgttag ttgagaaagt aaaacataca tttgaaaata attcacattt
     8821 catggatttg accttggttg atggagacga atttgcttca tattcttcaa gctcatatag
     8881 tagtggaaat actaataata aagatgaaaa gaaaaatggt cctgcacaaa gtattatgaa
     8941 aaaaaataca ggtaaaaaag ttcctgctat atttactgca tattatccag gaaacaatgc
     9001 aatggaaggt ggaaaaacag attgcaatgg aaagccactt gatgtaaaat caagaactgt
     9061 tgctggtcca atgaatcgag aaggagttaa gaaaacttgg tatactgatg attttctaaa
     9121 taaacatcca gtttttgaat atggagataa agtaaaaatt atacttcctg gtactgccta
     9181 tgacaacaaa gtatatacag ttaaagataa tggaggaaga atatatgttg aaacaaacgg
     9241 aacatatcat atagatatac tattagctaa tgctagtgaa tgtaaaaaat ttggtagaaa
     9301 gaatggctat ataattatag gtggagatga agaacaaaca tatcaagttg aaggtaataa
     9361 ccaaagtaat acaaataaca attctaaaga agataaatta attagtatag caaaaagtaa
     9421 actgggttgt aattatgtgt atggagcaga aggtcctaat aattttgatt gcagtgggtt
     9481 tactcaatgg tgttataaac aaataggtat aaaaattcct cgtactgctt ctgcacaaag
     9541 taaagcagga aaagcagtag atttaaaaga tagaagcaag tggaaagcag gagacttatt
     9601 atgtagaatt ggtggaggaa gtagtaatca tgttgtaatg tacattggaa acaatcaaat
     9661 aattcattca ccacaaacag gagatgtggt aaaaatagag tctgttaatt cttatagaaa
     9721 aggaaaagca tacacacatg tgagaagatt tatataagtg aggtggcaat atgagccaag
     9781 atttattaca gataataaaa aaagctgcaa tggatgcagt agaaacaagc aacccaatga
     9841 gggttgtatt tggaacaata gaaagtatta gtcctctaag agttaagata gaacaaaaac
     9901 tatctattgg tgaaattttt ctaatacaaa cagatacatt taaaagatat acagataaaa
     9961 aaatgggaga taaattagtc ttaattcgta tgcaaggagg gcaacaatac ttgattttag
    10021 ataggatgtg ataaagtgtt accaagtgat aatttagatt atgatattga agatgtatca
    10081 ataattaatt ttgatgtaag acaagagcca agtaagacat ttaaacttca tatagaaaag
    10141 tctaagattg atggtatttg tgatgatgta gaagcattaa aacaaaccat ttttttaatt
    10201 ttaaatactg aaaggtatga gcatcttatt tattctagaa attatggtgt tgaattaaat
    10261 gatttaattg gagaacctat ttcatatgta atacccgaac ttgaaagaag gataacagaa
    10321 gcactaattc aagatgatag gattgaaaat atagataatt ttgagtttca aaatataaag
    10381 ggtaaagtac aatgtagatt ttcagttcat acaaaatatg gaaatataaa agcagagaag
    10441 gtggtgagtg tataattgtt tgagttaatg acatttgaaa atataattaa aagaatgtta
    10501 gatagtgtac cagatacttt tgataaaagg gaaggttcta taatatataa tgctcttgct
    10561 cctgttgcta tagaacttac agaaacatac attgctatgg atgaattact agaccaaaca
    10621 ttcgtagata ctgctagtta ttattattta gagaagagat gtaaagaaag gggaataaca
    10681 ccacttgaag ccactcatac gattgctaaa ggagttttta acatagatat tccacttgat
    10741 tctaggttta atctaggaga atataactat gtagcaattg agagaatatc tgaaaaaaca
    10801 tataaaatga aatgtgaaac tactggacct gtatttgagt taggaaaact aatacctatt
    10861 gaatatatag atggtcttga aactgctgaa ctaactgaaa tcttgataaa tggagaggat
    10921 gaagagtcag aagatagttt aagacaaaga tattatgata gcctaaattc acagagtttt
    10981 ggcgggaata tacaaaacta tagggatgaa gttaacaaaa tacaagatgt tggaggagtt
    11041 aaagtttatc caacttggga tggaggtggg actgttaagt tagtaataat taactctaat
    11101 tttaaagtgc caagtgaaga attagtaaac ttagttcaag aagaaattga cccaattgga
    11161 caccaaggag aaggcttagg attagcaccg attggacacc gagtcacagt tgaaggagtt
    11221 acaagtacaa ctataaacat atcagcagaa ataacataca aaaatggcta cacttgggag
    11281 aatataaaat caattgcaga agaagcaata gacgactatt taaatgaact taacatgagt
    11341 tgggaagatg aagaaaactt aatagtccgt atatctcaaa ttgaaactag attacttagt
    11401 attgatggag tattagacat tgcaaataca atgataaatg atgttaaatc taatctaaca
    11461 atagatagta acagcatagt agtgagaggt gaggtagttg gataaagaga ttaatctaat
    11521 aaattacttg ccacaaattc tacaagataa agaagaatat ataaaagtat ttaatgtaga
    11581 aaataaagaa ataaaaacac tacatgataa attaaaggac ctatcaaatg accagttttt
    11641 agaggaccta actataagtg gtataaaaag atgggaaaag ataatgtcta taactcctaa
    11701 aagtaatgag agtttagaag atagaaggtt taggattttt agtaaatata taagtaaatt
    11761 accttactca gagagatttt taaggaactg gctagataat gtagttggag aaggcaatta
    11821 tgaattaact attaataatg ctacttataa catacacctt gagagtgatg ctagaaatca
    11881 agattggttt gaggaagttc attcttttgt aagtaatatt aagccatgta atatgacttt
    11941 agattacact agagtgctta taagcaaaga caattatatg aattttggta taacaaccct
    12001 aatgggtcaa gaaataacta tatacccttg gagtccacca gatatagaaa cttatggaga
    12061 aattgatgta ttaactggca atggagttgg ataccaagag ataacaatat tttaggaggt
    12121 gatatattgg ctatagataa aagttattac actataatta cagatgtagg aaaagcaaag
    12181 atagcaaatg caagtgtcac aggtaataaa gtagggtttg taaaaattca acttggtgat
    12241 ggtggaggaa gtgagtatac tcctactgaa agtcagacag aacttaaaaa tgtggtatgg
    12301 gaaggcaaca tcggaaatac aaccacagat gaaactgcgc caaactgcat aatattagag
    12361 agtttaatac catcaagtgt aggtggattt atgataagag aaataggata tttagatgat
    12421 gaaaataatc taattgcaat ctctaaatat aaagaatgtt ataaaccttc tatagaacaa
    12481 ggagcagttg ttgatatgaa ggttaaaact gtgcttattg tatctaatat aaataatata
    12541 gaacttaaaa ttgaccctac aataattttt gctacgctca aagatataca ggatttagat
    12601 gctaaaataa gcaatgtaaa cactaaaatt gatacaacta aaacagagtt aacaagcaac
    12661 atagaaactg ctaagacaga gttaaacact agaattgaca cagaaaatga gaaacaaaat
    12721 attaaaattg accagctaat agcaggtggt tcaaatgttg catctactca aacaataaca
    12781 attgatgatt ggatagataa tcaagaaggt ggattcaaag caactgtaac acatggttta
    12841 ttaacacaga gaataactgt aagtattata gatgctacta caaaagataa tgtagtaccc
    12901 gatttcacaa ttatagacga taattctatt gaggttagaa gtggagtaaa agttgagtta
    12961 aatgtttatg tgattaatgg gaatgcagag actcatttta ttaatgcgac tgtagatgat
    13021 aatagagtgt ctgaaatgac tacttattca tcaaaaaaga tacatgaaga aattggtaag
    13081 gtagcagagc aactgacagg aattaatagt aatattatat cgactgtaaa taacgacata
    13141 ctacctatat agaaaggagc gtgaaaaaat ggcgttatca atgagttatt ttaatttacc
    13201 tgacaaaaga aaatatacta aaaatcttgc atttaatcca tttgcaggtg gaaggcaaaa
    13261 ttttgagtgg actggtggtg accatggact aaatggtgag tttaaagaaa cttgcttaag
    13321 ttgcacttac aatggttcaa cattaaattg gggttcagga aatgtttggg tcttggggga
    13381 atatggtcaa tatacattta cttataattg tgaatcaatg catgtggata cacaacaaaa
    13441 atttccgtat acttctaata gaataataac tataaaaggt agacctgtaa tatctggttc
    13501 agatacttca cttgggaata aaagaaaagg atttagtgta gattttactg taagtgatga
    13561 tactccaaat gttaatttaa tagtacgtgc ttatcttgat gataaattaa tacaaaacat
    13621 tactcctgtt gtacaaaatt caactttaac agcaacagta acagatagtc aactaaactc
    13681 tttatccgta gatggaaatc acaaactaaa aatacaatta aatgatggat atgataattt
    13741 tgatagaatt tttactttta aaaaaataga aaagggaatt gatatatcaa catcattagt
    13801 aactgatagc caagctaagt ttactgtaac aaaaatatac agtgaattga caaaaataga
    13861 gtgttattta gatgaaacat taaaagagac ttttactaca gacttgtatt cagaaaagac
    13921 tataaactat gaacttatag acaatgcaat acacacatta aaaatagttg taactgatgc
    13981 agaaaatgtt gtagaagaaa aagttataag tataagtaag aatataatgc cattgcaacc
    14041 tgatgcaaca ttacaagata tatcaactaa gttaacagag attgggcaag gcgttagaaa
    14101 tggtaaaaca agcattataa atactttagc attaaagaat atagatgcaa gtttaaataa
    14161 tacactcgtt gagttatcag agaaaattaa gggaggtttt gatagtggag acgctagttt
    14221 acaagatttg atgaatcaat taacacaagc taataatact atatcgcagt taaatactaa
    14281 gtataaagtt gctagtggta cagttacttc ttttgcggat agtactaaaa ttgcttatcc
    14341 atatctaacc gacaatgtta ctaaacctgg ttcttggatt aaagttagta atttaggctt
    14401 taaacctaat attttctttg ctgattttga ttactatgat gctgaatata aaaataatta
    14461 taaacttttc cttttcgctt gtaatggtgt tgccacacaa agaggtgttg atttttcaag
    14521 tgttacatct tttatcagaa aaagtggtga tgagtatttt catgctaatg gatggctata
    14581 tagtaactca gagggggatg tctattttaa taatactggc gttcagattc cagcttataa
    14641 ctttgattca actcaaaaac atacttataa atggtatgct attaaattta tttaaaagga
    14701 ggaaaaaaca tgaatgttcc aaaccgaata atatatgacc aaacaggtag aacaatcttt
    14761 gaaacaggcg aatcctgtgg agatgtattg ccacattata caataacgga attgcattat
    14821 atagatattg aatatggaag tatagattat acaaggaata gagttatagg tataaatata
    14881 gaaacaaaag aaccgatttt agaagaaata ccagtatata taacagatga ggaaaagaga
    14941 atacaagagt tagaaaatca attattaatt gcagaaaatg agaaagtagg aggattatta
    15001 taatgaatat aaataatgtt gtagtaagaa tattagcaga aagaatatta agtaagggat
    15061 taaatcctct aaaaaataga gaatttcagt tagatgacgt gactaacaca gagtacagaa
    15121 aagctgtaga ggattatatt ataaaaaata gtggagtagt agaaggagca gaaccaacta
    15181 tatagagggt tcttttttta ttgaaagaag gtgactaaat gacttttaaa gagttggtta
    15241 ataaagttag aaatcttgta ttagaagcaa agaatgtaac tatagaagat acagaaagta
    15301 aatttacaag tgaaaatgta gaaggagcat tgaaagaatg tatagataga gcagatgagg
    15361 cttttcaaga agccgatagt ggaaaaacac ttttatcaac tgctatcggc tctcctacta
    15421 catcagaaca aacatttcaa gattatgcga actatattac aggatttaag agcaatataa
    15481 gcaatttaga aactcaattg aaaagcaaat attctattag atatggtcct attgatggat
    15541 atgatggtaa tcctttttct gctaattttg gcaagagtgc aagttacctt attgtctatg
    15601 tttactttag aagaagtgta tattattata atcccagtgg tagttcttta ggaagtaata
    15661 caggaggttc tgaacgtgca tggattacta taaacagcaa taaaactggt ttttcagttc
    15721 attcatatga tactagttat gagtcatatc cttttacagg ttattatatt gcttgtttcg
    15781 cataataaat tatattatta aaactaggag gatgtatgga agaaattagc ataaatctac
    15841 tatgtgcagt agcaggagtt gtaatatcct acttagcatt tagaaataac tcaaacagaa
    15901 agatacaaga tgaaacagaa acaactacaa aattagaaca acaaataact tttttatgtg
    15961 agaatgtaag agatataaag catgatgtag caaagtttaa tactagtttc ttagatatta
    16021 gtgaacgagt tgcaaaaata gaagcaagta caaaacaagc acatcttaga attgatgaaa
    16081 ttgtaaatag aattggagga aaataagaga tggataattt aataagtttt ataccagagc
    16141 agttgctaat tttagtagct gctctctcta ttataggtaa aggttgtaaa aaatataaac
    16201 aattagataa taaatacatt ccagtagtgt tactgatact tggaataggt ttctcaatat
    16261 ggatgctagg attaaatcct gttgcagtct tacaaggtgt aatttgttgg ggagttgcaa
    16321 taggtataaa tcaaacttac aaacagttga aggatggtga aaagtaatga aattaacaaa
    16381 aatattatta ctcacaaaaa tttaaaaaat ttcattaaat agagtatact tttatagcta
    16441 ataagtatat aataatagta cagaactcgt aaagcattta tatgctcaaa tatacgggac
    16501 attgattttt gaaggaaccc gccaagcttc ttttatagct caaataggcg ggacagataa
    16561 atttacccac taatattaat tggtgggttt tattatataa aagtatatct atgaaaaggt
    16621 gaaaacaatg gttgaagtaa aagaagaaaa aacatttgat gaacaaatag atattttaaa
    16681 aagtagagga ttaataataa atgataaaga agatgctaaa tttgtattaa gtaatgtcaa
    16741 ttattatagg tttacagcat atcttctaag ttttaagaat gatgatggct catataaaga
    16801 aggaactacg tttgaagaag tttatgatat atataggttt aataaggaat ttaggatatt
    16861 attaacagat ttgttaggga gcatagaaat agcatttagg acatacattg catatacatt
    16921 agcaattaaa catggtgctt gtggatatct agaaagggag agtttcaaag atgaaaaatt
    16981 ctatattaat tttttgacag cattagagag agaaaaaagt aataattcag ataagctttt
    17041 tattatacac cataaagaaa aatatgaagg aaaacttccc atttgggttg caacggaaat
    17101 aatgactttt ggtatgttgt caaaattata ttcaaacatg ttgccagaag atactagata
    17161 cataaaaaat aatttgtgta gagtgaatac tttattagtt aaatcttggt tacaatcatt
    17221 aacacaggtc agaaatcaat gcgctcatta tggtagaata tataataata atttccgtat
    17281 tataacaata aaaaacgaat ataaaaagta taacttggat aataaaaaga tattttctta
    17341 tatacttgct atgaagcatt tgactatgga taaattaatt tggaatagtt tttttataaa
    17401 acttcaaaag ttaattaatg attataataa ttctatagac ttaaagctta ttggttttcc
    17461 taataattgg atagagatat tggctaaata aaatagttac tttaagaagt ttataaacac
    17521 ttactatatg taagtgtttt tttattgaaa agaaggagga aaataaataa tgaaaatatg
    17581 tattacagta ggacacagta ttttaaaaag tggtgcatgc acttctgctg atggagtagt
    17641 taacgaatac caatacaata aatctcttgc accagtatta gcagatacat ttagaaaaga
    17701 gggtcataag gcagatgtaa taatatgtcc tgaaaagcag tttaaaacta aagcagaaga
    17761 aaagacttat aaaataccta gagttaatag tggaggatat gatttactta tagaactaca
    17821 tctaaatgca agtgatggtc aaggaaaagg ttcagaagtt ctatattata gtaataaagg
    17881 tttagagtat gcaactagaa tatgtaataa gctaggtaca gtatttagaa atagaagagc
    17941 taaattagat aaaggattat atatcttaaa tagttcaaat cctacagcag tattaattga
    18001 aagtttcttc tgtgataata aagaagatta tgagaaagct aagaaactag gtcatgaagg
    18061 tattgctaag ttaattgtag aaggtgtatt aaataaaaat ataaataatg agggagttaa
    18121 acagatgtac aaacatacaa ttgtttatga tggagaagtt gacaaaatct ctgcaactgt
    18181 agttggttgg ggttataatg atgggaaaat actgatatgt gatataaaag attacgtgcc
    18241 aggtcagacg caaaatcttt atgtcattgg tggtgcagca tgtgagaaga ttggttctat
    18301 gactaaagaa aaatttacta tgataaaggg taatgataga tttgatacac tttataaggc
    18361 attagatttt attaatagat agattatata aaatatttta gtatttcttg aaaatcataa
    18421 gtatggtaat atttagataa atattattta ttattaatag gtatgggggg agattatgat
    18481 atttaagaag tatataaaat cattactgat agttgttagt gttacattga taatgaacaa
    18541 atcaatatta tttgtaaatg cattagattt agagagtaac aataacataa aatcttataa
    18601 aagaaagaat gtaaaggaaa ttgatataag caataaattt gttgatgaat cctttagaag
    18661 agatattgtt gaaaaggtat tagataatag ggatgatcca ttaacaaatg aagttgcatc
    18721 aaaagataac tataaaatat atgaaagtga tttaaataaa attgagagtt gcttagagtt
    18781 agatttacat aaaaatccag atgtttctaa tccaaacaaa atagataatt tagatgggat
    18841 agaaaatttt agaaatctag aaaagcttga ttgtagttca aataatctag aaagtgtaga
    18901 tttaagtaaa aatataaaat taaaatatct agatattagt ggaaataaaa tattaaacat
    18961 tgatttaaaa aacaataatc ttattaatga attacattgt gatgcaaata aattatcaaa
    19021 tttagacctt aaaaataata aaaatttggt aagtttattt tttactagta atgaattaac
    19081 agagatagat ttaagtaata atgtgaactt agaaaattta caatttctta ataataattt
    19141 aaaaagtata gatttaagtc ataataaaaa gttgaaatct ctaaattgta ctaacaataa
    19201 acttaaatcc cttgatttaa gtaataatgt ttttttgaaa aatttaagtt gttcaggtaa
    19261 taacctgagt aaattaaata taaaaggact tacaagtctt gagtatttgg gatgtgctaa
    19321 gaataaatta caagatttag atgtatctac aaatataaaa ttagattctt tactttgtgg
    19381 gaaaaatagt ttaacaaaaa tagatataag taaaaataaa gaattaaatt cactggaatg
    19441 tagtggtcaa tatatagaaa aaagcattat aaaaaatggt gaaaatatag ttgtagatat
    19501 aggaattgaa aattcgaaat taaaggaatt atatccacaa aattataata tttcaacagg
    19561 ttttctaaca tgggaaaatc tttctgactt tccaaatagc ataagttata gtttggaata
    19621 tgaatatggt ccagtaaatg atacagagac tatggatgta aatatatcaa tagataaatt
    19681 agtgaaatgt agaatcagat atatagatta tgatggaagt ataattaatg aaaaagaaat
    19741 atcagataat tctagtataa atgaaattca aattaatcct caaagagaaa actatgagtt
    19801 tagtggttgg aggaacaata aagatgaaaa aatatataca tcagagcagg taagtaaatt
    19861 agtttttgat gatagtactg attttatagc aacttataaa agaaaatcaa caggatcaag
    19921 tggttcttct ggtggaactt caagtaaaga agattttaat atagcaccat ctaaggaaaa
    19981 aataacaggt gcagacagaa atgaaacatc agtgaaaata agtcaaaaag gatggaataa
    20041 agctgataat atagtgttaa taaatgactc tagcatatcg gatgctttat cagcaacacc
    20101 atttgctaag tctaaagatg caccaatatt acttactaaa aataataatt taaataaatt
    20161 aacagaaaaa gaaataaata gattagaagc aaaaaatgtg tacatagtgg gtggattaaa
    20221 gtctgttgat gaaaaagtag tgtctgattt aaagaaaaaa ggattaaatg taattagaat
    20281 atctggaaat gatagatatg aaacatcaat aaaacttgca aaagaattag acaaaaattc
    20341 taacctgtca aaagtagtag tggtaaatgg agaaaaggga ctagctgatg cagtaagtat
    20401 gggagctata tcagcaaaag aggaaatgcc aattcttctt actaatcaaa atgatgatat
    20461 gaaagatata aaagacttaa tagctaataa aaacatatca aaatcatatg taataggtgg
    20521 agaatcttta tttaataata aagaagtgaa taatacatta ccatctgtaa ctaaaatagc
    20581 aggttctgat agaacagaaa ctaactcaaa agtaataagt catttctata gcaaagatac
    20641 acttaatgac ttatatgtag ctaagaatgg aatgaataaa caagacgatt tagtagatgc
    20701 cttatcagta ggagtgcttg caggtaaaac tgaatctcca gtagtattag ttggaaatgg
    20761 attagatgat agccaaaaag agttaatcaa gaataaaaag tttaaaaata taactcaaat
    20821 tggtggaaat ggaaatgaaa aagcatttaa tgaagtagaa aacttagtta aatagattga
    20881 aaggtagtaa ctggaaatag ttactacctc cttttttatt cattttcagt tttttcaata
    20941 attatttttc catcctcaaa agtaacaaga acatcccttt catcaggaga gatattcatc
    21001 tctttaatcc atgacattgg aagtatcaat ctgggtgtaa aagagccttt gccactttta
    21061 ttaaatccaa ttctaagttt tctttgctcc aataatatca ttcctttcta ctattaataa
    21121 atgccagcaa taataaagta aataccaaag caataagagc tttaaaagta aaacttatta
    21181 ttatattaat aatatttaaa actatagtga taccaagaat aatcatacaa attctataaa
    21241 atttattatt catattaaat tagaaaatgt gttataatat tagaaagaag ctacctagaa
    21301 ggaaggtatt ttcctcctag gattgaaact tataattctt taatcaatct tagtattgcg
    21361 agtactagat taattaaaac taatgtgaaa gagaaagcat ttttaatttt attaaatttg
    21421 ttttctcttt tattttttct tctttctaat ctccccactt tcttacctcc tttctatatt
    21481 tatattatat catcacgtga cgtgaaagtc aataaatatt acatattttt caataaagtt
    21541 atattgataa actatatttt ttacaaataa aaataaatgg tgacaaaacc aaacttgcca
    21601 ccattttgcc accgaaaata aataatagaa taaatttaaa ttaaacataa taaaacataa
    21661 acaacaaaac tgaccttaat aaaacattga aataccaaca cttgtaaaaa ataacaacaa
    21721 taaacaaata acctagaata atattacaac ttaagtaaat aataattttg aataataatt
    21781 tacggaggta ttcatatgtt taaacacgat aaagcattat taaaagaagt aaaagtagaa
    21841 agaccaaatc ctcaatatgc tgttttaatg caagaacagt tgggtggtgc aaatggagag
    21901 ttaaaagcag ctatgcaata cttgtcccaa agttttagaa taaaagaccc tcaaataaaa
    21961 gatttatttc ttgatatagc agcagaagag cttagccata tggaaatggt agcacaaact
    22021 ataaatttat taaatggaca tgatgttgat tataatgcag ttaatacagg cgaaatagaa
    22081 acacatgtat taactggtct atcaccagtc ttaataaact catcaggagc tccttggact
    22141 gctaattatg ttacagttac aggggattta gtagctgact tactttcaaa tatagcttct
    22201 gaacaaagag ctaaggtagt ttatgagtac ttgtatagac aaatagatga taaatatgta
    22261 aaagaaacaa tagatttctt acttaacaga gaagaagcac ataatgctct atttagagat
    22321 gctttaaata aagttaaaga tacaggttca aatagagatt ttggagttac agaagattct
    22381 agattatatt tcgatttgtc tactccaggg ccaaatcaca atactaagat agatattaat
    22441 cctccttctt ttgaaaaacc tttaaaaaaa taatttgata ttttttatgt tgttttgttt
    22501 tagtagttat aaaaattatt tactagaaga attaattata tgaaaaatta aatatgtata
    22561 gttaaaaatg ggtatacact tattataagt gtatatctat ttgtttattg caaaacatat
    22621 aataaaataa caaatgaggt ggtattttgg acagtaatag aaaacctaat aatctaataa
    22681 atgaaaaatc tccatatctt ttacagcatg cttataatcc tataaactgg tatagttgga
    22741 atgatgaggc ttttaaaaaa gcaaaagaag aggataaacc aatattttta agtgtaggat
    22801 attcaacatg tcattggtgt catgttatgg aaaaagaatc ttttgaagat gaagaagttg
    22861 ctgaaataat gaatagaaac tttgtggcaa taaaagtaga taaagaggaa agacctgatg
    22921 tagatagcgt gtatatgaca gtttgccaag ctatgacagg tagtggtgga tggccaatga
    22981 ccataataat gacaccagat aaaaaacctt tttttgcggg aacatatttc ccaaaatatt
    23041 caaggtataa tagacctgga gttatagatt tattaaagaa tgtatctgaa aaatggaata
    23101 caagtaggga tatattaata aaatctggag atgaaataat agaagctctt aaggatgatt
    23161 ttggtgtaaa aaatactgag ggtgatttat caaaagagat gttgagttca tcagttagag
    23221 tatttaaggc catttatgat gaaaagtatg gtggttttgg taatgctcct aaatttccaa
    23281 gtcctcagaa tcttatgttt ttaatgaaat attatagcat agaaaaagat aaagatgtgt
    23341 taaaaatggt ggaaaaaact ttagatggaa tgtatagagg aggcttgttt gatcatattg
    23401 gatttgggtt ttcaagatac tctactgata aaaagtggtt ggctcctcat tttgaaaaaa
    23461 tgctatatga taatgctatg cttactatag cttttttaga tgcatataaa ataacaaaga
    23521 aagagttata taaagaaatt gctataaaaa ctatagatta tgtagttaga gagatgaagg
    23581 ataaagaagg tgggttttat tcagcacagg atgctgatag tgaaggtgaa gaaggtaaat
    23641 tttatacatt taatcctctt gagataattg aagttttggg tgaagaagat ggaactttct
    23701 ttaataatta ttttgatata actagtagtg gaaattttga aggtaaaagt attcctaatc
    23761 ttataaaaaa taaagaatat gaaagacata atgaaaagat agctgacctt agtaaaaagg
    23821 tatttgaata tagaaaagaa agaacatctt tgcataaaga tgacaagata cttacatcat
    23881 ggaatgcatt gatgatagtt gctttaacaa aggcatatag tactttaaaa aatgacatat
    23941 atttagagta ttcaaataag tgtcttaact ttataaataa taatcttgta aatgagtcag
    24001 gtagattatt agctagatat agagatggaa gttccgacta tttagcatat ttagatgatt
    24061 atgctttttt aatctgggcg tatatagagc tttatgagtc aacatttaat atgaaatatt
    24121 tagaaaaggc tttaaatttg aatgaaagct gtatcaacct tttttgggat tatgaaaaaa
    24181 gtggatttta tatatatggt aaagatagtg aaaatttaat agcaagacca aaagatttgt
    24241 atgatggagc tattccatca ggaaattctg ttcaattata caatcttata agacttgcga
    24301 aaattactgg agataataga cttgaagaaa tgtcatataa acaattaaaa ctgtatgtgg
    24361 ataatgtaaa gagttctcca actggctaca gcttttatat gctttcattg atgtttgaac
    24421 tttattctac taaggaaatt atatgtattt ttaaggaaga ttctgattta attgcattta
    24481 aagaattgat aagtgaaaat tttataccaa atgcaacttt tttagcaaag aaatacaatg
    24541 aagaaaacac tattataggt tttttaaata actatagatt gaaggatgat aagactagtt
    24601 attacgtgtg tcaaagtaat agttgtagtc aaccaattaa tgatttacaa aaattaaaag
    24661 atatgatttt aggagtagaa taatcataat agcgaaaaag gagatgcttt aaaataaaag
    24721 tctaatcatc tccttttttt gtacaaaaaa cagaaaaaga gttcctaaga acacctaatc
    24781 tatgtaatga ttgttttgtt aaaaaataaa aatgacatta tagttatata aaatattgta
    24841 ctataaaaaa gtggtattat agatgcgata gtattaatcg tttttattta ccctatttct
    24901 tctttttgca aattcttcaa gtgcttcaga tttaatttta tctatttctt catattccat
    24961 aaaattagca tcttcttcaa agccatcttg ttcttcacca ttaaaacgat acattttttt
    25021 tagtaaactc cataaggtct ctaattcatc tttggtaaat tcgtgaaata catctgccat
    25081 aaagtttatt ccagtcctac tacatgttac cataaccttt tttcctaagt ctgtaacttt
    25141 aacattaatt gctctcttat catgaggact tggaattaca tcaacatatc catttttttc
    25201 aagattagca actagtctat ttatattttg tttacttgta cccatttttc ttgcaatatt
    25261 atttaatgtt gtttcttcct ctggtaaatg aagaattgat aaaatagtca tatactgtct
    25321 tgaagtaagt ataccaaaat atttatctcc ttctatttgt attttgtttg taagggtaaa
    25381 aagagttgca tatgtttgat tcattaaaaa gagctctttt agttcatttg aataatccat
    25441 gaaatatatc tcctttattt ttagaagttg ttttgtcgaa aacagaatat catgaattaa
    25501 ttctaatgtc aatatggtgt caaaatatat taaagtatta cttttttatg taactattaa
    25561 ttaaattatt gtataattgt atgtaaaaac ttctatgtac caatgataat ttctatgagg
    25621 aattaataat tcttaaattt tttagaaaga ttttgacttg aaaatacttg taatataata
    25681 tataaattaa tatactgaat aaaatcaatc tggagggata attatgaagt gtacaaactt
    25741 tactttcaaa ggagaggaag gtttagatat atatacatat aaatgggaag atgaaaatat
    25801 aaaaaaacca aaggcagtta tccaaattgc acatggaatg gctgaaactg cacaaaggta
    25861 tgagactttt gccaaggtac ttactaaaaa tggttatata gtatatatca atgaccatag
    25921 aggtcatgga aaaactgcaa agataataga aaatgttgga catttagctg aaaaagaagg
    25981 atttagatgt cttgtagagg acatgtatac tttaacaaat attataaaga aagaaaatga
    26041 agatttgcca atttatctat ttggacacag catgggttca tttgcaagtc aaagatatat
    26101 aatggattac agtaataatt tatctggtct tatactatgt ggttcaaatg gaaagcaagg
    26161 aatcattcta aatcttgctc atctgataat caatcgtgag attaaaaagt atggaagacg
    26221 ttctaaaagt aataaaataa ataatttgat taaaaaatag cta
//
LOCUS       DAEQJM010000052        26210 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.052, whole genome shotgun sequence.
ACCESSION   DAEQJM010000052 DAEQJM010000000
VERSION     DAEQJM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26210
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.052"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(191..946)
                     /locus_tag="KRQ43_002641"
     CDS             complement(191..946)
                     /locus_tag="KRQ43_002641"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH2742988.1"
                     /translation="MLKVIINGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            1387..2376
                     /locus_tag="KRQ43_002642"
     CDS             1387..2376
                     /locus_tag="KRQ43_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBH2742989.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMIVLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVINATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(2647..3363)
                     /gene="dapD"
                     /locus_tag="KRQ43_002643"
     CDS             complement(2647..3363)
                     /gene="dapD"
                     /locus_tag="KRQ43_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBH2742990.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLNEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(3587..4336)
                     /locus_tag="KRQ43_002644"
     CDS             complement(3587..4336)
                     /locus_tag="KRQ43_002644"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH2742991.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDNEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(4403..5290)
                     /locus_tag="KRQ43_002645"
     CDS             complement(4403..5290)
                     /locus_tag="KRQ43_002645"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH2742992.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(5407..6408)
                     /locus_tag="KRQ43_002646"
     CDS             complement(5407..6408)
                     /locus_tag="KRQ43_002646"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBH2742993.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(6833..7714)
                     /locus_tag="KRQ43_002647"
     CDS             complement(6833..7714)
                     /locus_tag="KRQ43_002647"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH2742994.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            8037..9230
                     /locus_tag="KRQ43_002648"
     CDS             8037..9230
                     /locus_tag="KRQ43_002648"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBH2742995.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            9436..10554
                     /locus_tag="KRQ43_002649"
     CDS             9436..10554
                     /locus_tag="KRQ43_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HBH2742996.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            10685..10930
                     /locus_tag="KRQ43_002650"
     CDS             10685..10930
                     /locus_tag="KRQ43_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HBH2742997.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            10917..11663
                     /locus_tag="KRQ43_002651"
     CDS             10917..11663
                     /locus_tag="KRQ43_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH2742998.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            11948..12823
                     /gene="hslO"
                     /locus_tag="KRQ43_002652"
     CDS             11948..12823
                     /gene="hslO"
                     /locus_tag="KRQ43_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBH2742999.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPDDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            13214..14014
                     /locus_tag="KRQ43_002653"
     CDS             13214..14014
                     /locus_tag="KRQ43_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH2743000.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            14541..16781
                     /locus_tag="KRQ43_002654"
     CDS             14541..16781
                     /locus_tag="KRQ43_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH2743001.1"
                     /translation="MSNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNDIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSRDGEISEATKKKLSKLLIEDRCPICDGRRLNEGVYRSLI
                     NGYNIADLTSMQIDELAEVIKSINEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHVVDVGPKAGKYGGKVVYEGSYKNLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEIKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQRKNIIEVLEMSVLDAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            17195..18730
                     /locus_tag="KRQ43_002655"
     CDS             17195..18730
                     /locus_tag="KRQ43_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH2743002.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTAMTISGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGIGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNISDLKNVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVIVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSEVFKMVGDILTDKEMAKMNYDVENNNLEPREVACEFLNKK
                     GLL"
     gene            18746..19507
                     /locus_tag="KRQ43_002656"
     CDS             18746..19507
                     /locus_tag="KRQ43_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743003.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            19845..20713
                     /locus_tag="KRQ43_002657"
                     /pseudo
     CDS             19845..20713
                     /locus_tag="KRQ43_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            20907..21158
                     /locus_tag="KRQ43_002658"
     CDS             20907..21158
                     /locus_tag="KRQ43_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBH2743004.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            21270..22049
                     /locus_tag="KRQ43_002659"
     CDS             21270..22049
                     /locus_tag="KRQ43_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH2743005.1"
                     /translation="MNNTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(22184..22834)
                     /locus_tag="KRQ43_002660"
     CDS             complement(22184..22834)
                     /locus_tag="KRQ43_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743006.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIAFPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIDHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(22831..23334)
                     /locus_tag="KRQ43_002661"
     CDS             complement(22831..23334)
                     /locus_tag="KRQ43_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH2743007.1"
                     /translation="MKLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGRFGCWI
                     KTPSECVVKDYYSNMGKLINESDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(23383..23898)
                     /locus_tag="KRQ43_002662"
     CDS             complement(23383..23898)
                     /locus_tag="KRQ43_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH2743008.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKIDVEENHCIDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            24214..24705
                     /locus_tag="KRQ43_002663"
     CDS             24214..24705
                     /locus_tag="KRQ43_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2743009.1"
                     /translation="MRTIDIKGENMRELLKWVSIINRYNTNYIDRKLADIGINNSQYF
                     YVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVKDKRTWHLYPTE
                     KSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMNEEAKLEAKENG
                     RKI"
     gene            24689..26092
                     /locus_tag="KRQ43_002664"
     CDS             24689..26092
                     /locus_tag="KRQ43_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2743010.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
BASE COUNT         9715 a         3231 c         4333 g         8931 t
ORIGIN      
        1 aaaggactat aaaataataa acaatataat tccatatacc aataaataag ataatcttta
       61 agaaaaatga ttatatttaa aaggtaagca taaaatttat aaacttttag aatagaaatc
      121 tcaatcaatt agatattcaa attgatgaat atgaatacct aaatagattg agatttatta
      181 tgtacaaaac ttatcctagt atatctgaca ttttataaag tccagattgc ttaccaatta
      241 aaaatttagc tgcaactata gaaccgtttg caaatacttc atcagattga gaatgatggc
      301 ttaatgtaag aacttcatta tcacctgcaa atatgacatc atggtcgctg attatattgc
      361 cacctcttat agagtgtatt ccaatttcat ttggttttct tttacaatct ctaccatatc
      421 taccatgtgt attttcactt tcaggcaaga cttctctaat tgcattagct atcatagtag
      481 cagttccact aggggcgtct tcttttctat tgtgatgttt ttctatgatt tcaatatcaa
      541 aaccttctaa catctttgaa gcatccttaa ctaattttat taatatattc actccaagag
      601 atgtatttga tgataataat ataggaatgt tttttgatgc ttcttctatt ttatttaagt
      661 cattttcatc atatccagta gtagctaata ctacaggtgt attatttttt agagcatatg
      721 acaatattgg ctctaaagtc tcatgatgtg aaaagtctat tatgacatca gttttttcag
      781 ttacatcagt cattgttttg taaagctttg tatcactatg atgacctttt tcatcagcag
      841 acctagctac accacaaacc aactctaatt cattatcttt ttttacacat tctgctaaaa
      901 ctcttcccat tgttccatta tagccattaa ttataacttt caatataaat tcctcctatg
      961 aaattaataa aaatttgtta tatttctata agtttatttt atcactaata ttatttatat
     1021 aaaataatat tagtgataat aagcttacaa tttatcttac attaaaaaaa tttaagtgga
     1081 tttttcaaaa tatagataaa cttctttttc attgtataaa tgataaaaat atatttgact
     1141 tcatatcaaa aagagtgccc catgaactaa aaagttaatt ttgagatacc atattcatat
     1201 atcatatgat ttatttggaa atcaatatta atacattaaa ataactaaat acatgtatgc
     1261 ataaagatgt ataaaaaata tataaacata tagtattaat tttaaattca acaatttaat
     1321 tgttaaaagt gttattatta aattagaaat atcttaactt aatatactga gatgggagtg
     1381 atagatatgt taaaagaaga aaaaacttat caagagaaag acgcaaaagt attcaatgga
     1441 gtggcagctt tgataatgat tgtattattt ttagtagttt caataggtat catggttttt
     1501 gggatagtaa aacttgatag tggatttact ggaataggtt cacttatgtt aattttggga
     1561 cttgtattta tagtagtaga ttttatccta ttttttgggc taaaaatgat taatcctaaa
     1621 gaagctatag ttctagtttt gtttggtaac tattatggaa ctataaaaaa agaagggtac
     1681 tattgggtga atccattttg ttcagcaata aacccagcag tatcaagaat taatgtatcg
     1741 aaatcttcat ctgatgaaaa ggtagatata tcaactaatt caaggggcaa aaaagtatct
     1801 ttaaaaacaa tgactcttaa taatgaaaag cagaaagtca atgatttatt gggaaatcca
     1861 attataatag gagtggttgt aatttggaag gttataaatg caacaaaggc agtatttaat
     1921 gtggataatt ataatacatt cttatctatt cagtgtgatt ctactattcg taatgtttca
     1981 agactttatc catatgatgt atctgaagat ggagatgaaa aatctcttcg tggtagtagt
     2041 caggaaatag cagatagatt aaaagatgaa ttacaatcaa gggttgacat tgcaggaatt
     2101 gaagtgtgtg aagtgagaat tactcatctt tcttatgcac cagagattgc agcagcaatg
     2161 ttacaacgtc aacaagcaga ggctataata gcagcacgta aaaagattgt tgagggggct
     2221 gtaagtatgg tagagatggc attgactaat ttaagtgaaa ataatgttgt gactttggac
     2281 gaagaacgta aagcagctat ggtaagtaat ctgttagttg tgctttgtgg caataaagat
     2341 gcacaaccag tagtaaacag cagttctatt tattaaatta taaaaagttt aatagtttat
     2401 tacattgata tattgaaaaa ttgaaggaaa taaaaatact tgtcatcaag aaataaaaat
     2461 gatataagaa tgaataagag aattgtaaaa aaataaaatg attataaata aaagataaaa
     2521 atattataaa aaagagggtg cctctgatga attaaattca tacagagaca cctttttaat
     2581 taatttttta aattagtata ttattgttta attaatcttt ctaattaata atatagtact
     2641 atttaattag tctaaatttc taaggtcttc cataagctta gttttgtcag ccgttttttc
     2701 atctttcatt tttataactt tagcaggaga accagcaaca acggcaccag cttctacatc
     2761 agtagttaca acagcaccag ctgcaacaac agcaccttta ccgattctaa caccttcaag
     2821 aataactgca ttagctccta ttaaaacatc atcttcaact ataacaggag tagcagaagg
     2881 tggctctaaa acaccagcaa caacagcacc agcacctaag tgaacatttt taccaagagt
     2941 tcctctagct ccaataacag cattcatatc taccatagaa ccttcaccaa taacagctcc
     3001 tatatttata acagctccca tcattacaac agcatttttt tctatagtaa ccatgtctct
     3061 tattattgca cctggctcaa ttcttgcatg ttcatttaaa gtatttttta gaggaatagc
     3121 agaatttctt ctatcatatt ctacatgagt atctgttata tcattcccat gtttatctaa
     3181 tacttccatt atatcctcat agtcacctac aaatatataa gaaccattac ttccaaatac
     3241 cttaaattta tcagttgatt ggaagtgtaa agagttagta tttacatata ccttaacagg
     3301 tgttttcttt ttaacttctt ttatatacct tgctatttca taagcatcgt ttaaatttac
     3361 catttgttaa ttctccttgt atttcattat atttctttta ttatatactt atttgtcaat
     3421 tttagtatat acttacttct tattatttat attttatttt agttagtttt tattgtatag
     3481 acatagtatt aaataaattt attatatatg tttgatttgt attgcgtatt attatatcta
     3541 tattgcatat gtttaattta tattgtgtat tattatattt atactattat cccaacatgc
     3601 tgtccatatt ataaaatcct ggtttttgct taactaagta tttggcagca gctatagaac
     3661 cacttgcaaa gataccacga gattgagctt gatggcttat tgtaagaacc tcattgtctc
     3721 cagcaaatag agcatcatgt tcgccaacaa tatttccacc tcttatagca tgaataccaa
     3781 cttcatttgg ttgtcttttt gcactacgac catatctacc ataattattt tcaacgtttg
     3841 gcaaaacctc ttttatagcg ttagcaatca taacagctgt gccacttggg gcatctactt
     3901 ttctgttgtg atgtttttct attatttcta tatcaaatcc ttctagtaat ttagctgcat
     3961 ctttaaccaa ttttactaat acatttacac caagagacat attatatgat tggaatacag
     4021 gaataacttt agccgcttca cgtattttgt tcatttcgtt atcattatat ccagtagtag
     4081 caattactaa aggtgtttta gtctttaaaa cgtaagataa gatattatct aaattagagt
     4141 gatgagaaaa atctataact acatcagctt cctcaactat agtactcata tcttcataaa
     4201 ttttaaggtc gccttcatag ctatccagac ctctagctgc aacacaaacc aattctaatt
     4261 cattatcttc tcttatagta tcggctaaaa tcttacccat ttttccatca taaccagttg
     4321 ctataacttt taacataatt tcctcctatg attaagggct aacttttgac caaacttact
     4381 ttttaccatg cattaatctt tactatgcat taacttttag tccaaagtta actaattctt
     4441 tctttaacac ttctaaattt gctgggtcca tttctgctag aggtaatctt aaatctccaa
     4501 cattgaatcc caataaattc attgcagtct taactggtat aggatttact tctataaata
     4561 aagctgcgat tagagcatcc ataccaagtt gtaattttct agaaccttca atatcgcctt
     4621 caaagaattt agctaccaaa tcgtgagttt cttgagggca aacattagca agtactgata
     4681 taactccttg acctcctaaa gataataaag gaagtatagt atcatcatta ccagagtaga
     4741 tagcaaagtc atctggaact aaactagcta tttctgcaac ttgtcctagg tctccactag
     4801 cttcttttac agcaactatg ttatcaattt tagcaagttc aactataagg ctaggactta
     4861 tatttacaca agttcttcca gggacattgt aaagtataat tggaagttta acactgttag
     4921 ctattgtttc aaaatgacgc ttaagtccag ctttattagc tttattgtaa taaggtgtta
     4981 ttattaatag agcatctact cctaattttt cagcttcttg acttaagtta actgagtgca
     5041 tagtatcatt agaaccactt ccagctataa caggaactct tttattaact ttttcaacaa
     5101 catacttaat agtagcaagt tgttcttcat cagtcatagt attagcttca ccagtagtac
     5161 cacaagatac tatagcatca gtaccattag ctatttggta ttcaactaat tcacctaatt
     5221 tgtcaaaatc aactttgtta tcctttgtaa atggtgtaac tagagcaaca gcagaacctt
     5281 taaatatcat ataaaatcaa tcccctcttt tttatttttg tgttttatat tacagttact
     5341 tctaatgctt gtttttgagt tactattaat attttacaaa attatatatt tatacaagtt
     5401 tgtatattat actaaatcgt atgataaagc catttcagct atttgaattg cgttagttgc
     5461 agcacctttt cttatattgt cagcaacaac ccaaagattt acaccattat caacactaaa
     5521 atctcttctt attcttccaa caaatacttc atctctatca tcaaattcta cagcagttgg
     5581 atattcgttt ttagcaggat tatcaactac tacaacacct ggagcttctt caagtgtttt
     5641 tactaaatca tctaactcaa atggattgtt aaactcaaca tttatagatt cactatgacc
     5701 attttttact ggaactctta cagtagttgc agttattttt aaatcatagt tatcaagtat
     5761 tttcatagtt tcatttacca ttttcatttc ttctttagtg tatccatttt cagtgaatga
     5821 atctatatga ggaagacagt tgtaagagat ttgatgaggg tagaatccag taggattacc
     5881 gttcattcct ttctctaaat cttcaacacc tttaacacca gaaccagata cagcttggta
     5941 agtagagtaa acaactctct taattttgta tttatcatca agagctttaa ggggaaccat
     6001 agcttgtata gtagagcagt taggattagc tattataccc ttatgatttt ttatggcttc
     6061 tggattaacc tcaggaacta ctaaaggcac atctggattc attctccatt gactagagtt
     6121 atctactact aagattccat ttgaagcagc tattggagca tacttttcac taatacttcc
     6181 accagcagag aataatgcta tttgtatgcc tctatcagta aatgaagttt cctttaattc
     6241 ttctactata tattctttac cacaaaacat tactttagaa ccagctgatt tagaagaaga
     6301 gaataaaaat agattttcta ttggaaaatt tctttcttct aatactttta aaaatgttct
     6361 acctaccatt ccagtagcac caactattgc tacatttact tttttcatat aaattcaccc
     6421 caattttaaa ttattaaaac attattttat tttagttata caagtaagat atgttaatat
     6481 ttttatatat ccaaaaactt taatattata ttaacaactt taattatata caaaaaacgt
     6541 acaaaggtat actttgtacg tctaatttat cactcaaagt aaaccctgta gctcatcacc
     6601 tacaaaaata agtgacagta ttacacatgt tatgtgcaat cccagaaaat attattgcaa
     6661 gaaatatttt cttcggctgt aaatcctttt tccaatcatt aacacctgcc agctactatt
     6721 ggatactctt agttacagct acctctaccc taggttaata ggatattaaa atttgattat
     6781 tctaataata atacatattt aagaaaaaat caacttattt atataaatat tgctaaaact
     6841 taaatccaaa atttgtcaat tcttgtttta acacattaag attagtttct tccatttcag
     6901 ctagaggaag tcttaaatca ccaacattaa aacctaaaat gttcatggca gttttaacag
     6961 gaactggatt tacttctata aataaagcag caattaaagc atccatatca agttgtaatt
     7021 tttttgagcc ttcaatatca ccttcaaaga atttagttac taaatcatgt gtttctttag
     7081 gacatatgtt agcaagtaca gagataacac cacttccacc taatgataat agtggtagta
     7141 tagtatcatc attaccggag tatatagcaa agtctttagg tactaattta gctatttctg
     7201 caacttgagc taagtctcca cttgcttcct tcacagcaac tatattatct attttagcaa
     7261 gttcggccac aacagatggc tttatattca ctttagttct tcctggtacg ttgtataaaa
     7321 taattggcaa cttaacgcta tttgctattg tttcaaagtg aagtttaaga cctttctcat
     7381 tagtcttatt atagtaagga gttattatta aaagaccatc cacccctaat ttttcagctt
     7441 cttgactcat atgaacagac aacatagtat tgtttgaacc agtacctgct ataacaggta
     7501 ttctcttatt aactttttca actgtatatt ttattacagc aaaaatttca gattcactca
     7561 tagtagtcgc ctcacctgtt gttccacaaa caactagtgc atctgtgcca ttctcaatgt
     7621 gatattcgat taattcacct aatttttcaa agttgacatt attatcctct gtaaatgggg
     7681 taactaaagc aacagcagaa cctttaaata acatataatc aaatctcctt ttttatctaa
     7741 atttaatttt ttaagtacaa taataattat agtacaaatt aattaatttt aataggtata
     7801 gttaatatct taactgttta aataagatat ttatattata ttaatattag aaaaatttta
     7861 aataaatgtt ttattctcaa aatatgcata ttaatttaat aaaatatacc aaaatggaaa
     7921 taaaaaataa attttatgag aatttaataa ctaataatta atatatttag gttataataa
     7981 atatgtgcgt aaaatctaac aataagcaat aataccgtaa atttaggagg aataatatgg
     8041 atactttaaa ggaacttttt aaaataggaa gtggaccttc aagttctcat actatgggac
     8101 cacaaagagc agcagagaga tttaagaatg aaaacccaga tgcagaaagt tttagagcaa
     8161 tattatatgg tagtttggca gctacaggga aaggtcactt aactgactat ataattgaaa
     8221 aaactatagc acctaaaaaa gtcgaaattg tttgggaaga agatattata aaagattttc
     8281 acccaaatgg gatgaagttt gaagctttag ataaagataa aaatgtaaca gctgaatgga
     8341 ctgtatattc tgtaggtgga gggactatag cagaagaagg tcaaagaaac agtaaaagca
     8401 atagtatata tcacttagat actatggatg agatagtaaa atggtgcaaa gaaaataata
     8461 agactttggt agattttgtg ttggaatgtg aaccaaaaga cataaaagat tatataaaaa
     8521 ctataaaaga tgctatgaga aaatctattg atgatggact aagtacagat gaaataatac
     8581 caggcaagtt attattaaaa agaagagcaa gtacatttta taatgcatat aaaaaagata
     8641 agagcttctc aacacttgta tatgcatatg cactagcagc ttcagagcaa aacgcttctg
     8701 gtaatataat agttacagca ccaacttgtg gttctgctgg agtaatacca ggaatattct
     8761 ttgcaatgca ggatttctat aattatgatg acgaaaaaat aattgaagca ctacttgtag
     8821 ctggaataat aggtaatata ataaaaacta atgcttcaat atctggagca gaggtagggt
     8881 gtcaaggtga agttggagca gcttgttcta tggcagcagc agcagtagca tacttaaaag
     8941 gtggaactat agaccatatt gaatatgcgg cagaaatagc acttgaacat catttaggaa
     9001 tgacttgtga ccctgtatat ggatatgttc aaattccatg tatagaaaga aatgcaatgg
     9061 cagctcaaag agcttatgat gcagctaatt atgcattatt aactgatggc tcacattctg
     9121 tctccttaga ccaagttgtt gaaacaatga aagaaactgg tatagatatg atggataagt
     9181 acaaagaaac agctaagggt ggacttgcta aacatttctt ctcttgctaa aaataaaatt
     9241 ttccaataat aattcctctg ttttgattta tgaaacaggg gaattattat taatggtgaa
     9301 ttatttaata atgcaaaata tttttatatt caatttagct ttttattttt aattagtata
     9361 acatgctata taatatttta attataaaga aatatagaaa tattttttaa taaattagaa
     9421 attggaggag attacatgag agaggcatca tatttacaag aacaacttta taaacatagg
     9481 aagtcattaa atcctattgc agagattggg agaaaagagt ataagacttc aaaatatata
     9541 agagattatc ttgataaatt aggaattgag tatgaagttt atttagaaac aggtatagta
     9601 ggtgtaatag aaggtaaaag acctaaaaaa gatattgctt ttagagctga catagatggt
     9661 cttcatagtg aagaaggggt aaaacattta tgtggtcatg atggacatgc tactatatta
     9721 cttggattaa ttgagtattt aaatgataat aaagaagact taaatgataa tatagtattt
     9781 atattccaac cagcagaaga aggtcctggg ggagcaaaag ctttaataga tgaaggagtg
     9841 cttagaaaat acaatattga tgaaatatat gggcttcata tatatccaga gttaccagaa
     9901 ggttatgtag gtacaagaga aggctatttt atggctcaaa taggagatat cgacatagaa
     9961 atagtgtcta aaagtggaca tggggctatg ccacaaaatg gtattgatgg tatagtgata
    10021 gcttcaaact ttgtaagctc acttcaaact atagtgtcta gaaatataag cccaatagac
    10081 aatgcagtgt tgactattgg tagaattgaa gggggagcta gaagaaatat aatagctgaa
    10141 aatataaaga tggaaggtac tatgagatgt ttcagcccag aagtgtatga gaaaatgaag
    10201 cttagagtta gagaacttgc tagagggttt gaattggctt ataactgtaa ggttaatata
    10261 aatattatag atgattatat tgctgttaaa aatgacaagg atttgtatca agagtttgta
    10321 gaggctattg gaagtgatac tgttgtagag ttagagccac ttatgatatc agaagatttt
    10381 tcttattatc aaaaagaagt tccaggatta ttttttatgt tgggttcaag aaacgaagaa
    10441 aaaggatttg taaatggtct tcataatata aactttaatt ttgatgaaaa gatatgtgta
    10501 aatgcattga atgtttattc aaaattatta aaatacaaag aagcaataga ttaggaagat
    10561 aaattataaa gattaaaaag cataaatacc taaatttaaa aaaaatgtat taataaatac
    10621 cccttatata tttgtataaa tttattttaa ttgacaaaaa tacaaataag aaggggtgat
    10681 ttttttgaaa gaaaaagtac aaagagaaaa gaagataact aatggcaaga atactaaaat
    10741 attgacaaat gatgatataa tgaaatatga gatagcctca gaactaggtc ttatggataa
    10801 agttggtgaa cgtggatggg caggacttac agctaaggaa gcaggaagaa ttggaggtat
    10861 gcttacatca cgcaaaaaga ggcttaaaaa gattgtggag gagcagaata aaaaggatga
    10921 gtcaatatag tgattttgcg tttgtatatg atgaacttat gaatgaagtt gattataatg
    10981 gttgggttaa atatatagaa gatataatag atagtgaagg tgtaaaagta aaaaatatat
    11041 tggaattggc atgtggcacg ggtaatctta caattccatt gactaaaaaa aattacgata
    11101 tagctggtat agatatatct gatgagatgc ttagtgtagc aagagaaaag gcagaaaaag
    11161 aaggagtaga attagtttta cttcaacaag atatatcaga gcttgatttt gaaatatctg
    11221 atttggactg tgtgctttgt gcttgtgatg gatttaatta tataacttat gatgatgatt
    11281 tggaaaatgt attttcaaag acatatgaat tattaaagaa agatggaata ttcatatttg
    11341 atataagttc tttttataaa ttagccaaca tattgggaaa taacatgtat ggagaaaata
    11401 gagaagatat agcgtatatg tggcaaaatt actttgatga agaagagaat ctaattgaaa
    11461 tggaacttac attctttatt aaagatgaat gtggaaagtt tgaaagattt gaagagatac
    11521 accaacaaag agcatatact gaagatgaga tagttgatat gcttgaaaaa tctggattta
    11581 aggatataaa atattatggg gattttacat ttgacaaacc cagtgaagaa agtcaaagaa
    11641 tcttctttgt atgtaaaaaa taagatattt ttgactatat aagataatta ttaaaaataa
    11701 ccatgatata aaaatataga aaatgcagtt ttatagatta aaagtaaagt gatgatactt
    11761 tatgactttt attttctaat aattataaag ttctatagat aaaaattaaa atataataac
    11821 tattgcttag taaaattaaa ataaaatggg ttttgcccaa ggttaatata gataagtact
    11881 tatagattaa aattaaggta gtaatataat aaaaataaga caattaacgg gacatggagg
    11941 aatattaatg agagattatg tactaagagc gacatcagga aatggtcaag ttagagcatt
    12001 tgtcgcaact actagaaata cagtagaaga agctagaaga ttacatgaaa ctacaaaagt
    12061 agcaacagca gcacttggaa gaacattaac agccacatct ataatgggat taatgatgaa
    12121 aaatgatagt gataaattga ctgtaataat aaaaggtgga ggtccaattg gaactattat
    12181 cgccacatca gattctaagg gaatggtaaa aggatatgta ggaaatccac aagtagaggt
    12241 tgaagactat ccaaatggaa agttaaatgt agcagcagca gtaggtacag aaggtgttgt
    12301 aaaagttata aaagacttag gtcttagaga accatataat gggacttatc cattggtaag
    12361 tggagaaatt gcagaagact ttacttatta ttttgctgta tcagagcaga ctccatcagt
    12421 agtagcttta ggtgttctta caaaagaaga tgaagtagag tttgctggag gatttatagt
    12481 tcaattaatg ccagatgcag aagaagagac tattgctaag ttagaggaaa atgtagctaa
    12541 attaccttct ataactaaca tgttaaaaga aggaaaatca ccagatgata tattaaatat
    12601 tgttttggat ggtttggaac ctaaaatact tgatacctgt gaagtagggt ttatgtgtga
    12661 atgttcaaaa gaaagagtaa aaactgcttt ggttgcaatt ggtaaaaaat cattggctca
    12721 gataatagaa gaagataaaa aagcagaagt tggttgccag ttctgtaata agaagtatat
    12781 gtatagtgaa gaagagttgc ttgaaatttt aaaggaaatg taggctataa aaatagttgt
    12841 attgatataa gtaatgttat agtgatatag taaagtcgta ttgatatagt aattaaagta
    12901 taatttatta ataatagaca tatttatatt aaaaaataaa tttaataaat ttttaagctt
    12961 aataaatttt aagaattaag aagctttctg gctgtaatat ttgcaatgtt gcagttagaa
    13021 ggctttttta ttttattata gttcgtgtca aagattgtat gaaacaataa aatattgtaa
    13081 aataatttgt atatttagac ctgattgaca caaaggttta taagatattt gagttgatta
    13141 tacgaaattc tatgaagtag taaccctgtg actttaatca tgggaggttc agaagaagga
    13201 gaaaatttta aatatggaaa gtaaaacgaa gtacatagga ataagtatat taatattatt
    13261 gatgatattt ttaattgcaa agaattttaa cggaaaactt gaaataccta ttcctgagag
    13321 taatagtaga aaatttaaat cagcagcagt gttttatcct caacatcaag atgatgaggt
    13381 tttatgggga ggaagtgcca ttgtagatgc tataaaacag tgtggtgttg ataatgtata
    13441 tgtggtatta gtatcagatg gttctggagt taacgttttc aaagctaaca caaaatttag
    13501 aaacttaact aggaagcaaa aggaagagct tagaaataat gagtttaaat cagctttgag
    13561 agagcttgga gtgaaacctc aaaatgtgat tatacttgca gatatagata aaaaggaagg
    13621 cacacattat gaattaatgg aaaagactat attggatttt gaacataagt ttaaaggcaa
    13681 tgtgacccat atagcccatc actataagta tgatgaccat ataatgcata gaaagaatgg
    13741 ggaagtttta aagaaactta aacgtgaagg taagataaaa gatgacttgt attttgttaa
    13801 gccaaaatat gtaaagtata taccaagaaa tgaaagagct atctataaag caatggattt
    13861 tgatgactac aataaggtta agagtgcttg ttatgaatat aaggttgtaa attcaaagcg
    13921 taaaatgtat ggtataggat atatttcggc acatagttat tttgaacatc ttctaaatga
    13981 ccctgaactt acgtctgtat taagtgaaga ttaatttctt ataagtagta agttatgttt
    14041 gataagttga ttggaatttt ctatagtttt gaaggtattg gaaatttagt tttatttaaa
    14101 gatttaaaga tagaggtttt taatgtttaa aattttaaag ttaagttgaa taattgtata
    14161 gaattatttg tgaaagaaga aacagtgtaa aacatagtat cttatttatg gttttaaaat
    14221 cataggcaag atactttttt tatgtaacta ataccatttt gaggttatta acttaagaat
    14281 tttatataat ttaacactca tatataatga tgatatttag gtagaataga tgcaattacg
    14341 cttaaataaa ataactgtat tttttataaa aatcaaaccc tacactatac taccagataa
    14401 aatctacatg ctataatttg acctgtgttt ataaaaaaag gagtaatcta ataaaatagt
    14461 atttcactta tgtataacta acaactatta ttacgatttt ctctaaataa tttaaagaaa
    14521 aataatgcag gaggtaaaat atgagcaatg aatttataat tttaaaaggt tgcaaagaga
    14581 ataatttgaa caatatttcc ttaaaaatac caaaaagaaa aataaccata ttcacagggg
    14641 tgtcgggttc tggaaagtca tctattgtat ttgagacaat tgcaaaagaa tcacaacgcc
    14701 aactaaatga aaggtttagt acatttgtaa gaagtttttt acctaagtat ggagaggtta
    14761 aagctgattg tatagaaaat ctgtcaacac caattatcat agaccaaagt agacttggtg
    14821 gaaattcaag gtcaacccta ggtactatta cagatgtaaa ttccttttta agagctttat
    14881 attcaaggtt tggtagtgag tatataggta atgctaatat gttttctttt aatgatattg
    14941 atggtatgtg cccacactgt catgggcttg gaaaaaagct agttcctaat atgaaccaaa
    15001 ttcttgatat gaataaatca ttaaatgaag gtgctatatt gctttcaggg tttggagtgg
    15061 gttcttggca ttggaatata ttcgctgaat caggattttt tgatattaat aagaggatat
    15121 gtgattattc agaagtagaa ttggaaaagt ttttgcatgg taaagcagaa aagattaaga
    15181 tagaaaatgc tggtcaaact aacatgacat atgagggatt aatggttaaa tttaatcgtc
    15241 tatacttaag tagagatgga gaaatatctg aggctactaa gaaaaaattg agtaaacttc
    15301 ttatagaaga tagatgtcct atatgtgatg gaagaagact taatgaagga gtatataggt
    15361 ctttaattaa tggttataat atagcagatt taactagtat gcaaattgat gaattggctg
    15421 aagttattaa aagtataaat gagccagaag cacaaccttt aattaaagga ataatagaaa
    15481 agttaaacag tatcatagat ataggtcttg gatatttaac actggataga gagacatctt
    15541 ctctatcagg aggggaatct cagcgtataa agatggttaa gtatttaaat agtaatcttg
    15601 ttgatttaat gtatattttt gatgaaccaa gtgtaggact tcatccaaaa gatgtgtata
    15661 aattaaataa tcttttaaaa aaattgcgtg ataaagggaa tacaattata gttgttgaac
    15721 atgacccaga tgttattaag attgcagacc atgttgtaga tgtaggacca aaggcaggta
    15781 agtatggtgg aaaagttgtg tatgaaggca gttataaaaa tctacttaca agtggtactt
    15841 tgacagggaa tgctttaagt aaatttcttc ctattaaaga aagtgtaaga gaacatagtg
    15901 gatatttaga aattaaaaat tgtaataaaa acaatttaaa aaatgtatct attaagatac
    15961 ctaaaggtgt attgactcta gttactggag tagcaggagc aggtaaaagt acgttgatta
    16021 aggatgaatt tttaaagcaa aatcctagtg ctgtacttat agaccaaagc cctgtttcag
    16081 caaattcaag gtcgagtttg gcaacatata gtggaattat gaacaacata agaagcatat
    16141 tttcaaaaac aaatggcgta aatgcttctt tattcagttc aaattcagaa ggagcttgtg
    16201 ataactgtaa gggttctgga atagtagaaa tgaatcttgc ttttatggag agtataaaga
    16261 gtacctgcaa tgtttgtgaa ggtaaaaaat ttaaaaaaga agttttagaa tataggtttc
    16321 aaaggaagaa tataattgaa gttcttgaaa tgtctgtttt agacgcaatt gagtttttta
    16381 atttaaaaca gattaaaacg aaattacaat gtattgaaaa aatgggtatt ggatacctta
    16441 ctttaggaca aactcttgat actttgtctg gaggagagtg tcaaagatta aagcttgcta
    16501 gtgaattaaa taaggaaagt tcagtgtata tattagatga accaacaaca ggtcttcata
    16561 tggctgatat tgagaatttt ataagtataa ttgaagagat tgtagataat ggaaatacgg
    16621 tcataataat tgaacacaat atagatgtaa ttaaaagagc tgattggatt attgagctgg
    16681 gacctgaagg agggacaaaa ggcgggagag taatatttga aggtatccca aaacaattat
    16741 gtaacaataa aatatcatta acagcaaaat atatagtata ataaataaaa tataataaaa
    16801 ttataatgat attttaataa atataatggg tatataaaat gataattaaa cttaacagta
    16861 ataaataatg tgagaaatat tcaaatttaa ttaaataaag tgtcagaaat ttgtttaaat
    16921 tttagtattt taacgattct gacctttttt cttattttta tggagagtat cgaagatgga
    16981 gtctctaata gttacttttt tgtgtctact tgcaagtttg attaaaaaat ggctatacac
    17041 acttgtgact tcagtcatgg gaggttcaga ttataatctt aatatataat ttgtgaaata
    17101 atttgatgac gatttgctga tgtataaaca ataaagatta actacattaa aatttaaatc
    17161 ttgttaagta aaacttataa aaggagagag atggatgata aatgatattc taaccttatt
    17221 atctgaaaga agtgattttt ttataaagct atccatagaa catttgatga tttctattat
    17281 ttctataata attgcgattg ttttgggtgg tataattggt attattgtaa gtgaatttca
    17341 taattcttct aaacctatat tgggaactat caattttcta tacaccattc catctatttc
    17401 tatgctagga tttctgatac cattttccgg aattggaaat actactgctg ttattgcact
    17461 taccatttat gcattattgc caatggttag aaatacatat actggaatta ctaatgtgga
    17521 taaaaatatt cttgaagcag ctaggggaat gggcagtaca gattttcaga tattgtataa
    17581 aataaaactt ccattagccc tacctgttat tatgtctggt attagaaata tggtgattat
    17641 gacaattgca ttagctggta tcgcttcatt tataggtgct ggaggcctag gtgtagccat
    17701 atatagagga atcacgacaa ataacacagc aatgacaatt agtggaagta tacttattgc
    17761 tctattagct ttaatatttg attttatttt agggctggta gaaaaatttt ttcaacgaaa
    17821 aagaaaaaag aaaaatagga aaaaagtttt tgccattcta ggaagcctta ttcttatagc
    17881 aactatcttt acgtcttatt tatttaatcc ttcaaagact caaactattc atattgctac
    17941 taaacctatg actgaacaat atattcttgg tgagatgttg gatattttaa ttgaaaaaaa
    18001 cacaggtcta aacgtggaaa ttacacaagg cataggaggg ggaacatcta atatccagcc
    18061 agctatggag aatggagaat ttgacattta tccagagtat acaggtacag gctggaatat
    18121 ggtacttaag aaaaatgaat tatatactga aagtatgttt agtaaactac agtcggaata
    18181 caaaactaaa cttaaaatgc aatggactgg tatgtatggt ttttctaata gctatgcatt
    18241 agcagttaga aaagaagttg cagataaata taatttaaaa aatatatcag acttaaaaaa
    18301 tgtatcttct aaattgacat ttggagctga atatgacttt tatgagagag aggatggata
    18361 tactccattg tgtaatacat atggactgaa ctttaaagat acagttgatt tagatattgg
    18421 attaaaatac caagctatca atgaaggtaa gattgacgta atgcctatat ttacaactga
    18481 tggtcagtat agtgtttcag atgttatagt tctaaaagat gataaaaatt tctacccatc
    18541 ttatcaatgt ggaaatgttg ttcgtttgga agtattagag gaaaatccag aactatcaga
    18601 ggtatttaag atggttggag atattttgac tgataaagaa atggctaaaa tgaattatga
    18661 cgtagaaaac aacaatttag aacctagaga agttgcttgt gagtttctga ataagaaagg
    18721 tcttttataa attggaggaa atataatgac acctattata caatttaaaa atattaaaaa
    18781 acaatataat gataaaacta taatagataa tcttaattta gatatagaaa aaggagagtt
    18841 tttgactgta attggttcgt ctggttctgg taagacaaca ctcttaaaaa tgattaatgg
    18901 tctgattttg ccagatggag gaaatatttt gataaaccaa acagatatca aaaacgagga
    18961 cttaattaaa ttaagaagaa gaataggata ttgtgtacaa ggaagtgttc tttttcctca
    19021 tatgactgtt gaagaaaata tttcatatgt accaaatctc ctaagtaaaa agaataaatt
    19081 agaagtaaaa agtgctgtaa acaagtggat ggaaatagtg ggattgccaa atgatatgaa
    19141 agtgcgttac ccatcagaat tgtcaggtgg tcagcaacaa cgtgtaggga ttgcaagagc
    19201 tttagcttct tctccagaaa ttttattaat ggatgaacct tttggtgcag ttgatgagat
    19261 tacacgaaag caattacaaa aagagataaa agaaattcat aaaaaaacag gagttacgat
    19321 tatctttatt acgcatgata tttatgaagc tttgattttg ggaacaaaga ctttggtatt
    19381 aaatcatgga gttgttcaac agtatgatac tcctgagaat attttaaata ctcctgctaa
    19441 ccaatttgta gaccagttat tgaatataag aaaatctata atagatgatg ataatttaaa
    19501 agaataaatt taaatttaaa atcaaattgt tgtgataaaa actattgatt tagagctaac
    19561 ttcaagttgt atacttgaag tggaaaagtt agattaaggt atagaagaga atttagcagt
    19621 tggctgtaga cgaggtaact gctgaaggtg ctttcaataa atggctagaa cctgtatcta
    19681 ttgaagatta taataaattg aaataagaag ctcaatatac agagtagata ggcacttcaa
    19741 atagaagtgt cttttgtgtg ccataaaata aatcaaaata ttagcaaaga atgtgaaaaa
    19801 caaaataaaa taatatgcta tctttaaaat aggaggggtg ctatatggat aacaatttga
    19861 ttaccattga aaaaacttta gattatatag aaaaacatct tttagatgag atgttagatt
    19921 taaatgtaat ttctaaagag ataggctatt caaagtacca tttacataga atgtttacat
    19981 cagttgtcgg atttagtata cataattata tacaaagacg tagactaact gaagcagcaa
    20041 gaatgctcat ttttacagaa aaaccaatta ttgaaattgc tttaatctcg gggtatgaca
    20101 cacaacgttc tttttcaaca gggtttaaaa aaatgtttaa gcatagccct aagtttttta
    20161 gaaaacatca agatttttta ccactacaat taaaatttga tattaataat agaaaaaggt
    20221 tacatggagg tatggtttta gatgttaaaa aagttaattg tacagatata aatattgttg
    20281 gctattctgg taaagtaaaa aaaggatttc atgttattgg aaaatgttgg agggatttgc
    20341 ataaaaataa agagttgata gaaaacaagg tagacttgga ttttttaatt ggagttaatg
    20401 attatagtaa ttttaaagaa attgaaaata atcctacatt tacatatatt gcaggtgttc
    20461 aagtagctac ttttggtaaa ttcctaatgg aatggaaaaa ttcgtattac cgaaaagtaa
    20521 ttatattgtt tttactttta ttgggaaaaa tgaggatagt atgcaaaatg ttgtagaata
    20581 tatctatcaa gaatggttcc ttaattcaag ttgccagttt aatgaaaata atttatatga
    20641 ttttgtaaaa tacggagaaa aaactgataa gaatggtttg agtgaaattc agttttgggt
    20701 tccaatcatt taaaagaagg gattatgtat aaagtaggtg gatttatata ggcaaagttt
    20761 tataaaagta tgtatttata aataatttat agtctgtagg aaagaaatag ttttactata
    20821 agattatgat aaaatacaca atactatgat aaaatagtac taaataatag atttaatttt
    20881 gcaaaggata aagtgtttta ataaaaatga atgtagaaaa cgaattactt aaaaacctag
    20941 atagattgca tacaacagag ttaggcgttg taagaattaa gaaaaatctt tctttggaga
    21001 caaatgatgt agtgaactgg tgtaaaacta aaatagaatc tccaaatgcc attattaata
    21061 gaaagggaaa aaactggtat ataagtgtat atgattgtat tataacagta aacgctcaca
    21121 gttatacaat tattacagct cataaagaaa agaaatgaat tgaaaaatac aaaggtcaaa
    21181 agcattttcc actgtttgta gtacctatga agaagtatat aaaataatat tacttttgaa
    21241 taataattta aattttggag gttgaaaaaa tgaataatac tgtaaaagaa aaattggcag
    21301 agtcactaac ttctgatact actgatattt taccttattt gccttattta ttacaagatt
    21361 tttgggaatt aggaagttca ccagaacaaa tgttacaatt atttagaaag catatacctt
    21421 ttaatgagga tacaaaagtt ttggatttag cttgtggaaa aggtgctgta tctgtgaagc
    21481 ttgcaaaaga gttgaatata catatcaaag gtattgattt gatacctgaa tttattgatt
    21541 atgcgagaag aaaggctatt gaatataagg ttgatgcttt gtgtgatttt gaaatgaatg
    21601 atgctaatag ttctgtaaaa attgagcacg attatgattg tgtgattttt ggagctgtag
    21661 gggatatttt aggtaattat aaagaaacta taagtaagct attacctaca ataaaaagta
    21721 aggggttcat tttaattgat gatgcatatg tagtagataa atctacaaat gaacagctta
    21781 attttgagag ggtgtatccc acttacaatg agtggtgtat attgttcaaa gaattaggtc
    21841 tgaaactaat tgaatgtata ccatgtttag aacttgaaaa tgatgttgaa gaggaaatga
    21901 actggattat aactcgtgca aatgagctaa ttaaaaaata tccttctcaa aaagatatgt
    21961 ttgaacaata tgttattagc caaaaaaatg aatatactga tttacagcag gaccttgttg
    22021 gagcaacttg gattttacaa aaagaataag ataaatatta gactagataa tcaatgttgt
    22081 agtgaattat cccatgtcta gtgaatataa ataacataaa aaaccgtcaa gatgaatagt
    22141 ttattcgtgc ttgacggttt ttagtatttg ttgaagtaaa attttatttc tttagtatat
    22201 cacttttagt caatccattt gatttagctt gagtattcca ttgatgattc cccataagtt
    22261 tatataggaa tctagggaag ttaggtgaaa taaaaatagt acttttgttg gaatcatcta
    22321 tatgtatatt atcactaagt atattttttg aaagttcttt taatgcaatt cctaaatctt
    22381 ttttaggtcc tttacccaaa ggtacggatt ctagtgaacc aaacatctcc ccagctccaa
    22441 ttccaatacc ttgaacccat gtaaagttga tttttttgca ccaatgatct atcatttgaa
    22501 ttgccaaatg attatgttca ccttcattga atccacagtt aactattgca tacactggaa
    22561 taggtttttt attttgtgtt tttaaaaatt tttcacattt ctctaaaaaa tgaagtaaat
    22621 gagatggaat accatctaca taaagaggaa atgctattat taatctatca caattaagta
    22681 tggcattaag agcgtcagga tacttagatg tgctatctac tttaaatgta aaaactttat
    22741 tatcattttg aataagttgt tttaattcag ataaaaaata ctgtgaatta tttttattta
    22801 cttttggact accatttatc attactatat tcatatggat tcacctctta tatcctgtat
    22861 attttcatag aaacaaacag agtgttcttt tatattgaaa tttatagcat ttccatttac
    22921 taatttcgta gcagtttctt tttcagcttc tgtaatacaa tctccataga atatagcttt
    22981 taaatttatc tgtttatcat atctgctttt atgacgcatc atattatctt ttattacaaa
    23041 gtatggaaga atataattaa tgcttttatc aagtacgttt ttgacaaaag ggctaaaccc
    23101 tccgtaacag catctgctta ttataataat tccatcggat tcatttataa gtttacccat
    23161 gttgctgtaa taatctttta caacacattc agaaggagtt ttaatccagc aaccaaaacg
    23221 accaatacat ttgtggattt cttttgtgtt tggaagtatt tttatattgt catcaagctt
    23281 gggtaataac ttttctaatt ctttgtcagt taaatcatgt attaaaagct tcataaagtc
    23341 catctccttt tattatgtat gtttatttct aaaaattata tcttatagat ttttcagtaa
    23401 atctttacac caattaataa caaaattata atagtcaact ccataaatca ttgtggcata
    23461 catatatgta tattggtcaa tacaatgatt ttcttctaca tcaatttttt gtttacttaa
    23521 tttatttaga agtaattcta cttcagttat taacattttt aagtttgttt caattatttc
    23581 tttgggtaga tacttgtaaa agaatatatt aacaaggtgg tcttgctttg ttttagaaaa
    23641 atttataggt ttctttaacc attcgagaaa tacttcttta ccagtattag ttatggaata
    23701 tagttttttt aatttgctac catctataac ttcgtgatag tgtatatatc cttttgtttc
    23761 taatctttta agtgcaggat agatacttcc aaagctggcg tcaaaaaagt acgaggtact
    23821 ttctgacatt atttgtttta agtcgtatcc acttaattct ttttccatta aaaatcctaa
    23881 aataatgtat tctaacatat tacctcctgg tatcaatcag atatatatcg attcgatata
    23941 tttattatta cagataataa atattacgtc aagatgcttt ttaaaataag ctaaaaagaa
    24001 ttaggaatta ttgataaata tgcaaaaaaa ttaatataaa aggtaattaa atatcaatga
    24061 agatttaaaa atagttaaat taaagtaaga gtctaatata taaaatttat agtaacttta
    24121 tggtttaaat ataaacttgt gtgctattga caaagtataa aattagcagt aaaataattg
    24181 catgagcaaa tagattattg cgaacgcaaa aaaatgagga caatagatat taaaggagag
    24241 aatatgagag agctattaaa atgggtttcc attataaata gatacaatac aaattatatt
    24301 gacaggaaat tggcggatat tggaatcaat aatagccaat atttttatgt attacacata
    24361 tgtaataatc caggtattac acaggacact atatttgaga aaattcttgt gaatcctagt
    24421 aatataacga gagctttggc aaatttagaa aaagaaggct ttataacaag agaaccaggt
    24481 gtaaaggata aaagaacatg gcatttatat cctacagaaa aatctttaga atgttatgat
    24541 gaaatactaa aaataacaaa tgggtatgtt gaggagttgt tgagttcatt tgagaaagaa
    24601 gagcaagagt tgtttatgtc aatgttaaag aaagttgcat ttttagctat tgatatgaat
    24661 gaagaagcaa aattggaggc gaaggaaaat ggaagaaaaa tataaggagc cattggaata
    24721 tgaaaaggtt tcaaagttat taactaagta cgcaattcct agtattatag caatgttagt
    24781 aagtgcttta tataacattg ttgaccaaat atttattggg caaggtgttg gtgtattggg
    24841 taatgctgct acaaatgtca cttttccact aacaacaata tgtactgcaa ttgcattatt
    24901 attaggaatt ggaggagcgt ctaagtgttc attggaatta ggtgctaaaa attcagaaaa
    24961 agctacaaaa gcagcaggaa attctatatg cttgatggct gtttttggaa taagtttatt
    25021 tatagtagta tcaatatttt taacaccact attaaaattc tttggctcta catcagaaat
    25081 actaccttat gcacacacat atacaaaaat tacatcaatt ggattaccat ttcttataat
    25141 gtccactgga atgagtaaat tgatacttgc agatgggaga ccaaaagctt ctatgttttg
    25201 tatgttaata ggagcagtta ttaatacaat tttgaatcca ttattcattt ttgtttttaa
    25261 tatgggaatt gctgggtctg ctttagcaac tgttattggg caacttatat cttttggaat
    25321 aagtgttcat tatataaaga attttcaaca tattaaatta cataagaaaa gttttaaatt
    25381 agatagtata atttataaac atatatttgc gctaggttca agctcatgtt ttaatcaatt
    25441 agcaatgact gtaacacaga tagttatgaa taatacattg gcatattatg gggctaggtc
    25501 agtttatgga agtgagattc cacttgcttg tgtcggtatc attattaaag taaatatgat
    25561 ttttatatct ataattattg gtatatcaca aggtatgcaa ccaattatag ggtataatta
    25621 tggggctgaa aagtataatc gtgtaaaaga agcatataag tttgcagtgg gaagtgcaac
    25681 tattatatct gttattgcat tcttatgttt ccaattcttc ccaagacaaa ttacgtctat
    25741 atttggtaac ggaaatgaga cttattttat atttgcagaa cattatttta gaactttctt
    25801 gttcttaaca tttataaatg gtgttcaaat agtatcatca actttcttta catcaattgg
    25861 gaaatcagtg ttgggacttt ttacttcttt gactcgtcaa attttatttt taattccatt
    25921 gatagtaatt ttaccaatgt ttatgggaat tgatggagta atgtttgcag gaccaatagc
    25981 agatgcagca gcggcaatgg tatgtatata ctttgcagtt catgaaatga aatccttgac
    26041 tataaagcaa aataatttga tgagtaacca taataagatt gcagaggtat aagacaatat
    26101 ttaagaagta tagaaaatta atttaagaaa tataataaac taatttagga agtgtagaaa
    26161 attaatttaa agaagtataa taaactaatt taggaagtat agaaaattaa
//
LOCUS       DAEQJM010000053        25952 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.053, whole genome shotgun sequence.
ACCESSION   DAEQJM010000053 DAEQJM010000000
VERSION     DAEQJM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25952
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.053"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(50..391)
                     /locus_tag="KRQ43_002665"
     CDS             complement(50..391)
                     /locus_tag="KRQ43_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743011.1"
                     /translation="MLLILDNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRINKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(418..1089)
                     /locus_tag="KRQ43_002666"
     CDS             complement(418..1089)
                     /locus_tag="KRQ43_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743012.1"
                     /translation="MPILEILNLGKIYGKKETAVHALKDANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSSGTIKVDGKDICCLSDKKLAKYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKVDEEYIEDIINLLGLSERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            complement(1101..3686)
                     /locus_tag="KRQ43_002667"
     CDS             complement(1101..3686)
                     /locus_tag="KRQ43_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH2743013.1"
                     /translation="MKDNLKIALRYIISYKARSLAIALSIILATSLIVGIGTLSRSAQ
                     QAEVDKLKRETGSDHVYFKDINKNQLEYIKSRKDIKNLGITSHYGYTDPNERLAINLE
                     YANKNYLTNQSKLIKGHLPKASNEVVVEKWILNSLGLKPEINQNITFKLYQKEKPETF
                     KVVGILEDRPIEKNKGTCEIFLNLNESKLDKFSYAYIEFNNGIDINTSIDNIVKNTML
                     DENSVGKNKMLIESTRENGTLDNSSKYTAITMSLFSGIVIYSIYVISIYQRIQEYGIL
                     RAIGSTNFKIFKFMFYELFILALIAIPIGICTGIGGAQIFNRTAGNIQFEGNVTVTPF
                     VIPDKIILLSIGSIILTILIISFFTYLKIRRISPIDSIRKTFGTDKNINKVNSLISKL
                     TLNISVTKSISAKNIFRNKKGFIIIILSMSLGGIMIIKENYKYSFSDIQNKNGQEETY
                     MNADFILTNFFLKLNQSNKADSFKDIKGLNDNQIDKIKNINGIDKVKTASILDTRIEV
                     DKLNGLDYYNIINSTPYYKDFPLFIKNKNTGKYTMKQKLRGYNDEMINSLEKYLVSGS
                     INLERMKKENLAILYVPQVSKTNKYKLSYTPGTETPAVDIKVGDTIKVKYPKGEIDQD
                     LYIKLKDNYEYLEYEFKVGAIVSYPFADNYLYSGDQGIDVITSNDYLKKLTGVDKYNV
                     VYVDINKNANVKKINTLLGEIGSESPGTTTANMLMEKENFDKMTARALTYAYGIVAVM
                     FIISVFNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGILSSVITIVV
                     GLIIQFRMYYTYNFVSYGLGFSIDYKIYILVVLANIIVGILATYIPLRKINKISIVEA
                     INITE"
     gene            3894..4829
                     /locus_tag="KRQ43_002668"
     CDS             3894..4829
                     /locus_tag="KRQ43_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH2743014.1"
                     /translation="MENNFIFPIVILTLFIFSNLIMNKYRFYKELDILKRGILTFFVS
                     CFVWILFMEGIEYIQLSLGYNFLLEGVLNIILFLILIILSFYIGFKFIRLLDNNNKQE
                     YKLQKLDSKINHKDNIIVKLRSQKHDYLKHLQVVYSLLNTGLAEDAKEYITNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKNISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSAIQKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFLDGFSTKEGQDRGF
                     GLYLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            4848..5585
                     /locus_tag="KRQ43_002669"
     CDS             4848..5585
                     /locus_tag="KRQ43_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743015.1"
                     /translation="MIKVLICDDDKIVRDDIANIVKESGYVDYVKKVKDGIEAIEFIK
                     SEKIDLLIIDIDMPYKNGIDSAKEILSIDKDIHIVFVTGFADYSLESFKVHPIDFIVK
                     PFKKEKILDSINIAIDHINSHKIAKNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLYTRDEDTIKFYENFDDLKKRLPPNFFMTHRQYIVNLRLIHKVIPINKSSLEIKF
                     INFQESATLNKSLEKDFLYRFYRVKRF"
     gene            complement(5745..10802)
                     /locus_tag="KRQ43_002670"
     CDS             complement(5745..10802)
                     /locus_tag="KRQ43_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBH2743016.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVTSALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNSDRQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTSEDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKFKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGIDYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDESGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQLVQPFKQVFREYYRINSDEISEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNINFEGSHV
                     LITGNLGEYSVHMGSGIVHKKGMGALNILPVHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDNKIKDPSILSNL"
     gene            complement(10827..11246)
                     /locus_tag="KRQ43_002671"
     CDS             complement(10827..11246)
                     /locus_tag="KRQ43_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743017.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSPINLKSGDIFTFIRLTLLAGRMF"
     gene            complement(11479..11730)
                     /locus_tag="KRQ43_002672"
     CDS             complement(11479..11730)
                     /locus_tag="KRQ43_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743018.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGTKFINKKR"
     gene            11819..12550
                     /locus_tag="KRQ43_002673"
     CDS             11819..12550
                     /locus_tag="KRQ43_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBH2743019.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            12609..13520
                     /locus_tag="KRQ43_002674"
     CDS             12609..13520
                     /locus_tag="KRQ43_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2743020.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEVGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            13571..14383
                     /locus_tag="KRQ43_002675"
     CDS             13571..14383
                     /locus_tag="KRQ43_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBH2743021.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            14493..15185
                     /locus_tag="KRQ43_002676"
     CDS             14493..15185
                     /locus_tag="KRQ43_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH2743022.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            15272..16213
                     /locus_tag="KRQ43_002677"
     CDS             15272..16213
                     /locus_tag="KRQ43_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743023.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            16250..17407
                     /locus_tag="KRQ43_002678"
     CDS             16250..17407
                     /locus_tag="KRQ43_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH2743024.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRHFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            17559..18119
                     /locus_tag="KRQ43_002679"
     CDS             17559..18119
                     /locus_tag="KRQ43_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH2743025.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            18147..18638
                     /locus_tag="KRQ43_002680"
     CDS             18147..18638
                     /locus_tag="KRQ43_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743026.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            18867..19418
                     /locus_tag="KRQ43_002681"
     CDS             18867..19418
                     /locus_tag="KRQ43_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2743027.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            19504..20436
                     /locus_tag="KRQ43_002682"
     CDS             19504..20436
                     /locus_tag="KRQ43_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HBH2743028.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            20491..21354
                     /locus_tag="KRQ43_002683"
     CDS             20491..21354
                     /locus_tag="KRQ43_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH2743029.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFSNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            21601..23463
                     /locus_tag="KRQ43_002684"
     CDS             21601..23463
                     /locus_tag="KRQ43_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH2743030.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            23466..24932
                     /locus_tag="KRQ43_002685"
     CDS             23466..24932
                     /locus_tag="KRQ43_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH2743031.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIAKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            24956..25792
                     /locus_tag="KRQ43_002686"
     CDS             24956..25792
                     /locus_tag="KRQ43_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH2743032.1"
                     /translation="MNYIIKKVLNSSVVLVHDAKYNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKKFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
BASE COUNT         9558 a         3095 c         4048 g         9251 t
ORIGIN      
        1 ataataaatt tagaaaagaa aaaaattggg gcctattaag gcccccttac tattttttga
       61 tagatttatt taaaattact ttctcatttt gattttttat atttattata gagtcagtat
      121 aatccacttc aaagttggca aaagcagaga ataaatctat atctcttaac aaatgaattg
      181 tcatacattg attgttctta tttatcctta gaatcaatgc tcttacaaat ggaaattgta
      241 ttctagaatt aaataagtta gaaccatcag tatctatatc taagctacga taattaatat
      301 ctataaatat atctacatca tcattttctt ctcttattat tctgtagtca aaatctaagt
      361 ttaaatttaa attatctaaa atcaataaca tttaaatcct cttttctata aatagtttta
      421 gagtgttaat ttaagctctc catctattat agatataatt ctatctgctt ttctagcaat
      481 attttcatta tgtgttatta ttataagtgt ttggttatat ttttttatag aactttttag
      541 taaatccatg acttcttccg tagttttact atccaaattt cctgttggtt catctgctag
      601 gattatactt ggttttgcag ataaagcgcg tgcaatagca accctttgtt gttgaccacc
      661 agataattga tttggaagat gatttttcct ctcactaaga cccaataaat ttataatgtc
      721 ttcgatgtat tcttcatcaa cttttttatt gtctaacttt agtggtaatt ctatattttc
      781 ttttacattt aatactggaa ttaggttata ctgttgaaaa acaaagccta ctttttgtct
      841 tctatatttt gctaattttt tatctgaaag gcaacatata tctttaccat cgacttttat
      901 agttccacta cttggtctct caagacctcc tactaaatgt agaaatgtgc tttttccact
      961 tccacttggg ccaattatcg caacaaattc acccttattt atttttaaat ttgcatcctt
     1021 tagtgcatgt acagctgttt ccttttttcc ataaatctta cctaagttaa gaatctctaa
     1081 tataggcata attaatcctc ctattctgta atgtttatag cttcaactat actaatttta
     1141 tttattttcc ttaatggaat atatgtagct agaataccta caattatgtt tgctaaaaca
     1201 actaggatat atattttgta atctattgaa aatcccaatc catatgatac aaaattatac
     1261 gtgtaataca ttctaaactg tattataagc cctaccacaa tggtaattac acttgagagt
     1321 attccatata atattccctc atagagtatc atatttttaa atcctctctc agagatacca
     1381 atagctctta acattccaaa ttcgctagtt cttgaagtta agttataact tatgttattt
     1441 attatattaa acacactaat tataaacatt actgctacta ttccataagc ataagtcaga
     1501 gccctagctg tcatcttatc aaagttttct ttttccatta gcatattagc tgttgtagtt
     1561 ccaggagatt cacttcctat ttcacctaag agtgtattta tcttttttac atttgcattt
     1621 ttattaatat ctacataaac tacattatat ttatctacac cagttagttt ttttagatag
     1681 tcgttacttg ttattacatc tataccctga tctccagaat ataggtaatt atctgcaaaa
     1741 ggataactta caatagctcc aactttaaac tcatattcta gatattcata attatctttt
     1801 agttttatat aaagatcttg atctatctca ccttttggat atttgacctt tatagtatct
     1861 cctactttta tatctacagc aggcgtttct gtaccaggag tataacttag cttgtattta
     1921 tttgttttag aaacttgtgg tacgtataat atagcgaggt tttctttttt cattctttcc
     1981 agatttatac tcccactcac taagtatttt tctaatgaat ttatcatctc atcattgtaa
     2041 cctcttaact tttgtttcat tgtatatttt ccagtattct tattttttat gaatagagga
     2101 aaatccttat aataaggcgt tgaattaata atattgtagt aatctaatcc atttaattta
     2161 tctacttcta ttcttgtatc taagatgctg gcagttttga ctttgtcaat tccatttata
     2221 ttttttattt tatctatctg attatcatta agtcctttta tatccttgaa agaatcagct
     2281 ttattagatt gatttagttt taagaaaaaa tttgttagaa taaaatctgc attcatatat
     2341 gtttcttctt gaccattttt attttgtata tctgaaaaag aatatttata attctccttt
     2401 atgatcatta tacctcctag actcatggat aatataatta taatgaagcc ctttttattc
     2461 ctaaagatat ttttagcaga tatagatttt gttactgata tatttaaagt taattttgat
     2521 atcaaagaat tgaccttatt tatattttta tcagttccaa aggtttttct tatagagtca
     2581 ataggagaaa ttcttcttat ctttaaatat gtaaagaaac ttataattag tattgtcagt
     2641 attatacttc caattgataa aagtattatt ttatctggaa taacaaaagg ggtaactgtt
     2701 acattacctt caaattgaat atttcctgca gtcctattaa atatttgtgc accaccaata
     2761 cctgtgcata taccgatagg tattgctatc aaagcaagta tgaaaagttc ataaaacata
     2821 aacttgaaaa tcttgaagtt agtggatcca atagctctta agataccata ttcctgtatt
     2881 ctttgatata tcgatataac atagatacta tatattacaa taccagaaaa taggctcata
     2941 gtaattgcag tgtatttact tgagttatct aaagtaccat tttccctagt agattctata
     3001 agcattttgt tttttccaac actattctca tccaacatag tattttttac tatattatct
     3061 atgcttgtat ttatatcaat gccattatta aattcaatat aagcataaga aaatttatcc
     3121 aattttgatt cattgagatt taaaaaaatt tcacatgtcc ctttattttt ctcaataggt
     3181 ctatcttcaa gtattcctac aactttaaat gtctctggtt tttctttttg atataattta
     3241 aaagtaatgt tctgatttat ttctggtttt aaacccagac tatttaaaat ccatttctct
     3301 acgaccacct cattactagc ttttggaagg tgacctttta taagtttgga ttgattagtc
     3361 aagtaatttt tatttgcata ttctaggttt atagctaatc tttcattagg atctgtatag
     3421 ccatagtgag atgttatacc taaattttta atatcttttc tagactttat gtattctaat
     3481 tgatttttat ttatatcttt aaagtataca tgatcacttc cagtttctct ttttaattta
     3541 tctacctctg cttgttgagc acttcttgag agggtaccaa taccaacaat aagtgatgta
     3601 gcaagaatta tacttagagc aattgctaaa gaccttgctt tataacttat tatgtatctt
     3661 agtgctattt ttaaattatc tttcatattt accacttcct ttcttagcta aatcaattat
     3721 atgtttattt aaaatatata tcaaagtaag tatcttcaag ttttgagtac ttaattgtac
     3781 aaatttatat gtgtatttgc aagtttaatt aatgtacatg taaattttga ctttttacat
     3841 aatttttcta aaatgatata atcctcatat aaagtgtaga tgggagggga attatggaga
     3901 ataattttat atttcctata gtaatactaa ctttgtttat atttagtaat cttataatga
     3961 ataaatacag gttttataaa gaattagaca tattaaaaag aggaatatta acgttttttg
     4021 tatcgtgttt tgtatggatt ttattcatgg agggtattga gtatatacaa ttaagtttag
     4081 gatataattt tttacttgaa ggagtattaa atattatact ttttttaatt ttaattattt
     4141 taagctttta tataggattt aaatttataa gattactaga caataacaat aaacaagagt
     4201 ataagctaca aaaattagac agtaaaataa atcataagga caatataatc gtaaaattaa
     4261 gaagtcaaaa acatgactat ttaaaacatt tacaagtagt atattctcta ttaaatactg
     4321 ggttagctga agatgcaaaa gaatatataa cgaatatatc aaatagcttt aaatcaaaaa
     4381 attcaagata tgggaaagta tcttatttag atgctatagc ttccttaaaa tatgaggaat
     4441 gtcttgaaaa gaacatatct tttgatgtat atatccaaga ttttatggat aatttagaga
     4501 ttgaacctaa tgatatgagt tcagtgctat taaacataat agacaatgca atagaatctt
     4561 tgtctgctat acaaaaggaa aagaagtata taagattaca tgcatatgaa gatgaatttc
     4621 agtatattat agccataaaa aataatggtc ctaaaataca taatgtcgaa agtatatttt
     4681 tggatggatt tagcactaaa gaagggcaag acagaggttt tgggttatat ctagttaaaa
     4741 atatactaga taagtatgat tatagtatac ttgtaaatag tgacgatttt ttaactgaat
     4801 ttgtaatttt aataccaaaa tattattagt taggaggaga gaagtctgtg ataaaagttt
     4861 tgatttgtga tgatgataaa attgtaagag atgatatagc aaatatagtt aaagagtccg
     4921 gatatgtaga ttatgttaag aaagtcaagg atggtataga agcaattgaa tttataaaaa
     4981 gtgagaaaat agacttattg attattgaca ttgatatgcc atataaaaat gggattgatt
     5041 ctgccaaaga aattctttct atagataaag atatacatat agtttttgta acaggttttg
     5101 ctgactatag tcttgagagc tttaaagtac atcctataga ttttatagtt aagccgttta
     5161 aaaaagaaaa aatacttgat tcaattaata tagcaataga ccacattaac tctcataaaa
     5221 ttgcaaaaaa taattttata gaagatactc tttttgtata taaaataagg aaacagatac
     5281 atatgattaa ttttgatgat atagtcatgt ttgagaaaaa ttcaagagct attaatttat
     5341 atactagaga tgaagatacg ataaaatttt atgagaactt tgatgattta aaaaaacgcc
     5401 tacctcctaa tttctttatg actcatagac aatacatagt aaatttaaga cttatacata
     5461 aggttatacc tataaataag tcttctttag agataaaatt tataaatttt caagaaagtg
     5521 ctactttaaa taaatcttta gaaaaagatt ttctatacag attttatagg gttaaaaggt
     5581 tttaatgaag aaaaaaattt tcagtgatat acaatatgta tgatgaagat atcatataaa
     5641 tttgctatag ttataaatta attcgtataa aatataatat aaaacatatt ggactttcat
     5701 ggaaaattag aaagcccaat atgttttaga gataaatctt atatttataa gttgcttaag
     5761 atactagggt ctttaatctt attatcttca gcaagtaata agattttaga cataatctca
     5821 gcagtcttag ggtcttcatc agcgaatgga aggaatatct tacctctact ttgagaatgt
     5881 acaggaagta tattcaaagc acccatccct tttttatgta caataccaga acccatatgc
     5941 acagaatact cacctaaatt acctgtgata agaacatgag agccttcaaa attgatattg
     6001 ttaattttta ataataataa aagttcttta gcaattgcta tacgcatctc tacagtagaa
     6061 tggctagttt cagggtcaac accaccagca tgagcgacac ttacaacaag gtctatatca
     6121 cgcataactt ctgagaatag aattggaggt atagaagcta attctaaact tttataagtt
     6181 tttctatcaa aaaattctac tgtttcaata gtaggaggct ctatatctgc tggtgaaaac
     6241 caatctgcaa gtgcaaacat ctttgccact atattttctt tataaaatac tttctgtaat
     6301 ccctcttcat aatcgacagt ccaaagctga tttctaagaa gtgctacagt tttctttggc
     6361 tgaatttggt gaccagcata tctgcgagat atagtttttt cagatatttc atcagaattt
     6421 attctataat actcacggaa tacttgctta aatggttgaa caagttgctt actaaataaa
     6481 tcatgttgga actcactcca cttaccagat tcaaacaaat gaactggatg tgcaagtttt
     6541 aatttatttt ttgctgtcaa cttataagtt tcaccttcta tattgcaaat aaagaactta
     6601 gacttatcat tataaacata tccaatatta tcatcacata cccatactag atttttaatc
     6661 aaagggcaga taactggatt tttatagata ttggcaattt ctttaactgt aaatactatt
     6721 tcatttttca tagcttgttc taaactctgt tttgcacgag aatactgact ctttaaatct
     6781 ttttggacag atttaagttc aagtacatat ggatgtttag caatagcttt tggtatactc
     6841 tttaaagact tgttgccttt ttgaacttta gtagatgctt ttccgctttc atcaacatct
     6901 atccaaattg aagtaccatc aatatctttt ggtttaaata gatgagcaac ttcatttagt
     6961 ttttcagtct caagagccca catcatacga tttacatctc caaatccagc acttctagct
     7021 agattttcta gcgctatagt acaagctttt gattcacttt cacgacgttg tgcaccaaat
     7081 tgcttgcttt ctttagcaaa cttttgaata aattcataac ggaaagttgc ttcttttagg
     7141 tctccttttt tcataggaag taaagagaaa cttctcaatt tatcttgatt tctatttgtt
     7201 tcaatttctt tcatcaacat gtctttatca agcttaccaa gtgtagcatc agcatagagt
     7261 tgtgcacgtc tatgagagtt accaccacta gttatatatt tagctgactt gtaaagtata
     7321 ttgaatcttt cttccccaat agttttatat gaatctaaga accaatctac atcaaatgca
     7381 ccatcaatga aactacgtgg tgaaataggg gagaatagag caacctctga ttctttttgt
     7441 gcagagaagc cttcatttat atgtgcatgg aagtaccaaa ttgtactttt cagacccttc
     7501 cagtttaaat atttttcaat tatgtttacc cattgagggg catacatagc agattctatt
     7561 aatcttaact cagtaatgtc ggtattttta agtaaacttt ttaatttttt tgaatcatct
     7621 tctttagtag gatagcaatt tttaagtaga gaacttaaaa catctttttt tgaataattg
     7681 ctaccatatg aatatcctct ctggaaagtt tctttaccaa gagcgaccaa aatatttaca
     7741 aaataatcta taccttcaaa gtattgtata ttattagcta gatgagacac ttctgttggc
     7801 atatcacctc tacgtgattc aatttctata attcggtttg taacagtttt taaattatct
     7861 ttaagccaag ggtacttttc taatgtgtca ccagcccatc taggatttgt taatgttctt
     7921 attatatttg atgcgttgta tccacttatc atttctctat taacttgctc ttcagtcatt
     7981 aaacctaatt catgtgcacg agcaaacaca tttatgctag tatagaaagg aaacttatat
     8041 tctagcaact gataatttga aaacgtagtg tagaaaaact tagtaaaaga aatatcatca
     8101 taaataaacg aatgtgcttt atcaagccaa tagtttaaaa taggggcatt taaagcaggg
     8161 cagtattcat tttgtctgta atagttttta gtaaattcaa ctctttgttt tttacattgt
     8221 tctatagtca ataagtttct aagtttatag tatatttcta aacaatagtt aaatatttct
     8281 ttatggtcaa actcatttag taaaactctt aaaagttttc ttgtaagtcc attaaattta
     8341 aatttttcaa gttttgtata tattttattt tgttttttag agtcaaggac atttgaatat
     8401 atagatgaaa accaactttt ttctgtttca ttatatccac atgtacttat actataaaat
     8461 aagatatcaa gtattaattt gtaatctaag tcaagctttt tactagtttc tctccaaagt
     8521 tctgccaatg gataattatc aagagtatca ttagaaactt tatatttaat aggagtcaag
     8581 ttataagtag aataacctaa aagcactttg tctacattac ctgaccatct ttcaacttca
     8641 tattcataat ctgcattttc agtaataagc tcatcaaatt tttcataaac ttttattatt
     8701 ttatttatat ccgtatcgag aatttttttt gcttcttttt ttgttgctac agaaacagaa
     8761 tcctcactag tagataaact tatatttgaa ataattttat taagctttga tgagctatta
     8821 gaatcatctt taaaatcaaa ttgttctgga atttgaactt tgttttcagg gttatatatt
     8881 ccaaaaccat tttctttgca gtaatcattt tttgctttac ctaacaaatt atcaattaat
     8941 atttgaactt gagatgtatt ctttttagat ttatcaatat cctctataag taaaataagc
     9001 ttattatata gttcttgtct atcagaattg tcttttaata agtttacaat ttcaagacct
     9061 ccaaggcatt tttgagaatt tgaagatttt atcagtgaag aagcaatatt ttccaaattt
     9121 gaatcatctt gttcaagtaa aatttttatt actgtttgtc taatagagct tgtctttaaa
     9181 gacaatagat tggttatctt atctaattct acatctgtta gctcaagctt tctaagtaaa
     9241 ctcaataccg tttctctatt ggaaacactc ttatcactta aacattccaa taaaaattca
     9301 cgttgtctat ctgtctttgg ttcatttaca aaattgacta taagtgaagc tcttaaatct
     9361 gaactcataa gatgacaatt ttccataagc acatctataa attgagcatt catatcgtat
     9421 gctgttaaag tcatcataca tttaagtatt tcatgagaag aaatttcaat ccaagtccat
     9481 ggaaatacac ttcctgaaaa tgattttgtc tttgaattta aaatttctaa agtatgtttt
     9541 aaactttcaa attgttcttt tctagcatca aagtctttgt caataggagt gtttgacaag
     9601 tcaaaattag tttctctgtt ttgccaacta tagtagtagc caacagaacc ttctacatag
     9661 aaatttgtaa ttacccatgc tagtatctct aaatcatcac ccttaatgtt tttagatgct
     9721 atagaatgtt taaaatatgt actttctgta tgcgataaaa agtaaagagc tacaagtttt
     9781 ttatattttt cctgacaaga aagtaagttt tcaataagag agtaagagtc atatatgttg
     9841 taagttgcag tagcccataa ggcaaaataa atttcaagat tatcattgct attaattgat
     9901 tctatacgga acttttcatc agtcaatgat ttatatgaaa gttctaaaca tttacgtatt
     9961 attccaggtt tttggtctga aaaaccaagt cctgtccatg tatccaaggc tcttataaca
    10021 gaactaaatc gctctaaatt gttgtccaaa atagttttta acatgtatat tgatgcagaa
    10081 attgtaccct catctaaact ctctacaatt tgctgtctaa gtccttcttg ttgtttggct
    10141 gccaaaagaa gtttagaaag catttcatag catttatcac tatgactctt catgatacca
    10201 attatcattt gtcttgtaag tagagcagtt tgattttctc caaatattac ttcttctaag
    10261 gcacttgtta ctttttgatt tcctttgtct atttctagtg ctattttatc actcattata
    10321 gagtcatagt acaagacctt atttggaaga gtaagataat ctataactga aaaatcataa
    10381 taaattaaat caacatagtt tgaaataaac cttataatac ctctaaaata atccacaagt
    10441 ttatttgagc gatacccttt acgataatat cctcctgaat atgtataatc catctttctt
    10501 ttaattaatt ggcaaagttc ttctacttgt tcagaagtaa atattaattc taatgcattt
    10561 tttaaaggtc cagaaaggag ctcgtccata tttttaattt cgtagtagtg gcaattgtag
    10621 tatttcttta tcatatttaa gaatttgtcc tcaggttctc tataatagta tgaactattt
    10681 tctatgcagt cccaaagaga ttttgctaag tcgtagtact gttttgaaga agatttagta
    10741 aaattatttt taaaattttc aattatttta ggattttttt ctactctagt acgttctaac
    10801 atttatgtac ctccaaatta tttattttaa aacattcttc cagcaagcaa ggtaagtctt
    10861 ataaaagtaa atatatctcc acttttcaga tttatagggg aatcgagttt ttcaataaca
    10921 tcttcattta taagcacttt gtagattcca tcttcaaatg cctgtaacgc tacttctatt
    10981 gccttttcta cagattgttt attctcattg taaatagagc caaatccaac ttttccaata
    11041 tcagcttgag attcaatttc ttcattagtt aagaagttta ttattgattt ttctgggatt
    11101 ttctcattat attcaagaac atttttagat acaatttcag agatagcttc ttttaggcaa
    11161 ttgatgttgt cagatacatc aaaaggggta agttctaaca taggtttgcg tttgccaaca
    11221 gccttaactc taaaataaat ttgcataaaa tcacctcgca aaatattaat tatgtattta
    11281 gaaatttaaa atttatctat ttgttatatt atatcatttt gtgaattatt aatgtgaatt
    11341 atggaattat tttacaaaaa atagaaaaaa agctatctta aagtctaaaa aagcaataaa
    11401 agataacttt taactataat tatatagaat tataactgta catttattaa attttaattt
    11461 tagaattatt tttgataact atcttttttt atttataaat tttgttccta aatatttttt
    11521 gatatcttct tcaggagaaa agtcatcaat aagtatttct ttcccagtgt cttcaaatac
    11581 tacaagaact tcacagtcac cttgcaagaa aaattttcta actgtatctt ctttaacttc
    11641 tctaactttt attacattct ttttttcttt ttcaaagtct tttgtgtaat aacttcccat
    11701 catattaatt atttttgtat atctattcat aaaatacctc catatgcgat taaatttaaa
    11761 aaatatgtta taataattgt ttgtattaac ttaataatta taacaaggag taataataat
    11821 gactagtata aaaaataaag atattttaaa ttgtatagat tattccatta aaaataagct
    11881 ctttgacaaa ctaaatgatg tatataagtc cttgccagta ggaaattgtt ctggatgtgg
    11941 aaattgttgt atggagtcag taggtataaa tttaattgag tttttgaata tattttgtta
    12001 tcttgaagat agagttgatt taaaaaaaag ctgtataagt aaaatattag attattattt
    12061 tgaggagtat acaagaaaga acccatgtcc atttaaagat actaataata gatgtctaat
    12121 atatgaagtt agaccattaa attgtaggat gtttggacat tggaaaaaag aggattataa
    12181 taaaaattta gataatgtta ttgagaaaaa taataactat agagagttaa tgaaaaagca
    12241 atatggattt gaaataaatg atgaagtagt aaattacagg atagattatt gtgatagatt
    12301 tattccaaat aaagattatt taagtaaatc taagagatta agcttttttg atgagcttat
    12361 gatattagac tcaaatattt attcaagtgg aaatatagat atagacttta gggatagagg
    12421 tatagttgaa tattttatag agtcattact ttatagaaat ttagcatata atgtgaaaat
    12481 aaggatatct aaagaataca aaataagaaa aagaactata gatagaataa aaagaattgt
    12541 tcttgtatag ttttatatta gtaagtaata aattgtatca taaatattgt caaaatgagg
    12601 tgaggaaggt gaatcttaca aaagtaaaag gaaatacctt ttttataaaa ggtggcacga
    12661 atacaggaat atatgtattt gaagataaca cagcacttat gatagaccca gggttatgtg
    12721 gttcaagacc taggagagta aataaagtat tagatgaaaa taatatacag gttagatata
    12781 ttataaatac tcatggtcat gatgaccact atggagcttg taatcaattt aaagaatatt
    12841 ataaagatgt gtgtataatg tcatctgaat acgacaaatt atatatagaa aatccagaat
    12901 tgttttcaaa gtatattgtt gggggaaaga gcaatgtatt tatggataat atcttaaaaa
    12961 ataaaatgtt ggatgatata aagatagata aatctataga agttggaaaa attgaattaa
    13021 acaatgaaat gtttgatata attgagtttc agggtcatac acctggtagt atagctgttt
    13081 tgacgaagga taatgtgatt tttgttggcg atttattgat aggagatgaa attctatcaa
    13141 aatacgattt cttgtttcta tatgatatac aagaacaaat aaattcatta gaaaaattaa
    13201 aaaatataga ttttgagtac ttagttttag ggcatggcaa gcaagttata tcgaaagaag
    13261 attcttataa attaatagaa aaacatttga atgctttaaa aaaatattta tatcaaataa
    13321 gagagttgct tgtagaaccg aaatctttag aaattttatt aaaaaacatt ataaataaca
    13381 ataatttaag caataattat aaagagtatc atttttttaa atcttcgtta gtatctgtca
    13441 taagttactt agttgattta gaagaaatag ggtatatatt ggaaaatgga gaattgcttt
    13501 actatacaaa aacaaaataa attatgataa aataaagaag gtcataaaaa acaaataaag
    13561 ggtgagcaat atggaatacg aaaaatggaa tgagatacta gcaccttatg aacatgcagt
    13621 agaggaattg aaaataaaat ttaaaaatat aagaaaagaa tatttagcaa aaggtgaata
    13681 ttctcccata gagtttgtca caggcagaac aaaaaaaata tcttccataa tatctaagtt
    13741 aaaaaggata aatgcaaaag atatagaaac tgaaattgat gatattgctg gtataagaat
    13801 aatgtgccag tttgttgagg atatatatgc tatagttgat ttgataaaag taagaaatga
    13861 tatgactata ataggagaaa aagattatat tacaaattac aaagatagtg gttatagaag
    13921 ctatcatgtt ataataaaat accctataaa ctccattgcg ggttcaaagg aaattatatg
    13981 tgaaatacaa ataagaactc ttgcaatgaa tttctgggct acaatagaac attcattaaa
    14041 atataaatat gaccattaca tacctgagac tcttgctgaa aggcttagaa gagcatctga
    14101 tgctgccttt cttttagacc aagaaatgag tgaaataaga gaggacataa tgaaagctca
    14161 ggctatgtac caaatgaagt ctatagctat tagagatact ctaaatagaa tacaagagtt
    14221 atatgacttg ggtgatacac ataaagctat gcagtaccaa agaaaacttg atagaactga
    14281 aacagataaa aatataactg aaattttgga attaaaacaa gaaatagata tattactaga
    14341 gcaatataag gatactaagg tagatgataa agtagttcag taaaaaacta cttgtagaaa
    14401 atttgctaaa tattaatggg gctgcctctt aatggaaaat aatttctaaa aagagacagc
    14461 ctatttagtg taattaagaa aggaatgata ttatgagttt gtatgctata ggtgatttac
    14521 atttttcaac atcagtcaat aagccaatga atatctttgg aagtaattgg gatggtcatg
    14581 aaaagaaaat tatagataat tggaaagaag ttgttaagga agaagatatg gtcttagtac
    14641 taggagatac atcttgggga attaatttat cggaagctaa aaaagattta gatataataa
    14701 gcaaacttcc aggtcagaaa atacttataa aaggaaatca tgattactgg tggacaaccg
    14761 ttacaagttt aaataagcta tatgaagaca tgcgttttat tcagacaaat ttttatgaat
    14821 ataaagatta tgcaatttgt ggaggtaggg gctggatatg tcctaatgat gttaaatttg
    14881 atgagactga tgaaaaagtt tataaaagag aagagcatag acttagacta tcattagaat
    14941 ctgctcgtaa aagtggtcac tcaaaaataa ttgtgattac tcattatcct cctacgaatg
    15001 ataaattgga agaatcttta tttacaaagt tatttgaaga atataatgtt gaaaaggtga
    15061 tttatggtca cttgcatggt aaagaatctt ttaaaatggg attgaagggg attcgaaatg
    15121 gagtagaata tacattagca tcttgtgact atacagaatt taatttaata aaagttcacg
    15181 attaaaaaac ataaattggt aaatactata agatacatga ttaaaaataa atatttgagg
    15241 gatttcggtt ttgagaaagg agacacgact tatgaggtgg atattagttt ttatattttt
    15301 atatcttatt cctttagtag tgatattcag aaattacaag aattttaaga ggtcttgtat
    15361 ctacagtagt atttatgtgg tattagctac aacaataatg ataagtaata tttatatgag
    15421 tggacttaat aaaataaaag agtctatgta ttatcacaat tatatttctg atgagacata
    15481 tgatgaaaag tatgtatcaa attttaagga aaaagaaagt accgatttaa aacaggataa
    15541 taaaaagaat gaagaaatat caaataataa aaatttaaac aacaaacaag atagaaatat
    15601 acaaaataaa gaaagtaatg aagaaggaag taatgatata aaagaaaaga ataattctga
    15661 tagtaatgtt tcagtgaata ataaatcaga aaaacaagaa gataatacaa aagaaaataa
    15721 taaatataca agtaaagaaa aaaatagtga agatataaaa aaaatagata tggaaagtat
    15781 aggaattttt aagaaagaaa tttataatat agaaagagca gctttagttc caatgagaga
    15841 atgtatacct tacactaagg atatagcaaa aaatataact aaattatcta gtataaaaaa
    15901 agatgttaca aatgccagaa acaagtgtaa agaagttgta aaagaatatg aaaatatgca
    15961 gattccagaa ctttctaagg agaagtatac agaaacattg agtaatgcta gagatgacgt
    16021 aaagaaagca tatgagctta gagaaaaatc tatggaaagt gctttgaaat taataaatac
    16081 taaaagccct aaatatatag ggaagataac agaatatctt gatttatcag ataagcagat
    16141 agaaagtttt aaaaatagat tgaacgattt aaaagaagaa ataaataatt cagaaacaaa
    16201 taatattaat taataagatt taaagatata agttaaaagg gagattatga tgaataaaca
    16261 gagtatagga aaactaaata tgttttttat ggggattact caaagaaacc ttgataatag
    16321 gcattttttt attgagttag aggtgatttt taaatctgga agaaaagagt ttaaaggaat
    16381 tgcaatagag gaagataata aatataaatt taattttaaa ggaaaatcag atttatatac
    16441 gtttaatgag ttgcttaaga atatttctaa agaggcagaa aattatgatg gattagtatt
    16501 taaatatgtt gagcgaggaa ctattgttgt aattgaagga gacaataaga aggtaaatgt
    16561 aaaatattta gataataaag aagaagtacc taaaatagat gaatttacgg catctcaaat
    16621 aaaaaacaga gattattatg taaaagtagg acaagcaaat gcacttttaa aagaaattgg
    16681 agtacttaca aaagatggta agataaaaaa tgataaaata agaaaataca atcagataga
    16741 ccattttgtt gaattgatag atagtatttt aaaagaaata aaggataaag actgtataac
    16801 tatcttggat tgtgcttgtg gaaaatctta cttaagcttt gtcttaaatt tttatataaa
    16861 agaagtattg aagaaaaact gttattttat aggaatagat tattcagatg tagttataga
    16921 agcatcaaaa aatatggcta aaaacttggg ttataaaaat atgtcattta taaaagagga
    16981 tttgactaat tatacaccta atagggatgt tgaccttgta ataagtctac atgcttgtga
    17041 tacagctaca gatatggcaa taggtctagg aattagagca aaatctgaag ctatagtagt
    17101 agtaccatgt tgtcataagg agttattagg gcaatataga tatgaagcta tggaaccaat
    17161 attaaaacat ggtgtattta aagctagatt tgcagatttg ataactgatg gtttaagaac
    17221 attgttattg gagggcaatg gatatgatac ttctgtagta gaatacatat ctccacttga
    17281 tacaccaaaa aatttaatga taagagcgat aaaaactaaa acgaataatg acaaagcatt
    17341 aaaagaatat aaagaactga aatcacaatt tggagtggaa ccaaccttag aaaaacttat
    17401 atattagtta aaaatgtaaa atttacgaaa agcttgctta aatatgcaag ctttttggta
    17461 ttatataggt atagtcatat ccagagtttt gatttataat taaagctgtg ctataatatt
    17521 tgattaatca aatcaataaa tgttacatgg aggtaaaaat gaacaaattg aatatatgta
    17581 ttgatataga tggaacaata acaagccctt atcattttct tccataccta aatgatatct
    17641 ttaataaaaa tataactgaa gcagagtgta taacacataa ttgggaagaa ttgtatggtt
    17701 cgggaataag agatgtgtat gcggagttta ataataagta tatacactca tatgatgaag
    17761 caaagattgt agagggtgct acagaggtaa ttagcacatt atctaaagga cataatttat
    17821 cttttgtaac ggctagacat gagtgtttaa ctgatgtaac taaaaattgg ctatcgagac
    17881 aaggattttc agatatagat gtttacttat taggaagtga ttataaagtt gaaaaggcaa
    17941 gagaactgag ttgtgacata tttatagaag ataatccttt aaactcagtg caactagctg
    18001 atgatggtgt taaagtaata cttctggata ctaactataa taaagatgtt aaacatcaaa
    18061 atatagttag agttagtaat tggatagata ttgaaaagat tataaaacaa ggtatttaaa
    18121 gatttgtaga ttgaaagggg gagcatatga tagatttaaa aattgaaaat agaaaaggaa
    18181 aaatccatgt aaagagcagt gaaataaaag acattttaga attacgtcca gacttcgaat
    18241 atgtacaaga tatatcaaat actataaatc aagaaaatat attggtattt gattgccagt
    18301 tgacaggaaa ttcttttgat atggatgatt tagatataga agaaatattg gaagagttag
    18361 gtgaagaaat agatgagtct tatttcagtg ttttatttga agatgtaaga gcgtatttaa
    18421 aagatgctac tgatgagata gaagcagact tacaagataa ttacttattt gataatttga
    18481 gatgttattt tgatatatac aatataaatc aagaatttac agattttaag tttgtatttt
    18541 tagtttcttt taaagatata aaaatttctt cattagcaaa cctagctaag attgtttcta
    18601 agagacagct tataggtgca tctaagtttt atagttaaaa tgaaatatta ttataataaa
    18661 agctagtagc cttgtaaaaa tataggttac tagtttttta tttgttcact ttcacaaaat
    18721 ttcagaaaac tatttacatt ctaaaaaaag taatgtatat taaacataat gtacagtata
    18781 atggataaaa agtttctatt aaattactaa gtttatttaa taatcaaaat aatttatctt
    18841 atattagtat gtattagggg gtatttatgc aaagtttaaa tgaaataatc gctgaaaatt
    18901 taaaaaagat aaggaaagaa aaacatctta gtttagacaa gattgcacaa cttagtggtg
    18961 taagtaagag tatgctatct caaattgaaa agtgtgaggt aaatcctact atatctactt
    19021 tgaagaaaat aactaatgga ctaaaaatct catttacatc attgatggag aggcaggaaa
    19081 gtgacataga attgattcaa aaaagtgata tagaccattt tattgaagat aatggaaagt
    19141 atataagtta tccaatattt ccatttgact ccaaaagaag atttgagata tttatgattg
    19201 aaatagaaga aggtggaaat ttagattcaa atgctgaact tccaggaaca caagagttta
    19261 taactgtttt tagtggcgaa gtaaccatta aaataaatgg agaagattac attgtatcta
    19321 gtggaaattc tataagattt aaagctgatg tatcacatat atatagaaac tcaggcaaag
    19381 gtatagctaa aatgagtatg gtagtatatt atatataaat aatttaatgg aattagagtg
    19441 atatttagat gattttaggt atgaagatat attatattta agttatagga gtgtgattta
    19501 tggatgaata ataaaaaagc agtttttttc ttttgtagtg atttaaagaa agacccagta
    19561 gccagtaatg tgataaagtg ttgtgaagaa ataatggatt taaatcaaac tgatattgtt
    19621 attgatgata attttgtatt agaatttaag gataaaaaca ataacttatt tcattttgta
    19681 aaaacaaaag atgtaataag tcataattat aaatattatc ttccaatttt aaatagacat
    19741 ttcagagatt atgattttgc aggagttgta aattggcatg agggagaaaa tgctccagaa
    19801 catatcctaa cagctcatac aattggagat gttccaacag gagaatttgg aaattcaaat
    19861 ccaagatact ttaaaaatct aatcaatgct attgaggata taaaaaatga aaatctactt
    19921 gatgaattta ctacattaac agaagcaact cactggtctg gaacaacata tggtgaagaa
    19981 tctaaattaa ttacagaata ttctgtacct atgttggata ttgagatagg aagtagtagt
    20041 gatagtttta ataatagtat agcaatacag gtattggcaa aatcattaat tagagtattt
    20101 gattgtgatg aacctttgaa gactttatta tgtgttggag gggtacattt tgagaaatct
    20161 ttctcagata ttataaaaaa taaagaatat aacatatcaa ttggacatgt attgccaaat
    20221 caatggattg taagtggaat gtatgatgat gaatcgggat ttgagaaact agaaaagtgt
    20281 ataaatagta ttgaaggtgg aattgattgt atagtttttc atgataaatt aaaaggtacc
    20341 tataaagagc aatgccgtaa actaggtgaa aaacttaatg tacctgtatt taaacataaa
    20401 atattaaaaa atcccaaaga cttacctata tggtagtctt atacagttaa tataacaata
    20461 agtcggatta atttttaagc gaggtcaaaa atgatattat cttattttgc attattaatt
    20521 agagtagtgc tattagcttt tgaaagagta gttgtaagat tattaggtga tgaagaagga
    20581 gatatttata aaaatatagc ttcatcattt ctatttttct ttataggggg agtatgttta
    20641 cttccattta gcataatgga tagagttagt gattggtcgt ttttaatacc atgttatata
    20701 agtagtttag tctattcaat tggttcagta gcgtatgtaa cgtctttagc aactggggaa
    20761 gtttcacttg ttactccaat aaatagttta aattcattgt ttttactgct tttatcagtt
    20821 atatttttag gtgaaggttt aagtttagca aaagttgcag gaatcataat tatgattggt
    20881 ggagtgttta tattaaaaaa agtaagctct tttttaaaga atgtctctgt aatttttaac
    20941 aatttaccat gtagattaat gtttttatac atatttttgc agtcagtagg aagagtattg
    21001 gataaggctt tttttgtaca agtatctcct atattatatt caactatact gtattttttc
    21061 gtaggtttaa atttatttat ctttttagca tttaaaaaga aacaaaaaat aatttgtgag
    21121 atttttagta ataaaaaggg gctttcaatt ttaagtggtg ctattaatgg atattcttat
    21181 ttagcattat taattgcttt aaataatcta gaacttagta tagcagagcc attttctcaa
    21241 gtatctatga taataacttt aatacttgct cattttatat tcaaagaaaa tataaaagaa
    21301 aaaataccag gttcaatttt gatactaatt ggtgggtggc tactgttact ttaattgaca
    21361 taaaaaatga attataaagg tgctattagt tagtatcaga aaatttaaaa aagtattgac
    21421 aattctttta ggcaaatgtt aatataataa tacaaaatag tataaataga agacatgtta
    21481 ctggtaatgc aggcaggatc gaatatattg ctttgatttt tcaaggtgtt tatataggtt
    21541 ctgccttttt tgcatcttga atggccattc ataaaaaatt atggagaagg agattacaag
    21601 atgaattata aaaaaactgc cattgacatt attgaacaag ttggtggttc aaaaaatatt
    21661 ttagctttag aacactgttc aactagacta cgctttaagt tgattgatag aagtaaagtc
    21721 aatcaggatg ctttaaaaaa agtacaaggt gttatgagta tagttaatgg ggcacaattt
    21781 caagttgtca ttggaaatag tgttgttgat gtgtatgatg aaattttaaa agtttgccct
    21841 ttagatacaa atgatagtac tgtaaaaact gaagaaaaaa taaacttagg aacaagattt
    21901 atagaattta ttattaatat ttttcaacca ctgatttttg ctattgcagg agctggtatt
    21961 ttaaaatcac tgttgatgtt attagcaatg tttaatattt taaaatcaga ttctactata
    22021 tatacattat tagttgctat ttcagatgca acattctatt tcctacctct tatggtagct
    22081 gtaactactg ccaatgtatt gaaatgtaat cgtttagtag ctattgccgc tgtaggatac
    22141 ttattgcttc cagcaacaac aactgcttta agtgaaggtg tcgaactatt tggatttaca
    22201 attccaaaca ttgcctataa tgcacaagtt ttcccggcta tcttatgtgt gtcttttttg
    22261 gcaacaatgg agaaaatttt taacaagtat tcaccaaaac caattcgaac tttctttgtt
    22321 cctatgatgt ctttggcaat tactgttcca attactctaa ctattttagg tcctttagga
    22381 tataacgttg gtacaatttt tacaaccatt attttattct tatataacaa aatgggattc
    22441 ttagttgtag gattacttgc tgcttttctt ccatttatgg ttgcaacagg aatgcacaaa
    22501 gcactaatac cttattcaat taatacaatt ggaaagttgg gttatgaagc tttatatatg
    22561 acatcttcat tagcccacaa tatttctgaa agtggtgctt gttttgcagt agccttgcga
    22621 acaaaagatg aaacattaaa acaaacagca ttatctgcag gaatttctgc cttgatggga
    22681 attacagagc cagctttata tggtattact ttacaacata aaagagcaat gttaggtgtt
    22741 gtattctcaa gtgcaatttc tggtacattt ttaggattat ttgcagtaaa aggatttgta
    22801 attgttggac cagggcttgc cagtatgagt atgtttattg acccaaacaa tggaaacaat
    22861 ttgatttttg cgagtattgg ttttgttatt gcaatattag gctcgtttat tattacactg
    22921 attatttgga aggaagatac aaatacagta gagtcatcaa ttggagatgt tgttgaagaa
    22981 gagctagaag aagaaaaaga agtaaatatc ttagtaactc cagtagaagg aaaagtaata
    23041 gatttaagta aggttaatga tgaactattt gcaagtaaga ctttgggaga tggagttgca
    23101 attataccga ccaatggaaa tttatacgca ccttgtgatt cagaagttgt gatgttattt
    23161 gaaacaaaac atgcaattgg tttaagaaca aaaaatgggg ctgagatttt gattcatatt
    23221 ggaataaata ctgtaagtat gaatggagat ggatttaaaa catttgttaa gacaggcgat
    23281 aatgtaaaag aaggagattt attaattcaa tttgatttag acaaaatctc acatgctaat
    23341 ttagattcaa ctgttatgat tgtaaacaat aatggagcag attatgctta taaagtgtta
    23401 aaccagtctt atggcaatgt aaaaaaagga agtatcttgt ttgatgtaaa gggaggaata
    23461 taaatatgag aaagtttcca gaaggatttc tttggggagg agctacagct gctaatcaat
    23521 ttgaaggtgg ttggaattta ggtggtaaag ggtggtctgt atcagatgta gcaaaggcac
    23581 actttgatgc agatgtgaaa gactataaat ctaataatga aatcacaaca aaagatatag
    23641 aagaaggatt agcacatcct gaagatgaag taaattatcc aaaacgtcat ggtagtgatt
    23701 tttatcatca ctataaagaa gatattgctc taatggcaga aatgggattt aagacatatc
    23761 gaatgagtat tgcttggtct cgtatttttc caaatggaga tgataaagag ccaaatgaag
    23821 aaggtttaca gttttatgat gatgtatttg atgagttgat aagttatgga attgaaccac
    23881 ttgttactat gtcacattat gaaccaccat taaatatcgt tttaaactat gatggatggt
    23941 attcacgaca agttatcaat atgtttgtta ggtatgtaga aactatctgt gaaagatata
    24001 aaaacaaagt gaaatattgg cttacattta atgaagttga ttctatgatt cgtcatccgt
    24061 acactactgg tggtttagtt cgagaccgtt ttaaggataa aaactttgag gaagttattt
    24121 ttcaagctat gcatcatcaa tttgtagcta gtgcccttgc aacaaaaatt tgccatgaga
    24181 ttattccaaa ttcaaaagta gggtgtatgt taacaaaatt aacgtattat ccatatacat
    24241 gtagaccaga agatgttttg gcaactcaac aaaaaatgag aagtatttat gcatatagtg
    24301 atacgcaggt ttttggtgag tatccagtat atttactttc gtattttaaa aataataaca
    24361 ttcaaatagc aaaagaagaa catgatgatg aaattatgaa aaagtatcca gtagatttta
    24421 tttcattctc ttactatatg tcttcttgtg aggcagctga tacaactgga ttagatatta
    24481 cacctgggaa tacgttatta gctgtaaaaa atccttattt agaaatgagt gaatggggtt
    24541 ggcaaattga ttcaataggt ctacgtatat ctttgattga attatatgat agatacagaa
    24601 agcctttatt tatagttgaa aatggattgg gagctaaaga tattttaact gaagataaaa
    24661 aagttcatga ccaatataga attaattatt taaaagaaca ctttaaatgt atgttagatg
    24721 cgattatcga agatggcgtt gaactttggg gatacacttc atggggttgt attgatttgg
    24781 tcagtgaatc aacgaaacaa atgtcaaaac gttatggata tatttatgtg gatgctgatg
    24841 attatggaaa ggggacatat aatcgatata agaaagatag tttttattgg tataaaaaag
    24901 taattgaaaa taatagtata gattttaaat gaccaataga aggtgagcaa ataaaatgaa
    24961 ctacataata aagaaagttt tgaactcgag cgttgtttta gttcatgatg caaagtataa
    25021 tgaatttatt ttgctaggga aaggaattgg atatggtaaa aaaacaggag aatatatttg
    25081 tggttccaat gataatcaaa tgtttgtccc tgttgaaaat acaaaatcaa aaaaattttt
    25141 agaattaatg gatgatattc ctgtcgacat tttaaagata acacaggaaa taatagtaga
    25201 ggcagaaaag ttattgaact catcttttaa taaaaactta tacttaatat tagcagacca
    25261 ttttaacttt gcaattgaaa ggatgcgtaa aggaataaaa attacaaatc gagtattttg
    25321 ggaaataaaa aattattatc caaatgagtt taaggttgga atggttgcaa tttatatggt
    25381 agaggagaga ttgggcattc aattaccaga ggaagaagca gctaacattg ctttccattt
    25441 tgcaaatgct atggcttcag atggaaattc atatgatacg attaagtatg ccaaagtaat
    25501 tggagaaata attaatattt ttgttttttc tttgaataga accttagata aaaagagtat
    25561 gcattatatg agatttataa cacatataaa attttttgtg gaaagatttt tttcagatag
    25621 tatgttaagc agtggtgatg atttattatt taatcaaatg aaaaggtcaa atccaaaaga
    25681 aatgttaatt gcattaaaag ttagagattt tttagaaaag aaatatggaa aaaagttaac
    25741 aaatgaggaa atagctttct tggttgtcca tatcgcacga gttaagcaat agagtgaatt
    25801 actaatatta tcttatacgt ctacatggta gaaaattgaa agaaggtaaa gtatataaag
    25861 aaactgagac atattatttt gttgttcatt atgtttattt tatgagtgta tcctgttaaa
    25921 aatttaagtt aatatttata attaaaatat ac
//
LOCUS       DAEQJM010000054        23736 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.054, whole genome shotgun sequence.
ACCESSION   DAEQJM010000054 DAEQJM010000000
VERSION     DAEQJM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23736
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.054"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..360
                     /locus_tag="KRQ43_002687"
     CDS             <1..360
                     /locus_tag="KRQ43_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH2743033.1"
                     /translation="KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQ
                     AAYNGLKEAGIDSEITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQL
                     FKGAEGYYGILKSVYKK"
     gene            376..1959
                     /locus_tag="KRQ43_002688"
     CDS             376..1959
                     /locus_tag="KRQ43_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH2743034.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1987..3315
                     /gene="ssnA"
                     /locus_tag="KRQ43_002689"
     CDS             1987..3315
                     /gene="ssnA"
                     /locus_tag="KRQ43_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBH2743035.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3514..4866
                     /locus_tag="KRQ43_002690"
     CDS             3514..4866
                     /locus_tag="KRQ43_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH2743036.1"
                     /translation="MSQDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            5058..6167
                     /locus_tag="KRQ43_002691"
     CDS             5058..6167
                     /locus_tag="KRQ43_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2743037.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6450..7841
                     /gene="hydA"
                     /locus_tag="KRQ43_002692"
     CDS             6450..7841
                     /gene="hydA"
                     /locus_tag="KRQ43_002692"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH2743038.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7835..10396
                     /gene="xdh"
                     /locus_tag="KRQ43_002693"
     CDS             7835..10396
                     /gene="xdh"
                     /locus_tag="KRQ43_002693"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HBH2743039.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETASLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10548..11894
                     /gene="rpoN"
                     /locus_tag="KRQ43_002694"
     CDS             10548..11894
                     /gene="rpoN"
                     /locus_tag="KRQ43_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBH2743040.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            12691..13713
                     /locus_tag="KRQ43_002695"
     CDS             12691..13713
                     /locus_tag="KRQ43_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH2743041.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            13773..14780
                     /gene="gap"
                     /locus_tag="KRQ43_002696"
     CDS             13773..14780
                     /gene="gap"
                     /locus_tag="KRQ43_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH2743042.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            15002..16204
                     /locus_tag="KRQ43_002697"
     CDS             15002..16204
                     /locus_tag="KRQ43_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBH2743043.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKANNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            16230..16973
                     /locus_tag="KRQ43_002698"
     CDS             16230..16973
                     /locus_tag="KRQ43_002698"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBH2743044.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLSK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            16982..18514
                     /locus_tag="KRQ43_002699"
     CDS             16982..18514
                     /locus_tag="KRQ43_002699"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBH2743045.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFANKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
     gene            19102..20394
                     /gene="eno"
                     /locus_tag="KRQ43_002700"
     CDS             19102..20394
                     /gene="eno"
                     /locus_tag="KRQ43_002700"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBH2743046.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTERLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            complement(20514..20942)
                     /locus_tag="KRQ43_002701"
     CDS             complement(20514..20942)
                     /locus_tag="KRQ43_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH2743047.1"
                     /translation="MNPVKELNNLWHIVSMQMKTEMCSGKYPTIHGISLVELSILEIV
                     EQYPNSMMKEISEILELPKSTLTSAVKRLELKKFIKKNPCIKDKRRYNLVLTELGLKA
                     QQEHRDIEIIVFRNLLHQLDKDEIETFIRIFSKAVNKSKK"
     gene            21027..21533
                     /locus_tag="KRQ43_002702"
     CDS             21027..21533
                     /locus_tag="KRQ43_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2743048.1"
                     /translation="MNLEIIRATSENAIEMGFIHSCSWRKAYKGIIPDKIIDEFTSEK
                     RAEVFQSVIPKAEEEYYLFKVNGIPAGFASLNRSQEDNAPKCVGEIYSIYFHPDFWGT
                     SVTKKGLQFCIDRLSNLGYSYITIWVLKDNTRAINFYKKNGFTCDDFEKEIHIGKKLL
                     EVRYSKKI"
     gene            21651..21875
                     /gene="secG"
                     /locus_tag="KRQ43_002703"
     CDS             21651..21875
                     /gene="secG"
                     /locus_tag="KRQ43_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBH2743049.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(22259..23197)
                     /locus_tag="KRQ43_002704"
     CDS             complement(22259..23197)
                     /locus_tag="KRQ43_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH2743050.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIRH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKTIILGVCGKLILVPSIFLPISIFLGFRNVELTSLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(23185..23583)
                     /locus_tag="KRQ43_002705"
     CDS             complement(23185..23583)
                     /locus_tag="KRQ43_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH2743051.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSEKYKLKARNVK
                     INLNIKGYKFLPYVKNLKASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
BASE COUNT         9403 a         2755 c         4554 g         7024 t
ORIGIN      
        1 aaagaagacc cagaattaaa tgcaaaagtt tcttatgcag ttgaaaaagc tgattgctat
       61 acaggaaata ctatagaaag tgaaagattc ttcccaggtt ggttatatga tgaagaagat
      121 gaatttgttc aagcagcgta taatggatta aaagaagctg gaatagattc agaaataact
      181 caatactcat tctgtacgaa tggaagtcac tacgcaggtg aggctggaat aagaactata
      241 ggatttggtc cttctaagga aaatcttgct catacaatag atgagtatat agaattagac
      301 caattattca aaggtgcaga aggatattat ggtatattaa aatcagttta taaaaaataa
      361 ttaggagatg gttttgtgag aactttaata aaacatgggc ttatagtaga tggaaataaa
      421 acaccagcat atgaaggaga tattttaata gaaaacgaga aaatattaaa aatatcacaa
      481 gatttaaacg aagaagctga caaagttata gatgcaaaag gtagagttat atgtccaggt
      541 ttcatagata ctcatagcca ttcagaccta gttattttag ttaatccata taatgaggta
      601 aagattagac agggaattac aacagaagtg ttgggccaag atggtatatc tatggcccct
      661 ctacctcaag agcatatatc ttcttggaga aaaaatttag caggtctaga tggtgaaagt
      721 gatgaaattg attggaaata tgaaacaaca gagaattatt taaaaatgat ggattacaat
      781 ggggtaggtt taaatgaaac ttatttagta cctcatggaa acgttagaat ggaagctatg
      841 ggacttgaag atagacctgc tactaaagaa gaaattcaaa aaatgtgtga aatcacagag
      901 agagaattaa aagcaggagc tataggattg tctactggac ttatatatat accttgtgca
      961 tactcattga ctgaagaaat tatagagatg tgtaaggtag tagcaaaata tgacggagta
     1021 tttgtagttc accaaagaag tgaagcagat acaattttaa cttcaatgga agaaatcata
     1081 gaaattggaa aacaatcagg agtaaaagtt catttttcac attttaaggt ttgtggtaaa
     1141 gcaaactgga agtatatacc acaagttata gagcttttag aaaaagcaga aaaggaagga
     1201 ataagagtat cttttgacca atatccatat gcagcaggaa gtacaatgct tggagtagtt
     1261 ttacctcctt gggcacattc tggaggaact gataagttaa tagaaagatt aagcgatgaa
     1321 aacgaaagag caaaaatgaa aaaagatata gcaaatggaa tagaaggctg ggataatttt
     1381 atagaatttg ctggaataga ccaaatattt gtaacaagcg taaaaacaga aaagaataaa
     1441 gatacaattg gtaagagctt attagaaatt ggaaaaatga gaggaaaaga cccattagat
     1501 gcaacgtttg atttattaaa agaagaagaa aatgcagttg ggatggtaga tttctatgga
     1561 ttagaagaac atataatagg attcatgaaa agagacgagc aaaatgtgtg tacagatggt
     1621 cttttagcag gtaaaccaca tccaagagct tatggttctt tccctaaaat actaggaaga
     1681 tatgttagag agttgaatgt actaacaatt gaagaagctg tttataaaat gactaaaaag
     1741 gcagctacaa gctttagtat aaaagataga ggcgaattaa aagaaggata ttttgcagat
     1801 atagttatat ttgacaagga tacagttagt ggttgtgatg attttatcaa ctctatgcag
     1861 taccctacag gtatagatta cgtaattata aatggaaatt gtgttgttga agaaggaaaa
     1921 tacaataaaa ttaaagcagg aaaagtactt aaaaattaaa tcttagcttt aaggaggaat
     1981 aaatttatga ttttagtggg gaatgggagg ctaataagcc aagattcttt aaatccctat
     2041 atggaagatg gatgtgtagt aataaatgat aatctaattg aagatatagg tactacagaa
     2101 gaaatgaaag ctaaatatcc agtacatgaa tttatagatg caggcaagaa aataatcatg
     2161 ccgggtctaa taaattcaca tatgcatata tacagctcat ttgctagagg aatggcagtt
     2221 ccaggaaaac cttctgagaa ctttttagag atactaaata atttatggtg gagacttgac
     2281 aaacagctta cactggaaga tacaaaatac agtgcatatg caacgtatat agaatgcata
     2341 aaaaatggtg taacaacagt ttatgaccat catgcaagtc caaatgcaat tgaaggcagt
     2401 ttgtttacaa tatcagatgt tgcaaaggat ttgggaatta gaacgtgtct ttgttatgaa
     2461 gtgtctgata gagatggtgg aaatacaatc caacaaggta tcaatgaaaa cgtaaacttt
     2521 ataaaatacg ctcaaaaaga tgatacagac atgataaaag gaatgtttgg gcttcatgct
     2581 gcatttacac tatctgatga tacattaaat aaatgtgctt cagagatggc tggtcttgat
     2641 acaggttacc atgtacatgt tgctgaagga ctagcagact tacaatataa tgtagataaa
     2701 tatggaaaaa gggttttaga aagattcaat gattttggag tactaaaaga aaaaacaata
     2761 gcagttcatt gtatatatat aagtgcagaa gaaatcagtc ttttaaataa aacaaataca
     2821 tttgtagttc ataatccaga atctaatatg ggaaatgcag ttggatgttc tcctgcaata
     2881 gagttattaa aaaggggagt tacagtagga ttaggaactg atggatatac tagcgatatg
     2941 tttgaatcat taaaagttgc caatataatt cacaaacatc acttaaaaga cccaagagtt
     3001 ggatttgaag aatcacaaac aatgttattt gataacaata gaaaaatagc taaagcttat
     3061 tataaaaatg acctaggagt acttaaaaaa ggtgcttatg cagatgttat agtagttgat
     3121 tatataccac atactccatt gacagaaaat acaatagggg gacacactat ttttggaatg
     3181 agtggaagaa gcgtagatac aactattata aatggaaaag tacttatgaa agatagaaag
     3241 ttaataaaca tagatgaaga aagtattcta gcaaaaagta gagaattaag tcaaaatcta
     3301 tggaatagaa tttaaataat tgattatgca aaattctatg aagcaggaac cctgtgactt
     3361 tagtcatggg aggttcagat taatatacaa gtaagaaaca agaatttaga tgttaaaaac
     3421 agagcttaaa caaaaatagg aatttaaatg aagtatataa ataaaaaata tacggaatag
     3481 aatattaaat taaatataga agggagaccc aaaatgtctc aagataaaag ccctaaaata
     3541 gctccagtag atgaaaggtt acctgtatcc aaatcttggg tattttcact acagcacgtt
     3601 ttagcaatgt gtgcaggagc agtagcagtt cctatgatga taggaagtgc tgcacgacta
     3661 gatcatgcta gtattgtttt tttaataaat gcttgcttgt ttatggcagg tataggaaca
     3721 ctcatacaaa gtgttggtat aggaaatatt gtaggtgcta aaataccagt aatagaagga
     3781 actagttttg ccgctgtggc aggtatgaca gcaatagcct catcatatag tgattcacaa
     3841 gttgcaatac agacagtatt tggctctgta atagtagctg gattgttttg tatattactt
     3901 gctccagtat ttgaaaaatt aataagattt ttccctagtg tagttactgg aacagttgtt
     3961 atggtaatag gtatttcact atttccagtt gggataaaat ggataactga caacaaattg
     4021 gaagcggttg aaccaaactc attagcatta gctttagcag tattggcaat aactttactt
     4081 tcatttaaat tcttaaaagg aatttggaat agcacagcta tattggtagg tatagtactt
     4141 ggtacactac tttccatggc agttggaatg gcagatttta gtgcagtaaa tggagttggt
     4201 tggcttaact taaatgtacc tttaaaattt ggaatgccta gatttgaacc atctgcaata
     4261 ctatcattgt gtttgattat gttggtactt atgacggaat cagttggtaa tatgatagct
     4321 attcatgaaa tggtagacaa agaagtaaca ggtaaaaata ttaaaagagg tctatttgga
     4381 gatggaatat ctacagcatt atctggaata ttcaattcat ttccaataac tccatttggt
     4441 caaaatacag gaatagtagg tcttacaggt ataaaatcaa gatttatagc agtttacgca
     4501 ggggttatat tgctagtact tggattctta ccaaaatttg cagcaataat aggagcaata
     4561 cctaagcctg ttctcggagg cgtaggattt gcaatgtttg gaatggtaat ggttggagga
     4621 gtaaaaactt taagcaaagt gaaatttgat ggaactaaaa atggggttat agtagcagtt
     4681 agtgttggtt tgtctatgat accactaaca aatcccgatt tctatcataa tttcccaact
     4741 tgggtacaaa caatattcca tagtggaata acaacaggta gtttatcagc agtgctttta
     4801 aacatattct tcaatgaact aggttctaaa aaagaaaaaa ataataaagt tgaagaagca
     4861 aaataaaaat aaaacaagta aaaatctata ttgacttaaa gtcattaagc attaataaaa
     4921 ataattcaga gatattaata attcaacaaa actatcttat attttaaata atataaaaaa
     4981 gtaaataaat aacgaataca aataaaagaa tacaatctaa atattaaaaa tatttaattt
     5041 aagggagaga taataatatg gctaatttaa aagttaattt atatggaatg gaatttttaa
     5101 acccaattat gacagcggca ggacctggag caaaagatgg tgctctctgt caagaggcag
     5161 caaaaggtgg agcaggagct atatgtacaa aaactatatc tgtattacca gctgatgtac
     5221 caagaccatg tatggcaaaa actaatagtg gttttttaaa cacagaatta tggtcagagc
     5281 ttccaaaaga gcaatggata gaggaagaat acaaaaaggt aaaagaaaca gggcttccag
     5341 taatagtaag tatgggatat tcagcagagc aaatagctga ggttgctcct ttagtaaagc
     5401 cttatgcaga tgcagttgaa ttatctactc attatgtagg tacagacgtt gcaccaatag
     5461 taaatgcttt aaaagctgca aaagctgttt tagatgtacc agtatttatg aaaatgagtc
     5521 ctcatactga cattcaaact attgcaaaag ctgttgaaga agcaggtgca gatggacttg
     5581 taatgataaa ctcatttgga ccatgtatgg caatagatgt aaatacagga taccctataa
     5641 tgggaagtaa agctggatac ggatggttat caggtgcacc aataagacct ctagcaataa
     5701 gatgtatata tgaagcttct caagttgtaa atataccaat aatcggtgtt ggtggaatca
     5761 cttgtggaaa agacgtggct gaaatgatga tggctggagc aagtgctgtt caagtatgta
     5821 cagaagcaat ccttaaaggg ccttctatct atggaaaaat tgctaaagaa ttaaatgaat
     5881 ttttagatga gaatggatat gctgatgtta atgaaataaa aggattaact cataagaaaa
     5941 tggcagctag agggtttaga actcattcag tagctccagt agtggatgat aacaagtgca
     6001 tcaaatgtaa gcaatgtgta acaagctgtg tatacgaagc tttagaagtt acagataagt
     6061 tgaacataga tgcagacaag tgttttggat gtggattatg tgtaactaga tgtccaaaag
     6121 gagctttaag catctgctac aatcaagtag aagctatgaa tgagtaataa ttatatagaa
     6181 ttttggtaat taacttagag taataggtat taggataata aaatatatca gataaacaaa
     6241 cacacattat gcattaataa tacagtctaa agttaataat tttattatat tgatttaact
     6301 aaatattagt ttagctgaat attaatttaa ttaggtattg gtttaatctt aatatagatt
     6361 tactacgtat aagtgaacta actagattac tttaagttaa ttttttcata taaaataaat
     6421 tgatacatta caagtaaggt ggagtctata tgggaattgt tttaaaaggt gggaaagtag
     6481 taacaagtga aaaaacttac tgtgcagatg taagaataga agatgaaaaa atagtcgata
     6541 taggtcttga tatatcaaaa gaaaatgatg aaatagttga tgttagtgat tcttatgtta
     6601 taccaggagg tatagataca cacacacact ttgacttaga tacaggcgtt actaagacag
     6661 cagataactt tgagacagga acaaaagctg ctatagtagg aggaactact actatattgg
     6721 attttgctac acaagctaaa ggatgttctt tgaaagacgg attagaagaa tggcatgaaa
     6781 aagctaagga taaatcctat tcagattatg gctttcatat ggctataaca gattggaatg
     6841 actcggtttg taatgaaatg gaggatatgg tgaaagaggg agtatcttca tttaaactgt
     6901 atatggcgta taaaggaagc cttcaagttg atgatggtgt aatctttgaa gcattgagaa
     6961 aagcagaaga gataggaggg attattggtt tccattgtga aaatggggac ataatatgtg
     7021 aacttgtgga taaagcaaag tcagaaaata atttatctcc aaaatatcat caattaacta
     7081 gaccagctat aatggaggca gaagctacat caagacttat gaagatagct gaagttgcaa
     7141 actcaaaagt atatgtagtt cacttaagct gtaaagaatc cttagaggag gttttaaaag
     7201 ctaagcaaag aggtgtggat gtaatagttg aaacttgtcc tcaatacctt ctattaaatg
     7261 atgaattata tgatttagat ggatttgaaa gtgctaagta tgtaatgtca ccacctttaa
     7321 gaaataaaga aaataatgaa atattatgga atgctatttt agataatcaa atagacacta
     7381 taggaacaga ccattgttct tttaattata agggacagaa ggaacttggg ataaacgatt
     7441 tcagtaagat accaaatggt tctccaggtg tagaacatag gatgagtctt ttatacacat
     7501 atggagtctg taaaaataaa atatctatca acaagatggt agaagtaaca tcaactaatg
     7561 cagcaaagtt gtttggaatg tatcctaata aaggaactat agaaataggc agtgatgcag
     7621 atatattagt cttaaatcca aacaaaaaat ccaaaataga agcaaaaaaa caattacaaa
     7681 atgtagatta tacaccttat gaagggtatg aagtggattg tcaaatagaa catgtttatt
     7741 taagaggaaa agaagtagtt agagatggag aattaatttg taatactcca agtgggagat
     7801 atataaatag gcgtctaaca aagggggcta gagaatggta gaatttatat taaatggaga
     7861 gaaagttgtt gcaaaagaag gcaaaaaact tttagacttc cttagagaag atatgaatat
     7921 aacttcagtt aaaaatggct gttcagaagg tgcttgtgga acatgtatgg ttataataga
     7981 tggtaaagct actaaagcat gtgtatttaa aactgataaa ttagctggga aaaacataac
     8041 aactatagag ggattatcag agagagaaag agatgttttt gcatattctt ttgctagtca
     8101 aggagctgta caatgtggat tttgtattcc aggtatggta attagttcaa aagcacttat
     8161 agatgttaat aataatccta ctgaagatga tataaagaaa gctttaaaag gtaatatatg
     8221 tagatgtaca gggtatgtaa aaataattaa agctgtcgat ttagcagcaa agatttttag
     8281 agaaaatata gatgtgccaa aagtaaactg taagggtcta gtaggtgaaa atcttcctag
     8341 agttgatgca gttggcaaag cacttggata ttctgaatat gtagatgata tgagaattga
     8401 gggtatgatt tatggttcag cagttagagc taagtatcct agagctttag ttaaaaaaat
     8461 agatatagaa gaagcaaaag cttatccagg agttgttgca gttctaacag ctaaagatat
     8521 tccaggaact ataaaggtag ggcacttaaa gaaggattgg gatactttaa taccagaagg
     8581 tgaaataact agatatttag gagatggaat agttttagta gcagcagaaa ctagagaagc
     8641 gttagaagag gccaaaaagc tagttaagat agattatgag gaattaacac cattaagtac
     8701 tacagcagat gcacttagag aagatgctcc aaagatacat gagacaggga atatacttgt
     8761 taaggaacat ttagtaagag gaaacgctaa agaaaagata gaaaattcaa aatatgttgt
     8821 aactaaaaga tatactacac ctgctacaga acacgcattt ttagagcctg aatgtgcagt
     8881 agctggtcct tatgaagatg atggagtaat aatctattca acagaccaag gggtgtttgc
     8941 cactcaacat gaatgtgcag atatgttagg gttaccatat gagaaggtaa gagttataaa
     9001 caaaatggta ggaggagggt ttggtggaaa agaagacatg agtgttcaac accatgcagc
     9061 cttacttgca taccatacaa agagatttgt aaaagtacag ttaacaagaa aagaaagtat
     9121 tattgttcat ccaaaacgac atgccacaga aatggaattt acgacagcat gtgatgaaaa
     9181 tggatactta acgggtatga aggcaacgat aatatctgac acaggtgcat atgcctctct
     9241 tggaggacca gtgctacaaa gactgtgtac tcatgcagca ggaccataca attatcaaga
     9301 tattgatata acaggaacag cagtatatac taataaccct cctggaggag catttagagg
     9361 atttggagtt acacagagtt gttttgcaac tgaatgtaat ctaaatttac ttgctgaaat
     9421 ggttggaata tctccttggg agataagata taaaaatgca ataagacctg ggcaagtttt
     9481 accaaatggt caatttgcag atgaaggaac agcaatggca gagacactag aagctgtaaa
     9541 agaagagtat gaaaagcatc cacgtgcagg tatagcttgt gctatgaaaa atagtggggt
     9601 tggagttggt atacctgatg ttggaagatg tagattggtg ataaaagatg gcaaagttca
     9661 cataagaaca agtgcttctt gtataggtca agggcttggt actgttatga ctcaagtagt
     9721 ttgtgaaact gctagcctac ttcctgaaaa tatagtgcat gaagttccag atactcattt
     9781 aacaccagac tctggtaata ctacggcttc aagacagaca gtatttacgg gagaagctac
     9841 taaggttgca tcaaataagt taaaagaagc tttagactct ggcaaaactt tacttgattt
     9901 agagggagaa gagttttatg gagaatatga aagtattaca gataaaatgg gttgtgacaa
     9961 agaaaatcca gtaagtcatg ttgcttatgg atatgcaaca caagttgtaa ttctggatga
    10021 aaatggaaaa ctagaaaaag tagtagcagc acatgatgtt ggaagagcta taaatccaat
    10081 cagtttagaa ggtcaaatag aaggtggagt agttatgggt cttggatatg ctctaaccga
    10141 agattaccca gtagttaact ctgttcctac agctaagttt ggtacattag gtttatttaa
    10201 atctacagat ataccagaaa tacaagcttt aatagttgaa aagaacaaag atttattggc
    10261 ttatggggca aaaggtgtag gagaaatttg tacagttcct actgcaccag cagtacaaaa
    10321 tgcctattat gtatttgata aagaatttag aactgagcta ccactacaaa atactccata
    10381 tagtaaaaaa aagtaacaaa aaaaagaaat attaaataaa aaaatagatg aaattgtaaa
    10441 taaaaaaaac ccttttgcat aaggtatatt ttaaatgata gaatatacat atacaggagg
    10501 gtttttcttt tataaaataa gtttaataaa attgagaggt gagcagaatg aattttaata
    10561 atagtctaga attaactcag tctcagaagc taataatgac tacacaactt aagcaatcat
    10621 tatcaatatt aaatatgagt aagttagagt tagaagaaga gataaaaaga gaagcagaga
    10681 ataacccatt agttgaagtc gagaaaagtg gggagataaa ttgggaagag tatataaaag
    10741 acatggatag gtcaagacgt ttagatagaa cagagataag ctataatcct gataatgaag
    10801 ttaatctaga aaatttagtt aaatattcgt caaatttata tgaagattta aaatttcaga
    10861 taagcctgta taaacttaca gacaaagaat tggaagtctg tgagtatata attgatagtt
    10921 tagatgagga tggatattta agaactgagg aaaaagtaat tgttgatacc ttaaagatag
    10981 atgaagaact ttttgaaaaa tgtttaatta gtgttcagca gttggaacct agtggagtag
    11041 gggcaagaag tctttcagaa tgtctgatga tacaaatggc tagtttagga atatataatg
    11101 aaattttaga ggaaatcgtt acaaaagact taaatttaat tgcaaataat aaatataaag
    11161 agataagtaa aaagtacaat atgtcattac aaaaatgtgt tgaactaata aacataatta
    11221 agacattaga ccccaaacca ggaagaactt gttcagtaga gaaaagtgta tacattcaac
    11281 ctgatgtaac agtagaaaag attgatgatg aatttattgt atatttaaat gagaaagatt
    11341 cttaccaaat aagaatcaat agttattata aagacatatt aaaaaattca cagtctgatg
    11401 aaagtgcaaa agaatttata aaagaaagac taaattcagc aacaggactt atgaaaaata
    11461 tagagagtag gaaaactaca gtacttaaga ttgcagaaga gatagtaaaa gctcaagatg
    11521 aatttttgag aaaagggaca aaatatataa aacctttgaa aatgaaagac atagcagaaa
    11581 aattagaatt tcatgaatct actataagta gaggtgtaaa tggtaaatat atgctaacac
    11641 cttttggcgt atatgaattt aggtactttt tcagtagcgc cattgagact gagaataatg
    11701 aaatggcatc tagtacaagc ataaaaaaaa ttataaagga aacaataaaa gacgaaaata
    11761 aaaagaaacc tttaagtgat gaccatatat ctaagttatt aaaagaaaaa ggaatcaatg
    11821 ttgcaagaag gacagttgcc aaatatcgtg aagaattagg aatcccatct tcaagtaaga
    11881 gaaaagaata ctaataagta aaagacaaat atcagtatgg taaggggaaa aggctaatta
    11941 agagatgaat gtagattggg ctaaaaattt tataaagtaa aataatagaa tatggaaaag
    12001 tattaaaatg ctataaggta ttaaaaaact ggggaacatt aaaacattaa gatagcaaag
    12061 aacataaaaa actaaagaag attaaaacat taaagaacat taggctttga ggaatattag
    12121 aactttaaag aatattaaaa tttataaaat ataaaaatac taaaaagaat tgaaaaactg
    12181 gggaacatta aaatattgta aaatgctaaa aaactagaaa acataattaa ataagtgctt
    12241 ataaagaatg attaaattaa ataagtgttt gtaaagaata attagatatt agaaaaagaa
    12301 gaatacctag ataaataaac tattattaaa tttaataatc acaaaaggaa aacacgtagg
    12361 gtataaataa aaatcttaac tagataaaag taaacttagt tgtagataaa aataactaga
    12421 aataaaagta actagaaata aaattattta tagtaataaa tattagaatg aaaatataaa
    12481 aaaatatata taaaaagcct tatataaaaa gaaaaaatac tgtgatttga aaatggtgga
    12541 gaaatatttt ataaaataaa aaaataaaaa agtttttgaa aaactattga aatctatacg
    12601 caaatcctat aaaataaaaa tatcttgtgg gacttaaata aacactaggg acaaaaaaag
    12661 tcccgaaagg aaagcaataa ggagtatgtt atgaagaact tattagaaat tcaaaagaaa
    12721 ttgattccac aggcaattga acttatggaa agaagatact ctattttaag acaaatatct
    12781 ttaagtgaac caataggtag gagaacatta tcaaatgtat tagagattag tgaaagaata
    12841 atcaggtcag aaactgagtt tttaaaagaa caaggactta tagacgtagc tgtatctggg
    12901 atgactatca ctaaagaagg ttctgatttg ttagataaac ttaaggacat catgagtgac
    12961 atcatgggat tgtctaagtt acaagataga gtcagagaaa agcttggaat aaaaagggta
    13021 atactagttc ctggaagctg tgatgaaaat ggaagtttac taaaagatgt aactagatat
    13081 ggatgcgagt atttcttagg cattttaaaa gatggagata tcgtttcaat aacaggagga
    13141 agcactatgt tggagttttc aaacgttatt aaaactgata agagatatcc aaactctaca
    13201 atagttccag ctagaggaag tatgggaact gatgtagaga tgcaatctaa caatatagtt
    13261 gcttcaataa gtaagaaatt acattctaat tgcaaacttt tacatatacc agatgagttg
    13321 gatgaaagtg caatgaaaac tcttagccaa gtgccagaga ttaagacaac tttggagtat
    13381 attaaaagaa cagacatttt agtttttagt ataggtagag cagatgtcat ggcaaagaga
    13441 agaaaacttc cagaagacaa ggttgatgag atattatcta aaaatgcagt tggagaagca
    13501 tttggatatt atttcaacaa agatggagaa atagtttaca aactgaacac tgttggaatt
    13561 gatttagaaa cagttaaaca agtaaaagaa actattgcaa tctttgcagg gactgaaaaa
    13621 gtagaagcct tattagctat atcaaatatg cataaaaaca tggttcttgt aacagatgaa
    13681 gaaagtgctt ataagatatt gtcattatta taaaagtcaa gacctagcac agagctagaa
    13741 aacatacatt tactttatag gaggtagcga aaatggttaa agtagctata aatggatttg
    13801 gaagaatagg aagattagca ttaagaaaaa tgatggagca acaagataag ttcgaagttg
    13861 ttgcaataaa cgacttaaca gacgctaaaa tgttagctca tttatttaaa tatgatacag
    13921 ctcaaggaag atttaacgga gaaatagaag ttaaagaagg tgcttttgta gtaaacggaa
    13981 aagaaataaa agtaacagca gaaagaaatc ctgctgacct accatgggct gaattaggag
    14041 tagatatagt attagaatgt acaggattct ttacatctaa agataaagct gaagctcata
    14101 tacaagcagg ggctaagaaa gttgttatat ctgcaccagc tactggagat ttaaaaacaa
    14161 tagtattcaa cacaaacagt gacatattag atggttctga aacagttata tcaggagctt
    14221 cttgtactac taactgttta gctccaatgg ctaaagtatt aaatgataaa tacggtatag
    14281 aaaaaggatt aatgactact atacatgcat acactaatga ccaaaatact ttagatggtc
    14341 ctcatccaaa aggtgattta agaagagcta gagctgctgc tggaaacata gttccaaaca
    14401 ctacaggagc tgcaaaagca ataggcttag taataccttc attaaaagga aaattagatg
    14461 gggcagcaca aagagtacca gttgtaactg gttcaataac tgaattagtt tgtacattag
    14521 gaaaaaatgt tacagttgaa gaaataaatg cagctatgaa agaagcttca aacgaatctt
    14581 tcggatatac tgaagaaatg ttagtatctt ctgacataat cggaataagc tacggttcat
    14641 tatttgacgc tactcaaaca aaagttatgg aagtagatgg aaaacaatta gttaaagttg
    14701 tttcttggta tgataatgaa atgtcttata cttctcaatt aataagaact ttaggatact
    14761 ttgcacaatt agcaaaatag tcagttttga gaaaatagaa aagtagattg acaaagtccg
    14821 agtttgtagt ttaatactac ggactcagga ctttttttaa gaaaaaatat ataaaataca
    14881 cctaaataat gttacatact atatataaaa atatgataat atgatatatt taatagggta
    14941 aaagtatgta ctatattata cttggcaata aaaaattact ttattaaaag gagagatatt
    15001 tatgtcaatg cttaacaaaa aaactataga agatattgat gtgtgcggaa aaaaagtatt
    15061 agtaagatgt gactttaatg tgccattaca agatggtgta attactgatg aaaatagatt
    15121 gaacggagct ttaccaacta ttcaatattt aatttctaaa ggggcaaaag ttatattatg
    15181 ctctcactta ggaaagccaa aaggagaagc taaaccagaa ttatctttag caccagtagc
    15241 aaagagatta tctgagatgt taggaaaaga agttgtattt gcagcagacg ataatgttgt
    15301 aggagaaaat gcaaagaaag caactgaaaa aatggaaaac ggagatgtag tattattaga
    15361 aaatactaga tatagaaaag aagaaactaa aaacgaagag aatttctcta aagaactagc
    15421 atcacttgct gaaatatttg taaatgatgc atttggaact gctcatagag cacattgctc
    15481 aacagttggt gcaggcgagt ttttacaaga gagagtttgt ggatacttaa ttcaaaaaga
    15541 attaaaattc ttaggagaag ctgttgcaaa ccctgtaaga ccatttacag ctatacttgg
    15601 aggagctaaa gtttctgata aattagctgt tataaacgaa ttattagaaa aagttgataa
    15661 tctaataata ggtggaggaa tggcttatac attcttaaaa gctcagggtt atgaagtagg
    15721 aacttcttta cttgaaatag ataaagttga atatgctaaa gaaatgatgg aaaaagctaa
    15781 taataagggt gttaacttat tattaccagt agacgttgtt atggcagacc actttgcacc
    15841 agatgctact ccaatagtaa cagaagatgc taatgtaaaa gaagattaca tgggactaga
    15901 tatgggacct aagactatag caaactttgt aaaaactata aaagaatcaa aaactgtagt
    15961 atggaatggg ccaatgggag tatttgaatt tgaaaacttt gcaaatggta cattatcagt
    16021 agctagagct atggcagagt tgactgatgc aactactgta attggcggtg gagatagtgc
    16081 agcagcagtt aatcaattag gatttggtga caagatgact cacgtatcaa caggtggagg
    16141 agcatcacta gaatttttag aaggtaaaga attaccaggt attgcagcat tagataataa
    16201 ataaactaat atatagagga gattgtaaaa tgagaaaacc tataattgca ggaaactgga
    16261 aaatgcataa aacaataaaa gaagctttag aatttgtaaa tgaagttaaa gataaagtaa
    16321 attctgataa agtagaagct gttatatgtg caccatttac tttattaaag gatttaaaag
    16381 aagctactaa gggtacaaat ataaagatag gtgctcaaaa tatgcacttt gaagaaaaag
    16441 gagcatttac aggagaagtt tcacctctta tgttaaaaga aatagatatg gactatgttg
    16501 taataggaca ttcagaaaga agacaatact tcaatgaaac tgatgaaact gtaaacaaga
    16561 aagttttaaa agcattagaa gtaggaatag acccaatatt atgtgttgga gaaactttag
    16621 aacaaagaga agctggaaaa actaaagatg tttgtaaagt tcaagttgaa aaagctttag
    16681 aaaatgttct taaagatgat ttatcaaaag tagttgttgc atatgagcca atctgggcta
    16741 ttggaactgg taaaactgca actgctgaag atgctaatga cgttatatct tatataagag
    16801 aagttataaa aggattatat ggagaattag ctaatgaagt tagaatacaa tacggtggaa
    16861 gtgttaaacc ttcaaatgta gccgaaataa tgggtcaaag tgatatagat ggagctttag
    16921 taggtggagc tagtttagct agtaatgatt acctagacct tgttaatttc taaggagtga
    16981 aatgatgaaa aaaccagttg ctttaattat tatggacggg tttggataca ataaggatgt
    17041 taagggaaat gcaattgctg agtccaaaac tcctaattta gatagaataa aaaaagagta
    17101 tccaaacaca ttgataaatg ctagtggtct tgatgttggt ctacctgatg gtcaaatggg
    17161 aaattcagaa gttggacaca ctaacatagg tgcaggtaga atagtatatc aagatttaac
    17221 tagaataaca aaatctataa aagatggtga cttttttgct aataaagttt tatgtgaagc
    17281 aatggataat gcaaaagaaa attctcttca tgtaatggga cttttgtctg atggaggagt
    17341 acattcacat atagaccatc ttaaggctat aatcaaaatg gcaaaagata aaggcgtaca
    17401 aaaggtgtat gttcacgcat ttactgatgg tagagatact gaccctcaaa gtgcattaga
    17461 atatgccaaa gaagtacaag ctagtatgga tgaaattgga gtaggtgaat ttgctacagt
    17521 ttctggtaga tactacgcta tggatagaga taagagatgg gaaagagtag aacttgcata
    17581 caatgccatg gttagaggta ttggtgaaaa agcaaattct attgaggaag ctattcaaaa
    17641 ctcttatgat gatggaaaaa atgatgagtt tataatgcca acagttatta tgaaagatga
    17701 taaaccagtt ggaagtataa aggaaaatga ttcaattata ttcttcaact ttagaccaga
    17761 tagagctaga caaataacta gagctttagt ttgtgaagag tttgatggat ttaaaagaga
    17821 agatattaaa aacttctttg tatgcttaac agagtacgat ataactatag agaatgtgca
    17881 tatagcattt ggacctcaat ctttagccaa cactttaggt gagtatctag ctaaaaatgg
    17941 aaaaactcaa cttagagctg ctgaaactga aaagtatgca catgtaactt tcttcttcaa
    18001 tggtggagta gaagagccaa ataaaggtga agaaagacta ttgatacctt ctccaaaggt
    18061 tgcaacttat gatttaaaac cagaaatgtc agcatatgaa ttgacagata aagctttaga
    18121 taaattagga gaagataagt ttgactttat agtattaaac tttgcaaatc ctgatatggt
    18181 aggtcacaca ggaagtatag aagcggctat aaaggctgtt gaaactgtag atacttgtgt
    18241 aggaaaattg atagataaaa tagtagagtt aggtggaagt gcaataataa ctgctgacca
    18301 cggaaatgct gaatatatgt tagacccgga aacaggaaaa actgtaacgg ctcactctat
    18361 taatccagta ccatttattg tagttggtca agaatatgaa agtgcaaaat tattggatgg
    18421 aggaagatta tctgatatag caccgactgt tttagatatg atgaagttag aaaagccaga
    18481 agaaatgact ggtcattcac ttatttcaaa atagtcgatt ctgataagta gagaataata
    18541 tataaactac aatataaatt taaaaataat gcagtttagg tttattttgt aaagtttaga
    18601 ctttatgaca taagatttag attttgtaag ttctggatat tgtaaggtgt agatgaaggt
    18661 atattttata aaatttacaa gatagacaat ttataaaata aaaaattata atatagataa
    18721 taatgtaaat aatgatataa ataataacaa gatagacaat aacaatataa ataataataa
    18781 ttaatatata ttatataagc aaaaatttta gaatcattag ttgtacattt tatgtttaat
    18841 gttttaaatc tagttataat atttgtgtat ttaagattgg ttttggattt tagacaagtt
    18901 tttttatatt atataaatta aaatattata aaaaataaaa taaaaatagg aacttttaca
    18961 aatttaccca tcaaataaat ttgtacctaa ttttcaaaag caactttatg tactataata
    19021 tagaaagtag attaaaatag tagacggatg tttacagtaa atgaaaattt aactaataga
    19081 aaatcgaagg gagatataca aatgtcagtt attgaattag tatatgctag agaagtatta
    19141 gactcaagag gaaatccaac tgtagaagtt gaagtagtat tagaagatgg agcaatggga
    19201 agagcaatag ttccatcagg agcatctaca ggagcttttg aagctgttga attaagagat
    19261 ggagataagg gaagatactt aggaaaaggt gtagaaacag ctgttgctaa cgtaaatgaa
    19321 ataatagcac ctgaaataga aggaatggat gcatttgacc aaccagctat agatgcaatc
    19381 atgatagaat tagatggaac tccaaacaaa ggtaaattag gagctaatgc tatattaggt
    19441 gtttcaatgg cagtagctag agcagctgct gatgaaatag gtttaccatt attccaatat
    19501 ttaggtggag taaatgctaa acaattacct gttccaatga tgaacatatt aaacggtgga
    19561 gagcatgctg ataataacgt tgatgttcaa gagttcatga tattaccagt aggagcttgt
    19621 tgctttaaag aaggtttaag aatgggagca gaagtattcc attcattaaa gaaagtttta
    19681 ggagaaaaag gattagcttg tggtgttggt gacgaaggtg gatttgctcc aaacttaggt
    19741 tcaaacagag aagctttaga attaatagtt gaagctataa caaaagctgg atataagcca
    19801 ggtgaagatg ttatgttagg acttgacgtt gctgctacag aaatgtacaa caaagaaact
    19861 aaaaaatacg ttttagcagg agaaggaaaa gagttaactg ctgctgaaat ggttgcttta
    19921 tatgaagatt ggtcaaacaa cttcccaata ataactatag aagatggttt agacgaagaa
    19981 gattgggacg gatggaagtt attaactgaa agattaggaa ataaattaca attagttggt
    20041 gacgacttat ttgttactaa cacagagaga ttagaaaaag gaattgaaaa tggagtagct
    20101 aactctatat tagttaaagt taatcaaata ggtacaataa ctgaaacttt agatgctata
    20161 gaaatggcta agagagcagg atatactgct gttatatctc acagatcagg agaaactgaa
    20221 gattctacta tagcagattt agctgttgca gtaaatgctg gtcaaataaa aactggtgct
    20281 ccatcaagaa ctgatagagt tgctaagtac aaccaattat taagaataga agaaatggtt
    20341 ggagaacaag ctagatactg tggattaaaa tctttctata atttaaaaaa atagttattg
    20401 aagattaaaa atatggcatt aaagattaaa aagataacat aaaagataaa aatttatctt
    20461 ataagggata agtgatagtt gatttttcaa ttcacttatc ctttttttat atttcatttc
    20521 ttacttttat tcacagcttt agaaaaaata cgaataaaag tttctatttc atctttatct
    20581 aattgatgta agagatttct aaatacaatt atttctatgt ctctatgttc ttgttgagcc
    20641 tttaaaccta attcagttaa gactaagtta tacctccttt tgtctttaat acagggattc
    20701 tttttaataa atttttttaa ttcaagacgt tttacagcac ttgttaatgt gctttttggc
    20761 aattctaaaa tttcactaat ttctttcatc atactattgg gatactgttc aactatttct
    20821 aaaatactta attctactaa agaaatacca tgaatagtag gatacttacc actacacatt
    20881 tctgttttca tctgcatact aacaatatgc cacaggttgt ttagctcttt tacaggattc
    20941 attgactttt acctccatat atgatacaat tatcgcacta atatagtacg ataatcgtat
    21001 taatttgtca ataggatggt gtttttatga atttagagat tatacgagct acaagtgaaa
    21061 atgctataga aatgggtttt atacattctt gttcgtggag aaaagcgtat aaaggaatta
    21121 ttccagataa gataatagat gaattcactt ctgagaaaag agcagaagtt tttcaaagtg
    21181 ttattccaaa agctgaagag gaatattatc tttttaaagt gaatggtata cctgctggtt
    21241 ttgcttcatt aaatagaagt caagaggata atgctccaaa atgtgttgga gaaatatatt
    21301 ctatatattt ccatcccgat ttttggggaa catctgtgac aaaaaaagga ttacaatttt
    21361 gcattgatag attaagcaat ttaggatatt catatataac gatatgggtt ctaaaagaca
    21421 atactagagc tataaatttc tataaaaaaa atggttttac ttgtgatgat tttgagaaag
    21481 agatacatat tggaaaaaaa ttattagaag tacgttattc aaaaaagata tagtaattgc
    21541 atattatttt tgtttgttat ttatacttca atagtcttga aatgactata ttattgtgat
    21601 acactaaaga gtaatgaaat ttaagtaata aatagatagg aggggcaata atgagcaaca
    21661 ttttaatggg tgtgcaagta gtgctaggga ttttactagt aattagcata atgcctcaag
    21721 attcaaaaaa tgctttacct tcagaatttg gtggagaagg aagtcaagct tactttaaac
    21781 caaaaggaaa acaagcattt cttgctagag ttacaaagat aacagcagta ttatttttta
    21841 taaatgcatt ggcattactt atagttaaga agtagtgata ttgttgaata actggccatt
    21901 atttaattag tgcatttgct agatatttaa aaattaaatt tagtttttaa taaaagtaca
    21961 tcaacataaa aagtacgtaa aataaaagct ggactaatga ttttatatga ttagtccagt
    22021 ttttatttta tagattgact atttgttggc atttattatt tgtatttata tattgtttat
    22081 atttatatat ttttttcaaa ctaaaaaata tatagcaaca ctactttcac catgtttaat
    22141 gagataatat acacaaagtt atattatata gtaaaaatag tataataata tgtttttacg
    22201 caattaaatc aattttatat atgtttctca taataccaat ttgtgttatc aaatatcatt
    22261 aaataagatt attctgcttt aaaataaata ttattaaaaa tactgtaatt atagaaaatc
    22321 cagaagtaaa tactacaatt tgtccagcta attcactgtc agaatccatc tgttgtgcca
    22381 ttgtaaatga agaaactgca gttggagcag ataacattat cataagtgaa gttaattcta
    22441 catttctaaa tccaagaaaa atgctaattg gtaaaaatat agaaggtaca agtataagtt
    22501 ttccacatac gcccaatata atggttttta tatgcccctt tatagcagaa aaactaaaag
    22561 atccgcctag aattataagt gataaaggag tagctatttt agaaatatca ccaatagttt
    22621 tgtgtaaaaa tgtaggtata ttaatattta aaattagcat tgtcaatcct ataaaagagg
    22681 cgattatgag tggatttgtt aagacgcttt taatcatatg tcttatattt actttgccac
    22741 ctctaaaaat ttcaagaatt acaacagata atacattaaa cataggtaca ataactgcaa
    22801 ttaataaaga tgtgactcca atactcttat cgccaaatag tgaaattgtc acaggaatac
    22861 caaatataac gaaattgcta cgaaatacac cttgtattaa tgcacccctt gtcttattat
    22921 ctttttcaat tttaggaata ataaagacta agattaagaa gattgaaaaa ataattataa
    22981 cagctacagc cataagctta aaattaagag aaccatctaa atctgtattg tatatattaa
    23041 aaaataataa taatggcaag aaagacttga agcagacatt attcatttta tttaaagtat
    23101 gagtatcaaa tagacctaat ttttttagaa catatccaag tgacattgtg agaaacaaag
    23161 gaagaacaac atttattgat aggattaaat tttccaaggt ttactctccg tgattctatg
    23221 atttgataat tcaattaaat ttccattagt ttttttcaaa taaatagatt tcatattacc
    23281 aaagacacct gtacattcta caattcctcg cttaatttga atctcatttt gttctaagta
    23341 tttttttggc tcatcaatat ttgtgtttat tttaaaacat aagttatctc tacttgcttt
    23401 taaattttta acataaggta aaaatttata accttttatg ttaagattta tcttaacatt
    23461 tctagcctta agtttatact tttcgctcat ttctttagat gaaaaaccaa attttttata
    23521 aaaattgata taattttcta tattattatt agtaatgacc acatgctcta ttttttttat
    23581 catggcaact ccttaagatt ttatataaat tagttaaatt tatataagtt attaaatttt
    23641 atatagattg ataatattta tataaattac taaattttat ataagctatt gaattttatg
    23701 cagattattg tatttcattt agattataaa acttta
//
LOCUS       DAEQJM010000055        22609 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.055, whole genome shotgun sequence.
ACCESSION   DAEQJM010000055 DAEQJM010000000
VERSION     DAEQJM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22609
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.055"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            449..1510
                     /locus_tag="KRQ43_002706"
     CDS             449..1510
                     /locus_tag="KRQ43_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBH2743052.1"
                     /translation="MRDFLKNYKSSIILLACTIIGVIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKSTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKSLMVAQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQLVIFAVL
                     VGTAIAMMGDRGNTIRKFLSEGTEAILKVVSIVMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAAMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            1523..1720
                     /locus_tag="KRQ43_002707"
     CDS             1523..1720
                     /locus_tag="KRQ43_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBH2743053.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
     gene            complement(1884..2612)
                     /locus_tag="KRQ43_002708"
     CDS             complement(1884..2612)
                     /locus_tag="KRQ43_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH2743054.1"
                     /translation="MKTNYRLHMQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEM
                     LECLGVVDKTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLF
                     GEVFACTRLHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKN
                     ILLHNKIELLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRE
                     LGKMRDEGLLSFNKNKFEIFYFQK"
     gene            2753..3478
                     /locus_tag="KRQ43_002709"
     CDS             2753..3478
                     /locus_tag="KRQ43_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2743055.1"
                     /translation="MMRKIIKIDEGKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            3538..5130
                     /gene="hcp"
                     /locus_tag="KRQ43_002710"
                     /gene_synonym="priS"
     CDS             3538..5130
                     /gene="hcp"
                     /locus_tag="KRQ43_002710"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBH2743056.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKLG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            5494..6399
                     /locus_tag="KRQ43_002711"
     CDS             5494..6399
                     /locus_tag="KRQ43_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH2743057.1"
                     /translation="MKSSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            6523..7476
                     /gene="msrA"
                     /locus_tag="KRQ43_002712"
     CDS             6523..7476
                     /gene="msrA"
                     /locus_tag="KRQ43_002712"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBH2743058.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRIEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEVLGYGEYLKLFE"
     gene            7629..8759
                     /locus_tag="KRQ43_002713"
     CDS             7629..8759
                     /locus_tag="KRQ43_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2743059.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDINISDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(8876..9844)
                     /locus_tag="KRQ43_002714"
     CDS             complement(8876..9844)
                     /locus_tag="KRQ43_002714"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBH2743060.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTKL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPNTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLRECIALSKTL"
     gene            10179..10367
                     /locus_tag="KRQ43_002715"
     CDS             10179..10367
                     /locus_tag="KRQ43_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743061.1"
                     /translation="MNYHTKEELMEVLRVASSRIINCEKVQKKFSEETSHHTRFKNII
                     EAMYISKSLIMDEISKRD"
     gene            10627..11826
                     /locus_tag="KRQ43_002716"
     CDS             10627..11826
                     /locus_tag="KRQ43_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HBH2743062.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKNIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEENKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            11878..12381
                     /locus_tag="KRQ43_002717"
     CDS             11878..12381
                     /locus_tag="KRQ43_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2743063.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            12488..12805
                     /locus_tag="KRQ43_002718"
     CDS             12488..12805
                     /locus_tag="KRQ43_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743064.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            12963..13922
                     /locus_tag="KRQ43_002719"
     CDS             12963..13922
                     /locus_tag="KRQ43_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH2743065.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDIKRFKAII
                     ATSLVLGVLGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            14037..14822
                     /locus_tag="KRQ43_002720"
     CDS             14037..14822
                     /locus_tag="KRQ43_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBH2743066.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDGLEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            15114..16433
                     /locus_tag="KRQ43_002721"
     CDS             15114..16433
                     /locus_tag="KRQ43_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH2743067.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMSIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(16508..16936)
                     /locus_tag="KRQ43_002722"
     CDS             complement(16508..16936)
                     /locus_tag="KRQ43_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743068.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(17027..18403)
                     /gene="hydG"
                     /locus_tag="KRQ43_002723"
     CDS             complement(17027..18403)
                     /gene="hydG"
                     /locus_tag="KRQ43_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HBH2743069.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(18404..19489)
                     /gene="hydE"
                     /locus_tag="KRQ43_002724"
     CDS             complement(18404..19489)
                     /gene="hydE"
                     /locus_tag="KRQ43_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HBH2743070.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSPDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNKDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(19525..20733)
                     /gene="hydF"
                     /locus_tag="KRQ43_002725"
     CDS             complement(19525..20733)
                     /gene="hydF"
                     /locus_tag="KRQ43_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HBH2743071.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVNKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(20748..20999)
                     /locus_tag="KRQ43_002726"
     CDS             complement(20748..20999)
                     /locus_tag="KRQ43_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HBH2743072.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(21380..22420)
                     /locus_tag="KRQ43_002727"
     CDS             complement(21380..22420)
                     /locus_tag="KRQ43_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBH2743073.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT         8508 a         2686 c         3577 g         7838 t
ORIGIN      
        1 ttttaaaagt atatcaaaaa tatcaagtac atgaaaaaat aatatttgac aaaatatcat
       61 atatgtttac aaaattaact tgatggaatg ataaagcata ggaattacaa tgagtatact
      121 aaaactttat attaaagtac aaattattaa atttgaaaat aattaagcaa tattatatat
      181 atttttttat attgtttgtt ttattaaaat taatctagaa aaaaagtttt aaaagcagaa
      241 ttttattaat atttatatat agatatgaac tattaataaa atattaaaga tacaaaaaaa
      301 ctatagaaat tgacatatat tccagtattt gctaaagtag ctgttgggga aaattacaaa
      361 aattattaat gcgcattaga taatttactt taattttttt aggatttagg gtaatttata
      421 atataaaaca ttagaaagga aaatataaat gagggacttt ttaaaaaatt ataagtcatc
      481 aattatactt ttagcatgta ctataatagg ggtgatagta ggattagtac ttggtccaaa
      541 agcttcaata ctaaaaccat ttggagattt attcataaat gctctattaa tgatagtagt
      601 accattagtt tttcttagtg tttcttcagg tgttgctagt ataaaaaata tggaacgttt
      661 tggaaaaata atgaagagta cagctatagt atttatggga acaacacttg taattgcatt
      721 tttaggtatt acatctgcat tattatttaa tccgtctaaa ggattagatg tatcaagtgt
      781 aaaaagttta atggtggctc aagatgcaga aactttagaa tcaaaaggaa cgttattaga
      841 ccaagtagta tcaagtatta cagttaaaaa ttttggagat ttattttcca gtagcaattt
      901 actacaatta gttatatttg cagttttagt tggaacagca atagctatga tgggagatag
      961 gggaaataca ataagaaagt ttttatcaga aggaacggaa gcaatattaa aagtagtaag
     1021 tatagtcatg ctttatgctc ctatagggct aggctgttat acagctacaa taattgggga
     1081 acttggaagc aaaataattc aaggatatgt aagggtgttt gtaatttatt cactaacagc
     1141 agccatgtat ttcttattat tttacagtct gtatgctttt ttatctgcag gaaaacaagg
     1201 gtttagacaa ttctggagaa atgctataaa accaatagca acggcactag ctacttcttc
     1261 aagttcagca tgtataccat caaatttaga agctagtaaa aatataggag ttcctgatga
     1321 tatatcagaa acagttatac ctcttggaat aaatatacat aaagatgggt cagttttagc
     1381 agtaataata aaagtggcat ttttatcagg tattttaggc agtggaatgg caaatccagc
     1441 aacgataggt caattattta taactgtatt tgttgttgga gtatttatgg ctcctgtagc
     1501 aggtggctga cttattggtg agatgctcgt ggttagcatc ttcggttttc cagtggaggc
     1561 aattccattg ttaacagtta taactactat aactgatatt cctaatacta tattaaatac
     1621 aactggaaat acagtatcat caatgttagt ttcaagatta gtagaaggaa aagattggct
     1681 tatagataaa acagcaatta ctacaaagaa aataagctaa ttgtacactt aattaataaa
     1741 gttaataggt atcttaattt taataaatta gatatctatt aactttttaa gtaaaaatat
     1801 aaatttaaga ttcaaatatg atatttataa tttgaattaa ctaatatagt atatattgaa
     1861 ataaatatgt ttaaatatct agtttatttt tgaaagtaaa agatttcaaa tttattttta
     1921 ttaaaagata acaagccttc atctcgcatc ttgccaagct ctcttgacat agaacttctg
     1981 tcaacacata aaaaatcagc catttcattt cttgaaaagg gaattgtaaa ctggtggcta
     2041 cctgtttgtt ctatctgttt tgaaaaatac ataagcaatt tctcgcgagt tgttttacga
     2101 gaaagtaatt ctattttatt gtgaagtaaa atgttttttt cagctattaa ttgtagcata
     2161 ttttcaacaa gcctattatg aaatacacat gcagatgaac aaataccagt tacactttta
     2221 aactttataa ataaaacttc gcaagaagat gttgtggtta ctgtaacatt acttttatgt
     2281 agtctagtac atgcgaatac ctctccaaat aaatctccag gcaagagttc agctacaata
     2341 ttcctattcc cttcgatatc ttcctttatt atatgagcac ttcctttaag cataattcca
     2401 atagaagtaa cttcacttcc aacagagaat attatactat cttttgggta agtcttatct
     2461 acaacaccta aacattccaa catttcttca agctcatcac ttttaattcc ttcaaataga
     2521 ggaatttttt taagtaggtc tatatgcttt tctaaaaatt ttttcaaata atcacttcct
     2581 tgttgcatat gcaaccgata atttgttttc attgtactat actaagttta taaaagcaag
     2641 gggatataaa aatcctacta caagaaattt gaaataaaga aatataggta ttaaaaataa
     2701 atatataaga aatcaatact ttaaattaaa aaaattttat gaggtgatat aaatgatgag
     2761 aaaaataatt aaaattgatg agggaaagtg taatggttgt ggactatgtg ttgaagcttg
     2821 tcatgaagaa gctataggaa tggtaaatgg aaaagcaaaa cttttaagag atgactattg
     2881 tgatgggctg ggagattgtc tgccaacttg tccaacaaat gcgatttcat ttgagtatag
     2941 agaagcagca gaatatgatg aagctgcagt aaaagcaaat atggaagcaa agaaagcaca
     3001 aaagaaaact ttagcatgtg gatgtccagg ttctcagtct aagtcaataa atagagaggt
     3061 ttcaaatagt acatctataa gcaatgatat agtagagata aaaggttctc aacttaatca
     3121 atggccagta caaataaaat tagtaccaac taatgcatca tatttaaaga atgcaagtct
     3181 tttaatagca gcagactgta cagcgtatgc atatggaaat tttcataata aatttatgaa
     3241 aaataaggtt acattaatcg gatgccctaa acttgatgaa gttgactatg ctgaaaaact
     3301 gacagagatt ttaaaagaaa atgatattaa aaatatagta gtaacacgta tggaagttcc
     3361 ttgctgtggt ggtatagtaa atgctgttaa gacagctcta caaaatagtg gaaaaatgat
     3421 accatggcaa atagttacta tatctgtaga tggaaaaatt gtagatggag aaatttaatt
     3481 aagtgaatca tagaaaaata taataaattt taataaataa aaagggagga ataaaaaatg
     3541 gaaaaaatgt tttgttttca atgtgaacaa acagcaggag gtaaaggttg tactataaat
     3601 ggtgtttgtg gtaaaaaggg gggtacagct aacttgcaag acgagcttac aggagtgttg
     3661 attggtcttt caagagcaac tattggaaat aagaatagac caacaagtga aacagataaa
     3721 attatgatag aggggctatt cactactata acgaatgtaa gttttgatga tgaagctata
     3781 aaaagacaaa ttgaaaaaac tgaggtagaa aaaagtaaac ttgtacctag atgttcagat
     3841 tgttcaacaa cttgtaatag aaatgataac tatgatatga aggatttatg gaatgataat
     3901 gaggatatac gttcattaaa atcattaatc ttatttggat taagaggcat ggctgcctat
     3961 gcatatcatg caatggtact tggttataca gacaaagacg taaatgaatt tttctatgaa
     4021 ggattaatag cagttggagg agacttgtct attgacgaac ttttaggtct agttatgaaa
     4081 actggagaaa taaacttaaa atgtatggaa ttgcttgata gagcaaatac tgaaacttat
     4141 ggaacaccag aaccgactca ggtatctatg aaaatcgaga aagggccatt tattgtagtt
     4201 acaggacatg acctttatga tttacacaaa ttattagaac aaacgaaaga taagggtata
     4261 aatatatata ctcatggtga gttattacca gcacatgcat atccaaaact aaaagaatat
     4321 aaacatctaa aaggtaattt tggtacagca tggcaaaacc aacaaaaaga atttgataat
     4381 attcctgctc caatattatt tacaacaaac tgtttaatgc ctgttaaaga tagttataga
     4441 gatagagtat ttactacaga agtagttgct tatccaggta tggttcatat tgatgaagat
     4501 aaagattttt ctagtgtaat agaaaaagct cttgaacttg gaggatatag agaagatgtt
     4561 catatgactg gtattaatgg aggagataca ttaactactg gttttgcaag aggtacagtt
     4621 tcatctgtac aagataaagt agtagatgct gtaaagagtg gagctataag acacttttta
     4681 ttggttggag gttgtgatgg tgcaaaactt ggaagaaatt attacactga atttgtaaaa
     4741 caagctccta aagatactgt tatattgaca cttgcatgtg gaaaatatag atttaatgat
     4801 ttagaccttg gggatatagg tggcttacct cgtttaatgg atatgggaca atgtaatgat
     4861 gcttatagtg caattaaagt ggcagtttca ttggcaaatg cttttgaatg tggagtaaat
     4921 gatttgcctc ttagcatggt actgtcatgg tatgagcaga aagctgtttg tatacttctt
     4981 acactacttc atttaggtat caaaaatatc tatatagggc cttctttgcc agcattctta
     5041 tctaagaatg tattagatat attggttgat aaatttgcat tgacacctat atctactcct
     5101 gaagaagata tgaagaagat tttaggataa ataaatatat ctatacttaa agatatttat
     5161 agttaaaata tttttaagta tgtcacaatt aagataaggg gttaaactta aaatttgatt
     5221 aaaaaatcaa ttttgagacg accctttatt tattttttgt aataattgaa aaataaacct
     5281 gctttcagta tattctttta agaatttttg tattaaattt ataatactta gatatataat
     5341 atcttatata ttttatttta agtactaaag gtttgaatgt aacttaaata ttaaaagagg
     5401 aacattgtaa tatgtaactt gcataaaata tatatactat agtgaaatta ttttgattaa
     5461 aatataaggt gttttatgtg ggggtatatg tatatgaaaa gttctaattt taatatattg
     5521 gcatttgatg gtggtggatt aaaaggggca ttgagtatat ccatacttga gaggatagta
     5581 aaagagtatc caaatctatt aaacaatata aatatgtttg gagggacatc tacagggagt
     5641 ctaattgcac taggacttgc gtatggtgta agccctaaag agataaaaga actttactca
     5701 attgaaaatt ctaagtatat ttttaataaa agttatgcag aaatactcag accaaagtat
     5761 gaaaacaaaa acttaaaaga agttttatta agtatatttc cagaggaact agaattaaaa
     5821 gatttaaata aattagtaat gataccaagt ttttatatag gaaatgagga aaatgcatgg
     5881 aaaccagtgt tttataacaa tatgccaaat tcttttacaa agactagcaa agttgtagat
     5941 gtagcaatgg caagtagtgc tgctccagta ttttttccaa catataatcg tcatgttgat
     6001 ggaggaataa tagcaactga cccaagttta gcgtgtataa ttcatgccat tgacagtgga
     6061 tttaaactta agaatacaag acttttttca atagggactg gatatgtata taatagtata
     6121 aaggcagata ctactgaatg gggagctatt gactggataa ttaataaaga acccgattta
     6181 ccaattatat ctattacctt agaaggaaat tctcaaatga gtcagttatt ttctcaaaaa
     6241 cttcttggag ataattacta tagattaaat cctaagatgg aaaaagatgt agctatggat
     6301 gattgtgatg cattagaata tctaatgtct ttaggagaaa attgtgatat aaaagatgct
     6361 tttggatgga taaagaaaaa gagcttttat agaaattaga ttcaatttgc aattgtattt
     6421 ttgcacatga tttcattgag taggtaaaaa taataaaatg cagattatta agttacttct
     6481 tagggaataa ataaagtata atttatttaa ggagtgatga aaatgataaa acttgctact
     6541 tttgcaggtg gatgtttttg gtgtatggta aaacctttcg ataagtatga tggagttatt
     6601 aaagtagttt ctggatatac aggtggtcat gttgaaaacc ctacatatca agaggtatgt
     6661 tcaggaacta ctggtcattt agaagcaatt caaataacat atgatgatga tataataagt
     6721 tatgatgaac ttctaaatat cttctggaaa cagattaatc ctacagatga tggtggacaa
     6781 tttggtgata ggggaactca atataagact gctatatttt atcatgatga agaacaaaaa
     6841 aatatagctt tagagtcaag agaacatctg gaaaatagta aaatatttga tagtaaaata
     6901 gtgactgata taattccagc aactaaattc tacgaagcag aagaaaatca tcaggattat
     6961 tataaaaaaa gaccattaaa ctacaatatg tattataaag ggtctggaag atataatttt
     7021 gtaaaaagtc attgggatgg aaacaatata aatagggaag agttaaaaaa gactttaact
     7081 cctatacaat ttgaagtcac tcaaaatgat atgacagaag taccttttga aaatgaatat
     7141 tatgataata acaaagaggg aatttatgtt gatattgtaa gtggagaagt gttattttct
     7201 tcaaaagata aatttgattc tggatgtggg tggccaagtt tttcaaagcc agttatagat
     7261 aaatctatca ttgagagaag tgatttctca caaggtatgt acagaattga agtaagaagt
     7321 gctaaaggaa attctcattt aggtcatgta tttgatgatg gtccaaaaga acttggaggt
     7381 ttaagatatt gtataaattc tgcttctctt aaatttatac caagagaaaa tatggaagtt
     7441 ttaggatatg gagaatattt aaaacttttt gagtaattag gaatatttat tataaactta
     7501 tctaaaaggt gaaaatataa aaaaatattt tcaccttttg tttttttgtc aataatatga
     7561 taaattatta attgtaatct tatttatacc aatagattaa gaatttaatt ttgaaagaga
     7621 gaaaacaaat gaatttaaaa gactttaatg gaaagagatt aaaatcagct agaattttta
     7681 gagcaaagac gatagaacag ttgtctaaag aaactaaaat aaataaaaaa gatttaaaag
     7741 cttttgagga aaataagtat gtaccaaata tagaaaatac attaaaatta tctaatatat
     7801 taaattttcc aaaagagtat ttttataaaa atgaaaatat aaatatcgtt gtagaggata
     7861 gccattttaa ccctcaatct aaactaccta gagtagaaga gatttcttat agagaaaaaa
     7921 taattataat acataaaata tattcattta tggagaatta tattaagttt ccaaaagaaa
     7981 acttgccaaa tagaaaagta atgtcagata ttaatataag tgatatagaa tctcttgcat
     8041 ataagactag agagttttgg gatttaaata gtactccaat agtaaatatg gtaagtttgt
     8101 tagaatctaa agggattata atatcaggta tgaatgtaga tagaaaaggg gcaactatct
     8161 ttactcaaaa acagagaatt agtaaagaat ctaaatatct aatatctctg ggtaatgaca
     8221 aaaagtcagc atcaattaga aattatactt tggcatgtga gcttggatat ataatatcaa
     8281 gtgaattaag aataccaagt aagcaatttt cagaagatga gtatgcctgt gcatttttat
     8341 tgccaaaaga gagtttttta aaagatttga ctcatccaga agatttagat tattatgtag
     8401 aactaaagaa aaaatggatt gtacctatat ctgctatgat ttttagagca tataatctag
     8461 aaaagataaa ttacaaaaaa tacaattatc ttatgaatga aatggataaa aaaggctggt
     8521 tgatagaaga accactagac aaaatgaaag gttcaagccc aacgtattta aaaagagcag
     8581 ttgaattatt gatagaaaat aaaataatga gtgtaaatag tatagtatca agtttagagg
     8641 aatttggaat aaatctttat ccagaagact tagaattatt gatgggattg aaaaaaggat
     8701 tgttatctca agaggtaaat aaaaaaagta aagttataaa atttgatggt aaaaaatagg
     8761 tttatatttt agtattaaaa ttaaaagcag gtataaatga tttaaacatt aacttagtta
     8821 aaagtctttt caataagtca tttacctgct tttagtgtaa gaaagaatat tgaatctaaa
     8881 gtgtttttga aagtgcaata cattctctta aaacagagca agatttatta aattcgtttt
     8941 gctcatattc agtcatattg atttcaataa tttcttcaat accatctttt cctataacac
     9001 atggaacacc tgcaaataca tttctttcgt tatattgacc ttctagtaat gtagaaactg
     9061 gaagaacttt tttctcattg tgtagtatag cttttacaat ttctactaaa gcagtaccta
     9121 taccaaattc tgtacaatct ttaccattta ttatacttat ccctgttttt ttattttttt
     9181 caactattga tggtaagtct aaattgctat aagtatttgg gttgtctttt atcatgtcca
     9241 agattggttt accaccaatt gaaacatgag accaaggaac catttgagaa tctccatgtt
     9301 cacccataga ataagcttga attgattgtt gagcgattcc agtttcttca gataaaatcc
     9361 ttctaagttt tgttgaatct aaagctgttc cagttccaat gactttattt ttaggaaagc
     9421 cagatttttc ccaaatataa tttgtaacta catcaacagg attagatatg actacaaata
     9481 taccatcaaa gccagaatca actatgggtt ttactataga ttttatcatt ccaatagttg
     9541 gtcttagtaa atctaatcta gttgtgtttt gtctacgtaa aggcccttct gaagagtctg
     9601 caacacttat cactactatg tcagaatctt tacagtcaga aaaagttcct ttttctatat
     9661 gtactttatg tggtagatat gaaactgcat cagctaaatc taaagcttga gcttttgatt
     9721 tagattcatc tatatcaatc ataaagagtt catcacaaac tccttgagtt attaaactaa
     9781 atccacaatg agaaccaaca tgccctgaac ctacaataga tatttttctt ggctttattg
     9841 ccattttaaa tcactccccc taaaataacg atacattgaa aattatagat gttatcaaaa
     9901 gctgtttttg gatattttaa tattttatta tttcagaaaa tttatttaat atgattttat
     9961 actaaaattt ttaaaaaagc aatgttaata tactctctat taatgaatgt taaagtatta
    10021 tatgtatatt aataattatt aaaatatgta atgtcactga tagttagaat atttaagtgt
    10081 taaaagatat atataaataa taatgatatc agttgataat gatattaaat tgaggtatac
    10141 tgtttctcta aattaaaaaa caaaggagta aatgtgttat gaattatcat acaaaagaag
    10201 agttgatgga agtactgaga gtagcatctt caaggattat taattgtgaa aaagtacaga
    10261 agaaattttc tgaggagaca tctcatcata cacgttttaa gaatattata gaagcaatgt
    10321 atatttcaaa atcattaata atggatgaaa ttagtaaaag agattgaagc ttattttgca
    10381 atttaatatg ttttaatata cattttatta tataagaaaa taagtaagca tacttgttat
    10441 aaaatattga aataatataa aattataaat ttgttaacac taatatctat atgttaaaat
    10501 atagtagaag atgttagtaa ataataggat gagttctatt ttaatacaat taaattaagc
    10561 ttagcttgaa atttgtattt aaaaagtaaa gtagtctata attaagaaaa tggagataga
    10621 attataatgg aaaagttata ttatacaaat cagtatataa gagattttac agcagaaata
    10681 attgaaataa aagaagtaga aaataagtat catgttttat tagataagac agcttttttt
    10741 cctggtggag gaggtcagtt tggagacctg ggaaaaatag agaatgatga tgtaataaat
    10801 gtgtatgaag atggaaaaaa tatataccat gtattagata aaaaacctat aaagatacat
    10861 aaggtaaagt gtagtattga ttgggataga agagaagatg gaatgcatca acattttgga
    10921 caacatgtat tatctggatg tttttttaaa acttttaatg caaatacgac aggttttcat
    10981 ttaggaaatg agtatagtac agtagatata gaaggtaatt tagaagagaa caaaattaga
    11041 gagatagagt tgtttgccaa tgaaattatt cgccaaaata tacaagtaga gacattactt
    11101 ccaacgaaaa aagaactaaa aaagatttgg ttaagacgtg atttgccaaa tactgatgaa
    11161 gagataagag taataaaaat aggtgattta gatacgaatg catgttgtgg agtgcatcca
    11221 aaatcaactg gtgaattgag aatgataaaa ataaagaaat gggaaaaaca taagtcaagt
    11281 acaagaatag agtttctagc aggtaaaagg gcagtggatg aagtattgaa gagggatata
    11341 tatttgacta aaatatgtag atatttaagc tgtagtgagg aagatgctat aaatggtatt
    11401 gtaaatctaa atagtaaagt ggaagaggct ttaattaaaa aaagaaggct tgaagaagta
    11461 gtatctacat atcaggtcaa agaaatgatt gaaaaagcaa ataaggttgg caatatttcg
    11521 gtcattaaaa aaatttatga tgatgaagat ttgaaatatg taaataagat agcaaataaa
    11581 attgcagaat atgaaaatag tattgcatta ttagctgtta aatttaatga taaaataaat
    11641 ttagtttttg catgttctaa aaatttaaaa gatattaata tgggagtttt attaaaggat
    11701 gcaataagtc ttatagatgg caagggtggt ggaagtaaag tattagctca aggaggaggt
    11761 aagaataatg gaaatttaga ggctacactt gattatgcat ttatgaagat agaaaaaact
    11821 ctataaatat attatataaa aaaccttagt agataaaata gatatggagg aataagtatg
    11881 gagcaacaaa aggactacat agagttatat gaaaatgaag aactaataga gataagagaa
    11941 gcacgtatgg atgatttgga tacaatagca aaatttaatt ataatttggc taaagaaact
    12001 gaaggaaaag aacttgatat ggatgtttta actaaaggtg taaaagcatt gttattagat
    12061 gagagaaaag gaaaatatca tgtatataca gtatttgata aagttgttgc acagattatg
    12121 tatacatatg agtggagtga ttggagaaat ggaaatttcc tttggattca gagtgtatat
    12181 gtagataagg aatatagaag aaaaggtatc tttaattatt tatttaatta tataaaaaat
    12241 atatgtgata aagatgaaaa tatagttgga atgagattat atgtagaaaa agaaaacata
    12301 aatgcaaaag caacatatga gtctttaaat atgtatgagt gtgattataa tatgtatgaa
    12361 tacgaagtaa tacattcgta atataaattt gtaatactgt tatactgatg ttataaagta
    12421 ttgattatat tgacgattat atgaaataaa ctggatatta taattagaat ttttaggggg
    12481 tataaaaatg ggcgttttaa aaggaatgtt ttatgtattt ttatttttag atttagtgtc
    12541 aatattctgt ttctttttca ataaaggaaa aatagcatct aataaaattg tgtttaatgc
    12601 aataggagta cttacatttg tactttgttt tatgcttttt agttattatc ctaataataa
    12661 tcttattgga aaatttattg cttctctatt ttttatattt ggagttgcag gagttatgtt
    12721 gaaagaaaaa aattttttat atgctagact tcttttaact gtagttatag ttttttctac
    12781 attaagattg ttcgttattc aataaaatgt atttgtatga aaatttatta aagtctacac
    12841 atttaagtgt aggctttttt gattttttgt ttgaaaatta aggaaatttt aaggaaattt
    12901 taaaatcgtc ttaaatattt attgatatac ttaaaatatt aatagcgaaa ggagacttat
    12961 cagtgataga aagtaaaaag tcagaaaaat tgttactgtc aattatatac ataatatttt
    13021 tggtatatat tttaatgatt ataagaataa ttttatttag agatgtacca atttacgcta
    13081 ttttcaaggg aacgtttagg aatgtaaatt taattccatt ttatacaata tatcaattta
    13141 tagtagatag taatcttgac tttatgaaag ctactgtaaa tattatagaa aatataggta
    13201 tatttattcc tatgggaatt tttttaccta tagtatgtaa aaatctaaat aaaaaaacta
    13261 taattatagt aattatactt gttagcctag catttgaatt aacacaatat atttttgctc
    13321 ttggaagtag tgatatagat gatgttattt taaattcatt aggtggaata attggaatta
    13381 atatttacat aaacatgaat aaattatttc ctaatgatat taaaagattt aaggctataa
    13441 tagctactag tttagtttta ggagttttag gattaggagt tatttctaaa aattatcata
    13501 acttactaac ttttaaattt agacctgata gaaaaatatc aaaaatatta attgaagaaa
    13561 atagggaaat aattaaagat ataaataaag atacagtaga tatagttggg acatttgaga
    13621 gctttaaaaa aggaataata actattaaag caggttctaa taacaaagta aagagaccag
    13681 agaatttaat tgattctgat ggaaatataa gaatttattt aaatgaaaat acaaaattag
    13741 tatcttatat aattaccaaa gaatcaaaaa tggatatagt taaatatgag gaatttgatg
    13801 tgaagaattt agatttatta aggagatatg atactattaa tgtttggatt gataaagaaa
    13861 atcagccaaa ggataaacat ggtattatgg ctagtaaatt attaattgga ttgtatgaat
    13921 aaaatattaa acaagaataa aagaataaca aatataaaaa acgaaaaaac tatttctata
    13981 attattttta cgttgtgcat aaaataagaa cattagtgaa ggagtagaga taaattatgg
    14041 agataataaa atatatcttg tactttttta tatattcatt tttaggatgg acagtagaaa
    14101 gtataggatg ttctatagca agcaaaagaa taatcaacag aggtttttta aatggtccaa
    14161 tatgccctgt ttatggtttt ggagcagtaa ttgtgatatc actattagga agatttaata
    14221 atgtagtaat agtatttcta ttaggaatga ttttaactac gatactagaa tattttacag
    14281 gatttatttt agaaacctta tttcatgcta aatggtggga ttattctgac agaaaattca
    14341 atataaaggg tagagtatgt ttaaaaaatg caatatactt tggtgtaatg tctgttttaa
    14401 taataagatt tatacatcca tttataaaat attttgtaag tataattcca tatagaatat
    14461 taatttcaat ggctataatt acaacacttt ggactatact tgatttgatt gttactatta
    14521 taacacttaa aaaattagat ataaagttaa acttactaga cgatataatt acagacctta
    14581 atgatataaa tgtgaaattg gataaatttg atagaggaga aatacaagct ttatttaaaa
    14641 caataaataa cgacggatta gaagttagag aaaaaataaa caaaataaat agtaagttgg
    14701 accgtataga gtctaatatt attttacaaa aaagagttat aaaagcattt ccacatataa
    14761 aacataaaaa acaacaagag caactagaac attttaaaaa aattattaat gagaaaaggt
    14821 aattatacaa tttaatgaag acgaatagaa taatggtatt tataagatta ttttcagagg
    14881 actctataaa aatagaatag agtcctttat tttttgaaaa ataatgttta tttgataaaa
    14941 ataaaatata ttgtttctaa ataacaaata ttttgaaaat tataaaaaca tatattgaca
    15001 atttgtgtca aaaatactaa cattaagtat ataaagaatt ttatatgaga atatctttat
    15061 aaatcgcaat aattttagaa cataaattta tttaaagagg ggatgatttg ccaatgagcg
    15121 agataactag tcaaatgata agtacagaag aaaaaaaata tgttgctaaa actcaaaaga
    15181 taccttatta tccagtagca tttaaatcag gtgatggtgc aatgctatat gattatgaag
    15241 gtaatgaata tgtagatttt ttagcaagtg caggctctgc aaatgtaggt catggtaata
    15301 aggaaatctc acaagcagtt aaagaacaaa tggatgatat aacacaatat acacttgcat
    15361 atttccatag tgatcctcct gtaaaattag ctgagaagct tgtggaaata gcccctggag
    15421 ataatgataa aaaagtacta tacagtgcaa ctggttctgc ttgtatagat gctgctataa
    15481 aattagcaag agggtatact ggaagaacaa agataatatc tatgtgtgaa tcttatcatg
    15541 gaagtactta tggagctata tctatatctg ctttaagtac aaatatgaga agaaaaatgg
    15601 gtccattgtt accagaagtt tatcacttcc attatcctga taaaaataga acagctaaag
    15661 aatgtttaga tgagatagaa tatgcttttg cacactatct accagcagaa gaggtagctg
    15721 caatatttat agagccaatt gcaggagatg caggaataat agtgcctcca gtagagtggg
    15781 tacaaggttt aagtaaaata tgtaaagaaa atggaatatt acttgtaagt gatgaaatac
    15841 aacaaggtat gggaagaaca ggtaagtggt ttggtataga aaattttggt gttgaagcag
    15901 accttatagt tcttggaaaa tctgttggag gtggattacc tttaggagca gttgttggaa
    15961 gaacagaaat aatgcaaagt cttgatgcac cagcacattt atttacttta gctggaaata
    16021 caacagtgtg tgtcgctgct ttaaaatcta tagagataat tgaaaaagaa aacttacttc
    16081 aaaagagtat agaaatggga gattatatta aagcaggatt tgaaaaacta aaagaaaaat
    16141 acgatataat tggagaaata agaggaatag ggttatctat aggagttgat atagttaaag
    16201 gaaaaggttc taatgaaaaa catccagatg ctacagctaa gatatgttat agatgtatac
    16261 aaactggatt aataatgata ttcttaggac aatctacttt aagagtacaa ccacctctag
    16321 taataactaa ggagcaagta gataaagcaa tgagcatcat agattctgca atagatgatt
    16381 atttaaatgg tagaattggt gatgaagtat atgaagtaac tcaaggttgg taaaataaat
    16441 attaaatgaa aaaaagagtt atctcaattt tagaaagtaa tttctgaaat gagataactc
    16501 ttttaagtta cccacaaata agaaaattgt ttgattcatt aaagactata tttcggatgt
    16561 cgtttttgtg agtatcagag acagtattac gagaataatt acctttattc gtactatctg
    16621 ttaatttagt tataattaag atagctaaaa gaataagaat tactgtgtat aaagcaataa
    16681 catatggttt tcttttatat ttgtatttgt tattgaaaaa agaatggcca taattatttt
    16741 tatttacttt agatgtattt gtattctttt tcttgttacc tttcttttta tcatcctttt
    16801 ttctattttt agggtaagga atgactttgt gtgtattatc aagtttgata tttttatttt
    16861 tttgaatatt gttttccagg ctagcctttt tttctccaaa ttgaatagtt ttattggtat
    16921 tgttgttatc tttcaatgtt aatctccctc ccttaaactt tccctttaga taatattact
    16981 actaacctat ggaatataca ataaataata tataagtaat aaaattttat aggtataaat
    17041 ctctttctcc acgctctaag gcagtcatat tgttagatac tatgtttctt atatcttctc
    17101 tttctatctt acctatttct tctgcgataa gttttttacc cataatttta agttcttcat
    17161 ctccataatc gattaaaaat tcatttaatg tagtaagagc atttggcgta catacattat
    17221 ggatttgtcg acttttagct aagctcatga atctatcgcc agttctacct ttacgataac
    17281 aagctgtaca ataactaggt atatatccat cagtaatcag ttctttaagc acctcaacag
    17341 ggcttctatg gtctccaact tcgaattgtt ctgtattgtc accatcttca tatgctttat
    17401 atcctccaac acctgttaga gaacctgcac taatttgtga tacaccatat tttagtaact
    17461 catttctcat ttcagcagtt tctctagtgg acattatgat tccagtaaaa ggaacagcca
    17521 atctagttat agctactatt tttttgaaca tatcgtcaga aactaagtga ggaaaatctt
    17581 ctaagctcat accttcagct tttttcaatc tagggaaaga tatagtatgg aaacctacac
    17641 caaatttttc ctctaagtgt tcgttgtgca tcataagtcc tagaacttca aatttagggt
    17701 cagataaacc aaataaaact cctgcaccaa catcatcaac accagcttcc atagctctat
    17761 caaaagctgt taaatggtaa taatagtcat tttttataga ttgaccatgc atttttataa
    17821 atgttggttt gtgataagtt tcttggaata atatataagt tcctattcct ttttctttta
    17881 gtaatttata ctcatctaca cttgtagctg ctatgttaac gtttaccctt cttatatttc
    17941 cgttttcatt atatgttgaa taaattgcat ctaagcaatc taagatgtaa tttatatcac
    18001 aatttttagg gtcttcacca gcttctagag caagtctttt atgacccatt ttttctaata
    18061 ttttaacctc ttcctttatc tcttccatgg taagtttttt tcttttaaat ttgttgcatt
    18121 tactaaaacc gcaataaaca cattcattta cacagtagtt tgatacataa agaggggcaa
    18181 ataaaaccac tctattacca tatatttcat tttttatttg cccagctata ctaaataatc
    18241 tatctagttg ttttttatct tctacttcaa gaagtgtagc tatatcttta taactaagtt
    18301 tttcccttct atcagcctta tcaagtacct tttcaatatc atcagaagtt gaattttttg
    18361 catcttctaa taaagaatta ataagttcat ggtttatgaa catttacaaa cgcctccatt
    18421 caatattatc accgcgagaa tagtcaactt caagtcctaa tgacttgatg ttttcttcta
    18481 aactttggtg atattcacaa gcttcttgac cagtaaaggc tttgttatcg taaagagaat
    18541 attgttttct aaattcttga ggagaaaggt ttggcataat tacattgcaa ccagctaaaa
    18601 gacctgcatt tctaccacta gggtttatag atgccaaggc tgttgtagcg ggtaataaaa
    18661 cttttggaag tagaagtctt gtaattgaaa gcataagtaa tgtcttctct aaatctccat
    18721 gtttataatc cttaaaaatt gtatcatggt gtggaataaa aggtcctatt ccaaccatat
    18781 gaggatttaa ctcttttagg tataataaat cacgaacaag gtctttgttg ttctgaaatg
    18841 gtgattcaac cataaatcca gcacctacct gataaccaat ttctttaagg ttttttaggc
    18901 attcttttct agttctaagc tcaatgtttg gcggatgtaa ttttttataa tgactgtctg
    18961 tagcagtttc atgtcttaaa agatatctat ctgcaccaca taaaaagtat tttttatacg
    19021 aatcataact cttttctcct agtgacagag ttatggcaca atcctcatat ttatttttta
    19081 tacttgaaac aatttcacat attttatcat cagtaaaata tgcatcttca ccaccttgca
    19141 aaacgaatgt tctgtatcct attttataac ctatatcaca acattcaagt atttcatcag
    19201 gtgaaagtct gtatcttatg atatttttat tagaagattg tattccacaa tagtagcaat
    19261 tatttttaca atagtttgta agctctataa gtcctctcaa gtagactcta tttccataat
    19321 gtttatttct catgtcgcta gcttgtttat aaagatagtt tcttaaattt tgttcgaagt
    19381 tatattcctc attgtcgata ttttctatta aatatagtag ttcatcaaaa cttaatgaat
    19441 taatgctgta aagtttatct ataaagtatt taatcttatt tttagtcata ttcaaatatg
    19501 taattattaa gtatagttaa atttttaata attgaaaagt tcaagtgatc tttccaaaat
    19561 accttttaca tatgctatta agataccata gtttacaata ggtacattga aagattttgc
    19621 cttttctatt ctagataaca ttccagctct attcatcata caagctccac agtgaactac
    19681 aagggcatat ttatttatat cttcagtgaa ggatactcca gaactaaatt caaaagtaat
    19741 atttttgcca gttttctttc taatcatatt aggaattttt actgttccaa tatcatcagt
    19801 ttgtctatga tgggtacatc cttcagccat caagatttta tcaccatctt ttaaattttc
    19861 taaagcataa gctccattaa tcaattcttt aaggtctccc ttttgtctag caaacaatat
    19921 agaaaaagat gtaagaggaa tatcttttgg tgtatcttta tttacttgtg gaaatacttg
    19981 agagtcagta ataacaagtt ttggtttttt gcctaaatta gatagagttt cttttaaact
    20041 atcttctttt gtaactatag aaattgcacc attatccaaa atatctctta taacttgctg
    20101 ttgaggaagt ataagtctac cttttggagc tgctttatct attggaacaa ctaaaacaac
    20161 taaatcattt ggttcaatta aatctgatac caatttgaac tcagtgctat ccttaggcaa
    20221 aacttttatt atttcatttt ttaaattttc aattccaatt ttatctgttg atgagacaga
    20281 aacaactgga catttaactt tatttttagt taagtttaaa atttctgatt gattcttaat
    20341 agtatcaatt ttgttgagaa ttagaatatg agggatattc ttatcattaa acttttcaat
    20401 tagtgacaaa tcttcttgtg atataccaat ttggcaatcc actactagta aagctatatc
    20461 tgtcttttct aaaacatcta gtgatttacc tattctaagt tcaccaagtt caccaacatc
    20521 atcaagacca gcagtatcta taagaacaca aggtcctata ggaaggattt ccattggtct
    20581 aaatactggg tctgtagtag ttccagcaat atctgagact attgcagcac tttgatttgt
    20641 tatagcattt attatgctag atttacctgc atttctttta ccaaagagac ctatatgtac
    20701 tcttaccgat tgtggagtag aatttagact catttgtact caccacctta aacttctttt
    20761 tttgatatac tagtttttac agatacatga ggtatgttgc ccaatttacc agtcaaacta
    20821 ttaatagtat ccatttcgcc aacaactgct atacatacga ttgagacacc ttcttcttcg
    20881 caaggaatgc ccattcttcc tttaataata cctttaaaac ctgatacaac ctcattgaat
    20941 ttaaattgac attcttttgg ctcttccaaa atagcactta taactgcaac ctttttcata
    21001 aatatcctcc taactcagaa aatatgtctt aaacaaatcc aaaatcaaaa aacttttctt
    21061 tgtaaagaaa agtttctaca aaagaaaagt tattaattac acaagtataa tgtgctatat
    21121 taaactattt ccttacagat tagataactc ttttctggta gggttagctt gtaaaaattt
    21181 aatttaacaa caagtaactg aagaaaattt ttatacaatt tatataaatt ataataaaaa
    21241 ttaactaaag aaaattgaag ttacttatat aatagtagta aattgaaatt aagtctatag
    21301 aaaaaccaat ttttgtataa aaataaaaat taaagttaat tatttgttaa gaattgactt
    21361 tggtaaaata tataattaat tattctttaa gcatataatt tataagtaat tttagtgtat
    21421 tttcaatagc ttctatatgt gttctttcat aatggtgact attgtttgtt ccaggaccaa
    21481 cacatgctat ttgaacatct tctccccaac gaatagcttc tgaagcatct gaaccataga
    21541 aagtaaatac atcgacagcg tagtctaaat tattgtcttc tgcaacatcg acaagcttgt
    21601 ttcttaaatt aaaatcatat aatgataaat tatcttttgc aactatagtt acaccatgtt
    21661 cactagatgt ttgacttggt ccagtaggtg ctatatctat tgctacaaat tcttttgttt
    21721 tttcaggtaa acatttagaa acaccatgtc caatttcttc ataattactt atataaaagt
    21781 tagtagtatg cttaggcgtt aaattgtttt ctttaaaata tctacatatt tcaagaacca
    21841 ttgctacagc tgatttatta tctatatatc tagattttat aaaaccagat tctgtagcct
    21901 caaatctatg gtctaggcat acaaaatccc caacacttat tcctaaatct aatacatctt
    21961 gctttgtaaa tactttttca tcaagtctaa taatcattgt ttcttcattt ctttcagtgg
    22021 cagcttttgt ttgaccatat atatgagtag aagcatactt aaatacaaca cttcctctga
    22081 tttttttacc ttttctagtt ataacagtgc agttttctcc ctctatagct gcccaacatc
    22141 caccaccaac tttatggtat ttaagagtac catcagatga tatttctttt actatagctc
    22201 caagtgtatc catatgtgca gatattgtta tttgatttga atcatcttca ccaggaagag
    22261 tagctataag tgcacctttt tttgtaagaa tagtgtcaag acctaaattt tcaaaatctt
    22321 ttttgatttc taaaactgca ttttcagtat atccagctgg gcttggaatg tccaaatatt
    22381 ttttcattaa atttatagta ttagttaaat ttaaattcat attgtttcct cctaaataaa
    22441 tatatttata caaattataa cataaataca aatgttctga aaactaaaat taaaagaata
    22501 gaatctaaac atatttaaaa aaaaagtata taaaataaat ttgatttata ttatatagat
    22561 ttaaagtaaa aatagtttta tttaataatt aataaaaata aatacaaaa
//
LOCUS       DAEQJM010000056        22537 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.056, whole genome shotgun sequence.
ACCESSION   DAEQJM010000056 DAEQJM010000000
VERSION     DAEQJM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22537
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.056"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..904)
                     /locus_tag="KRQ43_002728"
     CDS             complement(<1..904)
                     /locus_tag="KRQ43_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH2743074.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVES"
     gene            complement(944..1291)
                     /locus_tag="KRQ43_002729"
     CDS             complement(944..1291)
                     /locus_tag="KRQ43_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743075.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(1509..2465)
                     /locus_tag="KRQ43_002730"
     CDS             complement(1509..2465)
                     /locus_tag="KRQ43_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBH2743076.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTIYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIQAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            2906..3274
                     /locus_tag="KRQ43_002731"
     CDS             2906..3274
                     /locus_tag="KRQ43_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HBH2743077.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNKVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
     gene            3699..3944
                     /locus_tag="KRQ43_002732"
     CDS             3699..3944
                     /locus_tag="KRQ43_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743078.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
     gene            4043..4306
                     /locus_tag="KRQ43_002733"
     CDS             4043..4306
                     /locus_tag="KRQ43_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HBH2743079.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(4591..5538)
                     /locus_tag="KRQ43_002734"
     CDS             complement(4591..5538)
                     /locus_tag="KRQ43_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBH2743080.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALATEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(5541..7172)
                     /locus_tag="KRQ43_002735"
     CDS             complement(5541..7172)
                     /locus_tag="KRQ43_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH2743081.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            7302..8219
                     /locus_tag="KRQ43_002736"
     CDS             7302..8219
                     /locus_tag="KRQ43_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH2743082.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            complement(8276..8857)
                     /locus_tag="KRQ43_002737"
     CDS             complement(8276..8857)
                     /locus_tag="KRQ43_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH2743083.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(8897..9463)
                     /locus_tag="KRQ43_002738"
     CDS             complement(8897..9463)
                     /locus_tag="KRQ43_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH2743084.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            complement(9918..10778)
                     /locus_tag="KRQ43_002739"
     CDS             complement(9918..10778)
                     /locus_tag="KRQ43_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH2743085.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            10927..11817
                     /locus_tag="KRQ43_002740"
     CDS             10927..11817
                     /locus_tag="KRQ43_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2743086.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLSPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            12035..13789
                     /locus_tag="KRQ43_002741"
     CDS             12035..13789
                     /locus_tag="KRQ43_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HBH2743087.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDVTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNVKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVSVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLVGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            14173..15159
                     /locus_tag="KRQ43_002742"
     CDS             14173..15159
                     /locus_tag="KRQ43_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH2743088.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPMVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            15382..15465
                     /locus_tag="KRQ43_002743"
                     /pseudo
     CDS             15382..15465
                     /locus_tag="KRQ43_002743"
                     /inference="COORDINATES: protein motif:HMM:NF012587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            15496..16977
                     /locus_tag="KRQ43_002744"
     CDS             15496..16977
                     /locus_tag="KRQ43_002744"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBH2743089.1"
                     /translation="MYKEPKYRTILESIKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSVLEIFI
                     NDGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            17003..17974
                     /locus_tag="KRQ43_002745"
     CDS             17003..17974
                     /locus_tag="KRQ43_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBH2743090.1"
                     /translation="MKKVISIGEALIDFIPNQNGCKLKNVSEFRRVAGGAPANVSVVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFMTGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(18230..18832)
                     /locus_tag="KRQ43_002746"
     CDS             complement(18230..18832)
                     /locus_tag="KRQ43_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH2743091.1"
                     /translation="MEICILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEKHSRQFAKQIYYILDNSIEVDNC"
     gene            19113..20324
                     /locus_tag="KRQ43_002747"
     CDS             19113..20324
                     /locus_tag="KRQ43_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HBH2743092.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKYDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIVFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            20392..20589
                     /locus_tag="KRQ43_002748"
     CDS             20392..20589
                     /locus_tag="KRQ43_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HBH2743093.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            20623..21594
                     /locus_tag="KRQ43_002749"
     CDS             20623..21594
                     /locus_tag="KRQ43_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2743094.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            21781..22158
                     /locus_tag="KRQ43_002750"
     CDS             21781..22158
                     /locus_tag="KRQ43_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH2743095.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         8622 a         2771 c         3301 g         7843 t
ORIGIN      
        1 cagattcaac aaaactcttt ttatctccta attttaagat aaaatcagga tattcttcaa
       61 attcattgag ttttattaat ttgaaagaag aagatagatt tttaaagtta atgattttag
      121 agttattcac taatacactt ctttttttaa aataaatttc ttttttactt atatttagta
      181 tagttaatat ttgtttaaga tatattatta tatcttctgg agttctatca aatttgagtt
      241 caaaattttc atcttcaaag tagggaatat aatataaagg tgttttgaga gcaggtaatt
      301 tattatataa ttcttcaaga atatcgatat ttttagggga gttaaagaaa aagcatttac
      361 atacgttcat taaatccaca gcatctgaaa gtgagttatg tttaatatct ccttctacag
      421 aaaaaatttt tttcatattc agtaaagata tttgcttaga taagattcta ttattgtatg
      481 taatatgttg agatataaaa ggttgaatgt caatcatcat attaaataac tctaagcatt
      541 tacctgtata tttatatact ctaaatgaag ttagaaggcc agttatatca aaatcacccc
      601 aattatatat tgtaacatca tcaaatttac aaaaccattt ataaaaatca tccataacat
      661 ataaaagatt aggagcatta ttgatatcta gttggttcaa tttggttaaa tttttacatt
      721 tatttgaaag tattttattg tattttggct taactaaaga gtaataatta tctattgtat
      781 taaattcgtt atcaactaaa actccaccaa tagaaattaa ttccgcacca ttatattctt
      841 ttggtttatt tttattatca tctagtatat taaattcaaa gtctataaat aacttgtatt
      901 tcataaatct aaagcacatc ctcaggtaaa ttatttattg agcctaagca tcataagaat
      961 caatagatat aatgactcta aacatcaaag gttcattaca acttttattt atttcataat
     1021 ttaattcaaa taaatctttt aagatataat ttataagtat tctttcccaa cccattttta
     1081 aattaacttt agagtctatt aatatatttt ctatcttttt aaatatttct atatttgctg
     1141 gtattatact gagctcaata ttacttttaa acgggttaga ctgtaaatct gttataagta
     1201 tattttttaa ttcctctgta agttcagaaa ttaaactatc acctatgtat ttttttatga
     1261 tttcctctct aatttctttt aaatttagca atattagtac ctgctactta catagtagct
     1321 tttcctttcc ttttaatact attattcatt tttgaatctt atttagatat attttaagat
     1381 taaaagtctt tagctatata attttttacc catttttaac ttatattaac atattacagg
     1441 cttatatctc caccctgctt acattgagga tggagtatat tgcctatttt gataaaaatg
     1501 ataggttgtt atttgcctat tcctttttct gataattttt ctaacatatc tttggtcatt
     1561 ttatctaaat cataactaaa cttaaagttc cattctttta ctgcactact actgtctaga
     1621 gagttaggcc aagaatcagc tatactttgt cttacagggt ctacatcata ttctatcaca
     1681 aaatcaggaa tatatttttt tatagaatca gctatttctt caggagaaaa gctcatagca
     1741 gtaatattaa aagcatttct atggatgagt ttatccgctg gagcttggat taaatccact
     1801 attgattgaa gtgcatcagg catatacatc atatccattt ttgtaccttc tgctatgtaa
     1861 gatttatatc tcttattttt taatgcctca taatatatat caactgcata atctgtagtt
     1921 cctccaccag gaggcgtaac ataagaaata agacctggaa atctaacacc tctagtgtct
     1981 actccaaatt ttgagtgata ataatcacat agtaattctc cagaaacttt agtcacacca
     2041 tatatagtat taggtctttg taatgtatct tgaggagtca tattttttgg agaattttca
     2101 ccaaaagcag caattgaact aggtgtaaaa aatttacaat ccaattcttt ggctatttca
     2161 aggccattta ttaatccatt catatttaag ttccaagctt ctaggggttt actttcagca
     2221 actgcagaaa gtaaagatgc tagatgaatt atagtatcta catcatattt ttttgcaatt
     2281 tcaaaaaaac gattcttatc tgtaacatct aatatctcaa atataccaga ttcacatact
     2341 ggattacctt cttttactct ccttgaacta gcgattacat tttgttctcc atactcattt
     2401 ctaagcttta ttgttaattc tgaacctatt tgtcctaatg cacctgttat aagtattttt
     2461 ttcaatttta caacctccta agggtttaat ttatgtagta ctacttattt ttattttagc
     2521 aaatcttttg tttaaataca aagaattaaa gataataata tacgacttaa ttgaatgaag
     2581 tgcagtaaat tcctaaaaat ttaaagttga gatataatgg tctattgtat aacaataaaa
     2641 gactagatta aattattata tagattgtgt gactaagtca cagaaagtat agttaattta
     2701 atatataata aaagcatatc aagtaaagct ttaaattaaa gtaactttat ataaaaagta
     2761 atataaattg ataaaattat aaatttattt atagtgaata taggttggat tttatagata
     2821 caaaaatagt atatatgata tgtagaccat tagcatgttt aaagtagcaa aacatataaa
     2881 ataaaatttg aaaggaagta taaaaatgac aagaccatca atatatcata gccaaggata
     2941 cacttgtgca gaggcattaa taaagtctta taatgaggaa cacaacacag atataccaat
     3001 ctcaatagga agtggtatgg gggttggaat gaatgttgga agtgtttgtg gagctgtaaa
     3061 tgctgctgtt gttataatag ggtatttaaa tgggcgaaat agtaatttag atgaaaatat
     3121 agcaaggaag tattcaagag agctattgaa taaagtaaga aataaataca gctcagaaat
     3181 atgtgtatct cttaaaaaaa ataaagtaac ttgtgaagaa ataataaatt tcacatatga
     3241 tgctctaaat gatatgctaa aaaatcaaaa ataattctaa gaaacaagta ttttacattc
     3301 gatagaatac ttgttttttt atgatatttt taataggtat tagtttatta taatttttaa
     3361 atcaatttta ttatatttta attgaaataa tctactttga aaattactaa ctgacaaaag
     3421 aatatgatta tagtatagaa aaaatgtaaa ttatttaata ttaagtgaga gtatatgctt
     3481 acctatataa aatcgtataa attaatggct aaatttataa attataaaga aatatataag
     3541 aaaacaaaag aattaattag tataatataa agttaaaaag tgaaaattta tataatttat
     3601 ttataaagta aagaaaaaat agaaatttgt aatgaaataa aaagtttatg acataatatg
     3661 gtataattag taaaaatata gagattggag gaattgcttt gtttatagat gaagaattag
     3721 aagggtatat attaacatgt aaaatatctg aagactttaa aaatatacct gaatatagtg
     3781 atgaagagtt ttatgttaca gtctataaag atgaaagttc tgactctggg tactatgctt
     3841 tattagaaaa taaagaagaa agagttgtat gggatggaga agttgttgcc aataatattt
     3901 ttaataacct ttggattgta gtaaataagg ttaaaactgg ataatagtct aattatatag
     3961 tatttgtaat attttaaatg aatttttaca tatttgagat gagtaaataa caaagattat
     4021 tcgatactgg aggagtaatt caatggaata tagttatagt aagatgaact taaaaaaagg
     4081 ggatattgta gaggtaaatt tagagaaaca agccaatgta atattgttag accatataaa
     4141 ttatgtgaaa tttaaaaatc aaagaaatta tgattactat ggtggatttg caaagaaaaa
     4201 tccatgtaga atgagagttc ctaatactgg aacatggtat ctagtagtaa atcaagatgg
     4261 aaatagtgga atagtaaact tttcaatcaa tacaattcaa aattaatttt agaatattgg
     4321 atattcttac tttttgtact ttttatatag ttaaaataaa attaataagc aattattata
     4381 aaataatgtg ggtgcctcaa aatgaatttt ataattcacg agacactctt ttttgtataa
     4441 actcaaatat actttatcat ttcaacaatg aaaaagaggc gtatctgtgt tttgagatag
     4501 cctcatttat catatatcat atatagaatt ttaattattc ttaactaaaa ttttttccat
     4561 aggttatctg tacaattaaa atatttattg ttagcataca gctccacctg taaggtgtaa
     4621 aagagcctct agtatctctt cttttctttc caaaacttca tctgataaaa gcatttctat
     4681 aaatttatca gcaccaattc tatcgatagt tattccaaaa cgttcacctg tgttaccctg
     4741 ttctctaaat aaaagaattg ctttttcaat taaagtcata agttcctctt ttgaaaataa
     4801 tctatcaatc tgtgttccag gacgaactga ttttccccat ttccctccta tatagacttt
     4861 ataaccagat tctttttctt caatactatc aaaattacaa ctttctatac acttaccaca
     4921 gttattacat agattactgt ctatttcaag tttaccttta tctgttaatt tagctgcttt
     4981 aacaggacag acctctacaa cagcacattt tttacaacca acacaaagct ctgaatcata
     5041 gtcaggtaca cgttgaccaa caattccaag atcgtttagg tcaggtttaa tacagttatt
     5101 agggcatcca ccaacaccaa ttttgaactt atgaggtagt tttacatcat accaattttt
     5161 gtaaaattct tcgtgtattt cagtagcaag tgcctgtgta tcagctagac catgaacaca
     5221 aacagtacct ttacaagcca caacaggacg aacccttgat ccagttccac ctgttattag
     5281 attttcgcta gcaataaatt cacttagagc ttcaatatct tcaaatttta caccaggtaa
     5341 ttctactgtt agtctagtag taaatgctaa ctgaccgttt ccgaattttt cagcagcttc
     5401 tgcaattttt tttgcttgtg atgcatttat tacaccattt acagttatta tacgtgctgc
     5461 aaaatgttct ccatccctgc ttggtagaaa acctctacct tttacttcct ttttttgttc
     5521 tgctgtaaca ttactcatat ttactcctcc attaccttaa gatttggata aaatagtatt
     5581 ccaccttcaa gaactttcgt atttgtatag ccaaagcgtc ttaagcgatt ttgcgccata
     5641 tagctatttt tacctttagc acatataaga agaatttttt catccttagc aagaccttca
     5701 atttctccat taatttcacc aacaggaata taacgtaaac taggaataga aggagctttt
     5761 gaaacatcaa gtttagtcca actgtcaaaa tcctcaattt cgtcaagtaa aacactatca
     5821 agttctccgt taagtttatt ttgtaaaaca tttactgcca ctacaaaagg gtgaatagct
     5881 gttgaaaaag gtggtgcata tgcaaggtcc atactttcta atgaataaag gtcagcgcct
     5941 aaagttattg cagtagcagc gatatctact attttatcaa ccgctccagg tcccataact
     6001 tgaacaccta ataattttct agtatttttt tcagcaacca ttcttataat aaaattagat
     6061 gcacctggat aataatgagc tttatcatcg gtagctatgg ttacagagca aacattataa
     6121 ccttcttttt cagctatttc tttacttaga cctgtttttc ctgcattgag ctcaggtaat
     6181 tttactactg tcgttccaag aacaccattg taagttttag attttccaga tatattttgt
     6241 gcgcaaattc taccctcatg atttgcagat gaccccatag gtgaccatgt aggtttattt
     6301 gttaaagaat tttttacaaa agcacagtct ccaactacgt atatatcttt atcatttgta
     6361 agcatatatt catctgcaat aattgtatta ttaggggcaa attctaaacc tgtgtctttt
     6421 agaaaacctg tgttaggacg gattccaact gacataacca ctaaatctgt tttaatagct
     6481 ctatttttag tacgaagttt ttcaacttta ttttcacctt caatacctac aacctggtca
     6541 cctgtaaaaa tcattatgcc tttatcagcc atatgatttt caacgtattc agcaaaatca
     6601 gtatcaaatc caggcataac atgttcagcc atatcaacaa cacttacacg tatacccatt
     6661 gcagaaagat tttcagcaat ttcaagacca atgaaacctc caccaataac aacagctctc
     6721 ttaataccgt tttcaataga atctcttagt tttatagcat catttggagt acgcataaag
     6781 aatactccag gtaaatctat tccaggtatt ggtggtttta ttgggtctgc ccctgtagca
     6841 attacaagtt tgtcatagct tagattttct ttttctcctg ttgaaagcgt tttcaaagtt
     6901 acttgttttg catttctatc aatagacgta acttcaactc cacaacgaac ttctgctcct
     6961 gttagtttag aaaaactttc aggtgtattt acgattaaag atgatttatc ttcaattatc
     7021 ttaccaacgt aatatggaag accacaacct gcataagaaa tatcatcacc tttatttagt
     7081 attgtaacag agcaattatc acccatttca cgttttattt ttgcagcagt ttttgttcca
     7141 gcagcaactc cacctataat taatactttc acaatatatc acactccaat ctactttata
     7201 actctataat aaaattatac ttcttgacaa tatatttgta aaatactaaa atattaataa
     7261 aatcataagc atttactaat gtttgctaag gttgtgataa tatgacaatt cgtagtcttg
     7321 aaatctttgt taaggttgct gaatgtggta aaatgagtga agtagcaaga aatatgtata
     7381 ttacccagtc atcagttagc caagctattt cagaaataga aaaagagtat ggtgttaagt
     7441 tatttgatag aatttcaaaa aaattatatt taactgaggc agggaaaaaa cttcttggat
     7501 atgggaggca tcttttagct gtaaatgaag aaatgaatga ttgtatgaag cattgtgcaa
     7561 aaaatatccg tataagagtt ggggcaacag taactgttgg tacatgtgta ataagcccga
     7621 taatgttaga attatacaag gtaaatcctc ttatagaacc tgaagtattt gtagaagata
     7681 caagactgat tgcaaaaaaa ttacttaata gtgaattaga tattgcgatt gtagaaggaa
     7741 aaattaagca cccagatatt gttacaaaaa gcattattaa tgataatctt gtacttatat
     7801 gttcacacaa gcatgagttc tacaaaagag actctataaa agtttcagaa ctttcaaatc
     7861 aaccattaat tatgcgtgaa ttaggaagtg gtacaagagc acaattagaa aagcaattaa
     7921 aagaattaaa aatcccaatg aatattagat ggtcatgtta taactctgaa gctatattaa
     7981 gagcagttgt agataatttt ggcattgcag ttatatccga attacttatt gaggattatt
     8041 taaaaaagca tcttttgtgg gcttgtgata ttgaaggtat taacttacat agaacattcg
     8101 atattgcata tcatagaagc aagtttttta cagaaaatat ttcagcattt tttgatattt
     8161 cagtagaata tgggaaaaaa caagcgagaa agaagagtag aagtgtaaac agtttataat
     8221 atatctaaat aaaaataaga gtatatcaat atactcttat ttttatttag atatattagc
     8281 ctatattaac gccaaaattt ttacacaatc ctgcaagtcc atcctcaaat ccagaaccta
     8341 aagcattaaa tttccactct ccattatgtc tatatagttc tgccacgact attgctgttt
     8401 ctatgctaaa atcttcaccc aattcatatt taataagttc ctcgttagtt tcttcattat
     8461 atattcttat atatgaattt tcaacttgtc cgaaattttg tcttcttgta attgcttcat
     8521 ttatagtaac actaaatgat attttagcaa tattttgagg tattttagat aagtctacat
     8581 ttatttgttc atcatcacca tcaccaacac ctgttctatt atcacccata tattcaacag
     8641 ctccagaagc gtgttttaaa ttattataga atataaagtc tccatcattc gttacttttc
     8701 catcagttcc agttaaaaat gcagaggcat ctaaatcgaa atcaaatcca ccatcatatt
     8761 tattaatatc ccatcctagt cctactatta ctttttttag accagggtta ctttttgtta
     8821 aacttacttt ttgtcctttt gctaaagtta tacccattta aaccaactcc tcattataaa
     8881 ttttttattg taattattac ttatatgtat taattaattc acgaagctct tcattttgac
     8941 caattcctaa agcattaaat ttccattctt catttctacg ataaatttct cctgccaaaa
     9001 ctgttacttt accagaaaag tcttcttgaa gattatattt aaataattct tgcttggaat
     9061 ttgaatcaat taatcttata aaagagttgt tcatttgacc aaaatcttgg tctctttttt
     9121 tagctttgta tatagaaact ccaaaaacta ttttatgtac atattcaggt atgtcttcta
     9181 aattaacaat tatttgttca tcatcacctt caccttttcc agttaagtta tctccagtgt
     9241 gtataatagc tttagaaggg tgtttaagat ttccaaaata aaccaagtca cctctaacat
     9301 tcattttatc ttggttagtc aatgctattg caaatgcatc taggtcataa ttttttttac
     9361 ccaatttatt catatcccat cctaagccta ctactagatt ttttacagga ttattatctt
     9421 ttactaagct aactctttgt cctttttgta aactaacact cattttaagt tctccttttt
     9481 atatttttag ttttattgat ggtatcaagt ataagaacca tattagctat attatatacg
     9541 tatttaggct aagttggcta tatttataaa ttatttatta tataactaca tgaatatttt
     9601 ataatttaaa catattgaca ttatatgatt taaattattt tgtagtttta taatatttaa
     9661 atttgtattt gattgttata aagtaaagta agtaataaag ttagactcaa taattctaaa
     9721 atttctaagc acactatcta aatgagaacg tatttggaaa tacttgtata aaacaataat
     9781 tgatacattt aatttttatc ttaaaaataa caattataat atataaatag aaagtataat
     9841 atataaatag caagtataat ataacatata aaaagttgaa tttgtatatg ttaattatac
     9901 ttgctattta ttgttagtta ttctattttt ttaaatccat tacctaaagc ttcatgtata
     9961 tctgtaatta taataaaagc attagggtcg acatttttta ctaatttttt taattcgaca
    10021 acttctttct tttcaactac tactaaaagt acatttttat tttctccagt atatgcacct
    10081 tctcctttta gaatagttgc acctctatct aaatcttcca ttattttttt acttatatct
    10141 tttgaaaggt cagatataat agtgaatgat ttggaataat taaatccttc aataagcaag
    10201 tcactaactt ttactaaaat gtataaagcc acagttgaat aaagtgcaat ttcaacctgt
    10261 ctatttacta tacctgataa aacaactaca acgcagtcta caatacccat taaaacaggt
    10321 atactaaatg taggaaaata tttatttagt aggagtgcca ttaaatcagt tccacctgta
    10381 gagccattta ttctaaaaat aagtccttga ccaactccca ttaaaataga accagatata
    10441 attgcaagat acatatcatt tgttatatct aatgtagcca tatttgcagt aagcttaagt
    10501 gctatggtaa gaaaaattat tcctaaaacc gttttaaaac aatctttttt tgaaagtatt
    10561 ttgtaagcaa atatgaataa tggaacattt aaaagtaaat tgacaatcca aagttctaca
    10621 ccgaataatg aatttaaaac aactccaagt cctgttatac caccagcagc gattgcatgt
    10681 ggattaaaaa ataaattaag agaaatggcc attaatatac agcctacaat taatattaaa
    10741 atttctgaaa aagttattct atcttttttc aataacatca ctccttatat atagattata
    10801 atatatatta tatagttttt ccaattttta ataaaagaaa taaaaatata ttataaaaac
    10861 aatttgattg gaattttcag aaaattaatg ctataattaa aagtaaattt aaagggaggt
    10921 tataaaatgg ctaaattaac tctagaacat ataaaaggaa atacatatta tattccactc
    10981 cctacaatag taggtgtata cgtagatggt aaagatgcaa ttttaattga cagtggaaat
    11041 aataaggata cagctagaca agttttaaga ttattagaag aacataattt aagtcctaaa
    11101 ttaataataa acactcattc aaatgcagac catataggag gaaatgcata tttgaagaat
    11161 caaacaaaat gcaagattgc tacgactaaa attgaaggat attttacaga aaatccaata
    11221 ttagaatcag catttttata tggtggctat ccaagtaaag cactgaagaa taaattttta
    11281 ttagcaaagg aaagtgaagt tgattatatt ataccttcaa atggcaaaat tgtagataca
    11341 gaacttgaag cgatttctct tccaggtcat tattttgaaa tgattggtgt tagaactcca
    11401 gataatgttt tgtttgttgc agatagtctt acaccagaga atataattac taaatatcat
    11461 tttttcttcc tactggatat agattcacag tttaagacac tagaaaaatt gagaatgtta
    11521 gaggctgatt tctttgttcc aagtcactct gtcaaaacta cagatataaa aagtttgatt
    11581 aatattaata agaagaagat ggaagaaata atagataata ttaaaaaggt ttgttatgag
    11641 ccagttatga ttgatgaagt tattgaaaaa atgtgtgatt tgtacaatgt caagcttgat
    11701 gctaatcaat atgtgttggt tggaagtaca atacgttctt atataactta tttatatgag
    11761 aataatatgg ttgaatatat atttgatggt ggtaagatga tgataaaagc tgtgtaaata
    11821 gtaataattt tcaaattata tgatgaaatt gttttagtat gactgttatt tgaaaagtaa
    11881 cataaaaaaa tttatataaa taagctaaga tgattgatat aaagttactg ataattttaa
    11941 ggtaatatat acgttactat aatattatgt tattatttgt aaataagggg ataatttata
    12001 agcaaattaa agaccttaat ttacaggagg aatagtgtat attatgaata aaaaattcaa
    12061 aaaattcagt aaaaaactaa gtatattaat tttagttttg actatgtttc tttttaataa
    12121 tttaactgca aatgcacaga ttaaagaaga ttcaataata ggaattgata gatatgaaac
    12181 agcaggactt atagcagata gacaaactta tgatactgta atattagtta atggagataa
    12241 aaatttatct gatgggcttt catcaagtgg attagctgga gctattaacg caccaatact
    12301 tttgactaaa aaaagtgaaa taccaaaagc tactttaaat agactagata ataagagttt
    12361 aaatgttgta aaaaaagtat atataattgg tggttataat actattgaaa attcagtaga
    12421 aaaagatata aaaagaaaag gtattcaagt ggaaagaata aatggtaaca atagaattga
    12481 aactagttat aatgtagcta aaaaaataaa tgaagtaagt agtgtaaaag aggtaatgct
    12541 tacaaatgga tttgtaggag aggctgatgc tatgagtata gcacctgtag ttgcaaaaaa
    12601 taaaggagct ataatactta cagatgggaa atcagttcca tttaagactg aaggtttaaa
    12661 tgtttacgct ataggtggca aatctgcgat aaatgaggat ttagtaaatg aaactaaagc
    12721 aactagaatc ggaggaaatg atagatttga gaccaataaa aaggtaatgg aaaagtttta
    12781 taatggagcg acagattttt atataacaaa tggatatcaa ttagtagatg cactaacatt
    12841 atctccttta gccaaagaaa aaccaatcgt tttagttgct gatggaagta ataaaggtat
    12901 tttaaaagga gctaaaagta taacaaaagt tggaggtatt gatgccaata tatataaaca
    12961 gtgtttagat atgattaaat ataataatat ggatgtgact ccaaatattt taaaacactt
    13021 aacttcagtt gaaggaaatg aagtttctga aatacttata gaatcagata atttaggtgt
    13081 ggttgttgaa aagacgaata ccaataaatt tgagtttgat tacgtaagtg taactaatga
    13141 aaaaaattgt actttttctg tatataaaga aaattcttct aataatgtaa aaaatggaaa
    13201 gctagttgta agtgctaaga aaaaaataga taagaaagat agtgatttgc aagatatgaa
    13261 tggcgacaat atgataaatg caaataaaga taggatggta aatgtgataa aaattggagt
    13321 tcccgataaa atgtattcta attttaaagt agatgttgaa agtggttcag tagaacttta
    13381 taatattaaa ggaggagcta ctgttgatgt caatgacgga attgctaaca ttgttgataa
    13441 caatgtgaca aatcctttca atataaatac taatagtggg atttcaggtg taacagctga
    13501 aactatatca tctgagataa aatttagagc aaacaatgga attgtaagtg taacagctac
    13561 aaatataaat ggcaatataa gtttatttgg aagcgataat aaaggtacct ttgatggaat
    13621 atttaaatta aatctgaaaa aagaaccatc aaatttacac ttgaagttag ttggaaatgg
    13681 gataaataaa ttgccagaag gttggtctaa agattatatt ttaggaaatg gacaaccaat
    13741 tattgaagtt aaaaataatg gcataaataa tatatcaatt ggagaataaa aacatatgaa
    13801 aataaagttt atatagtttt aaaaattata gaattttaaa atatttatat atattcttta
    13861 aataaaaaat tattttttaa gtgataatta agtatttatc gataaggcta tggttgtaaa
    13921 aatcatagcc ttatttttat attataaata aattagagta tttatcaatt catagtagat
    13981 aaaattgaaa ttaaatataa caacaaaaaa tgaaaattac aattaattta atgttaaaga
    14041 ctcaattatt tggatgtgga atggatagta caagtagtat ataaaaagta ttgactggac
    14101 aaataactat attttatttt aaatatataa tataatgtaa taaaatatat caaatgtaga
    14161 aggtgataac ctatgaaaaa aataacaata aatgatattg ctaacttggc aggagtatct
    14221 aaaagtactg tatcaagata tctaaataat aaagatatca gtgattctac taaagagaaa
    14281 ataaagacaa taatagatga atatggatat gagccgaatg catttgctca aagtttgaga
    14341 gctaaaaaaa catactttat tggtattata acaccgtgtt tagattcttt tgtaaaatct
    14401 aaaattatga tggcaataga tgaagaactc aaagaattaa aatatacatc actaattatt
    14461 aatactaata gaaaaataag gtcagaaata gatagtatat caaagttagc tagtctaaaa
    14521 gttgatggaa taatactaat tggtaccgaa ataactaaag aacataagaa tgaaattgaa
    14581 aagttagata taccaatggt tgtagttgga caaaaagttg atggtatcaa tagcatagtg
    14641 aatgatgatt atggagcagg atataaaatg ggtcaatata ttgctaataa aggttacaaa
    14701 aacattgtat atttaggtgt tgatgaaagt gatatatcag ttggtttaaa tagaaaaaat
    14761 ggagtactta atgggttaaa agataaaggg tatgatgcaa aagtatttta tactgacttt
    14821 gaccaagaaa cgtctataca aagaagtgga gaaatgctag aaagtgaaaa tccagatata
    14881 ataatatgtg caactgataa tatagcaata gcaacaatga aagaaatcaa taagagaggt
    14941 aaaaatatac cacaagatat atctgtagct ggatttgggg gatatgatgt attgtctatt
    15001 ataagcccta aacttacaac aataaagttt gaaaataaaa atgcaggtaa agtagcagca
    15061 aatacgatag tgaacttaat acaagaaaga aaagaaccac tattaaagga gattaaattt
    15121 gaattaatag aaggtgaaag tacaataaat aaaaattaag atacacatta catatattag
    15181 taatgtgtat ttttttacta aaaaaactat aattctaaaa attaggaaaa cttttttgaa
    15241 agaaatattg catctgaaat aaatttatgc taatctttaa ttaaaccggt ttcgaaaccg
    15301 gtttaattaa accgaaagaa tagcacaatg agtgcaaaaa taactgattg taacaaagta
    15361 tcaaagtaat tattagagta cataggaaat aaacaaaata taaaaggtgt agcacattgt
    15421 gtaacaagat taagaattgt tttagatagt aataataaag caaatataaa attacaaaag
    15481 aaaaggaata aaaatatgta caaagagcct aaatatagaa ccatattaga atcgataaaa
    15541 gaagaattaa ataaattaag aaatatatct ttaaatgata aatataaacc actatttcat
    15601 atacatccac aacatggact acttaatgat ccaaatggat tagcatatta taatggtaag
    15661 taccatgtat tttatcaatg gtatccatat gatgcaactc atggaatgaa gcattgggct
    15721 tatgtaagtt ctgatgattt tgtaaactgg aatagagaag atgtagcatt aataccaatc
    15781 gaaagttatg aatctcatgg agcatattca ggtaatgcga tagaggtaga tggaaaattg
    15841 catatgtatt atacagggaa tataaaatat agtgcagaag atagatatgc atatcaaaac
    15901 ttagctataa tgaacaagga tggtaaaata actaaatatg aaaataatcc aatagtaagt
    15961 gaaataccaa aaggatatac aggacatgta agagacccaa aagtatttaa aagaaaggat
    16021 aaatacttta tgttacttgg agcacaaaca agtgataaaa aaggagttat aatagtatat
    16081 gaatctaaaa actctataga ttggaatttt aaaggagaat taaatgtaaa aaatatagat
    16141 gaagattttg gttacatgtg ggaatgtcca gattatatta atatagatga aaaagatata
    16201 ttaatatttt cgccacaagg agtagaacct aaaggatttg attatcaaaa tatatataat
    16261 gtagtatatg ctattggtaa tatggattta gataatttaa catttgaaat agatacaatg
    16321 aaagaactgg aaaaaggatt tgatttctat gctccacaaa catttataaa ggactcacaa
    16381 ataatactat ttgcatgggc tggaatggga gaagttttat accctacaga taaaaacaaa
    16441 tgggcacatt gtctaactgt tccaagaaaa ttaaatataa aaaataacaa gctattgcaa
    16501 atgcctgtag atgaattaat taaattaaga tatgatgaaa caagtgggca aaatactata
    16561 aagaataata tcaatattat agaaaatgat gaaaatgtat atgagcttaa tattaatata
    16621 aaaaatattg acagcaataa atttgggctg gaattatttt catcacaaga tgaaggtgta
    16681 aaattagaat ttaacaaatt aggaaacatt gtaactttag acagaagcaa ctttaaaaaa
    16741 gttttcggtg ttgaatatgg aacaaataga aaagaatata taaatattga tgaaaatact
    16801 aatatcaaag tactagcgga tagaagtgtt ttagaaattt ttataaatga tggagaagta
    16861 gtatttacta gtagaatatt tgctaaagaa aattctaatc aaataagggt ttatagtgat
    16921 aaaatagtag agtatgagta tactaaattt aaattaaagc aaggtattga attataaaaa
    16981 cacattataa ggggtagaaa agatgaaaaa agtaattagt ataggagaag ctttaataga
    17041 ctttatacct aatcaaaatg gttgtaaatt aaaaaatgta tcagaattta gaagagtagc
    17101 aggaggagct ccagcaaatg ttagtgttgt tgtagcaaag cttggaggaa aatcaagttt
    17161 tatatctaag ttaggaaaag atgcatttgg tgattatata atagatgtat taaatgaagt
    17221 aaatgtaaat actgattatg tattgagaac aagtaaagca aatacaggac ttgcttttgt
    17281 atcattaaaa gaagatggta atcgtgattt ctcattttat agaaatccaa gtgcagatat
    17341 gcttttagaa gctgatgagg ttaaaaaaga gtggtttaat aattgtcata tcttacattt
    17401 ttgttcagta gatttaatag atagtccaat gaaattagca cataaaaaag caatagaata
    17461 cgcacttgaa agtaatagta taataagttt tgaccctaat ataagattac ctttatggga
    17521 tagtgagcaa tcttgtaaaa aggcaatatc agaattttta ccttttgctc atattgttaa
    17581 gatatctgat gaagaattag aatttatgac aggagaaaat gatatagaaa aatcattaca
    17641 taaactcttt gtggggaatg ttgaactagt attatataca aaaggaaaag atggagtaga
    17701 tgcatacact aaaaaagtaa aaggtatgtg taaaggggtt aaagtaaatg caatagatac
    17761 aaccggagca ggagattctt atataggttc atttttatac accttattgt ataaacaaat
    17821 aacattgaat gatataaaag aaatgaaaca agaaacgtta aatgagtatt tagaattttc
    17881 taattattat gcagctcgta gtacaactat taaaggtgcg ataagttcat atgcaacaaa
    17941 ggaagagata actgaattta taaaaaattt atagtaggaa tgagtaatag gttttgaagg
    18001 aagtaacatg taaagagttt ttaaggatgt ttactatgaa aataattaac atataaaaag
    18061 caataaagag gctgtctcaa aatagatata agcctcttta tcattgttga aatgataaaa
    18121 aatattttaa ttattgttac tttttagaag aatatatatc ttattttaaa taagcaaatt
    18181 atgtaagatt tatttatatt atcaatactt tacttggagt attatgtctt tagcagttat
    18241 ctacttcaat tgaattatct aaaatataat aaatttgttt tgcaaattga cgagaatgtt
    18301 tttctttttc tttattcata aaattaggtt tacctaaatc acgttcaaca agcattccta
    18361 tatattttaa ctgtgaatgc ttacagtagc gcttcatacc attttcccaa atatcagcac
    18421 ccttttcagg tctatatcca catgttgtaa taagtgctac tggttttcct gcccatagag
    18481 cggggccttt ctcattacca tagtacttat tcattccata caccaatctg tcaagtagtg
    18541 ctttcattgg agaagtgcag taccaagaat aaattggagt agcaaaaaca attaaatcac
    18601 acataagaat tttcttgaaa attttctgaa catcatcttt acaataacat ccaaaatcaa
    18661 ataagttatc ctgacatttt ttacaagcaa tacatggctc tattttacaa tcatataacc
    18721 atattacttc aatatttgaa ttataatttt ctaattcctc aataaaaggt tttaaaatag
    18781 cagcagtatt accttttttc ttaggacttc ccataagaat gcatatttcc atattgatac
    18841 ctccacagta ttttaaaata gtttttagtg cttaatatag ttttaggata ctatgagaat
    18901 acgttaacaa caatacactt tgtatatttt taataaaatt gaaacaaatt gttttatcaa
    18961 taaaagttgg aatgtatcta taattaaaaa tattttaggt atgtttttac atatatgtgt
    19021 gtagttaact atggtaattt attgtaaaat tatcttatag gattataatt gcttaattta
    19081 tgattatatt taaaatcttg gaggtaaaaa atatgtactc aaatgaagac tataaattta
    19141 tagaagaaaa tgcaccatgt tatatatatg atgagactaa tataattgaa aaatgtaagg
    19201 aattgaaaaa taatatttta ggttttgatt ttttatattc tataaaaaca aatccatata
    19261 acaaaattgt aaaaagcatt gcagagcaag gttttggagc agatgcttct tcaactaatg
    19321 aagttatgat ttcatcagaa tgtggagttt ctaaatatga tatttattat tcatcaccag
    19381 gcaaaacaga gattgatata gaaactgttt tagataaatg cataattatt gcagatagta
    19441 ttacagaaat agaacttata aataagatat ctaaaaagca taatcagaaa gttaaaatag
    19501 gaataagaat aaatcctgat tttactatgg atgatgatag tgctaaatca agcaaatttg
    19561 gtatagatat agaagatatg agcagtgttt ttaagatgtt aagtatgtgt gattatgtat
    19621 ctgtagttgg gattcatata catattaaat ctcaggtatt ggattttgaa aagttaggac
    19681 attattatga aaaatgtttt tttatagctt taaatttaaa taaaagtaag tatattaata
    19741 ttgaatttat aaattttggt agtggacttg gagtagctta tgataatctt agagaaaatc
    19801 cacttaatct taaagagctt tcaaaattaa ctcaaaagat tgtttttact aattcaaaca
    19861 cactgaaatc aagacttctt attgaatcag gacgtttcat agtttgtaaa tcaggtaatt
    19921 attatgttaa aattgtagat attaaagtat caagagggaa aaaatatctt attgtaaaaa
    19981 atggacttaa tggatttatg agacctatta tttctaattt aattgaaaat attacttgtg
    20041 gagtagaatt agaaggtcaa gagccattat atacatcaaa tcatgccttt tctctttcag
    20101 tattaaataa tttaaaagaa gaagagtatg taaatgttgt tgggaatctc tgtacatcat
    20161 tagatgtaat tgcaaataat gttaaattga aaaaagcaaa tataggagat ttgatttcaa
    20221 ttagtaatgc tggaagttac tcctattctt tatcaccact attattttcg agttatgaat
    20281 ttcctaaaca atattataaa agaaaagatg gatatattga gtaaacaata ggataaatta
    20341 ataaacttag tattattgaa aaaatttaaa atgcaggggg tgtaattcta tatggaattg
    20401 tggaaaagaa atttatttgt atgttggata ggtatgtttt ttagttctat agggatgagc
    20461 caaatagcac ctatacttcc attatatatt aaacagttgg gggtaactga tgttagttta
    20521 atacaacagt attcaggtat aatttttgga tgtacctttg tagtagcagc attcttttcg
    20581 ccaatttgag ggaaagctgc tgataaatat ggaagaaaat caatgctttt acgtgcaagt
    20641 attgggatgg gaatagttat atttaccatg gcgtttgttc aaaatgttta tcagttatta
    20701 ggattaagaa tacttcaagg agtttttacg ggttatgcta ctgcatgtac tactcttatt
    20761 gcaacacaga cagataaaaa tcattcagga tgggctttgg gtactcttgc aactgcatca
    20821 actactggct cattaattgg tccaacagta ggaggatata tagaatcaat cttgggtctt
    20881 aaaagtacat ttattataac aggaggattg ttgtttgtat catttatcat ctctatttta
    20941 tttgtagtag ataattttaa acctaaagaa ataaaagaat caatttctat acctaaagaa
    21001 caattaaata tattgccaaa taaattttta attgcatcta tttttgtaac cacattcatt
    21061 actcaactag ctttatactc tatagaacca attgtaacca tatatatatc acaacttaca
    21121 aattttgcat caaatgtagc tttaatagct ggattgacat tttctgcatc aggattagca
    21181 aatttattag cagctcaaaa acttggaaaa atgtcagata aaataggtcc tcaaaaagta
    21241 ttgttaattt cacttttatg ggctgggatt atatttatac cacaagcttt tgtaaaaact
    21301 gcatggcaac tgatgttgtt gagattttta ttagggttgt cagttgcagg gcttaatcct
    21361 tctgttaaca gcttgcttaa aaaaattgca ccagaagaat atgtgggaaa aatatttgga
    21421 tataatgcat ctgcccagta tataggttgt tcatcaggag catttttagg gggacaaata
    21481 tcagcacatt taggtattag aacagtattt ttttcaacaa gtttattgtt gtttatgaat
    21541 gcactttgga tgtataaatt tactggattg tttattaaag ataagactaa ataatcatac
    21601 tatttacatt tctaatttta tgatgtaaaa taaatatttt ttatgtaatt tatcatagaa
    21661 ttatataaaa aataactcta tggtaaaaat tggaaaatat tattatcgac aaaatctttg
    21721 acttaaaaac tatattgcga tagtattaat ttaataaaag tttgagaggg gcgtaaggtt
    21781 atgacaattt caaaaatacc acaagcagaa ttaaaagtta tgaagtttat ttgggaaaaa
    21841 aatgatacag taacatcaaa agaaactatt gaagctatgg aacgaaaata tggttggaaa
    21901 caaacaacta cattgacact tttatcaaga cttgttaaaa aacatttttt aagtgcagaa
    21961 aaaatagata gatacactca ttatacaata gttgttggac ataaggagta tttaagtgtt
    22021 gagacaaaag attttttaag caatatacac gacaattctt tacagagttt aatttcagca
    22081 ctacatgatg atgaagttgt tgataaagat atgttggatt tatttgaaag tcattttaaa
    22141 aatttagaag aagagtaatt atatcaggat aaaactctaa gaatttaatt aatctatggc
    22201 tgaaaaccat aaatggtatt atttaatcag ctactcacta ttcataaagt aatattaaat
    22261 aggttctcta attagtaaaa tacctaaaat aattggaata gggagtatca agttaaatga
    22321 taccacttat ttaaataaga aatgattttt aaaatttaaa ataattttat aacttgtcaa
    22381 tattcattaa tctaaagtat tatttctatt taaccatatc aaaatatatt ttactatttt
    22441 taattattac aatataaacc tgtcttttgt tattataggt aaactaaaag taagaaatga
    22501 tttttatatt tttaaacttt attattggta acttatc
//
LOCUS       DAEQJM010000057        22045 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.057, whole genome shotgun sequence.
ACCESSION   DAEQJM010000057 DAEQJM010000000
VERSION     DAEQJM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22045
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.057"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            1..468
                     /locus_tag="KRQ43_002751"
     CDS             1..468
                     /locus_tag="KRQ43_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH2743096.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFILENVKRFKVMGCCLLINTIIECVIG
                     YNSNTSLIMIFGDNSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            479..694
                     /locus_tag="KRQ43_002752"
     CDS             479..694
                     /locus_tag="KRQ43_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743097.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(1464..1748)
                     /locus_tag="KRQ43_002753"
     CDS             complement(1464..1748)
                     /locus_tag="KRQ43_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743098.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGRICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     repeat_region   1859..2542
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1985..2012
                     /rpt_unit_seq="tttacattccatatagttaatataaaac"
     gene            complement(3373..4245)
                     /locus_tag="KRQ43_002754"
     CDS             complement(3373..4245)
                     /locus_tag="KRQ43_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH2743099.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(4639..5217)
                     /locus_tag="KRQ43_002755"
     CDS             complement(4639..5217)
                     /locus_tag="KRQ43_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH2743100.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(5275..5991)
                     /locus_tag="KRQ43_002756"
     CDS             complement(5275..5991)
                     /locus_tag="KRQ43_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH2743101.1"
                     /translation="MRINKYIASCGIASRRKSEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            6182..7267
                     /locus_tag="KRQ43_002757"
     CDS             6182..7267
                     /locus_tag="KRQ43_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH2743102.1"
                     /translation="MIIILKENIKYYLIVVFIGILFFKFINTPSNFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(7422..8081)
                     /locus_tag="KRQ43_002758"
     CDS             complement(7422..8081)
                     /locus_tag="KRQ43_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743103.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KYSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(8298..9590)
                     /gene="lysA"
                     /locus_tag="KRQ43_002759"
     CDS             complement(8298..9590)
                     /gene="lysA"
                     /locus_tag="KRQ43_002759"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBH2743104.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(9608..10801)
                     /locus_tag="KRQ43_002760"
     CDS             complement(9608..10801)
                     /locus_tag="KRQ43_002760"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH2743105.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(11162..11779)
                     /locus_tag="KRQ43_002761"
     CDS             complement(11162..11779)
                     /locus_tag="KRQ43_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743106.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(11949..13649)
                     /locus_tag="KRQ43_002762"
     CDS             complement(11949..13649)
                     /locus_tag="KRQ43_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743107.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(14046..14609)
                     /locus_tag="KRQ43_002763"
     CDS             complement(14046..14609)
                     /locus_tag="KRQ43_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743108.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(14768..15481)
                     /locus_tag="KRQ43_002764"
     CDS             complement(14768..15481)
                     /locus_tag="KRQ43_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HBH2743109.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            15773..17437
                     /locus_tag="KRQ43_002765"
     CDS             15773..17437
                     /locus_tag="KRQ43_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HBH2743110.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDSKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(17544..18443)
                     /locus_tag="KRQ43_002766"
     CDS             complement(17544..18443)
                     /locus_tag="KRQ43_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBH2743111.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(18470..19108)
                     /locus_tag="KRQ43_002767"
     CDS             complement(18470..19108)
                     /locus_tag="KRQ43_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH2743112.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KVGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDEELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(19445..20443)
                     /locus_tag="KRQ43_002768"
     CDS             complement(19445..20443)
                     /locus_tag="KRQ43_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HBH2743113.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(20541..21116)
                     /locus_tag="KRQ43_002769"
     CDS             complement(20541..21116)
                     /locus_tag="KRQ43_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743114.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            21432..21695
                     /locus_tag="KRQ43_002770"
     CDS             21432..21695
                     /locus_tag="KRQ43_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743115.1"
                     /translation="MIKNTKQITVEVNEILLQEISKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
BASE COUNT         7359 a         3554 c         2283 g         8849 t
ORIGIN      
        1 atgattacaa aattttttag taatatatta tcagtatttc tatattttct attatcactt
       61 ttaggagttg ctggtataat attcttatgt atgataccta tgtttttata tgattttagt
      121 tctgacaaag taatcgcttt aattgcaaga atactatatt tttctgacta ctttatagtc
      181 atcttattct tgatatttat aattaatagt actaagtatt ccccattcat acttgaaaat
      241 gtaaaaaggt ttaaagtaat gggatgttgt ttattgataa acactataat tgaatgtgta
      301 attggttata actcaaatac tagtcttata atgatatttg gagataatag tggcggtatc
      361 tcaccactta tggttatttc ttttatattt gcactaatgt gctttgtaat tgcagaaaca
      421 tttgataaag ctataaaaat aaaagaagat aatgatttaa cgatatagag gtgatgttat
      481 ggcaatagta gttaacctag atgtaatgat ggcaaaaagg aaaatatcac ttaaagattt
      541 ggcagaaaaa atagatatta caaatgcaaa tttatcaatt ttaaaaactg gaaaagcaaa
      601 agctattaga tttaccactc taaacgaaat ttgcaaagct ttagactgtc agccaggtga
      661 tatacttgaa tatgtagaag atgaaaatga ttaaaaaaga gtgtttagaa acactctttt
      721 ttattatact atatgatttt tattctttta ctatattatt gacattaata ttaactttgt
      781 ttaaagtcat aacaaaatac gttctaagaa agaaactgtt cctttttcta tttgttatcc
      841 attacctata agaactgtat cacactaaat catactttta aattgataat tttgccacag
      901 attcctatat acattctttt ctacctaata tttatttaaa ctgttagcaa aacatggaac
      961 tttttcattt acttatacct ccatttatat tattgcatag tttatagcta cgtgttataa
     1021 attacattat tgatgattta tctaacattt gtaatctttt agatactctt tgaagttaca
     1081 acactgttat actctaatta agtaaactaa atctgataca agttggtgat tatatgaaaa
     1141 gaaaactttc aacctatttt aaaggatata ttttaggttt atgtatagca tttttattat
     1201 ttacttttat attaaaaaaa ttaattatag aaaatatcat tggaataata attggaactg
     1261 gaattgcatt tttactgatt tacctattta ataaaaaaag aaaataatat tctataaaaa
     1321 ggtcttttag tgaatttaca aaaaattaat aagaataata tatacttagt atttaaaaag
     1381 ggtaacaact ctctctagct gttaccttat atatttatct atatctttag tattaagttt
     1441 tttaatttct acttttttaa ttatcaattt ctgtatgtag atatactaaa ccttccaact
     1501 tgagatttaa ataacttttc aatctcataa actattctat acaccttatt ttcgtactct
     1561 aaatcataat acacatttat ttcacctata ctgtttacac ttatcgtata atgttctttt
     1621 tctattatac atattcttcc aaaatctgac aggtcattat ctatcaattt taactgtttt
     1681 tttatttttg aaaaatctaa tcttggaaat atgtcattag gataaaaact tttattatat
     1741 acaagcattt catccacccc ttatttattc tatttatatc attttatacc ctaattaata
     1801 atttattaat catctttttc catattattc aaattctctt atataaaaac aaaatcaatt
     1861 tagaatatgt attattaaat ataaagtgac tcaatcttta tttaataaga aaaaacattt
     1921 atattacata taattaatat aaaactaatg aagtgggtgt atgaaagaga aaacacaatt
     1981 ttaatttaca ttccatatag ttaatataaa acagttgttt ttattttttc taaagagaaa
     2041 aaactagact ttacattcca tatagttaat ataaaacttt ctgtatattt tagttgtgtt
     2101 ttaatattat aacactttac attccatata gttaatataa aacatggcag taactaagaa
     2161 gaaaactata ccttttttat tctttacatt ccatatagtt aatataaaac gaggaaattt
     2221 tatactaatg actgatgcta gatttaactt tacattccat atagttaata taaaactatt
     2281 ataaggagca ttatacgacc aaaagccaaa gcagctttac attccatata gttaatataa
     2341 aacaagcaac agcaagagtc gcgacaacat taaaaacttc ctttacattc catatagtta
     2401 atataaaacc tttatttttt tctctatatc gagttcgcca aattcactct ttacattcca
     2461 tatagttaat ataaaacagt ccagcgttgt gtggtcgtaa cacaccaatc ctactttaca
     2521 ttccatatag ttaatataaa accccaaaat aaattaagta tttccaatac ttatacatat
     2581 acaattctcc taaacttgca gtgagcgagc aatagtgcaa ttgataacag ttatcataca
     2641 ctctcaacgc tttatatttc aactattaaa ccctacttta tcacaaaaat cgctcactgc
     2701 aaaactttta tatttttatt atatcataaa actcatacta taaaataaaa atgggataat
     2761 tttacaaact aaaagcatct acattcttat aagtatttat tatattctct attccaatga
     2821 ttcctttttc tttttattgc atccttccta tgtaatcgca ctttagctca acaagtcttt
     2881 tattttcatt aacaattttt taaactattc aaaatcatca aatttttcat cttatacagt
     2941 taaatcaaaa tacgtgttat atctctttat ctatatactt ttcttccttc catttctttt
     3001 tctctttcta cattttcact ttgttacttt acaatctcaa ggttattatc tgctattaaa
     3061 gttttatctt tccaggtttc acaaaaataa attgaataag tgcaaaaata acagatacaa
     3121 aaccataact attttctttt ctataaaaaa atatatcatc aacaagaaac ataataaatg
     3181 aaaataacta tgaataaata ctctcattta gaagaaatag acaaagatat tccttaaaat
     3241 ttaagcaaaa tattgtttaa ataaaaaaac tgactgtcag ttaaatgcca gtcagctatt
     3301 ttatatattt tatccaaaca tcactatatt tgaacatttt aataattaat aatacttatt
     3361 aatatacaaa ctttactcat acacagaata tcttttccaa atttgctcta aatcatcaaa
     3421 atgctgttta atatcttctt tttccttcat tccaacagat atagcaaggg catttgaaat
     3481 actaagagct ggaactagag aatctacaaa tgaagccata ttactcttaa ctagaagagt
     3541 gttatctgca agtgatgcta ctggcgcaaa taagctatct gttaatgata ttacatgggc
     3601 tcctttttct ttagcataat tgacaatttg ataagatttc ttagaataac gagggaaact
     3661 aatagcaact attacatctt cttcatttat tcttacaatc tgctcaaaag catctcccat
     3721 atccattcta attatatgaa cattgtcaag tattatatct aagtaaaaac ctaaatattg
     3781 agctactaca aaagaactcc tcattccaag tatatatatt tttctcgctc ttaaaagttt
     3841 gttagaagct tctttaaacg ctctctcgtc aatttcttct agtgtagacc ttatattatc
     3901 tatatcactt tttaaaactt tgtttagtat tgcaaaatca tcggaataat catgtgccat
     3961 ttcaactctt tgtactgtag ttagtttatt ttttatgagt tcttgaagtg cagcttgtaa
     4021 tttaggatat ccactataac ctaatgcatt tgcaaatctt acaactgtag actcacttac
     4081 tcctacggtt tcacccaatt tacatgcagt cataaatgca actttatcat aattatttaa
     4141 aatgtattgt gctataagtt tttgaccctt actcaatctc gtatattgag attgtatatt
     4201 tgatatcaaa tgtttactgt ccttcatttc atttgtttct tccatttttt tctcctttta
     4261 gttatataaa ctattttgtt ttattaacac tgtctttttc tctaaaaatt ttatttttta
     4321 tctcaatttc atcttagttt ttatcatagc ttcttaaact cataaaattc taacttttct
     4381 gtaccttata cttcacatag tattttcgat taaatttatt ataccatctt tccttgcatt
     4441 ttttaatatt tatccaatat ttcttttaaa tttttcaatt tttactcatt taaaagttat
     4501 ctatcttatt ttgcatattt agatgtatat tttgttttga gaataagctg ttgtatactt
     4561 attatttaaa gtatttttaa taggtcacac tatatatatt aactcttaat agaatcttgt
     4621 caagtttttt agtatttatt atgctttttt cttttcaatt aaaatcaatt gtggtgggtt
     4681 attgacttga tttaaaaact tagattctaa aacattaaat tcatcttgat ttaaattatt
     4741 gacaaggtta tatatgcaat ctttttcttc ttgacctcca tcatgccctg tatatatggc
     4801 aatgcttatt actccatttt cttttaacat ttctaaactt aactttatag cctttaaagt
     4861 tgtatctggt ttggttataa ttgaatgttt cgctcttgga agataaccca aattaaataa
     4921 aacacatgaa acttcttctt ttatatattg attcattttt tcatgcccat caaatatcaa
     4981 ctttactcta tctgtatatc cttctttctc tagtttcttt cttgtagact ttattgcttc
     5041 ttcttgtata tcaaaagcat atacaaagcc cttttctcca accttctcag ctagatacct
     5101 tgtatcatac ccatttccca tagtagcatc aattactatg tccccttcat ttataatatt
     5161 ttctaaataa aatttattta tatctgtaat tttagttaaa tactttgcat atgccataat
     5221 actatttctc cctactatta actttatttc attttttctc aatttatttt tatcttattt
     5281 tattgatttt aaatatttta tttcatcttc tgttaggtat ctatattctc caactttggt
     5341 gtcttttaat actattttcc ccacagaaat ccttcttaaa tttaaaactg gatgatttat
     5401 agctttgcac atttttctta cttgtctatt tctaccctca tgtatagtta tttcacacac
     5461 tgaataattt ttttctttat tttctttagt tacccttatt ttggcaggtg ccgttgtgta
     5521 atcttctatt tttagtcctg tttcgaattg tcttatctca tcatcactta taattccctt
     5581 cacacttgcc acatacgttt tatcaatttc atgctttgga tgggtaagct tatatgttaa
     5641 atcgccatca ttagtaagta ttaataaacc actagtttca taatctaatc tccctattgg
     5701 atatactctt tcccttacat ctttaagtat gtctattaca ctgggtctat tgaattggtc
     5761 ttttactgta gttatatatc cctctggttt atttaatact atatatatat aattttcact
     5821 tggttttact tttttattat caaattctac tatgtctttt tcttcatcaa tattaaaaga
     5881 taactctttt actacacttc catttacctt tattcttcct ccaagaatta tttcttctga
     5941 ttttcttctt gatgctattc cacaagaagc tatatactta ttaattctca tacttaatcc
     6001 ttccttatct taaattatgt gtgtttaata tttttatcaa tgttaatttt gctacattat
     6061 tatactatac tagaccttaa ttaaaaacaa gcaaaaaaat tatttaattt tcctaaataa
     6121 ttgtaatttc ttttcacata ctattaatat gtaatagctg actaaacact attttaagga
     6181 agtgattatt attttaaagg aaaatataaa atattattta atagtcgtgt ttattggaat
     6241 tttatttttt aaatttatta atactccatc aaactttata tctagtattg aaggattctt
     6301 aaagtttttt agcccatttt tattagctat tttacttgct ttacttttaa atccacttgt
     6361 gatgcttttt gaggtaaaat tcaaagcaca tagactttta gccatttttt tatcttatat
     6421 atttataggt tttattttag cctttgccat taggctatta attccatcaa tagctaatac
     6481 attaaataga ttgataaatg aaatgcctat gtatactgat tatatagata gttttataga
     6541 aaaaaatatg tcaaacatag attttctaaa aactttaatt cctcatatac aacatagttt
     6601 agataattta ttaaaagaag caagtaattt tgttggtaaa attcctaaaa acttcttaat
     6661 ctatacactt agtatatctt ctatgctatt taatatgaca atgggattta tactatccat
     6721 atacattata tatgacaaag aaaaaattgc attgggattt aagagatttc tatattcttc
     6781 tactgctaga aacaaggcag ataacattat agaatttttt aggactactc atgatatttt
     6841 ctatgattat ttacttggta gaatattaga ctctcttatt attggtataa ttgcattttt
     6901 aggatttcaa tttgttatca gaatagaaaa tgctttattt ttagcttcaa taatattctt
     6961 aggtaatata attccctatt ttggtccttt tattggtgca atccctccaa tagccatgac
     7021 tatattatat agtccacaaa aaactatatg ggtcattgca tttctattta tattgcaaca
     7081 attagatgga aattttatag aaccaaaagt tatgggtaat caagttggta taggagctat
     7141 atgggtaata tctgctattt tggtgggaca atctctattt ggtttcatag gagtttttct
     7201 ttcagtacca atagctgctg ttgtaaaaac ttatgttgat aaatatatag ataatcgttt
     7261 acaatagctt atctctactg tgactttaat ttttagttta aaatttaact gttatttatt
     7321 aaattatttc tcaaaaaata tctcttagta agaaaaaatt gctaagagat attttttata
     7381 atatataatt tgttcattaa atttatgcat atattttata cttattgatt atttgagttt
     7441 tgagaatttc caccactatc tgaaccacca gtagtatctt gtggagttgg tgctggtgtt
     7501 ggattactat tatttggctt ttcttgattt tgagaagaac tgttattatt gtcagactta
     7561 ttactatctg attttttatc attattttta gaactatatt tattattttt actacttcca
     7621 ctataagaag atttccttgc atctgattca actctatacc tatcttctcc agccgtatct
     7681 tttgcctttt tctttctttg ttcctctgct tcgttttgtt ctttttctaa tttagttaac
     7741 tcttctttct ttttagttgc ctcttcttta ataacagagg aaccattttt gattttctct
     7801 ataagtttaa gttccttgat tgcaccctca taatttttta attcttcaaa ctccgtcata
     7861 tttgacattc tcatagcttg catatacata gctcttgcat tctcattagt actatcttct
     7921 tccagtgcag aggataatga ttccatagct tttttatagt tatgtttttc taaatatgtt
     7981 tttccttgct ctactaaatt tatttcatct tttttattaa atgaacatcc tacaagaaat
     8041 atagataata tcgatattaa taaaattact cttcctctca ttaaatccct ccttgtcata
     8101 tactttaaat tttatcataa ttataaagtt tttaaaatat tttatattta ttacaagaaa
     8161 tttgttagta aaacaaaaaa taagcagata tgctacgaac gatacaataa accaaaaatt
     8221 aatttagaga tacatatcct agcaaatctg ctcataataa actttaatat ttaattttta
     8281 ttatatactt ttccatttta tatctctaaa gctaataagt cctcatagct ttgtctctta
     8341 caaattatct tatcatttcc atcaaatact gatactactg ctgctcttgg tattttatta
     8401 taatttgaag acattgaata tccatatgca ccagttgatg ttgttataag tatatctcca
     8461 cttttaatat ccattatgtt tatatctcca attaatatat ctccactctc acaacatttt
     8521 ccagctattg ttacatgatt catagcctca tgattaattt tattcacaat actacactca
     8581 taactagctt ggtacaacga aggtcttaca ttatctgtca tacctccatc tacacttaca
     8641 taaaccctaa catcttttat atcttttata gaacctactg tatacaatgt acttcctgca
     8701 tttgcaacta ttgatcttcc tggttctatt accaatgtag gtacttctat tccaagctct
     8761 ttacatgaag tttctgcttt agtgattatg gtttcacaaa actcttttat agttttaggt
     8821 ttatctcctt cgctataata aacgccaact cctccaccta agtcaatttc tgttagttgt
     8881 atgttgaatt tttcttttat ttcttttacc aagttcatca ttatatccac tgtatctatg
     8941 tatggttcta catcaaatat ttgtgaacct atatgagcgt gaagacctac aagtttaata
     9001 tttttatatt cacttaattt ttctattgct ctaaataaat ctccatttac taaagcaaat
     9061 ccaaatttag aatctatctg tccagttttt atataatcat gtgtatgagc ttctatacca
     9121 ggagttattc taaagtatat ctcttgagtt ttacctttat cttcacataa tgcttcaagc
     9181 aaatctaatt cataaaaatt atccactaca aatttaccta cacctaaatc taatcccatg
     9241 tttatttctt ctttagtctt attgtttcca tgaaagaaaa ctttttccat aggaaaattt
     9301 gatttataag ctgtatataa ctcgcctcct gaaactacat ctaaacacat ttgttcttca
     9361 tttataagat tacacatgta aagaggtaaa aaagctttcc ctgcataagc aaccttattt
     9421 tttccctctc tagccttaaa atattctata tattctctac aattttgtct aactaaagct
     9481 tcatcaaata cataaagtgg agtttgatat tttttactaa gttctaaaca actcactcct
     9541 ccaatatata attcatcatt atttacagtc atagttccat gaagtttcat aatagcctcc
     9601 ccaaatttta tatattaaat acttctgcta ttttttctat agctacttgc ttatcatcag
     9661 aatttatagc acaagttata cgaatctctg atgtagttat aagttttatc attataccat
     9721 tttcattgaa tatcttaaat actttagcag caactccaga agtatttttc ataccaagac
     9781 ctactaaaga aaatttagtg atattattat caatcactac atgttcttca tctgtatatt
     9841 tagatactat ctttttacat tctcccaact cttcttttgg aactgtaaat gatacactta
     9901 tcttatctaa aataggtgca gtttggctta tcatatctac acttatacct atagttgcta
     9961 tatcttcaaa taagctagat atattttcag ctttaaaatc ttttattgtt atagaactgt
    10021 catcatcact agtagctaat cctgttatta ctttatcctc taatttcatg tcttttcccc
    10081 ctcttatata tgttcctttt tctgtaccac atgtacgtcc gacatagatt tcaacaccat
    10141 atttttgtgc aagctctata cttcttgaat gcattacttg tgctcctaaa ctcgctaact
    10201 caagcatttc ttcatattca atctcatcaa gtttactagc ctttgaatat tttcttgggt
    10261 ctgtaaaata aattccatca acatctgtat atatctcaca ttttccattt aatttaaccg
    10321 caagagctac agcagacgta tctgaaccac ctcttccaag agtggttaca tcaccatctt
    10381 cgttgattcc ctgaaatcca gttactatca cgacatttcc ttcatctaaa ctatttttaa
    10441 ttctgtttac gtttatatca tcaatttgag actttccatg aagaccactc gtttttatat
    10501 ttaactgata agcattataa cttatagctt tacatccaag tgcatttaat gctattgata
    10561 ataaagatgc tgaaatcatt tcaccagtag acattaaagc atctaattcc ctcttactag
    10621 gttcattact caattccttt gctaaagtta tatattcatc agtggatttt cccatggcag
    10681 acacaactat taccatttgt ggattttctt ttcttcgttc tattatattt tctgctattg
    10741 attttatttt ttcagtatct gctactgaac ttccaccata tttttgaaca attatactca
    10801 tgctttctcc ccctcaagct aaattttgat aaataaaaac gcccaaaggt atactttgga
    10861 cgtgtaaatt tcatagacca agtaaccttg tagctcacca ctttaaaagt gacagcctta
    10921 tgcatattct gcataagtcc agaaaatttg tccgtcaaca aaatttcttc ggctatatac
    10981 cctttcatca attatcaatg cttaccagct cctattgaat actattgaat acagctacct
    11041 ctaccctagg ctcattattt ttaattaatt tattaatata gttttatcat attctatata
    11101 atattgcaac aattatttta caaaatgtgg caaatcgata gttttctttt ctaaagttag
    11161 cttatataca attaaatagt ttatttaatc ctaaatctat aaaatttatg ctatactcat
    11221 tatcatatct ctctaaatca tttaattcgg atagattatc tggtgtaact accaaaacgt
    11281 ttggtacttt aaaaaatgga attgtagatt tatctatttt tttagaaaga ttttcgtatt
    11341 tagaaatgtc tatttcatta tttaagtcaa catcaactaa aacttgcttt atattaccaa
    11401 attggtctgt atattcaata aataaatcgt atttcacatc atctacacta acatttcggt
    11461 aaaatctttt tacatcacaa cctgcagtat tgattctaac aactaattct gatcctacta
    11521 gagcctttat taaatcatct cccttaaaaa gtttactacc gtttaaataa tatacataag
    11581 agaggtcttt ataattataa taatccacat cacaaggata tttttttagt gtatattcac
    11641 tacacatttt tctcaaagtt tttttaaaat tttttttatt gtatcttttt tggtctccat
    11701 aaatttttct aaattgagac tctgtaacac atctaaccct gctaattaaa agtaatatct
    11761 ctttttccat attcgtcata gtacattctc cttgaagtat tatttgcaaa gttgtactaa
    11821 tattatatta attttatgac attaaattta caaagaatta aaataaaata gctaattttt
    11881 atagaattaa attctataaa aattagctat cactatgtta aatactatta tcaatctttt
    11941 tatttaaatt atacattacc ttgattttca gaatctttgg aatctgtatt ttcatcagtt
    12001 cctgtttttt cttttgcttt tttatcttca aagtttgcaa tatttaggtt atcaaattct
    12061 gacatttcta ttacaccaga ttcttctttt gaatacgata ttttgacttt atcaccaacc
    12121 tgagtcaatg gcaattcgct agatactttt gaagtagccc taaatattat atctttattt
    12181 gaatctaaag ttacataata attagtgtta ccacctcgca catctgggct tattcttgtc
    12241 actgtgcctt ctaatacctc atcttttaaa tcattatcaa gttttaaatc attaccctta
    12301 gattctaatg catccttata gtttcttaat gcttcattct tatcttcacc tattccaagt
    12361 acattataat cttcaacaga tacaaatgca actctcttaa caagaccagc cttatctttt
    12421 aatgatgata catatgttgg ctgacccaat atattataca ttacagggaa cgtcgcttca
    12481 taattttttt cttgaacatt accttcagct gatttcattg cagccgtttc agtagctcct
    12541 ggttgtttat ataatctagc ttcttttgtt ctagaatcaa ctaacataaa tccaattgta
    12601 gattcatctc cacctgaaga tgttatacct gtataccaat aagacctgtt atcattgcca
    12661 taaactaatg atgtaccttc tgttggtact aaaactccct tttctgatat aacagagttt
    12721 aaaaatccat taacataaac accccagtct ttaatctggt ctgttacaaa gctttgtggt
    12781 tgtattctat ccacccattt aggtgtgttt ttaacatcat aaacatttat ttttccagtt
    12841 tctgcatcaa cagtggctat tcctgttgca tttgctcctc catagccaat tttatgttca
    12901 tataaactta caacccaata aggtcttcct tcatcattta tttcaagagt gaaatctgtc
    12961 ataccaacat ttacaatacc atgtatgtat aaatgtcttt gtaaatcctg atgtaagtag
    13021 gcttctggtt ggtaaactat ctttattggc tttccatcta tttcttgaac taattggacg
    13081 tcttgaggat tactagctga tacttttaca taaccacttg taccacttag agatgttatc
    13141 catttaatta tgtctctgtg aacaagaggc gctacccagt acaactctcc atctacattt
    13201 tgtatatgaa attttcctaa tttggataca ctccctattg caggaacttc tccaagcttt
    13261 ttgtcaccta atttcattgc catatcttca tctacaagac gaatgtcatt tacactgaca
    13321 gggctaatgt catcagtaaa tttactttca gttacttttc ccaatagttc tctatatgat
    13381 tttgcatgaa gtacaggtgt agaagttata aagggaacta ctacaatata cacaagcaaa
    13441 gctattgcta ttgaaaaatt atatttagcc attttagatg ctctttcatt tctatctaac
    13501 atcatatcta gtattcctgc tacaacaaag aaaattattc ctactgaaaa taaagatgta
    13561 aaatctaatc ttagtacagg taatttaata aatgcataaa ttattacaat tattaatgca
    13621 actccatatg ttttaagata tcgtttcatt taatactcct ctctaaaaaa tgttattatt
    13681 attattatat ccatatattt acaaaaaata aatatttatc atatttatta tatattaaga
    13741 tatctttata tatttatagt tctgcttatt caactatatt taacattata cgtgtatgta
    13801 taaatacttt ttatacactg tttgtgctat ccatcccgca cctaaaggag tgggattttt
    13861 gcactattct gtattatata tatccaaaaa tattataaaa atacaaatat tagcagaaat
    13921 ttaaaaactg aagaaagtat tctaactaag atttacaaat tcttaatcct atcgaagtta
    13981 aactactatc ttcagcctaa ttatctagca atattttttt atatgaaaaa ctctaaatca
    14041 agtttttaaa tgtttgcgat ttttgataca taagaatgtt gtctagaatt atattctgat
    14101 aataaacctt catactctaa ggttaagcca gataaattat aaaaatcatt tggcgttact
    14161 tcaaatgctt gtttatttaa aatgtctatc tcactttttt ctaacatgtc agcaacaaag
    14221 tttgaacata catatttata ttcagattgt ctctgaatat tcattagtaa atatattaat
    14281 gccattgtat cgtaatagta atcttctcta taatcactaa ttaattttat atttttatat
    14341 agattttcat attgtaaatt atctacttct aacgaatata ccctacacac agtgtttttt
    14401 cttatagcat acaatccttg atttatattt tcttcaacaa atcctccaat aaatggattc
    14461 cttggattta gccttccaaa agaatacatt ggttttagat tttcatttaa tgatattgac
    14521 acatgtgtat acagcttttt acttatattc cttattaagt aagataatat agttcctgta
    14581 tatgttgtta caatatagac tttattcatc atttcccccc aatctagtaa ctaaatgata
    14641 ttatacactt acaatttaat atcataagat attctaacat aataaatgtg gttttacaaa
    14701 ttttgatttt aaggtacttt aatattatat aatataataa aaatataaat ataagttttc
    14761 tatattttta accaacagat gttttcttca aattaatcag atgatttagt atatcttgaa
    14821 cctttccaga gtcctttaaa tatcctaatg ccccatttat ttgtgatttt aaatctattt
    14881 ctacttccat atccaaatca acatttcctt tttttataga tatattttta agtgttattg
    14941 ggtaaagata acttttttcc aaagtaatct tatttccatt aacctcaaat ggaacttttt
    15001 tattgtagtt acttaatatt ttttctagca ttttatcact tagtttaaat tttccaattt
    15061 tcacattctc aagacttaca actaagtttc catcctttaa agtaggtctc aattcaagtt
    15121 catattgact atttaccaaa ccaaatacct tatatggtcc tgctaccttt attttaccat
    15181 ttttcatttc aacaaaatta ttttcaagtt cattaattcc atgcttctgc atcaatgtat
    15241 atattaaatt tttaaactct tcctctgaaa cagatatttt tccaaccatt ctaagtggat
    15301 tttttactac ctccatagaa tttatatatg agccttttga taaatattct tcatctatga
    15361 ttttattatt ttgtgaacta acatcatatc tttcttttgg tgtcaagata tatacaacaa
    15421 ttcctgcaag tactaaaaca ataacaatta aacttaacaa aatctttgca acctttccca
    15481 taatcgtctc ctttacaaat ctgtcatcag atttaaaata aatttagata actaacttca
    15541 cataatattc ttaacaatat acatactata atacagtctt ttaaaaatta attcaaccaa
    15601 tctaatgttt tgtaaataaa ctgtaaaaac atgtttttag tataaaagtt aatattttgc
    15661 ataatactct taattacacc tttatttttt tctaatcttg gattaaaatt aatattatgc
    15721 aatacagtgt agtgttctgt attataatca aattaaatag gaggtataga atatgtcaaa
    15781 tgaaacgaac tcatctaact ttataaagaa tattattata aacgacttag aaacaggaaa
    15841 acatgacagt atcataactc gttttccacc tgagccaaac ggatatttac atattggtca
    15901 tgcaaaaagt atatgtctta attttggatt agctaaggag tttaatggaa aagctaattt
    15961 aagatttgat gatacaaacc cattaaaaga ggatgttgaa tatgtagagt ccataaaaga
    16021 agatgtaaag tggttaggat ttgattggaa cgagttaaat tttgcatcta actactttga
    16081 tgaaatgtat aagagagctt taatactaat aaaaaagggt aaagcttatg tatgtgattt
    16141 gacacaagag gaaatgagag aatatcgtgg tactctaact gaaccaggaa aagaaagtcc
    16201 tcatagaaac agaactattg aagaaaacct tgatttattt gaaagaatga aaaatggtga
    16261 atttaaagat ggtgaaaaaa cattaagagc caaaatagat atgtcttctc caaatataaa
    16321 ccttagagac ccaattatat atagaatatc tcattcaaca caccataata caggagataa
    16381 atggtgcata tatcctatgt atgcttttgc tcatccaatt gaagatgcaa ttgaaggaat
    16441 aactcactct atatgtactt tagagtttga agaccaaaga cctctttatg attggtttgt
    16501 taaagaatgt gagatggaaa atatacctag acaaatagaa tttgctagac ttaatataaa
    16561 taatactgtc atgagtaaaa ggaaattaaa acaacttgta gatgagggta ttgttgatgg
    16621 ttgggatgac cctcgtgttc ctacaatatc cggaatcaga cgtaagggat atactgcaga
    16681 agcattgcgc aatttctgta gtgaaatagg ggtatcaaaa gttaactcta cggtagatag
    16741 tcaaatgctt gattatttcc taagagaaaa cttacaacca aaggctcctc ttactatggg
    16801 agttttaaga cctttaaaac ttattataac taattaccca gaagataaga ttgagatgct
    16861 tgaaatagag aataatgcta aagatgaatc tcaaggaaag agattagttc ctttctctag
    16921 agaattgtat atagaacaag atgattttat ggaagaacct gttaagaaat attttagatt
    16981 tttcccagga aatgaagtcc gtttaaaagg tgcttatttt gtaaaatgta ctgatgtaat
    17041 taaggatgaa aatggaaatg tagttgaaat acatggtact tatgaccctg aaactaagag
    17101 tggctctggc tttacaggac gtaaggtaaa atctacaata cattgggttg atgctaaatc
    17161 agctatacca tgtgaattta gattatttga accattaatt cttgatgata tacctgaaaa
    17221 tgaaggtaaa catttcttag aacaaataaa tcctaattca ttggaaatat tacaaggttt
    17281 tgttgaacct acacagataa aagattctaa accttttgat aaattccaat ttgttagaaa
    17341 tggattcttt agtatagata ataaatatac aactgacgaa aaatttgtat ttaatagaat
    17401 agttcctcta aaaagttctt ttaaaccagg taaataatct tacaatcaaa aaatgaagac
    17461 ttaaaatata aattacttct actataaata aacttagtta gaagtaattt tttatttgag
    17521 tcttcatcat ttactttaaa tgattaactt ttttcactac agattcccat aacttctatt
    17581 ccatctttta tgcattctat gttaagagga aaatctggtc ctttttctcc gtcaatatct
    17641 gttataagtg aatcttcaca ttctatatgc acctttttag ttttaaagta tagtatttca
    17701 tttccattat attgatctaa ataatcacct ctaagcacac ttatcaaaac tggtattgat
    17761 tttggtattg gcattccttt aaaaataatt acatccaaat atccatcatc tatttcagcc
    17821 ttatatgcta gatttatatt tcctgctgtt ttgccattaa aaatcaacat aagatacata
    17881 tctccatcat aatacatttc ctcagaagat acttttatct taaatttcct catatacaat
    17941 gcttcttcta ttccctttat ataataagaa attcttccaa atgaattttt taagtctgtg
    18001 tttatccttt gtgatacatc tgtaaacata ccagcacttg caacatttat aaagtactta
    18061 ttattgactt tccctatgtc tattttcttt ggttttgaat ttatgatttc atttatagct
    18121 tcttttatat caaatgaaat ttgaagagca tttgaaaaat catttgcagt tcctgtaggc
    18181 aaaattccaa ttggaatttt tatgtctaat tctttcattg catttactac taaatctaca
    18241 gtaccatctc caccagctat caatatgtgt tcataagaac tatcaacttc cttaaatgca
    18301 ttctttacag gttctttaat agttaatcta tagggtatca ataaataatt tttttcttga
    18361 tataattcta tgatagtgtc taaatttgat aatatctttt tttcacctga attaggattg
    18421 tatataagtt ttactttttt cattatttct ccttactcat tttattcttt tagtatccaa
    18481 aatcttcatt taaaaaaatc acatgtattc tttctggtgt taattgtctt tttataagtg
    18541 tataactaca gcatattctt cctggacttg aacagtctat acatatacca gtagtcttac
    18601 atccagtatt tgtacttaat cttttacaat tggctggagc agctattgtt tttgttcttt
    18661 ttatagcttc atctacatct ttaactattt tatttactcc tgctataact attactttat
    18721 caggtccata tatcatagca gcaactctat tcccattccc atctaaattg taaagttctt
    18781 catcctctgt tatcgcatta gtacttgtaa aataagcatc tgcagaaaat gactttctat
    18841 atatttcttt catttcttct ggtttgatat cttttgcata tctatcaaga aaattatatt
    18901 tttctcttat aaaatcaatc actcctgttt caaataaggt catagaacct ccacatccta
    18961 ctagagaacc tactttaact atttcttcaa tttttttaag aagctcttct ttgttactta
    19021 ctaaataccc tttcatatta ttgttttcca gagattttat tgttttttct attctttttt
    19081 cattaagcca atttaaattt tgatccattt taacttcccc cttattttta atatgtactt
    19141 aattatttat aaactttatt gtctttataa gtttatttta gtacatctaa aaaaaaatac
    19201 aatataaaac ttaaatagtt ttatataatt ttttccaaaa taacttactc aatcaaaaaa
    19261 ggaaagtaga tgtactattc tactttccct atattgtatg tagtatttat tgcctaaaat
    19321 ctatatatta attatatgtt tcatattata taatatcaca gttaattaaa atgtaatact
    19381 atcttctttt taaacatata aattgtatta ttaaatttaa tatatccaac ttcaataaat
    19441 cttattaatt tgatgaagaa gatgctatag ctgcacttgt tgctgccatt acacatgcaa
    19501 tttgaatagc aacaacaata tttaaaaata tattattagt tatagagcct atattattct
    19561 catttcgtat caaatctgca taaattgaag ctacaatagc agaactaatc attactctat
    19621 tactttttcc taaagaccaa tttccaaagc ctttttcttc tttaagttta tttgaaacat
    19681 tttttatctc ttctattatt tcatcttctc tataatctaa taatgaaatt gctcctatta
    19741 ttggatatcc ataataattc attttacaat cattttcttt aaatgctttt ttaagttcaa
    19801 tagtcttttt acatttaagc atagttctat catcactaaa taaaagaatt tgggataatg
    19861 cttgtaaatc atttccttta taaaaaccat tttcatttag aaattcataa catttttcta
    19921 tgtattctaa atcttcatct aaattttttg aatgaattgc aataagtgct atattacaat
    19981 agtcatcact agaagttaga aatggatgtt ttttcctcat gtaatcatat attattttca
    20041 tttttgatat acatgtaaga taatccattt tctctctatt ttcataaact attgatgctg
    20101 taagtggtaa atatgtatcg ccccaaaact tttcactttt aagttctttg tatatatcta
    20161 aaatcatctt aaaactactt tctggatttg attcaaacga aagtagtgtt gccatataaa
    20221 acatattata tcctctaaaa ttagagaata atccagtatt ttttttaata agctctattc
    20281 gttcttccac taatctagga cttattctct tgttcttaag agtaaatgca agtgcacaac
    20341 tatgttgtat caatcccatt tgccaagaac ctttaacttc atttaatgct ttgtaatttt
    20401 ctattaataa gtttactttt ccatttataa acgattgttc catattgccc tcctagtaat
    20461 atatctcatt gtactaatag ttttatattt attatatata tattaaatac tacaatcaat
    20521 acatattact tcaaagaaca tcattcttca acaataatgt agcctttttt gtaatgtctt
    20581 cccatattat tgactctatc atagtactct gattcacttt cattactcca tttgggcaca
    20641 aatacatcta ttgcattaga attactaaaa tacttactag accccctatc cataacagtt
    20701 tttaattttc catctacaat aatcttagtt ccaaaactca agtgattgtt tgctacaaaa
    20761 ccatcttcta aatcatctcc tgtagcagtt atcgctccat atccattttc ttgattaaga
    20821 cttgtgtaat aactaacttc aaaagttata ggtactaact tctttatttt aatacctaac
    20881 tgattttgta gtttctcctt ttgtactttc aacttatact catcactatt tttataatct
    20941 tccatacctt gattatactt ggaattaaag cttttacctg actttactat agtatctata
    21001 tttactatag attctttaca atgatctgca tctatttttg tttctccatt taccaataat
    21061 ggagttaaac atacactaca tacaacacat gtaatcaatg cttctttaag cttcataaat
    21121 tcccccctta ttattttgat atattagcat atttaatatt atatgtctat atttagattt
    21181 aaataccaca cccatttgct ttaagaagtt gtcttatatt taattcacct taaacactta
    21241 taaatcctct atcttagaat catatagaat aaagctttta tcgttaaata ttttttatta
    21301 atcttttaaa atctaaagct actttattta attttctctt ttttagaatt taagaattaa
    21361 aattctataa ttttaaaaca tattgaattt atttttttga gatgatataa ttttcttaag
    21421 aggtggttga tatgataaaa aatacaaaac aaattacagt agaagttaat gaaattttat
    21481 tacaagaaat atctaagata actaatgacg aaaataatat tttgacagat ttgataaatg
    21541 aatcaattgt aaattatatt cttgaaaaca aaaaacataa cattgaaaat aaagatttag
    21601 aagaagtgat taaattttac aaaaaagaaa atactgaaaa acctaaaagt gcagcaagag
    21661 ctatagctga agcaaaaact cataccctgt attaatcaaa taaaaaagtt cctaaaaact
    21721 aggaactttt ttatattaat aattattaat atatctcaat atttatctca aatttatcaa
    21781 tataagcatg tttaatacaa tctattgtat acttatctta ccctagaaat aatcaaaaca
    21841 aaaattatgc cctttatatc taacaattaa tttacatgat taatatacaa aaattctgac
    21901 ttttaaattc gtatacaata tcaaactaaa ataatactaa tgacaaaccc aatataaatt
    21961 aaattcaaac aggtttgatt ttacatcaaa cttattgtat taatattaaa taacaagaca
    22021 aaatatttat aaaaattaca aattt
//
LOCUS       DAEQJM010000058        21930 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.058, whole genome shotgun sequence.
ACCESSION   DAEQJM010000058 DAEQJM010000000
VERSION     DAEQJM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21930
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.058"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            358..669
                     /gene="rpsJ"
                     /locus_tag="KRQ43_002771"
     CDS             358..669
                     /gene="rpsJ"
                     /locus_tag="KRQ43_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBH2743116.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            761..1390
                     /gene="rplC"
                     /locus_tag="KRQ43_002772"
     CDS             761..1390
                     /gene="rplC"
                     /locus_tag="KRQ43_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBH2743117.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1420..2043
                     /gene="rplD"
                     /locus_tag="KRQ43_002773"
     CDS             1420..2043
                     /gene="rplD"
                     /locus_tag="KRQ43_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBH2743118.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2043..2333
                     /gene="rplW"
                     /locus_tag="KRQ43_002774"
     CDS             2043..2333
                     /gene="rplW"
                     /locus_tag="KRQ43_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBH2743119.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTASFKKAVVKLTADSKEIEFFQGM"
     gene            2363..3193
                     /gene="rplB"
                     /locus_tag="KRQ43_002775"
     CDS             2363..3193
                     /gene="rplB"
                     /locus_tag="KRQ43_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBH2743120.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3228..3509
                     /gene="rpsS"
                     /locus_tag="KRQ43_002776"
     CDS             3228..3509
                     /gene="rpsS"
                     /locus_tag="KRQ43_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBH2743121.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3541..3876
                     /gene="rplV"
                     /locus_tag="KRQ43_002777"
     CDS             3541..3876
                     /gene="rplV"
                     /locus_tag="KRQ43_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBH2743122.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3899..4714
                     /gene="rpsC"
                     /locus_tag="KRQ43_002778"
     CDS             3899..4714
                     /gene="rpsC"
                     /locus_tag="KRQ43_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBH2743123.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4750..5181
                     /gene="rplP"
                     /locus_tag="KRQ43_002779"
     CDS             4750..5181
                     /gene="rplP"
                     /locus_tag="KRQ43_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBH2743124.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5183..5386
                     /gene="rpmC"
                     /locus_tag="KRQ43_002780"
     CDS             5183..5386
                     /gene="rpmC"
                     /locus_tag="KRQ43_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBH2743125.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5410..5664
                     /gene="rpsQ"
                     /locus_tag="KRQ43_002781"
     CDS             5410..5664
                     /gene="rpsQ"
                     /locus_tag="KRQ43_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBH2743126.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5690..6058
                     /gene="rplN"
                     /locus_tag="KRQ43_002782"
     CDS             5690..6058
                     /gene="rplN"
                     /locus_tag="KRQ43_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBH2743127.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6082..6387
                     /gene="rplX"
                     /locus_tag="KRQ43_002783"
     CDS             6082..6387
                     /gene="rplX"
                     /locus_tag="KRQ43_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBH2743128.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6417..6959
                     /gene="rplE"
                     /locus_tag="KRQ43_002784"
     CDS             6417..6959
                     /gene="rplE"
                     /locus_tag="KRQ43_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBH2743129.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6977..7162
                     /locus_tag="KRQ43_002785"
     CDS             6977..7162
                     /locus_tag="KRQ43_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBH2743130.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7195..7593
                     /gene="rpsH"
                     /locus_tag="KRQ43_002786"
     CDS             7195..7593
                     /gene="rpsH"
                     /locus_tag="KRQ43_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBH2743131.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7624..8166
                     /gene="rplF"
                     /locus_tag="KRQ43_002787"
     CDS             7624..8166
                     /gene="rplF"
                     /locus_tag="KRQ43_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBH2743132.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8202..8570
                     /gene="rplR"
                     /locus_tag="KRQ43_002788"
     CDS             8202..8570
                     /gene="rplR"
                     /locus_tag="KRQ43_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBH2743133.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8591..9100
                     /gene="rpsE"
                     /locus_tag="KRQ43_002789"
     CDS             8591..9100
                     /gene="rpsE"
                     /locus_tag="KRQ43_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBH2743134.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9115..9300
                     /gene="rpmD"
                     /locus_tag="KRQ43_002790"
     CDS             9115..9300
                     /gene="rpmD"
                     /locus_tag="KRQ43_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBH2743135.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9333..9776
                     /gene="rplO"
                     /locus_tag="KRQ43_002791"
     CDS             9333..9776
                     /gene="rplO"
                     /locus_tag="KRQ43_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBH2743136.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9820..11088
                     /gene="secY"
                     /locus_tag="KRQ43_002792"
     CDS             9820..11088
                     /gene="secY"
                     /locus_tag="KRQ43_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBH2743137.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11105..11755
                     /locus_tag="KRQ43_002793"
     CDS             11105..11755
                     /locus_tag="KRQ43_002793"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBH2743138.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11756..12502
                     /gene="map"
                     /locus_tag="KRQ43_002794"
     CDS             11756..12502
                     /gene="map"
                     /locus_tag="KRQ43_002794"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBH2743139.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12524..12793
                     /locus_tag="KRQ43_002795"
     CDS             12524..12793
                     /locus_tag="KRQ43_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HBH2743140.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYDFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12831..13049
                     /gene="infA"
                     /locus_tag="KRQ43_002796"
     CDS             12831..13049
                     /gene="infA"
                     /locus_tag="KRQ43_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBH2743141.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13085..13198
                     /gene="rpmJ"
                     /locus_tag="KRQ43_002797"
     CDS             13085..13198
                     /gene="rpmJ"
                     /locus_tag="KRQ43_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBH2743142.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13351..13722
                     /gene="rpsM"
                     /locus_tag="KRQ43_002798"
     CDS             13351..13722
                     /gene="rpsM"
                     /locus_tag="KRQ43_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBH2743143.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13758..14156
                     /gene="rpsK"
                     /locus_tag="KRQ43_002799"
     CDS             13758..14156
                     /gene="rpsK"
                     /locus_tag="KRQ43_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBH2743144.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14188..14811
                     /gene="rpsD"
                     /locus_tag="KRQ43_002800"
     CDS             14188..14811
                     /gene="rpsD"
                     /locus_tag="KRQ43_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBH2743145.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14889..15836
                     /locus_tag="KRQ43_002801"
     CDS             14889..15836
                     /locus_tag="KRQ43_002801"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBH2743146.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15857..16198
                     /gene="rplQ"
                     /locus_tag="KRQ43_002802"
     CDS             15857..16198
                     /gene="rplQ"
                     /locus_tag="KRQ43_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBH2743147.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16318..17151
                     /locus_tag="KRQ43_002803"
     CDS             16318..17151
                     /locus_tag="KRQ43_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH2743148.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17139..18005
                     /locus_tag="KRQ43_002804"
     CDS             17139..18005
                     /locus_tag="KRQ43_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH2743149.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDISFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            17999..18802
                     /locus_tag="KRQ43_002805"
     CDS             17999..18802
                     /locus_tag="KRQ43_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBH2743150.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18834..19565
                     /gene="truA"
                     /locus_tag="KRQ43_002806"
     CDS             18834..19565
                     /gene="truA"
                     /locus_tag="KRQ43_002806"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH2743151.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19685..20116
                     /gene="rplM"
                     /locus_tag="KRQ43_002807"
     CDS             19685..20116
                     /gene="rplM"
                     /locus_tag="KRQ43_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBH2743152.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20145..20537
                     /gene="rpsI"
                     /locus_tag="KRQ43_002808"
     CDS             20145..20537
                     /gene="rpsI"
                     /locus_tag="KRQ43_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBH2743153.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            20996..21748
                     /gene="cwlD"
                     /locus_tag="KRQ43_002809"
     CDS             20996..21748
                     /gene="cwlD"
                     /locus_tag="KRQ43_002809"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HBH2743154.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8806 a         2559 c         4501 g         6064 t
ORIGIN      
        1 atggatttaa tataaaaaaa agaggggggt aactcctctc ttttttgttt tttgttgaca
       61 agtagcgcta aagcatatat actaaactag tgccttgaga cagattaaca atcaagttta
      121 aggttatgat gttgtaatag aaaataaaat tgaaaaaaac agaaaaaaaa cttgaaaaaa
      181 tgtaacagat gatataaaat ataatagtgt gcttgagaga ttaagaaaat aataattaaa
      241 tcctagtgaa atacgaactg atatcgattt aaaagttaca acacacccgg agcagtgtat
      301 cggtattggt tgtacgcaac ttgaaaatta aacacgtgat aaaggaggga aaacaaaatg
      361 gctaagaatg aaaaaataag aataagatta aaatcatatg atcacaaatt attagatttt
      421 tcagcaggta aaatagttga aactgctaaa aaggctggat cacaagtttc aggacctgtg
      481 cctctaccaa cagaaaaaca agttgtaact atattaagag ctgtacataa gtacaaagac
      541 tctagagaac aatttgaaat aagaactcat aaaagactaa tcgacatagc taatccaaca
      601 cctaagacag ttgactcatt aatgagatta gacttaccag caggtgtaga tatagaaata
      661 aaattataag aacccctaag atattatcct atagatgatt atcttagaat gattactcta
      721 aaagatgtaa tccgctgtaa gaattatagg aggtgctaat atgaaaggaa tattaggcaa
      781 aaaagttggt atgactcaaa tattcactga taaaggtgta gttatacctg taacagctgt
      841 tgaagcaggg cctatggtcg ttactcaaat aaaaacagtt gataaagatg gatacaatgc
      901 tatacaaata ggttttgaag atgctaaaga aaaagcttta aacaaaccta aaaaaggaca
      961 tttagctgct gctaatgttt taaagaaaca tttaaaagaa tttagagtag attctgtaga
     1021 aggatacaca gtaggacaag aaataaaagc tgatgtattt gaagcaggtg caaaaataga
     1081 tgttactgga ataagtaaag gtaagggatt ccaaggtcca ataaaaagac atggacaaag
     1141 tagaggtcct gaaactcatg gttctagata ccacagaaga ccaggttcaa tgggagcttg
     1201 ttcttaccca ggtagagtat ttaaaaacaa aaaattagct ggacatatgg gaagcgtaaa
     1261 ggtaacagtt caaaacttag aggttgttaa agtagatgct gacaagaacc ttatattagt
     1321 taaaggagct ataccaggag ctaaaggttc agtagtaact ataaaagaag ctataaaggt
     1381 ttctaaataa tgactaacct agagaaagga ggaataacaa tgccaaaatt aaatgtacta
     1441 aatgttagtg gacaaaacgt tggagaaata gaattatcag attctatatt tggcgtagaa
     1501 gttaatggac atgttttata cgaagttgta aaaaatcaat tagcaaataa gagacaagga
     1561 actcaatctg ctaaaactag agcagaagtt agaggtggcg gaagaaaacc ttggaaacaa
     1621 aaaggaacag gtagagcaag acaaggttct acaagatctg tacaatgggt aggtggagga
     1681 gttgcttttg cacctaaacc aagaagctac aaatatacat tacctaagaa ggtaagaaga
     1741 ttagctatga agagtgcttt atcttcaaaa gttcaaaata gtgaagttat agtattagat
     1801 gcattaaaca tggatgctcc taagactaaa gaatttgctc aaatattaaa caatataaat
     1861 gctgctaaaa aagctttagt agttatagct gacaaaaacg ataacgtaat aaaatcagct
     1921 agaaatatag aaggtgttca aactgcatta gttaatacta tgaatgtata tgatatatta
     1981 aaatacgatt catttataat aactacagat gctgttaaaa aagtggagga ggtgtacgca
     2041 taatgactaa tccacatgat gtaataataa gaccagttgt aactgagcac agtatggctg
     2101 aaatgggtga aaaaaaatac acttttgttg tggctaaaga tgcgaacaaa actgaaataa
     2161 aaaaagcagt agaaaaagta ttcggagtta gtgttgataa agtaaatact ttaaactacg
     2221 atggaaaagt taaaagaatg ggtagaactc aaggaagaac agcaagcttt aagaaagcag
     2281 tagttaaatt aactgctgat agtaaagaaa tagaattctt ccaaggaatg tagtattata
     2341 acaaacgaag gagggaaaac agatggctat aaaaaagttt agaccaactt ctcctgcctt
     2401 aagacaaatg acagttttag tttctgatga aataacatgt aatcaaccag aaaaatctct
     2461 tttagttaac ttaaagaaaa atgctggtag aaacgtacat ggtagaataa ctgttcgtca
     2521 tagaggtgga ggacaaaaaa gaaaatatag aataatagat tttaaaagag ataaagatgg
     2581 tatacctgct aaggttgcta ctatagaata tgatccaaac agaactgcaa atatcgcatt
     2641 attaaactat gctgatggag aaaaaagata tatattagct ccagttggaa ttaacgttgg
     2701 agatactata ttatcaggat taggtgctga tataaaacca ggaaactgtt tagcattaaa
     2761 agatatgcca gttggtacta tcattcataa tatagaatta aagccaggaa aaggagctca
     2821 attagttaga tctgctggag tttctgcaca attaatggct aaagaaggaa aaaatgcttt
     2881 attaagatta ccatcaggtg agatgagatt agtaagcata aactgtaaag ctactatagg
     2941 tcaagttgga aatatagagc atggtaacgt agttatcggt aaagcaggta gaaaaagaca
     3001 tatgggaata agacctactg taagaggttc tgtaatgaac cctaatgacc atccacacgg
     3061 tggaggggaa ggtagatctc caataggtag accatctcct gttactccat ggggtaaacc
     3121 agctcttgga tacaaaacta gaaagaaaaa taaagcttca aataaactaa tagtatcaag
     3181 aagaactaag tagtaaattt atttttgctc ggaaaggagg aatataaatg tcaagatcaa
     3241 ctaaaaaagg gccttttgtc catgcaagac ttttaaagaa gatagaagct atgaatgcta
     3301 gtggaaataa agaagttata aaaacttggt caagatcttc aactgtattt ccacaaatgg
     3361 tagaaaacac tatagctgtt catgatggaa gaaaacatgt tccagtatat ataacagaag
     3421 atatggttgg acataaatta ggtgagttcg ttcctactag aactttcaaa ggacataagg
     3481 atgacgaaaa atctaataag agaaaataat taaattatga ctaagaaagg aggaataaca
     3541 atggaagcaa aagctactgc taaatacgta cgtgtatcac caagaaaagc aggccaaata
     3601 tgtgaccttg ttagaggaaa gaatgttgat gaagcattag caatattaaa gtttactcca
     3661 agaggagcag cttcaataat agctaaggtt gtaaaatcag ctaaagctaa cgcagaaaac
     3721 aatcacgaaa tggatactga aaaattatat atagcatcaa tagttgctaa tcaaggacca
     3781 acaatgaaga gattcatgcc tagagctatg ggtcgtgcaa ctacaataag aaaaagaact
     3841 tctcatatag aggttgttgt taaagaaaaa aaataattaa tagataggag ggaaagtaat
     3901 gggtcaaaag gttaatccac acggcttaag ggtcggtgtt ataaaagatt gggactcaag
     3961 atggttcgct actgataaaa aagagttcgg aaacttatta ttagaagacc ataatatacg
     4021 taaattctta aagaaaagat tatactcagc tggagttgct aagatagaaa tagaaagatc
     4081 agctaacaaa ataaaaatgg acttacacgt tgctaagcct ggtgtagtta taggaagagc
     4141 tggtgcagga atcgaagcat taaaagctga attagaaaaa atgacaaaga aaactataat
     4201 agttaatata gtagaagtaa gaagtacaga taaaaatgct caattagtag ctgaaaatat
     4261 agctttagct atagagagaa gggttgcttt cagaagagca atgaaacaag ctatacaaag
     4321 agcaatgaaa tctggtgcta aagggataaa agtttctgct tcaggaagat taggtggagc
     4381 tgaaatggct agaactgaag gttatagtga aggaaatgtg ccactacaaa ctttaagagc
     4441 agatatagat tatggtttcg ctgaagctga tacaacttat ggaaaaatcg gtataaaagt
     4501 ttggatatgt aatggtgaag ttttaccaac tagagacggt gtaaatccaa gagaagaaag
     4561 cagaaagagc gatagaagag acaacaagag agataataga agaaacgata gaagaggaaa
     4621 tgacagaaga ggaaatgata acagaggaaa ctacagagga caaagacctc aaggtggatc
     4681 aagacctcaa agaactgaaa acaaaggaaa ttaataatag ttaggttcaa ggaaggagga
     4741 aaaatactca tgttaatgcc aaaaagagta aagcgtcgta gagttcatag aggaagcatg
     4801 gctgggcaag ctcataaggg taataaagtt acttatggtg agtttggatt agtagcatta
     4861 gaagcttctt ggataacttc taatcaaata gaagctgcca gaatcgcgat gactagatat
     4921 ataaaaagag ggggaaaggt ttggataaaa atattccctc ataaaccagt aacaagaaaa
     4981 ccagcagaga ctcgtatggg tgcagggaaa ggttctccag aatattgggt agctgtagtt
     5041 aagccaggaa gagttatgtt tgaattagca ggtgtttctg aagataaagc aagagaagct
     5101 atgagacttg ctgcacataa attaccaatc aaatgtaaat ttgttaaaaa agaagattta
     5161 gaagtaaagg gtggtgaata ggatgaaagc taaagaatta agagatttaa caagcgaaga
     5221 gctaatgaac aaattaaacg acttcaaaag tgaattattt agcttaagat tccaattagc
     5281 tactggtcaa ttagaaaata cagctagaat aaagtttgtt aagaaggata tagcaaaagt
     5341 taaaactgtt cttgctgaaa gaaagttata cgaaactaga gcttaatttg gaaaggaggc
     5401 tttttaaaca tggaaagagg aagaagaaaa gttagaatag gccgtgttgt tagtgataag
     5461 atggataaaa caatagtagt agctgttgaa gaattcgtac gtcatccact atataataaa
     5521 cgtgttaaga gaactaagaa attcaaggct catgatgaaa agaatatatg taacatcgga
     5581 gatagagtta aaataatgga aactagacca ttatctaaag ataagagatt cagactagtt
     5641 gaagttgttg agaaagttaa gtagtttttg aagaaggagg gattacgata tgatacaaca
     5701 agaatcacgt ctaagagttg ctgataactc aggagctaaa gaacttttat gtatacgtgt
     5761 tctaggcgga agtaaaagaa gatatggtaa cataggcgac gttatagttg ctactgttaa
     5821 aagtgcaaca cctggtggag ttgtaaaaaa aggtaaggtt gttaaagctg ttatagtaag
     5881 aagcaaacaa ggcgtaagac gtaatgacgg aagctatata tcttttgatg aaaatgctgc
     5941 tgttataata aaggacgata aaactccagt aggaactcgt atattcgggc ctgttgctag
     6001 agagttaaga gacaatgaat tcatgaaaat agtttctctt gctccagaag tactataatt
     6061 aaggaggtgc aataggacat gatgcgtgtt aaaaaaggtg acactgttgt agttatagca
     6121 ggtaaagata aaggtaaaaa aggttcagtt ttaaaggtat atcctaaaac tagcaaagtg
     6181 ttagttgaag gtgtaaatgt aataactaaa catcaaaaac caagtgctat gaaccaacaa
     6241 ggtggaataa taaataaaga agccccaata cacatatcta atgtaatgcc atttgatcct
     6301 gaaacaggaa aaggcgttag agtaagatat gaagtaaaag atgggaacaa agtaagagta
     6361 tcagcaaaga gcggaaaaga attataataa atattgcttg aaaggaggga ccttaaatgg
     6421 cttctagatt acaagaaaaa tacatgaaag aagttgctcc tgctttaatg gagaaatttg
     6481 gatacaaaaa cgtaatggag atacctaagt taaataaaat agttattaac atgggtatag
     6541 gtgacgctag agaaaatcca aaaggattag aaaaaggcgt tgaagaatta gaaatgatat
     6601 caggacaaaa gcctgttata actaaagcta gaaaatctgt tgctaacttc aaattaagag
     6661 aaggaatgcc aataggaaca aaagttacat taagagctga caaaatgttc tactttatgg
     6721 acaaattagt ttcagtttct ttaccaagag ttagagattt tagaggagtt aaccctaatg
     6781 cttttgatgg tagaggaaat tatgctttag gagttaaaga acaattaata ttccctgaaa
     6841 tagaatatga taaaatagat aaagtaagag gaatggatat aatatttgtt actacagcaa
     6901 aaactgacga agaagctcgt gaattattaa aattattagg aatgccattt tctaagtaag
     6961 caaaggaggg attcccgtgg ctagaaaagc gatggttgtt aagcaacaaa gaaagcaaaa
     7021 gtacgctact agagaataca ctagatgtac tatatgcgga agaccgcatt cagttttgaa
     7081 aaaatttggt atatgccgta tatgctttag agaattagct tataaaggtc aaatacctgg
     7141 tgttagaaaa gcaagctggt agaagcttga ttagaatgga aggagggcaa caaaatgaca
     7201 atgacagatc caattgcaga tatgcttact cgtataagaa atgctaatgt tgttaagcat
     7261 gaaactgtag atgttccagc ttctaatatg aagaaagaat tagctagaat cttattagaa
     7321 gaaggtttca taagaggtta tgatgttata gaagatggaa aacaaggtat cataagaata
     7381 caattaaagt acggacaaga aggcgaaaga gttataacag gtcttaagaa aatatctaag
     7441 cctggaatga gagtttacgc tgctaaccat gagataccaa aagtattaaa cggattagga
     7501 atatcagtta tatctacttc aaaaggaata ttaactgaca agcaagctag aaaagaaaat
     7561 gttggtggag aagtaatctg ctacgtttgg taattaatat gaacaatgta aggaggtgcg
     7621 accatgtcaa gaataggtgt taagccaata ataataccag caggtgttga agttactata
     7681 gctgaaggaa atttagttac agtaaaaggt ccaaaaggaa ctttaactaa acaattaagt
     7741 gctgagttaa acataaaaaa agaagaaaat acaataatgg ttgaaagacc aactgataat
     7801 aaaaaacata gatctttaca cggactaact agaactttat tagataatat ggttgtaggt
     7861 gtaaatactg gtttcgaaaa gaaattagaa ttaaaaggtg ttggatatag agctcaaaaa
     7921 caaggaaaga aattagttat gaacttaggt ttctctcatc cagttgagat ggaagatcca
     7981 gaaggaataa ctgttgaagc tccaaaccaa acagagttaa tagtaaaagg tatagacaag
     8041 caattagtag ggaattatgc tgctaagata agagcttgga gaaagccaga gccatacaaa
     8101 ggtaaaggta taaaatacgt tgatgaagta atcagacgta aagaaggaaa aactggtaaa
     8161 aaataatacc aaaacttaaa cgctagaaag gagtgagcta ggtgttaaaa aaggctgata
     8221 aaaatgctaa tagacttcaa agacataaga gagttcgtag aaaaataagc ggtacttctc
     8281 aaagaccaag attatgtgta tttagaagtg ctaacaatat atatgctcaa ataatagatg
     8341 acacaaaaag agtaactcta gttgctgcat cttctttaga agcagaagtt aagagtgctg
     8401 tcaatcatac aggaaacaag gaagcagcta agaaagttgg agaattagtt gctaaaaaag
     8461 ctgttgaaaa aggaatcact gaagttgtat ttgacagagg tggatactta tatcatggaa
     8521 gaattcaaga attagctgaa ggtgctagag aagctggtct taagttctaa tacgaaggag
     8581 ggaaaaatac atgctacgtc gtaagccgat agatgcagga caacttgact tacaagaaaa
     8641 agttgttgaa gtaagacgtg ttactaaggt tgtaaaaggt ggtagaaatt tcagatttgc
     8701 agcattagta gttgttggag atgaaaacgg acacgttggt ataggtgctg ggaaagcaat
     8761 ggaagtacca gacgctataa aaaaagcagt tgaagatgct aagaaaaatc taatagtagt
     8821 gccaatagtt gggactacaa ttcctcacga agtacgcgga cactttggtg ctggaaatat
     8881 attaataatg cctgctgtag aaggtacagg agtaatagct gggggacctg ctagagccgt
     8941 acttgagcta gctggactaa aagacgttag agctaaatct ttagggtcta acaatccaag
     9001 aaatatggta aatgctacaa tagaaggact taattctcta aaaacagttg aagatatagc
     9061 taaacttaga ggtaaaaaag ttgaagaact tctagggtaa ggaggtagtg taaaatggct
     9121 aaattacaaa taaagttagt tagaagtgtt ataggaacta ctcctaacca aaaaaagaat
     9181 gttgaagcgt taggattaag aaaaagagaa caagttgttg taaaagaaga caatgctcaa
     9241 acaagaggta tgataaataa agtaagtcac ttattagaag taactgaaat agctgaataa
     9301 tttttataaa gtagtgcaag gaggtgcaat ccatgaagtt acatgagtta aaacctgctg
     9361 aaggtgcagt aagagctaag agaagattag gtagaggtac tgcaactgga caaggtaaaa
     9421 ctgcaggacg tggacaaaaa ggtcaatggt ctcgttctgg tggtggagta agagtaggat
     9481 ttgaaggtgg acaaatgcca ctagctagaa gacttcctaa gagaggtttc aataacatat
     9541 ttaagaaagt ttacacagaa gttaatgttg aagttttaaa cagatttgaa aatggaacag
     9601 aaataactgc agaattatta aaatctacta aaactataag caaaataggt aaagacggaa
     9661 ttaaaatctt aggtgaaggt aatttagaga aagctttaac tgttaaagct gctaaattta
     9721 cagcttcagc tcaagaaaaa atagaaaaag ctggtggaaa agcagagtta gtataataac
     9781 ctgctaatct cctagccagt acaggcgggg tgaattagcg tgctgtcaaa attaaaacaa
     9841 gcttggaaga ttaaagcagt aagaaaaaaa gtaatgtata cacttatgat gatcgtgata
     9901 ttcagaatag gtactactat accagttcca ggcatagaca ctagtattat acaaaagatg
     9961 gtaggcggca atagtctact ttctctgtat aatatgttta ctggtggagc atttagtaac
    10021 ttttcactat ttgctttagg tataagtcca tatatcactg catcaatcat aatacaactt
    10081 ctaacagtag gttttgaaag tttagcagaa cttcaaaaat ctggtgaaga aggaaagaaa
    10141 aaaatcaata agtacactaa atatacagca ctagctctag cagttgtaca agctttggga
    10201 attacattag gaattgtaag aagtgcttta atatcaaata gtgtgttttt tatcacaact
    10261 gttgtaataa cattagtttc agcaagtatg ttagtaatgt ggattgggga caaaattact
    10321 gaaaaaggaa tcggtaatgg tagttcagta ataatatttg caggtataat atcaagaata
    10381 cctacagatg ttattaaaat atcgcaacaa gttaaatctg gcgaagttgc accttgggtt
    10441 atagtgattc tagctgtagt tatattactt acagtaacag gagttacatt tatacaagaa
    10501 gcaactagaa agatacctgt acaatatgct aaaagagttg ttggaagaaa aatgtatgga
    10561 ggacaaagtt ctcatatacc aatgaaagtt aaccagtcag gagttatgcc tataattttt
    10621 gctagttcac ttttagcttt ccctcaaaca atagctatgt ttatgggtcc aaatgctcag
    10681 gcttttgttc aaaaatactt aagtatggca acagaacaag gattttggac atatagatca
    10741 attgagattc tacttataat tttcttctca tatttttata caactgtatc atttaataca
    10801 gaagacatat ctaaaaatat gaaaaataat ggtggattta taccaggtat aagaccaggt
    10861 gagcctacta tggattattt aaatagaatt ttaactagat taactttagc tggagctact
    10921 ttcttagcaa taattgctat ggtgccagct cttacaacac attatatgaa agtaaatatg
    10981 agtctagctg ggacttcatt gctaatcgtt gttggagttg ctttggagct taagagacag
    11041 ttagagtcaa acttagttat gagaagctat caaggtttct taaaataaaa tggagatgga
    11101 taatatgaga ataatattac ttggacctcc aggtgctggt aaaggtactc aggcggcagg
    11161 aatagtagaa aaatacaata tacctcatat atcaacagga gatatattca gaaagaatat
    11221 aaaagaggga acagaacttg gaaaaaaagc taaagaatac atggaccaag gtttattagt
    11281 accagatgag ttaactgtag gtttagttac tgatagaata tctcaagaag attgtaaaaa
    11341 tggatttatg ttagatggat ttccaagaaa tgtagcacaa ggagaacatt tagatatctt
    11401 cttaaaaaat gctggtatat cactagataa agttgtcaat attgaagttg ataagagtat
    11461 attagtgtct agagcagttg gtagaagaat atgtaagtct tgtggagcta cttaccatgt
    11521 tgagtttaat cctcctaaag tagaaggtgt atgtgatgta tgccaaggag aattatatca
    11581 aagagctgat gataatgaag aaactgtatc taagagaata caagtttatc tagatgaaac
    11641 taagccttta gtagattatt atagcaaaca aggtataata gcagatataa aaggtgatca
    11701 agcaatagat aaagtatttg aagatattgt cgcagcctta ggaagtggaa aataaatgat
    11761 tatcttgaaa tcaaaaaaag aaatagaact tttaagagaa gcaggtaaaa tagttgctga
    11821 cactcatgaa gttttaagaa aagctatttc tccgggaata tctactttag aattagataa
    11881 aatagctgaa gagaatataa gaaaatacaa tgcagagcct tcttttaaag gatatggagg
    11941 ttttccagga agtatatgtg cttctatcaa tagagaggta gtacatggta ttccaggaga
    12001 aactatatta caagaaggtg acattgtaag tttggatata ggagcctatt ataaaggata
    12061 tcatggtgat tctgcgaaaa ctcacggagt aggcatgata tctgaagaag ataggaaatt
    12121 gatagaagta actagagaaa gcttctatga aggaataaaa tttgctaaat taggatatag
    12181 actttcagat atctcacacg cagtacaaac acacgttgag aaacatggtt tctcggtagt
    12241 tagagattta gtgggtcatg gagttggagc aaatcttcat gaagacccac aagtacctaa
    12301 ttatggactc ccaggaaaag gaccaagact tagagaagga atggttattg ctatagagcc
    12361 aatggttaat gcaggtcgtt atcatgtaaa gactctatca gatgggtgga cgactgttac
    12421 aatagatgga aaaaaatcag ctcattatga gcatacgata gcaattactg aacatgaacc
    12481 tttgatattg acaaagttgt aatttaaaaa gtaggtgaaa aaagtgctat cagataattt
    12541 aagtataggt caagttgtta aagtttcatt aggacgagat aaaggaaatt tattctttgt
    12601 agtcaaaata attaataatg aatatgtatt aatagctgat ggaaaaaaga gaaaacttga
    12661 caaacctaag ttaaagaaag tgaagcactt aaaaaaatat gattttatta atgatgaagt
    12721 tagaaaaaga gtagtatctg gacaagagat tacagattct tttttaagag ctgaacttac
    12781 taagttaaat tagataattt aacttattga aatggagggc tggttagtta atggccaaaa
    12841 aagatgttat agaattagaa ggtacagttt cagaagcttt acctaatgct atgttcaaag
    12901 ttaaactaga aaatggacat gagatattat gccacatttc tggaaagcta agaatgaact
    12961 tcataagaat tcttgaaggt gacaaggtga atgttgaact ttctccatat gaccttacaa
    13021 gaggaagaat tacttggcgt aagaagtaga ctatattaat atttagtcta aggagggatt
    13081 aataatgaag gttagaccat cagtaaaacc aatatgtgaa aaatgtaaag taataaaaag
    13141 aaaaggaaaa gtaatggtta tctgtgaaaa tccaaagcat aagcaaaagc aaggataaga
    13201 aattattact agcattttgt taaattttat agtataatac tatattgtga tgttaacaaa
    13261 agaacgttaa aatcgttgaa caatctggcg taggattggc atatgatgtg aagttttaaa
    13321 cactaaaaac tatgtgtagg aggtgcgatc atggcaagaa tagctggggt agatttacct
    13381 agagaaaaaa gagcggagat aggcttaact tatatatatg gtataggtaa agcaactgct
    13441 aacgaaatat tagctaaggc tgagataaat ccagatacta gaataaaaga tttatcagaa
    13501 gatcaagtta atgagttaag aaaagttata gatgacgatt tcttagttga aggtgactta
    13561 agaagagaaa ttgctttaaa cataaagaga ttaagagata taaaatgtta tagaggaata
    13621 agacacgcta aaggtcttcc attaagagga caaagaacta agactaatgc tagaactaga
    13681 aaaggtccta gaaaaacagt atctcgtaaa aagaaaaaat aaataaataa taactagatg
    13741 aaggagggaa aaggaaaatg gctaaaccaa aaaagaaagt tacacgtatt agaagaagag
    13801 aacgtaaaaa tatagaacgt ggtcatgctc atatacaatc aactttcaat aatacaataa
    13861 taactttaac tgacgttcac ggaaatgcta tatcttgggc aagttctgga caattaggat
    13921 tcaaaggatc aagaaaatca actccatttg catctcaaat ggctgctgaa acagctgcaa
    13981 aagctgcgat ggaacacgga ctaaaaagtg ttgaggtatt cgtaaagggg ccaggttcag
    14041 gaagagaagc tgcaataaga gctttacaag caactggact agaagtaact atgataaaag
    14101 acgttactcc aatcccacat aacggatgca gaccaccaaa gagaagaaga gtgtaattaa
    14161 taagagtaca ataggaggtg tagataaatg gcaagatata caggtgcatc atgtagacaa
    14221 tgccgtagag agggaatgaa attattcctt aaaggtgata gatgttatac agacaaatgt
    14281 gctatagtaa aaagaaacta tgctccaggt caacatggcc aaggaagaaa gaaagtttct
    14341 aactatggat tacaattaag agaaaaacaa aaagttaaaa gaatatatgg agttttagag
    14401 actcaattta gaaatttata tgaacgtgct gaaaatatgc ctggtaaagc aggtgagaac
    14461 ttattaagtt tattagagag aagattagat aatgtagttt acagaatggg actagcatct
    14521 tctagaaaag aagctagaca attagtgact catggtcatt tcactttaaa tggaaataaa
    14581 gtagacatac cttcattaat agttaaggtt ggagatgtta tagaagttaa agagaaatca
    14641 agatcttctg caaaattcaa aaatttagta gaagttaact caagaatagc tcctaagtgg
    14701 ttagaagcta atgtagaagg aatgacagca aaagtagttg gtgttccaac aagagaagat
    14761 atagatcttg agatagcaga gcacttaatc atagaacttt actctaaata ataagcacac
    14821 ttttaaaaat tattttaaaa ttttgtttac cctcagtgga ttactgaatt ttaaggaggg
    14881 ttttgtccat gatagaaata gaaaagccaa aagtagatat agttgagctt agcgaagact
    14941 atagatatgg taagtttgtt atagagcctc tagaaagagg atatggaata actataggta
    15001 acgcattaag aagaatatta ttatcatcat taccaggtgt agcagtgaat gctataaaaa
    15061 tcgatggagt tcttcatgaa ttttcaacaa tacctggtgt taaagaagat gttactgaga
    15121 taatattaac tttaaaagag ctttcagcaa ctatagatgg tgaaggaagt agaacactta
    15181 aaatagaagc tcaaggacca tgctctatca caggtgcaga tataatctgt cctccagatg
    15241 ttgaaatatt aagtaaagat ttagcaatag ctacattaga tgataatgct aaacttaata
    15301 tggagatatt tgtagataaa ggtagaggtt atgtttctgc tgaagaaaat aaaacagaga
    15361 atgttccaat aggtgtttta cctgtggatt caatatatac tcctgttgag aaggttagtt
    15421 atcatgtgga aaacacaaga gttggtcaaa aaacagatta tgataaatta gtactagaag
    15481 tttggactaa tggtagtata aatcctcaag agggaatatc attagctgca aaggtattag
    15541 ttgagcattt aaacttattt atagacttaa ctgaacatgt aagtagtgtt gaaatcatgg
    15601 tagaaaaaga agaagatcaa aaagaaaaag ttcttgaaat gactatagaa gaattagatt
    15661 tatcagttag atcatataac tgtttaaaga gagcgggaat taatacagtt gaagaattag
    15721 ctaataaatc tgaggatgat atgatgaagg ttagaaacct aggtaagaag tcattagaag
    15781 aggtaataca aaaactagaa gaacttggat tgggattaaa accaagtgaa gaatagcgag
    15841 caaaggaggg ataagaatgg ctaagtaccg taaattagga cgtgaaacag ctcacagaaa
    15901 ccttatgtta agaaacttag taacttgctt actaagaagt ggaagaatag aaactacagt
    15961 gactagagcg aaagaaactc gtagaatggc tgaaaagatg ataactcttg ctaagagagg
    16021 agatcttcat gctagaagac aagttttagc ttatgttatg gatgaaacag tagttaataa
    16081 cttattcaca gatttagctc caaaatatgc tgagagaaat ggtggataca ctagaataat
    16141 aaaaataggg ccaagaaaag gcgatgctgc tgaaatggct tttatagaat tagtatagta
    16201 aggaaaggat taggcttgat ggcttaatct tttttttatt tttttgacta aggtatgata
    16261 taataatgtg taaaatgatt tttataagtt attgcttact aaaaggagta tgagttaatg
    16321 gataatatag taaaggtaaa taatatttcg tttgagtata ttacagatga agcaaaactt
    16381 aaagcaatag ataatttaag cctagatgtt aaaaaaggag aatttgttgc gataatagga
    16441 cataatggtt ctggtaagtc tactttatct aaaaacttaa atgctattct tatgcctact
    16501 gaaggaaata ttcttattga tgatatggat actaaagaag aagaaagatt atgggatata
    16561 agacaaactg caggcatggt atttcaaaat ccagataatc aaatagttgc tactatagta
    16621 gaagaagacg ttgcatttgg acctgagaac ttaggtatag aaccaaaaga aataagacga
    16681 attgtagagg agtctttaaa aagtgtaggt atgtatgatt taagagatag acagcctcat
    16741 ttgttatcag gaggtcaaaa gcaaagagtt gcaatagcag gaattattgc tatgaggcct
    16801 aaatgtataa tatttgatga agcaacagca atgttagatc catctggaag aaaagaagtt
    16861 atgaaaacaa taaaaagact taataaggaa gaaaatataa ctgttataca tataacgcac
    16921 tttatggaag aagcagtaga agctgataga gttgtagtta tggaaaaagg aaagaaaatc
    16981 ttagagggaa ctcctagaga agtattcagt aaaataaaga tgttaaagga aatcggttta
    17041 gatgtacctt gtatgacaga gttatctagt ttattaatag aagaaggtat aaatattagt
    17101 agtgatatat taactgtgga tgagatggtg atggaattat gtcaattata gtaaagaatt
    17161 taacacatat atataatgaa gggatgcctt ttgcaagtaa ggcacttgat gatatttctt
    17221 ttgagattaa agatagagat tttgttggtc ttataggtca tacaggctca ggaaaatcta
    17281 cattaataca acatttaaat ggattactaa agccttcctc aggagaaata tttataaatg
    17341 attttaatat aacagataaa aacttgaatt taactgagat tagaaaaaga gtaggggttg
    17401 tatttcaata tccagaatac caattgtttg aagaaacgat tgataaagat atagcttttg
    17461 gaccctctaa tttaggctta gaggagtctg agatacataa cagggtaaaa gcatcaatgg
    17521 aagctgtagg acttgattat gagggattta aagacaaatc tccttttgaa ttatctgggg
    17581 gacaaaagcg tagagtagca attgctggag ttatagccat gaacccagaa gttctcatat
    17641 tggatgaacc aactgctggt cttgaccctg gtggaagaga tgaaattttt aacttaataa
    17701 aagacttaca tgaaaaaaag aatatgacta taatactatc atcacatagt atggatgata
    17761 tggcaaagtt agcaaaaact ttaattgtta tgaatcatgg tagcgtagaa tttatgggaa
    17821 ctcctagaga agtgtttaaa tcaaatgcta gtaaattaaa agatatagga ttagatattc
    17881 cacaagtttt agagcttgca ttgaaattga gagaaaaagg ctttgacatc agtgaggata
    17941 tattgacttt agaagaagca aaacaggaaa tattaaaagt tgtgagagga cgaggattat
    18001 gttaaaagat ataactatag ggcaatacta cccaacaagt tctgctattc ataaattaga
    18061 tccaaggata aagcttgtag cgacaattgt atttatggta tctatatttg tagtaaataa
    18121 attttggcct tatatagtag ttttattatg tttattagct atgataaaat tggctaatat
    18181 accagtcaaa tatattgtta agggtgttaa acctcttaaa tggattattt tgtttacatt
    18241 tcttataaat atttttttct taccaggtga tgaaatatgg tcatttggat ttttagctat
    18301 tacaaaacag ggtctaagac aagcaatttt tatggcaata agattaatat ttttagtagt
    18361 tggtacatca ttgcttactt taacaacttc accaatagaa ttaactgatg gaatagagag
    18421 attgttgaat ccatttaaga aaattggttt gccagttcat gaacttgcaa tgatgatgac
    18481 aattgcttta cgttttattc ctacattgtt agatgagaca gacaaaataa tgaaggctca
    18541 gatgtctaga ggtgcagatt ttgaaagtaa gaatcttata aatagagcaa agaatttagt
    18601 accacttttg gtacctttat ttgtaagtgc atttagaaga gctgatgaat tggctatggc
    18661 catggaggcc agatgttaca gaggtggaca taataggact aagatgagag agtctgttat
    18721 atcaagaagg gattatatgg catgtgtatt tcaggttgtt tatctgggag caattatagc
    18781 tactagattt atagcaattt aattaataag ttatagatat aatgaggtaa agtatgagaa
    18841 atataaaaat taaaatccaa tacaatggta agaattattg tggatggcaa aagcaacctg
    18901 attctttagg gatacaaggt acaattgaaa gggctatata tgatataaca aaagaagaaa
    18961 ccagtcttat agggtctggt agaactgatt caggagttca tgctattggt cagattgcaa
    19021 attttaaaat taattcaggt ataagtatag aaagtatacc aatggcacta aatgccaagt
    19081 tgccaaaaga catatcagtt atagaagcat gtgaagtaaa tgatgatttt cactccagat
    19141 acagtgcaaa aggtaaaaca tataaatatt tagtatataa tagcaagttt agaaatccaa
    19201 tacttagtga gatatcatat caagtaaaat atgaacttga ttttgataaa atgtgttcag
    19261 aagcaaaaag tttattagga acacatgatt ttaaaggttt tatgagttct ggttcatctg
    19321 taaaagatac agttagaacg atatatgata ttgatataag taaaaaagat gacttgatta
    19381 cttttgagat tagtggtaat ggttttttat ataacatggt gaggattatt gttggaacac
    19441 ttgttgatat gggtcgtggc agaattaacg aaccattttt agatataata caatcaaaaa
    19501 ctaggtcaag atgtggacat acagctccag cacaaggatt atttctcaaa aaagttcatt
    19561 attaacttga cacaccaggc tacatgtatt aaaatatatg agaatgtgtt aataagtcca
    19621 cttgccccgg acttgacata aacggtaaaa aaattttatg aaaagtagtt aaggagggac
    19681 agttatgaaa agttatatag ctaagccagc tgatgtacaa agaaaatggt acttagttga
    19741 tgctgaagga aaaacattag gtcgtttagc aacagaaatt gcgacagtat tgagaggtaa
    19801 acataaacca acatttactc ctcacgttga tggtggagat tttgttgttg tagtaaatgc
    19861 agaaaaaata gttttaagtg gtaagaaatt agatcaaaaa tattacagat accatactgg
    19921 ttatgtaggt ggattaaaag aaatatctta cagagatatg atggataaga aaccagaaga
    19981 agttatatca catgctgtaa gcggtatgtt acctaaaaat aaattaagaa gcagaatgat
    20041 gactagatta agagtatttg caggtgctga gcacactcat gcagctcaaa atccagaagt
    20101 tttaaacttt aaataagatt aataggtgaa aggaggagtt tataatggct aacgttcaat
    20161 attatggaac tggaagaaga aaaagttctg ttgctagagt aagactagtt gcaggtgaag
    20221 gaaatatatt agtaaatgga agagcattag aaaattattt taattatgag acattaataa
    20281 gagatgttaa acaaccatta gttttaactg gtaatgaaaa taaatatgat gttatagtaa
    20341 aagttgaagg tggaggattc actggacaag ctggagctat aagacatgga atatctagag
    20401 ctttattaaa agctgattta gatttaagac ctgctttaaa gaaagaaggt ttcttaacta
    20461 gagatgcaag aatgaaggaa agaaagaaat acggattaaa agcagcaaga agagctccac
    20521 aattctcaaa aagataatta cttatttttt tggaaaagca aaatccttta tttactgtta
    20581 ttcagaaagt attggtattt taaaaatgtt gggttaagtt aattattgat atataataaa
    20641 ataataagat atcttattag gatgtttttc attaagaaga acatcctttt tattttgact
    20701 atttaataaa aaacatatgc taataacatt taaattttat ttttataata ttgtaattta
    20761 aaagtttata taaggttata tattttaaga tattatttaa caatataaat tctgaatata
    20821 cgttatcaaa gtttataata taaactaagt ataatttatt gtatagtatt gaatgttaga
    20881 taaacatagt gaattaaata ggggcagaaa tataatatca ttacataata atatattaat
    20941 accaataaat aaagatatat caatattaaa aaaatttaaa tgtttgtact aatatatgga
    21001 atattatagt gtttttataa gtatacatat acagggtgat gttgtgagaa agtacataaa
    21061 acatataatt tttagttttg caatgatatg tctagtagta gtatccatat ttgaaattaa
    21121 aaatatttct gaagatgtta tcaagtatat gccagtaaca aacaaaacta taattttaga
    21181 tgctggtcat ggaggcattg atccaggtgc attaaataag gataagagta catctgaaaa
    21241 ggatattaac ctagcaataa cacttaagct tagagagctt atagaatcaa gtggtggcct
    21301 tgtaatatta actcgagaag atgacagtag cctttataaa gaagaaaata ataaaactac
    21361 aagacaaaaa tataatgaga atttgaaaaa tagaaaagaa ataatatcta attctaatgc
    21421 caatatgttt gtctctatac atcttaatgc atttgaacaa tcaaaatact atggagctca
    21481 aactttttat cctaaagaca aacaagacag taaagaatta tcgaagtgta ttcaagaaga
    21541 acttaaaaga gtagtagata agacaaacaa cagagaagtc aaaccaaggg atgatatata
    21601 tcttttgaaa gaaaataata ttccatcagt actgatagaa tgtggttttt tatcaaatga
    21661 aaaagagtgt aaactcttaa ctgatgaaac atatcaagaa aaaatagcat gggcaatcta
    21721 cataggaata caaaaatatt taagttgaaa taagtataaa aataggtcta aatatgtaaa
    21781 tagcttgtat taaagcagtt aaaatgcatt aatataggct atttttattt tgacaaaaaa
    21841 atatttaaaa taaaagttaa aaagttgttg acttagaata atatagatga tattatatat
    21901 gagtgcccaa aaggagcacc aaaataagac
//
LOCUS       DAEQJM010000059        21887 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.059, whole genome shotgun sequence.
ACCESSION   DAEQJM010000059 DAEQJM010000000
VERSION     DAEQJM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21887
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.059"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            245..826
                     /locus_tag="KRQ43_002810"
     CDS             245..826
                     /locus_tag="KRQ43_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743155.1"
                     /translation="MLYLLKINQFERSYDIGIFKNEQSIYKFIEKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHYWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
     gene            complement(914..2725)
                     /locus_tag="KRQ43_002811"
     CDS             complement(914..2725)
                     /locus_tag="KRQ43_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH2743156.1"
                     /translation="MKKKYDFLIYSAIWLVIIIFFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILYNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(3549..4328)
                     /locus_tag="KRQ43_002812"
     CDS             complement(3549..4328)
                     /locus_tag="KRQ43_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBH2743157.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
     gene            complement(4341..5075)
                     /locus_tag="KRQ43_002813"
     CDS             complement(4341..5075)
                     /locus_tag="KRQ43_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBH2743158.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            complement(5104..5307)
                     /locus_tag="KRQ43_002814"
     CDS             complement(5104..5307)
                     /locus_tag="KRQ43_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743159.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            complement(5310..5867)
                     /gene="frr"
                     /locus_tag="KRQ43_002815"
     CDS             complement(5310..5867)
                     /gene="frr"
                     /locus_tag="KRQ43_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBH2743160.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            complement(5893..6597)
                     /locus_tag="KRQ43_002816"
     CDS             complement(5893..6597)
                     /locus_tag="KRQ43_002816"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBH2743161.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            complement(6682..7593)
                     /locus_tag="KRQ43_002817"
     CDS             complement(6682..7593)
                     /locus_tag="KRQ43_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBH2743162.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            complement(7672..8385)
                     /gene="rpsB"
                     /locus_tag="KRQ43_002818"
     CDS             complement(7672..8385)
                     /gene="rpsB"
                     /locus_tag="KRQ43_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBH2743163.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            complement(8592..9776)
                     /locus_tag="KRQ43_002819"
     CDS             complement(8592..9776)
                     /locus_tag="KRQ43_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH2743164.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADGKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNEKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGVIKYYTSSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            complement(9880..10938)
                     /locus_tag="KRQ43_002820"
     CDS             complement(9880..10938)
                     /locus_tag="KRQ43_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HBH2743165.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTI
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCIFLENCDFNRTIFSKNYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            complement(11152..11796)
                     /locus_tag="KRQ43_002821"
     CDS             complement(11152..11796)
                     /locus_tag="KRQ43_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2743166.1"
                     /translation="MEQHSKVGNFGDLLKVLLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQRPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            11981..12604
                     /gene="ytaF"
                     /locus_tag="KRQ43_002822"
     CDS             11981..12604
                     /gene="ytaF"
                     /locus_tag="KRQ43_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HBH2743167.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLELNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            complement(12667..14577)
                     /locus_tag="KRQ43_002823"
     CDS             complement(12667..14577)
                     /locus_tag="KRQ43_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH2743168.1"
                     /translation="MNSNTFERLQLNEVKDLIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILSYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(15114..16181)
                     /locus_tag="KRQ43_002824"
     CDS             complement(15114..16181)
                     /locus_tag="KRQ43_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBH2743169.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHTGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSEDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            complement(16427..17422)
                     /locus_tag="KRQ43_002825"
     CDS             complement(16427..17422)
                     /locus_tag="KRQ43_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HBH2743170.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRRNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            complement(17681..18940)
                     /locus_tag="KRQ43_002826"
     CDS             complement(17681..18940)
                     /locus_tag="KRQ43_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH2743171.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLTYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            complement(19179..19808)
                     /locus_tag="KRQ43_002827"
     CDS             complement(19179..19808)
                     /locus_tag="KRQ43_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBH2743172.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            complement(20001..20162)
                     /locus_tag="KRQ43_002828"
     CDS             complement(20001..20162)
                     /locus_tag="KRQ43_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743173.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            complement(20505..21665)
                     /locus_tag="KRQ43_002829"
     CDS             complement(20505..21665)
                     /locus_tag="KRQ43_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH2743174.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALVVTQILHMLA"
BASE COUNT         7142 a         3671 c         2171 g         8903 t
ORIGIN      
        1 tcaattatag tttattaaat ataaatatgt taaaataaaa caaaaccata agttcaaaaa
       61 ttaagcttta tatatattta tctcattatt ttactaaaac ataactatat aaaaaatatt
      121 tactattata tatctattta aaacacatca ttatagtatc atataaacat atgtaaatat
      181 ataattaaaa aagctaaaaa ttagtaaatt tataaaaatt atattttgaa taaaaggaga
      241 aagaatgttg tatttattaa aaattaatca atttgaaaga agctatgata taggaatttt
      301 taaaaatgaa caatcaatat ataaatttat tgaaaaaata ccctttgtaa aaaaagataa
      361 tagtaatttt aattatacaa attactatat ggaatttgaa gatattcctg aatattatga
      421 agtaaatttc aataattatt tatatattat taccaggttt tcattcattc cagatggaac
      481 tgagatattt tttacttggg aagaaatcca ttattgggat gaaaaagttg ctaccgagaa
      541 aacttttata aatggcgaaa cattagtgga ttcatataac tttccaaata atgaagtgaa
      601 agactacata caaaagcgag aatcattata tatagaaaca aaaaaatatt atgaagaaaa
      661 aggattaaaa attgagagac atgcactcgg ttcagaagat ggtgaatatg ttgaacttac
      721 aaatgattct atactttatt tactagatat agaagcagtt gaaataagag aacaatcaaa
      781 aaatatagaa gaatttctat ataagtacaa aaaacgtttt aaataattta tattttaaaa
      841 tacataacaa tacattgagt catttaacga aatataaaat gactcaatgt atagactgat
      901 aaaaataatt atattatttt ttagttacat atttgttaaa aaattctttt tcttctatcg
      961 gtttagagaa ataaaaccct tgtcctacat cacatttaac tgtatttaaa aattccaagt
     1021 cttttttagt ttcaatacct tcacatacaa cagacatgcc tatacgatgt gacatttcaa
     1081 taatacactg aataatacta tatactttct cccggttaaa tgtttcttta agtaagcttt
     1141 tatctaactt caatccatta atagatagag aacataaaag acttaatgaa gagtatcctg
     1201 atccaaaatc atccatcgaa attaaaaatc ctaacttttt aagctcctct aaaatcgaaa
     1261 taactggttg agatatttca ttaaaagcac tttcagttac ctctatctct atatacttaa
     1321 aaggaatttc atattcttta acagtatcta aaaacctttg ataaaagcta ttttggtaaa
     1381 tagtaaccct tgaaaaatta actgcaatcg gatatgtata ttgatttttt ttcataaacg
     1441 ttttttttac aaatgaacac gcttttttta acatataaaa gtccaattca ataataaatc
     1501 cacttttttc aaacaatgga ataaattcat ctggtgataa aaaaccaagt tctggagaaa
     1561 accatcttac aagagcttct gcgcttacaa catttaaaga agatatttga aatttaggtt
     1621 gcaaatacat atgaaattct tcattttcta tcgctttata catataatta taaatactat
     1681 tttccatttg taactgtttt aacagatttt cattatacca tactgtggag gaaattcctc
     1741 ttgttttact taccttgtgt gcaatatttg ccttatccat tatagaattg atggatttat
     1801 aacctaaatt atcaatttca actaagtacg ctcctataca ataagatata gtttgagtta
     1861 cattcatatc taattcagag attatagcat tagttagcat ttcccgaata tcctctaaaa
     1921 gagaatctct atattttgca agtattacaa aattatctga accaattctt gcacaagttt
     1981 ctttgatatt aaaagtttta gaaagtgcag ctgcaactat tattagaact ttatctccat
     2041 attcatatcc atgtgtatca ttaatatatt taaaattgtc aatatcaata tttagcagta
     2101 catactcttt gttagatgca ttgtacaaaa tttcaatcgc tctgttttca aatgcaacct
     2161 gattttttat ttttgttaaa ttatcagtat aaaatattct tttaaacctt tttttattat
     2221 aatattccca aattaaaaga cttattgttg agaatataag ataaataaat agtgcagtag
     2281 caaaagaata caattttgca ttagagtgtt tttcagatat aaaaacaatt tgattagaca
     2341 acacagaata ctcttcactc aatttatata atttatcacc tgaagcacca tttctaactt
     2401 ttataatttc tttcttcata gattcccaca tagaatccat ttgatttagt ttttgttgaa
     2461 attctttatt atcacatctt tgaaatccat tttctccatt acctgttctt agctttatca
     2521 gaatattatc cagtcgtttt atcaagtcat catttctttc attattcaat tcttgcttaa
     2581 caaccttttg agtttcactg cgaatagtac cagtgtgact tataatttta atatgctcta
     2641 tactatgata tagagaaaat ataaaaaaaa taataataac tagccaaata gcagaataaa
     2701 ttaaaaaatc atattttttc ttcattattg ttacctcatt tgtaatatat ataatttgca
     2761 aataatcaat ctcttataaa aaatgattat caatatttta cagtgatatg tatttatctt
     2821 aagtagttta atcatttata ccctataaat tatacaaatt catcacctcc aacacaaaca
     2881 gcaatatacg tttttctaaa atttcttttt aaacattcat caacactatc attaaatcat
     2941 ttttaaattg ctcaattaat ttactgcatc acttcttttc ttataaaata tcaccccaat
     3001 aatatatttg tataatgtct ttatgtctct ttttaaattt ggcatataca taatctatat
     3061 tttaataaat aattaaaata ctatttacct acaatttaac tctttgaatt tattttatca
     3121 tattatgtaa atatattcct tttttttggt atattactta aattatatct atttttgtgc
     3181 aataagacca ataatttact tatttcttat taattatatt taaaaataaa atttataaat
     3241 ggataataaa ttagttacat ttatacatat atattataaa tatataataa agctaaaaat
     3301 atcgaaatta ttaaacaaaa aaatattttt taatgatagt tatagtataa aaaatatact
     3361 cactacaaat atagtatact attataaagt aatacttatt cttataaaat tccccaaggt
     3421 cttctaaatt tttgaacaat gaaaatagcc atgtaactaa taactgcaga atatctctgc
     3481 atttaaaagt tacatagcta ttttcattac tagcaattat agattgctct tttaaatcca
     3541 accaatcttt atctaataaa aaatttaatc gcactatata caaaaggtgc aactaatata
     3601 acactatcaa atctatctaa tataccccca tgaccaggta ttatctttcc ataatccttt
     3661 atccctacat atctctttat agaagatgca aataaatctc ctaattgagc tattacactt
     3721 cctatacttc ctattatcgc taattgaagc aaatcaatgc caaataaata tccaaataaa
     3781 atacaacaaa gtgtacttcc tattattcct ccaatagctc cttctatagt ctttttagga
     3841 ctaactttag gaattagctt atgttttcca agtaaataac cactaaaata tgcaaatata
     3901 tctgtcataa aagatatcac aaatataagc catacatata tactaccttt ttcaaatcca
     3961 tttatagtta taattataaa atctaaaaat actcctatat aaaaaactcc taaaaacgta
     4021 atcgaaacat ctataacatt gtttttgccc atcaacatat aaattatact tgctaaaaat
     4081 aaaataaaaa ttactgcata agtatattct aatggtaaat taaaaatatt ttttacagct
     4141 aaataaatag aaaataaata tcctataatg aatattggat gtacatcttt tattttaaat
     4201 gccttataaa actcatgcaa tgcaatataa actattgctg tctcagctat atatagagga
     4261 atacctccat atacaacaaa tagaaataat ggaaccagag ctagtgaagc aataattctt
     4321 gtaagcataa aataatctcc ttacttaagt cctccaaatc ttctatccct tctttgatat
     4381 acgtatatag ccttctgtag ttcttctttt ttaaaatcag gccaatgtat atcagtaaag
     4441 taaaactcag aataagcaac ttcccaaagt aaaaagttac tcaatctttg ttcaccactt
     4501 gttcttatta ccaagtctgg atctggtata gactttgtgc ttaaatagtt ttttataata
     4561 tcttcatcaa tattgtttat atctatttta ccactttcac aattttttac tatatctata
     4621 agagcatttt ttatatctgc tctacttccg tagtttaatg ctaaatttaa gttaactcct
     4681 gtattgtttt ttgtcagttc cttagctgag tttaattctc ttatacaagt ttttggtaaa
     4741 gcacttatat ctcctatagc agttactttt acattgtttt ggtgaagttc agctatttca
     4801 tttcttaagt atgtagataa taagttcata agtgtgtcaa cttcaagttt cggtcttttc
     4861 cagttttctg ttgaaaatgc atataatgtt aagtgcttaa cacctaattt tgagcattct
     4921 tttactatat ctcttatagt ttctactcca gccttatgtc ctgcagttct tggaagaaat
     4981 ctagcttttg cccatcttcc atttccatcc attataatag caatatgagt aggtatgtta
     5041 tttaagtcta tatcatatat aatgttgtta ttcatatttt gcctccaata ttgttctgac
     5101 tccttaaact aaggagtcag aaaagtatgt gattatcagt tctacactat cacctatctc
     5161 agatattttt ataactctag gaactacaag tttttcttta tcctttttac cttcaataga
     5221 ttttacggta taatttatat tttgctcatc aaaatattgt tttacctcat ctacatgaag
     5281 acctaaaagg ttataatatt ttttcaatat tatacctcca ttatgtcctt ttctttttta
     5341 gataataatg tatctatttc ttttataaat ttatcagtca ttttttgaac ttcatcttgt
     5401 gcttttttta attcatcttc agttaattct ccgccttttt ccatcttttt aattttctca
     5461 ttggcgtctc ttctttcatt tcttattcta actttaaatt cttctgcagc tttactagct
     5521 tttttagcta attcttttct tctttcttct gttaaagcag gtacagaaag tcttataacc
     5581 tcaccatcgt ttgatggatt taatcctaag tctgagttag ctatcgcttt ttctatttca
     5641 tgcatagcag atttatccca aggagatatc attaatattc ttggttctgg tacagatata
     5701 gcacctattt gatttattgg agttggagtt ccataataat caactcttat tttgtctagc
     5761 atttgtgcat tagctcttcc tgctcttata gttccaaatt caaactttaa agcatcaatt
     5821 gtcccattca ttttctcttc taattgctta tgtatttcca gtttcataat tttactcctc
     5881 cttcattctt cattatttta cagtagttcc tatattttcg ccttttactg ctcttattat
     5941 attctctgtt gtaagctcaa atacctttat tggaatttta ttatccatac ataaagatgt
     6001 agctgtagaa tccattactt ttaattcttt ctgtataact tccatgtaac ttaattctgt
     6061 aaatttctta gcatctgcat gtacttttgg atccttgtca tatactgcat caacattttt
     6121 agctagcaat ataacttctg cttccatctc agcagcacgt aaagcagcag ttgtatctgt
     6181 tgtaaagtaa gggtttcctg ttcctgcacc aaatataaca actctttcct tttctaagtg
     6241 tctaactgct cttcttctta tatatggttc tgcaatttgt ctcatgtcta tagcagtttg
     6301 aactcttgta gcaacatcta tattttctag tgcatcctgt agcgccattg cattcataac
     6361 tgtagctaac attcctatat agtcagcagt agttctatcc attccttcac tggttctgcc
     6421 tctccagaag tttcctccac ctactactac agctacttca acacctattt cttgtatttt
     6481 ttttatagca atagcaatat cattaactac atcattattt ataccaaaac ctctttctcc
     6541 tgctaatgct tctccactta attttaacaa tacccttttg tacattggtt tatccatcag
     6601 aaacctccta tttcaatcct tcatatccaa ttttttctat tttttaaaaa agagaacacc
     6661 tgcgtgttct ctctttggtt attacttaag ttgcttagca acttcttctg caaagttttc
     6721 ttctctcttt tgtatacctt caccaacttc gaatctcaca actttaacaa cttttatatc
     6781 agaacctact gccttagcaa catcagcaac taattgttta acagttatat ctggattttt
     6841 aacgaaagtt tgctctaata aacaaacctc ttttaattct ttttctaatc ttcctttaac
     6901 cattttttca actatattag ctggttttcc ttcatttaaa gcttgttgag ttaatacttc
     6961 tgtttcatgt gctatgtatt cagcatctac ttcatctctt gaaacatact taggattcat
     7021 agcagcaact tgcatagcta catctttacc taattctaaa actttagcat ctctagcttc
     7081 tgtttccatt tcaacaagaa cacctatttt tccaccaccg tgaatgtatc cagcaacttg
     7141 tccattagtt acaactttag caaatcttct aaagtctaat ttctcaccta tttttgcaac
     7201 tctattattt aaaacttctt gtaaagttat tccctcttta tgagtttcac ctaataaaga
     7261 agctatatct tctttatcag tagctaatgc catacaagca gcatctttaa cgaacacttt
     7321 gaagtcttcg tttttagcaa cgaaatctgt ctctgagtta acttctacca tagaagcaac
     7381 tgtattatca tcattcattt ctattgcaac tagaccttca gcagcaactc taccagcttt
     7441 tttagcagct tttgataatc ctttttctct taataaatct actgcttttt ccatgtttcc
     7501 ttcagcttct tgtaaagctt tcttgcagtc catcattcct gcgcctgtac tttctcttaa
     7561 ctcttttacc atttgagcag ttatattagc cattttttaa gtttcctcct acttattcta
     7621 ttccatatta taaatggtaa gggcgaccct taccatttaa ttgtcaaatt attattcttg
     7681 gtcttcagct acttcttcct cagcaccttg tctaccttca attacagctg ttgccatagc
     7741 accagttatt aattttacgg ctcttatagc gtcatcattt cctggtatag caaagtctaa
     7801 ttgttctggg tcacagttag tatcaactat accaactact ggtataccta atctatgagc
     7861 ttcttgaata gctatgtttt cttttcttgg gtcaactacg aacattgcac ctggtaattc
     7921 aggcatgtct tttattccac ctaagtattt ttctagtttt tctttttcag ctcttaattt
     7981 tataacttct tttttaggaa gaacattaaa tacgccttct tcttccattt tttctaattc
     8041 tcttaattta tttattcttg tttttatagt tttgtggttt gttaacattc cacctaacca
     8101 tctttcatta acaaagtaca ttccacatct ttcagcttca tcttttatcg catcttgagc
     8161 ttgtttttta gttcctacga ataagattgg ctttcctgtt tcagctactt ctttagtgaa
     8221 cttgtaagct tcttcaactt ttttaactgt tttttgtaag tcgattatat atattccatt
     8281 tctctctgtg aatatatact tagccatttt agggttccat cttcttgttt ggtgaccaaa
     8341 gtgaacacct gcttctaata attgtttcat tgatattact gacatatctt acctcctggt
     8401 tttatacctc cagcttgatc ttctccctaa aaaaccatgt aataggcacc ttttaaggat
     8461 cccaatgctg tgtgtgattt attttatttt ttcacctcta gtagtatatc acagaggcga
     8521 agaaataaca atattttttc catattttct atttttatat ttttttgtgt attttatacc
     8581 attttttgaa tttaatttgc aaatttcatt tttaattttg tttttaatga tacgttatct
     8641 atactattat tacttactat atctacactt ccaagtaagt cacctgaact agtataatat
     8701 tttataacac ccatagtatc acctttttta acagggtact ctatattttt aatcttaact
     8761 tctgatttta tactttcatc atcttttaat attgtataaa gttcatcttt tgcttttaat
     8821 gtaacctcta actctttcat tccttttata tatttcttac caataaagct atctttatca
     8881 attacttttt tcatattgaa attttctttt ccatatttca gtagagctaa tgaagcagag
     8941 gttcttttat ttttatggtt agtacctaat acaaccccta ttactctacg ttttttctca
     9001 tttttctcat ttttatttac aaccatagaa aatgataagc aatatccagc attgccagta
     9061 tatccagttt ttataccatc tacttctggt ataattctta ataatgcatt tgtattgctt
     9121 ttttcaaaac ttctatctga atttgtatat gtctccatat cagttatagc tgttacttgt
     9181 ttttcataat ggtcaaacat gtattttcca agaatagcta tatcttttgc agtagagata
     9241 ttttcttttg ctggtttttt ggggttgctt aaatcgtata ttggaagacc atttggattt
     9301 agaaaatgtg tattactcat tcctatttct tttgcttttt tattcattct atctacaaat
     9361 gcttctttcg ttttacaaat atgttttgct atagcaattg ccgcatcatt tcctgataca
     9421 atcataagac ctctcataag ctctataagt ggcacttctt caccatcttt aagtttataa
     9481 cttgaccctt ttactgatgc aatagatttg tctattttta ccttatcagt ttcttttact
     9541 tctttatttt caatagcttc tattgcaagt aaaaaagtca tcatcttact taaactagct
     9601 aatggtacct tcatatcagg ttctttacta tataaaactc tacctgtttc ttggtctata
     9661 agtatagatg tttttgaata cttgtctaca gatttaccat ctgcatatga ataatttggt
     9721 attataaaaa ctagaatcat ggctaatgat ataatttttt ttagtgcatt tttcaaattt
     9781 ttcaccttct tggattatta agtatattta tatttaaatt ttccctattt ggtccaattt
     9841 atatctagta attaatacct atccatattt acacaaatat taccttatca ttcttttaat
     9901 aatcacagat gcccaaattg ctcctattgt aactccaaaa aatacttcta tacctgccaa
     9961 tgctttccca atcaaacttg tagcaaccat atctccatat cctactgtac taaatgtagc
    10021 catgctaaaa taccataaat ccatatacat tttgaaaatc tcacttagtg agtaatcacc
    10081 tatattgttt atatctaaag ctacaagtgt gctatttgaa ctttctatgc ctacaaataa
    10141 gtataataaa gcaaaaacac ttattattgc tataatcact aataatatat tccatggctt
    10201 ttctccataa cctgttgtgt aacgtgctat ttggtcaaaa aatttttcaa ctaaataatc
    10261 actgaaagta ggataattag aacgtttcat tattttacta ctataaattc tttccttata
    10321 atagtaaaat cctatcatct catattctcc aatttttgtt gcttgatttc tagctattct
    10381 ataatttatc ttgccatgct catactcact ttttccatat tcaacattct ttaacacaaa
    10441 ttttgtacac atgctaaaaa ttattccatc cattcgtgga aaattttcta ctttattaac
    10501 taccaaatca ggtcctttaa atttcacttt ttcaaatata cggtcattta tatagttttt
    10561 actaaatatg gttctattaa aatcacagtt ttctaagaat atacaaccat taaataaaac
    10621 tttatctcta aattctgtat agttaaaaat aatattcttt ttaaaaatat attttttaaa
    10681 atttgctttt tgtttaaata tggattcaga aaaatccagt attttataat tgtaagttaa
    10741 tatttcttcc gcattaaatt cattttcaaa aacaaatcca ttaaattcac ttatctcttc
    10801 tttatgaata gtatccatca tcaactgtat ctcttcatca gacttatttt ctttatgaaa
    10861 gatacaatat ccagaagaat ctgcttctct atgacatttt tttctctcat ctatcttaga
    10921 tatccattta caattcataa atatatatcc tccagtacaa aacaattatt actattttgt
    10981 attagtttgg atattatttt attttatata cttaaatagt tacaaaatat atattagatt
    11041 cttagtttta aatttttaat ctacttcatt gtgcttttaa tttgtttcat ataaaaaata
    11101 ataaatttta tatactttga tttatttata tattaaatat tattctaaaa cttacttatc
    11161 atttttaagt aattttgtaa ctatatttaa tgctactaaa tcatccataa atcctattgg
    11221 gaacacgaag tctggaatca catctgttga tataacaaag taaagtagca tacttccaat
    11281 caataaatat ttctttattg taagtccatc tgtacaaaaa tcagcataca tttgtcttaa
    11341 tctatctgta aattgacctt gtttttcaat agaatctatt tttttattaa aattatcaaa
    11401 aagtaatttt ttaccttcat ctgtttggac atataactta cacttactta actctttttc
    11461 aatatttcca ttaaagttct tatcattgat taaatttgca aatccaagaa tatcatcaaa
    11521 gttactaaaa tcactatctg cattaaatat ttgattattg ctgtttctaa attcatatcc
    11581 tgaagctttc aacagttctt ctaggttaat atttaaatgt attgccatct tttctaaatg
    11641 atttatattt ggcctttgtt tattattagc tatacgagat atagtagatt tatcaattcc
    11701 acttttttta cttagttctc ccattgataa ttctttttca tctaataaaa ctttcaacaa
    11761 atcaccgaaa ttcccaacct tactatgttg ttccattatt ttcacctgct ttattatgat
    11821 tggttttata ttatatgata tgattctttt gttatttagg tgttgtatga tgttgaaatt
    11881 ttatcaacaa tttattggat tatctgtaac aatttatcca tttttacaat actataacta
    11941 atataagtac aaaatttaag agaaaggatg ttaatctact gtgattgaat caattttatt
    12001 agttacttct ctttgtatag atgcctttgt gacaagcttt ggatatggag taaataaagt
    12061 taaagttccc ttatattcaa atataattat cagcgtagtt tgttcagcta ttttagcaat
    12121 atcgcttttt gcaggtacaa tagttagaga ttttttacct caaaatataa caatgttaat
    12181 atgtttcttt attttatttt tattaggaag tgctagacta attgaaagtt tttttaaatc
    12241 ttattttaag aaaaaatcta tacactcaaa gaattataat tttaatatgt tagaccttga
    12301 attaaatttt aatgtaagta tcgaacctga tgtcttagat acaagtaaat ctaaagtgct
    12361 taaatctgct gaagcattta cacttgcact tgctttaagt ttagatggat tagctatcgg
    12421 ttttggtagt ggccttgtag gtgtgaatta tatacaagtt attctatttt ctttaatatc
    12481 aaatataatt gcagtattac ttggttgttt actaggaaat atgtttgtta aaaacgtaaa
    12541 tttaaactta tcttggttaa gtggtttaat cttgttagtc attggattta tgaagatatg
    12601 ttaataagaa agcaatctaa agataaactt ttctctttag attgctttct tttgtgcttt
    12661 ttatatttat tttctattct ctctaatttc tttctgaatc tttttaagag ctttttttga
    12721 acctctttga atatcttttt ctaattttct ttctttaaaa ctagtaaata atacatctaa
    12781 atcataccct tctggataca attctgatgc ttttatgcta agttgtaatc tttttatatt
    12841 tactgaaata aaattatcat taaacaatac ttctacatta ttaaacttgt ccataggctt
    12901 atatacaatt ccaaaatcat cttcatctag taattttacc ttatccccta cattataatc
    12961 tgtatagctt aaaatgactt cagaactatt tttatcttca atattagatt gtagcttact
    13021 tcttttaact aaatctaaat tgtagtttct atcaattaca tattctttag ctctatctaa
    13081 aactctattt tttattccca tttttttaga aataaaaaga gcattactat cttcagattt
    13141 tccaatagtt aacttataca atggttctaa cgtttcttta tcaaacatca taccagcatt
    13201 ttcaaattct ggatgtaatg tagcaaactt ttttatctct ccataatgag ttgatgctat
    13261 agttatacat cccattttgt aaaactcttc taataatgat attgctaaac cagctccttc
    13321 attaggttca gttccacttc ctatttcatc aaacagaaca agagtagaat tatttgataa
    13381 actcataatc tctgcaatat tttttatatg tgatgaaaaa gtacttaagg cattttcaat
    13441 actttgatta tcccctatat ctacaaaaac tttttcaaat acactaaatt cactaccttc
    13501 ttttgcagaa atatcaaatc cacattgaac cattaaagtt agtaaaccaa cagtcttaag
    13561 ggttacagtt tttcctcctg cattaggacc tgttattata agacttctat aatttttgcc
    13621 tatttcaaaa tctaaaggta ctgcatctcc tgttagaagt ggatgtttac ctttaattat
    13681 ttttatatag ccattattat ttatttttgg agtaattcct tttatttttt gactatactt
    13741 agcttttgca aataccatat cgtattctga aagtatctct atatttaatt ttatctgact
    13801 tatcttctca aatataagtt ctgttaaata agataatatt ttgtattctt caatagtttc
    13861 atcagctttt agcatagtta actctgtact taaatttgaa acactaatag gttcaataaa
    13921 tacagtattt ccttttgatg atgtatctaa tatagtacca ttaacttcat ttttataaga
    13981 agatttaatt ggtattacat atctatcatt tcttttactt attataaact cttgtatata
    14041 ctttttattt acagttgatg ttataaattt atttaatcta tcttttatct ttccttctgt
    14101 aatttctata tttcgtctta tcttttttaa ttctttacta gcattagaat caactttatt
    14161 agattttata cagtaattta tctcatcttc tatactttta cattctgtta tatttaaagc
    14221 ataagaactt aatgtaggtg aataaaattc tttttctaac ataaaagctt tcatcttcct
    14281 acaacctctt aaaaaatctt caatatttac aagttcaaca ggttctatta tcattccttt
    14341 ttcaatttta tctattgtag aacctgcatt aaacaatcct tcaagtggta tgtgattact
    14401 attttcaatt atctttctag cttctttatt ttctgctaat ttccttctta ctactccaat
    14461 attcccacta ggagttaatt tatctattaa attttttcct agcgaactta cacaatgtat
    14521 ttttattaag tctttaactt catttagttg caatctttca aatgtattac tattcattat
    14581 tttttctcct ttatttataa gtcatcgtct tttaaatcac cctatcattt actttgataa
    14641 tagttatttt gcgaacaact taataaataa ggagttatta tatatcaaac tccttattta
    14701 ttaagaagtt taactccgga ctcattaatg ttagtatttt ttttcataaa acacttctcc
    14761 ttttctattc ttatttaaac acttatacca gtgcttctaa tattattcca taaattatat
    14821 atttatgtca ataaaaataa tgttattaat gtttttgtac agtgaaaatt tttatagtga
    14881 aaataagctt atactttcat ttatattttg gaattactta tattgtcatc aattcatgta
    14941 tgtgtagttt ccaatacaat ctaactttgt aatcattata tatcaaagaa tttagctcta
    15001 taaattatcg tctctataaa ataaaaaaat agctaataat aataaaacac ttttaaatgt
    15061 tccataaaat tagctattta taatataatt ttaatctttt ttaactttaa aaattatcct
    15121 ttataagtaa tcaatggctt catagttgcc actacttgaa taagttcata ttctatcaaa
    15181 ctttcaataa tctgctctat attcttatat gcctctggag cttcttgaaa taataaattt
    15241 acatcattac atataatctg acttttaaat ttagtttgtt ttatagtatc tttactatac
    15301 ttacttttaa ggcgcgattt acaaactgaa cgagaccatt ttctacctgc tccatgtgat
    15361 agagaatata aagatatctc tgtattttca gtaggcataa ctatatatga tagactgcct
    15421 cttgaacctg gtataatcac agctcctctt tcacttgaaa cagcaccttt tctatgtata
    15481 aatttatctt cccttttctc tataaagtta tgatttatag agaatattgt ttcaacatct
    15541 tcagatgtac ctattgactg cataattttt ttactgatag cttcacgatt acgctctgcc
    15601 cacattaaag cattatcatg ttttttaata taatctattg ctttctcact ttcaacttca
    15661 agtccatctt tatcataaaa tttttttaaa atatcttctc cataatttct tgacccacag
    15721 tgaactaaca tcataatatc atcagatgaa aattttaatt gttcaaattg ttctttatta
    15781 taaatttcac ttatacattg aatttctaca aaatgatttc cactccctat agttcctaaa
    15841 tttaaaattg gacattcttc tttatatgtg ttttttattt ctatatcgga caaatcttta
    15901 atcttactaa gtgacttaat ccatttgtct tttttaaatt tcttttttag aaccccagtt
    15961 ttaaataaag tcattccgca tcctatatca tttccaatta tatgtggata aataatattt
    16021 ttagtctcaa ctgctaaacc tacaggtatt ttacctgtat gtaagtcagg taatcctact
    16081 actcttaaaa ttccatttaa ctttgaaata tcttctagtt gtttccttgc tatatcttca
    16141 atccaacatt tattacttgc tattattttt atattgctca taatttgctc ctttttaata
    16201 ttctcctgcc tttaaaaagt agcaaaaagc tgtgaccttt agccacagct tttttattct
    16261 aaactgtaaa agcaggtggc tatttgttaa aatactccta gacgtttaat acctcattat
    16321 tttttgttaa cataataacc acttcctttc ataatttaag actacactaa aatttctatg
    16381 tatatcattt atagacattg attttaaaat acttaatata caatttttat attatggaac
    16441 taataataat cattgaaatc atgactatag ctagaccggc aacaacaagt tttttatgta
    16501 atttttttct cattttactt ttatattctt ttttaacttg tataactttg tcttgtttct
    16561 gttcttcttc tttctcatct tcaacttcta tatatgcttt ttcatacatt actttactta
    16621 aatcaataat aatatcattg gctctagtat acttattatt tcttccaaga agccttttta
    16681 taacatttat aagttctgta tttccattaa ttgcttttat actattccaa tctaatccct
    16741 tatcaataga ttgtagcatt ttttcttctg aatttgattc tccaaaaggc aattttttaa
    16801 atatagattc aaatagaata agacctgttg caaaaaaatc actttcttta tcagtataat
    16861 ttatacatag ttgatgtggg cataaatatc tcctgtttcc atagcttctt gtattaaccc
    16921 cattatttgc ttttgtaatt ccaaaatcac aaatttttat attgtattct gtatctacta
    16981 ttatactact cgattttaaa ctaccatgat atgaatgatt cctatgtatc atttctaaag
    17041 cttttaaaac ttgtatcatt atgtttacaa ttgcttctaa atgaagataa ttacctagaa
    17101 ttaattcatc tagtccgata ccattaaagt cttcacttac aacataatat aatgttgttt
    17161 cttctgtaca gtgaatccca acatctatta tttttagtat ataaggagag tttatctcat
    17221 ctaaagcagt actttcatca attaaatttg aaacaaaatc ttcacaaata taattattgt
    17281 gctttataac ttttattaac acatttctcc tgtaaaaaac atctctagct ttatagattt
    17341 tgttaatttc taaaacgtca tcagaattta ctacctcata tctattgcct ataaaattca
    17401 accatgtcac ctcctcatac attttatata actaaatcta tttacaatta taccaatata
    17461 taggaatatt ttctatatat taatgattgt aatattaaaa caagaactaa tagtgttaat
    17521 ttttacaaaa aaggctgtct caaaatagag atacgcttct tttgtattgt tgaaatgatg
    17581 aaaatatatt tgatttcaca taaaaagagt gtctcataaa ctaaaaagtt cattttgaga
    17641 cactcccttt tatattacaa atatttctct aaaaaattat ctattttttt aattctttat
    17701 aagaactatt tgatatatgt tcttttttta tgacctttcc acttgaatct ttaaatattc
    17761 gatatgtaga atatttattc tgaccagttt gttttacctc tatagatata tttggtttgt
    17821 caccagaatt accatagatt actgatgata cacttcctcc acctgcataa tttttaatat
    17881 atacaggatg cttatatgga tttttaaact ttaagtttaa tcctccatcg ctcacagtag
    17941 catctcttcc tttaggcaca taagtagatg cagatgaatg atttgtaact tgagttatct
    18001 ccatacccga aagaagagcc gcattataaa ctgttgaaga tgtttgacaa acacctcctc
    18061 ctgctgattg ttctagctta ccataaacta taacaggtgc atctttgtaa ccatttgctt
    18121 tattactagg tcctgtaagt ttattgtatg aaaattcttc acctggcatt aataatacat
    18181 cactagtttt tcttgctgat aatcctacat tatatgacct accctctaca gcttgtgaat
    18241 aagtagttga atattgacct ataacagaat ttacagtttt tacttgttca gttgttatat
    18301 ctggtttttg aagatttact ttaagttcta aagttttatg ctctttattt tttatcatat
    18361 tatatataga ctctttattt gctgccaaat caaattctct acctacaaca gagtctgtat
    18421 aacttagtcc accacttcca acactaatag aagcattttt catcttaaca tttatactat
    18481 ctgctattga agacactttg gaactaagtt ttgcctcatc atattcagct tttatcttca
    18541 tatttgcctt attcactctt atatcaatat atttttttaa gttttgaaaa taggaccctt
    18601 tttttgtact ttcataagca tcttttacaa catcttctgt atcatatttt aaatcaatat
    18661 cttttggtga tattgtatat tttttcccat cataagtaag atttaagtct tctggagtat
    18721 acttatctgt tatagctttt aatgcctctg ctttagtcat atcagataca tttactcctt
    18781 ctatatatac atttttagcg attttcccat tgtacagaaa tttactgtta aaaaaataag
    18841 taaatccacc cattattaga actaaagctg ccaatacaat taaaacactt cgtttttttt
    18901 ctttacctaa tcttgaaact cttgttgttc ttctgcccat aacttcacct cattttgaca
    18961 ctagcttaaa tttgcataat agagttccca tttcaaaact accttagatt atatttgaat
    19021 agcttttgtt aaacaaggaa tttaatcaaa tgtaacttta ttgtaaattt atgtcttata
    19081 attagtttta tttttgatat tttttattat atttctttta ctatttctta acaaaaaatt
    19141 gtttatttta taacaactaa tttcatttat attgaaattt aaatgtaacc tattacagga
    19201 taatggtctg acaggtaaat tttttctact gtgtatcctt ttaattcagt atttttatta
    19261 acaaaaatgt aatctattct agagtttgat ttttcaaatg ttggtaagta agacttgttt
    19321 agtgaaatag ccatatcatt aaacatactt aaaaagacat ttttctcatt aaaatcacca
    19381 cataaaataa ctatccccac taatctgttc ctatagtcta ttatttcgtc taattgtttt
    19441 gctctctcct gcctatcaag tcccaagtga gtatttatta catttataat tcttccatat
    19501 gcatctatag ttatacaaag agctccccgt tgttcttttt tgctagttaa gaaaaaatga
    19561 ttactgttta acattttaga tgttgtaaat gtacaaatac catatatcat atttactttt
    19621 tttacatttg tagcaaagac accatccata tttaaaacag cttttaaagc taaaaattga
    19681 ggatataata cttcttgcaa acaaattaca tcacaatcca attgttttaa atataacccc
    19741 attttagtta gagttaatct attatttgaa tccatacctt tatgaatatt gtaggttact
    19801 attttcataa taatatcacc tcttatgcaa tataatactt actaaaattt aaacttattt
    19861 acttttcact taagaccatt atttatctta taaaattgag tacttataaa ctttatcaca
    19921 aaaaaaccta acttaagtat ttatattcta cataagttag gttttataaa ctattataat
    19981 atttattatt tcattcattt ctaatgatga ttctcctttt ttatcttttt caatttgcct
    20041 tcactaacaa caaataaaaa tcccatcttc ttgtatattt catccaattc aattaaagtt
    20101 acttcaccat tttttaaatt tgttaatgtt atatcttgta ttcttcttga tggaattatc
    20161 ataagttatc aacactcctt taaattcttt ttaatcttta tatttaaata tatttatgca
    20221 ttctgatata tattcataaa ttattaaaat aaattcaaaa aacacccgtt ctgcaaacat
    20281 tcgttctgta tatttattat acatcataca gacgttcgat tcaatataaa aattaaatat
    20341 atctcgtttt tagtaaattt tacaatatta tacactaaat atgtcaaaac atcttcttga
    20401 aatagattat cttgtcaaac aaaaaaaacc atttcagtaa aagcttctgc ttaaattgaa
    20461 atgacttttc ttatttaaat tattaatttt ataccatatt tttattaagc taacatatgt
    20521 aatatttgag ttaccacaag agcacaataa gtccctataa tatttcctag aagccccata
    20581 agtacaccta ctggtattaa tacaggattg tgaaccccag caatcattgg agctgtagtt
    20641 actcctccta tattagctat acttcctact tcacaagtaa ataaatcaag tttaaatagt
    20701 ttagcaagcc ctataaatga aatagcatgt acaaggacta ctaccaatcc aaacattatg
    20761 taaacaggtg cttctgacaa tccaaagaaa tttgctttac tacctgtagc tgcaaggagt
    20821 aaatacataa acacatttcc taccagtgta ctccctttaa gctttgatat ttttgtcata
    20881 cccaataata ttgatactgt agatgcaaca agtactaccc acatagtttc attaagtata
    20941 cctgaagttg gaagtatctt ggatacaatt tgtgcaaaag acgcaactcc aaacccaaca
    21001 gaaagtaaaa tcataagttc tacaaacgta ggtgccgtat tatctttatt ttctttttca
    21061 agttttgatg taacctcatc tataaaactt gtatcgcact ttgtccattt gttaaattta
    21121 ggtccaaatt tcacagacat tagacaaaca gacatccata ctgtatatcc tatagaaccc
    21181 ataagtattg cataactaag tccttcttct gcaactccta gagcattagc tgctgcaatc
    21241 atatttgatg agccacctat ccatgaacca gatgctgccc caagaatttt ccatgaatct
    21301 gcacccattg aatttttaaa aattatgaat gctataacaa atccaagcat aaatgtaaat
    21361 gtagcacaga aaaatgataa taacatttta ggccccatct ttaatatttt tcttaaatca
    21421 cattgaatta acaagaacac taacattaat ggaaggaagt tcactgttat tatgttttga
    21481 tacgttccaa catcttcatt ctgtgcaaat aaaccaaatg atccaagtat agctgaacct
    21541 aagtatatta aaagcattgg attaataaca tcaaatacct tccatttcaa tttatcaacc
    21601 ataaaaaaaa ttacacctac gaatacaacc aagaaactac aatatacaaa tccagtctca
    21661 atcacattat acacaccctt tcttttccta attaatttga tttttatgat ttctaagtaa
    21721 agactttttc agataataga caattaaaat aaatactttt atctatatca tgctaattaa
    21781 atacatatat acctaactat tgacatatat taataaagat ttgcacatta attactttag
    21841 aaatgaataa tctgaattta aaatcttttt caacaattat tttatta
//
LOCUS       DAEQJM010000060        21733 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.060, whole genome shotgun sequence.
ACCESSION   DAEQJM010000060 DAEQJM010000000
VERSION     DAEQJM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21733
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.060"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            153..1658
                     /locus_tag="KRQ43_002830"
     CDS             153..1658
                     /locus_tag="KRQ43_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH2743175.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            1772..2470
                     /locus_tag="KRQ43_002831"
     CDS             1772..2470
                     /locus_tag="KRQ43_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH2743176.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            2755..3843
                     /locus_tag="KRQ43_002832"
     CDS             2755..3843
                     /locus_tag="KRQ43_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743177.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            4082..5272
                     /locus_tag="KRQ43_002833"
     CDS             4082..5272
                     /locus_tag="KRQ43_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2743178.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIEYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYTIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            5363..6865
                     /locus_tag="KRQ43_002834"
     CDS             5363..6865
                     /locus_tag="KRQ43_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH2743179.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            6937..8193
                     /locus_tag="KRQ43_002835"
     CDS             6937..8193
                     /locus_tag="KRQ43_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH2743180.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            8365..11139
                     /locus_tag="KRQ43_002836"
     CDS             8365..11139
                     /locus_tag="KRQ43_002836"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH2743181.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAQALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSILSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRSMNSNSKN"
     gene            complement(11204..11389)
                     /locus_tag="KRQ43_002837"
     CDS             complement(11204..11389)
                     /locus_tag="KRQ43_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH2743182.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKEVYKILQKLDIDFERVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            11761..12939
                     /locus_tag="KRQ43_002838"
     CDS             11761..12939
                     /locus_tag="KRQ43_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH2743183.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMFTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIVSIMIKIWLSRFNKFVGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKDMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      13065..13150
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            13263..16217
                     /locus_tag="KRQ43_002839"
     CDS             13263..16217
                     /locus_tag="KRQ43_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH2743184.1"
                     /translation="MKKGNKKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEDNSTDNKKPEQTSEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQTPEGEKSIDNKKPEQIPEEDKSTDNKKSEQALEDEKPL
                     DNKNTEKTPEEDNLLEDENLLKVLEEELNEDYGFVVKINNNTIETESMKKISFNLTYT
                     PTSKGIQAGDSITFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGK
                     IGLEAYVKKVDEDTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEG
                     RKSTTVFMPVKNKDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEV
                     SDFNIEQSKNSISVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQED
                     DATVSIFDRGDNYLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGM
                     RLTTSGEDGHDFRVVEVPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTI
                     NLSKEEVESKFFIAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKK
                     EVDKKVLNSSDNQIVKYKINMSTYGVYDAGQVNLLDEVNPSLKISNIKYSDNLELKKE
                     AGDGKNTIRLVNKYEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNVAQINGSSPPGV
                     ETTKQGYAFEAKKVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGVIQSSVKKPGI
                     YYLVEVMAPSGYEKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPVPPNTDEP
                     IVNPPVPPSTDKPRKPSNPSDTEDTIVINPPVPPSEDIINPPIPEILNPPVPPSEEVI
                     ETPVKQIVPIPEVVKPSVSEEKNNKAKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIV
                     GLVVLRRNKNTN"
     regulatory      16403..16488
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16588..17250
                     /gene="zmp1"
                     /locus_tag="KRQ43_002840"
     CDS             16588..17250
                     /gene="zmp1"
                     /locus_tag="KRQ43_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HBH2743185.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHAYSTTIQQNKDTLSQIVVF
                     PTGNYNKNEANAMVNRLANIDGKYLNVLKQDNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAEAFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(17368..18330)
                     /locus_tag="KRQ43_002841"
     CDS             complement(17368..18330)
                     /locus_tag="KRQ43_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH2743186.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHIFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVLSPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(18500..19690)
                     /locus_tag="KRQ43_002842"
     CDS             complement(18500..19690)
                     /locus_tag="KRQ43_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH2743187.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            19996..20442
                     /locus_tag="KRQ43_002843"
     CDS             19996..20442
                     /locus_tag="KRQ43_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH2743188.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEG"
     gene            20444..21538
                     /locus_tag="KRQ43_002844"
     CDS             20444..21538
                     /locus_tag="KRQ43_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HBH2743189.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVIKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMKMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            21626..>21733
                     /locus_tag="KRQ43_002845"
     CDS             21626..>21733
                     /locus_tag="KRQ43_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH2743190.1"
                     /translation="MKSLVLYSSLTGNTKKIAYAIYDEIQEEKDIKDVNE"
BASE COUNT         8560 a         2500 c         3714 g         6959 t
ORIGIN      
        1 tagaagtaat aaaaaaaaat aattaatata aaaatgtgta caaactaatg aatattgata
       61 tagtaagcta tcatatgaaa gagtatgtac acattttttt tactaatttt tcacaatatg
      121 aacataaata atttacagga aaggaatctt ttatgaaaat tcaaaatact gagtggggat
      181 atattgaatg gaaacatact tatgatgaaa ataatccaaa acaagctatg aatatataca
      241 ttgcagtaac tatgcctggt aagaaacatt ttaatcatgt tcattatggt caagagcaga
      301 tgatatatat tttagaggga gagggtttgt atattataaa tggagtttgg aagccatttt
      361 atcaaggtat gattttttat atagaatctg gtagcacaca tgaaactata aatacaggcg
      421 atagagaaat aaaagaactt attgtttcaa ataatgtaga tgatgtagga gagagtgaag
      481 ttatagatat taatcctaat aattatttaa agaagacctt gataaattat agtgaaagta
      541 cattaaattt gtatgcagca gtagaatcaa ttcgtggtca atttatagac ccgtttaaaa
      601 ttccattaat tatatatgat gattcatgga atatagtttt aaaaaaccct tattttccac
      661 ttttttgttt tgaaaaatgt aatcctatga aatttcctca aaattgtgat tgtatgaatc
      721 aaaaaagtag caatcaattt gtatgtgaat atgggataac tatatataat ataccaatac
      781 tgtacaaaag caatagcata ggtgttataa gaggagggta tgtactatta tctgatttaa
      841 atttagatac agagcataat aatttatatg atattccaga gggagctgct agaagtataa
      901 aacgcctctt gaaacaaata tctaaaaata taataaattt ttgctctttt aatgatataa
      961 gaaaggattt acaagaaaaa gagaagacta tagcaagaac atatcattat ggagagcaac
     1021 ttgaaatgaa tttaaaagta gctcaagata tggttactaa tttaagaata aatcatcact
     1081 ttttatttaa tacattaaat tcaatggcaa gcatagcact agatgatggt agttatgatt
     1141 tgtatagtgc aataatagat ttatcaagaa tgtttagata tacaatgagg tctgatttaa
     1201 gatttgtaga attagaatct gaaatattat acattaaaaa ttatttgaat ttacagaaat
     1261 tacgttatgg agatgcactt aaagtaaaat atcttattcc agagaagtta tataaccttt
     1321 ctgtgccttt taactttatt caacctatcg tagagaatgc atttacacat ggatttagag
     1381 atattgacac agaaaagcga attgaaataa ttgcaagatt agattctcag tatgctatta
     1441 tagagattca taataatgga actatcttag atggaaataa tatagacaaa ataaaggcag
     1501 gtattcgtag taataatggt catggtttgt ctttaatata tacaaaattc acatctgctt
     1561 atggaaataa ttttgatatg gatataaagt cgagtgataa tgaaggaact tacataatga
     1621 ttaaaattcc tattgaaaat tataaggagt atgtatagaa cttgtgaaaa attaataagt
     1681 tttataaatg ttaagaaata tattagatgt ttttatgttg ttttatatat cttacttttt
     1741 tatattatta agctaaaagg gaggtattct catgagaaga gcactaataa tagatgatga
     1801 agaagctgtt ctaaaaataa taacacattt tatagaaatg aaagatatgc caataaaaat
     1861 tgttggtaaa gcaacatctg gtgatgaagc agtagataaa atcattggtt tagagccaga
     1921 catagttttt atagatattc aaatgccaat atacaatggg ttagaagtaa tagaaaaaac
     1981 atctcattta tctaaaaaaa taaactttgt agtaataact gcatttaact attttgaata
     2041 tgctcaaaaa gctttgagat taaatgtaaa agatatactc cttaaaccat tggatatgaa
     2101 agaatttact aagtctgtag aaaaaattat tggatatcaa tataccaata atgatttatt
     2161 aaatgagata ctggaatata taaatctaaa ctatagcaat gacttaaagt taaatgattg
     2221 tgctagatta tttttaacca atccatctaa tatatctagg atttttaaaa gtaatttaaa
     2281 tacaactttt atatcatatc taaatcatat aagaatagaa aaatctattg aattacttga
     2341 aaatactaca aaaagtataa atgagattgc agaaatagtt ggatataata gcctaaataa
     2401 cttttataaa aactttaaga tagaaaaagg aatgactcca aaagtttata aactgaacac
     2461 taaaaattga aattgataaa taaaaagtca atatagataa ttgtttgagt gtgtctgaat
     2521 aagtatactt taattatgat aaaaattaaa gcgctttaaa catatttaat aatattaaac
     2581 cttataaaag ctgtacctat ttatataaaa aaatatatat aaataaaaag aaaaagatat
     2641 acaaaataaa aaaagtgaat taaatactgt ttcaaaaaga cagaattttc atttaattca
     2701 ctgagagttt atatttctta aaggaaggta actttataat ggaggtaatt taatatgtca
     2761 gacaaagtga atatgaaaaa tattatctgt attgcaggcg cttatctagc aacagcaatt
     2821 ggttctgggt ttgctactgg tcaagaaatt ctacaatttt ttgcctcaca agggtatatg
     2881 ggtttaattg gagcattaat atcaatggta ttgttttcat ttcttggtgc tgaagttata
     2941 actagaggta gagaattaaa acttaaagaa ccaacaagaa tttacacttt ttattgtggg
     3001 aagattttag gaaaatttta cgaatggttt agtccaatat ttttatttgg gattcttata
     3061 gtaatgattt caggtgcagg ctcaacttta actgaatact atggtataaa tccttactta
     3121 ggaagagtat tgatggctgt tgctacttta attacagtgt ctatgggttt agaaaaatta
     3181 gtaagcatac ttggacgtat tggaccagtg atagcagtat ttacaattgc tgttggatta
     3241 ataagcttgt ttaagcattt tgatggttta tctatggttg gagaagctat gaaaaatatt
     3301 gaagttacaa aagcatcaga aagtccaatc gtttctggtg taatatataa tacattaaat
     3361 attattgtaa tgattgtttt tttaacagga atgggagctt ctattgaaag taaaaaggat
     3421 gctttttggg gaggtttatt aggtggaata gtgtttatga ctgctggtat agttatgtat
     3481 ttggctatga tttcagatat aggaaatttg tatatgaaag aaataccatc actttattta
     3541 gcagataata tatctcctat tgtaggtgta tgtttttcag ttgcattaat attaggtatc
     3601 tatacaacag ctgttccact tttatggtct gtaaccaata gaattgttga agatgaacat
     3661 cctaaattta aattggtaac aacagtaata gctattttgg cttgtatagg tggtttttta
     3721 ccgtttggta aattagtaaa cattttatat ccatatacag gttatatggg gcttttaatt
     3781 ttagtctgta tggtgtataa agcaattaca tgtagaaaaa aatcaacaca aagtcaggaa
     3841 tagagtcacc tattaatagt ttttatttaa agaaattttt tatataatcc gaatttaaaa
     3901 agtcaaaata gttaaataaa ttgcaaaaca tgataatata tttaattaaa ataatatagt
     3961 aaaatataaa tataaactaa aattaaattt ataaaaaata tctttataaa gattattaac
     4021 ttatataatt tgtagttaaa ttataaaaaa taaaaaaata aaattttgga gaggtgttag
     4081 tatgcatgaa cttattttaa tctcagaaaa gtataaagaa gatattttag atttttttac
     4141 agatattcat atgcaccccg aattaagttt taaagaattt aggactacaa aagctataaa
     4201 agatttatta gtaagtttag acatagaaat attagattta ggaatggaaa caggagttgt
     4261 tggattatta aaagggaagt atgatggtcc cacagtagca ctgagaggag atattgatgc
     4321 attgccaata tatgaagagg ttgatattga gtataaatcc agatatgatg gtataatgca
     4381 tgcatgtggg catgatatac acacatcttg ccttgtagga tgtgcatatg tattgtctca
     4441 tattagagat agtcttcatg gaaatgtaaa gtttatattt caaccagccg aagaagtcaa
     4501 taaaggtgcg aagatgctag tggaacgagg agtaatggaa aatccaaaag ttgatgctat
     4561 atttggactt cataatcatc cagatatacc ttgtggaaaa ataggtgtta agttaggtgg
     4621 gttaatggca gcagtagaca ctattaagat agaagtaaat ggatttggag gtcacggagg
     4681 tataccaaac agaacaatag accctatagt agcatcaagt gcaattataa tgggtattca
     4741 aaccatagta agcagaaaca taagtccatt agaatcagct gttatatcaa taggtactat
     4801 aaatggaggg actgcaaata atgtaatttc agaaaaggta gatatgacag gtacatgtag
     4861 aagctttagt aatgaagtac gaaagaaaat atcagaaaat ttagaaaata tagtttgtga
     4921 gatagctcgt ggatatcaag caactgcaaa gctagattat ttatttgatt taccagctgt
     4981 tataaatagt aaagagatgt acacaatagc ttgtaagtct gtgtgtgatt tgtattcaga
     5041 agatgctata gttgatccaa taccttctac aggaggagaa gatttttcta tatttatgga
     5101 aaaggcccca ggattttttt actggttagg ggtaggcaat aaagaacaag attgtatata
     5161 tcagtggcat aatcctaaat ttaaagctga taaaaattct atattggtag gtacaaatgt
     5221 actatgtcag tctgttataa attatatgga taaattaaaa aataaaattt aagatagagc
     5281 attctggaga taaagtttat gagggggtat tagtttgagg aaaattaatt cacaggaaaa
     5341 aaacaaagat agtggattat tgatgagggc actaaatgtt gtagagagag caggaaataa
     5401 acttccagac ccagtaacca tatttttatt actatgtata attgttgtaa tattgtcagc
     5461 agttatatct aatttaggag tagaagaaat acatccttct acaaaagaag ttgtaaaggt
     5521 agtaaatcta ctagagaaag agcagattca atcatattta ggtagcatag ttacaaactt
     5581 ccagtcattt gctcctttag gattagtact ggttacaatg cttggagcag gtgttgctga
     5641 gaaatctgga tttatggaag tgttaatgaa aaagggtata agtaaagttc cacaaaaact
     5701 tgtaactgta gcaatcgtat ttgcaggtat gttatcacat acagcagcag atgtaggatt
     5761 tataatatta ccaccacttg cagcacttgt gtttttagga attggaagac atcctcttgt
     5821 aggtatgttt gcagcttttg caggtgttgc agggggattt gcagcaaatg ttatgcttag
     5881 tactacagat gtattgttag ctggatttac aataccagca gctcaaatga tggacccatc
     5941 ttaccaaggc aatccagcaa tgaatcttta ttttgctttt atatcagcga tagttttaac
     6001 ttttgcagga gcatttgtaa ctgaaaaatt tatagctcct cgttttacaa aatataatga
     6061 ttcaacaaat gataaggata tacaggaatt gagtgaactt gaaaataagg gtataaaata
     6121 cgctttatta tcattgttag ttgtagtagt agtgatagtt gccttatgta taggtgacaa
     6181 tgcatttatg aaagatccag agactggttc tatactatct agtaatgcac ctttaatgaa
     6241 aggtatagtt cctataatca ctattatatt tttaactcca ggattagtgt atggaaaagt
     6301 aagtaagaag ataaaaagtg acaaagattt agtatctatg atgggtagta gtatgagtga
     6361 tatgggtgga tatatagtcc tagcatttat agcatcccag tttattaatt tatttaatct
     6421 tagtaactta ggaacaattt tatcaataac aggagcaaaa ttactagcag agtcggggat
     6481 acctagctat ggattgataa taggatttat attgctatct ggatttatca atttatttgt
     6541 aggaagtgct tctgcaaaat gggcgatttt agcacctata tttgttccca tgtttatgct
     6601 actagacttt aatccagcat taactcaaat agcttatcgt attggagatg cttcaacaaa
     6661 tccaataagt ccactttttc cgtattttcc agttatattg gcctttgcca gaagatatga
     6721 taaagatata ggtataggta ctgtcatatc gaatatgatt ccatactcag tggtatttac
     6781 attaatagaa ataataatat tgttactatt catgggtatt ggcataccat taggacctgg
     6841 tggaggaata tcttacgttt tatagaccat tataataaat ttatcaatga agattaaact
     6901 aataaaatat attctttaat taagaggagg attattatgt taaaaacaac aaaaatttca
     6961 gacccagagt tatacaagat tgtagctgat gagttggtta gacaagaaca caatattgag
     7021 atgatagctt ctgaaagtac agcaccaaca gaagtacttg aattaagtgg atgtgtattt
     7081 acaaataaaa cagaagaagg ctatccaggg gctcgttttc aagcaggttc tgaagaagca
     7141 gataaacttg aaaccctagc aataaaacgt gcaaaagaag tatttggagc agaacatgta
     7201 aacgtacaac cgtattcagg ttctacagct aactattgtg tatattcatc aatattaaaa
     7261 ccaaatgaca ctgttttaag tatgcgtctt gaccaaggtg gacacttgac acatggtagc
     7321 gcagttaatt ttttacatga catttataaa tatgaatttt atggggtaga cccaaatact
     7381 ggacgtatag attatgatgc tcttgaagca aaggcaaaag aatgtagacc aaaacttata
     7441 attgcagggg caagttcata tccaagatta atagattatg aaagaatatc aaaggttgca
     7501 aaagaagtag gagcttactt tatggtagat atggcacatg ttgcaggatt agtcgcagcg
     7561 aaagtaatac ctagtcctgt accttatgca gattttgttt cttcatctac gacaaagact
     7621 ttctgtggac caagaagtgg tattgtactt tgtaaagcag aacatgcaaa gaaactcgat
     7681 aaaggtgttt ttccaggaac attagggtct atacatctta atacagttgc agcaaaagcc
     7741 ttttcactat tatatttaag tacagataaa tttaaaaaga taatggagca agttgtagta
     7801 aatgctcaga ctctagcttc tgaactgatt tcacatggtt ttagtattgt aagtggaggt
     7861 actgataatc atatagtaat ggttgactta agaagtaaga atcttacagg aaaacaattt
     7921 gaaaaagctc ttgaatatgt aggaataaca gttaataaaa atgttatacc tgacgaccca
     7981 caatcaccat ttgtaactag tggtgttcgt ataggtctta catcaatatc tcaaagaggt
     8041 ctgaaagaaa aagaagttat acagatagca ggaataatga ataaggtagc agaaaatatt
     8101 gataataaag aagtattaga tgaatgtaaa gcagaggcac aagaacttat atctaagttc
     8161 ccattatatc cagaagggta ttttgaagat taaatatttt gatttgtata gctcacaatt
     8221 tataaagcct gtaacataaa atttaataat atataaccac tataaggtgt tgattaatca
     8281 acaccttatt ttttttgaaa agtaatatac aagctatcat aagcatataa ttccttatag
     8341 ataattaaca agggggataa agttatgagg tattataata aacctaccaa agaagtatta
     8401 aaatacttaa aaacaaatcc agaaattgga cttgatgata atgaagtaga agaaaggaag
     8461 cttagatatg gattaaatga atttactata aaagaaggta gaacattttg ggacgagttg
     8521 ggagaaagtt tgacagaacc tatgatatta attctcatag gagcagcagt aataagttct
     8581 tttgtgggag aattacatga tgcattaggt attttagggg ctatttttat tggaatttct
     8641 ataggcataa taactgaagg aaaatctaaa aaagcagctc aggccctgtc aaaattaaca
     8701 gaaaatatag aagtaaaagt acttagaaat ggaaagataa ttaaaatatc aaaaaatgat
     8761 ttagtaccag gagatattgt atatatagaa actggagata tgataccagc agatggaaga
     8821 cttatacagt ctataaattt gaaacttaga gaagatatgc taacaggaga atctgatgat
     8881 gtagctaaga atgctgatgc tgtattagat atggaagtag tttattctaa aacagaaata
     8941 atcgaacagg atgcaatacc tgcaaagcaa gtcaatatgg tatttggagg gactcttgta
     9001 gcatatggta ggggcataat ggttgtcact catactggtg ataagacaga gatgggtaag
     9061 atagcacaga atttatcaaa tgaagaccag caaactccac ttcaaattaa attagggaag
     9121 ttgggtgcta aaatagcagg aatatcaggc gtaatagcta ctttattgtg tatgtttatg
     9181 attatacaga tgcagagaaa aggtatgtta attttagata caagcagtat attatctttc
     9241 ttacaatcat tagaacctgc taaaaatgca tatatggttt gtattgcatt aatagttgca
     9301 actgttccag aaggtttgcc aactatgata aatattacct tagctataac aatgcaaaag
     9361 atggcaaaga taaatgcatt agtaacaaag aaagaagcct gtgaaactat aggttctgtt
     9421 tctgtaatat gttccgacaa aacagggact ttaacacaaa acaaaatgat ggtagaggta
     9481 gcatatgttg atggtaaata tataagtgga ggagagtatc aaagtaacag ctattttgaa
     9541 caaaactgta tagtaaattc aactgcagat atagaaaaag aagataattc atttaaatat
     9601 ataggaagtg caacagagtg tgcattactt ttatatcata atgataagaa ctataatgaa
     9661 atgagaaaac aaacgtattt gatatcacaa ataccattta gttcagaaga aaagaagatg
     9721 tcaacattaa ttcgtcaaga ggattcagat atattacttt caaaaggtgc tccagaagta
     9781 ttattaaaaa aatgttctta tgtacaacaa ggaaaaaata ttgttccaat aactccaaaa
     9841 gtagaaaaaa gtattttaga tgagattaag aagttacaaa ttaaatctat gagaacatta
     9901 ggatttgctt ataaaaaaat gagtaattct aaaacagaag ttgcaatgac ttcagaaggt
     9961 gaattgaatt taataggaaa ttcaagaagt tatatgaagg aagataattt agtttttagt
    10021 ggatttgtag gaatagtgga cccattgaga gaaggggtca aagattccat tgataaagca
    10081 tttaatgcag gagtagatgt aaaaatgctt acaggagata atataaatac agcaacggct
    10141 attggaaatg aattaggatt attaaatgat gggaaaaagg cagttgaagc aacatatata
    10201 gatgtattga cagataaaga actgagagaa gaaattaaag gaatatctat tgttgcaaga
    10261 agtaaaccag atacaaaaat gagaatagtt tcagcgcttc aaaaaagtgg cgaagttgta
    10321 gctgtaacag gtgatggtat aaatgatgcc ccagctctta gtcaagcaga tgttggaatt
    10381 gcaatgggta tttcaggaac agaagtatct aaaaatgcag cagatataat attgactgat
    10441 gatagcttta gtactatagt agagggaata aaatggggaa gaggtatata tgagaacttt
    10501 caaagattta tacagtttca gcttactgta aatatagtag catttataat tgctataata
    10561 tctcaactta ctggtaagga tatgccattt actacaatac aattattatg ggtaaatata
    10621 ataatggatg gtcctccagc cctagcatta ggattagaac ctgttagaga ttatgtattg
    10681 aaaagaaaac caataaatag acattctgga ataatagcta ggtctatgtt tgtaaatatt
    10741 attataaatg ctattcttat aattacaatt gtatttactc aatcagcttt taatatattg
    10801 ggagctacat cagaagaaca aggtactgtt atattttctt tatttgcgtt cagtgccctt
    10861 tttaatgcat taaattgtag agaatttggt ttaaatagta caataccaaa tttctttaaa
    10921 aataaactgg cattgcaaat aatagtagtt acagggataa ttcaaataat atttacacaa
    10981 gtgttccaga gtttctttaa ttctgtttct ttggactttg atatgtggat aaaaataata
    11041 ctatttgcat ccactatatt attgtcaaat gaatttgtaa agctaatact tagaacaatg
    11101 aaaaatagta gaagtatgaa ctctaatagt aaaaattaat tcttatgaaa ccgcaaagta
    11161 ctatatattg taactttgcg gtttttgttt gtttaatgtt gttttatatt accattttca
    11221 tatttaattt tttattaatc tgaacacaat cttccattgt aattgcttca tctgtgtcaa
    11281 cacgttcaaa gtcaatatct aacttttgta atattttgta tacctctttt tgcaatggag
    11341 tatcaaattt aataggtgat tttgtgtaaa tatcactgat aaaaaacatg atttatttca
    11401 ttcctttccg tttaaaatct tatagttata gtgtatcata aggttataaa aacataaata
    11461 tagtataaat ttaaaatatg taaagacaaa acaaaaaaat catattctaa gtaatacttg
    11521 ggaaaaatga tattatcata ataaataatc tttgtaaaaa cttatataga atctattaaa
    11581 cagacactaa gccataaaaa ctttacgaaa tataaaattt gtatctaaat agatatatag
    11641 aataatattt tactgaagta gagtgatttt taagaatttt atatataaat tatgttatca
    11701 taaataaaga tatagattat aaaatttgtt aataaaataa agggcaggga ggtaagtttc
    11761 atgttttcca aaatcctagt caaaacattt atcagagata gcgaaaacgt tcaaaataca
    11821 gatgttagaa ataagtatgg ttatgtagct ggtgtagtag gtatattgtc caatttactt
    11881 ttatttgtga taaaggtatt cataggaatg ttcacatcta gtatagctat aatggctgat
    11941 gcatttaata atctttctga tatggcatct tcagcaataa ctatgatagg ttttaaatta
    12001 gcaagtaagc cagctgacaa agaacatcct tttggtcatg gaagaataga gtatttatca
    12061 gcattaatag tagcatttat ggtgatgttg gttggacttc aatttgtaaa gtcatctata
    12121 gaaaggatag taaatccaat tcctgtaaaa tttgaagtaa taccacttat acttttaatt
    12181 gtatctataa tgattaaaat ctggttgagt cgttttaata aatttgtggg aaataaaatt
    12241 gattcttcag ccttaaaagc agtttcactt gatgctttag gagatgtatt tacttcaagt
    12301 tgtgtagtta tatcatttat tgtagctaga tttactaatt ttcctataga tggatatgtt
    12361 ggtatcgtag tatcattagt gatactttat gctggtttct ctcttgtaaa agatactata
    12421 aatcctcttt taggagaagc accggatgaa gaaatggtaa attctattat agagctattg
    12481 ttatcttata aatatataat aggtacacat gatttaatta ttcataacta tggagttggt
    12541 agatgtattg catctataca tgcagaaatt ccatccaaca tagatataat ggaaatacat
    12601 gaaattatag atactgcaga gagagaaata tctgaaaaat tagatatata tctagtaatt
    12661 cacatggacc caatatgtct tgaagataaa gaagttatgt cagccaaaaa agaacttgaa
    12721 gaaatactta agaaaaatag tcttgtaaaa tctatgcatg attttagaat agttggaaaa
    12781 ggaagcaaga agaatttaat atttgatata gtagttaatc cttccgaatt ttccaaagac
    12841 atgtcagagg atgacttaaa agaagatata acaaaattag ttaaggagat aaatcctgaa
    12901 tataattgtg taattgttgt agataaggat tttatttaat tattaattaa tctcataaaa
    12961 ggtaaaaaat gtaaaaaaga tagacaatag tatagaggca taatataata gaagtatata
    13021 attgtatttt taatataaat aaagcaattt taattgtttt tatgaaatat tatagagatg
    13081 ttgaagtata ttctattatt gggcacctta tggatatact gagtcagtgg tgcaaccggc
    13141 tatgaatata aatttattta ttttcatagc tttttttata taatttttta gtaaaaatta
    13201 atttatatac gatattaatg gaagattata aactatagat aacctagagg gggaaaattt
    13261 atatgaagaa aggaaataaa aaggcattat taattagttt aattatgatt ttaagtatgg
    13321 tggtgtctac aatatatcca actgtatctt atgcttcaga attaggagag aatagtcaga
    13381 ttcaaagtgg ttcaactaat tcatcaactg gagaggagaa ggaaagcgac aataaaaaac
    13441 cagaacagac tccagagaaa gataaggcaa cagataataa aaaaccagaa cagaccccag
    13501 aggaagataa ttcaacagat aataaaaaac cagaacagac ttcagaagaa gataagtcaa
    13561 cagataataa aaagccagag caaactccag aaggagaaaa gccaatagat aataaaaagc
    13621 cagagcaaac tccagaagga gaaaagtcaa tagataataa aaagccagag caaataccag
    13681 aagaagataa gtcaacagat aataaaaagt cagaacaagc tttagaagat gaaaaaccac
    13741 tagacaataa aaatacagaa aaaactccag aggaagataa tctattagaa gatgaaaatt
    13801 tattgaaagt tttagaagaa gaacttaatg aagactatgg atttgttgta aaaattaata
    13861 acaatacaat agaaacggaa tcaatgaaaa aaatatcatt taatttaact tatactccaa
    13921 catcaaaagg aatacaagca ggagattcaa taacttttaa ggtgccagat gtattcaata
    13981 aagttaattt agattataca agtgaatgct ttgataaaac agaaagtaat ggagagtata
    14041 cacttacatt tagagaatta cctaatggcc aaagtgtaat gcaaggtaaa ataggtttgg
    14101 aagcatatgt taaaaaggtt gatgaagata ctaatgcaaa aatacatatt gaaaccactg
    14161 gaaaaataga aagtggaagt ggagatatag atgtagaaat aaaacctgga gataaaacgg
    14221 atgttccaga tgctaaagga acacttaaaa agcttgttga aggaagaaaa tcaactactg
    14281 tatttatgcc agttaaaaat aaagatataa attacagtat acaagtaaat gaaaagcagg
    14341 aagagttaaa agatattatt ttgtatgatg agcttcctga aggattgaca ttgataaatg
    14401 gttctgtaag tgtagtaaca agtgatggaa aagaagttag tgattttaat attgaacaga
    14461 gtaaaaattc tatttcagtt aattttggaa atatagataa atcgtatact gttaagtata
    14521 aggctagaat cagtgacaaa aatgcaaaac atggtaataa atataagaat gtagctagga
    14581 ttgaatctga tggtaagaag atacaagaag atgatgctac tgtaagtata tttgatagag
    14641 gagataatta tcttcttact aaaggacatt caggagcaac aaatattact caagttggtc
    14701 aagtaataaa ctatcagatt tcaataaatg atgataaatc accaataagt aatgttgtta
    14761 taacagataa tataccagaa ggtatgagat tgactacttc aggagaggat gggcatgatt
    14821 ttagagttgt agaagttcca atgaatggga gctggactcc ttggagtaaa gaaaaaattg
    14881 ccaataatat ttcatataaa gtagaagaaa aaagaaatga aagtgggcaa gtagataaag
    14941 ttataactgg atttacaatt aatctcagta aagaagaagt agaatcaaag ttttttatag
    15001 cttatacatt aaaggtaatt agtattgaag atagttatat aaatagagct gtccttgatg
    15061 caaataatag tgaaattgat aaaaatgatg agataaactt taagaaaaat tctggattaa
    15121 taagcgcaaa aaaagaagtt gataaaaagg ttttaaatag tagtgataac cagattgtta
    15181 aatacaaaat caatatgtca acttatgggg tttatgatgc aggacaagta aatcttttgg
    15241 atgaagtaaa cccatctcta aaaatatcta atataaaata ttctgataat cttgaactta
    15301 aaaaagaagc tggagatgga aaaaatacaa taagattagt aaataaatac gaatttaaac
    15361 agataaaaga aggggaacct gtgcaaagct gggttacatt tgatgcagac ttcacaaatg
    15421 taaaagttgg ggagactata caaaatgtgg ctcagattaa tggttcaagt cctccgggag
    15481 tagagactac taagcaaggt tatgcttttg aagctaaaaa agtggatgct ttagataaaa
    15541 atgtactttc aggtgctaag ttcaatttag aagatgcatt tggaaatata gtagttaagg
    15601 atttagttag tgatgaagat ggtgtaattc aatctagtgt aaaaaaacca ggaatatatt
    15661 atttagtaga agtgatggct ccaagtggat atgaaaaact gaaggataaa attaaggttg
    15721 aaattggtaa taaagatatt ggtagaatag tagatatcgg aaatatagaa aacataagac
    15781 aagaaaatcc accagtaaat ccacctgtac cgccaaatac agatgaacca atagtaaatc
    15841 caccagtgcc accaagcaca gataaaccaa ggaaaccatc aaatccatct gatacagagg
    15901 atactatagt tataaatcca ccagtaccac cgtcagaaga tataataaat cctccaatac
    15961 cagagatatt gaatccacca gtaccaccat cagaagaggt gatagaaact cctgttaaac
    16021 agattgttcc aataccagaa gtggtaaagc catcagtgtc agaagaaaaa aataataaag
    16081 ctaaagatga tactttggta aatccaccag taccaccaaa aacaggggat agtactacaa
    16141 ttattggaga aatactttta gttataggag ctattgtagg acttgtcgta ttaagaagaa
    16201 ataaaaatac aaattagacc ctaacattat aaaaaatata agttatatta aaaaatatct
    16261 tctaaaacaa tatttaataa tgaaaatatt gttagaagat attttttttt gaagatttat
    16321 gtaaaaaaat aataactttt tagaaaaaag ttccaaaggg atatagacaa ttaaaaagat
    16381 ataagctata atatagatat aaaattaaat gaggcaaaac tagggaaacc tagtcacgca
    16441 aagctatagg ggctaaagtt tagtaaacca tgccagccag ttgccgaaaa gagtaaaaat
    16501 ttctttttgt atatacaaag atactcttgg gtatcttttt tattttgaaa tttattactc
    16561 ccggcctaac tcaaaggagg gaataatatg agaccaagta aaaaattatt aatagctata
    16621 atatcaatat tcttaataag ttcagttcca gtaagtgcac atgcatatag tactactata
    16681 caacaaaata aagacacact tagtcaaata gtagtttttc caactggaaa ttacaataaa
    16741 aacgaagcta atgctatggt aaatagatta gctaatatag atggaaagta tttaaatgta
    16801 ttaaagcaag ataacttaaa aataaaatta ttaagtggaa agttaacaga tgaaaaagaa
    16861 tatgcttatt taaaaggtgt agttcctaag ggatgggaag gtactggaaa aacttgggat
    16921 gatgttccag gcttaggtgg aagtacagta gctcttagaa taggatttag taacaaaggt
    16981 aaagggcatg atgcaataaa tttagaatta catgaaacag cacatgcaat agaccatata
    17041 gtattaaatg atatatctaa atcagcacaa ttcaaacaaa tatttgctaa agaaggtcgt
    17101 tctttaggta atgtaaacta cttaggtgta tatccagaag aattttttgc agaagcattt
    17161 gcatattact atttaaatca agatacaaat agtaagttaa aatcagcttg tccacaaact
    17221 tatagctttt tgcaaaacct agctaaatag agctttaata aatttaaaat aaatataaaa
    17281 gagatgctat tataatagca tctcttttat attgcgttta aatctaataa attttgtctt
    17341 atgtataact tgatagatta tcaattacta ctccttatac aaggcttcaa cgtgtttatt
    17401 atgcatttga gtaattatcg taggtataat agaaattatt gaaccaatta ctatcaataa
    17461 aattcctata accatgttta tagggataat ttctttaagt attaataatg ctagtattgg
    17521 agatagtact ggtttaaaga agaatactaa agatgtaaga ctagtagatg tagcttccat
    17581 tgccataaag taaagtgcat aaccaacacc tgtaacaaat acgaatacat aaatcataat
    17641 gggcatattg tgtaaggtat atccactaaa aatagggata tttgcaaata tatgaagttt
    17701 atttttattt aatatatctg cgataaaatt aattttagtg agtaaaacca atatcaacat
    17761 ttccaaacta ccaaatataa agctaaagca agttacaact attccaccaa attttaaggt
    17821 ttttctttta ccaaatacag tatacattga aaaaataata gcagaagata atgttaagaa
    17881 tattccacta agagttagtt ttgtatgcaa tggatttatt ataactataa ttccaagaac
    17941 ttctaatata agtgaaatta cattgtgcct atatattttt tccttcaaaa ttaagtaagc
    18001 taaaagcatt acaaagactg gattacaact gaacaaaaca gcaactacag atgcctttgt
    18061 gtttagaaca gccagttgat acaatgacat acttactact acacacataa aacctaaaaa
    18121 tgcaaagtat tttaagtctg attttgtaat agaaagacta agagctctta atctttttac
    18181 agcaaaaggt agtaagacta aaccgccaac aaaaaatctt gataaagtta tttgtaaggg
    18241 attaaagtca ttagtgacag tttttagact aatttccatt gaactaaaaa ataaggtagt
    18301 cagtattata taaacataac cttttttcaa gtcaaacacc tccttgtaat ttatattagt
    18361 actatagata agaatattca agcatattgg aataatatgg tatgtataaa atatagtaca
    18421 taaaattata aactacctta atatagaatg taagtattct atactaaggt agttaattat
    18481 ttgaattact ttgatttagt tattttaaat tatataattt ggctaatttt tcaaatgctg
    18541 gtaaagaact tttaacttta tcataagata cacaatatga tactctaaaa tgacctggac
    18601 aaccaaaaga agaacctggt actaataata aattaaattg ttttgcatca ttgcagaatt
    18661 ttttatcatc ttcaattgga gcttttggga acaaatagaa tgtaccatta ggtttaacac
    18721 aagaatatcc catatcgatt aaactattat atagaaggtc aaaattcttt ttataaatat
    18781 ttacatcaac ttctgcatct aaacttcttg caataaccct ttgaaaaaga gaaggagcat
    18841 ttacaaatcc aagtattcta tttgcaacat ttaatgaaga cataacatca tcaaaatcat
    18901 ccatttgccc attagcaaca atatatccta tacgttcacc aggtagagat aatgatttac
    18961 tataagagta ccctataaat gaatttctat agtattttag tacacaagga actttggcac
    19021 catcataaat tatttctcta tatggctcat cagaaattag atatatgctt gtattaaatt
    19081 ctttttgttt tgaatccaat aattctccaa gattttttaa taattcttca gaatatatga
    19141 caccagtagg attatttgga gtgtttatta ttaaagctct tgtttttgga gtaatagcat
    19201 tttttagagc atctaaatct ggttcaaaag tctctatatt tgtaggaact tctattaatt
    19261 ttccatcata gttttctgta taatttttat actcaccaaa atacggtgca aaagcaataa
    19321 cttcatcacc aggatttaaa agagttttta aaataatatt tagaccacca gcagcaccac
    19381 aagtcataat taaattttct cttgtaagat ttaatccatc ttttttattt atatgttcag
    19441 caatagcatc tcttacatcc tcatatcctg agttgttcat atatccatga actaaatttg
    19501 gagattcttc atttaaaata tcatttataa ctgctttaat agtctctgga ggttcaacac
    19561 ttggatttcc tatactaaaa tcaaaaacat tttcctcacc ataaatatca gaaagtttct
    19621 ttccttcttc aaacatagct cttataacag aactatttgc aactaaagtt tgcattttat
    19681 tagatatcat atgtaacact cctttttata gatttatatt gcttatgtat atattaccat
    19741 atttttactg aatttagaca attttcgaaa aattacttgt ttgaaaatat aaacttttat
    19801 ataaaatata tttatgtaca gtgcatatta aaaattccaa tttctaattt tatcatgatt
    19861 attttatata atagtttttt aaagaattaa taaaacatag atttagagaa taaaatattc
    19921 ttgactatat taattgttta atataatata gttgatatag tcaaacatat tataattata
    19981 gaagggaaat ttaagatgga ttttaaaaat ttacagtatg aaagtttgtc atatattatt
    20041 tgtaacttgc aaaaaaactt taaactttat tgtgaaaaat gtttaaaacc atataaactt
    20101 acgaatggtc tatatttcta tttaatttat attaataaaa ataggaattg ttctttgaat
    20161 gatgtttcta cagaatttga agttgataaa gctcatacaa caagaactat atctaggtta
    20221 gaacaagatg gatacataga aaaaatccaa aaccctaatg atagtagagc ttttcagttg
    20281 agagtaacag ataagggtga ggaagtatta ggggatataa aaaacatatt ttcaaagtgg
    20341 gataaccaca taaaaaaaga gttctcagat acagaatata aagaactggt aaagaattta
    20401 catgtggtaa aggatataaa aacagctgtg gaggaaggat aggatgtatt gtaatttatt
    20461 aaaaccaatt aaaattggaa atttggaatt aaaaaataga gtatcttttg cacctacaag
    20521 catgggtctt aaattggaag aaaaaattaa aaagttttct gatattgcta agtcaggagt
    20581 agctctgatt actctaggag atgtatctat tagacctagt tttcataagg tagctataag
    20641 cctatcggat gaagatggag tcattaaata caagaaaatt gtagatgaaa tacacaattc
    20701 tggtgcaaag gtatcagcac aactattttg ttcagattat gatgttaatt taattaaaga
    20761 tactatgaag atgggaatta cttcacatga tgagataaaa aaaataatga atgacggagt
    20821 aaaagattac ataacaaata tgcccaaaga agaaattaaa aatattataa atttatttaa
    20881 agtaacagca ttgaatgcaa aaaaagcagg ttttgacatg attcaaattc atggtgatag
    20941 gcttgtagga agtttttcat caagtatatt taataataga aatgatgaat atggtggaac
    21001 gtgtgataat agaagtagat ttgcaagcga aataattagt agtatccgag atgaagttaa
    21061 ggacattcca atagactata aatttgcaat aagacaagaa aatcctcatt atggaaatgc
    21121 aggagtttta ctttcggaag ttgagtattt tgttaaaaaa tttgaatccc taggtgtaaa
    21181 cagttttcat gtaacacttg caaatcattc aaaattagaa gatactatac caaccaataa
    21241 tcatccttac tttaaagatg aaggctgttt tttatattta gctgatgaag taaagaaaca
    21301 cacaaatctt ccagtatgtg gggttggaaa attgtctagc ccagatttta tagaaagtat
    21361 tatttcaaat aatagagtag atatggtttc tatgtcaaga caattactag cagatagtaa
    21421 ttggttacag aaagtaaaag atggaagagt agatgagatt aaaaagtgct gttattgtaa
    21481 taagaagtgt gcagatgctt tacaaacacg ctctcagttt ggatgtatac tagattagaa
    21541 tatctttata aaaataaata atttgttaag gttaatatat ttttggtgat ttagataagt
    21601 atttagataa agaggaggag acatcatgaa aagtttagtt ttatattcaa gtttaactgg
    21661 aaatactaaa aagattgctt atgctatata tgatgaaatt caagaagaaa aagacattaa
    21721 agatgtaaat gaa
//
LOCUS       DAEQJM010000061        20363 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.061, whole genome shotgun sequence.
ACCESSION   DAEQJM010000061 DAEQJM010000000
VERSION     DAEQJM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20363
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.061"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(16..366)
                     /locus_tag="KRQ43_002846"
     CDS             complement(16..366)
                     /locus_tag="KRQ43_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2743191.1"
                     /translation="MKKIVLKDILFLVTTLSIIVILLFVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKNTAFKTTILSTGKSDCILIEIGDKFIMIDTGEDKNGEQIVDKL
                     KEKEINALDYLIKK"
     gene            complement(500..1996)
                     /locus_tag="KRQ43_002847"
     CDS             complement(500..1996)
                     /locus_tag="KRQ43_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH2743192.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACISACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFEFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            complement(2254..3744)
                     /locus_tag="KRQ43_002848"
     CDS             complement(2254..3744)
                     /locus_tag="KRQ43_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH2743193.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            4211..4411
                     /locus_tag="KRQ43_002849"
     CDS             4211..4411
                     /locus_tag="KRQ43_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH2743194.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
     gene            complement(4591..5469)
                     /gene="speB"
                     /locus_tag="KRQ43_002850"
     CDS             complement(4591..5469)
                     /gene="speB"
                     /locus_tag="KRQ43_002850"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBH2743195.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(5459..6310)
                     /gene="speE"
                     /locus_tag="KRQ43_002851"
     CDS             complement(5459..6310)
                     /gene="speE"
                     /locus_tag="KRQ43_002851"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBH2743196.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            complement(6340..6753)
                     /gene="speD"
                     /locus_tag="KRQ43_002852"
     CDS             complement(6340..6753)
                     /gene="speD"
                     /locus_tag="KRQ43_002852"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBH2743197.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            complement(6840..8315)
                     /locus_tag="KRQ43_002853"
     CDS             complement(6840..8315)
                     /locus_tag="KRQ43_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH2743198.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            complement(8953..9606)
                     /locus_tag="KRQ43_002854"
     CDS             complement(8953..9606)
                     /locus_tag="KRQ43_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2743199.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKFMRENDLENVERVLREHWKTIPIAEMKKEKLL"
     gene            complement(9851..11716)
                     /locus_tag="KRQ43_002855"
     CDS             complement(9851..11716)
                     /locus_tag="KRQ43_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase C-terminal domain-containing
                     protein"
                     /protein_id="HBH2743200.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDIPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVDENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(11721..14141)
                     /locus_tag="KRQ43_002856"
     CDS             complement(11721..14141)
                     /locus_tag="KRQ43_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HBH2743201.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNIDNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYEQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(14155..15597)
                     /gene="glgA"
                     /locus_tag="KRQ43_002857"
     CDS             complement(14155..15597)
                     /gene="glgA"
                     /locus_tag="KRQ43_002857"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBH2743202.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNRDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(15626..16756)
                     /gene="glgD"
                     /locus_tag="KRQ43_002858"
     CDS             complement(15626..16756)
                     /gene="glgD"
                     /locus_tag="KRQ43_002858"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HBH2743203.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGS
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(16758..17918)
                     /locus_tag="KRQ43_002859"
     CDS             complement(16758..17918)
                     /locus_tag="KRQ43_002859"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBH2743204.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKRSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            complement(18689..19732)
                     /locus_tag="KRQ43_002860"
     CDS             complement(18689..19732)
                     /locus_tag="KRQ43_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBH2743205.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(19753..20199)
                     /locus_tag="KRQ43_002861"
     CDS             complement(19753..20199)
                     /locus_tag="KRQ43_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBH2743206.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
BASE COUNT         6412 a         3654 c         2048 g         8249 t
ORIGIN      
        1 cacgagtgtg cgtagctatt ttttaatcaa atagtcaagt gcatttattt ctttttcttt
       61 taatttatca actatttgtt ctccattttt atcttctcct gtatcaatca ttatgaattt
      121 atcacctatc tcgattaata tacagtcaga ctttccagta cttaatatag tagtcttaaa
      181 tgcagtattt tttgtgctcc tctggatacc attttgcctc acactatttt tgtcactttt
      241 taaataagat tcacttgttg attttatctt actattagta gttatatttg ttacaaacaa
      301 taatattact attatagata atgtagtaac taaaaacagg atatctttta atactatttt
      361 cttcatccaa aagctcctat aaattttatt tattacatat ttatagtata gcaaccttaa
      421 ctctgtaaaa tacacatata aaaagggaaa attttaggca tatttgtggc atgataaaaa
      481 aatgactgta ccaaaacaat tatctttcta aatttacatc ttcaaattct ttaatcttat
      541 cattagataa aacactcttt ttagtagatt gtccattttt tctatcaaaa gtatttttag
      601 cttttacacc tgataaaaac ttacctgctc cattaataca accttcttca cacatcattc
      661 cttctataaa attaccttct aatcttccca atttagccat tgtcattgtc tttttaattt
      721 gtcttggacc agatactttt ataggttcaa actcaaaact aagtcccttt tcagcaatat
      781 agttctgtac tgatttggca agtccaccag acgctccaaa tccccttcca aaaatcgaac
      841 catcatttat atcttcattt gaacattttg ataaatctat attaaatgct tcaaataatg
      901 ccattagttc ttcaaaagta agtacataat ctactgaatc ttttaaactt ttctctgttg
      961 cctcactctt tttagctgta catggcccta taaatacaac tttagcatca gaatctattt
     1021 tttttactaa tcttcctgtt gctaccatag gagacactgt agatgatatt ctatcttttt
     1081 catctgggaa catcttctct atatacttaa aaaatcccgg acaacatgaa tttgtcatgt
     1141 aattatctcc tgattttatt ctttcaataa gctcattgct ttcatgaact gtaactgcat
     1201 ctgctccaca agaagcttct atcatatcta caaatccaag tgattttata gcatttttta
     1261 actgaccata tgtaatatta ctatctattt gacctgttat agctggagct actattgcat
     1321 acatattttc tttctttgca agtttttttg caacaggtgc tatcaaactc ttatcagata
     1381 ttgctccaaa aggacatgct gatatacatg ctccacaatt tatacaatta tcttcatgta
     1441 tcattgcttt catagtgttt ctattaaaat ccaaagctcc tgttggacaa acgcttttac
     1501 aaggtcttac aacttctgat atagcatcat attgacatga acttttgcac attccacaag
     1561 ccttacataa atcatgattt atatatgctc tcccatttat ataagaaatt gccccaaatt
     1621 tacatgcttc cttacatcta tgagccaaac accctctaca aagctctgta actgtaaatt
     1681 catttattgg acatctatca catgctgctt caactatata tataatttgc tcatctgtgt
     1741 ccaaactaac tgaatctgga tttatatctc catatttact atttggagtt aaacttaatg
     1801 caagttgcgc cctttcaaga actacttctc tctctttata aacacaacat ctatatctcg
     1861 ccttttctcc tttaattatt tcatatggaa ttttttctat attttctttt gttaaatttt
     1921 cttcaataga tagtcttgct actgctgtta aaacttcatg tttcaacctt tttagttgcg
     1981 tttcaaattc aaacataagt aatcctccct ataaatcaca cctttttact atatttctac
     2041 tattatgtat attgtatttt ttatttattt ctataaatta ttataacata ggcatatact
     2101 ttgttaagtt atatacaaaa tattatatat gtaattttta ttttagttgt tcattaatta
     2161 aatatataaa taaaaataga gttgtccaaa agttaaacct caacttagaa caactctatt
     2221 aacaatatgt atttttgttg ctttgtatta tctttatttt tctaaattta tattactaaa
     2281 atcttttatc tttgtatttg ctaagacact tttcttagtt gattgagaat tttttctatc
     2341 aaaagtggct ttaacctttg cacctgataa gaatttacca gaaccattta tacaaccacc
     2401 ttcacacatc attccttcta taaaattacc ttctagcttt cctaaattag ccatagtcat
     2461 agttttcttg atttctcttg aaccagaaat ctttacaggt tcaaaattaa caccaatacc
     2521 tttttcagca agataatttt ctatagcttt tgtaagacca ccagcagctc caaaacctct
     2581 tccaaaaatt gatgcatcat ctatatcttc atttgaacac ttagccaagt ctatatcaaa
     2641 tgcctcaaat aatgccatta tttcttcaaa agtaagtaca taatcaacag ctccttttaa
     2701 ttctttctta gctgcctcac tctttttggc tgtacatggt cctatgaata caactttagc
     2761 atctggttca tgacttttta taaatctacc actagctatc ataggagaca ctgtagaaga
     2821 tatttttcct acatgatttg ggtatgtttt ttctatataa ccaacaaatc ctggacaaca
     2881 agaatttgtc ataaaagcct ctcccttttc cattctttca gcaaattcta agctttcatg
     2941 aactgtaact gcatctgctc cacaagctgc ttctaataca tcaacaaatc ctagtgattt
     3001 tatagcattt tttatttgac catatgtaac atttgcttca acttgacctg ttatagctgg
     3061 agctactacc gcatacattt tctctttttg aaccaacttt ctagctacag gagctatcaa
     3121 actcttatca gatattgctc caaatggaca tgctgacata catgctccac agtttaaaca
     3181 tttatcctca tgtatcatag ctttcatatt ttctctatca aatcctaagg cattagttgg
     3241 acaaacactc ttacatggtc taacaacctc tgagatggca tcatattgac aagctttttt
     3301 acacattcca caagccttac ataattcatg atttatatag gccattcctc cgacatgtgt
     3361 tatagctcca aatttacaag cttctttaca tctatgtgct agacatcctc tacaaatatc
     3421 tgttactgta aattcattta ttggacaact gtcacatgca gcttccaaaa tatatataat
     3481 ttgttcatct tcttctatat ccattgtatc taaatctatc ttatcttgac ctggttgtaa
     3541 ccccatactt acatttactc tctcagatat tatagctctt tctttataaa cacaacatct
     3601 gtatgtaggt ttctcacctt ttattatttc atactgaata ttatccattg cttctctggt
     3661 aaggttatct tcttttccaa gtctagctat tgcagttaaa acatcatgtc ttaatttgtg
     3721 tatttgtgtt tcaaattgaa acattttaat accacccccg taaatgattt tatacgatac
     3781 cattataaca caatatgtcc ttttattaat atatacataa aatattatat gtttaaattt
     3841 tattttatcg aatatatata gtgttttttt attttattat ataatattat tgatatttct
     3901 gaaatttcac tatttttatt tttacttttt aatctaatat ataatatttt ttattatata
     3961 ttttaatttt actttttact tacatacctt tttgttgcat tttttgacat taaatttatt
     4021 atctacattt acattttcgt caaattttac aatacttctc actgtataat ttaacaattt
     4081 ttattaaatt ctaaaagtaa ttaatttttt taaaaatttt atttgctttt atttaaaatt
     4141 tatgttatat taatagaaca gacttatttt tttagtttgt attttttaat aatgcggagg
     4201 ttttcttata atgaaaaacg gaatagtaaa atggtttaac aatgaaaaag gatttgggtt
     4261 catatctgta gagggagaag atgatgtttt cgtacatttc tcagctatac aaaatgatgg
     4321 atacaaaact ttagaagaag gcgaaaaggt tagctttgat ataactcaag gtaatagagg
     4381 acctcaagct gaaaacgtaa atagaatata attatttaat ttaaatatat atattttaga
     4441 aaaggagcta tcgagggctc ttttttgttg tttattatat ttatttttaa ttacaaaaat
     4501 aagaagttac tttagaaaag cgtcaaactt aaactaactt ttttaaaata acttcttata
     4561 ttataatata tactatttat ataaaatact ctatttaatt ttatcagata ttattaagca
     4621 taactctctt aagattttac aagctataac tgtcgataca cctgttgtat cgtaatcagg
     4681 gcttaactct acaatatcac aaccaactat atttatatta gagtttttta taatcttaaa
     4741 aatctcttga aactctctat aatttacacc accaggttct ggtgtacctg ttcccggaaa
     4801 cacagatgca tccaatacat ctaaatctat agttagataa atattctttc catttagcat
     4861 attaactata ttttcaaacg tatctattcc tcctatttcc atgtatgtgt gtttttcttc
     4921 tgtagcaaat ttaaattctt cttttgtccc agaccttata ccaaattgaa atattttatt
     4981 atcacctaca atatcccata ttcttttaat tactgttgca tgagaatttt tactattatt
     5041 atattcttcc ctcaaatcag tatgggcatc aaaatgaatt acatatatat cattgtactt
     5101 ttcatgtact gctttaaagg ctggtaatgt aactaaatgc tctcctccaa tcataaaggg
     5161 tacctttgaa tctctaacaa tcttatatgt ctcttgatag atttctttta agacttgttc
     5221 tgtacttcca acactaattt ctaaatctcc ataatcacat atattataat cctctaagtc
     5281 caaatctaaa aaaggactat atgtctcaag accgtaaaat tcttttctca tagagctact
     5341 tgcaaatcta gccccaggtc tgttagaagt agttccatca aatccaacac caaatactat
     5401 aagattagat tcttcataat ttttgtccat actcataaaa gtgttcatat gatagaaatt
     5461 attcttcatc tagcatctcc ttcacgtatt gaggtaacat aaacgaacct aaatgtatat
     5521 cactattata atatttagtt tttaaactta atttctccca tccatttcta tcttgatttt
     5581 ttactggatt aagttttttt gaagcaaatc caaacaacca gtgaccagat ggatatgttg
     5641 gtatatgtgc ttgataaact tctgatattg gaaatatctg ttttaatttt ttattagctc
     5701 ttttcatctc tttagcatta aagtcaaaat acggactttc actttgattt actaaaattc
     5761 catcatcagt cagtattcta taacaatcct tataaaaatc agttgagaaa agcccttcgc
     5821 ctggtcctat tgggtcagtt gaatctacta ttatcaggtc atatgattta tcatgtgcac
     5881 acttaacaaa attaacacca tcttcaaaat ataaactcac tcttttatca tctaatttac
     5941 atgagcatat atccatatac tccttagata catctacaac cattttatct atttcaacca
     6001 tgtcaatctt ttctatttga ggataacggc ttaattctct tactgtacct ccatcacctc
     6061 cacctatgac taatactttc tttatgttta aatttgtagc cataggaaca tgagttatca
     6121 tctcatggta tataaattca tctttatatg ttaccatcat taatccatct attgttagaa
     6181 attttccaaa ttcatcacta tcaaatacat ctatcctttg aaattgagac tttccttcaa
     6241 atagatgttt atttactttt atagaaaatc ttacattttc tgtccattct tctgtatacc
     6301 aaagttccat ataataatcc tcactttctc ttgtatgttt tatactgctt ctggtttatg
     6361 agtaatctta cctaaatctt tttttgaata ttttttaatt tttgtagtta agcctcttgg
     6421 aatttctgta gactcgcttc tttcagactt taaaagttgc tctaataatt caaaactttt
     6481 ccatgggtct atatcaccac aagtaaaaaa atctgctgct gcataaccat attcaggcca
     6541 tgtatgtatt gtcaaatgag attcagcaat tataacagct cctgaaaccc cccaaggatt
     6601 aaaatggtgg aatacagaat ccacaattgt cgcttttgca tttaatgctg aatcattcat
     6661 aaaattttct ataagacgtg ggtctttaag tacgttttca tcacaattat agtattctac
     6721 tagtatatgt cttcctagtg tttcaaattt catttcaacc ccaactcctt tatactttta
     6781 ataagttcta tttgataaac tctacttaac aaacacttgc ccttgcaaaa taaagtaatt
     6841 tattttatta ctagtattct atctaagttt ttatcttgta catctgtaag atacgcattg
     6901 ctatttttta agaaaataat atactccata atttcttctg ttatcaattc tcctggagca
     6961 ataatcggta tacctggtgg atatgccatt attgattctc cacaaattct atctatacat
     7021 gaattgattt ctacactttc ctttggtgca taaaaagctt ctcttggatt aagtttaata
     7081 attggattta tttgaaccat attaaattca tttaatgttg attcttttct ataaatcttt
     7141 gcaattatag aaagtgcttt tactaatcta tctatatctg atttatttgt tccaatggac
     7201 acaagtgcca gtatattata tgaatctccc aattctactt gaattgaaaa atttttatat
     7261 aataaatcgt atacttcaaa tccagtcaaa tttaattctt ttacatttat acacaatttt
     7321 gtttcatcta taaatttaac acctttttgt ttcaatattt ctgtagataa aacttttatt
     7381 ccatcaattt tgttcaattt agattttgca tacctagata gatttaatgc ttttgacagt
     7441 tgcttttcac cattctcaac tagattaact ctagcaccat ctatacttgc cataagcaaa
     7501 taagatgctg atgttgattg tagcatattg attgattgaa gaaccttttc aaaacttaca
     7561 ttatctctat tcaataagag tgctgaagat tgtgtcaatg ctcctccagt tttatgtata
     7621 cttacagcta ccatgtcagc tcctaaactt attgcagaag gaggtaaatc taaatgaaat
     7681 ggaaaatgtg caccatgagc ttcatcaact aacactaaaa cattattttt atggcatagt
     7741 tctataatac tctcaaggtc tgcacaaact ccatagtaag ttggattaag gaaaaataat
     7801 gcttttatat tacaatcttt ttctatctct gttctaactt tttcaagagt aatatttaaa
     7861 cttataccta gtttttcatc aaattctggt tgtataaata ttggtattcc tccacaaagt
     7921 attaacgcat ttattactga tttatgtata tttcttggaa gtaatacttt ttcacctggt
     7981 tttataacac tcaaaatcat tgcatgtatt gcttgagttg tgccattcgt tataaagaat
     8041 gcctcatcag ccatatatgc ttgtgctagc aaatcttgtg cattttttat aatcccattt
     8101 ggcgcagata cattatccat agttggtgat gaatttatat ccattttcat gagactttca
     8161 cctagatatt tatttaatat agctacacct ctatttttta catgtccagg aacatcaaaa
     8221 caagctatat ctttctctga gtattccttt aacgactcta ataatggagc acactcatag
     8281 cttaattcaa ctgcatttgc aaactcgcta tccatgattt caaattcatc tcctctctat
     8341 attcaaatat ttttaatatt tattatttat tatttctatt ttttattttt acttttatta
     8401 aactcatgat atttattata ttaacattcc agcattttta caagtgtttt tttgaagtta
     8461 ctcaaaaaca tatacattag ctatatcaat atttataaac tttttatttt tttgttgttt
     8521 atattaattt ttttaaaact tagtatttat aaactttctt attttttatt attttgcttt
     8581 ttttactttt ttgagtttta gtaagctttt gagtttacta tttttaattt ataagtattt
     8641 tattactaaa cttttatatt attcttattt catatatcaa aattcttggt ttagttggac
     8701 taaataattt tcctattttt gtattttaat tttaatataa aatttattaa attttttaat
     8761 tgataaaata aattctatat ttatgatatt aaaattctat aagttcattg atttatatat
     8821 gttaatttaa atatattatt ctatcgtagt gccttagagt ttttatttgt atttaaagtt
     8881 aaatttattc ttgtttttcc tttaatattt aatagtaaaa taacaaaatt ataaaaaaaa
     8941 taaagagaaa ctttataaaa gcttctcttt tttcatctct gctataggta tcgttttcca
     9001 atgttctctc aaaactcttt caacattttc taaatcattc tccctcataa attttactac
     9061 ttcaatatgt tgattattgc tgtatgtcaa cattttatat aactcatctt cattatcact
     9121 agtatatgac tttgacataa aattatatct taaagagttc aatagattta ctaacacctg
     9181 attatctgat ttagttatgt atatatcgtg aaattcatta cttaatttta aatagctatt
     9241 gtaattttta tactttatag agaccgccat catttctgtt aattcttcca tttttactag
     9301 gtctgattca gttaaatttt gtaatgctga agaaccggct aacgcatcca atactccaat
     9361 tacggaatag gtgtctaatt tctccttttc ctgaaattct tttactacaa atcccttatt
     9421 aggtattttt tctagtaaat tttcacctgc taacctagtt aatgcttctc tagctggtgt
     9481 tctactaact ccgatagatt tacaaatctc agattcagta attctctgat tagcttcata
     9541 ctctccattt tggattttct ttgatatata gtcatatact tgagttgtaa gtggatctac
     9601 cttcataaga cgttcctcca tattaagatt ataaaagtta aatctcccta caactttggt
     9661 agagagttca gttttatctt actaatttat ataatatcac aattatgata ttttttatac
     9721 ttctttgtaa tattttgaaa cactaaaatt cttatgataa tttatacaaa aaaagtagaa
     9781 aaagttttga taaaacaaaa ctctttctac attcacctta ttttctattt atttttctaa
     9841 aaaaagatat ttaatttact ctaaaaattc taaatgattt agagtctaaa tctactttca
     9901 actcattatt ttcaatttgt atagtactat ttgcattttt aagactatac tttataggta
     9961 tttcctcaat aaaactactc tctatacata atgatatact ttccacattt tcacttctat
    10021 ttactaaaat taacattcta tcattatttt catcaactct aataaaagaa aatacagaat
    10081 cattattagt atatataaat tctgtatttc cagaacttaa aagtttattc ttatttctaa
    10141 tttttataac atctctataa aaattaagca tatcttcgtc ttcatttttc catggataag
    10201 ttcttctatt atctgggtca acacctccac aaagacctgc ttcatctcca taatatatat
    10261 atggtactcc ttcaaatgtc atctgtatag ctacagcaag cttcactaaa tctacatcat
    10321 catttaattc cgttttagct cttgtaacat catgtgttcc aattaaattt aaattagacc
    10381 taaatgattc ttttggataa ttttctttaa tctgcatata tctattacaa agttcatatg
    10441 aattaatttc tccttttaag aaagaaaaca tgttatttct aaaaggataa cccataacag
    10501 aatctaattc ttcacctaat aaataacttc ttctctgacc atagctaatc ttatttgatg
    10561 catcttccca tacttcacct ataagaattg agtcatcatc tgcctttttt aattcctttt
    10621 ttaactctct tataaactta gttggtaatt cgtctgcaac atctagtctc cagcccttaa
    10681 tacccatatt tacccattta tttataacgc tatcattgtc atatattata taatccatat
    10741 agctatgttc taattcattt atatttggca atgtcttaac atcccaccaa cttttatact
    10801 tttgaggaaa ttcttcaaac atataccatg aataatatgg agattcttta gattgatatg
    10861 cccctaaact attatagttt ccatacatat taaaatattt actatctgct ccagtatgac
    10921 taaaaactcc atctaatact attgatatac ctttttcttt tgctttatca ataagttctt
    10981 taaatgtatc ttcatcccca aacattgggt caattttttt atagtcacct gtgtcatatt
    11041 tatgattact agaagcttca aatatagggc ttagatatag tatacttaca cctaattttt
    11101 ttaaatatcc aagtttattg attatccctc ttaaatttcc accatggaaa tcccatctta
    11161 taacatcccc ttgactatcc tttatgtaca taggtatatc ttcccaattt ccatatatga
    11221 aactattttt tttaggatta tcaaccttac cactacgatt tccattattg aatctatcta
    11281 caaatatatg ataaagtatt ccttctttgt accatgttgg tactttaaaa tctttgtaaa
    11341 cagtgatttg atatttatta atatcactat aattatattc acaagaatat ccattatctc
    11401 tgttttttcc ataaaataaa gtctttatct gaccatccat ttcaacatca actttaaagt
    11461 aataaaaata aacacctgta ccatcaaact tttcaatctt accacaaaag cactttccaa
    11521 gtttatcatt atctaattct tcatttaaag ttattgttct catttcttct tctctattta
    11581 tttctaggga aatagacttg atattgtatc cctcatttac tttaacacaa atggtcaatt
    11641 cctcatcaaa ttttaaagct ccaaacggag ccttaaaatt tttatcccaa gagttatatt
    11701 ctattacact ttgcatttaa tcacaccctt ttaaaccaaa tgtcttttgc atactcagaa
    11761 attgttctat cagaagaaaa aaatccagag ttagctatat taactaaaga cattttattc
    11821 catttttctt tatctctata taacctgttt atatctgctt gagcttgacc ataattttca
    11881 aaatctctca atacaaaata ctcatcattg taagtagtga gtgaattata aatacttctt
    11941 ccttcttcgc caagattagg aataaatcca tttattaaat catctaccac cctttttata
    12001 tccatattag aatgatataa gtcaagtgaa gaatatccac catatttatt ataatttagt
    12061 acttgttctg cactaagtcc aaataaaaac atattttctt taccaacctg ttcacatatc
    12121 tctacatttg cgccgtcaag tgtagccaaa gttatagcac cattcatcat aaacttcata
    12181 ttacttgttc cagatgcttc cttagttgta gttgaaattt gctcactaac atttgctgct
    12241 ggtattatta tttctgctaa tgatactcca taattctcta aaaatactac ttttaacttg
    12301 tcctttactc taacatcatt atttatagta cttgcaacag aatttataaa tttaattata
    12361 catttagcca aataatatcc tggtgctgct tttgcaccaa atataaaagt tcttgggtca
    12421 agattcaaat taggattatc aagtaattca tgatacatat gaagtacatt aaatatattc
    12481 agtaactgtc ttttatacgc atgcaatctc ttaacttgaa catcaaatat cgaacttggg
    12541 tctacattta aatcgtattt atcttttata aactttgcta gatttgcttt attattgtat
    12601 tttatatcat caagtctttg taaaacagag gaatcatttt taaatttttc aatatttttt
    12661 aattgtaagg tatccttctt ccatgaatca ccaattaaat ctgtaattaa attgctaagt
    12721 tgaggatttg aacttataag ccatcgccta tgtgcaattc cattagtctt attattaaat
    12781 ttatttggtt catcttgata gaaatctttt aatacctctg tttcaagaat atgagtatga
    12841 agcttagcaa ctccatttac actatgactt gtgacaatac ataagtttgc catattgata
    12901 ttgtcacagt ctattatact cattcttttt attctatcct gctcatatcc tttattattt
    12961 aattcctcta catatcttct atttatttct tctattatca tataaattct tggtaatagt
    13021 tctttcatca tacttacagg ccatttttcc attgcttctg acattatagt atgattagta
    13081 taggacactg tttttttagt tatttcccat gcttcatccc aagataaatt ttcttcatca
    13141 agcaaaattc tcataagttc tggtatgcat aaggtaggat gtgtatcatt tatatgaatt
    13201 gctaccttat cgaataaatt atcaatattt aatttgttct ttttatattt tcttattata
    13261 tcttgtatcc ctgcacttac aaaaaagtat tcttgtttca acctcaacaa cttacctgca
    13321 tagtttgaat catcaggata taatacctgt gatatttcct cagtataata cttatgtttt
    13381 aaagcctctt catagctacc agaataattt agagcatttg aggtaagttc accaaaatct
    13441 ctctttggta tttcactctt aaacaatctt aaagtattta tacattggtt ttggtatccg
    13501 attattggta tatcataagg cattgccatt acaggaaggt agtttttatg aattactttt
    13561 aaatgactac cttccttgat taattctacc tcaccaccaa acttcaccat tgttgcttca
    13621 tttggtctta cagtttccca tgcatatcgt ccttctgtaa gccagttatc aggcacttct
    13681 acctgataac catttacaaa tttttgttca aacagaccat atttatacct tattccatat
    13741 ccttgaccac ttatgttcaa agatgccata gaatctaaaa agcaagctgc taatctacca
    13801 agtccaccat ttcctaaggc tgggtctact tcagcttcaa ttaaatcatc caagttgatt
    13861 cctaattcag ataaaccttc tctaacttct tcttcaatat ttaaatttaa taaattagat
    13921 tttaactgtc tccctattaa aaattctaaa ctaaaataat aaacttcttt tttcttatct
    13981 aactttgtag caacccattt ttttgctatc tcatctttca atagactaca taatacattt
    14041 aacaattgtt catcagtagc ttccttgata gattgtgcat ataagctata catttttact
    14101 tcaaattttt gcttgaattt ctttttgctt attgttacca aaaaaaccac tcctttaatc
    14161 acatatgtct ctatatgttt ctatatactc cttagctgat tttttccaac tattatctgt
    14221 tttcattgca ttttcaacta atttaatcca tttttctttg tccttaaata ctttgattgc
    14281 atttttcaaa cagaaaaaca tctcatgagc attgtaattt ttaaaactaa atccattgcc
    14341 ttctccagta aatttattat aaggtgttac tgtatctcta agccctccag tctctctaac
    14401 tattggtaaa gaaccatatc tcatagctaa catttgacct ataccacaag gctcaaataa
    14461 tgatggcatt aagaacatat cacttgcagc atatatctgt tgagccaatg atgcattaaa
    14521 agtaattcta gctgatactt tatctgaaaa attagaatcg taatagttga acattgattg
    14581 atattgatgt tctccagttc ctaaaacgac aatctgtaaa tcttctctca taagttctgg
    14641 catcatgtat gctattaaat caaatccttt ttgagaaact aatctcgaaa ctatacctat
    14701 caacggaata gatgaatctt ttttaagtcc caatatatct tgtaatctca atttattttc
    14761 tacttttttg tcaattgagt ctacatcata atgaacaaat atatctttat cttttgcagg
    14821 gtcgtttaaa tcataatcta taccatttaa tatacctttt aattttcctg actcttttct
    14881 aagtaatcca tctaattgtt caccataaaa agatgtttgt atttcatttg cataagtagg
    14941 actaacagtt ataattttat ctgcaaaatt tataccagct ttcataaaat ttattgagcc
    15001 ataatactct atatctctat tatcaaagta tttttgtggt aagtccaata tatcatataa
    15061 aacatgctta tcaaatacac cttgatattg gagattatgt atagtataca tagtttttat
    15121 atttttatac ccctcaaggg ttgcatatct ttcttttaga attaatggta acatccctgt
    15181 atgccaatca tttatatgta ttacatctgg ataaaaatca attctactta tagcttctaa
    15241 aactgcatct gtaaagaaag tatatctttc tgcatcatct ccatatccat agatactctt
    15301 tctttcatct tctcttctaa aataaaattc attatctata aagtaaaatt ttacaccatc
    15361 caattccatt tctaaaagac cacagtattg atttctccat ccaacacgta cactaaacac
    15421 agctatttct tttagttgat cttttaaata acttggtata gttgaatatt tgggcattat
    15481 tacccttaca tctacacctt ctttttttaa ttctttaggc aatgcataag aaacatctcc
    15541 taatcctcca gtttttgcaa agggccaaca ctctgctgtt acataaaaaa ccttcattag
    15601 tcattccccc ttctaaaaaa tttatttata tatttgtatt cttttccact acaagaggat
    15661 atttttcatc tcctcttaat tctttcccat ttgatacact cgtattttta tctaatattg
    15721 cattatatag ttttgcattt gactttatta cacaattttg cattactatt gagttctcta
    15781 taactgttcc tttttcaaca tttacctttc taaatatgat actatctttt acagtacctt
    15841 ctattaaaca accagatgct ataaagctat tttctacttt agcactatct gtataaattg
    15901 taggtgattc attcttttct tttgtaaata tctttctttc agagtataat aattcatctg
    15961 caacttctaa atttaataaa tctttgctca tttcaaaata tgattcaaca gaatttacac
    16021 attttagata tcctgtatat tcataagctc ctattttcat attttctgct tcttcaataa
    16081 taaattcttc taaataacaa taactgcctt tatttacaat gttatatata cattcaacaa
    16141 aatcttcacg cttcataata tatgtctcca tacatatgtt tgctctaggg aatttgccta
    16201 aattatttcc tacatttatt accctattgt tactatctaa atttagtgtt aagttaccag
    16261 caaaatcttt atttgcatta tttacatttt tatatattat agttatatca ttatgagatt
    16321 ttttatggta ttccaatgct tgagaataat ttaaattgca tagcatatag cttggagcta
    16381 ttaaaatata ttcttcttca ctcttttcta tataatctag attagctaag atagtatata
    16441 tatcaccttc tctatgtgag taagtatttc tatacttagt gttttctgga ctaaaaattg
    16501 ataggccacc tttttttcta cttaaatccc aatctttacc actacctata tggtctgtca
    16561 atgatctgta tttttctttt gcgaatattc caactttagt gattcctgaa tttatcatat
    16621 tagataaagc aaagtctatt attctatatc ttccagctat tggtgtagat gctattggtc
    16681 ttccatagtt aagtttgttt attgctgggt ctcctttttt gtttaaattt attatcccta
    16741 aacattcatt tctcatctta aagacctcct tctattaata cgcatctagg ttcgatattt
    16801 tcatactcag aaactacatt tatttcatta tttacattct ttatctgaac attatcattt
    16861 atagttgcac actcacctat catagctttt tctatagtta cattttcacc tattacaaca
    16921 tttggcatta ttactgaatc aattacttta cttcctttac caacaacaac tccatgtgat
    16981 aatacagagt tgcctacttc acctaaaatt ctacaaccat cagctatcat tgatctatga
    17041 acatttgcat ttttacctat atattgtgga ggcattgcca tagtatttgt atatatcttc
    17101 catttagggt ctgctaaatc aagtgtttct ggagatttta ttatatccat attagcatcc
    17161 catagacttt gtatagttcc tacatctctc cagtatcctt taaatggata agcatacatt
    17221 ccaacattat cttctaacat tttaggtatt aaattttttc caaaatcatc ataatttatt
    17281 tctggatttt tttctgcttc cttaaaataa tttctcaaca ttttccaatc aaatatgtat
    17341 actcccatag atgccaaatt gctcttaggt tcacttggtt tttcttcaaa ttcatagata
    17401 cttgaatctt catttgtatt cattatccca aatcttgaag cttcatccca aggaacttca
    17461 atcactgcta ttgtagcttt agagcgtttt tccttatgaa attttaacat tttgctataa
    17521 tccatcttgt atatatggtc accagataat atcaatacat attctggatt ataggtatct
    17581 acaaagtcca tattttgata tatcgcatgt gctgtaccat tataccaatt tccttctttt
    17641 tcattcataa atggttgtaa aacatagaca ccaccattta ttctgtccaa atcccaatga
    17701 cttcccatgc ctatatgtga atttaatatc aacggtctat attgagttaa aacacctaca
    17761 gtatcaatac cagagtttga acaattactt aacacaaaat ctataattct atacttacct
    17821 ccaaatgata cagctggttt ggcaattctt tttgtaaaaa cacctaatct tgaaccttgc
    17881 cctcctgcca aaatcatagc taacatctct tttttcattt aatgacactc ccctcatcta
    17941 gtaattaata tttataattg catttttact tttataaact ttatcagtca ataaatgccg
    18001 tgtataaatg ttgcttaaat aataccttaa taaaaataaa ataatatcaa ctatacaatt
    18061 gatataatgt ataccccata atgaacttac cgacgtatac attattttcc ataagcacta
    18121 tagtatttat taatattcaa ttatcggtta aaaaataata caaattttat tttataaata
    18181 taaaaacatt ttttataaat cccttgtgtc atataaacat gcttattttt taatttgtta
    18241 aattcgtaat agcaaaatat aatctaatat ttgttaaata attatccaaa gaaaatcaag
    18301 taattattaa tcaactttat tttttaattg atacttcttt gtctataatt taaacaaaag
    18361 gatataaact tttaaattat ttattagttt tcttagtatt aatgtttata tttttataaa
    18421 tatatattaa taatataaat agactaacta aaaccatgct tatttgctat atgttttata
    18481 taatattata taacactttt tacattagta aaggataaat tgtataaaga ttctgttaat
    18541 tcatttttat aatttcatct ttctaataaa aacaaagaag aagacttaaa aatttataag
    18601 tcctcttctt ttcaacgtgc atttttgtgc tatatttaat taattcgacc tttaatttcc
    18661 atatccttcc tatgataaca aaactctttt atttttttaa tgattcatta tcatttaaaa
    18721 cttcttttat atcaagtact tctttgttat catcactcat aacttccttt attcctttga
    18781 atgttcctag gaaattaact gcttctgaag gtaaaaccag ttttgttgac ttaccttcag
    18841 ccattttttc aagagcttcc atagatttta atgctagaat attattgtct atatcagcct
    18901 ctttcattgc tgaaaaaact aattttaaac cttctgctgt tgccatttga gttcttttta
    18961 tcatttcagc ctcaccttgt gccttagcaa tagcggtctg tcttatagct tcagcttcac
    19021 cttctgccac taatatagca gattcttttt caccttctgc tacacgtacc atagcttctt
    19081 ttttggcttc tgctgttaat atcgcagatt gtttttcacc ttctgcttga agtattgcag
    19141 ctgacttatt accttctgct tgaagtattg cctctcttct ttctctttct gctctcattt
    19201 gtttttccat cgcaacttga atatcctgag gaggcattat attttttaac tctactctat
    19261 ttacttttat accccattta tctgttgctt catcaaggat agttctcatt tttacattta
    19321 ttatatctct tgatgttaat gtttcatcta aatcaagttc accaattata tttcttagtg
    19381 ttgtagctgt taaattttca atagcagcta ttggattagc tatctcaaac acatatctaa
    19441 ctggatctgt aactttataa tatacaactg tatcaatctg catagttaca ttatctttag
    19501 ttataactgg ttgaggtgga aaatctatta caatttctct aaggtcaatt acatatgcca
    19561 ttttatctaa aaatggtatt aagaaatgta cacctgtttc agccactttt tgaaacttac
    19621 caagtctcat tattatacct actttagatt gttttataac tcttatacac gttaaactta
    19681 ttgctacgac tactactatt aatacaatac ttaaaacaat tttagtaccc atactataaa
    19741 tcctccttta ttctattggt ttgtcacatt aactgtggcg tctacttttt taacaactaa
    19801 ttttacccct tcaattttta atacttctac tgtagaacct ttttctatct tttcaccatc
    19861 tatagaaata gccgtccatg tttcatgttc aactacaact agacctgtgt tatttggaga
    19921 aatctcttct gtaacaatac cttttttaga catcattgct tgtaaattag tgttagattt
    19981 atagccttta tcttttttta ctattttttt agtagctacg actaacattg ctatagaaat
    20041 tactgcaaat attaaaattt gtaagaaaat actctctata aagctactta aaaatataag
    20101 tattacagct cctacactaa accatatcaa tgttaagctt ggtgttaaca tttctgctat
    20161 tccaaataag actgctacta tcaaccatat taacttcata ctatctaccc tcttttcata
    20221 tgaattataa aaccctatat aaattatatg tttatacaat gtttttgaat ataaatttaa
    20281 actacaaatc aatagaataa actaatctaa gattaattta atagtattat atcaacatac
    20341 tttgttaaaa ttgttacaaa gta
//
LOCUS       DAEQJM010000062        19943 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.062, whole genome shotgun sequence.
ACCESSION   DAEQJM010000062 DAEQJM010000000
VERSION     DAEQJM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19943
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.062"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            28..726
                     /locus_tag="KRQ43_002862"
     CDS             28..726
                     /locus_tag="KRQ43_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743207.1"
                     /translation="MKISSQYRSQYSFRHESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINEAIKNLYKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            828..1376
                     /locus_tag="KRQ43_002863"
     CDS             828..1376
                     /locus_tag="KRQ43_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743208.1"
                     /translation="MEGLGFYAAALSGSSYQRIGFGKLDPIEVIADGDWISYKQAQDT
                     LTVIRNFLNSFDWRNASEMERANRAAKLVTEAKYVDSKYCNIVYGNLVDKRGVCGSFA
                     SSFHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRSDGSEISAFGGALDFDYRKLK
                     DATREMTTYYDAKALSILGFNQ"
     gene            complement(1777..2733)
                     /locus_tag="KRQ43_002864"
     CDS             complement(1777..2733)
                     /locus_tag="KRQ43_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH2743209.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDNNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSYGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIQFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENKSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            3436..4431
                     /locus_tag="KRQ43_002865"
     CDS             3436..4431
                     /locus_tag="KRQ43_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2743210.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKTSVIVLKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            4409..5272
                     /locus_tag="KRQ43_002866"
     CDS             4409..5272
                     /locus_tag="KRQ43_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH2743211.1"
                     /translation="MSIMSNYNEASSNYSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            5269..6063
                     /locus_tag="KRQ43_002867"
     CDS             5269..6063
                     /locus_tag="KRQ43_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH2743212.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISKLNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            6348..7727
                     /locus_tag="KRQ43_002868"
     CDS             6348..7727
                     /locus_tag="KRQ43_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2743213.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKELLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            8182..8895
                     /locus_tag="KRQ43_002869"
     CDS             8182..8895
                     /locus_tag="KRQ43_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743214.1"
                     /translation="MDTYFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSAVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(9167..10705)
                     /locus_tag="KRQ43_002870"
     CDS             complement(9167..10705)
                     /locus_tag="KRQ43_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH2743215.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVEEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            11588..12043
                     /locus_tag="KRQ43_002871"
     CDS             11588..12043
                     /locus_tag="KRQ43_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH2743216.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            12092..12676
                     /locus_tag="KRQ43_002872"
     CDS             12092..12676
                     /locus_tag="KRQ43_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBH2743217.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSREQMDEVKLAMGFKL"
     gene            complement(12681..13004)
                     /locus_tag="KRQ43_002873"
     CDS             complement(12681..13004)
                     /locus_tag="KRQ43_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743218.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLESL"
     gene            13156..13674
                     /locus_tag="KRQ43_002874"
     CDS             13156..13674
                     /locus_tag="KRQ43_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH2743219.1"
                     /translation="MNFVELTKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGRQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(13850..14518)
                     /locus_tag="KRQ43_002875"
     CDS             complement(13850..14518)
                     /locus_tag="KRQ43_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743220.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            14633..16048
                     /locus_tag="KRQ43_002876"
     CDS             14633..16048
                     /locus_tag="KRQ43_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH2743221.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNSKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQYVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            16271..16729
                     /locus_tag="KRQ43_002877"
     CDS             16271..16729
                     /locus_tag="KRQ43_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743222.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            16726..17310
                     /gene="clpP"
                     /locus_tag="KRQ43_002878"
     CDS             16726..17310
                     /gene="clpP"
                     /locus_tag="KRQ43_002878"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH2743223.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            17632..18708
                     /locus_tag="KRQ43_002879"
     CDS             17632..18708
                     /locus_tag="KRQ43_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH2743224.1"
                     /translation="MIAISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            18775..>19943
                     /gene="bclA3"
                     /locus_tag="KRQ43_002880"
     CDS             18775..>19943
                     /gene="bclA3"
                     /locus_tag="KRQ43_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HBH2743225.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGGTGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGGTGPTGATGAIGFGVTGPTGPTGPTGATGATGADGVTGPTGPTGATGADGI
                     TGPTGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGI
                     GITGPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGATGA
                     TGIGITGATGLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGVTGADGATGATG
                     ATGATGPTGADGLVGPTGATGATGADGLVGPTGPTGATGVGITGATGATGATGPTG"
BASE COUNT         7396 a         2381 c         3272 g         6894 t
ORIGIN      
        1 taaatttatt ttagagaggt gaaataaatg aaaatatcta gtcaatatag aagtcaatat
       61 tcatttagac atgaaagtaa tataaataat acaagaataa atgaaagtat ggttaagaaa
      121 aatgaaactg taggaaaaga cacttattta tctaatatta tgaaacaaaa gcaagaactt
      181 aatgatagaa ttagagattt aaaatataga caagaggttt atactaaaaa aataaatgaa
      241 gcaattaaga acttatataa atcagaaata agagaaacaa ctaataactt ttctaatata
      301 gaaataggta ttaaaaatag cattatagaa gataaaaata aaagtacaat gttagatgaa
      361 aattcaactt atctaaatac aaatgatgaa aaagaatctt taatcactaa agagtctaat
      421 gaaaaaattg aagaagaaat attaaatgat gaaaaattag aagagttaga acaaaaaaag
      481 gattataaag aggattctaa taaaaaagag aaagtatctg aggacttatc tttagtaggt
      541 aaaactcgtg aagagcttga aaatatgctt aaaaatttta taaatttaac acaagaagaa
      601 ataatgaaac ttgagtcgag aatagaaaag ttagataaag atgctgaaga atacaaacaa
      661 aattcaaaga ctaatatatt tgataaaaca gatgaacaaa aaaaacatat aaatgtactg
      721 atttaaacaa tatgttttaa aaaaataagt ttaatttact ctatggagga aatccaaatg
      781 gagttgagct tcgagcagat ggtaaatatt attatataaa taagggtatg gaagggctag
      841 gattttatgc agcagcattg tcaggtagct catatcagag aataggcttt ggaaaacttg
      901 accctataga agtaatagcc gatggagatt ggatttctta caaacaagct caagatacac
      961 ttacagtaat caggaatttt ttaaatagtt ttgactggag aaatgcatct gagatggaaa
     1021 gagctaatag agctgcaaaa ttggtaaccg aagcaaaata tgtagactct aaatattgta
     1081 acatagtcta tggtaatctg gttgataaac gtggtgtatg tggaagtttt gcaagtagct
     1141 ttcatttatt aacaaggtta atgggaatgg attcactatc tatattaaat ccatcattaa
     1201 atcatgcttg gaactatata caaattgatg ggaaatggta taggtctgat gggtctgaaa
     1261 tatcagcttt tggtggagca ttagactttg attaccgtaa attaaaggat gcaacaagag
     1321 agatgactac ttactatgat gctaaggcat tgtctatatt aggatttaat caataaaaat
     1381 aggggaggct ttataaagag ccttttttta ttgatttgaa atttaataag gaattttata
     1441 tgaaaattta atcaataaaa gcaaaaaagg ctctttataa agcctttcta agtgtttttt
     1501 taagtaaaat tttttatatc aacatcagtt ttaatcaaaa aatataacat tttggactta
     1561 cttttaaaaa taaaattatt aaaatataat attaatcatg ttaataatgt ttttagttta
     1621 ttatattcta taatagtggt catgttgact attgtagttt tattaagaat agttggttta
     1681 tataaatata tgcaaagata gcttgttgtt tactttactt attagtatat aggacaagat
     1741 actctaataa atttgcctat tttaatatct tttgtactaa aaccaactaa agtttccttt
     1801 attatttcgt tttgaataat acaaagcata atccgattgt ttgtataaag actggaaagt
     1861 atcagattta ttttctaatt tagatatacc tatagaacaa gaattactct ctagacataa
     1921 ttctaaaact ttctttgctt tattttcaac attctctttt gattgattac tatattcaaa
     1981 aacagcaaat tcatctccac caagtcttcc aataatagca tcatttacga atactttagt
     2041 caaaatattt gaaaactgta ttagtatttc atctcctcga acatgaccaa agatatcatt
     2101 tacctgttta aaattatcta aatcaaagat gtaaaagtat ccatatgaaa cagttttaag
     2161 catttctttt atgtgtactt caaaaaaatg tctattgtat agtccagtca taaggtcttt
     2221 ttctgatttt agtttaaatt catttgccat tgctagtgct tcttgtgctt tttcagttat
     2281 tgttttaggg taatactcat ctttcatttg gtcaaagttt ggaatagaat ggtgaacatg
     2341 gataagttta atcatatcat ctgtaactct gtataccata gtaaatcgag tatccatttc
     2401 tacatagata tctttttcta ggtaatcttt ttctattacc caaagagtac catatactat
     2461 aaaagcttcg tctgtaactt tggtacatga ataccactca tctataatct caaagtctat
     2521 ttgctctgat tctgtttggt ctttttcaag acctataata aattcttcta atgtttcgta
     2581 aaattcatgt tttcctgttc caattaatgc aaggttgtta tctaataagg aaataataaa
     2641 tttaaggttt tcttcttctg gatttaaaat ataaatatgc caaatttttt ttgataaatc
     2701 tcttaattgt ttttgtattg tattattttc catagattac ccccttaaga tttacagttt
     2761 atattttact gtattataag ttgaactctt attacaatat tattataata tagaactaaa
     2821 gaaattacat cctgtatagg taaaagtata tcttttacaa taaaaatatt acagtaaaat
     2881 aaccagtttt aatatacgta ttatattttt aatttataaa cgaatattat aaatgaaatt
     2941 taaattcaac cctgaagaaa taagctaaat gtattagtat ataaatccat acttgaacat
     3001 aaataacctt tatgatatga tatcaataat aatattatga gaggagtgcc ttgatgtcgg
     3061 agttatataa tggtaaccaa caattaaata gttggagaca catatattct gtataatcag
     3121 aaattttaag tgtattttta atacatttaa tttttgtgtc ttattctgcc tttatagata
     3181 actgacatat gacaacaaat agtatttaaa atatatatta ctttgttaaa ttatggtgta
     3241 gtaggcttta atctgctaca cttttattaa ttttgtatag tattattttg ataactattt
     3301 tgaaatagag agcattaatt tttctagtcc acaggagttt tctgtttttg tgctgttaaa
     3361 tataagcaca gaaaaaggca gatatatacc tgtggacttt ttttatataa attatgaaat
     3421 atggaggtag ttaaaatgag tataattgaa cttaatgaac tgactaaatc ttatagaaga
     3481 tttgagaaaa aggcaggatt tatggggagt gtaaagtctt tatttaatag gaaatataca
     3541 gaaaaaacag ctatatcgtc atttgattta aagatagaag aaggagaatt tgttggatta
     3601 ataggtcaaa atggagctgg caaaactact cttattaaga tgttaactgg tattattgca
     3661 ccgtcttctg gagaaatatc tgttatgggt tattacccta acaaattaga aaataatttt
     3721 aaaaaacaat atgctgttgt tatgggccaa aaaagtcaac tattctttga attgacacca
     3781 gcagatacgt ttcttttatt taaagaatta tatgatatat ctaatgaaga atataaaaaa
     3841 aacttggatt actttatcga attatttgag gtatctgact atttaaatgt tcaagttagg
     3901 acgctttctt taggagaaag aatgaaaatg gaattaatag tagcccttct acataatcca
     3961 aaaatattat ttttggatga accaactata ggcttagatg ctatagccca aaaacaaatt
     4021 aggtatttcc taaaagaagt aaatgaaaca aaaggaacta ctattatact tacttctcat
     4081 tacatggaag atattaagag tctctgtagt agaagtattg ttgtagaaaa tagccgtaaa
     4141 atatatgatg gttctacaga gaaactattt aatcattttc aaaaatataa aaaaataaca
     4201 gttagttttt ccaatgaaac taacattgta tttccaaaag attgtaaagt tgttgaacaa
     4261 acaaatcata agacatcagt aattgtgcta aaagaaagag gaaatgaaac gattaaatgg
     4321 atttttgata aatatgatgt taaagatgta atgattgaag aagaagatat aggtagtatt
     4381 gtagagagaa tatataagaa aggaagtgat gagtattatg agcaactata atgaagcaag
     4441 ttcaaattat tcaatgtttt ataaatttaa acaaagtatt agaaggtatt atgaagtagc
     4501 caaaattaac tttaaagtgc aacttatctg gagatttgat gtggtggtta atatggtgtt
     4561 tacgattgta aaaattttat ttgcttatat tttatggaaa gcaatttttg gtgaaaataa
     4621 aatagtctct ggttttacat ttaactctat gttgtcttac tatataataa gctcattttt
     4681 agcaggtatt gatatgtcaa agagtaccag tgaagagata tgtaatcgtg taaaattggg
     4741 cacattttca aagtacatga ttattccaat taatgttcaa aattatttta ttgctaaaaa
     4801 ttttggaatg acatgttttt attttgtatt taatatgatt tctgcatttg tatggatttt
     4861 tatatttaaa atagattttg cctttacatc aaatccagtt caaatattaa tttcaatttt
     4921 gatgattttt ctagggttta tttttatgat gaaactccac ttctttattg ggattttgtc
     4981 atttaaattt cttgagatta gtttttttag aatgataatt gaaaatattg ttgaatttat
     5041 tacaggaaca atgataccac ttgtactctt accagaaact atagtaacag ttatgaaggt
     5101 atttccattt tattatacaa catatttgcc atctatgtta ctaataggta gaaacagcaa
     5161 tgaggcaata caaggattaa ttattctagc attatgggtt ttattttttt ctgtagtaaa
     5221 taaagttatg tataaaagaa tgagaacatt atttgatggg gtgggtatat gatgaaaaaa
     5281 aatttgaaaa taatatttat gttattaaaa atgaaattat caaagatgat ggtatttaga
     5341 tttgattttt ttggagcatt ttttgtagat agttcattat ttatattaca acttctaatg
     5401 tttaatagta tatattctca tgtagactca atagggggat ggcaacaagg agagatgtta
     5461 atatttatag gaactttctc attaataaat gcgataaata tgacgatttt cttttttggt
     5521 atttatgata ttccacgaaa aatccaagaa ggagaattag actactatat tacaaaacca
     5581 ttagacccac tatttaggtt aacatttgaa aatattaata ttggttcatc accattaatt
     5641 ctagcaagta tacttattgt tttatatgga atatctaagt taaactcaga gataacttta
     5701 gttatgataa taatatatat tttcatggtg ttattgatga cattactttt ttatgatgta
     5761 tgtatcatac ttagaacagt ttcatttttt gttatatcat cttctgcgat aatgagatta
     5821 gaagataatt tattgccaat gaatatgaaa attcctggtg taatatatga aggtgttttt
     5881 aaagtattat tctatttaat cttaccatat ggaattatgt cgacaattcc gactcaaatt
     5941 ttggctggga caataacaat taatggatta atatactcaa ttttaattgt atttttgttt
     6001 acattgttta tgtggagatt ttggaagtta ggtatgagac attataaaag tgcaagtagt
     6061 taataaatta gtaaaaatag acaatgtata actatatata aatacgtttc atatgacact
     6121 aaactatgtg aacaagtatt tgcgctaaag gcactgaaag ctataaaatg attaaagtaa
     6181 ggatttaaaa gtttctttag tagaaatata attgtgtaaa aaagcaagat taattaaaac
     6241 tatatccaaa taattagata taattcttat gcagaaagga ggtctgtaaa tgtctaattg
     6301 tttggaatat attttaaaaa taattaatgt acagaaaaat aaacaaaatg agtgatgtat
     6361 attattcaga aaatcatgaa caagataatc tttatgagca agataattta ctggcacaaa
     6421 gatttaattt atttactcta ttgaagtttg catttcctac tatttttatg atgattttta
     6481 tggggttgta tacaatcgta gatactatat ttgtatcaag atttattaat acaaatgctc
     6541 tatcagcaat taatattgta tgtccaatta ttaatcttat agttggaatt ggaactatgc
     6601 ttgccactgg aggaagtgct attgtagcac gtaagatggg aaatggtgat attgagggag
     6661 caaataaagc tttttcttta atcgtattat caggagttgt aattggggta ataattactg
     6721 gtataggtat tgtatttatg gattatatca ttatatggtt aggagcaagt gaagttttaa
     6781 ttaaatattg tcgttcatat ctttttatta tcttggtttt tgcttctgca aatatactac
     6841 aagtattatt tcaatgttta tttgtaacag ctggaaagcc tcaatttgga ttatggctag
     6901 tgttaggtgc tgggtgtgct aatataattc ttgactatgt gttcattgtt ctgttacaaa
     6961 tgggtattag tggagcagca cttgcaactg gagtaggata cctaattcct accgtttcag
     7021 gtatggtttt cttttcaaaa aataaagagt tacttaagtt ttgtataccc agactagata
     7081 aaagaatatt atttgaagct tgttttaatg gttcatctga aatggtaggt caactatcaa
     7141 cagcagttac tactttttta tttaatgcta tgatgatgaa attaattggt gaggatggag
     7201 ttgcagctat tacaataatt atttattctc aatttctttt aacttcgctt tatataggtt
     7261 tctcaatggg tgttgcacca ataataagtt ataactatgg aagtgaaaat aatacacagt
     7321 taaatcatgt ttttaagatt tgtatattat ttatttcagt ggcatcttta ttggtattta
     7381 tcttttctat atcatgttca ccaatcattg tagagatttt ttctcaaaga ggaagccgag
     7441 tttatgaaat tgcaaggtct ggattttata tattttcttt tagttttatt ttttgtgggt
     7501 ataatatttt tacttcgtct atgtttacag cattgtcaaa tggcaaggtc tctgcaatat
     7561 tatcttttct acgtacattt ggatttataa ctataggttt attgatactg ccaaatatat
     7621 taaatataaa tgggatatgg ttagcagtac caagtgctga gattttaact ttatttttaa
     7681 ccattttttg tatatgtaag tataagaata gatataaata tatgtagata ttaaataaat
     7741 agtttaggta gatattttat gttttaataa gtaattcaat tagtggtaga tatatactat
     7801 tgaaaattaa agttataatt gatataaaga attaataaaa ataacatata aaagtttaaa
     7861 agggagttga acttaaagtt tgattagaaa aagtcaattt taagacaact ccttttattt
     7921 tactattgta ttaatctgta tctgtatctg taagtgtatt agtctaatat tataaacttt
     7981 ggatgaaatt aattttctat aggttttaat gtatcataca ctttatttta aagaaactta
     8041 tcttaatttt catagtgatt gaatttgtct attagagatg ttactattag taatgtaaaa
     8101 gcaagagtag tgaatataaa aaaacaagat attgatactg caagattaga atataataaa
     8161 tttttatgga gagatttcaa tatggataca tattttaata aaaaaatatt acttgttgat
     8221 gatgaaaaag atatagtaga tttaattgaa gaagtactca taaatgatgg ttttaaaaac
     8281 attattaaag cttataatgg tttagatgct atttcgctgt gtaagatagc atgtccagat
     8341 gttgtcattc ttgatataat gttaccagat atagatggta tagaagtgtg taaaaaaatt
     8401 cgagagtttt catactgttc tattcttttt ttatcatcaa aaaatgatga tattgacaaa
     8461 atactaggtc ttagtagtgg gggagatgac tatataacaa agccattcag tccaagagaa
     8521 attgcttttc gagttaaagc gcaattacgt agacaacagt atcaaagcat tgtaccatca
     8581 gatagtgcag ttattaaaat aggagatatt actattgata tagaaggaaa ccgtgtatat
     8641 aaagatagaa atgagattga gttaactgga agggagtatc atcttttaag ctacatggct
     8701 caaaatgtaa ataaaattat aggaaaagaa agactctatg aacaagtatg gggagtatat
     8761 agtagtattt gtgacaatac aattatggtg catatacgac atataagaga aaaaattgaa
     8821 gataacccct caaatcctaa aatacttata acggttaaag gactaggata taaacttgtg
     8881 aatagaatcg attagaatag attttaatat taatgaagat gtctcaagtt gaatttttag
     8941 ttaatgaggc attcttttat gtgtgaagtc aaatgtattt tcgttatctc aacaatgaag
     9001 aagaggtcta tctctatttt gagatagcct cattaagttt atatcctggt aatgtacttt
     9061 atgttctaat aaaatttttt tagtttattt gcagtgaaac attaactaga acattaaaat
     9121 ttgcattgaa atatcaatta aataatattg tatattgtgt ataaacttat actaattgtt
     9181 tttctatatt aaacacttta tcaatccaac ctttataaaa tttttcttca tgggaaacta
     9241 ggattatact tcctctaaac tgtttcaaag cattttgtaa agcatccttt gtctctgcat
     9301 caaagtgatt ggttggttca tccagaataa gaaaattaca aggagataac atcatacaac
     9361 ataatttaac cttagattgt tcaccaccac ttaaagtaga tacactcctt gaaacatgct
     9421 cttccttcac accacatctg gctagatgac gtctaatctc ttttgtattt aattttggat
     9481 atttatctgc tactatttga agtggggttt tatcaggatt ttcccatttt aaatcttgct
     9541 cataataacc aattttaact tgttctgaaa actggaaatc tccagatata cgaggaatat
     9601 ctttgactaa tgtctttaac aaggtagatt taccgattcc attaaaacca gttataacta
     9661 ttttttgacc tccatcaaca gaaaaattta attttggaag taaagaatag tagtatccaa
     9721 cttcaagatt tgttatagta agagcatttt gagccgatat ttcaatttct gaaaattgaa
     9781 tatttggttt tcctgtaaaa ctaggaggag ctattctttc tattttatcc aattgttttt
     9841 gtcttcctct tgcaattttt gaatttactc cagctttatt tttacgtata aatgtctctt
     9901 ctttttctat tttcttttgt tgtgcttgat accttctaat ataatcttct cttaaatgtg
     9961 atttttgttt aaggaactct gaatattttc catgatattt tttaatcata ccaaattcta
    10021 tatcaagaat acctgtagaa attttttcta aaaaatcaaa atcgtgggaa actacaataa
    10081 atgccccatt aaatgtattt aaataatttg agagccattc aacatgttct ttatctaaaa
    10141 agtttgttgg ttcatctaat aatagaacat catggttaga aagtagcaat tttgctaaaa
    10201 ttacctttgc cctttgccca ccactaagct cttcaacaac acgattcatt cctattgaat
    10261 ctaatccaag accatttgct attttattta tttcattatc tatagaatag aaattacttg
    10321 ctattagttg ttcctgataa tctgatgctt tgattagata ttgctcattt tcagatatag
    10381 cacttttttg atagagtaaa ttcatttcct tttctatttt ataaagttct tcaaatgcag
    10441 tgtgtaaata gagtgatatt gttgtatctc tattgatttc tgcatattgg tctaaatggc
    10501 ctatattgat attaggttgc cacttgattt ctcctgaatc tggaacaact tctcccaata
    10561 aaattttaat taatgtactt ttacctgtac cattttggcc aactacacct atatgttcac
    10621 ctttgaataa atcaaagtta gctttctcat acagtgattt atccataaaa cattgtgata
    10681 aattagttac ttttaataaa ctcataattc aaactccttt tcttttatta aaaaatttat
    10741 ggaaataaaa aaagcagagg aatggcattg taaaatgccg acctctgctt ttggaaaaac
    10801 aaaaggtcat agacaagcat tgttgtctat gaccagaaaa tctatactat ctatcggcaa
    10861 ataggtaatt ttaaataagc atagccaaaa aactatacta aacctatatt tgccgatgaa
    10921 gatagaaagc tttaagcttt cagattaacc tctacacaac gcttcatcgt atacatttgt
    10981 gtagagttaa gttttctaac aagtttaact aattctatat aaatcataat tattcacatc
    11041 ctaattttag tattaattct agtttatcta tatttaaatt gtacttttgt actttgtgga
    11101 ttatcttatt tatttaaaat atgttttatt aattatagct taagttatgt tatcataata
    11161 cttggttata gtcaataaga aagttatatt tgctatatat tatattaatt tagtaaatct
    11221 atcattacaa agttatttga agactcgcta ccaataaaat tttatagtct atgggaaaat
    11281 taagattatg agttttatac ttttgatata gggatactat tttcataaat attacaacat
    11341 gtagaagtat atgtctagta ttgttgaatt ttcaatgata tattaaggtt ctaatatatt
    11401 atacaaaata aaaacattaa ttcaacttaa ataattttaa gtattatatg tgttttgatt
    11461 aaagaaaact aaaattttaa ggaaaaataa catatttgta ttaaatttta ttgaaatgat
    11521 taaatttatt tacttaatgt aaattattag ctaaaattgt attaaataat taaggaggtg
    11581 agtagctctg gatgaaatag atttaaaaat aattaattct ctaaaaaaga atagtagggc
    11641 ttcaacctct gaaataagca gacaaattaa tttatcagta ccagcagtct cagagcgtat
    11701 aaggaaaatt gagcagtcaa atttaattca aaagtacact attcaaatta atcgggaaaa
    11761 aacaaaatat aagcttttgg cttttatatt tatcaatact gatttatcta aaagtatgaa
    11821 agaatttaag aaaactatat tggaatatga tactgtatta gaatgtcatc atatttcagg
    11881 agagtatgat tacttaataa aagtattagc agaagataca agtaatcttg aagagtttat
    11941 atcagtgact ttgaaggaaa ttggggggat tcaaaaagct aatacaacca ttgttttatc
    12001 tacaattaaa gaagaattta atacaataaa agatattttt taaataattt actagtaaag
    12061 tgttaattat attttaggag gaaaatagaa tatgaaagtt ttagtttttt tagcaaaagg
    12121 ttttgaaact atggaattta gtgtatttgt agatgttatg ggatgggctc gtaacgatta
    12181 tgggcatgat attgatgtag tgacttgtgg atttaaaaaa caagttatga gtacatttaa
    12241 tatacaagta ttagttgata agacgataga agaagtatgt gttgatgatt atgatgccct
    12301 agctattcct ggaggatttg aagaatttgg attttatgat gaagcatatg attcatcttt
    12361 tttaaatcta ataagggagt ttaattcaaa agaaaaaata atcgcttcta tttgtgtggc
    12421 agcattgcca gttggaaaaa gtggtgtttt aaaaaatcgt aaagctacta catatcattt
    12481 gaaaaatggt aaaagacaaa gacagttaag tgagtttgat gtaaatgtag ttaatgaacc
    12541 aattgttgta gataaaaata ttataacctc atattgtcca gaaacagctc cacatgtagc
    12601 ttttaagctt ttagaaatgt tgacatctag agaacaaatg gatgaagtta aattagcaat
    12661 gggatttaaa ctgtaatgct ctatagactt tctaagtaat cagaacccca gtcacacatg
    12721 gaatctaaaa ttggaataat actctttcca aaatcagata gcgagtattc tacttttgga
    12781 ggaacaacag gataaaccac tcttataatt aaaccatctg attctaattc acgtaattgt
    12841 tgagttaaca tcttaggcgt tgctttagga attaattttt ttaattcatt aaacctcaat
    12901 atagtgtctt taagatgcca aagtataagt gtcttatatt taccaccaat caatgcaagt
    12961 gttgcttcta ttgggcaact gtaattatct aaacattttt tcatttttga gctcctttat
    13021 ttattttaaa gtatcttttt agatactata ttacaaaaaa gtgcattatt gtaatatagt
    13081 accatagtga taaaattata gcataggtta aataaatcat caacttagcc taataaaaca
    13141 atagggggta aataaatgaa tttcgttgaa cttacaaaaa aaagatattc ttgccgtaat
    13201 tatcaagata gaaaggttga aaaagaaaaa cttgagaagg ttttagatgt tgcaagaata
    13261 gctccaactg gtggtaatcg tcaacctcaa agattgattg ttattcagga aaaagaaggt
    13321 ataaataaac tttctaaggc tgccaatata tatgatgctc cattagcaat tcttgtatgt
    13381 ggagataaag acaaagtttg gacaagacct tttgatggga gacaacttac agatattgac
    13441 acaagtatag ttacagacca tatgatgtta caggcaactg aacttggatt ggcaagtgtt
    13501 tgggtgtgct attttaatcc agatataatt agagaagagt ttagtttgcc agataatcta
    13561 gaaccaataa atatattatt gatgggatat gaatctaaga taccagagag cccagagaga
    13621 catgaaaaaa ctcgtgttcc tttaagtgaa attgtttctt atgaaactct ttaattataa
    13681 aattaagtta ttcataggat aaatgtaata aagtgtttat tataaacaaa attcaaaata
    13741 aataatatct acatataatt aattttagtg aagtatatct agtttaacta gaatgtatac
    13801 ttcactaatt tatttattca aaatatttat gaggatttta atatattaac taaaatatat
    13861 caattgaatt aacttttaaa tctggaaaag cacttgaaat atagtgtttt atgtcattta
    13921 aatggtcttg aatttgcttt tctgatattt tatcaggtcc atatacaaaa tacataatat
    13981 ttttagtatc ttttgttata gctgttcgat tatcagggcc attaagaata ctagataata
    14041 taccaatatt atctgataaa aataaatcat cttttgttaa aatatgctct ttaccaccta
    14101 taccataaaa atgttcactt ccatttgcta attctatttt caaaggtaat tccattttat
    14161 caaggtcatg acctgctgtt agaagaagat ttttcaattc tgctaaaaac attgactcaa
    14221 ttgttacacc tacatctggg ataccttttg attttaatag aatagattct aattgaagca
    14281 atacagggta agttttcttg aattttttat aatactttat ataacttgaa acaggctctg
    14341 ttttaatttt ttctttacga ttgtattctg ggtgttgttc tataatattt ttaattgtag
    14401 agtttttaag aactaaaaaa ttttctttat taggttttga atgtgtaata tttataacca
    14461 taactccaaa tttaatattg ggataaattt ctttaacttt atgtgatatt tctaacataa
    14521 tatagactcc tttttatttt atattttatg atataatctt agcaagttaa aagtggattt
    14581 tgtagttcca tttttatagt aattttatag aaccactttt ggaggtatta gaatgtggat
    14641 tacgattaat agaaatagta atatatcatt atcaagacaa atttattgtg agataaaaga
    14701 tatgattctg gatggaagct taaagtttga gcaaaaactg ccatcatcta ggactttatc
    14761 aaaagaacta tctgtatctc gtaatacagt tttagatgca tataatcaat taattgcaga
    14821 aggatatttg gaaacaagga atggatatgg aacaattgta gctaaaggaa tatcagggca
    14881 taaagttgat tttaagttaa atgatacttt tagagatgaa aaagatttac atactaataa
    14941 acaaaaaaat tatatagatt ttcgttcagg agttccagaa ttaaaactat ttccacgcaa
    15001 agaactttca aagctatata aacaaatact gtatgattta tcagattcgg atttcagata
    15061 tggaagtaca gctggtgtat gggttttaag agtggaaata tctaagtatt tatttcgtac
    15121 tagaggaatt agatgtaatt ccaaaaacat tatgattgtt tctggttcaa cacaaggttt
    15181 atctttaatt tcacagcttt tatacaaaag taataaaaag gttgctgtag aagaccctat
    15241 tcataaaggc ttattaaagg ttatttcatc tattggatat tcagttgttg gaattaaagt
    15301 agatgataag ggaatgaata ccaacttaat aaaatcaata aaggggattt cttttgttta
    15361 tactacacct tctcatcaat atccattagg agggatttta cctattcaaa gaagactaga
    15421 gcttattaaa tgtgcaacag agaatgatta ctatataatt gaagatgatt atgatagtga
    15481 atttagatat gagggtcaac caattagttc tctttatgaa cttagcccaa ataaagtaat
    15541 ttacataggt tcttttagta aaatattatc tccagctatt cgtgttggat ttatgttatt
    15601 accagacaat attttagaaa gctataaaac cttaaaaatg tactctgatg ttcatacaga
    15661 aacaatattg caatatgtat tagctgaatt tattggaaat ggaggtttag agaagtacat
    15721 atttagaatg aagaagttgt acaatagaaa acgtaaatat ctcataaaag ttttaaacac
    15781 ggaatttaaa aatgaattta aaataaaagg tgaagcagca gggcttcata tagttgctca
    15841 tttctataat gttaaattta cggaaagttt aattcataaa atttttgaag caggtataaa
    15901 agtttatcct atacaacaat atgcaattga gaatatatta gaatatgacc atgaaattat
    15961 actaggttat gctcatctta gttttgatga aattgaaaaa ggtgtaaaaa tactcagcaa
    16021 aataatacat atgaatcaag gtacatagat aaaacatgta gcaatctaca tataatagat
    16081 gtaattaagt ttaaacttta aaagaaatat atattaatat ttttgtataa aaatacttga
    16141 tattgtttta tcgatacttt attgctatac actaaattaa gatagcaatt tatattaaga
    16201 aaaaactttt tgcataggtt ataatactta aaaggagagg atagagttga aaacaaatac
    16261 agatgttatt atggagataa ttgattatat agaagaaaat cttacagaaa atctaaattt
    16321 agataaaata gcttatattg ctaattattc aaaataccat ttacacagaa tgtttacaaa
    16381 tgttgtagga tgtactatcc atcaatacat acagaggagg agacttactg aagcagctag
    16441 acaacttata tttacagaca aatatattat agatatagct attacagtag gatattctac
    16501 acatcaatct tttacactag catttagaaa tttatataaa gaatctccac aagtatatag
    16561 aaataaagat gaattttatc ctattcaaca gagatttgtt ttaaatctaa atcatcaaat
    16621 tcaaagcgaa aaatgtattt cttatgcaaa tatgaattat aaacaaagaa gagatgaaat
    16681 caattcttat cttaacttta atattaattg tgaggtgaaa gtagcatgag tttagtgcca
    16741 catgtaattg aacaaacagg tcaaggggaa aggtcttatg atatatattc aaaattatta
    16801 aaagatagaa ttatatttat aggagaagaa attaatgatg ctattgcaag tttagtagta
    16861 gctcaattac tgtttttaga atcagaagac ccagattcag atataattat atatataaat
    16921 agccctggtg gctctgctac atcaggattt gctatatatg atactatgaa ttatgtcaga
    16981 tgtgatgtat cgactatctg tattggtatg gctgcaagta tgagtgcttt tttacttgca
    17041 ggaggaacac atggaaaaag atgtgcttta cccaattcag agattatgat tcatcagcca
    17101 atgggaggag ctaaaggtca agcaacagat gtaaaaatag ctgtagataa tatattgaaa
    17161 ataaaagaac gattagataa aattctttct gaaaatacag gtaaatcaat agaagatatt
    17221 agaagagata cagatagaga taattttatg actgcactag aggctaaaga gtacgggctg
    17281 attgattata taatgaatag gaatgaatag gaatgaataa agtatcaaag tatcatatta
    17341 aaatgtctgt tttacaaata tatatataat attaaataag agtgtctcaa aatgaacttt
    17401 ttagtttatg ggacactctt ttttgtatga aattaaatat ggttttatca tttcaacaat
    17461 tattaccaaa tttcaagttt aataaattct actataaaaa atacataaaa gataaggttc
    17521 tttagtaact ttctgtcgtc aaaagttttt ataaatttaa taacaaaaca agagaaaata
    17581 ccatatatta cttatgtctg caatatatag aagacaaagg agttgtacat tatgattgca
    17641 ataagtttgt gcatgattgt taagaatgag gaagaagtta taggcagatg cttagaatgt
    17701 gtaaaggata tagtagacga aattataatt gtagataccg gttctacaga ttccacaaaa
    17761 gaaatagtct caaaatatac agacatggtg tacgatttcg aatggataga tgatttctct
    17821 gctgcaagaa atttttcatt ttctaaagct tctaaagact atactatgtg gcttgatgca
    17881 gatgacataa ttttagaagc tgatagagaa aaattattaa agattaaaga aagcttggat
    17941 acttccattg atattgttat ggcaaaatac aatgtatcct ttgatgaaaa tggtaaccca
    18001 actctctcat attatagaga acgattgttt aaaagaagtt ctaatcataa atgggttgac
    18061 cctattcatg aagtagtacc tctttttgga gaggtatttt attctgacat tgcaatatct
    18121 cataaaaagc ttcatagaca ggaccctcta agaaatctta gaatttttga aaaaatgatt
    18181 tcagaaggaa aaacattgga gccaagacac caattctatt actctagaga gttgtactat
    18241 aatgctaggt ataaagaagc aatagaaggt tttactaagt ttttagactc atcaagagga
    18301 tggattgagg attgtatcag tgcctgcaga gatttagcca catgttatta cttaattaat
    18361 gatgaaaaaa gtgccttata ttcattgttt agaagtttcg aatttgatga gccaagagca
    18421 gaaatttgtt gtgacatagg aaagcatatg tttgatagac aaaaatataa agaagccatt
    18481 ttttggtata aggtagcatt aacaagagat aagaatgata ctaatggagg ttttaagtca
    18541 aatgattgtt atggatatat accatctata caattaagtg tctgttatga caggttagga
    18601 gaatcagata aagctattta ttatcatgaa aaaacaaaag aaatcaaacc taacgatagt
    18661 gctgttttgc acaatgaaaa ttattttagt aaatttaaaa atagttgata ggtcacaatc
    18721 atactaaatt tgacatatta tatatagagc ttaaaagctc aaatatatca ggaggtgctt
    18781 ttaataatga gtagaaataa atattttgga ccatttgatg ataatgatta caacaatggc
    18841 tatgataaat atgatgattg taataatggt cgtgatgatt ataatagctg tgattgccat
    18901 cattgctgtc caccatcatg tgtaggtcca acaggcccaa tgggtccaag aggtagaacc
    18961 ggcccaacag gaccaacggg tccaacaggt ccaggagtag ggggaacagg cccaacagga
    19021 ccaaccggtc cgactggccc aacaggaaat acagggaata caggagcaac aggattaaga
    19081 ggtccaacag gagcaacagg gggaacaggc ccaacaggag cgacaggagc tatagggttt
    19141 ggagtaacag gcccaacagg cccaacaggc ccaacaggag cgacaggagc aacaggagca
    19201 gatggagtaa caggtccaac aggtccaacg ggagcaacag gagcagatgg aataacaggt
    19261 ccaacaggag caacaggggc aacaggattt ggagtaacag gtccaacagg cccaacagga
    19321 gcaacaggag taggagtaac aggagcaaca ggattaatag gtccaacagg agcgacagga
    19381 acacctggag caacaggtcc aacaggggca ataggagcaa caggaatagg aataacaggt
    19441 ccaacaggag caacaggagc aacaggggca gatggagcaa caggagtaac aggcccaaca
    19501 ggcccaacag gggcaacagg agcagatgga gtaacaggcc caacaggagc aacaggagca
    19561 acaggaatag gaataacagg cccaacaggg gcaacaggag caacaggaat aggaataaca
    19621 ggagcaacag ggttaatagg tccaaccgga gcaaccggag caaccggagc aacaggccca
    19681 acaggagtaa caggggcaac aggagcagca ggactaatag gaccaaccgg ggcaacagga
    19741 gtaaccggag cagatggagc aacaggagcg acaggggcaa ccggagcaac aggtccaaca
    19801 ggagcagatg gattagtagg tccaacagga gcaacagggg caacaggagc agatggatta
    19861 gtaggcccaa caggtccaac aggggcaacc ggagtaggaa taactggagc aaccggagca
    19921 acaggagcga caggtccaac agg
//
LOCUS       DAEQJM010000063        19938 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.063, whole genome shotgun sequence.
ACCESSION   DAEQJM010000063 DAEQJM010000000
VERSION     DAEQJM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19938
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.063"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(384..1787)
                     /locus_tag="KRQ43_002881"
     CDS             complement(384..1787)
                     /locus_tag="KRQ43_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2743226.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            2664..3173
                     /locus_tag="KRQ43_002882"
     CDS             2664..3173
                     /locus_tag="KRQ43_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBH2743227.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            3201..3395
                     /gene="rpmI"
                     /locus_tag="KRQ43_002883"
     CDS             3201..3395
                     /gene="rpmI"
                     /locus_tag="KRQ43_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBH2743228.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            3451..3807
                     /gene="rplT"
                     /locus_tag="KRQ43_002884"
     CDS             3451..3807
                     /gene="rplT"
                     /locus_tag="KRQ43_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBH2743229.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            4117..4662
                     /locus_tag="KRQ43_002885"
     CDS             4117..4662
                     /locus_tag="KRQ43_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743230.1"
                     /translation="MNEKLMDCFVNPIKCKLLLEVFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKEGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            4649..4822
                     /locus_tag="KRQ43_002886"
     CDS             4649..4822
                     /locus_tag="KRQ43_002886"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743231.1"
                     /translation="MKGNKSDLHEVEPIYTENRFMIYICIQSKVSLHGLYFIVPFHPM
                     TWSGTMKFFNFSY"
     gene            5098..7023
                     /locus_tag="KRQ43_002887"
     CDS             5098..7023
                     /locus_tag="KRQ43_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH2743232.1"
                     /translation="MKIKFVIMPLVIFLIVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFISNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWIINDKFSKTIEVE"
     gene            7424..9328
                     /locus_tag="KRQ43_002888"
     CDS             7424..9328
                     /locus_tag="KRQ43_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH2743233.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFKQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEGKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
     gene            9716..10495
                     /locus_tag="KRQ43_002889"
     CDS             9716..10495
                     /locus_tag="KRQ43_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH2743234.1"
                     /translation="MNYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKVFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVVLGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDVVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(10805..11626)
                     /locus_tag="KRQ43_002890"
     CDS             complement(10805..11626)
                     /locus_tag="KRQ43_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HBH2743235.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDITVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLEDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(12351..13169)
                     /locus_tag="KRQ43_002891"
     CDS             complement(12351..13169)
                     /locus_tag="KRQ43_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2743236.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNNTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDSVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            13337..13918
                     /locus_tag="KRQ43_002892"
     CDS             13337..13918
                     /locus_tag="KRQ43_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2743237.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            13915..14109
                     /locus_tag="KRQ43_002893"
     CDS             13915..14109
                     /locus_tag="KRQ43_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743238.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(14273..16015)
                     /locus_tag="KRQ43_002894"
     CDS             complement(14273..16015)
                     /locus_tag="KRQ43_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HBH2743239.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEDLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            16444..17820
                     /locus_tag="KRQ43_002895"
     CDS             16444..17820
                     /locus_tag="KRQ43_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBH2743240.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            18131..18802
                     /locus_tag="KRQ43_002896"
     CDS             18131..18802
                     /locus_tag="KRQ43_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBH2743241.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            18993..19790
                     /locus_tag="KRQ43_002897"
     CDS             18993..19790
                     /locus_tag="KRQ43_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBH2743242.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         7671 a         2309 c         3225 g         6733 t
ORIGIN      
        1 aagtgataga tacctaatta agttgtagat atctgataag aaatttttaa gttttcaatc
       61 gttctaaatt gtgagtataa aaatctacta aatttagtta tgtaaaatat aaattataag
      121 tgtagaaact aggctactag cttttatacc acttcaaaca ttactggaag tagttaagtt
      181 tacagcagtt tagttttatg tagatataat attctgtaaa tagacaaaat taaaatatgt
      241 aattaaaata tgtaagtgtc tcaaaatgaa atttttaatt tatgaggcac ttttttgtat
      301 aaaatcaaat atatttttat aactttaaca ataaaaagag gcttatctct attttgagac
      361 agcctcaaat ttttaaaact atattagttt acagcttctt ttcctatcaa atcttttaac
      421 tcttcatgag tcatagtttc tttttcaaat aagaatttag aaacagaatg taaatcttca
      481 agattatcct ttaacatctc taaagtctct ttataacaaa tttcaactat acgatttgct
      541 tccttttgaa ccttatcaca taagaaagtc ttatcatttc catcaatagt cataaatcct
      601 aagttactca taccatattc acaaaccatt tggttagcta tttcagtgac tttctttaag
      661 tcgtcctttg caccagtaga tttatgatta aatattaatt cttctgaagc ctttccagca
      721 agtaatattt ttatttttcc aatcaactca tccttagtat aaatatatct atcttcatca
      781 ggtaattgaa gaacataacc taatgcttgt cctctaggaa ctatagatat tttttgtata
      841 ggacaaattc ctactatatc acttacaaga gcatgtccag cttcatgata tgctactatt
      901 tttttctctt tttcaaccaa tgcagagttt ttagattcta gccctgcaat aactctttca
      961 agtgccttgt caaaatgttc tgatgtaata cactcactgt catctctaac tgcaaatata
     1021 gctgcttcat ttgctatatt tgaaagatga gccccattga aaccatgagt ttttttagct
     1081 aaaagttcta gatttacaga tttgtctata ggtttgtcat ctgtatgtac ctttagaatt
     1141 tcaaatctag tgtgatagtt tggtgcacct atatgaatgt gtctgtcaaa tcttcctggt
     1201 ctaagtaaag cttcatctaa taagtcaagt ctattggtag cacctattat taatacattg
     1261 gaatctttat taaatccatc catttcaact aaaagttggt ttagtgtttg gtctttttcg
     1321 ttgttacttt caagatgtct ctttgctcct acagcatcta tttcgtctat aaatattata
     1381 cttggagctt cttttctagc tttttcaaat agagttctaa ctctttttgc tcccacacct
     1441 acatattttt caacgaactc tgaaccagta acattgaaaa atgatgagtt tgtttcacca
     1501 gctacagcag atgcaagtag ggttttacct gttcctggag gaccataaaa taatactcct
     1561 ttaggtattt ttgcacccat tttttgatat ttttgtggtg acttcataaa atcgactatt
     1621 tcaaatagtt cttcttttac ttcgtctaat ccagcaacgt ctctaaatgt agtctttggt
     1681 tttgtagaaa gtgaatcatc tgtttgatta tctctttcca tttttgtctg tgcaaagaca
     1741 ggagctggat tgttgatttt cttaaaaaag ttgtttagca ttttcatatt cacacctcag
     1801 gtaattaatt attgttaatc aattttatat tttccatatt tactattttt tattatttat
     1861 ttttcatgga aaaaatatac atgttatcta aataaaaata aatttgtaag atgtatgaaa
     1921 aaatgaattt atgtatatag agatttctac ttatgtattg aataaagtat tacaaattat
     1981 aaattatgta ttgattatat attgagtaaa gtattataaa gcatgtattg attaagtatt
     2041 tattaagtat tgaataaaat attacaaatt tagttgaaat gaaaatgata aaaaatgttg
     2101 tgctatattt tacaaatcat ataaatagag aaattgttgt agcacaaagt aataggtagt
     2161 atattagaat ataatatagg atttgttgtg tagtatagta gcatattaga atataatata
     2221 ggatttgtta tgtagtatag tagcatatta gaatataata taggatttgt tatgtatata
     2281 gtagcatatt agaatataat gtaggatttg ttatgtagaa tatatagagt catgtagaat
     2341 ataaatatat aaaaggattt tgggtataaa tttaaaaatt aatagcaaaa tgagtagtat
     2401 agacatataa ttagtagtag gaagtaatta aatttttcct aaacaaaaaa aatagttgca
     2461 aataatttga ttaagtgata tagtaaataa ggtaagaata aaacaaagaa gaagtccgct
     2521 tctcacctta cgccggaggt tagtaaggta aatataagtt aaagcttaat tttaatttaa
     2581 gtttgtttaa atttggtaac ttatattgcg gatgattacg tcatccgctt tttattttat
     2641 aaaaattttg gaggtgtcct acaattagca aagaattagc aatcaatgaa caaataaaag
     2701 ataaggaaat aagagtcctt tcaccaacag gtgaacaact tggagtaatg cctactaaag
     2761 aagctcaagc aatggctaat agcaaaaact tagatttggt tcaaatctcg ccgaatgcga
     2821 atccaccagt atgtaagata atggattatg gaaagtttag atatgagcaa gcgagaaaag
     2881 agaaagaagc taagaaaaaa caaaaaacta tagttgtaaa agaagtaaga cttagaccag
     2941 gtattgaaca aaatgattta aatacgaaag ctaataatgc tataaagttc cttaaaaaag
     3001 gggataaagt caaagttgaa cttagattta gaggaagaga attaggacat aaagacatag
     3061 gtaaagaagt tatgcttaag tttttagata taataaaaga gtttggagaa ccaacaaaag
     3121 cccctgcatt tgagggtaat aatatggttg taattataga tccaaaaaaa tagatgatta
     3181 actgagagga ggaatttgtc atgcctaaaa tgaaaactca tagaggtgca gcaaagagat
     3241 taaagaaaac aggaactgga aagttaaaga gagctaaagc ttttaaaaaa catatattaa
     3301 ctaaaaaatc tgcaaaaact aaaatgaact taagaaaatc aactttagta agtgatggag
     3361 atgccaagag aatagcacaa ttattaccat actaagatac agattgtaaa taataactat
     3421 agaagaggga tataaaagga ggtcataacg atggcaagag ttaaaaaagc tatgaacgct
     3481 cgtaaaaagc ataagaaaat attaaaactt gcaaaaggat tcagaggatc tagaagcaaa
     3541 ttatatagac cagcaaatac attcgtaatg aaagcattaa aaaatgctta tataggaaga
     3601 aagttaaaga agagagactt cagaaaactt tggatacaaa gaataaatgc agctgctaga
     3661 atgaatggaa tatcttattc aagattaatg aatggattaa aattatctgg tattgaagtt
     3721 aacagaaaaa tgttatctga aatggctata caagacccag aaggatttgc aaaattagca
     3781 gaagttgcta aagcaaaatt agcttagtat tgaatcatga gatgtaaagt ctttgagtta
     3841 tataaataat tcaaggactt ttttattttt tgaaaaatac ttattagtgt catgtacaac
     3901 caattttata atgataaata aaataagcaa tacaatagaa ttttatgaga tttattataa
     3961 gaattgttac aattatttat catagctata aaaagtcata gtaaaaatga tattgatgta
     4021 tgtttatata tgtataaagc tttcaatcaa tcttgaatta atattatcaa catgataata
     4081 ttatcttatt aataatataa ataaggggga gataatatga atgagaaact aatggattgt
     4141 tttgtaaacc caattaaatg caagttattg cttgaagttt tttcaaataa tcgaactaca
     4201 gctaaacaat taggagaaaa atttcaagat atatcaaagg caacacttta tcgttacctt
     4261 aataaaatgt tgaaagatga tattataaaa gtggttgaag aaaataaaat aaggggaact
     4321 gttgaaaaag tatatgctat gaagttagat atagctgatg atgtgaacaa aattatagat
     4381 gagaactctg gagaagaata tgctcaactg tttactcaat atatgatggg atttttaaga
     4441 gaattttatg aatacgctga aagaaaggaa aaggatatcc taaaagaggg ttcaggattt
     4501 tctgtctgtc cagtatatgc tagtattgat gaaatagttg aagtgagtaa aaaaattgct
     4561 agtatactag aacctctaag aaataactcg cacgaagaag gcagaagaat gcattctata
     4621 ggagtgataa tcactccacc taaagaggat gaagggaaat aaatctgatt tacatgaggt
     4681 agagccaatt tacacggaaa atcgttttat gatttacata tgtatccaga gcaaagtatc
     4741 tctgcatgga ttgtacttca ttgtaccatt tcatccaatg acttggagtg gaacaatgaa
     4801 gttttttaat ttttcatatt aatgcctaaa gaaatgaact ttagaccaca tatgcaatta
     4861 ggctacatta tacaattaga ccagatatac agaataaaaa ttagtatttt tatagcagat
     4921 aaattgactg ttattcttct taaaaatcat ctattagtta ttgttagcat attgaaagaa
     4981 attatagtaa tccattgaat aaatgaatat tgcccataat catataaact gctatagttt
     5041 aaaataaagc aggacgttaa attttatagt aatcttaaaa tttaagaggg ggattttatg
     5101 aaaataaaat ttgttattat gccattggtg atatttttaa tagtattatt tgtggggtgt
     5161 caaagtacaa aagatacaga agttaaagca aaagatacag aaattaaaat attaggtaca
     5221 ggtgatttgc attcaatttt gacagactct atggtttcat atgtaaatga ggaaagggaa
     5281 aagaataaaa atctgcttat ggtagatgcg ggagatttct atggtacaca aagtagagaa
     5341 atgtgggaat ggtcttctgg aaaaaagtta attaatatta aaagaaatgg tagagcagag
     5401 tatgatgaca taattaaaag tagtaaagat gaagtaccta tagttaaaga tatggcaaag
     5461 ttgaaatatg atgctgtagt tttgggagat aatgaattta tttcaaatga taagcaaagt
     5521 cttgataaac tagtttctga ttttaaaaat aataatatgc cattggtatc agcaaatata
     5581 tatgaacaat ctggagaaaa ttatgtacaa ccatatgtaa tgaaaaatat taagacagat
     5641 gagggcaatg taaaagttgg aatactaggt cttactataa aagaagtagg ggaaaccctt
     5701 ggtcttgagg attttgaaaa ggataaaaaa gctagagagc ttggagaaca agctgattac
     5761 aaaggaaaat tatatgcaaa tgatttagta gaagatgcaa agaaatggat aaaagttatg
     5821 gaaaaagaaa gtccagacat aatagttgca gttgtacact caggggaaga acctaaaaca
     5881 gatagaaatc caggaaatag aataaaagag ttagcaacta cagtggatgg aatagatgca
     5941 attgtagctg gtcatactca tgaaaaaata gatgaacaca aatataaaaa taaatctgga
     6001 gatgaagtaa ttgttacaca accaggttgg catggagata gagtatcaga gattaatttc
     6061 aaattaaata aagagaatgg aaagtgggac ataaaggaaa agtctagtaa attaaaaata
     6121 attgataaag aagtaagtat agttgctact gcagatttac attcacattt ctctgataaa
     6181 ttaacagttg accttgttaa tgaacgtagt aacccaattg aacctgttgt agtagatgca
     6241 ggcgacttct tagaccctca aacagatgaa atgactcaat ggtataaaga gtggaaaagt
     6301 ataagagata ataatagtga taaaacgatt agtagatgcc caatggtcat ggatatgaat
     6361 cagggaatgt atgatgcagt agtacttgga aatcatgaat ttgtatctga aaaagatgaa
     6421 ttttggtcag atgaacgcct tttagatgct gttatagagg attttgaaca ggtggcaatt
     6481 tctgtgttat cagcaaatat atataggcaa tctggtaaaa attatgttaa accatatatt
     6541 ataaaagatg tggagacgag tgaaggtaat gtaaaagtag gaatattggg acttactata
     6601 aaagaagtag gtaaaggtct taaaaatgta aacttacaag agcaatttca atataaggat
     6661 aaattgtatg caaatgattt agtggaagat gcaaagaaat gggtaaaagt tatgaaaaag
     6721 aaaaaaccag atataatagt tgcagttgta cattcaggag aagaaccaaa aaatccaaaa
     6781 cacccaggaa atagaataaa agagctagca actacagtag atggtattga tgcaattgtt
     6841 gctagtcata ctcatgaaaa aatagatgag catgaatata aaaataagtc tggagaaaaa
     6901 gttatagtga cacaaccagg tgagcatggt aaatattatt ctaaaattac ctttaaagta
     6961 aataaagaaa agggttcgtg gattattaat gataaattca gtaaaacaat tgaggttgaa
     7021 taactttata aaatttatag ataaagtaaa ttatctgata ttgacatgat atataagata
     7081 aagtttctaa tattagtata atgcataatg tgaaatattt taataataag agaataaaca
     7141 agacaaataa aaatatttta acatgtaaga tatagtatga actattatac taatgcttac
     7201 tttataattt gaacatgtta gaataagtct tatttgaaaa ttttagtgta ttagagtaag
     7261 tattatttta ccagtaaaaa atattgagaa ctatatgtag atttgcttaa aaaggaattt
     7321 acatatagtt cttttcgtat aataaatagt acaatcttat atggtaaaga taaagtgtga
     7381 tattaaattt tattatcatc caaaatctaa ggaggagtct cttatgaaaa taaaatttat
     7441 tatagtagca tcaataatat ttttaatagt attacttgtg gggtgtcaaa gtactaaaga
     7501 cacagaaatc aatgtactcg ccacaagtga tttacattca attattccag ataatttaat
     7561 ttcctatgta gaagaggaga gaaaatatga tgagaatcta cttatggtag atgcaggaga
     7621 tttttttgac atgcaaagtg gtgagatgaa taagtggttt actggtcaaa aattagtaag
     7681 atttaaagat gggataccag agtacaaaaa aatagctgaa ccacgtgaag gagaagttcc
     7741 attggctaaa aaaatggcaa agctgaagta tgatgcagtt acatttggga atcatgaatt
     7801 tgtatctaat gacaagcaga gccttgataa attggtttct gattttaaaa ataacaatat
     7861 accattagta tcagcaaacg tatatgaaca atctggagaa aactacgtaa agccatatgt
     7921 aatgaaaaat ataaatactg acaagggaac tgtaaaggtt ggtatacttg gtctgactat
     7981 aaaagaagta ggggaacgtt caaggtttaa aagttttaaa caagataaaa aggctagaga
     8041 acttggggaa caacctcaat acaaagggaa attatatgca aatgatttag tagaagatgc
     8101 aaataagtgg gtaaaggtta tggaaaaaaa agaaaagcca gatataatag ttgccattgt
     8161 acattcaggt gaagagccaa aaaatcctaa aaatccagga aatagaataa aagaactagc
     8221 aacaactgta gagggaatag atgctattgt agcaggtcat acacatgaaa aaatagaaca
     8281 gcatacatat aaaaataatt ctggtgaaga agtaatagta acacagcctg gagctcatgg
     8341 taatagtata tcaaagatta attttaagtt ggataagaag aatgataagt ggtttataaa
     8401 agacaaatat agtgaattaa aggtttttgg aaaggaagta aatataatta caacttctgg
     8461 tctgaatcca aaattttcag atgaaatggc agttaatttg tttaatgaaa gagatagaga
     8521 tgttcaacct atctttatag atactggaga ttttttaaat actaatacaa aagaaatgac
     8581 taagtgggct aaagagtggc aatacaatga aaataaaggc atctataaaa aaataaatga
     8641 atggccaatt gtatatcttg gttatgatgc tgtagtactt ggtagccatg aatttacaga
     8701 ggataaagag acttttgagg gaaaaaaatc tacattggat tatattatag aaaactttga
     8761 agaaatgaag ataccagtat tatcagctaa tatatatgat gaatctggag aaaattatgt
     8821 aaaaccttat ataattcata atgtagaaac tagggaagga aatataaagg ttggagtatt
     8881 aggtcttact actactgata aggatgaaga agacttaagt agctcaagct taagcaaaga
     8941 ctcaaagact tcgaaaattc ctgaagaaac aggaaagtta tatactaata atctagtaaa
     9001 agatgcaagc gaatgggtaa aagttatgca aaaggaaagt cctgatgtga ttgttgcagt
     9061 tgtacattca gataataata gtactctaaa aaatccaagt agtgaagtca aaaaacttgc
     9121 aatgtcagta gatggaatag atgctattgt tgtaggtcat acgaaaaata aggtagaaga
     9181 acatatttac aaaaataagt ctggagatga ggttatagta acacaatctg gagaagattg
     9241 ttattcaaaa ataagtcttg aactaagaaa agaaaatggc aagtggaata tcataaacaa
     9301 atatagtaaa gcaataaaaa tgaagtgaat ttattgatat ataaaccatt attaacactg
     9361 atttttataa tataataaat actgattcta caatataatt aacactactt ttttaaatat
     9421 aataaatact gattctacaa tattattaat actacttttt ataatataat caatactact
     9481 ttttacaata taatcaatac tgattctata atataattaa cactactttt taaatataat
     9541 caatactgat tctataatat taacactatt ttttatgcta tataacaatt attgaaaatg
     9601 atataaatat aatatctcaa atgatatgaa tataacatct gaatagaggg tgttttattt
     9661 gtaaaaaata agtttacagt ttgagcgtat aaacttatgg taaaggagaa taattatgaa
     9721 ttataagaag attgcaatta taacgggtgc taatagtggt tttggtaaag agtttctaaa
     9781 gttattaata aatgaagaag aaataacaga aatatgggca gttgcaagaa acaaggcgag
     9841 attaaatcaa ttagtagatg aatttggaag taaggtaaaa gttttttcaa aagatttatc
     9901 aaaaatagaa gaagtaaaag aaattggtac atttttaagt aaagaaaatg tatgtataaa
     9961 ataccttata aacaatgctg gttttgcaaa attctgttca tacaatgatt taagtataga
    10021 tgaatctatt aatatgattg atttaaatat tagtgctgtt gtagtattgg gacttatatg
    10081 tattccatat atgcaaaagg gaagccatat tatgaatatt tcttcacaag catcattcca
    10141 gccattgcca tatcaaaata tttatagttc aactaaagcg tttataagaa attatacaag
    10201 agcattaaat gttgaactta agagtaaagg gataaatgca attgctgtat gtccaggttg
    10261 gatgagtaca aatctattta agagaggtat agttgtagct gaaaaaggga caaaaaattt
    10321 cccaggcata gtgtctccag acgttgttgc caaaaaagca ttgaaggatg caaagaaaaa
    10381 taaggatatt tctgtgtatg gtataaatac aaaatccagt catttattag caaaactatt
    10441 gccacaaaaa atgatgatga aggtttggtt aatgcaacaa catattaagg aataagagtt
    10501 tcggtaatta agtatcagtt ggagattcaa tctattatat attataagaa gttttgttga
    10561 gcaaataata attgtgacaa aacggcttat ctagtgccga taagccgtct ataatgtata
    10621 aaaaatatat ttttgatttt actttattta gatattgaag tattaaaata tgtaggactt
    10681 gaaattttat aaagataaat actatgatat tttgtaaaaa ctgagatatg ttgatattac
    10741 atagtttaac tatactgtta aattgaagtt ttcttatttt gcattatgct tattacttaa
    10801 tgatttagac tataatttcc ataccatcat atgcaaaata aatgttatca agtttctttt
    10861 ctaattcact gtaataacca tatgattttc cccacatttc gtcaatatgt gtaatgataa
    10921 tctttttaat tctataatag tttttaattt caacaatctc atctaaagta aatatttcat
    10981 ctttaaatgg tgtgtcttca agttttgtac catcatttaa tataccatca tcagaaacta
    11041 gacttattat taaaacatca gcatcaaagt acatatcact atgagtaaat ggcttgggat
    11101 tacagcaggc atatatgact tttttttcat tctctttgat aacatagaag gttatattcc
    11161 tgtctgggtt attgttaatc aaatcaatat caaaattatt tatctttaca tgcgaagttt
    11221 cattaataga aatgcaattt ataacatcac cataatattt aagacaatcg agattcgttc
    11281 ggtttatatc ttcaattact tcaggaagag cataaaagcc aattggatta ttttctcctg
    11341 tgataaagtc acatcctatt ttttcgacaa ttctaatacc cttaacatgg tctgggtcat
    11401 ggtgagaaat tgaaatatgt tttacttccg atattttttg tctgttacaa gctactgtaa
    11461 tatcttcagg tgtgtctatc agcattttta tatcatcaat atataaactt ggtcctaatc
    11521 gttcatatct tccgcctttt tgcctggctt cttcacatat tttgcattta caaaatgaac
    11581 ttggaataat tgacataccg ccactaccaa caatttttaa tttcaaagtt attacaccac
    11641 cttctaaaaa tattagatta tataaataat ctacaatcac aactgattaa caaaattatg
    11701 agttaataaa ttatatcaca tgtaaatatg aaagaatagt atgaaatttt tataagatta
    11761 tattaaatat ttctcaatga aattgacttt gtatatgagc cgaatgactt tattcaatat
    11821 agataagaca tttttcttgt aataagatat gattattcta taaggttcat gtaattttga
    11881 tataaaatat tgattaataa catatatgtt attggtgaac atatttctat agaatggaat
    11941 atataatttt ttatatttat cattgtatta ttatacaaag aaagttaaaa agagtagagt
    12001 acaaaggaat tatttgtact ttactctttg ttttgttaaa aactaattta tattagtgat
    12061 tcaaatattt aactagagta taagggttgt atataatctt ataagtaatt tatctgacaa
    12121 attaagataa tatcctaatc aaattctagt cattcgaaca taacatcaca agtgatttat
    12181 ctgacaaatt aagataatat cctaattaaa ttgtagatat ttatacataa cactaaaagt
    12241 aatttgttta acaaattaag ataatatcct aattaaattg taggtattta tacataatac
    12301 taaaagtaat ttgtttaaca aattaaaata ttatccaatt aatataaaaa ttacttcttt
    12361 ttaactggga agcatacctc tgttacccaa ttatcaggat tactatcgtt gccaggactt
    12421 acatgataaa tattaaacat aggaccatcc acatcatagt tattatctga tatccaatta
    12481 ccaatagcct cacaagcgtc tgcaacttga ttgaaatttc cattaacaat tgcagttgca
    12541 gcagtcacac ttggaacagt cttaaattta acatgttcag tatctttata ctttccagat
    12601 acagcaactt gtacttcaac atctacagaa tcttctttat atccagtatc ataaaagact
    12661 gctttagaat actttggggg ttcaatttga acattctggt cttttgtctc taaaaatgct
    12721 tgatgccata acattccttc gtcttgataa gttggtataa cccttctaag tgtcatcata
    12781 tattttggtg caaaattctt tatagttaca tcataatttt tcataatatc atttcctcca
    12841 attcttttaa tagtggtttc tatttttaat agttttttct gtgtatcttc taattgttct
    12901 tttacttgag aatggtggat atttagatat tttataagac tttctttatc gttatattct
    12961 gtcaaaattt cttttataga atacaagcca aagcccatat cttttagtgc atggattcta
    13021 tttgtagtag aaagttggtc tgcactatag tatctatatc cattagtgtt attcgtatga
    13081 gaaggagtta aaagtcctat ttcatcataa tgacgtaaca tacgaatact aattttactt
    13141 agctttgaaa aatcgcctat cttaaacatg tttttgtctc ctttataaag gtacttttag
    13201 cttaatatta atataaacca tatcataatg ttagagtcaa ctaaaattat aattaaatta
    13261 tattgacata tgatgaaaaa aatattatac tgaacatgtt cagaacctaa aatgttaatt
    13321 attttggagg tctattatga aaagtaatga taaagatgct agagaacgta taattgaagt
    13381 tacattgaat cttttaaatg aagtagatga tattgaggag attacagtta gaaaaattgc
    13441 tgagcgtgca aatgttggag ttggtttaat aaattatcat tttaaaacaa aggataattt
    13501 gttgagtact gccataggag atgtgatgtc aaatataata gcagagctat atgacgatag
    13561 tgtatatact ctaagaccta ttgaagattt gaaaaattta ttaaaaaaat tgtgtgatac
    13621 tggattacat tatgaaaaag tgcttccttt tgtgttgaat caatgtataa ccaatggaga
    13681 tatgcaagca gaacttgata ttgtccctat gcttcgtaaa atttttggaa ataaaaaaga
    13741 tgaaatgagt ctaagaatca ttgccctgca aattatttta ccaatacaga tttctgcttt
    13801 atctacagaa tcatttcagt tatacagtgg tataaatata aagaataaat atgagcgaga
    13861 taaattcatt gatattttaa tagaaaatat tattggagag gatgttgatg taagatgaaa
    13921 attataacta ttggttcaag tcttatcact gttttacttt ttctttcaac tatggtttgt
    13981 gggttctgga ttaagaataa taaggtaaca gatgcaagtt ctattaagtt ccatatgaat
    14041 agtgctattt ttacagggat atttttattg atttccacaa tccttttaat tatatatata
    14101 aaaaaataat aatattatta ataaataaag tatcagaaat tataaagaca agagtcttaa
    14161 aaatttctga tactttacca cataatttta ttaaacatta attgtgtgtg aaaaaatatc
    14221 acttatttca atctaatact aaatcttaag agtgagtata aagtattaga aattaagaag
    14281 cattttttag ttcaagtgga ttatctatac caaaataatc atataaagta gagcttattt
    14341 cctctaaatt tccatcttgg aaaggtaatt gtaaatttac cttttctacc acatctttaa
    14401 atccagcatc agtattttga tttaaaaaat ccatatatac atcaacagct tttctgtaat
    14461 cttcttgtga taattgccat atctgaagtg atacatcaga tgcaagacca taactcaagt
    14521 aataaaaagg aacttggaag ttatgagata caagtatcca aaaaggagca tttttttctc
    14581 taagtatatt attggaaact ccatattctt cctctaaatc aaaaaacaat ttattgatat
    14641 catttagact catatatgga ttcttgtata taatttcttg aaattcatca taaagacaag
    14701 catcaataat agtatttaaa acaatcgata agtgttcttt ttttatagct tcagattgtt
    14761 taccaaaaaa atcatcaaaa tatttataaa atagaatttc taaagatgtt gaatgaactt
    14821 cacatacatc tatacttggt tgcatcttat tatttaagtt aatactgttg tagtaattat
    14881 aaaaatgacc aaactcatga gcaaaactag taacacctaa aaaagaattg tcccatgtat
    14941 taaacaagaa aggtgcttta tatttattta tataagtagt atatcctcca ggcgatttgt
    15001 tttttccaga agaataatcg tacaagtcat attttttcat atagtcgaag ctctctttta
    15061 gttttggaga tatatcttca agtactttat caaacttcct aaatgagcga tttttatata
    15121 ctttaatata aatagaagaa tcagatggtt tagatgaaat ctctctatat aatggaacta
    15181 tgtaatcttt tacatcttgt ctaaattttt tagcttcttc ttgagaatag tctttgttta
    15241 ggttcatata ggcataatct atataattct taaatccttg cttacttgct atttcagttc
    15301 ttgtctgtat aagttctaag aatatgttac caaatatagg attgtatttt tttaagtaat
    15361 ctgaataaat tttcacatat tcttcagggc taagatttgg tcttgacaag gcttcttcaa
    15421 agtctacctc tataccatct attgatactg tagatttagc taataagtct tcatatttta
    15481 caactaggtc ttgctctttt ttaagtaaat cttcaacttc tttagaatta agttttccaa
    15541 tgttctttag ataattaaat gtatcctttc caagttcttt ttctaattct ttagagaatt
    15601 tagaagttac aaatctatct tgaaagtctt tgtatgacat gtcaacatct actgatttac
    15661 tcataagata cttatattcc ttagagtaaa attcgtctga tgaatctatg ttatttctaa
    15721 tttttgctat agtaagtgta ctgtaaaaat cctgataaat tttatcaact tcattaaata
    15781 aatttaattg ttccttagct gttttagctg ttaaaagttt gtcgttacac ttgttaatgt
    15841 tttcgcaaat tgactgtata ttaggacgct tatattccat tttttcaaaa ggaatagttc
    15901 ctctaacaga atcttttttt gtatcattag tataatttct tatgtatgat gcaaatataa
    15961 taaaaactgc aattaaaatt agaaaaacaa atattttctt cttggattta accataaaaa
    16021 tcctccaatc atggatatag ttattaatta ttttactata ttaaatataa aaaatgcatg
    16081 ttaagaaaat ttaacataaa gatatagata agattataaa taatataaaa aatttaactt
    16141 caaaaaagta tatgaaattt atactggtaa aatgataaat aaattttaag tacaaaatag
    16201 taaaagctat gatagtttta gacccattat atgtaaaaaa tatagatgtt tttggtgcaa
    16261 tttaaattaa aagatatata taaaaattta aaatattcca aacagaaatt ataaaaatta
    16321 ctatcattgt ctttatgcaa tatttatact ataatagaat aataatttag aggaaagctc
    16381 taaaaataaa caaattaagg gtcttaacag tagtgatttt atgttaagga ggtataaaga
    16441 aagttgaaaa caatagttag aagacttatt ctctacgcag atggaatgcg tcctactcaa
    16501 ataatggtat ctgggtttgc tgcgattatt gtaatcggag cattgttgtt aacactcccg
    16561 atagcgtcgc agagtggaga gagtataggc ttattaaatg ctctatttac ggctacttca
    16621 gcggtttgtg ttactggtct agttatggta gatacagcaa cttattggag tttatttgga
    16681 cagatagtta taataacatt gatacaaatt ggtggtcttg gatttatgac cgtagccaca
    16741 atgttttcac ttatggcacg aaaaaaaata caactaagag aaagattatt aatacaagag
    16801 tcattaaatc aagctgattt atcgggactt gtaagactta caagatttgt attaataata
    16861 accataacaa tagagggaat aggtgcactg gttttatcaa ctgtctttat tccacaattt
    16921 ggtttgtcta aagggatatg gtatagtgta tttcacgcaa tatcagcgtt ttgtaatgcc
    16981 ggatttgact tgatgggcag tgtaagtggc ccatttacat cgttaaattc ttatgtaaac
    17041 aactttacag tatcaatgac tgtttgcgca cttatagtgc ttggagggct aggattccct
    17101 gttgtacttg atattgtaag aaaaagaaga ttttcaaaat taaatgtgca ttctaaggtt
    17161 gtattgtttt caactgctac acttattttt gtgggtgcat tatttatttt tcttatagaa
    17221 tttaatcaaa aagctactat ggcggacttg cctttaaagg gaaaagtact atcagcaata
    17281 tttcaatcag taacagcaag aactgctggt tttaatacac ttgatttagc tactttacga
    17341 gaaagtagtg tatttgtaat gataattttg atgtttattg gagcatcacc tgcatcaact
    17401 ggtgggggta taaaaacaac aacactagct gttttaatca ttacagttag aagttttcta
    17461 tcaggaaaat cagatataga agcttttgaa agaagattag ctccatcaac tataaaaaaa
    17521 tctcttggta tatttgtaat cagtatatca gcagttattt ttggaacatt gattatttca
    17581 ataactcagc ctaattttac attagttcaa tcagcttttg aggttacatc agcacttgct
    17641 acagttggtt caagtttagc tggaactcca aatttaaatg ctttaggtaa gattataata
    17701 ataatcttta tgtttatggg tagagttggt tctcttactt tatttatggc tatactttct
    17761 ggtggtagaa gaaagagtca accaatcaga tatgcagaag gtaaaattat ggttggttaa
    17821 gttaccaagg agtaatataa atttataatg gatttagagt agcactgtaa atctgttgat
    17881 aaaataaatg agcctagatg taattatatg aagaaataaa atcaactaat aaacaaaatt
    17941 aattaatgaa ataaaaaaac agggaaataa aatacaaata aaaaggtaaa tcaaaattaa
    18001 attaatctgt gtatataaaa ttatatattg tgtataagtt ttgtatgtgt aaagtatata
    18061 agttttgtat gtgtaaacaa ttaatttaag agatattata taaattgtgt attagggagg
    18121 aagtttcgag atgaagcaat atatagtcat tgggtgtggg agatttggaa gttcagttgc
    18181 gtctactatg catcttttag gacatcaagt aatggcaata gacaaaaatg aagattcagt
    18241 tcaaagtata tctgacaagg taacccattc acttatagtg gatgttactg atgagcaagc
    18301 gttaaggtca ttaggtttag gtaactttga tgtagcagta gttgcaatag gttctgatat
    18361 aagggcatct ataatggcga ctcttatagc caaagaaatg ggtgtagagt tgataatatg
    18421 taaggcaaag gatgaattac aagctaaagt gctttataaa attggcgcag atagagttgt
    18481 atttccagaa agagatatgg gagtaagagt tgcacacaat ttagtttcgg ataatatatt
    18541 agaccatatt gaacttgacc cagagtattc aattgttgaa atcgtaactc caaatagttg
    18601 ggttggcaag acacttatag agcttgaatt aagagctaga tatgagataa ctgtacttgc
    18661 tataaaaaca ggtaaaaata taaatgttac accttctcca gatgaggaac ttacagccgg
    18721 aagtatccta gttataatcg gtcaaaatac tagtataaca gcgataacat ctggaaataa
    18781 ggggataatt agaagaagat aatttactat ttaatatata tttaattgca atgaaagtaa
    18841 agagtatcat ataattatga atagttatat gatactattt ttatttaatc gaaggtagta
    18901 tttatttgta agattagata aagagaagtt aaattaaaag taaggaggct gtgctaatat
    18961 aaaaatttat aagttattag catttagata aaatgattac aaatataaac agtaaggata
    19021 atgaaaagtt aaagtataca agagcactat taaaatcaaa gaataggaat aaagagtcaa
    19081 agttcataat agaaggatac agaatagtaa tgcttgcact tgaatgtatg gcaaaccttg
    19141 attatgtatt tatcaatgaa gaatttgaaa ataagaaaga acatgtaaaa ctattagaag
    19201 atttggataa aaaaaacaca aagatataca agactactaa taaaaacttt aaagaattag
    19261 tggatacaga aaatactcaa ggaataatag gtgtagtttc atttaagaaa aaaaaattaa
    19321 gtgaaagtat aaataaaaaa gataaatttg tattgatttt agatagaata caagacccag
    19381 gaaatatggg gactataata aggactgctg attctgctgg agtagatgcc ataatagcac
    19441 taaagggatg tgtcgatata tacaacccaa aagtaattag gtctactatg ggttctattt
    19501 ttgatatgaa tataattgat gcttcacaag atgaaactgt ggacatgctt aaatcattgg
    19561 attttaatat agtttcaagt tacttaaata cagaaaattt ttatgacaaa atagattatg
    19621 gttcaaaagt agcattggtg ataggaaacg aagcaaatgg aataaatgaa gaacttgtat
    19681 caaagtctga tattttggtt aagataccta tatatggtaa agccgagtcg ttaaatgctg
    19741 cgataagctc tgctatactg atgtatgaaa taaaaaaata cttaatttaa tgtattgtaa
    19801 taaatataat gtcatgttat aatcttgaat taaatagtag agtatcaaaa atagtcaata
    19861 tatattaaaa aaataattaa attaattata tattagatgt atatcatata aaaaatgatt
    19921 gagttgatta tgtattag
//
LOCUS       DAEQJM010000064        19847 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.064, whole genome shotgun sequence.
ACCESSION   DAEQJM010000064 DAEQJM010000000
VERSION     DAEQJM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19847
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.064"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(28..294)
                     /locus_tag="KRQ43_002898"
     CDS             complement(28..294)
                     /locus_tag="KRQ43_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBH2743243.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(442..1302)
                     /gene="yabG"
                     /locus_tag="KRQ43_002899"
     CDS             complement(442..1302)
                     /gene="yabG"
                     /locus_tag="KRQ43_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HBH2743244.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(1386..2324)
                     /locus_tag="KRQ43_002900"
     CDS             complement(1386..2324)
                     /locus_tag="KRQ43_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HBH2743245.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(2434..2595)
                     /locus_tag="KRQ43_002901"
     CDS             complement(2434..2595)
                     /locus_tag="KRQ43_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743246.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(2605..3102)
                     /locus_tag="KRQ43_002902"
     CDS             complement(2605..3102)
                     /locus_tag="KRQ43_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH2743247.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(3217..3927)
                     /locus_tag="KRQ43_002903"
     CDS             complement(3217..3927)
                     /locus_tag="KRQ43_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HBH2743248.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(4103..4633)
                     /locus_tag="KRQ43_002904"
     CDS             complement(4103..4633)
                     /locus_tag="KRQ43_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743249.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEIVKNVDCN
                     IVQYSNKDERRVKAKANKMAMRLIHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(4650..4880)
                     /locus_tag="KRQ43_002905"
     CDS             complement(4650..4880)
                     /locus_tag="KRQ43_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743250.1"
                     /translation="MSKLVSKVKKDLEIKWLGVDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(4895..6289)
                     /locus_tag="KRQ43_002906"
     CDS             complement(4895..6289)
                     /locus_tag="KRQ43_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH2743251.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTI
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(6415..7668)
                     /locus_tag="KRQ43_002907"
     CDS             complement(6415..7668)
                     /locus_tag="KRQ43_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2743252.1"
                     /translation="MENKSNFKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALSLS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGVLGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(7719..8873)
                     /locus_tag="KRQ43_002908"
     CDS             complement(7719..8873)
                     /locus_tag="KRQ43_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH2743253.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRKLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIKKLK"
     gene            complement(9432..10001)
                     /locus_tag="KRQ43_002909"
     CDS             complement(9432..10001)
                     /locus_tag="KRQ43_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH2743254.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            10204..10431
                     /locus_tag="KRQ43_002910"
     CDS             10204..10431
                     /locus_tag="KRQ43_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH2743255.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(10650..11393)
                     /locus_tag="KRQ43_002911"
     CDS             complement(10650..11393)
                     /locus_tag="KRQ43_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH2743256.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYITDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            11561..12433
                     /locus_tag="KRQ43_002912"
     CDS             11561..12433
                     /locus_tag="KRQ43_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH2743257.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            12433..13098
                     /locus_tag="KRQ43_002913"
     CDS             12433..13098
                     /locus_tag="KRQ43_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH2743258.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            13119..13976
                     /locus_tag="KRQ43_002914"
     CDS             13119..13976
                     /locus_tag="KRQ43_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2743259.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGSYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(14132..16678)
                     /locus_tag="KRQ43_002915"
     CDS             complement(14132..16678)
                     /locus_tag="KRQ43_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH2743260.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYTSSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(16678..17364)
                     /locus_tag="KRQ43_002916"
     CDS             complement(16678..17364)
                     /locus_tag="KRQ43_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743261.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(17447..18436)
                     /locus_tag="KRQ43_002917"
     CDS             complement(17447..18436)
                     /locus_tag="KRQ43_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2743262.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIVCEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(18423..19109)
                     /locus_tag="KRQ43_002918"
     CDS             complement(18423..19109)
                     /locus_tag="KRQ43_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743263.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(19609..>19847)
                     /locus_tag="KRQ43_002919"
     CDS             complement(19609..>19847)
                     /locus_tag="KRQ43_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743264.1"
                     /translation="IEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRTAIEF
                     STEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
BASE COUNT         6736 a         3502 c         2448 g         7161 t
ORIGIN      
        1 tacacctatt tttaaatagg tataatttta acttatttgt aatttatctt gatctctaaa
       61 aacttgcaac tttacattag atgttaataa atctgagtaa ctataagata ctctaggata
      121 tccattactt tcatcatcta actttataac aaacacgctt ggataaactt tttctagtat
      181 accctctttt gtaataatct gctttcttcc tttattagct ttcaacaata ttttctttcc
      241 tatatgtctc tctaagctta ctcttatctt atctagagtt tgaacagtag ccacaatatc
      301 accttcttta acgtttatat gtttacataa tatcacatat aaacattttt gtcaaatgtt
      361 taaactaatt attttatata ttttttgcaa aaatgtcaat actatttttg aagatataca
      421 gtataattat gttaattttt gctaatgtaa tattgttttt ggcattgccc atctaaattt
      481 tcctcttgtt tcagaaccac caattccctt aacacctgta atagtctgct ctataacctc
      541 atcaatagga actactacat caattcttga acaagcaatt ttctccacta taaaaacagg
      601 gtctaatgca tgtatcatta ttcttccagg cgaacttgca taatttgctc ctgcacttat
      661 tattttttca taatttgatt ggcatgctcc tgcgaatatg acaagattat ccaaatttgg
      721 ttgccattta cgtgcttctt ttactgtttt aacaaaattt gaagagtttc tatagttact
      781 catatcttct atatctcctc tttttattgt cattgcatca tgacctgtta ttactagtat
      841 atccggatta tatttttcta gtagtgctct tacttcttta tactgatttt gctctgaaac
      901 agctacacct actgcaggta ttccaagttg agcatataca tccaagcaaa tttttaaata
      961 ttctttatct ccatctatct gtagtacttt tccaggcatt ccatatgtgt taggatttaa
     1021 ttgaagtttt ggaactgctc tagtcattct tttttgtctt tctttagctt ttcttactga
     1081 cttatataat aaattttcta catttttatc tattaatata tcttttatat caggtgcttt
     1141 tactaattct aggtcatcaa tataagcatc tgctattact ctaaatgcaa ttccctttag
     1201 tatagctatt ttctcattat tttcatctac accaaaagag actattttaa atactatatc
     1261 tttgttatgt gactttctag ctacaatgtc tcctaccttc atagttaaac ctccaataaa
     1321 tttttatctt agtttatact atgttcgata taaaactttg tttcctaatg tcaaaaaaac
     1381 atttcttata atacttcttt tatcactctt aaagcatttt tatagtatat cttttctata
     1441 tcatcttcac taaacccttc tttttttaga ggttcataca gtttacccat ctgagatata
     1501 tcttcaatct caacttttga atctattcca tcaaaatctg accctaggga tacaacatct
     1561 attcctccaa catttacaat atgttttatg tgtctaacca tatcttcaag tttactttca
     1621 cttttatcac ttaaaaataa gtggaagaag tttatacctg taactccacc tttatttgct
     1681 aatactttaa tcatatcatc agttaaattt ctagaatgat tcatcattgc tcttgaatta
     1741 gaatgtgtag caattattgg tttagaagaa atctttgcaa tttcataaaa tccaccatct
     1801 gaaatatgag aaacatcaac caacattccc aattcattca tcttatgtac cacttctctt
     1861 ccaaaatcag taagcccttt ttctctatat tctactttat tatgaggaaa gctcaattca
     1921 ttcacatgat tccaacttat tgtcatcatt ctaaccccta agtcgtaaaa tttctttaaa
     1981 ttttctaatt taccttcaag tactgcacct tcttcaatag ataaaagagc tgtaagttta
     2041 ccttctgatt ggtttttcat aatttcttca tagttagtag ctaaagctat ttcatcacta
     2101 ttttttttca tttcctcatg aaatttattt gccatactca tgcaataatc aaaaggatgt
     2161 tttacttctt cagtatcaac aaaaagagca aatgtttgag ctaatgaatc cccctttttc
     2221 aatctgtcta tatcaacaga atatttatta gacttaagtt cacttgtttc tacattttcc
     2281 attaattttg ctatagtatc acaatgtaaa tcaataaatt tcatatttat accccctgta
     2341 tattttatat ttatatctaa aaatagaaat agttgtcctt atagacaact attgacaact
     2401 attttttaat attcttttta atattactta atcttattct tcttttaagt taggtattac
     2461 ttttttaact tcttcaattt gatgccatgt tttatctata ttattttcac taatatattt
     2521 ttttaaatca gttaaagatg taaaatcttt aactgataaa ttgtcatcat catctgcaaa
     2581 tcttaaaata aacatgagac tcccttactt tccacaacat ttcttatatt tttttccgct
     2641 tccacatggg catgaatcat ttcttcctat ttttgcttct ttaactattg ttttagactt
     2701 cttataagcc tttattattt cttttctttg gtctgctggt agtatatctt cccaaccttg
     2761 taaattatat agccaatgag cctcaacagt taccatattg ttatataatt tttcccaatc
     2821 tatttttata gaaacttctt tatcagcttc tacttcttct aaaactatat cttcttttaa
     2881 gctttcactt attccatcta tgaatcccat gaaaaattca ttagtagttc caaatttttc
     2941 agccaattca cttactttac cttcaacaac atccatttta ttatttaata tttcattgta
     3001 tattccagct tcaactttca aatattcttc ccagaatttt acttctgctt cttgactttc
     3061 atgattatca cttaaatttc tccattcagt atataaactc atactttttc ctcctaagta
     3121 tacctatatt tttatagttt ttatagtata aaatctttta gttagattgg aagtttcttc
     3181 tttttgatta taccatattc tatttaaagt taactcttat attatatcat aattaaacaa
     3241 ttcttttaat acttttatag catactcttg gtttataaaa taagggcttg tcgcaattgt
     3301 tattactttg gcttttttaa ttaagttttt tatcttgtaa aatttgagtt caaatggtat
     3361 atagtccata tcacttgaaa atatatccaa atctatatca agaacaaact ctgattctac
     3421 ttctaaatca aatccataca gactatctat tattattaat tctgaaaata tgttatattt
     3481 taaagcaggt tttataaaac ttcccacatt taaaacttca tttgtatacc taaatacatc
     3541 ttttagatta tttacatcta catcatagtt ctcaggctct ctagtatcct tatgttggtc
     3601 tacatgcact aacttgcatc cttttgtaaa ttcacccttt aacaaagatt ttgcccaaaa
     3661 ataaaatgca tggttatgat tgtcaaacac atatatcttt ttatttccca ggacatattc
     3721 gaccatattc tccaatcctt ttgcttttat ttccttattt tcatctactt cattaaatac
     3781 cacctcattg cctaacctta catcatttaa tgtaccattt ataagttttg gaacgtatat
     3841 gctcttattt tctcttttat catatgaaaa tacattattt cctactggtt tttctatata
     3901 aaatccacta tattcataat tttccataaa actttatttc ctccattgtt atataaatat
     3961 ataagttata attttaaaaa ttaaaatgca cttattgtaa atcatattat ctattataga
     4021 aaacatctta tataactaaa tataatatct tctctcaata tgtattatac aataagtgca
     4081 aaatatattt atataaaata tactacattc ctataacaaa accatcagct tcaattggaa
     4141 ggtaactaac tcttctattc aactccacct ttccaaaaaa tactacccaa tatggtctaa
     4201 aaatactttc aattttaact atttcaatct ctgggattcc tcccataaac ctatgaatta
     4261 atctcatagc cattttattt gcctttgctt ttactcttcg ttcgtcctta ttactatact
     4321 gcacaatatt acaatccaca ttttttacaa tttcatatgt aggaaaatct tgtactatac
     4381 taccagaacc tgtagaacca ttcactaaaa tttttaattc atttatatca ttagaatatc
     4441 tcctattctt gaaaatggat ttcgttttgt gaattttaag tgtgataatt ttaaactcta
     4501 tataatgaag tctaacttca tgagcatatt tgttctttaa tattagctta ctaaataaag
     4561 aatttttccc acttttagct atctctatag cttcttcttt tgtaattctt ataggtaacg
     4621 ctcttatatc cataaaatca ttctctttct tatttttttc ttgtcatttt taaaactcta
     4681 tatatataat caaaaaatat tacaattaca actgccataa ctccatatgg aattattttt
     4741 ccaactataa tatcatttct agtcaatata ccataaaata taaatcctgt tattaaaaag
     4801 tacaataata ctagaaaacc gtctactcca agccatttta tttctaaatc tttttttacc
     4861 ttagacacta atttagacat agcagtttct ccttttatag attattttgt gtatttaaat
     4921 tttcacctat tctattacca atcatccatg caataaatga aaaaggtata gctatcacaa
     4981 gaggctctaa ctcaaagctc tgaactggaa atattttaaa ataaccaaaa gtcactccac
     5041 ctacaatcat tcctaaaata ccacccatag atgttcttct tccatttcca agaagcccac
     5101 ctactatagg tacaaatgcc gaacccatcc aaatacttcc tacaaatata catgcatcat
     5161 atacattttc aaatctaaat gctacgctaa gccccataac tgctgctaaa catacaccta
     5221 ttctagtaaa ctttactaat tgtttctgag ataactcttt ttttgtaatt cttccatata
     5281 tatcatttgc taatgtagct ccagctgcta gataatagct atccaatgtt gatattatag
     5341 aacctaaaat tcctattata aatattactc ttattccttg tggtaatgta tctaaaacta
     5401 aagttatata tccagcggct ggagccatct ctggataagt agctcttact ataagtcctg
     5461 ttatagttaa caccatgtca aaacatatcc atagtgaaaa acaagttaat aaggctcttc
     5521 ttccaacctt aggagaatct gctgctgaaa atctttgata aaaagttggg tctgaataag
     5581 ctccaaaaga atatacaatt aacatcaatg ctttcatagc tgacatacct tttgtagggt
     5641 gcataagctg tggtgcatct ttgagtgctt ctgtgagacc ttgaaatcct cctatttgtt
     5701 caaattgacc tggcataacc atagttaaac caaataccat acaaaaaaac aataccatat
     5761 ctgtaatggc aactcccata agcccaccaa gtactgtaag tacaacgact actcctacca
     5821 ttattaatcc tattaattct ttatctattt tccatgctac gttacctata gttcccatag
     5881 cagttatttc tccaagttgt gcacaatata taaacatcaa aattgcccca attatagcaa
     5941 catgcttacc ataaaaactt tccagtaaat caggaactgt tatattggtt cttatatgaa
     6001 tccttggacc aacccacaat gctaaaggca ttctcccaat atgtgcagct attgaccaaa
     6061 ctgcccatgc agatattcca tatatagccg catactctac actacctact gtaccaactc
     6121 ctccatacca tgatgcaacc aaagttccta ctattaagga ccatggtaaa cttcgatttc
     6181 ctaggtaata actttccata tcttttacat ttctagaaaa ataataacct attcctaata
     6241 atataaatgc aaatataact ataatcccat tttcccaaaa tgttaacata tctaatctcc
     6301 acattcttat attttaattt ttaactttaa tatctaaata tgaacaactc tacccatttc
     6361 cataaaaata ggtagagtta tataataatt ataagtattt aagtaatctt gttattaagc
     6421 aattttattg tttaaacctt tattttctct tttatttatt ttatttaaag cataagtagc
     6481 aaatatccct ataactgcac atactacaga taaaataaat atatatgtat atcctgtttg
     6541 tccatattta tctaaccaat tacctgcaat agtgtaataa aacgcatctg gagaaaatcc
     6601 tataaatgaa gcaaatccaa ctactgctcc tgtagtttct aaagatatat tagactctga
     6661 aacagatgca aagtatatac ctctaaatcc aaataaaatt acacttagta ttatcatgtt
     6721 tattacagct atccatataa atcctgtact cttaggaata accaagtaag cagctgtact
     6781 tactgtcatt aatataaatc ctacaaacat tactcttata gatgaaccaa ctttatctgt
     6841 tataacacca gcaactggag atgctcccat ttttataaca taagttctta ttattgataa
     6901 agcagaaact agagtcattg gcattacata aacttctgat aagtatggac ttaaataagt
     6961 taaacttgag aatactaaat aagttgaaaa tattataaga ccaattaacc aagcctttgg
     7021 cattgtaact acttttaaca atgacttaat acttaatcct tcatctgatg ctccactatc
     7081 ttttttctct tccactaaga aaaatagaag tataccacat attatagatg ctgcagaata
     7141 taaccatact acatatttga atcctactgt tatttcagca aatttaccaa agaagtaaag
     7201 acctataaaa gaaattaacg tacctgatac acctgataac ccttcataaa aaccaaatat
     7261 tcttccttgt tctgactcac ttccttgcat tctaacaacc ttaacagatg ctgagaagaa
     7321 agttaatatt gttgtaaatc cccataatac aaatattaag agtatcatac tatatgatgg
     7381 gaatgtagag aaataaaaac caagtactcc tgaagcaatt aaagaaaaag ttatcagctt
     7441 tctaaccgag aatctatctg caaaccatcc tcctataaaa taagatacca ttcctactaa
     7501 tccatataaa ctcaataagt tccctatttg tgtatggctc aatgataaag cttgttgcat
     7561 tgggtcataa aatgatgatt tcatatatgg taaactatac atagccgttg ttccaaatgc
     7621 caatatgaat attatcaaga atcttttaaa attacttttg ttctccatta attttctctc
     7681 cttaaaattt tattgtttat aatctcattc atgtaatttt attttaattt ttttattgct
     7741 tgtttaaagt catttattat atcatttgaa gattctaatc ctacagctat tcttattaga
     7801 ttttctccat tcatttgaac taatgtatgc tcttccccta agcttgttgc tattgttgca
     7861 agctctaaag agttcattaa ttttctacta gcttggtctc ttgtcaatcc attgatacca
     7921 tccttaagtt taaatgaaac tacacctcca cctaaaccat tcatttgagt tttacaaagc
     7981 tcatattgag gatgagattt taatgctgga tactttacca attccacatt ctcttcttcc
     8041 tctaaaaact ctgctactgc taatccattt tcacaatgct ttttcatcct catatctaac
     8101 gttttcatac ctcttaaaat catccatgca ctcattggtg gtaaagatgc tcctgtaaaa
     8161 caacataaac ttggccatct aactaaatct attaattctt ttgaacctgc tactgctccc
     8221 cctaaagtat ccccatgtcc atttataaac ttagtaagac tatgtattac taaatctgca
     8281 cctaaatcta ttggtctttg tacaattggt gtcccaaaag tactatcaac tatagctaag
     8341 cttttatttt catgagcaat ttctgctatt gtttttatat ctactaagtc taatgatgga
     8401 tttaaaggac tttctatata aactatttta gtatttggtc tcattgcttc ttttacattt
     8461 tgtggattta ctgcatctac aaatgtaact tcaactccaa atttagataa caactcagac
     8521 atgaataatt tagtgtgtga aaatattcca tctgaactaa ctatatggtc accacttttt
     8581 accaatgcta atatagtaga tgttattgcc cccatccctg atgtactaga tatggcactt
     8641 tctgcatttt caagcatagc caacttagct tctaactctg taagagtagg attacactct
     8701 cttgtataca catatcccca tgtcatacac aactcttcaa aatgctctac tgtctttgca
     8761 gcaaatgttg ctgtttgaca tattggtgta gccaatgcac ctgttgttgg gtctgcacta
     8821 tgtccccaat gtattatttt tgtctctaaa tcttgattaa tattgttact cattttgatt
     8881 tcctcccatt ttgacttatt tatacaacgt tttccctgcc aaatttaatc aatttagctt
     8941 agtcttaata cattttttca agtatacttt tttatttgtt ataatttcta aaaatatgac
     9001 acttattttg tttttttaca gttctaatta taaactctat agtaactata gagtcaatat
     9061 gtttttgata ttttttttac aatgtttaaa atagtcagta caaaaatagg tatatcttag
     9121 aataactaaa gtcatcctaa gatataccta tttttatatc acaatataaa taattacata
     9181 taagcattag tttttttatc ataaatagat ttttcaagat ttatcatctt ttcataaata
     9241 tattatagtt aaatatttta atattaccta acatctacaa taaaatatac tcttaaaata
     9301 aaattatata attaaaaata ctctataaaa gctaaaaagt tttctattcg ctacatctaa
     9361 aaataattag atagaggtat aaatgtattt agtttattta tacctctagt cttttataaa
     9421 ttatatctct actaaattga ttttttagca cgaataagtg tgctcttgga gataccagtc
     9481 atcttcacaa cctctctata tggcttagaa tttaataacc ccaatgcata ttgtatctgt
     9541 tgattgctgt atttctttgg cctaccatct ttaaagtcct ttttcttttt agcaaattct
     9601 tttcctaatt gagtacgttc tattatcata tttctctcaa gctctgcaac tgcaagtaat
     9661 gtagtcaaaa agaatttacc cattgaagta ttttctaaaa gacctatatt taaaatatga
     9721 acacttactt ctttagcaaa taaaccttct attagttgta tcccttctga tgtacttcta
     9781 gctagtctat ccagcttagt tgcaacaagt aagtctccct tttttagaga tgatataatt
     9841 ttttcaaatt taggcctgtt tgtagtagtg cctgtataag tttcctttat tattttagca
     9901 tcattatatt tattcaaaat ttcttgctgt tgctgataca aactgttgtt gtctgtttga
     9961 ttttttgtac ttacacggca atatccatat ataataatca tcacttccta acataaagat
    10021 tttgtacaga agttacccag aagcttgttt ttacttatct ttatccattt tactaaaacg
    10081 atttttgggt gtcaatactg ttaacttttg acaccataat aattccttta taatttgttt
    10141 gactatgtca aaaattacca atataatgaa attaatgagt ttatacaaat tggaggaaat
    10201 aatatgaata gtctgttaaa agaagcaata gatgaattaa aaaacatcca ttgcggggaa
    10261 gtttttttat taaaagaatt gttcaaaggc tatgaatgga acaggttgga gatgaatatt
    10321 agattgaaat taggaaaact ttttttgtat gaagtggtaa ctaatcccaa tttaaatgta
    10381 gaggtcatca ataaaaattc tgcttatcag caaatgtata aaaaaaaata gtgacttaaa
    10441 tgtatataat agtataatct tcttattgat tcaaaagtta aaacttttaa tacaaaacaa
    10501 tcattctatt ttaacattta tcaatatgtc taaatttata taattaacac atacgaatag
    10561 tattgtttaa atcacattat ttaagataga taaatcttaa ccctactcca gcataaatac
    10621 taaaataggg cttagaatta tctatatttt tatcccataa aatgcttagc tcttcctctt
    10681 gattgaacat atatatctgg ggaaatacaa tagaagcgta aatttataaa atttccaaag
    10741 tcagaaaact tcagttcaaa cttaggtata ccaaaacttt caggtgctat ttcatcaacg
    10801 ccaaaataga tgataattcc attatctgta atataaaatg cttggtcttc aggtataact
    10861 aactcaacat tagaataata catttctcta ttttcattta tttgagattt aatgtaatca
    10921 gtaattatat taatataatc aactccatct ctaaaaatgt cattaagtaa aagttctttt
    10981 ccagttgtca aatctatatt gtaattattc aatgtattgt atttaggccc atagttatta
    11041 gcaaacccca taaggtttaa tatcatactc agtacataat ttttattaaa agtaactgcg
    11101 taactggtag atacccaata gctttgtttt ggaagtgaat tttgagaagc tgcgttatta
    11161 tattctcgtt cttcttcctg taagccattt ttaaaattat ttacagtcat tcttacagca
    11221 ttgtttatgt tatttaaaat aactgggttt acatacgtgg attgatttct aatattgtat
    11281 ataacaggat actttacatc atatgaaaaa tacttacttc tttcaaaatc ttcattaaat
    11341 tgtacatata atatattata tgtacaggta tttgtagatt gataattttc cattaaaatc
    11401 ctcccccttt tataaaaaaa tcagatacaa tataatatgc ttaaaacagt aataatgtta
    11461 atagtaaatg taaagaatag aaagtatcta aaacagcaaa aaatgactaa ttttgtggta
    11521 taatacatag gattgagagt tattttatag gaggaaaaat atgttattat tagcagataa
    11581 atggaaagat tatgaactta tagatatggg aaatggagaa aaattagaac gttggggaag
    11641 ttatgtactt agaagaccag acccacaggt tgtatggcca atggaatctg aatgggcttt
    11701 atggaaaaac cctcatggac attatcacag aagcaataaa ggtggaggtc aatgggaaca
    11761 caaaaaaaga tatccagaac aatggactat aaattataaa aacttaaagt ttcacattaa
    11821 accaactggc tttaaacata ctggattatt cccagagcaa gcagctaact gggattggat
    11881 gatagagaaa ataaagaaag ctaacagacc tataaaagtg ttgaatcttt ttgcatatac
    11941 aggtggagct actgtagcat gtgcatctgc tggtgcagaa gtatgtcatg ttgatgctgc
    12001 aaaaggtatg gttaattggg caaaagaaaa tatagaatta tcaggtctta aaaatcaaac
    12061 agtaagattt atagtggatg atgttgtaaa gtttgttgaa agagaaataa gaagaggtaa
    12121 aaaatatgat gcaataataa tggaccctcc ttcttatgga agaggtccta aaggagaagt
    12181 atggcaaata gaagaaaagt tatacagttt tgtagattta tgtatgggag ttttatcaga
    12241 taacccttta tttttcttaa ttaattctta tacaacagga ttttctccaa tagttcttga
    12301 aaatgtattg tctacaacaa taggtaaaaa gacaaataca ggagatatat acggtgggga
    12361 attaggaata ccagcttcca gagatggtaa gatacttcct tgtggtatat ttggaagatg
    12421 ggagaaaaaa taatgataaa agtcatatat gaagataacc atttattagt tgtagaaaaa
    12481 ccagttaaca tattgtctca aggagataat actaatgata aagatatggt aaatctttta
    12541 aaagactata ttaaaaaaaa gtataacaaa cctggaaatg tatatattgg tttaatacat
    12601 agattggata gaccagtagg tggagttatg gtgtttgcaa aaacatcaaa agcagcatct
    12661 agattgtctg agcaggtaag aagtaagact ttcaaaaaaa cttatctagc tgttgttcat
    12721 ggcaagataa aatctaactc agatatacta aaagattttt tatataaaaa taaaaaaact
    12781 aatatggtaa ctgtagtgaa aaaaagccat aaagatgcca aagaagctga acttaactat
    12841 aatgtattag attttaaaga aaatctaagt ttagttcaag ttaatttaaa gactggtcgt
    12901 tctcatcaaa taagagttca atttgcaagc agaaaacatc cattatacgg agaccaaaga
    12961 tatggcaaag aaataaataa gattggacaa caaatatctc tttggtccaa taagatagaa
    13021 atttgccatc ctactacaaa agaaaaaatg gaatttacat gtcatccacc tgacaaatat
    13081 ccatggaata tattttaaat ctcaaatgag gtgattatat gagtaaaaaa ttttcaatag
    13141 gagaaatgtc taaacttcat aaaataagca tacagacact aaggtactat gaccaaatag
    13201 atttatttaa acctgttcat gttgaccaag aaagcaatta cagatattac tcaattgacc
    13261 aattttcaca attagatatt ataaaatatt taaaatattt aggtatgcct ttaaaagaaa
    13321 ttaagtcaaa gcttgatgaa aataatgaag aaattctaaa attactaaca aataaaatta
    13381 atatagtgga tgaaaaaatt aaagaattag agcttataaa gaaggtacta agcacaaaga
    13441 aagaaactat ggaaaaaggt atgaaagtag atgaagttgg taaaatagtg agaaaacata
    13501 ttccacgaag aagtatctta tctatagagt atgaagaagg attaagtagt gaagaaacta
    13561 tggaactttc cagaagacaa atagcaaata tattagaaga taatatatct gtgttctatg
    13621 gtggagtaag tggacttgta tctatagata aatttttaaa agaagataaa gttatttatg
    13681 acaatagttt tgttactgtt gaaagagact tatttgatat aaaatcacaa aaacatataa
    13741 cagaaatttc atctggtgat tttatttgta tgacatataa agggtcttac aaagaaaatt
    13801 ataccgcttt taagaaactg gttgattatg ttgaatataa aagaatacct attgaaaatt
    13861 atatatatga aatacctata atagaccctc tgtctacaaa caacgaagag gaacttctaa
    13921 cagaaattca aatacaagtt aaaaagagag aaattgactt aagatgtcta gtgtagtaat
    13981 ctagtttact tacacatctt aatatagttg tctattatca acatatgatt tttctagata
    14041 gtgattccta acagtgagat tttcaaaaaa taggaggaaa tatggctaat gctaattccc
    14101 tcctattttt aattaatcca tatcatttta attaagccat gtcatcacga agtgcatcaa
    14161 taatattttc tttttttatc ttattaatag tatacaacat tgtaataaat actataaata
    14221 aaacactaaa tatactaatt ccaatactaa accatggaat cacaaaatca atatcatctg
    14281 taaccattac tttatgaatt agccatgaag aaattactgc tataggaagt ccaaagaaca
    14341 atgctctcat gccataaaaa gcacactcaa aattcatcat cttttggaaa tcatgctcag
    14401 acattcctac agagcgaagc atggcaagtt ctctacgacg taacttaata ttagttgaaa
    14461 ttgtattaaa cacattggca atcgaaatca gagaaatcat aattatgaaa gtataggcaa
    14521 aaacattggc aataaaaatg taattacggt tctcatccat cattccatac atattgtaca
    14581 gattgtactc attagtaact ccctcactct caataatttg ctccatttct gcaactgact
    14641 gagtaggatt tttcgattga aagcttaaac tttcaattcc tgtagaaaca ccaggaatct
    14701 caaacttatc tttggctgaa taaggagcca atactctgaa gcttgctttc ttcacatctg
    14761 aacttctgat tcctggagga gaatcaggtg gcactacttt gacaaatgaa atattcacat
    14821 tttgtctctc aggtatctcc aacttgccat tagtttcagg agtgagacta acattcatag
    14881 aagaactgtt gaaaatatca ataatattat tatcctttgt taccatagaa acagcaatca
    14941 gttttgcatt ttgtccagta tattcttctg ctggtaatcc aagactttta ataatattca
    15001 gataagttct atcatcaaga aattgcatat ctactggtaa ttcaagcatt tcactcatag
    15061 aatgtgaacc ctcatagttc aaataatcgt ctgtaagctc acttactttg gcaacacatg
    15121 aataggtcat aagtttctga tacaaacctt cgtaaacacc atttgcagtt tttagcttat
    15181 cgtaaagctt caacatttcg ttgtctttca taccttgtgt agaaaaaata atatcctgat
    15241 cagtaacctc tgacctctga tttgacatct gttttaggtc tgctactaaa gcacttgtag
    15301 atataaataa aactatgctt aaaacaagcg acaatacaat acttcgataa cgtttcttgt
    15361 ttcttttaaa gtttttcata gcaagaactc cctcaagacc ataaactcgc tgtgttagtt
    15421 ttgatgtctt cacagattta gattcaattt ttacctcatt tgtctgacga atacactcca
    15481 tcactggtgt gttggcagcc tttcttgctg gtatgtaagc agaaattaag attgtaacca
    15541 tacttaccac tgctgcaacg atgattgcag ggatagacaa tgttaatgtc aacggaacgt
    15601 ttacatagag aatatttgca aagtttttag ctatgacaga aatcacaagt ccaatactga
    15661 ctataccgat tgcaacacca attggtatac caatcgcacc aatgcaaatt ccttcaaata
    15721 gcaccgaatt tcgtaactgt tttgctgtag ctccaacaga tgaaagtatt ccaaattgat
    15781 gtgttcgctc gttcaatgac atgttaaatg aattatatat tagaaaaatt gagcctagca
    15841 tgattatggc aagcacaatg ccaccaaccg agtacaaaaa catattgaac aaattgttat
    15901 cagaaacacc tatgaagcgc aacacattgt cattgaaaat ggaagcatgg tctttagtgc
    15961 tacttgtgta agagcgaatc tgatgtggat ttttcaatgt gacaaaaagg ctaagactgt
    16021 cagtcttgac ttgtttatct tctttggtta tcaaggtata tcctggtgca gaagattctt
    16081 caaatacggg ctttctacag atacccacaa ctgtataagt tttcttatcc tgtggcacaa
    16141 aaacttcact cccagcagtg taggggtcac tctgaccaag cttttcattt tcactcattc
    16201 gtttccctac atccaaagaa atagtatcac ctactgcaaa tttgacacca ccatctgtcg
    16261 caactttact tgaaacaaga atctctctac tattttcagg taatcttcca gaaattaaag
    16321 ttataggcaa agtatcaaaa gcttctttgc taaatccagc aataaaaaga tatggtttat
    16381 ctggatttct gttaccttca agtgttgcat agccaatatt ttcaaatgtt gcagtatttg
    16441 caacttcatc attgactctt tgttcctgta caaaagaaga atccacatcc aaaaactgga
    16501 catgccaatc accatatttt ataatagctc catttgtcat atagttcatc aaagaaactc
    16561 caaaggtagt aactgctgta atcatagcag ctgacagaac aactcctata attgttacaa
    16621 gagttcgagt gcgattcttt ttcaatcctt gcagagcaac tttgttaaaa atgttcatta
    16681 acgattcacc ttcctctcat cacgcaccac ttttccatct gaaatacaga taattctatc
    16741 tgcctgtaaa gcaatgtttt catcatgtgt gacaataatg agagtttggt gatatttact
    16801 atggctctct ttcagtaact ggataatctc ttgtccattt ttactgtcta agctacctgt
    16861 aggctcatca gcaagcataa ctgctggtgc attcatcaat gcacgaccaa tggcaacacg
    16921 ttgctgttgg cccccagaaa gttgatttgg taaatgtgtt tttcgttctt ttaaaccaag
    16981 taattctaac aagtcattta accgttcttg attgacctta cgcttatcca taagtatagg
    17041 caatgtgata ttttccacta catttaatgt gggtatcaga ttgtgaaact gataaatcaa
    17101 tccaacttgt cgcctacgaa aaatagcaag tttttcattg ctttggccat atacatcttg
    17161 cccctccaga tatatctttc cacttgttgg tacgtctact cctgcaatgg aatgtagtag
    17221 tgtagattta ccagaaccag aagaaccaat gattgcagta aactcccctt tttcaatagt
    17281 aagtgagaca tggtcaagtg cagtaacctt attttcattc ttaccataaa ccttacataa
    17341 atcttcaatc tttaaaaacg ccattatata agtctccttt catattttat aaatatatca
    17401 tagaactttc aacttacatt taagtgacat ttaaatgaga gattcgtcac tttggaaaac
    17461 gaataacaaa tattgcacca ccttgtgggt gattttgtgc agtaattgtt cctccttgtc
    17521 tcataataat cgtcttacaa agtgccaatc ctattccata accagctgtg cttgaatttt
    17581 tcccacgata aaatctgtta aatagacatg gtaagtcttc ttttttaaag cctgctccgt
    17641 tgtcatgaat agtaagttga gtaaacaaaa agttgtcctc acaaacgata tcaatttttc
    17701 cattatcacc cacactctcc atgcagtttt taaatatatt ttgaattgct tctgaaagcc
    17761 aatttaaatc acccaaaatc cttactcctt ttggtatatc aatatgtaaa gtgatattgt
    17821 gcagttccat gggaatcaaa agttgatgaa gtgcagaact aatcaaatta ttcacatcaa
    17881 tttgttcttt ttgaaagact acaatacctg catctaaacg tgataatttt aaaagggaag
    17941 taatcagcca gtccattcgt ataagtaatt cctctgtttc tcgtatcaac tcttttctct
    18001 catcttcatc agaagtattc tctaacagtg acaaaataag agttactgat gtaagaggag
    18061 tgcgaagctg gtgggctatg tcagctagtg agtcagcaag gtgttctttt tcttttttca
    18121 gtgcgtaatt ttgctctcta atacgtaacg tcattttagt tatttcactt tgtagaatag
    18181 aaagctcacc ctcatctgat tcagcaatat acagatggtt agcattatga agcacaagat
    18241 taatttgttc tgaaatctgt gcaatacttt tgtatcgatt tttagtaaac acaaaaaatg
    18301 ctattccaaa ggtagtggca gaaacaatag aaagtattcc agtcataata ctgattgcaa
    18361 atcccagggc tacagtgaga atagtaatta ataagaataa aatagcaaat tttcgaaact
    18421 ctctatttcg aaacataact tccccccaat ctataccctg tcccacgaac agtcaaaatt
    18481 atttgtggac ttgaagggtc atcttctatc ttctctcgca agcgtttgat gtacacagtc
    18541 aatgtgttgt cattaacaaa ctcacctgcc gcatcccaca attcatcaag taatcttacc
    18601 ctcgtaataa tacttttagg attgctaata aacaccaata acaaacggta ttctaaagct
    18661 gaaagaaaaa cctcattgcc attctttttc acaacaccgg ttgccgtatc tacataaagc
    18721 ccacaaattt caaaagttga cccaaaacgc ccactttttc gtagtgctgt tctaattcgc
    18781 gcaatcagtt cacgtggacg aaaaggttta gtaatatagt catctgcacc catattcagt
    18841 ccagtaacaa cacttgattc atcaccagaa gccgtcaaaa agataacagg aatgtcttgc
    18901 ttttctttga tttctgtgca aatcgtaaac ccatttccat caggtaaaga aatatcaata
    18961 agtgccaaat caaatttatt cttagcaatc tctacaagtg cttcacttct tgtggataca
    19021 tgggttacta taaatccttc tgaattaagc aaaagaataa gatttttggc aattgcttta
    19081 tcatcctcaa ctaaaaatat ccgtttcatt tactttcatc ctcctttatt ttattagttt
    19141 tatatattcc agcagagcaa tagtacacta ctattttact tatcattaca caattttcag
    19201 tagtttcttt tgttcttata taatccatgc ataatacctc cattgattta ttatatttct
    19261 tataacataa atacacaaga taagacaaaa aacataatgt aagtgcaagt tttttaactc
    19321 actaacttat aaacatacac tcctactaac actactttct tgatgacaca tcttacaagc
    19381 ttatattcat acatcaatga aaaattaaat ttatccattt attaaaataa aaggcaatag
    19441 cttctatagc taatgccctt tatcttaaaa tgatttaaat actatacaat ttttataaat
    19501 ggctataaat aaactcgtat agaatataaa atttatctac agtcttttgt tatacaaaat
    19561 ttataacctc ttatagaaca aatttaccac tttgtaaact tatcactttt actcagctat
    19621 attataaact tttaatttat ctttgtttaa atgtttcttc ttaacttcta ctaaagcttt
    19681 tagcgtatcc aaagatgtca ttatttcagt agaaaattca atggctgttc ttctcatctt
    19741 aaatccatct cttgtagagt catttccttt agttggtgta tttattacta tatcaacttg
    19801 tttatttctt atagcatcta atatgtttgg tctaggctct tcaattc
//
LOCUS       DAEQJM010000065        19775 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.065, whole genome shotgun sequence.
ACCESSION   DAEQJM010000065 DAEQJM010000000
VERSION     DAEQJM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19775
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.065"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..259)
                     /locus_tag="KRQ43_002920"
     CDS             complement(<1..259)
                     /locus_tag="KRQ43_002920"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBH2743265.1"
                     /translation="MVFETFDKVIKLHPNAKPVFHSDRGFQYTSKVFESKLLAQGMIQ
                     SMSRAGRCIDNAPMEGIWGILKVEMYYLRKFDTYEQLVKIIE"
     gene            355..848
                     /locus_tag="KRQ43_002921"
                     /pseudo
     CDS             355..848
                     /locus_tag="KRQ43_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            1390..2745
                     /locus_tag="KRQ43_002922"
     CDS             1390..2745
                     /locus_tag="KRQ43_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2743266.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATVLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(2863..3531)
                     /locus_tag="KRQ43_002923"
     CDS             complement(2863..3531)
                     /locus_tag="KRQ43_002923"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HBH2743267.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(3598..4026)
                     /locus_tag="KRQ43_002924"
     CDS             complement(3598..4026)
                     /locus_tag="KRQ43_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH2743268.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            4133..4726
                     /locus_tag="KRQ43_002925"
     CDS             4133..4726
                     /locus_tag="KRQ43_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBH2743269.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENATKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            4846..5781
                     /locus_tag="KRQ43_002926"
     CDS             4846..5781
                     /locus_tag="KRQ43_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBH2743270.1"
                     /translation="MDKFKYAFDDKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(6052..6996)
                     /locus_tag="KRQ43_002927"
     CDS             complement(6052..6996)
                     /locus_tag="KRQ43_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH2743271.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKVCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            7312..8742
                     /locus_tag="KRQ43_002928"
     CDS             7312..8742
                     /locus_tag="KRQ43_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2743272.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNADLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            8942..9526
                     /locus_tag="KRQ43_002929"
     CDS             8942..9526
                     /locus_tag="KRQ43_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HBH2743273.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(9630..10409)
                     /locus_tag="KRQ43_002930"
     CDS             complement(9630..10409)
                     /locus_tag="KRQ43_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH2743274.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(10479..11735)
                     /locus_tag="KRQ43_002931"
     CDS             complement(10479..11735)
                     /locus_tag="KRQ43_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBH2743275.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            11993..12892
                     /locus_tag="KRQ43_002932"
     CDS             11993..12892
                     /locus_tag="KRQ43_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBH2743276.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            12916..14364
                     /gene="ddlR"
                     /locus_tag="KRQ43_002933"
     CDS             12916..14364
                     /gene="ddlR"
                     /locus_tag="KRQ43_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HBH2743277.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            14423..15229
                     /locus_tag="KRQ43_002934"
     CDS             14423..15229
                     /locus_tag="KRQ43_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH2743278.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKISTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            15255..17174
                     /locus_tag="KRQ43_002935"
     CDS             15255..17174
                     /locus_tag="KRQ43_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH2743279.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVKRGAQ
                     ARSTKQKARLQRFDELMNRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(17416..17763)
                     /locus_tag="KRQ43_002936"
     CDS             complement(17416..17763)
                     /locus_tag="KRQ43_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HBH2743280.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(17750..19678)
                     /locus_tag="KRQ43_002937"
     CDS             complement(17750..19678)
                     /locus_tag="KRQ43_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HBH2743281.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTTLPIVLSKVKNNEQE"
BASE COUNT         7342 a         2890 c         2617 g         6926 t
ORIGIN      
        1 tctctattat tttaactaat tgttcatatg tatcaaattt ccttaaatag tacatttcca
       61 cctttaaaat tccccaaatt ccttccatag gagcattgtc aatacaacga ccagctcttg
      121 acatactttg tatcatacct tgtgctaaaa gtttcgattc aaacacctta ctagtatact
      181 gaaaacctct atcactatga aaaacaggtt ttgcatttgg atgtagtttt attactttat
      241 caaaagtttc gaataccaag ttattattat tcgattttcc aataacatat gaaattaata
      301 gatataacgc cttctatttt acagtcttat ataaataaca tatacaatga gcacatgtta
      361 aattcaataa aaaaccaagt cgattttata aaatcagtat tgaaagaatc ttatagatta
      421 aaagaaatat cagaaaatat ttgtgatttt gttacaaccc caatcaaaaa aaatagttca
      481 acttctaagt tttatacaaa gcaagaaact caattattat tagaaaaatc aaaaaatatt
      541 cctataggta taccaatttt tttgatacta actcttggat tacgttttgg tgaagctgta
      601 tcacttatat ggtcagatgt agaccttgat aaaaaatctc acatgtaaat caaacattag
      661 tttatgtata caataaaata atcttcaaag accctaaaat ccctagatcc aaaagaaaat
      721 tatttgctcc tgatgaactt ataagtttgc ttaaagggca aaaattaaaa caaaataagt
      781 taaaattaca gggtatattg aaaaatgaat ttgatttgat atgcttaaat aaaagattca
      841 acccgtgagt tcaaccaact tttgttgttc attttaaaaa actattaaga gataataatc
      901 ctagagatat aaaagtacat gaattaatac atgcaaatgc gactttgata ttactttcag
      961 gtactaacat aaaagctatt tataaaatat tagtacatgc agatataaaa atagctatga
     1021 ataaatattc gatattctca cttattagat gaaatggata aagaaacatc tgaaaatata
     1081 agcaaaatac tattcaaata atgttcagtt ttatgtcaat taaatgtcac tcaaagtgct
     1141 ttttttccat ttgtcagtta aatgtcactt aaagtacctt tttcctattt gtcagttaaa
     1201 tgtcagtaat atataaataa gatatattta taagaccctt aaaatcacta ttatttaata
     1261 aaatttataa ttatatacta tttgctgttg acattggtat tataccatag tttatcattt
     1321 atattagaaa taaaattatt aattaatagt ttcgtaattt tataatagat ttacagggag
     1381 tgataataaa tggatacaaa aatatctata aacgaaaaca tgagtctagg taaaagattt
     1441 tttaaatacc tagcaccatc tgtagttgca atgtgggttt tctcactata tacaatggtt
     1501 gatggaatat ttgtaagtaa aggagttgga gaattggctt tagctgctgt caatatatca
     1561 atgcctttta ttaattttat atttgcagtt tctctattat tttcaactgg tgcatctacc
     1621 ataattgcaa tctatctggg gaaaaaagat attaaatctg ctaacgaagt cttttcattt
     1681 aacttagtat caataattat attatcaata attatattag ctataacttt ttttaattta
     1741 gatagattag cactattttt aggagctaca gaatctacaa ttggtatggt taaagattat
     1801 ttaggaataa taatattttt taacggattc tttatagtgt cttattcttt agaagttata
     1861 ataaaaactg atggctttcc aatattagct actgttggtg taataatatc tgctcttaca
     1921 aacatcatac ttgattactt gtttgtaatt gaatttggat ggggtgtaaa aggtgctggt
     1981 attgcaactg ttttgtctca agtcttttct actattttct tcttaataca ttttttaaga
     2041 aaaaactcta ctttgaattt ttcaaaattt agaattgatt ttaagacact tagaaaaatt
     2101 gtatttatag gttttcctga ttcaactact gaattaagtt gtggtatagt tgttttactt
     2161 tttaacttaa gtcttactaa atatattgga gaaaatgctc ttatttatta tagtgtcata
     2221 aattatataa atacattagt acttatgact atgatgggta taactcaagg tatgcaacca
     2281 cttactagct tttattatgg tgcaggaaat atagataatg taaaaaaatt attaaaaatg
     2341 gggataaaag ccacaataat agcatcagtt gctgtatttg caatttgtat ggctttttca
     2401 ggaccaatag tctctttatt tatacaccca gaagaaacaa tgctattcaa tgaaggagtt
     2461 cgtgtattta aaatattctc tatatctttc ttattggtag gaattaatgt aataatttct
     2521 ggattctttg tatcagtaga aaaaccatca atttctactg ttatatctct tggtagaggg
     2581 cttgtaatag ttgttttaag tctaatttca atgatactaa tatttggtgg acaaggaata
     2641 tggatgacta ctattgtttc tgagtttata tgtcttattt tatcattagt ttttctaaaa
     2701 aagaattttt ctacattaga ctctaatcta aataaggttg cttagatgat aagagtagca
     2761 atatatgaaa atatctaaat aaaaaatacc tattatacaa tcttgcaaat attagacctt
     2821 tgcaaaaatt aggattatat aataggtatt ttatttatgt aattatttta tttctaaata
     2881 tccatagcca tcttttatta aagttccttt tacttcatat tctacaggtt ttttaaatat
     2941 tggaccatct acgacaaatg tatgatactc tccatgttct ccacatgggt ctgcaccagc
     3001 attttttatc ttctccacaa gttctctagt taattttttt cctaaaaatt cctctcctaa
     3061 gtgctttaag tttacttttg ttacaacact acaaaatcca ctgtctataa attcatatac
     3121 taaatcctct ctactctctt gccataatgg taaatctact ttcataccaa ctgcttcaca
     3181 tctatcagta tcccattttc tatgactttc tatatctata tctccatatg cacatatcgt
     3241 tgctcccatg tttttagctt ttattaaagc cctctcaaag ctctcttcat atccttctac
     3301 accacactca gcaactaata aaggtaatcc tatattgcta cttacttgct taagcatatt
     3361 atattctaaa ttatgtgtcc atgactttcc atgttcttca cttatagttg tcaagagtgc
     3421 cacaggctta tatccttttt tcaacattcg atttaatgct aatatactat ccttaccacc
     3481 actaaatgac attacaaatt tttcatcagc caattttaac acctctttca tctaactttg
     3541 ttttattaac ataattatac caaatttttg agttgcatag caaattatat taaattgtta
     3601 attcactata aagaatgtcc ctaatattaa aagtataacc cctatgtatt tgtataaatg
     3661 cattgtttct tgtcccaaaa ttacgctatc aataaaaaat ccaactaaaa cttgggatac
     3721 aagtgttaat ataagtgtat ttgatactcc taaatttgga attgccttta ctgtaaaata
     3781 tattattaaa cctccaaata ctcctcctaa taacaactta taattaaaac catttataga
     3841 tactagacac tttaagtcac ctgtaactat tatacttgcc aaaaaaaata ttgctcctac
     3901 agttaaactt ataaaggtgg ccactaatgc tgttgtactt tttcctagtt ctccatttat
     3961 aaaagcttca agagctgtag aaccacctgc taataatgca aatattattg cccataattt
     4021 tgtcatggac aaacctcctt ctatataatt ctattaatag aagtctatga tacaacctat
     4081 taattaatta ctaagtatag tttaattttt atacactagg ctttatttgg atatgaattt
     4141 ctgttataat tgttctatcg attttggagg tgattttatg tacacaaatt ttaatatcga
     4201 ttttaataac tttaataaaa aagaaaatgc tactaaattt atgttaatgg gagtattgct
     4261 cattatctta ggattattat gccttacatt taagacatta ggtataaaat taatttcttg
     4321 gacttttggt attgcacttt tattctttgc atatttaaat ttaaaaaata ttaatgaact
     4381 aaaaagatat gctactaaag aagaaattaa accctctatt aatatccaat gggttctaat
     4441 aattgcatgt atattacttt ttgtatttcc tcaaaaaata caaagcatat tttcattatt
     4501 tttagggttt tatttaatct ttaatcaact agtagcactt gtaaatagta agaataatcc
     4561 ttattctaaa tttacaactt ggaatatagt taagattcta tttggtatat gccttatatt
     4621 atctccactt tttttatcta gatttatagt atcgataatg tcttttttca taatattatt
     4681 tggactagtt ctatttttct ctggaaatac agcgagaaaa tattaattat tttctcgctg
     4741 tatttttata ttacttaaaa tagaatttgt ttaagttatc tatttgtggt aatatgtttt
     4801 ttgtacaagc tcagcgtaca attttattag aaataggtga tttttttgga taaatttaaa
     4861 tatgcttttg atgataaaag atatcatact tggaattact atcttagaaa tacttttgga
     4921 gaaaaagttt ttaaggtatc tataaatgca ggatttacct gcccaaacat tgatggaagt
     4981 cttggttatg gcggatgtac ctactgtagc aaagaaggct caggtgattt tgctggaaac
     5041 cctaaagata atcttatcag tcaattttat aatataaaag aaatgatgtt aaaaaaatgg
     5101 cctcatgcaa agtatattgg ctactttcaa gcctatacaa atacgtatgc tcctcttgaa
     5161 gttttaaaag aaaaatatga gactatatta gaacttgaag atgtcatagg tctttcaata
     5221 tccacaagac ctgactgttt gccagatgat gttgtagaat acttatctga actaaataaa
     5281 agaaccaatt tatgggttga acttggactt caaacaattc atgattctac atctaaaatt
     5341 ataaatagag gtcatgatta taaaacattt gttgaaggtg ttgaaaaatt aaagtctaaa
     5401 aatataaagg ttgtcgtaca cattataaat ggtcttcctg gtgaagatta taatatgatg
     5461 atggaaacag caaaggcagt tggtaaaatg ggtgtagacg gtataaaaat ccatctattg
     5521 catgttataa aagatactcc tatggaaaag atgttacaaa atggtatgtt aactcttatg
     5581 gaacaagatg aatatatcaa tcttgtctgt gaccaattag aaatacttcc tgaaactatg
     5641 ataatccata gactcactgg tgatggtaag agggatgaac tagtaggtcc tatatggagc
     5701 ctaaaaaaat gggaaatttt aaatcaaatt gatgatactt taaaggctag aaattcttat
     5761 cagggctgta agtttgttta atacaaaata ataactatag aaatggttat ataaatatag
     5821 tcctttctat agttatttag tatttacaaa acaaaatatt aatttgtaca tttatacaat
     5881 atataataaa aaatagatag tctaaactgt atctacttat attttatttg tactgtccac
     5941 tttattctat aaaatttata aatagttatt ttttaatacc aaatataatt tggtataatt
     6001 tttgttggat tctaaaatgt ataccaataa atccttttta agtatataat tctaaatact
     6061 ttcagttttt tcaatctgct ttaacttgtt ggatttataa aatattctta tttcatcata
     6121 agaaagatta agtgctacta ctgcagatat taacatcaac atcactccaa ataacttccc
     6181 taaggaaaaa ctttctccta atatagtgca accaattatt actgaaccaa ctaactctac
     6241 tgatgccaca acacctgcaa ctgacaactc tacaccttta gatatacctg ctgcataaaa
     6301 aatatatgca agtgcagctg gaacaatgcc taacattagc atacaagata aaacatctaa
     6361 atccttagca taatttaaga tttcccaagg tctcgaagaa ggaatcataa atatagctcc
     6421 aaataagaaa ctgtatacta atattgttga acttgaaaat tcctttaaag catttttact
     6481 aatagttggc ataagtgcat atgctattgc tgataatacc ccaagtaaaa gtccaaaagc
     6541 gtttaaacct tgaaaatcca aacgtccacc agtcactgcc ataattgcac caataaaaca
     6601 aagaataagt gaaaataatt tgcttctagt aatattttct ttataacata cttttgaaaa
     6661 tattgctaaa aacagtggtg atgtatatag taaaactgct gcaattgata cacctgcaat
     6721 gtcaattgct ttaaaataac ataaattaaa cattgcctga catataattc ctattattac
     6781 tgaatatata attccttttt tgcttatctt taagatttgt ggtgtcctta tagatgaata
     6841 tacgcctaaa actataaatc caaaaaacaa tcttgtaaat gctacttgtt ctgatgtcag
     6901 tccatttccc attaaaaact ttccaaataa tccaagtgta gcccataata accctgctat
     6961 tgctataaat acataccctt tacttttttc tcccatttta aattcccttc tatttttatt
     7021 tagtcaattt acactcttct ttttaagcaa aaattatgcc atcttaaacc aatatatatc
     7081 gactctaaaa ccctagtctt tccaataata ctaataagtt ttcaattttc ttatatttat
     7141 ttttcgctta ctttaagttg atttagactt attttaattg taaaatgagt tatatataac
     7201 ttatttaaag ttaaaataga ctgaaactta tataaatatc aaattttaag tatattaatc
     7261 aattaaacct attttaatat atcattaaaa atttaggagg aaaatataaa aatgaattta
     7321 gatttggaat tttatcaaaa aatattagaa gcttcccatg atgaaatatg tgtttctgat
     7381 gataaaggaa taataatata ttgtaataaa gcatttgaag aaaattatgg tctaaaaaaa
     7441 gaagatattt taggaaaaaa tgtttctttt ttagaagact ctggatattc aacaaaaagc
     7501 cccataccaa ttgtattaaa aacaaagact aaattttcac tggaacaaga tactcaaaca
     7561 gggaaaaagc ttatcataac tgctacccct atatttgatg aaaatggaaa cttagaattt
     7621 actgttgaaa attgtagaga tataactgaa cttaataata taaaaaataa acttgaagac
     7681 acaaaaaagc aagtaaaaaa atataaatct gaggtagaaa cactatacag aactgcactt
     7741 agaattgaag atactgtaat tatggacgga atagtgatga gaccaatcat aaacacagta
     7801 aatcatgttt ctaaaacgga tgtaagtgta cttttattgg gtgaatctgg aacaggaaaa
     7861 agctcacttg ctagatatat acaccacaac agcaatagat ctaatggccc atttataaca
     7921 ataaattgtg caactatatc tccacaactt cttgaatctg aactttttgg atatacttca
     7981 ggtgctttta caggtgcaag tactaaaggt aaagttgggc tcgtagaatt agctaatgga
     8041 ggaactcttt ttttagatga aataggagat ataccacaaa atctacaggc aaaatttttg
     8101 caattaatac aggatagaac ttttactcca gttgggagct taaaaaataa aaaggttgat
     8161 ataagaatta tatctgctac aaatgctgat ttagtttcaa aagtaaaaga aaaaaagttt
     8221 agagaagatt tatactatag attaaatgtt atagaaataa aattgcctcc tcttagagaa
     8281 agaagggata atctagtgga aattataaaa tattatttta ataggtactc aagtgacttc
     8341 aacctaaata aaactatttc taaagaagct atggatgcta ttgcaaatta tagattccca
     8401 ggcaatataa gagaattaca aaatataatt caaaaaatct tgcttacttg tacagataat
     8461 catataacaa tagatgactt accaaacatt cttacaaaaa atatacatat taccaataat
     8521 ggaaataaaa cacatatatc ccaaattaat aaggttatta tatctgactc aaaatctact
     8581 aattataaaa ataaaaattt tgacacctta attaaagagt atgaaaaaaa tataattttg
     8641 gatgcttatg aaaaatttgg tagttcttat aaagtagcca aacaccttga aatctcacag
     8701 tctaaagcca ataggttaat tagaaagtat actaatactt aattttaaat ttgataaata
     8761 aaaacttaac actatttaca tattgtaaat ttggccattt actgttatta tgaatatggt
     8821 tgaaattatt taaataaata ctgttgactt agtttcatat atttaccatt aaacttttat
     8881 cataaatatc atatcataat aatatattta ataagtctaa taaactatac gaggtgtaaa
     8941 tatgttaatg aatacccatt ttattatggc aaaatcaata cttgataata tagatgaaaa
     9001 taaaacattc tttataagcg aaaaaaattt tatatatggc aatataaagc ctgatgcttt
     9061 ttctaaatat aaattaaaaa aacattattt agatgagtca tttaatatga ttgtttctaa
     9121 aataaactat ctatgcagtc ttaatataga tagtctttct aaatactttt cagtaagtag
     9181 acttagtcag gaactaggag tcatatgtca ttttttatgt gattttttct gtgtagctca
     9241 cagtgaacgt tgggaattta agcatagctt aaataaacat gttacttatg aaagagaact
     9301 tggagcattt gcaaaagatg ttgatttatc taaaattaaa tgtggtacta taaatagtag
     9361 ttttgagaag ttttttacta aactttatag tgattacaaa aagaaaactg attatatgaa
     9421 tgatttaaaa ttttcagctt atacttgtaa tagtgtcata aattatatac ttgactctat
     9481 tttatctaat acaataaaat catatcatat agcaaattgc ggttaactta agaattttta
     9541 aatttatata aacttataat tgaatataat taaaatgact gctctataga atataatttt
     9601 atacttctct aggacagtca ttttttatac taactattta tctccattat aacatctatg
     9661 gcacttttta cactatctac tacataattt gcactttgct ttacatcttc ccttgcctta
     9721 gacattgcaa aactatattt aaatccttct aacatgcaaa tatcatttgg agaatcccca
     9781 atagtagcaa cttcatctgg acttacattt aacgttttta ttacatgctc tatacttcct
     9841 ctttttgaca cacttttagg aactatattt aaagtatatg ttccagaaaa atatatttct
     9901 aatacttcac taaactcact ttttagataa agttctattc tggataactc ttccaaattt
     9961 tcagaacata cgcctatatt tcctataaga ttatcaaaac tacttctttt ttcaaaatct
    10021 gggtcaacta taaagtcact agaataatgt ctaaaagcag tggtatcact acccacaatt
    10081 acatcaccct tatatttaaa ataaagttgt gcatcacttg attcaaatct atcaatgact
    10141 ttttttacta aattatcatc tatcgttctt ttaaaaatta cattataatc tttatcatat
    10201 ataaatgaac cattttcaca tacataatat ccattcatat ctaaactatc tttgataata
    10261 ttatgtgctt gtttaaaaat tctacctgta gcaacattaa actgtactcc ctttttttct
    10321 atttcttcaa ttgctactat atcttctttt gttatggttc cattttcata tagagttcca
    10381 tctaaatcac aaaatatatg ttttatcata aattaaaagc ctccaaaaac aattttatat
    10441 tatagtaaca cttcaaatat atccaatatc ataacaactt aaagcttttc taattgtatt
    10501 ctcaattcat taagtaaatc tctagtagct cttaatctta tctttcttct atccccatta
    10561 aatatatttt tctttactat tgtttttcca tttatatata ttgcagtata aactagtccc
    10621 acaggcttct ctttggttcc tccaccaggt ccagctactc cagttgtgga tatacctata
    10681 ttagctttaa gtcctttagc aacgccctca gccatttcta tagctgtttg ctcacttact
    10741 gctccaaact cttccaaagt ttctcttttt actcctaatc ttttcatttt agaatcatta
    10801 gaatatgtta cacatccttc aagaaataca gaagatattc ctggatagtt tataagagat
    10861 gaagaaacca aacctccagt acaagattca gccactgcta ttgttagatt tttttctaca
    10921 agtaacttag aaacagcatc ttctaaagca gtctcccctt cagatatgga aatatctcct
    10981 tcagtatata catatttacc aactctactt tttatttttt cttctactgg ttttattaat
    11041 ttaaaagctt ctctttcatt ttcagccttt gcagttattc ttattgtaac ttctaattct
    11101 tttgcatata aagcaactgt tggattagtc tgctcattaa ttatatcgag aatttctaat
    11161 tctagatttg actcacctat tccatataat cttaaagtct tagatactag catttcattt
    11221 gtgaattgtt gtaagtaagg tttgacactc tcattaaaca tagctttcat ttctcttgga
    11281 ggtccaggca atactattat aaatttacca tcttttttta aaattgcccc tggagctgta
    11341 ccattattat tttttagtac tatagcatct tttggaaagt acacttgttt catattattt
    11401 tcggccattt tttttcctgt tttaacaaag aaagattcca aaacctctag tgaaggttta
    11461 tgtagttcta atttctgacc aaagtattct gcagcagttt cttttgtcat atcatcacca
    11521 gttggcccaa gaccacctgt agtaattaca aaatcacttc tctttaagct ttcatcaaaa
    11581 cattctaaaa gtctttgttt gttatctcca acagtactct gatggtatac ttctattccc
    11641 aatgatgcaa gttctttagc taaaaattga gaatttgtat ttactatatc tcccaataat
    11701 atttctgttc ctacacttat tatttcagct ttcaaaattt atcactcctt gatttatagc
    11761 cattaagact agtcttaagt tcataacaat aattttagca aaaataataa cataaataaa
    11821 gttaaaaaat catttaaaca tatctttaaa ctagattatt attctaaaac cacacataat
    11881 ataaacttcg tatatagtgg tactttcatc ctcaactgtt aattcatata attaagtatg
    11941 taaataaaaa gtttacttta aaataataaa aattaaaata ggagtgtata atatgaaaat
    12001 agcagttata atgggtggaa tatcatcaga gagagaagtt tctttaaatt caggaaaaga
    12061 gatatataat aaccttgata aaaataaata tgaagttgta aaagtaataa tagatgataa
    12121 aaaagatata tttacaaaga taccagaaga tatagatttt gcaatacttg ctttacatgg
    12181 aaaatttggt gaagatggat gtattcaatc aatacttgag actatggata taccatactc
    12241 tggatgtgga cctctttgca gtgggatgtg tatggataaa aatataacta aaaaaatgct
    12301 tagagattca aacctaccta ctgctccatg ggttttagta aaatcagttg atgaaatcga
    12361 ctatgatgaa atagataata taggttatcc agtatttata aaaccaaact caggaggttc
    12421 aagtgtagcc acattcttta ttcattctaa ggatgaagtt gaagaagcag ttagaaaagg
    12481 tctggaagtt gacgaatttg taatgattga aaaatatata ccaggtggag aatatacttc
    12541 attcatatta aatggagaag tgttccctac aatatctata aaatctgatt caggattctt
    12601 tgattatgaa gctaaatact cagttgaaaa aggtgcaaag gaagaagttg tttacttaga
    12661 tgaagaactt caaaaaagag taaacgaaat ttctgagact tgttggaaaa tttttaattg
    12721 caaagcatat gtaagagttg atatgattat aagtgaaggt attccatatg ttcttgaact
    12781 aaatactctt cctggaatga ctcaaactag tttaattcct agaagtgctg ctgctagagg
    12841 tattaagtac agtgaactat tagataaact tatagaatac tctttaaatt agatgaaata
    12901 atttgaggtg gtaatttgat attttcaaat ctaaaactaa atgataatga accaatttat
    12961 atacaactta aaaattatat aagtgatatg atatcaaaag gactaattcc agacaatagt
    13021 aagctccctt ctacaaggga gcttagtcag cttttacaag ttagccgaaa ttctgtagtt
    13081 ttaacttatg aagaattaaa atcagaagga ttaatctact ctatttcagg aaaaggtaca
    13141 tttgttaaat caaagaataa gtcttcaaat actacatggt cattaaactg ggattgttta
    13201 gagaatacat actctaaaaa agccaatgaa ttggacatta taaaaagtga aattccttgg
    13261 agctctgacc tgatttcctt taaaagtatt tctccagatg gagatttatt cgacatggaa
    13321 gaattaaaaa aatccttttt aaatagaatt tcactagaag gacataaatt actcaactat
    13381 ggatatgcac aaggttataa gccccttatt gactatttac tagaatatat gacaaacaag
    13441 ggtgctgata taagtaataa agatatacta ataacaaatg gattcacaga aggctttgat
    13501 attattatgt catcttttac ccaagaaaaa gactacataa tatgtgaaaa tcctactcat
    13561 aatactgcta taaaaattat gaaatctcat aacctcaata tcttaggtgt agatataaat
    13621 gaagatggtt tggacttcaa tatgctagaa gacaatttag ttaagtataa aaataaaata
    13681 aagtttgcat acattacacc ctcttatcac aatcctacag gaattgtaat gactcctgaa
    13741 aataggtaca aattctataa tcttatgaaa aaatacaata tagcaattat agaagatgga
    13801 tttaatgaag aattactcta caatagttct catatatttc ctatctgttc cctagataat
    13861 atgaataatg gggtcgtata tattggtagt ttttcaaaaa ttttatttcc tggaatgaga
    13921 attggatgga tatttgcaga taaaaaagta atcaataaac tagaaagtgt aaaaaggtgc
    13981 agaaacatac atgtatcctt tttagaccaa ggaattttat ttgattattt aagtaatgga
    14041 ggttttgaaa aatacattaa aaaaatacgt aaattctatg gggacaaatt taactttgca
    14101 tataaatgta taaaaaaata tataaaaaca gaatatatct tgggtgatgg aggtttgcat
    14161 atatttataa aactaaaaaa tatagatact agagttttat tagaaaaatg ttatgaaaaa
    14221 aatgttatat ttatgcctgg agatttattt tttacagata actctggttt tgatacttta
    14281 agactcggat tttctaggtt gtcttttgaa gacattgaaa ttggaataaa aataattgga
    14341 gaaactataa atgaaatgtt ctaggttaac taaatattgt tagcctagtt tatttttatg
    14401 aggtataata tatatagttt atatgaatct aatactgggg gataatatga gtaaaaagtc
    14461 aaaacgaaga aaaattaata aattaaaatt aacgattgta ataactgtat tatttcttgc
    14521 tttattatct atatatgaga tactgttctc taatcccaac aaaaaaggta atataaagag
    14581 tcaagaaact atgcagaata aaaataatac aacagatgat tctaaaaata atcaaagctc
    14641 taccaaaaag caggaagata ataatatcaa gcctactttt tcatattctt caataccaga
    14701 taatataaaa aataaaatga ttggtaaatc tatgcctact gatgaaccta taagctttga
    14761 tagtctatct tatttaaaac ttacatatta tggatttgat gaaaaaactc atcaaggaga
    14821 aatgatagta aacagtgaac tagctccaga agtagtggat atttttaagg aattatacga
    14881 aaaaaaatat ccaattgaaa aaattaaatt aatagatgac tatgatgctg tagatgaaaa
    14941 atctatgtct gataataata cctcatcatt ttgttataga actatagctg gtacaaatgt
    15001 agtttcaaat catggtaaag gacgtgctat agatataaac ccattacaga atcctcaagt
    15061 ttctggaaat gatgttacac ctaaaataag tacagtttat gctgataggt ctagcacaaa
    15121 atttggaatg ataaaaaaag gtgatgattg ttataatgct tttgtaagca gaggttggag
    15181 ttggggtggc tattggaaaa acccagatta tcaacatttt gaaaaataat agattagaaa
    15241 taaaggtgaa ttatatgaat ttaatgacat tggaaaatat aagtaaaagc tattctgaaa
    15301 aaaaattact agaaaatata tctcttggaa taaatgaggg ggaaaaaata ggacttattg
    15361 gtgtaaatgg tactggtaaa tctaccttac tcaaaattat tgcaggagtt gaagaaagtg
    15421 agactggtaa tataacaaaa actaatggta ttaggataga atatctacct caaaatccaa
    15481 cttacaatga aaattcaact gtacttgaac aagtatttaa tggaacttct gaagaattaa
    15541 agctacttgg tgaatatcaa gaaatcctag aaaaacttaa ttcaaacttt acagaggaat
    15601 taaataaaaa attattatca gtacacgaaa aaatagatgc cttaaatctt tgggatttag
    15661 aaagtgaagc taagtcagta cttacaaagc ttggtataaa tgactttaat caaaaaatag
    15721 cagaactttc tggtgggcaa agaaagagag tctctctggc atcagccctt attacacctt
    15781 gtgagttttt gatactagat gagcctacaa accatctaga caatgatact atagattggc
    15841 ttgaggaata tcttaattca agaaaaggct cattgcttat gataactcat gatagatact
    15901 ttttagaccg tgttacaaat agaattattg aactggacaa gggtagatta ttcagttatg
    15961 atgggaatta ttcaatattt ttggaaaaga aaatggaaag actttcgcta gaagcaagta
    16021 ttgaagataa aagacaaaat ttaataagaa cagagcttgc gtgggtaaaa cgaggagctc
    16081 aggctcgtag cactaaacaa aaagctcgtt tacaaagatt tgatgaactt atgaatagag
    16141 attcttttaa acctgatgaa aatctcgata tatctgttgc atcaagtaga cttggaaata
    16201 aaataataga aatacacaat atatctaaat catttgaaga aaatactgtt atagataatt
    16261 tagaatacac tttaactcgt acagatagaa ttggtataat aggcaaaaat ggtatgggta
    16321 aatctaccct tataaatata cttaatggag aaatagagcc tgatagtgga tatatttcaa
    16381 ttggagaaac agttaaaata ggttgttttt ctcaagacga ctctcatatg aatattgata
    16441 tgagggctat agactatgta aaagaagcta gtgactatat agaaacttca gatggtacta
    16501 ggattacagc ttctcaaatg tgtgaaagat tcctttttaa tggtactatg caatatactt
    16561 tgataggtaa attatctggt ggtgaaagaa gaagactaca tcttcttaaa atccttatga
    16621 cagctcctaa tgtgcttctt ttagatgaac ctacaaatga tttagatatt gaaacgctta
    16681 aaatattaga agaataccta gacgaattta aaggtgtagt agttacagta tcacatgata
    16741 gatatttctt agatagaatt tgtaataaaa tatttgcata tgaaggtaat ggaaaaattc
    16801 atatctatac aggtaattac agtgattatc ttatttatag agagattcaa ggaattgaat
    16861 ttgaagaatc taaaagggaa tcagttaaaa aagatgactc tactacccta aaaaaagaaa
    16921 aacctaaaaa tgataaaaag cttaagttct catataatga acaaagggag tttgaaaata
    16981 ttgactctga tatagaaaaa ctcgaatcta aaattgcaac acttgatgaa agtactgcaa
    17041 aattttcaac tgattttact aaacttcaag aaattttaga tgagaaatct aaactagaaa
    17101 aggaacttga atacaaatat gaaagatggg aatatttaaa taatctagct gatgaaatag
    17161 ctaataataa gtgatattaa aataatctta agtttaataa gttttgcttt aaatctatac
    17221 tttataaata ttttaaaggt agtgtctcaa aatgaacttt ttagttttat gagacactct
    17281 tttttatgag aaatcaaata tgttttcatc atttcaacaa tacaaaagag gcttatctct
    17341 attttgagac agcctctttc ataattacct tctaatttat atgctttaat atatctataa
    17401 taattcttat tatatctata tatccagtct ttcaatatag tgacaattaa cttcaatatg
    17461 atttaaaaat actaacaacc tttcataaag tggatgagat tcttctccat atttagcttc
    17521 taggttcttg cctatttctc taacagtcct ttgaccatca atttgtaaaa aaacaaaact
    17581 ggaatattca tctagttcta tttttttgta tttaggtatt ctagctttta actttctaaa
    17641 aaacttttga attttatggt cctgtttttc aagtatagta acaacactat tttcagctac
    17701 ttcatattca agtccatcag taattttaaa tacaatatct aaaacatcat tactcttgct
    17761 cattattttt tactttagat aaaacaatag gtaatgttgt aagcacaact aaaactacta
    17821 ataaagcaat tgccattgaa tttgttgcag caaatccact tggtaccttt ggagttacaa
    17881 ctccagttac ttgtaatatt atacctatta aaccaatgat agaaccacca gcaacaagac
    17941 cagaagataa acttatacca ttagaaactt taacttcttt ttctttttca gttttagata
    18001 ctaattcaac aaataaacga attaatgctc caactaatat tatagaagtt gttgcaattg
    18061 gtaaatagaa tcctatagct atagtcatta ttggtaaatt taatgcatat agaactattg
    18121 ccataaatac tccaacaata atcataaccc aaggtaaact acctgacata ataccagaag
    18181 ttaatgttga cattaagttt gcttgtggta atgcaaattg tacattatca ccagttgctc
    18241 taagttggtc agaaagtaat aaaattactc ctacaacaac tataacacca actatacttg
    18301 caattgtaaa gtaacgttgc atttcgtttt tgctaccacc aataatataa gttacttttt
    18361 gagattgagt ataacctcca gctatagcaa tagcaacaac tataaatgaa ccaaataaaa
    18421 gtaatgattt attagcttct aaatcagtcc atcccattat aacaaacact aatgttacaa
    18481 taactagaga agctatagtc ataccagaaa ctggaagatt tgatgttcca attgttcctg
    18541 ttaaacgacc agctactatg acaaataata aagataataa aagagatatg atagctccaa
    18601 taattgccat aacaatgtta ccagaaatta agaatgctgc taaaaatcca ataactactc
    18661 cacctaataa aagtatcatt tgtatagatg aaccttcttc tccttctcca gcacttgatt
    18721 tagctttaag tgtttctttt atagaagcga ttatagttgg tataagtttt attgcaccaa
    18781 taatacctcc acaaagcatc ataccagcac ctatatattt tacataacta ctagatattg
    18841 ctccgacatc catttggtta agaggcattg caggattatt ccataccata gctccatctt
    18901 tagccatatc tgtaaagtat cctattaaag gtgctatacc aaagtttgat aaaatacttc
    18961 ctgcaaacat tgttaaagaa acttcaagcc ctactataaa tccaattcct aaaagtagag
    19021 gatttacttc aatatcaaat ttccatttgt agaatttgct tcctacaaga ctcattacat
    19081 tgtttgctac atttaagaat gaaccagtta atacagtaat aaatccactt attacaaatc
    19141 caattcccat gtacttaatt gaatctccac cagcctctga agcaacaagt gtctcagata
    19201 tagccattga ttctggatac ataagtttac catgttcttc aactattaga tagttgtgaa
    19261 ctatagcagc aattcctata ccaaataaaa ctccaccaac tccaacagct aggccttcaa
    19321 agaatgtaat ttggcttcca attaatataa ctgctggtaa tacgaaaata aatccacttg
    19381 caacagattc tccaccactt gacatccctt ggattaagtt tttaccaaga ataccctttg
    19441 aacgagcaaa tgctccaaca aaagcagaac ctattatagc tcctggaata cctgcagcaa
    19501 ctgtaagacc ggctttcatt ccagagtaag ttgtagatgc ggcaaaaatg gcagctaaaa
    19561 taataccgat aatcagtaca gctacatttc caccggttct ggacttatct gtgatatatg
    19621 gaacgtaatc ttttccacta acctcaccat aagcaccctt aggtaatttt ttgttcataa
    19681 aattttcacc ccttttcaat ttgtatatat tataacatat atacatataa aacttaactt
    19741 tttattattt tacaaatagc gagtcaaaac tacta
//
LOCUS       DAEQJM010000066        19643 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.066, whole genome shotgun sequence.
ACCESSION   DAEQJM010000066 DAEQJM010000000
VERSION     DAEQJM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19643
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.066"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            218..1369
                     /locus_tag="KRQ43_002938"
     CDS             218..1369
                     /locus_tag="KRQ43_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBH2743282.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDVVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1415..2590
                     /gene="thiI"
                     /locus_tag="KRQ43_002939"
     CDS             1415..2590
                     /gene="thiI"
                     /locus_tag="KRQ43_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBH2743283.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2746..3549
                     /locus_tag="KRQ43_002940"
     CDS             2746..3549
                     /locus_tag="KRQ43_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH2743284.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGIEMARDIHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3792..4433
                     /locus_tag="KRQ43_002941"
     CDS             3792..4433
                     /locus_tag="KRQ43_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBH2743285.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            5846..7516
                     /locus_tag="KRQ43_002942"
     CDS             5846..7516
                     /locus_tag="KRQ43_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HBH2743286.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYEEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(7638..8372)
                     /gene="pflA"
                     /locus_tag="KRQ43_002943"
     CDS             complement(7638..8372)
                     /gene="pflA"
                     /locus_tag="KRQ43_002943"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBH2743287.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(8532..10763)
                     /gene="pflB"
                     /locus_tag="KRQ43_002944"
     CDS             complement(8532..10763)
                     /gene="pflB"
                     /locus_tag="KRQ43_002944"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBH2743288.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFS
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            11056..12117
                     /locus_tag="KRQ43_002945"
     CDS             11056..12117
                     /locus_tag="KRQ43_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBH2743289.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGRKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNRLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            12208..13821
                     /locus_tag="KRQ43_002946"
     CDS             12208..13821
                     /locus_tag="KRQ43_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH2743290.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            14096..16081
                     /locus_tag="KRQ43_002947"
     CDS             14096..16081
                     /locus_tag="KRQ43_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH2743291.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLSFGILEKPVVWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMIEELAKVKSFDEFYKIITKRR"
     gene            16086..16520
                     /locus_tag="KRQ43_002948"
     CDS             16086..16520
                     /locus_tag="KRQ43_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HBH2743292.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            16549..17109
                     /gene="srlA"
                     /locus_tag="KRQ43_002949"
     CDS             16549..17109
                     /gene="srlA"
                     /locus_tag="KRQ43_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBH2743293.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            17173..17541
                     /locus_tag="KRQ43_002950"
     CDS             17173..17541
                     /locus_tag="KRQ43_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HBH2743294.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            17566..18132
                     /locus_tag="KRQ43_002951"
     CDS             17566..18132
                     /locus_tag="KRQ43_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBH2743295.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            18173..18538
                     /locus_tag="KRQ43_002952"
     CDS             18173..18538
                     /locus_tag="KRQ43_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBH2743296.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTNDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            18639..19412
                     /gene="srlD"
                     /locus_tag="KRQ43_002953"
     CDS             18639..19412
                     /gene="srlD"
                     /locus_tag="KRQ43_002953"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HBH2743297.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIETEFGCKSVGYGCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
BASE COUNT         7627 a         2192 c         3398 g         6426 t
ORIGIN      
        1 atatattgta ttttataata tatttttgta aggtatagta taagtatatt atattttact
       61 ataaaaattt gtaataaagt gaaaaaacta gcttttcatg aaataatatt ttataattta
      121 agattgtctt tttaataaag attaacaaaa aaaatactat aattagtggt ataatagtta
      181 gagttgaaga ttttaaataa aggtaggtgt aattaagttg gaaatatact tagacaatag
      241 cgcaactaca aaaccttatc aagaagttat agataaaatg gtttatgcac ttaatacgga
      301 atatggaaat ccttcttctg tccatagaaa aggtgtagaa gttgaaaaag ctataaaaga
      361 agtaagacaa gatatagcta aatctctagg agcgaaagaa aaggagattt attttacatc
      421 aggtggtaca gagtgtaata atactataat aagaggtatt actagtttaa ataaaaaaag
      481 aaaaaatcac ataatatcta ctaacataga acatccttct gttttaaata cattaaaaga
      541 tttagaagaa gatggttttg aagtaactta tttagaggtc ggaaaagatg ggaaaataaa
      601 tatagaggat ttaaaaaatg cgataaagtc aactacatgc ttagtaagca tgatgcatgt
      661 taacaatgaa ataggaacta tacagccaat aggtgaagtt ggaaagtatt tgaagggttt
      721 aaaagaaaaa atttatttcc atgttgatgc tattcagtca tatggaaaaa ttaattttag
      781 accatctaaa tacaatatag attttatgag tgtaagtgca cataaatttc atggtccaaa
      841 gggaattgga tttatgtata taaaagaaaa taatcgcctt aagcctatgt taacaggtgg
      901 tggtcaggaa attggaatta ggtcgggaac agaaaatgta cctggaatat atggtcttgg
      961 agaagctgtt agaatactaa acaaagattt agatgttgtt atttcgaaag taaataactt
     1021 aaaaaatata ttaaaaaatg aaataattga taatatagaa gatataaaaa tcaattctcc
     1081 agaagatgga gtatgtcata tattaaatgt atcatttaga gggacaaaag gagaagtttt
     1141 acttcattac ctagagcaaa aaggtattta tgtatcaact ggctctgcat gttcttctaa
     1201 aaagaaaggt agttacgtat taaatgctat aggtcttaca aatgaagaaa taaatggaac
     1261 aataagattt agtttatctg atatgaatac agaagaagaa atgttagaag ctgtgaaagt
     1321 tttgaaagaa tcaatttgtg acttaaggtc aataatgaaa agaaaataaa gaatactgta
     1381 tagatagtga taataaatta gtttaagagg tgaaatggtg tataatatat taatagtaaa
     1441 gtatggagaa attggagtaa aaggaaagaa tagatatata tttgagaata ggcttataag
     1501 aaatataaga aatatgttaa aaccaattgg aagatttaat gtatataaag agtatggaag
     1561 aatatatgtt gatttagaag actatgatta tgaagaagta attgaagaag ttagaaaagt
     1621 atttgggata gtgggtgtgt gccctggagt aagagctaaa aaagattatg atacattaaa
     1681 agaaatagct ttaaaaatgt tagaagaaaa aatagaggct ggatataaaa cttttaaggt
     1741 agagtcaaga agaggagata agtctttcgg gttgacttct caagaaatga gtatggatat
     1801 aggtggatac ttattatcaa aggtaggaga taggattaat gttgatgtaa gaaatccaga
     1861 agttaaaata aagtgcgaat acagagaatt tcatactatg gtctatagtg atactatacc
     1921 tggatatggt ggattgccac ttggaacgaa tggtagagct atgtctcttt tatcaggagg
     1981 tatagatagt ccagtagcta catggatggt tgcaaaaaga ggtatggagg tagaggcagt
     2041 tcacttccat agttatccat ttacaagtga aaggtcacag gaaaaagtta aggatttagc
     2101 taaaatactg gcaaaatact gtggtagagt aagacttcat aaagttaaca tattagaaat
     2161 acaaaaagca attggtgaga attgtaatga agaagaagct actattcttt caagaagatt
     2221 tatgatgagg atagcacaga gactttctga aaaaagacat tgtgatgctt taattacagg
     2281 tgaaagtatt gggcaggttg catctcaaac tatacaaggg cttacttgta ctaatgccgt
     2341 tgtagactta ccagtgttta gaccacttat agcaatggat aaatcagata tagttgatat
     2401 agccaaaaaa atagggactt ttgaaacatc tatagtgcct gaagaagatt gttgtagtgt
     2461 attttctcct agaaagcctg tcactaaacc tagattagag aaaatagaaa aatctgaaac
     2521 agcacttgat attgaaaaat tagtacagga tgctattgac aaaatagagg tagaggatat
     2581 tgagttttag catacaagtt atttaattac taaattgaat attgagtata ttagtagttc
     2641 tgtaagtata ttagtagttc tgttgaaagg atttatgtag acaatttatt aatatatagt
     2701 atttaaaaat aagtactata attttattta atgggaatga ttattatgaa taaaaagggt
     2761 tttacattaa ttgaattgtt ggtagttata tctataatag gaattttagt tatagtagct
     2821 gttccagcgt tatttagaaa tatagaaaaa agtaaggcag ttacatgtct ttctaataga
     2881 gaaaatataa agactcaaat tgttattgca atggctgagg aatcaagtaa agacaagaat
     2941 gaagtcataa aagaggtatt agaaaacaaa gatggtaagt actttgaaac agaaccaaag
     3001 tgtaagtcag gtggaatata ttcagcaacg tttgatgatg gttatgatgg aataactgga
     3061 atagaaagca ttgcaaaagt gtatgttact tgtacaaaac atccagatgg tattgaaatg
     3121 gctagggata tacatcaaag tatgaaagat ttgattgcat catttgcaca agacccttct
     3181 ataataccag gagcttcaaa gggcaatgat gattttagaa aatatttatt agacaataaa
     3241 tataaaaatg ggtggcctac aattccagat gaatttaagg caaaatatgg attaagtaag
     3301 gatacactat atatacaacc atatgcatat aatcctacta aatctgatgc tactgtagtt
     3361 gtatttgcaa ataataagac tggaggtaat tggtatactt ccctagttta cgattatgat
     3421 gaaggtagat ggtataaagg taaaaatggt atttctgttg caggtaggtc atgggatgtt
     3481 gacacagata gtgttaagtc tgtaaaaaca gagattcatt ctaaagaggg atggggtcct
     3541 ttaaattaat atatcatgtt ttattaatct ggtattgatt aaactataga aaagagcagt
     3601 ttctatagat gacgaatacc agattttcat ttatatgtat aattaagata tattaaaagt
     3661 atttatattt ttaagtcttc acatacaagc taaagataat tataataata ttgtaaagaa
     3721 atttaattat aagattaatt ttctgaagat ttagtatttg tactaagaaa tacataaaaa
     3781 ggggaataga tatgaataat aattttcaag acaaccaaac aataaattta atacaaagtc
     3841 gtagaagtat acgaaaattt acaacagagc aaattagtga tgagcaagta aacacattat
     3901 tacactgtgc atttgcagca ccttcaggat gtaataaaca gccttggcac ataactgttg
     3961 tgcaagacca gaaactttta aaagagatta gtgatgatac tttatctagg attcatgaag
     4021 tgagtaatgt tgagataaat aaaaacttta agttatttta tggtgctcca accgttttat
     4081 ttatttctta tgatgaaagt agttcatggg ctccatatga tataggaata cttacaggga
     4141 atataacaac agctgcacaa gcactagggc ttggaagttg tataatagga atggttagag
     4201 gtttatttac acctgttgaa caaggggata ttgaaggtct tgtgagtgta ttggataaag
     4261 aagatgtaaa ggaatcagag tcaataaaga tgaagtttga tacaaataaa aaatacagag
     4321 aactacttga tataccagaa gggtattctg taccatttgg tattgctgta ggtattccag
     4381 atggaaattt accaaatgct agagaggtag tttacaaagt ttccagagtt taggataaag
     4441 tattgcaaga accaatcagt tacttgaaga attaaaccag taatatacaa ataaattgat
     4501 ggaagaggaa gctatttaaa aagtagttta gatttttcat tgtaaaataa ttaaataaag
     4561 aataaggtga taagtatttt atttattatc ttattctttt ttatttttgt tttgtagaat
     4621 gataaaaata aggattaagt gtaataaaat agaaaacaag tatgttaatt ttaagtatat
     4681 gctttaaaat ttatccaagt taaaaattta agatatcttt tcagtataat ggaaaaaatg
     4741 tcaaaatatt gaaataggga aaaaatagtg atataataaa aaaaatagag aaaaaaagta
     4801 acccttagtt gtaaaaaagt tactatttat tgaaaattta gatacttttc taaaaattat
     4861 ctatgttaat agttaaattt atgaacattt tttgttttta tgttaggata tttcttagaa
     4921 atgaaatact tcttaatttg atttgatatg tatattttta tagctatttt attataaaaa
     4981 aaaagaaccc ttttacaaca aatggaaact atgtacgtaa taattaaaat aaaaaatatt
     5041 attttatatt tataaacatt gacattctaa ttctgtagtg taatcgtatt ttttattaat
     5101 tcttataaaa tcaatgaaaa taaggatatc cattttaaag tacataaatt taaaaatcca
     5161 gaaaaatata cttaaattat gtaagcaaaa gaggggttga atcggctgaa aatgtaatac
     5221 tagtaaatag tacatcaatc ctagataccc tgtaagcaac tctattttca tgtactaaaa
     5281 atgtacctat tttattaact gaaaagaata aattaaatgt aagtacataa taagagataa
     5341 aaaattaaaa gcaaaaaata tttatataaa taaatataaa aaatgatata atccctatta
     5401 aaaaatttat agatgatgaa gaaatatcaa aatcttatat tataggaaga ggcacttctt
     5461 tgccaaaata tatagaaaag caataccaaa tccaaagaga ataggctgag aaaaaataaa
     5521 acaaattcaa gagtaataga aaagctttat agaataaaga actgagaact ctttatataa
     5581 taaaaaatgg acttttaaga gaaaatgatt taataaatga tttaacatgg tgttttagca
     5641 ggtgaaaata aatcaccagt aatgattgta gaaaaattac tttatgaatc tcaaaaaaac
     5701 ttagttaaga gtaagagatt tgataagata actaaagttg gggaaatgtg tttgatgaga
     5761 taaaaaaatt agtaaaatag tataatctaa ataagaatat tttgttgatt aaactacact
     5821 aatagtaata ttgtaggggg aaaagatgag agaagaatcg aactctttaa gtttagacca
     5881 tatagaaatt ttctttgaac ttttatctca aagtacagaa gattatatat ttttttggga
     5941 tataaatagg aataaattta aaatttcttc agcaattttt gatgaattta acttaagtaa
     6001 agagatagaa tctgatttag tcaattgttg gagtaaaatt gtttatccgg atgatgttca
     6061 aatatggaaa gatgatatac aagaattact acatggaaaa aaaggtgagc acaatttaga
     6121 atataggttg attaataaat atgaagaaat agtatggatt tcttgtagag gtaaagttta
     6181 tgtgtcggat gacccaaaaa ctatatttct agtcgggaga ataaagaata ttggtgaaaa
     6241 aaataaattt gattctatca caggaacgtg gaatagagaa caatttgaac atagaatgaa
     6301 ttatcttata aaagagaaaa tttataaaaa tggtgctatg tttatcatgg atattgataa
     6361 ttttaaaaat ataaatgaaa aatatggaca ttcttatggt gacaaagtat tgcgtgcaat
     6421 tgctactgaa gtattagaat atcttccaaa agatgtaaga ttgtataggt tagatggaga
     6481 tgaatttgca tttttttacc ctatgtgtac taaagaaact atagagaaaa tatatgaaaa
     6541 gatacagatg tatacaaata ctcagcatga aattgaatca aataagtact attgcacagt
     6601 gactgcagga gttgctatgt atccagaaga tggagataat tatttagatt tatttaaaca
     6661 tgctgatatt gcattggata tagcaaaaat tagtggtaaa aatagaatta agtttttttc
     6721 acaagagctc tatgaaaata aactaaaggt aatttcaatg caacaaaaac taagagagtg
     6781 cgttgaaaat aattttaatg actttgagct gttttttcaa ccccaggtaa atgctgttac
     6841 aaaagaggta ataggggcag aggtactttt aagatggcat tcgagtactt atggagaagt
     6901 atctcctgtt gaatttatac caatactaga acagagtaat ttaattatac cagttgggaa
     6961 gtggattata aaagaagctg taaaacagtg taaagaatgg cataaaataa atccagactt
     7021 taaaatatct gtaaatgtat cgtatattca gttaaaagaa gattttttta gagattttat
     7081 agtagaatgt ttagtagagt atcaattaag acctgaattt ttaattttgg aattaacaga
     7141 gaattgttgg ataccagata taaatttact aaatgataaa tttattagtt taaagggtat
     7201 aggagtatat attgcaatag atgactttgg tacagggtat tcatctttaa attaccttaa
     7261 agaactgtct gttaatataa taaaaattga aagaagtttt gttaagaata ttacatataa
     7321 tagttatgaa tatacttttc ttgaatatat tattaaatta gctcatatta taaatttaaa
     7381 agtttgtgtt gagggaatag agtcttatga agagtatgat atagtaaaaa gcttaggtgt
     7441 agatattatt cagggttttt tatttggaag acctgtaagt gcctctgaat tttataaatt
     7501 tcaactatca aagtgatgta cataaaatga gatatatagt atataaaaat agggcaaagt
     7561 ggaagttttg aagtttatta aaaatttaca ctttacccta ttttgttatg tcttctataa
     7621 aggattaata tactacacta actattatat actttcactc caaatttaga gattatttca
     7681 ctagcttttt ggacatcttc cttagtggca tcaggaacat cttttagttc ataatcgata
     7741 cctaaacttt cccatttgtg tattcccata gaatggtatg gtagcaattc aaatctttct
     7801 acatttttca atgtagctac aaattgacct agtttttcta aattatctat atcatcagta
     7861 atgccaggaa ctaaaacatg tcttatccat acaggaatat ttcttgattc taagtgtcta
     7921 gcaagtttta atgccttatc cataccaaca ccagtcaaat caatagattt ttcctcaacc
     7981 atatgtttta aatcaagtaa aaccaaatca gtattatcta aaactgggtc tatagtttct
     8041 atatctacga atccagatgt atccaagcaa gtgtgtatat cattttcttt tgctttttta
     8101 aataattcac ttaaaaattc tggttgaaga gtggattcac caccagaggc agttatacct
     8161 ccaccagaaa acttcataaa agaagtatac ttaagagcat ccgttattat ttcatcaact
     8221 gtgtattctt ttcctgattt aatatcccat gtatccctgt tatgacagta tttgcatcta
     8281 agaggacacc cctgaaaaaa taatatatat cttattcctg gtccatctac agtaccaaac
     8341 gtttctatag aatgtatctt tcccttaatc atagagttca cctcacaata tattttaata
     8401 accttatcaa tagttataat atttgtctaa aaaaggccat cttataccag aaataattca
     8461 aatataagat agccttttat ttttattttt tacacagtag taatcttagt taaagtataa
     8521 aaatttaaag actaagccat tttaccgtgg aatgttctgt ttataacatc taattgttgc
     8581 tctttagtta attttatgaa gttaactgca tatccagata ctcttatagt taattgtgga
     8641 tattcttctg gatgttccat agcatcttct aaagtagctc tatcaaatac atttacattt
     8701 aagtgatgag cattttgaga gaagtatcca tccatcattg cagaaagatt gtttattctt
     8761 tcagtcatat cttttcctaa agcagcaggt actatagaga aagtattaga tataccatct
     8821 tgagcatgtt catatggtaa tttagcaact gaagataatg aagctaaagc accattagta
     8881 tctctaccat gcattgggtt agcaccagga gcaaatggag caccagctct tctaccatct
     8941 ggtgtattac cagttttctt accataaaca acatttgaag ttattgtaag tatagattga
     9001 gttggataag aatttctata agttttattt tttcttattt tattcataaa gctttcaact
     9061 aactctacag ctatactatc aactctatca tcattgtttc cgtattttgg ataatctcct
     9121 tctatttcaa aatcaacagc tattccttgt tcatttctaa tagttttaac cttagcatgt
     9181 tttatagcag ataatgagtc tgcacaaact gataacccag ccataccaca agccatagtt
     9241 ctaaatatat ctctatcatg taatgccatt tctaatgctt cataagaata tttatcatgc
     9301 atataatgta ttacatttaa agtatttaca tataatgttg ctaaccaatc agtgaatggt
     9361 tcaaatttac tcataacttc atcataatct aagtactcag aagttatagg ttcaaatctt
     9421 ggtccaactt gaacaccaga tttctcatct acaccaccat ttatagcgta taataaagtt
     9481 ttagctaagt taactctagc tccaaagaac tgcatttgtt taccaattct cattgcagat
     9541 acacaacaag ctataccata gtcatctccc cagtatgctc tcattaaatc atcattttca
     9601 tactgtactg aacttgtatc tatagatact ttagaacaga aatctttgaa tccttgaggt
     9661 aatttagttg accatagaac tgttaagttt ggctctggag aaggtcctaa tgtatataga
     9721 gtatttaaca ttctaaatga gtttttagta actaatgttc taccatctat tcccatacct
     9781 cctatacact cagttaccca agttgggtct ccagagaata ggttattgta atcaggagtt
     9841 cttaggaact taaccattct taatttcata acaaaatggt ccatatactc ttgtaattct
     9901 tcttctgtta cgattccagc ttttaaatct ctttcaaagt atatatctaa gaaagtagat
     9961 gttctaccta aagacattgc agcaccattt tggtctttaa cagcacctaa ataaccaaag
    10021 tataaccatt gtacagcttc ttttgagtta gttgctggtt ttgatatatc aaatccataa
    10081 gattcagcca tttttttaag ttcatttaaa gctgatattt gctcagttat ttcttctctt
    10141 aatctgataa cttcctcatc catgcaagaa acttctaatg atttcttttg ctcattttta
    10201 tcttctatta aagcatcaac accgtataga gcaactcttc tgtagtcacc aattattcta
    10261 cctctaccat aagcatctgg aagacctgtt attataccag attttctagc agctctcatt
    10321 tctggagtat aaacatcaaa aactccttgg ttgtgtgttt ttctgtattt agtaaatata
    10381 tcttttattt ctgggtctaa ttcatatcca aaagcttcgc atgaattttc aaccatcttt
    10441 ataccaccat atggcatgac agctcttttt aaaggggcat ccgtttgtaa cccaactatt
    10501 gtttctaatt ctttatctaa atatcctgga gcatatgcag ctattccaga aacagttttt
    10561 gtatcaacat ctaaagtacc accattttct ctttcttttt taaataggac cattgcttcg
    10621 tcccataatt ttttagtatt ttcagtggca ccagctaaga aagagtcatt tccctcatat
    10681 ggagaatagt ttaattgtat aaactctcta acatttattt ctttagtcca tcttcctgtt
    10741 ttaaatcctt gccatgcatt cattaagtat ttcctcctta gatttaaatg ataaataata
    10801 ctattaaaat tattttttat atacttaatt tattttatat atttttttaa aaatatattt
    10861 tctaatataa taatatcata ttattcgtat cctgtataca taaaaaataa aaaattgtcg
    10921 ctttaaagta taaaacagat tatatgttaa taatgtggtg aaattatacc catatataaa
    10981 taaaataaaa caaataaata gctaattaag gagaaaatat tttttatttt ttgtttagga
    11041 taaataaatt ttattatgga aaaaagaaaa agcatacatc ttcacaaatt gaatatttat
    11101 ttaatagggg gaggtgatag attgtttatc acagtggtat tatttttagt aggtttccta
    11161 ttaattacta aaggcgcaga tatctttata aattgcactg tagagatagg tagaaaaacg
    11221 aatatatcag aaattatact tggagctact atagttagtt ttgcaacaac attacctgaa
    11281 tttacagtgt ctctacttgc ttctattgat ggtcatacta ctatgagttt aggaaatgca
    11341 gttggttcta taatatgtaa tacaggatta gcattagggt tggttgtttt tataagtcca
    11401 tttaatgtag ataaaaaaat gtttttttct aagtctttac tattaatagt atccgttata
    11461 gttttaattt tattgagttt agatggagtt ataacaagag gtgattcatt attacttata
    11521 ataatattaa tcttttatat ggttaataat tatagaagtg tcgttggaaa atctgatact
    11581 aaaaatagaa atattaaaaa taacactatt aaagacatat ctactaaaaa agggaaaaat
    11641 tatagaggtt tttccgtatt agaaattgta aaaatactat tactttttgc tacaggattg
    11701 ataatgatga taataggttc acaaatcctt atagagagtg gagtaataat agctagtttt
    11761 ttaaatatac ctcagggtat agtaagttta actataatag cacttggaac ttctctgcca
    11821 gagatagttt cgtcgattac tgctataaga aaaaatcatc atgaaatatc agtaggaaat
    11881 attttgggtg caaacatatt gaatatagta tcagtaatag ctgtatcagc aataccaaat
    11941 aacataccaa tactatctca aaatagacaa ttggatatac cattcatgat attattatta
    12001 ttaatagtaa taataccaac acttaaatct aatagactta gtagaataca aggtatattg
    12061 atgttattca catattttct gtacatatca attttgtatt tcatgtatat tatttaacta
    12121 tactgtttaa aatattaatt gcagaatatc ctaaaaaagt atataatgga taggttaaga
    12181 ttaattgata acggagagga ataatatatg aatataacaa agtttgaaga tttaccaata
    12241 agtgagggaa taaaaaaagc tatagctgaa atggggtttg aagaaccatc tcctatacaa
    12301 gcacagtcta tacctgcgat tttgtcaggt aaagacgtta taggacaagc tcaaactggt
    12361 acgggaaaaa cagctgcttt tagtatccct atactagaaa caatagaccc aaataataga
    12421 agtttacaag ctgtagtgct ttgtccaaca agagaactgg caatacaagt atcaacagaa
    12481 ataagaaagt tagctaagta ttcgcacgga ataaagacat tacctatata tggtggccag
    12541 ccaatagata gacaaataaa atctctaaag agtggtgtgc aagttgtaat aggtacacca
    12601 ggacgtacaa tagaccatat caatcgtaaa acattaaaga tggataatgt aaaaatgatt
    12661 atattagatg aagcagatga aatgctagat atgggattta gagaagatat agaaatgatt
    12721 ttaagtaaga ttccagaaga aagacaaaca actttctttt cagctactat gccaagagga
    12781 attttggaat taactaagag atatcaaaaa gacccagagc atataaaagt tgttagaaaa
    12841 gaacttacag tttcaaatac aaagcaatac tatatagaaa ctaggtcatc aaataaatta
    12901 gaagtattat gtagattagt agatgtatat gaccctaaac tatctgttgt tttctgtaat
    12961 actaagagaa aagcagatga attggtagga gatttacaag caagaggata ttttgcagat
    13021 gcattacatg gtgacttaaa acagactcaa agagatatag taatggataa gtttagaaat
    13081 ggtacaatag atatacttgt tgctactgat gttgcagcta gaggtataga tgttgatgat
    13141 gttgaatgtg tattcaacta tgacttacca caagatgaag agtattacgt tcatagaatt
    13201 ggtagaactg gtcgtgctgg tagagaaggt atgtcattta cttttgtatt tggaaaagaa
    13261 atgagaaaga tgaaagatat agaaagatat actaaatcta aactaataaa gcataatata
    13321 ccaacaataa ctgatgttga agagaaaaaa gtaggtactt tctttgcaca agttaaacaa
    13381 actatagaag aaggtcactt aactaaacaa ttacaatggt tagaaggttt ctgtaatgat
    13441 gaagattatg caatggttga tatagctgct gcacttgtaa aactatctct aggtgaagaa
    13501 atgaaagaag aaataataga agaaaaacct agaagagagc gtggagatag aaaaggtggt
    13561 actggagcta aagatggtat gattagatta tttatcaata ttggtagaaa tcaaagagta
    13621 caagcaaaag atatagttgg tgctatagct ggagaagttg gaataccagg taaagtagta
    13681 ggtactatag atatatatga taagtatact tttgttgaaa tacctaaaaa agatgcaaaa
    13741 acagtaattg aaaagatgaa agatattaag ataaaaggta ataagattaa tatagaaaaa
    13801 gcaaataaga agaaaaaata acgtatagta tacaaaacta taattagaaa atatataaaa
    13861 taatatattg gatatttaaa aagcctgatg tgttttcaaa acagatagta gataatctgt
    13921 aagagttaac agcataaggc ttttcttgtt ttatatgata ttatgatttt ccagatcgtt
    13981 gtgaaaaatg tatattagtt cctttttttc aaatctgatt tgaaaaagag aatattaatt
    14041 atctatatag tttagattat aataaaaaat gtaagataac aaaggggaga aaaagatgtc
    14101 aatgacttat atggacccta gggttttttt gattttagaa atggtgttag aagaagacac
    14161 aaatactcta gaacaatttt caaatgtttt gggtgttagt actaggacta tcagaaacta
    14221 tataaaccag attaatcgag aattaaaagg tggtattgct aaaatagtta aaaatgaaaa
    14281 aggtacatat agtataagaa ttgaggatga aagtaaatta attgagattg taaattttaa
    14341 tagaggaaag ctatcaaatt ttataaattt aaattcacct gatgaaagaa taaattatgt
    14401 tcttgatatt ttaactatga ccaacaatcc aattaccata gatgatttgg ctgaagagat
    14461 atgtatagga agaacaacat taataaagga tttaaaaaaa gcagacagaa ttttagctga
    14521 atatgattta gaattaaaaa ggaagccaaa tataggtatg attttagttg gtgaagaaat
    14581 ggatataaga ttattaatcc ttgatagatt gtatgaaaat tatattgatg tcttggaaaa
    14641 cgttaatcag ataaatttag ttaaagatta tgatattgaa tgtcttagag atgaattaaa
    14701 aaagttgttt aaaaaagaag aactctacat aacagaacag gtcttgagag atgttgaaag
    14761 atatataatc atgtctgtct taagaaatct aaatgggtac aaatttgaaa agatagataa
    14821 gagatttgaa gtgataagat gttcagatga atatacttta ggattaaagc tcaaagcttt
    14881 attggaaaag atatttaata tagttttaaa tgaaaaagaa accatatttt tgacaatgcc
    14941 attaataggt agaaaagctc ctagtacaaa attagcactt agcagtataa agataaatga
    15001 tagcgtaaag gaagttgtag atgaagtaac tagtttttta ttagagacct cagggattga
    15061 ttttaaagaa gataaaaagc ttatagaaaa tttggaatat cacttgtatt ttgcacttaa
    15121 tagaatgaga ttcaacataa gggtaaaaaa tcctctttta caagaaataa aggaaagata
    15181 tacatttcca tatagtgttg caaagatagc tgcaatgata attgaggaaa agtttgactt
    15241 gaaaatatgt gaccacgaaa taggatatat agcattacat tttggaagtt attttgaaaa
    15301 aaattcaaga aaagttctaa atgtaaatag ggtagctgtt gtttgtggaa caggtcttgg
    15361 gactgcacaa cttattagaa taaagatagg aaaaatactt ggagaaagtg tagaagtaaa
    15421 tactttttct gatatagaag ctaaagctaa tttagattta ttaaagtatt atgatttagt
    15481 atttacaaca gtagatttca aaacagactt agatgttcca atttttagag taaatgcgtt
    15541 atttaatgaa gaaagtataa agaaagagat agaaaatgca atacttttga aaaatagtat
    15601 aaatcttaag tctataaaaa agattgaaaa aaatatccct tttataggta aattaattga
    15661 agaggataag ttctttatat tgaataagag tacgtttatg gaaaatttag aagatatgtt
    15721 agaaaaatta gttcataaag gaattattga tatagagttc aaaaaaaagg tattaaaaag
    15781 agaaaagaaa tcttcaacag cattagataa ttatatagca ttgcctcact cagttaatac
    15841 taatggggaa aatctttatc tgtcatttgg aatattagaa aaaccagtgg tttgggatac
    15901 aaaggaaatt agaataataa tattgatgat aattccagat aagaatgtag atagtacaga
    15961 cctgataata aaaagttatg aagaagtact tgaagtaggg agagataaaa aaatgataga
    16021 agaacttgct aaagtaaaat catttgatga attttataaa ataattacca agaggaggta
    16081 ataatatgga cccagtaatt tttattatag catcacttat tacagtgtat ttattaaata
    16141 tttttcttgg atacttacag cttaaagatt ttaataaaaa ttatattgaa ctaaaaagaa
    16201 aaggaagagt ggcaataggc agaaaaaaag gaagaatttc atcaggtaca attgtgttga
    16261 tacttataaa tgatgatggt gtgattgtcg aaactagaaa aatgcaaggt gttacagtat
    16321 tggcaagagt aaagtcattt gaaggtttgg taggaaagag cttagagtac atagaaaaat
    16381 cagatttaac tgtttacaat aaactactta aaaaagcaat actagatgca gtcaaacagt
    16441 acataacatt tgagaaaaat aaatgtgaag atacaaataa tctgagtact gatgaagagt
    16501 gtaggatgga agtagtttaa aaaaatatat ttataaggag gagttaatat gacgcaattt
    16561 tttcaagtat tagcaagtgg tgcagatagt tttatgaatt tatttagggc aggtgggcaa
    16621 caatttgtag gttttgtaac agatatagta ccacttttag tagcattatt agttacaatg
    16681 aatgcaatta tcaactttat tggtacagat agagtcgaga gacttgcaaa aaaatgttct
    16741 gcaaatatat ttactagata tttgatatta ccagtccttg gtacatttgt atttgcaaac
    16801 ccaatgacac tatcactagg aagattcttg ccagaaaagt ttaaacctag ttactttgca
    16861 gcagcaagct tttcatgcca tacaatgaat ggattattcc cacatatcaa tccaggtgaa
    16921 ctatttatat atctaggaat tgcaaatggt ataacaactt tgggattctc aacagcagat
    16981 ttagcagtta gatatttgtt agtgggtata gttgcaaact ttattaaagg tgtagttact
    17041 gactatacaa caaaatttgt agagaaacaa caaggaatag cattaaattc agatataaag
    17101 attggataat tactttaagg tataaataaa tttttcaaat aaaaagatag tgtatagagg
    17161 aggataaatt atatggcatt taacaaagtt aaaatagtaa aaggttctgg aggatggggt
    17221 ggaccattga taatagaacc aacagaaaag aagaataagg tagtatatgt gactggggga
    17281 gcaaagccag aaactgcagt aaaaatagct gaacttacag gatgtgagtt aatagatgga
    17341 ttttcacagg gtgttaaaga tgatgaaatc gcatgtgtaa taataaattg tggtggaaca
    17401 ttgagatgtg gtatatatcc tcaaaagaaa ataccgacta taaatataat gaaaacagga
    17461 aaaagtggac cattagcaat gtttataaaa gaagatatat atgtttcagg ggtaaaacca
    17521 acaaatgtag agcagttata attgaggtag taggagggaa gaaatatggc ttatgatact
    17581 aaaaagaaga taagtgagca gagtcaagga attgttgcaa aaataggtat agcactagga
    17641 aatgtgacaa gtactctttt tcaagctggt agggatacta tagatacatt aatacatact
    17701 atactgcctt ttatggcttt cgttgcagtc ctaataggta taataaatca atcaggtata
    17761 ggaaattggg tagccaattt acttactcca ttaatcggaa atgttggagg tttagttgtc
    17821 ttatcaataa tatgttcatt tccgttgttg tctccgtttc ttggaccagg agctgttata
    17881 gctcagatag tgggggtatt ggttggtaca gaaataggaa aaggaaatat tccaccaagt
    17941 ttagcattac cagcattgtt tgcaataaac tcacaagcag cttgtgactt tataccagta
    18001 ggtcttggtc ttgcagaagc tgaacctgat acagttcaag taggagttcc gtcagtttta
    18061 tattctagat ttttaacagg tgcaccaact gttctattag catggttagc aagctttggg
    18121 ttatataaat agaagaatac tttataaata attagagaga ggttcagttg atatggaatt
    18181 aatatacagt actcaaataa ataaaatagg agataatgca aatgaatttt tacaacataa
    18241 tatgtttgta actttcaaag ataatgctcc tcaagagtta gaaaattact gttatataca
    18301 ttctgaaaat aatttagtaa aagaaatact tacgaatgat gtgttatcaa taaataatgt
    18361 tgattacaaa attacttctg ttggtgagtt agtaaaccaa aatctttcag aattaggtca
    18421 tataacattt aagtttacag gtgaaaaaga tggagcaatt ggagggacct tatatcttga
    18481 agaaaaagaa atagcaccta ttggcgtagg tactatacta aaaataatta gaaaataaaa
    18541 tttaaaacga atctaatcat attataagta aattatagat aaaagtcaat ttaactaatc
    18601 aagttaactt ttaatgtgat aaaaaagggg aaatgaaaat gagaaaagtg gctttagttg
    18661 ttggaggagg aagaagttta ggtgaatatt tatctaaaca tttagctaaa gtaggttatg
    18721 atgttgctat tgcagattta aatgaagaca acgcaaaaaa agtagctgaa gaaatagaaa
    18781 ctgaatttgg ttgtaaatct gtaggatatg gttgtaatgc catagatgaa agacaggtta
    18841 taagcactgt taaagctatt gaaaatgatt ttgatagaat agatttatta gtgtacaatg
    18901 caggagtggc tgtaagtaaa aaaataactg attttggata caaagatttt aaatttattg
    18961 tagacgtaaa tttaaatggg tactttctat ttgcaagaga agtatctaaa gtcatgatag
    19021 caaaaggtat tgagggtaga atcatacaga taaattcaaa atcaggtaga gtgggaagca
    19081 agcataattc aggatattca gcaggtaaat ttgctggagt aggacttact caaagtttag
    19141 cgctagattt ggcagaacat aagataactg taaatgcact gatgctcggt aatttacttg
    19201 attctgatat gtttgaaagt ttaattcctc aatatgcagt aaaattggga atacctgaat
    19261 cagaagtcaa gcaagtttat atagataaag tacctttaaa aagagggtgt agatttatag
    19321 atgttgcaaa tatgcttaca ttttatgctt caaaggaagc tgaatactgt actggtcaat
    19381 ctataaatat tactggtgga caagttatgt aaggttttta tggagtgtct caagatgaac
    19441 tctttagttc atgaggcact ttttttgtat aaaattaaat atattttcat catttaaaca
    19501 atgaaaaaga ggtttatctt tattttgaga tagcctcatt tttgtaatta agaaacatag
    19561 tgtttaagta aacatataag attgttagtt ttttaaaaga gaatttttta ataatattat
    19621 atttatgaag tatttttaaa ctt
//
LOCUS       DAEQJM010000067        19519 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.067, whole genome shotgun sequence.
ACCESSION   DAEQJM010000067 DAEQJM010000000
VERSION     DAEQJM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19519
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.067"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            314..1687
                     /locus_tag="KRQ43_002954"
     CDS             314..1687
                     /locus_tag="KRQ43_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2743298.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILANSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIEKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDILLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEGKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            1943..3010
                     /locus_tag="KRQ43_002955"
     CDS             1943..3010
                     /locus_tag="KRQ43_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBH2743299.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGDVLIEMEHPQQIIPEVE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            3107..3415
                     /locus_tag="KRQ43_002956"
     CDS             3107..3415
                     /locus_tag="KRQ43_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBH2743300.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKVNPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            3408..4838
                     /locus_tag="KRQ43_002957"
     CDS             3408..4838
                     /locus_tag="KRQ43_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBH2743301.1"
                     /translation="MNNSTSIKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGAKIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            4916..5290
                     /locus_tag="KRQ43_002958"
     CDS             4916..5290
                     /locus_tag="KRQ43_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBH2743302.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWNLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            5284..7488
                     /locus_tag="KRQ43_002959"
     CDS             5284..7488
                     /locus_tag="KRQ43_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH2743303.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLRIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            7488..8897
                     /locus_tag="KRQ43_002960"
     CDS             7488..8897
                     /locus_tag="KRQ43_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBH2743304.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELYIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            8882..9946
                     /locus_tag="KRQ43_002961"
     CDS             8882..9946
                     /locus_tag="KRQ43_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBH2743305.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERSIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKKLQDINLPKILIRIPMLSELEEVINYCDISFNSELETI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            9976..11397
                     /gene="nhaC"
                     /locus_tag="KRQ43_002962"
     CDS             9976..11397
                     /gene="nhaC"
                     /locus_tag="KRQ43_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH2743306.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            11826..12290
                     /locus_tag="KRQ43_002963"
     CDS             11826..12290
                     /locus_tag="KRQ43_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH2743307.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            12588..12950
                     /locus_tag="KRQ43_002964"
     CDS             12588..12950
                     /locus_tag="KRQ43_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH2743308.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            13545..14405
                     /locus_tag="KRQ43_002965"
     CDS             13545..14405
                     /locus_tag="KRQ43_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743309.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIIANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            14663..16777
                     /locus_tag="KRQ43_002966"
     CDS             14663..16777
                     /locus_tag="KRQ43_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2743310.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEHDVELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYVGTLTQLISM"
     gene            complement(17039..19282)
                     /locus_tag="KRQ43_002967"
     CDS             complement(17039..19282)
                     /locus_tag="KRQ43_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH2743311.1"
                     /translation="MSNIIIKGLTQNNLKNISFKIPKNKIVVFTGVSGSGKSSIVFDT
                     IAAESQRQMNETYSSFIRNRLPKYRKPQVELIDNLTASVIVDQTPLGGNARSTVGTIS
                     DLYSSLRLLFSRIGEPYIGTTSYFSFNDPNGMCKNCSGIGRVKVINIESIINPENSWN
                     TGCINDSLFKPNSWYWKQYAESGLFDLDKPIKDYSFEEYNLLLYGSKNKDGKQENPKI
                     EGIFNKYNQTYLNRDISNMSKHTKEKSERLITDKECPVCHGKRLNKETLNCNILGYSI
                     ADMCNMELTDLYDLLLQIKDKRTETVIKTLTDGLKRMIDIGLPYLHLNRESSSLSGGE
                     AQRLKLVRYMGSSLTGMTYIFDEPSAGMHPRDVHRMNQLLKKLRDRGNTVLVVEHDKD
                     VISIADEVIDIGPSAGTQGGHVVFQGSYDKLLLANTLTSNAMNLSLPIKTDSRHPKGT
                     LPIRDACINNLKHIDVDLPVGIMTVVTGVAGSGKSTLISRVFAQKYEKDVIKIDQSPV
                     TATNRSMPATFLGFFDEIRKVFAKENNVEEGLFSFNSKGACPVCDGKGVLVTELVFMD
                     PIINTCEACKGTRYSEEVLSKLYKGKCIVDVLSMTVDESLEFFTEKKLCKILQTMKDV
                     GLPYMTLGQPLSTLSGGERQRIKLAKNLNKKGTIYILDEPTTGLHGSDIEKLMLIFEH
                     IVDKGNTVIIIEHNLDVLKQADWVIDIGPDGGKNGGQVVFEGTPLEMFERGCTITSDF
                     LRKSINI"
BASE COUNT         7564 a         2280 c         3503 g         6172 t
ORIGIN      
        1 gttaatttat tgttttttta tatttgagag attacaactt attagtttgt atatctcttt
       61 ttttaataaa atcaataata tataaaacta ttggcatatt taatgacaat tcaaatattg
      121 tatataacca taatgaaaga tatataaata aaattttaaa tatacttaaa aatatattaa
      181 tataatgtac ataaaaaata tcataaatat atgataagat aaatacaata gcaatatttt
      241 attaattttt tgggttttta tatatttagg tactggggtg atatagttga accaagagat
      301 attttttaaa ataatgaatg aaatattgga aaatattgat gaaggggtac attttgttaa
      361 taaagacggg aaaactataa tctacaataa ttctgtacaa aaaatggaaa aaatgaacag
      421 acacgatatt ttagccaatt cattttttga tatagtcaac aaaatgaaaa taaacaggag
      481 tacactatta gaagttttgg aaaaaaggga agttatcaaa gacaatattc aaaaatatct
      541 ggacaaaaat ggaaaagaga taacagcaat taatactaca ataccaattg atattaaagg
      601 cgagtttgta ggggcacttg aaatatcaaa gaatatgaca acgatagaaa atttactaaa
      661 cagaaattat aaaaaaaatt tagtcaataa agttagtagt agacaaaaaa agggttatga
      721 atttgatgat attttagggg aaagtaattt gattaaagaa gcaatagaaa aatctaagaa
      781 agcttgcaag tctgatgctt cagtatttat atacggtgaa actggaacgg gtaaagagtt
      841 atttagccag tccattcatt atggaagtaa taggagaaac tatccattta tagcacaaaa
      901 ttgtgcggct ttgccggaat cactattcga aggtatcctt tttggaacta gcaagggagg
      961 atttacagga gcaatagata ggccaggctt atttgaacaa gctaacaaag ggacattgtt
     1021 attggatgag ataaattcca tgcctattat gttacaggct aaactattaa gggttttaca
     1081 agaaggttat gtaagaaggg ttggaggaac taaggatata cctatagatg taagaattat
     1141 tgcaacgaca aatgaaagtc caaaggtaat tttaaacgag cataaaatgc gaaaagattt
     1201 atattatagg cttaacataa ttcatataaa aattcctcct cttagagata gaaaagagga
     1261 catacttcta ttgtgcaaaa aatttatttc aaagtataat aaaaagttaa ataaaaaagt
     1321 ggtaggaatt tcagatgaag ctattaaaat tttaaaaaat tacgattggc aaggtaacat
     1381 aagagagcta gaaaacataa tttattgtac tatgagtatg atggaagatg aggtacaaat
     1441 agaaacaagt atgattaatc taaacgacta ttacaatctt aaagagaata aagagagtaa
     1501 caattattct ttaaacgatt tggagggcaa aacacttagt aagattatca gtgagataga
     1561 agaaaagtat atatatgaat cattagaaaa ggcatcgtac aatataacta aagctgcatc
     1621 aattttaggt atgaataggc aaaatttaca gtataaaata aaaaaatata atatcaaaat
     1681 attataaata agcaagataa aaaaacaaaa tagaagtaaa ataaaaaagc aaaatatagg
     1741 agcaaaatta ttataaaaga gcaaaatatt ttgctctttt ttttatttct cataagaaat
     1801 attatttttt atttatgaaa atacataata aaataattat agtttcaacg ttccaataaa
     1861 tatttacttt aattttaaag ttggcacgat ttatgcttta actaattatt gagaatatat
     1921 aaatttttag gagggtgtat atatgagaaa agtaagagta ggaatatggg gatttggagc
     1981 tatgggaata ggtatggcta atatgattct aaagaaagaa ggtatagaaa tagtatctgt
     2041 ttgtagtaga agtacttcag ggaaaagtat gtatgatgtt ttaggaattg aaagaggaga
     2101 aagaccagaa gttattatca ataaaaatta tgaagaagtt tttagagaaa aaagtgtaga
     2161 tgttgttttg ttagcaactg attcatttac taaaaaggct tttgataaaa taattttctt
     2221 attaaataga aaaataaatg ttatatcaac agcagaacaa atggcatatc cacaagctga
     2281 tgatgcagat ttagctaaaa aaatggatga agttgcaaag gaaaatggag taagtatact
     2341 tggaacagga ataaatccag gatttgtatt agatttacta gtattggcac tttcaggtac
     2401 ttgtgaagaa gttactagta taaaagctaa gagagtaaat gatttatctc catttggaaa
     2461 atctgttatg gaggaacaag gtgttggagt aacaagggaa gaatttataa aaggtgtaga
     2521 agataagact atagcaggtc atgtaggttt tgtagaatca ataaatatga tagctgatgg
     2581 attaggttgg aaattagata agatagaaca aacaaaagag ccaataatga ctacagtaga
     2641 tagaaaatct aaatacggag aggcattggc tggaaatgtt gctggttgta gacaatgtgg
     2701 atatggatat gtaaatggag acgttttaat tgaaatggag catccacaac agataatacc
     2761 agaagtagaa ggtattaaaa caggagacta tgtatcaata aaaggtatac caaacattga
     2821 tttacaaata aatcctgaaa tacctggagg agtaggtact tatgcaatga tagtaaactc
     2881 tattccatta ataataaatg ctagaccagg tcttaaaact atgttggata taccagtgcc
     2941 tagagcaata atgggagaca taagaaatca gatagaagtt gaattggaag aagaatcaaa
     3001 ggctaattag taagataaca gttagctaat tggtaaaata atgtttaatt taaaataaca
     3061 gtaaattaat tagtaaggaa tagtcaatta ataaggggat gaaaaaatgg atgctaaaat
     3121 taatgattgg gttattatac acaatatagt attgactcca gaagaaagag ctccacaagt
     3181 tccagaggat actaagaaag tatccttaga aatgtgggtt aaaggtttta tacaaagtga
     3241 tgcttctata ggcgacttag tagaagttaa aacaattaca ggtagacttg taaaaggtaa
     3301 tttacttaaa gtaaatccat attatactca tgattatggt aaatgtatac cagagttact
     3361 ccaaatagga atccaagcta aagaaatatt atttggaggt gtatataatg aataattcaa
     3421 catcaataaa agatatgagt tatcaagctg ttatgggaag aaataacgaa ataatgaaaa
     3481 atgcaatcgg attggattat tcttcttttg aacaagaggg aatagggttt gattatgaga
     3541 aaatgatgag tgaaacagga tatacattac aagatattga agcaattcaa tcacagtatg
     3601 ctgttggaaa tactcctcta atagagctta aaaatttgac taaattagct agaaaatgtg
     3661 ctaaagaagg taaaggagct aaaatatttg taaaagatga agcaatgaat gcatctggta
     3721 gttttaaagc aagaagagca gctactgcag tatatcatgc caaacaaatg ggatataaag
     3781 gtgtaatagc agctaccagt ggtaactatg gtgcagctgt agcatcacaa gcggcaatgc
     3841 agggattaaa atgtataata gttcaagaat gttatgattc taatggtgta ggtcaacctg
     3901 aaattataga aaaagcacga aaatgtgagg catatggagc agaagttgtt cagttaactg
     3961 ttggaccaga gttattttat acgttcttag ttttattaga agaaacaggc tattttaacg
     4021 catcattata ttcaccattt ggaattgcag gtgtagaaac tttaggttat gagttagcta
     4081 tccaatttag agaaaagtat aaaaaagacc ctgatatagt tgtttgtaca aatgcaggtg
     4141 gtggtaatct tactggaact gcaagaggat tgataaaagc tggttccatt aatactaaag
     4201 tagtaggagc aagtgtagat ttaaaaggat tacacatggc tagtgataat caatttaata
     4261 aaaaatcatt tacaacagga catacaggtt ttgggatacc atactgtaca tggcctgata
     4321 ggtcagatgt acctaggtct gcagctagac cacttagata tatggataga tatgtattag
     4381 taaaacaagg agaagttttt tatacaactg aattattggc acagctagaa ggtatagaaa
     4441 gaggtccagc aggaaataca tctttagcag cagcattctc tttagctcaa gagttagatg
     4501 aggataaagt tatagtggta caagaaacag aatatacagg cgcaggtaaa catatatgtc
     4561 cacagcttac ttttgcaaga gaaaatggaa tagatataaa atttggaaat ccaagagaag
     4621 aaattgcagg agtaaactta atattaccag aaagaccaga attattgaaa tgtgttgata
     4681 ttgatatgaa taaaataaga aagtcattta taaaaaattg catatctaat aatcacattg
     4741 ataatattga taagctaagt aatcgagata tagaattttt aatggaagaa gtaaaaagtt
     4801 caagagattt tgttgttgat gtattaaata atttatagta attattgttt ttttatttaa
     4861 tataaaataa aaattcggaa aattctatta aatcaatgcg aatggaggaa tgttcatgaa
     4921 aaaaagagag gatgattttg aagttagaag aaaacatctt caagaactga gtgatgatga
     4981 gttaaaagaa aggttttgga atttagctac ccagatagta gaaccaatga tagaacttgg
     5041 taaaaagaat acaacaccat caatagaaag gtctgtcttg ttgagaatgg gattttcttc
     5101 tcttgaagta aaacctattt tagaaggggt tatggaaaga ggtcttatag gtaaaggagc
     5161 agggcatgta gtttataaat tggctaaatc taaaaatata acggttagag aagcaggttt
     5221 gttattagtt aagggtgaat attgggatga agttacatgt ttatttagag aaggggtaga
     5281 atcatgttaa aggaaaataa aaaattggat atagactata tattaaaaga tttggataaa
     5341 tataaaccaa aacgaagagg ttgggtttgg agagaacact tggaaaatct tgaaatggga
     5401 ccttttaaat ataaagactg tacaaaacct ttaaagaaga gtgtagggct accatcatct
     5461 aagtatttca ataatataga ccctcaacca agtccagtta ttactactga aatagcttct
     5521 ggtagatttg aggatgatat aagaagaatg agaatggcag ctcatcatgg agctgaccat
     5581 ctaatggtta tcagaactgc tggacaatca cattttgatg ggcttataga aggaactcca
     5641 caaggtatag gtggagttcc aataacaaga aaacaagtaa gagctcaaag gaaggctctt
     5701 gattttatag aagaagaagt tggtagacct attaattacc attcatatgt aagtggtgtt
     5761 gctggtcctg aagtagcagt aatgtttgct gaggaaggag tcaatggagc acatcaagac
     5821 ccacaatata atgttctgta taggaatata aacatggtaa ggtcttttgt agatgcttgt
     5881 gaggcaaaga aaataatggc ttttgccaat atagctcaaa ttgatggagc acataatgct
     5941 aatgctactg ctagagaagc atggaaggta atgcctgaac ttatggttca acacgcttta
     6001 aactctatat tctcagaaaa aataggtata gataaaagta atatatgctt atcaacagtt
     6061 ccaccaacag cacctccagc accatgttta agaatagact taccttacgc tgttgcactt
     6121 agagaattat ttagtgatta taagatgaga gctcaaatga atactaaata tatggaatca
     6181 tcaactagag aagcaacagt tactcatgta ttaaacttat taacatcagt attaactaga
     6241 gctgacatac aatcaactat aacacctgat gaaggtagaa atgtaccttg gcatatatac
     6301 aatatagaag catgtgatac agcaaagcaa gctttagttg gtatggatgg gcttatggat
     6361 atgatagaac ttaaagatgt cggtgaatta agagacaaag caagagaact taaagaaaga
     6421 gctgtattat atatggaaga aatatctgaa gttggtggat attttgaatc tgtggaacaa
     6481 ggattttttg ttgattctgg aaattatcca gaaagaaatg gtgatggaat atctagaaaa
     6541 ataaaaggtg gagttggtga aggtactgtt tatgaaagag aagaagatta tttagcacct
     6601 gtaactgctc actttggata caataatgta gctcaatatg atgaaaatgc tatagataat
     6661 ccatcaatgt taatagatgg atgtacattt gaaaatccag acaaaataat atatattgat
     6721 gagcttgacg attttgataa tgtagaaaat agactaaaag aatcatatga gtacagaaat
     6781 ggaactaaaa ttaagcctga aatggaatgg tgtgcagatg gaattgtaat gataacaatg
     6841 atgcttccta ctgataaaag aacagcagag tttgcagctt tggaatttgt caaaaaaatg
     6901 aacttacaag aaattgaggt cataagtaga gaagttatgc atgaatctga agggactaga
     6961 atagaagtga aaggaagagt tccgtttgat atagatttaa acaatttagt aataccagaa
     7021 gaacctaagg tactaactga tgaagaaata agagcagata tagaagaaaa acctatgaaa
     7081 atagtttcag ctacggttgg agaagatgaa cattcagttg gtttaagaga aataatagat
     7141 ataaaacatg gaggtattga aaaatatggc atagaatgcc actatctagg gacttctgta
     7201 cctgtagaaa aattggtaga tgcagcgatt gaactgaatg cagatgcaat acttgcatct
     7261 acaataataa gtcatgatga tattcactat aaaaacatga aaaaattaca cgattattgt
     7321 gtagaaaaag gtataagaga taaagtaatg attgcgtgtg gaggaacaca agtaacacct
     7381 gaaatagctg ttgaacaagg catcgatgct ggatttggaa gaaacagcaa aggcatacat
     7441 gtagccactt tcttagttga aaaaagaaga gaaatgagta ataaataatg gaaaatagca
     7501 aagtttcttt aaaaatagat gtgttggtag ctgaaattgg aagtactact acagtggtaa
     7561 acgctttcca cgatattaat actaacaatc ctatattttt gggtcaaggt caagctccaa
     7621 caacagtgtt tgaaggtggc gatgtaagaa atggcttatc aggtgctatt aaagatttag
     7681 ctaataaatt atctgtagat gatatagagt ataatgatat gtttgcaact tctagtgcag
     7741 ctggtggatt aaaaatgact gttcatggat tagtctatga tatgacagta aaagcagcta
     7801 aagaagcagc tttaggggct ggagctgtta ttcgtcaaat aacatcaggt agaattaaaa
     7861 gaactgattt aaataaaata aaagaaataa acccaaacat aattttaata gctggtggag
     7921 tcgattatgg agaaagagat acagctattt ataatgcaga aatgatagct tctatgaatc
     7981 taggcatacc agttatatat gctggtaatg ttgaaaatca agaggaaata aggttaatat
     8041 ttgaagatac taattataag ctttatataa ctgaaaatgt ataccctaaa atagatttat
     8101 tgaatataga acctacaaga agaatcattc aaagtgtatt tgaagaacac ataactacag
     8161 caccaggaat gaaatacatt aaagaaatgg ttaatgaaaa tattactcca accccaggag
     8221 ctgtaatgga agcttctaaa cttttatata aaaatattgg agatttatta actttggatg
     8281 taggtggagc aactactgat gtacattctg ttacagatgg aagtgactat attaataaaa
     8341 ttttggttaa tcctgaacct actgcaaaga gaagtgttga gggggattta ggtgtatatg
     8401 taaatatgaa gaatatagta gaagttatag gtaaagaaaa cttacaaagt gaactatata
     8461 tagatattga tgcagtaata gagaattatc ctccaatacc aaaatcaaaa gaagaaatat
     8521 tatttgttga gaggttgaca aaagaagctg ttgttaaagc tatgctaaga cattcaggaa
     8581 aaataagaaa tatctatgga acaactggaa aagtcaaaat tgcagaaggg aaagatttaa
     8641 cagaagtaag atatatagtt ggtacagggg gagcacttac taggctccct agtagaattg
     8701 aaatattaga taatatgctc aaatacaata aaaataatga attactattt ccaaaggaaa
     8761 aaacaaagat attaatagat aatgactata ttatggcatc tatgggtgtt ttatctaaaa
     8821 aatatgaaga agcatctctt aagctcctgt taaaaagttt gaattttgag gaggaaagat
     8881 tatgtatcct aggttagaaa tagatataga aaagttaaag cataatgcaa aattaatttc
     8941 gcagatgtgt catgaaagaa gtattaagat atcttttgtt actaaatcat tttgtgcaca
     9001 aaaagaaata gtagaagaaa tatgtagtga aggaatagac catatagcag attcaagaat
     9061 acaaaactta aaaaaattac aagatataaa tctacctaag atattgatta gaatcccaat
     9121 gttaagtgaa ttagaagaag ttatcaatta ttgcgatatt agttttaact cagaattaga
     9181 aacaataaag aaattaaatg aattatgtga aagtaaaaat attattcata agatagttct
     9241 tatgtttgac ttaggcgatt tacgagaagg atacttttat gaagaagact tttttaataa
     9301 tgtaagagag atagtaagat taaaaaatat tgaaataatt ggtatagcta caaacttaac
     9361 ctgttatgga gctattatac catctaggga aaatataggc agactggtaa gtatagcaaa
     9421 aagaatggaa gaaaaatttg gaataaatct agaaatagta tctggaggta attcaagttc
     9481 tattcatctg ttgataaata ataatatgcc agaaggtatt actaatttga gaataggcga
     9541 gtccattcta cttggtagag aaacggcata cggtgaaaat ataaatggaa catatcaaga
     9601 tgcatttaaa ttaatatgcc aagtagttga atgtaaagaa aaaccatcag ttcctattgg
     9661 agaaatagga gttgatgcct ttagaaataa acctgtttat gaagataagg gaatcttaaa
     9721 aagggcaatc atagctatag gtaaacaaga tataaatatt gactctttaa ttccaataga
     9781 cactgatata aaaatattag gggcaagttc agaccacatg atactagatg taagtaacac
     9841 aaaatatgat tataaattag gtgacaattt agaattttta ttaacttatg ggggtatcat
     9901 gtcatctagt acaagcaaat atgtttcaaa aaaaattata gtgtagtgtt taaataatta
     9961 ggaggaaact attttatgaa agagcgagaa tgtagaaaag caagtctgtt tgatgcaatg
    10021 ataccaatta cttgtttgat attattttta agtctaggag tattagtgta tggttcatca
    10081 cctcatgtac cactaatagg agcagcagca gtagcaggac ttgtggctgt atatagactt
    10141 ggatttaaat ggaaagagtt agaattaagt atgtttaata gtataaagat ggcaatgcaa
    10201 gcaatcttaa tcataattat aataggcgta cttataggaa cttggatagt aagtggagta
    10261 gttccatgta tgatttactg gggactaaaa attttatcac caaatatttt tttagtagca
    10321 tcaacattag tctgtgcaat agtatctctt gcgacaggtt catcttggag cacaatgggt
    10381 acagtaggag tagctctttt aggaattggt caaagtttag gtatgccaat tggattaatc
    10441 gtaggttcta taatatctgg agcttacttt ggagataaac tatcaccttt atctgaaacg
    10501 actaacttag ctccagcaat ggcaggaaca gatttgttta cacatataaa atatatgtta
    10561 tattcgacta taccatcatt attaatttgt ttagtaattt atggtgtaat tggaatgaag
    10621 tattcaggtc aagcactaga tataaaacaa atagaattaa ttaggtctac attagattct
    10681 acatttaata ctttatcacc agtattatta ttagctccag caatagtaat tggattagtt
    10741 gtatttaaag ttcctgctat accagggctt atagtaggtg ctgtattggg agtattgttt
    10801 gcagtagttt ttcaaggaga atctatgaat acgatattag atgcagcaca aaatggatat
    10861 gtttcgtcaa cacaaataca ggaggtagat gctttattat ctaaaggtgg gattatgaat
    10921 atgatgtcca ctgtatcctt aacaatatgc gctttatctc ttggaggtat tttagaaaaa
    10981 acaggtatgc ttgaagtagt agcatcttct ttactaagat tagcaaaggg tgtatttgga
    11041 acagtattat gtactatggt aacttgtaca attaccaata taatagcagg tgaacaatat
    11101 ctatctatag ttataccagg aagaatgtat aataaggaat ataaaaagag aggtatacat
    11161 cctaagatgt tgtcgagagc tttagaagat agcggaactt taacttctcc attagtacca
    11221 tggaatacat gcggggcgta tataacagca acattaggtg tatctgcact aacatatggt
    11281 ccatacgctt tattaaatat tataaatcca atagtatctt tagtattaat tgcatgtaag
    11341 tttaaaatag caagaataga agatgaacct gaaacttgtt taaattttga tgtttgataa
    11401 tagataactt atgtaagaac gtaggaacta gggggggagc ctgtggggaa ttagtaagac
    11461 atattttagt gtgcgaaatt ctataaatca gtaatcttgt gactttagcc atgggaggtt
    11521 cagattagta aatttatagt tttatattag tctatacttt gatcttttaa ttgtttgtat
    11581 aaatttttta tagaaaaaga tttcttttag acttgcctaa aaattaggca agtcttttaa
    11641 gtatgttctg attataagag cactgtgtga caagaatgat gagattattt ttgctatact
    11701 ttcgatataa gaaatggaag gaggttatgt tttatattta tatgaaataa ttagttacac
    11761 agtgaatttt cgtataattt ggtataaaaa gattagaaat gaaaataaag taatggagga
    11821 ataaaatgac tagaatatcc aatataacaa tagctgaaca atctgagtac tgttttttgg
    11881 caatacgaaa aacaattgac tttatggtag agttttcaga gttttcaaaa caaagttttg
    11941 aaaaaatttc taaatatctg gaggagagag gaattttatc ttcaggagca ccgattgtat
    12001 gttttcataa catggattta gcaaaattgg atgttgaagt agggtttcct gtagccactt
    12061 atatagatgg gaaaaatgag attctacaaa ggattgttcc tgcacagaaa ataataactg
    12121 caattgattt aggaccttat gaattacaag accctacttt agaagactta ttttcatggg
    12181 caaatagcaa tggatataaa cttcatggcg atatatatta ccagtattta aatgatatca
    12241 atcgtccagc tagtgaatat cttacgaaaa tgatgttacc cattatatag aaagttaaag
    12301 attatcgttt gttagttgat aattagaaga acatttaatg ctactgcata aattttatcc
    12361 taaataatat caaggtgatt taatttatgt attctaatgt aactgtagat aatcaattta
    12421 taactaactt agtgtaattt agatttaatt tattattcta atgtaacccc aatatattgt
    12481 taaggtctac ttaagatgct caaaaggcta tgcttaattt attgttatat aatttgtaga
    12541 gtggtataat ttagaagtga tactatatag atatataggg ggaaaatatg aaaatatatg
    12601 atatattaac acgtttttat attcaagata tagaaaaagc catacctttt tatgagaatc
    12661 ttttaaaaga aaaatgttct ttgcgttttt cttataaaga agttgggttg gaattagcgc
    12721 aaataggaaa tgttttacta ttatctggtt ctgatgatgc tcttaaacca tttatagaaa
    12781 caaaatctac ttttatggtt gattctgttg atgaatggag aagttatcta ttggataatg
    12841 gagcagttgt agtaagagat aagaaaaaag ttcctacagg atataatatg acattgagac
    12901 atccagatgg tacaattata gaatatgttc aacatacaaa gcaggattag ttaaaaatag
    12961 attttactac tgagcaacta attagaatct attcttagac gtacaattta ttatttttgg
    13021 tattaataga ttataagtca aattataata tttcaaaata gaatagaaat ttatttacat
    13081 aaaagagagt gtttaaaaat gaacttttta gttcacgaag cactcctttt tgtatgaaat
    13141 caaatacatc aatatataaa acaaactgat gaagagctta aattaaaata aaaagattca
    13201 taacaggacc ccattaaact ttaagatagg gtaagtttgt aatcatatta aataattgta
    13261 aaaagctgtt tttagtcgta taatataaat atttatcatt taattaagga atctaaaagg
    13321 aatctaataa gaagaaaata ataaataact ttttagattt actaaatgaa aaattattga
    13381 aaattaaagg attagagtct ttaatcagaa agtaaaaagt aatatattaa atttatgaat
    13441 tgaaaactta aacaacaaat ttgtttataa aatagcaaga ttcattaaat ataactaagt
    13501 aataattgat ataatgttgc atggataaaa ggagggaagc tgcaatgtct tacaaagtaa
    13561 ttaatgtcat aactgctatt gactatatag aggagcattt atcagaaaag ctggatttag
    13621 atataattgc taatgctgtt cattactcaa aatatcacct gcatagaact ttcacaactt
    13681 ctgttggtct aacaatgcat gattacataa agcggagaaa gttgacagaa gcagcaaaat
    13741 tattggtatt ttcaaagaaa ccaattattg aaattgcatt gatagctgga tatgaaagtc
    13801 aacaggcatt cacttctata tttaaagcta tgtataaaaa atctccaaat aaatatagga
    13861 aagaacaaga attttatcct ttgcagctaa gatttgtttt gaaaaaagat aacctatttt
    13921 caaagaatgt actagagttg gaaaaagaaa ttaaacttgc aagtatgtct gacataccat
    13981 tatggatgaa tttagtgaga ttagtcatag atggatttcc aaatttgcaa gaggaagaat
    14041 atatatatca attagaacag tatattttag aagaaagagc tttaatatta aaacttaata
    14101 atgtcgctat tgcaaatatg gtgtttaata gagaaactag aagtattgat ttttttggaa
    14161 tacatccaca gtatcgtaat tcagacattg cacaagtgtt tttgaagaaa gttattgaag
    14221 atttcttgat agatacagat atctcaatta ctacctttcg agagggtgac aaagctgata
    14281 caggacatag agatatgata aagaagttgg ggtttgcaga agcagagttg cttgtggaat
    14341 ttggatatcc tactcaaaaa tttattcttc cttgtgtaga agaaagagat aatagacaaa
    14401 attaattgta gattaaatgc aaagtttacc acatattttt tgtttgaatt attttatata
    14461 taagagtatt tctgctttta atgtattttg cttgtaagtg tacttatggt aataaatata
    14521 gaaagattta gttttttaaa aaaagaactt taaagctaaa aagctaacat ttaagttaaa
    14581 tagcaagaat gattaaaaac tccaaaacac aattaagtat aatgattcag tgtaagtact
    14641 taattaacaa aggaggattt aaatgtctga aaataaacaa gtagtaaatt gcgatattat
    14701 tgcatccaat tctaaacata atatgtgtga acatgatgta gagttattaa ctttttttcc
    14761 agatgagatt gcacatctaa tagagataaa taacaagcta gacaatgctt ttaagaaagc
    14821 tgaaaatctt gttgacaagc ttgataagga ttatatggac gctaaaatgt atatggtaaa
    14881 aaatcgtggt gaaatagacc cacatgaaat gtttcaaaat gaacaaggac taaaacaaat
    14941 agataactat ggggctttta tggtaaaagt tcgagataag attaataaaa tcaaagattc
    15001 tccatacttt gctagaatag attttaggct gaaagatatg gatgatgaat ctaagtatta
    15061 tattggtaga tttgcatttg attatgaaga tgagcttata atacttgact ggcgttctcc
    15121 aattgccagt atgttttatg attatgaaat cggaaaagct ggatatgatg ctccaatagg
    15181 atgggtggat ggagaaataa caagaaaacg acaatttaaa attaaaaatg gaaaattgga
    15241 atatgcacta gaaagttcca ttaatataca agatgatatt cttcaaaaag aacttagtca
    15301 cacttcagat gaaaaaatga agtcaatcat ttcaacaata caaaaggaac aaaatcaaat
    15361 tattagaaat gataaagctg atacactgat tattcaaggg gtagctggtt ctgggaaaac
    15421 atctatagca ttacacagaa ttgcttttct tctttatcga tttaaagata aaatatcagc
    15481 aaataatgta attatcctat cacctaataa agtctttgga gactatattt ccaatgtcct
    15541 tcctgagctt ggagaagaac cattatgtga attaagtttt gaaaatatag cagaggtaca
    15601 attagataga gttattaatt ttgaaagtga gaaagaccca ttagaaataa atgatgctaa
    15661 atggtctgaa agagtgcgtt ttaaatctac acttgatttt gtaaaactta ttgatgatta
    15721 tataaaacaa atgccaaata agatttttat tccaaaagac tacacttttg gaagttttac
    15781 agctaaaagt gactggatac agagtagatt tgaggcatat aacagatatc cagttaagaa
    15841 gagattagaa aaggtagctg aagacattca ttataaattt gaatcagata atattatgga
    15901 agaagattta ccaaaggtaa aaagtatact taaaagtttg aatggaatgt tgacaataaa
    15961 aaatactctt acactatata aggatttctt taaacaaatg aatatatcaa acatgtttgt
    16021 gatggcagaa aagaaaacac ttgaatggtc agatgtatac ccatttatat atattcatgc
    16081 tgcatatgaa ggtatacaag aagataagat tataaggcat attgttattg atgaaatgca
    16141 ggactataca cctattcaat atgctgtaat aaacttactt tttaagtgta aaaagactat
    16201 tcttggagat tttggacaat tggttaatcc taatcatact catacattag atgatatgaa
    16261 acagctatat aatgatgggg aactagttat gttgaacaag agttaccgtt ctacttttga
    16321 gattattaat ttcgccaaaa agattcaaga tatatcttca ttagagccta ttgaacgaca
    16381 tggtgaagaa ccggctttat taaaatgtaa taacgagcaa gatgaaataa ataagataaa
    16441 aatagaaatt gaagaattta aaaagagtga taatgcgact cttggtatta tattaaagac
    16501 agataatgac gctaaagctg tatatgatgc gttaagagaa gaatatagtg ttcacttaat
    16561 atcttctgaa agttctagct ttacaaaagg agtatccata acttctatta aaatgtcaaa
    16621 aggtttagag tttgatgaag ttattgtacc ttcagtaaat aataaaacat attatagtga
    16681 ttatgaccgc agtttgttat atattgcttg tacacgagct atgcacaaac ttaagttaac
    16741 atatgttggt acattaactc aacttataag catgtagatt atatcttata tgcatttatt
    16801 atcgtaaata taaattggga caaagattca tcaataaatc aacaaaaaat aatacttata
    16861 aatttataaa aaatgaaagc tataaattac atttgaaatt ttataaaatt ttgtgattta
    16921 tagcttttat aatattaatt tcttttaaaa taaagttaaa ctttaaattt atgaaataaa
    16981 acaaagtagt aatatatatg taatagttct taatttttta atattagtat tatattatct
    17041 atatatttat tgattttcta aggaaatctg atgttatagt gcaacctctt tcaaacattt
    17101 ctagtggtgt accttcaaat acgacctgac caccgttttt gccaccatca ggaccaatat
    17161 caattaccca gtctgcttgt ttcaatacat ccaaattatg ttcaattata attacagtat
    17221 tacctttatc aactatatgc tcaaaaatca acataagctt ttcaatatca gaaccatgaa
    17281 gccctgtagt tggctcatct aaaatatata tagtaccttt tttgttgagg tttttagcta
    17341 acttaattcg ttgacgttct cctccagata gtgtgctaag tggttgacct aaggtcatat
    17401 aaggtaaacc aacatctttc attgtttgta agattttaca tagcttcttt tctgtaaaaa
    17461 attcaagaga ttcatctact gtcatagata gtacatcaac tatacattta cctttatata
    17521 attttgacaa aacttcttca ctatatctag tacctttgca agcttcacat gtattaataa
    17581 tagggtccat gaatacaagc tctgtaacaa gtactccttt accatcacaa acaggacaag
    17641 ctccctttga attaaagctg aataaacctt cttcaacatt attttcttta gcaaatactt
    17701 ttcttatctc atcaaagaaa ccaagaaatg tagcaggcat agaacgattt gtagctgtaa
    17761 ctgggctttg gtcgatttta ataacatctt tttcgtattt ttgtgcaaaa acacgagaga
    17821 ttaaagtact cttgccagaa cctgctactc cagtaacgac agtcataatt ccaactggta
    17881 aatctacatc aatatgtttt agattattta tgcaagcatc tctaattgga agggtacctt
    17941 ttggatgacg agagtcagtt tttataggta atgatagatt cattgcattt gaagtaagag
    18001 tgtttgctaa aagtaattta tcataagagc cttggaatac aacatgtcca ccctgagtac
    18061 cagcacttgg gccaatatct ataacttcat ctgctatgga gataacatct ttatcatgct
    18121 ctactacaag gacagtattt cctctatctc taagtttttt taatagctga ttcatacgat
    18181 gtacatctcg tggatgcata ccagcactag gttcatcgaa aatataagtc atacctgtga
    18241 gactgctccc catatagcgt acaagtttta atctttgagc ttctcctcca gatagagatg
    18301 atgattctct atttagatgt aggtaaggga gaccaatatc aatcattctt tttaaaccat
    18361 cagtaagagt ctttattaca gtttcagttc ttttatcttt tatttgtaac aataaatcat
    18421 aaaggtcagt aagttccata ttgcacatat ctgcaatcga atatcctaaa atattacagt
    18481 taagagtttc tttatttaat ctttttccat gacatacagg acattcctta tctgttataa
    18541 gtctttctga tttttctttt gtgtgtttgc tcatattgct aatatctcga tttagatatg
    18601 tttgattgta tttgttaaaa ataccctcta tttttggatt ttcttgtttt ccatctttat
    18661 tttttgaacc ataaagcaat aaattatatt cttcaaaaga ataatctttt ataggtttat
    18721 ctaaatcaaa aagtccagac tctgcatact gcttccagta ccatgaatta ggtttaaata
    18781 aagagtcatt tatacatcct gtattccatg aattttcagg atttataata gattcaatat
    18841 tgattacttt aactctacca atcccagaac aatttttaca cataccattt gggtcattaa
    18901 aagaaaaata tgaagttgtt cctatgtagg gttctccaat tctagaaaat aataatctta
    18961 atgatgaata caaatcactt atagtgccaa ctgtagaacg tgcattgcca ccaagaggag
    19021 tttggtctac gattacagaa gcagttaaat tatcaatcag ctccacctga ggttttctat
    19081 atttaggtag cctatttctg ataaatgaag aatatgtttc attcatctgc ctttgtgatt
    19141 ctgctgcaat tgtatcaaat acgatactgg attttccaga accagaaact ccagtaaaaa
    19201 caacaatttt atttttagga attttaaatg atatattttt taggttattt tgtgtaagtc
    19261 cttttattat aatatttgac atgaatgtta aatcctttct gagtacattt tagtaaagca
    19321 attatattat gtaaccatat tataataaaa ttaaaatcta ctttcttgat atattctgct
    19381 atgttataga aggtatttct aaatttaacc aatcccatac aatctgaata aatgatagtt
    19441 gataatagat aaaaaagtat ataatagata ctcgtaattt gataagtaca aagataatta
    19501 tacaattaaa acgacttga
//
LOCUS       DAEQJM010000068        18688 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.068, whole genome shotgun sequence.
ACCESSION   DAEQJM010000068 DAEQJM010000000
VERSION     DAEQJM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18688
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.068"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..413)
                     /locus_tag="KRQ43_002968"
     CDS             complement(<1..413)
                     /locus_tag="KRQ43_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH2743312.1"
                     /translation="MILVSACLIGINCKYSGDNNENEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKIKSEKDL"
     gene            complement(481..2859)
                     /locus_tag="KRQ43_002969"
     CDS             complement(481..2859)
                     /locus_tag="KRQ43_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH2743313.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSEISAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRNLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            3176..4627
                     /locus_tag="KRQ43_002970"
     CDS             3176..4627
                     /locus_tag="KRQ43_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HBH2743314.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(4831..7344)
                     /locus_tag="KRQ43_002971"
     CDS             complement(4831..7344)
                     /locus_tag="KRQ43_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH2743315.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTSDEQLEVLKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTDLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKDTEKLKVGVLLNKPPFQNADKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLEDMAKKHEIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLNGK
                     RIALAKGIDYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYEAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKSDKESENGNIENERDKIRREYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRITSKIIYNDRKIPMYVIGKIANIDSEKEEKNRLLDKVQR
                     DSLTNIYNAAYIRKLTTQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLVGDKVLIDV
                     AKVLDESFAKDDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVITKRGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(7567..8388)
                     /locus_tag="KRQ43_002972"
     CDS             complement(7567..8388)
                     /locus_tag="KRQ43_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH2743316.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMIVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEMR"
     gene            complement(8907..9383)
                     /locus_tag="KRQ43_002973"
     CDS             complement(8907..9383)
                     /locus_tag="KRQ43_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HBH2743317.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVGNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(9417..9995)
                     /locus_tag="KRQ43_002974"
     CDS             complement(9417..9995)
                     /locus_tag="KRQ43_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH2743318.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(10099..12717)
                     /locus_tag="KRQ43_002975"
     CDS             complement(10099..12717)
                     /locus_tag="KRQ43_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH2743319.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIETGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MNRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMASSISIDSSISIDSSISIDSSISMDLDTSSSLGIPKELMGSNTNNIDTLSNTSK
                     IDTLNKNHYNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFK
                     KKDLNIDCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGY
                     APMMVTEYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSK
                     VTCMLDNLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKK
                     LDEIGTVAGHYYKGVE"
     gene            complement(13209..13892)
                     /locus_tag="KRQ43_002976"
     CDS             complement(13209..13892)
                     /locus_tag="KRQ43_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBH2743320.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(14234..14824)
                     /gene="zapA"
                     /locus_tag="KRQ43_002977"
     CDS             complement(14234..14824)
                     /gene="zapA"
                     /locus_tag="KRQ43_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBH2743321.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDVYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(14849..17242)
                     /locus_tag="KRQ43_002978"
     CDS             complement(14849..17242)
                     /locus_tag="KRQ43_002978"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBH2743322.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(17259..18278)
                     /gene="pheS"
                     /locus_tag="KRQ43_002979"
     CDS             complement(17259..18278)
                     /gene="pheS"
                     /locus_tag="KRQ43_002979"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBH2743323.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(18328..18562)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         5765 a         3449 c         2050 g         7424 t
ORIGIN      
        1 tataaatctt tttcactctt aatttttatt ccttcttctt ctaacagcct tgctgttata
       61 cctttccctg gtatcttttt acctgaaaaa ctaccatcat atattagatt acatccacaa
      121 gaggggctac cctcttttag tattgcttcg ctacatacat ataaatttgc tatttttaga
      181 gtttcattag cccctcttac aaagttttct gttacatcct tattatcttt agtaattact
      241 tttccatcaa ctatctcagc aggtggtctt ggtgtagata gaccacctaa ctgctctggg
      301 catacaagtg taaattcttt gccttttaaa tattccttga ctttttcatt ttcattatta
      361 tcgccactat atttacaatt tattcctatt aaacatgcag ataccaatat cataaaaatg
      421 tgctcctata caaattctta atatattctt atacaaatta ctaatgtatt cttatacaaa
      481 ttattttaat ttaacaattg ttactcctgc tccaccttct ccatattgac cacctcgttg
      541 tgattttaca tgtctatttc ttcttaaaat gtcttgtagc cctgctttta atactcctgt
      601 gcctattcca tgtattactg ttacagactc taaacctgcc acatatgcat catcaagata
      661 cttttctact tccattatag cttcttctag gtttaaccct ctaaggtcaa cttcattttt
      721 tacactacca gattttgacc ttataatgtt tctcgttgat ttagttacat ttgttgaaac
      781 atctttgcgt gttttttgta aagatttaaa aggtagagtc atcttcatta taccaatttg
      841 cactactgct tcttttctct ttttatctac tgaaactaca ctaccatttt gatttaaagt
      901 tattacctta acttcttcac ctggctttaa gtcttttatc tccttatttg atacctttgg
      961 aactatcata ctttttactg ttggctgaag acttcccata gagctggtca attcttttct
     1021 aagttcttct atcttacgat tcttttcttt tgaagctctt tcttgttcaa gatttctaag
     1081 ttcttttatt ataatatcta cttcttcttt agcttgtctt ataattgaaa atgcttctga
     1141 tttagctttt tcaatcatct tatctctttg actgaccaat ttttcaagtt tttcgtcata
     1201 ctctactttc agtttttcaa tctcttcttt taatctttca gcttcttctc tatcttctac
     1261 tgctttgatt ctattctttt caacattctg taacacatct tctaaagcta tgttttctgt
     1321 atttatatat tctttagcac gtgaaatcac ataatcactt agcccaagtt ttctagaaat
     1381 ctcaaacgca tttgattttc cgggaacacc tataagtaac ttatatgttg ggcttaaagt
     1441 ttctatatca aattcaactg ctgcattttc tacacctggt ttagtaagag cataattttt
     1501 aagctcacta tagtgagtgg tagctataca tttagctcct acagaattta tatcttctaa
     1561 tactgctatt gcaagggcag ctccttcaac agggtctgtt cctgctccta actcgtcaaa
     1621 tataactaaa gagtctgctg ttacgttttg taatatagat actatattcg tcatatgaga
     1681 tgaaaatgtt gatagactct gttcaatact ctgttcatct cctatatctg caaatacatt
     1741 atcatataca cacatactac ttccataatc agcaggtata tgaagtccac tttgtgtcat
     1801 aagtgcaaat agacctacag tttttattgt aacagtctta ccacctgtgt ttggacctgt
     1861 tatcaccaat gtatggaagt ctcttcctaa ataaattgta tttgctacta ccttcttttt
     1921 atccagcagt ggatgtcttc cattttttat gtttaaatat ttatcctcat ttaaagttgg
     1981 ttctattcct ctcatctgta tagaaagttt tccctttgaa aatgcaaagt ccaatcttcc
     2041 aagtatctct tgattagaga ttaaatcttc gctcacttct ccaaccatag ctgaaatctc
     2101 tgataaaatt ctttctattt cctcttgctc tcctagtttc aactgcctca attcattgtt
     2161 catctctact atagtcattg gctctataaa aagtgtcgca ccagaagatg actggtcatg
     2221 cactatacca gctacttgcg acctatattc agattttaca ggtactacaa atctatcacc
     2281 tcttagagaa attattgcat cttgtaagta cttttgataa gtagttgaac ttattattga
     2341 atttaatttt gacctaatgg attgattttt ttgggctatt cttcttctga tatctctaag
     2401 tgtacttgaa gcattgtcag atatttctac ttcactaatt atagcattgt atatctggtc
     2461 ttctatgtcc ttgtacacat atagagaatt tgatagagat tgtattattg gataattaaa
     2521 atcttcttca tcactactag ataagctatt tcttaatctt ctagccactc ttaaggtatc
     2581 tgctatcata atcagacttc ctgggtcaag agaagcacct atataagctc tctttacctt
     2641 atcttctata tcatgaatac cttccaaccc tactgaacct ctctttataa taattgattg
     2701 agcttcacta gtttcttcta gcatagattt cacttctaca aaatcagtat ttggtactaa
     2761 attttctata tattttagac ctaaagaaga tgaggctttc ttctttaaca aatctattat
     2821 tttattgtat tctagaactc ttaacgattt ctcattcatt ttctatattc accatcctcg
     2881 atattttaac ttttttattt aattttaaaa atgtatgttt tcaagcattt ccaataaaaa
     2941 atgcaagttt tatttctttt tcatttctaa aattattata ttttttctct tttagatata
     3001 ttttacacat attttgtatt atactatgta tgtagctatc tatatattat acataaacat
     3061 gctttatttg taatataatc tgttaaaaaa tcttctttaa tatttttaaa ggagtttatt
     3121 ttagcttata aaaaaatagc tacttatata gataaattaa ggaggaacat gagtcatggg
     3181 aaacgtatta gaaggattaa aaccagaaag tgtttttaaa aactttgaga aaatatctca
     3241 aattcctaga ggttctggaa atgaaaaagg cataagtgat tttttactta gctttggtaa
     3301 aaatttaggt cttgaaacta ttcaggatga aagcttaaac ataataataa gaaagcctgc
     3361 tacaaaagga tatgaaaatt gtccaggtgt agttcttcaa ggacatatgg atatggtttg
     3421 cgaaaaagaa aagaatgttg aacatgattt tcttaaagac cctataaaat taagaattga
     3481 tggtgacatg atatatgcta ctggaactac tctaggagct gacaatggta tagctgttgc
     3541 tatgggtatg gctatattag aagataatac tttagagcat cctgcactag aagttttagt
     3601 tactgttaat gaagaagatg gtatgaatgg tgcagatgca ctagacccta gcttaattaa
     3661 aggtcaatat atcctaaata tggactccga ggaggaagga tacttattag ttagctgtgc
     3721 tggtggtaaa acttgtgttg ttagtttacc tgttgaatac aaggaagtta aaggtgacaa
     3781 acaaggatta ttagttgagg ttactggact attaggtgga cactctggta tggaaattgt
     3841 tttacaaaga gcaaatgcta acaaagcaat agctagagta ttaagtgtat tgaatgttga
     3901 ttatgaatta gcttctgttg atggtggtac taagcacaat gctatacctc gtgaagctaa
     3961 atgtgtaata gctgttaata aagctgatgt tgaatctgct aaaaaacaaa taaatgacat
     4021 tttaactgca tttaaacatg agtttactac ttctgaccct ggcatgactt actcagtagc
     4081 tgaaacttct gtagacaaag ttcttactaa agattgtaaa gaaaaagttg ttcaaatgtc
     4141 ttgcttaact cctcatggag ttcaatcagt aagtcttgat atagaaggat tagttgaaag
     4201 ttctactaac ttcgctataa ttgaaactaa agaatctact attgaatttt taacttctgt
     4261 tagaagttct gttatgtcta ttagagatga aatcgctgat agaataagac ttttggctca
     4321 agctttaggt gctaattacg accttatagc tcaataccca gcttgggaat ttaaaaaagg
     4381 ctcaaaatta gaaaaaatat gcagtgaaac ttatgagaaa ttaactggta aagttcctac
     4441 tgttatggct ctacatgctg gtcttgagtg tggattatta cttgataaac ttcctcatgc
     4501 tgaagctatc tctataggac cagatatgtt tgatgttcat actccaaatg aacatgttag
     4561 tatcccttct gtagctaatg tttgggatta tgttattgaa atattaaaat ctatgaacca
     4621 atattaaatt taagttttga ttctaaatag attttaattt taagtaatct atataaaatt
     4681 aactctgtaa attaatacta ctgttagtat aatatttact ttcaatatta acttatagaa
     4741 ataaagccta atgatagata ataacatgta tcattaggct ttattgtaat ttaaatatta
     4801 ttaaacttta ttctgtttta aaattaattc ttatactatt ttaaatctat ttcttccttg
     4861 tctcttagaa tcataaagag cattatctgc tatttgatac agttcatcat actcttgacc
     4921 acgctttgtt ataactaccc ccatactaat agataaactt tctccatttg gcaacttaat
     4981 gagatgaata tgattgtata catcattaca tttattgata agttcttcct tatttattat
     5041 atcatttata taaacactaa attcatctcc acctaaacga cctactatat catcttttgc
     5101 aaaactttca tcaagtacct ttgcaacatc aatcagtact ttatctccta ccaggtgacc
     5161 ataagtatca ttaattgact taaaataatc aatatctata atcaataaag ctccattttt
     5221 ttcagttgat aaatttaata aattttgtgt agttaatttt ctaatatatg ctgcattata
     5281 aatatttgtt aaactatccc tttgaacttt atccaacaat ctattctttt cctctttttc
     5341 agaatcaata ttagctattt taccaattac atacattggt atttttctat cattataaat
     5401 tatttttgaa gtaattctaa tccaatgaaa agtatcatca agcatgatag aatacatttc
     5461 agtagtccca ttttcttgtg attttattac atcaaaaaac tttttattat attctcttct
     5521 tattttatct ctttcatttt ctatattgcc attttcactt tccttatcac ttttatccaa
     5581 accataataa gtctcaatac ccttttctgg catagaaatt atcaatttat cttgcttata
     5641 atcatactca aaaaagtatt cacttgtcat ttcatacaac tgagtatgtt ttttgagttc
     5701 caaagatatc ttttcgttca tacttgtacg agtatgtaaa ccaaatgcca taaatccaat
     5761 aatacaaatt aataaacttg ctacaataaa aatagtctca attggattct gttgcataat
     5821 ataaagcaac gagaaatctt gtctatatgt agtattttgg tagacaattg attgcatttt
     5881 ttctgatgaa atacttataa tagctttatt aaatatattc aataattctt gtttatcttt
     5941 tttaattatg ccaaaacaaa tactctttgc ttcataagtt tgaggaacta ggcgcacatt
     6001 tttatactta ggttgattca tatagtactg catagaataa ccttctccat aagtgtaatc
     6061 tgcatagcct ttattaacag cttctataca ctcttctaaa ttatcatacc aaactatatt
     6121 ttcttcaaac tgaccataat aatcaatacc tttggctaga gctatacgct ttccatttag
     6181 actattctca tttaatttat tattaatcat catagtatat tgagtagaaa gaaaaggccg
     6241 agacatagct atattatgtt cacgagagta ctcataatca taaatcattc ctgctacaat
     6301 atcaatttca tgttttttag ccatatcttc caaatcttct tgagatttta caggcacaag
     6361 ttcaaattcc aaacctgttt tatcacatat atgatttaac aaatcaattg atatacctct
     6421 taattctcct gtatctttat ctgcattttg aaacggtggt ttgtttaaaa gtactcctac
     6481 ttttaatttt tctgtatctt taatgtaatt agtttcttca tcagataaaa acatttgatt
     6541 attctctggc gtaaagtatt tctcatataa agtagttgaa aaatatgggt ccttctgttc
     6601 aatattatta attgctgaat taagcttttg agttaagtct gtactgcctt ttggagtaat
     6661 gaaataaaat ggctttgatg agaattttgc tacagtacgc acaccttcta ttgggttcat
     6721 actaacatta agaagtacat ctgctttacc actctttagt acttctaatt gctcgtcact
     6781 tgttttacaa tataccaatt caggtgacat aagattcatt ttacaatact catctaattc
     6841 tttaagccta gtatcagaat tttctattac agcaatacga atttttttca catcttgcga
     6901 actcattatg ttatcaatat ctgtattttc atataatgct tgtagtactg tatttgctac
     6961 tccataactg tttcccgcat aattatatat tttttgcatt ggctcattgt ataacatacc
     7021 tcccattata tcaatttcac cattttctaa catcttcatt aattttgtaa tagattcatt
     7081 tatctctcca ggaacttgaa caaattcata attccatcca gtatactgtg caatttctag
     7141 caaatattca tatgtatacc caaaatagtt accttgctca tctatttcag ttaaaccttt
     7201 ttgaatagga taagcaacac gaatggtacg attatcatta cctatagcat tgataccaaa
     7261 agaaaatatg caagaagtga atatagatgt aattacaata attaataaaa gtaatttttt
     7321 taaattcact acacaatcct ccatatagtt aagatttaca gtataaatta ctgcataaac
     7381 ttgtagacat gaaaaaatag attagtatat aaaaggatat ataaatctac ttagaaattt
     7441 aaatatcctt aatatataca atatatttaa attataactc atttatatat ctattacaac
     7501 aaatttaccc tgctaaatac ctactctata tcccataatt ttacaagttg taatgaagtt
     7561 taagttctat ctcatttcaa atttagcagt gtttctattt acagttcttt tatatttcac
     7621 atctggataa cccaatataa atgaagtgat aactgcttcg ttctcgctca ttcctaacag
     7681 ttcttttatc tttggctcta catttgatgc cataacaaaa aatccattat aacaaattcc
     7741 taatccttga gaataggcca taagttccat attagatgca gccaatcctc catctacata
     7801 agcacttcca cctagagaca tatcacctac aactatcata agtagtgggg catcataaaa
     7861 taaagaatca tttccgttct ctttatatct tttgtacatt ttcttaaatg tatttttata
     7921 gatagaacgt acagggtcat tgtcatcagt atctaatgcc aaattataaa gaccttgtat
     7981 tgccagttct ttcacttctt ttagcttttc ttttactaat atgtatctta taggctgtct
     8041 attaccacct gttggtgtgt atctaccagc ttccactatg ttttttattt tttcttcttc
     8101 tacctctata tctttatatt gtcttatact tcttctaaat ttaataaaat tcaataactt
     8161 ttcgggttct aattcaaaac tttcacgatt gtattctatt acttcatttt tatcaaatcc
     8221 ttgcatttct attgcatctg ttgggcaaat tgccatacag tgaccacagt taatacagag
     8281 aatattttta acctttgctt tatcatcctt aacttttatt gcatttacaa gacagtctga
     8341 ttcacacatc ccacagccta cacatttttc taaatttatg tctatcattc caaattattc
     8401 ctccttttaa aaaatttact ttagtataaa acaaatagtt gtctaagtca atttttattt
     8461 ttttaacaat atactagcct taactacact ttaatggaga aaaatataca taaaattaga
     8521 acttaaatta gaatttattc aaaataaaag ataaaagaag taaatgtcta aaagtgaact
     8581 ttttagttaa tgagacattc tttattgtat gaaatcaagt ggatatttat catttcaaca
     8641 ataaaaaagg cttacctcta ttttggatat gtccttgtta agtagacaga ctaaaaaagg
     8701 ctatctttat gcactgagat agcccctttt cccaactact attgtttatt ttaatattat
     8761 atcaataaat ttaatttgct ataacctgta agttacattt taatttgatg taactttaaa
     8821 ttacattttt aagtaatatc tttaaattat attcttaaaa tatatcatta aactacattt
     8881 taattaatct aaaaactata tcttaattaa tctaagaaac ttacattata atcttttagt
     8941 ttcccattat catatacaat ctttgcacta aagatatttc cagtcttagc ccaatttaag
     9001 aacaacctgt caccttccca catatttaaa tcgaatattt tatcattacc aacccaaatt
     9061 aaatttcctt ctttacaatc atttaaatct ttttcagaca attcaccttc aaactcatct
     9121 gagaaataca aaaacatata ccaatcttct tcatctttaa attttggaaa agttatcaac
     9181 cctttatatg acaatgattt aagagtaaga ccagtctctt cctttacttc cctaattaca
     9241 cattcttctg gagtctctcc ttgctcaaac tttcctccaa ctcctacata cttaccttca
     9301 tgtatatcat ctttcttttt atttctgtac aacatcaaag tcttgtcatc tttttctata
     9361 taacaaatag ttgtaagttt catgtatctc gccttacttt ctctttatat tctcaattaa
     9421 ttattttcag cactttcaag cacatcactt atattcttca ttgcattaag agaaagttct
     9481 gcaaattcat caaatggaat ccctatatct tctatacttc tcattgcatc tctatttaca
     9541 tttgaagcaa atctcgtttc tttcattctt ttaataacag acttagtctt tacactagta
     9601 agttttttat ctggataaac taaagctata gcagttataa acccagttat agggtctgct
     9661 gcatatattg ctttttccat taagctagtt cttgtaactc ccattccatc atgatgacca
     9721 agtattgctc tatacatttc ttcgtcaccg aagttttctt ttttaagcag ttctactgtt
     9781 gttgtagcat gtccttcaca tatttctcct ggctttcttc caactatatc tgaatccaaa
     9841 tcatgtaaaa gacctgccac tgcccactct tcttcttttt ctggctctag tcttttggct
     9901 aattctctca taacagcttc aacagcataa caatgttttc tcattctatc agtttctaaa
     9961 tacttaaata aaatttctaa agcttcttct ctcattttca ccaatccccc tgttttttca
    10021 catatatgat atttttatat attaatacac ataaattcaa gtctttatat atattcatgt
    10081 atatttttca tgttatatct attctacacc tttatagtag tgtcctgcaa ctgttccaat
    10141 ttcatctaat ttcttataca aatctgtagc cttttttcca agtttataat tattactcaa
    10201 tacctcaatg tgagcttcaa taaccttttt aaccatctca ctatcttcaa ctgtaaaatc
    10261 tatcctaaat acatctattc caatttcctc taactcatat agattgtcca acatacaagt
    10321 aaccttcgaa ttgtaaattg tacttctaca gaatatatct tgtgttatcc tataacttgc
    10381 atccgtaaag tctcttaaag cataactact ttccttacat ttagcaactc tcttgtcctt
    10441 tttacaatct ctaacaacta ctcccatagg acagtattct gtaaccatca taggagcata
    10501 tccatatatt actgcttcaa tttctacatc tgtatatttt aaagtttgtt taatttcatt
    10561 taagtttagt tcttgtgaca aacaaactgt acttgctccc tcttctttga agtggtttat
    10621 actttcacta ttgaatgcat ttaagtagca atctatattt aagtcttttt tcttaaagta
    10681 ttccatagag ccccagttac caatttgaac cttattaatt ccttttatat tatccaatat
    10741 ctcaaattgc ttgtactctt tatttctaac aatccttggt gctgaataga ttaatttttt
    10801 gtcagtgact gctgtattat agtggttctt attcaaagta tctattttac ttgtatttga
    10861 caaagtatct atgttatttg tatttgaacc cattagttct ttaggaatac ctaaagacga
    10921 agaagtatct aaatccatag aaatacttga atctatagaa atacttgaat ctatagaaat
    10981 acttgaatct atagaaatac ttgaggccat ttgtaaagct tttgataatg tatttatatc
    11041 ttcataatag attaaatcta cattataatt taatactgct tctaattgct ccaagttctt
    11101 aactttaact ctaatcttag gaactgtatc aagttttttc tgtttattta ctctatttgg
    11161 ttggtatttt aatctattct tcttaaattt tctatctttt atctttattc tttcttcatc
    11221 taaaagctca atacaatccc ttctcatttg atttaacaca cttataggca tacttacacc
    11281 ttcatccagg tcaatttcta tctcttttaa cttatatggt gtatttccaa gcttttgaat
    11341 ttgtgtttct attttttctt tacttaaagc cacctttata gctttttcaa ctattttgtc
    11401 tccttctacc accgatttat ttccacaaaa atcacttata aaaagctctg gctttttacc
    11461 tagtttaata ctcacttttg cacgtatatt agtttttatg aactctttat cttgctgaaa
    11521 tgtagcttgt actctattca ttaattcgct gtcagaagtc ttatatataa gctgatttct
    11581 ctttgcttct ccaacaaaat ctaattctat caaatcccct ttatgtgcta ttgtagttat
    11641 ctctccatcc tttattattc ttccaatagt acctccacct aagttaattc catcaccttt
    11701 cttaagcgta ttttctagca ttactctaag tcttttgttc tttctattat aatctaaaac
    11761 ttttccaata tatagccctt gattattagg tctattagag ttcattatat ccttaccaac
    11821 ttcacctaat atatatcctt ttgtaaactt tctattaaat atggtataca aattatttat
    11881 tatttcctca gaaatactta tttttttctt atctacaaat tcattaatcg cttctctata
    11941 tcctgaaacc acagtagcta catactctgg ttttttcatt ctcccttcaa tttttaaaga
    12001 taatacacct gtttcaatta ttttatccaa atcttctata gtacttaaat ctctaggact
    12061 caacaaataa tctccattac tttttactac ttctcctgta tttatatcta tcaactcata
    12121 cttttgtcta catggctgtg cacacctacc tctatttcca gacctattgc ctatcatact
    12181 actcataagg cattgacccg agtaacatac acataaagct ccatgtacaa aaacttctat
    12241 atctacagtt gtattttcac aaatccattt tatctcatca acatttaatt ctcttgctaa
    12301 aacaactcta tcaaacccta cactctgaag gtattttaca tcttctaagg aatgtgctac
    12361 catttgagtg cttgcatgta gttcaaagtc aggtaatagt ttttttataa gtcttgccat
    12421 tcctatatcc tgtactatta aagcatcaat atctatatcg tataaaaatt ttacatactc
    12481 tacaaaatct tctatttcat actgttttat caatgtattt acagtaacaa agacttgcac
    12541 tccccttata tgagagtatt taacagcctc aatcagctca tttctatcaa agttatttgc
    12601 agatgctcta gcactaaagt ctttaccacc taaatacaca gcatttgctc cgttttgaac
    12661 tgctgctttt aatgaatcaa aagagcctac tggtgcaagt aattctattt ttttcatatt
    12721 tttctcctct atttatactt gttaggttaa tataattata tctataactt aaatatttgt
    12781 attaaattta tatatttctt actatatttt aaattcttca attaatttat atattagtta
    12841 tttatatttg gtccatttga gttaacatat acattattta ctatatttag tatatttcta
    12901 ttaacttata tattgattac tgtattttaa attcttcaat taatttatat actgcttact
    12961 aaatttaaaa cattttaatt aatttgtaca ctgtttacta tacttgaaat acttctatta
    13021 atctatatat tgcctactat acttaagaca ttttaattaa tttatacact gcttactata
    13081 cttaaaatac ttctattaac ttatatattg cttactatat tttaaattct ttaattaatc
    13141 tatacaatat ttgctatata taaagtatat caaataacag cttcattttt ttgtaaattt
    13201 acagaaagtt aattttcatt aaatgaatca tctttattga taaacataat tccaaagacc
    13261 actgccaaaa taaaaaaaca tattagtatt gatttttcca cgaaaatttt tgtaaaaaaa
    13321 gttcctaaaa tagctccaga tataaagaat ataataatag cataatactg taaactcttt
    13381 tttatcataa aaatattctt agtatgtata taatgaaata aagtttctgt agcacttctt
    13441 aaatttccag tacacattgt cgttgcaaaa ctattcccat ttacttttct aaaactctct
    13501 acttgcattg aacaaataaa agaaatagca acatttacaa acatattaaa tcttcctcta
    13561 ggaataaatg aaacaataag tattgtaatc atttcaatta taatgataac ctgacgccaa
    13621 tgaatctttg tcttattatt tgtaaaatac tttcttatct tctcggctat aaatacacct
    13681 aacataaatg ccaaaatagg aatcaaataa taaaatgatt cctttacatt accttctgct
    13741 atattaagcc caaataaaac tatatttcca gtttgtgcat tagcaaagac tttacctctt
    13801 accacataag tataaatatc caaaaatcct cctgttattg ccaacaaaga acataaaaag
    13861 aatgattcag acatctgact cttgcttgtc atatataaac ctctcgcttt ctaatgatag
    13921 atacaaaatc aaaatcattt tagattctat ttttcattga tataaaaaaa ttatttatat
    13981 ttaaatatta tctatattta tacatcattt atatttatac attatttgta tttatatatc
    14041 attcatattt atttatattt aaacattatc tatatctata tagcatttat atttatttac
    14101 atttaaacat tatctatatt tatatagcat ttatatttat ttacatttaa acattagcta
    14161 tatttatata gcatttatat ttatacatta aaagaagctg tctcaaaaaa caagagacag
    14221 caaatctttt agtttattcc acattttttg catcattatt taaccctgta cattttaact
    14281 gtaaatcata agctttgttt tgaaactcag aagctaagtt ttcagctata gtagctcttt
    14341 catttgcttc ttcaagttga gtacttaact cctcaatctt gtttttataa acatctaact
    14401 ctgctctaga accttctgtc gtattactaa gttcgaatat ttcttgcttt ttattttcta
    14461 taatctcaat taactctttc atcttagtct cagcttcacg attttctgct tctttttctg
    14521 ctatcgtaag ctttaaagac ttgatttcta attgaagctc ttcattagat gctccaacct
    14581 tcttactcaa ttcttcatta gctttaatca acttctcatt ctcatctgaa cattcaaata
    14641 aaaggtctga tatatttaat gcagttagta tcgcagcaac tgataagctc aatttcgggt
    14701 tttgacgtgt tattttatcc atttctttgt ctacaaaatc agcaatacta atcataaact
    14761 tctctgattt gtctccaacc attggatatt cagcgccatg gattttaacc attactttgt
    14821 tcatcctaac ctcccccgac attagttgtt aatttgatct taagttagca tttaattttt
    14881 cgcttaattc acttaatatc ttatcatgca ccttagctac atcttcatct gttagagttt
    14941 tatctttact tctataagtt attgaatacg caattgactt gtatccagct tctatttgag
    15001 aacctttgta aacatcaaat aacttgtagc tttctactaa tccttgacca ttttccttta
    15061 ttatatcttc tatttgtttt acaaatacat catctttaac aataagagct atatctcttg
    15121 atgtagatgg atattttggt aatggcacat aattctttgt tctatcagaa ttatcaaata
    15181 caaagtcaat atctatttca gcgacataaa ctctttgacc tagattgtag ttttctataa
    15241 catctggatg caattcacct aatgtaccta catatttatt attatacact attttagcac
    15301 atctaccagg gtggaaggta gtattattat cttgaggttc aatttcataa cctttaaatc
    15361 cgacatttac aagtatagtt tctatagttc cttttagtgc aaagaagtca acatctttac
    15421 catacatacc tacacacatt ctattttctt ctttaggtaa ttctgaatct tgtgggatga
    15481 atatatgtcc acactcaaat gcagatactt cttctatttt atgagataca ttagttgata
    15541 aaacatctaa catatttggt attaaagtag ttctcattac agaagtttct tctcctaatg
    15601 ggttaagtaa tttaacaaag tttctcttag cattaccttc tggtactctt atcttatcga
    15661 ctcccttagg gcttacaaat gaatatgtta atatttcatt taatcctaca gcagttgaat
    15721 tatcttttaa agcatccatg aatttttgtt ttgaagtttt aattcctgct gtcgtatttc
    15781 cttctaattg tacagaaggt atattctcaa atccataaat tctagctatt tcttcccata
    15841 catcagcttc ttgttccata tctgttctaa agcttggtac atctatttct aatttatcat
    15901 tagctaccaa attacattta aactctaatg attctaaaat tcctacaaac tgctccattg
    15961 gtacatctac acctaatagg tggttaattc tttgaggatt tactaccaat tttttaggtt
    16021 ctggtttatt tggatataca tctacaacac cttttaaaac ttttcctgct cctaacattt
    16081 caacaagttg tgcagctcta tttgctgcta tctctgcaag attagggtct aagtcttttt
    16141 catttcttga agatgcttct gacctaatac caactttttt agctgtcatt cttatgtttt
    16201 ctggtttgaa attggcactt tcaaaaagta cagtcttcgt attagaagtt atttctgagt
    16261 tagcaccacc cattacacca gctaaaccaa gtgatttttc tccatttgtt ataactagca
    16321 tatctttatc taatgttctc tcaacatcat ctaatgttac aagtttctct ccatctttag
    16381 catttcttac tactattctt ccagtctcta cttgatttat atcaaaagca tgaagtggtt
    16441 gaccaagctc taacattacg aagtttgtta tatcgactat gttacttata ggtcttactc
    16501 ctgcttctgt aagtcttctt tgcatccaat atggagaagg ttctattttt acatctgtaa
    16561 ccattctagc aacatatctt ctacataaat ctggattatc tatctcaact ttgaaatcta
    16621 tctcttcgtc actttctttt acttcgattt caggatattt tacttttgtt cctatagttg
    16681 cagctgcttc tctagctata cccatcatgc atttacaatc aggtctgttt gaagttaatt
    16741 caaaatctat taaagcatct tttaatccta aaacatcttt tatatctttt cctaattcat
    16801 aagaatcttc gtggtctaaa atatatatac cacctctttt atactcctca atgtaatgtt
    16861 catctatacc tagttcagct gctgaacaca tcataccatc tgataattca cctctgaaat
    16921 cagtctgttt gatttcaact cctccaggta acttagaacc atttacagct actggaatat
    16981 aatctccttc tgatatattt gtagctcctg taactatttg aacaacttta tctccaatat
    17041 ctactttagt tacaaccaac ttatcagcat ttggatgttg ttttatttct aaaatctttc
    17101 caaccaatat attttctatt tcttcaccat aataatctat tgtttcaact ttagttcctg
    17161 tcattgtcat tttatcagcg aactctttta catccatgtc tatatcaaca tagtctctaa
    17221 gccattttaa agatactaac atctacatac cctcctaatt aaaattgatt taagaatctc
    17281 atatcatttt cgaataataa tctaatatca tctatttcgt atttaagcat tgcaagtctt
    17341 tcaaccccaa ctccaaatgc aaatccactg taaacttctg ggtctattcc acaatttcta
    17401 agcacatttg gatgaaccat acctgaacct aatatttcta tccaaccttc atatttacac
    17461 attgggcaac ctttaccacc acatttgaaa caagtaacat caacctctgc acttggttct
    17521 gtaaatggga agttgtgagg tctaaactta gttttgatat cagaaccaaa caatttttca
    17581 acgaagatat ccatagttcc tttaaattct gccatagtaa catcttttcc aacaacaagc
    17641 ccttctatct gatggaacat tggtgagtgt gtagcatctg gcgagtctga cctaaaacat
    17701 ctacctggtg caattacttt tattggtaac tcttgacttc tcatagttct tacttgaact
    17761 ggagatgttt gagttctaag taatacccca tcattgatat agaatgtatc gctcatatct
    17821 cttgatggat ggtctttagg agcgtttaat gcgtcaaagt tgttttcaac agtctcaact
    17881 tctggccctt ctgctataga gaatcccatt ccgataaata tatctgttac ttcatctata
    17941 atttgagtta ttggatgctt cttcccaacc tttaaaactt ttcctggttg agtaacatct
    18001 atcacttcct cttttaattt tctttctttt tcaatagcat ttatttcttc ttttttagaa
    18061 tttatgctaa gttcaatgtt ttctcttacc tcattggcaa ccttaccaac tactggtctt
    18121 tcttcagcag ataatttacc catttcttta agtatggcag ttatctcacc tttttttcct
    18181 aagtacttaa ctcttaaact ttctacactt tctatgcttt gtgcttcttt tatttcagcc
    18241 aaagctgctt cacgtaaagc aagtaatttt tcttgcacac atatcaccct ttcgtttttt
    18301 tgtataaaaa aagcccctca atccctgtct agggacgaaa ggctatagtt tcgcggtacc
    18361 accctagtag tttaacaatt taaaaatcat caaaccacct ctaacaaact taacgcgttt
    18421 ttgacgtcaa agcctactgt aaaatttcag ctctgttact ccagagggaa cttctcatga
    18481 cctcttagaa aacactccca gcctaggtgt ttatctcttt actaagttta atcaaaatac
    18541 tttcctcttt cattgcattt acaatattat attgtttatt ttagtattat atcatttcca
    18601 ttcaaattat gtgactattt ttaatatata tccaatacat aattaattta attatttttt
    18661 atataatata tatctaatgc ataattaa
//
LOCUS       DAEQJM010000069        17471 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.070, whole genome shotgun sequence.
ACCESSION   DAEQJM010000069 DAEQJM010000000
VERSION     DAEQJM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17471
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.070"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(139..759)
                     /locus_tag="KRQ43_002980"
     CDS             complement(139..759)
                     /locus_tag="KRQ43_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH2743324.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(1073..3211)
                     /gene="vanT"
                     /locus_tag="KRQ43_002981"
     CDS             complement(1073..3211)
                     /gene="vanT"
                     /locus_tag="KRQ43_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH2743325.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(3229..4035)
                     /locus_tag="KRQ43_002982"
     CDS             complement(3229..4035)
                     /locus_tag="KRQ43_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH2743326.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(4032..5132)
                     /gene="vanG"
                     /locus_tag="KRQ43_002983"
     CDS             complement(4032..5132)
                     /gene="vanG"
                     /locus_tag="KRQ43_002983"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBH2743327.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(5393..6475)
                     /locus_tag="KRQ43_002984"
     CDS             complement(5393..6475)
                     /locus_tag="KRQ43_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH2743328.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            complement(6525..7226)
                     /gene="vanR"
                     /locus_tag="KRQ43_002985"
     CDS             complement(6525..7226)
                     /gene="vanR"
                     /locus_tag="KRQ43_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HBH2743329.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KDLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(7660..10191)
                     /locus_tag="KRQ43_002986"
     CDS             complement(7660..10191)
                     /locus_tag="KRQ43_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH2743330.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVKEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(10299..10916)
                     /locus_tag="KRQ43_002987"
     CDS             complement(10299..10916)
                     /locus_tag="KRQ43_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH2743331.1"
                     /translation="MCKKTYLLVVSILIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIITPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(11278..12162)
                     /locus_tag="KRQ43_002988"
     CDS             complement(11278..12162)
                     /locus_tag="KRQ43_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH2743332.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLVLSKRDIDLTLRRFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAVKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(12353..13603)
                     /locus_tag="KRQ43_002989"
     CDS             complement(12353..13603)
                     /locus_tag="KRQ43_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2743333.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFIYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDCKAI"
     gene            complement(13825..14589)
                     /locus_tag="KRQ43_002990"
     CDS             complement(13825..14589)
                     /locus_tag="KRQ43_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743334.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(14583..15308)
                     /locus_tag="KRQ43_002991"
     CDS             complement(14583..15308)
                     /locus_tag="KRQ43_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743335.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(15310..15678)
                     /locus_tag="KRQ43_002992"
     CDS             complement(15310..15678)
                     /locus_tag="KRQ43_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2743336.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(15854..17398)
                     /locus_tag="KRQ43_002993"
     CDS             complement(15854..17398)
                     /locus_tag="KRQ43_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH2743337.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQFISKYAIQIILIMAIICMMLIFYIIYDKLNFKIKLQKIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIDLNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
BASE COUNT         5998 a         3084 c         1745 g         6644 t
ORIGIN      
        1 tgaactaagt ataaataagt tttatatatt ttagtttaca aaagaactaa aaattttgta
       61 ccttaataca aaaaataaaa cgtatcttaa aataatttag tactaaatca ttttaagata
      121 cgttttattt cgtacaagct aaatcatttt atcatcttta tcattgtgat gttttttatg
      181 atggaaatca taattatgat tttcaagatt tttatttact ctatttccaa tcttccatga
      241 caaaaacacc aataatataa atgatgctat ctttaaagga cttgttataa aaccttctat
      301 atcacttgcc acgtaactta taactataaa cattacaaat tttcctgcca acattgctgg
      361 cacaaaatct tttaaatctt ttttaccaaa agctgatgcg atagtaacta aacaaccagg
      421 cataaatgga caggcatacg ctataaataa taacttaaat ccctgtttat ccatccaact
      481 tattgctttt tcagttttac tatttctcaa cttattaaaa agcttactat cattaaatct
      541 gcttattaat aagaataatg aagttgtccc aagtcctgag ccaatccatg ataacaaaca
      601 tccaataaat aatccttgta ttgcagcatt tgctgtaact atagcaacaa gtggtaaggc
      661 tggtataaag ctttctataa atgcacttaa taagccgatt attgtggcta acacccaata
      721 attttgagtc aaatcaagta attcttgtat atactgcata ttgcttttcc ccttttttaa
      781 ctttaactat tattatatac tctatatgtt tattatatac caatctcaaa aaatgaatct
      841 aatattaaaa agtaaataat ctatataagt ttacagttaa ggtataatta ttttattata
      901 tattataaca aaaaaggtga tgtttcaaaa taaaaatctg aaacatcacc tttttataac
      961 ttaaattgtc atgtaagtta taaaaaatat atattagaca taatattact aaaaatgtct
     1021 agtcagagta aaataaatta cacagtacaa caaatattac tatttaattg agttacttct
     1081 ttataacatt taaccttctt cctactctgc tcaataattc attcgatata ctacatgagt
     1141 tatttgcaac ttcagaagca gataattcag ataaattatc tcttcctatt attattgccg
     1201 tattaccaac ttctacatta ggtatatctg taatatcaac agcaagttgg tccatgcaaa
     1261 ttcgacccac tattgctgct ctacaaccat ttattattac gtaacttttt ccacaggata
     1321 aatttctagg tataccatcg gcatagccaa tagataatat agcaattacg ctatctctgc
     1381 ttgcaataaa gactcttcca tatccaaaac tatcatcttt ttgtattttt ctaataagaa
     1441 ttacttgtga ttttaaggat aaaacaggtc gtaaatcaag ttgcaattta gtcgtatcat
     1501 ttggagaact taatatcccg tataatgcaa ttccaattct tacataatta cacttaagat
     1561 tgggataatt aaaaaaacca taactacttt gaatatgtac tttaggaatt tttatacctt
     1621 tttttaacag aaaatcaatt aacttataaa aacattcaat ttgtttattt gtaaagtcta
     1681 catcttcatc tttcagacta tctgaaacac acaagtgtgt aaatatgcca catatatcta
     1741 agtattttaa tttaaatgcc tttaaaattg acctcacatc attaacatca aaacccagtc
     1801 tgtgcatacc tgtatcaatt ttaatgtgtg attttatgtt gtatttctgt ttgtttaaag
     1861 agatagcatg attaaggtca ataacactct gtgtaagatt gtatttatga agttcctttg
     1921 cccttattgg gttagtatat ccaagaatca atatttctcc tagtattcca tatcgacgta
     1981 aatcaatccc ctcatctatt gttgctactg caaatgcttt tacacctatt tggtttgcac
     2041 aagtcgctac ttcaaaagca ctatgaccat aggcattagc ttttacaact gccatcaatt
     2101 cacaatcttc tggcatagct ttttgtatca tctttacatt atgttccaaa ttatttaaat
     2161 caatttcaat ccaagctcta ttggtattta ccttatgttc tcctttcaag tcttttttta
     2221 gaggtttaag aatcaatata ataattatag aagctataaa agatgctata cttaccacta
     2281 tataatgaat aaggctattg tcaaccaaga cagtttgtat tccgaatatt ttagaaaaca
     2341 tacgaataac aacaatcatc ataggatgta taatataaat aattaatgat gatgttcgca
     2401 ataacctagc tcgagaacct tttaaaaatg ttaaggctgt aaataagaaa tacatacatg
     2461 gcaataacat aatatacatg ctatcatgac gctgtacccc tagtttatgt aaaaacattc
     2521 cctcacataa cataagtaag aatgatataa gaaatccaat caagctattt ttagttgaca
     2581 tataattaga tttattagat attattccac caagtatgaa aaatacaggt gcaaaaaata
     2641 taccatttcg tgtataatct gatacttcaa aaatataccc atataaattc tttaatagtg
     2701 gtattttttc taaaaaacca taataactat caccaaacat accaattaca taaataacaa
     2761 tagtgattac taatgagtac tttaaaccta gtttttttac aagaaagtat gcaatacttg
     2821 caccaataat tgatgcaggt agataccata aatgatataa agtcccatca aatacaatgt
     2881 ccttaataat attgggcact aaattattca tggaaaaata tccagtgtaa atatttaagg
     2941 gaatataaat tacaatagct atcccgtaaa taaataatac attttttaga aaagatttca
     3001 gtttattaca attataatta tatgttgaaa ttagaaaaaa gcctgatagc ataaaaaaga
     3061 atggcacagc aatacgagca attatactag ttaacacaaa gtcagccatt ttactatatg
     3121 ataataatgg agatgtatga attgcaatta taagtaatgc agctataatc ctaaaataat
     3181 caagccctgc ataagattta ttcctaatca ttcttgttcc tccatttctt agtcctttct
     3241 atttctccaa aatgtcacaa taaaaccatc cttattgtta cccgatattt gatatacaca
     3301 ttgttcaggt atagagattc tcacttcttc tttagtatga ataggcacat aaaagatttc
     3361 tataattttt tctttatctt ctatttttaa acaatttgta tacgaaaatc tcttaatata
     3421 ttctatatat tcttcaaggg cgagattcat tttattgata atctcagaat gtggatatcc
     3481 gacataacga aaatgccatg gttcttgaga tattcctgtt atttcttctt ttttacactg
     3541 ataacgctct ataaaaccat aatgtagtgc tgccttacgg aactcattac aaataccatt
     3601 ataaggaaat tcagggcaga taaaatctat aacctctttc ttcaacccta aatcaatagc
     3661 aagccctgtc tgatgttcac tgtgatttgg aagtgctaca aactttttag taaagtcttt
     3721 tccattgtca cgcagagagc ttgaatatat atcttgttgt tcctctgcag tacgatatcc
     3781 acttacaggt actatttcat ttattccaca tatacttttt aaaatatttt gtaaaatatt
     3841 tgtagcttca cgtttcataa gaatacttgg aaaccttgta tctacaggaa ttaaatctat
     3901 atcttcagat gttttaactg gtaaaaaagc atttactaga attagattcc catcataaac
     3961 tttatcttta gtcaataaga tagtatttgt cattttatct tctttatttt tatctaataa
     4021 aatattattc atcattttat gtacacctca attatcttat ccaatatttc ttcaaaagac
     4081 agtccaatac ctttcatcat attcggataa cgactatgag aagtaaagcc aggaattgta
     4141 ttgacttcat taaaaataat ttcaccagat ggagttaaaa acatatctac tctagcaaat
     4201 ccagaacatc caagagttct ataaataatt tttgctgtct cttgtattct tttctcacaa
     4261 tccaaatcaa ttctagctgg catatgaatt tttgaacttt tcaatgtata tttttctgta
     4321 taatcaaaaa atccttttga caattctatt tcatctactc ttccaacaag taagtcatcg
     4381 tttcctaaaa ctgcacaccc tacctcaaaa ccatcaatat tttcctcaat tattacttca
     4441 ttatcatgtt caaaagccaa gtctactgct acttgtaact cttctttttt ataaatttta
     4501 ctaataccaa atgatgaacc tgcacgcaca ggttttataa ataatggata agttaagtct
     4561 tttgacagtt cagccacatt aaatttatct gagtatttta gtaatattga ttttggtact
     4621 ttaatacctt ctgaatgaac aagtttatgt gatttgtctt tgtccataca taatgctgaa
     4681 gaaagagtac cacatccaat aacctgtata cctgccaatt caaataaccc ctgcactgtt
     4741 ccatcttctc cattttttcc atgcaataca ggaaatacaa aatcaagttt agtgtattta
     4801 atatcatttt cacatgattc aatagcacta tttggaatat gattctgaga aacagcatca
     4861 ggaattaaaa attcaataat accatttttg acacggttct gcgaaacaat aactggaatt
     4921 atatcagtat ccctttcaaa ccaagtgtta ttctggatat tattataatc tccaatataa
     4981 tgataccaat taccctccct tgtaattcca attggtataa tatcatattt ttccgtattc
     5041 aaattctcaa gtactgcaaa agctgattgt aatgatacat catattctgt tgagtttcca
     5101 ccaaatataa ctgcaatttt tttattattc atctttgatt ctcctttgtt gatttattta
     5161 tttttataca atctacagaa acatgttaaa atactttttc tatttcaaat ccaatcaacc
     5221 ttcacttaca attgcatctg ttccacataa tatattttca catttttcta ttgatataat
     5281 tactgtatca aaataaaagc actcttgttt tgatacagta attatatcaa taacaagagt
     5341 gctctttatt tatttatcct aaagaatttc ctattttttt atacttaaat tcttacaaat
     5401 ttcctacaat cggaataata accttaaagg taattatatt gttctcgcta tgagctgtta
     5461 ttgtcccgtt atgaagctcc actatttctt tagctatagc aagtcccaac ccagctctac
     5521 cactgtttga attacgagat gtatccaacc tgtaaaattg ttcaaaaata cgctcaagtt
     5581 tttcctctgg aatcgtattg ctatgattta taaatttaag ctttatataa tcatcctcct
     5641 gtacagctgt tatttcaata gtagtatctt caaaactata ataaacagca tttcgtaata
     5701 agttatcaaa tacacgttgc attttattaa catcacacct tatcatcata tttggtgtaa
     5761 cattcagtgt atattttaaa ttcttactca tcaaagtagg tttaaactca tatgttagtt
     5821 gttcaagcat acgagttaag cttactgtac tgtattcaag tgatatattt gataaattaa
     5881 accttgtaat ttcaaagaat tcattaatta aatcttcaag acgctctgcc ttatccaacg
     5941 aaatagataa atattttttt cgcagttctt cagaaatctg actttcatct cgaagtagtg
     6001 tcagataccc tataactgat gtaagtggtg tttttaaatc atgtgcaaga taaacaataa
     6061 gttcattctt acgttgttct gccatttgtg tctcaaattt acgttgttca agtatatgtt
     6121 taattgagtt tattttcttt tctattgcca ataactctgg agataaagcc acttctccaa
     6181 catcttcttt gataagagag tcaatacctt gatttatttc actaaaatat tttgtaaacc
     6241 aatttaaata aacacggaat attataaaaa acacaatcac catagctagt atcatgaaga
     6301 gctccatgct attacggaaa atctgctgat ataaattcaa tgcagcttta tattccatac
     6361 gaaaagcatt ttcaaagaat gatactatcc agatagaaaa cttaccatac aatataaaag
     6421 aatataaaat ccatatgaaa ataatggcta taaatgccat taaagctgtt ctcataaaaa
     6481 ttttatttct cacttgagta aagtcaggat tgactttaat atttttactt ttcaattgta
     6541 taacctactc cccatacagt ttttataaat ttcgggtttt tagaaggttc atgaattttt
     6601 tcacgtaatc gccctatatg agccataact gtgttattat tatcaagata tttttctccc
     6661 catacagctt caaacaattc ttcagaagga accacttttc cttgatgttc acataaatac
     6721 caaagaatag aaaattcaat cggtgttaat gctacttctt tcccaaataa actacattta
     6781 tgtgtttctt tattgataat caatccttta atatcatact cattaacaat tatcgactgt
     6841 tgttcataag aattattata tcgcatatat cttcttaatt gtgtctttac tcttgcaaca
     6901 acttccaaag ggttaaatgg ctttgttata taatcatcag cacctatggt taaacccatt
     6961 atcttgtcta tatcttcaat tttagctgtt aacataatga taggataata gtatttttct
     7021 cgaattttct ggcaaatatg aaatccatca atatcaggaa gcataatatc taaaatagcc
     7081 atatccaaat ctttagattc aatacattct agagcttcct tacctgtata aaacttgtat
     7141 actgtaaaac cttcattttt taaatatact tcaattaaat ctgctatttc tttttcatca
     7201 tccacaatca aaatattttc gttcatagat tatttttcac tctccttatt atcgaggtca
     7261 tcatttataa tattggtaaa tttacatatc aaataattac aagcatattt gtaactaatt
     7321 tttataagaa aagaactact acatcagaat gtgttgatgc tactattgga acacaaaaac
     7381 tgagattaat tgttattata aaaactcccc taacacgtcc ttattatcgc ataacaggta
     7441 ttaactttca ataaaaatat ctatcagtca aacacaattc aatttattat accagagaca
     7501 atccatataa aaaacaatta aacctatgta tgtaaccaca gacattacta aaatttccat
     7561 gttattttat ataaaaattc aaaaaaggag ttgaatttaa aatttgatta gaaaaaaatc
     7621 aattttgaga caactccttt ttattttaat gtatttaaat tatagtatat cagccttcat
     7681 aatatcctca aaatcacctt tttcagatat taatcttatc aatttaacag tacagcttaa
     7741 atcatttata agtatagctc caactaatga accatctttc ataaataatt ttttatatat
     7801 tctttgacct tcatcttttg atgaaatttc tttatcaaaa ttttgtatat taccaatact
     7861 aaatactttt acattcattg catctaatga aactggatat acttcacttt caaatgtcaa
     7921 attatctcca cttgcatttg ctcctgctat ttttcccatt tctactgaag atggccatat
     7981 tgctaaacta atatttccca cttgtgcaac atctccacaa gcatatatat ctttaacatt
     8041 tgtctgtaat gtcttatcta caacaatacc tctatcaatt tttacagatg tatcctgaac
     8101 catttgagtg tttgctctta caccaattga aaatactacc atatcacagt caacactatc
     8161 tccatcttta aatacaactt tttgagcttt tccatcacct tcaataccat caactgctac
     8221 acccaatctt acatctattc ctgtatctct tacacattgt tctaatattt tactaccctc
     8281 tttatcaagt tgttttgata gtatgctatc catggcttca actactacta cttctaatcc
     8341 ttttagtcta aattcccatg cagcttcaag tcccaataaa ccgccaccaa tcactacaac
     8401 tttcttagat ttttctagtg cttcttttac actatataaa tcttttatat ttctaagagt
     8461 aaacacattt tctaaatcat ggcccttaat cggtggtata aagtttctac ttcctgtagc
     8521 tattacaagc ttatcaaatt taatagctcc atcattcact ataatagttt tattcacttc
     8581 atctaattta tctacattcg ttcctaatat tactactata ttatttttat cataccaatc
     8641 tttatcttcc atgtagaaat ctgaaccaag ttcttcattt ataccatcag aaagtgcagg
     8701 tctatagtaa gtcaactcat cttcattaga aatcatagtt atcttacaag ttttatttct
     8761 ttttcttata gcatctgctg cataaaaacc agctgctcca tttcctacta ttacgaaata
     8821 ttcatcagta tcttttctaa aagtaacttc atcttcttca acttctataa attggtcttc
     8881 cttagctcca catacagggc atacactagg agcactatca ccttcaaaaa cttcattaca
     8941 aattacacat ttaaatttct tagttttctt tttacttcca aaagtagaat ttaacttatc
     9001 taggaattta cctgtataag aatgtaattt atcaatctct tcatttgatg gtttaaagtt
     9061 aacagcaaaa ggttttactg ctgtcattct aagctgactt attctctcca tagcattttc
     9121 tataccttct ccactccatc catatgaacc aaatactgaa gcaacttttc caccatgaag
     9181 aactgggttt aacgatatta atatatccca tataggcttt aacgcatctc ctaatattgt
     9241 tggtgttcca aataatacac cttgtgatac tgctattttt gccaaaatat cttcttgctt
     9301 atgctctatt acatcaaata aatttacttt atagttgcta tttttttcaa tatatgcttt
     9361 tatagcttct gccataatct ttgtatatcc atgtgcagaa acataacaaa ttgtaacttc
     9421 tttttctaac tttatttgtt cctttacact ccagttataa taaaggtcta taatttttct
     9481 aggattttca gttaatactg gaccatgacc tggacataca gtatctatat ctaaatcttt
     9541 tatcttttct atagcagtta ccatagatgg tttaaatgga cccattatac aatcataata
     9601 gtatcttaaa gcatccaagt aatccttttc ttcattttca tcaagtgtat ttactatctt
     9661 atcattacta tagtgactac caaatgaatc acatgttaca agagttttat cctcttttat
     9721 atatgtgtat atagtatctg gccaatgaag cataggtaca gagaaaaatt ctaaagtttt
     9781 gtccccaatt gataatgtat ctccatctgt aactgcaaca tattcaaagt ctttgtttac
     9841 gatttcctta agatatttaa ttgctgtttc tgaagctact acttttgcat ttttagctaa
     9901 atccaaaagc ttttcaacgc ttcctgcatg gtctggttca gtatgactta caacaatata
     9961 gtctattttt tcaaaatcta tatttaaatc atttaatctt tcaatataat tgtcaaaatg
    10021 cttatcttta actgtctcaa acaaaactgt tttttctgtt ccttttaata catatgaatt
    10081 ataagtagtt ccataaggtg tatacataat tatgtcaaat actcttaaat cagggtcaag
    10141 tgaacctacc caatataaat tttcttttat ttttagtgat ttcaatgaca taccgtactc
    10201 ctcctaaaat agttatttag tctctttata ccctgcttgt tatattttaa acaaaattta
    10261 ttcaaaaaag aaattatttt aaagatagtt taaatcttct aatcttcttt ttctaccttc
    10321 aatacagttc cctttttaga atctactttt atgtcatatt catttttatc tttatctatt
    10381 cttattttat aaaaagtaac atctaaatct ttgtctaaac tccattcttt aaccattcca
    10441 ttttgttctt ttaatgcaat ttccatagct tgttgaggtg taattatgtc atttaaatct
    10501 aatttttctt ttctagcaac tccatttaaa tcttctgaat ctaacttttc tgttttatct
    10561 tctaatacat cttttgtatt agcatcaatt ttcatcttat attcattatt atcatctaca
    10621 ccttccacag tataaacaaa tttatttaaa tctctctcaa gacttaaatc tactatatca
    10681 gcatccttgt atttatcttt aaatatgttt attgcatctg tgtatggcac tttaaaatct
    10741 tgttccatta aattttcatt atttttttca tcttttaaag cattatttga agcatttgcc
    10801 tccttttttg tattatcttg tgcttgtcct gaatccttag ttgggctccc actacatgca
    10861 gttaataaac ctgctataag tatacttacc actaataaat acgttttttt acacataaaa
    10921 atcctcctta aatatattaa tttattctat attatgccct ctaaaccctt tatttaccct
    10981 tttatattaa aaattcctcc tattttatca attttaaaac tttatattta ctaaaattaa
    11041 agttacataa aaattatact gtctcaaaat agaaacaagc atctttttca ttgttgaaat
    11101 aataaaaata tattttattt cgtacaaaaa gagtgcctca tgaactaaaa agttcatttt
    11161 gagacactcc cattctttta tatttttact tacaaaataa cagtacttat taatttttta
    11221 caaaccttat aagtatatct atattatatt cttaaattta aacactatat taaaaaatta
    11281 aattttgttt aattctttta ctgttaaatc cattttagga tatggaatcg taattccttc
    11341 ttcgtcaaac ctaactttaa cctcttctag taaatcaaga taaattgtcc aataatcttc
    11401 tgtcttgcac caaactctag ttgcaaattt aacagcatta tctccatgtt ctactactcc
    11461 tataaatggt tctggctcat ttattattaa tttatgatta ttaacaatat ctttaagtac
    11521 tcttctaaca tgtagtatat catcttcata ccctacacta aaagtcaaat caactcgtct
    11581 agtattcttt gctgaatagt ttattagact atcatttgat acagaaccat taggtataag
    11641 tatctgttta ttatctggag taaccaattg tgtataaaaa agtcctattt gttcaaccgt
    11701 tcctccatgg cctgctgctt ctacgtaatc tcctacttta aaaggtctaa tcaatagtat
    11761 aataaatcct ccagcaaaat ttgatagact accttgtaaa gccaaaccta ttgctacccc
    11821 tgctgatgct atcacagcag caaaactgga caaactcatt ccccaatatt ccagaacaat
    11881 gattataacg gcaactttaa gtacactcaa aagaagagac ttcaaaaacc ttcttaaagt
    11941 taaatcaata tctcttttac taagtactaa cataacatgg tttacaaatt tttttattat
    12001 tttaaatcca atagaaagta taagtatacc tattataagt tttactccgc ttgtagtagc
    12061 ccattctagc agactttcca ttatacctcc catatccatc ttattaatgt ctaaattatt
    12121 taaatctaac ttgcttatat catctatttt cgtcgtatcc ataaaaaact ccttacctta
    12181 tattttagaa ccaatattat agtttaaagt tcttattttc tatttaatat aatacaatac
    12241 catttgtaca tagtaaacaa gatttatatt ccaattatac atcttaggaa aatgcaaact
    12301 atttgttata tatatgcaaa atataatact aaattaaact attaataaaa cactatatag
    12361 ccttacaatc atcatttttt acccctatat gagatgatac tatagttata atacttagta
    12421 ctataaatac tacaaaacct tttttatatc catcaactat attatatgaa tttacttgta
    12481 aagagatagc tataatcaaa ttaataattc cacttcctat aaattcaaaa gtattaataa
    12541 cactagttgc cagtccagaa taaatttctt tatttttata cttggcatca ttaaaaacct
    12601 gtagatgtga cataactata catcccataa taaagaatga tattggtaaa actataattg
    12661 gtggttttac ctggtataca actacaatta caatccatat aaacaaatct atcattgctc
    12721 caaattttat tatattaaat ttgctagacc ttattttagc aaatacaaaa tccataatta
    12781 ttgaaccaaa tataaatcca tatgtaaaaa atgatactat aaacgcagaa aaactcttac
    12841 tcacaccata aacgtccatt atgtatctta ctccccacaa gcttataaat gcacttgtaa
    12901 gaccaacaaa agagaacatt atcattgaat tataccatgt tgatttgttc tttataacag
    12961 acttaatacc atcaacaata ttaaccttct ctgacttttc atagggttca gtatctacat
    13021 tgaatccata ctcttttggt gtatctctaa caataatata tataaaacat ccaattacaa
    13081 caccaattat accgattaat aaaaatgaat ttctccaacc aacaagttca gacaaaaaca
    13141 caagtggaaa agtagcaaga actccaccta aatttcctac aaatgaaaat ttagctgttg
    13201 cagaagcaaa ttctgactta ttaaaccatc tcccttgaat ttttaaaata caaagtaata
    13261 ttactgatgt tcctgcccct acaattacac gagaaatata tgctaattct atactttgaa
    13321 tcaaaccaaa taaaattgac cctaaacttg ccattattat tccaagactg ctaatttttc
    13381 ttgctccata tttatcaatc aaaattcctg caggtatttg cataaatgca tatgcatata
    13441 ggcaaaagga tgctatattt gaaatttgta tagaattaaa acctaactca tttgctaaat
    13501 tgtctgaaac aacagcagtt gacatcctta aaaataatac taaaacaaat gaaaatgtaa
    13561 ttatacccca aacactccac ttagcctttg tataactttt catatcttct ccctcaaatc
    13621 catatatttt taaattttct tgatataact tatataaagt gtatagttat tcttacaaat
    13681 ttttacacgc aatatcatta tacaacatat gtatatattt aactagaaat aaaatactat
    13741 tcatattata tacatgaatt aactacataa ataataagag ccatctttta acattactca
    13801 aaagatggct ccatataaaa acatttattc taaatttaat tttttatcta atataaattt
    13861 tgtagcgaaa aataacgcta ttgcaactac aagactacca agtattgcaa gcataaaact
    13921 aggactctga taaagatgat ataccatatt tgtatcttca tttggtaaga tgcttccaac
    13981 tgcatctcca acaattgata ttactatatt tatagctata aaagaagcaa atgccactat
    14041 gtttctatgt ttattgaatt ttggtaattg tcccattgag attgatgtat ataataacaa
    14101 aataaatgat gaatatgaaa taaacattac tactactaat aataaaatat ctaaaaagtt
    14161 ttcagaaatc catttaaaac tagtgttaaa caaatctaaa atttcaggta gtaaaattcc
    14221 agaagtacca aaaagcataa gaactccaaa agtgaatact gcaactataa aactaagtac
    14281 agcgtatata agtgctgtta tacatttaga taatataagt gaactagtgc taacaggaag
    14341 agtaaacatt aaataacctt catcccccaa aagatttttt ctaaaccttt gaattgtaac
    14401 tacaatagtt aaaactccta atgccataaa aagacttgtt aatactagta ttcctattcc
    14461 ctgtacctga agtatatttg tattcataaa tattccatta aatacagcta ctatcaatat
    14521 ggctatatat aacggtataa atattcttcc acttgctttt aactcatatt ttaataattt
    14581 acctaacatt taaattcctc cctaaataat gcatctatag attttccttt ttcttctctt
    14641 attgcttcaa cgtctccttg taacactatt tctccttttg atatgaatat tatctcatca
    14701 catatgtttt ctatttcact tattaagtgg gtagcaatca gtaaagtact atcttcagaa
    14761 taatttttta atatagtctt aagtatatat gaccttgcag ctgggtcaac accacctata
    14821 ggttcatcca atatatatat gctcgcattt cttgacatta ctaaaataag ttgaactttt
    14881 tctttagttc ctttagacat tgtctttagc ttttcattta catcaatatc taagctttta
    14941 atcatctcat ttgctcttct aacatcaaaa tcactataaa aatcatagaa aaacttaagt
    15001 aaatctgata ccttcatcca atcatttaaa taagttcttt ctggtaaata tgaaactatt
    15061 tttttagtat ctatggatgg tttcattcca tttatcataa tttcaccatt atcaggctgt
    15121 aataatccat tcattagctt aatcattgta cttttaccac ttccattagg ccctaacagc
    15181 ccgactattt ttccctttgg tatatttaaa tcaatatttt ttaaaacatt cttagttcca
    15241 taactcttgt ttacaccttt aaattcaact attccatctt gagaaacatt gcttatattt
    15301 ttatccattt tataattctc ctttcagatt ttctgtaata agttttagca tttcatctct
    15361 atcatatcca agcttttcta aggttacttt taatgtattt atctccacat tagctatttc
    15421 ctctttcata gcttttattt tttccttatc atctgttaca aatcttcctt tagttctctg
    15481 actataaact aaaccttgtc tttcaagttc tgttagagcc ttttgcattg tatttggatt
    15541 aacttccgca tcttctgcta gtgctctcac tgtttctaat ttagatccta ttttaatttc
    15601 ccctgaaatt atttttaact ttaaatgttc tactaattgt atatatatag gtttgttatt
    15661 atcaagttcc cattccatgt tcatgcctcc ttattatatt attgtattaa tttattaata
    15721 caataatata ataatacaaa gtatatgtca attacttttt agtaaaagta taaaaaattt
    15781 cacaaaaaaa atgaacacta cattagagtc catttttaac acaatttatt aaattcttta
    15841 tattacagat taattaccct cttaccaagt tggatacaat taaatgttca aattcttcaa
    15901 ttggcattgg ctttccaaac aaatatcctt gtgccatatc acactttact tcttttaaaa
    15961 gtttaaactg ttcttctgtc tcaactcctt ctgatatgac tttcataccc aactcttttg
    16021 ccatttctat tactttagta acaattattt tgcttctttt actattataa gtttccataa
    16081 taaatttttg gtcaagtttt aagatatcca taggaatttc ttttaacata tttaatgatg
    16141 agtaccctga accaaaatca tccatagata ttaaaaatcc tatttttttt aaattattca
    16201 ttatatcaat taaaatatca aaattatcaa atatgatact ctccgttaat tcaagttcta
    16261 tatactttgc aggtatattg tatttatcaa ttatattttt gtatgtttct ataaaattat
    16321 tgcaatataa atgtattctt gaaacattaa ctgaaacagt aactggattt attcctgcat
    16381 caatccattt tctaaggtat atacatactt cttcaagcac atataaatct aaatttataa
    16441 caaaaccgtt tctttcaaaa aatgggataa attcatttgg aggtattagc cctttatcag
    16501 gacgtttcca cctaacaagt gcttctgaac cttgtatctc tcctgtatta agatctatct
    16561 taggttgtaa gtatataata aactctttat tttctaaact tgaaaacatt gtattttcca
    16621 tctctttttc ttttatctct tggtcatgaa tcttattatc ataaaatgca tatgaacttt
    16681 tatgtcctcc ctttgccatt ttatgaggta tattagccct atctatgatt gagttgatat
    16741 ctctatcttc tggaagtata aaatagattc cacaacttaa aactaactta tacttttctt
    16801 cttgattatt attaaacaag tctaattcct caaatatagt ttttaacctc tttgttatat
    16861 cttcttcttc tatatatttc ataattataa taaaattatc cgcagatatt cttgcaaaca
    16921 tttcctcttc aaatatatta ctcttaataa tttttgttaa attacgcaaa atttcattcc
    16981 caacttcata tccaaataaa tcatttatat atttaaattt atcaatatct atatataata
    17041 aagcatactt tacttgagta tttttacata gtattttgtt agcatcaatt acaaatttat
    17101 ctatagtatt tgctcctgta agattatctg tatatgctat cttttgcaat ttaattttaa
    17161 aatttaattt gtcatatatt atatagaata taagcatcat acatattata gccataataa
    17221 gtattatttg tattgcatat ttgctaataa actgattatt agacacaata gactcaaagt
    17281 tatttatgga gttgttttta tagagtttgc ataaagaata gactggtgtt gtgtatgtaa
    17341 tttgtaaaat tatacaaata aataaaaaaa acatcaattt tttttgtaaa ttcctcataa
    17401 aaatttcctc ccattaaaac acctctattt tattagcaaa taagtacatc tcaaaagttt
    17461 ccatttcttg t
//
LOCUS       DAEQJM010000070        17346 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.071, whole genome shotgun sequence.
ACCESSION   DAEQJM010000070 DAEQJM010000000
VERSION     DAEQJM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17346
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.071"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            62..1612
                     /locus_tag="KRQ43_002994"
     CDS             62..1612
                     /locus_tag="KRQ43_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBH2743338.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            1730..2620
                     /locus_tag="KRQ43_002995"
     CDS             1730..2620
                     /locus_tag="KRQ43_002995"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBH2743339.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            2604..3284
                     /locus_tag="KRQ43_002996"
     CDS             2604..3284
                     /locus_tag="KRQ43_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2743340.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            3429..4088
                     /gene="spoIIR"
                     /locus_tag="KRQ43_002997"
     CDS             3429..4088
                     /gene="spoIIR"
                     /locus_tag="KRQ43_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBH2743341.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            4139..4624
                     /locus_tag="KRQ43_002998"
     CDS             4139..4624
                     /locus_tag="KRQ43_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBH2743342.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            4826..5632
                     /locus_tag="KRQ43_002999"
     CDS             4826..5632
                     /locus_tag="KRQ43_002999"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBH2743343.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            5649..6077
                     /locus_tag="KRQ43_003000"
     CDS             5649..6077
                     /locus_tag="KRQ43_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBH2743344.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEENIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            6260..7648
                     /gene="tilS"
                     /locus_tag="KRQ43_003001"
     CDS             6260..7648
                     /gene="tilS"
                     /locus_tag="KRQ43_003001"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBH2743345.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            7682..9652
                     /gene="ftsH"
                     /locus_tag="KRQ43_003002"
     CDS             7682..9652
                     /gene="ftsH"
                     /locus_tag="KRQ43_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH2743346.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            9966..10943
                     /locus_tag="KRQ43_003003"
     CDS             9966..10943
                     /locus_tag="KRQ43_003003"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBH2743347.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKTHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            10936..11904
                     /locus_tag="KRQ43_003004"
     CDS             10936..11904
                     /locus_tag="KRQ43_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HBH2743348.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            12088..12678
                     /locus_tag="KRQ43_003005"
     CDS             12088..12678
                     /locus_tag="KRQ43_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH2743349.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            12697..13467
                     /locus_tag="KRQ43_003006"
     CDS             12697..13467
                     /locus_tag="KRQ43_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HBH2743350.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            13604..14572
                     /gene="dusB"
                     /locus_tag="KRQ43_003007"
     CDS             13604..14572
                     /gene="dusB"
                     /locus_tag="KRQ43_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBH2743351.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            14681..15160
                     /gene="greA"
                     /locus_tag="KRQ43_003008"
     CDS             14681..15160
                     /gene="greA"
                     /locus_tag="KRQ43_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBH2743352.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            15175..16704
                     /gene="lysS"
                     /locus_tag="KRQ43_003009"
     CDS             15175..16704
                     /gene="lysS"
                     /locus_tag="KRQ43_003009"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBH2743353.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            17013..17207
                     /locus_tag="KRQ43_003010"
     CDS             17013..17207
                     /locus_tag="KRQ43_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743354.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NIWADRVRANSYSYENKIAK"
BASE COUNT         7080 a         1721 c         3381 g         5164 t
ORIGIN      
        1 ttttttgctc cttaaatata aatatagtgt gatattttta taatacttaa ggaggtagac
       61 tatggaatta attaaagatg taattaaagt tgacaataga atagactttg gaaaatttca
      121 aacattcatt gaagcggagg cagttgtacc agacaaaaaa ttagatgtat atgaaattgt
      181 aaaaacagaa ggatacatat cacttaaaaa aattgaaatg gcagatggga agatactttg
      241 cagaggtagt tttaattata atgtaatcta tattgcagat gataaaaata ctatttctaa
      301 tgtagacgga aaagtagata taaacgaagt aatagaaaaa gacaatgttg ttcaagatat
      361 ggaatacatg ttattttcag aagtagagca tatggattgt actataatga atgagagaaa
      421 gattaaagta ggagctctta tgaatataag gggaagtttg tttgaaaagc aaaggttaga
      481 cattgtaaaa gatgtggcgc aagtggaagg catacaaaag cacagaaagg aaatttgttt
      541 tcaagatata gttggaatag aaaaagcaga aagttctata agagatacta taacaataaa
      601 cacagaggaa attcaatcta taataagttt aaatccatgt gttaaagtaa aagaaagtag
      661 agtgactgac aataaagtta ttattggtgg agtattagaa ataaatccgt tagcttgtac
      721 atatgagggt gaacttgtag agttggatag agtaggtatt gagtttactc aatttgtaga
      781 agtccctgga gttagtgatg gtatgactga agaagtattg ttgtctatgt cagattttaa
      841 tcatattttc aagcaaaata gtgaaagcaa cacaggtctt ttagaaatag attgtatggc
      901 ttgttgtaag gtaaaagtta cagatgaagt tacaagagaa gtattacaag atgcatattc
      961 gcctcaaaag ataataaaat ttgaccacaa acctattcaa ttaaataaga ctttaagacg
     1021 tagtgaagaa acatttatgg ttagagaagg cataagaaat gataatgatg atatacaaat
     1081 aaaagatatt gtaagcgttt gtccaaccat gtctatagaa aatagttata ttgaaggaaa
     1141 taaaagcatt atacaaggaa tcataaaagt tgaaatttta tttgtcccag ttgaaggttt
     1201 aaaattggtt tataaaatta gtgaggaaat tccatttgaa catgatatag aaatggataa
     1261 tctaactgat acagcatctg tgtttaatac agcatgtatt gataaagtcg aagttgattt
     1321 gaatagggac cagatagact tgattatcaa aattaagaga tttactgaag cattagataa
     1381 gaaagcagaa aattttatta tcaaaggaga agaccaaggt gtatatgatt tatctaaagc
     1441 tcctagcata atcgtatata tatgcaaaga aggagatact ttctggaata tagcaaaaaa
     1501 atacaataca acagaaaatg aaattgcaga acttaatgat ataaaacttg atgaaccaat
     1561 taagcctggt aagtgtctta ttttagaaaa aaaagtcgta ttagtagatt aatattaaaa
     1621 aatttaaagt aattaagtat aatagggtat tataataccc tattatttta ttttttgtag
     1681 tataatatta ttgttagtga tgcattattc tttaaacaag gaggatagaa tggattttat
     1741 aagactaaag agtagagcaa aaataaattt atccattgat gtcttgggaa aaaggcaaga
     1801 cggttatcat tttgttgaaa tgataatgca aacgatagat ttatacgata tagtaaagat
     1861 aaaagaatta gacgaagatg aaataaaggt aaaaagcact agtttagata ttcctttaga
     1921 tgaagataat attgtttata aagctgccaa aatacttaaa aataaatttt atataaaaaa
     1981 aggtgtagaa atattcatag aaaaaaatat tcctgtagca gcagggatgg ctggaggaag
     2041 ttctaatgca gccgcagtat tagtaggttt aaatcaccta tgggaactta gattatctga
     2101 agatgaatta aaagaaatag gacttaattt gggcgcagat gttccttttt gtatatcagg
     2161 aagacctgcc ttagctcaag gtattggaga aaagctaaca aacatcaaag gtttaccatg
     2221 tgatacaaat atattgatat gcaaaccaga cttattcgtt tctactaaag aagtttatca
     2281 aggattagat ttgaataata ttaaaaaaag accaaataat aaatatttga tagagtgttt
     2341 aaaatctgaa gatataaaag ctgtatcaga aagcatggta aatattcttg aaaatgttac
     2401 tataggtaaa cacaaagaaa taagtgatat aaaacaagta atgatgaaaa ataatgcttt
     2461 aggttctatg atgagtggaa gtggtcctac agtttttgga ctatttaaaa ataaagaaga
     2521 tgctctaatt ggaaaaaaag aattattaaa aaaatataaa caggtgtatg ttgttaatag
     2581 cagtcaaaaa ggggttgaaa tttgtggaga atttaactaa actgaacttg gataattaca
     2641 agccattaag agatgtagtc tttgagaatt taagagaagc aatcttagaa ggaaaattaa
     2701 agcctggtca aaggctaatg gaagtgcaac tagcagaaca attaggagta agtaggactc
     2761 cagtgagaga ggcaataaga aagcttgaat tagaaggttt agtcgttatg ttgcctagaa
     2821 aaggtgcgta tgtggcaaat atgtcattaa aggatattat ggatgtatta gaagtaagag
     2881 caagcctaga aggcttagca gcatatcttg ccgctgaaag aattagtgat gaagatatta
     2941 aaaagcttaa agatatatca gaagaattta aaaaaagcac tttggaatcc gatgtagatg
     3001 cgttattaaa acttgatgta gaatttcatg aatgtatatt taaagcaact aataataaaa
     3061 aattaatcca actaataaac tcattatggg aacaagtata tagatttaga gttacctata
     3121 tgtctgctta tgatacatca cataatattg ttgaagagca taaatactta cttgatgcta
     3181 taattaaagg tgatagtgag ctatccaaga agtatgctac agagcatata gaaaaagcag
     3241 agcagtttat gatagataag gctatgatta gtaaagactt ataaaatata aggtttaaaa
     3301 agctatttta aaatgattgt aatcatttta agatagcttt ttttattagt attaaaaaat
     3361 attatgaata aattaaattt aattggacat aattgatgat ataaatttat cttgaggggg
     3421 aattttcaat gagaaaaatt aagattagat tgggactatt aatattaagt cttatatcag
     3481 tcatatcaat aatgacaata gtaataaatg gtgaggtaaa aaaagtagac aatatatcaa
     3541 aagattataa agataaatta ataagatttc atgttatagc aaacagcaat acagatgaag
     3601 atcaagaact taaactaaaa gttagagatg aagtaataaa atatttacag ccaaagcttc
     3661 aaaattcaaa aagtataaaa gaaagtgaag ctattataaa aaaggaatat agtagtctgg
     3721 aagaaataag taaaaatatt attcttaaaa atggatataa ttacagtgta aaggtaggta
     3781 tacaatatag caatttccct actaaacaat attctaatat agttcttcca gctggtgaat
     3841 ataaagcatt aaagattatc attgggaaag gtgaaggaaa aaactggtgg tgtgttatgt
     3901 tccctccact atgttttgtt gatgaatcta atggagtgat agataaatct acagatgata
     3961 agttgaagga agttttaact gataaagaat ataagttaat aaaacaagat acaccaaaaa
     4021 aaacaagtag agtaaaaatt aagtttaaag tacttgaagt agtcaaggat ttagagaaaa
     4081 aattttaaaa ataagaatgt aaggagtggt tttaatcatg gacaggtgga gtaaactgat
     4141 ggctacacta ttagctttga cttttatatt tatgcctatt aaagaggtat ttgcatatga
     4201 accaacagaa aatattaaga aagtaaacaa acaagaaaaa aatatagcaa agaaagaagt
     4261 aataaattta tctgataatg acttgatgtt attatctaag ttggttgcag gagaagctag
     4321 aggagaaagc tatgagggac aggttgctgt agcagctgta gtaataaata gagtattgga
     4381 ccctagattt ccagacacaa tagaagaagt catatatcaa aaaaatgctt tctcagttgt
     4441 gcttgatggt tcaataaaga tggcaccaac agactcagca cgtaaagcag ctcaggaagc
     4501 tctttatgga actgacccaa ctaataaagc agtatatttt tggaatccag aaatagccac
     4561 ttgcaaatgg ataaatagat tgaatcctta tatgagaata ggaaatcatg tgtttgcaaa
     4621 ataaatttaa atttttaagt agtgaaagga gttgtctttt tgtagaaatt attttctaat
     4681 ttaagatagc tcctttattt tttgtgtaaa ataaactata ataatcattt aggtaataat
     4741 atattaatta tgaatataaa tataaatttt agcgataaat aagttgttgt taaacacaaa
     4801 aatgtaaagt aggtgttgta taaagatgaa caataaacca ataggagttt ttgattcggg
     4861 attaggtgga ttaacagttc taaaagagat aatgaagata ttaccaaatg aggatataat
     4921 atactttgga gatactgcca gaataccata tggttcaaga tccaaagaaa ctataattaa
     4981 atatactttt caagctataa actttttaaa aacaaaaggt gtaaaagcta tagttatagc
     5041 atgtaacact gctactgcaa gaagcttaaa agaagctcaa gaaaaatatg atataccgat
     5101 aattggagtt atagaagcag gagctagaac agctgtaagt tctacaaaaa acaaaattgt
     5161 aggaataata ggaactgaag gaactataag ttcaaaagca tacaacttgg aaatatctaa
     5221 aatagatgag agtatagaaa ttgttaataa agcatgtcct ttatttgtac ctattgttga
     5281 agaaggatgg gcaaatacag aagtggctaa attgacagca aagatatatt tacaagaatt
     5341 gaaagaaaaa aatatagatt ctttagtgtt aggatgtact cattatccta ttttaaagag
     5401 aacaataggt gaagaagttg gagagcatat aaaacttgtt aatccagcta aagagactgc
     5461 aaaggattta aaaaagattt tagaggtgca aaatattata aacaatacag aaattcatgg
     5521 gacttatcaa tattatgtat cagatatacc tgaaaaattt tcagatatag caagagagtt
     5581 cttaaagaaa aaaattgata agattcaaaa agtagaaata caaaaatact agtttatatg
     5641 aagaatctat ggaggaaaaa tcgttgagtg taaaaataag tataaatact agacaatatg
     5701 atgaaaaagg aaatatggac accatagaga tgactgcctt tggtaaaatt ttttataaaa
     5761 atgatggaat atatgttatt tacaaggaaa aagaagaaaa tatagaaata actaatacta
     5821 taaagatact taaaaatcaa gttagtatca aaaagtttgg tgctattaac tcaacaatgc
     5881 tgtttaaatg tggagaaagt agtactacaa agtatgtgac cccacaaggt actttattaa
     5941 ttgatattga tacaagagaa ttagatataa atatacaaga aggggaacac ataaaattga
     6001 aaatagacta taatataaag gtacaagatt tatttttagg taggaataaa atagatatat
     6061 acataggtac taaataataa ctatggctat tttccagaaa ttttataaag gtagtgaaaa
     6121 aactaccttt tatttaattt atttggtatt attatattta tattaaactt taatttctta
     6181 aaattgatac aagggtttag cgttttttta tagaaagtat acttaaaagt gaataaaact
     6241 aagtgtaaga gggataaata tgatatttga taaggtacta agtactataa ataaacataa
     6301 tttaatacaa aaaggcgata aaatagtttt aggtctttct ggaggacctg attcagtttg
     6361 tttattgcat gtactaaata gattaaaaaa agattttaat atagaaatat atgcagcaca
     6421 tttaaaccat caaataagag ggatagaagc tcaaaaagat gcattatatg tatctaaact
     6481 ttgtgaggat atgggaatta tattctttgt aaagtctatt aatgtaccaa aatattgtga
     6541 aaatgaggga ttatcattag aagaaggagc aaggaagcta agatatgaaa tgttttatga
     6601 aattaaggat aagattaaag ccaataaaat agcaataggt cataatctca atgaccaagc
     6661 cgaaactgtt atgatgcgta tcatgagagg aacaggctta aaaggcttaa agggaattga
     6721 ttatattaga gataattgca taattagacc catattagac gtggaaagaa atgagataga
     6781 ggagtattgt gaagcttata atttaaatcc gaggatagat aaaacaaatt tagaaaatat
     6841 atacactaga aataagataa ggttagacct tttaccatat atgaaggata attttaattc
     6901 aaatgtaata gaatctatag tgaggatgag caatagttta aaaagtgata acgattatat
     6961 tgagaaagag gcagaagcta aatttagaga agtttcaaat ataaaagaaa aaggctttgt
     7021 agagataaat ttagacgatt ttgtttgctt acatgatgct atcaaagtta gagttcttag
     7081 aaattccata aaacatatac taggagatac taattttgtt gaccaaagac atatagaaga
     7141 tataatgtct ttagaagata attcaaaagt aaataaaatg ttaactcttc caagaaatat
     7201 atttgtttat agaaaaaaag acagtataat attaacgaat gaggaaattg ttaatgagga
     7261 aattgaattt tattacaatg tacctagtaa tgggtttatt aaaataaaag aattaaaaca
     7321 aattattgag acccaagtaa tgagcataga taggtataag agtatgaaat tagacaattc
     7381 atctaaaggg tttgatttta ataaggtaaa agggggtata gtaataagaa gcagaaggca
     7441 aggtgataag ataaagcttg ctatgggaag taaaaaagtg aaagatttat tcatagattt
     7501 aaaaatccca agagaagaaa gatgtaaaat tcctataatc acagatagtg aaggaataat
     7561 atgtgttgga gattataaaa tcagtgaaaa ttataaaatt gatgaaaaca caaaagaagt
     7621 attaaaaatt aattttaaca aattataggg caaagcaatg tatgaaagga gggcttctat
     7681 attgaataag ttgctaaaag gggcaggttt ttatctactt gtttttataa ttatagtagg
     7741 tatagttcaa ttctcaggta agcctacaga aaaaataaaa gatttaaaat tctctgaagt
     7801 atatagagaa ttaacagatg agaatatatc aagattatac tttgtaaatc aaacttctgt
     7861 agaaggtact ataaaagata caaatacaaa gtttaagtca tatgttccaa cagaagtgat
     7921 gggaaataaa cttgcagatg aggtgttaga ccaagctaag gctgggaaac taacttttgg
     7981 tggtgaagct aagccatcta caccttggtt tgtcgaaatg ttgcctacat tactgttaat
     8041 attcttcatg gtgattattt ggttcgtgtt tatgaatcag tctcaaggtg gaggcggaaa
     8101 ggttatgagt tttggcaaat caaaagctaa ggttcataaa gatgatgaaa aaactagagt
     8161 tacatttaaa gatgtagctg gactagatga ggaaaaagaa gatttgcagg aggtagtaga
     8221 tttcttaaag aatcctaaga aatatattga attgggtgca agaataccaa aaggaatgct
     8281 tatggtagga cctcctggaa ctggtaaaac atatctatca agagcagttg caggagaagc
     8341 aggagttccc tttttcagta taagtggttc tgatttcgtt gagatgtttg ttggggttgg
     8401 tgcttcaaga gtaagagatt tatttgaaca ggctaagaaa agtgctccag ctatcatatt
     8461 catagatgaa attgatgcag ttggtagaaa aagaggtgca ggtcttggtg gaggtcatga
     8521 tgaaagagag caaactctta atcaacttct agttgaaatg gatggatttg gggtaaatca
     8581 aggtataata atcatggcag ctacaaatag accagatata cttgacccag ctttacttag
     8641 accaggaaga tttgacagac aagttgttgt tggtacacca gatgtaaaag gtagagaggc
     8701 tatatttaaa gttcactcaa gaaataaacc attaagtgat gatgtaaaaa tggatgtctt
     8761 ggctagaaga acaccaggat ttactcctgc tgatatagag aacttaatga atgaggctgc
     8821 aatattaaca gctagaaaaa gagaaaagaa aattaagatg gaaactatag aagaagctat
     8881 aacaaaggtt atagcaggtg tggctaaaaa atcgaaagta ataagtgaga aagaaagaag
     8941 acttacagca taccatgaag gagggcatgc agtttgtgcc catgtacttg aagaagtaag
     9001 tcctgttcat caagttacaa tagttccaag aggaagagct ggagggttta caatgcaact
     9061 tcctgttgaa gataagttct atgctacaaa aaatgaaatg aaagaaaata ttgtagtttt
     9121 acttggtggt agagtagcag aagagctagt acttaaggat gtatctacag gtgcttcaaa
     9181 tgacttagaa agagttacag ctactgcaag aagtatggta acaaagtatg gaatgagttc
     9241 taaacttggt ccaatgtcat ttgacagtga tgatgaagta ttcctaggta atagtttttc
     9301 aagtaagaga aattactctg aagaagttgc ttttgagata gaccaagaaa caaagcgtat
     9361 agttgatggt gcatatgata agacaagaag tatattacaa gaaaatatgg atagattaga
     9421 gtatgtagca caagctttac ttatatatga aactttagat gcagaacaat ttgtaaaagc
     9481 atttaataaa gagttacctc tgaatgaaat tgaaaatgca gttacagagg aaaattcttc
     9541 taaagaagtt gaagaacaat taactataaa attagaaaaa gatgaagaag aaagaaacaa
     9601 tgttattgat ataaataaaa atttagaaga taaatctgat aaagataaat agttttaaga
     9661 ccttggtcat tttaagatta ttatctgatg tggattaaat actaaaactg aaagtataat
     9721 attaaattaa taagcaaatt atatttgcat gtattaattt aattgatact ttcagttttt
     9781 tattatttta aaattattta aataaaatgt aaaattatat aaatcatcaa tataaaatat
     9841 aaaacaacca ttataataat taaaaaggaa atttaaaatt aatagtatta aaagtatatt
     9901 aataatgtat aattatttat tagaagaaaa taagtcatga aattatgtca tattagaggt
     9961 gaaatatgcg agataaaata atagagatta tattaaataa taaatctgaa tttatttcag
    10021 gagaagaatt atcaaaacaa ttaggggtgt cacgtgcagc tatatggaaa catatgaaag
    10081 ccttaaaaga agagggatat aatatagaat ctgtaaataa aaaagggtat cgattagcgg
    10141 aaaatccaac tgatttatta agcccacaga atatttacta taaattagat acagagttta
    10201 ttggaaaaaa tattgaacat cttgacacta tagattcaac aaatgaacat gctaaaagga
    10261 tagctataaa tagtgtagat gggactgtga ttttaagtga acatcaagat atggggaaag
    10321 gacgattggg aagaagatgg gattcaaaaa ctcatgaagg aatctggatg agtattatat
    10381 taaaaccaga tatggaacca ttcaaagctc catttataac tttaatagca ggagcaagtg
    10441 taacgaaagc tttaaacaat ctaggagcaa atacattaat aaaatggcca aatgatgtta
    10501 ttttaaatgg aaaaaaaata tgtggtatat taacagagtt atctgctgaa attgaaagaa
    10561 caaattatgt tgttcttgga attggaataa atgttaaaat aatggatttt gaacaagaaa
    10621 tagctgacaa agccacatca ttgtataaag aagggtatat gttatccaga gtagatattg
    10681 ttaggaatgt attgactgaa tttgaaaaat tatatttaga ttatactgta aataattcca
    10741 aagaaaaaac cttaaaaata tgtagagatt attctgcaat tatagataaa aatatatatg
    10801 tattaaaagg agataataga gaactagtga aatgtttaga cataaatgaa gagggaaatt
    10861 tattagttca aagaagtgat ggaagtataa aagaaattat ttcaggtgaa gtttctataa
    10921 gaggagaaaa aggatatgta taataatatt ttggatatag aaggcttaaa ggttgggcag
    10981 gttgaggata gaaatggtct tactgggtgc acagtagtaa tatgtgaaga aggagctact
    11041 tgcggtgttg atgtaagggg ttctgctcca gggactagag aaaccgattt attagaccct
    11101 gtaaatatgg ttcaaaaagt tcatgcagta gttttggctg gaggttctgc atatggtctt
    11161 gaatccactt gtggtgtaag tagatactta gaagaaaaag gaattggctt tgatgtaggt
    11221 gtaggtaaag tgcctatagt tgtaggagca gttttatttg atttaggagt agggagcttt
    11281 aaatgtagac cagatttaaa gatgggttat agagcttgtg aagttgcaaa tactgatatt
    11341 ttaaatcaag gaaattatgg agcaggttgt ggagccactg ttggaaaaat aagaggtcag
    11401 gaatatgcta tgaaaggcgg aataggtagc tattctataa aattagataa tggtctaatt
    11461 gtatctgcat taattgctgt aaatgctctt ggagatgttt atgaaaatgg taaggttata
    11521 gctggtgctt taaatgataa aaagacagaa acaattgata catataaatt aatgaaacaa
    11581 ggtgaaagta aaggtggatt tagtgtagat aatactacaa ttgggataat tgcaacaaat
    11641 gctaagttaa ccaaagctgg atgtaaaaag atatctcaaa tgggacatga tggatatgct
    11701 aagtctattt ttcctatcca tacacctcat gatggagata caatattcac aatatcaaca
    11761 ggagaaatag aagcagatat aacattagta ggttcattgg ctgtagaggt tgtggaaaaa
    11821 agtataataa atgcagtaaa aaaagcggat agtgtagaaa atataatggc atataaagat
    11881 atagtaaaaa aacgagaaat atgatgaaat tagcatattt ttcttgtcaa attgttgaca
    11941 atggcaactc atcttgataa aattattctt gttagagcgg gcatcctaca atggtagctt
    12001 gactcatagt tataagaaaa aaacgaaaaa aattaaaaaa ttaagtagtc cggcatctta
    12061 atgagctgga acggaggtgt attttttatg atgaacacaa gtgcatcagt aagaaaagta
    12121 aatgtaagaa agatgactat aataggagta ctatcagcta tttctattat gctatctatg
    12181 actccattgg gatttattcc agttggacct acaaaagcaa ctataatgca cataccagtt
    12241 attattggag ctattatgga aggaccaata gttggggcag caataggatt tatatttggg
    12301 atatcaagtc tcttaaatgc tataacaaac ccaacagtaa catcttttgt ttttataaat
    12361 ccattagttt caatattacc aagagttatg ataggtgtat tagcttatta tgtatatcag
    12421 ttaataatta aggctacaaa taaggtatac atatcaggtt taattacagg ggcaataggt
    12481 tctctgttaa atacagctgg agttttagga atgatatatg tcttatatgc tgacaagtat
    12541 cttcatgcaa tgggtaaaag tggttcagca ggaaaagtaa taatggctct tgccgcagca
    12601 aatggggtgc cagaagcaat agtaggggct ttagtagtag ctgctgttgc cactgtactt
    12661 aagaaaagca aaaaatagaa agaaggttaa tgacatatgc ttctagtatt tgatgttgga
    12721 aatactaata tggttttagg tatatataaa ggtgacaaat tagttaatta ctggagaatt
    12781 aaaacagata gggaaaaaac gtctgatgaa tatggaatcc tgataagtaa cctatttgat
    12841 tatgataatg tgaatataag tgatattgat gatgttataa tatcatctgt agttccaaat
    12901 gtcatgcatt ctcttgaaaa cttttgtata aagtactgta aaaaacagcc attaatagta
    12961 ggtccaggca taaaaacagg tctaaatata aaatatgata atccaaaaca agttggggca
    13021 gatagaatag ttaatgctgt agcagggata gaaaagtatg gagcaccaag tatacttgtt
    13081 gattttggaa cagcaactac attttgtgct atctctgaaa aaggtgaata tttgggtgga
    13141 acaatagcac caggaataaa aatatctagt gaggcgttat ttcaaagtgc gtctaaatta
    13201 cctagagtag aattagctaa gccaggtatg actatttgta agagtactgt atcagccatg
    13261 caatctggaa taatttatgg atatgttggt ttagttgaca aaataataag tatgatgaag
    13321 aaagaattga attgtgatga tgttaaggtt atagctacag gtggattagc taaactgatt
    13381 gcttcagaga cgaaaagtat agattatgta gatggttttt taacactaga aggattgaga
    13441 ataatatatg aaaaaaacca agaataatta atatacaggg aattgggtta tatatccaat
    13501 tcccttttta tgatagattt ctagctatat gtggtatatt ataatgagga aataagaatt
    13561 taaagttaaa tcacaaaata aaggcaaaaa taggagaaaa acaatgaaaa taggaaattt
    13621 agaattgaaa aataaagttt ttctatcacc tatggcaggt gtaacagacc ttccatttag
    13681 attaatttgt aaagaacagg gatgtgggct tttatataca gaaatgataa atggtaaggc
    13741 actttgctat gatgatgaaa atactaaaaa aatgcttaag atagaagagg aagaacatcc
    13801 tgtagcagtt cagatattcg gttcagaacc agagtttatg ggaagagcag cagagataat
    13861 gaatgattat tcaaatgaga ttctcgatat aaatatgggg tgtccagctc caaaagtagt
    13921 taaaaatgga gatggttcag cacttatgaa aaatcctaag cttgcagaag aggtattgag
    13981 ggcagtagtg aagaactcaa aaaagccagt gactttaaag attcgaaaag gctgggatga
    14041 taatagtgta aatgctgttg aaatagcaaa gatagcagag gattgtggaa taagcgcttt
    14101 agcaatacat ggaagaacta gagaacagtt ttatacaggc aaagcagact gggatataat
    14161 tgcagagatt aagaaaaatt tgagtatacc tgttatagga aatggtgatg tatttacaat
    14221 agaagattca ataaatatgt tagacaaaac tggttgtgat gctataatga taggtagggg
    14281 tgctcaaggt aacccttgga tatttaaaag aataaaccat tatatgaata caggcgagat
    14341 tttgccagag ccaactctta acgaaaaaat aagtactgcc attaagcatt taaaacttgc
    14401 agtagaagaa catggagagt atgtagctgt aagggaaatg agaaaacaca tcgcttggta
    14461 tttaaaagga cttagaaact ctgcaaaatt aagggatgaa attaacaaaa tagaagacta
    14521 tcaagaagtt gtgtcgaaat tggagtacta tatggaagac tccttgacat aaaaataata
    14581 gtgacttata atatagcgca taaattaaaa aaagattata aaatttttaa aatataatta
    14641 ggaaaattcc taagaaattt gtgaaggagt tgtatttata atggaagaaa ataaagagtt
    14701 tttattgaca caagagggat atgataaatt agaagaagaa ttagaaaact taaaggttgt
    14761 aaagagaaaa gaagttgcag agagaataaa agttgctata tcttttggtg atttatctga
    14821 aaatgctgag tatgatgaag ctaaaaagga acaagcacaa gttgaagaaa gaattttaaa
    14881 attagaaaat atggttagaa aagctgttat catagatgaa agcaaaatag accttaatgt
    14941 tgttacaata ggatcaatag ttaaagttaa ggatttagaa tttgatgaag aggttgaata
    15001 tactatagtt ggttcgacag aagcagaccc atatgatggt aaaatatcaa acgaatctcc
    15061 tgtagggaaa gcacttttag gtagagctgc gaaagaagtt gtggaagtgc aagttcctga
    15121 tggagttgct aagtttgaaa tattagaaat aagaagataa tttggaggaa aaaaatgaaa
    15181 aataatcaac aaagcaatga agaagcgcaa attcaagaag accttagtga agtacttcaa
    15241 gtaagaagag ataaactaaa aaaattacaa gagtcaggta gagatccttt taaagaaagt
    15301 agatatgata gaactcatta ttctatggat ataaaagata actttgattc tcttgaaggt
    15361 aaaactacaa aaatagcagg acgtataatg agcaagagaa tacaagggaa agctggcttt
    15421 atagatattc aagaccaaga gggaagaatc caatcttatg taagactaga tgctatagga
    15481 gaggaagaat atagtgtatt ttcaacatat gatattggag atatagttgg aattgaagga
    15541 gaaatcttta aaactaaaaa aggtgaaata tctgtaaagg ctaaatctgt agtattacta
    15601 tgtaaatctt tacaagtttt accagaaaaa tatcatggat taaaagacca agaactaaga
    15661 tatagacaaa gatatgttga cttaatagta aatccagaag taaaaaatgc ttttttaatt
    15721 agaacaaaag cattaaaagc attaagagca tacttagatg atagaggatt tttagaagtt
    15781 gagactccaa tattaaatac tatagcaggt ggggcaaatg ctagaccatt tataactaat
    15841 cataatactt tacatatacc aatgtattta agaatagcaa atgaattgta tttaaaaaga
    15901 cttattgttg gtggatttga taaagtttat gaaatgggaa gaatgtttag aaatgaaggt
    15961 atggatttaa aacataatcc tgaatatact gcaatagaat tatatcaagc atatgcagac
    16021 tatactgata tgatggaaat aacagaaaat gttattgcac atatggctga agttgctaca
    16081 ggaagtatga tagttaacta tcaaggaaca gaaataaact ttacaccacc ttggaaaaga
    16141 atgagtatgg aagattgtgt taaagaatat tctggtgtag atttttctac tataaataca
    16201 gatgaagagg cactagaagt tgctagagaa aaaggtatag agataaaacc tggaatgaga
    16261 agaggagaag taataaatgc tttctttgaa gaatttggag aagataaatt aatccaacca
    16321 acatttataa ctcatcatcc agttgaagta tctccattat ctaagagaaa tgttgaagac
    16381 ccaagaagaa ctgatagatt tgaggcattt gctaataagt gggagttagc taatgcattt
    16441 tctgaactta atgaccctat tgaccaaaaa ggaagattta tagaccaatt gagaaaaaga
    16501 gaattaggtg atgatgaagc ttttgaaatg gatgaagatt tcttaaaagc attagaggta
    16561 ggtctacctc ctacaggagg actaggaata ggtatagata gagtaattat gttattaact
    16621 aactctccat ctataagaga tgtattatta ttcccgacta tgaaacctat tgataacaat
    16681 ccaaataaag aagaagaaaa ctaagaaata ttagcattct actaagtttt aaataaagtt
    16741 tagctattaa attagcaata aatagctaaa ttttgtttaa aatgtcagtg tagaatgctt
    16801 tttatatgct tcaaagattc ttttagatat ttaatttata aattaccaac aaacgttaga
    16861 aattgatatt agtttttgtt gattgagact ttatatttag aaaatatgat tgaaagtaat
    16921 ttattatgaa aatatttaga ataatttatg agaaggtaaa aagaataatt tatgagaata
    16981 ctatatataa aaaattattg ggggaatgtc tgatgtttca agtaattaat tttttatgtt
    17041 tattttgtgt tggatttttg gttcttgatg ttatgatata tttttgtaag gatgcaatgg
    17101 atatttttga gggtacaact aatgttaata aagttaagag tataaatatt tgggcagata
    17161 gagtgagagc taattcatat tcttatgaaa ataaaattgc aaaataggta aaattatata
    17221 tgcatgtatt gtttgtaata tcaagggtta tatctattag ttttaattat atttattaaa
    17281 aaaaccaaaa gttataacct tttttaaaat aaaaaacaaa aaaagtattg acgaaatatt
    17341 tttaag
//
LOCUS       DAEQJM010000071        17252 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.072, whole genome shotgun sequence.
ACCESSION   DAEQJM010000071 DAEQJM010000000
VERSION     DAEQJM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17252
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.072"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(325..849)
                     /locus_tag="KRQ43_003011"
     CDS             complement(325..849)
                     /locus_tag="KRQ43_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH2743355.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(914..1666)
                     /locus_tag="KRQ43_003012"
     CDS             complement(914..1666)
                     /locus_tag="KRQ43_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH2743356.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDISKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1697..2995)
                     /locus_tag="KRQ43_003013"
     CDS             complement(1697..2995)
                     /locus_tag="KRQ43_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HBH2743357.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQQGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREVNVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(3012..5276)
                     /locus_tag="KRQ43_003014"
     CDS             complement(3012..5276)
                     /locus_tag="KRQ43_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HBH2743358.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5531..6349)
                     /locus_tag="KRQ43_003015"
     CDS             complement(5531..6349)
                     /locus_tag="KRQ43_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH2743359.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGIDEKIIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIIL
                     LDEPTAGLDPVSTRSIVDIIKGLNKDNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFVNENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6342..7040)
                     /gene="cbiQ"
                     /locus_tag="KRQ43_003016"
     CDS             complement(6342..7040)
                     /gene="cbiQ"
                     /locus_tag="KRQ43_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HBH2743360.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIKNIFVLSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEIFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKMHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(7043..7327)
                     /locus_tag="KRQ43_003017"
     CDS             complement(7043..7327)
                     /locus_tag="KRQ43_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH2743361.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPDYEPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGVQKGKRS"
     gene            complement(7317..8069)
                     /locus_tag="KRQ43_003018"
     CDS             complement(7317..8069)
                     /locus_tag="KRQ43_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HBH2743362.1"
                     /translation="MKQNIKLGVIAALMLIVLTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLVGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIISFLIFKALKKKDG
                     NNAMPVFLAAAIGDLATYTVTSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8258..8450)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8582..10354)
                     /locus_tag="KRQ43_003019"
     CDS             complement(8582..10354)
                     /locus_tag="KRQ43_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBH2743363.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYNMDKHPALDSMTRRIVNDIRNIDTN
                     QDMMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10368..11297)
                     /locus_tag="KRQ43_003020"
     CDS             complement(10368..11297)
                     /locus_tag="KRQ43_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2743364.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11526..11714
                     /locus_tag="KRQ43_003021"
     CDS             11526..11714
                     /locus_tag="KRQ43_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2743365.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRAKRRKEVQYE"
     gene            11707..12408
                     /locus_tag="KRQ43_003022"
     CDS             11707..12408
                     /locus_tag="KRQ43_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743366.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLLDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSINNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12410..13333
                     /locus_tag="KRQ43_003023"
     CDS             12410..13333
                     /locus_tag="KRQ43_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2743367.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13490..14413
                     /locus_tag="KRQ43_003024"
     CDS             13490..14413
                     /locus_tag="KRQ43_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743368.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGCEKRVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDHTLRLYNTTLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14406..15143
                     /locus_tag="KRQ43_003025"
     CDS             14406..15143
                     /locus_tag="KRQ43_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743369.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFASIALGRRK"
     gene            15154..15927
                     /locus_tag="KRQ43_003026"
     CDS             15154..15927
                     /locus_tag="KRQ43_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743370.1"
                     /translation="MWKLLWAECQKIRRSKIVWITFFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            15943..16095
                     /locus_tag="KRQ43_003027"
     CDS             15943..16095
                     /locus_tag="KRQ43_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743371.1"
                     /translation="MKKIKKLIILIVFLFLFGMLHCYTEWKFNNDPPKGVIERINEWT
                     DKIGLD"
     gene            complement(16468..17076)
                     /locus_tag="KRQ43_003028"
     CDS             complement(16468..17076)
                     /locus_tag="KRQ43_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBH2743372.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5576 a         2986 c         2156 g         6534 t
ORIGIN      
        1 ttataaaaaa ccttattttt attaaataga ataaataaaa taagtttaaa aaatactgaa
       61 ataagtgttt tccacatatt ttatatattt atttaataca ttattattta aaaataaata
      121 tataaacaat cataataaaa tttttttaat aaaactttat tttttagtta aaatcataca
      181 atatatagct ttccacaata caaataaatt aaaaagtgaa atgtatttgt ctaaaaacat
      241 aataacattt cactttatcc tcatttttaa gtaatatata tttttaattt ttatttataa
      301 ctcaatctag tttttatata agttttagtt tttttctaca tctgagtaat ctattccaaa
      361 agtttctaca gtaacagact tcataatttg tggagtttgt ggcttatcag ctgaatctgt
      421 tctaactgat gctatttcat caactgtatc cataccttct atcactctac caaaacctgc
      481 atactgacca tctaagtgtg gtgagttttt atgcattatg aaaaattgag aaccagctga
      541 attaggtgcc atagttctag ccattgatat gactcctctt tcatgtttta aattgttagt
      601 aaatccatta ccactaaatt caccttttat tgagtgacct gggccaccca ttcctgtacc
      661 atttgggcat cctccttgta tcataaatcc tggtattact ctatgaaata ttattccatt
      721 gtaatatcct tcatttacta atgatacaaa gtttttaact gtatttggag ctatatttgg
      781 atataactca attttgattt cttttccatt ttccatttct atagttacta taggattttt
      841 attttccata atttattacc ttccttttca ttagttaaat tacataatta catttattat
      901 attatactct aaattaaagt ctatcaagta tattttttcc tatttcgtat ccttcttgat
      961 aaatagtttt acaaaactca tcatcaaagt taagcgtatc tttaggagca aattgagtat
     1021 taggtctaac tactattatt ttatcttcat catatacttt tttaatatcc tctggcaact
     1081 cataattata ttttgtggat attaaaataa ttttatccac attatcccca attaatggtt
     1141 caattaatgc actcctaatt aaacctccat ctaatttgaa accatcataa attccttctt
     1201 gcacatcttt cacaaattgt tctttaaatc caagagttgc gtttggattt gatggtaaca
     1261 acccactgta tgaaatgctg ataatggctt cattacgagg catttttgat atgtcaacaa
     1321 tcttttctga tactacttta ttatcaactt caacataatt aacataaaag ttcatttctt
     1381 ctatattact atcatctagt tcccttaggt tgtctatagc aggagaatta tccacagtat
     1441 tatttactat ttttacattt ccattctgga tatcttttat atttgtccac attttctcca
     1501 agttatcaac attccctgtg tacaaataat atccatttat tgctcctatt gatgtccctg
     1561 aaatcgaata aaatttattt attcctccat catacaaggc tttaactact cctgcttgat
     1621 aagccccttt tgctcctcca ccttctaaac ataatcctaa tttcatagtc tcatctccaa
     1681 attgtttatc ttatatttat atttcaaaaa acttactaaa tgttttatat atactatagt
     1741 ggtcctcaac atttcctaat tctcttatag agtgcattgc taaaattgga cttcccacat
     1801 ccacagatgg tatatctata tgagtagaag atattggacc tatagtactt cctcctcttt
     1861 catctgacct attaacaaat tcttgatact caacattaac ttctctacat atatttttat
     1921 aaatagctat agaatatcca tcactagtat atgcctgact agcatttatc tttataactg
     1981 gaccttttcc cattattggt ttattagttg ggtcatgctt ttctggaatg tttggatgaa
     2041 tagcatgagc taaatctgat gatatcataa aagatgaata aatagactca aagaatccct
     2101 ctctatcctt acccattgat atgcaaattc tctccaatat atttaacaac atgtttgaat
     2161 ctgcaccttg tttagtagag ctaccaactt cttcattgtc aaatacagcc attacattta
     2221 caccttgttg acctttagta ttaacaagag cattcaaact agcatgtacc attgcaagat
     2281 tatcttgtct cccaatagat ataaattcat cattagcccc tattaaactt cctttttcaa
     2341 attcatataa aaataaatca aaatctataa tatcttccat atttacatct aagttagatg
     2401 ctatttgctt tataagaaaa ttatcttttt ctaatgtatc atttaacatc ccaactaaag
     2461 gtaacatatc tttttgctta ttatatgaat gaccatcatt tatacttcta tttaaatgta
     2521 ttgctagatt tggtattata caaattggct ttttaaagtc tataagcctt tcatttggtt
     2581 ttaatatact atcacctttt aaaactactc taccagctat cccaagaggt ctatccaacc
     2641 atgtacttaa tattgctcct ccatagcatt ctgtatttaa cttcaaataa gatttttcag
     2701 cttctatttc tgcatttggt ttaatactaa atgtaggaga atctgaatga gagcctatta
     2761 ttctaaatcc atctctttct atatcttctg aatttactac aaaagctact atagctgata
     2821 gattcttagt aacataatac tttccaccaa ctcttagatt ccatctttga ttcaaaacta
     2881 attcttcaaa tccattttta tctaagattt ccttagtact ctcgactgca tgaaaagacg
     2941 acggactatc atatatgaag tctattaagt ttttagcaaa gtttatacta tccattcctc
     3001 atttacctcc attataaaat atttagtgtt gtatattctt tatttatttt tttaattccc
     3061 tgttggtcaa aagctatagt aacatctgta ccaattatag aaaccactgt cccaacccca
     3121 aatttaggat gatgtacctt agaaccaagt tttatatcat ctggattagt ttctttatta
     3181 gaatctttta ttgtagcatt aactttatct gcaactttag atttgcttat agtactcata
     3241 tactttttag tatatttatc taacatatta taacttgctt tagaatagct tagttctttt
     3301 tttactttgt acaatctttc tatacattct tctggcagtt cttccataaa tcttgaagct
     3361 attgcaacat ttgttttacc atataatgtt ctcttctctg tcaatgacat atatagctct
     3421 tctttagctc tagttatacc aacataacaa agtcttctct cttcttctat ttgtgaatca
     3481 ctcatagatt ttatagctct tgatatagga aataaccctt cttccatacc tgttaaaaac
     3541 acaacaggga actctaaacc tttggatgta tgaattgtca taagcgaaac cctatcattg
     3601 tcttcttcat catttgattc agatgtaagt gctatacttg ttaggaatgt ctctaagtct
     3661 ttattttcat aagtatcatc attactactt tcaaactcca aagctataga aataaattct
     3721 ctcaaattat caattctgtc ttgagcttct tcacctttgc ctgttaaatc tttttcattt
     3781 ttatttctta tctctacaag ctcgtccata tatcctgtag tatccaagac tttttctata
     3841 agtttgctaa caggataaac ttcttttata gttctaagag tccctataat atcaacaaat
     3901 ccacttatac ttgcccttgc cttagtagat atatctgaat ttgtttctat atcaattaat
     3961 actgagtata tactttcctg ttttaagtta gctctatctt caattttttc tatagttcta
     4021 agccctatac ctcttctagg aacatttata atccttttta tagatatatc atcttgtgga
     4081 ttttgaataa ctcttaaata cgccaacaaa tcctttattt cttttctctc gtagaatttt
     4141 gtaccaccat atatattgta tggaatttga cttctattta aagcgtcctc tacaggtctt
     4201 gcctgtgcat ttgctctata aagtactgca aaatccttat aaggtctatt ttcttttcta
     4261 gctatttgtg caattgaatc agcaatgaaa tcagcctctt ctatttcgct accagttaat
     4321 tgtatcttta taagttctcc ttcttttttt tcactccaaa gcttttttct ttttctttct
     4381 atattattag atataacttt attagctgca tctaatatca cttgtgtaga cctataattt
     4441 tgttctaact ttacaacatg tacattgtca taatctttct caaattcaag tatgtttctt
     4501 atatctgcgc ctctccatcc ataaatactt tggtcatcat ctccaacaac acaaatattt
     4561 tgatgttctc ttgctaataa ttttatcaat tcatattgag ctttacttgt atcttggtac
     4621 tcatctacca ttatgtatct aaatctactt ctgtaatatg ctaatacttc atcattagcc
     4681 ttgaaaagtt ctacagtttt aagtattaaa tcatcaaagt caagtgcact atttcttttt
     4741 aaacggtctt gatataacgc ataaatatct gcaatcttaa ccattctatt atctgccatg
     4801 ttgatatctt taaactgctt tggagtataa agtttgtctt ttgctcctga aattgcactt
     4861 ataactgctt ttggttcaaa cactttatca cttaaattta attcttttag acagtcttta
     4921 accaatgtaa cttggtctgc tgaatcataa attacaaaac ttctattgta accaatctta
     4981 tttatatctt ttcttagtat acgaacacag caagaatgga atgtacttat ccacatatcc
     5041 ttagtttcag gacctatatt ttgttcaact ctctctctca tttcatttgc agctttgttt
     5101 gtaaatgtta tagctaatat atttggtgct tgtacacctt tatcttctat aagatatgct
     5161 attcttgttg ttaatacctt agttttacct gaaccagcac cagccagtat aagtactgga
     5221 ccttcagtct tttctactgc ttctctttga gcaggattta atgtatctaa attcatattt
     5281 ctcctcctgt taacagccat aaatatattt taatctaaaa tatgaattac ttcaaattat
     5341 aattatgtat tatattaata gattatttcc aatatattac aattaaataa catttttcca
     5401 tataatttat ttaattgttt aataaaaaaa ataaccttat gatttgggga atcataaggc
     5461 acctttaagg ggtctaggtt aagggttatt atatataaat ctattttttt aaaataggtt
     5521 tagggcttaa ttatttattt gtattaagtt ctctttcctt ccaatactta tacaaatctt
     5581 cttctttctt aaataagggt aaattcatat ttctatgtac ttttactaac catggggatt
     5641 ctaggccagc ttgtataatg ttattttcat ttacaaatac attttctgcc tttccttcat
     5701 caattaaaat ccccttatcc aatacatata tataatcgca tatttcatac attaaattca
     5761 tatcatgact ggatattact atttttatat tatctttatt caatcccttt attatatcta
     5821 caatagacct agtacttact gggtctaaac cagctgtagg ctcatcaagc aatataattt
     5881 cattttccat tgctataact gatgctatcg ctaccctttt tttctgacca taacttaaaa
     5941 aatgtactgg tctatctata aaatctattc cattaacagc tactagagct ttgtttattc
     6001 tctctttaat tattttttca tctataccaa tatttctcat tgcaaaggct atatcatcat
     6061 atacttttga ataaaaaatt tgtttttctg ggtcttggaa cacaatacct acattttttc
     6121 taaggttgta taaacttctc ttatcatatt ttaacttttc ttctttaaaa agaatttctc
     6181 cagatgtagg ctttaatata cccattaaat tcataaataa tgttgatttt cctgaaccat
     6241 ttgaacctat tatacctata acatttccct ttgaaaaatc catattaata tttaatagtg
     6301 cattggtatt cttttcatat tgataagtta aattatttat tttaaacatc attatcccct
     6361 actatgtgaa atttaccatc atacaatttt atgtctaatg atatacacat atcatcatac
     6421 cttgtcataa gtcttttgta cagcatactg ccaagaattc ctaatgattt atatgaagtt
     6481 tttaaattta tgtacccaaa tcttagttct tgtgacttat atatttctga aaattcttct
     6541 aaaaatatga atataaacct atatattaac attgatagct caacaaaagt atcaggcaaa
     6601 tgcatttttt taaagaagaa tattaattga ttaaaaggtg ttgtaagtat acaaaagtat
     6661 acacaagtca aacaagacat agctctaaat aacacatgaa tagacatgtc aatagatgct
     6721 tttgatattc ctacattgaa actaaaaatt tcaaaactat ataataagtc tgccttatta
     6781 aaagatatat ttacaagagt tattcctata ctaagaaata aaaagtacat tggtattctg
     6841 agtaatttta aataattctt taaatctatt ccagctacac aaacaactag aatactcatt
     6901 aaaatcataa ttccacttaa aacaaatata ttttttatta ccatagaagc aatcagaaag
     6961 attactccta tggctacttt tttatttgga tttactttac ttaatctatt tgtatatgca
     7021 tatttatcaa ttataagcat aattaacttc tctttccttt ttgaacacct aatatgtacc
     7081 ctattacacc agcacctaac gctgcttgtg cagagaataa taaactttct atttctccac
     7141 ttggtggctc atatgggcta ctaaaccatg gttcataatc tggatttatc ttagtaattt
     7201 cactctcagc ttgaccatct gctcctccat attcagctcc cgaattaaca agtaatggga
     7261 atatgataag agctactact aataaaagta gtaatatatt agttttcgtc tttgttttag
     7321 cactcattag ctttaactcc tttatcatta ttttctagta tgcttttttc tccattttct
     7381 gtaattaaat tatatacaat tacagtaaga ataccctctg ctattgctat tggtatttga
     7441 gtcataaaga aaattcctaa aaacttaatt gctgaagcca tcactccacc tgatgggtct
     7501 gggaaagcca gtgctaactg tatcgaagtt actgtatatg tagccaaatc tcctattgct
     7561 gctgcaagaa atactggcat tgcattattt ccgtcttttt tctttaatgc tttaaatatt
     7621 aagaatgata taattggtcc tataatagcc attgaaaaag cattagctcc taaagtagtt
     7681 attcctccat gtgccaatag taatgcttgg aatattagaa ctatagttcc aagaacaaac
     7741 attacacttg gtccaaacat tattgctcca agacctactc cagtaggatg tgaacaactt
     7801 cctgttactg aaggtatctt tagtgctgac aatacaaata caaatgctcc acacagcgct
     7861 aataatactt tctttttagg gtcttgcttt actatttttc ctattgattt tagtcctact
     7921 aaaaaaaatg gtataaatat aactccccat gctatagacc attttactgg taagtatcct
     7981 tccattatgt gcattgcatt cgatgtaact ggagttaaaa cgattaacat aagtgcagct
     8041 ataaccccta atttgatatt ttgtttcatt ttactatccc ctctctccct ttctaataat
     8101 taaaatataa ataatatatg tctgatttat tttaaaaata aaaataaaaa agcctaactc
     8161 gatggctagg cttctaattt tcgataatcc aaatacaaac acataaaatg aacatatctg
     8221 tataattatt ataagaaact ttctccatcc ccgaagaaat tactttaata ttttaggcag
     8281 gtctcctgac ttagcttctt cctactcctc ttccttccca tgagatataa aaaatatcat
     8341 catagtggct aacaaaagtt tcgtctgcat cacagtagcg ggggctgtaa aggaatttaa
     8401 cctttttccc tattaatctt gcttaaagaa cctataatat tatatattta atttttaaat
     8461 tattcttaaa tcattttcta tataaatcat tgtatacctt ttctgtgaaa atttctacat
     8521 tttttataaa ttttattcat ttttatattt ttatgtatat aaattctttt ttgtaagttt
     8581 attaatttct aattatcttc tttaaataca ttgaaactac atcagaaaat ctagttatat
     8641 ctcttgaata tataaaatca tttccatata ttaatctttc agcttcaagt tctgattctt
     8701 ttcctgtaaa tactcctagt actaatatat tttgctttct agcttttctc acttcattgg
     8761 ctgtatctct caaaccaact atacccctat aagccttttc tcctcttaat gttctctcac
     8821 tactttttcc tatctttaca tcatttggtc ttccatcgct gagaactatc aggattttat
     8881 tttcttcatc tctatttatt agaccactac atatagattt tattgccaaa ccatctctat
     8941 tattaccagc acaaaaatat tcaaatatat tttcactatt ttttatacta tcatcataat
     9001 ctttaaatct ttttaatatt gtatagtcta aaaaactaga aaatcccatc actctatttg
     9061 gtatgccaac ttctgttaga gcatttgcaa ttatgtaagc ttgaattgcc acatttccct
     9121 gatttctact ttgagagcca cttgcatcca ataatatatc aataacgtat ttcccttttt
     9181 cattttctat atctttataa aatattttat tattattact tctaccaact ctccaagctc
     9241 tatttgctaa tatagtacca caatcagaat atactctact tttagcattt tcttctatta
     9301 aaattcttga cagactttct tttaatctct ttatttgctg tctatacatt ctagcatgtt
     9361 ctctaaattt tcctaaatta ttttcttttt gtcttgttac atattttagt tgaaatacat
     9421 tattacactc acttctaaga actccatctg taaagtgtat tctacaacct tcatgaacat
     9481 ttctacaatt ttgtgtctca atttttttaa tttcaccttt actcaaataa gtttttccat
     9541 aataatgttc tatttttgaa tatatcttat ttgcagtgtc ttcatcaaca tatataactc
     9601 ggtctgctga attgctacat ttagaatcat caaaatcccc tacaccttct acaagcatgg
     9661 atgaagatat tgaatctata tcactttcaa taatattttc ttcttcatca ctataaagtt
     9721 cttcatacat gaaatcagca aatgtatcaa aatttacttc tacactttct acattatttt
     9781 catcaataag actattttct tctccattta atatgtattc gaaataagtt aaatatataa
     9841 catctaatgc ttttaaaatc tccatcatat cttgattggt atctatattt cttatatcat
     9901 taactattct tctagtcata ctatctaatg ctgggtgctt gtccatatta taaagtacaa
     9961 atgtgtattt aattttatcc ataatattat cattgtgtat tttggtaaaa cgtgaaacaa
    10021 tatctttata agcatttctt cttatgtctt ctatccctgg cctatcttta atgacctttt
    10081 cttcaactat tgtatttaat ataacttgaa ttagacccag tataatatct ttgttgtatc
    10141 cttttcttat tctatttgta agatattttt taactatatc ccaatctaca tactttcttc
    10201 tagcacctgc aattattgca aaatatagac ctatttcttt tgaagagtaa tctttttctg
    10261 atatatctat actttcattg taatcaccag ctattgtcca tgataagtta ttagctctat
    10321 tttcaaattc ataatcatca tatatccatt tcataatctc acctatatta aatatgactt
    10381 attggaaata catctatact ctcccattta ttaggtattc tagttttaat tacatctcca
    10441 accatttctt tctcatatac atcaaaagtc tttcctgtaa gtcccatatt aattgcaaga
    10501 gttggtttta atcctcttct tatagtctta agagatgcca taagaccacg taaatcaata
    10561 gctttactag atatctctcc attttgagac ttcaattgta aatctaaaaa tattcctgca
    10621 aagtgtatta atttttcttc atcagcatct gaaaattcat tttttaaaat catcattaac
    10681 ttatcttctt ctataggagg aatatctatt accataaatc tagataccag tgcttcatta
    10741 agttcttttg ttcctgcata ttcataattc atagtcccaa taaatcttgt tgctggatgt
    10801 agattgactc tctcataccc aggtacatca attattcttc tatagtctaa agctgaatgt
    10861 accacaacta tagcatcatt ttttgccata ttaatttcat caaatactcc aaaacctcca
    10921 ttaatagcac actcataaac tgagcctctt ctaagtttaa cttcattgtc tataaatgta
    10981 tctgtaccta taagtgttga actgtctgta tttatatgaa atgatgtatt ccactgaggt
    11041 ctattaaata tttcccctag attatcagca agtaaatttt ttcccgttgc ctttggtccc
    11101 gataataata tattttcttc ttctaaaata gctgctatac acatagacaa gatatcttta
    11161 ccataaaaat aagttttaga ctttgttact ctgtattcta aatctttttc taaaccataa
    11221 taatttctaa aatacagtac atcttcaata agtttttcat ctaccccttg cacccttaga
    11281 ttatctatta tatccatatt tttacccctt ttatataaat agtatttgtt tcatttctta
    11341 tcaccatttt agcataaaag gatataagct aaaattgatt ttttaatctc ccccatttta
    11401 agtaaaacca tgcaccattt tatcactaca aaattaagag tactacttac tgatatttct
    11461 tgattttgtt cgtctatacg tatataatat atgctgataa attatgagga aaggatgatt
    11521 gaaatatgga atatatgtct tgcccagaag tagcaaaaaa atggggcatt tctgaaagaa
    11581 gagtacaaaa actatgtgaa gaaagtcgca taccaggagt ttcaaaactc gggtatatgt
    11641 ggctgatacc aaagaacgca gaaaagcctg ttgatggtag agcgaaaaga agaaaggaag
    11701 tacaatatga atagcgtttt gattatagat gatgacaaag aactttgtgc tcttatgaaa
    11761 aaatgtgttg agcaagaaaa tttatctgct attactgcac attgtggtgc agaaggtcta
    11821 catttgctcg ataaaaatag acacacactc tctcttgtaa ttttagacat aatgatgcca
    11881 gatatagacg gttttcaagt tctgaaaaaa attagagaaa caagtaatat tccagtaatt
    11941 atgcttactg ctaaaaatga cgaggatgat aaagtttccg gactacgttt aggtgctgac
    12001 gattacctaa caaaaccgtt cagcataaac gaacttatgg ctcgtgtcaa ttctcttatt
    12061 cgtcggtata ctatgttaaa ccctgctttt ataacagaca cagattgcat aataataaat
    12121 ggcatgatta ttgacaagac aaaccgaatt gtttctatca ataatattcc tgttcaactt
    12181 acaagcaaag aatttgattt acttgctttt ctggcttcta ataagggacg ggtatttacc
    12241 aaaaaacaga tttatacaca agtatgggaa gaagaatatg cttttgacga tagtaacatc
    12301 atgtctttca tcagtaaatt gagaaaaaag attgaaccag accccaacca tccattttat
    12361 attttgacag ttcgtggtgt cggttatcgt tttaataagg aggcttaaca tgaatacaag
    12421 tgtctatcta cttttgatat tggctcttag cctgattatt atagcgtacc ttgtttctgt
    12481 cctgctacgt gtccgaatac aacttacact tataaaagat gctttagagg atataaaaaa
    12541 tggaaacctt aatcgccgta ttttaacaga tgaaaacgac attacaaaac aaatttgcta
    12601 tgatattaac gaaatagcaa tcaatagcca atttcaactt attcagcaaa aacaatcaga
    12661 acaagcctac aaacagctaa tgacaagtct ctcccatgat gtaaaaactc cacttgcttc
    12721 tttggtcggt tatttggaag cagtagaaag taaaattgtt gtaggagagg aaaaagacga
    12781 gtatatccat gttgcgtcta ataaggctca ttacttaaag aattttgtag aaaatctatt
    12841 tgaatgggta aaattggatt ctaaggaaca agtttttcat tttgatattt ttgacttgaa
    12901 tgaattatcc cgtaatatta tatctgattg gatacctgtt ttagaaagca gtcattttga
    12961 atatgaattt gatataccag aaatagagta cttcttacgt atagacgcaa atgcatatac
    13021 ccgtatcatt aataacctat tacaaaatat tattacccat agtagtggca acaaaatgac
    13081 attgagaatt tttgaaaaca aagagcaagc tcaaattata ataacagata atgggaaagg
    13141 tatatcttca gacaatctcc cacatatttt tgaaaggttg taccaatgcg accattcacg
    13201 agcttcaaag ggaaatggtt taggcttggc gattgcaaag gaacttatta acgctcataa
    13261 gggaaatatt accgccaaca gcactcccgg tatgggaaca gaatttacaa tattgcttcc
    13321 taaagccctg taaaagtacg aggctttctt actctaaaac aagataaaag caagattatg
    13381 gcaaggtttt ggcaaggttc atgttttata attctaattg tagttgattt tgacgttgta
    13441 tcaactatct tttgtagaaa caaatttatt aaaagtgagg aaattatata tgaatgattt
    13501 tgtgattgaa acaaagcaac ttacaaaaat ttatgggaat caaacagtag ttgacaaagt
    13561 caatctccat gtaaaaaaag gccgaatata tggtctgtta ggacgcaacg gagctgggaa
    13621 aaccacaatt atgaaaatga ttttaggatt gacttcaatc acgtatggcg aggtagatgt
    13681 atttggagag aatattaagg gatgtgaaaa acgagtatat ccccgtatcg gtgcaattat
    13741 cgaaacgcca ggattttatc ctaatctgac aggaacggag aacttggaga tttttgcaaa
    13801 acttcgtggt acagccgccc ctaattctgt aaaaagagca ttggagattg taggcttacc
    13861 ttataaaaat aaaaagctgt ttagtaaata ttcacttggc atgaaacagc gacttggtat
    13921 tgccaacgct atcctgcatg acccggaact gttagtttta gatgagccaa ccaatggact
    13981 tgaccctatt ggtattgcgg agatgagaaa gtttattagg gacttgagcg ttgagcatgg
    14041 aaagacaatt cttatctcca gtcatattct ttcagaaatc tcattgttgg ctgatgatat
    14101 tggaattatc gaccacggtg ttcttttgga agaaagtagt atgagtgaac tagaaaagaa
    14161 aaacagtaaa tatatcctgc tacaagtttc agatattcca aagacatcac ttattttaga
    14221 gcgtcaattt aacacgaagg attattccgt tcaagatgac cacactttac gcctttataa
    14281 cactactctg gatatgggtg aaatcaataa agcacttgta atgcagaatg taactgttat
    14341 tagttctcaa ctttgtaatg atactttaga ggactacttt aaaaaaatca caggaggaga
    14401 gggcattgct taaacttatt caaacagaat ttcttaaact gcgtcgtagg aaacttattt
    14461 ggctgatgtt gttgtctgct ctcattatgc cgtttttcgc actactatac ttcaattatt
    14521 ttggtaaaac aggtgttgag ccaacaaagt tttataaatg gtctgcattt ggttatacac
    14581 tttggattat tttgcccgtt gttttgggta tattttgcac catgcttata cacgaagaaa
    14641 accagtatga tatgctcaaa cagctttgga ttgtacctat tagtaaaatg ggatactttt
    14701 ttagtaaatt tttcgttgtt ttgatttact ctatttgttt tatgctgatt acagccgttg
    14761 cttctgtgtt atttagtgta ctttctggat atgtcgtatt tagctgggca agcattttat
    14821 atttgttgaa aaaatgttta gaaattggtg taatcactgc ttttgtaatg ttgccgattt
    14881 tggcaatcgc tacatctcaa aaaggataca ttctcccaat ttgtatcaca ttggtatatg
    14941 ccttttccgg ttttgttata atgacaataa atatgtattt acacccatta tccagtatgg
    15001 gagttattat catgagaaat aaagacattc caggtcttat attttcacag gaaattaatg
    15061 tcccattagc atttctttgt atttgtattt ggagtattgt atcagtattg tttgcaagca
    15121 ttgcactagg aagaagaaag tgaggtgtag ataatgtgga aattactttg ggctgaatgt
    15181 caaaaaattc gtcgttcaaa aattgtttgg attacatttt ttgcatccat tatgatagca
    15241 gtcatagttt ttgcaggagg gcaggatgta tataatgacc cagatttaca ttatggctta
    15301 aagagcgttt atgacggttc acggtatata gacaatgcag gttggtatat ggacgcggta
    15361 caaccttggt caactttttt tgttcttcct gctgtcattg ccctattagg aagctatatt
    15421 atttgtcgtg aagaagagga ggacactatt aaatccctgc gtcttattcc cataaatgaa
    15481 acaaaattaa ccatagcaaa aatgattatt acttttatat tcagtatact tctttatttg
    15541 ttactcttta ctataacatt tttgactgaa tccgttttac atttttccga tttatcgaca
    15601 aaactggttt taagttgcat gaaagagtat tttcttgatg gcataggtgt attctttgca
    15661 atttctccca ttattgcctt ggtatcgcgc atgaaaaaag gatattggct tgcattagta
    15721 ttcacagaag tttattctat tgctggacta tttgcgggta tgtcaaatgt cttacaaacc
    15781 ttttttccta ttgcagcaat atttaatatt tctggatact atataactac tggagaaaaa
    15841 attatgggga gtatcataag tttattactt tgtgcctgcc tttctgcatt tatactgaaa
    15901 gggctaaaac acaatgaaaa aaattgaaat aggtatatca aaatgaaaaa gataaaaaaa
    15961 ctgattattc taattgtatt cttgtttctt tttggcatgt tacactgtta tactgaatgg
    16021 aaattcaaca atgacccacc taaaggggta atagaaagaa taaatgagtg gactgataag
    16081 attggactgg attagtaact tatgttaatt atagtgaatg taatattagc aagttattgt
    16141 ttcgtatttt aatactataa ctttaaatat ttggttttaa tcttccgaac gaatataaaa
    16201 aaactgtcac agaggcaaca tatttttgaa tatttataaa gtggtagttt tgattttcaa
    16261 agctgccgcc ttttcttcta tataagcaaa cttatcctca acaaagtgta aaacatggta
    16321 cattttaaga aaaaagtacc acagacacaa gcaataaaag aaacgccgag aacctacaaa
    16381 aacgtagtgc ttatgcagat ttacgacgcc ttctattttc tcaaccgtct taatgacctt
    16441 gtacaaaaga aatttttcta atatttttta taatcttatc ttgtgatgtt ttttatgtat
    16501 aaatgactta ataacaaatc caataaaaat tatggatatt ggtataatta gaacgaggaa
    16561 tttataatca ttataatgtg acattattct tacccaactc tcagaaaaaa tatatcctat
    16621 actgattaat gaagtattcc atatggttat tcccacgata gatgatatta caaaagttat
    16681 aatattttga cctgctatac ctgctataaa agatatgtat gttctacata aagggattaa
    16741 tctacataca caaacagaaa tagaagagta tttattaaaa taatcttgag atgcaaatat
    16801 tcctttcttt gcctttggac atatctctat tattttattt atgatagatt tacctcccca
    16861 atttcccact gtataacaaa atatcgaacc aagtatacct gcaattatac ttaaaattaa
    16921 aattgtcaga aatccaaaat gatttcttgc agcaattgct ccacataaag gtaaaacaac
    16981 ttcgctaggt aatggaaaac aagcatactc aatcataatt aatacaaata cagagattaa
    17041 tccatattgt aaaataaaac tattgattac agacacttac ttatctatct cctttcttat
    17101 ttaaaggttt taagggtaca tattctaagg attctcaccc tatatttaaa gaatcaatct
    17161 ctttaaacta ttatatgtat ttacacaaag catttataac atactttaaa aatagtacct
    17221 taaaataaga aacttaataa ataaaaaaag at
//
LOCUS       DAEQJM010000072        17188 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.073, whole genome shotgun sequence.
ACCESSION   DAEQJM010000072 DAEQJM010000000
VERSION     DAEQJM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17188
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.073"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            55..258
                     /locus_tag="KRQ43_003029"
     CDS             55..258
                     /locus_tag="KRQ43_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2743373.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
     gene            422..1576
                     /locus_tag="KRQ43_003030"
     CDS             422..1576
                     /locus_tag="KRQ43_003030"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBH2743374.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELVNITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFRVEQENIDVVVHPQSIIHSMVQYADSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            1589..2593
                     /gene="rseP"
                     /locus_tag="KRQ43_003031"
     CDS             1589..2593
                     /gene="rseP"
                     /locus_tag="KRQ43_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBH2743375.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSNKVVNVTPKNNNGKYEIGIQPQREKDFLASIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            2776..3831
                     /gene="ispG"
                     /locus_tag="KRQ43_003032"
                     /gene_synonym="gcpE"
     CDS             2776..3831
                     /gene="ispG"
                     /locus_tag="KRQ43_003032"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBH2743376.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSRERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKHGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            4179..5003
                     /locus_tag="KRQ43_003033"
     CDS             4179..5003
                     /locus_tag="KRQ43_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743377.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLASTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSIWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(5476..6599)
                     /locus_tag="KRQ43_003034"
                     /pseudo
     CDS             complement(5476..6599)
                     /locus_tag="KRQ43_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
     gene            6796..7020
                     /locus_tag="KRQ43_003035"
     CDS             6796..7020
                     /locus_tag="KRQ43_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743378.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            7073..7597
                     /locus_tag="KRQ43_003036"
     CDS             7073..7597
                     /locus_tag="KRQ43_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2743379.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(7702..7848)
                     /locus_tag="KRQ43_003037"
     CDS             complement(7702..7848)
                     /locus_tag="KRQ43_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743380.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(7987..8913)
                     /locus_tag="KRQ43_003038"
     CDS             complement(7987..8913)
                     /locus_tag="KRQ43_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH2743381.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            9104..10975
                     /locus_tag="KRQ43_003039"
     CDS             9104..10975
                     /locus_tag="KRQ43_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBH2743382.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNASCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            complement(11067..12002)
                     /locus_tag="KRQ43_003040"
     CDS             complement(11067..12002)
                     /locus_tag="KRQ43_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBH2743383.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            12522..13034
                     /locus_tag="KRQ43_003041"
     CDS             12522..13034
                     /locus_tag="KRQ43_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBH2743384.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKIYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            complement(13189..14250)
                     /locus_tag="KRQ43_003042"
     CDS             complement(13189..14250)
                     /locus_tag="KRQ43_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HBH2743385.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(14374..15267)
                     /locus_tag="KRQ43_003043"
     CDS             complement(14374..15267)
                     /locus_tag="KRQ43_003043"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBH2743386.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIHSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQNYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            complement(15277..16758)
                     /locus_tag="KRQ43_003044"
     CDS             complement(15277..16758)
                     /locus_tag="KRQ43_003044"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBH2743387.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISSDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKKFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     misc_binding    complement(16866..17097)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         6550 a         2055 c         2687 g         5896 t
ORIGIN      
        1 aaaattttcc aaaatagata aaatgtgata gaatatattt tgcgaggtga taacatgatt
       61 tcatacgctc cattatggaa attgttaatt gacagaaaaa taaagaaaat ggaatttgta
      121 aatatatcag gtataagtat ttctgtttta ggcagactag gaaatgataa atctgtttct
      181 atggatacaa tggagaagat atgtttagca ctagactgta aaatagaaga tgttgtggaa
      241 ataaaaaagg gcatttaata atactagaat attttataat attccacaag atacaaaaaa
      301 taatagatta attttaatct gtggaataat atatgaaatt tctatgaata gtaaaaataa
      361 ttgttttagt agtgttataa tgttttgaca gggtatattt attattagaa aggattatta
      421 tatgaaaaag atatcaattt taggttctac aggctctata ggtaaacaaa ctttggatgt
      481 ggttagagaa catagagata agtttgagat agttgcaata tcagctaaca gtaatattga
      541 attattgcta gaacaaatag tagagtttaa acctaaatat gtaacagttt ttgaggaaaa
      601 taaggcattg aaattaaaag aaatgttgcc taaaaatata gaaatagaag ttttagcagg
      661 aatggaagga ttaaaaataa tatcatcact tgatgaagtg gatgtccttt taactgctgt
      721 agtaggtatg ataggattag tcccaactct ttgtgctata aagaagggaa tagacatagc
      781 attagcgaat aaagaaacgt tggtaactgc tggtgaactt gtaatgaaag aagcagaaaa
      841 atacaatgta aatattcttc ctgttgatag tgaacatagt gctatatttc aatgtctaaa
      901 tggagaaaat aaaaaaaata tagaaaagat aatacttaca gcatctggtg gtccatttag
      961 aggaaagaaa aagggagaac ttgtaaatat aactaaaaat gaagctttga agcatccaaa
     1021 ttggagtatg ggaagaaaaa taagtattga ttcttcaacg cttatgaata aaggacttga
     1081 agtgatagaa gctagatggt tgtttagggt agaacaagaa aatatagatg tagtagttca
     1141 cccacaaagc ataattcatt caatggtgca gtatgcagat agctcaataa ttgctcaatt
     1201 agggtgtcca gatatgagac taccaataca gtatgctctt acatatccag atagaatgga
     1261 aagtagcttt gaaagaatga atttttcaaa atttagtact ttaacttttg aagaaccaga
     1321 tttagaaact tttccatgtt taaaattggc ctatgagtgt ttaaaaatgg gaggaactta
     1381 ttcttctgtt ttaaattcag caaatgaagt tttagtaagt gaatttttag aggataaaat
     1441 tggtttttat gacataccat attacataga gaagacttta gaagttcata gtagcataag
     1501 cgaaccaaca ttagaagaaa tcttagaaac agatagatgg agtagagctt atgttgcaaa
     1561 tctgataaaa aaataggaag gtgaatttat gactataata gccgcattaa tactatttag
     1621 tataattgta ttaatacatg agttaggaca ttttatattt gcaaaaagaa gtggtatcaa
     1681 agtaaatgag ttttctatag gtatggggcc taagatatat agtgtaaaaa aagatacaga
     1741 gtattctata agagcacttc caattggtgg atatgtcagc atggaaggtg aagatgaaga
     1801 acaaataagt ccaaattctt ttggaaacaa gtctatatta caaagattta gtactattgt
     1861 agcaggacca atattcaata taatattagc agcaatactt ttagttccag tatttttgta
     1921 tataggttct ccaacgacta aattaggaaa gataatgcca gatactcctg cacaggctgt
     1981 agggcttcaa gtaggagata agataaataa aattaatggt aattctgtta agacttggga
     2041 tgaagttgca aatataataa acacttcttc tggtggagaa ttaaaactta gtataactag
     2101 agatggaagt aataaagttg taaatgtaac acctaaaaat aacaatggaa agtatgaaat
     2161 agggattcaa ccacaaagag aaaaagactt tttggcgtca atagtaaatg catgtaaaac
     2221 tactgtagat atgacaaaac agatgttaac atttctaggt caaatgatta caggacgtgt
     2281 accaggaggg attggcaatg ctgtagcagg accagtaggt gttattggta tggtatcaga
     2341 tgctgctcgt acaggcatca taaatgtagt gtatttagca gctgtcataa gcttaaattt
     2401 aggtatagta aatctattac caataccagc acttgatgga tggagaatac ttatgctatt
     2461 actagaagct gttagaggtg gtaaaaaact cgacccaaac aaagaaggca tgataaatgt
     2521 tgttggtttt ggagctttaa tgttatttat gctttttatc acatataaag atatattaag
     2581 attatttcaa tgatttagtt ttttagagat tttaagaaaa taggctatgt agttttaaat
     2641 aagaataaat taatttttat gtatgaaatt tattcttatt taactagata gctttttaat
     2701 ttataatata catgtaggtt ataatatttt actatttaaa gagattcaat ataaaataat
     2761 atatagaggt ggaatatgag ttacgagaga agaaagacga gagaagtaag tgtaggaact
     2821 gtaaaaatag gaggagaaaa tcctataagt atacaatcta tgacaaatac tgatacaaga
     2881 gatgcagatg ctacaatagc tcaaataaag agactagagg aagctggttg tgatatagtt
     2941 agagttgctg ttcctgatat taaagctgct aagaatatag caaagataaa gtctagtgta
     3001 aatataccaa ttattgcaga tatacatttc gattataagc tagcccttga agctatagaa
     3061 caaggtgtgg atggaataag aataaatcct ggtaatattg gaagtagaga gagagttaag
     3121 atggtagttg agaaatgtaa ggaaagaaat ttaaaaatta gaattggagt caatggaggt
     3181 tctttagaga aagaactttt aaaaaagcat ggctctgcaa ctgctgaagc attagttgaa
     3241 agtgcaatgg gacatattaa gattcttgaa gacttagatt ttcataatat agttatatct
     3301 ctaaaatcat ccgatattta taaaactgtt gatgcatatg aattaatatc aaaaaaagtt
     3361 gattatcctc ttcatattgg aattacagaa tctggaagtg ttcacaaagg aacaataaag
     3421 tcttctatag gggtaggagc acttcttctt aaaggaattg gagatactgt tagaatatct
     3481 ttaacaggcg accctgttga agaggttatt gttggtaaac agattttaag aagtttggga
     3541 cttttaaatg ataagattaa agttatatca tgccctacat gtggtagatg taatatagac
     3601 ttaattagtg ttgtaaatga ggttgaagaa aagattggta gtatggaaaa aaatatcact
     3661 gttgcaatta tgggctgtgc tgtaaatgga cctggtgaag ccagagaagc agatataggt
     3721 attgctgggg gtaaaggtga aggtctttta tttaaaaagg gtgaaatagt tagaatgatt
     3781 gatggtaaca aattagttga tgagttgcta gaagagattg aaaaattata gtatacaatt
     3841 catatatata ttaattgact agatttttaa atacttttgt aataagtttt tatttacagt
     3901 atttaattat ctagtcattt tttattttat aaacttcatt aaatgtaaga aacttatatt
     3961 ctaatttgac tatatatgta tgagttaaat catattgtaa atttataaaa ttaaaaaaag
     4021 atttaatata gtgaaaattt ccatcaatag tattgaaact tgatagtaac tatgatagga
     4081 tatagttact agaacagttg gtaaattatg ttaacataga ttttaatgtt ttggtaaatt
     4141 gttttattat aagttaatag aaaaagaggt gaagaactgt gagatataaa aaaatatcta
     4201 gcttacctat tttagttgtt gctttgctga ttactggaac gacaacaaca ttttctctta
     4261 gtacgaccaa ttcagaaaaa acaaatgtat acttagcaag tacggtaagt actgtcacaa
     4321 agaaagtatc cgatattcaa agtagtaaag gtcttgttta taatgagaat attccattat
     4381 ttataaataa tagcaaaata cagtatgatg atactccata tcattggcct agcaatgtta
     4441 taagcttaac aaatagcagt gaaaaggcaa ttatggatta tgagattaca tgcttagcat
     4501 atgataaaaa tggaaaacca cttgagctat attgggatgc tcaaaatgtg gcagcagatg
     4561 gcgaagtagg aagtgttgga tttagcccag ctggtgtaga ctatggtatt gttacaggca
     4621 tatctcctgt gtctccaaaa tcatattcac atacttatag aaaaatgcaa caatcaccac
     4681 cacaggatat aataagtatg tttgaaaaac aacaaggcaa ggcatgggta gaaaattggt
     4741 tgaaagaatg gaaacaaatg gagaaagaat atgcaaagca aaatgcaata gcaccaggta
     4801 agaatcaaaa tgatgccttt ctattgtttg ataaatggaa acaatcaact ggagagcatg
     4861 gtgtaaagta cattatatct tgtgtaaaac aagtaacatt taatgatggt agtatatgga
     4921 aaaattcagc atatgagaat tggttgaaaa gttttcaagg gaaggaagtt tcaaatagtg
     4981 tattagaaaa ttactataag taatgtttaa tgatagcaaa atgagtacga atttaattaa
     5041 tgttaattta attaaataag gactattttg tttaaaaata tcagtgttac aaggaaattt
     5101 ttattgtgac aaaatggtat atattcaaaa taaaaaagca tgtgtcaagt tttgatacat
     5161 gcttttttat tttgaatata tgttttctat aaatttatga ttttttagtt atgtaatttt
     5221 atatgtgaat ttttagattt ttatatagat agtgaaataa tgtggaagtt ttatgtttta
     5281 aaaattttag ttaaaacatt tattaaaaaa gataatagaa atgttttaac taaaatagtt
     5341 agaattgaaa tgttatacag atagtataag tactatcaaa ttatataaga ttgcttgaag
     5401 ttaaataatt tatttaaata gaaaacagct gatttaatat cagctgtata tgaataaaat
     5461 tttgaattgt agtgtttagt tatatggata taattcataa taagttagca ataaatcaac
     5521 cattttacca taactctgag taccttcagt aacgccatta gcttttaagt aagaattgtt
     5581 aaactcatta gaaatttcat taattttacc ttcatatttt tgccaaaatt cactttcatt
     5641 ttttaaatct ctacggacag aatctgaaat gccagcagaa atatcaacat atgcattata
     5701 atcaacctta cttaaagcag aagcagtata atttaaagct aaaatatatc cagaatagtt
     5761 aaaatcaata tgggggtgtt ttatagaagt aagatacgct ataaaattag cctcatcttc
     5821 actagcaaat cccctttgat gtgctatttc atgttcaact gtacaaggaa tatataagtc
     5881 aggtattgct atatttacat ttgcctcacc tgtaaaagga aagtatatac cagttattcc
     5941 tgtatagcac attagatttg atgaaataat atacttaggc ttagaataac taccactaac
     6001 actaggtaat atatccaaga tattatcgta tcctagttga gctctattta tgacaccatt
     6061 ataatctgta ttagatttta caataccatt tttatcttgt aatgtgagtt ttctagtttc
     6121 atttgcttta attacaagga atttatataa tttagtaagc tctttaacac tatattgttt
     6181 tgattggata gaggtattgt tttttaaatt atagttattt ataagtgtgg tttctagtgg
     6241 aatcctatta tagtttattc cccaaagcac tacaaaaaga aagtagacta ttgatacaat
     6301 ggataatata tttaaaatgg aattttttaa aaatatgttt aatttttttt cttattaaaa
     6361 attgtagata aagtacaaca taaaaataag aagatagata taactattat gtacattgta
     6421 atctcataga gagaaaatgg gaaaattcca gaaactttac tcaatatttg tacaattatt
     6481 ttatctatga attgggagta atatttttca acaatatttg gaactttgct ggctataaaa
     6541 tttaaaagta aagcaatagg aaagagaatt aaagaaaaat attttgtttt tttgctcata
     6601 tttcacctca catacattag tttatataaa catattatat atcaattgaa gaaagattgt
     6661 aaaataagta taaatatatc tatttataac tttatactaa ataaatgata agttataata
     6721 tattaatatg aataagcagt atatatacaa ctaataataa gaaaaatatc aattatataa
     6781 ggagtagata aaaatatgat aataaaactt actaaagaca attttaattt tagatttaaa
     6841 caatatgaag gtatgttttt tcatgctgaa gtagttgaag gtatggaatc cattagatat
     6901 aaaataacta aggataaaga aggtacagaa ttaaaagaat ttggaagtac acatataaaa
     6961 gataatatga tatatgtacc tcaggtagaa gcatacatag atttgaacag tataaaataa
     7021 agatgtaaaa ttttaattaa aaataaagat tatgtttgag ggggaatcca atatgagtaa
     7081 gcctatagat ataacaataa gacctataag aagagaagat gcacaagctt ttaatgaaat
     7141 tagaagaaca tacagtgtta tgagaaatac tttggcatta atgagtgaca gagtcgataa
     7201 aactgaagct atgttagctt ctttgggaga aaatgattat atgtttgtag ctgaaactaa
     7261 taataatgga gaaaaagatg taataggttt tgctgggtta catgtaaatt cttctccacg
     7321 attgagacat agtgcagaaa taggaataag tgttgcagag aattatcagg gaagaggagt
     7381 aggtaagaag cttatggaac aacttttaga tatagcagat aattggatta tgttaactag
     7441 agtaggatta gaagtaattg tagataatga aaagggatta aatttatata aaaaactagg
     7501 ttttgaaata gagggaacta aaaaatatgc tgtaatcaga gatggaaaat ttgaagatgt
     7561 ttatattatg ggaagatata ataaaaattt aatttaaaga agctaataga gaagtaaaat
     7621 agagtgtctt taataaaaaa tttacattaa aaataatcta ttttacttct ctattgtatt
     7681 aaaaaactta tttttaaatg tttacaaaaa cattctatat acaaataaaa ttattagcaa
     7741 tatcaacgct attttaaaag ctaaactagc aacagtttta atgattttta cagaaacacc
     7801 tatagcaact atagcaaata ctattttaaa gagtaaatcc atatccatat ttaagcctcc
     7861 tattctataa tacatataga tattattgac aaatatctag gaaaaaattc catcaatata
     7921 ctacaataaa atgtttatat ttgtaattta ttgaatatgt tattatataa tacataaaaa
     7981 aataaatcaa gataagagta aaatacttat aaaaggtata gatataactg aaaatagtgt
     8041 tgtaaaaaac acacattgtg aagctagtgt tatattggag tcatattgat tagccattat
     8101 agcagtattt gcagcagcag gcattgaaga aattactact ggtatagcta aaatcatctt
     8161 atcatttatc catcctttta gaataaaata cacaatcaca ggaagtacca ataatcttat
     8221 aaaagtgact atatataatt ttttgttgac aaaacaatcg agagctgaag aattagcaag
     8281 taagcttcca atgataatca tggatattgg tgtagttata cttcccaaca tctcaagtgg
     8341 ctcgtttata aattggggta acctaagtcc tgttacaaat aaaaaaagtc caataacaat
     8401 agctattgta gcagggctta taagtgattt tattgaaaaa cctctacttg tactgccttt
     8461 agataaaaga taaattccta aagtgaaaga aaataagtta aaaggcaaat tgaatattgc
     8521 agtatagaat attgcttcat gacctaaaac tgcttcaatt acaggataac ccataaaagc
     8581 aacatttgaa aaaacaacta tatactgata tattcccaaa tcttttttat cattacattt
     8641 taaaatgtat ttcaataaaa atgcaattat aattgaaact atatacataa tcaaagatgt
     8701 aaataataac aatagtattt tttgtatcat tttactatca aagttaattt gcatggagct
     8761 aattatcatt gatggtaaaa aaactgtcat tgtcaaagtt gaaagcttag atgtgcagtg
     8821 gtcatctaat aagttgaatt ttctgacaaa atatccaact aaaataatta taaataaaac
     8881 tgcaacttgg ataaaaatat tgctgaaatt cataaaatgt ccccccctat atatacatta
     8941 tataccaatt acataataaa atctaatgat tataaaattt aaaatttaat gttacaatat
     9001 agtgacaaaa ggtaaaaatt caatattata gcattaatta tagattataa tgtataataa
     9061 tgtttgagag aatatatttt ataaaatggg taggtagcga ataatgaaaa atacaaaatt
     9121 ttctataaaa aaaataaaaa atatatctaa tgacccgaaa gtcgtacata ctaagggtgc
     9181 cctccttgaa aagatgggta agatggaaag cgcaatagag ttgtataaga gtgctgcatt
     9241 ggataattac gtaaaatctc aatatacttt aggaaatata tatgaaagta aaaaacaatt
     9301 taaagaagca gaaaagtggt attcaatggc atataaaagt ggaagtgaag atgctgcttt
     9361 tgatttaggt aatatgtact ataagttaga tggctatgaa tatgctatat attggtatga
     9421 aaagatagca aatttaggtt atttacaagc acaaaataat ttaggtgtat gccattttaa
     9481 aatgaaagat tttgtaaggt gtgaaaaatg gttaaaaaca gcagcagaca agaatttagg
     9541 taaagcttgt tttaatttag gggtattata tacttttttg gagaaagatg atgaagcata
     9601 tgaatactat aaaaaaggtt ctgtgctttt agatgatgat gcaaaatata atttagcaat
     9661 attaaatgga aaaaagaaag ataataaatc aacagtaagt ttatataaac agttgtacaa
     9721 gtcaggtcat atgaaaggtt gctttaactt gggtatgatt atggaaataa atgataattt
     9781 agaagatgca gagaagtatt ataaaaagag tgctgataga gatgatgtga agtctgagta
     9841 taggcttgca tatgtatatg atagaaaaga agagctggga gatgcaattt attattatga
     9901 gaaagcaata gaaaaaaatc atacactttc taagtataga cttgctaatt tatataatag
     9961 agaaaatgag atagagaagg caaaaactta ttataaaatg gctgctgaag atgatataac
    10021 agaagcaaaa aataatctgg caggtatata ttttgaagaa aaagattatg aaaatgctat
    10081 taaatattat gaggatgcta tagctgttgg atgcaaaagt tcccttgaaa atcttgggga
    10141 tttatattat cagaatcaag atatagaaaa agcgatttcg tattattcga ggattccaaa
    10201 taatgcatct tgtcaaatca aattaggaaa tatctatgaa gatttaaata atattgaaga
    10261 agccataagt tggtataaga aagcatctga aaatggagat acgaggtcta gttatagatt
    10321 ggggtgtata tatgagagct taggaaatac aaaaaatgct agaaagtatt ttgaaatggc
    10381 aagtagcaaa aatcatatga atgctcgtat acatctaggt agaatttatt ttagagaagg
    10441 taaattggaa gagtctaaaa tgatgtttga tacacctgcc aatgaaaata atgtgtacgc
    10501 tcaacatatg gtaggattaa tttatgatat gttctataaa gattatgtaa attctaaatt
    10561 ttggtatgaa aaggctagag cacaaggttg tgttgaatca atatataatt taggccaaat
    10621 ttatttaaaa ttaaatgatg acgcagaagc tgagaaatat tataaagaag gtattaaata
    10681 tggaagtaag aagtgtgagt atatgcttgc aggtctttat tataaaaaga gcctagatat
    10741 gtacatttct ttagcaaatg aagagtacga taattgtgaa gagatagtag aaggctttcc
    10801 caatttaaat atagactttg atgaagtatt aattcctcca tttaagttgc aagaagaggt
    10861 aatagatgaa gaagagtatg taccaattta tatactaaat ataaaagaaa gtttagattc
    10921 aatgctagaa gggcttgaaa ctgaaatgat tatagatgaa gaacatgata gttaaaaagt
    10981 attataagat tatatagatt taaatatata aaagccatta ggataaatgt aaatcaatta
    11041 attctaatgg cttttttatt aatattttat aatagcttat ttcttgacat gaaaaatgta
    11101 atcactatac atattataga ggtaataaga agtattatcc aaaatccgtt tgggttatta
    11161 gaaaatggca tgttgatgac attcatacca aagaatcctg atattattgt aggtattgag
    11221 aaaattagtg taactactgt taaaatttgc ataacattat tctgattatt acttataatt
    11281 gcactgaaag catccataat tctactcaat atatctccat atattttagc catatcaaga
    11341 gcctgtctat tttcaactat aacatcttct aataggtctt catcatctgg atacttcttt
    11401 ataccagcag ttctaaccat tttgtttaaa acaagttcat tagattttag tgaggtagag
    11461 aagtatacca aagatttttc taattccaat aattgaacca attctttgtt tttcattgat
    11521 ttgtaaattt ctcgctctat tatgattgtc attttattta tttttcttaa gtaatgcaag
    11581 taataagctg catttttgtg aagaatttga agcaaaaagc gagtcttttt aaacgtaaaa
    11641 aaatctttaa tatgaccaac tataaagtca tttaaaatct tagtctgtgc atcacaaact
    11701 gttacaatag cttcttcagt tagtataata cctaagggta ttgtagtata atgagaagaa
    11761 ttagagtcac tttcgtctac tggtatatct ataagtataa gagtatgatt gtcttcaaca
    11821 tctattcttg agcgttcttc ttcatctagt gcagattcta tgctttctac atctatattt
    11881 aataaattag aaatttcgtt gatttcacta tgattaggtt caacaagatt tatccaacag
    11941 ccatcttcaa aaaaactaag tttctctaat tttgaatcta tagttttgta atatcttatc
    12001 atggcaacac atcctttatt cagttttata taaatctcat catttaatag tatctattaa
    12061 ttaactaatt tatataactg aatatatgta ttagttttga ttttagatat tattaagtga
    12121 tgaaaatgta aaaaattctc tccgcaacgg actagtatcc attgcccatc actctcctta
    12181 tttattattt tatatatagc tatttatgaa atgcgtattt taagcactct ttaatataat
    12241 accttttcca ggtatataaa tcaagttttg atttgattaa ataatatttt taccataatt
    12301 tacacataaa gtatataagt tatatttaat ttgagtaaag aatatatata ttctgagtga
    12361 aattattaaa tatattaaaa aataagagtg tatatatata tttacttatt tgcaataata
    12421 tatttaaaaa agtattttat tttcaaaact agacttcatt tataatttat cacgaaaata
    12481 aaaggaatat aaatataaga gaatgagagg ttattagaga tatgagtgat tttaaagaaa
    12541 ttttggcaga agagattaaa aataatccat ttggattgat aggtaaagat tggacactta
    12601 taacagcaga aaatgaaggt aaagtgaata caatgactgc tagctgggga ggacttggag
    12661 ttatgtgggg aaaagatgtt gcttttgtag taataagacc acagcgttat actaaggaat
    12721 ttatagataa tacagataaa ttttctctta cattttttga tgaagatttt cgtaaagagc
    12781 tttcatattg tggaaaggta tctggtagag aagaggataa gatatcacag attggattta
    12841 atatagaaca cttaaatgat acaccttatt ttaaggaagc taaaatggct attatatgca
    12901 aaaaaattta tagtcagaaa cttgaacccc aatgttttat tgctgaaggt atagatggaa
    12961 gatggtatcc acaaaaagat tatcatactt tatatatagc tgaaataacc aatgtacttg
    13021 taaaagaaga ttagttataa gggttaatac tatctctaat taaattaaaa tttcaataaa
    13081 aggaaattga cacaaaaaag ctaaggacat aaatatgttt ataaagatta ataaataacg
    13141 tattaaaact ccttagcttg ataaaatttt aatttagttt tctttaaatt ataattcaga
    13201 aatcaattca ttgataacat cttcaacagt acttaattta tcaattttat aggcatcatt
    13261 tccacaaaat aaaagtgaat tttcaacatc tcctttaact gcattgatta gagcttgaga
    13321 aatacagtaa ggagtttctt ttggattaca aggaatcaaa caattatagc acttctttat
    13381 ttctggacga tttattttaa cttcttctat aaatttgttt cttatggcgc gtccaggaag
    13441 acctacagga cttttaacta tatgaacatc ttcttcacta gcatttatgt atgccatttt
    13501 aaagttctca tgggcatcac attcgtaagt agcaacaaat cttgtaccaa cttgtacacc
    13561 acttgcaccc atatctatat attttttaac atcactacta gaagttatac caccagcagc
    13621 aactactggt atgtttctac caaatttttc tccataagta tttgcaacct ttaaaatttc
    13681 aacaaattcc ttatcatagt ctatagaatc tatgttatca agttcctcgt tagagtatcc
    13741 aaggtgacca ccagcttttg gaccttcaac aactattaag tcagcagtag ttttctcttt
    13801 tctatcccac atttttaaaa ttacattagc agcttttgca gttgaaacta tgggtgctat
    13861 ttttacatta cttcccttta ctaatgatgg tagcttatta ggtaatccag ctccagatat
    13921 tataaggtct acaccagctt taacagcttc ctttacgtat gtttcatatt ctttcatagc
    13981 taccataaaa ttaataccaa taataccacc atttgagatt tctttggcct tagaaatatg
    14041 tttttttata gctcttaaat ttgcatttat agtattagtt tcaaaatctt cctcatcata
    14101 tccaatttga actccagaaa ttacaccaac accaccaagc ttagcaactg caccagctag
    14161 tgatgaccta gatataccaa cgcccattcc accttgaatt ataggaactt ttgcaactaa
    14221 atctctaatt attaactctt ttatgataat ccctcctcaa tgtaaacatg tttaaagaac
    14281 tagattataa tacttaatat tattacctag tcctaattat tatactacaa attataataa
    14341 aagagtagtt atattttgta tagaagacga taattatatt atatttaaaa cagctccatt
    14401 agaatcgcaa cataactctt ttatttccca atcagatttt agtttttgta ggtaattttt
    14461 catattatcc acaaaactat catcattttc ttttattaaa gacattatag taggtccagc
    14521 tccacttaaa aatactccaa tactatttaa ttgttcagat ttttcaacaa tatcattgta
    14581 gttctcaatt agagttcctc tataattttg atgcaatttg tcttgacaag ctactttaag
    14641 taggtcaaag tttttgttta gtaaggcaga tattagtaaa gcaactctac taacattgaa
    14701 taccccatca gaatatggta tttcctttgg taaaacacct ctagcttttt ctgttgataa
    14761 cttaaaatta ggtatcattg cacaaaattt aagttcttca ggaattttta taatatcata
    14821 atgtatattc tcattatcag taacagatac gatcatattt cctaaaatag caggagcaac
    14881 attatctggg tgaccttcta tttctgaagc tatatttaat aattgatttt tatctaaatt
    14941 agcacctgat agagcatttg cagctataac tccagctact atacaagagg cactactgcc
    15001 aagacctcta catataggta cttcactgtg gatttttatt ttgataccag caggtatttt
    15061 ttctggttta actctatcaa aaaagtactt catagatgta taaactaagt tattttcgtt
    15121 tttgtaagca tcttcacaac cttctatttc aagaccactt tcaatttctt caacataaaa
    15181 tttattgtat atatttaacg caattccaag acaatcaaat cctggaccta tattagcact
    15241 tgttgcagga actataatct ctaacataat aatcacctat acctttaaga atttttttat
    15301 agctagtttt aattcatctt tttcataaat atctttatgt agtatttctg catttttaag
    15361 atttttaata ggttttggaa tatctatttt agaaatactt gataatctat caattatagc
    15421 aaagtcatca aggtctttaa aatcacaatc tatagacttt agaacatctt cagaaaactt
    15481 gaatggactt gcagtactta caataacagt ttttgtgtta tcagaagttt cttttttata
    15541 tttttcataa caattgtatg caacagcagt atgagtatct atcaaataat tataattttt
    15601 aaacacattg tttatcgtgc ttttaacttc ttcttcattt gaatattctc catagaatga
    15661 ggctaaattt ttttccatat catcacttat tttgtagact cctttatcac taaggtctga
    15721 taacagctta tttacaatat cagtatttct atttgatatt tcaaacagta atcgttctaa
    15781 attacttgaa attaatatat ccatagaagg agaagtagtt aatttcaatg ttctattttt
    15841 atcatataca ccagttttaa agaaatcata aagaacatta ttatcatttg atgcacatat
    15901 caatttgttt attggaagac ccatttgttt ggcataatat ccagctagaa tattaccaaa
    15961 attaccagtt gggacaacaa aatttatttt atcatttaaa tttatctcac tattgctaac
    16021 taatttcata tatgaataaa aatagtatgc aacttgtgga agaagtcttc ctatattaat
    16081 tgaatttgca gaagataata tataattatt atccaatagt ttttgattaa attttttatc
    16141 agaaaaaatc ttctttacac ctgattgtgc atcatcaaaa tttcctttta taccaactac
    16201 atatgtattt tttccagttt gagttttcat ttgaagtttt tgtactgggc ttacaccatc
    16261 ttctgggaag aatacaatta tctttatttt atctatatct ttaaatccct caagtgcagc
    16321 tttgcctgta tctccagatg tagcagtaag aatcacaaca tctttctcta aattatcttt
    16381 ctttatagat gttttaagaa gatgaggcat tatagtaagt gccatatctt taaatgctaa
    16441 agttggaccg tgatatagtt ctaagaaata agtatcattt actttattta atggagctat
    16501 actactacaa tcaaactttt catcatatgc attttctata caatttttaa tttcatcttc
    16561 agtaaaatca cataaaaatt tactaagtac aaaaaatgct atctgagaat acgttaaatt
    16621 tactaaattt ataagttcat tttttacatt gggaaattca cttggaacat aaagaccacc
    16681 atcacttgat attcctttta ttattgcttg tgatgcagtt actttttctt cggtgcctct
    16741 cgtacttgaa taatacattt tttataatcc tccatatatt ttaaattttt aattagctaa
    16801 ttaaattaga tacagaatat tttaaaaacc gaatttaggt aataaaaaaa gaccctcatc
    16861 cctaaaaaag ggacgagaat ctgtttcccg cggttccacc caaattgatt ttaaaaaatc
    16921 cacttgatac tttaacgcaa gtaataaaaa cgtctattcc tactaaaatc attaagataa
    16981 cttcggatag aagctcctag gtagttttca atccttctaa ttagggaaac atttcagcta
    17041 gtagtttcct tctctggtaa tcgattcaga tttactcttc ctaatcaatg cctttcaata
    17101 ttcttaatat tattaattat tctagtttat aaaacagaca aagtcaagta ttaatataaa
    17161 aatttggaaa aaatattttt taaattgt
//
LOCUS       DAEQJM010000073        16756 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.074, whole genome shotgun sequence.
ACCESSION   DAEQJM010000073 DAEQJM010000000
VERSION     DAEQJM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16756
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.074"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(72..275)
                     /locus_tag="KRQ43_003045"
                     /pseudo
     CDS             complement(72..275)
                     /locus_tag="KRQ43_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
     gene            complement(275..604)
                     /locus_tag="KRQ43_003046"
     CDS             complement(275..604)
                     /locus_tag="KRQ43_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HBH2743388.1"
                     /translation="MPQIKIRGINENDICKISKKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            934..1860
                     /gene="fba"
                     /locus_tag="KRQ43_003047"
     CDS             934..1860
                     /gene="fba"
                     /locus_tag="KRQ43_003047"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HBH2743389.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(1995..3626)
                     /locus_tag="KRQ43_003048"
     CDS             complement(1995..3626)
                     /locus_tag="KRQ43_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2743390.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(4109..5146)
                     /locus_tag="KRQ43_003049"
     CDS             complement(4109..5146)
                     /locus_tag="KRQ43_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH2743391.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(5165..5950)
                     /locus_tag="KRQ43_003050"
     CDS             complement(5165..5950)
                     /locus_tag="KRQ43_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH2743392.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(5983..7116)
                     /locus_tag="KRQ43_003051"
     CDS             complement(5983..7116)
                     /locus_tag="KRQ43_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH2743393.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(7164..8291)
                     /gene="hadC"
                     /locus_tag="KRQ43_003052"
     CDS             complement(7164..8291)
                     /gene="hadC"
                     /locus_tag="KRQ43_003052"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HBH2743394.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKNETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(8291..9517)
                     /gene="hadB"
                     /locus_tag="KRQ43_003053"
     CDS             complement(8291..9517)
                     /gene="hadB"
                     /locus_tag="KRQ43_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HBH2743395.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(9532..10332)
                     /gene="hadI"
                     /locus_tag="KRQ43_003054"
     CDS             complement(9532..10332)
                     /gene="hadI"
                     /locus_tag="KRQ43_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HBH2743396.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(10371..11570)
                     /gene="hadA"
                     /locus_tag="KRQ43_003055"
     CDS             complement(10371..11570)
                     /gene="hadA"
                     /locus_tag="KRQ43_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HBH2743397.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            12247..13245
                     /locus_tag="KRQ43_003056"
     CDS             12247..13245
                     /locus_tag="KRQ43_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBH2743398.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            13607..14134
                     /locus_tag="KRQ43_003057"
     CDS             13607..14134
                     /locus_tag="KRQ43_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HBH2743399.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            14161..14757
                     /locus_tag="KRQ43_003058"
     CDS             14161..14757
                     /locus_tag="KRQ43_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HBH2743400.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKDVIDTVSISLNAPNKEAYNRVTQPKFGEKSFDYMLGFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(14822..16405)
                     /gene="asnB"
                     /locus_tag="KRQ43_003059"
     CDS             complement(14822..16405)
                     /gene="asnB"
                     /locus_tag="KRQ43_003059"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH2743401.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
BASE COUNT         5191 a         2976 c         2113 g         6476 t
ORIGIN      
        1 gtttccctat atgctgacta ttttagctac taactcatga ctaaagtcac gagtgtacgt
       61 agctattttt taatcaaata tatatattct ctatatataa cttcttctcc attaaataat
      121 atctcatcat tttcagtgtc tacttgagtt cctggatttg aaacttcact tccatttact
      181 actacagacc cttgtttaca atacttcttt atttcacttc tacttccata acctaaattt
      241 gaaagaattt tatctatacg ttgcttttta gccattaaaa atgctctcca ttctcataat
      301 atttttcttt ttcaaatact gtaaatgcta aatccatact ttctacatct aaattatttc
      361 ttatactatc agttattatt cttgctacta tatcttgtac ttcttgtcct ctatcaaacc
      421 aagctacttc aacaaaagga tatacatctg ctattttacc atctcttatt gcaactgact
      481 ttatacattc tatttcaaag tagtctcttg gacattttac agcttcaact aaatcattta
      541 tcattttttt acttatttta catatatcat tttcattaat tcctcttatt tttatctgtg
      601 gcatagttta tctcctttat tttaaatttt tagtgaatta tcatccactt aattcccttc
      661 gataacgttt gaagtggtaa cttcttggtc aagacaacta ttgttatcag tatctccaaa
      721 ctaataaggt agttcctacc cttatagtta gcattatata gctaattttc ctaaattatt
      781 tatattcttt attattttat ttaatcctat tgtcttctat ttaacattat acttgtaatt
      841 tatagttatt acaatttact atatactttt tttgatttaa cgttataata taagtgatgg
      901 gtaaatttta aaagttaata ggaggagttt aaaatggcat taattactac aaaagaaatg
      961 tttaaaaaag cttacgaagg tggatttgct ataggtgcat ttaacataag tgacttagaa
     1021 caattacaag gtgttttaaa agctgctaaa gctaaaaatt cttatgttat gatacaagct
     1081 tctatgtcag ctgttaaata tgctggacct catacattag ttgaaatggt taaggctgct
     1141 tctgatgaaa taggtgtaga tgtagctctt cacttagacc atggtccaaa tatggatgct
     1201 attaaaactt gtattgatgc tggtttctct tcagttatga tagatggttc tcattttgac
     1261 tttgaagaaa atgttagaat aactaaagaa gctgttgaat atgcacactc taaaggtgtt
     1321 gttgttgaag cagaacttgg tgttctagct ggaacagaag atgatgttac ttctgatgtt
     1381 cacaagtata ctcaaccagc tgaggcagtt gagttcgttg aaagaacagg tgttgattca
     1441 ttagcaatag ctattggaac ttctcatggt gctttcaaat tcaaaggaga agctaaatta
     1501 agatttgata tactagaaga aatccaaagc aaattaccag gtttcccaat agttcttcat
     1561 ggtgcatctg ctgttgacca aaacgctgtt gctacatgta atgaatttgg tggaaatata
     1621 gctggtgcta aaggtgtacc tgtagatatg ttaagaaaag catcttctat ggctgtttgt
     1681 aaaataaaca tggatactga cttaagacta gctatgactg ctgctatcag aaaattctta
     1741 gctgaaaatc caaaagaatt tgacccaaga aaatacattg gtgctggtag agatgctata
     1801 caagctgtag ttgaaagcaa gatagatgat gttttaggtt ctgctaactc tataaactaa
     1861 tataactttt aaatatttat aaaagaaaag agatgactta aagtaattaa atttattttt
     1921 aagccatctc ttttaagttg tatcaattat gtatcttata atattttaat tatattgtct
     1981 ttttaaactg acagctaaac gtgaatatgt ccactcttta tctttctatg gatggtagaa
     2041 ggatatatac ctataacttc agcagccttt gttattgaac catacttatt tatagcctta
     2101 cttatcatta tttggtccac tattttatat gcatcattaa gattcataat tccatttacc
     2161 actattggtg ataaatcatc tgtttcatta tcaatcatat ctaaatttat cagcatgtta
     2221 aattcatctt ctccaattac atttttagct gataatacta caaatctttc aatgatgttt
     2281 tttaattctc ttatgtttcc tggccaagaa tattcttcta ataactcaat aactttaggt
     2341 gaaacttcta cttctctatt gtacttttca ttgtaaagtt ttaagaaata atttactaat
     2401 ggtactatat cctcttttct ttctctaaga ggaggtattt ttactggaat aacacttaat
     2461 ctatagtaca aatcttgtct aaatttaagg ttatttctaa ggtcttcatg agaaatatta
     2521 gtagcactta tatatctaac atctattttt ataggcttac taccacctat tctagtaata
     2581 gtattttctt gtataaccct aagtaatttt ttttgcatct gcattggtaa ctcacctatc
     2641 tcatccaaga aaatagttcc accattcgcc tcttcaaaaa gtcccttttt accttttttc
     2701 ttagctccag taaaagaacc ttcttcatat ccaaaaaact ctgactctaa taattcattt
     2761 ggtatagctc cacagtttat agctataaaa ggtttgtctc tccttgaact atacttatat
     2821 attgttcttg ctattatttc ttttcctaca cctgattctc catttataaa tatagaagaa
     2881 tctgaggctg cagctctctt aacaactttt tttatattgt ccataatctt actttgactt
     2941 atatactctg tgtcttctga tatatcacta tattttatct gagattcaag cttaataacc
     3001 cttgaaatat ctctccctgt tagtactcct cctgtaagct ttcccttaga atcccatctt
     3061 ggaactgccg tatatgcaat aagcttccca tctgggtaaa cgatatttct ataaatcttt
     3121 ttcttcactt taagcatgtt taatattatt ggttcttcaa ctaatccttg tctcacaagg
     3181 tctgttatat ttctaccaag tacctcagtt cttttaaaag gtaatatctc atcactgaca
     3241 gtgttcatct tttcaattac cccatctttg ttaaacacaa caacaacttc atctatatgc
     3301 tctattatat cttcaattac tttatcagat attagagact tctcaaataa ataaactata
     3361 ttattttcat tattattatc tttcatattg tatatatgtg cagtcatcct taactctctg
     3421 aaagctattt tctttttact atctgtcagt atttctgttt tgtcaaaatt tgaatctaat
     3481 tcatttatat ttctaggctt ttttatatct agaaaactaa aaatactatc tattagatga
     3541 ttacagtata ttatttcgcc tgattcttta cataaaatgg ctggattttc tacatgttct
     3601 ataagcccta ttaaattatt atccattaat attcgcacct ttcattaagt aatttattga
     3661 actacataca aaatttattg tttgcttaca ataaatacca tcagcacata taatcaactc
     3721 cttataatat tcgtcttttc aagtagttta tttcattaaa acgtaactaa gatataattt
     3781 taatgattat agtttgttaa aaatttcatt ttgcttttaa ttgtatttta tcacatattt
     3841 agtaattatt tgtctattta atacaattta attaaattta agatttattt aaaaaaacaa
     3901 agataatcct tacagaatat aactcacaat ttgtaagcaa tatacatata aggattatcc
     3961 agattatctt gtattataaa attttattca aacagacttt ttaataactg acaaatacac
     4021 actagcaata acttatcaaa gggttaataa ttatgttact aactaataag acttattcaa
     4081 tcagtaatat ttatatagtt tgtatctatt aagcttttat agcttctaat aaatcatcaa
     4141 cgctatctaa tttttctata agcattggaa ctatttcatg taagtctcca actactccat
     4201 agtcagcgat ttctaaaatt ggagctgctg ggtttttgtt tatagcaatt atgaaatctg
     4261 atgattgcat acctgctaaa tgttgtattg ctcctgatat accacaagct atatataggt
     4321 ttggtttaac agtagttcct gtttgaccta cttggtgaga atggtctatc catccagcat
     4381 caacagccgc acgagaagaa ccaactactc cacctaattt gtcagctaat ttcttaagca
     4441 tttcaaatcc ttctggtcca cctaatccta aaccacctga tactataaca tttgcatctg
     4501 taagagatac taaatctttc ttagttttaa ctgtttctaa aacagtagtt cttatatcat
     4561 cttgagttat tttgtagtct aatgctataa cttcaccagt tcttgtttcg tctttttcag
     4621 ctttatccat aacaccaggt ctaactgtag acatttgagg tctatggttt ggacaaatga
     4681 ttgtagccat tatgtttcca ccaaatgctg gacgagtttg ttttattttc ttatcttctg
     4741 ggtctatttc taacttagta cagtcagctg ttaatccagt tccaactctt gaagctattc
     4801 taggtgctaa gtctctacct atatgagttg ctccgaaaag cattatttct ggttttattt
     4861 catctattgc atcttttatt acttttgtat atgcatcagt tgtatatttt tctaaaagag
     4921 catcatctgc aacataaact ttgtcagctc caaaagtgat taattcttta gctaatccat
     4981 caacatcttt tcctaataat attgcacaaa gttctgcatc tacttcttta gctaattttc
     5041 ttccttctcc taataattct ataactactg gagctatttt tccttctctt tgttctgcaa
     5101 atatccatac gtttttataa gaacttaaat cttttatatc attcatagtt tgtactcctc
     5161 caacttatat aatgtgcttt tgttttagac cgattattat tttactagct atttcatcag
     5221 ctttaccttc taagatttct ccttttcctc ttggttcagg agtaaatgat ctaaatactt
     5281 tagttggtga tgcttttaaa ccaacttctt ctttatttac atctaaatca tcaattgtcc
     5341 aaacttttac atcatgttta tatgctttta ctattttatc aacagacatg tatctaggtg
     5401 tatttaactc ttttactgct gttaaaagta caggtgtact tacttttatt aattcgtatc
     5461 catcttctaa ttgtctttga actattatat cttttccttc tattttgaaa tcttgtacat
     5521 atgtaacttg aggaatgtct aatttctctg caatttgtgg tccaacttgt gcagtatctc
     5581 catctattgc ttgtcttcct gcaaatatta tgtcatagtc acctacttta gatattcccg
     5641 ctgcaatagt atttgatgta gcccaagtat cagctcctcc aaatgctcta tcacttaata
     5701 atattgcatc atcagcaccc atagctaaac actctcttag cataaagtct gcttgaggag
     5761 gtcccattgt tataactgtt atagttacat catcatgctc atctttaatt tttaaagctt
     5821 cctctaatgc atttgcatca tctgggttta atatacttgg aactccatct cttataagag
     5881 tacctgtttc tttatttatt cttacttcgt tagtatctgg aacttgtttt acgcaaacta
     5941 atattttcaa agtctatacc tccaatttca ttagattatt tattatttta atacgtttga
     6001 tgaaattacc attttttgaa cttctgatgt tccttcgtat attgatacga ttctagcatc
     6061 tctgtacatt ctttcgattt cataatcttt tataaatcca tatccaccgt gaagttgtaa
     6121 tgctttataa gcaacttcat ttgcaatttc tgatgcatag tatttagcca tagcagattc
     6181 ttgagcaact ctcattcctg catctctctt ttgtgctgca tcataaacta atcctctagc
     6241 tgcacaaact tttgtttcca tgtcagctat agtaaattga gtattttgga atttagctat
     6301 aggcttacca aattgaactc tttgttttgt atatttaaca gcttcatcta aagcaccttg
     6361 agctattcct agagctaagg cagcaacacc tattctacca acttctagag tacccattgc
     6421 tatcttaaat ccttgacctt cttttccaag taagttttct tttggaactt taacgttttc
     6481 aaatattaag tcagaagttt cagttcctct tatacccatc ttatcttcat gagctcctgt
     6541 tgagaaacca tcccatttac tttctactat aaacgctgat gttcctctaa gtcctttact
     6601 tctatctgta actgctatta ctatagctac atcacagaat ggtccattag ttatgaaagt
     6661 ttttctacca tttaatatat agtggtctcc aactaattct gctgttgttt gttgtccacc
     6721 tgcatcagaa ccagctcctg gctcagttaa cccaaatgct cctattaatt cacctgttgc
     6781 tatacctttt aagtattttt gtttttgctc ttcagtacca ttgtaaagta ttggtaatga
     6841 agcaagagaa gaaccagctg taacaaaagt agctgttgaa gcacatcttc tagctatttc
     6901 ttccattact atagcgtaag aaacatatcc tgctccccca ccaccatatt cttctgggat
     6961 attactgctt ataaattttg catcagctaa ttttttgatt aattccttag gcattacacc
     7021 tgttttatcc atttctgctg gtaaagtatc taattcttta ctaacaaaat ctcttactgc
     7081 ttttcttaaa agttcttgtt ctttgttata taacatagct tcctccaatt ttcatatttt
     7141 atagtaaatt tattttaatg aacttacgct aaactcatca tctcagcaaa agtttgaata
     7201 cgagttctgg cttgttcatt attctgagtt tgttggtcga tttcaacata taaagtaggt
     7261 attccactat cttctatatc ttttctaact aaaggataat cgtattcttc tgggtcacag
     7321 aatttcatca tacagaagat aacaccatct atatctttct ttttaacttc atctactata
     7381 agtgacccac gttttttctt agggtcataa gctaatgaac atccttctat gtttgaccat
     7441 tgtcttgcta atctctctaa cgcatcatca cctgctggta catctgttct gaattgtctt
     7501 gtttcttgtg ctaagtcgtc agctacaact gatatattgt tgtcttctaa aatgtctaat
     7561 atatctttag aatcagctaa tatacctgtt aataaaactt tttttccaga acagacttct
     7621 tctggcatag catttaattt tgctattaaa tctttcacta gctcagtatg ttcttctttt
     7681 ctcataaaga acccactttt aattactaag cttcttattg atggttttat agtattagaa
     7741 tgtttataag ctacttcaac aaagtctctc atagtttttc tatgttcatt gtaaacttct
     7801 atactttcat gaatttttgc ttcttctatt tcatatccac aaatttcttc aagttctctt
     7861 tttacacctt tgtactcact gattaagtat tttacaccag cttcaagttt tctattttgt
     7921 gggtgtacta atgatatata ttttatatga ggtactgctg atttccagtt ttgtcctaaa
     7981 caaattagtg tatcacacat acctggtata ataactccag ataattcatc ataagcacct
     8041 tttaatccat attctaaaca tgattgcatt attgaacatg caaatgcagg gaaatattgt
     8101 ttagctaaat ctaattctgt ttgtcctccc catataccaa ctggaagcat tccagctgca
     8161 tgtataattt cttctgggca ataaactggg aaacaaccta tagctttttt accagtttca
     8221 tttttatatt tttttacagc cgcatttgga ttttcaacta cttctttcat tttagataaa
     8281 atagcttcca ttatatctca cctctattaa gtttttttct ttcttccatt acttcaacta
     8341 aaccttgaat tcttgtttca aattgagcat tagtgaaagc tctagggtct gcttggtcac
     8401 catcaaatcc agcatatggt aatccagttt cttcagctgc tcttctttgc atttcatatt
     8461 gtattaaact cataagttta cagcttctgt tcatatgata gaatgctcca tcacatttac
     8521 cctctactaa agaatcaact ctatattttg tcatacggtc taggtttaca ttgttaaaca
     8581 tagtactata tgctactgcc attccatcta aatcattaac ttcatattgt aatgcccaag
     8641 catgtgggta aacactacct gtcatgttaa ctccaaattt agctaatgtt ttcatcttgt
     8701 atcctatata tggccaacaa ggtatacctt ccatcattat tctgtatttt tcttcccctc
     8761 tgaaagaaga tttaccagtt ttcatgttgt cttctaattc ttctataagt aacttaaatg
     8821 cttctgtagt ttctttttta cctctagcac aaactattac agccatgtaa gtaaataagt
     8881 caaatccatt cattggagaa ggagaagaat ctgctggtaa actcatagaa tacttccata
     8941 gtcttccgtt ttcagctgat attttcatta cttcttcaaa cttcttaggg tcaaatttct
     9001 ttcctgatat aatttctagt tgttttatag cttcttcaaa ttgagcttta atataatcta
     9061 ttcttgattg agtaacttcg tcttcattat tgaaagttgt atcaatcatt attaaaggta
     9121 tatctaattc tcttgaaata ttttcatacc attttataac ttgattacat atattgttac
     9181 agcaaagtag gaaatctgga gctggcatat ccaaagcttc acatccacca ttttctaaaa
     9241 gaccaaaatt tgttcttgca tatgcacata ggtcaataga atatccttta gattcagcta
     9301 tttcacataa ttctaaagaa ccttttttag ctgctactcc agctgcttgg ttttctggat
     9361 ataatacgtt taagtcaaat acttctgcta actcttgagg aaatactgat gttgaccaac
     9421 ctacaggtct tccttcttct ttagctttaa atgcatttgc atattgttca gctaataaat
     9481 cattaattac tactctagct tctttttttt cagacatttt catccctctt tttatatatt
     9541 tttcacttct ttttgtgatt cttttgcttc atcaaaagca tataacgctg ctcctaaagc
     9601 accagttaat tgaggtatat caggtacaat aatttctgtg ttgatttctc ttgccatagc
     9661 tcttacaata ccactatttc tagcaactcc accaaccata actacatttc tttgtactcc
     9721 tattcttttt actaggctag aaactctctt tgctactgaa gtatgaatac ctgccactat
     9781 atcttcaatt tttgcatttt cagataaatg tgatataacc tcagactctg caaatactgt
     9841 acatgtactg cttattgata cttcattttg agaattcata gatatacttc cgagttcaga
     9901 tacatcaacc tctattattt ttgccattac atctaaaaat cttcctgtac ctgcagcaca
     9961 tttgtcattc ataagaaagt ttaatagtct tccattatta tctaatttta atacctttgc
    10021 atcttgacca cctatgtcaa taatggttct tgtctctgga attatgaaat ttacccctct
    10081 agcatgacag cttaattcac ttatttgctt atcagcatct gaatagttca ttcttccata
    10141 tcctgtaact acaacttttt taatatcttc tcttgcaaga cctgtcttgc catataattt
    10201 ttctaaaact cttgatggtc cagtagtccc agtaccagag gatattgttt cagaagctac
    10261 aatatcttcc ccattcttta agattactcc ctttgatgca gttgaaccta tatctaatcc
    10321 cattgtgtac atctttagca ttctcctttt aaaaaatcta gaattactaa ttaatatctt
    10381 acaactttac tatctttaaa gttatttatt ttctcttcat cgtagcctaa agattttaat
    10441 acttctacag tatgttgacc tacttttggt gctggtgtat attctttaat tccttcattt
    10501 ctaaacataa ctggagtatt aactaagaca cctgtatttc cgctatcgta tgttttctta
    10561 aataagaagt catttgccca agcttgttcg tcatctaata aatcttcaca gctttgaatt
    10621 ttttcaaatg gtaagtctgc ttcttctaat aaagctgacc actcgtctaa tgttttttct
    10681 aacatagctt ctccaactat cttaactaaa tcttcaacat gattaaccat tgaatctatg
    10741 ttattatatc tatcatcttc taatatatat tctctattta taaccttaca gaatttgcct
    10801 aaccacttgt tgtattgtat taaagctaat tgaatccatc ttccatcttt acatttatat
    10861 gtagtcatta atgggctgtt tggattttct cttgataaag gcatttcatt tccgtattgt
    10921 gctgttgtta tcattgttcc cattccatat atagctgtat ggaaaagact tactgttact
    10981 ctctcacctt taccagtttg agctttttta tgtaatgctg ctaaacttcc tgctgctagt
    11041 gctagacctg catagtggtc accaaatcct gctgctgtat ttgctggaga tgttcctttt
    11101 tccataacag attggctaac tcctcctctt gcgaagtatg cagtatagtc aaatcctggt
    11161 ttatctttta aaggtccttt ttcaccatat cctaatattt gagagaatat taatcctgga
    11221 tacttatctt ttatttggtc ataagctata cccatttttt ctaatgcttg aactctaaca
    11281 ttagttacaa atatgtctgc ttctgataat aatttatgta atatttctac tccttctttt
    11341 gattttacat taatacttac acccttttta tttccatttt ctaattcaaa catagggttt
    11401 tcatcatctg atgctggaga tttaaatgtt ccacccataa ctcttattcc atcaccttct
    11461 ataggttcaa tcttaataac ctctgcaccc cagtcaccta acatttttgc acaacatggt
    11521 gctgcgatga aacttgaaag ttctactact ttaactcctt ctaaaagcat aacgttttcc
    11581 tccttaatag tatcaattat aaaatttcga ttaaatcact cataaaatac ttttttctga
    11641 tattaactgt ctgatgtcaa agttcctaat cttatctaaa ataacttaaa aattattaaa
    11701 attatttttt attgttttat tgtcttacac ctatattgtt aagcatttat cgtgccaact
    11761 ttatatttaa tcaaaatatc gcttgatttg aatgtttttt aacaatatgc aattgaataa
    11821 tctttttcat atcgtggcat cttgccacta tccattgcat tttgctattc tttctatgct
    11881 tataaaagtt ttttttatat atttttttat gaaaaagctt gacatttcaa aaaaagtttt
    11941 cattgctaaa ctcaaaaaca catgttatca ttgtaattaa tcagcaagtt agttaactaa
    12001 tttcaaactt agataatttt ttaataatat ttaatctaaa aaataacaat ttctttgata
    12061 aattttagag taattattac attaaataaa aaattactaa atatcaaaat aacacaggga
    12121 aaacaatttc aaaactaaat ttttaacctt aaaaattttg tataaaaaat ataaccttat
    12181 atgctacata ttatttctaa atgaaaaatt accataataa tttaataatt acaggagggt
    12241 attgatatga aaatactagt atttggagca cgcgattatg aagaaccagt aataaaaaaa
    12301 tggtctgaag aacataagga tgttcaagtg gatatttatc ctgaaaacat gactgaagaa
    12361 aatgtagtta aagctaaagg gtatgatggt atatctatac aacaaactaa ctatatagat
    12421 aatccttata tttatgaaac tttaaaagat gctggggtta aagttatagc ttcaagaact
    12481 gcaggggttg acatgataca ttttgattta gttaatgaaa atggacttat cgttacaaac
    12541 gttccttctt attcacctaa tgcaatagct gaattagctg ttactcaagc tatgaacctt
    12601 ttaagaaaga ctcctctagt aaagaaaaaa gtctgtgaag gtgattaccg ttggatagct
    12661 gaacttcttg gaacagaagt tagatctatt acagttggtg ttataggtac aggaaaaata
    12721 ggtgctactt ctgcaaaatt attcaaaggc ctaggagcta atgtaattgc atttgaccaa
    12781 tatccaaata gtgatttaaa tgatatatta acttacaaag attctttaga agaccttcta
    12841 aaagaagctg accttataac attacatact cctttacttg aaggaacaaa acatatgata
    12901 aataaagata ctctagctat aatgaaggat ggagcttaca tagtaaatac tggccgtggt
    12961 ggtttaatta atacagggga tttaatagaa gcactagagt caggaaaaat tagagctgct
    13021 gcccttgata catttgaaac tgaaggattg ttcttaaaca aaaaaatgaa tcctggagaa
    13081 ttaactgacc cagaaataaa taaacttctt tctatggaac aagttatatt cactcatcac
    13141 cttggtttct tcactagtac agcgattgaa aatatagttt attctagttt aagtagtgct
    13201 gtagaagtta taaaaacagg aactgctact aatagagtaa attagtattt tataaatata
    13261 ttttttcatt aattagctat tatctaacaa aatagccttt aatttcccaa atataagaga
    13321 gtcagctcag tatatattga gtagactctc ttatattatt ttttatatta aacttgtact
    13381 cctcttattt ataccaaatt aaatttatat taacttactc taactactcc tactctatac
    13441 attttaccta tttttacttt tctaattata tacatttgaa tgggtacaat ctgtatttta
    13501 caaaaaaaac acctaacaaa ctatgaaaat tgtatgatta atattaatat atttataaga
    13561 aaacataaca attatgttag ctctggattt ttagggaggg agtatattgg aaaaaatgaa
    13621 taaagttact tctaaaaaaa ctacctatat tgttacttca gcattatttg catccataat
    13681 atgcctgaca atagcatata tattacatat tccagttggt ggaaacaatg gatatgttca
    13741 tataggagat gcttttattt atctagctgc aactattttg ccaacaaact atgctatagc
    13801 tgcttctgca attggtgctg gtctagctga tttatctaca ggtgctgcta tctgggtaat
    13861 accaactata atcataaaac caatacttgt attatttttc acttctaaaa gtgacaagat
    13921 aataaataag agaaatatag ttgcttcggt tgtagcaggt atagtaggat tagttttata
    13981 catgtttgct gaaggtataa ttattggaag ttttacaagt gcatttgtaa tgagcttact
    14041 tggcttatta cagccaatag gaagttttat tgtttttata atcttaggta tggcacttga
    14101 taaacttgat tttaaaaaac gttattttaa ttaagaattt aaatttatgg agggaaaatt
    14161 atgaatatct tatatacaat tgaaaatagt atctatgtaa atataactaa tacatgtcca
    14221 tgtagttgtg ttttttgtat aagaaacgaa aaagatgaag ttgcaaatag tggtagttta
    14281 tggttggagc atgagccaag tgtagatgaa gtaaaagaag ccttcaataa atacaattta
    14341 gacgactatg atgaaatcgt attttgtgga tatggcgaac cattaatgag aataaatgaa
    14401 ttgatagagg tagcaaagtt tataaaagaa aaaagtagca taaaaataag aataaataca
    14461 aatggtctaa gtgatttaat acataacaaa aaaacagcta ttctgttaaa agatgttata
    14521 gatacagtat caataagtct taatgcccca aataaagaag cttataatag agttactcaa
    14581 ccaaagtttg gagaaaaatc atttgactat atgttaggtt ttgcaagaga ttgcaaaaaa
    14641 tatataaaag aagtagcttt ttcagtagta gatgaaatat ctccagaaga aatagaagaa
    14701 tctaaacaac tggcaaaaaa acttgatata ccattaagag ttagacataa gaattagcaa
    14761 gtaaaattat aaaacattaa gaatcacctg aatggtcttt caggtgattc ttcctcttgt
    14821 attaacattt tacaaaatag atttcatacc acactaggaa tgtgtaaatc atccaaatct
    14881 ttctccaatt atcagagttt ccactaatgt agtcattaaa aatctcatta atctcatcta
    14941 tgttaaagaa tttatctgct atctcactat tgaatttatc tcggatatcc ttattatatt
    15001 ggtcatcagc catccatata cgaattggca caataaatcc taatttattt ctaaaagcaa
    15061 tctcttctgg taatgttttt gatgcagctg tacgaaaggc aattttattc tcttttcctt
    15121 tcactttata ttctgatggt attctggatg caatatcaaa tattcttgta tctgtaagag
    15181 gcattctgac ttccaatcca actgcagtac tcattttatc tatattaaaa taaatatctc
    15241 cttccaacca tatttgaata tctacatttg acatgttagt aagtgtatct agttcttctg
    15301 tttcttcata aattcctttt accacttcaa taggaagcac atcaggattg tatttcttaa
    15361 gaatttttct tttctcaccc tcattcataa tgtttgtatt tccaatataa aatgtcttca
    15421 aattctctcc ataacactct gccttatggt atatattata tccaccaaaa aactcatctg
    15481 ctccttctcc agagtaacag atatttgtgt tttcagctgc tgccttgcat ccaatagcaa
    15541 aaacgatagc agatgcatct ccagttggtt gctccatatg gtacattaca taaggtactg
    15601 acgcaaaata ctcttcaggt gtaattatat atctcgaatt tttacaccca agaatattag
    15661 ctgtctgttg tgctaatttt gattcatcaa aacgctcttc ctcataacca catgaacctg
    15721 ttttttctat atctgacatt gccaatatat aagatgaatc aacacctcct gataagaata
    15781 actctgcagt ttcattctct gattttacct ctggcataat tttctgaagt gttgtatgaa
    15841 tttcatccgt ccattcctca atagacttgc tgtggtcagg atgaaattca ggtttccaat
    15901 aacgaccaat acatactgtt ttattctgat agacaaggta atgtcctggc ataagcttct
    15961 ttactccacg gaagaatgta ttttcacctg ctacatatgt gaaagacata taaatctgta
    16021 acatgtcttc atttaactct ttcacaaatc ctggttgctc cataatctta cgaatagatg
    16081 aaccatagag aagcttccca ttttcagtct cataataata gaaaggtttt actccaaact
    16141 ggtctcttag gcagaagagt ttcttttcca cagtatccca taatgcaaag gcaaacattc
    16201 catgcatgtg atttgccata tcatatcccc atgtcttata tgcttccact aaaattgctc
    16261 gttcacgctc atctctacat aatgaagaat cgattccaag ttcttcacag agaactttcc
    16321 agtttcgaat atgtccattg tattctagaa tttttatcat atatgtgtct tttcgtgtta
    16381 aatacttttc ttctaaattt atcatatgtg tatcctttcg tattaaaaca tttaacttct
    16441 aaatttatta aatgtttata tatatttatt cacttataat cactgaaaaa tcgacttttt
    16501 tcaaagtaaa ttctttttga attagtacta atctgctctt tattaatggc ataaatatga
    16561 ttatcaagta ttatcagtgt tataacattg aattttttat tcttcataaa tattgccccc
    16621 tttatattac caactaaata taatatatct tatgttactt acatattctt taagaaattc
    16681 tgaagatttt ataaagtttt ttgtattata attaattaaa aataaaattc tagttataaa
    16741 acatattttc cattaa
//
LOCUS       DAEQJM010000074        16574 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.075, whole genome shotgun sequence.
ACCESSION   DAEQJM010000074 DAEQJM010000000
VERSION     DAEQJM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16574
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.075"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(222..1508)
                     /locus_tag="KRQ43_003060"
     CDS             complement(222..1508)
                     /locus_tag="KRQ43_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH2743402.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAISENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(1631..4729)
                     /locus_tag="KRQ43_003061"
     CDS             complement(1631..4729)
                     /locus_tag="KRQ43_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH2743403.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGINDISHVK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRKKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKFKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFIVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMEVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFDDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDILTGLYN
                     YESFCEQTSLMLKRYPDKSYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDVHKLIYKIKNSLNRKKFEYMLVPCFGVYKILDNN
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLRHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            5453..5605
                     /locus_tag="KRQ43_003062"
     CDS             5453..5605
                     /locus_tag="KRQ43_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743404.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHYPAFAGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(5897..6601)
                     /locus_tag="KRQ43_003063"
     CDS             complement(5897..6601)
                     /locus_tag="KRQ43_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743405.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(6592..8199)
                     /locus_tag="KRQ43_003064"
     CDS             complement(6592..8199)
                     /locus_tag="KRQ43_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HBH2743406.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(8453..9631)
                     /locus_tag="KRQ43_003065"
     CDS             complement(8453..9631)
                     /locus_tag="KRQ43_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743407.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(9857..10351)
                     /locus_tag="KRQ43_003066"
     CDS             complement(9857..10351)
                     /locus_tag="KRQ43_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH2743408.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(10352..11113)
                     /locus_tag="KRQ43_003067"
     CDS             complement(10352..11113)
                     /locus_tag="KRQ43_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH2743409.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            11836..14670
                     /locus_tag="KRQ43_003068"
     CDS             11836..14670
                     /locus_tag="KRQ43_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2743410.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHVSIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNISKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNIRKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            14713..15957
                     /locus_tag="KRQ43_003069"
     CDS             14713..15957
                     /locus_tag="KRQ43_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH2743411.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKV"
     gene            complement(16398..>16574)
                     /locus_tag="KRQ43_003070"
     CDS             complement(16398..>16574)
                     /locus_tag="KRQ43_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBH2743412.1"
                     /translation="TYKTAIDEAQAILDKADATQKEIDDAVTALNTATATFEAGKVPT
                     TIALMLSRILGFMK"
BASE COUNT         5776 a         2739 c         1890 g         6169 t
ORIGIN      
        1 aacaagcttt agtattttta taataatttg ttctagcatt tttaataaca agctctagta
       61 ttttatatta ataatttatt ctagtatttt taataacaag ctctagtatt ttatataata
      121 atttgttcta atttttttca tgataagctt taatacttta tatagtaatt tgttgtagaa
      181 ttttataaaa tataatgatt tatacagttt tataaaatat cttaaaacag tatttcagta
      241 atattttttg gtcttcctcc accaatacta gtctcttttg cacatattcg acctaaacct
      301 gcatttacta ttttatttaa tatacgtctt gcacttcttt cacttacatt tagatactct
      361 gctaactctt ttgaatcata aatcttactt tttctattct cacttatagc aataattttt
      421 gcaactgact cacaactcat tccagtcttt ttagatattt ctattacctt ttcatcagat
      481 agcatcaaag aataatttaa ttcattttcg gaagctaaag gtcctcttat attttcatct
      541 tcatctacca aatatatacc aatttctttt gaatctatgg agtgtcttaa tgctttatgt
      601 gcattatttt cagcctgata cgcagttact ccagtaccaa ttcctatact aagagaaaag
      661 cccatgtctt ttatctctct ctttagattg aatagcttat cataattata ctcattatca
      721 gctacccctt tatgaacaaa tacaacataa tcatttcttc caagtaaaaa taaggaacct
      781 tgaatgcttc ttacatagtt tactacaagc ttatccatat ctgatttttt tatcatgtca
      841 gaataatagt tatctatctt ctctttataa tctattagac tcaatatttc gacagcaatt
      901 tgagaaaatc ttgccttgct tagagcatat tcactcttta ccttatcata actttctttg
      961 attaattgta tagtagcttg taaacgaaat acaggatagc ctctttcttt taattcatta
     1021 tatactgcac caaaaccagt taacattata tccgtcttat tttcttcaaa taattttata
     1081 tgccattcta caagttcaga ctctcctact tccaaagaaa atggattaca aaatacactc
     1141 gttgctttaa tatcaaattc tttaagtgca tcttccacaa catatctatc aactacatct
     1201 atactgaatt tatctaattt tatatttgca ctttttattg cccaaaatgc cttcattata
     1261 ctcgtcccac ttctcggtac aaatgaatgt ggcttactta tctcatactt agattttata
     1321 aattcataaa ctgcacatcc tgtaaatata atagcatcac attcatcttc acatttagaa
     1381 ataacttcta ttgtatctac tactttttct cttacatata ttttagtctt taaatcactg
     1441 tctatctgtt ttaaatcatc ctttatctta aacccagagt ctgaaggacc tataataccc
     1501 actatcataa acttcgctcc taatccataa atattatact ttttaaaaat tatatcctca
     1561 ctattttcta cttctattta attatgttga actactccat cctacctaca tttagagtgg
     1621 gataattagc ttatttttga taaagtaact tctcaaaatc agcacttgga ataggcttac
     1681 aataataata accttgaatt accacacaat ctaaactcac taaaaattca gcttgttctt
     1741 ttgtctctac accttctgcc actacatcca tatctaaatc ttttgccatg gctatagtgt
     1801 gccttaaaac tattttttct ctgtctgtga ttccttcctc attaaagaag ccacaatcta
     1861 tcttcaatgt atcaatatta atatttttta acatatttaa tgaagaatat gctgaaccaa
     1921 agtcatccat atttaaaaca ataccatcca ttctaaggtc ggctattatc ttagtaaata
     1981 attttatatt tttaataaat aaactttctg taagctccaa ttctaaaaaa gattttggta
     2041 tactatattt atttattaaa cttaaaacaa tttctttaaa atgtggatta tgcaaatgta
     2101 atcttgatac atttacagag ataggaactg gctcttcacc taaatctatc cattttctaa
     2161 tcaaagaaca tacttgttcc cacacataca tgtctaatct gataataaac ccattcttct
     2221 caaatagtga aataaattta attggaggta ttataccttt ttctggatga acccatctaa
     2281 ccaatgcttc cgcaccaaca attttatttg cattaagatt atacttaggt tgtagatata
     2341 catggaattg cccattttca agtgcgtatt ccatttccct ttccatctgt ttttcttcaa
     2401 gtgcatcatt tcttatagta tcatcataaa atatatagtt attgatactt tgtttcttta
     2461 cttttttgtg agcatatcct gccatttcac acgcatttgt aattggaata ttattatcca
     2521 aaattttata aaccccaaaa catggtacta acatatattc aaattttttt ctatttaagc
     2581 tatttttaat cttataaatt aatttatgaa catctctatc agagtaactc tcataaaaaa
     2641 tacaaaatac atctgcatac atacgacaac atataccatt agaaccaatg tttttttgaa
     2701 tcaattctgc aacatatatt aaagccttat ctcctcctct aactccataa atgtcattaa
     2761 ttaccttgaa cttatctata tccatcatta taattgcata gctcttgtca ggatatcttt
     2821 taagcattaa acttgtttgt tcacaaaaac tttcataatt gtatagtcct gttaatatat
     2881 ccttttggtt tttatgtagt tgcataagat aatctatatt ttttatagca actaaaatat
     2941 gtgtttgttt ctcacctaac ttatttttac tactaatctt taacatataa attaatgccc
     3001 aatagtactt tttatctatt cctaaacgtc tatactcaaa atttagttct aaatcgtctt
     3061 gcttgctgtt attaagacta tcaagagatt ttagaaggtg gttatcatca aataatatta
     3121 tatcatcagg atgaattaaa tgttttttta tgtatgaaaa agttttttca agattttcct
     3181 ttataggaaa actaaaaata ttgctctctg attgataaat tggagtaatt aaattagtat
     3241 cgatgcaaat agataaaatt atatcatatg tattataagc taatttttca taagccttag
     3301 aatacccttt tatcattaaa tcatcaaaat aaaccttatc aactaactct ttatgtttaa
     3361 ataaaatatt attcgtcgaa tcagctaagt cactaattac ttccatttca ttatttctaa
     3421 gtttgttctt attataatac ctcttcttat cttggtacat tctctcatca gcaactttaa
     3481 ttagcttatg tatatcaata ttatcgtcac tccaaatact gcccactgct acactatata
     3541 tcatctcatc cttaaattct tcacttaacc aactcactaa ttcttcaaat agttgttttg
     3601 atatatcttc acataataca ataaactcat ctcctccaat acggtaaaca ttataagaat
     3661 gaaagtattt ttttattatt acacatgctg acacaatagc agagtcgcca ttagcatgtc
     3721 caaagttatc attaatatct tttaacccat ttatatctac aaatacaact cctatggatt
     3781 taaattttcc tttttgaaaa ttatctatat acttaatata tttgtttcta ttatatgcac
     3841 cagtcaagaa gtcatagtag ctcatataat ttaatttatt ttctactttt ctttttttca
     3901 tctcagttaa taaaaaataa gatagggatg tcaaaagaga ggtatctcca acagccttat
     3961 gtggattatc aactccaata aaccctacta ctttatcatc ttgttttagt gaagatgtca
     4021 ttaaactttc aattttttga ggttttaaaa tttcatattc tattggctgt tcttctttta
     4081 tattttctat atcatcaatt attacaaaac ccttttgttc gaataataaa aaccaattct
     4141 ttaattcatt aatatcaaga tttgttagtg cctgtttttg ttcatcaaca ccttcattgc
     4201 accattcata tgtattagtt actttttttc tatcttctga tacttcaaaa acatatgctc
     4261 tatcagcttt atgaaattta ccaatattgg ttaatacaag atttacagca tcagaaaaat
     4321 tagattctgt tataagatgt ttaatacatc caactaataa ctcctttatc tctaattttt
     4381 ctgctattga cttacttata tcttcctttt ctgtaatatc aagagctatt tctaatcgtg
     4441 catgtttgcc ctcccattta attaacttgt cctttaatat aaaatgtcta tttgttcgag
     4501 tattcgtatt ttcccatatg taatattcat cttcttttaa aatagagttt gtacaaaatt
     4561 cgcagggaga atctttcccc tgtaatgctt tataacattt tacatgggat atatcattaa
     4621 ttcccattgc ctttttccca atttcattaa tatataaaag ttcatatgta tctaaagaag
     4681 aaacatatac aatttcatcc aactcatcta ttaaatttat tacatccatt tatatatatc
     4741 tccttttatt cattttccag attgaatttt taaagctttt aaaattttgc tatatatttg
     4801 gcaatgatat tatacttctt tatgttttaa aatagtacct taataaagtt ctatttttta
     4861 gtaaatagaa ttattattgt gtcaatcgta caatagagtt ttgtaatacc taatttaata
     4921 tatttataat taactatctt attatgtgtt tacaattaat tctcatataa atgacaaatc
     4981 tccacctcaa ttaagtattc caatcatata tgaagataat acttcattca tttaaaaata
     5041 taaaactatt atatattaaa atttcttcaa taataaatta tctagattgt tactttgata
     5101 tattatataa tatcacaaag gctgatataa aaagacaaaa agggtaattt ttttatatca
     5161 aaaaaaatgt taaattgata ttatccatat ataaattgat attatccata tagatgctat
     5221 atttaacaat tctacttact tcccttacac ttattagcat atagttatta agagtttgtt
     5281 gcaaaacaac acttagcaca ctttaaaaag tgtggtctaa taagtaatca acgaagaaga
     5341 cataataaag cataaaatat gatatacttt tcctgtcatc aaaactgatg attttactat
     5401 taatatctgc taaaatatgc ttaataaatt aaattttagt gggagaatag ttatgaaaat
     5461 atttagtttc ttgttgtttg tagtgggaat atgtttttgt attgctggat ttatgggaca
     5521 ttacccagca tttgctggtg caacattgag tttttttgca actacaatga tagctgtaag
     5581 acaagtcaaa actaagaaaa aatgaaatag gcaaatccta actttacaag ttaatattac
     5641 ataagtaatt agtctaaaat tggatacttt ttctattaca gaaatacatc atccactttg
     5701 tattctctta aaaaaataaa atagctatgt aaattcaaga ttagatagat taactctcta
     5761 tccatttcat tgtaaaatat acatagctat ttgtattcga tttaaaatac ttagattttc
     5821 ttacataaca aataatttct atctgattat tactcatatt catttagtaa tcactcagca
     5881 actaatcatt tagtatctat tcatccgcca tacggtaacc taccccaacc tcagtcaaaa
     5941 tatattctgg ctgagcagga ttcttttcaa ttttccttct tatacttgcc ataaaaactc
     6001 taagcgactg attttcactt tcatagtaat ttccccaaac tttatctatt ataaacttat
     6061 gagttaagac tcttcctgaa tacttagaca tcaactcaat aatcttatat tcgattggag
     6121 ttaaatgtat ttcttcacca ttaattgaca caatatgatt ttcataatct atctttaggt
     6181 ttttaacttc aaaagacttt ggagcatcat tatttatatt atcctgttga gctttatttc
     6241 taagagccac acgtactcta gccaaaagct ctgttacact aaaaggttta gttaaataat
     6301 cgtctgctcc tccatctaaa gcttccacct tatccctctc atgctctctc gctgaaacaa
     6361 caattatttt attagtcttt gcacatgccc taactcgtcc tattacctca atcccatcaa
     6421 tatctggtag tcctaaatcc aaaattatca aatctgggtc aagagaatgt ataagtgata
     6481 tagctgttcc tccattatct gtctctacac acctataatt ttgagtttca agagatactt
     6541 ttataaattt acaaattggc ttatcatctt ctacaattag aactaatggc tttatttcca
     6601 cttgtctttc ccctcctcat catacatagg tatgctaaat ctaaatgtag ctcctccaga
     6661 aggattatta aatgcgacaa tttctccacc atgagcttct actatagatt tacatatctc
     6721 caatccaaga ccaatacctc ttctttcaag atttctagac ttattcttag tataaaacct
     6781 attaaaaata ttaccgatat cttcatttgg tattcctttt ccattatctg caacttcaaa
     6841 tagcacttga tttgactctt tttttacagt tagttctatc ttagaatttt taggtgtatg
     6901 ccttatagca ttatcaatta aatttactaa cacttgttct attaataata catccacatg
     6961 aacgattatt atctcatctg gaatattggt ttttatgtct ctactattgg caaacttttt
     7021 gactcttaat atagattcag ctattatttc atcaacaact tctggtcgtt tttcaatatc
     7081 caatttccct tcatctattc tagtcatact aagtatattc tcaacagaat gagttagcca
     7141 actcgtatct tcatatatat ttttcaataa ttctactcta gtttctttat ctatcacatc
     7201 atcattttca agtattgttg aagacgaacc caatatactt gtaagtggag ttcttaaatc
     7261 atgagaaatt gacctaagca aatttcctct taatctctct ctctctgcct caagatttgc
     7321 ttttttattt ttctcaaata aattttctct atcaattgcc aacgcaacct gtgttgaaac
     7381 tgcttctaat agtatctttt cattttctgt aataatatct atcttaaaac acgcaacacc
     7441 tataacacca agaacatttg attcttgacc ttttataggg aaataatatg cactgctgtt
     7501 tttgcaatat tttgtcccaa ttccaactgg gttacctgtc ctaaaagctt cttttatagc
     7561 ttctttttct aatactgaat ggaatatatt ctcacttcca tcattgttac aaatataaat
     7621 acttggctta cctagattat tattctcatc tgcaatagtc actattacag ttctatttaa
     7681 tatatttact aaattagacc cacaaaattc aataatttga tttttatttt ttgctttaag
     7741 caacgttttg ttattctcat agagcaatct tatcattttt tctctcttat gagaaagtct
     7801 cacttctctt tttatcctag aagttaaagt acttgttata attgctgcca ttagcataat
     7861 acaaaaagtc ataggataat cttttctata agctaaaaaa gtatataatg gatgcgtaaa
     7921 gaaaaaatta aatgatagca ctcctattac tgaagaaagt attccaaaaa aatatccata
     7981 ggttatactt gtagcaaata gtacacctaa tatgtatact agtataatat tagattcatt
     8041 aaaacctacc ttttcaaaaa ctactgatat tccagtagca attgtcataa ccaatatagt
     8101 ttttatgaag tccttaataa ttatcttttt actgagatag ccatcttcat cataatcata
     8161 ctcttttaag tcttcatgtt gtagtcgttc ctttttcatt tactacaatt cctccttatt
     8221 gttactgttt aaattggctc tattttatat aatacaattt tatcataata aattcaatca
     8281 atacatttaa ttaatgtact taaattacta aaaggtgctg tcttaaaatg aaaataaatc
     8341 tctatttcaa aacagcacct atatatttaa attactaatt tagtttttac atacttaaat
     8401 caatagtttt attcaatttt ataaattata atacttcaat tatggaacat ttctatccaa
     8461 caagcataaa tataaagtgg gcacatatac ctgcacacaa accacctatg gtatgcgaaa
     8521 gtatcgcttt accagccaat ggtcttgcat ctaaagcatc catcatacct atgtgtgtac
     8581 ttaaatatcc actccaacac atacccattg ctgtgaatac tgctatatca ttaggagtta
     8641 tagcgcctga ttttataaac tctggtacta aagatattgc tgctccaaca gctcctaatg
     8701 cagttacagg gaatgctatt gcctctggtg atgtgaatcc aaataatggt tctattatga
     8761 agctaatctt atcaccaata gcaggtaata attttatacc ttcatatgca gctcctgtgt
     8821 aaacagcttg acctgtagca gggtctgtag atggtccaaa agttaataac ataactaatg
     8881 tacaaactac taaaactcct ggtattatag ccatacccat ttcaacacct agcttaccac
     8941 cttcaagtat agcatccaat gttctttgga atacattacc atctcttatt tctctaaact
     9001 cttcaagttt tgcaccttta tcatttattt gcttttcagt atcattttta gggtcataat
     9061 tataatactt tttagtaaaa gtcaacataa ttctaacact aataatacta cctattattg
     9121 ccccaacatt acctattata gctggtagta catattcttt accttgagct atcataaaag
     9181 ttgttacaat aagtcccata ccaaaggctg ttcctaaatt acataaagca ggtacttgat
     9241 acttcttaaa atattgtgta aatgttttgt ctttagcaaa tggtataata gctggattat
     9301 cagataaata tgttgcaact actcctgcta tactagcacc aggtaagccc catataggtc
     9361 tcataagacc cttaaatatc ttattaacta aagatattac tccaaactct gaaagcaacg
     9421 cactaagtgc acctgcaaga actgccatag ccattattaa aaatactgtg tctaataaaa
     9481 gcgcatgtgc tgtactcatt attactttaa acatcattcc tgcacccatg atgcttccta
     9541 catatccaaa tcctaccgcc aatagtacaa taaatacgaa ggtttccata cttactgcct
     9601 tgactcttct cttatccgac agcttttcca tcttgaaatc ttcccccttt taattttaaa
     9661 ttaaggttcc taacattggt acaaattttt tggtacaaac tgagttctaa aacttacact
     9721 cgtaatgcaa gttgtcagtt ttttgaaata aaaaaaaatt acgtttatag aataagaata
     9781 tcctctttaa tttggatact cttattctat tttatgttat tatattatca tccttttgtt
     9841 taaaagtcaa ttttttctat ttttgttgtt taattttatt tatactcttt ttatattttt
     9901 cattttcttt tatctttgta agcactccat ataagttgac ttttctaaat acagtagtta
     9961 taaataccaa tcctaatgca attgaacttg cacatgataa tgtactcacc ccatattcta
    10021 cagcttttat ataattattg gtcaaaacag aatacatagt attatatatt ccataaccag
    10081 gtactaatat tattaaacaa caaacactta atgtagttgc tggagtcata taaattcttg
    10141 cacataactc acaatatatc gcaaaacaaa ctgtagctat aaaaaaacat aagttttctg
    10201 ttactcccat atttaaaaga aatttatatg aaaaccaagc tatacttcca cctattcctg
    10261 ctagtattaa gttttttcct ttcatattaa atagcactcc aaagcttaag gcagtaaaaa
    10321 aagctgctat tacttctata aacaaatgca cttatatccc ccctaacttg aagtataatc
    10381 caagtaccaa gaacattcct actgctatag atacacctac aaaaaatact tctgctaatt
    10441 ttgcaagacc agaaatcaac tgtccatcta acaaatctct taatgcatta gtcaaagcaa
    10501 gcccgggaac taagagcatt attgctcctg ctattaaatg gtctaacgtc tttataaatc
    10561 cgagctttaa aattaaaatt gaacaagaag ctataataac tgctccaatt gcatttacaa
    10621 aaaagtcatt aagtgaagat ttacttaaat acataataac aaacttagtc agaatcccaa
    10681 cagtaaatgc agctataaat tcttccacat ttcctccaaa taatatcgaa aaagttgctg
    10741 ctgcaatacc tgcaaaaaat attgttatta aatccgagta atagttatct tcacttattt
    10801 catctaaaat tttctcacat aattcaatat ctaaattatt tatacttatt gctcttgata
    10861 atgagttaac ttcatgaacc aagtttaggt ctactcttct tgagcttatt cttttaattg
    10921 ctgaatgtaa tttcccatct acaaatacag atgccattac agctgttgga gttgcaaata
    10981 catctacgtg gtctattcca aaagattgac atattctagc tatcgtttct tcaactctat
    11041 aggtttctcc tccactttgc aacatagctt tacctgcatt tgaggaaaag tttaaaattc
    11101 tatctatatc cacaaaacat atctcccatt cttttatagt attattcata ttttaataca
    11161 agatattatt tatttaaact attttaaata attcatatcc aatatttaca ttttatgaaa
    11221 aaacttgttt tttatgcttg tcaaaatcaa attttaagct tgtttacacc ataaaatggc
    11281 tgaattaata tttgacaaac actttcaacc atttatataa ccttctaaat tgtataactt
    11341 tttactacaa ataaaattat atctctttta attctttctc ttgagtattt aagcttatag
    11401 caacttcata tttatatatg tacaatataa aacattattt ttatgataca aaatataatt
    11461 tgtaaacgta tatatgtatt aactgtgtat atataaatta ttcttaacct tatcagtttt
    11521 ttcatatatc ttcatctata tcgaccatat attaattaca ttgaccatat actaataaat
    11581 gatattacat agactgaagt atattaaaaa acttaaattt agttatttaa caacataata
    11641 ctctaattta atctataaaa atccatacct aatataatgc aactcttatt ttaacaccat
    11701 ctattacaca aaacaacata ttaaaaagta aaatacaaaa tatccactat aaaccttatt
    11761 ttaatactga atatatatta taatatattt aatgtagctt aaatatagtt taaacataaa
    11821 gaaaggaaat ggtatatgct aagaaaagat aaagttctat tatctctaca taaattatgt
    11881 gaaaatatga ctttaaaaga ccttcaatca gataaaacag gattcactac aatagaaatt
    11941 gctaaccatt catctcttga tagaagtaat accagtaaag aattaaataa cctatataat
    12001 gaaaaaaaag ttctgaaaat atctggtaag ccaattttat ttctacatgt tagtattata
    12061 gaaaatttaa ttggccgtac tttgaacagt gatgaatttt ctataaataa ttgtaatgag
    12121 ctacttaaat caagtaaaaa tgactcagaa gatatttttt caacattact tggacatgat
    12181 tctagtctta aactacctat agaaaaagct aaatctgcta tactctatcc tccaaaaggt
    12241 cttaatacgt tactcatagg acctactggt gttggaaaaa gtacatttgc cgaaacaatg
    12301 tacaaatatg ctgtagaaag taaaatcttt tcttctgaaa gcaaattcgt agtatttaac
    12361 tgtgctgaat atgcagaaaa tgctaactta ttattaagta atttatttgg ttatgtcaaa
    12421 ggttctttta ctggtgctaa taaggataaa ttcggcatag ttgcacaggc tgatggaggc
    12481 atattattct tagatgaaat acacagatta ccaccagaag gtcaagagat gctttttctt
    12541 ttgatggaca aaggcatata cagacgatta ggagaatctg acattgtgca caaagctaat
    12601 gtctttattg tgtgtgccac aacagaagat atacattctt ctctgcttgg gactttttta
    12661 agaagaatcc ctgttacaat caacctacct gctttacagg ataggtcttt aaaagaaaga
    12721 ttatctctta ttaaatactt ctttattata gaatcaaaat acaccaatgc aactataaaa
    12781 gttcacaaag atgtaattaa atcattactc ctttatgatt gttttggtaa tataggtcag
    12841 cttaaatctg acatacaact tatgagtgca agagcctttt taaattacaa aactggactt
    12901 aaggataata tagaaataga tttatccctt gttcctgatt acatctatat tggtctttta
    12961 aaattgaatg aaaatcgtag taatctaaat aaattatcag aacttgatta tatgcttttt
    13021 tatgaattta atggtaataa cttagaagtt gaatatacaa aagaactatc taaatacaat
    13081 atagatacat caaacaatgg atttaaatac tctacagaga ttccttatct ggaaaatgat
    13141 ataaggagta tgtttataaa ttacatggaa aagtactcta caaaattact ttcgatatct
    13201 tcagtaactc attctgatta tacaagtaat gaaattttta aagtaatcaa tccaaagatt
    13261 tactatgctg ttgaacattc tttaaaagag gccgaaaaaa tatcgagaaa caaatacaca
    13321 aaacaaactt atattgctct ttcaatgcat ataagtgcac ttatagaaaa tataaatcaa
    13381 gacacctata atcctaagta caatttatat aatgataaaa ttttcttaga taaagattta
    13441 aatatatcta aaatagtttt aagtataatt gaaaatgact tacaaacatc tttacctaaa
    13501 gatgaagtaa aatttatatc catgtttcta aatagcatgt atcttgaacc aaacaatcaa
    13561 tctgaaagta taggagtcat aatacttgct catggaaatt caacagcaag cagtatgtgt
    13621 gatgtagcaa attcattgct tggtacaaac cattgtaatg caattgacat gcctcttgat
    13681 gtaaaagtaa gtaccatact tgataaaact atagagttgg taaaagaatg tgacgaaggt
    13741 aagggtgtac ttcttttaac agatatgggc tctcttatag cttttggaga acttatttca
    13801 gaaaaaacaa aaatcaaaac tcgctcaatt gaaatggtat ctactccaat agttttagaa
    13861 gcagtaagaa aaagtacatt accagaaatg actttggatg aattagctaa ttccttaagc
    13921 tctttaaatc catatattgg acgagcagca atcgattcaa cagaaataaa ctatcctgaa
    13981 aagtcaagag agtatgtaat aataactact tgtataacag gatatggttc agctatgaaa
    14041 gtagcagact ttataaattc ttcacttaaa aatattcgta aatacaatat taatttagtt
    14101 cctcataata tagaaagttt taaaatgtat aagaataaat ttagtaatac taaaattctg
    14161 gcagttgttg gaagtgtaga ttttaatgta gccaacaccc cttttataca catagaggaa
    14221 ttactaaatg gatatggcct agatatgcta aacaaaataa tagaaggtac attcaatgcc
    14281 aatagtatta caaatataaa agaaacaaat ctatcataca acagtttaat aataaacttt
    14341 atgacccaaa acttagaact tttggactct gttaaattat tcaactatgt caattcttcc
    14401 ttatttacaa taatagaatt aatagatgaa aacttaaaga gcaaatttaa gctaggatat
    14461 atactacatt gctcttttat gatagaaaga tgttttaaaa atacaacttt tccatataat
    14521 aacattactg aattaattag taaaaatcat gaactatata gtttaatacg tgaagccttt
    14581 aagccaacag aagcttattt taatattttg ataccagacg aagaaattgc ttatataata
    14641 gacatgatta atgagtatct aaataaataa aatttatagc acttattttg tgcatattaa
    14701 ttaatatatg aaatggagga cgagattttg aaaggaaaaa taaaacagtt aacaatactt
    14761 gcattaattt ttatatttat aactcctgta tttgcatttg cagatactcc accagtacca
    14821 aattcttcaa gagcagcact acttatagac caggaaacta aaagaatatt atttgaaaaa
    14881 aacattgatg aaaaaatgcc attagcgagt ttaagtaaaa tgatgacctt tttattggca
    14941 atagaagcag ttgataagaa tcaagtaaaa gagactgata tggtgaaaat agacaagtct
    15001 acagcttcag taggaggttc tacttgtaaa cttaaagatg gtgatgaaat atctctagga
    15061 gagcttatgc agggtctaat gctagtatct ggaaatgatg ctgctatagc catagctaaa
    15121 catattggta agactgaaaa gaattttgta aatatgatga acaagaaagc agaagaaata
    15181 ggaatgattg atacgtatta ttttaatcca aatgggcttc ctatatatac tgacccagaa
    15241 cataaagaac ctcctattga aaatatgtca actgctcacg atatagttac acttggaaag
    15301 tatatgtatg accattatga aaatcaagtt acaagaataa ccactatgca agtatataat
    15361 gatactaaaa aggattttac acattataac acaaatcccc tacttgtttc agtacctggt
    15421 gttgatggaa taaagacagg ctatacagat aatgctggat attgccttgc attttctatg
    15481 atggtaccta aagatgctaa aaacgaaaga aatcatagat tgataggtgt tgtacttggt
    15541 gatggtaaca agaaaaatag aatttcttct tccgctactt tattgaaata tggtaaagat
    15601 aatttccatt ctaaaaagat agcacataag ggtgatatta tagagactcc ttgtgttgat
    15661 ggtattgatg attttaagat aacagttaag gttgataaag atttgtatgg tgttgtttca
    15721 gataacgaaa atatcaatcc taaggtagtg tttaaaaata tgaattatcc tatccataag
    15781 ggagatattg ttggtgttgc aaagtattat aatgactctg gtaaatttgt tggaagtgtt
    15841 gatgtaaaaa gtgaaagtaa tataggatgt attcctttga aggataagat taagattaag
    15901 gttgctaaga taaataaaaa acttgagatt aaaaattctg tttgttttaa agtatagtaa
    15961 agcatactat taaaagagta tattaaattt ataaatactc cactttgtgg agtttttttg
    16021 ttttttacaa aaaattaaaa tagtggcaac aattgaggat gtgagggaga gttgccacta
    16081 ttttgtatag ggtattatat tatgttttta agctagtttt actatcttct atgtttatat
    16141 aataactctt gtgtgtgaat ttaattgata attaatatga aaattatgtg aagttttgat
    16201 attaggttat actttgaact ttatctaaca ttttaaattt tatatctcta aattatctaa
    16261 aattactata tcaattaact ttacatgata aaaaggctgt gtataaattt atttttaaaa
    16321 attttactca cagccttaaa ttaaattttc tatttaaagt atatataaat tttattaaat
    16381 aatttgcttt ttatttctta tttcataaat cctagtattc ttgataacat taatgcaatt
    16441 gtagtaggta ctttccctgc ttcaaatgta gctgttgctg tgtttaatgc tgttactgca
    16501 tcatctattt ctttttgtgt tgcatctgct ttatctaata ttgcttgtgc ttcatctatt
    16561 gctgttttat atgt
//
LOCUS       DAEQJM010000075        16225 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.076, whole genome shotgun sequence.
ACCESSION   DAEQJM010000075 DAEQJM010000000
VERSION     DAEQJM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16225
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.076"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            474..1124
                     /locus_tag="KRQ43_003071"
     CDS             474..1124
                     /locus_tag="KRQ43_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2743413.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            1402..3468
                     /locus_tag="KRQ43_003072"
     CDS             1402..3468
                     /locus_tag="KRQ43_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH2743414.1"
                     /translation="MKEVVESLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYVWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYIYDSNINKLKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNICILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSSMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            3485..5440
                     /locus_tag="KRQ43_003073"
     CDS             3485..5440
                     /locus_tag="KRQ43_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH2743415.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKEAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDR
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGIDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLERSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            5456..6646
                     /locus_tag="KRQ43_003074"
     CDS             5456..6646
                     /locus_tag="KRQ43_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH2743416.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            7780..8154
                     /locus_tag="KRQ43_003075"
     CDS             7780..8154
                     /locus_tag="KRQ43_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2743417.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFVSTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMGILYEED"
     gene            8156..9013
                     /locus_tag="KRQ43_003076"
     CDS             8156..9013
                     /locus_tag="KRQ43_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743418.1"
                     /translation="MENILEVYNLNKTYTNFSLSNISFVLPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMSEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTEYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDEIKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            9016..9654
                     /locus_tag="KRQ43_003077"
     CDS             9016..9654
                     /locus_tag="KRQ43_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH2743419.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVMIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            10628..11362
                     /locus_tag="KRQ43_003078"
     CDS             10628..11362
                     /locus_tag="KRQ43_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2743420.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEVSYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMVLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELTPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRDIIGTLKNLIIE"
     gene            12504..13760
                     /locus_tag="KRQ43_003079"
     CDS             12504..13760
                     /locus_tag="KRQ43_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH2743421.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFLLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGIAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKTLGLEKFS
                     FALSSKVVFDLPIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            13823..15016
                     /locus_tag="KRQ43_003080"
     CDS             13823..15016
                     /locus_tag="KRQ43_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH2743422.1"
                     /translation="MLTSLALIFLLGMASGGIFEKIKLPSLLGMLLTGIILGSYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMNIGIFLQIKYRVVARRLSVKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGIASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     EGKSK"
     gene            15223..15603
                     /locus_tag="KRQ43_003081"
     CDS             15223..15603
                     /locus_tag="KRQ43_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH2743423.1"
                     /translation="MYLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKILSKLSKKRFLYVQETGKCMYYTVAIKEKTYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYI"
BASE COUNT         6032 a         1778 c         2820 g         5595 t
ORIGIN      
        1 caaattatta agagatagta aatatttata gtttaatttg tagtacacta gcatgatttg
       61 cagaacaatg aattaatcta tagtataata gtttaatttg aagtacaacg atttaatcta
      121 tagtacacta gcatgatttg aagtataacg atttaatcta tagtacaata acttgatttg
      181 caatacaata atttaatcta tagtataata gcatgatttg aagtataacg atttaatcta
      241 tagtacaata acttgatttg aagtacaacg atttaatcta tagtacaata acttgatttg
      301 caatacaatg atttaatcta tagtataata gcatgattta cagtacaata atttaaattg
      361 tagtacaaaa gtactatcaa ataagaattt ctactttaaa aatattacta aaagtaatta
      421 aaatccaata attcaatata atatggcaaa agaatagaaa taaggtgaga gtagtgaaag
      481 taaagtcaaa tttagatgaa attttatatc ataagattat tgaaagtctt attcgtggtg
      541 aatactctgt aggtcaaaaa atattactaa atgacctttg tgaaaaattt gaagtaagca
      601 gaacaccagt tgtacaagca gtaaaaatgc taaataaaga tggagtgctt actattatga
      661 caaatggtaa agtgtacgta ccagagtatg aatatgatat ggtaaaacaa gtttgtgaaa
      721 cgagaacact gattgaaaca tatgctttag aaaaaatgat gcaagaagag gaagaggttt
      781 ttcaacaaaa gctagatgta ataaaaagat actctgataa atgcgaggag tactatcgtc
      841 aagaaaaatc tgtagaactt gcactagcag atttggaatt acataaagcc attgtagaag
      901 gggcaaataa tgagatttta aatgatgtat atgttggtat acaaggaaga tttatagtag
      961 tgaactattt aattcgacca ttaaaaaatc gtaattatga aggaacagta caagaccatt
     1021 ttgaaatatt aaaattcatt gaagacagag atacaaaaaa agcagtagat aaactaagaa
     1081 atcatattca aggaactatt aaaagattct gtgaagatga ataataagtt ttgaagttac
     1141 tatatactta tctattaagt tgctaaatgt agtctaagta taatctaatt atagtttaaa
     1201 cataatctaa atataatcta aatatagtgt aaataagtct aagtatgaat taaatataga
     1261 ttaagtatga attaagcatg gattaaatat actttaaatt acaaatatta caaggaagcc
     1321 agaaggcttc ctaaaaaaat aacctttata aaatttttta ttttaaattt aaaatttttt
     1381 attttaaatt taaaataaaa aatgaaagag gtggtagaga gtttgaaaaa aattactaaa
     1441 gaaaggatag aaaatactat gaaaaagcta tttacgagcg aaacattttt ggaatatcaa
     1501 tttataagtg attgccaaat atcaccagat ggaggatata cagcatttat tgtaaaaaaa
     1561 gctgatatca aagagaatgg ttacacaagc caagtttata tattaaacaa taaaactggc
     1621 gaattaaaac aaataacgtc tataaactct gttggagcat atgtctggga agatgaaaat
     1681 actatcttgt tccctgcttt gcgaaatgaa aaagtaaaag aagctgtcaa aaacggtaag
     1741 caatgcatga gttactatgc tttatcttta aatggtggag aagcagaaga actttttaga
     1801 ctccctatca aaggtggtaa attgaatcct ataggaaaag gtttgtatgc agttattgat
     1861 tcttatgaca atgaccgacc tattgtagag ggattgccag aagaagaaca acagaaaaaa
     1921 ataaatgctt ataacaaaag acattatgaa catttcaaag aaattcctta tgctgtcaat
     1981 ggggagggat atattagcag aaaaagaaaa cgcctatata tatacgacag taatataaat
     2041 aagttgaagg caattacagc acctatgttt aatgttgtag gtatgaaaat aagtgatgga
     2101 aaaatcttat atatagggca agagtttaaa gatgtaaaag gtttgaaaaa tggggtctat
     2161 gtatttgata caaacacaaa cacaaatatc tgtatattag aaaaagataa gtatattata
     2221 aaaggttttg aattatatca aaatcaagtg atactaaacc taactgatgc tttatcttat
     2281 ggaaatggag aaaatggaga tttttatact attgatattg atacgaaaga aatgaaactt
     2341 ctttcagggc atcaacatca ttgtattgga aatacagtaa catctgatgt taaaatgggt
     2401 gctggtcaga caacaaaggt agatggagaa tatatttatt acacttctac agtagatatg
     2461 gactgcatta ttgaaagaat acatattcca acaggaaaac aggaaaaagt aacacagaca
     2521 ggttcagttg attttataga tgtaaaagat ggcaatattg tatgtgtggg ttgtttagga
     2581 aatggattac cagaagttta tacagtagag aatggaacat tgtgtaagaa aacacattta
     2641 aatgaccata ttttagagga atataaaatt tctgtgccag aatacataga gtcaaaagga
     2701 agttctaaat gggaaataca aggatacgta tataaaccag tagattatga ggtggggaaa
     2761 aaatatccag ctgtattggc gattcatgga ggaccaagat tgacatatgg accatatttt
     2821 atgcatgaga tacaggtatt tacaagtgca ggttactttg tattcttctg taacccaagg
     2881 gggtctgaag gtcgtggcaa tgcttttgca gatattagga aacagtttgg agatattgat
     2941 tatatagatt ttatggaatt tacagatact gtacttgaaa aatatacaga cattgataaa
     3001 acaaaattgg ctgttgaagg tggaagttat ggtggattta tgacgaattg gataattggt
     3061 catacaaacc gttttgctgt tgcttgtgct cagcgttcta ttgcaaactg gagtagcatg
     3121 gagggtacaa cagacattgg ttattatttc tgcaaaggac aaacaggtgc ttctcatatg
     3181 gaaaaccacg agcttcaatg gaaacagtca cctcttgctt atgctgataa atgtgttaca
     3241 ccgactttat ttttacatgg tgaaaaagac tatagatgct atatgcaaga agcattccag
     3301 atgttttcag cattgaaaat tcatgggtgt cctacaaaac tttgtctatt tgaaggggaa
     3361 aaccatgaac tgtctcgttc tggtagacca aaacaaaagc tacaaagatt agttgaaatg
     3421 ctagattggt tttctgtgta cataaaaaaa gataacatag gacagtagaa aggagaatat
     3481 aaaaatggaa aaaataaaga ttgaaagttc agatattttt gaatatatat tccctcatga
     3541 tatttcttgt tcacctgatg gaaagcatat tgcttatatt atatcaaata tcaacgagga
     3601 aaaagactgc tatgaacatg acttatatgt gatggacatc aaaacagaaa aacaaataca
     3661 tatgactcaa acaaaagatg taacatcatt tagttggatt tctaatacag aactactttt
     3721 tacatctaaa agaaataagc caaaagcagg tacaacagat ttttacacta tttctataga
     3781 aggaggagaa gcaaaagaag cattttctat tccaaaagct tgtagcgtac ctgtatcact
     3841 tggaaataaa ttgtggttat tgacaacaaa aaatccaacg gattctaaaa aatcagaacc
     3901 agatagggca gtagagggtg tagattattg gacatttaca gataaacctt ttataagaga
     3961 tagagaaaat ttttctcaaa gaagacgtgt aacattagaa ttatatcaag aaggtgaaaa
     4021 tataacaaaa gccattacac caaaattttg tgaagtagca ggtatagacg tttcttctga
     4081 taaaaacaga attttatata ctggtcagat ttatgaagat tgtgcaactc ctttttctgg
     4141 actttgggag tatcatatag acagtggtga aaccaaagaa cttgtaccac aaggaaagta
     4201 ccaaataagt ttggcaaaat atattggcaa agataaagta atgttgcaag cttcaacatt
     4261 agaacgttct atcacacaga atcatgatat ttttatactt gatttgagta ctagtgaaat
     4321 aaatatgatt gctagtccag atggtatgta tgctacatta ctggatgtag atgcagtata
     4381 tggtggtgga cgtagtaata aagttatagg agataaattt attggtgcaa gaatttgcag
     4441 aactatgaca gaatttaatg agtttgatac aaagacaggt aatatacgta tcatcacaaa
     4501 agtagatgct tttacatctt ttgatattta cgacaacacc atgtacacag taatgttgaa
     4561 agattatgag ttagcagaaa tatatagcat tgatatgact acaggtacaa tgaaaaaaat
     4621 gactgctttt tctaaaccat atttagatac tcataaggtt tcattacctg aaaaattgac
     4681 gtttgtagca aaaaataaag aagaagttga tggttttgtt ataccaccta tagatgctaa
     4741 agaaggcgaa aaatatcctg ctgtattgtt cattcatggt ggacctaaat gggcatatgg
     4801 ctatatgttt acacacttga agcagtgtgt aacatcaaag ggaatgtatg tgatttattg
     4861 taaccctcat ggtggtgacg gttatggtga aaaattctta gaaatggtag aaagatgggg
     4921 gtatgttgac tatgagcatc ttatggaatt tgtagatact tgtattgaaa aatatcctgg
     4981 gattgatgca gaccgcttag gggttgcagg gggaagttac ggtggttata tgacaaactg
     5041 gataattggc catacagacc gtttcaaagc agcagtttct caaagaggta ttagtaactt
     5101 gattacagct tctttaatta ttgactttgg ggatagaatt atgaagcaga cttgtggaga
     5161 taagacgcct tggaatcatg aggaggttct ttggaatcat tcacctatta aatatgtgaa
     5221 aaatgttaag acaccaacat tgttcttaca tagtgatagg gattatagat gttttatggg
     5281 ggatactttc caaatgttta cagcattaaa acagcttggt gtagatacag aaatgtattt
     5341 gttccatgga gatacacatg gattgtctag aaatggaaga ccatctaata gaattgcacg
     5401 agcaaatgct attgtagatt ggtttgaaag atatttataa taagggggtt attctatgag
     5461 tgatatgtta ttatggttta gtgtcgtatt agttttattt gctattgggg atttaattgc
     5521 aagcaaaaca aaagcaaaag tatcagctgt atttgttaca ctacttttat ttttgattct
     5581 atttgtcaca aaagcaatac cagctgatat tattgaaaaa gcaggtatga ccgcagcagc
     5641 tagttggagt gttccaatga ttatgtttag tatgggaaca atgttgaatg ttaaacaatt
     5701 tatagacgaa tggagaacag tattgacagc atggcttgga attgtagcag ttatagtctg
     5761 tgtctcatta tgtattcctt tgtttggaaa atcaacagta ttgacaagca taccagttat
     5821 aaatggagct ttacctgcta ctactattat gacacaagca gcactagaaa aaggactgac
     5881 acttgcagca gctacagcaa cagttgtatt tgcaattcag aagtttattg gtacaccaat
     5941 agcttcaaga gcagcgttac aagaggcaaa ccgtctttta gtagaatatc atgaagcaaa
     6001 atcaaaaggc attgatttag caaatgttga tactgataag aaagaagcag agaatacagg
     6061 cacaaaagta aaacaagctt tctgtgaaaa atacgataaa tattattcta caaatgtttg
     6121 tatatttttt atagcactat tctcttatct agggtatgaa ctttcagaga ttattcatgt
     6181 aaattattct attgtatgtc ttgttgttgg tgttattgta acacgtattg gtattgtacc
     6241 aaaagacatt ttggaaaaag gaaaaatcaa gggatttatt aacatggttg tgtttgcagc
     6301 tgttattcct tctttagcaa aagtttcttt gacagattta attagtcttt ttgtaccaat
     6361 tgtgggtatg tttgcagctt ctatcattgg tatattcctt atgatgaagg tgttaccagg
     6421 ttggaaaatt atcggttcta aacctcttgc ttttggagta gggttttgtc agatgttggg
     6481 attcccaact acatatttaa tttcaaatga agtgtgtaat gctgttggag aaacggaaga
     6541 agaaagagca tatttgatgt ctaagattat gcctaagctg gtagttggtg gtatggcttg
     6601 tatgatttct attgtagtag ctggtcttat ggtaccaatg ttgtagatag gtttcatagt
     6661 taaaaagtgg tgttaattta taggagaagc taaaaagtag tattaattta taaaataatt
     6721 ttatattagt taatttgtta taagaatatt ttctttttat gattataatt ttgattttat
     6781 aagagagcag attttttatt tgctatgcta atagttataa tttgttttta tttgctaaaa
     6841 tgcaacttta atttgattta tgtataatat agggtattta ataatatttt tgaagaattt
     6901 ttataaaaaa ttaaaaagag gagaaaaaag ggagtgccac aaagtgaact ttttagttct
     6961 aaggcactct tttttgtacg aaatcgaata tattttcaac gttttaaaag tgagaaagag
     7021 acttatctct agtttgggat agccaaattt aattattaaa attatttttt gttttattta
     7081 tcaaagagta ttcgtgtttt agaagttagt attttttatt ttatatatcc aaggttttcc
     7141 gtttctaatg ttttcttttt taaaataatt agggtattca attatagtaa aaggtggatg
     7201 gtattttgga atgatattat ttaaagcaca gtattgaatg ttgaaatcct cacattttag
     7261 agtattatct tttgtaatca aaaaaatctt ctatacttat agcaaggtta cttctgcaaa
     7321 tattccatgc atcataatat ccaaatttaa atttttttaa tatagagttt acctctagtc
     7381 tacactcttg aataactctt tcctctatcc aaattcttat aaactcatcc catttattac
     7441 tatctattta ttactatcta aattttttag tatgtttgta attggaaatg gatttattcc
     7501 tttatgtttt ttataaatag tttataactt aatttattat taaacaaatc attcatacag
     7561 aattactttt tcttttagat attcaattct tacttttaat aaatatttaa tacattctat
     7621 cttatgtggt tttaaaaagt gtttatggct atcaataatc tctaatattt cattcatatt
     7681 tattttgtca tagtaatatt ttacatcttt tatattgaca aaaaagtgct ctaagtgtat
     7741 agtgtgtata taataacatc acactggagg tgataaaaaa tgaaagtgct catttctaac
     7801 acatcagata agccattata ccaacaaatt aaagagcaaa ttaaagaagc aatatttact
     7861 gaagaactga aagaagggga tgcaatgccc tcaataagaa attttgctaa tgatttaaaa
     7921 gttagtattt tgactattag acgagtgtat gaagaacttg aaaatgaagg ttttcttaca
     7981 cgccaagttg gaataggaac atttgtttca actggaaatt tagaaatact aagagactca
     8041 aagaggcgta tagttgaaca aaaaatggca gatatgatta aggatgcaaa agcactagga
     8101 attacacaga tagagttaca agaaatgatg ggtattctat atgaggagga ttaatatgga
     8161 aaatatttta gaagtttata acttaaataa gacttatacc aatttttcat tatctaatat
     8221 aagctttgta ttaccagaag attgtataac tggatttata ggtgttaatg gagcaggaaa
     8281 aacaacaaca attcgttcga tattggatgt cgtaaagcgt gatagtggaa aaataaaaat
     8341 ctttggtaaa gatttcgatg gaaatgagaa ggaattaaaa aatcgaattg gagttgtatt
     8401 tgatgattca tatttctatg aggagttgtc aatgtcagaa atgaaaagta ttattgcacc
     8461 ttcatatgat aattggtgtg aagaagatta tcaacaaaat atgaagcgtt ttaatcttaa
     8521 tccaaaacaa aagattgata cactttcaaa aggaatgaaa atgaaatttg ctttagcatt
     8581 agcattatcg cataaagctg agtttttaat tatggatgag cctacaagtg gtttagaccc
     8641 actaatccgt agtcagatac ttgacatact aacagaatat atgaagaaat gtggtcgtgg
     8701 tgttttcttt tctactcata taacatctga tttagacaaa atagcagata tgattgttat
     8761 gattgacaat ggacgtatta tattagagcg tgaaaaagat actctattgg atgaacatag
     8821 aaaagtaaaa ggggatattc aatttctaaa tgatgaaatc aaaaaattat ttttaaattt
     8881 agaaattaca ggttatggtt ttatagggat tacctcaaaa attaatgaag tgcaaaaaaa
     8941 tatgccagat attttaatag agcgtcctac aattgaagat attatgcttg catatattga
     9001 aaggagagag taattatgtt gattcattta gttaaaaaag atattctgat tgtaaaaaaa
     9061 tatgtattgt tgatattgtt tattgcaata ggaatcccat tatttatatt atggcgttta
     9121 cctccatttg cacaaatatt gggatttgta ctatcaatta tattttcaga atttatgctg
     9181 tgccagtatc tattattaaa ggagagtcaa tattcaaaag catctgtatt actttgttca
     9241 actccttatc ctagacgtgg cttagttcaa tctaagtatg ttttatttgc aatggtattt
     9301 atctattgta cattagttta ctggattgaa aatttactta ttccacaaat aggaactttt
     9361 gacttaacat atattttgat tgttttatta ataagttcta ttatttatgg agtttatatg
     9421 cctattcaat acaaattagg atatgaaaca acaaaattct ttttcgtgat gataatcatg
     9481 gcttcatcat ttgtattacc attaactata gctcacagca attttgaaat tccatttata
     9541 tatcagtatc catccatgat agtgaatatt gtattgttcc ttttaagttt aattatactg
     9601 ttagcttcaa tgtttatttc tattaaaatt tttagtaata aggagcttgt ataaggtaag
     9661 ggggaatttt atatgccaca tttgccagat tgggctgttt tactttgtat cttacttcca
     9721 atagtatata aagcttgtca gatatttaaa agtaaaaaat agagtacata tttatattgc
     9781 catttttatt gagtgaagtt agatggtatg aatttaaaag gttacttgaa aataaagtta
     9841 cttggtgtgg gagagtaaca tcataatatt atagattata tgtttcttgt gaatcaattt
     9901 gtatttttta atagataata tccagtaatt ttattttcca ttgattattt tcaattatga
     9961 gtatgattgt gtgtattgta taccatcttt taaggtgttt ttaaaaaatt atatcgtcaa
    10021 aatataaatc taaggaatcc tataaataaa gcttttcaat tttagaaaac taataaaaag
    10081 taggaagtta ataaaaagaa gctgtctcaa aatagagata agcttctttt tcattgctga
    10141 aatgacgaaa atataattga tttaatataa aaaagagtgc tttatgaact atttattttg
    10201 aacagtagat acacttgcac tcaatttagt tactcctaag ctttatgaac taaaagttta
    10261 ttttgaagcc tatttttcta aataatcatc tatatacagt attgcgtttc ttttatttat
    10321 tcataattta ttttcttatt aaagtttttc tatattactt tacttttaat tttatacgaa
    10381 ttatcaaaaa taaaatagtt attagaaaaa aataaaagta attgcaaaga ttgcaattac
    10441 ttacttctat attaattact ataccataaa ataacaaaaa aatcaagtcg agtaatcctt
    10501 caacttaagt gatatactag gtattaataa tttttaatta ataaaatata actagaggaa
    10561 aatctacatt ttctcaattt ctttaattaa attgacctct aattaagtaa ttataaggag
    10621 aaaaattatg aatttagcaa agggattaga tgttttaaaa atttcatcaa atgtattcgg
    10681 tgaagataaa gttatgtata ttcctgtaat ctacacagaa gatgatgcaa cacttattga
    10741 cacaggtctt ccgggtcaag gtgatttaat aattgatgct cttaataaaa gtaacacgag
    10801 ctttgatagg ttaaaaaata taataattac tcatcatgat atagaccata taggaaacat
    10861 aaattatcta agagaaaaat ctaagaataa tatcaaagta tatgcataca aaagtgaagt
    10921 cagttatata acaggagaag aaactccttt taaactttat atgttggaac aaatggtaga
    10981 taaaattgat gataagatgc ttagtatgct aaatgttatg gtacttggat ttaaatcatc
    11041 atatactaaa gtagatgtgt cattagataa ccatgaaaaa ttgaatctag gtgaggaaat
    11101 agaagttata catacaggag gtcacactag aggtcacata tgtctttatt taaaagagtc
    11161 taaagtactt attgctggag atttgttaca ggtagaaaat ggagaactta cgcctgttga
    11221 tgtaatgcac agcaacaaac aagagttaaa agatgctatt aaaaatataa gtaattatga
    11281 tatagaaacg atagttttta gtcatggtgg attatatcaa agagacataa ttggaacatt
    11341 gaaaaaccta attattgagt agtactatat gatttacaat aatttcttaa attacttaaa
    11401 attatatcta aagatgtaga atcaaaatta aatataagta ataagaattt tgctttaaaa
    11461 ttatacttaa gtgttaagta tgatacgtag tattacaagt attttagaat ataatttttt
    11521 atagtaattt taaggttcta caatacttca gttgaaaaat atttaacagc atagtataat
    11581 aggaaagaaa atattttaaa taaactttag tatacaaagt gaagaaaaat atttaaatta
    11641 tatataatat tgtagagtga ggtaaaatat ttaagttata tatcataata cagagtgaag
    11701 aaaaatattt agataatgta ccataataca aggtgagtaa aaatatttaa agcatgtata
    11761 ataatgcaaa gcgaagaaaa atatttaaat aatgtaccat aatgcagagt gagtaaaaat
    11821 atttaaataa tgtgttataa tacaaagcga ataagattat ttaaagcatg tattataata
    11881 taaagtgagt aaaaatattt aaatcatgta tcataatata agcagagtga agaaaaatat
    11941 ttaaataata tatcataatg tagagtgagg taaaatattt aagttatgta tcataataca
    12001 aagtaaagaa aatcatttaa attatatatc ataaaaataa tatgaaatat tgaacactca
    12061 taatattgga ggctttaata ttttaattga taggttacat tatttataac attaaaaata
    12121 caatttacat aaaatagaca tatgaaaaat aaaaaattat ataataatta tgggaatgag
    12181 gttctccctt ggatgataat atcctaaact gccaatgagc tgatgacttc tatgatatca
    12241 tagatgccac cagctttttt tgttgtttaa atcgataaaa tggaggtgaa ttacttacta
    12301 aatttttatt ttttaaattt gaagaaatat ttaattaata gaaaaaacag tagattatat
    12361 gttaattatt ttattaagaa tgggttaaga gtatacctat atcctatcaa tttaaaaaac
    12421 aattatgata gtcattacat tgactacagt tgatgcaata aaactttcaa aaaatcttat
    12481 gatgcaaata gaaaggaatt aaaatgatag aaaaatttaa aactttaata tggattaaaa
    12541 tgataataag aattaaaagc gtttataaaa catatggtgg actatttttg ttaggactca
    12601 taggtatacc agttggtgca attataggtc ttatagacac catatttgga acggttcttc
    12661 taaaagttac agatattcga gaaacatatc caatgtatct gataccattt ttagcagtag
    12721 taggagttgt tattgcttat tgctatttta aatttggagg aaaaagtagt aaaggaatga
    12781 atctaatatt tgaggtaggg catggagaag aagaaattat tcctttaaga ttggttccat
    12841 ttataatatc aggtacatgg ttaacccatt tatttggtgg tagtgcagga cgagaaggag
    12901 ttgctgttca gattggtgca actttttcac attgggtagg taaaaggttg cctataaaaa
    12961 atgcttctag tatttttcta gtaactggta tagcagctgg ttttgcagga ttatttgaga
    13021 caccaatagc agcaatacta tttgctatgg aggttttggt agctggttca ctggagtatc
    13081 aatcgctttt tcctgcgttt actgcttctt ttacagcaag tgcagtatca aaaactttag
    13141 ggttagagaa attttctttt gcactttctt ctaaagttgt atttgactta ccaatatttt
    13201 ggaagcttat tgttttagga attatttttg gaatggttgg tggagcattt gcatggtgcc
    13261 tgaaattgtc aaaaagaaaa ataggtaata gattaaaaaa tcctatgata aggattgcta
    13321 ttattggagt atgtcttagt gtattattcc ttttatttta taaaggaaga tattcaggtt
    13381 tagggacaaa tttaattcaa aatagttttt atggtggaga aatttattca tttgactggc
    13441 tgttaaagtt tatacttaca atactgactt tgtcagcagg ttttcaagga ggagaggtta
    13501 cacctttgtt ttccattgga gctagtcttg gtgtattgtt agcaggattt tttaatttgc
    13561 caattgaatt agttgcagcg cttggctatg ctagcgtctt tggcagtgct acaaatactt
    13621 tttttgctcc tgtatttata ggggcagaag tttttggata cagctattta ccttatttct
    13681 ttgtagtatg cgctatttca tatatattta atatggataa atctatttat tcactacaaa
    13741 aaatttcaac gaaacaataa ataaaacaac ataatgtatg attataagag aaagaatatt
    13801 agagaaagga tagggtagga atatgttgac aagtttagct ttgatttttt tattaggaat
    13861 ggcctcggga ggtatttttg agaagataaa attacctagc ttattgggaa tgttacttac
    13921 aggaatcata ttgggttcat atgttttaaa tttgattgat aattcaatac tagatatttc
    13981 ttctgacctt agaaagattg cattgattat tatattaaca agggctggat tatctttaga
    14041 tataaacgat ttgaagaaag tgggaagacc tgctgtactt atgtgcttta ttccagctac
    14101 ttttgaaatt atcggaatga tagttttagc accaaaatta ctaggcgttt ctatattgga
    14161 agcagcagtc atgggtgcag tagtaggagc agtttctccc gcaattattg tacctaaaat
    14221 gcttaaatta atggaagaag gttatggtac agaaaaaagt attccacaga tgcttttagc
    14281 aggaacttct atagacgata ttttcgtaat tgtgatgttt acagtattca caggattggc
    14341 acaaggaaat agtatatcag ctattagttt tttacaaatt ccagtatcaa ttatattagg
    14401 tgtaatagtt ggagcagtga ttggaatctg tttagcagta ttttttaaga aggttcatat
    14461 gagagattct gctaaagggg tgttgctttt aagtatctca tttttaatga taagtttgga
    14521 gactgcttta gagggtattg tgccattttc tggattatta gcagttatga atattgggat
    14581 tttccttcag ataaaatatc gtgtagttgc aagaagattg tctgtaaagt attcaaaact
    14641 atgggttggt gctgaaattc tcttgtttgt tttggtaggg gcaacagtag atataagtta
    14701 tgcatttaaa gcaggaattg gagctgtaat tttaatattt ggagttcttt tattccgtat
    14761 ggtaggagta ttcttctgcc ttattaagac aaatttgaca ataaaagaaa gattgttctg
    14821 tatgattggc tatattccaa aggctacagt acaggcagca ataggaggtg taccacttgc
    14881 aatggggata gcatctggac aacttatttt gacattagcg gttctcgcta tacttataac
    14941 tgcacctctt ggagcttttg gaattgatgt aacttataaa aaattattaa cttctgtaga
    15001 aggtaagagt aagtaagaat aaaaataaag attattttaa gtgataaatt atattttgga
    15061 aaaaactata ttattgagta caatgttaga aaatcatttg agtgattaca gaaggtagaa
    15121 gtttatatcg gattttaagg catgtgatga ttattagaat tgattttgtg aaattgttat
    15181 tgtaatattt aattatatag ataaagaagc ggagtgataa ctatgtattt aaaaaaatta
    15241 tcaaaattag agttagttat tatgaaattt atttggaatt tagatataaa aaccaattca
    15301 tatgagatta ttgattatat gaaagaagag cataatttac cagaaaaagt ggctttaaaa
    15361 attttatcaa aattatcaaa gaaaagattc ttatatgttc aagaaacagg caagtgtatg
    15421 tattatacag ttgcaataaa agaaaagaca tatttagagt ttatatcaag aaatgtgcaa
    15481 aatcttttga agaataattt tataaggaat ttattagtat catttcacga agaggagcta
    15541 acagaggaaa agataaagtc gttagaaaac tgggtagtaa attgggaaga agcttatata
    15601 taaatgttat tatttttatt acaatttaga taattttggt tttgtaagct ctgcaactat
    15661 ttttagatgg ttgcagagct tatttttatt ttttattccc ttaagcaata cttaaaagta
    15721 aacgcattta tatttactaa cttcaatcac ttctaatact tagattactt tttaaaaata
    15781 ttttgatatg tcatctctat agtaatctag aacttgtttc tattctttat ataaagtttt
    15841 tatgaatgat atatataata ttcgttcatt tgattaaaaa taacaaaata ttaaataatt
    15901 ctactctgat agtttgttaa aaaaataata aaaaatatta ataaacaaaa aaaaaaatta
    15961 tcttaagaga ggagaatgtt ctaaaatata aaaaggtttc tagatttcat aaaagatact
    16021 attttagtct tgaaaatatt tagtttgaaa agattttaat ttaatgattg attaagttaa
    16081 aaatgtgcat gtaataaatt ttattttatt tattgactaa attataaagt ttacataatt
    16141 atttaataat tatgtaattg ttacttaaaa attgatctat tttaaaatct agttataact
    16201 tcgaaaaaga ctgaaaatta agaaa
//
LOCUS       DAEQJM010000076        15959 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.077, whole genome shotgun sequence.
ACCESSION   DAEQJM010000076 DAEQJM010000000
VERSION     DAEQJM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15959
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.077"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            235..384
                     /gene="rpmG"
                     /locus_tag="KRQ43_003082"
     CDS             235..384
                     /gene="rpmG"
                     /locus_tag="KRQ43_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBH2743424.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            410..631
                     /gene="secE"
                     /locus_tag="KRQ43_003083"
     CDS             410..631
                     /gene="secE"
                     /locus_tag="KRQ43_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBH2743425.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            651..1193
                     /gene="nusG"
                     /locus_tag="KRQ43_003084"
     CDS             651..1193
                     /gene="nusG"
                     /locus_tag="KRQ43_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HBH2743426.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDVDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1229..1654
                     /gene="rplK"
                     /locus_tag="KRQ43_003085"
     CDS             1229..1654
                     /gene="rplK"
                     /locus_tag="KRQ43_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBH2743427.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1724..2422
                     /gene="rplA"
                     /locus_tag="KRQ43_003086"
     CDS             1724..2422
                     /gene="rplA"
                     /locus_tag="KRQ43_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBH2743428.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2474..2602
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2645..3151
                     /locus_tag="KRQ43_003087"
     CDS             2645..3151
                     /locus_tag="KRQ43_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBH2743429.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3209..3574
                     /gene="rplL"
                     /locus_tag="KRQ43_003088"
     CDS             3209..3574
                     /gene="rplL"
                     /locus_tag="KRQ43_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBH2743430.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3966..4754
                     /locus_tag="KRQ43_003089"
     CDS             3966..4754
                     /locus_tag="KRQ43_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH2743431.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5225..8941
                     /locus_tag="KRQ43_003090"
     CDS             5225..8941
                     /locus_tag="KRQ43_003090"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBH2743432.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGQSFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     VEATEDEDIENLEEFTEDDLFEEEIDFESDDFDM"
     gene            8983..12468
                     /gene="rpoC"
                     /locus_tag="KRQ43_003091"
     CDS             8983..12468
                     /gene="rpoC"
                     /locus_tag="KRQ43_003091"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBH2743433.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVLVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12757..13179
                     /gene="rpsL"
                     /locus_tag="KRQ43_003092"
     CDS             12757..13179
                     /gene="rpsL"
                     /locus_tag="KRQ43_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBH2743434.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13302..13772
                     /gene="rpsG"
                     /locus_tag="KRQ43_003093"
     CDS             13302..13772
                     /gene="rpsG"
                     /locus_tag="KRQ43_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBH2743435.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13821..15887
                     /gene="fusA"
                     /locus_tag="KRQ43_003094"
     CDS             13821..15887
                     /gene="fusA"
                     /locus_tag="KRQ43_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH2743436.1"
                     /translation="MARKFPLEKTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFINKMDILGADFYNVISMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6246 a         1985 c         3249 g         4479 t
ORIGIN      
        1 atggattaaa aggaataaca aaaagagggg ttaggctcct ctttttttaa catagaaata
       61 caaaaacatt gacacagcat aggattttgt gataacttat acaaggtaat gattatagga
      121 agttaataat atcttgaata ctgtagattt ttaataaata catattttaa agatattata
      181 ttcacatata ttaacaatat atattattgt attacaaagt tggaggtgta tcagatgaga
      241 gttaaagtaa ctttagcatg tacagagtgt aagcaaagaa actacaacac tactaagaat
      301 aagaaaaata atccagacag aatagaatta caaaaatatt gtagattctg taaaaagcat
      361 acaactcata aagaaacaaa atagtttttt ataaggatgt gagtatggaa tggctgccca
      421 aaaaaatgac ggtgcaaaaa ctaaaaaaag gtttagttta tttggatatt taaaagaaac
      481 taagcaagaa ttaaaaagag ttacatggcc gacaaaaaag gaactgttta aaaacacaag
      541 tatagtttta actgtagtta tttcatgcac tatattagta tggggtatag acactatatt
      601 atctggtgca ctagcgttat tactaaaata gacgaaaaga ggtaagttaa atgtcagaat
      661 tacaagaagc aagttggtat gtagttcata cctattcggg acatgaaaat aaagttaaag
      721 ctacaattga gaaagcagtt aaaacaagag gtatggaaga ctgcataaga caagtagttg
      781 ttccaacaga agaggtagtg gaaactacta aaactggaaa agaaaaaact agacaacgta
      841 aagtttatcc aagttatgtc ttggttaaaa tgataataac tgatgaatct tggtatgtag
      901 taagaaatac taagggagtt acaggtttcg ttggacctgg ttcaaaacca gtaccattaa
      961 gtgaagatga agtcaaagct atggggatag atacaacaga ccctaaagta gtaaatagcg
     1021 atgttgattt tgaaatagga gacacagtaa aagtatctca aggaccattt agtggacaaa
     1081 taggtaacat agaagaaatt gacttagaaa atagagaagt caaagtatgc ataaatgcat
     1141 ttggtaaaag gactctattt gtaatagagc ttgaaggtat agaaaaaatc taatactata
     1201 tagaaaaatc tgaggaggtg cgctcaaaat ggctaaaaaa gttataggtc aaataaaatt
     1261 acaaatacct gcaggaaagg ctactccagc gccaccagtt ggaccagcat taggacaaca
     1321 tggtgttaat ataatgggat tcacaaaaga atttaatgct aaaactgcag atcaagctgg
     1381 aatgataata ccagttgtta taactgtata tcaagataga tcattcagtt ttataacaaa
     1441 aactccacca gctgcagttt taattaaaaa agcattaaac ttaaaatcag gttctggaga
     1501 accaaacaaa aagaaagttg ctaaaatgac ttcagctcaa gtaagagaaa tagctgagtt
     1561 aaaaatgcct gacttaaatg ctgcatcagt agaagctgct atgagtatga tagctggtac
     1621 tgctagaagc atgggtgttg taatcgaaga ctaattaaaa gatacacttt ttttataaag
     1681 tgggaggcga gaagccgaaa ttaaccacaa ggaggaaaat aaaatggcta aaaaaggtaa
     1741 aagatatgca ggtgcattac aaaaagtaga tagaactaaa ttttatgatg catcagaagc
     1801 attaacatta gtttcagata tagctggagc taaatttgat gagacagtag aagcacacat
     1861 taaattaggt gttgactcaa gacatgctga ccaacaagta agaggtgcag ttgtattacc
     1921 tcatggaact ggtaaaacaa aaagagtttt agtttttgct aaaggtgaaa aagctaaaga
     1981 agctgaacaa gctggtgctg actttgtagg agctgaagaa ttagttcaaa aaatacaagg
     2041 tgaaaactgg tttgactttg atatagtagt tgctactcca gatatgatgg gtgtagtagg
     2101 tagattaggt agagtattag gacctaaagg tttaatgcca aaccctaaat caggaacagt
     2161 tacatttgat gtagctaaag ctatagatga aataaaagct ggtaaagttg aatacagatt
     2221 agacaaaact aacataatac acgttccagt aggaaaagta tcatttggtg gagaaaaatt
     2281 aactgaaaac tttactgcat taatggatgc tataataaaa gctaaaccag ctgctgctaa
     2341 aggacaatat ttaagaagta taacagtagc ttcttcaatg ggacctggag ttaaaataaa
     2401 cccagcaaga acagctgaat aataaaactg ttgacacagg ttgacaaaaa tgttattata
     2461 tcacttgtca atgtaaaaaa gaatagattt gccgtagata gtgggtgcga aagcttaata
     2521 tcccgccgag gttttagata aattgagatt actaaagctt ttgatgtcta cttttggcaa
     2581 caaaagcttt ttataatgtt gcggtaaata ttaagcctat ttggtgaagg aggtgcacat
     2641 ctatatgaga aaagctatag aaattaaatc agaagttgtt tctgagatag ttgaaaagtt
     2701 acaaaaatct tctgctgctg ttgttgtaga ttacaaagga ttaacagttg aagaagtaac
     2761 tgagttaaga aaacaaatga gagaagctgg tgtagattac aaagtataca aaaatacttt
     2821 agttagaaga gcagctaaag aagttggtat agagcaattt aatgatgaat tattagttgg
     2881 aactaatgcc atagcatttg gatatgatga tccagttgct ccagctagaa tattaaaagg
     2941 attcatggat tctcatccaa aaatgaaatt aaagatgggt attgtggaag gtgcattcta
     3001 tgatgaatct aagattgttg aaatggctaa cataccatca agagaagttc ttatcgctaa
     3061 attacttggt agcttaaaag ctccagtatc aaacttcgca tacttaatag atgcaatagc
     3121 gaaaaaggca gaaggtcaag aagaagctta attgcttaac taaaaaatta taaatattaa
     3181 tttgaaataa aattcggagg tgctaaaaat gacaatagaa caaatattag aagctataga
     3241 aaatatgaaa gttttagaat taaatgaatt agttaaagct gctgaagaaa aattcggtgt
     3301 atcagcttca gctccagtaa tggtagctgg tgcagctgct ggtggaccag ctgctgaaga
     3361 aaaaactgag tttgatgtag tattaactga cgttggttct tcaaaagttg gagttataaa
     3421 agcagttaga gaaataacag gattaggatt aaaagaagct aaagaagtag ttgacaatgc
     3481 tcctaagaca gttaaagaag gagcttctaa agaagaagct gatcaaataa aagagaaatt
     3541 agaagctgct ggagctaaag tagaagttaa gtagtttctt taaaaagata cccattgggt
     3601 atcttttttt atttataaaa aactataaag aaagtatttg gaattataaa gaaagtgttt
     3661 ttataaaata aaaaaaattt atataatagt actaaattaa gggtatcata tatggtgtaa
     3721 tggtatttta atttaacatt attatcaaat taaaatataa acaattgttg taatgtctgt
     3781 atataaagta tataattaaa ctaaaatgta aaattttaca ttttagttta aaaaaataca
     3841 cgagtgtttt ataaataaaa tgtaataaat aattaattaa caaatataaa ttttaaaata
     3901 agttagatat ttagaaaaat cgaaatttgt aggatttaaa ggacatattc aaggaggagt
     3961 taataatgga aaaattacaa ggaaaaattg cagtagttac tgcagcaaca aaaggtattg
     4021 gattagcatc agcagagata ttagcaaaaa atggagcaac tgtgtactta gcagctcgtt
     4081 cagaagaatt agctaatgaa gttataaata aaataagtgc agaaggtggt tgtgctaagt
     4141 ttgtttactt taatgctcgt gaagaagaga cctttacctc aatgatagaa gaggtagtta
     4201 aaaaagaagg taagatagat atacttgtaa acaattttgg ttcaacaaac ccttctcttg
     4261 acaaagacct tgtaactggg gatacagata atttctttga cacagtaaat actaatttaa
     4321 aaagtgtgta tttaccatgt aaagcagcaa ttcctcatat gataaagaat ggaaaaggaa
     4381 gtatagtaaa tatatcaagt ataggttcag tattacctga tttatctaga atagcttact
     4441 gtgtatcaaa agcagcaatc aactcattaa ctcaaaacat agctacacaa tatgctaaag
     4501 acaatgttag atgtaatgct gtacttccag ggcttattgc aactaaagca gcattagaca
     4561 atatgtctcc agagttcata aaagaatttt taaagcatgt tcctttaaat cgtatagggg
     4621 aaccagatga tatagcaaaa gctgttctat tctatgctag tgatgactca tcatttataa
     4681 caggggattt acttgaagtt gcaggaggat ttggtttacc tactccacaa tttgcagata
     4741 atatattagg ataattaaat tactaatatg caatgaaagc ttatgcatta gttatagtag
     4801 aaatgatatt tttataaagg ccatagatat aatttatatt ggaaaggttt gaggttcaaa
     4861 attccaagtt aaatttattt atggtcttta ttttgtatat tttaataaat tgtatatatt
     4921 tgtataaatg taattattta caatcatttt aatatggaat tataattaaa taggggggat
     4981 ggtacttgta taaaattttt tatagaaaat tagacctata aatgaaaaat atggatttta
     5041 tattggaaaa ttgtacataa tacataatat atgcttaaaa taatttacaa aaaatcaaaa
     5101 ataatgcata gtttacatat aagataaaaa atatattgaa aaatacttga cattatgcta
     5161 aaattattag atgcgttaga atgaactatt gttttatttt taattattga gaggtgaaaa
     5221 gtgaatgcca catcctgtca cgataggtaa aagaactaga atgagctttt ctaaaattaa
     5281 ggaaatagct gatgtgccaa atcttataga aattcaagta gattcctatg agtggttttt
     5341 aaaagaaggt ttaaaagaag tgtttgatga tatttcacca atagaagatt atactggtaa
     5401 tcttatattg gaatttgtcg actattctct agatgataaa ccaaagtacg atatagaaga
     5461 gtgtaaagag agagatgcta catattgtgc acctctaaag gttaaggtaa gacttataaa
     5521 taaagaaaca ggtgagataa aagaacaaga agtgtttatg ggtgacttcc ctttaatgac
     5581 agaaagagga actttcgtta taaatggagc agaaagagtt atagtaagtc aattagttag
     5641 atctcctggt gtttactatg cggaagaaag agataaaaca ggtaagagat tgatttcatc
     5701 tactgtaatt cctaatagag gagcatggtt agaatatgaa acagattcta atgatgtaat
     5761 atctgtaaga gttgatagaa caagaaaaca accagttaca gttttactta gagctttagg
     5821 aataggaaca gatgcagaga taattgacct tttaggagaa gatgagagat tatctgctac
     5881 attagaaaaa gataatacta agacagtaga agaaggtctt gtagagatat acaaaaaatt
     5941 aagaccaggt gaacctccta ctgtagaaag tgcatcatct ttattaaatg ctttattctt
     6001 tgacccaaaa agatatgacc tagcaaaagt tggtagatat aaattcaata agaaacttgc
     6061 tttatgttat agaataatga ataaaatttc agcagaagac ataataaatc cagaaactgg
     6121 agaagtattt gtaaaagctg gagaaaaaat aagctatgat ttggctaaag ccatacaaaa
     6181 tgcaggtata aatgtagtaa atctactaat ggatgatgat aaaaaagtta gagttatagg
     6241 aaataatttt gtggatatta agtctcacat tgattttgac atagatgatt taaacataaa
     6301 agaaaaagta cattatccaa ctttaaaaga aattttagat ggatatagtg atgaagaaga
     6361 aataaaagag gctataaaat caagaattaa agaacttata ccaaaacata tattattaga
     6421 tgatataata gcttcaataa gttatgagtt caatatattc tataatatag gaaatattga
     6481 tgatatagat cacctaggaa acagaagaat aagatctgta ggtgaattgt tacaaaatca
     6541 agttagaatt ggtctttcaa gaatggaaag agttataaaa gaaagaatga cggttcaaga
     6601 tatggaagct ataacgcctc aagcgttagt taacataaga ccagtttcag ctgcaataaa
     6661 agaatttttt ggtagttctc agttatctca gttcatggat caaacaaatc ctctatctga
     6721 gttaacgcat aagagaagat tatcagccct tgggcctgga ggtctttcaa gagaaagagc
     6781 tggattcgaa gtgcgtgacg ttcaccattc acactatggt agaatgtgtc caatagagac
     6841 tccagaggga ccaaatatcg gtcttataaa ctctctagga acttatgcaa aaataaatga
     6901 atttggattt atagaatcac catatagaaa atttgataaa gaaacatcaa cagttactga
     6961 tgaaatacat tatttaactg ctgacgaaga agatttattc gtaagagctc aggcaaatga
     7021 gccattaaca gaagatggta aattcgtaaa ccatagagtt gtttgtagaa ctgtaaatgg
     7081 tgctgttgaa atggttcctg aaagtagagt agattacatg gatatatctc ctaagcaggt
     7141 tgtatctgtt gccactgcta tgataccttt cttagaaaat gatgatgcca accgtgccct
     7201 tatgggagcg aacatgcagc gtcaggcagt gcctctagtt agaagagaag caccaattat
     7261 aggaactggt atagaataca gagcagcaaa agactctgga gcagttgttg ttgctagaaa
     7321 ttctggtata gcagaaagag taacagcaga tgaaataatt ataaaaagag aagatggaaa
     7381 cagagataga tataatctac ttaagtttaa acgttcaaac tcaggtactt gtataaatca
     7441 aacacctata ataaataagg gtgaccagat aataaaaggt gatgttatag cagatggtcc
     7501 agcaactgat ttaggagaag ttgcacttgg aagaaactgt cttatagcat tcatgacttg
     7561 ggaaggttat aactacgagg atgctatatt aataaatgaa agattagtta aagaagatag
     7621 attatcaaca attcatatag aagaatatga atgtgaagct agagatacaa aactagggcc
     7681 agaggaaata actagagata tacctaatgt tggagatagt gcaatcaaaa acttagatga
     7741 tagaggtata ataagaatag gtgcagaagt agactcaggt gatatattag ttggtaaggt
     7801 aactccaaaa ggagaaactg aacttactgc tgaggaaaga ttacttcgtg cgatattcgg
     7861 agaaaaagcc agggaagtta gagatacttc acttaaagta cctcatggtg aatctggtat
     7921 aatagttgat gtaaaagtat ttactagaga aaatggagat gatttatctc caggagtaaa
     7981 tgaattagta agatgttata tagctaaaaa gagaaagata aaagttggag ataagatggc
     8041 tggtcgtcat ggtaataaag gggttatctc gagagtatta cctgaagaag atatgccatt
     8101 catggaaaat ggaacgccat tagatataat acttaaccca caaggtatac catcacgtat
     8161 gaacatcggt caggttctag aagttcattt aggacttgct gctaagacat taggatggta
     8221 tgtagcaaca tcagtattcg atggtgctaa tgagtatgac ataatggatg ctcttgaaga
     8281 agctggatat cctagagatg gtaaattaac tttatatgat ggtagaacag gtcaatcttt
     8341 tgacaataga ataactgttg gatatatgta ttacttgaaa ctacatcact tagtagatga
     8401 aaaactacat gcaagaagta ctggaccata ctcattagtt actcaacagc cactaggtgg
     8461 taaagcacaa tttggtggac aaagatttgg agagatggag gtttgggctc tagaagcata
     8521 tggagcggct cacatacttc aagagatact tactgttaag tctgatgatg ttgtaggtcg
     8581 tgttagaact tatgaagcta tagttaaagg tgaaaacata cctgagccag gaatcccaga
     8641 atcatttaag gttcttataa aggaacttca aagtttatgc ttagatgtaa aagtattgac
     8701 agatgaagac caagaaatag aagtaagaga atctgtagat gaagatgata cgataggtga
     8761 atttgagcta gacgttgtaa atcacatggg agaagttgaa gaaagtaata taatagaaga
     8821 aattgaagat gattttgtgg aagccacaga agatgaggat atagagaatt tagaagaatt
     8881 cactgaagat gatttatttg aagaagaaat agattttgaa agtgatgact ttgatatgta
     8941 aatttaatta atgtaaatct caaatagaag ggagagaact ccttgtttga attaaacaat
     9001 ttcgagtcga taaaaatagc attggcttct ccagaaaaaa taagacaatg gtctagagga
     9061 gaagttaaaa agccagaaac tataaattac cgtactttaa agccagaaaa agatggtctt
     9121 ttctgtgaaa ggatatttgg accacaaaaa gactgggagt gtcattgtgg taaatataga
     9181 agagttagat ataaaggtgt agtttgtgat agatgtggag tagaagtaac taaatcaaaa
     9241 gtaagaagag agagaatggg acatatagag ctagctgctc ctatgtctca catctggtac
     9301 ttcaaaggta taccaagtag aatgggactt ttacttgata tgtcaccaag atcgttagaa
     9361 aaaatactat atttcgcctc atatgtagta gttgatccag gtgaaactgg attgaatgaa
     9421 aaacagttac ttacagaaaa agaatacaga actgctcttg aaaagtatgg atatactttt
     9481 actgtgggta tgggtgctga agctgtaaaa acattactac aaaatataga tttagaacaa
     9541 caaagtaaag acttaagagc ggaattaaaa gatagtacag gacaaaagaa agtaagaaca
     9601 attagaagat tagaagttgt agaagcattt aaaaaatctg gaaataaacc agaatggatg
     9661 attttagatg caataccagt aataccgcca gatttaagac caatggtaca acttgatggt
     9721 ggaagatttg caacttcaga cctaaatgat ttatacagaa gagttataaa tagaaataat
     9781 agacttaaaa gactattaga gcttggagct ccagatataa ttgtaagaaa tgaaaaaaga
     9841 atgcttcaag aagctgttga tgcattgata gataatggta gaagaggtag acctgtaaca
     9901 ggacctggaa atagaccact taaatcttta tcagatatgt taaaaggtaa gcaaggtcgt
     9961 ttccgtcaaa acttacttgg taagcgtgtt gactactcag gacgttctgt tatagttgtt
    10021 ggaccagaac ttaaatttta tcaatgtgga cttccaaaga agatggcatt agaattattc
    10081 aagccatttg ttatggataa attagttaaa gaaggttatg cacataatat aaaaagtgcg
    10141 aaatctatag tagaaaaagt taagccagaa gtttgggatg ttttagaaga tgttataaaa
    10201 agtcatccag ttcttcttaa ccgtgcaccg actctacata gattaggtat acaagcattt
    10261 gaaccaatct tagttgaagg taaggctata aaactacatc ctcttgtatg tacagcttat
    10321 aatgcagact ttgatggtga ccaaatggca gtccatgtac ctttatcagt agaagcacaa
    10381 gcagaagcaa gattcttaat gctttctgta aataatatac ttgctcctaa agatggttca
    10441 cctataacta ctccatctca ggatatggtt ttaggttgct attatctaac aatagaagcc
    10501 caagatggag ctaaaggaac aggtatggta tttaaagact ttaatgaact attacttgct
    10561 tattacaata aatcagttca tctacatgca ttagtgaaac tgaaggtaac acttgaagat
    10621 ggaagaagtt cattggttga aagtactgtt ggtagattta tatttaatga aaatatacct
    10681 caagacttag gttttgtaga tagaaaagaa aatccatttg cacttgaagt tgatttctta
    10741 gcagataaaa aatctcttgg taaaataata gataaatgct ttagaaaaca cggaaataca
    10801 gaaacagctg aattactaga ttatataaaa gctctaggat ttaaatattc tacattaggt
    10861 ggtataacag ttgctgttga tgatatgagt gtcccagaag aaaagaaagt atttatagct
    10921 gaggcagaag ctaaagttga taagtatgaa aaagcataca gaagaggtct aatctctgat
    10981 gaagaaagat atgaaaaagt tatagagaca tggacagaaa caactgataa agttactgat
    11041 gctcttatgg gtggactaga tagattaaat aatatatata taatggcaca ttcaggagcc
    11101 agaggttcta aaaaccaaat tagacagctg gcaggtatgc gtggtcttat ggcaaatgca
    11161 tctggtaaaa cagtcgagat accagttaaa tctaatttcc gtgaaggttt atcagtacta
    11221 gaatacttta catcttcaca tggtgccaga aaaggtcttg ccgatacagc tatacgtaca
    11281 gctgaatctg gatatttaac aagaagactt gttgatgtaa gtcaagatgt tattgtaagg
    11341 gaaatagatt gtggaacaga agatactaca gagatttatg ctataaaaga aggaaatgaa
    11401 gttatagaag agatatatga tagaattgta ggaagatata ctatagaccc tatattaaat
    11461 cctgaaactg gagaagttct agttgaggct gattcaatga tacaagaaga tgaagcagaa
    11521 actatagtag ctttagggat tgaaaaaatt aggataagaa cagttcttaa ctgtaaaact
    11581 aatcatggag tttgttctaa gtgttatggt agaaacttgg caacaggaaa agaagttaat
    11641 ataggtgaag cagttggtat aatagcagct caatctatcg gtgagccggg tactcagctt
    11701 acaatgcgta cattccatac tggaggagtt gcaggagctg atataactca aggtctacca
    11761 agggttgaag aattatttga agctagaaaa ccaaaaggat tagctgtaat aactgaagta
    11821 tctggtagag ttgaaattga tgaaacagga aagagaaaag aagtaaatgt aataccagaa
    11881 gaaggcgaga ctcaaacata tgtaattcca tatggttcta gattaaaagt taagcaaggt
    11941 caaatgctag aggctggaga ccctctaaca caaggattta taaatcctca tgatatagta
    12001 agagtaaatg gtgttaaggg agttcaagaa tatatagtta aagaagttca aagagtgtat
    12061 agacttcaag gggttgatgt taatgataag catatagaag ttatagtaag acaaatgcta
    12121 tctaaagtaa aagttgaaga cccaggagat acagatttat tgccaggtgg atatgaagat
    12181 gtattaacat tcaatgaatg taataaagat gctatagata aaggtctaag accagcagtt
    12241 gctaaaagag ttttacttgg tataactaaa gcatctcttg caactgattc attcttatca
    12301 gcagcttctt tccaagaaac aacaagagta ttaacagagg cagcaataaa aggtaaagaa
    12361 gaccacttaa taggacttaa agaaaatgtt atattaggta agttaatacc agcaggaaca
    12421 ggaatgaaga aatatagaaa tatagctgtt gaaaaaattg aagattaata gcatatagag
    12481 taaagaaatc ttgacaacca ttatttgtgg tgttaaaata gtaaagtgtg ttgtttaaaa
    12541 gtacactaag ggcttgaaca agttcttagt gacttttaga tggcaataaa tgagaactaa
    12601 aaagcatcaa gctagaaaag tgctaatatc acatatttat gtgttataga cattaaattg
    12661 taagtaacga atgttacaat cagtcagtat gaatattcat attgatgtag ttggcggtca
    12721 ctgataagat cgaaaatttg gaaggaggtg cagatgatgc caacaattaa ccaattagtt
    12781 cgtaaaagta gaaaagcgct agagaagaaa tctactgctc cagcattaca aaaaggttac
    12841 aactctttaa ataagaaagt aactgacgct agtgccccac aaaaaagagg ggtttgtact
    12901 tcagtaaaaa cagttactcc taagaagcct aactcagctt taagaaaagt tgccagagtt
    12961 agattaacta atggtataga agtttctgct tatataccag gagaaggaca caacttacaa
    13021 gagcatagtg ttgttcttat aagaggagga agagtaaaag accttccagg ggttagatac
    13081 catatactaa gaggtactct agatacagca ggtgttgata agagaagaca atcaagatct
    13141 aaatacggtg cgaagagacc taaagaagct aaaaaataaa acaattaatg attgattata
    13201 gttcggtgct ttaaatatat atatatttac ggcatcacgg cattaaatga tttatgtcga
    13261 gtacctatga tttaagttaa ataattaagg agggaagcga aatgccaaga aaaggtaata
    13321 ttccaaaaag agaagtttta ccagatccta tgtatgggag taaggtagtt actaaattaa
    13381 taaataatct aatggtagac ggaaaaaaag gaaagtctca aagaatagtt tatgatgctt
    13441 tcgcaattgt tgctgaaaag acaggagaag aagctttaga agtatttaat aaagcaatgg
    13501 ataatataat gcctgtttta gaagtaaaag caagaagagt tggtggggca aattaccaag
    13561 tgccaatcga agttagacct gaaagaagac aaacattagg tttaagatgg ctagtaaaat
    13621 atactagagc tcgtggagaa aaaggaatgg ttgaaaagct agctaaagag ataatggacg
    13681 cagctaacaa cactggagct tcagttaaga aaaaagaaga tactcataaa atggcagaag
    13741 ctaataaagc atttgctcat tacagatggt aggatatata gatatcttat aaattcaagg
    13801 atatcataag gaggataacc atggctagaa agtttccttt ggaaaaaact aggaatatag
    13861 gaatcatggc tcatatagat gcaggaaaga ctactactac agaaagaatc ctgttttata
    13921 ctgggcaaac tcataaaata ggagaaactc atgaaggagc ttctcaaatg gactggatgg
    13981 agcaagaaaa ggaaagaggt ataacaataa cttctgccgc tactactgct tcatggaaag
    14041 accatagaat aaacataata gatactcctg gacacgtgga cttcacagtt gaggttgaaa
    14101 gatctctaag agttcttgat ggttcagttg ctgtattctg tgcaaaaggt ggggttgagc
    14161 ctcaatctga aaatgtatgg agacaagctg aaacttatgg agtacctaga atagctttta
    14221 taaacaaaat ggatatatta ggtgcagatt tctacaatgt tataagcatg atgaaatcta
    14281 gattaaattc taatgcagtt cctatgcaat taccaatagg taaagaagat tcatttatag
    14341 gtataataga cttattaaaa atggatgctg ttatatacaa agacgaccta ggggttgaaa
    14401 tggaagaaac agatatacca gaagatatga aagaattagc tgctgagtgg agagaaaaat
    14461 tagttgaatc agtagctgaa actgatgaag aattaatgat gaaatacctt gaaggtgaag
    14521 aacttactat agatgaatta aaagttgcta taagaaaagc tactatagct tgtgaaatga
    14581 acccagtttt ctgtggtaca gcttatagaa acaaaggtgt tcagttagta atagatgcag
    14641 ttttagatta cttaccagca ccaactgata taccagctat aaaaggtata ttagcagatg
    14701 gagaagaagc tgaaagacat tcttctgatg aagagccatt ctctgcatta gcattcaaaa
    14761 taatgactga cccattcgtt ggaaaactag cgttcttcag agtttattct ggaacattag
    14821 aatcaggttc ttatgtttta aatgcaacta agaataagag agaaagaatt ggtcgtatat
    14881 tacaaatgca tgctaataca agagaagaaa taactaaagt gtatgctgga gatatagcag
    14941 cagcagtagg attaaaagat actactactg gagacacatt atgtgaccct gctaatccaa
    15001 taatacttga atctatggaa ttccctgagc cagttatatc tgttgctata gaaccaagtt
    15061 ctaaagcagc tcaagaaaaa atgggtatag ctcttcaaaa attagctgaa gaagacccaa
    15121 ctttcacagt taagactgac caagaaacag gacaaactat aatatctggt atgggtgaat
    15181 tacacttaga gataatagta gatagattat taagagaatt taaagtagaa gctaaagttg
    15241 gtgcaccaca agttgcatat agagagacta taactcaacc agttgatgtt gaatacaagt
    15301 actctaagca atcaggtggt agaggacaat acggtcacgt taagattaga gttgctcctc
    15361 aagagccagg tgaaggatac aagttcacaa acaaaactgt tggtggatca gtaccaaaag
    15421 aatatgttgg tccagttgac atgggtatac aaggagctat gcaatctggt atagttgctg
    15481 gatatccagt tgtagacgtt gctgttgagt tatatgatgg ttcttaccat gaggttgact
    15541 cttctgagat ggcgtttaag atggctggtt caatggcatt caaagatgct atgaagaaag
    15601 gtaatgcagt tcttttagag ccttacttca aagtagaagt tgttactcca gaagattaca
    15661 tgggagatgt tatgggtgac ttaaactcaa gaagaggatt aatccaaggt atggaagcta
    15721 gaagtggtgc acaagttata aatgcattcg ttccactttc agaaatgttt ggatactcaa
    15781 cagacctaag atcttcaact caaggtcgtg caacttacac aatgatattc gatcactatg
    15841 agcaagttcc agcttcagtt gctaagaaaa tagctgaagg aaaataattt aaaaataatt
    15901 aataatataa atataaaaaa taatcagcta gatgagatat atctcatcta gcacaagat
//
LOCUS       DAEQJM010000077        15946 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.078, whole genome shotgun sequence.
ACCESSION   DAEQJM010000077 DAEQJM010000000
VERSION     DAEQJM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15946
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.078"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            111..665
                     /gene="tcdR"
                     /locus_tag="KRQ43_003095"
     CDS             111..665
                     /gene="tcdR"
                     /locus_tag="KRQ43_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HBH2743437.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            996..8096
                     /gene="tcdB"
                     /locus_tag="KRQ43_003096"
                     /gene_synonym="toxB"
     CDS             996..8096
                     /gene="tcdB"
                     /locus_tag="KRQ43_003096"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HBH2743438.1"
                     /translation="MSLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIVESATNDTLESFREN
                     LNDPRFDYNKFYRKRMEIIYDKQKNFINYYKTQREENPDLIIDDIVKIYLSNEYSKDI
                     DELNSYIEESLNKVTENSGNDVRNFEEFKGGESFKLYEQELVERWNLAAASDILRISA
                     LKEVGGVYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMVKLEAIMKYKEYIPGYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNAFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKKNYFEGSLGEDDNLDFSQNTVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGLDVDSLSTEIETAIDLA
                     KEDISPKSIEINLLGCNMFSYSVNVEETYPGKLLLRVKDKVSELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKIIVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLAECEINVISNIDTQVVEGRIEEAKSLTSDSINYIK
                     NEFKLIESISDALYDLKQQNELEESHFISFEDILETDEGFSIRFIDKETGESIFVETE
                     KAIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDATHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     VIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTAATTAIITSSLGIASG
                     FSILLVPLAGISAGIPSLVNNELILRDKATKVVDYFSHISLAESEGAFTSLDDKIMMP
                     QDDLVISEIDFNNNSITLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPVITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMNINIELNENDTWVIDVDNVVRDVTIESDKIKKGDLIENILSKLSIE
                     DNKIILDNHEINFSGTLNGGNGFVSLTFSILEGINAVIEVDLLSKSYKVLISGELKTL
                     MANSNSVQQKIDYIGLNSELQKNIPYSFMDDKGKENGFINCSTKEGLFVSELSDVVLI
                     SKVYMDNSKPLFGYCSNDLKDVKVITKDDVIILTGYYLKDDIKISLSFTIQDENTIKL
                     NGVYLDENGVAEILKFMNKKGSTNTSDSLMSFLESMNIKSIFINSLQSNTKLILDTNF
                     IISGTTSIGQFEFICDKDNNIQPYFIKFNTLETKYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVIISPNIYTDEINITPIYEANNTYPEVIVLDTNYIS
                     EKINININDLSIRYVWSNDGSDFILMSTDEENKVSQVKIRFTNVFKGNTISDKISFNF
                     SDKQDVSINKVISTFTPSYYVEGLLNYDLGLISLYNEKFYINNFGMMVSGLVYINDSL
                     YYFKPPIKNLITGFTTIGDDKYYFNPDNGGAASVGETIIDGKNYYFSQNGVLQTGVFS
                     TEDGFKYFAPADTLDENLEGEAIDFTGKLTIDENVYYFGDNYRAAIEWQTLDDEVYYF
                     STDTGRAFKGLNQIGDDKFYFNSDGIMQKGFVNINDKTFYFDDSGVMKSGYTEIDGKY
                     FYFAENGEMQIGVFNTADGFKYFAHHDEDLGNEEGEALSYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGISIINDGKYYFNDSGIMQIGFVTINNEVFYFS
                     DSGIVESGMQNIDDNYFYIDENGLVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFDPETKKAYKGINVIDDIKYYFDEN
                     GIMRTGLITFEDNHYYFNEDGIMQYGYLNIEDKTFYFSEDGIMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8218..8718
                     /gene="tcdE"
                     /locus_tag="KRQ43_003097"
     CDS             8218..8718
                     /gene="tcdE"
                     /locus_tag="KRQ43_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HBH2743439.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAVLLDAMTDEM
                     NAKDEK"
     gene            9047..9229
                     /locus_tag="KRQ43_003098"
     CDS             9047..9229
                     /locus_tag="KRQ43_003098"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743440.1"
                     /translation="MRDEGQNDRENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9446..>15946
                     /gene="tcdA"
                     /locus_tag="KRQ43_003099"
                     /gene_synonym="toxA"
     CDS             9446..>15946
                     /gene="tcdA"
                     /locus_tag="KRQ43_003099"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021394011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HBH2743441.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKNSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     LLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTIPRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKDSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKEYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPYISSHIPSLSV
                     YSAIGIKTENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENNGTKLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNTKIKLDKDTRNFIMPTITTDEIRNKLSYSFDGA
                     GGTYSLLLSSYPISMNINLSKDDLWIFNIDNEVREISIENGTIKKGNLIEDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNGSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLNNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIESNLVTGWQTINGKKYYFDINTGAASTSYKIINGKHFYFNNNGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSGSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTSIASTGYTIINGKYFYFNTDGIMQIGVFKVP"
BASE COUNT         6438 a         1697 c         2509 g         5302 t
ORIGIN      
        1 ataaaattta atttatttgc cgattatata attataatga ctgatttaat tccaatgttg
       61 tcaaaatttt taaataaatc atcattataa atataagaga ggatgatttt atgcaaaagt
      121 ctttttatga attaattgtt ttagcaagaa ataactcagt agatgatttg caagaaattt
      181 tatttatgtt taagccatta gtaaaaaaac ttagtagagt tttacattat gaagagggag
      241 aaacagattt aataatattt tttattgaat taataaaaaa tattaaatta agtagctttt
      301 cagaaaaaag cgatgctatt atagtcaaat atattcataa atcattactg aataagactt
      361 ttgagttgtc tagaagatat tctaaaatga agtttaattt tgtagaattt gatgaaaata
      421 tcttaaatat gaaaaataat tatcaaagta agtctgtttt tgaggaagat atttgttttt
      481 tcgaatatat tttgaaagaa ttatctggta ttcaaagaaa agttattttt tataaatatt
      541 taaaaggata ttctgataga gaaatatcag tgaaattaaa aatatctaga caagctgtta
      601 ataaggctaa aaatagagca tttaaaaaaa taaaaaaaga ctatgaaaat tattttaact
      661 tgtaattaat gaatttaaag aaatatttac aatagaaatc aaattttaga attaacttta
      721 ttgtaaaatc aataacttaa tctaagaata tcttaatttt tatattttat atagaacaaa
      781 gtttacatat ttatttcaga caacgtcttt attcaatcga agagcaaatt aatcaactga
      841 gtgtcttcaa tttaaaatgt taggaagtga atgtatatga aaacctaagt agatattagt
      901 atattttata aatagaaagg aggatatata aaagagtttt agcatttaga tgtaaaaata
      961 ttcaataaaa atattatagt aaaggagaaa attttatgag tttagttaat agaaaacagt
     1021 tagaaaaaat ggcaaatgta agatttcgtg ttcaggaaga tgaatatgta gcaatattgg
     1081 atgctttaga agaatatcat aatatgtcag agaatactgt agtcgaaaaa tatttaaaat
     1141 taaaagatat aaatagttta acagatattt atatagatac atataaaaag tctggtagaa
     1201 ataaagcctt aaaaaaattt aaggaatacc tagttacaga agtattagag ctaaagaata
     1261 ataatttaac tccagttgag aaaaatttac attttgtttg gattggaggt caaataaatg
     1321 acactgctat taattatata aatcaatgga aagatgtaaa tagtgattat aatgttaatg
     1381 ttttttatga tagtaatgca tttttgataa acacattgaa aaaaactata gtagaatcag
     1441 caacaaatga tacacttgaa tcatttagag aaaacttaaa tgaccctaga tttgactata
     1501 ataaatttta cagaaaacgt atggagataa tctatgataa gcagaaaaat ttcataaatt
     1561 actataaaac tcaaagagaa gaaaatcctg accttataat tgatgatatt gtaaagatat
     1621 atctttcaaa cgagtattca aaggatatag atgaacttaa ttcctatatt gaagagtcat
     1681 taaataaagt tacagaaaat agtgggaatg atgttagaaa ctttgaagaa tttaaaggtg
     1741 gagagtcatt caaattatat gaacaagagt tggtagaaag atggaatttg gcagctgctt
     1801 ctgacatatt aagaatatct gccttaaaag aagttggtgg tgtatattta gatgttgata
     1861 tgttaccagg aatacaacca gacctatttg agtctataga gaaacctagt tcagtaacag
     1921 tggatttttg ggaaatggta aaattagaag ctataatgaa atacaaagaa tacataccag
     1981 gatatacttc agagcatttt gatatgttgg atgaagaagt tcaaagtagt tttgaatctg
     2041 ttctagcttc taagtcagat aagtcagaaa tattctcatc acttggcgat atggaggcat
     2101 caccactaga agttaaaatt gcatttaata gtaaaggtat tataaatcaa ggactaattt
     2161 ctgtgaaaga ctcatattgt agcaatttaa tagtaaaaca aatcgagaac agatataaga
     2221 tattgaataa tagtttaaat ccagctatta gcgaggataa cgatttcaat actacaacga
     2281 atgcttttat tgatagtata atggctgaag ctaatgcaga taatggtaga tttatgatgg
     2341 aactaggaaa gtatttaaga gttggtttct tcccagatgt taaaactact attaacttaa
     2401 gtggccctga agcatatgcg gcagcttatc aagatttatt aatgtttaaa gaaggtagta
     2461 tgaatatcca tttgatagaa gctgacttaa gaaactttga aatctctaaa actaatattt
     2521 ctcaatcaac tgaacaagaa atggctagct tatggtcatt tgacgatgca agagctaaag
     2581 ctcaatttga agaatacaaa aaaaattact ttgaaggttc tcttggagaa gatgacaatc
     2641 ttgacttttc tcaaaataca gtagttgaca aggagtatct tttagaaaaa atatcttcat
     2701 tagcaagaag ttcagagaga ggatatatac actatattgt tcagttacaa ggagataaaa
     2761 ttagttatga agcagcatgt aacttatttg caaagactcc ttatgatagt gtactgtttc
     2821 agaaaaatat agaagattca gaaattgcat attattataa tcctggagat ggtgaaatac
     2881 aagaaataga caagtataaa attccaagta taatttctga tagacctaag attaaattaa
     2941 catttattgg tcatggtaaa gatgaattta atactgatat atttgcaggt cttgatgtag
     3001 attcattatc cacagaaata gaaacagcaa tagatttagc taaagaggat atttctccta
     3061 agtcaataga aataaactta ctgggatgta acatgtttag ctattctgta aatgtagagg
     3121 agacttatcc tgggaaatta ttacttagag ttaaagataa agtatcagaa ttaatgccat
     3181 ctataagtca agactctatt atagtaagtg caaatcaata tgaagttaga ataaatagtg
     3241 aaggaagaag agaattattg gatcattctg gtgaatggat aaataaagaa gaaagtatta
     3301 taaaggatat ttcatcaaaa gaatatatat catttaatcc taaagaaaat aaaattatag
     3361 taaaatctaa aaatttacct gaattatcta cattattaca agaaattaga aacaattcta
     3421 attcaagtga tattgaacta gaagaaaaag taatgttagc agaatgtgag ataaatgtta
     3481 tttcaaatat agatacacaa gtggtagaag gaaggattga agaagctaaa agcttaactt
     3541 ctgactctat taattatata aagaatgaat ttaaactaat agaatctatt tctgatgcac
     3601 tatacgattt aaaacaacag aatgaattag aagagtctca ttttatatct tttgaggata
     3661 tattggagac tgatgaaggc tttagtataa gatttattga taaagaaact ggagaatcta
     3721 tatttgtaga aactgaaaag gcaatattct ctgaatatgc taatcatata actgaagaga
     3781 tttctaagat aaaaggtact atatttgata ctgtaaatgg taagttagta aaaaaagtaa
     3841 atttagatgc tacacatgaa gtgaatactt taaatgctgc attttttata caatcattaa
     3901 tagaatataa tagttctaaa gaatctctta gtaatttaag tgtagcaatg aaagttcaag
     3961 tttatgctca attatttagt actggtttaa atactattac agatgcagcc aaagttgttg
     4021 aattagtatc aactgcatta gatgaaacta tagatttact tcctacatta tctgaaggat
     4081 tacctgtaat tgcaactatc atagatggtg taagtttagg tgcagcaatc aaagagctaa
     4141 gtgaaacaag tgacccatta ttaagacaag aaatagaagc taagataggt ataatggcag
     4201 taaatttaac agcagctaca actgcaatca ttacttcatc tttaggaata gctagtggat
     4261 ttagtatact tttagttcct ttagcaggaa tttcagcagg tataccaagt ttagtaaaca
     4321 atgagcttat cctaagagat aaagcaacaa aagttgtaga ttattttagt catatatcat
     4381 tagctgagtc tgaaggagca tttacttcat tagatgataa aataatgatg ccacaagatg
     4441 atttagtaat atctgagata gactttaata acaattcaat aactttaggt aaatgtgaaa
     4501 tctggagaat ggaaggtggc tcaggtcata ctgtaactga tgatatagat cacttctttt
     4561 cagcaccatc aataacatat agagagccac acttatctat atatgacgta ttggaagtac
     4621 aaaaagaaga acttgatttg tcaaaagatt taatggtatt acctaatgct ccaaatagag
     4681 tatttgcttg ggaaacagga tggacaccag gtttaagaag cttagaaaat gatggcacaa
     4741 aactgttaga ccgtataaga gataactatg aaggtgagtt ttattggaga tattttgctt
     4801 ttatagctga tgctttaata acaacattaa aaccaagata tgaagatact aatataagaa
     4861 taaatttaga tagtaatact agaagcttta tagtcccagt gataactaca gaatatataa
     4921 gagagaaatt atcatattct ttttatggtt ctggaggaac ttatgcatta tctctttctc
     4981 aatacaatat gaatataaac atagaattaa atgaaaatga tacttgggtt atagatgtcg
     5041 acaatgtcgt aagagatgtc actatagaat ctgataaaat taaaaaagga gatttaatag
     5101 agaatatttt atctaaatta agtattgaag acaataaaat tattttagat aatcatgaaa
     5161 ttaatttctc tggaacatta aatggaggta atggatttgt atctttaaca ttctcaatct
     5221 tagaaggaat aaatgcagtt atagaagttg atttattatc taaatcatat aaagttctta
     5281 tttctggtga actaaaaaca ttgatggcaa attcaaattc tgttcaacag aaaatagatt
     5341 atataggatt gaacagcgaa ttacaaaaaa atatacctta tagttttatg gatgataaag
     5401 gaaaagaaaa tggatttatt aattgttcta caaaagaagg tttatttgta tctgaattat
     5461 ctgatgtagt tcttataagt aaagtttata tggacaatag taaacctcta tttggatatt
     5521 gtagtaatga tttgaaagat gttaaagtca taactaaaga tgacgttatt atattaacag
     5581 gatattattt aaaagatgat ataaaaatct ctctttcttt tactatacaa gatgaaaata
     5641 ctataaaatt aaatggagta tatttagatg aaaatggagt agctgaaata ttgaaattta
     5701 tgaataaaaa aggtagtaca aatacttcag attctttaat gagcttttta gaaagtatga
     5761 atataaaaag tattttcata aattccttac aatctaatac taagcttata ttagatacta
     5821 attttataat aagtggtact acttctattg gtcaatttga gtttatttgt gataaagata
     5881 ataatataca accatatttc attaagttta atacactaga aactaaatat actctatatg
     5941 taggtaatag acaaaatatg atagtagaac caaattatga tttagatgat tctggagata
     6001 tatcttcaac tgtcattaat ttttctcaga aataccttta tggaatagac agttgtgtta
     6061 ataaagttat aatttcgcca aatatatata cagatgaaat aaacataaca cctatatatg
     6121 aagcaaataa tacttatcca gaagtgattg tattagatac aaattatata agtgaaaaaa
     6181 tcaatattaa tatcaatgat ttatctatac gatatgtatg gagtaatgat ggaagtgatt
     6241 ttattcttat gtcaactgat gaagagaaca aggtatcaca agttaaaata agatttacta
     6301 atgtttttaa aggtaatact atatcagata agatatcttt taattttagt gataagcaag
     6361 atgtatctat aaataaagtt atttcaacat ttacaccttc atattatgtg gaaggattac
     6421 ttaattatga tttaggtctg atttctttat acaatgagaa attttatatt aataactttg
     6481 gaatgatggt gtctggatta gtatatatta atgattcatt atattatttc aagccaccaa
     6541 taaagaactt gataactgga tttacaacta taggtgatga taaatactac tttaatccag
     6601 ataatggtgg agctgcttca gtcggagaaa caataattga tggcaaaaac tactacttca
     6661 gccaaaatgg agtgttacaa acaggtgtat ttagtacaga agatggattt aaatattttg
     6721 ctccagcaga tacacttgat gaaaatctag agggggaagc aattgatttt actggcaaac
     6781 taactattga tgaaaatgtt tattattttg gagataatta tagagcagct atagaatggc
     6841 aaacattaga tgatgaagtg tactatttta gtacagatac aggtagagct tttaaagggc
     6901 taaatcaaat aggtgatgat aaattctatt tcaactctga tggtattatg caaaaaggat
     6961 ttgttaatat aaatgataag acattctatt ttgatgattc tggtgtgatg aagtcaggat
     7021 atactgaaat agatggaaaa tatttttact ttgctgagaa tggagaaatg caaataggag
     7081 tatttaatac agcagatgga tttaaatatt ttgctcatca tgatgaagat ttaggaaatg
     7141 aagaaggtga agcactttca tattctggta tacttaattt taacaataag atttattatt
     7201 ttgatgattc atttacagca gtagttggat ggaaggattt agaagatggt tcaaaatatt
     7261 actttgatga agatacagca gaagcatata taggtatctc aataattaat gatggtaaat
     7321 attattttaa tgattctgga atcatgcaaa ttggatttgt cacaataaat aatgaagtat
     7381 tttatttctc tgattctgga atagtagaat ctggaatgca aaatatagat gataattatt
     7441 tctatataga cgaaaatggt ctagttcaaa ttggtgtatt tgacacttca gatggatata
     7501 aatactttgc accagctaat actgtaaatg ataatatcta tggacaagca gttgaatata
     7561 gtggtttagt tagagttggt gaagatgtat attattttgg agaaacatat acaattgaga
     7621 ctggttggat atatgatatg gaaaatgaaa gtgataaata ttatttcgat ccagaaacta
     7681 aaaaagcata taaaggtatt aatgtaattg atgatataaa atactatttt gatgagaatg
     7741 gaataatgag aacaggtctt ataacatttg aagataatca ttactatttt aatgaagatg
     7801 gtattatgca atatggttat ctaaatatag aagataagac gttctacttt agtgaagatg
     7861 gtattatgca gattggagta tttaatacac cagatggatt taaatatttt gcacatcaaa
     7921 atactttaga tgagaatttt gagggagaat caataaacta tactggttgg ttagatttag
     7981 atgaaaagag atattatttt acagatgaat atattgcagc aactggttca gttattattg
     8041 atggtgagga gtattatttt gatcctgata cagctcaatt agtgattagt gaatagataa
     8101 aaatacgtta aatatatcct cttatactta aatatataaa aataaacaaa atgatacact
     8161 acataaagtg ttctatctaa tatgaagatt taccaataaa aaggtgaact atgatgaatg
     8221 cacagtagtt caccttttta tatttctaat ggtaacaaaa tattttttta tataaaccta
     8281 ggaggcgtta tgaatatgac aatatctttt ttatcagagc atatatttat aaagttagta
     8341 attttaacta tatcatttga tacattatta ggatgtttaa gtgcaataaa aagtcgtaaa
     8401 tttaattcta gttttggaat agatggagga atcagaaaag tagcaatgat agcatgtata
     8461 ttttttttat cagtagttga cattcttaca aagtttaact ttttatttat gttaccacaa
     8521 gattgtatca attttttaag actaaaacat cttggaatat ctgaattttt ctctatttta
     8581 tttattttat atgaaagtgt aagcatatta aaaaatatgt gcttatgtgg attaccagta
     8641 cctaagagat taaaggaaaa aatagcagtt ttactagatg caatgacaga tgaaatgaat
     8701 gctaaggatg aaaagtaagt aatggtagat ataataaaaa tattaacaaa taaaaagtgt
     8761 tatccaaata agaatagctg aaagttatca taattcatga aactgataat gaaaacgagg
     8821 gagcagatgc caagagacac acaagtatta aatacatata atttcgaagc aagtgttcat
     8881 tactatatgg atgacaaggt agtatatcaa acattggttc acaaagatgg tgcatggtca
     8941 gttggtaaaa tctattaagc tacattagtt acagatatca caaactataa tagttaaaca
     9001 tagaaatatg tgtaaattgt gatggaaatt attcaaaaac acaaaaatac gtgatgaagg
     9061 acaaaatgat agagaaaata agtatcaaac cttaataaat gatttaattg atagtttaaa
     9121 agttatagga aaaatatata aagaaataaa aacattaaaa aaatataaga tatgtttaca
     9181 aattactatc agacaatctc cttatctaat agaagagtca attaactaat tgagtatctt
     9241 taaattgaaa tgttaggaag tgatttaaat atgaaaactt aaattataaa aaatcaatat
     9301 taatttatct ttaaaaaata gaaaggagtg tataagattt attttcaaag tttaaaaaca
     9361 agaaaatcaa tttaaatttc agaaggaata aatgtggtta tagaagtgga tttattatca
     9421 aaaataatag tactaggagg tttttatgtc tttaatatct aaagaagagt taataaaact
     9481 cgcatatagc attagaccaa gagaaaatga gtataaaact atactaacta atttagacga
     9541 atataataag ttaactacaa acaataatga aaataaatat ttacaattaa aaaaactaaa
     9601 tgaatcaatt gatgttttta tgaataaata taaaaattca agcagaaata gagcactctc
     9661 taatctaaaa aaagatatat taaaagaagt aattcttatt aaaaattcca atacaagtcc
     9721 tgtagaaaaa aatttacatt ttgtatggat aggtggagaa gtcagtgata ttgctcttga
     9781 atacataaaa caatgggctg atattaatgc agaatataat attaaactgt ggtatgatag
     9841 tgaagcattc ttagtcaata cactaaaaaa ggctatagtt gaatcttcta ccactgaagc
     9901 attacagcta ctagaggaag agattcaaaa tcctcaattt gataatatga aattttacaa
     9961 aaaaaggatg gaatttatat atgatagaca aaaaaggttt ataaattatt ataaatctca
    10021 aatcaataaa cctacagtac ctacaataga tgatattata aagtctcatc tagtatctga
    10081 atataataga gatgaaactt tattagaatc atatagaaca aattctttga gaaaaataaa
    10141 tagtaatcat gggatagata tcagggctaa tagtttgttt acagaacaag agttattaaa
    10201 tatttatagt caggagttgt taaatcgtgg gaatttagct gcagcatctg acatagtaag
    10261 attattagcc ctaaaaaatt ttggcggagt atatttagat gttgatatgc ttccaggtat
    10321 tcactctgat ttatttaaaa caatacctag acctagctct attggactag accgttggga
    10381 aatgataaaa ttagaggcta ttatgaagta taaaaaatat ataaataatt atacatcaga
    10441 aaactttgat aaacttgatc aacaattaaa agataatttt aaactcatta tagaaagtaa
    10501 aagtgaaaaa tctgagatat tttctaaatt agaaaattta aatgtatctg atcttgaaat
    10561 taaaatagct ttcgctttag gcagtgttat aaatcaagcc ttgatatcaa aacaaggttc
    10621 atatcttact aacctagtaa tagaacaagt aaaaaataga tatcaatttt taaaccaaca
    10681 ccttaaccca gccatagagt ctgacaataa cttcacagat actactaaga tttttcatga
    10741 ttcactattt aattcagcta ccgcagaaaa ctctatgttt ttaacaaaaa tagcaccata
    10801 cttacaagta ggttttatgc cagaagctcg ctccacaata agtttaagtg gtccaggagc
    10861 ttatgcatca gcttactatg atttcataaa tttacaagaa aatactatag aaaaaacttt
    10921 aaaagcatca gatttaatag aatttaaatt cccagaaaat aatctatctc aattgacaga
    10981 acaagaaata aatagtctat ggagctttga tcaagcaagt gcaaaatatc aatttgagaa
    11041 atatgtaaga gattatactg gtggatctct ttctgaagac aatggggtag actttaataa
    11101 aaatactgcc ctcgacaaaa actatttatt aaataataaa attccatcaa acaatgtaga
    11161 agaagctgga agtaaaaatt atgttcatta tatcatacag ttacaaggag atgatataag
    11221 ttatgaagca acatgcaatt tattttctaa aaatcctaaa aatagtatta ttatacaacg
    11281 aaatatgaat gaaagtgcaa aaagttactt tttaagtgat gatggagaat ctattttaga
    11341 attaaataaa tataggatac ctgaaagatt aaaaaataag gaaaaagtaa aagtaacctt
    11401 tattggacat ggtaaagatg aattcaacac aagcgaattt gctagattaa gtgtagattc
    11461 actttccaat gagataagtt catttttaga taccataaaa ttagatatat cacctaaaaa
    11521 tgtagaagta aacttgcttg gatgtaatat gtttagttat gattttaatg ttgaagaaac
    11581 ttatcctggt aagttactat taagtattat ggacaaaatt acttccactt tacctgatgt
    11641 aaataaagat tctattacta taggagcaaa tcaatatgaa gtaagaatta atagtgaggg
    11701 aagaaaagaa cttctagctc actcaggtaa atggataaat aaagaggaag ctattatgag
    11761 cgatttatct agtaaagaat acattttttt tgattccata gataataagc taaaagcaaa
    11821 gtccaagaat attccaggtt tagcgtcaat atcagaagat ataaaaacat tattacttga
    11881 tgcaagtgtt agtcctgata caaaatttat tttaaataat cttaagctta atattgaatc
    11941 ttctattggt gattacattt attatgaaaa attagaacct gttaaaaata taatccacaa
    12001 ttctatagat gatttaatag atgagttcaa tctacttgaa aatgtatctg atgaattata
    12061 tgaattaaaa aaattaaata atctagatga gaagtattta atatcttttg aagatatctc
    12121 aaaaaataat tcaacttatt ctgtaagatt tattaacaaa agtaatggtg aatcagttta
    12181 tgtagagaca gaaaaagaaa ttttttcaaa atatagcgaa catattacaa aagaaataag
    12241 tactataaag aatagtataa ttacagatgt taatggtaat ttattggata atatacagtt
    12301 agatcatact tctcaagtta atacattaaa cgcagcattc tttattcaat cattaataga
    12361 ttatagtagc aataaagatg tactgaatga tttaagtacc tcagttaagg ttcaacttta
    12421 tgctcaacta tttagtacag gtttaaatac tatatatgac tctatccaat tagtaaattt
    12481 aatatcaaat gcagtaaatg atactataaa tgtactacct acaataacag aggggatacc
    12541 tattgtatct actatattag acggaataaa cttaggtgca gcaattaagg aattactaga
    12601 cgaacatgac ccattactaa aaaaagaact agaagctaag gtgggtgttt tagcaataaa
    12661 tatgtcatta tctatagctg caacggtagc ttcaattgtt ggaataggtg ctgaagttac
    12721 tattttctta ttacctatag ctggtatatc tgcgggaata ccttcattag ttaataatga
    12781 attaatattg catgataagg caacttcagt ggtaaactat tttaatcatt tgtctgaatc
    12841 taaagaatat ggccctctta aaacagaaga tgataaaatt ttagttccta ttgatgattt
    12901 agtaatatca gaaatagatt ttaataataa ttcgataaaa ctaggaacat gtaatatatt
    12961 agcaatggag gggggatcag gacacacagt gactggtaat atagatcact ttttctcatc
    13021 tccatatata agctctcata ttccttcatt atcagtttat tctgcaatag gtataaaaac
    13081 agaaaatcta gatttttcaa aaaaaataat gatgttacca aatgctcctt caagagtgtt
    13141 ttggtgggaa actggagcag ttccaggttt aagatcattg gaaaataatg ggactaaatt
    13201 gcttgattca ataagagatt tatacccagg caaattttac tggagattct atgccttttt
    13261 cgattatgca ataactacat taaaaccagt gtatgaagac actaatacta aaattaaact
    13321 agataaagat actagaaact ttataatgcc aactataact actgacgaaa ttagaaacaa
    13381 attatcttat tcatttgatg gagcaggagg aacttactct ttattattat cttcatatcc
    13441 aatatcaatg aatataaatt tatctaaaga tgatttatgg atatttaata ttgataatga
    13501 agtaagagaa atatctatag aaaatggtac tattaaaaaa ggaaatttaa tagaagatgt
    13561 tttaagtaaa attgatataa ataaaaataa acttattata ggcaatcaaa caatagattt
    13621 ttcaggtgat atagataaca aagatagata tatattcttg acttgtgagt tagatgataa
    13681 aattagttta ataatagaaa taaatcttgt tgcaaaatct tatagtttgt tattgtctgg
    13741 ggataaaaat tatttgatat ccaatttatc taatactatt gagaaaatca atactttagg
    13801 cctagatagt aaaaatatag cttacaatta cactgatgaa tctaataata aatattttgg
    13861 agctatatct aaaacaagtc aaaaaagcat aatacattat aaaaaagaca gtaaaaatat
    13921 attagaattt tataatggca gtacattaga atttaacagt aaagacttta ttgctgaaga
    13981 tataaatgta tttatgaaag atgatattaa tactataaca ggaaaatact atgttgataa
    14041 taatactgat aaaagtatag atttctctat ttctttagtt agtaaaaatc aagtaaaagt
    14101 aaatggatta tatttaaatg aatccgtata ctcatcttac cttgattttg tgaaaaattc
    14161 agatggacac cataatactt ctaattttat gaatttattt ttgaacaata taagtttctg
    14221 gaaattgttt gggtttgaaa atataaattt tgtaatcgat aaatacttta cccttgttgg
    14281 taaaactaat cttggatatg tagaatttat ttgtgacaat aataaaaata tagatatata
    14341 ttttggtgaa tggaaaacat cgtcatctaa aagcactata tttagcggaa atggtagaaa
    14401 tgttgtagta gagcctatat ataatcctga tacgggtgaa gatatatcta cttcactaga
    14461 tttttcctat gaacctctct atggaataga tagatatatc aataaagtat tgatagcacc
    14521 tgatttatat acaagtttaa taaatattaa taccaattat tattcaaatg agtactaccc
    14581 tgagattata gttcttaacc caaatacatt ccacaaaaaa gtaaatataa atttagatag
    14641 ttcttctttt gagtataaat ggtctacaga aggaagtgac tttattttag ttagatactt
    14701 agaagaaagt aataaaaaaa tattacaaaa aataagaatc aaaggtatct tatctaatac
    14761 tcaatcattt aataaaatga gtatagattt taaagatatt aaaaaactat cattaggata
    14821 tataatgagt aattttaaat catttaattc tgaaaatgaa ttagatagag atcatttagg
    14881 atttaaaata atagataata aaacttatta ctatgatgaa gatagtaaat tagttaaagg
    14941 attaatcaat ataaataatt cattattcta ttttgatcct atagaatcta acttagtaac
    15001 tggatggcaa actatcaatg gtaaaaaata ttattttgat ataaatactg gagcagcttc
    15061 aactagttat aaaattatta atggtaaaca cttttatttt aataataatg gtgtgatgca
    15121 gttaggagta tttaaaggac ctgatggatt tgagtatttt gcacctgcca atactcagaa
    15181 taataacata gaaggtcagg ctatagttta tcaaagtaaa ttcttaactt tgaatggcaa
    15241 aaaatattat tttgataatg actcaaaagc agtcactgga tggaggatta ttaacaatga
    15301 gaaatattac tttaatccta ataatgctat tgctgcagtc ggattgcaag taattgacaa
    15361 taataagtat tatttcaatc ctgacactgc tatcatctca aaaggttggc agactgttaa
    15421 tggtagtaga tactactttg atactgatac cgctattgcc tttaatggtt ataaaactat
    15481 tgatggtaaa cacttttatt ttgatagtga ttgtgtagtg aaaataggtg tgtttagtgg
    15541 ctctaatgga tttgaatatt tcgcacctgc taatacttat aataataaca tagaaggtca
    15601 ggctatagtt tatcaaagta aattcttaac tttgaatggt aaaaaatatt actttgataa
    15661 taactcaaaa gcagttaccg gatggcaaac tattgatagt aaaaaatatt actttaatac
    15721 taacactgct gaagcagcta ctggatggca aactattgat ggtaaaaagt attactttaa
    15781 tactaacact gctgaagcag ctactggatg gcaaactatt gatggtaaaa aatattactt
    15841 taatactaac acttctatag cttcaactgg ttatacaatt attaatggta aatattttta
    15901 ttttaatact gatggtatta tgcagatagg agtgtttaaa gtacct
//
LOCUS       DAEQJM010000078        15917 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.079, whole genome shotgun sequence.
ACCESSION   DAEQJM010000078 DAEQJM010000000
VERSION     DAEQJM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.079"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(253..1143)
                     /gene="metA"
                     /locus_tag="KRQ43_003100"
     CDS             complement(253..1143)
                     /gene="metA"
                     /locus_tag="KRQ43_003100"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBH2743442.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            complement(1173..2438)
                     /locus_tag="KRQ43_003101"
     CDS             complement(1173..2438)
                     /locus_tag="KRQ43_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HBH2743443.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     regulatory      complement(2548..2650)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(2704..5361)
                     /locus_tag="KRQ43_003102"
     CDS             complement(2704..5361)
                     /locus_tag="KRQ43_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH2743444.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNFSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKRKK"
     gene            complement(5489..6232)
                     /gene="yaaA"
                     /locus_tag="KRQ43_003103"
     CDS             complement(5489..6232)
                     /gene="yaaA"
                     /locus_tag="KRQ43_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBH2743445.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIIN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            complement(6242..6706)
                     /gene="bcp"
                     /locus_tag="KRQ43_003104"
     CDS             complement(6242..6706)
                     /gene="bcp"
                     /locus_tag="KRQ43_003104"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBH2743446.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            complement(7058..8755)
                     /gene="ade"
                     /locus_tag="KRQ43_003105"
     CDS             complement(7058..8755)
                     /gene="ade"
                     /locus_tag="KRQ43_003105"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBH2743447.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIASLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            complement(9061..10215)
                     /locus_tag="KRQ43_003106"
     CDS             complement(9061..10215)
                     /locus_tag="KRQ43_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HBH2743448.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKFYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            complement(10460..11299)
                     /locus_tag="KRQ43_003107"
     CDS             complement(10460..11299)
                     /locus_tag="KRQ43_003107"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBH2743449.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFNNSKKYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            complement(11312..11908)
                     /locus_tag="KRQ43_003108"
     CDS             complement(11312..11908)
                     /locus_tag="KRQ43_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH2743450.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            complement(11959..12609)
                     /locus_tag="KRQ43_003109"
     CDS             complement(11959..12609)
                     /locus_tag="KRQ43_003109"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBH2743451.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGVDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            complement(12655..13908)
                     /locus_tag="KRQ43_003110"
     CDS             complement(12655..13908)
                     /locus_tag="KRQ43_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH2743452.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEKENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLREIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            complement(13932..14573)
                     /locus_tag="KRQ43_003111"
     CDS             complement(13932..14573)
                     /locus_tag="KRQ43_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH2743453.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            complement(14775..15188)
                     /locus_tag="KRQ43_003112"
     CDS             complement(14775..15188)
                     /locus_tag="KRQ43_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HBH2743454.1"
                     /translation="MIELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNLYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            complement(15339..15680)
                     /locus_tag="KRQ43_003113"
     CDS             complement(15339..15680)
                     /locus_tag="KRQ43_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBH2743455.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
BASE COUNT         5009 a         2840 c         1674 g         6394 t
ORIGIN      
        1 ccctttttaa tctcttttaa aagttaaaat acaaatttat tgatactata aaggtttagt
       61 ctcccattat cgcaccatat ataaaattaa aaccacctct atctacatac acctaaagtg
      121 attttcttaa aatataaaac tactattata aggttaaatt taaaaaaaat aaggtataaa
      181 gtatcattaa gattaacttt atacctataa atttctatat ttttttagtt aacatttata
      241 tactcttaaa atttattgta tcaaatagtt ttttatccaa tttctaaaca acaattctga
      301 atgttttttc cattttacag ttggctcttc tgaagggtca tcattaatat agtaattttg
      361 aggtatagat attttatctc ctttatttat atccctctta tattctttat caagagtgta
      421 tttgtcatac tcgctatgac ccattacgaa cacatctctt gaatttgtaa ttatataggg
      481 accagcttct ttagaatgac tcacaatgct caactcttta ttctctttca aagcttcaat
      541 atttacagta gtatgtcttg aatgtggagc aaaaaattca ttttcaaatc catctactat
      601 tttactatct ttatctacct tatgcttaaa tactccaaaa catttttgac ttagtggaag
      661 tttttttaca ttgtagtatt tgtaaagact tgcttgagct gcccaacata tatataatgt
      721 agatttagtt tttctcttag aataatccat aatttcttct agttcattcc aataatcaac
      781 ttcttcaaac tccatttgtt caactggagc tcctgttatt ataaagccat caaaatactc
      841 tcctttggct tcatcaaatg ttttataaaa ttctttaaca tattcattac aacttctttt
      901 actttctctt gttgaaattt taataaattc aacagacacg ttgaatcctg ttttatctat
      961 ccttcttagt aaatctaatt ctgtatctat ctttataggc attagattta gtatagctat
     1021 tttagtgtct atgttttctt catactttaa ttccttttta aaatcttctt tataaattac
     1081 atctattcct tcatctaata atttattaat aacaggtaat ccctttggta gtattaaagc
     1141 catatctttt cacttctctt tctcttagaa tattagaaat ttaaagcttg atttaaatca
     1201 gctattaaat cctctacatt ttctattcca acagataatc ttattagtga aggcaatact
     1261 ccagatgcaa ttaattgttc ttctgttaat tgtctatgag tagttgaagc tggatgtata
     1321 acacaagttc ttacatctga aacatgtgta accaaagatg ctatctgtaa tttttccaca
     1381 aattttttgg cattttctaa cccacctctt actccaaatg ataaaacacc actacatcct
     1441 cttgataaat actttttggc attctcataa tacttgttat cttcaagtcc tgggtaatta
     1501 atccaatcta cattttcatg tttttctaaa aatctagcta ttttaagtgc attttcacta
     1561 tgtctctcca ttctaagatg tagtgtttca acatttaaat tagtaagata cgcattgaat
     1621 gggcttaaac aatttccata gtctctaagc aactgaactc ttgctttagt tgcatatgcg
     1681 gcatttccaa atttttgagt atagcttatt ccatgatatg ttgggtctgg ctcaactaat
     1741 tctggaaatt ttccattatc ccagttaaag tttccaccat ccactataat tcctccaaca
     1801 cttgaagcat gcccatctaa atattttgtg gtagaatgag taactatatt tgctccatac
     1861 tttaaagggt tacaaagcac tggagatgct aatgaattat caacaataaa tggaacatta
     1921 attctcttag ctacatttgc tattttttca aaatctatga cttcaagagt cggatttgca
     1981 agtgtttctg caaatacaac cttagtattt tcctttgcaa gttctactat ctcatcttca
     2041 cttgaatcta agtcaaacga tattaaatct ataccaaatt ttttaagact aggtcctagt
     2101 aaattgaatg ttcctccata tacttttgaa gaacaaagta tactatctcc tgatttacat
     2161 atatttaaaa ctgccaacat atttgcagat tgccctgatg atacagctac agaagatact
     2221 ccaccctcta gtaaacttat tttttcttca aaagcttgaa tagtaggatt gcttattctt
     2281 gaatatatat gtccatcaac ttttaaatca aataattcag caagttggtc tatactgcta
     2341 tatttaaaag ttgtactttg atataaaggt aatactcttg gttctccatt acctggttta
     2401 taatttcctt gcacacatat tgtttcttta ttatacattc ttgtatcccc cttagatttt
     2461 agtaaaaaaa attaaactat ttatcagatg agagttaaaa taaataaagc ctgagtatat
     2521 aactcaggct ctgtataagc ttaattatac tcatctctca gctttcgccg caggatttag
     2581 caccaatgta tataaatata ctggttgccg ggtttcatag ggccagtccc tccacctctc
     2641 tggataagat ttatttaatt tttctatgtt ttatatctta tatatttttc ctaattttgt
     2701 caactatttt tttctttttt ttcttttaat aattttccca acctctactt gaattacaga
     2761 cattatggct aaaacaatcg ttataagcca ctctaagtta tttaaaactg ttaagttaaa
     2821 agcatttcta aaaacaggta caaacagtat tactgctatt aaaaatgcag aagttaaaaa
     2881 tgagattaaa agaaatggat ttttaccatt atttctatta aacattgaat ctgtatttga
     2941 acgctgacta aatgctcgta acatctgtga aaatgctaat acacaaaatg ccattgtttg
     3001 acctacagaa tgattttcta tattaagacc aattttatat gctaaaatag tcattattgc
     3061 cacaaatata ccttgggtaa caactctttg tataagattt ttttcaaaca aagtggttga
     3121 tttcactggc tggtgcttca ttatatttct gcttggtggg tcaactccaa gagcaagggc
     3181 tggaagcgta gcagttgcaa ggtttaccca tagaatatga acagcaagaa gcggagtatc
     3241 ccaatttaat aatattgcta caaacaacgt aagtatctct gctatattac caacaagcaa
     3301 aaattgtata actttttgta tgtttctata tacacgtcta ccttctttta ttgcataagc
     3361 aattgttgta aaactatcgt ccattaaaat catgtcagaa gaatcttttg caacatctgt
     3421 accacttata cccatggcta taccaatatc agcagacttt aaggcaggag agtcatttac
     3481 accatcccca gtcattgctg gtacttctcc aattcttttt agagattgta taattctaag
     3541 tttatcaaac ggggacacac gagcaaatac tgtagtattt ttaacagctt catctagttc
     3601 atcatcacta aaattatcaa gttcatcacc agatatcaca gtattttctt cactccatat
     3661 tcctaactca tgagcgattg ttgtggcagt aactttatgg tcacctgtta tcattatggt
     3721 tcttatacct gcttctttac aagtacttac tgcatcaatt acctcagttc ttggtgggtc
     3781 aatcatacca accataccta taaatgtcaa atcatattct atattttcac tatcttcttt
     3841 tggtatagat gaaatctcac gcttagcaaa accaagtaca cgcaatgcat ctttagacat
     3901 gttaagacat aattcgtgta tattcttttt atccacttcg gtaatgtttc tttcaccttt
     3961 tgaagttaat attttagtac ataggtcgag aatttcgtct actgctcctt tagtataagc
     4021 aataatcttt tcatctatat tatgaacagt tgtcatacat tttctatctg aatcaaaagg
     4081 ctgttcaaat acacgtggat attcttcttc aagagcttct tgatctattc caaatttttt
     4141 ggccataaaa attaatgcgc cctctgttgg gtcacctaat atttcatctg ttttatctgg
     4201 attaatacat gcatcattac aaagtgcacc agcataaaca atctctttat acactaatgg
     4261 atgtttttca gatgcagtat ctattgatgt cacttttcca gattcaaaat ctccattgac
     4321 agcaatatgt gtaacagtca ttttatttaa ggttaatgta ccagttttat cacaacatat
     4381 tactgtagct cctcctaatg tttcaacagc aggtaatttt ctaattaaag catttctttt
     4441 agccatacgc tgtacgccta aagccattac aatagtagct gttgcaggta atccctctgg
     4501 aataattgat atggcaaggg aaattgcaat cataaacatt ggcaagagag gtctctgata
     4561 aaatgcacct attgcaaata taacaacgca tacaataata cctatgacac ttaatgtctt
     4621 tccaacagta ttaagtttac gttttatagg agtatcaaaa tcatcttgtg aatctaaaag
     4681 atgtgctatg ttacccactt ctgtatccat accagttgct actacaacac ctacacctct
     4741 accatatgtg actattgaag atgtatacgc catattgcta cggtctccta atacacattc
     4801 tttaggtaag attgtatctg catctttttc tgatggaaca gattctcctg ttaaagaagc
     4861 ctcttgaatt tttaaacttg atgtttctat taaacgaagg tctgctggaa ccatagctcc
     4921 atcttctaaa aaaacaatat ctcctactac aagattactt gctggaataa cattttcttc
     4981 accatcacgc ataacacgag ctgtaggtga gttcatattt tttaatgctt ctaatgatga
     5041 ttctgctttt ttctcttgaa caattccaat aactgcattt actgttacaa ttattagtat
     5101 tacaaaagct tctgtaaatt cgccaaatat caaagataat attgctgctc ctattagtat
     5161 cataaccata gcatctgtaa tttgactcca aagcatttgt aaagttgttc taggtggttt
     5221 ttttctaagt tcatttaagc cattctcttt aagccgtttt tccgcctcgg tatcggtgag
     5281 cccctcctct gatgaatcta gactttctaa aatttcatgc gttgctcttg aatgccaagg
     5341 catctgtttg tgattttcca ttttggaaga ccactccttt ctttttttaa tttaagaata
     5401 attatatttt aaaatcaagt tcaattcaat acacactaag tatattttac ctaaatttaa
     5461 caatgccatt taatatttaa caaaacttct actcttttac aaatatgtat tcactattgt
     5521 tagataagtt ttctttatac ttataacctt ctaaattaaa ctttttcagt tcttcaatat
     5581 ctcttatcct attttttaca atgtattttg tcatcatacc tctagctttc tttgcttgtg
     5641 tagattccac tttcaatatg ccatttttat ttactttaaa agtacatgta atatatgtat
     5701 cactatcttt aataaatttt tctatggact tgctgtattc atttgatgaa agattaatga
     5761 tagctgtttt ttctttgatt agttctttat atatacgatt tccccaatat tcgtataaat
     5821 tcttaaactc acctactcgt aattttgtct gcatttctaa tctatattca tatatactat
     5881 catatggttt tacaacacca tacaatccac ttatgattcg aatacagcta tttgcaaact
     5941 cttcatcttt ccttgtaaaa ttttctgctt ctatattttt atattgtatt ccatcataag
     6001 ttaagattgc agggtttcct aatctatcaa atttaatgct ttcaaatcta tttttattta
     6061 atacagctaa tttttcatta attttcattt tatttttaaa atcttctata ccaaatgtct
     6121 ttatattttc cactatttct tttgtgttat ctataaaaca aggcaaactc aaatctctat
     6181 caaatacttc tatattcttc atatttttag ctggtgataa cattataatc ataaattctt
     6241 attactcctg tttttccaaa tattcaagaa tctcttgtgc atttgtgtct ggttttgctt
     6301 tttcaaagac tttttcaata attccatttt catctataat atatgtcgca cgtacaactc
     6361 ccaatgcagt ttttccatac atttttttct ctttccatac atcaaaagct tttatagcaa
     6421 ctaagtcagg gtcagaaagt aaaataaaag gaagttcatg cttttctgca aatttttgat
     6481 gtgattttat actatcttta cttatcccaa taacttgtat atcttccttt ttaaatccat
     6541 catatgcatt tctaaaagca caagcttgac gtgtacatcc tggtgtatta tctttaggat
     6601 aaaaatatac tactactttt ttgcctttaa aatctgacat acttacctta tttccatctt
     6661 tatcttctag tgtaaattct ggtgcttttg ttcctatact caacataaat atctctcctt
     6721 ttgtttttat taataatttt atactatgct tatattatta ccctataaat ctatatataa
     6781 ataaaatatt ttatttttta tgtataaagt ttcataaata tataattttc atgtatttat
     6841 attctaaaat agactgaaaa tagttttatt aagatatcta tgcttaaaac aaggttaaat
     6901 gatagattaa ttaaaataag gatatctaaa aataaaattt ttagttcatt agatgctctt
     6961 ttttgtatga aatcaaatat attttcatca tttcaacaat aaaaagagac ttatccctat
     7021 tttgagaaag cctcatttat tattactttt atattatcta tataaattta aattcctcaa
     7081 catcaaatag acctaaatct gtaagtctta tttgtggaac aactggaagt gccataaaag
     7141 aaagtgtaat aaaagggtct acatactctg gaactcccat ttttcttgct atctccaaca
     7201 tattatcagt aatttcttgt acttcttcag ctgtaaaagt actaattaat ccagctactt
     7261 gaagacttag gtgtgcaaga acttttccat ttgatacaat tacataacca ccttgtattt
     7321 cctttaagta atttatagct actagaatat catcatcatt atcccctgca actataatat
     7381 tatgagaatc atgggccaca gtagtagcaa ttgctccatt ttttatgcca aatcctttta
     7441 gtgaagcaat tgctacattt ccagtcattc tatgtctctc aacaacacaa agttttgaat
     7501 actctttatt tggaacaaaa tatccatctg cacatggtaa agattcatat accttatttg
     7561 tcaaaatttg ataaggtaca atctccatta cataattttt ttcacttact tttaactgta
     7621 ttttttcttt attaatatac ttaaacttga ctgtattaag caattcttta tctttaatct
     7681 cataattgta attagaaaac atctcttcgt ttaccaaatt accatcttta tatacactat
     7741 ccacttccat tttgtctaaa tcattcaata caacaatatc tgccttataa cccgcaccta
     7801 ttgctccaat tttccttaac ccatatgctt ttgcagaatt ataagttgca acttttatag
     7861 ccctaacagg ttccatacct aaatcaatcg cacattttat attccatctt atgtgacctt
     7921 gtttttctat atcatctaag tgcttatcat ctgtgcaaaa cataaattct tcaattggca
     7981 agttatgctt tagcatacca cttactatag actttaaatt ttttgctgcg cttccttctc
     8041 ttattaaaat ttttaatcct gctctcaatt tttcatatac ttcatcaaaa gttatacatt
     8101 catggtcatt ttctattcct gcacatacat atgtctgaag tgatttacca tttatattag
     8161 gtgcatgtcc atctacaact ttatttttaa aaagctctag tttatccaag atttcatttt
     8221 cagaatttat aacatcatta aaacacatta cctctcctaa acctaaaatt ctaggattat
     8281 ttacataact ctccatgtct tttgcactaa atttaccaac tccattagtt tcaaaacttg
     8341 ttgcaggtac ggatgaaggc accataatat atacattaag tggtatatct tttgtcgatt
     8401 ctaataaaaa atctattgca ctagctcctt ttacattgac caactcatgt gggtcggcta
     8461 tgatagttgt cgtacctgat tttaataatt ttttcgataa ttcaattggc attaccattg
     8521 tagattcaat atgcatatgt gcatcaataa agccaggtga tatatattta ttgctacaat
     8581 caatttctac attgcccttg taatcgccaa tgccaacgat agtgtctcct actattgcta
     8641 catctcctgt tattaactct tctgtaaata catttatgat tgtcccattt tttagtacaa
     8701 tgtcagcttt ttctcttcca cttgaaacat cacactgtct ttttaaatta cccattttta
     8761 caactcctcc taagtttttt atatcaatat actggctgta ttacgtatta tagtttaatt
     8821 tattaatata tattatatat gagttttgat agaaagtatc acttgaaatt tgttccataa
     8881 ttcctttaat taaatagaga gaacatgagg aataatatta tctcccatgt tctcattaat
     8941 atttaagcaa taatttaatt catattgaat tttttatttt tatatttaat cttcactatt
     9001 cttataaata aatttatgtg ctttattatt tttttaatac ttctttattc gtaattatat
     9061 ttaacctaaa aatgcataaa ctatcatacc tacaagtatt gctggtatag tagtaataat
     9121 catagcccat aaagaagatt ttttatccat tgctaaaagt gggaaaagtg catctccatc
     9181 ttgagaaata gagttggcta tcactgcacc aagtggtata gttcccttca aataaaatga
     9241 cataagcaca atttgtatcc cacaacctgg aataagtcca agacctgcac ctataaatac
     9301 acttattaca cctgttgata atactagttt aactaagtat tcatctccac ctaaaattaa
     9361 tattatcaaa tcgtaaataa gatatgcaat aaaaatccat gtaattacaa atgatatttc
     9421 tccaacagaa tggataagca tttctcgcaa agaaatcttt ttattttctt cctctttttg
     9481 attagaattt ttaaatacct ttttaaaaca ccacatataa attattgaaa ataatattcc
     9541 aatcactgct attacttctt ccaatgaatg taacttctca attataggaa gattaagtcc
     9601 agagtgagca agtgacataa atataaaacc gattactata attcctatat aaaatttata
     9661 tccctttcca tgtgttatta taaatgcaag tctatttgta tttccatgag atttagctag
     9721 agtgtctaaa attatttcat catgattatg ttgttcttta ttttctttag ggttattttt
     9781 acttatatca tatttatctg attttctacg gttttttaac cctaattttt cttctagttt
     9841 aaagtaatcc actaattgtc ccgttattat tcctgtaatt gtactaacta tagtgacaaa
     9901 aaaatacatt ttaatatttg atgaaataag tacaaatgct gcatctccca tactagctat
     9961 taaacttgca attattgctc caaagcttaa ttttccattt atatacaatg gcattattgc
    10021 cagacttccg ccacaacctg gtatagctcc aattaaagca cctattaagg gttgaaattt
    10081 tctgtttttt gatatgatat tagtaaaatt tccactagtt ttataattaa tatatccaaa
    10141 taacaaaata aaaaatccaa tcatagaacc tacatgtaaa aacgcctctt cagaagcgga
    10201 tatcaacatt tccattaatt tacctcctag actaattttg caacaattat attatattct
    10261 attttctatt gataatcaat atcaatattt cttttgaatt tttaatatta aaaagtgcgc
    10321 atcttatact cttagttttt catcttaaga tacacacttt ttgatattag gttatctatt
    10381 taccacatgt aatatgaaat caaaggtgga tattatgata aattataaca atgtccacct
    10441 atttttatta cctatcaaat tataaatttt caaggaatgt tacaacttct tctattatcc
    10501 aattaggtgt agatgcccct gctgtaatac ccaaattttt atatttttta agcgtattta
    10561 catccaattc atctttagtc tctattgcaa aagttggtac taagtcttca caaaccttta
    10621 ctaacttttg agtatttgaa ctgtgtttac ctcctataac tatcatacaa tcaacttctt
    10681 tagctaactc tttagctgat tcttgtcttg tttttgtagc tgaacaaatt gtatcattaa
    10741 atactatttc ttctaattta tctgatagtt tattaactat acttatatac aactctggat
    10801 ttattgtagt ctgtgcaaca agacaatatt ttttggagtt attaaattcc atattttcca
    10861 tttgttctaa ggtctttatt attatagctg aattttcaca ccatccattt atacctataa
    10921 cttctggatg cttcatatct ccaataacta ttatttcata gcctttatta tgatattcac
    10981 ttactactgt atgtattttc tttacaaatg gacatgtagt atccacaatt tttaattttt
    11041 tatctttggc ttccttatat atattttcag gaactccatg agaccttatt atcatatttt
    11101 catgatttgg tattgtatca atttcattca cagtcttaag acctttttct tcatattttg
    11161 ctactgcttg cttgttatga ataagaggac ctaaagcata tatgccagaa tcattttttt
    11221 caacttcatc ccatgccatt ttcattgctc tttttactcc aaaacaaaag ccagcatttt
    11281 ttgctatttt tatgttcata actttacccc cttattttga atatttaaag taattttgtt
    11341 ttatcacttc taaaatctct tgtgatatcc tttcatggtc atcattactc aatttttcct
    11401 taaaatgttc ttcaaatgat attggttctc caatatatac aattacttta ctaaaaagtt
    11461 tatatttaga tattattgat actggaacaa ctttagattt actttttatt gtaaatacag
    11521 aaagacctgc cttagcctta ccaaaagaat ctccttttat tctagtaccc tctggaaata
    11581 ttcctaatac ataaccatct ctaactgacc ttaaaatagt ttttattgta gatacatctg
    11641 gtttttctct atttataggc ataacatgca atttttttaa tataaatccc aatggcttta
    11701 ctttaaacaa ttctttcttt gcaattgcag ctatttccct attttctatg gcagcagcca
    11761 agaatatagg gtcaagattc gatttatgat ttgatgctat tactatattt cctctatctg
    11821 gaatattctc tgcacctata acttcatatt taaaaaatat tttagaaaaa cccttaaaaa
    11881 tatttattac aaatctataa aaattcacgt ttatctccct tcaacactac atttattttc
    11941 attatgatgc ataaaaaact aaagatttat tttagataca acttcttcta caacttcttc
    12001 tatagttttt cctgtagtat ctatttctag tgcatcatta gcttttacca atggtgcaaa
    12061 ttctctattt gaatcaattt catctcgtct tattatatcc tcaattactt cttctaaagt
    12121 agtattatat cctttattac aaagttcttt atagcgtcta tttcctcttt cttctggagt
    12181 agctactaaa aagaatttgt aatctgcatc tgggaaaaca tatgaaccta tatctctacc
    12241 atctagtatt actgaacttt tcattcctat ttttcgttga acttcaacca tcaactgtct
    12301 tacttctttt atttttgcta cattagaaac attattgctt acttctattg ttcttatttc
    12361 ttcatttata acttctttgt ccaaatatat attgttatct ttaaaatcta tatccgaatt
    12421 ttcagctatt tgaataactt ctttttcatt attgacatca acaccacttt ttaaacactt
    12481 ataagtaact gctctgtaca tagcacctgt atctatataa tttatattta gcttttttgc
    12541 tactatcttg gctattgtac tttttccagc tcctgctgga ccatctacag ctataactaa
    12601 attacccata tatacacctc tatttattca tatttaatta ttaaaaaatt atatttatac
    12661 acttataccc gcaagatatc cagttgaaaa tgctatttgt aaattatatc caccagtttc
    12721 tgcatctata tcaattactt cacctgtaaa aaataagttc ttaactaatt tagattccat
    12781 agtagaagaa ttaatttctt taactgaaat accaccagaa gtaaccatac cagtgtttat
    12841 acctgtagtc ccattacaag ttagcttcat attttttata tactcaataa ttctaatttc
    12901 atctgcctta gacaaatcac ttgccttttt atcaactaaa gataatagag aaaaaatctc
    12961 tcttaagaaa ttttgaggta gtatttgctt aagattattt agaacatttt tatttggaaa
    13021 tgctctgatt atactagaga tttcatcagt acttaaattt ggtaagaaat ctatatttaa
    13081 ttctaccttt tccttttcaa taatcttgtt aatataagaa gacattataa gaacacaagg
    13141 tcctgttatc ccaaaatggg caaatagcat gtctccagat tttgatattt tccttttctt
    13201 aatcttacaa gatatttcca cattcttcat ggatattcct tgtaaatctt taatccattt
    13261 ttcctctatt gtaagtggaa ctaaagcagg atatagtttg tttaatgtat gtccatgctt
    13321 tttaagaatc ttatacattg aaccatctga acccgtcttt gaataactca ctcctccagt
    13381 tgatataata accttgtctc ctagtatctt atctccatta tctaaaataa tcccttttat
    13441 tagatacttt gacttgtcct tattagaatc atcttttaga gcaatttctt cagttataat
    13501 atctataact ttcttattat acattatctt tacattgtga ttgagtaaat ctttatttaa
    13561 tacttctatt acttctatag atttatcatt tttagtgtat actttgtggt cattttcttt
    13621 ttcaatctta tattccaaat ttctactttc aaaatacgaa ataaggtctt tatttgtaaa
    13681 tgtatagaaa ctactataga gaaatttttt attactgaca actttatcaa aaaaatcttc
    13741 tatctctcta ttattggtaa aattgcatct accgccacca gttgccctaa gttttcttcc
    13801 taattctcca tttctctcaa ctaatattac ttcattattg ttttttgaag ctgacaaagc
    13861 tgccatcatt ccagaagctc ctccaccaac tactataact ttactcataa atttctcctt
    13921 ataattgatt cctactccag tgcagaatta tttatcttta catgattttt tatatgactt
    13981 gtatcattca tttttactat aacaggtcca taatctttaa attctactat atttaaagca
    14041 gtattatctt gcttaattct atatatattt tccatacctg attctaaaaa tgacaacaac
    14101 ataaccctca atgtaattga atgtgtaaca agaattatat ttttattatc atatttttca
    14161 tttagttcct ttataaaagc atctactctt tcctttataa tcttaagagt ttcgccttct
    14221 ggtatattta ctaagtgtgg ttcatttctc catgttgcat atatatctga ataatctttt
    14281 tgaatttctt ttattaaaag gccttcccaa actccgaatc ccatttctct aagtgcctca
    14341 gttttttgaa cttcaatatt gagcttatct cctaaaattt gagctgtttg cattgctctc
    14401 ccaaggtcgc tactaaaaat ataatcaatt gaatacttgc caatatcttc agaaagttct
    14461 tttgcctgtt ctataccttg aggcgtaagg tcagaattac catgaccttg tgtttttccc
    14521 aatatattcc aatccgtttg tccatgtctt actatataaa aagtatttcc catatgtcct
    14581 cctaatatat gcctattttt tattaaatat aaattatcac ttctcaaaac ttaattatat
    14641 catataatac tttactttgt ttctatttta taatctaatc taacatatta tttacaataa
    14701 atctcatttg tatttctgca aattattgta ctgttaaaga atttttctaa atttataaac
    14761 atatttctct tatattattt atatacttct tcaaatctgt attcttgaat tgaattgaca
    14821 tacttatctg tatctacttt ttctaaaaac atatccaaag gtcttgcaaa tattcctgta
    14881 tcatcatata aggtcttgta taaaactaaa tcattagtat cttcttcttt tttatgataa
    14941 aggtttccat ctaaatccct ataaacatag atatcttctt ctctttcagt atgtctaata
    15001 actaatttat atttatttct gttttggatt aaattttctt taccatatat ttcacatatg
    15061 ttttctatat catcaatagc cttgctaaga cccattgtag cataatattt ccctttaaaa
    15121 tgtttataga tacaaggata ttttaacttt ctttcactga tacctaagtt attctttaat
    15181 tcaatcattt tattataatc tcccatatct cgtccctttc ttttaaaaag tattttattc
    15241 tgaaataagt tacttgtttt atattttatc ataatttaaa atttattaat aatacaatca
    15301 ataaataaag aggctgtata aaatacagcc tcccaatatt aatcttcata atcatataat
    15361 ttttctaatt tcttttttaa tttctttttt ctttctgaac ctaaaattct tataaaatta
    15421 ttattcacaa aaatacaatt attgctgaga taaaattcac acttgtctag atttacaata
    15481 taactattac tgcatttgaa aaaattttct tctttcaata gttttcttat acaaggagca
    15541 ttttctccaa cttcataatt accactttca gtataaatct ttacttcata ctcttgcttt
    15601 tctatgtaca aaacttcttt actattaatt gaaaaacgtt tatcctcgta ttcaacatta
    15661 ataaaatttt cctctttcat ttccatccct ccaagtactt ttattaattt aattttagtg
    15721 ttttttatca atataatcta tcggaaatat atgtaagact gatttactta agatatttaa
    15781 ataattatta ttaatattaa tgtataagtt tattttttaa cattaatttt taaagttaaa
    15841 aagacttttt ttaatcatat ccgtatatat aagtatatct atctttaata aaataacttt
    15901 tatagaaatt catgtaa
//
LOCUS       DAEQJM010000079        15248 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.080, whole genome shotgun sequence.
ACCESSION   DAEQJM010000079 DAEQJM010000000
VERSION     DAEQJM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15248
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.080"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            217..864
                     /locus_tag="KRQ43_003114"
     CDS             217..864
                     /locus_tag="KRQ43_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH2743456.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTAFKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(1031..1600)
                     /locus_tag="KRQ43_003115"
     CDS             complement(1031..1600)
                     /locus_tag="KRQ43_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743457.1"
                     /translation="MKKFILCIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(1605..2504)
                     /locus_tag="KRQ43_003116"
     CDS             complement(1605..2504)
                     /locus_tag="KRQ43_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2743458.1"
                     /translation="MKLLSKVNNNIRLIIQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(2515..2664)
                     /locus_tag="KRQ43_003117"
     CDS             complement(2515..2664)
                     /locus_tag="KRQ43_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743459.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(2657..3241)
                     /locus_tag="KRQ43_003118"
     CDS             complement(2657..3241)
                     /locus_tag="KRQ43_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBH2743460.1"
                     /translation="MKKFFMVVLGCIFVLGVISGCSKKESKPVEKNKSNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKNIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEEWKKIIDERLKMVKANE"
     gene            3662..4987
                     /gene="cdeA"
                     /locus_tag="KRQ43_003119"
     CDS             3662..4987
                     /gene="cdeA"
                     /locus_tag="KRQ43_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HBH2743461.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GISFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFNYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIIALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKGRYKY"
     gene            complement(5082..5876)
                     /locus_tag="KRQ43_003120"
     CDS             complement(5082..5876)
                     /locus_tag="KRQ43_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743462.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(5877..6752)
                     /locus_tag="KRQ43_003121"
     CDS             complement(5877..6752)
                     /locus_tag="KRQ43_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743463.1"
                     /translation="MRSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(6756..7124)
                     /locus_tag="KRQ43_003122"
     CDS             complement(6756..7124)
                     /locus_tag="KRQ43_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH2743464.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(7307..7966)
                     /gene="deoC"
                     /locus_tag="KRQ43_003123"
     CDS             complement(7307..7966)
                     /gene="deoC"
                     /locus_tag="KRQ43_003123"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBH2743465.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(8002..9546)
                     /gene="murJ"
                     /locus_tag="KRQ43_003124"
     CDS             complement(8002..9546)
                     /gene="murJ"
                     /locus_tag="KRQ43_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH2743466.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILITGIIFIGITSVMSAFLQIKENFIVVGF
                     GSIPYNIVIIISIMLSTVFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKD
                     DSLIKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYSDRLNGFVTGTFTA
                     SIVSVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFER
                     GAFDARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVL
                     DLVLIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIM
                     GVLSYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKR
                     KLHLKK"
     gene            complement(10020..10904)
                     /locus_tag="KRQ43_003125"
     CDS             complement(10020..10904)
                     /locus_tag="KRQ43_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2743467.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(11195..11671)
                     /locus_tag="KRQ43_003126"
     CDS             complement(11195..11671)
                     /locus_tag="KRQ43_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBH2743468.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGVLDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQAKDLEEHHHHDKNCGCGCNHHHEN"
     gene            11938..13113
                     /locus_tag="KRQ43_003127"
     CDS             11938..13113
                     /locus_tag="KRQ43_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HBH2743469.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(13194..13997)
                     /gene="proC"
                     /locus_tag="KRQ43_003128"
     CDS             complement(13194..13997)
                     /gene="proC"
                     /locus_tag="KRQ43_003128"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH2743470.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINNEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(14037..14621)
                     /locus_tag="KRQ43_003129"
     CDS             complement(14037..14621)
                     /locus_tag="KRQ43_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743471.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         5167 a         2480 c         1678 g         5923 t
ORIGIN      
        1 tatgttttat aagtatttct ttattcagtt atttgttaaa aactaatagt aaatcttata
       61 ctaatcgcat atttatgtta taactatatt gtaactattt tcgtaatctt aggaaaagat
      121 tacttataaa attaacctta tacaataata tatcgtataa tcttaattag cataatagtt
      181 acaatattaa aatttaaata tgggagtgat tttagtatga taagacaaac accattagag
      241 aaacgatatg acaagctagg tcctcatatt gtaacagcat tcaaaaaacg ttattttgat
      301 gcttattact gtaaaactag aaatgaagct ttgcaacaaa ttttagattt aattcctcaa
      361 aatcatgtag tatcatgggg aggatctgaa acacttaaag aaatgggcgt acaaactgct
      421 gttagagaga aaggatttaa agttattgat agagatttag caaaaactcc agaagaaaga
      481 actgaaatta tgcgtcaagc acttctatgc gatacttttt tgatgagtag caatgcaatt
      541 agtgaagatg gacaactctt taatattgat ggaaatggca atcgtgtagc tgcaatgata
      601 tttggtccaa aaaatgttat agttgtagct ggtatgaata aaattgtaaa aaacattgat
      661 gatgcaatac aaagaactag aacaattgca tctccagcag ttgttcagcg ttttcaagat
      721 gtcaatacac catgctatat taatggaagt tgtatagatt gcacaagtcc tgaaagcatt
      781 tgtgcataca tggttactac aagaatcagt cgtccagcaa aaaaaataaa ggtaatattg
      841 gtaggagaaa atcttggtct ataaaatata catacatgta aatagctcta taaataataa
      901 aatcatatga aataacttat ttctaaaagt ggtagaataa aagcttctac aagactttca
      961 ttctaccact tttatattct tttaatttgt gtttctatat tattaattgc tccaattttc
     1021 atatatatta ctaactattt ttattttcat aatttttttg ttcttcatca agctgtttat
     1081 aataatcttt attatagtca gctagataat ctataccacc tcctgtaatc acatttaata
     1141 atttcattgc agattcttga ttaactttac aaacataatt atcaccagat ttaacaagct
     1201 ctaatgtaat attaaattct tttttctttg cagaatcaat atctttcata gttggatttg
     1261 gcatcatttc tcctagttta ggaggattct tttttaaaat agaaaccata tcagtattgt
     1321 taatttttaa atctacagtc actttatcct tattattctt tatatctgaa atttcccaag
     1381 tcatattttt agaatacatt ttaaatcctt ctttatcttc gtatataaga ttacctaacc
     1441 ctgattttgg gaaatactta tcaacagtat ctgcatcttg tgtttttatt gaattaaaca
     1501 tactatccac ttcatttttt atcttattat cattagtaca accagctaac accagtactg
     1561 atattgcaaa cattataata catagaataa atttcttcat taaattatat ccccctatac
     1621 ttttttgcac aaatattatt ctctttttta tcttttgaaa aagttgtagt aattgcattt
     1681 tgtggacaaa cttttataca ttcaccacac ctaatacagt ctggactatt tacatcttta
     1741 tatattggta tatcaagctt acattttgtt tgacatgctg tacaatttgt acatttatct
     1801 ttatcaattt taaatctata tattgaaata ggattaaaaa aaccatagat tgctcctaaa
     1861 gggcatatat acttgcaaaa tggcctataa gtaatgattg acatcaataa tatcaatagc
     1921 aaaatactta acttccagct aaataaaaat cctattgatt ctcttaaatt ctcatttcct
     1981 aaaataagtg gtattcctcc caaaagtgtt cctgaagggc aaatccattt acaaaaccaa
     2041 ggatttccac cccctgctac atttacaata gcaactggca aaataattac aaacattatt
     2101 aagactatat actttagata ttttagatat ttatcaccat aaactttttt tatctttact
     2161 ggaaagggta ctttatgtag taaatcttgt acaagtccaa agggacaaag ccaaccacaa
     2221 acaaatctgc caaaaaaagc accaaatgcc attaaaaaac caacaacata aaatgagaat
     2281 ttatactctc tgcttgataa aactgcttgt aatgaaccta ttggacatgc tccaagtgca
     2341 cctggacatg aataacaatt caatccaggt acacataatt ttttactttc tcctccatat
     2401 atagttcctt ctaaaaatcc atttacatat ccatttgtta atgctgtaaa tgcaacttga
     2461 ataataagtc ttatattatt atttacctta gataataact tcattcctct tctcctaacc
     2521 aataccaata cactcaagac aaatcataat tgctttagtt aatactgtat ttgtttctcc
     2581 acgatatgta cctaatgcaa taaatataat actaattgca ataatagaaa tgcctttttt
     2641 attatcttta ataaagttac tcattggctt ttaccatttt tagtctttca tctataattt
     2701 ttttccactc ttccttacta tttgcaccta caaccttctc acccacaaag tttcctttct
     2761 tgtctacaaa ataagttgtt ggaaactcca taactctttt aaaatcagtt tttttaagtt
     2821 cttcagatac agtcaattgt tggtaagttg catctgactt tttcataatg tttttaacta
     2881 aatttttctc ttcatttgaa agaccagttc tcatatcagt tttatcaact tctacaacta
     2941 atccctttat agctacattg gaattattac tctcatattc ttttgataat gcttcaagct
     3001 ctggcatttc acccacacat ggtccacacc aagtagtcca gacattaata agagtaagtt
     3061 ctttatttga aaatatctct tttgttacct tatttccatc aacatcctcc gtatctaaat
     3121 tactaaacca ttcactatta ctcttgtttt tttctactgg cttagattct tttttgctac
     3181 atccagaaat cacacctaaa acaaaaatac atcctaaaac taccataaaa aactttttca
     3241 tatctcacac tcctagaatt tatatagtat ataaaatggc tgcttgaaat aaaaataact
     3301 tctcttctat attaaaacat tatatttaat aaataagaac taatttaaaa taagttgtat
     3361 aaaagatata tagttaaaat ctatttcttt tcagacaaaa tcttatatat atataataac
     3421 ttataaagct taagattata tacatatatt tctaaaaatt ttcttaagaa acagttattc
     3481 cttactaatg caatatacct atttttacta atataagttt attaattagc attatactaa
     3541 tttatcttaa tatgattttt tgttgatttt aagctgttta tcgtataaat aaaatttttc
     3601 ttgacatata gttactatat agcttattat agatagagag taataaaagg aggtaaaatt
     3661 tatggaaaat ttatttacaa gaaaattcac tacttttgaa tttctaaaat ttgtttctcc
     3721 tgcaattata tccatgatat ttatatcttt gtacacaata atagatggca tctttgtatc
     3781 aacattagtt ggttccgatg ctcttgctag tataaatatt gtactaccta taattaacct
     3841 tgtttgtgga tttggaataa tgatggcaac gggtggaggt gctatcgttt ctatacgtat
     3901 gggtgaaaat agacaggatg aagccaactc tacattttct tttatagttt tgttttcatt
     3961 gattgttggg atttcattca cagtaatctc atatttcttt atcaaagaaa tatctatttt
     4021 gcttggtgca acagataagt tattaccata ttgtataact tatggtaaag ttatgatttt
     4081 atgtacacca ttttatattt taaaatttat atttaactac tttgcaagaa ctgatggaaa
     4141 ttctaaattt agtttatttc tatcagtcat tggtggtgta acaaatataa tattggatta
     4201 tgtatttatt aaatattttg gaatgggtct tttaggagct gcagttgcaa ctgctatagg
     4261 tattatttta acttgtgttt taggtattat ttacttctta tctaataaat ctacactcaa
     4321 attaagaaaa ccaaaaaccg attttagact tataagagat actatgataa acggttcttc
     4381 tgaaatggtt acagaattat ctacaggaat tacaacattc ttatttaatg tagtagcttt
     4441 aaaattagca ggagaaaatg gacttgctgc tcttactata gtattgtatg ctcatttttt
     4501 aatgacatca gtctatctag gattcgctgc tggagtgtct ccattaataa gctataattt
     4561 tggtgctgaa aacagtgata aattaaaaga aacatttaaa cattctctaa aatttatatt
     4621 tgtttcttct cttttagtgt ttattattgc tttagtattt gcaccattta ttgttagggt
     4681 ttttgtaagt ccagataaca cagtatttaa actagcctta caaggattaa aaatatttgc
     4741 atttgctttt ttgtttgttg gtataaatat atttgcatca ggatttttta cagcatttca
     4801 caatggaaaa atttcagcta ttatatcttt tagtcgtgcc tttgttttta taatcatagg
     4861 aatcataatt cttcctccta tgttaaacat gactggatta tggcttacag ttccatttgc
     4921 tgaggttata accatattta tatctattct atttataaaa aaatataaag gtagatataa
     4981 gtattaaaaa ttaatgctta aaatcaacat ttattaaaac taataaacct gctttaaaat
     5041 acaaatttac aaatttgatt tttaagcagg ttttatttta gttataataa gtcatttgca
     5101 tactctttaa ttggtgcttt tctaagtaat aaaattataa atattatgca aataactata
     5161 attcctacct ttgttccaaa taaaataaaa ggattctgaa atgaataaat aattttttct
     5221 aaatacaata gcattttatg catattttta gttgcaaaat taactatata aattaccatt
     5281 aatatcggta atcctatcaa tatagtaata ctagtaactt ttctaactct atatgtaaaa
     5341 gctccaagta atactcctat aaaacctata catatttcat ttatacatat ttgtacaaaa
     5401 taatttaaat aagttagtgg catacttgat gttgaaggat ctatcagtgc tgatatagat
     5461 gtccaaatca tatctctctt tagtaaaact gatagttcta tactgtaacc tgttataatt
     5521 tctataaata acttcgataa aaaaatcaaa actataccta aaatagaaat cacaaagctt
     5581 aaaataatta aatctatgac aatagctttt atacaacttt ttcgatctgc tcttatactt
     5641 aaagctcctg aaaagtcttt atttgctata tttactccat acacaaatag cagtatagtt
     5701 atatatgtta aaataggatt cacaatcgtg gataaattag ttttagatgc ttctccaaaa
     5761 atcttgagga taaacactgg caaaatattc ataacaattc ccacaatcat aaatataatt
     5821 atatacaatt tagtattttt attaaaaaat tttatatatg gctttaattc attcaattac
     5881 aattcctcct tcttagtcat gttaacaaac atatcttgta gccctatgta tcctacatca
     5941 atatttgaat ttttaagtat tttttcatca ttttcactaa aatcaccata gtaaaaataa
     6001 gcaactgcat ttccaaatgc ctttttaggt tttatatttt ttatacattc taatttttct
     6061 aactcttctt tatttccagt aatataatga gctttttgtt ttatgacatc aatttcttca
     6121 tctataataa tttttccctc atttaatatt attacatgct ccagtaaatc atctatttca
     6181 tcaatcaaat gagttgatat tattattgtc cttggatttt ttatataact atctaaaatt
     6241 atgttataaa actcttgtct atttactgca tccaaaccaa ttgttggctc atcaaatatg
     6301 gtgatagctg aattagaaca aatacctatt atatttgaaa gtatagtttt catacctctt
     6361 gacagttgtt tatacttttt tttagtattt aaatcaaaat atttgcataa ttcttcttct
     6421 aagcctttat cataactttt ataaaaacta gaagaaaatt caaatatctg acctacttta
     6481 aaatctggac tataaaattc tttttccctg acgatacaaa cttcttccaa aacttttata
     6541 tcttcttttg ggttctttcc taatatttct atctcacctt cattttgaat taactgattt
     6601 accattatat ttaataatgt tgtttttcca gctccattct tacctaataa accatatatc
     6661 ttattttttt caaagtttag agacatatta ttaaaaatat tttgcttctt aaaactgtga
     6721 gataaatttt ctatcttaat agaactcctc atatattaat cctccttgaa attaattata
     6781 atatcaacca attcttctct atttatttct aatttgttag cttcttgaag taggtttttt
     6841 acaaaattat gtttaaaatt ttcttttcta gcttctttta taatagtttt tgcaccatct
     6901 gatacaaaca tccctatccc cctcttctta tataaaatat ttttatcaac caatatattt
     6961 atacctttta atactgtagc tggattaatt ttataaagct ttgaaagctc tgttgttgat
     7021 ggaacctgtt cttcttcttt tattccattt gatagtatct catcttcaat tgctcgtgct
     7081 atctgaataa atataggttc ttcattattt aatactaatt tcataggttc ctcctttctc
     7141 cattagttag ttactcaact aattaactat ataacttata atatcttgaa aaatattttc
     7201 tgtcaatact aaataaaaaa cagagggaaa attccctctg ttttttgttc tttatattta
     7261 taattaaatt ttgatttttg taatcctatc ccataagtta aaaactttaa taatctgttg
     7321 tatcttcatt ttttaatatt ttacatattg agctagttcc taacctttct gctcctgcct
     7381 ctataaattt ttctgcatca gaaattgatt taactccccc tgcagctttt atttttacat
     7441 tttttccaac atgctctttc ataagcttta tgtcttctaa agtagctcca cctgttccca
     7501 ttccagtaga tgtttttata aaatctgaac ctgacattgt tactatttca cacattttta
     7561 ttttttcatc ttcatctaaa taacatgtct ctataatgac ttttaatact ttatctccta
     7621 tagctttttt tatttctttt atttcttttc ctatattatc ataatcttta ttttttatat
     7681 ctgaaatgtt tacaaccata tcaacttcat ctgctccatt ttcaatagca tcttttgctt
     7741 caaatacttt tgtagcagta gtttgatatc ccaaagggaa ccctatcact gtacatatct
     7801 ttattttacc ttttagatat tctgatgctc ttttcacata tgatggtggt atgcaaactg
     7861 atgctacact catatctaca gcttcatcac ataaaatttt aatatcttcc catgtagttg
     7921 tagcttttaa aatagtatgg tctactgttt ttaatatatg tttcataaaa tcctcctaaa
     7981 tttataatta atataattag attacttttt taaatgcaat tttctctttg caatattcag
     8041 tatcatatca acctcttcaa ctttaaaaat agtcattagt agtgtataaa ttccacctcc
     8101 aactataact gaaatagcta gtgatacaaa ctcattaaat gttcctactc ccaaaattcc
     8161 aaatataaat ttatacgtaa agtatgataa aacacccata attaaagatg caactaccga
     8221 tttcaaagtt gcttttatta ttttatcttg tccaaaatat ccaacttttc tctttaggtt
     8281 caagaagagt aacaatatac atgcaattga tgatgaacta gttgcaagag caagaccacc
     8341 atgagccatt ggttttatta aaactaagtc caatactata tttaccccta cagatataat
     8401 cccatttacc ataggtgttt ttgtgtcttg taatgaataa aaaacctttc ccaaaatatc
     8461 tcttaatcca aatgcagtca taccaactgc ataaaaaatt aaggcagttg ctgtcatttg
     8521 ggttgccctc gcatcaaaag cacctctttc aaaaatgatt ctaacaacag gagttgcaaa
     8581 aaaaatagaa gcaactgaaa taggaatcat agaaattatt atcatattta tactagattt
     8641 aactgaacta gtaaacttct tttgattatt ttctgcactt aacttagata acataggata
     8701 cataacagat actattgaag ctgtaaatgt ccctgtaaca aaaccattta atctatctga
     8761 ataagtaagt gctggaatgc ttcctttaac taatgttgag gctaaagttg tatctaccaa
     8821 tgagttcact tgattaacag caacacctat aaatactggt gaaagtaatg ctagtaattt
     8881 aataaggcta tcatctttaa agtttaagta gtataagtat ttgtagttcg tttttttaac
     8941 aaaaaacatg taaaagagca gttgaactac catagcaacc acagcaccaa ttggaagtat
     9001 gtatggtcca aatacggtac ttaacattat tgaaataatt attactatat tatagggtat
     9061 actcccaaat ccaactacaa taaagttctc tttaatttgc agaaatgctg acataacact
     9121 cgtaatacct atgaatatta ttcctgttat caatatttta gtaaatttta cggtaagtaa
     9181 aaacctctct ccttcaaatc ctatagcaaa tatacttaca agttgctttg agaaaataac
     9241 tcctaatata gctacaacta tgcatatacc aactattata tttaaaacat tgtttaaaaa
     9301 ctttagtgct tgcttttcac cttgtttact acttatatct tgatacattg gaataaaagt
     9361 agtaactata gcagtaccta ttgctgcaaa tataatattt ggtatattca tagctgttaa
     9421 ataactctct gtatataagc ctgtaccata aattgatgat aatactaatt ctctacccat
     9481 tccaagaatc ttagagatta tagtaactat catcaaataa aaagttgctt tagctacctt
     9541 gctcatttta tcactccact tctaacatac ctctttttaa tcaagtaaaa tttggctcat
     9601 tagatataat tctatcaact aatttgcctt gcttagccct atcaaaatat aattaacacc
     9661 tatttcttaa tatatcacaa actacattat tcttcatatt tttttatttc tccaataagt
     9721 tttacatctt tcctatataa attgtatagc ttcaattata ttcaaagaaa tggagttgct
     9781 acccgataac tttaaaagta aaaaacagat tttattatct ttttaaacta tattctaaca
     9841 tattttgtcc atattgagaa attttactaa actattatgt actttattaa ataaataaaa
     9901 taacagcaca cctataaaat acaagtgtgc tgttcataaa cagattttat aaaaaaataa
     9961 ttcctaagta gagattaaca tgctttctca tactctcata tataatgtgt ctaaaaatat
    10021 taataaaaat gctttaattg ttttaactta cttggatgtc ttaattttct tattgcttta
    10081 gcttctatct gtcttattcg ttctctggta actccaaata cctttccaat ctgttctagt
    10141 gttttagggt catcatcatc aattccaaat ctcattctta aaacttgctg ttcttgctca
    10201 ccaagacctg taagtagttc ttctatcttt tcttttaaat tatgctgttc aacttcgtgt
    10261 attacaacat ctttaaaatc agcatctgat ggtataaatt caactaaact actatcctca
    10321 tcttctttta atggagtatc caaagataca acatttttat ctcttcttaa taattccaac
    10381 actttgtcaa cttctaagcc acatgcatct gcaatctcat ctatagttgg ctctcttaat
    10441 aatacattta aaagttcttg tttctttttc tttacaaaat ttattctctg atgaagatgt
    10501 ataggtatcc taatagtatt ttcgcaatcg tcgatatatc ttgttatact ttgttttatc
    10561 caccaagttg cataagtgct aaatttgtat ccttttttat aatcgtactt ttctacagct
    10621 tttataagtc ctatatttcc tgcttgaatt aaatccaaca tatcaatact atctctttta
    10681 tatctctttg ctatgctcac taccaaccta taatttgaat ttataaattt ttcttttgct
    10741 actgaagatg agttgattat ttccttagcc agctctacct cttctcctgc tgacaacatt
    10801 ttgtattcct ctatttcctt taaatacatt ttcatcgcat ttgatacatt tgatgaaccc
    10861 acacaaatat aattttcata attattttct tttttagtat ccataatcaa accccttcta
    10921 ttcatagaat ttgctaaaac aaaaataaat aatttaaacc tacataatct acaattacat
    10981 aatatcccat tctttaaatg aattgttttg tatattatgt atacaaattt ataaaaacta
    11041 tacctataat attattctac ttctaaccgc aatatcctcc ttatatatat aatttatttt
    11101 attatatgtt gttatattct tagttttttg aatgatatat gtctaaaaaa agactgttta
    11161 ctaaacagtc tttttttata tatatgctca atatttaatt ttcatgatga tgattacatc
    11221 cacatccaca atttttatca tggtgatgat gttcttctaa atcttttgcc tgttgttcca
    11281 tttcatgaaa ctcttttacc attatatcat aagttggaag agctgcctca gtatcgtatt
    11341 cttcccctct ccaatcagcg tacatcatag catccccatt agttaaaacc aatctacctg
    11401 acatagttat attatccact tcttctaaaa attctatttg tttttgtaaa acttctcctt
    11461 ctaactctac atcttcatct aaacattgca ctatcattac aggtgcataa taatcttctt
    11521 catctttaac atttacaaca atatctaaaa ctccttctgc accttcttca aattctgcca
    11581 actcaacatt tgtatcaatc atatcttgag ggactaataa atcttctatt aaatatttta
    11641 ttactctatc ttttactaat tcttttgaca tttatttttc tccttccgat tctataacat
    11701 tatcataatc atttctatat tatagtatac tacattaatt gttttttcaa tctcttacaa
    11761 aaattatttt tttattatct tccttatatt ccctttttta ttacaaagtt gtaatcgcat
    11821 tgatttaaaa aatagtttat atttagtata atagaaatgt agcacatatt tttattcaat
    11881 atattaataa aaaaatagat tgaaaatgta atgtatgtta aatctaggag gaatattatg
    11941 aagtttaaaa aacaaattag ttctattgtt gtgtctacta tgcttgtact tgggagtatg
    12001 aacctttctt atgcagatgg tacaaatgta gttacacttg gagctaactt atcagagtct
    12061 caaaagcagc aaatgcttaa ttactttgga gtaaaaaaag accaagtctt agttttagat
    12121 gtaacaaatg cagaagaaag acagtattta caaggtgttg caacagaggg tcaacttgga
    12181 aaagttacta tctcttgctc atacgttgaa cctactaaaa aaggaaatgg aattaatgtt
    12241 aaaacagcaa acttaacttg ggtaactagt tcaatgattg cttcaaccct tacaacagct
    12301 ggtcttgaag atgcaaatgt tattgctgct gctccatatc ctgtaagtgg tactggagca
    12361 ttgacaggaa tcatgaaagc atttgaggat gcttcaggaa agaaacttga tgaaactaag
    12421 aaagaaattg cttctgaaga attggtagtt acaggtgact taggagatga tatagggcaa
    12481 gaaaaagcaa caggtgtaat gaatgatata aaaacagaaa ttgtaaagaa tggtacaaaa
    12541 gataccaatc aaatagcaaa tacaataaat aatgttgtaa ataattacaa tattactatt
    12601 acaccagaac aaaaagaaca aattaaaggt gtaatgaaaa aaatagctga ccaaaattat
    12661 gattacaata gcatgaaaaa tacactagat aatgtatcag ataatgtaaa tgaacaatta
    12721 aagaaattag gtgaaagtgt taagggttct ggtatactag atactattgg tggatggttt
    12781 agtggaatag gagactggtt ctctggttta ttctcaggcg gagataaaaa agatttggga
    12841 atcttaaata acactaatga tgagtctctt ggctctgatg ctgtaataaa ttctacagaa
    12901 ggtgttcaaa taaatccaca aaataatact aattctaaca atgatagtga tacaaatagc
    12961 tcaaaaaatg atacttcaag taataatgaa aataacgata gttctcaaac aaatgaaaac
    13021 aacacaacaa ataattcaga aaatcaatca aataataatg actcagttgg tttctttgaa
    13081 aaaataaaaa attggctttc aggcttattt tagaaattaa acaaataaaa agaattgcct
    13141 aaaatggaaa ttttctataa aaggcaattc tctttattta caataaattt ttattactca
    13201 ctcatttttt tagatttttc tatacatgca catattgctt ttatcacaga agctctaaaa
    13261 ccttcttctt caagtacttt aactgcttct atagtagttc caccaggtga acataccata
    13321 tcttttaatt caccaggatg ttttcctgtc tcaagtacca tttttgcaga acccataaca
    13381 gcctgtgatg caaacttata tgcttgtggt cttggcattc ctgcaattac tgctgcatct
    13441 gctatagctt ctataaataa aaatacatat gctggtgcag aaccacttgc accaattaca
    13501 gcttctataa gatactctgg tactacctca gtatttccaa aagaattaaa tacttctgta
    13561 actgcttcta agtcttcatt gtttatattt ttatttatag aaagagaaga catggcttca
    13621 tttacaagag ctggagtatt tggcatagtt ctaactattt ttttatcttc tcctataatt
    13681 gactctatat cctttataga ttttcctgct gctattgtaa ctataatttt attgtcatct
    13741 ataaagtctt ttatctcttc caaaatatca tcatatatat ctggtttaac agctacaatt
    13801 actatatcag aggttctagt tacttccttc gagtcttttg tagtatttat tccaaaattt
    13861 gcatctattc tatcgagagt tccttgacta tatgctgatg ctataaccat attaggttca
    13921 actaattttg aatttactat tccccctatc atagcgcttg ccatatttcc tgcacctatg
    13981 aatccaattt ttttcacttt agtacctcct tattgactaa tagtaatcgt taaaatttaa
    14041 gcttctttaa ctgcatcaga cttttcaaat ggatttggta tacttactac caaaattttc
    14101 actaccttat tagtatagtt gacccaatta tgattgttct tttcactatt atagtgtatt
    14161 gtgtctcctg gatacatttc tatttgttca tctcccaaaa acactgtaag agtaccctct
    14221 aatacataca caaattcctc accttcatgt acgtaacaac aaatttcctc actactctta
    14281 cttggaagaa tttcaattaa tcttggtagc attgtttttt cctttaaact agatgataaa
    14341 tgataatgta taaatgttga gttttctaca tcaaatactt ctttttcata acttcttaat
    14401 acagctcttt tatgctcttt tggcttcata aaaaagtaag ttaattctac atctagtaca
    14461 cttgctattt ttcctaagga atctgttgcc acacttgtta atcctctttc aagttgtgat
    14521 aaaaaaccaa ttgacaagtt tgttttttca ctcatatcct tcagcgtcat ttgcttttga
    14581 gttctgagtt gctttatttt tgctcctatg tccttattca aaaccatcac ccctaaataa
    14641 ttttaatttt ttcataatat aaatacaaaa atataaatat aggtactgaa cctatcttta
    14701 tttcatttaa aaaaaatttt tataagtatt actataattt atcaatcttt ttttgtctac
    14761 atttttacga ttatttacga tttatttttc acatatgtat atttaatctt gccaactaaa
    14821 gatacatttt ttataagcat ttactcttta tataataaaa cttaagttgt tcatgtagtc
    14881 ttcttctggt ttaattatta aaatttcaaa ttatattatt atttctacac attattacat
    14941 cctttagtac aattataaca taattttaca atttaatgat atctattcaa tgtctttttt
    15001 tactctacaa catattttat tttagagttt aatactatat atatttttta tatacagcct
    15061 tgtcattttt tagattgtca agagttattg aagtatttta tgtagattta tattttattt
    15121 tctaatttct catttaacaa gaattgctta tgataaaaaa taatatcatc tcaataagat
    15181 tcttgtaaat atatctatat tctaaatata atttcttttt ttgtcaaaat ttcttcattc
    15241 tttaataa
//
LOCUS       DAEQJM010000080        14699 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.081, whole genome shotgun sequence.
ACCESSION   DAEQJM010000080 DAEQJM010000000
VERSION     DAEQJM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14699
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.081"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(214..420)
                     /locus_tag="KRQ43_003130"
     CDS             complement(214..420)
                     /locus_tag="KRQ43_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743472.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(468..893)
                     /locus_tag="KRQ43_003131"
     CDS             complement(468..893)
                     /locus_tag="KRQ43_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743473.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            1065..1292
                     /gene="acpP"
                     /locus_tag="KRQ43_003132"
     CDS             1065..1292
                     /gene="acpP"
                     /locus_tag="KRQ43_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH2743474.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(1436..2440)
                     /locus_tag="KRQ43_003133"
     CDS             complement(1436..2440)
                     /locus_tag="KRQ43_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBH2743475.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(2454..3356)
                     /locus_tag="KRQ43_003134"
     CDS             complement(2454..3356)
                     /locus_tag="KRQ43_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH2743476.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKKEK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(3551..4726)
                     /locus_tag="KRQ43_003135"
     CDS             complement(3551..4726)
                     /locus_tag="KRQ43_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH2743477.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(4813..5658)
                     /locus_tag="KRQ43_003136"
     CDS             complement(4813..5658)
                     /locus_tag="KRQ43_003136"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HBH2743478.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(5756..6553)
                     /locus_tag="KRQ43_003137"
     CDS             complement(5756..6553)
                     /locus_tag="KRQ43_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH2743479.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(6572..7582)
                     /locus_tag="KRQ43_003138"
     CDS             complement(6572..7582)
                     /locus_tag="KRQ43_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH2743480.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(7601..8383)
                     /locus_tag="KRQ43_003139"
     CDS             complement(7601..8383)
                     /locus_tag="KRQ43_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH2743481.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(8442..9578)
                     /locus_tag="KRQ43_003140"
     CDS             complement(8442..9578)
                     /locus_tag="KRQ43_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBH2743482.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLKPLASGDKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(10286..10753)
                     /locus_tag="KRQ43_003141"
     CDS             complement(10286..10753)
                     /locus_tag="KRQ43_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HBH2743483.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKSEKWVDVCKNW"
     gene            complement(10832..11374)
                     /locus_tag="KRQ43_003142"
     CDS             complement(10832..11374)
                     /locus_tag="KRQ43_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743484.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDIGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITESTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(11426..12112)
                     /locus_tag="KRQ43_003143"
     CDS             complement(11426..12112)
                     /locus_tag="KRQ43_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH2743485.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            complement(12100..12972)
                     /locus_tag="KRQ43_003144"
     CDS             complement(12100..12972)
                     /locus_tag="KRQ43_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743486.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDREKFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVRGCSI"
     gene            13107..13907
                     /locus_tag="KRQ43_003145"
     CDS             13107..13907
                     /locus_tag="KRQ43_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HBH2743487.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            13932..14501
                     /gene="yfcE"
                     /locus_tag="KRQ43_003146"
     CDS             13932..14501
                     /gene="yfcE"
                     /locus_tag="KRQ43_003146"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBH2743488.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
BASE COUNT         4698 a         2627 c         1609 g         5765 t
ORIGIN      
        1 catccttctt ctccaaagaa tctatctaac attgtacgtt acctcctgtt gatattttgt
       61 tgagcttttc gctcctaaca tatactatgc atttggtttc cattttgcta atgtattttt
      121 actatttttt taaatttttt aatttgaact aaaaaaggta aaaccataac ttgtataagt
      181 tactggtttt acctatttaa taatcaatat tttttagcaa caacaaccat catcgaagtt
      241 aaataataac aatactatta atataaccca tatccatata ttgtcatcgc ataataagtc
      301 ttctaaaatg tctgtgcata atagtaagaa tactataact attattatca acattttatt
      361 accaaaaaat ccttcgcatc ctccaaagaa acgttccata ttgtcttcta attttgtcat
      421 aactaatcct ccttgaatca ttaagagact aagttttgtc tctttaatta aatatatgta
      481 gtaatagaca gataagttac ttctaaaaag tttttattga ttagtttatt tatttctttt
      541 tcaccaagtt tattgtatct atcaacttca tccagataat cttttttctc ctctgatata
      601 gtgtagatta aactttctat tgattttatt ttgtactcct tatatctttc tatcaagaag
      661 gatgtttttg aattttctat tcctttcttt acatgcatta accttgatat gtagtcttct
      721 ttttcattag atacataact ctccttttca gctacatctt caaggattaa attggtctcc
      781 attacataat cctctatacg ttgcatatct aaagttattg aattataata aaaatttact
      841 gctataagta aaaacattcc tactgaagtt agtaatagtc ctacatattt catagcattt
      901 cctcctaagt tatatttgtt atcaataaag tttattcatc aaataatact ttattactac
      961 atttataaaa ttttattatt ttttatagat tccatattga aaaattcttg atattatatt
     1021 aaactaacat taaaattaat taaaactgct ttaggaggct taaaatgttt gagaaaataa
     1081 aagaaataat agcagaacaa ttaggggtag acaatttaga tgagataact atggaagcat
     1141 ctttaatgga cgacttagaa gctgattcat tagatgctgt tgaaattata atggcccttg
     1201 aagatgaatt tggaatagaa ataccagacg aggaagctga gaactttaaa tgtattggtg
     1261 atatatgtaa atatatcgaa gaaaacaaat agtatcgttt tgtctacaaa tataaatagt
     1321 ctgtgtaaac ttctacataa taaattatat tagagttcgc acagactaga ttacatttat
     1381 ttacaatata taaaatacac gctcttatat ttaatttata tactaagtat ataaattact
     1441 tttcttcata aaatgtaaca ttctttatta ttatatctat agttccatct tgattttgct
     1501 ttacagtata cttcattggg tcttcaaaat cagttagatt cccttttatg tcaaaaccat
     1561 tatccgtttt tatacttctt tttttaagct ttttctcaac ccatttttta tctatactaa
     1621 aactttcatc aagacctttt tcttccatat gctctttaaa gctatccttt aactcatcat
     1681 ctttaattga attatcaaca aagtcattta tatcaacttc atgtttttcc ttcagtgtat
     1741 aatttaatat acttcttaca tcttcagctt gctttatatc attactaaga gcattagtta
     1801 tccaattttc agctgtattt ttaaatacct tggtcttgta cttatcatca tctatttttt
     1861 tagcatttaa aaattctgtt acaaacttag attctgaccc ttctttttca gcatccttat
     1921 ctaaaagcct tagatgaaac tcatcattta taccacttaa actaatcaaa gctccttgct
     1981 tttgtcttaa agtctctggg ataccaattt catttgaaac catttgaata ttaaatttat
     2041 catccacaaa ttcaattgaa tgagtgtaca actttttata atctaatttc agtattgcta
     2101 cactcttttc atctttaata gtgtataagc aaattgccaa atcacaagat tctagtgcag
     2161 cattaatttt cataacgtca aacaagtaag atgcaatttc tttagaattt ttcaaaaaag
     2221 tactttcatc atatattatt tgttcacaac agtttttaat taaattgtca ttataatctt
     2281 taaaaacacc ttttcttaaa tcctcatctt ttgcaattct ttttatagct ttctggaaaa
     2341 aaccatctac ttcttgatta actttgcctt caaagtcatt taatattgga acatcactat
     2401 ttttgtccaa aacatgtatt ataaatttat gtattatcat atatatcacc ccattatctt
     2461 aatttcgata ttaactcttt catatcctct ggtatatctg ctttaaattt caatttttct
     2521 tttgttcttg gttgttcaaa ctctagcttg tatgcatgaa gtgcttgcct atttattagc
     2581 tcttcatcta cataaccata caactcatca cctattattc catgacctat atgagccata
     2641 tgtactctta tttgatgtgt tctaccagtt tctaagctta cttctaatac agttgcattt
     2701 tctagtcttt ctattacttt atagtgagta acagatgact gtcctctttc atctattatc
     2761 ctctttattg aatcttctgt aggtctataa attggctcat ctatagttcc ctcattttct
     2821 tttataattc catcaactac tgttatatac tttttttcaa ctttattttc actcattgct
     2881 gtagataaag tatgatgtgc ataagcattt tttgctacta taactaaccc tgaagtattc
     2941 atatctaacc tatttacaaa tcttattttt acgttttctt tttgattatc tatatagtaa
     3001 ctaataccat ttgctattgt tttatcatag tggctttttg ttgggtgaac taccataaat
     3061 ggaggtttat tcaccataat tatatcaaaa tcatcataaa ttatctgtaa atttaaatct
     3121 tgaggttcaa aatttgcttt ttcctcgtct atttttactt ctattaaatc accactatac
     3181 acctttaaac ttggtttttt atatactcca tttactaaaa cactcttttc cttcttcatt
     3241 tttgataatg acctaactga gaaatttagc ttgtccaata aaacttcttt taaagtcatt
     3301 tcttcttcat ttgtatacga tataagatta tatctttgat tctctttttt aaacaaactt
     3361 ttacctactt tcttttatat cttcctgctt tttatatctt caaaatcatg atattatata
     3421 ttttacacta tttttgttta atagataata attattttta actataaaaa cctgtaagaa
     3481 taacaaatag ttattcatac aggttaaatt cataattaaa tatttaattt gtaaatatta
     3541 taatctaaaa ctatctctta actattaaag tagttcccat tccaccacct atacaaagtg
     3601 tagcaagacc agttttagca tctcttctct tcatttcata taaaagtgta gtaagtattc
     3661 ttgctcctga gcatcctatt ggatgtccta tagctattgc tccaccatta acattaactt
     3721 tattcatatc tatatttaag tctcttatta cagctacaga ttgggcagca aatgcctcat
     3781 tagcttcaac taaatctata tcttcaatag tcatattagc agcttctaaa gcttttttag
     3841 ttgctggaac tggtccatat cccattattt tagggtcaac accagctgtt ccataagaaa
     3901 ctatagttgc aagaggctct attcctagtt cttcagcttt ttctttagcc attactacta
     3961 gcatagcagc accatcattt attcctgatg cattaccagc agtaactgtt ccatcttttt
     4021 taaatgcagg tcttaactta gcaagttttt ccattgtagt gccaggctta atatattcat
     4081 ctttatctac tacagtgtca ccttttcttc cttttataac aacaggaact atttcttcat
     4141 caaattttcc ttcagcttga gctttttcag ctttattttg acttgcaaga gctaattcat
     4201 cttgttcttc tctagttata ttccattgct ctgctatgtt ttcagcagta atacccatgt
     4261 gatagttatt aaatatgtct gataatccat cttttatcat tgaatcaaca aaagcagcat
     4321 cacccattct tgcaccatat ctcgcacttg gtactaaata aggagacata ctcatatttt
     4381 cagctccacc aactaacatt atatcagcat cacctaatgc tataagttga gatgccattg
     4441 aaacagatct taatccagaa ccacaaacta tatttatagt catagctggt ttttctactg
     4501 gtattcctgc tcctaatgct atttgtcttg ctatattttg tccaagacct gctgtaagta
     4561 ctccccctaa aagagattca tctatcatat ctggagttat gttagctctt tttatagctt
     4621 ctttagctgc tgttacccct aactctaccg ctgaaactga tttaaatgct cctccaaaac
     4681 ttcctactgc tgttctagct gcactggcaa ttactacttc tctcatattc attaccccca
     4741 ttaaattaga tttttcatat atccgaaatt gttttttaaa caattttatt taaactttta
     4801 attcccaaat tcttatttat tataatcata gaatcctatc ttagtttttc ttcctaattg
     4861 attagctcta accattttag ctaaaagtgg atgaggtcta tatttagtat ctccaaattc
     4921 agtatataaa acgttcatta tagctaaaac aacatctaat ccgattaaat cacctaatgc
     4981 tagtggtccc attggatggt ttgctcctaa tttcatagct tcatctattt cttctttact
     5041 tgcaacacca tctgcatata taccaacagc ttcatttatc ataggtataa gtattctatt
     5101 tactacaaat ccaggagatt cagatacatc tactggtact ttattgatac tcttagataa
     5161 ttcaaatact gtatcaaaag taacttttga tgttaactga ccacttataa cttcaactaa
     5221 tttcatcata ggaactggat taaagaaatg cattcctata actttatctg gtctcttagt
     5281 agaagaagct atttctgtta tagataatga tgaagtattt gttgccaaga tagtatcttc
     5341 tttacataat tcatctagta acttgaaaac atctttcttt atattcatgt cttctacaga
     5401 tgcttctatt attaaatcca tatcttttaa atcttcataa ttagtagttg aactaacatg
     5461 acttaatatt tctgcttttg tagcttcatc catttttccc ttagtaacta acttagttaa
     5521 atttttatct aataaagcta aacatttatc tatagcacct tgagttctac tctttaaaca
     5581 tacatcatgt ccacaacttg caaaagtttg tacaatacca cttcccatag ttccactacc
     5641 tattacagct aatttcatag ttataacctc ctgttatttt agtatttata ttctgttaac
     5701 tagattaaaa tactatttaa tctagttaac agcaaatata tttttaatta gatttttacc
     5761 cttttataaa gttagcttct ctcttttcaa cgaaagctga cattccttct ttttggtctt
     5821 tagttgaaaa acaaagacca aataaattag attctatatc tattccagta tttatatcag
     5881 tttgagcacc aagttgtatt gcttctttag agtatctaac tgcaagctga gcatttttag
     5941 ctattatctt agctaatttc tcaacttctt ctattaaaat gtctggctca acgactctat
     6001 ttactagccc tattttttca gcttcatcag cttttataac ttgacctgta aagattaatt
     6061 cttttgcttt tgccattcca accaatcttg taagtctttg agttcctcca tatcctggag
     6121 ttattccaag agttacttct ggctgaccaa atttagcttt agcagatgca attcttatat
     6181 cacatgccat tgcaagttca catcctccac ctaaagcaaa tccgtttaca gcagctatca
     6241 ctactttttt actattttct atttctccaa aagcttttgc tcctaagata ctaaaatctt
     6301 tagcagctac agcatctaaa tctttcatgt atgcaatatc tgctccagct acaaatgcct
     6361 ttccttcccc tgtcaatatt acaacatcaa tagtttcatc attattaata tctacaaata
     6421 cttcataaag ttcttctaaa gtctttgaat ttattgcatt aagggcttta ggtctattca
     6481 ttttcactgt acatatattt ccatctactt caacagctac attctcataa actttaacat
     6541 cacttgtact cataataccc tccccaagaa attagttagc taaaacttca cctttttctt
     6601 ttgcaacact taactgactg ataagttctg gaagcacttt atgaacatct ccaactatac
     6661 caacatcagc atatttaaat attggagctt ctggattttt atttatagca actataaact
     6721 cagcatcttc cataccagct atatgttgta ttgctccaga tataccacat gctatataaa
     6781 ggtctggtct tacagtttta ccagtttgac caacttgtct tgctttatct aaccaacctg
     6841 catctatagt ggcacgagaa ccagaaactt ctccacctat aatttcagct aattcataaa
     6901 gtatgtctaa gttttctttt ccacccattc cacgtccagc agaaactaat atcttagcat
     6961 cttctatttt aacttgtttt ttagcttctt ttattacttg tacaacttga actaatttat
     7021 cagcatcatt aaattctacc ttgaaacggt taattacagc ttctttagtt tcatcaggtt
     7081 catttttctt cataacccct ggtctaactg tagacatttg aggtctgaaa tctttacaaa
     7141 ctattgttgc cattatattt ccaccaaagg caggtcttgt cattaataat aattttgtat
     7201 cttcagctac tgcaagacct gtacagtcag cagtaagacc tgtatgtatt ctagcagaaa
     7261 ctctaggcgc taaatctcta cctattgaag ttgcaccaaa taatacaact atagggtcag
     7321 ctgcttttat tgcttcataa gctgcttttg tatatggttc agttgtatac actgctaaag
     7381 cttcatcatc tactactatt acctcatctg caccatagtg tgctaatgta tctattaaac
     7441 cttctacctt actacctaaa agtaatgcag aaacttttgt atcataatct tttgctattt
     7501 ctgtagcctt tcctagtaat tctaaagaaa cagtttgaat tacattttct ctttgttcta
     7561 ttactactaa aacgttaccc attctttatc cccccttaaa ttatatgata tacttctctt
     7621 ttaatttatc tatgataatt ccagctgatg ttttcgcatc ttcattgtat attgtaccag
     7681 ctggtttaac tgattttgta aatgatttaa atacactagt tggagaacct ttaagaccta
     7741 aattagaagg gtcaacttct atatctttta cagtccatgt ttctactaca tcattttcga
     7801 aagcatcata tattcttcca actttcatgt atcttggtgt gttcatatct ttaagagttg
     7861 ttataaggca tggcatttta acttttaagt catggcaaca atcttcaaat tgtcttttta
     7921 ctaatacata ttcaccttca gtttttattt cttcagcata tgttattgat ggaagattta
     7981 aatgttcagc tatttgaggt ccaacttgtg cagtatctcc atctatcgcc tgtcttccag
     8041 ctattataat atcaaaatct atatttttta atgctcctgc taatgctgat gaagttgccc
     8101 aagtatcagc acctgcaaat gctctatctg ttaataatat acctctatct gcacccattg
     8161 ctaaagcttc ttttaaagcc atatctgctt gaggaggtcc cattgttata acagttacat
     8221 gagcacccat ttcttctttt aattttatag cttcttctaa acctgcttta tcatcagggt
     8281 ttattatact tggtactcca tctctaatta aagtacctgt attaggatct agtttaactt
     8341 ctgttgtatc tggaacttgt tttatacaaa cgactatatt cataaatcct tcctccatat
     8401 ctattttaat atcgacctat tgtgtatatt ttaatattta tctattttaa taattttcct
     8461 gaaataacca ttctttgaac ttcactagtt ccttcatata tttcagttat cttagcatct
     8521 ctcatcattc tttctactgg atagtcacga gtgtatccat atcctccatg aagttgtaca
     8581 gctttcgtag taacttccat agctgtttca gctgcaaata attttgccat tgctgcttct
     8641 actccataag gttttcctaa gtctttattt atagctgctt gatatacaag gtgtctagcc
     8701 gcttgtactt taacttccat atcagctaat tggaattggg tattttggaa ttttgataat
     8761 ggtctaccaa attgtactct ttcttttaca tatttaacag tttcatcaag agcaccttgt
     8821 gctaaaccta aagcttgtgc tgctatacca attctaccac catcaagagt agacattgct
     8881 atcttaaatc cttgaccttc ttttccaagt aaattttctt taggtattct gcaatcctca
     8941 aatattaatt cactagtagc tgaacctctt atacccattt tcttttcttt aactccaaag
     9001 ctaaacccag gagttccttt ttcaactata aatgctgata ttcctttgtt ccccttagat
     9061 ttatcagtca ttgccattac tacatatatg tcaccagcta ttgcatttgt tataaatatt
     9121 tttgagccat taagtatgta ttcatccccg tctaaaacag cagttgtttg ttggccagac
     9181 gcatctgtac cagcattagg ctcagtaaga ccaaatgctc ctaatttatc tccacttgct
     9241 agtggtttta agaatttttg tttttgttct tcattaccat attgatatat aggccatgag
     9301 ccaagagatg tatgagctga taatataact cctgtagtac cacaaactct agacaattct
     9361 tcaactgcca ttatatatcc tacagtgtct ccaccttctc caccatattc ttttggatat
     9421 ggtataccca tcattcctgc ttttgccatt ttttccactg tttcataagg aaatctttct
     9481 tcttcatcaa gttctgttgc taaaggttta acttcatttt cagcgaagct tacatatagc
     9541 tctttaagca tctgatattt tttagaattt aaatccataa tagcctcctc agtattttat
     9601 aaatatttta ttttcattta ttaattaaaa tctcggcaac atctataata aggtatttga
     9661 atatacgtcg agaaatttat aaccttaatc aaactacgct ctatatttat atgtgattat
     9721 actaaccaat tatgacatta atttaatcat aaattgttaa tttaaaatca actatactta
     9781 aaaaaaatct cgctttttgg aattttgtga aatttcaagt tagaataaga tttctttcac
     9841 actggtcaca gataaaataa tttgtttacg atatttatat tagggtatat taaacattaa
     9901 atattgtctg tacatctgtt ttttagccat gtacagaaga tttttatcgt ataaaaatta
     9961 ttttaataga gctaaataat cgtattttta tctgactatt ttttattttt aaatatctta
    10021 catctataat agtaacactc aaaggataat ttttcaataa tttctaatta tttttttaac
    10081 aatatttatt acattttttc cacttttttg tcattttttt attgtttcga aaaaaaatca
    10141 gaatttttta actttatttt ggattattag tttaaattag attttcctct tagatttata
    10201 aatatttaca caaaaaacta cctctgtata gattgtatac agaggtagtt ttttactaat
    10261 tcctactata gtttactata tttttttacc aattcttaca aacatctacc catttttcac
    10321 tcttagaaaa cttctccatt tcttcacatg taagttctat tgcagagtta ctactgccac
    10381 atgcaggaaa tactgtatca aatctcttca ttgaatcatc taaatagact tttatagaat
    10441 tttttaaacc aaatggacag actccaccaa tagcatgtcc agtaaactcc aagacttctt
    10501 ctggtgtcaa cattttagcc ttacaattaa attcagcctt atacttctta ttatcaatct
    10561 tagcatcacc agctgtcaca attaaaattg catcatctcc tattttaaat gagagtgtct
    10621 tagctattct tgctggaata accccagctg cttcagctgc aagttccaca gtagcactag
    10681 attgttcaaa ttctaatata ctgtcttcct tgccaaattg tttaaaatac tctcttacat
    10741 tacttattga cattaaatac ccctcctagt ctgaattttt ataaatttca tattattctt
    10801 aattatatct ataattgatt tatttttcaa attattccat aatattagca ttccatgtat
    10861 cattattttt tccaactact agataaagtc cttttgccat tggaatattg acaatatatt
    10921 ctcctttata ttctacactc ataccagatt cattaaagta cctataatca aaatttagtc
    10981 cttttggaat tacaaaatca acataacctt gattatttgg ttttattcca tatttcagag
    11041 tactttcagt tatagaattt ttttcattaa ataaatctac atttacatat gcagaacact
    11101 tattcattcc ctttttattt tccacacaat tttcaaactt cattttagca ctgtttaatt
    11161 tataactata tttactatta ttgcttattt taaatcttac aatagtaccg atatctctac
    11221 ttctcctgct atcaaaatca aaaacaattt cctctaaatg atttatttca taatctttga
    11281 cacttaccat atctctatat actaatttat ttatagctat gaatagtgta aaaatcccca
    11341 aaataaaaaa tgaaactttt ataaacttct tcatttttag tctccttata ttttgtgcta
    11401 ttgtgctata atattaatta aaattttaat aattaaactt attctttttt gaaatcttaa
    11461 tagaaaaata cattgatatt ataaaaatta ttattgttaa aaatgtcata ctatataaat
    11521 ttatatactt agtattagct atatcagtta cataatttga aagatatact cctccaactt
    11581 tactataatt aaaatgcttt acttgatata caatcatact aatcatcttc aaaagacttc
    11641 catatacaaa gtaaattaaa atacttacta taaaaccaca aactttcatt tttccatatc
    11701 caaacttaaa aattaaaggc agtaaaatcg tcaaaattgc taaaaatata tttacagaaa
    11761 aaaatacatc atttaaaacc atatttctaa agaacactag tgatgtcaat ttacttagta
    11821 aggacacaat tattgttaca gaaattatta gtcctacacc taataaatat tttgagtaaa
    11881 ctatatcttc tatactaact ggcatactcc ttataaaaat ccttgaatca ttttcataat
    11941 cacactcaaa tgtatttata aatatcaaat aactaacaac aatacttact gtataatatg
    12001 aaattgaatt aaggaaaaaa taaaacacaa aaaatagcaa tatgtacttt aaattacgga
    12061 taccatctga actaattcct attattaaat cttttcttat taaattgaac atcctctcac
    12121 ctcatttaca taataataca ttagttcttc tatagtagga tttttgacct tatgcttatc
    12181 aatttctatc aataggcttt ttactttcaa gctatctcca actttaacaa gtgcctcatt
    12241 ataatattta tactctttaa caccaactat actttcttta attgcttcta actctgcttt
    12301 atttgcccta attatcttat attcttgttc tattaattct ttcttaacag taaaaatctg
    12361 atttcctcta tttataaaaa caagataatc agcaatttta attaaattat cagtattatg
    12421 agtagaaatt attacactac tacttccatt tttcacaaaa tcttgtaagt actgcattat
    12481 ttcagttctt acaatcgggt ctataccagc agttggttca tccaaaatca ataacttagc
    12541 attatgacta agtgcgcttg ataacataag cttctcagat tgacctttag ataaattttc
    12601 aatatgcata ttttcttcta tgtcaaactt attaaggtat tcatcaaatt tttctctatc
    12661 aaaattctta taaaataaag aaactatttt tctaaattcc ttaaccttta aatgtggata
    12721 aaattgtaaa gaatcatata caaaaccaat attgttttta aagcttattg gagaattttc
    12781 aatagtttca ttacaaagtt caatttcacc ttcatctgca tcaataatcc ccattataat
    12841 ttttattaaa gtcgtttttc ccgaaccatt tggtcctata atcccaacaa tatccccttc
    12901 ctttaactct aagtttatat tatttaactt gaattttcct aatttttttg tgatattcct
    12961 tatgctaaac acatcttcac ctcttatgca tttttttata cccacctata catattttaa
    13021 cacattcact acaaaggtca tttataaatt tataaattaa gaattataaa actatgttat
    13081 aatacaaagt atgaagaggt gaatatatga aaagaattat aactataaat acaaaccaat
    13141 taaataagtc ccttgagact aaagaactct taactagaaa acttatcaat gctggctttg
    13201 aagtgtattc agatatttat ccagacacag agcttattat atcaattggt ggtgatggct
    13261 cttttttaag aacagttaga gatttcgatt ttcctgagat tcccataatg ggaataaata
    13321 caggtcatct ggggtttttt cctgatattt taccagataa gattgatagc tttattgaag
    13381 cttatacaaa aaaagattat attattcaag aaatgtcact tcttaatgcg gaagtatata
    13441 caactactag tggttctaat atgcttgctg taaatgaggt tgttataaga ggagacaagt
    13501 ctaggactat acacctaaat ttaagccttg ataataaaca tatacaaaat tttagtggag
    13561 atggtatgat tatttctact tccacaggtt caacagccta taactattct gctggaggta
    13621 gtattgttga tataaatctt gaacttatgc agattacacc tttacatccg ataaatacca
    13681 atgcatatag gtgctttaca tcaagtataa tatgttcaaa tgaatctgtt ataaagattg
    13741 caccagaata tagatttgaa gattctgtat tgattgtcgt tgatggagtt gagcacagat
    13801 ttagacaaat cgaaaatata aaagttagta tatctgatgc aaaaataaaa ttacttagaa
    13861 tgtcaaacta tgagttttgg catagagtat ctgaaaaatt tttatagact gtacttagga
    13921 ggatttttaa tatgaaaata ggaataatga gtgatactca tggtagctta ctttactttg
    13981 aaaaagcgtt aaatgtatta tctgattgtg atgttttatt acatggtgga gatgtcttat
    14041 atcatggacc tagaaatgat attccagaag gatataatcc taaaaaattt attgagacat
    14101 taaataaatt agaaaacatt gtgattgtaa aagggaactg tgatgcagat gttgaccaga
    14161 tggttataga acatcctatt cagagtcctt atgtcatgag ccaatttggt gaaattagaa
    14221 ttatattgaa tcatggttat atagaatcag aagaagaaat tattgacaaa gcaaagaaaa
    14281 tgggtggtga catattagtt ttaggacata ctcatgtaaa aaaactatac atggatgata
    14341 atttaatagt aataaatcca ggaagtactt ctatcccaaa agatggaagc cattctgtcg
    14401 caattataga tatcataaaa actgatgatg aggatgagct tgaacttgat ataaacttaa
    14461 ttgacatcaa tactggaaat ataataaata tcaatgatta gtaaattttt aataaaaata
    14521 aaataagctt taatttatta aactcataat aaaaacaagt aaaccatttt atttctatct
    14581 caattagaag tttaagtaca ataccttaaa cttctaatta aatagaatct ggtttacttg
    14641 ttttattata tgctatattg aaatataact tagtttactt gtttctatta tatattata
//
LOCUS       DAEQJM010000081        14648 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.082, whole genome shotgun sequence.
ACCESSION   DAEQJM010000081 DAEQJM010000000
VERSION     DAEQJM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14648
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.082"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            230..1141
                     /locus_tag="KRQ43_003147"
     CDS             230..1141
                     /locus_tag="KRQ43_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH2743489.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            1316..1813
                     /locus_tag="KRQ43_003148"
     CDS             1316..1813
                     /locus_tag="KRQ43_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBH2743490.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNAIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVILAGKYAKFVIVGGQKEVGDFWFKFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            2557..2919
                     /locus_tag="KRQ43_003149"
     CDS             2557..2919
                     /locus_tag="KRQ43_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH2743491.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVNNVLK"
     gene            2985..3602
                     /locus_tag="KRQ43_003150"
     CDS             2985..3602
                     /locus_tag="KRQ43_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HBH2743492.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            3599..4084
                     /locus_tag="KRQ43_003151"
     CDS             3599..4084
                     /locus_tag="KRQ43_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HBH2743493.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            4127..4645
                     /locus_tag="KRQ43_003152"
     CDS             4127..4645
                     /locus_tag="KRQ43_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HBH2743494.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            4781..5740
                     /locus_tag="KRQ43_003153"
     CDS             4781..5740
                     /locus_tag="KRQ43_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH2743495.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNTRTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            5766..7469
                     /locus_tag="KRQ43_003154"
     CDS             5766..7469
                     /locus_tag="KRQ43_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HBH2743496.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINRV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            7726..9828
                     /locus_tag="KRQ43_003155"
     CDS             7726..9828
                     /locus_tag="KRQ43_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBH2743497.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESTDEKEAIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKNVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQINEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMHGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            9841..10281
                     /locus_tag="KRQ43_003156"
     CDS             9841..10281
                     /locus_tag="KRQ43_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBH2743498.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            10317..11120
                     /locus_tag="KRQ43_003157"
     CDS             10317..11120
                     /locus_tag="KRQ43_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBH2743499.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKSFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            11160..11756
                     /locus_tag="KRQ43_003158"
     CDS             11160..11756
                     /locus_tag="KRQ43_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HBH2743500.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGLFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            11862..12725
                     /locus_tag="KRQ43_003159"
     CDS             11862..12725
                     /locus_tag="KRQ43_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HBH2743501.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            12792..13781
                     /locus_tag="KRQ43_003160"
     CDS             12792..13781
                     /locus_tag="KRQ43_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBH2743502.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NRESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            13873..14484
                     /locus_tag="KRQ43_003161"
     CDS             13873..14484
                     /locus_tag="KRQ43_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH2743503.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
BASE COUNT         5976 a         1379 c         2703 g         4590 t
ORIGIN      
        1 tatagaaata agtaaattaa gtaagatgat aacaaatgag atgataataa gtaaattgat
       61 atagtaataa ataaattaag atgataatat ccaaagtgag aaagataata gaaagtaaat
      121 aaaatcatgt aagaataatt tagataagat tctaagattt tatttattta aaaattagta
      181 tgattaattt agattaaata aatttaataa ttttagtagg tggtaatgaa tgaaaataaa
      241 tagattaaca gaaataatag taattctatt aaataaaaaa ttagtaacag ctaaagagtt
      301 ggcagatagg tttgaagttt ctacaagaac catatataga gatatagaaa ctctgtctat
      361 gtcgggagta ccagtatata tgacgaaagg caaaggagga gggatatctt taatagaaga
      421 atattctata gacaaggcca tactgtcaaa aaaagataaa gagagtttaa tagttgcact
      481 gaaaacatta caggcgacta agtatccaga aataaattca gtagtaaata aaattggctc
      541 aatatttgga gagcagaatt tttcaaactg gattgaaata gactttactg aatggggaag
      601 taattttaat gaagatgata aatttacaaa aataaaagaa gctattttaa gacgtaatac
      661 tataaatttt aattatgtaa atagtttgtc aagccagaca aacagaactg tcgaaccact
      721 gaagcttatg tataagagta agacttggta cttgtatgga ttttgtaaac taaaagatga
      781 ttttaggata tttagaatta gtaggataag gaatttatct ataaaggatg aagtattttc
      841 aagaaagata atagaagaag tatgtttgaa tgattctaaa gtaattaagg aaaatactat
      901 aacgttgaaa ttgaggttta aagaaaagat gctttttaga gtatttgatg attttaataa
      961 ggatttaata actaaaaatg aagatgatac atatgatgta attacagaat ttcctattgg
     1021 tgaatggatt tatggatata ttttatcgtt tggtgacaat gttgaagtac ttgaacctaa
     1081 agatgttagg gataatgtaa taactagact aagggagttg tctaaaattt attcattata
     1141 atatgatgct agattaaaga ttttattaaa tatataatat cttgcattta gtatataata
     1201 tctcactgag tttaattata ttaaaaatat gacataaagg tgtcgtatat tataaattat
     1261 aattgaatta gttcaaaata aaatatatta ataaaaacaa agtgaggtat aaagtatgaa
     1321 ttatgaaata gtagagataa atgagaaaat agttatagga atatcgaagg agactacaaa
     1381 taaagatgga caagcggtaa atgctatagg tgaattgtgg aaaaaattta tgggcaaagg
     1441 gatatataat gctataaagg gtaaaaagaa tgacaagaca ataggtctat atacagatta
     1501 ccagggtgat tttacaagtc cgtatagctt tgttgcatgt tgtgaagtaa atagtaattc
     1561 tgataaagag aagaatttag aagaattaaa cactaataat actgttggag aaagtattat
     1621 tagtaaagtt atactagcag gtaagtatgc aaagtttgtt atagtaggag gtcaaaaaga
     1681 agtaggagat ttttggttta agttttggca aatggatttt gataggactt atataagtga
     1741 ttttgaagag tatcaatgta atacttttga tacaaagaaa caagaaattc atatttacat
     1801 aggaataaag tagatttgtt attactatat tgaatgaagt attgagtata gtacatttat
     1861 tatagatagt tttactattt ataactataa gcagtaaatc tgtaaaagat ttactgcttt
     1921 tttagtaatt aatagtatca gtatcacttt gaatcttcag acatattcgt catttaatat
     1981 tgtttattga taaatgatac ttgtaaatat aatgatttgt tatttaattt aaaatatgaa
     2041 aaaaagtatt ataaacacat tagaatactt ctggatttat gagtatacaa tttgaaaaat
     2101 ataaaaaata atgtataaag ctaaatctaa tttaatcgat aatacatata gagaaatata
     2161 attaagtaaa taaacaacta tctattagat attgagaaag tcaaatccta tatgaatcta
     2221 cagaaatgat tttaatgaat ctgaaaaaat tttttataca aacataaaaa aggtataaag
     2281 ttgttttatt ataatttgat tacttttgat aactttttat gttttataca attatatttt
     2341 taataactcg tcaaaacgcc aaacatatat tacaatagat atataagttt ttttgttgac
     2401 aaattatgtt aagagaatta agtataatat ggcataaata attactttta tttatcaatg
     2461 aaatgtattt attgtgtagc gaaaaatagt cagatagtat agacaataac tgaagataaa
     2521 agcgtttatt gttgtacata tggaggagtt agttttatgg aaaataaaat tttgatagta
     2581 gatgatgcta tttttatgag aatgataatt aaagaagctc tgagtaaaag tggctataat
     2641 aatttaatag aagcaaatga tggagaagaa gcgtgtaata tatttaaata tgaaaagcct
     2701 gatttgatgt tgcttgatat tacaatgcca aaaaaagatg gtttagaggt gctaagagaa
     2761 ataaaaaagt tggattcaag tgctaaggtt gtaatgtgct ctgcaatagg acaagagaat
     2821 atgattgtag aagccataaa acttggagcg ttagatttta tagtgaagcc cttcaaaaca
     2881 gaaacattag ttaaagttgt aaataatgtt ttaaaataaa agtgtaaata tacactgata
     2941 caatgaaaag caaataaatg caataataaa agggaggggt ttatattata aattatttag
     3001 aacttgatga tgttcatata gatgctctta gagaaattgg taatataggc tctgggaatg
     3061 caattactgc acttgcatcc atgataaata gcaatgtaga agtattaata cctatggtca
     3121 agatacttga atataatgaa gcgacaaatt tgcttggtgg tccagaaaac aaagtagtat
     3181 gtattttact cgatatgaaa ggtgatatca atggaatgtt tatgtttttg ttggatgaat
     3241 caataactca acttatgcta agttctcttt ttaataaaga agaagctttt ttagatgaga
     3301 ttgaggcaat tgaaatttca gcaattaagg aaataggaaa tattatggca agttcatatg
     3361 taaatgctat tgcatctatg ttaaacatga ctataagtgt ttcaattcca gatatatgta
     3421 ttgatatggt tggagctgtt ctaaatgtgc ctatgataag attttcagat gttggtgaca
     3481 aagtcttatt tatagaaaat aaatttaaaa tgagtgataa ttattttact agccacattt
     3541 tgatgattcc agaaatgagc tcacttagag aaatactcgt gaggttggga ttagaagtat
     3601 gaatagagag atagtagtga acattgcaga tatgaagata gcctatagac caaatgtttt
     3661 agttacttat gcacttggct cttgtgtagg agtatgtttg atagataaag tagctggaat
     3721 tggtggaatg ttacacgtta tgttgccata tagtaaagat gctattaaca ttgaaaataa
     3781 gtgtaaattt gctgacacag gaataaatga gctcattaaa tctatggaga atataggtgc
     3841 aaatagaata tatataaaag caaaaattgc tggaggtgct cagatgtttt taggaagcag
     3901 caattcagta attgcaagta taggacatag gaatgttgag gcagtaaaaa aaactctttt
     3961 aggattaaat attccaatat tagctgagga cacaggtatg aattatggta gaacaatacg
     4021 tttttacact gagacgggtg aattacttgt agattcaata aataaaggta agaagaaatt
     4081 ataatatata tttcatagaa agtgtatttt aggagggagg tattaaatga gatttccaga
     4141 tgacccatat ttagattatg gactaattga tgaaggaatt aagtatctaa agtttaaagt
     4201 agatgagcaa gattttgggg ttgaacttga aaaggtaata gaaattactg gaaatcaaga
     4261 aattatattt attccagaac tacctacata ttctaaaggc ataataaatc taagaggaaa
     4321 aatcattcca ataatagata tgcgtttgag acttaaaaaa gatgaattaa tgactacaaa
     4381 ttgcatgtat atagtagtaa ctgaaataaa ggacttggta gttggatttg tggttgatag
     4441 agttgatgat atagtaagct tagaaaaaag taaaatatca cctccaccaa gagttactat
     4501 agaatattcg gattattttg taagtggcgt tggagaatta gaaggtaaaa taattacttt
     4561 actagattta gagaaacttt tgacagataa agatgaagtt ttaatagatg aattaatcaa
     4621 tgggtttgat tgcactatca tgtaacatag ggatgtagtt ggagtgttat tataaaaaga
     4681 ttgtgatgag aacatttaag aatatagtgg tataattatt aagtataaaa attttaaatc
     4741 attaaaattt gaatatatta tgtttaagag aggtttgtat atgaaaaata agcaacaggg
     4801 aacaatttta gtcgttgatg atagtgttct gatgtgtgac ttaatagata aaacacttac
     4861 aaaagataat tttaaggtta aaaaagcatt taatgcaata gaggcaaaag aatttattga
     4921 agaatttata ccagacatta ttttgcttga tataatttta ccagataact ctggttttga
     4981 gttttgtaag gaagtaaaat ctaatactcg tacagcagat atacctataa tttttataac
     5041 ttcaaaaaat acagatacag acatagtaaa aggatttggt gtaggagcaa ttgactatat
     5101 ggtgaaacct tttagtatga cagaattaaa agctcgtgtt atagctcatc ttgaagtaaa
     5161 gaaatctcaa gataaattaa aaaagataaa taatgaactg gaatcttctc ttgaaaaatt
     5221 gaatagactc gttgtaagag attatcttac aggtctttac aataggcgac atataattaa
     5281 tcagcttatg gagcaaagaa gaattaataa atatagtgaa acatcaatat cccttatcct
     5341 tggtgatatt gatgacttta aggttatcaa tgatacttat gggcatgaag caggggattt
     5401 cgtgttaaca gtaatatcaa gtataataaa aaagaattgt agacaaattg atactgtatc
     5461 aagatggggt ggagaagagt ttttgataat gctcacaaat actccaatag aaggtgctaa
     5521 gatactttca gaaagaatcc gtaaagagat aaaggagttt gatttcaact ataaagaaca
     5581 taaaataaag tgcactatta cattaggagt agtagaagta aactcaaata tatcattaga
     5641 agaaaacata tccttagcag ataaagcaat gtatgagggt aaaaacttag gaaaagattg
     5701 tagcgtagtg agtacaatga aaggattaaa aaagatataa acttacttta tgaaggagta
     5761 cagatatgaa aagagaagta aagctttcta aattagcaat tgtattgctg attattatag
     5821 tattggctgt tctagcaggg attttttctt ctatttcatc ttataaagca tttgaaaaag
     5881 tagaaaaaag tattaatgat atgaataatt tgaggactca aagtcagtat ataaaagata
     5941 caactagaga gataagtgat gtattaagaa gatatgtatt tacaggagaa aaaaagaata
     6001 aagatattta tgaaaaagaa ttatacggaa aaacaagaga atcagcttta aacaaattag
     6061 aaaaaattgg tcttacaaag agcgagtcaa ataaaatctt agaagcaaaa gaaatatcag
     6121 attctttagt accaacagaa caaagtgcaa taaaggcagt cgaaagtaat gataagagta
     6181 aagctcaaag tataattttt ggtagtgact atataaactc ccaagagaaa atggattctt
     6241 taataaatga atttcaagag gatatagtta cccgttcaaa ttccaaaatt gtagaagtaa
     6301 aaaaagaatt acaaagtcta atattaagaa caatatttat actttccctt ttaataatat
     6361 tgacaataat agaatataca gtaataaaat taaagatagt gattcctatt aatagagtag
     6421 aaaaacactt ttcaagaatt gcatctgggg acttaagaac aagtatagac gttgaagaaa
     6481 gtaaatctga aataggacta ttagtgagtt ctgtcaaaaa gatgcaaagt atgcttttaa
     6541 attacataga ccttatagac agtacattaa ctagtattgc aaaaggagat ttaagagtag
     6601 agatagacca agaatttata ggtgatttta aatcaattaa aatatcttta gaaagtataa
     6661 taaactcttt taatggtgat ttttctgaaa taaatttatc agcagaacaa gttgcaagtg
     6721 cttcagaaca agttgcagca ggtgcacaag ctctttcaca gggtgctact gaacaagcta
     6781 gttcagtaga agaattagct tccacgatta atgagatatc agatggaatt aagaagtgtg
     6841 cagatagtgc tagtcttgca tgtgaggtat ctgaccaatc tgcatcacaa gttggttttg
     6901 gaagtagatg tatggatgat atgatgacat caatgggtga aataagtgaa aaatcgagtg
     6961 aaatatcaaa aataatcaaa acaatagatg agatagcatt ccaaactaat attctcgcat
     7021 taaatgcagc tgttgaagca gcaagagcag gtcaatatgg tagaggattt gcagttgtag
     7081 cagatgaagt taggtctttg gctggtaaaa gtgcaaaagc agctcaaaat acagctattc
     7141 tcatagaaga agctattaaa acagtagaaa atggtgtcag aattgctaaa gagactgcaa
     7201 atgcattgga cttggtagta aatggtgtag aaaaaactac taattatatt aatggtattt
     7261 cttcggctgt acatagtcaa gaagtagcaa ttacacagat tttatctgga atagagcaaa
     7321 tttccatagt agtccaaatg aactcagcaa cagcagagga aagtgcagca gcctcagaag
     7381 agatgtctgc tcaagctcaa attttaaaag aattagtaga aaaatttcat ctaaaggaaa
     7441 gtgaagtaag agaatcatca tgggtttaaa ttatgaggtg aatattgaag taagagaatt
     7501 atcatgtatt taaattatga ggtgaatatt gaagtaagag aattatcatg tatttaaatt
     7561 atgagatgta tatatattga aataagagaa tgattgtgta tttaaattat gaggtacata
     7621 tagtgagata agagaatcat caaggattta aattatgaga tgcatatata atagaaaatt
     7681 atttgtaggt cgtaggtgat aaatgtgaat tatattgaac cgagtatgag acaaatgtta
     7741 gatatgttta tatttgagac aagtttatta ctcgaacaat tagatgaaat tatgattcaa
     7801 atagaaaaag agaaagtatt tactcataac aacattaatg aaacttttag aataatgcat
     7861 acgataaaag gttcagcatc tatgatgggg ttagacaata tatctgcttt agcacatagt
     7921 gtagaagact tgttttatgc tatacgtgaa ggtaaaatag aagttttaga caatgaccta
     7981 ttatttgatt tagtctttca atcattagat tttataagaa gagatataga tgagctacaa
     8041 tcaagaggtt gtatatcttc tgattactct aattttattg aaggaattga agagtatgtg
     8101 agtactttgg aattatcaag ttctatgaaa tcaaaggata atgcaaattt agaaagtaca
     8161 gacgaaaaag aagcaatcga ttcaaatttt gaatacaaag aagactctga tgtagtaaaa
     8221 ataatctttg aacaaggttg catgatggaa aatgtgagag cgttcatgct tgtatttgaa
     8281 cttagagatt actgtgaatt tatagatttt tatccaaaag atgtagaaac aaatgcagag
     8341 tctacagaat atattaaaag ttatgggttt tatatacaat ttgtagctaa agaggataag
     8401 gcaatagttt ataaaactat agaagataat ctctatgtaa aagaatacat aaatattagt
     8461 aaaaaagaaa tagaaatgaa aaatacatca aataatgatg cagtagaaaa taaattaaaa
     8521 gataataata aagtaagtaa aagttatcaa aataactata cagaagatga gatacaagaa
     8581 gatgttttaa atgaaaaaac tgatatggaa aaagatagtc taagtgaaga aaatgaacat
     8641 ttaccaataa gtaagcagag tattatgagt gtaaatttag aaaaattgga tttacttcaa
     8701 aatatagttg gagaaattgt aattatggaa tcaatggttg taaatagcgt aaattctaca
     8761 ggtgttgata tagataattt caataaggca acaagacaat tacacaagct tacagatgaa
     8821 ttgcaagata tagtaatgtc tatgcgtatg attcaaattg ctggtgtatt tcaaaaaatg
     8881 catagaattg tacgagatat gaataaaaaa ttagataaaa atgtagagtt aataactata
     8941 ggagcagaga cagaggtaga taagaatgta attgataatt tagcagaacc ttttatgcac
     9001 cttataagaa atgctatgga ccatgcaata gagcctattg aggagcgtat agcgaaaggt
     9061 aaagaagaag tgggaaagat agttttatct gctgagaatc taggcggaga agctgtgata
     9121 agtatttcag atgatggtag aggcattatg agagataaga ttttggcaaa agctaaggaa
     9181 caaggtcttc ttaaacatca aattaatgag tatactgatg acgaggtcaa ttctttgatt
     9241 atgactccag gtttttctac aaaagaatct ataactgaat tttctggaag aggagtaggc
     9301 atggacattg ttcgtaaaag tattgaaaaa gttggaggtt caattgaagt aaaaagtaaa
     9361 caggatgaag ggacaacctt tactataaaa ataccattaa ctctttctat agtagagggt
     9421 atgaagttta aagttggaga ttcactattt actttaccaa tatcatccat aagaagaaca
     9481 tttaaactta cagacttaaa tcaaataatt acagaaggaa ataagacaga gttaattaca
     9541 atatatggag catgtattcc cattataagg ttacataaaa tatataatat tcaaacaaaa
     9601 gtaaccaatc tgatgcatgg taatatgata attattgaaa atgagcataa agcagtatgc
     9661 atttttgttg atgaaataat aggtaatcag caagttgttg tgaaaccatt tccagtttat
     9721 ttcaaccgat ttaatataaa aaataagggt ttatcgggat gtacaatact tggggatgga
     9781 agtataagtt taattataga tgcagatagc attatagaaa tatattaggg gatttaaagt
     9841 atggctaaag atgaaattat taaacaagta ttaacatttt atgtaaatga tgttatttat
     9901 ggaatagaat tagaaaatgt gattgaaacc ataagatttc aatcaataac gtatgtacca
     9961 tgtcttccaa catatataag tggagttatt aatttgagag gaagaataat accagttatt
    10021 aatatgcata taaagtacaa tcttcctaaa gctgattata atgagagaac ttgtataata
    10081 attacaaagg ttgatgagta tcaagttgga attattgtag ataaagttgt tgatgttatt
    10141 catatagaaa atctaaattt actagagacg actaattcta acaacactaa tattaataaa
    10201 gatataaaag agattgcgaa agttgaagat aattctatat taattttaga tattcgaaag
    10261 tttttgatta atagcatata gttagttctg ataaattagc aggaggaagt ttttgcatga
    10321 taaaactcac agatgaagaa tttatagttc ttgtaaacca tgtaaaaaaa gaatatggta
    10381 ttgatttaag taaaaaaaga gcgttaattg aaggtcgctt atacaataca atgatagaga
    10441 aaaaacttag ttcttttagt caatatatga atctattatt taaagataag acaggaaatg
    10501 aagctataaa cctaataaat agattgagta ctaaccacac attttttatg agagaacctc
    10561 aacattttga gtttatacag aatagtatac ttcctttttg ggaagaaaat aataaaataa
    10621 gaaacataaa tatatggagt gcaggatgtt ctagtggaga agaagcgtat tcaatagcta
    10681 tgactttgga tgattatttt ggatataata aagagttgtg gaacattaaa atcatagcca
    10741 cagatatttc aactaactca cttgaaaaag ctaaaagagg tatatacata gaatcaaatg
    10801 ttaacaatgt tcctgagtta tggaagaaga agtattttat agacaacaag gatggtacat
    10861 ttaaaatttg tgataagatt agaaaaagtg taatttttaa gtcatttaat ttaatgaatg
    10921 atttctcata tcaacatttt gatttgattt tttgtagaaa tgttatgatt tattttgatt
    10981 taaaaacaag agaagaactt ataaataaat tttataatgc taccaaaaaa gatagttttt
    11041 tgtttgtagg acatgcagaa gtaatcaaca gaagtagtac taaatacaaa tatgtaaaac
    11101 ctgctatata taaacgataa aaaggtattt ttgatatatg attttttgga ggcggtaatg
    11161 tggaacgttt taataatatg gttattgcta taggcgcatc tgtaggtggt acagaagcaa
    11221 tacttgaaat tataaaagac ctaccaaaat caacaccagg gattgttgta gttcaacata
    11281 tgccagctat atttacttat atgtatgcac aacggcttga caagcagtgt attatgaatg
    11341 taagagaagc taagaataat gatagagtcg aacaaggaaa tgtgttaatt gcacctgggg
    11401 gttaccagat gaaattgtgt acggataaac aaggatatta tgtaacttgt gaaaaaggag
    11461 aaagaataag tggtcactgt ccatcagtag acgttttgtt tgattcagta gcagaagtag
    11521 caggtaaaaa ttcaatagga ataatactta caggtatggg ttatgatgga gcaaatggac
    11581 ttttaaaaat gaaagaaaat ggtttattta caattggaca ggatgaaaat tcttgtatag
    11641 tatatggaat gccaatggta gcttttgata gaggttctgt tatgttacaa ttacctcttg
    11701 gtgaaatttc aaactgtttg ataagacata ttaatatttt aaaacaaaaa gattaatttt
    11761 ttataaataa aaattaatct tttattaaat tatatggata aaaaacccta gaaactccaa
    11821 atataataag agagatttat atttaggagg aaaatgataa tatgaaattt tttaaagtcg
    11881 atacaaaagc taaagtttta agatatgtat ttgttttaac attgactata atggctgttt
    11941 tggcaattaa acatgactat aaatataata atttaaggaa agatgcttca attaatttaa
    12001 atagtaataa ggaagcagtg actgttatga gtaaccagtc attaccaaag ggtaatacaa
    12061 atagtaaaca aactttatca gtaagtacaa taggaagtaa aacaatagtg aaaaatgatg
    12121 agtatttaga aagtactata aacatgcctg taataacaaa ttcaaataaa attgttgaaa
    12181 ggtctacaaa tgataagata aaaaatgaca tatttgaatt ttataataaa tcatataaag
    12241 aagcaaagca gtatcttaag gataatcctg acgagaaaaa taagtttgtt gcaaatgtag
    12301 actttgaact taaaaagaat actgattctg ctcttagtat aaaagtgaga tattatactt
    12361 atagtggtgg agcacatgga ttttatcaag atatagcata taatgtggat atgagaactg
    12421 gaaaattttt agaattaatg gacttattta aggataatac taaatataaa gaagttatag
    12481 atgaagaaat taaaagacaa atagctgaac ttgaaaaaaa ggatgaagaa aatatcggaa
    12541 tatataattt taaaggtata aaagagaatc aaaactttta cttgcaagat gagaatctag
    12601 ttgtatattt tgatttatat gatataactc catatgcagc gggaatacca gaattttcaa
    12661 taaataaagc gttgataagt tctatgctaa aaccagagta tgtagattta tttgatttga
    12721 aatagaagat taaattaaat gttatgctat aatatttagc atagaaactt attaaaattg
    12781 ggggtataaa aatgctactt ttaaaaaaag acgacataaa aaaagtattt acaatgagag
    12841 atgcaattga agctgataag gaagctttta gaatttattg tgaaggaaag agtgtaaatc
    12901 ctttgagaac caatatatct gttccaagtc aagatgctag tatgttattt atgccaggat
    12961 acgtagaaga attaggctgt gggggaataa aaattgtatc tgtatttcct aaaaatgctc
    13021 aaaaaggcaa accagtaatt ccagcaacag tactattatt agatggagaa actggagaag
    13081 ttagtgcagt attggatggt acttatgtaa ctcagattcg tactggagca gcctctggag
    13141 cagctataga tgtattggct aaaaaagatt ctaagattgg agctttgata ggtctaggag
    13201 gacaaggtga gccacaactt gaagccatga tagaagctag aaatttggat gaggtaagag
    13261 tttttagtag aaacagggaa agtagagaaa aatttgcaga agaaatgaac ttaaaattaa
    13321 gtaaatataa tactaaaata gttgcagttg aatcatctga tgaagccata gataacgcag
    13381 atgtgatagt tttagctact ccatcaaaac aaccagtact taatggaaac ttagtgaaaa
    13441 aaggagcttt aataagtgca gtaggttcat atatgccaga tatgcaagag ttgtgcccaa
    13501 actgtttaac tagagcgtct aagatatttt ttgaatcaac agatgcagtt ttatctgagt
    13561 caggagatat attaattcca ttaaaagaag gtaagataag taaagatgat tttagtggtg
    13621 atttaggaaa cgttataaat ggaactattc ctggaagaga agatgatgat gagataattg
    13681 tatttaaaac tgttgggata ggtgtacaag atgtcgtaac agcaaaaaga atatacgata
    13741 aagcaaaaga aaacggtatt ggaatagact ggaagtggta aaatattcaa aataattcta
    13801 tagttagaca aatttatgtt ataatgttga taaataaatt ttttattatt ttaattgagg
    13861 gaggatgttt gtatgaaaat ggtaaaaaag ttaatattgt ctacgattat ggctctagtt
    13921 ttagttctaa ctatagggtg ttctaatgca gaagaaaaag taaagtcgaa ttttgaagct
    13981 aatttagctg cattagaaat gtataagtat gatgaaaaag gaatttctga tgcattaaca
    14041 gaagctgaat ataaacagat tcaaacttat aacagcaagg acaaggtttc aatgattgct
    14101 caattgacac ctctttatgg taaagaaaat gctgaaaaga tatacgaaac aattgttaaa
    14161 ttaattcaag gtgttgaaaa gacagtaaca gtggaatctt ctagtaagga taagataact
    14221 ttgaaagttg taagtaaagc tttagatact agtaaagtaa tgagtgaagc gaacacttta
    14281 gtaaaatctt atgtaactga tgaaaagaat tacgataaaa aagaaaaaga agttcaagat
    14341 gatatgacaa aaatgattat agacctttac aataagaaac caactaagga agttacaact
    14401 atgattacat atactaaaaa agatggtaaa tggcaaccac ctagtaatat acaaaagtta
    14461 tgtgaaggaa tatatacaat ttaatttatt ttaaagacac aaaactatct tttaagcata
    14521 taataaaatg tttggaagat agtttatttt attttcaaag tataaattat attttataaa
    14581 tgatttattt tataaataat ttatcttgat aaatagtaaa taatttactt tactaataat
    14641 aaataatt
//
LOCUS       DAEQJM010000082        14600 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.083, whole genome shotgun sequence.
ACCESSION   DAEQJM010000082 DAEQJM010000000
VERSION     DAEQJM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.083"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            319..930
                     /locus_tag="KRQ43_003162"
     CDS             319..930
                     /locus_tag="KRQ43_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743504.1"
                     /translation="MNIKRINLLLSTVMAAVIISLPLAVTANAMEKTESDNNVKIELS
                     DKEVEELHNYWPEDKIFSDEKIDEILIKTGQFTQKELDKINQEVDDSAKKVNQNSRVK
                     YINGYNKYRTFTKNGKNYLYIYVSGKTLKKIKAGTDLASTFGGFLPKIWVELDVVAIG
                     KIITINMDGINTNYGIVLSYIEDKWNFQGATYTYRYDHWFYQT"
     gene            958..1140
                     /locus_tag="KRQ43_003163"
     CDS             958..1140
                     /locus_tag="KRQ43_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743505.1"
                     /translation="MKKRLYKVFLKTIPNLIIVILSLALSFYTNTFDIDLKILLLIPL
                     AYVLLFIYYYIKTKKD"
     gene            1380..1922
                     /locus_tag="KRQ43_003164"
     CDS             1380..1922
                     /locus_tag="KRQ43_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2743506.1"
                     /translation="MLIYLAILELEEDKIKFEKVYEKYRQIMFYVANKILKDDHLSED
                     AVHNAFLRIIKNIDKIDEVDSPRTKAFIVIIVERIAIDFYRKRKREKVSDIEEEYKNR
                     EINFSIEDKVCESNLAIALAKLNESYFQVLSLKFQYGFSNKEIANALNLGEENVYKRI
                     QRARKKLKEILEEMEVGNIE"
     gene            1954..2616
                     /locus_tag="KRQ43_003165"
     CDS             1954..2616
                     /locus_tag="KRQ43_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HBH2743507.1"
                     /translation="MLRESIPIATKIIIDDLLSDDELNHVFSKGFERKMKKLIKQQKR
                     SSLTNKIIFYSKQTAIVFLIVLASLLTITMSSEALRSRFFRLVIRVYEDLTSFVFSTN
                     GEDNLSLKNKEPEYIPKGFKEVDRVDDFVITYRNDENIEIQYVTDKISSNSIILDTEN
                     AKVKDIFVNGHKAKYIVKGTFLQLFWNDNNFIYLLNVDYQNSGESEFYEDILIKIAKS
                     IK"
     gene            2806..3123
                     /locus_tag="KRQ43_003166"
     CDS             2806..3123
                     /locus_tag="KRQ43_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743508.1"
                     /translation="MKSDLYLCKSNKLYRDNEVLEKFMEDLSFLIDDYKFSLETISIL
                     CKINIEKLTNFYAGKGYILYEEMSLIESVLAPFLSAIDIAKHNYDVVIKSRESDKPLI
                     FEN"
     gene            3145..3588
                     /locus_tag="KRQ43_003167"
     CDS             3145..3588
                     /locus_tag="KRQ43_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743509.1"
                     /translation="MKRLFALLLTLSLVILPSTLVFANEKAENDSIYAEAPLVFQSNE
                     KAYTHGSGGTAYIGYMSSKHLNWRITSSKGIVILFSGTVEIRNSKNMLVASYPISGGG
                     SSTISGQIDVKYLKKGDYKAILKGTSTTGGGVLVVKSGLVQMFTI"
     gene            3806..4249
                     /locus_tag="KRQ43_003168"
     CDS             3806..4249
                     /locus_tag="KRQ43_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743510.1"
                     /translation="MNLRKTVISGMCALVCSSAVAIPAFADEYQDKNIEQYSAVNYID
                     DTMVKMSYIKSGTCNLSISGSTAKVTCFVRGASNVTSTSIIARLQKSNDNGKTWSTIQ
                     TWNASGNISCSLSKSKTIGKGYYRVHSTIKANSESKNIISSTKKY"
     gene            complement(4380..4800)
                     /locus_tag="KRQ43_003169"
                     /pseudo
     CDS             complement(4380..4800)
                     /locus_tag="KRQ43_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            complement(4778..6055)
                     /locus_tag="KRQ43_003170"
                     /pseudo
     CDS             complement(4778..6055)
                     /locus_tag="KRQ43_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899679.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            complement(6078..6620)
                     /locus_tag="KRQ43_003171"
     CDS             complement(6078..6620)
                     /locus_tag="KRQ43_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743511.1"
                     /translation="MLLCDPASAGGSKHDYSAFLVGSESENGLLCGRLAELAKINART
                     DFDKYILHMIYLLKVYPDITHVYIEKNTFNGTAANQLELKIKNDDVLYYRDIEIINEH
                     QKKNKDDKISTLIPVLNKGQMIFAEEDKAFIQQILNFTGQKYSLHDDAPDISAEFINR
                     IFNIKVNESITLLDRRNLGL"
     gene            complement(6660..6878)
                     /locus_tag="KRQ43_003172"
     CDS             complement(6660..6878)
                     /locus_tag="KRQ43_003172"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743512.1"
                     /translation="MLFDFKNTNHLEDAKEFYWENEKEIKFPILWPSFWNCLDMALSY
                     YENPTSFKQEVQNDVNSIGEKWFKTIRT"
     gene            complement(7074..7817)
                     /locus_tag="KRQ43_003173"
     CDS             complement(7074..7817)
                     /locus_tag="KRQ43_003173"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743513.1"
                     /translation="MDNLERNIQLIFSYMAKTFIRNGATIREAEKEANEIIKTNSSNL
                     WGVNGLAYQLGKINLEFFCMYFIQDTYLPKEDNVAAPIAKVHHELWEDIQESIIGDGS
                     QQLGRIYPRGTGKSAFGDLATTVWSHCYKHKTYTLICSDIGSTAEKFVKDIKNALLEN
                     EYIKKAFGVLLNDNDRKYICNSTQLELTNKTFIEAISSSSPMRGKKYNNNRPDLIILD
                     DYQSEENVRTEDAREKKFKKFSDDVKYAA"
     gene            complement(8117..8674)
                     /locus_tag="KRQ43_003174"
     CDS             complement(8117..8674)
                     /locus_tag="KRQ43_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH2743514.1"
                     /translation="MVVGYMRVSTAEQNEDRQLVTMKKHNVEKMYQEKISAKDTKRSK
                     LNAMLDFVREGDTIIVHDFSRLARSTKDLLEIVELLEKKHVKLISDKENLDTSTPTGK
                     LMLTMLGAIYEFERTNMLERQREGISIAKEQGKYKGRKEVKIDNFGSYYDRYKTRELN
                     KTQLAKELGVSRPTLDRLIKSHESN"
     gene            complement(8869..9057)
                     /locus_tag="KRQ43_003175"
     CDS             complement(8869..9057)
                     /locus_tag="KRQ43_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743515.1"
                     /translation="MNNKKKSFLISGTINVILLIIVFALFSYNIIENSTRNMIITVIL
                     IFIFEIIKIKILEKYYNL"
     gene            complement(9068..9643)
                     /locus_tag="KRQ43_003176"
     CDS             complement(9068..9643)
                     /locus_tag="KRQ43_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743516.1"
                     /translation="MLKKKIISFLMAGIFVLSSGYNLVYASTFEENEYKQELVNENEF
                     TIINSNENEMIVDKKGNNTYVSTKVTPGSWKNVKYLGQKSRKLSSPYTRERIIQTIQW
                     GLGYLSGGSSFLLGLAESIYREKVYDITKYGGVYTKTYYRRQITDIRNSHANVPVPYR
                     YEYVTYFYSSSNFKKVVYTERVGDGIKLANN"
     gene            complement(9976..11115)
                     /locus_tag="KRQ43_003177"
     CDS             complement(9976..11115)
                     /locus_tag="KRQ43_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH2743517.1"
                     /translation="MVIKLTIEEYKNKYSTGDKIILSLKSFDNKELYYHETDNILNSK
                     DEIDRLTSSKIFKIIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYNLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLDPLKIYNFMDELIIFMENSKVNDLVKSTIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLINKGYDTFKEFSISYIISKNRTKYYKAILDVENKGYNLTVFIEFMLKSIIQSINEM
                     RDMHDRKSLESILKEELFENDITLSATEEHILKYICSKDNYSMTLENYIKKNKGRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSREKDVYKVNEKYLNMLEIS"
     gene            11452..12705
                     /locus_tag="KRQ43_003178"
     CDS             11452..12705
                     /locus_tag="KRQ43_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBH2743518.1"
                     /translation="MLNKKNISSIIMTMILSLSTTVFVFADENTNVKGQDVTKYNEEM
                     VSKNLEDLSIEQLIDIRDKAIDKNLEGLRKFGEDSVKERKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVEYENSINDIMDPSGDFFKVTNQSYQINEFVLKNGKNYKEWSY
                     EYVEFLIEHLEDLCNFVDFDAKYVIEMVDPSIKPDLSDNQKKSLNNELIKMYSSNTLS
                     TNIKDEIENWENNLNINEKNSNEPLPRVSPSSYRQQALAYAKKHGYTNGYYGSTNRKN
                     NAPSPYYNFQKDGYGDCANFVSQCLHEAGVTFWTNNNPWYYYSTSNRSPSWAGAREFK
                     IHWMNRIAYQTLTVSNSLSFLRPATPVSILNSSGVATHTLISTDKHSNGYNFSYAAHS
                     DEGARTNLLKKLEGKKISYYKVYWE"
     gene            13039..13770
                     /locus_tag="KRQ43_003179"
     CDS             13039..13770
                     /locus_tag="KRQ43_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743519.1"
                     /translation="MLNKKNVSLIVLVIVLSLFTAIFVFNNRNTNDKSKEIAKNNEEI
                     VPKNLEALSIEQLTKIRDKAIDKNLEGLREFGEDSVKQRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQSYEINEFMLKNKKNYKEWSY
                     EYIEFLIDHLDELCKFVDFDIKDVIDIIDPTIKTDLSEEQKKSLNDKLKKVSSSDTLS
                     EDIKKEIKNWENNLNSLNMNKNNSN"
     gene            14012..>14600
                     /locus_tag="KRQ43_003180"
     CDS             14012..>14600
                     /locus_tag="KRQ43_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBH2743520.1"
                     /translation="MFNKNEILKKLIEEYDVKTTTDIQDMLKDLFASTIHQMLEAELD
                     DHLGYDRYGNKNKNTKNSRNGYRNKNVKSDFGEITLNIPRDRNGDFEPKVISNYKNDI
                     SGIENQVIGMYSKGMSTRDISSHLKSIYGIDISHSLVAKITDRVLPLAHEWQNRPLDM
                     VYPIVFMDAIHYKVRSEGRIINKAAYIAIGVNLEGI"
BASE COUNT         5394 a         1853 c         1861 g         5492 t
ORIGIN      
        1 tacacataaa tatttccaga ctcacttatt gtataagtta tattctattt tgtatgaagt
       61 caattaaaaa ctgaactata ttaaaattaa ttttataaat aacaaatata aataattaca
      121 aaaccttaac tgcgttaagt ttgaaatata ataatattaa aaacacttct ctcaaatcaa
      181 gtatcttttg ttatattttc ataagtttta aaaatataaa ttttttaaaa cttgtgtcca
      241 aaaaacaaaa ttaaatatgt tatatatgta aagggttaat tttaaaacct taaatttatt
      301 atagttaggg ggatttaaat gaatatcaaa agaattaatc tccttttatc aacagtgatg
      361 gcagctgtga taatatcttt accacttgct gttacagcaa atgcaatgga aaaaacagaa
      421 tcagataata atgtgaaaat agagttgtct gacaaagaag tagaggaatt acataattac
      481 tggcctgagg ataaaatttt ttcagatgaa aagattgatg agatcttaat taaaacaggt
      541 caatttactc aaaaggaatt ggataaaatc aatcaagaag tggacgattc tgctaagaaa
      601 gtaaatcaaa attctcgtgt gaaatatata aatgggtata acaaatacag aacttttact
      661 aaaaatggta aaaactattt atatatttat gtaagtggaa agacattaaa gaaaataaaa
      721 gctggaacag atcttgcatc tacttttgga ggttttttac caaaaatttg ggtagagctt
      781 gatgtagtgg caattggaaa gataataaca attaacatgg atggtataaa tactaattat
      841 gggattgttt tatcatatat agaggataag tggaattttc agggtgcaac atatacttat
      901 agatatgatc attggttcta tcaaacttaa aagacatgct tttttaggag gaataatatg
      961 aaaaaaaggc tttataaggt ttttttaaaa acaattccaa acctgataat tgtgatatta
     1021 tcacttgcat tatcatttta tactaataca tttgatattg atttaaaaat attgctttta
     1081 atacctttag catatgtact tttgtttata tactattaca tcaaaacaaa aaaagattaa
     1141 tttttatgga attagatata tacgaaaata attaatttaa aaatttaact ttgagaatca
     1201 tttgtagagt taaggccctt ataatcccga aaatggattt gaagggcctt tttactagat
     1261 atctttaaaa agcttgttaa gcatagttat attctattta agtagagtta attatatatt
     1321 tatgttataa ttgaacttta aaatattaat tcagaatttt tatattggag gaattctaaa
     1381 tgttaattta tctagctata cttgaactcg aagaagataa aataaagttt gaaaaggtat
     1441 atgaaaagta tagacaaata atgttttatg tagccaataa aatattaaag gatgatcatt
     1501 tatcagaaga tgcagtacat aatgcttttt taagaataat taaaaatata gataaaattg
     1561 atgaggtaga cagtccaaga acgaaggctt ttatcgttat aatagtagaa aggattgcta
     1621 tagactttta cagaaagaga aaaagagaaa aggtatctga tattgaagaa gagtataaaa
     1681 acagggagat aaatttttct atagaagata aagtatgtga aagtaattta gctatagcac
     1741 ttgcaaaact taatgaaagt tactttcaag tgctttcctt aaagttccag tatggttttt
     1801 caaataaaga aatagcaaat gcattaaatt taggggagga aaatgtatat aagagaattc
     1861 agcgtgctag aaaaaaatta aaagaaatat tagaagaaat ggaggttgga aatattgagt
     1921 aataaaaaag atgattttga tattacggat gatatgctta gagaaagtat cccaatagcg
     1981 acaaaaatta ttattgatga ccttctttca gatgatgaat taaatcatgt tttttcaaaa
     2041 ggttttgagc gaaaaatgaa aaaactcatt aagcaacaaa aaagaagtag tcttacaaat
     2101 aaaatcattt tttattcaaa acaaacagct attgtatttt taatagtttt agctagttta
     2161 cttactatta ctatgagtag tgaggcattg cgttcacgtt tctttagatt agtaataaga
     2221 gtatatgaag acttaacttc atttgttttt tcaactaatg gagaagataa tcttagttta
     2281 aaaaataaag aacctgagta tataccaaaa ggatttaaag aagttgatag agttgatgat
     2341 tttgttatta catatagaaa tgatgaaaat attgagatac aatatgtaac agataaaatt
     2401 agttcaaatt ctattatatt agatacagaa aatgcaaaag ttaaagatat atttgtaaat
     2461 gggcataaag caaaatatat agtaaaagga actttcttac agttattttg gaatgacaac
     2521 aactttatat atttattaaa tgtagattat caaaatagtg gagaatctga attttatgaa
     2581 gatattttga taaaaatagc gaaaagtata aaataatttt tttaagtgtc caagggtagc
     2641 ctcttcattc gttatacaag tatatatgaa aatgtgaggt gatttttatg gttttaaaat
     2701 ctacatttac ctgagcgtta aaaatattgt tataggaaaa attaatacat tatagttata
     2761 acatgcttgc aataggaata aaactttaaa attgaggtgt aaaaaatgaa atcagattta
     2821 tatttatgta aaagtaataa attgtataga gacaacgaag ttctagaaaa atttatggaa
     2881 gatttaagtt ttcttataga cgattataaa ttctcgttag aaacaatatc tattctatgc
     2941 aaaataaata ttgagaaatt aactaatttc tatgcaggaa aaggatatat actgtatgaa
     3001 gaaatgtctc ttattgaaag tgtacttgca ccttttttaa gtgcaattga tattgctaaa
     3061 cataattatg atgttgtcat taaatcgagg gaaagcgata aacctttgat attcgaaaat
     3121 taatttaaaa ctgggggaat acacatgaaa agattatttg cgttattact tactttaagt
     3181 ttagttatat taccatcaac tttagtattt gctaatgaaa aagctgaaaa tgattcaatt
     3241 tatgctgagg cgccattagt gtttcaaagt aatgaaaaag catatacaca tggtagtgga
     3301 ggaactgcat atataggtta tatgtcaagt aaacatctta attggaggat aacatcttca
     3361 aaaggaatag ttatactatt ttcaggaact gttgagatta gaaattcaaa aaatatgctt
     3421 gtagcatcat atccaataag tggtggagga tcttcaacta tatctggaca aatagatgtt
     3481 aaatatctta aaaaagggga ttataaagct atattgaaag gtacaagtac aacaggaggc
     3541 ggagtcttag tagtaaaatc tggtctagtt cagatgttta caatttaata ttataagtaa
     3601 aataaaaatc atgaatttat tgggggatag tcacaataca tattatttac agatattcat
     3661 aactattata gttaaagaca ttctattata aagaaaatgt ataatttaaa attataataa
     3721 aaaaaattat cattagtgtc caaaaatcac ttcttcattc gttatataag ttatataaat
     3781 agaaaacaaa tgaagaggtg attttatgaa tcttagaaaa acagttataa gtggtatgtg
     3841 tgctttagta tgttcatcag cagttgcaat acctgcattt gctgatgaat atcaagataa
     3901 gaatattgaa caatattcag cagtaaacta tatagatgat actatggtga aaatgtctta
     3961 tattaagtct ggtacttgca atttaagtat ttcaggaagt acagctaaag taacatgctt
     4021 tgttagagga gcatcaaatg ttacaagcac atcaattatt gctagattac agaaaagcaa
     4081 tgataatggg aaaacatggt caacaatcca aacatggaat gcttcaggaa atatttcatg
     4141 ttctctttct aagtcaaaaa ctataggaaa aggatattac agagttcatt ccacaataaa
     4201 agctaactct gaaagtaaaa atataataag tagtacaaag aaatattaaa aatagatatt
     4261 gtatttatga gttgtagtaa acaagaataa tagtttttta aaagcaaata taattaattt
     4321 taaatagagt gccaatataa aataggtgta taatatttat acttttttat attggcactc
     4381 tattttataa aataagttat tatagaaaat gaaacataat ttatatataa attttctgtt
     4441 tgacctggta tataatcttt tatatcacat atcagtattt tcccatcatt ataaccccaa
     4501 ccaatcacag ttgcaggtat catatcagct tctccatcat aaatgattgt atgtttatac
     4561 atgatttttc cctcgctatt atctatagtt ttattcaaaa taccttctgc tattaattta
     4621 gcaactatgt ctttaatagt ctgtatctgc tttactgtct acaaaacata cttcaattaa
     4681 tatcgctgga gcttttgtat gactaagcca atacaattcc cttacgtccg attttgcacc
     4741 tctattttca gcagatttat atatatcttc agtcaattta gttataatct tttgattcat
     4801 ctaataaaat ctctccctct gaaactattt cctgttcttt tttagccttt tccatttctg
     4861 catgaggatt atcaataaaa cttggttgag ataatccggt ttcagtagat aatttatctc
     4921 caagttgact taatatattt gctacaacta aatcattatg tggtatctta ggggtaaatt
     4981 tagccttaat atctttataa tcatagtcaa aaccatattt tttattaagc caaatgcaca
     5041 ataatttgta cctattaaat aaagtatctg caatactatc attattctgg ctacaaatcc
     5101 attctgtact gattaatctt gctacaactg ctaaacttga tgtattactt tgcatttttt
     5161 cattgtgatt tatatgagat gtaattttat atatgttttc ttttattgaa gatagtgtat
     5221 tttgaacaaa tgtatcattc atgtctttaa taagccattc tatttttcca tctccattaa
     5281 cttgaagtat tccaagttct ttcatccttg gcaaatcatc ttctttaata ttacattcag
     5341 agaaggttaa ataagcattt ctaaaatcac taatttcatt acttatatca cttaaattag
     5401 tttcataagc atcttgtaat ccttttatat cattgaatat tgtatttttt cctagttctt
     5461 cacttctttt acaaattgat attggaacat taccattaaa tatattattt actgtaggtt
     5521 tttctatctc tttaaaattt gaatcaaaat gatatatgta ttctttatca tatacatcta
     5581 tataaatatc atctttaaaa tcttttttaa attctctaaa aaaatagatg gtctctccat
     5641 cttcattttc ataatggcag ccatctgttg gttttattat tcttactttc atttcattgt
     5701 tttttacata gtaaagttca tagcaaaatc caaataatag tgtatatctc aataaatctg
     5761 aatcgtgctt tttactccaa tggcaagtat agtattctaa atcatttata atcttctcat
     5821 cacctaatct acttgtatag gtgattttat ttgcaagaga ataagcgacc tcttcattaa
     5881 taaacttttt taagaaatta gtgtttatct tattattaga cctcttggta accattttat
     5941 agttactaat agcatctgtt tcacctttat aatacttata catagtgttg tattcttgct
     6001 tttttaaact ctagtcttca tatatttctc ttaataaact taaatctatt tccatttaat
     6061 gcatcacctc catacaatca aagacctaaa tttcttctat ctaatagtgt aatactttca
     6121 tttactttaa tattaaaaat cctatttata aattctgctg atatatctgg tgcatcatca
     6181 tgtagagagt acttttgtcc tgtaaaatta aggatttgct gtataaatgc cttatcctct
     6241 tctgcaaaaa tcatttgacc tttatttaaa acaggtatta aagtagagat tttatcatct
     6301 ttatttttct tttggtgctc attaatgatt tctatatctc tgtagtaaag aacatcatca
     6361 ttttttattt taagttctaa ttgattagca gctgtaccat taaatgtatt tttttctata
     6421 taaacatgtg ttatatctgg atacactttt aataaataaa tcatatgcaa tatatattta
     6481 tcaaaatcag ttctagcatt tattttggct agttctgcca atctgccaca tagtaaacca
     6541 ttttctgatt cacttccaac aagaaaagca ctatagtcat gtttagaacc acctgcagat
     6601 gctgggtcac ataataacat tgtctttttg aatgtatgag tttctataca ttctctagat
     6661 taagttctga ttgttttaaa ccatttctca cctattgaat ttacatcatt ttgtacctct
     6721 tgtttaaaag atgttgggtt ttcgtaataa cttaaagcca tgtctaaaca attccaaaaa
     6781 cttggccata atataggaaa tttaatttct ttttcatttt cccagtaaaa ttctttagca
     6841 tcttcaagat gatttgtgtt tttgaaatca aataacaact ctttgaaatt aagccataaa
     6901 ccagaattaa ataattcatc tacattatca actaaaactc ctttttcaca tttaaatttc
     6961 caagttggta aattctttag cctactatag aaacattctt tatgttgtaa ggttcctaat
     7021 gctataaaag ttgttcctct ttttataatc ttaccatttc ttattactgg tttttaagca
     7081 gcatatttta catcatcaga aaatttttta aattttttct ctctagcatc ttctgttcta
     7141 acattttctt ctgactgata atcatcaagt atgataagat ctggacgatt attattgtat
     7201 ttttttcctc tcattggtga tgaagatgat attgcttcaa taaaggtttt attagttaat
     7261 tctaattgag tactattgca aatatatttt ctatcattat catttaagag aactccaaat
     7321 gcttttttaa tatactcatt ttcaagtaat gcatttttta tatcttttac gaatttttct
     7381 gctgtagagc ctatatcaga gcaaattaaa gtatatgtct tatgtttata acaatgtgac
     7441 catacagttg ttgctaaatc tccaaatgca cttttacctg ttcctcttgg ataaattctt
     7501 cctaattgct gtgaaccatc tccaattata gactcttgta tatcttccca taactcatga
     7561 tgaactttag ctataggagc agcaacatta tcttcttttg gtaaatatgt gtcttgtata
     7621 aaatacatac agaaaaattc taaatttatt tttccaagct gataagctag gccattaact
     7681 ccccaaagat tgcttgaatt agtttttata atctcatttg cttctttttc agcttctctt
     7741 atagttgctc catttcttat aaaggtcttt gccatataac taaatattaa ttgtatattt
     7801 ctttctaaat tatccactcg tatttacttc ctcttaattc ttctattttt ttaggttcag
     7861 tgagtaatac aattaataaa ataaacaatg caaatttttt tctaataaaa tcaccctctt
     7921 tgaaatatgt ctctggtttt taatttttgc tagaaaattt ctagaactca ttttctataa
     7981 ataatacttt tttgaaatag aaggataccc cctatactga aaaacagtta tttataatta
     8041 ttttaaacat aattaaaggg cataattcta tgaatttgcc ccactaaaat taacttaagc
     8101 atatatattg ctcttcttag ttactctcat ggctctttat taatctatct aatgttggtc
     8161 tacttactcc caattcttta gccaattgag tcttattaag ttctctagtt ttatatctat
     8221 cataataact accaaagttg tctatcttaa cttctttacg tcctttatat ttaccctgtt
     8281 ctttagctat agagatacct tctcgttgtc tttctaacat gtttgttctc tcaaattcat
     8341 atattgcgcc aagcattgta agcataagtt ttcctgtagg tgtacttgta tctaaatttt
     8401 ctttatcact aattaacttt acatgtttct tttctaagag ctcaactatt tctaataagt
     8461 ctttagtact tctagcaagt ctactaaagt catgtacaat tattgtatct ccttctctta
     8521 caaaatctaa cattgcgttt agttttgatc ttttagtatc tttggcactt attttctcct
     8581 gatacatttt ttctacatta tgctttttca ttgtaactaa ttgtctatct tcattttgtt
     8641 ctgctgttga aactctcata taacctacta ccatctttga tacctccacc tatgtttact
     8701 ctataaataa tattatagca taaatgtaaa actagagtta aagatttgcc atgctttttg
     8761 taaattaatt ggagttttga ttttattttt acatcagaat agatagtttg taatgtaaat
     8821 ttgtaccagc atactttaca atatgctctt aggaaagata tttcttgttt atagattata
     8881 atatttctct agtatcttta tttttataat ttcaaaaata aaaattaaaa ttacagttat
     8941 tatcatattt cgtgtactat tttctataat attataacta aacaatgcaa aaacaatgat
     9001 taataaaatt acgtttatag tgccagaaat caagaatgat tttttcttat tattcatata
     9061 tttcctccta gttatttgct agttttatac catctcctac tctttcagta tatacaactt
     9121 ttttaaagtt agatgagcta taaaaatatg taacatattc atatctgtat ggaacaggaa
     9181 cattagcatg actgtttcta atatcagtta tttgtctcct atagtatgtt tttgtatata
     9241 cgcctccata tttagtaatg tcatatactt tttctctata aatactctca gctaaaccta
     9301 ataaaaaaga tgaccctcca gaaagataac ctaatcccca ttgaatagtt tgtataattc
     9361 tttctcttgt ataaggagaa cttaatttgc gtgatttttg acctagatat ttaacatttt
     9421 tccaactacc aggtgtaact tttgttgaaa cataagtgtt attgcctttt ttatccacaa
     9481 tcatttcatt ttcattgcta ttaataatag taaattcgtt ttcattaaca agttcttgtt
     9541 tatattcatt ttcttcaaaa gtagatgcat aaaccaaatt atatccacta gataaaacaa
     9601 atattcctgc cattaaaaaa cttattattt ttttctttaa cataatattt tactaccttt
     9661 acttaaatat ttattctata aacactgtca tataacctgt tagttatatt aaaaataatc
     9721 tttttatata acttcacaat caaaccttgt cttatttcat aatagtttta tttaatatca
     9781 tataatttag acctccttat aagattattt atatatataa cgaataataa aagtaatttt
     9841 ggacaaaata aaaatctttt tattttaaga atgaaaaatt taaccctcta agaaaactca
     9901 attaagagcg attcatagag ggcttattat tatattatat aactttatat actttttatt
     9961 tttatatgct tcaatttaac ttatttcaag catattcaag tacttctcat taactttata
    10021 tacatccttt tctctagata aaatctctat ttcttcaaga ttattaaaca cttccatcaa
    10081 ctggtcaact aattcgattt cttttattcc agcctttaag tatctacctt tattcttttt
    10141 gatatagttc tctaatgtca tagaataatt atctttacta cagatatatt ttaatatatg
    10201 ttcttctgtt gctgatagag ttatatcatt ttcaaataat tcctctttta atatactctc
    10261 taaagacttc ctatcatgca tatcacgcat ttcattgata gattgtatta tagactttag
    10321 catgaactct ataaatacag ttaaattata tcctttattc tctacatcta gtatagcctt
    10381 ataatactta gttctgtttt tagatattat atatgatatt gaaaactctt taaaagtatc
    10441 atatccttta ttaattaaat atagatatga taaggctctt gatgttcttc cattaccatc
    10501 actaaaagga tgaacatata caaagtagaa atgaattatt gtactcttta ctaaatcatt
    10561 tactttacta ttttccataa aaattattaa ttcatccata aaattatata ttttcaaagg
    10621 atcaagtcct gtatgtataa tctcaccttt tgaatcacat acatatactt tttcagttct
    10681 atattcatat tcttctgaat ctaaacagtt ttcacccaat atatgatgta aattatatat
    10741 aaatttgtga ctatataatt tatctaaatt atctaatcca tattctaagg ctctatgatt
    10801 attgtaaatc atatactcac ttttattact tggtttcatc tttcctctaa ttatagattt
    10861 tgcaatcttt ctagttgaaa aggcaccttc tattacacta gaataataag actctaaggc
    10921 taaatcattt ttatcttcta ttattttaaa tatcttgctt gatgttaatc tatctatttc
    10981 atcttttgaa tttaatatgt tatcagtttc atgatagtat agttctttat tatcaaaact
    11041 ctttaaggaa agtataattt tatctccagt agagtattta tttttgtatt cttctattgt
    11101 cagtttaatc accaccttag tttatcttta tctattaata ttaacaaaaa gtattagttt
    11161 ttacactatt tttgattgtt tattttatat attatgattc tactcttgat aattaaatct
    11221 tacttaaaaa ttaattcttg ataattaata aaaaaattta tatataagtg tctaaaaaac
    11281 gattctttat tcgttatata tataaataat actagaaagg gaggattata ttatgatatt
    11341 tagtaaacgc tcttttagaa aaaaacggtg ataaacttgt tttaaatttt agtagaatat
    11401 gatttttgtt ttggcaagta ttaatacata tattaaagag ggaggtttaa tatgttaaat
    11461 aaaaaaaata taagttcaat tattatgaca atgattttaa gcttatcaac tactgtattt
    11521 gttttcgctg atgaaaatac taatgtgaaa ggacaagatg taaccaaata taatgaagaa
    11581 atggtctcta aaaacttaga agatttaagt atagaacaat taatagatat tagagataaa
    11641 gctattgata aaaatttaga aggtcttaga aaatttggag aagattcagt gaaagaacgt
    11701 aaagattcaa ttttaaactt tgaatttgga ttagtagctt ttgttaacaa aaattatagt
    11761 aacttaacag aaaaagagaa attaataaga caaatcaata ttgttgagta tgaaaattct
    11821 ataaatgata taatggatcc ttcaggcgat tttttcaaag taacaaacca aagttatcag
    11881 attaatgaat ttgtattaaa aaatggaaaa aactataaag agtggtcgta tgaatatgta
    11941 gagtttttga ttgagcattt agaggattta tgtaattttg tagattttga tgcaaaatat
    12001 gtaatagaaa tggttgatcc ttcaataaaa ccagatcttt cagataatca aaagaaatct
    12061 ctaaataatg aattaataaa aatgtattca agtaatactc taagtacaaa tataaaagat
    12121 gaaatagaaa actgggaaaa taatttaaat attaatgaga aaaattcaaa tgaaccttta
    12181 ccaagagtaa gcccttctag ttatagacaa caagcattag cttatgctaa aaaacatggc
    12241 tatactaatg gttattatgg tagtacaaat agaaaaaata atgcaccttc tccatattat
    12301 aattttcaaa aagatggata tggagattgt gctaactttg tttcacaatg cttacatgaa
    12361 gctggagtaa cattctggac gaataataat ccatggtatt attattctac tagtaataga
    12421 tcaccttctt gggctggagc aagagaattt aaaatacatt ggatgaatcg aattgcatat
    12481 caaacactta ctgtatcaaa ctctttaagt tttttaagac cagcaacacc tgtaagtata
    12541 ttaaatagta gtggagtagc aactcataca ctaatatcta cagataagca ttcaaatgga
    12601 tataattttt catatgctgc acattcagat gaaggtgcaa gaacaaattt gttaaaaaaa
    12661 cttgaaggaa agaaaatttc ttattacaaa gtttattggg aataaataaa aatttatact
    12721 tttaattaaa tgaaaattga aaagaataaa tatctatttc aagatccaat aagtatttag
    12781 ttgaagcagc tattaaattt tattacataa tcataaaaaa gagactagtg gaatttagtc
    12841 tcttttttat gatttaaaaa tttaataaaa gaattatata aatttgtcta aaaattagtt
    12901 tatcattcgt tataattata taaactatat caaaaaagtg ttctattgta ttctttagaa
    12961 taatcagtaa taaaggttat tctaataaac tgagttattt tttcacaaat aaaatactta
    13021 ttaaaaagga gatttgatat gttaaacaaa aaaaatgtaa gtttaattgt tttagtaata
    13081 gttttaagtt tattcactgc tatatttgtt ttcaataata gaaatacaaa tgataaatca
    13141 aaagaaattg ctaaaaataa tgaagaaata gtgcctaaaa acttagaagc tttaagtata
    13201 gaacaattaa caaaaattag agataaggct attgataaaa atttagaagg tcttagagaa
    13261 tttggagaag attcagtaaa acagcgtaaa gattcaattt taaattttga atttggatta
    13321 gttgcttttg ttaacaaaaa ttatagtaac ttaacagaaa aagagaaatt aataagacaa
    13381 attaatattg ttaactatga aaactctata aatgacataa tggatccttc aggttcattc
    13441 tttgaattag caaatcaaag ttatgaaatt aatgagttca tgttaaaaaa caaaaaaaat
    13501 tataaagaat ggtcatatga atatatagaa ttcttaattg atcatttaga tgaattatgc
    13561 aaatttgttg attttgatat aaaagatgta atagatatta ttgatcctac aataaaaaca
    13621 gatctttcag aagaacaaaa gaaatctttg aatgataaat taaagaaagt gtcttcaagt
    13681 gatactttaa gtgaagacat taagaaggag ataaaaaatt gggaaaacaa tttgaatagt
    13741 ttaaatatga ataaaaataa ttctaattaa ctgatagtgt aaaatgtaca taattataaa
    13801 taaaataggg atgtcttaaa attgattatt ttctaatcta aatattttag gcctatctaa
    13861 aaacataaga ttatggtcta aaatttgaaa ttttagacca tgctttatct ttacaataaa
    13921 tgggtcttta aaataaagtg tgtattcttc taaaaagtgg tgataattaa aatattaaat
    13981 atcactatat aaaggaaggt gcacactttt tatgtttaac aaaaacgaaa tattaaaaaa
    14041 acttattgaa gaatatgatg ttaaaacaac tacagatatt caagatatgc taaaagattt
    14101 atttgcgagt acaattcatc aaatgttaga agcggagctt gacgaccatt taggttatga
    14161 tagatatggc aataagaata aaaatactaa aaactctaga aatggatata gaaataaaaa
    14221 tgttaaatca gattttggag aaataacttt aaatattcca agagaccgaa atggagattt
    14281 tgaaccaaag gtaattagta attataaaaa tgatatatca ggaatagaga accaagtgat
    14341 tggaatgtac tcaaaaggca tgtctactcg agatatatca agccacctta agagtattta
    14401 cggaattgat atatctcatt ctctagtagc taaaattact gatagagttc tacctttagc
    14461 tcatgaatgg caaaacagac ctcttgatat ggtttatcca attgtattta tggatgctat
    14521 acattataaa gttagaagtg aaggtagaat aataaacaaa gctgcatata tagccatagg
    14581 tgttaactta gaaggtataa
//
LOCUS       DAEQJM010000083        14437 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.084, whole genome shotgun sequence.
ACCESSION   DAEQJM010000083 DAEQJM010000000
VERSION     DAEQJM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14437
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.084"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..1022)
                     /locus_tag="KRQ43_003181"
     CDS             complement(<1..1022)
                     /locus_tag="KRQ43_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH2743521.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDINKKMDTIDKLKDI
                     EEGYFYLLEDVYLDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVN"
     gene            complement(1070..1930)
                     /locus_tag="KRQ43_003182"
     CDS             complement(1070..1930)
                     /locus_tag="KRQ43_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBH2743522.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKSI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2209..2418
                     /locus_tag="KRQ43_003183"
     CDS             2209..2418
                     /locus_tag="KRQ43_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH2743523.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2418..2684
                     /locus_tag="KRQ43_003184"
     CDS             2418..2684
                     /locus_tag="KRQ43_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH2743524.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2713..3285
                     /locus_tag="KRQ43_003185"
     CDS             2713..3285
                     /locus_tag="KRQ43_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH2743525.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3519..4709)
                     /locus_tag="KRQ43_003186"
     CDS             complement(3519..4709)
                     /locus_tag="KRQ43_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH2743526.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENVENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSAGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(4969..5400)
                     /gene="dut"
                     /locus_tag="KRQ43_003187"
     CDS             complement(4969..5400)
                     /gene="dut"
                     /locus_tag="KRQ43_003187"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBH2743527.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5513..7741
                     /locus_tag="KRQ43_003188"
     CDS             5513..7741
                     /locus_tag="KRQ43_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBH2743528.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEYEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7852..8337)
                     /locus_tag="KRQ43_003189"
     CDS             complement(7852..8337)
                     /locus_tag="KRQ43_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2743529.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8589..9812
                     /locus_tag="KRQ43_003190"
     CDS             8589..9812
                     /locus_tag="KRQ43_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH2743530.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTKESEPEKPIAVSVQKAVGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNANNKFKAGMSAQVNLSIEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9816..12950
                     /locus_tag="KRQ43_003191"
     CDS             9816..12950
                     /locus_tag="KRQ43_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HBH2743531.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            12984..14282
                     /locus_tag="KRQ43_003192"
     CDS             12984..14282
                     /locus_tag="KRQ43_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBH2743532.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINNVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYKRYEKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNQDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
BASE COUNT         5331 a         2105 c         2118 g         4883 t
ORIGIN      
        1 ttgttaacaa catttaagtt attacattta tttatatata ttttttcatt atctaagtct
       61 tcatcaaaca tttttattat attttttatc tcatacttgt actcatcttc attcattcta
      121 taaagcatta aatcttctaa tacatctttc atgtcgaggt acacatcttc taataaataa
      181 aaatagcctt cctctatatc tttcaattta tctatagtat ccattttttt atttatatct
      241 ttcataattt ctaaattttg tatatttaca tctatgattg ttaataagta cattctcaca
      301 gtttttatta tttcaacaga aaaatctaca atattataat ttccttcttt tttatataat
      361 gactccttaa atttgttaaa acaattatct aaattagaat ttatatcgtt aaatggtggt
      421 cttattatgt cacgtattat taaaagattt tgtatatcta cattatttgt gattgcctca
      481 tccaaaataa ataaattata tgcatcattt aatgggtcat gggcatctcc actaaactct
      541 aagttaacaa attcaagtaa atttttcaat gatatatagt tcatacatct cataccacaa
      601 tttatatatt tttcttttat atctacaaat aaatctctaa tattatttac aaaccttgga
      661 tggttatttt ttttagcact tctcatatct gtgttattga aacatgtcaa atccaaatta
      721 ccaaaagtat atattccttt aatatcagaa aatatgccaa gccatttttt aaattttctc
      781 atgacctctt cataacttgg tgcactcttc aattcttcag aagatatatg tgttaattct
      841 tgtatatgag gatataactc ctcattactt actggtctta ttaaagattt aaatttatca
      901 atattttttg ttttttcatc atacataact gctccgattg caattatatc agaattaaat
      961 actgctcttt ttgatttaga atttggcata ttcatttcaa aatctatata tactcttttc
     1021 aatataaaca ccctttccaa ttgtttatag tgattctttt taactatttt tattcaaaat
     1081 tttctaagaa agaatgtttc tccccatctt tttgccaacc aagtactgaa tcaagattta
     1141 cattttctgc tgccttaaat atagattttt ctacattttt aaaatttgat tctaagctct
     1201 ttattaagtc ttttatctca tatcttttat tacctgtttt tttagcagca accatacatg
     1261 cacaatttaa tggccatata ccactatttt gaataaatct tataatatgt tcttctctta
     1321 tataataaag tggtcttata atttttatac cttcaaaatt agtagaatta agtttaggaa
     1381 gcattgtttt aaaatttcca gcacacaata agttaagcat tgttgtctct attacatcat
     1441 cataatgatg acctaatgca agtttgttac accctaattc ttctgccttt gaatataatg
     1501 ctcctctcct cattcttgca cacatatagc atggataatc ttttgctatt tcatctgcta
     1561 tctcaaatat tcttgaatca aataaatgta ttggtatatt tagatactca caattatcta
     1621 taagtaattg tcttatattt gcatggtatc cagggtccat agcaataaat tcaacatcaa
     1681 aattaacttg tccatgtttt tttaactctt gaaacatttt agccataaga atactgtctt
     1741 ttccaccaga aatcgctaca gctatcttat ccccttcttc aaccaattta taatctctta
     1801 ttgacttcat aaacttagac cataaatttt ttctatattt ctttattata cttttttcta
     1861 tatctcttac tggaagtctt tcctcaaaag gaactataat ttcacagcct tttcctgata
     1921 gttcactcat ctaatcacct cgtatattta tgtatattta tgttaataat attttacaaa
     1981 aaagtctacc ttcatccaca aaatactata atttttactt taattttact aaataattta
     2041 tagtttacaa taacacataa acttataata acataaataa cctctttctt ttattatctt
     2101 ttttattttt ctcatttaat attttattat tagtaacgat ttttaaatga ttgaatatta
     2161 tacactagat agagttacct atctatttac aacaaggagg ttttcatctt ggaaaataag
     2221 actagagata tcaaaaaaaa ttgtggtcca tctttggcta gaccatacat taataatcaa
     2281 attttcacag aaatgtactg cctttctgat gcattaaaat ttggaactat atttccagaa
     2341 ctaaacttac tagagtctga aatgtacaac aaagaattat atgctaagcc aaaaaaatat
     2401 agaggaggta gaagataatg aaagactcat ctagagctga acttatgaga aaagttcagg
     2461 aaacatcttt tgcatgtgtt gatatgaact tatatttaga caatcaccct gatgataaaa
     2521 atgctatcaa cacttataat tcattatgta atcaatttgc gcaagctaga tatgcttacg
     2581 aaaataaata cggtccttta actaactttg ggtatgctcc aagtagatgc ccttggcaat
     2641 gggctgacca accttggcct tgggacagag aatttaatta ttagacatca agtattggag
     2701 gattgaaaat tcatgtggat atatcagaaa actatacaac acccagttaa tataaaaact
     2761 tgtgacccta gaatggctaa atttcttata actcaatttg gtgggccaaa tggagaactt
     2821 gctgcatctt taagatattt aagccaaaga tatacaatgc ctactggtaa tatgcgtgca
     2881 cttttaacag atattggtac agaagagcta gctcacgttg agcttatatg tactatggtt
     2941 tatcaattaa cttctgatgc aagcccagaa gagttaaaag ctgcaggtct tggttcaaac
     3001 tatgctcaaa atggatatgg aatttatcca acagattcaa atggtgttcc atttgatgta
     3061 agacctatag cagttatgtc aaatcccgta accgacttac atgaggatat ggcagctgaa
     3121 caaaaagcac ttgcaactta ttatcaactt ataaacctaa cagatgacgt tgatgttata
     3181 gatgtattaa aattcttagg tcaaagagaa ataattcact atcaaagatt tggtgaagct
     3241 ttaatggatg cttacgagtt agaagaatct caaaaaatgt tctaaaattt ttatttgtat
     3301 aactattatt atttgataat ttataattta ctgttgtgtt aaaatttata aaaaatataa
     3361 atataattta ttttctataa acagagaaaa taaataaaaa gcaggtatca atcaaatagt
     3421 aacatgtatt atactataca ttactatcaa tattgtacct gctttcatat tataagcaat
     3481 aaagaaaaat ctatttatta ggttttataa taaaacaatt ataaaactct tcttgcattt
     3541 acatatctac ttgaatagta gctactattt atattagata ttgttacttt ttttgatgaa
     3601 cctgaagatg catgtatcat atctccattt cctatgtata ttccaacatg acttacagaa
     3661 ccattatttg aaccttgtgt atcaaagaat actaaatctc cacttctaag gtctcctcta
     3721 tttacatatg ttccatactt actttggtct ctagatactc ttggtatact aactcctgca
     3781 gattttttca taacgtactg tgtgaatcca gaacagtcaa aactatttgg accttctgct
     3841 ccccatacat atggttttcc aagtagtgtc tttgcaaaac ttattacact atcagctcct
     3901 tgacttggag aattagtcga ataagatgga attgaagtat caacagaacc tttttcagca
     3961 aggtattgac ttgacacata tccagtttga ttgccataac ttacttttgt ccatcctcca
     4021 ctttcagaaa tacttccaac ctcagtacca taacttaatg tagctatttt agaatgactt
     4081 gtacctggtc ctgttctaac gttcaatgac tttgctgtta caacctttgt accctttaca
     4141 aggtcatttg aactgttttc aacattttca tttgtagagt catttacact agttcctaaa
     4201 tatttacttg aaacataacc tactctacca ttagaactta tttttgacca tccatttgac
     4261 tcagatatgt atccgacttc agtcccatat cctagtgttg atattttaga actacttgta
     4321 cttggtcctg ttctaaaatt taatcctttt gctgttacaa cttttgtcga cttaactgaa
     4381 gtatcactac tttcattgct acttccaagg ctatttattg ctacataatt tccatgcaca
     4441 taacctgtgt ttccattata tttaactttt acccaagaac cttcttttcc tacgtactca
     4501 actttatcac ctttgtaaag tttccccatt gattcatggt ttgtacctgg tccttttcta
     4561 aaatttaccg cattccctgt tattgttctg ctttctatac tcacactctc tacttcagac
     4621 tcattagcat atgctaaatt ccccatagta ggcattatta tcgcagttgc cattatactg
     4681 gctgctattc tcttttgatt aaaattcata actttccact catctcctct tttctactat
     4741 ctttatttca cttcaaaata taaaagaaat aattgacact attaaaatat caattatttc
     4801 ttttatatta atattattac aaatttgtaa ctatttgtct atagtaatat ttgcttacca
     4861 taaattacca tgtataaatt ttaatcttca atagcctgta atttagtaat atagccatct
     4921 tttacctttt ttaaaaatgg ctatattttt taactttttt gtaacttttt aaaatccagt
     4981 tgagccaaac ccaccttttc ctctttcgga gtcacttaat tcttttactt cttctatgtt
     5041 aatatcatag ataggtttta ctatcatttg agcaattttc atatgctttt caaccttaaa
     5101 atcatttttc ccatgattta ttaatataat tttaagctct cctctgtatc cttcgtcaat
     5161 agttcctggt gtatttaata cagtaacaga atgctttaag gcaagcccac ttctaggtct
     5221 tacctgcgct tctgtcatag taggaagctc tatacatatc ccagttttga taagtttagt
     5281 ctctccagga ggtattacaa cctcttctat agaatacaaa tccataccag catcaccttt
     5341 gtgagcaaaa ttaggtatta tagcatcatc atttaatttt tttactttta aattgtacat
     5401 cttatatctc ctttcaactt tctataaata ttataactta aatttcgacc tcttgaagtt
     5461 ttttattttt ttgtggtaat ataattatta gtgttttaaa ggaggatttt ttatgaaact
     5521 tgtacttgct gagaaaccat ctgtggcaaa aactatagca tcatttttag gtgcaaagac
     5581 cagacaagat ggttactttg aaggaaatga ttatataatt acttatgcag ttggacactt
     5641 agtatcatta tatgatatga aggattatga taaagataaa tactctggct cttggaaaat
     5701 gaacaatttc ccatttgttc ctgaggataa gtttaaattt aagattgata gttctaaaac
     5761 taaacaattc aacactgtaa aaaagctttt gaatagaaaa gatgtagaat atgtaataaa
     5821 tgccactgac aatgaccgag aaggagaact tatagcattt ttaatatttt tactggcaaa
     5881 aaataaaaaa ccagtaaaaa gaatcttggt aaatgaatgg acaccagaag atattacaag
     5941 aggtataaaa aacctaaaag atgaatatga aatgagaaat cttcaagctg ctggatatac
     6001 taggcttatt actgactggt tgattggaat aaatttcact tctgttgcta cattgaaata
     6061 tggaaatggg aaactattaa acataggtag ggtaattctt ccaacagtta aattagtcta
     6121 tgatagagat atggaaatac taaactttgt tcctaaaact tattatgaaa tagaaggaca
     6181 ttttaaagct gaagctggtg aatataaagg taaatatgtt aagggtaaag aaagtaaatt
     6241 tgatacactt gaagatgcaa ataaaattat agcttcaatt acatctgaaa ctggtaaaat
     6301 actagataaa aaagttacta tgtcaaagga atatgcacca aaacttttta gtttgacatc
     6361 acttcaagga tatataactt ctaagtattc caattttaca tctgataagg ttttaaatgt
     6421 ctgtcaatct ctctatgagg gtaatggtaa gggtggatac ataacttacc ctagaactga
     6481 ttccattttc ttagaagaaa gtttggcttc aaaagcttct caaactttag ataaattaaa
     6541 ggttggtctt gaatatgaaa ataaaattaa attttctaaa actaaaagag tttttgattc
     6601 ttctaaagta gactcccata gtgctataat tccaacttat ataattccaa aaagtttatc
     6661 taaggatgaa caattagttt atgatgccat aaaagataga tttgtagcaa actttatgcc
     6721 tcctgctgaa tatgagaata cagaaattaa gactgaagta gataattgta ctttcttaac
     6781 aaaaggtaaa gtgcttaaat caaaaggata ccttgaggta tataataagg aagaaaaaaa
     6841 cgatttactt ccacttgtaa ataaagatga tgttgtagat gtgttagaaa taaaaccatt
     6901 aactaagcaa actactccac ctaaaccata tactgaggac acccttttaa aggctatgaa
     6961 aaattgtggt aaaaatgtgc ctgaagaaga tacaacagtg ctatctggat attcgattgg
     7021 aacatcagcc acacgtgctg atgtgttaaa gaagataagt caagtgggct atgtaaagaa
     7081 aaaagggaaa tcttattcta taacagacct tgggaaaaat ttagttgaaa tttttcctgt
     7141 taaagactta tttgatgtag attatactgg aaaacttgaa aaaagtttaa gcgatattca
     7201 aaaaggaaag tatacaagaa aagaatatct tactaatatc attagtttta tatatcaaaa
     7261 tgtcaatatt ataaaacaag atgcttcaaa aaatataaac acagaagcat atactttcga
     7321 ttcaaaaact aaaaaattta ctaaaacaaa agaaaaaaaa cagaaaaaag atgtaactaa
     7381 tactgaaaaa gaagttgcta tatcaaaaga ttctaataac aaaaaagaag ttaaaaatgg
     7441 tgatgaaaat caatctcttg gcaaatgccc catttgtcaa ggtgatgtac tagaatttga
     7501 caaaggcttt gcttgtaaaa atcataaaga atgtaaattt gttatttgga aaaatgataa
     7561 gtatttaagt ctttataaaa agaaagttaa caaaacaatg gtcaaaaata ttttaaaaaa
     7621 aggtgaaact aaagtaaaat ctttaactgc taaaaacggt aataaatttg atgctacatt
     7681 aaaatatgat aaaaatccag ataccggcta tttcaattgg aaaatagagt ttgacaacta
     7741 aatattcata agaaaagaaa tagcagtagt ataataatct atattatatt actgctattt
     7801 cttttcttat gaagttttaa cttttttaat agtgactttt acaatcacac tctaacctaa
     7861 tttctttact atttctgata actttaatgt atgttcatct aataaagtta gttcctcttc
     7921 agaaagatta gataattttt ttactagaga ttctttgaga atagctttta ctgcatcaaa
     7981 taatttaaat gctttatctg ttaattcaac cctaagaatc cttctatctt ttgggtcagg
     8041 aaatttattg actaaaccat gttccactaa tctgtcaata atcggagtca tatttgattt
     8101 taaaattcct aaattagaag ctatttgaga aattgatgat gaatttgatg tcataagata
     8161 aagaattacc ttagcatgtg atggagccat tggacattct tcaaaataag ctttcattat
     8221 atcagagtta ttttgaaact tttttaacaa atcgctttct ttaaatatat tattttcaag
     8281 cacaaataaa aaatctaaaa aagagtccgc tattttaagt atattgttgt tatccatatt
     8341 tgtaacatcc cttcaataga taatataata aaacattgtt gtttaatata gtataaatta
     8401 taaactatta ataaatttaa aacaagaaaa agttattgac tcataataat tataaattta
     8461 taatcaaatt agagaattat aaattgccaa taaagggaag ttttttaatt agtctaaaac
     8521 taaacttaaa ttataagaca ctttaaattc tacaacaagc tagtgtgcaa tatataatag
     8581 gaggagatat gaaaagatat ttaatagttt tcttaatgtg tagttcactg tttttagttg
     8641 gatgtggaaa aacaaaagaa tctgaacctg agaaaccaat agcagtttct gttcaaaaag
     8701 cagtaggtgg agaaattgaa aacacaaatt ctttctcagg aactacaaaa gttaaagatg
     8761 aaacagctgt tactgcacag actgttggca cagttcaaga agtgtatgta aaacttgggc
     8821 aaaatgtaag aaaaggagat gaattattga gtataagcag tccagagcta gaaaatagtg
     8881 taaagcaaag taaagcctca ctagatttag caaaagcaag ttattcaagt gccactggtg
     8941 gttcattaga ggcacaagta aatcaggcaa aaacagctct tgacaatgca aagattcaat
     9001 atgaggagtc tcaaagaaat tatgacaata ataagattct ttatgaacag gaagtcatta
     9061 gtttagacca atttaaaaaa atagagtttt ctttagagca aacaaaacaa cagttagatt
     9121 ctgctcaaag agcatacgat acagcaactt caaaaagtat acctcaagct aaagcacttg
     9181 ctaaaaaaca gcttgaccaa gctcaagtat catataattt agcaatgagt aatttagaca
     9241 aattaacatt aacatctcca gtagatggta caataacagc taaaaacttt gattcaaagg
     9301 aaatgataac acaatcacaa ccagctttta ttatttctaa tcctaatata ctagaagttg
     9361 atttaaatgt agcagaatca gatataggta aatttaagaa agatggaaat gtagatgtta
     9421 taattgaaga ccaaaggatt ttaggaaaaa tagattatgt accttcagta gttgaccctc
     9481 agacatcttt atatcctgtt aaagtacttg taaataatgc aaacaacaaa tttaaggcag
     9541 gtatgtctgc acaagtaaac ttaagtattg aaaaagaaaa tggtgctgtt acagtgccta
     9601 aaaaagcaat atttgaagaa aatggtaaaa aatatgtata catagcaaca aaagacaata
     9661 tagcaaagaa acacttggtt caaactggaa ttgtaacaga ggataaaata gaaattaaaa
     9721 gtggtgtaag tgataaagat acagtgatta ttggaggaat aagtcttatt tctgacggaa
     9781 ctaagatatt tcctgtagaa aaggagaagt agactatgaa tttaacacag acttccgtta
     9841 aacgtcctct cacaatcata atggtctttt tagtattaat agtttttggt ggtattggat
     9901 ataaaaaaat gtcaataaat ctaatgcctg atatagaaat accagttgta atggtcatga
     9961 ctacttggac aggtgctggt cctcaagacg ttgatgaaca agttagtcaa aaagttgatg
    10021 aaagtttatc tgccgtttca aatgtaaaat ctactatatc aagttcacaa gaaagtgttt
    10081 ctatggtagt tgctcagttt gaatttggaa ctaatttgga tgaaataatg aatgatgtta
    10141 ggtctaaagt tgatgcatta cagaccagcc tcccagatga tgcagcaaaa ccaacagttt
    10201 taaagctgga tatgaatgca caggctatag gtcaacttgt catatctgga ggaaatgaaa
    10261 atagttcaca agccttaaga aaatacgctg aagatgtaat tcagcctaaa atagaatcca
    10321 tagatggtgt tacttcagca gaccttaaag gtggagaaaa agcacaggtt aatgtaatag
    10381 ctgacccagc tgttctttca aattatggag ttagtttatc cactataaaa ggtgtcttat
    10441 cctctagtaa taaaacattc ccttatggtt caattactca aggtgaggat aaaatagttt
    10501 taagagcaat tgataaatta gaatccctag atgatataaa acagattcaa attcctgtaa
    10561 aaggaggaaa tacagttaga ttagataatc tttgtagtgt agattatgga tatgcagaca
    10621 aagatagtat ttatagatac aatggaaaag acagtttggt aatagatatt tctaaacaac
    10681 aagatgccaa cactgtaaaa gttatgcaga gtgcatacaa atacgtagat gaattgaata
    10741 aggaaaatcc tcaatttaaa attaaaattg ctaatgatac aagttcatac ataagtgaat
    10801 caataaacag tgtaatgagc aacttgctta taagtgctgt tatcgcattt attgtaatat
    10861 ttgctttcct aaaaagtgta agagcttcac tagttgttgc agttgcaata ccaatttcta
    10921 taataggtgc tatagcaatt ctctacttta ctggtgaaag tttaaatctt attactgcaa
    10981 gttcattggt aatttcagtt ggtatggttg ttgataatgc tacagttgta attgaaaata
    11041 tatttaaata taggaaaagt ggcagattga gtcttgatga ttgtgctatt gagggaacaa
    11101 gaactgtaac aaatgcaata cttgcatcaa cattgaccac gatagcaata ttcttaccta
    11161 tcatgtttac agaaggtata gctaaaataa cttttggggc attaggtaaa acactaatag
    11221 cttcactagc attctccttt ataggtgcaa ttacactcgt tcctagtgta tttgcaaaat
    11281 taagcagagg aaaaaatagt caaaagatgc aagaaaaaga tagtcctata tttgataagg
    11341 taagtgaagc atataaaaaa ttattaagtg tatgtttaag acatcaacgc ttagttgtaa
    11401 tatcaagttt acttattttt gtagcttcct tatttggaat gggatttata ggtatggact
    11461 ttatgcctgc agcagacaag ggtgaattat ctatttctat agaacttcca aaaggtctta
    11521 gcctagaatc caatgattac tatgtatcta tgactgagaa aaaagtctca gatattccag
    11581 aaattaaaac tttaataaca actttgacat cagattcaaa taatagtaaa gcaagtatag
    11641 caattgaatt agaatctcaa aaaaatagaa aaagaactac tgatgaaata gaaaaagaga
    11701 taattgatag agtggctact gtaccagatt gtaaaataaa tgtaagtcaa aacagtagtg
    11761 ttatgggtgg agctggagga gcagacttca cattagaaat gaaaggtcct gatttagatg
    11821 tattaaaaat actgggaaaa gaagctgaaa aagaatttag ctctataaaa ggatttagaa
    11881 atgttgaaac ttctcttaca gatacaacac aagaagctca atttactata gataaacata
    11941 aggctcaaga atatggtgta aatactgctg aaattgcagg catgttacgt acagcaataa
    12001 atggtgactc cgtaaccact gctactattg atgattacaa agtggatgta aacctaaaat
    12061 ttaaagcaga tactattgat agcttagaag atataaagca actaaaagta aactctgcaa
    12121 ctggaaaaga agttcctctt ggtgcttttt cagatataaa aatggcagat ggtctacaat
    12181 ctatatctag gactgatgga gatttttctg taaatataac tgctacactt gacaatttag
    12241 atgctggtac tgctacaaaa ctagcactag aaaaaacgaa taaaatggta attcctaaag
    12301 attactctat aggtgttggt ggtgaaacag aaatgatgaa tgaatctatg gcaagtcttg
    12361 gattttcaat ggtcatagct atagcattag tttatatggt aatggtagct cagtttgaat
    12421 catttagtaa accatttata atcatgttct gtgttccatt tgcattcgtt ggagttgtgc
    12481 tttcgcttct agttagtggt caaagtttaa gtactgtcgg tatgctaggt ataatcttac
    12541 ttatcggtat tgttgttaat aatggtatag ttcttattga ctacatagag caacttagaa
    12601 aaacaaatcg taacaatgat ttaattggtt tggtttcaat tggttgtgca gcaagattaa
    12661 gaccagtctt aatgactaca gcaacaacaa ttttaggtat gttgccaaca gcactatctc
    12721 ttggtgaagg tggagaaact atgcaaccac tagccatagt tataatgggt ggtctaactg
    12781 tatctacact tataactttg gtgcttatac ctactatata cttaatattt gataaatggg
    12841 aaaataagtt ttcagacaaa atgcctaaaa tatttggtaa gataacagat aaaataggaa
    12901 gtataaaacg taaaataata aagaaaccaa aattgaaagc taaagtttaa atagaatgga
    12961 gggtgattgt attgaataaa aaaatgagca aaatagttgc aattggctgt ggtgttggta
    13021 taataactgc caatttaatc ccagtttacg cagataataa tacttcttct ataaacaacg
    13081 ttgataattc tattttaagt gactcaaata aaagaacatc tgaaaaggaa attttgactg
    13141 ctagagaagc tgttagtgct gcacttaaaa atagtgaaaa attaaaaatg aaatcagaag
    13201 aaataaaaat gttaaaagaa aagttagaag tacaagatga gtttgatagt tttactggaa
    13261 gtgacaactc gtttccatac gaccaaattg gacttcttaa aaatcaaagt gaacaggcta
    13321 aaggctttat ggaggaccaa atagcaaatg atattactaa taaatttaac gatttagttt
    13381 caagagaaaa tgagctagat aagataaaaa acaatcttga aataaaaact aaagaaatta
    13441 aagatatgaa attaaaaaaa gatttagggt tagtaacatc tttagaaact gaatcagctg
    13501 aacttgaact tcaaacacta caaaatactc aaaaagctaa acttcaagaa ctaaaaaaca
    13561 atcaagacta ttttaagtta ttgactaata tagatttaaa taattatcaa ttggataaag
    13621 aatatagatt tgaatctttt agagtaggtg gctcagttga ttcatatatg gaaggtaagg
    13681 ttaatgaata tttaaaatac gaccaattga ttttagaacg tacagaagaa agctttaatg
    13741 ataaagatga gaacaaagca gatttaccag atagacctaa tcttacaaga ccagttgctc
    13801 ctacaaaacc agagcaaggt aacctaactg atgatgaata caaggttctt atggataagt
    13861 atgaaaaaga ctacaagaga tatgaaaaag aagttgaagc atacaatctt gaaagacaga
    13921 cttatgctgc tggccttact acttatgcaa attatcttca acaaaaattt aataccgaaa
    13981 atggtctagt aacattagaa gacagtaaaa aagctcttaa aaaagggtta attgatagct
    14041 atgctcaatt acttgcttta gaagatacaa ttcagattac taaaaaacaa cttgatttat
    14101 cagaaaaaca attaaaaaat actaaattaa gatatgattt aggattaatt actctaactg
    14161 attataaaaa acaagtggta agtaatcaag atgctaaaaa tagctatgac actcttattg
    14221 tgaattataa ctcactaaaa aatggtatag aaaaaccttg gatacttaat actggaaaat
    14281 aattctggta aatagaaaga ttactttaac atacgtttga ttaaaaaata gttatgcaca
    14341 ctcgtggctt tagtcatgga agattcagaa ggcaaataat agaaatagat tagtaaaaat
    14401 atatttactt ataaaactgt atacttttat agaggct
//
LOCUS       DAEQJM010000084        14403 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.085, whole genome shotgun sequence.
ACCESSION   DAEQJM010000084 DAEQJM010000000
VERSION     DAEQJM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14403
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.085"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            1133..2491
                     /locus_tag="KRQ43_003193"
     CDS             1133..2491
                     /locus_tag="KRQ43_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH2743533.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     ASGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            2597..3391
                     /locus_tag="KRQ43_003194"
     CDS             2597..3391
                     /locus_tag="KRQ43_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH2743534.1"
                     /translation="MVTIKEYSIPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            3384..5690
                     /locus_tag="KRQ43_003195"
     CDS             3384..5690
                     /locus_tag="KRQ43_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH2743535.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVAESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRIIRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            5829..7106
                     /locus_tag="KRQ43_003196"
     CDS             5829..7106
                     /locus_tag="KRQ43_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH2743536.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIESLKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            7289..8011
                     /gene="yqeC"
                     /locus_tag="KRQ43_003197"
     CDS             7289..8011
                     /gene="yqeC"
                     /locus_tag="KRQ43_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBH2743537.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            8118..8687
                     /gene="mocA"
                     /locus_tag="KRQ43_003198"
     CDS             8118..8687
                     /gene="mocA"
                     /locus_tag="KRQ43_003198"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBH2743538.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            8684..9703
                     /locus_tag="KRQ43_003199"
     CDS             8684..9703
                     /locus_tag="KRQ43_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HBH2743539.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            10041..11666
                     /locus_tag="KRQ43_003200"
     CDS             10041..11666
                     /locus_tag="KRQ43_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2743540.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            11865..12341
                     /locus_tag="KRQ43_003201"
     CDS             11865..12341
                     /locus_tag="KRQ43_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743541.1"
                     /translation="MVKKRLVAVVLSLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQPNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(12549..13661)
                     /locus_tag="KRQ43_003202"
     CDS             complement(12549..13661)
                     /locus_tag="KRQ43_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH2743542.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            14002..14379
                     /locus_tag="KRQ43_003203"
     CDS             14002..14379
                     /locus_tag="KRQ43_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH2743543.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
BASE COUNT         5652 a         1503 c         2547 g         4701 t
ORIGIN      
        1 tgaaataagt aaaattttat caatgagaac ataaaaattt tatactatac aaatgtatgc
       61 aaatattggc actaaaattg ctctataaaa attataaata gtaatatgaa taaaattttt
      121 actataaaaa taatattact attttgctta tagatatata tatctataaa tagatagaaa
      181 cttgtatatt ttatgttgca gatacaaata tagtaaagga gagtacattg gtacaactga
      241 gatacatagc ttattaagtt tttctgtctt atgagaatta tattataaaa tattcataaa
      301 tattttgagt ttaaattaaa taattatttt atgcttagat taattgatat ttaattaatt
      361 taataacaaa aacagtgaaa gagtaaataa tattatttac agggggtaaa gcaaagtatg
      421 ttaaataaat tgtacttttg gccccgtaca tagagaaatc tatgtaggac acaactttaa
      481 aaccagtaaa tcctaaagcc ttgcaactac aataaaagat agaaagaaac ttttatgaat
      541 gtggtgaaaa ccagaaacaa tagtgaggat ggtatatggt gagagcctaa gtacttaaaa
      601 atggacattt ggtcgccaag cctagaaata ggaaggtcaa acgactatct cgagagagag
      661 tacactataa gcgattgata gtggaaacgg gttgctctta gcaggtaatg ctgaagatga
      721 agaaatagtc tacgctcata tgaaagtatg aggtcactag atttgaagtg acatctataa
      781 agtagcgttt ataggtaaat gtttaaaact tgaaacatgt aaatacttat gaaaacttat
      841 aacttataat gattaagatt gaaagattta aattgaatta aatttactat aaaaaattaa
      901 aaattcatag ctataatact cttatatttg taaagcatgg tatataatgt atacaaaatt
      961 aaagaatacg tgtatttgtt aataattaaa tttattgcat ctgtttttta agactaaaaa
     1021 cttaaatata tgttggagta tagttgatat ttatgaacat cattaattta atatattaga
     1081 tttttaagta tttatataat tcaataagtt ttatgtaacg ggagttttta ttatgaaagc
     1141 aaaaagtaca tcaaaatttg aattagacgg aataccacca ctaaaggaag caataccttt
     1201 agggttacaa cacttaatgg caatggtaat aggtagttgt ttaccagcga tattgattgc
     1261 aaatgcatct ggacttaatc ataagatgtc aacattattg attcaagccg cattagtttt
     1321 tgcaggatta tcaactttat tacaattata tccaatacct ttgtttaaag gttttaaatt
     1381 aggaggagga ataccagtta taatgggagc tacagctatg tttataggag ctggggtatc
     1441 tgttgcaagt aagtatggac taccagtatt atttggctct caaataatag ctggtatagt
     1501 aataattata attggttttg gtcttaaaaa aatacgattt atatttactc cagctgtatc
     1561 aggaacaata gttgcatgta tgggtcttgg actttttcca atagctataa aaaacttagc
     1621 tgggggtatg ggcaatgaga cttttgggaa tccaattaat tttatagttg gaatatctgt
     1681 atctcttatg atattaggat taaataagta tggaaaagga ttatttaaag atgcatcaat
     1741 attagttagc ataatttttg gatacatttt atcattaatt ttgggtatag taaatttttc
     1801 ttcaattcag gagtttactt tggttgcgct tccaaaacca cttgcttttg ggctagatat
     1861 aagacttgaa gttgttgtaa tgttttcaat aatatattta gttgagatag ctgatataat
     1921 gggtgcttgt acactttctg cggtaggagg gcttaataga caagtaacag atgaagaact
     1981 ttcttctgct gttttaggaa atggagtact ctctacaata ggtgcattat tttctgcaac
     2041 tccaatgggg atgtttggac aaaattctgc aatcgtttcc aatacaaagg ttgtaagtaa
     2101 atttgtacta gctattggag gaattggatt atttttggca ggaatatcgc ctttattagc
     2161 taatttaata agaacaattc ctccctgtgt ggttggagga gcaacactcg ttatattttc
     2221 aactcttaca acatctggtt taagacttgt tagtatggat ggatttaatc aagaaaatag
     2281 catgatatta ggtctttcta tggcttctgg tattggattc atggtagctc ctcaagttct
     2341 tgaaaaattt ccaaaattta tagagacatt acttgcagat tcaagtgtag tttcaggagc
     2401 aatggtagcc ataataattc aagctttata tatggtaaaa tttcctggaa ataaaagtga
     2461 taaggttgag gataaaaata aaagtttata atgtaaaggt ttaatatatg tgaattaaat
     2521 atactacaat tataaatata aataaaagat ttattaaaaa cttttgtgtt ttaataagtt
     2581 aatgatgggg gataagatgg ttactataaa ggaatattca attccacaga gtttagaaga
     2641 agcatataaa attttaattt ctaaaaaaaa taatgttatt ttaggtggat gtggatttat
     2701 aaaattaagt aataaaaata taggaacagc gatagattta aaagatataa atctaaatta
     2761 tataaaagag gatgaaaaaa atattttgat aggtgcagat acttcactta gaagtttaga
     2821 aattgataaa actataaaaa attactgtag tggaatactt tcaagcgctg tttctaatat
     2881 agttggtgtt caatttagac aaggggctag aattggtgca agtgtatttt caaagtatgg
     2941 cttttctgac ttaataccag cgcttttggt tgttggagcg aaggtgagat tatacaataa
     3001 aggaatacta gagttaagtg agtttttgga tagtgaatta agtagggata tattggtcga
     3061 agtaatacta ccaaaaaaag atgcgatagc tgtttttgac tcaataagaa aatgcacagg
     3121 agatttttct gtattaaatt cagcaatgct aaaagaaaat gatacttaca aaatagcaat
     3181 tggggcaaga cctcaaaaag ctagattagc acttgaagcg agtaatatat taaataaaga
     3241 aaaagatata gataaggcat ctattgttgc tagtaaggaa cttacttatg gaagtaatat
     3301 gagagctagt aaagagtaca gaaaggatat ggcaagtgca ttagttaaaa ggatgtataa
     3361 tgctattgag gagggaatgt ataatgatta ataaggggat aagaaagata gatagtacag
     3421 caattgtcac aggaaaacct ctatatactg aagacctcat tatgcataaa gatgttttga
     3481 cattaaaact acttagaagt ccacatgctc atgctaagat aaagaatata gatacatcaa
     3541 aagccgaaaa aattccaggg gttgtgggta tttatacgta taaagatgta ccacaggtca
     3601 gatattgtgt gccaggtcaa acagaaccag aagcatcacc ttatgataga gttttacttg
     3661 aagatacagt tagatttatt ggagatgaag tagctttagt ggctgctgaa gatgagaaaa
     3721 cagcacttaa agccttaaaa atgataaagg tagattatga ggttttaaag cctgtgtttg
     3781 atgcaagaga agcagaagga aatgaagttg ttatacatcc agaaaaagac atagtagagc
     3841 catacccttt tggattggat gcaaaaaata atatagtatc aaaagaattt tttgaatttg
     3901 gagatgttga agctaagctt aaagaaagtg attttgtggc tgaatcttca tacaaaaccc
     3961 aaagtcaatc gcattgcatg atggaaactc ataggtcata ttcatataaa gatataaatg
     4021 atagaattgt tgtagtttca tcattacaat caccacacaa tgtaaagaga ataattagaa
     4081 aagtattggg tataccatct tcaaaaataa gagtaattaa acctagaata ggtggtggat
     4141 ttggaggaaa gaatatagca gcaacagata tatttactgc atttgttact atgaaaactg
     4201 gtagaccagc aaaatttgta tttacaagaa gtgaaacttt tgtaggttct aatagtagac
     4261 atgaaatgtt ttttgatgtt aaagttggtg cagataaaga aggaaattta aaagcaatag
     4321 agctaaagtc attaaacaat acaggtgctt atggtgggaa tggtgtctct gtttcttccg
     4381 aatctggaca caatacctta ccaatatata atgatattga tgctgttaga tttaatgcta
     4441 gaacagtata tactaatagg ttaccagcag gagcacttag agggtatggt gctacacagg
     4501 gaatatttgc aatagatagt gctattgatg aattggcaca taagattgga atggacccac
     4561 ttgaatttag aattaaaaat ataatagata ggtataccaa tggaaaagca gctgaagacg
     4621 aaatattaag ttgtgagctg agacaatgta tagaaaaggg caagaaatta atcaattggg
     4681 atgataaata tccatgtaaa gatataggaa acaacaaagt aagagcagta ggtatggcag
     4741 tagcaaatca tggttctggt ataccgcgtg tagatatggc aacagtcact ataagaatgg
     4801 atgaagatgg cacatataaa ctattatctg gtcttgctga cttaggtcaa ggggctgata
     4861 caattcaagc tcaaattgct gcggaagctt taaatactac tgtagataga atttctattt
     4921 atacaggtga ttcagattta tgtccctatg atacaggagc atttgcttct tgtacaacaa
     4981 cggttacagg aaatgcaaca ataaagacag caaataaatt aaaagatata ttactttcag
     5041 ttgcagagtc aaagctagga tttaaaaaag aagatttaga gttgggaaaa gacagggttt
     5101 ttgttaaaaa cgataatagc aagtttgttc tattagagga attgggtaga gaatctgttg
     5161 gaggaatagg atttgctagt gatgatgtac cagtagtttt ggaagcaaca gaatcttttg
     5221 gcatgttgaa aaaaataaaa ccatttatag caggatttgc agagatagaa ttagataaaa
     5281 atacaggcga atataaggtc ataaattttg catgtgtacc tgattgtgga acagttataa
     5341 atccaacttt agctagaata caagtagaag gtggtgtgat gatgggtata gggtttgcaa
     5401 tgtatgaaga ccctatattt gataaagatg ggagattatt aacagatagt ttcctacagt
     5461 ataaagttcc tacaaaaaaa gaagttggaa atatattggt agattttgct gagaatttcg
     5521 acccaggagg tccttatggt gctaaatcat taggagaaat agttatacat acaccagcgc
     5581 cagctatagc aaatgcaata tttaatgcta caggagttcg tttaagagag cttcctatga
     5641 cttttgaaaa agtttatatg ggtatgaaaa ataataataa acaattataa taaataataa
     5701 ggtgtataaa agcaagtaaa tttaaattat tttgtaaaat aaagtaatta aatggacatt
     5761 atatatggtg ttttgtaaaa ataccgtata taatgtctag tagagtatat tctaaaggag
     5821 gtgagttcat gtcaaacaga ataaaaaata tacactatgg aactcagaga caacaattaa
     5881 aaaacttaac taaaaaagaa tatcaagctc tacgagagat gtgcttctta gctaagaact
     5941 tatataatgt tggtacatat aatgtaagac agcattattt caatcaagga gaacatctta
     6001 actatgaagc taattatcat gtatgcaaag aaaatgagaa ctataagctt ctcaatagta
     6061 atatagcgca acaaatatta aaagaagtag acagttcgtt taggtcattt tttgggttaa
     6121 ttaaattagc caaagaaggg aaatatgact ttagagggat aaaatcacct aaatatttag
     6181 ataaagaagg attttttagc ataataatag gtcaaataag aatcaaagaa gatgggattt
     6241 taaatgtacc tatgtctcca gcatttaaaa aactatatgg gaaagtaagt ataaaagttc
     6301 cacaaaatat actagagaaa aaaattaaag aaataagaat aatacctaaa cataaagcta
     6361 ggttctttga aattcagtat tgttatgaaa taccgaaatc agaggaagtt tcaaatcaaa
     6421 aaaatgcact agctatagac ttgggtttag aaaatttatg tacatgtgtt accaatttag
     6481 gtgatagttt tatcatagat ggaaaaaggc taaaatctgt gaatcagtgg gcaaacaaac
     6541 agaatgataa aatagaatcc ttaaaattaa aaaagaatat aactgcaata acaagaaaac
     6601 aatttaaagt ttggaataag agaaataatc aagttaaaga ctatgtaaat aaaacctgtt
     6661 tttatataat tgattattgt gtaaaaaata atattggaaa tttaattgta ggatataatg
     6721 ctaagttaga aaaaagtgat aatatggaga gaaaaatata tagaaatttt ataagaatcc
     6781 catttggaga gataaaagga aaattagaat atctatgtaa aataaaaaat atcaatttta
     6841 ttaggcaaga agaaagctat actagtaagt ctgatttttt tgctgatgat tttctacctg
     6901 atatcaatgt ggacaatgtt aaaaaatatg actttaaagg ggaaagaata acacgtggac
     6961 agtacaaatc cagtgttgga atcattataa atgcagatgt aaatgcgagt cttaatatac
     7021 taaaaaaatc acaagtagtt aatttatcta atttacagaa taatcctcaa atattaaagc
     7081 aaccacagag agtaagaata tcttaattat atttaaaaga taaactgata gcgtaagctt
     7141 acagcttagc ggcgaattgg atccgccttg ttgtttacaa cagaatctat ttactttcga
     7201 gtttatggaa tttcaaaaat cacttttact aaaaaggtct aactataata attaagagat
     7261 tagaaaactg gttataagag gtgaaagtgt ggaactatca aatataatag aaaagaatga
     7321 aataataact gtagttggag caggaggaaa aacttcgttt ataaactatt ttgcaaattt
     7381 ttatagagat aaattgaaag ttcttcttac aacaacaact aaaatatatg taccaaacga
     7441 ttatgacaat ataattatta caatagatgg aactgttatt ccatctattt gtcatggaat
     7501 aacagtctgt ggcagttata taaataatga aaataaatta gtaagtattg attcctctat
     7561 tttggatgaa attgtagacc aatttgattt agttttaata gagggagatg gctcaaagag
     7621 aaaaaaactt aaaggttgga atgctaaaga accagtagta tatcataaaa ctacaaaaac
     7681 catagggata ttagatataa catcatttgg aatgaatatt aatgaagaga atatacatag
     7741 agtagaaata tttaaaaaaa tagcaaattt agatacaagt agtattaata gtagttctac
     7801 agtaagtatt gaaaacttaa aaaatatagt attaaatcca aatggattat ttaaaaatta
     7861 ttctggaaaa agagtattat ttattaataa agttgaaaat gaaaaatata aaaatttagc
     7921 tataaaatta atagaaaata ttaaagaata tgaaagtgaa atagagatat tttatggaag
     7981 cgtaaaacaa aaattttgtg taagatattg aagtattaaa atagtttata tgatattata
     8041 tatatagata atatcaatag agatattata aaaatcatag aactatcaat atattataaa
     8101 taccaaggat gatatatatg ataaatgcag tgataatggc atcaggcttt gccagaagaa
     8161 tgggagcaaa taaactttta ttaaattata aaggctgttc tataatagaa catgtattta
     8221 gagaagttag caagattgat tttcatcaag ttgtagtagt aagtcaatat gaagaggttt
     8281 tgttattgtg taataaatat ggttttgaat atatagataa taaaaatgca aatataggtc
     8341 aaagtgaatc tataaaatta ggagttttaa atagctcaaa atgtgatggt tatatgttct
     8401 ttgtaggaga ccagccattt attgataact tatatataga taaaattata aatactttta
     8461 aattagatag agattttata gtaattccaa gatacaaaga tatgtgtgga aatccagtca
     8521 tattcccata tagtaagaaa gaagaattgt tggcacttaa agaagatgaa aaaggtaaaa
     8581 ccattttaaa aaattcatca aaaataaagt atgtagaagt tcctaaagaa atgttatttg
     8641 atatcgatac aaaaatggac tatgagagaa tcgggggtaa attatgaagc taataaaaac
     8701 tatagatgct gttggacaag ttttatgtca cgacataact caaataatac ctggagaatt
     8761 taaaggaaga aaatttaaaa agggtcacat agtaaaagaa gaagatattc cagtgttatt
     8821 atctcttggt aaagataatt tgtatgtatg ggaaaagtca gaaggaatgg ttcatgaaaa
     8881 tgaaggcgca ttgtttttaa aagaactaac tgctggagaa aatttagatt ttagtgaaat
     8941 aaaagaagga aaaatagatt ttatagcagc atgtgatggt ctattaaaga tagatgttga
     9001 tgcacttttt gatttgaatt gtgttggaga aataatgatg gctactcttc ataataattt
     9061 tatagtaaat aaaggtttaa aagtagctgg aacaagagtg atacctttgg ttatagatga
     9121 gaaaaaatta gaagatgcaa aaaaagtagt tggtaataga aaaatagtaa atgtagtacc
     9181 ttttaaacct aagaaagtag gaattgttac tacaggaaat gaagtgtttt atagcagaat
     9241 tgttgataaa tttggaccag taatagaaga aaaagtaaaa ggctttggtt gtgaagttat
     9301 aggacagact atatgcccag atgataaaga aattataaag agtgcaataa aagaatttat
     9361 aagtcaagga gcagaactta tctgttgtac tggcgggatg agtgtagacc cagatgatgt
     9421 tacgccaaca gctataaaag aaactggagc tgatttagtg acatatggtt caccaatatt
     9481 accaggagct atgtttttac ttgcttatta tggagaagtt ccaattatgg gtataccagg
     9541 atgcgcaatg tatcataaaa ctacagtatt tgatatagtt ttatctaggg ttttaattga
     9601 tgaaaagctt gataagtatg atatagctag atatggtcat ggtggccttt gtatgaactg
     9661 tgatgtatgt acttatcctg catgtaattt tgctaaaata taaagttatt aaaaaagagt
     9721 atttacaaat taagtactct ttttaaatat gaaacaaaac agctagaatg atgttttaag
     9781 aaaagcatat ttatttagaa attataataa cttattttca atgtgtaaaa gaatgaataa
     9841 agttgcaatt tgatttcttt ataagtataa tataagagat tgttaatttt tataaattta
     9901 caatttttag tattatttta ataaatattt cacaaattta gtataaaaaa tatactattt
     9961 acgtgataat atataataaa aatgttatca aagttttatg ataaaataaa ttatgagcaa
    10021 aaagaaagga aaatatatta atgttacaag ttacaggtgt tggacttaga tttggtgata
    10081 aggaactatt taaagatgtt aacttaaaat tcactaaagg taattgctat ggaataatag
    10141 gagctaatgg tgcgggaaaa tctacttttt taaaaatatt atcaggagaa atagagccta
    10201 atacaggtag tatatctata actgataaag aaagaatgtc agttttaaaa caggaccact
    10261 ttgaatatga agaagaaact gttttaaatg ttgttataag aggtcatgag agactttgga
    10321 acataatgaa agaaaaagat gcattgtata tgaaggaaga ctttaatgaa gaagatggga
    10381 taaaagctgc cgaacttgaa ggtgagtttg cagagcttga cggatgggat gcagaaacta
    10441 atgctgagaa aatacttatg ggtcttggca taacgaaaga tatgcattac aaacaaatga
    10501 aggaactagt tggtggggaa aaggttaagg tattgttagc acaatcactt tttggtaagc
    10561 ctgaaatact attaatggac gaacctacaa accacttaga ttttaaatca ataaactggt
    10621 taaataattt tataatggat ttagaagagt ctatagttat aatagtatca catgatagac
    10681 atttcctaaa tcaaatatgt actaatatag ttgacgtaga ttttggtaaa atacaaatgt
    10741 acgttggaaa ctatgatttc tggtatgagt caagtcaatt ggctttacaa ctggctaagg
    10801 accaaaataa aaagactgaa gaaaagatag ctcaattaaa ggaatttata gctagattta
    10861 gttctaatgc ttcaaaggct aaacaagcaa catcaagaaa gaaacagtta gagaaattag
    10921 aagttgaaga tatacaacca tcaagaagaa gatatccata tgtaggattt acacctgcaa
    10981 gagaaattgg gaatgaagtt ttagaagtac acaatttaac taaaactata gatggggtta
    11041 aggttcttga taatgtgtca tttagattgg atagagatga taaagtagta tttatgggag
    11101 atgaaatagc tactactgca cttttcaaca tagttatggg agaacttgaa ccagacagtg
    11161 gagagtataa atggggagta actacttctc aagattatct tccaaaaaat cataataagt
    11221 tttttgacgg agtagaatat tctttggttg actggcttag acagttctct gaagaaaaaa
    11281 gtgaaagttt tataagagga tttttaggta gaatgttatt ctcaggtgaa gaagcattaa
    11341 aagaagctca agttatatct ggaggagaaa aggttagatg tatgcttagt aagctaatgc
    11401 tttcaaatgc aaatgtactt gtattagatg accctactaa ccacttagac ctagaaagta
    11461 taacttctgt aaataaagga cttgaaaagt tcccaggagt gcttttattt acttctcatg
    11521 accatgaatt tatatctact atagcaaata gaattataga gataactcca aatggaataa
    11581 tggatagaaa aatggacttt gatgagtatt tagaaagtaa agagatacaa gaccaattag
    11641 ctaaaatgta tggaaaagat aaataattat tagtataaaa ccttttaata tttgatacat
    11701 gctatgcatg agtgtgtaaa tttttaatca aatattagga ggttttttat gttgtttaaa
    11761 tatgtttatt agcagaatcg agtaatattt tgtatattaa gaatttaaat ataatatagt
    11821 agatgatata ataaaaatat ataacatttt ggggggaata gattatggtt aagaaaaggt
    11881 tagtagctgt agtattgagt ttagctatga ttagtgtagg gaatttttca tatgctcact
    11941 caggagggca taattcatca ggaggtcatc ataataaaaa taaatcagag ttaacacgtt
    12001 attattgtgg aggacattca gcacatcaac caaataaagg tttttgtcct tatgctagta
    12061 caaaagaaaa ttctggagta acaatatctt cagtacataa cgaaaaaaat cataaaaact
    12121 attttgcaga aaaagggtat aataaaggtt atgaagatgg gtgtaaaggg ctttataatt
    12181 taagtgtcac agaagccaaa tctgataatt tatatgaaaa agagatttta aaaagttcat
    12241 atgaaaaagg atatttaatt ggatacaatg aatataaagc aaaaaaagta gatgatgtaa
    12301 tgaagaagat gttagatatt ccaatgttag caagtatata ataaaatagt atttaaaaag
    12361 atactttcta taaggaaata tcttttttat tgtaaagtat aatttttcat aaaaaagtat
    12421 aataactgag gcgataaatt aaaataaaac agattattta agtagttatt aatttgagat
    12481 agatacattt aatattaatg aatctatctc aataagctaa gctaatttaa agctaagata
    12541 aattaatatt aattagcatt aaataaactt tcagaaattt tgtcagaagc ctctttatcc
    12601 atttctttaa gtacatgaga ataaacgctt agagtagtac ttatatttga gtgtcctact
    12661 ctctcggata taacctttat aggtacttta gaatttataa gtaaagtaac atgtgagtgt
    12721 cttaaatcat ggaatctaat atgaggtaat tcattctttt ctaaaaatct tttaaatttt
    12781 ttactcataa catcttcagc aataggttca catttcttat tgaaaaacaa caaattatta
    12841 ttatttctaa tggaagattt taataaattt ttattctgtt ttattttata ttcttttaat
    12901 aaagacatta attctttggg agaagatatt tttctaacag agctttctgt ctttggctct
    12961 ttgagaataa cagaaccatt aattcgggaa gttatcttat ttactgttat tgtattttct
    13021 tcaaaatcaa tattatccca agttagacct aaaacttctg aaattctaag acctaatcca
    13081 atagccaaat taataggtaa ttccatttct gtattttttg ctaaatctaa taattttatc
    13141 atttgttctc tatcataaat ctcattttta aattttttat atcttggagc ctctatacta
    13201 tccataacat tttcttttat taatttgagt ctataagctc tttttattgc aagtttcaat
    13261 atatttatat gaatcttaat tgattgagga tttagtttat aagatagttt atctatgtag
    13321 ttttgtatgt gaaccggatg taagtcttgt attttatatt ttccaataga tggattaatg
    13381 taatttttac aaatactaac ataattatta tatgtagcta aagatatatt ttcactatat
    13441 ttatttagaa aatctaatag aaattctgac actgtaattt cgcttggtac taaaaaacca
    13501 tcattatata agctttcttt tacctcattt agtcttttac ttgcttccct ttttttatca
    13561 aaagtaccca tatttttttg ttttctttta cctgtctttt catcttcaaa ttccaggtaa
    13621 acaacatagt ttttatttct ttttctaata aatgcattca tatataaccc accaatcaaa
    13681 attttataca tttattataa catatatata tcacaaaata attttgaaat agagttgcat
    13741 acattttaat acattgtata tatttattta aaaaatgtat atattatgtc aaatattaga
    13801 attttaattt gataatctgt tatacttata gaatagatat ttatctttat attaatagat
    13861 tgtgtgttta attttgaata aaaatataaa ttttttgtat taataaattt ggatgagata
    13921 ttttaaataa aacctttgac tcgaaaagtc tattaatata gtatttaatt atgtagaagt
    13981 ttgagaggag tgtaaaatca tatgactatt actaagatac caccagcaga attaaaagtc
    14041 atgaaattta tttggagttc agattttaca gtagcatcaa aagatgtcat tgaagctatg
    14101 gaaaaactat ataattggaa gcaaactaca acactaacac ttttatcaag attagtaaat
    14161 aagcaattct taagtgcaag aaagattgat agacatacac attatacagt tcttattgga
    14221 gaagaagagt atttacattt tgaaacaaaa acttttttag ataatatgca tggaagttct
    14281 attgagagtt ttatgaaatc cttgttcaaa aagggggtaa atgaagaaga attgaactct
    14341 gttgaaaaat gggttaaaga tattaaaaaa gatgaataat ttggtgtagt taattatcat
    14401 aaa
//
LOCUS       DAEQJM010000085        14166 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.086, whole genome shotgun sequence.
ACCESSION   DAEQJM010000085 DAEQJM010000000
VERSION     DAEQJM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14166
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.086"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            975..1814
                     /locus_tag="KRQ43_003204"
     CDS             975..1814
                     /locus_tag="KRQ43_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBH2743544.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            1811..2992
                     /locus_tag="KRQ43_003205"
     CDS             1811..2992
                     /locus_tag="KRQ43_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743545.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNIDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            3296..4198
                     /gene="ptb"
                     /locus_tag="KRQ43_003206"
     CDS             3296..4198
                     /gene="ptb"
                     /locus_tag="KRQ43_003206"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HBH2743546.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            4220..5299
                     /gene="buk"
                     /locus_tag="KRQ43_003207"
     CDS             4220..5299
                     /gene="buk"
                     /locus_tag="KRQ43_003207"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH2743547.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            5289..5966
                     /locus_tag="KRQ43_003208"
     CDS             5289..5966
                     /locus_tag="KRQ43_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2743548.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6009..6224
                     /locus_tag="KRQ43_003209"
     CDS             6009..6224
                     /locus_tag="KRQ43_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2743549.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            6253..7332
                     /locus_tag="KRQ43_003210"
     CDS             6253..7332
                     /locus_tag="KRQ43_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH2743550.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            7332..8084
                     /locus_tag="KRQ43_003211"
     CDS             7332..8084
                     /locus_tag="KRQ43_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH2743551.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            8085..8642
                     /locus_tag="KRQ43_003212"
     CDS             8085..8642
                     /locus_tag="KRQ43_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH2743552.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            8812..10158
                     /locus_tag="KRQ43_003213"
     CDS             8812..10158
                     /locus_tag="KRQ43_003213"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBH2743553.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILNGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            10425..12257
                     /gene="glmS"
                     /locus_tag="KRQ43_003214"
     CDS             10425..12257
                     /gene="glmS"
                     /locus_tag="KRQ43_003214"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBH2743554.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEEEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            12710..14005
                     /locus_tag="KRQ43_003215"
     CDS             12710..14005
                     /locus_tag="KRQ43_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HBH2743555.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKMQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKRAVDFSANWLNVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSITPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSNSVSLEEYRNIDNTMRNKSEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
BASE COUNT         5622 a         1552 c         2750 g         4242 t
ORIGIN      
        1 taagaaaagt ttactataaa ttatagtaaa cttttatatt gtttaaaaag acacaggaaa
       61 catgtatatt acctgtgtct ttttatttat aaactttaaa ctatgtaaaa attacagtat
      121 attctaatag agttacagta tattcattaa tattgtaaac atacggaggg taatgtataa
      181 tagtctacaa gatgtttatg aaggcatcag ttaaatataa ctaattagat aagagttata
      241 tacattatat tgtatacttt atggtattta tatattgaaa taacttatga aattatttat
      301 aaagagattt atgagcatat ttttgtctaa acaataagta taagaaatta taaaaaatta
      361 gagactatag tgaattgaca atttaatgta atatttataa gttatactaa gtaaattatt
      421 atactgtgaa atggatatat aactttaggt attgtgtatt attttcactg taggagatta
      481 tatctagtta tacataataa gttttaatga tagtttatag taagatatta aaataaattt
      541 atctaatcta gatatgaaat aagttattac tttaatataa aaatgaatct aatggaataa
      601 tattgatgat aagtaatatt tagattttgt atttgtttat agttaataag tggattatag
      661 aatttataat aattaatata tattaaacaa agatatatta agatatttta gaacataaaa
      721 ctgcattaag gcgcgagtac tattttgtat tcgcgccttg atggtttgag ttatttgagt
      781 aaaaactaac tttaataaga aatatgtatt tattaagttg atatttttaa tgtgtttaga
      841 gattatttaa caatctccaa atataaaact agaattattt acataaaagt taaatagttt
      901 gtatagagtt agatttatat agtataatac ttagtgtaaa taattaagaa gttatcaaac
      961 aggaggataa aactgtgtta gatataaatt cttttttaaa tggatttttt aatataatat
     1021 taagaatgag tatatatgat ttaattgaca tatctatagt agcgtatatt ttttacaaaa
     1081 tatttatgtt tataaaagat acaagagcag aacaagtgtt taaaggtata atatttcttt
     1141 tattagcaac tcaacttagt aacaccttta aattgcatac cgtttattgg atatctctta
     1201 aagctttaga ttatggagtt atagctgctc ttataatttt tcaaccagaa tttagagcag
     1261 gacttgaaca tataggaaga gcaaagttta atttatttgg aaagaatgta aatacttctg
     1321 aagaaactct caatagaaat atagaagaaa ttgtagaagc tttatattca ctttctagac
     1381 aaaaaatagg agctcttatc ataatggaga gagaaactag aataagtgat ataataaata
     1441 caggaactat tattgatgct gaaatttcta ggcaactatt aataaatata tttataccaa
     1501 atacaccatt acacgatgga gctgttgtaa ttagagattc taaggtaaaa gcagctgcat
     1561 gttttttgcc attgacggaa agtaaggatt taagtaaaga tttgggtact agacatagag
     1621 caggaatagg ggtaagtgag gtgtctgact gtataactct gattgtatca gaggaaacag
     1681 gtggcgtatc aattgctaaa gcaggtaagt tatatagaga tatttctaga gaaagaatga
     1741 tgaatatatt acgtagtaat ttaaaaacaa atacagaaac aagaagtttt ttcaaaggtg
     1801 gtatatttaa atgataaata gactaaaaaa taataccaaa ataaaaataa tatcattttt
     1861 aagtgcaatt gcattatgga tgtatgttat ggctgtagtt gaccctgaag aaactaaagg
     1921 gtttgaagat atacctgtat ctataagtaa tatgagtgat ttaaaggata aaaatcttgt
     1981 tatatatcca gacgaaaaat taacagcaga tgtatatata aaaggtagtt tatcaaaggt
     2041 acaaagtgtt aagaaagaag atatacatgt atatggaacc attgaagacc caatacaagg
     2101 acagaaggaa gtatatttaa aagcaaatat tcctcaaggt gttactctag aatttaagca
     2161 tgatgtttta gtagtaaatc ttgaaaaaaa cataaaagaa aaaagagata taaaggtaga
     2221 agtaagtgga aattcaaaaa gaaatataaa taaaattgaa cttagtaagg aatttgtcga
     2281 tgtatcaggt ccaagaactc tagttaaaga agtcaaaagt gtaagagcta atctagatgt
     2341 tggtaatgag acagatgatt tttctaaaaa attgcaatta ataccattaa atagtgatgg
     2401 aactaaggtt gaaggagtaa cattaagttc atcctttgtg actgcaaaga tagaactatt
     2461 gaaggaaaaa attgtcccaa taagagtaag tctaaatgat aataaagata atgatgtact
     2521 gaaaaactat aaattaagta aggaacaagt tacaataaaa ggaaagaaag aagatataga
     2581 caaaataagt tatattaaga caaaacctat tgacttagct gatttggcta atggtgaaga
     2641 aaaagaagtt agcttagaaa ttccagaggg tataactctt gaggatagct ctataacaat
     2701 taaattaaat gatacaaaac aattgagtgc agaattttta tataatgcgg gagatattga
     2761 attaagaaat atcccaacaa atatagataa tccaaatgta atttctgatg tagatataaa
     2821 agttgttgta gagtcaacgg aggatttgag taagttaaat aaaaaagata tttcattata
     2881 tattgattta tcacaaggcc ctgaggaaga tagtaaatat aaaataaaat atgaaacaac
     2941 atatcaattt aaaaaaataa atatagaacc taatattgtt gaagtggaat gaacaaatat
     3001 ttcgaatatt tagttgttac aagatgcgac aaaaaaacct ataaaattaa gtttgttaat
     3061 tttatgtttt tgttgcatct tgtttatttt agttatatta taaaataagg acaatgagat
     3121 atttgttaaa tctaaaaagc gctagatata tgaaaaaaga ctgataaata gatttaaata
     3181 aatattttga attaaatatt tcaattatct ctaggaaaac gttgctgaac gagttataat
     3241 ttaattgaga tataaaaagt tctatttcaa aaaattcaag atgaggtgga aatgcatgag
     3301 aagttttgaa gaagtaatta agtttgcaaa agaaagagga cctaaaacta tatcagtagc
     3361 atgttgccaa gataaagaag ttttaatggc agttgaaatg gctagaaaag aaaaaatagc
     3421 aaatgccatt ttagtaggag atatagaaaa gactaaagaa attgcaaaaa gcatagacat
     3481 ggatatcgaa aattatgaac tgatagatat aaaagattta gcagaagcat ctctaaaatc
     3541 tgttgaatta gtttcacaag gaaaagccga catggtaatg aaaggcttag tagacacatc
     3601 aataatacta aaagcagttt taaataaaga agtaggtctt agaactggaa atgtattaag
     3661 tcacgtagca gtatttgatg tagagggata tgatagatta tttttcgtaa ctgacgcagc
     3721 tatgaactta gctcctgata caaatactaa aaagcaaatc atagaaaatg cttgcacagt
     3781 agcacattca ttagatataa gtgaaccaaa agttgctgca atatgcgcaa aagaaaaagt
     3841 aaatccaaaa atgaaagata cagttgaagc taaagaacta gaagaaatgt atgaaagagg
     3901 agaaatcaaa ggttgtatgg ttggtggacc ttttgcaatt gataatgcag tatctttaga
     3961 agcagctaaa cataaaggta taaatcatcc tgtagcagga agagctgata tattattagc
     4021 cccagatatt gaaggtggta acatattata taaagcttta gtattcttct caaaatcaaa
     4081 aaatgcagga gttatagttg gggctaaagc accaataata ttaacttcta gagcagacag
     4141 tgaagaaact aaactaaact caatagcttt aggtgtttta atggcagcaa aggcataatt
     4201 ttaaggggga aataggcaaa tgagcaaaat atttaaaatc ttaacaataa atcctggttc
     4261 gacatcaact aaaatagctg tatttgataa tgaggattta gtatttgaaa aaactttaag
     4321 acattcttca gaagaaatag gaaaatatga gaaggtgtct gaccaatttg aatttcgtaa
     4381 acaagtaata gaagaagctc taaaagaagg tggagtaaaa acatctgaat tagatgctgt
     4441 agtaggtaga ggaggacttc ttaaacctat aaaaggtggt acttattcag taagtgctgc
     4501 tatgattgaa gatttaaaag tgggagtttt aggagaacac gcttcaaatc taggtggaat
     4561 aatagcaaaa caaataggtg aagaagtaaa tgttccttca tacatagtag accctgttgt
     4621 tgtagatgaa ttagaagatg ttgctagaat ttctggtatg cctgaaataa gtagagcaag
     4681 tgtagtacat gctttaaatc aaaaggcaat agcaagaaga tatgctagag aaataaacaa
     4741 gaaatatgaa gatataaatc ttatagttgc acacatgggt ggaggagttt ctgttggagc
     4801 tcataaaaat ggtaaaatag tagatgttgc aaacgcatta gatggagaag gacctttctc
     4861 tccagaaaga agtggtggac taccagtagg tgcattagta aaaatgtgct ttagtggaaa
     4921 atatactcaa gatgaaatta aaaagaaaat aaaaggtaat ggcggattag ttgcatactt
     4981 aaacactaat gatgctagag aagttgaaga aagaattgaa gctggcgatg aaaaagctaa
     5041 attagtatat gaagctatgg catatcaaat ctctaaagaa ataggagcta gtgctgcagt
     5101 tcttaaggga gatgtaaaag caatattatt aactggtgga atcgcatatt caaaaatgtt
     5161 tacagaaatg attgcagata gagttaaatt tatagcagat gtaaaagttt atccaggtga
     5221 agatgaaatg attgcattag ctcaaggtgg acttagagtt ttaactggtg aagaagaggc
     5281 tcaagtttat gataactaat gataaaagaa taagaatcat aactggtcac tatggaagtg
     5341 gtaaaagtga atttgcgatg aactatgttg ttaagttaag agatatggtt tctggcaaag
     5401 ttgctatagc cgatttagat gtggtaaatg tatactttag aactagagaa aagaaagagt
     5461 taatgaaatc cttaggtata caaccaatag atagctcaat taatgctcca acattagatt
     5521 taccagcagt atcagcagag gtaatgtctc ctatggtaga ccattcatac aattctgtta
     5581 tagatttagg tggagataat gtaggtgcta gggttatagg aagatttagt catttgttaa
     5641 aagaaggcga ttatgatatg ctttttgtaa taaatgcaaa tagggagaaa actcaaactt
     5701 ctgaagaagt tatccaatat ataaaagaaa tagaaaaatc ttctaaatta aaggtaacag
     5761 gtctaattaa taatactcat cttattaggt ttactactat tgatgatgtt ttaagaggtc
     5821 agaaagttgc aaaagaagtt tctgaaaaat gtaatatacc gataagatat gttgcatgtt
     5881 tagaaaatct tgttgaacag ttaccaaaag atttagaagg agaaattttt cctataaaat
     5941 tatatatgag agaagactgg atgtagtttg agctcaaata tatagaaagt ttaaggaggc
     6001 ttaggtaaat ggctaaagga aaagtatctt ttaatcaaga acgttgtaaa ggttgtggat
     6061 tgtgtgttga agcatgtcca gtaaaaatca tacaattaga ctcaaatgta ataaacaaaa
     6121 aagggtataa cccagcaact gtttttgaaa tggaaaaatg cataggatgt gcaagttgtg
     6181 caactatgtg tccagatgta gttataacag tagaaagaga ttaatttaat taatatttaa
     6241 gggggaattt taatggctaa gatacttatg aaaggtaacg aagcatttgg aaaagcagct
     6301 atagaagctg gttgcaaata tttcttcggt tacccaataa ctccacaaag tgaattacca
     6361 gaatatttat caagagagtt acctaaaata ggtggagcgt tcgttcaagc tgaatcagaa
     6421 gtttctgcga taaacatggt ttatggtgga gcaggtgcag gagcaagagt tatgacttct
     6481 tcatcttcac caggagttgc tttaaagcaa gaaggtataa catatgcagt aggagcagaa
     6541 gttccttgtg ttgtacttaa tgtaatgaga ggtggtccag gacttggaag tatacaacct
     6601 tcacaagctg actactttat gtctacaaga ggtggaggaa atggagacta cagaactcca
     6661 gtattcgcac cagctacagt tcaagaagct gttgatatga taatggaagc ttttgacgtt
     6721 gcagattatt acagatcacc agttatggta gttgcagatg gtatgatagg tcaaatgatg
     6781 gagccagttg aatttagagc tcctgagaag aaaagagaat tgcctcctaa agattgggca
     6841 actgttggaa ctaaaggaaa aagaaaacct aatgtaataa actctctata cttagaacca
     6901 gaagtactag aagaccattg ttggcattta caagaaaaat ttgatgcaat ggaaaagaat
     6961 gaagtacaat acgaaatgta caaaacagaa gatgctgaat ttgtatttgc agcttatgga
     7021 actacttcaa gagtagtaaa aagcgcaatt gatatattaa gagaagaagg aataaaagca
     7081 ggtcttataa gacctaaagt attatggcca ttcccattcg aagcattcaa ccaaattcct
     7141 aatgctagaa acatattgac tgttgaaatg agtatgggac aaatggtgga agatgttaaa
     7201 atggcagtag aaggtaaatt accagtttac ttccatggaa gaccaggagg aatgactcca
     7261 acaccagcag aaatagttga aaaagctaaa aaaattattg ccggagaatt ggttgcagga
     7321 ggtgctagat aatggctgtt gtatttaaga aaactgaagg attacaagat actcaaactc
     7381 actactgtcc aggatgtaca catggtataa tccatagatt agttggtgaa gtattagaag
     7441 aactaggagt attaggtgat gctgtaggtg ttgttccagt tggatgttca gttttaggat
     7501 ataaatattt taactgtgac actcaagaag ctgctcatgg tagagcgcca gctgctgcta
     7561 caggaataaa aagagttcat cctgaaaata cagtattcac ttatcaaggt gatggagact
     7621 tagcttcaat tggtactgct gaaatagttc atgcagctgc tagaggagaa aaaataacta
     7681 ctatatttgt aaacaataca acttatggta tgactggtgg acaaatggct ccaactacat
     7741 tagttggaca aagagctact actgctcaat caggaagaaa tgctgaaact caaggttatc
     7801 caataagagt aagtgaaatg ttagctacat taacaggagc tgtatttgta gaaagagtag
     7861 cagttgatac tccagctcat gttagacaag ctaaaaaagc tataaagaaa gcattccaag
     7921 ttcaacaagc aggattagga tttggaatag tagaagtatt atctacttgt cctacaaact
     7981 ggggactagc tccaaacgat gctttacaat ggttaagaga caacatgata ccatactatc
     8041 cattaggaaa tttcaaaaat gttgaagttg aggaggtgaa gtaaatgtct acagctagag
     8101 taatatgtgc aggcttcgga ggccaaggtg ttatgtctat gggacaatta cttacttatg
     8161 caggaatgct agaaggaaaa gaagtttctt ggttaccatc ttatggacca gaaatgcgtg
     8221 gaggtacagc aaactgtgca gtaactgtat ctaatgagcc agttggttct ccacttataa
     8281 cagatgatgc aactgcagct atattattaa atataccagc atttgaaaaa ttcaaagatg
     8341 atgttattcc tggtggaaaa ataatagtaa atagttcttt aataaaagaa aaagttgata
     8401 gaacagatgt agatgtttat tatataccag caaatgaatt agcagctgaa ttaggaaatg
     8461 ataaagttgc taatatgata atgttaggcg cttacttaaa agtatctgat actgtagata
     8521 tagaatctgt actagaagca ttcaaaaaag ttttcggacc tagaaaagaa aaattcgttc
     8581 cattaaacag agaagcttta caaaaaggta tggatgctac atgttctaaa gcaactaact
     8641 aataaagaaa aagatgtcaa aaaaaagaca atagaattat ttctattgtc ttttttgctg
     8701 ataagtatta aaatgttttt atgactgaaa ttaagcctat aatgatattt tatgaactat
     8761 aaaaatataa tacaaattac aagcttttca attatgaaag gagaatcttt agtgagaaag
     8821 tattttggaa cagatggagt tagaggagta gcaaatacag aactaacatg tgatttagca
     8881 tataaacttg gtagagctgg tggatttgtc ttagctcaag gagaccacag agtaaaagta
     8941 gtagtaggta aggatactag aatatcaggt gatatgttgg aagcatcttt aatagcagga
     9001 cttatgtctg ttggatgtga tgttattact gttggaataa taccaacacc tgcagtggca
     9061 tatttaacta gaaaatatgg tgctgattgt ggtgtggtta tatctgcatc tcacaatcct
     9121 gttgaatata atggaatcaa attctttaat aagaatggat ataaattaga tgatgaaatt
     9181 gaattgaaaa tagaagaata tatagacgat atagacaaaa ttgattgtct tccaattggt
     9241 gaaaatgtag gaagaaaatt acatgaacat tgtgcacaaa gagactatgt agactaccta
     9301 aaatcaataa taagcactga ctttaaggga ttaaaagtag ttttggactg tgctaatggt
     9361 gcgtcatata aagtggcacc aatagtgttt gatgaactag gagcaagtgt aatttcaata
     9421 aatagttcac cagatggaaa taatataaac tataaatgtg gctctacaca tccagaacaa
     9481 cttcaaaggg ctgttttgga acataatgct gacttaggtc ttgcatatga tggagatgct
     9541 gatagattaa ttgcagtaaa tgaaaagggt caaattgttg atggagacca tataatgata
     9601 ttgagtgcct taaatttaaa gaaaaataat aaattggcgc aagatacttt ggtagttaca
     9661 gttatgagta atatagggtt gacaatagct gctaaggaaa atggaataaa tttatctact
     9721 acagcagttg gagacagata tgttttagaa gatatggtta aaaatggata taatcttggt
     9781 ggagagcaat ctggacatat gatattttta gattacaaca ctactggaga tggagtgctt
     9841 agttctctaa tacttgcaaa tataatcttg caagaaaaga aacctttatc agaaattgca
     9901 tcaataatga gccaataccc acaagtatta gtaaatgcaa caataaaaaa tgaaaataag
     9961 aacaaatata tggaatatcc agaaataaaa actgagatag aaagaataga atctatttta
    10021 aacggaaatg gtagagtttt gataagacca tcaggaactg agccattagt tagagttatg
    10081 ttagagggta aagaggaagg tcaaataaaa gaattagcaa caaacttagc taatcttata
    10141 caagaaaaat tatcgtaatt taaagggtat tctcagatac aaatactgag gacacctttc
    10201 taagcgccag aacttagtta tagacataat tattgagtaa tataggaact aagttgacga
    10261 ggtcagagtt aatcgaattg tcggcggatg ctctgcggtg tgtttaccat cgaaagactt
    10321 ctttaaataa taggagcaat cctatggaca aagggaagcc aaagtaaact tatatgacct
    10381 aactcttaaa atatataaat aatattttta ggaggacaca aataatgtgt ggaatagttg
    10441 gatatttagg aagtagaaag gcagcagaag ttatagtaga agggctttct aagctagagt
    10501 acagaggtta tgactcagca ggagtagcag ttaatagttc taatgaagaa gaacttaata
    10561 ttagaaagtt taaaggtaga ctttctgtac ttgcagaaga cttagaaaag aatcctattg
    10621 atggaaattt aggtataggg catacgagat gggcaactca tggagaacca tctgatgtaa
    10681 actcacatcc tcattttaat caagccaaaa caatagcagt tgttcataat gggataatag
    10741 aaaactatat ggaaataaaa gaagaattaa tttctgaagg tgttaagttt gaatctcaaa
    10801 cagatacaga ggtaatagca catttagtag ataaatacta tgagggtaat ttattagatg
    10861 ctgtatacaa aactatatca aaattaagag gagcttatgc attaggtgtt atatgtaaag
    10921 aacatggaaa tgaattagtt gcagtaagaa aagatagtcc tcttgtagtt ggtgttggtg
    10981 aaggtgaaaa ctttatagca tcagatatac ctgcattatt aaaatatact agagatgttt
    11041 atttcttaga aaatggagaa gtagttcatc taaaagacga aaatgtaaca gtttatgact
    11101 ctaatagaaa tcttgttgaa aaagaagtat ttcatgtaac ttgggatgta gaagctgcgt
    11161 ctaaaggtgg atatgactac tttatgtcaa aagaaattca tgagcaacca acaggagtta
    11221 gagaaacttt agaaagaaga cttgatgata atggaaatat aattctagac agtataaata
    11281 tttctaaaga agacttagaa aaaataaata aagtttatat agtggcttgt ggaacagcat
    11341 ataatgctgg attacttggt aagtatgcca tagaaaaatt tgtaaatata ccagtaataa
    11401 ctgatatagc atcagaattt agatatagcg acccatttgt agatgaaaat tcattagtaa
    11461 tattagttag ccaatctggt gagacagcag atactctagc agtattaaga gattcaaagg
    11521 ctaaaggagc aagaatactt tcaataacta acgttgtagg ttcatctata gcaagagaat
    11581 cagatgatgt attctatact tgggcaggac ctgaagtagc agttgcatca actaaggcat
    11641 atactactca aataacttct ttatacatga tagctttaga ctttgctatc aaaaaaggaa
    11701 caataactag agaattttat gatagtatga tttctaagat gaaagaaata ccatcaaaaa
    11761 tacaagaaat attagacaat gaagaatata taaaagaagt tgctaaaaca gttgttagtt
    11821 ctgaacatgc attctattta ggaagaggta tagactatag cttagcaatg gaaggttcat
    11881 tgaaattaaa agagatttca tatatacatg cagaagcttt tgcagcagga gagctaaagc
    11941 atggaacaat agctttaata gaaaaaggaa ctcctgtaat tgccatagct actcaagaaa
    12001 agttatttga aaaaatggtt tctaatatgg aagaagtaag agcaagagga gcttatgtag
    12061 tagcaatagc tcaaagccat aataaggatg ttgagaaagc tgctgataaa ataatctata
    12121 taccaaattc agatgatatt ttatcaccaa tattagcagt tgtaccaatg caattacttg
    12181 cgtatcatgt ctctgtacta agaggatgcg atgtagataa gccaagaaat ctagctaaat
    12241 cagtaacagt tgaataaaaa cagattaaaa attaaataga taatatttat tgaaaaaaac
    12301 tcatcctgtt atttgtattt tataggatga gttttttaga taaatattaa atttgttttg
    12361 tttttgctat aataaatttt ataaaaagat tgatattaaa tcatctgtaa aatgataaat
    12421 atatagacca taccaggtat agggaacgat aaatatagtt catataaaat atagtgagta
    12481 cttaataaac atatagtcaa tatcagacat aaaaaaataa tagcttatga gaaaaattaa
    12541 aatacaaggt attagtaacc ttgtgataag ataaagtgag tagtttaaaa taagaatata
    12601 aggaactatt tataaaagaa tataatgaag ctaatagagt ataagaaaat tactttattt
    12661 tagtaaaata atttcaaata aaaatttttt taaattggga gtataaatta tgacaaatga
    12721 ttttaaaaaa gaaaagaaag aagattattt tgttaatctt aaggcaatat ctactgaagt
    12781 tttacaagaa aaaatgcaag ataacgcttg ggttatagtt gatactcgct taaatgatgc
    12841 ttataatggc tggaagttag atggagtaaa aagaggtggg catataaaaa gagcagtaga
    12901 tttttctgct aattggttaa atgtatactc agatagaaaa gatgaagtgc tagaacaagc
    12961 attgaaaact aaaagaattg atttagataa aaatatagta ttgtatgatg caaatggaaa
    13021 agatgctttg gttgtagcag attatttatc taaaaaagga tataaatatc tatataaata
    13081 tgatattaaa caatgggcag acgatgaaaa tcttccaatg gaaagatata aaaattatca
    13141 aatgatagtt cctgctttta taataaaaga tatattagat ggaaaaattc ctgagacatt
    13201 tgaagattca aagaatataa aaatgattga agcgagttgg ggagaagaat cgtatacaaa
    13261 agggcatata cctacaagtg ttcatgtaaa tactgatatt atagaacctc ctccaacatg
    13321 gatgcttgat aatgatgata acttaactaa gtttgcttta gactatggac taacaaagga
    13381 tgatactgta atagtttcaa gtattacacc tatggcatct tatagactag ctgttatatt
    13441 gagatatata ggagtaaaag atgtaagagt tttgaatggt ggaacaaact catggttatc
    13501 agcaggatat gaattagaat ttattagtaa tccaaaacat tcatgtacta attttggagc
    13561 agatatacca gttaactcac aattagttgt tactacatct gaattaagac aaaaactaaa
    13621 agaaaaaaat aagtttatac tagtagataa tcgtacttgg gatgaacata taggaaaagt
    13681 atctggatat acatattatg ataaaaaagg gcgtatacca ggagctttat atggacattc
    13741 aggtagtaat agtgtttcac tagaagaata tcgtaatatt gataatacaa tgagaaataa
    13801 atctgagatt ttagaaatgt gggacaagga aaatatagat gtgaataaac agcttatatt
    13861 tatgtgtgga agtggatggc gtgctgctga agtattaaca tatgcaaatg tcataggagt
    13921 ggaaaatacc tccctttata gtgatggatg gatgggctgg agtcttgata attcaaattt
    13981 aattgaagtg ggagaacaca aataaagttt ttgaaagtac aatagagttg tttaaaacaa
    14041 aggtgttttt gatttattag gaagagtgtg taaattgtgt attgggaagt gtacttaggt
    14101 atgttcattt ggagctatgg aaattgataa aaaagtatta tctgtttatt ttgctggtaa
    14161 aatatg
//
LOCUS       DAEQJM010000086        14155 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.087, whole genome shotgun sequence.
ACCESSION   DAEQJM010000086 DAEQJM010000000
VERSION     DAEQJM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14155
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.087"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            32..838
                     /locus_tag="KRQ43_003216"
     CDS             32..838
                     /locus_tag="KRQ43_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH2743556.1"
                     /translation="MGMILSTLGINLYLAPAKLLSGGVAGICVILYKLFGINQGISSF
                     LMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLTQDIAKYFPIDDTMLQCIYGGAL
                     TGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNTFLFINFFVVCAGAFLFGAKLVM
                     YTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEISKVIMNKMGRGVTFLEAEGAYT
                     QNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNNVEEVKGGGFKDKFL"
     gene            965..1237
                     /locus_tag="KRQ43_003217"
     CDS             965..1237
                     /locus_tag="KRQ43_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743557.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(1400..1972)
                     /locus_tag="KRQ43_003218"
     CDS             complement(1400..1972)
                     /locus_tag="KRQ43_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2743558.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            2156..2998
                     /locus_tag="KRQ43_003219"
     CDS             2156..2998
                     /locus_tag="KRQ43_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH2743559.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            complement(3101..4177)
                     /locus_tag="KRQ43_003220"
     CDS             complement(3101..4177)
                     /locus_tag="KRQ43_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH2743560.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            4674..6077
                     /locus_tag="KRQ43_003221"
     CDS             4674..6077
                     /locus_tag="KRQ43_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH2743561.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFMLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     TSLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    6168..6408
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6451..7149
                     /locus_tag="KRQ43_003222"
     CDS             6451..7149
                     /locus_tag="KRQ43_003222"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBH2743562.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILKGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            7172..8173
                     /gene="trpS"
                     /locus_tag="KRQ43_003223"
     CDS             7172..8173
                     /gene="trpS"
                     /locus_tag="KRQ43_003223"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBH2743563.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(8825..11455)
                     /gene="cdtB"
                     /locus_tag="KRQ43_003224"
     CDS             complement(8825..11455)
                     /gene="cdtB"
                     /locus_tag="KRQ43_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094607992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin binding subunit
                     CdtB"
                     /protein_id="HBH2743564.1"
                     /translation="MKIQMRNKKVLSFLTLTAIVSQALVYPVYAQTSTSNHSNKKKEI
                     VNEDILPNNGLMGYYFTDEHFKDLKLMAPIKDGNLKFEEKKVDKLLDKDKSDVKSIRW
                     TGRIIPSKDGEYTLSTDRDDVLMQVNTESTISNTLKVNMKKGKEYKVRIELQDKNLGS
                     IDNLSSPNLYWELDGMKKIIPEENLFLRDYSNIEKDDPFIPNNNFFDPKLMSDWEDED
                     LDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEK
                     ASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTES
                     NTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINAN
                     VRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALN
                     TMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYIS
                     QIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYF
                     NDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDD
                     YNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSN
                     SIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITE
                     LNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEAL
                     DYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYK
                     KLRIYAITPDDRELLVLSVD"
     gene            complement(11508..12899)
                     /gene="cdtA"
                     /locus_tag="KRQ43_003225"
     CDS             complement(11508..12899)
                     /gene="cdtA"
                     /locus_tag="KRQ43_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin enzymatic subunit
                     CdtA"
                     /protein_id="HBH2743565.1"
                     /translation="MKKFRKHKRISNCISILLILYLTLGGLLPNNIYAQDLQSYSEKV
                     CNTTYKAPIERPEDFLKDKEKAKEWERKEAERIEQKLERSEKEALESYKKDSVEISKY
                     SQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTEN
                     QNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLP
                     YTNTNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKA
                     NYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKR
                     EPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIG
                     SVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKINKIDSYKDG
                     TITKLIVDATLIP"
     gene            complement(13289..14035)
                     /gene="cdtR"
                     /locus_tag="KRQ43_003226"
     CDS             complement(13289..14035)
                     /gene="cdtR"
                     /locus_tag="KRQ43_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HBH2743566.1"
                     /translation="MDILIFDNDVCFGIKLKEKINNILIKEGFDNDVIRLYYNANLLL
                     KELTEKNKVKIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYVKEKNYRSNFFTIYSDSSLWKISF
                     DEVIYFETSAIPHKIKLVTTSRIFEFYKSLRSLSDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT         4970 a         1843 c         2076 g         5266 t
ORIGIN      
        1 taacatattt ttacaatatg gtctgattat attgggtatg attctatcaa ccttaggaat
       61 aaatttatat ctagcaccag ccaagttatt aagtggagga gtagctggaa tttgtgttat
      121 attatacaaa ttatttggta taaatcaggg aatatcaagt ttcttgatga acataccaat
      181 atttattata gctagaaagt attttgataa taaatttttg ctaataagtt ttgtcaatat
      241 gttactgttt tctctagcac tggggctaac acaagatatt gctaaatatt tcccaataga
      301 tgatactatg ctacagtgta tttatggtgg tgcattaact ggtataggta tggggttaac
      361 ttttaaagca agagctactg ctggaggact tgatataata gcagccataa tgaaaagaaa
      421 gtatgatata cctatgaaaa atacattttt atttattaat ttttttgtag tatgtgcagg
      481 agctttctta tttggagcta aattggtgat gtacacttta attacaatgt atataatttc
      541 ttttactatg gatataggaa aagattgctt tgatagaaaa aaatctatac ttttaatatc
      601 aaataaatat gatgaaatat ccaaagtgat aatgaataaa atgggtagag gagtcacttt
      661 tttggaggca gaaggtgcat atacacaaaa taagaaaaag atgatttatt gcataatatc
      721 tgcaaatgaa ataggtaaat ttaaagattt aatttatgat atggatagtg aagcttttat
      781 ttctgtcaat aacgttgaag aagtaaaagg tggaggtttt aaggataaat ttctttaaga
      841 ttatatatgt taattatata tgttaaaaaa tgccatatgt attgagatta tacctagtta
      901 gatgtatact gtagttaatg gggtacatga agtattcaat aatatactag gaggtataag
      961 aattatgtta agagagagat ttgtagtaag aaatcatcat aatccacata caagtgggtg
     1021 ttgtgggact ggaggagaag gatgctgtgg aggagataac catgaacatt cacatcaaca
     1081 ttctcacagt catgggcatg aacatgagca tgtaaatggt gtaggtcacg accataatca
     1141 tgatgatggt ttttcaggta ctcatgagca tagccatgag catacacata cacatggtca
     1201 tgaacattca gatgggcata cacatgaaca taaataaaaa cattttaaat ttataagaga
     1261 tttttatttt gtgattccat gaaggtttaa ataaaaattg aatgttttaa gtaaaaatta
     1321 ttgagaataa ataagaaagt gaactgttaa agtagataac ttaaatagtt cacttttatt
     1381 aattatctaa gtattaagtt taaatccaat gattaactaa aaaagaagct atattttcat
     1441 aaggtatttt ttctgttttt aataaacttt ggacaactaa accatcaact attgacatga
     1501 gtaaaaaaga aaatgattca gcatcctgtt cattttcgct actattatat ttttctagtg
     1561 attcaacaat ttcagattta agagtagttc tccattcaat atattttaat cttattcttt
     1621 cctttaaatc attatttgaa gtaattgcct cacaaataag atacatatgt accctaccac
     1681 gactttctat agtagatatt ttctctaaga ttaagttaac catttctatt tgagaatttt
     1741 ttgatttgac attttttaca cagtttagta tagcactagt tataacttct aaatgagtat
     1801 ccgcaatatc atatataata tcatctttag atgcgtagtg ataatacaaa gtacctttac
     1861 ttatatttac atcttttgca atatcagcaa ggctagtatt ttgaactcca tttttggcta
     1921 ttaaattggt tgcagatgat aaaatagcct gtttcatatt atttgttttc ataaaaccta
     1981 cctttccatg tatatttata acaaattaat aacattataa gcttatgaat atttattgtc
     2041 aataaagcga gaatctatat ctattgactt tttttcattc aatatataaa ataataatta
     2101 aatcggtcgt acgaccgact gaataaataa aataatatct tatagtgagg ttaatatgga
     2161 taaaataaaa ttgatagtgg acagtgcatg tgacttacct gatgatataa tagaaaaata
     2221 caacatagaa gttgttggtt taaatgtatc ttttggagaa gaaagttata tatctggaaa
     2281 ggaaatagat aatgaaactt tctatagaaa aatgagtgag agtaaagtac taccaaaaac
     2341 atcatgtcct tctcctgata aatttttaga agcataccat tgtcaggaag aaagtgtatt
     2401 ggtgattaat ataagttcag gattatctgg gacttataat agtgcacttt tagcaaaaga
     2461 tatgtttgaa aaggaaggaa ataacaaaaa agttgaggtt atagattcac ttagtgggtc
     2521 aattggaata ggacaattag tgttaaaagc agcaatatta ataaaagaag gaaaagaaat
     2581 tgaagagatt gtttcaataa taaataaata taaagataat cctccatttt ttggaacact
     2641 tgaaacttta gaaaatgcta ttaagggtgg tagaataaat ccaatagcag gaaaaattat
     2701 aaataccttg aattttaagg cgataataca agttgcagat ggcgttgtaa ctcctataga
     2761 taaggcaaga ggtgaaggaa acagtttgaa aaagctgatt actttagtag agtcaaaaat
     2821 taaagataaa gaagaaaagg ttttatttat aggacatgct aattgcccag aaaaggctca
     2881 aaaggtaagg gaagttatgg aaaaggatgt aaaatacaaa gatgttgtaa tctgtgaaat
     2941 tggttcagtg atggggacat atacttcaaa gggtgcaatc ttaataactg caatataaat
     3001 aatggattga aataaatcat agattgagaa attaaagcca tataaaaatg tttaaaacat
     3061 ttttatatgg ctttttaatt ttatcaaatt gattttagaa ttaaccaact acacatattt
     3121 ctttgtcatg tttgtttaat atctcacaac catcttcagt aacaagtact aaatcttcta
     3181 ttctaactcc gaactcacct ggtaaatata tacctggctc tatagagaat atcattcctg
     3241 gttgtacagt atctgtattt atagaagata catctccttt atcatgaact tcaagtccta
     3301 tagagtgacc agttctatga gtgaagtact gtccatatcc cttttcagtt atgtagtcac
     3361 gagcagcagc atctatatca cagaatctaa cacctggttt tacaatagct tcagctctct
     3421 tattagcttc aagaactatt tcaaatattt ctctaccttt ttcaggtatt tctttataga
     3481 atacagttct tgtcatatca gcacaatagt tatcttttat acaacctata tctaatatta
     3541 ttgcatctcc tggtttcaca agtgcatttc caggttcacc atgtggatta gctccattag
     3601 gtccaaaacc tataataggg tcaaatgaaa atccatcagt acctaggtct tcatatattt
     3661 tagataattt accaacaagt tgtttctctg taagttcacc agaaacagta gctttaagtt
     3721 gttccatagc cttgtcattt aattttgaag ctattctcat taactctttt tcttcttcat
     3781 ctttacacat tcttaaagta tctattatat aagatgaatt tacaaactta cttcctccac
     3841 ctaattctat taagtttaat aagaatctag ctggccagtt tttatcaaca cccatagtag
     3901 catttttgtc tatatgttca gttattattt ctactggatt ttgagtatca ttaaaccaaa
     3961 ccatttcaac acctaaatct tctgaaactg ggaataattc atttataaat aatttattat
     4021 tgccatttaa atttaagtat aatgctaata atctttcacc tggatggatt agtactcctg
     4081 taagataaaa tatagaagta gggtcactta ctaacatttg agaaatatca tcttttttca
     4141 tttgttcaag tacagcattt aatctttgag ctttcataat aatttcctcc taatcaaaat
     4201 tcaatacaaa tcaattttag cattattaaa caaaaaagag tatacttttc ttctagaaat
     4261 ataaaaaaag tttgttatat attttttata ttaagtttaa tctctacttt tgcattaaat
     4321 acggaagtaa aatgactttt tattgtgaaa attctataaa agtaataaat taagtctata
     4381 aagttatgta ttttatcttt ttatatacta atgaaaaata ataaataaaa ttttataata
     4441 aaataatatt gaaacaattt taaaaattta gtatcattag aattaaagtg gtaaaacttt
     4501 taaatttatc atttttaata agatttgatt tcaaagtatt taaggtttat tattaaaact
     4561 gtttttgaat atgcaaatat tttgaaaaat atcagtttaa taataatgaa tctattttat
     4621 taattttgaa attaaattta aaataattaa tagagagggg aaatgaaatt aggatggaaa
     4681 agaaaaaaat aggcctatgg agtttggtat ttatgaatgt atcagcttta tatggtataa
     4741 gatggatagc taagtctaca gcatcaagct ttggtttagg attaggtgca atacctatgt
     4801 ggttattatt ctcatttata tactttgtac caggagcttt aatttgcgct gaattagctt
     4861 ctacatatca aaagggtgat ggaggtcttt acgattgggt taaggaagcc tttggagaaa
     4921 agtatggatt tttagtttct tggttaaact ggacagctaa aatattttgg tattcttcat
     4981 ttttaacttt cttagcagta aatgtttctt atacaatagg aaatccagct cttgctgata
     5041 ataagatgtt tgtacttata ttatctttaa taatattctg ggcattatct cttatagcaa
     5101 ctaaaggaat aagttttaca aaaatattta ctaatacagg tgcattaggt tcaacaatac
     5161 caagtgctat acttataata ttttcatttg tagcagtatt tatgttgaaa aaacatgata
     5221 tagcttctac atatacaata gcttcaatga ctccaaaact taatatggat gcatttgttg
     5281 ctatatcagc tataatgttt ggtttagcag gagcagagac tgctgctaac ttcataacag
     5341 aaatagataa gcctgaaaag aacttcccta aggcaatatt aatatcagct ggaatagtag
     5401 cttcattata tgtattaggt tcaattgcaa taacaatgat aataccacca gaccaaatta
     5461 ctgcttctaa aggtgtatta gatgcacttt ctgctgtttg tacgtcttta ggaattggtt
     5521 cttggttggt tcaattaata gcttttggta tagctttctc agtattagga gcaatagttc
     5581 tttatatagc atcaccaata aaaatgttat ttggtagtgt taaaaaagga atatttccag
     5641 atagtttggt agaggtaaat gaacacaaga taccttctaa agcagttata cttcaagcaa
     5701 taatagttac tataatacta ttggtgacta cattaatgcc ttctgttgat gctatataca
     5761 atgttcttgt aactatgaca gcattaactg cattattccc atatgtatta ttatatgctt
     5821 cttatattaa actaagaaaa gagagaccag atgaaattag accttatact atggcaaaat
     5881 caacaagtac ttgcctaggt ttagcaaaaa tggttttagt tgtaactgta gttggtatat
     5941 tattatctgc agcaccagtt atgccgacat ttgctgaaaa tgttatatat gagatagaga
     6001 tgattggtgg aggtcttcta gttatattat ctggtctatg gttatggaat agatatgaaa
     6061 agaaaacagc taaataaaat gtattttaaa aatttctttt ggatattata atatatagtt
     6121 gacaatttat agtgtaagga atattataaa ataaagaaat taataaatta aatcctgaga
     6181 taagaaatag taaataaata tatttttgca cagagaatta aggatgctga gaacttaata
     6241 aaaagtattt attgaatggg tctttgagga gtaaaatgaa atgtaattta agattacaga
     6301 gtatttgata tcgtgtatgc acgttatagc atatattaag atatatatat tcagttttga
     6361 gtgtatataa atttaggtgg taccacggaa aatatatccg tcctattgat ttaggacgga
     6421 ttttttaata tagaaaattt aggaggaaaa atgaacgtaa taggaattat aggtgcaatg
     6481 gatgaagaag ttagtatttt agttgattta atggatatta gagagactat aaaaaaagct
     6541 agcttagaat tttataaggg aattttgaaa ggtaagaatg tagtgttagt aaagtgtggt
     6601 ataggtaagg ttaactctgc tctttgtgcc cagatactaa taagcgaatt taaggttgat
     6661 gctattgtta atacaggtgt tgcaggagct ttaaatgaaa aacttgatgt taatgatata
     6721 gtaatatcaa ctgatgctat acagtatgat gtagatacta cagcatttgg agaccctaag
     6781 ggagttatac caagaatgaa gacttctgta tttaaagcag atgaaagact tatagatgct
     6841 gcttacaaat cttctgtgga agaagtaaag actcataaag tattaaaagg aagagtagtt
     6901 acaggagata aatttataaa ttctaaagaa ttaaaagaag aattagtaaa tgattttggt
     6961 ggatattgtg gagaaatgga aggtggagct atagctcatg tatgctattt aaataatact
     7021 ccattcgtaa taataagagc aatgtctgat aaggcagatg gaagtgctga tgttacttat
     7081 gatgtatttg tacatgatgc tgccaataac tctaaagaca tagttttaaa tatgttaaaa
     7141 tcaatataaa tatataagga ggtacaaaaa aatgagtgaa aaaaaagtta tatttagtgg
     7201 agcacagcca tcaggcaaaa tgactttagg aaattattta ggagctataa aaaactggac
     7261 tgaacttcaa gataattatg attgctatta tagtatagtt gatttacatg caataacagt
     7321 acctcaggac cctaaagttt taagagcgaa tgctatagaa ttacttgctc aatatatagc
     7381 ttgtggatta gacccagaaa aaaatactat atttatacaa tcacatgtca aagagcatgt
     7441 tgaacttatg tgggtattga atactatgac ttatatgggt gaattaagta gaatgactca
     7501 attcaaagat aaatcacaaa agagtgaagc aaatctaaat gcaggtttat tcacatatcc
     7561 agttcttatg gccgctgaca tattgttgta tcaaactgac ctagttccag ttggagatga
     7621 ccaaaaacaa catttagaat tagctcgtga tttagcaaat aggtttaata atagattttc
     7681 acctactttt gtagttccag aaggatacta cccaaaaggt ggagcaagag tgatgagttt
     7741 gcaagagcca actaaaaaaa tgagtaaatc cgattcaaat gaaaatgcat ttatactatt
     7801 agcagatgat tcagattcta taaagagaaa gataaaaaga agtgttactg attctttagg
     7861 tgttgtaaaa tacaatgatg aacaaccagg tattaaaaat ctaattgata tatattctaa
     7921 tttaagtaaa aagagtgtag aagagattgt aaacatgtat gaaggaaagg gttatggcat
     7981 atttaaagaa gatgtggctg aagtagtatc agaagcttta agacctataa gagaaaaata
     8041 tgttgacctt cttaataata aagattattt agaaaaaata tatagtatgg gagcagaaaa
     8101 agccgaaaaa caagctagaa aaactcttag aaaagtttat aaaaaagttg gatttataga
     8161 gagaagatac taattattag ctatctttac ttgataaata aattttaaag ttattaaaaa
     8221 ggtatatgat atgaaagaga gagtctcaaa gtgaactttt gttcatgaga cactcttttt
     8281 tgtatgaaat aaaatatatt ttaatcactt caacaatgaa aaagaggatt atctctattt
     8341 tgagacagca tcttttgata ataaaaaaag atgagctttt gctcatctca aaggggttag
     8401 attattctta ctttggggaa agtagaataa aggtaaaagt taactgatgt caactttgtc
     8461 ttttttgcat atcactactg agcataaaaa aatcagaaaa ccatagcctt ctgaaacaac
     8521 ttctaacata cattgtattt tatacccaat atgtaattta tgagttaatt ttaactctta
     8581 taatggaaat tgtcaataat atatcaaaaa aatatttttt aaatttatat aattaaatga
     8641 atttatgttt atatataggt gatatgatac agataattat ctttataata caatatagtt
     8701 ctaaaaaaga atatgttaga agaagagaat atttaaataa aaaatacctt ataaagttaa
     8761 ttttttagta ctttataagg taaatatata ttgtattgtg gggacaaatt taaatcattt
     8821 gatactaatc aacactaaga actaataact ctctatcgtc tggagtaatt gcatatattc
     8881 ttaatttctt gtatgtcata atattttctc cacctgtaaa ataactccta agattaacat
     8941 aattagtttt aggctgattt ggatctccta aataattacg catttcttta tctttagttc
     9001 caatatcttt aaatccagaa tattgtaaag tagcttcaac tctatatttt tggatataat
     9061 cgagagcttc tttattagtt tgtgttggtg caaaatacat accatttata taagtatttc
     9121 ctgtacttgg attaaaattt aaatctgcaa aatatatttt atgtgcatcc attatttctt
     9181 ggtcagttgg aattttaact tctggttcat caagtatttc aggagtacta tttagctctg
     9241 taatagataa gttatctaag tatgttgtac cactaccaat taatgttatc tctatattag
     9301 aagaatcttt ttcagtagtt tcaaattcat aactaaattt tgtatatcct tgttctggta
     9361 ccaaataatc cgttttctct tcttttgctt ttatctttac aattattgaa ttagatgtta
     9421 aaggatcctt tgaatatcca ctaaaaacat aacgtttata aggttttagc tcagacatag
     9481 ggattttaat cttcgtctca ccatttaatt tatttgctga gccttgtaaa ccatcttgat
     9541 tcgtagtatt gacattactc catgtactag ggtaattatt ataatcatca aaattagtaa
     9601 agtaagttgg tgtttttata agtatattca ttcctctttc aagtttaaca ttatatatct
     9661 ttttatcaga caaagttttt aaactatctt taatcttatt ggctgtatta tcatcaaata
     9721 tgagttcaac acaactttca tctattggta tatcattaaa atataacaaa ccatcttttt
     9781 tagtagcgcc aaaagctttt tcaattgctt ctccaattgt aagttcaggt gttttatctt
     9841 ctggatcctg taaattttta gcagtaactc ttctttcgta agattcattc tctgtatcta
     9901 atataataga tgcagaaata ctgtcaattt gacttatata gtctgaccaa ctatttcctt
     9961 ctgttactat ttgtccagaa ctattttttg taccaaaatt tccacttact tgtgttgttt
    10021 ctaatttaat ttgctttcca gcatctaatt tttttaattg atcataattt ataggaatca
    10081 gtctagagct aaattgatcc attgtgttaa gagctagagg tgaaagccct tttttgggat
    10141 aagtatctcc aggagataga ttattgccaa tttgattttc ttgtgctttg atagttgata
    10201 atgtatctcc atctaacact aaatttgttg ttggtgtcac tttgtacata ggtgcagtac
    10261 ctgtgttgta atatctaaca tttgcattta tatatgcaga ttctcctttg tttatactta
    10321 atccagtatt ccatgattct ccattactat cttgaacagc agttgaatta tctgttgtat
    10381 gggaataatt tgtagttaca ttagctgtga atccattttg atatcctaca ttaacagaca
    10441 caccagctgt attagattca gttttactgt tagtagtagc tctggaaaca gttttacctt
    10501 gatcagtaga ggcatgttca tttgtagata taattaattt ttccatacct actccaacaa
    10561 ttggatatgc tgcaactaac ggatctcttg cttcagtctt tatagccttg tcaaaagaac
    10621 ctgaagcttt ttcataatct gtatatggat ctccagcagt atttgactct aaataatttg
    10681 atacatattt cttatagcct tgttctgcaa aactatcttc ccacttaact gcaattaagt
    10741 ccttaatagt atatccattt cgttcatatg aatctggtat attatcatta tctgtatcca
    10801 aatcttcgtc ttcccaatca gacatcaact ttgggtcaaa gaaattgtta tttgggataa
    10861 atggatcatc tttttctata ttagaataat ctcttaagaa taaattttct tctggtataa
    10921 ttttcttcat accatctaat tcccaataaa gattaggtga tgataaatta tctattgaac
    10981 ctaaattttt atcttgtagc tctattctaa ctttatattc tttacccttt ttcatattaa
    11041 ctttaagtgt atttgatata gtactctcag tatttacttg cattaagaca tcatctctat
    11101 cagttgataa tgtatattca ccatccttag aaggaattat tcttcctgtc catcgtatag
    11161 attttacatc tgatttgtct ttatccagaa gtttatctac tttcttttct tcaaatttta
    11221 aattaccatc ttttatgggt gccattaatt ttaaatcttt aaagtgctca tctgtgaaat
    11281 aatatcccat taatccattg tttgggagta tatcttcatt tacaatttct tttttcttat
    11341 tagaatgatt acttgtacta gtttgagcat atacaggata tactagtgct tgactaacta
    11401 tagctgtaag tgttaaaaaa cttaatacct ttttattcct catttgtatt ttcattgttt
    11461 ctcctcctta aatttgaaaa atattaaatt atttatgtga aaaaatatta aggtatcaat
    11521 gttgcatcaa caattaattt tgttatagta ccatctttgt aagaatcaat tttattgatt
    11581 ttaaatttgc ttccatgatt taaaagcact tcatattcac ctgcataacc tggaatagct
    11641 gatagataag ctccaggaga acctttaggt atagttatac gtagtactat ttttctttta
    11701 gcaaatgcac tcatattcac actaccaata ctagtactaa taaagtttgg ataagacagt
    11761 gcttgtcctt cccattttga tttaaaagca tctatatttt ctagtttgtt aaaatcatat
    11821 tcaggggaag taagagttaa accaaattct tgaggaccag atcttctata tacagttaaa
    11881 ttagttggaa taggttcacg ttttaatgca ttttcaatgt ttgtgatttt agaatctaat
    11941 tctgggttag gattatttac tggaccattt gatattaaat aattattaat tgcagtatat
    12001 cctccacgca tataatcatt tacatcagca agttcattag gtgttaattt attactccaa
    12061 tcattataat ttgctttacc ccaagaatcc cccttactta catcatcttt aaaatcaaga
    12121 ctacttacaa cagatgcttc tgctttaata tagtgcttcc catctataac tatacgaaca
    12181 attttatcta tttttatact atatccttgc tctattaatg tacttacatt gttagtattt
    12241 gtatatggta acataccagt atttctaggt aattttaagt gcataagtaa tggtgtaggt
    12301 ttttcatcac cttttccagg ttcatataaa gaaatatctt taaatccatc ttgcttaaat
    12361 aatttgtttt gtatagtttc tttaaactca ttaaattttt ctaatgaaat ttcgttttga
    12421 ttttctgttc ttattacttt attaaatgca aatttttctg gagattcaaa ataatagaca
    12481 tacataggtt tatctatttt attttttgat atagcatttc gaagttcttt atattctttt
    12541 tctcgagaat ttgcttctat ttgataatca taaaaataat ttcttgtctg agaatattta
    12601 cttatttcta cagaatcttt tttatatgat tctaatgctt ctttttcaga tctttcaagt
    12661 ttttgctcta ttctttctgc ttcttttctt tcccattctt tagccttttc tttatcttta
    12721 agaaaatctt ctggtctttc tataggagcc ttgtaagtag tattgcaaac tttttcacta
    12781 tagctttgta agtcttgtgc ataaatgtta ttaggtaaca aaccacctaa agttagatat
    12841 aatatcaaca atatagatat acaattacta atccttttat gtttcctaaa ttttttcatt
    12901 tattctccct cccaatatta gtttaattaa ctcttgaact ttaatttatt tagattatat
    12961 aatctaaata agaatttttt atataaattt cataaaatat gtaactatat atcataaaaa
    13021 tatgtattta tatgatatgt cagtacaaaa taacaactga atattttaaa gagactattt
    13081 catactttta tgatttaatg agctatcttg ttgaatcata atctaggaac aatggttgca
    13141 atgtctaata gaaattgtat atgatatagt cattatgtgt tttttcacaa aacgattatt
    13201 atatagagga ttcttaggaa ctactttttt tgtataaaaa aagagatggt tcaaattctt
    13261 atcttgagac atctcttttt tctatttatt atgttttaat aatgttcttt aaaatatttc
    13321 tatatgtatt agatatacga catatatggc cattactcat tttaatatta tttttcttta
    13381 ggtcgagaga aacaatatga tatttattaa ctacaaaaga tttatgtaca cgaataaagc
    13441 atgcatctaa atctgataaa gaccttaaac ttttatagaa ttcaaatatt cttgaagtag
    13501 tcactaattt tattttatgt ggaatagcgc ttgtttcaaa atatataact tcatcaaatg
    13561 aaattttcca tagtgaggaa tctgagtaga tagtaaaaaa attagagcga taattttttt
    13621 ctttaacgta tcttttatga gcaattttaa tacaagcttt tattttactt tcagcaattt
    13681 ccatatcatg ttttaatata aagtccataa cttctaacct ataatcgaag atccctaaaa
    13741 tcatttctat atgatttgta agaaatatga ttggactaat ataatctgat tctctaattt
    13801 tttgtgctat ccataatcca tcacataatt cattacttat cttgtatttt gcatctacaa
    13861 ctataaaata tatttttact ttattttttt cagtaagttc ttttaataac aaatttgcat
    13921 tataatataa tcttataaca tcgttatcaa aaccttcttt tattaaaata ttatttattt
    13981 tttcttttag ttttattcca aaacaaacat cattatcaaa aattaatata tccactaaat
    14041 accctcctat aaaaaattca aaagtaaaaa aactaaaagt attttataaa aaatacgtaa
    14101 aataacacta ggagataaat aaaattaagg atagttagaa ttaaggtata tttat
//
LOCUS       DAEQJM010000087        14014 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.088, whole genome shotgun sequence.
ACCESSION   DAEQJM010000087 DAEQJM010000000
VERSION     DAEQJM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14014
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.088"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            305..1198
                     /locus_tag="KRQ43_003227"
     CDS             305..1198
                     /locus_tag="KRQ43_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HBH2743567.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     ILKLEEGDSHHHSNCGCGGNK"
     gene            1198..2592
                     /gene="gltA"
                     /locus_tag="KRQ43_003228"
     CDS             1198..2592
                     /gene="gltA"
                     /locus_tag="KRQ43_003228"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HBH2743568.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLNINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKTKVNA"
     gene            2958..5177
                     /locus_tag="KRQ43_003229"
     CDS             2958..5177
                     /locus_tag="KRQ43_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH2743569.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLRPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5324..6070
                     /locus_tag="KRQ43_003230"
     CDS             5324..6070
                     /locus_tag="KRQ43_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743570.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PTILLADEPTGNLDSKSTDDVLKLFTRINKEQNVTTLMVTHEVYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6070..7950
                     /locus_tag="KRQ43_003231"
     CDS             6070..7950
                     /locus_tag="KRQ43_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743571.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELTILGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEIYFPVKAILLTIVS
                     FMILFLITGPMSLKLLRKKSILELLVGTKKPKKEIKSSRLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYDEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFRLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            8069..9460
                     /locus_tag="KRQ43_003232"
     CDS             8069..9460
                     /locus_tag="KRQ43_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2743572.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9567..10607
                     /locus_tag="KRQ43_003233"
     CDS             9567..10607
                     /locus_tag="KRQ43_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH2743573.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11096..11749
                     /locus_tag="KRQ43_003234"
     CDS             11096..11749
                     /locus_tag="KRQ43_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH2743574.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIHGIIDGMKF"
     gene            11825..12034
                     /locus_tag="KRQ43_003235"
     CDS             11825..12034
                     /locus_tag="KRQ43_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743575.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12174..12740)
                     /locus_tag="KRQ43_003236"
     CDS             complement(12174..12740)
                     /locus_tag="KRQ43_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBH2743576.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSP
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            12901..13554
                     /locus_tag="KRQ43_003237"
     CDS             12901..13554
                     /locus_tag="KRQ43_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBH2743577.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13712..13888)
                     /locus_tag="KRQ43_003238"
     CDS             complement(13712..13888)
                     /locus_tag="KRQ43_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743578.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT         5490 a         1388 c         2358 g         4778 t
ORIGIN      
        1 gtatttataa aatttttgtt acaaatttgg cataatatag tatactttaa gtgtgtatta
       61 ggttaaatct ataacaaatt agacgtatga tatagactta gtgtttattg gcatttacaa
      121 gaaatttgtt aatatcaact atttgtagtt tgggcagtta taattactat aggggggatg
      181 tccaatacaa aacaatcaac caagaactaa tattatatta taaagagtta tagttttgtg
      241 tgtttatgtt tttaattaaa tttaaagtgg gaaaaatata tttgttagaa tggagaatag
      301 cgagatgagt aataaaatag ttagtaagag acaattaaca gatagtattt atttaatgga
      361 aatagaggca cctagagttg caaaatcttc tcaaccaggt caatttataa taattaaaaa
      421 tgatgaaaag ggagagagga ttcctcttac aatagctgac tatgatagag aaaaaggaac
      481 agtaactatt gtattccaaa cagttggtgc ttcaactaaa aagttagcaa tgtttgaaga
      541 aaacgatttt gtaatggatt ttgtagggcc attaggacaa gcaagtgaat ttatacatga
      601 agatatagaa gaattaagaa ataaaaagat attatttgta gctggtggag ttggttctgc
      661 tccagtttat ccacaagtta aatggtttaa agagcatgga ttagatgtag atgtaataat
      721 tggtgcaaga actaaagaat taattatatt agaagatgat atgaaaaaag tagctaaaaa
      781 tgtatatgta tcaacagatg atggtacata tggatttaat ggaagagtta cagacctatt
      841 aaaagattta gttgataatc aaggtaaaaa atatgaccaa gcaatagtaa ttggaccaat
      901 gataatgatg aaatttatgt gccaattaac taaagaacta aatataccta ctatagtaag
      961 tttaaataca ataatgatag atggaacagg tatgtgtggt ggttgtagag ttagtgttgg
     1021 aaatgaaact aagtttgcat gtgtagatgg tcctgaattt gatggtcatt tagttgattt
     1081 tgatcaagca atgagaagac agtctatgta caagactcaa gagggaagag ctattctaaa
     1141 acttgaagaa ggcgatagtc atcatcatag taattgtgga tgtggaggta acaaataatg
     1201 gatgctaaaa aagtaaaagt accagttaga gaacaagaac ctgctgtgag agcaacaaat
     1261 tttgatgaag tatgcttagg gtataataaa gaagaagcta tggcagaagc taatagatgt
     1321 ttagcttgta aaaaaccaaa atgtgtgggt ggatgtccag taggaatcga cataccaggg
     1381 tttataacaa aaattaaaga agatgatata gaaggtgctg ctaaagtaat agctaagagc
     1441 agttcattac cagctgtttg tggtagagta tgcccacaag aaagtcaatg tgaaggtgta
     1501 tgtatacttg gaataaaatc agatgctgta tcaataggta aattagaaag atttgtagca
     1561 gattggtcaa aagaaaatga cataaattta tctgatacag agcctaagaa aaatcaaaaa
     1621 gtagcagtaa taggaagtgg tccagcaggt ctagcttgtg ctggtgattt agctaaaaaa
     1681 ggctatgatg taacaatctt tgaagcaatg catgagccag gtggagtttt aacttacgga
     1741 atacctgagt ttagacttcc aaaacaagct gttgttcaac ctgaaataga caatataaga
     1801 aaattaggtg taaaaataga aactaatgta attgttggta aaacaattac agtagatgaa
     1861 cttatagaag atgaaggatt tgaagctata ttcataggtt caggagctgg tcttccaatg
     1921 tttatgaata taccagggga aaatgcaaat ggagtgtttt ctgcaaatga gtttttaact
     1981 agagtaaact taatgaaggc ttatagagat gactatgata cacctattag ttctggtaaa
     2041 aaagttgctg tagtaggtgg tggaaatgtt gctatggacg ctgctagaac tgcattaaga
     2101 ttaggttcag aatcatatat agtttataga agaagtgaaa aagagcttcc agcaagagct
     2161 gaagaagttc atcatgcaaa agaagaaggc attatattta atacattaac aaatcctaag
     2221 gaaattttag tagatgaaaa tggatatgtt aaaggtatgg tttgtataag aatggaatta
     2281 ggagagccag atgattctgg aagaagaaga cctatagaaa tagaaggttc tgaatttgta
     2341 cttgatgtag acacagttat aatgtcactt ggaacaagcc caaatccact aatatcttct
     2401 acaacaaaga gtcttaatat aaataagaag agatgcttaa taacagatga aaatggtcag
     2461 acttctaaag agggtgtatt tgcaggtgga gatgctgtta ctggagcagc aacagtaata
     2521 tctgcaatgg gtgctggtaa aacagcagca gcatcaatag atgaatattt aaaaacaaaa
     2581 gttaatgctt aatttgtaaa ttaaagagag ggtgtctcaa aatgaacttt ttagttcatg
     2641 aggcactttt tttgtacaaa atcaaatatg ttttaatcat ttcaacaatg aaaatttcat
     2701 tcctgtagaa agtctaactt ttaagtctta gtacaatctc tattttgatg taggcacttt
     2761 tttagatggt ttaataattt atcagttatt attgtaatat ttgatactaa gtaacataac
     2821 tttgtctaac tatgataaaa tagttataca ataaaggtct tgtaaggagt gaataatgtg
     2881 tggctaataa aatcagattt gtcaaatcta acattaaata atagaaaaat aaattgtgta
     2941 attaatggta ttttaatatg aaaaaaagag aaaaagtatt tgatgggcta gtttttaagc
     3001 atatattaat cttattaata ctattagttt tgattgattt aacaagtacc atcatatatg
     3061 caagtaactc tatggaaatt acttctagaa atatgattga ggcatcaaaa agagaacttg
     3121 aaaactattt agaagtaaac atatctttat taaaagctct tagtcaagat gatagatttt
     3181 ctaatggtga aacatcacta attgaaaagg gaaaattatt aaggccatat caaaaggaat
     3241 ataatctttt tatgattggt ataacagata caaaaggaaa tgcttcaagt acatataggg
     3301 aaaatgttaa ctcaataaaa gataagccta gttttgagaa agcaattaaa acaaagcaag
     3361 tagtagtttc agatattgaa gtcagtaatg taacaggtga caaagtattt atcatatatg
     3421 taccaattgt aaaaaataat gagatgattg ggaccatttt tgcttctttt tattttcaag
     3481 atgtaaataa tttaataagt agaagcaatt ttgatgattc tattaaattt ctaatgatag
     3541 ataaagatta tactattatt tctcatccaa acaaaaaata tgtaaatgat aaaagtaaga
     3601 tgcttgattt agaagggaat attataggaa ccactaaaag tgaaatctta aaaaatataa
     3661 ataaaaaatg tcaaggtgat tttttatctt gggataattg gagattatat aatgtaaaat
     3721 atacgaacat aaagtggact aattggactt tagtatcaaa atgtaatata tttaagaact
     3781 ttaaaaatct aatagttaat tttatgataa agttgtattt ttatatagta atatttatga
     3841 tattgtggaa attaagtaat gctaaattaa tagaacaact taaaaaattg gcttattatg
     3901 attctttaag tggaataaaa aataaagaaa agtttagaaa agattctatg tatattttaa
     3961 agaattatta tcaagataat ttttacttag tacaattgga tgtcaataaa tttaaatata
     4021 taaatgagat gtttggatat gctgaaggga ataagatatt aattcatata tcacaggttt
     4081 taaataataa tacaaataaa tatgaaattt gtgctaggat ggataatgac cattttatat
     4141 tgttgattgc ttgtaatact gaagatgaac ttttaaatag attatctaaa ataaataaag
     4201 aaatttgtaa cttaaatact actaactcat ctaagtataa aattgttatg tcaagcggaa
     4261 tatataagat tactaaaaag gatgatatta aaaagattga cctgttaatt gatagagcaa
     4321 atattgcagc aaaaagtaaa aaggaaaaat atgaacattc atattcgttt tttaatgaag
     4381 atacaagaaa tcgattgtac aaggaaaaac gattggaaga taatatgaat aaagctttag
     4441 aaaaaggtga atttatagta tattatcaac ctaagtatag tttagatgat gtaaatgaaa
     4501 ttgaaggagc agaagccttg ataagatgga atagtccaga atttgggttt atttcaccta
     4561 tagattttgt acctttattt gaaaagaatg gttttattgt aaatattgat atgttcgtgt
     4621 ttgaagaagt atgcaaaaca ttaaacaagt ggataaataa agggtatact cctgtaccaa
     4681 tctctgtaaa tatgtctaga gttcatttat atagggataa ttttatagaa aatataactg
     4741 atttgataag taaatacaat atatctcctg agtttattga acttgaacta acagaaagtg
     4801 ttgtgtttga taatttaaat atattgattg atataatgaa aaagattaaa gagataggat
     4861 tccttatatc aatggatgat tttggttcgg gatattcatc tttaaatctg ttaaaagacc
     4921 tttcttttga tattttaaaa ttagatagag gatttttaat cgaaacaaca gatacaaaac
     4981 gtggaaaaat tattatttct aagattgtgg aaatggcaaa agcgattgat attaaagtaa
     5041 tctgtgaggg cgtagaaact tatgaacaag tagagttctt gaaagagata ggttgtgata
     5101 aggttcaagg atacttattt gctaaaccta tggtattaga tgaatttgaa aaacacttaa
     5161 actttaaatt tgattaatca ttaataatta ttagactata atatacccta acaacttact
     5221 tacaaatatg taagttaatt gttagggtat ttttatggtt aaagtagtat attcacgata
     5281 ttatggtatt gtagtaaaaa taaaaaatta tggagaatat aaaatgaaca tattgagtat
     5341 tagaaatata tcaaaaacat attgcggaaa tattccattt aaagcattag ataaggttag
     5401 tctaaatata gaaaagggag aatttgtgtc tgttatggga ccatctggaa gtggtaaatc
     5461 tactctttta aatataatat ctacagttga tagacagagt gaaggtgagg ttgtattaga
     5521 tggatatgat gtaagtaaat tgaaaggaga aaaacttgct gaatttagaa ggaaacaact
     5581 tggttttgta tttcaggatt ttaatttgat tgacacttta actgttggcg aaaatattat
     5641 gttgccactt acactagagg gggcaagtat caaagatatg aatatacaaa ctaaaagtat
     5701 atctaaattt ttaggaatag ataaaatttt agatagaaaa acctatgaaa tttcaggagg
     5761 tcaagctcaa aggtgtgcta ttgctagagc tattataaat aaacctacca tacttcttgc
     5821 agatgagcca actggaaatc ttgattcaaa atctactgat gatgttttga aattatttac
     5881 taggataaac aaagaacaaa atgtaacaac acttatggta actcatgaag tatatagtgc
     5941 aagttattca gatagagtaa tttttataaa agatggttgt atatatacag aaataaaaaa
     6001 atctgaaagc agtaattctt tctattctga tatactagct gttttgtctc aaataggagg
     6061 tgtaagatag tggattttag aaagtttgct tataataata tagttagaaa tttcagggca
     6121 tatttagcat attttttaag ttctgttttt tctataatga tattttttgt ttttgcagtg
     6181 tctatgttcc atccgattat aacaaaatct ggaatgcaga gtggttctac tgcatttatg
     6241 gctcttatga cttcagaatt aacaatatta ggttttagtc tactttttat attgtactct
     6301 ttaggaaatt tcttgaaata tagattgaaa gattttggag tattgatgat aattggaatg
     6361 agcaacagac aactgaaaaa attgatatta attgaaaatt tgataatagg atttttagca
     6421 gtgatgttag gaatattact tggtttatca atttcaaaat tgtttttatt gtatttaagc
     6481 aaactgtttt atatgaattt aactgaaatt tattttccag taaaagcaat actattgact
     6541 attgtatcat ttatgatttt atttttgata acaggaccaa tgagcttaaa attattgaga
     6601 aaaaagagta ttttagagct tttagtaggt acaaaaaagc ctaaaaaaga gataaaatct
     6661 tcaaggctat ttggaataat tggtgtaata tgtcttatat taggatatgc tatgatacta
     6721 tttggcaata agttaaaaat aaatggaggt atgtatacaa cagcactatt aattactttg
     6781 gggatatttt tatttttttc tcaatttact attttgatat taaagtattt aaaaaataaa
     6841 gaaaaatttt ataagaacaa agtaaatatg ttacttataa gtaatttgat atataaatta
     6901 aaggataata cacgattgtt atttttaata acaatacttt tatcggctac tttagtagca
     6961 tttacaacaa cttcaacact tgtaagttct caaggagaag cttctaaaaa taatttccca
     7021 atggtttact catatttttc agagcataat aatgaaaaag aatatgaaga actacaacaa
     7081 attagagaag caatcaaagg atatgattat aaggagttaa gttttcctgt acttaaatat
     7141 aatagggaag tcttactaag tgtaaagaat tataacaaat tatcaaagga attgggatta
     7201 gataaaatta gttcaaagtt agaaaaatat gaagggatta taattcctag tagcaattca
     7261 caagaacata taaattcttt aaaacaatta aaaaattata gtataaaaaa tttaaatata
     7321 gaagtaaaaa aatcaaaaaa taaaataatt tttcctacag gactgtttag taaagttgta
     7381 gttataagtg atgacttata cgatgaagta aaaggtgaat tttcaaaaat taattttcat
     7441 ggatttgatt ataaaaactg gcaaagcagt gcaaagataa ctgaaaattt aaaagaaaaa
     7501 cattttaatt tggatagaga atataacagg tcatattttt taacattacc agatatgtat
     7561 ttagtagagt tacaacaaag taaaattctt caatttatgg gtgtttttat aggagtgata
     7621 ttatttatag cagtttttag ttttttatac ttcagattat atacagacga gatagaagat
     7681 aatgtaaagt acaaaaaact atcaaaaata ggtctatctt ttaaaaatat gaataagatt
     7741 gttagtatag agataggtac attgtttttt ataccgtatt ttatagcaat tataaatagc
     7801 ataatttctt tactgttttt aaatcaagta ttaaataata gttttaggtt agaaaatttg
     7861 ggtatattac tactgatatc atctatatat tcactttatt tttacttatt aaaaaaaatt
     7921 tatactagaa aagtttggtt ttttgattaa agtggtatat aatagatata taaattaata
     7981 tttaaaaagt agttaatatt aggggagggc atttgcacct cccttgtaat atgtggaaaa
     8041 ttgaatatta gaagaaggag gagacttgat ggaaaatcaa caattattag gaacagaacg
     8101 aattagtaaa ttactactaa aatattctat accagctata ataggtatgt tggtaaatag
     8161 tttatataat gtagtagata gaatttttat tggaaatata ccaggggttg gaccacttgc
     8221 aataacaggt cttggtgtaa caatgccaat aatgacaata atacttgcat ttgggatgtt
     8281 gataggtata ggaactacta ctaccatatc aataaaactt gggcaaggta aagtagaaga
     8341 ggcaagaaaa cttataggaa atgcaatgac gttatctgta ataacaggaa ttatcataat
     8401 gatacttgga atattatttg caaataaaat acttacattg tttggagcaa gtgaaaatac
     8461 tttaatatat gcaaaatcat atataaatat tatattatta ggtacagtag taaatcttct
     8521 ttccttttct ttaaaccact caataagagc tgatggtagt cctaaaattt cagcaggaat
     8581 aatgatagta ggatgtttaa ctaatatagt tttagactgg atattaatat ttggattcaa
     8641 tttgggaata caaggagctg caattgctac agtaacttct caggctctta cagctatttt
     8701 aactataggg tattatataa gtggaaaatc aaacttacga ttcagtaaat ctaatctaaa
     8761 attagataaa aagctaataa aagcagtgtt tgcaataggt atgtcgccat ttgcgatgca
     8821 acttgcagca agtttagttc aagtaatatc aaatattgca cttaaaactc atggtggaga
     8881 tttagctata ggggctatgg ctactatttc ttccattgca atggtatttt tgatgcctat
     8941 ctttggaata aatcaaggag cgcaacctat tataggtttc aattatggag ctgaaaaata
     9001 tgatagggtt aaaaaagcat atttaggttc attagtagta gctactataa ttttatgtat
     9061 gggtatggta gtagttatgc ttttcccaga agctattata ggtatattta ataaagaccc
     9121 tgaacttatg aatatatctg ttaatggatt aagaatatac ttacttatgt tgccaattgt
     9181 aggcttatca gttacaggaa caaactttat acaatctata ggaaaagcaa aaatggctat
     9241 gttattgagc cttttaagac aagtaatttt attgatacca gcagtattaa ttcttcctac
     9301 attcttaggt ttacagggtg tatggacagc tcaaccagtg tctgatttta tagctacagt
     9361 aattacaggt atagttgtat ttagagaatt aaaaagatat actcctaaaa ctgaaaaatt
     9421 aaatgaaaat gaaagactaa atgagataac tactgagtaa aaatataaat tcagataatt
     9481 gagcaagaaa ttgcaaaaaa tacgattata tgataaaata aaaccgctgt caaggataag
     9541 agaaattcta attatggagt gattttatgg aatttacaaa gaaaagcaaa ttaaaaaata
     9601 tgtatgtaaa catgaatgta gctagaatgt tgtctaagat aaatgagtat aagggtaggc
     9661 aactgcttta caaaaaacaa ccaaaagaaa ttttagaaaa cctagaaaaa aaatctttag
     9721 tagattgttc tgaatctaca tacattggaa atcaaagaga tagtagtaat tttaatctag
     9781 aaaagttgat aagtaatgaa gttacaccta gaagtagaga ggaattgagt attgttgaat
     9841 acagagatgt ggtaaaaact attaacagtg cttatgagag tattcccatc agttcacaaa
     9901 cgattcttga gcttcatggg tacttatata aattttcatc tactagagga ggaagttata
     9961 agtcagataa tgattttatt gaacacaatt taaaacctag cgaatttata agtattgatt
    10021 caagtgtcaa taaagttgaa aaagctgtag aagaaatatg tgaagcttat aatacattga
    10081 tagaggaaga tgaaattgat atattaatat taatttctgc atttgtgtta gatttcatat
    10141 tgatacatcc attcaaagaa ggtaatataa aaatggcgag agtacttatc ctattgttac
    10201 taaataaaaa tgggtatgaa gttggaagat atataagttt aggaaagata tttgatgata
    10261 gttcatatga atattatagt aatttaaatt atttgaaagc ctcaataggt agtgaaaaag
    10321 cagatatgaa tgcatggatt gagtattttt tagagacgat attaactgca tatgagaagc
    10381 tggatgatag tttaaatata tctgataaga aaagacaaac aaaaactagt agaatagaaa
    10441 aaataataaa ttctaccctt ggatatttta caaaagaaga tataagagat ttatgtcctg
    10501 acattccaga acctactata aatagagttt ttaataatct aagaaaacaa gataagatag
    10561 aagttgttgc aagaggaaga agtgcaaaat ggaagaaaaa atattaaaaa atgtttaaat
    10621 aactaaaatg gtatagtgtt ttacactata ccatttttaa tgtcattagc atgagcaata
    10681 atttaacaac ttaagcaata tcaattttat ttattgatta tttttgaact gaaaaatggg
    10741 gttatatggt atactacaat aataattaat tttggatgag aatatataac gttacagaat
    10801 atcttaggag tatatgtata aaaaatataa taaaagtgtg aggtttagta attaacaaat
    10861 tatgtggctt cacacttttt tataaaataa aaatacttag cagaagaata ttttagttga
    10921 tatgtttata agatagtact tgtttgggta aaagtataaa tagtaaaaaa gtagaagtaa
    10981 tgtgtataaa aacataagtt acattctgta ataatagtta ttttataatt caacaaaaga
    11041 atagaatggg tatatttgtg aaataataat ataaaataat cttaggagtg atcttatgaa
    11101 gaaaaaatta ttatatataa atgtaaattc aaaacctgaa gacttatctt caagtaaaac
    11161 tgtagcaaga aaatttataa ataaatttat ggaaaaaaac aaagattttg aggttgaaga
    11221 gatagacctt tataaagaac atataccgag acttgagtat cagtactttg aaaaaagaaa
    11281 tagcatagtt agtgaagaaa atgctaaaaa tttagacgat aaggatagaa aagagcttac
    11341 aaagattaga aatctttgtg accaatttgt gagtgcaagt gtttatgtaa tagcagcacc
    11401 tatgtggagt ttatcttttc cagcaccact taaagagtat atagattgta taattcaaga
    11461 tggaaaaact atatcttttg aaggcaatga taaaccacaa ggaattttaa atgatattga
    11521 tagaagtatg gtatatatac aatcttctgg tggacacata ccatgggtct tgaagccagt
    11581 tatgaataaa gggttaaatt atgtggaaag tattatgaaa tttataggaa ttaaaaaatt
    11641 tgatgaattg ttagtagatg gaactggaac tagtgaagaa gaaagacaag ctgcaataga
    11701 aaaagcatct gaaaaaatac atggtataat agatggtatg aaattttaat tataatattt
    11761 tattaaaaat ataaaggaaa aacctctttt aatgtagaaa cttatattga aggaggcgag
    11821 aatcatgcga gaagaaaaaa gtaatgaaaa gtatgattgt tattggtgta atcaagaaaa
    11881 taatttctgt gtagaaataa aagataatat agtaatgata gatgatggca ctggtacgtt
    11941 aaaacaagcc gttttcatag ggtataaaca aatccaaatt aatttaaatt gttcacattg
    12001 tcaaaactta aatagaataa aattaaattt gtagaatttt aaaatggaaa ttattgaagg
    12061 aattaaaaat agaaagtgtt aatatttaga ctgaaaatta tattttatac aataaaagtt
    12121 tatttaaata acattgtatt ttaatattta ttttcagtct tactttatta aaattatttt
    12181 ttggttatgt ctggaaaata tctgtctact aatttttctg aaatattttt taattggtca
    12241 gccattgaag tcagacttaa taaggctatc aataaatcat ctttattttc tggatttata
    12301 ctaatatttt caaaattaga ctctataaag tccggtatat tctttctttg attttctttt
    12361 attaacatga atttttcgta acatgaaact aaatcttttt cactgaaatt atccttttca
    12421 tacacaccat gtaagattct tttaatttct tgtattgtaa gtgtattttt catagaataa
    12481 ataattatca tctgtaaaat ttgttcttta gtatactttt ttcccttaac tggtttgatt
    12541 aatccctctt tgctgtaatt atttatcatg gttttagtaa gaattttatc actttcaaat
    12601 cttttattag gagaaagttt attgtcaatt agagaaataa tttgatccat atataagtca
    12661 atagagggaa tatcgtttga agttatatct gcattattta gtgtttctag tattatagta
    12721 ttaagttcat tattcatcat atgttacctc cataatatat ataatacact aaattagaaa
    12781 gtaaaacaat attaagactt gtaaaaaaaa cataaagtgg tataattaaa tatataatat
    12841 agtaatgaaa actatattta tgaatctgat ttttaaaata cataattgta ggaggacgaa
    12901 atgtatcaat tttttttaaa gggtagagac ccaataagca gtttaactca ttttataggt
    12961 gcttgtttat ctcttttagc aactataatt ttagtttttc aatctgttac attacaggaa
    13021 acttctctct tgatgatagt atctgtatcg gtatttggac tttcactaat tgctttatat
    13081 agtgcaagtt cgtattatca ttttttaaag gggacaccag aacaagaatt gttttttaga
    13141 aaagtagacc atgcaatgat ttatgtattg attgctggct cttatacacc aatatgtctg
    13201 aattttatgg aaaaaaaaga aggcataata tttgttacag caatatggat agttgcattt
    13261 attggcataa taataaaaat attttggatg gatgcaccta gatggttatc taccagtata
    13321 tatttactta tggggtgggc aattgttttt gatataaatg cattcaattc aattcctaag
    13381 gattgcctta gactattaat tatggaaggt gtatcttact ctataggtgc aattatttat
    13441 ataattaaaa agcctaatat aagtcctgag tttggatttc atgaaatatt tcatattttt
    13501 attatgatag gttctttatt tcacttttta gcagttttat tgtatgtttt atagttttaa
    13561 aagatttgat taattgatac taaaattcta caatgaataa aatggaactg ccttatatag
    13621 attatatctt cgacaataag acagttcctt attataaata ttaaattcta cttataataa
    13681 aattttgata aaaatagtcc attcaaaatg cctattccat aattccttta atgtactttt
    13741 catttacgac atatagtttg aatttatgta ctataattat atcctctaaa ttctctgaaa
    13801 cactaacaat tctgacacat ttgtttctaa tttctacagg taaatctaaa tcatttgtta
    13861 aattcacata gtcatcatat ttatacataa aatcatccct ttacattaag atatacttat
    13921 tatactatat tttaataagt ttttttaaat tattacaatt tttcccgaaa tttcattttt
    13981 tatacataaa atttccaaat taggtaaaga ttaa
//
LOCUS       DAEQJM010000088        13515 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.089, whole genome shotgun sequence.
ACCESSION   DAEQJM010000088 DAEQJM010000000
VERSION     DAEQJM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13515
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.089"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            111..1514
                     /locus_tag="KRQ43_003239"
     CDS             111..1514
                     /locus_tag="KRQ43_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743579.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            1541..3085
                     /locus_tag="KRQ43_003240"
     CDS             1541..3085
                     /locus_tag="KRQ43_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH2743580.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            3116..4507
                     /locus_tag="KRQ43_003241"
     CDS             3116..4507
                     /locus_tag="KRQ43_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HBH2743581.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            4700..6196
                     /gene="abfD"
                     /locus_tag="KRQ43_003242"
     CDS             4700..6196
                     /gene="abfD"
                     /locus_tag="KRQ43_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HBH2743582.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            6331..6606
                     /locus_tag="KRQ43_003243"
     CDS             6331..6606
                     /locus_tag="KRQ43_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743583.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            6630..7937
                     /locus_tag="KRQ43_003244"
     CDS             6630..7937
                     /locus_tag="KRQ43_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH2743584.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            7957..9075
                     /locus_tag="KRQ43_003245"
     CDS             7957..9075
                     /locus_tag="KRQ43_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH2743585.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            9362..10282
                     /locus_tag="KRQ43_003246"
     CDS             9362..10282
                     /locus_tag="KRQ43_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBH2743586.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFIPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            10397..11554
                     /locus_tag="KRQ43_003247"
     CDS             10397..11554
                     /locus_tag="KRQ43_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH2743587.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(11639..13138)
                     /locus_tag="KRQ43_003248"
     CDS             complement(11639..13138)
                     /locus_tag="KRQ43_003248"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBH2743588.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
BASE COUNT         5213 a         1625 c         2529 g         4148 t
ORIGIN      
        1 acaagataaa atttttttaa tcagaaatgt taatttaata acaaaataga gtattgggga
       61 gaaaggagaa atatattttt taataatatt tgttaattta ataacgaaaa atgaaaggga
      121 gtgatttagt gaagtttgaa ttgatggatt ttttaatgaa tccttttgtc cttatgtttg
      181 ctgcagtaat tacaggaatt ttatttggaa aaattaaatt tgggaagttt aattttgggg
      241 tatcaggagc attatttaca ggattattta ttggatggct tgcatatagc ttggggaatc
      301 taataatagc aaaaggagaa acagcagcag gatataaggc agcaactgta atgatgggga
      361 atggaattat ttcttctgac ttctttgatt tctttttaat aatatttgtt gcagcagttg
      421 gtctattggc agcaaaagat atgaaagctg tattaaagaa gtatggagca agatttgtaa
      481 ttttaggagt tcttataact tttataggtg gctctatgac ttatgcaatg actttactat
      541 caagtgataa aggaagtagt gcttatgaag tttctggcgt ttacacagga gcattaacaa
      601 gttcgcctgg attagctgct gctttagaaa cagctggtaa acatgcagaa gatgtatcaa
      661 aagaatttga aaaagcttca ataaaagata aaaaagaaat tttaaaagta gtcgacccag
      721 aaggcaaatt ggatgtgaat acaactacat cactgactca agagcaaata gataagtata
      781 ttgcatatgc tgaagctggt gttggtatag gtcatgcagt cgcatatcct tttggagttt
      841 taatagtaat cttaggtgta aatttccttc caaaattatt taggatggac ctaaaagaag
      901 aaagaagaaa atatgagaag gaaatgaagg aagcaagaga tagtgtttct ggtaaaacga
      961 taccagaagt tccatttaat ataataacat ttttcttgac atgtttagct ggatacttag
     1021 ttggaggaat acatgtattt atgggaccac tagggtactt cacactaggc gcaacaggag
     1081 gttcactaat tgtatctcta gttcttggat atataggtaa gataggggta gtaaatttca
     1141 gaatggaaga aaaggtttta aatattttaa aacaaatagg gctagtattt ttcttagcaa
     1201 tagttggatt aagatatggt ggaaaagtag ttgattcaat tatgacatct ggtatgcacc
     1261 tagccttagt agcaatagca gtaggtgtta cagctatgat gataggattc ttagttggca
     1321 aatacgtatt taaattaaat tggattttat tatctggagc tgtctgtggt ggtatgacat
     1381 caacaccagg tcttggagct gctgttgatg ctcttgatag tgatgaccca gcagcaggtt
     1441 atggtgctac gtatccattt gcattattaa ctaaagttat attggttata gttttacaca
     1501 aacttccaat gtaaataaga ttttatatgg ggggatattt atgaataatg aaggagcatt
     1561 tgaagaatta agtggaagat taagaaataa agaattgtgt gatttaataa tgaatgcaga
     1621 tgaagctgct aaaattatag aggatggcat ggttattgga gttagtggat ttacaccttc
     1681 aggctatcca aaagcagtac cattagcagt ttcagaaaga gctaaaagtg gagaaaagat
     1741 aaaattaacc gtatattcag gagcatcttt aggcccagaa gttgatggag catggtcaga
     1801 agcaggtata attgaaagaa gacttcctta tcaaactaat tcaatactta gaaataatat
     1861 taataaaggt gttgttgatt atatagatat gcacctaagt cattctactc aatttttaaa
     1921 ttatggaact atacctaaag tagatgtagc tatagtagaa gcacttgcaa taactgaaga
     1981 agggaatatt ataccaacta gtgggatagg taattctcca tcttttataa aaagtgcaga
     2041 taaagtaata gtagagataa atcttgcaaa accaatggaa atggaaggta tggcagatat
     2101 atatattacg gaaaatccac caaatagaaa accaatagaa ataaatcatc ctaaggatag
     2161 aattggaaca acatatatac cttgtggttt ggataaaatt gcaggagtag taattaccaa
     2221 tatgcaagat aagacccgtc cattgggggt tgtagatgaa gcttcgaaaa aaatatcaaa
     2281 taatattatt gcttttttaa gagaagaagt aaaggcaggc agattatcaa agaatttact
     2341 tcctcttcaa tctggtgtag gaagtgtagc aaatgcagta ttatatggat tatgtgaatc
     2401 tgaatttgaa aatttaactt gttatacaga ggttgtacag gactctatgt tggatttaat
     2461 aagaatgggt aaagttacaa tggcatctac tacatctgta agtccatctc cagaaggatt
     2521 aataaaattt gaaaaagata ttgatttttt taaggataag attatattaa gacctcaaga
     2581 aattagtaac aatccagaaa tagccagaag aattggtgta attgcaatga acactgcaat
     2641 tgaagttgat atttatggaa atgtaaattc tactcacata atggggtcaa agatgatgaa
     2701 tggaattgga ggttctggtg attttgctag aaatggagca ataactatat ttagtactga
     2761 gtcgattgca aaaaatggtg atatatcatc aatagtacct atggtatctc acgtagacca
     2821 cactgaacat gatgtaatgg taattgtaac agaacaagga tatgctgatt taagaggtct
     2881 tgcacctaga gaaagagcta taaaaataat agaaaattgt gcccatccag attataaaga
     2941 acaacttagg gattatttaa atagagcttg taaaagtgga gcaaaacaaa cacctcacat
     3001 attggacgaa gctttatcat ggcatagtaa atttatgagt acaggtacaa tgaaaaaggc
     3061 tgaaactttt aaaagtgcat tataaaatat ttaataaatt ggaggtagat tttaaatgga
     3121 aaaagcagtg gaaaactttg aagatttaag taaggaatac attaatggtt atattgagag
     3181 agcaagaaaa gctcaaagag agtttgaatg ttatactcaa gaacaagtag ataaaatagt
     3241 aaaaatagtt ggaaaagtag tgtattataa tgctgaatat ttagctaaac ttgctgtaga
     3301 agagactgga atgggagtat atgaagataa ggtagctaaa aataaaagca aagcaaaagt
     3361 tatatataac aatttaaaag ataaaaaatc agttggtata attgatatag atagagaaac
     3421 tggaataaca aaggtagcta aaccagttgg agtagtagcg gcaataactc cttgtacaaa
     3481 tccaatcgtt acacctatga gcaatgcaat gtttgcactt aagggaagaa atgcaattat
     3541 tatcacacct catcataaag caattggatg tagtacaaaa actgtagaga tgattaatga
     3601 agaattagaa aaaataggag ctccagaaaa tttaatacaa atacttgacc aacaatcaag
     3661 agaaaataca agaaatttaa tttcatcagc agatgtagta attgccactg gaggaatggg
     3721 aatggtaaaa gctgcgtact caagtggaaa accagcactt ggtgtagggg caggaaatgt
     3781 tcaatgtatc atagatagag atgtagacat taaagaagca gtacctaaaa tcatagcagg
     3841 aagaattttt gataatggta tcatttgttc aggtgaacag tcagtaatag tagcagaaga
     3901 aatgtttgat aaaataatgg atgaatttaa aaataacaaa ggttttatag ttagagataa
     3961 agtacaaaaa gaagctttca gaaatgctat gtttgtaaat aaatctatga ataaagatgc
     4021 agtaggtcaa tcagttcata caattgcaaa aattgcaggt gttgagatac cagaagatac
     4081 aaaaataata gtaatagaag ctgatggacc aggagaagag gatattattg caaaagaaaa
     4141 aatgtgtcca gttatatctg catacaagta taaaagtttt gaagaaggtg tagctattgc
     4201 aaaagcaaat ttaaatgtag aaggaaaagg acatagtgta tctatacatt caaatacagt
     4261 taaaaatata gaatatgcag gagaaaatat agaagtatca agatttgtta ttaatcaatg
     4321 ttgtgctact agtgctggag gaagtttctt taatggtctt gcacctacta atactctagg
     4381 ttgtggttct tggggaaata acagcatctc tgaaaatctt gattataagc atctaattaa
     4441 tatttctaga attgcttatt atatgccaga aaatgaagtc cctacagatg aagaactttg
     4501 gggataaaac ttagacaaaa aatattcatt ctaaattaaa gtaggaatat attttaattt
     4561 agaatgaatt taagacataa attaaattta aattagttta ttggactaaa tttaaaatat
     4621 taagagacat atagaagaag gaagtattat aatttaaaat aaataaaaaa atctataaaa
     4681 gagaaggagt ggttttatta tggcattaat gacaggagct caatatattg aaagtttgag
     4741 aaaattaaat actaaggttt atatgtttgg tgaagaggtt aagaattggg ttgaccatcc
     4801 tatgattaga ccatctataa attgtgtagc agcaacttat gacttagctc atgacccaga
     4861 atatgcagat ttaatgacag ttacttcaaa tatcacaggt gaaaaaataa atagatttgg
     4921 tcatcttcat caaagtgttg atgatttgat aaaaaaagta aaaatgcaaa gactatgtgg
     4981 tcaaaaaaca gcttcttgtt tccaaagatg tgttggtatg gatgcgttta atgcagtgta
     5041 ttcaacaaca tttgagtgtg ataaagccca tggaactaat tatcatgata attttgtaaa
     5101 atacttaact tatatacaag aaaacgattt agtagttgat ggagctatga ctgaccctaa
     5161 gggagataga agtctatcac ctagtgctca acctgaccca gatatgttcc ttcatatagt
     5221 agaaagaaga gaagatggga taattgtaag aggagcaaag gcacatcaaa ctggttcaat
     5281 aaattcacat gagcacctta taatgcctac tataagtatg actgaagcag ataaagacta
     5341 cgctgtatca tttgcagttc cttcagatgc tgaaggtgtg tttatgattt atggaagaca
     5401 atcttgtgac accagaaaat tagaagaagg tgcagatgtt gatttaggaa ataaggagtt
     5461 tggaggtcaa gaagctttag tagtatttga taatgtattt gttccaaatg atagaatttt
     5521 cttatgtgga gaatgggatt tctctggtat gttagtagag agatttgcag gataccatag
     5581 acaaagttat ggtggatgta aagtaggagt aggtgatgta ataataggag cagcagcttt
     5641 agcagctgat tataatggag caaacaaagc ttcacatata aaagataaac taatagaaat
     5701 gactcacctt aatgaaagct tatattgctg tggtatagca tgttcatcag aaggtcacaa
     5761 aacagaagct ggaaactatc aaatagattt acttcttgca aatgtgtgta aacaaaatgt
     5821 aactagattt ccttatgaaa tagtaagact tgcagaagat atagctggag ggcttatggt
     5881 tactatgcct tcagaaaaag actttaaatc agaccttaaa gttggaacaa gtggaatgac
     5941 tattggcgaa gtatgtaaca agtattttaa agcttcttca gtggcttcaa cagaagaaag
     6001 aatgagaata ttaagattct tagaaaatat atgtcttggt tcatctgctg ttggttatag
     6061 aactgagtca atgcatgggg caggttcacc acaagctcaa agaataatga tttcaagaca
     6121 aggaaacata aatcaaaaga aagaattagc taagaaaatt gcgggaataa aaaaagagga
     6181 agctttaaat ttataaaaag ttgatatata aagggaaatt atatattaat gtgtattaat
     6241 taatgaaaag atatgtagta taagagatag ttataaaatt atggtggttt ttagctaagt
     6301 aaagaaattt ttaataagga gaatttacac atgacctgtg gagttagatt ttgtgggggc
     6361 tgtaacccta gatacgaaag agggaaggct cttacaataa tcaaagagca cttcaatggt
     6421 agggtagatt ttagcatagc acaagagaac gtcgagtatg atttgctact tataattgga
     6481 ggatgcgcaa ctctatgcgc atcctatcaa caatataaag tgaaaaatga atgtgttaag
     6541 atgtgggatt ttagccatat agaaagagtt ataaatgtga ttgaatcagc aatttgtgaa
     6601 acttaaaaaa gctaaatggg gggatttcat tgagttggca agaattgtat caaagtaaat
     6661 tatgtagtgc tacagaagct gtaaaacaga ttaaaaacgg tgatactgta gtatttgcac
     6721 attgtgtagg tgaacctcct gcactagtag aggctatgat tgaaaatgct gaacaatata
     6781 aagatgttga gattaaacat atggtaagct tgggtagtgg tggatatact gctaagggaa
     6841 tggaagctca ttttagagta aatccaatgt ttgtaagtgg aaatgtaaga aaggcaattg
     6901 aaaatggaga tggtgatttt acacctgcat tcttccatga agtaccaaag ttgcttagag
     6961 aaaaaagatt aaaatgtgat gttgttttag cacaggtaac tccaccagat gaacatgggt
     7021 attgtagctt aggaacatca gttgattata cttatgaagc cattaaaact gctagaacag
     7081 taattgttca agtgaatgac cagtttccta gaacctatgg tgaggtagtc catgtatcag
     7141 agtttgacta tatagtggaa aaatcacaac ctttatttga actacaacct gcaaagattg
     7201 gagaagtaga agaagcaatt ggtaaaaatt gtgcttcatt aattgaagat ggttctactt
     7261 tacagctagg tattggtggg ataccagatg cagttatgtt atttttaact gataaaaagg
     7321 atttagggat tcattcagaa atgatttcag atgggacttt ggccctttat gaaaaaggtg
     7381 ttataaatgg taaatataaa aattttgata aagaaaaaat gacagttacc ttcttaatgg
     7441 gtactaaaaa attatatgac tttgcaaata ataaccctgc agtagaggta aaaccagtag
     7501 actatgtgaa tcatccagca attataatga aacaacataa gatggtttct ataaattctg
     7561 ctatacaagt tgatttaatg ggacaggtag ttgcagaggc tatgggactt agacaattta
     7621 gtggtgttgg aggtcaagtt gactttatac gtggagtgtc tatgggggaa gatggaaagg
     7681 caattatagc tatgccttca ataactacaa aaaaagatgg tacagtaatt tcaaaaatcg
     7741 tatctattgt ggatgaaggt gcacctataa cgacatcaag aaatgatgtt gactatattg
     7801 taacagaata cggtatagca gaattaaaag gaaaatctct tagagaaaga gcaagaaatt
     7861 taataaatat agctcatcca agtgtaagag aaagtctagc agtagaattt gaaaagagat
     7921 ttaaggagaa atattaataa tagaggggtg ttaataatgg aagcacttag agtagttcca
     7981 aagatatttt attttgatac atttaaagaa tttaatgaag aatttaaaat aggaaaaaat
     8041 gatttagtaa ttactaatga gtttatatat gagccatata tgaaacctct tggaatagat
     8101 acaaatttaa tttttcaaga aaagtttgga acaggtgaac catctgatga aatgatagac
     8161 tccatgacaa aggaaatgaa gaaatacaat tttgatagaa ttattgcgtt tggaggagga
     8221 acaatagttg atatatgtaa gatattagca cttgatgttc cagaaaagtc tattgattta
     8281 tttgaaggag aagtatcacc taaaaaagta aaagagttag tagtagttcc tacaacatgt
     8341 ggtacaggta gtgaagtaac aaatgtagct attgcagagt taaaatctaa acatactaaa
     8401 aaggggcttg cagtagaaga aacatatgca gactatgcag tgttaattcc agagacagta
     8461 aaagggttac cttacaaatt ctttgttaca agttcggtag atgctcttat acatgctatt
     8521 gagtcttatc tttctccaaa agcaagtcca tttacagaga tgtattctct acaagcaata
     8581 aaaatgatta tggatgggta taagaagata gttgataaag gagaagaaga gagatttaat
     8641 catcttagag actttgtact tgcatcaaat tatgcaggaa ttgcttttgg aaatgctggt
     8701 tgtgcagcag ttcatgcact atcttattca ataggtggag ctttccatgt tgcacatggt
     8761 gaagcaaatt atcagttctt tactgaagta tttaagatgt attctagaaa aaaacctaat
     8821 ggaaaaatta taaaatgtac aaaaatttta gcagatgccc ttgaatgtga ccctaactgt
     8881 gatgtttatg gagaattaga aaagttttta aataaattaa tagctaaaaa agctttgaga
     8941 gaatatggaa tggtggaaag tcagatagat gaatttacag atagtacaat agcaaatcaa
     9001 caacgactac ttgctaataa ttatgtagag cttagtagag aggaaataag agagatattt
     9061 gcaaatcttt attaatacaa ttttttattt atatgtatag tcaacataaa caatgctaat
     9121 tatatttatg tacaaataaa aataagggaa cttaaatttt aattaaagtt aagttctctt
     9181 atttttatat ggagttaaat ataagtatat ttttaattta aaatatgctt atatttaagt
     9241 ctattacttt atttgaaaca atttgtagaa tttcaaattc cttgacagta ataagtaagt
     9301 aattgtataa tcaaactgca atatattaat aatattagtg aaaatgaaag gattataaaa
     9361 tatgtataaa tcagaaaatt tttcaaaaaa atctgtatta ataaattcat ttttaagtaa
     9421 atttttaaaa ataattggat ggggtttggt aagcttattt acattatcag ccttagtact
     9481 ttcaactatt tccattataa ttggatgggc tgtaatactt cctattcaag tatgtgcagt
     9541 atttttactt ataggaggag tttgtatttt taaaggtaag agattaggag accaaatttc
     9601 tcgttataaa aaatattgta caattataaa caatagaaat attattccag tagaacttat
     9661 tgcagaaaac acatctaaat cattaaattt tataataaaa gatgtacaaa agatgataga
     9721 caaaaactac tttataaata cttatattga taaaagaaat aatcagattg tgttaacaaa
     9781 tgaagatttt attccaccaa gatatgaaga tgtagcatat gaagtcaaag aagaagaaaa
     9841 gactgatgaa tccaatgaag ttgatacaat tataaataaa ggaatgaatt atctaacaca
     9901 aataaaagaa gctaataaaa atattaaatc agaatcaatg ggcgataaaa ttgtacaagt
     9961 agaagatgtt acaagtaaaa tatttgatgt tgtaaaacat gacccatcaa aacttactca
    10021 aatacaaaaa tttatggatt attatcttcc aaccacttta aaactattaa attcatatca
    10081 tacattggaa gaacaaggaa ttgatagaga aaatataaca acaactatgg aaagtattga
    10141 aaatacaatg aatacgattg tagtagcttt tgaaaatcaa ttggactatc tgtttgaaga
    10201 tgaagccatt gatatttcta cagatattac tgttttagag aatatgttag tccaagaagg
    10261 attaacgagt ggtaaatttt aacttcaata gaaaaaatat tctgttattt ttaaacaatt
    10321 aattagtcat aaagtataaa atgtgtatta tataagttaa tcagtacttt atgaaggaag
    10381 aggagagaaa gatacaatga ataatttaga tgatatacca gttatgccaa ctttgacact
    10441 tgacccattt ggagaagaat caaacactaa tgatatagat aattctgact tattaatgaa
    10501 aaaggatgaa aaagacccag aagaagaaaa actgtctgaa tctgaacgca agatggtaaa
    10561 ggaatttgcg gaaaaaatag atattacaaa tacaaatatg attttgcaat atggagctgg
    10621 tgctcaaaaa aaggtagcaa gtttttctga aacagcttta aagagtgtaa aaacaagaga
    10681 tttaggagaa gttggagata tgcttacaaa tctagttact gatttaaaag cattttcagc
    10741 agatgaaaaa gaacaaagtg gttttttagg aatttttaaa aaggcaaata ataaaatttc
    10801 aaatttaaaa actaagtatg atagtgcaga ggtaaatgtg gataaagtaa gtaaagagct
    10861 tcaaaagcat caggttaaaa tattgaaaga tatagcaatg cttgataaga tgtatgaatt
    10921 gaacttagct tactcaaaag agcttactat gtatattata gcaggaaaac aaaaattaaa
    10981 ggatatgaaa gaatatgaaa tgccaaagtt gagagaaaaa gctcgtttat ctggttcaac
    11041 agaagatgct caatctgtaa atgatatggt ttcactttgt gacagatttg aaaagaaaat
    11101 tcatgactta gaattaacta gaatggtatc gcttcaaatg gctcctcaga taagattggt
    11161 tcaaaatagt aataatctga tggcagaaaa gattcaatca actatagtaa ataccattcc
    11221 attatggaaa aatcaaatag tgcttgctct tggaatttct cacttaaatc aagctatgaa
    11281 agcacagcgt gaagttagta atatgacaaa tgagctttta ttgaagaatg cagaaacttt
    11341 gaagatggga acaatagaaa cagcaaaaga atcagaaaga ggaattgtag atatagacac
    11401 aattaagaaa actaatcaat ctctaatatc tactattgat gaggtagtta aaatacaaca
    11461 tgatggtaga ataaagagac aagaagcaga agttgaatta tcaaaaatag aaaatgaact
    11521 taaaagtaag cttcttgaat ttacagttaa ataaaaatta tactaatata aaaagagact
    11581 gtctcaaaat agagataagt ctctttttca ttgtttaaat gattaaagta tatttatatt
    11641 ataaatttct attatctttt aacataacat catgagctcc accttcaact atactagtag
    11701 aagatacaag tgtaagttta gcattttttt gaagttcagg aatgctaagt gctccacagt
    11761 tacacatagt agaacgaact ttacttaaag aaagagttac attgtctttc aaagaaccag
    11821 cataaggcac ataagagtca acaccttctt caaaagaaag tttcttatct ccaccaaggt
    11881 catatctttg ccagtttcta gcacgagcag aaccttctcc ccaatactct ttcatataac
    11941 taccatttat attaactttg ttagttggac tctcatcaaa acgagagaag tatctaccaa
    12001 gcattataaa atctgcaccc atagctaaag ctaaagttat atgatggtca taaacgatac
    12061 caccatcaga gcaaattgga atataaatac ctgttttttc aaagtattcg tctctagctt
    12121 gagcaacttc aattatagaa gtagcttgtc cacgtcctat acctttttgt tcacgagtta
    12181 tacatataga accaccacca ataccaactt taacgaagtc agcaccagct tcagctaggt
    12241 aaaggaatcc ctcgcggtca actacatttc cagctcctac cttaactgta tcaccatatt
    12301 tttcacgaat gaaatcaagt gttatttttt gccactcaga aaaaccttct gaagaatcta
    12361 tacataaaac atcagcacca gcttcaacta aagcaggaac acgttcagca aagtctctag
    12421 tattaatacc agctccaact acatatctct tagaagaatc taaaagttca agtggatttt
    12481 ctttatgaga agagtaatct ttacggaata ccatatacat aagattacca ttatcatcaa
    12541 gtacaggaag agaattaagt ttgtggtccc atataatgtt gtttgcttcc tttaaagtaa
    12601 catctttgtt agcataaact atagatgaca taggagtcat aaattcacta actttagtat
    12661 ctaaatccat acgacttata cgataatcac gacttgcaac aatacccaat aatttaccag
    12721 ttgaagttcc atcttcagta acagctactg tagaatgtcc agttttttct tttaagtcaa
    12781 gtatgtcttt taatgtgtta tcaggtttaa tatttgaatc acttacaaca aaaccagctt
    12841 tgtgggattt aacacgtgct accatagcag cttcattttc aatagtttga gaaccgtata
    12901 taaatgaaat accaccttct ttagcaagtg caatagccat tttgtcatca gaaacagatt
    12961 gcataatagc agaagtcaaa ggtatattca tataaatatc tgcttcctcg ccctttttaa
    13021 atttagtaac aggtgttttt aaacttacat tagcaggtat acaatcagta gaagagaaac
    13081 ctggtacaag aaggtattca ctgaaagtat gtgatggtgt atcaaaataa aacgccattt
    13141 tttaatcact ccttatattt ttatactttt tataattgat agtattaatt ataacttatt
    13201 ctttaatttt attaaagtat tttgtcaaat attgagattt ttgaaaaatt taaactattt
    13261 taattaaatt tgtttaatat atattgcctt atagggtaaa gttgtatatt aaataatgtt
    13321 tagtgtttaa tagtagctaa tttaaaatta atctttagtg attcatataa ttacatttgt
    13381 atagtttata ttgataatat tactagagag tgcataaacc tcaaaaatac agataaatta
    13441 aatctatatt agtatatcca aaagtacatt taataaattt atttaactga attattattt
    13501 tcatttctat taaat
//
LOCUS       DAEQJM010000089        13395 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.090, whole genome shotgun sequence.
ACCESSION   DAEQJM010000089 DAEQJM010000000
VERSION     DAEQJM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13395
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.090"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            361..1062
                     /locus_tag="KRQ43_003249"
     CDS             361..1062
                     /locus_tag="KRQ43_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HBH2743589.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIINIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            1333..2151
                     /gene="larE"
                     /locus_tag="KRQ43_003250"
     CDS             1333..2151
                     /gene="larE"
                     /locus_tag="KRQ43_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HBH2743590.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNMDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKILGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLFNLGFSQFRVRM
                     HGEIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            2206..3354
                     /locus_tag="KRQ43_003251"
     CDS             2206..3354
                     /locus_tag="KRQ43_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBH2743591.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            3490..4878
                     /locus_tag="KRQ43_003252"
     CDS             3490..4878
                     /locus_tag="KRQ43_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743592.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYTTLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            4907..5605
                     /locus_tag="KRQ43_003253"
     CDS             4907..5605
                     /locus_tag="KRQ43_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743593.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     ENDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            5608..7041
                     /locus_tag="KRQ43_003254"
     CDS             5608..7041
                     /locus_tag="KRQ43_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2743594.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            7063..7800
                     /gene="truA"
                     /locus_tag="KRQ43_003255"
     CDS             7063..7800
                     /gene="truA"
                     /locus_tag="KRQ43_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH2743595.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    7911..8118
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8371..9570
                     /locus_tag="KRQ43_003256"
     CDS             8371..9570
                     /locus_tag="KRQ43_003256"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBH2743596.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            9817..10863
                     /locus_tag="KRQ43_003257"
     CDS             9817..10863
                     /locus_tag="KRQ43_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HBH2743597.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DGGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDERIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPSKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            10971..12134
                     /locus_tag="KRQ43_003258"
     CDS             10971..12134
                     /locus_tag="KRQ43_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2743598.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKIIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAQAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SKNPSSTDLQEIAKEITDISKKDYEIFSMYTGDDNWYYMIQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(12223..12603)
                     /locus_tag="KRQ43_003259"
     CDS             complement(12223..12603)
                     /locus_tag="KRQ43_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HBH2743599.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(12606..13265)
                     /locus_tag="KRQ43_003260"
     CDS             complement(12606..13265)
                     /locus_tag="KRQ43_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBH2743600.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
BASE COUNT         5396 a         1329 c         2290 g         4380 t
ORIGIN      
        1 atattaatta gcaaattcaa atcaaaaaaa ttcatatcaa caaatatatt acttcttatt
       61 acaaattata tcatatgttt tatattaaaa tattataata ttacaacgaa ttgttacaaa
      121 attacttatt attaaccatg aacatttgtt ttgtgctatc atatttatat aagggaattg
      181 tcataaaaaa tatcttgttc atacagtttt atatagaaaa aagaaatgaa tcttttcttt
      241 atataagtat attttgtaaa ttgcctctat atttatagtt taaataatag tggttttaaa
      301 aatctgacaa caaaaataaa actttcaaaa aattaaatct aaaaagaata ggagataaat
      361 atgagtattg aagatttata tgattttgaa tgtgttcctt tgaacaatga gattgatatt
      421 gatgttttat ttgaaaagat gatagaagat ggaaaagaaa aagaatatac accaattata
      481 gtcattgatg aaaaagtagg gctattaaga aaaaatatag atatgattac taaagagtat
      541 ggttctcttg aaaactatag agagtattgt ttaacaaaat ataatgaaat tgatgtaaat
      601 caattttttg attttaggaa gagtgagatt tcagaattat taaaggagct aattgattta
      661 gaagatgatt tttatgatta taaacatttt agaccaatta taaatataga tatatttcat
      721 gaatataaca aagtttacat agctaaaatt ccaacaatta aaccatatga agtatttgca
      781 tacataccta ttggaggatt taatgattgt cctagagatg aagaacatat agctattgca
      841 aaatattggt atgaaaagca tggaatcttt ccaatcgcaa ttggatgtga tacagttcaa
      901 tattctgtaa aaaatttaac taaagatggt aaaaaatttg atgacttatg tattgaatta
      961 gtattttatt gtgaggatat tattatacaa gggtatgaaa ccttaaaggc tcttaaggat
     1021 gtattaaaac gctctacaat agtgcttttt tggtgggatt gatattctat catttagata
     1081 gtattaaatt gttagtcacc aagaatccac ttactttagt tatggggagt gtgtcaaact
     1141 aggtttttat acacagtgta gcatagtaat atgtttaaat tacaaaggtt aaaaaaatac
     1201 tttaatattt ttaatattat aattaataga tttaaaggta attataattt ataaaataaa
     1261 tactttatat gttataatca ttaagaatgt aaaaaaataa tatatagttt tatagttcat
     1321 atttttccag atatggaggt aaattttgtg aaggaaaaag aaaaattaga taaattaaaa
     1381 aaaatgttac ttgaattagg cagtgttgta gttgcttatt ctggtggagt agatagtaat
     1441 tttttgctta aggtcgcaaa agatacatta ggtgaaaatg ttatagctgt gaccattcat
     1501 gcaatgatgc attcaagtag ggaaattgaa gaggctaaac aatatactca aaattttggc
     1561 gttaaacata tcatattaaa tatagaaaac tttgatttaa aagaatttaa agaaaatggt
     1621 gttgatagat gttatcattg taaaaaatat atattctcta aaataaaaga ggtagcaaaa
     1681 gaacataata taaagtacat agtagatggg acaaatatgg atgatttagg agactataga
     1741 cctgggctta aggcattgag tgaattagga gtgattagtc cattaaaaga tagtagttta
     1801 aaaaaagaag aaattaggtc gctttcaaaa atattaggat taaatacttt taataaacca
     1861 tcatttgcat gtcttgcaag taggattcct tatggagttg agataacaga tgaaaattta
     1921 agaatagtag aaaagagtga agaatatcta ttcaatttag gtttttctca atttagagtg
     1981 agaatgcatg gagagatagc tagaatagaa gttgggcagg aagaactagg taaatttttt
     2041 gaaaataaca attttaataa agttgatact aaattaaaaa tatttggctt taaatatgtt
     2101 acactagata tgtcaggata taaaatggga agtatgaatt taaatgtgta gattatttta
     2161 aaaataaata agttttatag ttaatataag gaaacaggag gttttatgaa aaattataca
     2221 ttaatatcgc catgtttttt tggaatggaa aaaatgctgg ctagagagat tactaattta
     2281 ggatatgaaa taataaaaac agaagatgga agaataacat ataaaactga tgagtttgga
     2341 atagcaaagt caaacatgtg gttgagatgt gctgaaagag tacatcttaa aattgctgaa
     2401 tttgaggcaa aaagctttga tgaattattt gaaaatacaa aaagaataaa ctggtctaga
     2461 tatatacctt atggagctca atttcctata tcaaaagctt cctctataaa atcaaaatta
     2521 tacagtacac cagatgtaca agccatagta aaaaaggcta tagtagaaag cttaaagaaa
     2581 agttatttag aggatggttt gcttaaagaa gataaggaga aataccctat ttttgtattt
     2641 atacacaaag ataaagtaac catttctata gatacaacag gagatgcttt gcataagaga
     2701 ggatatagag aaaaggcaaa taaagctcca ataagagaga ctttagctgc tgggcttatt
     2761 tatttaactc cctggaaagc aggtagagtt ttagtagacc ctatgtgtgg ttctggtact
     2821 atattgattg aagctgctat gattggtata aatatggcac ctggcttaaa tagagagttt
     2881 atatcagaaa agtggagaac tcttgataag aaaatatggt gggatgtaag aaaagatgct
     2941 tttaataaga tagataatga atctaaattt aagatttatg gatatgatat agatgaagaa
     3001 tctatagata tagctagaga aaatgctgaa atagcaggtg tagatgaata tatagagttt
     3061 aatgtaggag atgcaactca atttaaaagt gaagatgagt ttggatttat aatcactaat
     3121 cctccttacg gagaaagatt agaagataaa gacagtgtta aacagttgta taaggagctt
     3181 ggttatgcat ttagaaaatt aaaaaattgg tcgtattatt tgataacttc ttatgaagac
     3241 tttgaatatg agtttgggca aaaagcagac aaaaaaagaa aattgtataa tggtatgtta
     3301 aaaactaact ttttccaata tccgggtcct aagcctccta gaaataataa ataagtttta
     3361 catgatttat ttgtaaaata taaaatttta ttaaaataag taaaacatta tgatgccttg
     3421 aaacgtctaa ttattgtgag gagatttttg tgaacaaatt taaagattta taggattagg
     3481 aggagttaaa tgaaagtgtt aaagcttatt actgtagtag ccctgatgat gttatttgtt
     3541 actggatgta atataaaaac tgaatctcca gaacaattag cgaagatacc tgactatgat
     3601 gatacaaaaa aagtattgta tgatggtatt gaccagttac taaaaccaga ttcatctatg
     3661 atattgcctt ctaatacaaa agaagtagga aaaataaata aggtagattt aaacagcgat
     3721 ggaattgatg aattagtagt atttgaacaa aaagaagatt taagtaataa tgtgagtcag
     3781 gtagggtttg taaccttgag ttacaatgga gaaaaatacg tacttggaga ccatttttta
     3841 gaaaatggcg aatcaataga atatgctaat ttttatgatt tggactcaga tggatataag
     3901 gaagttatct tattggttaa atccaaagac aaaacgaata tgcatatata taaagtagta
     3961 gataatgaaa taacaaaaat atatgacttg gatgcatcat ggcttcaaaa taaagaagat
     4021 tttaatgaca tgaaagtaaa aattggatat atagatggag atgacaagtt agacatattg
     4081 atgcttcatt tgaataataa gactaatgaa atgtttgcaa gtgttgcaaa ttttgatggg
     4141 aaaatgaaaa tcaaagattc tgttaagttt gaaaatgtaa aaaacttaag tgaattatat
     4201 acaacattag gtaatgttgc ttcatctgtt ggaaattctt ctgcagctat aaaaggtatt
     4261 gtacttgata ttcctatatt gaaagataat aactatatta cgcagatact ttatatgaaa
     4321 gatgggaaaa ttaacaaagc ttttagtgat tatgataaaa ctattactaa atcttattat
     4381 atacctgtag atgatattga caaagataag attatagaaa tacctatagt tgcaggcagt
     4441 acaggtaata ataaaaatac ttatagttct aaatcatctg caactataag ttggtataga
     4501 tggaatggaa aagaaggtgc tgactcaagt ttaatattta caagtcagat atattataat
     4561 tataaatata attttaaatt atttattcca aataatttat ttgataaaat acttgttgaa
     4621 caggaatttg ttggagaaaa agcagtattt aaattttact attttgacta ttcagatcgt
     4681 aagaatttat ttaatatagt agtagagagt aaaaacaaac ttgaagatag aaaaaataca
     4741 ggtactcaaa actctattgt acttcaagag agcgatgaat atactttctt actagttgta
     4801 aacaatgcaa atgaaatgga taagctagat atgactatag acgcattaaa agaatatttc
     4861 tcattaatat atggttaata ttatactcaa ttggaggttt tattttatga aggaaaagat
     4921 acttatacta gaagatgaaa ttggtattag aagttttgtt agtataaact taaaaagaga
     4981 aggctatgaa atagttgagg caggtactgg aagagaagct atagaaaaaa tgacaacaga
     5041 aaatgatatt acaatagctc ttttagatgt gatgcttcca gatataagtg gtatagaagt
     5101 atgtaaattt ataagggaga attttgacca agtaggtata ataatgctta ctgctaaagc
     5161 tcaagaggat gataaaatag aaggatttat ttcaggagca gatgattaca tcataaaacc
     5221 atttagtata aaagagcttt tagtcagggt ttctgctctt cttagaagag tagcaaagga
     5281 tgattcaagt gttaagtcga gtgaaatagt ttctccacca tttatacttg atatagacaa
     5341 gagaaaatta tttaaaaatg gaaaggaaat tgagcttaca ccaactgaat tttcaatagt
     5401 gaaatatcta atatcaaatg ctaagcaatc gttaagtaga gaccagatat tagacgaagt
     5461 atggggaact aactatttat atgattttaa aatagtagat gtaaatataa gaaggataag
     5521 aaataaaata gaagatgacc catcaaagcc aaaatatata caaactattt ggggttatgg
     5581 atactgtttt agaaaggaag aataatagtg ttacattttg aaggtctgag aaaaaaagta
     5641 ataaaaaact attttataat aattattata atggttactc tgtttgaagg attgttcatg
     5701 ttttacatac aaaactacta ttatgattct gtcaaacaac tacttgaatc tgaaataaaa
     5761 tatgctgatg aatataatgc tattacaatg gaaactacaa gttttgagaa aaaagtaaaa
     5821 aatatatttg ataaacaacc attaactaaa aattcagaat ttggaatttc aataatagat
     5881 aaagataaaa atattatatt agaccaatat ggttttaaaa gtaaagaaaa agcaaactat
     5941 gaagatgtta acaatgcatt aaaagatata aaaactaaaa atttaacacc ttatacttat
     6001 agaataccag atacagggga gcatgttatg agtatctcct taccacttaa ggtaaataat
     6061 ataatagaag gtgttgttag atatacagta tcattagatg ctattgataa tgcaatatta
     6121 aagcaagcta catggcttat attagcagga atatttatac ttattatagc tatactaata
     6181 agtcttaaat ttgctgagac tcttataaaa ccattacgag agctaaagaa atttgcaaat
     6241 gaattggctg taggaaatta taatataaaa ttagaaaaga tgaagattgt agatgatgag
     6301 attggtgatt tagcacagac atttgaacac atggcacatg agattgacaa aagtgaaaaa
     6361 ttaaaagagg aatttatatc atctgtatct catgaactaa ggactcctct tacatctata
     6421 aaggggtgga gtgaaacctt aggttatgaa agtataacaa gagaagaact agacttaggt
     6481 ttaggcatta tacaagatga aacagaaaga cttataaaac tagttgaaga attattagac
     6541 ttttcaaggc tttcttcaga caggataaaa cttcatgttg atatagttga tgttgaaggt
     6601 ttaattgtag gtgttgtaaa tcaacttaaa gttaaagcag ctgaaaaaga tatatcactt
     6661 ttatttgaat ttgaaaatga atttatagag aacattcaag gagataaaaa tagattaaga
     6721 caggttctca taaatttaat acaaaattca tttaaattta cgagtcaagg tggttacata
     6781 aaagttgtag cttctcaaga tgaagagata acaaccatat cagtagagga taatggttca
     6841 ggtatagaaa agcaaaattt aaataaagtg ttagataaat ttttccaaga agattataat
     6901 aaggctggta gtggattagg attagcaatt agtaatgaaa ttgtaaaact tcatggtgga
     6961 agaatgaaaa tagaaagtga aaagaatgtt ggaacaaaaa taacttttaa tataaaaaat
     7021 aaatttgcta aacaagcata aattcttaga aagaggatta agatgagaaa cataaaaatg
     7081 atagtagcat acgatggttc aagatataaa ggatatcaaa aattaggtga caataatatg
     7141 actattcaag aaaaacttga aaatgtttta agtaaaatga ctaatgaaac agtggagata
     7201 atagggtctg gaagaactga tatgggagct catgcaagag gacaagtggt aaattttaga
     7261 actaattgta tggattcttt ggataaaatt caaaaatatt tatatgaata tttaccagaa
     7321 gatatagttg taaaaactgt tgaagaagtt gatgaaagat ttcattcaag atacaatgta
     7381 aaatcaaaga cttatatgta taaaattgac aataataagt atcacaatcc ttttataaga
     7441 aaatatgcta ctcatgtaag taaaaaatta gatttagata gaatgagaaa agcaagtgag
     7501 tatttagtag gagaacatga ttttactagt tttgcttctt ctaaatctaa gaaaaaatca
     7561 aatgtaagag aaatttattc tataaatata aaagaagatg ataatgttat agaaatatat
     7621 gtagaaggaa atggattttt gtacaacatg gtaaggataa tagtaggtgc tttgatagat
     7681 gttggtctaa aaagaagagc tccacaagat attaagtata tgcttgaatc aaaagataga
     7741 tgtcaatcat cagatactgc accagctaaa ggactatgtc tttggaaagt aacatattag
     7801 tcaattatat aaaactctct ttaaaataaa aataaaataa attatatagt tgacataaat
     7861 ggaaaaataa actattatat attttataag agagatataa aactttatat ttaaatcctg
     7921 tgagaaagag agtaacttct atgtgtttta tagagagctg aggatggtgg aagctcagca
     7981 aataagtatt agtgaaaaga actttggagg atactaattg aatttagtat gttagtaggt
     8041 aatctcgcct taagagaaag agtggataag tttatcttat caattagagt ggtaacgcgg
     8101 atatatttcg tctcttggtt tttccaagag gcgtttttta atatatttaa ttattagtgt
     8161 ttatctggta tgttgaacat ttactaattg attagctaag tttatcaata agagtggtac
     8221 cgcggatatt tcgcctctta gtattttaaa atactaaggg gtttttttag tattaaaatg
     8281 attttatgtg agtctaaatt ctcagagtca ttcaatatta agaatttcta taaaataaaa
     8341 attataattt aagattggga ggaattaaaa atgaaggaaa aagtagtatt agcatattca
     8401 ggaggacttg acacatcaat cataatacct tggttaaagg aaaattatga agatatagat
     8461 gttatagctg tttgtggaaa tgtaggtcag gaagataaaa tggaagatgt atatgaaaaa
     8521 gctttacaaa gtggagcatc aaaggcatat gtggatgata taagtgaaga atttgtaact
     8581 gaaactatat ttaaagccgt aaaagcagag gctaaatatg aaggaaaata cttattagga
     8641 acttctttag caagacctat aatagctaaa aaattagttg aagttgctca taaagaaggt
     8701 gcaaaatata tatgccatgg atgtacagga aaaggtaatg accaagttag atttgaagct
     8761 acaattgcag ctcttgaccc gactataaaa gttattgcac cttggagaat ttgggatata
     8821 aaatcaagag aagatgctat agactatgct gaaaaacata atataaaggt aacagcaact
     8881 aaagctaaaa tatattcagt agatgctaac ctttggcatg tttcaacaga aggtggagat
     8941 atagagcacc tagaaaatga acataaaaaa gatgtttata aacaatgtgt agacccagaa
     9001 gatgcatgtg atgtagctga atatgtagaa gtttactttg aaaaaggtgt acctaaaaaa
     9061 gtaaatggcg aagaattatc tccagttgca ctgattcata agttaaatga gttgggttgt
     9121 aaacatggaa ttggtgttat agatatagtt gagaatagac ttgttggtat gaaatcaaga
     9181 ggtatatatg agactccagg aggaacaatc ctttatgaag cacataatat tttagaaagt
     9241 gctactttag acaaagatac attacatttc aaacaaatgg tatcttataa atacggagaa
     9301 cttatttaca atggactatg gtattgtaaa ttaagagaat ctatagatgc atttatggaa
     9361 caaactcaag ataatgttac aggaacagta aaagttaaac tttacaaagg aaatataaaa
     9421 cctgctggaa tatttactga aaatgctctt tatgatgaag gaatatcttc ttttggaaat
     9481 agtgaacttt atgaccacaa agatgcagaa ggatttatta atttattcac tttaccatta
     9541 aaaatcagag ctatgaaagc tggaaaataa taaaataaat tatttaagag tgtataaaaa
     9601 ctatttttag gtttttatat gctctttttt tatttgaatt tattaaatta tacagtaaat
     9661 agtataaaaa aatatattat agttccaaat gacttaataa tgtgaaaata taagacctaa
     9721 aatataaatt ttataaatac aatagttatt gactctctca ttgtaagagg gtttatactg
     9781 aatctaatga aaatttatag tgaggagata gattatatga gaaaaataat tgaaattaaa
     9841 catcattcac atgattatga gtgtatgtgg aatggtatag aagatttata tataaataaa
     9901 accggtgaat gccttccaaa cgattttttc tttttactgt caggttttgg ttcattttgt
     9961 tatatgaaaa caaataaagc tgatttgaaa agaatggtag ctttgggaga tggaaggaca
    10021 aaacagatgt ataaattttt agcaccaatt gttggatttg aatacaaaca tcatgagttt
    10081 aaaaagtatg agcaagcatt aaagaaagca aaatctgaaa ttgatggtgg atatccagtt
    10141 attttaggag ctttagatat gtattatcta ccatattata agaagctata tcataaagaa
    10201 cacattcctt ttcattatat attaatggta ggatatgatg atgaaagaat atatctgtat
    10261 gattgtggta gaacagaatt attacatctt tcttatgata aattacgtga aagcatgaat
    10321 tgcaattccc ctggattaag caaagaaaat actatttgca caataagaat gaatacttca
    10381 aagaataaat ataacattgc tagagaagct attgctataa agcgtgatat gtttttaaat
    10441 ccatctaaag gatttttggg atataaaggt tttgaaaagt ttattaaaga gttgccacag
    10501 tggaacactg aattggataa agatgattat gataagattt tgaccaatat ggttatgttt
    10561 tttggaacag taccaacaat tccaaatgca atcaaaggaa ttaaagaacc agatactgtt
    10621 caatttaaag gtggatttga taaaatgagt agaatgctca acagtattgg ggaggaatac
    10681 aaaaacgact cttttataca agtagctgat atttttgata aaactgctat tataattgag
    10741 aaaatatcca atattataat agattattta actcaaacat gtgatgatac agaacaactt
    10801 ccgttattgt tctctgaggt cttagagcat atgaaaacag gatatttaat cttggatgta
    10861 taaaaaatat attgttgacc ctaacattac gtaatagtgt aatatgaaaa tatagcttga
    10921 atatattagt aggtattgat ggctgtaaaa ttaaaatttg aggtgtggat atgagaacag
    10981 tgaaacaagt ttctgattta actggaataa gtgtgagggc attacattat tatgatgaga
    11041 taggtctttt aaaaccaaat aaaattacag atgcaggata tagactttat gatgatgaat
    11101 ctattaaaac tcttcaacaa attttatttt ttaaggagat tgatattcct ttaagagagg
    11161 ttaaggaaat aatgtcaagc caatattttg ataaggttga agctctaaaa aatcaaaaaa
    11221 aattacttat tttaaaacga aagagactgg atgaattgat agagcttata aatcaaactc
    11281 taagaggaga aggaaatatt gattttaaag agtttgatat gagcgagtat tttaatgttt
    11341 tagaagaatt taaaagagaa cataggaata agataattaa aatttatggt agtgtagaaa
    11401 aatacaatga atatatagaa agagttaagt ctaatgaaga gaaaattgct aaaatggcta
    11461 taaaacaata tggaactatt gagaagtttg cccaagctat aaaaacaaat tttagcagtg
    11521 atatattgaa tttaggagaa aaatttgata gatataaaaa tgattgttta aaagaaaaac
    11581 atccaaaatt aaaagaatta tatagaaagc ttgtagaaga tttaagtaag aatccttctt
    11641 caacagacct tcaagaaata gcaaaagaga taacagatat atctaaaaaa gattatgaaa
    11701 ttttctctat gtatactggt gatgacaact ggtattatat gattcaaaat tatctagtaa
    11761 atcctatgtg gatagaagaa gtagataaaa agtatggaag tggagcaggc aagtttattg
    11821 gacaagtact aaagacttat ctaagagata gaaaaccaaa gataaataca ttgtatgaaa
    11881 aacttgtaga agatttgagt agagattgtt cttcaaggga agttcaaagc attgttgaag
    11941 aaatagacaa tgaaatgaaa agaagtaatg aattttataa aatagacaat ggtgaaagat
    12001 actttgatta tatgtcagag ctttatttac aagattctaa ctatataaaa gtaactgata
    12061 agaattatgg tgatggtgca tctaagttta ttggagaagc ttttaagatt tattttgata
    12121 ataataattg ttgaaaattt ggaagtaaaa aatatgtaag ttttataaaa gcacaaaaat
    12181 aaggatgtag attagctcca tctatatcct tatttaaagt tattaaaata tatagtttac
    12241 atcaaactta acactttcaa taatatttcc caaatatgtt tttatacttt caacttcttc
    12301 taaagatttt aatttatttt cagtataaat tgctttgtcc agaatattaa accttaatcc
    12361 tatttcatca aagtactcat gatttaaaac tttgtaccaa tggttttttt ctttattcca
    12421 actcgtagat attgaatcag cttctttttg agctttttcc caatcttcat tttctataga
    12481 tttttctaaa acagatatat tgtctttata tccttctgta aaatcatata gtttattgtt
    12541 aacgtaaaat ccaaataata caaataagat agtccatagt ataacaaatg ttgtagattt
    12601 caatattaat cacccttttt attttgaata aatattttgt cattttcatc taaaacacaa
    12661 ataagaacat ctttaaaagt ttctatgtga ttagatttta aaatacccat taaccagtta
    12721 gtatcttttt gagctatgtc tagattttta tttattattc taccatccag tataagtggg
    12781 ataggtaaat gattaaaagc tcttggagga gtactattgt agcttgatgc tggtacaaca
    12841 cttagattac catcagtctc caaaatagca tattgtacat cttttaggtt gaagtatcct
    12901 tgaatcctaa gttgttctaa taattcatct atactaattc tttctttttt aagctcttta
    12961 tatacaattt ttcctttatc tattaataca gaaggtttac ctgataaaaa tgaacttaat
    13021 tttctgcttt ttaatgataa gaatgaaata agagtctgca tgattacaag accagatatt
    13081 gctgcaacac catttatgat tggtatatta ttattttcca ttgggacaga tgcaacttct
    13141 gcaattaata gtgttataac taaatcaaaa cagttcattt cagctatttc accttttccc
    13201 atgactctaa gtgcaattag cactgttatg tataatataa tacttcttat taatactact
    13261 gtcatatcta tcaattactc ctttaaaaaa tatttacact tagttagtat atcctatata
    13321 aaaaatttaa ttcaaagtat aaaaaacctt aaataattgg attcaactat ttaaggtttt
    13381 tttgataatt ttaat
//
LOCUS       DAEQJM010000090        13182 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.091, whole genome shotgun sequence.
ACCESSION   DAEQJM010000090 DAEQJM010000000
VERSION     DAEQJM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13182
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.091"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            336..1505
                     /locus_tag="KRQ43_003261"
     CDS             336..1505
                     /locus_tag="KRQ43_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743601.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            1886..6139
                     /locus_tag="KRQ43_003262"
     CDS             1886..6139
                     /locus_tag="KRQ43_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH2743602.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKISYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            6288..6782
                     /locus_tag="KRQ43_003263"
     CDS             6288..6782
                     /locus_tag="KRQ43_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH2743603.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSVYIGDEKFNNLKNECIKK
                     GIDIKISKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKNIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            6898..7275
                     /locus_tag="KRQ43_003264"
     CDS             6898..7275
                     /locus_tag="KRQ43_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBH2743604.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            7481..7921
                     /locus_tag="KRQ43_003265"
     CDS             7481..7921
                     /locus_tag="KRQ43_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HBH2743605.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
     gene            8552..9859
                     /locus_tag="KRQ43_003266"
     CDS             8552..9859
                     /locus_tag="KRQ43_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743606.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLVLDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQSKILTDEAFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    9945..10207
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10333..11136
                     /locus_tag="KRQ43_003267"
     CDS             10333..11136
                     /locus_tag="KRQ43_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH2743607.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINKTLKEMKKDGTFDKIYDKWFK"
     gene            11174..11785
                     /locus_tag="KRQ43_003268"
     CDS             11174..11785
                     /locus_tag="KRQ43_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH2743608.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            11817..12488
                     /locus_tag="KRQ43_003269"
     CDS             11817..12488
                     /locus_tag="KRQ43_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH2743609.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            12787..13149
                     /locus_tag="KRQ43_003270"
     CDS             12787..13149
                     /locus_tag="KRQ43_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBH2743610.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
BASE COUNT         5319 a         1262 c         2348 g         4253 t
ORIGIN      
        1 aaaaaagatt atgaaaaata ttgaaggaaa aattttttca taatcttttt tctttcatgc
       61 aaaaagatac aagttacaac ttatatttgc atattaggtc gttagagaag tatatatata
      121 tttagtaagg aatcatactt tttataaaat gaaagataag atgtcgaaaa cttgcataaa
      181 tctgaaaaat ttttattatt aaaatactga ttttcatttt aaaaatgata aaaaaatgac
      241 aaataaagtt gcaaatagta atacttataa gtataattaa aaaagagaaa aggttttgtt
      301 aaactttata acaaaaaaag aagggatgat tcaaaatgga gaagttaaca gacaggagac
      361 aggttaaggc agtaagcatg gaaaccttca ttttcctaat attactagta gttggttttg
      421 ggtatgttgg tagtattatg ggagcaggaa tgatgttcaa agtaataatg agtacagcac
      481 atgctttact attggagaca gttttcttaa ttatggctat ggcagttctt gcaggcgcat
      541 taagcgcact actttcagag tttggagtaa tagcgttaat taataaaatt ttcgctgtat
      601 ttatgaagcc tttatatgga ctacctggtg ctagtatagc aggagctata acaacttatt
      661 tatcagataa tccagctatt ataccttttg ctaaagataa aacattcaca cagtatttta
      721 aacaatacca agttccagca ttatgtaact taggaacagc ctttggtatg ggacttatct
      781 taacaacatt tatgatttct caaggtacag aatatgtact tccagcatta attggtaatt
      841 taggtgcaat tataggtagc gtcataagtg ttagaataat gttgacattt actaagaagt
      901 tttataaata caatccggaa gaagataaag caacaggaac attagagaaa aaggatgaat
      961 ttagagaaat cagagaagga aatgtatttc aaagagcttt agatgcaatt cttgaaggtg
     1021 gtaaaatggg ggtagatatg ggaatggcta taattcctgg agtcctagta gtatgtacat
     1081 tggtgatgtt attaactttt ggaccatcta cagaccctgt tacaggtcaa gaagtttata
     1141 caggagctgc atatgaagga ataaaattac ttccagttat tggagataaa cttggattta
     1201 tattagaacc attatttgga tttacatcac cagaggcaat agcattccct ataacttcat
     1261 tgggagctgt tggtgcagca atgtctctag ttccagagtt tataaagtca ggagctataa
     1321 ctcctaatga tatagcagta tttacagcta tgggtatgtg ttggagtgga tatttaagta
     1381 cacatattgg tatgatggat gcattaaatg ctagacagtt ggcaggtaaa gctattcttt
     1441 ctcatacaat aggtggttta tgtgcaggag cagcagctca ctttatattt acactcgtag
     1501 gataaacgta atcagctaag ataaaaaata atatacaaaa aaatggttgt tgatatgtaa
     1561 taagaattta catatcaaca accatttttt tctgactaaa gataatttat aatacataaa
     1621 cattaagtgg atattagact taagttatat ttatgtaaaa agtaacaaaa atctgtagaa
     1681 atttatgaca aaatttagta cactaactat atgttcttat ttaaaattta aggttagaat
     1741 taggaattac ctagtagagt aagctttgat taataaaaga atcataaaat aaaaatatta
     1801 gtcataaaga ttataaataa cttacttaaa ataaagccat agaacttaca aaaattaaaa
     1861 aagcatataa atatggaggg gtacaatgga tgaattattt catataggaa ttgatgtagg
     1921 ttctacaacg gtgaaggttg tggtacttaa taatagtaat aatatagttc ataaagaata
     1981 tagaagacat tattctgatg taaaaaaatc agttaaagaa gtactaaatg gtatatatga
     2041 aaaattggga gatataaata ctaccattat aataactggt tcaggtggaa ttggaatatc
     2101 aaaaaaatta ggtgtaaaat ttgttcagga agttatatct agtacaaaat caatagagta
     2161 ttttcatcct gaaactgatg ttgtcataga acttgggggt gaagatgcaa agataacata
     2221 tctaagtgga ggaatagacc aaagaatgaa tggaatatgt gcaggtggca ctggagcatt
     2281 catagaccaa atggcatcac ttttaaagac agatgccagt ggattaaatg aacttgctaa
     2341 agggtataat gttatatatc ctatagcttc aagatgtggt gtttttgcta aaacagatat
     2401 tcaacctctt ataaatgatg gagccaatca gactgatata gcaatgagta ttttcaatgc
     2461 agttgtcgta caaactgtga gtgtcctttc ttgtggaaga aaaatagaag gaaatgttgc
     2521 gtttttgggt ggtccattgt actttttatc tgaacttaga gaagcattta aaagagtatt
     2581 ggatttaaaa gatgaaaaca taatcttccc agaaaatgca caactttata ttgctattgg
     2641 agcaggatta ttatcagtag atgaagataa tatacaacta aaatctctaa tagaaaaatt
     2701 ggatagtata aagaatattg aagatggaga agtaaattta ttagaacctt tatttaaaga
     2761 taaaaatgag tatgaagaat tttcaagaag acatgaaaaa gaaaaaataa gttatgtgga
     2821 cataaattca ataaaaagca attgttattt aggaattgat gcaggctcaa ctacaactaa
     2881 agcagcactt attgatgagg atggaagact tgtatattct tattataata gcaatgaagg
     2941 aaatccatta aaaacaacca ttaaagttat aaatgaagta tatgatatat taccaaaaaa
     3001 tattaaaata ttgagttcaa ctgtaactgg atatggagaa ggtcttatta aaaaagctct
     3061 taaaatcgat aacggagaga tagagactat agcacattac aaagctgcta aatttttcaa
     3121 taaagatgta gattttatac ttgatattgg tggtcaagat atgaagtgcc taaaaataaa
     3181 agatggagta attgataata taatattaaa tgaggcttgt tcatcaggtt gtggctcatt
     3241 tttagagaca tttgcaagtt ctttatctat gacaatagaa gaatttgcac atgaaggtat
     3301 ttattctcaa aatcctgtag atttaggttc aagatgtact gtatttatga attctagagt
     3361 aaaacaagct caaaaagaag gtgcaagtgt tggagatata tcagcagggc tatcttattc
     3421 agtaataaaa aatgctttat ttaaagtaat aaagattaga gatttaaatg agattggtaa
     3481 taatattgtt gtacaaggtg gaacctttta taatgatttg gtgcttagaa gctttgaaaa
     3541 actaattgga aaaaatgtaa ttagacctaa tatttcagga attatgggag cttttggttc
     3601 agcacttata gctaaagaaa aatatgaaag tggatacaaa acatccttgt tatctaagga
     3661 agagttgaat aatatcaagc tagaagcaag tgtaactaga tgtaaaggtt gttcaaatca
     3721 ttgtcttctt acaataaata aattttctga taatgaaatt tttatttcag gtaatagatg
     3781 tgagaagggt gaagctattt atggtgataa aaaaatagga ttagaaaaga aaaaaccaat
     3841 aaatttattt aagtacaaat acaatagaat ttttagatac aaaccattgg aaaaagaaga
     3901 agcaaaaaat ggggaaatag ggataccaag agtattaaat atgtatgaag attatccatt
     3961 ttggtttact tttttcaatg ctatgggctt tagagttgta ctttcagata ggtcatcaaa
     4021 acagttatat gaaactggta taactagtat tgcatctgaa acagtttgtt atccaggaaa
     4081 attagttcat ggacatatag aaaatttaat tgcaaaaggt ataaaaaata tattttatcc
     4141 aagtgtaaca aatgaaaata aagaggattc aaatgcagat aattattata attgtcctgt
     4201 tgtaatatca tattctgaag taataaaaaa caatgtagag aatataagaa ataagaacat
     4261 aaattatata aatccattta taagtctaaa tgataaggaa aaattgaaga aaagactata
     4321 tgatgaatta tcaagacatt tttctgatat aaaaataact aaagaagaag ttaatcatgc
     4381 agttgataaa gctactgatg aacagaattt atttaaaatg gagatacaag cagcaggtga
     4441 aagagcactt aaagaaataa aagaaagaaa tatgaagggg attgtgttat gtggaagacc
     4501 atatcatata gacccagaaa taaatcatgg aatgccagag cttataaatt cattagatat
     4561 ggcagtgctt actgaagact ctatatgtca tttagccaat gtacaaagac cacttagagt
     4621 tgtagaccaa tgggtatatc attcaagatt gtataaagca gctagttttg taagagataa
     4681 aaactatttg gaacttgttc aacttaattc atttggctgt ggattagatg cagtaactac
     4741 agaccaggtt caagaaatac ttaatgaaaa atcgaagata tatactatta taaagattga
     4801 cgaaggcaac aatttaggag cagctaagat aaggatgagg tccttaaaag cagctatgtt
     4861 tgagagagaa agcaaaaata tagatgtaaa aaatataaag gtaaacagga tacagtatgc
     4921 taaaaataat cagataacga acaaacatac tatattagca ccacaaatgt ctccaataca
     4981 tttccaattc cttgaaaaag ctgttaactt aagtggttat aatatagaaa ttctaaaaga
     5041 tactgatagt agtgtaattg aagaagggtt aagatatgta aataatgatg catgttatcc
     5101 agctataata gttgtaggtc agctaataac agcattaaaa tctggcaaat atgatttaaa
     5161 taatacttct gttactataa ctcagactgg tggaggttgt agagctacaa attatattgg
     5221 attcttaaga aaggctatat atgatgctgg atttaaagat gttcctgtca ttgcacttag
     5281 tgtaaatgga atagaagata gtggtataat ggataatata tcactaaaat taatcaatag
     5341 actctttatg tctgttgttt atggtgattt gctgatgaaa gtactatata gagtaagacc
     5401 atatgaaaaa gttactggaa gtgcaaatgc tctatatgaa aaatgggttg atatatgcaa
     5461 atcttctctt gttaaagcaa aaatttctgt atttactaga aatataaaag atatagtaaa
     5521 agaatttgat aatttagaga tactagatat caaaaaacca aaagtaggtt tggttggaga
     5581 aatattggtg aaattccatc caattgcaaa taataattta gtagatatat tagagcgaga
     5641 aggtgctgaa gcagtcgtgc cagaccttac aaatttcttc ttaagttgtg cctttaatac
     5701 tatatacaaa cacactcatt tagaaggaag tagaaagagt agaatgatag gagaagcatt
     5761 tatatacata actggaatat atcaaagagt atataaaaaa gcacttgata agagtgagag
     5821 attttatgct ccagccaata taaaaaatgt tgctaaaagt acagaaccag tagtgtcatt
     5881 aggtaatcaa actggagaag gttggctttt aacaggtgag atggttgaat tattaaatga
     5941 aggtgtagaa aacattattt gtatgcaacc ttttggatgt ttacctaatc acataattgg
     6001 taagggttct ataaaagaat taaagaggtt gtataaaaat gcaaatataa tacctattga
     6061 ttatgaccct tctgcaagtg aggtaaatca acttaacagg ataaaactta tgctttctaa
     6121 ggcttttaaa aatatataag atttatattt tgatatgtta aaagttaatg aatttaaaaa
     6181 tatactctat attaagtatc tataaaaaag agttatccta ttttttaggg taactcttta
     6241 ttagttaaaa aattatatgt atactgatat taaagggggg aagtaatatg agtttagtat
     6301 atgatgttta taaatcaaaa ttaggaaatt tgtacatatt aagtgaagat ggttttatag
     6361 ttagtgtata cataggagat gaaaaattta ataatttaaa aaatgaatgt attaaaaaag
     6421 gaattgatat aaagataagt aaggaagatt taaaggaagc aataagccag atagatgatt
     6481 actttaatgg aaaaagaaaa gtctttaatt taaatattcg tattgaaggg actgaatttc
     6541 aaaaatcagt ttatagggaa atgttaaaaa taccttatgg agaaacattg tgttattcag
     6601 atatagcaag aaatataaac aatccaaaat cagtaagagc aataggacaa gcaagtaaaa
     6661 gtaataaaat tccaataata ataccttgtc atagagtagt tggcaaaaaa aatattggtg
     6721 gatatatggg gaatcattct gatttgaaag agatactatt aaatttagaa agacagagtt
     6781 aacttagaaa gaaatgtttt tattgttaat atttgatata ataatagtaa aaagaagtat
     6841 tttttacaaa aacaatgaag aatttatttt aatttacaaa aatgaggggg aattttaatg
     6901 tgtgataaag ttatagcatc aaaatatcat gagaagggat ttaattgtgc agaatcagtt
     6961 ataaaagcat ataatgagga atttaataca gatataccag tttgtttagg aagtggactg
     7021 ggttcagggt gtggggttgc tagtttatgt ggtgcagtaa atgcatcaaa tataataatt
     7081 ggatacgtaa aaggcagaaa ccacgaagat gaaagtacta aagctaaagt atatgctaaa
     7141 gatttaacta caacagtaag aaaagagtat ggttcagagt tatgtataga cctaaaaaaa
     7201 gatttagttg cttgtagaga aataatggat ttcgcatatg atagtctaaa ggaaacttta
     7261 aaaaaagaat tataagaaaa taagctatca agtataaatt atttgatagc ttatttttat
     7321 agtcgatact aaataaatca aatatatttt agaattatta tttgtaaata aacagcaaat
     7381 aattttagga tttttattta atatagtttt tatttatatt tatttttgaa tatgttatac
     7441 tttgtttaaa taaatatttg taatgaggga gatgagaaga ttgaagaatc tcaatttact
     7501 tattaataaa ttatattcaa aaaatcataa tgaagcatat aaaacttttt tattcttaga
     7561 aaatgaaagt ttaaaatcaa atattacata ttgttttttt gactcattcc tagaaatgat
     7621 tgataacgaa aactcatata ttcgaacaag gggattgtta ttaatctctg caaatgctca
     7681 gtgggatatt gataataaaa ttgaaataaa tatagatagt atactaagtc atatcgtaga
     7741 taaaaaacct tctgtatcaa gaatgtttat taaatccata cctaatatta caaagtataa
     7801 agaaaatctt attaatcgca taaaaatgga attaagtaat gcagatataa gtatttataa
     7861 taataatatg aaaccattag tagaaaagga tataaacgat acattatcta atattagtta
     7921 aatattaata tagaaattga atattatcta gttacaatta tttataacta agataataaa
     7981 acaacaatgg tgctaattta tatgtataaa ttaattatga aaaatttata taagtaaaat
     8041 atattaacat aaaggtaaaa ttttgtatac taaaagggaa tatttacagt ttaatggcag
     8101 ttttaaaata ataaattaaa gctgtcattt ttatttaaaa atttttagaa aaagtacaat
     8161 agtgttaatg tgtgaattag ataaggtgta tataataatt tagatgatat gatataaaat
     8221 atgttgtaaa ttaaatgttt tctttgacaa tatatacaca aggatgataa tatctatatg
     8281 aataaaagat agtgtgtaat ttgataatat gtaattataa cattatgata taattacaat
     8341 aaagtatgta ataatctgta gaaatttcaa gctagttatc taagttttcg gataactaaa
     8401 tctaaacgga atacataatg tattaaataa atgatgatac taaaatgata ctatttttat
     8461 agaaatttat tgaggtatat aattgatgaa aataatatat taaattatat aatatattga
     8521 gttttacata aaagcgaagg tgggaataaa aatgaaagaa attgctgatg ctataacatc
     8581 agagtattta agctatggta tcaatgaaga tattagtatc tatgaaggta gattttgcat
     8641 atatttagat aaaaaatata gatgtaatgg gaaaatttat tataaaatga cacctccaat
     8701 atctataagt tttaaagcag acataggttg tgttgaagag atagacaatg aagatgacaa
     8761 tttagttttg gattatgata atgctattct tgaagttcat ggatacaaaa ttatttctat
     8821 aacaataaat actttaagtg aatttagtgt agaaggttat atcaatgatg actgcataaa
     8881 atctaagaac tcctatgttg aatatgtaga ttttaatata ataaacttag ataaaatacc
     8941 tggaaaacta attaaataca atgataaggt atacgcaggt agaattgaat ttgatataaa
     9001 tgattatgtt gtaactatag acaagcgata tgattataga aaagaattaa aatcagaatt
     9061 aaagtctaaa tctggagcaa taataactca tataggtagg attagaagaa aagatggtag
     9121 aatttttaga acaaataata caataaatct tttagataga atatcaacag ctttgagttt
     9181 tatgtgtgga agatatgtag ggttttgttt ggccaaaggg tatagaagtg gtaatgaagt
     9241 ttatagaata tggaatgaaa atcaaatatc tccttttaga tatgtaccaa catggtcaga
     9301 tacactttca aattatcata atatggaaaa atatataagc cttatgtgta aaaagctaga
     9361 agatttttat tatggttctg ctataaagag tgttgttgat tggtacatag aatctcttgg
     9421 aagtgctacc atggaaaaca atataatatc tgtacaaatt gcacttgaaa ctttgtcata
     9481 tgtaattcta gtggaacaaa gtaagatact tacagatgaa gcatttgact gtaatttggc
     9541 atctaaaaat ataagactct tacttgatac atgtaagata ccatatggta aacatgaatt
     9601 aaatatattt gataatataa taaaaaataa atttgatgat ggagtggatt tagttattta
     9661 tttaagaaat agcatagttc atccaagtag aaagactcat agagctgtgt tagaggttga
     9721 agatatttgg aatataattt caataggaac gagatatatt gaacttgttt tactctttat
     9781 tttaggttat agaggagaat attcaaacag attagtagaa aggtgttatg gtgaagtgga
     9841 agttgtacct tggaactaga tttttatatt tattttaaaa tatatattga catatattgc
     9901 cttatgctat aaaatcaata tcataataat aattcagaat aacattaaat gctaagaaaa
     9961 gaaatagtaa aggtagttaa tcttaaacag agagtttccg attggtgaga ggagcaatag
    10021 attttacttt gaacacatct ttgagcagga ctctgaaaga gtagaaatac tttattagga
    10081 gatttccgga atccttgcac ccgttatagt gctagagtat aataatttta ttgtacttaa
    10141 agaggttagt gtcgtgaggc attaatgaac agaggtggaa ccacgagagt taactcccgt
    10201 cctctagcag aagctagagg cgggagtttt ttaatataat tttttaagcg cgcagagaat
    10261 tatattgcaa tagatacact ttttaaaaaa taatcaaaat attttaaaaa ttaaaaggcg
    10321 agggagaata ttatgaaaaa tatattaaaa aaagtaggaa tatttacaat tatgttaggt
    10381 ttattaggtg gagttgtagg ttgttcaaaa ccagataatg aaaaagataa ggatgcttca
    10441 aaggaatcta aaaaagaagt agttgtaggg tttgataata cgtttgtacc aatgggattt
    10501 ttagatgaaa agggagatac agtaggattt gacgtagact tagctaaaga aacatttaaa
    10561 agacttggaa tggaagttaa gtttcagcct atagattggt caatgaagga aactgaatta
    10621 aatgattcaa aaactgtaga tgtattatgg aatggatatt ctataacaga cgaaagaaag
    10681 aaaatagtat catatacaga accatattta caaaataaac agataatagt tactctaagt
    10741 gattcaaaaa taaattcaaa agctgattta aaagataaag aagttggaac acaacaaggt
    10801 tcaacagcac ttgatgcagt ggaaaaggat aaagatttta tgaatagctt aaaaggtgga
    10861 gcaccagttc tttatgatac ttatgataaa gcacttagag atttagagat aggtagaact
    10921 agtgcagttg ttggtgatga agttttaatt agatattata tgggacaaaa gggtgaagac
    10981 aaatacaagg tattaaaaga cgattttgga ttagaagatt atgttgtagc aacttctaaa
    11041 gaaaatccag aactttgtga gaaaataaat aaaacattaa aagaaatgaa aaaagatgga
    11101 acttttgaca aaatttatga taagtggttt aaatagaaga taagttagct gttaagaagg
    11161 gggcactaaa ggcatgttac aaggtttaga gatagttata gcaatgtttt gtataacatt
    11221 gatagtatca attccattgg ggattggagt tgcattttta agattatcaa agaataaatt
    11281 agtaagtggt attacacaat gttatatatt gataatgaga ggtacacctt tacttttgca
    11341 aatgatagtc atattttacg gattacctct tttaggaatt gtatttgaca gatttacagc
    11401 tggagtagta gctttcttct taaattatgc agcatatttt gcagaaatat ttagaggtgg
    11461 aatacagtca atcgatagag gacaatatga agcttcaaaa gtactaggat ttgataaatt
    11521 tactatgtat aagagagtaa tctttccaca agtttttaaa agaatactag cacctatttc
    11581 aaatgaagta atcacattag taaaagatac atctttagta tatatattag gattaaatga
    11641 tattttaaga atatctcaaa tagcaatgaa cagggaagca agtctgttac cattatttga
    11701 ggcaggagcg atatatctta tatttgtagc tatacttact aagggatttg aattacttga
    11761 aaaaaaatat tcttattata gataaagtta caatattata ggaggaggtt ttttatatgt
    11821 tgaaaatcaa aaacttaaat aaatcattta aaaaaaatag agtacttaaa gatatttctt
    11881 ttgagttaga agaaggtcag attggagttt tacttggtaa gtctggtgca ggaaagacca
    11941 caatattaag atgtataaat ggtcttgaag aatttgatag tggagagatt ataatagata
    12001 atgaggtaat aaaaaataag agagatatgg caaaaatacg aggaaaaata ggtatggttt
    12061 ttcaaaattt caacttattt cctcatatga cagtccttga aaatataatt gaatccccag
    12121 ttaatgtttt taaagttcct agaaaagagg ctgaagagag ggctagagaa cttttaagat
    12181 tagttgattt agaagataaa ttaaattctt atccatttga attgtcagga ggacagcaac
    12241 agagagttgc tatagctagg tcatgtgcat tgatgccaaa agtcctttgt tttgatgaac
    12301 ctacttctgc acttgatatt gatactattc aaagagtagt caatataatg aatagactta
    12361 aagacaaagg tatgacaata ttaataatta cacatgatgt tgtcttctca aataatgttg
    12421 cagataaaat tataagtata aaagatggta tagtagaaaa tgttcaaata aaagaaaaaa
    12481 ttgtttagag ttttataaat ataaactagg gtagaatttt ataatataaa taaagggcaa
    12541 gtaaaatcaa atatactatg cccttttgtt atctcaaaat ttaatcttat attttatgtt
    12601 taagttacat tataatttat aataaaaata aaaggactat ttaaatatat aatgtgaata
    12661 aatgtttaat aatttgaaat atgataattt tttatgttga aagcttataa tgattatgat
    12721 ataaattggt tatagtatac aatttatggg tataacaata aaaaattaga aaggaatttt
    12781 tataaaatga ttaaattata tggatataca aaatgctcta ctgttaaaaa agctaaaaat
    12841 tggcttaagg aaaataattt agaatttgaa gatatagata tggttcaaaa ccctcctagt
    12901 aaagaggagt taaaatcaat ttataagact agtggatatg atataaagaa attttttaat
    12961 acaagtggta tgaaatatag agaattgggt cttaaagata ttgtaaaaac tgaatctgat
    13021 gataaacttt tagaaatatt ggtaagtgat ggtatgctta ttaaaagacc attacttttg
    13081 gatggtaaaa atgtattatt gggctttaaa gaagatgtat ggaaaagtac tttgctaaaa
    13141 gaagattagg aagagatagg tgtgttgatt aaaattatta at
//
LOCUS       DAEQJM010000091        12979 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.092, whole genome shotgun sequence.
ACCESSION   DAEQJM010000091 DAEQJM010000000
VERSION     DAEQJM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.092"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            136..2448
                     /locus_tag="KRQ43_003271"
     CDS             136..2448
                     /locus_tag="KRQ43_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH2743611.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKENNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDTTSNKVNYISDELD
                     TTSNKVNYVSDELDTTSNKVNYVSDELGMALHKVNCVSDELDMTSNKVNYVLDELDIT
                     SNKTDYISNELYNLSNKSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIKFKVCF
                     DMFMTDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFFME
                     LAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNLVAWEDKKFET
                     PSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMDKK
                     SIAQAYINQRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHG
                     NPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            2536..2871
                     /gene="spoIIAA"
                     /locus_tag="KRQ43_003272"
     CDS             2536..2871
                     /gene="spoIIAA"
                     /locus_tag="KRQ43_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HBH2743612.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            2885..3313
                     /locus_tag="KRQ43_003273"
     CDS             2885..3313
                     /locus_tag="KRQ43_003273"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HBH2743613.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            3336..4100
                     /gene="sigF"
                     /locus_tag="KRQ43_003274"
     CDS             3336..4100
                     /gene="sigF"
                     /locus_tag="KRQ43_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HBH2743614.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            4380..4817
                     /gene="spoVAC"
                     /locus_tag="KRQ43_003275"
     CDS             4380..4817
                     /gene="spoVAC"
                     /locus_tag="KRQ43_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HBH2743615.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            4971..5984
                     /gene="spoVAD"
                     /locus_tag="KRQ43_003276"
     CDS             4971..5984
                     /gene="spoVAD"
                     /locus_tag="KRQ43_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HBH2743616.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            5998..6360
                     /gene="spoVAE"
                     /locus_tag="KRQ43_003277"
     CDS             5998..6360
                     /gene="spoVAE"
                     /locus_tag="KRQ43_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HBH2743617.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            6543..7559
                     /locus_tag="KRQ43_003278"
     CDS             6543..7559
                     /locus_tag="KRQ43_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH2743618.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFVGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDRSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            7934..8776
                     /locus_tag="KRQ43_003279"
     CDS             7934..8776
                     /locus_tag="KRQ43_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH2743619.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            8791..9255
                     /locus_tag="KRQ43_003280"
     CDS             8791..9255
                     /locus_tag="KRQ43_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743620.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIITCFGQMIALKTQAQDLLIGSISG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            9242..10414
                     /locus_tag="KRQ43_003281"
     CDS             9242..10414
                     /locus_tag="KRQ43_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH2743621.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGKVALIKAIKVLAMCGVDILYSK"
     gene            10458..11393
                     /locus_tag="KRQ43_003282"
     CDS             10458..11393
                     /locus_tag="KRQ43_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HBH2743622.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(12192..12590)
                     /locus_tag="KRQ43_003283"
     CDS             complement(12192..12590)
                     /locus_tag="KRQ43_003283"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBH2743623.1"
                     /translation="MKWKELYNNARGKLNPRTISPFIDAGGVAAAILTDSGNVYTGVC
                     IDTACTLGMCAERNAIANMITNGESKITKLVCVMSNGSVGSPCGACREYLMQLDKDSA
                     CIEILVNVETEKTVKLSELLPDWWGSDRFI"
BASE COUNT         4948 a         1548 c         2416 g         4067 t
ORIGIN      
        1 ctgtgacttt agtcatggga ggttcagaaa atatagctat gttttatata ctgtagtttt
       61 gaacatagaa agtttaataa attatagtat atattaattt ttaataaggt aagaaagtag
      121 aaagaaggat attttatgga tataataaaa aaattaagtc atggatgtac attagattgt
      181 catgattgtt gtaaattcaa tgtttatact aaagaaaata atgtagtaaa aattgaagga
      241 gataaaaatc atccttatac aaaaggtttt atatgcaaaa aagggatggc tcatttagat
      301 agattaaatc ataaagatag aataaagact cctatgctta aagttgatgg agtatggaaa
      361 gagatttctt ttgataaggc tatagaaata atggcagaaa agcttacata ctataaagaa
      421 aagtatacat caaagtctgt catgcattat gaccaatatg gaagtgggtc tgtgctaaaa
      481 tacataggag atatattttt taatttttat ggaggtgtta gcagacataa gggtggtccc
      541 tgttggagtg cagggatgca tgctcaaaaa tatgattttg gagtagctaa gagtcatgct
      601 atagaagata tgttaaatag taaaagtata tttgtgtggg gaaaaaatcc agcatatact
      661 acaattcata ctatgcaaat aattaaaaaa gctaaagaaa aagggataaa gatagtagtg
      721 attgacccca tatatacaaa aacagctcaa atagcagata agtatgtaca ggtaaatcct
      781 ggaacagatg gagctttagc tatagctatg gcaaaaatta tagtagaaga taaattatat
      841 gatgaagaat atataaactc gtatgttatt ggttttgaag aatataaaaa atatttatct
      901 tcattggaat taagtttttt aattgatgaa tgtggtgtta aagagaatga tataagagag
      961 ttagtggatt tatatactaa caaatattca agtataaatg ttggatatgg gcttcaaaaa
     1021 tataaaaatg gtggaaacac aataagagcg atagatgctt taggtgctat aactggtcaa
     1081 ataggattta gtggtggagg ggtaaactat gctaataaag tttatccaag tgttataaat
     1141 tctgaccctt acaatagcca atcatatggt gaagataggg agttttatgt aagtaatatc
     1201 agtaaattta tagaagaatc tttaaaaaat acatcaaata aagtaaatta tgcatcagat
     1261 gaacttgata caacatcaaa taaagtaaat tacatatcag atgaacttga tacaacatca
     1321 aataaagtaa attatgtatc agatgaactt gatacaacat caaataaagt aaactatgta
     1381 tcagatgaac ttggtatggc attacataaa gtaaattgtg tatcagatga acttgatatg
     1441 acatcaaata aagtaaatta tgtattagat gaacttgata taacatcaaa taaaacagat
     1501 tatatatcaa atgaattgta taatttatct aataagtcaa tcaaagataa tattcctata
     1561 aagatggctg tgataactaa aagtaatatg ctgaatcaac tgccagattt agtagaattg
     1621 gagagggtgt tttcaaaaat taaatttaaa gtatgttttg atatgtttat gactgataca
     1681 gctactttat gtgacatgtt tataccgtgt acaaatacac tagagagtga agatataatt
     1741 tatagctcaa tgaccaatcc atatataacc tataatgaaa gagctgtaaa gccagcacat
     1801 aaattgatgg atgaatatta tttctttatg gagctagcta aaaaaatggg attaaatgat
     1861 tatccttttg tagaaaagag aacttattta gaaaaagtga ttgaaccact taagcgtttt
     1921 gacaaaaatc tggatataga aaaacttaaa aacaattact ttactataca taaccttgtt
     1981 gcttgggaag ataagaagtt tgagactcca tctggaaaat acgagcttta ttcagaaagt
     2041 ataaaaaact tgggaataag tccaacacct gtatatataa gcaataaata taaagaaata
     2101 gaagataaaa atatttcttt tagattatta actaatcatc atgcagatac tttatttagt
     2161 cagcatttta tggacaaaaa atctatagct caagcatata taaatcagag aatggctaaa
     2221 aaagtaggta ttgaggacaa agatattgtg atattgaggt caaaaaaggc aaaaataaat
     2281 gtacaaataa atatagatga tggagtaggt aattatatag taaaaatgta tgttggttgg
     2341 tggaagaaac atggaaatcc taatagttta acagacactg gtatatcaga ttttggaggt
     2401 caggtaacat ataatgaaag tatggtagaa ataatacgac aaaactagtt aaatttcatt
     2461 gaaggaataa aaatataatt atagaattga ttaaaagtta ctatttttac aaaactattg
     2521 aaggagggat ttttgatggt aaattattcc ttagaacata agaatctata catagaattt
     2581 atgtgctcag aactagacca ccatgtagcc aatgaaataa gggaagaaat agataactta
     2641 ttaagtgtaa atcaagtaaa aaatgttgta tttaattttg aaaatattaa ttttatggat
     2701 tcttcaggta taggcgtcat cataggtaga tataaaaaga tttctaatga agggggacga
     2761 gtttcagtaa ttaatataag ttcacgagtt aagaagattt ttgatttatc tgggttaaat
     2821 aaaattattg gcatttatga tacgtatgaa gaagctctaa gttctttgta gggaggagta
     2881 tgtgatgaat aatattatgg aagttaaatt ttcggcaata tctgaaaatg aaagtttagc
     2941 aagagttata gtagcatcct ttgcagctaa gttagaccca acagtagatg agttagtaga
     3001 tataaaaact gctgtctctg aggctgttac gaatgctata atacatggat atgaagaaga
     3061 cagttctaag tttgttttct taagatgtga gatagaagga aatactataa agattatagt
     3121 tgaagatgaa gggtatggaa tagaaaatgt ggagaaggca atggaaccac tttatacatc
     3181 aaaaccagaa cttgatagat caggaatggg attcacagta atgaaaagct ttatggacga
     3241 tgtagaggta agttctgtaa aagataatgg gactagaatt gaaatgacta aaaaaataaa
     3301 tgtgcctaaa taaagtccaa aagtgaggtt ttattatgga agtaactgtt gccagagaag
     3361 aaaaaaaacc tcttcttagt catgaagaga ctctagaact tattgaaaaa gttcaaaatg
     3421 gagatgaaga ggcaaaagaa atattaatat caagcaattt aggtctagtt aggagcgttg
     3481 tatctagatt tttaaatata ggatatgata gagaagattt atttcagtta ggttctatag
     3541 gcttaataaa atcaatatat aaatttgacc caaaatttaa tgtaaaattc tctacttatg
     3601 cagtaccaat gattttaggt gaaataaaga gatacttaag agatgatggt atgataaaag
     3661 tatcaaggtc gttaaagcaa atagctgtaa aggcaaagat ggaaagtgaa gctttaacta
     3721 aaaaattagg tagagagcca agtatagaag aattagctaa agcaatagat gtagaaaaag
     3781 aagatttagt aatggctatg gaagctaatt tcaatgttga gtatttgcaa ggagttattc
     3841 atgaagagga aggttctcca atatgcctta ttgataaaat aagcatgaaa ggagaaagtg
     3901 aagaagaaaa agtagtggat aacatattgt taaaagacat acttggaaga ctggataaga
     3961 gagagcgtca aataatagtt ctcagatact ttgaagacat gactcaaagt gaaataggag
     4021 agatgctcaa tatatcacaa gttcaagtat ctaggataga gaagaaagta ttgtctaagt
     4081 taaaagaata tatatcgtga taatacttat gatatgtaga ataacaaaat ataataaata
     4141 tattactaaa ataaaatgta ataacttttt atgttaagtt tttaaattat taaaagatac
     4201 taaaataata aaaagcatta aaaaagtaaa aatataaaaa caaggtgtct ttatggaaaa
     4261 atagattttt tctttattag gcatcttttt tattttttga ccaaacttta gatagtcaaa
     4321 ataaataata ggtttatttt tttaaaatta acaaataata ctttagagag gtgtttagta
     4381 tggataaaaa ttataaaaaa tatgtagacc aaataagccc aaaacctaca tatttaaaaa
     4441 actatacact tgcatttatt gtaggtggaa ttatttgtat gatagggcaa gcaataaatg
     4501 atttgtatat gaaagttgga ggtcttgata aactaggtgc tagttctgca acatcaataa
     4561 cattaatatt tataggggca tttttaactg gattaggagt ttacgaccta ataggaaaaa
     4621 gagctggagc tggttctata attccaataa caggttttgc taactcaata gtatctccag
     4681 caatggagta taaaagagaa ggctatgtat taggtgtagg tgcaaactta tttaaaattg
     4741 caggaccagt tttagtttat ggtataggtt cttctatttt atgtggaatt atttattata
     4801 tttttaagat gttttagatg atttttattt aatttaaatt ttattaatta tgaagaaggt
     4861 ataaaatctg aaaatagcta ctaaagtaac taattgaaaa ataattgtgc agatttaatt
     4921 aatattaaaa atttgaatag taaaatgcaa aattaaaaag gtgtgaaaat atgaaaaata
     4981 aaagaattgg aaaaagaaca gtcaagttag aaaataaacc aaccataata tcaactggaa
     5041 ctatagtggg tcctaaggaa ggtgaaggac cactaaagga ctattttgat atgattatga
     5101 ctgacgattt atatggtgaa aagacttggg aattagctga aagtaaaatg gtagagactg
     5161 catcccaaca agctatccaa aaggcaggta aaaaattgtc agatgtaaat tatatgctag
     5221 gtggcgattt aataaatcaa atagtgccag catcatttgc agcaagagaa ctggctattc
     5281 catttttagg tatatatgga gcttgttcta caatggcaga aggtctttgt ataggttcta
     5341 tgcttataga tggtggtttt gctgatttag tactgtcagg tacatcaagt cactattgta
     5401 cagcagaaag acaatttaga ttcccacttg aacttggaaa tcaaaaacca atgacagctc
     5461 agtggacagt tacaggagca ggaagtgtat tattagctcc taatggagac ggtccaaaag
     5521 taaagtatgt tactgttggt aaagtaatag atgagggtat tgatgatggt aataatatgg
     5581 gaccagctat ggctccagca gcaatagata ctatctactc ttactttgaa gatactaatg
     5641 atgacccaaa tagctttgat ataattgcta ctggagattt aggtactctt ggaaaacaga
     5701 tagcagaaga ctttctaaaa gaaaaaggtg tagatatatc aaaagtttat actgactgtg
     5761 gtatagagat gtttaacctt aaagaacaag atgtccactg tggtggaagt ggatgtgggt
     5821 gttcagctac agtgtttgca ggatatatat atgataagtt gagaaaaaaa gaatttaaca
     5881 aagtaatgct tgtatcaaca ggagcactac tttcaccgac aagtacacta caaaagcaga
     5941 caataccatg tgttgcacat gcagtagtaa tagtaaatga gtaggaagtg atataatatg
     6001 ttaatggact atgtaagagt atttattgta ggtggaatta tatgtttaat agcccaagta
     6061 atgatggatt atttcaaaat gcaaactcca tatgttatgg taacgtatgt aacaactggt
     6121 gtagttttaa cttttctagg actttatgag ccattagtta agtttgcagc agcaggtgca
     6181 acagttccta taataggatt tggatattca cttgctacag gagtaataaa atcaattcaa
     6241 agtgatggtt ttttaggtat ttttttagga ggtacaactg ctacagctgg tggaatagca
     6301 gcagctatat tctttggata tattatgtca gtagtattta ctccaaaagc aaaaccataa
     6361 atctttatta aaagaataat aagtttttga aataataact ttttataaag caggtggata
     6421 tcttttagat tccacctatt ttttatataa agaagcgttt acataattga agttgacaat
     6481 tatttacaac atagtgtagt attatattat caaaataaaa tgaagtgaag taggggataa
     6541 agatggtaac tattaaagat attgcaagga atctaggtat cagttattca actgtttcta
     6601 ggtgcttaaa caataatcct aatgtatctg aaaaaacaaa aaagaaagta gtagaagagg
     6661 caaatagact agggttccat tttaatgtaa atgcaagaaa tttagcaaaa aaagaaacta
     6721 acaggatagg ggtaatcttt tcaaataatt ttaatcatca agatactaga aagtttttta
     6781 gtgatataat ggatagttct ataaattcta ttgagactaa taaatacgat tttataatac
     6841 agcctaataa taacattagt ggtgatagta atgtatataa aatggtaaat ggacaaatgg
     6901 ttgatggatt agtaattgtg tctcaatcaa taaaaaaaga agagtatgat tttttaaaag
     6961 acaataattt tccacatgta tttatatatt ttaaaccatc ttttgtagga gaagtagaca
     7021 atttcttttg ggacgataac gtgtatggag gttatatagc taccaagcat ttaattgacc
     7081 atggtcataa agacataata acagtaactt cagatgatag gagttcaaaa atgcatgaag
     7141 atagaactaa gggatattta aatgctatgg aagaggcaaa tttaaagacc gaagtcatta
     7201 aatctaaaat ggattttgaa tctcaagttg aatttttaga aaaatatatt gataaaataa
     7261 aaaaagcttc agctatattt gtacaacaag atgtacctgc gatttctata atacaagagt
     7321 taaaaactac ttatggtata aatgtaccag aagatatttc cataataggg tataataata
     7381 ttgaattaat atcatatttt aggtcgcatt tatcaacaat agatgaccca agagagcaag
     7441 ttataaaaaa tggagtagat agtttagtaa atataataaa taaaaagagt acagaacaca
     7501 ttccaagaaa attatatcca aggttaataa tacgaaatag cgttaaaaga ataaagtagt
     7561 aagcttttaa gtatcaaaag tttattaaaa atattataga ttatgtgaag ttttttaaca
     7621 aacaatataa ataaaaatta aaaggagtag gtgtatataa gtacattgta ctcctttatt
     7681 tattgagata gtttttataa tatgaatgaa taattttatt caattatttg aaaatccgtt
     7741 attttaacaa tataaattaa taaattattt gtattttata tcatgaatct ataatatttt
     7801 tttgattcat aactaaaagt atataaaaat gatgaataaa tatatattat acattatcaa
     7861 tgataggtta tataataaaa tcactaacaa ttatattata agaaaattat aaaaattaca
     7921 aggaggtata gaaatgaaag aaaaagcagg gattagaaat gccataatag cagcctttat
     7981 aatcacaata ttggcagaat taattggacc tatttcattt aaagttatgg gaataaatgt
     8041 aactttactt agtatactat gggctatatt cataggaatg gctgtttctc ctcatttatt
     8101 agggagagtt ataccagcct taaaaaagtt tataggggat aatgaaataa atgtatctcc
     8161 atatttatta tctttgacac tatatccatt aggaataatg tttggaatta atgcagggcc
     8221 taaagttggt atattacttc aagcaggacc agcactttta ttacaagaat ttggtcatat
     8281 gggtacaatg ttgatagcat tacctgttgg agtagcatta ggtcttggaa gaagtgcatt
     8341 aggtggtact ttttcattat gtcgtgacac agcactaggc attattggag ataagtatgg
     8401 attaaactca ccagaaggta taggaacact aggaacttac ataagtggta gtatatttgg
     8461 aacattatta ttttcatttt tagcaccagt gggtgtactt ttaggatttc atccatatgc
     8521 tttagcaatg gcatcaggaa tgggtagtgg ttcaatgatg ggagctgcaa cagcatcatt
     8581 aatgaatacg gttccacaaa tgtcagagca gattttagca tattcagcta ctagtggatt
     8641 gattacagct gttactggaa tatatataga attattctta tctttaccag tagccaacta
     8701 ctattatagc aaagtagctc cagttattga aagatttaga ggaagaaaaa caagaagaac
     8761 aagtaataaa ttgtaaagga ggatatatat atggaaaaaa cttttaagac tattatggag
     8821 cagataaaaa tagtattgtt tatatatatt attacttgct ttggacaaat gatagcactt
     8881 aagactcagg ctcaagattt gttgattgga agtatatctg gatttttgtt ggtgataatt
     8941 gctattataa taaagaattt tgttaaaaaa cctaatttac caggttttgc atgggctaca
     9001 ttagttgcat tcgttttatc gcttccaata tctccagtgg gggatatcat agcaacaaat
     9061 gtagggaaaa tcaattttat gtctacagta acaccattat tagcttttgc aggaatctct
     9121 gtaggtaacc aattagatat attaaagact ttgagttgga agttagtagt tatatcattt
     9181 atagttatga catctactta ctttggttct gcttttatat ctcaaacagt tttaagatta
     9241 aatggaatgc tttaaggagg tagtaaatat gaatgaatta aaagcaaaaa ttaaagagga
     9301 aataaagtta ttatctgaag agaaaaagac atcatttgaa aaagtttctg actatttatt
     9361 ttcaaatcca gaattagcat ttgaggagta taagtcacaa aaagcattat gtgatttgtt
     9421 agaagaaaat gaatttaatg taactaaagg tgtaggagga ttagaaacat cttttgaagc
     9481 tgtgtattca aatggaacta atgggaaaac agttgctttt ctagctgaat atgatgcact
     9541 tccaggaatg ggacatgcat gtgggcacaa tatcataggg acaagttctg ttggtgcagg
     9601 tatcatatta aaagaaatca tgaaaaaaca taatatagaa gggactgtaa aggtttttgg
     9661 aacacctgca gaagaaagag taggtggaaa aataactatg attaaagaag gtgtatttaa
     9721 taatgtagat gctgcattaa tcttacatcc aagtgatgct tcaatgcctg atgatatatc
     9781 atttgctcaa gttaatttaa aatttgattt tactggtaag gcatcacatg ctgctgcttt
     9841 tccttgggaa gggaaaagtg ccttaagtgg agtaatagca ctatttaaca gtgtaaatag
     9901 catgagatta catcttaaag attatgcaag agtacatgga attataactg atggaggtag
     9961 catacataat ataattcctg aaaaatctac agctatattt aatgtaagag ccttaagcat
    10021 agaatattta aatgagattt gtgaaatgct taaaaattgt gctaaaggag ctgcaatttc
    10081 tactggaact aatgtagaaa tagttcaatt agatgaaata tacaaagaga ttaagaatga
    10141 ttctgaatta gtgaatatag ttagacaaaa ttttgaagtt ttgggtgaag actatgttga
    10201 aagagattta agtcaaggta taggttcaac tgatacagga aatttaactc atgagatacc
    10261 tgcaatacaa gcatatataa aattaaaaga aaatactgca actcatacag atgaatttgc
    10321 tgttgcagct ggtggtgaag aaggcaaagt agcacttata aaagcaatta aggtgctagc
    10381 aatgtgtgga gtagatattt tgtatagtaa ataatatata attttaaaat atattaagaa
    10441 aggaaatcgg attagacatg atattaaaac aagtaataga ggtttatgac attttagata
    10501 aagcaaatgc taatggggaa gaagtaaaaa cttacttaca aggttatggt gaagtagatg
    10561 taactgtaaa agaattgtct tcaagtaaag gttcaacaga tttagtaaag cttacaattc
    10621 ctgggaaaaa tggaaaatta aaaggtggag atgctcctac tcttggtatt ttaggtagat
    10681 taggagggat tggagcaaga ccagaagtta taggttttgt ctcagatggt gatggagcat
    10741 tggtagcaat tgcagtggct gctaaacttt tggatatgca acgaaaaggg gacatattag
    10801 atggtgatgt tgtaatttca actcatattt gcccagatgc tccaactaaa gaacactatc
    10861 ctactccttt tatggattct ccaattgata tgatgactat gaatgaaaat gaagttgata
    10921 gtagttgtga tgcaatactt tctatagata ctactaaagg aaatagagta atcaatacta
    10981 gaggatttgc aatatcgcca actgttaaag aaggctacat attaaaaact agtgataacc
    11041 ttttagatat tatgcagact gtaacaggga aatctccatt tgtattccct ttgtctattc
    11101 aagatataac accatatgga aacaatctgt atcacttaaa tagtatttta caaccagcag
    11161 tagctacaga tgcaccaata gtaggagtag caattacaac agagatgcct gttgctggat
    11221 gtgctacagg tgcaactaat tttagtgatt tagattcagc tgggagattt gcaattgaag
    11281 ttgccaagct atttggtaga aataagtgtg atttctatga taaagaagag tgggaaatgc
    11341 ttattaagag atatggcaaa ttaaatagat ttcaaacatt tggtatacag taattagaaa
    11401 aatattaagt ttatataatt tgtgatacaa ctatttaaga agatataaac aattaggaat
    11461 aaaagtaaga ataaagcact tagttaaaaa ctttaaaaaa aaatatttat ttgtttatat
    11521 aaaaaggagg attctggtta ttgggattct cttttttatg aatacaaata atatattgta
    11581 attataaaaa aaggagcgtt tcaaagtgat ttttttaatc accttgagac aactccttat
    11641 attttttatt taaattctat tttttattga ctgtatagct attttcacca tcataaggtg
    11701 gcatgacctt gaacagcgtg gttttgtaaa gttgggcacc acaaaacaaa aaatcaacaa
    11761 gcccttgtgt ggtctgctga cgtgtttact atactatact ttcccaaaaa ccgcaagcac
    11821 tatgggaggc tataaggcgg cgaccattca ggggcgatcc cctcgaaacc gggatagggt
    11881 tcccatgtgg gacataataa agagcgcccc ggaggtatca actaccatcc ggggcgctct
    11941 ttattatgtc ccgtgggaac catgcccacg aagcagggcg tacaacggac agataggtcc
    12001 taccctcctg acagactgga atctcaatcc catcgaaaac aatcataaca atcatggcaa
    12061 gattatatac actcctgtaa aatatttttg tgtgtaccat gaagtactgc ttgccactat
    12121 tgagaacgga taaaagggaa gtacgtatta taccaataag gtgaacgaaa caaaatactc
    12181 atttgataaa gttaaataaa cctgtcggaa ccccaccaat ccggcaagag ctcactcaat
    12241 ttaacagttt tttctgtttc gacattaact aaaatctcaa tacaagcact atccttatca
    12301 agttgcatta aatattcacg acaagcacca catggtgagc caacactccc attgctcatc
    12361 acacaaacta atttagtaat tttactttcg ccatttgtta tcatattggc gatagcattt
    12421 ctttctgcac acattcccaa tgtacaggct gtatcaatac acacgccagt ataaacattt
    12481 ccgctgtcgg taaggattgc tgcggcaacc ccaccagcat cgataaaagg tgaaattgtg
    12541 cgtggattta attttcccct agcattatta taaagttcct tccatttcat caggttgatc
    12601 ctcctgttgt atccatataa ataatctttt atacgccttt tccgcctaag gcacacaaca
    12661 cattactcgc ttttttcatt ctaatattcg tgcgtgaaaa tgtcaaacgg tttacttcgt
    12721 ttcattactt catactgctg ttcataaccc tgtttgttca cttgggcacc attcgagcac
    12781 caatttaccc gtttcagggt tgtagcgaac acagcagaaa tgctcatttc atgggctttt
    12841 ctggctagaa aaaaaatttt atcgctgcca gatatttact attttttatt aagttgctgg
    12901 agttccacca ccatcaggag gagtagtaga gccaccacca ttatttccac cattatcagg
    12961 aggagtagta gagccacca
//
LOCUS       DAEQJM010000092        12518 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.093, whole genome shotgun sequence.
ACCESSION   DAEQJM010000092 DAEQJM010000000
VERSION     DAEQJM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12518
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.093"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            253..2265
                     /locus_tag="KRQ43_003284"
     CDS             253..2265
                     /locus_tag="KRQ43_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2743624.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNALIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIDDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            2634..3854
                     /locus_tag="KRQ43_003285"
     CDS             2634..3854
                     /locus_tag="KRQ43_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2743625.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISSTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            3891..5240
                     /locus_tag="KRQ43_003286"
     CDS             3891..5240
                     /locus_tag="KRQ43_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH2743626.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYSLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWFIRIISWSTL
                     AVGFATALGSFWPESATEYKGCIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFVIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     IALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(5372..5665)
                     /locus_tag="KRQ43_003287"
     CDS             complement(5372..5665)
                     /locus_tag="KRQ43_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743627.1"
                     /translation="MISMIMMLIGVLFIVFGIILTAVEIKGKMPGFYGVGQNAVRKNA
                     IGIIAAGIALIFFRNGLDSIDSILTYGVFLVIELVVIGLYFLIRIKYDKDGNL"
     gene            complement(6149..6352)
                     /locus_tag="KRQ43_003288"
     CDS             complement(6149..6352)
                     /locus_tag="KRQ43_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743628.1"
                     /translation="MSFGKRIEMNNIGVETRGVCTIMCPYTCKMMASSSCNCKNNDYN
                     ARGGSYNTYYNKLIHGQRTPDGM"
     gene            complement(6403..6654)
                     /locus_tag="KRQ43_003289"
     CDS             complement(6403..6654)
                     /locus_tag="KRQ43_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HBH2743629.1"
                     /translation="MNYTEKELLLENIFFDVTGINFNKNNNLKKELFFSPSLHIQPRE
                     LLLVFCEVIENFNIKIPEEKLLNRQFTSFDNVLKIINMV"
     gene            complement(6670..7740)
                     /locus_tag="KRQ43_003290"
     CDS             complement(6670..7740)
                     /locus_tag="KRQ43_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HBH2743630.1"
                     /translation="MEKVLIYPFNYNFFTILNHCNKISDIEINSLVSPSGWGLCNKEY
                     NVNNIITKVTNDFQSELKKNSLVWFVDSKENLDLEKFIIPKLKVALKEGKKILYTRDD
                     LNKISRYISHYEFKKINEWNLEKYEIRDIEGISQINTPIIFICGLYGGLDTFDVNIRI
                     GEELRKRGFSILQFGPKKESYLFKMIPIPEFMFDDSISSKTKIINFNHFIKDKEVEAK
                     PDLIIIEVPGELFPFSRKMVGNFGIRAFEISNAVINDCGILCIPSSIYDREYCEELKY
                     FIKGRHGINIDYFSIEKKVIDTYETEVKQKFSYMSLDENFFVEDIEDYEKTFFIHDNK
                     QLLELVDNIVNQLKEYAKVISI"
     gene            complement(7769..9190)
                     /gene="ccpM"
                     /locus_tag="KRQ43_003291"
     CDS             complement(7769..9190)
                     /gene="ccpM"
                     /locus_tag="KRQ43_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HBH2743631.1"
                     /translation="MNQKPFIHTFKAGKSYFIYDVNTDKILKVNAAVYNYLNKIEHNL
                     EKESDWNIEIEDEINTLINYGFLKNKRVNKTMHPETKYIKYHIENNLSSIILQVTQNC
                     NLRCDYCIYSGSYSNRVHTNKRMNIDVAKRSIDYLIKNSSQLNEVSVGFYGGEPLLEF
                     DLIKQIVEYVKVVGEGKEIYFNLTTNATLFNEEIIEFFVKNNITTMISLDGGKEIHDK
                     SRKFANTGEGSHDVVLKNVRYIKNKYPEYYKKNITFNTVINSENDYISIDDFISKNET
                     LKDSNFLASTLNNNYSDKEIVSSDEYILGKSYDRFLTLLNKLKFIKDESMSPLSRIER
                     ALLDDFRYEKNIEGRLELPDVWHHGGPCIPGAFRIFVTTDGEFFPCERVSESSKMGMI
                     GNLDSGVDIEKAEKLLNIGKLYEEQCSDCWAYSYCDICIAKIDDTKCNENEIKPHDCD
                     RIRHSTENNMKDYCVLKSLGYQY"
     gene            complement(9212..10984)
                     /locus_tag="KRQ43_003292"
     CDS             complement(9212..10984)
                     /locus_tag="KRQ43_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743632.1"
                     /translation="MENGKFQFFKGVRNCFNMIYLHDKRYLFISMFMAIFQGIVPSIS
                     LLVSQNIINNMQTFSKSVKEILVLLIMYLIINIIPSIFQSFYGYYRIKFNKNFEKHIE
                     TMMLEKSLTLSLKDFEDDNTYDMINRAQSQKGFNITILSENLISIIRESVSTLSLIVV
                     LSQFQLWLIIVVIVIPVLKSLYSIKLGKEQYDVSVNRTWKERKAWYIDYLLSKGYAYK
                     EIMVFRIGSKLINHYKKLKEDIISQDMNIAKKNFIATLLCTVLDSIVSAGIIGFIIIQ
                     GILKKILIGDATTYIQAVQSIKDNVESIFSLFSSVIQDLFYTDLLFKFLDYNCKEDSI
                     EHIKIFEKIGDINKIELINISYKYNHSSEYSLKNINLTLNKNDPIAILGKNGSGKTTL
                     LKILLGFYDDYEGDILINGKNLKDIEKDEYIRKVSCMFQDYIKYEATLKENVAMGDVY
                     KSNLEEKVKSKLKETKLKPSIYEEDGLETILGTWFGKKQLSMGEWQKVAISRTLMKDA
                     DMYIFDEPDSSLDSEAGNELLSLYKKTFENKIGIFITHHIQHAKKITNNIVVLENGKL
                     LESGRHDELMDKKGVYFNLFCNCK"
     gene            complement(11257..11970)
                     /locus_tag="KRQ43_003293"
     CDS             complement(11257..11970)
                     /locus_tag="KRQ43_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743633.1"
                     /translation="MINIIICEGKKSERVILNDYINTFFYNYNFEYNIKEFENGGDLL
                     KKYPNNVDIIFMDIDLNDENGFNVSKEIKKFDESVRIIFVSSSNKYIKKGYEIGVYRY
                     LEKPLKYSLFKEAISSYLKECYKNEAILSIKCKCKIYFIKVDDILYLEVLKNDLTIHT
                     EKGIYTFKNSMKEIESNLEEHNFFRCHKSYLINLMKVNMLDIENNIVFINQNSIIVSR
                     YKIKLLREKLNSCLVDVII"
BASE COUNT         4731 a         1685 c         1375 g         4727 t
ORIGIN      
        1 aaattttttt gggtgtatat tataatttaa tcgaatagaa atgaaaaata tacatacagt
       61 ttaagtttta agcaacaatt agggggattt ggtgacaaga tttttaatta taagaaagaa
      121 agtgtcttaa tgcaactttt ataaagtcat tatagacact ttctttttta tttgataaat
      181 ttaaattatc aaaattacat tgctttatac aactattttg ttggaaacta tttattatat
      241 aaggagaaat aaatgaaaaa atcagtagct ctggtaaatg atagtagaaa agatttaata
      301 gactttttag aaaataattt gaaattagtt tttggagatt ctataaatat taatagatac
      361 ttcataaatg aaataaatga taatgatatt ataaatgatg atgtgatatt agtaatgtca
      421 gtagaaagat tagacaaaat tataaataat atactagata agaaaaaagt gattgtggta
      481 agaagaactt ttagggaaga taaaatttat aatctactat ctttaccaca gggtacaaat
      541 gctctaatcg taaatgattc tgatgaaact actctagaaa ctataagttt attttataaa
      601 attggagtga ctaatattag accaattcca tatatgaatg ataataacta taaaaatata
      661 aaaatagcta taactccagg agttccagaa aaagtaccta gctttatctc agatatattt
      721 gatttaggtc acagatatat agatatttct acatttatag aaataataaa tttattacaa
      781 attgattcaa aggaaataca atctaatcta gttaaatact cagaagaaat aataagttta
      841 gatactggta taaaagataa atataaggaa ttatttttaa aaatagaaga attagataca
      901 atattgaatt tatcaaaaga tggtatatta tttacttcaa aagatggtga aataaataca
      961 tataatagta aagtaaaaga tattttagac ataaatgagg atatatatgg aaaatacatt
     1021 gatgatatat ttgtagatag tttaaaagtt ttattgagtg agaaagagat actagataaa
     1081 gttgtcgtat tcaataagaa atatataaat gtaaataaaa aaaacatata caatagggat
     1141 gaaaaaatgg gcacatatta tagtttacaa gaaataacat acataaaaaa attagaacaa
     1201 aatctcacta aaaaattaag agaaaaagga caaatagcaa aatatacatt taaggatata
     1261 aaaacaaata gtcctaaaat gtttgaatgt atagatttag ctaagaaggt ttctaaatct
     1321 gacttaagca tacttatcag aggtgaaagt ggaactggta aagaactcat agctcagtct
     1381 atacataaca actcaaatag aaaaaatcaa ccttttatag cagtaaattg tgcagccgtt
     1441 cctgaaaatt tattagaaag ccagctattc ggatatgaca agggaacttt tactggaggt
     1501 ctaaaagatg gaaaacaagg attatttgaa cttgctaata atggaacaat attcttagat
     1561 gaaataggcg atatgccttt agaattacaa acaaaactac ttagagttct tcaagagaag
     1621 cagataatgc ctgttgggtc tcacaatgta attaatatag atgttagaat catatctgct
     1681 acaaataaga atttagaaca aatgattgat aatagccaat ttagagagga tttatattat
     1741 cgattaaata caattccaat aaatatacct cctctaagag aaagaaaaga agacatatta
     1801 attattatgg aagatttaat taataagaaa ttagtaatca caccagaagc aaaaaaactt
     1861 atacaaaact atatgtggaa aggtaatata agagaactcc aaaatgttac atcctattta
     1921 aacattatgt gtgaagatat tgtattagag aaagatttac ctccaaactt aaggtcttca
     1981 gataacaaaa atacatcatt aaaactaaaa tatagtaaga atgatatatt gaatatatta
     2041 gagatactaa ttttaaataa ggaatcagat gttggtattg gtaggggatt aattttaaaa
     2101 gcactactcg ataagaacct tcaaattaca gaaggaaaaa ttaaaaaaat atttgaatat
     2161 ctaaaaaaag aagaacttat aatttgtagt tcaggaagat atggaagtaa aataactcaa
     2221 aaaggagaag atttttacaa taaattaaaa tataaaggtc tataaaatta taatttatca
     2281 aacaaagaaa tctattcagg attaaagtac tccttcaata ggttttttta tttttcaagt
     2341 accctaaaat tataatttat tttgtacata aataatagga attaatagga ataggataat
     2401 ttttttattt cctatttttt ttatataaac tagcatataa aatatatttt cttcaaaata
     2461 atatttttta ctgaaaattg aaactatgca atcatttttt atactataca tatagataaa
     2521 tgattatatt tattcaatat tcttataaaa aacaaaattc tccatcgaaa attatggcat
     2581 aataattgct tattatatta ataaaacaat aaaaagcaat tggaggaata aaaatgcaac
     2641 aggctttgaa attaaaatat caaaccaaag aattaggaaa agattttgta atagaaagtt
     2701 gtaattctat aaaaccatgg cttataaaca taagaagaga attacataaa attccagaat
     2761 tagctcttga agaaaatctt actaaacaga aggtaatttc ttatttaaaa gaaatcggaa
     2821 ttgattatat ggaatttaca aaacacaatg gaattatggc atatatttta aaagaaagtg
     2881 cagataaaac gatttgtata agagcagata tggatgctct tcctattgaa gaagaaaaca
     2941 acatacctta taaatcaata cattctggaa aaatgcatgc ttgtggtcac gatgcacata
     3001 caaccatgct acttggagca tgtaaagttt tacattcaat aaaagataaa cttaatgtaa
     3061 atgtaaaatt cttatttcaa ccagcagaag aaggttttgg aggagcaaaa tttttagttg
     3121 aggatgggtg tttagaaaac cccaaggccg attatatatt cggacttcat gttatgccac
     3181 atatagaaac aggccttatc gaaacaaaat atgatacatt aaatgctagt gtagacacta
     3241 taaaaataag tatcaaaggt aaaagagctc atggtgcata tcctgaaaat ggtattgatg
     3301 caatagttac agcttcacaa attgttacat cattacaaac tataataagt agaaacttag
     3361 aaccaaataa tgctgccgtt ttgactatag gtaaaatata tggtggtgat gcacacaatg
     3421 taatatgtga agatgtaaaa ctagaaggca ctttaagaac cttaaatagc aaaacaagaa
     3481 actttatgat tgataaaata gctaaaattg ttggagacac tgcatctgca tttggttgtg
     3541 ttgggacttt acatgtaagt gatgaaaact atcctgctgt tataaatgaa aaagaattag
     3601 tagatacagt tatatcaagt actaaagaat tacttggaga ggaaaaattt atattgagac
     3661 caaacccgtc tttaggtggt gaagactttt ctttttacac agaacattgt aaaggagcat
     3721 tcttccattt aggatgtaaa aatgaggaaa agggcttaat ttcacctctt catacctcta
     3781 gcttcaatat agatgaagat tgtttaccaa taggtgttat gatgcatgta atgaatactt
     3841 tgtattttaa ttagtacagt aattaataaa agaataggag ataaattaat atggaaaaag
     3901 ctaagaaatt aggtctattt agtatgatat tattagggat taatagcata ataggttcag
     3961 gtatattctt actaccaggt aaagtttata gtctagcagg tcaaaacagt atgtttatat
     4021 acatttttgc tacactctta gttctatcaa tacttttatg ttttgcagaa gttggaagca
     4081 tgtttgataa gaatggagga gcatatctat actccaaaaa agcttttgga gattttatag
     4141 gatttgaagt tggtacaatg tcttggttta ttagaattat atcatggtct actctagcag
     4201 taggatttgc aacagcttta ggttcatttt ggccagaatc tgccactgaa tacaaaggtt
     4261 gtatagctgc aatactcgta acactacttt caataaatag cttatttgga attaaaagca
     4321 caaagataat gaataatgta ataactatag ctaaattagt accattaata gtttttgtga
     4381 tagttggaat attctttata aaatttgtaa atattgttcc ttcaggaaat gtagttaact
     4441 ctagtatggg tccagccatt atattagtat tttacgcatt taccggcttt gaatcattta
     4501 ttgtggcaag tggagaaatg gaaaatccta aaaaaaatct tccaatcgca ttaataacca
     4561 caatatttat atgtgcaata atttatatat taattcaaat tgtctgtatg ggtatacttg
     4621 gagatagact atttgaaaac agtattccaa ttgcagatgc ttcaagtgta tttttaggca
     4681 attatggtaa agttttcata tctgtagcaa cattaatatc tatatttggt ataaatatag
     4741 gttcatcaat agtaactcct aaatgtggtt cttctctagc agaagaaggt tctcttcctg
     4801 catttatagg aaaaacaaat aaatatggtg ctccatatgt agcaataata atatctttaa
     4861 tttgttgtat accacttgtg ctaactggaa gttttgaaca acttgcagta atgagtgtaa
     4921 ttgcaagatt tgctcagtac ataccaactt gtttatcagt aatagtttta agaaaaagaa
     4981 cagatgttaa ggcctctttt aagattccat ttggtcctgt tataccaatg gtagctattt
     5041 taggtagctt atggttgtta caacaagctt gggcagaaga tatttcaaaa cctataactc
     5101 aaaatagagt cttaatagga ttaggggcaa tgttgttaat agctcctcta tatatattta
     5161 tgaaaaaaaa taaggaaatc gagcataaaa ataaatcaga agattctaaa ttatatattt
     5221 cgagagaaaa aattcaataa tattttatac tattacttct cataaaatat aataaatata
     5281 aaaaaattgt agataaaact attttataaa atttatctac aattttttta tataaacata
     5341 tatcaaaatc aaaatattat taatttatac tttaaagatt cccatcttta tcatatttta
     5401 ttcttataag aaaatataat cctattacta ctaactctat cactaaaaat actccatagg
     5461 taagaattga atcaatacta tctaacccat ttctaaaaaa aattaatgct atacctgctg
     5521 ctataatccc tatagcattt tttcttactg cattttgccc aactccataa aaacctggca
     5581 tttttccttt tatttcgaca gcagttaaaa ttatcccaaa cactataaat aatactccaa
     5641 taagcatcat aatcatacta atcatctaat tacctccttc acttaaggaa atttcaattt
     5701 ctaaaatcta aaataaataa tatttatttt ttataataat attgtatatc caattaacta
     5761 ttttggaaat tagtaccaat aaataatgtt taaatattga aataatatat taattctaat
     5821 caatattatt aatatatata catttttaca aatatattta aaaactttac ttttaattct
     5881 tactatttaa ataagtataa tttattataa taacttttaa ttaatttata cttttaaatt
     5941 gtaaaaatca cccctaatca ctatatttac cactataata attgaagagg tgatttatat
     6001 aacagatact atttatgcag ttattataaa atcacactct taattataat caactgcata
     6061 tttttataat aaaaggaaat aaagtaagaa agataaattt aatcaaatat gctaaatcaa
     6121 tttaatagta tacttattac tgaaatattt acattccatc aggagttctt tgaccatgta
     6181 tcaatttatt ataatatgta ttatatgatc ctcctcttgc attataatca ttattcttgc
     6241 agttacaaga tgaagatgcc atcatcttac aagtataagg acacataata gtacaaacac
     6301 ctcttgtctc aacacctata ttattcattt ctattctttt tccaaaactc attcatatcc
     6361 tccccttttc tataagatca cttactttat acctttatta acctatacca tattgattat
     6421 ttttagaaca ttatcaaaac tcgtaaattg cctattcaaa agtttttcct ctggaatttt
     6481 tatattaaag ttttctatta cctcgcaaaa tactaaaagt aattctcttg gctgtatatg
     6541 taaagacggt gaaaaaaata attctttttt taaattgtta tttttattaa aattaattcc
     6601 agtcacatca aaaaatatat tctctagtag taattccttt tcagtgtaat tcataattaa
     6661 cctccaattc taaatagata ttactttagc atactctttt aattgattca ctatattgtc
     6721 cactaattct agtaattgtt tattatcatg tataaaaaat gttttttcat aatcttctat
     6781 atcttcaaca aaaaagtttt catctaatga catatatgaa aatttttgct tcacctctgt
     6841 ctcatatgta tctataactt ttttctctat actaaaataa tctatattta taccatgtct
     6901 tcctttaata aaatatttaa gttcttcaca atattctcta tcatatatac ttgatggaat
     6961 acataatata ccacaatcat ttattactgc attagaaatt tcaaaagctc taattccaaa
     7021 attaccaacc atttttctag agaaagggaa taattctcct ggaacttcta taattattaa
     7081 atctggcttt gcctctacct ctttatcttt tataaaatgg ttaaaattaa taatctttgt
     7141 cttactactt atcgaatcat caaacataaa ctctggtata ggaatcattt taaataaata
     7201 gctctctttt ttaggaccaa attgtaatat tgaaaacccc ctttttctta gttcttctcc
     7261 tatccttata tttacatcaa aagtatctaa ccctccataa agaccacaaa taaatattat
     7321 tggtgtgttt atctgtgata taccctctat atctcttatt tcatattttt ctaaattcca
     7381 ttcattaatc tttttgaatt cataatgaga tatataccta gatattttat taagatcatc
     7441 acgtgtatat aatatctttt taccttcttt tagagctact tttaatttag gaattataaa
     7501 tttttctaag tctagatttt cttttgaatc aacaaaccat accaaagaat tctttttaag
     7561 ttcactttga aaatcatttg taactttagt aataatatta ttaacattat actccttatt
     7621 gcataacccc cagccagaag gactaaccag tgaattaatt tctatatctg aaattttatt
     7681 gcaatgattt aaaatagtaa aaaaattata attaaatgga tatataagta ctttttccat
     7741 aatcccatct ttcctttcat tagaaaattt aatattgata tcctagagat ttcaaaacgc
     7801 agtaatcttt catattattt tctgtagaat gtctaattct gtcacaatca tgtggtttta
     7861 tttcattttc attacattta gtatcatcaa tcttagctat acatatatca caataactat
     7921 aggcccaaca atcagaacat tgctcttcat ataattttcc tatatttaaa agtttttcag
     7981 ccttttctat atctactcca ctatctaaat ttccaatcat acccatttta gaactttcac
     8041 ttactctctc acatggaaaa aattctccat ctgtagttac aaatattcta aaagcccctg
     8101 gtatacatgg tccaccatga tgccacacat ctggtaactc taatctacct tcaatatttt
     8161 tctcatatct aaaatcatct aataaggctc tttctattct tgataaaggt gacatactct
     8221 catcttttat aaattttaat ttgttgagta aagtcaagaa tctatcataa ctcttaccta
     8281 atatatattc atctgatgaa actatttctt tatcagaata gttattatta agagtggaag
     8341 ctaaaaagtt tgaatctttt aaagtctcat ttttagatat aaaatcatct atagaaatgt
     8401 aatcattttc tgaatttatc actgtattaa atgtaatatt ctttttataa tattctggat
     8461 atttattttt tatgtaacgt acatttttta atacaacatc atgagatcct tctcctgtat
     8521 ttgcaaattt tctactttta tcatgaattt cttttcctcc atctaaacta atcatagttg
     8581 ttatattatt ttttacaaag aattctatta tttcctcatt aaataaagtt gcatttgtag
     8641 ttagattaaa gtatatttcc tttccttctc caactacttt tacatattct actatctgct
     8701 taatcaaatc aaactcaagt aagggttctc ctccataaaa gccaacacta acttcattta
     8761 attgactaga attcttaatc aaatagtcaa tacttctttt tgctacatct atattcattc
     8821 ttttatttgt atgaactctg ttgctgtatg aaccagaata aatgcaatag tcacaacgta
     8881 aattacaatt ttgggttact tgtaaaataa tagaggatag attattttct atatgatatt
     8941 ttatatactt agtttcaggg tgcattgttt tatttaccct tttatttttt agaaatccat
     9001 aattaatcaa ggtattaatt tcgtcttcta tttctatgtt ccagtcactt tctttttcta
     9061 aattatgctc aattttattt agataattat aaacagcagc atttaccttt aaaatcttat
     9121 ccgtattaac atcataaata aaatatgatt ttccagcttt aaatgtgtgt ataaatggtt
     9181 tttgattcat taattaacct ccctttaata tttatttgca gttacaaaat aaattaaaat
     9241 aaacaccctt tttgtccata agttcatcat gtcttccact ttctaacaac tttccatttt
     9301 caagaactac aatattgtta gttatctttt ttgcatgttg gatatggtgc gttataaata
     9361 ttccaatctt attttcaaat gtttttttat ataaagaaag gagttcattt cccgcttcag
     9421 aatctaaaga tgaatctggt tcatcaaaaa tgtacatatc agcatctttc ataagagttc
     9481 tagatattgc tactttttgc cattcaccca tagaaagttg cttcttacca aaccaggttc
     9541 ctaaaatagt ttctaatcca tcttcctcat aaatacttgg tttcaattta gtttctttaa
     9601 gtttactttt aactttttct tccaagttac tcttatatac atctcccatg gcgacatttt
     9661 cttttaatgt agcctcatat ttaatataat cttgaaacat acaacttact tttctaatgt
     9721 attcatcttt ttcaatatcc tttaaatttt ttccatttat caagatgtca ccttcataat
     9781 catcataaaa acctaataat atttttaaaa gtgtcgtttt acctgaacca ttttttccta
     9841 gtatagcaat aggatcattt ttatttaaag ttaaattaat attttttaaa gaatactctg
     9901 atgaatgatt gtatttatat gaaatattta ttaactctat tttatttata tcccctattt
     9961 tttcaaatat ttttatatgt tcaattgagt cttctttaca gttataatct agaaatttaa
    10021 acagtaaatc tgtataaaaa agatcttgta ttactgaact aaataacgaa aatattgatt
    10081 caacattatc ctttatagat tgaactgctt gtatatatgt agtcgcatct cctattaaaa
    10141 tcttctttaa aataccttga attattataa atcctataat tcctgcagat acaattgaat
    10201 ctaaaactgt acataatagc gtagcaataa aattcttttt agctatattc atatcttgag
    10261 atataatatc ctcttttaat tttttataat gattaataag tttagaacca attctaaata
    10321 ccataatctc tttgtaagca taaccttttg acaacaaata atctatgtac caggcctttc
    10381 tttctttcca agttctgttt acactaacat catattgttc ctttcctaat ttaatggaat
    10441 ataatgattt caatacagga ataacaataa caactattat tagccaaagt tgaaattgtg
    10501 ataatacaac aataagagaa agtgtagata ctgattctct tattattgaa ataaggtttt
    10561 cagatagtat agtaatatta aatccttttt gagattgagc tctatttatc atgtcataag
    10621 tattatcatc ctcaaaatct tttaaactca aagttaaaga tttctctaac atcattgttt
    10681 caatatgttt ttcaaaattt ttattaaact ttattctata atatccataa aaactttgaa
    10741 aaattgaagg aattatattt atgattaaat acataattaa caaaactaat atttctttta
    10801 cacttttcga aaatgtttgc atattattaa tgatattttg acttactaac aaagaaatag
    10861 atggaacaat cccctgaaaa attgccataa acatagagat aaataaatat cttttatcat
    10921 gtagataaat catattaaaa caatttctta cacctttaaa aaattgaaat ttaccatttt
    10981 ccacaataca cctccatact taataaaatt gaaataaaat attttattaa ttaatataat
    11041 ataacattat tttattatgt ataatacata tttaaatttt aaattaaatc tttaaaataa
    11101 aattgttaat agaattgtaa aataaaatct taatatattc aatctgttat tgatgaaagg
    11161 tatattttta actataatta gtttttatta taaatttttt catattttac aatagatata
    11221 ttctattaga atagaatata agggcaaaaa tttacctcaa attattacat ctaccaaaca
    11281 actatttaac ttttctctca ataattttat cttataacga cttacaatta ttgaattttg
    11341 atttataaat acaatattat tttctatatc tagcatattt accttcatta aatttataag
    11401 gtagctttta tgacatctaa aaaaattatg ttcttctaga tttgattcta tttctttcat
    11461 actattctta aaagtatata ttcctttttc agtatgtata gttaaatcat tttttaaaac
    11521 ttctaaatat aaaatatcat ctacctttat gaaatatatc ttgcatttac attttataga
    11581 taaaatagct tcatttttgt agcattcttt taaatatgat gatattgctt ctttaaatag
    11641 agagtatttt aagggcttct ctaaatatct ataaactcct atctcataac ctttctttat
    11701 gtatttattt gatgaggata caaatataat tcttacactt tcatcaaatt ttttgatttc
    11761 ttttgaaaca ttaaatccat tttcatcatt taagtctata tccataaata tgatatcaac
    11821 attattagga tactttttta ataaatcgcc tccattttca aactctttga tattgtattc
    11881 aaaattgtaa ttataaaaaa aggtatttat ataatcattt agaattaccc tctctgattt
    11941 tttaccttcg caaataataa tattaatcat attacacccc ttatataatt ttttatttta
    12001 aattttataa aattctatct aacatttatt atatttcaaa tttaaagata ttttttaata
    12061 caaaattttt gtataataat aattattatt taatctaaat atatctatat tttatacatt
    12121 tatacataaa ttacttataa ttattatatc ttatacttta aatatttaat aattataaat
    12181 ttttacaata atattatttg tgtttttatt taaatacaaa tacagtataa attctaatta
    12241 atagttgcag tatatgtata ataaatctct tgtaataatg ttatttataa gtttacatcc
    12301 atttgaagga tatgttctct ttttattaca attctcacct tttagattat cactaaatca
    12361 atacttataa tattttctat atttatcttt acaaataaca actttttaca taaaataatc
    12421 atccctaaaa actatattac caatacttat taaaattttt ttatttaaat atcactctcc
    12481 tcacttttat tatttttata caacaatttc tattaata
//
LOCUS       DAEQJM010000093        12161 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.094, whole genome shotgun sequence.
ACCESSION   DAEQJM010000093 DAEQJM010000000
VERSION     DAEQJM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12161
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.094"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     regulatory      287..397
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            501..872
                     /locus_tag="KRQ43_003294"
     CDS             501..872
                     /locus_tag="KRQ43_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HBH2743634.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQDNKKTPKWTENVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            968..1915
                     /gene="trxB"
                     /locus_tag="KRQ43_003295"
     CDS             968..1915
                     /gene="trxB"
                     /locus_tag="KRQ43_003295"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH2743635.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            2000..2317
                     /locus_tag="KRQ43_003296"
     CDS             2000..2317
                     /locus_tag="KRQ43_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HBH2743636.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            2586..3872
                     /locus_tag="KRQ43_003297"
     CDS             2586..3872
                     /locus_tag="KRQ43_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH2743637.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            3984..4457
                     /locus_tag="KRQ43_003298"
     CDS             3984..4457
                     /locus_tag="KRQ43_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:4116..4118,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HBH2743638.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            4489..5799
                     /gene="grdB"
                     /locus_tag="KRQ43_003299"
     CDS             4489..5799
                     /gene="grdB"
                     /locus_tag="KRQ43_003299"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:5536..5538,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH2743639.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            6056..7588
                     /locus_tag="KRQ43_003300"
     CDS             6056..7588
                     /locus_tag="KRQ43_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HBH2743640.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNSDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            7599..8744
                     /locus_tag="KRQ43_003301"
     CDS             7599..8744
                     /locus_tag="KRQ43_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HBH2743641.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            9054..10133
                     /locus_tag="KRQ43_003302"
     CDS             9054..10133
                     /locus_tag="KRQ43_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH2743642.1"
                     /translation="MSRVKNVVGLLGTKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            10246..10845
                     /locus_tag="KRQ43_003303"
     CDS             10246..10845
                     /locus_tag="KRQ43_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743643.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLPPKGQE
                     SSQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIAALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(11032..11904)
                     /locus_tag="KRQ43_003304"
     CDS             complement(11032..11904)
                     /locus_tag="KRQ43_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH2743644.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
BASE COUNT         4760 a         1358 c         2324 g         3719 t
ORIGIN      
        1 atataaaaag tgattatttg ttgtgaaaat agtcttgttt ttaactaaat tgataaaata
       61 aactaaaaaa gatttgtact taaaaaaaaa agaaaataca agaaatatgc aatatcaaca
      121 tttggaaaaa aaagtaaaaa tgtatacaaa atacatataa aaaaactatt gcaaatttta
      181 tagaatgttt atatacttaa gtcaacagag atagaaaaaa gctatttata gaaaacaaag
      241 gataaattgc ttaattttaa attttctgaa aaaaataata atccggatga agagtatggg
      301 agactgcttt ataaaaagcg accgaaggga caagtttaat cttacttacc caaaagatta
      361 gatgaaattc tcaggtaaag gtgactgtac ttggacgggg ctctgaaaat gattttaaca
      421 gggaagacaa attgggagat ttgtttttcc tgttttttat ttatcaagta ataaataaaa
      481 gtttgaaaga gagtaaaaaa atgataataa ttacgaataa tccaaaagta aaagaagaag
      541 ttcaaggcag agaagttttg tttaaagaca caacttatat tggaatctta gaagcaagta
      601 gagatttgat acatgaaggt tatgaacttt tatctcatcc actctatggg agtgtaaaac
      661 caaatgaaac accttacagg actgttatac taaagaaagg aaatcgtttg gatataaact
      721 ctttaacctt aattgaagaa gcaatcatca ctgcaagtaa atttcaggat aataaaaaga
      781 ctccaaaatg gacagaaaat gtccaagacg attttagagt aattgattat gatatatttt
      841 ataatacaat acaaagaatg cagtatgaat aaaaaaattt gttaaaaagt tattgaaaca
      901 gcctaaatat taaatctaat ttaatattaa ataaaatgag aaatttaatt ggggaggata
      961 agtcaaaatg gaaaatgtgt atgacttagt aataattggt tcaggaccag ctgggcttgc
     1021 agcaggtctt tatggagcaa gagcaaagtt aaaaactcta atcctagaaa aagacaagac
     1081 tggtggacaa attgtaataa cacatgaaat tgcaaattat ccagggtcag ttccaaatgc
     1141 aacaggacca agtttaatag ctagaatggt tgaacagtgt aaagagtttg gagcagaaat
     1201 gctaagagat aacattgttg atactgagct agatggagat ataaaagttt taaaagggga
     1261 aaaggcagaa tatagagcaa aagcagtaat aataggaaca ggagcaacac caagaaagat
     1321 tggttgtcct ggagaaaaag aacttactgg taaaggggtt tcatattgtg caacttgtga
     1381 tgcagatttc tttgaagatt ttgaagtatt tgttgtaggt ggaggagaca gtgcattaga
     1441 agaagcaatg tatttaacta aatttgctag aaaagtaaca attgtacata gaagacaagg
     1501 atttagatgt gctaagagtg ttgaagaaaa agcaaaagct aatccaaaga tagagttttt
     1561 attagataca gtaattgaag aaatcaaagg tgatggaata ttagaatcag ttgtatttaa
     1621 aaataaagtt actggagaaa ctcatgaata ctttgcagat gaagaagatg gaacaatggg
     1681 agtatttgtg ttcgttggat tagatgctca aactgattta ttcaaaggta aagttgatat
     1741 ggatgaaaaa ggttacataa taactgatga agatatgaga actaacatac caggcgtatt
     1801 tgcagcagga gattgtagat ctaagactct aagacaggtt gtaactgcaa ctaatgatgg
     1861 cgcaattgca tctatagtag ctgagaaata cattgatgaa aaatttggga actagaatct
     1921 gtaaattaag aaatagtgtc tgtaaattta atgaataata tttaaaatta aaataaaaat
     1981 ttcaaggggg aataagaaaa tgttagattt agataaggct acatttgaag aagaagtttt
     2041 aaatgcagaa ggttttgtat ttgttgattt ttggagtgaa ggttgtgagc cttgtaaagc
     2101 tttaatgcca gatgttcata aattagctga gacttatggg gataaaataa aattctgtaa
     2161 gatggataca acaaaagcta gaagattagc tataaaacaa aaagtattag gtcttccaac
     2221 tatggctata tacaaagatg gagaaaaagt agacgaagtt actaaggatg atgctacagt
     2281 tcctaatata gaaaacatga ttaaaaaata tctttaatat gttgataaag tattaacatt
     2341 aaaagaaaaa atctattttt atctgaagat aagaagaaaa aggtttttat gtccaacttt
     2401 gttaaaaaaa taattttaaa taaaataatt tttttacaat aaatattttt tagtaataaa
     2461 ataaagattt aaggcataaa aacacaataa tatatcttta aaaaaataag ataaattgta
     2521 aaatgatata attttgagaa aaactcaaat gcatatacac aaattaaata acaggaggtg
     2581 caagtatgcg tcttgaatta gggaaaatct ttataaaaga tattcaattt ggtgatgtaa
     2641 cagaagtaaa agatggagta ttattcatca ataagcaaga gatgctacaa gaaattggtg
     2701 gagatgagca tattaaatct atagatatag aattagctcg tccaggtgaa agcgtaagaa
     2761 taacacctgt aaaagatgtt attgagccaa gagtaaaagt tgaaggtaat gggggaatct
     2821 tccctggtat catgtctaaa gttgatactg taggagaagg aaaaactcat gctttaaaag
     2881 gtgtagctgt tgtaactact ggaaaaatag taggtttcca agaaggtata atagacatga
     2941 ctggagaagg agctaagtat actccatttt ctaaattaaa taatgtagta gtaatagctg
     3001 aacctattga tggtttaaaa caatacgctc atgaaaaagc tgttagaatg ataggattca
     3061 aagcagcaat gtacttagga gaagtagcaa gaaatcttac tccagatgaa gtttcagtat
     3121 atgaaactaa acctcttctt gaatcaataa aagaatatcc agagcttcca aaagtaggat
     3181 atgtttacat gcttcagact caaggtttat tacatgatac ttatgtatat ggagtagatg
     3241 caaaacaaat agtaccaact ttattatatc caacagaatt aatggacgga gcaattgtaa
     3301 gtggtaactg tgtttctgca tgtgacaaaa acccaagtta tgttcatata aacaatgggg
     3361 ttgttgaaga cttatatgca cgacatggta aagatataaa ctttgtaggt gtaattataa
     3421 ctaatgaaaa tgtttaccta gcagataaag aaagatcttc aaactggact tctaaattat
     3481 gtaaatattt aggattagat gcagttatag tttcacaaga aggttttgga aatcctgata
     3541 ctgaccttat aatgaactgt aagaagatag aaatgcaagg tgttaaaaca gttatagtta
     3601 cagatgaata tgctggacgt gatggaggtt ctcaatcact tgcagatgca gatgtaagag
     3661 ctgatgctgt tgtaacaggt ggaaatgcca accaagttgt agttcttcct aagttagata
     3721 aagttattgg acatttagaa gtagtagatg taatagctgg tggttctgat ggaagtttaa
     3781 gagctgatgg aactattgaa gttgaaatcc aagctataac aggtgcaact aatgaaacag
     3841 gatttggtca tttaactgct aaaggatatt aagaagtatt ttattaaacg attgagtaat
     3901 gttaataaaa catattatag ataattataa taagtgttat agatatataa aaatatatta
     3961 gaaatataat aaggaggatt attatgagtt tacttagtaa taaaaaggtt cttataatag
     4021 gtgaccgtga tggtatacca ggacctgcga tagaagaatg tgtaaaaaca gtagaaggag
     4081 cagaggttgt tttctcatct acagaatgct ttgtctgaac agctgctggg gctatggact
     4141 tagaaaatca aaacagagtt aaagatgctg ctgataaatt cggagctgaa aatgttgtga
     4201 ttttactagg tgctgctgaa gccgaagctg caggtcttgc agccgaaaca gtaactgctg
     4261 gagatccaac tttcgctgga ccacttgctg gagttgcctt aggattaagt gtttaccacg
     4321 ttgttgagga accaataaaa tcattatttg atgaaagtgt atatgaagac caaataagta
     4381 tgatggaaat ggttttagaa gttgaagaaa tagaagaaga aatgtctggt ataagagaag
     4441 aattttgtaa attttaatgc ctaaaagcaa aaggggtgaa actaagagat gggaaaacta
     4501 aaagcagtac attatattaa tcagttcttt gctggtatag gtggagaaga aaaagctgat
     4561 actaagccac atgtggcaga aactttacct ccaataagtt tacaacttga taaattatta
     4621 ggtgaagata ttgaaatagt tggaacagta gtttgtggag atagctattt caatgaaaat
     4681 attgatagtg caagtgaaga agttttatca atggtaaaag gttttgaacc acaacttttc
     4741 atagctggtc ctgcatttaa tgctggtaga tatggggttg ctgctggaac aataactaaa
     4801 gttgtaaaag atgctttgaa tataccagct ttaacaggta tgtatgttga aaatccagga
     4861 gcagatatgt tcaaaaagga tgtttatgta gtagaaactt ctgattctgc agcaggtatg
     4921 agaaaggcac ttcctaagat agctaaactt gcagtaaaac ttgctaatgg agaagaaatt
     4981 ggaactccta aagatgaagg atacatagct agaggaataa gagttaacta cttccatgaa
     5041 gacagaggtt ctaagagagc tgttgacatg ttagttaaga aaataaaagg tgaaccattt
     5101 gaaactgaat acccaatgcc aaactttgat agagttgacc caagtaaagc tgtaaaagat
     5161 ttatcaaaat gtaaaatagc tttagttact tctggtggta tagttccaaa aggaaatcca
     5221 gatagaatag agtcttcttc agcttctaaa tatggaactt attctatagc aggagttatg
     5281 gatttaacag aagagactta tgaaactgca catggtggat atgacccagt gtatgcaaat
     5341 ttagatgcag atagagtatt acctgttgat gttcttagag atttagaaaa agaaggtgta
     5401 attggaaaat tacatgagac tttctataca actgtaggta atggtacatc tgttgcaaac
     5461 tctaaaaaat atgcttctga aattggagca gcattagtgg ctgatggtgt agatgcagta
     5521 atattaactt ctacatgagg tacttgtact cgttgcggtg caacgatggt aaaagaaata
     5581 gaaaaaactg gacttccagt agttcatatg tgtacagtag tacctatttc attaacagta
     5641 ggggctaata gaatagttcc aactatagca atacctcatc cacttggaaa tccagcgctt
     5701 gaccctacag aagaaaaagc cctaagaaga ggccttgtag aaaaagcatt aaatgcttta
     5761 actacagaag tagatggtca aacagtattt gaaaaataaa aataacacac acatatatta
     5821 tatagataaa aatataaaca cacactaaaa ataaaaaata actatacaca aaaaaaataa
     5881 tatagatttc atgaatggat aaattggagt tattcattca tgaaatctta aaaaatgcca
     5941 aaatacataa acaataatag aatcaaatat acaataaaat acaatgatta gagcttttaa
     6001 taagtttaat aagattaaaa aataagtgtt cataaaattt atggaggtgc acaaaatgac
     6061 ttatccagtt ttaaaagggg caggctatgt acttattcat actccagata tgatagtgca
     6121 aaatggaagt acttgtacag ttgaaagagc aacaaattca gattcagaat ttttaaaaga
     6181 agtaagtaat catataagaa gttatgaaga tgtagttaac tacatgccaa atcaagttta
     6241 tataggaaat agaagaccag aagaattaag agatttacca atgccatggt gtgaacaaaa
     6301 gattgaggga actagaaatg gtaagtttgg agaaataatg cctcaagatg agttcatagc
     6361 tttaatgcaa ataagtgatg catttgattt agtaaaatta tcacaagaat ttattgatga
     6421 agtaaagcca aaaatcgaaa ataactaccc tgaaattgca ccatttgtag gtaaattaaa
     6481 gggtgatgat atagaagaag gtaaagaatt agtagcaaca cacatagctg aaggattata
     6541 ccatgatgga aaatttgttg gttatgtaaa aagagcacat gatgtagatg ttaacttaaa
     6601 tgcccataca atgtttgaaa atctagtagt aaaagcatct ggagttttat ctgctattca
     6661 aatgctaaga catagcaaaa tagaccctgc tgaaatagat tatgttattg agtgttcaga
     6721 agaagcttgt ggagatataa accaaagagg tggaggaaac tttgctaaat caatagctga
     6781 gatagcagga cttcagaatg caactggttc tgacacaaga ggattttgtg cagcaccaac
     6841 tcatgcatta attcaagcag cagctttagt aaaagctggc atacataaaa atgtaatggt
     6901 agtagcaggt ggagcaagtg ctaaacttgg aatgaatgct aaagaccatg ttaaaaaagg
     6961 tcttcctgta cttgaagatg ttgttggagg atttgcagta cttgtatctg aaaatgatgg
     7021 tgtaaatcca gttataagaa ctgatttaac aggtaagcat actgttggaa ctggttcttc
     7081 accacaagca gttatgacag cacttataac ttcaggtctt gatagagcta atttaaaaat
     7141 aacagatgtt gatgtgtatt cagttgaaat gcaaaaccca gatataacta agccagcagg
     7201 agcaggagat gttccagaag caaactacaa aatgataggg gcacttgctg ttaaacgtgg
     7261 agacttagaa aagaaagaat tgaaagattt tgtttctaac aaaggattac caggatgggc
     7321 accaactcaa ggacatatac catcaggagc tccttatata ggatttttaa tagatgattt
     7381 aactacagga aatagaaata gagctatgat agttggaaaa ggtagtttat tcttaggaag
     7441 aatgactaac ttatttgatg gagtatcttt tatagctgaa agaaatacag gtgttactga
     7501 agagacttca ggaatatcta aggatgaaat taagaagata atagctgaat ctatgaaaaa
     7561 actagcatta gatatgttag aagaataggg gtgaggatat gtcaaaaaaa gtaatcgcag
     7621 atgtattctt agaagtagct aatgcaatag aaagcggcga atttggcaaa aaagtaaaaa
     7681 ttggtgttac tacacttgga agtgaacatg gtgtagaaaa catggttaat ggtgcacaat
     7741 tagcaaaatc taatttattt gatattgtgc ttattggacc aaaagtggaa actgaccttg
     7801 aagtagttga agttaatgat gaaaaagaaa tgcatgcaaa aatggaagaa ttattagatt
     7861 caggatatat tgatgcttgt gttactatgc attataattt tccaataggt gtatctacag
     7921 taggtagagt aataactcca gcaaaaggaa aagaaatgat acttgcaaca acaacaggaa
     7981 caagtgctac taatagaata gaggcaatgg taagaaatgc catttatggt attgctacag
     8041 ctaaatcaat gggtaacaaa tgcccaaaag ttggaatact taatgttgat ggagcaagac
     8101 aagttgagaa gtgcttaaaa gaattaaaag ataatggata tgacatggag tttgcggatt
     8161 caattagagc agatggtgga tgtgtaatga gaggtaatga tttacttgta ggtgcacctg
     8221 atgttatggt tactgataca ttatctggaa atatatttat gaaagtattt tcttcatata
     8281 ctacaggtgg agattatgaa gctcaaggct ttggatacgg acctggagtt ggagaagact
     8341 atgatagaaa ggtacttata gtatcaagag catcaggttc tccggtagta gcaaatgctt
     8401 taaaatacgc ttatgatgtt gtaaagggag atataagtaa tgttgcaaga aatgaatttg
     8461 caaaggttaa aaaagcaaaa tttgatgaca ttatatcctc tcttactaaa aaagaagtta
     8521 aagctgaaaa agtagaagtt aaaatgccag ataaagaaat tgttactcgt caaatagctg
     8581 gtgttgatat aatggattta gaagatgcag tatctgagtt atggaaaaac ggaatctatg
     8641 ctgaaagtgg tatgggttgt acaggtccaa tagttttagt aaatgaagct aaaggagact
     8701 tagcagttga aactttagtt aaagctggat atactgcaaa ataagtacat tttttatatg
     8761 taaataagaa catatagtta taattttatt gattataatt atatgttctt tttattttat
     8821 atcttgtcaa tatttatata ttaacacaat ccatttattt gattctctag ctaatttatt
     8881 atatttattc aattaaaatt aagctttcta actaaataaa aactaatgaa gtattaaaat
     8941 gaaattaata aaatatgaaa aaattttagg aataaagtat ctgttagata aaaataagat
     9001 taattagtga tataatataa ttaagataaa atttattatt tggaggtaaa atcatgagca
     9061 gagtaaaaaa tgtagtagga ttgttgggaa ctaaaggtgt tgatgcacta tatctaacaa
     9121 agaaaactaa tgtaaactat ataagtggtt ttcctgatga agaagcatat gcagtgattt
     9181 gcaaagatgg aaacttttta gttactgata gtagatatat ggagcttgca gaaaaggttt
     9241 gcaaagattt tgaaattata aattggcata attttgatag aagtgtggca aaggcagtta
     9301 aaagtgtatg tgataaagtg ggtataaaga aacttgggtt tgaaagaact aatatagtgt
     9361 ttgataaata tgaagaactt aaaaatctga ttgagaagga taatggagaa ttaataccta
     9421 cagaaaatat tgtagagact ttgagatatg taaaagacaa agatgaaatc aaaaatacaa
     9481 gaaaagcttg tgaaatagcg gataaggcat tagaagaatt gattccacat ataaaagctg
     9541 gagttagcga aattgaactg gctacaaagt tagagtactt tatgaaaatg aacggagcac
     9601 aaaatatagg gtttgaaact atactgatat caggagcaaa gacttcattg cttcatggta
     9661 agcctagtga taagattata gaaaaaggtg attttgtact tatagactat ggtgctatgt
     9721 ataatggcta tatatctgat acaactagaa cttttatagt tggaggagct tctgaaaagc
     9781 aattagaaat atataattta gttaaggaag ctcaaaatgt aggggttgag aacatgaaag
     9841 ctggtgtaca tgcgacaatt ccagatgctg agataagaaa agttgtcaaa aaatatgaag
     9901 actattacta tcaaggtata ggacatggag tcggtaggga tgttcatgaa gaacctttca
     9961 ttggtaatta tggtgataaa atcatagaag agggatgtat aataacaatg gaaccaggta
    10021 tttatttccc tggatggggt ggagttagaa tagaagatac tgttttgatt actaaaaatg
    10081 gtccagaaag acttactaaa ttccctaaag atttgatgat tttagacaaa taatttaatt
    10141 tatatatatt tttttacata aaatataaca taatctcact attaagctct atttacatat
    10201 tatagtaaag agggcttaat tttattgtaa gaggtgatag tatatatgta taaaaaacat
    10261 aaatttataa aaaatataaa aaaagcctgg tataaaatca aattaattga tagatgcctt
    10321 ataattgtaa tggcaatatt aatgtttcaa tctatatata atttatttgt taatgaagta
    10381 aattcacaag atactacaac tattgatgta gtagtaagaa ccacttcagc agctatattt
    10441 gggtattttt taagtgctaa ttttataaag agacctttaa ggaagtatac aaatactgat
    10501 gtatcttcaa atctttttat agataataat ttacccccaa aaggtcaaga gtctagtcaa
    10561 aataatataa tgaatgtcaa aaataccatt ggatttactt cagaagctga taattatgaa
    10621 aagaaaatac ctattaataa taatgaaggt tttgaagaag gagaaactag tgaattgcaa
    10681 attattatag ctactgtaat ttgtatagca gcattaacag tactttttgt tgtaagaaat
    10741 tttacaacta caacatcagc ttctttaggt actatttcac agatgagaga ttttgtctca
    10801 ggatgcgtgg gttttttgct aggttgtcca agtaaacctg attaaaaaag tattatcaat
    10861 aaaaggtatt ttaaaaagta tcagtataat aatatttaga tttaaatgta tacaattata
    10921 attctataac attctatatt gtatttttat actgatactc taaactatac tatttattaa
    10981 aatattttaa cattgtattt aaacaaaata ttatatctgt ataatataaa tttagtttat
    11041 atgaatagat gccatatact caataaaaag tttcatacta tgagatatgt attgatttct
    11101 tctccaaaga actccaatat ttgcagtaat tgcacgttct aatggtattg aacagagatt
    11161 ttctgtattt tgaaatattt ctttatacaa tattgttgaa gccaagtcat tttctagtaa
    11221 ataacgtatg gtagaaagtt gatttgagtg taaaattata tttggcttag ctttttcaag
    11281 tctttttgta ataatcttat agtgataaga accttcagat aagattacaa aaggtacatt
    11341 ttttaacata taatttgata taatgggatg ttttgccaat tcatttttgg gatttgtaac
    11401 taagtacaat tctgttttat agattgtctt tgaatctata tcatcataaa tatcactgtc
    11461 aattatacca atacaaaaat caagtgtaga ttcttcaatc attttagctc caacaaatgt
    11521 tggaacttca aaaattttaa gctctatatc tggataaatt acattaaatc taggaagtat
    11581 ttttgaaagc aaaaacgtac ctaaaactgt aggaatacct attttgagag aagcttttct
    11641 cttttttcct aaatcaagtg cgtcacattg aaaatcctca aattgtttta taaaatgttt
    11701 tgacttgtct aaaaaaattt ttccttcagg cgttaattct attttattac ctattctgta
    11761 aaaaagttca aagccaagtt ctttttctaa ttctttaatt gctaatgtta tggatggttg
    11821 agaaatatga atactttccg cagccttagt catgttttta tatttacaga cagtttgaaa
    11881 atagtataaa tagtttatat tcatttggta ttagttcctt tcatttacat attagtgaca
    11941 agtatataat taacaatagc ataagttttg tatattgttg taaaaaaata gaatagtttt
    12001 aaactatcat agcataagtt tttgatattt tcaatctatt aagaatagtg ctattattaa
    12061 attaacaaaa gagaatagct ggtatggttt agagtaaatc aatctatatt acagttatat
    12121 caacgaatat caaaaaatta tctattagaa aataaaaatt a
//
LOCUS       DAEQJM010000094        11966 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.095, whole genome shotgun sequence.
ACCESSION   DAEQJM010000094 DAEQJM010000000
VERSION     DAEQJM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11966
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.095"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            323..1363
                     /locus_tag="KRQ43_003305"
     CDS             323..1363
                     /locus_tag="KRQ43_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH2743645.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            1719..3041
                     /locus_tag="KRQ43_003306"
     CDS             1719..3041
                     /locus_tag="KRQ43_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH2743646.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            3339..4700
                     /locus_tag="KRQ43_003307"
     CDS             3339..4700
                     /locus_tag="KRQ43_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH2743647.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            4773..6167
                     /locus_tag="KRQ43_003308"
     CDS             4773..6167
                     /locus_tag="KRQ43_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2743648.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQLAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            6229..6699
                     /locus_tag="KRQ43_003309"
     CDS             6229..6699
                     /locus_tag="KRQ43_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HBH2743649.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIKEAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            6702..8918
                     /locus_tag="KRQ43_003310"
     CDS             6702..8918
                     /locus_tag="KRQ43_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH2743650.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHNIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFRGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLIVEEAEKLLETSKEDLYLDNGYVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGLTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVNSYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            9001..9672
                     /locus_tag="KRQ43_003311"
     CDS             9001..9672
                     /locus_tag="KRQ43_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH2743651.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            10035..11249
                     /gene="dpaL"
                     /locus_tag="KRQ43_003312"
     CDS             10035..11249
                     /gene="dpaL"
                     /locus_tag="KRQ43_003312"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH2743652.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            11376..>11966
                     /locus_tag="KRQ43_003313"
     CDS             11376..>11966
                     /locus_tag="KRQ43_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH2743653.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKG"
BASE COUNT         4543 a         1358 c         2404 g         3661 t
ORIGIN      
        1 aagaatttta aaatttataa aagtaatttt atataggtat aaaaattacg agtagtataa
       61 aaaatttaat aagaacttaa attaaaaatt ttaaaaatta ttttcatata aaatatggca
      121 ttgtaattgc ttatttaata gaggattttt gtaaaatgaa gaaagtatat ctatcaaatt
      181 aaaactaagt agatatactt tttattaagt tttgttttaa aataatatta ttaaattata
      241 actaagcttt tctgttatga tataattaaa tagataatgt gaatgattat tatatagaat
      301 acttatttgg agttgatatt ttatggacaa acacagtgat tcagtaatgt atggtggaat
      361 ggaagtatat aatatttggg gaacaacaac agtagactcc ataattggag agtctgatgt
      421 aatgcgtgct cttaagaata gaatttgcaa aattggaaat agtgattcta ctgtagctat
      481 aactggagaa agtggcactg gaaaagaatt aatagcaaga gccattcatc tcgcaggaaa
      541 cagagggaat aaaacattcg ttgctataaa ctgtgctgct ataccagaac ctttactaga
      601 aagtgaactt tttggatata caaaaggagc ttttagtgga gcagattcaa aaggtaaaat
      661 tggtaagttt gaattggcca atggaggggt tgtattttta gatgagatag gagatatgcc
      721 aattcaacta caatcaaagt tattgagggt attacaggaa aagaagttta cgagaatagg
      781 ttcaaatgaa ctaattgata tagatgttag aatcatatca gctactaata gagatttatt
      841 tgagttggtt aaggaaaata aatttagaga agacttatac tatagattga atgtaatacc
      901 tttagaagtg cctccactta gagaaagagg agacgatata caaatattaa taaataattt
      961 tatagacaaa tattcgagaa aaatgaagaa aaacgtgtac catatagaac cagatgtgga
     1021 acaaatgttg cttaagtatc cttggccagg aaatattaga gagttggaaa atactataga
     1081 actggcatta aaccttcttg aggaagatgg aataatacat aaaggaataa taaatagaaa
     1141 gatacttgaa tattttaagt taaataatat aaatataaag ttacttgagg aaagtgacta
     1201 tgagataagt atggaacaag acatacttac acttgaagag tttgaaagag cctatataaa
     1261 gaaagtgtta aagttttacg gaaatgatac taagtctaaa aaactggctg ccaaaaaact
     1321 tggaatatca ctagctacat tgtacagaaa aatagatgta taataattag gttttttatt
     1381 ctcaattcta aaatttgaaa ttataaaatt gataaaaaac acttggaaaa ctattttcta
     1441 agtgtttttt tgtgtaatag cattttatta tccaaaaata aaaaaaattt aaaagaattt
     1501 aaaaaaataa atgctttaat aaattatcaa atactaacaa atataataaa aattatatat
     1561 gtaaaacaat tatgttaaaa aattggcatt ataattgctt catattaaat tgagatgaca
     1621 aaataaaaaa agaaaggatg ttgtgtgaga taataataac tgtcattaaa aaatagttgg
     1681 gagtgataac cttgagtaaa tatcaaaaga atgtttctat gtttgatatt gatggaaggc
     1741 caccaatttt aaagtgtttg ccactatcaa tgcaacatat actagcaatg atagttggaa
     1801 ctgttacagt acctatagtc gtaggaggag ctgtgggtgt tagccctaca caaataacac
     1861 ttttagtgca atatgcatta ataatagctg gtatatcaac acttatacaa ctatatccaa
     1921 taggaaatat tggttcaaga ttgcctataa tttttggagt tggttttact tatgtaccaa
     1981 cacttgtagc agtcggagga aattatggat tagcaagcat tttgggtgca caattaatag
     2041 ggggagtggc tacagtatta atagggatat tcataaaaaa gataagaaaa ttttttccga
     2101 atatagttgc aggaacagtg gtttttacaa ttggattatc tttgtatcct atagcaataa
     2161 attatatggc aggtggtgta aatagtccta cttatgcctc tatgcaaaac tgggcagtag
     2221 cggctataac attagtggta gttataggtc ttagtcaatt tgcaaaagga tatgcaaaat
     2281 tggcagcaat atttttggga attatagttg gatattgtgt atctttagtt ctgggtataa
     2341 taaattttga ccctattaga gaggcaactt ggtttgcgat acctaaaccg cttgaatttg
     2401 ggatggaatt tgatatgcct gtaataatct cagtagtaat tgtaagtata atcaatgctg
     2461 ttcaagcaat tggagattta tcagctacta caatgggagg catggatagg aatatcacag
     2521 ataaggaatt atcaagtgga gtaataggaa gtggaatttg tactatgata ggagctttgt
     2581 ttggaggttt accaccatca tcatatagcc aaaacgtggg gatggtagct atgaacaaag
     2641 taataagtag atttgtgctt ggaatagctg gtatatttat gttattgtcg gggtttgtgc
     2701 ctaaatttgg tgcattaatg actactatac catattctgt tttaggagga gctacaatat
     2761 ctatatttag tatgataaca atgacaggta taaagttaat tattacagaa gagttgtcat
     2821 caagaaatat taccattgtt ggtttggcaa ttgccttagg catgggaata acatcagtac
     2881 cagcagccca agaggcattt ccttcatttg taaagttagt atttggagaa tctccaatag
     2941 taattgcaac attggttgca ttcgttttaa atctaataat accaaataaa agtctagagg
     3001 atgaggctaa agaaagagct gttatggaag agactaatta agatataata atttaaaaga
     3061 attgtttaaa ttatttagta tgagattgtt agattatttt tgatagctat tcattttaat
     3121 aaaaaattta acaaataaat atataccagg caattaatgt ttcatttaag ttgaaaatcg
     3181 gggagggaat atttagaaat ttgttaattt tttataaaaa tagctcagtt tagctgtgtt
     3241 tatcggttga gcaataaatt catggtcata aaaatattta tagaaaataa ttataaaaat
     3301 atttagtcaa gatatttatg tatgggagga tttattttat gaaaacacgt aatacttcaa
     3361 aatatgatgt cgatgggata ccaccactaa aggaatcaat acctttggcc ttacaacatc
     3421 tgttagcaat gatagtagga aatatggtac ctgcgatatt aatagcaaac gtggtaggac
     3481 ttaaccaggg gcaagcaaca atgttgattc agggttctat gttagcagca ggtttagcaa
     3541 cgtttttaca gttatatcca atacctttat ttaaaggatt taagttaggt tcaagattac
     3601 ctgtaatgat gggaatgagt tatgtatttt taggagcttg tctttcagta gcagctaaag
     3661 atggtttagc agctctattt ggagcacaga ttgctgctgg ggtaatcgta ttctttgtag
     3721 gatttggagt taagaaaatt agacatatat tcactccaat agtttctgga actataatag
     3781 catgtatggg acttggacta ttcgcaacag ctataaagaa tttagctgga ggagaaggca
     3841 cacaaacatt tggaagccca ataaacttca cagtaggagt tatagttgct tttgtaataa
     3901 taatgataaa taaatacggt aaaggtttag taaaaaattc ttcaatatta ataggaatat
     3961 tagtaggtta tgctatatct ttagttttag gattggttga tttctcagcc gttcaaggag
     4021 cagctatagt atctttacca acaccagcag cttttggatt agaatttaga ccagagttaa
     4081 tagtaatgtt tactattatt tacataatag gtatagctga tatgatgggt gcctgtacaa
     4141 tagctacagt aggagcaatg gatagagagg taactgacga agaattagca tcagttgttt
     4201 taggaaattc tataacttct ataatttcat cactatttgc agctcttcca actggagtat
     4261 ttagccaaaa tacagtaatt gtatctatga acaaagttac aagtagattt gtaatagcac
     4321 taggggcact tgtattatta ctagcaggga tatctccagc attgggtgca ataatgacaa
     4381 ctataccatc ttgtgttgtt ggtggagcaa ctttagtagt tttctcatca atagcaatgt
     4441 ctggtttctc tattatgagt atggatggat tcactgaaga aaacaatctt atagcaggtg
     4501 tatctatagc aacaagtatg ggtcttacaa ctgctccaca agttttagac caattcccag
     4561 aaacaattgg aactgtcctt ggagggtcaa gtatagtttc tggagcaata atagctatat
     4621 tacttcaaac attatttaaa ttaaagtcac gtaaaagtgc tgaaaacgtt acttcaaatc
     4681 ttgaggaaaa tattggataa atgtattaga tataatatga gaaaaccata tggtaaaatg
     4741 ttgtaatgaa agtattcaaa gggggattta agatgattga tatactaata aaaaatgcaa
     4801 taattgttac agttaataaa gacagagatg ttatatttga tggagcaata gctattcaag
     4861 gtgacagaat cttggatata ggaaatacag ttgatattga gcctaagtat cttgatgcta
     4921 aaaaagttat agatgctaat ggaaaagtaa tattccctgg ctttataaat actcataatc
     4981 acctgttcca agtgttatta aaaggtttag gtgatgatat ggcacttcat gagtggttaa
     5041 atacaatgat gtttccatca gcaaaattct taacagaaca agatacttat gatgctgcaa
     5101 tgcttggatg tatggaaggt ttaaaaagtg gtataactac aatggttgat tatatgcata
     5161 ctcacaatag accaggactt acagatggaa tagtaaaggc atataaagat ttaggtataa
     5221 gaggggttgt aggtagaggt tgtatagatt taggtattca caaagagctt atagaagatg
     5281 tggaaacggt tgaaaaagat ttgagaaggg tattcgaaaa atatcataat tcagaaaatg
     5341 gaagaataaa aatctgtgta gctccttctt caatgtgggc tatatctgaa gaaatgggta
     5401 agatgctttg gaatatagtt aaagaatatg attcatattt tacagttcat atatctgaaa
     5461 cagaatttgc aagaacagca acaaaggata tacatggaga aatagatata aaattacttg
     5521 aaaaatgggg tatagtaggt ccagaagttg tagcagtaca ttgtgtatgt ataactgatg
     5581 aagacatgga aatgcttaaa aagtatgaca taaaagtttc tcataatgta gcaagtaata
     5641 tgtatcttgc ttctggtgtt gcacctgtgc cagaaatgtt aaaaaaaggt ataaatgtga
     5701 gtttaggtct tgacggtgca gcaagtaata acgcacaaga tatggtagag cttatgaaat
     5761 taacagcttt acaacacaaa gtaaataatt gtgaccctct ggcaatttct gcagagaaag
     5821 ttcttgaaat ggctacaatt gagggagcaa gaactcttag aatggaagat gaaataggtt
     5881 ctttggagat tgggaaaaaa gctgacctag taatatttaa ctcaatgctt tctccaaaat
     5941 caatacctct tcacaatcct gtatcaactt tggtatactc agctagtatg cacaatgtag
     6001 agagtgtttt agttgatgga aatgtaatac ttgaaaatgg aaaagtaact acaattgaaa
     6061 gtgaagaaca agtgttgctt aatgcacaac ttgcagcaga agaattatgt aagagagcta
     6121 atgtaactaa tagaatggaa ggacataagt ggaatagctt atactaatat taaaataaga
     6181 ttgtaataat attctattac aacattagtt tatctgtagg aggagaaaat ggaaaaaata
     6241 aaattaaata ttaatgatta catgtatgaa atagaagttg aaaagaatga aactcttttg
     6301 catgtacttc gtgaaaaatt aaatctaact ggagcgaaac aaggttgtaa tagtggcagt
     6361 tgtggagcat gtaaagtttt gatagatgga gttgacatga aatcttgtaa acttcttgca
     6421 aaaaactgcg aaggtaaagt tatatacact atagaaagtt ttgctaatgg agaaaatctt
     6481 catccaatac aagaagcttt tatagaagtt ggagctgtac aatgtggata ttgtactcct
     6541 ggtatgatta taacaacaca agctctttta aatagaaatg catctcctaa tgaagatgaa
     6601 attaaagaag cttttaaaga aaatctctgt agatgcacag gatatgtaaa gattatagaa
     6661 gctgtaaaat tatctgcagc tagattaggg ggtagataat tatggaaaag gtaataggaa
     6721 aatcataccc tctaaaagat gcagctttaa aagttactgg tcaaatgaaa tacgtggctg
     6781 atatgaaacc acaaaatgta ctttacgcta agatgctttt aagtcctgta gcacatgcaa
     6841 aaataaaaag tatagataca agtgaagctg agaaagtagt aggtgttaga gctatagcta
     6901 cttatctcaa tacatcacaa agaaaataca atggttcatt aagattttat gagcacaata
     6961 tacctgaaaa tgaagttata ttttcagata cagttagatt tgttggtgac cgtgttgcag
     7021 cagtagctgc agagactcca gaaatagcag agaaagctgt aaaacttata aaagttgaat
     7081 atgaagaatt gccagctgta tttactatac aagatgcaat aaaagaagat gctatctgca
     7141 tacatggaga ttcaaatata gtttctcaaa acaacataaa tgggggagat gtagaaaaag
     7201 gcttcaagga atgtgactat atatttgaag atgaatactc tactccagca atacatcata
     7261 gtgcaataga gactcatagt gtaattgcac actatgatta taatgataaa ttaactgtac
     7321 atacaccttg ccaaaataca tttggattta gaataatact atctcaaatt tttgggatgt
     7381 cattaaataa agtaagagtt ataagacctg ctattggagg ctcatttggt ggaaaattag
     7441 aacttacaat tgaaccagta gcagccgcat tatcaaaaat gacaagaaga ccagttaaaa
     7501 tggttcttac aagaaaggaa tctatgatat caacaagaac tcgtcatggg tcttttgtaa
     7561 aattaaaaac tggtgtaaat aaagatggtg aagtaatagc acaagatata aaaatatata
     7621 caaatacagg agcatatgca tcaagtgctt taaatgttat aggagcactt agtcataaag
     7681 tatttaaagt ttataaaata ccaaatataa agtttactgg gatgcctgta tatacaaata
     7741 caccaatagc aggagctatg agaggctatg ggtcacctca aatatttatg gctcaacagg
     7801 ctcaatttgc gaaaatagcc aaggaaatag gtatggattt agtcgatttt caaaataaaa
     7861 atgcagtaga gccagatgat gtcgatataa tcttccgcgg ttctcttgga aatcctagag
     7921 tattggattg tatagagcaa ggtaagaaga tgtttaagtg ggatgaaaag aaaaaacttc
     7981 caaaagaaga aggaaaatat ttaagaggta taggtatggc aataggtgca catggtaatg
     8041 gagtttttgg tgcacataga gatgttgtta cattgactct taaattaaat gaagatggta
     8101 cattgacact actaacagga gcacatgata tgggtaatgg tgtcgtaact atgcaaacaa
     8161 tgatggtagc tgaagtttta ggaataacac ctgataaagt tgatacattt gaaactgata
     8221 cggatgcatg tacattcaac cttggtgact atgcaagtag aggggtattt gtagaaggtg
     8281 gaggagctaa aaagacagca gagaaattga aaaaccttat agtagaagaa gcagaaaaat
     8341 tacttgaaac atcaaaagaa gatttatatc tagacaatgg atatgtaatt agtaaacttg
     8401 atgaaaatgt aaaagcatca ctttctgatg tcgcagtata tagtcaaagt aaatcattaa
     8461 gagagttaac tgttgttgaa gattattctt caccagctgg acttacttct tatggtgtac
     8521 attttgctga agttttagta gataaagaaa ctaaggatat aaaagtagtt gattttgtag
     8581 ctgtacatga tgttggtaga gttataaatc ctttaaattt agaaggtcaa ttagaaggtg
     8641 ggattcatat gggtctagga tacgcattga gtgaagaatt ggcatttgat gaacaaggta
     8701 gacctaaagc tactgatttt aaaacatata aattatttag aactgtagat atgccaaaat
     8761 gtcaagttgc atttgtaaat agttatgaaa aagctggacc ttttggtggt aagagtattg
     8821 gagaatgtgc tgttgtacca gttgcgccag ctgttgcaaa tgcagtatat aatgcaactg
     8881 atgtagaaat acattcattg ccaataaaat taaaatagta gaaattaaag cacaaacaac
     8941 aatttattgt atttgtaaat agataataaa aatagattta tttggtgagg agatattatt
     9001 atggcaaaga tattaggtat ttgtggaagt ccacgtaaag gagcaacaga atatgcagtg
     9061 ttagaagctt tgaaagaagc agaaactata cctggtatag aaactgagta ttggtcagtt
     9121 agagggaaaa aaataagtcc ttgtgtacat tgtgatgcat gtataagaaa agaaactatg
     9181 tgtattataa aagatgatat ccaagaatta gagcaaaaaa tattggaggc agatggaatt
     9241 atagtaggtt ctccagttta tgatatgaat ataactgctc aacttacagc agtatttaat
     9301 agacttcgtc caatgtattt agttcatcca ggaaaacttc aaaataaggt tggtgcagct
     9361 ataactactg gtggaactag atatggtggc caagaattga caaaacttcc tataataaat
     9421 ttcttcctaa tgcatgaaat gttagtatct ggaggtttag gtggatgcta tataggtggt
     9481 acaatatgga gtaaagatgg aaaagcaaaa ggtgcccaag aggatgagac aggtatggac
     9541 acagtaaaaa gacttggaaa aggtgctgca gaggcagtta tggtttctaa gtttggtctt
     9601 gaaaaatgga atgtcgtaaa agaagaatta gatgttaaaa aagatgaaaa atcacctctt
     9661 agagaccact aaagatttat tatattatta aatatataca aatagtgatg taatagatta
     9721 ttgcatcact attttatgtt ttaatttaga ttttataaat tttatattaa aaaatataga
     9781 aacaaagtgt tttgagattt atttttaaat tttaaaaatg agaattaaaa agtgagaaga
     9841 tagaaaaggt tttttagtta ttaaattcta catacattgt atgaactaaa gatagaaaag
     9901 aaagaataat aaaagcattg caatttctat actaaagagt catagaaaaa tatctagtat
     9961 atatttagtg ttggcatgtt aattgcttat atattaaagt ataaaaattt aacaataatt
    10021 tggaggtatt ttagatgtta aaagaaatta aatggaaagt aaataatttg ccaaagggtg
    10081 ataaggaaaa ttgtatcaaa tttttaaatg aagaagaaat aactaaggtt agaaattttc
    10141 acaaaagctt tcctcaatat aaagaaactc cattagcaaa cctagaaggt ttagcaaaaa
    10201 aattaggtgt tgcaggagta tatgtaaaag atgaatctta tagatttgga ttaaatgcat
    10261 ttaaagtatt aggtggttct tattctatgg gtagatactt agctcaaaga ttagatacag
    10321 atatatctga gttagggtat gacaaattaa cttcgaaaga aataaaagaa aaattaggag
    10381 aaataacttt ctttacagct acagatggaa atcacggtag aggagttgct tggacagcta
    10441 ataaattagg tcaaaaatct gttgtattaa tgccaaaagg ttcttctgag tttagattaa
    10501 ataaaattaa aggagaagga gcagatgcta gtataacaga cttaaactat gatgatgcag
    10561 taagattagc taatgattat gcagaagctg atgatcatgg agtaatggtt caagatacag
    10621 catgggatgg atatgaagaa attccagcat ggataatgca aggatatgga actatggctc
    10681 aagaagcgat agagcaatta aaagaatatg gagtagatag accaacacat gtatttgtgc
    10741 aagcaggggt tggttcactt gctggagcag ttcaaggata tgttgcttca atatacgatg
    10801 aatgcccaat aacagtagta gtagaagctg atgaagctga ttgctactat aaatcagcag
    10861 aagcaggaga tggaaaacca agatttgttg gaggagatat gccaactata atggctggtc
    10921 ttgcttgtgg agaaccaaat actataggat ttgaagtatt aaaaaatcat gctgcagcat
    10981 ttgtttcagc accagactgg gtttctgcta aaggtatgag aacattaggt aatcctttaa
    11041 atggtgatga aaaggtaatt tctggagaat ctggagcagt tacaactggt cttttagtag
    11101 cagctatgga aagagaagat ttagcagatt taagaaaaga tttaaaatta gatgaaaatt
    11161 caagaatact tttaataagc acagaaggag atactgaccc tgacaaatat agaagtatag
    11221 tttgggatgg agaatatcca agtatataag gaattactaa aatgcaatta ttagatattg
    11281 gtttacatat ttagaagata tataagttct aaaatttaga aaatatataa gtatataaaa
    11341 tacatacatt ataaaaaatc tagggggata atgaaatgtt aaacgaacaa agaaaacaag
    11401 aagtaactga aatatgccaa aaattaattc aaaatcctag ttcttctgga aatgaagaag
    11461 gtgttgtaaa agcaatagaa gagtcttttg aaaaattagg ttttgatagt tggtcaagag
    11521 atagatatgg aaatatagta ggatgtataa aaggtaacaa gccaggtaag aaaatattat
    11581 ttgatggaca tatagataca gttccagttc cagatgcaag taaatggagt gttcctcctt
    11641 ttgaaggaaa aatagttgat ggaaagatat atggtagagg aacttctgac atgaaaggtc
    11701 aatatactgc aatgatgtct gctgtagcgt attttgctaa agacactaat cgagattttg
    11761 ctggagaact atatgtagca ggtgttgttc atgaagaaat atttgaaggt gtttcggcta
    11821 gagagataag taaggctgtt caacctgact atgttgtaat aggtgagtct tcagagttaa
    11881 acttaaagat tggtcagaga ggtagaggag aaatagtagt agaaactttt ggtaaaccag
    11941 ctcactctgc taatccagaa aaaggt
//
LOCUS       DAEQJM010000095        11621 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.096, whole genome shotgun sequence.
ACCESSION   DAEQJM010000095 DAEQJM010000000
VERSION     DAEQJM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11621
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.096"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(514..1251)
                     /locus_tag="KRQ43_003314"
     CDS             complement(514..1251)
                     /locus_tag="KRQ43_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743654.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            complement(1263..2024)
                     /locus_tag="KRQ43_003315"
     CDS             complement(1263..2024)
                     /locus_tag="KRQ43_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743655.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPILMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            complement(2024..2947)
                     /locus_tag="KRQ43_003316"
     CDS             complement(2024..2947)
                     /locus_tag="KRQ43_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743656.1"
                     /translation="MKHMEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGA
                     GKSTTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENM
                     TIMQRLLDLPKKNVNEALKIVRLENQKNKKVNQYSLGMKQRLGIAMAIMKFPKLLILD
                     EPTNGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQD
                     SIKELHNRGQSQIAIKAKNVVSAQKLLNTKGYMSLIQNGYLTIENLKDSDVAKINGML
                     VHSNIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            3109..3816
                     /locus_tag="KRQ43_003317"
     CDS             3109..3816
                     /locus_tag="KRQ43_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743657.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            3861..5267
                     /locus_tag="KRQ43_003318"
     CDS             3861..5267
                     /locus_tag="KRQ43_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2743658.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILKDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTIKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGVKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVAGIINAHRGKLDI
                     MSIDSQGLKTILKLPLIK"
     gene            6856..7245
                     /locus_tag="KRQ43_003319"
     CDS             6856..7245
                     /locus_tag="KRQ43_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH2743659.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
     gene            7990..8460
                     /locus_tag="KRQ43_003320"
     CDS             7990..8460
                     /locus_tag="KRQ43_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH2743660.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIEFVKQCENSKE"
     gene            8753..9622
                     /locus_tag="KRQ43_003321"
                     /pseudo
     CDS             8753..9622
                     /locus_tag="KRQ43_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
     gene            10528..11235
                     /locus_tag="KRQ43_003322"
     CDS             10528..11235
                     /locus_tag="KRQ43_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH2743661.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
BASE COUNT         4655 a         1160 c         1830 g         3976 t
ORIGIN      
        1 atagattact ttaaatccct ttgaatattc tataacacta taaattactt ttaactttta
       61 tataaccata aagtttttat ctggcacttt aaatggagtt tttatatcaa atttgccttc
      121 catcgaataa ccaaacttaa tttaattaca cattccaaga gtcaaatatt cattcaatat
      181 atttgataat tctatgttat agccataatt aaatatagat tattaaagtt aaatatttat
      241 ttaatgtatt gaatgatttt ttagctatat ttaattaagt ttcattatat aatataaaaa
      301 ttgtttttgc attaagtttt aatataacac ataataattt taaataataa cattattata
      361 tattttttta ttttaggagt atatctatta tatagtgagt agataaaaca tataaaattc
      421 aaataaaaga tatatatttt taaataaaag ggatataaat ttcaaaccaa aaagaatata
      481 aatttcaaac caaaaaatat ctagcattta ccattaagaa ataacatcat tctttctaaa
      541 atttctattg gcaatttcag aaaatactat agtagtaata aatgcaacac atattgtaac
      601 tatagtgtca ttaacattta aagcagattg ctttataacc cccatagcac tacctaacat
      661 agaataaggg aaaaatatac caacagcagg ttttgctact attaatccca taccaaatag
      721 agaaaggcaa agactaatac caataggagt tgcaaaactt ctaatcttta tagacatgta
      781 taattgtata gaagctattg aaatagaaat aatccaacct ttagcaatcc aaccagtcaa
      841 ttctttaggt acactaccag aaaaaccaaa catatttcct gcaactatat aaaagataac
      901 aaagaaaact tgtgtaatag ctgtaagtat tgaaactact gtaagtttag ataaaaagat
      961 attttttaaa ttaactggca gtgtcattac attattccaa ttatgattca tatgttcaag
     1021 cctacaaata tatgcacaaa agattgcgat taagatagga aagaaaaatt ccccataaaa
     1081 aagactaact tgagtccata agctgtacca ttcttttttg agtatgcctt gatttagata
     1141 aaaattacca gaaccaatca acacacttat aagtggcaaa gctaataata cataccatat
     1201 aaaagaattt tttaacttta gaatttctcc caaaactgac ttccttaaca tttaaatccc
     1261 tcctatactt ctttttttaa taaatgattt cttccaatat aataaattag cattccaatt
     1321 aagaaaacta aaatcgtaat agaaaaattc atatcaattc tatagacaga tgaacctaaa
     1381 acattatcat aagcataact taaaggtgat aactctaggt aataagacca tataaacaat
     1441 ctacgaatac cttgataaaa caaacctgat gtcaaaccta taaaactacc aatcatgcca
     1501 aatgtaattg caatcatttg atttggaatt acagttgcaa tccataggtg tagtgcaatg
     1561 atagcaatac ttacaagaat tgttcctaat gtgtatttta aaagtaaaga tacagaaatt
     1621 gactcaataa cccctctaaa atgtccaaac aacacaatag ataacacttg catcaatata
     1681 ggtatagata ccaaaatagc agaacataaa aatttggata aataaatact atttaaagat
     1741 gtcacagaag attttaaaag cttccatgta tctcctttat gttctatatc gcttatgcgt
     1801 gatgtaatta ttgatattaa gataggaaag aatagaccat ttaaacttgc aaaactcata
     1861 agcatatagg aatattcaaa tccacctaac atatctggat tacgtgtaat agccctattt
     1921 gaatttacga tacaccacat tatttcaaca gctacaaata aaaaggtcat cagaataatc
     1981 ttctttcttt taagtttata aaattctaga ccaaggtatt tcattataaa gtcaccgcct
     2041 taccagtaag ttctaggaat atatcttcca agcttttttt atgttcttct attctaaata
     2101 catctatatt tgaatggaca agcataccat ttattttagc cacatctgag tcttttaaat
     2161 tttcaatagt caagtaccca ttttgtataa gtgacatata tcctttagta tttaatagct
     2221 tttgtgcaga tacaacattc ttagctttga tagcaatctg actttgacct ctattatgaa
     2281 gttcttttat gctatcttga aaaaccagtt cgccatgatt tattattcct attgatgtgg
     2341 caatttggtc aatttcactt aaaagatggc tagagattag aacagtcatg ccgtattttt
     2401 ctggtagaga ttttattaat tctctaattt cctcaatccc tgctgggtcg agtccatttg
     2461 taggttcatc aagtattaat aatttgggaa acttcattat tgccatagca atgccaagac
     2521 gttgcttcat acctaaagaa tattgattaa cttttttatt tttttgattt tctaacctta
     2581 caatttttaa tgcttcattt acattttttt taggtaaatc taagagtctt tgcattatgg
     2641 tcatgttttc aagccctgta agatgaccat agtatgatgg agattctatc aaagaaccta
     2701 tatcttttaa aattgatatt ctattttttt catttaactc tttacctaaa atattaatat
     2761 ttccttgtgt gggtttagca agtccaagaa gcattttaag agtggtagat tttccagctc
     2821 cattaggacc caaaaaacca tatacagctc cttgtggaac tcttaggtct atatccttta
     2881 ctctaaatat tttattgtat tcctttgaaa gtctttgtgt tctaattatc atttccatat
     2941 gtttcatccc cttttttaat ctgtgcttat tgattctttt aacttatatc agtataataa
     3001 cttggttaca tttcagttag ctgaagttta ccttacaata accttaaaag tctatttagg
     3061 caaagttgtg aaaatgggta tatggtatac taaaggaggg tgatgattat ggagtcaata
     3121 aaagataaaa aaatacttgt ggttgatgac cacaaggaat tattaaaaat gatagatgaa
     3181 atcctaagaa aagagggatt tagtagagta tttttagcat caagttatga agaagctgtt
     3241 agggtattta gaaatgtaaa gccagattgt gcaattttag atgttgtatt gccagatgga
     3301 gatggtttct ctattatgag aaaaattaga gagacatcta agataccagt tatttttctc
     3361 tctgcaagag gtgaagatga agatagattg attggtttgg gattaggggc tgacgattat
     3421 atagtaaagc catttttacc aaaggaactt actttaaggc ttgtgggtat attaaatcgt
     3481 gtatatgtgc ctatagaaga agaggagttg ccagtattta aactgggaga ttctgttgtt
     3541 gtgaatttaa atagtgcatg tgttgagaaa gatgggcaag agatttcttt aacagctaaa
     3601 gagcattcgt tgcttttaaa gttgtatgaa aataaaggga gaattgttac taatgattca
     3661 ctatgtcaag ccatttgggg agatgatatg tatggatatg aaaataccct tatggttcat
     3721 gttagaaggg ttagagagaa gatagaaaaa actccatcta cacctaaaca tcttattaca
     3781 gtaagaggtc ttggatataa gttgatgatt aattaatttt agatattaga ataaaagaaa
     3841 tcaagaggag tgatttaatt ttggatagtg taaagtacat attgaggcga tttataggtt
     3901 caagtatctt gatttcatta ctttttattg tattaaatat agcaggtttt cttctgtttt
     3961 catatatgct atttgtatct aaatactctg ataatttaga tacaagtgat agcagagaaa
     4021 taaaatcaaa cttgattatg attgaagata atttgatttt aaaagatgga aagtttattt
     4081 tagatgattc tagtaaggaa gtactacata aaaataaagt ttgggcaatg ttaattgata
     4141 acaatggaga tagaatatgg ggatttgatt taccaaaaga aattccaagt cattatactt
     4201 tgacagatgt agcaaagttt tcaaggttct ttttaaagga ctatcctgtg tatgtatggg
     4261 aacatccaaa tggaatatta gtaacaggtt atccaaagga caaatacact aaatttaacc
     4321 ttacttatac gattaaggaa atagaacaat ttcctatgtt aataataggt atgtttctgg
     4381 ttaatgcaat agttactttt ttaatagctc tattcatagg tttaaaaatg gtgaaatcta
     4441 taaaaccaat tattactggc ataaagctta tgtcaaaagg agaaccagta cttttacaag
     4501 aaaaaggaat actaagtgat atttcaaaat ctattaatac tgtatctaaa gagttgcaaa
     4561 tgaaagatga aaaacttagg aagaaagagg aagctaggtc taactggatt gcaggaatat
     4621 ctcatgatat aagaactcca ctttcaatga taattggata tgctggagaa cttgaagaaa
     4681 gcagtagcct ttcaaataga gaacaagagc aagtgtctat tatatgcaat caaggggtta
     4741 aaatcagaga attagtaaat gacctaaatt tagtatctaa acttgaatat aatatgcaag
     4801 cattgaattg tgataagatt agagtttctg cgtttttgag agagcttatt tctgagttta
     4861 taaataataa tttggataat gacttttatg ttgaacttga tatactaaat gaagatatta
     4921 ttatagatgc agataaaaaa ttattaaaaa gggctattag taatttaata caaaatagta
     4981 taactcataa ccaacaagga tgtaatataa gggttacctc taagtctgat ttagattttt
     5041 gctatataat tgttgaagat gatggaaaag gtatgagtca agaaagaatt aatagtttat
     5101 taaagagcca aaatggacta agtgaggcat atgccaaagg tcaaaatcat ggtctaggta
     5161 ttttgatagt agctggaatt attaatgcac atagaggtaa attagatatt atgagtattg
     5221 atagtcaggg actaaaaaca atactaaaat tacctctaat taagtgatat tttataaaat
     5281 aataacagat aagaatgaag aatgaagaat gaaaatattt tgaaaataat tttattcttt
     5341 attgacaaaa taactctatt agagtagaat aaggataaat tcttttcttg tcaagtttta
     5401 ttaaagtaaa gagtaacttg tgctttatgc gcttatggct gagttactca tggtatcaaa
     5461 attttcatag aaataatatt ttggaattat tgtaaggtta ttaaattctt tagataattc
     5521 catttttttt attttttagt taatatttaa ttttattatt gacaaaaaaa ttctactaaa
     5581 atagaattat ggtatagtgt tttttaattt taagaaaaaa tataatgaca tcctaaaaaa
     5641 gttttaatta tacgttgttc tgtgtagtta taatagcttc tatgtaacta ttgtaagtat
     5701 attttattat aattatttat ttaaagtacg ataaatgttt taaattgaag tattttgcac
     5761 cattgagttc tactaaagta gagtttttgt gtagtatttt tagaaataac atatatatat
     5821 atgtatttat gttgaaatat atgggaaatt tataatataa ttaatgaaaa aatttaaatt
     5881 ttgtaatata taaataaaaa aactctaaaa tagaaggata taattatata gaatgtttca
     5941 attaaacaag gcaaaaacta taatcttaaa attaaaatta acattattct taagaagtaa
     6001 gaaatttaag aagtaaaaag tttagtgata agtggtagta agcaagaaat ttagaaagta
     6061 ggaagtttag tgataagtgg tagtaagcga gaaatttaga aagtgggaag tttagtaata
     6121 atttgtagca agtaagaaat ttaggaagta ggaagtttag taataatttg tagcaagtaa
     6181 gaaatttagg gagtaggaag tttagtagta ataatttgta gcaagtaaga aatttaggga
     6241 gtaggaagtt tagtaataat ttgtagtaag taagaaattt agaaagtagg aaatttagta
     6301 ataatttata gtaagtaaga aatttagaaa gtaggaagtt tagtaataat ttatagcaag
     6361 taagaaattt agaaagtagg aagtttagta gtaatttata gtaagtaaga aatttagtaa
     6421 gtgagaagtt tagttataat ttatagtaag taagaaattt agtaagtgag aagttcagta
     6481 ataagttgta gtaaatgaaa agtttaggaa gtaggaagtt cagtaataag ttgtagtaaa
     6541 taaaaaattt aggaagtagg atttactgaa atacaaatat ttaaaatcaa agagtttaaa
     6601 agaaaggaga gctactggac aagtatccaa aatagatagc tgagtacaaa atatctcata
     6661 aaattaagca atataataca agagaatttt gacattattt atatatattt accgtgtaca
     6721 aatagctaaa tttaggatta agattgaaaa atatcttata agtctgagct tatataaatc
     6781 cgtataagat gtatttaatc gaaaaatttt attatggata ttgcttgtct atattctgag
     6841 tagcaaggtt ttatcatgac tataaaaaag ttgccacaat cagaattaaa gataatgaaa
     6901 tttatatgga aatcagattc caaagtaaca tctagagata ttgttttagg aatggagcaa
     6961 aaatatcaat ggaaacaaac gacaactttg actcttttat ctagattagt agtaaaaaga
     7021 tttctaaatt ctcaaaagat agataaatat acacattatg aagttttaat taaagaaaag
     7081 gaatacatag gagttgagac aagagatttt tttagaaata ttcatgattc ttctataaaa
     7141 agtttattgt tgtcattaca tgaaaatatt aatttgagca aagatgatat cttacttatt
     7201 gaagagtgga taaaaaatct aaaagaagag gagaaagacg tataagcaaa cgtatttctt
     7261 atagcattaa tataaagtgt atgtaagtgt atttatgtaa tatattagtc tacttaagta
     7321 atatgacaaa tgattataag tggattatga tactataatg tgaatctaaa taaattaaat
     7381 ataaattgat agtggatatt ctatttaatt aaatttaaaa agctaccttt acttataagt
     7441 ataattaagg tagcttttta aatagaggta gtgtgattaa agagaatttt taaatataaa
     7501 ttgtgaagct ttaatataga tgacaatata tattttgcaa atatgacaca gtgttttcgt
     7561 atttaagatg ataaaataaa taggaattaa tgaagatatt taaaaaataa aaataaagaa
     7621 ttaatagaag atattaaaga gatagagata aaagtgttaa tagaagatat tgaaaaagta
     7681 aaaataaagg attaatagaa gatactgaag aggtagaaac aaaagtgtta atagaagata
     7741 ttgaaaaaat aaaaacaaaa gattaataaa aggtactgaa gagatagaga taaaagtgtt
     7801 aatagaagat attgaaaaat aaaaataaaa gattgatata atatactgaa gaggtagaaa
     7861 caaaagtgtt aatagaagat actaaaaaag taaaaataaa ggactaataa aaggtactga
     7921 agagatagag aaaaaaatgt taatagaaga tactgaaaaa atagaaataa aaaattagga
     7981 ggaaaattta tgaaatatca ggtttcatta ttagcagtga aggatattga agtatcaaaa
     8041 aaattttaca aagaattatt tgagcaagaa attgaattgg acttaggcaa aaatgtaaca
     8101 tttaaaggag gatttgctat acaagaagac ttcgcatggc ttacagggat taatccagat
     8161 acaattatac aaaaatcaaa taatatggaa ctttattttg aggttgatga ttttgacgaa
     8221 tttattgaaa aactcaatta ttataaagat gtagagtttg tccataagcc actaaaacat
     8281 gaatggcaac aaagagtagt gcgtatttat gacccagata agcatattat tgagatagga
     8341 gagtctatgg aagttatagc tagaagatat ttatctgagg gatactctgt agaagaaact
     8401 tctaaaataa ttcaacatcc aattgaattt gtaaagcagt gtgaaaatag taaggaatga
     8461 ttgtttaaat tataattatt tagtagaaat taattgtagt ggaactaatt caagataata
     8521 tataggacta gtatttgaca aatgtcataa attaaattaa aataaagaaa atattaataa
     8581 agaaaaataa ggggaatatt aataaagaaa aaataaatat aatattaaaa tatattaata
     8641 aatttgaata tttataatat ttttaatttg aagtaggaat acttaaacgt ataaagttta
     8701 ttatcggaaa tttctatatt aatatgtagt aattcaatat tattataaag gagtggttat
     8761 tattaaggca attgaacttt ataaaaaatt agatttagaa tttaatatta aaaatattaa
     8821 tgatgattgg agttttatga attttgaaaa tgattttatc actccagaat ttagaaaaaa
     8881 gtacatatga ttagtattag ataatgctca aaatattaat aaagtataca caactacttt
     8941 tcctgataaa gaaataatta agcaagttat agataaagat gaaaaagata ttttaatttt
     9001 ttcacatcac gcaatgggat acatagcatc agatgaaggt tttccatttc acgacatacc
     9061 actatcttat atggaagaga tgaaaaatcg tagaatttct ttttatgtat tacattctcc
     9121 actagacaac tatagtgact attcaacttc tgttagtttt gcaaaagcta tgggtttaga
     9181 aatagtcaaa ccattttgta aatatgacga taaaattgag gtaggagtta tatgtaaaac
     9241 atcactaaaa tcaatagaag agattaagga attaattaaa aaatctgttg gtcatgatgt
     9301 gaaattgtat gattatggag attctgtatt aaaagatggt ttagttgcta ttgcagcagg
     9361 gggaggaagt tatccatttg tagcaagaga agttgctgaa cttggtataa atctatatat
     9421 tactgggttt actaagcctt taaaacattt tgaaccagta ttagagttcc atcaaatagc
     9481 aaaagataat ttaattaatg ttataggtgc tactcattat tctacagaaa aatttgcgtg
     9541 tatgggcatg gttgattatt ttaaaaatct aggtttagaa tcagagtttt tgcaaggaaa
     9601 atattactta gaggatttat aggacatatt aaacaataaa aataaacagt tagtaaaaat
     9661 ttattttact aactgtttat ttttttacct atttatccag tgttttgaaa aaatctatct
     9721 ttatttttta aactaagaaa atagactttt aattgttgat tagaagattt agttttgatg
     9781 tcttttaaat tatttttcga tattttttag tttatttttt gatgtatttt agattattat
     9841 ttaggattga ttagaattta taaatattta ttttagatta ttgtaaatat ttatttaaaa
     9901 aaaatagaat tattatattt atgataataa atggtataat aaaaggtaaa gtgtcaaata
     9961 tgcactaaat taaataagtt aattagtata taggttaaag tggaagtaat taaaacttat
    10021 taagtattag aaaatgactt cttattagag taagtatcta aaatgatata aaaattatga
    10081 ttactcatta aagtgactat tatagagtag ataaaattgc ccataaaaat agctataata
    10141 gagtggataa gattactcat taaagcaatt actatagagt agataaaatt actcactaaa
    10201 ataactataa tagagtggat aagattattc attaaagcga ttactgtgga gtagataaaa
    10261 ttactcacta aaataactat aatagagtag ataagatact cattaaggtg attattgtag
    10321 agtagataaa attacccatc aaagttaatt atcacatatt agataagatt attcattaaa
    10381 gttactatca cagagtggat aaaattacac attaaaattg tctgttaaag aatgaataaa
    10441 aaagagattg ctcaatataa gaagcatata aaaaatcaaa catataaaat ttaataaata
    10501 ataactgata gggaaaggaa agatagaatg atatttacaa aaagcaataa atacgataag
    10561 gactttctca tgaaaaatat gatgggacct aattgtataa aaatattgga agaattaaca
    10621 agtaagataa aactagaaaa gggaatgcgt attttagact taggttgtgg taagggtata
    10681 tcttcgatat ttttagcaaa ggaatttgat gctactgtat ttgcaacaga tttatggata
    10741 gaaccaactg aaaactataa aagatttaaa gagtttaaat tggatgataa aatatttcca
    10801 atacaggcag aggcacatga actaccttat gcagaaggtt tctttgatgc ggtgataagt
    10861 atcgattctt atcactattt tggaaacaaa gaaggatttt tagacaatca tatatcacct
    10921 cttgtaaaag aggggggaat acttgctatg gcaatgcctg gattaaaaga agattttgtg
    10981 gattgtatac cagatgaact cattccattt tggcaagata atatgaactt ccattcaatt
    11041 acatggtgga ataaactttg gtctgaatcg gagtctgtga ttgtagagaa atgtgaagct
    11101 ttaaattgtc atgatgaagc ttggaaggat tggataaatt gtgataattc atatgctata
    11161 aatgacaaaa aaatgatgga agtagagaat ggaaagtatt ttaatacaat ttctttgata
    11221 gcgagaacta aataattgtg atgaatttat aaaagtataa gataagtaga aatataagtt
    11281 gaatgagagt ataagaagca tagaaatata agttgaatta aagtagaagg taaataaaaa
    11341 tgtaagttaa ataaagagtt tatacaaaaa tgatttttta gattatttat acccaatcga
    11401 gttgcttagg tcagttgggt atttttattt ttttaaagtt aaattgcaaa tactattgtg
    11461 tgatatatat tttaatacta aatgtttgtt ttataagaaa taaactaata gaaaaaatag
    11521 ttttaacaat gaaagcaaaa aaggtattga tgaagattaa aaattttata gtaccatttt
    11581 atatattttt ttatatattt tattatactt taaatcaaat t
//
LOCUS       DAEQJM010000096        11251 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.097, whole genome shotgun sequence.
ACCESSION   DAEQJM010000096 DAEQJM010000000
VERSION     DAEQJM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11251
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.097"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(26..451)
                     /locus_tag="KRQ43_003323"
                     /pseudo
     CDS             complement(26..451)
                     /locus_tag="KRQ43_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
     gene            complement(924..1211)
                     /locus_tag="KRQ43_003324"
     CDS             complement(924..1211)
                     /locus_tag="KRQ43_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743662.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(1231..1506)
                     /locus_tag="KRQ43_003325"
     CDS             complement(1231..1506)
                     /locus_tag="KRQ43_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743663.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAIGMLKGVDYEPLIVATQVV
                     AGTNFKFICNATSVTNPPHDYLAEIIVFKPLPCDEHNATITSINIIK"
     gene            1694..2513
                     /locus_tag="KRQ43_003326"
                     /pseudo
     CDS             1694..2513
                     /locus_tag="KRQ43_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(2772..5339)
                     /locus_tag="KRQ43_003327"
     CDS             complement(2772..5339)
                     /locus_tag="KRQ43_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH2743664.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTNQLEDVSKKIGELFHNGEMPQEVSDAIKTAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMDGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIALQSEKE
                     LWGLSEWVKQNNSINLYLQNSPAIKIAEDFMSSVMPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAYSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     APQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(5342..5947)
                     /locus_tag="KRQ43_003328"
     CDS             complement(5342..5947)
                     /locus_tag="KRQ43_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2743665.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPSDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(6321..7781)
                     /locus_tag="KRQ43_003329"
     CDS             complement(6321..7781)
                     /locus_tag="KRQ43_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH2743666.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDRAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            8120..8698
                     /locus_tag="KRQ43_003330"
     CDS             8120..8698
                     /locus_tag="KRQ43_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2743667.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIKRHNLKLKIEKEKAFGVCNS
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            8990..10240
                     /locus_tag="KRQ43_003331"
     CDS             8990..10240
                     /locus_tag="KRQ43_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2743668.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            10401..10970
                     /locus_tag="KRQ43_003332"
     CDS             10401..10970
                     /locus_tag="KRQ43_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH2743669.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVDFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAVAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         3718 a         1953 c         1578 g         4002 t
ORIGIN      
        1 tcacgagtgt gcgtagctat tttttaatca atacaattac tgcacatata gatgcagaat
       61 ttttaaatac ttcacctaat gaaactgctg cactaatatc atgggctact cccctattgt
      121 cgctaaaacc tgcagtatca cataattttg catccattcc ttctattggt tttctcatat
      181 ttacaatgtt tgggtataaa gtttgagaaa cagctcctga accaatctct gccacagggt
      241 ctaagcaatc aatatatgat ataccagtat cttcatcttc tacttccatc attacacatc
      301 ctgcaagata gttaattgca gtacttttgc cacatcctgt cccaccaaga attagaatta
      361 aattttgatt ttcagcctta tttattgcta cttttccttc atttaataag agtgttattt
      421 cttctaaaag ttgattgtta ttttctggca tttattttcc cccttggtta tatattttat
      481 ttaaataaag tttaatccct taagtagatt acaaagtttt tagactatat ttaaatttgt
      541 tttttatttt taataaattt gcattttcac tcaataatta ttcttctttg tttattaaaa
      601 taactgtgtt gtataatata atttttacca acacagttat tttatttaat gcgcttattt
      661 tattgtattt tatgtaatac agttgttttt ttatattata tgtccactat tttcctatgg
      721 ttattacata tagattttta attatatttg taccattaat ttaaacattc ctatactact
      781 gcttaagttt tacacctata ccagcttgaa tattttattt ttatttgctt aaatagttca
      841 actatactgg tttaataggt ttcctttagt ttaaatagtt cacctatacc tacttgaata
      901 gttcactttt atttgcttaa attctatacc aatactggct taaacattat actaccatga
      961 ttgtattgtc tatcttcaac tacaataaaa acaggttcta aatctttagt agatgttatt
     1021 tttaattcta aaaaaacatt atcagttggt aatattttta catcataatt atttaaatta
     1081 ttattcgtga tactattaaa tacatcacct tgacgttcaa aaaaaacatt atcaactatt
     1141 acaaaataaa catcttcttt tctactattt tcaacctcta tagtattttg tttagttaca
     1201 tttagtctca tcttccacct cctattaata ttacttaatt atattaatac ttgtaattgt
     1261 tgcattatgt tcatcacaag gaagaggttt aaaaacaatt atctctgcta aataatcatg
     1321 tggaggattt gtaactgaag tagcattgca aataaattta aaatttgttc ctgctacaac
     1381 ttgagtagca acaataagtg gttcataatc aacccctttt agcattccta tagcttcatt
     1441 aaatactttt aaatcttctt cttcgacagc cctaaatttt gaccatccac caacaaaaag
     1501 actcatataa aaacctcctt tatatatata tttatttata tgatagtacc aattttctta
     1561 atattcaata tattacgtct aactggtcaa taaaaatgca taactggata aaaagactta
     1621 taaaatagct taactttaca tataataaga ttattctaaa atatgagaca tatcttgctt
     1681 tgaatatatt ctatacaaca attttccagg cctcattgcc aagtttaagg taactgactt
     1741 tggattccaa cttcttgatg ctaataaaaa atattttgat atgttcaaag ataatgtaaa
     1801 ttttctatta gatgatataa atttagaagg ttatcttaac aatgtgtata aatatcataa
     1861 tgattttaaa tctgggagat gcgtttgttt ttctatttct ccacaaacta ttaatggaga
     1921 tatttttcac atgcaagttg tagctgaatg tatagattgg gaagatgata agcctatata
     1981 tcttttaata tattcagatg taacgacatt ggtaaaacaa tatgtctcat tatcattttt
     2041 catccaagaa ttttatcaag aaatatgata aaatagctaa aaaatatgat attccttctc
     2101 accttataga aattgagatt acagaaacaa ttgtatttga agatgtcaaa gtatttagtg
     2161 aaataataaa tgaaattcat aaaaatgact ttaaatgctc tattgatgat tttggaagtg
     2221 gctattcttc aatcaatatg cttaagggta tttatgttga tacattaaaa ttagatagag
     2281 cattttttca atcagaagat ttagattctc aacgtgaaag aaatataatt gtatctataa
     2341 tcgaactagc taaaaagtta aaaatgacca ctgtagctga gagaatagag accagttttc
     2401 aaaaagattt cttgcaagaa ataaactgtg atatgttaca aggatacgtg ttctctagac
     2461 ctttgcaaat aaaagacttt gaaaaactta tgtttcaaaa ctcctccaat taacaatata
     2521 aaattgctta ttataagtgt attattgtat caacaaataa aggaattgtc tcaaaattga
     2581 ttttttctaa tcaaattttt attttgagac attctcattt ttttgcataa gaaaataccc
     2641 accaagctac ggtttttctt accgctgttc ggtgggtatt agtagtatta tgaaatctga
     2701 aaactttaag tattactact tccgctaacg caatcacaaa ggtcgaaagc ttcaaagcga
     2761 aaataggctt tttactcatc aaacgtcacc gtacctgcca acccgtccac cgttatcatt
     2821 tgtccgctct taatagttcg tgtggcaatg tgtgtagcca taacggctgg gatgccatat
     2881 tcacgtgcga caatgcttga atggctaaga ggaccaccaa tgtccgttac aatcgcactt
     2941 gcagatgaaa ataatggtgt ccatgctgga gttgtggtaa ctgcaaccaa aacacttcca
     3001 ggttgaaagc tttcaaaatc tgctggacta ttcagtacac aagctggagc cgtcacaaca
     3061 ccagtactgg taccaatgcc cgtcaacaca attttcccat ctttctgctt ctgtggtgct
     3121 tgtgatatag tttttttgtt tttctctggc aacttggacg gtgacacata acccatgtat
     3181 tttttaagtt cagcttttcg aacaggtatt atcccgttca tatcagatag agacttgttt
     3241 ttatccaact gctctataag tacctccaat tccgattttg tgagccaata aatatcatct
     3301 aaatgtgaaa tagctcctcc tcgtatgaat cgttctgaga tttcctgaaa catacaacga
     3361 atcagaggat gtcccattcc catcaaataa atagcatttt cacgcatagg agaggtttcc
     3421 tgtgcccaat ggagcaactt aaaaaatagt tttttacgca atccacctat gtgttgtaaa
     3481 atctcttctt ctgcatgttt tctacgcttt tcaaacgtgg tctggcgtaa aaaaggactt
     3541 tccccttttc cttccacaaa tgtttttacg gattcaaaag ttggtgtaag tgtttcctgc
     3601 ggtgtggaat acgcaaaatc aaactcataa gcggtacgac caaactcttt aaagtactta
     3661 ttgattcgat ttttccattc tatccatact tcctgtgaaa ctccaacagg cataactgaa
     3721 gacatgaaat cttctgctat ctttattgca ggactgtttt gcagataaag gttgatgctg
     3781 ttattttgct ttacccattc tgaaagaccc cacaactcct tttccgattg cagagcaatc
     3841 gtatcaaacc caagcaggaa aacggaagta tccgttatac cagcacgtcg aactgctcct
     3901 tgaaataatt ttgtaaataa tgtttcactg atagaagcag caggcaatgt aagctgaatc
     3961 cttgtgaaat aaatacatgc ggcataaaat attgtctgaa taccatccat aatttgatgg
     4021 gcgttcatcg tatgcagggg cttttcttcc cattgtttaa tagcatcctc atatcctttt
     4081 cgtgccgttt cccagcgtgc aacgctgttc ataagtgtcc tacgtaaaga gcgtggggaa
     4141 agggatttga tagcaatcaa aagtggcttt gatttagcag aaagataaac atatccatta
     4201 ataaccgtat atgcgccgtt ttttggtaat aattttttcg cacttttacc aaacatatct
     4261 atccataaaa gctccgatgc acggtttacg atttcaagac caagcgtggc gaacaaaggt
     4321 gtaacaggat ttggcaagtg ttctgccaaa cttccctttg tgtatacaac atcctgttct
     4381 ggcaataccc attccggtgg cagaacagta attggacgag cttgaacaat gtacaattta
     4441 tctttttcca gtgcccactc tacatccata ggcatttgat aatacttctc aattttcttt
     4501 ccaagctgta tcagttgcat tacctgatta cgagtaagag catatttttt tctcaacctt
     4561 tcaggaacca tggtttcttc tgttccttct gaagtacgaa ccgtcataat ctctttattt
     4621 gccacttcat acgatataat tcgttcggag tccttatcca ctacgattgt atcgggtgta
     4681 actaagctag aaaccaccgc ttcaccaagc ccccatgcag cgttaataat catttcgcta
     4741 cgtctaccat tgattgggtt taacgtaaac ataataccag atgaatcgga aaatgcaagc
     4801 ttttgtacta caacagcaag tgcgacaatc tcgtgcttta tattattctt cacacgataa
     4861 gcaatagcac gagctgtcca taaggaagcc cagcatctct ttacagcgtc aataacttta
     4921 tcttcacctt gtatgttaag ataagtttcc tgctgacctg caaaagaagc gtcaggtaaa
     4981 tcttcagcag tcgcagacga acgaacagcc accgatatgt tccctaatcc ggcataagct
     5041 gttttaattg cgtccgacac ttcctgtggc atttctccat tatggaaaag ctcccctatt
     5101 ttcttagata catcttcaag ttggttggta ttattggaat caataccatc tagcagttta
     5161 ttaattcgag actgaatatg gttcgtctca acaaaaatct ggtatgaagc agtcgtaaca
     5221 tgaaaaccgt ctggcacagg gatgcctgct gtcaatagtt ttgataaaga catccctttt
     5281 ccaccaacaa tttcaatggt tgcttgttta tgttccagtg gcaagacata ataaatcata
     5341 atcattcacc tccatcattc ataattccgt gcagaaatat attcattgtt tcatccaaca
     5401 ttttttccga actatccgat ggtcgtgacg tgtagctgat tgataacatg gagttaatta
     5461 acaaacgtgt cacaagagcg gtatccgttt tgcgaaagat gcctgtggtc acaccattat
     5521 caattaccga ttttataata tcttgatatg cataacgagc atctttaagt ctctttcgat
     5581 actcttcttc taaataatca gattctgtat ttaaccacat cagtacagtt ctatactgct
     5641 ctggaaatct aagatgatta agcatgattt ttctaaggca ctgttgtggt gaaggttcac
     5701 catcaataat cctatgaact tgttggatag ttttttctat ttctttctca actgcatata
     5761 caacaatctc gtctttcgtt ttgaaaaaat cgtatagact tgactttccc atgttggcta
     5821 aaactgcaat ttctctcatt gatgtttttt ggaatccatt ttcagccatg agactcaaag
     5881 caacagcaac tattttttct cggcgttctg cttgttgttc aggtgtaagc acaattcctt
     5941 ttggcatagg gcgatacctc cttttagcga ccaatggtcg tttctttttt atttatcata
     6001 cagcgaccat cggtcacttg tcaaggttaa tttttttcat tgtatatggt actcgagata
     6061 aaaatgttca ttttagaaat tgctctattt aagtagaaat aggcttcatc attagaaaac
     6121 aagactataa atttgagata tttatcatgt tcaaatttca tcaatatcaa agtttaagat
     6181 attaataaaa aaagaattac taagaaataa catataaaga ttcaaaaaag gagttgaact
     6241 taaaattcaa ttacaaaaaa tcaaatttaa gacaactcct ttattcttta tctctactat
     6301 tctttatctc tatttattta ttacaactcc ctaacattta ccactactgc cttaggtcta
     6361 gtcatagcct cgattgaata cttaacacct tgagttccca taccagatgc ctttacacct
     6421 aaaaatggga agtggtctgg acctctttca gtcttattat ttatttgaac agtaccaact
     6481 tcaagtttat cagctatata aaatgcccta tcaatatcac ttgtaaatac tgatgattga
     6541 agcccatact ctgattgatt agcaatttca attgcttgat ttatatcttt aactcttata
     6601 attggaagta ctggaccaaa tggttcttcc caagcaattt tcatatcaac atttacatta
     6661 tctaacaatg ttggatagaa taaattattt tttctaacat tacctgttat taactttgct
     6721 cctttatgta atgcatcatc aaccaaccct tgaacaaaat cagttgcttt attatctata
     6781 agaggagtga taactacttc atccattgga tttccaattg tcaacttctc taccaatggc
     6841 tttatttttc cgactaattt atccgccaca ctctcttgta ctaaaattct ctttactgcc
     6901 gtacatcttt gtcctgaata tgaatacgct ccagatacta tattcttagc tgcaaaatct
     6961 aagtctgcat cttctaatac tatagccgca tcttttccac caagctccaa taatagtggt
     7021 accattccag atattttaga tatatgctga ccaacttcag tactaccagt aaagttaata
     7081 aaattaattc ctttatgcgt tacaacataa tcccctatct cactacccct acctgtaata
     7141 gtattaagta ctccatctgg tatcccagct tttctcatga tttctaccac atgaagtgcg
     7201 ctaatagccc cttgtgtagc aggttttaat acaactgcat ttccaccaat aagcgctgga
     7261 gcaatctttg acattgataa atttacagga taattaaaag gagatatagc taaaacagta
     7321 cctaatggaa cccttgaaac ataagacatc ttatttcttg ttccaccagg gaaattatct
     7381 ccactaatgg cttcaccctc catatttttt cccacatcag ctgtgtatct taaaaaatct
     7441 gctgttctct caacttctgc ccttgcagat tttatgtctt tggctatttc aagtaccagt
     7501 atattagcta tctcatctat attttctaac aataaatcag cagccttatg aaatatattg
     7561 gctctcttgt atacaggcat ttcagcccat acttttatac tctcttttgt gttttttata
     7621 acctcatcta cctcatgttt tgtcatagat tgtactttcc caacaagaga attatctatt
     7681 ggtgagtaaa tttctattgg ctttctcgaa ttagattcta cccattttcc atttattaaa
     7741 tttttatata cattttcttt tgttttaagt tcattaaaca tatttttatt cctctctctg
     7801 atataacttt gtgtatttaa attatagcca tttattcgtt atgtaaacat ttcttttttt
     7861 cataaacgtt tacctataaa aaaaatttta agttaacgtt tttctagatt cttctatttt
     7921 aataacatac tcgctccaaa tctatatagg tcacacttta atatcaatat accaatatac
     7981 caatatacca atataccaat ataaatatta taaacataaa tcacttgaca aatttataag
     8041 tagacaatat tatatatcta tgacttaaaa tatttttaaa gtcatagata gcatatgcag
     8101 atagaaagga ttgataaaaa tggctaaaag ttttacagaa atagaaaaag acaatataag
     8161 aaaaagacta atttcagaat gtgaaatcaa ctggtctaaa tatggataca aaaaaactaa
     8221 cattgatgaa ctttgttcaa aatcaggaat cgcaaagggt tctttctata cattttttga
     8281 ttcaaaagaa aagttatttt ttgaagtact aaatggaatc caaaacagac ttatatcatc
     8341 agtagatgaa attttaagta acatgcctcc aaaagaaggc tttgcaaaat ccttaaaaat
     8401 gttatatcga ttatatgata aaaatccatt tttatattca ccaaataatc ctgatttcat
     8461 cagcctaata aataaactac ctcaagatat gtttttacaa cttgagtcca ataacataca
     8521 aagtttttac gacttaatta agagacacaa tctcaagttg aagatagaaa aagaaaaagc
     8581 ctttggtgtt tgtaattctc tactatcaag tctattggta aaagaaaata ttgaatataa
     8641 ctatattgaa gtatttgatt ttatggtaga taatcttgta gaacacatac ttgaataaca
     8701 atttaaaata atttttctaa atatttcttt atactaaaga ggattaatat gattgaatta
     8761 atgaaaaaaa taaacaatat catttacaaa ataaatgata aactaaatat acacacaaaa
     8821 cttatagacc ccagagttaa ctcattccac tctactctaa gccatctata atagttcgta
     8881 tatttctaat aatattagat attaaagtaa gaaaaaaatt ccttataata attgctatta
     8941 tatcaattat tataaatatt ttaataatct tagataggta ggtatatata tggtaaaatc
     9001 ctcaaacact tttaataaaa acttcaactt gatgatatta ggtcaaataa tctcattgtt
     9061 tggtgcatca atacttaaat ttgctttatc tttatacata cttgatataa ctggtaaagc
     9121 agaaatattt gctactatac tagcagtatc ttcaatccca attatagtat tctcccctat
     9181 tggtggagct attgcggata tattcaacag aagaaactta atggttattt ttgatttttc
     9241 aagcagtctt acagtactaa tcttagcagt attcttattc aacaataatg gttcaatatt
     9301 acttgtagga attattatga ccatattatc agttataagc acaatgtatc aaccaactgt
     9361 tcagtcaagt acaccccttt tagttgataa tgagcattta atgaatgcaa atggtattgt
     9421 agctggagtt gcatctctta caaatattgc aggacctgta ttaggaggtg tcttgtatgg
     9481 tgtgattgga attaatgcaa ttatagttat aagttgtgta agtttctttc tatctgcaat
     9541 tatggagata tttatacaga ttccttttat caaacaagag caaaacagca acattataaa
     9601 aactatattt actgatataa aggatggtat tgttcatata tgtaaagaaa atagatttat
     9661 actaaaaata ctttttttag ctatagcaat aaacttattt ttaagctcta tgttaatagt
     9721 tggtatcccc tatatagtaa aaatcactat gggagctagt aacttcttat atggtctagc
     9781 agaaggagca atttctttta gttcactggt agctgctgtt agtattggta ttttctcaaa
     9841 acatctaaaa atcactaatt tgcacatttc ctttattata tgtgcagtta tgttcatacc
     9901 aatggcggtt tcagtatatc catttatatt aaacacagga tttccagttc catttttaat
     9961 ctttatagta tcatctatgc taatattttt tacaacgact cttatctcaa tatatgttat
    10021 aacagtcaca caattaaaaa ctccaaatga actcttagga aaagtaatgt caattctttt
    10081 tgcaggaaca gcaattgcaa tgcctcttgg tcaggttatg tatggtaaac tttttgattt
    10141 attatcagat agagtgtaca tcattatact aggagttgga tttattacac tacttatagc
    10201 atttgtatca aagataacat tgaggaacga aaatctttag atacaaagaa tttagatata
    10261 aagatttaat tttcactaat ttctgaattt aaatgcaaaa ttgcgtatca gtatgttgac
    10321 gttttagaaa ttgattgata taatcaatgg aaaataaact ttataaaaat tcaaaatatt
    10381 cagctagagg agtgataaaa atgagttaca tgccaacttt agaacaagca tgggaaatat
    10441 taagaaaata caataaggaa gaatttcata taagacatgc tcaaattgta tctggagtta
    10501 tgagatacta tgcaaaggag tacgaccctg agagagtaga cttttgggaa atagttggac
    10561 ttttacatga tttagatttt gaaatgtatc ctgatgaaca ttgtgttaaa caaagagaat
    10621 taatgacaga gcttgattta gataaatcaa taatcgattc tacaataagt catggatatg
    10681 gattaactgg ttcagatgtt aaaccagagc aatttatgga gaaagtatta tttgctgtgg
    10741 atgaacttac tggtttaatt ggtgctgttg caataatgcg tccttcaaag agcgtttctg
    10801 atttagaatt aaaatctgtt aagaagaaat ttaaagataa atcatttgct gctggctgtt
    10861 ctcgagacgt tataagaagt ggtgcagaaa tgcttggatg ggaacttgat aagcttatcc
    10921 aaacaactat agaagctatg agaagcttga ttccagagat ggcaatatag ctcctcatac
    10981 atataccata gaagttacat ctttaaagag catttctctt tttgatgcaa cttcttttta
    11041 tattttgtag aataaaaagt ttaatatttt aaactcacta tataatctat aataaatact
    11101 ataaataata taatgtataa tagtcataaa ctttctaacc ttaaaagttt ctaatactca
    11161 ataaacaatt ctaatataca agtggcatta tatgatttaa ttatatatct tcaatttata
    11221 tattaaaata aatatatata ttaaattctt a
//
LOCUS       DAEQJM010000097        10820 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.099, whole genome shotgun sequence.
ACCESSION   DAEQJM010000097 DAEQJM010000000
VERSION     DAEQJM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10820
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.099"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            467..1327
                     /locus_tag="KRQ43_003333"
     CDS             467..1327
                     /locus_tag="KRQ43_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH2743670.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            1317..3188
                     /locus_tag="KRQ43_003334"
     CDS             1317..3188
                     /locus_tag="KRQ43_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH2743671.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRLTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEASNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            3208..4662
                     /locus_tag="KRQ43_003335"
     CDS             3208..4662
                     /locus_tag="KRQ43_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH2743672.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLMDLYLKYSETVI
                     RRFDDKVKYWITFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            5686..6894
                     /locus_tag="KRQ43_003336"
     CDS             5686..6894
                     /locus_tag="KRQ43_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743673.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNVLPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFRLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            6925..8304
                     /locus_tag="KRQ43_003337"
     CDS             6925..8304
                     /locus_tag="KRQ43_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2743674.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELSAY
                     GHGCGHNLLCTAHVGAVVGLKREMLENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            8410..9600
                     /locus_tag="KRQ43_003338"
     CDS             8410..9600
                     /locus_tag="KRQ43_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2743675.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEESTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEIIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(9728..10792)
                     /locus_tag="KRQ43_003339"
     CDS             complement(9728..10792)
                     /locus_tag="KRQ43_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743676.1"
                     /translation="MFLKLIFKYNTLDFSRAYFDLTDWADNPKDISYYLSNGTFGDLM
                     DSIDENASKMSLSDIAKLEKKIAKKHINLWNEGKIDFSTTRFSSIVPMLQNAGVNFHF
                     IYPDIDLLKNTFNNLIKDIHLHRMKGNQPSVIYITVKDTNYDDSTLDQVYKILNSIKK
                     DKLTDFIIEKNSNSFKIFTKCETIKSLTKNFTACYIKESIENSTNIKVCVGYGIGNDI
                     KQAMSSAISANKESKINPLNYSFLVNENYETIGPLLCDKLLTVSNKVTPHINTIAKSS
                     KLSTLTIQKIISVTEILQRDEVTPKELSSCLNVTVRTANRFLSSLLKSGNATILYEKQ
                     NSTKGRPERVYKLFISENKY"
BASE COUNT         4037 a         1207 c         1959 g         3617 t
ORIGIN      
        1 tagcatttaa ataaaactaa atttgaagct ttacctatta atatatctta atagtgatta
       61 aataaaacta aacttaagaa tttatttatt aacatacagt tcattatatt taaaatcatt
      121 actatgataa ttcataatag taaaatagat aatggttcag acaatattgt aaatattagt
      181 gacagtaaaa tagtatcaat ttagtatata aactttgcca gataatcgca taacagagct
      241 tgtagttata gaataaaaaa atatctagga aaccgttgac agatttatat ggatagtata
      301 acatatagaa tatgaaatta aacaaaaaag aattttaatt atggcgacgt agtcataatt
      361 ttgagtatgt tactgattag caggcagaac tcaagtatat atgtgaaaaa tagagggata
      421 ctctatacat atatgcttga gttcttttta ttgaaaggag gaatatatga aaataattca
      481 gattttaaat aataatgtag ccttagtaaa aagaggtaaa aatgaaatta ttgtatttgt
      541 taaaggaatt ggctttaaaa aaagagtggg acaagtaata aatgaaaatg aaatagagag
      601 aacatatata ctagattcat acgatatgct agaacacttt agttatctac tacaaaactc
      661 agactccaat aatatagttc ttattaatga aataattgaa tatggtgaga aagctttaaa
      721 tataaagtca agtgattatc taagcttaac cttactagac catttagagt ttttacttaa
      781 aagatgtgaa aagaatcaat ttataaaaag tcctttggta tggaatgtta aaagatttta
      841 tccaaagcat tttgaaattg gaatgcatgc actaaaatta attggtgata gtaagggaat
      901 taatcttcct gatgatgagg cagtatcaat agcacttcat tttgtaaata tggaggtaaa
      961 taaagagtct catgatagta caattgtaga gttgagaact ttagcagata tagtttctat
     1021 aataaaatat cattttaatg tagagctaga tgaaacttca acaaattata tgagatttac
     1081 tactcatcta cagtacttta tccaaagaat tatgtcagat gaagcttcaa tagatgaaga
     1141 taattctata gatttatata aacaagtaag tcaactttat ccaaagtcat ttggaagtgt
     1201 tcaaaagata agaaaatata taaaatcaca atttaatgtc gatatatcta taagtgaaga
     1261 aacttattta atgttgcata taaatagggt gactcaaaga ctggaggcaa aatcagatga
     1321 aatataaaga tttaaatgaa aatataataa aacttatagg gggaaaagaa aatataaagt
     1381 cggtagcgca ttgtgttact cgtttaagac ttactttaaa tgatagaagt atcgctcaaa
     1441 cagaagaaat taaaaaatta aaaggagtaa ttgatgtagt ttctaatgat gttgcttatc
     1501 aaattataat aggtactcat gttgtagatg tatataacga gtttatgtct atgataggtt
     1561 taagttcaag tgaatcaagt ataaaaagtg aaagaaaaaa gggaattaga ggtatcaaag
     1621 gtatatttaa ttccatcttt gtggtagtct cagagactat gacttcagta attgaagtac
     1681 tacttgcagc tggtatactc gcaagtatat tagcactttt aaatatgtct ggcatacttc
     1741 agagtgatag ccctacatat caaatattag atacattaag aagtgctaca tttcacttct
     1801 taccagtatt aattgcaata gcatcagcaa aaagacttaa tgtaaatccc tatatagcag
     1861 tagtgttagc agttacgtta ttatcgtcat caatagatgg tgtagaagga ttaagtttat
     1921 ttggtataaa tttacaggct acaacttatg caaacagttt tattccaata cttttaggag
     1981 tatgggcaat gggaattata attgaaggtt tgaaaaaaat attacctaaa gcactacact
     2041 attttttagt tccagtgtta tctttaataa taaccctatc agttacatta actgtatttg
     2101 gacctattgg tatgtggatt ggtgatggat taaactatgc atgtatgttt ttaattgata
     2161 cattgggtaa ttggagtgtt gttgcactgt atgcagcttt acaaccactc ttaatagttt
     2221 ttggtgcagc aaactttact atgcctatat ctttaaattc tgtgacaaca ttggggtatg
     2281 acccaatttt tatgggcgct gcaacaatat ctgatattgc agtttgtggt gcaatgtttg
     2341 gatatttctt aaaaactagg aataaagaac aaaaacaatt atttgggaca gtaagtttta
     2401 gtgcacttat gggagttaca gagccttcag tgtttggtgt gtttatgaaa tatagaagac
     2461 catttgtagc agtaatgata ggtggaggta taggtggttt aatagcaggt ttagctcaag
     2521 ttaaaacata tggaatggtt tggggattag ctgcattacc aacatatctt gttggaggag
     2581 aggcatctaa ctttacattt atgataataa gtgtagtagt atcatttgta gcagcaacag
     2641 cagcttccta tttactagga ataccttcag atgaaaaaga agaagttaag ggtgataatg
     2701 aaaaagaatt agaactaata atcaacgaga acaattcaag aactattagt attggaaatg
     2761 ttgcaaaagg tcaggtaatt gcacttgggg aagttaatga caaagcattt tcctctggag
     2821 cattaggtaa aggggttgga gttataccta gtgaatcaaa atcaactgtt atatctcctg
     2881 tagatggaac tataactata gtatttccaa ctaaacatgc atatggtata gtgactgatg
     2941 aaggattaga aatattaatt catattggta tagatactgt aaacttagat ggaaaattct
     3001 ttgaaagtct tgtaacacaa aatcaaaggg ttaaaaaagg agatgcttta gcagtatttg
     3061 aatctgataa aattatagag gaaggctttg attctactat aataactgta gttacaaata
     3121 ctagcgatta tttagatgta atctcatcaa atgatgaatc agaagaatta ttaactgtaa
     3181 tagtataaat tttaggaggg aaaattcatg aatattaaag atacattttt ctggggagga
     3241 agtattgcag cccatcaatg tgaaggttca tgggatagtg ataacaaagg acctgcaatt
     3301 atggattttg taactaaggg ctcttatgaa acgccaagag taattactga taaaatagaa
     3361 gaaaaattgg attatccatc tcataatgga atagattttt ataatagata taaagaagat
     3421 atagctttat ttaaagaaat gggatttagt gcattaagaa tatctataga ttggtcaaga
     3481 atttttccaa atggagatga tgaaaatcct aatgaattag ggattaaata ctatgaaggt
     3541 ctgatagata cattaataga aaataatata gaacctattg taacactata tcattttgaa
     3601 ttacctatga atttagtaca taaatatggt tcatggaata acagaaaact tatggatttg
     3661 tatttaaagt acagtgagac tgtaataaga aggtttgatg ataaagtaaa gtactggatt
     3721 acatttaatg agatgaacca tattgaccct caaacagagc actcggatat ttttacttat
     3781 atgatagcag gtattaagta tagtgaaata gaaaataagg ttcaaacatt ggcaaatgta
     3841 gggtataata tgactttggc gggtgtaaag gttgcaaagt tggctagaga aatcaatccc
     3901 aacaataaag ttggatgtgt atttggacta aatccaattt atccatacaa ttgtaatcct
     3961 agtaatgtgt taaatgcatt tttagataat gatcgtgatt attatcaaat tgatgcaatg
     4021 tgcaatggga agtttcccca atataaatta aaagaatatg aaaaaaataa tataactatt
     4081 gaagtgactg atgaagacaa aaaagcattt aaagaaggta agttagattt tataggtctt
     4141 aattattatt tttcaagtgt atctactcca aaagaaaatt tatcaggtga taaatcttta
     4201 tttggtggga ttcaaaatcc atatttggaa caaagtaagt ggggatgggc aatagaccct
     4261 ataggtttaa gatttacctt gaactatatt tacagaaagt atcaattacc tatcttaatt
     4321 acagaaaatg gtttaggggc atatgataaa atcgaagaag atggaactat aaatgatgat
     4381 tatagaattg aatatttaag taagcatcta tctcaaatga agtctgcaat tgaagaggat
     4441 aatgttgaat gttttggata tttgatgtgg ggaccaattg atttagtcag tgcaactaca
     4501 ggtcagatga gtaagagata tggatttata tatgttgact tagatgatga aggcaaagga
     4561 agttttaaga gatataagaa aaaatcattt gattggtaca aagaagtaat aaaatctaat
     4621 ggagaagttt tagatttttc tacggatata gtagtagggt agtaataaga taaatagaag
     4681 ttaggaacta atgttaatta gtgtctagta aagcatttaa aatagagtat agggtcttta
     4741 aagtaaagtg tgtattctta ttaaaagtaa tggcaactaa aattactata aaaaggagaa
     4801 tacacatttt ttatgtttat acttaagtaa atatttagac atattcatag tataatttac
     4861 tcattatata aaaatagtat gatttactca ctatataact ttataaattt tctagaaaaa
     4921 tgtcagaata tattgacaaa aaaaagattt gaaattataa tctatattga gaatagtttg
     4981 acaatataaa aacaagtatt tttacaaata gtgaaattat ttttattgtc aatttaagaa
     5041 taatttagga ctactataaa gatgaaggta tagatgtcat tatatgataa atcatacttg
     5101 tatagaaaga attttaaagt atgcttatca ttgatttaat ataataaata atttttgttt
     5161 ctagtaatag ttcataggaa taagatatct aaattcgctt agaaatagtc taatttacaa
     5221 aggaggggat gcactagtag ataaaatttt tatataaaga agacttaaag tggagtatat
     5281 tctgataata ttggtttaat ggttatatta ttatttcgtt ttagatattt taagaataat
     5341 ttaagacgtt tgtaaaaatg tattctatat ctaatattta aataaatata agtcttccaa
     5401 catgtatact aagatagaaa gtagttgaag tacaattcta acttgtaaaa ttatgtagaa
     5461 agtaaaaatc aaaaagaaat ctagtaagtt gataattata gttaatattt agagagttaa
     5521 ctctagttat atttatttag atattttagg aataatttaa gacgtatata atatcatcaa
     5581 aaaatatcaa gctataccat atgtagttaa gaataactgc ataatataca ttttataatt
     5641 attgttttat tgataaaaaa ttattatatt taggaggaaa caacaatgga aaatttttgg
     5701 aatccactta cttgctttac tgtatgtgta atgatttatg cttttagtga gtttttatct
     5761 aagaaaacaa aaggtgcaat ttcaacattg ttatttgtat gtattatatt tttactagga
     5821 ttttggacaa atgttttacc aaaagacatt acaggagcat cagggatatt agctgcaatg
     5881 agcaactttg gtatagcttt attaataact aacttaggaa cacttataaa tcttgaagac
     5941 ttatgtcatg aatggaaaac ggttgtaatt gcattagtag gtattgtagg aataggggtt
     6001 ggctgtttaa cagtgggtag tatgttattt ggtagagagt atgctttaat agcagcacct
     6061 ccaatagcag gttctactgt tgccggtatt atcgtaacaa ctgttgcaga agctgcaaat
     6121 agacctgaac ttgctgcatt tgtaattcta gtattatcat ttcaaaagtt ctttggcatt
     6181 ccgataacta catattgtat aaataaagaa ttaaaattta aaagagataa cggggatttt
     6241 ttgaaagatg agtcaaaaag taattttaga cttccaagta tgagaatttt taaagaagat
     6301 ttaggtaaaa aatcatctac tctagtgtat cttgcaaagc tttcatttgt tgctatgatt
     6361 ggtaattttg taggattggc tactttaata ccaggattta cccctgcaaa ctattattta
     6421 aatcctaata tagcatgttt gttagtaggg ttgattttta cacgaatagg ttttttagaa
     6481 aaaggaattt tagataaatc tcaatctaat ggaattataa tgtttggttg tatgttgatg
     6541 ttacctggag gacttgctaa ggtaactcca acagcattgt ttgggatgat tgttccaact
     6601 ataggaatac ttgttgtagg ttctgtattt ataatattat ttactgcaat tgtaggaaaa
     6661 ctattgggat attctccaag aatgtcagct gcaattggtg taacttgtat gctagcttat
     6721 cctgcaacac agataatttc caacgaaggt attgatgcta tggaaggaac tgaagaagaa
     6781 aaacaaaggg caacagatta tttattacca aagatgatta taggaggatt tgttactgta
     6841 accattgcat cagtggcatt tgctagtata ataggtccaa ttatatttgg ttgatagtaa
     6901 atatacttat aggaggaata agaaatgata ggaagtatat ctataaatga gatagataaa
     6961 aaaagattca aacttgatga tttaagtaag aaaatatggg aaaacccaga aaaagcattt
     7021 aaagaattta aagcatgtga aaatacagca aactttctaa gaagtgaagg atttgatgtg
     7081 gaagtaggtg taggaggttt agccacggct attagagcta gttttggttc aggtaaacca
     7141 gttataggtt ttatgggaga atttgatgca ttacctggtt taaatcaaaa agtttcaaca
     7201 aagcaagaag catttgaatt gagtgcatat ggtcatggat gtgggcataa tttattatgt
     7261 acagcacatg taggggcagt agtaggactt aaaagagaga tgctagaaaa taacttaagt
     7321 gggactatag tattttatgc atgtccagga gaagaacaat taacaggtaa aggatttatg
     7381 gctagaggtg gagcatttga agggttagac ttagctataa attttcatcc aaataaaatt
     7441 agtgaagcta caattggtac ttcaacagct gttaactctg taaaatttca ctttaaggga
     7501 aagactgcac atgcaggctc agaccctcaa aatggaagaa gtgcactaga tgctgtggaa
     7561 cttactaatg tgggagctaa ttatttgaga gaacatgtta cttctgatgt aaggattcat
     7621 tatacaatta cagatggagg agtagcaccc aacatagttc ctgataaagc atcagtatgg
     7681 tattatacaa gagctttaag tagagaagct gtagaaagta catatgaaag acttgtaaag
     7741 gtagcaaaag gagctgcaat gatgactgaa actgaagttg aagtagagtt tttaggaggt
     7801 tgttataata ctttaaataa tcatgtttta gcaaatcttg tatcagaatg tatgaatgag
     7861 attaaacaag agccttggac tcgagaggaa ttggattttg cagctgaatt agatagacaa
     7921 agcccacaac aatataaggc tatgataagt aaatataatt tgccagaagg aactcatcta
     7981 tattatggtg gaggaaatgt tacaaacttt aatagttatg gttctactga tattggagat
     8041 gtaatgcata tagttccgac agcatacttt tttacagggt gtacgaatct aggtgcacca
     8101 ggtcatagct ggcagtttac atcttgtgca ggaagttcta taggagaaaa aggtatgata
     8161 tatgcatcaa aaatcatggc tatgtttgga gccaaaatat taaataatcc agagatagct
     8221 aaaaaggcaa aagaagagtt tgataaatct atgaatggta aaacatataa atgtcctatt
     8281 ccagatgata ttccaactcc ttaaaaagac atgaagttta atatataaaa ttataatttt
     8341 tatatcagca tcatttcatt actaaaagaa agtgagattt tgctgactat ctgattagga
     8401 ggaaggaata tgaaaaattt ttttaaagaa gcgcagtcaa tagaagggga aattattaga
     8461 tggagaagat atttacatga aaatcccgaa attggttgca atctaccgaa aacagtaacc
     8521 tttgttacca gtactttaga aaaaatggga tattctccga aattgacgtc taataatgga
     8581 atagtagctg ttttagacag tgaaaatggt ggaaagacct tattattaag ggcagatatg
     8641 gatgcacttc ctattatgga ggagacggat ttacctttta aaagtaagaa taaagatgca
     8701 tctcatagtt gtggacacga taatcacaca gcaatgctct taggagcagc taaaatactt
     8761 atggataata agcacttact taaaggtaga gtaaagtttg tatttgaacc agatgaagag
     8821 agtaccagag gtgcaaaatc aatgattgat gatggtatat tagaaaatcc tcaggtcgat
     8881 gcagctatgg catttcacag tatggtgggt aaatttctta acacaggtca agtagcttat
     8941 tcacgtggtc cagctatggc atctgcggat atatttgaaa taacagtaga aggaaaagca
     9001 actcatggag caagccctga atttggagtg gacccaataa acataatgtc gcatatacaa
     9061 atagcattaa acactatact ttcaagagaa aaacctcaga aagagcctgt agttttaact
     9121 attggtatgt ttaatgcagg aaacgtacca aatgctatac caaataaagc atctatgtca
     9181 ggaactttaa gaacatttga ccaatttgtt agagaaaaat taaaaaatag aattattgaa
     9241 atatctacag gaatagctaa atcatttgga ggaaatgcta aagtggaatt taaaatgggg
     9301 actcccgcag ttataaatga tttggatgta ggagatgaga ttgtatctta tgttaaagaa
     9361 attataggaa atgagaatgt aatagacttt ccatctgcaa tgggttcaga agatttttca
     9421 gagattttac taagggttcc aggagtattt ttatggattg gaatgggaag tattagtcag
     9481 ggatataatt ttggtatgca taatcctaaa gcaattttta atgaagaggg attagtttat
     9541 ggttcagctt tatttgctca ttgtgcagta aaatggttag aaaataattt tagtagataa
     9601 taacataaaa tattattaaa tatcataaaa ggtatatctt aaaaagatgc aaagatatac
     9661 cttttagaaa gtcatatata attttactta atattagatg ataaaatatt tttatgcatt
     9721 ttggatttta atatttattt tctgatataa ataatttgta taccctttca ggtctacctt
     9781 ttgttgagtt ttgtttttca tataatatag tagcgtttcc agactttaag agactactta
     9841 gaaatctatt agcagttcta actgttacat ttaaacatga agataattcc ttaggagtaa
     9901 cttcatctct ttgtagaatt tcagtaacag atataatctt ttgaatagta agagtagaca
     9961 atttagaact tttggcaatt gtatttatat gtggagttac tttatttgaa acagtaagta
    10021 acttatcaca cagtaaaggt cctattgtct cataattttc gttgactaag aaactgtaat
    10081 ttaaaggatt tattttagat tccttattag cacttatggc actagacata gcttgcttta
    10141 tatcattacc aattccatat ccaacacata ctttaatatt tgtactattt tcaatagatt
    10201 cttttatata acatgcagta aaatttttag ttaatgattt aatcgtttca catttagtga
    10261 aaattttaaa agaattacta tttttttcaa ttataaaatc ggttaattta tcttttttaa
    10321 tactatttaa tattttataa acttggtcta gagtagagtc atcataattt gtatctttaa
    10381 ctgttatata tattacactt ggttgatttc ccttcattct atgtaaatga atatctttta
    10441 ttaagttatt aaaagtattt tttaataaat ctatatcagg gtatatgaaa tgaaagttta
    10501 ctcctgcatt ttgtaacata ggaacaatac tactaaaacg agtagtagaa aaatcgattt
    10561 tcccttcatt ccatagatta atatgttttt ttgcaatctt tttttcaagt tttgctatgt
    10621 cagataaact cattttagat gcattttcat caatactatc cattaagtct ccaaatgtgc
    10681 catttgataa ataatatgat atatcttttg gattatctgc ccagtctgtt aagtcaaagt
    10741 atgctctaga aaaatctaat gtattatatt taaagataag ctttagaaac atatcatagt
    10801 aactttgtaa gtcagtacca
//
LOCUS       DAEQJM010000098        10684 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.100, whole genome shotgun sequence.
ACCESSION   DAEQJM010000098 DAEQJM010000000
VERSION     DAEQJM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.100"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..656)
                     /locus_tag="KRQ43_003340"
     CDS             complement(<1..656)
                     /locus_tag="KRQ43_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH2743677.1"
                     /translation="MKKDTSHIIKRAEHFQVILIGEGLMVGAVAGLIVLLYRILLGQA
                     GTWLSQILKFVEGSTIKIIAWFAVLAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKI
                     KQVWWRVLPTKFIGGFLSLMGGLALGREGPSIQLGAMAGKGISRALDRGKTEEKFLLT
                     CGASAGLSAAFHAPLAGVMFSLEEVHKNFSVSVLISVMTASLTADYISANFLGMESVF
                     "
     gene            complement(843..1352)
                     /locus_tag="KRQ43_003341"
     CDS             complement(843..1352)
                     /locus_tag="KRQ43_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH2743678.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLE"
     gene            complement(1427..1840)
                     /locus_tag="KRQ43_003342"
     CDS             complement(1427..1840)
                     /locus_tag="KRQ43_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH2743679.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNSDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2277..2936
                     /locus_tag="KRQ43_003343"
     CDS             2277..2936
                     /locus_tag="KRQ43_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HBH2743680.1"
                     /translation="MDEKILELLQEIQGNISNMQGSISGIEGTVNGMQGNINYMQGNI
                     NYMQGTISDMQGTISDMQGSINGIEGTISDMQGSINGIEGTISDMQSNINDIEGTISD
                     MQGSISSMDGTINSMQDSITDMQGEIKEVNSRLDNMEPDIKDLKTGQVETSSRLDTIQ
                     SDVTEIKSDVKINRNTLDTVIKHTSSLVEDTSDIKNDLNNIEIVTSKNWNDIAKLKSV
                     K"
     gene            complement(3543..3722)
                     /locus_tag="KRQ43_003344"
     CDS             complement(3543..3722)
                     /locus_tag="KRQ43_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH2743681.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(3947..4480)
                     /locus_tag="KRQ43_003345"
     CDS             complement(3947..4480)
                     /locus_tag="KRQ43_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH2743682.1"
                     /translation="MQYISYYHSPIGNILLASDNVGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGEEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     HKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            complement(5298..5870)
                     /locus_tag="KRQ43_003346"
     CDS             complement(5298..5870)
                     /locus_tag="KRQ43_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH2743683.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGSCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(5932..6195)
                     /locus_tag="KRQ43_003347"
     CDS             complement(5932..6195)
                     /locus_tag="KRQ43_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH2743684.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDLYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(6195..6416)
                     /locus_tag="KRQ43_003348"
     CDS             complement(6195..6416)
                     /locus_tag="KRQ43_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH2743685.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYSNPKNRVRAKKGGNMY"
     gene            complement(6935..7471)
                     /locus_tag="KRQ43_003349"
     CDS             complement(6935..7471)
                     /locus_tag="KRQ43_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBH2743686.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENKDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(7489..8802)
                     /locus_tag="KRQ43_003350"
     CDS             complement(7489..8802)
                     /locus_tag="KRQ43_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HBH2743687.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEENIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            9138..9578
                     /locus_tag="KRQ43_003351"
     CDS             9138..9578
                     /locus_tag="KRQ43_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH2743688.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLETQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVSLTPKA
                     KELWVTRYTCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(9763..9951)
                     /locus_tag="KRQ43_003352"
     CDS             complement(9763..9951)
                     /locus_tag="KRQ43_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743689.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
BASE COUNT         3748 a         1805 c         1194 g         3937 t
ORIGIN      
        1 tggaatacag actccattcc taggaaattg gctgaaatat agtctgctgt caaagatgct
       61 gtcatcacag aaattaaaac agatactgaa aagtttttat ggacttcttc aagtgaaaac
      121 ataacacctg ccagtggtgc atgaaaggct gctgataatc cagcacttgc cccacaggtt
      181 aacaggaatt tttcctctgt cttccctcgg tcaagagctc tagaaatacc tttacctgcc
      241 atagcaccaa gctgaatgga aggaccttcc cttcccaaag caagaccacc cataagtgat
      301 aagaatcctc caataaattt tgtgggcaac actcgccacc atacttgttt tattttccct
      361 gtcatttccc cctcaagctg agggatacca cttccagaaa tcattggctc ccagtccacc
      421 aactttgata caatccacgc aagtactgca agtactgcaa accaagctat tatttttatt
      481 gtagaacctt ctacaaattt taaaatttgg ctaagccaag taccagcctg ccctaaaagt
      541 atcctgtata aaagcacaat caaaccagcc acagccccaa ccataagtcc ttcaccaatc
      601 aaaattacct gaaagtgctc tgcccgtttg ataatatgag atgtatcctt tttcatactg
      661 ttcctccttc atccaataat tctacacaat ctgaacctcc aatgactaaa gtcatgagtg
      721 tgtacagata ttttttaatc aacaaaaata gatttttatt tactaaatat aagaaaataa
      781 ttgttcaatt tctcaataaa tgtaaattta ttcttttagg tatttattct ccacagtcgt
      841 gcttattcca gcaaaatatt tattagttct tgctttctct gtgtatagat tttacgattg
      901 tcctcaaact gtaatgctaa tttttgttta tgactatcat agagttttgc tttgtctgta
      961 aaagtattta gataatctcg aaaattgata taattattcc atgcgacact attccattca
     1021 acaacatgaa tatggtgagt acgagtattt ttctcaaaat ctcccatagc aaaaagtaat
     1081 tgttttggta catcctgacc tcgaaaaacg attccacatt gctctaacct ttcgaggtat
     1141 aatttagctt cctctaaaga agcaacacct acaacaatat caataatagg ctttgcgcta
     1201 atactgggaa tagaagtgct tccaatgtgt tgaatatcaa tggcagtctt atcccatata
     1261 cttttcaata atataatgac atcttttgca cttttatccc atatcatctg atgttccaat
     1321 aatttaacca taccacattt taaacctatc actatatacc acctcaatat aatccacctt
     1381 tatatatata ttacaatttt ttctatcttg ataaacagtg atctagctat ttcacttttt
     1441 cttgacactc gctacattcc ctatcatgaa tagatataat tcctccacat ttagaacaag
     1501 tatatctctc cttctgcttt tgcataaact tctctaaacc gtactgctga acaaatttac
     1561 tattttccat aaggcttgct tgatatctct tgttataact tttttcaaga ttttttatga
     1621 gtttacaagg aaaattgaaa cattcaaaac aataaaacaa ccctttttga cagacacaat
     1681 cctttatttt acacttacgg cagtgttctg gctttcctgt atcgctgttc aaacaaccag
     1741 cacatggctt tttgtgataa caatgcttat agcaaaccat acaattcatt ccacaaggag
     1801 caaacataat cgtatcaata ctctcttttg gcattttcat aacattttac tcctttcaaa
     1861 aatccaattt gtcgaattgt tatatattca tattgtaaca taaaaaatag ctaaaaaatt
     1921 catgcacttt cattgccaat aaattttcaa ggaaatatga aagtttaaaa ctaagaataa
     1981 aaagaaataa aaaggaagct actaatcaaa atattcaaac acaagtaatc aattatgata
     2041 ttaccagcag ttttaaatac aaatataacc acatatgcct caaaaacact tattatagta
     2101 tcttagacac ttagacaata cacaagattc attaataaaa aagttctcaa tatagatata
     2161 tttaaccatg ttttgaatag cagataatta tatgattaaa aattaaatat gacatagcgt
     2221 ttgtggaata taacacctaa attatgttat aataataaaa caggagtgtg atagtgatgg
     2281 atgaaaaaat attagaatta ttacaggaaa tacaaggtaa tattagtaat atgcaaggta
     2341 gtatcagtgg tatcgaaggt actgttaatg gcatgcaggg taatattaac tatatgcagg
     2401 gtaatattaa ctatatgcaa ggtactatta gcgatatgca aggtactatt agcgatatgc
     2461 aaggcagtat caatggtatc gaaggcacta ttagcgatat gcaaggcagt atcaatggta
     2521 tcgaaggcac tattagcgat atgcaaagca atatcaatga tatcgaaggt actattagcg
     2581 atatgcaagg cagtatcagt agtatggatg gcactattaa tagtatgcaa gacagtatta
     2641 ctgatatgca aggtgaaatt aaagaagtca atagtagatt agacaatatg gaacctgata
     2701 ttaaagactt aaaaactgga caagttgaaa ctagtagtag acttgataca attcagagtg
     2761 atgttacaga aattaagtca gatgtaaaaa ttaacagaaa tacattagat acagtgatta
     2821 aacatacctc ttcattagta gaagatacat cagatattaa aaatgattta aacaatatag
     2881 agatagtcac atctaagaat tggaatgata ttgctaaatt aaaatcagtt aaataatata
     2941 ccatagtaaa aaatacctga aaatttcaca tacttcttta aagttatacc aaattttata
     3001 cagaaatact gattatccga caacacactt tacttataaa taatttatta aaaaatactc
     3061 attttatcct aaaattaaca cgactaaatg agtcttgata taataataaa aaataaggga
     3121 gattgaacac taaaaagttg tgtatctccc ttatattcta taatatagtt atataatttt
     3181 tcagcctaaa ataaaagtcc atctttgatt aaaacatatc cccttatcac ttataaaagg
     3241 ataaaatctt gttttcattt ttccatttat atcttcttgc ttaagagtaa taattttttc
     3301 ttttgatact ttaagtgttt ggttaaattt aaccaatcga ctaagttttg ttcaacatct
     3361 atttttcata ttttccaata cttaatctat tttttataaa taattctttt atttctaact
     3421 cacttacatt ttttacataa aacgaagcat ataaatttca accttatctt gtatggttct
     3481 taatacttaa tgagtagctt aagtatcaat cattataaat tttcccctta tatttaacac
     3541 tcttaccatt tccaaaatat acaaaatata ttttgaacat ttgtacaatg atgaaataca
     3601 atacatgaaa atacaatatc ataactgtta tctaaaaata gaagttcttc aacataacct
     3661 ttcacaaaga acatattatc taagtatttt ttgtctgctc cttgttttcc tgtttgtagc
     3721 atataaatta ctgcatctaa acatataact actcacacga aaaaagaaaa taaacttcca
     3781 aaatacaagc tctaaaacta cctctaaagt tatataatgt ttactaggaa taaggttgta
     3841 taacatatag tttaaagaat agttttttaa aattgcaagt tattgctttc aaaattagat
     3901 gtttatatat caaataaatg attaagaatt tctaaattta atggctttat aatgcactcc
     3961 ctttctttgg gataaaataa tgttgcacag atactttttc taaagataac aattttattt
     4021 ttctatcaat tccaccagca taccctgtca aactcccatt tgttcctaca acacgatgac
     4081 atggaacaat aatagagatt ccattatgcc ctactgcacc accgattgct tgtgctgaca
     4141 ttttagatat tcctttttgt tgagcaactt tatgtgcaat ttctccataa gtgattgttt
     4201 taccatatgg tatttgttgt aaaattttcc acactgtagt ctggaaagga gtacctacca
     4261 tatggagtga tggtgtaaaa ttgggctctt ctcccgaaaa ataaatatct agccatttct
     4321 ttgtctgctc gaaaattggc aattcttttt cttgatgttc ttggtcaaga ttataagcat
     4381 aatacttttg attctcaaac caaagaccag ttaacccaac attatctgat gctaaaagaa
     4441 tatttccaat tggactatgg taatagctaa tatattgcat acaattcctc cttatattct
     4501 gaaaacttca ctcaaatcat tagacacttc ttttctatct gccattatgt aaaaacatac
     4561 taatataatt tccttctgac tacactttcg ttataatatc tatcctcata tcatattagt
     4621 tttatattta cctgaatctg ttcatccttt ttttcctttc cctttgatgg atataaaatt
     4681 catacattta agcttcctac tgtattaact tttatagaag tgtatattat aattttatca
     4741 ctaaatagac aaaaaaatat cgatataaca tcaagaaata ttttactgag tttcgcttat
     4801 taaaagcaac tgaatttcta aagggtacag atgagctaat aagtgatatt gatataaaag
     4861 ttgtttttca ttaagtaatc tattttagta aatgttttaa agaaaaaacg ggatattctc
     4921 caaaagtgta cagaaatata aaaaaagaga tatgattttt tatttctttt gattatccaa
     4981 agagtaaata aaaaatattg taaaaaactt actaacaacg gcaatgcttt gaactatggt
     5041 aatactttga acttttgatt ggactttttt tgctaaaata atatatttaa atagcaaagt
     5101 aatctgttta atcaataaaa aataagagat aaaagaaatc aactaaaacc tttacctctt
     5161 attttgatag tttatcagag ctaatattta cactcttttt atttttgata cttcattaaa
     5221 aatgatgctt attctctttt catttttaat acttcattaa aattgatgct tactctctat
     5281 tcacttttaa tacttaatta gaactgatgc ttacactctg taaactcata aacatccatt
     5341 aatgcttcac caaatctttg atagtgaact acttccctct cacccaaaaa tctcaatata
     5401 tctttcaaat cagggtcatc agttaaattt attaattgat agtacgtagc caatgctttt
     5461 tgttcagcag ccatatcctc atgtaaatca gttaccgaat cgccaaagac attaatataa
     5521 cttgtagtaa agtttactcc attagaatct actggttgaa gaccatgtcc aaaattagca
     5581 taattactac caagtccagc agccttaagc tcttccggag tacaactgcc tattaattga
     5641 tataacactg aagaaattat ctcaacatgg gccatttcct ctgtacctat atcagttaaa
     5701 agtgcgcgag attttccagt tggcatagta tatctttgtt gaagatatct agttgcagct
     5761 gccaactcac cattaggtcc tcccaactga gtcatgatat attttgccat tctagggtct
     5821 gcttgtctta tgttaactgg atgttccagt gttttttgat aaatccacat attatcttac
     5881 tcctccttaa tatatattta ataataattc taattttaaa acttaataat tttatttata
     5941 aaatgatttg tcccatggcc aaggttcaga tatccatgac caaggatatt cacttgattc
     6001 atatccaaaa ttagttaatg ctccatattt agattcataa tcacacacag cttgtgtaaa
     6061 tttatcgcag tatctattgt ataaatcaag agctttctta tcccttggat tgttatctaa
     6121 atataaattt aattctatac aggcaaattg atattctgaa attctctcta aaagttctct
     6181 tctatttaat gacattagta catgttaccc ccttttttag ctctaactct atttttagga
     6241 tttgaatata gccaatcatt atagttattt gactctatta aatctaattc aggaaataaa
     6301 gtacctcttt ttaatgctgt ttttggattg tatgtgtcat cataaatttg acgattgatg
     6361 tatggtctag caaattcaca acaatagtct tgtttatcct cttttaaata tcccattaat
     6421 tatcctcctt aatttttaga attttaaaat agcattattt ttaaaaattg tatacttgtt
     6481 ctatattata gtcagtagtt ttaataggtc tttaataaga ttaaataatt aaataagtat
     6541 ctttttttgt tcttatttta cctataaaaa ttttcctaat taatctttca taaatatcta
     6601 ttttaaataa ataatataga gtttatacaa ttttttataa cttaattact atttactata
     6661 tattattcat ttttaaataa aatgtgatta ttttttatta aaaacgatat aaatatacaa
     6721 tttaatacta tttttaacaa ataaatttat attaaaatac attaatttat atagttttat
     6781 ttattctaaa agtataatta taaaaataaa aaaagaatag gatatttttc ctactctttt
     6841 ttctgtgctt atatataata ttaaagctct ttattttcaa tatatatttt aaattttctc
     6901 tttttaatat atctttttct tttaataaat ctctttaatt ttcttcttct atatcagagc
     6961 caaagggaat ccatgcatta ccaaactctt tatctttaaa taaataagct aatccagtta
     7021 tttgcttcaa tctaagaatt tcatcaactt ccatacccag gtgctttgat atccattcat
     7081 cagattttcc aatttcacaa agttcagtta taattttact cattaaatcc acattatgag
     7141 aacctcttgc acgattgtgt cgaatagtac ttgccattct ttcatcaaga gatttatcaa
     7201 ttactgaaac aggaagaagt ccgttttctc tatcatatat atccttattt tcaagcatta
     7261 ctctatatct atgaaaacca tctacaataa tatacttatc cttttcctca ttataataac
     7321 agacaattgg cattgtatac ccatcttctt ttatactttt atacaacaac tgcatttctg
     7381 gtggggctac tgcatttgga ttatagtcgt tagattctat cttttcgatt ggcactgcga
     7441 tgattccata tacaggactt ttatattcca tagcatctta actcctatct aatgaatttt
     7501 ttcatatttc ttcttaatat attccgttct aattctctgt tcttttgtag gaccaaatcc
     7561 cataaatcta cacatatggt cattttttaa aatacaataa cacattcttt tccaacttgg
     7621 tatatctttg gtaaatttaa tatcatccgt atcatcaggt atatcatcca aaaatatgac
     7681 tctactcttt ttatcttttg tatgatttga aactccattt aattctattt tataaccttt
     7741 tctcaacaat tcacgtataa ctatttctga caaaccacca cctgtattct gccaaaactc
     7801 aatagatgtt gaaaattttt taatatagct attccttata ttttcaggta aggtatcaag
     7861 caaaaaatat gtgaaacttt tccatgtgtg tccatatggc aatttaacac tacgatatcc
     7921 catagctttt gtttttccat aaatagaagt aaaattaact ccttgtactc tagcaaccaa
     7981 tttcacccat acatctgggt ccaatattct gtataaattt aaactctctt ttgctgaatc
     8041 attaaaaggt gatgccactc tcatttttct tggagctact ccagctttat agaataagtc
     8101 ataaatttta ttatagtcat aatcaaattt atagtgggct aaccatatat cttctatttc
     8161 ccaatcatat ataggagatg ccgtccagac atttttaaat tccttagtta tccagcactt
     8221 tcctttatat ccatgctgtt tattcacaat agaacaataa cgttgtagag attctgctgc
     8281 tcgtgttcct aataagcaaa caacttttgc accttcatgt atatctctaa tccatctacc
     8341 aaattgcttt gccaaacttt cttgtctcat tttatactta taataagtaa aaggattatt
     8401 tttttgattt attatgtatt ctttgactgg catttctctt acccataatt cttctttctc
     8461 atcatcccat ggataccaat acatttcata atttcctaca gcagttcttg tagccattgg
     8521 taaacacacc caatatggtt caatatcttc aatattctct tcaaatactt tttcaacata
     8581 ttcagtagtc aaactatatt gagcctcaaa atcttgatga aatactccta ttttggaact
     8641 tatattattc tttctcttat aatccaaaac taaatttagc agtaagccac tatcttttcc
     8701 tccactaaaa gatacataga tataatcaaa ttcattaaaa agataagaaa gtctttcttg
     8761 aaaagcttca aatacatcgg attctaaata tctcttatcc atttgaatta tcccctttca
     8821 attagaagtt tataaaacct tacaatacaa tattattatg cttttttagc agtaatcagc
     8881 ataaattata cattatttaa atacacaaat ccaactaaac acatataatt ataatgtaat
     8941 tatacttttg tattataaac tatattttat cattatttta catttttttc caatatatat
     9001 aaatatcata tttttctatt agctaaaaat aattacttta tatttttaca tgttagtata
     9061 ataagacata aaaacttgac atactgttgt cataattact ttgctataat taaaagtaaa
     9121 aatggaggta aattataatg tatgaacgta tgcttgataa aagcaataaa ccctgtttgt
     9181 ctcaaataat agaatatata ggtaaagatg gatatgcacg attgtgtaag ttggaaactt
     9241 acttggaaac tcaatataat ttatcaagag aacttcgatt tccttttgga aacaattatg
     9301 gttggggtta caaatatagc cataaatctt ttcatttatt ttatgctttt tttgaaaaag
     9361 gtgcatttac tgttctgatt cagataggtg acaagcaagt tccagcagta gaaaaaacgt
     9421 tggtatcttt gacaccaaaa gctaaagaac tctgggtcac tcgttatact tgtggcaata
     9481 atggaggttg gattaagtat cgtattttag aagatgcaga cttacttgat attattcaat
     9541 atataagagc aaaaaaatct ccacctaaac aaaattaact tttatttttt gtgatttaaa
     9601 tatagtgtat ataaattcca ttctttccat attaaaaaaa taatataaaa aatatctatt
     9661 agtatatctt atttagtatg tcttattcta ctttttacag ataattaaaa agttttatca
     9721 taaataaatc ataactaaac atcctagtaa atcaaaattc atttattctt ttttattaga
     9781 atttttgata acagtcccta tacatatgcc aattatcatt ccaaaaatta gaccataaca
     9841 cattgtgata cccacatttc ctttagaaat acctatagca caacctatag ccattccaag
     9901 tatcatgcct ataaacatac atataataac taaattgttg tttttattca tagtttttct
     9961 ccattcaata tattttaaat tgcctagctc gccttcttag cttaaaacaa agaaatataa
    10021 attaactttc tttcattcta atatctgctt gtataaatgt caaacaacac atttcttgtc
    10081 ataacctcct ctttttgaag taagtacaat ctcccagaca caataatatc aatttcctaa
    10141 aaccatttaa gtaactttta tatttacata atatttacaa tcataaacta tattgttatt
    10201 catttataca tcataaacac tccctcctaa tcattattat acttaaaata atgttcattt
    10261 ataataatat atctaacgca ctttaattga aaaaactaaa actttgcctt tcattcccat
    10321 atataaataa gtatactttt tgatgctcta ttacaaatca actaaattaa ttgatataaa
    10381 ttatcatttt ctgttgaaaa taccatttac acatgctata cttaattgca taaatggtaa
    10441 taaatgtcat atgattttac aaatctatta ataacaatta ttacttttac tgtattttaa
    10501 agtttttgga ctaaatatca agaactttct aaaatacaaa gtacaaaaaa tttatataag
    10561 ttataaattt atatgaacta gataagctca aacaatatgt tatgtataaa ctgtgtagta
    10621 ttcggttata aatttatata aattatataa gctatataaa gtattacctc aactatataa
    10681 gcta
//
LOCUS       DAEQJM010000099        10318 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.101, whole genome shotgun sequence.
ACCESSION   DAEQJM010000099 DAEQJM010000000
VERSION     DAEQJM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10318
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.101"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            263..658
                     /locus_tag="KRQ43_003353"
     CDS             263..658
                     /locus_tag="KRQ43_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743690.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNNIKCEEIKDNVIEEKNNTCTTE"
     gene            701..2800
                     /locus_tag="KRQ43_003354"
     CDS             701..2800
                     /locus_tag="KRQ43_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBH2743691.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEISVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLKKDATEILVPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGEAMVNQASLTGESLAVNKKEGSYIYAGTGIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNHSIAVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKKDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLREYGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVSGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYY"
     gene            complement(3025..8235)
                     /locus_tag="KRQ43_003355"
     CDS             complement(3025..8235)
                     /locus_tag="KRQ43_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBH2743692.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRNFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDRQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKTQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLCIPEGIYSINVSGK
                     DAEKLVGEGSIYDGMNGRNGNNAGTSGDILLSFKEIEKRGELKLYVDGGRGGNGQDGK
                     RGDTGITGEAGENAKIGSKKESKEFAKVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKASLLKGAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSAPIDDSDRNYYYFDRYVFNHASNENQVADDGEKLNALYEKHKDWTISKREDSGLV
                     GAEGKDGRSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFIGEKKNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKDELENK
                     MLSVNAKMNLLIQEIIKMKEEEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYAEKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSGSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYIDI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSESIDILKSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIC"
     gene            complement(8250..>10318)
                     /locus_tag="KRQ43_003356"
     CDS             complement(8250..>10318)
                     /locus_tag="KRQ43_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH2743693.1"
                     /translation="EADILDSRLTKVLDLFQQLNMCLHKDNFRGSITFFISKSFLGRT
                     EKQIYNVIKRKYEQLCENLDSNIEEKAWLFEELLKDNGKNIHLCKPLESDEREGLLKQ
                     VLELDEVKDKTSAFQYPISADARLVLDTLIKEIQNNIVSSLEDYVKAYTEDFISIIGS
                     ITMIQEIAKYDEVVKVFKNWLESTTTLTIERFINVLAKQSGLFLQDSCMELQNKIKGN
                     LDIIDALSKYTEHGTGEILLPSVHMEFIIEKASKKIMEQNFIIIRKNLEKVLVSYEVQ
                     KQVFTLPNREKLMEVANKKDYVYSVSDFNSILTNVTVTQNEELEDSITRLSAYGEEGN
                     EIIREFIGKYILNPFIVKTININDKKGIEIRALIPNLVISSVLEYFKNRKVDDNVSTF
                     MFFAKDTIYMDDNLGMDFASEKNIILACNNLDVGSNVKINVSGKSGELVDSSMYGKNG
                     EDGRDAGNIYLYIKEEIRNYRLTLIANGGNGSKGIDGKNGETGDSGSNGADAGYTSSF
                     HGQMFKGYFAKGTSGKKGDKGGAGGNAGRGGNAGNKGNIYFISDSEEQKNRIINHCDI
                     TVKDGEAGPNGRPGSGGYGGSGGYHGYNTLSFSPSGIDKTVYYTGYFTSWDYKLDSII
                     KYHIEFSGGSWNEGKTGPAREYAEYGDRGDDGGFNAPNTKLSTAVSKVEENLIKEKYQ
                     GYCSEI"
BASE COUNT         3329 a         1926 c         1210 g         3853 t
ORIGIN      
        1 tcaactatat aaactacata tataaattac atacataagc tagatatata aactagatat
       61 ataaactgca tatataagct atataaaaat tatttcaact atataaacta cacatgtaaa
      121 attcatgtaa atttactaat ataaatcaaa taaaattact aaactctcta aactaatttt
      181 gtaaaacata ctctattttt aacatttgtt accttataca taagtataaa caaaatctaa
      241 ctaaatgaaa ggataatgta aaatgaatat tttaaaaatg aaaaaaacag gaatattttt
      301 aggaggagta ctttttggta ctgtaggtgt taagatactt tcaagtgact gtgtaaaaaa
      361 aacttgcact cgtgcaacag caggagcatt gaaagttaaa gattctgttc ttgaaacaac
      421 tacgaaaatt caagaaaatg tagaagatat tttagctgaa gcaaaagaaa tcaacgagca
      481 agaagactta tctacatcta aggtaaacgt tgtacaagat actcttaaat gcgaacaaga
      541 agttcttaaa actgaaacta taaaaactgt agaagatact aattctaata acattaaatg
      601 tgaagaaatc aaagataacg taattgaaga aaaaaataat acttgtacaa cagaataaat
      661 ttaatgatta ttatgattaa taatatcagg aggaagtaaa ttgaattttt atataaaaca
      721 cgaaataaga ggtcgtatac gctttgactt acaacttggc aaattaaaca acaagcagtc
      781 cgatactctc ttatattatt taacttctat aaatggtatt accaaagcaa aagtttacga
      841 tagaactggt gatgcagtca tttattacac tggtgaaaga gaatacataa taagagaaat
      901 cactaaattc agttttaaca atagcaaaat agaaaaccta gttcctgaac ataccagcag
      961 ggaattaaac aattattata gagacaaatt agcaaataaa ctgctagtca aaagtatctc
     1021 caaaatattt tttccaaagt ccttaagatt ttttttaatt ggacttcatt ctataaaata
     1081 ttttaaaaaa ggtctctctt ccctactaaa taaaaaaata gaaatttctg ttttagatgc
     1141 cactgctata ggtatttcta tttttagaaa agatatcaat acggctggtt cagttatgtt
     1201 tcttcttggt atcggtgagt tattagaaga atggactaga aaaaaatcta tagacgactt
     1261 ggctcaaagt atgtcactaa acattgaaaa agtatggtta aaaaaagatg ccactgaaat
     1321 actagttcca atttcagaga taaaggaagg agatttagtc agtgtaacta tgggaaatat
     1381 gattccattg gatggagtta tagtatcagg agaagcaatg gtcaatcagg catcacttac
     1441 aggtgaatcc cttgcagtta acaaaaaaga aggctcttac atatatgctg gaactggaat
     1501 agagcaaggc aatattgtta tgtgcgtcaa ggaaaaagct ggtactacta gattccagaa
     1561 aatagtaact atgattgaag aatctgaaaa actaaaatct tctgtagaga gtaaatttga
     1621 acatctagca gatacattag ttccatacag ctttttagga agtatattaa cctatgcaat
     1681 tactagaaac cctataaaat cactctctat attgatggta gatttctctt gtgcattaaa
     1741 actctctatc cctatttcag tactatcagc catgagagaa tgtaacaatc acagcattgc
     1801 tgtaaaaggt ggaaaattcc ttgaaggtgt tgcatgtgca gatactattg tatttgataa
     1861 gacaggcaca ttaacaaaag ctcaaccaac tgtttcagat ataattacat tccaaaatta
     1921 taataagaag gatatgttaa gacttgcagc ttgcttagaa gaacacttcc cacactccat
     1981 agcaaatgca gtagtttatg aagctgaaaa acaagggctt agtcacaaag aaatgcatac
     2041 agaggtagaa tatattattg ctcatggcat ttcaacaaag gtcgatgata aaaaggttgt
     2101 aataggtagc aaacattttg tatttgaaga tgagaagtgt actatcccag acggtgagga
     2161 ggataagtac aacaatctat cagatgagta ttctcaccta tttatggcaa tatcgggtaa
     2221 attatcagca gttatttgca taaatgaccc tttacgaaaa gaagcaaaat atgtaatttc
     2281 aaatttaaga gaatatggaa taaaaaagat tgtgatgatg actggagata gcgaaaaaac
     2341 agctaaatct atagcaagta aagttggtgt tgatgaatat tattcagaag tcttaccaga
     2401 agacaaagcc aattttgtta aaagtgaaaa actaaaaggt cgcaaagtaa ttatgattgg
     2461 tgatggaatc aatgattctc ctgctatttc agaatcagat gtcggaattg caatgagtga
     2521 aggtgctgaa atagcaagag agatttcaga tattaccata tcagcagata atttgaataa
     2581 tttaatcgtt ttaaagcaga ttagtaataa gcttatgaaa agagttgatt taagttctaa
     2641 gtttattatc ggctttaatt taggtctgat tttacttggc gtaagtggat ttgttagacc
     2701 aagtacatct gcctttttac acaacgcatc tactgttgga ataagtttaa acagtatgac
     2761 aaatttattg gaaaacacca atacttataa ctactattaa tccccattat ataaaacata
     2821 tgtatataaa aaatttataa ttcatctttt aaaaagaaac tgtcttaaaa ggagcttttt
     2881 tctaatcaaa attatataaa acatatttta caaattttaa actcaactta tttctatttt
     2941 ttacaaaaag gagatgattc aaattttcat tttgaaacat ccccttttgt aaatttcttt
     3001 aaaacttata tattaattat attttcaaca aataattgta ttttcaacca atctttcttc
     3061 atagcatttt aaatcatttt gctttagata attaaattca gactctacat aaataccaca
     3121 gcctaccaat tcaattgtca aattaggtat attttccttt agtatactag tctgctcata
     3181 aataattctt tccaataaat caacttgtaa tatagaaaaa tgcttcataa tctccccatc
     3241 actatctata tctttcttga tttcatacca actctttgac aaaattccct tcaaatcaat
     3301 ataccctaga ctcttcaata tatctatact ctcgctccat gcatacttac taggtttatc
     3361 aaagtatgat tctagtttct tcttctgctc atttgtaagt gaatcataag aaagcttctt
     3421 attaaaatgt gccttcaaag aaatcttagc catagaatat ggacttctac cagagtttaa
     3481 tcctgcattt ttgaactttt caattccttt atcttctact gaagaccata ttgagtttat
     3541 tgaatctgaa tcattgtatt taacatcaag accatgtgta atatctatat agttttgtgg
     3601 aaatacatat tgataataga catctttttt atcatcatat agggagaagt atccactatc
     3661 atataaatga atatgcacct ttacttttaa actatcctct aaaatatttc gtctaaggtt
     3721 cgggatattt gcatacatgg ttacatattt tatggcatca aagtttttat ttaatggaac
     3781 ttcaaaacta atttcatctc ctgtcaaaag ctttttcact tcttcttcat tacaatcata
     3841 tagagaatat gtattttcaa atcccacacg tgatttccca tctaaactgc ctgttaatgc
     3901 taccttcaaa atatggttat ccgttttttg ccattggtaa gcatcttggt caagaaactc
     3961 tctaatctgt ctattttgct ctttcgcctg atttataacc tcgttttcat cttctgtaat
     4021 acctacatgg catctattta agatatttac tatattgctt ccaaatggaa acgtccatag
     4081 ttgaaaagct gctgcctcaa cctgacacaa atatctaacc tgatttaatt caatttgatg
     4141 gataagtttt ttctgatatt cattcatctg attaccacta cctgacattt gataaatcaa
     4201 ttctcccatt gcaagattat cttttttctt atcaatctta tcagtaatga taatttgagt
     4261 ttccatcata tcctgtactt ttttaaatat tatagaaatc tcctctgaat tttccatttt
     4321 taagcttcca aactttgtgc ttaattcagt taaaacttcc ttcatcttta atttacttat
     4381 ctcattttca aaaatatctt gatttttaac tgtactatcg aatttttcta caaatggtat
     4441 aacagattct ttcaaagttt tatctttaaa ttccaccatt tgagtattca attcatctaa
     4501 tttcttaata ttattttctt tatctttaat tgcctcttta actacctcta ttttactctc
     4561 aaaactagat tttacattaa gacaattatt aacaccacta atcgcagtat ttataagaga
     4621 acaagcagaa cttccaatac tcaatgcatt tttaatttta gatgtctttt gctgtctttc
     4681 aatagcttgt ttacttttct ctagtgcagc taacttatct ttttgctgtt tattattgta
     4741 atttgcctcc aacataccta tttctttttt ctggattttt gtgtaaattt ccttatactc
     4801 gctttcactt aacccctctt ttgctctttg aatatcgtca gctttttctg catagttatc
     4861 atcatctata gacttaacta taatctcctt aatttggtca aatttagttc ttctttcttc
     4921 atcaacacct gccaaattat aagtcatttt atctaaagca ttttttctat cttcacttag
     4981 ctgttctcca agtacaaatc tcataccatc agaatccaat ttaaaatctg aaaaatcaac
     5041 catcctgtta gtccattggt attcctcttc tttagctgaa agattttcct tcaaagattt
     5101 tgcactgtca aatgccccta gacaagcttg accaacacca ctaaatgcag tcagtaaact
     5161 caatgcgctt tgtattccag aaagaattaa ctgtgttttc atttgttcct caagttttgc
     5221 ctgtttcttt tttagttcct ctatgtcttc ttgctcctct tctttcatct ttataatttc
     5281 ttgaatcaac aggttcatct ttgcattaac agaaagcatt ttattctcaa gttcatcttt
     5341 taaaacttct atttgttgat ttccagattc aatttgagtt aggatacttt ccttataagt
     5401 attgaaatat ccttctttta actcatcttt ctttccttgt tccaattctc ttaaggtctt
     5461 gtccagataa tctgtcaaag aacgaatatc tgtaacacga tttcctccaa tttcactttc
     5521 ttcaatcatc tgcacataga atgctgtttt ttgttcaagt gcaaataaaa tcatactcca
     5581 ttcgctaaaa ttcttctttt ctcctataaa agattctatt ctatcagact gcatcaattt
     5641 atttataagg tattcataga tttcctttgc ctccttataa aattctttct ttatattcat
     5701 atcatccaga gaaagcactg ctttattttt cttctcaaaa ctatagtact tctgaagtat
     5761 ttctctattt aattgcatct ctattttctc aactgcatga aaaatttcat aaatatgtga
     5821 aagttctaaa atatcagctt ctaaaattcc cactgcacac aacagtctaa gatttctata
     5881 acctttaatt ccagaaaaac caaatctctc gaaaaattca tagaagaagg tatctattga
     5941 caaagaatac tcctgcttta acaattcctt ttcttttaat gcatctccag agcgaccgtc
     6001 ttttccctct gctccgacta aacctgaatc ttcacgtttg ctaattgtcc agtccttatg
     6061 tttttcataa agagcattta atttctctcc atcatctgct acttggttct catttgaagc
     6121 atgattaaac acatatctat caaaataata gtaatttcta tcactgtcat ctattggagc
     6181 agaggtacct atatatctta ttgtttcttc atatatacct ctaattccac caagacctcc
     6241 tgcaccacca gctcctccag agcctccttt tcctgctaga ccatgatttc catctttttt
     6301 acttatagca ccttttaata aagaagcttt tccaaggaga taaacctgtc cagacttgct
     6361 cccaagacct gcatttccac cattacctcc tgtgcctcca gttccacctt gttttccttt
     6421 ttctgctttt accacatagt attttgtacc tttaacctta gcaaattctt ttgactcttt
     6481 tttagaacct attttagcat tttccccagc ttctccagtt atccctgtat ctcctctttt
     6541 tccatcttgt ccatttccac cacgtccacc atctacgtaa agtttaagtt ctcctctttt
     6601 ttctatttct ttaaaagata ataaaatatc acctgaagta cctgcattat tgccatttct
     6661 tccattcatt ccgtcgtaaa tagaaccttc tccaaccaat ttttctgcat ccttaccaga
     6721 tacgttgatt gaataaatcc cttctggtat acataatttt tctgtaagta gtacaatatt
     6781 cttacctgag aagacttctt tctccatatt acagtcaatt ttcaactcac aatctccata
     6841 catatatata gatgacaaaa tattaagttg ataaccagat attattttag tcaaatccga
     6901 taaattcact ttaggtatag gaatatatat agaaagtaca ttttctttct catatgattt
     6961 tatatatgta caactttgaa tcttctctat cctatactct gcatcttcaa gctttttggc
     7021 ttcttcttcc ctatattctt cttctgctat ccaatatttg atatctttta atgtatcttc
     7081 taaagtattt tttagcaatg attttaacaa ctcacttaga ccaacaatat gagtctcact
     7141 acagtagcta tttaactcta aaagaagacg tgtttcttct aatatattca ctttctgtac
     7201 gccatcacca tatgaaagtt cttgtacaaa ctccataagc tctttcatat tattagtcct
     7261 actacataaa tctgtataca tcttatctaa ttgagtcttt ttatccttta gactatttat
     7321 agaagataga atggaaatag aatcttccat accttttttg acactttcta tataaggaac
     7381 taaaagtttt tctaggtctt tataggttac atcaacggct ttttgtattt ctattttaca
     7441 agaagcagta agcatcaatc ccaaatctgt tttttcaaat gtttcaggta gatttttcat
     7501 ttcatccaac aacttttctg gctgtctatc tagtggatta cataatttaa tagatacacc
     7561 atctgataat gctacattta ataagtacac taattcctta caaccgtcgt aatctttctc
     7621 ttgactatct aggtcttctt ttgctttttc caatatattc cttatttttt cttctgttac
     7681 attaccgatt agtgttttag gtattttatt gataagaaag aagaaatttt ctttatactt
     7741 tgcataatca ccaagcatat ctttcaaatt tttgcctgtt tctatcaata atgtatgtct
     7801 agagtccagt aaggattgat agtctaaaat aactaccatc cctttcacct ttgaagatgt
     7861 agaaatagtt tcccttacaa gcatagcacc agcaatcata tactctgctc cacggttatc
     7921 aaaaaaacct gggcaatcac ataatgaaaa atttctattt gcaatatcta caacttctgg
     7981 acataaagtc ttagaatata caccatttcc aatttcgaca gctgaatctt ttgcagttat
     8041 atatatttgt ccagtctctt catccgtttt ttcttccatc acgcaacctt ttaaataatt
     8101 tatacaagta ctctttccaa cgcctgaagc acctaagaat aacaaaattg acttttcttt
     8161 taagtcatat tttctaagct cgtctcttcc ttcttccaaa aggtttacga tttcactata
     8221 aagtttattt gccatacatc catccctttc tatatttcgg aacaatagcc ttgatatttt
     8281 tctttaataa gattctcttc tacctttgaa acagctgttg ataacttagt atttggagca
     8341 ttaaatcctc cgtcgtctcc tctatctcca tattcagcgt attctcttgc tggtcctgtt
     8401 ttgccttcat tccaacttcc gccactaaat tctatatgat atttaattat actatctaac
     8461 ttataatccc aacttgtaaa atatcctgta tagtaaacag tcttatctat accacttgga
     8521 gaaaatgaaa gtgtattata tccgtgatag ccaccacttc ctccatatcc acctgaacct
     8581 ggtctaccat ttggacctgc ttctccatct ttcactgtta tatcacaatg attaattatt
     8641 ctattttttt gttcctctga gtctgaaatg aagtaaatat tacctttatt accagcattt
     8701 ccacctcttc cggcatttcc accagctcca cctttgtcac cttttttacc acttgtacct
     8761 tttgcaaaat accctttaaa catctgtcca tggaaactac ttgtatatcc tgcatcagct
     8821 ccattacttc cagaatctcc tgtttcacca tttttaccat ctattccttt agaaccattt
     8881 cctccatttg caatcagtgt taaacgataa tttctaattt cttctttaat atataagtaa
     8941 atattacctg catctctacc atcttcacca tttttcccat acatagaact atctacaagt
     9001 tctccgctct ttccacttac attaattttt acattactac ctacatcaag attgttacaa
     9061 gcaagaataa tatttttctc tgatgcaaag tccattccaa ggttatcatc catataaata
     9121 gtatctttgg caaagaacat aaatgtagaa acattgtcat ctacttttct atttttgaaa
     9181 tattccaata cactactaat tactaagttt ggaattaatg ctcttatttc aatacctttc
     9241 ttatcattaa tattaattgt ttttactata aatggattta aaatgtattt accaataaat
     9301 tctctaatta tctcattacc ttcttctcca tatgcactta atcttgttat actgtcttct
     9361 aactcttcat tttgtgtaac tgtaacattt gtcaaaattg aattaaaatc acttacacta
     9421 tatacataat cctttttatt tgcaacttcc attaattttt ctctatttgg taatgtaaat
     9481 acctgttttt gtacttcata agaaactaaa actttttcta aattctttct tattataatg
     9541 aagttttgtt ccattatctt cttacttgcc ttttctataa taaattccat atgtacagaa
     9601 ggtaataaaa tttccccagt tccatgttct gtatatttac ttaaagcatc aattatatct
     9661 aagtttcctt ttatcttatt ttgtaattcc atgcaactat cttgtaagaa taagccactt
     9721 tgtttggcta atacgttgat aaatctctct atagtaagag ttgttgtact ttccaaccag
     9781 tttttaaata cttttacaac ctcatcatat tttgctattt cttgaatcat tgttatactt
     9841 ccaataatac tgataaaatc ttctgtatac gccttaacat aatcttctag gctagatacg
     9901 atattgtttt gaatttcttt tatcaacgta tctaaaacta atcttgcatc tgcactaatt
     9961 ggatattgga atgctgatgt cttatcttta acttcatcta attctagtac ttgctttaat
    10021 aagccttccc tctcgtctga ttcaagtggc ttacaaagat gaatattttt accattatct
    10081 tttagcaatt cttcaaataa ccaagctttt tcctctatat tactatctaa attttcacat
    10141 aattgttcat attttctttt tataacatta tatatttgtt tttctgttct tcctaagaaa
    10201 ctttttgaaa tgaaaaaagt tatactgccc ctaaaattgt ctttatgaag acacatattt
    10261 aactgttgaa acaggtctag tacttttgta agtctagaat ctaatatatc tgcttctg
//
LOCUS       DAEQJM010000100         9651 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.102, whole genome shotgun sequence.
ACCESSION   DAEQJM010000100 DAEQJM010000000
VERSION     DAEQJM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9651
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.102"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..336
                     /locus_tag="KRQ43_003357"
     CDS             <1..336
                     /locus_tag="KRQ43_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH2743694.1"
                     /translation="KVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKE
                     AGIDSEITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYY
                     GILKSVYGK"
     gene            469..1839
                     /gene="hydA"
                     /locus_tag="KRQ43_003358"
     CDS             469..1839
                     /gene="hydA"
                     /locus_tag="KRQ43_003358"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH2743695.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKN
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            1857..3263
                     /locus_tag="KRQ43_003359"
     CDS             1857..3263
                     /locus_tag="KRQ43_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2743696.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            3335..3781
                     /locus_tag="KRQ43_003360"
     CDS             3335..3781
                     /locus_tag="KRQ43_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH2743697.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            3820..4614
                     /locus_tag="KRQ43_003361"
     CDS             3820..4614
                     /locus_tag="KRQ43_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH2743698.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            4604..6895
                     /locus_tag="KRQ43_003362"
     CDS             4604..6895
                     /locus_tag="KRQ43_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH2743699.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDTKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            6896..8209
                     /locus_tag="KRQ43_003363"
     CDS             6896..8209
                     /locus_tag="KRQ43_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH2743700.1"
                     /translation="MIAIKSKYLISSADEIYTNSAAVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            8245..9330
                     /locus_tag="KRQ43_003364"
     CDS             8245..9330
                     /locus_tag="KRQ43_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH2743701.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
BASE COUNT         3787 a         1039 c         1982 g         2843 t
ORIGIN      
        1 aaagtttctt atgcggttga aaaagctgat tgctatacag gaaatactat agaaagtgaa
       61 agattcttcc caggttggtt atatgacgaa gaagatgaat ttgttcaagc agcatataag
      121 ggattaaaag aagctggaat agattcagaa ataactcaat actcattctg tacgaatgga
      181 agtcactatg caggtgaagc tggaataaaa actataggat ttggtccttc taaggaaaat
      241 cttgctcaca caatagatga gtatatagag caagaacagt tatttatagg aacagaaggt
      301 tactatggaa tattaaaatc tgtatacgga aaataatatt tagttcacaa taaattattt
      361 aaatatagtc tagaggtgct gaatatagca cctttagaaa atacaatttt aaataaagtt
      421 ttacgatact tagaaaatac tttaaagctt aaaagttagg aggtatatat gggaacaata
      481 ctaagaggtg gaactataat tacctctgat aagacttata taagtgattt aaggatagaa
      541 gatgaaaaga tagttgaaat aggaaataac ttagaaataa atggtgataa ggttattgat
      601 gctacaggta aaattgtaat tcctggtgga atagacacac atactcattt tgatatgaat
      661 gcaggttcta ttacaactgc agataatttt gaaacaggaa caagagcagc tatagctgga
      721 ggaactacta caatactaga ttttgcagaa gccaatgagg gggaaaacct actgcaaggt
      781 gtagaagcat atcataaaaa agcaagtgga aattgttatt gtgattatgg ttttcatatg
      841 acaattacat gtttaaataa agatacattt aatcatatgg aaaaacttat ttcggatggg
      901 atagtatctt ttaagatgta tatggcatat gatggcatga aagtagatga tggaacaata
      961 tacagggttt taaagaaagc aagggattta ggttgtatag ttggatttca ttgtgaaaat
     1021 ggggatttac tagatgtatt gatagaagaa aatatacaaa atggtaattt agagccaaaa
     1081 tatcatccac ttacaagacc taacatagtt gagaaagagt ctgtttcaag acttgctgat
     1141 ataactaaat tatctaattc aaaatcctat gtagtccact taagttgtag ggagtcactt
     1201 gaaactgtaa aaatggctag agaaaaaaat atagatatga tagtagaaac atgcccacag
     1261 tatctattat tagaagacaa tttatataat aagaataaat ttgagggtgc taagtatgta
     1321 atgtctcctc ctttaagaaa aaaagaagac ataaattacc tttgggaagg attgtctagt
     1381 ggagatattc aaacagttgg cacagaccac tgttcattta attttaaggg gcaaaaagac
     1441 ttgggaattg atgattttag taagatacca aatggagcac ctggtgttga acataggtta
     1501 gcacttttat atacatatgg ggtcttagaa aatagaataa gtgtaaataa gtttgtggaa
     1561 gttacttcta cgaatgctgc aaaaatattt ggaatgtatc ctaaaaaagg tgagatagct
     1621 gtaggaagtg atgcagatat agtcatttta aatatcaata aagaagaaac aattagttat
     1681 aaaactcaaa aacaaaatgt agattatact ccatatgaag gatttaaggt taaatgtaaa
     1741 gttgaagatg tatttttgag aggaaatcat gtagtacaaa gttgtaatgt taaagaacat
     1801 ccaacaggtc aatatattaa aagaaaaatt actaaataat gcggggggaa ataagaatga
     1861 tggatatact tattaagaat gccataatag taactgtgaa taaagagaga gaagttattt
     1921 ttgatggggc attagtagta aaagataaca agattgctga tattggaaat tctaaagaga
     1981 tagaaagtaa atatactgat gttaaaaaaa ttatagatgc taaaggtaaa gttttattcc
     2041 caggttttat aaatacacat aatcatttat tccaaacttt attaaaagga ttgggagatg
     2101 atatggtact taaagactgg ttagaaacta tgacatttcc agcagctaac tatttagagc
     2161 caaaagatac ttatgatgct gcaatgcttg gatgtattga aggacttaga agtggtataa
     2221 cgaccatggt tgactacatg tatcctcata gtaagccagg tctttgtgat ggaataatag
     2281 atgcttataa agaattagga ataagaggaa tacttggaag aggatgtatg aatacaggag
     2341 ctcaatttgg agttcatcct ggaataatgc aagatgtaga aacggttgaa aaagatgtaa
     2401 gaagattgtt tgaaaaacac cataatacag aaaatggaag aatcaaaata ggagtagctc
     2461 ctgcagcaat atggtcaaat tctcaagaaa tgcttgaaat gctatggaga gtggtaaaag
     2521 aatatgatga tgctttattt acagtacata tatcagagac tccttttgat agagaagcag
     2581 caaaagaatt gcatgggcaa tatgacatag atgttttaga aaaattagga atacttggac
     2641 caaatgtgct tatggtacat tgtgtgtatc taactgaaaa agatatggaa cttactaaaa
     2701 aatacgatat gaaagtgtct cataatacag caagtaatat gtacttatct tcaggtgttg
     2761 caccagtgcc agaaatgctt aaaaaaggaa taacagttag tttaggagta gatggagccg
     2821 ctagtaataa ctctcaagat atgcttgaac ttatgaaatt aacagcactt caacataaag
     2881 ttaataagtg tgacccatta gcaatgtcgg cagaaaaagt tcttgagttg gcaactatag
     2941 atggagcaag agctattgga atggaagatg agataggttc attggagata ggtaaaaaag
     3001 cagacttact aatatttaat ccaatgcttt caccaaaagc gatacctatg cataatccgg
     3061 tatctacatt agtatattct tctagtatga aaaatataga gagtgttata gtagatggaa
     3121 atataataat ggaagattca aaaatattga cagctaatga agagaaagca ttaaaagatg
     3181 ctcaagatac agctgagaga ctttgtgtaa gaggaactat aaaaaataga atggaaggtc
     3241 ataaatggaa tagcctttat taataaatgt aatttattca tagaaaagta tagtaaaact
     3301 ttagcttaaa aatatgagtt ttgaggtgat ttatttgatt atcaaatgta ccataaataa
     3361 taaagaaaaa gaattaagta taagaccaga tgatttttta gcagatacat taagagaaaa
     3421 tggatatgta agtgttaaaa aagggtgtga tacaggctca tgtgggttat gtacagtgat
     3481 ggtaaatgac aaggccgtgc tttcatgtaa ttatcttact gctagagtag atggtcagca
     3541 tattacaaca cttgaggggg tcttggatga agcaaagaag tttggagatt ttcttgcaga
     3601 cgaaggggct gaccagtgtg gattttgtgc tcctggattt ataatgatgg ttttggcaat
     3661 gaaaagagag cttcaaaatc caacagaaga agaagttata gattatgtaa atggtaacct
     3721 ttgtagatgt acaggatata aaggtcaatt aagagcaata cataaatatt taaacactta
     3781 gacttttaag tgaaaattaa gttgatatgg ggagagagta tgataactat aaaggaatat
     3841 gtagttccaa aaagtttaga tgaagcttat gaactgctaa tatcaagaaa aaacaacata
     3901 atacttggag gatgtggatt tttaaaacta ggtagtaaaa atattggctc agcaatagat
     3961 ttaaaagact tagctttaga ttatataaat gaaactgatg atagcatatt aattggagca
     4021 gacacaagtt taagaacttt agaattaaat aaggttatta aaaattactg taatggggta
     4081 atttcaaacg ctgtttctaa tatagtagga gttcaattta gaagtggagc cagagtagga
     4141 gctagcgtat ttgctaagta tggattttca gatttaatac cttcattact agtggtagat
     4201 gcaaaggtta agttatataa aaaaggggtt atgaacttag ctgatttttt agaaagtgag
     4261 cttgaaaaag atatattaat agaagttata ttacctaaaa aagatgctat aggtgtattt
     4321 gattctataa gaaaatgtac aggtgatttt gcagtattaa atggagcaat gttaaaagaa
     4381 ggaagtattt ataaaattgc gataggcgct agaccaagaa gagcaaaaat tgcctataaa
     4441 gcaagtgaaa tattaagttt agaaaatgat atagaaaaag ctggtgaagt atcaagtgaa
     4501 gaactttcat ttggaagtaa tataagagga agtaaagaat acagaaaaga tatggcaaaa
     4561 gccttagtag tgagaatgta taatagtatt ggaggtgagt gtgatggtaa ataaagaggt
     4621 aagaaaaata gatagtgaag ccattgttac tggaaaacca atatatacag aagatttaat
     4681 ttttcataaa gatgttttaa caattaagct tcttagaagt ccgcatgctt ttgcgaagat
     4741 aaaaaacata gatacaaaaa atgcattaaa ggtaaaaggt gtagtaaaca tattcactta
     4801 caaagatgtt ccaaattata gatattcaat ggttggagag tcatatccag aagcatcacc
     4861 tcatgaccaa ttaatacttg aagacgtagt tagatatgta ggagatgaag ttgctataat
     4921 agccgctgaa gatgaaaggg ctgctattaa agctatgaaa cttataaaag ttgaatatga
     4981 agtaatgact cctatattgg atgcaagaga atcggaagga aataaaattt taatccatga
     5041 agaagatgat ttgttttgtc catttgattt tggattggat gctacaaaaa atattgtatc
     5101 gagagaaaaa atgggtaaag gggatgtaga aaaagagttt aaagaaagtg atgtaatagt
     5161 agaacattct tatatgactc aatcacaagc ccattgtatg atggaaactc atagagctta
     5221 tacgtatata gatacgaatg gcagattagt agtaacttct gcaaaccaat cagcttatca
     5281 tatgagaaga caggtttcta aagcactggg aatacctctt tcaaaagtta gagtaataaa
     5341 accaagaata ggtggaggtt ttggtggaaa aaacatagct gtaacagaga tatatgcatc
     5401 atttgtaact tggatgacaa aaagaccagc aaaactaatt tatactagag aagaaacttt
     5461 tgcaatgact aatactagac atcagatgtt ttttgatata aaaattgggg cagataaaga
     5521 aggaaacata aaagctatag atatgaaagc attgaataat acaggcgctt atggtgataa
     5581 tggaccttca gtttgctctg aatcaggtca taatgtactt ccaacatata ataatgtacc
     5641 tgcaataaaa tttgatggga gaactgtata tactaattta gttccaggag gagcattaag
     5701 aggatatgga gcaacacaag gtacatttgc acttgattgt gcaattgatg aattagcgca
     5761 taaacttaat atggacccaa cagaaataaa gttaaagaat attataaaaa aacaaactga
     5821 aggcggaata atgaattttc caataagaag ttgtgcactt gatgaatgta taattagagg
     5881 taaaaaactt attggatggg atgaaaagta ccctgttagg gatattggaa acaataaggt
     5941 gagggctgtt ggaatgtctg tgggaactca tggttctggt atagccaaca tagacatggc
     6001 aatagtaaat atgaggatgg atgaagatgg aacttataag ttgttttctg ggtcttcaga
     6061 cttaggaact ggttctgaca caatacttgc acaaatagct gcaaaagcat tgaatacatc
     6121 tattgataga atttccgttt atacaggaga tacagatatg tgtccatatg atactggtgc
     6181 atacgcttct tgtactactt atgtaactgg aaatgctaca ataaaatctg ctgaaagttt
     6241 aaaacaaaag atattaaaag tagcacagaa gaaactcgat ttaccaatag atgatttaat
     6301 actatatgaa gacagagttt gttatagtga agatgtagag aagtttgttt tgttaagtga
     6361 attaggaaaa gaatctgttg gtggtggaaa tcaagaagtt ttatattcat ctgaatctta
     6421 tggtatacaa gagagtgcta aaccattctt agcaggattt gctgaaatag agttagataa
     6481 aacaacaggg gagtttaaag taataaatta tgcttgttct acagattgtg gtacagttat
     6541 gaatcctgca cttgctagaa tacaagttga aggtggtgta actcaaggta tagggcttgc
     6601 aatgtatgaa gaccctagac atggttctga tggaaagctt caaacttcta atctattaca
     6661 atacaaagtt ccaacaaaaa aagatatagg aaacataatt gttgattttg tagataatta
     6721 tgagccaaca ggtccatatg gagctaaatc tttaggagaa atagttattc atacacctgc
     6781 accagcaata gcaaatgcaa tatacaatgc cacaggagtt cgtataagag aacttcctat
     6841 aacttctgag aaagtttata tggccatgaa aaaattaaat cagggaggta aataaatgat
     6901 tgctattaaa agtaaatact taatatcttc tgctgatgaa atatatacaa attctgctgc
     6961 tgtagtagaa aatgacatta taaaagatat attgccaaat gaagaagttg aaataaaata
     7021 taaaaatatt gaagaaataa tagataaatc agatgctata ataatgccag gattcgtcaa
     7081 tggtcatatg catcaatatg gagttctttc taggggaata ccggcaaatg tacattttac
     7141 tgactttgaa ggttttttaa atgactattg gtggccattt atagaaaata gaattggatt
     7201 gaaagaagtg aaggcaacaa ctaaagcatc agcaatagaa cttatagaat ctggtgtggt
     7261 agctttttgt gataccctag aagctccaaa tacagaagaa ggaactttaa ttgagcaagg
     7321 aaaaatacta gaagaaatag gcatgaaagc gattttatcc ttagaaagtt gtgaaagaat
     7381 aagctttgaa aatggactta gatgtttaga tgaaaattct aatttaataa agtggagtag
     7441 agaaaatagt aaattaataa atggaataat gtgtacacat acaagcttca catgttctga
     7501 tagatttatt aagaaagcta aagaagatgc aaaaaaatta aatgcaccaa tgcaatttca
     7561 tttatgtgag agtatatatg agccaaacta tgctgaaaaa cattttggca aaaaagcagt
     7621 tgactactat aatgatttag atatattgga tgaaactgta ttagcatctc agtgtgtaaa
     7681 agtaaatgat gaagaaatag atatattaaa agaaaaaggt gtaaaagtgg ttcatatgcc
     7741 tcttagcaac tgtgaagtag gtggaggttt ttctccagta ccaaaaatga ttaaaaaagg
     7801 cataaaagtg gcactgggta ctgatggata tataaatgat ttttttgaag ttatgagagg
     7861 tgcattttta atgcataaat cagttgaaga agatgcatca gtaatgccag caaatttagt
     7921 atttaggatg gcaacagagc atggtgctta tgtattagga cttcaaaatt ctggtaaaat
     7981 agcagttggt aataaggctg atataatagt tatggaagat gaatttaaaa ctcctgtgac
     8041 tcttgataat atatttgacc agatagtagt tcagggtaaa aaagaattta tatcaaatgt
     8101 atacatagat ggtagacata ttttaaaaga aaaacagtta gttgatttag ataaaaaagc
     8161 tattgttaaa gaaatgaaag aagttgcttg tgaattttgg aaattttaac gaatgtaaat
     8221 atatatgaaa aggggaagca gataatgtat aattttttag gtaaagaatt aaaatcacca
     8281 cttataatag gttcaggacc attaacatat agtgcagctg gatgcaagat attaagtgat
     8341 gcaggagcag gggcagttgt gactaagact ataagaaaag aaagagctat aaatccagca
     8401 ccacatatgg ttagaaatac agctaatgct cttttaaata atgaaaaatg gacagatttt
     8461 gagccagagc aatggataga ttttgaaata ccacaaatga aaagagatgg gactgtctgt
     8521 atagcttcag taggtcatac aattgaagaa agtagcgaat tagtagagaa agttgcaaat
     8581 gcaggagctg actttattga attagtatct tatgactata gagatttgat accaatgctt
     8641 aaagatgcaa aggaaagagt aaatatacct gtaatagtta aacttcctcc tatgatagat
     8701 gagataggcg attttgctaa aaaattagaa gaagcaggag cagatgcaat aactgcttgt
     8761 gactctgtag gaccagcatt tagaatagac atagaaacag ggcaaccttt attaggtgga
     8821 aatggaatag gatatttaag tggagaaact attaagccaa taactttaca gagaatatat
     8881 gaaataaaaa aacaagttaa tataccaata attggcttag gtggatgtgt aagtggagat
     8941 gatgccttag aaatgattat ggcaggtgct gactttgttg gtatatgttc agtagtaatt
     9001 ttaaaaggcg cacaagtaat atctaaaata catgatgatt taaaatctaa tcttaataga
     9061 ttaggatata atactataga aaatgcttgt ggtatagtac ataatcatat gggagatgtt
     9121 aatgaaagac ttagctttga gtttacttat gatgaagaaa aatgtactaa atgtaagatg
     9181 tgcgagagag tttgtgcata tcaagcgaga aaattgaatg ataagatgga attgaatgaa
     9241 gaagagtgta gatattgtgg actttgtata tcagtttgta aaccaaaagc acttggaaga
     9301 aaaatttcat gttcagagct gaatgtatag attattttat aaaaaacaaa gttttaaata
     9361 aaaataagaa aggctatctc aaagagataa gccttttttg ttgttgacct tatttttgtt
     9421 tatttgtagt tattttagat attaattagt tttgaagtaa taaagtgaat caattttgtt
     9481 taattaaaat tttaataatt ctgatatata tgttaacatt gtatagcatt tgtgtaaaat
     9541 gttataataa ttaataggga tggtgatgca agtgcaagag aagattttag agttattata
     9601 tactataaat gaagatgtag ttagcataaa aaatgatatg tcggaagtaa a
//
LOCUS       DAEQJM010000101         9621 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.103, whole genome shotgun sequence.
ACCESSION   DAEQJM010000101 DAEQJM010000000
VERSION     DAEQJM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9621
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.103"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            110..1750
                     /locus_tag="KRQ43_003365"
     CDS             110..1750
                     /locus_tag="KRQ43_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH2743702.1"
                     /translation="MFDVKIANGIIIDGTGNSRYKGDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPIKLNLHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDKVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWDGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            2109..3431
                     /locus_tag="KRQ43_003366"
     CDS             2109..3431
                     /locus_tag="KRQ43_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743703.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIDTYDKAMLKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDICCC
                     ITGLEEAYHAMKKENIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIVVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPAVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAI
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            3628..4635
                     /locus_tag="KRQ43_003367"
     CDS             3628..4635
                     /locus_tag="KRQ43_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH2743704.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDK
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGTMGCPPEILKKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            4673..6070
                     /locus_tag="KRQ43_003368"
     CDS             4673..6070
                     /locus_tag="KRQ43_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HBH2743705.1"
                     /translation="MASTNKNNVTSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKGNIDKINTNKSDINKVNIDTVDTDKLNTNTLTEKNKKVIFKGEDN
                     MSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDYIMKITHNIWE
                     EKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIGQNVIWSNFGA
                     DGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEWLVRDNLWIVT
                     QLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDDSVGEMMLEMT
                     SRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIPNGSYEVERVT
                     CNQREKNEGYDVSIRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQGKVKEEWITF
                     DGMDVLKQMYMGVEE"
     gene            6215..7480
                     /locus_tag="KRQ43_003369"
     CDS             6215..7480
                     /locus_tag="KRQ43_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH2743706.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTDIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            7522..8561
                     /locus_tag="KRQ43_003370"
                     /pseudo
     CDS             7522..8561
                     /locus_tag="KRQ43_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
     gene            8596..9618
                     /locus_tag="KRQ43_003371"
     CDS             8596..9618
                     /locus_tag="KRQ43_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH2743707.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMVAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
BASE COUNT         3516 a         1075 c         1938 g         3092 t
ORIGIN      
        1 aataggattg tttactagga ggaaagacta gaattatttg ttgagaaaaa agaataggat
       61 tgtttattaa gaaatatgaa tataaataag tcttgaaagg agaagaagaa tgtttgatgt
      121 taaaattgcc aatggaataa tcattgatgg tacaggaaat tcaagatata aaggtgatgt
      181 agggattgta ggagacaaaa tcatggctat tggagatcta agtcaaaaag aggctaaaga
      241 gactatagac gcaactggaa aatttgtatc acctggtttt atagatttcc acactcattc
      301 tgatttatct cttgtgtatg acaaatacac aagaagccgt atccatacag gtgtaacaac
      361 agacgttatt gcaaactgtg gtataggagt tgctccgata agagaagaga agaagcagga
      421 gttaattgac tatcttggaa cgaggataat tggtacaatt ccaataaaat tgaaccttca
      481 ctggaataca atgcaggaat actttgatta cttaactgaa aattctccag cagtaaatgt
      541 tgtagcttat gtagcacaag gacctgtacg tatcaatgaa atgggatttt caaaggagcc
      601 agctacttta gagcaactta aaaatatgaa gttggaagtt agaaaggcta tggaagctgg
      661 atgtgtagct ctttcgtcag gattagttta tttaccagga gcatatacaa agaaagaaga
      721 aatggctgaa ttatgtaagg aattgatacc atacaatgga tactatatat ctcatattag
      781 agatgagggt gatgaagaaa tggaagctct tgatgaagca atttatatag ctaagacggc
      841 aggagttcct ctacatattt ctcatttaaa agtcatgggt cataagaatt ttggaactat
      901 tgataaggta tttaaaaagc tagatgaagc tgaggcagat ggcttggaag ttacttttga
      961 ttgttaccca tatacagctg gaatgacatc tttgggtgca cttttacctc cttgggcttt
     1021 tgaaggtggt gtagaaaaca tggtaaaacg attagaagtg caagaaaata gggacagaat
     1081 tataaaagag ctagaggaag ggattcctgg atggcaatgt ttctaccagt tagcaggtgg
     1141 ttgggacggt gttgtactag cctctgtaat gactgaagca aataaatatg tagagggtaa
     1201 aactttaatg gaggtagcta aaatcaatgg tgaaaatcca tttgatacgt tctttaggct
     1261 tttgattgaa gaaaaaagta aaattcaagt agttgttcat acacaaggtc aagaggatac
     1321 agataaggtc gtttgccatc caaagtcatg tataggttct gatagtatgg acctttctac
     1381 agaaggctta ctttctcttg gaaagcctca tccccgtgca tttggtactt ttggacgaat
     1441 tttctcttac tatgttagag aaaaaggtat gttgactttt gaggaagcag ttaaaaagat
     1501 aacttatctt tcagcaaaac gcttaggaat ttataaagaa aggggtctac ttaaggaaaa
     1561 ttattttgct gacattgtgg tatttgaccc agatacaata gaagataaag cgacttatag
     1621 taatcctaaa cagtatacag tgggagtgga atatgtattg gtaaatggta aaattgcatt
     1681 ggcaggagga aagcaaactg atgtatgtgc tggacgtgta attaaaaatc ctcttagcat
     1741 agcaaaatag aatacattaa gaacttttat aaaaatagtc tttctttgaa tattaaggaa
     1801 ggctattttt gttaaattaa taaagattac tctacttgtg ttttctagag aatttaactt
     1861 taagtagaaa aaacaatata ttaattgtaa aatgtaatta atattaatgg ataagattta
     1921 aatacaaaaa cttaaataca aaaatgtttt aacagatagt cataattaaa aaacttaaag
     1981 taacttttta tataagatat aattgattat gcaaaatttt atgaagcagc aaccttgtta
     2041 ctttaagtca agggaggttc agaaagtgtc ttaagagata atagtatctt taggaaagga
     2101 gaaacgaaat gaaaatactt tatgtaggac caggcatggt aatcgacaaa atactagcag
     2161 taagtaaaaa gaattttccc aatattgaag cagattttct tagatatgat agatatattg
     2221 aagtacctga tttattggaa aaatatagag gtagagtaga tgcagttctt tttacaggta
     2281 aatcgccatt taaatttttt gaaaaaagac aaaaagattt tgtgttgtct gattatattc
     2341 ctagacatga aacaacatta tacagagtat tgcttgaaat tacatatttg cttaaattcg
     2401 atattagtag acttagtata gatacttatg ataaagctat gctgaagaga ttgtataaag
     2461 aaattggagt tgaatttaag gatgaacata tgttttttgc agagcaaaag tatttagaag
     2521 aggactacat aaagtttgtg cttgaatttc ataaatataa ttatcaaaat aatgacatat
     2581 gttgttgtat tacaggtctt gaagaagcat atcatgcaat gaaaaaagag aatattccag
     2641 tagttttagc cttgccttct gaggatgtaa tggtacaaag tataaaaaac attcagatgc
     2701 gttatattgc aaagaaaaac aatgagaatc agattgttgt tcttgctatc aaacttaata
     2761 tgccttcaga atattcactg atgaaggaag atgagtacgc ttatctttca caaaggatta
     2821 agattcttga taaactatac catttcaata gccgtataga tggtgttttg gtagagcaga
     2881 gtagaagcga atttatgatt tttacaacta aaaaaatact tgagttagaa acaaagaagt
     2941 acagagatat ttatttgttg gatatgattc gtgaagtttc agttataaac acttatatag
     3001 gaattggtta tggaaaaaca gcaaatgaag ctaaatttaa cgcttatgag agtattaaga
     3061 tggctcaaag tcaaaaaaat gatgcagcat atgtagtttt tgaaaatgga gaaattatgg
     3121 gaccactaaa gccaaatcct gctgtcaaag agaaaaatag ctttgatgaa cgattttatc
     3181 aaattgctac agagacaggg ctaagtgcta atactgtata taaagtgttc aataaaataa
     3241 taaatagtgg aaaaactgaa tttacatcaa aggaattagc tattatatgt ggtgtaagta
     3301 ttagaactat ggacaggatt atacttagat tgtgtgattc tggttattgt gaggtagtga
     3361 gtgaacagct tatgagcaag tatggtagac ccagtagaat attacgtttt aaaccttttc
     3421 tgttgtttta aatagatata agttaaaaat taaattttta tgataacatt ttctttacaa
     3481 ttttttagat atatgttaat atttagaaaa atgcatatgt attcataaaa taaactcaaa
     3541 atagctaaaa aatcattaaa aaggaaatcg tatgcataaa atgagaaagt taatttataa
     3601 cttaaataaa tctgggagga gataattatg ggaaaatatc aggattcaaa aaaagttgta
     3661 agaaattatt ttgaagcatt agaaaatgct actggggatg aggttgaaaa tgtcttaaag
     3721 caacatatga aatcagatta taactggaaa ggtgtgtatc catttcgtga acaagaaggc
     3781 actgaaaatg tagcagatgt attttggaag cctttaaaaa aatcattgag taatatgcaa
     3841 agacgacaag atattttcat tgcaggaaca aatgagattg acaatagtga atgggtaatg
     3901 agtatggggc attttatggg actttttgat aaggattggc ttggcattaa acatactcgt
     3961 aaaatgatta gtttaagata tgcagaattt aactgtgttc aagatggtaa aattgctaaa
     4021 actggattat ttgtagatat aattgggttt atgattcaag caggagttaa tccattgcca
     4081 ccacaaacag gttcatattt tgtatatcca gggccaattg accataatgg attacttttt
     4141 gaagatgcag atgaagttga aggagtaaaa actttagcat tagtaaataa aatggtagat
     4201 gatttatctg aattaaatga aagtggtact atgggatgcc caccagaaat acttaaaaaa
     4261 tcttgggcta aagatatgat ttggtatggt ccaggtggaa ttggtgcttc ttatactata
     4321 cctagatatc aagagcaaca ccagctacca tttagaaata atttaaaagg aaagactttc
     4381 aatgggcatg tatgtagatt tgcagaaggt aattttgctt gtttctttgg atggcctaat
     4441 ctgactaatg taccatgtgg aggtttttta ggattaccag gtggagaggt taaagcagat
     4501 atgcaagttg ttgatgttta ttatcgtaag ggcgataaac ttcaagaaaa ctgggtgtta
     4561 attgatattc cttattggtt gaaacaacaa gggcttgata ttcttgagag aactaaaagt
     4621 atttttaatg cttagttatg catacgtatt ctaaaacaaa gggggatata aagtggcatc
     4681 taccaacaaa aataatgtaa caagtaaaga ggaagaaaaa gaagtttcta caagtgggct
     4741 tgaatcatgt acggttaaag aaaacaaagc taaaatgaat caaactaatt ttagtaatat
     4801 aaatgaaaat caaacaaatg agaataaaac gaacacatat aaaggaaata tagataaaat
     4861 aaacacaaat aaatccgaca taaataaagt taacatagat acagtggata cagataaatt
     4921 aaatacaaat actcttactg aaaaaaataa aaaagttata tttaaggggg aagataatat
     4981 gtcatctaca aaaatttact atggagattc attagaagta acgcctgttg gagtaatgga
     5041 ttacaatgat ttttcaaaac agacaaaaag ggaacaggaa atacctggat ttgattctaa
     5101 gtatagagat tttgtagatt atattatgaa gattacacat aatatctggg aagaaaaagg
     5161 tataggtgtt atttatgata catatcacaa taatgttaca atgcattgtg gctcttcaaa
     5221 tttagttggt attaaagatg ttatttccaa tactcttcaa acattacatg cgtttcctga
     5281 tagaagatta attggtcaaa atgtaatatg gtctaacttt ggtgctgatg gttttttatc
     5341 ttctcaccgt gttttgtcta cagcaactaa cttaggtgat agtaattttg gaccagcaac
     5401 aggtagaaaa ataaacttta gaactgtaat tgattgtgcc acaactaaca atagaatcca
     5461 cgaagaatgg ttggttagag ataatttatg gattgttact caattaggat taaaccctca
     5521 ggaagtagca aagagtatgg caaaggcaag tgaatctaaa gtgcttagct tacaatcaac
     5581 ttatggtatc tgtgaatcta tggatggtca atttatgcca actaagtatc aagcaaaaga
     5641 tgattctgtt ggcgaaatga tgcttgaaat gacaagccgt atttataatt ataaatatat
     5701 aaatgaagtt aaaaaatact atcatgataa tgcagtagta cattttatat gtgataaaga
     5761 tttaaatggt tatgatgaga ttcaaggaat gattgtaagt ttacttgcat caattccaaa
     5821 tggaagttat gaagtggaaa gagtaacttg taatcaaaga gaaaaaaatg aaggttatga
     5881 tgtatctata agatggagat tacgtggaat aaatgaaggt ataggatttt ttggacagcc
     5941 ttctggaaag catatagaag taatgggaat caatcattat catatacttc aaggtaaagt
     6001 aaaggaagag tggataactt ttgatggtat ggatgtatta aaacaaatgt atatgggagt
     6061 agaagaataa agctgtttag agtataaata attttgaaat gtatataggg aagtattgct
     6121 ttataaaatt taagtgggga atgtatatga aaaatagatg tttaaacttt tagcaaaaat
     6181 tatgactaaa tttaaaaggg ggaattataa aaatatgaaa acaacggttg aaatagaaaa
     6241 tgatatcata ttaggaaaag actattcaaa cctaaaaaga ggaattgcat ttttttcaat
     6301 tgctttaata tacttttttt attgctacaa ttttatggtg ggtactttta ttaaaccaac
     6361 aatgatttat gctttagcag atgggggatt tggcttttca ttaaaacaaa cagaagaaat
     6421 atttgcagtt atgtcttttg gtacaattcc aggtacattt atttttgggg tgatttctac
     6481 aaaaattggg aagaagagga ctttaattag cgttgcttta ctgattggat tgacaacatt
     6541 tataccaatg ttatctccta cagatattat gttatggaaa atagcacgtt tgtgtacagg
     6601 agtagtgttg ggaggcgtat ttggaacagc tatgccttta gttgcagata tgtttccaag
     6661 taaatatcgt ggtaagttag ctgctatatt aactgcttta ttttcattag caatgatttt
     6721 tggtgggaaa gtatatggcg ttttaggtga tgcaaattgg caaatattga tgtatactgc
     6781 gattatacca cctatagttg gagctatctt agcaatcttc tttgtgccag atgatttgga
     6841 gtatacaaag gaattagtta aaaagggaaa agaaactggt gaaaagatta gctatataag
     6901 tatgtataag ggaaaatact tatggattgg attgggaacg attcttttat caggtgcaaa
     6961 ttttacagca tattcagcat tttcaaataa tgcaactaca tacctagtga caggaatagg
     7021 aatgtcagca gcagtggctg ggtctatata tagtttacaa ggaattggtc aattagtagg
     7081 atatttattc tggggttcaa ttgcagataa atttggaaga aaaatacctt ttataggtat
     7141 ggcattagca gcagtatttg tttttatata tacaaaatta ggtggagata atacaacaac
     7201 attctatatg atatcagtat tactaggtgt tgctgttgga tattctggag catggggagc
     7261 atactacaca gagttgtttc caagtaaata tcgttcgttg tcatctggta tgtcatttaa
     7321 tggaggaagg attatatcta cgtttgcaat acctgctata gctggtacag cttctggtac
     7381 tttaggtatg atgactatct tttacatatc aatcgcagtc tttgtagcag gtgctattgt
     7441 atggttattc ttaccagaga cgttaaataa taaaaaataa aatactagga atttattttg
     7501 ttacttagaa aggggtggct tatgatttca tcaattgatg tatgtattat aataggatat
     7561 ttgctattaa tgttagttat tggttattat tcaggaaaag ataataaaaa tcaagaagat
     7621 tatttcttgg caggtaggtc aatgccatgg attccaattg ctttatcagt tgcagctact
     7681 atgattagtg caaatggctt tataggtggt cctggatggg catatgtaga tggaatgtat
     7741 ccagtaatgt aaaatgtgca aaaaattctt ttgtagttag tgcatttgtt atgaatttag
     7801 tttactactt tatgctattg gtaggagtaa ttttatttgt tttttatggg ggaaggacat
     7861 ttgaaacttc aaatgaaata atgattactt ttattttaaa tgaacttcca gtaggagcca
     7921 ttggaattat tattgcaggt gtgtttgcag cagcaatgtc tagtatcgac tctatattaa
     7981 acagtatgac aactgttttt acgaaggata tttatgagtt ttatttcaaa aaagacaaca
     8041 aagaatcatc attaaaagtt acaatgatta taactgtagt tataggagtt gttatgacag
     8101 gttttattat tatgggattt ggaggaagca tcaaatcaat tcttgacctt gttggtaact
     8161 atatctcata ctttgctgga ccagctacag gtgcatttgt actagcaatg tttacatata
     8221 aagctaatga taaaggagta tctattggtt ttattgtagg gttagtttta ggatttttta
     8281 tttctaataa atataatgtg agttggttgt ggaatccagc aataggtgct acaataacat
     8341 tgatatttgg atatattttt agtgtcattt taaagaaaaa tcataaagta gatgatatta
     8401 aaaaatacac tgcatttggt atgagaaatc accttatttc tcaaggaatg gataaagtag
     8461 atggagtatc tatagtgcca ttttctttag gtaaacaaga actaattgta ttagcttttt
     8521 ttattatcca atatattata ttatttttga tacaatttta agaagaaata ctagatattt
     8581 aaggagaaat actaaatgaa tcaaaagaaa gttcattata ataaatcggc tacatcaaaa
     8641 gatgtcgcaa gattggcagg agtatctcaa tcatctgttt caagagcatt tggtagtgca
     8701 aatggaaagg gcgtaaaacc tgaagtaaga gaaagaattt ttcgtgtagc aaacgaaata
     8761 gggtatgttc ctaatttggt agcacgggga atgattagtg gaaaaactaa tgttataggt
     8821 ttgatagttg gtgatagtct aggtccattt tacaatagaa ttatcaattt atttgtagaa
     8881 aaaattcaag agataggtaa acagtgtctc gtttttaaag ttcctagaca acaaagtata
     8941 gatagtataa tttcaaaagt aattcagttt caagtagaag ctgtgattat tacagcttcg
     9001 gccatgaata aggtgatggc tgagacttgt gaagaaaaca atattcctgt gattcttttt
     9061 aatcgtttta tacctggtat aaaaataagt acagtctatg tagacccaat tgaaggtggg
     9121 ggcatggttg ctgaatatct gcttaagaaa ggtcataaga atataggata tattcaattt
     9181 acgagagaaa caagtgaaga aatggaaaag aaaattggat tttattctaa gttaagacaa
     9241 agtgggattc ataaccttaa agaagaatct gcaaactatg attatgattc tggatatgaa
     9301 gcaggtaaga gaatgttagc attatcaaat cctccaacag caattttttg cacaagtgac
     9361 ttgatagcta ttggtgtaat ggatgctgca aggtttgagt acaagttgag ggtgccagag
     9421 gatttatcag tgataggata tgatgatatt caaatggctt catggaagag ttataattta
     9481 acgacgatta gacaaccact agatttgttg attgaaaaaa caattaacat acttaagtcc
     9541 ttattaaatg aagaaaatcc agagtcagtc gttgaaatgt taaaacctga attgattgaa
     9601 agaggttcta cactttaagt g
//
LOCUS       DAEQJM010000102         9529 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.104, whole genome shotgun sequence.
ACCESSION   DAEQJM010000102 DAEQJM010000000
VERSION     DAEQJM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9529
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.104"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..146
                     /locus_tag="KRQ43_003372"
     CDS             <1..146
                     /locus_tag="KRQ43_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH2743708.1"
                     /translation="TDGKLKLAKKAKELGLDAIHDTVHEMCKDEARHGKAFLGLLNRY
                     FGK"
     gene            420..680
                     /locus_tag="KRQ43_003373"
     CDS             420..680
                     /locus_tag="KRQ43_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743709.1"
                     /translation="MFKTVFEDKEYVLLCKNYSKSDGVKAIFIYLISMLLLFFQGYLY
                     TTNLSSTILTNSQMILSILILLIGLGFVLLSKEKLNTIGITM"
     gene            699..1127
                     /locus_tag="KRQ43_003374"
     CDS             699..1127
                     /locus_tag="KRQ43_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH2743710.1"
                     /translation="MYGVIGATVLVIFVILTAGIMQGKKVDFQLPTVFMIVTFIVSAI
                     SEEIVFRGYIQTRLTGLIKNSVLSSCINAFLFLSTHYPVKWISSGDFSFAILSGFYVI
                     CLILLNFSCDLVYRKTNCLWGAWLLHILYNIGTGVLIFTT"
     gene            1247..1855
                     /locus_tag="KRQ43_003375"
     CDS             1247..1855
                     /locus_tag="KRQ43_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBH2743711.1"
                     /translation="MVDNLIKYIHKSNIAIVVLHEIYGVNNFIKDVCQKYYKGGYDVF
                     CPELLGEKRVFSYLKAQEAYDFFINNVKFDIYKKVEKLINGLKSEYKHVFVVGYSIGA
                     TIAWRCSENSLCDGIICCYGSRIRDYMDVIPTCPILLVFAKYDSFDVDYVSSQLSRRQ
                     NIQIEILDANHGFIDTYSKNYSNAQTEVFNIKEKNFLSKCLG"
     gene            2379..2591
                     /locus_tag="KRQ43_003376"
     CDS             2379..2591
                     /locus_tag="KRQ43_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH2743712.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            2604..2825
                     /locus_tag="KRQ43_003377"
     CDS             2604..2825
                     /locus_tag="KRQ43_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH2743713.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            2925..5081
                     /gene="feoB"
                     /locus_tag="KRQ43_003378"
     CDS             2925..5081
                     /gene="feoB"
                     /locus_tag="KRQ43_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH2743714.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTIIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHVPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            5107..5259
                     /locus_tag="KRQ43_003379"
     CDS             5107..5259
                     /locus_tag="KRQ43_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBH2743715.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            5439..6149
                     /locus_tag="KRQ43_003380"
     CDS             5439..6149
                     /locus_tag="KRQ43_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH2743716.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            6234..7004
                     /locus_tag="KRQ43_003381"
     CDS             6234..7004
                     /locus_tag="KRQ43_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743717.1"
                     /translation="MFEKIHKRFKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVVFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            6997..7728
                     /locus_tag="KRQ43_003382"
     CDS             6997..7728
                     /locus_tag="KRQ43_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743718.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            7762..8721
                     /locus_tag="KRQ43_003383"
     CDS             7762..8721
                     /locus_tag="KRQ43_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH2743719.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(8819..9415)
                     /locus_tag="KRQ43_003384"
     CDS             complement(8819..9415)
                     /locus_tag="KRQ43_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HBH2743720.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVNKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
BASE COUNT         3571 a          989 c         1706 g         3263 t
ORIGIN      
        1 caactgatgg aaaattaaaa ttagctaaaa aagctaaaga attaggacta gatgctatac
       61 acgatacagt acatgaaatg tgtaaagatg aagctagaca tggtaaagca ttcttaggat
      121 tattaaatag atattttgga aaataaattt aatataagtt aagtagattt ttaggagtat
      181 atcatttatg atttttaaaa ttataatgat atgctccttt ttaatagttg tattttatat
      241 tttttatagc tataatcttg taaatattta aatcattata aatatagttt taatgaaatt
      301 aattttttag ttttattatc tctgatttat gtaataaata gaattaattt gatttaaaca
      361 tatatttatg ataaaatatg agaaataaat aagaatttaa ttagaaagga gtatttatag
      421 tgtttaaaac tgtatttgaa gataaagaat atgttttatt atgtaagaat tattctaaaa
      481 gtgatggagt aaaagcaata tttatttatt tgatatctat gttactattg tttttccaag
      541 gttatttgta tacaacaaat ttaagttcaa caattttaac taactcacaa atgatattgt
      601 caatcttgat tttacttata gggctgggat ttgtactact ttcgaaggaa aaactaaata
      661 cgattgggat tacaatgtga aatttaaata aaagtctttt gtatggagtt attggtgcta
      721 ctgtactcgt aattttcgtt attttaacag ctggaattat gcaaggaaaa aaagttgatt
      781 ttcaattacc tactgttttt atgattgtta catttattgt ttctgctatt tcagaagaaa
      841 ttgtttttag agggtatatt caaacaaggt taactggatt aataaaaaat agtgtacttt
      901 catcttgtat taatgctttt ctttttctat ctacacatta ccctgtaaaa tggatttcaa
      961 gtggagattt ttcatttgca attctatctg gattttatgt gatatgcctt atattactta
     1021 acttttcatg tgatttagta tatcgaaaaa ctaactgtct gtggggggca tggctactgc
     1081 atatcttgta taacattggc acaggagtgc tgatttttac tacttagtca attttacttt
     1141 gcagaaagtt tatcgtaaga aacggattat tttataagtc aaattttaga gctagtaaat
     1201 tgacatactt aaaataattt aaactagatg taaaaaatat cgacaggtgg tggacaatct
     1261 gattaagtat atacataaaa gtaatatagc tattgttgta ctgcatgaaa tttatggagt
     1321 taataatttt ataaaagatg tttgtcaaaa gtattataaa ggtgggtatg atgtgttttg
     1381 tccagaactc ttaggagaaa aaagagtttt ttcatactta aaagctcaag aagcatatga
     1441 tttttttata aataatgtta agtttgatat ttataaaaaa gtagaaaaac ttataaatgg
     1501 tttaaaatcg gagtataaac atgtatttgt agttgggtat agtataggtg caactattgc
     1561 atggagatgt agtgaaaact ctttgtgtga tggtataatt tgttgttatg gctcccgaat
     1621 tagagattat atggatgtaa ttccaacatg tcctattttg ctagtgtttg caaaatacga
     1681 ttcattcgat gttgattatg tttcttctca actttctaga aggcaaaata ttcaaattga
     1741 aattttagac gcaaatcatg gttttattga tacatactca aaaaactatt ctaatgctca
     1801 aacagaagtt tttaatatta aagaaaaaaa ctttctatct aaatgtttag gctaatatgt
     1861 tttattataa aatatagaaa atttaatcaa tttgaaaaac ataatgacac tactaatgtt
     1921 aaaaaatatt agtagtgtca ttatattttt tgagatagag atagtcagta gaatcataga
     1981 attaattatg tttttatgat tgtattagat taatatttaa attacattga aaagaaaaaa
     2041 atcattacta tagaataata tctttatcaa aagaacattc ttatgcagaa tatggttatg
     2101 agtatctaag agaaatctca aaatatatag gatagcagta tgaattttta tagattttat
     2161 taatacaata aatcaaatga gaaaaaaaat caaaagaata caataatcac ttgcaaaaaa
     2221 tatgctattg tgatagactt aaatcaaaat taggaattgt aagaataagg aaaaagataa
     2281 gtaattattt taacgagtca aaatttaaga aattgtgatt tatatataag atagaggttg
     2341 tttgtaaatt taaattggtt gaagaggagg aatattatat gatgccattg atattatcaa
     2401 atacaggtga agaagtagtt ataaagaaaa tttcgggaag tgataagacg aggacttttt
     2461 taaatagtat aggttttgta gtaggtacaa atgttaaaat agtttctaag atagatggta
     2521 acttaataat agacgtaaaa gatactagag ttgcattaga taaaaaaatg gcaagtagaa
     2581 taataatata gggaggtaat gacatgaaca gactgaagga tattaagtgt ggagagactg
     2641 taaaagtcaa aaagttagaa ggagaaggag ctacacgaag acgtataatg gatatgggga
     2701 ttacaagagg tgttaatata tttataagaa aagtagctcc tcttggtgat ccaattgagg
     2761 taacagtcag agattatgaa ctatcaattc gtaagtcaga tgcagaaaaa attattgtgg
     2821 aataataaag attaattaga gtagggttaa tgtaattata taatgagaat gattttctgt
     2881 atcacaaaca gtgatgtatt taaataataa tggagggaat ggaaatgtca ataaaaatag
     2941 gtctcatagg aaatcctaac tgtggtaaga caacaatgtt caatgggctt acaggctcgt
     3001 cgcaatatgt tggtaactgg ccaggagtaa cagttgaaaa aaaaggtgga aaattaaaag
     3061 gaaataaaga tgtggaaata gtagatttac caggtattta ttctttatct ccatatacat
     3121 tagaagaagt agttacacgt aattttatgc tagatgataa gccggatgca gtaataaata
     3181 ttgtagacgc atcaaatata gagagaaatt tatatcttac aactcaagtt ttagagctag
     3241 gtataccgac cattatagct cttaatatga tggatattgt aaataagaat ggtgataaga
     3301 taaatattaa agaactatct gaagttatag gttgcccagt ggtagaagta acagcagtta
     3361 aaggtcaagg aattatggag gctgctgaaa aggcagttga acttgcaagt agtaacaata
     3421 aattaaattt caaattacct tttgttgatg aaagtaagga cgcaatagaa aaaattgaaa
     3481 aaataataga agaaaagact ccatatatag atgtagaaac acgctggtta gctataaagc
     3541 tatttgagag agatgaaaat gttatacaaa aacttgatat ttctaaaaca atattgaata
     3601 gtattgaaga aataactaga aattgtgaag atgaattgga tgatgatagt gaaagtataa
     3661 taacagccaa tcgttatgaa tttattagtt caataatttc aagtataata aagaagaatc
     3721 gaaaaggtaa ggaaactgta tcagataaga tagataagat tgtaacaaat cgtatactag
     3781 cattacctat ttttgcactt ataatgtggg gagtttacta tatagcagta agttcattgg
     3841 gtactatagc aactgattgg acaaatgatg tactgtttgg agaaattatt caaggcaatg
     3901 taagtaattt tctagcttct ttaaatgtag cagagtggtt acaaggactt gtagttgatg
     3961 gtctaattgg tggagttgga gcagtactag gatttgtacc acaaatcatg cttttattct
     4021 tattattgtc aatattagaa gattgtgggt atatgtcacg tgtagctttt ataatggata
     4081 gaattttccg taagtttggt ctttcaggaa aatcatttat accaatgctt ataagttcag
     4141 gttgtggagt tccaggagtt atgtcaactc gtactataga gaatgataga gatagaaaaa
     4201 tgactattat gttaactaca ttcattccat gtggagctaa gattccaata atagcattat
     4261 ttgcaggggc attatttgga ggtgcttcat gggtagctcc atcaatgtat ttcttaggta
     4321 ttgcaatgat aatcatttgt ggaattatat taaagaaaac tagtttattt gcaggagaac
     4381 catctccatt tgttatggaa ttacctcaat atcatgttcc aagtgcaaaa ggtgttttaa
     4441 tacatatgtg ggatagagga aaagcattta taatcaaagc aggaacaatt atatttgttg
     4501 cttgtggagt aatctggttc ttacaatcat ttaattggtc attacaaatg gtagatgctg
     4561 gagatagtat attagctagc ttaggaaata tagttgcacc aatatttgct cctcttggat
     4621 ttggaaattg gcaatcatca gtagcaacag ttacaggtct agtagctaag gaaaatgtag
     4681 ttggaacatt tggagtttta tttggtatat cagatgcaac agagcaagac ccaacacttc
     4741 ttgcttcagt tgcaagtatg tttacagtag ctagtgcgtt tgcatttatg gcatttaata
     4801 tgctttgtgc accttgtttt gcagctattg gagccataaa aagagaaatg ggttcatgga
     4861 aatggacatg gattacatta ggattccaaa ctttaacagc gtatataatt gctcttctta
     4921 taaatcaagt tggaagttta gttttaggta ctggaggaag tattgctggg gcaataatat
     4981 ctatatttat agcagtagca gtagtctttg tagttttaac ttattcaaat aaaaatatga
     5041 aaaaagaaaa aatgggtaaa ttaagttata tgaaaaatta attcatataa ataaggagtg
     5101 atgaatatgg ctacatttat tatagcagct attgtagtag tattaatggc actagctgta
     5161 atgtatatgg ttaaaaattc aaaaaagaat ggtagcagtt gtggatgtgg ttgttctgga
     5221 tgctcaagta gtaagagttg tcatagcgct aagagataaa taggataaga gcctgataaa
     5281 aagttaaatt gctttattat caggttctta ttttttatat aaataacaaa tttcatattt
     5341 gaagtaggtt agactatgct gtaattttac tgtataatta tatataaata tatgattagg
     5401 agggattatt gctaaattaa gcaatataag tgaatattat gtttaaattt gatgttacaa
     5461 acgagcttat gtgtatagca aggggaagtg gtaaattttt tgcaaaaaaa ggtgctatgg
     5521 tagcctttaa aggaaatttt aattttgaaa aattgctgtt aggtccaagt aatggcggtg
     5581 gattgggaag agcattatta ggtcatgttc agaggtcatt gacaggagaa caaatgccaa
     5641 taatggtggt tgaaggtgaa ggtgaaattt acctagctca aaatgcttac catgtagatg
     5701 taatatcaat tgacccaggt gattccattt atgttgagag tgaaaactta ttggcatttt
     5761 ctgaacaatt aaattacagt gtaaaattga ttggttcagg ggtaatatct caaaaaggtc
     5821 tttttactac acatttagta aataaaacag gtcaaaatca agatgttgct ataataacag
     5881 atggtaatcc tctaattctt gaaggacctt gttgtgttga cccagatgca ttagtagctt
     5941 ggactggaag agaaccatat cctaaagtat caaaactatc atggaagact tttattggtc
     6001 agacttcagg agaatcttat catatggaat ttgttgaacc tggacaaata gtcattatac
     6061 aaccatctga aagattgtct ggcttaaaaa cagattctac accttctgat agaatgagtt
     6121 caggtggatt aagacttggc atagattaaa tcttatgata tagcttaatt attatttaag
     6181 atattaaaaa ataaaaaggg tagcagggat agatatgtta aaaggagttt tatatgtttg
     6241 agaaaattca taaaaggttt aaaggatatt atattttttt aataatttta attttatgga
     6301 agatagtatg tgttttgggt atatggagta gctatattct gcctcctcct gaaatagtct
     6361 tagatacttt tataaaaatg atatatgacg gttctatttt cttaaatgtt tatgccagtg
     6421 taagaaggat attaataggt tttttaataa gttcattgat ggctatacca cttggagttg
     6481 tatttggagt aaataaaaaa atgtatgaat atttcaaacc actatttgaa tttatgcgaa
     6541 gtacacctcc actagctttg gtgccaatgc ttattttatg gtttggtata ggtgaagaat
     6601 ctaaaattat aattattatt ttggcatcct tttttccaat atttttaaat acattgaaag
     6661 gtataaaaaa ttgtgacaat aaattaatag aagtaggtaa atcttttaat ttatctaaaa
     6721 agagaatttt ttataaaata ataatcccta attctatgct ggatattgtt gttggactta
     6781 gtttagggct tgggtatagt tttagggcta taattggagc agagcttatt gcagcttctt
     6841 caggactagg atatttgatt tctgatggaa aagatatgtc tagaactgat gttgtattgg
     6901 taggaatttt tgttattgga tttttaggta tactttcaga ttatctattt tcaaagataa
     6961 taacaaaatt tagcaaaggg aagcaggttg atttaaatgg ttagaagtgg atttttgcta
     7021 gagaatatat ataagaaata tttagttgat aataaagagc atttagttct tgataatata
     7081 tctttaaata tatctagtga agagataact gttatattag gtgaaagtgg atgtgggaaa
     7141 acaacgctac ttagaatttt agcagggctt gaaaatgcta ctagtggaaa catatatttt
     7201 tttaataatg ataaaaagtg tactccaaaa gtaggaatgg tatttcaaga aagtagactt
     7261 atgccatggc tgaatgtaag tgaaaatata cttttacata ctgaaaaaga taatagaaat
     7321 aaagttgatt tagacaagta tttaaaaatg atgaagcttg aaaagtttaa aaactcatat
     7381 ccaaatgaat tatcaggagg aatggctcac agagtaagta tagcaagagc actttccttc
     7441 aatcccgata ttttgctgat ggacgaacca tttgcagcgc tagattactt cacaagaaga
     7501 aaaatgcaaa aagaagttgt aaatatccat aaaaatacta aaaaaggtgt agtatttgta
     7561 actcacaata ttgaagaagc tatggaaata gcaaagaaaa taattgtttt tagtaaaaat
     7621 aaaaggatta aacaatttag tgtcgaagat gaatataata gagatttaac taaaaactat
     7681 tatataaact tgaaaaaaga aatattaagg gaattggggg agttttaatt gattaaaaga
     7741 aacaaaaaga ttttagcagt aatgacatct ttaataatgg tgttggttgg gactgtagga
     7801 tgttcaacaa caaatgataa gaaagatgaa cctgcaaaaa aagaggctag tttacctaag
     7861 gaaataaatt taacttatgt aaaatcacca cttaatgttc ctagtatatt agaaaaaaag
     7921 gatgatttat ttggaaagga atttaaaaag gacaatataa aagtcaactt ccatgaattg
     7981 acaacaggac cagagcaaac tcaagcatta gcagcaggtg agctagactt tttacatgca
     8041 ttaggaggaa cgtctgcaat aatagctgca tcaaatggtg ttggtcttaa aattacgaat
     8101 atttatagcc gttcaccaaa aggatatatg cttataacta ataatgataa tattaaatct
     8161 ataaaagact taaaaggtaa aaaaattgta ggtccaaaag ggactatact tcatcaactg
     8221 ttgattgctg cacttgctaa agaaggctat actatagatg atgttgaata tgtaaatatg
     8281 gatattccta gtgctgcttc tgcattagaa agtaaaagtg ctgatgtagc aatgcttgca
     8341 ggtccagtgg cattgaaaac gataaattca ggtgccaaaa tgattgtaaa tggagaagga
     8401 ttagtaagtg gaataatagt tactgctgta agtgatgact ttgctgaaaa atatcctgaa
     8461 ttagtaaaaa gatttatgaa ggttcatgaa gaaactttaa aatatatgaa tgaaaacaag
     8521 gatgaagtga tggatgttgt atctaaagaa gttggtttat ctttagatga aacaaaagaa
     8581 atgtattctt ggtatgactt tagttctaaa ataacggaca aggatataaa agaattagaa
     8641 gatacacagg aatttttgat gtctaatgga atgcaacaaa agaaaataaa tattaaagat
     8701 atgttgtaca atcaaaatta gaatacttta aaatattaaa gtggaaaata cacccttatt
     8761 tattatggaa actgtatggt aaaagagggt gtatttttat tattatacaa aaatacaatt
     8821 aaaaacaact tactatttta tctacactta tgtagtctag taattttctc attttcttac
     8881 ggtgaagtaa aaactttgaa tatgtgtcct cggattgttt tgtgtcacca taaactttcc
     8941 aatatttaat catagaaact tcataattac tatatcccat aaatccaatc acatctttaa
     9001 gaggatatcc taaaaaaata cctatttcat caggaaaaac atcactctta agtttattta
     9061 ctaaatgctc taaataagca ttaacattcg tattttgttt gtatcctaaa aactttaaaa
     9121 agtttactgt ttttttacat tttaattttt ctgataatgc ttttttattt acaaataaga
     9181 tttttaatcc ctttttttct ttatcaataa ctataaaatc tattttctta catttatata
     9241 gatatttata aatatcatta attttttcct ctctatttac atcagtaaac gaaatattta
     9301 ttatttcagc aggtttagag cctaaaaaga ctggacctaa aacctctaaa agccatttta
     9361 tatatgatga ttcaatttta tttttacaac aaaattgtga attacaacaa gacataaaag
     9421 ataacctcct tcaaatgaaa attaatatca agtaattaga ttatactatg aatgataatc
     9481 aatatcaata ataaaattat aattttttta tttaattatt tattcatta
//
LOCUS       DAEQJM010000103         9235 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.105, whole genome shotgun sequence.
ACCESSION   DAEQJM010000103 DAEQJM010000000
VERSION     DAEQJM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9235
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.105"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            447..1652
                     /locus_tag="KRQ43_003385"
     CDS             447..1652
                     /locus_tag="KRQ43_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH2743721.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVGPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNVKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1723..1944)
                     /locus_tag="KRQ43_003386"
     CDS             complement(1723..1944)
                     /locus_tag="KRQ43_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743722.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2085..2684)
                     /gene="recR"
                     /locus_tag="KRQ43_003387"
     CDS             complement(2085..2684)
                     /gene="recR"
                     /locus_tag="KRQ43_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBH2743723.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2697..3047)
                     /locus_tag="KRQ43_003388"
     CDS             complement(2697..3047)
                     /locus_tag="KRQ43_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBH2743724.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3106..4743)
                     /gene="dnaX"
                     /locus_tag="KRQ43_003389"
     CDS             complement(3106..4743)
                     /gene="dnaX"
                     /locus_tag="KRQ43_003389"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBH2743725.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKYSIDENESK"
     gene            complement(4820..5084)
                     /gene="ffs"
                     /locus_tag="KRQ43_003390"
     ncRNA           complement(4820..5084)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KRQ43_003390"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5122..5213)
                     /locus_tag="KRQ43_003391"
     tRNA            complement(5122..5213)
                     /locus_tag="KRQ43_003391"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5177..5179),aa:Ser,seq:gga)
     gene            complement(5214..5669)
                     /locus_tag="KRQ43_003392"
     CDS             complement(5214..5669)
                     /locus_tag="KRQ43_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HBH2743726.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5989..7260)
                     /gene="serS"
                     /locus_tag="KRQ43_003393"
     CDS             complement(5989..7260)
                     /gene="serS"
                     /locus_tag="KRQ43_003393"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH2743727.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKTRLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEYKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7385..7591)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7718..8599)
                     /locus_tag="KRQ43_003394"
     CDS             complement(7718..8599)
                     /locus_tag="KRQ43_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH2743728.1"
                     /translation="MNFLSLAKAASTNSNITKRTLENMLNNFSDNIPNIIYAIIVFVI
                     GIYISKIVRKMVSRFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGVIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFINEKR
                     ILDDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENNIKVPFVP
                     SSLLFNNMSNSNTMDKR"
     gene            complement(8611..9120)
                     /locus_tag="KRQ43_003395"
     CDS             complement(8611..9120)
                     /locus_tag="KRQ43_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBH2743729.1"
                     /translation="MNSDERRSKLIDILKESKCPVKGGMLAEILNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHRNSKEIYDELKIIVDLGGIVKDVIVNH
                     PTYGQITAELNIHSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIETLKEETIEVITK
                     ELEDRGILS"
BASE COUNT         2948 a         1613 c          983 g         3691 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttctttt tccttttttc
       61 aaggacaagt aatactatat catctttatc tattctagtc aatataattt tttacttttt
      121 ttaaattttt tatttatcat gtattcttta tatttaattt ttaaaactta atgctaagta
      181 aacctattta tttcataaaa ctaatatata ttctatgctc tattttcctt tttattctat
      241 atttaaattt tttatttaca agaatatttt taatataaca tatttgataa aattaattta
      301 catttctttc acttgtaatt tttgcaatct tgtattagat taatattaaa aataatttat
      361 caataacctt attcacaaag acagttttta tatatcaaaa tataatacaa tataaatact
      421 atgctacatt ttaggaggat tttattatga gcaaaaaagt attaataatg tctgcttcca
      481 ctggtggtgg gcataatagg gctgctctag ctattaaaga agaacttact tccaaaacac
      541 ttgatggaga gccaattgaa tgtgaaataa tagatagttt gaaattagtt aataatacaa
      601 tggataaaat aatttcaaga ggatacgaaa aatctgctat atatactccc aaagcctatg
      661 gaagtgtata tagattatct gaaacaaatc ttttgtcaaa aaatgaattt aaagataatc
      721 tactaataac attcatggct aaaaaattta aaaagcttat tagaagcgaa aaaccagact
      781 tgattatagg aacacatcct tttccaatga ttgctctaag cacattgaaa aaaaacttta
      841 atttacataa taatgaatca aatgcttaca cagagcattt ttataaacat tatacaaata
      901 ccattaatgt tcctccgctt atttctgtat taaccgatta tactactcat tctacatgga
      961 tacaaaatga aattgattac tatattgttg gtcatgaata tgtaaaagaa ttattggtgt
     1021 ttgatggagt tggaccgagt aaaattagaa catttggaat ccctgttgaa aaatcttttc
     1081 tctctcacag agataaagat attgttcttt ctgagttgaa tttatctcct gataaattaa
     1141 ctgttttact tatggggggt agctttgggg ctggaaatat aaaagagaca cttgatgaat
     1201 tactggatac tgatagagat tttcaaatac ttgtaattac tggtaagaat gaaagcctaa
     1261 aagaaaaaat cgaaaaaaaa cttatgtctc gttatcatga taaaaatgta tgtgttcttg
     1321 gatacactga taagatgaat gatattttag cttctataga tgtattagta agcaaacctg
     1381 gtggacttac tacaactgag gctcttttaa aagatgtacc tatgatagtt ccttattata
     1441 taccaggtca ggaagaagag aatcttgatt tcttatctaa ttgtggtgca gcacttagaa
     1501 ctacaaaaaa atataacttg tcaatattac taaaagttct aatagatgac cctagcagat
     1561 tagaaatgct aaaaagaaat gttaaatcaa taagaaagtc aaattcagcc caaaatatag
     1621 ctaatttaat tttaaatata atttctggtt gataaaataa ataaaatccc tatagtatat
     1681 atattatcta ttagggattt tttattttct aattatttaa tattaaattg gttcataaaa
     1741 gtcttcttca taatcatact gataattttt ataattattt ctaaattcag catttttatt
     1801 tcgtacattt tttttagttt ttttcttatt agaaaaactt atatcctcaa aatcatcata
     1861 tttaggttta tcttttgatt tcattttttt aactcttttt tctttcattg cattatgttc
     1921 ttctaagttc ataattggtt tcatgttgca cccctatcaa aatttttaaa tgatttatac
     1981 aacaaattat acaatacaga agaaatttat tcaataaatc taaatcaaaa ttaatttgaa
     2041 tttaactcaa aaaactacaa aaatcgaggt attaacctcg atttttatat ttctcttctg
     2101 ccttctagtg cttttgatat tgtgacctca tctgcatact ctaaatcgcc tccaacagga
     2161 agaccatgag ctatccgagt gactttgatt cccattggtt ttactaacct agcaatatac
     2221 atggctgtcg cttcaccttc aatagtagga tttgttgcca ttattatttc tttgacttcc
     2281 tgattgccaa gtctttggat aagttccttt atttttaaca tatctggtcc aattccatcc
     2341 attggagaaa ttactccatt taatacatga tactgtcctt taaactctct cgttctctcc
     2401 atagctgcta catctcttgg atcttccaca acacatataa cacttgaatc tctactttta
     2461 tttgaacaca tgctacatgg gtctgtatct gttatattac aacaaattga gcaatatctt
     2521 atttctcttt ttgcatctat aatcgcttta gataaagctt ccacatcatt agtattcata
     2581 ttaataatat gaaaagccaa tctttgagca gtctttcttc ctactccagg aagctttgaa
     2641 aattcctcta taagtctcgt tatgggacct gtataaactt gcataaatac cacctactag
     2701 aataacccag gtatattcat acctccagtt accttactca tttgacttgc ttgtatatca
     2761 tcaatatttc tcaatgcttg atttactgca cttaaaacta aatcttgtag catttctata
     2821 tcatctggat caactacttc tggcttgata gttatatcta taacttcttt tttaccatta
     2881 acttttacag taactgctcc tccaccaact gaagcttcta cttctttact ttctaactct
     2941 tgttgagctt tttgcatatt ttcttgcatt ttttgagcct gctttaacaa gttgttcata
     3001 tttccaccac caggcatcat tccgcctcca aaaccttttt tagccataaa cactattcct
     3061 cctaaactta ttttcatttt attattatat cataatagta ttttattatt tactctcatt
     3121 ttcatcaata ctatatttta tttctaatat ctcttcactc actatgttct ttaatatctc
     3181 ctcaccaatg tcctttttct ctttaacttc aagatttata tctttaactt ctgatgtcag
     3241 tactattttt acattaaaac ttctatttaa aacatctctt attgtttttt ctaaataatt
     3301 tattgtatct tgagagctca gtctagtttt tgcaaaatca aatttatcat caaatataac
     3361 atacaacata ttagaatata cattaaaact ttttacttca cttaagagtg cgtatattgg
     3421 cattttttta tcttttttaa tttgtttaag tatattcttc caagatgact ctataagtat
     3481 aacgtcctca ttttttacat cttcataaac tacattttct tgttttacat ctatttctct
     3541 atcgacctca tactcttttt ctttattatt cccaattttt tcagacttaa agttccccag
     3601 ttcaatcatt ttttctaagt tctcaactct ttttataaga gcttctttac tttcatcaaa
     3661 cattggttga gcaattttca ttatggttat ttccactaaa acccttggat ttgaagatga
     3721 ctttatatca tcctgagtta ttgataatat atttaaaatc cttattaaat catttatatc
     3781 tatattttta gactgaattt taagttgttc tatagtttct tctggtaatg aaattatttc
     3841 atccaattct gatgaaacct tacataccat taaatttcta aaatgatcaa ttaagtcatt
     3901 tataagattt cttatatctt tgccccataa gacaaattca tttaatatct caagagactt
     3961 tttagtgtcc tgctctacaa tacattgaga caattcaaat aattgttcta tatttacgct
     4021 tcccattaat tcaacaacat ctttataatc tatcttactt tctccaaaag acatacattg
     4081 gtctaatata ctaagtgcat ctctaagagc tccttgagaa tttctagcta ttaaattaag
     4141 agctttatca tctatatcaa ttccttcatc ttcacaaatc tttttcattc taagggtcat
     4201 atctttaact gtaactcttt taaaatcgta tctttggcat cttgataaaa tggttgcagg
     4261 tattttgtga ggctctgtag ttgctaatat aaaaattaca tatgatggag gttcctctaa
     4321 ggtctttaat aatgcattaa aagctccttg agacaacata tgaacttcat ctattatata
     4381 tactttatat ttagcattgg ctggagaata tttcacactt tctctaagct ctcttatatc
     4441 atctacacta ttatttgaag ctgcatctat ttctacaaca tccattgtat tatcttttaa
     4501 tacagattca catatctcac actcattaca cggttcttca tttattttat tcaaacagtt
     4561 tactgctctt gaaaaaatct ttgcagtaga tgttttacca gtacctcttg ttccacaaaa
     4621 caaataagca tgtcctatat tatcactata tatttgattt tttaaagtct taataatatg
     4681 atcttgacca ataacatctt caaatttttg tggtctatat gctctatata atgctttatg
     4741 catcttttta cctctcttta gcaaaattaa taaaaaaatc cctcattatc taagggatta
     4801 gtcttttata tattaaatgc tgtacaccat ctatcgactt aattccatag gcgttaccaa
     4861 aacagttagc tcaacttagg cacccccacg gcacacaaaa gtgatcactt accgctgctt
     4921 ccttccggat ctgacggggt tcatgagctt tcattgcgca ggacctaagc atcaacacca
     4981 cttatttagg gcggccctac agaaaataag cctttagatg gaattcaatc ctgctatagc
     5041 ggattgcagg ttacagggca ccgctacctc cccatctagt acagcaaaat tacaaccata
     5101 tttaattact ttcattgttt ctggcggaga gagtgggatt tgaacccacg atacagtttt
     5161 acccatatac tcgctttcca ggcgagcgcc ttcgaccact cgaccatctc tccttaatct
     5221 ctttttctca atgccttaaa aaattcttgc aatatgatcg agcattcttc ttgcaaaaca
     5281 tcaaaagcta cttttacatt attattatta aaataatcta atttaaactc atgctgtttt
     5341 tctatatatg aattttttac atgtcttgtc cctattataa gcttttttat tctagaatta
     5401 actattgcgc cactacacat tatgcaaggt tccattgtaa catataaatc acaatcagtc
     5461 aacctccaac cacctaattt ttctgatgct tgttttatcg ctaaaatttc tgcatgtgcc
     5521 gtagagtctt ttaacgtttc tgtaaggtta tgagctctag ctattatttg attatcttta
     5581 actataatag cacctattgg tgtttctttt ttattatatg ctttatatgc ttcttttaat
     5641 gcttctttca tataaaatga actttccata attcctccca aaacttataa caaacttatc
     5701 ttatcataat tcattttata attcaactta attttatttt gtttatttaa ttattactat
     5761 atatagcgat atttttttta attagttcta aaataatttt tagatattca tacaagagtg
     5821 ttttataaaa atatttagtg ttttatgatg aaaattctgc tgtgtaaatt aacataaaaa
     5881 aactatgaaa ttaatattta taataatttc atagtttttt tatttattgt ttactcataa
     5941 tatattctct tcatcaaagc atactctaca tatacaatta atataaattt attttataac
     6001 atcaacaccc atataaggtc ttaattcttc tggaactact acagaaccat ctgcctgctg
     6061 ataattttct aatatagcag ccaaacatct tcctatcgct aatccagaac catttaatgt
     6121 atgaacatat tctgcttttg attttttatc tcttttaaat cttattcctg ctcttcttgc
     6181 ttggaaatct tcaaaatttg aacaagaaga tatttctaca tatctattgt aacttggcat
     6241 ccaaacttct aaatcatatt taaatgcagc tgtaaatccc aaatctcctg tacatatttt
     6301 tacaactcta tatggaagac ctaacatttg taacatagtt tcagcatcat gagttaatga
     6361 ttctaattca ttataagaat cttctggttt aacaaattta actaattcaa ctttattaaa
     6421 ttgatgttgt ctaactaaac ctcttgtatc tcttcctgct gaacctgctt cagatctaaa
     6481 acaaggagta tatgcacagt atttaattgg aagctctgca acatctaata tttcattagc
     6541 atgtatatta gtaacaggaa cttcagctgt tggtattaag aaatactcta atccttctat
     6601 tttaaacata tcttcttcaa atttaggaag ttgaccagtc cctataaaac tatttctatt
     6661 ggccataaat ggaggtaaga cttctgtata gccatgctta gctgtatgag tatttaaaaa
     6721 gaaattcatt aaagatcttt ctaatctagc tcctaatccc ctatataaag taaaccttga
     6781 cccagttatt ttccctgctc tttcaaaatc taaaatacct agacctgtcc ctatatccca
     6841 atgcgcttta tactcaaaat caaatttagt aggttctccc caagttctta tttgaacatt
     6901 gtcttcatct gtttcacctt gtggtacctc tggatgagga acatttggta ttctcattaa
     6961 tgtatattcc atttttgctt ctacttcttt tactttctca tcaatacctt ttatcttatc
     7021 tgataactct ttcaatcttg tcttttcttc tgttacatct tttccttctt ttattaattg
     7081 aggtattttt ttagaattta catttaactc atttttcata acttcaactt cttgaagtat
     7141 ttctcttctt ttattatcta gttccactac agcatcaagg tcaaattctc tttcacctct
     7201 tctttccata gcttttttga tatcatctag attttctctt attcttttaa tatctaacat
     7261 attaattcct cctaataatt ttgataatat aaattataat tccaattaat ttacaagtat
     7321 tctagctgta aacttttaat ttaaacaaat ttgaaaaata aaaaaagacc tccgtttacc
     7381 ctataaaagg gacgaaaatc ttttatccgc gttgccaccc taattgatta tactaaaacg
     7441 tataatcctc tcagacctat aacgtaggta aaccgtctag ctttaactag aagctctaga
     7501 gtagattcaa aaaccattgt aatgagttct caccatccac tcattctctg aatacaatct
     7561 gttttttact attttccttc accgcttttt aactaattgt tttatttgat aatcattata
     7621 ttatatatat taacatcttt caatactatt attcaaattt ttttagaatt ttctttaatt
     7681 ttttatatta aattcacttt tttacttaat tgaaattcta tcttttatcc attgtatttg
     7741 aattgctcat attattaaat aataacgagg aaggaacaaa tggaactttt atattatttt
     7801 cgtcaaattt atttttgact ttttccatta catcaaagta aacatcccag taatcatcag
     7861 ttttaaccca tggtctagca actatttgca tagtgttgtt tcctatagag tttaaaccta
     7921 taattggttt tgggtcatcc aatatccttt tttcatttat aaaaatttca ttcaatatgg
     7981 acttaactac atcaatatca ctatcatatg aaatattata tgaaaaatct atccttcttt
     8041 tattttgatg tgtgtaatta attatattgt tacttgtcaa ttgaaagttt ggtataatta
     8101 tggttttatt atctggggtt ttaagaacag tactaaatat ttgtatatca gaaactgtgc
     8161 cttctacacc tgagccttga atataatcac ctatattaaa tggcttaaaa aataaaataa
     8221 tcatacctga acctaaattt gataatattt ctttaaatgc taaacctata ctaaatccag
     8281 cagctcctaa tacagctaca actgatgtag tttgtatccc tataacaccc aagcttatca
     8341 atgatataat agataacata gatatgtata ttccatatac aatgaaatta tttacacctt
     8401 tactcattcc atatttgatt aaaaaccttg aaaccatctt tcttactatc ttagatatat
     8461 agatacctat tacaaatacg attattgcat atataatatt tggtatatta tcactaaagt
     8521 tattaagcat attttctaaa gttcttttag ttatattact atttgttgaa gcagccttag
     8581 ctaatgataa aaaattcatt taactcctcc ttatgataat attcctctgt cctctaattc
     8641 ttttgttata acttctatag tctcttcttt taatgtctca attgtatgaa tatgactaca
     8701 ttcagttaga actgataact gtttaaattc atttgtctca accttcttca taaaattatc
     8761 tatatccatt ttagagtgaa tattaagctc tgcagttatc tgaccatatg ttggatgatt
     8821 tacgatgaca tccttaacaa ttccacctaa atctacaata atctttaatt catcataaat
     8881 ttctttagaa ttcctgtgat tcttacattt tatttgcttt gtaaaatatg gttgattata
     8941 tattatatat ccttgaggtg tagctattat ttcaaatcct ctagctctta taagggctat
     9001 atcttgtact attacttgcc tacttacatt taatatctca gctagcattc caccttttac
     9061 agggcactta gattctttta aaatatctat taatttgctt cttctttcat cagaattcat
     9121 attacacctt ctttctaaat caaaaacttt acctatacta tataattcta tattttatct
     9181 tattataaat caatattgat tttatattct atttaatatt aaactttatt gcaaa
//
LOCUS       DAEQJM010000104         9206 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.106, whole genome shotgun sequence.
ACCESSION   DAEQJM010000104 DAEQJM010000000
VERSION     DAEQJM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9206
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.106"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            87..875
                     /locus_tag="KRQ43_003396"
     CDS             87..875
                     /locus_tag="KRQ43_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HBH2743730.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHIGVLFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSVDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEISE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            896..1636
                     /locus_tag="KRQ43_003397"
     CDS             896..1636
                     /locus_tag="KRQ43_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH2743731.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDSLQNAKFKKVGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAVVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            1814..2188
                     /locus_tag="KRQ43_003398"
     CDS             1814..2188
                     /locus_tag="KRQ43_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743732.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKDNKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            2280..3740
                     /locus_tag="KRQ43_003399"
     CDS             2280..3740
                     /locus_tag="KRQ43_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBH2743733.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTIGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIEEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLNVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFETWFESFKAELENAIKK"
     gene            3793..6669
                     /locus_tag="KRQ43_003400"
     CDS             3793..6669
                     /locus_tag="KRQ43_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH2743734.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKILNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILNDKNINDKPIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQEGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRIEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKDKKLKWIRMNIFEDELKVLG
                     VVVDVTKEFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLD
                     NLKYINDTYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRD
                     IINSVKKQMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTI
                     KGEVSEFDINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPK
                     IKTFSSPIDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLS
                     KVDFEEIEDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNG
                     DAVLLYIMPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVISEGVETKGEME
                     TLINLGVDYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            6746..8812
                     /locus_tag="KRQ43_003401"
     CDS             6746..8812
                     /locus_tag="KRQ43_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH2743735.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVYTANRLIDKNKNRYEKVIKCSQGDGGSVTYISPHDSEEEAL
                     YIAKEIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
BASE COUNT         3757 a          866 c         1646 g         2937 t
ORIGIN      
        1 ttgttaaagg ctatttttat taaagatagt ctttttataa tgtcataaat gattagatat
       61 gtataattaa agaaaggagg gaatagatga caactttaat ttttttcata gtggggatag
      121 catctttggt agttgctttt gttattgatg ggggacatat tggagtatta tttgtatttt
      181 catcagcact tgttgtgttt ggtggaacta taggcgctgt tggagcttcg actccattcc
      241 ctgtgtttaa aaagtctata aagataatgt tattagcttt taaaaataaa aagcctaata
      301 acatagaaaa tataatctat ttcaaagaaa ttgcaacaaa ggctaggaaa gaggggcttc
      361 ttagtgttga caaagaaata agtgagaatg atgaattaga cccttttatt agaaaagggc
      421 ttgaacttat ggtagatggg gtggatgcag ttactataag aaatatattg gaatcacaga
      481 tacagataac atcaaaacga cataaagaag gaatagcaat ttttgattca gcaggtggat
      541 atgcacctac actggggata ataggtacag ttatgggatt agtacatatt ttaggtaatc
      601 tttcaagtaa tccagatgca ttaggacctc aaatttctgt tgcatttttg gctactttgt
      661 atggtgttgg ttctgccaat ttaatatggt taccaatagc atcaaaactt aaggctataa
      721 atcaacagga aataagtgaa agacttttgg tgatagaagc aatattatcc atacttgagg
      781 gtgataattc taatttaatg acagaaaaat taaaaatatt tttaaattca aaagaactaa
      841 ttgaacttga agaaattggt ggtagagctg aataatataa aaggatggaa tgtttatgtt
      901 gtatgatgaa gatgaaaaag aagaaaacaa tgagcgatgg cttttaactt attcagacct
      961 cataacatta cttatgattt tctttgtaat aatgtattct atgagtaatg ttgatgcgga
     1021 gaaatataaa caattatctc aatctctaaa ttctgctttt ggtggttctt ctggagttat
     1081 tgaaggtggt aatagcaaaa tagaaccagt agttgaacca ggaagtaatg atttagatag
     1141 tttacaaaat gctaagttta aaaaagttgg tgaagaaatc cagaagtatt taaatgaaaa
     1201 tggtatggct aattcagtat cattaagagt tcaagataga ggattagtaa taagccttaa
     1261 agatacaata ctatttgata caggaaaagc agttgtaaag gataattcta gagataagat
     1321 tattcaaata ggtaagatgt taaatgaaat gaatagttac atgagagtag aaggtcatac
     1381 agacaatatg tctataaaaa attcagagtt taagtcaaat tgggatttat cagttatgag
     1441 agcaaccaat gttgttcaac ttcttattga caatgcaggt atagcaccag ataaattatc
     1501 tgctgtagga tatggtgagt ttagaccaat agcagaaaat tcatctgaag aaggtaggtc
     1561 aaaaaataga agagttgata tagttttagt tgatagtaaa tatgataatg tagaaaatgt
     1621 ttcaaaggat aaatagttaa attagctgtc tcaatacaga attaattcta aaggagatgg
     1681 cttttttatg cgaaaattaa aaatagatac atagtaagtt acctttttgt aggaatatat
     1741 ggtatcttaa atatataata tttaaataat atataagctc aattaaaaaa attttataga
     1801 ggatgggaaa taaatgggga ataaaaataa aaatacgaaa tataaagata aaacaagaga
     1861 aagatataat aaaaaagttg agaatttaaa taaagaaaaa ttaaataaag ataataaaca
     1921 gtctaagaag gtagataaga ttgatgatat tattaataaa tctagtattg tattatgtgt
     1981 acttctagtg gtgttttcat tactttactt atttaaattg gttcaactta atataataat
     2041 gatactttta gtaattacag tagctattca acaaggattg gtgtcatttg gtgcatttag
     2101 aaataaaaat tatgtaaaag ctttattttc tatatttgta atagtatgtt tcttaattgc
     2161 ttttaaatat gttgtaaatc ctgtttaaat atatcaataa acgttctata attaatataa
     2221 atagtgaagt tacagtttta atgctattat aaattttata atttgaagga gtagatttta
     2281 tgaataggtg taagtttgca aaattaatta tcacatcaat gattgtttta ttacttacag
     2341 gatgtagttt aaaaaaggaa gataattata agttagaccc agaaaatccg acatcaatac
     2401 aaatttggca ttattataat ggacagcaaa aaatggcttt tgataagctt gttaaggaat
     2461 ttaatgacac tataggtgct gaaaaaggaa ttattgttga agcgtttagt caaggtaatg
     2521 tagttgattt atcagagaaa gttttagatt ctgcaaataa aaaagttggc tctgaagatg
     2581 tgccaaatat atttgcagca tactcagata ctgcatatga aatggataaa ttagggttac
     2641 tagtagatat ggataagtac ataagtaaag aagaattaaa tgaatacata gacgaatatg
     2701 tagaagaagg cagaataaat tctaaggatg agtttaaact tttcccaatt gcaaaatcaa
     2761 ctgaaatttt gatgttaaat aaaactgatt gggataaatt tgcaaaagct acaaattcaa
     2821 atataaatga tataaaaaca attgaaggat tagtagagac atcaaaaaaa tattatgaat
     2881 ggacagatag tttaacgaaa gagcctaatg atggtaaagc attttttggg agagatgctt
     2941 tagcaaatta tattattata ggaagtaaac aactaggagt agaaattttt tctgttaaag
     3001 atggtaaagt tacactaaat attgaagaaa aagttatgaa aaagctatgg gataatttct
     3061 atgtaccata tataaatgga tattttgctt cttatggtaa gtttcgttct gatgatgcaa
     3121 aaacaggtga tatattagct cttgtaggct ctagttcagg agcagcatac tttccagata
     3181 gagtaatgct aaatgataat gagagttata atattgaaac atctgttttt caagcaccac
     3241 gttttaaagg agaaggaaaa tatgctgtac aacaaggtgc aggaatggct gtaacaaaat
     3301 ctactaaaga agaagaatat gcatcagtag aatttttaaa atggtttaca gataaagagc
     3361 ctaatataaa attctctatt gcttctggat atttaccagt aaagaaaaaa acgaatgatt
     3421 tgaatgttat aaaagaagtt atgaagaaag ataatttgag tttatctgat aaagttgaag
     3481 gttcaatagc ctcatctatt gaacaaatta acagttgtaa tttatacact aataaagcat
     3541 ttgatggtgg aactaaagct agacaaatac ttgaatattc aatgcttgat aaagctaaag
     3601 aagattcaaa taaaataaat gaattggtaa aaagtggaac ttctaagaag gatgcggtag
     3661 cacaatttaa taatgataag aattttgaaa cttggtttga aagttttaag gctgagcttg
     3721 aaaatgctat aaaaaaatag atgaattggc agttagtgtg tagacaagca caaaggtata
     3781 ggtggaataa gtatggaaaa caatctaaga aaaaacaatt caataatgaa aaagatgata
     3841 tttcccctaa ttattgttat gctaattcaa acaagtttat tttgtgccac aattttatgg
     3901 ggaggaacta ttaagaaatt aaatgataat tcgtttgaca tcttaaatga aagagtaatt
     3961 aatcgtaaaa attatataca aaatgaaatg ttacaaagat ggtcaaatac aagtgaaacg
     4021 gaagctacaa ttaattcctc tgtaaaaaaa atattaaatg aaaaaaatgc cttaattgag
     4081 gatgtaggca acaatgaaga aattaacaaa gatattataa aaagcatatc aaatgattta
     4141 atatatcttt tgagaaaaaa ctctgttaca ggagctttta taattctaaa tgacaaaaat
     4201 attaacgata agccaataga tagtaaaggt gaaataagta ggactggatt gtatataagg
     4261 gatttagacc ctaagtttaa tccaaatgat aattctgatt tgttaattga gagaggttca
     4321 tcagatatag caagaagttt tggaatatct atggacagtt attgggaacc taaattttca
     4381 tttaaaagtg aaaatgagca agagggagat gatttttttt ataaaccatt tagagctgca
     4441 attgataatc caaacgtatc aagttctaat ttgggatact ggggaagtaa gtttttattg
     4501 acaaatgcag gtgataggct tatgacatat acagttcccc ttatttatga agatggaact
     4561 gtatatggag tacttggaat agatttaagt gtaaattatt taagagaatt acttccatac
     4621 tcagagataa atggaaataa aaaaggtaat tatattttag gtgtagatag aaataatgat
     4681 atggcctttg aaaatgtaat ttcaaatgga tactcattaa aagaaaaatt ttgggatggt
     4741 ttacattcta atttagagca gaaggaatcg tataaaaata tatataagat taaaaataaa
     4801 gataatgaat gtggtaatgg caacatttat gctagtgtac aatacttaga tttatataac
     4861 tccaatactc catttgaaaa tgaacgttgg gctcttttgg gtattattga agaaaaaagt
     4921 cttttgtcat tttcaaaaag gatagagaaa ttagttataa tatctatagc aatttcttta
     4981 ttaataggtc taataggtat ttacattgca tcaagattat ttacaaaacc aattgttctt
     5041 ttagccaaca aagttagaaa cagtaatcca tcaaaaccag taaatcttga taagataaat
     5101 atatctgaaa tagatgaatt atcttcagct atagagttac tcagtgcaaa tgttgcagat
     5161 tcttcatcaa aattatcaca gattattgaa atggtagata tgccaatcgg ggcttttgag
     5221 ttatacaaaa acgcagagaa tgttttttgt acaaaagata aaaaacttaa gtggataaga
     5281 atgaatatct ttgaagatga gctaaaggtt cttggtgttg ttgttgatgt cacaaaagaa
     5341 tttattgaga aaaggaagat agaatatgaa agagattttg atattttaac gaatctttta
     5401 aataggagag cttttcattc acagatacaa gaaaaattta agaataaaga tgaacttaag
     5461 atagcagcat ttattatgtg ggatttagat aatctaaaat atattaatga tacatatgga
     5521 catgatgctg gtgatgaata tattaggtgt gctgcagaca tacttaagaa gtttatatca
     5581 tggaatggta tagtatctag actttcaggt gatgagtttt atgtatttat atatggatat
     5641 gaaagtaaag atagtataag agatattatt aattctgtta agaaacagat gaataatacc
     5701 ttattaaaac ttcatgatgg aacagaattt aaaataaggg catcagcagg aatttcctgg
     5761 taccctgatg attcaaccaa ctatgatgaa ttaatgagat acgcagattt tgctatgtat
     5821 caaattaaaa atacaatcaa gggggaagtt agtgaatttg atattaatat atataataag
     5881 gattcattct tattgagtaa tagagaagaa ttaaacaagt taattgatgg tcaattagtt
     5941 gagtatgcat ttcagcctat tgtagattgt aaaggtaaag tatttgcata tgaggcactt
     6001 atgagaccta aaataaaaac ttttagttca ccaatagatg taattagatt agctcgttca
     6061 cagtctaaat tatatcaaat tgagcgtatt acatggttta aagcacttaa atcatttaaa
     6121 aaatacaaag aaaaatttgg cgattgcaaa ctgttcttaa attctattcc taataataat
     6181 ttatcaaaag tagattttga ggaaattgaa gatttatatg gtgaatattt aaatagagta
     6241 gtattagaaa taacagagaa tgataagatt aatgaagatt ttattgagaa aaagaaagca
     6301 tatatagacc attggaatat agaaattgct ttagatgact ttgggacagg ttacaacgga
     6361 gatgctgtac tattatatat aatgccagac tatgtaaaga ttgatatgtc tattgtaaga
     6421 ggtattgata aagatgaaaa cagacagaaa atattaaaaa atcttatctc atattctaac
     6481 gaaagaaata ttaaagtgat atcagaaggt gtagaaacaa aaggtgaaat ggaaacactg
     6541 attaatcttg gagtagatta tatgcagggt tactatatta gtaaaccatc atttatacct
     6601 gaagatataa gtgacaaaat taaaaaagag ctcaagatat gtcatgaaaa taggaatgat
     6661 gtggtttaat agaggaaaaa ttaaatttat ttttatgaac ttttagttta taattaaaaa
     6721 gaaaataata taattataaa ttaaggtggt ggagctaata atcacaacaa acatagatat
     6781 aagaaagtta aatgaaaatc aattagaagc agttgaacat atagatgggc cttgcatgat
     6841 acttgcaggg cctggttcag gtaagaccag agtaattaca tatagaatag ccaatatggt
     6901 tgtaaacaaa aatatagcac caacaagaat cttggcaata agttttacca aggcatcttc
     6961 aatagaaatg aaaaatagag ctttgaattt aagtgatgat ataagactta ataaggtaac
     7021 ctatggtact tttcactctg tattttttaa aattctaaga tactttgaaa gatacaattt
     7081 agacagtata tttgatgaaa agtcaaagcg aatgacaatc aaggcaatcc taaaaagttt
     7141 aaatatagag aatgctgatg atgatgagaa tataggacaa gttataaatg aaatctccta
     7201 tgtaaaaaat gaacttatgg ataaaaatga atttaattca gaagtattaa caaaagatga
     7261 gtttttaaaa gtatacaact tatacgaaga acaaaaatct aaagttaaca aaatagattt
     7321 tgatgatatg cttataagaa cttattattt acttttgaac aataagtctg cactagaaat
     7381 ggttagaaat gtgtataaat atatattgat agatgaattt caagatataa ataaagtaca
     7441 gtttgaagtt ttaaagttaa tttgtagccc attaaacaat atatttgcag ttggagatga
     7501 agaccaaagt atatatggat ttagaggtgc tagaccagat tttttgcttg aatttgaaca
     7561 atactttaat aatactaaaa aaataatatt agatataaat tataggtcta aaagtgagat
     7621 agtgtatact gcaaatagac ttatcgacaa aaataaaaat agatatgaaa aagtcattaa
     7681 gtgtagtcag ggggatggag gaagtgttac ctacatttct ccacatgatt cagaggaaga
     7741 agccttatat attgccaagg aaataattga cgaaatacaa aaagattatg tagagtattc
     7801 agattttgca gtaatttata gaacaaatat acagtcaaga gcattagtag atgtatttat
     7861 ggatatgagg attccatttg tagtaaaaga ctcagtaatt acaatatatg accattgggc
     7921 aagtcaagat atactagctt atttaagaat aggtattaat ccaaaatcaa ataaagattg
     7981 gttgagaatt ataaacaagc cttttagata tatatccaaa gacagtataa atatggttaa
     8041 ggatgaaaaa gactttataa cagcattaat aaataagtgt aatcttcatc ctaaacaagt
     8101 taaaacaata aatgatttgg aaatagattt aagttattta aatactttaa atcctaaaaa
     8161 tgcaatatct tatattagaa ctagtcttga ttatgataga tacgttttag attattgtag
     8221 caacagaaag ataaaaacta atggacttgt agagatatta aatgaacttg agagttcagc
     8281 aactaatttt aatactgtta cagagttttt agagcatatt gatagagtaa agactgagtt
     8341 aacggaaaat aacaagaata agcagactga gggtgtcata tttacaacta tgcatagtgc
     8401 aaaaggatta gaatttagaa atgtttatat tataggtgta aatgaaggaa caatacctca
     8461 tgaaaaatca tatgatattt gtaaggaaga gaaaaaagaa gaacaattag aagaagaaag
     8521 aagacttatg tatgttgcta ttacaagagc tgaagaaaag ttatgtataa gctctacttt
     8581 aaataagtat ggtaagaaag ttgataaatc attatttatt aatgatataa aatctccaac
     8641 gaaaaaagaa attgacagta ttggtgtagg ggataaggta taccataaaa aatttcatga
     8701 aggagaaata attaaaaaag atggaattat gtttacaata aagtttaaag atagagagcg
     8761 aatcttggat ttgaaaactt gtttattgaa gaatataatt tatactattt aatttagaat
     8821 ctaaatttag atagaaatat aatgtattat ttattatgtg caagacaaat agatatgtgt
     8881 aaaatgtatt atttaactta ttagaaaaag aaataaggat ttaatatatt atttatagtt
     8941 gtttagaaaa agcaacaatg tggaaaatat tatttagtat tattaaagaa aagcaacaat
     9001 gtgaaagata ttatttagtg taatttaaga aaaagcaaca atgtgaaaga tattatttag
     9061 tattattaaa gaaagagcaa cagtgtgaaa gatactattt agtattatta aagaaaaagc
     9121 aacagtgtga aagatattat ttagtgtaat ttaagaaaag caacaatgtg aaagatatta
     9181 tttagtattg tttaagaaaa agcaac
//
LOCUS       DAEQJM010000105         8982 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.107, whole genome shotgun sequence.
ACCESSION   DAEQJM010000105 DAEQJM010000000
VERSION     DAEQJM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8982
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.107"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            167..823
                     /locus_tag="KRQ43_003402"
     CDS             167..823
                     /locus_tag="KRQ43_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743736.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(1293..2564)
                     /gene="sleC"
                     /locus_tag="KRQ43_003403"
     CDS             complement(1293..2564)
                     /gene="sleC"
                     /locus_tag="KRQ43_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HBH2743737.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIVAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGADTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            2809..3525
                     /locus_tag="KRQ43_003404"
     CDS             2809..3525
                     /locus_tag="KRQ43_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HBH2743738.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            3604..4914
                     /locus_tag="KRQ43_003405"
     CDS             3604..4914
                     /locus_tag="KRQ43_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBH2743739.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            5014..5550
                     /gene="lepB"
                     /locus_tag="KRQ43_003406"
     CDS             5014..5550
                     /gene="lepB"
                     /locus_tag="KRQ43_003406"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH2743740.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            5716..6252
                     /gene="lepB"
                     /locus_tag="KRQ43_003407"
     CDS             5716..6252
                     /gene="lepB"
                     /locus_tag="KRQ43_003407"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH2743741.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            6262..7017
                     /locus_tag="KRQ43_003408"
     CDS             6262..7017
                     /locus_tag="KRQ43_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HBH2743742.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDIRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVREG"
     gene            7091..8758
                     /locus_tag="KRQ43_003409"
     CDS             7091..8758
                     /locus_tag="KRQ43_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HBH2743743.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVILIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
BASE COUNT         3350 a          941 c         1672 g         3019 t
ORIGIN      
        1 gatagagtag taagaaaata aatagataaa gggatagaat aaatttaaat atggaaaatg
       61 aatatctaat aataagtgat taataaataa ttgtagatag attgtaaatt aaataaatct
      121 ttaatagaaa ggagaactat ttatatatta aatagtattt ataaatatga aaaaaggcga
      181 ttttatatgg agtggagttc ttatttgtat tattgctgtc ttagcaatac caagtagtag
      241 agaagtattt atggaagcaa caggtgcaca tccatatatt gggggttttt taaagtttgc
      301 tgtattagct acaatgggag atttacttgg tgctagaatt ttgtataagg attggaaaat
      361 accagtagga gtattttata gagcaatagt ttggggaata ataggtgtag ttaccacata
      421 tggaatgtca atctactcat caggtgtagg tcaagcacaa gtggatggta tgcttccatt
      481 tgagggaata gcttttgcaa atgctctatt taagagtgca actatgaata tactaatgtc
      541 accaactgta tttttattcc ataaggttat ggactgtttt atagataaaa aatatgaggt
      601 tggaaagggg attaaggtaa aacttaaaga tgtggtaaat attgtggact ggaatgctta
      661 ccttggtttt agtgttttaa aaactatacc atttttctgg ataccatgtc atacaattgt
      721 attcttattc cctgctgagt atagagtaat tgcttctgca tttgcatcta tagctttagg
      781 tctaatattg gctttagcta ataagtctaa agttgcagtt taggttcact gatgaagata
      841 atagtattat ttaaattatg aataactttt taaattaata ttatttatat ttataataaa
      901 taataattta gataagaagg aatattctaa gtgatagata gtgttttaaa taataaggag
      961 taatattcta agtgagaagt agcattttaa ataataagtg agattttaaa taaaaagtaa
     1021 gcttttcgtt agaatagcat tttattaaac ttaaaaataa atataatatt ttaaagaaat
     1081 ctaagttgct aagcactgtt tttaagaagc ttaaaatccc ccatttaaag ttttaagatt
     1141 ctaaaaaaac aagttataac taaaaaatgg ctgttaagac tacaatactt ataagtaaaa
     1201 atacttatgg tatatattag ttcataacag ccatttttat tttaaattaa taattttatt
     1261 caataatttg agtttatgtt ctaaatcaag ctttaaatta aaggatttaa agaagctatt
     1321 ctagttgtag ctacataaac tctggatatt tcataccatg ttttaaaatc tactactccg
     1381 ctttgaggta aaccaaagat tccttggaat atcttaacag cgttttctgt atctgctcca
     1441 tagataccat cttctataac ttttggtaca gctggataag aattagatat agcatttaac
     1501 tgattttgta tggttctaac atactgccca gaagaaccaa cttgtagtgt agtaccaggg
     1561 aatgacactg gtacaccact tactataggt gctctttcaa atactatctc atctccatag
     1621 aaatatctta ggatactctc atagtcatat ccttggtcac ctaagtcttt actgccccat
     1681 tgagtcattt ggtcaggaca ttgagatttt tgtccatcac aatattgtgc taatagtggc
     1741 tgtcttgatg taggaggtct ttttataaaa gtattaaaaa tagcatctac aactacgtta
     1801 attggttcaa ataagtttct attatttata aacttatggt cgtatgctgt tgttgaagtt
     1861 attgtaaagt tatatccttt atttctatac cattcagtaa agactctatt taaagtaaat
     1921 gatattatag ctattacatt tgcatagatt gtctgttcag gccaagttga atatatttca
     1981 gatgacgcta tgtttttaat gtactcttta aatggaatcc aatagtttgg agctgatgaa
     2041 tcttctggca aaccatcatg aactactata aattcaggca ctacagggtt atctaataca
     2101 acgaaaccag taggaggtgg taatggtttt aagttacttt ctggaatctt aggaggataa
     2161 gtaccatata gagtatgttc tcctatgtca aaaatcaact cactttgtct tgagaaagaa
     2221 cgcttacttc ttgttctagg agacatggga actccttgtc ttgctacaat tgtagctaac
     2281 aactgcgttc cttctatgac aactgtctca tatccatctg ctatggcttc cactatatac
     2341 tggctataag gtctaacatc agatggctgt agagagtaat ctacatctgg tgctggtaat
     2401 actaaaccag tcacttgacc agattcatta cttcttaggt tttggtataa agttgatgag
     2461 ctttggctac cattagacat tgaatatatg tttactactg cattttgaat aggtctattg
     2521 ttagtagcat caattatgct tactgttaag aaaccatctt gcatcaaatc accctttctt
     2581 taaatgaatt tagttccctt atatttcaag atatgaatat agcttgaaat ttgttaaata
     2641 atatagatat aaatttaaat ttttttgagt atttgagtat atttgtattt aaataattta
     2701 aaataattta atgtatattt tagtatgtat ttaaaacaca aataagctaa aaataagtag
     2761 atgatataaa tcataaataa atcaaaaatt ttgaaaggaa aataatctat gaagctagat
     2821 ttatttttat tagcaatagt tcctatattg atagggatgt tttggataag gtctaaagat
     2881 agatattgta gagaacccct aatccatcta attaaatttt ttttaatagg tgcttttcta
     2941 agtgttataa ttatactttt agaaaattta ctgatgaagt ttaatgtatt tgaagggtat
     3001 tcagaactaa tatatgtatc atttgtagtt gcaggacttg tggaagaagg tgtaaaagct
     3061 ctgatactga ttcctgccct aattaaagaa aaacacttta ctgaaaagtt agatggtatt
     3121 atttactctg tatttttagc tttaggattt gcaacaattg aaaatatggt ttatattttt
     3181 tctgaaagta gaaatctagc actgcaagtt ggtattaata gggcagttat ctctatacca
     3241 gctcatgtaa tgtttgcaat tactatgggc tactatattt ctaagtataa atttgaggga
     3301 aataaaaata aaagacgtga gtatttgttt atggcagtgt taattccaat tttattacat
     3361 ggagtttttg atttcatatt gatgatagaa tatagatggg ctattatatt acttatagtt
     3421 tatgtaataa ttttgtggaa gataaatctt gataaacttg agaaatatat gaatcactct
     3481 aaaaaagtgt ttttcggtaa tcttaggaaa aagaagaaga aataaaattt aaaggaaaga
     3541 cataaataat taaagtataa taaatgacac acaagtaaag cagattgaag ggggattata
     3601 gatttgacag aattaccaaa ggaattttta gaagatattg aagaaatact aaaagatgaa
     3661 tatgatgatt ttataaaaag ttatgaggaa agtaagacta ctgggcttag aataaatact
     3721 ttaaaaattg acaagaaaaa attatttgat ttggagttgt ttgatttgaa tcaaatacca
     3781 tgggcagaag aaggttttta ttatgatgat aaaattgaca gacctggtag aaatccactg
     3841 catgaggctg gagcatacta tttgcaagag ccttctgcaa tgagtgtaat accaaaggca
     3901 gatattaaag agggtgaaaa agttctcgat atgtgtgctg ctcctggtgg aaaatctaca
     3961 tatatactat ctaagctaaa cgatacaggt ttattggttt ctaatgaaat taatgctagt
     4021 agaattaagg ctctagggga aaatttagag cgatttggag cgagaaattg tattataaca
     4081 aacaccgatt ctaatagctt aagaaagacg tttaatgggt attttgataa ggttattata
     4141 gatgcacctt gttctgggca aggtatgttt aggaaggatg aggttgccat atcagattgg
     4201 agttatgcaa aggtagtaga atgtcaatcc atccaaaaag agattatcag agatggatat
     4261 aaaatgttaa agaaggatgg cattttaatt tactcaactt gtactttttc aagggaggaa
     4321 aatgagcatg ttataaatga gtttatcagt gaatatccac atgcagaact tattgaaatg
     4381 gaaagattat ggcctcataa gataaaggga gaaggtcatt ttgttgccaa aataaaaaaa
     4441 ttagaagaag aagaatgtaa tgtcaaagaa ttaaaaataa aaaatttaga taaagaaata
     4501 aaggattata gggagtttga aaagaaattt ttaaaggttg atttttatag taataaaaaa
     4561 aataaatttt atttaagagg agaaaatttg tacctacttc ctgaaatata tccagatacg
     4621 aaaaaactaa aagtattgag atacggtttg catttagggg ttttaaagaa gaatagattt
     4681 gagccttctc atgcactatc tcattactta aaagttgaag atgtaaaaaa tgttgaaaac
     4741 ttcagtgtac agagtgaatc aattcttaaa tatttaaaag gggatgttgt gaattctaat
     4801 gatagtagag gatgggtttt ggtttcggtt gaaggaatac ctttaggttg gggaaaagaa
     4861 tcttctggtg taattaagaa tcattatcct aaaggtctta gaaaagtatt ttaaactatt
     4921 agaaaaaaga agtataatat ttatattgta ggtttatggt agattatttt gctgtagatt
     4981 gacttaatat ttaacacaga ggagacgatt ttagtgggtg aagcagttaa aaaagaagtt
     5041 gtagaatgga taaaagtgat tgtcatagct cttgttttgg catttgcaat aactcgtttt
     5101 atagtgccaa caatagtcaa aggagaatca atgtatccta cattagttga acgtgattat
     5161 ttgatagtta acagaattgc gtacaaggta ggagagccaa aatacaaaga tataatagta
     5221 tttaaaaccg acttaacaga ggaaaatgga aagaaaaaag atttagtaaa aagagttatc
     5281 ggggttcctg gtgaccatgt aaaaatacaa gactccaagg tatatgtaaa tgataagttg
     5341 ttagatgaga cttcctatat acataataat cgtactgatg gagatattga tatcgtagtt
     5401 ccagaaggaa aattatttgc aatgggagat aatagagaaa aaagtttaga tagtagatac
     5461 gatgaggttg gattggtcga cgagcatacc attttaggaa aggttctagt cagattgtat
     5521 ccattttcta agataggaac tattgactaa acatataaaa tttggagcaa tcgctgatta
     5581 gctgaaatca ccagaccata cacaatagtt gtctatataa aaaagacaac accttattta
     5641 gtagacttat ctaaaagata gtgtttaaga gacattatca ataaagataa tataactata
     5701 aaggagaatt tgtgaatgaa tgaaactatt aaagaagaga ttgtagagtg gataaaaata
     5761 attattactg cacttttttt tgcatttatt ataactcgtt ttataaaacc aacactagta
     5821 aatggagaat caatgtaccc gacacttaaa tcacatgatt atttggtagc aaataggatg
     5881 acatataagt tatcagaacc aaaatgtgga gatataatga tatttaagac tgatttatta
     5941 caagagaatg gaaggaaaaa agagcttgta aaaagggtta taggtgttcc tggtgaccat
     6001 ctaaaaatta aggattctaa ggtttatata aatggtaagt tattaaatga agtttcatat
     6061 atacatgata attatactga aggcgatatt gatatggtga ttcctaaggg aaaagtattt
     6121 gcgatgggag acaatagaga agttagttta gacagtagat ataaagaagt gggattggta
     6181 gatgaagaaa atattaaagg aaaagttatt ttaagagtat ttccttttac agatataggt
     6241 atttttgagt aggtgatttg tatggcagtt ggtatagcgt ccttattgtt taatattgag
     6301 gaggctttaa acatttgtga gagtataaag caaataactc atttagagat tggaattgac
     6361 aatatatctg aatgtagcga gttatgtaaa tataaagaga gaatttctaa gttaggatta
     6421 tctataggga tacacttgcc tatggaatta aatacttgcg aaaacataga gtatatacga
     6481 aattcatgga taaattttat tgagaagata gaatttgaac taaaaggatt tgatataagg
     6541 tattttaacc ttcatttggg atatgttatg acaaatagag ttagaaagaa tagagacaaa
     6601 tatttaggaa atagtgtgga ttttttagat aaattaaata caaattcata tgtatgtata
     6661 gagaatactt attcaaaagg tggggatttt tcaaatattg gaaatatatc ttatgatttt
     6721 gaatatatat ttaagaggat taaaaattct aagatttgtt tttgttacga tactggacac
     6781 tgtttaattg atgaggatgc ttatgtaaag aacttaaagg ataaaataag actgatacac
     6841 ttaagtgata atgatggtat caatgataca catgttggta taggaagagg aattttatct
     6901 gaagagggga ttaaagaggt cttaacatta gatgcagaat atttagtatt agaaataaat
     6961 tacgaagaca ttgaagatac tataagtaaa ttgaataata ttgtaagaga gggttaaata
     7021 cctctcttta tcttgttgat atgcctcatt aactaaaatt tatattcatc aaaaggaagg
     7081 agatgttgaa gtgaaaaaaa taaacttaaa aatagaagga aaagataagg aatattcatt
     7141 agaagaaaat tcccctggaa tcagattggg agatatagcg aaagaatttt gtgatgagca
     7201 taagggttat ataacacttg cagttgtaga caataaacta aaagagctaa attgtagagt
     7261 taagaaggat tgtgagataa attttttaga cactactaat gaagatggag agagagttta
     7321 ctttagagtc atgtcattta tatttgtaat ggcttgtaga gaaatctttt gggatagcag
     7381 agttacaata gaacattcac tatcagatgg gctatattgt gaagttcata tagatagaaa
     7441 gcttaaagaa gcagatgttg aaaatataaa aaacaagatg aaagagatag taaacaacga
     7501 ttatgttata gaaaaaattg aagttacaag aaatgaagct atttctatat ttgaaaataa
     7561 tgaaatgtat gaaaaggcag agcttttgaa atacaaagag tatgatagtg ctaaagtata
     7621 taagtgtaga aactatatag accattttta tggttatatg ttgccatcaa ctggttatat
     7681 aaaatcattt gatattaagc tttataatgg aggcgttata attttagggc ctagtgaaga
     7741 agataagact cttcctatga agtttgtacc tcaacctaag ctatcaagtg tatattatga
     7801 agcagaagaa tggtcaagac ttatgggaat tgacaaggta gtatctctta acaaaataat
     7861 agaaaacaat gaatatggag atataataag gacattcgaa gcattgcatg aaaagaagtt
     7921 atcccaaata gcggatatga taaaggatgg caataagaga gtaattttaa tagcagctcc
     7981 atcttcatct ggaaaaacaa gttttgctca cagattatca atacatctta gagtaaataa
     8041 tttaaatcct atttcaattt ctttagatga ttattttata gatagaaaac atactccttt
     8101 agatgaatat ggaaattatg attttgaatc aatttatgca atagatttag agaagtttaa
     8161 cttagactta aagaaacttt tagctggtga agaaattgat gatataagat tcaattttaa
     8221 agaaggtaag agagaataca ctggtaaaaa aataaagata gattcaaatc agccaattat
     8281 attagaaggt atacatgggc taaatcctat tttaacatca tctataccag atgaagataa
     8341 atttaagata tacataagtg cccttactca aataaatttg gatgaccata atcgaatccc
     8401 tactgctgat ttgagaatga taagaagaat tgttagagac tataatttta gaggatatag
     8461 tgctgataat actattttac aatgggcatc agttagaaga ggagaaaaga agaatatatt
     8521 cccgtaccaa gaggaggcag atgctatatt taactctgct tgtgtatatg aattagcagt
     8581 tttaaaacga tttgcgaaac ctttgttgga agagataaag gaagataatc ctgcacatat
     8641 tgaagctact agattactaa agtttttgca gtattttgtt gaattggacg atacttctga
     8701 cataccaggt atttcaattc ttagggaatt tattggagga agtaaaatag ttgattaata
     8761 tgtgtattat agattgtttt atgaagatta aatggcatag caagtagtgt gattggttta
     8821 tgttaagtat attaagtgta aagtggagaa ttaaattgat acagatttta aagtttgagt
     8881 tgatatataa aaaggcttgt tttatacttt tgtatgaagc aagcttttta ttttaaattt
     8941 tacttttttg tttaatattt tgttagttta tgtgataatt tt
//
LOCUS       DAEQJM010000106         8588 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.108, whole genome shotgun sequence.
ACCESSION   DAEQJM010000106 DAEQJM010000000
VERSION     DAEQJM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8588
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.108"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     regulatory      895..999
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            1209..3683
                     /gene="gcvPA"
                     /locus_tag="KRQ43_003410"
     CDS             1209..3683
                     /gene="gcvPA"
                     /locus_tag="KRQ43_003410"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HBH2743744.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISTLKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHHETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            3683..5140
                     /gene="gcvPB"
                     /locus_tag="KRQ43_003411"
     CDS             3683..5140
                     /gene="gcvPB"
                     /locus_tag="KRQ43_003411"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HBH2743745.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPLIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            5563..7920
                     /locus_tag="KRQ43_003412"
     CDS             5563..7920
                     /locus_tag="KRQ43_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBH2743746.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKDDFLYSGSFVVSGEAFVRVENIGKDNYANKIVNDAKISKKHNSQLRNSLN
                     SILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKIRIEVEKYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDNDIYEAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(8006..8323)
                     /locus_tag="KRQ43_003413"
     CDS             complement(8006..8323)
                     /locus_tag="KRQ43_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBH2743747.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         3385 a          915 c         1483 g         2805 t
ORIGIN      
        1 ttacagtact taattgtact gaaaaaaact ggggttgctg gctttcggag tgggctatcc
       61 cgtttttatt tttttgtata tataatagat tggcacttta gtataaggtg ctttttttat
      121 aggcaaaaac agtacattta tttctgtttt attatcattc atctattaga atatacttta
      181 tttaagaatg tgttaataag cagtgttcac attcttgata aaatgtggaa taatatgcct
      241 accaataagc atttggtgta taagtaagag tatttatata gttgattgtg aaatgagtac
      301 aacaattctg tacagtataa ttggcattat aattgtagca ttgaatttaa agtttgcaca
      361 gtcgctgatt ggaaaattta caaagtggat gtcaaacata taaattttag tttattggac
      421 agttcaagga atcagaaatt ggaattttat agtattaata ttttatagta ttaatataat
      481 gtataaaatt ttatagcaat gtatttcata agtataaagt gactagaatt ttaagaaata
      541 tacaaattct ataaaaacta aataatttca agtatatttt aaaaatctta tttttcacaa
      601 gtttaaaatt gtaaacgatt tcatcaagtc tatgaatata cttttaacat gttatagtaa
      661 atctcaatat aaatttacat ttggttcttt gtgtgttatt ttaataataa attaagtgaa
      721 aatgttattt tacattaata tataatatct ttgcataaga gtgaataata taaaagagaa
      781 agaattgata ataaaaactt aacaaaaaaa ttaatacata aaaaaaaata aatataatgt
      841 gttgacattt aattgaaata ttcatacaat aaaattgaaa ataaatattt ccaaatgaga
      901 ttagcgagag agtcctttat acgaaaaggc gccgaagaag aaatttaaga aatgccaatt
      961 tttagagaag ctttcaggca aaaatatcgc taattgatgg gactctggag agacttaagt
     1021 taagatacta taagtcaccg aagaagcaaa ataatattaa attattaaat ctttcaggta
     1081 tacaaacagg gatatatagg ctaggattat tttccatgct gatatatctt ttttttatga
     1141 aaaagtacag gaaataatat caaagttact taaatacagt aggtctaatt ttctagggag
     1201 ggttatatat gaatgaattg aaaagagtat ctttgtacaa tatacacaaa gagcttggag
     1261 caaaacttgt tgaatttgct ggctgggaaa tgcctttaga atatgagggt ataaataaag
     1321 agcatgagaa ggttagaaaa agtgcaggta tatttgatgt atctcatatg ggagaggtac
     1381 agataaaggg agcagagtca gaaaaattta tacaaaacct agttacaaat gatataagca
     1441 cattaaagat aaatgacatt atatatacac ctatgtgtta tgaaaatggt ggagtagttg
     1501 atgatttatt aatatataaa tttggtgaag aagattattt attagtaata aatgcaggta
     1561 atatagataa agatgtagca tggataataa aacaaagtga aggatacaat gtagatataa
     1621 aaaatatatc tagtgaagtg agtcaattag caattcaagg acctaaagca gaagaaattc
     1681 ttcaaaaaat cacagatata gacttaaact caataaaatt ttataagtca attccatcaa
     1741 caaaagtatg tggttgtcct tgtttagttt caagaacagg atatactggg gaagatgggt
     1801 ttgagatata ctgtaaaaat aaatatgtag aaataatttg gaatgaagtt ctaaaggttg
     1861 gaggagaaga tatatgtcca gctggtctag gttgtaggga tactttgaga tttgaagcag
     1921 ctctacctct atatggtcat gaaataaatg aacacatatc tccaattgaa ggtggtttat
     1981 ctatatttgt gaaaacaaat aaagaatcat ttattggtaa atcaatttta tcaaaagaaa
     2041 aagaaagtgg agctaaaaga aagttagtag gatttgaaat gcaaggtaaa ggaatgccta
     2101 gaaatggata tgatataagg attggtgata aaacagttgg atttgtaaca acaggatgtg
     2161 catctccaac gacaggaaaa attttaggta tgggaattat agattctgaa tatgcaaaag
     2221 taggaaatga aataggtata gcaatcagaa aaaaagttgt tcctgctgtg atagttaaga
     2281 aaccttttta taaaaaacaa tataaaaaag ataatattat attaaacaaa gaaaataaat
     2341 tttcatatat acctgctaca agtgaagata aatcaaaaat gttaaaagta gttggattaa
     2401 attcggttga tgaattattt tcagatatac cagaagaagt aaaattaaaa agagatttaa
     2461 atttggaaat tggaaaatct gaattagagg taagcaaaat agtaaaaaga ttgtcagaag
     2521 aaaacttaag tttagaagac ttgacttgtt ttcttggtgc tggtgcatat gaccattata
     2581 taccatcaat tataaaacat ataacttcaa gatctgaatt ttatacagca tacactccat
     2641 atcaagctga aataagtcag ggaactttac aagtagtttt tgaatttcaa tctatgattg
     2701 cagaaattac aggtatggaa attgcaaatg catcaatgta tgatggagca actgctgcaa
     2761 tagaagcatg tataatggca atgaatcaga ctagaaaaag taaaatagta gtgtcaaaaa
     2821 ctattcatca tgaaactttg tcagtattaa gaacttactt acaatataaa gattgtgaga
     2881 tagtagaaat tgacttttgt aatgaatatg ggactacaga tatagaaaaa ttaaaagctt
     2941 ctgtagacaa ggatacagca tgtgttctta tacaaactcc taatttcttt ggaattattg
     3001 aagaaatgga agaaatagaa aagataactc atgaaaataa ggctatgtta attatgagtg
     3061 tagacccaat atcattagga gttttaaaaa caccaggtga gataggtgca gatattgttg
     3121 ttggagaagc tcaatcactt ggaaaccctc ttaattttgg aggtccttat gtaggatttt
     3181 tagctagcaa atctaaatat actagaaaaa tgccaggaag aatagttggg caaagtttag
     3241 atgtagaagg taaaattgca tatgtattaa ctttacaaac tagagaacag catgtaagaa
     3301 gagaaaaagc aacttctaat atatgttcaa atcaagcttt aaatgctctt gtagcttcaa
     3361 tatatatggc tactatgggt aaagaaggat ttaaagaggt tggtatgcag tctatgaaaa
     3421 aagcacatta tacttacaat aagcttgtac aaactggaaa atataagcca atatttaaag
     3481 gtaagttttt caaagaattt gctgtacaag gaaatcttaa tatagaaact ataaatgata
     3541 agctcttaga agaaaatata ttaggtggtt ataatttaga atacaattat ccagaattaa
     3601 aaaattcaac tttgctttgt gtgactgaga aaagaagcaa agaggaaata gataagttag
     3661 ttggaataat ggagggatta taatgaaaga atacaatagt ttgttgatag atatatctaa
     3721 aaaaggtagg aaagcatact cacttccaaa gttagatata gatgatataa aaatagaaga
     3781 tatgattgac caagatatgg caagacaaag tgagttgaat ttgccagaag ttggtgaatt
     3841 agaattagtt agacattata cattattatc aaataaaaac tttggagttg atacaggttt
     3901 ttatcctttg ggttcttgta ctatgaaata taatcctaaa ataaatgaag atatggcagc
     3961 acttccaaac tttactggaa tgcatccata ccaatcttcg gatacagctc aaggttctct
     4021 ttctttgatg tatgatttat caagaagact tgcagaaatt acaggtatgg atgaagttac
     4081 actacagcct tcagcaggtt ctcatggtga gtttacaggg cttatgatta taaaagcata
     4141 tcatgaaaat agaggtgacc ataagagaac taaagtgata attccagatt ctgcacatgg
     4201 aacaaatcca gcaagtgcag ctatggcaaa ctttgatgtg attcaaatag catctgataa
     4261 aaatggagct gtagacataa atgcattaaa agaggttttg aatgatgaag tagcagctct
     4321 tatgcttact aatccaagta ctcttggttt atttgaaaaa aatataaaag aaatagctac
     4381 tcttgtacat gaagcaggag gacttttgta ctatgatggt gcaaacatga atgctattat
     4441 ggggataaca agacctggag atatggggtt tgatgtggtt catcttaatc ttcataagac
     4501 tttttcaact cctcatggag gtggaggtcc aggagctggt cctgttggag ttaaaaaaga
     4561 attagtacct tttttaccaa taccattaat tgaaagaaaa gaagataagt atgtactaaa
     4621 ttatgataga gaaaaatcta ttgggaaaat taaaaatttc tatggtaatt ttggagttct
     4681 tgtaagagct tacacatata tactaactat gggaagggat ggacttaaag aggctagtga
     4741 aatggcagtt ttaaatgcta attatataaa ggaaagtata aaagatgatt atattttgcc
     4801 aatagatacc ttgtgtaagc atgagtttgt attaggtgga ttgccaagag gagaggccaa
     4861 tataaaaact atcgatattg caaaaagact actagattat ggataccatc ctccaacaat
     4921 gtactttcct cttattataa atgaggcact tatgatagaa cctacagaaa gtgagagtat
     4981 agagacatta gatagtttta tagaagctat gaaaagtgtt gctaaagagg caaaggaaga
     5041 accagaacta ttgaaaactg ctccacataa tactttggtc aaaagagtag atgatgcaag
     5101 ggcagtaaag aaacctatac taacatggtc acaaagataa ataattaaaa agtagagatt
     5161 taaagtataa agagaattaa atttgtaaga aaaagctatc taacttaatc cagtttagat
     5221 agcttttttg tatattagta tgtatggtat tttctatata aagttttaaa ttatattagt
     5281 gcttatatag aatattgata tgatgattat gtatagatat taataagaat tgttgaattt
     5341 atcttgcctt aactttattt actcttttat cttaagaaaa acttaactaa aatatagcga
     5401 aattcataaa aatttaggaa atcttaagaa ttataatatt taaatcttta gatttatatt
     5461 ttattatata aactatagaa taataaaata taaaaattga gaattttata atatatttgt
     5521 agatttgagt ataaaaaagt gctaagttga aaggagtaaa atatggataa ggttaattta
     5581 gaaaggtata gttgtgatat aaatgttggt ttaaataaaa atcaacttca aagtagaata
     5641 gatgataatt taattaatgc atttgataat ggaaaaacca aaacatataa acaaattttt
     5701 aaagacaata tatttacact ttttaatctc ataaatattg ttttagtctg tttattagtt
     5761 tcagttggtt cttttaaaaa taccttattt atatttattg ctgtaattaa tactattata
     5821 ggagtaatac aagagataag agctaaaaga ttattggaca atctatctgt tatagtttca
     5881 aataaggtat ctgtcataag agaaaaagag aaaaaagaga ttgatgtaca agaattagta
     5941 ttagatgata ttatgatttt aaaaacaggt aatcaaattt gtgcagattc aaaagtttta
     6001 aatggaaaat tagaggtaaa tgagtctttg gttacaggtg aatctgatat tattataaaa
     6061 aataaagacg attttttata ttctggaagt tttgtagttt ctggagaagc ttttgtaaga
     6121 gttgaaaata taggaaaaga taactatgca aataagatag ttaatgatgc aaagatttct
     6181 aaaaaacata attctcaact tagaaattca ttaaattcaa tattaaaaat tgtaggtata
     6241 ataataattc ctttaggaat tatattgttt gcaaaacagc attttggaaa tggagattct
     6301 atagctacat ctgtagtagg tacagtggca gctgtaaatg gtatgatacc agagggatta
     6361 acattactta cgagcattgc tctagctgta ggaactataa aacttgctag tcataaaact
     6421 ttagtgcaag aactgtactg tgtagagact cttgctagag ttgatacact atgtcttgat
     6481 aagacaggta caattacaga aggtaaaatg caagttgatg atatagtaat gttggaagaa
     6541 gtggatatta atgaaataat ggggaatata tgtaattctc tcaaagatga taatgcaaca
     6601 ctaaatgcaa taagagataa gtataatgtt ttagatacgt ataaagctaa gaatttaata
     6661 ccattttctt cagaaagaaa atacagtggg gttacctttg aaaataaagg tacatattta
     6721 ttaggtgcat ttgagtttat atttaaggaa aaaaataaaa aaattagaat agaagttgaa
     6781 aaatattcta aaaaaggaaa cagagtaata gttttagctc atagtgattc ttatatggaa
     6841 gataataata ttcctgaaga tataaagcca ctagctttta tattgatatt agataaaatt
     6901 agagatgaag ctaaggaaac tttagaattt ttttacaatg aaggtgtaga tataaaaatt
     6961 atatctggtg acaatcctat aacagtaagt gaggtagcta gaaaagcagg tcttaaaacg
     7021 gctagtaatt ttattgatgc aacaacactt aaaaatgata acgatatata cgaagcagtt
     7081 gataaataca gtgtttttgg aagggtaagc ccacaacaga aaaaacaaat gattttagca
     7141 ttaaaaaaac aaaatcatac agtagctatg actggagatg gtgtaaatga tgtgctagcg
     7201 cttaaagaag cagattgcag cattgccatg gcatctggaa gtgatgttac taagaatgtt
     7261 tctaatttag tcttattaga ttcaaacttt gcatcaatgc caaaggttgt tatggaagga
     7321 cgaaaggtaa ttaataacat tcaaagagca tcttctttgt ttttagtaaa gacaattttt
     7381 tcattcttct tgtcactatt aacattattc ttcttcagta gacagtatcc atttgttcct
     7441 atacaattat cactaattgg agctgtaaca gtgggtatac catcattctt cttagctctt
     7501 gaagcaaaca aaagtagaat ttcaggaaac tttttactca atatattaaa aaatgcttta
     7561 ccaggagcac tatgtgtgac agtaaatgta attattgttt acaatatagt tgaatattta
     7621 ggctatagtt caagtgtatt ttctacaatg tgtgctatat taactggtgt atgtggtctt
     7681 ttaatattaa gacaacaatg tttgccattt aataaagaaa gattattttt aattgtaagt
     7741 atgactattg catttgttat tgggattcta tttttaggtg gattattctc atttgtagca
     7801 ttgagtagag aattaattct cataactatg gcattagcaa tattaatgcc aattatgata
     7861 aaagttatgt tatttgtctt ggatgagata ttagagacaa ttgttccaga tttaaattaa
     7921 ttttaaaatg atataaataa gagcagtttt agttgaactg ctctttttag atgtgtttaa
     7981 ttttatataa gaatatgtat ttttattaat cagctatata tgagcaacag tagtcaacaa
     8041 cttcattaac ctttaaatca aaacttgaat cactaggaac attaaatttt tgcccttctt
     8101 tataagttac aaactcattg cttccaggca gttttacatc catacttcca gcaagcatct
     8161 ccattatttc ttcttctcta gtagaaaaag tatattctcc tggcaacatt aatcctaaag
     8221 tttttctttc tccattaggc agtattatta ctctgctact taccttacca tcaaaataaa
     8281 cgtttgcctt ctttactgca gtaacattct taaattcact cattagataa aacctccaaa
     8341 attatttgta catatatatt atataaaaat aatgtaaaaa atgctatata tttgcaaaaa
     8401 aaaatttagt atttattaaa aaaattaata agaataaaaa agagatgaaa ttgcttaaat
     8461 tgataaaaaa tataaaataa attgcaaagt aagcaagaaa agaataagtt gaagagttat
     8521 atattataaa tattaaaaat tttagtatta ataaaaaaga tattacatta atatgaaaat
     8581 ataggaga
//
LOCUS       DAEQJM010000107         8549 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.109, whole genome shotgun sequence.
ACCESSION   DAEQJM010000107 DAEQJM010000000
VERSION     DAEQJM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8549
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.109"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            72..2249
                     /locus_tag="KRQ43_003414"
     CDS             72..2249
                     /locus_tag="KRQ43_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH2743748.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALHSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANVMNIDDDLLKAGYEASIRHMFKKTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDNEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYRESDINSIIDDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            2263..2685
                     /locus_tag="KRQ43_003415"
     CDS             2263..2685
                     /locus_tag="KRQ43_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2743749.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGACPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            3092..3895
                     /locus_tag="KRQ43_003416"
     CDS             3092..3895
                     /locus_tag="KRQ43_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH2743750.1"
                     /translation="MKKLKLIIMLALVLALLITGCSSGNNKNKEEQKTIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMVEPPIQFGAC
                     SFAIQKNEKGEKWTKEINEVIEEMHKDGTLTKISEAWLGKDITKEPINE"
     gene            3888..4556
                     /locus_tag="KRQ43_003417"
     CDS             3888..4556
                     /locus_tag="KRQ43_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH2743751.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMTEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     GKAY"
     gene            4792..5454
                     /locus_tag="KRQ43_003418"
     CDS             4792..5454
                     /locus_tag="KRQ43_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH2743752.1"
                     /translation="MIFNMKYFLELFPIIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMNDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDKGQIEAAYVMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            5514..6311
                     /locus_tag="KRQ43_003419"
     CDS             5514..6311
                     /locus_tag="KRQ43_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH2743753.1"
                     /translation="MVKRNIIKCLVAVLSLTFVVAGCSKKEEVKDEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVAASVNKD
                     NLFEEKVYGDGTNGLQDLDLGRVSAWIDAELTVVGDAKKANMKVRVLDEKLSVTNIAY
                     FFKKNDEKSKTIKEDVNKAIEEMLSDGTVKKISEKWFGMDVSADIQK"
     gene            6444..7619
                     /locus_tag="KRQ43_003420"
     CDS             6444..7619
                     /locus_tag="KRQ43_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2743754.1"
                     /translation="MIETKIKSIALKNREKIIKIRRQIHSNPELAFKEFKTSKLIKEE
                     LNKLKIEYIDVAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSINDNMHA
                     CGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGVDALAT
                     GHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAVYSSIQ
                     QIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKILENIV
                     RNVCRAYGADCKFEKSTGGDAVINDKNMIELGRESACKILGVENVEIIDFPAMTGEDF
                     AIYMKEKPGLFMYIGVGNKEKNINYRLHSNKFNIDEKCLSIASSLFSQLAVDYLCQL"
     gene            7728..8477
                     /locus_tag="KRQ43_003421"
     CDS             7728..8477
                     /locus_tag="KRQ43_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH2743755.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEINQSEVVAILGPSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDIANLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSNKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIVRKEEVFS"
BASE COUNT         3393 a          867 c         1586 g         2703 t
ORIGIN      
        1 atcttattat taaaaatatt cttagaaatt gcactatata aaatataaag tatgatattt
       61 gaataaaaag aatgtataat aagtataata atttgtattt attattggga aaggaaaatg
      121 ttaatatgga tagttataga caacttaaag ctaaaatacc ctgtaaggaa acaggtatag
      181 aaataaagag gactttatgt gatatttgtt ctccaggagt acattgtgga attgatgcat
      241 atgttaaaga tggtaaagta ataaaaatag aaggtacaaa agaacatcca atgaataaag
      301 ggttgttatg taccaaaggt ctttgcaata gagaatatat atatagagaa gatagaataa
      361 aaacacctct aaaaagaatt ggaaaaagag gtgaaggaaa atttaaacca atatcatggg
      421 atgaagctta tagagaaata gcagaaaaat taaatagagt aaaatctgag tatggagcaa
      481 agcatgtagc tttttttacg ggttatggaa agtggtatag accttttttg caaaggtttg
      541 catcttcatt tggttcacct aattatggta cagaatctag ttcatgttca acatcagcac
      601 agatggctgg aaatgttgct actggaagaa actttacaat gcaagatatg gagaatgcaa
      661 aaacttattt agggtgggga tttaatccat actactctaa atttttaaat agtgtgaatc
      721 taataaaatt aaaagaaaaa ggtctaaaat ttataattgt agaccctaga ataacaccga
      781 caactcaaaa actagcagat ttacatttaa gaattaaacc tggaactgat ggagctttag
      841 ctcttggaat ggcgaatcta tttatacaaa aggatttaat agatagagaa tacatagaaa
      901 agcatgtaca tggatttaat gaatataaag aatatgtaaa attatttgat ttagatactg
      961 taagtagaat tacaggagtt tctaaagata atatagtaaa agctgttgag atgttgtcac
     1021 aaggtccatt ttgtataaat gaaagtgcag ctccaatagt tcatcatcaa aatggatttc
     1081 aaaactatag agcaatgatg tctttatctg ctataacagg taattatgat agaataggtg
     1141 gaaacatacc aaaacaagat tactttgctg gtaagatagg tggattccaa acactagaaa
     1201 aagagtttgt aaaagaagtt ctacctaaaa atataaatga aagaattggt ggagaaagat
     1261 ttcctctatg gaatgaaatg gtaactcaat ttcaagctat ggatttacct aggcaaatag
     1321 aagaaaagac accatatgaa ataagagctt tgttttgtca tgggataaat gctagaatgt
     1381 ttcctaattc agggagactt tttaaagcgt tgcatagtgt agattttttt gtgaatatag
     1441 atttatttat gacagataca tcaaaatatg cagatatact tttacctgcg tgtacatcat
     1501 ttgagagaga agaatgtaag agttacccag gagggtatat tacatatacc aaaaaagtta
     1561 ttgataaatt atacgattca aaatcagatg tagaaatact ttcagattta gcaaatgtta
     1621 tgaatataga tgatgattta ttaaaagcag gttatgaagc aagtataaga catatgttta
     1681 aaaagacgtg tgtagatgta gataaactta aagaaagtga tttaccatta aaatgtaaag
     1741 attttaagcc atatatagta ggctcatata caagagaggg gtatgatact agcacttcta
     1801 ggtttgaatt aaaatctaca attattgaaa aatataaaga ttttggactg gatgcactac
     1861 caacatatag aggatttaat gataatatag ataatgaata tactcattta ttgacatcag
     1921 gagcaagaat ttcaaatgca ctacattcaa gacttcatga catcaaactt tcaagaatat
     1981 taaaaaatga agctagttgt gatatttcca gcttggatgc aaaagaattg ggtgttatca
     2041 gtggagatta tataaaaata actactaaga taggaagttt ggatgtaaaa gtcaatgtta
     2101 ctgatagagt cttatataag aatatacata tgtatcatgg atatagagaa tctgatataa
     2161 atagtattat tgatgataat tttgaccctt atagtggatt ccctgcgtat agaagttgca
     2221 agtgtaagat tgaaaaaatg aatagataaa tggagagata taatgaaaag tttatttaaa
     2281 tttaataaag aattatgtac agcatgtgga gcatgtttgc ttgcatgtat agaccaaaat
     2341 gataataata tagacaatgg tgaacttttt agacatgtat ttacaataga ggaaggtgaa
     2401 aatatagaat atttttcatt agcatgtatc cattgtaatg agccaaaatg tttaggtgca
     2461 tgtcctaaaa attgttttaa aaaagaagaa ggattcgttg tattagacaa tcaaaactgt
     2521 atagggtgta aactttgtga aaaagcttgt gaatatggag ccttaattta tggaaatgat
     2581 ggtaaggcaa ataagtgtaa tggttgtatt gagagatata agtgtggtat ggattcacct
     2641 tgtgtaatgg tatgtcctac aggagcatta aaatttaata aataaattaa atatagagag
     2701 tgacttatac ttggtataag atatttttac aaaaagctat attgagtttg ttataataaa
     2761 aactcaatat agctttttta tggatatagt tggatactat aatgtgattt ttagtaatag
     2821 ttttttgcta ttggacaaag actgtaaaac atattaaact tatgttgttc aaagtcgaag
     2881 tataatataa taactagaaa attgatttat agtgttataa aagcaaattt agtaaggtat
     2941 aaaataagag gcaatctttt actacagtat caatatttgg gagttatgtt atggcagagc
     3001 cattaaacaa ttataatggt acaagtgatt caacctttga aaatgtatta tataaaaaat
     3061 taaaataaga ttaaaaagga gagaataaat tatgaaaaaa cttaaattaa ttattatgct
     3121 tgccttggta ttagcacttt taattacagg atgttcatca ggaaataata aaaataaaga
     3181 agaacaaaaa actataagag ttgcaacatc aggaacatat tacccttttg cttttaaaga
     3241 taaagataaa cttaaaggat ttgaagtaga tttttgggat gaatttgcta aacgaactaa
     3301 ttgtaaagtt gaatgggtat taactgattt tagtggatta tttggattat tagaagctga
     3361 taaagcagat gttgtatctg ctcaacttac tgcaacacct gaaagagaga aaaaatatgc
     3421 tttttcagat gcttataatt atagtggaac aaacattatt gttagagaag atgatactag
     3481 tataaaatca atagatgatt tagttggcaa gaaagtaggt gtgggtactg gagcagtagc
     3541 aaatgaaata ctaaaagaaa agtacccaaa tgatgaaata aaaatagtaa attattcaag
     3601 tgcaactctt aaagggaatt atcaagatct agaaatggga agattagatg cagtagttgc
     3661 gcaggatgtt gaggctttaa tagctataaa agaacaaaaa ttaaatctta aaatggtaga
     3721 acctccaatt caattcggag cctgttcttt tgcgattcaa aaaaatgaaa aaggtgaaaa
     3781 atggacaaaa gaaattaacg aagtaattga agagatgcat aaagatggga ctttgactaa
     3841 aatatctgaa gcctggctag gaaaagacat tactaaggag cctattaatg agtaatttta
     3901 attttgaatt ttgtctaagt atatttccat ttttgattaa agcattggga ataacaatac
     3961 taatatctat tgttgcattt tttttatcaa tattattagg tgtaatactt gcctttttca
     4021 cacagacaaa atcaaaagtt ttgcaataca taacaagagt gtatgtttca ttctttagag
     4081 gaacaccact tttaattcaa atatttttct tttactttgg atttccaatg atattttctt
     4141 ttatgaaaga ttgttcacct tatttagcaa tagtaatttg tttaggtgta aattcatctg
     4201 catatatgac tgaaattata cgagcatcta ttgagagtgt tgataaagga caacaggaag
     4261 catgttatgc ttttgggtta agtaaatatc agtcaatggt taaaataatt ctacctcaag
     4321 cagctacatc tgcagtacct cctattgtaa gctgtacact ggacataatt aaaggttctt
     4381 ctttaggtct aactatagga atacaagatt taatgggagt agctcaagta gaggctgctt
     4441 caagttttaa atattttgag atatatatga taacgatatt aatttactgg gcagtatcta
     4501 taatattgag taatatacaa agcaaagttg aaaaaagaat aggaaaggca tattagattt
     4561 caatatttaa aaatgggatg atgtagatat attattactt gtaaataaat ttttaatttt
     4621 agaaaaataa acttagtaat ctaaattatt gagaaaatat agtatcaaaa tggactgtat
     4681 aatcaagtta aaaaatagtt tttctattga aaaaataaat aaaattctat tgtaatttaa
     4741 tattcgacaa agttttataa aaaacaacat taagctaggg ggacttattt tatgattttt
     4801 aatatgaaat attttttaga attatttcca ataataatga aatcgttcaa tgtaactgta
     4861 attttggcaa taagttcatt agtattttca ttaattatag gtacaatagt agcattatca
     4921 tcttattaca aagtgaaagt attgaatcaa atatgtaaag tatatgtatc tatctttaga
     4981 ggtacgcctc ttatgccaca gttattcttt ttatattttg gactagcgta tatgaacgat
     5041 tttgttaaaa atatggaccc agtatttgca acatctatag tacttagttt aaatatggga
     5101 gcttatatgt ccgaaacgat aagggcatct atactttcaa ttgataaagg tcagatagaa
     5161 gcagcatatg taatgggatt aacaaattta caaacaatga aaaggatagt gataccacag
     5221 gccgtaagag ttgcactgcc atcattattc aataatttta tagatttaat taaagggtct
     5281 tctgtagctt ttgttgttgg agtaaatgat ataatgggtg ctgccaaatc acaaggagcg
     5341 ttgagtttta agttctttga agtgtatgga gcagttatgg taatttactg gtgcataata
     5401 actcctttag ggtgggggca aaaaaaatta gaaaagaaaa taagcaatta ttaagttatt
     5461 aagaaaatac ataaaagtat ttttatataa aaaatggtgt gaggagaaga gatatggtaa
     5521 aaagaaatat tataaaatgt ttagtggcag ttttatcgtt aacatttgta gttgctggtt
     5581 gttcaaaaaa agaggaagta aaggatgaaa aagttataac tgtagcttca tctaattcag
     5641 ctgacccata ttcttatgtt gataatggtg agcataaggg ttttgaagtt gatatgtgga
     5701 aagagattgg taaaagaagt ggatataaga taaaaatgga accaacaggt tttagttcta
     5761 tatttgggat gttagattct ggtaaagttg atgtggcagc caatttcttt ggaatgtcta
     5821 aagaaagatt agaaaaatac gatgcttcta taccttatgg ttctgattct gtatgtatag
     5881 ctgtaaaaga tggaaacaac gaaattaata aacttgaaga tttaaaagga aaagttgtag
     5941 cagtttcaga aggttctcaa gggcaacagg ttgcagctag tgttaataaa gataatttgt
     6001 ttgaagaaaa ggtttatggt gatggaacta atggtcttca agatttagat ttaggaagag
     6061 ttagcgcatg gattgatgca gaacttactg ttgtaggaga cgctaaaaaa gctaatatga
     6121 aggtaagagt attagatgaa aaattatcag ttactaatat agcatacttc tttaagaaaa
     6181 atgatgaaaa atctaaaact ataaaagaag atgtaaataa agcaatagaa gaaatgcttt
     6241 cagatggaac agtgaaaaaa atatctgaaa aatggtttgg aatggatgta agtgctgata
     6301 tacaaaaata aatactttaa aattaaaata taaaactgtg ataactatag ataagtatac
     6361 taaatttatc tatagttatc tgtgtattac aatgtattta gattagtctt tataaattaa
     6421 aatgagttat ggaggtcttg caaatgattg aaactaaaat aaaatccatt gcactaaaaa
     6481 atagagaaaa aatcataaaa ataagacgac agatacacag taatccagag ttagcattta
     6541 aagaatttaa aacatccaaa cttataaaag aagagttaaa taaacttaaa atagaataca
     6601 tagatgttgc tggtacagga gtattagcta ctataaaagg aaaaaataat ggtgggaaaa
     6661 ctatattgct tagagcggat atggatgccc ttccaatcaa agaggaaaat gatttagaat
     6721 ttaaatcaat aaatgataat atgcatgctt gtgggcatga tgcccatgtt tcatggttgt
     6781 taggaacagc aatgatttta aatgacataa aagaagaatt gaatggaaat gtaaaattac
     6841 tatttcaacc tggcgaagaa aaaggtggtt ctgatattgt aattaaagaa aatgtacttg
     6901 aaggtgtgga tgcattagca actggtcatt gttggccaac tattgaatca ggaaaaattg
     6961 gaatcgctag aaattgtgct atggcagcga ctaatacttt tgaaataaca ataattggca
     7021 agggcgggca tggagcagag cctcataatt gtatagaccc aattgcagtt ggaaatgcag
     7081 tatattcatc cattcaacag atagtttcaa gaaaaattga cccagttgta cctgtagtag
     7141 tgtctgtttg ttcttttaat tctggtgttt ctaaaaatat aataccagat gtatgcacac
     7201 ttcaagggac tattagagcg ataagcaagg aacaagtaat tgaagtaagt aaaattctag
     7261 aaaatatagt aagaaatgta tgtagagcat acggagcaga ttgcaaattt gaaaagagta
     7321 caggaggaga tgctgttata aatgacaaaa acatgataga gctaggaaga gaaagtgctt
     7381 gcaaaatact tggagttgaa aatgttgaaa taattgattt tcctgcaatg acaggtgagg
     7441 attttgctat ttatatgaaa gaaaaacctg gtttatttat gtatataggt gtaggaaata
     7501 aagaaaaaaa tataaactac agattgcata gtaacaagtt taatatagat gaaaaatgtc
     7561 ttagtatagc atcttcatta ttctcacaac ttgcagtaga ttatttatgt caactataga
     7621 gtacattcat aaaaatatat ttagcctatt tttaaattta atgctagtat attaattttg
     7681 atgtagaaca tattatttat tatatttatt taaaaaggtg gataacaatg ataaaagtag
     7741 aaaatttaca taaaagtttt aaagggacag aagttcttaa aggtataaat ttagagataa
     7801 atcaaagtga agtagtagct atacttggac catctggaac aggtaaatct acgttactta
     7861 gatgtttaaa ttatttagtt gagcctacaa aaggaaagat aatgattggt gatgtaaaag
     7921 tagatgtaga aaaagcaaca aaaaaagata tagccaattt aagaaaacat acatctatgg
     7981 tatttcaaaa ttataactta tttaaaaata aaacagcatt agaaaatgta atggaggcat
     8041 tgatagtagt acataaaaag agtaataaag aagctagaga aatatcttta aaattaatag
     8101 ataaagtagg tatgttggat aggaaagatt tttatccatc aaaattgtct ggggggcagc
     8161 aacaaaggat aggtatagca agagcgatgg cagtaaatcc aaatgtaata ttatttgatg
     8221 agccaacatc tgcacttgac ccagaacttg ttggagaagt tttaagcgtt ataaaatcgc
     8281 ttgcgaaaga aggaataaca atgcttattg taactcacga aataaatttt gcaaaagaag
     8341 ttgctgataa aattatattt atggataatg gtgtaatagc tgaagaagga actcctgatg
     8401 aaatatttaa taatcctaaa aatgaaagaa ctgcaaaatt tttaaatatc gttaggaaag
     8461 aagaagtatt tagttaaaag tgtataaatt aagtattaga agatatgtaa gatactccca
     8521 ttaaatttat aagttagata ataaattta
//
LOCUS       DAEQJM010000108         8541 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.110, whole genome shotgun sequence.
ACCESSION   DAEQJM010000108 DAEQJM010000000
VERSION     DAEQJM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8541
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.110"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            78..308
                     /locus_tag="KRQ43_003422"
     CDS             78..308
                     /locus_tag="KRQ43_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HBH2743756.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            321..470
                     /locus_tag="KRQ43_003423"
     CDS             321..470
                     /locus_tag="KRQ43_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HBH2743757.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            727..1164
                     /locus_tag="KRQ43_003424"
     CDS             727..1164
                     /locus_tag="KRQ43_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBH2743758.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            1421..2314
                     /locus_tag="KRQ43_003425"
     CDS             1421..2314
                     /locus_tag="KRQ43_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH2743759.1"
                     /translation="MQLYNTPFNTNKHLIYFFTSTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            2492..3316
                     /locus_tag="KRQ43_003426"
     CDS             2492..3316
                     /locus_tag="KRQ43_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2743760.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKHEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREVVPDYQSEGILWEKLSKFIKEEHIE
                     VSRQPNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            3415..4023
                     /locus_tag="KRQ43_003427"
     CDS             3415..4023
                     /locus_tag="KRQ43_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2743761.1"
                     /translation="MEKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNVEQRNGLIDFQLDLLLVDITK"
     gene            4127..4303
                     /locus_tag="KRQ43_003428"
     CDS             4127..4303
                     /locus_tag="KRQ43_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743762.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            5599..6351
                     /locus_tag="KRQ43_003429"
     CDS             5599..6351
                     /locus_tag="KRQ43_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743763.1"
                     /translation="MLKVNQLCKSYKTGNKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            6341..8452
                     /locus_tag="KRQ43_003430"
     CDS             6341..8452
                     /locus_tag="KRQ43_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743764.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYI
                     VPSLTINKLNYRLPSVWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVAGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIERVYMKKSSYDMFFNSK
                     DFSKLIDKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
BASE COUNT         3228 a         1096 c         1125 g         3092 t
ORIGIN      
        1 actaatattg acaattaaaa taccaatatt aacaagcaaa caattaaaat ataaattatt
       61 atatcggagg taattatatg gaaattaaga aaaaattagt catgagcttt aaaaatgtaa
      121 aggataaaca agtttctttt tctatagaaa atccaaagga tgatttaact gaagaaaata
      181 taaaatctgt catggatttg atagtatcta aaaatatttt ttcggttgga ggatttgacc
      241 tagcttctgt tgttgaagcc aaggttgtgg aaacaaatac cactccttat gacttagtta
      301 tagaataggg ggctaatttt atggatgata gtttacaact gttaataacc aatgttggtt
      361 ttcctatagc tctatccatg tacttgttgg ttagaattga gggtaaatta aatactttat
      421 caaacagtat tgatacatta tccaaaaata ttttgatatt taagaagtaa tttgacaata
      481 tatgtaagtc ataaaatagg tctatttgta aaataattag acatattcta tgctaaatac
      541 taggatattt ggataattta tccaaatatc catagtattt ttttgaattt taccacctca
      601 aatttgaatt tcactatttt atttttgaat ttcactatgc ttaatttgaa atttagaacg
      661 catctagttg gactcaataa gatataatgc tattctaatg acagtaataa aatgaggtga
      721 tgattaatga aaatacatgt cgaacaaggt attaattgtg atgatattga aataaccata
      781 aaatgttctg ctctagataa taacattgaa aaaataattt cattattgag tacaccatta
      841 cttgatataa aaggtaaaaa atcaggagag atttataaac tcaatgtctg tgatatttta
      901 tactttgaaa cagttggaaa taaaacattt gcttattatg aagatgatgt atttgaaatt
      961 gatttaaaaa tatataaatt atcaaaatta ttagctaata catccttctc acgaatatct
     1021 aaatccatga ttttaaatat ggactacata aaaagtataa aagtaatatc acataatcgc
     1081 atgcaagcta ctttaaaaaa caacgaaaaa gttattataa atcgtcgtta tataaaaaat
     1141 attaaagaaa agctaaacat ttaataaaaa tctaaagtaa tttattaata tcactaattg
     1201 caaatttatt gacctattta ataattaata ataatataat atgttcaata ttaaatacta
     1261 attaattata tttagtgtaa aaataattaa tcaaaatata aaaaatagga tattattata
     1321 ggcaataact aacatcaaac gataacttaa tacatataaa aataaataaa caattaataa
     1381 aaattaaaac ttcattataa aacggaagga tagtgaaaaa atgcaactat ataacacccc
     1441 ctttaataca aacaaacact taatctattt ctttacatct acgctagtat tgaactggat
     1501 attcagtctt acacctgcgt tgctcggaat tacaaataca atacttggag aaatcatttt
     1561 ttatcttgca tatacatcac cagctattgt aggtctattt tttatttcta caatctatcc
     1621 acaaagtgca aaacaagatt ttatttatag atacctaagc tttaaagaaa ttagaataaa
     1681 atggatacta ttaacaatat tattttttgc tttaactttt attacttcgt taataatcgg
     1741 aaattacttt aatgtaaaaa cttctgatat agattggata cacatagcag tgtttagacc
     1801 ttctaaaata gcttatatgc tattagcaag ttttatattg agtatactta gtcaagaagc
     1861 tggatggaga ggatacgcca ttgacaaatt attagttaga tttggattta taggctcttc
     1921 aattatttta gggcttgttt gtggaatctg gtatctaggg tcgtatttta cacctaatca
     1981 aataccatat aatttggcac aatactccct atttgatgct tttttattta taccaaacat
     2041 tgtactttta aactttataa ttaattttgt atatatcaat acaagtagaa gcattttatc
     2101 agctgggtta gttcatatga tgtactattt tttcaacatt caattacttc tacactaccc
     2161 tattaaatta tgtgtaatag ctcaatatgt acaaataata tttggtttaa tatttcttgt
     2221 atatatgatt tcttctaata aatttaaaca gaaggtaaat tctgaaattg aacagataaa
     2281 gtcggatgat tttgaatttg agttagactg gtaattttaa tatgaattat aaattaagat
     2341 aatctatgat ttgatacgat tactacttaa atataattta ctctctataa tttattgcaa
     2401 catctggaaa ataattgtat ttccacaatc gcttgaagta tataaaaaca aaatatatac
     2461 taattataag tgaaaaggag gtcatatttt catgtttaaa ataggagagg tttcaaaact
     2521 aacacaaatt tctattcgta tgttgcgtta ttatgatgaa cttggtattt taaagcctgc
     2581 agaaatagac aaatatacag gtcatagatt atactcagtt gaacagattt caatattaca
     2641 aagaattgta ttattgagag attcaaaatt tagcgttgca gaaatagcaa atatcgtaca
     2701 taattggaat gatgaatttg taattaaaga attgaataga aaaaagaatg aaatacaaaa
     2761 ggaaataaag cacgaacaac aaagaataaa taaaattgat aaatttatag aagctataaa
     2821 ctgtgataaa gatgaaattc attacaatgt tgtctttaaa aagattccaa gttataaaat
     2881 catatcactt agagaggtag tcccagacta ccaatctgaa ggtatactct gggaaaagtt
     2941 atctaaattt attaaagaag aacatataga agtatcacgt caacccaaca ataatatagc
     3001 tttttaccat gatgaagaag tcaaagataa tggtgtagat attgaagttg gaatggttgt
     3061 aaagaagatt ggaaagaaca aatctggatt tatatatcgt gagacagaag aaattgatat
     3121 gatggcatgt actatggttt atggtccata tgaaaatata gctggtgcat atgaatcgtt
     3181 ctgttattgg ttagataaaa atagtgatta tcaaatatca ggtataaata gacaaatcgg
     3241 tcataagggt gagcataatg aaataaatcc tgaaaattat cttacagaaa ttcaaatccc
     3301 ccttataaaa gtctaatcga ttagtactta aatacttaag tactaatcac ccattgacat
     3361 cccaaaattt tcatgatagt atctaaacgt gtattaaaca tgtttaattt ttttatggag
     3421 aaacttttaa ggggaaaaat tatgaaagca gattcaacaa aggaacaatt aattaatgcc
     3481 acaatccagt tactatcttc acatagagat gtttcaagca ttacggctag agaaattgta
     3541 gctaaagcaa atgtcaattt agctatgatt aattattatt ttaaatctaa agaggagtta
     3601 attaatattt ctattaaaaa atttttaaag cgtcatatgg atgaatataa ggctacacat
     3661 gatactaaaa atttagcacc taaacagcaa ttaagggaaa tactaattgc attttttgat
     3721 tttataggtg aacatagcca atttataaag atttctgtac cctatatatt gatacaagaa
     3781 gaaattgttt atccatttga gatactacct ttaattaagg ctcactatga aaatcagaat
     3841 aacaaaaaaa ctgaagctga atacagaact attgcgtatc aaataacttc atttattcag
     3901 ttgctttttc ttcgttctaa tgcttttttc aagtatagtg gtattgatat tcttaatgtt
     3961 gaacagagaa atggtttaat agattttcaa ttagatttat tattggtaga tattacaaaa
     4021 taatactata ttaatttttt atgtacattt ttttatttta tggtaacgtt tgaaaatatt
     4081 ctcattgact aaaaatactt gcattaaata agggggagga attttaatgt tttttacatt
     4141 tataggagta atatcagcaa ttttattgtt gtgtacaatt atatgtggtt tatggataaa
     4201 acttaataat cgtaataatg actctaattc tcactttact ttttcaatac tttcaattgc
     4261 tttttcactg ttaattgtgg tggccttttt agtaagaaat taatgtcttt gttatgctgg
     4321 ggtttattat tatagatttt tattattgca tgatttttac tatattatag tatttttatt
     4381 atattacagg gtcttattta ttatagtgtt ttgttattac agcattttat tatattacag
     4441 agtcctattt attataggat ttttattata ttgtaaaatc ttatttatta taggattttg
     4501 ttatattaca gacttttatt atattacaat ctcttattta ttgcagtgtt ttgttattac
     4561 agtatttcta ttatattgca aactcttatt tattatggtg ttttgttatt gcaacatttc
     4621 tattatatta taaagtctta tttattacag ttctttgtta tactacagac ttttattatt
     4681 acagcatttc tattacaatc tcttatttat tacagttctt tgctatacta cagaccttta
     4741 ttattgcaac atttctatta cattgcaaag tcttatttat tacagttctt tattatacta
     4801 cagactttta ttattacaac atttctatta tattacaatc tcttatttat tacagttctt
     4861 tattatacta cagactttta ttattacagc atttctatta cattgcaaag tcttatttat
     4921 tacagttctt tattatacta caaaccttta ttattacaac attttattat tttaacgtct
     4981 ttactataat atagtaatat tttaatatct caaaatcata tcaatcactt ttcagcatag
     5041 tctaaaatac ttccactttc taaaattatc tatcatacct atactaataa tactttttaa
     5101 cctttttatt atacatttca attgttttta acgacctatt tatttccaaa actccaatat
     5161 attttctcaa ttacattgtg ttaataaccc ctaaatcctt tcaaattatt tacaatacat
     5221 tccattaaat aatcttactg ctctataatt ctttttttct ttttaaccct actatacatt
     5281 atttacatca tttttttcaa tacaacattc gttattctat aaccttttta cttttactat
     5341 ataccttttt tctaactaca ccttcaatgt tccacatcat attactttag cacaacaatt
     5401 aatacctaaa aataaccctc taaatcctcc aataatataa tcaatttaac tataataata
     5461 acctctcaca ctatccaaac aatatatttt caaacattac aaaaaaacat ccaactatta
     5521 caatattgct catatccctc ctcccctttc aaatgctatc attgacttac aagataaatg
     5581 aaagtgagga tgatatatat gcttaaagta aaccaattat gtaaatcata taaaacaggc
     5641 aataaaacat atcctgtatt aaaaaatatt tcttttgaaa tcaacaaagg agagtttgtc
     5701 gcaatcatgg gttcatcagg aagtggaaaa actactcttt taaattgtat ttcatgtttt
     5761 atcccaattg ataatgggga aataattctt ggaaataata atataagaaa tttaaaagaa
     5821 aaggaacttt cagaagttag aaaccaacaa ctaggatttg tattccaaga tttcatgcta
     5881 tttgatggtc ttagtgtctt tgaaaatata tgtgttccac aaattatcaa aggtagtcaa
     5941 gtcttacaaa tggaaaaccg tgcaattaat ctatgcgagc tatttggtat tgaacatatc
     6001 agaaaaaaat accctgccga aatatctggt ggagaaaaac agcgtacagc agtagcaaga
     6061 gcactcatga acaacccaga tttaatatta gcagatgaac caactggtaa ccttgatagt
     6121 aagtcttgtc gtacagtcat tgaatcattt ttaaaagcaa agcaagaatt agatgctact
     6181 atactcatgg ttacacacga tagctttgca gcaagcttct gcgaccgagt tattgtgctt
     6241 aaagatggaa taatttataa agaagttgta aaatcaaatt caagacataa attcctagat
     6301 gaattactag aagttttaaa agaaatggga ggcgctcaag atgacaatta ataaattata
     6361 cagcaaactt cgagcctata attggaagaa ctatacaact ttattctttt gtataatact
     6421 ttctgtggta ttagtaactt catatgctct aatttatttt agcccaacaa tacaaaacat
     6481 acttccaact ggtggagata gcagaaaaca ggctacaatg atattctcag ttgctatatt
     6541 aggatgcgct gtctttacta catacgcttc ttccctcttt ttaaaattta aaagcaagga
     6601 aattggtatt ttcatggctc taggaacaga taagaagaaa ttaaaaaaac ttctattttc
     6661 agagatattg ttaatttcaa tagtatgctg ttttttaggt cttatattaa gtattcctgt
     6721 atcttttggt atatggaaaa tatttcaatt agtgattatt gataccagag aaatgacata
     6781 tcattttgga actcaaggat tcatatatgg atttatattt agtgtatttg tgacattatg
     6841 catatttata ctttctgtaa aatttattaa tcgtacaaat ataattgata tattaaatga
     6901 ccagagaata tctgaaccaa tacaggatgt aaaggactgg tatggtatat taggtataat
     6961 ttttattata ctaggtattt ttctaggata tatcgtacct tcactaacta taaacaaatt
     7021 aaattataga ctaccatctg tatggagctt tacttatcta ctctctctta ttggaatata
     7081 tatgattatg acatacatag ttgtacatgc taaaagagga aaacatccag aaaaatacta
     7141 taaaaacatc atatcaacta gcatgatgag atttatggga agacaaacag taaaaaacat
     7201 gtgtgttatt tcatttttga ttgcaggagc attatttgct gtattctatg ttcctaatat
     7261 ggttgcaggt atctatgata ctcttaaaaa taaccctata gattatactt ttacctacaa
     7321 tcaaagagat aaacaggtat caaaaaaaga tattgaacaa ttagcagata aacacaatat
     7381 aaaaattcaa aactatatgg aaattccttc tatagaatta attgttgatg gtgtagaatc
     7441 aatatatcat aaagatggaa ctatcgaaag ggtatatatg aaaaaaagct cctatgatat
     7501 gttctttaat tctaaagatt tttccaagct aattgacaaa ccaataacta taaaaaatgg
     7561 tgaatatctt gctgttgtaa ataaaggaaa tgaaaatcaa gattataaat ataccaaatt
     7621 tatatcaagc ccagtcacag aaaaagaaat cccctttaga tatgctggaa aaataatatt
     7681 taatggttct ttttttcaaa atagaagtat gaacgcctat gtccttaatg atgaggatta
     7741 taaatcattt actaaagatt tatccataaa aaattacaat aattctatac tatttaatgt
     7801 agataaagat acctatgctt ttgccaatga cttaaagaaa gaaattataa aaagaacatc
     7861 taaggaaatg ggcatgttca gtggttatga tgaatacgta aaaaaacgtt atgaatcaac
     7921 tggaagaaaa tattttatgg atgaagaata tccaagtggt gaaggtcatt taaaactaga
     7981 cccaaacaac aatcagttgt atcttaattg gaaatactat cctaacttta aaattttaca
     8041 aagccaagat atgataaaaa acatggcagt cttcttaatg ttattcatat atgtggcaat
     8101 catatgtttt acagcagtag gaatcattgc atatacaagg ggtgttacta tagctataaa
     8161 tcacaagcag gtctttatgg atttaaatcg attaggagca aacaatgatt atataaagtt
     8221 ctgtattaga aatcaattaa agaaagtatt ttcataccct cttattgcag gaagtttttt
     8281 aatttatctg tttaatttta tgattatgtt aaataatgat ggtagaatcg tcaatagtga
     8341 ggtcaatgct cttttgataa acttaggttt tatagggatt tgtggagttt atatgtacct
     8401 tatatatcta ttaacttata agaaattcaa aaaaattatt ggtattttat aataaggaag
     8461 gttgttagat ttttaaagta ataaaatcat tactttttat aataagaaaa gcattagcat
     8521 tttaaattaa aaaaggttat t
//
LOCUS       DAEQJM010000109         8365 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.111, whole genome shotgun sequence.
ACCESSION   DAEQJM010000109 DAEQJM010000000
VERSION     DAEQJM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8365
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.111"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            343..1053
                     /locus_tag="KRQ43_003431"
     CDS             343..1053
                     /locus_tag="KRQ43_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743765.1"
                     /translation="MISIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSSGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            1047..2363
                     /locus_tag="KRQ43_003432"
     CDS             1047..2363
                     /locus_tag="KRQ43_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH2743766.1"
                     /translation="MLTNLSIGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIFIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMI
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYIDNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIENND
                     ICSIFANSLDNAIEACMDINNELEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            2375..2515
                     /locus_tag="KRQ43_003433"
     CDS             2375..2515
                     /locus_tag="KRQ43_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBH2743767.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            2574..3155
                     /locus_tag="KRQ43_003434"
     CDS             2574..3155
                     /locus_tag="KRQ43_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBH2743768.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNISVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNNDQ"
     gene            3232..5010
                     /locus_tag="KRQ43_003435"
     CDS             3232..5010
                     /locus_tag="KRQ43_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743769.1"
                     /translation="MNLLNIVESIVSCIKGLARRGINMSSIKVISDFITKIIRKNILF
                     AITVIIINYHLIQRWTHISNRGISFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTV
                     KILCRNNFDYFLGISVAVTRNNFIFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILVFE
                     WFLPLTILSIVISFISVIINNLILKITLSSVFLYLTSTKMLDRVIDIKEPFFKALFKS
                     LNIFEDQSYAYYSDFVGKVNNSAYVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLI
                     VIVVYSILFIGLNYISIDMSTYRDEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNI
                     KDRIVLLNTSNEELTNINMILDEIFDIKYIKVNSENIKFNKKKDLIEVNLKESLEPND
                     EVTLDIEYEGYINVLTSWNQNKYIATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSK
                     NNVYSNLPLLNKTSNFLKKDYIFEGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMD
                     IEEKIKFLIETRNEILGDSKASVDAKKYVDEVDNVMESIKRKKINMILVADLPSNEFL
                     YEDSKGEKISITIYHWLSGNILIIDK"
     gene            5025..5897
                     /locus_tag="KRQ43_003436"
     CDS             5025..5897
                     /locus_tag="KRQ43_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2743770.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYIPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINNKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            5898..6686
                     /locus_tag="KRQ43_003437"
     CDS             5898..6686
                     /locus_tag="KRQ43_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743771.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYLGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(6782..7615)
                     /locus_tag="KRQ43_003438"
     CDS             complement(6782..7615)
                     /locus_tag="KRQ43_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HBH2743772.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPLGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDKRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(7683..8312)
                     /locus_tag="KRQ43_003439"
     CDS             complement(7683..8312)
                     /locus_tag="KRQ43_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBH2743773.1"
                     /translation="MDENITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMI
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
BASE COUNT         3385 a          807 c         1174 g         2999 t
ORIGIN      
        1 tgaatattta aaatatagtg tgtattcttc aaaattatag cgataattaa aatattacta
       61 taaaaaggaa ggtgcatact ttttgtttaa caaaaactag atactaaaaa cttctcgaag
      121 aatatgttat taaaatcgct aaatatattc aatatatatt aaaaaattgt attataatga
      181 aaattaaaat agattgtaaa tccaaaaagt aatacttaat gtccaaaaag ctaaaattaa
      241 aatctaaata gctatttgct acagaagtat gttaaaatat gtaaaatgaa tagaaatttt
      301 atatatttat taaaaatata taagaaagga tgtttaagaa ttgtgattag tataggaata
      361 tgtgatgatg aactacatta tcgaataaaa ataaaagata tattaagtga aatattaagt
      421 tcatatccta taaattataa catatatgaa ttttcatcag gagaagagtt actaaataac
      481 tatcctaaag atttagacat attaattatg gacatacaaa tgaaaacaat aaatggtatg
      541 gatactgcta ggaagataag agagtttgat cataagttag aaataatatt tgttacttca
      601 tttgtagagt ttatgcaaga aggttatgag gtaaaagcat acagatatat actaaagcca
      661 ataaataaag aaaaaatttc taaaagtgta ttaccttgta taaatgagat gatgaaaaag
      721 agaaataatt acttaactat aaatgtaaaa aattatgtag accgaattaa aatagattct
      781 attacttata tagaaacaga tagaccgaat atattgattt atacacatga tgatatgtat
      841 attactaaaa tgagtatatc taaaatagaa aagatattaa atgaatatgg attttttaga
      901 tgtcataata gctatatagt taatttaaaa ttagtagaat caatgagtgg aagtactgtt
      961 atagtagatg gcaaaagtat tccaataagt aaatatagag ttaaaggctt gaaacttgct
     1021 ataactaata tattagggga tatagtatgc taacaaatct aagtatagga ttttggaata
     1081 ttattaattt agtttcaggt actatagatt ggattatatt ttttttagta atccacttag
     1141 ttggaaagag gaaaatatct aatataagat atatatttac aacaataatt atatttatat
     1201 ttatggcata cataaatgta gttaaagtgt ttccaaatat taagattctt ctatgtatgg
     1261 taataggaat atcattttat ataacatcat atgaagataa aatatataaa agtataatag
     1321 ttagtttatt gttttggcta ggattaatga ttgctgaagg ttctgcagta ggtctagtag
     1381 tatttataaa taaattaaat aatattaaca taacacaaca tgaaaactta tttagaatac
     1441 aagctattat tatgtcaaag gtatttttat ttataggttt tatattgttt aagtatttta
     1501 aattatcttt agattttaaa cctaaagata tgatactaat aggaatacct atattatcta
     1561 atatagttag cttattactt atatttgaat ataatttaag agtcaataca attactacag
     1621 aaaacttatt tatatttata tttgcaattt tattgatttt atcatcaagt ataatacttt
     1681 taatagtaat agggaaaatt gtacaagacg ataaattaaa tctagagtat gaacttataa
     1741 atgaaagaat aaaaacaaac tacaggaatt atgaaaatat aaacgaagtt catgatagat
     1801 taaaatatgt ttatcatgat ttgaaaaacc atatgatttg tataaaaaat tatgacacta
     1861 aagaagaaat tatatcatat atagataact tagagtttca gataagtgaa tttgaacatt
     1921 ttaaaaatac tggaaataaa acattagatt taattttagc agaaaaaata agtatttgta
     1981 aaaagtatga tattcaaatt gaagataaca taaatatatc taaattaaac tttattgaaa
     2041 ataatgatat atgttcaata tttgcaaatt cactagataa tgcaattgaa gcatgtatgg
     2101 atataaataa tgagctagaa aaaagaatag aagttaaagc tacatatata aataaatttg
     2161 caataataaa atttataaat actaaggtaa atgatattaa acttattgat aaacgtattc
     2221 aaactagtaa ggatgatgat aagatacatg gaataggact tgctagtatt aaatatatag
     2281 taaataaata tggtggtgaa acaatagtta attactcaga taatgagttt atattaaaaa
     2341 taatgatacc aataaaaagt taggagagta caaaatgaaa aaaatagcgt taaacttact
     2401 taaaaacatc tcagcattaa gttttgggat agctgtatta tcagcaaaca gtgcaagttc
     2461 ttgggtagca catcaggcaa aagagccaca agctttacaa aaactaaaaa aataacatta
     2521 ataaaaggac ctcttcttat taaaggagag gttttacatg ttgaggagga aatatgttta
     2581 aaagattatc atataaattt gccaatatat tagttaataa tgagattgta gaaagtgaag
     2641 attttgaaat atatagatat ggatttgaaa ctttgattta tttcatagtt aatatttcgg
     2701 tagcattatt tataggaatt atttttgata gatttataca tacagttata tttttaagtt
     2761 gttattgcac tttaagacag ttcacaggag gttatcatgc taggaattat aaagagtgta
     2821 cattaacatt tgcagttatt tatttgataa ctattttttc agctaataat atagatataa
     2881 ataaatataa gtatttatta gtattattaa tgattattag tatactaaca atttacaagt
     2941 tagctccttt agaacataga aacaaacctc ttagtgaaag tgagaaaaag cattatagaa
     3001 agactgtgca aaaaatacta ttcgtaataa tatgtttaat tattttatgt aaaatactta
     3061 atatttttca gcaatatgtg atttatgcaa taatttctat atattggatt gctatattaa
     3121 tatatattgg aatgaaggtt aataatgatc agtaagatta taaaacattt tctaaattaa
     3181 ttaatttcac taattaatat taattttaaa aaataatgtc aaggtaaata tttgaactta
     3241 ttaaatatag ttgaatctat tgtaagttgt atcaaaggat tggctaggag gggcataaat
     3301 atgagtagta ttaaggttat atcagacttt ataaccaaaa taattagaaa aaatatttta
     3361 tttgcaataa cagttattat tataaattac catctcatac aacgatggac acatatatcc
     3421 aatagaggaa tttcatttaa tgattactta tccttgagtg tatatacttg tatgacaatt
     3481 agtattttaa ccatgttaaa tgtaattttt tatatgagaa aaagttatga tactgtaaaa
     3541 atattatgta gaaataattt tgattatttt ttaggtattt ctgttgctgt aactagaaac
     3601 aactttatat tttgttgcat accaattata tatgctatag catactcaag tttaataaga
     3661 acattatcaa ttgtaacgat taaatcaact atatttatat tggtatttga atggttttta
     3721 ccacttacta ttttatctat agtgatatca tttatttcag ttattataaa taatttaata
     3781 ctaaagatta ccttatcatc agtattttta tatttaacat caactaagat gttggataga
     3841 gttattgata ttaaagaacc attttttaaa gcattattta aatcacttaa tatatttgaa
     3901 gatcaatcat atgcttacta ttctgatttt gtagggaaag ttaataattc agcatatgtt
     3961 atagataaga ttatacctac actatttgca attactttaa taatagtagc atatctgata
     4021 ttaaatgata ttagaaagaa acagattaaa tcattaatag ttatagtagt gtacagtatt
     4081 ttatttattg gattaaatta tatatcaata gatatgtcaa catatagaga tgaggaacgt
     4141 agttatggag agtatttaaa gaaatctaat attagtgata ttaaaataaa atcgcatgat
     4201 atgaagattg actttaaaag caagtcaaat ataaaagata gaattgtttt attaaacaca
     4261 tcaaatgaag agttaacaaa tattaatatg attttagatg aaatatttga tataaaatat
     4321 ataaaagtaa attcggaaaa tataaaattt aacaaaaaaa aggatttaat tgaagttaat
     4381 ttaaaggaaa gtttagagcc taatgacgag gtgacattag atatagagta tgaaggctat
     4441 attaatgtgt tgacatcttg gaatcaaaat aaatatatag ctactaaaga tgatattatg
     4501 cttccaccag gttctttagc gtggtaccca aaagtaaatc aatcaagttg tatggcttat
     4561 aaaataaatt taagttctaa aaataatgtc tattcaaatt tacctttact gaataagact
     4621 agtaattttt taaaaaaaga ttatatattt gaaggaaagt caaatgatat tgcaatatat
     4681 gcaggtgagt ttaaagaaga ggtaaaagat gatataaaaa taatctatcc atcagatagt
     4741 aatgtaaata tggatataga ggaaaaaatt aaatttttaa ttgaaacaag aaatgaaata
     4801 ttaggtgata gcaaagcatc tgtagatgct aaaaaatatg tagatgaagt agataatgtt
     4861 atggaatcaa taaaaagaaa aaaaattaat atgatattag ttgctgactt acctagcaat
     4921 gaatttttat atgaagactc aaagggagag aaaattagca taactattta tcattggctt
     4981 tcaggaaata tccttataat agataaataa taaaggaggt taatatgata aacaagttag
     5041 aaataagaaa tctaaatttt aattacaaaa ataaaaaagc tctggataat ataaatttaa
     5101 ccctaacaga tggagtagtt gcattattag gtcctaatgg tgctggaaaa tcaacattaa
     5161 tgaggttatt agtgactctt tatgaaactt caattggaga gatagaatta aataatataa
     5221 agtatagcaa aaacaatgag aaaatcaagg caaatgtagg atatatacct caagattttg
     5281 atatgtataa taatataaat gggcaagaat acttagagtt tgtagctaaa atgagaggtg
     5341 tatctaagaa tgatttaaag aaacatatac aaaaagtagt atcaaaagtt aatctggaca
     5401 agtttataaa taataaaata ggtacatact caggtggtgt aaagagacga ctaggtatag
     5461 cacaggcttt aataggtgat tctaagttaa tagttatgga tgaacctaca gttggtcttg
     5521 atccagagca aaggaatgaa tttagaagat tgttaccaga aataagtaaa aattctatag
     5581 tattaatttc aactcacata gtagaagaca tacaatttaa ctgtgacaaa ttaattatat
     5641 taaatcaagg caaaatatta tatgatggta caattaataa atttattgat atggttgagg
     5701 tgtattcagt agtagtttct aatgatgaat ttgaatattt agaacgtaat attgatatta
     5761 ttgattatag aagagttaaa gatggtgtgc aagtaaagta tataggtaaa aatacagaga
     5821 aacttaagga tagcttaagg atagatacaa ctttacaaga tgcttatata aactttttac
     5881 ataaggagtt aaaataaatg tgtatattgg agttaataaa atttgagctt aaaaaaatag
     5941 agcttaaaca tgtgttaata tttgtaatta tttctatatt atgcatattt attacaggca
     6001 tattagatta taatgagtta atattttata atgatgtacc tataatggat acatattcta
     6061 tagcaggatg gttaggaatt ataaagatat cagatgtttt tataccaata atgtcagcaa
     6121 tcacaataat ttatgtgttt tcaaaagatt atttgggtaa tataaatgag atacttactt
     6181 tatataataa aaaaaaatat aatcaattta tagtatttag atggtgtgtt atattagcta
     6241 tatatactgt attattatta atttcaatta caatagtata tacatttacg tcagtgaaag
     6301 gttttaacat agacaaaata gattttgttt atagtgtaaa gccaatagat gtgtttttaa
     6361 agacatttcc tacattatta tggtatacaa catttccact aatgatatta acattaacaa
     6421 aaaatagatt tacaacaata gcaatattaa ttacatatac atttgctgat atatttttta
     6481 ttttacatat gtacccattt gttagtatga ttaatgtaaa tggattttat attcaaaaga
     6541 tgttttatat gcctaataat atagatgtta gatttaatga attaaagaat tatttcttta
     6601 taaatagagg ttctctagta gttatttcta taataatagt tttttatata gcaagaaaat
     6661 caacggtttt aaaaaagagt aaatagttta atatattttt tataatgtta tatttatata
     6721 gaatagtgac tttaaaaaat ttaaagccac tattttttaa tatgttttat ctatataact
     6781 attatttttc taggtttttt aatatttcgt aatagtgtgt tgtggctatt tcacttgact
     6841 cgcctttttt acaaaaagat aatttagata gttttggaac tacacgttca acgacaattt
     6901 tattacctat cattttagat tcaagtatct tcaatgcttc taaaaatctc ttatcctttt
     6961 ttgcacgatt ataaaatgat aaaacgtaga cataaaggaa taggttataa ttacggaaag
     7021 gatattcaac ttgcataaat aatgtgccaa ttccatagtg acaagggccg agtggttttt
     7081 taatagtcca atggtcaagt agaaaatcta cagctttgtc aagttttgat tctttattta
     7141 gataattact aaaacggaat gcatttaata tattaagagt tggtagtgga tttgagtatt
     7201 cagtttctgg acctcgacca aaactaaatt tattgcaacg ccacccacca tcagtatact
     7261 gtgtatctaa aaaatgttga aacgtttttt gcattctaat gtcagatgca tatcccatat
     7321 gacagagtac gttagcagca tttgcagtat gacaagggta aatacctcca tttggatata
     7381 gtttgaaacg tccatcttct cgccatgtgc taaatatcaa gtcagcacat tctttaagta
     7441 aagtatcatc agggttcaca cctaactcta atagataaag tacactatca agagtagaga
     7501 aaggagaacc ttttattaaa cgcttatcag gtgtagtcca atagtctgca ccattatcat
     7561 acctgtgtga taatattatt tcaatatctg ataaagattg attttctaca ttcatttttt
     7621 accccatttc atattatatt ctattaaatc tatcaaaaac tttattataa tattatttat
     7681 atttataatt gatttatttt atttaaaatt gcatttatag ctgtatcagg aacaactgct
     7741 aaatcttctg cattgaagta ataaactata ttagaatcaa ataatatatt tgaatttgga
     7801 ggaaattcat catctccaaa ccaaagtata aatatcatag atgtattacc catatatgta
     7861 aacctataag ctaaatctcc catgtttact ttttcagctc caattttctc cataactaac
     7921 ttatatttgt ctatttgaga tgtaaaaact tctgaaagcc tatatagagt cctgtttaaa
     7981 aaatttggat aataaacatt gcctcctggt atttctttaa aagttacata tttattagtt
     8041 ctagggatac ctttagcatt gattaaatat ctaactatca agattttaag ctcaaagtta
     8101 ttgcaaaggc taccattact attccaaact tctccacttg gatagtctat aatatattgt
     8161 ctatcaaaaa aattgagtgt gaatctattt aaatcattat tgaaaggtat attacttaaa
     8221 ttactaattg tatgagggtc taattctttg agtttttttc gaacatagtc aaatggaaca
     8281 ttataattat tttttgttat attttcatcc ataatttttt cctccaattt aaacaattaa
     8341 aagtgtattt ataaaaagtt ttctt
//
LOCUS       DAEQJM010000110         8141 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.113, whole genome shotgun sequence.
ACCESSION   DAEQJM010000110 DAEQJM010000000
VERSION     DAEQJM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8141
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.113"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            93..533
                     /locus_tag="KRQ43_003440"
     CDS             93..533
                     /locus_tag="KRQ43_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2743774.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     INLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            860..1087
                     /locus_tag="KRQ43_003441"
     CDS             860..1087
                     /locus_tag="KRQ43_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH2743775.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            1113..3233
                     /gene="feoB"
                     /locus_tag="KRQ43_003442"
     CDS             1113..3233
                     /gene="feoB"
                     /locus_tag="KRQ43_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH2743776.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(3366..4184)
                     /locus_tag="KRQ43_003443"
     CDS             complement(3366..4184)
                     /locus_tag="KRQ43_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2743777.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            4391..4675
                     /locus_tag="KRQ43_003444"
     CDS             4391..4675
                     /locus_tag="KRQ43_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743778.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     repeat_region   4843..5136
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4910..4938
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(5797..7890)
                     /locus_tag="KRQ43_003445"
     CDS             complement(5797..7890)
                     /locus_tag="KRQ43_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH2743779.1"
                     /translation="MNKRNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEQNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTILNKPIKINEFNEISNTKEGKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLIYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTQSHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         2881 a         1133 c         1005 g         3122 t
ORIGIN      
        1 aataaatata aattttaata aaggtattta tgttaaaaat ggtataatgt atcttaatat
       61 tcagtttttt aagatgctag gaggtaatta ctatgtttaa aattaaacac tttaatgatt
      121 tgagtttaga tgaattttat gaaatagcaa aatcaagata tgaggtattt gcttgtgaac
      181 agaagatatt ttcattaaac gattatgatg atatagataa aagctcttat cacatatttt
      241 taaaagaaaa tggattgatt tgtgcttatg ctagaataat tcctaaagaa tacagctctt
      301 ataatgatgt ttccattggt agagttttag ttctttctag tcatagaaga aaaggattag
      361 caaaacaaat gatggattgt gctatagatt ttataaaaat taacttacac gaaaataata
      421 taaccttatc agcacaaact tatataaaga acctttactt atcttgtggt tttaaagaaa
      481 tctcagaagt atacgacgaa gcaggtattg aacatattaa aatgagatta tagtgttgac
      541 aagctaatat tgttaatata taatttaagt ataaattaaa tattgaattg atatttaggt
      601 atttgaaaat accttacata gagtcaggag gcttttgctt tctgactttt ttattatcaa
      661 aattcaataa ttatatggat tcaaagtgtt aatttttatt ctatattcta ctttccccaa
      721 aagtaagaat tatacccaac tttgtatgat aggcatcttg cctatctttt ttttgtaaaa
      781 gtaacaaggt aataatataa tgcatagttt agaataagaa gattagccca ggctaaattt
      841 caagcatgga ggtgctacta tgaaaaacct taacgatatt caagtgaaaa aaactgtcaa
      901 agttgaagat atattatcta gtggtaattt aagagaaaga atgttagcgc ttggtcttac
      961 tagaggagct gttatagatg tagttagaaa aggtccaaaa aataatttaa ctgtctataa
     1021 aatcagaggt agtaagatag ctctacgaca agaagaaagt agcttaatat tagtttctga
     1081 catttaaaaa tttctagcag gaggatatta atatggggtt gacacataac tcaactaaaa
     1141 tgagttcttt aaaagatatg tttgatatag acaataagga agaccagttt gtaattgcat
     1201 tggctggcaa tccaaataca ggtaaaagta ctgtatttaa tcatcttaca gggcttagac
     1261 agcatactgg aaactggcca ggaaaaactg tagctacagc tcgtggtaat tttaaatata
     1321 aaaataccga atatgcatta atagatttac caggaacata ttctttattt gccttatcac
     1381 aagaagaaat tgtagctcgt gattttatat gttttggtaa tccagatgca gtaatagtag
     1441 tatgtgatgc tacatgtctt gaaagaaatt taaatttagt atttcaagtg atggaactta
     1501 cagataaagt tattttgtgt attaatttaa tagatgaagc tagaaaaaaa ggcattacta
     1561 ttgataaaaa acttttagag gattctcttg gtattccagt tattttaact gctgcaagaa
     1621 atggctctgg tatggatgaa ctattggata ctttaaatga tgtatctttt gacaaataca
     1681 aattaaataa taaacctgtt agatacaatg aaaatataga gaatgtggta aaatcaattc
     1741 aaccagaatt ggataatatt ataccaggta taaattctag atggttggga cttagactta
     1801 ttgatggcga tgaaagtata tttgaatcta tgagtaatta tatagacaaa gattctatag
     1861 atgctattaa tgaagtaaag aaaaagattc cagacaatat aaataaacag aaaataagag
     1921 atgagtttac taaaatcaac tatgattatg ctaaaaaact gagtgatgag tgttgttcta
     1981 atgttgctaa aaaatcaact gatagagaag aaaaagtaga taaaatatta acatctaaaa
     2041 tatttgggct tccaataatg ctcttattat taggtactat attgtggatt actatagaag
     2101 gggctaacta tccatccact ttattatcta atttattact cggatttgag ccaagtattt
     2161 cgggtatatt aaatagtatt aattgtccat catggttaaa tgatatgttg gttttaggat
     2221 tatacagaac attagcatgg gtaatctctg taatgctacc tcctatggca atattttttc
     2281 cattatttac cctacttgag gattttggat atttgccaag agttgcattt aacttagacc
     2341 acctatttaa aaaagcttgt gcacatggaa aacagtgttt gactatgtgt atgggatttg
     2401 gatgtaatgc agctggagtt attggttgta ggataattga ctctccaagg gaaagactta
     2461 tagctatact tacaaacaac tttgttcctt gtaatggtcg ttttcctact ttgatagcta
     2521 tatctacaat attttttagc tcagttataa ccaactcttt cgtatcaagc gtagcaactg
     2581 cactttgcat aactttactg ataattctag gtgttataat aacattgttg gtttcttata
     2641 ctctttctaa gacgctatta aaaggagttc cgtctacatt tacattagaa cttcctcctt
     2701 atagagttcc tcaaatagga agaactttat atacctctat aatagataga acaatatttg
     2761 ttttaggaag ggctgtaatg gtagccatac ctgctggtgt cataacttgg atatttgcaa
     2821 atatatatat aggagattta agcatattat cacatgttgc aaacttttta gaccctttag
     2881 ctaaattaat tggtcttgat ggttttatat tacttgcttt tattcttgga ttcccagcaa
     2941 atgagatagt tgtacctata cttttaatgg cttacctagc aactggttct atgatagaat
     3001 tagatagctt tagtgcttta ggtcaagttc ttagagaaca tggatggact tatttgacag
     3061 ctttaaatgt tatgctgttc agtttactgc attggccttg tgcaacaaca cttttaacaa
     3121 taaaaaaaga aactggtagt ttaaaatgga ctgccttagg attcttaatg cctactatac
     3181 ttgcttttgt tgtttgtttt ttaacaacta cagtttacaa tttatttata taattagtat
     3241 taactgacat tagacatata ttagagaaac tatttaaaaa tttatatact ttattataaa
     3301 gcatagagat atattcaatg ataagtaaaa ttacttaaca tttgaatata tctctatttt
     3361 aattcttatc tggatacttg aattgaaatt tcagtcatat aattatcttc attactttca
     3421 caaaaaaagt caagtatact ctcctcatac gaatttccaa taattttata ttcattttca
     3481 tatatatatt ttttcaattt ttcgtaagat ttatatgaat cctcatattt tccaatatgt
     3541 tttatgcaag catacattcc ttctggcttt acatatagct ttttatcctt tattttttta
     3601 tctatcttca aataaaaact tgatatactt aaatagtccc cattttttat attttcatta
     3661 cttactatta ctcccaactc atatccttga tacaaatttt tcgatttaca ataattggtg
     3721 aaatctatta attccatcat aaaatcacta ttactcatat tactcaaatc gcttgataga
     3781 actaaatatt cttcaaactt tttggatata taaatttctt cactattcat tttagaaatt
     3841 ccttcaactg ttatatttat tctattttgc atcttagagc ttatctttct tagttttttt
     3901 attttttctc ttatcttttt ttcttcttct ttaagcattt tcacacaaag ctggggagtt
     3961 ctattttgta tatactcttt tatttcctct aaactcattc ctatttctct taatgattgt
     4021 aatatatcaa gtgtatcata ttgataaact gagtaatatc tataattatt tttatcttta
     4081 tattcaggag aaaaaatacc tattttgtca tagaaaatta atgtctgctt agatatacca
     4141 cacaatttag caaattcacc tgttgtaaaa tactgttttt ccaagggtta tacactcctt
     4201 ttctttttgt tgtctatata gttactatat tctttattat ttactaaatc aagtagttat
     4261 tattttagaa aatcaatatg gttttgattt taaagcttaa atatcagtta gatgtcagtt
     4321 ataaatattt tatccattcc tctcataaaa aagatatccc ctcttaactt ttggatggaa
     4381 tattatattt atgcttgtta gagtgaaaat tgtaataggt gctacaataa gatatttaat
     4441 taaacataaa gttaattatt gtaataaaaa atctttagat aaattagagt taaagtatgg
     4501 aaatatagat agagaaaaag ctgttaaact agaaatattt tatcaatatt taatagaact
     4561 tgaatatata gaaatgagtt tattaataag aagattagat actgcaataa catcattagc
     4621 attagtatct attataacaa tagcatcata ttatttaatc agaaaaaatg tgtaattatg
     4681 taagctattt ataataaaac actgataaaa ttaataataa aaaggtaata ggatttctat
     4741 actacctttt ggtttttata atatagtgta attttattat atttttgtat gctaatataa
     4801 ctagataatc ataagataac acattaaaag aaaattataa aaatttatat tccgtatagt
     4861 tagtataaaa cgtaagtaat ataaatttat gtaaaacaac aaaagatgga tttacattcc
     4921 atatagttaa tataaaacgt tttaatgaat taacagaaga tgaaagtttt atatgtattt
     4981 acattccata tagttaatat aaaaccattg aaaatagtga cttttacgaa aaatttgcta
     5041 aaatttacat tccatatagt taatataaaa cacttcctat taaatccaca ttaggaaatt
     5101 ctccgagatt tacattccat atagttaata taaaacccca aaataaactt agtattttca
     5161 acacttacac gtatacaact ctcctaaatt tgcagtgaac gagcaatagt gcaattgata
     5221 acgcttatca tgcactctca acaccttata tttcaactgt tacgccaaat tttatcacaa
     5281 atatagctca ctgcaaaatt tctataattt tattatatca taaatatatt acttttgaat
     5341 attgatacca atttatacca taataaaagc aagaaaaaac gtaatctatc tacattggat
     5401 ttaaattcta taacttaaag ttttttacat aatatttatg cttgtttaat caatctaata
     5461 tatcattctt gtatattgct tttaatagtc ttttttctta aataaatatc tatctgaaca
     5521 agcatagttt aattaaaaac ttttgtattc ccttaaaact gtatctacct cttattattt
     5581 tatttatgat atattatttt taatctaaaa atagatatct atttttatta tagttatccc
     5641 tttttaaaat actttaatca tatactactc ctaatttaac atcccttgaa atgctatttt
     5701 cttatattgc aatttataat tgatatatct tcaatataat aatttaatgt atttttgatt
     5761 ttaaagcttt tcagtgatat tattgataaa ttagaattaa ttatctagct ttaaaaggtc
     5821 aaagatttct gttgctgtct gcggttttcc aaataaatat ccttgtatgt aatctggctt
     5881 tatttgttta actaaatcat actcttcttg tgtttctaca ccttctaaac atacttttat
     5941 tcctacatca tgacaaattg caacaataaa atgtataaat gtagcatcaa acttactctt
     6001 taatatatct ttaacaaata ctctatcaat tttcactata tctattggag aaaattttaa
     6061 aacttctaga gacgagtatc cagtaccaaa atcatccata gcaatataaa ttcctaaatc
     6121 ttgtaaagcc ttaaatttaa actgtaaaat actcatattt tgtactgtat gactttctgt
     6181 caattctaaa acaagatttt gataaggaaa attttcatca tctataattt ttactatatc
     6241 ttcaataaat gtgtcttcta atatttgaac agctgaaacg tttacactca ctttaaaaaa
     6301 aggatagtaa tcaatccatt tcctaaaagt acgtaatgcc attcgaagca cccaagcccc
     6361 tacaatattt atcatatcat tttcttctaa tattggaata aattccaaag gagaaattgc
     6421 tttgcatttg tcattagtcc accttaaaag aacttctaca cctattattt tatgactttg
     6481 tgtatctact tgtggctgga atcgaagact aaatccccta aaatcatcat taattgatgc
     6541 ctttaaatcc cgcatcattt ctaatgaata cattttattt tttaatattt cttgggagaa
     6601 aaaaacaagc ctgtttttac catgctcttt cgcatattgt aaagagtaac tagcgcattt
     6661 ataaagttct tttactgtat ctccatgttt tggatatatt acacaaccag cagaaattgt
     6721 tatatttaat ccatattttc tccatagttg aaggtgtata atcatattct gtatttgatt
     6781 atatagagtt agaatttcat tttcttcaac attatcaaca agaataccca tttcgtcccc
     6841 atcaagttta taaagttcag cattatctgg taaaatagat tgtatagact gtgctagtgt
     6901 ttttattata ttatctccaa aatccctatc atacatctca ttaacatttt taaaatcgtc
     6961 aatatttaat aatactatgc ataatttttc aatcatagga tttgaaattt tatcttcaaa
     7021 tacactcata aattcatgat aattcagtaa ctgtgtcaat gaatcaatct tattttgttt
     7081 acctaattgc gtcattattc ctgcaaaaat acttggttct ccaaattcat cacgcattag
     7141 ttgtcctcta catcttaacc atatatattc tccactacga tttttagccc taaattccac
     7201 tgtatgataa tccatctggt ttttacctat ttcagtgttt gacttataaa aacgattcca
     7261 gtcttctgga tgtacaattt ttttccagta aataagcgga ttttcaacaa tttctcctgg
     7321 taagtcaaat aattcaactt gtgatggtga atatcgaaat acgcctgttt tcatattaca
     7381 aatgtatata tattcatctg tacctctaat caaagcatca taaagcaatg tagaattata
     7441 atcaaaattg tctcttgaaa aattaaaaac tccttttcct tctttagtat ttgatatttc
     7501 attaaattca ttaatcttaa ttggtttatt taagattgtt gagtttgcaa tatctattga
     7561 ttgatgcata tgaacaactg tgccatcttg ccatgtaatt aaactatcat aattttcaaa
     7621 aacacgattt aacttattac atttttcata ccactttatt aatactcctt ttttatcatt
     7681 ctttaatagt tctaaaactt tacaaaaact acaagtagaa ttttgctcag gatataatac
     7741 ttgccagcaa acttttcctt ctggatctaa aatattatat tcttctttca ttttcttgtt
     7801 cataaaaata atttcattag tatgaatatt tgtaacatat atattaatct gtagttgatt
     7861 taatataact tcaaaattac gtttgttcat atacttatct cctccatagt tactgctctt
     7921 tataacaaca ctgttaaaat tattcttttt agaagattta cttataactt atacatacac
     7981 actaaatacc ttaatttaat tagaaagttt attatttcat attttaaatt ataattgata
     8041 aaaaaaaata cagcaatata gtattaccaa tttaaaaaaa attaatatta cataatacat
     8101 ctctctctta tattaaattt taacttggta ctaatcttga c
//
LOCUS       DAEQJM010000111         8113 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.114, whole genome shotgun sequence.
ACCESSION   DAEQJM010000111 DAEQJM010000000
VERSION     DAEQJM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8113
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.114"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..538
                     /locus_tag="KRQ43_003446"
     CDS             <1..538
                     /locus_tag="KRQ43_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH2743780.1"
                     /translation="TMNELAKEVEYTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKI
                     ESAKGKTGFEKIKLSYFAFHKFYSVEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFN
                     KFMFDEIQGMFEIGKNDRSIRHDIEIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNID
                     EEKFIETTLALLIDSIKA"
     gene            683..1345
                     /locus_tag="KRQ43_003447"
     CDS             683..1345
                     /locus_tag="KRQ43_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743781.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCGNISLNKVEVKAYLDNVEVLLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            1345..2526
                     /locus_tag="KRQ43_003448"
     CDS             1345..2526
                     /locus_tag="KRQ43_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2743782.1"
                     /translation="MKTPRNINSTVVFIIFCLIITFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(2707..5367)
                     /locus_tag="KRQ43_003449"
     CDS             complement(2707..5367)
                     /locus_tag="KRQ43_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743783.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAQKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDRTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKMS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKTVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNTRSRRQEFAMLRSVGLSPE
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5364..6047)
                     /locus_tag="KRQ43_003450"
     CDS             complement(5364..6047)
                     /locus_tag="KRQ43_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743784.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(6391..7329)
                     /gene="blaCDD"
                     /locus_tag="KRQ43_003451"
     CDS             complement(6391..7329)
                     /gene="blaCDD"
                     /locus_tag="KRQ43_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH2743785.1"
                     /translation="MKRKNNFIWIVILLVVVAMGVYYVGRKHNNTKQKHDKNHINSEL
                     NKSKVENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETRRSPCS
                     TFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYYKKLID
                     KVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMAKI
                     FEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMLEREGD
                     TYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(7357..8073)
                     /locus_tag="KRQ43_003452"
     CDS             complement(7357..8073)
                     /locus_tag="KRQ43_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743786.1"
                     /translation="MILIVILSIFIIASINIIILGKENIRDIVIPLTLFIVSDFLFLC
                     GNIICRGGVMLLFIGLFAIPLMLIAFIWICVHMIKLYYKKDLNKRKMIGCIFSIFISI
                     GTIFIPSPSESFRFKLYEKDYSVVAKAILKVYDEKKLSSESVFYIQSDKNELEKIFSK
                     EVIKKMKKLNRNLDVVKISGNRNLVYFFFGAELQSIDGIVIFKDLKHVKPKLDFINRS
                     IQAPRLEYITNNVYYFKGEL"
BASE COUNT         2797 a         1287 c         1013 g         3016 t
ORIGIN      
        1 aactatgaat gagttggcaa aagaagttga atatactaaa cgcaccatat acaagtactt
       61 ttcatgtaaa gaagatttat tctttgctgt tgtcttaaga ggatataaaa gactttggga
      121 taatgttaaa atagaaagtg caaaaggcaa aacagggttt gaaaaaataa aactttcata
      181 ctttgctttt cataaatttt actctgtaga accttctcta ttatgcctta tgggaatgat
      241 tggtattgta aactctgaaa aatcggatac tgatatgctg tttaaagaaa agtttttttc
      301 ttttaataaa tttatgtttg atgaaataca aggaatgttt gaaattggaa aaaatgatag
      361 aagtattagg catgatattg aaatacctac tctcatgtat tcatcaatat ttacacttac
      421 aggatttttt aatttactat ctgtaacagg aaagtcatac ctgaacaact ttaatataga
      481 tgaggaaaaa tttattgaaa caactcttgc tcttttaata gattcaatta aagcataaac
      541 ctaagtttat aaattaaagt ttatatactt aaatgataat tttttctatc tctaacttct
      601 atctctaaca taaaaaatat taaacataaa actaataact tagttaatga aataactaaa
      661 ttactgaaag gactaaaagt aaatggctaa aatacttctt ttagaagatg atgatacaat
      721 tacatttgga ataaaaactt cccttgaaaa gaaaaatcac actgtatgtt gttataatac
      781 gattgctgaa gctaaaaaaa attttgataa aactattgat ttaattctgc ttgatttaaa
      841 tctacctgat ggtattggat acgagttttg ccaatatgtt aaaagtatag aagatactcc
      901 agtgatattt ttgacagtcc gtgatgatga aaaagacatt atacgtggat tagatatggg
      961 tgcagatgac tatgtggtta aaccatttct gctctcagta cttcaatcca gaattaatgc
     1021 agttcttaga agaactcatt caaatactaa caatactatt acatgtggaa atataagctt
     1081 gaataaagtt gaagtcaaag catatttaga taatgttgaa gtacttttga cagcaggaga
     1141 atataaactt cttctaagtc ttatggaaaa taaaaataga gctatgaccc gtacaaagtt
     1201 actagaaatg ctctgggatg tagatggtaa tttcgtaaat gataacactc ttactgttac
     1261 aataaagcgt cttagagaaa aattaaaaaa tccaccttgt ataaaaacat taagaggcat
     1321 aggatataga atggaggaca gctagtgaaa actccaagaa atatcaacag tacagttgtt
     1381 tttataatat tctgcttaat tataactttt ttattaagtg taattctaac aactataact
     1441 tcttttaatg aatacaatgt actgtctaag gctcttggtg catcatatga gtacaatcct
     1501 aagtctacag aaagtatact aaaatcactg aaaaattcta gtgataagga ttttaaaaca
     1561 ggaaatgaaa ttttatcaaa acatggatat tctaaaagta cattttggag taaaaacttt
     1621 ttttattttc tagtgatatc gtttggtata atttcaacaa tggctacagt tgtatatata
     1681 atcaaacata gaacaaataa gcaaaaactg agtagaataa acaatcttac tcaatactta
     1741 gaagaagtga atttaggaaa agagtctgta cttttacgat gtgaagatga attttctcac
     1801 cttgaagatg agatatataa aacagttggg gaacttcgtt gttcaaaaga atttgcttta
     1861 aaagaaagac aaactctttc agataatctt gcagatattg ctcatcaact taagactcca
     1921 attacttcta tgtcacttat ggcacaatta ctttcagaaa attgtccaga tgaagaaata
     1981 gattatatta acagacttac aaatcaaatc tcaagacttg agagactagt ttcatcttta
     2041 cttacattat caaaattgga tgcaagtact ttaatatttg aaagcaaact tatagatgta
     2101 cattctcttc ttacttatgc aattgagcct atagaaggtt ctttaagaga aaaacatcag
     2161 acatttacta tcgaggcttc tccttcggta gaatttgaaa tcgatattaa ttggacttta
     2221 gaagctcttt taaatattct taaaaattgt agtgagcata tagaagatgg tggatatata
     2281 gttgcttatt atagtcaaaa tcctctatat gttgagatta tcatagaaga taatggtaaa
     2341 gggtttgctc aggaagaact tccatatatt tttaatagat tttatcgtgg taaaaatgct
     2401 agtaaggaca gtattggtat agggcttgct ctatcaaagt ctattataga acgtcaaaat
     2461 ggtactctac atgcagaaaa ttgccataat ggtggtgcaa gattcataat taaattttac
     2521 acataaaatg ctggattata ggtaaaatac ctataatcca gctatatcta tattctatgt
     2581 tatctattgt tttagtaata tacttctatt tacatttaag gttttattaa acaaacaaat
     2641 taactatccc tatacttgta agtagtctta aatcgaaacc tttaaataag ttcaaatagc
     2701 ttttgtttat attgtttcat tttttataga ttctactata ttttcattct tcaactgctt
     2761 gtatcctgtc atatatgatg ctattacaat aaaaagtatc aatatagtaa aacctattat
     2821 tgtagatata ggtgcaaatg gtaaatactc tataaaatat atttcattta tacgtagaaa
     2881 agcatacact attcctattt gcacaggaat actaagtagt aatggtgtaa ttcctaagaa
     2941 caaaccttcc aaaacaagca tcttttttat gccttctgga gataatccaa cagaacgcaa
     3001 catagcaaac tcttgtcgtc tacttctagt atttcctgac actgtagcaa gtacatttga
     3061 taatccaatc atagccaata aacctgtaat aaagcctact attaaattca tggtctttat
     3121 tccactagcc ttttgttttt cactttctaa aacatcctca atactataat ctcctgaacc
     3181 atagtcttta ttataaatgg actctaattt ttctcttact ctaggaatgt cctcacgatt
     3241 atttacttta aatactccta tcagcctatt tgaacgtaac ctacttactt catcataatt
     3301 tttagatatt tcctgcacca tagacattgg cactatttgc attaatgtat attttgaact
     3361 agtatctact gttttaggaa gtgtgcttgt aatagctccc actttcatgt tgtaagtata
     3421 atccccttta tcttcgtcat atactttttc atttaattta atgttatctc ctattgaaag
     3481 atttaaataa tctatatata ctttatttct acgtgtacta cgattaatat cttcctcctt
     3541 attatataca attgaggttg gattttttgt atcataaaat aactttgggt ctacagaaat
     3601 ttgcctacaa tattctgtaa aactcttatc atcaagccca attatatttg aaattatacg
     3661 aaacttgcca tcacgttcta taggagagta ttttttagat gaaactatac ttttaaatcc
     3721 tccatttttc gcaagttctt ttgatgcatc tttttcagtc agccaagtgg aagcagacat
     3781 tttttgataa tatagtgaac tttttacacc ttctgtatta tctaattttt caatgaaagc
     3841 agactctaca ggttcactat tttccaaata aactgctata tctctttggt ccttataatt
     3901 atcacttcca taaacagctt ttgctccttc ttgatttgca attatatgca aaaaacatgt
     3961 aagtaataaa aaagataatg ttaaagatat tgttgcagta cgataagatt ttttacgagc
     4021 acgtagtgcg tttgatgcaa gttctccttc tattccaaat atctttccta atgaatattt
     4081 atgcgacttt ttgattttaa cactatctcc ttgtcgtatt gcttctatag gagatatctt
     4141 tgatactttt cgtgctggta taagtgcaga aatccagact gttactattg taagtaaaac
     4201 tgctggcaga aaagcaggaa taccataagt aaataccact tctggaacat cagtatgata
     4261 attaactgaa ttaatataaa ctataagcct attacacaat aaccatccta aaaataaacc
     4321 tattggcaat ggtataattg taagcaaaaa accttcaaac actacagaca ttttaatctg
     4381 ttttggtgat gcaccaacac tagataatat ccctaattga gtaagtctag catttgcaga
     4441 tagtgaaaac gcgttgtaaa tcaccattac aaacacagct actgtaaaaa ttgctattgt
     4501 aagatacata ataggagttg aaaattttga tatactgctc atagatgctt tctgttctgg
     4561 ggaaaagact aacattttta aaagataatt actattatat ttaagattgt attttccata
     4621 ttcattagtc ttccacccca atgatttagc aagttttgga agttccttgt atgtgtctct
     4681 tatattttta aatcgcaagt acacagttat actatcatta ggttttatac ttgttctatc
     4741 aagatatcca agagctgtat atgcaggtat tactgatgaa gtggaaacat ctacctttcc
     4801 tactattgtc aatgtagtct ctgaaatttt tttaaaactt tcccctttcg atttttgagc
     4861 tatgggttca agaggctttc catttaggat tctatctcct attggaagag taattttatc
     4921 cccaattttt acacttggat tattctcaaa atattgtttt gataatgcaa tttcattagc
     4981 attatttggt cgacgaccct ctattatagt atccttttct ggcatagaat tccaatactc
     5041 tgatgtagca tttctataaa ttatataatc tcttttctca tcattaattt tgcctacata
     5101 ccattgtcct tttaccatta catcatcaac tgaagaaaaa ttttcaatta atggtaagtc
     5161 acttccataa gtatagtcaa acaattcacc atgccagtta ccttctttct caattgaaag
     5221 tcttataaaa tctgtccaca tggtatacaa cagtccacac aaagaagaca tcatggttgt
     5281 agtaagtaat atagctaaca ttatagctat actactacgt ttattgcgtc gtacaaagtc
     5341 taaggtgtat tcttgaagaa tattcatttc ttcaccacct tttcagagac aatcactcca
     5401 tcttccatag ttacaatacg atttgcctct agtgctattt tctcatcatg agtaataaga
     5461 agtattgtct gattaaatcg tttatttgat aagtttaaca agtctacaat ttcttctgaa
     5521 ttttttctat caagattacc agttggctca tctgctaata aaatagctgg tctatagatt
     5581 aaacttctag ctatagatac cctttgttgt tgtccacctg aaagttgact tggaagatgg
     5641 tttaatctat cagataatcc caatatagat acaatctcag agaatctatc ctcatccacc
     5701 tttcttttat caagtaacat gggtaataat atattttttc taacatcaag ggtaggtata
     5761 agattataaa attgataaat aagacctact tttctacgtc taaaaactgc aagagcttct
     5821 tcctttaaac ttgatatttc tgtatcttca acataaatct ttccagatgt aggtctatct
     5881 actcccccaa gcagatgtaa caatgtagat ttgccagaac cagatgctcc tacaatggat
     5941 acaaaatcac ctttttgaac tgataaattt acattattaa gggctgtcac tctggtttga
     6001 tttgaaccat atatttttgt gagattttca cattttaata tttccatata caatcatctc
     6061 ctttatggtt aaattttagc aacctaaaat gacattatag tgacatgaat acaaatataa
     6121 attactatta aaaatattgt ttagtttttg cacattattt aaaattataa tataaaacaa
     6181 aaactatgca atatatttta tttatacttt taatatatta catagtcttt aaaaggtatt
     6241 aactttaaat ctataggtat tcaatttaat aatcaatagc aagtatttta tgtactaaag
     6301 gagttttgct ctatatagac tcaatttagt aaaattattt aataaatatt acagactata
     6361 ggtaaataat atttacaaat aaaattaagt ttattccctt acactataat atttcttaat
     6421 tatattaatt gcaatttcct ttacctttgg ccctgtaatt tctttattgg aatcatctga
     6481 tttaatagca aaataatagg tgtcaccttc acgctctagc ataccaacaa accatgcatc
     6541 cacacgttta tttttttcat caaatcctgt tccagttttt ccatatacat ttatgttttt
     6601 atcatttaca tctattttca taatatctct taaaatatta atatgctctt ttttaaagtt
     6661 tgtatctccc tcaaatattt ttgccattgt ttgcacttgt tcttttggag atatttgtaa
     6721 tgaagattct aaccaaaatc catttaaatg tccctttcca ttttttaaat ctccttccca
     6781 ttcgctaata tcgcaattcc catactttaa atcatctaaa atgttttgga cagatttagc
     6841 atcaacttta tctatcaatt ttttgtagta ccaaacacaa gactccttaa atgcctcttc
     6901 taaactaaga tttttattcc aatttttatt tggatactct gtaccatcat atcccataac
     6961 tgattctttt gagtttatta cccctttttc taaaccaatt aaagttgaaa ctattttaaa
     7021 agtagaacat ggtgaccttc ttgtttcaat taattctttg ttatatatat tatattcttt
     7081 atttttagta ttataaaaaa tagctcctcc actaatacct tcaaaacagt cactatagtc
     7141 aaccatatta attttttctt ttttgttttt atcattgttt tcaactttgg atttatttaa
     7201 ttcagagttt atatgattct tatcatgttt ttgttttgtg ttgttatgct ttcttcctac
     7261 ataatatact cccatagcta caacaactag aagaataact atccaaataa aattattttt
     7321 tcttttcata ctttatacca tctcctctac ataagtttat agttcacctt taaaataata
     7381 tacattattt gtaatatact ccaatctagg agcttgaata cttctattta taaaatctaa
     7441 ctttggttta acatgtttta aatctttaaa aatcacaata ccatcaatag attgtaattc
     7501 agctccaaag aaaaaataga ctaaatttct attcccagaa attttaacta catctaaatt
     7561 tctgtttagt tttttcattt tttttattac ttctttagaa aatatcttct ccaattcatt
     7621 tttatcagat tgaatataaa agacagattc agagcttaac tttttttcat cataaacttt
     7681 caaaatagct ttagctacta cactataatc tttttcataa agtttaaatc taaaactttc
     7741 acttggacta ggaataaata tagtacctat acttataaag atactaaata tacatccaat
     7801 catttttctt ttatttaaat cttttttata gtaaagctta atcatatgta cacaaatcca
     7861 tataaatgca attagcatca atggtattgc aaataaacct ataaatagta gcattactcc
     7921 tcccctacat attatatttc cacacaaaaa taaaaaatca cttacaataa atagagttaa
     7981 agggataact atatctctta tattttcttt acctaatata attatgttga ttgaggctat
     8041 gatgaatata ctcaatataa ctattagtat cattatgtcc tcctttcagt ttgtgaggta
     8101 attatttatt ctc
//
LOCUS       DAEQJM010000112         8080 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.115, whole genome shotgun sequence.
ACCESSION   DAEQJM010000112 DAEQJM010000000
VERSION     DAEQJM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8080
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.115"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..408
                     /locus_tag="KRQ43_003453"
     CDS             <1..408
                     /locus_tag="KRQ43_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2743787.1"
                     /translation="FGGKIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFFYD
                     LVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVTCK
                     LYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            873..2087
                     /locus_tag="KRQ43_003454"
     CDS             873..2087
                     /locus_tag="KRQ43_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743788.1"
                     /translation="MQIKIGKVIQRLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEKVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNIFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLWYANLSLEIKKMLSEDKGAFFSMYVDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(2507..3028)
                     /locus_tag="KRQ43_003455"
     CDS             complement(2507..3028)
                     /locus_tag="KRQ43_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2743789.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHEQRKSYLQTEILKNKE
                     YQFNLIYDKNQFVGIILCWETDNFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            3384..4181
                     /locus_tag="KRQ43_003456"
     CDS             3384..4181
                     /locus_tag="KRQ43_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH2743790.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            4291..4881
                     /locus_tag="KRQ43_003457"
     CDS             4291..4881
                     /locus_tag="KRQ43_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBH2743791.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNEETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFADFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            4947..6644
                     /locus_tag="KRQ43_003458"
     CDS             4947..6644
                     /locus_tag="KRQ43_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH2743792.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGISLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     NVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            6858..7697
                     /locus_tag="KRQ43_003459"
     CDS             6858..7697
                     /locus_tag="KRQ43_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBH2743793.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
BASE COUNT         3230 a          774 c         1339 g         2737 t
ORIGIN      
        1 tttggtggca aaataataag aagaaatgaa aagactaagt ttgactggtt aagtagagat
       61 aaagaacaag ttgaaaaata tataaatgac ccattttgtg gagtagtgtg tagttgtggc
      121 tttttttatg atttagttca agggttaaaa gaaattgagg ataaagaaaa cttaaaaaaa
      181 gtgccacttg atatacctat ttacataata tctggagata aagaccccat aggaaaaaat
      241 ggtaaaggag tcttaagact aagggataga tatataaaat taggagtaaa agatgtaact
      301 tgcaaacttt acaaagatgg aaggcatgaa ttgttgaatg aaataaatag agaagaagtt
      361 tttgaggata taatttgttg gttaaacaat aaaatagaaa tattgtaata aaaaaatata
      421 atgatatatt tgctttaaat ttatttatat ataatatttg aaaagtggat tatgtatatg
      481 caaagtagaa aagagagagc ctagaagtga ttttttgcta taatgccatt tattgaatag
      541 gtgggtgtta ttataaataa attattaaca ctcagtatta ttatcattgt atatggaatt
      601 tattttattt aaaattcctt gaaagtttaa atatagtaag ttgtagtaaa gagaaaatct
      661 aaatatttaa atgctattta atgtgaatct attaattagg ttatacttaa acttaattaa
      721 tagattttat atttcaagcc aatgagatag ggttttagat taaaatataa ccaatggtta
      781 aattacagac attttgttaa ctttccctcg atttactagt aaatattttt tttatatact
      841 taaattacaa cagatgtact agggaggtat atatgcaaat taaaataggt aaagtcatac
      901 agcgtcttag aaaagaacga aatttaactc aagaacaatt agcaaagttt ataggtgtgt
      961 caacaccagc agtatctaag tgggagagtg gaaattctta cccagatata gaattattgc
     1021 ctttattagc agactttttt aatgtgtcta ttgataagct tttaaattac aagattgatt
     1081 taagtgaaga aaaagtaatg aaaatttata aagaattaga atcaggcttt gctagaattg
     1141 aaattgattt atcaacagaa gaaccaaaag aagaatttag acaagactta gaatctgtaa
     1201 aaaagctttc taatatgtat atagagaagt atcctaaaag ctatttattg aagctaagga
     1261 tatgttcgct gtatcagatg tattcatata aatttggtaa gagtgaactt aatgacagag
     1321 taaaagaaac aacgaatatt cttgaagata tagtgagaaa tacagatgat atccaaataa
     1381 aagaaacagc tcttattata ttatcaaacg catattgtat gttggaagat tatgaaaagg
     1441 cagagttgta tttaaatatg atacataagt caatagggga tacaagtgtt aatttagcta
     1501 tgatatattt aaagcaaaat agacttgaag aagcagaaat attgcttcaa aataaattgt
     1561 ttagtaatat atttaatata agcatggatt gtaagggaat aattaatgta tacaaaaatc
     1621 aatacaagga attaaagaaa aaattggaga atagaaattt taataaaaat gcaattgaga
     1681 gagaaatgga gtatataaaa aataagttgc tgtggtatgc aaatctttct ttagaaataa
     1741 aaaaaatgct cagtgaagat aaaggtgcat tttttagtat gtatgtggat tatatggaat
     1801 tatctctaat ttttttattt tttaacatga aagaagaagc aaaaaaagcc ttatatagtc
     1861 taaaagaaat attagaaaaa tatcctatac atgaaagttt ggatgtaagt caaatgagat
     1921 tttttgataa ggtagagtct aaaaatttat atacttttaa tatatataca aacttgttaa
     1981 ttgtacttaa tgatgacagt tataatgagc ttagagaaga accaattttt aaggatgtaa
     2041 ttgaaaagat tttagatatg gaaaaaatgt tgaaaaataa agaataagta aaaatttaat
     2101 ataggactta aagattaatc aaattaaaag aaagtgtttc aaaataaaaa tttgaatcac
     2161 cttttttgtt ggtcttaaac cgttatttag aaaaatagag gtttcaaaat agaaatctga
     2221 attatctgta ttattacaca aaaatagaaa cctaaattta taaaaataga ataaagtttg
     2281 ttatataaaa tgtaattttg tctataaaat ctcacatgtt ttcttaactt taagcgtgaa
     2341 aaagaggatg tatcatgaat tttttagttc atgatgcatc cttatttgta tgaaatccaa
     2401 tatatcttta ttatttaaac aatggaaaag agtcttattt ctattttgag acatctcttt
     2461 tatttaatta tgaagtttta tacagttcaa taaataggaa ttatatttag aaactcatga
     2521 cattatttct tagatagtga ttaaatttat catattccat tttagataac ttttctgggt
     2581 aagacattac aatcaggtta tgcccattga atttttcatg gtatggtgga tgaatgtgtt
     2641 cataattatt tgtcttatat tttactcttt catagaacgc cttgcgataa attgaaatct
     2701 catcaattgg aaggtcaatt tctaaaataa tagtttttcc tttcttattt aaaagctcta
     2761 acgctctttg tccatatcta ttattgcgca tttctggaaa aatgcagaaa tgttctacat
     2821 agataaagtt atctgtttcc caacataaaa ttatgccgac aaactggttt ttatcataaa
     2881 ttaaattgaa ttgatattct ttatttttca aaatttctgt ttgcaaataa gattttcttt
     2941 gttcatgaaa tgggaaacta attttatata attccatagc cttgtaatat aatttatttt
     3001 cactggttct taaccgttca aatttcactt tactcctcct aatcacgaaa attccaattt
     3061 atttatgagt tcattttacc atagtcagta tttgcataca atgtgtttta agttgagtgt
     3121 catttctttc ttttatttat gcttatatct catagactaa gagataattg cttaagacat
     3181 aactaaaaac tattatatta agctttgata atctaaaaac agtatattta tggacttttc
     3241 taggtctaaa agtaatctta ataattttag aagttacaaa aaagttacat aaatttggaa
     3301 agctataata tacatatata atataaggtt aaaactgtaa tgaataatat taatttaaaa
     3361 tttgaacatg gaaggagatt attatggaga aaagagaaaa gaggataata atatcatctt
     3421 tattaagtgt atcaatttta atgggtttgg taagtatata ttctatatta aataaagaag
     3481 acataatttt aactgttaag ggtcaagagc aaaaagtatc ttcctttaag aaaacagttg
     3541 aggaactttt ggatgaacag ggtgtaaagt ataattctga agataagatt aatccaagtt
     3601 tagatacaga actaaaagat gatatgaaaa taaaagttgt taaggtaact aaaagtaaaa
     3661 aagaagagat tgaaaaaatt ccatttgata caaagcatgt aaatgatagt aatttgttaa
     3721 aaggaaaatc taaagtttat caagaaggtc aagaaggaga aaaaaaacta gtctataatt
     3781 taacttacca tgatggaaaa ttagtcaaaa aagtcttatc aaaagaagta atatctaagg
     3841 agccaactac aaaaattata aaatatggaa ctaaagaaaa agtactaata gcatcaagag
     3901 gagcaaatat aagaggaggc aaacatatga aagtggttgc cactgcatat gcaggagata
     3961 caataacatc tactggtaca actccaagat ggggtgttat tgcagttgac ccacgtgtaa
     4021 taccatatgg aacaaaagta tatataccta aactgggtat gacttttgta gcagaagatt
     4081 gtggaggtgc aattaaaggt aatagaatag acatttttat gaacagtgaa ggaaaagctt
     4141 caaattgggg aaggaaaagt atagatatat atctacatta aattagtgaa tagaataact
     4201 ttacttgaag gacaaaaaag tataaaatat gaattaacta aactgttaga ttattcttaa
     4261 aacataaaaa tatatctaag gggggataag atgaaaatag tctgcttagg agacagttta
     4321 acgtatggat ttggagtatc acgaagtaat tcatggacaa acattgtaaa tgaagagact
     4381 cgattagaaa tagtaaataa gggtataaat ggtgatacaa caagtggtat gttagctagg
     4441 tttaatgaag atgttgtaaa aaactctcct gatatagttt ttataatggg tggcactaat
     4501 gattttattg ctggtgcggg aaatgaaatt attaattcta atataatggc tatggtgcat
     4561 cagtcatatt caaaaaatat tatacctata ataggtatac cattaaaacc agatattcca
     4621 aatgttaggg aagattggag ttgttttact gattttaata tagtatctca aaacttagaa
     4681 tcatatagtt attggataaa aaaattttgt atgacattta atactaattt cgcagatttt
     4741 tattcagaat ataataaaaa tatggaacta gaaggatata aaaaattata ttttgatggg
     4801 ttacatccaa ccaaagaggg tcatagaata atggcagaca tttttattaa ttcaattaat
     4861 aagtatatag aagagttata gattacatta aaatgcttgt ttatgcgtca gttgcaataa
     4921 atacatacag tagagagggg tttattatgg attatactaa aacttatgaa gagtggataa
     4981 agggttcata ttttgatgaa gatacaaagc tagagttgga gaatataaaa aataatgaaa
     5041 aagaaataga ggatagattc tataaggatt tagaatttgg gactgcgggt cttagaggaa
     5101 taattgaagc aggaacgaat agaataaata agtacacagt tagaagagct acttttggat
     5161 tggcaaacta tatattagaa aacacaacaa aagaagaaac aagtagagga gtagtaatag
     5221 ctcatgataa tagacacaag tctagacaat tctgtataga atctgcaaat actttggcag
     5281 catgtggtat aaaagcatat atatttgata gtttgagaac tactccagaa ttatcttttg
     5341 ctgttagaag cttaaatgca atcgctggta tagtcataac agcaagccat aatcctccag
     5401 aatataatgg atataaggta tactgggaag atggagcaca agttatgcca gagattgcaa
     5461 atgcaataac agagaaagta aatagtatac atgattatag tacaatacca accttaacgg
     5521 aagctaataa aaatttggta gttttgttgg acgaatcaca agatactaaa tttatagaag
     5581 cagtaaaaag ccaaattata agaaaagatt tagttaaaaa tgtaggtaaa agctttaaga
     5641 tagtttatac acctctttgt ggaacaggga atgttccaat aagaagagca ttgaaagaag
     5701 ttggttttga aaatataatt gtagttccag aagaagaaaa tccagaccca aattttgcag
     5761 ggcttgatta tccaaatcca gaagagaaaa aagctttaaa tagaggtata ttactcgcaa
     5821 aagaaaaagg agcagacctt gtaatagcaa ctgacccaga ttgtgataga gtaggtgtag
     5881 cagtaaaaac tactacaggt gagtatgctt tacttacagg aaatcaaatt ggtggtatgc
     5941 tgacacatta tataatagaa ggattaaaag aaaataacaa attaaaagaa aatcctacaa
     6001 taataaaaac catagttaca tcagaatttg gagcagatat agctaaagca aataatgttg
     6061 atgtattaaa tgttcttaca ggttttaaat ttattggtga aaaaataaaa ttatttgaac
     6121 aaaataaaaa tagaagttat gtatttggat atgaagaaag ttatggttac ttagttggga
     6181 ctcatgctag agataaagat ggtgtagttt cttcattgtt aatatctgaa atggcagcat
     6241 tttactattc aaaaggtata agtttatatg atggtttaat agaactttat aaaaagtatg
     6301 gatttttcaa agaacagact atatctttga ctttaaaagg tatagaaggt gtagaaaaga
     6361 taaaagaaat aatatcttat tttagagaaa atcaaattga ttatataaat agtattaaag
     6421 tagttgataa aaaagattat aaaaatggta tagataatct tcctaaatct aatgttttaa
     6481 aatacttttt ggaagatgaa tcttgggtag ctataagacc atctggaaca gaaccaaaac
     6541 ttaaatttta catagctgta aaaggagcta gtgatattga agcagataaa aagattcaag
     6601 gtttgaaaaa gtatatagat gacatggtcg aaaaattaaa ataaaatatt attattttat
     6661 aagataattt tgtaataata tttatttagc tgaaaattat aatttacttt cattgagtag
     6721 aatatggaaa tgttagtaga attgttattt tcagctttta tttgtgttat ttttacttaa
     6781 ataattatat tatagaatga atctgagtat aattaatatt gtataatgaa attaatttga
     6841 tagaaaaggg gatatttatg tttggtatag ataagaaatt gattgaatat ataattgcaa
     6901 aatccaatta cagtgaatta agttcaaagt cagcagaagt atctttcttc ttaatgttgt
     6961 ccatatttcc ttttttaata tttacaataa gttctatagc ttatataccg attcttcatt
     7021 taaataagta tatagctttg tttagaaata tgatgccaga aggtgctttt gctgtgttat
     7081 cttcaatcat agtttctgca atagacaata gaaacctgaa atttttagca gtcagttttg
     7141 tacttactat gtggacattt tcaagagcag taaaagctct tattaaagga atgaatagag
     7201 cctataaagt taaagaaact aggtcttttt ttaaaatttt atctatatca tttttattta
     7261 caataatgct tttggtcctt atttttttat ctatgatatt tttagtttac ggggaaaaaa
     7321 taggttattt tatttttaat cttgtaggat tggatgagat atttataaaa atatgggata
     7381 ttctaagata cactgtaggt ataataacaa taatagtgat atttacactt ttatataaat
     7441 acactccaaa taaaaagtta actattaaag aatctgcgcc aggtgctatt tttgctactt
     7501 ttgcttggtt tttagtatca tttttatatt cttattatac aaattactat gctaactatg
     7561 aagtaatcta tggaagtata gctgaaataa ttgtacttat gacctggatg tattttagta
     7621 gttggtctat cgttattggc tatgaggtaa attcaagatt gtattttaga aagataagac
     7681 atgaaatgtt aaagtaaagt atttaaaata aaagagagta tttagtatta taaatgtaat
     7741 tgaattaata aagaaatatt gacatttaag ttaaaaagtc tagaattttt ctgggctttt
     7801 tttattttta gtataacttg acaaatttta tttaatggga tagttttaat ttataatcat
     7861 ctttgaaaag atgactattg ataagtaagg tataaaattg gtaagtatca aaaaatatac
     7921 taaataaaaa ttatagtcct aatgagttaa tttctgtatt ttcaaataat gcagtattta
     7981 gtcatgtgtt tttatatgcg cctgtatttc caattaccaa tatattagaa taagctactg
     8041 taattagatt tagaaaaaag cgacataaat aattataaac
//
LOCUS       DAEQJM010000113         7920 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.116, whole genome shotgun sequence.
ACCESSION   DAEQJM010000113 DAEQJM010000000
VERSION     DAEQJM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7920
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.116"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..391)
                     /locus_tag="KRQ43_003460"
     CDS             complement(<1..391)
                     /locus_tag="KRQ43_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HBH2743794.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFKNSIK"
     gene            complement(686..1648)
                     /locus_tag="KRQ43_003461"
     CDS             complement(686..1648)
                     /locus_tag="KRQ43_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBH2743795.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            1839..2390
                     /locus_tag="KRQ43_003462"
     CDS             1839..2390
                     /locus_tag="KRQ43_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743796.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            complement(2928..3215)
                     /locus_tag="KRQ43_003463"
     CDS             complement(2928..3215)
                     /locus_tag="KRQ43_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743797.1"
                     /translation="MKKILYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVL
                     KTGYQNRATFYQDNYFNGEDKNDKIKFITIKIFIFLSLPLCFNILFNYLTS"
     repeat_region   3624..4578
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3823..3851
                     /rpt_unit_seq="atttacataccacatagttaatataaaac"
     gene            5225..6496
                     /locus_tag="KRQ43_003464"
     CDS             5225..6496
                     /locus_tag="KRQ43_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH2743798.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSIADTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPM
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     gene            complement(7135..7890)
                     /locus_tag="KRQ43_003465"
     CDS             complement(7135..7890)
                     /locus_tag="KRQ43_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1835 domain-containing protein"
                     /protein_id="HBH2743799.1"
                     /translation="MAHICFEDICYLLLKEAMKLKLIPHNKIVLFEDDLSIGNIFDVN
                     NYELRENIFKIRNVFENNPKLLFKPDLLEDRKLSKCRNIIIWCANNPKDLCGVYYVVS
                     KFQDKNIKIALVDEKKTEDALIRYSFTSEMSPEDFPFFLDKTLEIGFNEKLEFKNKWD
                     VLVKENSIFRALVGNEIKSVEETYFDKYILRNISDKWQPLIEVVANCMFEDEMRVKDW
                     FILWRLEKMASLKIVKIKGSKGDFYSDKEIRKV"
BASE COUNT         2942 a         1135 c          838 g         3005 t
ORIGIN      
        1 attttataga gttcttaaat gatattttaa agagttcaaa taaccctatt ttttcatatt
       61 ttatcgattt attaaaacaa ataattacag aggtaaattc aaaaaatgca taaaaagcta
      121 gtattataac tgatagtatt atcagaacta ttgacatggg attggtcaaa acttttataa
      181 aattatccat atttaggtag actatatgta aactttttat taaaatatca aatatatatc
      241 taatagatgg ccatataaaa aataaggcta atcctttatg aaataattca aataaaatta
      301 atgtactaaa attatatttt attataaaaa caagtttact taaaatattt ttacccgtaa
      361 atataaaatt tcttaaaatt ctcttttgca tgtttatctc cttgtatctg tttgttctaa
      421 ttttatcata tgttttaaat acatttagaa cattaatatg tattattcca agttatgatg
      481 tataaatgca aaaacacata ctctttttta ttgcatagct aatcatcaat atctatatag
      541 cttaatactt ataagtagga tactccatat ttacaaaata aaaaagtatc tcttttataa
      601 ctttcaaaaa tcacattgag atacttttta taatttaaat ctatatactt aatttaaaaa
      661 acattgcata actattgtgc tattattaca attcttcata taaatcagta cttaaatatt
      721 ttaaaccact atcattaaga gttaaaacta tattttttcc tttttcactg ctctttaaca
      781 acttaattgc tgcacacaca tttgcccctg aagaaaatcc tgcaaataca ccttctaatt
      841 tagctaattt tcttgctaca tcagttgcct cctcgtctgt aacttgaata taaccatcaa
      901 taagtttctt gtctactaat ggcaaatcca tagaatatcc tccaccttgt attttatgcc
      961 cttggtcagt tatttcttta cctgaataaa ttgctgctgt ttcaggttca acaacataac
     1021 atttgataga agaattatgt tttttaagtg tttttgaaca tcctgcaaaa gtactaccac
     1081 ttccaagaaa atctacaaat acatcaatat ttccatccaa ttgttcccac atttcttctg
     1141 ctgtatactt ttcatgtgca tgattacaag cttctaaatt aaattggtct gctctaaatg
     1201 catttctttc ttttgctatt ttttgagcct caatttctac aagtgccaaa tcttcaccag
     1261 atacctgtcc gtgaactgaa ttaggcattt ggtctacaag aactacttca gcacctaaag
     1321 ctttcatcat tcttgctctt tccatagaat ttccttttga catacacgct ataaatttat
     1381 atcctttaca tgcacaagct attgctagtc ctgttccagt attaccactt gttaattcca
     1441 caactgcttg acctggaact aataaacctg cattttctgc ttcggtaatc atttgtaatg
     1501 ctacacggtc ctttttacta aatcccggat ttaagtattc catctttgca taaatattac
     1561 cttgaactcc aaattcatct gctattttgg ataaatgtaa catatgagta ttgcctatag
     1621 cctctgtaac attattaagt acacgcatta caattccccc ttaatctctc aactatcatc
     1681 cgttgaaaaa caactcttta tgcagtataa tttatattac ggatgtacag tgtatttaac
     1741 gttcattata ttatacattt gtaaattata aataatgtta aataaattat acattcgtaa
     1801 attatatttg tcaataattt acattttaag gagttactat gagtattaat actgttattg
     1861 ctaaaaattt aaatagatta cgtaatgaac gtaacttaag tctaggtcaa cttgctgaat
     1921 tatctggcgt aagtaaagta atgctttcgc aaattgaaaa gggagactca aacccaacag
     1981 taaacacaat ttggaaaatt gcaagtggac taaatgttcc atatactgca atactggaac
     2041 aacctcaaaa tgaaactttt attgtatcaa aaactgatat agatgtacaa gtttcagaaa
     2101 ataaagatta tcgtctttat tgttattatc ccaatacacc aactagaaac ttcgaattat
     2161 ttcaaatgga attagaagaa ggtcatagtt atacatctgt tggtcattct gaaaaatcac
     2221 aggaatatat tatgattata gaaggtcaat taaaattaga agtaaatgac tctatttatc
     2281 aacttagaga aaatgactct atttgttttt cagctgaatc aattcataca taccataatc
     2341 aaggagaaaa aacattgaaa gcagtaataa taaattatta tccagtttag ccatgccatt
     2401 taataataga ataattattt tctatacaaa aagataaatc ctttgattag gatttatctt
     2461 ttttatttta tttttcttta taaattcatt atatagcttt acacttttat caattatgtt
     2521 ataataagct tatataaaag ttttatattt ttgacaaatg gagtacaaaa tactcctttt
     2581 tcttttttat tattgtgata attatttagt tagtattaaa atattatcac ttaaaacaaa
     2641 tacaaaacgt ctcttatatg tacatttttc attgttgtaa taatgatttg tgtatgtatt
     2701 tctcacaatt ggagtgctta tgcactcttt ttaaatacct ttattaccat aacctaaaag
     2761 ctattttatt atccctttta gtttattttt aagtagttaa ataaattatt ttatattttt
     2821 tcttcattta tatgaaactt ttgttttatc actatatgca ctttatattt aatataaaca
     2881 acacataatc ttacttttat cataacactc ctatatctaa atataattta agaagttaaa
     2941 taattgaata gtatattaaa acataatggt aatgacaaaa atataaaaat ctttatagtt
     3001 ataaatttta tcttatcatt tttatcctct ccattaaaat aattatcttg ataaaatgta
     3061 gctctatttt gataacctgt ttttaaaact ccattttgaa ttaacagcag tataaaaaag
     3121 attgctaata aaataaagtt ataatttttt tcttttaatc taaaattagc tataataaca
     3181 atgaaactat ataaagcata taaaattttt ttcataaaaa acacctaaat tctatatttg
     3241 tattttatat tgagccaaat ctaatttctg tatatttatt aagtgcagtt ctagttccta
     3301 ttgtagtagc attaaatatt ttttaatttt tatttttaaa ggacatctct ttatatttaa
     3361 attatagtat gaatattcat aaatttcaat ctatttataa gataattatt ttttatatct
     3421 aatatcttgt cattaagttt tattatatat atttataaac ttttcaatac tttttataat
     3481 tattctactt ttatatttta atcattaaaa ctaaagtcaa tgttatctgg taattattta
     3541 ctacaaatga taaaaaataa ttatatttta aagtagaaaa tgctgtataa attattgggg
     3601 tattttacct atacttgttg caaatttaca taccacgtag ttaatataaa acaaatttca
     3661 agcgattgga caacgaataa aaattgcaat ttatatatca tgtagttaat ataaagcata
     3721 tttgtgtcga tatatagttc taactaagta taagatttac atacctcata gttaatataa
     3781 aacaatgtgt ccgaattgga cacatagaaa ggaaaagtaa aaatttacat accacatagt
     3841 taatataaaa ctatgcttat atattatgtt tattctgttg tttctaaaat ttacatacca
     3901 catagttaat ataaaacgat tttttcatgc ggaggaaaat tgatgtgggg acatatttac
     3961 ataccacata gttaatataa aacagataat ctaggcacac atacaatgcg caaaacttta
     4021 tttacatacc acatagttaa tataaaacat tcagacgata taggcgcagg agctaagtat
     4081 tctgaaattt acataccaca tagttaatat aaaaccagca cgccaagtat aagtaaaact
     4141 tccactatca ccatttacat accacatagt taatataaaa ctaaatgttg ctccgtaacc
     4201 taaaaacata atgctccaat ttacatacca catagttaat ataaaacgtg aaagaaaaat
     4261 taatatgcta tttacatttt acaaatttac ataccacata gttaatataa aaccattcca
     4321 caatttatac aattttttct gttctaaaac atttacatac cacatagtta atataaaact
     4381 cttcttatct tccagttgca aaatctatgc ttgacctatt tacataccac atagttaata
     4441 taaaactagt ttgagtggta aaagtacgaa gtacccctct ttaatttaca taccacatag
     4501 ttaatataaa acatatgtaa ttcaccgttt taaattatag ataaattaaa tttacatacc
     4561 acatagttaa tataaaaccc caaaataaac taagtatttt cagtacttac acacatacaa
     4621 ctctctcaaa tttgcagtga accatgagta gtgcaattga taacatttat catacaccct
     4681 caatccctta cattgcaact gttaaaccct actttatcaa aaatatcgct cactgcaaaa
     4741 tttatatatt tttattatat cataaaattc aaactataaa attaaaatgg aataatttat
     4801 caatttaaga acacctacat atttgtaaat acttactata ttatctattc taataattct
     4861 tcttctagct ggaactaata taaaaatcat ctctgaaaga ttaggacata ctaatataaa
     4921 aataactatg aatagatatt ttcttgtttt aaacgatatg gataaaaaag cttttgaaaa
     4981 tataatcaaa gttctcttta aataacattc cattttatgt aagtaagcat tatatttttc
     5041 ttaaatgtca cttaagtgtc agttatatat aataatagta aacaactgta tttcactaat
     5101 atttgctatt atctaatagt atttatagtt tagatttgat ataatacatg tggtaaaatt
     5161 ttgatttgta aaacaaaatt ttacctacat atattaaaac aaatttaaaa ctaaggagac
     5221 ctatatgtta aaagtattaa aaggaaatat aatttttaca aaaacttcag aaactttcac
     5281 agtatttgaa aatagttata ttatactgga aaaaggtaaa gtaaagggaa tatttaaaga
     5341 gatacctaag gaatacaaaa acctaaaagt agtagattac actgataagc ttataatacc
     5401 tggtatgaat gacctccatg cccatgcctc tcaatttaaa aatcttggaa tggctatgga
     5461 taaagagctt ttgccatggc ttgaaactta tacatttcca gaagagtcaa attataaaga
     5521 tatagaatat gcaacaaaaa tgtataaaaa atttgtaaaa gaactttgga aatctggaac
     5581 tacaagaata gcagtgtttg caacagtaca taaagaagcc tctatgaaac ttatggatat
     5641 attcaaagaa gttggtcttg gagcatacgt tggtaaagta aatatgaata tgaattgccc
     5701 tgatacttta ttagaaaaca ctcaggattc tattgctgat acagaagaaa ttataaataa
     5761 gtatagtgat acagattcta ttgtaaaacc aataataaca cctagattta taccaagctg
     5821 tacaagtgaa cttttaaaag gtttaggaga tttatgttta aaatataata ttcctatgca
     5881 atcacactta tctgaaaatt atgatgagat tgaatgggtt agaagtctag aacctgaatc
     5941 taaattctat ggagatgcat ataatagata taatttattt ggtcaaactc ctactttaat
     6001 ggctcattgt gttcattgtt ctcaggatga aatagattta atgagagaaa acaatgttat
     6061 ggcagttcac tgtccagctt ctaactttaa tgttggtagt ggtgctatgc ctatcagaaa
     6121 attaatcgat aataatatta gattagcact tggatcagat ataagcggtg gacatacatt
     6181 gtcaatattt aaagcaatgg tatctgcaat acaattatct aaattatatt gggttaattc
     6241 tggtaagaag tataatttct tatctttatc tgaggctttt tatattgcaa ccaaaagtgg
     6301 tggaagtttc tttggaaaag ttggtagctt tgaagaaggt tatgattttg atgcattgat
     6361 tattgatgat tcaaatttaa atcatgacaa ttattctata cttgaaagac ttgaaagatt
     6421 tatctatgtt ggtgatgata gaaatatcat tcatagatat gtatgtggaa aactaattga
     6481 agaacctaat atataattat aataaaaatt ttaattatat attatggtta atttatgcaa
     6541 ctataattaa taaaagagta tattttaaat ctaaaagcta taggttgaaa catactcttt
     6601 ttattttgtt tatttatagc tttagttatt aatcatatat aaatctacaa aacgtattcc
     6661 tagtaactta tattttttga tatctacaat cataagacta tattattgga ttcatacctc
     6721 aaaaatattg ccttctgaac attattatat tcaaagttat gttaatttac aatgatatat
     6781 ctaacatgta ttgattaaaa aaaattaaaa cttgcttttc atctcctata tctaaagaag
     6841 tggcatttag aataaactat tgtaatatta aagttgaaat tttctagttt atttactcta
     6901 tagcaccata ttttaatact attaagtaaa aatgtagtta aaatatatac taatatccct
     6961 gaaataagta tttctttttt atttagcaca cttattcgta aggtattagt tattatattt
     7021 tcaaattata gaataaatat tatacttatt gctaattata atattaatac tgttaagata
     7081 tttttcttca tagttatacc cattatttaa tacaatttat tataaattca atttttaaac
     7141 ttttcttatc tccttatcag aataaaaatc ccctttactt ccttttattt ttactatttt
     7201 taaacttgcc atcttctcta atctccaaag tataaaccaa tcttttacac gcatttcatc
     7261 ttcaaacata cagtttgcaa ccacttcaat taaaggttgc catttgtcac tgatatttct
     7321 taatatatat ttatcaaaat aagtttcttc aacactttta atttcgttac ctactaatgc
     7381 tctaaaaata gaattttctt taactaacac atcccattta tttttaaatt ctagtttttc
     7441 attaaagcca atttctagtg tcttatctaa aaagaatgga aaatcttctg gagacatttc
     7501 actggtaaat gaatatctaa ttagagcatc ttctgtcttt ttttcatcta ctaatgcaat
     7561 ctttatattt ttatcttgaa acttactcac tacataatat actccacaca aatcttttgg
     7621 gttatttgca caccatatta ttatatttct acattttgat aatttcctat cttctaacaa
     7681 atctggcttg aataatagtt tcggattatt ttcaaaaaca tttctaatct taaaaatatt
     7741 ttctcttaat tcgtagttat ttacatcaaa aatattacct attgataaat catcttcaaa
     7801 taatacaatt ttattatgtg gtattaactt taacttcatt gcttctttta ataacaaata
     7861 acaaatatcc tcaaagcata tatgtgccat aaaattcacc tcttttaaaa ttaacaattt
//
LOCUS       DAEQJM010000114         7482 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.117, whole genome shotgun sequence.
ACCESSION   DAEQJM010000114 DAEQJM010000000
VERSION     DAEQJM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7482
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.117"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            200..643
                     /locus_tag="KRQ43_003466"
     CDS             200..643
                     /locus_tag="KRQ43_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH2743800.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            674..2491
                     /gene="ftsH"
                     /locus_tag="KRQ43_003467"
     CDS             674..2491
                     /gene="ftsH"
                     /locus_tag="KRQ43_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH2743801.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            2669..5371
                     /locus_tag="KRQ43_003468"
     CDS             2669..5371
                     /locus_tag="KRQ43_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HBH2743802.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEVITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSSKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            5405..6103
                     /locus_tag="KRQ43_003469"
     CDS             5405..6103
                     /locus_tag="KRQ43_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743803.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            6442..7398
                     /locus_tag="KRQ43_003470"
     CDS             6442..7398
                     /locus_tag="KRQ43_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HBH2743804.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFIGIIIFKIKKLL"
BASE COUNT         2986 a          803 c         1318 g         2375 t
ORIGIN      
        1 attttattaa aaatatcctg tataaaatta aatatcaata agataacaaa attccaattg
       61 aagttacaat attgtaattg acaataaata cttaatacta taatatttaa tacattaaac
      121 attatagtat taagtattta tttacagtat gcacttcagc ctaaatttga aataaagtat
      181 tttcgtaggg agcgtttgta tggatgagat gagttttaag aaagagctac tagagttgac
      241 tagagatata aatatgaaat ttacaacttt attaagtgat ttttatcagc cacttggtat
      301 tacagcagtg caagctttga ttttatctga gttatgtgaa catggagaga aaaaaataag
      361 cgatttaggg aagaacttaa acatgacaaa tagtaatgta tcagtaatct gtcaaaggct
      421 tgaaaaaaat ggctttttaa atcgcataag agatatagaa gaccaacgaa ttgtaaaagt
      481 aaaagttaca aataaatcat tggatataca agaacatatt tcaagtagta tttttgatag
      541 ttattttgaa aatatgacca gtgaaaaatt gcaagatatg gaagatataa tagaaggttt
      601 agagaaatta aataaacttt taacttacat tgattgcaaa taacataaaa ataatttaaa
      661 ggagaataaa attatggatg aacataaacc ccaaaaaagg tcagcactct attattatac
      721 agttataata atagtagtaa tgtttttaaa tgctttaata tttccaagtt taatggataa
      781 aaaaatggtt gagattgact atggaaagtt tctcacaatg ttggatacag gaaaggttaa
      841 atctgttgag atagaaaata atagaatagc aataaatcca tctagtagca aggataagaa
      901 tatatacata actggtagaa tggatgaccc agaattggta gatagactaa aaaatgcaaa
      961 agtagaattt actaaggtta ttcctaagga aaattcacct cttttaagta ttttacttac
     1021 atggataata cctataggta ttcttatgct atttggtaac ttaatgatga agtctatgca
     1081 aaagcgaatg ggtggtaatg ctatgcaatt tggaaaaagc aacgccaaaa tgtatgtatc
     1141 tgctcaaagt ggaaaaagat ttaatgatgt agctggtcaa gatgaggcaa aagaagcttt
     1201 aactgaaata gtagatttct tacacaatcc agaaaagtat aaaaagatag gagcacaaat
     1261 gcctaaagga gcacttttag taggacctcc aggtacagga aaaacactcc ttgcaaaagc
     1321 tgtagcaggt gaagcaaatg taccattttt ctcaatatct ggttctgagt ttgttgagat
     1381 gtttgtagga atgggagctt ctaggattcg tgatttattt aaacaagcaa aagaaaaagc
     1441 tccatgtata gtgtttatag atgagattga tactattggt aaaaagcgtg ataatggaag
     1501 tggattaggt ggaaatgatg aacgtgaaca aactttaaat cagttgttaa gtgagatgga
     1561 tggttttgat ggtggaattg gagtagtaat acttgctgct acaaatagac ctgacagtct
     1621 tgacaaagca ttacttcgtc caggaagatt tgatagacgt ataccagttg aacttccaga
     1681 ccttggagga cgtgaagcta tattaaaggt acatgctcaa aatgtaaatg taagctcaga
     1741 tatagattat aatgcaattg caaggtctac atcaggagca tcaggtgcag aacttgcaaa
     1801 tattgtaaac gaagcagcac ttttagcagt taagtctggc agagatatag tagaacaaca
     1861 ggattttgat gaatctgttg aaactgtaat tgctgggtat caacgtaaag gagctgtaat
     1921 ttcagataag gaaaagaaaa ttatagcata tcatgaaata ggtcatgcac ttgttgctgc
     1981 tatgcaaaaa cattctgcac ctgtccataa gattactata atacctagaa cttcaggagc
     2041 attgggatat actatgcaag ttgctgaaga tgagagtgta cttatgtcta aagaagaagc
     2101 aattgataaa ataactactt ttacaggtgg tcgtgctgct gaagaggtta tctttaacac
     2161 ttgtacatca ggagcatcaa atgatataga acaagctact aaaattgcaa gagctatggt
     2221 tactcgcctt ggtatgagtg aagagtttga tatggtcgct cttgaaactg taagcaatca
     2281 atatttagga ggagatactt ctcttgcttg ttcttccgac actgctgcta aaatagatga
     2341 agaggtattt aaaatagtaa aggcttgtca caaaaatgca attgaaatct tagaaaataa
     2401 tattgataaa ttgcatgaac ttgctaatta tttattagaa aaagaaacta ttacaggtga
     2461 tgagtttatg gaaatactta acttaaacta aaatgattat acacaagata aaaatgccta
     2521 ttgttaggca tttttatttt acaactaaat tttttaaatt catatttaaa tctttacata
     2581 atcttaatca ttaaaaatac atcttaacta caattttata tcggaattga tattataata
     2641 gtaatgaatg gtgtaaggag gttttttaat ggatagacct aatcctgata ttctattaga
     2701 aaaaattaaa aatgaagaag aaaaactaag tagaggtcaa ttaaaaatat tctttggtta
     2761 tgcagctgga gtaggaaaaa cctactctat gttggaatct gcacaaaatt taaaaaaagt
     2821 gggtgtagat gtagtagttg gatatattga accacacact agaccagaaa cattggctct
     2881 acttgatggc ttggaaattc ttcctgtaaa ggagatagaa tataaatcta taaaactaaa
     2941 agaatttgat ttagatgctg ctttagcaag aaaaccagaa gttatattag tagatgaatt
     3001 tgcccattct aatgttgctg ggttaaggca tacaaaaaga tggcaagata tagaagaatt
     3061 gctgttagca ggcataaatg tctacactac tgtaaatgta caacatttag aaagtctaaa
     3121 tgacattgtt gaggtaatta caaacgtatc agttaaagag actataccag ataagttttt
     3181 ggatacaaat acacagttag aacttataga tgttgaacct gatgtacttc ttgaaaggtt
     3241 caatgaaggt aagatatata agaaagaaca agctactaga gcaaaaaata atttttttat
     3301 aaaagataac ctggttgcac ttagagaaat cgcacttaga aaaacagcag agagagttaa
     3361 taaagaagtt caaatgacca gactatcaaa gggtgatgta actgtaatac ctacatcaga
     3421 tacacttctt gcatgtataa gtccatctcc atcttcagca aaagttatta gaactgcatc
     3481 cagaatatca gacagtacat ttgcaaaatg gatagcttta tatgttgaaa ctccaaacac
     3541 agcaagactt ccatttgatg aacaaaaaca actacaaaat aacctaaaat tagctaagaa
     3601 attaggtgga gaaataattg ttttacatgg tgaaaatata atagagcaaa tacttagaat
     3661 tgcaaaactg agaaatgtaa caaaaattgt aataggtaga aatcattcaa gtaataaaag
     3721 atttagtaaa agatttaaaa aagatatagt tgacaaatta attgatgaag ttgattatat
     3781 agatatacat ataattccat ataaatttgc ctcagatgtt aaatacaaac ctaaaaagga
     3841 taaatcatca ataaaatcta aatttaaaat tagcaaagtt gattttataa aacttatatt
     3901 tattactttg atgataagta ttttagcata tgcagtacaa agcatgggat ttataagaga
     3961 aaatatattg ttaatatata tgttgggtgt agttttagtt tctatgtgga ctaaagggta
     4021 tagtacaggt ataataagtt ctgtatttaa tatagttctt ttaaattatt tttttacagc
     4081 accattatat acattatcta tagcagattc aaactatata gtaacactgg ttgtattctc
     4141 aatagtaggt ataataacta gcactcttac gtctaagata cagcatgaag cagaaactgc
     4201 tgctaaaaga gaagaaaata caaaaatgat atatcaaata attaagggat ttttaagatt
     4261 atcaagtaaa gatgatatag taaacaaagg tatagaactt ttgtctctta gcttaagtag
     4321 agatgtaatt tgttatttaa atgtagataa gcataataaa tcaaaacttt acaaaaaaaa
     4381 tactaataat aaggataaaa atgatttgga tagtgaagat gaaaaagctg ttgcaagttg
     4441 ggttttatcc aattcaacag tggcaggaaa tgacacggat acacttcctg gttcaaaggg
     4501 atactatata ccaattgtag gaatgaattt aactttagga gtagtaggaa tatcatgtat
     4561 tgattcaaaa ttggatacag aagatataag cttaattgaa acaataattg ctcaaatggc
     4621 aatagcgctt gatagagaaa tcttgtcaga agctaaagaa aataccaatc ttgagattga
     4681 aagggaaaga ttaagaagta atcttttaag agcagtttcg catgacctta gaactccact
     4741 agcaggaata tctggtgcag taagtacaat tataaaaaac aagggtacta taggtcaaga
     4801 tataatagat gaattactta gtggtgtata tgaagatact cagtggttaa taagacttgt
     4861 tgaaaattta cttagtatga ccaagataga tgaagggaaa ttggaagtta aaaaacattc
     4921 tgaactggtt gaggaaatta tatcagaagc gttacaaaaa ataaaaaaaa gaattgaaaa
     4981 tgcacttata gatattaata taccagaaca gatattattt gttcctatgg atgcaaaatt
     5041 aatagaacaa gttttaatta atttaataga taattctttg aaatattcaa aggaagattg
     5101 taagatagag ataaatgtat acgagaaaga tgattatgtt tggtttgaag tatctgataa
     5161 tggtcctggt atatcaaagg aacttaaaaa gcatatcttt gacagatttt ttactggaga
     5221 agaaggagct aaagattcca gaaagggtgt tggacttgga ttatcaattt gtaaatctat
     5281 aattcaagct cataaaggtg aaattatggt agaaaacaat aaagataagg gttcaacttt
     5341 taagtttagt ttgcctaagg aaaatgaata gttttaaatt ttaaaattag ttttggagga
     5401 agaaatgagt aaaaaactta tattgttagt agaggatgat aagacaataa gaaaatttat
     5461 atctactgca cttttaacac aggattatga tgtcaaggag gctataactg gaaaagaagg
     5521 tatatctatt gctgtctcat attctccaga tgttgttctt ttagatttag gcttagaaga
     5581 tatggatgga atagaggtaa taaaagctat cagacaattt tcaaatatac caataattgt
     5641 agtttcagct agagagcaag atagagataa ggtagaagta tttgatgcag gggcagatga
     5701 ttacttaaca aaaccattct ccatagtaga gttattagca agagtaagag tcgcatttag
     5761 acattcacaa gtagaagctc aacaaaaaga tgatgttaaa tctacgtttg aagtagataa
     5821 attattgatt gattttgata aaagaaaagt tattgttgat gatgttgaag tccatttgac
     5881 acctattgaa tataatattc tttcattact tgcaaagcat catggaaaag tgcttactca
     5941 taattttata ataaaagaaa tatggggtag tgttataggg aatgagacta agtctttaag
     6001 ggtctttatg gcaacattaa gacgaaaaat agaaaaacaa cctgcaaacc caagatatat
     6061 aattacagaa gttggtgtag gatacagatt aaatgatgaa tagttgtaat atattaatta
     6121 ttagattatg tgcttattaa tatatattaa aattatatag tttagttaaa ataagaatga
     6181 agtgtatgtg cttgttgtca gtttagcaca tgcattttat tttttagctt tttagtatca
     6241 ataatatgaa atatgtttta aaataagtat atagtgtaat ctgtaataaa aactttggtt
     6301 aaataataaa tgtatttaac acttacctta taataaattt aatgtaaata ttaaataata
     6361 attgttaaaa tagtgtaaaa taattacagt aaggattata aaaaattttt agaatgtaaa
     6421 ttgaaattta ggagtagatg tatgtatata ctgaatttaa atacaagaga gactattgaa
     6481 gattttagag ataaatttta tgtagcagaa aattcttatc ttatattaag tgctccaaaa
     6541 aatttaaaat tgcttaagga aactttggat atagatgaaa taacttttaa tgattgtctt
     6601 aaatttgatg aaataaccaa acttgattta tttgataatt acgatttttt aagcctaaat
     6661 acatttgaac taagagatgg agaagctgtt atagaagaag taaatatgta tttatcagat
     6721 aattttatat tggttgtagt gaatgaagaa cactttttat ttgaatttgt aaaaaatatt
     6781 attttgaaga actctcaact tgaaaaaaat ccagttatta atctatttaa gataaactac
     6841 ttgattctta gagaagttat aaaaaatggt tttgagtctt tggaaaaagt tgaagagtta
     6901 attcttcaaa tagaagatga aatgatggac aacattaata agaatcatgt atctagaata
     6961 agtgatgtaa gaggattaac aagaattata gttaagaata ctagacctct tttgtatatt
     7021 ggggatagaa tagttaagga aaatataaga tatttaaaat attcaaatgt aaaaaaatat
     7081 aatttagaaa attttcaagg tatagatttt ggaattgaca aattatacaa tttcgcattg
     7141 tcaacacgag agttagcaga taaattatta gatatttatt cttccagagt aggtgagaaa
     7201 acaaataact taattacaaa attaaccttg ttaacagcca tatcagcacc acttacaatt
     7261 ataactggta tatatggaat gaactttaga tatatgccag aattaaactg gatttatgga
     7321 tatccagcaa ctttattttt tatgctatgt ataattttta ttggaattat aatatttaaa
     7381 ataaaaaaat tattgtaaat tacagatgat gtttaattga ttttataaaa atacatcaat
     7441 tgagaagctg atttaagtaa ataaaaaaat attttaaatt ga
//
LOCUS       DAEQJM010000115         7231 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.118, whole genome shotgun sequence.
ACCESSION   DAEQJM010000115 DAEQJM010000000
VERSION     DAEQJM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7231
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.118"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     repeat_region   422..1108
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=488..516
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            complement(1500..3233)
                     /locus_tag="KRQ43_003471"
     CDS             complement(1500..3233)
                     /locus_tag="KRQ43_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH2743805.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDVFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     gene            complement(3473..4318)
                     /locus_tag="KRQ43_003472"
     CDS             complement(3473..4318)
                     /locus_tag="KRQ43_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH2743806.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            complement(4349..6583)
                     /locus_tag="KRQ43_003473"
     CDS             complement(4349..6583)
                     /locus_tag="KRQ43_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH2743807.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQYIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESSRELKIRLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLILFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
BASE COUNT         2510 a          941 c          881 g         2899 t
ORIGIN      
        1 aaaaaagtac taatgagtta cactagtact ttataactac ttttacatgt tttaactgta
       61 taaaacagtg ggtatagttc agcaggagtg actttagttt tgaactaaaa atcaagttca
      121 aaaagaataa acattagtat ttgaacttca ctctacgtct aaatagattg tagttcttct
      181 tgtttttatt ataccacaaa ttggtacaga tattcaaaaa taatatattt atgatataat
      241 aaaaatgtaa atagttttgc agtgagcgat atttgttaca aagtagggct taatgcttga
      301 aatataaggt gttgagggta tatgataaac tttatcattt gcactactca tggttcactg
      361 caaatttaag agagttgcac atgtgtaagt attgaaaatg cccagtttat tttggggtaa
      421 agttttatat taactaagtg gtatggaaag aggtttttca gaagtatatg tacgtctata
      481 ttgtaaagtt ttatattaac taagtggtat gtaaataagg aaggtggaag tcaatatgca
      541 tgggtcaaat gggttttata ttaactaagt ggtatgtaaa tacgaaatta gagtttgaaa
      601 tatatgacta cataatagtt ttatattaac taagtggtat gtaaatttgt gtcacatcat
      661 tgtcacttct ttagaatatc aaaagtttta tattaactaa gtggtatgta aatttttaag
      721 caggtgatta aatgattaaa aaagtagaaa agttttatat taactaagtg gtatgtaaat
      781 aataacttgt caatgtagtt atatgcaaca acttctatgt tttatattaa ctaagtggta
      841 tgtaaatgaa ttatatatta tgaaaaaata tggagtcaca gagggtttta tattaactaa
      901 gtggtatgta aatttgcagg ttttccttat agtttgccat atgttcctgg ttttatatta
      961 actaagtggt atgtaaatta ctttagcact agtaaaggta gaattattaa agtgttttat
     1021 attaactaag tggtatgtaa attcgaatgt gaatggcact tctatttctc caacttttgg
     1081 ttttatatta actaagtggt atgtaaatag tataatgttg aaaagttaga gagtacaatc
     1141 aagaaatttt acattaacta aaatgtatag aataaaacat gtatttatac ttaaattctg
     1201 tacctatata aaaaagtgaa ctctgtcaac aaagcacttt tttatataga taaattatca
     1261 ttttatttta agatagaaga tactaatgct aaatgtttat cattagtatc tgtatgtaca
     1321 taaaagttta attttttata taaatttgat ctttagaaaa atgagcagta tcaataaata
     1381 tattgtctaa attttttcta ggaactagtt gactagctat aagattagct tcaactcttt
     1441 gattgttaga ctatgaaatt aaatctaaag gttcattctt ggtcgtataa atagctttat
     1501 cattcgtatg tactataaca atttttgcca tctgcttttg atagataaag agctttatca
     1561 gctttagaaa ataaatcttt atataattta gttgaatcat cagtgaaggc aataccaata
     1621 cttaatgtta ttttatgatt gtcctttact tttattttac ttgcatcatt taaaatatca
     1681 ttagtaattt ttattattaa atcctttgtt aatgatttta taaatattgt aaattcatct
     1741 ccaccaattc gagcaactat gtctttatca tgtgtgttat gtaatagtat ttttgataca
     1801 gcaactaaaa cttcatttcc ctctaaatgc ccaaaagtat catttacagt tttaaaatca
     1861 tcaatatcaa taactaatag agcatcatta tttttggaat cagaactaca tagatactct
     1921 tcaataagat tttgtgatac tctttgatta tataattgtg ttagtgggtc acgttgagcc
     1981 tgattaatta agctttctaa tttagattta tcttcagtta tgtcttttaa aacgcctatt
     2041 gttttgatag ggttatggtc actatcatat ataactgaac attgaacacg aatccatctc
     2101 cattcatttt tagttaatga atttacttgt cttatctcaa ttgtttcacg aagatttcca
     2161 tgaagtactt ctagtagttt tccaatatca tcaaggtgaa taattttacc agattctaat
     2221 agtttggagt aattttttgt ttcaaaattt tctaattcaa tttttttgtc aatttctaca
     2281 cgttgatatt ttataagggt atcgttttca atatcatact caaacatgat atctgtaata
     2341 ttttgcaaag caatacgata tcgctctctt tctaatttta gttcagattc tatgtttttt
     2401 agttgggtta tgtcagtaat aatactatta atttttacta tgccatcact atttaacgat
     2461 ttcattccag aatctaatac ccacattaat gttccatctt tttttcggat tctatattca
     2521 gatgaatatg taggtccttt tgcaaaacat cgttcacaat cttctagtgc tttaggtaag
     2581 tctggtggat atacagcacc cactgctgaa ccaccactca tttccatgaa ctcatcatat
     2641 gtgtatccta atattttggg caatccctca ttgacataga aaaatgagta tgtactatca
     2701 tcattgctac cttttaagcc accattgata ttatttgtaa tcatttcaat aacttctgtt
     2761 ttttccttta gtaatctttg caaataatca taactttgag ttccaatttt agtgggaaag
     2821 tattcatcaa gttgcatttc accataaggg tttgatatgt gcatgtgctt tactaataat
     2881 tttcctctat cctcaattat ctcaaatgta caacgttgat ttacctctaa aatcatttga
     2941 gcattttctt tagttcgaac agtatatctt cctaatacca tacatctatt ctcatcttca
     3001 cttacagttt caaatacatc attatttata tcacaagaag gaatttcatc ttgacctgca
     3061 taaaaataat tttttatttc attaaaagaa gtgagaaatt cctgttctcc tggtccaatc
     3121 catgtaacat tttcacaaag gtattttaat acttcattga tatctcgatt tatataaaaa
     3181 cttgttataa tatgttttgc taatttgggt gcttttttta ggagtatgct catgatattc
     3241 ctcctttctt tttgctatta tattttaatt atattataca tcaatatatt taaattaaaa
     3301 gctttgttaa actatgatat ctttgtcaaa taagttaatt ttaacaaaaa agaactgaaa
     3361 caatatatgc ttcagtactt aatgtcaata tcttgtatag atacatattt ataaactaat
     3421 gtacaagttt aaaaaaagaa agataatttt aatttatttt aaaataacaa tgttaataat
     3481 catttttatc aaattttttc ttgtttttct ccttgttttt atacattttt ttatccaatt
     3541 caactattgt caattttaaa tttcttttta ctgtatcaac accataacta aatgaaagat
     3601 acttatattt agagaatact tttaaaaaat tttctcttaa ggcttctagt tgtgaataaa
     3661 cataattttt gtcaacatca ctagagaata taacaataaa ttcatctcct cctaatctta
     3721 taatagaagt agaatttatt aattctttat ttaaaagtga aacaaaatca cataaaatct
     3781 tgtctcctac attatgacct tcatagtcat ttatcatttt gaaattatct aagtcaatta
     3841 gtacaatata atctcctata aatatgtcaa atctatcatt taaatatttt ctattatatg
     3901 ctccagttaa tgggtcagta attgagtagt gaagatttct cttattttct tcatagagtt
     3961 ttgttatatc attggccata gtaattatgt aggttttttc atcaacatct actttgtatt
     4021 ctaaaacatt ccaatagctt gtagtatctt ttttaaactc taaaatccaa tttgaaattt
     4081 tatcataagg ataatttttt tcccaatcta attgaatatt gtgagaatcc gtaaaaaatt
     4141 tagcaatatt atcagggagt ttcttagcta tttctatatt agtcattcca agtggattat
     4201 cttgcatata acttttaatt aaatttttta aattatcatt tataaatata attctgtagt
     4261 tagaatctct tataattaga aatcctggaa aagttcttaa aaaaatttct ttaaacatat
     4321 taatttctcc aaaataaaat actttgtact agatttttgt taaatttttt attttattta
     4381 catctacata cataccttgg gcaatcgacc ttccatcaat tgcagaaagg ttacattgtg
     4441 tatacataac tgtgacaatt tgaccatctc gttttatgaa tctatataaa aatggttcaa
     4501 ttttatttgt gtcaatcata tccaaacttt ttttataaac aaagtctaaa tcatctggat
     4561 gaacaattgc tcttaaattt ccgcccatct caccaaaaaa ctgttctttt gtataaccta
     4621 taatgtcaaa catttcttca ttcatataag taataatcat atcaccaaat aaatcgtagc
     4681 gaattatacc tacaggcaac attgaataaa attgtgataa aatattactt tcatcaagat
     4741 gtgtatttgt cattttaggt attgaatatg attcaaattc atttatatag ccagcagttt
     4801 taattaaatc caaatgtaat tttgctaaga gtaatttatt ttctgaaatt atacaatttg
     4861 cactaaagta gaaattgcta tatttttgat gttcagaagc ttcatctgat aaaacggctt
     4921 ctccactaat taataatgaa tctgattcag tattatgtgg ggttatactt ttgtaaagaa
     4981 tagaaaattt tttaccttta atatgttttt caaaatgttc tattacttta ggaaaagatg
     5041 taatttcagt tttgttgtaa aaatcaaacc attgaatgtc ttcagtgaca ttagctctta
     5101 gttttttcat atcttgcata ataaaaaatc catcaaatat cttctctatt aaagattttc
     5161 ctatatcaga atattttata aacattttct ctgaattatt ctctttagat agtaattttt
     5221 caaattcttt gcactccatg ggttttgcat aataataacc ttgggcgata tcacaattta
     5281 tacttttaat aaattctaca tgttgttctg tttcaacacc ttcacatact gtaagcatcc
     5341 caagagctct tgcaatgttt attatagagt acaaaatggt tgtattttta aaatcattta
     5401 aattatgaga taaaaatatc ctatcaattt tgattatatc aaaaggtaga ttttgcaaca
     5461 taccaaaaga tgaatatcca gaaccaaaat cgtccattga tacagaaaaa ccataagaac
     5521 gaagttcagc tagttgttga ataattgtat ttgtattttc tattaatata ttttctgtta
     5581 tttcaatgct aaaatttgat gtagagacgc tgtacttttc agtaatacct tttagcatac
     5641 ttggaaaatt agggttaaaa aaatgaagac gagaaaagtt acaacaaatt ggaacaaaaa
     5701 catcattgtt atcaatccat cttcttatat ttttacagtt ctcttcaaat aaatgcaaat
     5761 ctaattccgt tatcagacca aactgttcaa ataaaggaat aaatttatct ggagtaagaa
     5821 gtcctttaat agggtgtctc catcttgcaa gtgcctcaca tccaactata gtattatttt
     5881 ttatattata aagtggttgg taaaatactt caatttgttt agtttgtaga acatgtgata
     5941 tttctgataa gaactcctta tcattttcta atttattgta aaaactatta tctttaaaat
     6001 caaatagaat gtatctattt ttgccttcac ttttagcctt ttttaaagca ctatatactt
     6061 ggttgaaaag tatcaaagta gtcatgtttg gttcaccatt ccagatagtg ctgccgatac
     6121 taaatgtaac attggagtat atttcttttt cattaggaag tcttattttt aattctcggg
     6181 agctctctat aatagttgca cccatattat ttaactcttt atttgataca tttggaagta
     6241 caattaaaaa accttctcct tttaaataag cgactattcc ctttgattct ggaataaagt
     6301 gcaataggtt ttgagttaga gtaattaata aattttctcc gactagatat ccatatatat
     6361 cattaaataa tttaaagtta tcgatattta ataacatgat tcctatatgt atatttttcg
     6421 aaatacagtc atcaatatat tggtacataa attctctgtt tggtatttta gaaaaaaaat
     6481 ctatttcatt taaggttttt aatttaaaat ttctactatc taattcctta gataatactt
     6541 ctaccttttt atttaacatt tttatataat tatgattttg catggtattc ctccataaga
     6601 tactttaaat tttgatgaca actgtattta tgctagaagt atttaaatgt taatttgtaa
     6661 ataatttaaa tgctaaattt taaataagta tttaaaatga atatacatta agttatttgc
     6721 tccaatgcta caaatacaaa tattttttag tttagtaata atattagata aaattagtta
     6781 atgcttaaat tatagtatat tgaaagattt cctttttgaa tgcaattata tcatattttt
     6841 tcataaatag atagattgtg agctgtatag ttagtaaggt agagtttttt tataattaat
     6901 tttaagttta atgatttttc aaaggcataa ttattttatt cataattaac tttttataca
     6961 taatttaata ccacataatt aattttagtt attaaaatta agtttattct tgtatttttt
     7021 gttaaagact ataataaata ttcatttact aaatttataa actattaatc tatagaaatc
     7081 agttttaata tgaaaaatat tacatagaga tggatataat agctgtaaac ataaaactat
     7141 ataaaactaa aatatattta taaaaaagtt gaagttataa atactatacc taacattaca
     7201 atataaaaat attttaataa ttaattatta g
//
LOCUS       DAEQJM010000116         7131 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.119, whole genome shotgun sequence.
ACCESSION   DAEQJM010000116 DAEQJM010000000
VERSION     DAEQJM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7131
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.119"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            285..1136
                     /locus_tag="KRQ43_003474"
     CDS             285..1136
                     /locus_tag="KRQ43_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH2743808.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            1140..1610
                     /locus_tag="KRQ43_003475"
     CDS             1140..1610
                     /locus_tag="KRQ43_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743809.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            1623..2933
                     /locus_tag="KRQ43_003476"
     CDS             1623..2933
                     /locus_tag="KRQ43_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH2743810.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            3145..3891
                     /locus_tag="KRQ43_003477"
     CDS             3145..3891
                     /locus_tag="KRQ43_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH2743811.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCNSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDDGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            4253..5794
                     /locus_tag="KRQ43_003478"
     CDS             4253..5794
                     /locus_tag="KRQ43_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH2743812.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            5829..6935
                     /locus_tag="KRQ43_003479"
     CDS             5829..6935
                     /locus_tag="KRQ43_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH2743813.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVTTEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DPLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHSMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
BASE COUNT         2527 a          947 c         1218 g         2439 t
ORIGIN      
        1 tattactaat tttaaagctt tttagctatt attcctacaa tatttaaaca attttttcat
       61 aataaagcta tattacaata tattcaaaat atgtaatatt ttagatattt ttcgttgaca
      121 atgttaaatt tttgttttat ccttaattaa ggacatgtta ttgacatttc tgaaacttat
      181 ttgaaatagt tttttcattt tatttaggaa aacgtattat acttaagaaa acgtattttc
      241 tcatttcaga taagtaaaat atttattctt ttggggagga aatcatggaa attaataaaa
      301 aacattttat tcaagtattt ttaacttgct taatcttggt agtaatatgt gaatttatag
      361 ggcaaagaac tatagctatt ggaaaagcct ctatagtact gttccctatg ctttatgcag
      421 ttataattgg acttataata acaccagatt tattaggtaa aaaaattaaa gcacttaaaa
      481 aagtggttgg agaaaaagaa ataaatattg ctggtgaagt tgttggaatt gcactagtaa
      541 tgcttggtat aaaatatggt actacagttg gaccaaacat tgacaaaata attcaagctg
      601 gaccagcatt tatcgctcaa gaatttggtc atatacttgc accaatcgtt gcattacctc
      661 ttgcattaat gtttggaatg aaaagagaag ctgttggagc tactgcaagt ataagtcgtg
      721 aaccttcttt aggagttata tcagaaaaat atgggataaa ctcaccagaa ggtagtggtg
      781 tacttggtac atatttaatg ggaacagttc ttggtactat atactttagt gtactaggtt
      841 caatatctat ttatagtggt cttcacccat atgctttggg aatggcctgt ggtgttggta
      901 gtggaagtat gatgacagca gctgctggtt cattatctac catggtacca cctgaaatgg
      961 cagatacaat acttgcctat gctgcaacaa gcaatatgat gtctagtata acaggaatta
     1021 tattcttagt ttttgtatcc ttaccattta ctaattttat gtataagatt ttagaaccta
     1081 aattttcgag aaataaaaaa actaaagaaa ttaaatctac agaaggagag tgctaataaa
     1141 tgtttgctaa tttaaattta aagaaaagtt catatcaatt attggttatg tctgttattg
     1201 gagttataat tcttatagga caaagaatta gcgttggtac atctatagtt acagctcttc
     1261 ctggtatggt gatgctaata ttagctgcta tggcagctat gattataaaa gatttatttc
     1321 ctaaatcaat ctttccagct tttggatttg caactataat cggcctttta cttagtatgc
     1381 catatagtcc aacatctgaa gtattcttaa ctaacactaa taatattaac tttatggcta
     1441 taactactcc actactagct tttgcaggaa tttctgttgg aaacaaaata gaagctttaa
     1501 aagaaatgtc atggaaaata gttataattt cacttattgt atttacaact atattctttg
     1561 catgtgcgag tatagctcat atagttttaa gtattcaagg taaaatatag gaggaattta
     1621 ttatgaataa agaacaatta aaatctctag taataaaaac tatagatgaa aatagagaaa
     1681 aaatattaaa aataggtcaa ggaatataca aaaatccaga atatggatat aaagaattta
     1741 aaactacaga agctgtttca aacttttttg agcaagaatt aaatttatct gtagaaaaaa
     1801 atatagcagt tacaggatgc aaagcagatg caaattctag caagaaaggt cctcatatat
     1861 ctatacttgg agaattggat ggtatatcat gtaaagaaca taaagatgct aatgaaatag
     1921 gtgcttctca tacttgtgga cataatattc aaatagctgg aatgttaggt gctgctgttg
     1981 gtttagtaaa aagtggcgtt ttagaacatt tagatggtaa agtatctttt atggctactc
     2041 ctgctgaaga gtttattgag ttggaataca gagagcaatt aaaaaaagaa ggaaaaataa
     2101 cttattttgg tggaaaacaa gaattaataa aaagaggtta ttttgatgat atagacatat
     2161 ctatgatgtt tcatgcttct gatttaggag aagataaggc tctagttggt cctgagagta
     2221 atggatttgt tggaaaaaag gttaaattta taggtaaaga atctcatgct ggttctgctc
     2281 cacatgatgg aataaatgct ttaaatgcag caatgcttgc tataaacaac gtgaatgcac
     2341 ttagagaaac ttttaaagag tctgaaagag ttagattcca ccctatcatc acaaaaggtg
     2401 gagatatagt aaatgttgtt cctgctgatg ttcatatgga atcatatgtt agagctagaa
     2461 ctataaatgg tatgattgat gctaatgaaa gaataaataa ggctttgatg gctggtggaa
     2521 tggcagttgg agctgatgtt gagataactg aaattcctgg atatcttcca atattacgat
     2581 acaaaagtct tgataattta tttaaaaaca atcttgaaga tttaggtcta aaaggaaaag
     2641 ttattgatgg tggagatttt acaggctctt ttgattttgg agatgtgtct catataatgc
     2701 ctactcttca ccctatgatt ggtggtgtaa aaggagctct tcatacaaga gattttgaaa
     2761 tagttgatga agatttagct tacataattc ctgctaaagc aatggcactt acagttgtag
     2821 accttctttt tgataatgct aaggatgcta aagatatatt agataccttt actccagtta
     2881 tgactaaaga agaatatcta acattcctag aaaaacacga taaaacttta taagtctatt
     2941 tttataatag ggtggtatct actgtaaaag ttataccact ctttgttttt gtaacagtat
     3001 acttcttttc ttttagcttt tagattaaac taaaatatat tatcctcctt aaaactttta
     3061 gagatacgtt aaaatatcag tagaactatg ctatattctt tctaattaat ataaatttat
     3121 attctaattc aaggtggtga aaaaatgttt aatgcaggaa atcgaattat aaatacatgg
     3181 ttgtacccta ttcaagatgg ctttgtcttg attgatactg gatatgaaaa tggttttaaa
     3241 catttcaaaa aacgaatttc taaattcaac ataaaaatca aagatattcg atacatattt
     3301 ctaactcatg ctcatgatga ccatgttggt tttctaaatc agattctaga cgaatctcct
     3361 aatacaaaga ttgttatgca tgataaagct ttagaaattc tatataaagg tcaaaactct
     3421 tttattggtg gttgtaacag ccgtactgcc tttctctttt gccaaattat gaaactattt
     3481 ggaaaaggtg agcatagttt ttctccactt aaacaagaat ttgaaaaaag gtgtattctt
     3541 gtgtctgaca agaatcgtaa agaaattgaa aaagaactaa atggaaaaat tatagataca
     3601 ccaggacata ctgctgattc aatttcacta ctaattgatg atggtgtttt attttgtgga
     3661 gattctgcaa tgaatggatt tccaagtact cacaaaatta ccatatttgc agaaagcaaa
     3721 ctagaattta ttcaatcttg gaaaacaatc atcaatacaa aacctaaaat gatttatcct
     3781 ggacatggaa aaccatttga atacagtaaa ttagaacaaa atctaatcta tgtaaataaa
     3841 ataaatttat atcctctaca taattcaaaa gatattcaca gatttttgta gaaaatacaa
     3901 agtaaatttc tttgattaat taaaaaatct aacactttac tacgctactt attttaataa
     3961 cttaatcttc cactagcttt tcataaaatt ttgttttaaa attaacttta aagtgcatat
     4021 gctatttaaa tacattagat ataattcgtc attaatctac ttaaagcata tttaactaac
     4081 accactcaac cagaaaattc agaaaactgc attgacacag gaaaaagttt attttatact
     4141 ttttttagga catattgtgg acacgtctta aatcgacaag cagaatttat attgtaagat
     4201 caaccacaat acttattttt taattatatt tttaaacatt agggaggata ttatgaatga
     4261 taacgtagtt aagaagaaaa acttttttga caggacatta aacagaatag aaactgttgg
     4321 taataaacta ccagacccag ttacaatatt tttagggtta tgtgtacttt tacttatact
     4381 atctagtcta gttggttcta tggggatatc agtagttcat cctggtactg gagaaactat
     4441 aactgcagta aatttattga ctgtagaaca gcttcaaatt cttttaggaa acatagttag
     4501 caatttccaa gggtttgctc ctttgggtct agttctagta actatgatag gtgctggtgt
     4561 atgtgacaaa acaggactta tgacagcaac aatcaaagca tcagtaagca agattcctga
     4621 aacaagagta actcttgttg taatgactat aggtatgctt gccaatatag cttcagatgc
     4681 aggtacaata ttatttccac cattagctgc acttgtatat cttggtgttg gtagacatcc
     4741 acttataggt ttattttctg gatatgcagc agtctgtcta ggatttgccg caaacattat
     4801 gataagtgtc aatgatatac ttgctgcaag ttttacagtt ccagcagctc aaatgattga
     4861 ttctggattt caagccaatg caacaatgaa cttatttttt atgatagcat caacttttgt
     4921 tctaatactt ttggcaacat gggtaacaga aaaaattgta gctcctagat ttggtaaata
     4981 tgaaggaaat gcagaactag atgttgatgg aagtcttagt gatgtagaaa agaaagggct
     5041 taaaaaagct ggtataagta tattaatata tgtagctatt atagtagctc ttagtgtaat
     5101 cggtaaaaaa ccattcttag ctgacccaga aacaggagat ttactatcaa acaatgctcc
     5161 tcttatgaaa ggtatggtac ctataatagc actagcattt ttcatacctg gtgttgtata
     5221 cggaaaaact ataggtaaaa taaagaagga taaggatgta gtctctataa tggctagtgc
     5281 aatgagtgat atgggtggat atataatact agcatttgct gcttcacaat ttttgcaatt
     5341 attcacaaat agtaatttag gtctgatact agctgtaaag ggcggagaat ttttaaaatc
     5401 agcaggaata aatggacctt tattgttgat aggatttatt atattatcat gttttataaa
     5461 tttatttata ggtagtgcat ctgcaaagtg ggctattctt gcacctatat ttgtaccaat
     5521 gtttatgatg gttggataca atccagcact tactcagatg gcttatcgta taggtgattg
     5581 tataacaaat ccacttagcc cattatttcc gtacttccct attatactag cattcacaag
     5641 aaaatacgat aaagatgctg gtatgggtac tgtaattgct aatatgatac catactctat
     5701 atcattctta atagtgtgga ctatactatt aatattgttt atggtattta atattccact
     5761 aggacctgga atacttcctt catatagcat gtaatttatt taaatctttc taaaaggaga
     5821 aataatttat gttagataaa aatagactta taaataattt tatggatatg gttagaattg
     5881 atagcccatc taatcaagaa ttagaaatgt ctaagtggtt ggtaaactac ttaaaagaaa
     5941 gaaatataga tgccattata gatgatgcag gtgaaaaata tggtggtaat acaggtaatg
     6001 tcattgccta tataaaaggt gaagaaggaa gtagaccact ttgtttatgt gcacacatgg
     6061 accaagttca accttgttta ggtgtaaaac caatactaga tggtaatgta gttagaagtg
     6121 atggaactac tacacttggt gcagatgata aagctggaat agctgctata cttgaagctt
     6181 tagaacatgt tactacagaa aaaataccac atagagatat ttatctttgt tttacaatct
     6241 gtgaggaagc tggtatgcat ggtgtcaaaa actttaatcc tgacaacttg ccttgtaaag
     6301 atatggtgat tttagattct ggtggagcta ttggttcgat agcatacaaa gctcctgctc
     6361 aacaatctat aaaaatctct tttcatggaa agaaagcaca tgctggtata gaacctgaaa
     6421 aagggttaaa tgctatatta gtagcctctc atgcaataag caatatgcac ataggcagaa
     6481 tagatccatt gactacttca aatataggta aaatagaagg tggtggagct acaaacatag
     6541 taactgataa ggttacattg actgctgaaa ttaggtctca tatacctgaa actttagagt
     6601 atgagcttaa tcatatggaa aaatgttgta aggatgctgc atctaaattt aatactactt
     6661 atacctttga acatagtatg tcttacccta gttttgaact tagtagagat agtcacgttt
     6721 tcaagttaag tgaagaagca ataagacaag ttggtgttgt tccaaatcca atggtaattg
     6781 gtggtggaag tgacgcaaat atattagcta atcttggata taattgtgct atattaagtc
     6841 taggtatgta tgatgtacac acagttaatg aatatgtaaa tatagacgaa ttatatgata
     6901 ctgccaaaat agtttatcat atgattaaat tataaatatc ataatatacc tctttaaatt
     6961 ataaaaataa aaacctatgt atcttcaact ttataagtta tatattaaag ttgttttaca
     7021 taggttttag tatcttatat aataatttat tttaacattt ttcataataa gctttggtat
     7081 tttatatagt aatttgttct aacatttttc ataataagct tcaatatttt t
//
LOCUS       DAEQJM010000117         7112 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.120, whole genome shotgun sequence.
ACCESSION   DAEQJM010000117 DAEQJM010000000
VERSION     DAEQJM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7112
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.120"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            46..897
                     /locus_tag="KRQ43_003480"
     CDS             46..897
                     /locus_tag="KRQ43_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HBH2743814.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1030..2643)
                     /gene="ggt"
                     /locus_tag="KRQ43_003481"
     CDS             complement(1030..2643)
                     /gene="ggt"
                     /locus_tag="KRQ43_003481"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBH2743815.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2868..4805)
                     /locus_tag="KRQ43_003482"
     CDS             complement(2868..4805)
                     /locus_tag="KRQ43_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743816.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVKTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKMFFKDFEIEKINLYIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKFKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKIIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4792..5559)
                     /locus_tag="KRQ43_003483"
     CDS             complement(4792..5559)
                     /locus_tag="KRQ43_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743817.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALKGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTMDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5847..6521
                     /locus_tag="KRQ43_003484"
     CDS             5847..6521
                     /locus_tag="KRQ43_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743818.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6545..>7112
                     /locus_tag="KRQ43_003485"
     CDS             6545..>7112
                     /locus_tag="KRQ43_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH2743819.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLINEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVN"
BASE COUNT         2513 a         1036 c          839 g         2724 t
ORIGIN      
        1 atataaatta aaataaagat aatataaaca taggaggtac attctttgaa aaacattatt
       61 tcagcaaaag aacttatatc aaaactagaa aaaaatgata atctagttgt aatagattgc
      121 agatttgatc ttatcaatag aacttatggt attgattctt ataaaaaagg acatatcaaa
      181 ggcagtttta tcttagatat agacaaggat ttatcatctc ctacaaaaga acatggtggt
      241 aaaaatcctt tacaagaccc tttaatacta aaagaaaaat tagaaaaaat gggtgttgat
      301 aatgacacta cgattgtaac ttatgatgat ggagatttaa atggagcttg cagattattt
      361 ttccaattaa aacatttggg gcttaaaaat gtctatgtac tagatggggg aataacatct
      421 ttcgtaaagg aaggtggaga attggaagag aaagtgaata taccaagttg tacaggtaag
      481 gaaattagac caaatataaa caatgattta gttgttccaa tggaatatgt taagtctaaa
      541 ttatacaaaa aagatactgt aataatagat tgccgtgcta atgagagata ccagggttta
      601 gttgaacctg cttactcaaa agctggtcat ataccaagtg caaaaaatta tttttgtaag
      661 gatttaataa aaagtgactt tgaaaatggc tcacttaaag atatagaatt tttaaaaaaa
      721 ttctttaaag atttaaataa ttatgatgaa gtaattttat cttgtggttc agggatatct
      781 gcttgtgtta acagtcttgc tcttagagaa ctggatatac ctcacaagat ttatattggt
      841 agctttagtg actggattag ttatgatgac aatgaaatca aaactggtca agaataaggc
      901 tcataatcta tataaaatca gcatatgata gcttaaattt tgtaaaggcg tcagtcattg
      961 tagactttcg cctttactaa ttatttcata tactctttaa atttattata tatattttag
     1021 ttgataatat taataaactg caatatgacc atcacatctt gattccgtcc cacaaatata
     1081 actttcctgt tctgttttaa atattatttg acctcgtccc atgtcgacag tatcatgaat
     1141 tacttttatt tcatgaccct tttcaattaa tgaatctatt atatgctttg gcatctctgg
     1201 ttcaacttct atttcctttc cttttatcca ctgccatctt ggagcatcta gcgcctcttg
     1261 tggatttaat ccaaaatcaa tcatatttgt taacacttga atatgtcctt gtggttgcat
     1321 aaaagctccc attacaccaa atggacctat tgctttatct tctttaccta aaaatccagg
     1381 tattatagta tgataaggtt ttttaaatgg ttttactaca ttgtggtgtt tagggtctaa
     1441 attaaaatta tttcctctac tatgtaaagc aatcccagtt cttggtatca caattcctga
     1501 accaaaattt atgtaattgc tctgtatata tgaaaccata tttccatcct tatctgcagt
     1561 acaaaggtat actgtaccac cacaatatgg ctctcctgca gttggataca aagcctcttt
     1621 attgtcaatt aataaacttc tttttttggc atactcttgg cttagtaatt cctgaatctt
     1681 taccttcata tgctctatat cagttacata tgttttagaa tctgcaaaag ctaattttaa
     1741 actctctata attttatgta tgtcttctac attttctata tttccttcta attccaattc
     1801 ttttaatatg ttaagtgcca ttaaaactgt tattccatga ccatttggtg ggatttcaaa
     1861 tattttatat cccttatatt ctgtacttat aggttctacc catgttggat aaaaacactc
     1921 taagtcactc tttcttatag ccccattaaa ttttttagaa tattcatcta ttttatcagc
     1981 aagtcttcct ctataaaagc tttcagcctg agtatttgct atctcttcta atgtacttgc
     2041 ctgttcttca catataaata tatctccagc ctctggagct ttaccatctt tagaaaatgt
     2101 atcaaaccat ggtttgaact cttctccaat aagttctttt tcatagagtt catatgattt
     2161 tttccatacc ttagctacat taggagatac tacgtatccc tctcttgcat agtttatcgc
     2221 tggagataag cattccatta agctaagttt accatatttt ttatttaatt ctgaccaagc
     2281 tgcgggtatt ccaggtacag ttactgctcc aaacccatat tttggcattt ctttcatatt
     2341 attataattt tttaattcca tattttctgg agcaaagcca ctagaattta aaccatacaa
     2401 tcgtttttct tcctctatcc aaacaagggc atatgcatct cctccaatcc cattgcttgt
     2461 aggttctact actgctaatg tggcggctgt tgcaactgct gcatcaacag catttccacc
     2521 cttttttagt atttcaagtc cagcttgaga tgctaatggt gttgatgttg caactgctcc
     2581 atttttagca tacacgacat ttcttattga tgagtattta tgttggtagg cattaaactt
     2641 cataaatttc agctcctcgt cattttttat ttgatattct gcttagattt attatataac
     2701 atcaagtaat gtaactgata caaaatgata taaaatatag actttttcct aactttaatt
     2761 ttatctttaa ataaatatct taaactcaat tctagtattt tctatctgca cttaaataag
     2821 ttattttatt caaaacatat atctaattct tttgacttaa aaataattta ttcttttatc
     2881 atgtttagag catattttaa agttaaaaaa taatatataa aatatcctat aaaataaatg
     2941 actagagtta tgataattgg tacaagtaat gaccttggta taaacttttg tgctatagac
     3001 atagcaaata aattatgaac tgtacctaca actaatggca ttaaaaatat aatttttaac
     3061 tgttttgata ttattttctc aatatcttta ttatttgctc caagttttat taacataata
     3121 tatctttcct tatcatcata tatatttgat aattgtttaa ataagattat actacctgta
     3181 cataaaagaa atactacaga caaaaatatg cctataaaca gcattagacc acttaatttt
     3241 atcaagttat tataactttc aatacttgat gtaaaattaa aaggataagt aaatttcata
     3301 ttttcactta ctatattttt aaattttaaa gtcaaatcca gttctttttt ttcatttttt
     3361 atatcaatta atcttattaa tctagaattt ccatgtaatt ttaactgatt aaatacgtca
     3421 tcttttacta caattaaatc aaacgtagct tgtgaattta tttctggctc caagatgctt
     3481 ttttgtacct taaacagatt tatatcatac tcatttgtat ctttaatata caagtttatt
     3541 ttttcaatct caaagtcttt aaaaaacatt tttttgtatg aatcagaaac atagtacaca
     3601 gattcctttg aagttaattc ttcataattg ttattctgat attgtcttaa ttttttaaaa
     3661 tcactttctc taataatatc tacagaagtt ctatcttcta tataactatt tccattttta
     3721 taatacattt caatatttat atctttgtct ataagttcta ttgttttatc aaagattatc
     3781 ttattatctt ttttatattt atataataat ttgtcaattt cgttatttac ataagaattt
     3841 cctaaattta tggtataact gtatttataa ttttcactta tgttcctatc tatatcgtaa
     3901 taaagtgata tggtaaaccc tagcatagtt acactcgtag ctattaatat tgctattaca
     3961 gccaatacac tactattgct ctttaattta aatccaagtt cagaaaatgc aattaaattc
     4021 tgtcccttat aataaaaact ttttctcttc ttaacagcat caataatcat atacatagtt
     4081 gatgaaaaaa ataaaaaagt tccaggtatt attgtaacta atataaaaac tgaaagcata
     4141 atattttcag caataaaata actaattgac attaaataag aaatagctat taataaaaca
     4201 ccaagtacac attttaactt tataaatttt ttaaacttat acttttctgg atatttatta
     4261 aataactcta taattctctt atttctgata actatagtat ttcttattcc aataactata
     4321 aatattatta aaaataccgc tagtgtctta actaaggcct ttatacttaa gttcatattt
     4381 actactatca tttcattcat taattttaca agcatcatag tcataagctt tgaaaataac
     4441 agtcctaaaa atatacctat tagtattgca actataccca tcaaaaaagt ttcatataaa
     4501 aatatttttc ctatctgatt tttcctcatt ccaagtaaac tataagttcc tacttctcgc
     4561 ctacgtctat tgaaaaaaaa tgagtttgaa taatatataa ataaaaatac aaataccact
     4621 attacaattg aacttgtatt aatactcatc ctagtttttt ctccaagtga actcaacgct
     4681 tcattatact ctatagattt aaaactaaaa aatacaaata cactaaatac aattgaaata
     4741 aagtacatta aataattaaa aaaactattc tttacatttt gcattgcaat tctaaataaa
     4801 gtcattttta ttaactcctc caattaagga aactgtattt actattttat tatagaactc
     4861 tctgttactt tctcccttta caatttctgt gaatattatt ccatccttta taaagagtat
     4921 tctattgcaa aaactcgcac ttatagcatc atgagttacc atcaatattg ttttattgct
     4981 gtctttgttt aattttaata gacaattcaa caaatcccta gcagatttag aatctaatgc
     5041 tcctgtaggc tcatctgcaa gtactaatga tggttttgtt gctatagctc tacatacagc
     5101 tcctctttgc ttttgtccac cagaaacttc gccaggatat ttatctaata tagattctat
     5161 atttaattct tttgaaatct cttttattct attttctatt actgatactc tttcattttt
     5221 taaagaaaga ggcaacatta tattttcttt tattgtaagt gtatccaaaa gattagaatc
     5281 ttgaaataca aagcctagat tatcacgtct aaaatctgcc aattcatttt gcttcatttt
     5341 aatagtattc tttccattta tataaatatc tcctgatgaa ggtaaatcca ttgtagaaat
     5401 aatatttaaa agtgttgatt taccagcacc ggaagacccc ataataccaa caaattctcc
     5461 tttataaacc ttgaaagtta ttccttttag agcttcatgt tttgaacctt ttcttccata
     5521 ctcctttttt atattttcaa cagataatat ttcttccata gttaataatc acctttcatc
     5581 acaattagtt atttatcaat tctcacaaat atattatata tattaaaatg gcttttaaac
     5641 atttaattat attaatttaa ggttacattt tcgtaagtat taattatatt tcttcaaatt
     5701 tattgcaatt atgtttaaaa tataatttat caagtaaaat atagttatat taatataatt
     5761 attttaggta ataaggtaga aatattttaa tttatcaagt agaatatagt tatgttaata
     5821 taactatttt gaattaggag gtaagaatgt ttaaaataat ggtagttgaa gatgacgtct
     5881 cattgaaaaa tatcatagca aagtgtctta ctaaatgggg acatgatgtt catcaaatag
     5941 aaaatcttga aaatataata gaagagttca aaaactataa cccagaatta gttttattgg
     6001 acataaacct tccattttat gatggttttc attggtgtaa tgaaataaga aaaatttcaa
     6061 aagttcctat aatttttatt tcttcaagaa attctaatat ggatgtaata atgggtgtaa
     6121 atttaggtgc agatgattat atacaaaaac ctttttctgt agatgtctta gtagctaaag
     6181 ttaatgccct tttaagaaga acttataatt ttgttgataa taactcaaat cagattattc
     6241 acaatggtgt tactttagat ttatcaactg caacaataaa ctatgaagat aatactattg
     6301 agctaacaaa aaatgaaatc aaaattcttc atgagcttat gaaatataag gggcagatag
     6361 taagtaggaa taaactcatg aaaaaattat gggataatga ttggtttgta gatgataata
     6421 cattaactgt caatgtaaat agaatacgct caaaattaaa tgaaattggt ttagaagatt
     6481 ttatagaaac aaaaagagga ttgggttata taatcagtta aaacaattct aagtaggtga
     6541 atttatgagc tttaaagatt ttctcaagga taaactaggt tttttagtat acaattttac
     6601 tttcttaatt tttacagtat cagttattat attttctcct gtagatgttt ttctgactga
     6661 tactatttta tatatattag ttgtaaatgt tgtgttttta tttttatatc tatttattag
     6721 ctacatcaag aagaacaaat ttttagataa gataaaaaat gatacattca aaattaatat
     6781 gaatgatata gaattagcta gatgtaaaaa tgaagaaaaa atatacttga acattattaa
     6841 aaatcatcaa tatcaatgta ataacataat aaataataat atcgagaaat ttgaagaaaa
     6901 caaagagatt ttaaatatgt gggtacacga tgtaaagata cctatagcta taataaaact
     6961 cattcttgaa caaaatgaaa atttaattaa tgaaaaaatt tcagatgaca tagatagtga
     7021 aatatttaga attgaaaact ccgttgaaaa aattttatat ttatcaagac tcgaagattt
     7081 tcataaggat tttttaattc aagaggtaaa ta
//
LOCUS       DAEQJM010000118         7018 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.121, whole genome shotgun sequence.
ACCESSION   DAEQJM010000118 DAEQJM010000000
VERSION     DAEQJM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7018
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.121"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            328..474
                     /locus_tag="KRQ43_003486"
     CDS             328..474
                     /locus_tag="KRQ43_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HBH2743820.1"
                     /translation="MRKIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFF"
     gene            475..1068
                     /locus_tag="KRQ43_003487"
     CDS             475..1068
                     /locus_tag="KRQ43_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HBH2743821.1"
                     /translation="MRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYY
                     NLRTITWNDRVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNY
                     PYQIFEFTSSRDCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSIGPMG
                     ATGPTGATGNSSQPIANFLVNAPSPQTLNNGNAITGW"
     gene            1237..1428
                     /locus_tag="KRQ43_003488"
     CDS             1237..1428
                     /locus_tag="KRQ43_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HBH2743822.1"
                     /translation="MAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQ
                     SAGTAATLTIFRIADTVMT"
     gene            complement(1663..3261)
                     /locus_tag="KRQ43_003489"
     CDS             complement(1663..3261)
                     /locus_tag="KRQ43_003489"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HBH2743823.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFDVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            4139..6781
                     /gene="adhE"
                     /locus_tag="KRQ43_003490"
                     /gene_synonym="adhC"
     CDS             4139..6781
                     /gene="adhE"
                     /locus_tag="KRQ43_003490"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH2743824.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPDRVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGNTDQEKVDNLIKAIDELKARVGLPKTIKEAGVEESKFLETLDVMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT         2657 a          905 c         1124 g         2332 t
ORIGIN      
        1 tggtaatata ttctatttac aattttataa ctttggttta caataataga gacaataaat
       61 cctaaaaaac ataataagaa aaaagtgctt aatattttag aaagactggt ttagtttaca
      121 ccagctaagc cagtcaagga ataatttaaa gtgtaatata taataatgaa aaagaacatg
      181 ctattagaag tttctaatga catgttcttt ttttgtagaa atcagcatta ttatataaaa
      241 atttaatact ataaatttta attgtattgt aactaagcat gtattttaaa catagtatga
      301 tatagaccca aaatggaggg attataaatg agaaaaatta tactttattt aaatgatgat
      361 acttttatat ctaaaaaata tccagataaa aactttagta atttagatta ttgcttaata
      421 ggaagtaaat gttcaaatag ttttgtaaaa gaaaagttga ttactttttt ttaagtgaga
      481 ataccagata tattaaaaga caaaagtata ttaaaagcag agttatttat tcatattgat
      541 tcaaataaga atcatatttt taaagaaaaa gtagatattg aaattaaaag aataagtgaa
      601 tattataatt tacgaactat aacatggaat gatagagtgt ctatggaaaa tatcagggga
      661 tatttaccaa ttgggataag tgatacatcc aactatattt gtttaaatat tacgggaact
      721 ataaaagcat gggcaatgaa taaatatcct aattatgggt tagctttatc tttaaattac
      781 ccttatcaga tttttgaatt tacatctagt agggattgta acaaaccgta tatacttgta
      841 acatttgaag atagaattat agataattgt tatcctaaat gtgagtgtct tccaattaga
      901 attacaggtc caatgggacc aagaggagcg acaggaagta taggaccaat gggagcaaca
      961 ggtccaacag gagcaacagg caattcctct cagccaattg ctaacttcct cgtaaatgca
     1021 ccatctccac aaacactaaa taatggaaat gctataacag gttggtaaac aataatagga
     1081 aatagttcaa gtataacagt agatgcaaat ggtacgttta cagtacaaga aaatggtgtg
     1141 tattatatat cagtttcagt agcattacaa ccaggttcat caagtataaa tcaatattct
     1201 tttgctatcc tattcccaat tttaggagga aaagatttgg cagggcttac tactgagcca
     1261 ggaggcggag gagtactttc tggatatttt gctggttttt tatttggggg gactactttt
     1321 acaataaata atttttcatc tacaacagta gggatacgaa atgggcaatc agcaggaact
     1381 gcggctactt tgacgatatt tagaatagct gatactgtta tgacttaaaa cgtgtctaaa
     1441 ataatcttaa aaactattta ggttttattt aaatgacaaa agtattttta tatattgagt
     1501 tttacctatt ttagaatgaa taaaataaca ataataataa aatatattca taaaaatttt
     1561 aaatttatgg atttttattt aactttatta tcaatatatg tataataaaa aactgtctca
     1621 aatatagatt tgagacagtt ttcgttattt aaaaatttta tattatttaa aatttttgat
     1681 tgcagtagtt aaattaggga ctaattgttt ttttcttgat acaacacctg gtgcaaatgt
     1741 accttgaaca ccttcaacat caaatgcgtt agcaattaag ctatcttctg ctttatagat
     1801 taaataagaa ccttctttga ttatatctgt aaccgcaaga attagtttgt cataatcagt
     1861 cgaatttata taagataaaa actcatcttt tttagcaaat atagagtcta tgtctaaggt
     1921 aaatacttgt ccaataccaa ctctatgtcc actcatatta aattctttaa aatccatatt
     1981 tactatttct tctatagtat attcatctaa agaagtaccg catttaaaca tatccatagc
     2041 gtatttttcc atgtctactt ttgctatttt acttaattct tcacaagctt tcttatccat
     2101 atcagttgtt gttggagact taaataataa tgtatctgat aatatagcag ataaaagaag
     2161 cccagctatt tcataaggta tctcaacatt gttttctttg tacatttgat aaattatagt
     2221 actattgcat ccaacaggca taactctaaa tgacatagga acatcagtag aaataccacc
     2281 aagtttatga tggtcaatta tttcaactat gtttgcttgt tcaattccat cagcactttg
     2341 agcatattcg ttatggtcaa ctaaaacaac attcttttta gatgggttta atagatgacc
     2401 ttttgaaact aaacctaaaa acttattatc atcatctaat attggataag atctgaagtt
     2461 tgtttctagc ataatctctt ttatttcatc catataatca tcttctttga atgtaattaa
     2521 attttctgta gcttctatag agtctaagaa actacattga tttattacat tagaagtttt
     2581 ataattgtca ctttcaacag aaacaacaga cactccattt atcttagcaa gagctagcaa
     2641 atcttttgaa atctctgtat gattagtaag tattaaaagt ttaacttttg tatcaatagc
     2701 atattcaata ctatcatatc tatctccaac aatagctatg tctccttctt ttaaagtctc
     2761 tattagagtc tccattccaa atgataaagt gactactcta ccttttatat cttcaccaca
     2821 gtccacaaga atagtaccat taaggttttt acaaatgttt gatagtgatg tgtgtatagt
     2881 tgtaaagtgt tgatgaagta gatttttagc tatttctttc atagtaatga taccagcaaa
     2941 agttccatca tcataagtta caggtagtgt tttaacattt ttttcatcca taaggttata
     3001 agcctctaat atagatgaag ttggtgttaa aggtactact ttatcataat ttaaatctct
     3061 aacttgtatt ctaacattat ctaaaatttc aggtgcatct accttaaagt aatccaaggc
     3121 atatttagct tcttttctga tatctcctaa agcataagct gttgctttta ttcctagttt
     3181 gttctttaaa tgtgctaatg aaattgcaga acatattgaa tctgtatctg gatttttatg
     3241 tccgaaaact aataaactca ttttaatact cctttcaaaa cttgaatata ataataattg
     3301 ataaaaatat tatatcaaaa ggtagtgagt atttgttgta aaaagaaaaa aatttagtga
     3361 aaaaatatta tataaaattt atttcttaca taaatactac aaatttaata taaaaattat
     3421 tattatatat atttttaccc aaccaaacat agaatcaaat ttacttttat ttaaaataaa
     3481 ttgattaaat ctacctggga aaaaattaat taatatgtta ataaattaaa aatttataaa
     3541 tattttatac tgtaaaaaat tttgtatata tattatcatt aaaaaattaa cggtcttaat
     3601 ataaaaatta tttatctata tgaaaagcat aattattaca tattgactta aaaataactt
     3661 atagagatta gaataatttt agtttgtata ttttttaaaa ccatacagtt gttataaaaa
     3721 gaaaaattgc acacaagtca aaaataagtg ttattttata aaaatacgac aaaaatttta
     3781 tttactactt atacaaataa catgcaaata acatataaaa tttaataagt aaaaaaaatg
     3841 aaagatataa attatcattt tagtatttta tttagttgaa gtaaattatt caaatgaaat
     3901 atatctcatt tagataaaaa attttagtaa aagtaaaaaa aataatatat ttgttaaaaa
     3961 ataaattgac aaaatattca gaaaaaaact tcttgaccta agagagtaaa ataaataaaa
     4021 tctaaggtat agagatgaaa tctataaaat tattttaagt ataagttaaa aatatagatg
     4081 gtgcatttaa gatttataaa aattagagat gcataattat tttagggagg tttttagtat
     4141 ggagaaaaaa gaaaaggtag tagaaaaatc aaatgttgaa gtatgtagtc ctgaaattgt
     4201 caacagtgtt gaaacattaa gaatgagatt agaagaaatt agattggcac aaaaagaatt
     4261 tgcaacattt acgcaagaac aggtagataa gattttctta gctgcttcaa ctgcagctaa
     4321 tcaacaaaga atacctctag caaaaatggc agtggaagag actggtatgg gtattgttga
     4381 agataaggtt ataaaaaacc attttgcctc agaatatatc tataatgctt ataaagatac
     4441 taaaacttgt ggtgtcatag aaaaagatga agcatttggt tttacaagaa ttgctgagcc
     4501 agtaggtgtt ttatcagcag ttataccaac aactaatcct acatcaactg caatattcaa
     4561 atccctaata gcactaaaaa ctagaaatgg tataattttc tctcctcatc caagagctaa
     4621 aaactgtact atagaagcag ctagagttgt acatgatgcg gcagttaagg caggagcacc
     4681 aaaaggactt ataggttggg tagatgttcc ttcgattgaa ttaactaatg ttgtcatggc
     4741 agaggcagac cttatattag ctactggtgg acctggaatg gttaaatctg catactcttc
     4801 aggtaaacca gctgttggag ttgggcctgg aaatgtacct gcaataatag atgagagtgc
     4861 agatataaaa atggctgtaa gttcaatctt agtatcaaaa tcattcgata atggtatgat
     4921 atgtgcttcc gagcaagctg taatagtacc agaaaaaata tatgaagaag ttaaaaaaga
     4981 atttaaatac cgtggagcac atttcctaaa taaagaagaa actgaaaaag taggaaaagt
     5041 agtaataatt gatggttcat taaatgccag aatagttgga caaccagcac atgtaatagc
     5101 caaaatggcg gatgtagaag ttccaaaaac agctagaata ataattggtg aagtagaatc
     5161 tgttgaatta aatgaacctt ttgcacatga aaaactttct cctgtacttg caatgtacaa
     5221 atctaaaagt tttgaagatg cagttgctaa agctgaaaaa ttagttgcag atggtggata
     5281 tggccataca tcttcgttat atgcagactc tataaatcat ccagatagag tagagaagtt
     5341 tgtaaatgct atgaaaactt gtagagtatt agttaatact ccatcgtcac aaggtggtat
     5401 aggtgactta tataacttta aattagcacc atctcttact cttggttgtg gttcttgggg
     5461 tggaaactca gtatctgaaa acgtgggagt gaaacattta cttaatatca agacagtagc
     5521 tgaaaggaga gagaatatgc tttggtttag agcaccagaa aaggtttatt tcaaaaaagg
     5581 ttgtttaggt gtagcagcaa gagaatttaa agatgttatg gataaaaaga aagcctttat
     5641 agtaacagat tctttccttt acaataatgg atacactaag aagctaactg atttgttgga
     5701 tgagatggga attaagcata ctacattctt tgatgttgct ccagacccaa cattagcttg
     5761 tgcaagagaa ggagctaagg ctatggctga tttccaacca gatttaataa tagctgtagg
     5821 tggaggtagc gcaatggatg ctggtaagat aatgtgggta atgtatgagc atccagaggt
     5881 agacttccaa gatttggcta tgagatttat ggatataaga aaaagagtat atgtatttcc
     5941 taagatgggt gaaaaagcgt attttgctgc tatcccaact tcagcaggaa ctggttcaga
     6001 agtaactcca tttgcagtta taactgacca agattcaggt gtaaagtacc cattagcaga
     6061 ttatgaatta atgccaaaca tggctataat tgatgctgat atgatgatgg agatgccacc
     6121 aagattaaca gcagcatcag gtgttgatgc tttaacacat gcattagaag catatgtatc
     6181 tatgttaaga actgaaccag ctgacggtct agcactacaa gcaggtaaaa taatatttga
     6241 atatctacct cgtgcataca aaaatggaaa gaatgataaa gaagcaagag aaaaaatggc
     6301 aatggcatct actatggcag gaatgtcttt tgcaaatgcc ttcttaggaa tatgtcactc
     6361 tttagcacat aaattaggtg cattccacca tgttcaacac ggtgttgcaa atgcattatt
     6421 aataaatgaa gtaattaagt tcaattgtgc agaagctcca aataagatgg gtgcattctc
     6481 acaatacaga tatcctgatt gtatacaaag atatgctgaa tttgcttctt ttgcaggaat
     6541 caagggaaat acagaccaag aaaaagtaga taaccttata aaagcaatag atgaattaaa
     6601 ggcaagagta ggacttccta aaactataaa agaggctgga gtagaagaat ctaaattctt
     6661 agaaacattg gatgttatgg ttgaacaagc ttttgatgac caatgtacag gtgctaatcc
     6721 tagataccca ttgatgagtg aattaaaaga gatatatcta aaagtttatt atggtaaata
     6781 atattcattg tacaacatag gttctattgg gtttgtatat aaattattag atttgaatat
     6841 aaatagagtt ttattagaga aacgtagaag taactataaa taatagatta taacttaaat
     6901 tctgaatgga aatgataaaa agtcagtaat ttaatggtaa tttcgaatat gtgtatttaa
     6961 tcaattaact ttaaaattag tcggaaaatt tttttattac atataatttt aaagcata
//
LOCUS       DAEQJM010000119         6768 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.122, whole genome shotgun sequence.
ACCESSION   DAEQJM010000119 DAEQJM010000000
VERSION     DAEQJM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6768
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.122"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..394
                     /locus_tag="KRQ43_003491"
     CDS             <1..394
                     /locus_tag="KRQ43_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH2743825.1"
                     /translation="FISKKIILDLNNLNFKVLSDEKWLYFIFEQLLSNSLKYSSLGDN
                     ISIYCKRTKNYLQLRVEDTGCGIKKEDLNRIFNKGFTGNNGRNNSKSTGLGLYLVKEL
                     CDKLGHKIDVDSEYNQYTKFTITFKCDL"
     gene            506..1735
                     /locus_tag="KRQ43_003492"
     CDS             506..1735
                     /locus_tag="KRQ43_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH2743826.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            1743..2417
                     /locus_tag="KRQ43_003493"
     CDS             1743..2417
                     /locus_tag="KRQ43_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743827.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLVN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            2420..3652
                     /locus_tag="KRQ43_003494"
     CDS             2420..3652
                     /locus_tag="KRQ43_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743828.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(3938..5203)
                     /locus_tag="KRQ43_003495"
     CDS             complement(3938..5203)
                     /locus_tag="KRQ43_003495"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBH2743829.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(5256..6404)
                     /locus_tag="KRQ43_003496"
     CDS             complement(5256..6404)
                     /locus_tag="KRQ43_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH2743830.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQNSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSKKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(6495..>6768)
                     /locus_tag="KRQ43_003497"
     CDS             complement(6495..>6768)
                     /locus_tag="KRQ43_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH2743831.1"
                     /translation="EAYKRIAFEEAEHAAKFAELLGEVVVADTKENLRVRVDAEYGAT
                     DGKLKLAKRAKELGLDAIHDTVHEMCKDEARHGKAFLGLLNRHFGK"
BASE COUNT         2343 a         1085 c          936 g         2404 t
ORIGIN      
        1 ttttatttca aaaaaaatta ttttagactt aaataatttg aattttaagg ttttatctga
       61 tgaaaaatgg ctatacttca tattcgagca attattgagt aattccctaa aatactcctc
      121 attaggagat aatatatcta tctattgcaa aagaaccaaa aattatttac aattaagagt
      181 ggaagatact ggttgtggta taaaaaagga agatttaaat cgaatattca ataagggatt
      241 tacaggtaat aatggaagaa acaattctaa atctacaggt cttgggcttt atttagtaaa
      301 agaactttgt gataagcttg gtcataaaat tgatgtagat tcagagtaca accaatatac
      361 aaaatttact attacattca aatgtgattt atagtatctt attattgata gtttattttc
      421 attaacttat attcaacttc ttatagtaat tctatatgta catcccagta tataattaag
      481 tagtttttat aaaaaggagg aagacatgtc ttttctaaaa aaatttaaaa ataaaagatt
      541 tagaaataac agttttaaaa gtaacaactt tagaaatagc agttttggaa gtagtggctt
      601 caagtctaaa aataaaggtt ttaaaaacaa tccctttaaa aataagagat tcaaaatata
      661 tgcaggaata gcagtaatca tacttttaat tctaggagtt cttgcttatg ttgattcgaa
      721 aaacactgaa ttacaagcta atgaaaattt tatcgaaaca tatactattc ctgaaaatga
      781 aaaaatattt ataaatggga tggttgttcc taagcaaact aaggacttca atatatctgg
      841 agattatgag ttaagtgatg ttaatgttac aaatggtcaa aaagtaaatc aaggagacct
      901 tctttttact gctaaaaatc caactataat agcagaaata gatagtttaa aatcacaact
      961 tagtcaatac aaaaaacaaa aaatatcact ttctgatatt gctgaaaata aagatgctat
     1021 tgcttctata aatgcacaga taactgcttt aaactctcag atagcttctc tggataaaaa
     1081 agcttatgac agagttactg ctccttttga tggcacagta tacttgaatg accaaactgg
     1141 aaatccagac caaccagttt catttatgac tattcaaggt ctagagtttt atatgaaagg
     1201 acaagcaagt gaacaagatt tacctaaaat gaagattgac caaatggtca atatactagt
     1261 tttttcaact gaccaaaagc ttactggtag aataagtttt atatctgata aaccatctac
     1321 tccaaatact gaaatgggag ctcagcagaa tacactatct tattatgata taaacatagc
     1381 atttgataat caagaaggat tagtaaatgg attccatctt caagcatcac ttgaagtagc
     1441 taattcaagc tttaaaatac cagcatcttg tgtacttaaa gacaacaaac actcatatgt
     1501 atttaaggat ttagatggta tattgaaaaa gcaaattgta gatgtagcaa gtcaaaatga
     1561 tgattttgct gtagttagag gcggtcttga acaaggcgat ataataataa aacaccctac
     1621 taaagaaatg aaagaaggag acccagttca aggcgatggc gtaactgctg gttctaataa
     1681 tggagatact actccaaaca aaaaagtaga agaagttact atggatgtga attaatttac
     1741 atatgttaat taaattagaa aatattcaaa aatattacaa agtagggaaa gatgaattac
     1801 atgttttaaa atccttaaat ttagaaattg aatctggaga atttgtcatg ataatgggta
     1861 agtctggtag tggtaaaact actttactta atatcttagg ttttctagat gtatttgatg
     1921 aaggaagata tatatttgat ggaacagatg taactaattt gagtgaaaat gaacgttctg
     1981 tttttagaaa tattaatatt ggatttgttt tccaacaatt taatttaata gaaactctaa
     2041 atgtatatca aaatgtagag ttgcctctaa tttacaataa agcactaaaa aaatctaata
     2101 gagaagaaat tgttaaagat aaattaagtt ctgttgggct tttggacaag cttaagcaga
     2161 aaccacttca attatctggt ggtcaacaac agcgtgtagc cattgcacgt tgcctagtaa
     2221 atgaccctca gataatcttt gctgatgaac cgactggggc attagatagt gaaactagca
     2281 gagaaattat ggagctttta acaaggctca acaaacaagg taagactata ataatggtta
     2341 cacatgatca agatttaact aagtatgcaa ctaaggttat acgacttaaa gatggtgtgt
     2401 ttacttcgga ggtgtaatca tgagtttatt aaaaaattct ttggccaatt taaaaggtca
     2461 caagcttcgt gtatttgtag ctttactctg gattataata ggaataactt cagtaatact
     2521 tgttagttct ataggtaatg gatttcaaaa agaaattaag aaatctgtaa acaatgtaaa
     2581 ccctaataaa actactattt cgtttgaatc agccgataac acaggtctta ctgatgatat
     2641 gagtattttt ttaaaaccct ttaatgcaaa agatttagaa gaattatcat ttgttgaagg
     2701 agtagaaaga atagctcctt caagagatgg gtttaacctt gattcagttt actcttcaca
     2761 agcatctttt gataaaaaaa ctacgtatgt tgatgttgga ccagtaaaaa aagattctaa
     2821 aataaattta atttgtggta gagatttttc tttagatgat gaaaaaagaa aagtaatttt
     2881 acttacatta caaagtacaa gtgaaatttt tgaaaatcca gaagatgcct taggtcatgg
     2941 tatcaacata aatggaacta tatttgaaat aataggggta ttagatgatt ctcagcaaaa
     3001 ccaagctgga ggattctttg gaggttacca agatatgcaa tttactactt ccctagtacc
     3061 taaaaaggct tttgacactt taatgagtca aaattcttat tcaaatgaaa tttaccagtt
     3121 agacttagtt tcttctaaag gctataatgt aaatgaagtt gcaaacaatg ttatagctaa
     3181 attatatgag atgcaccctg gtatcaatgg ttcttatact acaccagacc caactgaaca
     3241 gacagcttat cttgaaagca ttaattccaa tgtaaacaaa tatgtatcta taataactgt
     3301 agttgcaatg tttgttggtg gtattggtgt aatgaatata atgtatgtat ctgttatgga
     3361 aagacaaaga gaaattggta taagacgtgc tattggagca aaacctaggt ctatattatt
     3421 tcaattttta gttgaagctg tttttataac agtatgtggt ggaattttag gaactatagt
     3481 tggatttgct gctactaact atgtttctaa atatataggt tttgaagcta tacctagctt
     3541 aaatagctta ttttatgcaa ttgtagctac tatattgact ggagttgtat ttggtctgat
     3601 tccagccttt aaagcttcta aactagaccc tataaaggca atttataagt agaaattgta
     3661 taaagatttt cgatttttag attagtttat ataaaacata cttaaatata taacgcacta
     3721 ttatatatga tagattagga acttaatctt tccaaatata atagtgcgtt ctttcataaa
     3781 aaggattctc ttccttacta tatctaaatt accaagatgt tatgttctaa ttgttcaaac
     3841 taatacttcc aattttgatt aatcaatctc attctgctga tatacaatct tttactttca
     3901 atcattgtac actccgcctt aaaaaaataa tcttaaatta ggcgttatat acaatctccc
     3961 cattacatat tgtataatta acctttccat ataaagattt acctttaaac ggtgaattat
     4021 cagctttaga aacaaagctt tcaactgtcc attcttcttc tggattgaat ataacaatgt
     4081 ctgctacagc cccttcttct ataaatccaa tatttaaatt gtacaacttt gcaggattta
     4141 tagacatttt ttctattaac tgcatcatac taagatgatt tttatgcacc aaatttgtta
     4201 ttccaagagc taaagaagtt tcaagcccaa taattccact tggagctttt ataaactctc
     4261 tatctttttc ttctttacta tgaggtgcat ggtccgttgc tattatttca atagtaccat
     4321 catttaatcc ctctataatc ttatctctgt cccatttact tcttagaggt ggattcattt
     4381 ttgcatttgt tccaaactcc aatacatctt cctcagtcaa tgtaaagtga tgtggtgaag
     4441 cttctgcaac tacatttgca cctaagtatt ttgcaaacct aaccatatca acagatacac
     4501 ctgaacttat atgttgtata tcaactttag caccagtctt tagtgccaac atacaatctc
     4561 tggctaccat aacatcttct gctacacttg atgcaccttt taatcctagt tctgaagcta
     4621 cctttcctgc atttacacct ggatttccaa ctaaagaagg gtcttcttca tgaaaactaa
     4681 gtggtacatc caactctttt gccttaatca ttgcctccat aattagattg ctatccatta
     4741 aaggtaatcc atcatcagta aaccctggta caccagcttt tttaagagct tccatatcaa
     4801 ctaactcttt accttcaaaa cctttagtta tagctgctgc ttgtaaaaca tttatacatg
     4861 cattttttga cttttcttta acataattaa aagtatcttc attatctaca ataggattag
     4921 tatttgccat acatataaca gttgtaaatc cacctctagc agcagattta gctccacttt
     4981 ctatatcttc tttatatgta aacccagggt ctctaaagtg tacatgtaca tccactaaac
     5041 ctggagcaac tacattacca ctagcatcta ttattttttc atattcatca ctttcatcaa
     5101 acttgcctat tttataaatt ttattttctt ttataattaa gtcaatattc tcatctcttt
     5161 gacttttagg gtctattact ctaccatttt taattaaaat catattattt ctcctttata
     5221 tttttaattt atatagactc atataatatt atacattatt ttacatactt aaatacaaaa
     5281 ttacgtttga catcaatagc ctttttagga caaagttcat ggcaacagta acatcttata
     5341 catttactta agtctataat agcaccttta gtccctatct ctatagtgga tgcaggacaa
     5401 gcttccttgc attttccaca ttttatgcaa tcttgaaatc ttaccacagg ctttggtgtt
     5461 ataagctttg aaataggttc atttaaaaat tttggtagct ttacggaaaa caatcttaaa
     5521 tccttactta catttggaat cttgtaattt tttataatta aatcttttat atcttcacct
     5581 aaaatttcaa tatctgaaaa atcttcttgt atatagcctc tcttaatagc acctctaatt
     5641 gtagcaactc tatttggaag taaacttata atcttacatg caacaacatc tatagcatat
     5701 ggattttgtg atgctaataa aactcctatt tctcgagtag taccagctga aggtccatca
     5761 ccttccatac ctactatacc atccataatt gtcaatgttg gttttatata atcacaaata
     5821 tctaaaagta cattttcgca aaacaactct tctgtaggaa atctataatg tatctctgct
     5881 tttttcaatc ctgctatgca tccatataag ttttttgtac caccagtaaa ggttgccatt
     5941 atatgagtct ttaatttaca aagatttatt atataatctg aatctactat tggtttaata
     6001 atatccatat attttagaac atgtgctttt ttactatgta tcttaacatc tgaaacatca
     6061 taatttaact taatgcccag ttcatttgct acttcttcaa ttccagatgc cttataaatg
     6121 ctcttaagag aattttgatt atatggacca ccagggctat ctgctattgt aatatcacaa
     6181 tttaactcta aaagtttttc acatacaact tttacaacca taggatgtgt agttgtagct
     6241 tcttcaggct tttttttcat taataaattt ggttttataa gtactttgct tcctttttta
     6301 acaaacttat ctataccacc aatatcctct aaattttttt caatagataa ctttacttct
     6361 tcataattgt aagttttaca actcctaaca gataccgact tcatattatc tccatccttc
     6421 tatcacaaca gtttatttgt ataatttaaa aaaggagaaa ccaaagtttc tccttttaat
     6481 ctatgtttta attattattt tccaaaatgt ctgtttaata atcctaagaa tgctttacca
     6541 tgtctagctt cgtctttaca catttcatgt actgtatcat gtatagcatc taatcctaat
     6601 tctttagctc tcttagctaa ttttaatttt ccatcagttg caccatactc agcatcaact
     6661 ctaactctta agttttcttt tgtatctgca actacaactt ctccaagaag ttctgcaaat
     6721 ttagcagcat gttcagcctc ttcaaaagct attctcttat atgcttca
//
LOCUS       DAEQJM010000120         6762 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.123, whole genome shotgun sequence.
ACCESSION   DAEQJM010000120 DAEQJM010000000
VERSION     DAEQJM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6762
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.123"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(177..785)
                     /locus_tag="KRQ43_003498"
     CDS             complement(177..785)
                     /locus_tag="KRQ43_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBH2743832.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(894..3632)
                     /locus_tag="KRQ43_003499"
     CDS             complement(894..3632)
                     /locus_tag="KRQ43_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBH2743833.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNRKFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3780..4571)
                     /locus_tag="KRQ43_003500"
     CDS             complement(3780..4571)
                     /locus_tag="KRQ43_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH2743834.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4607..5263)
                     /locus_tag="KRQ43_003501"
     CDS             complement(4607..5263)
                     /locus_tag="KRQ43_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743835.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5256..6221)
                     /locus_tag="KRQ43_003502"
     CDS             complement(5256..6221)
                     /locus_tag="KRQ43_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HBH2743836.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEHVKQYLTSKGIRWEEMINE"
     regulatory      complement(6327..6433)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
BASE COUNT         2168 a         1128 c          609 g         2857 t
ORIGIN      
        1 atagctcatt tcgccaaaat atatctttct ttatatcatt aaaataatta taaatttatt
       61 aaatatgttt gtaattctat aaagttattt ttatcaaact aaaaattcta taaaaaaata
      121 agatacatac ctataaaata ccttcctata gatacatatc ttacctatat aaaaacttat
      181 tctatataaa aacgccataa aaaatctttt gcttcttctg cataatctat atttatacgt
      241 ttactagttt ttatatctaa ctcatcttta ctaaatactt tttttccttt atcatcataa
      301 taaaaatcac ttatatataa ttcttcaccc attatactct tactatttag acttctatct
      361 atttttaaag ctttgcaaag ttttcctggt ccgttagtaa tattttttac ttgatattta
      421 ctcaactcag tgtaagcttt gttgtatcta ttcatagata tctcatctaa agaagttata
      481 ggctctaccc ctcttattaa tacacactct ggcacatttt ctatatttgc agataaattt
      541 aagcaattat acataccata aattaaataa acatatatat gtccaccatc taaatataat
      601 ggcttagttc tatctgtctt tttattgcca tatacatgtg ctcctttatc atttacaccc
      661 atgtatgctt ctgtctctat gattttggta acaattactt tattttcata tttccttatt
      721 agatatttac ctaatattga tttggctaaa tcaattccat tttttctaaa aaaatccttt
      781 tccaaaattt cacctcataa aatttattta aaacgcatca aatacaacta aagtaataaa
      841 taaaattaac tcttattaat gtgatatata taaacaataa atttagccat ttattattta
      901 tatatatcaa aaaattctat ctcaaacttt tcaatattat cattgtaatt tgaattatca
      961 tatacttctt caacaacctc tttaattggg aatataactt ttacattagt tccttctcct
     1021 accttactat ctatgtaaat cttcccattt tgaatttcaa tcaatgattt tgtaaggcat
     1081 aaacctatac cacttccaaa ttcatttgat ataccactgt tttcaatttg tttaaatcga
     1141 ttaaatatat catttaattt ttctttgtct atgcccactc cagtatcttt tataattatc
     1201 tctactgttt cgtctttttt atatatacct acaaggattt ctcctccttc taaagtaaat
     1261 tttatagcat ttgataatat atttagtatt attctttcta tagattctgg gtcaagccct
     1321 accataacag tttcttcatc cgtatcaaaa attaaatcta ttcctttaga cttagcataa
     1381 ctactaatag atgtaactat tctttctgtt atgtcaataa tatcaaaatt aactgcttta
     1441 atcttatata tgtctgactt aacttgagaa atatttatta tattatctat taatctcaat
     1501 aatctaaaca tattttgttt agttattttt atatgttctt ttagtatatc ctgaaaatca
     1561 attatttttc cttttttata aaggttttca ataagttgaa ctgaactata tatattattt
     1621 aaaggtgtct taagttcatg agatatatta gcataaaact ccatcttcat ttggtcatac
     1681 tgtctttgtt ttattaatgc ttttttaagt ctttcagact ctctttgcac acttaaatct
     1741 ttaataattc tcactctact tcttttctgt ccaaagtata atgttcttga tatcattttt
     1801 acttctttaa tgtgattatt ttcatttact atatggatac tcttctctct ttctcctata
     1861 tttaaattgt ttatgtattt ttttactaat atatttctat atttttgtgt tgtaactcct
     1921 aatacatcac tagaaattcc gaacaactct ctaaaggctc tatttgtata tagtactctt
     1981 gatgtactta aatcctcaag aaaaatagcc tctggtataa catcaagtaa tttttcatat
     2041 attatttttt gttcatttac tgttctaaga atatttatct ctttagttat atctctaaat
     2101 gtaagcaatt taaagagttt attatctgac caatagtctc caactctaac ttcttcaaca
     2161 tgttcttcac cttctgagtc agacatcaca aaattaacta tacagtttgc tgtgtcattg
     2221 taacttacta tttcagcttt cttttcttgt gttagattta atcttttaaa tttcctattg
     2281 tcaaagaaat ctatgttaaa agtttcaaaa tattgttcta atgtcatatc gactaaatca
     2341 cttgaaacac atttaaaact cttttcatat tttttattta tacttattac cttattcttc
     2401 tttatgccac cttcagcact tcttacaagt ataggagatg gaatatttag tataatgttt
     2461 tcatagtctt tatttatatt tcttatttct tcatctattt tgatttcatt tgtaatatca
     2521 tttaaactta ttaagtaatt gctttcatct ttattattac ttaaacttaa caaataaatt
     2581 ttatcattta actctaccag tttatcaatt atacttatat cgttatcaaa tttcttcaat
     2641 ttttcagcaa ctttttcatc ttcctttata aaagttaata ttttataata attattcata
     2701 tcctttgaaa attcatcttt aaatttatta tttgtgtaac ttatattaaa atcatagtct
     2761 gttactatcc atacatttgg tattgtatcc agagcttgtc taagtaattc ttttctctgg
     2821 tctatgtagt tttttaatgt tctttgtata atcatatcct tttctattgc taaatttatc
     2881 tttcctaatt gctctgactt tttacttaat tttttattga ttgaatcaag ttcataatat
     2941 ggatacacta ctctattatt aagactgtat acatatacat aataagtatg gttacataat
     3001 agtaaatata ttactcctat taatctatct gaatctacta tattaatctt agaaattgct
     3061 acaaaacata taatagttgt aaaaaaaaca aaatatgtta aatcttttat taacttatag
     3121 tgctcaatgt tactatcaag tttattcaac aaatatagta aattaaacat agatatacaa
     3181 atattaatta atataataat catattccag ttaatatcac taaaaatatt tcttataaag
     3241 taatctaata tcacaaaagc actataaaaa attagtattg ggcttattct tagttttttt
     3301 actttagaaa tggttaagta tataaaagta gacatattaa ttatgcttaa gttaagcaat
     3361 acaatttgga atttttgaat ttttaaattt actactccta aaatacttac aaaaactaat
     3421 acaagacacc ctactttcaa tatatttata aattcatctg ttttaaagct acttatataa
     3481 actatagaat atccaaatat ccaaagtaaa attattctat acatatttat agaaactgta
     3541 tacaaattta tatttaaaag tgcaataacc aaaaataacc cattagctag tatatagacc
     3601 ttattcttac ttaaagttcc tttagattcc atattcccca ccacttcttc atttttatat
     3661 agttttacct ataaatatgt taccacaatt cttccaaaaa atttgtcact ttctagttat
     3721 aaaaaaaaat gagtaaatat ttttaatttt actcattttg tagattttgt atattcagtt
     3781 taaaaagctg gaactatact tcctttatat tcatcttgta taaatttttt aacttcttta
     3841 ctattcatag cctctgataa agccttaatc ttatcactat ctttattatt ttctctacaa
     3901 gctattatat ttacatatgg agaatcactt gattctatta ctattgcatc cttagtagga
     3961 tttaagttag ctgttaaagc ataattagaa tttattactg ctccgtcaac atcttttaat
     4021 actgttggta attgctctgc attcatttct tttattacta tatttttagg atttttagtt
     4081 atatcttttt tagttataag ctctccatct tttacttcta tcaatttatt ttttgctaat
     4141 aatttaagtg ctctagctcc attagttgca tcatttggca cagctataac agctccatct
     4201 tttaattcat ctaatgactt aactttttct gaatagaatc ccattggctc tatatgaact
     4261 ttagatgtat aagtaagttt atatcctttc tccttcacag tttcctctaa aaatggaata
     4321 tgttgaaaga agttagcatc caaagaccct tcatctaaag ctgtatttgg aagtacataa
     4381 tcatcaaata tttttacttc taaatcatat cctttttctt ttaacaaagg ttttgcaact
     4441 tccaatatct ttgcatgtgg atttgatgaa gctcctacta gtattttttt atcctctttg
     4501 tttgaacaac ctactgctga tattgctatt gctgacacca atgctactga taataatttc
     4561 tttaatttca tttttactcc ccctctttaa aatgtttata attaatttat tttagtttct
     4621 tataagccag atttcctact ccctggatta tctgaactaa tattataagt gctattacag
     4681 tatataccat tactgctgta tcaaatcttt gatatccata aataagtgct atattaccta
     4741 atcctccagc tcctactgca cctgccatag ctgtataacc aagtatagat attattgata
     4801 atgtaattcc agatactatt gaaggcatag cttcctttat cataacttta aatactattt
     4861 gtctttttgt agctccaaaa gattttgctg cttctatcaa tcctttatca acttcattta
     4921 atgagctttc tataattcta gcgataaacg gtgctgcccc aatagttatt ggcactattg
     4981 cagcagtttc ccctatactt gttccaacga ttaatctagt tattggaatc attgcaacta
     5041 taagtatcat aaatgggaaa cttctaaata tatttactat aaatcctaat gcactattta
     5101 ttgtgctatt tggttttaat ccatctggtt ttgtaactac taatatgatt gctaatataa
     5161 atcctaatat tgttgccact atagttggta ctataaccat atacaaagtt tgtaacaatg
     5221 catttggaaa tagtgttgtt aaaaagtcaa ttaaactatt catttatcat ttcctcccat
     5281 cttatgccct tactagttag atattgtttt acgtgctctc cacttttatc tgaaatgttt
     5341 ataataagtg aacctaaaat atcatcttta aattgttcta atttcccaaa tattatagac
     5401 acatctatat ttagttctct tgccatagtc gtaataatag cttcattaga aatatcttta
     5461 gggaatagta tctttatatt tgttcctttt ggcaatatta tactttcttc acctattaat
     5521 tttctaagtc ctttagtatt tcttaagaat atttcttctg tatctcctac ctctaatact
     5581 tctccatttt ccattattgc tactcttcca caaatctgct ttataacttc catttgatga
     5641 gttacaacta ttattgttat tcccaatttt ttatttatat cttcaagcaa tgaaagaatt
     5701 gactttgtag tatttgggtc taatgctgaa gttgcttcat cacaaagaag tacttgtggg
     5761 tttagtgcta aagctctagc aattgcaacc ctttgttttt gtccgccact tagatttctg
     5821 ggtttatcat ttttcttttc agatattcca actacttcta ataactctaa aactcttttt
     5881 ttaatttctg cctttgagta tccaaaacat tctaatggca atgctacatt atcaaataca
     5941 gtttttcttt caagcaatga aaagtgttga aaaatcattc ctaactcttt tcttaaatct
     6001 ctcatttgct tttcattcaa tgactttact tctttatcag aaacaagtac actgccttct
     6061 tggtattctt ctaatccgtt tatacatctc agtagtgttg atttccctgc accactatga
     6121 cctattattc caaaaatttc tccagattct atttcaatac ttacatcttt aagcacttga
     6181 atctttccat aatacttatt aacatttttt atgctaatca taaaatttcc tcccatatat
     6241 tctgctcagt ttttatgttt atcctctctt atgtattaca acaaaataaa agcccgagta
     6301 taaactcagg cttagaaagc tatttatact catctatcaa ctatattagt tgcaggattt
     6361 agcaccaatg tatataaaat atactggttg ccgggtttca aagggccagt ccctccacca
     6421 ctcttgataa gacgttattt aattcaattc tattatcatt tgttgctatg ttatatatga
     6481 tatattcatt aatagtattt gtcaataaat ttatttaaat tttttatttt ttattatcgt
     6541 taattaacta tttttaatta gttttctagc tcctaacact ttatatttta atgtctatat
     6601 aactatagaa catcattata agaaataaat taaataacat caatctatct aaatcatctg
     6661 taaagtaaat taagaaaatt aacattttat ccaaactcta tcctactatt aaataaaata
     6721 atttaaatac aatgatgatt atatagctct aatactttag ac
//
LOCUS       DAEQJM010000121         6700 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.124, whole genome shotgun sequence.
ACCESSION   DAEQJM010000121 DAEQJM010000000
VERSION     DAEQJM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.124"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            429..1703
                     /locus_tag="KRQ43_003503"
     CDS             429..1703
                     /locus_tag="KRQ43_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH2743837.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSAIYVKNATEGINF
                     LAKFFKDENPDKFIITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGISPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1910..2227)
                     /gene="trxA"
                     /locus_tag="KRQ43_003504"
     CDS             complement(1910..2227)
                     /gene="trxA"
                     /locus_tag="KRQ43_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH2743838.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2494..3246
                     /locus_tag="KRQ43_003505"
     CDS             2494..3246
                     /locus_tag="KRQ43_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBH2743839.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKN
                     KSVEYVLNIKGDKNILKKALEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHTHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3233..4114
                     /locus_tag="KRQ43_003506"
     CDS             3233..4114
                     /locus_tag="KRQ43_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH2743840.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNVADFKVQFFTPGLEVDLCGHATIGTFHALLEEGRLNTNKSIFYQETK
                     AGVLSVELKEINNENIFMMEQNTPEFENLDNYRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4340..5695)
                     /locus_tag="KRQ43_003507"
     CDS             complement(4340..5695)
                     /locus_tag="KRQ43_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH2743841.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKVEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2574 a          959 c          834 g         2333 t
ORIGIN      
        1 ttatacttgt acatctttta taacatataa aatctttttt tctaattata tacaatatat
       61 tttccattat gttctaatca atttctttac tatttttaca actttattag tcatattcat
      121 aattatttct aattagtgtt taacatttta tgtaaaattt ataaaaaaat gtatataaat
      181 taaaataagt gactatacta aaaatatgat acggataaac aataagttca acctatctcc
      241 cccaaaatca agtgagctac agtttccccc aactgtagct cattttcgtg taatttaata
      301 aacatctcaa caagaattaa ttaacaaaac cccttataaa aacataacat atattaaaca
      361 agctcttgat taaaacttga gcttttttaa taaaaaacag aatagtttat tagataaggg
      421 gtttttttat gcaattcatg gatgtatcta aatacattga aggtgcaaac cttaaagtta
      481 aaactaaaaa tggtgaaact gttaaaagaa tatattttaa caactctgcc actccattag
      541 ttttaaaaaa cgtagtggat aacttaaact gtgagattcc ttggcttact tatattaatg
      601 ctccaggaat aatctcagaa aaaaatactt taaaatatga aaatgtacgc tctactatcc
      661 tcaaacttat tgatggagac gaagaaaagg attctgctat ttatgtcaaa aatgctacag
      721 aaggaataaa cttcttagca aaatttttta aagatgaaaa tccagataaa tttattatta
      781 ccacagcaat ggagcatatg gctaattacc taccttttaa agttaatttt cctacaaaag
      841 ttgttggaat tacagaaaaa ggagaacttg atttatgtca attagagaat atacttaaaa
      901 attatgctgg taatgtatct ctcgttacag ttacaggagc tagtaatgtc acaggtataa
      961 ccactcctat atatgaaata gcaagaatag ctcataagta tggtgcaaag atattggtgg
     1021 atattgtgca agtaattcag cataaacctt tttcaatgat gccacatgaa tgtgatgagc
     1081 atatagattt tgttgttttt agtgctcata aatgttattc tccactaaat ggaggagctc
     1141 tggtaggacc taaaaaattc tttgaaaaat ttaatcctgt actatatggc tcaggttcta
     1201 ccaaatttgt aaatgataac aaaatactat atgcaaacgt accccaacgt tttgaagcag
     1261 gatacccaga gtattttgga actcttgcaa tgggaaaagc actgaacact ttaaataaaa
     1321 ttggtctaaa cagaatttca aaatacgaaa gagaattatt tttatatgct aaagaagaaa
     1381 tgagtaaaat acctaatata ataatatatg gagataaatc aaataatgta attatcccaa
     1441 atatatcttt taatataagt aatatgtatt acaaagatgt agcaaaatat ttagttgata
     1501 actttggaat agaaactgga gctggagtag taggtgcaga tatttatgta caaaaattat
     1561 taggtataag tccaaaagaa gcatacgtca gatttatgag ggaaaatcct gtaggtcttg
     1621 ttaggataag cttaggaatg tacaatactt ttgatgaggt ggatagcttt atacatgcta
     1681 ttaaaacttt ggcttttaaa taagcttttt ctattctttt ttatcaataa atagagagta
     1741 gttttgtttt cacaaaaaaa caaattatat caacagtcaa tttcattagc aattagacac
     1801 tcatttgtaa ctatacaaac tattttacac tatacaaata aaaaactcat tacaatgagt
     1861 ttttttgttt atatatgata tttattttaa ttacttcaat ttactttaat tacatatatg
     1921 attcaatttt gttttttaaa ttctccttag gcataaaacc tattaatcta tctacaggtt
     1981 ttccatcctt aaatattagc atagttggta ctgtagatac ttcaaatttc tgagctaatt
     2041 ctatactttg gtctatatcc accttcaaga agtttgcttt ttcaaccatc tcatttccta
     2101 aagcttcata tattggtgat agcatcttac aaggtccaca ccaagtcgca aagaaatcta
     2161 caactactaa accatcttta ttttctactt catttataaa ttcattatta tttattattt
     2221 ttaccataat atacatctcc tttattatct tcttgatact aatatactac gccctatata
     2281 acagttcaat taggcacttt tttgtaaccg cctattttta atagatttaa tattatgata
     2341 aatagattta taagattaaa tatttataag actaaatatt tctgatatat tttatttttt
     2401 tcttaatata gttgacattt tctcccttaa attataaaat caaattaata actacatagg
     2461 tagttactaa tcttttatca aaggagtttc tatatggata atataattaa tgaattacaa
     2521 aatataggat ttactaaata cgaatctcaa atatacatat cattattaaa ggaaagccct
     2581 ttaacaggat atgaaataag taaattatca ggtgtaccac aatcaaaagt ctatgaaaat
     2641 ataacaaagc tattaaacaa taatataatt atcaatgttg gaactgaccc tattaagtac
     2701 atacccataa accctaatga attattaaaa aataagaaaa aagaatttga taattctatg
     2761 gataatctaa agaatagctt acagatatta aataaaaata aaagtgtaga atacgtttta
     2821 aacataaaag gagataaaaa tatattaaaa aaagcattag aaatgataaa aaatgcaaaa
     2881 caagaaatta taatttcttg cccttatgaa gaaattcttg aattaaaaaa agaactccta
     2941 attgcttaca aaaaaaatat taatattgaa atactacttt tagaaaacaa aagtctgaaa
     3001 ggtcttgata atattcatac tcatggaggt aataaaacta cacttgaaaa taaaatgctt
     3061 tacaaaggaa ttattttgat tgtagataat gatgaaatat tgacaggaaa cttatcagaa
     3121 ggcagtgagg ccatttcaat ttggacaaaa aactctaaca ttttatatat tggagttcaa
     3181 tacataaaac atgaaattta tatttcagaa caaataaaag gaggttataa aaatgaacaa
     3241 aattaagatt aaacaagttg atgcttttac aactatacct tttggtggaa atcctgctgg
     3301 tgtcgttact gatgcctcta acatttctga tgaaattaag cagaatgtgg ctaaagaaat
     3361 gaatttatca gaaactgcat ttgtttcaga gtcaaatgtt gcagatttta aggtacaatt
     3421 tttcacacca ggtttagaag ttgatttatg tggtcatgca acaataggta ctttccatgc
     3481 acttttggaa gaaggaaggc ttaatactaa taagagtata ttttatcaag aaacaaaagc
     3541 tggtgtatta tctgtagagc ttaaggaaat aaataatgaa aatatattta tgatggaaca
     3601 gaatacacct gaatttgaaa atttagataa ttacagaaaa gaacttgcac aaatgatagg
     3661 tgtgcatgaa gatagacttc ttgaatatcc tattataaag gtaaatactg gactttggtg
     3721 gcttgtattt ggtctaaaat ctttagatga tttaaaaaat atctctccag atttaaataa
     3781 aatcaaaaaa tttagtggtg ataataatat aattggtata actccatttt gtatagaaac
     3841 tatagataaa aagtgtgact accatttaag atctatagca ccatatgttg gagttacaga
     3901 agaccctgta tgtggaactg ggaacgcttg cgtatcatct tatatagtac atcacaatat
     3961 tttagataaa actagtttta ttggtgagca aggtaacttt ataaacagac ctggaaaggt
     4021 atatgtaaat ataactagag aaaacaatga cataacttct gtaaaaattg gaggaagtgc
     4081 ttatactgtt ttaagtggtg aaattatgta ttaatcccat acctaataaa aacaaataaa
     4141 aatactagct aactaaagct agtattttta tttgttattt ttatttaata atcacactct
     4201 aacaaatatt ataattatat atatcataat attgtattta gaagtaaaat tttattttta
     4261 ttattaatta gttataaatc aatctaatac aacataatta cagtagatta atctataaaa
     4321 cataataatt acttactgat tatttatcat cctcaacaag tctacttaat gtcttatcag
     4381 ataagaataa taatatcgct gcaacaaata gtattactgg aattatagta tatactttaa
     4441 tcatatcaaa tttaagagta aatgcatata tatatccata tcctttacca gctataaaag
     4501 tagcaaatgt ccatactccc ataagaacac ctagaagctt cttaggtgca tacttactta
     4561 caaaagagtt accaagtggt gagaataaca tttcaccaag acttaaaaga ataccaaaca
     4621 tgattatcca tagtatacta gctttagcag tttcaggagc tccaactcct cttgaaaatt
     4681 ctgcaccaac aagcattaag aatgcaagac ctaagaatat taatccaaga cctgtctttt
     4741 taaataaact catatctcct tgtggtctac tagcaagttt aaaccataat gctccaagaa
     4801 ctggtcctaa tactatacat acaagtgaat ttaatgagtc aaaccaagca agaggaacat
     4861 caaatcctcc aacattcatg tttacaaatg ctgcaccata atcataaact gcaagataag
     4921 ttagatacca gaatacccag aaaattacag agaagaatga tataagtata atagcccaaa
     4981 ttctcttctt atccatgctt gtaagaggag acttatcttt ttcttcaact ttttcagcaa
     5041 ctacaccttc tttaaaaggt ctctttcctg catttccaag gaatctccat ccatatatga
     5101 accatattgc acctattaca caaagtacag ctgctataaa gaaacattga gaaaatccaa
     5161 gtacaccatt ttttgcaaat gttttaaggt aaagaatacc aactgctata gtaccaataa
     5221 aagaacctat attaacaaaa gaatattgta ctgaaaatgc tgtatcaagt tcttcttgac
     5281 tatcaaaaag ctgtccattt accgcagata cgttaccttt aaagaatgca gtaccaatcg
     5341 aaactaagat tatcattgca tttaccatag aaactgtagt tgcaatagaa ccaagatagt
     5401 aacctacccc catgataagc atacctatag gtatagtata tctagctcct atccatctat
     5461 ctgatatata tcccccaatt ataggtgcaa ggtatgtgaa tgcaacaagg ttggcttgca
     5521 ttatagcagc ttgtccttta tctattccaa gaccaccatg aactatagct gttgtaagga
     5581 atatatatat taagtacttt gaagcataat atgctgctct ttcaaatgag aaagttgttg
     5641 agcagatata aaatcccata ggaaatttac ccttcttttt tactgttgag ctcataattt
     5701 taaatccttt cttaattgta tttttatttt ttacgttttg tccaaattct ttcttttatg
     5761 aaagatataa tattattatt ttgtaaaaca atttgtaatt attattaaga taattgcgca
     5821 tttatttgta gagtacatat tctcatggaa taaaattaat acacttctta atcataaatt
     5881 taaattatat aaattcacta ttttcagata tagttataaa ttaatatatt ctcatctaat
     5941 accatgaaaa aaccttcgcc atatgcaatt cttatttttt acgtgatagt attttacaaa
     6001 ctaaaatccc ccttttgtag caacttctgt aattacattt tagtgctttt ttaaaggagt
     6061 ctcgaataaa gcaacatata ttttgttcaa ataatgtttt tatttacttt ttaaatttat
     6121 atattacttc actcaaccaa ttctcaactt aaataaataa actactatct attcacagat
     6181 tagacctatt tcttacacat tagtttataa taaacactgt gaatctaaac ataaaaactg
     6241 ttattttaaa gtaattaccc atatattcgc tttgatacta tttattgagg ttatactctt
     6301 tatttataat atattattta taaaatacct caaaatatat tattaataaa atacctcaaa
     6361 ctgaaaactt tttcacgaat atttattttt cacctcccct tttttatttt accatgtaaa
     6421 tcgtaccata aatatgcact tatatgcaag aaaaaaatct attaatcgac agtaaataat
     6481 tagaaaaatt taaattatat ttgttaagtg tattatataa aatatttcct atgaaaatat
     6541 aaattaaatt aatgttcaga atagttttta gatatgaaat cttgattttt ttattacttt
     6601 acttatttgc tcaaatatat ttttgtatgc agtatataat aatcaaatta tacacttctt
     6661 ataactgcgt tgatttgaaa ataatattaa tagttaatag
//
LOCUS       DAEQJM010000122         6646 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.125, whole genome shotgun sequence.
ACCESSION   DAEQJM010000122 DAEQJM010000000
VERSION     DAEQJM010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6646
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.125"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            369..1283
                     /gene="queG"
                     /locus_tag="KRQ43_003508"
     CDS             369..1283
                     /gene="queG"
                     /locus_tag="KRQ43_003508"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBH2743842.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFVDNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEMPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            1389..3626
                     /locus_tag="KRQ43_003509"
     CDS             1389..3626
                     /locus_tag="KRQ43_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2743843.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNRLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDKSDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNESSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            3823..4875
                     /gene="nth"
                     /locus_tag="KRQ43_003510"
     CDS             3823..4875
                     /gene="nth"
                     /locus_tag="KRQ43_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBH2743844.1"
                     /translation="MKNVNLKEINEKDVIVEEDINLKGMDKKDVIEKEEVNKKSIDKK
                     DIIEKEEIDKKNVKKVEVQKEIDKMISKKDEIIDEKDIENFRYIEEDKKSIKVSKKST
                     KKGETEKKTKKSSSNKATQKQSKEVKSKSKIKSESANKKDVNKILDELEKLYPDAKCE
                     LNYGTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGL
                     YKSKSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDT
                     HVFRVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASC
                     PIKEDCNYYKELNETK"
     gene            5069..5539
                     /gene="trmL"
                     /locus_tag="KRQ43_003511"
     CDS             5069..5539
                     /gene="trmL"
                     /locus_tag="KRQ43_003511"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBH2743845.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            5575..6423
                     /locus_tag="KRQ43_003512"
     CDS             5575..6423
                     /locus_tag="KRQ43_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH2743846.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVDEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
BASE COUNT         2822 a          580 c         1264 g         1980 t
ORIGIN      
        1 ataaaaaaga ctaagtattc aaaagagtta gtaggtaaaa taattaaata gataaaaaga
       61 ctaagtattt aaaggagtta agcagataaa aaagttaaat aagtaaatga aaaagacgaa
      121 gtatctaaaa gagttagtaa ataaaaaagt taaataagta aataaaaaag atgaagtatc
      181 taaaagagtt agtaggtaaa aaactaaata ggtaaaaaga cgaagtatct aaaagagtta
      241 gtaggtaaaa aagttaaata aataaaaaag acgaagtatt taaaagagtt agtagctaga
      301 aaaggttaaa aagactaaaa aaattaaata aatttaaaaa gtcaattaga ttaaaaagga
      361 ataattttat ggataataag gaattaaaag cattttgtaa tttaatagga ttaaactgtg
      421 taggagtagc aggggtagat aagtatgata atttagaaaa gatacttaag gacagacaac
      481 aaaaaggtta tttaactggt atggaagaac caataattga gaacagaatt aacccaagac
      541 atataatgaa ggatgctaac tctataatag tctgtgcatt tccatatcat ataaatagac
      601 aagaaaagaa taaaaattca aatttatcaa aatattgtca tggaaaggat tatcacattg
      661 tagtaaagga ctttttacaa caaatttgtg attatatttc taaaacagta acagatttta
      721 aatacaagtt atttgttgat aatggaccat tagttgacag gtatttagct tatttatcag
      781 gaataggata ttttggaata aataataata tcataactga tgaatatggt tcttacgtat
      841 ttatagggta tatagtaaat aattataaat ttgaagaaga taaaccacta gaaaaaagtt
      901 gttttaaatg tggtaagtgt gtaaaatatt gtccgggaaa tgctatattg ggaaattatg
      961 atatgaaccc caaaaaatgt ttatcatata taactcaaaa aaaaggagat ttgtcagaga
     1021 aagaaaaagt tgttttaaag aatggcaaaa aggtatttgg atgcgatatt tgtcaagaag
     1081 tatgtccaca taatgttgaa atgccaacaa ctcatatttt ggaatttaaa gaaaatataa
     1141 tagattattt ggattatgat gagatacaaa atatttcaaa taaagaattt aaaaggagat
     1201 atggagatag agcttttagc tggagaggga gaaatataat aaagagaaat atggaaataa
     1261 ttttagataa gtatgatgac taataataag agtctgtttc atatacttta atgtgtattt
     1321 actttaacac ttgttgtgta aaagtcatat tatatcatta aagttaaata tggggaggtg
     1381 ggggaatatt gaaatataat aatacatctg aaataaatcc actagattat atattgggtc
     1441 aagaaagagc tgtagaagct atggaattag ggttgaaaat aaataatcca gcgtacaaca
     1501 tatatatagc tggtgaacct ggaactggta aaagtactta tgccttaaag gttttaaatg
     1561 aatatgcatc caaaaaaaat acacataaag attggtgtta tatatataat tttgaaaacc
     1621 ctagagagcc tattatagtt gaattagaaa aggggtttgg aagagaactt aagaaagata
     1681 tggagaaatt aattgaaagt cttttagaag attttaaaaa tgcgtttgaa agtgaaaatt
     1741 ttgaaataga aaaaaataga cttctagatg aatatgaaat agaaaaagat atgcttttga
     1801 agcaaattaa gaaatatggg gaagaaaaag gatttaaatt aaaacagagt aaaatgggaa
     1861 tagtttttat ccctttgaaa gaagaggaag atgaaagtga taagtctgat gaagagtttt
     1921 acaaagctaa aagagaacta gaaaatatgg cgatacaggt cgtatataaa attagaaact
     1981 tagaagaaat agctgaaaaa gcagtgttag agcttgaaga agagatagct aaacttgtag
     2041 tagaacctca tatcaagaga ttgtgtgaaa aatatgaaaa ttatgataag attcaaactt
     2101 atctggaaaa tataaagaaa gatataatag aatatatgta tttgttctat ttagatgaag
     2161 aggagttaaa agataagtat gataaagagc attttattaa atacaaaatt aacctatttg
     2221 tagacaatga aagctcaaag aataaagaat cagcacctgt tgtagtagag ataaacccaa
     2281 gtccagcaaa tctatttgga aaggcagagt atgattatgc aaatggaaat ataaagactg
     2341 atttcacaaa actattatca ggagcatttc atagggctaa tggtggttat ttagtacttt
     2401 atgcagacca attactaaaa tatacaatgt cttgggaaat tcttaaaaag actttgcaga
     2461 ctaaaaaagt aatattggaa acacaaacag caattaaacc agaaaatatg ccattggatg
     2521 ttaaattagt actgattgga agccactata tatatgatat tttatataga tatgatgaag
     2581 attttgaaaa atattttaaa gtatttgtag actttgatag tgaaatggat aaaaatgaag
     2641 ataatgaaga aggaatagca agatttatag cataccaatg tgataagaat aatttaaggc
     2701 attttactaa atcagcagtt gaagaggtta ttaaatttag cactagatta tctggtgatt
     2761 tagaaaaact atcaactaag tttaataaaa taatggaagt tgtaatagaa ggaagtgctt
     2821 atgcagagtt tagaaattcg gagtatacag agcagtgtga tgttaaaaaa gcaataagtg
     2881 aaaagagaaa aagaatcaat agagtggaaa cacatatgga tgaatcaatt gaaaatggat
     2941 ttactctaat agaaacagag ggaagaaaag taggagtgat aaatggtctg tcagtcttaa
     3001 gtacaggaga atactctttt ggtagagctt caaggattac agcgaccact agcccaggaa
     3061 gtaaaggcat agtaaatata gaaagagaag taaatatgag tggctctata cataacaaag
     3121 gagtgcttat attaggtggc tatctttctg agaattttgc acaggattta ctattgtcac
     3181 taaacgcata tgtttgtttt gaacaaaatt atggtggaat agatggagat agtgcatctt
     3241 ctgcagaatt atatgtacta ttatcatctc ttagtggagt atcaattaaa caaaatattg
     3301 ctgttacagg ttctataaat caaaagggtg atatacaagt agttggtggt ataagtgaaa
     3361 agatagaagg attttattct atatgtaaaa ctaaagggtt aaatggtgag caaggcgtca
     3421 taattcctag aaaaaatcaa agaaatctcg ttttatcaga tgaagttaat gatgcagtgc
     3481 gagatggaaa atttaagata tatactgttg aaagagtaga agaggctata gagatattga
     3541 cagatgttaa atttgaagaa ataaagaaat tggtaaaaga aaaattaata tctttcagca
     3601 agatacaaac tgtgtcaaaa gaataagttt attatagaat ttaatgggta tttatgtata
     3661 ataaaaagca agaactttaa taggtttttg ctttttttgt aaatatatat aaattaaatt
     3721 cttattttgt atgttttata tattgatgtt tattttttgt tgatatgact aaactattta
     3781 taaatagtgt tttataaatt ggtattttaa agggggataa ttatgaaaaa tgtaaatcta
     3841 aaagagataa atgaaaaaga tgtaattgtg gaagaagata taaatctaaa aggaatggat
     3901 aagaaagatg taattgagaa ggaagaagta aataaaaaaa gtatagataa gaaagatata
     3961 attgagaaag aagagataga taaaaaaaat gtaaagaagg ttgaggttca aaaagaaata
     4021 gataaaatga ttagtaaaaa agatgagata attgatgaga aagatataga gaattttagg
     4081 tatattgaag aagataaaaa aagtatcaaa gtaagtaaaa aaagtactaa aaaaggtgaa
     4141 acggagaaaa aaacaaagaa aagtagttct aataaggcta cacaaaaaca aagcaaagaa
     4201 gttaaaagta agtctaaaat taaaagtgaa tcagccaata aaaaagatgt aaataagatt
     4261 ttagatgagt tggaaaaatt gtacccagat gctaaatgtg agttaaatta tgggacagcc
     4321 tttgaacttt taatagcaac tattttatca gcacaatgta ctgatgtaag agtgaataaa
     4381 gttacttcag agttgtttaa aaagtacaac acagctagag actttgctaa tttgagcatt
     4441 gaagaaatta gtaaagagat aaagagttgt ggtctttaca aaagcaagtc tcaaaaaata
     4501 aaggatacat ctgaacagct atgtgaatta tatgatggtg aagtacctga tagcttagaa
     4561 aagcttataa aattacctgg tgttggaaga aaaacggcag gggttgtact tagtaacgct
     4621 tttaatcatc cagcaatagc tgtagatact catgtattta gagttagcaa tagaatagga
     4681 atagtggacg agccaaatcc tcaaaaaaca gaatttgcac ttatggaagc tataccaaaa
     4741 gaaagatggt cacactcaca tcatgtatta atttttcatg gaagaagaat gtgtaaagct
     4801 agaaatccag aatgtgcaag ttgcccaata aaagaagatt gtaattatta taaagaactt
     4861 aatgaaacga aataactttt agaaagtaag ttgtacaaga gggattttct gatataataa
     4921 tacttgtgaa aatgttagat aaaaaactat tatatacatg aaataaaaat tattattaac
     4981 attattttat ataatagtat aatattattg ttattctgtt tataaaataa aatttgataa
     5041 ataaaagcga tacttaggga ggattaaaat gtcattaaat atagtattag tagaaccaga
     5101 aatacctcaa aatacaggaa atataataag aacctgtgca gcaacaggtt caactttaca
     5161 tttagtaaaa ccactgggtt tttcattgga tgataaacac ctaaaaagat gtgggcttga
     5221 ctattgggat atagctgata tacaatatta cgatagcttt gaagaattac aagaaaagta
     5281 tccaaatagt aaatactttt tttctacaac aaaggctaaa cagtcacatt cagatgtgaa
     5341 atatgaagaa aattgtttta tagtatttgg gaaagaaaca aagggattac cagaaccttt
     5401 gttgaaagca aatatggata cttgtattag agtgcctatg ttggatgttg aaaaggctag
     5461 gtcattaaat ttatcaaatt cagttgctat tgtagtgtac gaggctttaa gacaaatagg
     5521 atacccaaat atgaggtagt ttcaacaagc ctaaatgaga aaggagcata cttaatgaaa
     5581 aatctaaaga taatctgtga cagtttatcg gacgtgccaa aagatttgtt agataaatat
     5641 gatatagata tagtttcatt aacagttata ctggaggaaa gagaatacaa ggatagaatt
     5701 gatatatctg gagatgaatt ttataaaagg cttagagaag aaaatgtata tccaaaaact
     5761 tctcaagcta cttatgccca atttaaggaa atttttgaga aatatacaaa tgaggataga
     5821 gagatacttt atatagcagg gtctgccaca gctacaggga cgtatcaaag tgctgtaatg
     5881 gcaaagaatg atgtggatgg taaaatatat acatatgact ctaacttgct ttgtatggga
     5941 actggtttac ttgtaataaa agcaggagaa cttgcaagtg aaggaaagtc tgttgatgaa
     6001 atattacctg ttttggatga attaaaagag aaggcttttg ttatattttc agtagataca
     6061 ttggaatatt tacaaaaggg aggtagaata tcatctacta aggcagcaat aggaagtata
     6121 ttaaatataa aaccgattct tgaaataaga gatggactag tttcgcaaat atctcaagta
     6181 agaggaaaga agaatgtaat ttctaagatg atggaattga taaaatcaaa ttgtggggat
     6241 gatttatcag accaaattgt gtatatagga tatagtgatg attttaagga aaaagaacaa
     6301 ttatctaagg ttatgcaaga tgaattaaga cctaaagaaa ttagattttt ccaaattggt
     6361 gtgtgtatag gtgcgcatgc tggtcctggt gtcactggta tcatatgctt aaaaaataaa
     6421 taatatattt ttggatgaca ttatttattt ttttattaaa ttaggataga atattaatta
     6481 ttgagatgtt aaattggatt tattttggat gaaattaagt gttgatatat tagatttagt
     6541 ttgtagggaa gtgtgtaaat agataagaat ctattgcaca cttttttata gtaagattta
     6601 ttaaaaaaat ttcaaaatgt acttgtaaat tgtatataaa aaaatt
//
LOCUS       DAEQJM010000123         6476 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.126, whole genome shotgun sequence.
ACCESSION   DAEQJM010000123 DAEQJM010000000
VERSION     DAEQJM010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6476
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.126"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            170..313
                     /locus_tag="KRQ43_003513"
     CDS             170..313
                     /locus_tag="KRQ43_003513"
                     /inference="COORDINATES: protein motif:HMM:NF014609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH2743847.1"
                     /translation="MNKKFRLYQVDSFTKERFTGNPAGVITNADGLSESQMQKITREL
                     NNS"
     gene            335..1090
                     /locus_tag="KRQ43_003514"
     CDS             335..1090
                     /locus_tag="KRQ43_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis isomerase"
                     /protein_id="HBH2743848.1"
                     /translation="MAKNHQENYDVHIRFFTPTNEVPICGHATIAAHYVRAVENQFNN
                     KTVFQKTGAGILPVDIIKKDNDYEIIMTQGKIEVSPPLQQTYQKRLLNAFGILNEDIR
                     TDCPIAISSTGHSKVMIGIKELSTLNSLSPNLYELSKISQEIKCNGYYIFTLHNKETL
                     QVHGRMFAPAIGISEDPVTGNANGPLGAYLVHYKVIPIPNTEFIFEAVQGEAIKRKGK
                     MLVKVIISDNKPVEVKIIGKAVIAFSTNIEIEL"
     gene            1315..1926
                     /locus_tag="KRQ43_003515"
     CDS             1315..1926
                     /locus_tag="KRQ43_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBH2743849.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIIEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            2224..2562
                     /locus_tag="KRQ43_003516"
     CDS             2224..2562
                     /locus_tag="KRQ43_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH2743850.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(2969..4405)
                     /gene="miaB"
                     /locus_tag="KRQ43_003517"
     CDS             complement(2969..4405)
                     /gene="miaB"
                     /locus_tag="KRQ43_003517"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBH2743851.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
     gene            complement(4653..6089)
                     /locus_tag="KRQ43_003518"
     CDS             complement(4653..6089)
                     /locus_tag="KRQ43_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HBH2743852.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPIVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT         2285 a          935 c          707 g         2549 t
ORIGIN      
        1 tagcatagag ccttacataa tactactttt ttagatgtat atttttaaat tttaatatag
       61 acatatgtta ttttattaat tttatttaaa cagataataa taaataataa tttatctcaa
      121 gttttctatg tagataaact aatctaatgt ttagaaagga ttatataata tgaataaaaa
      181 atttcgtctt tatcaagttg actcatttac aaaagaaaga ttcacaggta atccagctgg
      241 tgtaattaca aatgctgatg gcttatctga atcacaaatg caaaaaataa caagagaatt
      301 aaataattca taaactgctt ttattttcaa taaattggct aaaaatcatc aagaaaatta
      361 tgatgtacat atcagatttt ttacaccaac taatgaagtt cctatatgtg gtcatgctac
      421 tattgctgcc cattatgtta gagcagtaga aaaccaattc aataacaaaa cagtatttca
      481 aaaaactggt gctggaatat taccagttga tattataaaa aaagataatg attatgaaat
      541 aattatgaca caaggaaaaa ttgaagtatc tccaccatta caacaaacct atcaaaaaag
      601 attacttaat gcatttggta ttttaaatga agatattcgt acagattgtc ctattgccat
      661 atcatctaca ggacattcaa aagttatgat tggaataaag gaattatcaa cattaaatag
      721 tttatctcca aatttatatg aattatcgaa aataagtcaa gaaataaaat gtaatggata
      781 ttatattttt acattacata ataaagaaac tctacaagtt catggaagaa tgtttgctcc
      841 tgcaattggt atttcagaag accctgttac aggaaatgct aatggacctt taggtgcgta
      901 ccttgtacat tataaagtaa tacctatacc caacacagag tttatatttg aagcagttca
      961 aggagaagca ataaaacgca aaggcaagat gttagtaaaa gtaattattt cagataataa
     1021 gccagttgaa gtaaaaataa ttggaaaagc tgtaattgca ttctcaacaa acatagaaat
     1081 cgaattatag attctttcta agtaaatttt tgaacttttt aatactaatt taataacaaa
     1141 ctaatttata tacaatcaaa ttaatttttt tattatttgt taatatatat ttatcattat
     1201 attatataat aatatagata gttactatat cttataatta gataaatcat aattatatat
     1261 tattgttaaa actcaattat ataattttta ataatattat tttaggaggt aaaaatgata
     1321 aacgatatta aaaataaatt caaaaattac aaaccatata taaatggata caagaatatg
     1381 aagagagcat ctgttttaat tccaataata gaaataaata acacacacta tatattattt
     1441 gaagttcgct caaaaaattt gaagcatcaa cctagcgaaa tttcttttcc aggtggtaaa
     1501 atagaatcag gtgagactcc atatgaagct gttattagag aaacttgtga ggaacttgga
     1561 acttttagtg acaatataga agtaatatca agtcttgacc tccttataac accagtaaag
     1621 tttatcatac atccatactt aggatatata aaaaatatta ataatttaaa tataaacaag
     1681 gatgaagttg accatacttt tttggttcct ataaaatatc ttttagagaa tcctccaaat
     1741 acttatagta atactgtaaa agtttttcca gatgaaaatc taccatatgg ttcaattcca
     1801 aaccaaaaag attataaatt tgaaagtgga agttatccta ttctgtttta taaatataaa
     1861 gattatgtaa tttggggaat gacagcaaaa atactagaaa actttttaaa ttttttatca
     1921 gaataacact cataataaat catcaaaact tttacataag aaatttataa aagtttctaa
     1981 atttaacaat tctaaaatat caataactat attttgtagc acttttttat tttattattg
     2041 tttgaatatt tgatggtttt caatgcaatt tcaacataaa tactatgtat tagtgtatac
     2101 tgttgatgaa ttaaagtatg ataatctatt taataaagta tgaagtaaat gattttaatg
     2161 tgtctttatg gtaaaattac taataagtaa taaaattaat taaaatatat ggaggtgctt
     2221 ataatgtttg ctgtaggatt tgttgttata attgcacttg cctttttcat tttaagtgta
     2281 ctattattta atggaaaagc cagtatgcta ctagcaggtt ataactctat gagtaagaaa
     2341 gaaaaagcac gatacgataa aaaaaaatta tgtagaagtt ctagcattgt tacttttatt
     2401 gtctctataa tgctatttat tatggcattt ttgggatata gaatagagag tggtcaaatg
     2461 gacgaaaaaa aaatggttcc cttttctata atatttataa tagtcatact ttccagtgta
     2521 ttttttaata tcctctactc taacaaaaaa tgtaaaaaat aaatagttgt aagttgagca
     2581 gttaattata aaagattgac tgctttttca tgtatattga ctactcttat taaatatttt
     2641 aacatttaaa aatctatgta aaaataatga atatagtaca aacttctaat aatgatttta
     2701 cctttgtggt tacagtccac tatatataat ttaatatgat aacatggaat tactaatgac
     2761 aactaagtaa gcttttataa aatataataa aacaaaaata gatgtacaat gaaattatat
     2821 cttatatcaa atttattttt attaatagca aaaacttaca ttagcataac atatgacaaa
     2881 ttcgcttaaa ataaaaattt ttaatataat ttgttctata gtacatctat ttcgattagt
     2941 ttacataatt ttattatttt gtacaatatt aattatttac taatatccca tttaatgaaa
     3001 aagttctagg ttcagtaatt ttgaccataa ctaatttacc aattaaatca tcatttccac
     3061 cttcgaaatt tacgagttta ttttgtctag ttctaccagc aaacttattt tcattatttt
     3121 tacttcttcc ttcaactaga acttcaacta ttctatcttt atatccatca tttatttctg
     3181 cagaaatcct atttacagct tctaacaccc tattaaatct atcatgcttt atatcttctg
     3241 gtatttgatt ttccatttta gcagcaggag ttccctgtct tttagaataa ataaatgtaa
     3301 aagctgaatc atatctaact ttttcaacca catctaaagt gtccaataaa tcttcttctg
     3361 tttctcctgg gaaaccaatc attaagtctg tagaaaaagc aatacctgga acttcctttt
     3421 tagctttttc tattatttct aaataatatt cctttgtata atgtctattc atttttttca
     3481 aaaggctact gcttccacat tgtattggta gatgtaaaaa ctcacacacc ttatcacaat
     3541 ctctaattgc gtatattact tcatcagata tatcttttgg atgagatgtc ataaatcgaa
     3601 ccctttcaat tccttctata tcattcactt ttcttaaaag ttctgagaat gaaactggat
     3661 tttcaagtgt cttaccataa gaatctacat tttgtccaag taaagtgatt tctttcgttc
     3721 catttgcaac aagctctttt atctcgttaa ttatatcttc aggagttcta cttctttctc
     3781 ttcctcttgt gtatgggact atacaatatg tgcagaaatt attgcatcca tacattatat
     3841 ttacaaatgc ttttaattca aattttctat tacttctaag accttctatt acttctccat
     3901 ccacatccca tacatccact aacattttgt cagaatttat tgattctgta agtaattgcg
     3961 gaaatttata tagattatgt gttccaaata taaggtctac atgtttatat ttttttctta
     4021 attcctctac aacatgtggt tgttgcatca tacatccaca tacagctatt ttcatatctg
     4081 gattttttcc ttttagatgt tttaattgtc ctaagttacc atacactttt agctctgcat
     4141 tttctctaac tgcacaggtg ttatatatta ttaaatcact ttcttcaacc atcattgaca
     4201 tttggtatcc catctcttct aacatcgaac ataatttttc tgaatcatgt tcattcattt
     4261 gacacccaaa ggtttgagta aacacgagtt ttctctttcc agttctgttg aagtattctt
     4321 cattttgtct gtgtatttgt tctatatatt tatcttgttc ttgtattttc tctataggta
     4381 ttgttacttg ttttcttttg ctcacgtcta ttcctcctag ttaatttctt atattacaca
     4441 taaccttaat tatatcaaat aagaaaaatc ttttaaagat attattattt ttctagttgt
     4501 gttttaatag taaatctaat gatttatata tactatattt ctaaaatata aaatcatata
     4561 attattataa taataaaaag atgttttaaa ttaaaactta aaacatcttt ccttaaataa
     4621 aatatatgat ttactattaa atacaattac atctattcat tttcaattaa ataacaatca
     4681 tttaatatta aatattgacc ttcctcaacc gttatatatc ttcttcctga aaaagtatca
     4741 ttagtaacta ttccctctgc attacctaag ctatcatttc taacttcata atatgcatca
     4801 gaagaatttg acattataat atattctcca gcaggaattt ctaatccaat tttatacata
     4861 ccatttccaa acttaccatt cttggccttc tgggctttag catactttgc taatgtcatt
     4921 gttgaatcct caattttaat atattgacca ttctttaagg tgatatatct agtcccacta
     4981 aaaatatcat ttgaaagtat actatcagca ttacctgtac tatcacttgt aacttcataa
     5041 taagaagcat aacttcctga gtttgaagta attaagtatt cacctgctga tatatctttt
     5101 ccaaccttat acattccatc ttttatagtc tttgtagtag gtttaacatt ttttacaacc
     5161 ccagtattaa tatctccaat tccatttgtt atatttaaac actgttgtac tatatttgaa
     5221 tctatatatc ctatagaagt tatcttctta gcatttttta aaatgctttt attgctacca
     5281 tcattaacta aaactattgg accatgtttt gataaagaag atcctacaag tgcatttgtt
     5341 aattcataag ctccagctat ataaaactct ctagcatcct tataaaactt atttattatt
     5401 gctttattag tttcaaaacg agtactccct cctagtctag tagatttagt attgtttact
     5461 aaagtggtac tcattgaagc tgttcctcct attacataag actttaaacc actagttgaa
     5521 aaaggtatac tttgtccatt agtaagaatt attggtgctt tatctcttgc tgctacagat
     5581 gcaatactta tagcatctgc ttctccttta tatgcattgg ttagcataac agtattgact
     5641 ttttttattg aatttatttc ttttgcaaca ttataacttg tttttattct gtcatttccc
     5701 ttaattctta caactttcat tttcttagat tttaatgaat tttcgacaga tgtactaata
     5761 gaatatgttc ctccaattat ataaactttt gatacatttt ttaatcttgc agatgtctca
     5821 gttggtatag tatttttttc agttaatagt ataggggcat ttaaagctcc tgctagtcca
     5881 cttgcactta atccatctgc aatagagtta ctagtattaa ttaatatagc agttttatat
     5941 gcatttttat ctgctatttt gcctgctatt tcatacttat tttttccttg tattttttct
     6001 acagatgata ttgcatctac taattgaata tttgcaaata caaaagaaat acttaaagtc
     6061 aatgttaata ttcttttata gaatttcata ataaaattgt ccccctcata ataaattttt
     6121 aatatataaa tacatattct taaattagtt atgtacttaa caaacttatg taaaattgca
     6181 aattatatta agcatattac aaataaatat taatacaatt attcatttag ctataattgt
     6241 atttacattt atattaaaaa tcaactagat ttgtataaat acttataatt atatttttat
     6301 tcttaatatt ttttttatta tgttatttta atagatttat ttttcttttt taagcataga
     6361 gatgtatttt tccatatatt ctatttctat tatagtttcg cttatttaat tcacccaaaa
     6421 tttcacttaa tattagaatt ttaaatcttt tactaaaaca gacttttata gttcta
//
LOCUS       DAEQJM010000124         6470 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.127, whole genome shotgun sequence.
ACCESSION   DAEQJM010000124 DAEQJM010000000
VERSION     DAEQJM010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6470
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.127"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            288..1232
                     /locus_tag="KRQ43_003519"
     CDS             288..1232
                     /locus_tag="KRQ43_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HBH2743853.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1254..1880
                     /locus_tag="KRQ43_003520"
     CDS             1254..1880
                     /locus_tag="KRQ43_003520"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBH2743854.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1914..2963
                     /gene="hisC"
                     /locus_tag="KRQ43_003521"
     CDS             1914..2963
                     /gene="hisC"
                     /locus_tag="KRQ43_003521"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH2743855.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2966..3544
                     /gene="hisB"
                     /locus_tag="KRQ43_003522"
     CDS             2966..3544
                     /gene="hisB"
                     /locus_tag="KRQ43_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HBH2743856.1"
                     /translation="MRIWKVERNTFETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3546..4151
                     /gene="hisH"
                     /locus_tag="KRQ43_003523"
     CDS             3546..4151
                     /gene="hisH"
                     /locus_tag="KRQ43_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBH2743857.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDITLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELVAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4148..4870
                     /gene="hisA"
                     /locus_tag="KRQ43_003524"
     CDS             4148..4870
                     /gene="hisA"
                     /locus_tag="KRQ43_003524"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBH2743858.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGINTKIIEDIANNIDIPIQVGGGVRDKGKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSDVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4852..5610
                     /gene="hisF"
                     /locus_tag="KRQ43_003525"
     CDS             4852..5610
                     /gene="hisF"
                     /locus_tag="KRQ43_003525"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBH2743859.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKNMGVEVRL"
     gene            5638..6306
                     /locus_tag="KRQ43_003526"
     CDS             5638..6306
                     /locus_tag="KRQ43_003526"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBH2743860.1"
                     /translation="MDNKCNNVYSDEVEEFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQKLWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMEPEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2639 a          542 c         1268 g         2021 t
ORIGIN      
        1 tttagaatat taataaaaat tatttgggag gaaattatca tggtgagatt aaatatagta
       61 aaattaaata caaaattaaa tcatcaccat catcatagat taaagggatt gtaatatgaa
      121 attaattcat agacacaagc cctgttttta gtgtaattgg tcttgtatct atgatgggaa
      181 gtaattttag gagaaaatta tagccatata ggtataaagc ctatatggct tttttattgt
      241 tttaaatttg caaatataag agtaaattta atgaagaggg tgagaatgtg aaatttttga
      301 ggattgaaga tgaagttatt tattctaaaa aaagatataa attaaaaagg gaaatagata
      361 aacttttttt ggatgaagaa tattttcaaa tagaaccaca attatttgaa gaatatgatg
      421 aatttacaac tataaataat aaaattccag aagaatctat ggtaaaggtt gtaaatggaa
      481 aagtaatggt acttagagct gatataacta caagtataat aaaaagcctt gtaccaagat
      541 gggaagatgg tttaaagctt aagctttttt ataattcatc aatatataaa aataaaaata
      601 cagttggaat aaaagagata agacaaatag gttgcgagta tctaggagaa gcctctgtag
      661 aagcagatag agaagtagtg aaattagctc ttaagatact tgaaaaatac aataataatt
      721 ttattttaga ggttgggagt agcaagtata ttcatggttt gttagaagaa ttaaatttaa
      781 ataagaattg tgaaaatcaa attaaaaatt tactatatac gaagaacact catgaattaa
      841 aagtatatat tgaagaactg aaaattaagc gtgaagtaaa agagctatta tcaaatattt
      901 taagcttgca agggaattta tacaacgtta ttgaaaaatc aaacaagttc tattgtaata
      961 ataagatgaa gcaagctctt gaagaattaa agcaagtaaa taatttaatt gaggaatgta
     1021 attttttaga taaggctaga tttgatttat caatgattac tatgcttgac tattatgaag
     1081 gaattatgtt tagaggatac tacccaaact catataaaga aattcttagt ggtggaagat
     1141 atgattcttt aactaaagag tatggaaaag aaattccagc cattggattt acactaagtg
     1201 ttgatgagtt aatgaagtat gtatataagt aaagtttaga aggagggatt gctttggatt
     1261 atttgactat agcactagca aaaggacgaa ttgaagggga atcatttaaa aaatttaaaa
     1321 aaatgggtct aggagatagt atagacacag atacgagaaa actaattttt aaagatgaag
     1381 aaaataaaat tatatatata catgtaaagc catcagatgt agttacatat gttgaaaaag
     1441 gagtcgctga ccttggtata gcaggtaaag atactatttt agagaatgag acagatgtat
     1501 atgaaatata tgatttaggt tttggaaaat gtaaatttgc tgtagcagga ttaaagggag
     1561 atagcatata tagagaagat gaatatctaa aagtggcaac aaagtatccc aatatagcaa
     1621 aaaagtattt taaagagaaa ggtcaaaaaa ttgaaataat aaaattaaat ggttctgtag
     1681 aactagctcc aatagtaggg ttgtcagatg taattgtaga tatagttgag actggcaata
     1741 cacttaaagc aaatggtctt gaaatattag aagacatatg taatataagt gctagaatta
     1801 tatcaaatag agctagctat agatttaaat atgaacaaat tcagaatata attcgtttat
     1861 ttgaagaact tgataattaa aatataattg aactttataa ggagggattt aagttgagag
     1921 aaaaagaaag tataagagag ttaaggggat atgaaccaaa tcacgtaaac tgtaaagtaa
     1981 aacttgatgc aaatgaagga agtaagaggt tgtttaaata ccttattaaa gaaatttcag
     2041 atagtgatat agatttaaat ttatatcctg aagattctta tagtgatttg aaagaatcta
     2101 taatagatta cataaatatt tctggagtaa ataagaaaaa tcttctagta ggaaacggtt
     2161 caagtgaaat aattgattta ataatacata cttttgtaga taaagatgaa gtaatattga
     2221 gtttctctcc aagttttagt atgtattcta tatatagtca gataaatggg tctaaattta
     2281 taggtgttga aagtgatgaa aatttagtta taaatataga taatgtgatt gaaaaagtaa
     2341 aggagaataa tcctaaaata gtaattgtat gtaatcctaa taatccaact ggaacaatat
     2401 taaagaggga agagataata aagcttttag attcaactaa tagtctagtg gttttagatg
     2461 aagcatatat ggattttgga gaagaaagca tgttaagtga tgtttttaag tatgataatc
     2521 taatagttct tagaacttta tcaaaggcat ttggattggc tggaataaga acaggatata
     2581 tgttatctaa tagtagttta ataaattctg ttgagaaagt aagacctcca tataatttaa
     2641 attcattatc agactttatt gctacaagag cacttagaaa taaagatgtg gtaaaggctt
     2701 atataaagga agtaaaagag gaaagagaag ttttatatga agaaatgatt ggtatgggaa
     2761 ttaaagcata caaatcacaa gcaaatttta tattatttta ttctgaaatc gaaaatttat
     2821 cacaaaaact tattgataga ggagttttaa taagaaaatt tggtggaaag ttagaaaatt
     2881 attacagagt tacaattggt gataaagaag aaaattctat gtttgttgga gctataagag
     2941 atattttgaa aaaggagaaa taggtatgag aatttggaag gtagaaagaa atacttttga
     3001 aacacagatt ttagtagaat taaatattga tggttctggt aaagctgaaa tagatactgg
     3061 aataggattt ttagaccata tgcttacctt aatgtcattt catggcaagt tcgatttaaa
     3121 agtgatttgt aagggtgata catatgtaga tgaccaccat agtgtagaag atataggtat
     3181 agctataggt gaagcattta aaaatgcact aggtgacaaa aaaggaatac gaagatattc
     3241 taatatctat atacctatgg atgaatctct atcaatggta gcaatagata taagtaatag
     3301 accttatctt gtatttaatg ctaaatttga tacccaaatg attggtagta tgagtactca
     3361 atgctttaaa gaatttttta gagcttttgt aaatgaatcg agagtaacat tacatatcaa
     3421 tctcttatat ggggaaaatg accatcataa gatagaaagt atttttaaag catttgcaag
     3481 agctttaaaa gagggtagtg aaatagtttc taatgagata gcatcttcaa agggggtttt
     3541 gtagaatgaa tataatagta gactatggtc ttggaaatat agattctgtg tctaggggtt
     3601 ttagaaaagc tggaatagaa actaaaattt ctagtgatat agatgaaata aaacaggcag
     3661 attcacttat acttccaggt gttggagctt ttagagattc tataagtgcc ttagataaac
     3721 taggattgat accaataata aaggagcatg tttctaaggg taaatttatg ataggtatat
     3781 gtctaggaat gcaattactt tatgaaaaaa gttatgagta tggagaatat gaaggattag
     3841 gacttataaa aggaagtatt gataaactgg atataacttt aaaagtgcca catatgggat
     3901 ggaataatct aaaatttaat aaggcaaatg atgatatact taaatatata aacgaagatg
     3961 attatgtata cttcgttcac tcatattatg caaattcatc aaatgaagaa ctagttgcat
     4021 tttcagaata tgaaaagaaa atccctgcta ttgttagaaa aggcaatgta tatggtatac
     4081 aatttcatcc tgaaaaaagt ggagaagtag ggttaaatat attaagagca tatggggaga
     4141 tgataaaatg ataatatttc cagcaataga tataaaagat aataagtgtg taagactcac
     4201 acaaggagaa tttgacaaag taaatgtata ttatgataat ccattagaag tagcatataa
     4261 atggaaaaat gaaggagcag aatatataca tatagtagat ttaaatggtg ctagaagtga
     4321 atttggtata aatacaaaaa taattgagga tatagcaaac aatatagata tacctattca
     4381 agttggtggt ggagttagag ataagggaaa agtcaaaagt ttaataaatg ctggtgttac
     4441 tagagtaata ttaggtagta tagcgattga aaatttgaat ttggttgaag aattggtcaa
     4501 tgaatataaa gagaaaattg tagtttctat agacgctaaa gatggaaaag tagcagttag
     4561 gggatgggaa gttgtaagcg atgtagactc attaacatta tgtaaacaac ttgaaaagat
     4621 aggtgtacaa actattgttt atacagatat atcaaaagat gggatgttgc aagggccaaa
     4681 ttttgacata tatgaaagaa tagcaaagga aacgtcatta aatgttattg cttctggagg
     4741 cgtaacttct atagaagacg taaaaagact aaaagctatg aacttatatg gtgcaataat
     4801 aggtaaagcg ctttatgata aaaagataga ctttaaggag gcacaacaat tatgcttact
     4861 aggagaataa taccttgtct agatgtgaga aatggaagag ttgtaaaggg aaaaaaattt
     4921 aaagatatag tagatgttga tagtccagaa gtacttggaa aattttatag tgattgtggt
     4981 gcagatgaac ttgtattcta tgatataact gcatcaaatg aagagagaaa gacatcttta
     5041 gaatttgtga caaaagttgc agaaaatata aatataccat tttgtgttgg tggaggagta
     5101 aataaattag aagatttcac tgatatttta agaaaaggtg ctgataaggt ttctataaat
     5161 tcatcagcag tcaaaaatcc tgaattaata agggaagctt cattaaaatt tggagcacaa
     5221 tgtgttgttt tatcgataga tgcaaagaaa aatgaagagg gttcatggag cgtatacgta
     5281 aaaggtggaa gagaaaaaac taatctggat gcaattgaat gggctgttaa aggtgtagaa
     5341 cttggagcag gagaaattgt tgtaaatagt atggacgaag atggaatgaa aaatggatat
     5401 gatatagaat tattatcaaa gataacttct ttagtaaatg tacctgtcat agcatctgga
     5461 ggcgctggaa aaaaggaaga tttttatgag gcagttaata aatctaatgt agatggaatt
     5521 ttagcagcat ctgtttttca ttttggcgag ataaaaataa acgatttaaa gaaatattta
     5581 aaaaacatgg gtgtagaagt aagattataa gttaaatact aaaaggagat tagaaatatg
     5641 gataataagt gtaacaatgt atacagtgat gaagtagagg aatttataag aagtataaag
     5701 tttgatgata aagggttagt ccctgttgtt gttcaagagg tagttagtaa agatgtactg
     5761 atgttagcat atatgaataa agatgctata aagaaaacct taaaagataa agtagcttgc
     5821 tattttagta gaagtagaca aaaactttgg gttaaaggtg agacatctgg taatactcaa
     5881 aaagtagtta agatgtctta tgattgtgat gtagatacta tactactttt tgttgaacaa
     5941 actggtgtag cttgtcatac aggcaattat tcttgttttt acagagactt gtttgatgat
     6001 agttcaaaaa tggagcctga agtacaaaca aatatattga aagaattata tgatttaatc
     6061 aatgaaagaa aaaataatcc agttgaaggt tcttatacta attatctttt tgaaaaagga
     6121 atagataaga ttcttaaaaa agtaggtgaa gagagtagtg aggtaattat agcatcaaaa
     6181 aataccgata aaagtgaact tatttacgaa attagcgatt tagtgtatca tacattggtt
     6241 ttaatgatag aaaaaggtgt tgaaattgat gaaataaaaa aagaattact taaaagaaga
     6301 aaatagaata ggatagatta atggtaataa gaaaatatac cgcttttaat aaaaagtggt
     6361 atatttttta ttttatattt tcgatttata gaataatatt taaattactt gataaaatta
     6421 actatatata taatttattg ataaaataat tgtagtacat tatttatttt
//
LOCUS       DAEQJM010000125         6308 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.128, whole genome shotgun sequence.
ACCESSION   DAEQJM010000125 DAEQJM010000000
VERSION     DAEQJM010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6308
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.128"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            230..1309
                     /locus_tag="KRQ43_003527"
     CDS             230..1309
                     /locus_tag="KRQ43_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH2743861.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDEINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYMKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRRH
                     YPGIHSITIIINGVEKGKLDFELGV"
     gene            1633..2001
                     /locus_tag="KRQ43_003528"
     CDS             1633..2001
                     /locus_tag="KRQ43_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH2743862.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2118..2921
                     /locus_tag="KRQ43_003529"
     CDS             2118..2921
                     /locus_tag="KRQ43_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2743863.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGATSEGRRSMMKMLEGYEKKELCHLMYLGFAGFMPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPSELNQIMDIFIKQLNI"
     gene            3306..4196
                     /locus_tag="KRQ43_003530"
     CDS             3306..4196
                     /locus_tag="KRQ43_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH2743864.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSARFDAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTIQNKDSCEKLLREECARYGILTD
                     MKEIIKAYKRSESYIQIKFF"
     gene            4659..5102
                     /locus_tag="KRQ43_003531"
     CDS             4659..5102
                     /locus_tag="KRQ43_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2743865.1"
                     /translation="MIEIKTIEINKKSQIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            5274..5444
                     /locus_tag="KRQ43_003532"
     CDS             5274..5444
                     /locus_tag="KRQ43_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743866.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            5995..>6308
                     /locus_tag="KRQ43_003533"
     CDS             5995..>6308
                     /locus_tag="KRQ43_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HBH2743867.1"
                     /translation="MTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFINDI
                     LKDAPYANRNIKPFTHIKRIIKAETDPTINYIGEKRPRLYILAEDEESNHINIEMQRA
                     LE"
BASE COUNT         2427 a          661 c         1135 g         2085 t
ORIGIN      
        1 agtaaagtat aaaattctat tactataata aaagatagaa ctagaagtct ttatgaaagt
       61 gggaaaagta tttatataaa taaatttata tggtttatag tttaacagta ggaaatatcg
      121 tatgagtgag aatatcgtat tttacataaa gatttagcaa tatgacacac tgttgtcgtg
      181 ttctgtagga tatgattaat aaatcagata tgaaaggaga gtgagtaata tgccagaatt
      241 actaaaaaat atgtataatc gtgagtcact ttatgaagtt gcagtagcta tccaatcagt
      301 ttacaactca tttaaggtag acgagttcat aaaatctaca atggatgaga catggaataa
      361 cttagaatta aaagccagat gtcgaaagat aagtatgagt ttaggaatgt atttaccaga
      421 agactataag gaagctcttt ccattcttga aaaatcagtt acaggttttt attttgcttt
      481 tttctttcca gattttgttg aagtttatgg gcaggacgaa ataaattggg atttatctat
      541 aagtgcatta gaaagaaata ctgagtattg gtcttcagaa tttgctgtaa gagcatttat
      601 catcaaggat gaagagcgta tgatggcaca gatgcgtaaa tggtctaagc ataagagcga
      661 acatgtacga agacttgcaa gtgaaggttg tcgtccccag ttgccttggg gacaagcaat
      721 atccaaattt aaaaaagacc ctacacctgt actgcctata ttggagcaac ttaaaacaga
      781 tacatcaacg tatgtacaaa agagtgttgc taataatcta aatgatatct caaaaacaca
      841 tccagattta gtcataagca ttgcaaagga ttggtacggt aaaaataaat ctactaactg
      901 gattgtaaag catggttgta gaactctact aaaaaaaggc aatcgtgatg tattagccct
      961 ttttggatat gatgatacta cttctataaa tcttcaggac tttactttag aaacaacgtc
     1021 tatttctatt ggagaggatt taactttttc atttaatatt ttagcaaaaa aagcgacaaa
     1081 aacaaggctc gagtacggaa ttgattatat gaaatctaat ggaaaaagga ataggaagat
     1141 atttaaaata tcggaggttt cattaaaaga aaatgagaaa aagtcatata tgaaaaaaca
     1201 ttcatttgca gatgtaagtg taaggagaca ttatccaggt atccactcga ttactattat
     1261 tattaatggg gtagaaaaag gcaaacttga ttttgaatta ggtgtataat tttactaaca
     1321 gcataaccta tatcagatac tttgctaaac ctatatcgta tactctaata aatctatatt
     1381 aggtagttta ctacttgttt actgaattta aatacaaaga aatacaggtg ttaatccctg
     1441 cccattaaag gaatatgagc ataacacaaa agtagaactt atcaattctg ttacgggtat
     1501 agtagtaaat ccatagaatc acaattagaa gatgaagtgt aaaaaataag ttagtgttga
     1561 ttttagttgc tagtgatatt gaatagttat acaatagcca tataaattag aatttgtaga
     1621 ggagaaatgt aaatggatgt atatagtttt tggaatgaca ctttggcaca agatgctgtt
     1681 aagataagaa aatattttca tgaagatgct tatattaatt ggcatgatac aaatgagcat
     1741 tttactttag aagaatttat tattgcaaat tgtgagtatc ctgataaatg gaatggtaaa
     1801 gtagaaaggg tgctagaatt tggaaattta gtaattacag tgacacatgt ttatgcaata
     1861 aataaaccac tatcatttca tgtcgtttca tttatcagcc ttaaagatga taagattatt
     1921 tctattgatg aatattgggg agaggatgat gatgtgccac agtggagatt agataaacat
     1981 attggaaagc caataaaata gtgtttgttc tgttttataa ctgaaatttt gataacattt
     2041 gatattttga tttgtcattg gtcaacatag tcgttagtgt aataatttaa aaaagtagaa
     2101 tttggagagt gagcactatg gaagaaaaat acatcttatc tgaccgaggt aaagtatatt
     2161 attggataaa agaaagtaat agtgtgtttg caaagaactt aatttttttg ccaggactaa
     2221 cagcaaatca tcatcttttt gatttccaga tacagtactt ttcaaaaaat cataatgtat
     2281 tggtatggga cgctcctgct catggaaaat caagacctta cttagatttc tcatattcta
     2341 acttggtaga agaattgaaa gtaattttag ataaacaaaa tatgaaaaag gttgtactta
     2401 tagggcaatc ggcaggggga tttgtggcac agtcctttat tgtaaaatat ccaaatatgg
     2461 tagaaggatt aatgatgatt ggaacttgtc catatggaac tgactattat agtaagtcag
     2521 atattttctg gttaaaacag actgaatgga tgttaaagtt attcccagat aaattgttgc
     2581 gaaacataat atctaagatg tgtggagcta cgtctgaagg cagaaggagt atgatgaaaa
     2641 tgttagaagg ctacgaaaaa aaagaactgt gtcatctcat gtatctggga tttgctgggt
     2701 tcatgccaga aattcaagac ttaaatatac attgtccagt ttgtttggtg gttggagata
     2761 aagacaagac gggtaaagtg agaaaatata atgagcagtg gcacaataag actgggtatc
     2821 cattgcacat tataaaaaat gcttcacata atgtaaatgt cgataaacct agtgaactaa
     2881 atcagattat ggatatattt attaagcaat taaatatata aaaactacat actcattagg
     2941 taaattatgt agtatatgtg tttacatatg gttatagaaa taaatatgta ataaactact
     3001 taacacttaa aaagtggatt tgtccagagc ataatacaaa gcatgatata taaattttta
     3061 agcgaaatac atcaaaagaa gtattagaat tagtggagat aaaacagcta ttagagatta
     3121 taaataaata gttttaaagg tactacgaat atagaggaag gtaaatcata cgttattcaa
     3181 ggattataaa tgagtagttt aaaagtacta tcggataggt ctctgcatat ttaaacctta
     3241 gtaaaggtag ttaaagtagt agtttaaaaa ctaaaaaatt atataaagga attaggtata
     3301 agaaaatgat tgagagtata ccagcaaaac aaattttaca aaaagtgaaa tttgacaata
     3361 caagatggtt tggaattgac tataatatga atctctatcg tggttgttct catggatgta
     3421 tatattgtga tagccgtagc acaatataca acatagagaa ttttgacaaa gttagatata
     3481 aagaaaatgt gatagagatt ttaagtaaag aattgcgttc aaaaagaaaa aaaggggtag
     3541 taggcattgg agctatgtct gacacatata atccttttga aaagcaactt tgtattacaa
     3601 agcaagcact agatttgatt tcggaaaatc attttggagt gtctattgat actaaaagta
     3661 gtttggtggt tagagatata ccgattttgc agaaaattaa aaaaaataat tctgctattg
     3721 taaagttgac tataaccact gcaaatgatg aattatcaaa gaaaatagaa ccttatgtaa
     3781 atccaagttc tgcacgattt gacgcagtga aagaacttaa tgattctgga attttttgtg
     3841 gcatattatt gactcctatg cttccatttt tgactgataa taaagatgaa atacgagcaa
     3901 ttgtagaaaa agcacacaag gctaatgcaa agtttattta ttgcatgtat ggtgtaacaa
     3961 tgcgtagtgg tcagagagag tttttttatg agcatttaag agatatatca ccaaaattag
     4021 tacttaaata tcagaaaaca tatggtttaa actatgtatg tactatacaa aataaagatt
     4081 cttgtgagaa gttgttaaga gaagaatgtg cacgttatgg tattttgaca gatatgaaag
     4141 agattataaa agcgtacaag aggtcggagt catatattca aataaaattt ttttaagata
     4201 ggctttggat gagatataat agtggtgatt gatgtgttga tattatagtt gattgttaga
     4261 gaggatatta tagatgaata ttaatattga tattctaggt aattgctaga actaatatta
     4321 tagatgaata ttagtattga tattctaggt aattgctaga gttagtatta tagatgaata
     4381 ttagtattga tattctaggt aactgctaga gctaatatta tagatgaata ttagtattga
     4441 tattctaggt aattgctaga gctgatatta tagatgaata ttagtattga tattctaggt
     4501 aattgctaga gctgatatta taatttatta ttaatattaa tattctaggg aattatcact
     4561 atattttaaa aagtaaaaat atatatcaaa atgaactaaa taagtactgt aagaagtttg
     4621 ttaaattaag gtttgaataa agtgagggtg gagaacttat gatagaaata aaaactatag
     4681 aaataaataa aaaaagtcaa attgaccttt taatgttagc cgacccatgt gaagaaatga
     4741 ttgataaata tctcaataaa ggaactatgt acgcattgta tgataataaa gaacttactt
     4801 gtatagcagt tgtaaatgaa atttccaaag aaatatgtga attaaaaaac attgctacat
     4861 atgagcattt tcaaaatatg ggttatgcct caaagatgat ttatcatctt ttagatgttt
     4921 atagtaaaaa atattcatca atggttgttg gtacatctga aagcggagtt cctttttatg
     4981 agaagtttgg atttgtttat tcacataaaa ttaaaaactt ttttgtagat aattatccag
     5041 aaccaatctt tgaaggagaa ttacaatgtg ttgacatgtt gtatctatca tataactttt
     5101 agataggata atatttttag gtagatataa ttaattaatt catataatta tcggaattat
     5161 aatttataaa ttatgtataa taagagtata atttatttag aagctgttat attgtattat
     5221 attcaaataa gatatataat aatttgttta ttttgaattt tggaggatta attatggatt
     5281 caaataataa tactataaaa tcaactgtta aaaagggtat ttcttttggt tcttgtttag
     5341 caatgattat ttcttatact gcatggaaat ctattccatg ggctattttt catggcttaa
     5401 tgagttggat atatgtactt tattattggg ttaagtatgc atagattaaa ttaataaata
     5461 agtatgtaat attgtaaagt ttaagaaaca aaatgtaagg gagtgtctcg aagtgaactt
     5521 tttagtttat aaggcactct tttttgtatt aaataaaata tattttcatt acttaaacaa
     5581 tgaaaaagat gagtatctct attttaatac atacccttat attcattcat ttatcaacaa
     5641 tagttttaaa aagaaagcta tctaaaatct attgtaatct aagtgcttct ctttaaagtc
     5701 ttaactttag taatgatata taagtttata aggttcttat ttcaataatg caaattttac
     5761 ttagaagttc agactttggt atgaagaaat gggtaataat aaaaaagagg tgttgatatg
     5821 aaagaaaaat tagaagaaaa atctaagatt attaaaacat caaaagagta taaacgaact
     5881 ataattgaag aaaaggacag agaatgaacc aaaaaattaa atgacatact tagtagaggt
     5941 gatttttcta atgaaaaatt agataaaatc aaggatttaa ttccaaaaga aatattgact
     6001 agtgaaaatg ttggagaagt tgtaactgaa gatgggtatg ctaagcctga gtatgatgag
     6061 gtatttaaat cattgtttac tttaaataat gattacgatt tacttgcaaa ttttataaat
     6121 gatatcctca aagatgctcc atatgccaat aggaatatca aaccgttcac tcatataaaa
     6181 agaataatta aggctgaaac cgacccaaca attaattaca ttggtgagaa aagacctaga
     6241 ctttatattt tggctgaaga tgaagaaagt aatcatataa atattgagat gcaaagagct
     6301 cttgaaga
//
LOCUS       DAEQJM010000126         6026 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.129, whole genome shotgun sequence.
ACCESSION   DAEQJM010000126 DAEQJM010000000
VERSION     DAEQJM010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6026
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.129"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(214..723)
                     /locus_tag="KRQ43_003534"
     CDS             complement(214..723)
                     /locus_tag="KRQ43_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBH2743868.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(725..1372)
                     /locus_tag="KRQ43_003535"
     CDS             complement(725..1372)
                     /locus_tag="KRQ43_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743869.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(1386..2558)
                     /locus_tag="KRQ43_003536"
     CDS             complement(1386..2558)
                     /locus_tag="KRQ43_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH2743870.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAE
                     RLKLEFEKEGLDCELVDVGENGNTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGALCAFNMETGLVDNSLCIGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSRENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            2826..4202
                     /locus_tag="KRQ43_003537"
     CDS             2826..4202
                     /locus_tag="KRQ43_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743871.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEILNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(4453..5286)
                     /locus_tag="KRQ43_003538"
     CDS             complement(4453..5286)
                     /locus_tag="KRQ43_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH2743872.1"
                     /translation="MTIKEVEEKTGLTRSNIRFYENENLIKPLRNERNGYREYSDENV
                     EDIKKIAYLRTLGITIDDIRNIILQKVSLVEVVEKQEKVLETKISDLENAKTMCNKML
                     ESDELSYLNLKVEQYITELPEYWNKNKPVFKLDSVSFLYIWGGKITWGIITIACLLIA
                     ITVFPKLPPQIPIQWNNGVANYVDKKFIYAYPVICVVFRILLRPFIWRWLQIHAFYSD
                     TIADYLTNFMCFVALSIEIFSILFIYNIARHVTIIIFIDILVFIVLLIIGVYKLFKKY
                     N"
     gene            complement(5615..>6026)
                     /locus_tag="KRQ43_003539"
     CDS             complement(5615..>6026)
                     /locus_tag="KRQ43_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH2743873.1"
                     /translation="GIDYENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMG
                     ASKKGSYGASIIEKIESIIPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQ
                     QLNNHEESQSHPDEQEIYEASMFAKNMMIKASIV"
BASE COUNT         2102 a         1028 c          646 g         2250 t
ORIGIN      
        1 tttcattgtt gaaattatga aaatatactt gatttaatac caaaagagta tctcatgaac
       61 taaaaagttc attttgagat actctcttct tttttaatta atatacatat taattactat
      121 attagtttat tactatatat caattactat tcattaatta ctattcatca attcttatat
      181 atcatttata attaggttat aattttatgt tatttacatt aatcccataa cagtgagtaa
      241 aactcttact atcaacatcc ccactattgc atcaaatata ggaactgcca acagtaacat
      301 tctatactta gtactggcat ttgctacaag cactattctg gcataatgac caactagagt
      361 acccattaac atacatggca taattaatat ggttgcttgt ggtgcagtga ttagaccttg
      421 tgcaaataag tttgcagctg tagctgctcc tgctgcctta gcaaagaatg ctgctatcaa
      481 aactacaaca gattccccag gtagtccaaa aatacccatt actggaccaa aaatatttcc
      541 taaaatatca actaaaccag ttaattgtaa aaactgcact attacataac ccattatcat
      601 ggctggtaat atctgttcaa cacctatgta aaaacctttt tttgctcccc ccataaatat
      661 ctcaacagca gttttcttag gtttactatt tacaattgca tttccagtat tttgttgact
      721 catactacac agcctcctta gccttattct ttttatttct tacacctatg attaatctaa
      781 ctagattagc accaagtatt ttacagaata tctctataag gattattgga cctaatgcca
      841 ataatgctat tggtaaaagt ggagcttgag tatttattgt gttcagtata acagctgaac
      901 cagcatattg atatgctaca aatatagttc tttcatcatc tgttatttcc ccactttcaa
      961 ataattcttt cgtcattatt gaggctacat ctgaactagt aaatgaagat acaaatgcta
     1021 ttcctgctat tccaggtata ccaagcagag gtctaagtaa tggattaaat atctttgatg
     1081 ctgctttcat tcctcccata gattcaacta catctataag acctacagca aaacagacag
     1141 ttggaatcaa agtcagagca aataagaaac catcttttgc tcccgttcct cctttaccca
     1201 taaagtctac accatctgca atagtaccaa atgaacctgt cagattagca aaatctaatg
     1261 ctttaaggaa gccttgacta tctttaaata ctcctgaaaa taatactatc aatacaaata
     1321 aagataaata ccctttccat gttaccttat tatctccagc tgttacatcc atataaaatc
     1381 cccctttata cctcaaattt atctaagttt aaaataactg tagaaattaa tttcaccctc
     1441 tcaaacatag aatctactac tgcatattct cttgatgtgt ggttccattc tcctcttaca
     1501 ccaaatgaac agattgtagg aacgtttgca atagttaaat aacttgcatc tgaactacct
     1561 ccaagtctct tagcatttaa ttctccaaat ccattttctc ttgacacttc atttacaaat
     1621 gtatgaaatc tcataacatc ttctgtagtt tcaaatggca tcatttcact tataaaatta
     1681 acttctgtag aagttccttc tatgtaagtt tctttacata tctctctaac ttgttcttta
     1741 acattctcca tttcttctac tttttcaaat ctaaggtcta cttttatact acaatcttct
     1801 ggaatagaat tttccactct tccaccctta atcacactta cacttactgt agttccaaca
     1861 tctaaattag tcaatttttg tatgcgtagt atcttattag ccatttcttc tatagcattt
     1921 cttccacctt caaaatcatt acctgcatgt gtttctacac cttttacatg tatattacat
     1981 cctattcttc cttttctacc tatacataaa ctattatcta ctaatccagt ttccatatta
     2041 aaagcacaaa gagcaccttt tgcttccctc aatataacat ctgcaccagt tgaatcttta
     2101 tgacctatct cttcatctcc agaaaatact atttttattg gtctttcttt gtatcctatt
     2161 ttatttaaag ctttaataac gtataaagag attattatac cccccttcat atctaaaaca
     2221 cctgggccat atgcttttcc ttctattatt ttaaatggat tctctccaaa tgtacctgtt
     2281 tcaaagacag tatccatgtg tcctgaaaaa attatcggct ttttatctat attagaacca
     2341 agtgtaccta tcaatgtatt accattttcc ccaacatcta ctagttcaca atccaaacct
     2401 tctttttcaa attcaagctt taatctctca gctaacttgt ttacactttc tttacaatgt
     2461 gtataacttt ctatattaac aatctctttc cataatgaaa ctatttcttc tctattctca
     2521 tcaacaaact tagaaatttc atttaaatat gtattcataa tcttctcctt tattttcaaa
     2581 taaaatgtat ttctttccta aaatctaagt ttattttagg aaatcttaaa agactagtcc
     2641 ttaattacaa aatagcacaa ttattcttgc cagtcaacat atttttcagt cttttttata
     2701 ttttctgatt tttctttcaa ttatcctttt gtaaaataaa ttgacgcgtt ttatctacta
     2761 ttataaaatg aggttataaa ttgattgatt agttacaata ctctcgaaat tttaaaggag
     2821 gttttatgaa atataaaatt ggttttttga caacatctta ttttatgtca gataagttta
     2881 aacaagctct taaagaatta aatgatactt gtgaaattac atttattgag cttaaagggg
     2941 agaatccttt taataattta cctaatatat actatgagca agtagataat tttgatggat
     3001 ttgtatgcag tggtatagtt ccatatagtg aacttataat aaatataaaa gacataaaag
     3061 ttccattaaa ttttttaaag cttgatgaaa gagattttta taaatactta ttcaaattat
     3121 taaatagcca aaaagatatt gactttacaa aatcatttat ggatttttta agagaggaca
     3181 acaattatta tgatatatat tcattaatag actctaataa atgtccatat acaattaaag
     3241 attttaatat ccctcaacct gtatatgact ttaaaaaatt aaatgataaa ttattggaaa
     3301 tacatttaga cttattgcga gataataaga ttaacctttc ttttactaga aattacatca
     3361 ttagttgtga acttaataag cttggatatg attgtattta catggttcca tctacagaat
     3421 caatcctgaa tacatttaaa tctctggtga atgaaataac attacaaaac ttagacaaaa
     3481 ataaatctgc aacttgtata gttacagtaa atagttcaga gtacataaat gaagatttga
     3541 tatttaaaaa tgatgagata caaaatcaaa tatataacac tatattaaat tctctatcaa
     3601 gacatggatt ctatggagtt caggtcaaaa aaaatgatat gaaaatagag atacacacta
     3661 ctaaagaaat attaaacaat atgaccaata actatacaga tttttttatt tcagaagatt
     3721 taaaagaaat taaatatagc ttaaatatag gttggggcat tggaaataca aatattcatg
     3781 cagagcaaaa tgctcgtcag gctaatggta aatctgcttc tttgaatgga aactgtactt
     3841 ttatagtaaa tgatactaat gatacaatag gccctttata ttcaaataaa aattctaata
     3901 atattgaaga tagctcaata gccaataaag ttgcttcttt tatacctcta tctaatacaa
     3961 atgtatctaa aatcatgtgt atgattaatg atagaaattc aaataatgtg tcagcagaaa
     4021 tattagcaga ctatatgaac ataactctta gaagtgctaa tagaatattg agtatcttat
     4081 ataaagcagg aattgcaact attgtaaata caaaactcga taatcaaaga ggaaggccaa
     4141 aaaaaatata taaagttgat ttcttatctt ttctaaataa gatgcagaaa ttaaattctt
     4201 aatatttaat tttttaataa aagcaatgta ttttctctaa ttttaaagaa tcaaaatgtt
     4261 taaattttat tagaatatac aactttttac tttaaaatac ctaaaccttt tatcagtgaa
     4321 ataaaccata atatatcgta gcttattaga aaaacaaaat aatttcatat acaaataata
     4381 aaatagccac tacaatccat aatttgcagt ggctactttt tacactatca cttattactt
     4441 aatttttaaa aattaattgt attttttaaa taatttatac acacctatta tcagtaaaac
     4501 aataaataca agtatatcta taaaaataat tattgtaaca tgtctggcaa tattgtaaat
     4561 aaaaagtata gagaatattt ctatagacaa cgctacaaaa cacataaaat tcgttaaata
     4621 atctgcaata gtatcactat aaaaagcatg tatttgtaac catctccata taaatggacg
     4681 taaaaggatt ctgaatacaa cacaaatgac agggtaggca taaataaatt ttttatctac
     4741 ataattagct acaccattat tccattggat aggaatttga ggtggcaact ttggaaatac
     4801 tgttattgca atcaacaaac aagcaatagt aataattccc caggtaattt tccctcccca
     4861 tatatataag aaacttacag agtcaagttt aaaaacaggt ttgtttttat tccagtattc
     4921 tggcaactca gttatgtatt gctctacttt caaattcaaa taacttagct catcagattc
     4981 taacatttta ttacacatag tttttgcatt ttctaagtct gatattttag tttcgagaac
     5041 tttctcctgt ttctctacaa cttcaactaa agatactttc tgtaatataa tattacggat
     5101 atcatcaata gtaattccta gtgtacgtaa atatgcaatt tttttgatgt cctctacatt
     5161 ttcatctgaa tattctctat agccattacg ctcattacga aggggtttaa ttaaattctc
     5221 gttctcataa aaacgaatat tagagcgtgt caatcctgtt ttttcttcaa cttctttaat
     5281 tgtcatttta aacactacct ctctattcta ttaatttaca actataatat agtcttaaat
     5341 attttcactc tataaaattg tatatttagt atatcttaaa atcaagttaa ttatctttta
     5401 taaattttca tacaataata tctcctttca ataatatctc tttttctata tttaaaacta
     5461 tcttattttc tataaaataa tgtataaaca aggtttacag tcaagtattt ttattatttt
     5521 tttgatttca taaaaaaaag catagcaaat catttgctat acttttttac taaattattt
     5581 attctatatc ttatatgaac ttattgttta actactacac aatactagct ttaatcatca
     5641 tattttttgc aaacatactg gcttcatata tttcttgttc atctggatga ctttgagatt
     5701 cctcatggtt atttaattgt tggcgaatat gttcgttgtc aggagaaagt tttaacatct
     5761 ctttatattt tgctttcaat ccttctgcta tcttaccttg acatatgaat gaacctaata
     5821 tttcattatc ttttgggata attgattcta tcttttctat tatactagct ccataacttc
     5881 cttttttact tgctcccatt gttccaaata gtgctatctt tttattgtga atattttcaa
     5941 gcacttgttt tgaattttta tcacaaattc ccttgtccac ccaatagcct aagaatacta
     6001 tatcataatt ttcatagtca atacca
//
LOCUS       DAEQJM010000127         5609 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.130, whole genome shotgun sequence.
ACCESSION   DAEQJM010000127 DAEQJM010000000
VERSION     DAEQJM010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5609
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.130"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            257..1021
                     /locus_tag="KRQ43_003540"
     CDS             257..1021
                     /locus_tag="KRQ43_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH2743874.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            complement(1302..2417)
                     /locus_tag="KRQ43_003541"
     CDS             complement(1302..2417)
                     /locus_tag="KRQ43_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH2743875.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(2458..3984)
                     /gene="glpK"
                     /locus_tag="KRQ43_003542"
     CDS             complement(2458..3984)
                     /gene="glpK"
                     /locus_tag="KRQ43_003542"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH2743876.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFESGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKEIKMLRVDGGITKNNFTMQFQSDILDIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTKQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            4277..5374
                     /locus_tag="KRQ43_003543"
     CDS             4277..5374
                     /locus_tag="KRQ43_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH2743877.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILFTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
BASE COUNT         1886 a          958 c          706 g         2059 t
ORIGIN      
        1 atctctatac tagtaaatta tataataaaa tcatatttta gtcaattgtt ttataaaatt
       61 tgagttattt tgaattatta aacatctatt tttacttttt tgcttaaatg taagttttaa
      121 atatggtaaa attatcttgc ataacactta taatattatt tgataaatat acatacatta
      181 acaaatatac ctaaactctg acttaattgt aagttatgcc aaaactaaaa taatactagt
      241 ccaaggagga tattttatgt taccacagga aagatacgag aagattttaa gtattctcaa
      301 atcagataat ataattaaaa taaatgacat agttcaaatg tttgatatat caatagaaac
      361 tgcacgaaga gatttagccc atatggaaag tatcggtctt ttaaaaagag tttatggtgg
      421 tgctatacca gttatagcaa gtagcgtaga acttaactat gttaaaagaa aaaaaataaa
      481 ctcaaacgat aaaaaacaga ttgctattaa atgtagtgag tttataaata caaatgatac
      541 tatttttatg gatactggaa ctactgtact tgaagtttca aaaaatttga aagataaaaa
      601 gaatctaact gtaataacca actcaatttt agttgcaaat gaacttatga atactaatat
      661 aaaagtatat gtgcttggtg gctatcttag agaaactgaa ggttcttttt ctggtccact
      721 tacactctca gctattgaac aatttaatgt tgataaagct attttaggtg ctggaggtat
      781 cactcttgaa aatggaatct ctgactatca cttagaagaa gcactggtta gaaaaaaaat
      841 gattgaaagg tctagaaaat ctatagtagt tgtcgaacct cctaagtttg gtataaattc
      901 atttgcatca gtagctccta tagaacacat agatactatt attacctctg ctagtataga
      961 ccataatata ataatagagt tttctcaaaa aggaatacct ttagtcatag ctgataatta
     1021 gcttgtatga ttgattttta gttccttgat gtaataaatt aaaattaagg agccaaataa
     1081 ttatttattt agctccactt atgtctaaac tatactttat attttaatta tgtaactact
     1141 ttcagttagc ttatcatttt tagttatttg attgccattt tatttaattt atcagttttg
     1201 gttattcgat tattttttaa ttgtctgtct ttttaattta tttttagtta tttaaactcc
     1261 tactttaaaa taacttaaat ttgacttaag tattgtttat tctacactgc atctttcttc
     1321 attttaatac tttgttcttc ttccaaagtt aaatcttttg tcataagtat agcaagtgca
     1381 attgccaata ctcctccaac caattttcca attacaacag gtgtaatcat ctctggaact
     1441 actcctgctg taaatcctaa atggtccccc aaagctgctg tagcacaaac cagccaagca
     1501 gtatttacta ctttcccctt tggactcata tctttcatca ttttatatac tggaatacta
     1561 ttggctaaag taaaaactaa tcctgctgca ctagtggcat ccatacctaa ttttccaccc
     1621 actattgtaa gtggtttatt aagaacttta actaataaat gtaatattgg aaaagtacct
     1681 aataacacta ttgcaatact tccaattact tgaatacctt ctcttatagg tgtcatgcct
     1741 tttataagta ctatacctgt tatttcttga aatgctgctg ctcccaaacc tatcgttatc
     1801 aatatagata taaattttcc aaaaactaat gacccattta tcataagtgt agaattaaat
     1861 tttaaaccta ctgccaatat tactgccaat attatcactg gtatcatatt tataattacc
     1921 attgataagt taaatcctgc tattaatcct cctataatac ctccaaaagg tattgttatc
     1981 aagcctatca gtaacccttt tgcaaagaat ggtctgtctt catattctat aagacctagt
     2041 cctactggaa ttgaaaatac taatgtacat ccaagcatgg atgacacgac taatcctgca
     2101 agcattcctg cctctttatt gtgtgcaagt tccatagcca atggataccc tcccatatca
     2161 ttcgctaaaa tagttgcaaa catagatggg tcagctccac agagattgaa tattggtatt
     2221 attataggac ctagtacatc tgaaattact ggagctaaac aaactatacc aaccattcct
     2281 aaagccaatg gacccattga attaaaccct tcttcaaact gctctccaag tccaaattta
     2341 tttccaatta ttctatctaa cgctcctaaa agcactccca cagccattat gtataatata
     2401 attttatcaa agggcatttt taattcctcc tatacatgta aaatactcta ttgtaactta
     2461 attagcacac acctttttgg tatcgttttc ccaattcata gctcttttta ctgcttgatt
     2521 ccatccaagt aatatttctt ctcttttttg cttagtcata tttggaatat attttttgct
     2581 tattgtaaat tcacttctaa tttcatcaat actgttccaa acaccacagg aaagccctgc
     2641 catataccct acaccaagta ctgtcgtttc aggattttct gcaatttcaa ttggtatatc
     2701 taatatgtca gattgaaatt gcattgtaaa gttattttta gtaattccac catctactct
     2761 caacattttt atttctttcc ctgaagccaa attcatggaa tcaacaacat ccttgacttg
     2821 aagtgcaaca gactcaagag tagcccttac tatatgttct tttttagtac ttcctgttat
     2881 cccaaccatt gtgcctctag catattggtc ccaataaggt gctgctatac ctgcaaatgc
     2941 tggtacaaaa tatacccctc cagtacttga tatggaattt gccatgtcat cagtttctga
     3001 ataatttttt ataactccaa ttccatctct aagccattgt attgcagcac ctgctatata
     3061 cactccacca tcataagcat atgtaacttt atctcctatc ttccaagcaa ctgttgtcaa
     3121 aataccatta cctgctatat ttaactcctc acctatattc atatataaga aacatcctgt
     3181 accataagta tttttaacca ttcctggttc aaaacatcca ttgccaaata aagctgctgg
     3241 ttggtctacc attgaagcag taatttttat agaaacccca caaaatgcct ccttatctgt
     3301 agttccaaaa tcaccactag taggcattat atctgctaaa atacttctag gcactcctat
     3361 aatgtcaagc aactctctat cccaatccat atctcttata ttaaaaagca ttgttcttgc
     3421 tgctgtagat acatcagtta aaaaagattt tcctcctgtc attttccata ttaaccaact
     3481 atccaatgtt cctgcaagta cttctccatt tttaattttt tcttttacac cttttacatt
     3541 atctattacc catttaattt ttgtacctga gaaatatggg tctataatta acccagtctt
     3601 atctattatc ttattttcta aacctggtat attctttaaa ttttccacat aatcataagt
     3661 tctcctacac tgccatacga tagcattgta aagtggttta cctgtatttt tatcccataa
     3721 cattactgtt tcaccttgat tatctatacc aattcctttt atatcacttt cattgattcc
     3781 actttcaaaa gcctgttgta atacattatt actcacagtt tttgtattat tccaaatttc
     3841 tatagggtca tgttcaacat atccagattg tggatatatt tgagtatgtt ccatataatc
     3901 gctaaaaaca aactctgatt tttcgtttat caatactgct cttgttcctg ttgttccttg
     3961 gtcaattgct aatacatatt tcacttaaaa tgtccccctt tattttcaga attaataaat
     4021 tcttttttat tttttgaata tataatctat tcaagttatt tatattttat atcatcatgt
     4081 ggatttatgc aatattcatt acaatatttt ttgttatttt taattatggt gattaaaaaa
     4141 gtatttttat tgaaatatta ttgcaatatt cattatttta ttctataatc tagttaaaat
     4201 aacacacaat attttaatat ttacacatag tcagtcattc gaaaatttaa atttaacttt
     4261 ttaaggaggc tttacaatga aaaaaacata tctattcagt cctggaccag taatggttac
     4321 agataaagtc agaaattcac ttcttcacta tgatatatgc catagaggaa acgagtttat
     4381 ggatttattc aaagatacac aacaaaaaat caataaacta tataatgcaa cttctaatta
     4441 ctactcatta attgtatctg gctctggaac atctgtaaat gaatgtgtac tatcttctat
     4501 ctttgacaaa gaagatgcag ttctgctagt tagtaatggt gtttttggag aaaggctaga
     4561 agaaatatta tttacttata atgtaaaaac atataagcct aattttgaat gggcagaata
     4621 cccagacctg gacattttag aaaaatatat aattgaaaat tctgatataa aagtaattgc
     4681 tatggtgttc catgaaacta gttcaggaat gataaatcca gtccctgaac taggaaaact
     4741 tgctaagaag tataacaaaa tattttttgt agatgcaata agtgcctcag caggtgaata
     4801 tattgatgta gaagagttta atatagatat aataacaggt gttggtggta aagctcttgg
     4861 agcatttcca ggttctgcat acctttgtgc taaagagagt attttacaaa atattaaaga
     4921 aaatcaatgt aagaatgtat atcttaatct ttataaacac tataaagttg ctaaatcatc
     4981 ttctcaaaca ccaaatacac ctaatgttac tttaatattt gcccttaatg aagctttaac
     5041 tgagtttttg gaagatgaca gtaaaataga aagatacaaa gaatgttctg ctattttaag
     5101 gaatggcatg gaagaattgg ggctaacatt tttacttcca gataagtata tgtctaatac
     5161 agtaacatct gtatttctac ctaaagaaat caatgtaaat gagtttatat taggcctaga
     5221 aagggaaagt ggctatgttg tctatccagg aaaaggcaaa ttcctagatg ctaacatatt
     5281 ccaagttgca aatatgggag aaatatatcc agaagattgt tataaattct tagatatctt
     5341 aaaatcaaaa ttggagataa aaaaagttat ataacagttt gtttgtaaaa tcctacaata
     5401 catcagtata aattaaatag actgattttt ttaaattttc ctataataaa ttatatttta
     5461 tatttttgta taagggtgaa ctataatatg taaagttcac ccctatttca aatctttttc
     5521 cttcagtata atctttttct tttaatttat tttatatttt tgacataatt attcttacat
     5581 ttaattgttt tttatttttg acgcaatcg
//
LOCUS       DAEQJM010000128         5555 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.131, whole genome shotgun sequence.
ACCESSION   DAEQJM010000128 DAEQJM010000000
VERSION     DAEQJM010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5555
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.131"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            506..910
                     /locus_tag="KRQ43_003544"
     CDS             506..910
                     /locus_tag="KRQ43_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBH2743878.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     FLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(1167..2162)
                     /locus_tag="KRQ43_003545"
     CDS             complement(1167..2162)
                     /locus_tag="KRQ43_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH2743879.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRNKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(2414..3250)
                     /locus_tag="KRQ43_003546"
     CDS             complement(2414..3250)
                     /locus_tag="KRQ43_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBH2743880.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHIGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(3738..4301)
                     /locus_tag="KRQ43_003547"
     CDS             complement(3738..4301)
                     /locus_tag="KRQ43_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743881.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(4399..5328)
                     /gene="glsA"
                     /locus_tag="KRQ43_003548"
     CDS             complement(4399..5328)
                     /gene="glsA"
                     /locus_tag="KRQ43_003548"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBH2743882.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
BASE COUNT         1835 a         1012 c          544 g         2164 t
ORIGIN      
        1 catttagata cttagctttt ttcatttact tatttaactt ttttacctac ttaactcttt
       61 tagatactta gcctttttaa tctattcaac cttttttacc cacttaacct tcttaccttt
      121 taatataaac tctaaaactt caaatatcat tagttatatt ttgacattct tcctatagtt
      181 aatgcaaaaa gattgatttt ttcttataat taatatccca tttacattgc catttattaa
      241 gtctttactt ggcttatatg gatttctttt tactctcttt actaaaccta tacttattaa
      301 tattatgaag gtcttataat agtctaatat gaatatgtcc atcatatatc aaattttaaa
      361 atttgtaagc aaaatactta tcttatatta ctacatctaa agtggaaaat tttacaaaca
      421 agccctgtaa aaacacttta aataacaatt tgcttttaaa tcatatacag attataataa
      481 atactgtata aggatggtga aaaatttgat taaaataaca attccaggta gacctattag
      541 taaatctaat tttaagcttc ataacataaa tggtcaagca tggatgcctt caaagggaaa
      601 atattctaag tatcttgcat acgaaaacat gattgcaggt tttataaacc aacagtatca
      661 aggggaaact gttgaagaaa atctaataac agtcttgaaa ttattctttc caaataagag
      721 aatgggggat ttacataatt atccaaaaag tatttgtgat ggtattgaaa aaagtggaat
      781 aataaaaaat gataaacaac ttaagccagt atttttattt gattttatag ataaagataa
      841 ccctagggtt gaaattgaac tttatccagt atctaaatac gatatatcct ataatatttt
      901 tgaaaaataa agattttatg tgttattcga cattatattg atactccagt atttgaaact
      961 atactaatac aacaataata attgtgttat gtctatactc aaacaaatgt ttttaaaaag
     1021 cattaagcaa atatttaata agtattaaac aaatattaaa tttatataat agctataact
     1081 atgtaaattt aatatttgta tataagacca catctaataa aaagaaatcg gagtaaattt
     1141 aatacaccga tttcaataaa taaaatctat cctagctttt caacaacagt cttaagcatt
     1201 tctcttatag gaagttcata tggacatcta ctctcgcaaa gcccacagtc aatacactca
     1261 gtaggtttaa catccataac ctcatatttt tctttagccc actcttttaa tccatatcta
     1321 gtataataac cttcacataa aaaactcaat ggtatattta ttcctacagc acaaggcata
     1381 caatattcac atcttctaca gaatttttta cctaaagaat ttcttatttc ttcaatttcc
     1441 ttattatctt tttcatctag aacaagattt tcaagtacag cgacattttg tctaacctgt
     1501 tcaacactct ccatacctgg tataactaca tctatgtaat ctttagatag tatatattta
     1561 atagccagtg ttgcattgtc taaagcacct ccagctaaag gtttcattac tattatccca
     1621 attccttttt catgagcttt tttaaacact tcatctgctt gtccttcaac tatattgtaa
     1681 gggaattgta tagtgtcaaa ttttccatct tctatagctt tttctatagt atttaaattg
     1741 tgactagtta taccaatatg ttttatctta ccttgctcct ttgcctctaa aagggcacta
     1801 taagccattt tatctttaaa aagattatca tactcctctt ctttaacatt atggaattga
     1861 tataaatcta taaaatcagt tttaaaatta tttaaactta tttcaacatc tctcttcatt
     1921 gaatcataat ctctggacat acttttagta gctaagaaaa atttatttct ttttccttca
     1981 atggcaattc cgattgcttc ctcacttatt gtataccctc ttgcactgtc aataaagttt
     2041 attccttgtt tttctaactc atttataact aagttagtat catcttgagt aattctttgt
     2101 attggaatgc ccccaaagcc aactctcttt attttcatgt tagtattgcc taaatttctc
     2161 atatctttcc ccacctaact tttaataatt ttttatataa tataaatatg ttacctttaa
     2221 ttatacaaca aattatgaga atctttgcaa tatatttaca tactattcat aatataatca
     2281 tactttatac ccagttaatt tgtatacaat ttttgttatt cctatccatt aatttaaatt
     2341 atcacatttc atgattgtat ctccacctta attatgttga gggcggagta tttcacatat
     2401 ttttaataaa ggtttattta ctagatagta tttcttttat cattttaagc tctctcttgt
     2461 gaccttcatc atcaaaagga gtttctaaga aaaatggtaa atgttttaga ctaggatgtt
     2521 ccataaaatc aattaatgct tttaatccta tctttccttc ccctatagga gcatgtctgt
     2581 cttttttgtc tccaaatggc atcatactat catttagatg gacagttttc aatctttcta
     2641 tgcctataac cttatcaaat tcttccaaaa ccccatctaa atcattcact atatcataac
     2701 cggctgaaaa aatatgacat gtatcaagac acacacctat tttttcttta tgctcaattt
     2761 tgtctattat actttttaat tgctcaaatt taaaacctat ttcagttccc tttcccgaca
     2821 tagtttcaag aagtatagtt atattttcat caccctttat ggcattgttc aatcctttta
     2881 ctattctatc tataccaaaa tctacaccac cacctatatg acttccagga tgaaaacaca
     2941 tgtattcaat tcctaatgag tccatccttc ttatatcctc atctatcacc cttgttgcaa
     3001 attcgtatac atcatccttt gtaccaccca gattcatagt atatggtgca tgtgcaagca
     3061 gtggtgcaaa attattttct tttctaattt cttgaaattt aattatatct ttttcatcaa
     3121 attctttagc atttcctcct cttggatttc tactaaaaaa ttgaaatgta tttgcaccaa
     3181 tatatacagc tgtctcagcc gcattagcaa atccttttgc tattgaaaga tgtgttccta
     3241 atttaatcat attaatctcc ttttatttgt actacgactt gtactcaatt ttaattttga
     3301 actactccac cttaactata tttagccaac atatgaagat ggagattcct atttgatagt
     3361 actttttcac taaaaattca taagctctaa gggatgttct atcccaacta atctcattcc
     3421 tcttttaaca tatttctagc attgatttaa tttatattaa tttttaattt taatatttac
     3481 actttaatta tacccatttt aatcaatttc aaatattata atcttacata ctttgtatat
     3541 tatctaagca cttctcagat agtgtataca tcttacacta tacatattat ttacaaatac
     3601 aataggtata agaaaacaaa aaaatagaga ttaaaaatca ttgttttacc cataccaaaa
     3661 actatttttt gattattaag taaattttga tgttcaatct ctaatattat atctttaatt
     3721 aatccataat taattctcta actaggacat tcctcctcaa gagtaggaac tataaccata
     3781 gctatatcat acttagaacc ttcaacattg tgttgtcttt tatttaaaat ttcatctatc
     3841 tttgacttca tagtgtcact aagttcaact aattcatcat gagtaagaga aatatcatga
     3901 taatcaacta tattttcatt ttctaaaaca tcttcctctg ctgccttata aaaaacttca
     3961 ctcatatttt caaattttga tatgtacaat tcttcttttt cttccccatt gtctaaagaa
     4021 aaattaagta tcctattccc tataaccaca ttttttgcac ttggataata gtacttttcc
     4081 acaatccccg actttatttt ttcctcaact aattctaaaa taccaacttt gtataacatt
     4141 tttatatggt agtttatttt tgcatgaggt tcttccaata attgagataa ttgttttgct
     4201 gacaatggcg atttgtcaaa tgcttttaga atatctattc tacgtggatg cgcaatagcc
     4261 tttatgcact ccaaatctcg taataccaat acctctttca ttgacccctc ctaaaaaatt
     4321 tatttaattc atatttcttt acaatttaat tatatattaa attatatgtt gttgtcaaaa
     4381 aaatcctttc ttaatatttt aaaaaatatt taatttgagt ttatttgaca actcctctaa
     4441 aactttaact cctgcgacgc tgttaccttt tttgtcaagc gcaggtccat aaacaccaat
     4501 ccccatgcgt cccggcacag aagccattat accaccccca actccagatt ttgcaggaat
     4561 gccaacttta atagcaaatt ccccagaagc atcatacatt ccacaagtca tcataaatgt
     4621 cttgacaatc ctagaaacca tttcactcat taaatgctca ccattttcta tatctactcc
     4681 ataatttgca agatttattc caattctcgc taaatctaca gaatctatct caattgagca
     4741 ttgtttaaaa taaaggtcta gaacatcttc tacattccct ctgataaatc catcactttt
     4801 caataagtaa gccatagctc tgtttctatc tccagtcatt ttttcagact tatagacatc
     4861 atagtttatt cctatattat cattttttgc taactttcta aagaaactaa gcattctttc
     4921 ttctttttct tctaaacaac tcccatttat aagggaagta gttactatag cccctgcatt
     4981 tatcattgga ttacagggtt tttttgtgtc attaatttca agtttcatta ttgaattaaa
     5041 tgggtcccca cttggctcca ttccaacgtt tgaaaaaacg tcttcccaat cattatccat
     5101 aagtgccata gcaagcacaa ttggttttga aatactttgt atagtaaact ttgtgctaca
     5161 gtttccagca ctataaagat tattttcgct atctatgata caaattccta aatcatttct
     5221 tctagcgttt tttaattctg gtatgtaact agcgacttgc ccataattag tatacttctt
     5281 attagaactt ataatttctt ttaataatgt ctcatctaac gtattcatat gcacctctta
     5341 tattatgtta tatattctat tttagcacaa gtttgtacta taataaaaca gtgttaaaaa
     5401 aaattatact ttaaaactat tttctacaag aatcaattca tttttcaaac aatttaaaca
     5461 gtttaaatag cttaataatt taataatcta gtaatttagt aatctaataa tccagtaatt
     5521 taaattctta taacgtcaaa aatttctaac ctaac
//
LOCUS       DAEQJM010000129         5503 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.132, whole genome shotgun sequence.
ACCESSION   DAEQJM010000129 DAEQJM010000000
VERSION     DAEQJM010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5503
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.132"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..519
                     /locus_tag="KRQ43_003549"
     CDS             <1..519
                     /locus_tag="KRQ43_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBH2743883.1"
                     /translation="MNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFPVGRLDKDTEG
                     LLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLDDGYKTMPSQL
                     NILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLDESLELGEYRE
                     LTDEEVKLIEER"
     gene            546..1907
                     /gene="rlmD"
                     /locus_tag="KRQ43_003550"
     CDS             546..1907
                     /gene="rlmD"
                     /locus_tag="KRQ43_003550"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH2743884.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMNEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            2430..3464
                     /locus_tag="KRQ43_003551"
     CDS             2430..3464
                     /locus_tag="KRQ43_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HBH2743885.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPYEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKNKKRKKI"
     gene            3551..3754
                     /locus_tag="KRQ43_003552"
     CDS             3551..3754
                     /locus_tag="KRQ43_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HBH2743886.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            3925..5085
                     /locus_tag="KRQ43_003553"
     CDS             3925..5085
                     /locus_tag="KRQ43_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HBH2743887.1"
                     /translation="MKLSKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVIIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
BASE COUNT         2181 a          543 c         1069 g         1710 t
ORIGIN      
        1 atgaataaac ctgatggata tatatcagca actacagata aatatgaccc aacagtatta
       61 gatttaattg atttatcata cttagctttt gaaccatttc ctgttggaag gttagataaa
      121 gacacagagg gattattagt tttaactaat gatggaaagc tttctcatag agttttatct
      181 cctaagaagc atgtgcctaa gacttattat gcaaaaattg atggagtagt tactgaagaa
      241 gatgtagaag cttttttaga aggtgtagtg cttgatgacg gatataaaac tatgccatca
      301 cagttaaata tattaaaaag tgatgatgaa tcagaaatag agcttacaat acatgaaggt
      361 aagtttcacc aagtaaaaag aatgtttgaa agcgtaggca aaaaagtagt atacttaaaa
      421 agattgtcta tgggcaattt aaaattggat gaaagtttag agttaggtga gtatagagag
      481 ttaacagatg aagaagtaaa attgattgaa gaaagataat aaagatacta tagtaaattg
      541 gaggaatgtc tgtgaagaaa aaagatgtta tagaatttga agtagataaa atggaatttg
      601 gtggtacatc tttaagtcaa gttggagata gagttatcca tatgaagggt ggaataagtg
      661 gtcaaaaggt gagagctgga gttaaaaaag ttagaagtaa gaaagctgaa gttaagatga
      721 tagaattatt agagaactca ccacttgaaa ctgaagaaac ttgcaagcac tttagagagt
      781 gtggaggatg tacactattg tctgtgccat atgaaaaaca attagaaata aaagaaaaac
      841 aagttatgga tttattttta aagcaagatt tatttggatt tcagttttta gggatagaag
      901 gaagtccaga aaacaaatat tatagaaata agatggaata tacttttgga gatgaagtaa
      961 aaaatggacc tttgacatta ggtcttcata aaaaaggaaa gcatatagat atacaaactg
     1021 ttgaggagtg tatgttggtt gatgaagact tctcaaagat attagtttct agtgtagagt
     1081 ttttcaatga aaaaaagctt ccttattata gaacaatgaa tcacaaagga tatttgagac
     1141 atcttgtagt tagaaaaggg attcatacta atgagattat ggttaatata gtaacttctt
     1201 ctcaagaaga ttttgatatg aatgagttta aagatatgct tttagggatt gatttaaagg
     1261 ctgagttagt aggtgtactt catactatta atgatggttt agcagatgca gtccaatgtg
     1321 atgagttaag agtattgtat ggaagagatt atatacaaga agaaatttta ggtcttaagt
     1381 ttaagatttc accattttcg tttttccaaa ccaatactaa gggagctgag gttctttata
     1441 gtattgctag ggattttatt ggagattaca atgataaggt tgtatttgac ttgtatagtg
     1501 gtactgggtc tattggacag gttatggctg gtgctgctaa gaaagtgtat ggtattgaga
     1561 tagttgagga agctgttgtt gctgctaatg agaatgctaa gttgaatgga cttactaatt
     1621 gtgagtttat tgctggggat gtggctaagg ttgttaagga tttaaaggac aagcctgatt
     1681 tgattattgt tgaccctcct agaccaggca ttcataagga tgctattagg gatatttgtg
     1741 gatttggtgc taaggagatt gtttatattt cttgtaatcc taagtctttg gttgttgatt
     1801 tggttgattt taaggggtat ggttatgaga ttaagatggt taagtgtatg gatatgttcc
     1861 caaatacgcc acattgtgag actgtagtta aacttattag agaataacag ggtttcagac
     1921 ttttatattg tgtcttaaaa gtagatttgc cacctatttg ccaccataat tatttttggg
     1981 tggcaaattt attctacaat gatttcaaaa atatttacca tctggtttct catgttatta
     2041 gttacatgta aatatgtatc catagttgtt gaagttttag catgtccgag tatatgctgg
     2101 atatctttta tattagtacc attttctaat aacatagtat cagggttttt aaaataaagt
     2161 gtgtattctt ctagagtagt gataattaaa atatcaaata tcactataca aaggaaagtg
     2221 cacccttttt atgtttagca aaaacgaaat attaaaaaaa cttattgaag aatatgatgt
     2281 caaaacaact acagatattc aagatatgct aaaagattta tttacaaata caattcatca
     2341 aatatttcca ttgtcgaatt ttaacggttt aaacataata tattgactga tataataaaa
     2401 tcatagaata ttttaggggg aaatagatta tgtttaagaa aaagttaata gctgttgcaa
     2461 tgagtataac tatgattagt gtagggagct tttcgtatgc tcattcagga agaactgatt
     2521 catcaggagg tcatcgtgat aataaaaata aatctggatt aggaagttat cactatcatt
     2581 gtggtggtta tccagcccat ttacataata atggtggttg tccttatact ggaggaggaa
     2641 gcagttctgg aacaacaact tcggttaata atgaagaaaa gcaaaagagg tctgttggag
     2701 aaaaaggata taatcaaggg tatgaagatg ggtataaagg aaattatagt tcatcaaatt
     2761 atagtggaga ttatagtgat acatatgaat caaagtactc agaaggatat gaaaaaggta
     2821 aggctaaatt agaagaggaa gaaaaggtgg ctaaagagac tggatataat ttagggctta
     2881 caggtgctaa atctaataat acatatgaaa aagaagtttt aaaaaatgct tatgataccg
     2941 gatattcaac tggatacaat gaatataaga ctaaaaagat agaagaatat aaagctaaag
     3001 ggatagagga tagcaataaa gataaagaaa aaatgacatt tgaagaaaac atagattctg
     3061 aatttataga tgcttataat aatgcttatg acgaaataca agaacaatta aaaaatgatt
     3121 acactactca aggatttgag agtgctatca aaggagaaag atttgacaca tcaactatag
     3181 gtaatgttaa atatgctaat tggtttaaag aaggatatga taatggtaag gttaagttac
     3241 ctaaagcaaa agaaagtgta tataatcaag gttacaatga agaagatttt agtataccat
     3301 atgaaatgaa gtctattgaa actaagttaa aaggtgtata tgatgaaggt ttagaaaaaa
     3361 gagaagaaga gaaaagtaga aatgctactt atggggttgg agctggaaca gcagctgtag
     3421 ttgctggagt agtatataaa aataaaaaac gtaaaaagat atagatgcta gatataccaa
     3481 tgatgacaag tgtataacaa atataatttt aagtataaat atttaaaata tagaagggaa
     3541 ggttatatct atgggattta actttaggaa aagcataaat ctaggaggag gactcaaatt
     3601 aaatttaggt aagaagagtg taggtataag tgctggtgtt aaaggtgcta gagtgtcagt
     3661 taattcaaaa ggaagaaaat cagctacatt gagtatacct ggaactggaa tatcatatac
     3721 aaaaactagt acaaagaaac gtaaacctaa ataaatattt gatatactaa gaaatagact
     3781 gttacaaata gtctattttt tagtatatag atttaaaaag tgacaaaatt ttgaaatata
     3841 aactaatttc ataaaggaaa atattctttt atgtagaatt ataatattta agtaatatta
     3901 taaaatttat aggaggattt cattatgaaa ttaagcaaaa cactattggc aatagggatg
     3961 tctgtttcat tattgattgc tagttgtcca acatcaaacg ctcttagttc tattaattca
     4021 ataaaaggta caaataagta tgaaacagca ggtttaatag cagataaaca aaattatgat
     4081 attgcaatac ttattaattc tgaaaatgga ttatctgatg gattgtcagc aagtggattg
     4141 tcaggagcta aaaatgcccc aatattgtta actaagaaag atacaatccc ttcagaaaca
     4201 ttaaaaagat tagaaaaggt aaaagaagta tatctaattg gaggaaaaaa ttcgatagga
     4261 gcatcagttc agaaaatatt aagtgataaa aaaataagca taaatagaat aagtggaact
     4321 gatagaatag atacaagtca taaagttgca aaagaaatag gaagagtaag tacggttaaa
     4381 aaagtaatat taactaatgc ttttaaaggc gaaccagatg ctatgagtgt tgcttctata
     4441 gcagttagag ataaatctcc aatagtatta actgatggaa atactacaag ttttgctaca
     4501 gatggattag aaacttatgc aattggtgga aaagtcagta tgagtgataa gttaataaat
     4561 gaaactaaag caacaagaat aggtggagta gatagatacg atacaaataa acaaataata
     4621 aataaatttt ataatggctc aaaagaattt tacatagcaa gtgggactga tttagtttat
     4681 tctttagttg gttctacaat tgcacaaaaa acacctatag tgttagttgg aaatggaagt
     4741 aataagagta tattaaaaaa tgcaagtaaa ataactgcta ttggaaatat tgatgatgtt
     4801 attataaaac aatgtttaaa tataactaat aatgttgggg attcaaatac aggtattgta
     4861 aaagatacta attcaaataa tacaaacaaa ccaagtaatg agcctagctc taataatcct
     4921 ggattaactg ataaaagtac agtatatgta actcctaatg gaaaatcata tcatctaaca
     4981 aaaaattgtt ctacactaaa aagaagtaaa acaataaata aagtaacatt aaaacaagct
     5041 aagtcacaag gtaaaataga cccttgtaat gtttgtgtaa aataatgtat tagccaaata
     5101 tatattaaaa aagacaatta attaagattg tcttttttat tgaagaaata taaatttata
     5161 ttatgtatta ttaaaaagaa aattattaat tataaaaaat aataataaag acgataagta
     5221 ttaaaatttt atgtttccaa tatttatgat ataattaata tggcaaggaa taaatatttg
     5281 aaaaagctat gagtggtgtt tccatggaag tttcttcact ttcttatgag aggaggtgaa
     5341 aactatggaa aatctaatga tgagtattat aactggtgtt atagccagtt acatttacga
     5401 taaattaaag agccactctg accaatgaac tatacccact gttttataca gttaaaacat
     5461 gtaaaagtgg ttataaagta ctagtgtcaa tcattagtac ttt
//
LOCUS       DAEQJM010000130         5395 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.133, whole genome shotgun sequence.
ACCESSION   DAEQJM010000130 DAEQJM010000000
VERSION     DAEQJM010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5395
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.133"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            43..1011
                     /locus_tag="KRQ43_003554"
     CDS             43..1011
                     /locus_tag="KRQ43_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HBH2743888.1"
                     /translation="MNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDFIVPVFFC
                     IICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINKPTMVMDD
                     LVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLMIALFPFG
                     MVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRSLNQFLCCSKKAFYICVSYLAIFE
                     VLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYARILFLII
                     ILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     misc_binding    1163..1415
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1487..2695
                     /locus_tag="KRQ43_003555"
     CDS             1487..2695
                     /locus_tag="KRQ43_003555"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBH2743889.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     gene            complement(2756..3637)
                     /locus_tag="KRQ43_003556"
     CDS             complement(2756..3637)
                     /locus_tag="KRQ43_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH2743890.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPGRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            4023..4967
                     /locus_tag="KRQ43_003557"
     CDS             4023..4967
                     /locus_tag="KRQ43_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH2743891.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLI
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            5190..>5395
                     /locus_tag="KRQ43_003558"
     CDS             5190..>5395
                     /locus_tag="KRQ43_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH2743892.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGE"
BASE COUNT         1992 a          599 c          897 g         1907 t
ORIGIN      
        1 aaaactttag ttagaaaatt tatgatttat ggaggcagtg ttttgaatac tactaaaaaa
       61 ttaactgaag cagctttatt gtcatcttta ttcatagtag taacaattat agctgtgagt
      121 actggatttg gatatgctat ttacttagat tttatagtgc cagtattttt ttgtataatc
      181 tgcttgaaat gtgatttaaa gtataccatt ttatctggaa ttacttcact tttaataatt
      241 tctctggtac ttggaaatct aggaactgct atttgggcaa gtcagagtgt attacttggt
      301 ataatgtgtg gctatctaat aaataagcct acaatggtta tggatgattt agtatatggt
      361 tcagtatttg gggttattgt aatggttttc attgatatat atgcttcaac attaataggt
      421 tatagtttta tgaaagaatt tcaaggatat agcaaatgga tttattttaa tgggtataca
      481 aattttattt attatttaat gatagcattg tttccttttg gtatggtgtt ttgcatatat
      541 ttattaagtt taattttagg gaataaattg catattttag attctaattc tttaaaaaaa
      601 tttttaatat ttaagaattt tagaagttta aaccaatttt tatgttgctc aaaaaaagct
      661 ttttacatat gtgtttctta tctagccatt tttgaagttc taaaactgtt gaatgttaaa
      721 gttgattctg tttatttaaa aacaatcttt atatcaataa cctatataag tgtctatttt
      781 atcattagag actcatgtat gtcactacaa aactttataa tagctaagtt tagaaaatta
      841 ttatatgcta gaattttatt tttgataata attttattgc tgttttttat atttgatgta
      901 acagttatta gtttaataat tataaacgca tttttaaata agaaaataaa tataagattg
      961 agtcagagta atatagtcaa taaacaaata aatcttttga ttgaaaaata aactttgggt
     1021 attggtaaaa aatataaaaa agtagtataa tgtaaaaaaa catgtatata ataataaaaa
     1081 aggttgacaa aatataaaaa taataatata ttatgagtaa gttaagaaaa atttcttgta
     1141 attgatgaaa taatctgaat atataaatgc tatgaagaga agaagtaggg ctagatttta
     1201 tttaacagag agttccagtt tggtgaaatg gaataaattg atttagtttg aatacatctc
     1261 agagcactat ctctgaaaga taacaaccat taagagatat cggattagta cacgttatag
     1321 tacacgagta tatgtaattg tactctaaga gattaatatc gtgagatatt gatgaactaa
     1381 ggtggtaaca cgtaagcaat gctttcgtcc ttttaagagg atgaaagctt tttttattat
     1441 aaaaaaaaaa ttatagatta tataaatatt ttaggaggaa tgaaaaatga aatcgataga
     1501 cgagcaaatg cgaataatta tgaaaggtgt agatgattta atagatgaga aagagttaag
     1561 ggaaaagctt attaaatcag aaaaagaagg aaagcctatg atagtaaaat tgggtctaga
     1621 cccaagtgct ccagatatac atttagggca tacagtagtt cttagaaaga tgaaacaatt
     1681 acaagattta ggtcatcaaa tagtaataat aattggagat tttacaggaa aaattggaga
     1741 cccaactgga aaatctaaag ctagaaaagc tttaacaaca gagcaagttc ttgcaaatgc
     1801 aaaaacttat gaagaacaaa ttttcaaagt tttagataaa gaaaaaacta ttgtaagatt
     1861 taatagcgag tggttagcca agttaaattt tgaagatgta ataaaattag cagcaactat
     1921 tactgttgcg agaatgttag aaagagaaga ttttaaaaag agatatgaag gacaaatgcc
     1981 aatatcagta catgagttct tctacccatt aatgcaagca tatgactcta tagcattaga
     2041 agctgatata gaacttggtg gaactgacca aagattcaat ttactaatgg gaagatcatt
     2101 acaaagagaa tttggtatgg agtctcaaat agtaataatg atgcctttaa tagaaggatt
     2161 agatggtaaa gaaaaaatga gtaagagttt aggtaactat attggaatag atgaagaagc
     2221 gggaataatg taccaaaaat ctatggaaat tcctgatgaa cttataatta aatactacaa
     2281 tttagtgaca gatgttcatc ctgatgaagt taataaaata gaatctcagt tgaaagaggg
     2341 ttcagtaaat ccaagagata taaagatgaa cttagcaaga gaaatagtaa cattatacca
     2401 tggagaagaa tctgctaaag aagctgaaga aagatttaaa tctgtattcc aaaaaggtca
     2461 aatacctgaa gatatacaaa caattcaagt taaggaagat ggatttgact taatcgaagt
     2521 actagtttct aatgagattg ttaagagtaa gagtgaagtt agaagattag cttctcaagg
     2581 tggagtaaag gtaaatggtg aaaaagtaga ggatttaagc actattgtaa aagagagtga
     2641 attagttgtt caaataggaa agaaaaaatt tgtaaaaatc gagctagtaa aatagagtaa
     2701 agtaaaagca agtctattga gtataaaatg tacattcaat aaacttgctt ttttattata
     2761 ttaaaatttt aaattgataa ccattgtctt taaaatatgt tataatttgg tccaatgcat
     2821 ttactgtttc ttgttttcca taagtatcat gcattaaaag aacaaccatt tctttgcctt
     2881 cagaagattt ctttgcatgt tcaaataatt cttgtgcatt tttcttttta ccttctgcat
     2941 cagcatttaa agcgttccaa tcaattgatg ccatgttttt ctcttttaag tagtttccta
     3001 gaggttccat atttttccat gacatatacc cgcctgggca tctaactaca tttgaggaaa
     3061 aattctttcc taagactttt ttcatagctt catcagtttt gttaagttca tttacgaatg
     3121 tatcgagatt taggcttctg ccaggatata gttttttata gtcatgggta taagagtgat
     3181 gggctattgc atttccttcg tcaaatgttc tttttaaaat ttcattagct ccttttcttt
     3241 caagagaatc acccttaata aagaaagttc ctctaacacc atgtcttttc aagatatcta
     3301 gaacttgtgg agtattagta gtagatggtc catcatcaaa tgtaagaaag actatctttt
     3361 ctccattgtt tgaatagtcg tatttgttaa gtttgtccca aactattttt gcgtcatatc
     3421 catattcttt tacagcttct ttttttgcac caataatagg ttcatttttt tctttttcaa
     3481 ttctttcttt ttctaatctt tcagctttaa gtctttcttg agtttctttc atttcttttt
     3541 ttctagacat gtccgcccat gccatagaaa aaataccaat aactattaca acaagtatag
     3601 taagtgtaac agttttcttt tttctttttt ttaccataat tacagcattc ccccttttgt
     3661 cgaattgtat caaaaatata ttataattat atcgaagaaa gtagaaaaag taaaccgaca
     3721 aagttgtaac taagataact aaagtgtaac ttatatgaca ttatttgcat aatattaaag
     3781 tatcatatat attaaaaata tctataaaaa aatttagtat aggtaaaaaa atataaaaaa
     3841 tataaaaatt tattaaaaag gtgtttacaa aaaatgatta atatattact gttaaatagt
     3901 ggatataaat ttgagctcaa aatgtatgta aatttagatt taaaatactg aaaaaattta
     3961 ctatattaat ttatagtaat gcttatagaa aaactctctt gctgtttagg gggtttataa
     4021 ttttgcaaaa aaataaaaag gagggggctt tattgaaaaa atactttgga gaaataggac
     4081 taatatttat agcaattata tggggaagtg gctttgtagc aacccaattt gcattagacg
     4141 gtgggcttac acctctacaa atcataactt taagattttt cttggcagct ataattatga
     4201 atttactgtt ttttaaacag attcgtgcca atatgggtaa aaaattatta aaagcaggag
     4261 ggattttagg aatattttta tttctagcat tcacagtaca aactattgga cttatgtaca
     4321 ctacaccatc taaaaatgca tttataacag cagctaatgt tgtaatagtt ccgttcatag
     4381 gatttatact ttatagaaga aaacttgata aaataggaat aataagtagt ttggtagctc
     4441 ttataggaat tgggatactt tctttagaag ctgatttctc tattaatttt ggagattttc
     4501 taacacttat atgttcattc ggatttgcat ttcatatatt ctttacaagt gagtttgcaa
     4561 aagataacaa cccaatggca ttgacagcta ttcaatttac agtagcgttt ttaatgtctg
     4621 ttgtagttca aacatttgca ggtcaattaa agatggaagc tgaattatct ggttatatgg
     4681 gaactatgta tctagctgta tttagtacta caattggatt tttatttcag actatatgtc
     4741 aaaaaagagt tgatggaact agaacagcta taatattatc cacagaggct gtatttggta
     4801 caatattttc tataataatt ctaaaggaac ttattacagc aaaattgatt attggtagta
     4861 tcttgatatt tgttgcaatc ataactgcag aaactaaatt atctttttta aagagcaaaa
     4921 aagtgaaact taaagattca gaggagtctt cattagaaag tatttaatat gacaactatt
     4981 tcctaattaa tcaaataagt tatgtattat gtagaaattt gacatcaaaa cttggttgat
     5041 actggtgttt caaagtgata aaattaatta ggaaataaat tttattttta gtgtttaagc
     5101 tataaagtct ggggtatata tattcttgta gcaagttatt aaacttaaaa ataaaaattt
     5161 aattatataa aattgggagg aaattaatta tgaaaaaatt tgtttgtaca gtatgtggat
     5221 atatacatga aggagatgct gcaccagcac aatgtccagt atgtaaagtt ggagctgata
     5281 aatttgaaga aatgaaaggc gaaatggttt gggctgatga acatagaata ggagtagctc
     5341 aaggtgtaga tgcagaaata atcgaaggat taagagctaa ctttactggt gagtg
//
LOCUS       DAEQJM010000131         5352 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.134, whole genome shotgun sequence.
ACCESSION   DAEQJM010000131 DAEQJM010000000
VERSION     DAEQJM010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5352
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.134"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(204..1388)
                     /locus_tag="KRQ43_003559"
     CDS             complement(204..1388)
                     /locus_tag="KRQ43_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH2743893.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1761..4112
                     /locus_tag="KRQ43_003560"
     CDS             1761..4112
                     /locus_tag="KRQ43_003560"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBH2743894.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERFEVQGNKKMKNFPFLMGQGVWKGSDDLVPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4134..4673
                     /gene="nrdG"
                     /locus_tag="KRQ43_003561"
     CDS             4134..4673
                     /gene="nrdG"
                     /locus_tag="KRQ43_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBH2743895.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2092 a          594 c          850 g         1816 t
ORIGIN      
        1 ttataataaa tttagaattt aacttatata gtttaatttg ataatttgat gaaaaaaata
       61 aaagacttac tgatttttaa atctataggt cttttatttt ttatctaaca tttaaattaa
      121 gttgttgaat atatcttata ttacttactt tatatattaa ttaccattaa tacattatat
      181 ctaattacta ttcatctaaa ttattatgcc attattttat atacaaattc ttttaatttg
      241 tctaatccag ataaaaaagt attttcactg caagcatagg atatacgaat atatttatcc
      301 ataccaaatg ctatgccagg aacaactgca acattatatt cttctaaaaa ttgattacaa
      361 aattctatag aaaaactatc tttatattca aatttctcag atactttaga aagatctata
      421 aatatataga atgcgccatt tggattcaca tatcctacat tatcaataga gtctagtttt
      481 gatttaatta aatctcttct tgatttatat gttttaacca tattgtctat gtcaattgag
      541 caatctttca aggctccata ggctatgtat tgtgctgtta gacttgggtg agatataaga
      601 tgtccttgta tagaactcat tgctttagca atcgttttat tagatgcagt atatcctaat
      661 cttaatccag tcattgcagc tgacttagaa aaaccattta tagttattgt tatatcttta
      721 gcttcttcgc ttaatgatgc aattgatgta aattcaccag tgtagcatat tttttcatat
      781 atttcatctg ctaaaatata tattttattt tgtatgcata catctactat ttctattaat
      841 tcatcttttg tataaacact accagtagga tttgaaggat tgtttattac aagaattttt
      901 gttttatctg ttatagattt ttcaagttct tcttttgtta acttaaatcc attttctttt
      961 ttagtatcaa taaaaactgg aacagcatta actaacttaa tcatttcagg ataactaacc
     1021 caataaggct ttggtaataa gacttcatct ccttcgtctg ttaaagctag taaagtattt
     1081 gttattgagt tttttgctcc acttgataca actatttcgt ctattgaata gttacagtta
     1141 ttttcttcaa taagtttttt acagatttcc tctctaagta tttttaatcc tggaactaaa
     1201 tcatatttag tgtaatcttt atttaaagaa tcaataccat aagattttgc gttattaggt
     1261 acattaaaat cgggttctcc tatactaaga tttattactt taactccatt actttccatt
     1321 tctttaactt tagaactaat acctattgtg taggatggtg ttataaagtt tagtcttttt
     1381 gataacataa aatgcctcct tttaaattat tatttatatt atacgacaaa tttaaagaat
     1441 ttacataagg aaatttgtag atatatacat taatatatat aatagcctac actttttgcc
     1501 taaaattagt gtaaaaaaaa gagaaaaaaa ttttaacttt caaagttgtt agaaacgcta
     1561 ctgttcaaaa tatccacata gtatttgcaa tgatttgcgc aagtttgact attatgtaca
     1621 aatttggtaa tcttaatata gcaattatta agataatccc tttaacttag ttgaagggga
     1681 tttttttaga cttaacatac tacatatagt ggtattggga ttaataaaat acaatatata
     1741 gtaacaggag gtttttttaa ttggttgaat tcgtaaaaaa aagagatgga agagtaattc
     1801 catttaatga agatagaata acaagagcta tatttttagc agcaacgaat gttgcagaaa
     1861 gagaaggaat agtacctgat tataaattat ctgagcaatt aactcaagaa gtaataaagt
     1921 ttttaaatca taaatactca gaatcagttc caagtgttga agatatacaa gattctgtag
     1981 ttaaggttct tatagaaact ggccatgcaa aaactagtga agaatatata atatacagaa
     2041 ctgaaagaag tagaataaga aattcaaaaa caagattgat gaaggcaata gaggaaatta
     2101 cctttgaaga tgcagaagat gctgatataa aaagagaaaa tgcaaatatt aatggtaata
     2161 cagcaatggg aactatgtta caatatggaa gcactgtatc taaagaattt tgtaaaacac
     2221 atatattaaa accagaacat tcttttgctc atgataatgg agatatacac atacatgata
     2281 tggatttttt aaatatggga acattaactt gttgtcaaat agatgttaaa aaactattca
     2341 atggtggatt ttcaacagga catggctttt taagagagcc acaagatata ataagttatg
     2401 gtgcattagc tgcaattgct atacaaagca atcaaaacga tcaacatgga ggtcaaagta
     2461 taccattttt cgattatgga ttggctgaag gtgtatataa gacatttaag aaattctaca
     2521 taggaaattt agctaaagca ttgaagttat ttaaaggaat tgaaaataat gatgtgataa
     2581 agaacatagt atataataca gagaaagaaa caaatcaaaa agttggtctt aagagagatg
     2641 aattgtatct aaacttagaa aaagagaaat taatacagac ttttgatata gatgatgaac
     2701 ttgtaaataa gatgcaaaac tttgcatttg aagaatcgta tagagaaact gataaaaaaa
     2761 catatcaatc tatggaagca tttatacaca atctaaatac aatgcactct agagcaggtg
     2821 cacaggtacc attttcaagt gtaaacttcg gaacagatac ttctgaagaa ggaagaatgg
     2881 taactaagaa tcttctatta tctcaagaaa gaggtttagg taatggagag acaccaattt
     2941 ttccaatttt aatatttaag gtcaaagaag gcataaattt aaatcctgaa gaccctaatt
     3001 atgatttatt taaattatca tgcagagtat cagctaaaag actatttcct aattttagtt
     3061 ttttagatgc gccttttaat gcaaaatatt ataaaaaagg tgaaccagat acagaggcta
     3121 catatatggg ttgtagaaca agagtactta gtaatgtgtg tggttcagaa acagttagtg
     3181 gtagaggaaa catatctttt actacagtaa atttaccaag attgggtata aaacatggta
     3241 ttataaataa tgaaaaggct aatttagatg gtttctttga agaattagat gagaagataa
     3301 acttaattat agaacaatta ttggagcgct ttgaggttca aggaaataaa aagatgaaga
     3361 attttccatt cttaatgggg caaggtgtat ggaaaggttc tgatgattta gtaccagaag
     3421 atacactaaa agaagtaata aaacaaggaa cattgacaat tggatttata ggtttagcag
     3481 agtgccttat tgctcttata ggtaaacatc atggagaaag taaagaagct caagaattag
     3541 gattaaaaat agtgtcacat atgagacata aaatggatga agcaacggac aaatataaat
     3601 taaatttctc cttaatgggt actccagcag aaggtctttc aggtaggttt actaaaatag
     3661 ataaaaaagt ttatggagaa attaaaggta tcacagataa agaatattat actaattcat
     3721 tccatgtacc agtttattac aatataagtg catatgataa aattgagata gaagctccat
     3781 accatgaatt gactaatgca ggtcatataa catatgtaga gttagatgga gatccatctg
     3841 ataatttaga ggcttttgaa actgttataa aagctatgaa agatttgggt ataggatatg
     3901 gaagtataaa tcatcctgta gatagagacc caatatgcgg tttttcaggt gtaataacaa
     3961 gtaatatatg ccctgtatgt ggaagaaatg aagatgaaag tgacatcaaa ttcgaaagaa
     4021 taagaagaat aacaggatac ttagttggta cagttgatag atttaataat gctaaaaaag
     4081 cagaagtaag agatagagta aaacatagat agttttattt gggggaataa gttatgaaaa
     4141 taagaatgtc atctactata agttatgaca gcatagttga tggaccagga ttaagaatgg
     4201 taatatggac tcaaggatgt attcataatt gtaaagagtg ccataatcct cagacacatg
     4261 atttatgtgg aggattttat atggatacag aagaaattat aaataaagtc aaatcattga
     4321 aattacaaaa aggcattacg ctatcaggag gagaaccatt tttacaacca gaaccattag
     4381 aagaaatagc aagagaagct aaaataaatg ggttagatgt atggtcatat actggattta
     4441 cgtttgaaca actgttagat aaaaaaaata gagcgtattt taaaaattta aatttactaa
     4501 agcaaattga tattttagtg gatggaaaat ttatagctga aaaaaaagat ataagcttaa
     4561 agtttagagg gtcatcaaat caaaggataa ttgatgttca aaaaagtttg aaatataaaa
     4621 aagtgttttt ggttgagcaa tatatgaagg atgatttatc tatagcagaa taaaatataa
     4681 ataaacagga ttaaatatat gcatatattt aatcctgttt attttcatat aatatttcaa
     4741 gtttgtataa tgtaacaatt aaaccaaaag actcattgta tatttgaaat taagtttttt
     4801 atagtttata ggtgttttat gtggattacg aatgatatag tatcgataca ttatttaatc
     4861 gattcttatt ccaagaaaca attaatttat agaaattctt aattgttaca atataaatat
     4921 ctagataagt tataagatac tgataaataa tttataaagt ttattaatct aatattgtgt
     4981 gtgaatgtta agtggtcaag tagtctaaaa aatgaaaaag atttaaaaaa gtgttttaac
     5041 taaacacata agtgttaaat tcatgtataa gtataggtta gatacataag aaataattat
     5101 gtaatatcta tctttgtaaa aaaatattaa attttgtaat ttgtggataa atatgtttat
     5161 aatgtggata atatttaatg taataagtta aagcaatatg aatcaactgt ttataatgtg
     5221 gataatatta taaatgtatg aataattgca gtatttaaaa acaaaaaaag ttaaaaaagt
     5281 tgttgactct aaaagaaaaa gttggtatag taatacttgt cctcaagaaa agggcaaaca
     5341 aataaagcat aa
//
LOCUS       DAEQJM010000132         5295 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.135, whole genome shotgun sequence.
ACCESSION   DAEQJM010000132 DAEQJM010000000
VERSION     DAEQJM010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5295
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.135"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            6..908
                     /locus_tag="KRQ43_003562"
     CDS             6..908
                     /locus_tag="KRQ43_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH2743896.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIATF
                     GKLLIPFIMAGILGIVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTSHIF"
     gene            1517..2530
                     /locus_tag="KRQ43_003563"
     CDS             1517..2530
                     /locus_tag="KRQ43_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH2743897.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKTFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFEIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            2886..3455
                     /locus_tag="KRQ43_003564"
     CDS             2886..3455
                     /locus_tag="KRQ43_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH2743898.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKSIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(3792..5129)
                     /locus_tag="KRQ43_003565"
     CDS             complement(3792..5129)
                     /locus_tag="KRQ43_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH2743899.1"
                     /translation="MDTYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
BASE COUNT         1956 a          524 c          863 g         1952 t
ORIGIN      
        1 gaaatgtgtt gccacaagat tattatggat taatagtgat tttaggtgtt attcttggag
       61 ttatgggggc attttacaac tggtttactc tatatgtgca gtctttatac aagaagattc
      121 ctaaaattgc tacctttgga aaactgttga ttccatttat aatggctggt attcttggga
      181 ttgttatgcc tgatgttctg gggagtggac acaatttagt tgaagaactt acaagtcatg
      241 aatatatttt tggaatggtt gttttgattt ttgttatacg ttttatattt tcggctgtta
      301 gttttgggtc aggtgcacca gggggaatat tttttccatt gcttgtttta ggagcattta
      361 taggtggaat atttggtatg gtaggtgtta aagtttttgg aatgaatccc gattatgtaa
      421 ataactttgt gcttttggct atggcaggat attttacagc tattgtgcgt gcccctttga
      481 ctggtatcat attaattttt gaaatgacag gttctgttag tcaaatgctt tcactatcag
      541 taatttcaat tgtggcatat attgtggcta cacttatgaa gtctaaacct atttatgaaa
      601 gtcttcttga gaggttactt gaaaaaaatg gagaacctgt acataaagag aggggcgaaa
      661 agatactaga ccagttctct gttatgtttg gctctcctgt tgcgaacaag gcaattcagg
      721 atgtacagtg gcctgaaaat tgtcttttgg tagcaattca aagaggtgga gaagaaatta
      781 ttcctagagg taagacaatt cttagaccaa gtgatgtaat tgtgactatg acagatgaga
      841 gagatagtgg tgctgtgtat gataagatgg aaaatttgtg taaagaacat acgtcacata
      901 ttttttaggg ataatgatga atgtttaata atgatagaat atttaatgaa gatttgatta
      961 aaaaattggt aatttgaaag agagttaagg aattaataga aaatgaaaat gtgatatctt
     1021 agatgtaaaa gagtttgaag aaaataattg tatatatttg ttaatgagat tatatggact
     1081 aatggtatat ttatactgtg ctaaaagttg cactattgta tgaggaatgg gaataaaggg
     1141 tttgaaaaaa taggtagaag atttttcaga tattcttatt gggatatttt aattaatata
     1201 ttttaattgc gatattttgg gaagaataga atttatttat aaatgaaaat aattaaaagg
     1261 ggttaaggtt gtattagccc cttttgctta tagagtttgg aaatggtatc ttgatagcag
     1321 ttgttttatg cttattatat tttattacat attttaaaat taaccttatc actcctaaat
     1381 cattattcta tcaactttta aaacactttc aagacaatca cctattgaaa acaaagttaa
     1441 ttaaaaacct acatatcagt ttagtattcg tgtagatgat tatataaata taaaagtata
     1501 agaaaggtga gtatctgtgg ttagttcatt tttaaatgat atctttagaa caattttagt
     1561 aagttgtatt tttatagtta ttttattagt ctttagaata actttattta agactttcag
     1621 taaaaaattt aattactata tatggcttat tgtgattatt aagctatcat taccatttat
     1681 gaattatact tttatattta atgagtcaaa atataatggt aatattaata agataagttt
     1741 aggcaatttt aatagtattt ctattgtata tagtactgtt ttagtctctg tttggattgc
     1801 tattacgata ttttatttag tttatacttt attgaaatat attaagctta aaaatatgat
     1861 aaatgatttg tcttatgatg ttgaggatga taagataaaa aatctttatg aaaatttatt
     1921 aaaagagctt aagataaata aaaaaatacg gcttaaatat tcatatgaag ttgaaagtcc
     1981 agtatttttt aattcgtgtg tcattttacc accatgtgat tatacattaa aagagttaaa
     2041 ctggatattt aggcatgagt tgatgcattt taagagtaaa gacctttaca ttaagtattt
     2101 ggtgatattt ttaaaatgtg tttattggtt taatcctttt gtgtatataa tggagaagtt
     2161 tatagatttg gattgtgaat tttattgtga tgaaagagtt ttgaagaatt gtacgataga
     2221 agagaagcag gattatgcat tgacaataat tagtgcaatg agaaaaggtt caaatagttc
     2281 aaataaattt gtggctggat tacataagga gtcagatatt aaaaaaagag tgtttagtat
     2341 gtttaatgaa aagtacagaa atggtatttt gatagcagtt attttatgtt tattatcttc
     2401 tattacatat tttgaaattg atttaattac tactaaatca atattttatc cactttcaaa
     2461 acaaacacct attgaaaata gaactaattc aaaacctaca tatcagatta atgtttatat
     2521 agataattaa aaaatacaaa gtttaacaag agattaatat aaataatttt aataagtatc
     2581 tttcacatat gttaaattta ctttaattat attaaagcca atgaattatt ctttagaagc
     2641 tccaatgcca gtaaatacag gtaaagaaaa atcttttact acaattgtaa attaaaaaat
     2701 attctaatat ttaaagaaat gcaaaagtgt aagaagggta aaaatctgtt ataatacatt
     2761 aaaaactaaa tttagaaaaa tttacataat tagaaaaatg atttgataaa aaataaagtt
     2821 aaatattaac taagtaaatt tgaaaaagaa aaaatataaa gtacaaattt aaaaggaggt
     2881 aactaatgaa aaagaagttg gaagatatga ctttagagga gttatggaac ttgtttccta
     2941 tatttttgac tactcacaaa gaatgttgga aaaattggtt taaagaagaa caatatagac
     3001 taactggaat attgccaatg caaaaaattg ttagaataag tcatattgga agtacttctg
     3061 tgagtacgat ttatgccaag tccattgttg acatactgat tgagataatt cctgattata
     3121 atatgaaaga tattaaagat ttgattgagt cgaatggata tatttgtatg tctgagagca
     3181 gtagtaggct ttcacttaat aaagggtata cagtagatgg gtttgaagaa cgcgtttttc
     3241 atttgcatat aaggtatgta ggtgataatg atgagttgtt ttttagagat tacttaattg
     3301 accacccaga tgttgcaaag gagtatgaaa aacttaagtt ggacctttgg aagaagtatg
     3361 agcataatcg tgatgcttat acagatagta aactagattt tgttagggag tttactgaaa
     3421 aggcaaaggt gttgtattct aatagatata attagaaata ggtacaatta gatatttatc
     3481 ttatatatcg tattatattt tttaagaaag taattaatag aaaaaggggt tgtttcaaaa
     3541 tggagagata aatccctttt tcattgttga aatgataaaa atatatttga tttcatgtaa
     3601 aaaagagtgc ctcatcaact aaaaagttta ttttgagaca cacacatttt tattaaggta
     3661 aataaaaata tcacatttga ttaaatttta agttaatgaa tatatgtgta aatatttaat
     3721 tataagttat tataatttta catagtataa aacaatctaa tttgtattat ataagataat
     3781 ctaattttag actaaaataa tctaatataa agaaatagag aaaattcatt ctcagtataa
     3841 gagatatcca attttccatt gtacttatta acaatttctc taatattctc aataccatat
     3901 ccgtgagaat tactatcttt tttatctgaa ataaatagtt cttgttttct attgatagga
     3961 tttaccttgt tgtttgtcaa taaatagcta aaatactcct tctcacaacg tgcctttaat
     4021 accacttttc tatttgacaa atcaggaatt ttcaaagatg cttctatagc gttatctaaa
     4081 gaatttgaaa aaatagtaca taaatctata ggttctatac ccaagtgatt gtctatatct
     4141 atattaaagt gcacatcaac accattttct tccaaacttg tatgacgaag atttaaaatt
     4201 gagttaagag cttggttttt gcaaaattgt ttgccactaa gagtacctat acctattttt
     4261 aactgattaa aatacttttt agctccagca atatcttcaa tttctaaata cgattcaatc
     4321 atttgaaagt gattattcat atcatgtcgc attttgcgta tttgaatttg ttgattttct
     4381 agtaagttat agtatttttc ttttaggtga tttgcttgtt tttctatctt catctttaca
     4441 ttttcaatca atggctgtaa aagaagtatc acaccgatat ttgccagaat tgctgacaag
     4501 atgattagat aagtgccata aggtaagttg cctaagataa tattcttatt actacccata
     4561 gggattaaat tagtaggtgg cagaataata gcaattaata ttgataaaaa tgaagatata
     4621 cataccatat caataaaaat ccatatttta tttgataagt attgttttat attgaccaat
     4681 ctattcttta ggaaaatatg tattaaaaac caaaataata atttaattag agcagaaatt
     4741 atctggacta ttgaaagtat taaaatatat tcttttgagt gtataagttc ctcatatata
     4801 gggttgttta taaaaagaaa attaagccca attataatag gataaagtat catgacaact
     4861 gatattatag gaattaattt gcttttgcta catattataa gtagtataaa atatccgaat
     4921 agtgtaaaca aaatatttac ggggtcggaa agccatatta tcatttgact aataatagag
     4981 tagcccaaaa tcaatatgat tttgaaaatc caatgattcc taaagtctat aaaataggaa
     5041 gtcaacttat aaagaaaaaa ggctatgaaa atattgatta atattagaat aaaatttatg
     5101 cttgtagaga ttaaagaata agtgtccatt taatatacct ttctattaat taagattctg
     5161 gaaactaagt tttaaaaaat taaatcttaa aaattaaaat tctggaaatt agatttcaaa
     5221 gaattgattt tgaaaaataa aattctagaa attaagcttc aaaaaattga gttttgaaag
     5281 attgaaattt taaaa
//
LOCUS       DAEQJM010000133         5166 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.136, whole genome shotgun sequence.
ACCESSION   DAEQJM010000133 DAEQJM010000000
VERSION     DAEQJM010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5166
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.136"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            129..1655
                     /locus_tag="KRQ43_003566"
     CDS             129..1655
                     /locus_tag="KRQ43_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH2743900.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NNGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            1683..2234
                     /locus_tag="KRQ43_003567"
     CDS             1683..2234
                     /locus_tag="KRQ43_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743901.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPYYSKKI"
     gene            2763..3806
                     /locus_tag="KRQ43_003568"
     CDS             2763..3806
                     /locus_tag="KRQ43_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743902.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKG
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            3917..5059
                     /locus_tag="KRQ43_003569"
     CDS             3917..5059
                     /locus_tag="KRQ43_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH2743903.1"
                     /translation="MSEEKNPKENTLDEPKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
BASE COUNT         2180 a          424 c          921 g         1641 t
ORIGIN      
        1 tataaaacaa gaaaactaag tgatttttca tttagctttt tattaagctt attttttata
       61 ctatttataa taaataaact ccatgatggg aaaactatta ctatttaata tgtaaaggag
      121 tattttaaat gaatgaatca tattggtttt taaactcaag tccaaaagaa tataacaaat
      181 taggtgaaaa tataaaaaca gattgtctta tagtaggtgg tggaataact ggattgacaa
      241 ctgcatattt attagcaaaa gaaggtaaaa aagtagtgct tgttgaggct gataaaatag
      301 gatatggaac ttctggaagg aatactggta aggtaacttg tcagcatgat atattttact
      361 ctaagataga gaaaaaatat ggattagata aagcaaaatc atattataat gcaaataatg
      421 aagctttaaa tttagttgaa caaataatag aagaaaacaa tataaaatgt gattttaaaa
      481 gggaaacttc ttttgtattt acagaaaaag aggatactat aaagaatatt aaagatgaat
      541 atcgtacatg taaaaaaata ggaataaatt gtgagtatca tgaaactata gaaaatattc
      601 cattagatat aaagggggct attagtttta ctaatcaagg tcaatttaac ccaaagaagt
      661 atattgatgg attggcaaaa gcagcagtaa atttagggct aaaaatatat gaaaatacac
      721 cagtagtaga tcttgaaaaa ggaaaaatat gtagggttaa aacaagagaa gataatataa
      781 tagaagctga gaatgttata atttcatctc atagtccatg gtatgatgga ttgaattttt
      841 attttgcaaa agaatatgca gagcgtgctt atttaatggt tgcagttttg gaaaataaat
      901 tagcagatgg tatgtttata agtatagatg acccatcaat aacttttaga caatataata
      961 atggaagtga aaatttactg atttttggag gaggagacca taaagttggc cagggaggaa
     1021 ctgagaaaga aatatttgat gatttagagc attatggtaa agaagtcttt aaggtaaaag
     1081 attttaaggg gaaatggtct gctcaagata atatgagttt tgacaatgtt ccttatattg
     1141 gttatatcaa caaaagagaa gacaatattt atgtagctac aggattctct aaatggggaa
     1201 ttactaatgg aactgctgct ggaataataa taaaagattt gataataaat aataattctg
     1261 attataaaga tacttttaat ccatccagat taggtagcta cttttcaaaa gattttataa
     1321 aggaaaatgc aaacgtagca ataaattatg taagtggaaa attaaaaata ggtagtggag
     1381 atatgcctaa aaataatgga gaaggaaaga ttgttaatat tgatggaaaa agatatggtg
     1441 tatataagga tgataatgga gatttttata ttgtagacac gacatgtact catttaggat
     1501 gtgaacttaa ttttaacagt gaagaaaaaa catgggactg tccatgtcat ggttctagat
     1561 ttgactataa gggaaatata cttgaaggac cagctcttaa gccattaaaa ctttatggac
     1621 atggtgataa tgatgttaat cctaagttat tataaaatta tttttaggaa ggtaaagtgt
     1681 atatgaataa acttttaaag ccaataacta tactattgta tatagtttat attttatctg
     1741 ccgtattttt tgtagcaaac aaagaatatg gaagtctagg tctagtagca attagtttag
     1801 ttggtacttt cattttgagt tttataaata agcaaactga aagattattg agtaaagaat
     1861 tatatataat gcttgcttta tttataatgt tttcatcatt gttaggtact tgttttaatt
     1921 tttatgatat aaattattat gatgattttt tgcatttatg gtcaggtata atatcttgta
     1981 ttgtggcttt ttctataatt aaatactttt atacacaaag agagataagt aaaatgagta
     2041 aagtgttttt agttatattt ttatttatgt ttagtatggg agtagcgagt ttatgggaaa
     2101 taggtgaatt tttaatggat acttttgttg ggactactac acaggccggg gggttagaag
     2161 atactatgat tgatatggta gatgctttaa taggcacaat tataactatt ccttattata
     2221 gtaaaaaaat ctaatatata gttttaaatt ttttatatta attataatgg atttaattaa
     2281 tcatgttgag tttcaaggtc tatatgatta attaaatcca tttttgttat ttataattat
     2341 tattgaatgt atttttacat ataagatata aggtgataga tagaaattgt tggattatgt
     2401 aaataattaa tatataatac cattatgggc aataaataca aatcaaatga taatatagtc
     2461 tatttatgta aatgttatat tgtatcctaa gtataatagt aagttttttg atagtggtgt
     2521 agaaagtaaa aatctactag cctaaattga tgtatggatt agtttaggaa cagtaattgc
     2581 atatcttaag tttgatgtca tgttgggcta ctagaaatag gtcatctttt tcacttgaat
     2641 atcttttctt taaacatgag gagtatcata tcaaaaacat atgaaaatta agtgatttat
     2701 aagaacagta atattttata tgatagtata gaatagtaat aaagtattag gaggaacatt
     2761 gagtgttaaa aaagtggttt ggtattgtga aaaaaagaca aaaaagtgag tcagtaaaag
     2821 aagaaggtga agtaatatta aaaaacgaaa aaatattatc tgaagaaaag ttgatagatg
     2881 aagaaggagt tgtagttaat attgataatg aaatattaac taaagtagaa gtagtaaatg
     2941 atgataatga aatagaagaa aaaataatag aagaagattg gttaattagt gaaaatacca
     3001 taaaattaga tgataaagaa gcaattatta atgataaaaa catagaatta tgtaaaaaag
     3061 aagttcaagt tgaaagtgaa aaaataggtt taaataagtt tgaaggactt gaccaaaatg
     3121 aaaattataa tctagaaaaa aatgttattg aagaaaaaaa agtaagtgaa tgtttgacag
     3181 aagaagattt agagtacata aaagaaatta aaataaaaag aggaaaaagt ataaaagcta
     3241 taaacttgta tactaaagaa gagtgggttt ttgacactca tatacagtgt agtaaaaaac
     3301 tcaaagttcc attaggatac ataagagaaa atttaaaata tggatatatg gattactttg
     3361 gagatgcaat aaattattta agtgaagtat taaatataga tgaatactgc aaaggtgaat
     3421 ggagctatct cgataatagc aaatctccat ctgagatatt taatattcta aacaataaaa
     3481 tatttagtat aaggctttct aatgaaaaaa gaaatgaaat tttgacaaat gataaaattg
     3541 aagcattaaa aatgaattat agatttgaat gtattgatga agaatatgat gaatatttta
     3601 aaaaatataa gtctataatc aaaaggggtg gaaagaaaaa agttgaatta gtaaataaaa
     3661 aaggtgacat tttagaaata tttaagtctt tagaagaatg tgccatttat ttgcaaaagg
     3721 aaaagaatga agttatacaa atgttaaaat atggagatac aaaagtagga agaaacttta
     3781 taaggtatag tttgagaagt atttaatttc attttaaatt cataagagtt tcatttctga
     3841 ttcacacatt taatattatt ttaatgtaaa ataataaagg tgaagtattg cacaattaaa
     3901 attaaggagg gtattaatgt ctgaagaaaa aaatccaaaa gaaaatacat tagatgaacc
     3961 taaaaattca gataatgtaa attctaaaaa agatgatgtg tcagatgaaa aaaatactga
     4021 taacaaagtt aaaaaaaggg aaataaagct aaacaacaaa acacttaaag ctattgtagc
     4081 aattgttgca gtaggagcta tatgtttagg tggaggctat gtttttggta aagaagctgg
     4141 aagaaaattg cctgctactt caaaacacta taatagcagt gaggtagtag ctactattgg
     4201 ggataaaaaa ataacaggtg aaatgttaag aaagagaatg gagccattat tttatttaaa
     4261 tgcaaaaact actatgactg atgacgaaat acgttcatat gaatcaaata tgattgaaac
     4321 tatgattaca tctgatatat tatcctctga agcagcaaaa gagaaaataa gtataactaa
     4381 tgaccaacta gatgctcagt ataataattt aatgagtagt atagaatcag caatgggaat
     4441 gactaaagaa gagtttttaa aacagtttga tttgactgaa aaatatataa aagatgatat
     4501 gaaaaaagag ctagtagcat caaaatattt aaatgaaaaa tcaaaagtta ctgataaaga
     4561 agcagagaac tattacaata aaaacaagag caattattta caagttagag cttcacatat
     4621 tttaataaaa actgttgatg ataaaggtaa gcaagttagt agtagcaaaa aagctgaact
     4681 taagaaagaa gctgaagaaa tacttaaaaa agcccaagct ggggaagatt ttgctactct
     4741 agctaaaaaa tattctgaag atagtagtgc agaatcaggt ggagatttag gtttctttgg
     4801 taaaggtcag atggtggaat cttttgaaaa agcagccttt gcattgaaga agggagaggt
     4861 atctaacaaa cttgtagaaa gtgattatgg atatcatata attaagaaaa ctgatgaaaa
     4921 atatcaacca tttgaagagg taaaatcaga tttagtaagc agtttaacat cagaaaaaca
     4981 aaacctactt atacaaaatt taaaagaaaa atataatgtt aaaattacag ataaatatca
     5041 aatgaaagct aaagaataga taaagtcaat ttattaaaaa aaagaaaaat taactgtatg
     5101 gataaaagct atttttactc tcaatataga gagtctaaag tagcttttat tattttgtaa
     5161 taaaat
//
LOCUS       DAEQJM010000134         5163 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.137, whole genome shotgun sequence.
ACCESSION   DAEQJM010000134 DAEQJM010000000
VERSION     DAEQJM010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5163
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.137"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            353..1042
                     /locus_tag="KRQ43_003570"
     CDS             353..1042
                     /locus_tag="KRQ43_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2743904.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYFVKTAVDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSEDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNTIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            1042..1959
                     /locus_tag="KRQ43_003571"
     CDS             1042..1959
                     /locus_tag="KRQ43_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH2743905.1"
                     /translation="MELFLVVISIVLFAFYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATLEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            2032..2958
                     /locus_tag="KRQ43_003572"
     CDS             2032..2958
                     /locus_tag="KRQ43_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743906.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNDVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFSKKVAETDFEILKKIGTIIENPYFYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     KNQIGINSIGRKQSSLEDYFFQTTGTGGIETL"
     gene            2955..3635
                     /locus_tag="KRQ43_003573"
     CDS             2955..3635
                     /locus_tag="KRQ43_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743907.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSILGILLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLVFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            4080..4781
                     /locus_tag="KRQ43_003574"
     CDS             4080..4781
                     /locus_tag="KRQ43_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH2743908.1"
                     /translation="MNNSFLDKLIETKELKNSLYNVLKHNFLYHSNKIEGSTFTTEAL
                     ALLLDKNVVTGRHTLDDVQETVNSSYVFDTVIDSLKEKITHNFLRNLHSSLIFNTTLH
                     SRGMAGIYKTIPNMILGTDVSIAQPFEVEPKLDELIEWYYSQSEVSIKVIAEFHYRFE
                     LIHPFQDGNGRIGRFVMLKQMLENNLPIKIVSWDSEDLYRNSLNSCSLGNYVPLIEYL
                     SSLEDFREVYKMLWK"
BASE COUNT         1986 a          543 c          801 g         1833 t
ORIGIN      
        1 attatttaaa atcccaattt gattattttt aaagaaacta tattctgtat aaaactagaa
       61 tgtggtttct tttttatgta taaaatattt tttagcaaaa gttaaaaggt gttttataat
      121 ataaaatagt taattgtaga tgttaataaa agaaaattat gtatatttca gataaagata
      181 agagagtata ctatatttta attatttttt caataaaact tattgaaaag aactttaact
      241 tagaagagta tcaccaaatt gcagatacaa tatcataagc agttatttat tgacaaccct
      301 ttttaataaa tatatcattt gaagtatact gacgaaaagg agttgaataa taatggacat
      361 cttattggtt gaagatgata agaatattcg agaaatggta tacgattttc tgattagtga
      421 gaattatttt gttaaaactg ccgttgacgg aaatacagct attgaaatat ttaaaaatta
      481 ttcatttgat attattttac tggacttgat gttaccaaag tctagtggtt ttgaagtatt
      541 aaaatatata cgaagtgtga gtgttgttcc tgttattatt actactgcga aagatagtga
      601 cacagataaa atgctagggc ttaatcttgg tgcagatgat tatattacaa agcctttttc
      661 aatcgtagaa ttgcttgcaa gaattaaagc taatattaga cgtgcaacgg tgtatagcag
      721 ttcaagaaac tctgaagata tggttattca gtataaagat ttgattataa acatatcaaa
      781 atatgtagtt tcaaagaatg gaattgactt aaacttaaca catacagaat ttgaaattgt
      841 taaattacta gcgactaatc aaggacgtgc tttttcaaag gaacaattat acaacactat
      901 ttggaaagaa ccttattatg gaaatgaaaa tgtgctaaat actcatatta acaggttaag
      961 aaataaattg tctgatggta tagaaaaaaa taattatatt aaaactcttt ggggaattgg
     1021 ctacaaaatg gaggaagaat aatggagtta tttttagttg taatttcgat tgtactattt
     1081 gctttctact taaaagaacg aaataagtca aagaaaatgg aaagtgatta taagtatatc
     1141 aattcaagac ttcgtgatat aacaaatgat gatgaaatta attatatttt agtaccatct
     1201 gatatttcga ttgtaaaaga aacagcagta gatataaata aacttcttga aaagttttac
     1261 agtaggcaaa ttaattataa tagaagtgaa aaagcgatat tgcaaatatt tacaaacata
     1321 tcacacgatt tacgaactcc catcacagta ttaaagggtt atattgaaat gctatatctt
     1381 caaagtcaaa aagaagaatt atcttcttca atgagagcaa ctttggaaaa aatgcaaaca
     1441 aattcaaatg agcttgttaa ttcaataaat aacctgttta atatggcaaa aatccaatct
     1501 ggagatatga tattaaatct tcaaaaatcc aatctaacac aattatgtca tgagattatt
     1561 ttagagtttt atgatttact agataaagaa aactttaatg ttgaagttaa tattgaagat
     1621 agacctatat atgcaaatgt tgacacagaa gcattacaac gtatactcaa aaatttaatt
     1681 gataatgcta taaaatatgg ttcagatggt agatttttag ggatttcact atatgaaaag
     1741 gaaaaacatg tttttataga tattgaggat aaaggttcag gtatttctga aactgaaaaa
     1801 gagcatattt tcacaagagc ttatactgct gacagaaaaa aaggcaatgg tttaggtttg
     1861 gctatttctc aagggcttgc aaactctatg ggaggttcaa tttatgtaaa tagtagacct
     1921 aatgtaaaaa cagtttttac ggtaaaattg aaaagttaga aaaaagttag atttaaaaga
     1981 gagaaaagat aattttattt tgtatactgt ttttagaaag gagggagtat gatgaactat
     2041 atcatagaga cccatcaatt aaagaaaata tataaagata aagctgttgt taatgatgtt
     2101 aatattcatg tgaaaaaggg agaaatttat ggatttgttg gaccaaatgg agcaggtaaa
     2161 agtacagtaa tgaaaatgtt gctaaatctc gttaagccaa attctggaga aatagttatg
     2221 ttcagtaaga aagtggcaga aactgatttt gaaatattaa aaaagattgg tactattatt
     2281 gaaaatcctt atttctatga gaatttgact gctaaacaga atcttgattt acactgtgaa
     2341 tatatgggtt attataacaa agaacatata tcagaggtat tggaatgtgt cggattgtca
     2401 aagcaatcaa acaagaaagt ttcaaaatat tctttaggga tgaaacaacg tcttgcaata
     2461 gctagagcaa ttcttactaa accagaatta ttgattcttg atgaacctat aaatgcactc
     2521 gacccagagg ggataagaga aatgcgagaa ttattccgta agttaaatac agattatgga
     2581 ataactatat ttatttctag tcatattctt tcagaggtag aacaaattgc ggacactatt
     2641 ggaattattc aagatggtaa acttattaaa gaaatttcta tgtcagatat acacaaatat
     2701 caaacagatt atgttgaagt agatgtagat aatgtggaac ttgctggata cttgttagaa
     2761 aaagaatttg gaataaaaga ctttaaaatt acttcggaaa gttgtattga aatatatgat
     2821 ttacgaaaag atgtaaaaga aatatccaaa atatttatca aaaatcaaat tggtataaat
     2881 agcattggac gtaaacaaag ttctttagaa gattacttct tccaaactac aggtacagga
     2941 ggtatagaaa cactatgata catttaatga aactagaatt aaaaaaagtt gggctaaaaa
     3001 gatatttttt attttcaata ctggggattt tgttatgtat gttttttgtc tttactggat
     3061 tgaatgataa atctacttca atatatgatt atgatgttac atttaggaca atcagtttag
     3121 ttttctgttt ttactatatt atattatttg ctgtgttgaa tgtggcatat ataataaatg
     3181 aatatacaaa taaaacaatc ttgattttat tctcttatcc acttgaccgt aaaaaactta
     3241 ttttatcaaa gttacttttg attacgactc ttatgatatc atcaatgata gttggatata
     3301 tctgttgttt tacattcgtt gttgtgttgg ataagtattt taatttagtt attggagatt
     3361 ttcatatttc aattttatct tattggatac caggagcaat taaaagtatt attgtatttt
     3421 gctcattagg tatatggaca ttcgttgttg gaatgataag aaaatcaata cctgttaccc
     3481 ttgtcagttc aattattttt atcaatttaa gacaatttat tttagctggt acaaatacaa
     3541 ctcaagacag tctgatttct gtttttatta tagttggaat aactgtgatt ggtatatatt
     3601 atatactaaa tcataaagtt actgaaattg actagatact gtggatagga aggtagttat
     3661 taattgtatc ttcttgggat aataatgatt tgctattata tcagctatta ttaatattat
     3721 tagagtttta ataatattaa taatagctat atattttttc ttcttattta taaatttaat
     3781 gatttatagt cataaaatga actctaagaa gagataaaaa tgcgttttat atgtttttag
     3841 attaatatga aatatcacaa tgaaatgttg tacaaagtga tatataataa ttatatgaac
     3901 tataaaattg actaaactta ttgactaata aattagatga aaagttgaga cttactgaaa
     3961 ataaatacaa tgaaatatat actacaagta ttaaattaaa tctgaacttt acatactatt
     4021 agaataagta ttataagatt ataatgattt aaaaatatta aaataattga ggtgataaca
     4081 tgaacaattc ctttttagat aaattgattg agacaaaaga acttaaaaat tcactttata
     4141 atgtgttaaa acacaatttt ctttatcatt ctaataagat agagggcagt acttttacta
     4201 ctgaagcatt agcactttta ctcgataaga atgttgttac aggaagacat actttagatg
     4261 atgtacaaga aactgttaat tctagttatg tatttgatac agtaattgac tcactgaaag
     4321 agaaaataac acataatttc ttaaggaatc tacattcaag tttaatcttc aatacaaccc
     4381 tacattccag agggatggct ggtatatata aaactatacc caatatgata ctaggaactg
     4441 atgtaagcat agcacaacca tttgaagttg agccaaagct tgatgaatta attgaatggt
     4501 actatagtca gagtgaagtg tctattaaag ttatagctga atttcattat agatttgaat
     4561 tgatacatcc atttcaagat ggtaatggtc gcataggtag atttgttatg ctaaaacaga
     4621 tgttagaaaa taatcttcct ataaaaattg tatcttggga tagtgaggac ttgtatagaa
     4681 actccttaaa ttcttgtagt ttaggtaatt atgtcccttt aattgaatat ttatcaagtt
     4741 tagaagattt tagagaagta tataaaatgt tatggaaata attgtttgta gcaaaaaaag
     4801 tttttatata aatatatttt taactatgct atttaacgtt gatttcttag ttattcttag
     4861 cttggactat acccactatt ttaactatat aaaatagtgg atatagttta actatctctt
     4921 tataactatt tttatgtatc ttagttgttt cttaatattg ggacagttca taaaactaaa
     4981 agtgattttt aattttatca tttataattt accattacat cagaaaaatg cttatcatta
     5041 gaattttcat aaaaggtacc tattttcttc aattaactaa atcaattcta ttagtcttaa
     5101 tctttcgtat ttcaaattga taatacaaga aaataaaaaa taaaaaattt taaatttttt
     5161 att
//
LOCUS       DAEQJM010000135         5109 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.138, whole genome shotgun sequence.
ACCESSION   DAEQJM010000135 DAEQJM010000000
VERSION     DAEQJM010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5109
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.138"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            137..1060
                     /locus_tag="KRQ43_003575"
     CDS             137..1060
                     /locus_tag="KRQ43_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBH2743909.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESINLTKTKIY
                     SNLRDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDGLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLNKKDEDIYKILSLNLLKIIALGNDNSLKGTKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1035..1862
                     /gene="panB"
                     /locus_tag="KRQ43_003576"
     CDS             1035..1862
                     /gene="panB"
                     /locus_tag="KRQ43_003576"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBH2743910.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGAKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIADMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGVFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            1881..2729
                     /locus_tag="KRQ43_003577"
     CDS             1881..2729
                     /locus_tag="KRQ43_003577"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBH2743911.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNINTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PKNIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            3140..3322
                     /locus_tag="KRQ43_003578"
     CDS             3140..3322
                     /locus_tag="KRQ43_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743912.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            4154..5068
                     /locus_tag="KRQ43_003579"
     CDS             4154..5068
                     /locus_tag="KRQ43_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HBH2743913.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKDITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
BASE COUNT         2018 a          627 c          737 g         1727 t
ORIGIN      
        1 atggtatctt gttataagaa ctatacttta aatgttttta attattttgt cttatgtaac
       61 tcatatcctc aggaatgaga ttagaaatta agatgttgta tcacaaagtg gaggtgatac
      121 tattaaaata ggctttattg gttctggaaa agttggaaca tctttggcaa attatttttt
      181 atcaaaaggt tattgtgttt caggctttta tggaaggaat caattatctt tattagaatc
      241 aataaattta acaaaaacaa agatttacag caatttgaga gatataattt atgaaaacga
      301 tatattattt attacaacat cagatgattc tattgaaatt atagacaaaa aactttccaa
      361 atttaattta aaacataaat acatttgcca cacaagtggc tctttaaaat ctagtatatt
      421 gttctgttca aaaaaagcag gtgcattaat ttattctatc catcctatat ttgcattttc
      481 caataaaaat accaacataa aaaaaatgaa agacatttgt ttttccatag aaggtgataa
      541 tgaacaagat gatttagtta ttcaaaattt catagatggt ttgggaaacc aattttttat
      601 aagagataag gatacttcat ccacttatca tctagctaat gttttagttt caaatttagt
      661 attatcttta ctagatatag gagtaagtta ctttattaaa ttaggtttat ctgaagagga
      721 atctttaaaa gctatcagtc ctttagtaaa aaaaaatata gaaaatatac ttgataatgg
      781 ctttactaaa gctcttactg gtcctgtttc tcgtggagat ataacaccaa taaggaaaca
      841 tctatctgta ttgaataaaa aagatgagga tatctacaaa atactatcct taaacctact
      901 aaaaataatt gccttaggaa atgacaattc attaaaaggt acaaaaaata ttactataga
      961 aaatgcaatc gaaaatttaa taagtaaatc tgaaaaatac aaagaaattt acaaactttt
     1021 aggaggaaaa aacgatgaaa aataccatac agacttttaa gaacgctaaa tatgaaggaa
     1081 aaaaactatc tatgcttact gcttatgact actcaattgc aaaaataatg gatgaatgtg
     1141 atataaatgg tattttaata ggcgattcat taggaatggt cataaaaggt gaagaaaaca
     1201 ctctatctgt tactatagac gaaattatat atcatacaaa agctgtaaaa aatggtgcaa
     1261 aaaatgcctt aatcgtaagt gatatgcctt ttctatctta ccatgtttct atagaagatg
     1321 cagttaaaaa cgctggtaga cttataaaag aaggaggagc tcatgctgta aagttagaag
     1381 gtggctcaaa cgttataaag caaatagaaa gcattgtaaa tgctcagata cctgtaatgg
     1441 ggcatttagg attaactcct caatcagtaa attcatttgg tgggtttaag gttcaaggaa
     1501 ataccagtga aacagcaaga caacttattg aagatgctaa attaatagaa aaagcaggtg
     1561 cattctctat tgtccttgaa ggagttccta cgaaaatagc tgatatggta actaattcta
     1621 tttcaattcc tacaataggt ataggggcag gaattaactg cgatggacaa attttagttt
     1681 atcaagatat gttgggagtg tttggagatt ttgttcctaa gtttgtaaag cagtatgcaa
     1741 atataggaga tataatgaaa gattcaatta aaaattacat cctagaagtt aatacaggtg
     1801 catttccaca agaaaaacac agcttttcaa taaatgaatc tgagttagaa aaattatact
     1861 aatattaagg atggtacaaa atgcttgtaa aagaaattaa attactaaga aatataatca
     1921 aagattggag aaaacatggc tattctatag ggcttgttac aacaatggga tttttacatg
     1981 aaggacacca aagtcttata aaaaaagctg taaaagaaaa tgataaagta gtagtgagtg
     2041 tatttgtaaa tccaactcaa tttggaccaa atgaagattt taatagctat ccaagagata
     2101 tagataaaga ttttaaatat tgtatggata gtggagcaac agtagtcttt aacccatcac
     2161 cagaagaaat gtatttaaaa ggtaattgta ctaccattaa tgtttctgga cttacagatt
     2221 ttctttgtgg agctaaaaga cctgttcatt ttggaggtgt ctgcctagtt gtttcaaagt
     2281 ttctaaatat agtaacacct gataaagctt attttggaga gaaggatgcc caacaattgg
     2341 ctgtaattaa aagaatggtc aaggatttaa acataaatac agaaataata ggctgtccta
     2401 taattcgtga aaatgatgga ttagcaaaaa gttcgagaaa tacatatctc tctgaggaag
     2461 aacgaaaatc tgctctaata ttaaataaga gcttaagttt agcaaaagaa gaattagtaa
     2521 aaggcaatct aaatccaaag aatataaaag aattaataac agctaaaata aattctgaac
     2581 acttagcaaa aatagactat gttgaaattg tagatagtga gacattacaa cctgttaagc
     2641 aaatagaaca ttctatcctt gtggcaattg ctgtgtttat aggaaaaacc agactaattg
     2701 ataattttac atttgagtta aatatatagt atataatttt atataatata tctaaaaaat
     2761 aatagaatac ctaaaaagta ataaattacc taaaaaataa taaattgctt agaaaataat
     2821 agattacaat aactaaaatt ttaaaattaa attccttaaa agtatgatta attataatta
     2881 tataagtata ttcttattac acttatatta atttatatta aatatctact aactcaaata
     2941 ttcataatta aactttaaac tggataaatt ttcttttaag aatgaaagtt tatccagttt
     3001 tgcgattata ataaccagtt ttacatatcc acttgtaaaa tatatctaag caatatatca
     3061 tactatatag atttatgagt gaaataatat ctgctattta ctgaatattt ttatttttcg
     3121 ttttttaggg ggattagttg tgtttaaaga taagattgat gaatgtgttc atataatgac
     3181 tgcatatatt gctagtttaa aagaatacta ttcattcata gaaactcaaa ttggtgattt
     3241 tattaaaaaa tatggagaag atgttgtaga gttatgtctc catagagtga tgattctact
     3301 atgcgaatgt ggtttggcat aaaattaaat ttattaaaat gggtaagaag aatcctatat
     3361 aatattcttc ttacccattt taatatatca atttcatagc ttatcgttta aaatatttta
     3421 cctccattac tagacaactt tacattctct ttttaattct agtatattta aatcatttta
     3481 gttgctcctt atttattctt attacttgtt ttattttata aataaaataa ttctttttaa
     3541 taatgttttt tgttgatatt cctatcacac atccaattat ttatcattgt cttgaaattg
     3601 tttgcatact taatttaatc caattgaaac accccagcat agaatcccct gtaaaataga
     3661 agttggatta aatcctaaca tccatacaga aaatactact ccaagcacaa gcaatataat
     3721 ggaatatatt tatcacttaa ttttttatac tttttaaatc ccatacctaa aacattaagt
     3781 gcagctatta gaattaataa ttgttgtggt ataaaattat gattgcttca tatttattca
     3841 ttttttgcta taaaagttct tgtttcacaa aaaatatttg ttttgtatca aaataatact
     3901 tataaattac ataattctca taaaaatttc tagtattact tgtgctctta ataaataata
     3961 gccaacaagt accttaaatc attatatcta tatctaataa gaaacacagt aagataattt
     4021 tttcgcccat aacttaataa aaactgttga tattagtagc aattgaattt agttaattta
     4081 tttataatat acataaattt aaatattacg aataaagtat tataaatagg atactttcta
     4141 aagggaggaa attatgatag ataatcaaaa atatgttatt ttatcactag aattacattt
     4201 atttttttca agaattatga aagagcatgc tcttttttta gaagcaggat tcacaaataa
     4261 aaattataat cttgctatgg aagctgacca ctataaaaag caatttgaag atttattatc
     4321 atacactgtt agtgctagta atggtataat tagacctgat atattatatt cagaagagct
     4381 tgtaactact ctcacatcag ttgcagaaca aaaaacagaa gagtttacag ggatagaaat
     4441 aaacaaagac atcactacaa gagaattaaa tctacaaagt ggtgtaaacc cacaagttgg
     4501 tcaagactta gtgaactatg tagctcaact taactctgat gcaataagat tacttgatgg
     4561 gcttattaat tttaaagaaa gagtcttaga tggtgtacta tcatgtacta tatttacatc
     4621 aaactaccct ctacttcttg aacatataat acatgaagca aatttatatc gttcttatgt
     4681 agttgacctt gaaaataaaa tagatattga gtcaaaaaac gctaaagaaa tagaattatt
     4741 ctgggaccat attatgatgg aacatgctct gtttatgaga ggattactag acccctcaga
     4801 aggtgaacta ataaatactt caaatgattt tgctataaaa tttaatgaat taattgaaaa
     4861 aacaaacgaa atgactgatt ctaatatcaa gaacattaca gaagaaactc taaatgaaac
     4921 tgttgagttt aaagatttta aagaagcagg agcatcagga atagaacagt gtaagataaa
     4981 atctataata ttaccacttt tagcagacca tgttttaaga gaggcaaatc attatattag
     5041 aatattggag agttataaaa acatgtaatt aaaaattact tttaaaataa tctttgcata
     5101 tttagataa
//
LOCUS       DAEQJM010000136         5093 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.139, whole genome shotgun sequence.
ACCESSION   DAEQJM010000136 DAEQJM010000000
VERSION     DAEQJM010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5093
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.139"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            30..1034
                     /locus_tag="KRQ43_003580"
     CDS             30..1034
                     /locus_tag="KRQ43_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH2743914.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNAALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGIKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1159..2271
                     /locus_tag="KRQ43_003581"
     CDS             1159..2271
                     /locus_tag="KRQ43_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH2743915.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSVPTSAEKDKLNSKSKNEEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2694..3455
                     /locus_tag="KRQ43_003582"
     CDS             2694..3455
                     /locus_tag="KRQ43_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743916.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3458..4276
                     /locus_tag="KRQ43_003583"
     CDS             3458..4276
                     /locus_tag="KRQ43_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HBH2743917.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4456..5058
                     /locus_tag="KRQ43_003584"
     CDS             4456..5058
                     /locus_tag="KRQ43_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HBH2743918.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
BASE COUNT         2130 a          476 c          918 g         1569 t
ORIGIN      
        1 tatcgtaaat gtatgaggag tgaaatttaa tgcgtttcaa aagaatattg atattgatgt
       61 taactgtagc aatgatagct ggaatgttgg ttgggtgtgc taataaccca agcaataatc
      121 ctagctctag caaagataat aaaagtgata taagcgataa aagtaattca aaaaaatctg
      181 tatcaatgat actagatatt gaaggaacaa ataatgaagc tatgaataat gcagctttat
      241 tagcattaaa caatgctcaa aagaaactta atatagatac aaacaaagtg gaatcagatg
      301 attcctcaac tttttctaat agtatagata ttttatgtaa tgacaattac gatttaatta
      361 tagctgtagg agctagattt gcaaaaccat tggagatggt agccaagaaa tatccaaagc
      421 aacaatttgc aattatagac tatgagtatg acaagcaacc ttctaatata acttcaattt
      481 cttatgaaga taataaatct ggatacctag ctggattaat tgctggaaaa atgactgaaa
      541 gcgataaggt tggttttata ggaggaataa agagttctag tagggataaa tttgaatcag
      601 gttttagaga gggtgttaaa ttttctaata gtagtataaa ggatatttca gttgagtatg
      661 cagatgtttt taaagatagc aaatcagtag aatctatagc taaaaaaatg atggataatg
      721 gagtggatat tattttttct actactgaag atgattcaaa agctgtaata gatgcagtaa
      781 gggcaaaaaa taaaaaagtt atagcaacga ataaagacca acatgagtta gctccagaaa
      841 atgttataag ttctattgta aaagattttg agaatcctac ttataatctg atacaaagtt
      901 ttgtaaaagg aaattataaa ggcggaaaag ttatagaaaa cacagttaag tctggaagta
      961 ctgggcttgc ccaaaatagt tctcaaaata ttcctccaga tgtgttagaa tatgttaata
     1021 agaacaataa ataatctact ataatatcca agaatactta tgactttagt tatgaggtga
     1081 attggatgtt ataatagaca tatatagaaa gacgtatgca gaggtaggca gacctatcta
     1141 aatcagggag tgaattttgt gaaaataaaa aggatattga tggcttgctt tgtagtagtt
     1201 tttacaattt ttatattagc tatatgtaac tttgattttg gatttgataa agtaaataag
     1261 aataattcta atatagatag tgctaaatcg aaacagagtg agtctaaaag tgtaccaact
     1321 tcagcagaaa aggataaatt aaatagtaaa agtaagaatg aagaagatga cacagaagat
     1381 gattcatatg taagaaaaac tattggagta ttgttagata ccgaaaactt aaataacgaa
     1441 tcatataata ataatgtact atcagcctta aaaagggctg atgaagattt tgatgttagg
     1501 ataaaacttg aaaaaccaaa gacttctaaa agttttaaag agagtataga aaaactacat
     1561 aagtatgaac cagatttgat aatagcagtt ggagctagat ttgcagagcc aattaaagaa
     1621 gctgctacta aatatcccaa acagcaattt gcaatagttg actatactta taaagttcag
     1681 ccagctaatg taatttctgt atcatttcaa gataatgtta ctggatattt agcagggctt
     1741 attgcaggta aaatgactga tactgggaaa gtcggtttta taggcggagt tgagggttct
     1801 agtagagata agtatgaatc tggatttaga aaggggctta aaacttcaaa taaagatgct
     1861 gagttactag ttaagtattc aaatatattt gaaaaccctg aatcagctag aactattgca
     1921 aaggaaatga gagattctga tagagatgtt gtattttcag ctacagaaga tgatagtaaa
     1981 agagctattc aggtagcaag agaaaatggt ggtaaagtta tagctattaa taaagaccaa
     2041 tacgatatgg ctccagataa tgtaataagt tcaattataa aagatgtaga acaacctgtc
     2101 tatgaactga taaagaacgt tgcaaaagat ggttttaagg gaagtaaagt aatggaattt
     2161 aaaataaaag atggagaact tggcttgact tcaaagagca gtagaaatat accaccagat
     2221 gttttggaat acataaaaaa agagtataac aaagtgaaag atacatatta attattgatg
     2281 tagaagatta taaaaatata ctgtttaagt ttagattagc aataaaaaga tatatttatt
     2341 aaatttgtgc taactgtaca aaatatattg attaagttta gattggtgat aaaaagatat
     2401 atttattaaa tttagtctaa ctgtacaaaa tatattgatt gagtttagat tagcaataaa
     2461 aagatatatt tattaaattt gtgctaactg tacggaatat actgcttaag tttagattag
     2521 tgataaaaag atatatttat taaatttgaa ccaactgtac aaagctatac taattaagct
     2581 tagattaact atataaaatt ataacaataa gtgtgtgggc agaaaaattc tgctacacac
     2641 tttatttata ttcatataaa aaaattatca aaaaaaagaa aaaggagtaa aaaatggaat
     2701 ttacaagaga accatttata ctagatgacg atttgtgtct agctttggtg gacaaaagaa
     2761 ttagttatct aatggaaaat gaattaaaat taagaaatat agagataata aaaacaatag
     2821 aatgtaaaga attatatgaa agcataaaat atcacccgga tatatgtatt tgtaatttag
     2881 gaaaaggaga tataattgtt gcgccgaatg tatataatca atacaaagag ttattaagta
     2941 gatataaatt taatataatt aagggagaag ctaatttatt aaatagatac ccttatgata
     3001 taccttacaa tattgcgata gttggtgact atgctataca caattttaag tatactgaca
     3061 aagcaatatt agattatatt gaaaataata aacttaaaaa gataaatata gagcagggct
     3121 attctaaatg ctcaatctgt atagtagata gaacgtctat aataacatca gataaaggta
     3181 tttggaaaag tatgaagaat acagaaatag agtgtttatt gatagaaaaa ggtcacataa
     3241 atttatttga gatgaattat ggatttatag gtggatgtac agggttgatt tctaaggata
     3301 aactagcttt ttgtggagat gttaaaaaac atcctgacta tgaacgtata aaaagttttg
     3361 tagaaagtaa aaacaaggag atagttacac ttagctgtga aaatttacta gatataggtt
     3421 ctatagttcc tctcatgaca agaaaggagc gataactttg gttgagaagg ataatatttc
     3481 ttccatgaaa tttttgagga ataataatgt aaacgataga ttaatatata cgaatgacat
     3541 tgtagaagta gtgatagatt ctgcaaagca agaagtgtta aataaaaaaa tacttaatgg
     3601 tactaaagct gaacaaagag ctttaaatat tgatgagata tcaacggaaa taactagtat
     3661 gataataagt ataatgaaag agaaactttt gaaagaatac attctaaaat gctatgggcg
     3721 tacatatcct gaagataaaa ataatatata catatattca ctgaacatat ttgctaaaaa
     3781 agagattttt atgagagaaa cagtatttac tagggtgaga aattatatag aagaaaatga
     3841 ttttataaat gtagaaggtt ttattagatt tagaatgaga gaatttatga aatatatttc
     3901 tgctataggt gatattgcag ttgaggagta tttaataaag aaagaccaag atgaatttat
     3961 aagagtttta aaatacttta tagatactca agaagaaaag attgatttgc ttaaagttca
     4021 tataatggaa gataatacat ttgttttata cgataaaaat ggaaataaga tagacagtat
     4081 agatgatgaa gaaattataa atatggtaat aagagaaaat ttaaattatg aggacttttt
     4141 aataagtacc ttattaactc tatgtcccaa aaaaatagaa atattggatt tgttaaataa
     4201 taattgctca aaggaaatta tagatactgt agaagcaatt tttgaaaata aagttagtat
     4261 aattatggaa aactagaatc taagcatata aaagctagcc atataaaatt aaaaaaattc
     4321 tttttaaatc gacacaaaag acttataatt gtatataaag ctatagtata actagagtta
     4381 ttaagtataa agaatatcta cttgattaat gcaatatagc tggcaaatat acaattgata
     4441 aggagtaatt ttataatgga taatttaatt aggatactga tattagctgt tattggtgga
     4501 tttataggtt atgttacgaa tgtagttgct ataagactga tatttagacc aatagagcct
     4561 attaaaatac ctattttaaa tatagaaata gtaggtctta taccaaagag aagagcagaa
     4621 atagcagcaa atgtaggaga aataattcaa gaagaatttc tttctatgga cgaaatactt
     4681 gcaaatatca ttactgacga agataaggaa gaagttgtaa gatacataaa agcaagggta
     4741 aaaattataa tacatgagaa agtttcattt atcccgagtg gtataaaaaa catgatacaa
     4801 gattatctag gagagataat tgagtctgaa gttaagcaaa gtatagatga attgagtaaa
     4861 aatataataa ataaagcaaa tgaacgtata gatatacaaa aaatggtcga agataagatt
     4921 aatgaactag atttatatga attggaagag ataataataa gaatagctaa gaaagaatta
     4981 aaacatatag agtttttggg gcttgtctta gggtttttaa taggtatagc tcaagggtta
     5041 attactatgt ttatttaaat atatgagaag tagcatttat ttaagtacta att
//
LOCUS       DAEQJM010000137         4869 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.140, whole genome shotgun sequence.
ACCESSION   DAEQJM010000137 DAEQJM010000000
VERSION     DAEQJM010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4869
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.140"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(326..2461)
                     /gene="rnr"
                     /locus_tag="KRQ43_003585"
     CDS             complement(326..2461)
                     /gene="rnr"
                     /locus_tag="KRQ43_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBH2743919.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILAKILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3057..3671
                     /locus_tag="KRQ43_003586"
     CDS             3057..3671
                     /locus_tag="KRQ43_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH2743920.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3689..4051
                     /locus_tag="KRQ43_003587"
     CDS             3689..4051
                     /locus_tag="KRQ43_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743921.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYKGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4157..4654
                     /locus_tag="KRQ43_003588"
     CDS             4157..4654
                     /locus_tag="KRQ43_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBH2743922.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1592 a          733 c          599 g         1945 t
ORIGIN      
        1 catttcttaa ttacttattt ttcaattagt cacttccatt aaacatttct taattattta
       61 tttttcagtt ggctttttct attaaatgtt tcttaattac ttatctttca gttagctctt
      121 tctattaaat atttctcaat tacttatttt tcaattagct actttcatta aatatttctt
      181 aattatttat ctttaagtta actatttcca ttagatattt cttaattacc tatttttatc
      241 atttatttta tagagtattg tgcactatat atttatacat atcataaata ctacaacttg
      301 ttatctctta ttttagctgt tttatctact cctctatttt ttcaactatc tcaaagtcaa
      361 tttctttaaa atctacatta acactttcaa cctttatctt aacaaggtct cctatcttat
      421 atgacttctt agttctttct cctaaaacac tataagaact ctcatcataa atatagtaat
      481 catcattcat atttgcaagt cttatcaatc cttctatagt attatctaac tcaacaaata
      541 ttccaaatga agttacgcta gatacaacac cctcaaattc ttgaccaact ttatccttca
      601 tataaagagc cttatagaaa tcatgtacat ctctttcagc taactctgcc tttctttctt
      661 tctcggatga ttgaacagat gcataatcca ctatagtagt aagctgttct tgtctttttc
      721 cacttatttt attatttaaa gattctttta ttattctatg aatttgaagg tcaggatatc
      781 ttcttattgg tgaagtaaag tgacagtaga atttagctgc taatccaaaa tgtccactac
      841 attctggtga gtacttagct tgttttaaag aacgaagcat tatagtactg atagctcctt
      901 cttctttttt gccctttatt ttctctatta taccttgtaa tgcttttgga tgtacttcct
      961 ctttatcacc ttttattata tatccaaatg tagatataaa cttactcaat tcttccattt
     1021 tttccaaaga tggtgtctca tgtattctat acacaaacgg tattcccatc cagtaaaaat
     1081 gttcggcaat tgtctcatta cttataagca taaattcttc tattatctta ttagatattc
     1141 ttctttcata tggctttata tctacaactt cgccttttcc atttagaatt atctttgcct
     1201 ctgggaaatt gaagtctata gctcctcttt tttctcttct tgacataaga atcttagcta
     1261 aaatttcagc atttttaaaa tcttcaacaa catgttcaaa agtcttttta agtttttcat
     1321 catccttttc taatatatca gatacttctg tataagtcat tctagctttt gaatttatta
     1381 cagattcaca tatttcatgt ttaaccacat ttcctttatg gtctatttcc ataaatatag
     1441 aaagagttaa cttatcttca aatggattta agctacatac tccatttgaa agagtttttg
     1501 gcaacattgg aattacttta tctactaaat aaactgatgt agctcttttt aaggcttcct
     1561 tatcaagttt atttttctct cttacataat gtgtaacatc agctatgtga actcctagtt
     1621 tgaagtttcc attaggtaat acttctattg atatggcatc atctaagtct tttgcgtcat
     1681 ctccatctat agtaaatatg tttaaatctc ttaaatctct tcttcttttt atctcttctt
     1741 gaggaatctc aacagctaca gcttctgctt cttgcaatac tttctttgga aattcttctg
     1801 gaagaccatg ttctcttatt atagaatcta tttctacgcc tctttcacct ttttgaccta
     1861 gtatctctat aattttgcct tctggttttc tatcctcttg tggccatact gtaatttcac
     1921 atactacctt atcattatct actgctccac taaaatgttt tttaggtata tatatatctt
     1981 tagtaaattt cttgttgtct ggtgttacaa atccaaaagt tttacttgat tggaaagtac
     2041 ctactattct agttatttct ctctttatta cttttactat tcttccttct gctctctttt
     2101 cttcagttgc aggtactact atttctgcca taactctatc gttatgcata gcaccattta
     2161 tattgtcact tgagataaat aaatcctgtg tatattcaac atcagattct acaaatccaa
     2221 aacccttttt gtgtgataca aattttccaa caaagtatcc catttgattg ggagatacta
     2281 tttttccttt tttagtaaag cagatataac catcttcttc taattcattt aaaaaattat
     2341 aaaacattgg catttctgat gaatgtatat caaatatttc tgctaattct tcttttttta
     2401 gaggattata tgcactttca tttattaatc ctagcaaact ttctttaagt cctggtatca
     2461 tttttccctc ctgttttact tttcattata ttattattta tattgtcttt tatatttctt
     2521 cagataaaac attttttact tatcacataa ttttctatat tttcttatta ttattacaag
     2581 ttaaaattac ttatttatat ttttgattta atgtaagctt tgtcatacta acttcaaaca
     2641 aattatgatg ttttataaat tatttgtaaa tatcattata attacttaag ttattcttta
     2701 tcataattgc ttaaattact ctttatctca taattataca ccatcaaata ggattggtaa
     2761 aatattcatc tcatataagt attactatat aataatttat tctattagta tactcaaatc
     2821 atgtaaaatt tatataactc aattaatttt ttaaatacaa ctttataata taaaacttat
     2881 aataaaagta aatttatatg ttaaatgagg ttgatttttt attatttttt atttatgcta
     2941 gtactaaaga cttgcaaacg ttttttgaca agtctttatt ttgtctaaat taaacaaact
     3001 tttttacaaa taaatacata aaatttaaac taatctattt attggaggag ataaaattgg
     3061 aagaagtaat tgcaaaaatt attactatag aaaatggatt caaagaaatt gaaaacattg
     3121 ctaaaaaaat tgtaaaaaat aatgactcaa aaaagtgtta ttatctatca atctacttat
     3181 ataggtcaga atattatcaa gtaagagaat tggctgtgtt tatacttggt tttatatcag
     3241 taactatttc tgaagctttg ttatttttaa aagacaatgt gagtaaagat gaaaactgga
     3301 gagtacaaga aatactagct aaatcatttg attattattg cagtgaagta ggatatgaaa
     3361 aggcacttcc tgttataaaa gaatggctta attctgatag tccaaacata aaaagggctg
     3421 tgacagaagg tcttagaatt tggactagta gagactattt taaatctaat cctgacgttg
     3481 ctatatcact actttctagt ttaaaagaag atgatagcga atacttgaga aagtctgtag
     3541 gtaatgctct tagagatata agtaaaaaat atccagattt agtaaaaaaa gaattagatt
     3601 catgggatat atcaaataaa aaagttgagt ttgtatataa gcttgcttca aaatgtatct
     3661 tggcaaagta aaatggaggt gaacttattt gaaacttcgt gatgagtata cttgcccatt
     3721 agaactaaca catgatatga taaaaggcaa atggaaatct attatattat ggagattacg
     3781 cataggacca acctccttat caaaacttga aaaggaaatc aatggtatta atcaaaagat
     3841 gttacttgaa caacttaaag aattaattga atttggtctt gtagataaaa agacatataa
     3901 aggttaccca cttaaagttg aatactcact tacacctatt cgagggaaac aaatattgga
     3961 tgctttggct ataatgcaag atataggaat tagctttatg ttggataatg gtatggaaga
     4021 tattcttaag gaaaaaggtg ttttaaaata aatagatacc cacaaaaaag taagtaattt
     4081 accattattt tcaactggta tataattaaa ttatagatat attctattaa tttattataa
     4141 taggaggtaa attattatga aagtaactag tacaggtata gtaaatggtg ttatagaaga
     4201 taaatacggt aaaagaggaa ctcagttcaa tgaaggtggt atgcctacat attcactacc
     4261 tctaaagttt gaagatgctc caaagaatac agtatccttt gctgtatttt tagaagataa
     4321 agactctgtt cctgtatgtg ggtttgcatg gatacattgg ttagctgtaa atataacaaa
     4381 agatgagtta aatgaaaatg aaagtgtaac agctactgat tttgtacaag ggactactag
     4441 ttggcatggc aaactaggag gtcttgacag attagaggcc agtgtatatg gtggaatggc
     4501 tcctccagac agacctcatg tctatgaaat acatgtattt gcacttgata ctatccttga
     4561 ccttgaaaaa ggattctata tgaatgaatt tttcaaagct attgaagggc atgttttaga
     4621 tacatttaca ctaaaaggaa gctattctaa ttaattaggt ttactatagc taatcattaa
     4681 ttaaatgcta catttaattg atgattagct taattgttat tagaatattt tctgcacttt
     4741 atcttaatat atattttagt tgactggtat tttaatttct attagattat tatcaattta
     4801 tataaattga ttttagctta aaacttactt atctatttca gtttctatta gaattattat
     4861 tagactcat
//
LOCUS       DAEQJM010000138         4854 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.141, whole genome shotgun sequence.
ACCESSION   DAEQJM010000138 DAEQJM010000000
VERSION     DAEQJM010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4854
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.141"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(59..544)
                     /locus_tag="KRQ43_003589"
     CDS             complement(59..544)
                     /locus_tag="KRQ43_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH2743923.1"
                     /translation="MISELMLKNFGKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     regulatory      complement(627..720)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(1076..1459)
                     /locus_tag="KRQ43_003590"
                     /pseudo
     CDS             complement(1076..1459)
                     /locus_tag="KRQ43_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      1686..1783
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1838..2014
                     /locus_tag="KRQ43_003591"
     CDS             1838..2014
                     /locus_tag="KRQ43_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743924.1"
                     /translation="MFGNKMDKCTHVLTAYISGSYDYCNFLDTQLDDFILEYGESVVE
                     SCLHQVMVLVSKYN"
     gene            2240..2440
                     /locus_tag="KRQ43_003592"
     CDS             2240..2440
                     /locus_tag="KRQ43_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH2743925.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            complement(2604..2903)
                     /locus_tag="KRQ43_003593"
     CDS             complement(2604..2903)
                     /locus_tag="KRQ43_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743926.1"
                     /translation="MGFYINYVVCKVKILFSSFSKIILFYINYVVCKLFITLKAILLK
                     TQIIVTTHSPHILQIDSKEEMIVLDMAESGNVYKKELELGEYGVLGWTNEGLYLH"
     gene            3125..3307
                     /locus_tag="KRQ43_003594"
     CDS             3125..3307
                     /locus_tag="KRQ43_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBH2743927.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIVF"
     gene            3378..4223
                     /locus_tag="KRQ43_003595"
     CDS             3378..4223
                     /locus_tag="KRQ43_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743928.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINNSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(4447..4611)
                     /locus_tag="KRQ43_003596"
     CDS             complement(4447..4611)
                     /locus_tag="KRQ43_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743929.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
BASE COUNT         1791 a          627 c          533 g         1903 t
ORIGIN      
        1 cattaatggg attctttttt gtgatttatt aacatattta aagctcacta gtatcgtatt
       61 ataaacttaa atgctcttct atgtattgat tatatacata tccagaatat cgtttttcat
      121 ttttattgat attaactctt gcccattttc caacgctata acatacttca actttaaaac
      181 catcagggat tgtagttata actttagatt ctaatgttct atcatttcta agttctaaac
      241 ttaatccatt tgttcttata tttcctatgt aattcttttt tctatttttt attgtatcat
      301 tactattgtt tttagcatta cttaatcttt ctaaatattt ataaagtaac cagcctttgt
      361 cataattact ctcaacttct gcccatattc catctacaca ttttaactta acaattttac
      421 cttctggtat actttttaat ttcaaactat ttatgtctgg tttttctctt aaattcaatt
      481 taattttagt tttaaaattg atgctagatt tgccaaaatt ttttaacatt aattcagata
      541 tcatcttaag ccctcctctt gccaaatatt aagttattaa aatatataac tctaaaaata
      601 cttttaacaa aaagaattat tatctttttg gcaactggct gacatgacct ttattacata
      661 aagattttag tccctatagt tttgcgtcat tagatttatc taatattgcc tatatctgaa
      721 taataacata atttgaacaa ttaaaaaata atattacctc aaattttata ttatttaaat
      781 ataaattaaa tttttaatta ataataatca aaaaatatct ttatatttat tcaattactg
      841 ttctttatag tcaatataaa agacagtaat ttatctatag tgttacttat attttatata
      901 tatggctatt tttcaacatt ttacaatata tataacattt atttttttaa cttttgtcag
      961 taaaatgtca gcaagacact ttatccacaa tttttatata agttttccac aacttatccc
     1021 cagtattatc cacataaaaa aggtagctct tatattatta gctacctttt atttattaat
     1081 cttcatattt ccagcttttt atccaacttc ctatttctat tattttttct tcagttattt
     1141 cttctccatc atgtaatttt gaaattaatt ctgataaagg attgttatgt aaacctctaa
     1201 aaactctttt tccctctatt ttgagatatt ctctctcttt tattaatact gtatagtgta
     1261 catgcctccc aattctctat gatattaaaa aacctttttt ggttaatcta gctaaaagta
     1321 taattgtagt tgtatgcttc caaccatatg ttttttctat ttcatctgca acatcttttg
     1381 atattacagt tttataacca gtattccata tgcatttcat aatttttaat tctgtatctg
     1441 gtaatttttt atttagcata atatattcct tctttcaatt tatgtcactt cttcaaattt
     1501 atctagctta aattataata ggagtttttt agaacaaaaa ctatagttaa tttttaccag
     1561 gtactctacg tgtttagtct gttttttaag tgtaaaataa tgttcatatc tataaattta
     1621 tttaactttc aaacaatcct gttgaataat aactaattct attgtattat tttagttgta
     1681 gaataaaact aaatcggcaa aactagagaa atttagtgac gcaaagctat agggactaag
     1741 acttatataa atatcttatg agttatgtca gccagttgcc aaagagatag tgttcttttt
     1801 gtttttatga aagtttttta gggggataat aatttatatg tttggaaata aaatggataa
     1861 atgtacacat gtattgactg cttatattag cggttcgtat gattattgta attttttaga
     1921 tacacaatta gatgatttta tattagagta cggagaaagt gtagtagagt cttgtttgca
     1981 ccaagtgatg gtattggtaa gtaagtataa ttagatagac attgatttct agagaaccct
     2041 ttttagtttt atctacattt atattaatat atagcaatgt aaaacgctta aatatatttt
     2101 taatattaag aataactaaa atgttgacta aaaaatataa ttaagtagac atttctatta
     2161 atctatgata caatagtatt tgtggtaata cacaattaaa tcaagtatat cttgatatag
     2221 gttaatagga gtatttttaa tgaataatgg aatagtgaaa tggtttaata atgaaaaagg
     2281 attcggtttt atatcaatgg aaggtagaga tgatgtgttt gctcatttct cagctataca
     2341 aacttcagga tttaaatcat tagaagaagg tcaacaagta agctttgata tagttaaagg
     2401 tgctagaggt cctcaagcag aaaatataac tatattataa tatatagatt tttcgggaaa
     2461 gactcttttt agagtctttt tttattgtta gtatatgtaa gataatcatt ggtgaagtaa
     2521 ataaggtata ttgagtaatg ttcttgatag tttatatgct aatgaatttc aaaaaaataa
     2581 gcactcctat aaaaagagtg ctcttaatgt aaatataagc cttcattggt ccagcctaat
     2641 accccgtatt ctccaagttc taactctttt ttatatacat taccactttc agccatatct
     2701 aacacaatca tttcttcttt agaatcaatt tgtaaaatat gaggactgtg tgttgtgaca
     2761 attatttgtg tttttaggag aattgctttt aatgtaataa aaagtttaca tacaacatag
     2821 ttaatataaa acaaaattat ttttgagaat gagctaaata aaatcttaac tttacatacc
     2881 acatagttga tataaaaccc caaaataaac ttagcatctc caatgtttac acatatacaa
     2941 tgctcttaaa attgcagtga acatgcaata gtgcaattga taatacttat catatattct
     3001 caatacctta tatttcaact gctaaacctc aatttgtcac aaatatcgct cactgcaaaa
     3061 tttctatatt tttattatat catagcatat aattaatatt ttcaattaat ttttacattt
     3121 aattatgttt aaattctata ataatgcaac tttaatgttt ctttctggaa ctaatataaa
     3181 aactatttca gaaagattag gtcatgcaga tataaaaata actatgaata gctactctca
     3241 gtttttagaa gagatggaca gagaagcatt tgaaaatttg agcaaaatac tatttattgt
     3301 attttaaaga agatgactta ttcaatattt gatgctagaa tataattaat aaaaatttaa
     3361 ttataggtga ttgtattatg aacattatta aaagcataac tttactctta acattattaa
     3421 ttgtgatatt aatgacagga tgttccccaa gagaaagtgc tagtgaagtt gcaaaaaaat
     3481 atattgataa gatgaactct ggtgactatg aaacagcata tagtttatta agtaaagata
     3541 gtaaaaaaaa aattagtata gaaaatcttg aagaatttca aaatatttta gttagtacaa
     3601 aaagaataat tagttataaa ataggtaaag aaaaaatcat aaaaaaatat aaacatgatg
     3661 gaaaagaata taaaaatgtt gttaaattag aagaaacttt taatataaaa aaccttcttt
     3721 ataaaaaaga tgattctcta aaagtaaata gatattttgt agttgaaaat aacaaataca
     3781 agctattatt gtatgaaagt ttcaaaaaag aatttggtat taatagtatg gaccttgctc
     3841 aacttaagct taatgatttt ggactaaaat actttaaaga agttgacctt atactaaaaa
     3901 aagctattgc tattaatcct actgattcaa agctttatta tgcccaagca tgtaattata
     3961 tgaattttga tggatttcct ggttattcag atacaacata taatgcttta gattcaatta
     4021 ataattcttt aaagtattta gataaaaatg attctgacta caaaaaaaat gcaagtaata
     4081 tatataactt aaaaggagtt attcttatgt ttcacaaaag atttgatgaa gcacaacaat
     4141 atttaaataa agccttatac tttaacaaag ataatgaaga cccaaaatat aatctaaata
     4201 caataaaaaa acatctaaac tagatattta atttttgaat ttataaaata tttttttatg
     4261 tataattcag cactgaatca taatctctac taaactaatt acaagtttaa attataaaga
     4321 cttatttcta tataaatatt actctataac aataagtttc ttatttaaat tttaaaatat
     4381 tatctaaaaa tcataaaaaa gaaggtataa agagctaccc tcaagctcaa tataccttat
     4441 aaatatctaa acttcatttt ttactaattt ttctatatct ttgataatat gttctttaga
     4501 tttttttcca gctatggcat caaaaattgc aacagccttt ttctctccaa acttttctgc
     4561 tacatcatta aagtctaaaa atctaacact ttcttttggt ttaccaaaca tataacacct
     4621 ctcatacatt tttatatatt tattataact tctatagact tatttttcac caataaacgt
     4681 tagacaaatt agtcccttta tttttttaaa ctagctttac cttcaaaatt cttaacaaaa
     4741 acagtttatt ctactctata aataaaaata gacaatttaa tttgtaggaa actgataata
     4801 gaatacagta aataaaactt tgtttaatct atctgaaaaa gttatctatt aaaa
//
LOCUS       DAEQJM010000139         4681 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.142, whole genome shotgun sequence.
ACCESSION   DAEQJM010000139 DAEQJM010000000
VERSION     DAEQJM010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4681
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.142"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            27..688
                     /locus_tag="KRQ43_003597"
                     /pseudo
     CDS             27..688
                     /locus_tag="KRQ43_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            complement(907..1944)
                     /locus_tag="KRQ43_003598"
     CDS             complement(907..1944)
                     /locus_tag="KRQ43_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBH2743930.1"
                     /translation="MNKKLIKAKIFIWSILAISLSIVFISLLIGTIISHSFNFPFNTL
                     NPKYNYDNYIVAKNESFSDKINDINVDWISGEVRIKRSDSNKIKLIQKIPSNFSKKKL
                     AKIMVDGNSLSIYDNSTKKFFIGINLPKPTILELYLPNKLYDKITLYTTSADIYSTYI
                     RSNTVEANTISGAIGLSGNINKINLDTTSGHIDITKLNSKNATLKSTSGEIQLSGKID
                     VLNLETTNGNINLKDIYNKNLTCSSVSGKMNLSGVFSDIKAESTSSNIKINSSKMLSS
                     LYCETTSANVDLSIPDNPGFTLNFDKVSGVLDSDFELNRHSDLYTYKNGITNLYLSTT
                     NGNLTIIKNNH"
     gene            complement(1937..2623)
                     /locus_tag="KRQ43_003599"
     CDS             complement(1937..2623)
                     /locus_tag="KRQ43_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743931.1"
                     /translation="MLDKIRTYIDSSFTGVNETKKVKELKDELFENLKEKYNDQIQDG
                     KTEQEAYNSVISGIGDLSELIESVKEPYSLPSELIEEKKKRALRASIAVALFIISPFL
                     FVVSVVSFGIEPTIAILLMLILIALGVGLLVYNQMTRTNYALYNDNLSNKFKEFEDFE
                     ENYNHINPVYKSFMNAYWIIVVSIYLITSILFNIWSFSWILFIIGAAGVNIVKGIIQL
                     KGYKEEDKYE"
     gene            complement(2635..2955)
                     /locus_tag="KRQ43_003600"
     CDS             complement(2635..2955)
                     /locus_tag="KRQ43_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743932.1"
                     /translation="MIIASDMIRGHTETIILKHLLEKDSYGYEINKSILEKTKGLYEL
                     KEATLYTAFRRLEQSGAITSYWGDEVTGARRKYYSITNIGKEKYIKSREEWNNTKALI
                     DILI"
     gene            3316..4656
                     /locus_tag="KRQ43_003601"
     CDS             3316..4656
                     /locus_tag="KRQ43_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH2743933.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLFLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT         1719 a          516 c          692 g         1754 t
ORIGIN      
        1 tgtgacttta gtcatgggag gttcagattt tggctgaaga tgaagaaaat aatcatataa
       61 atattgagat gcaaagagct tttgagaacg attatttgga aagagctgaa tattatctta
      121 gtcgtgtaca tggtagaaag ttagaagaag gtaaagagta taaagaaatt ggaaaaacta
      181 ttggaataca tatactaaat catgtaaaat ataatcacat agaagattat gtaaattgcc
      241 tgagattaac aatggacgag catccagata tttattctag taaaactgca ttatatttta
      301 tagagcttcc aaaaattcat aaatctgact atatagtaaa tagaattatg ctatggggaa
      361 aacttattga taatccttct agctcagatg taagagttat agctaagaat gattctatta
      421 ttaaaaaagc acttgataga ttaaaagaat taggtagcaa tgaagaatat ttattaaatc
      481 tgaaaagagg tgcttatatc atgaataaaa gtagaaattt taaagaagag attgaaagag
      541 agacagcaat tagagttgca aaagaaaaag attataaaat aattataatg ttgaaaaaaa
      601 tggttttaaa ttagatgaca tattgaataa atttaatgat tttgacttaa gtgaagatga
      661 gataaaagaa gtatatgaaa ataattgatg ataaataaaa agtgaactta tataagtttg
      721 ctgaatctga gcctggaaat atttatgtgt attttttaat gaataaaaat ttattttaaa
      781 aacaataatt agaggtacag ttaattatat ttttatgata ctgtacttct agttttttct
      841 attgtagatt tattatttac taataaatct acaatagaag tgcttttgtt gtaagaatca
      901 ttttatctaa tgattgtttt ttataatagt taaatttcca tttgtagtgc ttaaatataa
      961 atttgtaata ccatttttat aagtgtataa atcactatga cgattcaact caaagtcact
     1021 gtccaaaaca ccagaaacct tatcaaaatt taaagtgaaa cctggattat caggaataga
     1081 caaatcgaca ttggcagaag tagtttcaca gtacagagaa gacaacattt tgctagaatt
     1141 gatttttata ttactgctag ttgactcagc tttaatgtca gaaaaaactc cagataagtt
     1201 catttttcca gaaactgaac tacaagtaag atttttattg tatatatctt ttaaatttat
     1261 attgccatta gttgtttcta agtttaaaac atcaattttc ccagaaagct gtatttcacc
     1321 agatgttgat ttgagtgtag catttttact atttagtttt gttatatcaa tgtgaccact
     1381 agttgtgtct aaatttattt tattaatatt accagagaga cctattgcac ctgaaattgt
     1441 gttagcttca actgtattac ttcttatgta agtgctatat atatctgctg aagtagtata
     1501 taaggttatt ttatcataaa gcttattggg caaatatagt tcaagtattg ttggttttgg
     1561 aagattaatt ccaatgaaga attttttagt tgaattatca tatatagaaa gagaatttcc
     1621 gtcaaccatt atttttgcta gttttttctt tgagaaatta ctagggattt tttgaattaa
     1681 tttgatttta ttagaatcac ttctcttaat tctaacttca cctgaaatcc aatcaacatt
     1741 aatgtcattt attttatctg aaaaactttc atttttagcc actatatagt tatcataatt
     1801 gtatttagga ttaagagtat taaaagggaa attaaaagaa tgtgaaatta tagttcctat
     1861 aaggagtgag ataaatacaa tagaaagtga tattgccagg atactccaga tgaaaatctt
     1921 tgcctttata agctttttat tcatatttat cctcctcctt gtagcctttt agttgtataa
     1981 ttcctttgac aatgttgaca ccagcagcac ctattataaa tagtatccac gaaaaggacc
     2041 aaatattaaa tagtatgctt gtgattagat atatagaaac tactataatc caatatgcat
     2101 tcataaatga tttataaact ggatttatat gattataatt ttcctcaaaa tcctcaaatt
     2161 ctttgaattt atttgataaa ttatcattgt atagagcata gtttgtcctt gtcatttgat
     2221 tatagactaa taaacctact ccaagtgcta ttaatatgag cattaaaaga atagctatag
     2281 ttggttctat gccaaaactt acaactgaga ctacaaatag gaaagggctt attataaaaa
     2341 gagcaactgc tattgatgct cttaaggctc ttttcttttt ttcttcaatt aattcagaag
     2401 gtagagaata tggttcctta acactttcaa ttaactcaga taaatcacca attcctgaga
     2461 ttactgagtt atatgcttct tgttctgttt taccatcttg tatttggtcg ttatactttt
     2521 cttttagatt ttcaaataat tcatctttaa gttctttgac tttttttgtc tcattaactc
     2581 ctgtaaagct actgtcaata taagtacgta ttttgtctaa catattttca cctcctaaat
     2641 taatatatct atcaatgctt ttgtattatt ccattcttca cggcttttta tatatttctc
     2701 tttacctatg tttgttattg aataatactt tcttctagct ccagtaactt catcacccca
     2761 ataagaggtt attgcaccag attgttcaag tctacgaaat gctgtataca aagtagcttc
     2821 tttcaactca tacaatcctt tggttttttc aagtatagat ttattaatct cataaccata
     2881 actgtctttt tcaagtaaat gttttaagat aattgtttct gtatgacctc ttatcatgtc
     2941 agatgcgatt atcatgaaaa tcacctccaa ttaaatatat aatactttga tatacttcgc
     3001 ctgtcaaggt atatcatgag aaaagacatt ttattgtaat atttataagg ttttatatag
     3061 aaataatgta aaaactttat aaataatata ttttatacct agttatagat aactttatat
     3121 agttattatt aaaaaaagca ataaaaagtt taattcaatt tagcaaattt agtgatataa
     3181 ttaaaaaaga aaagaaatat ggacttattt ggaataattt tgacaatcta tttactacac
     3241 gtgtagagtc gtatataatt aaattataca taaaatataa aaaaataatt tagtaatacg
     3301 ttaggagaaa gtattatgat aaagtcaagc ttattttgga atattttcat tgcgatatcc
     3361 tttatgatag aatggtttct ttgtaagaaa atgctagatt atacaagtga gaaaaggatt
     3421 tctaacaaaa aaataaactt ttgtatggta ggtattattg tttttgctga cataatatat
     3481 ttttttgatg tacctccaaa tataagagta attatatcta tgataattac tattgcattt
     3541 tataaaatct catatgatgt gggatttata aagtctgtat taatatcctt aatttattgg
     3601 atgttactaa tcgccacaga tgctttgagt atatctttaa cagtttggct taattctata
     3661 aatgacatga gtagtatggg gacgggagat atatacagaa ttgagtctat aatattggga
     3721 aagatacttt tgattgtgtc tttgttttta tatagagcct taaagataaa acttaatata
     3781 gaaataaata aaaggacatt attttatata gttattccta tagtcgctaa tatagcatct
     3841 ttttttgtaa tttttgaata catatttaat ccagggtctg gtagcttaat acataatttc
     3901 caattcgtta tgatttctgt tgtattgctt atatcaagta tcactttagt tttaattgct
     3961 aaaaaattac agcaatataa tactttagtt gtagaaaaca atatgattaa aaatactttg
     4021 aagtatgaaa atgagtatta tgaagatata gaaaagaaat atttaaaaac tagattacta
     4081 agtcatgata tgaaaaatca catactgtgt ataaatgcta tgattaaaaa aggtattgat
     4141 gttacttctt atttaaataa tttgcaggta gaaattcaga gtaatgactt gttatttaat
     4201 actggtaatt ttatattaga tgctatatta agtgaaaaga aagaagtttg tgataagaat
     4261 gatatagaac taaaaatagg aataaatttt agttgttgtg aagctgttga attagtagat
     4321 atatgtcata tattttcaaa tattttagac aatgcaattg aggcatgtaa taaaattgat
     4381 agtggaaata gagttatttg tgttaaaggt gatgttatgc aaaattttta tttaataaga
     4441 gttgaaaata ctaagatgaa taagattatt actaaaaatg gagatatttt gacagacaaa
     4501 aaaggttctc ttcatggact tggaataaaa agtgtaaaaa actctgtaaa taagtatggt
     4561 ggtaatgttg taattgaata tgatgataaa aaatttgtag ttaaaattgc tattccactt
     4621 agaaatgtga agaaagcagt taatcatgtg atttaaatgt atataaattt gatgtgtaga
     4681 a
//
LOCUS       DAEQJM010000140         4496 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.143, whole genome shotgun sequence.
ACCESSION   DAEQJM010000140 DAEQJM010000000
VERSION     DAEQJM010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4496
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.143"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            60..728
                     /locus_tag="KRQ43_003602"
     CDS             60..728
                     /locus_tag="KRQ43_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743934.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWENDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            887..1393
                     /locus_tag="KRQ43_003603"
     CDS             887..1393
                     /locus_tag="KRQ43_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBH2743935.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1521..2537
                     /locus_tag="KRQ43_003604"
     CDS             1521..2537
                     /locus_tag="KRQ43_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH2743936.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2891..3595
                     /locus_tag="KRQ43_003605"
     CDS             2891..3595
                     /locus_tag="KRQ43_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HBH2743937.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVIICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            3890..4369
                     /locus_tag="KRQ43_003606"
     CDS             3890..4369
                     /locus_tag="KRQ43_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH2743938.1"
                     /translation="MPNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTISGILMFILGVSYFIIIKSLIEVLSSSEHSLFVKDNVKRFRIIGYLLLLNSIMEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         1893 a          376 c          760 g         1467 t
ORIGIN      
        1 taataaaaat atatattata ttaggtattt taaataaatt ttttaaaggg tgatttttta
       61 tggaaaatat aactagttat tttacaacaa tactatgtgt atttatatgc ttatcatctg
      121 tatttatatt tactcaacta gctagagtat ttattaataa gaagaagatt aatcaaaaaa
      181 ttaaatcaag aaacggattt aggtatgata gagattttat tgaagccaga agagaagaaa
      241 tacatataaa ggataacaat aataataaaa ataagagtaa caataagaaa ttaaaggaag
      301 aaaaagtatt taaatacgat aatggtgatt tatataaagg tgagtttgtt gatggaaaga
      361 aaaatggatt tggaatatat attttttcaa gtaaggaaaa gtatgaagga ttatggaaag
      421 atgacaagat gcatggaata ggaaaatata cttatagaga tggttcaata tatacaggtg
      481 aatttaaata cggattaaaa aatggtttgg gaaaattaac atatcccaat aatgacattt
      541 ataagggata ttttttagat aataagaaaa atggtaaggg tgtattatat aaaaatgatg
      601 gaaataaaca agcaggaata tgggaaaatg atgaacaatg taaaagttta gattttaaag
      661 atttaaataa taataaaata aataatgttt atcaaaatag attaaataac aataaattaa
      721 aagtttaatt attctaataa aaaaatcttt atttatgatg gaatatagga tatatctatg
      781 ttgtaatttg taaaatcttc ctatatcata taaaattaag tattgattag tctattacat
      841 aaatatagaa tataaatata tccatttaat aataaggaga agagatatga aagaatatgt
      901 agttgtggat ttagaaacta caggattaga tccatataaa ggttgtgaaa taatagaaat
      961 aggaataaca gaaataaaaa atgaacaaat tgtaaaaaac tattcaaggt tgataaaacc
     1021 taaggggata atttcttcat ttataacaga attgacacat ataagtaatg aaatggtaga
     1081 aaatgaagaa ccactagaat tagttttacc tagatttaga aaatacatag gtgatagaac
     1141 tataattgca cacaatgcga aatttgattt aaaattttta aattactatc ttaggatgtt
     1201 agatttagaa ccaataaaca attatatatg tacagtagaa ttattaaaaa aatgtaaaag
     1261 ttataaagga aaaaacaaga aacttgaaac agcttgtgct tattacaaca tagagaatat
     1321 aaatgctcat agagctgaca gtgatacatt agcaactgca aaactatttt tgaaaataaa
     1381 agatgaatat taattataaa tatagagaaa attagtgaaa atatccttta taaaattgac
     1441 ccttaagctt acaattttgt tctttgattt attttgtaga acaatgtata atgtacctta
     1501 tatgaagaag ggagactaaa atgggttatt acaatgataa tgataataat aaaataagac
     1561 gtaaaaaaat tagtaacaac aaagatagta ataaaaaatc taaacattct tatacttcgg
     1621 caaataaaaa aaataaaagt cctaatacaa gttccagtaa aagaatgagt gaaaaagtag
     1681 attcacagaa tcttataaaa agagatagag atagttttac aagagataat gtaagacctt
     1741 taaatacaga ttacaatcaa agagaaagaa gaagagtcga gtataaacaa agagagaaaa
     1801 aattaaaaag taaaaaaaga aaaaaacaaa aaaggattag aatagttagg gcattattat
     1861 ctattatgtt agttgcacta attatatttt cagtggcagg tgcaatattt acagtttcag
     1921 ctataaaagg gtcaccagaa gttactaaaa agttaattag gtctaaatat ataagtagtg
     1981 aggttgtaag tataaaacaa atgccaaatg atttaaaaca tgcaatagtt tccatagaag
     2041 atgagagatt ttataagcat aaaggagtag atgttatttc tctagttagg tcagtattaa
     2101 acaatgtgtt tacagataca acacaaggtg caagtactat agatatgcaa gtttcaaaaa
     2161 acctgcttac tagtaatgat aaaactatga agcggaaaat aagggatatg tataatgcta
     2221 agcagatgaa taagattatg actaaggatg aaattcttga ggcatattta aataatatgt
     2281 atctaggtaa aaatgcatat ggagctgcaa agggagctga agtctacttt ggtaaaaaag
     2341 ttagtgaatt aaatttagct gagtgtgcta tgttagctgg tatgacaaat aatcctgcaa
     2401 ggtatattga ccatggagag gctaagaaga gacaagtgat tgtactgtat aagatgcatc
     2461 agcttggtta tataactgat aaggagtata gaatagcaaa agctgatgac actccattta
     2521 aatcagaaat tgattaaaat tgtaagaata tagtattttc aatagtttaa acaaacaaaa
     2581 atgtaataaa aaaggtgatt tgccacccat ttgccaccat aattataatc taatggcaaa
     2641 ttgttttaat gtacaaacta gataatagaa tattgtttta aatgctatat tatgctaaaa
     2701 tttaattgta ttttgtaaat taaaaaactt ataatttagt tttctagggt tccgcatttt
     2761 ataatggtca ggtccaagag aaaacgcgca attgttgtgt acacggaagg ataaaagcct
     2821 gggagatatt taataatatt tctataggct tttttatttt tacatatttt aaatttgagg
     2881 aggttttcta atgaaaaaat ttgttattga ggatgcattt tggaatctat ttcctagtgc
     2941 aaaaattgga gttattattt gtaatgatat agataactct ataaaagatg aagactataa
     3001 gaaaataatt ttgaagggag aagaagaagc attaaaatac ttggaggact cagaatttag
     3061 caacaaccaa gtgattaaag tatggagaga ggcatttaaa aaatttaaaa cgaaaaaagg
     3121 agcaaggtct tctattgaag cattattaaa aagagttcat aatggaaata atataggaac
     3181 tattaaccct ttagtggata tctacaattt tatctcatta aaatatgcat taccttgtgg
     3241 aggggaggat atagataaat ttataggaga tattaggcta actagagcaa ttggtaatga
     3301 ggagtttatc ccactaggga cagatgaaaa ttcatttcca tatgaaggag aaataattta
     3361 taaagatgat ggtggagcaa tttgtagatg ttggaattgg cgtgaagcag tgagaacaat
     3421 gcttactgaa gatactaaca atgccttttt atgcattgaa ttagtagatg aaagtagatt
     3481 taaagaattt gaaaatgctt taaatgaatt agctaaaata gttcaagaaa aattgggtgg
     3541 gaattgtaaa atttcaattt tagatattga taataaagag gtatcagtgg attaatctgg
     3601 agatgctgtt gtaatggact attctagtta taaagatact tatatttagg gtaataagtt
     3661 ctattttaga tgtaacgatt atcaaaggat ataatataga aaataaaaat gtagaatata
     3721 aaaagccttt aaaataagaa aaaaatgtat tttaaaggct tttattatac tcttttttat
     3781 ttgcataatt aacaataaaa atatattgtt aattataata tttttattga aaaacgatat
     3841 aatataatgt attatactat atataaaata ttttaaagga gttggtatga tgcctaataa
     3901 acttataaaa aatttactaa gtggtatatt acaaatttta ttttttcttt tagggttagt
     3961 aattgttgtg ggaggattta aaagttttat gtacctctgt tttagtggag aagcaactct
     4021 acaaggcact atttctggaa tattaatgtt tattttaggt gtatcatatt ttatcattat
     4081 aaaatcattg atagaagtat taagtagttc tgaacatagc ttatttgtaa aagataatgt
     4141 aaaaagattt aggattattg gatatctttt gcttttaaac tctataatgg agtttatttc
     4201 aacttttggt actactggaa aaggaatgag attcctagat ttaggatttg gattttattt
     4261 tactgttcca gtatttgtat attttataac ttctcttatg agttttgtaa ttgcagatgg
     4321 atttgtaaag gcaataaaga taaaagagga taatgattta actatttagg tgtgacactt
     4381 taatatatag gagataaata accagaaaag agtgattaac tagtaattta aaataaaata
     4441 tattagggta taatacataa actataatgc taaaattaaa agattataat actaaa
//
LOCUS       DAEQJM010000141         4343 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.144, whole genome shotgun sequence.
ACCESSION   DAEQJM010000141 DAEQJM010000000
VERSION     DAEQJM010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4343
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.144"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(732..1142)
                     /locus_tag="KRQ43_003607"
     CDS             complement(732..1142)
                     /locus_tag="KRQ43_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743939.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(1358..2740)
                     /locus_tag="KRQ43_003608"
     CDS             complement(1358..2740)
                     /locus_tag="KRQ43_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH2743940.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKSGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIEQSNYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(2751..3110)
                     /locus_tag="KRQ43_003609"
     CDS             complement(2751..3110)
                     /locus_tag="KRQ43_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH2743941.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(3315..4094)
                     /locus_tag="KRQ43_003610"
     CDS             complement(3315..4094)
                     /locus_tag="KRQ43_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBH2743942.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         1528 a          705 c          402 g         1708 t
ORIGIN      
        1 tatctatttt tttctggtat tcttatctac tattatccgt atatttattt tatgattact
       61 cttttaacct accccctata ctttatagta atatgttttt aacctttttc attattccca
      121 atatgcttta taactacaaa tactctcccc ccttaaaaat aataataaaa ttaatcaata
      181 aatttataat catattatta ctctatgtat taagcaatta ctatgccaat aaattttgat
      241 ttttttaaac aaatcttaaa aatcctaaaa tgctaatttt ctttaacttt taatgaatct
      301 aatagataat atttaatttt cgttatattt ttcagaatgt ttcaattatt atttttaaga
      361 aaaaaaaata atgttaacat ttcttaacat acattaaaaa atgttaacat tataaatttg
      421 gtttaatact tttactttga ctcgatttac ttttattcta cttcttactt tatttttaac
      481 ttagacttta tttttttatt acttatttga gtcttattta ttttattctc actccatatg
      541 ttcaattaca tttgtctaaa ttctttgata cttttattac ataattttaa caagcttaag
      601 tgttatttgg gtagtgcagt tgataattat ttaaataatc atcaactgca tgtttatatc
      661 attacagtag cttaatgtat ttaatcatac ttacttagga ttttgaaata tcttagagat
      721 tatatttaac attagtcaat tgctgcataa ttgtaagcaa ttgaaatttg agacccatct
      781 tcattttcta tagtgatagg cttcataatt tttaatcctt cagtttttat cttttctaat
      841 tcttgttcca ttttcttaat tgtttcctca aggtcttttt gacttacatc tttgactgca
      901 ttagggtctt tagcatagtc ttttaattct tgaatatgtt tagcatactc ttcataagta
      961 taatgctcaa caccatactt ttccaattca gtagggtcag ttattcctga ttttattaga
     1021 gattcaagtt taggtaaagc aatattagat gaatcatttc catttgcaaa tactgctcca
     1081 gttcctccta gtaccattgc agataccatc attgcactta taagggattt ttttattttc
     1141 ataaccaatc ttcctttctt agagatttat ttgggtagtg tagtttaaaa tgactattgc
     1201 aatagttatc aaccacatct ttagactacc atagtagtca tatttgtgtc aagtcttttt
     1261 aaaaaacttt tcaataaaaa atactatctc aaaacaaaat taattatttt gagatagtat
     1321 tttaattcta aatcttttat attactaaga tttatggtta ctctatccat gttctatatt
     1381 gttctttatt aactgctaac aaattccctt ttcttgatat gacaaagcga ttatcattat
     1441 agttactttg ctcaattgaa acttctcctg aatcagtata aagtacatcc ttactattac
     1501 tagatttatt tacatacgtt tcttcactat tctcagaatt agttactttg ctcatagatg
     1561 attcttcatg ctctctaaat tcaattacag atacttttgc cgtactaaaa tgagtctctc
     1621 catcactttt agctttacta acaagaatat cagattctac tttgggagaa tataaatcag
     1681 ttgatttact acttattgaa aatccacttt tatcactttg ttcatttttt gttaaaccaa
     1741 aagattcaac ctcattaatc tctttatttt ctgttgcaaa aacaagacct gtcccacaaa
     1801 ctaatacagt tgaaactaaa aaagtaacat aagttgattt tttaaatttc ataatattaa
     1861 ctattctctt ttctattttt gtctttccaa atccactaca tattgtcatt gaaaatggat
     1921 tattctcctc tgctagactt attagtgtgg ttgcataatc agccctatat tcttcaccaa
     1981 gtatactcat aaccttttca tcacaactaa attctatgtc tttatttagt aaaaaaaaca
     2041 tcacccaaac taagggatta aaccaatgga caacaagagc tacaagcata aataacttta
     2101 acagattatc aaagctatta atatgaacca tttcatgagt taaaacaaag tctaaagttt
     2161 gattattagc ataattcatt tgctttggca aaataattcg tggttttaaa ataccagatg
     2221 taagtggtgt cctagtaaat tcagatatgc aaacaataaa tcttctaaaa cggctattct
     2281 tacacatcca ttttttaatg aactcatgat tttttatatg aattgaagtt ttaaaaagat
     2341 taattatttt aaaatatcta aagcataaaa gtatgctaaa cataatagta actataaaag
     2401 acaaaatgcc caacatttcc aacatcataa tattttcaat attagacatt atttcaaatt
     2461 cgtcagaatt gtttttacct gtagagtcac tagctttctt aagagtataa ttttctgttg
     2521 atgtattacc caattctaca tcaaaagtcg attcaattat actataaata ctaaaaccag
     2581 aatttaaact tactggtatt agaagtttaa ataaaacaat caaccacaat aatacaaata
     2641 cctttttagg taatttttta aataaacatg ctcttataaa aataactatt aaaagtaata
     2701 ctccagaagt aaaactcatt tctaacaatt taatgaacat aaatcttacc tcactttaat
     2761 ttttcaacaa tttgtttgag ttttgtaatc tcatcacttg aaagattttc tttattaata
     2821 aaagctgaaa gaaatttttc tgaagaccct ccaaacattt tattaattaa agtttctgtt
     2881 tcctgttttt gtacttcctc tttgcttatt aaagctttac aaacaaaatt tggctcaatt
     2941 ctctctattg caccttttga cactaatttt tttataacgg tatacgtagt gtttctattc
     3001 catcctgttt cttcttttaa aatttttact aactctccag ccttgctttc tcctctctcc
     3061 catagaactt ccattacttt aagttctgaa tcaaataatt ttatctccat ataaaatcgc
     3121 tcctcaaata tagttatcac aatagtcatt actataataa aaaactatca tagtagtcta
     3181 tactatgtca atcatttatt ttttaataat aaaaactgtc tttttaaaaa attcttataa
     3241 aagacagttt tatcaatgtt atactttaat gtttaattaa agccatattt tatttaaatg
     3301 tataactatc tatcttagta catagtataa gatttttctt tatctaatag tatatcctct
     3361 acatctgggt tttcttttac taattgtcta taaaaattac aattagtaac acctacatat
     3421 ggaattagcc atagtagacc tattccaaga gtagctattg aaagtatata ccatcctata
     3481 aaactaaagt ttagtacaaa taatttaagt acatttcctt tcatcatatc taaactagca
     3541 cccattgatt taaatacacc catattatcc ttgtcttcac aaattaagaa agtagcttga
     3601 gaaacatata atagcaatat ataaaccggt aacataagaa caagtattat aagaactaga
     3661 gttattccag tagaaataat agtccctatt ccaacattat cacttgataa atattcaatt
     3721 gctccactag taagtaaaac tccaaatgat aaaaacgctc ctataattgt gattataaaa
     3781 gaataaatat aaacaataat tgattcaaat aaataaaaac caaaacttct taaataaatt
     3841 ctcccactta caaagatatc tcctatcttg actttttcat ctttagtaat tttcaagaac
     3901 atacatgtaa atcctgctga aacgcaaaaa gctattacag ccactacaat agtagtcaat
     3961 ggttcaaaag gtaatcctac aattgatatt aatactatca atgcaatata tactgccata
     4021 gaaattgcac atattcccca gtttccagat aactgagctt tagatactcg ttttaattct
     4081 tgccttgata ccataaaaaa cacccctttc attttataaa aaaactttta aaaatataaa
     4141 taatctttta acgtataata ttaatatatc atattttcga ctatataaga tacaattatt
     4201 caccatgttt tatcaagata tgccataatt gtattactag ttttatatag tcaacattac
     4261 caaatacatc aaataaattt gattaattat tcaacaagta ataaaataat ttctattaat
     4321 tgtactttat ttagtaaaca aat
//
LOCUS       DAEQJM010000142         4108 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.145, whole genome shotgun sequence.
ACCESSION   DAEQJM010000142 DAEQJM010000000
VERSION     DAEQJM010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4108
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.145"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(197..1489)
                     /gene="brnQ"
                     /locus_tag="KRQ43_003611"
     CDS             complement(197..1489)
                     /gene="brnQ"
                     /locus_tag="KRQ43_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH2743943.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLI
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIKFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
     gene            complement(2607..3899)
                     /gene="brnQ"
                     /locus_tag="KRQ43_003612"
     CDS             complement(2607..3899)
                     /gene="brnQ"
                     /locus_tag="KRQ43_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH2743944.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFALSYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVDVPVV
                     KSLPLHSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         1431 a          690 c          448 g         1539 t
ORIGIN      
        1 tttaatttta tttataatta taaataaatc ttttttattt tattgtcttt ataaatcata
       61 ctcctccaaa aataaattta tcaaatgaga ttaataatgt tcttttctcc acaataattt
      121 aataattctt ttaaatataa aaaggaattg ccatataatt taaaggcaat tccacaatta
      181 tcaattagtt ttattattat gcagttttac tgcttttaga tggaataaag tttcctatta
      241 ttcctgctat tacaactgga actatccagt taaatcctaa tgaagcaaat ggtaagctat
      301 taactagagg aatttttaca ccaaaacttg ttgcaactgt taatacactt actaataatg
      361 ccatgtatgc agcacatttg aacacgttgt catttttaat tttattacta aataatgcta
      421 gtataactag agttatagtt gctggatata ccatacttag tataggagaa gagaatttta
      481 ttattgtact tactccaaag tttgatatga ttgcactaaa tacacaaact actataacta
      541 tatgctcata ctttaatttt ccatctgtaa gtgttgagaa atattgacca gctgctgaag
      601 aaagacctat agctgttgtt aaacatgcta atgcaactat aatagccaat aaaattttac
      661 ctgtagttcc aagtaaagct gctgttattg caactattaa agctgtttgt tgaacatctt
      721 gtccatattg ttgagacaca gttgctccaa gataacataa tccaccataa actaatgcca
      781 ttcctattac tgcaattaca cctgcactta ttgtggcttt catcttttct ttctcacctg
      841 tataaccttt agctattact gacatgatta taattgatgc aaatacacta gctgccaatg
      901 catccattgt ttgataacct tgagttatac cttctgcaaa tacattttga attaaagaac
      961 tgtctcttat ttctcctaat ggagatacga tacctttaac tattaatact gctaaagcta
     1021 taagtaaagc tggagttaat attgacccaa ctatatctac aacttttgat ggtcttattg
     1081 ttaaaaccaa tactagagca aagaatacta tagagaatat tactggactt attccagaac
     1141 ctattgtagg caatataccc atttcataag ttgttgctgc tgttctaggt attgctaaaa
     1201 gtggccctat acagattacc attgcacatc ctaatgcaat acttaatcct ttgcctgctc
     1261 ttgagaacat cttcgatgtg tctccattga acttagttgc tgctataact gctaataatg
     1321 ccaaaccacc atctgcaaaa aggaatccta tgaaagctat tagccaacta cttccagata
     1381 aaactcctag atatggaggg aagattaagt tccctgcacc aaaaaacatt gcaaatagtg
     1441 caaatccaat tacaattaca tctttaaaat tgatttgttt ctcacccatt taaagcaccc
     1501 ccatttgaat tttactacct tttactaaaa aataagtcca atctcttcat taaatgaaaa
     1561 ccttttgacg agattttatt taattataca tttttgactt aaatttgtca attatgtttc
     1621 ataatttata aaatcttcac aatatttaat acaactttct taattaaaca aaatcaacct
     1681 gtatacttta aacatagttg gttttttgtt ttttctctaa ttttccttga taaaattaac
     1741 tattcagaac aattaaaata ttaagacttt ttagattatt cgttttatta ttaagttgta
     1801 ttgctttata tactgtatat atcactctcc tttttacatt catataatct ttttaattca
     1861 atttaaattt taaatatttt gtgtttatta tataatctga aaaaaaagca gtcaatagca
     1921 tttttaattt ttttaatttt caaaattatg attcttaaaa aatcgttttc cttttatcat
     1981 aacacctatt aacgttaatt cttgtagtat tttgtattta ttttgctaaa ttgacagtta
     2041 actttattca atttttattc tactcacgta gatttacctc ttgtctttta gtcttaaaac
     2101 cattttttct gaaaattcct tattatgatt tatcaactta tttttcttca tagcaattac
     2161 tttctaactt ccaacttact taaactttgc agttgctagt attcacgttt acatacttat
     2221 atgtcataat taactaaaaa ttcttaatat atctctcaat gaaaacaatt tactcattta
     2281 tttaatacat ttatataatc atatgtctta aattttgttt tattatttta ttattgtcac
     2341 aattttattt atattatatt tttgtaaaaa tcatttaata tgtatactta aatttataaa
     2401 attactctaa aattcttttt taatctctat tattgttaaa aaataaacta tatatttttt
     2461 tgatattttc ttatactttt tccatattaa atacaaataa ttaattatag aatcccaaaa
     2521 taaaaggagt tatttgtaca aataactcct tttactttta gttaactcat ttatttacaa
     2581 ttgattatat tttaattaaa caaaacttag tttgttccaa gtgtattaga ttgactcttt
     2641 gatggtataa aattaccaat tattccagct attataactg gtaccaccca gttaaatcct
     2701 aatgaatgaa gaggtaaaga ttttactact ggaacatcta ctccataact agatataact
     2761 gttagtatac ttacaagcaa tgacatatat actgctcctt tgtacacatt atcattctta
     2821 attttttcat tgaagaaagc taaaattatt aaaacaattg atggtggata aactatactt
     2881 agtataggag atgctatctt tattatagtt ccaacaccaa aagatgctac tactgcactg
     2941 aatacagata cagctaatac tattttttca taactcaatt taccttttgt aagtctagag
     3001 aaatattgac ctgtggcaga tgtaagacct atagatgtag ttaaacatgc taatgatact
     3061 actactgcta aaatcgcttt cccaacattt ccaagtaatc cttcagttat atttactatt
     3121 acttgtgatt gtactgcatc tgttccatac attgttgata cagttgctcc aaggaaacat
     3181 aatcctccat aaactagagc taatcctcca caagcaagaa cccccgcctt accaatcatt
     3241 tttaacttgt cactaatagt agaatatcct ttatcattta aagatactat taacactgat
     3301 gcaagtgcta ttgctgcaaa agcatccatt gtctgatatc cttgacctat accttctgca
     3361 aatacattag gtatcatagg tttatctact atatctccaa gaggtgatat aatacctttt
     3421 ataattataa atgctagagc tattaaaaga gctggagtta aaaactgtcc aactatatct
     3481 acgaccttag aaggtcttat tgttagtaca tatgaaagcg caaaaaaaag tatacagaat
     3541 aataacactg gaattgaagt tccaaataaa ggcattatac ccatttcata agttgttgca
     3601 cctgttcttg gtatagctaa gaatggacct atacataaaa tgtctgcaca acctataaga
     3661 atccctaact tcataccaca tcttttaaac atttcaacta cgtttccatc gaatttagct
     3721 gtagccatta ctgctagaag tgccaatcca gcatcagcaa acgtaaatcc taagaaggca
     3781 attaaccatt ctggacctgt aattattccc aagtaaggtg gaaatattaa gttacctgct
     3841 ccaaagaaca ttgcaaataa cgcaaatcca aatactataa catccttggt cttacccatt
     3901 ataaaatccc cctttttaac cttattaaat taataaaatg tctcgattgt ttacgcttgc
     3961 ataaataaat taaattaaac aataagaact tattattaaa ttaataaaat taaataaatt
     4021 aaatttttaa tatattgtat ttatttgtgc ttattatata ttatacgaaa caagcaagtc
     4081 aatatgctaa aatttaaaat aatcacac
//
LOCUS       DAEQJM010000143         3986 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.146, whole genome shotgun sequence.
ACCESSION   DAEQJM010000143 DAEQJM010000000
VERSION     DAEQJM010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3986
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.146"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..532)
                     /locus_tag="KRQ43_003613"
     CDS             complement(<1..532)
                     /locus_tag="KRQ43_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743945.1"
                     /translation="MSNQIKDFDITNDMFQESIPITTKTILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLVKAANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLE"
     gene            complement(942..1118)
                     /locus_tag="KRQ43_003614"
     CDS             complement(942..1118)
                     /locus_tag="KRQ43_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743946.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1172..1268)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            2064..2465
                     /locus_tag="KRQ43_003615"
     CDS             2064..2465
                     /locus_tag="KRQ43_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HBH2743947.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     gene            2462..3529
                     /gene="rsgA"
                     /locus_tag="KRQ43_003616"
     CDS             2462..3529
                     /gene="rsgA"
                     /locus_tag="KRQ43_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH2743948.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKSGCTVALLGSSGVGKSSLINC
                     LLGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKTIRR"
BASE COUNT         1423 a          499 c          592 g         1472 t
ORIGIN      
        1 cttctaactt atatttttta aaatcttctt caattttatt tttattactt ttattaatgt
       61 taacagaatc tcttttaaat ttatcaatat atttttctat ttcattaata ttatctttgc
      121 ttacaactat accacctttt aaattaaaaa cttttttgaa attcttttca gaaaatcctt
      181 gaataaaata actttgtcca tctccattaa tactatcttg agtatcaaat acttcaattt
      241 ctttgttagg tattggtata tcaaaattcc aagattcctt tagcattgaa atattagctg
      301 cttttactaa aaaaagatta tataggatac ttcctaataa caaaacacct attaatagta
      361 gtgtgattaa tacaattttt ctctttttca tttttcgttc acaacctttt gaaaaaacat
      421 gatttaattc atcatttgaa ggcatgtctt caagaatagt ttttgttgtg ataggaatgc
      481 tttcttgaaa catatcattt gtaatatcaa aatcttttat ttgattactc aatatccatt
      541 tcttctaata tttcttttga ttttttctag tacattgaat actcttatat acattctcct
      601 cttttaaaat taaaagttat aaaagaataa gttatataaa aaattattat attttttaat
      661 atagcttatt tgcaaattta taattttgtt aatctaatcc ttcaaactaa aaaatcattt
      721 atgtttacag aatttcattt taagagatgt ttattttcac atagataaga gaatttaagt
      781 tctcatattt attatttgat acaaatttac atctttatta tatgtatttt aaatagaaaa
      841 taaaattatg aatactagaa atctatctta attagctttc taacataagg ctatttaaag
      901 tagataaaac taaaaagggt tctctagaaa accaaatcta tttaattata cttacttact
      961 aataccatca cttgatgcaa acaagattct accacatttt ctccgtactc tagtataaaa
     1021 tcatctagtt gtgtatctat aaaatcacaa taatcatatg aactaccaat ataagcagtc
     1081 aacatatgtg tacatctatc cattttatct ctaaacatat atattattat ccccctaaaa
     1141 aactttcata aaaacaaaaa gaatatctct ttttggcaac tggctgacat aactcatagt
     1201 ttattttata agcgttagtc cctatagctt tgcgtcacta aatttctcta gttttgccga
     1261 tttagtttta ttctacaatt acaataatac aatagaattg cttattattc aatatactta
     1321 tttgaaaatt aaataaattt acaaatatga acgttatttt atataaaaaa aatagactat
     1381 tcatgtagaa tatatggaaa aacttgattg taggttttgt atgaaaagac agttgttatt
     1441 aatttaagtg agataaattg agcaataggc ataaaatgag aaaacaaata atagcaatta
     1501 atttttatta ttaatactag gtgaacatta aattttaaaa taccactaga ttttatagaa
     1561 taagaaaatg agacaaacat aaatatatga atatattaaa ttatacttga acatacttat
     1621 attttatgat aaaattttaa taataattat tagtgaagga gtgtcttgcc tgatgtcaga
     1681 gttatatata atggtaacca acaaataaat agttggagac gcatatgggt tctgtttaat
     1741 cagaattttt aagtgtattt ttgatacatt tgattgttgt gtcttactct gcctttatag
     1801 ataactaaca ttagacaaca aataataata ttacatatta ctttgttaaa ttgtggtgta
     1861 gtgggcttta atctgctaca cttttattaa ttttacacag tattattttg aatataatta
     1921 tgttgaaata gaagatacta aattttctag tccacagggg ttttctgttt ttgtgtaggt
     1981 aaatatgtat accacataaa aaggcagata taaatacctg tggacttttt ttgtagaaaa
     2041 tacaagatac ggaggaaata aaaatgaatt ataaaaatag aaaacgagct tattatcagg
     2101 aaaattcctg tatggataac tttatttgca aaaattgtgg ttgccttgta gttcctgaag
     2161 gagctggtac acaacataga aatcattgtc cacattgttt acatagtctt catgtagata
     2221 tcattcctgg tgaccgtgct gcagattgtg atgctaatat ggaacctatt ggagtgtggg
     2281 tgagaaaaaa tggtgagtgg gcaattattc atcgttgtac acgctgtgga catcttagtt
     2341 ctaatcgtat tgcagctgat gataattcag tgaaattaat gtcaattgca ttaaaaccac
     2401 tggcacagcc ccctttccca ctagaaagaa tcattgaaaa gttggaaaag gaggaaacag
     2461 aatgaatggt atgaaacaaa tcaatttaca agactatggt ctaaatagga attttattac
     2521 tcaaagtatg gaatatcacg atttatacct tgctcgaatt atctcgcagg aaaagaactt
     2581 ttatcaagct gtatgtgtaa atggtgtact gtttgcagag gtttcaggaa aactgcgttt
     2641 tgaggctact atacaatctg attttcccac agttggtgat ttcgttatgt tggatcgttg
     2701 caataataaa aatggtaatg ctattattca tcatgtgctt catagaaaaa gcttgtttgt
     2761 gcgtaaggct gctggaaagg taaatgagga acaggtggtt gcagctaata ttgacattgt
     2821 ttttttgtgc atgtcactga ataaggattt taacattcat agattggaga ggtatctgtc
     2881 tttaacatgg gaaagtggag ctatcccagt agtagtactt actaaatcag acttatgtga
     2941 caatgtgcat cgtaaattac aagtagttaa ttctatagcc ttgggtgtag atgtagtagt
     3001 tacctcatct atagagccag atggttataa acagatttct aagtatatca aatcaggctg
     3061 tactgttgca ttacttggct cttcaggagt tggaaaatct tcattaatta attgtctgct
     3121 aggaggagaa tttttaaata caaaggaaat tcgcatagat gatgataaag gaagacatgc
     3181 cacgactaga cgagagctat ttttaatttc aggtggtggt attgttattg acacaccagg
     3241 tatgagagag ttgggaatgt gggatgtttc agaaggttta gataaaagtt ttgcagatat
     3301 agaagcttat ttcggaaaat gtcattttcg taattgtact cacacctcag aaccaggctg
     3361 tgctatctgg gaagctattg ctcatcaaga actttcgcct aaaagatggg aatcctatcg
     3421 taggcttaaa actgaagcag tatttgcaga caataaaagc gaatacttag caaaaaaaga
     3481 aaagaaattt aaaaatatct caaaaataaa taagacgatt agaagataag tgtagttttt
     3541 ttgttcattc tatgagtcta tatactatta atgtattaaa tttgccatta atttgttact
     3601 ttaatgtgat tttgatggca aatttggttt gtggtattat ttaaagcaat ttattaattt
     3661 ttttaataaa gtttgatttt ttatatgatg atatatatat gtgataatgt atacatattt
     3721 gttacgatag tctcctttat aaagaggtct tatgtaagat aagaaaaggc atatttatac
     3781 taatacataa tagagtatat gcttatgtat gatagagatg tttcttaaga gcaaaactgc
     3841 aatattgcta atttataaag taaaaatata tgaattataa aatacaaata agatatttat
     3901 aaaaattatt gttttaattt ataataaaaa ttttttgttg aaaacaatgc tcgaacctat
     3961 aaaactatta actaatattt gtaaat
//
LOCUS       DAEQJM010000144         3981 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.147, whole genome shotgun sequence.
ACCESSION   DAEQJM010000144 DAEQJM010000000
VERSION     DAEQJM010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3981
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.147"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            106..978
                     /locus_tag="KRQ43_003617"
     CDS             106..978
                     /locus_tag="KRQ43_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2743949.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            975..2264
                     /locus_tag="KRQ43_003618"
     CDS             975..2264
                     /locus_tag="KRQ43_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743950.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIDEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINLIWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFIMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            2194..2838
                     /locus_tag="KRQ43_003619"
     CDS             2194..2838
                     /locus_tag="KRQ43_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743951.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKSLSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPIKRKIR"
     gene            complement(3105..3569)
                     /locus_tag="KRQ43_003620"
     CDS             complement(3105..3569)
                     /locus_tag="KRQ43_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2743952.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLS
                     KEDKRKNFISFINDNKELIGFINLLDEGSYVFFGIGIKPDYCGMGIGKEIISLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYKSQGFKIVETQVQKTHLGDGEFFVMRYQ"
BASE COUNT         1493 a          469 c          606 g         1413 t
ORIGIN      
        1 gaaatttata aataatatct taagttttag aatttattat gaaaatacag taaaaattta
       61 taaaaataaa attctataaa attatttctg ggggtgtatt tatatatgga aatgaaaata
      121 gcagtatcca atcttagtaa aagatttggg aaaaaacaag ctcttgataa tataaatctt
      181 gaaatcgaca gtggtatgtt tggtctttta ggaagaaatg gagcaggaaa aaccacattt
      241 atgagaattt tagccacttt attatcaaaa acagaaggtt caatacatat gtgtggagtt
      301 cctattgaga atactaagga aattagaaat atggttggtt atttgccaca agatttttca
      361 atgtatccta acatgacagt atataaagca atggattatt tagcagtttt atcggatata
      421 ccactaagaa aaagaagaaa aattatagca aagttattaa gcaaagtaaa ccttactaat
      481 tatcaaaatg tgaaagtaaa atctttatct ggaggtatga atagaaggct tgggatagca
      541 caagcattaa ttcataatcc cagagtttta atagtggatg agccgacagc aggtcttgac
      601 ccagaagaac gtataagatt tagaaattta ctatgcgaaa ttgcaaatga tagaatcgtt
      661 attttatcta cacatattgt tggagatata gaagctacat gtgaaaacgt agctatattg
      721 gatagtggaa aagtcatata caatggctca acagaagcat tagcaaaact agctgaaggg
      781 aaagtatata gtattgaagt agataaaaaa gacattgaaa atataaaaag tagatttata
      841 gttataggaa tgttgactca tggtggaaag gctatactta ggattatatc agatgataaa
      901 ccttttgaga cagcagtaaa ttgtaatcca actattgaag atggctatat gcttataatg
      961 ggaggagata atatatgaat ctatttataa aagaatgtaa aaatatatta aagagtatgg
     1021 tatattatat ttttattgta gttttagttt ttttctatat ttctcaactt ggaagttcag
     1081 tttcaaatga tgtaagtaaa aatattccta atgatggaaa tccattagtt gctccacaaa
     1141 aagtagagaa tattgacgaa tattactctg tacacaatca atatccatat ggtcaaaaag
     1201 aatctatgaa aacagaaaag gtcattccaa atgcaactat aaacctaatt agagaatatc
     1261 aaaaaaacac atatacaacg tatccaacag gggtagttaa gtatataaaa ttagaccaaa
     1321 ataaaacgaa gaccatagaa aaatatatag aagaaataac tggtaaaagt attagcgaaa
     1381 taaatttaat ttggaaaact gatgaaagta taaaaataga ttattctaaa gtatctcttg
     1441 aaagatttga agaaataatg caaagagtag acgacatttt aggaggaggg tctgcatatg
     1501 cttttgacaa gttacaaaga tttggagtag ttccagttac ctatgatgaa gctatgaaga
     1561 attacaacta tacaatacaa aaagataaag ttagtaatgg gtatgcaaga attttttgcg
     1621 attatatagg tatagtttta agtatatttc cagtatttgt ggcagttttt atgtcactta
     1681 aagataagcg ttcaagaatg agagagatta tttattcaaa acaagtatct tcatgcaaaa
     1741 tagttttatc aagatatttt gcacttgtct ttataatgat attgcctgta ttaattttag
     1801 gtatgaaaga tttacttcct ttgattttct ttgctaaaga taaaggtata tctattgata
     1861 acttagcatt tataaaatat acattatggt ggatactacc aactcttatg atagttacag
     1921 ctgtaggaat gagtattact atattaacag atacaccagt agcaattatt gtgcaattaa
     1981 tttggtggct ttacagtata aattctacag gactcaaagg tgattattca acaatggggc
     2041 taatgataag acataatagt gtattaaatg gggatattat tatacaaaac ttcaatcaaa
     2101 ttatgattaa tagaattgtg ataagcttgg gagcattggt gcttgttttg ttagctatat
     2161 tcttatatga gcaaaaaaga agggggaatc ttgatgtttg ggcaaagttt tcaaaactgt
     2221 ttagttctaa taaaagaaaa cttcaaatta agcactttaa ctaatttaat atgttcaatt
     2281 atattgctat gtatgattcc tctaatacaa ggagtagcta atttagacag aatttcaaca
     2341 gctatatgtt tagaaaatta tgttgcaata atagggatag taatgttggt acctgtattt
     2401 tcgctagagc aatcaaaaga aattgatgag atagtatctt caaaatcatt atctcaagtt
     2461 attgtacaat taattaggat actgatgtca attataggta tagtggtatt aatcataggt
     2521 tttgtaaatg ttttaatata tcttggatgt aattttccag tagttgagta tattattgga
     2581 agtttcgcat cagctatgtt tataggaagt ttaggaatgt ttttctcaaa tttatttaat
     2641 aatacaatca taggttacat gatatctata ggatatttaa ttttaaatat gatgactaaa
     2701 ggcaagtatg ttggaaaatt ttttataatg tctatgagtc aaggtagttt tgatgagaaa
     2761 tattggctga tacttggaag tgttgtgttg ataattgcat ctctcttaat aaaaccaata
     2821 aaaaggaaga ttaggtaata aaatgagagc ttagataaaa taaaggtaat acaaataaaa
     2881 agtacattta tgaaatataa atttattttt atatacacaa acctacttac aatctcttta
     2941 tgtatgtaga tagatttata tatctgtagt ataaaatata tatgtatacc gaattttatc
     3001 aaaggctctc aaatttatat ttcaaagaca cttattgcta tgacatacac acatgtattt
     3061 tttcatttta attgtcatat tagcaatatg actagtgtta taaactattg atacctcata
     3121 acaaaaaatt ctccatcccc taaatgcgtt ttctgtacct gagtctcaac tattttaaat
     3181 ccttgagact tataacattt tacagctctc atgttccagg ttcttacatt taatacaatt
     3241 ggtttagtac tatatttatt tctacattct tgtaatccta ggctaattat ttctttgcca
     3301 attcccattc cacaataatc tggttttata ccaataccaa agaatacata acttccttca
     3361 tccaataagt ttataaaacc tatcaattct ttattgtcat ttataaaact tataaaattt
     3421 tttcttttat cttcttttga tagtgaaaaa ttcttctttt taatttcctc ccatggaggt
     3481 aggttgtata ttgaatattt accttcatat ttccaattag taacttcaat agcatgttct
     3541 tcagtaaatt taactttatt taaattcata tgtcctccta ttaaaatatt taaggtaatt
     3601 aatggtattt taaattttac aaaataagta aaactattta tatctatcca taaaatcttt
     3661 aaaaatttta ctaacaattc ttgtaccctg tactttttat tggattcaca gaagactata
     3721 aactaatttt gaattacctt ctaattcaaa aacatcacga tatatgtaat ttcttagctt
     3781 gattaaattc tgttaaatct gtttcttata gttgtataat caacatcaat atctttatgt
     3841 gtattagtta atttattggt tttaggaact tattattaat atattgtatt tgctccaata
     3901 ctccaagtag taggtaaatt ataggcaaat tatcaaatgt atatctatcc atgcttaaac
     3961 tttagagata caataactac t
//
LOCUS       DAEQJM010000145         3939 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.148, whole genome shotgun sequence.
ACCESSION   DAEQJM010000145 DAEQJM010000000
VERSION     DAEQJM010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3939
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.148"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..239
                     /locus_tag="KRQ43_003621"
     CDS             <1..239
                     /locus_tag="KRQ43_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005209661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743953.1"
                     /translation="VEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRTAIEF
                     STEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            497..1546
                     /gene="carA"
                     /locus_tag="KRQ43_003622"
     CDS             497..1546
                     /gene="carA"
                     /locus_tag="KRQ43_003622"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH2743954.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            1739..>3939
                     /gene="carB"
                     /locus_tag="KRQ43_003623"
     CDS             1739..>3939
                     /gene="carB"
                     /locus_tag="KRQ43_003623"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HBH2743955.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYL"
BASE COUNT         1630 a          400 c          777 g         1132 t
ORIGIN      
        1 gagtagaaga atctagacca aacatattag atgctataag aaataaacaa gttgatatag
       61 taataaatac accaactaaa ggaaatgact ctacaagaga tggatttaag ataagaagaa
      121 cagctattga attttctact gaaataatga catctttgga tacactaaaa gctttagtag
      181 aagttaagaa gaaacattta aataaagatg agttaaaagt ttacaatata gctgaataga
      241 aattaagttg attgtatagt ttaagaattt aattattaaa taaaaaaaaa gaggttattt
      301 tttctaggag tttttacttt tgagataact tctttttttt aagaaatttg tagtataata
      361 gaaaaagata aaaaataaat gtaaataagt ataaaactag aatgtaaaag tgaaaaatag
      421 atatagatat ttaaaagctt atatttagtt aatgttcttt agtttgtcta aagagaatta
      481 taggaggtac tgtagtatga aagcaaggtt aatattagaa gatggaacag tttttatagg
      541 aaaggcattt ggatatttag aagaaagtgt aggagaagta gtatttaata cttcgatgat
      601 aggatatggt gaagttttaa cagacccttc ttactatggt caaatagtta ctatgactta
      661 tcctcttgta ggaaattatg gtataaattt atcatcagca gagtctgaaa aagttcaagt
      721 aaagggattc atagtaaggg agaaaagtga ttctccaagt aattttagat gtgaaattga
      781 tatagaccaa tatttaaagc aaaataaagt tatcggactt gaaggaatag atacaagagc
      841 tttgactaag atacttagaa ataatggaac aatgaaaggt ataattacat tagaagacag
      901 taaattagaa gatgttaaac ataaattgga taagttttca aatacagaag cagttagaac
      961 tgttacaaga aaagaagtag agcatataaa aggaaatggt ccaaaagtgg ctgttatgga
     1021 ttttggagta aaaagaaata tattaagatc atttatagct cgtggatgtg atataacaat
     1081 atttccagct acaacatctc cagaagatgt attgagtata aaccctgact taatattctt
     1141 gtcaaatgga cctggagacc cagaagacct agaagatgtt atagaaaata taaaagctct
     1201 tattggtaaa aaacctatag ttggaatatg cttaggacat caacttttag ctttagctct
     1261 tggaggaaaa actgctaaac ttaaatttgg gcatagaggt ggaaatcatc cagttaaaga
     1321 tttagaagaa ggaaaagtat ttataacttc tcaaaatcat ggttattatg tttcagaagt
     1381 tcctgaacaa atgaaagtga cacatataaa tttaaatgat aatactgttg aaggaatgag
     1441 acatgagaag ctagatgtat acagtgttca ataccatcct gaagcttgcc caggaccaaa
     1501 agataatgac tatatttttg ataaattttt agaattagta aaataaataa cattagaata
     1561 gctaactaaa aaacaagaat aacttaaatc aaaaagtttg gtttaattaa catagatgta
     1621 ttaaatagat gtattgatga gtaaatttga acttaagata aaataaagta attaaagttg
     1681 attgtataga tgatgaagat aagaactgtg aaaattgttt agataaggag aaagagttat
     1741 gcctaaatta gatagtataa agaaaacttt agtattaggg tcagggccaa taataatagg
     1801 tcaagctgca gagtttgact attcaggaac acaggcctgc caagcattaa aagaagaggg
     1861 aattgaagtt gtattagtaa atagtaaccc agctactata atgactgata aagaaattgc
     1921 agataaaata tatatagaac cattaacaat agaatttata gaaaaaataa tagaaaaaga
     1981 aagaccagac agtttacttg caggtatggg tggtcagaca ggattaaact tagctgtaga
     2041 attacatgat gctggtatat tagataaata taatgtaaaa gttataggaa catctataga
     2101 atctataaaa aagggcgaag atagagattt atttagagaa gtaatgaaag aaataaatca
     2161 accagtaata gttagtgata tagttacaaa tttagaagca ggtcttgagt ttgccaataa
     2221 gataggatat ccagtagttg taagaccagc atatacgcta ggtggaactg gtggaggtat
     2281 agctgatact gaggaagaat taagagaaat actttcacat ggactacagc taagtcctgt
     2341 tggacaagtt cttcttgaaa agagtataaa aggttggaaa gaaatagaat atgaagtaat
     2401 gagagatgga aatggaaact gtataactgt atgtaatatg gaaaatgtag acccagttgg
     2461 agttcataca ggagacagta tagttgttgc tccaagtcaa actctaagtg atgaagagta
     2521 tcaactactt agaaaggcat caatagacat aataaatgca atagaggttc aaggtggatg
     2581 taacgttcaa atagctttaa acccacatag tttagaatat gcgataatag aaataaaccc
     2641 aagagttagt aggtcatcag ccctagcatc aaaagctaca ggatacccaa tagcaaaagt
     2701 agcagctaag atagctttag gttatacttt ggatgagata gaaaatgcag taactaaaaa
     2761 aacttatgct tgttttgagc caacattaga ttatgtggta gtaaaaatac caaagtggcc
     2821 atttgataaa tttagacatg caaatagaaa attaggaact aagatgatgg caactggtga
     2881 aatcatgagt ataggaagta actttgaggc tgctattctt aaagggataa gatcacttga
     2941 aacaggaaaa tattcattgg ttcatgctcc atcagaaggt agaacattag aagaattaaa
     3001 ggctagagta gtagtacctg atgatgagag actatttgac ttagctgaaa tgataagaag
     3061 aggctataaa gtagaaatga tatcagaaat aactggtgtt gataagtggt ttataaataa
     3121 atttaaatgg atagtagaac aagaagaaaa gttaaaagtt ctaaaaatag aagacttaga
     3181 taaagaatat ttacatgaat taaagaaaaa gggattttct gataaaggta tatctgactt
     3241 aatgaagata agcccagaaa aattatatga attgagaagt ttatataata tacaaccagt
     3301 ttataaaatg gttgatacat gtggaggaga atttgaagct ctatcacctt attactattc
     3361 aacttatgaa caatatgatg aggtagtagt tagtgataag agaaaagttg tagtattggg
     3421 ttctggtcca ataagaatag gtcaaggtat agaatttgac tattgttcag ttcactgtgt
     3481 aaaatcttta agaaaaatgg gaatagaaac tataattgta aacaataacc ctgaaactgt
     3541 aagtacggat tttgatacat ctgataagtt gtattttgaa ccattaacag aagaagaagt
     3601 tttaaatata atagaaaaag aaaaaccaga aggtgtaata ctacagtttg gtggacaaac
     3661 agctataaaa ttggctaagt ttttacatga aaaaaatata cctatactgg gaacagactt
     3721 tagagatata gatgcagcag aagatagaga aaaatttgat gatttactag agagactaga
     3781 tataaataga ccaaaaggaa aaggtgtatg gacaactaat gaaggtgttg aaattgctaa
     3841 ggagttaggt tatccagtat tagttagacc atcttatgta cttggtggtc aaggtatgga
     3901 aataacttat aacgaagaaa aactaattca gtatttgga
//
LOCUS       DAEQJM010000146         3806 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.149, whole genome shotgun sequence.
ACCESSION   DAEQJM010000146 DAEQJM010000000
VERSION     DAEQJM010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3806
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.149"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            50..577
                     /locus_tag="KRQ43_003624"
     CDS             50..577
                     /locus_tag="KRQ43_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBH2743956.1"
                     /translation="MVFANTTTDVDTSKDDDSIISSCTITGYEFTYENAPQSVKFDYE
                     KKCEALNIKPSKNDIIFVNKDSIDANDVENYVEPKAYIIRYKKGYVFEVTGPKSYTLN
                     VSNTVVGYNRVESGNPVHLVQLLCRTLDGSSIDDDSEFGPATYNAVKSLQGRLGLTRD
                     GIVGRSTWDAAGRRL"
     gene            complement(955..1716)
                     /locus_tag="KRQ43_003625"
                     /pseudo
     CDS             complement(955..1716)
                     /locus_tag="KRQ43_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612258.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2326..2703
                     /locus_tag="KRQ43_003626"
     CDS             2326..2703
                     /locus_tag="KRQ43_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH2743957.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            2696..3730
                     /locus_tag="KRQ43_003627"
     CDS             2696..3730
                     /locus_tag="KRQ43_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH2743958.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENAVGNNITQIDISTDNNLMLYVAYLWLVVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDVNCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLTDCSLKDKKEYALALIKSIKLSKNYNSGILTTEFNKTSLE
                     KRLDSIVKKKGKNGILVLLILITLFSVTYFNFESISFDNSNSLRNMGILQKSGVDLKE
                     EDDISMRVIN"
BASE COUNT         1427 a          401 c          539 g         1439 t
ORIGIN      
        1 aaaaaaaatt ttaataatta caggttgtct aactctaata tctactagtt tggtatttgc
       61 aaatactact actgatgtag atacatcaaa ggatgatgat tcaataataa gttcatgtac
      121 tataactggt tatgaattta catatgaaaa cgcaccacaa tctgtaaaat ttgattatga
      181 aaaaaaatgt gaagcgctaa atataaaacc atctaaaaat gatataattt ttgttaacaa
      241 agattctata gatgcaaatg atgtagaaaa ctatgttgag ccaaaagcat atattattag
      301 atataaaaaa ggttatgttt ttgaagttac tggacctaag agttatacat taaatgtaag
      361 taatactgta gtcggatata atcgtgttga atcaggtaat cctgtgcatt tagttcaact
      421 tttatgtaga accttagatg gttcaagtat tgatgatgat agtgaatttg gacctgctac
      481 atataatgca gttaagtcac ttcaaggaag acttggatta acaagagatg gaattgttgg
      541 aagaagtact tgggatgcag ctggaagacg tctttaaaaa gaaagctatt gcacagataa
      601 ttttaaattg ctgaatctgt aaacatttac atgtattctt taaataaaaa tttatttttt
      661 aagtgataat taaattttta ctaatagggc tatggcttta aaaatcatag ccttattttg
      721 atatcttttc catttttgca aaagctatta accctttaag aaaatttctt gtttttttga
      781 aaaatttctt tcttcaaaat aaatacttaa atgagctaaa atttgagcac aatttctaat
      841 tttctgagtc catttttaag aaatatatat ggttgttaag tatagtgatt tgtgcaaata
      901 attatccaaa gtaaaaatag atttcaattt agtaactttt cttaataatc tattctaact
      961 tcccattgaa tttgtagtat atatcgatgt atttatttct tgagagtact taaaatatgt
     1021 tactaattca ttccaattgt ttcaccaacc tcttaatact attgtatatt gattgtacta
     1081 ttttttctct agtgatagct cacttaatgc tacctcttct gtaattgtag catatctttc
     1141 tttaaatctt ttacagattc ttttctattt ttatatgata cataatttaa agtattttta
     1201 atttgatgca caacatatct ttgtacttaa gtatcaggaa atatcgcttt aattgcatta
     1261 gaaaattcaa ctagtctatc tatagaagct gctattaata catctttaat tcccatgttt
     1321 ctagcatcta taagcacttt tagccaatac tttgaaattt cattttctcc aatccatatt
     1381 cttaaaacct cttttatgct acatatagct atatagactg ttttgtttat tattcgacct
     1441 cacttctaac tttataatgt atagcatcta taaatacaat tgaataaatt atattaagag
     1501 gtctaagtta ccatttatga gttaaaggaa taactttatc agtagtttta gttattagtg
     1561 aatgagataa tatcaattcc ataagtactt ttaagatgac ttaatatatt ttgagtagac
     1621 atgccttttg agtatattcc aatcacttga ttttttattc ctaatatatc attttctatc
     1681 ataacctaaa agttcattaa gctccgcttc taacatttaa tggattgtac tttcaaataa
     1741 atcttttagt atatcttgaa tatctgtaat tgttttggca tcatattctt caataaattt
     1801 ttttaatatt ttagtttttg ttaaacataa aaagtgaaca tcttcctttg tatagtagtg
     1861 atattttaat tatcacaact ttttagaaga atacaaactt tattttaaag acactgaaaa
     1921 tggtgttttt atacctttat ttgctatgta taattttact tataacataa acttatataa
     1981 aacagatatt ttaataacac aaaggtacaa ttaggagatt gttaaaattt attagatatt
     2041 actctagttt atttaaaaaa aagtattata atattccttg tgtgaaaata taggaatttt
     2101 tattaaatag ttttaatgtg taaataacat tctacactat tgtaattaaa tatgtaaaaa
     2161 gtaaaatatt taaatagata tattttaaaa tctaactttt aatattgtaa aaaaattaga
     2221 aatttaacaa aaagtacaaa aattcacatt tttttcataa agtgtttgac taaaaaattc
     2281 acatgttgta gaattaaggt agcaggagtt ttgagggagg tgtaaataat gataagaaaa
     2341 ataccacaag cagaactaaa agtaatgaaa ttcatttgga aagtagatgt tacagtgaca
     2401 tcaaaagatg ttattgaagc tatggaacaa aaatatggct ggaaacaaac tactacactg
     2461 acacttttat ctaggctggt aaaaagagga ttcttagatg ctcaaaaaat agacagatat
     2521 acacattaca caataagagt aaaacacaaa gattatttaa gttttgagac aaaggatttc
     2581 ctaagtaata tacatgatga ctctttgaga agcttaattt cagcattaca tgatgatgaa
     2641 aatataggta aagataagct agattttcta gaaagttatt ttgataactt aaaggatgaa
     2701 taattatatg ctatatgttt ttgaaaatct tataaagaca actattgtat gtagtcttgg
     2761 tatttgtcta ttattatttt tgaaaagata tttatttaag aagtttagta agagattcaa
     2821 ttattatatt tggttgataa tagtctttag aatgttactt tttctattta attatacaat
     2881 agtgtatgaa gtaaaagaac ccaaagaaaa tgcagtagga aataatatta cacaaattga
     2941 tatttctaca gataataatc ttatgttgta tgtagcttat ttatggttag ttgtaactat
     3001 agtcattgca gtttatacat ttataaagta tacaagattt aaaaatctag ttgttgatgt
     3061 atcttatgat attgaagata atgatgtaaa ctgtatctac aaaaacttgt tgaaagaatt
     3121 aaatataaaa aagaaaattg aattaagagg ttctgatgaa ttgataagcc cagcaggcat
     3181 gggattattt aaatcttaca tattcttacc agactatcct tatagtaaag atgaactaac
     3241 ttggattttg aaacatgaat taatgcattt taaaaataaa gatattttaa taaagttttt
     3301 agtgttatct gttagaataa tatattggtt taatccactt gtttatgtaa tgagcaataa
     3361 agtaaatcta gattgtgaat tatgttgtga tgaaagtgtt ttgactgatt gttctttaaa
     3421 ggataagaag gagtatgcat tagcacttat aaagtcaatt aaacttagta agaattataa
     3481 tagtggtatt ttaacaacag agtttaataa gacaagtctg gaaaagagac ttgacagtat
     3541 tgttaagaaa aaaggtaaaa atggaatatt ggtgttattg attttgatta cattattttc
     3601 agttacatat tttaattttg aaagtattag ttttgataat tcaaattctt taaggaatat
     3661 ggggatttta caaaaatcag gagtagatct taaggaagaa gatgatatta gcatgagagt
     3721 tataaattaa tagattaatg tatgtaatga aaaggtatat tgtcgtatta ttaataaatt
     3781 aggaggaatt atgaaatgaa aaattt
//
LOCUS       DAEQJM010000147         3799 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.150, whole genome shotgun sequence.
ACCESSION   DAEQJM010000147 DAEQJM010000000
VERSION     DAEQJM010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3799
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.150"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     misc_binding    388..626
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            690..2609
                     /gene="thrS"
                     /locus_tag="KRQ43_003628"
     CDS             690..2609
                     /gene="thrS"
                     /locus_tag="KRQ43_003628"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBH2743959.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            3377..>3799
                     /locus_tag="KRQ43_003629"
     CDS             3377..>3799
                     /locus_tag="KRQ43_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743960.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFC
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPR"
BASE COUNT         1477 a          395 c          692 g         1235 t
ORIGIN      
        1 atttagatat taattgtatt tatttatttg attgtgttac ttattaatag tatttaagta
       61 tttactgtac tacttattaa ctatattaag tattgattgt atttaagtat acaaaaccta
      121 aaaagagtac aaaaattaga agttagtttt aataaaaatt agttttagta tttatctagt
      181 catatctatc atgcatgtgg atacgtttta aaaattttaa atttatgaaa atattataat
      241 atcactataa atcaagagat taatttaata taaaaatata agaatattgg tttacagctg
      301 attgagatga aaaataatgg gtaattaata tattacatta atgttgattg atgtataact
      361 atctgttata atgaaaatat attaaaaatc atagtgttga agaggaagag tagagtagaa
      421 accattctca gagaatttgg gtctatggct gagagcccat gtaataggtc tatttgaaaa
      481 ctaccttgga gctgagctta ttagcagtat ttgtatttgt actatacgtg aaagtgctcg
      541 ggtgacgacc ttatagtcat caagagggtt gtatatactt gtatacgcca acttgggtgg
      601 aaccgcgaat taatatcgtc ccaaacatat ttggggcgat tttttattac aaaaaatcta
      661 aaaattattt caataaggag gaaaaaacaa tgattaaagt tgctttaaaa gatggctcaa
      721 taaaagaatt tgaaaatgct atttctgtta tggatgtagc taaatccatt agtgaaggat
      781 tagctagaaa tgtggtagca gcgtctgtga acggagaggt tgtaggtctg gaccacatta
      841 tagatactga ttgtgacttg aatttattta agtttgaaga taaagaaggt aaggaagttt
      901 ttagacatac atcagcacat atattagctc aagctataaa aagactttac ccagaagcaa
      961 agcttgctat aggaccaagt atagaaaatg gattctacta tgatatagat ttagaccata
     1021 gattagttcc agaggaccta gagaaaatag aagctgaaat gaaaaaaata gctaaagaag
     1081 atttaaaaat agaaagattt gaacttccta gaaatgaagc tttagagctt atgaaagaac
     1141 aaggagaaga ctataaggta gaacttatat ctgatttacc tgaaagtgaa ataatatctt
     1201 tctacaagca aggtgatttt actgatttat gtagaggacc acatttacca tctactaaaa
     1261 aggtaaaagc tgttaaatta caaagtgtag caggtgcata ttggcgtggt gacgaaaata
     1321 ataagatgct tcaaagaata tatggaactt cttttgagaa aaacaaagac ttagaagagt
     1381 acttacattt actagaagaa gctaaaaaga gagaccacag aaaattaggt aaagaattag
     1441 gattatttat gatacctgaa gaaggtccag gattccctat gtttttacca aaaggtatgg
     1501 aacttaaaaa tgaattatta aaattctgga gagaaataca cagaaaagct ggatatattg
     1561 agatagaatc tccaatcata ttaaatagaa aattatggga gacttcagga cactggtatc
     1621 attacaaaga aaatatgtat acagttaaaa tagatgatga ggattatgct ataaaaccta
     1681 tgaactgtcc tggtggatta atttactata actctcaact acattcatat agagatttcc
     1741 caatgagagt tgcagagctt ggtagagttc atagacatga gttatctggt gcattacaag
     1801 gattaatgag agttagagca tttactcaag acgattcaca tatattcatg ttaccagagc
     1861 aaattaagga cgaaataaaa ggagtagcta acttaataga tggtatctac aaaacttttg
     1921 gatttgaata taatttagaa ttatctacaa gaccagagaa ctctatggga agcgacgaag
     1981 agtgggaagc agcagaaaat ggattaagag aagctttaga agagttaggt ctaccatata
     2041 ctattaatga gggtgatgga gcattctatg gtcctaagat agacttccat ctaaaagatt
     2101 gtttaggaag aacttggcaa tgtggtacta tccaattaga tatgcaactt ccaagacaat
     2161 ttgataatac ttatattggt caagatggtg aaaagcatag accagttatg attcataggg
     2221 ttgcttttgg tagtatagaa agatttatag gtatattaat agagcattat gctggtaaat
     2281 tcccagtttg gttatctcca actcaagtta agatacttcc tatatctgat aaatttatgg
     2341 attatgcaaa tgaagttaag aaagagttat ttgataaggg tataagagtt gaattagatg
     2401 atagagctga aaaaattgga tttaagataa gagaagctca gcttgaaaaa gtgccataca
     2461 tgttaatagt aggtgaaaaa gaagtagctg ataataatgt ttctgttaga tcaagagata
     2521 aaggtgaaat aggtagtatt aaattagatg aatttatagc tagtatttca aaagaaattg
     2581 aatcaagaga aagtattatt caagactaat atataatata ttagtagcta agatattgtt
     2641 atataagata agtttaatca atatgttgat atgttgatac atagtgatta aatttatgaa
     2701 aagatgagta taattagagg tacagttaat catattttta tgattaatgt acctctagtt
     2761 ttttgtatgg tagatttatt aataaatata tcatagaagt gttttgaaca tggaaatatt
     2821 tatgtgcatt ctttaaataa aagtttattt tttgaatgat aattaagtgc ttgttggtaa
     2881 ggttatggct gtaaaaatca taactttatt tttatatttg ttccattttc ataaaaatta
     2941 ttatcccttt aagaaaattt cttaatcctc ttgaaatatt tcctttttag tctaaagtta
     3001 aatttctttc ttcaaaatga atatttaaat gaactaaaat ttaagtacat tttctaatct
     3061 tatgagtcta tttttcatag ataattgccc tataatagaa gaatctatgt tggggctatg
     3121 tggtgacaat aacagcattg tcagtgatta attaatgctt tataaatgat taattagtgt
     3181 tttatgttat ttttggactt accctctata catagattaa tttatttaac tttagatata
     3241 gagagaatgt caagtacata cacagacatt agagtttaag aaagtgttta tggagcaaga
     3301 acttttaaaa gaagtagtga cttagtttaa tttcaagaaa tgataaatac aaaagaggaa
     3361 aaagagaggt gttgaaatga tagaaaaagt agaagaaaaa tctaagatta ttaaaacatc
     3421 aaaagaatat aagcgaacta taattgaaga aaaagataaa gaatggacca aaaaattaaa
     3481 tgatatactt agtagaagta gtttttgtaa tgatgaatta gataaaatca aggcgttaat
     3541 tccaaaagag attttgacta atgaaaatgt tggagaagtt gtgactgaag atggatatgc
     3601 taagcccgag tatgatgagg tatttaaatc attgttcact ttaaataatg aatatgattt
     3661 acttgtaaat tttataaatg atattctaaa agatgctcca tatgctaaca ggaatatcaa
     3721 accgttcact caaataaaga gaataattag agttgaaact gatccaacaa ttaattacat
     3781 tggagagaaa agacctaga
//
LOCUS       DAEQJM010000148         3796 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.151, whole genome shotgun sequence.
ACCESSION   DAEQJM010000148 DAEQJM010000000
VERSION     DAEQJM010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3796
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.151"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(451..2838)
                     /gene="cadA"
                     /locus_tag="KRQ43_003630"
     CDS             complement(451..2838)
                     /gene="cadA"
                     /locus_tag="KRQ43_003630"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBH2743961.1"
                     /translation="MEANNLIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLIVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENASSKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFKEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELVPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALTIGESSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKFNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKAIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2861..3226)
                     /locus_tag="KRQ43_003631"
     CDS             complement(2861..3226)
                     /locus_tag="KRQ43_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH2743962.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3425..>3796
                     /locus_tag="KRQ43_003632"
     CDS             3425..>3796
                     /locus_tag="KRQ43_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743963.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNM"
BASE COUNT         1251 a          694 c          382 g         1469 t
ORIGIN      
        1 actatatcac cttaaaaata tttcgtcaat acttttttaa attatttttt aaaaatattt
       61 actttcttat attacataat ttattgaatg acagtcatac tgttggttta gagtatttta
      121 acacacacat tttgttgtaa aaattataac tattaatata atatatatac aatcataagt
      181 attataattt ttatgaatct aatttaaact taatatagac ttattaataa accttctatg
      241 tctaaatttt aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacac
      301 aatggataat gaatataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa
      361 gttaaaagaa acttattgat acctttcatt attacatact tcaatatata attataagtt
      421 ttttaaatag tatggattta catttatccc ttatctcata gctctcatag catttactac
      481 tgctataagt gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc
      541 agcacctagt atcataacta taatttttac tcctagagca aatattatgt tttgccacac
      601 tatcttatta gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt
      661 cataagcact acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat
      721 accaacatca gcacgagcta atactggagc atcatttatt ccatcaccta caaatgctat
      781 tttctctttt tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg
      841 aagtaaattt gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt
      901 ctcattatct ccagttaaca ttacaacttc ttttacccct attgctttta agcttcttat
      961 ggcattttta ctatcttctt ttacttcatc agatataact atataacctc tatatacttt
     1021 atcaacagca atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc
     1081 ttttttcata agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat
     1141 tccataagct gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata
     1201 gtaacttaat atagactttg ctattggatg atttgaattt acctccgcaa tagctgcata
     1261 ttctaataat tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc
     1321 tttagtaagt gttcctgttt tatcaaatac tactgtatct acacttctta aagcttctaa
     1381 atagttactt cctttaataa ggataccatt tttagatgca aacccaattc cactaaagaa
     1441 actaagtggt attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc
     1501 tctatataac caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat
     1561 taataaagca gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt
     1621 ttctgtcttt gattttttaa tgctagaatt ttcaacaagg tcaagaatct tagaaactgt
     1681 tgattctcca aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc
     1741 tgataagatt tcatctcctt tttcaacttc tctcagcact gactctcctg tgagtgcaga
     1801 agtatctagc atagaaactc catccactac tacaccatct aatggtactt tttcaccagg
     1861 ttttactact attatatccc ctacatttac ttcttctggt gacactacct taacttcaga
     1921 attaaatttt agatttgcat aatctggtct tatttgcata agtgaagtta tagactttct
     1981 ggatttacca actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc
     2041 tactgcttct gatgactccc ctattgttaa tgctcctact gttgctagag ccatcaaaaa
     2101 gttctcatca aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcgcc
     2161 acctactatt acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt
     2221 agctgtttga tatataccaa atatatatac aagtgctcca attataagtg gaactaattc
     2281 tttcttattt gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc
     2341 agtagaccct acttgtatat caagtcctgg ctctgttgaa tttattattt cttttatttt
     2401 atttataaca tcatcctctt taaagttatt acttatattt actgtaagtt ttttatttac
     2461 aaagtttaaa ttagaagatt caacttcttt taatttagaa accttgttat taatctcctc
     2521 tgcacaatgt gcacagttta atcctcctaa tataagctct tttttaattg atgttttact
     2581 agatgcattt tctttagaac ttatttgtat atcaagacct ggttctgttg aatctattat
     2641 atctattatc ttttctatag tagtatcctc attaaagctt tcctttatat ttactataag
     2701 ttttttattt ataaaattta agttggaaga tttaacttct tgtagtttag aaactttatt
     2761 attaatctcc tctgcacaat gtgcacagtt taatcctcct agtataaatt cttttttaat
     2821 taaattattt gcttccatat atattcactc ctctcattta tcatttataa gtttctctaa
     2881 tatgatttaa tccacaatca aatatctggc ttatatgact atcatctaat gagtaataca
     2941 ctgtttttcc ttctcttcta aactttacta atctagcctg ctttagtact ctaagttgat
     3001 gagatattgc agagtgagtc atatttaata aactcgctat atcacataca cacatttcat
     3061 ttgcaaataa tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt
     3121 ctgctaaatc atataacatc tcttcatctg gcatagttga tttagcctct gttactattt
     3181 cttcatgtac tatattacaa ttacaatcat ttatctcttc tctcatcttt aatcctccat
     3241 tgttttaata tatgaataac tgttcatatg ttcattatat gctatcattc ctaaatttgc
     3301 aacaataatt tttattaatt taatataatt agaatgcaca tattataaac ttttttaata
     3361 tatatattat tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt
     3421 taatatgagt aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagaccc
     3481 agcgaactat gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga
     3541 ccctcaaatt tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata
     3601 tcctaataat gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac
     3661 aaataataca tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa
     3721 catgaataat aatacgggta tgcctaataa tatgtctaac aatatgaata gtaatatggg
     3781 tatgcctaac aatatg
//
LOCUS       DAEQJM010000149         3722 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.152, whole genome shotgun sequence.
ACCESSION   DAEQJM010000149 DAEQJM010000000
VERSION     DAEQJM010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3722
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.152"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            329..598
                     /locus_tag="KRQ43_003633"
     CDS             329..598
                     /locus_tag="KRQ43_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH2743964.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIGQCRKWLEETVSN"
     gene            complement(815..1060)
                     /locus_tag="KRQ43_003634"
     CDS             complement(815..1060)
                     /locus_tag="KRQ43_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HBH2743965.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            1597..2157
                     /locus_tag="KRQ43_003635"
     CDS             1597..2157
                     /locus_tag="KRQ43_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin regulator"
                     /protein_id="HBH2743966.1"
                     /translation="MFFGNISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAE
                     PWFKMKDDEKKAIEAENQRKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYK
                     YKKVKFEGKVIQVIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGI
                     SAGTITYESTMGGKITIPGIAVEKIN"
     gene            complement(2492..>3722)
                     /locus_tag="KRQ43_003636"
     CDS             complement(2492..>3722)
                     /locus_tag="KRQ43_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase C80"
                     /protein_id="HBH2743967.1"
                     /translation="LYQNKFLTLNGKKYYFGSDSKAITGWQTIDGKKYYFNPNNAIAA
                     THLCTINNDKYYFSYDGILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPA
                     NTHNNNIEGQAIVYQNKFLTLNGKKYYFDNDSKAVTGWQTIDSKKYYFNLNTAVAVTG
                     WQTIDGEKYYFNLNTAEAATGWQTIDGKRYYFNTNTYIASTGYTIINGKHFYFNTDGI
                     MQIGVFKGPDGFEYFAPANTDANNIEGQAIRYQNRFLYLHDNIYYFGNDSKAATGWAT
                     IDGNRYYFEPNTAMGANGYKTIDNKNFYFRNGLPQIGVFKGPNGFEYFAPANTDANNI
                     DGQAIRYQNRFLHLLGKIYYFGNNSKAVTGWQTINSKVYYFMPDTAMAAAGGLFEIDG
                     VIYFFGVDGVKAPGIYG"
BASE COUNT         1317 a          488 c          539 g         1378 t
ORIGIN      
        1 tatagtcttg tagaatattc aaagagattt aaagtaatct atagtgttat gaaatattca
       61 aagagattta aagcaatcta taatgctgtg aaatatattc aaggggattt aaagtaatct
      121 atagtgttat ggaatattca aagggatttg aagtaattta ttgtgttttg aaatattcaa
      181 aaatattttt ggaatagttt ttataaattt accagtatta ataattttat gtttaacatt
      241 tagatgactt aaaatcaact atttgcactt ttgtagtcat ctaaaatcat tttataatat
      301 ttttaaataa tggaaaggat gtttgaacat gtttgaatca agatgtggtg tctgttgtga
      361 cagttgtaca aaaaaagaac aagtaaattg cactggttgc ccaactatgg aaaaaccatt
      421 ttggggtgga gaatgtaagg ttaaaacttg ctgtgaaagt aaggaactta atcattgtgg
      481 tgaatgtgat actttccctt gtgatatgct tttaaataag ggaaaagacc aaggctttga
      541 ccctatggta aatattgggc aatgtagaaa atggcttgaa gaaacagttt ctaattaatt
      601 gttttagaat gctttgttaa gtaatttatt taatcctttg ttaggtagta tgtttagtca
      661 tttattgatt ggtatattta tacatttatt gatgggtata tttagccata caaatagatt
      721 tacataaaat ttacgactaa aaaagagttg agtattagtt tttattattt aaacggatat
      781 tcaactcttt tttatatcta acttttttga ttttttaatc tttccaatac caccacttta
      841 atttttctgg ttctggattt tcagttgatg caaaatatac tgcacatctg tatacatata
      901 actgacatct gtctatgtgc tgtccacgca ttaaacattc cttttcatac atttgtgctg
      961 ggtttgcatc tttaagtgat ttaatagttg tatatcctaa catgattaaa gatttttctg
     1021 ttgctttccc tacccctgga attttttgta gttctcccat acttcacctt ctttctgata
     1081 tattattttt gtattatact tagtaccaga tattttttta ttatagttaa tatttaattt
     1141 tttattatat cactttattt atgctctttc atctatctat attttaccac ctctaaagta
     1201 ctgaatcatt taattacatc ataatatagt tttatacaaa taaaatactt tatgtttcat
     1261 ttaatatata aaattcacct tcaagaaaat tatattataa tctgacattt ttacctcatt
     1321 tttcaaaata tattgaatct tcttgattta ttttgtaaaa ttatgcttag gggaaatata
     1381 ttttaggaaa atatgaatat ataattttta gtcaactagt tattttaagt ttttaaattt
     1441 taaaataaaa tatatctaat aaaagggaga ttgtattatg ttttctaaaa aaaatgaggg
     1501 taacgaattt agtaatgaaa gaaaaggaag ctctaagaaa ataattaaat tctttaagag
     1561 cacaaaggat attgctctac tggcatttat tttggtgtgt tttttggcaa tatatcctca
     1621 ccagcttgtt ctgaagacca tgaggaggtc atttctaatc aaacatcagt tatagattct
     1681 caaaaaacag aaatagaaac tttaaatagc aaattgtctg atgctgaacc atggttcaaa
     1741 atgaaagacg acgaaaagaa agctattgaa gctgaaaatc aacgtaaagc tgaagaagct
     1801 aaaaaggctg aagaacaacg taaaaaagaa gaagaagaga agaaaggata tgatactggt
     1861 attacttatg accaattagc tagaacacct gatgattata agtacaaaaa ggtaaaattt
     1921 gaaggtaagg ttattcaagt tattgaagat ggtgatgagg tgcaaataag attagctgtg
     1981 tctggaaatt atgataaggt cgtactatgt agttataaaa aatcaataac tccttcaaga
     2041 gtgttagagg atgattacat aactataaga ggtataagtg ctggaactat aacttatgaa
     2101 tcaactatgg gtggaaaaat aaccatacca gggatagctg tagagaaaat taattaatat
     2161 tgttttgtat tatagttaat attttatatt atagtcaata tgtttaaaga tgtttttata
     2221 attgcaaata aacagttaca aggctctaaa ttagtttttg cttttagcat attatctatt
     2281 ttctatcaac tattaattat ttagtattaa tatttccata tatgaatttt attataaaat
     2341 agtcaagaat aatagattat taaatgatag aaaaatttta actaaaagtc atgtattaca
     2401 ataacacatg acttttaatt aaatctcaat atttattata taaaaataat ttctgagtat
     2461 cacaggaata attttttgtc aaacatatat tttagccata tatcccaggg gcttttactc
     2521 catcaacacc aaagaaatat ataacaccat caatctcgaa aagtccacca gctgcagcca
     2581 tagcagtatc aggcataaag taatatactt tactattaat agtttgccat ccagtaactg
     2641 cttttgagtt attaccaaag taatatattt ttccaagtaa atgtaggaat ctattttgat
     2701 aacgtatagc ttgaccatct atattgttag catccgtatt agcaggtgca aagtattcaa
     2761 atccattagg tcctttaaac actcctatct gaggtaaacc atttctaaag taaaaatttt
     2821 tattatcaat agttttataa ccattcgcac ccatagctgt attaggctcg aagtaatatc
     2881 tattaccatc aatagttgcc caaccagtag ccgcttttga atcattgcca aagtaatata
     2941 tattgtcatg taaatatagg aatctatttt gataacgtat agcttgacct tctatgttgt
     3001 tagcatccgt attagcaggt gcaaagtatt caaatccatc aggtccttta aacactccta
     3061 tctgcataat accatcagta ttaaaataaa aatgtttacc attaataatc gtataaccag
     3121 ttgaagctat ataagtgtta gtattaaagt agtatctttt accatcaata gtttgccatc
     3181 cagtagctgc ttcagcagtg ttaagattaa agtaatattt ttcaccatca atagtttgcc
     3241 atccagtaac tgcaacagca gtgttaagat taaagtaata ttttttacta tcaatagttt
     3301 gccatccagt aactgctttt gagtcattat caaaataata ttttttgcca ttcaaagtta
     3361 agaatttatt ctggtaaact atagcctgac cttctatgtt attattatga gtattagcag
     3421 gtgcaaaata ctcaaatcca ttaggtcctt taaatactcc tgttaccatt ttagattcat
     3481 tattagcatc aaaatagaaa ttatttcttt caatagtaat atatccattt tgaagaattc
     3541 catcataact aaagtaatac ttgtcgttat ttatagtgca tagatgagtc gcagcaatag
     3601 cattattagg attaaagtaa tattttttac catcaatggt ttgccatcca gtaattgctt
     3661 ttgagtcact accaaagtaa tattttttac cattcaaagt taagaattta ttttggtaaa
     3721 gt
//
LOCUS       DAEQJM010000150         3325 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.154, whole genome shotgun sequence.
ACCESSION   DAEQJM010000150 DAEQJM010000000
VERSION     DAEQJM010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3325
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.154"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            229..888
                     /locus_tag="KRQ43_003637"
     CDS             229..888
                     /locus_tag="KRQ43_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007860183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bclB domain-containing protein"
                     /protein_id="HBH2743968.1"
                     /translation="MGATGPTGADGATGATGATGPTGADGLVGPTGATGATGATGPTG
                     PTGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAAGTLT
                     NFAFSMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPGATVTL
                     APPLTGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVAGYASAGIAI
                     N"
     gene            1057..1818
                     /locus_tag="KRQ43_003638"
     CDS             1057..1818
                     /locus_tag="KRQ43_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH2743969.1"
                     /translation="MKNKIETSMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKMGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            2127..2405
                     /locus_tag="KRQ43_003639"
     CDS             2127..2405
                     /locus_tag="KRQ43_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743970.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGEYIYIPRKSNNKKEWGSSTS
                     TREDLSIRNMQIYEDYQVGYDLKYLSEKYYLSLKSIQRIVLQEKRKDS"
     gene            2698..3273
                     /locus_tag="KRQ43_003640"
     CDS             2698..3273
                     /locus_tag="KRQ43_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HBH2743971.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPETLEQFHTNDYNLAKQYAMNTELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
BASE COUNT         1265 a          423 c          650 g          987 t
ORIGIN      
        1 ccaacaggag cagatggatt agtaggtcca accggagcga cgggagcaac aggagcagat
       61 ggagtagcag gtccaaccgg agcaacaggg gcaacaggaa atacaggagc agatggagca
      121 acaggtccaa caggggcaac aggtccaaca ggagcagacg gattagtagg tccaacagga
      181 gcaaccggag caacaggatt agcaggagca accggagcaa caggcccaat aggagcaaca
      241 ggtccaacag gagcagatgg agcaacaggg gcaaccggag caacaggtcc aacaggggca
      301 gatggattag taggtccaac cggagcaacg ggagcaacag gggcaacagg tccaacaggc
      361 ccaacaggtg ctagtgcaat aatacctttt gcatcaggta taccactatc acttacaact
      421 atagctggag gattagtagg tacaccaggt tttgttggct ttggtagttc agctccagga
      481 ttaagtatag ttggtggagt aatagacctt acaaacgcag cagggacatt gactaacttt
      541 gcattttcaa tgccaagaga tggaacaata acatctattt cagcatactt cagtacaaca
      601 gcagcacttt cacttgttgg ttcaacaatt acaattacag caacacttta ccaatctact
      661 gcaccaaata actcatttac agctgtacca ggagcgacag ttacactagc tccaccactt
      721 acaggtatat tatcagttgg ttcaatttct agtggaattg taacaggatt aaatatagca
      781 gcaacagcag aaactcgatt cttactagta tttactgcaa cagcttcagg tctttcatta
      841 gttaatactg tagcaggata tgcaagtgca ggaattgcaa taaattagat tagataagaa
      901 aaggcttcta atatcgtatt gatattagga gcttttttaa gaatgattga tgaacatagt
      961 tttaatatta attagtgcgc atattataaa atactattat ataatataaa ataataacat
     1021 taaattggaa atatagaatt atctaggggt gatactatga aaaataagat tgaaacatca
     1081 atgaacaact ttgtaaaaaa ttatcataaa tcaaataata taactacaaa gtggcaagaa
     1141 cttttgtttg cttatgcatc tgctgaagat gatatgtttc agaagctaaa aagtgttgta
     1201 ggaacatctc atgctatgcc aaaagatttt ctggaaaatg gaaaaactat aattacatat
     1261 tttatacctt ttgatgaaag tgtaaataat agtaatattg gagggtttga atgttctgaa
     1321 atatgggcaa gagcgtacat agaaactaat atgttgattt caaatttaaa tgatttctta
     1381 tgtgaagaac tagagaagat gggggctaat tcatatgcta ttcctgggtc gtataatttt
     1441 gacagtgaaa aattggtaag tgactggtca caaagacatg tagcattcat agcaggtctt
     1501 ggaacatttg gtttaaataa tatgcttatt acagaaaaag ggtgttgtgg aagaatagga
     1561 agcataatca caagtttaga attagagcca actaaaagac cagaaaatga atactgcttg
     1621 tataaacata ataatagttg caaaaaatgt gtcaacaaat gcgtgaaaga agctttaaaa
     1681 gaagatggat ttaataggaa taagtgttat gaaatgtgta tgataaatga aaaaaaatac
     1741 acttatatag gtggttgtga tatttgtgga aagtgtatag ttggggttcc ttgttcggta
     1801 ataaatccct caagataaag gacttatgtt gattaataac tttaaatata tctaataaga
     1861 agaaaaaagt tagtctctaa aatagatgaa ttatgaaaat aaataaagat aatataaagg
     1921 ttagatgaag aagttatgtt aattgacaac tatttatact gctgatagac ttatatgtat
     1981 cgttgcaata tataaggagg ggtgagattt atgtttgatt taatctttat ttttgcatag
     2041 caagggctat tgcaaatata aaatttaata tataaatagc cctttgctat tcctaataaa
     2101 aaattattat ttaataggag tgcagaatga gctataaaaa agcaatacat atattaccag
     2161 aagaattact tgaattgata caggaatatg tagatggaga atatatctat attcctagaa
     2221 agtctaataa taaaaaagaa tggggaagta gtacgtctac tcgtgaagat ttatcaatta
     2281 gaaatatgca aatttatgaa gattatcaag ttggatatga tttgaaatat ttatcagaaa
     2341 aatattactt gtctttgaaa agtattcaaa gaattgtatt acaagaaaaa agaaaagata
     2401 gttaagaatg agccagtata gttttataat tatactggct cattttcttt tgataaaagt
     2461 gtttgaggta tagtttctta taagtggatg ctataattta aataatttca ataacttgta
     2521 cagcagataa cgaatagagt tgtaaagtat ctaataagaa gtagtagctt tttatatgtt
     2581 tgaaattaaa atttattaaa attaggaggt cttgttttga aaaaaatact tgattatatt
     2641 ccaccttttc ataactttct attaatttag taatcttata gaaaggaagt tgcatttatg
     2701 aaaaaaatta cttgggaggt ggaatatatc tcccagttac ctgtaattag gtattgtaag
     2761 aaatgtggaa aaaagactga atatatttgt tcaggtttat ttagggttaa tgctcaacat
     2821 aaatatttgg atatatggtt aatatacaag tgttcaaatt gtgattcaac atggaactca
     2881 actatatatt ctcgtgtcaa tccaaaaagc ttaaatccag aaacactaga acaattccat
     2941 acaaacgatt ataatcttgc taagcaatat gctatgaata cggaactttt acatagaaat
     3001 ggagcagaag ttggtattcc agagtataaa atagtaggac aagaaattaa tattaatgac
     3061 cttacacaag ttcatattat tagtaaatat ccatgtcagt taaaggtatc aacattatta
     3121 cgtgagaaac taggtttatc taggaaggta tttgacgaaa tgttggattg tgggattatt
     3181 agaagtaact caggagttga tttaaagaaa ggtaaattaa attatgaaat tatgttagat
     3241 ataggcaagg agaagcaaaa gtcttcaaat tgattagaat aactaactta atatattttc
     3301 aggaacatca tttaaaaaaa tagtg
//
LOCUS       DAEQJM010000151         3281 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.155, whole genome shotgun sequence.
ACCESSION   DAEQJM010000151 DAEQJM010000000
VERSION     DAEQJM010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3281
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.155"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     misc_binding    169..379
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            605..1420
                     /locus_tag="KRQ43_003641"
     CDS             605..1420
                     /locus_tag="KRQ43_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH2743972.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            1448..2125
                     /locus_tag="KRQ43_003642"
     CDS             1448..2125
                     /locus_tag="KRQ43_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH2743973.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            2184..2906
                     /locus_tag="KRQ43_003643"
     CDS             2184..2906
                     /locus_tag="KRQ43_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH2743974.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
BASE COUNT         1318 a          333 c          605 g         1025 t
ORIGIN      
        1 aagaaatagc taaaaatatg aaatatacta tttataatta caaaaataat atcaataaat
       61 ataaacagta gtatttagat aatttacaag taaaaattat taaaaaaata aaaaacttat
      121 tgacaaaaat attataagga agtacaattg tattaacaat ttaaggaaac aaatccaatg
      181 atagagaaag tagcatatat ggatttacag cgagttaggg gttggtgtaa gcctagcaat
      241 gaagtctatg tgaagagagc tctggaggag attatcagaa actttagtat gataattggt
      301 ttacccgcct taagggattg agaggataag tacttactta tcaaaaagag tggtaacgcg
      361 gatataattc gtctcttagc tgtaaagcta agggactttt ttgatttaaa aataaaaata
      421 tccatacagc ttaaatgcta acagtcacaa attttgaaag taatataagt atttatcaat
      481 aagagtggta acgcggtaaa gtcgtctctt agtcattaaa gactgagaga ctttttttgt
      541 aactcgaaac atttaagtat taaaatctga gggaaattat aattaaaaga gaggggtagt
      601 taaaatgaaa gtatttaaaa aattattaag tttaggatta gtattaggat tgacattatc
      661 gctagtagga tgtagtggtg gaggagaaaa aacaaagtta gaacaaataa aagacaatgg
      721 aaaattagtt gttggtacta gtgcagaatt tcctccattt gaatttcata aggtagtaga
      781 tggaaaagat tcaataaaag gattcgatat aatgttggct gaagaatttg caaaagagct
      841 tggtgtaaag gttgaaatta aggatatgtc atttgatgga ttaataggtg ctttaaatgc
      901 agaccaagtt gatattgttc ttgcaggtat gtctccaaca ccagagagag aaaagagtgt
      961 tgatttttca gaattatatt atttaagtag aaatgcagtt atagttaaag atgcagatat
     1021 agacaaagta aaaactgaag atgatttaaa gaaacttaga gttggagttc aagcaggaag
     1081 tatccaagaa gaatatgtag ttaacacttt aaaaatgaca actacaaaat ctttaaaagc
     1141 aatacctgat ttaattacag aattaaaaaa tggaaacata gatgcagttg ttactaatga
     1201 agcagtttct ttaataaatg ttaaaaaata tgatggaata aaaatggcaa atactgaagt
     1261 tggtaaagat gtaacagaag gtatggcagc agcaatcaaa aaatctgaca ataacaaaga
     1321 ttttatagaa ttattaaaca aaaagataaa agaattacaa gatggtaaga agatagaaga
     1381 atttttaaat gaagcatcta ctgaagctgc ttcaaattag taagaaagtt atgtgggaga
     1441 tgaaattatg agtttagatt ttagtttttt aagtagattt gggacttctt ttttggaagg
     1501 aacaggtgtg acagtatcaa tttctcttgt ggcattatgc tttggattta taataggtat
     1561 aattatctgt atggcaaaaa tatcaaagag caaagtatta agagcaatat catcaatcta
     1621 tattgaggtt ttaagaggga caccattatt agtacagata tatatagtat ggtttggttt
     1681 acctcaatta ggaataagat tccctatgtt gtttggtata ccaagtgaat ttatagctag
     1741 tgcatttgca ttatcagtaa actctggtgc atacgtggca gagatactta gatcaggtat
     1801 acaatcagtt gataatggac aaatggaagc aagtagatca ttaggattaa attattggtc
     1861 aactatgaga tatataataa tacctcaagc tataaaaaat atattacctt cattagcaaa
     1921 tgagtttatt acacttgtaa aagaatcttc aataatatct gtaataggag ttgttgagat
     1981 aatgcgtact gctgatatag taaaaaatgc agcatttaga gcattagagc cattaatagt
     2041 agcagcagca atttactttg ttataacatt tactctatca agattagttg gattattaga
     2101 aaagaaacta tctgtgtcta actagatgag agcatgttta gcatttaggg aaaacataga
     2161 atagtaaaaa ggaaagtgat aatatgatta caataaaaaa tttaagtaaa tcttttggag
     2221 atttaaatgt attaaaaaat atagacttag aaatcgctaa aggcgaaata atggttatag
     2281 taggtccaag tggttctggt aaaagtacac ttcttagatg tatgaattta ctagaaatac
     2341 ctacaggtgg agaaataata tttgaaggaa aaaatttggt cgataaaaaa actaatattg
     2401 atgaggttag acaaaatata ggtatggtgt ttcaaaactt taatttattc ccacataaga
     2461 ctattttaga taatataaca ttagcaccaa ttaaattaaa aaagatgact aaggaagaag
     2521 cagaaaaaaa agcagaaatt ttgttgagta gagttggtct tttagataaa aaagattcat
     2581 atccatcaca attatctgga ggacaaaagc aaagaatagc aatagctaga gcacttgcta
     2641 tggaaccaga tatgatgttg tttgatgagc caacatctgc tcttgaccca gaaatggtaa
     2701 acgaagtttt ggatgttata aaagaacttg ctaaagaagg tatgacaatg gcaattgtaa
     2761 ctcatgagat gggatttgct aaggaagttg cagatagagt tatttttata gatggaggaa
     2821 gtatacttga agataatact ccagaagaag ttttcggaaa tccaaaacat gaaagaacaa
     2881 aagcattttt agcaaaagtg ctataatata taaaaaggat gttattgata ttagaaattc
     2941 aatacatcct tttttagtga tggttaatat taattttaaa attaaagtta tattaatatt
     3001 aactttattt ttacgatttt ttgcagaaaa aaaaagagct cggggtaagc tctttttttc
     3061 caccgaatta atttccgtta ctaatccgat ttttaataaa tataaaatat atccttatga
     3121 aagggtattg ggaatagata tattaactaa ctagggttac cagggggata accttaattt
     3181 attataacaa aatgcgacac aaaaatcaat attttttttg aaataaatta taaaagttat
     3241 ttttataaca agtaagctta taaatttaac ttttatagta a
//
LOCUS       DAEQJM010000152         3181 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.156, whole genome shotgun sequence.
ACCESSION   DAEQJM010000152 DAEQJM010000000
VERSION     DAEQJM010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3181
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.156"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(286..507)
                     /locus_tag="KRQ43_003644"
     CDS             complement(286..507)
                     /locus_tag="KRQ43_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HBH2743975.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            1087..1344
                     /locus_tag="KRQ43_003645"
     CDS             1087..1344
                     /locus_tag="KRQ43_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH2743976.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENNV"
     gene            1793..3031
                     /locus_tag="KRQ43_003646"
     CDS             1793..3031
                     /locus_tag="KRQ43_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH2743977.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISVLSDKGMTNKKNYFNHNHGIQKRNKSATKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         1314 a          288 c          479 g         1100 t
ORIGIN      
        1 tattagtatt ttaattgttg actctagtta ttgctgatat agaaaatatt taatttattt
       61 caattaatta gattaaagta gggtagcatt taaaatagct aacatgttta agttgaaata
      121 cgtttaatat attaattttt caaagcatta atatattaaa gttataacca aaattgaagt
      181 tataatctgc caaatctata gcgtattaag tgcgttatat aacttaatct tttatataaa
      241 gagttaattt ttttaatttg taaagcagag tacgtttaaa agatactatt tagataatga
      301 tgtactatct aattttaaaa tatctacaat agggttctct tgaagacttg ctattgcttc
      361 tgcaacagca taaacatctt catttaatgc ctctgctttt acatttgcaa atgatttact
      421 tttaacaact gccttaccct tatcatcaaa accagcatcc aattttagtt ttatactaga
      481 taaatttttt gttgaaacaa cttccataaa attacctcct aaaaatttaa tttcaaagat
      541 ttgtcgactt tctttgttag ctataatact atcatctaag ataatatcgg agttaaacag
      601 taatttctaa agattttttg tgtaaatttt tataggaaaa attttacttt tctgatgatg
      661 aaaaagttta caagttattt ttgaagatat gttcttagtg ttttgaaata gtatttgtat
      721 atattcatgc ttagttgaga tagttttgta tggattttca tatgtgtaga gttaaatgtt
      781 aggtaccaaa gtttatgtta aattaaatgt taaagcttat gttaaaaatt ttattaaatt
      841 taatctgtaa ataaaaaagt taaaagtcca atattaacat tttactttta aaccattaaa
      901 atctttatta aagctaacaa agttataagt tatgagaaat tttattaaag ttaatacaaa
      961 aattaatttt aaagctaaga aattttttat tagattcaat aaaactaata aatatagttt
     1021 agtcaataat gtattaaata aaaactttgt taagtctata aaaatatctt aaaggaggtg
     1081 taacttatga agataaaagt ggaggatata ccagttcaat ttcatgcaat ggtagaaata
     1141 atcggaattg ataagttcat agaggttgcc aagttgtatg gaggaacaaa tacttatata
     1201 cctacgtata aggggctttt tagatatgct agaaataggg atatagtaaa acaatttaat
     1261 ggagtcaacc ataatgaatt ggctattaga tataatatgt gtgtaagcaa tattaagcga
     1321 atactcaatg aaaataatgt ttaaacataa tgaaaatagc cttgttaaat gtaagagtaa
     1381 agacaaagaa gatgttttat aaagtttttt tagacaaatt aactaaattt actacttatt
     1441 aatttaaata cattgtatat tctataaaaa aatttgttaa atactggaga tatattgaga
     1501 atacaaagaa aatggtcgaa aatatttgtt ggctaaaaaa tagataaaat gatacaattg
     1561 cttgtataaa ggggaaaaat aaataaataa actatataaa taaagaaata gcaattaata
     1621 tgacataata tatttataaa attaagaata taaatagata ttttaaggga ttagttgtta
     1681 aattaggaaa tattaaaaaa atatatatat ttatatttaa actattttgt tatttatata
     1741 aaaatactta tctagttact agcaattatt agtagaaatg ggggaaatag agatgaataa
     1801 gggattttac aaattaaatt cagtggtatt gaactttgat attaagaatg atgttaacaa
     1861 gataagattt aatcattata taatgagaaa agaaaacata caaagacttc aaggaactct
     1921 gccaaacgga caattttata tgacagtgag aagagctgct acagatttac aactttctat
     1981 ttctactata agtaggcttg taaaagagtt tttggattta gggataataa gattagtgtc
     2041 taagggtgta aaaggtaatc gttctgtata tagttacgta agtatagagt ttaatggaag
     2101 tttatttgat gatagcaaat atatggaact tgactgtgta tgtaatgatg aatttattga
     2161 taatagtggc atagagtttg attgtgatag caaagataat tcttttaatg gagatataaa
     2221 tgtagaaact gtgcattgca ttaatgagta tttctctgat gatgatgtag agcataatta
     2281 taacaatttc cataataaag atactataaa ggataaagcc atttctaata ttagcactat
     2341 caaaaaatat attgatgaat cttttgatac aaataaatca gaaaattcta acttacaaca
     2401 ggagtcaata aatttcaact ttaatgatac atgcaatgaa atagataaaa gaacgaataa
     2461 tagtatagaa aataatcaaa ataaaaggcc tatgagattg agtgacatca gtgttttaag
     2521 tgataaaggt atgacaaata aaaagaatta ctttaatcat aatcatggta tacaaaaaag
     2581 gaataaatct gcaacaaaga aaaaagaatc cttaaataaa tttaataaaa aaaatataca
     2641 gcaaagcatt ataaatatgc taaataaaaa atcaggtaag aattttaaaa tcgattctcc
     2701 aataagcata aaacttatca atgaaaggct aaaggagggc tatgtcttag aagatttcta
     2761 taaagttatt gaggtaaaag tggctaagtg gaaaaatacc ataatggaaa tgtatataag
     2821 accagaaacc ttgtttagct ataagtttga atcctatgta aatgaaaaca tatctatgaa
     2881 aagtcaaagt aatgttcatc catgtaaaga aggcaatagt aatgatagca gtaattatat
     2941 acattctgat tatacaacat atgatggcag tgtgcgtgag agaaaaaaat atgagaatgt
     3001 aagatactgg aatcctatat gtgaaattta attagtttaa gaatgtattt atgataaata
     3061 agatattaat agagaatagt gagctatagc aaatgatata tcaatagttg gtagtaagtt
     3121 atattaagca agatattact atcaggtagt gaattatagt gaacgatata tcaataattg
     3181 g
//
LOCUS       DAEQJM010000153         3120 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.157, whole genome shotgun sequence.
ACCESSION   DAEQJM010000153 DAEQJM010000000
VERSION     DAEQJM010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3120
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.157"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..363
                     /locus_tag="KRQ43_003647"
     CDS             <1..363
                     /locus_tag="KRQ43_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2743978.1"
                     /translation="LMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGITL
                     FKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNISL
                     KKTNAKLVPKINQKKEVL"
     gene            364..1119
                     /locus_tag="KRQ43_003648"
     CDS             364..1119
                     /locus_tag="KRQ43_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH2743979.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNNLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKENLTVEEILEKFEYAV"
     gene            1216..2253
                     /locus_tag="KRQ43_003649"
     CDS             1216..2253
                     /locus_tag="KRQ43_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH2743980.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKKTDSKKQ
                     KNIGISQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISTSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
BASE COUNT         1204 a          402 c          468 g         1046 t
ORIGIN      
        1 cttatgattt caaacggact tatagcttta tctggtagtc ttatggctca gttcttggga
       61 ttctcagatg taaatatggg tataggaact ttagttcttg gaattgcctc tatcataatt
      121 ggtattacac tatttaagaa atttactttt atcaaagata ctactgcaat aattgttggc
      181 tcttttatat accaattcac tatatacttt gcaatgagtt taggaatgtt atcaactgac
      241 ttaaaactaa taactgccat agttataata gctttcctag ctactggtaa cttaaatatt
      301 tcactaaaaa aaacaaatgc aaagctagta ccaaaaataa atcagaaaaa agaggtgttg
      361 tagatgttac aaattaaaaa tctttcaaag agtttcccta atccatatgg tgaacctaat
      421 actatctttg aaaatttatc aatcgatata gaagatggtg aatttgtaag tatcataggt
      481 agtaatggaa ctggtaaatc tactttatta aatataatat ctgggcttat aaaagaatct
      541 tctggtcaaa ttactttaga tagtactact ataacaaatt tagctgagta taaaagaact
      601 caaatagtaa gtagagtttt tcaagaccca agccttggaa cttgtccttc tatgacggtt
      661 agagaaaatt tatctctagc acttaataaa gggaaattat tgaacttaaa aaaatgtctt
      721 cgtcataaaa cgaataattt ggaacactta cttgaaggaa tttctttgga cttaaaaaaa
      781 tatttagata ttaaagtaca atatctttca ggaggtcaaa gacaatcact atcactaatt
      841 atgtctagct tagcaagtcc taaggtctta ttactagacg aacatacagc agcacttgac
      901 ccaaaaacat caaatgaagt aatagagtta acagataaaa tcgtaagaga aaaaaatata
      961 actacactta tggttactca caacttgaaa cacgctcttc aatatggaga taggttgata
     1021 atgcttcata agggtgaagt tgtattagat gtaaaagata aagaaaaaga aaatttaaca
     1081 gttgaagaaa tcttagaaaa atttgaatat gcagtataag aaattaaaat cttagtttta
     1141 atcagaaata tttataatct atcatatgaa tatatgaaca aatataatta ttaaatttta
     1201 agggaggaaa ataaaatgat aaaaagtaaa aaaatattaa gtttaattat agcaggagta
     1261 cttggtgtat caatgcttac tggatgttct caaaatgatg gctccaatgc ttcaaatgaa
     1321 aataaaaaaa cagatagcaa aaaacaaaaa aatataggta ttagtcaatt agtggaacat
     1381 ccgtctctgg ataaagcaaa gaaaggattc atcaaagcac tcgaagataa aggctataaa
     1441 gatggagata atataaaaat agatttccaa aatgcacaaa atgatatgcc tactacacaa
     1501 agtattgcta gtaagtttgt atccgacaaa aaagatttga tatatgctat atctactcca
     1561 tctgcacaag cagcttataa tgctactaaa gatattccaa taataatgac tgctgttaca
     1621 gaccctgtag aagctggact tgttaaatct cttgaaaaac caggtggaaa tgtttctggt
     1681 acatctgatt atctttcaat tgataaaaca ttagaattgg ttaaaacatt gactccaaaa
     1741 gcaaagaaaa taggggttat atacaatact agtgaagtta attcaaaaat ccaggttgat
     1801 tctctacatg attatgctaa gaaaaataat tatgaagtag ttgaaaaagg aatcagcact
     1861 tcaagtgaag ttaaccaagc tatttctagt ttagttggca aaatagatgt tttatatgtc
     1921 cctactgaca atttaatagt ttcttctatg ccaatagttt ctaaagttgc taatgaaaac
     1981 aagattccta taatagcctc tgaagaaggt tctgtatctt ctggtgcttt agcttgttgt
     2041 ggaatagatt atgaaaaact aggttataag gctggagaac ttgctattga agtattagaa
     2101 ggaaaatctg ttggcgatat accagttact acattagatg aaactgaaat aataattaac
     2161 gaagatacac taaaagcact tgacatgcaa aagttatcag cagataatat aaagtatata
     2221 aagtcagatg aaaatgcaaa atctgcaaaa taaaacttat taatttcaaa aaataggtaa
     2281 tatgaagtag gtaatatgaa aactttatat aataagtact cttatccacc ctaacccttt
     2341 gaaaattgtg cttattgtag caatttgaat attgcatata aagttattca ttttccataa
     2401 aagtcgtcta tattgacgac tgattatgaa agttatataa ctttctaatc actacttgag
     2461 ctgtccaaaa gaattttaat attctccaga cagctttttt ttatgatatt tgattgatat
     2521 acatgtctag ttattccata tttagtaaat attttgataa aatttccaca ttcacttata
     2581 acttaggata acgttttttg caaacaatac attaatttaa aagtattctg agtatacatt
     2641 atttagtatt ttaattaaat ttagcagttg acttttatta ttgtataatt tataatttat
     2701 aacaagtcga gaatacatat aattttctga ctaattaaaa tattaaaagg gagagataat
     2761 tatgaatact ttattaaaca atagaaaata ttattattat tatagccact atttttaggg
     2821 tttgtaccta cgttttaaca tagatacaga ccccttaaga ctattaaaat tttgggattg
     2881 tatctatgtt ggctatattg tttataaagt tttcatttaa ctatataaga gccacataga
     2941 ttaaactatg tggcttattc gtgtttttac cacatagttt tgtacactat gtggtttttt
     3001 tatacacaaa attagcaaat aattaaaatt ataaaaatat tttcaaagga gtgttttatt
     3061 tatgtcaggt attatatctg taatgacgca aagtttaatt ttatcgatta tggcactggg
//
LOCUS       DAEQJM010000154         3082 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.158, whole genome shotgun sequence.
ACCESSION   DAEQJM010000154 DAEQJM010000000
VERSION     DAEQJM010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3082
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.158"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..153)
                     /locus_tag="KRQ43_003650"
     CDS             complement(<1..153)
                     /locus_tag="KRQ43_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2743981.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARY"
     gene            complement(327..1193)
                     /locus_tag="KRQ43_003651"
     CDS             complement(327..1193)
                     /locus_tag="KRQ43_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH2743982.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNVEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTREYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(1419..2288)
                     /locus_tag="KRQ43_003652"
     CDS             complement(1419..2288)
                     /locus_tag="KRQ43_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH2743983.1"
                     /translation="MDYKTIILNRKSVREYKNIDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNKSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(2794..3015)
                     /locus_tag="KRQ43_003653"
     CDS             complement(2794..3015)
                     /locus_tag="KRQ43_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743984.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
BASE COUNT         1025 a          533 c          307 g         1217 t
ORIGIN      
        1 gtatctagct atcttaaagg ctaagatgat agaaggatta tacctaccat tttctaatga
       61 acctatagtt tgtcttgata cttgcaaaat agaagcaagt tcttcttgtt ttatgcctct
      121 ttcttttctt atttcttcta atctattttt cacatctatc cccctttaat atctcaacta
      181 cggaaagtct actttccata attatacaac tatatttcat ttatgtaaag cttgctttcc
      241 atatttacaa aaaaataaca gactattttc agcctgtaat tttaaaattt catgttgttt
      301 attaaattta atgttattca ttaactttaa cttggtttct gaattggaat ccaaacttct
      361 gtagtataat caggagcatt gatatcgcca ttgggataaa gttcaatatc tggtaagtta
      421 gcatacacat acccagaact tggtaaccac tcagtaataa ttcttttttg caattcctgt
      481 attgccagag catttggcat tggagaaaca cattcaaata ctgcccatgt acctgatggt
      541 attaagtatt cacgagtatc ttctaataca ggcttatctg ttggtgcagc aatataataa
      601 tctaaaccct tactatttgt acacacacta actccaagca atccacaagg ttcgttattt
      661 attaactctg aaagtttatc aattgttcca ttttttatgc atttagccca taacttagga
      721 actttctcaa agcactcttc tacaatcatg ttcatacttt cttttatacc aacaatacga
      781 aaccctttct tttctacaat acgatattgc atttctacat ttccttttac ataaatgctt
      841 aatgtcatct taggatatgc ttttaaaaca acaccctttg ctctagctgc agatggagaa
      901 atgttatgta tattttgaaa agctctatta aaagatgttg gtgaatcgta accatacttc
      961 tcagatagtt ctaaaatttt gatgttactg ttctgaagtt caaatgcagc cttagtcata
     1021 cgtcttcgtc taatatattc agataatggt acttctgcaa tatatgaaaa cattctttga
     1081 aaatgaaagg ttgaacaaca tgcaattttt gctgcttctg cataatccac tccactttcg
     1141 agattttctt caatataagt aatagcttga tttaatttat ttatccattc catttgatat
     1201 tacctccaag caaattatac agtttaataa aataatatac ctctctattc atgcacaaaa
     1261 ttgtaagcat ttaaattcat aagtattttt caatcaatac aataaatata aaaattgtat
     1321 tatacaataa aaaagttcaa taacatttta ttataaaata ttattgaact ttttataaaa
     1381 attaatttaa gtgtagttaa attaagtatt aaactatctt atatattaca atatcctact
     1441 atcttatagt cttctggcac tttataatct ttgtctggag tacctaaatt ccattttaaa
     1501 tcaaacatag ttgcacttat tattgttgca aaataaagca taactatacc aatgtctatt
     1561 ttttcttcat ataaattagt atgaccatct tttctaacag ctaaaactac agtgcctcca
     1621 tcaactataa atctccatgg ttgtctattt aatgtagatg gagctaatct tgcatagtga
     1681 aatgcatcaa gaagtgctct ttcttctaag atttctatac ttgcaacatt tccccattcg
     1741 ttcatataaa caacatcttc tacacctagt ctagtagacc ccttatctgt tacaacttgc
     1801 atatcagatt ttgaataatt ttgcccagtt tttgtagcat ttaatacttt agcattactt
     1861 acattttctc catatccaat agctataatt cctgttacct ctttatctga attaattcca
     1921 agtttttctt ttaccttttt tccatcttca aaagtaaccc aacaagaacc aattccaagt
     1981 tctgttactt taaagattat actttctcct atgtaccctg aattttcaat gtaattatct
     2041 tttatgtcag ataatattat aatataactt ggagaatcta tcatatttcc tttgtaccct
     2101 gctactttat ctaaattatt aaaaacttca cttttattca taattcttac atcaacatct
     2161 atttctggaa ctagtttctt acaagattct gagtatttct taatttcact aagatattct
     2221 tctttaatat ctatgttctt atattctcta acagactttc tatttaatat gattgtttta
     2281 taatccataa ttttatcctc cccaaactag tattgtctta attatatacc cattaatata
     2341 ttattttact catttattta ataaataaag attacaattt tgtaattatt atttattaat
     2401 aatattccac ttttacatta ataatgacca gttgtgcaaa atccattgcc aaccaccaaa
     2461 taaaaacata ttataaaagt aatataaaat aacaaacaaa tcttaacaaa aaattaaact
     2521 ttttttacac gaaagaaggc ttcccgttgc cttctttatt tttataaaaa aataagctgt
     2581 ttctaaaatg atttcacatt tttgaaacag ccaagttatt ctataatgac aactataatt
     2641 tgaggatgtg agggagagtt gtcattataa atttagggta attatattat gttttaagct
     2701 agttcttcct atatttatat aatacatttt atatatgaat tttatatgag attggtataa
     2761 atgatatatg aaattacata tgtttatatt atattaaatt ttattattac attttccaca
     2821 acaatactca tatgtctcca cattatttgg aatatttaca aatacaaatt ctttacagtt
     2881 ctcacaatac tttaatatag atatagttcc acaagtgtaa cattcaaata ttacacaatc
     2941 ctcattttcc tctactattt caaacttttt actatgttca ccacactctg ggcacttgtg
     3001 attatttaca ttcataaata ctcctcctta ttagtatagt tacatttcaa aaacttaatt
     3061 aatgtattct atattactta tt
//
LOCUS       DAEQJM010000155         3062 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.159, whole genome shotgun sequence.
ACCESSION   DAEQJM010000155 DAEQJM010000000
VERSION     DAEQJM010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3062
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.159"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(145..666)
                     /locus_tag="KRQ43_003654"
     CDS             complement(145..666)
                     /locus_tag="KRQ43_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH2743985.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENIIIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
     gene            794..2158
                     /locus_tag="KRQ43_003655"
     CDS             794..2158
                     /locus_tag="KRQ43_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH2743986.1"
                     /translation="MKESNKKIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDKLHIAIKTSILWTTIFCVVLGL
                     ILVLFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            2347..3024
                     /locus_tag="KRQ43_003656"
     CDS             2347..3024
                     /locus_tag="KRQ43_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH2743987.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSDYKKGNPVH
                     CGDSDCIGILIIKSGTIRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQINSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
BASE COUNT          959 a          437 c          496 g         1170 t
ORIGIN      
        1 aaaagtttaa cattctccct caattaagtg agctttattt taaatatact tttcagttta
       61 tatcatttgt ttcatttttt ctaatatctc attattaaat atgctggttt ttgtttaatg
      121 attattaagt tagcttctct aattctaatt ccccatatta tcttttaaag aatttatcca
      181 ggtttccaat gcttgtgcta gcaccaactg ttgctccaac actgcttttg ctgtctctgg
      241 tacttctgtc tttataatta tattttcctc aatagttttc tttaactctt gaacattctc
      301 ttcaatatta ttgagacata atttctgttt ttctggtgta aggctattta aatttactat
      361 aacagcatta aaatctaaaa gaatatttat tggtttgcta gatgtatcaa acattaaatc
      421 taaaaaatgt gtctcaccta attcagttaa tgaataaact gctttttctg gcatttttcc
      481 attcttcaca gttttacttt caatatatcc cttttgttct aattgaatta cttttttata
      541 aattgatggt gtacttattt taacccaacg tgatatattc ctgtattcca ctgccttttg
      601 aatatcataa gcactcttgg gttgttgctt tactattccc aatacaatta aatctattgt
      661 agccataaaa atcatctcct ttagttttct tactattgac aaatactata aattatagta
      721 ctattttcca tacttactat aatttatagt attataattt agacttaatg tcaatagaag
      781 aggagtgtta agtatgaaag aaagtaacaa aaaaattgaa ttattagggt ctgccccaat
      841 ctcaaaagca ttgttatcta tgggattacc taccatgata ggtatgatga taactgcatt
      901 atacaatttg gttgatgcat actttgtggg tggacttgga acaagtcaaa tgggagctat
      961 atccgttgca tttccattag gtcagcttgt tgtgggatta ggattattgt ttggaaatgg
     1021 agctgcttca tatattgcca gacttttagg ccatggtgat aatgaaaaag caggaaaagt
     1081 ggtaagtaca tctatttaca gtagtattat agtgggtaca ttagttatta ttgtgattat
     1141 gatttttctc aatccaattt taaaattgtt aggagctaca aaaagtatta tgccttatgc
     1201 aatatcttat gctagcattt atgtcgtgtc atctattttt aatatattca atgtcactat
     1261 gactaatatt gtcacaagtg aaggagctgc taaaacaact atgtgtgcta tgttattagg
     1321 tgctttgctt aatatgattt tagacccgat attcatttat acttttggtc tgggggtaag
     1381 gggtgcttct attgcaacag ctatctcaca gattgcttca acacttgttt atgtaggata
     1441 tattttaagc aagaaaagta tatttagttt tagaattaac gaatgctgtt tttcaaaaga
     1501 aattttttca gaaatcctaa aaattggcat acctacatta atatttcaat tattgactag
     1561 tcttgccatt acattaacta atatggaggc tacaaagtat ggtgattctg tgatagctgg
     1621 aatgggtgct gtaacacgaa taacatcttt aggtagtctt gttgtatttg gttttataaa
     1681 aggtttccaa ccaattgctg gttataattt tggttcgaag aactacgata aattacatat
     1741 agcaataaaa acttccatat tatggactac aatattttgt gtagtgcttg gtcttatatt
     1801 ggtgcttttc ccaaaatcta taatttcaca atttacaagt ggtgacattc tattaataga
     1861 aaatggtagt aaagctctta gggcaaatgg gttttcattt atgctatttg gattctatac
     1921 agtgtattct acattattcc tagcactagg aaaagcaaag gaaggtggat ttttaggtat
     1981 gtgtagacaa ggcgtctgtt ttatccctat aattttgatt attcctgtat tctatgggtt
     2041 aaatggtatc ttatatgcac aaccaatagc tgatttgatg gctgctataa ttgctggttt
     2101 tatgtctata aggttacata aggaacttaa tcttttaaaa ataaacggta tgcattagtt
     2161 atacaaacct actatcatca aaacatatta ctttctcatt aatagcaaga atatatatta
     2221 tcatattttt tctacataaa tcatactatt actatctgac taaataatcc tcttaacaaa
     2281 ctacttgtca atttatctat tcacttgtat catgggatta taacaattta agaaaggaga
     2341 tattgtatga tttcacaaaa tgaaattgat atacttacac atagcttgcc tttttgggat
     2401 aaacttactg acttacaaaa agaattatta atttcttcag caaatacctc ggattacaaa
     2461 aaagggaatc cagtacattg tggtgatagt gactgtattg gtattttgat tataaagtct
     2521 ggaacaatac gtacatacat actttcagat gaaggtcgag aggttacact gttccgactt
     2581 gatgatggag atgtatgtat tttatcagct tcctgtattc taaaaacaat aacttttgat
     2641 gtctatgtag atgctgaaac ggactgcgat attatacaga ttaattcctc tgtttttgca
     2701 aaattatcta cagaaaatat tcatgcagag ttattttcat ataaattagc taccgaacgt
     2761 ttttctgatg ttatgtgggc tatgcaacaa attcttttta tgagttttga taagcgtttg
     2821 gcatcttttt taattgatga gatagctaaa aatggcagta gcactataaa tatgactcat
     2881 gagcaaattg ctaagtatat gggtagtgcc agagaagttg tatcgagaat gttgaaatat
     2941 tttgctagag aaggtattgt gtctttatct cgtggtggta taaaagtatt ggataaggat
     3001 aaacttcgtt ctttgacact gtaaaagtgt gtctcaaaat gaacttttta gttcatgagg
     3061 ca
//
LOCUS       DAEQJM010000156         2845 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.160, whole genome shotgun sequence.
ACCESSION   DAEQJM010000156 DAEQJM010000000
VERSION     DAEQJM010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2845
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.160"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..1389
                     /locus_tag="KRQ43_003657"
     CDS             <1..1389
                     /locus_tag="KRQ43_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH2743988.1"
                     /translation="VLISGFIGKIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRW
                     IFSIHEITLNTENFKRARKESVNLIKRKIIRTIIYSLILSLVVAIIGYAIYHSGIIFI
                     GIWTKYCTDMEFLKNVFINRCIAFEEYFRLILSIFIFILDIGFISATYYQYKGVNISK
                     NNIKKEKKSISKIVFNLVLILLISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEM
                     APENTLAAIEEASNAKADYAEIDVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEV
                     KTYDAGSFYYYGKGYYDEKFVGEKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDIVKK
                     VVQLIKENNFENQCIVASMDKTILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGI
                     ESTFVNKTVVEKIHKMNKKIFVWTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKK
                     NGFISQVSDYLF"
     gene            1711..2295
                     /locus_tag="KRQ43_003658"
     CDS             1711..2295
                     /locus_tag="KRQ43_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH2743989.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKDKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNVKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         1132 a          256 c          441 g         1016 t
ORIGIN      
        1 gttttaattt cagggtttat aggaaaaata caaataccag agtacatatt agattatata
       61 aagtctgata taattttaaa tataatctat atgatttttc ttttaataat ctatatttcg
      121 gttattagat ggatttttag cattcatgag ataactttaa atacagaaaa ttttaaaaga
      181 gcaagaaaag aaagtgttaa tcttataaag agaaagatta taagaacaat tatttattca
      241 ttaatattat ctttagtagt agctattatt ggatatgcga tttatcatag tggaattata
      301 tttataggca tatggactaa atattgtact gatatggaat ttttgaagaa tgtatttata
      361 aatagatgta ttgcatttga agaatatttt agattgattt tatcaatatt catttttata
      421 ttggacattg gatttatctc agcaacttat tatcaatata aaggagtaaa tatttctaaa
      481 aataatatta aaaaagagaa aaaatctata tcaaaaattg tttttaattt agtattaata
      541 ttattgattt cttatataga gtcagttgca ttttcttcac atataaatgg catgtttaat
      601 acgtcatttt cattttatac aacagcaatt gctcatagag caggagctga aatggctcca
      661 gagaatactt tggcagcaat agaagaagct tcaaatgcta aagctgatta tgcagaaata
      721 gatgttcaag aaactaaaga tggagaactt attgtacttc atgattcaaa ctttaagaga
      781 actacaggag tagataaaaa tgtttgggat gtaaattata atgaagtaaa gacatatgat
      841 gcgggaagct tttattatta tggaaaaggt tattatgatg aaaagtttgt tggggaaaag
      901 ataccaacac tcaaagaaat gataaaatat tctaaaggta aggtgaaatt attaatagaa
      961 ataaaactta atggacatga aaagggagac atagtaaaaa aagttgttca gttaattaaa
     1021 gaaaataatt ttgaaaatca atgtatagtt gcatctatgg ataaaactat attacaaaaa
     1081 gtaaaaaaac tggatgagaa tttactgaca tgctatttta tggcaattgc atatggtgat
     1141 ttttcaaagt taaattatgt tgatatatat ggaattgaat caacttttgt taataaaaca
     1201 gtagtagaaa agattcataa aatgaacaaa aaaatcttcg tttggactgt taatagtgac
     1261 agtttaattg agaaaatgct tgacctaaat gtagatagta ttattacaga taatccatac
     1321 cttatagaga gtgcaattta ttggaagaaa aatggattta ttagtcaagt gtcagattat
     1381 ttattttaaa tattctataa ttgtattatc cagtaaaaga gatattatta aaatcaataa
     1441 tatctctttt taacataaat aaggttgtta aattaaggtt attcttataa aaattgtgct
     1501 tatcagctat aaacaaggaa taaaagtgaa aaaattgctc tgagattatt acagttaaaa
     1561 gagttttaag atgacagaga gatagattgt caactgtata tttaataaat cttgttattt
     1621 attaaatttt atataagtaa aatatataaa ttaataaatc ttatgctaga atatatatga
     1681 aaaacaatat aaatttggag gattaaaaac atgacagagc gagaaaaaat gttggcagga
     1741 gaactttacg attgtggtga tattgagttg ttaactcaat ggcataaagc aaaagaccta
     1801 gtaagagatt ataaccaaac agattcctcg gatttggaaa aaaaagaaaa aatattaaat
     1861 gaattacttg gtggtaagga taaaaactta tggattactg caccgtatta tgtagattat
     1921 ggaaataata tttattttgg aaataattgt gaagtcaata tgaattgtac gtttttagat
     1981 gataataaaa ttatcattgg ggataatgca ctaatcgcac caaacgtaca aatatatact
     2041 gcatttcatc caactaatgc tggtgataga tttggtaatg tcaaagaaga tggttcattt
     2101 gaattttgta aaactcaaac agctccagtt actattggag ataatgtttg gattggcggg
     2161 ggtgctatta tcatgccagg tgttactatt ggagataatg tagttatagg tgcaggaagt
     2221 attgttacaa aagatattcc aagtaatatg attgcatacg gaaatccatg ccgtattatt
     2281 cgagaaaaca aataaagtta aattttcttg caaaatctca aaaaacacct ttcttacttt
     2341 atacataggg tattttccaa tactttcaca tccatattca tttgttaaat ttttgtggaa
     2401 tgtagttttt atcacttcta tcttacattt ccaccatttt ttataaaagt cattccttta
     2461 tagatttatt tataatagta tatattctat ttgatgtttg aataagcact tatttttaag
     2521 taaaatacta acttttaggt tagtattttg ctatagtatg atgattaagt aagaataaaa
     2581 tactataata cataaagctt aataaatata atttttattt tacttagata ttttcttttg
     2641 attagtaatc aaaagtggtt ataatttttt taattaataa gagtaatatt tattttatga
     2701 aagaggatta tattaatata tatttaaata ggaaaaattg taaaaagcat aaaaataata
     2761 taattaatta atgagataaa agtggataaa aatattggga gtttaatttt tgtgaaatta
     2821 aaaatattaa agctaatcta caaat
//
LOCUS       DAEQJM010000157         2636 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.161, whole genome shotgun sequence.
ACCESSION   DAEQJM010000157 DAEQJM010000000
VERSION     DAEQJM010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2636
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.161"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            459..938
                     /locus_tag="KRQ43_003659"
     CDS             459..938
                     /locus_tag="KRQ43_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH2743990.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRTLLKTKLENTEVII"
     gene            935..1714
                     /locus_tag="KRQ43_003660"
     CDS             935..1714
                     /locus_tag="KRQ43_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743991.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKALDKENNVLGKSKALSFEYKNGNDEISLDTANNVLEKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(1964..2464)
                     /locus_tag="KRQ43_003661"
     CDS             complement(1964..2464)
                     /locus_tag="KRQ43_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH2743992.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNTINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
BASE COUNT         1037 a          359 c          317 g          923 t
ORIGIN      
        1 tctatctaaa ataatgacat ttctaactct tgattctcat ttaagtttca ttgttttttc
       61 ttaaaagcct acttttagtc aaaataccgt tatctttagt cattaattaa aaaacttatt
      121 ttaaatctat acatgaagta aataatccaa aagcattatt ttctaactac tcaacatcaa
      181 atacttacta ttttataatt acttaatata aacacttact ataaaactaa atatataaat
      241 ggcttctaaa gtttaatata tctacatggc tttatatatg aggggaaaat actagaaaaa
      301 aatatattat agaatatttg tatagaatag gcaaaacttt caaacttaaa tttatcaaat
      361 aatcataaaa aaagtgaacc atctatagta aaattttatc taataagtga aaggcaaaaa
      421 agtagcgcta cgatttgcat agaagggaag gaactcagtt ggataaaact acatttacaa
      481 acaatatact tgaatcagaa cagactttgt atcgagtatc taagtctatt ctaggaaacg
      541 accaagactg tgaagatgcc gtcaacaatg ctattttaaa agcatatgaa aagttggatt
      601 ctcttaagga agaacaatac tttaaaacat ggctgattag aatagtcata aatgaatgta
      661 attcattaag acgcaaacga ttaaaatctc tatcatttga agatgtcttc aaaaacaaaa
      721 aaattgatga aaaagatgac tatagcgatt tgtatactgc tattcaaagt ctacctaaaa
      781 aaattaaaat tccaatagtc ctttactata ttgaaggtta ttcagtagat gaggttaagg
      841 aaatattaga tatacctcaa ggaactgtaa aaagtagatt atcaagagga agaacattat
      901 taaaaactaa attagaaaac acggaggtaa tcatatgaat aaaaatatat taaataattc
      961 gtttccagaa gttccagaaa gttttcataa tagtttaagt aaaacactaa atagtttacc
     1021 agaaagagag gaaaattata aaatgattaa taataaaaca cacaaattac catttagaaa
     1081 aggcttagtt gcaactttag ccattacttt gatattgagc acaacagccc ttgcagtagg
     1141 acatatatat agtttagttg gaaaatcaag tactaaggct acctatacat ctatcccaac
     1201 tacagaacaa gtaaaaaaag actttaactt tacccctaat atagtttctg aatttagtaa
     1261 tggatataaa tttaaaggag catatactgt aaataaaaaa gcacttgaca aagaaaataa
     1321 tgttttagga aaatcaaaag cacttagttt tgaatataaa aatggcaatg atgaaatatc
     1381 tcttgacaca gcaaataatg tacttgagaa gagttctgac aatctaaaag ttgtagatac
     1441 ttacaaagat attaatattt cttatgaagc attcgcacaa aagtttgtac cagaaggtta
     1501 taaaatgaca gaacaggata aaattgatga aaaatcaggc aaatacacat ttagtgtagg
     1561 gccaaataat gaatcagaca aagttgaagt taatgaattt aagtttttga catggaaaca
     1621 agatggagtt tactattctt ttacagttca agactcaaat ttatctatga atgacttagt
     1681 taaaatggct catgaagtaa tagatgcaaa ataaacataa gtaataataa gttgtttatg
     1741 agtttattat ttatgacttt aattttttta ttagtaaaca tggttgtatc ttccatcttt
     1801 atattttctt taaatttaat atataaaatt ttagatattt agctaccttc aaaagaacca
     1861 ttattaaaaa gcccttaaaa atatttcttt tatatggaat tttaagggct ttaactttat
     1921 tttatacaag tgtatatgga attttaaaga ctttaacttt attttatata agtgtaagct
     1981 ccatttgaat tacttcttct tttacaggtc tatcattcca tgtaaaacca ctagatattg
     2041 tatttacctc tacaaaccct aaagatttat aaacatgaat agctctacta ttacttttaa
     2101 atacatcaag ctcaattttt tcatacccat attcttttga taaatcaata atttgtttta
     2161 aaagactact tccgatacct ttttccctat actctttaag aatacccatg cctaaataac
     2221 caactttttc agttttaggt aaaacgtcac accaaccaat acagttatct gattctaaat
     2281 caattataaa cagttgtggt aagtttttat ttatagtatt ttttataaat tcaactgttt
     2341 cttcaaaagg aaaggcttca tccatagcta gatatttcct ctcttttgct attttatcaa
     2401 aagtttgcca atacgaataa atatactttt cttctgcctt tataaatttt attccttcta
     2461 tcaacttaac atttctcctt tttaatttat gattgtagtt aacttatttt atatgattct
     2521 agtttataat gctatataaa ttactatata ttagcttaaa atatctttgt atatttctat
     2581 aaaattaaaa ccaatatatc tatctcttgt atctctatta aaataatttt taatag
//
LOCUS       DAEQJM010000158         2618 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.162, whole genome shotgun sequence.
ACCESSION   DAEQJM010000158 DAEQJM010000000
VERSION     DAEQJM010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2618
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.162"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            228..1529
                     /locus_tag="KRQ43_003662"
     CDS             228..1529
                     /locus_tag="KRQ43_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH2743993.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1605..1880
                     /locus_tag="KRQ43_003663"
     CDS             1605..1880
                     /locus_tag="KRQ43_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH2743994.1"
                     /translation="MLELTKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
BASE COUNT         1067 a          208 c          524 g          819 t
ORIGIN      
        1 tgaacaatgt attaataatt ggtagtaagt tatatcaaat aagatattgc tattatgtag
       61 taaattatat gtatcagaat aaatagtata ttaataattt gtagtatatc atgacgaata
      121 atatagtcat aacaaatagt gagtcataac aaataatgta tttataattg ataatgtatt
      181 taaaaatcaa aatataaaaa cttataagga aagagagatt aatttatatg ggtaaatcaa
      241 aagatgttga aatagagaag tctattttag gcacaattct tttagacaat aaattaagct
      301 ataagctaga tgaattaaat gaaaacatgt ttatgaatga tatatgtctt gagatattta
      361 aaattatgaa agaacttaaa aaagaaaaca tagtgattga tgtggccact gtgaaatcaa
      421 agatagatag aaaatctcta gcaataaaaa cgagtgatgt gactaatcta attacttggg
      481 gtcagaattt tggtcttgat ggtcatatta aaattttaaa agaaaattta gctagaagaa
      541 gcataaatca aaactgccaa aaccttttac acagcctaaa ccttggagaa aatatcgata
      601 cttgtattta caaatttgaa agtaatataa aggagatttt ggacaaggat acttatgaaa
      661 atgatgatgt aaatagtata gcagggaagg tgcttgattt tttagaaaac aaaaaagata
      721 ttggatttaa atttggtata aaattacttg atactactat aggaggtctt tttaaaggag
      781 agctaaccac aatagcagct aaatcggggg ttgggaaaac tgctttggca cttcaaataa
      841 tgttaaattc atttaagcaa ggtaaaaaaa ctttatttat aagtagagaa atgaccagtg
      901 agcaagtatt tatgagaaat atatgcagag taactggtgt aagtacaagg aatatgaaat
      961 ctaaagaaat agatgaaaat gattggaaac ttattgtaaa tgctataggt gatttaagcg
     1021 aaaataactt aatttatatt aatgataaga tagatacaat tagtgcaatt agaaagagga
     1081 taaggcaggt aaagccagat ttattaatag tggattatgt gcaactcctt acatctcaga
     1141 aaagcatgga taagagagaa agggaggtag ctactttttc gagagaactt aaaaatatga
     1201 ctttagattt taatatacct gtaatccaat taagtcagtt aaatgatgaa atgaaagatt
     1261 caagacctta tggagataga cctatgaggg atagcaaagc catctaccac gatagcaaca
     1321 atgtggttta tatacatcaa ttaaagggga gtgattatga agaagcagtg agagatattg
     1381 gagaaagtga ggaggcagtt agagcatcag aatacagggg aattaagatg gttgatttaa
     1441 tagttgcgaa gtgtagagat ggacagacta ggcataagca tttttgttac tttggggata
     1501 agttacattt tcaagaacta aattattagg tcaataaagt agtaataaca agcttattaa
     1561 aagtcaggaa atagcaaata gattataaaa tatgaggtga aaatatgttg gaattaacga
     1621 aaattataga attacttgaa gaacacaaga tagaagtaag tattccaaag gagttacata
     1681 agtatagttt attggaatac cttgaattgt gtcaacaaag tgggggaaca tatttttata
     1741 ttaaaacact ggaaggggca ttaaaagagg ctagaaatga gcttatgatt aaattgttta
     1801 atgggaaaaa ttatatggaa ttagcgagga tgtttgaaat gagtgttatt aatgtcaggc
     1861 atattgttag aaaaaaatag atatttttgg agaatacaag tgtgatatac ttctgaaata
     1921 gaagttatta tagttgaaat aaaattgtgg ctaatttgtg tataagttta agattataga
     1981 ggagtataag tgtgattaac agcatgattt tgtgaataaa attgatgata tatatgagtt
     2041 aaatgtgtga ttaataaggt aaggttgtgt ataagattat gagtatttaa aaggaggggc
     2101 tataattaat agtgtagagt tgtatgtttg cttaagatta tataataatt taatagatta
     2161 aactatacga ataaggtaaa atcgtgtgtt tagttaaagc ttattataaa atcttgatat
     2221 gcgattaatg atgtaatatg tgaataaagt taagattata atagatttaa cctgtggcta
     2281 atagaataaa attgtgaata aagttaagat tataataggt ttaacctgtg attaatagag
     2341 taagagtgta aatagagata aacttcaatg tgggtttaac ttgtggttaa tagagtaagg
     2401 tgtaactaaa gataaacttc aatatgggtt taacttgtga ttaatagagt aaggtgcaac
     2461 taaagataaa cttcaatatg agcttaacct atgattgata gagtaagaat gtaaatagag
     2521 ataaacttca atatgggctt aacttgtggt taatagagta agagtgtaaa tagagataaa
     2581 cttcaatatg ggtttaactt gtggttaata gagtaaga
//
LOCUS       DAEQJM010000159         2434 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.163, whole genome shotgun sequence.
ACCESSION   DAEQJM010000159 DAEQJM010000000
VERSION     DAEQJM010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2434
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.163"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..1578)
                     /locus_tag="KRQ43_003664"
     CDS             complement(<1..1578)
                     /locus_tag="KRQ43_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBH2743995.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
BASE COUNT          822 a          419 c          222 g          971 t
ORIGIN      
        1 tatatccaac aactctttca ttgttaatga aatgttactt attaaatccg tagcatttac
       61 cgtatacatt gctttgctca atttatctcc tatatagcca tgtatatatg ctccactaac
      121 tgtagcttcc aatatatcca taccttgacc tataaatgaa gtaatcattc caagcaaaca
      181 atcacccatt ccaccagttg ccatacagct atttcctgta ggatttatat atgttttttt
      241 accatctgtt atgacagttt gataaccttt taaaagcacc accagattat atttttgagc
      301 aaattctttt gcaacatcta ctctatgttc tcttatatac ccaattgaat ctcctgtcaa
      361 cctggccatt tctcccaaat gaggtgtaat tacaaatcta tttttccatt ctaaaaactt
      421 ataacatctg tccttcataa cgttcaatcc atctgcatct aatactattg ggcaattaga
      481 attttctact atcttaagta atttatcaaa tgtttgacta ttatctccca tacctggacc
      541 aaaaccaatt gcatcactag aattaagtaa tttatttaat ctttcttctt caaaatttaa
      601 agtcattgct tctgtaagtc taatagatac cttttcttgc acatcttcac tactaattaa
      661 tgttacaagt ccactcccac tcttaacagc agattcagtt gctatgaaac ttgcaccata
      721 aaatcctttt gaacctgcaa ctatagatac ttttccaaaa tcacttttaa aaccatgctt
      781 atctcttctt ctaatattat tttttacaaa agtcttatca gttatgaact cttcatcatg
      841 gtattttctt gtaataaaat ctggaacacc tatcttttct acaactacat cacctataag
      901 tgtgctagtg tcatagttta gaaaacctct tttataaaac tcaaagctaa tcgttttgtt
      961 tgctctaata caagttccta atacatttcc attatcgcta tctatacctg aaggaatatc
     1021 tatagaatat gtatttttgc tattatcgtt tactatgtca ataacttctt taaaaatacc
     1081 agttatatca cgttttaatc cagtcccaaa tatagcatct actacaacat cacttttaga
     1141 tactctatct ttaaaaattg ttaaattttt attttttata atattttgtt tctcaacttt
     1201 aataatttta tctacttcat tttcatctcc ataatttttt tcacttaaat catttttatt
     1261 aatatttata atattaattc ccatatttaa aagtacattg taatttattt tagagcattc
     1321 acttagtttt tcaagattac ctactaaaaa tacgtttact tcttttccat atgtatttag
     1381 atgtcttgct attccaagac catctcctcc attatttcca acaccacata caactgtata
     1441 actattatac atgtctatat ccatattttt cattgcagat ataaccgcat tttccatcaa
     1501 tacaatcatt ggaatcccta cttcttctac acatgcagta tcaacatttc tgcttaattt
     1561 agatgtacct attagcataa attatcactc ctataaagtt aaagacttct taaatactta
     1621 ccaaaaatat ctattgaaat cttttaatcc cataaatatc ataaataaaa tcactaaaac
     1681 taagagtttt gaaataattt aaaataacaa aaaattttga attaaaacaa ttatttaatt
     1741 tattatacca tataatttaa gttattatgt tgatttaaaa cctatttaca ctaattatct
     1801 aaatatctct ttatttttat aatcttttat gacttattta tatttttcat ttttataaaa
     1861 aaacaataat taagaatata actatattct acatgtaaaa atttttttat ttaaactcaa
     1921 ttttctgata acttgataat ttttcaaaat ttatagttga cttttatttt ttactgtatt
     1981 aaactaatta ctatacaaaa cagaaaacaa aattttcaaa attattaaat taaaaggaga
     2041 ggtaaatatg aagactttat taaacaaaca agtacgattt tttagtagcc aatttagtta
     2101 gggtttgtac ctaagttaag acaaattgtc ataacataga tacaagcccc ttaggattat
     2161 gatttttaag gattgtatct atgttggcta tagtaattgt tgttaaagtt tttattttat
     2221 catcataata tagagccaca tggattatac tgtgtggctt attcgaattt ttgccataca
     2281 gttatatata ctgtgtggtt tttttatatc aaaatcattt tttaaaacca aatttaaaaa
     2341 accatttaaa atattttcaa aggggtgttt tatttatgtc aggtattata tctgtaatga
     2401 cgcaaagttt aattttatcg attatggcac tggg
//
LOCUS       DAEQJM010000160         2401 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.164, whole genome shotgun sequence.
ACCESSION   DAEQJM010000160 DAEQJM010000000
VERSION     DAEQJM010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2401
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.164"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(84..995)
                     /locus_tag="KRQ43_003665"
     CDS             complement(84..995)
                     /locus_tag="KRQ43_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH2743996.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SVGFPLYSKVGAAGGYHVLKERILPPITFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENMRRKLVFWTPDRHCSTPLLKELFNIVMNEFTIKIEYSSK
                     QKNSIRTIVPIGLYAMNGLWYCPAYCIKSESVKEFRADRIVKILSIENLSNKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKK"
     gene            1106..1573
                     /locus_tag="KRQ43_003666"
     CDS             1106..1573
                     /locus_tag="KRQ43_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743997.1"
                     /translation="MENDTIKADDILNYCLSNLDDVVLMDSWGERAIYYNPNGVLKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIEESYNFAKQKFKKRKNK"
     gene            complement(1741..2340)
                     /locus_tag="KRQ43_003667"
     CDS             complement(1741..2340)
                     /locus_tag="KRQ43_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743998.1"
                     /translation="MKLKRTLFVGLALVLAIGITACARDNEKPNENAGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKRMNDDLIAEGERLVKDIDERIEKLDKVSDEDMKKGQN
                     DFMKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT          807 a          400 c          281 g          913 t
ORIGIN      
        1 ttatcctatc tctacatata agtttcccta tatgctgact aatttagcta ctaactcatg
       61 actaaagtca caagtgtgcg tagctatttt ttaatcaaat gtttaagttc tataggttct
      121 attattgtag cattttttcc aaaagttaaa aaatattcag ccacccaatt aagtgtagat
      181 tttggtatat acatatctat gtatccaccc ttagacaaaa ttttcaatcc tcttgccaac
      241 aaaaattctg tttcacaacg ttttactccc tcatctgtca gattaatttt aatatgataa
      301 tctgtaccta cttccatatt cttaagataa tcatgtatag aagataaaac cttatatttc
      361 ttatttgata agttttctat actcaaaatc ttcacaattc tgtctgcacg aaattcctta
      421 acagattctg attttataca gtaagctgga caataccaaa gtccattcat agcatacaaa
      481 ccaataggaa caatggtacg tatactattt ttttgctttg atgaatattc aattttaatt
      541 gtaaattcat tcattactat attaaacaat tccttcaata atggtgttga gcaatgccta
      601 tctggtgtcc aaaaaacaag tttacgtctc atattctcaa tattatattg aatatcattt
      661 ggtatacaat ttaaaaattt ctttaaaaca gaaatagttt cttgctcaaa tggtaaatca
      721 ttataatact ctagtgactg atatgcaaag aatatagatt ttacctcact ctctgaaaat
      781 gtaattggtg gaagtatacg ttctttaagt acatgatatc ctccagccgc tccaactttt
      841 gaatatagtg gaaatccaac actttccaat acctgtaaat ctcttagtat agtacgtttt
      901 gatacagaaa attcttctgc tagctctccc gctgtaaaac ttctttttgc atttattgtt
      961 atcatcagtt caattaaacg ctcagctctt gacatattca tactcctaat ttaaatatag
     1021 tgacaataat tgtcaccatt atatgataag atattcttgc atctaaagca ataataatat
     1081 taaagaaaga agggattgat attttatgga aaatgatact attaaggctg atgatattct
     1141 caattattgt ctatcaaact tagatgatgt tgtactaatg gatagttggg gggaacgagc
     1201 aatttactac aatcctaatg gtgttttaaa gcgaggggta tatgttctta ccattaaaga
     1261 aaaagacagt aatcatgata aaggttcgtt ggttagtcgt ccaaatgtat accgtgtgaa
     1321 tataggatta aaaaaagaaa cttttattga aatgtttgga tatattccaa agcgtccagg
     1381 tgtagggcaa atagttgata tggattttga ttttacaaaa ttggacacaa tcatgccaca
     1441 tcctatctac tcatggatgg gatggatatg cgtcctaagc cctactgaaa agacatttga
     1501 gaactttaaa actttaatag aagaatctta caattttgca aaacaaaaat ttaaaaagag
     1561 aaaaaacaag taaaaacata aaaaaataac ctctaaataa actataatga aaatatgagg
     1621 ttacaagata aaaattagta tcttgataac atacaaaaaa gcgaagccaa aaaatatatt
     1681 aattacaagg cttcgctata tttcaaatat ttatttctaa ctttaaaact atttactcta
     1741 ttatttttta ttatttcctg ttattcccaa tctatcattc atatctttta tcatttttct
     1801 aaaaccacta ccaatatcgt ttccaacatc ttcagttcca tgaactagtt tcataaaatc
     1861 attttgacct tttttcatat cttcatcaga taccttatct aatttttcta ttctctcatc
     1921 tatatctttt actaatcttt ccccttcagc tattaggtca tcattcattc tctttaactc
     1981 tgtatcttct gttttaccgt cttttttaag agatgttaca aatgattgta ttttatctct
     2041 actatcttta tatgcagcct ttacatcact tagatatttt tcatttcctg gatattcttt
     2101 atctttaaac tgattgttta tactttctgg agtatcataa atagaatatc tatttagacc
     2161 tgctatataa tcattataac ttgttgaata ataattcata tatccttcat tattatttac
     2221 agattcatta ggattttttc ctgcattttc atttggtttt tcattatccc tagcacatgc
     2281 agttattcct atagctaata ctaatgctaa tcctacaaat aaagttcttt ttaatttcat
     2341 ttttattacc ctcctagatg ttttgtacta caaaaaattt taataatttt ctttcttaat
     2401 t
//
LOCUS       DAEQJM010000161         2400 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.165, whole genome shotgun sequence.
ACCESSION   DAEQJM010000161 DAEQJM010000000
VERSION     DAEQJM010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.165"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            283..681
                     /locus_tag="KRQ43_003668"
     CDS             283..681
                     /locus_tag="KRQ43_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2743999.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRRNARRHNIL
                     TKLVLSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    1117..1380
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1531..2082
                     /locus_tag="KRQ43_003669"
     CDS             1531..2082
                     /locus_tag="KRQ43_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HBH2744000.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT         1018 a          222 c          327 g          833 t
ORIGIN      
        1 gaaacattat aacagaacta aagagaataa attaactaat ttatttttat tataaagtaa
       61 ttataaatgg taaatttaat tgaaagtaga tttaacttat actttataca ccaagtatca
      121 taaattaata ctactttgaa aaattttaaa aaaagtaaaa gttatgataa taaaaataat
      181 attaaagata ataagatata taagaaactt gaaaaaattt gtaattttta gttatatata
      241 tattataatg aactagttaa aaatttttat gagggggaaa atatgaataa gaagaaaaaa
      301 ttgattggga tagctatatc ttttctactt ataatcagta ttataaatcc attacaagta
      361 gaagcagaag ctattattga gtctagtgta tacatttctt caataaaaga gaattataca
      421 tatgataata ctaaatttaa aactattaaa tctaaaagta gacataaaag taggaaatat
      481 aataaaagta aagtaaagtt gaaaaaacga agtataagaa ctaaaaagta tggatatcaa
      541 actataaata aatataaaag acgaaatgca agaagacata atatcctaac aaaattagta
      601 ttgtccataa tagtcatatt tttggttata gttttagtag tgctaatatt tattaaaaga
      661 aagaagaaaa aattttacta aaaataatta aaagaatatc atttttctaa tcattggtat
      721 ctatttaata atatgatgta attaaaatgg agtaatattc tgtttcaaag gaggcatata
      781 aatacaggaa tgagtattaa atgatggtta attaagtaaa tttattgata aatgtactta
      841 attaactttg aagaatttaa ttcctcatga atcaaaatat aaaattacat caacagttat
      901 tcacaaaatt aatataagaa gaattagagc caaagagcag actattagac cattaaagta
      961 attattcata gaattttgta tatgaaaaga aatgtatagt ataatttact ttttttataa
     1021 aaaatagatt acaaaatata ttttttataa aaaggtattg acatttttta gaaaaaagaa
     1081 tatcattatt ttaacaacaa aattcaatac aataaattaa atcctatgac aaggaagagt
     1141 agttaaattt aggttcagta tagagagctg aggatggtgg aatcttagca agaaaaaatt
     1201 tgatgaatgg cccttagagg aataaattga aatcatagtt ttgagagtag actttatcgt
     1261 cagtcgcacg ttatagcgaa taaggtatgt aagtacctga taatgagatg tatgaaaatt
     1321 gaattttata ttaattttta tataatttag gtggcaacgc ggataatctc cgtcctatta
     1381 gtttaggacg gagtttttta ttttactgaa aatttaaaag atagaaggtg gtgagaaaga
     1441 tgttatgaat ttcaaaagct aaagatgatg atatagtagg ttggcaaaaa aataaattga
     1501 aaattaaaaa aataggagga agtacaaaaa atgaaaacaa atacaaaaaa attaacttta
     1561 aatgcaatac ttttagcgat gggattatta atacatcaaa tcacaccagc tataggatta
     1621 ccaatgaagc cagatgtacc actagcaatg ttatttgtaa tattggtttt aaatagagat
     1681 gattataaaa cttgtttgat agcgggtata gtaacaggaa tatttacagc acttacatca
     1741 agttttccgg gaggtcaaat tcctaatgta atagataaaa ctcttacagc aaatatagta
     1801 tttttattaa tgaatattag ttataatatg ccttttataa aaaaattagc taagaaaaca
     1861 caagatactg tagtagttgc aataataatg ccaataggaa ctcttgtaag tggaactatc
     1921 tttttattag cagctcaagc tatagttggt cttccaggag cttcatttac agctttattc
     1981 ttagcagtag tattaccagc tgttttaata aatctagttg caggaatatt tttattcaag
     2041 attgttagtc tatcaataag aagagttagt tatcaagctt aactacgaaa taatatttta
     2101 ctttataaag cattataata actaaataac ataagaataa agtagattat aactatttta
     2161 ttcttatgtt gtttaaagat ttggtattat atatttattt ttaataaaat atttatatag
     2221 taccaattac acttaattta acagataaat tatcatacct atataatatt cttatatgta
     2281 tctcatttgt agttattaaa tataagatat atttaattga cttttcaaga taaattttta
     2341 tattaatctc ctctgatttc tcattttttg aatacactaa aatttccaat taaatcaatt
//
LOCUS       DAEQJM010000162         2299 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.166, whole genome shotgun sequence.
ACCESSION   DAEQJM010000162 DAEQJM010000000
VERSION     DAEQJM010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2299
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.166"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            83..>2299
                     /locus_tag="KRQ43_003670"
     rRNA            83..>2299
                     /locus_tag="KRQ43_003670"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          678 a          459 c          649 g          513 t
ORIGIN      
        1 atctaatttg taatatataa agctgataac tttttaaaat tatcgaagtt gatagcttct
       61 aatctatcaa acctttttaa ctggtcaagt tattaagggt gcagggcgga tgccttggca
      121 ctaggagccg atgaaggacg tgataagctg cgataagctt cggggagttg cacgtaaact
      181 ttgatccgaa gatttccgaa tgaggaaact cacttagagt aatgtctaag tatcattaag
      241 tgaatacata gcttaatgag gggaactcag ggaactgaaa catctaagta cctgaaggaa
      301 gagaaagaaa ttcgattccg taagtagcgg cgagcgaacg cggattagcc caaaccaata
      361 aagttttctt tattggggtt gcggacatat cataacgaag aggtatcgta attgaagagg
      421 tttggaaaga cccaccacag aaggtaatag tcctgtatgt taaacgagaa gacttcagat
      481 atgatccaga gtaccacggg acacgtgaaa ccctgtggga agcaggaggg accaccctcc
      541 aaggctaaat actacctagt gaccgatagc gtatagtacc gtgagggaaa ggtgaaaaga
      601 accccgggag gggagtgaaa tagaacctga aaccctgcac ttacaagctg tggaagcaca
      661 tttcttgtgt gaccgcgtac tttttgtaga acgggccaac gagttacgtt aagtagcaag
      721 gttaagcact taaggtgcgg agccgtagcg aaagcgagtt ttaactgagc gttcagttac
      781 ttgacgtaga cccgaaaccg ggcgacctac ccatgagcag gatgaagcga aagtaaaatt
      841 tcgtggaggt ccgaacccac gagcgttgaa aagctcgggg atgacttgtg ggtagcggtg
      901 aaattccaat cgagcccgga gatagctggt tctccccgaa atagctttag ggctagcctc
      961 aaggtgagag atacggaggt agagcactga atgtcctagg gggtattgca cctaccgaag
     1021 actatcaaac tccgaatgcc gtcatcttat acttgggagt cagactgtgg gtgataagat
     1081 tcatagtcga aagggcaaca gcccagatcg tcagctaagg tccctaaatg taagttaagt
     1141 ggtaaaggat gtgggattgc acagacaacc aggatgttgg cttagaagca gccactcatt
     1201 caaagagtgc gtaatagctc actggtcgag tgatcctgcg ccgaagattt ccggggctaa
     1261 aacttactac cgaagctacg gcatcagtaa tgatgggtag gggagcttcc catacgggtt
     1321 gaagcatgac cgtaaggaca tgtggacagt atgggagtga gaatgttggc atgagtagcg
     1381 agatgtgggt gagaatccca caggccgtaa acccaaggtt tccaggggaa ggttcgtccg
     1441 ccctgggtta gtcgggacct aagctgaggc cgaaaggcgt aggtgatgga caacaggttg
     1501 atattcctgt actaccgata accgtttgag agaagggatg acacagtagg ataagctaag
     1561 cacactgttg gttatgtgtg cccaagcatt gaggcagtca aagtaggcaa atccgctttg
     1621 ataatgctgg gatgtgatgg ggagcgaaat ttagtagcga agtagctgat ttcacactgt
     1681 caagaaaagt ctctatcgag gttaaaggta cccgtaccgc aaaccgacac aggtgggtga
     1741 ggagagtatc ctaaggccag cgagagaact gttgttaagg aactcggcaa aatgaccccg
     1801 taacttaggg ataaggggtg ccaccatcag gtggccgcag agaataggcc caagcgactg
     1861 tttaccaaaa acataggttt ctgctaagtc gcaagacgat gtataggagc tgacgcctgc
     1921 ccggtgctgg aaggttaagg ggatctgtta gagcaatcga agcagtgaac ttaagcccca
     1981 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
     2041 ccgacccgca cgaaaggcgt aacgatttgg gcactgtctc aacaacagac tcggtgaaat
     2101 tgtaattccg gtgaagatgc cggatacctg cgacaggacg gaaagacccc atggagcttt
     2161 actgtagctt gacattgggt cttggtacta catgtacagg ataggtggga ggctttgaaa
     2221 ccaggacgcc agttttggcg gagccatcct tgggatacca cccttgtagt actgggactc
     2281 taaccatagg ccatgaatc
//
LOCUS       DAEQJM010000163         2258 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.167, whole genome shotgun sequence.
ACCESSION   DAEQJM010000163 DAEQJM010000000
VERSION     DAEQJM010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2258
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.167"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(469..1797)
                     /locus_tag="KRQ43_003671"
     CDS             complement(469..1797)
                     /locus_tag="KRQ43_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH2744001.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGDKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGIKR"
BASE COUNT          830 a          378 c          233 g          817 t
ORIGIN      
        1 aaataataaa taccaaaaca actatttgcc acatttttaa tacatacatt atatattcat
       61 attgtctaat ttttgttatc aaataaaatt ttctaatctt atttataaat cacgatattg
      121 atcaggtaat attttctata taatacaata ttctatttta tataacagaa agatttaatt
      181 ttcataaaac ctatgtataa tatttgttat atagatatca cttagtttga aaaaaaaaca
      241 ctttaaaata aagtatctta aagcaaataa ttttttagat gtttaatttt ataattcaaa
      301 aactaaaaat aaagtgaata ccttaaaata aactttttag ttcatagaac actctttttt
      361 tataaaataa aacatctctt taccctttta acaataaaaa agagacttat ctctattttg
      421 agacagtctc ttttatttta attataaagc atttgtaaac tacttggttt atctttttat
      481 tcctctagtc atataagcat acactggtaa gcctatagct gttattacaa gacctcctat
      541 agatatcata gtagttttca tccctgcaaa acacaattga ttaactacaa caaatatacc
      601 acttgctata gctattatag gaacaatagg atataatgga actttatact ctcttggtat
      661 atttggatga gtctttctaa gtttcataac ccctataaaa gttaatacat agaatatcca
      721 agtagcaaat acagctaagt cagttaataa attaaattga cctgacaaag catatataga
      781 tgcaataaca gatactaatg ctattgcatt tgctggaact tgagcagaat ttaatttaga
      841 aaatatacca tactttggta aagtcttatc tgtagctaaa gtatatgcca cccttgaacc
      901 agttagtaaa aatccattta atgctccaaa cactgaaatt aatataccta cagatattat
      961 ttttccaccc attgaaccaa atataacttc agcaactgct gatgcaggag aagcataatt
     1021 tgctaattca ttagctggta atacccaaag atacgctaaa tttattataa aataaacagc
     1081 cataacaact gacaatccac ctattatagc ttttggaagg tcttttccag gattcttcat
     1141 ttctccagct aaagtaccaa cattcatcca tccatcaaaa gcaaataata tagcaattaa
     1201 aacttgacct agtacactac ccaggcttaa tccttcacca accataggtg taagtattgg
     1261 attatttcca ccacctttaa taaatccaac aaccattatt aaaataagtg gtattaactt
     1321 acaaattgta gagacagttt gtatgactcc tccagttttt gaacctaaca tattaagccc
     1381 tgcaactatt actataattc caattgctat tggaagtaaa agtgatgggc taccaattag
     1441 tgctgatgct tgttctccaa atataacacc taatgctgcc atcatccctg gataaaataa
     1501 tacaatttgc atccatccag ttaaaaaacc taatttgtct ccataaattt cttttatata
     1561 taccatcatt ccaccagttt ttggtatcgc aactgatact tctgcagctg taagaccagc
     1621 tgttatagtt atgattccag ctattaacca tgccaatata ccaagacctg gagctcctcc
     1681 agttaatgta tagactgctt gtggtttaaa aaatacgccc gctcctataa cagaaccaac
     1741 aacagttgat aatgctgctg atacgccaag agtctttttc agttcattac ttcccattct
     1801 tttcctcctc attaatccta tttaatttta atttcatagt taaataagca tatattatgc
     1861 caatatatag aaaaatagct tttttattta ttaaaataaa ataaactcta cttagctttc
     1921 gtaatctttt acttttagtt atgtttaaat ataaaaaaat tataaaaacc aaaaatccaa
     1981 atataataat atttataaat aaacgtattt tttatattgt ataatataca ttgtatattt
     2041 gtaacactaa aaatagatta taactattaa gttaaattga ttttgatttt tttgcaataa
     2101 aatttcattt ttttcaaaaa cattttggct tctttctgta attttctatc tttaaggtct
     2161 tttatataat agtatgattt ttgcttgttt tatagtctat tttatattaa taaataattt
     2221 gacaatttat tataacccaa tttaaaccat aaatcaaa
//
LOCUS       DAEQJM010000164         2070 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.168, whole genome shotgun sequence.
ACCESSION   DAEQJM010000164 DAEQJM010000000
VERSION     DAEQJM010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2070
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.168"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(333..2018)
                     /locus_tag="KRQ43_003672"
     CDS             complement(333..2018)
                     /locus_tag="KRQ43_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2744002.1"
                     /translation="MKYLIEIAKKERLLVFIYLALGIGIELLNSFSANYYQSLIDRFN
                     NSTINFHIIFIYGTVLVTLCLLRYIDEYPGRRLEHSFFLDLKLKALEKMSKIDYLEYQ
                     MLGTGKLIQKIENGANAGRNIFFNFLLAVVRKIIPSILFSMVFIYRIDKKVMFTILIG
                     YFIVFIITNLLIKALYQIKEHILINEEKMNHFLVRGFVEMVVFRVNKRFEYEICQSKF
                     AKKEIIDSRVKMTLIHEAFFTIFSLIVTFIKMLIIVYSWKTKTISIGSIIALITLLDN
                     AYTPIAIFNVLYIQFKLDKAAYKRYTDILELNNDGQLLAGKEVNLMYGNIEFNEISFL
                     YNNKREIFNKLSLSIKSGEKVAIVGESGSGKSTLIKLLIGLLKPSEGTIFIDDYNLLE
                     MNLNSYYNYVTYVSQDSPIFDGTLRENIVFGKTIKSNDIIEVLEKVGLKNLYLKLEAG
                     LDTKLGEKGTTLSGGEKQRLALARLWFSDAKIIILDEATSALDNITEEKVMLNVMEFL
                     KDKTTIMIAHRFNSIKNVENIIVLKEGSIIGSGSFKKLLDGNLYFRELYYTMS"
BASE COUNT          767 a          312 c          163 g          828 t
ORIGIN      
        1 tatattttta tattttaata atttagttta actatttttc tatgctattt atatagaata
       61 tttctaataa ctcataaatt ctaatctttt aatatctatc cctcaattaa tggatatgaa
      121 tttatttaat ttaaatactt gatatttttc atatttatat aaaaatatta cattttaaat
      181 acaagttaat aaaaatggaa gaatatatgt taatgtaaat attaagaata atactaaaaa
      241 atattactgg aatctcaaat ttttaataat attccagtaa tatttaaata atattaaatt
      301 aagaaaaata ttttcttata cttacataat aattatgaca ttgtatagta taattctcta
      361 aaatataaat taccatctaa tagtttttta aagctaccac tacctattat actcccctct
      421 ttaagaacaa ttatattttc aacattctta attgagttaa atctgtgagc aatcataata
      481 gttgttttat ctttcaaaaa ttccataaca tttagcataa ctttttcctc tgtaatattg
      541 tctaaagctg atgtagcttc atctaatata attatcttag catctgaaaa ccaaagcctt
      601 gctaatgcta gcctctgctt ttctccacct gataatgtag ttcctttttc acctaattta
      661 gtatctaaac cagcttctaa ttttaagtat aaatttttta aacctacttt ttctaagact
      721 tcaataatat cattactttt tatagttttt ccaaatacaa tattctcacg taaagttcca
      781 tcaaatatag gtgaatcctg tgacacatat gtaacataat tatagtaact atttagattc
      841 atctcaagta gattataatc atctataaat atagttcctt cgctgggctt taataatcca
      901 attaatagtt taattaaagt tgatttacca gaaccactct ctccaacaat agctactttt
      961 tctccacttt taatacttaa actaagttta ttaaatatct ctcgcttatt attatacaag
     1021 aagctaatct cattaaattc aatatttcca tacattaaat taacttcttt acctgctaac
     1081 agttgaccat cattattaag ttccaaaata tctgtatagc gtttatatgc tgctttatct
     1141 agtttaaatt gaatatacaa tacattaaaa atagctatag gagtatatgc attatctagt
     1201 aaagttatca atgcaattat agaacctata cttattgttt tagttttcca actataaact
     1261 attattaaca tttttatgaa cgtcactatt aatgaaaaaa tcgtgaagaa agcttcatga
     1321 atcagtgtca ttttaaccct agaatcaata atttcttttt tcgcaaattt tgactgacaa
     1381 atttcatact caaatctttt gtttacccga aatacaacca tttctacaaa tccacgaact
     1441 aaaaaatgat tcatcttctc ttcattaatt aatatatgct ctttgatttg atatagagct
     1501 tttattagta aattagtaat aataaaaact ataaaatatc caattaatat ggtaaacata
     1561 acttttttat caattctata aataaaaacc atactaaata aaattgatgg aattattttt
     1621 ctaacaacgg ctaataaaaa attaaaaaat atatttctgc cagcattagc tccattttca
     1681 attttttgaa ttaattttcc agtgcctaac atctgatatt ctaagtaatc tattttactc
     1741 attttttcta aagcctttaa tttcaaatct aaaaaaaaac tatgttctag tcttctacct
     1801 ggatattcat caatatatct taaaagacat aaagtaacta atacagttcc atagataaaa
     1861 attatgtgaa aatttatagt actgttatta aatctatcta ttaggctctg ataataatta
     1921 gcactaaaac tatttaaaag ttctattcct atacctagtg ctaaatatat aaaaactaat
     1981 aacctctctt tttttgctat ttctattaaa tatttcataa ctgtacacct atccttattt
     2041 attttacttt attaacttaa aataatttta
//
LOCUS       DAEQJM010000165         2047 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.169, whole genome shotgun sequence.
ACCESSION   DAEQJM010000165 DAEQJM010000000
VERSION     DAEQJM010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2047
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.169"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(165..383)
                     /locus_tag="KRQ43_003673"
     CDS             complement(165..383)
                     /locus_tag="KRQ43_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH2744003.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            complement(384..791)
                     /locus_tag="KRQ43_003674"
     CDS             complement(384..791)
                     /locus_tag="KRQ43_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2744004.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            complement(877..1365)
                     /locus_tag="KRQ43_003675"
     CDS             complement(877..1365)
                     /locus_tag="KRQ43_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HBH2744005.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            complement(1545..>2047)
                     /locus_tag="KRQ43_003676"
     CDS             complement(1545..>2047)
                     /locus_tag="KRQ43_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2744006.1"
                     /translation="GIHILNHVKYNHIEDYVNCLRLTMDGHPNIYSSKTALYFIELPK
                     IRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIKRALDRLKELGSNEDYLLNLKR
                     GAYIMNKSRNFKEEIFQEGVEKGKREEKFNIIIKLKNKGYNLSEICDIIDDLNKSEVE
                     KIYNQN"
BASE COUNT          696 a          336 c          181 g          834 t
ORIGIN      
        1 atcattcatt ctttaatcta tgagcttggt ttttcatcta taagtcattt attctctaat
       61 ctataagctt ggttttttac ctataattaa ttcattctct aatacataaa cttgaatttt
      121 ttatctatta attcattctc taatgcataa gtaatacatg aaatttaaat attattttct
      181 tcaataaatt caaacaactc ttctacagtt gtatcaaata ccttagcaat atccattgcc
      241 agttttaaag aaggattgta gcgaccattt tctaaatgta caatagtttc acgtcttact
      301 cctactgact ttgcaagttc accttgtgtc ataagattct tttctctata ggatttaatt
      361 tttgtcttta gtaatactga cacctaattg tatatcccct ttctgtcaaa atatataaat
      421 agaattaact tcaacaagga ttgaataaac aaaatgacta ataaagacat tcctatattt
      481 aaatttgaca catttatgtc caaagttaca agaaatatag atactatagc tacagaaaaa
      541 aacaatactt ttattgcaat atcattaact cttgatagta tacattttga tgcctcatca
      601 attaaatcat catacttttt attatagacc cactgagctc ccatagctaa tacccaaata
      661 attataggaa gatattcaat actacttcct ttaaaaaaat acttatttac taatgtagct
      721 ccaatacaat aagaaattcc caatatttct gaaataagtg ttgatttaat accagtttgt
      781 tgtttagaca tataaaatcc cccttaaaaa gttatgtatt tataacacct cttgttataa
      841 atatataact tttttgaata aatttcaata aaaatattat tttgcaacaa attcttttat
      901 taattttaca ttagatagag gcactttaga tgtcactcct tgcaatgtca aatcttctat
      961 attaacttca tttaattttg aacacagttc taagtcaaat attctttccc aacttacctt
     1021 cttttcaatt tgttcatctt cataaagctc tacagtaata tccattaaag gtaaatgcca
     1081 taaatcaaat tctgataata acacattgtc ttcacttatt tctatttcaa gtaaaacacc
     1141 tttttttcct ttttctaaat aaccactaca tcttaaatca ggtctcttcg tccaaaccca
     1201 tatcatacta tcatcaaatt catatattct atttgtcatt tgactataca tccatttgta
     1261 tggaatatca aagtcttcta atataaaaga ataatcattt gatagatatt tattgttttt
     1321 attgttgttc caaaattcta aagtctgtat agtataaaat ttcatatata aatcaacccc
     1381 tttgtttttc tataagaagg agatagttca aacttttatt ttgaatcatc tccttagctt
     1441 atatatctct ttgtatctac tatagttaaa taacaaggtt ttatattaat ttaaatttaa
     1501 aagaggaagc tttatattta tctagtgcca tctcaattat agtattagtt ttgattatag
     1561 attttttcaa cctctgattt attcaaatca tctataatat cacatatttc actcaaatta
     1621 tatcctttat tttttaattt tatgatgata ttaaatttct cttctctttt ccctttttca
     1681 acaccttctt gaaaaatttc ttctttaaaa tttctacttt tattcataat atacgcacct
     1741 ctctttaaat ttaataaata gtcctcatta ctgcctaatt cttttaatct atcaagtgct
     1801 cttttaataa cataatctgt tttagatagt attctaatat caatatgaga aggattatca
     1861 ataagtttac cccatattag aactctgttt gctatacaac tggatttacg aatttttgga
     1921 agttctataa aatataatgc agttttacta gaataaatat ttggatgccc gtccattgtt
     1981 aatctcaggc aatttacata atcttctatg tgattatatt ttacatgatt tagtatatgt
     2041 attccaa
//
LOCUS       DAEQJM010000166         2024 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.170, whole genome shotgun sequence.
ACCESSION   DAEQJM010000166 DAEQJM010000000
VERSION     DAEQJM010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2024
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.170"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            394..624
                     /locus_tag="KRQ43_003677"
     CDS             394..624
                     /locus_tag="KRQ43_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2744007.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            617..1198
                     /locus_tag="KRQ43_003678"
     CDS             617..1198
                     /locus_tag="KRQ43_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH2744008.1"
                     /translation="MNNKKHWYDYLWIFSSIYLVLGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
BASE COUNT          738 a          169 c          366 g          751 t
ORIGIN      
        1 gcttaacttg tgattaatag agtaagagtg taactaaaga taaacttcaa tatgagttta
       61 acttgtggct aatagaataa gattgtgaat aaagttatag ttttagatgg gtattaacct
      121 gttactaata gaatatgatt aggtgtaaaa ttatagagct gtataagaaa atattataga
      181 tatattaaat attagataat aaatatttat atagatacac aaaagaaaag gcgatatgaa
      241 gctaaactta atgacttcat atcgtttttt atttgaaact cctttgtatt tagagtgtga
      301 tttttaatat tgaggtttta tgtgattaag tcacagataa aaagtaagta tcttgatata
      361 attcttatag attaataata tagggaggtt attatgtcta ataaaaaaaa gaagtatgca
      421 aatattttag caaatgagtg cgttgcttgt ggtagctgta taaaagcatg tccaagaagt
      481 gctatctcag ttccatgtgg cattagtgca aaaattaata gagatttatg tgttggatgt
      541 gggatttgtg aaaagatatg tccagcatct gtaattgaga ttataacaat attaaaagag
      601 gaagaaggta agtgtcatga ataataaaaa acattggtat gactatttat ggattttttc
      661 ttcaatatat ttggtattgg gatttgtaaa tattattttc gcttggattg ggctaatttg
      721 tttctttgtt ccactagcta tttctattgt taagggaaat aaagcttact gtaataagta
      781 ttgtggaaga gggcaactgt ttaatttgct tggaaataaa ttgaagctgt caagaaatag
      841 agatattcct aaatttatta gaagtaagtg gtttagatat gggtttttga cattttttat
      901 ggtaatgttt gccaatatgc ttttttcaac ttatttagtg tttgaaggaa gtagaaattt
      961 taaagaagta gtgactttgt tgtggactat aaaaatgcct tggcaatggg cgtatcatgg
     1021 aactttagtt tcaccttggg tggtacagtt tgcatttggt ttttatagtg ttatgcttac
     1081 atcaactgtt cttggtttga ttactatgat attgtttaaa cctcgttcat ggtgtgttta
     1141 ttgccctatg ggtactatga ctcagatgat atgtaaggca aagagtaagt ctgtatagga
     1201 agagattttg tgaagattta aggggtttaa tgtttaaagc tagagttgat ttaagaaaat
     1261 aagaaagata taaatatcta aatatgaaat agattcaaga tgagtaatag tttctattag
     1321 ctatgatagg tatatgagtg gagcataaat gaagtttgta taaagtaaac tcatttatgc
     1381 ttctttttta catgatacat tactaattaa atagaaaaac aatgtaacaa cttgtatttt
     1441 aagtacgtca gagaaatctg aagaaatgat aaatgttata gaagattgta aacttatgct
     1501 taaaacaagt aatagatatt taaaggaagc agattaaatt tcaagaagtc ttacgtgctt
     1561 gttgaaacat aaactggatt tgttacagat aaactaattt atacaatatt ttttaattaa
     1621 tatgttttca ttactatata ttatatgtta atacataaaa aaatggtggc tgttttatta
     1681 aaggtaggtc aatgacattt cttataaaaa taaattctaa ctttaaatta acttaggagt
     1741 tctgtataat aattatatgt tgaaaatatt atgaagtttt gcttatacaa taaataattg
     1801 attttatttc tggtaaaggt gatagaaaaa taaatattca gattatatag taaatttaac
     1861 tatatatatt aaactataaa aaggagattt tatatgatga aacgagatat ttactcagta
     1921 cagttagatt atatgttagc ataatgtact gagtaaaata ataatttgct aacaaataga
     1981 actgtactgc taaaaacttt aggttttgtt aacttgaaat gatt
//
LOCUS       DAEQJM010000167         1999 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.171, whole genome shotgun sequence.
ACCESSION   DAEQJM010000167 DAEQJM010000000
VERSION     DAEQJM010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1999
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.171"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            263..556
                     /locus_tag="KRQ43_003679"
     CDS             263..556
                     /locus_tag="KRQ43_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH2744009.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            537..1178
                     /locus_tag="KRQ43_003680"
     CDS             537..1178
                     /locus_tag="KRQ43_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBH2744010.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVILQI
                     LMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKQNYSVGIILPWTLDDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            1422..1754
                     /locus_tag="KRQ43_003681"
     CDS             1422..1754
                     /locus_tag="KRQ43_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBH2744011.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
BASE COUNT          772 a          175 c          306 g          746 t
ORIGIN      
        1 tatatgtaat atatataagt atatcagtca ttaggttttt gctttaacaa ttgtggtgca
       61 atacactttt gttaaattaa aaaaattaga taaaataaga ttatataaaa gcgacttaag
      121 taaattgaga atcttaatat gaaaattttc aataaatatt tggaaataac tatttagaaa
      181 tttttctaaa tagttattga aataaaatgg atgttatgtt atattctatt tagatgaaat
      241 tctaaatagc gaggtgatgg tgttggggtt tccagaaaca ttcaaagctc tttcagaccc
      301 tataagaaga gaaatattgg ttatgttgag ggagaataaa atgtcagcag gagaaattag
      361 tgaaaaattt aatatgacga atgctacaat ttcttatcat ctatctcaac taaaaaaggc
      421 aggactcata tttgaaacaa agtataagaa ctttattttc tacgaaataa atatttcagt
      481 tttcgaagag gttatgcttt ggttttcaca atttatggag aagggagaaa aagataatga
      541 aaaaagcgat aaataaacaa tttattttat ctactttaat atgttttata ccatttattg
      601 tatcaatata tttttataat agattaccaa atgaagttgc aattcatttt gataattatg
      661 gaaatccaga taattatgct ccaaaggtta tagcagcttt tggtgtacca ttgttaatgc
      721 tatgtatcca tttgtataca tggtttagac ttgagaatga gcctaaaaaa gctaattttt
      781 caaatgttat acaaaattta tcaaaatggg gagttgctat actttcagta attctacaaa
      841 tactgatggt tttatattca acaggagtta gtttggagtc taatttttat acaggattaa
      901 ttttaggaat aatagttatt ttatttggaa actatcttcc taaatgtaaa caaaattact
      961 cagtaggaat aattttgcca tggactcttg atgatgaaga taattggaat aagacacacc
     1021 atttagctgg atggatttgg cttattggtg gaatattatt aattattaat gcatttatta
     1081 atattccttt ttataatatc tttgtaatct ttgtaattgt aatactacca tttatatatt
     1141 cttatttgat gtataaaatt tcaggtaaaa ataactaata taattaatca ctataataat
     1201 gtttggataa gaataatata tttcagaact gagatagata ataaagaaat tactaagatt
     1261 tctattttag ttctgaaaaa atcttactta tatgataact tattgagatt tcaaaaaata
     1321 atataaatta ggctaatgaa cataaaatga aaatttgtat ttaatattga aaatataagt
     1381 acagtgtgat actcttataa gaaaaacata ggaggtagaa gatgaatact agagaaatga
     1441 aagaatatag gggattttac aataaaaaat taagtgaaac agatgagttt tttagagtat
     1501 ttggaagtct tgatgataag acttattcag aaggggctat aagtaaaaaa aataaggaat
     1561 taatgggact agctatttca attttaagcc gatgtgatga gtgtatttgt tatcatattg
     1621 agggttgtat taattctgga gcaagtaaag atgaaattat agaagctata aaaataggtg
     1681 taattggtgg cgggtctatt acatatccaa acgcaagatt tgcaataaaa attttagaag
     1741 aatttaatat ataattttga tacacgtagt ttatttagac taataataat attctattta
     1801 agtctttgaa attaagcttt attttctaag ttcacttctt attaagtttt tagaattgca
     1861 tatataaata taaattttta aataatatag tagttttaaa ttatttacat catagattgt
     1921 attgagaata gtatattgtc attattaaat cttttataca ttttttattt taaataaatt
     1981 gaatattaag gtgattata
//
LOCUS       DAEQJM010000168         1636 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.172, whole genome shotgun sequence.
ACCESSION   DAEQJM010000168 DAEQJM010000000
VERSION     DAEQJM010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1636
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.172"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            238..939
                     /locus_tag="KRQ43_003682"
     CDS             238..939
                     /locus_tag="KRQ43_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH2744012.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKSALKEASNLGIE
                     RKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLLVVFILGHRMRGIVEKMNVKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAVISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIVLS"
     gene            965..1621
                     /locus_tag="KRQ43_003683"
     CDS             965..1621
                     /locus_tag="KRQ43_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2744013.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGLRFGQMPMLSVIFQI
                     WGLVATTYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFITDSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDSNKTKE
                     "
BASE COUNT          529 a          215 c          322 g          570 t
ORIGIN      
        1 accttataag ttaattacag gttaaaaaaa taatatgtga attttctgat atttactaat
       61 tatcaataaa gtatttaagt attaatgttt ttagtgagac tttaagacag ataatctcct
      121 attaaagata ctatatctta gataaaataa attaaaacaa tataaaaaca taacaagatt
      181 acagaaagaa agctcataat aaaacactaa aaaatttatt ttaaggagga ataaagtatg
      241 aagtttcaag aaatgattaa tagcccaggt ctttggattg tttctagttt tttagtaatt
      301 atttcagttg ttcaagcaat cgtatttatg aaatcagcac ttaaagaggc ttcaaatctt
      361 ggtattgaaa gaaaaggaat taaagcagca attcgctcag ctagtgttac agcaattgga
      421 ccctctctat ctcctgttat tacattatta tcactggtag ctgtgattgg tgctcctacg
      481 acttggatga ggctttgtga tgtaggagct gccagaacag aacttggagt aatatctctt
      541 acatcaaatt tatctggagt agaagtaggt agtgctgcat ttggagcaga agctttttcg
      601 tatgcactat ggggaatggc tttaaataac ttaggttggt tgcttgttgt atttattttg
      661 ggtcatagaa tgcgtggaat tgttgaaaaa atgaatgtga aatataatcc tacttgggtt
      721 aaaaaactac ttgcaggggc tacagttgga ttatttgctt accttctttc aaatcaaata
      781 aaaacattcg aaataccaaa acttacacca gcagttattt cagctatagt tatgctagta
      841 ttgacgactt tatttaaaaa gaatcaacga ttacaagaat tatccttagg tattgccatg
      901 ttgattggta tgtttggcac acagattgta ctatcatgat taaaacagat aagaggtgat
      961 aattatgtat gataaaaaga tgataaaaat agggagaatt tctataggtc ttgcaattat
     1021 tgcaaatttt attcctgcaa tctatgtagg tcttcgcttt ggtcagatgc caatgctttc
     1081 tgttatattc caaatttggg gattagttgc tacaacttat ggagtgagtt ggattgttca
     1141 acctatagct tattatccaa cactaggagc tccaggttct tatataggtt ggcttgcagg
     1201 ttctgttgga gatatacgta tgcctgcagc atcaatggca cagaaaattg caggtgtaga
     1261 agcaggaact catgagggtg aagttgtagg aacaattggt acatgttgtt caatctttgt
     1321 atcagcttct atgattacta tttttaccat tgtaggctat aaagtaattc ctttgttacc
     1381 tgaatttatt actgattcat ttaattatat acttccagca ttgtttgggg caatttacgt
     1441 tgatattgcg cgtaaagata ttcgagctgg tggatgtacg attgctgtag cattagctat
     1501 tatgtacttt ggtgaaaaaa ttggtatacc aggtggattg ttgacattgt ttattgtgtt
     1561 aggtgggata cttattacaa gggttttctt tgtaattgat agcaataaaa cgaaagaata
     1621 ggattgttta ctagga
//
LOCUS       DAEQJM010000169         1573 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.173, whole genome shotgun sequence.
ACCESSION   DAEQJM010000169 DAEQJM010000000
VERSION     DAEQJM010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1573
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.173"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            240..1067
                     /locus_tag="KRQ43_003684"
     CDS             240..1067
                     /locus_tag="KRQ43_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH2744014.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
BASE COUNT          596 a          169 c          226 g          582 t
ORIGIN      
        1 ataattttaa catgcccata aaatataata cccacaaatg ataaataata ctcaaaatat
       61 ctattgaaat aactatacat ccttaaataa cttaacttaa atctaaacat ttcaaaaact
      121 tcttaaaaat atgtaaaaat ttgatgataa agtagcgatt ttttcaaaaa aaatgtaata
      181 tagagttata tcttataata ttttagagat aaattttatc atagttggga gaaatttgta
      241 tggatttaag caaaaaagta aaaattttag aaaatgcatc agatggcaaa agcgaatttg
      301 aaatattaga atttgaaaaa cttgagggag cttctagccc attaatggca atgggattat
      361 attttgctag agaagctggt ttgaaagcta gacaaattaa gataaaatta aataattcat
      421 caataaaaac agaagctggt gcattatact attataaagg aaatatatct tctgaaacta
      481 agattggtgg tgttggaggt ctttttaaaa aaggaatatc aggagcactt actaatgaat
      541 caatgatgaa acctgtatac aaaggtactg gagaagttta tttggaacct tcttttagac
      601 attatttatt tatgagtctt gataatgatt ctataattgt tgataaagga ttattctatt
      661 gttgctctga tacaatagaa gtaaaagcat ttacacaaaa gaacttctca tctgctttac
      721 ttggtggtga aggcttcttc caaatagaat taagtggtac tggtgtaatc gttctggaat
      781 gtgttgtacc tcaaagtgaa attgtagagt atgaattgaa aaatggagaa gaattaaagg
      841 tagatggtaa ctttgcaata gcaagaacat ctggggttaa tttttctgtt acaaaatcag
      901 ataaatcttt aattggttct gctttaaatg gtgaaggttt cttaaataca tttactggta
      961 atggtacagt ttggctagct ccaactcaag taatgtatga aaaactaagt tttggagcaa
     1021 tgcctactaa tgataatatg aataataaag tttctaagca aaaatagttg ttttataaat
     1081 atttattaaa tcattattga ttttataaag tcactataaa ttttattaga ttattattat
     1141 aaaatcagag tgtggaaatg tttatgtgta ttctttaaat aaaaatttcc acattctgta
     1201 aggttattat acttgatata taaaattcaa tttaggaaca tagtctaaca tttataaaca
     1261 tattaaggta atgatttctc ttggtaatta ttctcatatc ttattctttg attatattta
     1321 tcttattcct agcccttatg tcatattata tttcttatct tattatttat aattagcatt
     1381 aacttatcta aaatcttgta tttttttaat agtaaagttt acatctatat taaaaagttt
     1441 acatctatat taatttcata aaacaatcaa ggtagtcaag agattcaact ttatttgatt
     1501 ttaaaaattt aagtgaattt gttcttatac acatcttttt aaaattatat ctgtagaaaa
     1561 tatcatttag agc
//
LOCUS       DAEQJM010000170         1505 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.174, whole genome shotgun sequence.
ACCESSION   DAEQJM010000170 DAEQJM010000000
VERSION     DAEQJM010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1505
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.174"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(368..859)
                     /locus_tag="KRQ43_003685"
     CDS             complement(368..859)
                     /locus_tag="KRQ43_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBH2744015.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDENIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASDDGLAVIF
                     FIM"
BASE COUNT          575 a          193 c          130 g          607 t
ORIGIN      
        1 tttctgaaat tttttaagtt tatgaagcta taatttaata tatatttatt ttatttgtga
       61 gtctattttt atatataatg aaaaatgtga taagtatcca aaagaattac tggatataat
      121 aagatagggt atttagcctt ttaagataaa taaaaatatc tgcaactata tattgcaaaa
      181 atttaaaact aatttatata tgctaatata aatatttata aagacataag acaaatttac
      241 ctacagattt aaatttaact tatatatttt aaaaggctaa tataatatgt attttcttct
      301 atacaatcaa aaggcttcat atctaagata tgttatgaca ctaatattca caatttttta
      361 gtaattatca cattataaaa aatattacag ctagtccatc atcagatgct tcttgtataa
      421 actttttaag ctcaattaga tttgcccata catattcaaa aaaatcatct tcactctcat
      481 cattcataac aggataaata ttattttcta acatctcatt aatattaaat ctttttctaa
      541 atgcttgttc ttccaaactg ttcattgctt ttgatagttt ttttacatca tttgctgtaa
      601 tcaacatgac aggaaattct ccatcaattt ccataagtat gtttccactt agtactaatt
      661 tgctaaatat attctcatca tctccaccaa aaggacaacc tgtcaaagta aagtgaatgg
      721 catgccatgc tttatcaata ttgatagtac tattttcgtt ggcatcttca aaaacaaaat
      781 cttgtaaatt ttcttctgct tgctgtaatt taaaaacatt ctcttcactt attttagtat
      841 aacatcctat catccccata attacattcc tcctaagtag cgttttttta attgtaactt
      901 ataattaaac ttagttacaa taaaatatat tgagaaaagt attatttcat cttaaattta
      961 aatacctata ttatcaacta aaattctgtg tttatagcgt aagtattatt attttttcct
     1021 aaaaattaaa tgaatcagaa gttctatagg caatattgac tataaataag aactattact
     1081 tttaaaaaaa atttaagaaa ttatactgta gaatcatgct ctacttatta gcttcaaata
     1141 aaaaataaat catgttctca aattaaataa taaataacaa taaatttaaa ttttaaacta
     1201 taagagtttc tgaagtgtta ataagcatac caataattat atgtgtaaga atttgattta
     1261 atagatatga ataattttta cattaattat aaatatatta acctattatt ataaattcta
     1321 taaaaagaaa agttatctta aataaaaaat aagtgtatct taaattttaa atgatacact
     1381 tatttttata ttgaaattat attttttaat atctattctt aattaggtat ttttaaatta
     1441 tctgtttaca ttaaatatct cttaattact tatctttcag ctagcttctt ctattaaatg
     1501 tttct
//
LOCUS       DAEQJM010000171         1426 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.175, whole genome shotgun sequence.
ACCESSION   DAEQJM010000171 DAEQJM010000000
VERSION     DAEQJM010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1426
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.175"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..843)
                     /locus_tag="KRQ43_003686"
     CDS             complement(<1..843)
                     /locus_tag="KRQ43_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HBH2744016.1"
                     /translation="MNNYMLYVFDNLIKTTIVCSFGICLLLFLKRYFFKRFSKRFNYY
                     IWLVIVFRMLLFLFNYTVMYEVKEPKENTVGNNITQIDVSIDNDFMLYLVYLWLFVTI
                     AIAVYTFMEYTKFKNLVVDVSYDIEDHDVNCIYKNLLKELDIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYTYSKDELTWILKHELMHFKNKDILIKFLVLSVKIMYWFNPLVYI
                     MSNKVNLDCELCCDESVLTDCSLKDKKAYALALIKSIKLSKNYNSGILTTEFNKTSLE
                     KRLDS"
     gene            complement(836..1213)
                     /locus_tag="KRQ43_003687"
     CDS             complement(836..1213)
                     /locus_tag="KRQ43_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH2744017.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDATVTSKDVIEVMEQKYGWKQTTT
                     LTLLSRLVKRGFLNAQKIDRYTHYTVIVKHKDYLSFETKDFLSNIHDDSLKSLISALH
                     DDENIGKDTLDFLESYFDNLKNE"
BASE COUNT          506 a          223 c          129 g          568 t
ORIGIN      
        1 actgtcaagt ctcttttcca gacttgtctt attaaactct gttgttaaaa taccactatt
       61 ataattctta ctaagtttaa ttgactttat aagtgctaac gcatatgctt tcttatcttt
      121 taaagagcaa tcagtcaaaa cactttcatc acaacataat tcacaatcta gatttacttt
      181 attgctcatt atataaacaa gtggattaaa ccaatacatt attttaacag acaaaactaa
      241 aaactttatt aaaatatctt tgtttttaaa atgcattaat tcatgtttca aaatccaagt
      301 taactcatct ttactataag tatagtctgg taagaatatg taagatttaa ataatcccat
      361 acctgctgga cttatcaatt catcagaacc tcttaactca attttctttt ttatgtctaa
      421 ttcttttaac aaatttttat agatacaatt tacatcatga tcttcaatat cataagatac
      481 atcaacaacg agatttttaa attttgtgta ttccataaat gtataaactg caatggctat
      541 agttacaaat aaccataaat aaactaaata cagcataaaa tcattatcta tagaaacatc
      601 aatttgtgta atattatttc ctactgtatt ttccttgggc tcttttactt catacattac
      661 tgtataatta aatagaaaaa gtaacattct aaagactatt accaaccaaa tataataatt
      721 aaatctctta ctaaacctct taaaaaaata tcttttcaaa aataataata gacaaatacc
      781 aaaactacat acaatagttg tctttataag attgtcaaaa acatatagca tataattatt
      841 cattctttaa attatcaaaa taactttcta aaaaatctag cgtgtcttta cctatatttt
      901 catcatcatg taatgctgaa attaagcttt tcaaagaatc atcatgtata ttacttagga
      961 aatcctttgt ctcaaaactt aaataatctt tgtgttttac tattactgtg taatgtgtat
     1021 atctgtctat tttttgagca tttaagaatc ctctttttac taacctcgat aaaagtgtta
     1081 gtgtagtggt ttgtttccaa ccatattttt gttccataac ttcaataaca tcttttgatg
     1141 tcactgtagc atctactttc caaataaatt tcattacttt tagttctgct tgtggtattt
     1201 ttcttatcat catttacacc tccctcaaaa ctcttgctac tttaagtcta caatatgtga
     1261 attttttagt caaacgcttt atgaaaaaat gtggattttt gtacttttta ttaattttct
     1321 aattttttaa aatactaaaa gttagatttt aaaatatagt tgttcaagta ttttgctttt
     1381 tacatattta attataatag tgcagaatgt tatttccaca ttaaaa
//
LOCUS       DAEQJM010000172         1418 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.176, whole genome shotgun sequence.
ACCESSION   DAEQJM010000172 DAEQJM010000000
VERSION     DAEQJM010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1418
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.176"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            428..895
                     /locus_tag="KRQ43_003688"
     CDS             428..895
                     /locus_tag="KRQ43_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH2744018.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDILGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKGIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEIGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          575 a           94 c          202 g          547 t
ORIGIN      
        1 attagaaaga ttatgaaaac taaattagaa gaactaaaaa ctatattttt attaattata
       61 atatttgaat aatcttttta atcatataaa atgcatatac ttgtaatatt taaaggtgat
      121 attaatatta ttagtgtata ttaatattcc cttgaaatta aaaaaacata gatatttcag
      181 taatctaaaa tagtctacaa aaataacagt tttagcaaaa ttaataagaa tacatataga
      241 tttaaaccta aaagtatgaa catgtctgtt ttttacaaga ttaaaattta tattatatga
      301 taaaattaac ttaactattt caataagact tataattttt ttctttatac tagaccttat
      361 tgaaaccttt atagtttaat tctaattata tattataaat aaagtatgtg tatattaagg
      421 aggtaatatg aagtttttaa atgttttaat agtagttgaa gatattgaga aatcaaaaaa
      481 gttttattat gatattttgg ggttaaaggt aatctgtgat tttggagaaa atgttgtatt
      541 agaaggtaat atatcattac aagaaaaaaa gctttggtta gaatttatta ataagagtga
      601 cagtgaagtt aagttcaatg gaaatgatgc tgagttatat tttgaggaag ataattttga
      661 tacttttgtt gaaagattga gtacaatgaa aggtatagat tatgttcatc tagctataga
      721 gcataggtgg ggtcaaagag caattagatt ttatgattta gatgggcata ttattgagat
      781 tggagaaact atgtcatctg tgtgtagacg ttttttagat agtggtcttt caatagatga
      841 ggtagctaaa agaatggatg taactgtcga atatattgaa tcagttttag aatagatgga
      901 ttatattaaa gtaaaactat attttgtata gaagtaaggg ctgtaagtaa acttgtatgg
      961 aaacaaattt acttacagtt tttgtttttg taagatacag aatataatat ttgttataat
     1021 tttatttgga tttttaaaaa gtgcatgatt ttccttacat attataatag aatttaatat
     1081 ttattggatg atttaaattt agaaaaatat aagtattagc ttataaaaga taattatact
     1141 tactatcaag ctgtagaatc atatatacta ttttatgtaa ttatgttaaa atttaattga
     1201 acaaattaaa aatatagtga aaattgtagt tttagtttat ttatttaata aatatttcaa
     1261 ataaaataat gtttaaataa gaaacataaa taataatatt attattgttc ttaaagacaa
     1321 aaaatcttag cttaaaaatt tgtatcatat aaaatcccta catattatgg aagtaatgat
     1381 acattatatg atatacacaa taaagtataa aagtattt
//
LOCUS       DAEQJM010000173         1246 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.177, whole genome shotgun sequence.
ACCESSION   DAEQJM010000173 DAEQJM010000000
VERSION     DAEQJM010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.177"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            256..1218
                     /locus_tag="KRQ43_003689"
     CDS             256..1218
                     /locus_tag="KRQ43_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH2744019.1"
                     /translation="MNLQSKWVNFLKPTYVSDEIKRKKLQVIIFFSITYGLSYSLGLL
                     AICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFYSSVILFFIIYFFIFI
                     IESLKLISINQFQLMYFMLILISSLCVIIYSYKITSLYIFKNFKIGILLVFYFLFSQI
                     IFGLIISDNQFDYKNFLNYILLPIISLVYIYPFLCEEYGWRSFLQSILFDRFGKKIGI
                     VMVGTCWSLWHLPLQFTLYSPQTPIIGAIAHLIYGIGLSIFLGYVYMKTKNIWFCSIM
                     HVLINSLGLIFNDSEIIINYHSIIQRLIFILLFYTPFLFTKEYK"
BASE COUNT          465 a          106 c          147 g          528 t
ORIGIN      
        1 tattaaaaaa ataatagtaa actgattgca taaaaatgat ttttatataa attttaaaca
       61 gaagaataaa tttctaacga aattggatat ttcttctgta aatacatatt caaaaaaaga
      121 attataagag tttagtcagc agtcgtgtaa gtaataagga ctttataaat atatagaaat
      181 ataatgatat gagtataagt agaaaaattt tatgattttt acaattattt tttataaaaa
      241 gggaggttat gtttgttgaa tttacaatca aaatgggtaa actttttaaa gccaacatat
      301 gtcagtgatg aaataaaaag aaaaaaacta caagttataa tatttttttc tataacttat
      361 ggtttatctt attcactagg tttattagca atatgtttta atcatttaat agattcagaa
      421 attttagctc aatttatgat gatattgcca ttatcttcag tttctattgc aaaattttac
      481 acagaaggaa gaaataatga taaatataat ttctattcat cagtaatatt attttttatt
      541 atttactttt ttatatttat tattgaatca ttaaagttaa taagtattaa tcaatttcaa
      601 ttaatgtatt ttatgttaat tttaataagt agtttatgtg ttattattta ttcttataaa
      661 ataacaagtt tatatatttt taaaaatttt aagataggta ttttgctagt tttttacttt
      721 ttattttctc aaattatttt tggattaata ataagtgata atcaatttga ttataagaat
      781 ttcttgaatt atattcttct tcctataata tcattagtat atatttatcc ttttttatgt
      841 gaagagtatg gttggagatc ttttttacaa agtattttat ttgatagatt tggcaaaaaa
      901 ataggtattg taatggtagg cacttgttgg agtttatggc acttaccttt acaatttaca
      961 ctatatagtc ctcaaactcc aataattgga gctatagccc atttgatata tggtattgga
     1021 ctttctatat ttttaggtta tgtttatatg aaaactaaga acatatggtt ttgctctata
     1081 atgcatgttc taattaatag cttaggatta attttcaatg attctgaaat aattattaat
     1141 taccatagta ttatacaaag attgatattt atactattat tttatactcc ttttctattt
     1201 acaaaagaat ataagtaaga attacaatta atttatataa aataaa
//
LOCUS       DAEQJM010000174         1146 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.178, whole genome shotgun sequence.
ACCESSION   DAEQJM010000174 DAEQJM010000000
VERSION     DAEQJM010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.178"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..>1146
                     /locus_tag="KRQ43_003690"
     rRNA            <1..>1146
                     /locus_tag="KRQ43_003690"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          293 a          253 c          352 g          248 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtactag gtgtcggggg ttaccccctt
      601 cggtgccgca gctaacgcat taagtactcc gcctgggaag tacgctcgca agagtgaaac
      661 tcaaaggaat tgacggggac ccgcacaagt agcggagcat gtggtttaat tcgaagcaac
      721 gcgaagaacc ttacctaagc ttgacatccc aatgacatct ccttaatcgg agagttccct
      781 tcggggacat tggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg
      841 gttaagtccc gcaacgagcg caacccttgt ctttagttgc catcattaag ttgggcactc
      901 tagagagact gccagggata acctggagga aggtggggat gacgtcaaat catcatgccc
      961 cttatgctta gggctacaca cgtgctacaa tgggtagtac agagggttgc caagccgtaa
     1021 ggtggagcta atcccttaaa gctactctca gttcggattg taggctgaaa ctcgcctaca
     1081 tgaagctgga gttactagta atcgcagatc agaatgctgc ggtgaatgcg ttcccgggtc
     1141 ttgtac
//
LOCUS       DAEQJM010000175         1114 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.179, whole genome shotgun sequence.
ACCESSION   DAEQJM010000175 DAEQJM010000000
VERSION     DAEQJM010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1114
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.179"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(303..809)
                     /locus_tag="KRQ43_003691"
     CDS             complement(303..809)
                     /locus_tag="KRQ43_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HBH2744020.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          402 a          162 c          100 g          450 t
ORIGIN      
        1 ttatttacat taaaataaat caaatacaaa tgccataaat taagtgtttc tagttagcat
       61 aaaaatactt ataaagtatg ctcaaatatt tcaaataaat acttttattc aaataaatct
      121 ctacttatat aagtgcttat ataaataaaa agatgaacta tagtaaatat agttcatctt
      181 ttttataata gtatttattt aaaattaata tttatttagt tagtagcatc tacttagata
      241 tcagataaga aagcacagtc atttacttat aataagttct tttcatatat tttttattat
      301 aattattctt ttacaagaac ttttataatt tctgaaatgt acatagtatg atagtctttc
      361 tctggatacc attttttatc attttcttta gcatcaaagt tttctggtgg catattacca
      421 tgatatagct ttttacatac tataatcata ttagcttctt caaaagctac cgtatcatcc
      481 acaaaatatg gtgtaagtcc tgctttttct attttattta tatctctacc agaaatagta
      541 ccacaaatat ttaaagcctc tctatacgtt tcatcaaaga aggcaactgt aaatgtatca
      601 ttactatcta caaattcttt tgtatatctc tgtggtctta tgtaagttgt aacaacattt
      661 ttaccccaat agactccaac accaccccag ctagcagtca ttgtgttaaa cttttctgaa
      721 tcaccagctg ttataagtaa ccattctttg ccaatcttag taaatggatt aaactgtagt
      781 tcctcaattt ttacttctct aaaacccatg acttcatcct acccttcatt ttttaattat
      841 ataaattaat tgttaaaaat ttgaatatat gtactcttat aatactgact tttgattgtc
      901 ctacataatt catgtaaatt ataatacaac aaatcaatta ctttcgcaat aagtagtttt
      961 catattttat aagtgtaaaa tatagataaa atatattgat tataaagtat ataatatatt
     1021 tttaaaccta aagcaatata caataaaaaa atgtagaaag taagtatctc tctacatttt
     1081 ttattatata ttatttttat attaatttaa tttt
//
LOCUS       DAEQJM010000176         1083 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.180, whole genome shotgun sequence.
ACCESSION   DAEQJM010000176 DAEQJM010000000
VERSION     DAEQJM010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1083
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.180"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(91..801)
                     /locus_tag="KRQ43_003692"
     CDS             complement(91..801)
                     /locus_tag="KRQ43_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2744021.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELEKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVHIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLEP"
BASE COUNT          375 a          145 c          119 g          444 t
ORIGIN      
        1 aaaattaaat ttgaaaaaac aaaactctaa aaactgagct ttaaaaaatt aagtttcaaa
       61 aataaaattc tagagattga acttcaaaaa ttaaggttct aacatatacc ttgtaaattt
      121 tcctacaacc tcttgatatt ttttacggct tataggaatt ttttcattct gaactttggc
      181 ataagtttga gttatactat ctacatggtt tagattgaca atataccttt gatgcgtacg
      241 tataaaatta gagggaagaa cagtttccat atcatttaat tttccgtagt attctaatgt
      301 tttatcaaag gtaactacag ttaattttct tagctcgctt ttaaagtaga ggatatcttt
      361 tgtattaatt ttacaaagat tagttccaat atgaactgta ataaagtttt ctttccattg
      421 ttctaatttt tttagtgctt cttttaatac tttacatatt ttttcagttt tataaggttt
      481 taagatgtag ttcaaagctc ctacatcata cccatgaaat acatagtcag aaaaacctgt
      541 gacaaagatg attatagtat cttttgaatg ttttcgtata gtttttgcta tgtcaacgcc
      601 attacttttt tcaagttcaa tatctaaaaa aataatatct atgtaataat tttcgtgttc
      661 tagattgtat actagacttt ctccatttga atattctttt atttggtagg ggtagcccca
      721 caaatccatt tctcttgtaa tgattttatt cagcatgttt ctttgttgtt tttcatcatc
      781 acaaatacaa atcgaagtca attttttatc tcctttcaag ttttatattt atatagttaa
      841 gtatataata tattttgcta cctagatata taaaatgaaa taacaattat atccagatag
      901 caaaataaaa ttttttatat tagtatactt acacttaaaa ctattctatt aaacttattc
      961 tgaagtgcta atgattttct tattaaaaaa tctaataacc tttcttatta taaaatacca
     1021 atgcttttat tattataaaa atgtaatgac ttttcatatt ataaaaagca aatgattatc
     1081 tta
//
LOCUS       DAEQJM010000177         1046 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.181, whole genome shotgun sequence.
ACCESSION   DAEQJM010000177 DAEQJM010000000
VERSION     DAEQJM010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1046
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.181"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            382..894
                     /locus_tag="KRQ43_003693"
     CDS             382..894
                     /locus_tag="KRQ43_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2744022.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEDYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKAKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
BASE COUNT          456 a           69 c          188 g          333 t
ORIGIN      
        1 gaatattcag taaaataatt ttgatatact ctatatattt tgtatgttaa aagtaaataa
       61 attattgtta aagaatgtaa agacttttaa attttttatc acaggatttt aagtaaataa
      121 gaaggattgg agtaattaaa aatttttatt ttgcaaaaat aagtatttat ttatatggat
      181 aaatttgatt ttaaatctat caatatagat aaaatcttat tatttaactt caactattcc
      241 ttaaaaaagc aacttttaag gaatagttga aacaaaaagt ttggttacat aatagtaatt
      301 ttagttacaa gaatgaaact gtaaaactta ggattttctt tatataattt cattgagaac
      361 atttaattta ggaggtaagg tatgaaagta aaaaaattta aaagtggtat agtaatggca
      421 ttaacagtaa tggcaattgg agcatcattg acaaatgtat cagctatgga attaaacaag
      481 agtaaagagt ttgaaactaa atacaatgaa atgaagaggg attttcaaga ggattatgga
      541 aaagaagaca aatttaatat aacattggat gatgaattta caaaagaaga agtaaatgga
      601 gctaaaggga ttataaagac aactaataaa atgaataatg aggttgtagt attaaattat
      661 tttgatgaaa tgaaatctgg gattgaattt gagttgaagg caaaagcaga aaaaaatgca
      721 attttgagag atgaatttca acaaggttat ggaaaggaag ataaattcaa agttgtgtta
      781 gatgatgaat ttacaaaaga agaggtaaat ggagctaagg gcattataaa gactacagat
      841 aaagagacag gtgaggttat cgtatataat tactttgatg agcttgaaaa ataatgctta
      901 aagattactt tgattgaatg aaaaggtaat tgtgttgaga atattaaatg actgaataaa
      961 aacagttgta tcaaaaacaa acaataatag aatgtaagaa tgattgtgtc gaaaatatta
     1021 aatgactgaa taaaaaatag ttgcgt
//
LOCUS       DAEQJM010000178          817 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.182, whole genome shotgun sequence.
ACCESSION   DAEQJM010000178 DAEQJM010000000
VERSION     DAEQJM010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.182"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..769
                     /locus_tag="KRQ43_003694"
     CDS             <1..769
                     /locus_tag="KRQ43_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2744023.1"
                     /translation="EDMSEVKQEMIVMKEDMSEVKQEMTVMKEDMSEVRQEINIMKED
                     ISEVRQEMTVMKEDMSEVKQEINVLKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTS
                     EVKQEINVMKKDMSEVRQEITVMKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIA
                     NEKLYGIEIKIDSLECEDKSMKEIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKG
                     DTNSIKEDIAEIRRDLNLVELATSKNWSDIVKLKSVK"
BASE COUNT          395 a           66 c          157 g          199 t
ORIGIN      
        1 agaagatatg tcggaagtaa aacaggaaat gattgtaatg aaagaagata tgtcggaagt
       61 aaaacaggaa atgactgtaa tgaaagaaga tatgtcagag gtaagacaag agataaatat
      121 aatgaaagag gatatatccg aagtaagaca agaaatgact gtaatgaaag aagatatgtc
      181 ggaagtaaaa caggagataa atgtattaaa agaagatatg tccgaagtaa gacaagagat
      241 aaatataatg aaagaagata tgtctgaagt aagacaagaa atgactgtaa tgaaagaaga
      301 tacatcagag gtaaaacaag agataaatgt aatgaaaaaa gacatgtcag aagtaagaca
      361 agaaataact gtaatgaaag aagatgtttc cgaagttaaa tcagaagtaa actttatgca
      421 aaataaaata aataacatta atgaagatat gaatggaatt aaggacgagg tatccatagc
      481 aaatgaaaaa ttatatggaa ttgaaattaa gattgatagt ctagaatgtg aagataaatc
      541 aatgaaagag atacagatag aacagaataa tattttagga agtttattac ataattctga
      601 aataaataaa gctactcatg ataatataga acataacata gcatatataa aaggtgacac
      661 taattctata aaagaggata tagctgaaat aagaagagac ttaaatttag tagagttagc
      721 cactagtaaa aattggagtg atattgtcaa actaaaatca gtaaagtagt attttaattc
      781 actaatttat catccacaaa ctaagaattt tatataa
//
LOCUS       DAEQJM010000179          800 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.183, whole genome shotgun sequence.
ACCESSION   DAEQJM010000179 DAEQJM010000000
VERSION     DAEQJM010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.183"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            490..795
                     /locus_tag="KRQ43_003695"
     CDS             490..795
                     /locus_tag="KRQ43_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2744024.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
BASE COUNT          356 a           68 c          110 g          266 t
ORIGIN      
        1 attaaaaaat gaatgattta tagattaaga agtaagctta tagattagag aataaatgac
       61 ttataaataa aaagaaagct tatagattag agaatgaatt aattataggt aaaaaacaag
      121 cttatagatt agagaataaa tgacttataa ataaaaacca agcttataga ttagagaatg
      181 aattaattat aaataaaaac caagcttata gataagaagt ccatgcttat aagccagaaa
      241 atgaatactt taatagatta aaaaatacat atttgtgaat tatagaatga ataactccat
      301 aaactagaaa atttataata atatctatat gaaaattaga attattttat cacaaaaaaa
      361 ttaagttaaa taaatatgaa attacttcca aatatacttc caaaaacatg taatcgcata
      421 tataatataa ttataaaaat aataaatatt tttatagtag tagttaatta ttaataagga
      481 ggggtcaaaa tgcctagcat gattatggaa gttgtaggag tactatttat agctattgga
      541 ttaatcttga cattcattga aataaaagga aatttccctt ctttttatgg ttttggtcaa
      601 aattctatag ggaaaaatgc tgtaggtatt atagcagcag gaattgcttt aattttcttt
      661 agaaatggca tagatagcat agattctata gctacttatg gtgtattttt agcaatagaa
      721 cttgttgtaa tagttgcata tttcttaata agaaaaaaat ttactaaaga agataaacat
      781 ttaagaacta attaactaaa
//
LOCUS       DAEQJM010000180          752 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.184, whole genome shotgun sequence.
ACCESSION   DAEQJM010000180 DAEQJM010000000
VERSION     DAEQJM010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.184"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..>752
                     /gene="tuf"
                     /locus_tag="KRQ43_003696"
     CDS             <1..>752
                     /gene="tuf"
                     /locus_tag="KRQ43_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH2744025.1"
                     /translation="ELLELVEMEVRDLLTEYDFPGDDTPIVRGSALMALEDPKSEWGD
                     KIVELFEQIDEYIPAPERDTDKPFLMPVEDVFSITGRGTVATGRVERGVLKVQDEVEL
                     VGLTEAPRKVVVTGVEMFRKLLDQAQAGDNIGALLRGVQRNEIERGQVLAKTGSVKAH
                     TKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTME
                     VDLINSIVVEEGLRFSIREGGRTVASGVVATI"
BASE COUNT          310 a           94 c          187 g          161 t
ORIGIN      
        1 gagttattag agttagtaga gatggaagta agagatttat taacagaata tgatttccca
       61 ggagatgaca ctccaatagt aagaggttca gcattaatgg cattagaaga tccaaagagc
      121 gagtggggag ataagatagt agaattattc gagcaaatag atgagtatat accagctcca
      181 gagagagata cagataagcc attcttaatg ccagtagagg atgtattctc aatcacagga
      241 agaggaacag ttgcaacagg aagagtggaa agaggagtac taaaagtaca agacgaagta
      301 gaattagtag gattaacaga agcaccaaga aaagtagtag taacaggagt agagatgttc
      361 agaaaattat tagaccaagc acaagcaggg gataatatag gagcattatt aagaggagta
      421 caaagaaacg agatagaaag aggacaagta ctagcaaaga ctggatcagt aaaggcacac
      481 acaaagttta cagcagaagt atatgtactt aaaaaagaag agggtggaag acatacacca
      541 ttctttgatg gatatagacc acaattctat ttcagaacaa cagacgtaac aggagcttgt
      601 aagttaccag aaggaataga gatggtaatg cctggagata acgtaacaat ggaagtagac
      661 ttaataaact caatagttgt agaagaggga ttaagattct caataagaga aggtggaaga
      721 acagtagctt caggagttgt tgctacaata at
//
LOCUS       DAEQJM010000181          734 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.185, whole genome shotgun sequence.
ACCESSION   DAEQJM010000181 DAEQJM010000000
VERSION     DAEQJM010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..734
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.185"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
BASE COUNT          300 a           52 c           84 g          298 t
ORIGIN      
        1 atataattta ttgaatttca ataataaatt gttgatataa tatataaaac cattataata
       61 tacactaaaa ataagaatgt ataaggtggt aaatttatat aaaaaagaat atgagttgta
      121 aaatattaaa taatattgta ctaattggaa taattttaac tttattatag attattttaa
      181 tgccattagt actgatggtg tattttaaaa ttggtataag cattacaaat acgaatatgc
      241 caactgtaat atgtaatata agtagctata tacatatgtg ctgtcccata tattgtatca
      301 ttgtttatat taaaaagatt atgtaaattg gtatcaatca ataaatcatt ttcagaagaa
      361 atacctaaaa acttaaaaaa tacctatatg tgtatttagt tagattggag atttttacat
      421 ttaattttat agtgacaata ttatattatt gttatgatgt ctatttatat gcaattacta
      481 taatatcaga acttatagta tcatttgttt cattatcaat aaggtttttt actttgtttt
      541 gtcaatttta ttaaaaaaag ttattgatat aaaagataag aaggataaaa ctatatgaca
      601 gatttcaaac ataagagtgg atatttatat aatagatatt ttatagttaa ttttattaga
      661 ttttatttaa tactgtaata ttaatatcac aatatattaa taatgtatta aagattgaat
      721 tttgtagata acta
//
LOCUS       DAEQJM010000182          723 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.186, whole genome shotgun sequence.
ACCESSION   DAEQJM010000182 DAEQJM010000000
VERSION     DAEQJM010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..723
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.186"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..>723
                     /locus_tag="KRQ43_003697"
     CDS             <1..>723
                     /locus_tag="KRQ43_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003467946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBH2744026.1"
                     /translation="KNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGD
                     STTMYPSQNISDEIKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRT
                     VPYISKVSGVPIVDLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEV
                     SLGPEMKSTGEVLGVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAK
                     DMKELGYTFVATEGTAKSLRENG"
BASE COUNT          292 a           75 c          154 g          202 t
ORIGIN      
        1 aaaaatccag tacttataga taaatatcta actggtagag aaatagaagt agatgctata
       61 tgtgataagg aagatatatt gatacctggt ataatggaac atttagaaag agctggagtt
      121 cactctggag atagtacaac aatgtatcca agtcaaaata tatctgatga aataaaagaa
      181 aagatagtag aatacactaa aaaaatagct ttagacctta atgtgcttgg tatggttaat
      241 atacaattta tagaatttca aaatgaatta tatataattg aggttaaccc tagagctagt
      301 agaacagttc catatataag taaagtaagt ggagtaccaa tagttgactt ggctactaag
      361 tgtatgttag gagctaaatt aaaggattta ggatatggta caggagttta caaagagcca
      421 aaattagtat cagtaaaagt accagtattc tcaatgtcta aattatctaa agttgaagta
      481 agtctaggac ctgaaatgaa gtctacagga gaagtcctag gtgtaggaga aaatttagaa
      541 gaagccttat ataaagggtt cttggcagca ggtagacata tgtctgatga aagaggagta
      601 gtacttgcta ctgtaaataa tcatgataaa gatgagttta tagagatagc aaaagatatg
      661 aaagaattag gatatacttt tgttgctaca gaaggaacag cgaagagttt aagagaaaat
      721 gga
//
LOCUS       DAEQJM010000183          719 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.187, whole genome shotgun sequence.
ACCESSION   DAEQJM010000183 DAEQJM010000000
VERSION     DAEQJM010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..719
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.187"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
BASE COUNT          302 a           72 c           71 g          274 t
ORIGIN      
        1 agacagtttt acatatttca actgtctcct aagaggggta tagttcacaa ctaagagtgg
       61 ctgggaactt aatataaagt tccagaaaag taaatcttca aaataattta ttgaaggaaa
      121 catcactcaa agttaagtaa aatatgtttc cttgctttta ttatatcaca aattaaaaat
      181 attaacacaa aattttgtga atatatactt attattgttc taaaaaaata tgtaaataat
      241 tgatttgatt tcatagaatt attgttgtaa tatttagtta aatatacaca atctcaatta
      301 aagaagataa gtattataaa ttcatatcaa aaaaatacat aaacttttaa gttataattt
      361 tataaaaagt cttttagtat cattatttca agaggaatta acatatgaaa aaataacttc
      421 attagaaaag tggataaaaa actggtaaga agatgactaa agattacata tactattact
      481 taaattaaaa atttaatata atttataatg tatacaattt attataaaaa atttaatttt
      541 aattttctat ttttgatact ataatatata atcttgataa tttaattaaa aatctagatt
      601 ttacatacca aactggtttc ttatttcgct atctttactt atgaactcat atattcctat
      661 aaaggttatt ttagaaaaag ttggttattt aaacattaat accacaattt ctatagatt
//
LOCUS       DAEQJM010000184          688 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.188, whole genome shotgun sequence.
ACCESSION   DAEQJM010000184 DAEQJM010000000
VERSION     DAEQJM010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.188"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(482..658)
                     /locus_tag="KRQ43_003698"
     CDS             complement(482..658)
                     /locus_tag="KRQ43_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2744027.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
BASE COUNT          256 a           65 c           97 g          270 t
ORIGIN      
        1 tataaacaaa aaataaaaaa tttatataaa taaaatgctt gtttttcttg tattatttat
       61 ataaatattg aaatttgtct agttatacgt ttttattgac cagttatgca gttgatattg
      121 aatattctaa atattggtgt tattttatag gtggtttaaa catattaggg ggattttata
      181 tatgatttgt atgatttata gagaatgtat aaaatagtaa aggtttagag catgtttagt
      241 ggattgcaga atatgcatat agaatgattc ttgtaaatta agttagacat aggaaatata
      301 taatttgtat tggatgattg attttatggt gtatgctttt aacttctata atgggaaagt
      361 aaagatgtac tcccaataca tctttacttt agcagaagtt atagttactt ataaagtaca
      421 aaaaattata tatttattag agtagataaa tctaaaaagg tttttctaga aaaatttaat
      481 tttaattgta tctacttact aataataaga cttgatgtaa gcaggtttca actaccgttt
      541 ctccatattc tgatataaaa tcatctaact gtgtatctaa aaaattacaa taatcatatg
      601 aactactgat gtaagcagtt agtatatgtg tacatttgtc tatttctcca ataaacatat
      661 tatccatccc cctaaaaaat ttagtaaa
//
LOCUS       DAEQJM010000185          672 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.189, whole genome shotgun sequence.
ACCESSION   DAEQJM010000185 DAEQJM010000000
VERSION     DAEQJM010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.189"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            68..>672
                     /locus_tag="KRQ43_003699"
     CDS             68..>672
                     /locus_tag="KRQ43_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH2744028.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNIS"
BASE COUNT          235 a           55 c           87 g          295 t
ORIGIN      
        1 attagtatgt attttttatg atatatttta taaaaaatat aatttaatca tttttgagga
       61 tattattatg ttagatgcat ttataacaat tgtttcttct attatagaaa tatggtcatg
      121 taaaaaagtt tttgattata ctagtcagtc aaagaccgac ttaaaaaaac taaatatgta
      181 ttttctcttt tctgtttttc ttattatttc ttctttatat ataaatatag gagctaatag
      241 tagaatcttg atatgtatat ttgtaatgtt cgttttctat aagtctaact ataaggttaa
      301 tatatataaa tgtctggtaa tctcattttt ttattggtta atattaatag gtataaatgg
      361 attaagtatg ttattagtag caacagtaag caatttggat aatatgaatg ttttacttag
      421 tggcagttta tatagatatg aagcaatatt cttgggaaag ataatgttag gtatattact
      481 ttatgtttat aaggcttctt ttaaaaattt taaaataagt aaaaaagaga tatacatatg
      541 tattcctatg atagcaaatt tattgtcatt ttttgtactt tatgattata ttattaatct
      601 tgtaaaaatc tctcctgaaa gaagaactgc ttttttagta atagttttac tattaatatt
      661 atctaacatt tc
//
LOCUS       DAEQJM010000186          575 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.190, whole genome shotgun sequence.
ACCESSION   DAEQJM010000186 DAEQJM010000000
VERSION     DAEQJM010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.190"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(18..>575)
                     /gene="bclA2"
                     /locus_tag="KRQ43_003700"
     CDS             complement(18..>575)
                     /gene="bclA2"
                     /locus_tag="KRQ43_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HBH2744029.1"
                     /translation="GAVGATGANGVAGPIGPTGPTGANGTTGATGATGATGANGATGP
                     TGATGATGVLAANNAQFTVSSSSLGNNTLVTFNSSFINGTNITFPTSSTINLAVGGIY
                     NVSFGIRAILSLAGFMSITTNFNGVAQNNFIAKAVNTLTSSDVSVSLSFLVDARAAAV
                     TLSFTFGSGTTGTSPAGYVSVYRIQ"
BASE COUNT          152 a          129 c          100 g          194 t
ORIGIN      
        1 tcttttcatc atataaacta ttgtattcta taaactgata catacccagc tggagaagta
       61 cctgtcgtgc ctgaaccaaa tgtaaagctt aaagtaacag ctgctgctct agcatcaact
      121 aaaaagctta aacttacact tacatctgat gaagtaagcg tatttactgc ttttgcaata
      181 aagttatttt gggctactcc attaaagtta gtagtaattg acataaatcc tgcaagtgaa
      241 agtatggcac gtataccgaa agatacattg tatatccctc caactgcaag atttatagta
      301 ctacttgttg gaaaagttat attagttcca tttataaatg atgaattaaa tgtcactaat
      361 gtattattcc ctaaacttga agaagatact gtaaattgtg cattgtttgc tgctaacact
      421 cctgttgctc cggtcgctcc tgttggacct gttgctccat ttgctcccgt tgctccggtc
      481 gcccctgttg ctccggtcgt tccatttgct cctgttggtc ctgttggacc tattggacct
      541 gctactccat ttgctcccgt tgctcctact gctcc
//
LOCUS       DAEQJM010000187          420 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.191, whole genome shotgun sequence.
ACCESSION   DAEQJM010000187 DAEQJM010000000
VERSION     DAEQJM010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.191"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            <1..>420
                     /locus_tag="KRQ43_003701"
     rRNA            <1..>420
                     /locus_tag="KRQ43_003701"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          106 a           97 c          130 g           87 t
ORIGIN      
        1 cgcctcccaa aaggtaacgg aggcgctcaa aggttctctc agtacggtcg gaaatcgtac
       61 gtagagtgta aaggcaaaag agagcttgat tgcaagacat acaggtcgag caaggatgaa
      121 aatcggactt agtgatccgg tggttctgcg tggaagggcc atcgctcaac ggataaaagc
      181 taccctgggg ataacaggct tatctccccc aagagtccac atcgacgggg aggtttggca
      241 cctcgatgtc ggctcatcac atcctggggc tgtagtaggt cccaagggtt gggctgttcg
      301 cccattaaag tggtacgcga gctgggttca gaacgtcgtg agacagttcg gtccctatcc
      361 gtcgcaggcg taggaaattt gagaagacct gtccttagta cgagaggacc gggatggacg
//
LOCUS       DAEQJM010000188          376 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.denovo.193, whole genome shotgun sequence.
ACCESSION   DAEQJM010000188 DAEQJM010000000
VERSION     DAEQJM010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.denovo.193"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            complement(<1..167)
                     /locus_tag="KRQ43_003702"
     rRNA            complement(<1..167)
                     /locus_tag="KRQ43_003702"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(277..353)
                     /locus_tag="KRQ43_003703"
     tRNA            complement(277..353)
                     /locus_tag="KRQ43_003703"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(317..319),aa:Ile,seq:cat)
BASE COUNT           94 a           90 c           76 g          116 t
ORIGIN      
        1 ttatcccgta ttagcatacc tttcggtatg ttatccgtgt gtacagggta ggttacccac
       61 gcgttactca cccgtccgcc gctctttacc gaagtaaatc gctcaacttg catgtgttag
      121 gcacgccgcc agcgttcatc ctgagccagg atcaaactct caaataaaag tttatcaggc
      181 tcagatacta ttgttatcaa aatatctggc tttatggttt gtttcttgtt tataaattaa
      241 cctactgttt aattttcaaa gttctttaaa ttattgtggt gggccatcag ggactcgaac
      301 cccagaccta ccggttatga gccgggcgct ctaaccaact gagctaatgg cccacaataa
      361 tttgtggtgc cgaaga
//
LOCUS       DAEQJM010000189        18526 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.guided.069, whole genome shotgun sequence.
ACCESSION   DAEQJM010000189 DAEQJM010000000
VERSION     DAEQJM010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18526
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.guided.069"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            91..768
                     /locus_tag="KRQ43_003704"
     CDS             91..768
                     /locus_tag="KRQ43_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2744030.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVERI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            840..2855
                     /locus_tag="KRQ43_003705"
     CDS             840..2855
                     /locus_tag="KRQ43_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH2744031.1"
                     /translation="MKKYNILKGTLIVLIVSLLAIAGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGEDKLLSLELPEIFSASEVWINGEIVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKDTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKLYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDSSY
                     FMVVLCIICINGSISKIEEDKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFIIVILFSLMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KKFLADVAHDLKAPVSAIQSFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNDFIKEIYENNLPDTQACGVNFETYILEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKVSDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            2905..3585
                     /locus_tag="KRQ43_003706"
     CDS             2905..3585
                     /locus_tag="KRQ43_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2744032.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKEISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILTDGDGWTLCKKIRNVTTCPIVYMTYINEEQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            3967..4665
                     /gene="vanR"
                     /locus_tag="KRQ43_003707"
     CDS             3967..4665
                     /gene="vanR"
                     /locus_tag="KRQ43_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HBH2744033.1"
                     /translation="MSGKILVVDDERDIADLIEVYLTNENYIVYKFYSGLDALNCINL
                     NEFDLAILDVMLPGVNGFSLCQKIREKYTYPIIMLTAKDEETDKITGLTLGADDYVTK
                     PFRPLELVARVKAQIRRYKKYSGSLQSGEELSHIFSFLGLELNTQTYECHLNGKALSL
                     TPTEFSILHVLLKNKGSVVNSENLFHAIWKDEYYNKSNNTITVHIRHLREKLGDTVDE
                     AKYIKTIWGVGYKI"
     gene            4701..5816
                     /locus_tag="KRQ43_003708"
     CDS             4701..5816
                     /locus_tag="KRQ43_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2744034.1"
                     /translation="MKKINNFTYRKLRDKYKFIKREKNTEAYLKYKLYIMLAIYTGIV
                     LVLMFMADYTFSNFSNPLVKWLKLRRDVLFFLVFIIGYITIFNFYWKKPWNYLREIIN
                     ATHTIYQQNDELVELSKPLKEIEQQMNQIKMSVLLSQQAVKEAENKKNNLVMYLAHDI
                     RTPLTSVIGYLSLLKEIPNMDNSQKSKYTEVALDKAQYLEKLINELFEITRYNSNQIK
                     INFEKVDLYYMLLQLKDEFYPLLSEKGNRAILKANESLTIKADSEKLARVFNNILKNA
                     IAYSYPNTEIIISAVHKDSKVDIAFRNYGQTIPEEQLSAIFEKFNRLDEARKSDMGGA
                     GLGLSIAKEIINLHGGDITVQSKDEVTTFTISLPTSI"
     gene            5961..6848
                     /locus_tag="KRQ43_003709"
     CDS             5961..6848
                     /locus_tag="KRQ43_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2744035.1"
                     /translation="MELKIEHVTKKFKDKIAVEDVCLTLTPGVWGFLGANGAGKTTLM
                     RIITDIMKPTNGKILYNGKNIYIMGAEYRNLLGFLPQEFGFPQDFSVKDYLEYIAALK
                     DVPPREVKGKINNLLEILTLSDVKNKKIIKLSGGMKRRVGIAQAMLNDPKILIMDEPT
                     AGLDPGERVRFRNFISEFSHNRVVLISTHIVSDIEYISTQNAIMKSGKILDVGTTDKL
                     VKKVEGKVWECLISNRDISKYEMNLRIINQRSEKNNQVSIRYLAEKSQIDNSIAVEPR
                     LEDLYLWLFPEAVYSKEGK"
     gene            6849..8084
                     /locus_tag="KRQ43_003710"
     CDS             6849..8084
                     /locus_tag="KRQ43_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2744036.1"
                     /translation="MRIFYLEIKRVLHSRRTLILLLLALVLSALMAFLPITYEGINYL
                     DNNGKVVELSGLDAIKYKKTIYANNSEISSGVVTPKKLKHALNIWKKTEEKYGKVGSE
                     DFPLDIYSKSILPIRPLLNRLPEAFANSETGFATELSEINTNDLDSFYEQCKTHLNDI
                     MKIERQTSSAQMKAQELYRKVDTPFEIYPGYSKDAFDYIIFYIFILLIICVAITAPTF
                     SGEYQTQSDSILRCTKHGHTRLAFTKILALFSIFIVMFVVCISIHLAISDLAFGTECL
                     KTSFQMLFSVISLVNINLLQAQILIAIGGLISILAMVSLTLFLSAKCKDSLTSMLIAF
                     SICLIPMGIGVSWIGYLLPPGGIGLKISLLYQMTSFNFLHLGGMSFWTPHIILFFSVI
                     EIPIFIFLAIRTYCKHQVS"
     gene            8466..9383
                     /gene="pstC"
                     /locus_tag="KRQ43_003711"
     CDS             8466..9383
                     /gene="pstC"
                     /locus_tag="KRQ43_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBH2744037.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGILSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            9385..10209
                     /gene="pstA"
                     /locus_tag="KRQ43_003712"
     CDS             9385..10209
                     /gene="pstA"
                     /locus_tag="KRQ43_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBH2744038.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVIIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            10228..10992
                     /gene="pstB"
                     /locus_tag="KRQ43_003713"
     CDS             10228..10992
                     /gene="pstB"
                     /locus_tag="KRQ43_003713"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBH2744039.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            11020..11673
                     /gene="phoU"
                     /locus_tag="KRQ43_003714"
     CDS             11020..11673
                     /gene="phoU"
                     /locus_tag="KRQ43_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBH2744040.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            11831..12700
                     /locus_tag="KRQ43_003715"
     CDS             11831..12700
                     /locus_tag="KRQ43_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH2744041.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGNYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            12787..14223
                     /locus_tag="KRQ43_003716"
     CDS             12787..14223
                     /locus_tag="KRQ43_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBH2744042.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            14271..15098
                     /locus_tag="KRQ43_003717"
     CDS             14271..15098
                     /locus_tag="KRQ43_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH2744043.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    15399..15661
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15737..18403
                     /locus_tag="KRQ43_003718"
     CDS             15737..18403
                     /locus_tag="KRQ43_003718"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBH2744044.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKAHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKVKKEKFEEMIKSVEERLTNLESKIK"
BASE COUNT         7280 a         2008 c         3324 g         5914 t
ORIGIN      
        1 actagttata tatgaaaata aaacattata atttgtaata attataaaac ttgagattat
       61 gattaaaata cctttgaatg gagtggtgta atgtataatt tactggttgt agatgatgat
      121 gttgatattt taaatataaa tcaaatttat ttttctaata taggttttaa tgtatataca
      181 tcagagactg ctaaagatgc tatggatata gtagagcgta tagttttaga ctgtataatt
      241 ttggatattt cattgccaga tatagatgga tataaaatgt gcaatgatat aaaagaaaag
      301 gttaacatac ctataatatt tttatctaat tatgagcatg aagaagaaaa agttcgggga
      361 tttttagctg ggggggatga ttatataaca aaaccttata gtttaaaaga acttgaactt
      421 agaatatatg ctcgtatgag gcagtacaaa aatattacat cagttcctaa tgtgttaaag
      481 ttttcagcgt tagtaataaa tgtaaattca agaaaagtaa cttttgatgg agaaagtata
      541 gatttaacta ctatggaatt tgaaatatta ttgtttctag ctgaaaacaa agaacaagta
      601 ttttcgaaga tagagatata taaccaagtt tggaaaatgc ctgatattgg agatcaacat
      661 acagtgcagg ttcatattgc acagatgaga aaaaaaatta attctttaag cagggagcat
      721 caatacattc aaaccgtatg gggaaaagga tataagtttg taccataagt gagatactgt
      781 aattaataaa tagttcttgt tttatttaat actactatga aagagatgtg gttgatgcaa
      841 tgaaaaagta taatatacta aaaggaactc tcattgtatt gatagtctct ctgttggcaa
      901 tagcaggatt aaatcttctg tataaatatg ataataaata tacatataag tctattagag
      961 caagtaatgg aattttaact atagataatg atactttcac taaaggtaaa cttgtctttc
     1021 tgatagatga ctgggagttt tataatcata aaatatttaa accgaatgat tttacagagc
     1081 aagatataaa accagaatat gtttttatag gtcaatatcc agatttttct atgagaaaag
     1141 ggaatcagtc accatatggg aatgctactt atcgtatgag aataaaaaat gaaggtgagg
     1201 ataagctact aagtttagag cttcctgaga ttttttccgc aagtgaagta tggataaatg
     1261 gagaaatagt ttctaaatta ggagatgtag gaacagaaaa atatagaccc aaaattaaaa
     1321 attcagtagt aagttttatt gcaaagaaag atacagaaat tataatcaat gtatcgaatt
     1381 tttcacatta ttatagtggt ttgtattatc cgcctgcatt aggagaaaca aaggacataa
     1441 gtaatatgat gttttatcga ttactttttt atagtataat ttgcttcaca acttttgcaa
     1501 tagctatatt ttcgttgtct gtatggtttc tttcaaacaa aagtaaactt tacttatatt
     1561 ttggatgtat gtgtgttttc tttgccatcc atgtatccta tccctttgta catttgttag
     1621 gactgccttt ggtaagcttt acatatgcgg ttgaagattc gtcctatttt atggtagttt
     1681 tatgtattat ttgtataaat ggaagtatat ccaaaataga agaagataaa gtgtatagat
     1741 ttttaatttt accattagga attacaatga gtatcatatc tatagtgata ccaattattc
     1801 ttcttccata tgatatgtac tttgtcaaca tatatgggaa attaatagac atatataaat
     1861 atattgtatt tatatatata ttaatgtctt cgctggtttc aatatataaa aagacatgct
     1921 ctgagcatat aagttcttat attttagttt cagtaaacac tgtttttgga attagcatat
     1981 tatttgatgc agttactagt aatagatttg agcctatatt tacagggtgg caaacagaat
     2041 attgtggatt tataattgtt attttatttt ctcttatgat gataaacagg aatagaataa
     2101 taataaaaga gaatgaaaaa cttacaagga atcttgaaca tgaagttgaa gtgagaacta
     2161 atgaacttac aacattgtta aatgaacgta aaaaattctt ggcagatgtg gcacatgatt
     2221 taaaggcacc tgtttcagct atacaatcat ttatagactt gataaaggtt ggtaatattc
     2281 atgtagatga agagacaaga acctatcttt atgctataaa tcaaaagtca aatgaagtac
     2341 aaaatagagt acgtagtttg caagaattta catcacaaga taaaagcatt ggtattagtg
     2401 aaaaaatatg tctaaatgat tttattaaag agatatatga aaataacttg ccagatacac
     2461 aagcatgtgg tgtaaacttt gaaacttaca tattggagaa aaaaatatat gcaaagataa
     2521 ataaagagat gcttacaaga gcatttgaga atttaattta taatgctttg acatttactc
     2581 catttgatgg aaagataatt ttatcaatgg ataaagaaga tggatttgca attattaaag
     2641 tttctgataa tggaaaaggt atacctccag aaaatatacc aaaggtattt gacagattct
     2701 ttacagaaag agataataat gagccaaaag ggcaagggct agggttatat attgtcaaat
     2761 ccattataag agagcatggc ggagaaatct ttgtagattc agaactagga aaaggaactg
     2821 tttttacaat aaaattaagt ctatgttttt tataataata gcttatttaa tataaaagaa
     2881 taatgatatt tgggagtgat tataatgcaa actaagatat tgataataga tggagacaag
     2941 gataattgcc agaagctaaa aggatttctg gaggaaaaag aaataagtat agatttagca
     3001 tataattgtg aagaagctat tggaaaaata tttagcaata aatatgattt aatattttta
     3061 gaaataattc taactgatgg tgatggatgg actctttgta aaaaaattag aaatgtaact
     3121 acttgtccaa ttgtttatat gacttatata aatgaagaac aaagcatttt aaatgcttta
     3181 aattctggcg gagatgatta cttaataaag cctctaaatt tagaaatatt atatgcaaaa
     3241 gtaaaagcta ttttaagaag aatgaactca tatgtaaata ataatgaaaa taatacaaaa
     3301 ttagaggaat ataatagaac tagtggagta ataaagttag aagacaaaat aataaaattg
     3361 actccaacag aaaataagct gttaaacttt tttatagaga atcctgaaaa gactctgact
     3421 actaaagaga tatatgaaca tgtatggatg aatgagtact tagaggataa ctatagtgtg
     3481 gtagttgcag tgaatggatt aagaaagaaa atagagaaag attataaaaa tcctcagaaa
     3541 attataacaa taagaggagc aggatattat tttaataaag aataataaat atattaatct
     3601 cattaataat tgttataaat gtgaaatgct aacgatatct aaactaaatt attataaaat
     3661 agctgactgt aatttaattg ataaagccta ttcttctaga ctttgccagt taaattacag
     3721 tcagttttat tatatgaaaa aatgcgtaac agaactatta ttttatagat tatatttgaa
     3781 aagatagata aattgtatat ctaaatctat atatattcat ttttatcttt aatatatgtt
     3841 aaataataaa atagttacat aataagatta agaatttctt aataaattct aatgtaaaaa
     3901 atcatataaa aaaattaaat ttagtataat atatataaat atatatagaa aggatgttta
     3961 aagtctatga gtggaaaaat tttagttgta gatgacgaac gtgatatagc tgatttaata
     4021 gaagtctacc ttacaaatga aaactatatt gtttataaat tttattctgg tcttgatgca
     4081 ctaaactgca ttaatttaaa tgaatttgac cttgcaattt tagatgttat gttgccagga
     4141 gtaaatggat tttctttatg ccaaaaaatc cgagaaaaat atacttatcc aatcattatg
     4201 ttaacagcta aggatgaaga aacagacaag attacaggct taactttagg tgcagatgat
     4261 tatgttacta aacctttccg acctttggaa cttgttgcta gagtgaaggc acagattaga
     4321 agatataaga aatacagtgg aagtttacaa tctggtgaag aactttcaca tattttttct
     4381 tttttaggtc tggaattgaa tacccaaaca tatgaatgcc atttaaatgg taaagctctt
     4441 tcacttactc caacagagtt ttctattcta catgtattat tgaaaaataa aggctctgtg
     4501 gtaaattcag aaaatctttt tcatgctatc tggaaagatg aatattacaa taaaagtaac
     4561 aatactataa cagttcatat tcgccatctt cgtgaaaaat taggtgatac tgtagatgaa
     4621 gcaaaatata taaaaacaat ttggggtgtt ggttacaaga tttgacacct atttttcttg
     4681 tcaagaaggg atgtagtatt atgaaaaaga ttaataattt tacttatagg aaactaagag
     4741 ataaatataa atttataaaa agagaaaaaa atacagaggc gtatttaaag tataaattat
     4801 atataatgtt agctatctat acaggtatag tattggtttt aatgtttatg gctgattata
     4861 cgttttcaaa tttttcaaat cctcttgtta aatggcttaa gttgagaaga gatgtattat
     4921 tttttttggt ttttataatt ggatatatca ctattttcaa tttttattgg aaaaaaccat
     4981 ggaattattt aagagaaatc atcaatgcaa cacatactat ttatcaacaa aatgatgaat
     5041 tggttgaact atctaagcca ttaaaggaaa tagagcaaca aatgaaccaa attaagatgt
     5101 ctgttttgtt aagtcaacaa gcagtgaaag aggctgaaaa taaaaagaat aaccttgtga
     5161 tgtatctagc acatgatata aggacaccac ttacttcagt tattgggtat ttgagcttat
     5221 taaaagaaat acctaatatg gataattctc aaaaatctaa gtatactgaa gttgcacttg
     5281 acaaagcaca atatttagaa aaacttatca atgaactttt tgaaataaca cgatataatt
     5341 ctaatcaaat caaaattaat ttcgaaaaag tagacctata ttatatgtta cttcaattaa
     5401 aggatgaatt ttacccattg ctgtctgaaa aaggaaatag agccattcta aaagcaaatg
     5461 aaagtttaac aataaaagca gattctgaaa aacttgcaag agtgtttaat aatatcttga
     5521 aaaatgctat tgcttacagc tatcctaata cagaaattat tatctcagcg gttcataaag
     5581 acagcaaggt agatattgct tttagaaatt atggacagac aattccagaa gaacaacttt
     5641 ctgctatatt tgaaaagttc aatcgtttag atgaagctag aaaatctgat atgggtggtg
     5701 caggtttagg gctttctata gctaaggaaa ttataaattt gcatggtggt gatattactg
     5761 ttcaaagtaa agatgaagtc acaacattta ctatatcgct tcctacatct atttagtaaa
     5821 atataaatca aatattagga ttttcttaag aaattatcta tttaatatta aaattatgag
     5881 tgtctttgtt tagtaaaata aatactaagc aagacacttt tgtttttgca ggtaagtaga
     5941 taaagagagg agtttcaaat atggaattaa aaattgaaca tgtgacaaaa aaatttaagg
     6001 ataaaattgc tgtagaagat gtttgcctta ccttaacacc aggtgtgtgg ggatttctag
     6061 gagcaaacgg agcaggtaaa actaccttga tgagaattat tacagacatt atgaaaccta
     6121 ccaatggcaa aattctgtat aatggaaaaa atatttatat aatgggtgct gagtacagaa
     6181 atttactggg atttttacca caagaatttg gtttcccaca ggatttttct gtaaaagatt
     6241 atttagaata tatagcagca ttgaaagatg taccaccaag agaagtaaaa ggaaaaatta
     6301 ataatctatt ggaaattctt acattatctg atgtaaaaaa taaaaagatt attaaattat
     6361 ctggtggaat gaaacgacga gtgggaattg cacaagccat gttaaatgac cctaaaatcc
     6421 ttataatgga tgaaccaaca gcagggcttg accctggtga gcgagtgaga tttcgtaatt
     6481 ttatttcaga attttctcat aatcgtgttg tcctaatatc tactcacatt gtatctgata
     6541 ttgagtacat atcaactcaa aatgctatta tgaaaagtgg aaaaattctt gatgtgggaa
     6601 caaccgataa actggttaag aaagtagagg gcaaagtatg ggaatgtctt atatcaaata
     6661 gagatatttc aaaatatgaa atgaatttac gtataatcaa tcagcgtagt gaaaaaaaca
     6721 atcaagtatc tattcgttac ttggcagaaa agtcacaaat tgataactct attgctgttg
     6781 aaccacgact agaagattta tatttatggt tatttccaga agcagtttat agtaaggagg
     6841 ggaaataaat gcgtattttt tatttggaaa ttaaacgagt gttgcactca cgtcgtacat
     6901 taattttatt attgttggca ttggttttat ctgcattgat ggcttttctt ccaattactt
     6961 acgagggtat caattattta gataataatg gcaaggtagt tgaattgagt ggtttagatg
     7021 ctattaaata taaaaaaaca atttatgcta ataatagtga aattagtagt ggagttgtaa
     7081 caccaaaaaa attaaagcat gctttaaata tatggaaaaa aacagaagaa aagtatggta
     7141 aagtaggtag tgaagatttc ccactagata tttattctaa aagtatttta ccaatacgcc
     7201 cattgttgaa tagacttcct gaagcatttg ctaattcaga aacaggattt gcaacagaat
     7261 tatcagaaat aaatacaaat gatttagatt ctttttatga acaatgcaaa actcatttaa
     7321 atgatattat gaagattgaa cgacaaactt ccagtgcaca aatgaaagct caagaacttt
     7381 atagaaaagt agatactcca tttgagatat acccaggtta ttctaaagat gctttcgatt
     7441 atataatatt ttacattttt atattattaa ttatatgtgt tgcaattact gcacctactt
     7501 tttctggtga gtatcagaca caatcagata gcatccttcg ttgtacgaaa catggacata
     7561 ctcgtctagc gtttactaaa atattagctc tattttctat atttatagta atgtttgttg
     7621 tatgtatttc tatccatttg gcaatttctg atttagcttt tggtactgaa tgtttgaaaa
     7681 cctcatttca aatgttgttt tctgtcatta gtctagtaaa tataaattta ctacaagcac
     7741 agattcttat agctattggt ggtctaattt caatacttgc aatggttagt ttaacattat
     7801 ttttatctgc aaaatgtaag gattctctta cttctatgct gattgctttt tctatttgct
     7861 taattcctat gggaataggt gttagttgga ttggatacct attaccacca gggggaattg
     7921 gtcttaagat tagtttatta tatcaaatga catcatttaa tttcttacac ttaggaggta
     7981 tgagtttttg gacaccacac attatactgt ttttctcagt gatagaaata cctattttta
     8041 tatttttggc tattcgtacc tattgcaaac atcaagtatc ataacaattt gatagaaata
     8101 atagtgatat aaactagagg atacgataat tatatatgta gtataaaagt taaatttagt
     8161 taacaaatct taatagcaga tataggtaat aaattataca taaactgtat tattatctat
     8221 atctgctatt ttaatataga gaaacaacag tatattgtaa agtaaatgtc aaatatagtt
     8281 ttaaaagtaa aattaatgtt aaaaaagtaa atataatttt acacttgctt aacttaatcc
     8341 taatatagat ttaacttaaa aaaagtagaa taaaagtaca ggaaatttga tgaagacgaa
     8401 ttataaaaaa ttaaattttg aatacagaac gaaaatcgat aagtatattt taatgggagg
     8461 gtattatgat agtaaaatct agattagtag gtttagaaaa aaatgacaat aatggcaata
     8521 agacaaaata cgtaattgaa aaagtagcaa aaaatatttt tctacttagt gctttagtag
     8581 cagttgcaag tttacttttg ataataggat tcgtatttta taaaggctta agaccattta
     8641 tatttgaagg atattcattt atagactttt taactggtgc agattgggtt ccttctgcca
     8701 ataaatttgg aatattatct atgatagtag catcaatatt tgcaacactt ggagcacttg
     8761 tgataggagt acctgttggt atattaacct ctgtatttat agcagaagta gcacctaaaa
     8821 gattagcaaa aataatgtca ccagcagttg aacttttagc aggtatacct tcagtattat
     8881 atggtgtatt tggtcttgca gtgatagttc caactataca aagtatattt aatcttccaa
     8941 aaggtcaaag tttgttagca atagtaatag tattagcagt aatgatgtta ccaacaataa
     9001 tatctgtatc agaaacagca ataagagcag taccaaaagc atacaaagaa ggttcattag
     9061 cacttggtgc atcaaaaata gaaacaatat tcaaagttgt actacctgct gcgaaatctg
     9121 gagtattagc tgcagtagta ttaggagtag gaagagcttt aggtgaaaca atggcagtaa
     9181 tacttgttgc aggaaactca ccagttatgc caactgcaat aacagatagt gtaagaccac
     9241 ttacaactaa tatagcactt gaaatgggat acgcatttgg tacacatcaa gaaatgttat
     9301 ttgcaactgg agtagtattg tttacattta tattaatttt aaacttagtt ttaaataaac
     9361 tttcaaataa ggcggtaaat taagatgaga aagttcaaag agaatctatt gaagtcatta
     9421 gtatatctat cagcactatt tacaatagta tcattagtca ttatagtggg atttatattt
     9481 ataaagggaa ttggcaacat gaattttaat ttcttattta gcaattattc agcatcaggt
     9541 gatggtggta tacttccaat gataattaca acattatata cagtagtagt ttctatagtt
     9601 gtagcaactc ctataggaat attggctgct atatatttac aagaatatgc taaaaaagga
     9661 aaagcagtta cagctataag atttgcaact gaaagtttat cagggatacc atctatagta
     9721 tatggattat ttggaggaat tttctttgta gttacattaa aaatgggata ttccatagtt
     9781 gcaggttcac ttacagttgc aataataata ttaccagtaa taattcgtac aacagaagaa
     9841 gctttaaaaa cagttcctca agcttataga gaatcatcat tggcattagg agctacaaaa
     9901 tttcaaactt tatataaggt agtacttcca agtgcaatac caggaatctt atctggagta
     9961 atcttatcag ttggtcgtat aattggagaa tcagctgcaa tattacttac agcaggtact
    10021 gtagccaaga tgccaggtgg aatatttgat agtgcaagaa cattaactgt acactcatac
    10081 ttactgacta aagagagtgg agatatagca acagcagcca gtataggaat tgttttaata
    10141 gtaattgtat tagcactaaa catgctagca agatttgttg ctaagaaatt aaataaagct
    10201 aattattaaa tttaagaggt gtgaataatg gaattaatcg ataagataaa aatgagtgta
    10261 aaagatttgg atttatttta tggtgataag caagcattaa agaaaataaa tatggatata
    10321 aaagagaata aggttactgc tttaataggt ccatctggat gcggaaaatc aacttttata
    10381 agaacgttaa atagaatgaa tgacttaatc gaagatgtaa caattaaagg aaacatttct
    10441 gttgatggag aggacatata tacctcagat gatgttataa atcttcgtac taaagtagga
    10501 atggtatttc aaaaaccaaa tccatttcct atgagtatat atgataatgt ggcatatggt
    10561 cctcgtacac atggactaag agataagaag caattagata aaattgtaga agaaagctta
    10621 aaaggtgcag ctatttggga tgaggttaaa gacaggctta aatcatctgc actaggactt
    10681 tctggtggtc aacaacagcg tatatgtata gcaagagcaa ttgctatgag accagaagtt
    10741 attcttatgg atgaacctac atctgcttta gacccaattt caacattaaa agtagaggaa
    10801 cttatagagg atttaaaaaa agactacaca atagtcatag ttacacataa tatgcaacaa
    10861 gctgctcgta tatcagatga aacagctttt ttcttaaatg gagaggttat agaatttagc
    10921 gatacaaaaa ctatgtttac cactcctgta gataaaagaa cagaagacta tataacaggt
    10981 agatttggtt aaaatatata actataaagg agttagacaa tggtcaataa tagtttagat
    11041 ataagtattg atactttaaa agaacaaaca gtacttatga tggaaaaatg tgaagaagca
    11101 atagaaaagt ctgtgacttg tatgatagag aaggatttag agggtgcaag aaaagtagta
    11161 gaagatgatg aagaaataaa taaattaaga gaagaaataa gagataagag tatagagcta
    11221 atagtattaa agcaaccaat ggcaagggac ttaagattta tttattcatt aggtaatata
    11281 tcgatagagt tggaaagaat aggagattat gcagcaaata tagctagaga aatgttgaag
    11341 ataggtggag aggcttatat aaaagagctg atagatattc ctaagatggc aaaagaatgt
    11401 aagtctatga tgtctcagac tagagaagct ttaatcttat ttgatgcaag tatagcttat
    11461 gatgttggaa ctaaagatga tattgtagat ggattgtatg aacaagtaca aattgattgt
    11521 ttaaaaataa tgcatgaaaa ttcaaatact atagaccaag gagtaaaact tctacttata
    11581 ggaagatacc ttgaaagaat tggagaccat ataacaaatg tatgtgagaa gataattttt
    11641 gcaattgagg gtaaaatggt tgagatagga taaaaaactg ctttaaagca gtttttttat
    11701 tgtctaaatt aagaaagaat tgataaaaaa atatgattaa tgggtaaatt taaaaaattg
    11761 tgatatacta ggaacatatt aaatatgagg atgcgtattt tatataaggt gctttttagg
    11821 aggtggaact ttgaaacttc aaaagatggg tatgaggact ataaaaacag gaattagtgt
    11881 cactttatgt atgattcttg gtaactatct agtagagaat atgttttatt ctctagtagc
    11941 atgtataatt tctgttcaag atacggtaaa aggttcttta aagacaggaa tcaatagagt
    12001 ggaaggtact attttaggtg gtataatagg attcatattt gccatcatta aagctggaga
    12061 ccctttttta tgtggtctag gagtaatgtg ctcaatatat ttatgcaatc tgtttaaaat
    12121 aaagtcagta gtagttgcct gtgtaacctt tctggctata catctaggtg taggaaatag
    12181 tgaccctgtg tattattctt tacatagagt gttagataca tctgtaggtg ttttgtttgg
    12241 agtacttgtt aattattatg tggctagacc aaattatcta aatagtgtta tagatgaatt
    12301 taaaaagata gaagaacttt caatgttact tattgaagat aaaattctta gaaaagaaaa
    12361 tttaaatgta gagaaatttg aagaagaagt agaaaaatta gaagaaatat attcaaaact
    12421 tattgatgag ttggattata gtttgagtga aactaatata gaaaaaattg agaatgcctt
    12481 aaggatatgt agagaaatac attttcatat gcagtctata gagttacttg aaaataaact
    12541 ttatttgaaa gagcatacat ataaatacct taagaaaaca tataatgtgg ataagctaga
    12601 ctggaatata gatgaagaaa aaagccccgt attcaactat catctaatga aaataatgat
    12661 tgaaatagag ttgttgagaa agctaaataa atcatattaa taatagtagt taaataataa
    12721 ataaaaaata gtatctttgt aaatattaaa catatataag tttaatttat ggaggtacta
    12781 ttttttatga atactagaaa tgacaattct aaaatactag aaatatataa aatgaagctt
    12841 tttggcgaac ttgtaaaagc agtgtggaat gatgatatag aggatattga aaacttacct
    12901 aataaaattt taaatgaaga tttaaaggat aatttaaata attattttag tggaaaattt
    12961 gataaagata ctatggtaaa tttaattagg gtaactatgg gattggatgt gacagaagat
    13021 acagataaaa atttaaaaga gtcactacat gaagctgtaa atttagatga agtcaaaaga
    13081 ccaataatat ctgtaatatc agatgcttgc aaatattgtg atgaaaataa taaggaagat
    13141 gagtcatgta agataagaag taagcatatt aattgtaatg aggaagatgt atgtagtgct
    13201 tgtggtgatt gtgtatcaag atgtaagttg ggtgcaattt cagataaaat agaatttata
    13261 ccaatgataa aattgttaaa agatataaag agccctgtat atgcaatagt tgcaccagct
    13321 tttgtaggac agtttgggaa agatgtaagc cctggtaaat taagaactgc attaaaaaag
    13381 ataggatttg aagatatgat agaagttgct ttggcagcag atatgcttac tgcaaaagaa
    13441 gcatatgatt attatgagca tatgaaaaag gacgaagaag gatgctttat aactagttgt
    13501 tgctgtccta tttgggttag tttgatacaa aatagttttc ctcagatatt ggagaatgta
    13561 tcaccatccg tttctcctat gattgcttgt gggagagctg taaaaatttt aaatccagat
    13621 gctaaagttg tattcatagg tccttgtatg gcaaaaaaga aagaagcaat gttagaagat
    13681 ataaaagatg cagttgattt tgtgcttaca tttaaagagt tgcaagaaat atttgatgca
    13741 ttagagttaa atccagcaat aatggatgag agtaatagag tagaggcgtc cctttcaggt
    13801 agagtttatg ctagaacagg aggtgtaagt aaagcagtta agttatcagt cagaagaatt
    13861 gacaaaaata taaaatttga agaaaaggca tttgaaggaa caaaagagtg catggacggt
    13921 ctaaagaaag ttctaaataa agaaatagaa gctacattta tagaaggaat ggggtgtgta
    13981 ggaggctgtg taggaggtcc gaagcgtatt ttaagtgtgg aagaaggtac taagaatgtt
    14041 gatgaatata gtgaaagtac gaatatggaa actccatttg ataatttaaa tgtattacaa
    14101 tttttaactt ctttgggaat caaaagagta gaatctttag gagaaaaaga agaagaaaag
    14161 gttaaaaaaa tatttagtag agatataaaa agtaataaga aagagaataa atataaaaaa
    14221 taacttttta agtcttaaac ttatgctttt ataaaaggga gatatggggg atgaaaatta
    14281 aagataataa ggctgttttt catgtattta taaggatatt tcttatagct gttttaattt
    14341 taactggaac attattggag gaaaaaatta ataatgttcc agttgaaaat ataagttcaa
    14401 aaggtgaaaa tacactggaa ctgctttctc aaagtaatac tttaggagaa atcatataca
    14461 aagcatctca agaagaaaca aaaggtccag gggctacttc tgaaaaagta gcatacataa
    14521 caatagatga tggtccatca aaatatacaa atgcactact tgatatttta aaagaaaatg
    14581 atgtcaaagc gacatttttt atgcttaatc aaaatatgaa aaatcacaag gaagaagtaa
    14641 ggagagtctt ggaagaggaa aactcaatag gttttcatag tgtaagtcat gatatacata
    14701 agttatataa aagcccagaa gtaacagttg gggaatttaa tacatgcaat aatactctac
    14761 aagaaataac tggtcagagt tcaaaattaa taagattacc atacggaagt aaaccatata
    14821 tgccagaagg ttcatataat aaacttatgg caaatgatta tttaatttgg gactggaatt
    14881 tggatacaca ggattggaag tcttctacaa gtcagatagt aagtaatata ttatattatg
    14941 gaagaaaaag agatgaatta gtagtattaa ttcatgagaa agagcaaagt ttaaatgctt
    15001 taaataatat tataagaatc ttaaaagaga gaggatatac aatattgcca attacagaaa
    15061 atataacacc taaaaatttc tggcaagaaa acttataata aatttaaata tagtaaaaga
    15121 taaagtaaat tatttataaa ataaaacata taatataaaa aatacgaata agaggtatac
    15181 tgtaaggata atataatata aaattaatga gaaagcatta aaattaaaat aaaataatct
    15241 tgcaattatt gacattataa gacagaataa ctgtaaaaac atattttaaa atataacaac
    15301 tatataaaag agaatagaca taattaagaa aattcagaaa aaataaaata aaaataattg
    15361 acaaagagaa taatatttgt atataataat atgtaatatt aaagactgag aagaagagga
    15421 gtaagtaaat actactaaaa gagaggaaaa ttcactggct gtaagatttt ctaagtataa
    15481 gatttactga atgtagcttt ggagtttcta aactgaacta taagtaagtt tagacggtta
    15541 gaaccgttaa attctttgag agtcaaagtt gataaaataa cattaactaa taatttaatt
    15601 atatgttaat gtattttaag ctttggaatt aaggtggtaa cgcgagcttt tcgtcctttt
    15661 taaagaggat gaagagctct tttttatttc taaagatatt taaaaaattt atttataaaa
    15721 tacaggaggc aggacaatgg aaaatacgaa tttatcaaaa acttataacc caaaagattt
    15781 tgaggctagg ctatataaaa aatggatgga tgaagggtat tttaaatcta aaccaaatcc
    15841 agataaaaaa ccatttacaa taatgatgcc accaccaaat ataacagggc aattgcatat
    15901 gggacacgct cttgaccata cacttcaaga tatattaatc agatggaaac gtatggatgg
    15961 atatgaagct ttttggcttc caggaactga ccatgcttct atagcaacag aagttaaagt
    16021 tgttgaaaga ataaaaaaac aagaaggcaa gacaaagtat gaaataggta gagaagaatt
    16081 tttaaagaga gcctgggaat ggaaagatga atttggagga aaaatatcta atcagcttaa
    16141 acaactaggt gattcttgtg attgggataa agaaagattt actatggatg aagggtgtaa
    16201 tgaagcagtt atagaatttt ttgtaagcct atatgaaaaa ggtcacatat acagaggaaa
    16261 tagaataata aactggtgcc cagattgcaa aactacttta tcagatgcag aagttgaaca
    16321 tgaagaacac gacggaaact tttatcatat aaagtaccca ctaaaagata gtgaagactt
    16381 tttagaaata gctacaacta gacctgagac aatgatagga gatactggta tagcagtaaa
    16441 tccagaagat gatagatata aacatttaat aggaaaaaca gcaatacttc cattagtagg
    16501 aagagaactt ccaatagttg cagatagtta tgttgattta gagtttggaa ctggtgcagt
    16561 taagatgact ccagcacatg accctaatga ttttgaagta ggattaagac ataatcttga
    16621 gcagttaaat actatgaatg aagatggaac tatgaatgaa gtttgtggaa aatatgaagg
    16681 tatggataga tttgagtgta gaaaagctat cgtagcagac ttaaaagaac aaggttacct
    16741 aattaagata aaagcgcata atcataatgt aggaacttgt tatagatgcc atacagtagt
    16801 tgagcctaga ttatcagagc aatggtttgt taagatggaa gaacttgcaa aaccagctat
    16861 agatattctt aaaaaaggag aattagaatt tgttccagat aaatttgata aaacttattt
    16921 acaatggcta gaaaatataa gagattggtg tatatcaaga caattatggt ggggtcatca
    16981 aataccagct tattattgtc aagagtgtgg agaaatagta gttgctagaa aaatgccaga
    17041 taagtgtcct aaatgtggaa gcactcattt taaacaagat gaagatgcct tagatacttg
    17101 gttcagttct gcattatggc ctttctctac tctaggatgg ccaaataaga ctgaagcttt
    17161 agattattat tatccaacaa gtgtacttgt tacaggatac gatataatat tcttctgggt
    17221 agttagaatg gcatttgcag gtatgttctg tatgaatgaa aagccatttg accatgtttt
    17281 ggttcatgga ttagtaagag attctcaagg tagaaaaatg agtaaatctt taggaaatgg
    17341 tatagaccca ttggagataa tcgagcaata tggagctgat gccctaagat ttacattaac
    17401 aactggaaat tccccaggaa atgatatgag attctatatg gaaagagtag aatttgctag
    17461 aaactttgca aataagttgt ggaatgcatc aagatttgta tttatgaata ttgatgaaga
    17521 tataattaaa aacatgacta gagaaagtgt taaagaggac ttaactctag ctgataaatg
    17581 gataatatca agagcaaata atattgtaaa agaagcaact aataacatgg ataagtttga
    17641 tttaggaata gcacttcaaa agatatacga ttttacttgg tcagaatact gtgactggta
    17701 tattgaaatg gttaaaccta gattatatgg ggaagatgca aatgctaaat ctgcagcatt
    17761 atatacatta acttatgttc ttgaaaaaat attaaaatta ttacatccat acatgccatt
    17821 tataacagag gaaatatata ctcatcttcc tactgttgaa ggatgtataa tagtatctga
    17881 atggccaaaa tataatgaag aagataacat ggctgaagaa gaagatatga tgaacttatt
    17941 gatggaaggt ataagaagta taagaaatgt gagagcagaa atgaatgtac caccttctaa
    18001 gaaagctaaa ttgataataa tcccaagtga agaaaaaata gaagctattg agcttggtaa
    18061 agactatttt ataactctag catctgcttc aaatgtagag atagcaaaag ataaatctaa
    18121 tgttccagaa gatgcagttg gagtagttat tgatggtgtt gaaatattta tacctcttaa
    18181 tgaattagtt gattttgaaa aagaaattga gagattgtct aaagaaaaga aaaagttaga
    18241 aggcgaaata aagagagtta atggaaagct tgcaaatcaa ggtttcttag caaaagctcc
    18301 tgaaagttta attgaagaag aaaaagtaaa aaaagaaaaa tttgaagaga tgattaaatc
    18361 tgttgaggaa agattaacaa atttagaatc taaaataaaa taaatataag aattagtaaa
    18421 aacatacaaa aagtatatat tctatacttt ttgtatgttt ttctttatat atatacaaat
    18481 atgatgttat aattctttac agatgtgtta tatttttatt ttatgt
//
LOCUS       DAEQJM010000190        11166 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.guided.098, whole genome shotgun sequence.
ACCESSION   DAEQJM010000190 DAEQJM010000000
VERSION     DAEQJM010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11166
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.guided.098"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            247..864
                     /locus_tag="KRQ43_003719"
     CDS             247..864
                     /locus_tag="KRQ43_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH2744045.1"
                     /translation="MCKKTYLLVVSILIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIITPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            972..3503
                     /locus_tag="KRQ43_003720"
     CDS             972..3503
                     /locus_tag="KRQ43_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH2744046.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVKEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3937..4638
                     /gene="vanR"
                     /locus_tag="KRQ43_003721"
     CDS             3937..4638
                     /gene="vanR"
                     /locus_tag="KRQ43_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HBH2744047.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KDLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4688..5770
                     /locus_tag="KRQ43_003722"
     CDS             4688..5770
                     /locus_tag="KRQ43_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH2744048.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            6031..7131
                     /gene="vanG"
                     /locus_tag="KRQ43_003723"
     CDS             6031..7131
                     /gene="vanG"
                     /locus_tag="KRQ43_003723"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBH2744049.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7128..7934
                     /locus_tag="KRQ43_003724"
     CDS             7128..7934
                     /locus_tag="KRQ43_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH2744050.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7952..10090
                     /gene="vanT"
                     /locus_tag="KRQ43_003725"
     CDS             7952..10090
                     /gene="vanT"
                     /locus_tag="KRQ43_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH2744051.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10404..11024
                     /locus_tag="KRQ43_003726"
     CDS             10404..11024
                     /locus_tag="KRQ43_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH2744052.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
BASE COUNT         4232 a         1163 c         1989 g         3782 t
ORIGIN      
        1 tcaaaatgaa ctttttagtt catgaggcac tctttttgta cgaaataaaa tatattttta
       61 ttatttcaac aatgaaaaag atgcttgttt ctattttgag acagtataat ttttatgtaa
      121 ctttaatttt agtaaatata aagttttaaa attgataaaa taggaggaat ttttaatata
      181 aaagggtaaa taaagggttt agagggcata atatagaata aattaatata tttaaggagg
      241 atttttatgt gtaaaaaaac gtatttatta gtggtaagta tacttatagc aggtttatta
      301 actgcatgta gtgggagccc aactaaggat tcaggacaag cacaagataa tacaaaaaag
      361 gaggcaaatg cttcaaataa tgctttaaaa gatgaaaaaa ataatgaaaa tttaatggaa
      421 caagatttta aagtgccata cacagatgca ataaacatat ttaaagataa atacaaggat
      481 gctgatatag tagatttaag tcttgagaga gatttaaata aatttgttta tactgtggaa
      541 ggtgtagatg ataataatga atataagatg aaaattgatg ctaatacaaa agatgtatta
      601 gaagataaaa cagaaaagtt agattcagaa gatttaaatg gagttgctag aaaagaaaaa
      661 ttagatttaa atgacataat tacacctcaa caagctatgg aaattgcatt aaaagaacaa
      721 aatggaatgg ttaaagaatg gagtttagac aaagatttag atgttacttt ttataaaata
      781 agaatagata aagataaaaa tgaatatgac ataaaagtag attctaaaaa gggaactgta
      841 ttgaaggtag aaaaagaaga ttagaagatt taaactatct ttaaaataat ttcttttttg
      901 aataaatttt gtttaaaata taacaagcag ggtataaaga gactaaataa ctattttagg
      961 aggagtacgg tatgtcattg aaatcactaa aaataaaaga aaatttatat tgggtaggtt
     1021 cacttgaccc tgatttaaga gtatttgaca taattatgta tacaccttat ggaactactt
     1081 ataattcata tgtattaaaa ggaacagaaa aaacagtttt gtttgagaca gttaaagata
     1141 agcattttga caattatatt gaaagattaa atgatttaaa tatagatttt gaaaaaatag
     1201 actatattgt tgtaagtcat actgaaccag accatgcagg aagcgttgaa aagcttttgg
     1261 atttagctaa aaatgcaaaa gtagtagctt cagaaacagc aattaaatat cttaaggaaa
     1321 tcgtaaacaa agactttgaa tatgttgcag ttacagatgg agatacatta tcaattgggg
     1381 acaaaacttt agaatttttc tctgtaccta tgcttcattg gccagatact atatacacat
     1441 atataaaaga ggataaaact cttgtaacat gtgattcatt tggtagtcac tatagtaatg
     1501 ataagatagt aaatacactt gatgaaaatg aagaaaagga ttacttggat gctttaagat
     1561 actattatga ttgtataatg ggtccattta aaccatctat ggtaactgct atagaaaaga
     1621 taaaagattt agatatagat actgtatgtc caggtcatgg tccagtatta actgaaaatc
     1681 ctagaaaaat tatagacctt tattataact ggagtgtaaa ggaacaaata aagttagaaa
     1741 aagaagttac aatttgttat gtttctgcac atggatatac aaagattatg gcagaagcta
     1801 taaaagcata tattgaaaaa aatagcaact ataaagtaaa tttatttgat gtaatagagc
     1861 ataagcaaga agatattttg gcaaaaatag cagtatcaca aggtgtatta tttggaacac
     1921 caacaatatt aggagatgcg ttaaagccta tatgggatat attaatatcg ttaaacccag
     1981 ttcttcatgg tggaaaagtt gcttcagtat ttggttcata tggatggagt ggagaaggta
     2041 tagaaaatgc tatggagaga ataagtcagc ttagaatgac agcagtaaaa ccttttgctg
     2101 ttaactttaa accatcaaat gaagagattg ataaattaca ttcttataca ggtaaattcc
     2161 tagataagtt aaattctact tttggaagta aaaagaaaac taagaaattt aaatgtgtaa
     2221 tttgtaatga agtttttgaa ggtgatagtg ctcctagtgt atgccctgta tgtggagcta
     2281 aggaagacca atttatagaa gttgaagaag atgaagttac ttttagaaaa gatactgatg
     2341 aatatttcgt aatagtagga aatggagcag ctggttttta tgcagcagat gctataagaa
     2401 aaagaaataa aacttgtaag ataactatga tttctaatga agatgagttg acttactata
     2461 gacctgcact ttctgatggt ataaatgaag aacttggttc agatttctac atggaagata
     2521 aagattggta tgataaaaat aatatagtag taatattagg aacgaatgta gataaattag
     2581 atgaagtgaa taaaactatt atagtgaatg atggagctat taaatttgat aagcttgtaa
     2641 tagctacagg aagtagaaac tttataccac cgattaaggg ccatgattta gaaaatgtgt
     2701 ttactcttag aaatataaaa gatttatata gtgtaaaaga agcactagaa aaatctaaga
     2761 aagttgtagt gattggtggc ggtttattgg gacttgaagc tgcatgggaa tttagactaa
     2821 aaggattaga agtagtagta gttgaagcca tggatagcat actatcaaaa caacttgata
     2881 aagagggtag taaaatatta gaacaatgtg taagagatac aggaatagat gtaagattgg
     2941 gtgtagcagt tgatggtatt gaaggtgatg gaaaagctca aaaagttgta tttaaagatg
     3001 gagatagtgt tgactgtgat atggtagtat tttcaattgg tgtaagagca aacactcaaa
     3061 tggttcagga tacatctgta aaaattgata gaggtattgt tgtagataag acattacaga
     3121 caaatgttaa agatatatat gcttgtggag atgttgcaca agtgggaaat attagtttag
     3181 caatatggcc atcttcagta gaaatgggaa aaatagcagg agcaaatgca agtggagata
     3241 atttgacatt tgaaagtgaa gtatatccag tttcattaga tgcaatgaat gtaaaagtat
     3301 ttagtattgg taatatacaa aattttgata aagaaatttc atcaaaagat gaaggtcaaa
     3361 gaatatataa aaaattattt atgaaagatg gttcattagt tggagctata cttataaatg
     3421 atttaagctg tactgttaaa ttgataagat taatatctga aaaaggtgat tttgaggata
     3481 ttatgaaggc tgatatacta taatttaaat acattaaaat aaaaaggagt tgtctcaaaa
     3541 ttgatttttt tctaatcaaa ttttaaattc aactcctttt ttgaattttt atataaaata
     3601 acatggaaat tttagtaatg tctgtggtta catacatagg tttaattgtt ttttatatgg
     3661 attgtctctg gtataataaa ttgaattgtg tttgactgat agatattttt attgaaagtt
     3721 aatacctgtt atgcgataat aaggacgtgt taggggagtt tttataataa caattaatct
     3781 cagtttttgt gttccaatag tagcatcaac acattctgat gtagtagttc ttttcttata
     3841 aaaattagtt acaaatatgc ttgtaattat ttgatatgta aatttaccaa tattataaat
     3901 gatgacctcg ataataagga gagtgaaaaa taatctatga acgaaaatat tttgattgtg
     3961 gatgatgaaa aagaaatagc agatttaatt gaagtatatt taaaaaatga aggttttaca
     4021 gtatacaagt tttatacagg taaggaagct ctagaatgta ttgaatctaa agatttggat
     4081 atggctattt tagatattat gcttcctgat attgatggat ttcatatttg ccagaaaatt
     4141 cgagaaaaat actattatcc tatcattatg ttaacagcta aaattgaaga tatagacaag
     4201 ataatgggtt taaccatagg tgctgatgat tatataacaa agccatttaa ccctttggaa
     4261 gttgttgcaa gagtaaagac acaattaaga agatatatgc gatataataa ttcttatgaa
     4321 caacagtcga taattgttaa tgagtatgat attaaaggat tgattatcaa taaagaaaca
     4381 cataaatgta gtttatttgg gaaagaagta gcattaacac cgattgaatt ttctattctt
     4441 tggtatttat gtgaacatca aggaaaagtg gttccttctg aagaattgtt tgaagctgta
     4501 tggggagaaa aatatcttga taataataac acagttatgg ctcatatagg gcgattacgt
     4561 gaaaaaattc atgaaccttc taaaaacccg aaatttataa aaactgtatg gggagtaggt
     4621 tatacaattg aaaagtaaaa atattaaagt caatcctgac tttactcaag tgagaaataa
     4681 aatttttatg agaacagctt taatggcatt tatagccatt attttcatat ggattttata
     4741 ttcttttata ttgtatggta agttttctat ctggatagta tcattctttg aaaatgcttt
     4801 tcgtatggaa tataaagctg cattgaattt atatcagcag attttccgta atagcatgga
     4861 gctcttcatg atactagcta tggtgattgt gttttttata atattccgtg tttatttaaa
     4921 ttggtttaca aaatatttta gtgaaataaa tcaaggtatt gactctctta tcaaagaaga
     4981 tgttggagaa gtggctttat ctccagagtt attggcaata gaaaagaaaa taaactcaat
     5041 taaacatata cttgaacaac gtaaatttga gacacaaatg gcagaacaac gtaagaatga
     5101 acttattgtt tatcttgcac atgatttaaa aacaccactt acatcagtta tagggtatct
     5161 gacactactt cgagatgaaa gtcagatttc tgaagaactg cgaaaaaaat atttatctat
     5221 ttcgttggat aaggcagagc gtcttgaaga tttaattaat gaattctttg aaattacaag
     5281 gtttaattta tcaaatatat cacttgaata cagtacagta agcttaactc gtatgcttga
     5341 acaactaaca tatgagttta aacctacttt gatgagtaag aatttaaaat atacactgaa
     5401 tgttacacca aatatgatga taaggtgtga tgttaataaa atgcaacgtg tatttgataa
     5461 cttattacga aatgctgttt attatagttt tgaagatact actattgaaa taacagctgt
     5521 acaggaggat gattatataa agcttaaatt tataaatcat agcaatacga ttccagagga
     5581 aaaacttgag cgtatttttg aacaatttta caggttggat acatctcgta attcaaacag
     5641 tggtagagct gggttgggac ttgctatagc taaagaaata gtggagcttc ataacgggac
     5701 aataacagct catagcgaga acaatataat tacctttaag gttattattc cgattgtagg
     5761 aaatttgtaa gaatttaagt ataaaaaaat aggaaattct ttaggataaa taaataaaga
     5821 gcactcttgt tattgatata attactgtat caaaacaaga gtgcttttat tttgatacag
     5881 taattatatc aatagaaaaa tgtgaaaata tattatgtgg aacagatgca attgtaagtg
     5941 aaggttgatt ggatttgaaa tagaaaaagt attttaacat gtttctgtag attgtataaa
     6001 aataaataaa tcaacaaagg agaatcaaag atgaataata aaaaaattgc agttatattt
     6061 ggtggaaact caacagaata tgatgtatca ttacaatcag cttttgcagt acttgagaat
     6121 ttgaatacgg aaaaatatga tattatacca attggaatta caagggaggg taattggtat
     6181 cattatattg gagattataa taatatccag aataacactt ggtttgaaag ggatactgat
     6241 ataattccag ttattgtttc gcagaaccgt gtcaaaaatg gtattattga atttttaatt
     6301 cctgatgctg tttctcagaa tcatattcca aatagtgcta ttgaatcatg tgaaaatgat
     6361 attaaataca ctaaacttga ttttgtattt cctgtattgc atggaaaaaa tggagaagat
     6421 ggaacagtgc aggggttatt tgaattggca ggtatacagg ttattggatg tggtactctt
     6481 tcttcagcat tatgtatgga caaagacaaa tcacataaac ttgttcattc agaaggtatt
     6541 aaagtaccaa aatcaatatt actaaaatac tcagataaat ttaatgtggc tgaactgtca
     6601 aaagacttaa cttatccatt atttataaaa cctgtgcgtg caggttcatc atttggtatt
     6661 agtaaaattt ataaaaaaga agagttacaa gtagcagtag acttggcttt tgaacatgat
     6721 aatgaagtaa taattgagga aaatattgat ggttttgagg tagggtgtgc agttttagga
     6781 aacgatgact tacttgttgg aagagtagat gaaatagaat tgtcaaaagg attttttgat
     6841 tatacagaaa aatatacatt gaaaagttca aaaattcata tgccagctag aattgatttg
     6901 gattgtgaga aaagaataca agagacagca aaaattattt atagaactct tggatgttct
     6961 ggatttgcta gagtagatat gtttttaact ccatctggtg aaattatttt taatgaagtc
     7021 aatacaattc ctggctttac ttctcatagt cgttatccga atatgatgaa aggtattgga
     7081 ctgtcttttg aagaaatatt ggataagata attgaggtgt acataaaatg atgaataata
     7141 ttttattaga taaaaataaa gaagataaaa tgacaaatac tatcttattg actaaagata
     7201 aagtttatga tgggaatcta attctagtaa atgctttttt accagttaaa acatctgaag
     7261 atatagattt aattcctgta gatacaaggt ttccaagtat tcttatgaaa cgtgaagcta
     7321 caaatatttt acaaaatatt ttaaaaagta tatgtggaat aaatgaaata gtacctgtaa
     7381 gtggatatcg tactgcagag gaacaacaag atatatattc aagctctctg cgtgacaatg
     7441 gaaaagactt tactaaaaag tttgtagcac ttccaaatca cagtgaacat cagacagggc
     7501 ttgctattga tttagggttg aagaaagagg ttatagattt tatctgccct gaatttcctt
     7561 ataatggtat ttgtaatgag ttccgtaagg cagcactaca ttatggtttt atagagcgtt
     7621 atcagtgtaa aaaagaagaa ataacaggaa tatctcaaga accatggcat tttcgttatg
     7681 tcggatatcc acattctgag attatcaata aaatgaatct cgcccttgaa gaatatatag
     7741 aatatattaa gagattttcg tatacaaatt gtttaaaaat agaagataaa gaaaaaatta
     7801 tagaaatctt ttatgtgcct attcatacta aagaagaagt gagaatctct atacctgaac
     7861 aatgtgtata tcaaatatcg ggtaacaata aggatggttt tattgtgaca ttttggagaa
     7921 atagaaagga ctaagaaatg gaggaacaag aatgattagg aataaatctt atgcagggct
     7981 tgattatttt aggattatag ctgcattact tataattgca attcatacat ctccattatt
     8041 atcatatagt aaaatggctg actttgtgtt aactagtata attgctcgta ttgctgtgcc
     8101 attctttttt atgctatcag gcttttttct aatttcaaca tataattata attgtaataa
     8161 actgaaatct tttctaaaaa atgtattatt tatttacggg atagctattg taatttatat
     8221 tcccttaaat atttacactg gatatttttc catgaataat ttagtgccca atattattaa
     8281 ggacattgta tttgatggga ctttatatca tttatggtat ctacctgcat caattattgg
     8341 tgcaagtatt gcatactttc ttgtaaaaaa actaggttta aagtactcat tagtaatcac
     8401 tattgttatt tatgtaattg gtatgtttgg tgatagttat tatggttttt tagaaaaaat
     8461 accactatta aagaatttat atgggtatat ttttgaagta tcagattata cacgaaatgg
     8521 tatatttttt gcacctgtat ttttcatact tggtggaata atatctaata aatctaatta
     8581 tatgtcaact aaaaatagct tgattggatt tcttatatca ttcttactta tgttatgtga
     8641 gggaatgttt ttacataaac taggggtaca gcgtcatgat agcatgtata ttatgttatt
     8701 gccatgtatg tatttcttat ttacagcctt aacattttta aaaggttctc gagctaggtt
     8761 attgcgaaca tcatcattaa ttatttatat tatacatcct atgatgattg ttgttattcg
     8821 tatgttttct aaaatattcg gaatacaaac tgtcttggtt gacaatagcc ttattcatta
     8881 tatagtggta agtatagcat cttttatagc ttctataatt attatattga ttcttaaacc
     8941 tctaaaaaaa gacttgaaag gagaacataa ggtaaatacc aatagagctt ggattgaaat
     9001 tgatttaaat aatttggaac ataatgtaaa gatgatacaa aaagctatgc cagaagattg
     9061 tgaattgatg gcagttgtaa aagctaatgc ctatggtcat agtgcttttg aagtagcgac
     9121 ttgtgcaaac caaataggtg taaaagcatt tgcagtagca acaatagatg aggggattga
     9181 tttacgtcga tatggaatac taggagaaat attgattctt ggatatacta acccaataag
     9241 ggcaaaggaa cttcataaat acaatcttac acagagtgtt attgacctta atcatgctat
     9301 ctctttaaac aaacagaaat acaacataaa atcacacatt aaaattgata caggtatgca
     9361 cagactgggt tttgatgtta atgatgtgag gtcaatttta aaggcattta aattaaaata
     9421 cttagatata tgtggcatat ttacacactt gtgtgtttca gatagtctga aagatgaaga
     9481 tgtagacttt acaaataaac aaattgaatg tttttataag ttaattgatt ttctgttaaa
     9541 aaaaggtata aaaattccta aagtacatat tcaaagtagt tatggttttt ttaattatcc
     9601 caatcttaag tgtaattatg taagaattgg aattgcatta tacgggatat taagttctcc
     9661 aaatgatacg actaaattgc aacttgattt acgacctgtt ttatccttaa aatcacaagt
     9721 aattcttatt agaaaaatac aaaaagatga tagttttgga tatggaagag tctttattgc
     9781 aagcagagat agcgtaattg ctatattatc tattggctat gccgatggta tacctagaaa
     9841 tttatcctgt ggaaaaagtt acgtaataat aaatggttgt agagcagcaa tagtgggtcg
     9901 aatttgcatg gaccaacttg ctgttgatat tacagatata cctaatgtag aagttggtaa
     9961 tacggcaata ataataggaa gagataattt atctgaatta tctgcttctg aagttgcaaa
    10021 taactcatgt agtatatcga atgaattatt gagcagagta ggaagaaggt taaatgttat
    10081 aaagaagtaa ctcaattaaa tagtaatatt tgttgtactg tgtaatttat tttactctga
    10141 ctagacattt ttagtaatat tatgtctaat atatattttt tataacttac atgacaattt
    10201 aagttataaa aaggtgatgt ttcagatttt tattttgaaa catcaccttt tttgttataa
    10261 tatataataa aataattata ccttaactgt aaacttatat agattattta ctttttaata
    10321 ttagattcat tttttgagat tggtatataa taaacatata gagtatataa taatagttaa
    10381 agttaaaaaa ggggaaaagc aatatgcagt atatacaaga attacttgat ttgactcaaa
    10441 attattgggt gttagccaca ataatcggct tattaagtgc atttatagaa agctttatac
    10501 cagccttacc acttgttgct atagttacag caaatgctgc aatacaagga ttatttattg
    10561 gatgtttgtt atcatggatt ggctcaggac ttgggacaac ttcattattc ttattaataa
    10621 gcagatttaa tgatagtaag ctttttaata agttgagaaa tagtaaaact gaaaaagcaa
    10681 taagttggat ggataaacag ggatttaagt tattatttat agcgtatgcc tgtccattta
    10741 tgcctggttg tttagttact atcgcatcag cttttggtaa aaaagattta aaagattttg
    10801 tgccagcaat gttggcagga aaatttgtaa tgtttatagt tataagttac gtggcaagtg
    10861 atatagaagg ttttataaca agtcctttaa agatagcatc atttatatta ttggtgtttt
    10921 tgtcatggaa gattggaaat agagtaaata aaaatcttga aaatcataat tatgatttcc
    10981 atcataaaaa acatcacaat gataaagatg ataaaatgat ttagcttgta cgaaataaaa
    11041 cgtatcttaa aatgatttag tactaaatta ttttaagata cgttttattt tttgtattaa
    11101 ggtacaaaat ttttagttct tttgtaaact aaaatatata aaacttattt atacttagtt
    11161 caaaat
//
LOCUS       DAEQJM010000191         8195 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.guided.112, whole genome shotgun sequence.
ACCESSION   DAEQJM010000191 DAEQJM010000000
VERSION     DAEQJM010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8195
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.guided.112"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            82..798
                     /locus_tag="KRQ43_003727"
     CDS             82..798
                     /locus_tag="KRQ43_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH2744053.1"
                     /translation="MILIVILSIFIIASINIIILGKENIRDIVIPLTLFIVSDFLFLC
                     GNIICRGGVMLLFIGLFAIPLMLIAFIWICVHMIKLYYKKDLNKRKMIGCIFSIFISI
                     GTIFIPSPSESFRFKLYEKDYSVVAKAILKVYDEKKLSSESVFYIQSDKNELEKIFSK
                     EVIKKMKKLNRNLDVVKISGNRNLVYFFFGAELQSIDGIVIFKDLKHVKPKLDFINRS
                     IQAPRLEYITNNVYYFKGEL"
     gene            826..1764
                     /gene="blaCDD"
                     /locus_tag="KRQ43_003728"
     CDS             826..1764
                     /gene="blaCDD"
                     /locus_tag="KRQ43_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH2744054.1"
                     /translation="MKRKNNFIWIVILLVVVAMGVYYVGRKHNNTKQKHDKNHINSEL
                     NKSKVENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETRRSPCS
                     TFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYYKKLID
                     KVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMAKI
                     FEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMLEREGD
                     TYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            2108..2791
                     /locus_tag="KRQ43_003729"
     CDS             2108..2791
                     /locus_tag="KRQ43_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH2744055.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2788..5448
                     /locus_tag="KRQ43_003730"
     CDS             2788..5448
                     /locus_tag="KRQ43_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH2744056.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAQKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDRTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKMS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKTVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNTRSRRQEFAMLRSVGLSPE
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5629..6810)
                     /locus_tag="KRQ43_003731"
     CDS             complement(5629..6810)
                     /locus_tag="KRQ43_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH2744057.1"
                     /translation="MKTPRNINSTVVFIIFCLIITFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6810..7472)
                     /locus_tag="KRQ43_003732"
     CDS             complement(6810..7472)
                     /locus_tag="KRQ43_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH2744058.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCGNISLNKVEVKAYLDNVEVLLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7617..8159)
                     /locus_tag="KRQ43_003733"
                     /pseudo
     CDS             complement(7617..8159)
                     /locus_tag="KRQ43_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
BASE COUNT         3044 a         1027 c         1298 g         2826 t
ORIGIN      
        1 ctattgtaat atttaaatat tacaatagta agttttaaat agagaataaa taattacctc
       61 acaaactgaa aggaggacat aatgatacta atagttatat tgagtatatt catcatagcc
      121 tcaatcaaca taattatatt aggtaaagaa aatataagag atatagttat ccctttaact
      181 ctatttattg taagtgattt tttatttttg tgtggaaata taatatgtag gggaggagta
      241 atgctactat ttataggttt atttgcaata ccattgatgc taattgcatt tatatggatt
      301 tgtgtacata tgattaagct ttactataaa aaagatttaa ataaaagaaa aatgattgga
      361 tgtatattta gtatctttat aagtataggt actatattta ttcctagtcc aagtgaaagt
      421 tttagattta aactttatga aaaagattat agtgtagtag ctaaagctat tttgaaagtt
      481 tatgatgaaa aaaagttaag ctctgaatct gtcttttata ttcaatctga taaaaatgaa
      541 ttggagaaga tattttctaa agaagtaata aaaaaaatga aaaaactaaa cagaaattta
      601 gatgtagtta aaatttctgg gaatagaaat ttagtctatt ttttctttgg agctgaatta
      661 caatctattg atggtattgt gatttttaaa gatttaaaac atgttaaacc aaagttagat
      721 tttataaata gaagtattca agctcctaga ttggagtata ttacaaataa tgtatattat
      781 tttaaaggtg aactataaac ttatgtagag gagatggtat aaagtatgaa aagaaaaaat
      841 aattttattt ggatagttat tcttctagtt gttgtagcta tgggagtata ttatgtagga
      901 agaaagcata acaacacaaa acaaaaacat gataagaatc atataaactc tgaattaaat
      961 aaatccaaag ttgaaaacaa tgataaaaac aaaaaagaaa aaattaatat ggttgactat
     1021 agtgactgtt ttgaaggtat tagtggagga gctatttttt ataatactaa aaataaagaa
     1081 tataatatat ataacaaaga attaattgaa acaagaaggt caccatgttc tacttttaaa
     1141 atagtttcaa ctttaattgg tttagaaaaa ggggtaataa actcaaaaga atcagttatg
     1201 ggatatgatg gtacagagta tccaaataaa aattggaata aaaatcttag tttagaagag
     1261 gcatttaagg agtcttgtgt ttggtactac aaaaaattga tagataaagt tgatgctaaa
     1321 tctgtccaaa acattttaga tgatttaaag tatgggaatt gcgatattag cgaatgggaa
     1381 ggagatttaa aaaatggaaa gggacattta aatggatttt ggttagaatc ttcattacaa
     1441 atatctccaa aagaacaagt gcaaacaatg gcaaaaatat ttgagggaga tacaaacttt
     1501 aaaaaagagc atattaatat tttaagagat attatgaaaa tagatgtaaa tgataaaaac
     1561 ataaatgtat atggaaaaac tggaacagga tttgatgaaa aaaataaacg tgtggatgca
     1621 tggtttgttg gtatgctaga gcgtgaaggt gacacctatt attttgctat taaatcagat
     1681 gattccaata aagaaattac agggccaaag gtaaaggaaa ttgcaattaa tataattaag
     1741 aaatattata gtgtaaggga ataaacttaa ttttatttgt aaatattatt tacctatagt
     1801 ctgtaatatt tattaaataa ttttactaaa ttgagtctat atagagcaaa actcctttag
     1861 tacataaaat acttgctatt gattattaaa ttgaatacct atagatttaa agttaatacc
     1921 ttttaaagac tatgtaatat attaaaagta taaataaaat atattgcata gtttttgttt
     1981 tatattataa ttttaaataa tgtgcaaaaa ctaaacaata tttttaatag taatttatat
     2041 ttgtattcat gtcactataa tgtcatttta ggttgctaaa atttaaccat aaaggagatg
     2101 attgtatatg gaaatattaa aatgtgaaaa tctcacaaaa atatatggtt caaatcaaac
     2161 cagagtgaca gcccttaata atgtaaattt atcagttcaa aaaggtgatt ttgtatccat
     2221 tgtaggagca tctggttctg gcaaatctac attgttacat ctgcttgggg gagtagatag
     2281 acctacatct ggaaagattt atgttgaaga tacagaaata tcaagtttaa aggaagaagc
     2341 tcttgcagtt tttagacgta gaaaagtagg tcttatttat caattttata atcttatacc
     2401 tacccttgat gttagaaaaa atatattatt acccatgtta cttgataaaa gaaaggtgga
     2461 tgaggataga ttctctgaga ttgtatctat attgggatta tctgatagat taaaccatct
     2521 tccaagtcaa ctttcaggtg gacaacaaca aagggtatct atagctagaa gtttaatcta
     2581 tagaccagct attttattag cagatgagcc aactggtaat cttgatagaa aaaattcaga
     2641 agaaattgta gacttgttaa acttatcaaa taaacgattt aatcagacaa tacttcttat
     2701 tactcatgat gagaaaatag cactagaggc aaatcgtatt gtaactatgg aagatggagt
     2761 gattgtctct gaaaaggtgg tgaagaaatg aatattcttc aagaatacac cttagacttt
     2821 gtacgacgca ataaacgtag tagtatagct ataatgttag ctatattact tactacaacc
     2881 atgatgtctt ctttgtgtgg actgttgtat accatgtgga cagattttat aagactttca
     2941 attgagaaag aaggtaactg gcatggtgaa ttgtttgact atacttatgg aagtgactta
     3001 ccattaattg aaaatttttc ttcagttgat gatgtaatgg taaaaggaca atggtatgta
     3061 ggcaaaatta atgatgagaa aagagattat ataatttata gaaatgctac atcagagtat
     3121 tggaattcta tgccagaaaa ggatactata atagagggtc gtcgaccaaa taatgctaat
     3181 gaaattgcat tatcaaaaca atattttgag aataatccaa gtgtaaaaat tggggataaa
     3241 attactcttc caataggaga tagaatccta aatggaaagc ctcttgaacc catagctcaa
     3301 aaatcgaaag gggaaagttt taaaaaaatt tcagagacta cattgacaat agtaggaaag
     3361 gtagatgttt ccacttcatc agtaatacct gcatatacag ctcttggata tcttgataga
     3421 acaagtataa aacctaatga tagtataact gtgtacttgc gatttaaaaa tataagagac
     3481 acatacaagg aacttccaaa acttgctaaa tcattggggt ggaagactaa tgaatatgga
     3541 aaatacaatc ttaaatataa tagtaattat cttttaaaaa tgttagtctt ttccccagaa
     3601 cagaaagcat ctatgagcag tatatcaaaa ttttcaactc ctattatgta tcttacaata
     3661 gcaattttta cagtagctgt gtttgtaatg gtgatttaca acgcgttttc actatctgca
     3721 aatgctagac ttactcaatt agggatatta tctagtgttg gtgcatcacc aaaacagatt
     3781 aaaatgtctg tagtgtttga aggttttttg cttacaatta taccattgcc aataggttta
     3841 tttttaggat ggttattgtg taataggctt atagtttata ttaattcagt taattatcat
     3901 actgatgttc cagaagtggt atttacttat ggtattcctg cttttctgcc agcagtttta
     3961 cttacaatag taacagtctg gatttctgca cttataccag cacgaaaagt atcaaagata
     4021 tctcctatag aagcaatacg acaaggagat agtgttaaaa tcaaaaagtc gcataaatat
     4081 tcattaggaa agatatttgg aatagaagga gaacttgcat caaacgcact acgtgctcgt
     4141 aaaaaatctt atcgtactgc aacaatatct ttaacattat cttttttatt acttacatgt
     4201 tttttgcata taattgcaaa tcaagaagga gcaaaagctg tttatggaag tgataattat
     4261 aaggaccaaa gagatatagc agtttatttg gaaaatagtg aacctgtaga gtctgctttc
     4321 attgaaaaat tagataatac agaaggtgta aaaagttcac tatattatca aaaaatgtct
     4381 gcttccactt ggctgactga aaaagatgca tcaaaagaac ttgcgaaaaa tggaggattt
     4441 aaaagtatag tttcatctaa aaaatactct cctatagaac gtgatggcaa gtttcgtata
     4501 atttcaaata taattgggct tgatgataag agttttacag aatattgtag gcaaatttct
     4561 gtagacccaa agttatttta tgatacaaaa aatccaacct caattgtata taataaggag
     4621 gaagatatta atcgtagtac acgtagaaat aaagtatata tagattattt aaatctttca
     4681 ataggagata acattaaatt aaatgaaaaa gtatatgacg aagataaagg ggattatact
     4741 tacaacatga aagtgggagc tattacaagc acacttccta aaacagtaga tactagttca
     4801 aaatatacat taatgcaaat agtgccaatg tctatggtgc aggaaatatc taaaaattat
     4861 gatgaagtaa gtaggttacg ttcaaatagg ctgataggag tatttaaagt aaataatcgt
     4921 gaggacattc ctagagtaag agaaaaatta gagtccattt ataataaaga ctatggttca
     4981 ggagattata gtattgagga tgttttagaa agtgaaaaac aaaaggctag tggaataaag
     5041 accatgaatt taatagtagg ctttattaca ggtttattgg ctatgattgg attatcaaat
     5101 gtacttgcta cagtgtcagg aaatactaga agtagacgac aagagtttgc tatgttgcgt
     5161 tctgttggat tatctccaga aggcataaaa aagatgcttg ttttggaagg tttgttctta
     5221 ggaattacac cattactact tagtattcct gtgcaaatag gaatagtgta tgcttttcta
     5281 cgtataaatg aaatatattt tatagagtat ttaccatttg cacctatatc tacaataata
     5341 ggttttacta tattgatact ttttattgta atagcatcat atatgacagg atacaagcag
     5401 ttgaagaatg aaaatatagt agaatctata aaaaatgaaa caatataaac aaaagctatt
     5461 tgaacttatt taaaggtttc gatttaagac tacttacaag tatagggata gttaatttgt
     5521 ttgtttaata aaaccttaaa tgtaaataga agtatattac taaaacaata gataacatag
     5581 aatatagata tagctggatt ataggtattt tacctataat ccagcatttt atgtgtaaaa
     5641 tttaattatg aatcttgcac caccattatg gcaattttct gcatgtagag taccattttg
     5701 acgttctata atagactttg atagagcaag ccctatacca atactgtcct tactagcatt
     5761 tttaccacga taaaatctat taaaaatata tggaagttct tcctgagcaa accctttacc
     5821 attatcttct atgataatct caacatatag aggattttga ctataataag caactatata
     5881 tccaccatct tctatatgct cactacaatt tttaagaata tttaaaagag cttctaaagt
     5941 ccaattaata tcgatttcaa attctaccga aggagaagcc tcgatagtaa atgtctgatg
     6001 tttttctctt aaagaacctt ctataggctc aattgcataa gtaagaagag aatgtacatc
     6061 tataagtttg ctttcaaata ttaaagtact tgcatccaat tttgataatg taagtaaaga
     6121 tgaaactagt ctctcaagtc ttgagatttg atttgtaagt ctgttaatat aatctatttc
     6181 ttcatctgga caattttctg aaagtaattg tgccataagt gacatagaag taattggagt
     6241 cttaagttga tgagcaatat ctgcaagatt atctgaaaga gtttgtcttt cttttaaagc
     6301 aaattctttt gaacaacgaa gttccccaac tgttttatat atctcatctt caaggtgaga
     6361 aaattcatct tcacatcgta aaagtacaga ctcttttcct aaattcactt cttctaagta
     6421 ttgagtaaga ttgtttattc tactcagttt ttgcttattt gttctatgtt tgattatata
     6481 tacaactgta gccattgttg aaattatacc aaacgatatc actagaaaat aaaaaaagtt
     6541 tttactccaa aatgtacttt tagaatatcc atgttttgat aaaatttcat ttcctgtttt
     6601 aaaatcctta tcactagaat ttttcagtga ttttagtata ctttctgtag acttaggatt
     6661 gtactcatat gatgcaccaa gagccttaga cagtacattg tattcattaa aagaagttat
     6721 agttgttaga attacactta ataaaaaagt tataattaag cagaatatta taaaaacaac
     6781 tgtactgttg atatttcttg gagttttcac tagctgtcct ccattctata tcctatgcct
     6841 cttaatgttt ttatacaagg tggatttttt aatttttctc taagacgctt tattgtaaca
     6901 gtaagagtgt tatcatttac gaaattacca tctacatccc agagcatttc tagtaacttt
     6961 gtacgggtca tagctctatt tttattttcc ataagactta gaagaagttt atattctcct
     7021 gctgtcaaaa gtacttcaac attatctaaa tatgctttga cttcaacttt attcaagctt
     7081 atatttccac atgtaatagt attgttagta tttgaatgag ttcttctaag aactgcatta
     7141 attctggatt gaagtactga gagcagaaat ggtttaacca catagtcatc tgcacccata
     7201 tctaatccac gtataatgtc tttttcatca tcacggactg tcaaaaatat cactggagta
     7261 tcttctatac ttttaacata ttggcaaaac tcgtatccaa taccatcagg tagatttaaa
     7321 tcaagcagaa ttaaatcaat agttttatca aaattttttt tagcttcagc aatcgtatta
     7381 taacaacata cagtgtgatt tttcttttca agggaagttt ttattccaaa tgtaattgta
     7441 tcatcatctt ctaaaagaag tattttagcc atttactttt agtcctttca gtaatttagt
     7501 tatttcatta actaagttat tagttttatg tttaatattt tttatgttag agatagaagt
     7561 tagagataga aaaaattatc atttaagtat ataaacttta atttataaac ttaggtttat
     7621 gctttaattg aatctattaa aagagcaaga gttgtttcaa taaatttttc ctcatctata
     7681 ttaaagttgt tcaggtatga ctttcctgtt acagatagta aattaaaaaa tcctgtaagt
     7741 gtaaatattg atgaatacat gagagtaggt atttcaatat catgcctaat acttctatca
     7801 ttttttccaa tttcaaacat tccttgtatt tcatcaaaca taaatttatt aaaagaaaaa
     7861 aacttttctt taaacagcat atcagtatcc gatttttcag agtttacaat accaatcatt
     7921 cccataaggc ataatagaga aggttctaca gagtaaaatt tatgaaaagc aaagtatgaa
     7981 agttttattt tttcaaaccc tgttttgcct tttgcacttt ctattttaac attatcccaa
     8041 agtcttttat atcctcttaa gacaacagca aagaataaat cttctttaca tgaaaagtac
     8101 ttgtatatgg tgcgtttagt atattcaact tcttttgcca actcattcat agttgtattc
     8161 tgaacctccc atgactaaag tcacagggtt cctgc
//
LOCUS       DAEQJM010000192         3624 bp    DNA     linear   BCT 18-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain MT5006
            SAMN12323918-rid12471853.guided.153, whole genome shotgun sequence.
ACCESSION   DAEQJM010000192 DAEQJM010000000
VERSION     DAEQJM010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN12323918
            Sequence Read Archive: SRR9719764
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068887.1
            Genome Coverage       :: 86x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/13/2021 20:19:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,736
            CDSs (total)                      :: 3,722
            Genes (coding)                    :: 3,679
            CDSs (with protein)               :: 3,679
            Genes (RNA)                       :: 14
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 6
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 43
            CDSs (without protein)            :: 43
            Pseudo Genes (ambiguous residues) :: 0 of 43
            Pseudo Genes (frameshifted)       :: 21 of 43
            Pseudo Genes (incomplete)         :: 22 of 43
            Pseudo Genes (internal stop)      :: 9 of 43
            Pseudo Genes (multiple problems)  :: 8 of 43
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3624
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN12323918-rid12471853.guided.153"
                     /strain="MT5006"
                     /isolation_source="Patients"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA"
                     /collected_by="Texas Medical Center, Houston, Texas- USA"
     gene            672..1304
                     /locus_tag="KRQ43_003734"
     CDS             672..1304
                     /locus_tag="KRQ43_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH2744059.1"
                     /translation="MTIPNSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVSPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(1675..2544)
                     /locus_tag="KRQ43_003735"
     CDS             complement(1675..2544)
                     /locus_tag="KRQ43_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH2744060.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(2641..3498)
                     /locus_tag="KRQ43_003736"
     CDS             complement(2641..3498)
                     /locus_tag="KRQ43_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH2744061.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
BASE COUNT         1267 a          542 c          394 g         1421 t
ORIGIN      
        1 cccacatatt ttagaaaagg tactctataa tatacaaaca cttctttttt acctaaattt
       61 attttaacat tctataattt tcacaatatt ctttaaattt tactcatata aacaatatta
      121 ttctggatgc taatagaatt aatctataaa tcatagtata attatgcaga aataactcga
      181 atttcactac ttataaagag attgaatatt aatgaatcta aatcatttgc attacttcag
      241 agttttgact aaagttgaac accatacaaa agtagctact caattgttta taccccaacc
      301 aagcttaagt aatgttatat agattcttga aaaagaattt ggtatctttt tatttgaaaa
      361 acaaggtaga aatgtttccc tcactaaata cggaagtttt tttctaacct atgttgataa
      421 agcattaggt taattagaaa aagtttacat ataaaatata ttaaattgtt gcaagtttta
      481 ttgttttgat atacaatcaa ctaaacatat aatctttata aaatactata cagttaaaag
      541 tctgttttaa aaaaaaatgt ataaattata aatcaaaata tagatactat caaggagtga
      601 ttctgtgaag agatgtattg tagtagtgga atagtcaaaa acataatata tattaaagga
      661 gagatttaaa tatgactatt ccaaattcaa ataaggtata tccaagaagt aatgattatc
      721 aaactgtata tcttaaaaat gtaataacaa gggaaaatat agaagttgga gattacacaa
      781 tatataatga cttttataat gacccaagag attttgagaa aaacaatgta ttatatcatt
      841 accctataaa caatgataaa ttaataattg gtaagttttg ctcaatagca tgtaatgcaa
      901 aatttctaat gactagtgga aatcactcaa tgaaatcaaa atccacatat acttttccca
      961 tcttttatga agaatggaaa ctcgatatca accatataac ggacgcttgg gacaataagg
     1021 gtaacattat aattggaaat gatgtgtgga taggttatga ttctataatt atgtcaggtg
     1081 taaatattgg tgatggtgca attattggaa caagagcagt agttactaat gacgtctcac
     1141 cgtattctat tgttggagga gtacctgcaa aaattataaa aaagagattt aataatgata
     1201 caatttcaaa attattagaa attaaatggt gggattggcc atataaaaaa attcaatcaa
     1261 acattaagca tattcaatca ggaaatattg ataaattagt ttaatatttt ataatttatt
     1321 tatattaaac tttactttaa taatcctttt ataagagctt tttcaaaatt tgtatattat
     1381 tttaatatat ataaatttaa tacaacatta aataaaataa aaagtaaagt tacttaataa
     1441 aaagttactt tactttttat tatttaaatt cctgttttta ttataatagg taaaattcta
     1501 ttaaactagt tcacattttc attattattg atatattata tatgaatata ccattttgtt
     1561 ttttaataaa aaaatcatgc tacatcagta gtaagcaact attaatgtag catgattttt
     1621 tgtatctaaa taatcttagt atttacctat caatatagat tgatatatca aaaactatag
     1681 tcttctatat tcttctcttt ttagcttttg gttacttaga tagtaatcaa tttcatcaat
     1741 tagacgttgt ttatcatcag gtaatacacc ttttaaatta gcataatttg atgcatgatt
     1801 acttctaaat acaatttttt cattagcatc tatattcttt atcatctctt taatttcttg
     1861 taacacagcc ttatcctcta gtattgtaaa ctctcctgcc ttaagtaaat cgtaaagttc
     1921 agtattaggt tctaccatta aactaagtac acccacataa tctggtgaaa ttgctcctaa
     1981 catttttcct gtatcaactg catgctgatg tgttttttta gttcctccaa gacctgctat
     2041 tacagtggct gataatttaa tcccactttt tttaactttt ctaccaactt ttattaattg
     2101 ttcactacta aaacctttct taatatcttc taatacttca ttgcttccac tttcaagccc
     2161 tagataaatc attttaacac caagttttct taattcttta agttcatcat cagatttttt
     2221 ctctatagat ttaggagagc cgtacatagt aattctttca cactctggaa aaacttcttt
     2281 tatatataaa ataatatctc ttaatttctc cattggtatt atcaatgcat ctccatctgc
     2341 taagaatatt ctttctacat gcttataata tcttctaaat atatcaattt cattttttat
     2401 tacttctagt ggctttattt taaatttttt agatttgtac atactacaaa acgtacattt
     2461 gttatgagaa catcctagtg tgacttgtat tataagacta taagcctcac ttggtggtct
     2521 gtaaagtggc atatcgtatt ccatattaaa atcccccttg taataaaata ttcattctat
     2581 tatattatta atatttactt taaataataa cttataaaat tatatttttt aaattttagt
     2641 ttaagatata ttctttaaaa atttaatgat actattggca gtaatattaa gttgtttttc
     2701 ttgacttata atagcatcat tatctccctt ttgttttcca tagtctccaa attgtgcatg
     2761 atttcctcct tcaatctcaa cataagttgt atcatcagga agtttttgtt ttgattctac
     2821 aagactttta aaattgacta ctccatcttt gctcccccat atagatataa ctttttttcc
     2881 taattctttc aactcatcac ccattggata agaagctaaa aatacaacgc cttcaattaa
     2941 tttattatca cgtgcaaaat ttgatgctgc aactcctcct aatgaatgac ctcctattac
     3001 ccaatgttct atgttgttgt aagaatccat aactttctgt gccttattag ttccaagtat
     3061 agctagatta agtggcatct ttacgattac aacctcatat ccactttctg ctatttttct
     3121 tgcaagtgga gcataagatt ctatttctac tttagctcct ggatacaaaa ttaaaccttt
     3181 agaaactttt cttccttttg gtgtaaatga aatgttttca tttacagtta cttcaacttt
     3241 actattgctg actagagctt cttttgccag cttttgaggt tcatatgttt tatttatcca
     3301 tatgaaaaag ccaagcaaaa tcaatacaaa tagtatacct attcccttaa atatcttatt
     3361 ctttatgtta aattttctat tattattttt atcatctttg ttctcaacct catcataaag
     3421 taaaggtctc tcaagttcca tagttatact aaatgtatca tatttcttat tacgctttac
     3481 ctttacatct ttactcataa atctaacccc cataatattt gaatactatt atagtttatc
     3541 ctaagtaaat tgttttttca accaatgaaa aaaatcaata ttttaactat tttcatataa
     3601 aattcataaa tatatgtttt ttgt
//
